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Sample records for reported concentration type

  1. High surface hole concentration p-type GaN using Mg implantation

    International Nuclear Information System (INIS)

    Long Tao; Yang Zhijian; Zhang Guoyi

    2001-01-01

    Mg ions were implanted on Mg-doped GaN grown by metalorganic chemical vapor deposition (MOCVD). The p-type GaN was achieved with high hole concentration (8.28 x 10 17 cm -3 ) conformed by Van derpauw Hall measurement after annealing at 800 degree C for 1 h. this is the first experimental report of Mg implantation on Mg-doped GaN and achieving p-type GaN with high surface hole concentration

  2. High surface hole concentration p-type GaN using Mg implantation

    CERN Document Server

    Long Tao; Zhang Guo Yi

    2001-01-01

    Mg ions were implanted on Mg-doped GaN grown by metalorganic chemical vapor deposition (MOCVD). The p-type GaN was achieved with high hole concentration (8.28 x 10 sup 1 sup 7 cm sup - sup 3) conformed by Van derpauw Hall measurement after annealing at 800 degree C for 1 h. this is the first experimental report of Mg implantation on Mg-doped GaN and achieving p-type GaN with high surface hole concentration

  3. Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Daniel Espes

    2014-01-01

    Full Text Available Betatrophin has recently been described as a key hormone to stimulate beta-cell mass expansion in response to insulin resistance and obesity in mice. The finding has generated an interest in the development of antidiabetic drugs with betatrophin as the active component. However, the circulating levels of betatrophin in patients with type 2 diabetes are not well known. Betatrophin concentrations in plasma of 27 type 2 diabetes patients and 18 gender-, age-, and BMI-matched controls were measured. Study participants were characterized with regard to BMI, waist and hip circumference, blood pressure, and fasting plasma blood lipids, creatinine, glucose, HbA1c, and C-peptide. HOMA2 indices were calculated. Betatrophin was 40% higher in patients with type 2 diabetes (893±80 versus 639±66 pg/mL. Betatrophin positively correlated with age in the controls and with HbA1c in the type 2 diabetes patients. All study participants were insulin resistant with mean HOMA2B IR in both groups exceeding 2 and HOMA2%S<50%. Control individuals had impaired fasting glucose concentrations. In this report on betatrophin concentrations in type 2 diabetes and insulin resistance, elevated betatrophin levels were measured in the patients with type 2 diabetes. Future studies are clearly needed to delineate the exact role, if any, of betatrophin in regulating human beta-cell mass.

  4. Type II GaSb quantum ring solar cells under concentrated sunlight.

    Science.gov (United States)

    Tsai, Che-Pin; Hsu, Shun-Chieh; Lin, Shih-Yen; Chang, Ching-Wen; Tu, Li-Wei; Chen, Kun-Cheng; Lay, Tsong-Sheng; Lin, Chien-Chung

    2014-03-10

    A type II GaSb quantum ring solar cell is fabricated and measured under the concentrated sunlight. The external quantum efficiency confirms the extended absorption from the quantum rings at long wavelength coinciding with the photoluminescence results. The short-circuit current of the quantum ring devices is 5.1% to 9.9% more than the GaAs reference's under various concentrations. While the quantum ring solar cell does not exceed its GaAs counterpart in efficiency under one-sun, the recovery of the open-circuit voltages at higher concentration helps to reverse the situation. A slightly higher efficiency (10.31% vs. 10.29%) is reported for the quantum ring device against the GaAs one.

  5. Segregation of chlorine in n-type tin monosulfide ceramics: Actual chlorine concentration for carrier-type conversion

    Science.gov (United States)

    Iguchi, Yuki; Sugiyama, Taiki; Inoue, Kazutoshi; Yanagi, Hiroshi

    2018-05-01

    Tin monosulfide (SnS) is an attractive material for photovoltaic cells because of its suitable band-gap energy, high absorption coefficient, and non-toxic and abundant constituent elements. The primary drawback of this material is the lack of n-type SnS. We recently demonstrated n-type SnS by doping with Cl. However, the Cl-doped n-type SnS bulk ceramics exhibited an odd behavior in which carrier-type conversion but not electron carrier concentration depended on the Cl concentration. In this study, the electron probe microanalysis (EPMA) elemental mapping of Cl-doped SnS revealed continuous homogeneous regions with a relatively low Cl concentration along with the islands of high Cl concentration in which Sn/S is far from unity. The difference between the Cl concentration in the homogeneous region (determined by EPMA) and the bulk Cl concentration (determined by wavelength-dispersive X-ray fluorescence spectroscopy) increased with the increasing Cl doping amount. The carrier concentration and the Hall coefficient clearly depended on the Cl concentration in the homogeneous region. Carrier-type conversion was observed at the Cl concentration of 0.26 at. % (in the homogeneous region).

  6. Technical Performance and Clinical Effectiveness of Drop Type With Adjustable Concentrator-Cell Free and Concentrated Ascites Reinfusion Therapy.

    Science.gov (United States)

    Yamada, Yosuke; Harada, Makoto; Yamaguchi, Akinori; Kobayashi, Yasuko; Chino, Takashi; Minowa, Takashi; Kosuge, Takashi; Tsukada, Wataru; Hashimoto, Koji; Kamijo, Yuji

    2017-12-01

    Cell-free and concentrated ascites reinfusion therapy (CART) is a very useful treatment method for refractory ascites but is difficult for many hospitals to employ due to its need for specialized equipment. We have therefore developed drop-type with adjustable concentrator CART (DC-CART) that uses a drop-type filtration mechanism and requires only a simple pump and pressure monitor for its concentration process. Easy adjustment of ascites concentration is possible through a recirculation loop, and filter membrane washing is aided by DC-CART's external pressure-type filtration to enable the processing of any quality or quantity of ascites. Moreover, the absence of a roller pump before filtration avoids inflammatory substance release from compressed cells. A total of 268 sessions of DC-CART using ascites from 98 patients were performed with good clinical results at our hospitals between January 2012 and June 2016. This report presents the detailed methods of DC-CART and summarizes its clinical effectiveness using patient ascites and blood data obtained from 59 sessions between March 2015 and February 2016. This novel technique successfully processed refractory ascites in numerous diseases with no serious adverse events. DC-CART could concentrate large amounts of ascites (from median weight: 4900 g [max: 20 200 g] to median weight: 695 g; median concentration ratio: 7.4), and a high amount of protein (median weight: 73 g [max: 294 g]) could be reinfused. Serum albumin levels were significantly increased (P = 0.010) and kidney function and systemic hemodynamics were well maintained in treated subjects. Additional concentration of ascites and adjustment of ascites volume were easily performed by recirculation (from median weight: 615 g to median weight: 360 g; median concentration ratio: 1.5). Time was needed during DC-CART for filter membrane cleaning, especially for viscous ascites. Overall, DC-CART represents a safe and useful treatment method for various forms

  7. Blood metals concentration in type 1 and type 2 diabetics.

    Science.gov (United States)

    Forte, Giovanni; Bocca, Beatrice; Peruzzu, Angela; Tolu, Francesco; Asara, Yolande; Farace, Cristiano; Oggiano, Riccardo; Madeddu, Roberto

    2013-12-01

    Mechanisms for the onset of diabetes and the development of diabetic complications remain under extensive investigations. One of these mechanisms is abnormal homeostasis of metals, as either deficiency or excess of metals, can contribute to certain diabetic outcomes. Therefore, this paper will report the blood levels of chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), mercury (Hg), nickel (Ni), lead (Pb), selenium (Se), and zinc (Zn) in subjects with type 1 diabetes (n = 192, mean age 48.8 years, mean disease duration 20.6 years), type 2 diabetes (n = 68, mean age 68.4 years, mean disease duration 10.2 years), and in control subjects (n = 59, mean age 57.2 years), and discuss the results indicating their possible role in diabetes. The metal concentrations were measured by sector field inductively coupled plasma mass spectrometry after microwave-induced acid digestion of blood samples. The accuracy was checked using a blood-based certified reference material, and recoveries of all elements were in the range of 92-101 % of certified values. Type 1 diabetes was found to be associated with Cr (p = 0.02), Mn (p < 0.001), Ni (p < 0.001), Pb (p = 0.02), and Zn (p < 0.001) deficiency, and type 2 diabetes with Cr (p = 0.014), Mn (p < 0.001), and Ni (p < 0.001) deficiency. These deficiencies were appreciated also subdividing the understudied patients for gender and age groups. Furthermore, in type 1 diabetes, there was a positive correlation between Pb and age (p < 0.001, ρ = 0.400) and Pb and BMI (p < 0.001, ρ = 0.309), while a negative correlation between Fe and age (p = 0.002, ρ = -0.218). In type 2 diabetes, there was a negative correlation between Fe and age (p = 0.017, ρ = -0.294) and Fe and BMI (p = 0.026, ρ = -0.301). Thus, these elements may play a role in both forms of diabetes and combined mineral supplementations could have beneficial effects.

  8. Serum uric acid concentration in patients with type-2 diabetes mellitus during diet or glibenclamide therapy

    International Nuclear Information System (INIS)

    Mahmood, I.H.

    2007-01-01

    To investigate serum uric acid concentration in patients with type 2 diabetes mellitus. This is a case control study conducted in Al-Wafa Diabetic Center in Mosul over a period of one year starting from January 1, 2005 to January 1, 2006. Serum glucose concentration and uric acid concentration were measured in both control and patient's groups (group 1 patients on diet therapy, group 2 patients on glibenclamide therapy and group 3 involve naturopathic patients). Serum glucose concentration was high in the diabetic groups as compared with the control group (P 0.2) except in group-3 (P<0.05). A negative correlation was reported between hyperglycemia and uric acid concentration of the different groups. Serum uric acid concentration is slightly reduced in type 2 diabetic patients particularly in the complicated patients with peripheral neuropathy and this may be due to the oxidative stress that decreases the antioxidant capacity of the body involving uric acid. (author)

  9. Effect of ventilation type on radon concentration at places of work

    International Nuclear Information System (INIS)

    Oksanen, E.

    1994-01-01

    Indoor radon ( 222 Rn) concentrations were measured at 76 child care facilities and 36 schools in southern Finland. The buildings had three different types of ventilation systems: mechanical air supply and exhaust, mechanical exhaust, and natural ventilation, the first being most common. The effect of the ventilation type on the long-term radon concentration was studied in child care facilities. The radon concentrations were highest in the naturally ventilated buildings. The mechanical air supply and exhaust system maintained the lowest values in cold wintertime. In school buildings both the long-term radon concentration and short-term radon and daughter concentrations were measured. The correlation of the ventilation type and the radon concentration was not obvious in this group of measurements, but the radon concentrations and the equilibrium factors were highest in buildings with natural ventilation. Radon concentrations were generally lower during the working hours than during the one-month period, as expected. (author)

  10. Dissolved organic carbon (DOC) concentrations in UK soils and the influence of soil, vegetation type and seasonality.

    Science.gov (United States)

    van den Berg, Leon J L; Shotbolt, Laura; Ashmore, Mike R

    2012-06-15

    Given the lack of studies which measured dissolved organic carbon (DOC) over long periods, especially in non-forest habitat, the aim of this study was to expand the existing datasets with data of mainly non-forest sites that were representative of the major soil and habitat types in the UK. A further aim was to predict DOC concentrations from a number of biotic and abiotic explanatory variables such as rainfall, temperature, vegetation type and soil type in a multivariate way. Pore water was sampled using Rhizon or Prenart samplers at two to three week intervals for 1 year. DOC, pH, organic carbon, carbon/nitrogen (C:N) ratios of soils and slope were measured and data on vegetation, soil type, temperature and precipitation were obtained. The majority of the variation in DOC concentrations between the UK sites could be explained by simple empirical models that included annual precipitation, and soil C:N ratio with precipitation being negatively related to DOC concentrations and C:N ratio being positively related to DOC concentrations. Our study adds significantly to the data reporting DOC concentrations in soils, especially in grasslands, heathlands and moorlands. Broad climatic and site factors have been identified as key factors influencing DOC concentrations. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Sugar type and concentration preference of the Cape white-eye ...

    African Journals Online (AJOL)

    . ... Minke Witteveen, Mark Brown ... sugar type preference at any sugar concentration, but showed a preference for the lowest concentration (10%) of both hexose and sucrose solutions when presented with a range of sugar concentrations.

  12. Liver/kidney microsomal antibody type 1 and liver cytosol antibody type 1 concentrations in type 2 autoimmune hepatitis.

    Science.gov (United States)

    Muratori, L; Cataleta, M; Muratori, P; Lenzi, M; Bianchi, F B

    1998-05-01

    Liver/kidney microsomal antibody type 1 (LKM1) and liver cytosol antibody type 1 (LC1) are the serological markers of type 2 autoimmune hepatitis (AIH). Since LKM1 and LC1 react against two distinct liver specific autoantigens (cytochrome P450IID6 (CYP2D6) and a 58 kDa cytosolic polypeptide respectively), the aim was to see whether LKM1 and LC1 concentrations correlate with liver disease activity. Twenty one patients with type 2 AIH were studied. All sera were tested by indirect immunofluorescence, counterimmunoelectrophoresis, and immunoblotting visualised by enhanced chemiluminescence. To evaluate LKM1 and LC1 levels, the 50 kDa microsomal reactivity (corresponding to CYP2D6) and the 58 kDa cytosolic reactivity were quantified by densitometric analysis. Seven patients were positive for LKM1, nine for LC1, and five for both. Serial serum samples at onset and during immunosuppressive treatment were analysed in 13 patients (four positive for LKM1, six positive for LC1 and three positive for both). During remission, LKM1 concentration remained essentially unchanged in six of seven patients, and decreased in only one. Conversely, in two of nine patients, LC1 was completely lost, and, in the remaining seven, LC1 concentration was reduced by more than 50%. After immunosuppression tapering or withdrawal, flare ups of liver necrosis ensued with increasing LC1 concentration, but not LKM1. LC1 concentration, at variance with that of LKM1, parallels liver disease activity, and its participation in the pathogenic mechanisms of liver injury can be hypothesised.

  13. Development and fabrication of a concentrating solar collector subsystem (quarterly reports)

    Energy Technology Data Exchange (ETDEWEB)

    1978-07-01

    Work done from January 1, 1978 through June 30, 1978, including several types of testing and results and evaluation of the structural design of the Northrup ''ML Series'' Concentrating Solar Collector, Model NSC-01-0732 and the Attitude Control System is reported. Efficiency tests, stagnation--defocusing tests, internal vacuum tests, pressure tests, tracking tests, fluttering tests, accelerated swivel and flexible joint life tests, and certification are described.

  14. Determination of atmospheric concentrations of xenon radioisotopes. Progress report

    International Nuclear Information System (INIS)

    Abel, K.H.; Panisko, M.E.; Hensley, W.K.; Bowyer, T.W.; Perkins, R.W.

    1995-07-01

    Determination of radioactive xenon concentrations in the atmosphere over a two year period has been performed as part of a research program to develop real-time measurement capabilities. The initial measurements were made to develop, prove, and validate the authors technical approach, while the longer-term measurements are being undertaken to establish natural background concentrations and variability with time. The results reported were made using noble gas fraction (typically 90% Kr and 10% Xe by weight) gas samples obtained from a commercial air-reduction plant in the northeastern US over a two-year interval beginning in the fall of 1993. The concentrated gas samples were typically obtained during a 6--8 hour interval at the commercial reduction plant and were shipped overnight to their laboratory. Analysis was typically completed approximately 24 hours after sampling. The analytical separation process typically took approximately 6 hours and gamma-ray spectrometric measurements were conducted for intervals ranging from 3 to 16 hours. The technical approach involved removal of potentially interfering radon daughter radionuclides using a molecular sieve at room temperature, followed by cryogenic concentration of noble gases using a chilled (-76 C) activated carbon molecular sieve. During initial measurements both molecular sieve materials were contained in 30 foot x 1/4 inch gas chromatography columns for analytical separations. Krypton was separated from Xenon during the analytical procedure by warming the activated carbon molecular sieve to room temperature after initial noble gas concentration and actively pumping it away. Xenon-133 adsorbed to the activated charcoal molecular sieve was then quantified via its 81 keV gamma-ray using initially a p-type intrinsic germanium detector and later a higher efficiency (64% relative to a 3 inch x 3 inch sodium iodide) n-type intrinsic germanium detector

  15. Serum bilirubin concentration is associated with eGFR and urinary albumin excretion in patients with type 1 diabetes mellitus.

    Science.gov (United States)

    Nishimura, Takeshi; Tanaka, Masami; Sekioka, Risa; Itoh, Hiroshi

    2015-01-01

    Although relationships of serum bilirubin concentration with estimated glomerular filtration rate (eGFR) and urinary albumin excretion (UAE) in patients with type 2 diabetes have been reported, whether such relationships exist in patients with type 1 diabetes is unknown. A total of 123 patients with type 1 diabetes were investigated in this cross-sectional study. The relationship between bilirubin (total and indirect) concentrations and log(UAE) as well as eGFR was examined by Pearson's correlation analyses. Multivariate regression analyses were used to assess the association of bilirubin (total and indirect) with eGFR as well as log(UAE). A positive correlation was found between serum bilirubin concentration and eGFR; total bilirubin (r=0.223, p=0.013), indirect bilirubin (r=0.244, p=0.007). A negative correlation was found between serum bilirubin concentration and log(UAE); total bilirubin (r=-0.258, p=0.005), indirect bilirubin (r=-0.271, p=0.003). Multivariate regression analyses showed that indirect bilirubin concentration was an independent determinant of eGFR and log(UAE). Bilirubin concentration is associated with both eGFR and log(UAE) in patients with type 1 diabetes. Bilirubin might have a protective role in the progression of type 1 diabetic nephropathy. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Serum alpha-tocopherol and ascorbic acid concentrations in Type 1 and Type 2 diabetic patients with and without angiopathy.

    Science.gov (United States)

    Skrha, Jan; Prázný, Martin; Hilgertová, Jirina; Weiserová, Hana

    2003-03-01

    Alpha-tocopherol and ascorbic acid form a part of scavenger system influencing the level of oxidative stress in diabetes mellitus. The aim of this study was to evaluate serum concentrations of alpha-tocopherol and ascorbic acid in Type 1 and Type 2 diabetes mellitus and to compare them with the presence of vascular complications as well as with oxidative stress and endothelial dysfunction. A total of 38 Type 1 and 62 Type 2 diabetic patients were subdivided into those with and without angiopathy. Serum alpha-tocopherol and ascorbic acid concentrations were estimated in all patients and in 38 healthy persons. Their results were compared with diabetes control, with oxidative stress measured by plasma malondialdehyde and with endothelial dysfunction estimated by serum N-acetyl-beta-glucosaminidase activity. In addition, the differences in biochemical variables were compared between patients with and without angiopathy. Serum alpha-tocopherol related to the sum of cholesterol and triglyceride concentrations (AT/CHT ratio) was significantly lower in diabetic patients with macroangiopathy than in those without vascular changes (pascorbic acid levels were significantly lower only in Type 2 diabetic patients with macroangiopathy as compared with healthy controls as well as with patients without vascular disease (pcholesterol or triglyceride concentrations in both Type 1 and Type 2 diabetic patients. The presence of oxidative stress together with endothelial dysfunction measured by N-acetyl-beta-glucosaminidase activity was accompanied by lower AT/CHT ratio (pascorbic acid concentration in serum. Their low concentrations may participate at the increased level of oxidative stress in these individuals.

  17. Development of mediator-type biosensor to wirelessly monitor whole cholesterol concentration in fish.

    Science.gov (United States)

    Takase, Mai; Murata, Masataka; Hibi, Kyoko; Huifeng, Ren; Endo, Hideaki

    2014-04-01

    We developed a wireless monitoring system to monitor fish condition by tracking the change in whole cholesterol concentration. The whole cholesterol concentration of fish is a source of steroid hormones or indicator of immunity level, which makes its detection important for tracking physiological condition of fish. Wireless monitoring system comprises of mediator-type biosensor and wireless transmission device. Biosensor is implantable to fish body, and transmission device is so light, in that fish is allowed to swim freely during monitoring. Cholesterol esterase and oxidase were fixated on to the detection site of biosensor and used to detect the whole cholesterol concentration. However, cholesterol oxidase incorporates oxidation-reduction reaction of oxygen for detection, which concentration fluctuates easily due to change in environmental condition. Meanwhile, mediator-type biosensor enables monitoring of whole cholesterol concentration by using mediator to substitute that oxidation-reduction reaction of oxygen. Characteristic of fabricated mediator-type biosensor was tested. The sensor output current of mediator-type biosensor remained stable compared to output current of non-mediator-type biosensor under fluctuating oxygen concentration of 0-8 ppm, which implied that this sensor is less affected by change in dissolved oxygen concentration. That biosensor was then implanted into fish for wireless monitoring. As a result, approximately 48 h of real-time monitoring was successful.

  18. Liver/kidney microsomal antibody type 1 and liver cytosol antibody type 1 concentrations in type 2 autoimmune hepatitis

    OpenAIRE

    Muratori, L; Cataleta, M; Muratori, P; Lenzi, M; Bianchi, F

    1998-01-01

    Background—Liver/kidney microsomal antibody type 1 (LKM1) and liver cytosol antibody type 1 (LC1) are the serological markers of type 2 autoimmune hepatitis (AIH). 
Aims—Since LKM1 and LC1 react against two distinct liver specific autoantigens (cytochrome P450IID6 (CYP2D6) and a 58 kDa cytosolic polypeptide respectively), the aim was to see whether LKM1 and LC1 concentrations correlate with liver disease activity. 
Patients—Twenty one patients with type 2 AIH were studied. 
Methods—A...

  19. Performance comparisons of dish type solar concentrator with mirror arrangements and receiver shapes

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Joo Hyun; Kim, Yong; Ma, Dae Sung; Seo, Tae Beom [Graduate School, Dept. of Mechanical Engineering, Inha Univ., Inchon (Korea, Republic of); Kang, Yong Heack [Korea Inst. of Energy Research, Daejeon (Korea, Republic of)

    2008-07-01

    The performance comparisons of dish type solar concentrators are numerically investigated. The dish type solar concentrator considered in this paper consists of a receiver and multi-faceted mirrors. In order to investigate the performance comparisons of dish type solar concentrators, six different mirror arrangements and four different receivers are considered. A parabolic-shaped perfect mirror of which diameter is 1.40 m is considered as the reference for the mirror arrangements. The other mirror arrangements consist of twelve identical parabolic-shaped mirror facets of which diameter are 0.405 m. Their total collecting areas, which are 1.545 m{sup 2}, are the same. Four different solar receiver shapes are a conical, a dome, a cylindrical, and a unicorn type. In order to investigate the thermal performance of the dish type solar concentrator, the radiative heat loss in the receiver should be calculated. For calculation, the net radiation method and the Monte-Carlo method are used. Also, because the thermal performance of the dish type solar concentrator can vary as the receiver surface temperature, the various surface temperatures are considered. Based on the calculation, the unicorn type has the best performance in receiver shapes and the STAR has the best performance in mirror arrangements except the perfect mirror. (orig.)

  20. Nutrient Infiltrate Concentrations from Three Permeable Pavement Types

    Science.gov (United States)

    While permeable pavement is increasingly being used to control stormwater runoff, field-based, side-by-side investigations on the effects different pavement types have on nutrient concentrations present in stormwater runoff are limited. In 2009, the U.S. EPA constructed a 0.4-ha...

  1. Compensation of native donor doping in ScN: Carrier concentration control and p-type ScN

    Science.gov (United States)

    Saha, Bivas; Garbrecht, Magnus; Perez-Taborda, Jaime A.; Fawey, Mohammed H.; Koh, Yee Rui; Shakouri, Ali; Martin-Gonzalez, Marisol; Hultman, Lars; Sands, Timothy D.

    2017-06-01

    Scandium nitride (ScN) is an emerging indirect bandgap rocksalt semiconductor that has attracted significant attention in recent years for its potential applications in thermoelectric energy conversion devices, as a semiconducting component in epitaxial metal/semiconductor superlattices and as a substrate material for high quality GaN growth. Due to the presence of oxygen impurities and native defects such as nitrogen vacancies, sputter-deposited ScN thin-films are highly degenerate n-type semiconductors with carrier concentrations in the (1-6) × 1020 cm-3 range. In this letter, we show that magnesium nitride (MgxNy) acts as an efficient hole dopant in ScN and reduces the n-type carrier concentration, turning ScN into a p-type semiconductor at high doping levels. Employing a combination of high-resolution X-ray diffraction, transmission electron microscopy, and room temperature optical and temperature dependent electrical measurements, we demonstrate that p-type Sc1-xMgxN thin-film alloys (a) are substitutional solid solutions without MgxNy precipitation, phase segregation, or secondary phase formation within the studied compositional region, (b) exhibit a maximum hole-concentration of 2.2 × 1020 cm-3 and a hole mobility of 21 cm2/Vs, (c) do not show any defect states inside the direct gap of ScN, thus retaining their basic electronic structure, and (d) exhibit alloy scattering dominating hole conduction at high temperatures. These results demonstrate MgxNy doped p-type ScN and compare well with our previous reports on p-type ScN with manganese nitride (MnxNy) doping.

  2. Model for calculating the boron concentration in PWR type reactors

    International Nuclear Information System (INIS)

    Reis Martins Junior, L.L. dos; Vanni, E.A.

    1986-01-01

    A PWR boron concentration model has been developed for use with RETRAN code. The concentration model calculates the boron mass balance in the primary circuit as the injected boron mixes and is transported through the same circuit. RETRAN control blocks are used to calculate the boron concentration in fluid volumes during steady-state and transient conditions. The boron reactivity worth is obtained from the core concentration and used in RETRAN point kinetics model. A FSAR type analysis of a Steam Line Break Accident in Angra I plant was selected to test the model and the results obtained indicate a sucessfull performance. (Author) [pt

  3. Wild-type minimal inhibitory concentration distributions in bacteria of animal origin in Argentina

    Directory of Open Access Journals (Sweden)

    Florencia L Pantozzi

    Full Text Available The aim of this study was to determine the antimicrobial resistance profiles of indicator bacteria isolated from domestic animal feces. Minimal inhibitory concentration (MIC was determined by agar dilution. Interpretative criteria on the basis of wild-type MIC distributions and epidemiological cutoff values (ECOFF or ECV were used according to the 'European Committee on Antimicrobial Susceptibility Testing' (EUCAST data. Results from 237 isolates of Escherichia coli showed reduced susceptibility for ampicillin, streptomycin and tetracycline, the antimicrobials commonly used in intensive breeding of pigs and hens. Regarding all the species of the genus Enterococcus spp., there are only ECOFF or ECV for vancomycin. Of the 173 Enterococcus spp. isolated, only one showed reduced susceptibility to vancomycin and was classified as 'non-wild-type' (NWT population. This is the first report in Argentina showing data of epidemiological cutoff values in animal bacteria.

  4. Explant age, auxin concentrations and media type affect callus ...

    African Journals Online (AJOL)

    The effects of explant age of oil palm (Elaeis huineensis) embryo axes, 15 and 18 weeks after anthesis (WAA), media type (Eeuwens and Murashige and Skoog) supplemented with various concentrations of 2,4-D on callus production employing standard in vitro techniques were investigated. The results of the study showed ...

  5. Nonimaging compound parabolic concentrator-type reflectors with variable extreme direction.

    Science.gov (United States)

    Gordon, J M; Rabl, A

    1992-12-01

    The properties of nonimaging compound parabolic concentrator (CPC)-type devices are examined in which the extreme direction is not constant but rather is a variable that can change along the reflector. One can then retain the maximal concentration or radiative efficiency of the CPC while the flux map on the absorber or target is modified, depending on whether the device is used for optical concentration or for lighting. Two general classes of reflector are derived, and all the nonimaging devices developed to date are shown to be special cases of the general solution. These two classes are the nonimaging analog of converging and diverging devices of imaging optics.

  6. Relationship between serum adiponectin concentration and diabetic nephropathy in patients with type 2 diabetes mellitus

    International Nuclear Information System (INIS)

    Zhu Wei; Yang Yuzhi; Li Xianhou; Feng Kun; Wang Dan

    2007-01-01

    Objective: To investigate the relationship between serum adiponectin concentration and diabetic nephropathy in patients with type 2 diabetes mellitus. Methods: The serum adiponectin concentrations were measured with RIA in 163 patients with type 2 diabetes mellitus and 50 controls. Results: In the diabetic patients, serum adiponectin concentrations were significantly higher in patients with macro albuminuria (n = 54) than those inpatients with microalbuminuria (n = 57) (P 0.05). Adiponectin concentrations were higher in women than in men, but there was no significant difference (P > 0.05). Conclusion: Serum adiponectin concentrations are increased in type 2 diabetic patients with advanced nephropathy. The kidney seems to be involved in the metabolism and excretion of adiponectin. Adiponectin may play important roles in the onset and development of diabetic nephropathy. (authors)

  7. Effects of bedrock type on the indoor radon concentrations at the office buildings in Gyeongju, Korea

    Directory of Open Access Journals (Sweden)

    Park Hee Chan

    2011-01-01

    Full Text Available This study measured the indoor radon concentrations at 23 administrative office buildings in Gyeongju, Korea, which consists of 23 administrative districts. Using the Korean geological information system, the type of bedrock under the administrative office buildings was identified and classified in 3 major types: granite, sedimentary rock, and sedimentary rock-based fault. The changes in the indoor concentrations at the 23 administrative office buildings were analyzed according to the type of bedrock. As a result, the radon concentration in the areas with the granite bedrock was generally higher than that in the region of two other types of bedrock. In addition, the radon concentration was evaluated according to surface area and construction timing of the building. The indoor radon concentration generally increased with decreasing surface area of the building, particularly in granite distributed areas. For a building aged more than 15 years, the radon concentration in the building in the granite area was much higher. For the building aged 1 or 2 years, the radon concentration was high regardless of the type of the bedrock due to radon emanation from the building material, such as concrete.

  8. Pregnancy-induced rise in serum C-peptide concentrations in women with type 1 diabetes

    DEFF Research Database (Denmark)

    Nielsen, Lene Ringholm; Rehfeld, Jens F; Pedersen-Bjergaard, Ulrik

    2009-01-01

    OBJECTIVE: The purpose of this study was to investigate whether pregnancy induces increased insulin production as a marker of improved beta-cell function in women with long-term type 1 diabetes. RESEARCH DESIGN AND METHODS: This was a prospective study of 90 consecutive pregnant women with type 1.......85). Multivariate regression analysis revealed a positive association between the absolute increase in C-peptide concentrations during pregnancy and decreased A1C from 8 to 33 weeks (P = 0.003). CONCLUSIONS: A pregnancy-induced increase in C-peptide concentrations in women with long-term type 1 diabetes...... in 35 women. RESULTS: C-peptide concentrations gradually increased throughout pregnancy regardless of serum glucose concentrations in the 90 women with a median duration of diabetes of 17 years (range 1-36 years). Among 35 women with paired recordings of stimulated C-peptide, C-peptide production...

  9. Indoor radon concentration and its possible dependence on ventilation rate and flooring type

    International Nuclear Information System (INIS)

    Ashok, G. V.; Nagaiah, N.; Shiva Prasad, N. G.

    2012-01-01

    The results of radon concentration measurements carried out in dwellings with natural ventilation for 1 y in Bangalore are reported. Measurements, covering three sessions of the day (morning, afternoon, night) were performed two times in a month for 1 y at a fixed place of each dwelling at a height of 1 m above the ground surface in selected dwellings. The low-level radon detection system (LLRDS), an active method, was used for the estimation of radon concentration. The measurements were aimed to understand the diurnal variation and the effect of ventilation rate and flooring type on indoor radon concentration. The geometric mean (±geometric standard deviation) of indoor radon concentration from about 500 measurements carried out in 20 dwellings is found to be 25.4 ±1.54 Bq m -3 . The morning, afternoon and night averages were found to be 42.6 ±2.05, 15.3 ±2.18 and 28.5 ±2.2 Bq m -3 , respectively. The approximate natural ventilation rates of the dwellings were calculated using the PHPAIDA-the on-line natural ventilation, mixed mode and air infiltration rate calculation algorithm and their effects on indoor radon concentrations were studied. The inhalation dose and the lung cancer risk due to indoor radon exposure were found to be 0.66 mSv y -1 and 11.9 per 10 6 persons, respectively. The gamma exposure rate was also measured in all the dwellings and its correlation with the inhalation dose rate was studied. (authors)

  10. Exercise timing and blood lactate concentrations in individuals with type 2 diabetes.

    Science.gov (United States)

    Heden, Timothy D; Liu, Ying; Kanaley, Jill A

    2017-07-01

    The purpose of this study was to characterize how resistance exercise prior to or after a meal alters fasting and postprandial blood lactate concentrations in individuals with type 2 diabetes. Obese individuals with type 2 diabetes (N = 12) completed three 2-day trials, including (i) no exercise (NoEx), (ii) resistance exercise prior to dinner (Ex-M), and (iii) resistance exercise beginning at 45 min postdinner (M-Ex). During day 1 of each trial, fasting and postprandial blood lactate concentrations, perceived exertion, and substrate oxidation were measured, and subsequently on day 2 the following morning fasting blood lactate was measured. The premeal lactate incremental area under the curve (iAUC) during Ex-M (109 ± 66 mmol·L -1 ·1.6 h -1 ) was over 100-fold greater (P 0.05). Perceived exertion, substrate oxidation, or fasting blood lactate concentrations the day after testing were not different between trials. Blood lactate concentrations during acute resistance exercise are greater when exercise is performed in the postprandial period. Acute resistance exercise performed the night prior does not alter fasting blood lactate concentrations the following morning.

  11. Solar concentrators. Concentradores solares

    Energy Technology Data Exchange (ETDEWEB)

    Almanza, R.; Valdes, A.; Lopez, S.

    1981-06-01

    This paper presents different types of geometries used in concentrators. Some comments are made on the theoretical and experimental analysis necessary to evaluate the geometries and on the type of laboratory equipment needed to obtain experimental data. At the end of the report a description of how to build parabolic trough mirrors is made. The experience gained by the authors, who have been working in this subject for the past five years, is summarized, showing some of the problems related with such concentrators.

  12. Sensitive Capacitive-type Hydrogen Sensor Based on Ni Thin Film in Different Hydrogen Concentrations.

    Science.gov (United States)

    Pour, Ghobad Behzadi; Aval, Leila Fekri; Eslami, Shahnaz

    2018-04-01

    Hydrogen sensors are micro/nano-structure that are used to locate hydrogen leaks. They are considered to have fast response/recovery time and long lifetime as compared to conventional gas sensors. In this paper, fabrication of sensitive capacitive-type hydrogen gas sensor based on Ni thin film has been investigated. The C-V curves of the sensor in different hydrogen concentrations have been reported. Dry oxidation was done in thermal chemical vapor deposition furnace (TCVD). For oxidation time of 5 min, the oxide thickness was 15 nm and for oxidation time 10 min, it was 20 nm. The Ni thin film as a catalytic metal was deposited on the oxide film using electron gun deposition. Two MOS sensors were compared with different oxide film thickness and different hydrogen concentrations. The highest response of the two MOS sensors with 15 nm and 20 nm oxide film thickness in 4% hydrogen concentration was 87.5% and 65.4% respectively. The fast response times for MOS sensors with 15 nm and 20 nm oxide film thickness in 4% hydrogen concentration was 8 s and 21 s, respectively. By increasing the hydrogen concentration from 1% to 4%, the response time for MOS sensor (20nm oxide thickness), was decreased from 28s to 21s. The recovery time was inversely increased from 237s to 360s. The experimental results showed that the MOS sensor based on Ni thin film had a quick response and a high sensitivity.

  13. Effect of sample type, centrifugation and storage conditions on vitamin D concentration.

    Science.gov (United States)

    Colak, Ayfer; Toprak, Burak; Dogan, Nese; Ustuner, Fusun

    2013-01-01

    Studies about vitamin D [25(OH)D] stability in plasma are limited and preanalytical variables such as tube type may affect results. We aimed to evaluate effect of storage conditions, sample type and some preanalytical variables on vitamin D concentration. Blood samples from 15 healthy subjects were centrifuged at different temperatures and stored under different conditions. Serum and plasma 25(OH)D difference, effect of centrifugation temperature and common storage conditions were investigated. There was no difference between serum and plasma vitamin D concentration. Centrifugation temperature had no impact on vitamin D concentration. 25(OH)D is stable under common storage conditions: 4 hours at room temperature, 24 hours at 2-8 degrees C, 7 days at -20 degrees C, 3 months at -80 degrees C. Vitamin D does not require any special storage conditions and refrigeration. Both serum and plasma can be used for measurement.

  14. Serum leptin concentration in patients with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Malecha-Jedraszek Arleta

    2015-12-01

    Full Text Available With the increasing importance of early type 2 diabetes (DM2 and obesity detection, it is useful to reevaluate leptin role in these conditions. Our study aimed at investigating circulating leptin concentrations in a group of patients with DM2, and at assessing in detail whether leptin concentrations correlate with selected biochemical, clinical parameters and markers of systemic inflammation in patients with DM2 and in healthy volunteers. In our work, we analysed samples and data drawn from 71 patients aged 61.4 ± 11.7 years, who have been diagnosed with type 2 diabetes, as well as from a healthy control group (HC consisting of 51 healthy subjects with a mean age of 57.8 ± 13.7 years. Therein, the concentration of leptin in the DM2 patients was significantly higher than in the HC (p < 0.01, with median value of 16.59 (IQR 8.58-33.39 ng/ml in the DM2, vs median value of 6.66 (IQR 4.52-21.40 ng/ml in the HC. In the analysis of variance, higher leptin concentrations were revealed in the DM2 group as compared to the HC, and this figure remained significant after adjusting for gender and age (p < 0.001. Moreover, it was independent of HOMA-IR (p = 0.003. However, the differences in leptin levels between the groups disappeared when additional adjustments for anthropometric parameters (BMI, waist circumference were applied (p = 0.088. Beyond the aforementioned, significant positive correlations were found in the DM 2 group between leptin level and CRP (r=0.256; p < 0.05 and IL-6 (r = 0.345; p < 0.01. Among the selected variables, only gender and BMI were included in the predictive model explaining the variability of leptin, and, in total, were responsible for 72.6% of the original variation of the studied adipocytokine. The results of this study have led to conclusion that leptin may participate in the complex pathogenesis of DM2 and be a predictor of the development of this disease. As higher concentrations of leptin coexist with obesity, and this

  15. Salivary flow rate, buffer capacity, and urea concentration in adolescents with type 1 diabetes mellitus.

    Science.gov (United States)

    Saes Busato, Ivana Maria; Antoni, Carlos Cesar De; Calcagnotto, Thiago; Ignácio, Sérgio Aparecido; Azevedo-Alanis, Luciana Reis

    2016-12-01

    The objective of the study was to analyze salivary flow rate, urea concentration, and buffer capacity in adolescents with type 1 diabetes mellitus (type 1 DM) in two different stages. This study was performed on adolescents (14-19 years), allocated between two groups: type 1 DM group comprised 32 adolescents with type 1 DM, and non-type 1 DM group comprised 32 nondiabetics. The adolescents in type 1 DM group were evaluated at a baseline (T0) and after 15 months (T1), and those in non-type 1 DM group were only evaluated at T0. Diabetic status was determined by glycosylated hemoglobin (GHb) and capillary glucose tests. Measurement of salivary flow was performed by means of stimulated saliva (SSFR) collection. The buffer capacity (BC) was determined, and analysis of urea salivary concentration was performed using the colorimetric method. At T0, there were significant differences between diabetics and nondiabetics for SSFR and BC (pdiabetics, SSFR was 0.790 mL/min in T0 and 0.881 mL/min in T1 (p>0.05). BC at T0 was 4.8, and at T1, it was 3.9 (p=0.000). Urea concentration mean value had a significant decrease at T1 (28.13) compared with T0 (34.88) (p=0.013). There was a negative correlation between SSFR and urea salivary concentration at both T0 (r=-0.426, p≤0.05) and T1 (r=-0.601, p≤0.01). In adolescents with type 1 DM, hyposalivation at T0 was associated with an increase in urea salivary concentration. At T1, hyposalivation was associated with a reduction in BC, and an increase in salivary urea.

  16. Effect of dissolved hydrogen concentration on IASCC initiation susceptibility of type 316 stainless steels

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Min-Jae; Kim, Sung Woo; Hwang, Seong Sik [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    The effect of DH concentration on PWSCC of nickel based alloys has been studied, higher dissolved hydrogen strategy is being considered to obtain partial mitigation of PWSCC. In the case of stainless steels, it is necessary to research the effect of DH concentration on irradiation assisted stress corrosion cracking(IASCC). In this research, we tried to evaluate the effect of DH concentration on IASCC initiation susceptibility using the proton irradiated type 316 stainless steels under the condition of simulated primary water. The slow strain rate tests were performed using the proton irradiated type 316 stainless steels at the simulated primary water conditions, crack length per unit area for all tested specimens were calculated. IASCC initiation susceptibility was increased by increasing irradiation doses and by increasing DH concentration.

  17. Plasma heme oxygenase-1 concentration is elevated in individuals with type 2 diabetes mellitus.

    Directory of Open Access Journals (Sweden)

    Wei Bao

    Full Text Available BACKGROUND: Circulating concentrations of heme oxygenase-1 (HO-1 have been recently reported to be elevated in several chronic disorders. However, no study has ever examined the association between circulating HO-1 concentrations and type 2 diabetes mellitus (T2DM. METHODS AND FINDINGS: 581 cases with newly-diagnosed T2DM (New-T2DM and 611 comparison controls were recruited in this two-phase case-control study, comprising 420 cases and 429 controls collected in the first phase study and 161 cases and 182 controls in the second phase replication study. Analyses, using both separated data and combined data from the two-phase studies, show that plasma HO-1 concentrations were significantly increased in New-T2DM cases compared to controls (P<0.001. Plasma HO-1 concentrations were significantly correlated with plasma glucose concentrations, HOMA-beta and HOMA-IR (P<0.001. After adjustment for age, sex, BMI and family history of diabetes, the ORs for New-T2DM in the highest quartile of plasma HO-1 concentrations, compared with the lowest, was 8.23 (95% CI 5.55-12.21; P for trend <0.001. The trend remained significant after additional adjustment for fasting plasma glucose/insulin, HOMA-beta/HOMA-IR, TC/TG, smoking, drinking and history of hypertension, and even in further stratification analysis by age, sex, BMI, smoking, drinking and history of hypertension. CONCLUSIONS: Elevated plasma HO-1 concentrations are associated with higher ORs for New-T2DM, which add more knowledge regarding the important role of oxidative stress in T2DM. More consequent studies were warranted to confirm the clinical utility of plasma HO-1, especially in diagnosis and prognosis of T2DM and its complications.

  18. Pfeiffer syndrome type 2: case report

    Directory of Open Access Journals (Sweden)

    Maria Kiyoko Oyamada

    Full Text Available OBJECTIVE: To report on a case of Pfeiffer Syndrome, with a discussion of the diagnostic characteristics and features of disease types and the differential diagnosis. DESCRIPTION: The authors describe a newborn with cloverleaf skull, extreme bilateral exorbitism and choanal atresia, partial syndactyly of the second and third toes and broad medially-deviated big toes. The case reported was Pfeiffer Syndrome type 2, which usually has a poor prognosis. COMMENTS: Pfeiffer Syndrome is a clinically variable disorder and consists of an autosomal dominantly-inherited osteochondrodysplasia with craniosynostosis. It has been divided into three types. Type 1 is commonly associated with normal intelligence and generally good outcome. Types 2 and 3 generally have severe neurological compromise, poor prognosis, early death and sporadic occurrence. Potential for prolonged useful survival outcome can be achieved in some cases with early aggressive medical and surgical management according to recent literature.

  19. Effect of fertilizer type on cadmium and fluorine concentrations in clover herbage

    International Nuclear Information System (INIS)

    McLaughlin, M.J.

    2002-01-01

    This study investigated whether changing phosphatic fertilizer type affects the accumulation of cadmium (Cd) and fluorine (F) in pasture herbage. North Carolina phosphate rock and partially acidulated fertilizers derived from this rock generally have higher Cd and F concentrations compared to single superphosphate currently manufactured in Australia. Clover herbage from sites of the National Reactive Phosphate Rock (RPR) trial was collected and analysed for concentrations of Cd (11 sites) and F (4 sites). A comparison was made between pastures fertilized with 4 rates of single superphosphate, North Carolina phosphate rock, and partially acidulated phosphate rock having Cd concentrations of 283, 481, and 420 mg Cd/kg P respectively, and 170, 271, and 274 g F/kg P respectively. One site used Hemrawein (Egypt) phosphate rock (HRP) having a Cd and F concentration of 78 mg Cd/kg P and 256 g F/kg P respectively. To help identify differences in herbage Cd concentrations between sites, unfertilised soils from each site were analyzed for total and extractable Cd contents. At one site Cd concentrations in bulk herbage (clover, grasses and weeds) were related to infestation of the pasture by capeweed (Arctotheca calendula L. Levyns). There were no significant differences between F in herbage from plots fertilized with single superphosphate, partially acidulated phosphate rock or North Carolina phosphate rock, or between sites. Concentrations of F in herbage were low, generally less than 10 mg F /kg. However, there were large differences in Cd concentrations in herbage between sites, while differences between fertilizer treatments were small in comparison. The site differences were only weakly related to total or extractable (0.01 mol/L CaCl 2 ) Cd concentrations in soil. Significant differences in Cd concentrations in clover due to fertilizer type were found at 5 sites. North Carolina phosphate rock treatments had significantly higher Cd concentrations in clover compared to

  20. Reporting Severe Hypoglycemia in Type 1 Diabetes

    DEFF Research Database (Denmark)

    Pedersen-Bjergaard, Ulrik; Thorsteinsson, Birger

    2017-01-01

    PURPOSE OF REVIEW: To describe potential factors influencing reporting of severe hypoglycemia in adult patients with type 1 diabetes and to analyze their effect on reported rates of severe hypoglycemia. RECENT FINDINGS: Reported rates of severe hypoglycemia defined as need for third party...... by partners report higher rates of severe hypoglycemia. There is a large variation between studies reporting incidence and prevalence of severe hypoglycemia in patients with type 1 diabetes, mainly explained by definition of severity, methods of reporting, and patient selection. These findings call...... hypoglycemia are 0.02-0.5 events per patient-year and 1-29%, respectively. When subjects with recurrent severe hypoglycemia in the past or suffering from impaired hypoglycemia awareness are excluded from participation in studies, lower rates are reported. Studies applying anonymous reporting or reporting...

  1. A discussion about maximum uranium concentration in digestion solution of U3O8 type uranium ore concentrate

    International Nuclear Information System (INIS)

    Xia Dechang; Liu Chao

    2012-01-01

    On the basis of discussing the influence of single factor on maximum uranium concentration in digestion solution,the influence degree of some factors such as U content, H 2 O content, mass ratio of P and U was compared and analyzed. The results indicate that the relationship between U content and maximum uranium concentration in digestion solution was direct ratio, while the U content increases by 1%, the maximum uranium concentration in digestion solution increases by 4.8%-5.7%. The relationship between H 2 O content and maximum uranium concentration in digestion solution was inverse ratio, the maximum uranium concentration in digestion solution decreases by 46.1-55.2 g/L while H 2 O content increases by 1%. The relationship between mass ratio of P and U and maximum uranium concentration in digestion solution was inverse ratio, the maximum uranium concentration in digestion solution decreases by 116.0-181.0 g/L while the mass ratio of P and U increase 0.1%. When U content equals 62.5% and the influence of mass ratio of P and U is no considered, the maximum uranium concentration in digestion solution equals 1 578 g/L; while mass ratio of P and U equals 0.35%, the maximum uranium concentration decreases to 716 g/L, the decreased rate is 54.6%, so the mass ratio of P and U in U 3 O 8 type uranium ore concentrate is the main controlling factor. (authors)

  2. Influence of source type and air exchange on variations of indoor radon concentration

    International Nuclear Information System (INIS)

    Arvela, H.; Winqvist, K.

    1986-04-01

    The model relates radon concentration to source strength and its variations, air exchange rate and meteorological factors. Two types of sources have been studied. The pressure difference dependent source is made up of radon transported with soil pore air and driven by pressure difference due to the stack effect. The constant source is made up of radon transported by diffusion from building materials or from soil. The air exchange rate depends exponentially on indoor-outdoor temperature difference and linearly on wind speed. These two inputs have been summed in quadrature. In a house with a constant source radon concentration decreases when the air exchange rate increases due to the increasing temperature difference, whereas the pressure difference dependent source causes an increasing concentration. This is due to the fact that the effect of the source strength increase is stronger than the decreasing effect of air exchange on concentration. The winter-summer concentration ratio depends on the combination of the two types of source. A pure pressure dependent source leads to the winter-summer ratio of 2-3.5 (winter -5 deg C, summer +15 deg C, wind speed 3 m/s). A strong contribution of a constant source is needed to cause a summer concentration higher than the winter concentration. The model is in agreement with the winter-summer concentration ratios measured. This ratio increases with the increasing winter concentration. The measured ratio was near 1.0 for houses with winter concentration of 200 Bq m''3 or less and near 2.0 with concentration of 1000 Bq m''3. In a house with a constant source, the diurnal maximum occurs in the afternoon, while in houses with a pressure difference dependent source the time of maximum is early in the morning

  3. Coating of evaporation concentrates with bitumen. Progress Report No. 1

    International Nuclear Information System (INIS)

    Rodier, J.; Lefillatre, G.; Rodi, L.; Cudel, Y.

    1968-01-01

    Laboratory tests have been carried out on the coating by bitumen of evaporation concentrates having a free nitric acidity of 1 N or 2.5 N, and a high mineralization (400 gm/litre). In order to neutralize the free acidity and to trap the radio-elements, these concentrates have been subjected before coating to various treatments designed to decrease the solubility. As a result of these treatments, sludges were obtained which could be coated directly with the bitumen. By measuring the radioactive diffusion factors of the bitumen coated products immersed both in ordinary and sea water, it was possible to compare the efficiency of the processes developed and of the various types of bitumen used. On the whole the radioactive diffusion tests were satisfactory and the process using successive co-precipitations (hydroxides, nickel ferrocyanide, barium sulphate) was chosen. From the bitumens tried out, a straight - asphalt, Mexphalt 40/50 was selected for low and medium activity concentrates as it ensures good isolation of the radio-elements; an air-blowing asphalt, Mexphalte R 90/40, was chosen for concentrates of high activity because of its higher resistance to irradiation. As a result of this work, a simple coating technology was evolved and pilot experiments will soon begin. Briefly, it appears that although a method for coating evaporation concentrates with bitumen has been defined, it will inevitably be necessary to devise a specific decontamination process each time that a new type of concentrate is encountered (composition, nature of the salts, radio-element distribution). (author) [fr

  4. An analysis of factors affecting the high radon concentration in different types of houses

    Directory of Open Access Journals (Sweden)

    Gulan Ljiljana

    2017-01-01

    Full Text Available This paper presents an analysis of indoor radon measurements carried out in municipality of Zubin Potok, northwestern part of Kosovo and Metohija. Annual measurements in two rooms of each house were performed by solid state nuclear track detectors commercially known as Gammadata. Average indoor radon concentration in different type of houses varied from 29-326 Bq/m3. A different year of house's construction including various types of building materials were selected for survey. A detail analysis showed that the differences in radon concentration occur between various building materials used for construction, flooring level, type of room and behavior of inhabitants. It was found that building materials in some houses contribute additionally to indoor radon.

  5. Effects of forage:concentrate ratio and forage type on apparent digestibility, ruminal fermentation, and microbial growth in goats.

    Science.gov (United States)

    Cantalapiedra-Hijar, G; Yáñez-Ruiz, D R; Martín-García, A I; Molina-Alcaide, E

    2009-02-01

    The effects of forage type and forage:concentrate ratio (F:C) on apparent nutrient digestibility, ruminal fermentation, and microbial growth were investigated in goats. A comparison between liquid (LAB) and solid (SAB)-associated bacteria to estimate microbial N flow (MNF) from urinary purine derivative excretion was also examined. Treatments were a 2 x 2 factorial arrangement of forage type (grass hay vs. alfalfa hay) and high vs. low F:C (70:30 and 30:70, respectively). Four ruminally cannulated goats were fed, at maintenance intake, 4 experimental diets according to a 4 x 4 Latin square design. High-concentrate diets resulted in greater (P 0.05) when diets included alfalfa hay. Total protozoa numbers and holotricha proportion were greater and less (P forage used. The MNF measured in goats fed different diets was influenced by the bacterial pellet (LAB or SAB). In addition, the purine bases:N ratio values found were different from those reported in the literature, which underlines the need for these variables to be analyzed directly in pellets isolated from specific animals and experimental conditions.

  6. The hydrogen and deuterium concentrations in chondrites

    International Nuclear Information System (INIS)

    Robert, F.; Merlivat, L.

    1978-01-01

    Water and isotopic concentration of H 2 O + are reported. It shows a correlation between the water, the deuterium concentrations and the petrologic types of chondrites. The Chainpur meteorite has been divided into several mineralogical fractions and the results are reported. The results of Orgueil are also reported. The correlation shows that as the sulfate content increases, the water and deuterium contents decrease. The terrestrial contamination is discussed and possible deuterium variation models are presented

  7. Determination of breath isoprene and acetone concentration with a needle-type extraction device in gas chromatography-mass spectrometry.

    Science.gov (United States)

    Ueta, Ikuo; Mizuguchi, Ayako; Okamoto, Mitsuyoshi; Sakamaki, Hiroyuki; Hosoe, Masahiko; Ishiguro, Motoyuki; Saito, Yoshihiro

    2014-03-20

    Isoprene in human breath is said to be related to cholesterol metabolism, and the possibility of the correlations with some clinical parameters has been studied. However, at this stage, no clear benefit of breath isoprene has been reported for clinical diagnosis. In this work, isoprene and acetone concentrations were measured in the breath of healthy and obese subjects using a needle-type extraction device for subsequent analysis in gas chromatography-mass spectrometry (GC-MS) to investigate the possibility of these compounds as an indicator of possible diseases. After measuring intraday and interday variations of isoprene and acetone concentrations in breath samples of healthy subjects, their concentrations were also determined in 80 healthy and 17 obese subjects. In addition, correlation between these breath concentrations and the blood tests result was studied for these healthy and obese subjects. The results indicated successful determination of breath isoprene and acetone in this work, however, no clear correlation was observed between these measured values and the blood test results. Breath isoprene concentration may not be a useful indicator for obesity or hypercholesterolemia. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Salt type and concentration affect the viscoelasticity of polyelectrolyte solutions

    Science.gov (United States)

    Turkoz, Emre; Perazzo, Antonio; Arnold, Craig B.; Stone, Howard A.

    2018-05-01

    The addition of small amounts of xanthan gum to water yields viscoelastic solutions. In this letter, we show that the viscoelasticity of aqueous xanthan gum solutions can be tuned by different types of salts. In particular, we find that the decrease in viscoelasticity not only depends, as is known, on the salt concentration, but also is affected by the counterion ionic radius and the valence of the salt.

  9. Adipocytokine concentrations in children with different types of beta-thalassemia.

    Science.gov (United States)

    Enli, Yaşar; Balci, Yasemin I; Gönen, Cafer; Uzun, Ebru; Polat, Aziz

    2014-06-01

    Beta-thalassemia is an inherited blood disorder. It results from the impaired production of β-globin chains, leading to a relative excess of alpha-globin chains. Clinical severity separates this disease into three main subtypes: β- thalassemia major, β-thalassemia intermedia and β-thalassemia minor, the former two being clinically more significant. Inflammatory processes may play an important role in some of the complications of thalassemia. Adipose tissue is one of the most important endocrine and secretory organs that release adipocytokines like adiponectin, resistin and visfatin. The aim of our study was to analyze adipocytokine concentrations (adiponectin, resistin and visfatin) in different types of β-thalassemia patients and determine any possible correlations with disease severity. We recruited 29 patients who were transfusion-dependent β-thalassemia-major patients, 17 patients with β-thalassemia intermedia, 30 β-thalassemia minor patients. The control group consisted of 30 healthy children. Anthropometric measurements, complete blood count, biochemical parameters, serum concentrations of adiponectin, resistin, visfatin were performed for all subjects. Resistin and visfatin concentrations were significantly higher in β-thalassemia minor patients than in controls. Adiponetin, resistin and visfatin concentrations were significantly higher in both β-thalassemia intermedia and major patients than in controls. The concentrations of adiponectin, resistin and visfatin were significantly higher in both β-thalassemia intermedia and major patients than in β-thalassemia minor patients. There was no significant difference between β-thalassemia intermedia and β-thalassemia major patients for adipocytokines concentrations. We speculate that these adipocytokines may play a role in the development of complications in β-thalassaemia.

  10. Plasma adiponectin concentrations are associated with dietary glycemic index in Malaysian patients with type 2 diabetes.

    Science.gov (United States)

    Loh, Beng-In; Sathyasuryan, Daniel Robert; Mohamed, Hamid Jan Jan

    2013-01-01

    Adiponectin, an adipocyte-derived hormone has been implicated in the control of blood glucose and chronic inflammation in type 2 diabetes. However, limited studies have evaluated dietary factors on plasma adiponectin levels, especially among type 2 diabetic patients in Malaysia. The aim of this study was to investigate the influence of dietary glycemic index on plasma adiponectin concentrations in patients with type 2 diabetes. A cross-sectional study was conducted in 305 type 2 diabetic patients aged 19-75 years from the Penang General Hospital, Malaysia. Socio-demographic information was collected using a standard questionnaire while dietary details were determined by using a pre-validated semi-quantitative food frequency questionnaire. Anthropometry measurement included weight, height, BMI and waist circumference. Plasma adiponectin concentrations were measured using a commercial ELISA kit. Data were analyzed using multiple linear regression. After multivariate adjustment, dietary glycemic index was inversely associated with plasma adiponectin concentrations (β =-0.272, 95% CI -0.262, - 0.094; pfoods containing high dietary glycemic index that plasma adiponectin level reduced by 0.3 μg/mL. Thirty two percent (31.9%) of the variation in adiponectin concentrations was explained by age, sex, race, smoking status, BMI, waist circumference, HDL-C, triglycerides, magnesium, fiber and dietary glycemic index according to the multiple linear regression model (R2=0.319). These results support the hypothesis that dietary glycemic index influences plasma adiponectin concentrations in patients with type 2 diabetes. Controlled clinical trials are required to confirm our findings and to elucidate the underlying mechanism.

  11. Concentration Levels of Imidacloprid and Dinotefuran in Five Tissue Types of Black Walnut, Juglans nigra

    Directory of Open Access Journals (Sweden)

    Paul Merten

    2013-11-01

    Full Text Available Black walnut, a valuable economic and environmentally important species, is threatened by thousand cankers disease. Systemic imidacloprid and dinotefuran applications were made to mature black walnut trees to evaluate their translocation and concentration levels in various tissue types including leaf, twig, trunk core, nutmeat, and walnut husk. The metabolism of imidacloprid in plants produces a metabolite, olefin-imidacloprid, which has been documented to have insecticidal properties in other systems. Trunk CoreTect (imidacloprid soil pellets and a trunk spray of dinotefuran were applied to mature black walnuts in spring 2011. Imidacloprid concentrations were detected in both the lower and upper strata in all tissue types tested and progressively increased through month 12 post-treatment in twig and leaf tissue. Olefin-imidacloprid was detected in the nutmeat and walnut husk. Dinotefuran was only detected in the first sampling period and was found in low concentration levels in leaf and twig tissue types, and was not detected in the trunk, nutmeat or the walnut husk.

  12. Typing Style and the Use of Different Sources of Information during Typing: An Investigation Using Self-Reports.

    Science.gov (United States)

    Rieger, Martina; Bart, Victoria K E

    2016-01-01

    We investigated to what extent different sources of information are used in typing on a computer keyboard. Using self-reports 10 finger typists and idiosyncratic typists estimated how much attention they pay to different sources of information during copy typing and free typing and how much they use them for error detection. 10 finger typists reported less attention to the keyboard and the fingers and more attention to the template and the screen than idiosyncratic typists. The groups did not differ in attention to touch/kinaesthesis in copy typing and free typing, but 10 finger typists reported more use of touch/kinaesthesis in error detection. This indicates that processing of tactile/kinaesthetic information may occur largely outside conscious control, as long as no errors occur. 10 finger typists reported more use of internal prediction of movement consequences for error detection than idiosyncratic typists, reflecting more precise internal models. Further in copy typing compared to free typing attention to the template is required, thus leaving less attentional capacity for other sources of information. Correlations showed that higher skilled typists, regardless of typing style, rely more on sources of information which are usually associated with 10 finger typing. One limitation of the study is that only self-reports were used. We conclude that typing task, typing proficiency, and typing style influence how attention is distributed during typing.

  13. The fluctuation of blood glucose, insulin and glucagon concentrations before and after insulin therapy in type 1 diabetes

    Science.gov (United States)

    Arif, Idam; Nasir, Zulfa

    2015-09-01

    A dynamical-systems model of plasma glucose, insulin and glucagon concentrations has been developed to investigate the effects of insulin therapy on blood glucose, insulin and glucagon regulations in type 1 diabetic patients. Simulation results show that the normal regulation of blood glucose concentration depends on insulin and glucagon concentrations. On type 1 diabetic case, the role of insulin on regulating blood glucose is not optimal because of the destruction of β cells in pancreas. These β cells destructions cause hyperglycemic episode affecting the whole body metabolism. To get over this, type 1 diabetic patients need insulin therapy to control the blood glucose level. This research has been done by using rapid acting insulin (lispro), long-acting insulin (glargine) and the combination between them to know the effects of insulin therapy on blood glucose, insulin and glucagon concentrations. Simulation results show that these different types of insulin have different effects on blood glucose concentration. Insulin therapy using lispro shows better blood glucose control after consumption of meals. Glargin gives better blood glucose control between meals and during sleep. Combination between lispro and glargine shows better glycemic control for whole day blood glucose level.

  14. Evaluation of intake efficiencies and associated sediment-concentration errors in US D-77 bag-type and US D-96-type depth-integrating suspended-sediment samplers

    Science.gov (United States)

    Sabol, Thomas A.; Topping, David J.

    2013-01-01

    of flume and tow tests alone. This study has three interrelated goals. First, the intake efficiencies of the older US D-77 bag-type and newer, FISP-approved US D-96-type1 depth-integrating suspended‑sediment samplers are evaluated at multiple cross‑sections under a range of actual-river conditions. The intake efficiencies measured in these actual-river tests are then compared to those previously measured in flume and tow tests. Second, other physical effects, mainly water temperature and the duration of sampling at a vertical, are examined to determine whether these effects can help explain observed differences in intake efficiency both between the two types of samplers and between the laboratory and field tests. Third, the signs and magnitudes of the likely errors in suspendedsand concentration in measurements made with both types of samplers are predicted based the intake efficiencies of these two types of depth-integrating samplers. Using the relative difference in isokinetic sampling observed between the US D-77 bag-type and D-96-type samplers during river tests, measured differences in suspended-sediment concentration in a variety of size classes were evaluated between paired equal-discharge-increment (EDI) and equal-width-increment (EWI) measurements made with these two types of samplers to determine whether these differences in concentration are consistent with the differences in concentrations expected on the basis of the 1940s FISP laboratory experiments. In addition, sequential single-vertical depth-integrated samples were collected (concurrent with velocity measurements) with the US D-96-type bag sampler and two different rigidcontainer samplers to evaluate whether the predicted errors in suspended-sand concentrations measured with the US D-96- type sampler are consistent with those expected on the basis of the 1940s FISP laboratory experiments. Results from our study indicate that the intake efficiency of the US D-96-type sampler is superior to that

  15. Osteonecrosis of the jaw: effect of bisphosphonate type, local concentration, and acidic milieu on the pathomechanism.

    Science.gov (United States)

    Otto, Sven; Pautke, Christoph; Opelz, Christine; Westphal, Ines; Drosse, Inga; Schwager, Joanna; Bauss, Frieder; Ehrenfeld, Michael; Schieker, Matthias

    2010-11-01

    Osteonecrosis of the jaw has been reported in patients receiving high doses of intravenous nitrogen-containing bisphosphonates (N-BPs) because of malignant disease. The exact pathomechanisms have been elusive and questions of paramount importance remain unanswered. Recent studies have indicated toxic effects of bisphosphonates on different cell types, apart from osteoclast inhibition. Multipotent stem cells play an important role in the processes of wound healing and bone regeneration, which seem to be especially impaired in the jaws of patients receiving high doses of N-BPs. Therefore, the aim of the present study was to investigate the effects of different bisphosphonate derivatives and dose levels combined with varying pH levels on the mesenchymal stem cells in vitro. The effect of 2 N-BPs (zoledronate and ibandronate) and 1 non-N-BP (clodronate) on immortalized mesenchymal stem cells was tested at different concentrations, reflecting 1, 3, and 6 months and 1, 3, 5, and 10 years of exposure to standard oncology doses of the 2 N-BPs and equimolar concentrations of clodronate at different pH values (7.4, 7.0, 6.7, and 6.3). Cell viability and activity were analyzed using a WST assay. Cell motility was investigated using scratch wound assays and visualized using time-lapse microscopy. Both types of bisphosphonates revealed remarkable differences. Zoledronate and ibandronate showed a dose- and pH-dependent cellular toxicity. Increasing concentrations of both N-BPs and an acidic milieu led to a significant decrease in cell viability and activity (P key role in the pathogenesis of osteonecrosis of the jaw in patients receiving high doses of N-BPs for malignant diseases. Also the potency of N-BPs might be different, suggesting a greater risk of osteonecrosis of the jaw with zoledronate. Copyright © 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  16. The effect of captopriland amlodipine on C-reactive protein concentrations in type 2 diabetic hypertensive patients

    International Nuclear Information System (INIS)

    Mahmood, I.H.

    2008-01-01

    To compare the effects of the ACE inhibitor captopril with the calcium channel blocker amlodipine on serum CRP concentrations in hypertensive type 2 diabetic patients. This is a case control study conducted in Al-Wafa Diabetic Center in Mosul. Serum CRP concentrations were measured in two groups of hypertensive type 2 diabetic patients before and after drug administration (group 1 on captopril therapy, group two on amlodipine therapy). A significant reduction of serum CRP level was demonstrated after treatment with captopril but not with amlodipine. Mean CRP concentration of the control group was statistically lower than those of captopril and amlodipine groups. The present study showed that hypertensive type 2 diabetic patients are associated with increased level of CRP and therapy with captopril but not amlodipine significantly reduced CRP, suggesting a possible anti-inflammatory action of captopril in addition to its BP lowering effects thus captopril may be regarded as the drug of choice in the treatment of BP in diabetic hypertensive patients. (author)

  17. A model used to derive hazardous waste concentration limits aiming at the reduction of toxic and hazardous wastes. Applications to illustrate the discharge of secondary categories types B and C

    International Nuclear Information System (INIS)

    Paris, P.

    1989-11-01

    This report describes a model which may be used to derive hazardous waste concentration limits in order to prevent ground water pollution from a landfill disposal. First the leachate concentration limits are determined taking into account the attenuation capacity of the landfill-site as a whole; waste concentrations are then derived by an elution model which assumes a constant ratio between liquid-solid concentrations. In the example two types of landfill have been considered and in each case concentration limits have been calculated for some hazardous substances and compared with the corresponding regulatory limits. (author)

  18. Absorber design for a Scheffler-Type Solar Concentrator

    International Nuclear Information System (INIS)

    Ruelas, José; Palomares, Juan; Pando, Gabriel

    2015-01-01

    Highlights: • Receiver and absorber design methodology based in a solar image in the focal surface. • Stirling absorber dimensions based in a solar image in the focal surface of a STSC. • Comparative study of a solar image in the focal surface from different optical model. • A Monte-Carlo ray-tracing method was used to set STSC cavity receiver aperture. - Abstract: Ray tracing software, digital close range photogrammetry and the Monte-Carlo ray-tracing method have proven to be precise and efficient measurement techniques for the assessment of the shape accuracies of solar concentrators and their components. This paper presents a new method and results for the geometric aspect of a focal image for a Scheffler-Type Solar Concentrator (STSC) using ray tracing, digital close range photogrammetry and the Monte-Carlo ray-tracing method to establish parameters that allow for the design of the most suitable absorber and receiver geometry for coupling the STSC to a Stirling engine. The results of the ray tracing software, digital close range photogrammetry and Monte-Carlo ray tracing technique in STSC are associated with a Stirling receiver. When using the method to perform simulations, we found that the most suitable solar image geometry has an elliptical shape and area of 0.0065 m 2 on average. Although this result is appropriate, the geometry of the receiver is modified to fit an absorber and cavity receiver to improve the heat transfer by radiation

  19. Relationships of mercury concentrations across tissue types, muscle regions and fins for two shark species

    KAUST Repository

    O'Bryhim, Jason R.

    2017-01-31

    Mercury (Hg) exposure poses a threat to both fish and human health. Sharks are known to bioaccumulate Hg, however, little is known regarding how Hg is distributed between different tissue groups (e.g. muscle regions, organs). Here we evaluated total mercury (THg) concentrations from eight muscle regions, four fins (first dorsal, left and right pectorals, caudal-from both the inner core and trailing margin of each fin), and five internal organs (liver, kidney, spleen, heart, epigonal organ) from two different shark species, bonnethead (Sphyrna tiburo) and silky shark (Carcharhinus falciformis) to determine the relationships of THg concentrations between and within tissue groups. Total Hg concentrations were highest in the eight muscle regions with no significant differences in THg concentrations between the different muscle regions and muscle types (red and white). Results from tissue collected from any muscle region would be representative of all muscle sample locations. Total Hg concentrations were lowest in samples taken from the fin inner core of the first dorsal, pectoral, and caudal (lower lobe) fins. Mercury concentrations for samples taken from the trailing margin of the dorsal, pectoral, and caudal fins (upper and lower lobe) were also not significantly different from each other for both species. Significant relationships were found between THg concentrations in dorsal axial muscle tissue and the fin inner core, liver, kidney, spleen and heart for both species as well as the THg concentrations between the dorsal fin trailing margin and the heart for the silky shark and all other sampled tissue types for the bonnethead shark. Our results suggest that biopsy sampling of dorsal muscle can provide data that can effectively estimate THg concentrations in specific organs without using more invasive, or lethal methods.

  20. Performance Evaluation of a Solar Adsorption Refrigeration System with a Wing Type Compound Parabolic Concentrator

    OpenAIRE

    Umair, Muhammad; Akisawa, Atsushi; Ueda, Yuki

    2014-01-01

    Simulation study of a solar adsorption refrigeration system using a wing type compound parabolic concentrator (CPC) is presented. The system consists of the wing type collector set at optimum angles, adsorption bed, a condenser and a refrigerator. The wing type collector captures the solar energy efficiently in the morning and afternoon and provides the effective temperature for a longer period of time compared to that achieved by a linear collector. The objectives of the study were to evalua...

  1. Radon and aldehyde concentrations in the indoor environment. Final report

    International Nuclear Information System (INIS)

    Moschandreas, D.J.; Rector, H.E.

    1981-04-01

    Findings regarding indoor air contaminants in the energy-efficient residence (EER) in Mt. Airy, Maryland are reported. The objectives of the study were to collect and analyze relevant air quality samples (specifically radon and aldehydes), characterize the indoor air quality with respect to radon and aldehydes, and develop relationships between air infiltration rates and contaminant levels. One-fifth of the measured formaldehyde concentrations were in the range that may cause health concerns. Although indoor temperature and relative humidity affect indoor HCHO concentration, the elevated formaldehyde concentrations were measured under very low air infiltration rates. The data show that ventilation of the indoor air space is somewhat effective in reducing high HCHO concentrations. The operation of the heat exchanger led to an increase of the air infiltration rate which in turn resulted in substantial reduction of formaldehyde concentrations. A considerable number of the collected samples of indoor air displayed radon concentrations at levels higher than 1.0 to 4.0 nCim -3 (assuming an equilibrium factor of 0.5, these radon levels would correspond to working levels above the health guidelines suggested by the US EPA for homes in Florida built on land reclaimed from phosphate mining). As in the case of indoor formaldehyde concentrations, elevated indoor concentrations are substantially reduced when the infiltration rate is increased. The data base shows that the use of the air to air heat exchanger leads to reduction of indoor radon concentration by increasing the residential ventilation rate

  2. Emergency transfusion of patients with unknown blood type with blood group O Rhesus D positive red blood cell concentrates: a prospective, single-centre, observational study.

    Science.gov (United States)

    Selleng, Kathleen; Jenichen, Gregor; Denker, Kathrin; Selleng, Sixten; Müllejans, Bernd; Greinacher, Andreas

    2017-05-01

    Emergency patients with unknown blood type usually receive O Rhesus D negative (RhD-) red blood cell concentrates until their blood group is determined to prevent RhD+ related adverse transfusion reactions. As 85% of individuals are RhD+, this consumption of O RhD- red blood cell concentrates contributes to shortages of O RhD- red blood cell concentrates, sometimes forcing transfusion of known RhD- patients with RhD+ red blood cell concentrates. Here we report the outcome of this transfusion policy transfusing all emergency patients with unknown blood type with O RhD+ red blood cell concentrates. In this prospective single-centre observational study done between Jan 1, 2001, and Dec 31, 2015, we assessed all consecutive RhD- patients at the University Medicine Greifswald who received RhD+ red blood cell concentrates (emergency patients with unknown blood type; and RhD- patients receiving RhD+ red blood cell concentrates during RhD- red blood cell concentrate shortages). No patients were excluded. The primary endpoint was anti-D allo-immunisation at 2 months follow-up or later. Patients were followed up and tested for immunisation against red blood cell antigens using the direct antiglobulin test and an antibody screen every 3-5 days for 4 weeks or until death, or hospital discharge. Surviving patients were screened for development of anti-D antibodies for up to 12 months (at the predefined timepoints 2, 3, 6, and 12 months) after RhD+ red blood cell transfusion. 437 emergency patients, of whom 85 (20%) were RhD-, received 2836 RhD+ red blood cell concentrates. The overall risk of inducing anti-D antibodies (in all 437 recipients) was 17 (4%, 95% CI 2·44-6·14) of 437 (assuming all patients lost to follow-up developed anti-D allo-immunisation). During this period, 110 known RhD- patients received RhD+ red blood cell concentrates during RhD- red blood cell concentrate shortages. Of these, 29 (26%; 95% CI 19·0-35·3) developed anti-D allo-immunisation (assuming all

  3. The relationship between serum 25-hydroxy vitamin D concentration and obesity in type 2 diabetic patients and healthy subjects

    Directory of Open Access Journals (Sweden)

    Taheri Ehsaneh

    2012-09-01

    Full Text Available Abstract Background Both obesity and type 2 diabetes are associated with hypovitaminosis D. The aims of this study were to investigate the association of serum 25-hydroxy vitamin D (25(OH D and parathyroid hormone (PTH concentration with body mass index (BMI in type 2 diabetic patients compared to control subjects and their predicting role in obesity. Methods This cross-sectional study was conducted on 200 subjects (100 type 2 diabetics and 100 healthy controls. Concentration of 25(OH D, calcium, phosphorous, parathyroid hormone (PTH, fasting blood glucose, HbA1c, serum insulin, homeostasis model assessment of insulin resistance (HOMA-IR was determined in the fasting samples. Anthropometric measurements including body mass index (BMI were also measured. Results Eighty-five percent of type 2 diabetics and 79% of healthy subjects were suffering from vitamin D deficiency or insufficiency. Serum concentration of 25(OH D (22.08 ± 15.20 ng/ml (r = −0.11, P = 0.04 and calcium (8.94 ± 0.59 mg/dl (r = −2.25, P = 0.04 has significant statistically with BMI in type 2 diabetic patients. Serum concentration of PTH has non-significantly associated with BMI in diabetic patients and healthy subjects. Conclusion Serum levels of vitamin D inversely and PTH positively are associated with BMI after adjusted for age, gender and serum calcium in both type 2 diabetic patients and healthy subjects. These associations were statistically significant for serum concentration of vitamin D and calcium only in diabetic patients. So the status of vitamin D is considered as an important factor in type 2 diabetic patients.

