WorldWideScience

Sample records for reported compromised integrity

  1. Compromised genomic integrity impedes muscle growth after Atrx inactivation.

    Science.gov (United States)

    Huh, Michael S; Price O'Dea, Tina; Ouazia, Dahmane; McKay, Bruce C; Parise, Gianni; Parks, Robin J; Rudnicki, Michael A; Picketts, David J

    2012-12-01

    ATR-X syndrome is a severe intellectual disability disorder caused by mutations in the ATRX gene. Many ancillary clinical features are attributed to CNS deficiencies, yet most patients have muscle hypotonia, delayed ambulation, or kyphosis, pointing to an underlying skeletal muscle defect. Here, we identified a cell-intrinsic requirement for Atrx in postnatal muscle growth and regeneration in mice. Mice with skeletal muscle-specific Atrx conditional knockout (Atrx cKO mice) were viable, but by 3 weeks of age presented hallmarks of underdeveloped musculature, including kyphosis, 20% reduction in body mass, and 34% reduction in muscle fiber caliber. Atrx cKO mice also demonstrated a marked regeneration deficit that was not due to fewer resident satellite cells or their inability to terminally differentiate. However, activation of Atrx-null satellite cells from isolated muscle fibers resulted in a 9-fold reduction in myoblast expansion, caused by delayed progression through mid to late S phase. While in S phase, Atrx colocalized specifically to late-replicating chromatin, and its loss resulted in rampant signs of genomic instability. These observations support a model in which Atrx maintains chromatin integrity during the rapid developmental growth of a tissue.

  2. Surgeon-Reported Needs for Improved Training in Identifying and Managing Free Flap Compromise.

    Science.gov (United States)

    McMillan, Catherine; D'Hondt, Veerle; Marshall, Alexandra H; Binhammer, Paul; Lipa, Joan; Snell, Laura

    2017-07-01

    Background This study examined the need for improved training in the identification and management of free flap (FF) compromise and assessed a potential role for simulated scenario training. Methods Online needs assessment surveys were completed by plastic surgeons and a subsample with expertise in microsurgery education participated in focus groups. Data were analyzed using descriptive statistics and mixed qualitative methods. Results In this study, 77 surgeons completed surveys and 11 experts participated in one of two focus groups. Forty-nine (64%) participants were educators, 65 and 45% of which reported having an insufficient volume of FF cases to adequately teach the management and identification of compromise, respectively. Forty-three percent of educators felt that graduating residents are not adequately prepared to manage FF compromise independently. Exposure to normal and abnormal FF cases was felt to be critical for effective training by focus group participants. Experts identified low failure rates, communication issues, and challenging teaching conditions as current barriers to training. Most educators (74%) felt that simulated scenario training would be "very useful" or "extremely useful" to current residents. Focus groups highlighted the need for a widely accepted algorithm for re-exploration and salvage on which to base the development of a training adjunct consisting of simulated scenarios. Conclusion Trainee exposure to FF compromise is inadequate in existing plastic surgery programs. Early exposure, high case volume, and a standardized algorithmic approach to management with a focus on decision making may improve training. Simulated scenario training may be valuable in addressing current barriers. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  3. Immediate Implant Loading in Compromised Maxillary Partially Edentulous Arch- A Case Report

    Science.gov (United States)

    Ramesh, Sachhi; Patil, Veena; Jain, Anoop; Gaddale, Reetika

    2014-01-01

    As the aesthetic demands are increasing day by day, demand of immediate restoration or replacement of teeth is also increasing. Because of this, immediate implant placement, along with immediate loading of implant, is a favourite treatment option for patients as well as dentists. This case report discusses the immediate implant loading in compromised maxillary anterior region, in which patient got immediate restoration of edentulous area. More importantly, from the patients’ points of view, immediate loading can produce positive social and psychological effects. PMID:24959519