  4. Methods for estimating heterocyclic amine concentrations in cooked meats in the US diet.

    Science.gov (United States)

    Keating, G A; Bogen, K T

    2001-01-01

    Heterocyclic amines (HAs) are formed in numerous cooked foods commonly consumed in the diet. A method was developed to estimate dietary HA levels using HA concentrations in experimentally cooked meats reported in the literature and meat consumption data obtained from a national dietary survey. Cooking variables (meat internal temperature and weight loss, surface temperature and time) were used to develop relationships for estimating total HA concentrations in six meat types. Concentrations of five individual HAs were estimated for specific meat type/cooking method combinations based on linear regression of total and individual HA values obtained from the literature. Using these relationships, total and individual HA concentrations were estimated for 21 meat type/cooking method combinations at four meat doneness levels. Reported consumption of the 21 meat type/cooking method combinations was obtained from a national dietary survey and the age-specific daily HA intake calculated using the estimated HA concentrations (ng/g) and reported meat intakes. Estimated mean daily total HA intakes for children (to age 15 years) and adults (30+ years) were 11 and 7.0 ng/kg/day, respectively, with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) estimated to comprise approximately 65% of each intake. Pan-fried meats were the largest source of HA in the diet and chicken the largest source of HAs among the different meat types.

  5. Oro-facial-digital syndrome Type 1: A case report

    Directory of Open Access Journals (Sweden)

    Kanika Singh Dhull

    2014-01-01

    Full Text Available Oro-Facial Digital Syndrome (OFDS is a generic term for group of apparently distinctive genetic diseases that affect the development of the oral cavity, facial features, and digits. One of these is OFDS type I (OFDS-I which has rarely been reported in Asian countries. This is the case report of a 13 year old patient with OFDS type I who reported to the Department of Pedodontics and Preventive Dentistry, with the complaint of discolored upper front teeth.

  6. Comparative study of the concentration of salivary and blood glucose in type 2 diabetic patients.

    Science.gov (United States)

    Vasconcelos, Ana Carolina U; Soares, Maria Sueli M; Almeida, Paulo C; Soares, Teresa C

    2010-06-01

    The objective of the present study was to comparatively evaluate the concentrations of blood and salivary glucose as well as salivary flow and xerostomia in type 2 diabetic and non-diabetic patients. The mean salivary glucose level in diabetic patients was 14.03 +/-16.76 mg/dl and 6.35 +/- 6.02 mg/dl (P = 0.036) in the control group. The mean capillary blood glucose level in diabetic patients was 213 +/- 88 mg/dl, while that in non-diabetic patients was 99 +/- 14 mg/dl (P = 0.000). The mean value for resting salivary flow was 0.21 +/- 0.16 ml/min in diabetic patients and 0.33 +/- 0.20 ml/min in the control group (P = 0.002). The stimulated salivary flow was lower in the group of diabetic patients, with a mean of 0.63 +/- 0.43 ml/min, whereas the control group showed a mean of 1.20 +/- 0.70 ml/min (P = 0.000). Of the diabetic patients, 45% exhibited hyposalivation, in contrast to 2.5% of the non-diabetic patients (P = 0.000). Xerostomia was reported in 12.5% of diabetic patients and 5% of non-diabetic patients (P = 0.23). We can conclude that salivary glucose concentration was significantly higher in the experimental group and that there was no correlation between salivary and blood glucose concentrations in diabetic patients. The total salivary flow was significantly reduced in diabetic patients and there was no significant difference as to the presence of xerostomia in both groups.

  7. A lack of association between vitamin D-binding protein and 25-hydroxyvitamin D concentrations in pediatric type 1 diabetes without microalbuminuria

    Directory of Open Access Journals (Sweden)

    Hwa Young Kim

    2017-12-01

    Full Text Available Purpose Vitamin D deficiency is reported to be more common in type 1 diabetes patients and might be associated with the increased urinary loss of vitamin D binding protein (VDBP consequent to impaired 25-hydroxyvitamin D (25(OHD circulation. We aimed to evaluate the possible increased urinary loss of VDBP, a correlation between VDBP and circulating 25(OHD level, and risk factors influencing low vitamin D level in pediatric type 1 diabetes patients without microalbuminuria. Methods This is a cross-sectional study of subjects who visited Seoul National University Children’s Hospital between January and March 2013. Forty-two type 1 diabetes patients and 29 healthy controls were included. Biochemical parameters including serum and urine VDBP concentrations were analyzed. Results There was no significant difference in the frequency of vitamin D deficiency or serum 25(OHD level between the 2 groups. The serum and urine VDBP concentrations did not show any difference between the 2 groups. Serum 25(OH D level did not correlate with serum or urine VDBP. Multivariate regression analysis revealed that daylight outdoor hours (β=2.948, P=0.003 and vitamin D intake (β=2.865, P=0.003 affected the 25(OHD level; the presence of type 1 diabetes or urinary VDBP excretion was not significant. Conclusions In pediatric type 1 diabetes patients, urinary VDBP excretion did not contribute to low serum 25(OHD level in the setting of normoalbuminuria. The factors associated with 25(OHD level during winter periods were daylight outdoor hours and vitamin D intake. Further studies including both micro- and macroalbuminuria patients with type 1 diabetes are warranted.

  8. Chromium and cobalt ion concentrations in blood and serum following various types of metal-on-metal hip arthroplasties

    DEFF Research Database (Denmark)

    Jantzen, Christopher; Jørgensen, Henrik L; Duus, Benn R

    2013-01-01

    Widely different metal ion concentrations in blood and serum have been reported with metal-on-metal (MoM) implants. We reviewed the literature on blood and serum ion concentrations of chromium (Cr) and cobalt (Co) following various MoM hip arthroplasties.......Widely different metal ion concentrations in blood and serum have been reported with metal-on-metal (MoM) implants. We reviewed the literature on blood and serum ion concentrations of chromium (Cr) and cobalt (Co) following various MoM hip arthroplasties....

  9. [Reduced zinc concentration in expressed prostatic secretion relates to the pain symptoms of types Ⅲ and Ⅳ prostatitis].

    Science.gov (United States)

    Mo, Lin-Jian; Chen, Xi; Wang, Xiao-Ming; Li, Guang-Yu; Zhang, Xun; Huang, Shan; Xie, Zhi-Bin; Mo, Zeng-Nan

    2016-06-01

    To determine the zinc levels in the expressed prostatic secretion (EPS) of the patients with different types of chronic nonbacterial prostatitis, and explore the reference value of zinc concentration in EPS in the diagnosis and treatment of prostatitis. We collected EPS samples from 35 healthy men and 173 patients with chronic nonbacterial prostatitis, including 65 cases of type ⅢA, 69 cases of type ⅢB, and 39 cases of type Ⅳ, according to the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). We compared the zinc levels in the EPS samples among different groups and analyzed the correlations of zinc concentration with the NIH-CPSI scores, WBC count, pH value, and age of the subjects. The participants were aged 17-65 (32.5±8.5) years. The zinc concentrations in the EPS were significantly lower in the ⅢA ([162.2±10.8] μg/ml) and ⅢB ([171.2±12.0] μg/ml) than in the Ⅳ ([234.6±17.9] μg/ml) (Pprostatitis may be associated with the pain symptoms of the disease, which suggests the potential reference value of measuring the zinc concentration in EPS in the diagnosis and treatment of prostatitis.

  10. Impact of Cabin Ozone Concentrations on Passenger Reported Symptoms in Commercial Aircraft

    DEFF Research Database (Denmark)

    Bekö, Gabriel; Allen, Joseph G.; Weschler, Charles J.

    2015-01-01

    relatively low (median: 9.5 ppb). On thirteen flights (16%) ozone levels exceeded 60 ppb, while the highest peak level reached 256 ppb for a single flight. The most commonly reported symptoms were dry mouth or lips (26%), dry eyes (22.1%) and nasal stuffiness (18.9%). 46% of passengers reported at least one...... symptom related to the eyes or mouth. A third of the passengers reported at least one upper respiratory symptom. Using multivariate logistic (individual symptoms) and linear (aggregated continuous symptom variables) regression, ozone was consistently associated with symptoms related to the eyes...... and certain upper respiratory endpoints. A concentration-response relationship was observed for nasal stuffiness and eye and upper respiratory symptom indicators. Average ozone levels, as opposed to peak concentrations, exhibited slightly weaker associations. Medium and long duration flights were...

  11. Impact of hydrocarbon type, concentration and weathering on its biodegradability in soil.

    Science.gov (United States)

    Maletić, Snežana P; Dalmacija, Božo D; Rončević, Srđan D; Agbaba, Jasmina R; Perović, Svetlana D Ugarčina

    2011-01-01

    The objective of this research was to investigate the impact of the hydrocarbon type and concentration, as well as the total effect of the natural weathering process to hydrocarbon biodegradability in sandy soil and the environment. In this experiment, sandy soil was separately contaminated with 0.5%, 1.0%, 2.0% and 3.5% of diesel and crude oils. Oil contaminated soil was taken from the Oil Refinery dumping sites after 9 years of weathering, and its concentration was adjusted to the above-mentioned levels. The biodegradation process was monitored by measuring CO(2), evolution rate, hydrocarbon degradation rate and dehydrogenase activity. The favourable concentration ranges for the soil contaminated with diesel oil were 1.0%, with concentrations at about 2.0% causing slightly adverse effects to CO(2) production which was overcome after 2 weeks, and with 3.5% diesel oil causing significant toxicity. For soil contaminated with crude oil, 2.0% was found to be optimum for effective biodegradation, with 3.5% crude oil also causing adverse effects to CO(2) production, although less so than the same concentration of diesel oil. No adverse effect was obtained for any concentration of the weathered oil, as after the weathering process, the remaining contaminants in the soil were mostly poorly degradable constituents like asphaltenes, resins etc. It has been proposed that such residual material from oil degradation is analogous to, and can even be regarded as, humic material. Due to its inert characteristics, insolubility and similarity to humic materials it is unlikely to be environmentally hazardous.

  12. Heterogeneity of soil surface ammonium concentration and other characteristics, related to plant specific variability in a Mediterranean-type ecosystem

    International Nuclear Information System (INIS)

    Cruz, Cristina; Bio, Ana M.F.; Jullioti, Aldo; Tavares, Alice; Dias, Teresa; Martins-Loucao, Maria Amelia

    2008-01-01

    Heterogeneity and dynamics of eight soil surface characteristics essential for plants-ammonium and nitrate concentrations, water content, temperature, pH, organic matter, nitrification and ammonification rates-were studied in a Mediterranean-type ecosystem on four occasions over a year. Soil properties varied seasonally and were influenced by plant species. Nitrate and ammonium were present in the soil at similar concentrations throughout the year. The positive correlation between them at the time of greatest plant development indicates that ammonium is a readily available nitrogen source in Mediterranean-type ecosystems. The results presented here suggest that plant cover significantly affects soil surface characteristics. - In Mediterranean-type ecosystems ammonium is present in the soil throughout the year and its concentration is dependent on plant cover

  13. Suicidal ideation reported by adults with Type 1 or Type 2 diabetes

    DEFF Research Database (Denmark)

    Handley, T E; Ventura, A D; Browne, Jessica L

    2016-01-01

    factor for a suicide attempt, the findings have implications for healthcare professionals, pointing to the importance of adequate screening and action plans for appropriate follow-up of those reporting depression. Our findings are also indicative of the psychological toll of diabetes more generally......AIMS: To examine the prevalence and correlates of suicidal ideation (SI) in a community-based sample of adults with Type 1 or Type 2 diabetes. METHODS: Participants were 3338 adults aged 18-70 years with Type 1 diabetes (n = 1376) or Type 2 diabetes (non-insulin: n = 1238; insulin: n = 724) from...... a national survey administered to a random sample registered with the National Diabetes Services Scheme. Depression and SI were assessed using the Patient Health Questionnaire, and diabetes-specific distress with the Problem Areas In Diabetes scale. Separate logistic regression analyses by diabetes type...

  14. Measuring concentrations of selected air pollutants inside California vehicles. Final report

    International Nuclear Information System (INIS)

    Rodes, C.; Sheldon, L.; Whitaker, D.; Clayton, A.; Fitzgerald, K.

    1999-01-01

    This project measured 2-hour integrated concentrations of PM10, PM2.5, metals and a number of organic chemicals including benzene and MTBE inside vehicles on California roadways. Using continuous samplers, particle counts, black carbon, and CO were also measured. In addition to measuring in-vehicle levels, the investigators measured pollutant levels just outside the vehicle, at roadside stations, and ambient air monitoring stations. Different driving scenarios were designed to assess the effects of a number of factors on in-vehicle pollutant levels. These factors included roadway type, carpool lanes, traffic conditions, geographical locations, vehicle type, and vehicle ventilation conditions. The statewide average in-vehicle concentrations of benzene, MTBE, and formaldehyde ranged from 3--22 microg/m 3 , 3--90 microg/m 3 , and 0---22 microg/m 3 , respectively. The ranges of mean PM10 and PM2.5 in-vehicle levels in Sacramento were 20--40 microg/m 3 and 6--22 microg/m 3 , respectively. In general, pollutant levels inside or just outside the vehicles were higher than those measured at the roadside stations or the ambient air stations. In-vehicle pollutant levels were consistently higher in Los Angeles than Sacramento. Pollutant levels measured inside vehicles traveling in a carpool lane were much lower than those in the right-hand, slower lanes. Under the study conditions, factors such as vehicle type and ventilation and little effect on in-vehicle pollutant levels. Other factors, such as roadway type, freeway congestion level, and time-of-day had some influence on in-vehicle pollution levels

  15. Performance, carcass and ruminal fermentation characteristics of heifers fed concentrates differing in energy level and cereal type (corn vs. wheat)

    Energy Technology Data Exchange (ETDEWEB)

    Carrasco, C.; Carro, M.D.; Fuentetaja, A.; Medel, P.

    2017-07-01

    A total of 144 beef heifers (218 ± 26.4 kg body weight) were housed in 24 pens (6 animals each) and used in a 168-day feedlot study to evaluate the influence of cereal type and energy level on performance, carcass quality and ruminal fermentation. Four concentrates were formulated according to a 2×2 factorial arrangement of treatments, with two energy levels (1,452 vs. 1,700 kcal net energy/kg) and two main cereals (wheat vs. corn). Concentrate and straw were offered ad libitum. Concentrate intake and body weight were recorded on days 42, 84, 126 and 168. Ruminal fluid was obtained by ruminocentesis from 3 heifers per pen on days 1, 84 and 168; and carcass weight, classification and yield, were determined in the same animals. Heifers fed high-energy diets had lower intake (6.97 vs. 7.29 kg fresh matter/d; p=0.011), and lower concentrate to gain ratio (5.15 vs. 5.66 kg/kg; p=0.002) than those fed low energy concentrates, and tended (p=0.069) to be heavier along the time. Neither carcass yield and classification, nor ruminal pH, volatile fatty acids nor NH3-N concentrations were affected (p>0.050) by energy level. Total volatile fatty acids concentration tended (p=0.070) to be greater in heifers fed corn-based than wheat-based concentrates. No energy level x cereal type interactions were observed. These results indicate that high energy concentrates decreased feed intake and feed conversion but had minor effects on carcass performance. Cereal type had no effects on performance and ruminal fermentation and no interactions between cereal type and energy were detected.

  16. Performance, carcass and ruminal fermentation characteristics of heifers fed concentrates differing in energy level and cereal type (corn vs. wheat)

    International Nuclear Information System (INIS)

    Carrasco, C.; Carro, M.D.; Fuentetaja, A.; Medel, P.

    2017-01-01

    A total of 144 beef heifers (218 ± 26.4 kg body weight) were housed in 24 pens (6 animals each) and used in a 168-day feedlot study to evaluate the influence of cereal type and energy level on performance, carcass quality and ruminal fermentation. Four concentrates were formulated according to a 2×2 factorial arrangement of treatments, with two energy levels (1,452 vs. 1,700 kcal net energy/kg) and two main cereals (wheat vs. corn). Concentrate and straw were offered ad libitum. Concentrate intake and body weight were recorded on days 42, 84, 126 and 168. Ruminal fluid was obtained by ruminocentesis from 3 heifers per pen on days 1, 84 and 168; and carcass weight, classification and yield, were determined in the same animals. Heifers fed high-energy diets had lower intake (6.97 vs. 7.29 kg fresh matter/d; p=0.011), and lower concentrate to gain ratio (5.15 vs. 5.66 kg/kg; p=0.002) than those fed low energy concentrates, and tended (p=0.069) to be heavier along the time. Neither carcass yield and classification, nor ruminal pH, volatile fatty acids nor NH3-N concentrations were affected (p>0.050) by energy level. Total volatile fatty acids concentration tended (p=0.070) to be greater in heifers fed corn-based than wheat-based concentrates. No energy level x cereal type interactions were observed. These results indicate that high energy concentrates decreased feed intake and feed conversion but had minor effects on carcass performance. Cereal type had no effects on performance and ruminal fermentation and no interactions between cereal type and energy were detected.

  17. The COST733 circulation type classification software: an example for surface ozone concentrations in Central Europe

    Science.gov (United States)

    Demuzere, Matthias; Kassomenos, P.; Philipp, A.

    2011-08-01

    In the framework of the COST733 Action "Harmonisation and Applications of Weather Types Classifications for European Regions" a new circulation type classification software (hereafter, referred to as cost733class software) is developed. The cost733class software contains a variety of (European) classification methods and is flexible towards choice of domain of interest, input variables, time step, number of circulation types, sequencing and (weighted) target variables. This work introduces the capabilities of the cost733class software in which the resulting circulation types (CTs) from various circulation type classifications (CTCs) are applied on observed summer surface ozone concentrations in Central Europe. Firstly, the main characteristics of the CTCs in terms of circulation pattern frequencies are addressed using the baseline COST733 catalogue (cat 2.0), at present the latest product of the new cost733class software. In a second step, the probabilistic Brier skill score is used to quantify the explanatory power of all classifications in terms of the maximum 8 hourly mean ozone concentrations exceeding the 120-μg/m3 threshold; this was based on ozone concentrations from 130 Central European measurement stations. Averaged evaluation results over all stations indicate generally higher performance of CTCs with a higher number of types. Within the subset of methodologies with a similar number of types, the results suggest that the use of CTCs based on optimisation algorithms are performing slightly better than those which are based on other algorithms (predefined thresholds, principal component analysis and leader algorithms). The results are further elaborated by exploring additional capabilities of the cost733class software. Sensitivity experiments are performed using different domain sizes, input variables, seasonally based classifications and multiple-day sequencing. As an illustration, CTCs which are also conditioned towards temperature with various weights

  18. Deep vs shallow nature of oxygen vacancies and consequent n -type carrier concentrations in transparent conducting oxides

    Science.gov (United States)

    Buckeridge, J.; Catlow, C. R. A.; Farrow, M. R.; Logsdail, A. J.; Scanlon, D. O.; Keal, T. W.; Sherwood, P.; Woodley, S. M.; Sokol, A. A.; Walsh, A.

    2018-05-01

    The source of n -type conductivity in undoped transparent conducting oxides has been a topic of debate for several decades. The point defect of most interest in this respect is the oxygen vacancy, but there are many conflicting reports on the shallow versus deep nature of its related electronic states. Here, using a hybrid quantum mechanical/molecular mechanical embedded cluster approach, we have computed formation and ionization energies of oxygen vacancies in three representative transparent conducting oxides: In2O3 ,SnO2, and ZnO. We find that, in all three systems, oxygen vacancies form well-localized, compact donors. We demonstrate, however, that such compactness does not preclude the possibility of these states being shallow in nature, by considering the energetic balance between the vacancy binding electrons that are in localized orbitals or in effective-mass-like diffuse orbitals. Our results show that, thermodynamically, oxygen vacancies in bulk In2O3 introduce states above the conduction band minimum that contribute significantly to the observed conductivity properties of undoped samples. For ZnO and SnO2, the states are deep, and our calculated ionization energies agree well with thermochemical and optical experiments. Our computed equilibrium defect and carrier concentrations, however, demonstrate that these deep states may nevertheless lead to significant intrinsic n -type conductivity under reducing conditions at elevated temperatures. Our study indicates the importance of oxygen vacancies in relation to intrinsic carrier concentrations not only in In2O3 , but also in SnO2 and ZnO.

  19. Simple schemes for generation of W-type multipartite entangled states and realization of quantum-information concentration

    International Nuclear Information System (INIS)

    Deng-Yu, Zhang; Shi-Qing, Tang; Li-Jun, Xie; Xiao-Gui, Zhan; Yin-Hua, Chen; Feng, Gao

    2010-01-01

    We propose simple schemes for generating W-type multipartite entangled states in cavity quantum electrodynamics (CQED). Our schemes involve a largely detuned interaction of Λ-type three-level atoms with a single-mode cavity field and a classical laser, and both the symmetric and asymmetric W states can be created in a single step. Our schemes are insensitive to both the cavity decay and atomic spontaneous emission. With the above system, we also propose a scheme for realizing quantum-information concentration which is the reverse process of quantum cloning. In this scheme, quantum-information originally coming from a single qubit, but now distributed into many qubits, is concentrated back to a single qubit in only one step. (general)

  20. Borderline maintenance of erythrocyte 2,3-diphosphoglycerate concentrations in normoxic type 1 (insulin dependent) diabetic subjects.

    Science.gov (United States)

    Story, C J; Roberts, A P; Ryall, R G

    1986-02-01

    Erythrocyte 2,3-diphosphoglycerate and haemoglobin A1c concentrations were measured in 26 clinically normoxic patients with type 1 (insulin dependent) diabetes mellitus. The concentration of 2,3-diphosphoglycerate theoretically required to maintain normal erythrocyte oxygen delivery function in each subject was calculated and compared with the measured concentrations. In the majority of diabetic patients 2,3-diphosphoglycerate concentrations were sufficient to keep the erythrocyte oxygen dissociation curve within the normal range under otherwise normal blood conditions. There was, however, a minority of patients in which this was not true. It is concluded that the increased erythrocyte 2,3-diphosphoglycerate concentrations in clinically normoxic diabetic subjects are generally less than compensatory for the effect of haemoglobin A1c formation on the haemoglobin-oxygen dissociation curve.

  1. Documenting Matured Science: The BACC-Type Assessment Reports

    Science.gov (United States)

    Reckermann, M.; Omstedt, A. T.

    2016-12-01

    The BACC-type reports (BALTEX and Baltic Earth Assessment of Climate Change for the Baltic Sea region, BACC 2008 and BACC II 2015) represent an approach to assessing and making available current knowledge on regional climate change and its regional impacts on the physical, biogeochemical and biological environment (ecosystems, socio-economic sphere). The BACC assessments have originated in the BALTEX scientific research community (now Baltic Earth) and are coordinated by the International Baltic Earth Secretariat. The assessments are produced by teams of scientists from the region, led by lead authors who recruit experts from relevant topics to contribute. The report of 2015 was compiled by a different group of authors as 2008 to warrant independence of personal opinions and bias. The process is not externally funded and completely based on published scientific evidence, and not biased by political or economic interest groups. The BACC-type reports aim to bring together consolidated knowledge that has broad consensus in the scientific community, but also acknowledging issues for which contradicting opinions are found in the literature, so that no consensus can be reached ("consensus on dissensus"). An international steering committee is responsible for overlooking the process, and all manuscripts are anonymously peer-reviewed by independent international experts. Outreach to stakeholders and the public is an inherent aspect of this approach to document mature science. For the Baltic Sea, there is a close collaboration with HELCOM, the intergovernmental Baltic Marine Environment Protection Commission and the major regional science-policy interface in the Baltic Sea region. A summary for non-scientists was produced for the first BACC report and is in preparation for the second. Other BACC-type reports published are the climate report for the greater Hamburg area (published in 2011), and the NOSCCA report (North Sea Climate Change Assessment), published in 2016.

  2. EARLY TESTS OF DRUM TYPE PACKAGINGS - THE LEWALLEN REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Smith, A.

    2010-07-29

    The need for robust packagings for radioactive materials (RAM) was recognized from the earliest days of the nuclear industry. The U.S. Department of Energy (DOE) Rocky Flats Plant developed a packaging for shipment of Pu in the early 1960's, which became the U.S. Department of Transportation (DOT) 6M specification package. The design concepts were employed in other early packagings. Extensive tests of these at Savannah River Laboratory (now Savannah River National Laboratory) were performed in 1969 and 1970. The results of these tests were reported in 'Drum and Board-Type Insulation Overpacks of Shipping Packages for Radioactive Materials', by E. E. Lewallen. The Lewallen Report was foundational to design of subsequent drum type RAM packaging. This paper summarizes this important early study of drum type packagings. The Lewallen Report demonstrated the ability packagings employing drum and insulation board overpacks and engineered containment vessels to meet the Type B package requirements. Because of the results of the Lewallen Report, package designers showed high concern for thermal protection of 'Celotex'. Subsequent packages addressed this by following strategies like those recommended by Lewallen and by internal metal shields and supplemental, encapsulated insulation disks, as in 9975. The guidance provide by the Lewallen Report was employed in design of a large number of drum size packagings over the following three decades. With the increased public concern over transportation of radioactive materials and recognition of the need for larger margins of safety, more sophisticated and complex packages have been developed and have replaced the simple packagings developed under the Lewallen Report paradigm.

  3. Waste Form and Indrift Colloids-Associated Radionuclide Concentrations: Abstraction and Summary

    International Nuclear Information System (INIS)

    Aguilar, R.

    2003-01-01

    This Model Report describes the analysis and abstractions of the colloids process model for the waste form and engineered barrier system components of the total system performance assessment calculations to be performed with the Total System Performance Assessment-License Application model. Included in this report is a description of (1) the types and concentrations of colloids that could be generated in the waste package from degradation of waste forms and the corrosion of the waste package materials, (2) types and concentrations of colloids produced from the steel components of the repository and their potential role in radionuclide transport, and (3) types and concentrations of colloids present in natural waters in the vicinity of Yucca Mountain. Additionally, attachment/detachment characteristics and mechanisms of colloids anticipated in the repository are addressed and discussed. The abstraction of the process model is intended to capture the most important characteristics of radionuclide-colloid behavior for use in predicting the potential impact of colloid-facilitated radionuclide transport on repository performance

  4. Waste Form and Indrift Colloids-Associated Radionuclide Concentrations: Abstraction and Summary

    Energy Technology Data Exchange (ETDEWEB)

    R. Aguilar

    2003-06-24

    This Model Report describes the analysis and abstractions of the colloids process model for the waste form and engineered barrier system components of the total system performance assessment calculations to be performed with the Total System Performance Assessment-License Application model. Included in this report is a description of (1) the types and concentrations of colloids that could be generated in the waste package from degradation of waste forms and the corrosion of the waste package materials, (2) types and concentrations of colloids produced from the steel components of the repository and their potential role in radionuclide transport, and (3) types and concentrations of colloids present in natural waters in the vicinity of Yucca Mountain. Additionally, attachment/detachment characteristics and mechanisms of colloids anticipated in the repository are addressed and discussed. The abstraction of the process model is intended to capture the most important characteristics of radionuclide-colloid behavior for use in predicting the potential impact of colloid-facilitated radionuclide transport on repository performance.

  5. Effect of cation type and concentration of nitrates on neurological disorders during experimental cerebral ischemia.

    Science.gov (United States)

    Kuzenkov, V S; Krushinskii, A L; Reutov, V P

    2013-10-01

    Experiments were performed on the model of ischemic stroke due to bilateral occlusion of the carotid arteries. Nitrates had various effects on the dynamics of neurological disorders and mortality rate of Wistar rats, which depended on the cation type and concentration.

  6. Do different cow types respond differently to a reduction on concentrate supplementation in an Alpine low-input dairy system?

    DEFF Research Database (Denmark)

    Horn, Marco; Steinwidder, Andreas; Pfister, Rupert

    2014-01-01

    by farmers as being better suited for low-input production systems. Both genotypes were assigned to one of two concentrate supplementation levels, receiving 618 kg (Con) or 279 kg (Low) of concentrates per lactation. During two years data were collected for 21 lactations from 13 BS cows and 29 lactations...... from 20 HFL cows. No significant interactions between cow type and dietary treatment were found for most traits investigated. However, there was a tendency (Pcow type×diet=0.096) for energy-corrected-milk (ECM) yield to be reduced at the Low compared with the Con concentrate level in BS but not in HFL...

  7. Fast monitoring of indoor bioaerosol concentrations with ATP bioluminescence assay using an electrostatic rod-type sampler.

    Directory of Open Access Journals (Sweden)

    Ji-Woon Park

    Full Text Available A culture-based colony counting method is the most widely used analytical technique for monitoring bioaerosols in both indoor and outdoor environments. However, this method requires several days for colony formation. In this study, our goal was fast monitoring (Sampling: 3 min, Detection: < 1 min of indoor bioaerosol concentrations with ATP bioluminescence assay using a bioaerosol sampler. For this purpose, a novel hand-held electrostatic rod-type sampler (110 mm wide, 115 mm long, and 200 mm tall was developed and used with a commercial luminometer, which employs the Adenosine triphosphate (ATP bioluminescence method. The sampler consisted of a wire-rod type charger and a cylindrical collector, and was operated with an applied voltage of 4.5 kV and a sampling flow rate of 150.7 lpm. Its performance was tested using Staphylococcus epidermidis which was aerosolized with an atomizer. Bioaerosol concentrations were measured using ATP bioluminescence method with our sampler and compared with the culture-based method using Andersen cascade impactor under controlled laboratory conditions. Indoor bioaerosol concentrations were also measured using both methods in various indoor environments. A linear correlation was obtained between both methods in lab-tests and field-tests. Our proposed sampler with ATP bioluminescence method may be effective for fast monitoring of indoor bioaerosol concentrations.

  8. Free testosterone concentration is inversely associated with markers of liver fibrosis in men with type 2 diabetes mellitus.

    Science.gov (United States)

    Miyauchi, Shozo; Miyake, Teruki; Miyazaki, Masumi; Eguchi, Toru; Niiya, Tetsuji; Yamamoto, Shin; Senba, Hidenori; Furukawa, Shinya; Matsuura, Bunzo; Hiasa, Yoichi

    2017-12-28

    The association between serum testosterone level and liver fibrosis in patients with non-alcoholic fatty liver disease is unclear. To clarify this association, we investigated the relationship between serum free testosterone concentration and markers of liver fibrosis in men with type 2 diabetes mellitus but no obvious features of alcohol consumption. This retrospective observational cross-sectional study enrolled 248 men with type 2 diabetes mellitus. The FIB-4 index was measured as a marker of liver fibrosis, and multiple linear regression analysis was performed to examine its association with serum free testosterone concentration. In addition, the 7S domain of type IV collagen (IV-7S) was examined in 140 of the 248 patients. The mean free testosterone concentration was 10.6 ± 6.8 pg/mL and the means of the FIB-4 index and IV-7S were 1.64 ± 1.19 and 4.02 ± 1.11 ng/mL, respectively. After adjusting for all relevant variables, serum free testosterone concentrations were inversely associated with both the FIB-4 index and IV-7S (β; -0.28, P diabetes mellitus may help to predict progression to advanced liver disease. Identifying patients at risk may help to prevent the development of cirrhosis and hepatocellular carcinoma.

  9. The Role of Ownership Concentration, its Types and Firm Performance: A Quantitative Study of Financial Sector in Pakistan

    Directory of Open Access Journals (Sweden)

    Kashif Rashid

    2014-06-01

    Full Text Available The issue of ownership concentration has attracted a lot of attention in an emerging economy. The aim of this study is to investigate the impact of ownership concentration and its different types on the performance of a firm. For this purpose a panel data of 27 firms of banking and financial services sector of Pakistan listed at Karachi Stock Exchange (KSE is used as a sample for the period from 2007 to 2011. Ownership concentration and types of ownership are used as independent variables. Tobin’s Q is used as a proxy for the firm performance. The results of regression show that ownership concentration has a negative impact on the performance of a firm. Furthermore, the results of the study suggest that bigger size, individual and family ownership and bank and institutional ownership improve the value of shareholders in the selected market. The types of ownership have a positive relationship with the firm performance supporting stewardship theory. On the contrary, higher leverage and aged firms deteriorate the shareholder’s value in Pakistan. The results of incremental regression analysis show that the firm size is the most important variable in affecting the value of a firm. These results are valuable to researchers and policy makers in Pakistan.

  10. Dual curvature acoustically damped concentrating collector. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Smith, G.A.; Rausch, R.A.

    1980-05-01

    A development program was conducted to investigate the design and performance parameters of a novel, dual curvature, concentrating solar collector. The reflector of the solar collector is achieved with a stretched-film reflective surface that approximates a hyperbolic paraboloid and is capable of line-focusing at concentration ratios ranging from 10 to 20X. A prototype collector was designed based on analytical and experimental component trade-off activities as well as economic analyses of solar thermal heating and cooling systems incorporating this type of collector. A prototype collector incorporating six 0.66 x 1.22 m (2 x 4 ft) was fabricated and subjected to a limited thermal efficiency test program. A peak efficiency of 36% at 121/sup 0/C (250/sup 0/F) was achieved based upon the gross aperture area. Commercialization activities were conducted, including estimated production costs of $134.44/m/sup 2/ ($12.49/ft/sup 2/) for the collector assembly (including a local suntracker and controls) and $24.33/m/sup 2/ ($2.26/ft/sup 2/) for the reflector subassembly.

  11. Correlation of serum 25(OHVitD concentration with metabolism parameters in patients with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Yuan-Qing Qu

    2016-04-01

    Full Text Available Objective: To explore the correlation of serum 25(OHVitD concentration with the metabolism parameters in patients with type 2 diabetes. Methods: A total of 80 patients with type 2 diabetes who were admitted in our hospital from January, 2014 to March, 2015 were included in the study and served as the observation group, while 80 healthy individuals who came our hospital for physical examination were served as the control group. The serum 25(OHVitD concentration and metabolism parameters in the two groups were detected. The correlation of serum 25(OHVitD concentration with the metabolism parameters was analyzed. Results: The body weight, height, and BMI in the observation group were significantly higher than those in the control group (P0.05. The serum 25(OHVitD and HDL-C levels in the observation group were significantly lower than those in the control group (P<0.05, while SBP, FBG, TG, and DBP levels were significantly higher than those in the control group (P<0.05. The serum 25(OHVitD was negatively correlated with body weight, BMI, abdominal circumference, SBP, DBP, FBG, LDL-C, TG, and HbAlc. Conclusions: The serum 25(OHVitD level is closely associated with TG, LDL-C, and HbAlc, providing a reference value for the study on type 2 diabetes.

  12. Inverse association between plasma homocysteine concentrations and type 2 diabetes mellitus among a middle-aged and elderly Chinese population.

    Science.gov (United States)

    Yu, C; Wang, J; Wang, F; Han, X; Hu, H; Yuan, J; Miao, X; Yao, P; Wei, S; Wang, Y; Liang, Y; Chen, W; Zhang, X; Guo, H; Yang, H; Tang, Y; Zheng, D; Wu, T; He, M

    2018-03-01

    Plasma homocysteine concentrations have been reported to be associated with type 2 diabetes mellitus (T2DM) with controversial findings. The aim of the present study was to investigate the association between plasma homocysteine concentrations and T2DM. A cross-sectional study including 19,085 eligible participants derived from the Dongfeng-Tongji cohort was conducted. Plasma homocysteine concentrations were measured by Abbott Architect i2000 Automatic analyzer and T2DM was defined according to American Diabetes Association criteria. Logistic regression model was used to explore the association between plasma homocysteine concentrations and T2DM. The prevalence of T2DM was 19.0% in the whole population (mean age 62.9 years), 21.8% in males, and 17.1% in females. In the multivariable logistic regression analyses, compared with those in the lowest quintile, the OR (95% CI) of T2DM was 1.05 (0.92-1.21), 0.99 (0.86-1.14), 0.90 (0.78-1.05), and 0.77 (0.66-0.90) for quintile 2 to quintile 5 of homocysteine concentrations after adjustment for potential confounders (P for trend associated with decreased T2DM prevalence risk (OR = 0.88 per SD increase of homocysteine concentration; 95% CI: 0.84-0.93). A significant interaction between homocysteine concentrations and drinking status on T2DM prevalence risk was observed (P for interaction = 0.03). The inverse association of plasma homocysteine concentrations with T2DM prevalence risk was observed in non-drinkers but not in current drinkers. Plasma homocysteine concentrations were inversely correlated with T2DM among a middle-aged and elderly Chinese population. Copyright © 2017 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

  13. Relationship between serum bilirubin concentrations and diabetic nephropathy in Shanghai Han's patients with type 1 diabetes mellitus.

    Science.gov (United States)

    Li, Xu; Zhang, Lei; Chen, Haibing; Guo, Kaifeng; Yu, Haoyong; Zhou, Jian; Li, Ming; Li, Qing; Li, Lianxi; Yin, Jun; Liu, Fang; Bao, Yuqian; Han, Junfeng; Jia, Weiping

    2017-03-31

    Recent studies highlight a negative association between total bilirubin concentrations and albuminuria in patients with type 2 diabetes mellitus. Our study evaluated the relationship between bilirubin concentrations and the prevalence of diabetic nephropathy (DN) in Chinese patients with type 1 diabetes mellitus (T1DM). A total of 258 patients with T1DM were recruited and bilirubin concentrations were compared between patients with or without diabetic nephropathy. Multiple stepwise regression analysis was used to examine the relationship between bilirubin concentrations and 24 h urinary microalbumin. Binary logistic regression analysis was performed to assess independent risk factors for diabetic nephropathy. Participants were divided into four groups according to the quartile of total bilirubin concentrations (Q1, 0.20-0.60; Q2, 0.60-0.80; Q3, 0.80-1.00; Q4, 1.00-1.90 mg/dL) and the chi-square test was used to compare the prevalence of DN in patients with T1DM. The median bilirubin level was 0.56 (interquartile: 0.43-0.68 mg/dL) in the DN group, significantly lower than in the non-DN group (0.70 [interquartile: 0.58-0.89 mg/dL], P 1). Spearman's correlational analysis showed bilirubin concentrations were inversely correlated with 24 h urinary microalbumin (r = -0.13, P 1.90% to 2.00%. High bilirubin concentrations are independently and negatively associated with albuminuria and the prevalence of DN in patients with T1DM.

  14. The serum concentration of copper in bipolar disorder.

    Science.gov (United States)

    Siwek, Marcin; Styczeń, Krzysztof; Sowa-Kućma, Magdalena; Dudek, Dominika; Reczyński, Witold; Szewczyk, Bernadeta; Misztak, Paulina; Opoka, Włodzimierz; Topór-Mądry, Roman; Nowak, Gabriel; Rybakowski, Janusz K

    2017-06-18

    Some scientific reports indicate the changes in the concentration of serum copper in patients with bipolar disorder (BD), however the data are inconclusive. The aim of this study was to assess the concentration of copper in the blood serum of patients in various phases of BD compared to healthy volunteers, taking into consideration the specific clinical features, and the stage of illness. The study enrolled 133 patients with a diagnosis of BD (type I, II and NOS), including 61 people in depressive episode, 23 in mania or hypomania and 49 in remission. The control group consisted of 50 people. Atomic absorption spectrometry was used to measure the concentration of copper. There were no statistically significant differences in the serum copper concentration between patients in various phases of BD (mania/hypomania, depression, remission), sub-types (Type I, Type II + NOS) or stages and healthy volunteers. However, serum copper concentrations in patients in stage 1 was significantly higher than in advanced stages (2+3+4), (ß = 0.22; p = 0.02). Serum copper concentration was also the higher, the later the age of onset was (ß = 0.33; p < 0.001), and the lower, the greater the number of illness episodes (ß = - 0.23; p = 0.02) (multiple regression model, adj R2 = 0.19, p = 0.0001). The dependencies demonstrated above may reflect pathophysiological processes that occur in the course of BD (e.g., inflammatory response and oxidative stress) with a different intensity depending on its stage.

  15. Effect of catchment land use and soil type on the concentration, quality, and bacterial degradation of riverine dissolved organic matter

    DEFF Research Database (Denmark)

    Autio, Iida; Soinne, Helena; Helin, Janne

    2016-01-01

    We studied the effects of catchment characteristics (soil type and land use) on the concentration and quality of dissolved organic matter (DOM) in river water and on the bacterial degradation of terrestrial DOM. The share of organic soil was the strongest predictor of high concentrations...... of dissolved organic carbon, nitrogen, and phosphorus (DOC, DON, and DOP, respectively), and was linked to DOM quality. Soil type was more important than land use in determining the concentration and quality of riverine DOM. On average, 5–9 % of the DOC and 45 % of the DON were degraded by the bacterial...

  16. 137Cs concentration distribution in among feeds and various soil types

    International Nuclear Information System (INIS)

    Csupka, S.

    1980-01-01

    The distribution of 137 Cs in four types of arable land and soil with grass cover (chernozem, serozem, gely soddy soil and meadow calcareous soil) is different. In arable land the penetration of 137 Cs into greater depths is higher than under the grasscover, where the main proportion of 137 Cs is retained by the upper layers in the depth of 0 to 5 cm. The only exception is gley soddy soil, where the upper layers allow the passage of radionuclides into greater depths. In the soil horizon to a depth of 50 cm out or the total content of 137 Cs from 16 to 47% is bound in exchangeable form and from 53 to 84% in a form available to plants according to the soil type. The relationship between exchangeable 137 Cs and that available to plants in soils is given by the coefficient of desorption and the relation between the 137 Cs content in the plant and in the soil is given by the coefficient of concentration. Their value varies within the range of 0.1 to 2.6. (author)

  17. No evidence for increased self-reported cognitive failure in Type 1 and Type 2 diabetes

    DEFF Research Database (Denmark)

    Wessels, A M; Pouwer, F; Geelhoed-Duijvestijn, P H L M

    2007-01-01

    in adult out-patients with Type 1 and Type 2 diabetes. METHODS: Subjective cognitive functioning was measured in 187 diabetic patients using the Cognitive Failures Questionnaire (CFQ). Demographic and clinical characteristics were retrieved from the medical records. The Patient Health Questionnaire 9 items...... (PHQ-9) was self-administered along with the CFQ to correct for the confounding effect of depression. RESULTS: Analyses were based on 55 patients with Type 1 diabetes and 100 patients with Type 2 diabetes. No difference in mean CFQ score was observed between Type 1 and Type 2 diabetic patients...... or between Type 1 diabetic patients and healthy control subjects. Female patients with Type 2 diabetes reported significantly fewer cognitive complaints compared with female healthy control subjects. None of the demographic variables and diabetes-related complications was associated with subjective cognitive...

  18. Plasma concentrations of VCAM-1 and ICAM-1 are elevated in patients with Type 1 diabetes mellitus with microalbuminuria and overt nephropathy

    DEFF Research Database (Denmark)

    Clausen, P; Jacobsen, P; Rossing, K

    2000-01-01

    AIMS: Elevated urinary albumin excretion is associated with macrovascular atherosclerotic complications in Type 1 diabetes mellitus. Adhesion molecules mediate leucocyte adhesion to the endothelium early in the atherosclerotic process. The present study tests the hypothesis that microalbuminuria...... disease in diabetic patients with renal complications. METHODS: Soluble adhesion molecule concentrations were measured by enzyme-linked immunosorbent assays (ELISA) in healthy controls (n = 16) and in 59 Type 1 diabetic patients: group 1-patients with normoalbuminuria (n = 16); group 2-patients...... diabetic patients, but the concentrations were increased by the presence of microalbuminuria and overt nephropathy (P diabetic patients and controls. CONCLUSIONS: Plasma concentration of sICAM-1 is elevated in Type 1...

  19. Relationship between the serum concentrations of C-reactive protein and parameters of adiposity and insulin resistance in patients with type 2 diabetes mellitus

    International Nuclear Information System (INIS)

    Iwasaki, Tomoyuki; Nakajima, Atsushi; Yoneda, Masato; Terauchi, Yasuo

    2006-01-01

    Serum C-reactive protein (CRP) concentrations have been reported to be associated with body fat, especially visceral fat accumulation, but most studies up to now have been conducted on non-diabetic subjects. In this study, we investigated the association between the serum CRP concentrations and parameters of adiposity and insulin resistance in both Japanese type 2 diabetes patients and non-diabetic subjects. A total of 248 Japanese subjects (140 type 2 diabetes patients and 108 non-diabetic subjects) were enrolled for the study. The degree of insulin resistance was estimated by the homeostasis model assessment (HOMA-R) method. Fat accumulation was evaluated by measuring visceral and subcutaneous fat areas at the level of the umbilicus in abdominal CT scans. To assess hepatic fat content, the ratio of CT attenuation value of the liver to that of the spleen (L/S ratio) was calculated. Serum CRP was found to be significantly correlated with various indices of adiposity, including L/S ratio, visceral fat area (VFA), subcutaneous fat area (SFA), and HOMA-R, in both the diabetic patients and the non-diabetic subjects. After adjustment for five variables (age, gender, serum CRP, HbAlc, and smoking), serum CRP was still significantly correlated with L/S ratio, VFA, SFA, and HOMA-R in the diabetic patients. We also found that changes in serum CRP concentrations were correlated with changes in the VFA and SFA at 1 year after the baseline in 24 diabetic patients. We conclude that serum CRP may be closely related to the degree of liver steatosis and visceral fat accumulation in Japanese type 2 diabetes mellitus patients. (author)

  20. The Effect of Different Types of Musculoskeletal Injuries on Blood Concentration of Serum Amyloid A in Thoroughbred Racehorses

    Science.gov (United States)

    Turło, Agnieszka; Cywińska, Anna; Czopowicz, Michał; Witkowski, Lucjan; Niedźwiedź, Artur; Słowikowska, Malwina; Borowicz, Hieronim; Jaśkiewicz, Anna; Winnicka, Anna

    2015-01-01

    Background Training-induced muscle, skeletal and joint trauma may result in acute phase response reflected by the changes in the blood concentration of serum amyloid A (SAA) in racehorses. It remains yet unclear if such systemic reaction could be triggered by sport injuries and what is the impact of different types of musculoskeletal trauma on SAA concentrations in racehorses. This study aimed to determine changes in the SAA blood concentration in racehorses with different types of injuries of musculoskeletal system. Materials and Methods The study involved 28 racehorses diagnosed after the race with bone fractures (n = 7), dorsal metacarpal disease (n = 11), joint trauma (n = 4) or tendon and muscle trauma (n = 6) and 28 healthy control racehorses. Serum samples were collected twice, between 1 and 4 days of the injury or succesful completion of the race. SAA concentration was measured using the commercial ELISA kit. Differences between mean SAA concentration in respective groups were analyzed using ANOVA and Tukey post-hoc test. Results Mean SAA concentration within the first 4 days of the injury of muscle and tendon was significantly higher than in bone fractures, dorsal metacarpal disease, joint trauma or in the healthy horses (p<0,001). There were no significant differences between the other groups. Conclusions Strain injuries of muscle and tendons can cause a moderate increase in SAA blood concentration in racehorses, reflecting the occurrence of the acute phase response. Similar reaction is not observed in the stress-related bone injuries. PMID:26466121

  1. The Effect of Different Types of Musculoskeletal Injuries on Blood Concentration of Serum Amyloid A in Thoroughbred Racehorses.

    Directory of Open Access Journals (Sweden)

    Agnieszka Turło

    Full Text Available Training-induced muscle, skeletal and joint trauma may result in acute phase response reflected by the changes in the blood concentration of serum amyloid A (SAA in racehorses. It remains yet unclear if such systemic reaction could be triggered by sport injuries and what is the impact of different types of musculoskeletal trauma on SAA concentrations in racehorses. This study aimed to determine changes in the SAA blood concentration in racehorses with different types of injuries of musculoskeletal system.The study involved 28 racehorses diagnosed after the race with bone fractures (n = 7, dorsal metacarpal disease (n = 11, joint trauma (n = 4 or tendon and muscle trauma (n = 6 and 28 healthy control racehorses. Serum samples were collected twice, between 1 and 4 days of the injury or succesful completion of the race. SAA concentration was measured using the commercial ELISA kit. Differences between mean SAA concentration in respective groups were analyzed using ANOVA and Tukey post-hoc test.Mean SAA concentration within the first 4 days of the injury of muscle and tendon was significantly higher than in bone fractures, dorsal metacarpal disease, joint trauma or in the healthy horses (p<0,001. There were no significant differences between the other groups.Strain injuries of muscle and tendons can cause a moderate increase in SAA blood concentration in racehorses, reflecting the occurrence of the acute phase response. Similar reaction is not observed in the stress-related bone injuries.

  2. [A case of IgA2-lambda type M-protein that IgA concentration differs from the values of M-protein by serum protein electrophoresis].

    Science.gov (United States)

    Fukushima, M; Sugano, M; Ichikawa, T; Honda, T; Totsuka, M; Katsuyama, T; Fujita, K

    2001-07-01

    We report an IgA-lambda type M-protein in which the IgA concentration differed from the values of M-protein by serum protein electrophoresis found in a 53-year-old man with multiple myeloma. The M-protein value as determined by serum protein electrophoresis was 6,170 mg/dl. However, the serum IgA concentration was 3,052 mg/dl by turbidimetric immunoassay. Immuno-fixation electrophoresis using IgA subclass antisera revealed that this M-protein was the IgA2-lambda type. Western blotting analysis showed that the IgA2 molecules were composed of two approximately 68 kDa alpha 2 chains and two 28 kDa lambda chains. In addition the free lambda chain band was detected at the position of 28 kDa without 2-mercaptoethanol(2-ME) even though the patient IgA was purified. Since it is known that IgA2m(1) allotype easily release light chains from the IgA molecules in SDS-PAGE without 2-ME, we speculated that in this patient the IgA was the IgA2m(1) allotype. After peripheral blood stem cell transplantation(PBSCT), immunofixation electrophoresis of the patient serum revealed not only the bands of IgA2-lambda type M-protein, but also three bands of IgG1-kappa type M-protein in the gamma region.

  3. Physicochemical properties of sugar palm starch film: Effect of concentration and plasticizer type

    Science.gov (United States)

    Prasetyo, D. J.; Apriyana, W.; Jatmiko, T. H.; Hernawan; Hayati, S. N.; Rosyida, V. T.; Pranoto, Y.; Poeloengasih, C. D.

    2017-07-01

    In order to find the best formula for capsule shell production, this present work dealt with exploring physicochemical properties of sugar palm (Arenga pinnata) starch film as a function of different kinds and various concentrations of plasticizers. The films were prepared by casting method at different formula: starch 9-11%, glycerol or sorbitol 35-45% and polyethylene-glycol 400 (PEG 400) 5-9%. Appearance, thickness, retraction ratio, moisture content, swelling behavior and solubility of the film in water were analyzed. Both glycerol and sorbitol are compatible with starch matrix. On the contrary, PEG 400 did not form a film with suitable characteristics. The result reveals that glycerol- and sorbitol-plasticized films appeared translucent, homogenous, smooth and slightly brown in all formulas. Different type and concentration of plasticizers altered the physicochemical of film in different ways. The sorbitol-plasticized film had lower moisture content (≤ 10%) than that of glycerol-plasticized film (≥ 18%). In contrast, film plasticized with sorbitol showed higher solubility in water (28-35%) than glycerol-plasticized film (22-28%). As the concentration of both plasticizers increased, there was an increasing tendency on thickness and solubility in water. Conversely, retraction ratio and swelling degree decreased when both plasticizers concentration increased. In conclusion, the sorbitol-plasticized film showed a potency to be developed as hard capsule material.

  4. Volatile flavor analysis and sensory evaluation of custard desserts varying in type and concentration of carboxymethyl cellulose.

    Science.gov (United States)

    van Ruth, Saskia M; de Witte, Leontien; Uriarte, Amaya Rey

    2004-12-29

    The influence of type and concentration of carboxymethyl cellulose (CMC) on flavor and textural properties of custard desserts was examined. A synthetic strawberry flavor mixture was used to flavor the custards; it comprised 15 volatile flavor compounds. The viscosity of the custards was determined using rheometric measurements. Static headspace gas chromatography and in-nose proton transfer reaction-mass spectrometry analyses were conducted to determine the custards' volatile flavor properties. Perceived odor, flavor, and textural properties were assessed in sensory analysis experiments using magnitude estimation against a fixed modulus. Both type and concentration of CMC altered the viscosity of the custards. Softer custards had higher static headspace flavor concentrations. On the contrary, firmer custards demonstrated higher in-nose flavor concentrations. In sensory analysis, firmer custards showed higher thickness and lower sweetness intensities than their low-viscosity counterparts. The thickness perception corresponded to the viscosity of the custards. Removal of sucrose from the custards affected sweetness intensity only and not the intensity of other attributes. Therefore, the influence of the viscosity of the custards on the release of sweet-tasting components is held responsible for the effect on perceived sweetness intensity. Odor intensities were generally higher for the low-viscosity custard, whereas fruity flavor intensities were higher for the firmer custards. Odor intensities correlated with static headspace concentrations and flavor intensities related reasonably well with in-nose concentrations. Opening and closing of the nasal cavity is regarded as an important factor determining the discrepancy between static and in-nose measurements.

  5. Validity of Self-Reported Concentration and Memory Problems: Relationship with Neuropsychological Assessment and Depression

    Science.gov (United States)

    Background: This study investigated the validity of self-reported concentration and memory problems (CMP) in residents environmentally exposed to manganese (Mn). Method: Self-report of CMP from a health questionnaire (HQ) and the Symptoms Checklist-90-Revised (SCL-90-R) was com...

  6. Development of a prototype lignin concentration sensor. Final report. Draft

    Energy Technology Data Exchange (ETDEWEB)

    Jeffers, L.A.

    1994-11-01

    The ultimate objective of the DOE-sponsored program discussed in this report is to commercialize an instrument for real-time, in-situ measurement of lignin in wood pulp at a variety of locations in the pulp process stream. The instrument will be used as a primary sensor for process control in the pulp and paper industry. Work done by B&W prior to the initiation of this program had shown: there is a functional relationship between the fluorescence intensity and the Kappa number as measured at the pulp mill laboratory. Kappa number is a standard wet chemical method for determination of the lignin concentration; the relationship is one of decreasing intensity with Kappa number, indicating operation in the quenched fluorescence regime; a great deal of scatter in the data. Because of the preliminary nature of the study, the origin of the scatter was not identified. This report documents the results of laboratory measurements made on a variety of well defined pulp samples to generate the data necessary to: determine the feasibility of an instrument for on-line lignin concentration measurement using laser fluorescence; identify the preferred measurement strategy; define the range of applicability of the instrument; and to provide background information to guide the design of a field-worthy prototype.

  7. Plasma N-terminal pro B-type natriuretic peptide concentrations in dogs with pulmonic stenosis.

    Science.gov (United States)

    Kobayashi, Keiya; Hori, Yasutomo; Chimura, Syuuichi

    2014-06-01

    The detailed information between plasma N-terminal pro B-type natriuretic peptide (NT-proBNP) concentrations and dogs with pulmonic stenosis (PS) is still unknown. The aim of the present study was to investigate the clinical utility of measuring plasma NT-proBNP concentrations in dogs with PS and to determine whether plasma NT-proBNP concentration could be used to assess disease severity. This retrospective study enrolled 30 client-owned, untreated dogs with PS (asymptomatic [n=23] and symptomatic [n=7]) and 11 healthy laboratory beagles. Results of physical examination, thoracic radiography and echocardiography were recorded. Plasma NT-proBNP concentrations were measured using commercial laboratories. Compared to the healthy control dogs, cardiothoracic ratio was significantly increased in dogs with both asymptomatic and symptomatic PS. Similarly, the ratio of the main pulmonary artery to aorta was significantly decreased in dogs with both asymptomatic and symptomatic PS. The pulmonic pressure gradient in the symptomatic PS dogs was significantly higher than that in the asymptomatic PS dogs. Plasma NT-proBNP concentration was significantly elevated in the symptomatic PS dogs compared to the healthy control dogs and the asymptomatic PS dogs. Furthermore, the Doppler-derived pulmonic pressure gradient was significantly correlated with the plasma NT-proBNP concentration (r=0.78, r(2)=0.61, P764 pmol/l to identify severe PS had a sensitivity of 76.2% and specificity of 81.8%. The plasma NT-proBNP concentration increased by spontaneous PS, i.e. right-sided pressure overload and can be used as an additional method to assess the severity of PS in dogs.

  8. Evaluation of Intake Efficiencies and Associated Sediment-Concentration Errors in US D-77 Bag-Type and US D-96-Type Depth-Integrating Suspended-Sediment Samplers

    Science.gov (United States)

    Sabol, T. A.; Topping, D. J.; Griffiths, R. E.

    2011-12-01

    Accurate measurements of suspended-sediment concentration require suspended-sediment samplers to operate isokinetically with an intake-efficiency of 1.0 ± 0.10. Results from 1940s Federal Interagency Sedimentation Project (FISP) laboratory experiments show that when the intake efficiency does not equal 1.0, suspended-sediment samplers either under- or oversample sediment relative to water, leading to biases in suspended-sediment concentration. The majority of recent FISP sampler development and testing has been conducted under uniform flow conditions using flume and slack-water tow tests, with little testing in actual turbulent rivers. Recent work has focused on the hydraulic characteristics and intake efficiencies of these samplers, without field investigations of the accuracy of the suspended-sediment data collected with these samplers. When depth-integrating suspended-sediment samplers are deployed under the non-uniform and turbulent conditions that exist in rivers, multiple factors may contribute to departures from isokinetic sampling. This introduces errors into the suspended-sediment data that may not be predictable on the basis of flume and tow tests alone. This study (1) evaluates the intake efficiencies of the older US D-77 bag-type and newer, FISP-approved US D-96 samplers at multiple river cross sections under a range of flow conditions; (2) examines if water temperature and sampling duration explain measured differences in intake efficiency between samplers and between laboratory and field tests; (3) models and predicts the directions and magnitudes of errors in measured suspended-sand concentration; and (4) determines if the relative differences in suspended-sediment concentration in a variety of size classes are consistent with the differences expected on the basis of the 1940s FISP-laboratory experiments. Results indicate that under river conditions, the intake efficiency of the US D-96 sampler is superior to that of the US D-77 bag-type sampler and

  9. Tacrolimus interaction with nafcillin resulting in significant decreases in tacrolimus concentrations: A case report.

    Science.gov (United States)

    Wungwattana, Minkey; Savic, Marizela

    2017-04-01

    Tacrolimus (TAC) is subject to many drug interactions as a result of its metabolism primarily via CYP450 isoenzyme 3A4. Numerous case reports of TAC and CYP3A4 inducers and inhibitors have been described including antimicrobials, calcium channel antagonists, and antiepileptic drugs. We present the case of a 13-year-old patient with cystic fibrosis and a history of liver transplantation, where subtherapeutic TAC concentrations were suspected to be a result of concomitant TAC and nafcillin (NAF) therapy. The observed drug interaction occurred on two separate hospital admissions, during both of which the patient exhibited therapeutic TAC concentrations prior to exposure to NAF, a CYP3A4 inducer. Upon discontinuation of NAF, TAC concentrations recovered in both instances. This case represents a drug-drug interaction between TAC and NAF that has not previously been reported to our knowledge. Despite the lack of existing reports of interaction between these two agents, this case highlights the importance of therapeutic drug monitoring and assessing for any potential drug-drug or drug-food interactions in patients receiving TAC therapy. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Plasma Progranulin Concentrations Are Increased in Patients with Type 2 Diabetes and Obesity and Correlated with Insulin Resistance

    Directory of Open Access Journals (Sweden)

    Hua Qu

    2013-01-01

    Full Text Available Insulin resistance (IR is considered to be one of the most important pathogenesis of glycolipid metabolism disorders. However, the molecular mechanism responsible for IR is not fully understood. Recently, the chronic inflammation has been proposed to be involved in the pathogenesis of IR. In this study, we aim to investigate the concentrations of plasma progranulin in Chinese patients with obesity (OB and type 2 diabetes mellitus (T2DM, and its relationship to IR. Plasma progranulin concentrations were significantly higher in the T2DM patients than in the normal glucose tolerant (NGT subjects (. Within the T2DM and the NGT patients, the concentrations of progranulin were significantly higher in obese subjects than that in the normal weight subjects (225.22 ± 34.39 ng/mL versus 195.59 ± 50.47 ng/mL and 183.79 ± 61.63 ng/mL versus 148.69 ± 55.27 ng/mL, . Plasma progranulin concentrations correlated positively with weight, waist circumferences, BMI, HbA1c, TG, IL-6, FINS and HOMA-IR (, while correlated negatively with HOMA-β (. Multiple linear regression analysis showed that BMI, HbA1c, IL-6 and TG correlated independently with circulating progranulin concentrations (. These results suggested that Plasma progranulin concentrations were higher in Chinese patients with type 2 diabetes and obesity and correlated closely with glycolipid metabolism, chronic inflammation and IR.

  11. Hyperthyroidism from autoimmune thyroiditis in a man with type 1 diabetes mellitus: a case report

    Directory of Open Access Journals (Sweden)

    Hirsch Irl B

    2011-07-01

    Full Text Available Abstract Introduction The presentation, diagnosis, clinical course and treatment of a man with hyperthyroidism secondary to autoimmune thyroiditis in the setting of type 1 diabetes mellitus has not previously been described. Case presentation A 32-year-old European-American man with an eight-year history of type 1 diabetes mellitus presented with an unintentional 22-pound weight loss but an otherwise normal physical examination. Laboratory studies revealed a suppressed thyroid-stimulating hormone concentration and an elevated thyroxine level, which are consistent with hyperthyroidism. His anti-thyroid peroxidase antibodies were positive, and his thyroid-stimulating immunoglobulin test was negative. Uptake of radioactive iodine by scanning was 0.5% at 24 hours. The patient was diagnosed with autoimmune thyroiditis. Six weeks following his initial presentation he became clinically and biochemically hypothyroid and was treated with thyroxine. Conclusion This report demonstrates that autoimmune thyroiditis presenting as hyperthyroidism can occur in a man with type 1 diabetes mellitus. Autoimmune thyroiditis may be an isolated manifestation of autoimmunity or may be part of an autoimmune polyglandular syndrome. Among patients with type 1 diabetes mellitus who present with hyperthyroidism, Graves' disease and other forms of hyperthyroidism need to be excluded as autoimmune thyroiditis can progress quickly to hypothyroidism, requiring thyroid hormone replacement therapy.

  12. Imaging Finding of Multiple Endocrine Neoplasia Type 1: Case Report

    International Nuclear Information System (INIS)

    Yum, Tae Jun; Cho, Hee Woo

    2012-01-01

    Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant inherited syndrome with characteristic clinical and radiological manifestations. Many reports on MEN1 have been published; however, no cases of radiologically diagnosed MEN1 have been reported. Therefore, we report on a radiologically diagnosed case of MEN1 with clinical symptoms of gastroduodenal ulcer.

  13. Benzonphenone-type UV filters in urine of Chinese young adults: Concentration, source and exposure

    International Nuclear Information System (INIS)

    Gao, Chong-jing; Liu, Li-yan; Ma, Wan-li; Zhu, Ning-zheng; Jiang, Ling; Li, Yi-Fan; Kannan, Kurunthachalam

    2015-01-01

    Benzophenone (BP)-type UV filters are commonly used in our daily life. 2-hydroxy-4-methoxy benzophenone (BP-3), 4-hydroxy benzophenone (4-HBP), 2,4-dihydroxy benzophenone (BP-1), 2,2′,4,4′-tetrahydroxy benzophenone (BP-2) and 2,2′-dihydroxy-4-methoxy benzophenone (BP-8) were measured in urine samples from Chinese young adults. The results indicated that Chinese young adults were widely exposed to BP-3, BP-1, and 4-HBP, with the median concentrations of 0.55, 0.21, and 0.08 ng/mL, respectively. No significant difference was found between males and females, between urban and rural population. The correlations between urinary concentrations provided important indications for sources and metabolic pathways of target compounds. The estimated daily excretion doses of BP-3, 4-HBP, BP-1, BP-2 and BP-8 were 27.2, 2.24, 5.86, 0.76 and 0.30 ng/kg-bw/day, respectively. The ratio of exposure to excretion must be considered for the exposure assessment with chemicals based on urine measurement. This is the first nationwide study on BP-derivatives with young adults in China. - Highlights: • Five BP-derivatives in urine were analyzed for Chinese young adults over China. • No difference was found between males and females, between urban and rural groups. • Concentration correlation provide indications for sources and metabolic pathways. • Ratio of exposure to excretion must be considered for the exposure assessment. - Benzophenone (BP)-type UV filters were frequently detected in urine samples from Chinese young adults, indicating their wide applications in China

  14. Investigation on residential radon concentration in Jingchuan county

    International Nuclear Information System (INIS)

    Zhang Wei; Wan Yihong; Chen Hongxiao; Shang Bin

    2009-01-01

    This paper reports an investigated result of residential radon concentration in Jingchuan County, Gansu Province, during May 2004 to November 2006. Alpha track detectors were used to measure radon level. Construction types of house and percentages of residents living in the county were also investigated through questionnaires. The result showed that the mean radon concentration in 62 investigated houses was 96.2 Bq·m -3 . The radon concentration in cave dwelling was the highest among all type of dwellings. The average level in cave dwelling is 110.2 Bq·m -3 , which was significantly higher than the national mean value published in literatures, and exceed the WHO recommended value of 100 Bq·m -3 . A considerable number of rural residents are living in cave dwellings in Jingchuan County. Attention should be paid to the radon problem and some proper protection measures taken. (authors)

  15. Performance Evaluation of a Solar Adsorption Refrigeration System with a Wing Type Compound Parabolic Concentrator

    Directory of Open Access Journals (Sweden)

    Muhammad Umair

    2014-03-01

    Full Text Available Simulation study of a solar adsorption refrigeration system using a wing type compound parabolic concentrator (CPC is presented. The system consists of the wing type collector set at optimum angles, adsorption bed, a condenser and a refrigerator. The wing type collector captures the solar energy efficiently in the morning and afternoon and provides the effective temperature for a longer period of time compared to that achieved by a linear collector. The objectives of the study were to evaluate the system behavior, the effect of wing length, and to compare the performance of the systems with wing type and linear CPCs. A detailed dynamic simulation model was developed based on mass and energy balance equations. The simulation results show that the system performance with wing type CPC increases by up to 6% in the summer and up to 2% in the winter, compared to the performance with a linear CPC having same collector length. The ice production also increases up to 13% in the summer with the wing type CPC. This shows that the wing type CPC is helpful to increase the performance of the system compared to the linear CPC with the same collector length and without the need for tracking.

  16. Characterization of void volume VOC concentration in vented TRU waste drums - an interim report

    International Nuclear Information System (INIS)

    Liekhus, K.J.

    1994-09-01

    A test program is underway at the Idaho National Engineering Laboratory to determine if the concentration of volatile organic compounds (VOCs) in the drum headspace is representative of the VOC concentration in the entire drum void space and to demonstrate that the VOC concentration in the void space of each layer of confinement can be estimated using a model incorporating diffusion and permeation transport principles and limited waste drum sampling data. An experimental test plan was developed requiring gas sampling of 66 transuranic (TRU) waste drums. This interim report summarizes the experimental measurements and model predictions of VOC concentration in the innermost layer of confinement from waste drums sampled and analyzed in FY 1994

  17. Concentrating photovoltaics for the Tropics. Final Report, June 1, 1978-February 28, 1979

    Energy Technology Data Exchange (ETDEWEB)

    1979-06-30

    The design and specification of a photovoltaic concentrator total energy system are presented. The design will provide nearly half the electrical energy needs and most of the thermal energy needs (absorption chillers) of the Center for Energy and Environment Research, University of Puerto Rico, and the hot water needs of the Oncologic Hospital and Children's Hospital, Puerto Rico Medical Center. The system will utilize 34,190 sq ft of 40X slat type concentrators with secondary CPC concentrators to provide 162 kWe. The combined photovoltaic/thermal collector system utilizes a 20,000 gal steel thermal storage tank, and two absorption refrigeration units which will produce a total of 149 tons of cooling. Detailed drawings and system fabrication and installation plans are included. Insolation data for the San Juan, Puerto Rico site are presented, and calculated system performance based on this data is presented. (WHK)

  18. Concentrating photovoltaics for the Tropics. Final Report, June 1, 1978-February 28, 1979

    Energy Technology Data Exchange (ETDEWEB)

    1979-06-30

    The design and specification of a photovoltaic concentrator total energy system are presented. The design will provide nearly half the electrical energy needs and most of the thermal energy needs (absorption chillers) of the Center for Energy and Environment Research, University of Puerto Rico, and the hot water needs of the Oncologic Hospital and Children's Hospital, Puerto Rico Medical Center. The system will utilize 34,190 sq ft of 40X slat type concentrators with secondary CPC concentrators to provide 162 kWe. The combined photovoltaic/thermal collector system utilizes a 20,000 gal steel thermal storage tank, and two absorption refrigeration units which will produce a total of 149 tons of cooling. Detailed drawings and system fabrication and installation plans are included. Insolation data for the San Juan, Puerto Rico site are presented, and calculated system performance based on this data is presented. (WHK)

  19. Racial differences in correlations between reported dietary intakes of carotenoids and their concentration biomarkers123

    Science.gov (United States)

    Arab, Lenore; Cambou, Mary C; Craft, Neal; Wesseling-Perry, Katherine; Jardack, Patricia; Ang, Alfonso

    2011-01-01

    Background: The predictive ability of dietary assessment methods to estimate specific circulating plasma carotenoid concentrations has been compared between African Americans and whites in only one study to date. Objective: The predictive abilities of 24-h dietary recalls and a food-frequency questionnaire in reporting dietary carotenoids when measured against concentration biomarkers were assessed in African Americans and compared with the findings in whites. Design: Data were collected from 250 generally healthy, nonsmoking white and African American participants aged 21–69 y, who completed 8 self-administered online 24-h dietary recalls and one National Cancer Institute diet-history questionnaire in the University of California Los Angeles (UCLA) Energetics Study. Mean intakes from 4-d dietary recalls were correlated with plasma xanthophyll concentrations (lutein + zeaxanthin and β-cryptoxanthin) and hydrocarbon carotenoids (lycopene, α-carotene, and β-carotene). Results: Adjusted correlations of plasma carotenoids with reported dietary intakes for African Americans in the 24-h dietary recall ranged from 0.03 for β-carotene to 0.40 for β-cryptoxanthin. For whites, the correlations ranged from 0.13 for lycopene to 0.51 for β-cryptoxanthin. Conclusions: Despite stronger validity in reported energy intakes for African Americans than for whites in the 24-h dietary recall in the Energetics Study, both recalls and food-frequency dietary assessment methods yielded lower correlations in African Americans than in whites. This finding might be attributable to reporting differences in both dietary sources and food preparation or to racially related genetic variants influencing circulating concentrations. The current findings support the need to account for differences in race, age, sex, and body mass index in regression calibrations of dietary reports and measurement error adjustments. PMID:21389177

  20. Airport Solar Photovoltaic Concentrator Project. Phase 1 - final report, June 1, 1978-February 28, 1979

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-01

    The system design, analysis, and specification, site preparation, and operation and evaluation plan for a 500 kWe photovoltaic power supply to be located at the Phoenix Sky Harbor International Airport in Phoenix, Arizona, are presented. The solar cell arrays are concentrator silicon solar cells with tracking 70X Cassegrain-type concentrators. The power conditioning system, tracking system, and control systems are described in detal. Environmental impact studies are described. Component specifications and drawings are included. (WHK)

  1. Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects

    DEFF Research Database (Denmark)

    Greenfield, Jerry R; Farooqi, I Sadaf; Keogh, Julia M

    2008-01-01

    objective was to determine whether glutamine increases circulating GLP-1 and GIP concentrations in vivo and, if so, whether this is associated with an increase in plasma insulin. DESIGN: We recruited 8 healthy normal-weight volunteers (LEAN), 8 obese individuals with type 2 diabetes or impaired glucose...... plasma insulin concentrations. Glutamine stimulated glucagon secretion in all 3 study groups. CONCLUSION: Glutamine effectively increases circulating GLP-1, GIP, and insulin concentrations in vivo and may represent a novel therapeutic approach to stimulating insulin secretion in obesity and type 2......BACKGROUND: Incretin hormones, such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), play an important role in meal-related insulin secretion. We previously demonstrated that glutamine is a potent stimulus of GLP-1 secretion in vitro. OBJECTIVE: Our...

  2. The Type 3 copper site is intact but labile in Type 2-depleted laccase

    DEFF Research Database (Denmark)

    Frank, P; Farver, O; Pecht, I

    1983-01-01

    We report results of experiments designed to characterize the Type 1 and Type 3 copper sites in Rhus laccase depleted of Type 2 copper (T2D). Use of the Lowry method for determining protein concentration yielded the value 5620 +/- 570 M-1 cm-1 for the extinction of the 615-nm absorption band...... as intensity perturbations at 280 and 615 nm. Comparison of difference spectra show that this 330-nm band derives from a Type 3 copper-bound peroxide and not from a reoxidized Type 3 site. Dioxygen reoxidation of ascorbate-reduced T2D laccase produced new difference bands at 330 nm (delta epsilon = 770 M-1 cm...

  3. Radon concentrations in different types of dwellings in Israel

    International Nuclear Information System (INIS)

    Epstein, L.; Koch, J.; Riemer, T.; Haquin, G.; Orion, I.

    2014-01-01

    The average radon concentration in Israeli dwellings was assessed by combining the results of a 2006 radon survey in single family houses with the results of a 2011 radon survey in apartments of multi-storey buildings. Both surveys were based on long-term measurements using CR-39 detectors. The survey in multi-storey buildings was intended to assess the influence of recent practices in the local building industry on the radon concentrations. These practices include the use of building materials with higher concentrations of the natural radionuclides in the last 20 y than before, as well as the improvement in sealing techniques over that period. Another practice in place since the early 1990's is the building of a shielded area in every apartment that is known as an RSS (residential secure space). The RSS is a room built from massive concrete walls, floor and ceiling that can be hermetically sealed and is intended to protect its residents from a missile attack. The influence of the above-mentioned features on radon concentrations was estimated by dividing the participating apartments into two groups: apartments in buildings >20 y, built using building materials with low concentrations of the natural radionuclides, regular sealing and without an RSS and apartments in buildings newer than 10 y, built using building materials with higher concentrations of the natural radionuclides, improved sealing and including an RSS. It was found that the average radon concentration in apartments in new buildings was significantly higher than in old buildings and the average radon concentration in single-family houses was significantly higher than in apartments in multi-storey buildings. Doses due to indoor radon were estimated on the basis of the updated information included in the 2009 International Commission on Radiological Protection statement on radon. (authors)

  4. Biaxial-Type Concentrated Solar Tracking System with a Fresnel Lens for Solar-Thermal Applications

    Directory of Open Access Journals (Sweden)

    Tsung Chieh Cheng

    2016-04-01

    Full Text Available In this paper, an electromechanical, biaxial-type concentrated solar tracking system was designed for solar-thermal applications. In our tracking system, the sunlight was concentrated by the microstructure of Fresnel lens to the heating head of the Stirling engine and two solar cells were installed to provide the power for tracking system operation. In order to obtain the maximum sun power, the tracking system traces the sun with the altitude-azimuth biaxial tracing method and accurately maintains the sun’s radiation perpendicular to the plane of the heating head. The results indicated that the position of heating head is an important factor for power collection. If the sunlight can be concentrated to completely cover the heating head with small heat loss, we can obtain the maximum temperature of the heating head of the Stirling engine. Therefore, the temperature of heating head can be higher than 1000 °C in our experiment on a sunny day. Moreover, the results also revealed that the temperature decrease of the heating head is less than the power decrease of solar irradiation because of the latent heat of copper and the small heat loss from the heating head.

  5. Stress Concentration and Its Mitigation Techniques in Flat Plate with Singularities - A Critical Review

    Directory of Open Access Journals (Sweden)

    Shubhashish Sanyal

    2012-01-01

    Full Text Available A number of analytical, numerical & experimental techniques are available for the reduction of stress concentration factor around discontinuities. Using various techniques the SCF around different discontinuities in a rectangular plate made up of different materials under different loading conditions have been reported in literature. Mitigation of stress concentration around different types of discontinuity is also reported in literature. This paper is to present an analysis and overview of emerging techniques developed for analysis as well as mitigation of stress concentration. The proposed methods in literature are compared.