  4. Fibre reinforcement in a structurally compromised endodontically treated molar: a case report

    Science.gov (United States)

    de Ataide, Ida de Noronha; Fernandes, Marina; Lambor, Rajan

    2016-01-01

    The reconstruction of structurally compromised posterior teeth is a rather challenging procedure. The tendency of endodontically treated teeth (ETT) to fracture is considerably higher than vital teeth. Although posts and core build-ups followed by conventional crowns have been generally employed for the purpose of reconstruction, this procedure entails sacrificing a considerable amount of residual sound enamel and dentin. This has drawn the attention of researchers to fibre reinforcement. Fibre-reinforced composite (FRC), designed to replace dentin, enables the biomimetic restoration of teeth. Besides improving the strength of the restoration, the incorporation of glass fibres into composite resins leads to favorable fracture patterns because the fibre layer acts as a stress breaker and stops crack propagation. The following case report presents a technique for reinforcing a badly broken-down ETT with biomimetic materials and FRC. The proper utilization of FRC in structurally compromised teeth can be considered to be an economical and practical measure that may obviate the use of extensive prosthetic treatment. PMID:27200283

  5. Voting rights for psychiatric patients: compromise of the integrity of elections, or empowerment and integration into the community?

    Science.gov (United States)

    Doron, Adiel; Kurs, Rena; Stolovy, Tali; Secker-Einbinder, Aya; Raba, Alla

    2014-01-01

    Participation of the mentally-ill in elections promotes integration into the community. In many countries, individuals with compromised mental incompetence who have legal guardians are denied the right to vote. In Israel, mental health consumers are eligible to vote. We evaluated the capacity of psychiatric inpatients with and without legal guardians to understand the nature and effect of voting. Fifty-six inpatients with/without legal guardians were recruited to the study. Participants completed the Competency AssessmentTool for Voting (CAT-V), Brief Psychiatric Rating Scale and the Mini-Mental State Exam. Cluster analysis determined voting capacity using CAT-V as a continuous variable. Subjects who scored >1.6 on the CAT-V (59%) had high capacity to vote. Subjects without guardians revealed significantly higher capacity to vote. Voting capacity positively correlated with cognitive state and negatively correlated with severity of illness. Among patients with legal guardians those who scored >1.6 on the CAT-V maintained the capacity to vote. The right to vote is an important basic right for individuals coping with mental disorders.However, it is important to evaluate the capacity to understand the voting process among individuals with mental disorders who have legal guardians. Thus, the integrity of the elections would be preserved by eliminating the risk of undue influence or manipulation of individuals who lack the capacity to understand the nature and meaning of voting, while preserving the right to vote for those with the capacity to do so, whether or not they have guardians.

  6. Reporter-based screen for Arabidopsis mutants com-promised in nonhost resistance

    Institute of Scientific and Technical Information of China (English)

    CHEN HuaMin; PAN JunSong; ZHAO XiuXiang; ZHOU JianMin; CAI Run

    2008-01-01

    Plants are exposed to many potentially pathogenic microbes in the environment, but each species is only susceptible to a limited number of pathogens. The broad resistance is referred to as nonhost re-sistance. To date, little is known about the underlying mechanism of nonhost resistance and the sig-naling transduction process. Here we describe a simple method for isolating Arabidopsis nonhost re-sistance mutants against a nonadapted bacterial pathogen. A RAP2.6 promoter-driven LUC reporter system was developed to replace the tedious bacterial growth assay during the primary screening. The RAP2.6-LUC reporter gone is normally induced by the virulent bacterium Pseudomonas syringae pv tomato but not the nonadapted bacterium P. syringae pv phaseolicola. By using this method we iso-lated 4 mutants displaying strong reporter activity in response to P. syringae pv phaseolicola, which were characterized in some details, ebsl, ebs2, ebs3, and ebs4 (enhanced bacterial susceptibility) were compromised in resistance against P. syringae pv phaseolicola and/or P. syringae pv tomato. In addi-tion, ebs4 showed enhanced hypersensitive response to the incompatible bacterium P. syringae pv tomato (avrB). These results demonstrated that the method is suited for large scale screening for nonhost resistance mutants.

  7. Integrated Reporting Information System -

    Data.gov (United States)

    Department of Transportation — The Integrated Reporting Information System (IRIS) is a flexible and scalable web-based system that supports post operational analysis and evaluation of the National...

  8. Tick-borne encephalitis virus infects human brain microvascular endothelial cells without compromising blood-brain barrier integrity.

    Science.gov (United States)

    Palus, Martin; Vancova, Marie; Sirmarova, Jana; Elsterova, Jana; Perner, Jan; Ruzek, Daniel

    2017-07-01

    Alteration of the blood-brain barrier (BBB) is a hallmark of tick-borne encephalitis (TBE), a life-threating human viral neuroinfection. However, the mechanism of BBB breakdown during TBE, as well as TBE virus (TBEV) entry into the brain is unclear. Here, primary human microvascular endothelial cells (HBMECs) were infected with TBEV to study interactions with the BBB. Although the number of infected cells was relatively low in culture (10(6)pfu/ml). Infection did not induce any significant changes in the expression of key tight junction proteins or upregulate the expression of cell adhesion molecules, and did not alter the highly organized intercellular junctions between HBMECs. In an in vitro BBB model, the virus crossed the BBB via a transcellular pathway without compromising the integrity of the cell monolayer. The results indicate that HBMECs may support TBEV entry into the brain without altering BBB integrity. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Enhancing water and fertilizer saving without compromising rice yield through integrated crop management

    NARCIS (Netherlands)

    Wardana, I.P.; Gani, A.; Abdulrachmann, S.; Bindraban, P.S.; Keulen, van H.

    2010-01-01

    Water and fertilizer scarcity amid the increasing need of rice production challenges today’s agriculture. Integrated crop management (ICM) is a combination of water, crop, and nutrient management that optimizes the synergistic interaction of these components aiming at improving resource use efficien

  10. Enhancing water and fertilizer saving without compromising rice yield through integrated crop management

    NARCIS (Netherlands)

    Wardana, I.P.; Gani, A.; Abdulrachmann, S.; Bindraban, P.S.; Keulen, van H.

    2010-01-01

    Water and fertilizer scarcity amid the increasing need of rice production challenges today’s agriculture. Integrated crop management (ICM) is a combination of water, crop, and nutrient management that optimizes the synergistic interaction of these components aiming at improving resource use

  11. Integrated Reporting og Integrated Thinking

    DEFF Research Database (Denmark)

    Pontoppidan, Caroline Aggestam; Sonnerfeldt, Amanda

    2017-01-01

    I løbet af de sidste to måneder af 2016, havde vi mulighed for at deltage i to konferencer, med fokus på at udvikle og fremme ‘Integrated Reporting’ (IR) og ‘Integrated Thinking’. Denne artikel søger at videregive nogle af de interessante emner og spørgsmål, der blev drøftet ved disse to begivenh......I løbet af de sidste to måneder af 2016, havde vi mulighed for at deltage i to konferencer, med fokus på at udvikle og fremme ‘Integrated Reporting’ (IR) og ‘Integrated Thinking’. Denne artikel søger at videregive nogle af de interessante emner og spørgsmål, der blev drøftet ved disse...

  12. Decreased Polysaccharide Feruloylation Compromises Plant Cell Wall Integrity and Increases Susceptibility to Necrotrophic Fungal Pathogens

    Directory of Open Access Journals (Sweden)

    Nathan T Reem

    2016-05-01

    Full Text Available The complexity of cell wall composition and structure determines the strength, flexibility, and function of the primary cell wall in plants. However, the contribution of the various components to cell wall integrity and function remains unclear. Modifications of cell wall composition can induce plant responses known as Cell Wall Integrity control. In this study, we used transgenic expression of the fungal feruloyl esterase AnFAE to examine the effect of post-synthetic modification of Arabidopsis and Brachypodium cell walls. Transgenic Arabidopsis plants expressing AnFAE showed a significant reduction of monomeric ferulic acid, increased amounts of wall-associated extensins, and increased susceptibility to Botrytis cinerea, compared with wild type. Transgenic Brachypodium showed reductions in monomeric and dimeric ferulic acids and increased susceptibility to Bipolaris sorokiniana. Upon infection, transgenic Arabidopsis and Brachypodium plants also showed increased expression of several defense-related genes compared with wild type. These results demonstrate a role, in both monocot and dicot plants, of polysaccharide feruloylation in plant cell wall integrity, which contributes to plant resistance to necrotrophic pathogens.