  6. Ovarian Small Cell Carcinoma Hypercalcemic Type: A Case Report

    LENUS (Irish Health Repository)

    Rahma, M B.

    2016-09-01

    A 31-year-old female was diagnosed with small cell carcinoma of the ovary hypercalcaemic type (OSCCHT) post left oophorectomy. This is a rare aggressive ovarian tumour of which less than 300 cases were reported.

  7. Concentrating Solar Power. Report April 2009

    Energy Technology Data Exchange (ETDEWEB)

    Pihl, Erik (Chalmers Univ. of Technology, Enery and Environment, Goeteborg (Sweden))

    2009-04-15

    Concentrating solar power (CSP) technologies offer ways to utilise solar radiation by concentrating the light. In a concentrated form, the light can be utilised more cost efficiently. It is focused with mirrors or lenses and used either as a heat source in thermal power cycles (thermal CSP) or as a light source for high efficiency photovoltaic cells (concentrating photovoltaics, CPV). All concentrating systems use tracking to follow the movement of the sun, in two or three dimensions, and require direct sunlight (no diffusing clouds). CSP plants are often more complex, component wise than those based on flat PV. The extra cost of complexity is generally more than offset by the larger scales, the less need for expensive materials such as purified silicon and a better fit with the current energy infrastructure. Some thermal CSP plants offer great possibilities to deal with the intermittency of solar energy, as the heat generated can be stored in the form of a heated liquid in large tanks for many hours with little additional cost, and drive the thermal power generation also during cloudy periods or at night. CSP is growing rapidly and can be an important portion of future low-carbon energy systems. A prerequisite is that expected cost reductions are, at least largely, realised. In regions with good solar conditions (Mediterranean countries, US Southwest, Middle East, Australia etc), CSP systems already in the short-term future can satisfy significant shares of the power demand, to decrease CO{sub 2} emissions. Less solar-intensive regions (Northern Europe, much of North America etc) can be supplied with CSP power from solar-rich regions by using long distance power grids, for instance the high voltage DC cables being deployed and developed today

  8. Concentrated insulins: the new basal insulins

    Directory of Open Access Journals (Sweden)

    Lamos EM

    2016-03-01

    Full Text Available Elizabeth M Lamos,1 Lisa M Younk,2 Stephen N Davis3 1Division of Endocrinology, Diabetes and Nutrition, 2Department of Medicine, University of Maryland School of Medicine, 3Department of Medicine, University of Maryland Medical Center, Baltimore, MD, USA Introduction: Insulin therapy plays a critical role in the treatment of type 1 and type 2 diabetes mellitus. However, there is still a need to find basal insulins with 24-hour coverage and reduced risk of hypoglycemia. Additionally, with increasing obesity and insulin resistance, the ability to provide clinically necessary high doses of insulin at low volume is also needed. Areas covered: This review highlights the published reports of the pharmacokinetic (PK and glucodynamic properties of concentrated insulins: Humulin-R U500, insulin degludec U200, and insulin glargine U300, describes the clinical efficacy, risk of hypoglycemic, and metabolic changes observed, and finally, discusses observations about the complexity of introducing a new generation of concentrated insulins to the therapeutic market. Conclusion: Humulin-R U500 has a similar onset but longer duration of action compared with U100 regular insulin. Insulin glargine U300 has differential PK/pharmacodynamic effects when compared with insulin glargine U100. In noninferiority studies, glycemic control with degludec U200 and glargine U300 is similar to insulin glargine U100 and nocturnal hypoglycemia is reduced. Concentrated formulations appear to behave as separate molecular entities when compared with earlier U100 insulin analog compounds. In the review of available published data, newer concentrated basal insulins may offer an advantage in terms of reduced intraindividual variability as well as reducing the injection burden in individuals requiring high-dose and large volume insulin therapy. Understanding the PK and pharmacodynamic properties of this new generation of insulins is critical to safe dosing, dispensing, and administration

  9. Neocortical concentrations of neuropeptides in senile dementia of the Alzheimer and Lewy body type: comparison with Parkinson's disease and severity correlations.

    Science.gov (United States)

    Leake, A; Perry, E K; Perry, R H; Jabeen, S; Fairbairn, A F; McKeith, I G; Ferrier, I N

    1991-02-15

    Corticotropin releasing hormone (CRH), somatostatin (SRIF), and arginine vasopressin (AVP) concentrations were estimated using radioimmunoassay in the temporal and occipital cortices in postmortem brain from patients clinically and neuropathologically diagnosed as senile dementia of the Lewy body type (SDLT), senile dementia of the Alzheimer type (SDAT), and Parkinson's disease (PD) and from neurologically normal controls. The concentration of temporal and occipital neocortical CRH was diminished in both SDAT and SDLT compared to control values, whereas SRIF was reduced only in temporal cortex in both these conditions. In contrast, the concentrations of both CRH and SRIF were unaltered in PD. The concentrations of AVP in SDLT, SDAT, and PD were similar to those found in the control groups. The decrement in SRIF, but not CRH, was found to be correlated with some indices of severity of illness in SDAT; a similar but nonsignificant trend for SRIF was observed in SDLT.

  10. Some characteristics of heat production by stationary parabolic, cylindrical solar concentrator

    Energy Technology Data Exchange (ETDEWEB)

    Bojic, M.; Marjanovic, N.; Miletic, I.; Mitic, A. [Kragujevac Univ., Kragujevac (Serbia). Faculty of Mechanical Engineering; Stefanovic, V. [Nis Univ., Nis (Serbia). Faculty of Mechanical Engineering

    2009-07-01

    The use of solar energy for heating, cooling and electricity production was discussed with particular reference to the use of a stationary, asymmetric solar concentrator for conversion of solar energy to heat using a reflector and absorber. The infinite length CP-0A type stationary parabolic, cylindrical solar concentrator for heat production consists of the absorber (with water pipes) and parabolic, cylindrical reflector (with a metal surface). It has a geometrical concentration ratio of up to 4. This paper reported on a study that used the CATIA computer software to investigate how direct solar radiation approaches the concentrator aperture and the concentrator reflector. The propagation of light rays inside the concentrator to reach the absorber surface was examined. The study showed that the solar ray either hits the absorber directly or it bounces one or several time from the concentrator reflector. The efficiency of light rays was also calculated as a function of angles of incident of solar rays and type of reflector surface. 5 refs., 8 figs.

  11. Flow rate, pH and calcium concentration of saliva of children and adolescents with type 1 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    A.R. Moreira

    2009-08-01

    Full Text Available Alterations in salivary parameters may increase the caries risk in diabetic children, but, contradictory data on this issue have been reported. The aims of this study were to compare salivary parameters (flow rate, pH and calcium concentration between healthy and type 1 diabetes mellitus (T1DM individuals. The sample consisted of 7- to 18-year-old individuals divided into two groups: 30 subjects with T1DM (group A and 30 healthy control subjects (group B. Fasting glucose levels were determined. Unstimulated and stimulated saliva was collected. The pH of unstimulated saliva was measured with paper strips and an electrode. Calcium concentrations in stimulated saliva were determined with a selective electrode. Group A individuals had inadequate blood glucose control (HbA1C >9%, with means ± SD unstimulated salivary flow rate of 0.15 ± 0.1 mL/min compared to 0.36 ± 0.2 mL/min for group B (P < 0.01. Stimulated salivary flow rate was similar by both groups and above 2.0 mL/min. Saliva pH was 6.0 ± 0.8 for group A and significantly different from 7.0 ± 0.6 for group B (P < 0.01. Salivary calcium was 14.7 ± 8.1 mg/L for group A and significantly higher than 9.9 ± 6.4 mg/L for group B (P < 0.01. Except for elevated calcium concentrations in saliva, salivary parameters favoring caries such as low saliva pH and unstimulated salivary flow rate were observed in T1DM individuals.

  12. Dependence of the Mg-related acceptor ionization energy with the acceptor concentration in p-type GaN layers grown by molecular beam epitaxy

    International Nuclear Information System (INIS)

    Brochen, Stéphane; Brault, Julien; Chenot, Sébastien; Dussaigne, Amélie; Leroux, Mathieu; Damilano, Benjamin

    2013-01-01

    Hall effect and capacitance-voltage C(V) measurements were performed on p-type GaN:Mg layers grown on GaN templates by molecular beam epitaxy with a high range of Mg-doping concentrations. The free hole density and the effective dopant concentration N A −N D as a function of magnesium incorporation measured by secondary ion mass spectroscopy clearly reveal both a magnesium doping efficiency up to 90% and a strong dependence of the acceptor ionization energy Ea with the acceptor concentration N A . These experimental observations highlight an isolated acceptor binding energy of 245±25 meV compatible, at high acceptor concentration, with the achievement of p-type GaN:Mg layers with a hole concentration at room temperature close to 10 19 cm −3

  13. Final survey reports on radon concentration in Japan

    International Nuclear Information System (INIS)

    1997-03-01

    In order to grasp the present state of indoor radon concentration all over Japan, this survey was conducted in five years from Heisei 4 FY to 8 FY. Measurements were conducted using a radon and thoron separation apparatus so as to enable to develop radon and thoron separately. This was only one survey all over Japan obtained the only radon concentration by removing thoron perfectly. However, it was planned to obtain the mean indoor radon concentration all over Japan by limiting 20 houses for measurement aim because of limitation on numbers of the apparatus. In this survey, no extremely high region of the radon concentration was found. However, it was comparatively higher in Chugoku, Kinki and Kyushu-Okinawa areas, but was comparatively low in Kanto area. These results showed the same tendency as those of γ-ray level from the ground, and the radon concentration also showed temperature difference of a tendency of higher west and lower east. In this survey, seasonal variation of the radon concentration was found. In the third quarter (from October to December) maximum radon concentration (mean value: 15 Bq/cu m) and in the second quarter, the minimum concentration (mean value: 9 Bq/cu m) were observed, respectively. On comparing the indoor radon concentration of each housing structure used in enquete survey, concrete block house showed higher radon concentration. On its arithmetic mean, the radon concentration was high in order of concrete, steel frame, and wood constructions, and lowest in prefabricated house. The radon concentration of the concrete construction showed about 1.8 times higher than that of the wood construction. (G.K.)

  14. Low-Concentration Tributyltin Decreases GluR2 Expression via Nuclear Respiratory Factor-1 Inhibition

    OpenAIRE

    Ishida, Keishi; Aoki, Kaori; Takishita, Tomoko; Miyara, Masatsugu; Sakamoto, Shuichiro; Sanoh, Seigo; Kimura, Tomoki; Kanda, Yasunari; Ohta, Shigeru; Kotake, Yaichiro

    2017-01-01

    Tributyltin (TBT), which has been widely used as an antifouling agent in paints, is a common environmental pollutant. Although the toxicity of high-dose TBT has been extensively reported, the effects of low concentrations of TBT are relatively less well studied. We have previously reported that low-concentration TBT decreases ?-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptor subunit 2 (GluR2) expression in cortical neurons and enhances neuronal vulnerability ...

  15. Serum uric acid concentration is associated with early changes of glomerular filtration rate in patients with diabetes type 1 without increased albumin excretion.

    Science.gov (United States)

    Spaleniak, Sebastian; Korzeniewska-Dyl, Irmina; Moczulski, Dariusz

    2014-10-01

    The early loss of renal function in patients with type 1 diabetes may begin before proteinuria. Only 30% of patients with diabetes manifest overt proteinuria. According to the previous studies, increased urinary albumin excretion, which is considered a classic marker of progression of diabetic kidney disease, can regress to normal urine albumin excretion. The current studies conducted in patients with type 1 diabetes without increased urine albumin excretion showed that the uric acid concentration was an independent factor for the development of diabetic kidney disease. The aim of study was to assess the impact of uric acid concentration and to identify risk factors of the early glomerular filtration loss in patients with type 1 diabetes and normal urinary albumin excretion. 147 patients (61 women and 86 men) with type 1 diabetes without increased urine albumin excretion were analysed. GFR (gromerular filtration rate) was estimated based on the serum cystatin C concentration. Centile charts were used to determine the variation of uric acid concentration depending on GFR and gender. The mean value of the filtration rate for the study group was 117 ml/min/m2. The uric acid level above 90th percentile in relation to GFR was diagnosed in 8.2% of women and 0% of men, between 90th and 50th percentile in 44.3 % of women and 5.8% of men and below 50th percentile in 47.5% of women and 94.2% of men. Contrary to men in women higher serum acid concentration was strongly associated with higher glomerular filtration rate. Hyperfiltraion was diagnosed in 15 of women and 19 of men. The high normal uric acid concentration in women with type 1 diabetes might play a crucial role in development of hyperfiltration.

  16. The concentration and type of liquid smoke to suppress the development of Elsinoe fawcettii causing scab on citrus plant of Japansche citroen

    Directory of Open Access Journals (Sweden)

    Triwiratno A.

    2018-04-01

    Full Text Available Citrus is the main fruit commodity in Indonesia. Scab disease is a major disease in citrus plants. Scab disease control usually uses chemical fungicides that cause environmental pollution. Liquid smoke is a natural substance as a safer fungicide. The objective of this study was to analyze the ability of liquid smoke with the most effective concentration of three types of liquid smoke ie coconut shell, teak and falcata in suppressing the development of fungus Elsinoe fawcettii in citrus Japansche Citroen (JC. The identification and treatment carried out were analysis of phenol compounds contained in three types of liquid smoke (coconut shell, teak and falcata wood, testing of in vitro antifungal properties on growth of fungus E. fawcettii isolate in petri and in vivo sprouts against disease rate scab on JC citrus plant. The results showed that phenol content of coconut shell liquid smoke was 62.747 ml / L, 227.873 ml / L of teak wood and falcata wood was 115.587 ml / L. On observation of E. fawcettii fungal colony 14 days after inocculation (dai highest percentage inhibition was smoke falcata smoke 5% concentration, able to inhibit growth of E. fawcettii equal to 77,22% whereas the lowest concentration was coconut shell smoke concentration 2% with 10.14% inhibition rate. Observation of wet weight and dry weight of E. fawcetti result of falcata smoke smoke treatment of 5% and 1% concentration have the lowest wet weight and dry weight of 0.867 g and 0.030 g, while on observation of intensity and extent of disease attack in vivo treatment of liquid smoke shell coconut wood and falcata wood have almost the same level of effectiveness. The conclusions of this study indicate that three types of liquid smoke ie coconut shell, teak and falcata wood have the ability to suppress growth and development of E. fawcetti fungus both in vitro and in vivo, while the most effective type is falcata wood. The most effective concentration in suppressing growth and

  17. Effect of ethnicity, dietary intake and physical activity on plasma adiponectin concentrations among malaysian patients with type 2 diabetes mellitus.

    Science.gov (United States)

    Chin, Koo Hui; Sathyasurya, Daniel Robert; Abu Saad, Hazizi; Jan Mohamed, Hamid Jan B

    2013-01-01

    The Malaysian Health and morbidity Survey (2006) reported the highest prevalence of type 2 diabetes mellitus (T2DM) among the Indian population compared to the Malay and Chinese populations. Many studies have supported the important role of adiponectin in insulin-sensitizing, which is associated with T2DM. These studies have raised a research question whether the variation in prevalence is related to the adiponectin concentrations or the lifestyle factors. The purpose of this study is to determine whether the adiponectin concentrations differ between the Malay, Chinese and the Indian populations with T2DM. It is to investigate the association of adiponectin concentrations with ethnicity, dietary intake and physical activity too. In this cross-sectional study, a total of 210 T2DM patients with mean (SD) age of 56.73 (10.23) years were recruited from Penang, Malaysia. Data on demographic background, medical history, anthropometry (weight, height, visceral fat, percentage of body fat and waist circumference), dietary intake (3 days 24 hours diet recall) and physical activity (International Physical Activity Questionnaire) were obtained accordingly. Plasma adiponectin and routine laboratory tests (fasting blood sugar, HbA1c, total cholesterol, LDL, HDL and triglyceride) were performed according to standard procedure. After adjustment for physical activity and dietary intakes, the Indian population had significantly lower adiponectin concentrations (P = 0.003) when compared with the Malay and the Chinese populations, The Indian population also had significantly higher value of HbA1c (P = 0.017) and significantly lower HDL (P = 0.013). Plasma adiponectin concentrations was significantly associated with ethnicity (P = 0.011), dietary carbohydrate (P = 0.003) and physical activity total MET score (P = 0.026), after medical history, age, sex, total cholesterol and visceral fat adjusted. However, dietary carbohydrate and physical activity did not show significantly

  18. Effects of the multi-step activation process on the carrier concentration of p-type GaN

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae-Kwan [Department of Materials Science and Metallurgical Engineering, Sunchon National University, Sunchon, Chonnam 540-742 (Korea, Republic of); Jeon, Seong-Ran [LED Research and Business Division, Korea Photonics Technology Institute, Gwanju 500-779 (Korea, Republic of); Lee, Ji-Myon, E-mail: jimlee@sunchon.ac.kr [Department of Printed Electronics Engineering, Sunchon National University, Sunchon, Chonnam 540-742 (Korea, Republic of)

    2014-06-25

    Highlights: • Hole concentration of p-GaN was enhanced by multi-step activation process. • The O{sub 2} plasma treatment is attributed to the enhanced hole concentration of p-GaN. • PL peak intensity was also enhanced by MS activation process. - Abstract: A multi-step activation method, which include an oxygen plasma treatment, chemical treatment, and post annealing in N{sub 2} was proposed to enhance the hole concentration of a p-type GaN epitaxial layer. This process was found to effectively activate p-GaN by increasing the hole concentration compared to that of the conventionally annealed sample. After the optimal oxygen plasma treatment (10 min at a source and table power of 500 W and 100 W, respectively), followed by a HCl and buffered oxide etchant treatment, and then by a post-RTA process in a N{sub 2} environment, the hole concentration was increased from 4.0 × 10{sup 17} to 2.0 × 10{sup 18} cm{sup −3}. The oxygen plasma was found to effectively remove the remaining H atoms and subsequent wet treatment can effectively remove the GaO{sub x} that had formed during O plasma treatment, resulting in the higher intensity of photoluminescence.

  19. Monitoring of radon concentration in dwellings

    International Nuclear Information System (INIS)

    Kurosawa, Ryuhei

    1991-01-01

    Radon problems in dwellings have recently received much attention. Radon concentration in dwellings, as well as in the general environment, varies with various factors such as meteorological conditions and soil components. Therefore, a long term monitoring of radon concentration is required to obtain an average concentration. This paper reviews a passive type radon monitor that is handy and allows a long term radon monitoring. It provides the structure and principle of the radon monitor, covering the type, filter function, sensitivity of diffusion collecting type (cup type), electrostatic collecting type, adsorption collecting type, and detector of radon monitor. Actual examples of the radon monitor are also given. Radon daughter nuclides will have become major foci of exposure countermeasures. In the future, the development of a passive type monitor for determining potential alpha energy concentration is required. (N.K.)

  20. Cannabis species and cannabinoid concentration preference among sleep-disturbed medicinal cannabis users.

    Science.gov (United States)

    Belendiuk, Katherine A; Babson, Kimberly A; Vandrey, Ryan; Bonn-Miller, Marcel O

    2015-11-01

    Individuals report using cannabis for the promotion of sleep, and the effects of cannabis on sleep may vary by cannabis species. Little research has documented preferences for particular cannabis types or cannabinoid concentrations as a function of use for sleep disturbances. 163 adults purchasing medical cannabis for a physical or mental health condition at a cannabis dispensary were recruited. They provided self-report of (a) whether cannabis use was intended to help with sleep problems (e.g. insomnia, nightmares), (b) sleep quality (PSQI), (c) cannabis use (including preferred type), and (d) symptoms of DSM-5 cannabis dependence. 81 participants reported using cannabis for the management of insomnia and 14 participants reported using cannabis to reduce nightmares. Individuals using cannabis to manage nightmares preferred sativa to indica strains (Fisher's exact test (2) = 6.83, p < 0.05), and sativa users were less likely to endorse DSM-5 cannabis dependence compared with those who preferred indica strains (χ(2)(2) = 4.09, p < 0.05). Individuals with current insomnia (t(9) = 3.30, p < 0.01) and greater sleep latency (F(3,6) = 46.7, p < 0.001) were more likely to report using strains of cannabis with significantly higher concentrations of CBD. Individuals who reported at least weekly use of hypnotic medications used cannabis with lower THC concentrations compared to those who used sleep medications less frequently than weekly (t(17) = 2.40, p < 0.05). Associations between sleep characteristics and the type of cannabis used were observed in this convenience sample of individuals using cannabis for the management of sleep disturbances. Controlled prospective studies are needed to better characterize the impact that specific components of cannabis have on sleep. Copyright © 2015. Published by Elsevier Ltd.

  1. Type of corn and grinding degree in a concentrate supplied to suckling calves

    Directory of Open Access Journals (Sweden)

    Cibele Santos Ferreira

    2012-06-01

    Full Text Available The objective was to assess the effects of a concentrate consisting of two types of corn: flint and dent, with three different grinding degrees (1, 3 and 5 mm, as a function of intake, performance and digestibility of three crossbred dairy suckling heifers. A randomized block design involving 54 crossbred heifers in a 2 × 3 factorial arrangement was used to assess intake and performance patterns. In order to assess digestibility, the experimental design was completely randomized, consisting of 24 crossbred heifers. Weighting and measurements of height at withers and thoracic perimeter were performed. There was no significant interaction between grinding degree and corn type for any of the studied variables. The daily intake of concentrate dry matter was higher for flint corn (243 g/day as compared with dent corn (160 g/day. The grinding degree caused difference in the dry matter, crude protein and ether extract intake, with higher intake when 3 and 5 mm sieves were used in the process. There was no difference regarding average daily gain and increased withers, croup and thoracic perimeter. Likewise, feed conversion did not differ. Regarding dry matter digestibility, there was an effect resulting from the hardness of corn (78.9% for dent, and 84.3% and for flint corn. As for the grinding degree, the highest value of dry matter digestibility was found when using 5 mm sieves (84.2%, whereas the percentage values found for 1 mm and 3 mm mesh sieves were 79.1% and 78.1%, respectively. It is recommended that heifer calves in the early stage of growth be fed flint corn ground through 3 or 5 mm mesh sieves.

  2. The Performance of CO2 Laser Photoacoustic Spectrometer In Concentration Acetone Detection As Biomarker For Diabetes Mellitus Type 2

    Science.gov (United States)

    Tyas, F. H.; Nikita, J. G.; Apriyanto, D. K.; Mitrayana; Amin, M. N.

    2018-04-01

    Breath analysis is useful for the diagnosis of human diseases and monitoring of metabolic status. However, because of the low concentrations and the large numbers of compounds in the breath, the breath analysis requires highly sensitive and highly selective instruments to identify and determine the concentrations of certain biomarkers [1]. Various methods developed over the past 20 years to detect biomarker gases [2]. CO2 laser photoacoustic spectroscopy offers a sensitive technique for the detection and monitoring of gas footprints at low concentrations [3]. The performance of photoacoustic spectrometer (PAS) examined with intracavity configuration. In this research, the highest observed intracavity power was (49,96 ± 0,02) W for active medium gas composition He: N2: CO2 at 30:50:50. The highest laser absorption line for standard acetone gas set at 10P20, and the lowest detection limit set at (30 ± 4) ppb. For application purposes, the photoacoustic spectrometer was used to measure the concentration of acetone gas in exhaled gases from a group of patients with type 2 diabetes mellitus and a group of healthy volunteers. Exhaled gas sampling method took manually, and the measurement result was examined using multicomponent analysis. The measurement showed that the highest acetone gas concentration for type 2 diabetes mellitus patients was (162 ± 3) × 10 ppb and the lowest one was (101 ± 3) × 10 ppb. Furthermore, for healthy volunteers, the highest acetone gas concentration was (85 ± 3) × 10 ppb and the lowest one was (15 ± 3) × 10 ppb.

  3. Experimental analysis of an effect of the nutrient type and its concentration on the rheological properties of the baker’s yeast suspensions

    Directory of Open Access Journals (Sweden)

    Major-Godlewska Marta

    2015-09-01

    Full Text Available The aim of the study presented was to experimentally analyze an effect of the nutrient type and its concentration on the variability of rheological properties of the baker’s yeast suspensions for different time periods. Aqueous suspensions of the baker’s yeast of various concentration (solution I, without nutrient and yeasts suspended in aqueous solution of sucrose or honey as nutrients with different concentration (solution II or solution III were tested. Experiments were carried out using rotational rheoviscometer of type RT10 by a company HAAKE. The measurements were conducted for different time periods (from 1 h up to 144 h at given fluid temperature. On the basis of the obtained data, rheological characteristics of the aqueous solution of baker’s yeast suspensions without and with nutrients of different sucrose or honey concentration were identified and mathematically described.

  4. [Cognitive behavioral therapy for tension-type headache: a case report].

    Science.gov (United States)

    Salman, İsmail Barış; Sertel Berk, Hanife Özlem

    2017-10-01

    Tension-type headache has a very high socioeconomic impact, and its lifetime prevalence is reported to be between 30% and 78% in different studies. It is widely acknowledged that noninvasive management with a multidisciplinary approach should be considered for the treatment of tension-type headache. Cognitive behavioral therapy and relaxation exercises are efficient techniques. This article illustrates the application of a cognitive behavioral therapy protocol enhanced with progressive muscle stretching and relaxation exercises in the treatment of chronic tension-type headache via a case report. Our patient had an ongoing headache for 6 years when he was referred to us by the department of psychiatry. After 10 cognitive behavioral therapy sessions, the patient had learned to notice muscle tension and relax the muscles as well as to recognize and express his emotions in a better way. He became aware of automatic thoughts and learned to find alternative thoughts. Headache severity decreased, and he was able to increase participation in daily life activities.

  5. Effects of inoculum type and bulk dissolved oxygen concentration on achieving partial nitrification by entrapped-cell-based reactors.

    Science.gov (United States)

    Rongsayamanont, Chaiwat; Limpiyakorn, Tawan; Khan, Eakalak

    2014-07-01

    An entrapment of nitrifiers into gel matrix is employed as a tool to fulfill partial nitrification under non-limiting dissolved oxygen (DO) concentrations in bulk solutions. This study aims to clarify which of these two attributes, inoculum type and DO concentration in bulk solutions, is the decisive factor for partial nitrification in an entrapped-cell based system. Four polyvinyl alcohol entrapped inocula were prepared to have different proportions of nitrite-oxidizing bacteria (NOB) and nitrite-oxidizing activity. At a DO concentration of 3 mg l(-1), the number of active NOB cells in an inoculum was the decisive factor for partial nitrification enhancement. However, when the DO concentration was reduced to 2 mg l(-1), all entrapped cell inocula showed similar degrees of partial nitrification. The results suggested that with the lower bulk DO concentration, the preparation of entrapped cell inocula is not useful as the DO level becomes the decisive factor for achieving partial nitrification. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Radiologic reports : attitudes, preferred type, and opinion of referring physicians

    International Nuclear Information System (INIS)

    Kim, Won Young; Hwang, Seong Su; Ahn, Myeong Im and others

    2001-01-01

    To determine referring physicians' general attitudes, preferred reporting types, and opinions on radiologic reports. A survey questionnaire was distributed to the 315 staff and residents of four university hospitals with 400 to 800 beds, and a total of 228 physicians responded. The questionnaire aimed to determine of the general attitude of referring physicians to radiologic reports, the type of report they preferred, and other opinions and suggestions. The responses elicited, as well as discrepancies among residents, staff, internist, and surgeons, were analyzed. Most referring physicians replied that they read an entire report regardless of its length, and the second majority read the conclusion first and then the remainder of the report only if clarification was required. With regard to report length, physicians answered that reports describing the findings of conventional radiography were often too short, while those dealing with MRI were verbose. The majority experienced occasional confusion when reading a report, the major cause being grammatical errors and incomprehensible sentence structure. When confused, most physicians consulted the radiologist ; staff showed a greater inclination than residents to pursue this option. Most physicians preferred brief phrases or telegraphic-style sentences to a style which stressed completeness and detail, a preference which was statistically higher among residents than staff. Whereas physicians favored a brief radiologic report in cases of normal radiologic findings, conventional radiologic studies or no clinical findings, they wished to see a more detailed report in cases of abnormal radiologic findings, specific radiologic studies (special radiographs, US, CT, or MRI), or positive clinical findings. This need for more detail was expressed more frequently by internists than by surgeons. If implemented, the results of this study can be expected to enhance the quality and comprehensibility of radiologic reports, and may

  7. Cystic fibrosis with normal sweat chloride concentration: case report

    Directory of Open Access Journals (Sweden)

    Silva Filho Luiz Vicente Ferreira da

    2003-01-01

    Full Text Available Cystic fibrosis is a genetic disease usually diagnosed by abnormal sweat testing. We report a case of an 18-year-old female with bronchiectasis, chronic P. aeruginosa infection, and normal sweat chloride concentrations who experienced rapid decrease of lung function and clinical deterioration despite treatment. Given the high suspicion ofcystic fibrosis, broad genotyping testing was performed, showing a compound heterozygous with deltaF508 and 3849+10kb C->T mutations, therefore confirming cystic fibrosis diagnosis. Although the sweat chloride test remains the gold standard for the diagnosis of cystic fibrosis, alternative diagnostic tests such as genotyping and electrophysiologic measurements must be performed if there is suspicion of cystic fibrosis, despite normal or borderline sweat chloride levels.

  8. Effect of Plasticizer Type and Concentration on Tensile, Thermal and Barrier Properties of Biodegradable Films Based on Sugar Palm (Arenga pinnata Starch

    Directory of Open Access Journals (Sweden)

    Muhammed L. Sanyang

    2015-06-01

    Full Text Available The use of starch based films as a potential alternative choice to petroleum derived plastics is imperative for environmental waste management. This study presents a new biopolymer (sugar palm starch for the preparation of biodegradable packaging films using a solution casting technique. The effect of different plasticizer types (glycerol (G, sorbitol (S and glycerol-sorbitol (GS combination with varying concentrations (0, 15, 30 and 45, w/w% on the tensile, thermal and barrier properties of sugar palm starch (SPS films was evaluated. Regardless of plasticizer types, the tensile strength of plasticized SPS films decreased, whereas their elongation at break (E% increased as the plasticizer concentrations were raised. However, the E% for G and GS-plasticized films significantly decreased at a higher plasticizer concentration (45% w/w due to the anti-plasticization effect of plasticizers. Change in plasticizer concentration showed an insignificant effect on the thermal properties of S-plasticized films. The glass transition temperature of SPS films slightly decreased as the plasticizer concentration increased from 15% to 45%. The plasticized films exhibited increased water vapor permeability values from 4.855 × 10−10 to 8.70 × 10−10 g·m−1·s−1·Pa−1, irrespective of plasticizer types. Overall, the current study manifested that plasticized sugar palm starch can be regarded as a promising biopolymer for biodegradable films.

  9. "Type Ia Supernovae: Tools for Studying Dark Energy" Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Woosley, Stan [Lick Observatory, San Jose, CA (United States); Kasen, Dan [Univ. of California, Berkeley, CA (United States)

    2017-05-10

    Final technical report for project "Type Ia Supernovae: Tools for the Study of Dark Energy" awarded jointly to scientists at the University of California, Santa Cruz and Berkeley, for computer modeling, theory and data analysis relevant to the use of Type Ia supernovae as standard candles for cosmology.

  10. Multiple solid pilocytic astrocytomas in cerebleiium with neurofibromatosis type: A case report

    International Nuclear Information System (INIS)

    Choi, Seo Young; Kim, Myung Soon; Kim, Young Ju

    2014-01-01

    Pilocytic astrocytoma usually has a classic imaging manifestation of a solitary, cyst-like mass with a strong contrast-enhancing mural nodule. There is only one published report so far of multiple solid and cyst type pilocytic astrocytomas in the cerebellum in neurofibromatosis type 1 (NF1) patient from the United States in 2007. We report a case of pilocytic astrocytoma presenting with only solid, multiple pilocytic astrocytomas in the cerebellum in NF1 patient.

  11. Flow rate, pH and calcium concentration of saliva of children and adolescents with type 1 diabetes mellitus.

    Science.gov (United States)

    Moreira, A R; Passos, I A; Sampaio, F C; Soares, M S M; Oliveira, R J

    2009-08-01

    Alterations in salivary parameters may increase the caries risk in diabetic children, but, contradictory data on this issue have been reported. The aims of this study were to compare salivary parameters (flow rate, pH and calcium concentration) between healthy and type 1 diabetes mellitus (T1DM) individuals. The sample consisted of 7- to 18-year-old individuals divided into two groups: 30 subjects with T1DM (group A) and 30 healthy control subjects (group B). Fasting glucose levels were determined. Unstimulated and stimulated saliva was collected. The pH of unstimulated saliva was measured with paper strips and an electrode. Calcium concentrations in stimulated saliva were determined with a selective electrode. Group A individuals had inadequate blood glucose control (HbA(1C) >9%), with means +/- SD unstimulated salivary flow rate of 0.15 +/- 0.1 mL/min compared to 0.36 +/- 0.2 mL/min for group B (P salivary flow rate was similar by both groups and above 2.0 mL/min. Saliva pH was 6.0 +/- 0.8 for group A and significantly different from 7.0 +/- 0.6 for group B (P Salivary calcium was 14.7 +/- 8.1 mg/L for group A and significantly higher than 9.9 +/- 6.4 mg/L for group B (P salivary parameters favoring caries such as low saliva pH and unstimulated salivary flow rate were observed in T1DM individuals.

  12. Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    N. Priyanka

    2013-01-01

    Full Text Available Introduction. This study was designed to correlate the serum and gingival crevicular fluid (GCF levels of progranulin (PGRN and high sensitivity C-reactive protein (hs CRP in chronic periodontitis and type 2 diabetes mellitus (DM. Design. PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodontitis, and type 2 DM with chronic periodontitis. Results. The mean PGRN and hs CRP concentrations in serum and GCF were the highest for group 3 followed by group 2 and the least in group 1. Conclusion. PGRN and hs CRP may be biomarkers of the inflammatory response in type 2 DM and chronic periodontitis.

  13. Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes

    Science.gov (United States)

    Priyanka, N.; Kumari, Minal; Kalra, Nitish; Arjun, P.; Naik, Savitha B.; Pradeep, A. R.

    2013-01-01

    Introduction. This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM). Design. PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodontitis, and type 2 DM with chronic periodontitis. Results. The mean PGRN and hs CRP concentrations in serum and GCF were the highest for group 3 followed by group 2 and the least in group 1. Conclusion. PGRN and hs CRP may be biomarkers of the inflammatory response in type 2 DM and chronic periodontitis. PMID:24191130

  14. Plasma Concentrations of Perfluoroalkyl Substances and Risk of Type 2 Diabetes

    DEFF Research Database (Denmark)

    Sun, Qi; Zong, Geng; Valvi, Damaskini

    2018-01-01

    between PFAS exposures and subsequent incidence of T2D in the Nurses' Health Study II (NHSII). In addition, we aimed to evaluate potential demographic and lifestyle determinants of plasma PFAS concentrations. METHODS: A prospective nested case-control study of T2D was conducted among participants who were......BACKGROUND: Emerging evidence suggests that perfluoroalkyl substances (PFASs) are endocrine disruptors and may contribute to the etiology of type 2 diabetes (T2D), but this hypothesis needs to be clarified in prospective human studies. OBJECTIVES: Our objective was to examine the associations...... free of diabetes, cardiovascular disease, and cancer in 1995-2000 [(mean±SD): 45.3±4.4y) of age]. We identified and ascertained 793 incident T2D cases through 2011 (mean±SD) years of follow-up: 6.7±3.7y). Each case was individually matched to a control (on age, month and fasting status at sample...

  15. Effects of vehicle ventilation system, fuel type, and in-cabin smoking on the concentration of toluene and ethylbenzene in Pride cars

    Directory of Open Access Journals (Sweden)

    Masoud Rismanchian

    2013-01-01

    Conclusion: The ventilation condition, fuel type, and in-cabin smoking were not significantly impressive on the toluene and ethylbenzene concentrations inside the cars. However, simultaneous usage of the vehicle ventilation system and natural ventilation (windows could lead to little decrease in toluene concentration levels inside the car, while smoking consumption by passengers can increase them.

  16. Low serum magnesium concentrations are associated with a high prevalence of premature ventricular complexes in obese adults with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Del Gobbo Liana C

    2012-03-01

    Full Text Available Abstract Background Premature ventricular complexes (PVC predict cardiovascular mortality among several adult populations. Increased arrhythmia prevalence has been reported during controlled magnesium (Mg depletion studies in adults. We thus hypothesized that serum magnesium (sMg concentrations are inversely associated with the prevalence of PVC in adults at high cardiovascular risk. Methods Anthropometric, demographic and lifestyle characteristics were assessed in 750 Cree adults, aged > 18 yrs, who participated in an age-stratified, cross-sectional health survey in Quebec, Canada. Holter electrocardiograms recorded heart rate variability and cardiac arrhythmias for two consecutive hours. Multivariate logistic regression was used to evaluate the associations between sMg and PVC. Results PVC prevalence in adults with hypomagnesemia (sMg ≤ 0.70 mmol/L was more than twice that of adults without hypomagnesemia (50% vs. 21%, p = 0.015; results were similar when adults with cardiovascular disease history were excluded. All hypomagnesemic adults with PVC had type 2 diabetes (T2DM. Prevalence of PVC declined across the sMg concentration gradient in adults with T2DM only (p 0.70 mmol/L was 0.24 (95% CI: 0.06-0.98 p = 0.046 compared to those with sMg ≤ 0.70 mmol/L. Conclusions sMg concentrations were inversely associated with the prevalence of PVC in patients with T2DM in a dose response manner, indicating that suboptimal sMg may be a contributor to arrhythmias among patients with T2DM.

  17. Palaeolithic diet decreases fasting plasma leptin concentrations more than a diabetes diet in patients with type 2 diabetes

    DEFF Research Database (Denmark)

    Fontes-Villalba, Maelán; Lindeberg, Staffan; Granfeldt, Yvonne

    2016-01-01

    Background: We have previously shown that a Palaeolithic diet consisting of the typical food groups that our ancestors ate during the Palaeolithic era, improves cardiovascular disease risk factors and glucose control compared to the currently recommended diabetes diet in patients with type 2...... diabetes. To elucidate the mechanisms behind these effects, we evaluated fasting plasma concentrations of glucagon, insulin, incretins, ghrelin, C-peptide and adipokines from the same study. Methods: In a randomised, open-label, cross-over study, 13 patients with type 2 diabetes were randomly assigned...

  18. Hydrodynamic problems of heavy liquid metal coolants technology in loop-type and mono-block-type reactor installations

    International Nuclear Information System (INIS)

    Orlov, Yuri I.; Efanov, Alexander D.; Martynov, Pyotr N.; Gulevsky, Valery A.; Papovyants, Albert K.; Levchenko, Yuri D.; Ulyanov, Vladimir V.

    2007-01-01

    In the report, the influence of hydrodynamics of the loop with heavy liquid metal coolants (Pb and Pb-Bi) on the realization methods and efficiency of the coolant technology for the reactor installations of loop, improved loop and mono-block type of design has been studied. The last two types of installations, as a rule, are characterized by the following features: availability of loop sections with low hydraulic head and low coolant velocities, large squares of coolant free surfaces; absence of stop and regulating valve, auxiliary pumps on the coolant pumping-over lines. Because of the different hydrodynamic conditions in the installation types, the tasks of the coolant technology have specific solutions. The description of the following procedures of coolant technology is given in the report: purification by hydrogen (purification using gas mixture containing hydrogen), regulation of dissolved oxygen concentration in coolant, coolant filtrating, control of dissolved oxygen concentration in coolant. It is shown that change of the loop design made with economic purpose and for improvement of the installation safety cause additional requirements to the procedures and apparatuses of the coolant technology realization

  19. Correlation between lamivudine plasma concentrations and patient self-reported adherence to antiretroviral treatment in experienced HIV patients

    Directory of Open Access Journals (Sweden)

    Minzi OM

    2011-11-01

    Full Text Available OM Minzi1, V Mugoyela2, LL Gustafsson31Unit of Pharmacology and Therapeutics, 2Department of Medicinal Chemistry, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania; 3Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, SwedenBackground: Adherence to antiretroviral treatment (ART is important to achieve treatment success in human immunodeficiency virus (HIV-infected patients. Most HIV clinics apply the patient self-report (PSR method. However, the reliability of this method in experienced HIV patients remains questionable.Purpose: To validate the PSR method for measuring adherence to ART using lamivudine (3TC plasma concentrations in experienced HIV patients.Methods: The study was conducted in Dar Es Salaam and involved 220 patients who were receiving ART services at HIV clinics for more than 12 months. Self-reported adherence information to ART was obtained on the day of HIV clinic visit. The patients were asked to mention the number of doses missed within the past 7 days. In addition, blood samples (2 mL were collected from each patient on the same day. The blood samples were determined for 3TC plasma concentrations. The target 3TC plasma concentration as indicator concentration for adherent patients was determined in 20 patients who took their evening dose of antiretrovirals under supervision. The blood from these patients was drawn 3 hours after drug administration.Results: Complete drug levels of 3TC and self-reported adherence data was obtained in 200 treatment-experienced HIV patients. Lamivudine plasma concentrations obtained in these patients ranged between 0.02–17.36 µg/mL. The mean time from dose administration to blood drawing was 3.1 ± 1.2 hours with coefficient of variation >39%. The mean 3TC plasma concentration obtained in 20 patients who took their antiretroviral dose under supervision was

  20. High hole mobility p-type GaN with low residual hydrogen concentration prepared by pulsed sputtering

    Science.gov (United States)

    Arakawa, Yasuaki; Ueno, Kohei; Kobayashi, Atsushi; Ohta, Jitsuo; Fujioka, Hiroshi

    2016-08-01

    We have grown Mg-doped GaN films with low residual hydrogen concentration using a low-temperature pulsed sputtering deposition (PSD) process. The growth system is inherently hydrogen-free, allowing us to obtain high-purity Mg-doped GaN films with residual hydrogen concentrations below 5 × 1016 cm-3, which is the detection limit of secondary ion mass spectroscopy. In the Mg profile, no memory effect or serious dopant diffusion was detected. The as-deposited Mg-doped GaN films showed clear p-type conductivity at room temperature (RT) without thermal activation. The GaN film doped with a low concentration of Mg (7.9 × 1017 cm-3) deposited by PSD showed hole mobilities of 34 and 62 cm2 V-1 s-1 at RT and 175 K, respectively, which are as high as those of films grown by a state-of-the-art metal-organic chemical vapor deposition apparatus. These results indicate that PSD is a powerful tool for the fabrication of GaN-based vertical power devices.

  1. Reconstruction of national distribution of indoor radon concentration in Russia using results of regional indoor radon measurement programs

    International Nuclear Information System (INIS)

    Yarmoshenko, I.; Malinovsky, G.; Vasilyev, A.; Zhukovsky, M.

    2015-01-01

    The aim of the paper is a reconstruction of the national distribution and estimation of the arithmetic average indoor radon concentration in Russia using the data of official annual 4-DOZ reports. Annual 4-DOZ reports summarize results of radiation measurements in 83 regions of Russian Federation. Information on more than 400 000 indoor radon measurements includes the average indoor radon isotopes equilibrium equivalent concentration (EEC) and number of measurements by regions and by three main types of houses: wooden, one-storey non-wooden, and multi-storey non-wooden houses. To reconstruct the national distribution, all-Russian model sample was generated by integration of sub-samples created using the results of each annual regional program of indoor radon measurements in each type of buildings. According to indoor radon concentration distribution reconstruction, all-Russian average indoor radon concentration is 48 Bq/m"3. Average indoor radon concentration by region ranges from 12 to 207 Bq/m"3. The 95-th percentile of the distribution is reached at indoor radon concentration 160 Bq/m"3. - Highlights: • Reconstruction of indoor radon concentration distribution in Russia was carried out. • Data of official annual 4-DOZ reports were used. • All-Russian average indoor radon concentration is 48 Bq/m"3. • The 95-th percentile is 160 Bq/m"3.

  2. Prostatic-type polyp in the bladder. A case report

    DEFF Research Database (Denmark)

    Hansen, B J; Christensen, S W; Eldrup, J

    1989-01-01

    A case of prostatic-type polyp in the wall of the urinary bladder in a 73-year-old male is presented. The literature concerning ectopic prostatic tissue in the urinary tract is reviewed and it is concluded that the lesion is benign. However, recurrence has been reported in two cases. The etiology...

  3. Analysis of Pb, Cd, Cr and Ni concentrations in types of cabbage marketed in Hamedan City

    Directory of Open Access Journals (Sweden)

    S Sobhanardakani

    2015-02-01

    Full Text Available Today, due to the accumulation of heavy metals in vegetables irrigated with wastewater and treated with sewage sludge has become increasing concern in the field of food safety and health of consumers. Therefore this study was conducted for analysis of Pb, Cd, Cr and Ni concentrations of 3 types of cabbage marketed in Hamedan City during 2013. For this purpose after buying 30 samples of each species of cabbage and then acid digestion of the samples according to standard methods, elements (Pb, Cd, Cr and Ni were determined using ICP-OES (Varian, 710-ES, Australia. All statistical analyses were performed using the SPSS statistical package. The results showed that mean concentrations of Pb, Cd, Cr and Ni in Cabbage samples were 15.53±3.43, 59.33±5.35, 2.22±1.61 and 14.97±2.83 mg/kg, respectively; mean concentrations of these elements in red cabbage samples were 23.03±5.89, 37.53±4.21, 13.33±3.24 and 15.03±3.04 mg/kg, respectively; and mean concentrations of elements in broccoli samples were 8.00±3.63, 45.90±5.86, 8.20±3.39 and 16.93±3.08 mg/kg, respectively. Also comparison of the mean concentrations of evaluated metals in specimens with FAO/WHO permissible limits showed that significant difference (p

  4. Results of long-term measurement of 222Rn concentrations in outdoor atmosphere

    International Nuclear Information System (INIS)

    Holy, K.; Boehm, R.; Polaskova, A.; Hola, O.

    1998-01-01

    Results are reported of the authors' long-term measurement of 222 Rn concentrations in the outdoor atmosphere. The measurements started in 1987 and were performed at a height of 1.5 m over a grass-covered ground surface, using till 1991 a Lucas type scintillation chamber and later a large volume scintillation chamber. Graphs are presented and discussed of the course of average monthly radon concentration in 1987-1996 and of annual courses of radon concentration for different time intervals of the day over 1991 to 1995. (A.K.)

  5. Spinocerebellar ataxia type 7: Report of an Indian family

    Directory of Open Access Journals (Sweden)

    Gurusidheshwar M Wali

    2013-01-01

    Full Text Available Spinocerebellar ataxia type 7 (SCA7 is a form of autosomal dominant cerebellar ataxia which is associated with pigmentary retinal degeneration. It is known for its world-wide rarity except in the Scandinavian countries. It is very rarely reported from India and the neighbouring Asian countries . The present report describes the neurogenetic findings of a family of SCA7, from the northern part of Karnataka in South India. It documents the wide intrafamilial phenotypic variability, which could be correlated with the CAG repeat counts and phenomenon of anticipation. Genotype phenotype correlation highlighted certain disparities in comparison with the previous studies. The report highlights the need for multiethnic population studies and the role of genetic counseling and prenatal testing in SCA7 patients.

  6. A Mammary Type Myofibroblastoma in the Pelvic Cavity: A Case Report

    International Nuclear Information System (INIS)

    Park, Seong Hoon; Lee, Il Gi; Kim, Seong Hoon; Shin, Ji Yeol

    2009-01-01

    Mammary-type myofibroblastoma is very rare, benign mesenchymal neoplasm that's composed of spindleshaped cells with features of myofibroblasts, and these cells are embedded in a stroma with hyalinization. The most common location of the tumor is the inguinal area and to the best of our our knowledge, there has been no such case that this type of tumor has presented as a pelvic space mass. We report here on a very rare form of mammary-type myofibroblastoma and we include the ultrasound and CT images

  7. Maximum Permissible Concentrations and Negligible Concentrations for pesticides

    NARCIS (Netherlands)

    Crommentuijn T; Kalf DF; Polder MD; Posthumus R; Plassche EJ van de; CSR

    1997-01-01

    Maximum Permissible Concentrations (MPCs) and Negligible Concentrations (NCs) derived for a series of pesticides are presented in this report. These MPCs and NCs are used by the Ministry of Housing, Spatial Planning and the Environment (VROM) to set Environmental Quality Objectives. For some of the

  8. The concentration of natural radionuclides in various types of building materials in Slovakia

    Energy Technology Data Exchange (ETDEWEB)

    Cabanekova, H [Inst. of Peventive and Clinical Medicine, Bratislava (Slovakia)

    1996-12-31

    The concentration of the natural radionuclides in various types of building materials was determined by the gamma spectrometry analysis using 130 cm{sup 3} high purity germanium detector and MCA LIVIUS 2000. Radium-226 and thorium-232 was assessed through their progeny photo peaks. The specific activity of both nuclides as weighted average of their photo peaks was determined. Potassium-40 was measured directly via its 1460 keV peak. The radium equivalent activity was calculate from specific activities of radium-226, thorium-232 and potassium-40. All samples were measured in 4{sup p}i{sup g}eometry. The building materials and products were milled and screened with 2-3 mm sieve. After drying the samples were stored in 450 cm{sup 3} sealed polyethylene container for 30 days ingrowing period. The results of analysis are corrected to the background distribution and to the self absorption in the volume of the samples. The efficiency calibration is realized using the reference sources distributed by IAEA in Vienna and by the Institute for Radionuclide Production in Prague The measured activity concentrations of the buildings materials are given. There are shown the minimum and maximum values for different investigated materials. (J.K.) 4 tabs., 5 refs.

  9. Major, Trace Element Concentration and Triple-Oxygen Isotope Compositions of G- and I-Type Spherules from the Sør Rondane Mountains, East Antarctica

    Science.gov (United States)

    Soens, B.; Goderis, S.; Greenwood, R. C.; McKibbin, S.; Van Ginneken, M.; Vanhaecke, F.; Debaille, V.; Franchi, I. A.; Claeys, Ph.

    2017-07-01

    We present new major, trace element concentration (LA-ICP-MS) and triple-oxygen isotope (LF-IRMS) data for G- and I-type cosmic spherules. This study suggests that both types of micrometeorites may originate from ordinary chondrite parent bodies.

  10. Statistical relationship between surface PM10 concentration and aerosol optical depth over the Sahel as a function of weather type, using neural network methodology

    Science.gov (United States)

    Yahi, H.; Marticorena, B.; Thiria, S.; Chatenet, B.; Schmechtig, C.; Rajot, J. L.; Crepon, M.

    2013-12-01

    work aims at assessing the capability of passive remote-sensed measurements such as aerosol optical depth (AOD) to monitor the surface dust concentration during the dry season in the Sahel region (West Africa). We processed continuous measurements of AODs and surface concentrations for the period (2006-2010) in Banizoumbou (Niger) and Cinzana (Mali). In order to account for the influence of meteorological condition on the relationship between PM10 surface concentration and AOD, we decomposed the mesoscale meteorological fields surrounding the stations into five weather types having similar 3-dimensional atmospheric characteristics. This classification was obtained by a clustering method based on nonlinear artificial neural networks, the so-called self-organizing map. The weather types were identified by processing tridimensional fields of meridional and zonal winds and air temperature obtained from European Centre for Medium-Range Weather Forecasts (ECMWF) model output centered on each measurement station. Five similar weather types have been identified at the two stations. Three of them are associated with the Harmattan flux; the other two correspond to northward inflow of the monsoon flow at the beginning or the end of the dry season. An improved relationship has been found between the surface PM10 concentrations and the AOD by using a dedicated statistical relationship for each weather type. The performances of the statistical inversion computed on the test data sets show satisfactory skills for most of the classes, much better than a linear regression. This should permit the inversion of the mineral dust concentration from AODs derived from satellite observations over the Sahel.

  11. Final report of evaluation of dose and measurement of radon concentration

    International Nuclear Information System (INIS)

    1998-03-01

    A mean annual exposure to radon daughters in indoor air was estimated on the basis of measurement of radon concentration in indoor air in Japan from fiscal 1992 to 1996. Doses were estimated by UNSCEAR method. The representative values in this report show the mean values in whole Japan. Each dose in the local area was different reflecting the different concentration of radon daughters. However, the same parameters were used in each area. When mean annual dose of radon daughters was estimated, we used 15.5 Bq m -3 mean annual exposure to radon daughters in indoor air, 5 Bq m -3 that in outdoor air, 0.4 the equilibrium factor indoor, 0.6 the equilibrium factor outdoor and 0.9 of P. The model of UNSCEAR based on these above values gave 0.46 mSv y -1 mean annual dose of radon daughters which were consisted of from 0.38 mSv y -1 in Kanto district to 0.52 mSv y -1 Kyushu, Okinawa district. (S.Y.)

  12. Final report of evaluation of dose and measurement of radon concentration

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A mean annual exposure to radon daughters in indoor air was estimated on the basis of measurement of radon concentration in indoor air in Japan from fiscal 1992 to 1996. Doses were estimated by UNSCEAR method. The representative values in this report show the mean values in whole Japan. Each dose in the local area was different reflecting the different concentration of radon daughters. However, the same parameters were used in each area. When mean annual dose of radon daughters was estimated, we used 15.5 Bq m{sup -3} mean annual exposure to radon daughters in indoor air, 5 Bq m{sup -3} that in outdoor air, 0.4 the equilibrium factor indoor, 0.6 the equilibrium factor outdoor and 0.9 of P. The model of UNSCEAR based on these above values gave 0.46 mSv y{sup -1} mean annual dose of radon daughters which were consisted of from 0.38 mSv y{sup -1} in Kanto district to 0.52 mSv y{sup -1} Kyushu, Okinawa district. (S.Y.)

  13. Vitamin D - Dependent Rickets, Type II Case Report

    OpenAIRE

    Azemi, Mehmedali; Berisha, Majlinda; Ismaili-Jaha, Vlora; Kolgeci, Selim; Hoxha, Rina; Grajçevci-Uka, Violeta; Hoxha-Kamberi, Teuta

    2014-01-01

    Aim: The aim of this work the report of one case with vitamin D-dependent rickets, type II. Methods: Diagnosis has been established based on anamnesis, physical examination, laboratory findings and radiological examination. Results: A female child (age 25 months) has been hospitalized due to bone deformity, bone pain, alopecia and walking difficulties. The laboratory findings have revealed that the calcium values was low (1.20 mmol/L), phosphates in the reference value (1.30 mmol/L) the alkal...

  14. Maps on large-scale air quality concentrations in the Netherlands. Report on 2009

    International Nuclear Information System (INIS)

    Velders, G.J.M.; Aben, J.M.M.; Blom, W.F.; Diederen, H.S.M.A.; Geilenkirchen, G.P.; Jimmink, B.A.; Koekoek, A.F.; Koelemeijer, R.B.A.; Matthijsen, J.; Peek, C.J.; Van Rijn, F.J.A.; Van Schijndel, M.W.; Van der Sluis, O.C.; De Vries, W.J.

    2009-06-01

    In the Netherlands, the number of locations where the European limit values for particulate matter and nitrogen dioxide concentrations could be exceeded is lower than was estimated last year. The limit value for particulate matter, from 2011 onwards, is possibly be exceeded at only a few locations in the Netherlands, based on standing and proposed national and European policies. These locations are situated mainly in the Randstad area in the Netherlands, in the vicinity of motorways around the large cities, and close to stables in agricultural areas. The limit value for nitrogen dioxide, from 2015 onwards, is possibly to be exceeded along 100 kilometres of roads in cities and along 50 kilometres of motorways. Whether the limit values will actually be exceeded depends also on local policies and meteorological fluctuations. This estimate was based on large-scale concentration maps (called GCN maps) of air quality components, and on additional local contributions. The concentration maps provided the best possible estimate of large-scale air quality. The degree of uncertainty in local concentrations of particulate matter and nitrogen dioxide was estimated to be approximately 15 to 20%. This report presents the methods and emissions used for producing the GCN maps. It also shows the differences with respect to the maps of 2008. These maps are used by local, provincial and other authorities to define additional local measures. PBL would like to emphasise that uncertainties in the concentrations must be kept in mind when using these maps for planning, or when comparing concentrations with limit values. This also applies to the selecting of local measures to improve the air quality. The concentration maps are available online, at http://www. pbl.nl/gcn [nl

  15. Maps on large-scale air quality concentrations in the Netherlands. Report on 2010

    International Nuclear Information System (INIS)

    Velders, G.J.M.; Aben, J.M.M.; Diederen, H.S.M.A.; Drissen, E; Geilenkirchen, G.P.; Jimmink, B.A.; Koekoek, A.F.; Koelemeijer, R.B.A.; Matthijsen, J.; Peek, C.J.; Van Rijn, F.J.A.; De Vries, W.J.

    2010-06-01

    In the Netherlands, the number of locations for which the European limit values for nitrogen dioxide concentrations could be exceeded is larger than was estimated last year. The limit value, from 2015 onwards, might be exceeded along 100 to 150 kilometres of city roads and along about 100 kilometres of motorways, based on standing and proposed national and European policies, not taking local policies into account. The exceedances occur mainly in the Randstad area, along motorways around the large cities, and in streets within these cities. The number of locations is about twice as large as was estimated last year, as a result of new measurements of emissions from heavy-duty vehicles, and meeting the limit value in time may require additional national and local policies. The new estimates were based on large-scale concentration maps (called GCN maps) of air quality components, and on additional local contributions. The concentration maps provided the best possible estimate of large-scale air quality. The degree of uncertainty in local concentrations of particulate matter and nitrogen dioxide was estimated at approximately 15 to 20 per cent. This report presents the methods and emissions used for producing the GCN maps. It also shows the differences with the maps produced in 2009. These maps are used by local, provincial and other authorities to define additional local measures. The PBL would like to emphasise that uncertainties in the concentrations must be kept in mind when using these maps for planning, or when comparing concentrations with limit values. This also applies to the selecting of local measures to improve the air quality. The concentration maps are available online, at http://www.pbl.nl/gcn. Keywords: GCN; particulate matter; PM10; nitrogen dioxide; limit value. [nl

  16. Droplet evaporation and spread on waxy and hairy leaves associated with type and concentration of adjuvants.

    Science.gov (United States)

    Xu, Linyun; Zhu, Heping; Ozkan, H Erdal; Bagley, William E; Krause, Charles R

    2011-07-01

    Adjuvants can improve pesticide application efficiency and effectiveness. However, quantifications of the adjuvant-amended pesticide droplet actions on foliage, which could affect application efficiencies, are largely unknown. Droplet evaporation rates and spread on waxy or hairy leaves varied greatly with the adjuvant types tested. On waxy leaves, the wetted areas of droplets containing crop oil concentrate (COC) were significantly smaller than those containing modified seed oil (MSO), non-ionic surfactant (NIS) or oil surfactant blend (OSB), whereas the evaporation rates of COC-amended droplets were significantly higher. On hairy leaves, COC-amended droplets remained on top of the hairs without wetting the epidermis. When the relative concentration was 1.50, the wetted area of droplets with NIS was 9.2 times lower than that with MSO and 6.1 times lower than that with OSB. The wetted area increased as the adjuvant concentration increased. MSO- or OSB-amended droplets spread extensively on the hairy leaf surface until they were completely dried. These results demonstrated that the proper concentration of MSO, NIS or OSB in spray mixtures improved the homogeneity of spray coverage on both waxy and hairy leaf surfaces and could reduce pesticide use. This article is a US Government work and is in the public domain in the USA. Published 2011 by John Wiley & Sons, Ltd.

  17. Type 2 diabetes mellitus in a Nigerian child: a case report.

    Science.gov (United States)

    Otaigbe, B E; Imafidon, E E

    2011-09-01

    Type 2 diabetes mellitus initially said to be an adult disease is now reported in children and adolescents in the developed countries because of increased incidence of obesity and sedentary habits associated with westernization and lifestyle changes. There is a paucity of reports from Africa. A 9 year old overweight female with a BMI of 28 kg/m(2) and a strong family history of DM in at least two generations presented with polyuria and weight loss. The mother had gestational diabetes and is on oral hypoglycaemics. Fasting blood sugar was 11.9 mmol/l. Urinalysis had +1 of glucose, no ketones. She was managed with diet control and exercise. The patient has remained euglycaemic in the past two months without drugs and is losing weight. Type 2 diabetes mellitus is being reported in an obese Nigerian child with a family history of DM and high socio-economic class. Routine screening of overweight children with a family history of DM is recommended.

  18. Concentration ratios for BIOPATH: selection of the soil-to-plant concentration ratio database

    International Nuclear Information System (INIS)

    Grogan, H.A.

    1985-01-01

    In Switzerland, high-level radioactive waste is planned to be deposited in deep crystalline formations. 'BIOPATH' is the computer code which has been used to simulate the movement of radionuclides in the biosphere, in order to calculate the doses to man. The key parameter used in the model on which the code is based is the concentration ratio (CR). This specifies the transfer of individual radionuclides via the various foodchains, ultimately to man. Five types of CR are required for the model, namely soil to plant, intake by cattle to milk, intake by cattle to meat, intake by poultry to eggs and from water to fish. Each of these CR are discussed in turn; it is shown that soil to plant CR exhibit a variability that greatly exceeds that observed in the other types of CR and for this reason the report goes on to consider these in much closer detail. The different methods and experimental techniques used to derive soil to plant CR are examined and assessed, to allow evaluation of a meaningful data base for use in BIOPATH. The report concludes by examining the data available for each radionuclide in turn and listing a recommended CR for it, to input into the BIOPATH model. (author)

  19. Concentrator Photovoltaics

    CERN Document Server

    Luque, Antonio L

    2007-01-01

    Photovoltaic solar-energy conversion is one of the most promising technologies for generating renewable energy, and conversion of concentrated sunlight can lead to reduced cost for solar electricity. In fact, photovoltaic conversion of concentrated sunlight insures an efficient and cost-effective sustainable power resource. This book gives an overview of all components, e.g. cells, concentrators, modules and systems, for systems of concentrator photovoltaics. The authors report on significant results related to design, technology, and applications, and also cover the fundamental physics and market considerations. Specific contributions include: theory and practice of sunlight concentrators; an overview of concentrator PV activities; a description of concentrator solar cells; design and technology of modules and systems; manufacturing aspects; and a market study.

  20. Orthodontic treatment in adult with type I temporomandibular dysfunction : A case report

    Directory of Open Access Journals (Sweden)

    A Sai Prakash

    2012-01-01

    Full Text Available The relationship between occlusion and TMJ has been the subject of considerable controversy. It is widely believed that the TMJ signs and symptoms such as Joint pain, clicking, locking and headaches are secondary to abnormalities of occlusion, with actual derangement being uncommon. This case report is to put forward the hypothesis that, type I TMD is often due primarily to occlusal interferences for which orthodontic treatment is generally effective. This case report underlines the significance of fixed orthodontic appliance along with the anterior bite plane splint used in correction of type I TMD.

  1. Circulating asprosin concentrations are increased in type 2 diabetes mellitus and independently associated with fasting glucose and triglyceride.

    Science.gov (United States)

    Zhang, Lei; Chen, Chao; Zhou, Nan; Fu, Yuming; Cheng, Xingbo

    2017-11-03

    Asprosin has been identified as a novel hormone enriched in white adipose tissue and is pathologically increased in insulin-resistant mice and humans. However, information regarding the role of asprosin in type 2 diabetes mellitus (T2DM) remains unavailable. Via conducting a hospital-based study, we purposed to ascertain the potential relationship between circulating asprosin concentrations and T2DM. The study recruited 84 adults with T2DM and 86 controls with normal glucose tolerance. They matched in age, body mass index (BMI), and sex. Serum asprosin concentrations were measured via ELISA method. Compared to the controls, serum asprosin concentrations were significantly increased in the T2DM adults (Pglucose and triglyceride were independently associated with serum asprosin in T2DM. Asprosin concentrations are increased in adults with T2DM. The results suggest that asprosin might serve as a risk factor associated with the pathogenesis of T2DM, but not an ideal biomarker for predicting T2DM. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Case report of severe Cushing's syndrome in medullary thyroid cancer complicated by functional diabetes insipidus, aortic dissection, jejunal intussusception, and paraneoplastic dysautonomia: remission with sorafenib without reduction in cortisol concentration.

    Science.gov (United States)

    Hammami, Muhammad M; Duaiji, Najla; Mutairi, Ghazi; Aklabi, Sabah; Qattan, Nasser; Abouzied, Mohei El-Din M; Sous, Mohamed W

    2015-09-09

    Normalization of cortisol concentration by multikinase inhibitors have been reported in three patients with medullary thyroid cancer-related Cushing's syndrome. Aortic dissection has been reported in three patients with Cushing's syndrome. Diabetes insipidus without intrasellar metastasis, intestinal intussusception, and paraneoplastic dysautonomia have not been reported in medullary thyroid cancer. An adult male with metastatic medullary thyroid cancer presented with hyperglycemia, hypernatremia, hypokalemia, hypertension, acne-like rash, and diabetes insipidus (urine volume >8 L/d, osmolality 190 mOsm/kg). Serum cortisol, adrenocorticoitropic hormone, dehydroepiandrostenedione sulfate, and urinary free cortisol were elevated 8, 20, 4.4, and 340 folds, respectively. Pituitary imaging was normal. Computed tomography scan revealed jejunal intussusception and incidental abdominal aortic dissection. Sorafenib treatment was associated with Cushing's syndrome remission, elevated progesterone (>10 fold), normalization of dehydroepiandrostenedione sulfate, but persistently elevated cortisol concentration. Newly-developed proximal lower limb weakness and decreased salivation were associated with elevated ganglionic neuronal acetylcholine receptor (alpha-3) and borderline P/Q type calcium channel antibodies. Extreme cortisol concentration may have contributed to aortic dissection and suppressed antidiuretic hormone secretion; which combined with hypokalemia due cortisol activation of mineralocorticoid receptors, manifested as diabetes insipidus. This is the first report of paraneoplastic dysautonomia and jejunal intussusception in medullary thyroid cancer, they may be related to medullary thyroid cancer's neuroendocrine origin and metastasis, respectively. Remission of Cushing's syndrome without measurable reduction in cortisol concentration suggests a novel cortisol-independent mechanism of action or assay cross-reactivity. Normalization of dehydroepiandrostenedione

  3. N-3 polyunsaturated fatty acids improve lipoprotein particle size and concentration in Japanese patients with type 2 diabetes and hypertriglyceridemia: a pilot study.

    Science.gov (United States)

    Ide, Kana; Koshizaka, Masaya; Tokuyama, Hirotake; Tokuyama, Takahiko; Ishikawa, Takahiro; Maezawa, Yoshiro; Takemoto, Minoru; Yokote, Koutaro

    2018-03-15

    Patients with type 2 diabetes are at high risk for cardiovascular disease. Although hydroxymethylglutaryl-CoA reductase inhibitors (statins) can reduce cardiovascular events, residual risk remains even after target low-density lipoprotein cholesterol (LDL-C) levels have been achieved. Lipoprotein particle size and fraction changes are thought to contribute to such risks. The purpose of this study was to evaluate the effects of n-3 polyunsaturated fatty acids (n-3 PUFAs), predominantly eicosapentaenoic acid and docosahexaenoic acid, on lipoprotein particle size, concentration, and glycemic control in Japanese patients with type 2 diabetes and hypertriglyceridemia. This was a multicenter, prospective, open-label, single arm study. We enrolled 14 patients with type 2 diabetes and hypertriglyceridemia treated with statins and dipeptidyl peptidase-4 inhibitors with glycated hemoglobin (HbA1c) n-3 PUFAs for 12 weeks. Lipoprotein particle sizes, concentrations, lipoprotein insulin resistance (LPIR) scores, lipid profiles, HbA1c, and fasting plasma glucose (FPG) were measured before and after treatment. Lipoprotein profiles were measured by nuclear magnetic resonance spectroscopy. Data were analyzed using Wilcoxon signed-rank tests. Concentrations of total cholesterol (P n-3 PUFA administration. N-3 PUFAs decreased the size of very low-density lipoprotein (VLDL; P N-3 PUFAs partly improved atherogenic lipoprotein particle size and concentration, and produced less atherogenic lipoprotein subclass ratios in patients that achieved target LDL-C levels and glycemic control. These results suggest that n-3 PUFAs may reduce residual cardiovascular risk factors in statin-treated patients with type 2 diabetes and hypertriglyceridemia. The study was registered at UMIN-ID: UMIN000013776 .

  4. Maps on large-scale air quality concentrations in the Netherlands. Report on 2008

    International Nuclear Information System (INIS)

    Velders, G.J.M.; Aben, J.M.M.; Blom, W.F.; Van Dam, J.D.; Elzenga, H.E.; Geilenkirchen, G.P.; Hammingh, P.; Hoen, A.; Jimmink, B.A.; Koelemeijer, R.B.A.; Matthijsen, J.; Peek, C.J.; Schilderman, C.B.W.; Van der Sluis, O.C.; De Vries, W.J.

    2008-01-01

    Decrease expected in the number of locations exceeding the air quality limit values In the Netherlands, the number of locations were the European limit values for particulate matter and nitrogen dioxide will be exceeded is expected to decrease by 70-90%, in the period up to 2011, respectively 2015. The limit value for particulate matter from 2011 onwards, and for nitrogen dioxide from 2015 onwards, is expected to be exceeded at a small number of locations in the Netherlands, based on standing and proposed Dutch and European policies. These locations are situated mainly in the Randstad, Netherlands, in the vicinity of motorway around the large cities and in the busiest streets in large cities. Whether the limit values will actually be exceeded depends also on local policies and meteorological fluctuations. This estimate is based on large-scale concentration maps (called GCN maps) of air quality components and on additional local contributions. The concentration maps provide the best possible estimate of large-scale air quality. The degree of uncertainty about the local concentrations of particulate matter and nitrogen dioxide is estimated to be approximately 20%. This report presents the methods used to produce the GCN maps and the included emissions. It also shows the differences with respect to the maps of 2007. These maps are used by local, provincial and other authorities. MNP emphasises to keep the uncertainties in the concentrations in mind when using these maps for planning, or when comparing concentrations with limit values. This also applies to the selecting of local measures to improve the air quality. The concentration maps are available online, at http://www.mnp.nl/gcn.html [nl

  5. Haemophilus influenzae type B genital infection and septicemia in pregnant woman: a case report

    Directory of Open Access Journals (Sweden)

    Hosuru Subramanya Supram

    2014-06-01

    Full Text Available Haemophilus influenzae (H. influenzae type B a non-motile, aerobic, gram negative cocobacillus is a commensal of upper respiratory tract. Genitourinary infection due to H. influenzae has been reported but bacteremia associated with such infection appears to be rare. We report a case of 19 years young primigravida with complaints of amenorrhea of 32 weeks and 5 days, pyrexia, abdominal pain and blood stained discharge per vaginum. H. influenzae type B was recovered from the genital tract as well as blood of the mother indicating maternal septicemia. Septicemia caused by H. influenzae type B in pregnant women following vaginal colonization and infection is rare. It has been reported in many parts of world over the years; to the best of our knowledge this is the first reported case from Nepal. H. influenzae should be considered as a potential maternal, fetal, and neonatal pathogen.

  6. Prediction of ore fluid metal concentrations from solid solution concentrations in ore-stage calcite: Application to the Illinois-Kentucky and Central Tennessee Mississippi Valley-type districts

    Science.gov (United States)

    Smith-Schmitz, Sarah E.; Appold, Martin S.

    2018-03-01

    Knowledge of the concentrations of Zn and Pb in Mississippi Valley-type (MVT) ore fluids is fundamental to understanding MVT deposit origin. Most previous attempts to quantify the concentrations of Zn and Pb in MVT ore fluids have focused on the analysis of fluid inclusions. However, these attempts have yielded ambiguous results due to possible contamination from secondary fluid inclusions, interferences from Zn and Pb in the host mineral matrix, and uncertainties about whether the measured Zn and Pb signals represent aqueous solute or accidental solid inclusions entrained within the fluid inclusions. The purpose of the present study, therefore, was to try to determine Zn and Pb concentrations in MVT ore fluids using an alternate method that avoids these ambiguities by calculating Zn and Pb concentrations in MVT ore fluids theoretically based on their solid solution concentrations in calcite. This method was applied to the Illinois-Kentucky and Central Tennessee districts, which both contain ore-stage calcite. Experimental partition coefficient (D) values from Rimstidt et al. (1998) and Tsusue and Holland (1966), and theoretical thermodynamic distribution coefficient (KD) values were employed in the present study. Ore fluid concentrations of Zn were likely most accurately predicted by Rimstidt et al. (1998) D values, based on their success in predicting known fluid inclusion concentrations of Mg and Mn, and likely also most accurately predicted ore fluid concentrations of Fe. All four of these elements have a divalent ionic radius smaller than that of Ca2+ and form carbonate minerals with the calcite structure. For both the Illinois-Kentucky and the Central Tennessee district, predicted ore fluid Zn and Fe concentrations were on the order of up to 10's of ppm. Ore fluid concentrations of Pb could only be predicted using Rimstidt et al. (1998) D values. However, these concentrations are unlikely to be reliable, as predicted ore fluid concentrations of Sr and Ba

  7. Characterization of voic volume VOC concentration in vented TRU waste drums. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Liekhus, K.J.

    1994-12-01

    A test program has been conducted at the Idaho National Engineering Laboratory to demonstrate that the concentration of volatile organic compounds within the innermost layer of confinement in a vented waste drum can be estimated using a model incorporating diffusion and permeation transport principles and limited waste drum sampling data. This final report summarizes the experimental measurements and model predictions for transuranic waste drums containing solidified sludges and solid waste.

  8. Numerical and experimental investigation on a new type of compound parabolic concentrator solar collector

    International Nuclear Information System (INIS)

    Zheng, Wandong; Yang, Lin; Zhang, Huan; You, Shijun; Zhu, Chunguang

    2016-01-01

    Highlights: • A serpentine compound parabolic concentrator solar collector is proposed. • A mathematical model for the new collector is developed and verified by experiments. • The thermal efficiency of the collector can be up to 60.5% during the experiments. • The effects of key parameters on the thermal performance are mathematically studied. - Abstract: In order to improve the thermal efficiency, reduce the heat losses and achieve high freezing resistance of the solar device for space heating in cold regions, a new type of serpentine compound parabolic concentrator solar collector is presented in this paper, which is a combination of a compound parabolic concentrator solar collector and a flat plate solar collector. A detailed mathematical model for the new collector based on the analysis of heat transfer is developed and then solved by the software tool Matlab. The numerical results are compared with the experimental data and the maximum deviation is 8.07%, which shows a good agreement with each other. The experimental results show that the thermal efficiency of the collector can be as high as 60.5%. The model is used to predict the thermal performance of the new collector. The effects of structure and operating parameters on the thermal performance are mathematically discussed. The numerical and experimental results show that the new collector is more suitable to provide low temperature hot water for space heating in cold regions and the mathematical model will be much helpful in the designing and optimizing of the solar collectors.

  9. Concentration of bisphenol A in highly consumed canned foods on the U.S. market.

    Science.gov (United States)

    Noonan, Gregory O; Ackerman, Luke K; Begley, Timothy H

    2011-07-13

    Metal food and drink cans are commonly coated with epoxy films made from phenolic polymers produced from bisphenol A (BPA). It is well established that residual BPA monomer migrates into can contents during processing and storage. While a number of studies have reported BPA concentrations in foods from foreign markets and specialty foods on the U.S. market, very few peer-reviewed data for the BPA concentrations in canned food from the U.S. market were available. This study quantified BPA concentrations in 78 canned and two frozen food products from the U.S. market using an adaptation of a previously reported liquid chromatography-tandem mass spectrometry method. The tested products represented 16 different food types that are from the can food classifications that constitute approximately 65% of U.S. canned food sales and canned food consumption. BPA was detected in 71 of the 78 canned food samples but was not detected in either of the two frozen food samples. Detectable BPA concentrations across all foods ranged from 2.6 to 730 ng/g. Large variations in BPA concentrations were found between different products of the same food type and between different lots of the same product. Given the large concentration ranges, the only distinguishable trend was that fruits and tuna showed the lowest BPA concentrations. Experiments with fortified frozen vegetables and brine solutions, as well as higher BPA concentrations in canned food solids over liquid portions, clearly indicated that BPA partitions into the solid portion of foods.