  13. Indirect porcelain veneers in periodontally compromised teeth. The hybrid technique: a case report.

    Science.gov (United States)

    Garcia-Baeza, David; Saavedra, Carlos; Garcia-Adámez, Ramón

    2015-01-01

    The loss of periodontal structure causes an esthetic problem for many patients, especially when the esthetic zone is compromised. Among the various types of solutions is the use of composite resins. While this procedure is not aggressive towards tooth structure, it does require the clinician to have a precise technique, and demands strict longterm maintenance. 1 Another way of treating the compromised teeth is with porcelain veneers. This procedure is especially difficult, however, if carried out on periodontal teeth, as it requires preparation along the roots. 2 The intention of the hybrid technique described in this article is to combine both of these procedures in order to obtain a less aggressive treatment with precise management of the soft tissue and an adequate esthetic outcome. The hybrid technique consists of enlarging the root portion of the teeth with composite resin to obtain a less aggressive tooth preparation, and thereafter placing porcelain veneers.

  14. Functional MRI reveals compromised neural integrity of the face processing network in congenital prosopagnosia.

    Science.gov (United States)

    Avidan, Galia; Behrmann, Marlene

    2009-07-14

    The summed activity of multiple nodes of a distributed cortical network supports face recognition in humans, including "core" ventral occipitotemporal cortex (VOTC) regions, and "extended" regions outside VOTC. Many individuals with congenital prosopagnosia-an impairment in face processing-exhibit normal blood oxygenation level-dependent (BOLD) activation in the core VOTC regions. These individuals evince a reduction in the structural integrity of the white matter tracts connecting VOTC to anterior temporal and frontal cortices, part of the "extended" face network. The impairment in congenital prosopagnosia may arise, therefore, not from a dysfunction of the core VOTC areas but from a failure to propagate signals between the intact VOTC and the extended nodes of the network. Using the fMR adaptation paradigm with famous and unknown faces, we show that individuals with congenital prosopagnosia evince normal adaptation effects in VOTC, indicating sensitivity to facial identity, but show no differential activation for familiar versus unknown faces outside VOTC, particularly in the precuneus/posterior cingulate cortex and the anterior paracingulate cortex. Normal BOLD activation in VOTC is thus insufficient to subserve intact face recognition, and disrupted information propagation between VOTC and the extended face processing network may explain the functional impairment in congenital prosopagnosia.

  15. Decreased Polysaccharide Feruloylation Compromises Plant Cell Wall Integrity and Increases Susceptibility to Necrotrophic Fungal Pathogens.

    Science.gov (United States)

    Reem, Nathan T; Pogorelko, Gennady; Lionetti, Vincenzo; Chambers, Lauran; Held, Michael A; Bellincampi, Daniela; Zabotina, Olga A

    2016-01-01

    The complexity of cell wall composition and structure determines the strength, flexibility, and function of the primary cell wall in plants. However, the contribution of the various components to cell wall integrity (CWI) and function remains unclear. Modifications of cell wall composition can induce plant responses known as CWI control. In this study, we used transgenic expression of the fungal feruloyl esterase AnFAE to examine the effect of post-synthetic modification of Arabidopsis and Brachypodium cell walls. Transgenic Arabidopsis plants expressing AnFAE showed a significant reduction of monomeric ferulic acid, decreased amounts of wall-associated extensins, and increased susceptibility to Botrytis cinerea, compared with wild type. Transgenic Brachypodium showed reductions in monomeric and dimeric ferulic acids and increased susceptibility to Bipolaris sorokiniana. Upon infection, transgenic Arabidopsis and Brachypodium plants also showed increased expression of several defense-related genes compared with wild type. These results demonstrate a role, in both monocot and dicot plants, of polysaccharide feruloylation in plant CWI, which contributes to plant resistance to necrotrophic pathogens.

  16. Wind Integration into Energy Systems with a High Share of Nuclear Power—What Are the Compromises?

    Directory of Open Access Journals (Sweden)

    Behnam Zakeri

    2015-03-01

    Full Text Available Towards low-carbon energy systems, there are countries with ongoing plans for expanding their nuclear power capacity, and simultaneously advancing the role of variable renewable energy sources (RES, namely wind and solar energy. This crossroads of capital-intensive, baseload power production and uncontrollable, intermittent RES may entail new challenges in the optimal and economic operation of power systems. This study examines this case by hourly analysis of a national-level energy system with the EnergyPLAN modeling tool, coupled with wind integration simulations (including uncertainty implemented using MATLAB. We evaluate the maximum feasible wind integration under different scenarios for nuclear power plants, energy demand, and the flexibility of energy infrastructure for a real case study (Finland. We propose wind-nuclear compromise charts to envision the impact of any mix of these two technologies on four parameters: total costs, power exchange, carbon emissions, and renewable energy integration. The results suggest that nuclear power constrains the room for maximum uptake of wind energy by a descending parabolic relationship. If nuclear power production exceeds 50% of the total power demand, wind will be unlikely to penetrate in shares over 15% of the respective demand. Moreover, we investigate the role of four flexibility options: demand side management, electrical energy storage, smart electric heating, and large-scale heat pumps (backed with thermal energy storage. Heat pumps (which are in connection with combined heat and power (CHP and district heating systems offer the highest efficiency in balancing excess power from variable RES. However, power-to-heat options offer a limited capability for absorbing excess power, as oversupply arises mainly in the periods with relatively low demand for heat. This calls for longer-term energy storage and/or other flexibility options to achieve the planned targets in wind-nuclear scenarios.

  17. Self-inflicted Cardiac Injury with Nail Gun Without Hemodynamic Compromise: A Case Report

    Science.gov (United States)

    Ho, Simon; Feranec, Nicholas

    2017-01-01

    Pneumatically powered nail guns have been used in construction since 1959. Penetrating injuries to the heart with nail guns have a wide range of presentations from asymptomatic to cardiac tamponade and exsanguination. Mortality related to cardiac nail gun injuries is similar to knife injuries, estimated at 25%. Surgical exploration is the treatment of choice. We describe a case of self-inflicted nail gun injury to the chest without hemodynamic compromise in a 51-year-old man. Computed tomography (CT) imaging confirmed nail penetrating the right ventricle, with the tip adjacent to but not violating the abdominal aorta. The patient was successfully treated with thoracotomy and foreign body removal. PMID:28191375

  18. Strained Compromises?

    DEFF Research Database (Denmark)

    Ibsen, Christian Lyhne

    The Danish version of flexicurity is not only about a balance between labour market flexibility and social security. Arguably, it is also series of more or less stable underlying compromises between social partners about the main mechanisms and aims of labour market regulation which – supposedly...... – should be focused on employment rather than jobs and competition on quality rather than on labour costs. However, most studies on Danish flexicurity have been carried out under favourable economic conditions with social partners almost naturally agreeing to the merits of the model – at least in principle...... underlines the dangers of building models based on short periods of stability....

  19. Integrated reporting and board features

    OpenAIRE

    Rares HURGHIS

    2017-01-01

    In the last two decades the concept of sustainability reporting gained more importance in the companies’ annual reports, a trend which is embedded also in integrated reporting. Issuing an integrated report became a necessity, because the report explains to the investors how the organization creates value over time. The governance structure, more exactly the board of directors, decides whether or not the company will issue an integrated report. Thus, are there certain features of the board tha...

  20. Integrated system checkout report

    Energy Technology Data Exchange (ETDEWEB)

    1991-08-14

    The planning and preparation phase of the Integrated Systems Checkout Program (ISCP) was conducted from October 1989 to July 1991. A copy of the ISCP, DOE-WIPP 90--002, is included in this report as an appendix. The final phase of the Checkout was conducted from July 10, 1991, to July 23, 1991. This phase exercised all the procedures and equipment required to receive, emplace, and retrieve contact handled transuranium (CH TRU) waste filled dry bins. In addition, abnormal events were introduced to simulate various equipment failures, loose surface radioactive contamination events, and personnel injury. This report provides a detailed summary of each days activities during this period. Qualification of personnel to safely conduct the tasks identified in the procedures and the abnormal events were verified by observers familiar with the Bin-Scale CH TRU Waste Test requirements. These observers were members of the staffs of Westinghouse WID Engineering, QA, Training, Health Physics, Safety, and SNL. Observers representing a number of DOE departments, the state of new Mexico, and the Defense Nuclear Facilities Safety Board observed those Checkout activities conducted during the period from July 17, 1991, to July 23, 1991. Observer comments described in this report are those obtained from the staff member observers. 1 figs., 1 tab.

  1. Treatment of a maxillary central incisor with class III invasive cervical resorption and compromised ferrule: a clinical report.