  10. Relationship between self-reported adherence, antiretroviral drug concentration measurement and self-reported symptoms in patients treated for HIV-1 infection.

    Science.gov (United States)

    Fabbiani, Massimiliano; Di Giambenedetto, Simona; Cingolani, Antonella; Fanti, Iuri; Colafigli, Manuela; Tamburrini, Enrica; Cauda, Roberto; Navarra, Pierluigi; De Luca, Andrea; Murri, Rita

    2016-01-01

    The aim of the study was to explore relationships between self-reported adherence, antiretroviral drug concentration measurement (TDM) and self-reported symptoms. We systematically administered to human immunodeficiency (HIV)-infected outpatients a questionnaire evaluating measures of self-reported adherence (missing doses during last week, deviations from the prescribed timing of therapy, self-initiated discontinuations for > 24 or 48 h, exhausting drugs and present sense of how patients are taking therapy) and a panel of referred symptoms (a symptom score was built summing self-reported scores for each listed symptom). We selected patients who completed the questionnaire and also had a TDM (mainly reflecting adherence in the past few days or weeks), thus comparing these two tools as measures of adherence. A total of 130 patients (64.6% males, median age 44 years, 76.2% with HIV RNA HIV RNA symptom score was associated with a lower self-reported adherence and with a higher proportion of undetectable drug levels. Self-reported adherence and TDM showed a correlation and seemed to be comparable tools for adherence estimation. Self-reported symptoms were associated with lower adherence and undetectable drug levels.

  11. Studies of post-elution concentration of 99m-Tc eluted from a gel type chromatographic generator

    International Nuclear Information System (INIS)

    Suzuki, Katia N.; Osso Junior, Joao Alberto

    2007-01-01

    The radiopharmaceuticals most used in Diagnostic Nuclear Medicine are those labeled with the metastable technetium ( 99m Tc) due to its ideal physical properties of decay (t 1/2 6.01 h, Eγ 140 keV), low cost and availability facilitated through the commercial generator 99 Mo / 99m Tc. This radionuclide is formed by the β - decay of 99 Mo adsorbed on an alumina column of the generator and collected in the form of sodium pertechnetate (Na 99m TcO 4 ) by elution with saline solution (0.9%). The Radiopharmacy Center (CR) of the IPEN-CNEN/SP developed a gel type chromatographic generator of MoZr with 99 Mo produced by 98 Mo(n, γ) 99 Mo reaction that occurs in IEA-R1 Nuclear Reactor. The gel is composed of zirconium molybdate with elution volume of 12 ml with an activity of 11100 MBq (300 mCi) producing a radioactive concentration of 925 MBq (34 mCi) / ml. The fission generator gives a higher radioactive concentration around 1850 MBq (69 mCi) / ml. The aim of this work is to study a system of post-elution concentration using ion exchange cartridges in tandem (cation - anion) for the attainment of a high enough radioactive concentration to meet the demand of market, with a proved quality. This system of concentration will be made based in the technique of solid phase extraction (SPE) using commercial cartridges of extraction, which contains the solid phase and eluent saline solution (0.9%). As the eluent results of this system used in the gel generator of MoZr will be compared with the fission generator currently produced by IPEN-CNEN/SP. (author)

  12. Waste Tank Organic Safety Project organic concentration mechanisms task. FY 1994 progress report

    International Nuclear Information System (INIS)

    Gerber, M.A.

    1994-09-01

    The Pacific Northwest Laboratory (PNL), Waste Tank Organic Safety Project is conducting research to support Westinghouse Hanford Company's (WHC) Waste Tank Safety Program, sponsored by the U.S. Department of Energy's Tank Farm Project Office. The goal of PNL's program is to provide a scientific basis for analyzing organics in Hanford's underground storage tanks (USTs) and for determining whether they are at concentrations that pose a potentially unsafe condition. Part of this research is directed toward determining what organic concentrations are safe by conducting research on organic aging mechanisms and waste energetics to assess the conditions necessary to produce an uncontrolled energy release in tanks due to reactions between the organics and the nitrate and nitrate salts in the tank wastes. The objective of the Organic Concentration Mechanisms Task is to assess the degree of localized enrichment of organics to be expected in the USTs due to concentration mechanisms. This report describes the progress of research conducted in FY 1994 on two concentration mechanisms of interest to the tank safety project: (1) permeation of a separate organic liquid phase into the interstitial spaces of the tank solids during the draining of free liquid from the tanks; and (2) concentration of organics on the surfaces of the solids due to adsorption. Three experiments were conducted to investigate permeation of air and solvent into a sludge simulant that is representative of single-shell tank sludge. The permeation behavior of air and solvent into the sludge simulant can be explained by the properties of the fluid pairs (air/supernate and solvent supernate) and the sludge. One important fluid property is the interfacial tension between the supernate and either the solvent or air. In general, the greater the interfacial tension between two fluids, the more difficult it will be for the air or solvent to displace the supernate during dewatering of the sludge

  13. Type 2 Diabetes mellitus in a Nigerian child: a case report | Otaigbe ...

    African Journals Online (AJOL)

    Background: Type 2 diabetes mellitus initially said to be an adult disease is now reported in children and adolescents in the developed countries because of increased incidence of obesity and sedentary habits associated with westernization and lifestyle changes. There is a paucity of reports from Africa Method: A 9year old ...

  14. Modeled atmospheric radon concentrations from uranium mines

    Energy Technology Data Exchange (ETDEWEB)

    Droppo, J.G.

    1985-04-01

    Uranium mining and milling operations result in the release of radon from numerous sources of various types and strengths. The US Environmental Protection Agency (EPA) under the Clean Air Act, is assessing the health impact of air emissions of radon from underground uranium mines. In this case, the radon emissions may impact workers and residents in the mine vicinity. To aid in this assessment, the EPA needs to know how mine releases can affect the radon concentrations at populated locations. To obtain this type of information, Pacific Northwest Laboratory used the radon emissions, release characteristics and local meterological conditions for a number of mines to model incremental radon concentrations. Long-term, average, incremental radon concentrations were computed based on the best available information on release rates, plume rise parameters, number and locations of vents, and local dispersion climatology. Calculations are made for a model mine, individual mines, and multiple mines. Our approach was to start with a general case and then consider specific cases for comparison. A model underground uranium mine was used to provide definition of the order of magnitude of typical impacts. Then computations were made for specific mines using the best mine-specific information available for each mine. These case study results are expressed as predicted incremental radon concentration contours plotted on maps with local population data from a previous study. Finally, the effect of possible overlap of radon releases from nearby mines was studied by calculating cumulative radon concentrations for multiple mines in a region with many mines. The dispersion model, modeling assumptions, data sources, computational procedures, and results are documented in this report. 7 refs., 27 figs., 18 tabs.

  15. Modeled atmospheric radon concentrations from uranium mines

    International Nuclear Information System (INIS)

    Droppo, J.G.

    1985-04-01

    Uranium mining and milling operations result in the release of radon from numerous sources of various types and strengths. The US Environmental Protection Agency (EPA) under the Clean Air Act, is assessing the health impact of air emissions of radon from underground uranium mines. In this case, the radon emissions may impact workers and residents in the mine vicinity. To aid in this assessment, the EPA needs to know how mine releases can affect the radon concentrations at populated locations. To obtain this type of information, Pacific Northwest Laboratory used the radon emissions, release characteristics and local meterological conditions for a number of mines to model incremental radon concentrations. Long-term, average, incremental radon concentrations were computed based on the best available information on release rates, plume rise parameters, number and locations of vents, and local dispersion climatology. Calculations are made for a model mine, individual mines, and multiple mines. Our approach was to start with a general case and then consider specific cases for comparison. A model underground uranium mine was used to provide definition of the order of magnitude of typical impacts. Then computations were made for specific mines using the best mine-specific information available for each mine. These case study results are expressed as predicted incremental radon concentration contours plotted on maps with local population data from a previous study. Finally, the effect of possible overlap of radon releases from nearby mines was studied by calculating cumulative radon concentrations for multiple mines in a region with many mines. The dispersion model, modeling assumptions, data sources, computational procedures, and results are documented in this report. 7 refs., 27 figs., 18 tabs

  16. Bilateral dystonia in type 1 diabetes: a case report

    Directory of Open Access Journals (Sweden)

    Yasuhara Akihiro

    2008-11-01

    Full Text Available Abstract Introduction Diabetic hemichorea-hemiballismus is a rare complication of type 2 diabetes. Here, we report a case with type 1 diabetes, with hemichorea and bilateral dystonia manifested as hyperglycemia-induced involuntary movement. Case presentation A 62-year-old Japanese women with body weight loss of 30 kg during the past year developed symptoms of thirst, polydipsia and polyuria. She also presented with hemichorea and bilateral dystonia for 5 days and extremely high plasma glucose (774 mg/dl, hemoglobin A1c (21.2% and glycated albumin (100% with ketosis. Based on the presence of glutamic acid decarboxylase antibodies (18,000 U/ml; normal Conclusion Hyperglycemia-induced involuntary movement is one of the manifestations of dystonia and hemichorea-hemiballism.

  17. Highly concentrating Fresnel lenses

    International Nuclear Information System (INIS)

    Kritchman, E.M.; Friesem, A.A.; Yekutieli, G.

    1979-01-01

    A new type of concave Fresnel lens capable of concentrating solar radiation very near the ultimate concentration limit is considered. The differential equations that describe the lens are solved to provide computed solutions which are then checked by ray tracing techniques. The performance (efficiency and concentration) of the lens is investigated and compared to that of a flat Fresnel lens, showing that the new lens is preferable for concentrating solar radiation. (author)

  18. Report on the coal type committee meetings in fiscal 1988; 1989 nendo tanshu iinkai hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-03-01

    This paper is a report on the coal type committee meetings in fiscal 1988. It summarizes the report mainly on the data distributed at the first and second coal type committee meetings. It describes liquefaction performance tests on Chinese coals in the coal type selection and investigation. In order to develop jointly by Japan and China the coal liquefaction technology, liquefaction tests have been performed on Chinese coals since fiscal 1982 by using the small continuous testing equipment (0.1 t/d) installed in the Beijing Soot and Coal Science Research Institute. The test is now in the third phase. The first sub-committee meeting reported the result on the Shenmu Simengou coal. The coal type investigation has analyzed coal samples collected from the world, classified them into brown coal, sub-bituminous coal of low coal rank, sub-bituminous coal, highly volatile bituminous coal of low coal rank, and highly volatile bituminous coal, and presented a list of candidate coals for liquefaction. Regarding the liquefaction performance tests on Chinese coals, the second coal type committee meeting reported the result on the Fuxin Qinghemen coal, and the result on the Tianzhu coal as revealed by using the NEDOL process BSU. The paper also presents the interim report on the research achievements in fiscal 1988 on the liquefaction performance tests on Chinese coals and the research achievements of the investigation and study in fiscal 1988 on the treatment technologies for coals used for coal gasification 'coal type selection and investigation'. (NEDO)

  19. Report on the coal type committee meetings in fiscal 1988; 1989 nendo tanshu iinkai hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-03-01

    This paper is a report on the coal type committee meetings in fiscal 1988. It summarizes the report mainly on the data distributed at the first and second coal type committee meetings. It describes liquefaction performance tests on Chinese coals in the coal type selection and investigation. In order to develop jointly by Japan and China the coal liquefaction technology, liquefaction tests have been performed on Chinese coals since fiscal 1982 by using the small continuous testing equipment (0.1 t/d) installed in the Beijing Soot and Coal Science Research Institute. The test is now in the third phase. The first sub-committee meeting reported the result on the Shenmu Simengou coal. The coal type investigation has analyzed coal samples collected from the world, classified them into brown coal, sub-bituminous coal of low coal rank, sub-bituminous coal, highly volatile bituminous coal of low coal rank, and highly volatile bituminous coal, and presented a list of candidate coals for liquefaction. Regarding the liquefaction performance tests on Chinese coals, the second coal type committee meeting reported the result on the Fuxin Qinghemen coal, and the result on the Tianzhu coal as revealed by using the NEDOL process BSU. The paper also presents the interim report on the research achievements in fiscal 1988 on the liquefaction performance tests on Chinese coals and the research achievements of the investigation and study in fiscal 1988 on the treatment technologies for coals used for coal gasification 'coal type selection and investigation'. (NEDO)

  20. Evaluation of resistant starch, glycemic index and fortificants content of premix rice coated with various concentrations and types of edible coating materials

    Science.gov (United States)

    Yulianto, W. A.; Susiati, A. M.; Adhini, H. A. N.

    2018-01-01

    The incidence of diabetes in Indonesia has been increasing year by year. Diets with a low glycemic index and high resistant starch foods can assist diabetics in controlling their blood glucose levels. Diabetics are known to have micro-nutrient deficiencies of chromium, magnesium and vitamin D that can be overcome by consuming parboiled rice fortified by use of a coating method. The fortification of parboiled rice (premix rice) can be achieved by coating with HPMC (hydroxypropyl methyl cellulose), MC (methyl cellulose), CMC (carboxyl methyl cellulose), gum arabic and rice starch. This research aimed to evaluate the levels of resistant starch, glycemic index and fortificants of premix rice coated with different concentrations and types of edible coating materials. This research used completely randomized design, with treatments to the concentrations and the types of edible coating (HPMC, CMC, MC, gum arabic and rice starch). The concentrations of edible coating were 0.15%, 0.2% and 0.25% for cellulose derivative coatings; 25%, 30%, 35% for gum arabic and 2%, 3.5% and 5% for rice starch. This research shows that fortified premix rice coated with various concentrations and types of edible coating materials is high in resistant starch and has a low glycemic index. The coating treatment affects the levels of magnesium and vitamin D, but does not affect the levels of chromium in parboiled rice. The premix rice with a low glycemic index and high nutrient content (chromium, magnesium and vitamin D) was premix rice coated by CMC 0.25% and HPMC 0.25% with glycemic indeces of 39.34 and 38.50, respectively.

  1. Animal type melanoma: a report of two cases

    Directory of Open Access Journals (Sweden)

    Mariângela Esther Alencar Marques

    2010-08-01

    Full Text Available Dificuldade potencial no diagnóstico histológico de melanomas é a dificuldade em reconhecer variantes pouco frequentes de melanoma. Entre elas, as mais desafiantes incluem exemplos de melanoma desmoplásico, melanoma nevoide, o chamado "melanoma de desvio mínimo", melanomas com proeminente síntese de pigmento ou "melanoma tipo animal" e o nevo azul maligno. Os autores descrevem dois casos de melanoma tipo animal e discute-se a importância do diagnóstico diferencial clinico-histopatológico nesses casos.A potential diagnostic pitfall in the histological assessment of melanomas is the difficulty in recognizing unusual melanoma variants. Among them, the most challenging examples comprise desmoplastic melanomas, nevoid melanomas, the so-called minimal-deviation melanoma, melanomas with prominent pigment synthesis or animal-type melanoma, and the malignant blue nevus. Two cases of animal type melanoma are reported and the importance of clinical-histopathological differential diagnosis is discussed.

  2. Optimized concentrating/passive tracking solar collector. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sterne, K E; Johnson, A L; Grotheer, R H

    1979-01-01

    A concentrating solar collector having about half the material cost of other collectors with similar performance is described. The selected design is a Compound Parabolic Concentrator (CPC) which concentrates solar energy throughout the year without requiring realignment. Output is a fluid heated to 100/sup 0/C with good efficiency. The optical design of the reflector surface was optimized, yielding a 2.0:1 concentration ratio with a 60/sup 0/C acceptance angle and a low profile. Double glazing was chosen consisting of a polyester film outer glazing and an inner glazing of glass tubes around the absorbers. The selectively coated steel absorber tubes are connected in series with flexible plastic tubing. Much development effort went into the materials for the reflector subassembly. A laminate of metalized plastic film over plaster was chosen for the reflective surface. The reflector is rigidized by attaching filled epoxy header plates at each end. Aluminum side rails and an insulating back complete the structure. The finished design resulted in a material cost of $21.40 per square meter in production quantities. Performance testing of a prototype produced a 50% initial efficiency rating. This is somewhat lower than expected, and is due to materials and processes used in the prototype for the outer glazing, reflective surface and absorber coating. However, the efficiency curve drops only slightly with increasing temperature differential, showing the inherent advantage of the concentrator over flat plate collectors.

  3. Test report dot7A type A liquid packaging

    Energy Technology Data Exchange (ETDEWEB)

    Ketusky, E. T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Brandjes, C. [Ameriphysics LLC, Knoxville, TN (United States); Benoit, T. J. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-09-19

    This section presents a general description of the DOT Specification 7A Type A liquid content packaging (HVYTAL), the liquid content evaluated as its payload, acceptable payload shipping configurations and features special to its use. This test report documents compliance with the regulatory safety requirements of 49 CFR Parts 173.24, 173.24a, 173.27, 173.410, 173.412, 173.461 – 173.466 and 178.350.

  4. Nodular type of muscular sarcoidosis : a case report

    International Nuclear Information System (INIS)

    Chae, Soo Hyun; Kim, Hong Soo; Park, Sook Hee; Kim, Sung Me

    1999-01-01

    Muscular involvement of sarcoidosis is rare and occurs in two forms:nodular and myopathic. In the nodular variety, lesions are long and extend along muscle fibers. Axial MR imaging reveals a star-shaped central structure of decreased signal intensity. Sagittal and coronal MR images show three stripes:an inner stripe of decreased signal intensity and outer stripes of increased signal intensity. Longitudinal sonography shows an echogenic inner stripe and hypoechoic outer stripes. We report a case of nodular- type muscular sarcoidosis in a 53-year-old man, describing the findings of MRI and ultrasonography

  5. Laryngeal and tracheal anomalies in an infant with oral-facial-digital syndrome type VI (Varadi-Papp): report of a transitional type

    International Nuclear Information System (INIS)

    Hayes, Laura L.; Palasis, Susan; Simoneaux, Stephen F.; Niyazov, Dmitriy M.

    2008-01-01

    The oral-facial-digital syndromes (OFDS) comprise a group of disorders involving malformations of the mouth, face, and digits. There are 13 subtypes of the OFDS, and much overlap exists among OFDS patients. Distinct syndromes such as Joubert and Pallister-Hall display many of the same features. This report describes an infant with abnormalities including a hypoplastic/absent cerebellar vermis and forked third metacarpals, consistent with a diagnosis of OFDS type VI (Varadi-Papp). The girl's abnormalities also included malformations of the larynx and trachea, findings never before described in type VI but described in other OFDS subtypes and similar syndromes. Our patient represents a transitional OFDS type, further supporting evidence of a common molecular pathway among these disorders. This report highlights the importance of the radiologist's role in diagnosis. (orig.)

  6. Barrier properties of PE, PP and EVA (nano)composites - The influence of filler type and concentration

    Energy Technology Data Exchange (ETDEWEB)

    Merinska, D.; Kalendova, A. [Department of Polymer Engineering, Faculty of Technology, Tomas Bata University in Zlin, Nam. T. G. Masaryka 275, 762 72 Zlin, Czech Republic and Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Nad Ovcirnou 3685, 760 0 (Czech Republic); Tesarikova, A. [Department of Polymer Engineering, Faculty of Technology, Tomas Bata University in Zlin, Nam. T. G. Masaryka 275, 762 72 Zlin (Czech Republic)

    2014-05-15

    Nanocomposite materials with layered clay used as nanofiller and polyethylene (PE), polypropylene (PP) and copolymer ethylene and vinyl acetate matrix (EVA, the content of VA component 19 wt. %) were prepared by compounding the individual components in Brabender kneader. The MMT Na+ and four types of commercial products such as Nanofil N 5 and N3000, Cloisite 93A and 30B were used as nanofillers. Next to the clays microprecipitated CaHCO{sub 3}, nanosilica and Halloysite tubes were used. The quantity of all the above-mentioned (nano)fillers was 1, 3 and 5 wt. % in relation to the content of montmorillonite. The aim was to evaluate the influence of (nano)filler type and concentration on nanocomposite barrier properties. The morphology of nanocomposite samples was examined by means of XRD analysis illustrated by transmission electronic microscopy TEM. Furthermore, permeability for O{sub 2} and CO{sub 2} were observed.

  7. Nuclear waste treatment - Studying the mixed ion type effects and concentration on the behaviour of oxide dispersions

    International Nuclear Information System (INIS)

    Omokanye, Qanitalillahi; Biggs, Simon

    2007-01-01

    In order to gain good control over a particulate dispersion it is necessary to accurately characterise the strength of inter-particle forces that may be operating. Such control is not routinely used, as yet, in the nuclear industry despite the possible benefits. We are investigating the impact of mixed electrolyte systems, for example NaCl and Na 2 SO 4 , on the stability of oxide simulant particle dispersions. The electro-acoustic zeta potentials and shear yield stresses for concentrated dispersions have been measured across a range of pH conditions and electrolyte concentrations (0.001 M - 1.0 M). This paper summarizes initial data from these studies showing how the shear yield stress of concentrated aqueous oxide particle dispersions, can be adjusted through regulation of pH and the addition of background electrolytes (salt). The yield stress as a function of pH for these dispersions in mixed electrolytes showed a direct correlation with corresponding measurements of the zeta potential. Changes in the background electrolyte concentration or type were seen to cause a shift in the position of the isoelectric point (iep). Measurements of the shear yield stress showed a maximum at the iep corresponding to the position of maximum instability in the suspension. The consequences of these data for the efficient treatment of solid-liquid systems will be discussed. (authors)

  8. Hall-effect measurements of metalorganic vapor-phase epitaxy-grown p-type homoepitaxial GaN layers with various Mg concentrations

    Science.gov (United States)

    Horita, Masahiro; Takashima, Shinya; Tanaka, Ryo; Matsuyama, Hideaki; Ueno, Katsunori; Edo, Masaharu; Takahashi, Tokio; Shimizu, Mitsuaki; Suda, Jun

    2017-03-01

    Mg-doped p-type gallium nitride (GaN) layers with doping concentrations in the range from 6.5 × 1016 cm-3 (lightly doped) to 3.8 × 1019 cm-3 (heavily doped) were investigated by Hall-effect measurement for the analysis of hole concentration and mobility. p-GaN was homoepitaxially grown on a GaN free-standing substrate by metalorganic vapor-phase epitaxy. The threading dislocation density of p-GaN was 4 × 106 cm-2 measured by cathodoluminescence mapping. Hall-effect measurements of p-GaN were carried out at a temperature in the range from 130 to 450 K. For the lightly doped p-GaN, the acceptor concentration of 7.0 × 1016 cm-3 and the donor concentration of 3.2 × 1016 cm-3 were obtained, where the compensation ratio was 46%. We also obtained the depth of the Mg acceptor level to be 220 meV. The hole mobilities of 86, 31, 14 cm2 V-1 s-1 at 200, 300, 400 K, respectively, were observed in the lightly doped p-GaN.

  9. Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris

    Directory of Open Access Journals (Sweden)

    Colby eMoore

    2014-06-01

    Full Text Available Northern elephant seals (Mirounga angustirostris (NES are known to be deep, long-duration divers and to sustain long-repeated patterns of breath-hold, or apnea. Some phocid dives remain within the bounds of aerobic metabolism, accompanied by physiological responses inducing lung compression, bradycardia and peripheral vasoconstriction. Current data suggest an absence of type IIb fibers in pinniped locomotory musculature. To date, no fiber type data exist for NES, a consummate deep diver. In this study, NES were biopsied in the wild. Ontogenetic changes in skeletal muscle were revealed through succinate dehydrogenase (SDH based fiber typing. Results indicated a predominance of uniformly shaped, large type I fibers and elevated myoglobin (Mb concentrations in the longissimus dorsi (LD muscle of adults. No type II muscle fibers were detected in any adult sampled. This was in contrast to the juvenile animals that demonstrated type II myosin in Western Blot analysis, indicative of an ontogenetic change in skeletal muscle with maturation. These data support previous hypotheses that the absence of type II fibers indicates reliance on aerobic metabolism during dives, as well as a depressed metabolic rate and low energy locomotion. We also suggest that the lack of type IIb fibers (adults may provide a protection against ischemia reperfusion (IR injury in vasoconstricted peripheral skeletal muscle.

  10. Predictors of Indoor Radon Concentrations in Pennsylvania, 1989-2013.

    Science.gov (United States)

    Casey, Joan A; Ogburn, Elizabeth L; Rasmussen, Sara G; Irving, Jennifer K; Pollak, Jonathan; Locke, Paul A; Schwartz, Brian S

    2015-11-01

    Radon is the second-leading cause of lung cancer worldwide. Most indoor exposure occurs by diffusion of soil gas. Radon is also found in well water, natural gas, and ambient air. Pennsylvania has high indoor radon concentrations; buildings are often tested during real estate transactions, with results reported to the Department of Environmental Protection (PADEP). We evaluated predictors of indoor radon concentrations. Using first-floor and basement indoor radon results reported to the PADEP between 1987 and 2013, we evaluated associations of radon concentrations (natural log transformed) with geology, water source, building characteristics, season, weather, community socioeconomic status, community type, and unconventional natural gas development measures based on drilled and producing wells. Primary analysis included 866,735 first measurements by building, with the large majority from homes. The geologic rock layer on which the building sat was strongly associated with radon concentration (e.g., Axemann Formation, median = 365 Bq/m3, IQR = 167-679 vs. Stockton Formation, median = 93 Bq/m3, IQR = 52-178). In adjusted analysis, buildings using well water had 21% higher concentrations (β = 0.191, 95% CI: 0.184, 0.198). Buildings in cities (vs. townships) had lower concentrations (β = -0.323, 95% CI: -0.333, -0.314). When we included multiple tests per building, concentrations declined with repeated measurements over time. Between 2005 and 2013, 7,469 unconventional wells were drilled in Pennsylvania. Basement radon concentrations fluctuated between 1987 and 2003, but began an upward trend from 2004 to 2012 in all county categories (p Pennsylvania, 1989-2013. Environ Health Perspect 123:1130-1137; http://dx.doi.org/10.1289/ehp.1409014.

  11. Mandatory Reporting Laws and Identification of Child Abuse and Neglect: Consideration of Differential Maltreatment Types, and a Cross-Jurisdictional Analysis of Child Sexual Abuse Reports

    Directory of Open Access Journals (Sweden)

    Ben Mathews

    2014-08-01

    Full Text Available Mandatory reporting laws have been created in many jurisdictions as a way of identifying cases of severe child maltreatment on the basis that cases will otherwise remain hidden. These laws usually apply to all four maltreatment types. Other jurisdictions have narrower approaches supplemented by differential response systems, and others still have chosen not to enact mandatory reporting laws for any type of maltreatment. In scholarly research and normative debates about mandatory reporting laws and their effects, the four major forms of child maltreatment—physical abuse, sexual abuse, emotional abuse, and neglect—are often grouped together as if they are homogenous in nature, cause, and consequence. Yet, the heterogeneity of maltreatment types, and different reporting practices regarding them, must be acknowledged and explored when considering what legal and policy frameworks are best suited to identify and respond to cases. A related question which is often conjectured upon but seldom empirically explored, is whether reporting laws make a difference in case identification. This article first considers different types of child abuse and neglect, before exploring the nature and operation of mandatory reporting laws in different contexts. It then posits a differentiation thesis, arguing that different patterns of reporting between both reporter groups and maltreatment types must be acknowledged and analysed, and should inform discussions and assessments of optimal approaches in law, policy and practice. Finally, to contribute to the evidence base required to inform discussion, this article conducts an empirical cross-jurisdictional comparison of the reporting and identification of child sexual abuse in jurisdictions with and without mandatory reporting, and concludes that mandatory reporting laws appear to be associated with better case identification.

  12. Subinhibitory concentration of kanamycin induces the Pseudomonas aeruginosa type VI secretion system.

    Directory of Open Access Journals (Sweden)

    Cerith Jones

    Full Text Available Pseudomonas aeruginosa is a Gram-negative bacterium found in natural environments including plants, soils and warm moist surfaces. This organism is also in the top ten of nosocomial pathogens, and prevalent in cystic fibrosis (CF lung infections. The ability of P. aeruginosa to colonize a wide variety of environments in a lasting manner is associated with the formation of a resistant biofilm and the capacity to efficiently outcompete other microorganisms. Here we demonstrate that sub-inhibitory concentration of kanamycin not only induces biofilm formation but also induces expression of the type VI secretion genes in the H1-T6SS cluster. The H1-T6SS is known for its role in toxin production and bacterial competition. We show that the antibiotic induction of the H1-T6SS only occurs when a functional Gac/Rsm pathway is present. These observations may contribute to understand how P. aeruginosa responds to antibiotic producing competitors. It also suggests that improper antibiotic therapy may enhance P. aeruginosa colonization, including in the airways of CF patients.

  13. Soil and pasture P concentration in a Fraxinus excelsior L. silvopastoral system fertilised with different types of sewage sludge

    Science.gov (United States)

    Ferreiro-Domínguez, Nuria; Nair, Vimala; Rigueiro-Rodríguez, Antonio; Rosa Mosquera-Losada, María

    2015-04-01

    In Europe, sewage sludge should be stabilised before using as fertiliser in agriculture. Depending on the stabilisation process that is used, sewage sludge has different characteristics, nutrient contents and soil nutrient incorporation rates. Sewage sludge is usually applied on a plant-available N or total metal concentration basic, and therefore, P concentrations can be well above crop needs. Leaching of excess P can threaten surface and ground waters with eutrophication. In this context, recent studies have demonstrated that the implementation of agroforestry systems could reduce the P leaching risk compared with conventional agricultural systems due to the different localisation of tree and crop roots which enhance nutrient uptake. The aim of this study was to evaluate during three consecutive years the effect of municipal sewage sludge stabilised by anaerobic digestion, composting, and pelletisation on concentration of P in soil and pasture compared to control treatments (mineral and no fertilisation) in a silvopastoral system established under Fraxinus excelsior L. in Galicia (Spain). The results showed that at the beginning of the study, the fertilisation with mineral increased more the total and available P in soil than the fertilisation with sewage sludge probably because the sludge nutrient release rate is slower than those from mineral fertilisers. The increment of soil available P caused by the mineral fertiliser implied an improvement of the P concentration in the pasture. However, in the last year of the experiment it was observed a positive effect of the fertilisation with pelletised sludge on the concentration of P in pasture compared with the composted sludge and the mineral fertiliser probably due to the annual application of this type of sludge. Therefore, the establishment of silvopastoral systems and their fertilisation with pelletized sludge should be recommended because the pelletized sludge increases the concentration of P in the pasture and

  14. TXRF 'measurements' of concentration distribution below the detection limit

    International Nuclear Information System (INIS)

    Kubala-Kukus, A.; Banas, D.; Braziewicz, J.; Majewska, U.; Mrowczynski, S.; Pajek, M.

    2000-01-01

    We demonstrate that a shape of the concentration distribution of the element in a set of samples, as measured by the TXRF method, can be determined even for the concentrations below the detection limit (DL). This can be done, when the measurements reporting the concentration below DL level are included properly in the analysis of the results. The method developed for such correction is presented and discussed. It is demonstrated that this correction is particularly important when the studied concentrations are close to the DL level of the method, which is a common case for TXRF. In the paper a precision of the developed correction is discussed in details, by using the results of numerical simulations of experiments for different concentration distributions and number of performed measurements. It is demonstrated that the factor, which limits the accuracy of the correction, is the number of measurements, not the correction procedure itself. The applicability and importance of the developed correction is demonstrated for routine TXRF analysis of different types of samples of bio-medical interest. (author)

  15. The performance of solar collector CPC (compound parabolic concentrator) type with three pipes covered by glass tubes

    Science.gov (United States)

    Gaos, Yogi Sirodz; Yulianto, Muhamad; Juarsa, Mulya; Nurrohman, Marzuki, Edi; Yuliaji, Dwi; Budiono, Kabul

    2017-03-01

    Indonesia is a tropical country that has potential energy of solar radiation worth of 4.5 until 4.8 kWh/m2. However, this potential has not been utilized regularly. This paper will discuss the performance of solar collector compound parabolic concentrator (CPC) type with water as the working fluid. This CPC solar collector utilized three pipes covered by glass tubes. This paper has contribution to provide the temperature achievement between three pipes covered by glass tubes with and without glass cover of solar collector CPC type. The research conducted by varying the water flow rate of 1 l/m up to 6 l/m with three pipes arranged in series and parallel. From the results, the used of solar collector CPC type in the current study shows that the decrease of solar radiation, which was caused by climate change, did not influence the heat absorbance by water in the pipe. Therefore, the design of the solar collector in this research has potential to be used in future when solar radiation are used as the energy source.

  16. Discrimination of source reactor type by multivariate statistical analysis of uranium and plutonium isotopic concentrations in unknown irradiated nuclear fuel material.

    Science.gov (United States)

    Robel, Martin; Kristo, Michael J

    2008-11-01

    The problem of identifying the provenance of unknown nuclear material in the environment by multivariate statistical analysis of its uranium and/or plutonium isotopic composition is considered. Such material can be introduced into the environment as a result of nuclear accidents, inadvertent processing losses, illegal dumping of waste, or deliberate trafficking in nuclear materials. Various combinations of reactor type and fuel composition were analyzed using Principal Components Analysis (PCA) and Partial Least Squares Discriminant Analysis (PLSDA) of the concentrations of nine U and Pu isotopes in fuel as a function of burnup. Real-world variation in the concentrations of (234)U and (236)U in the fresh (unirradiated) fuel was incorporated. The U and Pu were also analyzed separately, with results that suggest that, even after reprocessing or environmental fractionation, Pu isotopes can be used to determine both the source reactor type and the initial fuel composition with good discrimination.

  17. Increase in tiagabine serum concentration with coadministration of gemfibrozil.

    Science.gov (United States)

    Burstein, Aaron H; Boudreau, Eilis A; Theodore, William H

    2009-02-01

    To report a case of possible acute tiagabine toxicity secondary to administration of gemfibrozil. A 39-year-old male was taking tiagabine 16 mg orally 3 times per day and carbamazepine 500 mg orally twice per day for complex partial seizures secondary to mesial temporal sclerosis. He was found to have type IV hypertriglyceridemia and was prescribed gemfibrozil. Because he reported severe confusion and altered consciousness shortly after a single 600-mg dose of gemfibrozil, he was admitted for controlled challenge with that drug. A single 300-mg dose of gemfibrozil resulted in lightheadedness and led to a 59% and 75% increase in total tiagabine serum concentrations at 2 and 5 hours, respectively, without significant change in baseline carbamazepine concentrations. This is the first report of an interaction between the widely used antihyperlipidemic drug gemfibrozil and tiagabine. Since tiagabine, which was originally developed as an antiepileptic medication, is now being used widely for a variety of other indications such as anxiety and depression, there is an increased risk for clinically significant interactions with gemfibrozil. Increased total and unbound tiagabine concentrations following a single 300-mg dose of gemfibrozil and reproduction of clinical symptoms with gemfibrozil rechallenge suggests the toxicity our patient experienced was due to a pharmacokinetic drug interaction. Use of the Horn Drug Interaction Probability Scale showed a probable interaction between gemfibrozil and tiagabine.

  18. Association between Serum Albumin Concentration and Ketosis Risk in Hospitalized Individuals with Type 2 Diabetes Mellitus.

    Science.gov (United States)

    Cheng, Po-Chung; Hsu, Shang-Ren; Cheng, Yun-Chung

    2016-01-01

    Objective. This study examined the association between serum albumin concentration and ketosis risk in hospitalized individuals with type 2 diabetes mellitus (T2DM). Methods. A retrospective cross-sectional study was conducted at a medical center in Taiwan. Inclusion criteria were endocrinology ward inpatients exceeding 21 years of age, with preexisting diagnosis of T2DM, and blood glucose above 13.9 millimoles per liter (mmol/L) at admission. Individuals without measurement of serum albumin, urine ketone, or hemoglobin A1C, or harboring active infection, myocardial infarction, cerebrovascular event, cirrhosis, malignancy, or overt proteinuria were excluded. Using serum albumin concentration below 3.0 grams per deciliter to define hypoalbuminemia, 151 hypoalbuminemic cases and 104 normoalbuminemic controls were enrolled. The presence of ketones in urine established ketosis. Results. The prevalence of ketonuria was 48% in hypoalbuminemic subjects compared to 30% in normoalbuminemic controls (odds ratio (OR): 2.15; 95% confidence interval (CI): 1.26-3.57; P = 0.004). Moreover, among the 156 subjects with serum beta-hydroxybutyrate measurement in addition to urine ketone, 33% of the hypoalbuminemic individuals had ketonemia exceeding 3 mmol/L compared to 19% of those with normoalbuminemia (OR: 2.12, 95% CI: 0.99-4.48, P = 0.051). Conclusions. Serum albumin concentration is inversely associated with ketosis risk in hospitalized individuals with T2DM.

  19. MFT homogeneity study at TNX: Final report on the low weight percent solids concentration

    International Nuclear Information System (INIS)

    Jenkins, W.J.

    1993-01-01

    A statistical design and analysis of both elemental analyses and weight percent solids analyses data was utilized to evaluate the MFT homogeneity at low heel levels and low agitator speed at both high and low solids feed concentrations. The homogeneity was also evaluated at both low and high agitator speed at the 6000+ gallons static level. The dynamic level portion of the test simulated feeding the Melter from the MFT to evaluate the uniformity of the solids slurry composition (Frit-PHA-Sludge) entering the melter from the MFT. This final report provides the results and conclusions from the second half of the study, the low weight percent solids concentration portion, as well as a comparison with the results from the first half of the study, the high weight percent solids portion

  20. Seafood Consumption and Blood Mercury Concentrations in Jamaican Children With and Without Autism Spectrum Disorders

    Science.gov (United States)

    Samms-Vaughan, Maureen; Loveland, Katherine A.; Ardjomand-Hessabi, Manouchehr; Chen, Zhongxue; Bressler, Jan; Shakespeare-Pellington, Sydonnie; Grove, Megan L.; Bloom, Kari; Pearson, Deborah A.; Lalor, Gerald C.; Boerwinkle, Eric

    2014-01-01

    Mercury is a toxic metal shown to have harmful effects on human health. Several studies have reported high blood mercury concentrations as a risk factor for autism spectrum disorders (ASDs), while other studies have reported no such association. The goal of this study was to investigate the association between blood mercury concentrations in children and ASDs. Moreover, we investigated the role of seafood consumption in relation to blood mercury concentrations in Jamaican children. Based on data for 65 sex- and age-matched pairs (2–8 years), we used a General Linear Model to test whether there is an association between blood mercury concentrations and ASDs. After controlling for the child’s frequency of seafood consumption, maternal age, and parental education, we did not find a significant difference (P = 0.61) between blood mercury concentrations and ASDs. However, in both cases and control groups, children who ate certain types of seafood (i.e., salt water fish, sardine, or mackerel fish) had significantly higher (all P mercury concentration which were about 3.5 times that of children living in the US or Canada. Our findings also indicate that Jamaican children with parents who both had education up to high school are at a higher risk of exposure to mercury compared to children with at least one parent who had education beyond high school. Based on our findings, we recommend additional education to Jamaican parents regarding potential hazards of elevated blood mercury concentrations, and its association with seafood consumption and type of seafood. PMID:22488160

  1. Reader practice in mammography screen reporting in Australia

    International Nuclear Information System (INIS)

    Reed, W.; Poulos, A.; Brennan, P.

    2009-01-01

    Full text: Reader variability is a problem in mammography image reporting and compromises the efficacy of screening programmes. The purpose of this exploratory study was to survey reader practice in reporting screening mammograms in Australia to identify aspects of practice that warrant further investigation. Mammography reporting practice and influences on concentration and attention were investigated by using an original questionnaire distributed to screen readers in Australia. A response rate of 71% (83 out of 117) was achieved. Demographic data indicated that the majority of readers were over 46 years of age (73%), have been reporting on screening mammograms for over 10 years (61%), take less than 1 min to report upon a screening mammogram examination (66%), report up to 200 examinations in a single session (83%) and take up to 2 h to report one session (61%). A majority report on more than 5000 examinations annually (66%); 93% of participants regard their search strategy as systematic, 87% agreed that their concentration can vary throughout a session, 64% agreed that the relatively low number of positives can lead to lapses in concentration and attention and almost all (94%) participants agreed that methods to maximise concentration should be explored. Participants identified a range of influences on concentration within their working environment including volume of images reported in one session, image types and aspects of the physical environment. This study has provided important evidence of the need to investigate adverse influences on concentration during mammography screen reporting

  2. Serum leptin concentrations in children with type 1 diabetes mellitus: relationship to body mass index, insulin dose, and glycemic control.

    Science.gov (United States)

    Soliman, Ashraf T; Omar, Magdi; Assem, Hala M; Nasr, Ibrahim S; Rizk, Mohamed M; El Matary, Wael; El Alaily, Rania K

    2002-03-01

    Although obesity is a frequent feature of type 2 diabetes mellitus (DM), many patients with type 1 DM are prone to high body mass index (BMI). We measured serum leptin concentrations in a cohort of children (n = 55) with type 1 diabetes mellitus (DM), as well as their anthropometric parameters including BMI, skin fold thickness at multiple sites, and midarm circumference. Glycemic control was assessed by blood glucose (BG) monitoring before meals, and measurement of glycated hemoglobin (HbA1c) and insulin dose/kg/d was recorded. Dietary evaluation and assessment of caloric intake (kg/d) was performed by an expert dietitian. In the newly diagnosed children (n = 10) before initiation of insulin therapy, circulating leptin concentration was significantly lower (1.1 +/- 0.8 ng/dL) versus 5 days after insulin therapy (1.45 +/- 0.7 ng/dL). The decreased leptin level appears to be related to insulinopenia in these patients. In 45 children with type 1 DM on conventional therapy (2 doses of insulin mixture (NPH and regular) subcutaneous (SC) before breakfast and dinner for more than 2 years), serum leptin concentration was significantly higher (2.15 +/- 1 ng/dL) compared with age-matched normal children (1.3 +/- 1 ng/dL). Diabetic children were further divided into 2 groups according to their HbA1c level: group 1 with HbA1C less than 7.5% (less than 2 SD above the mean for normal population) (n = 29) and group 2 with HbA1c greater than 7.5%. (greater than 2 SD above the mean for normal population) (n = 16). Patients with a higher HbA1c level (group 2) had a higher leptin concentration (2.3 +/- 0.8 ng/dL), higher BMI (17.8 +/- 1.7), and were receiving higher insulin dose/kg (0.92 +/- 0.2 U/kg/d) compared with group 1 (lower HbA1c) (1.78 +/- 0.8 ng/dL, 16.7 +/- 1.5, and 0.59 +/- 0.2 U/kg/d, respectively). Group 2 patients had a higher incidence of late morning hypoglycemia (9/29) versus group 1 patients (2/16). Analysis of dietary intake showed that patients with a higher Hb

  3. Spray-type drying unit for spent ion exchange resins, sludges and radioactive concentrates

    International Nuclear Information System (INIS)

    Raibaud, J.

    1986-01-01

    The process for drying radwaste in the liquid form or in aqueous suspension is a very attractive solution from the standpoint of volume reduction. Most of the existing drying facilities are not well adapted for drying the varieties of aqueous waste produced by the nuclear research centres and nuclear power plants, such as: - ion exchange resins, bead type or powdered resins, - centrifuge sludges, - settling sludges, - evaporator bottoms. Technicatome has selected the LEAFLASH process developed by Rhone Poulenc Recherches for drying the nuclear aqueous waste. This process has been well tried at full scale in a large number of industrial branches. The advantages of the process have been confirmed by the results obtained in operating a pilot facility. They include: - high flexibility in operation: - quick start-up and stoppage procedures, - adaptation to a wide spectrum of liquid waste without significant changes in the adjustment of the device. - compactness, - low power consumption, - complete drying of the waste for any initial concentration [fr

  4. Towards High-Performance Aqueous Sodium-Ion Batteries: Stabilizing the Solid/Liquid Interface for NASICON-Type Na2 VTi(PO4 )3 using Concentrated Electrolytes.

    Science.gov (United States)

    Zhang, Huang; Jeong, Sangsik; Qin, Bingsheng; Vieira Carvalho, Diogo; Buchholz, Daniel; Passerini, Stefano

    2018-02-22

    Aqueous Na-ion batteries may offer a solution to the cost and safety issues of high-energy batteries. However, substantial challenges remain in the development of electrode materials and electrolytes enabling high performance and long cycle life. Herein, we report the characterization of a symmetric Na-ion battery with a NASICON-type Na 2 VTi(PO 4 ) 3 electrode material in conventional aqueous and "water-in-salt" electrolytes. Extremely stable cycling performance for 1000 cycles at a high rate (20 C) is found with the highly concentrated aqueous electrolytes owing to the formation of a resistive but protective interphase between the electrode and electrolyte. These results provide important insight for the development of aqueous Na-ion batteries with stable long-term cycling performance for large-scale energy storage. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. The serum uric acid concentration is not causally linked to diabetic nephropathy in type 1 diabetes.

    Science.gov (United States)

    Ahola, Aila J; Sandholm, Niina; Forsblom, Carol; Harjutsalo, Valma; Dahlström, Emma; Groop, Per-Henrik

    2017-05-01

    Previous studies have shown a relationship between uric acid concentration and progression of renal disease. Here we studied causality between the serum uric acid concentration and progression of diabetic nephropathy in 3895 individuals with type 1 diabetes in the FinnDiane Study. The renal status was assessed with the urinary albumin excretion rate and estimated glomerular filtration rate (eGFR) at baseline and at the end of the follow-up. Based on previous genomewide association studies on serum uric acid concentration, 23 single nucleotide polymorphisms (SNPs) with good imputation quality were selected for the SNP score. This score was used to assess the causality between serum uric acid and renal complications using a Mendelian randomization approach. At baseline, the serum uric acid concentration was higher with worsening renal status. In multivariable Cox regression analyses, baseline serum uric acid concentration was not independently associated with progression of diabetic nephropathy over a mean follow-up of 7 years. However, over the same period, baseline serum uric acid was independently associated with the decline in eGFR. In the cross-sectional logistic regression analyses, the SNP score was associated with the serum uric acid concentration. Nevertheless, the Mendelian randomization showed no causality between uric acid and diabetic nephropathy, eGFR categories, or eGFR as a continuous variable. Thus, our results suggest that the serum uric acid concentration is not causally related to diabetic nephropathy but is a downstream marker of kidney damage. Copyright © 2016 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

  6. Correlation between total nitrite/nitrate concentrations and monoamine oxidase (types A and B) and semicarbazide-sensitive amine oxidase enzymatic activities in human mesenteric arteries from non-diabetic and type 2 diabetic patients

    Energy Technology Data Exchange (ETDEWEB)

    Nunes, S.F.; Figueiredo, I.V. [Laboratório de Farmacologia, Faculdade de Farmácia, Universidade de Coimbra, Coimbra (Portugal); Pereira, J.S. [Instituto Português de Oncologia de Coimbra, Coimbra (Portugal); Lopes, M.C.; Caramona, M.M. [Laboratório de Farmacologia, Faculdade de Farmácia, Universidade de Coimbra, Coimbra (Portugal)

    2011-11-25

    The aim of this study was to determine the correlation between total nitrite/nitrate concentrations (NOx) and the kinetic parameters of monoamine oxidase enzymes (MAO-A and MAO-B) and semicarbazide-sensitive amine oxidase (SSAO) in human mesenteric arteries. Arteries were from non-diabetic and type 2 diabetic patients with sigmoid or rectum carcinoma for whom surgery was the first option and who were not exposed to neo-adjuvant therapy. Segments of human inferior mesenteric arteries from non-diabetic (61.1 ± 8.9 years old, 7 males and 5 females, N = 12) and type 2 diabetic patients (65.8 ± 6.2 years old, 8 males and 4 females, N = 12) were used to determine NOx concentrations and the kinetic parameters of MAO-A, MAO-B and SSAO by the Griess reaction and by radiochemical assay, respectively. The NOx concentrations in arteries from diabetic patients did not differ significantly from those of the non-diabetic group (10.28 ± 4.61 vs 10.71 ± 4.32 nmol/mg protein, respectively). In the non-diabetic group, there was a positive correlation between NOx concentrations and MAO-B parameters: K{sub m} (r = 0.612, P = 0.034) and V{sub max} (r = 0.593, P = 0.042), and a negative correlation with the SSAO parameters: K{sub m} (r = -0.625, P = 0.029) and V{sub max} (r = -0.754, P = 0.005). However, in the diabetic group no correlation was found between NOx concentrations and the three kinetic parameters of the enzymes. These results suggest an important function of sympathetic nerves and vascular NOx concentrations in arteries of non-diabetic patients. Thus, these results confirm the importance of a balance between oxidants and antioxidants in the maintenance of vascular homeostasis to prevent oxidative stress.

  7. Heavy metals concentrations and risk assessment of roselle and jute mallow cultivated with three compost types

    Directory of Open Access Journals (Sweden)

    M. Abubakari

    2017-12-01

    Full Text Available Field experiments were conducted at the research field of the CSIR–SARI near Nyankpala in the Northern region of Ghana during the major growing seasons of 2014 and 2015. The objectives of the study were to determine the effect of three compost types i.e. Accra compost and recycling plant (ACARP compost; decentralised compost (DeCo and composted deep litter chicken manure (CDLCM on heavy metals concentrations in roselle (Hibiscus sabdariffa L. and jute mallow (Corchorus olitorius L. and the health risk of these vegetables to adults and children. The composts were each applied at the rate of 10 t/ha in a randomized complete block design in four replications. The concentrations of Cd and Pb in the leaves of roselle were 0.8 mg/kg and 5.0 mg/kg whiles in jute mallow, they were 0.7 mg/kg and 6.0 mg/kg, respectively. These concentrations were above the Maximum residue levels (MRLs of 0.2 mg/kg for Cd and 0.3 mg/kg for Pb in the standards of the European Commission and Codex Alimentarius Commission. The low soil pH might have facilitated the bioavailability of the heavy metals resulting in concentrations that could be harmful to consumers of these vegetables. There is, therefore, the need to amend the soil pH of the study area. An upward adjustment of the pH of the composts used can also help in reducing the bioavailability of heavy metals to roselle and jute mallow cultivated in soils with low pH.

  8. Metformin increases plasma ghrelin in Type 2 diabetes.

    Science.gov (United States)

    Doogue, Matthew P; Begg, Evan J; Moore, M Peter; Lunt, Helen; Pemberton, Chris J; Zhang, Mei

    2009-12-01

    * Metformin, unlike the other major antihyperglycaemic drugs, is not associated with weight gain. * Ghrelin is an appetite-stimulating hormone whose concentrations vary in relation to food, obesity and diabetes control. * Reports are conflicting about how metformin affects ghrelin concentrations, and this study was aimed at resolving this issue in patients with Type 2 diabetes. * In this study an increase in ghrelin concentrations was seen in response to metformin treatment in patients with Type 2 diabetes. * This effect was opposite to what might be expected if the effect of metformin on weight control was mediated via suppression of ghrelin. * It is likely that the ghrelin response was secondary to improved glycaemic control. * Meal time changes in appetite and satiety did not correlate with changes in ghrelin, which suggests ghrelin may not be important in meal initiation. Metformin treatment of Type 2 diabetes is not usually associated with weight gain, and may assist with weight reduction. Plasma ghrelin concentrations are inversely associated with obesity and food intake. Metformin might therefore affect ghrelin concentrations, although previous studies have shown variable results in this regard. The primary aim of this study was to determine the effect of metformin on plasma ghrelin, appetite and satiety in patients with Type 2 diabetes. Eighteen patients with Type 2 diabetes were studied before and after 6 weeks of metformin treatment, which was titrated to 1 g b.d. On the study days patients were fed standard meals of 390 kcal at 08.00 and 12.30 h, plasma samples were collected at 15- and 30-min intervals, and appetite and satiety were measured on visual analogue scales. Changes in the area under the concentration-time curves (AUCs) of plasma ghrelin, insulin, glucose, appetite and satiety were assessed and examined for correlations with metformin AUCs. Changes in fasting adiponectin and leptin were also measured. Treatment with metformin increased the

  9. The impact of production type and region on polychlorinated biphenyl (PCB), polychlorinated dibenzo-p-dioxin and dibenzofuran (PCDD/F) concentrations in Canadian chicken egg yolks.

    Science.gov (United States)

    Rawn, Dorothea F K; Sadler, Amy R; Quade, Sue C; Sun, Wing-Fung; Kosarac, Ivana; Hayward, Stephen; Ryan, J Jake

    2012-11-01

    Chicken eggs from five different production types (conventional, omega-3 enriched, free range, organic and free run) were collected, when available, from three regions (west, central and east) of Canada to determine persistent organic pollutant (POP) concentrations. Total polychlorinated biphenyl (PCB) concentrations (∑37 congeners) in yolks from the eggs ranged from 0.162 ng g(-1) lipid to 24.8 ng g(-1) lipid (median 1.25 ng g(-1) lipid) while the concentration of the sum of the 6 indicator PCBs ranged from 0.100 ng g(-1) lipid to 9.33 ng g(-1) lipid (median 0.495 ng g(-1) lipid). Total polychlorinated dibenzo-p-dioxin/dibenzofuran (PCDD/F) concentrations ranged from 2.37 pg g(-1) lipid to 382 pg g(-1) lipid (median 9.53 pg g(-1) lipid). The 2005 WHO toxic equivalency (TEQ) ranged from 0.089 pg TEQ(PCDD/F+dioxin-like[DL]-PCB) g(-1) lipid to 12.8 pg TEQ(PCDD/F+DL-PCB) g(-1) lipid (median 0.342 pg TEQ(PCDD/F+DL-PCB) g(-1) lipid). PCB and PCDD/F concentrations were significantly different (pcollection. In contrast to observations in Europe, PCB and PCDD/F concentrations in Canadian egg yolks were not impacted solely by the production type (e.g., conventional, free range, organic, etc.) used to maintain the laying chickens. Additionally, only one Canadian free range yolk from western Canada (12.8 pg TEQ(PCDD/F+DL-PCB) g(-1) lipid) exceeded the European toxic equivalent concentration limits for eggs (5 pg TEQ(PCDD/F+DL-PCB) g(-1) lipid). This differs from observations in Europe where free range/home produced eggs frequently have higher POP concentrations than eggs from other production types. Median PCB dietary intake estimates based on consumption of eggs were less than 10 ng d(-1) while median PCDD/F intakes were less than 45 pg d(-1). Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  10. MCB-2 concentration meter for boric acid

    International Nuclear Information System (INIS)

    Lisecki, W.

    1978-01-01

    The principles are explained of the thermal neutron absorption method for monitoring boric acid concentration in the WWER type reactor coolant. The design principles and the characteristics of four variants are described of the MSB-2 type boric acid concentration monitor developed by IBJ. (B.S.)

  11. Effect of i.p. insulin administration onIGF1 and IGFBP1 in type1 diabetes

    NARCIS (Netherlands)

    van Dijk, P R; Logtenberg, S J J; Groenier, K H; Kleefstra, N; Bilo, H J G; Arnqvist, H J

    2014-01-01

    In type 1 diabetes mellitus (T1DM), low concentrations of IGF1 and high concentrations of IGF-binding protein 1 (IGFBP1) have been reported. It has been suggested that these abnormalities in the GH-IGF1 axis are due to low insulin concentrations in the portal vein. We hypothesized that the i.p.

  12. Performance Study of a Cylindrical Parabolic Concentrating Solar Water Heater with Nail Type Twisted Tape Inserts in the Copper Absorber Tube

    Directory of Open Access Journals (Sweden)

    Amit K. Bhakta

    2018-01-01

    Full Text Available This paper reports the overall thermal performance of a cylindrical parabolic concentrating solar water heater (CPCSWH with inserting nail type twisted tape (NTT in the copper absorber tube for the nail twist pitch ratios, 4.787, 6.914 and 9.042, respectively. The experiments are conducted for a constant volumetric water flow rate and during the time period 9:00 a.m. to 15:00 p.m. The useful heat gain, hourly solar energy collected and hourly solar energy stored in this solar water heater were found to be higher for the nail twist pitch ratio 4.787. The above said parameters were found to be at a peak at noon and observed to follow the path of variation of solar intensity. At the start of the experiment, the value of charging efficiency was observed to be maximum, whereas the maximum values of instantaneous efficiency and overall thermal efficiency were observed at noon. The key finding is that the nail twist pitch ratio enhances the overall thermal performance of the CPCSWH.

  13. Tension - Type - Headache treated by Positional Release Therapy: a case report.

    Science.gov (United States)

    Mohamadi, Marzieh; Ghanbari, Ali; Rahimi Jaberi, Abbas

    2012-10-01

    Tension Type Headache (T.T.H) is the most prevalent headache. Myofascial abnormalities & trigger points are important in this type of headache which can be managed by Positional Release Therapy (PRT). This is a report of a 47 years old female patient with Tension Type Headache treated by Positional Release Therapy for her trigger points. She had a constant dull headache, which continued all the day for 9 months. A physiotherapist evaluated the patient and found active trigger points in her cervical muscles. Then, she received Positional Release Therapy for her trigger points. After 3 treatment sessions, the patient's headache stopped completely. During the 8 months following the treatment she was without pain, and did not use any medication. Positional Release Therapy was effective in treating Tension Type Headache. This suggests that PRT could be an alternative treatment to medication in patients with T.T.H if the effectiveness of that can be confirmed by further studies. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. A Qualitative Study of Vulnerable Patient Views of Type 2 Diabetes Consumer Reports.

    Science.gov (United States)

    Longo, Daniel R; Crabtree, Benjamin F; Pellerano, Maria B; Howard, Jenna; Saver, Barry; Hannan, Edward L; Lee, Justin; Lundberg, Michael T; Sabo, Roy

    2016-06-01

    The Patient Protection and Affordable Care Act (ACA) mandates the release of publicly available consumer reports to highlight differences in quality of care and reduce healthcare disparities. However, little is known about patient perceptions of the value of such reports. This study aims to identify whether vulnerable populations with type 2 diabetes perceive consumer reports as helpful in making decisions about diabetes care. We conducted a brief demographic survey and qualitative study of 18 focus groups: six each of African American, Hispanic, and non-Hispanic White consumers diagnosed with type 2 diabetes (n = 92). We analysed focus group transcripts to identify recurring themes, which were summarized and compared across population groups. Participants expressed minimal interest in currently available consumer reports. They instead listed personal referrals and interpersonal interactions among the most important factors when choosing a physician. Further, in place of information to aid in physician selection, participants articulated strong desires for more basic, straightforward disease-specific information that would promote diabetes self-management. This study's results call into question the value of consumer reports as defined by the ACA. Participants reported little interest in comparative provider performance data. Instead, they were more interested in information to assist in diabetes self-management. This suggests that consumer reports may not be as important a tool to improve outcomes and reduce health disparities as policy makers imagine them to be.

  15. Croatian banking sector research: relationship between ownership structure, concentration, owners’ type and bank performance

    Directory of Open Access Journals (Sweden)

    Igor Tomičić

    2012-12-01

    Full Text Available Banks are important financial intermediaries of any national economy, and corporate governance has an important role in banking sector; especially due to processes of the globalization and the internationalization, and also because of the sensitivity of the activities between the interest groups. The objective of this paper is to examine the relationship between ownership structure, concentration, owners’ type and bank performance. The authors made a research of banks' ownership structure using publicly available data. Using statistical tools authors discovered relationships between bank ownership structure and bank performance indicators (average asset, total asset, average equity, profit (loss before taxes, profit (loss after taxes, ROAA, ROAE. Further they discuss the relationships between ownership structure and a number of consequences for the bank performance. The authors discovered significant correlation between bank ownership structure and performance indicators variables that are described in the paper.

  16. Rapid and efficient treatment of wastewater with high-concentration heavy metals using a new type of hydrogel-based adsorption process.

    Science.gov (United States)

    Zhou, Guiyin; Liu, Chengbin; Chu, Lin; Tang, Yanhong; Luo, Shenglian

    2016-11-01

    In this study, a new type of double-network hydrogel sorbent was developed to remove heavy metals in wastewater. The amino-functionalized Starch/PAA hydrogel (NH2-Starch/PAA) could be conducted in a wide pH and the adsorption process could rapidly achieve the equilibrium. The adsorption capacity got to 256.4mg/g for Cd(II). Resultantly, even though Cd(II) concentration was as high as 180mg/L, the Cd(II) could be entirely removed using 1g/L sorbent. Furthermore, the desirable mechanical durability of the adsorbent allowed easy separation and reusability. In the fixed-bed column experiments, the treatment volume of the effluent with a high Cd(II) concentration of 200mg/L reached 2400BV (27.1L) after eight times cycle. The NH2-Starch/PAA overcame the deficiency of conventional sorbents that could not effectively treat the wastewater with relatively high metal concentrations. This work provides a new insight into omnidirectional enhancement of sorbents for removing high-concentration heavy metals in wastewater. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Type 2 diabetes mellitus is associated with differential effects on plasma cholesteryl ester transfer protein and phospholipid transfer protein activities and concentrations

    NARCIS (Netherlands)

    Dullaart, RPF; De Vries, R; Scheek, L; Borggreve, SE; Van Gent, T; Dallinga-Thie, GM; Ito, M; Nagano, M; Sluiter, WJ; Hattori, H; Van Tol, A

    Background: Human plasma contains two lipid transfer proteins, cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP), which are crucial in reverse cholesterol transport. Methods: Plasma CETP and PLTP activity levels and concentrations in 16 type 2 diabetic patients and

  18. Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes

    DEFF Research Database (Denmark)

    Højlund, K.; Frystyk, J.; Levin, K.

    2006-01-01

    AIMS/HYPOTHESIS: Circulating levels of adiponectin are negatively associated with multiple indices of insulin resistance, and the concentration is reduced in humans with insulin resistance and type 2 diabetes. However, the mechanisms by which adiponectin improves insulin sensitivity remain unclear...... (ten lean, 21 obese and 20 with type 2 diabetes). RESULTS: Plasma adiponectin was significantly reduced in type 2 diabetic compared with obese and lean subjects. In lean and obese subjects, insulin significantly reduced plasma adiponectin, but this response was blunted in patients with type 2 diabetes...... by improving the capacity to switch from lipid to glucose oxidation and to store glucose as glycogen in response to insulin, and that low adiponectin may contribute to impaired insulin activation of GS in skeletal muscle of patients with type 2 diabetes....

  19. Final characterization report for the non-process areas of the 233-S Plutonium Concentration Facility

    International Nuclear Information System (INIS)

    Encke, D.B.; Harris, R.A.

    1997-04-01

    This report addresses the 233-S Plutonium Concentration Facility characterization survey data collected from January 21, 1997 through February 3, 1997. The characterization activities evaluated the radiological status and identified the hazardous materials locations. The scope of this report is limited to the nonprocess areas in the facility, which include the special work permit (SWP) change room, toilet, equipment room, electrical cubicle, control room, and pipe gallery. A portion of the roof (excluding the roof over the process hood and viewing room) was also included. Information in this report will be used to identify waste streams, provide specific chemical and radiological data to aid in planning decontamination and demolition activities, and allow proper disposal of the demolition debris, as required by the Comprehensive Environmental Response, Compensation, and Liability Act of 1980

  20. Terrestrial photovoltaic power systems with sunlight concentration. Annual progress report, January 1, 1975--December 31, 1975

    Energy Technology Data Exchange (ETDEWEB)

    Backus, C.E.

    1976-01-31

    This annual report is for the second year of a program to investigate the characteristics of the components and the total system using sunlight concentrated onto solar cells. The second year was primarily to experimentally investigate the conclusions of the first year of analytical studies. Cells have been fabricated that are designed for different intensities. Typically the efficiency of a cell will increase from its 11 percent at AM1 peak to efficiency at the designed concentration level and return to its initial efficiency at about 3 times its designed concentration level. The developed cells have been tested under high intensity simulators and in concentrated sunlight and have shown to have the predicted response. The experimental testing of passive cooling limitations for cooling cells with just finned arrangements in the back of the cell has been completed in the controlled environment of a wind tunnel. These experiments have confirmed the heat transfer coefficients that had been used in the analytical studies. Testing was done to collect heat transfer coefficients for actual wind conditions and these data show good agreement with the controlled wind tunnel data. Four photovoltaic/concentrator system experiments have been started with CR of about 3, 10, 25, and 100. System analysis has indicated that photovoltaic concentration systems may be attractive in low solar irradiation areas such as Cleveland.

  1. Studies of post-elution concentration of {sup 99m}-Tc eluted from a gel type chromatographic generator

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Katia N.; Osso Junior, Joao Alberto [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mail: norisuzuki6@yahoo.com.br; jaosso@ipen.br

    2007-07-01

    The radiopharmaceuticals most used in Diagnostic Nuclear Medicine are those labeled with the metastable technetium ({sup 99m}Tc) due to its ideal physical properties of decay (t{sub 1/2} 6.01 h, E{gamma} 140 keV), low cost and availability facilitated through the commercial generator {sup 99}Mo /{sup 99m}Tc. This radionuclide is formed by the {beta}{sup -} decay of {sup 99}Mo adsorbed on an alumina column of the generator and collected in the form of sodium pertechnetate (Na{sup 99m}TcO{sub 4}) by elution with saline solution (0.9%). The Radiopharmacy Center (CR) of the IPEN-CNEN/SP developed a gel type chromatographic generator of MoZr with {sup 99}Mo produced by {sup 98}Mo(n, {gamma}){sup 99}Mo reaction that occurs in IEA-R1 Nuclear Reactor. The gel is composed of zirconium molybdate with elution volume of 12 ml with an activity of 11100 MBq (300 mCi) producing a radioactive concentration of 925 MBq (34 mCi) / ml. The fission generator gives a higher radioactive concentration around 1850 MBq (69 mCi) / ml. The aim of this work is to study a system of post-elution concentration using ion exchange cartridges in tandem (cation - anion) for the attainment of a high enough radioactive concentration to meet the demand of market, with a proved quality. This system of concentration will be made based in the technique of solid phase extraction (SPE) using commercial cartridges of extraction, which contains the solid phase and eluent saline solution (0.9%). As the eluent results of this system used in the gel generator of MoZr will be compared with the fission generator currently produced by IPEN-CNEN/SP. (author)

  2. Acute hyperinsulinemia is followed by increased serum concentrations of fibroblast growth factor 23 in type 2 diabetes patients

    DEFF Research Database (Denmark)

    Winther, Kristian; Nybo, Mads; Vind, Birgitte

    2012-01-01

    Background. Phosphate homeostasis is connected to glucose metabolism and is influenced by insulin, but the role of fibroblast growth factor 23 (FGF23) is unknown in this relation. Therefore, the levels of FGF23 and phosphate were investigated during a euglycemic-hyperinsulinemic clamp in healthy...... and type 2 diabetic individuals. Methods. The study population consisted of ten type 2 diabetic patients, ten weight-matched glucose-tolerant obese subjects, and ten healthy lean subjects. All subjects underwent a 4-h euglycemic-hyperinsulinemic clamp using physiological hyperinsulinemia (40 mU/min per m(2...... the groups. Conclusions. Physiological hyperinsulinemia is under euglycemic conditions followed by a significant increase in serum FGF23 concentrations in diabetic individuals, which correlated with change in insulin level. The interplay between insulin effects and FGF23 may be important...

  3. Impact of poor glycemic control of type 2 diabetes mellitus on serum prostate-specific antigen concentrations in men.

    Science.gov (United States)

    Atalay, Hasan Anıl; Akarsu, Murat; Canat, Lutfi; Ülker, Volkan; Alkan, İlter; Ozkuvancı, Unsal

    2017-09-01

    To evaluate the impact of poor glycemic control of type 2 diabetes mellitus (T2DM) on serum prostate-specific antigen (PSA) concentrations in men. We performed a prospective analysis of 215 consecutive patients affected by erectile dysfunction (ED). ED was evaluated using the IIEF-5 questionnaire and the poor glycemic control (PGC) of T2DM was assessed according to the HbA1c criteria (International Diabetes Federation). Patients were divided into PGC group (HbA1c ≥ 7%) and control group (CG) (HbA1c men ranging from 44 to 81 years of age, lower PSA concentrations were observed in men with PGC (PGC mean PSA: 0.9 ng/dl, CG mean PSA: 2.1 ng/dl, p men with PGC compared with men with CG (PGC mean prostate volume: 26 ml, CG prostate volume: 43 ml, p strong negative correlation was found between serum HbA1c levels and serum PSA (p men with PGC. We also found at the multivariate logistic regression model that PSA, prostate volume and peak systolic velocity were independent predictors of PGC. Our results suggest that there is significant impact of PGC on serum PSA levels in T2DM. Poor glycemic control of type 2 diabetes was associated with lower serum PSA levels and smaller prostate volumes.

  4. Commercial Application of a Photovoltaic Concentrator system. Phase I. Final report, 1 June 1978-28 February 1979

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, D.J.; Anderson, E.R.; Bardwell, K.M.

    1980-04-01

    This report documents the design and analysis of the BDM CAPVC (Commercial Application of a Photovoltaic Concentrator) system. The preliminary design, prototype test and evaluation, system analysis, and final design of a large-scale concentrating photovoltaic system are described. The application is on an attractive new office building which represents a large potential market. The photovoltaic concentrating array is a roof-mounted, single-axis linear parabolic trough, using single crystalline silicon photovoltaic cells. A total of 6720 square feet of aperture is focussed on 13,944 PV cells. The photovoltaic system operates in parallel with the local utility in an augmentary loadsharing operating mode. The array is actively cooled and the thermal energy utilized for building heat during winter months. (WHK)

  5. Type IIA2 urethral duplication: report of an unusual case | Gupta ...

    African Journals Online (AJOL)

    This report describes a rare case of type IIA2 sagittal urethral duplication. The presentation, investigation, and management of this rare anomaly are briefly discussed. A 3½-year-old boy presented with urinary obstruction and recurrent urinary tract infection due to a stenosed dorsal urethra and segmental stenosis of the ...

  6. Vitamin D - Dependent Rickets, Type II Case Report

    Science.gov (United States)

    Azemi, Mehmedali; Berisha, Majlinda; Ismaili-Jaha, Vlora; Kolgeci, Selim; Hoxha, Rina; Grajçevci-Uka, Violeta; Hoxha-Kamberi, Teuta

    2014-01-01

    Aim: The aim of this work the report of one case with vitamin D-dependent rickets, type II. Methods: Diagnosis has been established based on anamnesis, physical examination, laboratory findings and radiological examination. Results: A female child (age 25 months) has been hospitalized due to bone deformity, bone pain, alopecia and walking difficulties. The laboratory findings have revealed that the calcium values was low (1.20 mmol/L), phosphates in the reference value (1.30 mmol/L) the alkaline phosphatase value was quite high (852 IU/L), high value of parathyroid hormone (9.21 pmol/L), normal value of 25- hydroxyvitamin D, whereas the values of 1,25-dihydroxyvitamin D was high (185 μmol/L). Radiographic changes were evident and typical in the distal metaphysis of radius and ulna as well as in the bones of lower limbs (distal metaphysis of femur and proximal metaphysis of tibia and fibula). After treatment with calcium and calcitriol, the above mentioned clinical manifestations, laboratory test values and the radiographic changes in bones withdrew. Conclusions: Vitamin D-dependent rickets, type II is a rare genetic recessive disease, and its treatment includes a constant use of calcium and calcitriol. PMID:24757409

  7. Filter Membrane Effects on Water-Extractable Phosphorus Concentrations from Soil.

    Science.gov (United States)

    Norby, Jessica; Strawn, Daniel; Brooks, Erin

    2018-03-01

    To accurately assess P concentrations in soil extracts, standard laboratory practices for monitoring P concentrations are needed. Water-extractable P is a common analytical test to determine P availability for leaching from soils, and it is used to determine best management practices. Most P analytical tests require filtration through a filter membrane with 0.45-μm pore size to distinguish between particulate and dissolved P species. However, filter membrane type is rarely specified in method protocols, and many different types of membranes are available. In this study, three common filter membrane materials (polyether sulfone, nylon, and nitrocellulose), all with 0.45-μm pore sizes, were tested for analytical differences in total P concentrations and dissolved reactive P (DRP) concentrations in water extracts from six soils sampled from two regions. Three of the extracts from the six soil samples had different total P concentrations for all three membrane types. The other three soil extracts had significantly different total P results from at least one filter membrane type. Total P concentration differences were as great as 35%. The DRP concentrations in the extracts were dependent on filter type in five of the six soil types. Results from this research show that filter membrane type is an important parameter that affects concentrations of total P and DRP from soil extracts. Thus, membrane type should be specified in soil extraction protocols. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  8. Effects of forage type, forage to concentrate ratio, and crushed linseed supplementation on milk fatty acid profile in lactating dairy cows

    NARCIS (Netherlands)

    Sterk, A.R.; Johansson, B.E.O.; Taweel, H.Z.H.; Murphy, M.; Vuuren, van A.M.; Hendriks, W.H.; Dijkstra, J.

    2011-01-01

    The effects of an increasing proportion of crushed linseed (CL) in combination with varying forage type (grass or corn silage) and forage to concentrate ratio (F:C), and their interactions on milk fatty acid (FA) profile of high-producing dairy cows was studied using a 3-factor Box-Behnken design.

  9. Pollutant concentrations in road runoff: Southeast Queensland case study

    Energy Technology Data Exchange (ETDEWEB)

    Drapper, D.; Tomlinson, R.; Williams, P.

    2000-04-01

    This paper discusses the results of research into the pollutants in runoff from road pavement surfaces following natural rainfall events. Road runoff water quality was monitored at 21 sites centering around Brisbane, in southeast Queensland, Australia. The sites were selected according to traffic volumes, surrounding land use, pavement surface type, ease of access, and commercial vehicle percentage. Bridge sites were chosen for convenience of sample collection and minimized infrastructure modification. First flush grab samplers were permanently installed at each site to collect the first 20 L of runoff from one of the bridge drainage scuppers. The runoff samples were tested for a number of heavy metals, hydrocarbons, pesticides, and other physical characteristics. The observed results fall within the ranges of concentrations reported internationally and nationally but do not typically follow the 30,000 average annual daily traffic results reported in the United States. Traffic volumes have not been found to be the best indicator of road runoff pollutant concentrations. Interevent duration has been found to be a statistically significant factor for pollutant concentrations. Sites incorporating exit lanes have recorded higher concentrations of acid-extractable copper and zinc, tending to support the hypothesis that brake pad and tire wear caused by rapid deceleration contributes to the concentrations of these metals in road runoff. Laser particle sizing has shown that a significant proportion of the sediment found in the runoff is <100 {micro}m. However, these particulates do settle in water within 24 h, under laboratory conditions. This may be due to the presence of heavy metals.

  10. Inhibition of intergranular stress corrosion cracking of sensitized type 304 stainless steel. Annual report

    International Nuclear Information System (INIS)

    Brown, B.F.

    1977-01-01

    The effectiveness of various inhibitors in mitigating stress corrosion cracking of stainless steel in hot aqueous environment was evaluated. The inhibitors studied were of three types: poly-oxy-anions, organic competitive absorbers, and simple cations; the corrosive medium was 4M NaCl acidified with H 2 SO 4 to ph of about 2.3. The following conclusions were reached: pH does not affect cracking kinetics in a sensitive way; cracking time is highly dependent on chloride concentrations; poly-oxy-anions do not perform well; organics offer some possibilities as inhibitors; cationic additives can have effects varying from trivial to total suppression of cracking--behavior is both cation and concentration dependent. 2 figures, 5 tables

  11. Varying hemin concentrations affect Porphyromonas gingivalis strains differently.

    Science.gov (United States)

    Ohya, Manabu; Cueno, Marni E; Tamura, Muneaki; Ochiai, Kuniyasu

    2016-05-01

    Porphyromonas gingivalis requires heme to grow, however, heme availability and concentration in the periodontal pockets vary. Fluctuations in heme concentration may affect each P. gingivalis strain differently, however, this was never fully demonstrated. Here, we elucidated the effects of varying hemin concentrations in representative P. gingivalis strains. Throughout this study, representative P. gingivalis strains [FDC381 (type I), MPWIb-01 (type Ib), TDC60 (type II), ATCC49417 (type III), W83 (type IV), and HNA99 (type V)] were used and grown for 24 h in growth media under varying hemin concentrations (5 × , 1 × , 0.5 × , 0.1 × ). Samples were lysed and protein standardized. Arg-gingipain (Rgp), H2O2, and superoxide dismutase (SOD) levels were subsequently measured. We focused our study on 24 h-grown strains which excluded MPWIb-01 and HNA99. Rgp activity among the 4 remaining strains varied with Rgp peaking at: 1 × for FDC381, 5 × for TDC60, 0.5 × for ATCC49417, 5 × and 0.5 × for W83. With regards to H2O2 and SOD amounts: FDC381 had similar H2O2 amounts in all hemin concentrations while SOD levels varied; TDC60 had the lowest H2O2 amount at 1 × while SOD levels became higher in relation to hemin concentration; ATCC49417 also had similar H2O2 amounts in all hemin concentrations while SOD levels were higher at 1 × and 0.5 × ; and W83 had statistically similar H2O2 and SOD amounts regardless of hemin concentration. Our results show that variations in hemin concentration affect each P. gingivalis strain differently. Published by Elsevier Ltd.