    Science.gov (United States)

    Harris, Bryan T; Caicedo, Ricardo; Lin, Wei-Shao; Morton, Dean

    2014-05-01

    This clinical report presents the treatment of a maxillary central incisor with class III invasive cervical resorption and a compromised ferrule. Nonsurgical endodontic therapy combined with periodontal surgery was provided for debridement. Direct light-polymerizing resin-modified glass ionomer cement and a zirconia crown were used to repair the defect. Symptomatic endodontic complication was diagnosed with localized cone beam computed tomography at 6-month follow-up, and periapical microsurgery was rendered. The patient was followed-up for 30 months after treatment and had no further complications.

  2. Does social desirability compromise self-reports of physical activity in web-based research?

    Directory of Open Access Journals (Sweden)

    Göritz Anja S

    2011-04-01

    Full Text Available Abstract Background This study investigated the relation between social desirability and self-reported physical activity in web-based research. Findings A longitudinal study (N = 5,495, 54% women was conducted on a representative sample of the Dutch population using the Marlowe-Crowne Scale as social desirability measure and the short form of the International Physical Activity Questionnaire. Social desirability was not associated with self-reported physical activity (in MET-minutes/week, nor with its sub-behaviors (i.e., walking, moderate-intensity activity, vigorous-intensity activity, and sedentary behavior. Socio-demographics (i.e., age, sex, income, and education did not moderate the effect of social desirability on self-reported physical activity and its sub-behaviors. Conclusions This study does not throw doubt on the usefulness of the Internet as a medium to collect self-reports on physical activity.

  3. Does social desirability compromise self-reports of physical activity in web-based research?

    Science.gov (United States)

    Crutzen, Rik; Göritz, Anja S

    2011-04-14

    This study investigated the relation between social desirability and self-reported physical activity in web-based research. A longitudinal study (N = 5,495, 54% women) was conducted on a representative sample of the Dutch population using the Marlowe-Crowne Scale as social desirability measure and the short form of the International Physical Activity Questionnaire. Social desirability was not associated with self-reported physical activity (in MET-minutes/week), nor with its sub-behaviors (i.e., walking, moderate-intensity activity, vigorous-intensity activity, and sedentary behavior). Socio-demographics (i.e., age, sex, income, and education) did not moderate the effect of social desirability on self-reported physical activity and its sub-behaviors. This study does not throw doubt on the usefulness of the Internet as a medium to collect self-reports on physical activity.

  4. Does social desirability compromise self-reports of physical activity in web-based research?

    OpenAIRE

    Göritz Anja S; Crutzen Rik

    2011-01-01

    Abstract Background This study investigated the relation between social desirability and self-reported physical activity in web-based research. Findings A longitudinal study (N = 5,495, 54% women) was conducted on a representative sample of the Dutch population using the Marlowe-Crowne Scale as social desirability measure and the short form of the International Physical Activity Questionnaire. Social desirability was not associated with self-reported physical activity (in MET-minutes/week), n...

  5. Airway compromise during central venous cannulation in an undiagnosed tubercular retropharyngeal abscess: A case report

    Directory of Open Access Journals (Sweden)

    Sujay Samanta

    2015-01-01

    Full Text Available Central venous cannulation is often associated with complications during insertion even by expert′s hand and with the aid of ultrasound. We encountered a patient for central line insertion through the right internal jugular vein having a retropharyngeal abscess of tubercular origin. We accidentally punctured the abscess cavity leading to increased respiratory distress and subsequent need of intubation to the patient. This kind of complication during central line insertion has never been reported before. We intend to report such a case to alert everyone about the grave complications it can lead to and the methods to minimize them in the times ahead.

  6. System integration report

    Science.gov (United States)

    Badler, N. I.; Korein, J. D.; Meyer, C.; Manoochehri, K.; Rovins, J.; Beale, J.; Barr, B.

    1985-01-01

    Several areas that arise from the system integration issue were examined. Intersystem analysis is discussed as it relates to software development, shared data bases and interfaces between TEMPUS and PLAID, shaded graphics rendering systems, object design (BUILD), the TEMPUS animation system, anthropometric lab integration, ongoing TEMPUS support and maintenance, and the impact of UNIX and local workstations on the OSDS environment.

  7. Treatment of malpositioned periodontally compromised teeth by an interdisciplinary approach - A case report

    Directory of Open Access Journals (Sweden)

    Sonali Deshmukh

    2009-01-01

    Full Text Available The traditional orthodontic patient-base of adolescents has changed dramatically over the last 20 years. Adult patients now comprise a very large percentage of the orthodontic patient base. These patients bring with them unique challenges to the provision of aesthetic treatment. Gingival aesthetics, for a long time the exclusive concern of the periodontist, has now become one of the chief aesthetic challenges presented to the practicing orthodontist. This report illustrates the interdisciplinary approach in a patient requiring periodontic, orthodontic and prosthodontic treatment.

  8. Mixed Lineage Kinase-3 Stabilizes and Functionally Cooperates with TRIBBLES-3 to Compromise Mitochondrial Integrity in Cytokine-induced Death of Pancreatic Beta Cells*

    Science.gov (United States)

    Humphrey, Rohan K.; Newcomb, Christina J.; Yu, Shu-Mei A.; Hao, Ergeng; Yu, Doris; Krajewski, Stan; Du, Keyong; Jhala, Ulupi S.

    2010-01-01

    Mixed lineage kinases (MLKs) have been implicated in cytokine signaling as well as in cell death pathways. Our studies show that MLK3 is activated in leukocyte-infiltrated islets of non-obese diabetic mice and that MLK3 activation compromises mitochondrial integrity and induces apoptosis of beta cells. Using an ex vivo model of islet-splenocyte co-culture, we show that MLK3 mediates its effects via the pseudokinase TRB3, a mammalian homolog of Drosophila Tribbles. TRB3 expression strongly coincided with conformational change and mitochondrial translocation of BAX. Mechanistically, MLK3 directly interacted with and stabilized TRB3, resulting in inhibition of Akt, a strong suppressor of BAX translocation and mitochondrial membrane permeabilization. Accordingly, attenuation of MLK3 or TRB3 expression each prevented cytokine-induced BAX conformational change and attenuated the progression to apoptosis. We conclude that MLKs compromise mitochondrial integrity and suppress cellular survival mechanisms via TRB3-dependent inhibition of Akt. PMID:20421299

  9. Persistent Compromised Hemodynamic Function, due to single ventricular epicardial pacing, after aortic valve replacement surgery: A Case Report

    Directory of Open Access Journals (Sweden)

    Konstantinos Giakoumidakis

    2017-07-01

    Full Text Available We report the case of a 69-year old woman, who was admitted to the cardiac surgery intensive care unit (ICU of a tertiary hospital, after surgical aortic valve replacement, due to severe aortic stenosis. During the early postoperative period, the patient was hemodynamically stable and her cardiac rhythm was supported by temporary epicardial ventricular pacing. One hour after her ICU admission, the woman presented compromised hemodynamics, characterized by severe hypotension with poor response to aggressive inotropic, vasopressor and fluid therapy. After 15 minutes of her significant clinical worsening, the change of the pacing mode from single ventricular to single atrial effected immediate hemodynamic stabilization, improved arterial blood pressure and optimum patient cardiovascular function. This could be explained by the significantly reduced cardiac output in the absence of atrial contraction to assist ventricular preloading, which characterized some patients with impaired ventricular function, as those with severe aortic stenosis.

  10. Integrated reporting and board features

    Directory of Open Access Journals (Sweden)

    Rares HURGHIS

    2017-02-01

    Full Text Available In the last two decades the concept of sustainability reporting gained more importance in the companies’ annual reports, a trend which is embedded also in integrated reporting. Issuing an integrated report became a necessity, because the report explains to the investors how the organization creates value over time. The governance structure, more exactly the board of directors, decides whether or not the company will issue an integrated report. Thus, are there certain features of the board that might influence the issue of an integrated report? Do the companies which issue an integrated report have certain features of the governance structure? Looking for an answer to these questions, we seek for any possible correlations between a disclosure index and the corporate governance structure characteristics, on a sample from the companies participating at the International Integrated Reporting Council Examples Database. The results highlight that only the size of the board influences the extent to which the issued integrated report is in accordance with the International Framework.