  12. Advances in study of perpes simplex virus type 1-thymidine kinase reporter gene imaging

    International Nuclear Information System (INIS)

    Liu Ying; Lan Xiaoli; Zhang Yongxue

    2007-01-01

    Radionuclide reporter gene imaging is an effect way to provide qualitative and quantitative information for gene therapy. There are three systems of reporter gene including kinase reporter gene. perpes simplex virus type 1-thymidine kinase (HSV1-tk) has perfect physical and chemical characteristic which is suit for imaging as reporter gene. It has been widely investigated and intensively researched. Two substrates of HSV1-tk are purine nucleosite derivant and acyclovir derivant, which can also be used as reporter probes of HSV1-tk. (authors)

  13. Studies of techniques for the post-elution concentration of 99mTc obtained from gel type 99Mo/99mTc generators

    International Nuclear Information System (INIS)

    Suzuki, Katia Noriko

    2009-01-01

    On average 80% of the radiopharmaceuticals used in Nuclear Medicine are labeled with 99 mTc due to its physical properties and easy attainment through of 99 Mo/ 99 mTc generators. The Directory of Radiopharmacy (DIRF) of IPEN-CNEN/SP developed a gel type chromatographic generator of MoZr with 99 Mo produced by 98 Mo(n,γ) 99 Mo reaction that occurs at the IEA-R1 Nuclear Reactor. The gel is composed of zirconium molybdate with elution volume of 12 mL with an activity of 11100 MBq (300 mCi) producing a radioactive concentration of 925 MBq (25 mCi)/mL. The fission generator gives a higher radioactive concentration around 1850 MBq (50 mCi)/mL. The aim of this work is to study a system of post-elution concentration of 99 mTc for the attainment of a high enough radioactive concentration to meet the demands of the market, with a proved quality. Two types of systems of post-elution concentration were developed: the single and the tandem. The most appropriate system for the gel generator of 99 Mo/ 99 mTc, being at the same time sterile and vacuum automated, was the tandem system using Dionex 2.5 cc/QMA cartridges. The gel generator is eluted with 10 mL of solution of 0.1% NaCl and the pertechnetate anion is retained in the QMA cartridge and further eluted with 4 mL of saline. The process takes no more than 30 minutes. The elution efficiency of the system of concentration was 90 %. At the beginning of 2009 a global crisis in the supply of 99 Mo took place making it necessary the development of alternative technologies for the production of 99 Mo/ 99 mTc generators using fission produced 99 Mo and the development of an appropriate method to extend the useful life of this generator. The results of this study showed that the same system developed for the post- concentration of the gel generator can be employed for the fission generator, using the tandem system, giving a concentration factor of 3 for the elution of 99 mTc. (author)

  14. A little "dab" will do ya' in: a case report of neuro-and cardiotoxicity following use of cannabis concentrates.

    Science.gov (United States)

    Rickner, Shannon S; Cao, Dazhe; Kleinschmidt, Kurt; Fleming, Steven

    2017-11-01

    The use of marijuana and cannabis concentrates is increasing, especially following decriminalization in several states. Psychosis and cardiotoxicity have been reported following cannabis use; however, myocardial injury from "dabbing" has not yet been reported. We report a case of hyperthermia, tachycardia, hypertension, severe agitation, neuro-, and cardiotoxicity following the use of "dabs" where there is concomitant confirmatory biological and sample testing. A 17-year-old athletic man developed agitation requiring sedation and intubation for safety, with peak systolic blood pressures in the 190s and hyperthermia (to 102 °F). He developed elevated serum troponins with persistent tachycardia despite sedation and no clear non-intoxicant etiology. It was discovered that the patient had recently been "dabbing"; an exhaustive search of his home found a sample of the "dabs" which was analyzed along with a comprehensive urine drug screen by tandem liquid mass spectroscopy (t-LCMS) for confirmation. Tetrahydrocannabinol (THC) has been increasingly associated with agitation and cardiotoxicity, while cannabidiol (CBD) has been associated with neuroprotective, inhibitory states. We propose that increasing concentrations of THC as well as THC:CBD ratios seen in cannabis concentrates such as "dabs" may cause agitation and end-organ damage through sympathomimetic and serotonergic pathways.

  15. Plexiform Schwannoma of the Stomach in Neurofibromatosis Type 2: A Case Report

    International Nuclear Information System (INIS)

    Kim, Hyun Jung; Yeom, Dong Heon; Cho, Hyun Sun; Cho, Woo Ho

    2012-01-01

    Plexiform schwannoma is a relatively rare benign subepithelial tumor arising from the peripheral nerve sheath, and associated with Neurofibromatosis type 2 (NF2). There are a few reports of plexiform schwannomas arising from the gastrointestinal tract, and to our knowledge, there is no report of it arising from the stomach in a patient with NF2. Here we present the first case of a plexiform schwannoma of the stomach in an NF2 patient a submucosal tumor on radiologic finding.

  16. The residual C concentration control for low temperature growth p-type GaN

    International Nuclear Information System (INIS)

    Liu Shuang-Tao; Zhao De-Gang; Yang Jing; Jiang De-Sheng; Liang Feng; Chen Ping; Zhu Jian-Jun; Liu Zong-Shun; Li Xiang; Liu Wei; Xing Yao; Zhang Li-Qun

    2017-01-01

    In this work, the influence of C concentration to the performance of low temperature growth p-GaN is studied. Through analyses, we have confirmed that the C impurity has a compensation effect to p-GaN. At the same time we have found that several growth and annealing parameters have influences on the residual C concentration: (i) the C concentration decreases with the increase of growth pressure; (ii) we have found there exists a Ga memory effect when changing the Cp 2 Mg flow which will lead the growth rate and C concentration increase along the increase of Cp 2 Mg flow; (iii) annealing outside of metal–organic chemical vapor deposition (MOCVD) could decrease the C concentration while in situ annealing in MOCVD has an immobilization role to C concentration. (paper)

  17. Predictors of Indoor Radon Concentrations in Pennsylvania, 1989–2013

    Science.gov (United States)

    Casey, Joan A.; Ogburn, Elizabeth L.; Rasmussen, Sara G.; Irving, Jennifer K.; Pollak, Jonathan; Locke, Paul A.

    2015-01-01

    Background Radon is the second-leading cause of lung cancer worldwide. Most indoor exposure occurs by diffusion of soil gas. Radon is also found in well water, natural gas, and ambient air. Pennsylvania has high indoor radon concentrations; buildings are often tested during real estate transactions, with results reported to the Department of Environmental Protection (PADEP). Objectives We evaluated predictors of indoor radon concentrations. Methods Using first-floor and basement indoor radon results reported to the PADEP between 1987 and 2013, we evaluated associations of radon concentrations (natural log transformed) with geology, water source, building characteristics, season, weather, community socioeconomic status, community type, and unconventional natural gas development measures based on drilled and producing wells. Results Primary analysis included 866,735 first measurements by building, with the large majority from homes. The geologic rock layer on which the building sat was strongly associated with radon concentration (e.g., Axemann Formation, median = 365 Bq/m3, IQR = 167–679 vs. Stockton Formation, median = 93 Bq/m3, IQR = 52–178). In adjusted analysis, buildings using well water had 21% higher concentrations (β = 0.191, 95% CI: 0.184, 0.198). Buildings in cities (vs. townships) had lower concentrations (β = –0.323, 95% CI: –0.333, –0.314). When we included multiple tests per building, concentrations declined with repeated measurements over time. Between 2005 and 2013, 7,469 unconventional wells were drilled in Pennsylvania. Basement radon concentrations fluctuated between 1987 and 2003, but began an upward trend from 2004 to 2012 in all county categories (p Pennsylvania, 1989–2013. Environ Health Perspect 123:1130–1137; http://dx.doi.org/10.1289/ehp.1409014 PMID:25856050

  18. Cost effective manufacturing of the SEA 10X concentrator array. Final subcontract report, 9 January 1991--April 1991

    Energy Technology Data Exchange (ETDEWEB)

    Kaminar, N.; McEntee, J.; Curchod, D. [Solar Engineering Applications Corp., San Jose, CA (US)

    1991-11-01

    This report describes a low-cost, mass-producible 10X concentrator system that has been claimed to produce electricity at $0.04/kWh. It details changes in manufacturing techniques that could produce a concentrator system at a selling price of $0.71/W. (A simple design and a minimum number of parts and manufacturing steps reduced production costs.) Present production techniques, changes to improve these techniques, impediments to changes, and solutions to the impediments are described. This 10X concentrator system uses available components and manufacturing processes and one-sun solar cells in conjunction with inexpensive plastic lenses to generate about eight times the amount of electricity normally produced by these cells.

  19. Desmoid type fibromatosis in the facet joint of lumbar spine: Case report and review of literature

    Energy Technology Data Exchange (ETDEWEB)

    Kim, So Jung; Ha, Doo Hoe; Lee, Sang Min; Kang, Hae Youn [CHA Bundang Medical Center, CHA University, Seongnam (Korea, Republic of)

    2013-10-15

    Desmoid type fibromatosis is a benign fibroblastic tumor arising from the fascia or musculoaponeurosis. It may occur in various locations, but most commonly in the shoulder girdle and neck; to our knowledge, there has been no reported case originating from a facet joint of the spine. We report CT and MR imaging findings of a desmoid type fibromatosis, involving the facet joint of the L3-4 spine with bone involvement.

  20. Normal Morning Melanin-Concentrating Hormone Levels and No Association with Rapid Eye Movement or Non-Rapid Eye Movement Sleep Parameters in Narcolepsy Type 1 and Type 2

    DEFF Research Database (Denmark)

    Schrölkamp, Maren; Jennum, Poul J; Gammeltoft, Steen

    2017-01-01

    in rapid eye movement (REM) and non-rapid eye movement (NREM) sleep regulation. Hypocretin neurons reciprocally interact with MCH neurons. We hypothesized that altered MCH secretion contributes to the symptoms and sleep abnormalities of narcolepsy and that this is reflected in morning cerebrospinal fluid...... MCH levels. CONCLUSIONS: Our study shows that MCH levels in CSF collected in the morning are normal in narcolepsy and not associated with the clinical symptoms, REM sleep abnormalities, nor number of muscle movements during REM or NREM sleep of the patients. We conclude that morning lumbar CSF MCH......STUDY OBJECTIVES: Other than hypocretin-1 (HCRT-1) deficiency in narcolepsy type 1 (NT1), the neurochemical imbalance of NT1 and narcolepsy type 2 (NT2) with normal HCRT-1 levels is largely unknown. The neuropeptide melanin-concentrating hormone (MCH) is mainly secreted during sleep and is involved...

  1. Adult Niemann-Pick disease type B with myositis ossificans: a case report

    Directory of Open Access Journals (Sweden)

    Russka Shumnalieva

    2016-07-01

    Full Text Available Niemann-Pick Disease (NPD is a rare autosomal recessive lysosomal lipid storage disorder. The disease is caused by gene mutations that affect the metabolism of sphingolipids. The dysfunctions cause sphingomyelin to accumulate in different organs. NPD includes forms with low and high levels of sphingomyelin. We report a case of a 34 year-old man with a family history of NPD type B who presented with hepatosplenomegaly, neurological deficiency, bone abnormalities, and myositis ossificans. The clinical, biochemical, and imaging data confirmed the combined diagnosis of NPD type B with myositis ossificans.

  2. Comparison of children's self-reports of depressive symptoms among different family interaction types in northern Taiwan

    Directory of Open Access Journals (Sweden)

    Yen Lee-Lan

    2007-06-01

    Full Text Available Abstract Background Previous research has shown that family interactions are associated with depressive symptoms in children. However, detailed classifications of family interaction types have not been studied thoroughly. This study aims to understand the types of family interactions children experience and to identify the specific types of family interactions that are associated with a higher risk of depressive symptoms in children. Methods Data used in the study was collected as part of the Child and Adolescent Behavior in Long term Evolution (CABLE project in 2003. CABLE is a longitudinal cohort study that commenced in 2001 and collects data annually from children in Taipei city and Hsinchu county in northern Taiwan. The data analyzed in this study was that obtained from the sixth graders (aged 11 to 12 years old in 2003. Of the 2,449 sixth graders, 51.2% were boys and 48.8% were girls. Factor analysis and cluster analysis were used to investigate the types of family interactions. One way ANOVA was used to establish the relationship between family interaction types and children's self-reports of depressive symptoms. Results Based on the results of factor analysis, the latent factors for family interactions included supporting activities, psychological control, parental discipline, behavioral supervision, and family conflict. After conducting cluster analysis using factor scores, four types of family interactions were revealed: supervised (29.66%, disciplined (13.56%, nurtured (40.96% and conflict (15.82%. Children from the disciplined or conflict families were more likely to report depressive symptoms. Children from the nurtured families were least likely to report depressive symptoms. Conclusion Family interactions can be classified into four different types, which are related to children's self-reports of depressive symptoms. The creation of a family interaction environment that is beneficial for children's mental health is an important

  3. Carrier concentration dependence of donor activation energy in n-type GaN epilayers grown on Si (1 1 1) by plasma-assisted MBE

    International Nuclear Information System (INIS)

    Kumar, Mahesh; Bhat, Thirumaleshwara N.; Roul, Basanta; Rajpalke, Mohana K.; Kalghatgi, A.T.; Krupanidhi, S.B.

    2012-01-01

    Highlights: ► The n-type GaN layers were grown by plasma-assisted molecular beam epitaxy. ► The optical characteristics of a donor level in Si-doped GaN were studied. ► Activation energy of a Si-related donor was estimated from temperature dependent PL measurements. ► PL peak positions, FWHM of PL and activation energies are found to be proportional to the cube root of carrier density. ► The involvement of donor levels is supported by the temperature-dependent electron concentration measurements. -- Abstract: The n-type GaN layers were grown by plasma-assisted MBE and either intentionally doped with Si or unintentionally doped. The optical characteristics of a donor level in Si-doped, GaN were studied in terms of photoluminescence (PL) spectroscopy as a function of electron concentration. Temperature dependent PL measurements allowed us to estimate the activation energy of a Si-related donor from temperature-induced decay of PL intensity. PL peak positions, full width at half maximum of PL and activation energies are found to be proportional to the cube root of carrier density. The involvement of donor levels is supported by the temperature-dependent electron concentration measurements.

  4. Adult type granulosa cell tumor in adult testis: report of a case and review of the literature

    Directory of Open Access Journals (Sweden)

    Zhanyong Bing

    2011-10-01

    Full Text Available Granulosa cell tumors can be classified into juvenile and adult types and more commonly occur in ovaries. Adult testicular granulosa cell tumors are extremely rare and only 29 cases of adult type have previously been reported. We report here a 28-year-old Caucasian man with a left testicular adult type granulosa cell tumor. The tumor measured 2.6 x 2.6 x 2.5 cm and was mitotically active (10/10 HPF. Immunohistochemical stains showed the tumor diffusely positive for inhibin and vimentin, and negative for epithelial membrane antigen, cytokeratins, synaptophysin, HMB-45, OCT-4, placental-like alkaline phosphatase and lymphoid markers . The reported granulosa cell tumors in adult testis were briefly reviewed.

  5. Atmospheric Dispersion of Various Types of Iodine in UAE in February and August

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sungyeop; Beeley, Philip A. [Khalifa Univ. of Science, Abu Dhabi (United Arab Emirates); Kim, Sungyeop; Chang, Soonheung; Lee, Kunjai [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2013-05-15

    The distribution ratio of these three types of iodine being released to the atmosphere under accident scenario is still not clearly reported because of its complex kinetics of chemical and physical process in the accidental condition. In this research, the dispersion behaviors of three kinds of iodine in the atmosphere have been considered in the UAE environment in winter and summer situations. Higher ground level concentration on the same downwind distance from the source appears in summer because of lower wind speed than that of winter. More lateral spreading of vertical downwind direction in summer has been confirmed because of less stable air than that of winter. Higher ground level concentrations have been appeared in order of particle type, organic gas type and elemental gas type of I-131 with given assumptions.

  6. Air pollutant concentrations near three Texas roadways, Part I: Ultrafine particles

    Science.gov (United States)

    Zhu, Yifang; Pudota, Jayanth; Collins, Donald; Allen, David; Clements, Andrea; DenBleyker, Allison; Fraser, Matt; Jia, Yuling; McDonald-Buller, Elena; Michel, Edward

    Vehicular emitted air pollutant concentrations were studied near three types of roadways in Austin, Texas: (1) State Highway 71 (SH-71), a heavily traveled arterial highway dominated by passenger vehicles; (2) Interstate 35 (I-35), a limited access highway north of Austin in Georgetown; and (3) Farm to Market Road 973 (FM-973), a heavily traveled surface roadway dominated by truck traffic. Air pollutants examined include carbon monoxide (CO), oxides of nitrogen (NO x), and carbonyl species in the gas-phase. In the particle phase, ultrafine particle (UFP) concentrations (diameter road were found to be the most important factors determining UFP concentrations near the roadways. Since wind directions were not consistent during the sampling periods, distances along wind trajectories from the roadway to the sampling points were used to study the decay characteristics of UFPs. Under perpendicular wind conditions, for all studied roadway types, particle number concentrations increased dramatically moving from the upwind side to the downwind side. The elevated particle number concentrations decay exponentially with increasing distances from the roadway with sharp concentration gradients observed within 100-150 m, similar to previously reported studies. A single exponential decay curve was found to fit the data collected from all three roadways very well under perpendicular wind conditions. No consistent pattern was observed for UFPs under parallel wind conditions. However, regardless of wind conditions, particle concentrations returned to background levels within a few hundred meters of the roadway. Within measured UFP size ranges, smaller particles (6-25 nm) decayed faster than larger ones (100-300 nm). Similar decay rates were observed among UFP number, surface, and volume.

  7. Influence of the turbulence typing scheme upon the cumulative frequency distribution of the calculated relative concentrations for different averaging times

    Energy Technology Data Exchange (ETDEWEB)

    Kretzschmar, J.G.; Mertens, I.

    1984-01-01

    Over the period 1977-1979, hourly meteorological measurements at the Nuclear Energy Research Centre, Mol, Belgium and simultaneous synoptic observations at the nearby military airport of Kleine Brogel, have been compiled as input data for a bi-Gaussian dispersion model. The available information has first of all been used to determine hourly stability classes in ten widely used turbulent diffusion typing schemes. Systematic correlations between different systems were rare. Twelve different combinations of diffusion typing scheme-dispersion parameters were then used for calculating cumulative frequency distributions of 1 h, 8 h, 16 h, 3 d, and 26 d average ground-level concentrations at receptors respectively at 500 m, 1 km, 2 km, 4 km and 8 km from continuous ground-level release and an elevated release at 100 m height. Major differences were noted as well in the extreme values, the higher percentiles, as in the annual mean concentrations. These differences are almost entirely due to the differences in the numercial values (as a function of distance) of the various sets of dispersion parameters actually in use for impact assessment studies. Dispersion parameter sets giving the lowest normalized ground-level concentration values for ground level releases give the highest results for elevated releases and vice versa. While it was illustrated once again that the applicability of a given set of dispersion parameters is restricted due to the specific conditions under which the given set derived, it was also concluded that systematic experimental work to validate certain assumptions is urgently needed.

  8. State Blood Alcohol Concentration (BAC) Testing and Reporting for Drivers Involved in Fatal Crashes : Current Practices, Results, and Strategies, 1997-2009

    Science.gov (United States)

    2012-08-01

    This report documents current State blood alcohol concentration (BAC) testing and reporting practices and results for drivers involved in fatal crashes. It summarizes known BAC results by State for the years 1997 to 2009 for both fatally injured and ...

  9. Report for the coal type committee meetings in fiscal 1988; 1987 nendo tanshu iinkai hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-03-01

    The first committee meeting was held on September 30, 1987. The major agenda included: a development plan for the basic research, and as the summary of the achievements in fiscal 1986, Chinese coal liquefaction tests, coal type surveys, coal resource surveys, and as the research plan for fiscal 1987, coal resource surveys (Alaskan coal and Kalimantan coal), coal type surveys, and Chinese coal liquefaction tests. The results thereon were reported and deliberated. The second committee meeting was held on February 25, 1988. The agenda included: an interim report on the Chinese coal liquefaction tests, coal type surveys, coal resource surveys, (Alaskan coal and Kalimantan coal), as the interim report on the research achievements in fiscal 1987. Among the agenda, especially on the Chinese coal liquefaction tests, the data of the tests performed by the Chinese side and presented at the Japan-China joint technology sub-committee were introduced in detail, having drawn attention of the attendants. The first committee meeting reported the result of the autoclave test carried out by the Chinese side, the result of operation of the small continuous device (0.1 t/d) in fiscal 1986, and the result of the autoclave test performed by Mitsui Engineering and Shipbuilding for comparison. The second committee meeting reported the result of continuous operation implemented in China from August through September 1987 in the Chinese coal liquefaction test. (NEDO)

  10. Plasma osteoprotegerin concentrations in peripheral sensory neuropathy in Type 1 and Type 2 diabetic patients

    DEFF Research Database (Denmark)

    Nybo, M; Poulsen, M K; Grauslund, J

    2010-01-01

    Osteoprotegerin (OPG) has been linked to different diabetes complications, including cardiovascular disease, and new findings have indicated a specific role in diabetic peripheral neuropathy, but the exact mechanism is unknown. To investigate a possible association between OPG and diabetic...... peripheral sensory neuropathy, we therefore analysed plasma OPG in Type 1 and Type 2 diabetic patients with and without peripheral neuropathy....

  11. Plasma concentrations of soluble urokinase-type plasminogen activator receptor are increased in patients with malaria and are associated with a poor clinical or a fatal outcome

    DEFF Research Database (Denmark)

    Ostrowski, Sisse R; Ullum, Henrik; Goka, Bamenla Q

    2005-01-01

    PAR are associated with disease severity in malaria. METHODS: At admission to the hospital, plasma concentrations of suPAR were measured by ELISA in samples from 645 African children with clinical symptoms of malaria: 478 had malaria, and 167 had a blood film negative for Plasmodium parasites. Fourteen healthy......BACKGROUND: Blood concentrations of soluble urokinase-type plasminogen activator receptor (suPAR) are increased in conditions with immune activation, and high concentrations of suPAR often predict a poor clinical outcome. This study explored the hypothesis that high plasma concentrations of su......: If the plasma concentration of suPAR reflects the extent of parasite-induced immune activation, this may explain why a high concentration of suPAR is associated with a poor clinical outcome in patients with malaria....

  12. [Effects of different types and concentration of oral sweet solution on reducing neonatal pain during heel lance procedures].

    Science.gov (United States)

    Leng, Hong-yao; Zheng, Xian-lan; Yan, Li; Zhang, Xian-hong; He, Hua-yun; Xiang, Ming

    2013-09-01

    To compare the effect of different types and concentrations of sweet solutions on neonatal pain during heel lance procedure. Totally 560 full term neonates (male 295, female 265) were randomized into 7 groups:placebo group (plain water), 10% glucose, 25% glucose, 50% glucose, 12% sucrose, 24% sucrose and 30% sucrose groups.In each group, 2 ml corresponding oral solutions were administered through a syringe by dripping into the neonate's mouth 2 minute before heel lance. The procedure process was recorded by videos, from which to collect heart rate, oxygen saturation and pain score 1 min before puncture, 3, 5 and 10 min after puncture. The average heart rate increase 3, 5 and 10 min after procedure in the 25% and 50% glucose groups, 12% and 24% and 30% sucrose groups was significantly lower than those in the placebo group (P lance (both P lance, but the best concentration of sucrose for pain relief needs further study.

  13. Controlled production of camembert-type cheeses: part III role of the ripening microflora on free fatty acid concentrations.

    Science.gov (United States)

    Leclercq-Perlat, Marie-Noëlle; Corrieu, Georges; Spinnler, Henry-Eric

    2007-05-01

    Phenomena generating FFAs, important flavour precursors, are significant in cheese ripening. In Camembert-like cheeses, it was intended to establish the relationships between the dynamics of FFA concentrations changes and the succession of ripening microflora during ripening. Experimental Camembert-type cheeses were prepared in duplicate from pasteurised milk inoculated with Kluyveromyces lactis, Geotrichum candidum, Penicillium camemberti, and Brevibacterium aurantiacum under aseptic conditions. For each cheese and each cheesy medium, concentrations of FFAs with odd-numbered carbons, except for 9:0 and 13:0, did not change over time. For long-chain FFAs, concentrations varied with the given cheese part (rind or core). K. lactis produced only short or medium-chain FFAs during its growth and had a minor influence on caproic, caprylic, capric, and lauric acids in comparison with G. candidum, the most lipolytic of the strains used here. It generated all short or medium-chain FFAs (4:0-12:0) during its exponential and slowdown growth periods and only long-chain ones (14:0-18:0) during its stationary phase. Pen. camemberti produced more long-chain FFAs (14:0-18:0) during its sporulation. Brev. aurantiacum did not generate any FFAs. The evidence of links between specific FFAs and the growth of a given microorganism is shown.

  14. Freeze concentration of dairy products Phase 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Best, D.E.; Vasavada, K.C.

    1993-09-01

    An efficient, electrically driven freeze concentration system offers potential for substantially increasing electricity demand while providing the mature dairy industry with new products for domestic and export markets together with enhanced production efficiencies. Consumer tests indicate that dairy products manufactured from freeze-concentrated ingredients are either preferred or considered equivalent in quality to fresh milk-based products. Economic analyses indicate that this technology should be competitive with thermal evaporation processes on a commercial basis.

  15. Poverty concentration and determinants in China's urban low-income neighbourhoods and social groups.

    Science.gov (United States)

    He, Shenjing; Wu, Fulong; Webster, Chris; Liu, Yuting

    2010-01-01

    Based on a large-scale household survey conducted in 2007, this article reports on poverty concentration and determinants in China's low-income neighbourhoods and social groups. Three types of neighbourhood are recognized: dilapidated inner-city neighbourhoods, declining workers' villages and urban villages. Respondents are grouped into four categories: working, laid-off/unemployed and retired urban residents, together with rural migrants. We first measure poverty concentration across different types of neighbourhood and different groups. The highest concentrations are found in dilapidated inner-city neighbourhoods and among the laid-off/unemployed. Mismatches are found between actual hardships, sense of deprivation and distribution of social welfare provision. Second, we examine poverty determinants. Variations in institutional protection and market remuneration are becoming equally important in predicting poverty generation, but are differently associated with it in the different neighbourhoods and groups. As China's urban economy is increasingly shaped by markets, the mechanism of market remuneration is becoming a more important determinant of poverty patterns, especially for people who are excluded from state institutions, notably laid-off workers and rural migrants.

  16. One-hour and two-hour postload plasma glucose concentrations are comparable predictors of type 2 diabetes mellitus in Southwestern Native Americans.

    Science.gov (United States)

    Paddock, Ethan; Hohenadel, Maximilian G; Piaggi, Paolo; Vijayakumar, Pavithra; Hanson, Robert L; Knowler, William C; Krakoff, Jonathan; Chang, Douglas C

    2017-09-01

    Elevated 2-h plasma glucose concentration (2 h-PG) during a 75 g OGTT predict the development of type 2 diabetes mellitus. However, 1-h plasma glucose concentration (1 h-PG) is associated with insulin secretion and may be a better predictor of type 2 diabetes. We aimed to investigate the association between 1 h-PG and 2 h-PG using gold standard methods for measuring insulin secretion and action. We also compared 1 h-PG and 2 h-PG as predictors of type 2 diabetes mellitus. This analysis included adult volunteers without diabetes, predominantly Native Americans of Southwestern heritage, who were involved in a longitudinal epidemiological study from 1965 to 2007, with a baseline OGTT that included measurement of 1 h-PG. Group 1 (n = 716) underwent an IVGTT and hyperinsulinaemic-euglycaemic clamp for measurement of acute insulin response (AIR) and insulin-stimulated glucose disposal (M), respectively. Some members of Group 1 (n = 490 of 716) and members of a second, larger, group (Group 2; n = 1946) were followed-up to assess the development of type 2 diabetes (median 9.0 and 12.8 years follow-up, respectively). Compared with 2 h-PG (r = -0.281), 1 h-PG (r = -0.384) was more closely associated with AIR, whereas, compared with 1 h-PG (r = -0.340), 2 h-PG (r = -0.408) was more closely associated with M. Measures of 1 h-PG and 2 h-PG had similar abilities to predict type 2 diabetes, which did not change when both were included in the model. A 1 h-PG cut-off of 9.3 mmol/l provided similar levels of sensitivity and specificity as a 2 h-PG cut-off of 7.8 mmol/l; the latter is used to define impaired glucose tolerance, a recognised predictor of type 2 diabetes mellitus. The 1 h-PG was associated with important physiological predictors of type 2 diabetes and was as effective as 2 h-PG for predicting type 2 diabetes mellitus. The 1 h-PG is, therefore, an alternative method of identifying individuals with an elevated risk of type 2 diabetes

  17. Source Reduction Effectiveness at Fuel Contaminated Sites, Technical Summary Report

    National Research Council Canada - National Science Library

    2000-01-01

    This report assesses the degree to which various types or engineered source-reduction efforts at selected fuel-contaminated sites have resulted in decreasing concentrations of fuel constituents dissolved in groundwater...

  18. Hole traps associated with high-concentration residual carriers in p-type GaAsN grown by chemical beam epitaxy

    Energy Technology Data Exchange (ETDEWEB)

    Elleuch, Omar, E-mail: mr.omar.elleuch@gmail.com; Wang, Li; Lee, Kan-Hua; Demizu, Koshiro; Ikeda, Kazuma; Kojima, Nobuaki; Ohshita, Yoshio; Yamaguchi, Masafumi [Toyota Technological Institute, 2-12-1 Hisakata, Tempaku, Nagoya 468-8511 (Japan)

    2015-01-28

    The hole traps associated with high background doping in p-type GaAsN grown by chemical beam epitaxy are studied based on the changes of carrier concentration, junction capacitance, and hole traps properties due to the annealing. The carrier concentration was increased dramatically with annealing time, based on capacitance–voltage (C–V) measurement. In addition, the temperature dependence of the junction capacitance (C–T) was increased rapidly two times. Such behavior is explained by the thermal ionization of two acceptor states. These acceptors are the main cause of high background doping in the film, since the estimated carrier concentration from C–T results explains the measured carrier concentration at room temperature using C–V method. The acceptor states became shallower after annealing, and hence their structures are thermally unstable. Deep level transient spectroscopy (DLTS) showed that the HC2 hole trap was composed of two signals, labeled HC21 and HC22. These defects correspond to the acceptor levels, as their energy levels obtained from DLTS are similar to those deduced from C–T. The capture cross sections of HC21 and HC22 are larger than those of single acceptors. In addition, their energy levels and capture cross sections change in the same way due to the annealing. This tendency suggests that HC21 and HC22 signals originate from the same defect which acts as a double acceptor.

  19. Hole traps associated with high-concentration residual carriers in p-type GaAsN grown by chemical beam epitaxy

    International Nuclear Information System (INIS)

    Elleuch, Omar; Wang, Li; Lee, Kan-Hua; Demizu, Koshiro; Ikeda, Kazuma; Kojima, Nobuaki; Ohshita, Yoshio; Yamaguchi, Masafumi

    2015-01-01

    The hole traps associated with high background doping in p-type GaAsN grown by chemical beam epitaxy are studied based on the changes of carrier concentration, junction capacitance, and hole traps properties due to the annealing. The carrier concentration was increased dramatically with annealing time, based on capacitance–voltage (C–V) measurement. In addition, the temperature dependence of the junction capacitance (C–T) was increased rapidly two times. Such behavior is explained by the thermal ionization of two acceptor states. These acceptors are the main cause of high background doping in the film, since the estimated carrier concentration from C–T results explains the measured carrier concentration at room temperature using C–V method. The acceptor states became shallower after annealing, and hence their structures are thermally unstable. Deep level transient spectroscopy (DLTS) showed that the HC2 hole trap was composed of two signals, labeled HC21 and HC22. These defects correspond to the acceptor levels, as their energy levels obtained from DLTS are similar to those deduced from C–T. The capture cross sections of HC21 and HC22 are larger than those of single acceptors. In addition, their energy levels and capture cross sections change in the same way due to the annealing. This tendency suggests that HC21 and HC22 signals originate from the same defect which acts as a double acceptor

  20. Facial Plexiform neurofibromatosis in a patient with neurofibromatosis type1: a case report

    Directory of Open Access Journals (Sweden)

    Iffat Hassan

    2012-01-01

    Full Text Available Plexiform neurofibroma is a poorly circumscribed, diffuse enlargement of neural sheets that typically involves major nerve trunks of the head and neck region because of the rich innervations of this area. It is a benign tumor and is a virtually pathognomonic and often disabling feature of neurofibromatosis type 1 (NF-1 or Von Recklinghausen’s disease. We hereby report a case of facial neurofibroma in an adult female with neurofibromatosis type 1 (NF-1.

  1. Using multiclass classification to automate the identification of patient safety incident reports by type and severity.

    Science.gov (United States)

    Wang, Ying; Coiera, Enrico; Runciman, William; Magrabi, Farah

    2017-06-12

    Approximately 10% of admissions to acute-care hospitals are associated with an adverse event. Analysis of incident reports helps to understand how and why incidents occur and can inform policy and practice for safer care. Unfortunately our capacity to monitor and respond to incident reports in a timely manner is limited by the sheer volumes of data collected. In this study, we aim to evaluate the feasibility of using multiclass classification to automate the identification of patient safety incidents in hospitals. Text based classifiers were applied to identify 10 incident types and 4 severity levels. Using the one-versus-one (OvsO) and one-versus-all (OvsA) ensemble strategies, we evaluated regularized logistic regression, linear support vector machine (SVM) and SVM with a radial-basis function (RBF) kernel. Classifiers were trained and tested with "balanced" datasets (n_ Type  = 2860, n_ SeverityLevel  = 1160) from a state-wide incident reporting system. Testing was also undertaken with imbalanced "stratified" datasets (n_ Type  = 6000, n_ SeverityLevel =5950) from the state-wide system and an independent hospital reporting system. Classifier performance was evaluated using a confusion matrix, as well as F-score, precision and recall. The most effective combination was a OvsO ensemble of binary SVM RBF classifiers with binary count feature extraction. For incident type, classifiers performed well on balanced and stratified datasets (F-score: 78.3, 73.9%), but were worse on independent datasets (68.5%). Reports about falls, medications, pressure injury, aggression and blood products were identified with high recall and precision. "Documentation" was the hardest type to identify. For severity level, F-score for severity assessment code (SAC) 1 (extreme risk) was 87.3 and 64% for SAC4 (low risk) on balanced data. With stratified data, high recall was achieved for SAC1 (82.8-84%) but precision was poor (6.8-11.2%). High risk incidents (SAC2) were confused

  2. Pilot-Reported Beta-Blockers Identified by Forensic Toxicology Analysis of Postmortem Specimens.

    Science.gov (United States)

    Canfield, Dennis V; Dubowski, Kurt M; Whinnery, James M; Forster, Estrella M

    2018-01-01

    This study compared beta-blockers reported by pilots with the medications found by postmortem toxicology analysis of specimens received from fatal aviation accidents between 1999 and 2015. Several studies have compared drugs using the standard approach: Compare the drug found by toxicology analysis with the drug reported by the pilot. This study uniquely examined first the pilot-reported medication and then compared it to that detected by toxicology analysis. This study will serve two purposes: (i) to determine the capability of a toxicology laboratory to detect reported medications, and (ii) to identify pilots with medications below detectable limits. All information required for this study was extracted from the Toxicology Data Base system and was searched using ToxFlo or SQL Server Management Studio. The following information was collected and analyzed: pilot-reported trade and/or generic drug, date specimens received, time of accident, type of aviation operations (CFR), state, pilot level, age, class of medical, specimen type, specimen concentration, dose reported, frequency reported associated with the accident, quantity reported, National Transportation Safety Board (NTSB) accident event number, and all NTSB reports. There were 319 pilots that either reported taking a beta-blocker or were found to be taking a beta-blocker by postmortem toxicology analysis. Time of death, therapeutic concentration and specimen type were found to be factors in the ability of the laboratory to detect beta-blockers. Beta-blockers taken by pilots will, in most cases, be found by a competent postmortem forensic toxicology laboratory at therapeutic concentrations. The dose taken by the pilot was not found to be a factor in the ability of the laboratory to identify beta-blockers. Time of dose, route of administration, specimen tested and therapeutic concentration of the drug were found to be factors in the ability of the laboratory to identify beta-blockers in postmortem specimens

  3. Photovoltaic static concentrator analysis

    Science.gov (United States)

    Almonacid, G.; Luque, A.; Molledo, A. G.

    1984-12-01

    Ray tracing is the basis of the present analysis of truncated bifacial compound parabolic concentrators filled with a dielectric substance, which are of interest in photovoltaic applications where the bifacial cells allow higher static concentrations to be achieved. Among the figures of merit for this type of concentrator, the directional intercept factor plays a major role and is defined as the ratio of the power of the collector to that at the entry aperture, in a lossless concentrator illuminated by light arriving from a given direction. A procedure for measuring outdoor, full size panels has been developed, and a correction method for avoiding the effect of unwanted diffuse radiation during the measurements is presented.

  4. Concentrations of selected contaminants in cabin air of airbus aircrafts.

    Science.gov (United States)

    Dechow, M; Sohn, H; Steinhanses, J

    1997-07-01

    The concentrations of selected air quality parameters in aircraft cabins were investigated including particle numbers in cabin air compared to fresh air and recirculation air, the microbiological contamination and the concentration of volatile organic compounds (VOC). The Airbus types A310 of Swissair and A340 of Lufthansa were used for measurements. The particles were found to be mainly emitted by the passengers, especially by smokers. Depending on recirculation filter efficiency the recirculation air contained a lower or equal amount of particles compared to the fresh air, whereas the amount of bacteria exceeded reported concentrations within other indoor spaces. The detected species were mainly non-pathogenic, with droplet infection over short distances identified as the only health risk. The concentration of volatile organic compounds (VOC) were well below threshold values. Ethanol was identified as the compound with the highest amount in cabin air. Further organics were emitted by the passengers--as metabolic products or by smoking--and on ground as engine exhaust (bad airport air quality). Cleaning agents may be the source of further compounds.

  5. Novel concept of nonimaging single reflection solar energy concentrator

    Energy Technology Data Exchange (ETDEWEB)

    Gasparovsky, D.

    2004-07-01

    Many solar applications require temperatures higher than those that can be achieved by common flat-plate collectors. Temperatures over 100 C are necessary e.g. for industrial process heat. Such temperatures can be obtained by means of solar energy concentrators. Advantages of concentrating the solar radiation can bring in addition to higher temperatures also decrease in heat losses and material savings due to smaller size of absorber, if taking into account that costs for material absorber per square meter can be possibly higher than costs for e.g. concentrating mirrors. On the other hand, using the concentration, two other kinds of losses will raise: losses of diffuse radiation and optical losses. There exist a variety of solar energy concentrators for different purposes. For lowtemperature applications, inexpensive concentrators of diffuse radiation can be used. For these concentrators, acceptance angle A defines the ability to concentrate the diffuse radiation and also its concentration factor C. To this class of concentrators belongs e.g. nonimaging types like CPC (Compound Parabolic Concentrator), V-trough types, cylindrical concentrators etc. This paper deals with development of a new type of concentrator, novel concept of which is based on functionality of CPC by means of flat mirrors, primarily designed for needs of SME's (Small and Medium Enterprises). The CLON project is being ellaborated under the 5th Framework Programme of the EU. (orig.)

  6. Systematic review of the concentrations of oligosaccharides in human milk.

    Science.gov (United States)

    Thurl, Stephan; Munzert, Manfred; Boehm, Günther; Matthews, Catherine; Stahl, Bernd

    2017-11-01

    Oligosaccharides are the third largest solid component in human milk. These diverse compounds are thought to have numerous beneficial functions in infants, including protection against infectious diseases. The structures of more than 100 oligosaccharides in human milk have been elucidated so far. The aim of this review was to identify the main factors that affect the concentrations of oligosaccharides in human milk and to determine whether it is possible to calculate representative and reliable mean concentrations. A comprehensive literature search on oligosaccharide concentrations in human milk was performed in 6 electronic databases: BIOSIS, Current Contents Search, Embase, Lancet Titles, MEDLINE and PubMed. The initial search resulted in 1363 hits. After the elimination of duplicates, the literature was screened. The application of strict inclusion criteria resulted in 21 articles selected. Oligosaccharide concentrations, both mean values and single values, reported in the literature were sorted by gestational age, secretor status of mothers, and defined lactation periods. Mean concentrations, including confidence limits, of 33 neutral and acidic oligosaccharides reported could be calculated. Concentrations of oligosaccharides in human milk show variations that are dependent on both the secretor type of the mother and the lactation period as examined by analyses of variance. In addition, large interlaboratory variations in the data were observed. Worldwide interlaboratory quantitative analyses of identical milk samples would be required to identify the most reliable methods of determining concentrations of oligosaccharides in human milk. The data presented here contribute to the current knowledge about the composition and quantities of oligosaccharides in human milk and may foster greater understanding of the biological functions of these compounds. © The Author(s) 2017. Published by Oxford University Press on behalf of the International Life Sciences Institute.

  7. Evaluation of Web-based Dietary Assessment Software for Children: comparing reported fruit, juice and vegetable intakes with plasma carotenoid concentration and school lunch observations.

    Science.gov (United States)

    Biltoft-Jensen, Anja; Bysted, Anette; Trolle, Ellen; Christensen, Tue; Knuthsen, Pia; Damsgaard, Camilla T; Andersen, Lene F; Brockhoff, Per; Tetens, Inge

    2013-07-14

    Web-based Dietary Assessment Software for Children (WebDASC) was developed to estimate dietary intake in a school meal intervention study among 8- to 11-year-old Danish children. The present study validates self-reported fruit, juice and vegetable (FJV) intakes in 8- to 11-year-old children by comparing intake with plasma carotenoid concentration, and by comparing the reported FJV intake to actually eaten FJV, as observed by a photographic method. A total of eighty-one children, assisted by parents, reported their diet for seven consecutive days. For the same five schooldays as they reported their diet, the children's school lunch was photographed and weighed before and after eating. In the week after the diet reporting, fasting blood samples were taken. Self-reported intake of FJV and estimated intake of carotenoids were compared with plasma carotenoid concentration. Accuracy of self-reported food and FJV consumption at school lunch was measured in terms of matches, intrusion, omission and faults, when compared with images and weights of lunch intake. Self-reported intake of FJV was significantly correlated with the total carotenoid concentration (0·58) (Pjuice consumption showed higher correlations than vegetables with plasma carotenoid concentration (0·38 and 0·42 v. 0·33) (P< 0·01). A total of 82 % of the participants fell into the same or adjacent quartiles when cross-classified by FJV intake and carotenoids biomarkers. WebDASC attained 82 % reporting matches overall and a higher percentage match for reporting fruits compared with beverages. The present study indicated that WebDASC can be used to rank 8- to 11-year-old Danish children according to their intake of FJV overall and at school meals.

  8. Study on high concentration solar concentrator using a Fresnel lens with a secondary concentrator; Fresnel lens to niji shukokei wo mochiita solar chemistry yo kobairitsu shukokei ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Aihara, T; Suzuki, A; Fujibayashi, K [Tokyo University of Agriculture and Technology, Tokyo (Japan)

    1997-11-25

    A high concentration light collection system for solar chemistry was devised by using an inexpensive Fresnel lens in a primary concentration system and a conical type concentrator in a secondary concentration system. A Fresnel lens alone would not achieve sufficiently high light collecting magnification to attain high temperatures because of restrictions in the opening angle as seen from a focus. Therefore, a secondary concentration system was installed on a focus for an attempt of stopping. Reflection plane of a three-dimensional compound parabolic concentrator (CPC) is a rotary parabolic plane, whose process is expensive because of its surface processing accuracy. Therefore, a conical type concentrator was employed as a secondary concentration system. This system may not be capable of achieving as high concentration as in the CPC, but its shape is simple and it is inexpensive. In its optimization, a complete black body surface placed in vacuum atmosphere was hypothesized as a light concentrating part for the secondary concentration system to calculate heat collecting efficiencies at respective temperature settings. Using simultaneously the secondary concentration system, rather than collecting heat by using a Fresnel lens alone, has attained as high value as from 5.99% (500 degC) to 43.47% (1400 degC). Economical high-temperature heat collection of solar chemistry level may be possible by using a Fresnel lens and a conical secondary concentration system. 1 ref., 7 figs., 2 tabs.

  9. The importance of different frequency bands in predicting subcutaneous glucose concentration in type 1 diabetic patients.

    Science.gov (United States)

    Lu, Yinghui; Gribok, Andrei V; Ward, W Kenneth; Reifman, Jaques

    2010-08-01

    We investigated the relative importance and predictive power of different frequency bands of subcutaneous glucose signals for the short-term (0-50 min) forecasting of glucose concentrations in type 1 diabetic patients with data-driven autoregressive (AR) models. The study data consisted of minute-by-minute glucose signals collected from nine deidentified patients over a five-day period using continuous glucose monitoring devices. AR models were developed using single and pairwise combinations of frequency bands of the glucose signal and compared with a reference model including all bands. The results suggest that: for open-loop applications, there is no need to explicitly represent exogenous inputs, such as meals and insulin intake, in AR models; models based on a single-frequency band, with periods between 60-120 min and 150-500 min, yield good predictive power (error bands produce predictions that are indistinguishable from those of the reference model as long as the 60-120 min period band is included; and AR models can be developed on signals of short length (approximately 300 min), i.e., ignoring long circadian rhythms, without any detriment in prediction accuracy. Together, these findings provide insights into efficient development of more effective and parsimonious data-driven models for short-term prediction of glucose concentrations in diabetic patients.

  10. Separation, fractionation, concentration and drying of food products: Technology progress report, October 1, 1984-March 3, 1987

    Energy Technology Data Exchange (ETDEWEB)

    Rose, W. W.; Pederson, L. D.; Merlo, C. A.; Brewbaker, P. L.

    1987-11-01

    This report describes the first and second phases of a three phase project, the object of which is to develop energy efficient separation, concentration, and drying processes for food products, especially juice products, in order to reduce energy requirements and their associated costs for processing, preservation, and transportation. Presently in juice processing, much water is eliminated through evaporation. However, there are significant limits to the current evaporation technology. If, however, the juice could be separated, prior to evaporation, into liquid and solid fractions, and the liquid concentrated further, the containerization and transportation costs could be significantly reduced. Separation methods investigated in this project are: vacuum filtration, centrifugation, and crossflow microfiltration.

  11. Recurrent rhabdomyolysis and glutaric aciduria type I: a case report and literature review.

    Science.gov (United States)

    Qian, Gu-Ling; Hong, Fang; Tong, Fan; Fu, Hai-Dong; Liu, Ai-Min

    2016-08-01

    Glutaric acidemia type I (GA-I) is a rare metabolic disorder caused by mutation of the glutaryl- CoA dehydrogenase (GCDH) gene. The occurrence of rhabdomyolysis with GA-I is extremely rare. We reported a child with recurrent rhabdomyolysis and undiagnosed glutaric acidemia type I (GA-I). And a literature review was performed. A 4.5-year-old girl was admitted to our hospital due to recurrent rhabdomyolysis for 3 times within three years. At the third admission, she was diagnosed with GA-I by biochemical testing and mutation analysis. The girl was found to have a serine to leucine replacement mutation of the GCDH gene in exon 8 at position 764. Other three patients with rhabdomyolysis and GA-I were discovered by literature searching. This report highlights that patients with GA-I may have an increased risk of rhabdomyolysis.

  12. Balo's concentric sclerosis; value of magnetic resonance imaging in diagnosis

    International Nuclear Information System (INIS)

    Singh, S.; Kuruvilla, A.; Korah, I.P.; Alexander, M.

    1999-01-01

    We report two cases of Balo's concentric sclerosis that demonstrate the typical magnetic resonance imaging (MRI) findings of concentric rings of demyelination involving the superficial and deep white matter and sparing the cortex. In both cases biopsy was not performed as MRI findings and multi-mode evoked potential studies were consistent with demyelinating illness. The theories regarding the pathogenesis of this peculiar appearance are briefly reviewed. Balo's concentric sclerosis is a very rare type of demyelinating disease characterized pathologically by large alternating lamellae of demyelinated and myelinated white matter arranged in a concentric pattern. This progressive disease is more often found in young male adults and is more common in the Philippines. Balo's concentric sclerosis is considered an unusual variant of multiple sclerosis (MS); however, some authors believe it to be a different entity. Although the pathogenesis of the concentric sclerosis is debated, the cause of demyelination is generally presumed to be the same as that of multiple sclerosis. There is striking resemblance between the magnetic resonance (MR) appearance and the histopathological features of MS. Not all cases may show a typical MR appearance. Prior to MR imaging, most of them were diagnosed at post-mortem. To our knowledge, few cases have been diagnosed by MR imaging in life. Copyright (1999) Blackwell Science Pty Ltd

  13. Characterization of acetate-utilizing methanogenic bacteria, depending on varying acetate concentrations, in a biogas plant. Phase 1

    International Nuclear Information System (INIS)

    Ahring, B.K.

    1994-12-01

    The present report contains the results of a project concerning behaviour of acetate-utilizing methanogenic bacteria in mesophilic and thermophilic biogas plants, collected in 1992 - 1994 period. Labelled acetates (2-C 14 -CH 3 COOH) have been used to characterize the types of methane bacteria populations in the Danish biogas plants, the optimum acetate concentration for these bacteria and acetate metabolism in mesophilic and thermophilic biogas reactors with low acetate concentrations. 2 publications are included. (EG)

  14. Defect clustering in concentrated alloys during irradiation

    International Nuclear Information System (INIS)

    Hashimoto, T.; Shigenaka, N.; Fuse, M.

    1992-01-01

    A rate theory based model is presented to investigate the kinetics of interstitial clustering processes in a face-centered cubic (fcc) binary alloy containing A- and B-atoms. Three types of interstitial dumbbells, AA-, BB- and AB-type dumbbells, are considered. Conversions between these interstitial dumbbells are explicitly introduced into the formulation, based on the consideration of dumbbell configurations and movements. A di- interstitial is assumed to be the nucleus of a dislocation loop. Reactions of point defect production by irradiation, mutual recombination of an interstitial and a vacancy, dislocation loop nucleation and their growth are included in the model. Parameter values are chosen based on the atom size of the alloy elements, and dislocation loop formation kinetics are investigated while varying alloy compositions. Two different types of kinetics are obtained in accordance with the dominant loop nucleus types. Conversions between interstitial dumbbells are important in the determination of the interstitial dumbbell concentration ratios, of the dominant nucleus types, and consequently, the loop formation kinetics. Dislocation loop concentration decreases with increasing undersized atom content, but dose rate and temperature dependence of loop concentration are insensitive to alloy compositions. (author)

  15. Hybrid entanglement concentration assisted with single coherent state

    International Nuclear Information System (INIS)

    Guo Rui; Zhou Lan; Sheng Yu-Bo; Gu Shi-Pu; Wang Xing-Fu

    2016-01-01

    Hybrid entangled state (HES) is a new type of entanglement, which combines the advantages of an entangled polarization state and an entangled coherent state. HES is widely discussed in the applications of quantum communication and computation. In this paper, we propose three entanglement concentration protocols (ECPs) for Bell-type HES, W-type HES, and cluster-type HES, respectively. After performing these ECPs, we can obtain the maximally entangled HES with some success probability. All the ECPs exploit the single coherent state to complete the concentration. These protocols are based on the linear optics, which are feasible in future experiments. (paper)

  16. Type III Osteogenesis Imperfecta With Dentinogenesis Imperfecta - A Case Report And review of Literature

    Directory of Open Access Journals (Sweden)

    Prabal Pal

    2003-01-01

    Full Text Available Osteogenesis Imperfecta is a genetic disorder affecting approximately 20,000 U.S. population with multiple fracture of the bone. The, actual literature of the number of patients suffering from Osteogenesis Impcrfecta in Indian Population is still nor available. This is a case of a male patient who presented to the O.PD. of Subharati Dental College with history of pain ands swelling in the left lower posterior teeth region. On detail workout of the case it was found that the patient had Dentinogenesis Imperfecta Type I with Type III Osteogenesis Imperfecta. Very few cases with such presentation is reported in Indian Literature. The following report presents the clinical findings of Osteogcnesis Imperfecta and an associated review of Literature.

  17. Comparison of two-concentration with multi-concentration linear regressions: Retrospective data analysis of multiple regulated LC-MS bioanalytical projects.

    Science.gov (United States)

    Musuku, Adrien; Tan, Aimin; Awaiye, Kayode; Trabelsi, Fethi

    2013-09-01

    Linear calibration is usually performed using eight to ten calibration concentration levels in regulated LC-MS bioanalysis because a minimum of six are specified in regulatory guidelines. However, we have previously reported that two-concentration linear calibration is as reliable as or even better than using multiple concentrations. The purpose of this research is to compare two-concentration with multiple-concentration linear calibration through retrospective data analysis of multiple bioanalytical projects that were conducted in an independent regulated bioanalytical laboratory. A total of 12 bioanalytical projects were randomly selected: two validations and two studies for each of the three most commonly used types of sample extraction methods (protein precipitation, liquid-liquid extraction, solid-phase extraction). When the existing data were retrospectively linearly regressed using only the lowest and the highest concentration levels, no extra batch failure/QC rejection was observed and the differences in accuracy and precision between the original multi-concentration regression and the new two-concentration linear regression are negligible. Specifically, the differences in overall mean apparent bias (square root of mean individual bias squares) are within the ranges of -0.3% to 0.7% and 0.1-0.7% for the validations and studies, respectively. The differences in mean QC concentrations are within the ranges of -0.6% to 1.8% and -0.8% to 2.5% for the validations and studies, respectively. The differences in %CV are within the ranges of -0.7% to 0.9% and -0.3% to 0.6% for the validations and studies, respectively. The average differences in study sample concentrations are within the range of -0.8% to 2.3%. With two-concentration linear regression, an average of 13% of time and cost could have been saved for each batch together with 53% of saving in the lead-in for each project (the preparation of working standard solutions, spiking, and aliquoting). Furthermore

  18. Separation, fractionation, concentration and drying of food products: Final report, March 4, 1987--March 31, 1988

    Energy Technology Data Exchange (ETDEWEB)

    Merlo, C.A.; Rose, W.W.; Pedersen, L.D.; Brewbaker, P.L.

    1988-03-01

    This project studied energy efficient processes for separation, fractionation, concentration, drying, and recombination of food products, in order to reduce energy requirements for processing, preservation, and transportation. The project had three phases. In the laboratory-scale phase, results of which are summarized in this report, tomato puree was separated by three methods: conventional vacuum filtration, centrifugation, and crossflow microfiltration to produce pulp and serum. Three methods of recombination were examined: homogenizing, stomacher blending, and static (in-line) mixing. Satisfactory recombined purees were obtained. In addition, after centrifugation, the pulp was rinsed producing rinsed-pulp, and the rinse water was added to the serum producing rinse/serum. The rinse/serum was concentrated by evaporation. This was recombined with the rinsed-pulp and water producing satisfactory puree. 11 refs., 18 figs., 18 tabs.

  19. Self-reported sunscreen use and urinary benzophenone-3 concentrations in the United States: NHANES 2003–2006 and 2009–2012

    International Nuclear Information System (INIS)

    Zamoiski, Rachel D.; Cahoon, Elizabeth K.; Michal Freedman, D.; Linet, Martha S.

    2015-01-01

    Background: Sunscreens protect against skin cancer and other harmful effects of solar ultraviolet radiation (UVR). Epidemiologic and public health surveys often rely on self-reported sunscreen use to estimate sun exposure and avoidance, but questions remain about the validity of self-reports. Benzophenone-3 (BP-3), a common sunscreen ingredient, can be detected in the urine. Prior studies suggest that BP-3 concentrations increase after application of sunscreen. Objectives: The goal of this study was to assess the validity of self-reported frequency of sunscreen use in relation to urinary BP-3 concentrations in a representative sample of the general US population, including in sub-groups defined by age, sex and race/ethnicity. Methods: To assess the relationship between categorical self-reported sunscreen use and creatinine-corrected urinary BP-3 concentrations, we conducted a linear regression adjusted for age, sex, race/ethnicity, six-month time period, body mass index, education, and sun avoidance behaviors. We tested for effect modification by age, sex, ethnicity and time period of measurement using multiplicative interaction terms and a F test. Results: BP-3 was positively associated with self-reported frequency of sunscreen use across all ages, sexes, race/ethnicities, and time periods. Crude and multivariate adjusted models were all statistically significant. R-square was relatively low for all models, ranging from 0.15 to 0.43. Conclusions: Urinary BP-3 is positively associated with self-reported frequency of sunscreen use in the general US population, even in groups with overall low sunscreen use. These results suggest that self-report is a valid, although weak, way of assessing relative frequencies of sunscreen usage in a population-based study. - Highlights: • Urinary benzophenone-3 (BP-3) is a metabolite of a common sunscreen ingredient. • We modeled urinary BP-3 against self-reported sunscreen usage. • We observed a positive association between

  20. Self-reported sunscreen use and urinary benzophenone-3 concentrations in the United States: NHANES 2003–2006 and 2009–2012

    Energy Technology Data Exchange (ETDEWEB)

    Zamoiski, Rachel D., E-mail: rachel.zamoiski@nih.gov; Cahoon, Elizabeth K.; Michal Freedman, D.; Linet, Martha S.

    2015-10-15

    Background: Sunscreens protect against skin cancer and other harmful effects of solar ultraviolet radiation (UVR). Epidemiologic and public health surveys often rely on self-reported sunscreen use to estimate sun exposure and avoidance, but questions remain about the validity of self-reports. Benzophenone-3 (BP-3), a common sunscreen ingredient, can be detected in the urine. Prior studies suggest that BP-3 concentrations increase after application of sunscreen. Objectives: The goal of this study was to assess the validity of self-reported frequency of sunscreen use in relation to urinary BP-3 concentrations in a representative sample of the general US population, including in sub-groups defined by age, sex and race/ethnicity. Methods: To assess the relationship between categorical self-reported sunscreen use and creatinine-corrected urinary BP-3 concentrations, we conducted a linear regression adjusted for age, sex, race/ethnicity, six-month time period, body mass index, education, and sun avoidance behaviors. We tested for effect modification by age, sex, ethnicity and time period of measurement using multiplicative interaction terms and a F test. Results: BP-3 was positively associated with self-reported frequency of sunscreen use across all ages, sexes, race/ethnicities, and time periods. Crude and multivariate adjusted models were all statistically significant. R-square was relatively low for all models, ranging from 0.15 to 0.43. Conclusions: Urinary BP-3 is positively associated with self-reported frequency of sunscreen use in the general US population, even in groups with overall low sunscreen use. These results suggest that self-report is a valid, although weak, way of assessing relative frequencies of sunscreen usage in a population-based study. - Highlights: • Urinary benzophenone-3 (BP-3) is a metabolite of a common sunscreen ingredient. • We modeled urinary BP-3 against self-reported sunscreen usage. • We observed a positive association between

  1. Rare Earth Element Concentrations and Fractionation Patterns Along Groundwater Flow Paths in Two Different Aquifer Types (i.e., Sand vs. Carbonate)

    Science.gov (United States)

    Johannesson, K. H.; Tang, J.

    2003-12-01

    Groundwater samples were collected in two different types of aquifer (i.e., Carrizo Sand Aquifer, Texas and Upper Floridan carbonate Aquifer, west-central Florida) to study the concentrations, fractionation, and speciation of rare earth elements (REE) along groundwater flow paths in each aquifer. Major solutes and dissolved organic carbon (DOC) were also measured in these groundwaters. The Carrizo Sand aquifer was sampled in October 2002 and June 2003, whereas, to date, we have only sampled the Floridan once (i.e., June 2003). The data reveal no significant seasonal differences in major solute and REE concentrations for the Carrizo. In Carrizo sand aquifer, groundwaters from relatively shallow wells (i.e., less than 167 m) in the recharge zone are chiefly Ca-Na-HCO3-Cl type waters. With flow down-gradient the groundwaters shift composition to the Na-HCO3 waters. pH and alkalinity initially decrease with flow away from the recharge zone before increasing again down-gradient. DOC is generally low (0.65 mg/L) along the flow path. REE concentrations are highest in groundwaters from the recharge zone (Nd 40.5 pmol/kg), and decrease substantially with flow down-gradient reaching relatively low and stable values (Nd 4.1-8.6 pmol/kg) roughly 10 km from the recharge zone. Generally, Carrizo groundwaters exhibit HREE-enriched shale-normalized patterns. The HREE enrichments are especially strong for waters from the recharge zone [(Yb/Nd)SN =1.7-5.6], whereas down-gradient (deep) groundwaters have flatter patterns [(Yb/Nd)SN =0.7-2.5]. All groundwaters have slightly positive Eu anomalies (Eu/Eu* 0.09-0.14) and negative Ce anomalies (Ce/Ce* -0.85 - -0.07). In the Upper Floridan Aquifer, Ca, Mg, SO4, and Cl concentrations generally increase along groundwater flow path, whereas pH and alkalinity generally decrease. DOC is higher (0.64 - 2.29 mg/L) than in the Carrizo and initially increases along the flow path and then decreases down-gradient. LREE (Nd) concentrations generally

  2. Skeletal muscle fiber type composition and performance during repeated bouts of maximal, concentric contractions

    Science.gov (United States)

    Colliander, E. B.; Dudley, G. A.; Tesch, P. A.

    1988-01-01

    Force output and fatigue and recovery patterns were studied during intermittent short-term exercise. 27 men performed three bouts of 30 maximal unilateral knee extensions on 2 different occasions. Blood flow was maintained or occluded during recovery periods (60 s). Blood flow was restricted by inflating a pneumatic cuff placed around the proximal thigh. Muscle biopsies from vastus lateralis were analyzed for identification of fast twitch (FT) and slow twitch (ST) fibers and relative FT area. Peak torque decreased during each bout of exercise and more when blood flow was restricted during recovery. Initial peak torque (IPT) and average peak torque (APT) decreased over the three exercise bouts. This response was 3 fold greater without than with blood flow during recovery. IPT and APT decreased more in individuals with mainly FT fibers than in those with mainly ST fibers. It is suggested that performance during repeated bouts of maximal concentric contractions differs between individuals with different fiber type composition. Specifically, in high intensity, intermittent exercise with emphasis on anaerobic energy release a high FT composition may not necessarily be advantageous for performance.

  3. Concentration factors for fish

    International Nuclear Information System (INIS)

    Feldt, W.; Lauer, R.; Melzer, M.; Siebert, W.

    1978-01-01

    Concentration factors are defined as operators allowing to calculate the specific activity of fish meat from a given concentration of an element in the water. This parameter depends among others from the content of stable isotopes and homologues in the different waters. If this parameter is reasonably to be used for model calculations it must be referred to water with all of its content substances, these calculations also being based on this type of 'water'. (orig.) [de

  4. Estimation of surface-level PM2.5 concentration using aerosol optical thickness through aerosol type analysis method

    Science.gov (United States)

    Chen, Qi-Xiang; Yuan, Yuan; Huang, Xing; Jiang, Yan-Qiu; Tan, He-Ping

    2017-06-01

    Surface-level particulate matter is closely related to column aerosol optical thickness (AOT). Previous researches have successfully used column AOT and different meteorological parameters to estimate surface-level PM concentration. In this study, the performance of a selected linear model that estimates surface-level PM2.5 concentration was evaluated following the aerosol type analysis method (ATAM) for the first time. We utilized 443 daily average data for Xuzhou, Jiangsu province, collected using Aerosol Robotic Network (AERONET) during the period October 2013 to April 2016. Several parameters including atmospheric boundary layer height (BLH), relative humidity (RH), and effective radius of the aerosol size distribution (Ref) were used to assess the relationship between the column AOT and PM2.5 concentration. By including the BLH, ambient RH, and effective radius, the correlation (R2) increased from 0.084 to 0.250 at Xuzhou, and with the use of ATAM, the correlation increased further to 0.335. To compare the results, 450 daily average data for Beijing, pertaining to the same period, were utilized. The study found that model correlations improved by varying degrees in different seasons and at different sites following ATAM. The average urban industry (UI) aerosol ratios at Xuzhou and Beijing were 0.792 and 0.451, respectively, demonstrating poorer air conditions at Xuzhou. PM2.5 estimation at Xuzhou showed lower correlation (R2 = 0.335) compared to Beijing (R2 = 0.407), and the increase of R2 at Xuzhou and Beijing site following use of ATAM were 33.8% and 12.4%, respectively.

  5. Fundamentals and techniques of nonimaging optics for solar energy concentration. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Winston, R.

    1980-05-20

    Nonimaging optics is a new discipline with techniques, formalism and objectives quite distinct from the traditional methods of focusing optics. These new systems achieve or closely approach the maximum concentration permitted by the Second Law of Thermodynamics for a given angular acceptance and are often called ideal. Application of these new principles to solar energy over the past seven years has led to the invention of a new class of solar concentrators, the most well known version of which is the Compound Parabolic Concentrator or CPC. A new formalism for analyzing nonimaging systems in terms of a quantity called the geometrical vector flux has been developed. This has led not only to a better understanding of the properties of ideal concentrators but to the discovery of several new concentrator designs. One of these new designs referred to as the trumpet concentrator has several advantageous features when used as a secondary concentrator for a point focusing dish concentrator. A new concentrator solution for absorbers which must be separated from the reflector by a gap has been invented. The properties of a variety of new and previously known nonimaging optical configurations have been investigated: for example, Compound Elliptical Concentrators (CEC's) as secondary concentrators and asymmetric ideal concentrators. A thermodynamic model which explains quantitatively the enhancement of effective absorptance of gray body receivers through cavity effects has been developed. The classic method of Liu and Jordan, which allows one to predict the diffuse sunlight levels through correlation with the total and direct fraction was revised and updated and applied to predict the performance of nonimaging solar collectors. The conceptual design for an optimized solar collector which integrates the techniques of nonimaging concentration with evacuated tube collector technology was carried out.

  6. Medication errors: classification of seriousness, type, and of medications involved in the reports from a university teaching hospital

    Directory of Open Access Journals (Sweden)

    Gabriella Rejane dos Santos Dalmolin

    2013-12-01

    Full Text Available Medication errors can be frequent in hospitals; these errors are multidisciplinary and occur at various stages of the drug therapy. The present study evaluated the seriousness, the type and the drugs involved in medication errors reported at the Hospital de Clínicas de Porto Alegre. We analyzed written error reports for 2010-2011. The sample consisted of 165 reports. The errors identified were classified according to seriousness, type and pharmacological class. 114 reports were categorized as actual errors (medication errors and 51 reports were categorized as potential errors. There were more medication error reports in 2011 compared to 2010, but there was no significant change in the seriousness of the reports. The most common type of error was prescribing error (48.25%. Errors that occurred during the process of drug therapy sometimes generated additional medication errors. In 114 reports of medication errors identified, 122 drugs were cited. The reflection on medication errors, the possibility of harm resulting from these errors, and the methods for error identification and evaluation should include a broad perspective of the aspects involved in the occurrence of errors. Patient safety depends on the process of communication involving errors, on the proper recording of information, and on the monitoring itself.

  7. MEH-PPV and PCBM Solution Concentration Dependence of Inverted-Type Organic Solar Cells Based on Eosin-Y-Coated ZnO Nanorod Arrays

    Directory of Open Access Journals (Sweden)

    Riski Titian Ginting

    2013-01-01

    Full Text Available The influence of polymer solution concentration on the performance of chlorobenzene- (CB- and chloroform- (CF- based inverted-type organic solar cells has been investigated. The organic photoactive layers consisted of poly(2-methoxy-5-(2-ethyl hexyloxy-1,4-phenylenevinylene (MEH-PPV and (6,6-phenyl C61 butyric acid methyl ester (PCBM were spin coated from CF with concentrations of 4, 6, and 8 mg/mL and from CB with concentrations of 6, 8, and 10 mg/mL onto Eosin-Y-coated ZnO nanorod arrays (NRAs. Fluorine doped tin oxide (FTO and silver (Ag were used as electron collecting electrode and hole collecting electrode, respectively. Experimental results showed that the short circuit current density and power conversion efficiency increased with decrease of solution concentration for both CB and CF devices, which could be attributed to reducing charge recombination in thinner photoactive layer and larger contact area between the rougher photoactive layer and Ag contact. However, the open circuit voltage decreased with decreasing solution concentration due to increase of leakage current from ZnO NRAs to Ag as the ZnO NRAs were not fully covered by the polymer blend. The highest power conversion efficiencies of 0.54 ± 0.10% and 0.87 ± 0.15% were achieved at the respective lowest solution concentrations of CB and CF.

  8. Concentrated loads on concrete

    DEFF Research Database (Denmark)

    Lorenzen, Karen Grøndahl; Nielsen, Mogens Peter

    1997-01-01

    This report deals with concentrated loads on concrete.A new upper bound solution in the axisymmetrical case of a point load in the center of the end face of a cylinder is developed.Based on previous work dealing with failure mechanisms and upper bound solutions, new approximate formulas are devel......This report deals with concentrated loads on concrete.A new upper bound solution in the axisymmetrical case of a point load in the center of the end face of a cylinder is developed.Based on previous work dealing with failure mechanisms and upper bound solutions, new approximate formulas...

  9. Evaluation of Web-based Dietary Assessment Software for Children: comparing reported fruit, juice and vegetable intakes with plasma carotenoid concentration and school lunch observations

    DEFF Research Database (Denmark)

    Biltoft-Jensen, Anja Pia; Bysted, Anette; Trolle, Ellen

    2013-01-01

    Web-based Dietary Assessment Software for Children (WebDASC) was developed to estimate dietary intake in a school meal intervention study among 8- to 11-year-old Danish children. The present study validates self-reported fruit, juice and vegetable (FJV) intakes in 8- to 11-year-old children...... by comparing intake with plasma carotenoid concentration, and by comparing the reported FJV intake to actually eaten FJV, as observed by a photographic method. A total of eighty-one children, assisted by parents, reported their diet for seven consecutive days. For the same five schooldays as they reported...... their diet, the children's school lunch was photographed and weighed before and after eating. In the week after the diet reporting, fasting blood samples were taken. Self-reported intake of FJV and estimated intake of carotenoids were compared with plasma carotenoid concentration. Accuracy of self...

  10. Current Status of Concentrator Photovoltaic (CPV) Technology

    Energy Technology Data Exchange (ETDEWEB)

    Philipps, Simon P. [Fraunhofer Inst. for Solar Energy Systems ISE, Freiburg (Germany); Bett, Andreas W. [Fraunhofer Inst. for Solar Energy Systems ISE, Freiburg (Germany); Horowitz, Kelsey [National Renewable Energy Lab. (NREL), Golden, CO (United States); Kurtz, Sarah [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-12-01

    This report summarizes the status of the concentrator photovoltaic (CPV) market and industry as well as current trends in research and technology. This report is intended to guide research agendas for Fraunhofer ISE, the National Renewable Energy Laboratory (NREL), and other R&D organizations. Version 1.1 of this report includes recent progress in CPV. The recent record module efficiency of 38.9% at Concentrator Standard Test Conditions (CSTC) is an impressive result, demonstrating the continuing opportunity for CPV technology to improve. 38.9% at Concentrator Standard Test Conditions (CSTC) is an impressive result, demonstrating the continuing opportunity for CPV technology to improve. 38.9% at Concentrator Standard Test Conditions (CSTC) is an impressive result, demonstrating the continuing opportunity for CPV technology to improve. 38.9% at Concentrator Standard Test Conditions (CSTC) is an impressive result, demonstrating the continuing opportunity for CPV technology to improve.

  11. Nickel, Aluminum and Strontium Concentration in Different Samples of Egyptian Foodstuff

    International Nuclear Information System (INIS)

    Abu Khadra, S.A.; Abd El-Fattah, A.T.; Anwar, S.M.

    2003-01-01

    Eight different types of food items, collected from eight Egyptian governorates, were subjected to elemental analysis to determine Ni, Al, and Sr concentration by using Inductively Coupled Plasma-Atomic Emission Spectroscopy (ICP-AES). The result indicated that the concentration of Ni, Al and Sr are in range of 0.04-7.31, 0.07-5.56, 0.02-13.4 mg/kg-wet weight respectively. The maximum concentrations of Ni and Al are present in cereals and leafy vegetables while minimum values are present in roots and tubers. Sr concentration showed completely different trend. Its maximum value is present in fish samples. This focuses a very important remark about its active pathway (aquatic ecosystem) to prevent completely the disposal of radioactive Sr in any water body.By knowing the food consumption values by Egyptian, the daily dietary intake of these elements were calculated. The obtained mean values are 1.894, 2.242 and 1.483 mg/d/caput for Ni, Al and Sr respectively. These values are within the reported data and far away from their toxic intake level

  12. A case-control field study on the relationships among type 2 diabetes, sleepiness and habitual caffeine intake.

    Science.gov (United States)

    Urry, Emily; Jetter, Alexander; Holst, Sebastian C; Berger, Wolfgang; Spinas, Giatgen A; Langhans, Wolfgang; Landolt, Hans-Peter

    2017-02-01

    The purpose of this study was to examine the possible links between type 2 diabetes, daytime sleepiness, sleep quality and caffeine consumption. In this case-control field study, comparing type 2 diabetic ( n=134) and non-type 2 diabetic ( n=230) participants, subjects completed detailed and validated questionnaires to assess demographic status, health, daytime sleepiness, sleep quality and timing, diurnal preference, mistimed circadian rhythms and habitual caffeine intake. All participants gave saliva under standardised conditions for CYP1A2 genotyping and quantification of caffeine concentration. Hierarchical linear regression analyses examined whether type 2 diabetes status was associated with caffeine consumption. Type 2 diabetic participants reported greater daytime sleepiness ( p=0.001), a higher prevalence of sleep apnoea ( p=0.005) and napping ( p=0.008), and greater habitual caffeine intake ( pcaffeine concentration at bedtime ( p=0.01). Multiple regression analyses revealed that type 2 diabetes status was associated with higher self-reported caffeine consumption ( pcaffeine ( pcaffeine intake. Subjective sleep and circadian estimates were similar between case and control groups. Type 2 diabetic patients may self-medicate with caffeine to alleviate daytime sleepiness. High caffeine intake reflects a lifestyle factor that may be considered when promoting type 2 diabetes management.

  13. Comparing computing formulas for estimating concentration ratios

    International Nuclear Information System (INIS)

    Gilbert, R.O.; Simpson, J.C.

    1984-03-01

    This paper provides guidance on the choice of computing formulas (estimators) for estimating concentration ratios and other ratio-type measures of radionuclides and other environmental contaminant transfers between ecosystem components. Mathematical expressions for the expected value of three commonly used estimators (arithmetic mean of ratios, geometric mean of ratios, and the ratio of means) are obtained when the multivariate lognormal distribution is assumed. These expressions are used to explain why these estimators will not in general give the same estimate of the average concentration ratio. They illustrate that the magnitude of the discrepancies depends on the magnitude of measurement biases, and on the variances and correlations associated with spatial heterogeneity and measurement errors. This paper also reports on a computer simulation study that compares the accuracy of eight computing formulas for estimating a ratio relationship that is constant over time and/or space. Statistical models appropriate for both controlled spiking experiments and observational field studies for either normal or lognormal distributions are considered. 24 references, 15 figures, 7 tables

  14. 25 CFR 36.120 - What type of reporting is required to ensure accountability?

    Science.gov (United States)

    2010-04-01

    ... accountability? 36.120 Section 36.120 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION... SITUATIONS Homeliving Programs Waivers and Accountability § 36.120 What type of reporting is required to ensure accountability? The homeliving program must provide to the appropriate local school board or...

  15. Research and development of improved type radioactive waste volume reduction system

    International Nuclear Information System (INIS)

    Okamoto, Masahiro; Watanabe, Yoshifumi; Yamaoka, Katsuaki; Masaki, Tetsuo; Akagawa, Yoshihiro; Murakami, Tadashi; Miyake, Takashi.

    1985-01-01

    Development and research had been conducted since 1978 on an improved type radioactive waste volume reduction system incorporating calcining and incinerating fluidized bed type furnaces. This system can dispose of concentrated liquid wastes, combustible solid wastes, spent ion exchange resins and so forth by calcination or incineration to turn them into reduced-volume products. Recently a pilot test facility has constructed and tests has been conducted to demonstrate actual performance. Representative results of pilot tests are reported in this paper. (author)

  16. Development of compound parabolic concentrators for solar energy

    Energy Technology Data Exchange (ETDEWEB)

    O' Gallagher, J.; Winston, R.

    1983-10-01

    The compound parabolic concentrator (CPC) is not a specific collector, but a family of collectors based on a general design principle for maximizing the geometric concentration, C, for radiation within a given acceptance half angle = thetac. This maximum limit exceeds by a factor of 2 to 4 that attainable by systems using focussing optics. The wide acceptance angles permitted using these techniques have several unique advantages for solar concentrators including the elimination of the diurnal tracking requirement at intermediate concentrations (up to about 10x), collection of circumsolar and some diffuse radiation and relaxed tolerances. Because of these advantages, CPC type concentrators have applications in solar energy wherever concentration is desired, e.g., for a wide variety of both thermal and photovoltaic uses. The basic principles of nonimaging optical design are reviewed. Selected configurations for both non-evacuated and evacuated thermal collector applications are discussed with particular emphasis on the most recent advances. The use of CPC type elements as secondary concentrators is illustrated in the context of higher concentration photovoltaic applications.

  17. Mapping absolute tissue endogenous fluorophore concentrations with chemometric wide-field fluorescence microscopy

    Science.gov (United States)

    Xu, Zhang; Reilley, Michael; Li, Run; Xu, Min

    2017-06-01

    We report chemometric wide-field fluorescence microscopy for imaging the spatial distribution and concentration of endogenous fluorophores in thin tissue sections. Nonnegative factorization aided by spatial diversity is used to learn both the spectral signature and the spatial distribution of endogenous fluorophores from microscopic fluorescence color images obtained under broadband excitation and detection. The absolute concentration map of individual fluorophores is derived by comparing the fluorescence from "pure" fluorophores under the identical imaging condition following the identification of the fluorescence species by its spectral signature. This method is then demonstrated by characterizing the concentration map of endogenous fluorophores (including tryptophan, elastin, nicotinamide adenine dinucleotide, and flavin adenine dinucleotide) for lung tissue specimens. The absolute concentrations of these fluorophores are all found to decrease significantly from normal, perilesional, to cancerous (squamous cell carcinoma) tissue. Discriminating tissue types using the absolute fluorophore concentration is found to be significantly more accurate than that achievable with the relative fluorescence strength. Quantification of fluorophores in terms of the absolute concentration map is also advantageous in eliminating the uncertainties due to system responses or measurement details, yielding more biologically relevant data, and simplifying the assessment of competing imaging approaches.

  18. Maximum permissible concentrations and negligible concentrations for antifouling substances. Irgarol 1051, dichlofluanid, ziram, chlorothalonil and TCMTB

    NARCIS (Netherlands)

    Wezel AP van; Vlaardingen P van; CSR

    2001-01-01

    This report presents maximum permissible concentrations and negligible concentrations that have been derived for various antifouling substances used as substitutes for TBT. Included here are Irgarol 1051, dichlofluanide, ziram, chlorothalonil and TCMTB.

  19. Self-reported receipt of healthcare professional?s weight management counselling is associated with self-reported weight management behaviours of type 2 diabetes mellitus patients

    OpenAIRE

    Mogre, Victor; Wanaba, Peter; Apala, Peter; Nsoh, Jonas A.

    2016-01-01

    Background Weight loss has been shown to influence the health outcomes of type 2 diabetes patients. Providing weight management counselling to diabetes patients may help them adopt appropriate weight management behaviours to lose weight. This study determined the association between self-reported receipt of healthcare professional?s weight management counselling and the weight management behaviours of type 2 diabetes patients. Methods This cross-sectional study was conducted among 378 type 2 ...

  20. Urinary creatinine concentration is inversely related to glycaemic control and the presence of some diabetic complications in patients with newly diagnosed Type 2 diabetes

    DEFF Research Database (Denmark)

    Olivarius, Niels de Fine; Andreasen, Anne H; Vestbo, Else

    2006-01-01

    BACKGROUND: The ratio between urinary albumin concentration (UAC) and urinary creatinine concentration (UCC) is widely used to estimate renal involvement. We examined how UAC and UCC associate with each other, with other risk factors, and with diabetic complications in a population-based sample...... of Type 2 diabetic patients. METHODS: A freshly voided morning urine specimen was provided by 1,284 consecutive, newly diagnosed diabetic patients aged 40 years or over in general practice. Albumin was measured by a polyethyleneglycol radioimmunoassay and creatinine by a modified Jaffe method. RESULTS......: In a multivariate model including UAC, UCC, age, sex, HbA1c, and urinary glucose concentration, UAC increased with both age (P=.042) and HbA1c (P=.014), while UCC decreased (Phigh resting heart...

  1. Autoimmune polyendocrine syndrome type 1 – a case report from Bangladesh

    Directory of Open Access Journals (Sweden)

    Tahniyah Haq

    2016-01-01

    Full Text Available We describe a case of a 26 years old man who presented with adrenocortical insufficiency followed by hypoparathyroidism and subsequently mucocutaneous candidiasis. He also had nail dystrophy, cataract and alopecia, but no other endocrinopathies. He was diagnosed as a case of autoimmune polyendocrine syndrome type 1(APS 1. APS1 is a rare endocrine disorder and only a few cases have been reported from Bangladesh. IMC J Med Sci 2016; 10(1: 33-35

  2. Concurrent aggregation and transport of graphene oxide in saturated porous media: Roles of temperature, cation type, and electrolyte concentration.

    Science.gov (United States)

    Wang, Mei; Gao, Bin; Tang, Deshan; Yu, Congrong

    2018-04-01

    Simultaneous aggregation and retention of nanoparticles can occur during their transport in porous media. In this work, the concurrent aggregation and transport of GO in saturated porous media were investigated under the conditions of different combinations of temperature, cation type (valence), and electrolyte concentration. Increasing temperature (6-24 °C) at a relatively high electrolyte concentration (i.e., 50 mM for Na + , 1 mM for Ca 2+ , 1.75 mM for Mg 2+ , and 0.03 and 0.05 mM for Al 3+ ) resulted in enhanced GO retention in the porous media. For instance, when the temperature increased from 6 to 24 °C, GO recovery rate decreased from 31.08% to 6.53% for 0.03 mM Al 3+ and from 27.11% to 0 for 0.05 mM Al 3+ . At the same temperature, increasing cation valence and electrolyte concentration also promoted GO retention. Although GO aggregation occurred in the electrolytes during the transport, the deposition mechanisms of GO retention in the media depended on cation type (valence). For 50 mM Na + , surface deposition via secondary minima was the dominant GO retention mechanism. For multivalent cation electrolytes, GO aggregation was rapid and thus other mechanisms such as physical straining and sedimentation also played important roles in controlling GO retention in the media. After passing through the columns, the GO particles in the effluents showed better stability with lower initial aggregation rates. This was probably because less stable GO particles with lower surface charge densities in the porewater were filtered by the porous media, resulting in more stable GO particle with higher surface charge densities in the effluents. An advection-dispersion-reaction model was applied to simulate GO breakthrough curves and the simulations matched all the experimental data well. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. A postirradiation, myxoid type, malignant fibrous histiocytoma; A case report

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Masaki; Higuchi, Ryouhei; Ohsige, Kenji; Kouya, Michiko (Tokyo Metropolitan Fuchu Hospital, Tokyo (Japan)); Nozaki, Motohiro

    1993-09-01

    The authors discuss the case of a 59-year-old man who presented a mass in the dorsum of his right foot. He previously had had a hemangioma in this region from birth, and at the age of 10, radiation therapy had been administered to this region because of an ulcer that had developed. Additionally, so as to cover the ulcer, he had been given a free skin graft and a cross-leg flap. Some 50 years after this radiation, he noticed a mass in his foot, and a microscopic examination of a biopsied specimen of this mass revealed it to be a myxoid type, malignant fibrous histiocytoma (MFH). Thus, a below-the-knee amputation was performed. To the best of their knowledge, the authors report that 29 cases of an MFH developing after radiotherapy have been reported in the Japanese literature, and an analysis of these 29 cases is provided and the details of this case are given. (author).

  4. Primary intestinal lymphangiectasia as a component of autoimmune polyglandular syndrome type I: a report of 2 cases.

    Science.gov (United States)

    Makharia, Govind K; Tandon, Nikhil; Stephen, Neil de Jesus Rangel; Gupta, Siddhartha Datta; Tandon, Rakesh K

    2007-01-01

    Chronic diarrhea and steatorrhea occur frequently in patients with autoimmune polyglandular syndrome (APS) type I. Intestinal lymphangiectasia has been reported earlier as a cause of steatorrhea in a young girl with APS Type I. We describe 2 patients with APS Type I who were found to have intestinal lymphangiectasia, one of whom had symptomatic protein-losing enteropathy.

  5. New insights into the extraction of invisible gold in a low-grade high-sulfur Carlin-type gold concentrate by bio-pretreatment

    Science.gov (United States)

    Qiu, Xiao-bin; Wen, Jian-kang; Huang, Song-tao; Yang, Hong-ying; Liu, Mei-lin; Wu, Biao

    2017-10-01

    To extract gold from a low-grade (13.43 g/t) and high-sulfur (39.94wt% sulfide sulfur) Carlin-type gold concentrate from the Nibao deposit, Guizhou, a bio-pretreatment followed by carbon-in-pulp (CIP) cyanide leaching process was used. Various methods were used to detect the low-grade gold in the concentrate; however, only time-of-flight secondary-ion mass spectrometry (TOF-SIMS) was successful. With bio-pretreatment, the gold recovery rate increased by approximately 70.16% compared with that obtained by direct cyanide leaching of the concentrate. Various attempts were made to increase the final gold recovery rate. However, approximately 20wt% of the gold was non-extractable. To determine the nature of this non-extractable gold, mineralogy liberation analysis (MLA), formation of secondary product during the bio-pretreatment, and the preg-robbing capacity of the carbonaceous matter in the ore were investigated. The results indicated that at least four factors affected the gold recovery rate: gold occurrence, tight junctions of gold-bearing pyrite with gangue minerals, jarosite coating of the ore, and the carbonaceous matter content.

  6. Influence of counting chamber type on CASA outcomes of equine semen analysis.

    Science.gov (United States)

    Hoogewijs, M K; de Vliegher, S P; Govaere, J L; de Schauwer, C; de Kruif, A; van Soom, A

    2012-09-01

    Sperm motility is considered to be one of the key features of semen analysis. Assessment of motility is frequently performed using computer-assisted sperm analysis (CASA). Nevertheless, no uniform standards are present to analyse a semen sample using CASA. We hypothesised that the type of counting chamber used might influence the results of analysis and aimed to study the effect of chamber type on estimated concentration and motility of an equine semen sample assessed using CASA. Commonly used disposable Leja chambers of different depths were compared with disposable and reusable ISAS chambers, a Makler chamber and a World Health Organization (WHO) motility slide. Motility parameters and concentrations obtained with CASA using these different chambers were analysed. The NucleoCounter was used as gold standard for determining concentration. Concentration and motility parameters were significantly influenced by the chamber type used. Using the NucleoCounter as the gold standard for determining concentration, the correlation coefficients were low for all of the various chambers evaluated, with the exception of the 12 µm deep Leja chamber. Filling a chamber by capillary forces resulted in a lower observed concentration and reduced motility parameters. All chambers evaluated in this study resulted in significant lower progressive motility than the WHO prepared slide, with the exception of the Makler chamber, which resulted in a slight, but statistically significant, increase in progressive motility estimates. Computer-assisted sperm analysis can only provide a rough estimate of sperm concentration and overestimation is likely when drop-filled slides with a coverslip are used. Motility estimates using CASA are highly influenced by the counting chamber; therefore, a complete description of the chamber type used should be provided in semen reports and in scientific articles. © 2011 EVJ Ltd.

  7. Airborne protein concentration: a key metric for type 1 allergy risk assessment-in home measurement challenges and considerations.

    Science.gov (United States)

    Tulum, Liz; Deag, Zoë; Brown, Matthew; Furniss, Annette; Meech, Lynn; Lalljie, Anja; Cochrane, Stella

    2018-01-01

    Exposure to airborne proteins can be associated with the development of immediate, IgE-mediated respiratory allergies, with genetic, epigenetic and environmental factors also playing a role in determining the likelihood that sensitisation will be induced. The main objective of this study was to determine whether airborne concentrations of selected common aeroallergens could be quantified in the air of homes using easily deployable, commercially available equipment and analytical methods, at low levels relevant to risk assessment of the potential to develop respiratory allergies. Additionally, air and dust sampling were compared and the influence of factors such as different filter types on allergen quantification explored. Low volume air sampling pumps and DUSTREAM ® dust samplers were used to sample 20 homes and allergen levels were quantified using a MARIA ® immunoassay. It proved possible to detect a range of common aeroallergens in the home with sufficient sensitivity to quantify airborne concentrations in ranges relevant to risk assessment (Limits of Detection of 0.005-0.03 ng/m 3 ). The methodology discriminates between homes related to pet ownership and there were clear advantages to sampling air over dust which are described in this paper. Furthermore, in an adsorption-extraction study, PTFE (polytetrafluoroethylene) filters gave higher and more consistent recovery values than glass fibre (grade A) filters for the range of aeroallergens studied. Very low airborne concentrations of allergenic proteins in home settings can be successfully quantified using commercially available pumps and immunoassays. Considering the greater relevance of air sampling to human exposure of the respiratory tract and its other advantages, wider use of standardised, sensitive techniques to measure low airborne protein concentrations and how they influence development of allergic sensitisation and symptoms could accelerate our understanding of human dose-response relationships

  8. Nonimaging concentrators for solar thermal energy

    Science.gov (United States)

    Winston, R.; Gallagher, J. J.

    1980-03-01

    A small experimental solar collector test facility was used to explore applications of nonimaging optics for solar thermal concentration in three substantially different configurations: a single stage system with moderate concentration on an evacuated absorber (a 5.25X evacuated tube Compound Parabolic Concentrator or CPC), a two stage system with high concentration and a non-evacuated absorber (a 16X Fresnel lens/CPC type mirror) and moderate concentration single stage systems with non-evacuated absorbers for lower temperature (a 3X and a 6.5X CPC). Prototypes of each of these systems were designed, built and tested. The performance characteristics are presented.

  9. Foodborne botulinum type E intoxication associated with dried bean curd: first case report in Taiwan.

    Science.gov (United States)

    Lai, Lung-Shiang; Wang, Yi-Mei; Lin, Chin-Hsien

    2011-06-01

    Botulism type E intoxication is a rare condition among human botulism. We aim to describe a first case of botulism type E intoxication in Taiwan. We report a 36-year-old young man with foodborne botulism type E associated with commercially vacuum packaged dried bean curd. He developed bilateral ptosis, diplopia and dysphagia 4 days after taking the dried bean curd. Electrophysiologic findings demonstrated waxing responses to 3 Hz repetitive nerve stimulation and decreased compound muscle action potentials on peripheral nerve conduction study. A bioassay for botulism in mice demonstrated that the patient had botulism caused by type E botulinum toxin. Antibodeis to C. botulinum type E were identified from his serum, confirming the diagnosis. This is the first known case of foodborne type E botulism in Taiwan. The potential source of this foodborne botulism should consider contaminated food made of soy beans.

  10. Concentration of Endogenous Secretory Receptor for Advanced Glycation End Products and Matrix Gla Protein in Controlled and Uncontrolled Type 2 Diabetes Mellitus Patients

    Directory of Open Access Journals (Sweden)

    Dwi Yuniati Daulay

    2013-04-01

    Full Text Available BACKGROUND: Advanced glycation end products (AGE and their receptor (RAGE system play an important role in the development of diabetic vascular complications. Recently, an endogenous secretory RAGE (esRAGE has been identified as a novel splice variant, which lacks the transmembrane domain and is secreted in human sera. Interestingly, it was reported that esRAGE binds AGE ligands and neutralizes AGE actions. Many studies have reported that diabetes mellitus correlates with vascular calcification event and increases progressively in uncontrolled diabetes. Matrix Gla Protein (MGP is known to act as an inhibitor in vascular calcification. The aim of this study was to observe progress of vascular calcification in uncontrolled diabetes patient by biochemical markers MGP as inhibitor in vascular calcification, via mechanism of AGEs. METHODS: This study was an observational study with cross sectional design on adult type 2 diabetic male patients who were defined by the 2011 Indonesian diabetes mellitus consensus criteria. RESULTS: The results of this study showed that there was a positive significant correlation between esRAGE and HbA1C (r=0.651, p=0.009, and negative correlation between MGP and HbA1C (r=-0.465, p=0.081 in controlled diabetes group. In uncontrolled diabetes group there was a positive significant correlation between MGP and HbA1C (r=0.350, p=0.023, despite the fact esRAGE showed no significant correlation with HbA1C. There was no significant difference in level of esRAGE and MGP in controlled and uncontrolled diabetes group, but MGP showed lower level in uncontrolled diabetes group, contrary to esRAGE that had higher concentration. CONCLUSIONS: In diabetes condition, complications of vascular calcification are caused by the mechanism of increased AGE formation represented by esRAGE. In diabetes control it is very important to keep the blood vessels from complications caused by vascular calcification. KEYWORDS: type 2 diabetes mellitus

  11. Controlled production of Camembert-type cheeses. Part II. Changes in the concentration of the more volatile compounds.

    Science.gov (United States)

    Leclercq-Perlat, Marie-Noëlle; Latrille, Eric; Corrieu, Georges; Spinnler, Henry-Eric

    2004-08-01

    Flavour generation in cheese is a major aspect of ripening. In order to enhance aromatic qualities it is necessary to better understand the chemical and microbiological changes. Experimental Camembert-type cheeses were prepared in duplicate from pasteurized milk inoculated with Kluyveromyces lactis, Geotrichum candidum, Penicillium camemberti and Brevibacterium linens under aseptic conditions. Two replicates performed under controlled conditions of temperature (12 degrees C), relative humidity (95 +/- 2%), and atmosphere showed similar ripening characteristics. The evolutions of metabolite concentrations were studied during ripening. The volatile components were extracted by dynamic headspace extraction, separated and quantified by gas chromatography and identified by mass spectrometry. For each cheese the volatile concentrations varied with the part considered (rind or core). Except for ethyl acetate and 2-pentanone, the volatile quantities observed were higher than their perception thresholds. The flavour component production was best correlated with the starter strains. During the first 10 days the ester formations (ethyl, butyl and isoamyl acetates) were associated with the concentrations of K. lactis and G. candidum. The rind quantity of esters was lower than that observed in core probably due to (1) a diffusion from the core to the surface and (2) evaporation from the surface to the chamber atmosphere. G. candidum and Brev. linens association produced 3 methyl butanol and methyl 3-butanal from leucine, respectively. DMDS came from the methionine catabolism due to Brev. linens. Styrene production was attributed to Pen. camemberti. 2-Pentanone evolution was associated with Pen. camemberti spores and G. candidum. 2-Heptanone changes were not directly related to flora activities while 2-octanone production was essentially due to G. candidum. This study also demonstrates the determining role of volatile component diffusion.

  12. Effect of temperature and ionic impurities at very low concentrations on stress corrosion cracking of type 304 stainless steel

    Energy Technology Data Exchange (ETDEWEB)

    Ruther, W.E.; Soppet, W.K.; Kassner, T.F.

    1984-11-01

    The relative effect of approx. 12 anion species, in conjunction with hydrogen and sodium cations, on the stress-corrosion-cracking (SCC) behavior of lightly sensitized Type 304 stainless steel was investigated in constant-extension-rate-tensile (CERT) tests at 289/sup 0/C in water with 0.2 ppM dissolved oxygen at total conductivity values of less than or equal to 1 ..mu..S/cm. The results show that the sulfur species, either in acid or sodium form, produce the highest degree of IGSCC relative to other anions. The effect of temperature on the SCC behavior of the material was investigated in CERT tests over the range 110 to 320/sup 0/C in high-purity water and in water containing 0.1 and 1.0 ppM sulfate as H/sub 2/SO/sub 4/ at a dissolved oxygen concentration of 0.2 ppM. The CERT parameters were correlated with impurity concentration (i.e., conductivity) and the electrochemical potential of platinum and Type 304 stainless steel electrodes in the high-temperature environments. Maximum IGSCC occurred at temperatures between approx. 200 and 250/sup 0/C in high-purity water, and the addition of sulfate increased the average crack growth rates and the temperature range over which maximum susceptibility occurred. A distinct transition from intergranular to transgranular and ultimately to a ductile failure mode was observed as the temperature increased from approx. 270 to 320/sup 0/C in high-purity water. This transition was attributed to a decrease in the open-circuit corrosion potential of the steel below a critical value of approx. 0 mV(SHE) at the higher temperature. A large decrease in the crack growth rates of fracture-mechanics-type specimens of the steel was also found when the temperature was increased from 289 to 320/sup 0/C in high-purity water with 0.2 ppM dissolved oxygen. 26 references, 8 figures, 6 tables.

  13. Effect of temperature and ionic impurities at very low concentrations on stress corrosion cracking of type 304 stainless steel

    International Nuclear Information System (INIS)

    Ruther, W.E.; Soppet, W.K.; Kassner, T.F.

    1984-11-01

    The relative effect of approx. 12 anion species, in conjunction with hydrogen and sodium cations, on the stress-corrosion-cracking (SCC) behavior of lightly sensitized Type 304 stainless steel was investigated in constant-extension-rate-tensile (CERT) tests at 289 0 C in water with 0.2 ppM dissolved oxygen at total conductivity values of less than or equal to 1 μS/cm. The results show that the sulfur species, either in acid or sodium form, produce the highest degree of IGSCC relative to other anions. The effect of temperature on the SCC behavior of the material was investigated in CERT tests over the range 110 to 320 0 C in high-purity water and in water containing 0.1 and 1.0 ppM sulfate as H 2 SO 4 at a dissolved oxygen concentration of 0.2 ppM. The CERT parameters were correlated with impurity concentration (i.e., conductivity) and the electrochemical potential of platinum and Type 304 stainless steel electrodes in the high-temperature environments. Maximum IGSCC occurred at temperatures between approx. 200 and 250 0 C in high-purity water, and the addition of sulfate increased the average crack growth rates and the temperature range over which maximum susceptibility occurred. A distinct transition from intergranular to transgranular and ultimately to a ductile failure mode was observed as the temperature increased from approx. 270 to 320 0 C in high-purity water. This transition was attributed to a decrease in the open-circuit corrosion potential of the steel below a critical value of approx. 0 mV(SHE) at the higher temperature. A large decrease in the crack growth rates of fracture-mechanics-type specimens of the steel was also found when the temperature was increased from 289 to 320 0 C in high-purity water with 0.2 ppM dissolved oxygen. 26 references, 8 figures, 6 tables

  14. Development of electret technology to measure indoor radon-daughter concentrations: Final report (Phase 1)

    International Nuclear Information System (INIS)

    Kotrappa, P.; Dempsey, J.C.; Stieff, L.R.

    1989-05-01

    A new type of radon progeny monitor called an electret radon progeny integrating sampling unit (E-RPISU) was developed and demonstrated which uses an electret ion chamber to measure the progeny concentration. A conventional 1 LPM particulate air sampling system is used to collect the progeny on a 35 cm 2 filter which is mounted on the side of the electret ion chamber such that the collected progeny are exposed to the inside of the chamber. The alpha radiation emitted by the progeny collected on the filter ionizes the air in the 220 ml chamber. The ions of opposite polarity collect on the surface of the 127 μm thick electret and reduce its surface voltage. A specially built surface voltmeter is used to measure the electret voltage before and after sampling. The electret voltage drop which occurs during the sampling period is shown to be proportional to the time integrated progeny concentration. Two prototype systems were fabricated and tested in homes and in calibrated radon chambers. The resulting data are presented and analyzed. The calibration factor for the E-RPISU ranged from 1.5 to 2.0 V/mWL-day depending on the electret voltage. Two of the E-RPISUs were delivered to UNC Geotech for further testing. 32 refs., 11 figs., 5 tabs

  15. Reporting diet-related health issues through newspapers: portrayal of cardiovascular disease and Type 2 diabetes.

    Science.gov (United States)

    Hellyer, Nicole Elizabeth; Haddock-Fraser, Janet

    2011-02-01

    This study identifies (i) the extent to which newsprint media communicate to their readers the lifestyle factors associated with the development of cardiovascular disease and Type 2 diabetes and (ii) newspaper portrayal of social determinants affecting onset of disease. A content analysis of five leading UK national newspapers and their Sunday equivalents was conducted over a 3-month period between January and March 2008. This study shows that cardiovascular disease had much higher press interest than Type 2 diabetes. 'Middle-market' and 'Quality' papers had higher levels of reporting than the 'Popular' press, but the patterns were more complex when the comprehensiveness of reporting was measured within each article. Social determinants affecting disease onset were poorly reported by newspapers, supporting similar research conducted in other countries. This research identifies that there is potential for newspapers to improve their reporting of lifestyle diseases, by including individual and social determinants of disease onset. Lower social classes who read the popular press receive the lowest frequency of reporting and could benefit most from this information. While the research identifies that newspapers are missing the potential to actively communicate and reinforce government health policy, it recognises that the commercial context of the print media may counter such behaviour.

  16. Pseudo (Platelet-type von Willebrand disease in pregnancy: a case report

    Directory of Open Access Journals (Sweden)

    Grover Neetu

    2013-01-01

    Full Text Available Abstract Background Pseudo (platelet-type-von Willebrand disease is a rare autosomal dominant bleeding disorder caused by an abnormal function of the glycoprotein lb protein; the receptor for von Willebrand factor. This leads to an increased removal of VWF multimers from the circulation as well as platelets and this results in a bleeding diathesis. Worldwide, less than 50 patients are reported with platelet type von Willebrand disease (PT-VWD. Case presentation We describe the management of platelet type von Willebrand disease in pregnancy of a 26 year old Caucasian primigravida. The initial diagnosis was made earlier following a significant haemorrhage post tonsillectomy several years prior to pregnancy. The patient was managed under a multidisciplinary team which included obstetricians, haematologists, anaesthetists and neonatologists. Care plans were made for the ante- natal, intra-partum and post-partum periods in partnership with the patient. The patient’s platelet count levels dropped significantly during the antenatal period. This necessitated the active exclusion of other causes of thrombocytopenia in pregnancy. A vaginal delivery was desired and plans were made for induction of labour at 38 weeks of gestation with platelet cover in view of the progressive fall of the platelet count. The patient however went into spontaneous labour on the day of induction. She was transfused two units of platelets before delivery. She had an unassisted vaginal delivery of a healthy baby. The successful antenatal counselling has encouraged the diagnosis of the same condition in her mother and sister. We found this to be a particularly interesting case as well as challenging to manage due to its rarity. Psuedo von Willebrand disease in pregnancy can be confused with a number of other differential diagnoses, such as gestational thrombocutopenia, idiopathatic thrombocytopenia, thrombotic thrombocytopenic purpura and pre-eclampsia; all need consideration

  17. Ovicidal activity of different concentrations of Pochonia chlamydosporia chlamydospores on Taenia taeniaeformis eggs.

    Science.gov (United States)

    Braga, F R; Silva, A R; Carvalho, R O; Araújo, J V; Pinto, P S A

    2011-03-01

    Three concentrations of chlamydospores of the nematophagous fungus Pochonia chlamydosporia (1000, 10,000 and 20,000 per Petri dish) were evaluated in vitro on Taenia taeniaeformis eggs. Chlamydospores at each concentration were cultured in two different media: 2% water-agar (2%WA) and 2% corn-meal-agar (2%CMA). Taenia taeniaeformis eggs were plated in each chlamydospore concentration in 2%WA and 2%CMA (treated groups) and without fungus (control group). Eggs were removed from each Petri dish at intervals of 7, 14 and 21 days and classified according to ovicidal activity (type 1, type 2 and type 3 effects). Plates containing 2%CMA showed the highest percentages for type 3 effect (81.3%) on the 21st day of observation. A difference (P < 0.01) between the media 2%WA and 2%CMA for type 1 effect was observed only at a concentration of 1000 chlamydospores on the 7th day. There were differences (P < 0.01) between 2%WA and 2%CMA on the 14th and 21st days, at the concentration of 20,000 chlamydospores, for type 1 and type 3 effects. Regression curves for type 3 effect in 2%WA and 2%CMA at the tested concentrations showed higher ovicidal activity with increasing chlamydospore concentrations. Results indicate that, at concentrations of 1000, 10,000 and 20,000 per Petri dish, chlamydospores of P. chlamydosporia effectively destroyed T. taeniaeformis eggs and can be considered a potential biological control agent for this cestode.

  18. Mercury and cadmium concentrations in milk in Puerto Rico

    International Nuclear Information System (INIS)

    Chellapan, S.; Pedersen, K.B.; Plaza, H.

    1976-01-01

    Milk was collected over a four-month period from three representative sectors of Puerto Rico. Instrumental neutron activation analysis (INAA) performed on the samples showed that the mercury concentration was slightly higher than safe upper limit set by the World Health Organization on food products. The values reported here for mercury concentrations are very similar to those found for dairy products in the Toronto area of Canada in 1970, but considerably higher than some reported from the United States in 1964. Mean cadmium concentrations were found to be higher than the values reported in the literature. Some variations in cadmium concentrations were observed areawide as well as a function of time. MURTHY et al reported the cadmium concentration in milk to be 0.018 to 0.03 ppm in the United States in the year 1967; this is about one sixth of the concentrations found in this study for Puerto Rico. In addition to INAA atomic absorption photospectrometry was used on a smaller number of samples to verify the concentration levels of cadmium. For this determination nine milk samples and two blanks were analyzed. The concentrations were found to vary between 0.01 and 0.06 ppm. These values are in better agreement with the values reported for the United States than are the ones obtained from using INAA; however, their spread is much greater. (T.G.)

  19. Special audit report on the Department of Energy`s Arms and military-type equipment

    Energy Technology Data Exchange (ETDEWEB)

    Layton, J.C.

    1996-02-01

    Based on the activities associated with the recent recovery of the eight armored personnel carriers, a review was conducted of the Department`s controls over arms and military-type equipment in its possession. The objects were to determine whether (1) the quantity of arms and military-type equipment on hand was justified by mission needs, (2) inventory listings of arms were accurate, (3) property disposals were properly controlled and executed, and (4) loans and borrowed equipment were appropriate and accounted for accurately. The purpose of this report is to summarize the most significant issues identified and point out where the Department needs stronger controls over its inventory of arms and military-type property.

  20. MIXED HYALINE VASCULAR AND PLASMA CELL TYPE CASTLEMAN’S DISEASE: REPORT OF A CASE

    Directory of Open Access Journals (Sweden)

    F. Asgarani

    2006-05-01

    Full Text Available Castleman’s disease (angiofollicular lymphoid hyperplasia includes a heterogeneous group of lymphoproliferative disorders. The cause of this disease remains uncertain. There are two types of localized Castleman’s disease: the more common hyaline vascular and the plasma cell types. Mixed variant is an uncommon localized lesion in general population. The lesions can occur in any part of the body that contains lymphoid tissue, although seventy percent are found in the anterior mediastinum. We report a thirty years old boy with Castleman’s disease who presented with fever, anorexia, weight loss,sweating, anemia and abdominal mass. The histologic examination of the biopsy specimens revealed a mixed hyaline vascular and plasma cell type of Castleman’s disease.

  1. High-efficiency concentrator silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Sinton, R.A.; Cuevas, A.; King, R.R.; Swanson, R.M. (Stanford Univ., CA (USA). Solid-State Electronics Lab.)

    1990-11-01

    This report presents results from extensive process development in high-efficiency Si solar cells. An advanced design for a 1.56-cm{sup 2} cell with front grids achieved 26% efficiency at 90 suns. This is especially significant since this cell does not require a prismatic cover glass. New designs for simplified backside-contact solar cells were advanced from a status of near-nonfunctionality to demonstrated 21--22% for one-sun cells in sizes up to 37.5 cm{sup 2}. An efficiency of 26% was achieved for similar 0.64-cm{sup 2} concentrator cells at 150 suns. More fundamental work on dopant-diffused regions is also presented here. The recombination vs. various process and physical parameters was studied in detail for boron and phosphorous diffusions. Emitter-design studies based solidly upon these new data indicate the performance vs design parameters for a variety of the cases of most interest to solar cell designers. Extractions of p-type bandgap narrowing and the surface recombination for p- and n-type regions from these studies have a generality that extends beyond solar cells into basic device modeling. 68 refs., 50 figs.

  2. Case report of novel CACNA1A gene mutation causing episodic ataxia type 2

    Directory of Open Access Journals (Sweden)

    David Alan Isaacs

    2017-05-01

    Full Text Available Background: Episodic ataxia type 2 (OMIM 108500 is an autosomal dominant channelopathy characterized by paroxysms of ataxia, vertigo, nausea, and other neurologic symptoms. More than 50 mutations of the CACNA1A gene have been discovered in families with episodic ataxia type 2, although 30%–50% of all patients with typical episodic ataxia type 2 phenotype have no detectable mutation of the CACNA1A gene. Case: A 46-year-old Caucasian man, with a long history of bouts of imbalance, vertigo, and nausea, presented to our hospital with 2 weeks of ataxia and headache. Subsequent evaluation revealed a novel mutation in the CACNA1A gene: c.1364 G > A Arg455Gln. Acetazolamide was initiated with symptomatic improvement. Conclusion: This case report expands the list of known CACNA1A mutations associated with episodic ataxia type 2.

  3. Effect of neutron irradiation on p-type silicon

    International Nuclear Information System (INIS)

    Sopko, B.

    1973-01-01

    The possibilities are discussed of silicon isotope reactions with neutrons of all energies. In the reactions, 30 Si is converted to a stable phosphorus isotope forming n-type impurities in silicon. The above reactions proceed as a result of thermal neutron irradiation. An experiment is reported involving irradiation of two p-type silicon single crystals having a specific resistance of 2000 ohm.cm and 5000 to 20 000 ohm.cm, respectively, which changed as a result of irradiation into n-type silicon with a given specific resistance. The specific resistance may be pre-calculated from the concentration of impurities and the time of irradiation. The effects of irradiation on other silicon parameters and thus on the suitability of silicon for the manufacture of semiconductor elements are discussed. (J.K.)

  4. An electro-active paper actuator made with cellulose–polypyrrole–ionic liquid nanocomposite: influence of ionic liquid concentration, type of anion and humidity

    International Nuclear Information System (INIS)

    Mahadeva, Suresha K; Kim, Jaehwan

    2010-01-01

    This paper reports a cellulose–polypyrrole–ionic liquid (CPIL) nanocomposite that can produce large actuating displacement in a low humidity environment. The fabrication process and actuator performance of the CPIL nanocomposite actuator are illustrated. Experimental results revealed that the size of anion, concentration of ionic liquid and ambient humidity level have a significant influence on the actuator performance of the CPIL nanocomposite. The bending displacement of the CPIL nanocomposite actuator was enhanced with increasing anion size, ionic liquid concentration and humidity level. CPIL nanocomposite made with 4% BMIBF 4 ionic liquid exhibited a very large bending displacement with excellent durability under ambient conditions (30% relative humidity and 25 °C). This is probably the first report that cellulose based electro-active paper actuator can exhibit such a large bending displacement under ambient conditions. Experimental results revealed that the proposed CPIL nanocomposite actuator under study can be operated up to 70% humidity level

  5. Nonimaging solar concentrator with uniform irradiance

    Science.gov (United States)

    Winston, Roland; O'Gallagher, Joseph J.; Gee, Randy C.

    2004-09-01

    We report results of a study our group has undertaken under NREL/DOE auspices to design a solar concentrator with uniform irradiance on a planar target. This attribute is especially important for photovoltaic concentrators.

  6. Effect of type of concentrated sweet cream buttermilk on the manufacture, yield, and functionality of pizza cheese.

    Science.gov (United States)

    Govindasamy-Lucey, S; Lin, T; Jaeggi, J J; Martinelli, C J; Johnson, M E; Lucey, J A

    2007-06-01

    Sweet cream buttermilk (SCB) is a rich source of phospholipids (PL). Most SCB is sold in a concentrated form. This study was conducted to determine if different concentration processes could affect the behavior of SCB as an ingredient in cheese. Sweet cream buttermilk was concentrated by 3 methods: cold ( pizza cheese was manufactured using the 3 different types of concentrated SCB as an ingredient in standardized milk. Cheesemilks of casein:fat ratio of 1.0 and final casein content approximately 2.7% were obtained by blending ultrafiltered (UF)-SCB retentate (19.9% solids), RO-SCB retentate (21.9% solids), or EVAP-SCB retentate (36.6% solids) with partially skimmed milk (11.2% solids) and cream (34.6% fat). Control milk (11.0% solids) was standardized by blending partially skimmed milk with cream. Cheese functionality was assessed using dynamic low-amplitude oscillatory rheology, UW Meltprofiler (degree of flow after heating to 60 degrees C), and performance of cheese on pizza. Initial trials with SCB-fortified cheeses resulted in approximately 4 to 5% higher moisture (51 to 52%) than control cheese (approximately 47%). In subsequent trials, procedures were altered to obtain similar moisture content in all cheeses. Fat recoveries were significantly lower in RO- and EVAP-SCB cheeses than in control or UF-SCB cheeses. Nitrogen recoveries were not significantly different but tended to be slightly lower in control cheeses than the various SCB cheeses. Total PL recovered in SCB cheeses ( approximately 32 to 36%) were lower than control ( approximately 41%), even though SCB is high in PL. From the rheology test, the loss tangent curves at temperatures > 40 degrees C increased as cheese aged up to a month and were significantly lower in SCB cheeses than the control, indicating lower meltability. Degree of flow in all the cheeses was similar regardless of the treatment used, and as cheese ripened, it increased for all cheeses. Trichloroacetic acid-soluble N levels were

  7. Serum anti-Müllerian hormone concentration in women with polycystic ovary syndrome and type 1 diabetes mellitus.

    Science.gov (United States)

    Łebkowska, Agnieszka; Adamska, Agnieszka; Karczewska-Kupczewska, Monika; Nikołajuk, Agnieszka; Otziomek, Elżbieta; Milewski, Robert; Górska, Maria; Wołczyński, Sławomir; Kowalska, Irina

    2016-05-01

    A single prior study conducted in Chilean women has shown that women with type 1 diabetes mellitus (T1DM) and polycystic ovary syndrome (PCOS) have a normal serum anti-Müllerian hormone (AMH) concentrations despite polycystic ovarian morphology. As it is not clear why women with PCOS+T1DM would not have an elevated concentrations of AMH, we hypothesize that women with T1DM and PCOS have a similar hormonal profile and serum AMH levels as is observed in classic PCOS. We studied 89 women: 37 with T1DM (16 with PCOS+T1DM, 21 with T1DM/no-PCOS), 36 with PCOS (PCOS) and 16 healthy women (control group) matched for age and body mass index (BMI). A clinical examination, determination of serum AMH and sex hormones, and an ultrasonographic evaluation of the ovaries were performed for all study participants. Serum AMH concentrations were significantly higher in women with PCOS+T1DM than in those with T1DM/no-PCOS (p<0.001) and was not different between both PCOS groups (PCOS vs PCOS+T1DM). Ovarian volume and ovarian follicle count did not differ between women with PCOS+T1DM and PCOS. The number of ovarian follicles was higher in patients with PCOS+T1DM and PCOS versus the control (p=0.007, p<0.001) and versus cases of T1DM/no-PCOS (p<0.001, p<0.001, respectively). Cross-sectionally, AMH concentrations correlated positively with luteinizing hormone (LH) (r=0.4; p<0.001), testosterone (r=0.2, p=0.02), ovarian volume (r=0.4, p<0.001) and follicle count (r=0.7, p<0.001). In both groups, PCOS+T1DM and PCOS, AMH was related to LH (r=0.5; p=0.036; r=0.3; p=0.031) and to ovarian follicle number (r=0.7; p<0.001; r=0.4; p=0.006). In multivariate logistic regression analysis, serum AMH was the only predictor of PCOS in T1DM women (OR=1.73; 95% CI 1.07-2.79, p=0.023). Women with T1DM and PCOS have a similar hormonal profile and serum AMH concentrations as observed in classic PCOS. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Final Report on the Operation and Maintenance Improvement Program for Concentrating Solar Power Plants

    International Nuclear Information System (INIS)

    Cohen, Gilbert E.; Kearney, David W.; Kolb, Gregory J.

    1999-01-01

    This report describes the results of a six-year, $6.3 million project to reduce operation and maintenance (O ampersand M) costs at power plants employing concentrating solar power (CSP) technology. Sandia National Laboratories teamed with KJC Operating Company to implement the O ampersand M Improvement Program. O ampersand M technologies developed during the course of the program were demonstrated at the 150-MW Kramer Junction solar power park located in Boron, California. Improvements were made in the following areas: (a) efficiency of solar energy collection, (b) O ampersand M information management, (c) reliability of solar field flow loop hardware, (d) plant operating strategy, and (e) cost reduction associated with environmental issues. A 37% reduction in annual O ampersand M costs was achieved. Based on the lessons learned, an optimum solar- field O ampersand M plan for future CSP plants is presented. Parabolic trough solar technology is employed at Kramer Junction. However, many of the O ampersand M improvements described in the report are also applicable to CSP plants based on solar power tower or dish/engine concepts

  9. Final Report on the Operation and Maintenance Improvement Program for Concentrating Solar Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Cohen Gilbert E.; Kearney, David W.; Kolb, Gregory J.

    1999-06-01

    This report describes the results of a six-year, $6.3 million project to reduce operation and maintenance (O&M) costs at power plants employing concentrating solar power (CSP) technology. Sandia National Laboratories teamed with KJC Operating Company to implement the O&M Improvement Program. O&M technologies developed during the course of the program were demonstrated at the 150-MW Kramer Junction solar power park located in Boron, California. Improvements were made in the following areas: (a) efficiency of solar energy collection, (b) O&M information management, (c) reliability of solar field flow loop hardware, (d) plant operating strategy, and (e) cost reduction associated with environmental issues. A 37% reduction in annual O&M costs was achieved. Based on the lessons learned, an optimum solar- field O&M plan for future CSP plants is presented. Parabolic trough solar technology is employed at Kramer Junction. However, many of the O&M improvements described in the report are also applicable to CSP plants based on solar power tower or dish/engine concepts.

  10. Environmental isotope data no. 10: World survey of isotope concentration in precipitation (1988-1991). Report from a network

    International Nuclear Information System (INIS)

    1994-01-01

    This is the tenth volume of the publication Environmental Isotope Data: World Survey of Isotope Concentration in Precipitation. This volume is primarily concerned with the concentration of the environmental isotopes (tritium, deuterium and oxygen-18) in monthly samples of precipitation taken by a global network of 169 stations in the period 1988 to 1991. Selected meteorological data, such as the amount of precipitation, mean water vapour pressure and surface air temperature, are also presented. Data before 1988 which were unavailable at the time of the earlier issues have also been included in the latter part of this volume as late reports. The data are being widely used in hydrological, hydrometeorological and climatological studies. 9 refs, 2 figs

  11. Instability predictions for circumferentially cracked Type-304 stainless-steel pipes under dynamic loading. Final report

    International Nuclear Information System (INIS)

    Zahoor, A.; Wilkowski, G.; Abou-Sayed, I.; Marschall, C.; Broek, D.; Sampath, S.; Rhee, H.; Ahmad, J.

    1982-04-01

    This report provides methods to predict margins of safety for circumferentially cracked Type 304 stainless steel pipes subjected to applied bending loads. An integrated combination of experimentation and analysis research was pursued. Two types of experiments were performed: (1) laboratory-scale tests on center-cracked panels and bend specimens to establish the basic mechanical and fracture properties of Type 304 stainless steel, and (2) full-scale pipe fracture tests under quasi-static and dynamic loadings to assess the analysis procedures. Analyses were based upon the simple plastic collapse criterion, a J-estimation procedure, and elastic-plastic large-deformation finite element models

  12. Effect of reflection losses on stationary dielectric-filled nonimaging concentrators

    Science.gov (United States)

    Madala, Srikanth; Boehm, Robert F.

    2016-10-01

    The effect of Fresnel reflection and total internal reflection (TIR) losses on the performance parameters in refractive solar concentrators has often been downplayed because most refractive solar concentrators are traditionally the imaging type, yielding a line or point image on the absorber surface when solely interacted with paraxial etendue ensured by solar tracking. Whereas, with refractive-type nonimaging solar concentrators that achieve two-dimensional (rectangular strip) focus or three-dimensional (circular or elliptical) focus through interaction with both paraxial and nonparaxial etendue within the acceptance angle, the Fresnel reflection and TIR losses are significant as they will affect the performance parameters and, thereby, energy collection. A raytracing analysis has been carried out to illustrate the effects of Fresnel reflection and TIR losses on four different types of stationary dielectric-filled nonimaging concentrators, namely V-trough, compound parabolic concentrator, compound elliptical concentrator, and compound hyperbolic concentrator. The refractive index (RI) of a dielectric fill material determines the acceptance angle of a solid nonimaging collector. Larger refractive indices yield larger acceptance angles and, thereby, larger energy collection. However, they also increase the Fresnel reflection losses. This paper also assesses the relative benefit of increasing RI from an energy collection standpoint.

  13. Plasma extracellular superoxide dismutase concentration, allelic variations in the SOD3 gene and risk of myocardial infarction and all-cause mortality in people with type 1 and type 2 diabetes.

    Science.gov (United States)

    Mohammedi, Kamel; Bellili-Muñoz, Naïma; Marklund, Stefan L; Driss, Fathi; Le Nagard, Hervé; Patente, Thiago A; Fumeron, Frédéric; Roussel, Ronan; Hadjadj, Samy; Marre, Michel; Velho, Gilberto

    2015-01-15

    Oxidative stress is involved in development of diabetes complications. Extracellular superoxide dismutase (EC-SOD, SOD3) is a major extracellular antioxidant enzyme and is highly expressed in arterial walls. Advanced oxidation protein products (AOPP) and 8-iso-prostaglandin (isoprostane) are markers of oxidative stress. We investigated association of SOD3 gene variants, plasma concentrations of EC-SOD, AOPP and isoprostane with myocardial infarction and mortality in diabetic patients. We studied three cohorts designed to evaluate the vascular complications of diabetes: the GENEDIAB study (469 participants with type 1 diabetes at baseline; follow-up data for 259 participants), the GENESIS study (603 participants with type 1 diabetes at baseline; follow-up data for 525 participants) and the DIABHYCAR study (3137 participants with type 2 diabetes at baseline and follow-up). Duration of follow-up was 9, 5, and 5 years, respectively. Main outcome measures were incidence of myocardial infarction, and cardiovascular and total mortality during follow-up. Six single nucleotide polymorphisms in the SOD3 locus were genotyped in the three cohorts. Plasma concentrations of EC-SOD, AOPP, and isoprostane were measured in baseline samples of GENEDIAB participants. In GENEDIAB/GENESIS pooled cohorts, the minor T-allele of rs2284659 variant was inversely associated with the prevalence at baseline (Odds Ratio 0.48, 95% CI 0.29-0.78, p = 0.004) and the incidence during follow-up of myocardial infarction (Hazard Ratio 0.58, 95% CI 0.40-0.83, p = 0.003) and with cardiovascular (HR 0.33, 95% CI 0.08-0.74, p = 0.004) and all-cause mortality (HR 0.44, 95% CI 0.21-0.73, p = 0.0006). The protective allele was associated with higher plasma EC-SOD and lower plasma AOPP concentrations in GENEDIAB. It was also inversely associated with incidence of myocardial infarction (HR 0.75, 95% CI 0.59-0.94, p = 0.01) and all-cause mortality (HR 0.87, 95% CI 0.79-0.97, p = 0

  14. Analytic validation and comparison of three commercial immunoassays for measurement of plasma atrial/A-type natriuretic peptide concentration in horses

    DEFF Research Database (Denmark)

    Trachsel, D S; Schwarzwald, C C; Grenacher, B

    2014-01-01

    Measurement of atrial/A-type natriuretic peptide (ANP) concentrations may be of use for assessment of cardiac disease, and reliable data on the analytic performance of available assays are needed. To assess the suitability for clinical use of commercially available ANP assays, intra-assay and inter......-Altman analyses. For all assays, precision was moderate but acceptable and dilution parallelism was good. All assays showed analytic performance similar to other immunoassays used in veterinary medicine. However, the results from the three assays were poorly comparable. Our study highlights the need...

  15. Error identification, disclosure, and reporting: practice patterns of three emergency medicine provider types.

    Science.gov (United States)

    Hobgood, Cherri; Xie, Jipan; Weiner, Bryan; Hooker, James

    2004-02-01

    To gather preliminary data on how the three major types of emergency medicine (EM) providers, physicians, nurses (RNs), and out-of-hospital personnel (EMTs), differ in error identification, disclosure, and reporting. A convenience sample of emergency department (ED) providers completed a brief survey designed to evaluate error frequency, disclosure, and reporting practices as well as error-based discussion and educational activities. One hundred sixteen subjects participated: 41 EMTs (35%), 33 RNs (28%), and 42 physicians (36%). Forty-five percent of EMTs, 56% of RNs, and 21% of physicians identified no clinical errors during the preceding year. When errors were identified, physicians learned of them via dialogue with RNs (58%), patients (13%), pharmacy (35%), and attending physicians (35%). For known errors, all providers were equally unlikely to inform the team caring for the patient. Disclosure to patients was limited and varied by provider type (19% EMTs, 23% RNs, and 74% physicians). Disclosure education was rare, with error to a patient. Error discussions are widespread, with all providers indicating they discussed their own as well as the errors of others. This study suggests that error identification, disclosure, and reporting challenge all members of the ED care delivery team. Provider-specific education and enhanced teamwork training will be required to further the transformation of the ED into a high-reliability organization.

  16. Impurity Resonant States p-type Doping in Wide-Band-Gap Nitrides

    Science.gov (United States)

    Liu, Zhiqiang; Yi, Xiaoyan; Yu, Zhiguo; Yuan, Gongdong; Liu, Yang; Wang, Junxi; Li, Jinmin; Lu, Na; Ferguson, Ian; Zhang, Yong

    2016-01-01

    In this work, a new strategy for achieving efficient p-type doping in high bandgap nitride semiconductors to overcome the fundamental issue of high activation energy has been proposed and investigated theoretically, and demonstrated experimentally. Specifically, in an AlxGa1-xN/GaN superlattice structure, by modulation doping of Mg in the AlxGa1-xN barriers, high concentration of holes are generated throughout the material. A hole concentration as high as 1.1 × 1018 cm-3 has been achieved, which is about one order of magnitude higher than that typically achievable by direct doping GaN. Results from first-principle calculations indicate that the coupling and hybridization between Mg 2p impurity and the host N 2p orbitals are main reasons for the generation of resonant states in the GaN wells, which further results in the high hole concentration. We expect this approach to be equally applicable for other high bandgap materials where efficient p-type doing is difficult. Furthermore, a two-carrier-species Hall-effect model is proposed to delineate and discriminate the characteristics of the bulk and 2D hole, which usually coexist in superlattice-like doping systems. The model reported here can also be used to explain the abnormal freeze-in effect observed in many previous reports.

  17. New method of design of nonimaging concentrators.

    Science.gov (United States)

    Miñano, J C; González, J C

    1992-06-01

    A new method of designing nonimaging concentrators is presented and two new types of concentrators are developed. The first is an aspheric lens, and the second is a lens-mirror combination. A ray tracing of three-dimensional concentrators (with rotational symmetry) is also done, showing that the lens-mirror combination has a total transmission as high as that of the full compound parabolic concentrators, while their depth is much smaller than the classical parabolic mirror-nonimaging concentrator combinations. Another important feature of this concentrator is that the optically active surfaces are not in contact with the receiver, as occurs in other nonimaging concentrators in which the rim of the mirror coincides with the rim of the receiver.

  18. Calibration of cellulose nitrate film for measurement of time-integrated concentration of radon-222 in air

    International Nuclear Information System (INIS)

    Jha, G.; Raghavayya, M.

    1986-01-01

    Measurement of time-integrated concentration of 222 Rn in air by using solid-state nuclear track detectors (SSNTD) is finding increasing application in such diverse fields as radiation protection, exploration of radioactive minerals, prediction of earthquakes etc. While there are several types of SSNTDs sensitive to specific types of particulate radiation, films made from cellulose nitrate (CN) are found to be the best suited for quick and quantitative measurement of alpha radiation. This is because CN films are available in small thicknesses, of the order of 10-12 μm, which can be suitably evaluated by spark counting technique. This report describes the use of a sensitive thin film of CN (Kodak LR 115, Type II) for quantitative estimation of 222 Rn. The film (along with the base is exposed in a cylindrical plastic cup closed at one end with a special rubber membrane which permits discrimination of 222 Rn against 220 Rn, which is also present in air to varying extents. The calibration procedure, including etching and evaluation of track registration efficiency, are described in detail. The mean track registration efficiency works out to 41.9 per cent and the sensitivity of the system is found to be 58.92 tracks cm -2 per (Bq.litre -1 ) day. The report lists the advantages and limitations of the system for measurement of time-integrated concentration of 222 Rn in air. (author)

  19. Quantified Hole Concentration in AlGaN Nanowires for High-Performance Ultraviolet Emitters

    KAUST Repository

    Zhao, Chao; Ebaid, Mohamed; Zhang, Huafan; Priante, Davide; Janjua, Bilal; Zhang, Daliang; Wei, Nini; Alhamoud, Abdullah; Shakfa, M. Khaled; Ng, Tien Khee; Ooi, Boon S.

    2018-01-01

    P-type doping in wide bandgap and new classes of ultra-wide bandgap materials has long been a scientific and engineering problem. The challenges arise from the large activation energy of dopants and high densities of dislocations in materials. We report here, a significantly enhanced p-type conduction using high-quality AlGaN nanowires. For the first time, the hole concentration in Mg-doped AlGaN nanowires is quantified. The incorporation of Mg into AlGaN was verified by correlation with photoluminescence and Raman measurements. The open-circuit potential measurements further confirmed the p-type conductivity; while Mott-Schottky experiments measured a hole concentration of 1.3×1019 cm-3. These results from photoelectrochemical measurements allow us to design prototype ultraviolet (UV) light-emitting diodes (LEDs) incorporating the AlGaN quantum-disks-in-nanowire and optimized p-type AlGaN contact layer for UV-transparency. The ~335-nm LEDs exhibited a low turn-on voltage of 5 V with a series resistance of 32 Ω, due to the efficient p-type doping of the AlGaN nanowires. The bias-dependent Raman measurements further revealed the negligible self-heating of devices. This study provides an attractive solution to evaluate electrical properties of AlGaN, which is applicable to other wide bandgap nanostructures. Our results are expected to open doors to new applications for wide and ultra-wide bandgap materials.

  20. Quantified Hole Concentration in AlGaN Nanowires for High-Performance Ultraviolet Emitters

    KAUST Repository

    Zhao, Chao

    2018-05-29

    P-type doping in wide bandgap and new classes of ultra-wide bandgap materials has long been a scientific and engineering problem. The challenges arise from the large activation energy of dopants and high densities of dislocations in materials. We report here, a significantly enhanced p-type conduction using high-quality AlGaN nanowires. For the first time, the hole concentration in Mg-doped AlGaN nanowires is quantified. The incorporation of Mg into AlGaN was verified by correlation with photoluminescence and Raman measurements. The open-circuit potential measurements further confirmed the p-type conductivity; while Mott-Schottky experiments measured a hole concentration of 1.3×1019 cm-3. These results from photoelectrochemical measurements allow us to design prototype ultraviolet (UV) light-emitting diodes (LEDs) incorporating the AlGaN quantum-disks-in-nanowire and optimized p-type AlGaN contact layer for UV-transparency. The ~335-nm LEDs exhibited a low turn-on voltage of 5 V with a series resistance of 32 Ω, due to the efficient p-type doping of the AlGaN nanowires. The bias-dependent Raman measurements further revealed the negligible self-heating of devices. This study provides an attractive solution to evaluate electrical properties of AlGaN, which is applicable to other wide bandgap nanostructures. Our results are expected to open doors to new applications for wide and ultra-wide bandgap materials.

  1. Aluminium and Aroma Compound Concentration in Beer During Storage at Different Temperatures

    Directory of Open Access Journals (Sweden)

    Marija Soldo Gjeldum

    2006-01-01

    Full Text Available Problem of aluminium in beer has been elaborated in several papers over the last decade. However, the effect of aluminium on organoleptic properties of beer has been observed in few papers where it has been stated that aluminium gives beer a »metallic« and bitter flavour without any observations on particular aroma compound changes. Also, the number of reports on precise changes of aroma components throughout different storage conditions is surprisingly scarce. In order to investigate the changes of aluminium concentration along with aroma compound changes, graphite furnace-atomic absorption spectrophotometry (GF-AAS with Zeeman background correction and gas chromatography with static headspace sampler (GC-HSS were used in this work. Analyses were conducted periodically throughout seven months of storage on three different brands of beer from name breweries. Samples were taken before and after filling in aluminium cans. One part of samples was stored in a refrigerator (4 °C and the other in a thermostatic chamber (22 °C. The effects of beer brand and storage conditions on aluminium concentration and level of aroma compounds were measured. To prove the effect of aluminium concentration on the changes of aroma compounds, the adequate level of aluminium sulphate was added to bottled beer samples stored at 28 °C. Although different beer types showed significantly different aluminium concentration, it could be the result of other factors (different batches of identical beer type showed significantly different aluminium concentration as well. Samples that were stored in the refrigerator were protected from aluminium migration from the can to the beer and showed increased aroma stability. Level of aroma constituents of analyzed beer brands was significantly different. Elevated aluminium concentration did not have any noticeable effect on the level of aroma compounds in beer samples stored at 28 °C.

  2. Measurements and statistical analyses of indoor radon concentrations in Tokyo and surrounding areas

    International Nuclear Information System (INIS)

    Sugiura, Shiroharu; Suzuki, Takashi; Inokoshi, Yukio

    1995-01-01

    Since the UNSCEAR report published in 1982, radiation exposure to the respiratory tract due to radon and its progeny has been regarded as the single largest contributor to the natural radiation exposure of the general public. In Japan, the measurement of radon gas concentrations in many types of buildings have been surveyed by national and private institutes. We also carried out the measurement of radon gas concentrations in different types of residential buildings in Tokyo and its adjoining prefectures from October 1988 to September 1991, to evaluate the potential radiation risk of the people living there. One or two simplified passive radon monitors were set up in each of the 34 residential buildings located in the above-mentioned area for an exposure period of 3 months each. Comparing the average concentrations in the buildings of different materials and structures, those in the concrete steel buildings were always higher than those in the wooden and the prefabricated mortared buildings. The radon concentrations were proved to become higher in autumn and winter, and lower in spring and summer. Radon concentrations in an underground room of a concrete steel building showed the highest value throughout our investigation, and statistically significant seasonal variation was detected by the X-11 method developed by the U.S. Bureau of Census. The values measured in a room at the first floor of the same concrete steel building also showed seasonal variation, but the phase of variation was different. Another multivariate analysis suggested that the building material and structure are the most important factors concerning the levels of radon concentration among other factors such as the age of the building and the use of ventilators. (author)

  3. Diffuse Type Primary Mycobacterium Tuberculosis of the Breast: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun A; Kang, Bong Joo; Kim, Sung Hun; Kim, Hnana; Lee, Ah Won [Seoul St. Mary' s Hospital, The Catholic University of Korea, Seoul (Korea, Republic of)

    2011-12-15

    Tuberculous mastitis is a rare manifestation of mycobacterium tuberculosis infection. It mimics inflammatory breast cancer or other pyogenic inflammations. In most of the tuberculous mastitis reports, coexisting or prior tuberculosis infection and secondary infection of the breast by direct spread via axillary or cervical lymphadenopathy, or hematogenous spread have been noted. We describe the mammographic and ultrasonographic findings of a case of diffuse type mycobacterium tuberculosis of the breast showing diffuse edema which was confirmed as tuberculosis through biopsy and had no evidence of old or concurrent pulmonary tuberculosis on chest computed tomography

  4. Handheld Multi-Gas Meters Market Survey Report

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Gustavious [Brigham Young Univ., Provo, UT (United States); Wald-Hopkins, Mark David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Obrey, Stephen J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Akhadov, Valida Dushdurova [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-23

    Handheld multi-gas meters (MGMs) are equipped with sensors to monitor oxygen (O2) levels and additional sensors to detect the presence of combustible or toxic gases in the environment. This report is limited to operational response-type MGMs that include at least four different sensors. These sensors can vary by type and by the chemical monitored. In real time, the sensors report the concentration of monitored gases in the atmosphere near the MGM. To provide emergency responders with information on handheld multi-gas meters, the System Assessment and Validation for Emergency Responders (SAVER) Program conducted a market survey. This market survey report is based on information gathered between November 2015 and February 2016 from vendors, Internet research, industry publications, an emergency responder focus group, and a government issued Request for Information (RFI) that was posted on the Federal Business Opportunities website.

  5. Design and construction of non-imaging planar concentrator for concentrator photovoltaic system

    Energy Technology Data Exchange (ETDEWEB)

    Chong, K.K.; Siaw, F.L.; Wong, C.W.; Wong, G.S. [Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Off Jalan Genting Kelang, Setapak, 53300 Kuala Lumpur, Wilayah Persekutuan (Malaysia)

    2009-05-15

    A novel configuration of solar concentrator, which is the non-imaging planar concentrator, capable of producing much more uniform sunlight and reasonably high concentration ratio, is designed and constructed. This design is envisioned to be incorporated in concentrator photovoltaic (CPV) systems. The work presented here reports on the design, optical alignment and application of the prototype, which is installed at Universiti Tunku Abdul Rahman (UTAR), Malaysia. In the architecture of the prototype, 360 flat mirrors, each with a dimension of 4.0 cm x 4.0 cm, are arranged into 24 rows and 15 columns with a total reflection area of about 5760 cm{sup 2}. In addition to that, illumination distribution for the prototype is simulated and its results are then compared with the experiment result. (author)

  6. Variations in exhaled nitric oxide concentration after three types of dives

    NARCIS (Netherlands)

    van Ooij, Pieter-Jan; Houtkooper, Antoinette; van Hulst, Rob

    2010-01-01

    An increase in exhaled nitric oxide concentration (FENO) occurs during an exacerbation of chronic obstructive lung disease or other inflammatory processes of the airway. Raised FENO levels are also observed during normobaric, mild hyperoxic exposures, whereas after hyperbaric hyperoxic exposure the

  7. Balo`s concentric sclerosis; value of magnetic resonance imaging in diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Singh, S.; Kuruvilla, A.; Korah, I.P. [Christian Medical College and Hospital, Vellore, Tamilnadu, (India). Department of Radiodiagnosis; Alexander, M. [Christian Medical College and Hospital, Vellore, Tamilnadu, (India). Department of Neurosciences

    1999-08-01

    We report two cases of Balo`s concentric sclerosis that demonstrate the typical magnetic resonance imaging (MRI) findings of concentric rings of demyelination involving the superficial and deep white matter and sparing the cortex. In both cases biopsy was not performed as MRI findings and multi-mode evoked potential studies were consistent with demyelinating illness. The theories regarding the pathogenesis of this peculiar appearance are briefly reviewed. Balo`s concentric sclerosis is a very rare type of demyelinating disease characterized pathologically by large alternating lamellae of demyelinated and myelinated white matter arranged in a concentric pattern. This progressive disease is more often found in young male adults and is more common in the Philippines. Balo`s concentric sclerosis is considered an unusual variant of multiple sclerosis (MS); however, some authors believe it to be a different entity. Although the pathogenesis of the concentric sclerosis is debated, the cause of demyelination is generally presumed to be the same as that of multiple sclerosis. There is striking resemblance between the magnetic resonance (MR) appearance and the histopathological features of MS. Not all cases may show a typical MR appearance. Prior to MR imaging, most of them were diagnosed at post-mortem. To our knowledge, few cases have been diagnosed by MR imaging in life. Copyright (1999) Blackwell Science Pty Ltd 15 refs., 2 figs.

  8. Relationship between Sucralose Consumption and Serum Concentration of Glycosylated Hemoglobin in People with Type 2 Diabetes Mellitus without Complications

    Directory of Open Access Journals (Sweden)

    María del Carmen Cortés-López

    2017-11-01

    Full Text Available People who live with diabetes consume sucralose to control their blood glucose, but there is a controversy about this topic. To evaluate the relationship between sucralose consumption and serum concentration of glycosylated hemoglobin in people with Type 2 Diabetes Mellitus without complications. Cross-sectional study. Universe of 27 214 people with Type 2 Diabetes Mellitus without complications, users of a primary care unit from the Instituto Mexicano del Seguro Social in the state of Jalisco, Mexico. Simple probabilistic sample, n = 194 (p = 0,05. Propositive sampling. Selection criteria: adults of any gender and education level who agreed to participate. Variables: sociodemographic, anthropometric, clinical and dietary. Data collection instruments: Sociodemographic questionnaire, Tanita Fitscan© 585 scale, Tanita Fitscan© HR-200 stadiometer, Body Flex© tape-measure, Slim Guide© plicometer, Afinion© AS100 analyzer, and Frequency of Food Consumption Questionnaire. Information sources: clinical files and Mexican System of Equivalent Foods. Analysis: descriptive and inferential statistics (p ≤ 0,05. 194 people. Mean age 60,23 ± 11,16, interval 28-93 years. 56,2% females and 43,8% males. Difference between glycosilated hemoglobin means: sucralose consumers 7,5% ± 1,7%, no sucralose consumers 8,1% ± 2,1% (p < 0,01. Association force “sucralose consumption/high glycosilated hemoglobin concentration” OR = 1,42 (CI95% 0,63, 3,21. Lineal correlation “quarterly sucralose consumption/serum concentration of glycosylated hemoglobin” ρ = -0,754 (R2 = 0,0057, p = 0,333. This results were partially consistent to the pre-existing literature. Studies with representative stratified samples and control of dietary variables are required for better results.

  9. The potential effect of technology and distractions on undergraduate students' concentration.

    Science.gov (United States)

    Attia, Najya A; Baig, Lubna; Marzouk, Yousef I; Khan, Anwar

    2017-01-01

    In the present era, it is difficult to keep the concentration of college students at its maximum potential during the class time, as there are many distractions that negatively impact students' concentration and prevent optimal learning. Technologies such as laptops and cell phones have invaded the classroom, raising considerable concerns about their effects on college students' attention in the classroom. Despite these concerns, no research has been done in Saudi Arabia on the effects of technology and other types of classroom distractions on students' concentration. In the current study, we have attempted to identify students' perceptions of major distractions in the classroom based on seventeen internally (self-produced) and twenty-four externally produced classroom situations. The students participating in this study rated the degree to which each distraction interferes with their concentration on the class materials and their ability to learn. Data were collected through surveys of 265 students (66 and 199 students from medical and basic classes, respectively), including 97 females and 168 males 17-23 years of age from the academic years 2010 to 2014. A validated self-administered questionnaire was handed to the students in the classroom. The students were asked to report and rate the classroom distraction produced by 24 external internal distracters (Table-II), on a 5-point scale. The results revealed that ringing cell phones in the class were the most commonly reported electronic external distractor for 68% of students, and 21% of them reported being extremely distracted by this noise. Having an instructor who is difficult to understand was the most commonly reported external behavioral distractor for 75% of students, and 48% of them rated this as extremely distracting. Students talking in class were the most self-produced distractor for 72% of students; negatively impacting their concentration and ability to learn, and 42% of them rated it as an extreme

  10. Type 1 diabetes mellitus, coeliac disease, and lymphoma: a report of four cases.

    LENUS (Irish Health Repository)

    O'Connor, T M

    2012-02-03

    INTRODUCTION: Patients with Type 1 diabetes mellitus have a high prevalence of coeliac disease, symptoms of which are often mild, atypical, or absent. Untreated coeliac disease is associated with an increased risk of malignancy, particularly of lymphoma. We describe four patients with Type 1 diabetes mellitus and coeliac disease who developed lymphoma. CASE REPORTS: Two patients were male and two female. In three patients, coeliac disease and lymphoma were diagnosed simultaneously. Enteropathy-associated T cell lymphoma occurred in two patients, Hodgkin\\'s disease in one, and B cell lymphoma in one. Response to treatment was in general poor, and three patients died soon after the diagnosis of lymphoma was made. CONCLUSION: As the relative risk of lymphoma is reduced by a gluten-free diet, a high index of suspicion for coeliac disease should exist in all Type 1 diabetic patients with unexplained constitutional or gastrointestinal symptoms.

  11. Glass wool filters for concentrating waterborne viruses and agricultural zoonotic pathogens

    Science.gov (United States)

    Millen, Hana T.; Gonnering, Jordan C.; Berg, Ryan K.; Spencer, Susan K.; Jokela, William E.; Pearce, John M.; Borchardt, Jackson S.; Borchardt, Mark A.

    2012-01-01

    The key first step in evaluating pathogen levels in suspected contaminated water is concentration. Concentration methods tend to be specific for a particular pathogen group, for example US Environmental Protection Agency Method 1623 for Giardia and Cryptosporidium1, which means multiple methods are required if the sampling program is targeting more than one pathogen group. Another drawback of current methods is the equipment can be complicated and expensive, for example the VIRADEL method with the 1MDS cartridge filter for concentrating viruses2. In this article we describe how to construct glass wool filters for concentrating waterborne pathogens. After filter elution, the concentrate is amenable to a second concentration step, such as centrifugation, followed by pathogen detection and enumeration by cultural or molecular methods. The filters have several advantages. Construction is easy and the filters can be built to any size for meeting specific sampling requirements. The filter parts are inexpensive, making it possible to collect a large number of samples without severely impacting a project budget. Large sample volumes (100s to 1,000s L) can be concentrated depending on the rate of clogging from sample turbidity. The filters are highly portable and with minimal equipment, such as a pump and flow meter, they can be implemented in the field for sampling finished drinking water, surface water, groundwater, and agricultural runoff. Lastly, glass wool filtration is effective for concentrating a variety of pathogen types so only one method is necessary. Here we report on filter effectiveness in concentrating waterborne human enterovirus, Salmonella enterica, Cryptosporidium parvum, and avian influenza virus.

  12. Effects of concentrated sunlight on organic photovoltaics

    DEFF Research Database (Denmark)

    Tromholt, Thomas; Katz, Eugene A.; Hirsch, Baruch

    2010-01-01

    We report the effects of concentrated sunlight on key photovoltaic parameters and stability of organic photovoltaics (OPV). Sunlight collected and concentrated outdoors was focused into an optical fiber and delivered onto a 1 cm2 bulk-heterojunction cell. Sunlight concentration C was varied gradu...

  13. Low serum cartonectin/CTRP3 concentrations in newly diagnosed type 2 diabetes mellitus: in vivo regulation of cartonectin by glucose.

    Directory of Open Access Journals (Sweden)

    Bo Ban

    Full Text Available OBJECTIVES: Cartonectin is a novel adipokine of the C1q complement/TNF-related protein (CTRP superfamily, with glucose lowering effects, anti-inflammatory and cardio-protective properties. We sought to investigate circulating cartonectin concentrations in subjects with type 2 diabetes mellitus (T2DM as well as age and BMI matched control subjects. We also examined the effects of a 2 hour 75 g oral glucose tolerance test (OGTT on serum cartonectin concentrations in T2DM subjects. DESIGN: Cross-sectional study [newly diagnosed (first discovery, not on any treatments T2DM (n = 47 and control (n = 63 subjects]. Serum cartonectin was measured by ELISA. RESULTS: Serum cartonectin concentrations were significantly lower in patients with T2DM compared to controls (P0.05. There were no significant correlations in T2DM subjects (n = 47. In control subjects (n = 63, serum cartonectin was significantly negatively correlated with CRP, and significantly positively correlated with insulin, HOMA-IR and leptin. However, when subjected to multiple regression analysis, none of these variables were predictive of serum cartonectin (P>0.05. Finally, serum cartonectin concentrations were significantly lower in T2DM subjects after a 2 hour 75 g OGTT (P<0.01. CONCLUSIONS: Cartonectin may serve as a novel biomarker for the prediction and early diagnosis of T2DM patients. Furthermore, cartonectin and/or pharmacological agents that increase circulating cartonectin levels can represent a new therapeutic field in the treatment of T2DM patients. Further research is needed to clarify these points.

  14. A high concentration of prorenin in early pregnancy is associated with development of pre-eclampsia in women with type 1 diabetes

    DEFF Research Database (Denmark)

    Ringholm, L; Pedersen-Bjergaard, U; Thorsteinsson, B

    2011-01-01

    consecutive pregnant women with type 1 diabetes (median duration 16 years [range 1-36 years], HbA(1c) 6.6% [range 4.9-10.5%]) in early pregnancy. At 8, 14, 21, 27 and 33 weeks and once within 5 days postpartum, blood was sampled for measurements of prorenin, renin, angiotensinogen, ACE and SSAO. HbA(1c...... 4.4 [95% CI 1.5-13.0], p¿=¿0.007), i.e. an increase of prorenin of 100 ng angiotensin I ml(-1) h(-1) implies a 4.4 times higher risk of subsequent pre-eclampsia. CONCLUSIONS/INTERPRETATION: In type 1 diabetic women with pre-eclampsia, a higher concentration of prorenin in early pregnancy and higher......AIMS/HYPOTHESIS: The aim of this study was to investigate whether components of the renin-angiotensin system and semicarbazide-sensitive amine oxidase (SSAO) are associated with the development of pre-eclampsia in women with type 1 diabetes. METHODS: This was an observational study of 107...

  15. Recurrent spontaneous hip dislocation in a patient with neurofibromatosis type 1: a case report

    Directory of Open Access Journals (Sweden)

    Harty James A

    2011-03-01

    Full Text Available Abstract Introduction Neurofibromatosis type-1 is a common genetic disorder which often affects the skeleton. Skeletal manifestations of neurofibromatosis type-1 include scoliosis, congenital pseudarthrosis of the tibia and intraosseous cystic lesions. Dislocation of the hip associated with neurofibromatosis type-1 is a rare occurrence and is underreported in the literature. Case presentation We report a case of hip dislocation resulting from an intra-articular neurofibroma in an 18-year-old Caucasian woman following minor trauma. This was originally suggested by the abnormalities on early radiographs of her pelvis and later confirmed with computed tomography and magnetic resonance imaging. Treatment was successful with skeletal traction for six weeks with no further hip dislocations at a 12-year follow-up. Conclusion This case illustrates the radiological features of this rare complication of neurofibromatosis type-1 using the modalities of plain radiograph, magnetic resonance imaging and computed tomography reconstruction. The radiological images give a clear insight into the mechanism by which neurofibromatosis type-1 leads to hip dislocation. It also demonstrates one treatment option with excellent results on long-term follow-up.

  16. Underscreening in concentrated electrolytes.

    Science.gov (United States)

    Lee, Alpha A; Perez-Martinez, Carla S; Smith, Alexander M; Perkin, Susan

    2017-07-01

    Screening of a surface charge by an electrolyte and the resulting interaction energy between charged objects is of fundamental importance in scenarios from bio-molecular interactions to energy storage. The conventional wisdom is that the interaction energy decays exponentially with object separation and the decay length is a decreasing function of ion concentration; the interaction is thus negligible in a concentrated electrolyte. Contrary to this conventional wisdom, we have shown by surface force measurements that the decay length is an increasing function of ion concentration and Bjerrum length for concentrated electrolytes. In this paper we report surface force measurements to test directly the scaling of the screening length with Bjerrum length. Furthermore, we identify a relationship between the concentration dependence of this screening length and empirical measurements of activity coefficient and differential capacitance. The dependence of the screening length on the ion concentration and the Bjerrum length can be explained by a simple scaling conjecture based on the physical intuition that solvent molecules, rather than ions, are charge carriers in a concentrated electrolyte.

  17. Technical report: fabrication of PWR type rodlet fuel

    International Nuclear Information System (INIS)

    Yanagisawa, Kazuaki; Uno, Hisao; Sasajima, Hideo

    1990-06-01

    With respect to the simulated reactivity initiated accident (RIA) experiments with pre-irradiated LWR type fuel rods at nuclear safety research reactor (NSRR), there were principally three technical difficulties which should be overcome: (1) Fabrication of the rodlet fuel; Fuel rods from the commercial power reactors had an active column length by 3.6m. To utilize this for NSRR pulse experiment, rodlet fuel having an active column length by 0.12m (reduced to one thirtieth) is requested to fabricate without changing the inside fuel conditions. (2) Development of in-core instrumentations: During pre-irradiation stages, a long-sized fuel rod had dimensional changes by waterside corrosion, bowing, creep down and so on. The fuel also had greater amount of radioactive fission products. This condition is significant to in-core instrumentations to be attached to the fuel rods. Well characterized data to be obtained from these, however, are quite necessary and important from research point of view. Remote handling techniques to attach the rod pressure sensor, the cladding extensometer, the fuel extensometer, and the cladding surface thermocouple to pre-irradiated fuel rods are, therefore, requested to develop. (3) Installation of PIE equipments for pulsed rodlet fuels: PIE on the pulsed rodlet fuels are necessary to better understanding the fuel performance detaily. Equipments which can easily detect the data related to PCMI type fuel failure are matter of concern. Since 1986, the technical difficulties have been tried to overcome by all staffs belonging to Reactivity Accident Laboratory, NSRR Operation Division, Department of Reactor Fuel Examination and Hot Laboratory. This report describes the technical achievements obtained through four years work. (author)

  18. On a class of problems on interaction of stress concentrators of different types with an elastic semi-infinite plate

    Science.gov (United States)

    Mkhitaryan, S. M.

    2018-04-01

    A class of mixed boundary-value problems of mathematical theory of elasticity dealing with interaction between stress concentrators of different types (such as cracks, absolutely rigid thin inclusions, punches, and stringers) and an elastic semi-infinite plate is considered. The method of Mellin integral transformation is used to reduce solving these problems to solving singular integral equations (SIE). After the governing SIE are solved, the following characteristics of the problem are determined: tangential contact stresses under stringers, dislocation density on the crack edges, breaking stresses outside the cracks on their line of location, the stress intensity factor (SIF), crack openings, jumps of contact stresses on the edges of inclusions.

  19. Self-report and parent-report of physical and psychosocial well-being in Dutch adolescents with type 1 diabetes in relation to glycemic control

    Directory of Open Access Journals (Sweden)

    Houdijk Mieke C

    2007-02-01

    Full Text Available Abstract Background To determine physical and psychosocial well-being of adolescents with type 1 diabetes by self-report and parent report and to explore associations with glycemic control and other clinical and socio-demographic characteristics. Methods Demographic, medical and psychosocial data were gathered from 4 participating outpatient pediatric diabetes clinics in the Netherlands. Ninety-one patients completed the Child Health Questionnaire-CF87 (CHQ-CF87, Centre for Epidemiological Studies scale for Depression (CES-D, and the DFCS (Diabetes-specific Family Conflict Scale. Parents completed the CHQ-PF50, CES-D and the DFCS. Results Mean age was 14.9 years (± 1.1, mean HbA1c 8.8% (± 1.7; 6.2–15.0%. Compared to healthy controls, patients scored lower on CHQ subscales role functioning-physical and general health. Parents reported less favorable scores on the behavior subscale than adolescents. Fewer diabetes-specific family conflicts were associated with better psychosocial well-being and less depressive symptoms. Living in a one-parent family, being member of an ethnic minority and reporting lower well-being were all associated with higher HbA1c values. Conclusion Overall, adolescents with type 1 diabetes report optimal well-being and parent report is in accordance with these findings. Poor glycemic control is common, with single-parent families and ethnic minorities particularly at risk. High HbA1c values are related to lower social and family functioning.

  20. Electron transport properties of degenerate n-type GaN prepared by pulsed sputtering

    Science.gov (United States)

    Ueno, Kohei; Fudetani, Taiga; Arakawa, Yasuaki; Kobayashi, Atsushi; Ohta, Jitsuo; Fujioka, Hiroshi

    2017-12-01

    We report a systematic investigation of the transport properties of highly degenerate electrons in Ge-doped and Si-doped GaN epilayers prepared using the pulsed sputtering deposition (PSD) technique. Secondary-ion mass spectrometry and Hall-effect measurements revealed that the doping efficiency of PSD n-type GaN is close to unity at electron concentrations as high as 5.1 × 1020 cm-3. A record low resistivity for n-type GaN of 0.16 mΩ cm was achieved with an electron mobility of 100 cm2 V-1 s-1 at a carrier concentration of 3.9 × 1020 cm-3. We explain this unusually high electron mobility of PSD n-type GaN within the framework of conventional scattering theory by modifying a parameter related to nonparabolicity of the conduction band. The Ge-doped GaN films show a slightly lower electron mobility compared with Si-doped films with the same carrier concentrations, which is likely a consequence of the formation of a small number of compensation centers. The excellent electrical properties presented in this letter clearly demonstrate the striking advantages of the low-temperature PSD technique for growing high-quality and highly conductive n-type GaN.

  1. Electron transport properties of degenerate n-type GaN prepared by pulsed sputtering

    Directory of Open Access Journals (Sweden)

    Kohei Ueno

    2017-12-01

    Full Text Available We report a systematic investigation of the transport properties of highly degenerate electrons in Ge-doped and Si-doped GaN epilayers prepared using the pulsed sputtering deposition (PSD technique. Secondary-ion mass spectrometry and Hall-effect measurements revealed that the doping efficiency of PSD n-type GaN is close to unity at electron concentrations as high as 5.1 × 1020 cm−3. A record low resistivity for n-type GaN of 0.16 mΩ cm was achieved with an electron mobility of 100 cm2 V−1 s−1 at a carrier concentration of 3.9 × 1020 cm−3. We explain this unusually high electron mobility of PSD n-type GaN within the framework of conventional scattering theory by modifying a parameter related to nonparabolicity of the conduction band. The Ge-doped GaN films show a slightly lower electron mobility compared with Si-doped films with the same carrier concentrations, which is likely a consequence of the formation of a small number of compensation centers. The excellent electrical properties presented in this letter clearly demonstrate the striking advantages of the low-temperature PSD technique for growing high-quality and highly conductive n-type GaN.

  2. Type IIB Ileosigmoid knotting: a case report

    African Journals Online (AJOL)

    2016-06-03

    Jun 3, 2016 ... peritonitis [4,6,7]; hence early diagnosis and operative ... clinical and radiological presentation of type II ileosigmoid volvulus ... Emergency laparotomy with possible resection and primary anastomosis in type I or resection and ...

  3. Effects of background music on concentration of workers.

    Science.gov (United States)

    Huang, Rong-Hwa; Shih, Yi-Nuo

    2011-01-01

    Background music is a common element in daily living and the workplace. Determination of whether background music affects human work concentration is a relevant concern. Studies have found background music influences human behavior, and this study attempts to understand how background music and listener fondness for types of music affects worker concentration. This study analyzes how different types of background music--and how listeners' degree of preference for the background music--can affect listener concentration in attention testing through Randomized Controlled Trial (RCT). Data were collected from 89 workers. The participants ranged in age between 19 and 28 years old, with an average age of 24 years old. We conclude background music influenced listener attention. This influence has more to do with listener fondness for the music than with type of music. Compared to situations without background music, the likelihood of background music affecting test-taker attention performance is likely to increase with the degree to which the test-taker likes or dislikes the music. It is important not to select music that workers strongly like or dislike when making a selection of background music to avoid negatively affecting worker concentration.

  4. Radiation tolerance of Si{sub 1−y}C{sub y} source/drain n-type metal oxide semiconductor field effect transistors with different carbon concentrations

    Energy Technology Data Exchange (ETDEWEB)

    Nakashima, Toshiyuki, E-mail: nakashima_t@cdk.co.jp [Interdisciplinary Graduate School of Agriculture and Engineering, University of Miyazaki, 1-1 Gakuen Kibanadai-nishi, Miyazaki (Japan); Chuo Denshi Kogyo Co., Ltd., 3400 Kohoyama, Matsubase, Uki, Kumamoto (Japan); Asai, Yuki; Hori, Masato; Yoneoka, Masashi; Tsunoda, Isao; Takakura, Kenichiro [Kumamoto National College of Technology, 2659-2 Suya, Koshi, Kumamoto 861-1102 (Japan); Gonzalez, Mireia Bargallo [Institut de Microelectronica de Barcelona (Centre Nacional de Microelectronica — Consejo Superior de Investigaciones Cientificas) Campus UAB, 08193 Bellaterra (Spain); Simoen, Eddy [imec, Kapeldreef 75, B-3001 Leuven (Belgium); Claeys, Cor [imec, Kapeldreef 75, B-3001 Leuven (Belgium); Department of Electrical Engineering, KU Leuven, Kasteelpark Arenberg 10, B-3001 Leuven (Belgium); Yoshino, Kenji [Interdisciplinary Graduate School of Agriculture and Engineering, University of Miyazaki, 1-1 Gakuen Kibanadai-nishi, Miyazaki (Japan)

    2014-04-30

    The 2-MeV electron radiation damage of silicon–carbon source/drain (S/D) n-type metal oxide semiconductor field effect transistors with different carbon (C) concentrations is studied. Before irradiation, an enhancement of the electron mobility with C concentration of the S/D stressors is clearly observed. On the other hand, after electron irradiation, both the threshold voltage shift and the maximum electron mobility degradation are independent on the C concentration for all electron fluences studied. These results indicate that the strain induced electron mobility enhancement due to the C doping is retained after irradiation in the studied devices. - Highlights: • We have investigated the electron irradiation effect of the Si{sub 1−y}C{sub y} S/D n-MOSFETs. • The threshold voltage variations by irradiation are independent on the C doping. • The electron-mobility decreased for all C concentrations by electron irradiation. • The strain induced mobility enhancement effect is retained after irradiation.

  5. Generalized Severe Periodontitis and Periodontal Abscess in Type 2 Diabetes: A Case Report

    Directory of Open Access Journals (Sweden)

    Sonnenschein Sarah K.

    2016-07-01

    Full Text Available The bidirectional relationship between periodontitis and diabetes mellitus can cause distinct oral symptoms that can impact the general health conditions of affected patients. The presented case report of a female diabetes type 2 patient with severe periodontitis and a periodontal abscess shows how interdisciplinary collaboration between the attending physician and dentist can significantly improve oral conditions and metabolic control.

  6. Change in the electrical conductivity of SnO2 crystal from n-type to p-type conductivity

    International Nuclear Information System (INIS)

    Villamagua, Luis; Stashans, Arvids; Lee, Po-Ming; Liu, Yen-Shuo; Liu, Cheng-Yi; Carini, Manuela

    2015-01-01

    Highlights: • Switch from n-type to p-type conductivity in SnO 2 has been studied. • Computational DFT + U method where used. • X-ray diffraction and X-ray photoelectron spectroscopy where used. • Al- and N-codoped SnO 2 compound shows stable p-type conductivity. • Low resistivity (3.657 × 10 −1 Ω cm) has been obtained. • High carrier concentration (4.858 × 10 19 cm −3 ) has been obtained. - Abstract: The long-sought fully transparent technology will not come true if the n region of the p–n junction does not get as well developed as its p counterpart. Both experimental and theoretical efforts have to be used to study and discover phenomena occurring at the microscopic level in SnO 2 systems. In the present paper, using the DFT + U approach as a main tool and the Vienna ab initio Simulation Package (VASP) we reproduce both intrinsic n-type as well as p-type conductivity in concordance to results observed in real samples of SnO 2 material. Initially, an oxygen vacancy (1.56 mol% concentration) combined with a tin-interstitial (1.56 mol% concentration) scheme was used to achieve the n-type electrical conductivity. Later, to attain the p-type conductivity, crystal already possessing n-type conductivity, was codoped with nitrogen (1.56 mol% concentration) and aluminium (12.48 mol% concentration) impurities. Detailed explanation of structural changes endured by the geometry of the crystal as well as the changes in its electrical properties has been obtained. Our experimental data to a very good extent matches with the results found in the DFT + U modelling

  7. Effect of surfactant types and their concentration on the structural characteristics of nanoclay

    Science.gov (United States)

    Zawrah, M. F.; Khattab, R. M.; Saad, E. M.; Gado, R. A.

    2014-03-01

    A series of organo-modified nanoclays was synthesized using three different surfactants having different alkyl chain lengths and concentrations [0.5-5.0 cation exchange capacity (CEC)]. These surfactants were Ethanolamine (EA), Cetyltrimethylammoniumbromide (CTAB) and Tetraoctadecylammoniumbromide (TO). The obtained modified nanoclays were characterized by X-ray diffraction (XRD), Fourier Transform Infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM) and compared with unmodified nanoclay. The results of XRD analysis indicated that the basal d-spacing has increased with increasing alkyl chain length and surfactant concentration. From the obtained microstructures of these organo-modified nanoclays, the mechanism of surfactant adsorption was proposed. At relatively low loading of surfactant, most of surfactant entered the spacing by an ion-exchange mechanism and is adsorbed onto the interlayer cation sites. When the concentration of the surfactant exceeds the CEC of clay, the surfactant molecules then adhere to the surface adsorbed surfactant. Some surfactants entered the interlayers, whereas the others were attached to the clay surface. When the concentration of surfactant increased further beyond 2.0 CEC, the surfactants might occupy the inter-particle space within the house-of-cards aggregate structure.

  8. Error exponents for entanglement concentration

    International Nuclear Information System (INIS)

    Hayashi, Masahito; Koashi, Masato; Matsumoto, Keiji; Morikoshi, Fumiaki; Winter, Andreas

    2003-01-01

    Consider entanglement concentration schemes that convert n identical copies of a pure state into a maximally entangled state of a desired size with success probability being close to one in the asymptotic limit. We give the distillable entanglement, the number of Bell pairs distilled per copy, as a function of an error exponent, which represents the rate of decrease in failure probability as n tends to infinity. The formula fills the gap between the least upper bound of distillable entanglement in probabilistic concentration, which is the well-known entropy of entanglement, and the maximum attained in deterministic concentration. The method of types in information theory enables the detailed analysis of the distillable entanglement in terms of the error rate. In addition to the probabilistic argument, we consider another type of entanglement concentration scheme, where the initial state is deterministically transformed into a (possibly mixed) final state whose fidelity to a maximally entangled state of a desired size converges to one in the asymptotic limit. We show that the same formula as in the probabilistic argument is valid for the argument on fidelity by replacing the success probability with the fidelity. Furthermore, we also discuss entanglement yield when optimal success probability or optimal fidelity converges to zero in the asymptotic limit (strong converse), and give the explicit formulae for those cases

  9. ["Anxiety glistens on our brows". Dream reports in literary works on the horrors of ghettos and concentration camps].

    Science.gov (United States)

    Klein, J

    1991-06-01

    Dream reports occupy a special place in literature about confinement in concentration camps and ghettos (Robert Antelme, Charlotte Delbo, Anna Langfus, André Schwarz-Bart). They are central elements in the narrative that relate the anxiety of those threatened with destruction more faithfully than any realistic account could. They disrupt the chronological linearity and rationality and represent in images horror beyond memory or description.

  10. Clinical and Radiological Findings of Autosomal Dominant Osteopetrosis Type II: A Case Report

    Directory of Open Access Journals (Sweden)

    Priyanka Kant

    2013-01-01

    Full Text Available Osteopetrosis is a rare inherited genetic disease characterized by sclerosis of the skeleton caused by the absence or malfunction of osteoclasts. Three distinct forms of the disease have been recognized, autosomal dominant osteopetrosis being the most common. Autosomal dominant osteopetrosis exhibits a heterogeneous trait with milder symptoms, often at later childhood or adulthood. The aim of this case report is to present the clinical and radiographic features of a 35-year-old female patient with autosomal dominant osteopetrosis type II who exhibited features of chronic generalised periodontitis, and the radiographs revealed generalised osteosclerosis and hallmark radiographic features of ADO type II, that is, “bone-within-bone appearance” and “Erlenmeyer-flask deformity.”

  11. Validation of Reported Whole-Grain Intake from a Web-Based Dietary Record against Plasma Alkylresorcinol Concentrations in 8- to 11-Year-Olds Participating in a Randomized Controlled Trial

    DEFF Research Database (Denmark)

    Biltoft-Jensen, Anja Pia; Damsgaard, Camilla T.; W. Andersen, Elisabeth

    2016-01-01

    meal × 3 mo crossover trial. Reported WG intake and plasma AR concentrations were compared when children ate their usual bread-based lunch (UBL) and when served a hot lunch meal (HLM). Correlations and cross-classification were used to rank subjects according to intake. The intraclass correlation......BACKGROUND: Whole-grain (WG) intake is important for human health, but accurate intake estimation is challenging. Use of a biomarker for WG intake provides a possible way to validate dietary assessment methods. OBJECTIVE: Our aim was to validate WG intake from 2 diets reported by children, using...... plasma alkylresorcinol (AR) concentrations, and to investigate the 3-mo reproducibility of AR concentrations and reported WG intake. METHODS: AR concentrations were analyzed in fasting blood plasma samples, and WG intake was estimated in a 7-d web-based diary by 750 participants aged 8-11 y in a 2 school...

  12. CCE measurements and annealing studies on proton-irradiated p-type MCz silicon diodes

    CERN Document Server

    Hoedlmoser, H; Köhler, M; Nordlund, H

    2007-01-01

    Magnetic Czochralski (MCz) silicon has recently been investigated for the development of radiation tolerant detectors for future high-luminosity HEP experiments. A study of p-type MCz Silicon diodes irradiated with protons up to a fluence of has been performed by means of Charge Collection Efficiency (CCE) measurements as well as standard CV/IV characterizations. The changes of CCE, full depletion voltage and leakage current as a function of fluence are reported. A subsequent annealing study of the irradiated detectors shows an increase in effective doping concentration and a decrease in the leakage current, whereas the CCE remains basically unchanged. Two different series of detectors have been compared differing in the implantation dose of p-spray isolation as well as effective doping concentration (Neff) of the p-type bulk presumably due to a difference in thermal donor (TD) activation during processing. The series with the higher concentration of TDs shows a delayed reverse annealing of Neff after irradia...

  13. Research project implementation of a risk-based performance monitoring system for nuclear power plants: Phase II - Type-D indicators. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sewell, R.T. [EQE International. Inc., Evergreen, CO (United States); Khatib-Rahbar, M. [Energy Research, Inc., Rockville, MD (United States); Erikson, H. [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

    1999-02-01

    This study has established the basis for incorporating a meaningful set of Type-D performance indicators into an overall performance monitoring system based on a PSA framework. The relationships developed as part of this study enable various organizational, maintenance, and operational influences, that are manifested through key events that can be identified and reported at a plant, to be accounted for in terms of their impacts on safety. The relationships and the capability they pose are significant new and unique developments. The relationships require that plant-specific data on the key performance indicators be acquired and analyzed. This, in turn, necessitates that a regular and systematic supplementary data collection program be implemented. Hence, it is recommended here that such a data program be developed and undertaken, specifically within the context of an overall PSA-based safety monitoring system. Plant licensees should be responsible for the supplemental data collection effort; however, the data collection requirements should not pose an undue burden on the licensees. To the extent possible, the data collection program should be coordinated, and possibly integrated, with existing licensee data collection and event reporting efforts. This study was undertaken to help verify whether or not it would be feasible to proceed with a PSA-based performance monitoring program. Research performed for Part-1 investigation has resulted in the development of a systematic and structured approach for monitoring safety performance based on all types of plant events. The Type-D relationships were earlier identified as a key element of the proposed performance monitoring system, and if it would be discovered that the Type-D relationships could not be practically developed and implemented, then it would have lead to the recognition that the performance monitoring system might have little practical value. On the other hand, if the Type-D relationships could be efficiently

  14. Research project implementation of a risk-based performance monitoring system for nuclear power plants: Phase II - Type-D indicators. Final report

    International Nuclear Information System (INIS)

    Sewell, R.T.; Khatib-Rahbar, M.; Erikson, H.

    1999-02-01

    This study has established the basis for incorporating a meaningful set of Type-D performance indicators into an overall performance monitoring system based on a PSA framework. The relationships developed as part of this study enable various organizational, maintenance, and operational influences, that are manifested through key events that can be identified and reported at a plant, to be accounted for in terms of their impacts on safety. The relationships and the capability they pose are significant new and unique developments. The relationships require that plant-specific data on the key performance indicators be acquired and analyzed. This, in turn, necessitates that a regular and systematic supplementary data collection program be implemented. Hence, it is recommended here that such a data program be developed and undertaken, specifically within the context of an overall PSA-based safety monitoring system. Plant licensees should be responsible for the supplemental data collection effort; however, the data collection requirements should not pose an undue burden on the licensees. To the extent possible, the data collection program should be coordinated, and possibly integrated, with existing licensee data collection and event reporting efforts. This study was undertaken to help verify whether or not it would be feasible to proceed with a PSA-based performance monitoring program. Research performed for Part-1 investigation has resulted in the development of a systematic and structured approach for monitoring safety performance based on all types of plant events. The Type-D relationships were earlier identified as a key element of the proposed performance monitoring system, and if it would be discovered that the Type-D relationships could not be practically developed and implemented, then it would have lead to the recognition that the performance monitoring system might have little practical value. On the other hand, if the Type-D relationships could be efficiently

  15. Small Cell Carcinoma of the Ovary of Hypercalcemic Type: A Case Report

    Directory of Open Access Journals (Sweden)

    S. Zaied

    2012-01-01

    Full Text Available Introduction. The small cell carcinoma of hypercalcemic type of ovary is a very aggressive tumor. It is associated with two-thirds of cases with hypercalcemia most often asymptomatic. It occurs mostly for young women. The treatment combines surgery, chemotherapy, and radiotherapy. Case Presentation. We report a case of small cell carcinoma of the ovary hypercalcemic type in a young Tunisian woman aged 25 years after a severe abdominal pain syndrome and a large ovarian mass discovered in scanner; a laparotomy was performed by radical surgery. The pathological examination of the specimen confirmed the diagnosis. The radiological assessment performed after surgery showed a continuing evolution. Palliative chemotherapy was established, and the patient had died two months after diagnosis. Conclusion. The hypercalcemic small cell carcinoma of the ovary is a rare disease of poor prognosis.

  16. Peripheral nerve blocks in patients with Ehlers-Danlos syndrome, hypermobility type: a report of 2 cases.

    Science.gov (United States)

    Patzkowski, Michael S

    2016-03-01

    Ehlers-Danlos syndrome is an inherited disorder of collagen production that results in multiorgan dysfunction. Patients with hypermobility type display skin hyperextensibility and joint laxity, which can result in chronic joint instability, dislocation, peripheral neuropathy, and severe musculoskeletal pain. A bleeding diathesis can be found in all subtypes of varying severity despite a normal coagulation profile. There have also been reports of resistance to local anesthetics in these patients. Several sources advise against the use of regional anesthesia in these patients citing the 2 previous features. There have been reports of successful neuraxial anesthesia, but few concerning peripheral nerve blocks, none of which describe nerves of the lower extremity. This report describes 2 cases of successful peripheral regional anesthesia in the lower extremity. In case 1, a 16-year-old adolescent girl with hypermobility type presented for osteochondral grafting of tibiotalar joint lesions. She underwent a popliteal sciatic (with continuous catheter) and femoral nerve block under ultrasound guidance. She proceeded to surgery and tolerated the procedure under regional block and intravenous sedation. She did not require any analgesics for the following 15 hours. In case 2, an 18-year-old woman with hypermobility type presented for medial patellofemoral ligament reconstruction for chronic patella instability. She underwent a saphenous nerve block above the knee with analgesia in the distribution of the saphenous nerve lasting for approximately 18 hours. There were no complications in either case. Prohibitions against peripheral nerve blocks in patients with Ehlers-Danlos syndrome, hypermobility type, appear unwarranted. Published by Elsevier Inc.

  17. Experimental characterization of a concentrating photovoltaic system varying the light concentration

    International Nuclear Information System (INIS)

    Renno, C.; Petito, F.; Landi, G.; Neitzert, H.C.

    2017-01-01

    Highlights: • Experimental characterization of a concentrating photovoltaic system. • Analysis of the point-focus concentrating system performances. • Photovoltaic system parameters as function of the concentration factor. - Abstract: The concentrating photovoltaic system represents one of the most promising solar technologies because it allows a more efficient energy conversion. When a CPV system is designed, the main parameter which has to be considered is the concentration factor that affects both the system energy performances and its configuration. An experimental characterization of a CPV system previously realized at the University of Salerno, is presented in this paper considering several aspects related to the optical configuration, the concentration factor and the solar cell used. In particular, the parameters of an Indium Gallium Phosphide/Gallium Arsenide/Germanium triple-junction solar cell are investigated as function of the concentration factor determined by means of an experimental procedure that uses different optical configurations. The maximum concentration factor reached by the CPV system is 310 suns. The cell parameters dependence on the concentration is reported together with an electroluminescence analysis of the Indium Gallium Phosphide/Gallium Arsenide/Germanium cell. A monitoring of the electrical power provided by the system during its working is also presented corresponding to different direct irradiance values. A mean power of 2.95 W with an average efficiency of 32.8% is obtained referring to a mean irradiance of 930 W/m"2; lower values are obtained when the irradiance is highly fluctuating. The concentrating photovoltaic system electric energy output is estimated considering different concentration levels; the maximal obtained value is 23.5 W h on a sunny day at 310×. Finally, the temperature of the triple-junction solar cell is evaluated for different months in order to evaluate the potential annual thermal energy production

  18. Generation of high-titer viral preparations by concentration using successive rounds of ultracentrifugation

    Directory of Open Access Journals (Sweden)

    Ichim Christine V

    2011-08-01

    Full Text Available Abstract Background Viral vectors provide a method of stably introducing exogenous DNA into cells that are not easily transfectable allowing for the ectopic expression or silencing of genes for therapeutic or experimental purposes. However, some cell types, in particular bone marrow cells, dendritic cells and neurons are difficult to transduce with viral vectors. Successful transduction of such cells requires preparation of highly concentrated viral stocks, which permit a high virus concentration and multiplicity of infection (MOI during transduction. Pseudotyping with the vesicular stomatitis virus G (VSV-G envelope protein is common practice for both lentiviral and retroviral vectors. The VSV-G glycoprotein adds physical stability to retroviral particles, allowing concentration of virus by high-speed ultracentrifugation. Here we describe a method report for concentration of virus from large volumes of culture supernatant by means of successive rounds of ultracentrifugation into the same ultracentrifuge tube. Method Stable retrovirus producer cell lines were generated and large volumes of virus-containing supernatant were produced. We then tested the transduction ability of virus following varying rounds of concentration by ultra-centrifugation. In a second series of experiments lentivirus-containing supernatant was produced by transient transfection of 297T/17 cells and again we tested the transduction ability of virus following multiple rounds of ultra-centrifugation. Results We report being able to centrifuge VSV-G coated retrovirus for as many as four rounds of ultracentrifugation while observing an additive increase in viral titer. Even after four rounds of ultracentrifugation we did not reach a plateau in viral titer relative to viral supernatant concentrated to indicate that we had reached the maximum tolerated centrifugation time, implying that it may be possible to centrifuge VSV-G coated retrovirus even further should it be necessary

  19. Undoped p-type GaN1-xSbx alloys: Effects of annealing

    Science.gov (United States)

    Segercrantz, N.; Baumgartner, Y.; Ting, M.; Yu, K. M.; Mao, S. S.; Sarney, W. L.; Svensson, S. P.; Walukiewicz, W.

    2016-12-01

    We report p-type behavior for undoped GaN1-xSbx alloys with x ≥ 0.06 grown by molecular beam epitaxy at low temperatures (≤400 °C). Rapid thermal annealing of the GaN1-xSbx films at temperatures >400 °C is shown to generate hole concentrations greater than 1019 cm-3, an order of magnitude higher than typical p-type GaN achieved by Mg doping. The p-type conductivity is attributed to a large upward shift of the valence band edge resulting from the band anticrossing interaction between localized Sb levels and extended states of the host matrix.

  20. Slow growing desmoid-type fibromatosis of the breast: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Ah Reum; Kim, Ji Young; Kim, Hyun Jung; KIm, Jae Hyung; Jeong, Myeong Ja; Kim, Soung Hee; Kim, Soo Hyun; Kang, Mi Jin; Lee, Ji Hae; Bae, Kyung Eun [Sanggye Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of)

    2017-04-15

    Fibromatosis or desmoid tumor of the breast is a rare benign entity that has no metastatic potential but has significant risk of local recurrence. Its association with previous surgical or accidental trauma and Gardner's syndrome has been reported. Awareness of this lesion is important as the diagnosis is often confused with breast carcinoma. We report a case of a 44-year-old woman who presented with a palpable mass in her left breast, close to the axilla since a few months ago. She had undergone excisional biopsy for her left breast mass 15 months ago, and the diagnosis was confirmed as intraductal papilloma with atypical ductal hyperplasia. Subsequent ultrasound and core needle biopsy revealed stromal fibrosis. After 9 months, the mass showed an increase in its size and the anteroposterior to width ratio on ultrasonography compared to the previous examination, and final excisional biopsy confirmed the diagnosis of desmoid-type fibromatosis.

  1. Clinical value of the joint measurement of serum concentrations of type IV collagen and laminin in patients with diabetic nephropathy

    International Nuclear Information System (INIS)

    Wang Lu; Wang Ping; Li Yongpei

    2004-01-01

    Objective: To study clinical value of the joint measurement of serum concentrations of type IV collagen (IV C) and laminin (LN) in patients with diabetic nephropathy (DN) by radioimmunoassay (RIA). Methods: Serum concentrations of IV C, LN were measured by RIA in 35 diabetic patients with normalbuminuria (group A), 28 cases of microalbuminuria (group B), 15 cases of macroalbuminuria (group C) and 30 normal subjects as control . Results: The serum concentrations of IV C, LN in total 78 diabetic patients [(97.6 ± 19.2), (132.4 ± 31.5) μg/L] were higher than that of the controls [(77.4 ± 8.2), (101.5 ± 17.6) μg/L, P<0.05], especially in group B and C, it was remarkably higher compared with the controls (P<0.05, P<0.01). There was significant positive correlation of serum IV C, LN to diabetic duration and the levels of blood urea nitrogen (BUN), creatinine (Cr), urinary albumin excretion rate (UAER). Conclusions: The results suggest that the joint measurement of serum levels of IV C, LN and UAER in DN patients might better evaluate the development process of DN, and be of help for early diagnosis and treatment of DN. Serum levels of IV C, LN and UAER in DN patients may become the reliable clinical markers for assessing the severity and predicting the prognosis of DN

  2. Adenocarcinoma arising in a heterotopic pancreas (Heinrich type III: a case report

    Directory of Open Access Journals (Sweden)

    Egashira Yutaro

    2010-02-01

    Full Text Available Abstract Introduction Heterotopic pancreatic cancer in the duodenum is a very rare disease. Only twelve cases have been reported worldwide to date. We report a rare case of malignant transformation of heterotopic pancreas (Heinrich type III in the duodenum with long-term survival of the patient, and review the 12 cases in the literature. Case presentation A 75-year-old Japanese man was admitted to our hospital complaining of nausea and vomiting. Endoscopy and upper gastrointestinal contrast study showed marked duodenal stenosis. A pylorus-preserving pancreaticoduodenectomy was performed. Histopathological examination of the surgically resected specimen showed malignant transformation of heterotopic pancreas (Heinrich type III in the duodenum. The postoperative course was uneventful, and the patient was discharged from the hospital on postoperative day 30. He is well and shows no signs of recurrence at the time of writing, six years after the surgery. Conclusion Adenocarcinoma arising within the heterotopic pancreas appears to be rare. It is difficult to obtain a correct diagnosis preoperatively. The management of heterotopic pancreas depends on the presence or absence of symptoms. If the patient is asymptomatic or benign, conservative treatment with regular follow-up is recommended. When the patient is symptomatic or there is a suspicion of malignancy, surgical management with intra-operative frozen section diagnosis is indicated.

  3. [Diuretics and their potential effect on breath-alcohol concentration--a case report].

    Science.gov (United States)

    Schmitt, Georg; Skopp, Gisela

    2015-01-01

    Many objections were raised to breath-alcohol analysis upon its introduction in the field of traffic law enforcement in Germany, but in the meantime this issue has become less relevant in forensic routine work. In the present case, the defending lawyer claimed that the ethanol concentration in the blood and hence in the breath of his client, which was 0.35 mg/l according to the Dräger Alcotest 7110® Evidential and thus above the legal limit of 0.25 mg/l, had been changed by diuretics taken 4 hours before the breath alcohol test, viz. 10 mg of torasemide, a loop diuretic, and 50 mg of spironolactone, a competitive aldosterone antagonist. According to the literature, the maximum urinary output in healthy subjects within the first 4 hours after 10 mg torasemide was 1450 ml. In patients suffering from heart failure, the urinary volume was reduced by a factor of 2.5-3; after chronic intake of torasemide, water loss did not differ from placebo. Spironolactone, which acts on the distal tubule, has little effect on urinary output. In a publication, the loss of water in excess within 24 hours was 90 ml. Co-administration of 100 mg spironolactone and 20 mg furosemide, which roughly compares to 10 mg torasemide, resulted in a mean urinary volume of 1566 ml within the first 4 hours. In terms of the reported case and provided that no compensatory fluid had been taken, a purely theoretical maximum shift of 0.007 mg/ may occur in the breath-alcohol concentration due to the smaller distribution volume even considering maximum urinary excretion values. On the other hand, already mild levels of dehydration may be associated with negative symptoms affecting driving ability.

  4. Sediment acoustic index method for computing continuous suspended-sediment concentrations

    Science.gov (United States)

    Landers, Mark N.; Straub, Timothy D.; Wood, Molly S.; Domanski, Marian M.

    2016-07-11

    Suspended-sediment characteristics can be computed using acoustic indices derived from acoustic Doppler velocity meter (ADVM) backscatter data. The sediment acoustic index method applied in these types of studies can be used to more accurately and cost-effectively provide time-series estimates of suspended-sediment concentration and load, which is essential for informed solutions to many sediment-related environmental, engineering, and agricultural concerns. Advantages of this approach over other sediment surrogate methods include: (1) better representation of cross-sectional conditions from large measurement volumes, compared to other surrogate instruments that measure data at a single point; (2) high temporal resolution of collected data; (3) data integrity when biofouling is present; and (4) less rating curve hysteresis compared to streamflow as a surrogate. An additional advantage of this technique is the potential expansion of monitoring suspended-sediment concentrations at sites with existing ADVMs used in streamflow velocity monitoring. This report provides much-needed standard techniques for sediment acoustic index methods to help ensure accurate and comparable documented results.

  5. Studies on indoor radon concentrations in Karimanagar district of Telangana State, India

    International Nuclear Information System (INIS)

    Srinivas Reddy, G.; Vinay Kumar Reddy, K.; Sreenivasa Reddy, B.; Ch Gopal Reddy, P.; Yadagiri Reddy, P.; Rama Reddy, K.

    2015-01-01

    Karimnagar district of Telangana state in India falls geologically under the Karimnagar Granulite Terrain (KGT) and, is well known for several types of granites. Studies revealed that the radiation levels are elevated with these granitic rocks. The indoor radon concentrations are estimated in about 80 dwellings, selected randomly in Karimnagar district, using LR-115 Type-II Solid State Nuclear Track Detectors based Twin Chamber Cup dosimeters for a period of one year on quarterly basis. The dose rates due to the radon concentrations are calculated. The seasonal variations of the indoor radon concentrations have been studied. Further, the dependency of indoor radon concentrations on different types of dwellings is also discussed in the present paper. (author)

  6. Source contributions to atmospheric fine carbon particle concentrations

    Science.gov (United States)

    Andrew Gray, H.; Cass, Glen R.

    A Lagrangian particle-in-cell air quality model has been developed that facilitates the study of source contributions to atmospheric fine elemental carbon and fine primary total carbon particle concentrations. Model performance was tested using spatially and temporally resolved emissions and air quality data gathered for this purpose in the Los Angeles area for the year 1982. It was shown that black elemental carbon (EC) particle concentrations in that city were dominated by emissions from diesel engines including both on-highway and off-highway applications. Fine primary total carbon particle concentrations (TC=EC+organic carbon) resulted from the accumulation of small increments from a great variety of emission source types including both gasoline and diesel powered highway vehicles, stationary source fuel oil and gas combustion, industrial processes, paved road dust, fireplaces, cigarettes and food cooking (e.g. charbroilers). Strategies for black elemental carbon particle concentration control will of necessity need to focus on diesel engines, while controls directed at total carbon particle concentrations will have to be diversified over a great many source types.

  7. Savannah River Site environmental report for 1989

    Energy Technology Data Exchange (ETDEWEB)

    Cummins, C.L.; Martin, D.K.; Todd, J.L.

    1989-01-01

    this volume of Savannah River Site Environmental Report for 1989 (WSRC-IM-90-60) contains the figures and tables referenced in Volume I. The figures contain graphic illustrations of sample locations and/or data. The tables present summaries of the following types of data federal and state standards and guides applicable to SRS operations; concentrations of radioactivity in environmental media; the quantity of radioactivity released to the environment from SRS operations; offsite radiation committed dose from SRS operations; measurements of physical properties, chemicals, and metals concentrations in environmental media; and interlaboratory comparison of analytical results. The figures and tables in this report contain information about the routine environmental monitoring program at SRS unless otherwise indicated. No attempt has been made to include all data from environmental research programs. Variations in the report's content from year to year reflect changes in the routine environmental monitoring program or the inability to obtain certain samples from a specific location. 42 figs., 188 tabs.

  8. Savannah River Site environmental report for 1989

    International Nuclear Information System (INIS)

    Cummins, C.L.; Martin, D.K.; Todd, J.L.

    1989-01-01

    this volume of Savannah River Site Environmental Report for 1989 (WSRC-IM-90-60) contains the figures and tables referenced in Volume I. The figures contain graphic illustrations of sample locations and/or data. The tables present summaries of the following types of data federal and state standards and guides applicable to SRS operations; concentrations of radioactivity in environmental media; the quantity of radioactivity released to the environment from SRS operations; offsite radiation committed dose from SRS operations; measurements of physical properties, chemicals, and metals concentrations in environmental media; and interlaboratory comparison of analytical results. The figures and tables in this report contain information about the routine environmental monitoring program at SRS unless otherwise indicated. No attempt has been made to include all data from environmental research programs. Variations in the report's content from year to year reflect changes in the routine environmental monitoring program or the inability to obtain certain samples from a specific location. 42 figs., 188 tabs

  9. Savannah River Site environmental report for 1988

    Energy Technology Data Exchange (ETDEWEB)

    Cummins, C.L.; Hetrick, C.S.; Stevenson, D.A. (eds.); Davis, H.A.; Martin, D.K.; Todd, J.L.

    1989-01-01

    This volume of Savannah River Site Environmental report for 1988 (WSRC-RP-89-59-1) contains the figures and tables referenced in Volume 1. The figures contain graphic illustrations of sample locations and/or data. The tables contain summaries of the following types of data: Federal and State standards and guides applicable to SRS operations; concentrations of radioactivity in environmental media; the quantity of radioactivity released to the environment from SRS operations; offsite radiation dose commitments from SRS operations; measurements of physical properties, chemicals, and metals concentrations in environmental media; and interlaboratory comparison of analytical results.

  10. Effects of soil type and genotype on lead concentration in rootstalk vegetables and the selection of cultivars for food safety.

    Science.gov (United States)

    Ding, Changfeng; Zhang, Taolin; Wang, Xingxiang; Zhou, Fen; Yang, Yiru; Yin, Yunlong

    2013-06-15

    Lead (Pb) contamination of soil poses severe health risks to humans through vegetable consumption. The variations of Pb concentration in different parts of rootstalk vegetables (radish, carrot and potato) were investigated by using twelve cultivars grown in acidic Ferralsols and neutral Cambisols under two Pb treatments (125 mg kg(-1) and 250 mg kg(-1) for Ferralsols; 150 mg kg(-1) and 300 mg kg(-1) for Cambisols) in a pot experiment. The Pb concentration in edible parts was higher in Ferralsols under two Pb treatments, with range from 0.28 to 4.14, 0.42-10.66 mg kg(-1) (fresh weight) respectively, and all of them exceeded the food safety standard (0.1 mg kg(-1)) recommended by the Codex Alimentarius Commission of FAO and WHO. The Pb concentration in edible parts was significantly affected by genotype, soil type and the interaction between these two factors. The variation of Pb concentration in different cultivars was partially governed by Pb absorption and the transfer of Pb from aerial to edible part. The results revealed that caution should be paid to the cultivation of rootstalk vegetables in Pb-contaminated Ferralsols without any agronomic management to reduce Pb availability and plant uptake. For Cambisols with slight to moderate Pb contamination, growing potato cultivar Shandong No.1 and Chongqing No.1 was effective in reducing the risk of Pb entering human food chain. The results suggest the possibility of developing cultivar- and soil-specific planting and monitoring guidelines for the cultivation of rootstalk vegetables on slight to moderate Pb-contaminated soils. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Blood glucose monitoring and glycemic control in adolescents with type 1 diabetes: meter downloads versus self-report.

    Science.gov (United States)

    Guilfoyle, Shanna M; Crimmins, Nancy A; Hood, Korey K

    2011-09-01

    Reported frequencies of blood glucose monitoring (BGM) by both adolescents and their caregivers serve as adherence proxies when meter downloads are not available. Yet, correlates of reported BGM frequencies and their predictive utility are understudied. To identify sociodemographic, psychological, and disease-specific correlates of reported BGM frequencies in adolescents with type 1 diabetes and to explore the predictive utility of BGM indices on glycemic control. Study participants included caregivers and adolescents with type 1 diabetes (N=143, 13-18 yr) receiving diabetes treatment at a tertiary care setting. At the initial visit, adolescents and caregivers reported on daily BGM frequencies. A sub-sample provided meter downloads. Adolescents also completed a depression inventory. Three months later, adolescents provided blood sampling for A1c assessment. Multivariate general linear modeling identified that older adolescent age and more depressive symptoms were associated with reports of less frequent BGM. Two stepwise multivariate regression models examined the predictive utility of BGM indices (i.e., adolescent-reported BGM, caregiver-reported BGM, meter download) on glycemic control. Caregiver-reported BGM frequency predicted glycemic control in the absence of meter download data (pmeter download data were the most robust predictor of glycemic control (pMeter downloads have the most robust association with glycemic control when contextual variables are considered. Caregiver-reported BGM frequencies can serve as reliable substitutes in the absence of meter download, but they may not be as reliable in adolescents with depressive symptoms. © 2011 John Wiley & Sons A/S.

  12. Fission-nuclide concentrations of ambient aerosol separated by size

    International Nuclear Information System (INIS)

    Csepregi, T.; Kovacs, L.; Maschek, I.; Szterjopulos, K.

    1984-01-01

    Examinations were carried on the radionuclides in aerosol deposited on filters of an air-conditioning plant with high air flow rate. For nuclide concentration of ambient air qualitative and quantitative analyses were made by gamma spectrometry. Methods have been developed for sample preparation, size fractionation by sedimentation technique and measurement of air flow. The collected aerosol particles was separated into five size fractions from 1 to 5 μm and the aerosol fractions were analysed. The mass/size distribution of the particles processed by sedimentation has been compared with that of the ambient aerosol separated by a slot impactor Hungarian type. Because the aggregation caused by the resuspensationtechnique would be assumed, electronmicrophotos were made on processed and unprocessed aerosols. On the basis of them the particle aggregation may be negligible. Otherwise, the derivation of concentration needs to know the exact air volume. For this aim the technical parameters of the aerodynamic system have also been measured in two different ways. The paper reports on the size dependence of fission products originating from the present global late fallout for a two years monitoring period. The results are compared with the daily beta activity concentration of aerosol samples taken by an other sampling unit. (Author)

  13. Instability predictions for circumferentially cracked Type-304 stainless-steel pipes under dynamic loading. Final report. [BWR

    Energy Technology Data Exchange (ETDEWEB)

    Zahoor, A.; Wilkowski, G.; Abou-Sayed, I.; Marschall, C.; Broek, D.; Sampath, S.; Rhee, H.; Ahmad, J.

    1982-04-01

    This report provides methods to predict margins of safety for circumferentially cracked Type 304 stainless steel pipes subjected to applied bending loads. An integrated combination of experimentation and analysis research was pursued. Two types of experiments were performed: (1) laboratory-scale tests on center-cracked panels and bend specimens to establish the basic mechanical and fracture properties of Type 304 stainless steel, and (2) full-scale pipe fracture tests under quasi-static and dynamic loadings to assess the analysis procedures. Analyses were based upon the simple plastic collapse criterion, a J-estimation procedure, and elastic-plastic large-deformation finite element models.

  14. Determination of the concentration of {alpha} emitting radioactive aerosols; Mesure de la concentration des aerosols radioactifs emetteurs {alpha}

    Energy Technology Data Exchange (ETDEWEB)

    Labeyrie, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1953-06-15

    In the first part of this work the techniques used for the quantitative measurement of the concentrations of aerosols carrying short lived (radon or thoron daughters) or long lived (uranium) {alpha} radioactive emitters are described. In the second part the author investigates the problem of the determination of radon concentration in air by means of activity determinations on airborne dusts. Special reference is made to the measurement of the radon active deposit on two types of dusts (iron oxide (yellow) and uranium oxide) in small chambers (6 liters). In the third part are given data resulting from determinations of radon and thoron concentrations in atmospheric air in the south of Paris area using this method. (author) [French] Dans la premiere partie de ce travail on expose les techniques utilisees pour la mesure quantitative des concentrations d'aerosols contenant des emetteurs radioactifs {alpha}, tant pour ceux a vie courte (derives du radon ou du thoron) que pour ceux a vie longue (uranium). Dans la seconde partie on traite le probleme de la determination de la concentration de l'air en radon par la mesure de l'activite des poussieres ayant sejourne dans cet air. En particulier, on indique pour de petits volumes (6 litres) la proportion de depot actif du radon qui est fixee sur deux types de poussieres (limonite et oxyde d'uranium) en fonction de la concentration de celles-ci. Dans la troisieme partie on donne quelques exemples de mesure par cette methode de la concentration en radon et en thoron de l'atmosphere de la region parisienne. (auteur)

  15. Spontaneous remission of chiasmatic/hypothalamic masses in neurofibromatosis type 1: report of two cases

    International Nuclear Information System (INIS)

    Gottschalk, S.; Tavakolian, R.; Lehmann, R.; Buske, A.; Tinschert, S.

    1999-01-01

    We report two children with neurofibromatosis type 1 showing enhancing masses on MRI suggesting neoplasms in the chiasm and hypothalamic region. In both patients no visual or endocrinal dysfunction was present. On serial MRI spontaneous partial remission was found, implying that a cautious approach to therapeutic management of similar cases should be taken. (orig.) (orig.)

  16. Aquatic Therapy for a Child with Type III Spinal Muscular Atrophy: A Case Report

    Science.gov (United States)

    Salem, Yasser; Gropack, Stacy Jaffee

    2010-01-01

    Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by degeneration of alpha motor neurons. This case report describes an aquatic therapy program and the outcomes for a 3-year-old girl with type III SMA. Motor skills were examined using the 88-item Gross Motor Function Measure (GMFM), the Peabody Developmental Motor Scales…

  17. Fulminant type 1 diabetes mellitus: a case report

    Science.gov (United States)

    Yunir, E.; Nenfiati

    2018-03-01

    Type 1 diabetes mellitus is a metabolic disease caused by insulin deficiency that results from destruction of β-cells in the pancreas. Based on American Diabetes Association, there are two types of type 1 diabetes mellitus: type 1A (autoimmune) and 1B (idiopathic). In this case, we are presenting a new archetype of type 1 diabetes named fulminant type 1 diabetes mellitus. This disease results from quick destruction of β-cells byanautoimmune mechanism. The manifestation of this disease consists of unspecific flu-like symptoms, abdominal symptoms, to specific hyperglycemia symptoms such as fatigue, malaise, change in mental status that are attributable to high blood glucose and ketosis. Laboratory examination reveals high blood glucose, normal glycosylated hemoglobin, ketosis or ketoacidosis, potassium depletion and elevation of liver function tests. Treatment consists of intravenous infusion followed by insulin injection for blood glucose control, followed by treatment of metabolic derangements such as acid-base and electrolyte disorder.

  18. First genome report on novel sequence types of Neisseria meningitidis: ST12777 and ST12778.

    Science.gov (United States)

    Veeraraghavan, Balaji; Lal, Binesh; Devanga Ragupathi, Naveen Kumar; Neeravi, Iyyan Raj; Jeyaraman, Ranjith; Varghese, Rosemol; Paul, Miracle Magdalene; Baskaran, Ashtawarthani; Ranjan, Ranjini

    2018-03-01

    Neisseria meningitidis is an important causative agent of meningitis and/or sepsis with high morbidity and mortality. Baseline genome data on N. meningitidis, especially from developing countries such as India, are lacking. This study aimed to investigate the whole genome sequences of N. meningitidis isolates from a tertiary care centre in India. Whole-genome sequencing was performed using an Ion Torrent™ Personal Genome Machine™ (PGM) with 400-bp chemistry. Data were assembled de novo using SPAdes Genome Assembler v.5.0.0.0. Sequence annotation was performed through PATRIC, RAST and the NCBI PGAAP server. Downstream analysis of the isolates was performed using the Center for Genomic Epidemiology databases for antimicrobial resistance genes and sequence types. Virulence factors and CRISPR were analysed using the PubMLST database and CRISPRFinder, respectively. This study reports the whole genome shotgun sequences of eight N. meningitidis isolates from bloodstream infections. The genome data revealed two novel sequence types (ST12777 and ST12778), along with ST11, ST437 and ST6928. The virulence profile of the isolates matched their sequence types. All isolates were negative for plasmid-mediated resistance genes. To the best of our knowledge, this is the first report of ST11 and ST437 N. meningitidis isolates in India along with two novel sequence types (ST12777 and ST12778). These results indicate that the sequence types circulating in India are diverse and require continuous monitoring. Further studies strengthening the genome data on N. meningitidis are required to understand the prevalence, spread, exact resistance and virulence mechanisms along with serotypes. Copyright © 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

  19. Handheld Multi-Gas Meters Assessment Report

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Gustavious [Brigham Young Univ., Provo, UT (United States); Wald-Hopkins, Mark David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Obrey, Stephen J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Akhadov, Valida Dushdurova [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-27

    Handheld multi-gas meters (MGMs) are equipped with sensors to monitor oxygen (O2) levels and additional sensors to detect the presence of combustible or toxic gases in the environment. This report is limited to operational response-type MGMs that include at least four different sensors. These sensors can vary by type and by the monitored chemical. In real time, the sensors report the concentration of monitored gases in the atmosphere near the MGM. In April 2016 the System Assessment and Validation for Emergency Responders (SAVER) Program conducted an operationally-oriented assessment of MGMs. Five MGMs were assessed by emergency responders. The criteria and scenarios used in this assessment were derived from the results of a focus group of emergency responders with experience in using MGMs. The assessment addressed 16 evaluation criteria in four SAVER categories: Usability, Capability, Maintainability, and Deployability.

  20. Report for the coal type committee meetings in fiscal 1993; 1993 nendo tanshu iinkai hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    This paper reports a joint meeting of the coal liquefaction committee and the coal type committee in fiscal 1993. The report is focussed on the coal type selection (the final report) for the coal used in the 150-t/d coal liquefaction pilot plant (PP) among other agenda. Initially the Australian Wandoan coal was scheduled to be selected as the reference coal for the PP operation, but the mine has not gone into operation, hence the schedule was given up. Screening was carried out to select a coal which is commercially produced and exported, and contains ash at 10% by weight or less, sulfur at 1.5% by weight or less, and chlorine at 300 ppm or less. An autoclave and a 0.01-t/d flowing type device were used to evaluate liquefaction performance, whereas the Tanito Harum coal produced in Indonesia, very similar to the Wandoan coal, was selected as a promising candidate. A PSU was used to demonstrate overall operation performance. The coal is an appropriate reference coal as seen from the aspects of liquefied oil yield, nature, operability, and site surveys in Indonesia. Among the actual record of four kinds of PSU coals in the past, the present coal has the oil yield ranked high, has the least liquefaction residues, and is advantageous economically. The oil yield per ton of coal has cleared the PP target of four barrels. The coal has less ash, is easy in solid/liquid separation in the depressurized distillation, and has no problems in operability, excepting the matter of coal supply. (NEDO)

  1. Controlled p-type to n-type conductivity transformation in NiO thin films by ultraviolet-laser irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Pranav; Dutta, Titas; Mal, Siddhartha; Narayan, Jagdish [Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27606 (United States)

    2012-01-01

    We report the systematic changes in structural, electrical, and optical properties of NiO thin films on c-sapphire introduced by nanosecond ultraviolet excimer laser pulses. Epitaxial nature of as deposited NiO was determined by x-ray diffraction phi scans and transmission electron microscopy (TEM) and it was established that NiO film growth takes place with twin domains on sapphire where two types of domains have 60 deg. in-plane rotation with respect to each other about the [111] growth direction. We determined that at pulsed laser energy density of 0.275 J/cm{sup 2}, NiO films exhibited conversion from p-type semiconducting to n-type conductive behavior with three orders of magnitude decrease in resistivity, while maintaining its cubic crystal structure and good epitaxial relationship. Our TEM and electron-energy-loss spectroscopy studies conclusively ruled out the presence of any Ni clustering or precipitation due to the laser treatment. The laser-induced n-type carrier transport and conductivity enhancement were shown to be reversible through subsequent thermal annealing in oxygen. This change in conductivity behavior was correlated with the nonequilibrium concentration of laser induced Ni{sup 0}-like defect states.

  2. Concentration of actinides in the food chain

    International Nuclear Information System (INIS)

    Bulman, R.A.

    1976-06-01

    Considerable concern is now being expressed over the discharge of actinides into the environment. This report presents a brief review of the chemistry of the actinides and examines the evidence for interaction of the actinides with some naturally-occurring chelating agents and other factors which might stimulate actinide concentration in the food chain of man. This report also reviews the evidence for concentration of actinides in plants and for uptake through the gastrointestinal tract. (author)

  3. Colloid-Associated Radionuclide Concentration Limits: ANL

    International Nuclear Information System (INIS)

    Mertz, C.

    2000-01-01

    The purpose and scope of this report is to describe the analysis of available colloidal data from waste form corrosion tests at Argonne National Laboratory (ANL) to extract characteristics of these colloids that can be used in modeling their contribution to the source term for sparingly soluble radioelements (e.g., Pu). Specifically, the focus is on developing a useful description of the following waste form colloid characteristics: (1) composition, (2) size distribution, and (3) quantification of the rate of waste form colloid generation. The composition and size distribution information are intended to support analysis of the potential transport of the sparingly soluble radionuclides associated with the waste form colloids. The rate of colloid generation is intended to support analysis of the waste form colloid-associated radionuclide concentrations. In addressing the above characteristics, available data are interpreted to address mechanisms controlling colloid formation and stability. This report was developed in accordance with the ''Technical Work Plan for Waste Form Degradation Process Model Report for SR'' (CRWMS M and O 2000). Because the end objective is to support the source term modeling we have organized the conclusions into two categories: (1) data analysis conclusions and (2) recommendations for colloid source term modeling. The second category is included to facilitate use of the conclusions from the data analysis in the abstraction of a colloid source term model. The data analyses and conclusions that are presented in this report are based on small-scale laboratory tests conducted on a limited number of waste glass compositions and spent fuel types

  4. Acute lymphocytic crisis following herpes simplex type 1 virus hepatitis in a nonimmunocompromised man: a case report

    Directory of Open Access Journals (Sweden)

    Plastiras Sotiris

    2009-08-01

    Full Text Available Abstract Introduction An increase in circulating lymphocytes can be seen following infections such as infectious mononucleosis and pertussis, or in lymphoproliferative disorders such as acute and chronic lymphocytic leukemia. Acute lymphocytic crisis following herpes simplex virus hepatitis has not been described in the literature. Case presentation A 52-year-old man was admitted to our hospital reporting low-grade fever for the previous seven days, and fatigue. During the fifth day of hospitalization, the patient developed a lymphocytic crisis and, after further tests the patient was diagnosed as having herpes simplex virus hepatitis. Conclusion This case report shows that herpes simplex virus type 1 is a possible cause of an acute lymphocytic crisis similar to other well known infectious agents such as Epstein–Barr virus, cytomegalovirus, human immunodeficiency virus, human herpes virus type 6, adenovirus, toxoplasma and human T-cell lymphotropic virus. Furthermore, this case report expands the clinical spectrum of herpes simplex virus hepatitis, since it is reported in a nonimmunocompromised patient presenting with atypical acute lymphocytic syndrome.

  5. Effects of naringin on apoptosis and oxidative stress in type 2 diabetic rats

    Science.gov (United States)

    Adelani, Isaacson; Bankole, Esther; Rotimi, Oluwakemi; Rotimi, Solomon

    2018-04-01

    Oxidative stress and apoptosis have been reported to play major roles in the pathogenesis of Type 2 Diabetes Mellitus (T2DM) through insulin resistance and β-cell dysfunction. Naringin is a citrus derived flavonoid that has been reported for its antioxidant properties. Even though effects of naringin in T2DM related oxidative stress has been reported, varying dose concentration in oxidative stress and mechanism of action involving T2DM related apoptosis is far-fetched. This research studied the effects of naringin at varying dose concentration on apoptosis, biomarkers of organ function and oxidative stress in high fat diet/low-streptozotocin-induced T2DM in albino Wistar rats. Diabetic rats were treated with naringin at 50mg/kg, 100mg/kg and 200mg/kg body weight for 21 days. Some biomarkers of organ function and oxidative stress in the animals were assayed using spectrophotometric techniques. The levels of expression of caspases and apoptotic regulators were quantified using semi-quantitative reverse transcriptase polymerase chain reaction (RT PCR). Enzyme - linked immunosorbent assay was used to determine inducible nitric oxide synthase (iNOS) level. Naringin treatment shows a dose dependent significant (plipid peroxidation, glutathione- s-transferase, glutathione peroxidase and glutathione reductase activities in the liver. Naringin treatment also showed a significant (p<0.05) increase in the expression of caspase 3 and reduction in BCL-2 as against the diabetic control. In addition, there was dose dependent decrease in plasma CO2 concentration and increase in the plasma iNOS concentration as compared to the diabetic control. This result highlights positive effect of naringin as an antioxidant, its role in apoptosis and also reverting the effects of organ damage in type 2 diabetes.

  6. Togetherness of the Multiple Diverticulosis of the First Part of the Duodenum with Neurofibromatosis Type I: A Case Report

    Directory of Open Access Journals (Sweden)

    Ozgur Turk

    2014-04-01

    Full Text Available Duedonal diverticulosis is common in clinical practice. Most of duedonal diverticulosis is located at the second part of duodenum; incidence is reported as 67%, incidence of third and forth part is %20. Multiple diverticulosis of the first part of the duodenum is a rare case. There is not any knowledge togetherness of neurofibromatosis type 1 and duedonal diverticulosis. Here we reported incidentally diagnosed multiple diverticulosis of duodenum that is located in the first part in a neurofibromatosis type 1 patient with multiple neurofibromatosis nodules. Neurofibromatosis could affect various organs. Along the digestive system carcinoid tumors and neuroendocrine tumors are more encountered diseases. Endoscopic examinations and abdominal imaging may be useful for the diagnosis of gastrointestinal coexisting disease in neurofibromatosis type 1 . In conclusion neurofibromatosis type 1 could affect multiple systems and it should evaluate carefully.

  7. Missed doses of oral antihyperglycemic medications in US adults with type 2 diabetes mellitus: prevalence and self-reported reasons.

    Science.gov (United States)

    Vietri, Jeffrey T; Wlodarczyk, Catherine S; Lorenzo, Rose; Rajpathak, Swapnil

    2016-09-01

    Adherence to antihyperglycemic medication is thought to be suboptimal, but the proportion of patients missing doses, the number of doses missed, and reasons for missing are not well described. This survey was conducted to estimate the prevalence of and reasons for missed doses of oral antihyperglycemic medications among US adults with type 2 diabetes mellitus, and to explore associations between missed doses and health outcomes. The study was a cross-sectional patient survey. Respondents were contacted via a commercial survey panel and completed an on-line questionnaire via the Internet. Respondents provided information about their use of oral antihyperglycemic medications including doses missed in the prior 4 weeks, personal characteristics, and health outcomes. Weights were calculated to project the prevalence to the US adult population with type 2 diabetes mellitus. Outcomes were compared according to number of doses missed in the past 4 weeks using bivariate statistics and generalized linear models. Approximately 30% of adult patients with type 2 diabetes mellitus reported missing or reducing ≥1 dose of oral antihyperglycemic medication in the prior 4 weeks. Accidental missing was more commonly reported than purposeful skipping, with forgetting the most commonly reported reason. The timing of missed doses suggested respondents had also forgotten about doses missed, so the prevalence of missed doses is likely higher than reported. Outcomes were poorer among those who reported missing three or more doses in the prior 4 weeks. A substantial number of US adults with type 2 diabetes mellitus miss doses of their oral antihyperglycemic medications.

  8. Inulin Supplementation Does Not Reduce Plasma Trimethylamine N-Oxide Concentrations in Individuals at Risk for Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Mary Elizabeth Baugh

    2018-06-01

    Full Text Available Trimethylamine N-oxide (TMAO is associated with type 2 diabetes (T2DM and increased risk of adverse cardiovascular events. Prebiotic supplementation has been purported to reduce TMAO production, but whether prebiotics reduce fasting or postprandial TMAO levels is unclear. Sedentary, overweight/obese adults at risk for T2DM (n = 18 were randomized to consume a standardized diet (55% carbohydrate, 30% fat with 10 g/day of either an inulin supplement or maltodextrin placebo for 6 weeks. Blood samples were obtained in the fasting state and hourly during a 4-h high-fat challenge meal (820 kcal; 25% carbohydrate, 63% fat; 317.4 mg choline, 62.5 mg betaine, 8.1 mg l-carnitine before and after the diet. Plasma TMAO and trimethylamine (TMA moieties (choline, l-carnitine, betaine, and γ-butyrobetaine were measured using isocratic ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS. There were no differences in fasting or postprandial TMAO or TMA moieties between the inulin and placebo groups at baseline (all p > 0.05. There were no significant changes in fasting or postprandial plasma TMAO or TMA moiety concentrations following inulin or placebo. These findings suggest that inulin supplementation for 6 weeks did not reduce fasting or postprandial TMAO in individuals at risk for T2DM. Future studies are needed to identify efficacious interventions that reduce plasma TMAO concentrations.

  9. Oxygen concentration diffusion analysis of lead-bismuth-cooled, natural-circulation reactor

    International Nuclear Information System (INIS)

    Ito, Kei; Sakai, Takaaki

    2001-11-01

    The feasibility study on fast breeder reactors in Japan has been conducted at JNC and related organizations. The Phase-I study has finished in March, 2001. During the Phase-I activity, lead-bismuth eutectic coolant has been selected as one of the possible coolant options and a medium-scale plant, cooled by a lead-bismuth natural circulation flow was studied. On the other side, it is known that lead-bismuth eutectic has a problem of structural material corrosiveness. It was found that oxygen concentration control in the eutectic plays an important role on the corrosion protection. In this report, we have developed a concentration diffusion analysis code (COCOA: COncentration COntrol Analysis code) in order to carry out the oxygen concentration control analysis. This code solves a two-dimensional concentration diffusion equation by the finite differential method. It is possible to simulate reaction of oxygen and hydrogen by the code. We verified the basic performance of the code and carried out oxygen concentration diffusion analysis for the case of an oxygen increase by a refueling process in the natural circulation reactor. In addition, characteristics of the oxygen control system was discussed for a different type of the control system as well. It is concluded that the COCOA code can simulate diffusion of oxygen concentration in the reactor. By the analysis of a natural circulation medium-scale reactor, we make clear that the ON-OFF control and PID control can well control oxygen concentration by choosing an appropriate concentration measurement point. In addition, even when a trouble occurs in the oxygen emission or hydrogen emission system, it observes that control characteristic drops away. It is still possible, however, to control oxygen concentration in such case. (author)

  10. Change in the electrical conductivity of SnO{sub 2} crystal from n-type to p-type conductivity

    Energy Technology Data Exchange (ETDEWEB)

    Villamagua, Luis, E-mail: luis.villamagua@tyndall.ie [Grupo de Fisicoquímica de Materiales, Universidad Técnica Particular de Loja, Apartado 11-01-608, Loja (Ecuador); Dipartimento di Ingegneria per l’Ambiente e il Territorio e Ingegneria Chimica, Università della Calabria, 87036 Rende (CS) (Italy); Stashans, Arvids [Grupo de Fisicoquímica de Materiales, Universidad Técnica Particular de Loja, Apartado 11-01-608, Loja (Ecuador); Lee, Po-Ming; Liu, Yen-Shuo; Liu, Cheng-Yi [Department of Chemical and Materials Engineering, National Central University, Jhong-Li, Taiwan (China); Carini, Manuela [Dipartimento di Ingegneria per l’Ambiente e il Territorio e Ingegneria Chimica, Università della Calabria, 87036 Rende (CS) (Italy)

    2015-05-01

    Highlights: • Switch from n-type to p-type conductivity in SnO{sub 2} has been studied. • Computational DFT + U method where used. • X-ray diffraction and X-ray photoelectron spectroscopy where used. • Al- and N-codoped SnO{sub 2} compound shows stable p-type conductivity. • Low resistivity (3.657 × 10{sup −1} Ω cm) has been obtained. • High carrier concentration (4.858 × 10{sup 19} cm{sup −3}) has been obtained. - Abstract: The long-sought fully transparent technology will not come true if the n region of the p–n junction does not get as well developed as its p counterpart. Both experimental and theoretical efforts have to be used to study and discover phenomena occurring at the microscopic level in SnO{sub 2} systems. In the present paper, using the DFT + U approach as a main tool and the Vienna ab initio Simulation Package (VASP) we reproduce both intrinsic n-type as well as p-type conductivity in concordance to results observed in real samples of SnO{sub 2} material. Initially, an oxygen vacancy (1.56 mol% concentration) combined with a tin-interstitial (1.56 mol% concentration) scheme was used to achieve the n-type electrical conductivity. Later, to attain the p-type conductivity, crystal already possessing n-type conductivity, was codoped with nitrogen (1.56 mol% concentration) and aluminium (12.48 mol% concentration) impurities. Detailed explanation of structural changes endured by the geometry of the crystal as well as the changes in its electrical properties has been obtained. Our experimental data to a very good extent matches with the results found in the DFT + U modelling.

  11. TEST and EVALUATION REPORT FOR THE HEDGEHOG-II PACKAGING SYSTEMS DOT-7A TYPE A CONTAINER

    International Nuclear Information System (INIS)

    KELLY, D.L.

    2003-01-01

    This report documents the US. Department of Transportation Specification 7A (DOT-7A) Type A compliance test and evaluation results for the Hedgehog-II packaging systems. The approved Hedgehog-II packaging configurations provide primary and secondary containment. The approved packaging configurations described within this report are designed to ship Type A quantities of radioactive materials, normal form. Contents may be in solid or liquid form. Liquids transported in the approved 1 L glass bottle assembly shall have a specific gravity of less than or equal to 1.6. Liquids transported in all other approved configurations shall have a specific gravity of less than or equal to 2.0. The solid contents, including packaging, are limited in weight to the gross weight of the as-tested liquids and bottles. The approved Hedgehog-II packaging configurations described in this report may be transported by air, and have been evaluated as meeting the applicable International Air Transport Association/International Civil Aviation Organization (IATA/ICAO) Dangerous Goods Regulations in addition to the DOT requirements

  12. Traffic exposure in a population with high prevalence type 2 diabetes - Do medications influence concentrations of C-reactive protein?

    International Nuclear Information System (INIS)

    Rioux, Christine L.; Tucker, Katherine L.; Brugge, Doug; Gute, David M.; Mwamburi, Mkaya

    2011-01-01

    Type 2 Diabetes (T2D) and particulate air pollution are associated with inflammatory dysregulation. We assessed the modifying effects of diabetes medications on the association of C-reactive protein (CRP), a marker of inflammation, and traffic exposure in adults with T2D (n = 379). CRP concentrations were significantly positively associated with residence ≤100 m of a roadway, >100 m and ≤200 m of a roadway and increased traffic density for individuals using insulin. For individuals using oral hypoglycemic medications (OHAs), CRP was significantly negatively associated with residence >100 m - ≤200 m of a roadway and multiple roadway exposure in an interaction model. Among people with diabetes, individuals on insulin appear to be most vulnerable to the effects of traffic exposure. Disease severity among insulin users may promote the pro-inflammatory response to traffic exposure, though diabetes medications may also modify the response. Possible anti-inflammatory effects of OHAs with traffic exposure merit further evaluation. - Highlights: →We examine traffic exposure in a population with high rates of Type 2 Diabetes. →Differences in CRP were evaluated by traffic levels, medication use and type. →Those on insulin had significantly higher CRP with traffic exposure. →Interaction models demonstrated lower CRP with traffic exposure and OHA use. →Diabetes medications may modify the response to traffic exposure. - Among people with diabetes, individuals on insulin appear to be most vulnerable to the effects of traffic exposure. Diabetes medications may modify the response to traffic.

  13. Serum bilirubin concentrations and incident coronary heart disease risk among patients with type 2 diabetes: the Dongfeng-Tongji cohort.

    Science.gov (United States)

    Wang, Jing; Wu, Xiaofen; Li, Yaru; Han, Xu; Hu, Hua; Wang, Fei; Yu, Caizheng; Li, Xiulou; Yang, Kun; Yuan, Jing; Yao, Ping; Miao, Xiaoping; Wei, Sheng; Wang, Youjie; Chen, Weihong; Liang, Yuan; Guo, Huan; Yang, Handong; Wu, Tangchun; Zhang, Xiaomin; He, Meian

    2017-03-01

    Elevated serum bilirubin levels are associated with decreased coronary heart disease (CHD) risk in cross-sectional studies among diabetic patients, but prospective evidence is limited. We investigated the relationship of serum bilirubin levels with incident CHD risk among type 2 diabetes patients. In a prospective study of 2918 type 2 diabetes embedded in the Dongfeng-Tongji cohort, serum total bilirubin (TBil), direct bilirubin (DBil), and indirect bilirubin (IBil) were measured at baseline. Cox proportional hazards models were used to examine the association between serum bilirubin levels and CHD risk. A total of 440 CHD cases were identified during 12,017 person-years of follow-up. Compared with extreme quartiles, the adjusted hazard ratio and 95% confidence interval of incident CHD were 0.74 (0.56-0.99) with P trend = 0.08 in IBil, while in TBil and DBil, the bilirubin-CHD associations were not significant. Moreover, serum TBil and IBil levels were interacted with drinking status on the risk of incident CHD (P interaction = 0.021 and 0.037, respectively), and the associations were evident in ever drinkers. In drinkers, when serum TBil or IBil concentrations increased 1 μmol/L, the CHD risk both decreased 6% (95% CIs 0.89-0.99 and 0.87-1.00, respectively). Serum IBil levels were marginally related to decreased incident CHD risk among type 2 diabetes. Drinking could potentially enhance the associations of serum TBil and DBil levels with incident CHD risk.

  14. δ- and δ'-shock wave types of singular solutions of systems of conservation laws and transport and concentration processes

    International Nuclear Information System (INIS)

    Shelkovich, V M

    2008-01-01

    This is a survey of some results and problems connected with the theory of generalized solutions of quasi-linear conservation law systems which can admit delta-shaped singularities. They are the so-called δ-shock wave type solutions and the recently introduced δ (n) -shock wave type solutions, n=1,2,..., which cannot be included in the classical Lax-Glimm theory. The case of δ- and δ'-shock waves is analyzed in detail. A specific analytical technique is developed to deal with such solutions. In order to define them, some special integral identities are introduced which extend the concept of weak solution, and the Rankine-Hugoniot conditions are derived. Solutions of Cauchy problems are constructed for some typical systems of conservation laws. Also investigated are multidimensional systems of conservation laws (in particular, zero-pressure gas dynamics systems) which admit δ-shock wave type solutions. A geometric aspect of such solutions is considered: they are connected with transport and concentration processes, and the balance laws of transport of 'volume' and 'area' to δ- and δ'-shock fronts are derived for them. For a 'zero-pressure gas dynamics' system these laws are the mass and momentum transport laws. An algebraic aspect of these solutions is also considered: flux-functions are constructed for them which, being non-linear, are nevertheless uniquely defined Schwartz distributions. Thus, a singular solution of the Cauchy problem generates algebraic relations between its components (distributions).

  15. Traffic exposure in a population with high prevalence type 2 diabetes - Do medications influence concentrations of C-reactive protein?

    Energy Technology Data Exchange (ETDEWEB)

    Rioux, Christine L., E-mail: christine.rioux@tufts.edu [Department of Public Health and Community Medicine, Tufts University, 136 Harrison Avenue, Boston, MA 02111 (United States); Tucker, Katherine L. [Department of Health Science, Northeastern University, Boston, MA (United States); Brugge, Doug [Department of Public Health and Community Medicine, Tufts University, 136 Harrison Avenue, Boston, MA 02111 (United States); Gute, David M. [Department of Civil and Environmental Engineering, Tufts University, Medford, MA (United States); Mwamburi, Mkaya [Department of Public Health and Community Medicine, Tufts University, 136 Harrison Avenue, Boston, MA 02111 (United States)

    2011-08-15

    Type 2 Diabetes (T2D) and particulate air pollution are associated with inflammatory dysregulation. We assessed the modifying effects of diabetes medications on the association of C-reactive protein (CRP), a marker of inflammation, and traffic exposure in adults with T2D (n = 379). CRP concentrations were significantly positively associated with residence {<=}100 m of a roadway, >100 m and {<=}200 m of a roadway and increased traffic density for individuals using insulin. For individuals using oral hypoglycemic medications (OHAs), CRP was significantly negatively associated with residence >100 m - {<=}200 m of a roadway and multiple roadway exposure in an interaction model. Among people with diabetes, individuals on insulin appear to be most vulnerable to the effects of traffic exposure. Disease severity among insulin users may promote the pro-inflammatory response to traffic exposure, though diabetes medications may also modify the response. Possible anti-inflammatory effects of OHAs with traffic exposure merit further evaluation. - Highlights: >We examine traffic exposure in a population with high rates of Type 2 Diabetes. >Differences in CRP were evaluated by traffic levels, medication use and type. >Those on insulin had significantly higher CRP with traffic exposure. >Interaction models demonstrated lower CRP with traffic exposure and OHA use. >Diabetes medications may modify the response to traffic exposure. - Among people with diabetes, individuals on insulin appear to be most vulnerable to the effects of traffic exposure. Diabetes medications may modify the response to traffic.

  16. Sandwich-type enzyme immunoassay for big endothelin-I in plasma: concentrations in healthy human subjects unaffected by sex or posture.

    Science.gov (United States)

    Aubin, P; Le Brun, G; Moldovan, F; Villette, J M; Créminon, C; Dumas, J; Homyrda, L; Soliman, H; Azizi, M; Fiet, J

    1997-01-01

    A sandwich-type enzyme immunoassay has been developed for measuring human big endothelin-1 (big ET-1) in human plasma and supernatant fluids from human cell cultures. Big ET-1 is the precursor of endothelin 1 (ET-1), the most potent vasoconstrictor known. A rabbit antibody raised against the big ET-1 COOH-terminus fragment was used as an immobilized antibody (anti-P16). The Fab' fragment of a monoclonal antibody (1B3) raised against the ET-1 loop fragment was used as the enzyme-labeled antibody, after being coupled to acetylcholinesterase. The lowest detectable value in the assay was 1.2 pg/mL (0.12 pg/well). The assay was highly specific for big ET-1, demonstrating no cross-reactivity with ET-1, big endothelin-2 (big ET-2), and big endothelin-3 (big ET-3). We used this assay to evaluate the effect of two different postural positions (supine and standing) on plasma big ET-1 concentrations in 11 male and 11 female healthy subjects. Data analysis revealed that neither sex nor body position influenced plasma big ET-1 concentrations. This assay should thus permit the detection of possible variations in plasma concentrations of big ET-1 in certain pathologies and, in association with ET-1 assay, make possible in vitro study of endothelin-converting enzyme activity in cell models. Such studies could clarify the physiological and clinical roles of this family of peptides.

  17. A study on the indoor radon concentrations in hospitals in the Shillong region, Meghalaya

    International Nuclear Information System (INIS)

    Sharma, Yubaraj; Maibam, Deveshwori; Saxena, Atul; Ram, Priya P.; Walia, Devesh

    2015-01-01

    In this paper, we report our findings on radon survey in indoor environment which consists of around 105 rooms in 8 major hospitals in Shillong region and also present experimental estimates on the associated annual effective doses and life-time fatality risks. The survey has been undertaken using LR-115 Type 2 detectors. Radon activity concentration values were found to range from 65.66 Bq.m -3 to 783.77 Bq.m -3 with an arithmetic mean value of 260.4±138.3 Bq.m -3 and a geometric mean value of 228.4±1.67 Bq.m -3 . Distribution analysis of the radon activity concentration measured at the hospital rooms has been carried out. Of the total rooms surveyed, 60% have radon concentration more than the ICRP prescribed lower limit of 200 Bq.m -3 and about 4% of the rooms higher than the upper limit of 600 Bq.m -3 . Floor-wise study has been done and a decrease in radon concentration with increase in floor-number has been observed. (author)

  18. Determination of Reportable Radionuclides for DWPF Sludge Batch 2 (Macro Batch 3)

    International Nuclear Information System (INIS)

    Bibler, N.E.

    2002-01-01

    The Waste Acceptance Product Specifications (WAPS) 1.2 require that ''The Producer shall report the inventory of radionuclides (in Curies) that have half-lives longer than 10 years and that are, or will be, present in concentrations greater than 0.05 percent of the total inventory for each waste type indexed to the years 2015 and 3115''. As part of the strategy to meet WAPS 1.2, the Defense Waste Processing Facility (DWPF) will report for each waste type, all radionuclides (with half-lives greater than 10 years) that have concentrations greater than 0.01 percent of the total inventory from time of production through the 1100 year period from 2015 through 3115. The initial listing of radionuclides to be included is based on the design-basis glass as identified in the Waste Form Compliance Plan (WCP) and Waste Form Qualification Report (WQR). However, it is required that this list be expanded if other radionuclides with half-lives greater than 10 years are identified that meet the greater than 0.01 percent criterion for Curie content

  19. Self-reported type 2 diabetes Mellitus is associated with abdominal obesity and poor perception of health in shift workers

    Directory of Open Access Journals (Sweden)

    Carine FRÖHLICH

    Full Text Available ABSTRACT Objective: To investigate factors that are associated with type 2 diabetes Mellitus in shift workers of a slaughterhouse in Southern Brazil. Methods: This cross-sectional study included 1,194 18- to 50-year-old workers of both sexes. The presence of type 2 diabetes Mellitus was self-reported and confirmed by the use of hypoglycemic drugs or insulin. The independent variables were sex, age, skin color, marital status, education level, family income, leisure time physical activity, smoking, and self-reported health and nutritional status (body mass index and waist circumference. Multivariate analysis was performed from an a priori conceptual model. Results: The prevalence of diabetes was 1.3% (95%CI=0.6-1.9. Type 2 diabetes Mellitus was associated with poor or regular self-reported health (OR=3.72; 95%CI=1.28-10.78 and level II abdominal obesity ³102 for men and ³88 for women (OR=5.76; 95%CI=1.07-29.10. Conclusion: The prevalence of type 2 diabetes Mellitus was low. Moreover, the study evidenced the importance of using waist circumference to surveil and screen for metabolic diseases, such as type 2 diabetes Mellitus, and to monitor the low quality of life in the study individuals given the poor self-perceived health of workers with the said disease.

  20. Type checking with open type functions

    DEFF Research Database (Denmark)

    Schrijvers, Tom; Jones, Simon Peyton; Chakravarty, Manual

    2008-01-01

    We report on an extension of Haskell with open type-level functions and equality constraints that unifies earlier work on GADTs, functional dependencies, and associated types. The contribution of the paper is that we identify and characterise the key technical challenge of entailment checking; an...

  1. Integrating measurements of indoor thoron and its progeny concentrations

    International Nuclear Information System (INIS)

    Zhuo, W.H.; Iida, T.; Hashiguchi, Y.

    2000-01-01

    In recent years, indoor surveys in Europe and Asia revealed that the dose contribution from thoron and its progeny can equal or even exceed that of radon and its progeny. For measuring thoron and its progeny, several methods had been reported. However, convenient, low-cost and time-integrating measuring methods which are suitable for large-scale surveys are still unavailable. To solve this problem, three integrating measuring methods with allyl diglycol carbonate plastic (CR-39) as detectors have recently been. The results indicated that they are suitable for estimating the indoor thoron and its progeny concentrations when the public exposure to thoron and its progeny is taken into account. Cup monitor - Former types of passive integrating 222 Rn and 220 Rn cup monitors had been reported. Recently, in order to improve the sensitivity of thoron detection, the air exchange rate between the inner and outer cup was enhanced, and the radius of the hemisphere was reduced to 37.5 mm. Furthermore, the procedure of detector exchange was made to be more convenient. Equilibrium-equivalent 222 Rn and 220 Rn concentrations monitor (EEC monitor) - The measuring system is composed of a monitor head and a diaphragm pump. The total weight of the system is less than 1.5 kg, which makes it portable. The construction of the monitor head and the measuring principle were also reported by the authors. Thoron progeny deposition rate monitor - The monitor is simply constituted a piece of CR-39 covered with thin sheets of absorbers. The thickness of the absorbers are adjusted to let only the α particles emitted from 212 Pb impinge on the detector. The concentrations of thoron progeny are estimated from the deposition rates, assuming that the deposition velocities of thoron progeny are constant in general dwellings. The improved cup monitor has higher sensitivity than former monitors, with a calibration factor of 1.59x10 -3 tracks·cm -2 (Bq·m -3 ·h) -1 for thoron. The accuracy of the ECC

  2. Vascular-type Ehlers-Danlos syndrome caused by a hitherto unknown genetic mutation: a case report

    Directory of Open Access Journals (Sweden)

    Kashizaki Fumihiro

    2013-02-01

    Full Text Available Abstract Introduction Vascular-type Ehlers-Danlos syndrome is an autosomal dominant disease that causes arterial spurting, intestinal perforation, uterine rupture and hemopneumothorax due to decreased production of type III collagen. The average age at death is 48 years old, and it is considered to be the most severe form of Ehlers-Danlos syndrome. We report the case of a 64-year-old Japanese woman and her 38-year-old daughter who were diagnosed with this disease. Case presentation A 64-year-old Japanese woman was referred to our hospital because of right anterior chest pain following cough and pharyngeal discomfort. Pleurisy was suspected due to the presence of right pleural effusion, so the next day she was referred to our department, where a detailed examination led to the diagnosis of hemothorax. The bleeding that caused the right hemothorax was difficult to control, so our patient was transferred to the Department of Thoracic Surgery for hemostasis control. Our patient’s personal history of uterine hemorrhage and skin ulcers, as well as the finding of skin fragility during surgery, were indicative of a weak connective tissue disease; therefore, after improvement of the hemothorax, a genetic analysis was performed. This revealed a heterozygous missense mutation in COL3A1, c.2411 G>T p.Gly804Val (exon 36. A detailed investigation conducted at a later date revealed that her daughter also had the same genetic mutation. This led to the diagnosis of vascular-type Ehlers-Danlos syndrome characterized by a new gene mutation. Conclusion We report a new genetic mutation associated with vascular-type Ehlers-Danlos syndrome. We present the clinical and imaging findings, and the disease and treatment course in this patient. We believe this information will be important in treating future cases of vascular-type Ehlers-Danlos syndrome in patients with this mutation.

  3. Simulation of a photo-solar generator for an optimal output by a parabolic photovoltaic concentrator of Stirling engine type

    Science.gov (United States)

    Kaddour, A.; Benyoucef, B.

    Solar energy is the source of the most promising energy and the powerful one among renewable energies. Photovoltaic electricity (statement) is obtained by direct transformation of the sunlight into electricity, by means of cells statement. Then, we study the operation of cells statement by the digital simulation with an aim of optimizing the output of the parabolic concentrator of Stirling engine type. The Greenius software makes it possible to carry out the digital simulation in 2D and 3D and to study the influence of the various parameters on the characteristic voltage under illumination of the cell. The results obtained enabled us to determine the extrinsic factors which depend on the environment and the intrinsic factors which result from the properties of materials used.

  4. Low plasma adiponectin concentrations do not predict weight gain in humans

    DEFF Research Database (Denmark)

    Vozarova, Barbora; Stefan, Norbert; Lindsay, Robert S

    2002-01-01

    Low concentrations of plasma adiponectin, the most abundant adipose-specific protein, are observed in obese individuals and predict the development of type 2 diabetes. Administration of adiponectin to rodents prevented diet-induced weight gain, suggesting a potential etiologic role of hypoadipone......Low concentrations of plasma adiponectin, the most abundant adipose-specific protein, are observed in obese individuals and predict the development of type 2 diabetes. Administration of adiponectin to rodents prevented diet-induced weight gain, suggesting a potential etiologic role...... of hypoadiponectinemia in the development of obesity. Our aim was to prospectively examine whether low plasma adiponectin concentrations predict future weight gain in Pima Indians, explaining the predictive effect of adiponectin on the development of type 2 diabetes. We measured plasma adiponectin concentrations in 219...... nondiabetic Pima Indians (112 M/107 F, age 31 +/- 9 years, body weight 96 +/- 20 kg [mean +/- SD]) in whom body weight and height were measured and BMI calculated at baseline and follow-up. Cross-sectionally, plasma adiponectin concentrations were negatively associated with body weight (r = -0.28, P = 0...

  5. Direct determination of atom and radical concentrations in thermal reactions of hydrocarbons and other gases. Progress report, December 1, 1981-December 31, 1982

    International Nuclear Information System (INIS)

    Skinner, G.B.; Rao, V.S.; Wood, D.R.

    1983-01-01

    This is the seventh annual progress report on this project. During the period covered by the first six reports (June 1976 through December 1980) a shock tube and optical systems to measure H, D and O atom concentrations were built and fully characterized. The performance of our microwave discharge lamps were defined by numerous high-resolution spectroscopic profiles, while empirical calibrations were also made for all three of the above species. H, D and O atom concentrations were measured in gas mixtures containing H 2 , D 2 , O 2 , CD 4 , C 2 H 6 , C 2 D 6 , C 3 H 8 and C 3 D 8 in various proportions, and rate constants of several elementary reactions were deduced from the data. During the period covered by this report (December 1, 1981 to December 31, 1982) we have made kinetic modelling calculations to correlate H, D and O atom concentrations measured in shock-heated mixtures of C 2 H 6 -O 2 -Ar, C 2 D 6 -O 2 -Ar, C 3 H 8 -O 2 -Ar and C 3 D 8 -O 2 -Ar. These computations are difficult because there are several reactions for which rate constants are not known, so that it is necessary to do many calculations to completely optimize the results. Consequently, work is still going on with these calculations. We have completed an extensive series of measurements of H and D atom concentrations in pyrolysis experiments of benzene, toluene and neopentane and deuterium analogs, that have led to rate constants for the initial dissociation of these compounds, and for the reaction of H atoms with benzene and toluene

  6. Fiber-Type Random Laser Based on a Cylindrical Waveguide with a Disordered Cladding Layer.

    Science.gov (United States)

    Zhang, Wei Li; Zheng, Meng Ya; Ma, Rui; Gong, Chao Yang; Yang, Zhao Ji; Peng, Gang Ding; Rao, Yun Jiang

    2016-05-25

    This letter reports a fiber-type random laser (RL) which is made from a capillary coated with a disordered layer at its internal surface and filled with a gain (laser dye) solution in the core region. This fiber-type optical structure, with the disordered layer providing randomly scattered light into the gain region and the cylindrical waveguide providing confinement of light, assists the formation of random lasing modes and enables a flexible and efficient way of making random lasers. We found that the RL is sensitive to laser dye concentration in the core region and there exists a fine exponential relationship between the lasing intensity and particle concentration in the gain solution. The proposed structure could be a fine platform of realizing random lasing and random lasing based sensing.

  7. Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Young Larry

    2011-03-01

    Full Text Available Abstract Introduction Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus erythematosus complicated by type 4 renal tubular acidosis who did not do poorly. Case presentation A 44-year-old Hispanic woman developed a non-anion gap hyperkalemic metabolic acidosis consistent with type 4 renal tubular acidosis while being treated in the hospital for recently diagnosed systemic lupus erythematosus with multi-organ involvement. She responded well to treatment with corticosteroids, hydroxychloroquine and mycophenolate mofetil. Normal renal function was achieved prior to discharge and remained normal at the patient's one-month follow-up examination. Conclusion This case increases awareness of an uncommon association between systemic lupus erythematosus and type 4 renal tubular acidosis and suggests a positive impact of early diagnosis and appropriate immunosuppressive treatment on the patient's outcome.

  8. Concentration of gallium in the Permo-Carboniferous coals of China

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Cunliang; Qin, Shenjun; Yang, Yinchao; Li, Yanheng; Lin, Mingyue [Hebei University of Engineering, Handan (China)

    2009-10-15

    Gallium is widely used in electronic industry and its current price is about 500 US dollars per kilogram. It has been found that its contents are very high in Permo-Carboniferous coal of China. In order to look for valuable associated gallium deposits in coal, gallium contents of 177 coal samples were determined by using inductively coupled plasma-mass spectrometry (ICP-MS) and the data of 873 coal samples from Chinese Permo-Carboniferous coalfields were collected. The results show that the average gallium concentration of Chinese Permo-Carboniferous coals is 15.49{mu}g{center_dot}g{sup -1}. There are two concentration types of gallium in Chinese Permo-Carboniferous coals: one type is that gallium has enriched to an ore deposit, and another type is that gallium is locally enriched in coal seams, but has not formed a valuable associated gallium ore deposit. The gallium concentration in Chinese Permo-Carboniferous coal may have several different sources: concentration in sedimentation stage, magmatic hydrothermal inputs and low-temperature hydrothermal fluids.

  9. Performance investigation of a concentrating photovoltaic/thermal system with transmissive Fresnel solar concentrator

    International Nuclear Information System (INIS)

    Feng, Chaoqing; Zheng, Hongfei; Wang, Rui; Ma, Xinglong

    2016-01-01

    Highlights: • A common design method of a cycloidal transmissive Fresnel solar concentrator was presented. • The gallium arsenide high concentrated solar was used as the receiver. • High efficiency of electric generating could be achieved at noon. • Fresnel solar concentrator was studied and compared in hazy weather and clear weather. - Abstract: A design method of a cycloidal transmissive Fresnel solar concentrator which can provide a certain width focal line was presented in this study. Based on the optical principle of refraction, the dimensions of each wedge-shaped element of Fresnel lens are calculated. An optical simulation has been done to obtain the optical efficiency of the concentrator for different tracking error and axial incidence angle. It has been found that about 80% of the incident sunlight can still be gathered by the absorber when the tracking error is within 0.7°. When the axial angle of incidence is within 10°, it almost has no influence to the receiving rate. The concentrating photovoltaic/thermal system with transmissive Fresnel solar concentrator has been designed in this paper. Take the gallium arsenide high concentrated battery as the receiver, experimental research about cylindrical Fresnel concentrating photovoltaic/thermal system is undertaken in the real sky. Main parameters are tested such as the temperature distribution on receiver, electric energy and thermal energy outputs of concentrating photovoltaic/thermal system, the efficiency of multipurpose utilization of electric and heat, and so on. The test results in clear weather show that maximum electric generating efficiency is about 18% at noon, the maximum heat receiving rate of cooling water is about 45%. At noon time (11:00–13:00), the total efficiency of thermal and electricity can reach more than 55%. Performance of this concentrating photovoltaic/thermal system with transmissive Fresnel solar concentrator is studied and compared in two types typical weather, hazy

  10. Predictors of Airborne Endotoxin Concentrations in Inner City Homes

    Science.gov (United States)

    Mazique, D; Diette, GB; Breysse, PN; Matsui, EC; McCormack, MC; Curtin-Brosnan, J; Williams, D; Peng, RD; Hansel, NN

    2011-01-01

    Few studies have assessed in-home factors which contribute to airborne endotoxin concentrations. In 85 inner-city Baltimore homes, we found no significant correlation between settled dust and airborne endotoxin concentrations. Certain household activities and characteristics, including frequency of dusting, air conditioner use and type of flooring, explained 36–42% of the variability of airborne concentrations. Measurements of both airborne and settled dust endotoxin concentrations may be needed to fully characterize domestic exposure in epidemiologic investigations. PMID:21429483

  11. Nicotine concentration of e-cigarettes used by adolescents.

    Science.gov (United States)

    Morean, Meghan E; Kong, Grace; Cavallo, Dana A; Camenga, Deepa R; Krishnan-Sarin, Suchitra

    2016-10-01

    E-cigarettes are popular among youth, but little is known about the nicotine concentrations of e-liquids used by adolescents. In Spring, 2014, we conducted cross-sectional surveys in four Connecticut high schools and two middle schools. Among past-30-day e-cigarette users (n=513, 45% female, mean age 15.9 [SD=1.4]), we examined what nicotine concentration adolescents typically used in their e-cigarettes (range 0-30mg/mL and "I don't know"). We first examined whether age, sex, smoking status, e-cigarette use frequency, and/or e-cigarette acquisition source were associated with using nicotine-free e-liquid, nicotine e-liquid, or not knowing the e-liquid nicotine concentration. Among nicotine users (n=185), we then examined whether the aforementioned variables were associated with using higher nicotine concentrations. Adolescents reported using nicotine-free e-liquid (28.5%), nicotine e-liquid (37.4%), or not knowing their e-liquid nicotine concentration (34.1%). Nicotine users comprised more smokers and heavier e-cigarette users compared to nicotine-free e-liquid users and those who did not know their nicotine concentration. Nicotine users also comprised more males and were more likely to purchase e-cigarettes online or from tobacco shops compared to those who did not know their nicotine concentration. Among nicotine users, cigarette smoking, male sex, and purchasing e-cigarettes from tobacco shops predicted using higher nicotine concentrations. Adolescents reported using e-liquids with variable nicotine concentrations. Smokers, males, and those who purchased their own e-cigarettes reported using the highest nicotine levels. Of concern, many adolescents were unaware of the nicotine concentration in their e-liquid, raising concerns about inadvertent nicotine exposure among youth. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  12. Report of the specialized detector group

    International Nuclear Information System (INIS)

    Witherell, M.S.

    1984-01-01

    The Specialized Detector Group was assigned the task of studying the types of detectors, other than general purpose detectors, that might be suitable for the SSC. At the start of the Snowmass workshop, a number of physics topics were identified which could call for a specialized detector. The modest size of the specialized detector group dictated that we concentrate on a few of these detectors, and not try to consider all candidates. Subgroups were formed for each type of detector, and they worked completely independently on their very different problems. The members of a subgroup were also members of the corresponding group within the Physics area. Because of the wide variety of problems faced by the various subgroups, the detectors will be described in separate papers within these proceedings (some of them within the Physics group reports). Thus, this report gives a summary of these designs and discusses some general considerations

  13. Inhibition of biofilm formation by D-tyrosine: Effect of bacterial type and D-tyrosine concentration.

    Science.gov (United States)

    Yu, Cong; Li, Xuening; Zhang, Nan; Wen, Donghui; Liu, Charles; Li, Qilin

    2016-04-01

    D-Tyrosine inhibits formation and triggers disassembly of bacterial biofilm and has been proposed for biofouling control applications. This study probes the impact of D-tyrosine in different biofilm formation stages in both G+ and G- bacteria, and reveals a non-monotonic correlation between D-tyrosine concentration and biofilm inhibition effect. In the attachment stage, cell adhesion was studied in a flow chamber, where D-tyrosine caused significant reduction in cell attachment. Biofilms formed by Pseudomonas aeruginosa and Bacillus subtilis were characterized by confocal laser scanning microscopy as well as quantitative analysis of cellular biomass and extracellular polymeric substances. D-Tyrosine exhibited strong inhibitive effects on both biofilms with an effective concentration as low as 5 nM; the biofilms responded to D-tyrosine concentration change in a non-monotonic, bi-modal pattern. In addition, D-tyrosine showed notable and different impact on EPS production by G+ and G- bacteria. Extracellular protein was decreased in P. aeruginosa biofilms, but increased in those of B. subtilis. Exopolysaccharides production by P. aeruginosa was increased at low concentrations and reduced at high concentrations while no impact was found in B. subtilis. These results suggest that distinct mechanisms are at play at different D-tyrosine concentrations and they may be species specific. Dosage of D-tyrosine must be carefully controlled for biofouling control applications. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Multidisciplinary study of radionuclides and heavy-metal concentrations in wildlife on phosphate-mined and reclaimed lands. Final report

    International Nuclear Information System (INIS)

    Pritchard, P.C.H.; Bloodwell, J.M.

    1986-11-01

    The phosphate-rich mineral deposits of central Florida tend to exhibit background radiation levels that are elevated due to the uranium and its decay products found in association with the ore. The report documents radioactivity levels in two groups of animals that had heretofore not been examined by other investigators -- aquatic reptiles (American alligators, softshell turtles, and Florida cooter turtles) and terrestrial mammals (armadillos), based on the criterion that these species have significant proportions of their mass comprised of bony tissue likely to show elevated concentrations of radium. The alligator bones contained only low concentrations of radium, and there were no significant differences between alligators collected from mined, mineralized-unmined, or unmineralized land. Whether the levels of radium in the bones of the turtles represents a hazard to the health of these long-lived animals or to humans who may consume their flesh is unclear

  15. 27 CFR 25.296 - Record of beer concentrate.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Record of beer concentrate..., DEPARTMENT OF THE TREASURY LIQUORS BEER Records and Reports § 25.296 Record of beer concentrate. (a) Daily records. A brewer who produces concentrate or reconstitutes beer shall maintain daily records which...

  16. Impact of hemoglobin on plasma pro-B-type natriuretic peptide concentrations in the general population

    DEFF Research Database (Denmark)

    Nybo, Mads; Benn, Marianne; Mogelvang, Rasmus

    2007-01-01

    , the impact of hemoglobin status on proBNP concentrations has not been established in the general population. METHODS: In the 4th examination in the Copenhagen City Heart Study, we performed a nested case-control study of 6238 individuals from a Danish general population. Of these, 3497 randomly selected...... participants also underwent an echocardiographic examination. The population was stratified into groups depending on health and hemoglobin status. Correlations between hemoglobin and proBNP concentrations were examined by simple and multiple regression analyses, adjusted for variables known to influence...... the proBNP plasma concentration. RESULTS: The mean proBNP concentration was increased 1.7-fold in the group with anemia vs the nonanemic group [mean (SD) 42 (45) pmol/L vs 25 (29) pmol/L, P hemoglobin on pro...

  17. Equipment and building structures ageing management for WWER type NPPs

    International Nuclear Information System (INIS)

    Mayboroda, O.

    2001-01-01

    This report presents the working group 'Equipment and building structures ageing management for WWER type NPPs' activities. The analysis of experience in ageing management, recommendations for regulatory guidelines on ageing management, investigation of case studies, definition suitable communication channels among regulators for ageing related data are given. Analyses of water chemistry, inspection data (safety margins criteria), plugging criteria, volume and time of ECT implementation in all WWER countries are presented. The results of Working group activity show that it is advisable to concentrate efforts on: set up the permanent communication channel among regulators, collection of regulatory criteria for WWER type NPP key components based on understanding of ageing mechanisms and data collection

  18. Concentration fluctuations in gas releases by industrial accidents. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, M.; Chatwin, P.C.; Joergensen, H.E.; Mole, N.; Munro, R.J.; Ott, S.

    2002-05-01

    The COFIN project studied existing remote-sensing Lidar data on concentration fluctuations in atmospheric dispersion from continuous sources at ground level. Fluctuations are described by stochastic models developed by a combination of statistical analyses and surface-layer scaling. The statistical moments and probability density distribution of the fluctuations are most accurately determined in a frame of reference following the instantaneous plume centreline. The spatial distribution of these moments is universal with a gaussian core and exponential tails. The instantaneous plume width is fluctuating with a log-normal distribution. The position of the instantaneous plume centre-line is modelled by a normal distribution and a Langevin equation, by which the meander effect on the time-averaged plume width is predicted. Fixed-frame statistics are modelled by convolution of moving-frame statistics and the probability distribution for the plume centreline. The distance-neighbour function generalized for higher-order statistics has a universal exponential shape. Simulation tools for concentration fluctuations have been developed for either multiple correlated time series or multi-dimensional fields. These tools are based on Karhunen-Loeve expansion and Fourier transformations using iterative or correlation-distortion techniques. The input to the simulation is the probability distribution of the individual processes, assumed stationary, and the cross-correlations of all signal combinations. The use in practical risk assessment is illustrated by implementation of a typical heavy-gas dispersion model, enhanced for prediction and simulation of concentration fluctuations. (au)

  19. Measurements of thoron and radon progeny concentrations in Beijing, China

    International Nuclear Information System (INIS)

    Zhang Lei; Liu Cuihong; Guo Qiuju

    2008-01-01

    It has been reported that thoron levels in China are above the world average and may therefore make a significant contribution to the natural background radiation dose. We therefore conducted a pilot study of concentrations of both thoron and radon progeny during the spring of 2006 in the Beijing area, China. A new type of portable 24 h integrating monitor with a CR-39 detector was used during the survey. Seventy dwellings and eight outdoor sites were measured during the survey. For country houses built of red bricks and slurry, the average equilibrium equivalent concentrations (EEC) of thoron and radon were 1.02 ± 0.48 and 16.41 ± 9.02 Bq m -3 , respectively, whereas for city dwellings built of cement blocks and floor slabs, the results were 0.48 ± 0.47 and 11.50 ± 6.99 Bq m -3 for thoron and radon, respectively. For outdoor air, concentrations of thoron and radon progeny were 0.29 ± 0.28 and 7.05 ± 2.68 Bq m -3 , respectively. Radiation exposures from thoron and radon progeny were also evaluated; the ratio of dose contribution from thoron progeny to that of radon progeny was evaluated to be 28% and 17% in country houses and city dwellings, respectively. (note)

  20. Self-reported sitting time and prevalence of erectile dysfunction in Japanese patients with type 2 diabetes mellitus: The Dogo Study.

    Science.gov (United States)

    Furukawa, Shinya; Sakai, Takenori; Niiya, Tetsuji; Miyaoka, Hiroaki; Miyake, Teruki; Yamamoto, Shin; Kanzaki, Sayaka; Maruyama, Koutatsu; Tanaka, Keiko; Ueda, Teruhisa; Senba, Hidenori; Torisu, Masamoto; Minami, Hisaka; Tanigawa, Takeshi; Matsuura, Bunzo; Hiasa, Yoichi; Miyake, Yoshihiro

    2017-01-01

    No evidence exists regarding the association between sitting time and erectile dysfunction (ED) among patients with type 2 diabetes mellitus. The aim of this study was to evaluate the association between self-reported sitting time and ED among patients with type 2 diabetes mellitus. Study subjects were 430 male Japanese patients with type 2 diabetes mellitus (mean age, 60.5years). A self-administered questionnaire was used to collect information on the variables under study. The study subjects were asked about time spent sitting during typical 24-hour periods over the past 12months. Subjects were divided into four groups according to self-reported sitting time: 1) 2) 5-7hours, 3) 7-9hours, and 4) ≥9hours. ED was defined as present when a subject had a Sexual Health Inventory for Men score type 2 diabetes, current smoking, current drinking, hypertension, coronary artery disease, stroke, glycated hemoglobin, walking habit, and diabetic neuropathy. The prevalence values of moderate to severe ED and severe ED were 36.1% and 49.8%. At least 9hours sitting was independently positively associated with severe ED but not moderate to severe ED; the adjusted OR was 1.84 (95% CI: 1.06-3.33). In the multivariate model, there was a statistically significant inverse exposure-response relationship between the self-reported sitting time and severe ED (p for trend=0.029). Self-reported sitting time may be positively associated with ED in Japanese patients with type 2 diabetes mellitus. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Usher syndrome Type I in an adult Nepalese male: a rare case report.

    Science.gov (United States)

    Sahu, Sabin; Singh, Sanjay Kumar

    2017-07-01

    Usher syndrome, also known as retinitis pigmentosa-dysacusis syndrome, is an extremely rare genetic disorder, characterized by retinitis pigmentosa (RP) and congenital sensorineural hearing loss. It has been estimated to account for 3-6% of the congenitally deaf population, upto 8-33% of individuals with RP and half of all cases with combined deafness and blindness (Vernon M,1969; Boughman JA et al,1983). The prevalence of Usher syndrome have been reported to range from 3.5 to 6.2 per 100,000 in different populations (Vernon M,1969; Boughman JA et al,1983; Yan D et al, 2010). We report a case of Usher syndrome type I in an adult Nepalese male with typical congenital profound hearing loss, and night blindness secondary to retinitis pigmentosa. © NEPjOPH.

  2. 1988 Hanford riverbank springs characterization report

    International Nuclear Information System (INIS)

    Dirkes, R.L.

    1990-12-01

    This reports presents the results of a special study undertaken to characterize the riverbank springs (i.e., ground-water seepage) entering the Columbia River along the Hanford Site. Radiological and nonradiological analyses were performed. River water samples were also analyzed from upstream and downstream of the Site as well as from the immediate vicinity of the springs. In addition, irrigation return water and spring water entering the river along the shoreline opposite Hanford were analyzed. Hanford-origin contaminants were detected in spring water entering the Columbia River along the Hanford Site. The type and concentrations of contaminants in the spring water were similar to those known to exist in the ground water near the river. The location and extent of the contaminated discharges compared favorably with recent ground-water reports and predictions. Spring discharge volumes remain very small relative to the flow of the Columbia. Downstream river sampling demonstrates the impact of ground-water discharges to be minimal, and negligible in most cases. Radionuclide concentrations were below US Department of Energy Derived Concentration Guides (DCGs) with the exception 90 Sr near the 100-N Area. Tritium, while below the DCG, was detected at concentrations above the US Environmental Protection Agency drinking water standards in several springs. All other radionuclide concentrations were below drinking water standards. Nonradiological contaminants were generally undetectable in the spring water. River water contaminant concentrations, outside of the immediate discharge zones, were below drinking water standards in all cases. 19 refs., 5 figs., 12 tabs

  3. Effect of soil surface management on radiocesium concentrations in apple orchard and fruit

    International Nuclear Information System (INIS)

    Kusaba, Shinnosuke; Matsuoka, Kaori; Abe, Kazuhiro

    2016-01-01

    We investigated the effect of soil surface management on radiocesium accumulation in an apple orchard in Fukushima Prefecture over 4 years after Tokyo Electric Power Company’s Fukushima Daiichi nuclear power plant accident in mid-March 2011. Different types of soil surface management such as clean cultivation, intertillage management, intertillage with bark compost application, sod culture, and zeolite application were employed. The radiocesium concentrations in soil were higher in the surface layer (0–5 cm) than in the other layers. The radiocesium concentration in the surface layer soil with sod culture in 2014 increased non-significantly compared with that observed in 2011. The radiocesium concentration in the mid-layer soil (5–15 cm) managed with intertillage was higher than that in soil managed using other types of management. The radiocesium amount in the organic matter on the soil surface was the highest in sod culture, and was significantly lower in the management with intertillage. The radiocesium concentration in fruit decreased exponentially during the 4 years in each types of soil surface management. The decrease in radiocesium concentration showed similar trends with each type of soil surface management, even if the concentration in each soil layer varied according to the management applied. Furthermore, intertillage with bark compost application did not affect the radiocesium concentration in fruit. These results suggest that the soil surface management type that affected the radiocesium distribution in the soil or the compost application with conventional practice did not affect its concentration in fruit of apple trees for at least 4 years since the nuclear power plant accident, at a radiocesium deposition level similar to that recorded in Fukushima City. (author)

  4. Concentration control in an isotope separation plant; Regulation des concentrations dans une usine de separation isotopique

    Energy Technology Data Exchange (ETDEWEB)

    Jacques, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    Concentration control is examined for the case of a gaseous diffusion plant for uranium isotope separation. The effects of various typical perturbations are described and adequate systems of corrective actions are determined according to selected criteria. (author) [French] On considere une installation de separation des isotopes de l'uranium par diffusion gazeuse. On etudie les effets sur les concentrations isotopiques de diverses perturbations type donnees a l'avance et on determine le systeme d'actions correctives qui permet de reduire ces effets d'apres un critere d'efficacite donne. (auteur)

  5. Plasma fibronectin concentrations in patients with liver diseases

    DEFF Research Database (Denmark)

    Gluud, C; Dejgaard, A; Clemmensen, I

    1983-01-01

    age- and sex-matched healthy controls in patients with chronic persistent or chronic active hepatitis (n = 7), primary biliary cirrhosis (n = 8), alcoholic fatty liver (n = 9), alcoholic hepatitis (n = 10), and alcoholic cirrhosis (n = 16). Patients with acute viral hepatitis (type A (n = 2); type B...... (n = 7); type non A, non B (n = 1] had significantly (P less than 0.01) raised plasma fibronectin concentrations (median 506 mg/l (range 339-804] compared to controls (median 399 mg/l (range 304-462]. Morbidly obese patients with fatty liver (n = 11) had significantly (P less than 0.001) raised......Plasma, obtained just prior to diagnostic liver biopsy in 71 patients with various liver diseases, was examined by electroimmunoassay using immunoglobulin against human fibronectin and purified plasma fibronectin as standard. The plasma fibronectin concentration was not significantly different from...

  6. Evaluation of cage micro-environment of mice housed on various types of bedding materials.

    Science.gov (United States)

    Smith, Ellen; Stockwell, Jason D; Schweitzer, Isabelle; Langley, Stephen H; Smith, Abigail L

    2004-07-01

    A variety of environmental factors can affect the outcomes of studies using laboratory rodents. One such factor is bedding. Several new bedding materials and processing methods have been introduced to the market in recent years, but there are few reports of their performance. In the studies reported here, we have assessed the cage micro-environment (in-cage ammonia levels, temperature, and humidity) of mice housed on various kinds of bedding and their combinations. We also compared results for bedding supplied as Nestpaks versus loose bedding. We studied C57BL/6J mice (commonly used) and NOD/LtJ mice (heavy soilers) that were maintained, except in one study, in static duplex cages. In general, we observed little effect of bedding type on in-cage temperature or humidity; however, there was considerable variation in ammonia concentrations. The lowest ammonia concentrations occurred in cages housing mice on hardwood bedding or a mixture of corncob and alpha cellulose. In one experiment comparing the micro-environments of NOD/LtJ male mice housed on woodpulp fiber bedding in static versus ventilated caging, we showed a statistically significant decrease in ammonia concentrations in ventilated cages. Therefore, our data show that bedding type affects the micro-environment in static cages and that effects may differ for ventilated cages, which are being used in vivaria with increasing frequency. Copyright 2004 American Association for Laboratory Animal Science

  7. Reported Influences on Restaurant-Type Food Selection Decision Making in a Grocery Store Chain.

    Science.gov (United States)

    Bachman, Jessica Lynne; Arigo, Danielle

    2018-06-01

    To examine food decision-making priorities for restaurant-type foods at grocery stores and determine whether adding calorie information, as required by federal menu labeling laws, affected decision-making priorities. Natural experiment: intervention and control groups with baseline and follow-up. Regional grocery store chain with 9 locations. Participants (n = 393; mean age, 54.8 ± 15.1 years) were primarily women (71%) and Caucasian (95%). Data were collected before and after calorie information was added to restaurant-type foods at 4 intervention locations. Primary influencers of food selection decision making for restaurant-type foods and frequency of use of nutrition information. Quantitative analysis examined the top 3 influencers of food selections and chi-square goodness of fit test determined whether the calorie labeling intervention changed food decision-making priorities. Qualitative data were used to describe responses. Taste, cost, and convenience were the most frequently reported influencers of restaurant-type food selections; 20% of participants rated calories as influential. Calorie labeling did not affect food selection decision making; 16% of participants in intervention stores noticed calorie labels. Qualitative explanations confirmed these findings. Menu labeling laws increase access to calorie information; however, use of this information is limited. Additional interventions are needed to encourage healthier restaurant-type food selections in grocery stores. Copyright © 2018 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  8. Three Case Reports of Successful Vibration Therapy of the Plantar Fascia for Spasticity Due to Cerebral Palsy-Like Syndrome, Fetal-Type Minamata Disease.

    Science.gov (United States)

    Usuki, Fusako; Tohyama, Satsuki

    2016-04-01

    Fetal-type Minamata disease is caused by the exposure to high concentrations of methylmercury in the fetal period and shows cerebral palsy-like clinical features. Relief of spasticity is a major task of rehabilitation to improve their activities of daily living. Here we report the effect of long-term vibration therapy on bilateral lower-limb spasticity in 3 patients with fetal-type Minamata disease. We used a simple, inexpensive, and noninvasive approach with hand-held vibration massagers, which were applied to the plantar fascia at 90 Hz for 15 minutes. The effect was observed soon after the first treatment and resulted in better performance of the repetitive facilitation. Vibration therapy for 1 year improved Modified Ashworth Scale for the ankle flexors in 2 cases. The labored gait improved and gait speed increased in another case. Continued vibration therapy for another 1 year further improved Modified Ashworth Scale score and range of motion of ankle dorsiflexion in 1 case. This case showed the decreased amplitude of soleus H-reflex after the 15-minute vibration therapy, suggesting that α-motor neuron excitability was suppressed. Vibration therapy using a hand-held vibration massager may offer safe and effective treatment for lower-limb spasticity in patients with chronic neurological disorders.

  9. Real-time monitoring of sucrose, sorbitol, d-glucose and d-fructose concentration by electromagnetic sensing.

    Science.gov (United States)

    Harnsoongnoen, Supakorn; Wanthong, Anuwat

    2017-10-01

    Magnetic sensing at microwave frequencies for real-time monitoring of sucrose, sorbitol, d-glucose and d-fructose concentrations is reported. The sensing element was designed based on a coplanar waveguide (CPW) loaded with a split ring resonator (SRR), which was fabricated on a DiClad 880 substrate with a thickness of 1.6mm and relative permittivity (ε r ) of 2.2. The magnetic sensor was connected to a Vector Network Analyzer (VNA) and the electromagnetic interaction between the samples and sensor was analyzed. The magnitude of the transmission coefficient (S 21 ) was used as an indicator to detect the solution sample concentrations ranging from 0.04 to 0.20g/ml. The experimental results confirmed that the developed system using microwaves for the real-time monitoring of sucrose, sorbitol, d-glucose and d-fructose concentrations gave unique results for each solution type and concentration. Moreover, the proposed sensor has a wide dynamic range, high linearity, fast operation and low-cost. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Effects of intraperitoneal insulin versus subcutaneous insulin administration on sex hormone-binding globulin concentrations in patients with type 1 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    M Boering

    2016-06-01

    Full Text Available Aims Elevated sex hormone-binding globulin (SHBG concentrations have been described in patients with type 1 diabetes mellitus (T1DM, probably due to low portal insulin concentrations. We aimed to investigate whether the route of insulin administration, continuous intraperitoneal insulin infusion (CIPII, or subcutaneous (SC, influences SHBG concentrations among T1DM patients. Methods Post hoc analysis of SHBG in samples derived from a randomized, open-labeled crossover trial was carried out in 20 T1DM patients: 50% males, mean age 43 (±13 years, diabetes duration 23 (±11 years, and hemoglobin A1c (HbA1c 8.7 (±1.1 (72 (±12 mmol/mol. As secondary outcomes, testosterone, 17-β-estradiol, luteinizing hormone (LH, and follicle-stimulating hormone (FSH were analyzed. Results Estimated mean change in SHBG was −10.3nmol/L (95% CI: −17.4, −3.2 during CIPII and 3.7nmol/L (95% CI: −12.0, 4.6 during SC insulin treatment. Taking the effect of treatment order into account, the difference in SHBG between therapies was −6.6nmol/L (95% CI: −17.5, 4.3; −12.7nmol/L (95% CI: −25.1, −0.4 for males and −1.7nmol/L (95% CI: −24.6, 21.1 for females, respectively. Among males, SHBG and testosterone concentrations changed significantly during CIPII; −15.8nmol/L (95% CI: −24.2, −7.5 and −8.3nmol/L (95% CI: −14.4, −2.2, respectively. The difference between CIPII and SC insulin treatment was also significant for change in FSH 1.2U/L (95% CI: 0.1, 2.2 among males. Conclusions SHBG concentrations decreased significantly during CIPII treatment. Moreover, the difference in change between CIPII and SC insulin therapy was significant for SHBG and FSH among males. These findings support the hypothesis that portal insulin administration influences circulating SHBG and sex steroids.

  11. The effects of trioctyl trimellitate concentration on crosslinking

    International Nuclear Information System (INIS)

    Jamaliah Sharif; Rozana Abu Bakar

    1997-01-01

    The effects of trimellitate type plasticizer concentration on PVC formulation were investigated. The results show that the degree of crosslinking is higher in the PVC compounds containing lower concentration of plasticizer compared to others. The tensile properties were decreased with the increase of plasticizer. However, the ageing properties of the lower concentration samples were very poor. The electrical properties of the compounds were acceptable with the volume resistivity value above 1014 . The heat deformation properties of the samples also improved after irradiation

  12. Characterization of high concentration dust generator

    International Nuclear Information System (INIS)

    Shimura, Toichiro; Yokochi, Akira

    1999-01-01

    This paper describes the development of fluidized bed type high concentration dust generator that keeps for long period dust concentration range of about 10 mg/m 3 for the study of working place monitoring system and evaluation of respirator. The generator is keeping constant powder in fluidized bed for keeping the dust concentration. It is necessary to keep constant feeding rate of powder in order to keep the quantity of dust in the fluidized bed. Our generator enables to obtain constant feeding rate by a screw feeder and by using mixed powder with fluidising particles (glass beads) before feeding. The generator produces high concentration dust of 11.3 mg/m 3 ± 1.0 mg/m 3 for about 5 hours and keeps the dust size 4.2-4.6 μm in mass median aerodynamic diameter with reasonable reproducibility. (author)

  13. Wild-type MIC distributions of four fluoroquinolones active against Mycobacterium tuberculosis in relation to current critical concentrations and available pharmacokinetic and pharmacodynamic data.

    Science.gov (United States)

    Angeby, K A; Jureen, P; Giske, C G; Chryssanthou, E; Sturegård, E; Nordvall, M; Johansson, A G; Werngren, J; Kahlmeter, G; Hoffner, S E; Schön, T

    2010-05-01

    To describe wild-type distributions of the MIC of fluoroquinolones for Mycobacterium tuberculosis in relation to current critical concentrations used for drug susceptibility testing and pharmacokinetic/pharmacodynamic (PK/PD) data. A 96-stick replicator on Middlebrook 7H10 medium was used to define the MICs of ciprofloxacin, ofloxacin, moxifloxacin and levofloxacin for 90 consecutive clinical strains and 24 drug-resistant strains. The MICs were compared with routine BACTEC 460 susceptibility results and with MIC determinations in the BACTEC MGIT 960 system in a subset of strains using ofloxacin as a class representative. PK/PD data for each drug were reviewed in relation to the wild-type MIC distribution. The wild-type MICs of ciprofloxacin, ofloxacin, moxifloxacin and levofloxacin were distributed from 0.125 to 1, 0.25 to 1, 0.032 to 0.5 and 0.125 to 0.5 mg/L, respectively. The MIC data correlated well with the BACTEC 960 MGIT and BACTEC 460 results. PD indices were the most favourable for levofloxacin, followed by moxifloxacin, ofloxacin and ciprofloxacin. We propose S (susceptible) concentrations of S

  14. Megalourethra with Y-Type Duplication of Urethra Presented as Perianal Fistula: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Shashi Verma

    2015-01-01

    Full Text Available Megalourethra with Y-type duplication is an extremely rare anomaly. We report here one such case, diagnosed with retrograde urethrogram, which was done from both penile meatus and perianal opening simultaneously. Patient was successfully treated by laser optical internal urethrotomy (OIU, excision of duplicated urethra, and reduction urethroplasty in a single stage.

  15. Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetes

    DEFF Research Database (Denmark)

    Pfleger, C.; Kaas, A.; Hansen, L.

    2008-01-01

    Th1 related chemokines CCL3 and CCL5 and Th2 related CCL4 as ligands of the receptor CCR5 contribute to disease development in animal models of type 1 diabetes. In humans, no data are available addressing the role of these chemokines regarding disease progression and remission. We investigated...... longitudinally circulating concentrations of CCR5 ligands of 256 newly diagnosed patients with type 1 diabetes. CCR5 ligands were differentially associated with beta-cell function and clinical remission. CCL5 was decreased in remitters and positively associated with HbA1c suggestive of a Th1 associated...... of CCR5 by therapeutic agents such as maraviroc may provide a new therapeutic target to ameliorate disease progression in type 1 diabetes. (C) 2008 Elsevier Inc. All rights reserved Udgivelsesdato: 2008/7...

  16. Creatine Kinase Activity in Patients with Diabetes Mellitus Type I and Type II

    Directory of Open Access Journals (Sweden)

    Adlija Jevrić-Čaušević

    2006-08-01

    Full Text Available Diabetes mellitus can be looked upon as an array of diseases, all of which exhibit common symptoms. While pathogenesis of IDDM (insulin dependant diabetes mellitus is well understood, the same is not true for diabetes mellitus type II. In the latter case, relative contribution of the two factors (insulin resistance or decreased insulin secretion varies individually, being highly increased in peripheral tissues and strictly dependant on insulin for glucose uptake. Moreover, in patients with diabetes mellitus type II, disbalance at the level of regulation of glucose metabolism as well as lipid metabolism has been noted in skeletal muscles. It is normal to assume that in this type of diabetes, these changes are reflected at the level of total activity of enzyme creatine kinase. This experimental work was performed on a group of 80 regular patients of Sarajevo General Hospital. Forty of those patients were classified as patients with diabetes type I and forty as patients with diabetes type II. Each group of patients was carefully chosen and constituted of equal number of males and females. The same was applied for adequate controls. Concentration of glucose was determined for each patient with GOD method, while activity of creatine kinase was determined with CK-NAC activated kit. Statistical analysis of the results was performed with SPSS software for Windows. Obtained results point out highly expressed differences in enzyme activity between two populations examined. Changes in enzyme activity are more expressed in patients with diabetes type II. Positive correlation between concentration of glucose and serum activity of the enzyme is seen in both categories of diabetic patients which is not the case for the patients in control group. At the same time, correlation between age and type of diabetes does exist . This is not followed at the level of enzyme activity or concentration of glucose.

  17. CIS-Type PV Device Fabrication by Novel Techniques; Phase I Annual Technical Report, 1 July 1998 - 30 June 1999

    International Nuclear Information System (INIS)

    Basol, B.M.; Halani, A.; Kapur, V.K.; Leidholm, C.R.; Norsworthy, G.; Roe, R.

    1999-01-01

    This report describes work performed by International Solar Electric Technology, Inc. (ISET) during phase I of the R and D partnership subcontract titled ''CIS-Type PV Device Fabrication by Novel Techniques.'' The objective of this program is to bring ISET's novel non-vacuum CIS technology closer to commercialization by concentrating on issues such as device-efficiency improvement, larger-bandgap absorber growth, and module fabrication. Advances made in CIS and related compound solar cell fabrication processes have clearly shown that these materials and device structures can yield power conversion efficiencies in the 15%-20% range. However, many of the laboratory results on CIS-type devices have been obtained using relatively high-cost vacuum-based deposition techniques. The present project was specifically geared toward developing a low-cost, non-vacuum ''particle deposition'' method for CIS-type absorber growth. There are four major processing steps in this technique: i) preparation of a starting powder containing all or some of the chemical species constituting CIS, ii) preparation of an ink using the starting powder, iii) deposition of the ink on a substrate in the form of a thin precursor layer, and iv) conversion of the precursor layer into a fused photovoltaic absorber through annealing steps. During this Phase I program, ISET worked on tasks that were geared toward the following goals: i) elimination of back-contact problems, ii) growth of large-bandgap absorbers, and iii) fabrication of mini-modules. As a result of the Phase I research, a Mo back-contact structure was developed that eliminated problems that resulted in poor mechanical integrity of the absorber layers. Sulfur inclusion into CIS films through high-temperature sulfurization in H2S gas was also studied. It was determined that S diffusion was a strong function of the stoichiometry of the CIS layer. Sulfur was found to diffuse rapidly through the Cu-rich films, whereas the diffusion constant was

  18. Direct determination of atom and radical concentrations in thermal reactions of hydrocarbons and other gases. Progress report, January 1, 1977--December 31, 1977

    International Nuclear Information System (INIS)

    Skinner, G.B.; Lifshitz, A.; Wood, D.R.; Chiang, C.C.

    1978-01-01

    This is a second annual progress report on this project. The period covered by the first report (June through December, 1976) was devoted to building and testing a shock tube and an optical system to be used to measure H and D atom concentrations. During 1977 this apparatus was completed and used. The performance of our microwave discharge lamps was characterized by numerous high-resolution spectroscopic profiles, so that the shapes of the Lyman-alpha lines produced under various operating conditions are now quite well-known. Measurements of H or D atom concentrations in shock-heated mixtures of D 2 -N 2 O-Ar, D 2 -O 2 -Ar and H 2 -O 2 -Ar have been made. During the balance of the contract year (January 1 through May 31, 1978) measurements of H or D atom concentrations in shock-heated mixtures of CD 4 -Ar, C 8 H 18 (2,2,3,3, tetramethyl butane)-Ar, C 8 H 18 -CH 4 -Ar, C 3 H 8 -Ar and C 3 H 8 -CH 4 -Ar will be made, and kinetic data on reactions of H and D atoms deduced from the experimental results

  19. Dentinogenesis imperfect a type II: A case report with 17 years of follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Gama, Francisco Jose Reis; Correa, Isabella Sousa; Valerio, Claudia Scigliano; Fatima Ferreira, Emanuelle; Manzi, Flavio Ricardo [Pontifical Catholic University of Minas Gerais, Belo Horizonte (Brazil)

    2017-06-15

    Dentinogenesis imperfect a is a dominant autosomal hereditary disorder of dentin formation that affects the deciduous and permanent teeth. Its etiology is characterized by inadequate cell differentiation during odontogenesis. The clinical characteristics of dentinogenesis imperfect a are discolored teeth with a translucency that varies from gray to brown or amber. Radiographically, the teeth exhibit pulp obliteration, thin and short roots, bell-shaped crowns, and periapical bone rarefaction. The aim of this report was to present a case of dentinogenesis imperfect a type II that was followed up over a 17-year period. This report also presents scanning electron microscopy images of the enamel and dentin, showing that both were altered in the affected teeth. The disease characteristics and the treatments that were administered are reported in this study to guide dentists with respect to the need for early diagnosis and adequate follow-up to avoid major sequelae.

  20. Dentinogenesis imperfect a type II: A case report with 17 years of follow-up

    International Nuclear Information System (INIS)

    Gama, Francisco Jose Reis; Correa, Isabella Sousa; Valerio, Claudia Scigliano; Fatima Ferreira, Emanuelle; Manzi, Flavio Ricardo

    2017-01-01

    Dentinogenesis imperfect a is a dominant autosomal hereditary disorder of dentin formation that affects the deciduous and permanent teeth. Its etiology is characterized by inadequate cell differentiation during odontogenesis. The clinical characteristics of dentinogenesis imperfect a are discolored teeth with a translucency that varies from gray to brown or amber. Radiographically, the teeth exhibit pulp obliteration, thin and short roots, bell-shaped crowns, and periapical bone rarefaction. The aim of this report was to present a case of dentinogenesis imperfect a type II that was followed up over a 17-year period. This report also presents scanning electron microscopy images of the enamel and dentin, showing that both were altered in the affected teeth. The disease characteristics and the treatments that were administered are reported in this study to guide dentists with respect to the need for early diagnosis and adequate follow-up to avoid major sequelae

  1. Two in one: report of a patient with spinocerebellar ataxia types 2 and 10.

    Science.gov (United States)

    Kapur, Sachin S; Goldman, Jennifer G

    2012-09-01

    To report a rare case of the coexistence of 2 spinocerebellar ataxia (SCA) mutations in a single patient. Case report. University hospital, Movement Disorders Center. A 54-year-old man of Mexican, American Indian, and French descent with an 11-year history of gait and limb ataxia. Findings of clinical examination, magnetic resonance imaging, and video electroencephalographic monitoring. Neurologic history revealed a gradually progressive gait and limb ataxia along with muscle cramps and sensory symptoms in his distal extremities; examination revealed executive dysfunction, dysarthria, ataxia, and sensory neuronopathy. Episodes of loss of awareness were reported, but electroencephalograms were negative. Brain imaging demonstrated severe cerebellar and brainstem atrophy. Genetic evaluation of the case revealed mutations in both the SCA2 and SCA10 genes. Our patient has a unique combination of genetic mutations for 2 different SCAs, types 2 and 10, which to our knowledge, has not been previously reported. His clinical phenotype is largely consistent with SCA2, but his possible seizures and Mexican heritage suggest influences of SCA10.

  2. Design of a nonimaging Fresnel lens for solar concentrators

    Energy Technology Data Exchange (ETDEWEB)

    Leutz, R.; Akisawa, Atushi; Kashiwagi, Takao [Tokyo University of Agriculture and Technology (Japan). Dept. of Mechanical Systems Engineering; Suzuki, Akio [UNESCO, Paris (France)

    1999-04-01

    An optimum convex shaped nonimaging Fresnel lens is designed following the edge ray principle. The lens is evaluated by tracing rays and calculating a projective optical concentration ratio. This Fresnel lens is intended for use in evacuated tube type solar concentrators, generating mid-temperature heat to drive sorption cycles, or provide industrial process heat. It can also be used along with a secondary concentrator in photovoltaic applications. (author)

  3. Maximum permissible concentrations and negligible concentrations for phthalates (dibutylphthalate and di(2-ethylhexyl)phthlate), with emphasis on endocrine disruptive properties

    NARCIS (Netherlands)

    Wezel AP van; Posthumus R; Vlaardingen P van; Crommentuijn T; Plassche EJ van de; CSR

    This report presents maximal permissible concentrations (MPCs) and negligible concentrations (NCs) are derived for di-n-butylphthalate (DBP) and di(2-ethylhexyl)phthalate (DEHP). Phthalates are often mentioned as suspected endocrine disrupters. Data with endpoints related to the endocrine or

  4. Effects of types of ventilation system on indoor particle concentrations in residential buildings.

    Science.gov (United States)

    Park, J S; Jee, N-Y; Jeong, J-W

    2014-12-01

    The objective of this study was to quantify the influence of ventilation systems on indoor particle concentrations in residential buildings. Fifteen occupied, single-family apartments were selected from three sites. The three sites have three different ventilation systems: unbalanced mechanical ventilation, balanced mechanical ventilation, and natural ventilation. Field measurements were conducted between April and June 2012, when outdoor air temperatures were comfortable. Number concentrations of particles, PM2.5 and CO2 , were continuously measured both outdoors and indoors. In the apartments with natural ventilation, I/O ratios of particle number concentrations ranged from 0.56 to 0.72 for submicron particles, and from 0.25 to 0.60 for particles larger than 1.0 μm. The daily average indoor particle concentration decreased to 50% below the outdoor level for submicron particles and 25% below the outdoor level for fine particles, when the apartments were mechanically ventilated. The two mechanical ventilation systems reduced the I/O ratios by 26% for submicron particles and 65% for fine particles compared with the natural ventilation. These results showed that mechanical ventilation can reduce exposure to outdoor particles in residential buildings. Results of this study confirm that mechanical ventilation with filtration can significantly reduce indoor particle levels compared with natural ventilation. The I/O ratios of particles substantially varied at the naturally ventilated apartments because of the influence of variable window opening conditions and unsteadiness of wind flow on the penetration of outdoor air particles. For better prediction of the exposure to outdoor particles in naturally ventilated residential buildings, it is important to understand the penetration of outdoor particles with variable window opening conditions. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. 210Po and 210Pb concentrations in fish consumed in Syria

    International Nuclear Information System (INIS)

    Al-Masri, M.S.; Mamish, S.; Budeir, Y.; Nashwaty, A

    2001-01-01

    Edible part of 36 types of sea fish collected from local market (Lattakia, Tartus, Banias) and seven types of river fish (Euphrate river and Mzerib lake) have been analyzed for sup 2 sup 1 sup 0 Po and sup 2 sup 1 sup 0 Pb. Results of analysis have shown that sup 2 sup 1 sup 0 Po and sup 2 sup 1 sup 0 Pb concentrations in sea fish varied between 0.27 and 27.48 Bq/kg and between 0.05 and 0.38 Bq/kg, respectively while for river fish concentrations were relatively low and varied between 0.61 and 3.08 Bq/kg for sup 2 sup 1 sup 0 Po and between 0.04 and 0.10 Bq/kg for sup 2 sup 1 sup 0 Pb. In addition, the Syrian adults daily intakes of sup 2 sup 1 sup 0 Po and sup 2 sup 1 sup 0 Pb have been estimated and found to be 6.0 and 0.24 mBq respectively. These intakes are much less than those reported in other areas in the world. The collective dose was also determined and found to be about 5.09 man.Sv for polonium sup 2 sup 1 sup 0 and 2.93 man.Sv for lead sup 2 sup 1 sup 0. (author)

  6. Concentrations in the Local Association. 1. The southern concentrations NGC 2516, IC 2602, Centaurus-Lupus and Upper Scorpius

    Energy Technology Data Exchange (ETDEWEB)

    Eggen, O J [Cerro Tololo Inter-American Observatory, La Serena (Chile)

    1983-07-01

    Extensive intermediate band and H..beta.. observations and the available astrometry, have been used to support the suggestions that (1) several southern concentrations of stars are moving with the Pleiades and ..cap alpha.. Persei clusters (Local Association) and (2) the Local Association contains an appreciable percentage of the main-sequence stars near the Sun but the non-random distribution of the brighter association members focuses attention on a few concentrations, or 'clusters'. (3) All of the concentrations discussed here are larger than about 10 pc and the largest, in Lupus-Centaurus, is shown to be accompanied by A to G type main-sequence stars.

  7. Concentrations and geographic distribution of selected organic pollutants in Scottish surface soils

    International Nuclear Information System (INIS)

    Rhind, S.M.; Kyle, C.E.; Kerr, C.; Osprey, M.; Zhang, Z.L.; Duff, E.I.; Lilly, A.; Nolan, A.; Hudson, G.; Towers, W.; Bell, J.; Coull, M.; McKenzie, C.

    2013-01-01

    Concentrations of selected persistent organic pollutants (POPs) representing three chemical classes (polycyclic aromatic hydrocarbons (PAH), polybrominated diphenyl ethers (PBDE) and polychlorinated biphenyls (PCB) and the organic pollutant diethylhexyl phthalate (DEHP), were determined in surface soil samples (0–5 cm) collected at 20 km grid intersects throughout Scotland over a three-year period. Detectable amounts of all chemical classes and most individual congeners were present in all samples. There were no consistent effects of soil or vegetation type, soil carbon content, pH, altitude or distance from centres of population on concentrations which exhibited extreme variation, even in adjacent samples. It is concluded that soil POPs and DEHP concentrations and associated rates of animal and human exposure were highly variable, influenced by multiple, interacting factors, and not clearly related to local sources but possibly related to wet atmospheric deposition and the organic carbon content of the soil. -- Highlights: •Concentrations of selected organic pollutants in Scottish soils were determined. •Concentrations were highly variable. •There were few effects of soil or vegetation type, soil carbon, pH or altitude. •Distance from cities was not an important determinant of concentrations. •Atmospheric deposition and soil organic carbon content may affect concentrations. -- Soil concentrations of anthropogenic persistent organic pollutants are not clearly related to soil type or pH, vegetation, altitude, or distance from pollutant sources

  8. Luminescence dynamics in type-II GaAs/AlAs superlattices near the type-I to type-II crossover

    DEFF Research Database (Denmark)

    Langbein, Wolfgang Werner; Kalt, H.; Hvam, Jørn Märcher

    1996-01-01

    We report on a study of the time-resolved luminescence of type-II GaAs/AlAs superlattices near the type-I to type-II crossover. In spite of the slight type-II band alignment, the luminescence is dominated by the type-I transition. This is due to the inhomogeneous broadening of the type-I transiti...

  9. Deficiency of Carbonic Anhydrase II Results in a Urinary Concentrating Defect

    Directory of Open Access Journals (Sweden)

    Devishree Krishnan

    2018-01-01

    Full Text Available Carbonic anhydrase II (CAII is expressed along the nephron where it interacts with a number of transport proteins augmenting their activity. Aquaporin-1 (AQP1 interacts with CAII to increase water flux through the water channel. Both CAII and aquaporin-1 are expressed in the thin descending limb (TDL; however, the physiological role of a CAII-AQP1 interaction in this nephron segment is not known. To determine if CAII was required for urinary concentration, we studied water handling in CAII-deficient mice. CAII-deficient mice demonstrate polyuria and polydipsia as well as an alkaline urine and bicarbonaturia, consistent with a type III renal tubular acidosis. Natriuresis and hypercalciuria cause polyuria, however, CAII-deficient mice did not have increased urinary sodium nor calcium excretion. Further examination revealed dilute urine in the CAII-deficient mice. Urinary concentration remained reduced in CAII-deficient mice relative to wild-type animals even after water deprivation. The renal expression and localization by light microscopy of NKCC2 and aquaporin-2 was not altered. However, CAII-deficient mice had increased renal AQP1 expression. CAII associates with and increases water flux through aquaporin-1. Water flux through aquaporin-1 in the TDL of the loop of Henle is essential to the concentration of urine, as this is required to generate a concentrated medullary interstitium. We therefore measured cortical and medullary interstitial concentration in wild-type and CAII-deficient mice. Mice lacking CAII had equivalent cortical interstitial osmolarity to wild-type mice: however, they had reduced medullary interstitial osmolarity. We propose therefore that reduced water flux through aquaporin-1 in the TDL in the absence of CAII prevents the generation of a maximally concentrated medullary interstitium. This, in turn, limits urinary concentration in CAII deficient mice.

  10. MRI findings of type II sacral agenesis: A case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang A; Kim, Myung Soon; Kwon, Woo Cheol [Dept. of Radiology, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju (Korea, Republic of)

    2016-07-15

    Sacral agenesis (or caudal regression syndrome) is a rare congenital anomaly involving various levels of coccygeal, sacral, and even lumbar or lower thoracic vertebral dysgenesis, as well as spinal cord abnormalities. A few cases have been previously reported in Korea, especially based upon MRI findings. We describe a case of a 4-year-old girl with partially bilateral agenesis of the sacrum (type II), and club-shaped (chisel-shaped) spinal cord disruption. We also review MRI findings of sacral agenesis, focused on classification and radiological findings.

  11. Frequency and risk factors of severe hypoglycaemia in insulin-treated Type 2 diabetes

    DEFF Research Database (Denmark)

    Akram, K; Pedersen-Bjergaard, U; Carstensen, B

    2006-01-01

    AIMS: The reported risk of severe hypoglycaemia in insulin-treated Type 2 diabetes is highly variable and few studies have evaluated the influence of risk factors. We assessed the incidence and the influence of potential risk factors for severe hypoglycaemia in a questionnaire survey in subjects...... with insulin-treated Type 2 diabetes receiving currently recommended multifactorial intervention. METHODS: Consecutive patients with insulin-treated Type 2 diabetes (n = 401) completed a questionnaire about occurrence of hypoglycaemia in the past, hypoglycaemia awareness and socio-demographic factors. A zero...... treatment and treatment with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor antagonists (ARBs) were associated with reduced risk. C-peptide concentration and HbA1c were not associated with the risk of severe hypoglycaemia. CONCLUSIONS: In this cohort of insulin-treated Type 2...

  12. Methods to homogenize electrochemical concentration cell (ECC ozonesonde measurements across changes in sensing solution concentration or ozonesonde manufacturer

    Directory of Open Access Journals (Sweden)

    T. Deshler

    2017-06-01

    Full Text Available Ozone plays a significant role in the chemical and radiative state of the atmosphere. For this reason there are many instruments used to measure ozone from the ground, from space, and from balloons. Balloon-borne electrochemical cell ozonesondes provide some of the best measurements of the ozone profile up to the mid-stratosphere, providing high vertical resolution, high precision, and a wide geographic distribution. From the mid-1990s to the late 2000s the consistency of long-term records from balloon-borne ozonesondes has been compromised by differences in manufacturers, Science Pump (SP and ENSCI (EN, and differences in recommended sensor solution concentrations, 1.0 % potassium iodide (KI and the one-half dilution: 0.5 %. To investigate these differences, a number of organizations have independently undertaken comparisons of the various ozonesonde types and solution concentrations, resulting in 197 ozonesonde comparison profiles. The goal of this study is to derive transfer functions to allow measurements outside of standard recommendations, for sensor composition and ozonesonde type, to be converted to a standard measurement and thus homogenize the data to the expected accuracy of 5 % (10 % in the stratosphere (troposphere. Subsets of these data have been analyzed previously and intermediate transfer functions derived. Here all the comparison data are analyzed to compare (1 differences in sensor solution composition for a single ozonesonde type, (2 differences in ozonesonde type for a single sensor solution composition, and (3 the World Meteorological Organization's (WMO and manufacturers' recommendations of 1.0 % KI solution for Science Pump and 0.5 % KI for ENSCI. From the recommendations it is clear that ENSCI ozonesondes and 1.0 % KI solution result in higher amounts of ozone sensed. The results indicate that differences in solution composition and in ozonesonde type display little pressure dependence at pressures

  13. Sandstone-type uranium deposits

    International Nuclear Information System (INIS)

    Finch, W.I.; Davis, J.F.

    1985-01-01

    World-class sandstone-type uranium deposits are defined as epigenetic concentrations of uranium minerals occurring as uneven impregnations and minor massive replacements primarily in fluvial, lacustrine, and deltaic sandstone formations. The main purpose of this introductory paper is to define, classify, and introduce to the general geologic setting for sandstone-type uranium deposits

  14. Does an elevated CO2 concentration decrease dark respiration in trees? Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Long, Stephen [Univ. of Illinois, Urbana-Champaign, IL (United States)

    2003-12-31

    Averaged across many previous investigations, doubling the CO2 concentration ([CO2]) has frequently been reported to cause an instantaneous reduction of leaf dark respiration measured as CO2 efflux. No known mechanism accounts for this effect. While four recent studies have shown that the measurement of respiratory CO2 efflux is prone to experimental artifacts that could account for the reported response, papers published since the start of the current research continue to report an instantaneous depression of respiratory CO2 efflux by elevation of [CO2]. Here, these artifacts are avoided by use of a high-resolution dual channel oxygen analyzer within an open gas exchange system to measure respiratory 02 uptake in normal air. Leaf 02 uptake was determined in response to instantaneous elevation of [CO2] in nine contrasting species and to long-term elevation in seven species from four of the DOE-sponsored long-term elevated [CO2] field experiments. Over one thousand separate measurements of respiration failed to reveal any decrease in respiratory 02 uptake with an instantaneous increase in [CO2]. Respiration was found insensitive not only to doubling [CO2], but also to a five-fold increase and to decrease to zero.

  15. FY 1999 Report on research results. Research and development of high-temperature air combustion technology (Attachments); 1999 nendo koon kuki nensho seigyo gijutsu kenkyu kaihatsu seika hokokusho. Shiryoshu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This project surveys the actual conditions of dioxins emissions discharged from the waste incinerators in commercial service, in order to establish the database for evaluating the effects when the (high-temperature air combustion technology) is applied to waste incinerators. The survey covers 1018 totally continuous incinerators and 724 quasi-continuous incinerators in service in Japan, and the data are analyzed by incinerator types and items for correlating each element with one another, based on The Waste Incinerator Register issued by The Wastes Research Foundation and Dioxins Concentrations in Flue Gases from General Waste Incinerators issued by Health and Welfare Ministry. For 1105 mechanized batch type combustion furnaces and 159 stationary batch type combustion furnaces, only discharged dioxins concentrations are analyzed by incineration capacity. The attachments include (1) report on the survey results of the actual conditions of dioxins emissions, (2) report on the survey results of the actual conditions of dioxins concentrations in flue gases discharged from general waste incinerators, (3) report on the survey results of the actual conditions of NO emissions discharged from sewer sludge incinerators, and (4) and (5) report on the survey results of the actual conditions of NO emissions discharged from fluidized bed type general waste incinerators. (NEDO)

  16. Use of a thin-film evaporator for bitumen coating of radioactive concentrates

    International Nuclear Information System (INIS)

    Lefillatre, G.; Rodier, J.; Hullo, R.; Cudel, Y.; Rodi, L.

    1969-01-01

    Following the development in the laboratory of a process for coating evaporation concentrates with bitumen, a technological study of this coating process has been undertaken. The report describes a pilot installation for the bitumen coating of concentrates, which uses a thin-film evaporator LUWA L 150. The first, inactive series of tests was designed to determine the maximum and optimum capacities of the evaporator by varying the amounts of bitumen and of concentrate, the rotor speed and the thermo-fluid temperature. Two rotors were tested, one of conventional type, the other a model especially designed for high viscosity products. The maximum capacity of evaporation of the apparatus is 72 kg/hr for a heating temperature of 221 deg. C. During normal operation, the evaporator can produce 50 kg/hr of coated product containing 55 to 60 per cent of bitumen (Mexphalte 40/50), the water content of the product remaining under 0.5 per cent. A second series of tests will shortly be carried out on this pilot installation using, in particular, bituminous emulsions containing mainly Mexphalte 40/50 and 80/100. (authors) [fr

  17. Safety analysis report for packaging (onsite) for limited type Bmaterial in the CNS 14-215H cask

    International Nuclear Information System (INIS)

    Flanagan, B.D.

    1997-01-01

    The purpose of this Safety Analysis Report for Packaging is to provide the analyses and evaluations necessary to demonstrate that the CNS 14-215H cask provided by Chem-Nuclear Systems Inc. can safety transport greater than Type A quantities of radioactive material on the Hanford Site. The CNS 14-215H cask was chosen for its loading abilities, availability, and because it has a Certificate of Compliance (CoC) issued by the U.S. Nuclear Regulatory Commission (NRC) for transporting low specific activity in quantities greater than Type A material in commerce. Although the CDC does not cover greater than Type A material not meeting LSA requirements, it does allow for an established level of protection in determining the safety of transporting Type B material on the Hanford Site

  18. Low-Concentration Tributyltin Decreases GluR2 Expression via Nuclear Respiratory Factor-1 Inhibition.

    Science.gov (United States)

    Ishida, Keishi; Aoki, Kaori; Takishita, Tomoko; Miyara, Masatsugu; Sakamoto, Shuichiro; Sanoh, Seigo; Kimura, Tomoki; Kanda, Yasunari; Ohta, Shigeru; Kotake, Yaichiro

    2017-08-11

    Tributyltin (TBT), which has been widely used as an antifouling agent in paints, is a common environmental pollutant. Although the toxicity of high-dose TBT has been extensively reported, the effects of low concentrations of TBT are relatively less well studied. We have previously reported that low-concentration TBT decreases α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptor subunit 2 ( GluR2 ) expression in cortical neurons and enhances neuronal vulnerability to glutamate. However, the mechanism of this TBT-induced GluR2 decrease remains unknown. Therefore, we examined the effects of TBT on the activity of transcription factors that control GluR2 expression. Exposure of primary cortical neurons to 20 nM TBT for 3 h to 9 days resulted in a decrease in GluR2 mRNA expression. Moreover, TBT inhibited the DNA binding activity of nuclear respiratory factor-1 (NRF-1), a transcription factor that positively regulates the GluR2 . This result indicates that TBT inhibits the activity of NRF-1 and subsequently decreases GluR2 expression. In addition, 20 nM TBT decreased the expression of genes such as cytochrome c, cytochrome c oxidase (COX) 4, and COX 6c, which are downstream of NRF-1. Our results suggest that NRF-1 inhibition is an important molecular action of the neurotoxicity induced by low-concentration TBT.

  19. Low-Concentration Tributyltin Decreases GluR2 Expression via Nuclear Respiratory Factor-1 Inhibition

    Science.gov (United States)

    Ishida, Keishi; Aoki, Kaori; Takishita, Tomoko; Miyara, Masatsugu; Sakamoto, Shuichiro; Sanoh, Seigo; Kimura, Tomoki; Kanda, Yasunari; Ohta, Shigeru; Kotake, Yaichiro

    2017-01-01

    Tributyltin (TBT), which has been widely used as an antifouling agent in paints, is a common environmental pollutant. Although the toxicity of high-dose TBT has been extensively reported, the effects of low concentrations of TBT are relatively less well studied. We have previously reported that low-concentration TBT decreases α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptor subunit 2 (GluR2) expression in cortical neurons and enhances neuronal vulnerability to glutamate. However, the mechanism of this TBT-induced GluR2 decrease remains unknown. Therefore, we examined the effects of TBT on the activity of transcription factors that control GluR2 expression. Exposure of primary cortical neurons to 20 nM TBT for 3 h to 9 days resulted in a decrease in GluR2 mRNA expression. Moreover, TBT inhibited the DNA binding activity of nuclear respiratory factor-1 (NRF-1), a transcription factor that positively regulates the GluR2. This result indicates that TBT inhibits the activity of NRF-1 and subsequently decreases GluR2 expression. In addition, 20 nM TBT decreased the expression of genes such as cytochrome c, cytochrome c oxidase (COX) 4, and COX 6c, which are downstream of NRF-1. Our results suggest that NRF-1 inhibition is an important molecular action of the neurotoxicity induced by low-concentration TBT. PMID:28800112

  20. PROJECT EXPERIENCE REPORT DEMOLITION OF HANFORDS 233-S PLUTONIUM CONCENTRATION FACILITY

    International Nuclear Information System (INIS)

    BERLIN, G.T.; ORGILL, T.K.

    2004-01-01

    This report provides a summary of the preparation, operations, innovative work practices, and lessons learned associated with demolition of the 2334 Plutonium Concentration Facility. This project represented the first open-air demolition of a highly-contaminated plutonium facility at the Hanford Site. This project may also represent the first plutonium facility in the US. Department of Energy (DOE) complex to have been demolished without first decontaminating surfaces to near ''free release'' standards. Demolition of plutonium contaminated structures, if not properly managed, can subject cleanup personnel and the environment to significant risk. However, with proper sequencing and innovative use of commercially available equipment, materials, and services, this project demonstrated that a plutonium processing facility can be demolished while avoiding the need to perform extensive decontamination or to construct large enclosures. This project utilized an excavator with concrete shears, diamond circular saws, water misting and fogging equipment, commercially available fixatives and dust suppressants, conventional mobile crane and rigging services, and near real-time modeling of meteorological and radiological conditions. Following a significant amount of preparation, actual demolition of the 233-S Facility began in October 2003 and was completed in late April 2004. The knowledge and experience gained on this project are important to the Hanford Site as additional plutonium processing facilities are scheduled for demolition in the near future. Other sites throughout the DOE Complex may also be faced with similar challenges. Numerous innovations and effective work practices were implemented on this project. Accordingly, a series of ''Lessons Learned and Innovative Practices Fact Sheets'' were developed and are included as an appendix to this report. This collection of fact sheets is not intended to capture every innovative work practice and lesson learned, but rather