  11. Compromised wounds in Canada.

    Science.gov (United States)

    Denny, Keith; Lawand, Christina; Perry, Sheril D

    2014-01-01

    Wounds are a serious healthcare issue with profound personal, clinical and economic implications. Using a working definition of compromised wounds, this study examines the prevalence of wounds by type and by healthcare setting using data from hospitals, home care, hospital-based continuing care and long-term care facilities within fiscal year 2011-2012 in Canada. It also evaluates several risk factors associated with wounds, such as diabetes, circulatory disease and age. Compromised wounds were reported in almost 4% of in-patient acute hospitalizations and in more than 7% of home care clients, almost 10% of long-term care clients and almost 30% of hospital-based continuing care clients. Patients with diabetes were much more likely to have a compromised wound than were patients without the disease. Copyright © 2014 Longwoods Publishing.

  12. ASEAN Integration Monitoring Report

    OpenAIRE

    ASEAN Secretariat; World Bank

    2013-01-01

    The Association of Southeast Asian Nations (ASEAN) is a community of more than 600 million people living in ten countries in one of the most dynamic regions of the world. Consistent with this, ASEAN's share of world GDP and world trade has sharply increased over the past decades. In 2003, ASEAN's regional integration agenda was significantly deepened when ASEAN Member States adopted the ambitious goal of forming an ASEAN Economic Community (AEC) by 2015. These goals were crystallized in the h...

  13. Reconstruction of advanced bone defect associated with severely compromised maxillary anterior teeth in aggressive periodontitis: a case report.

    Science.gov (United States)

    Kamil, Wisam; Al Bayati, Lina; Hussin, Akbar S; Hassan, Haszelini

    2015-09-25

    Aggressive periodontitis is characterized by a rapid rate of attachment loss and bone resorption. Regenerative therapy offers reconstruction of the periodontium; however, certain advanced cases with a questionable prognosis might remain a challenge. We report a successful intervention outcome of a challenging case in the aesthetic zone of a patient with aggressive periodontitis. A 34-year-old systemically healthy Malay woman was referred to the Periodontics Specialist Clinic of the Kulliyyah of Dentistry, International Islamic University Malaysia, with a chief complaint of bleeding gums and mobility of the upper anterior teeth. A diagnosis of localized aggressive periodontitis was made. A thorough non-surgical periodontal treatment was provided, followed by a series of regenerative periodontal surgeries to manage advanced bone defects. A successful treatment outcome with a good prognosis was achieved. Maintenance through the supportive treatment phase showed marked bone gain. Teeth with severely compromised periodontium of unpredictable prognosis can still be maintained with satisfactory restoration of the function, support, and aesthetics, despite the baseline unpredicted treatment outcome. Proper selection of an advanced periodontal treatment plan can exclude the option of tooth extraction or prosthetic replacement.

  14. [Hematological and neurological compromise due to vitamin B12 deficit in infant of a vegetarian mother: case report].

    Science.gov (United States)

    Bravo J, Paulina; Ibarra C, Judith; Paredes M, Marcela

    2014-06-01

    Vitamin B12 deficiency is extremely common in strict vegetarians and their variants. Infants of vegetarian mothers have a higher risk of deficiency and are more prone to its effects. To report a case in order to warn people about the importance of suspected vitamin B12 deficiency in children of vegetarian mothers. A 12-month old infant, daughter of a longtime vegetarian woman, who presented neurological and hematological compromise due to vitamin B12 deficiency, is discussed. After a short period of parenteral administration of cyanocobalamin and enteral nutrition, the patient evolved with clinical and laboratory improvement, although she still had residual development delay. Vitamin B12 deficiency is often not suspected by the pediatrician in healthy infants. Clinical manifestations can be nonspecific, such as apathy, food refusal and progressive impairment of psychomotor development. A nutritional anamnesis performed on the mother (with great emphasis on those strict vegetarians) to estimate her reserves in the period prior to, during and after delivery can be critical to detect the risk of this vitamin deficiency in young children.

  15. Mixed Lineage Kinase-3 Stabilizes and Functionally Cooperates with TRIBBLES-3 to Compromise Mitochondrial Integrity in Cytokine-induced Death of Pancreatic Beta Cells*

    OpenAIRE

    Humphrey, Rohan K.; Newcomb, Christina J.; Yu, Shu-Mei A.; Hao, Ergeng; Yu,Doris; Krajewski, Stan; Du, Keyong; Jhala, Ulupi S.

    2010-01-01

    Mixed lineage kinases (MLKs) have been implicated in cytokine signaling as well as in cell death pathways. Our studies show that MLK3 is activated in leukocyte-infiltrated islets of non-obese diabetic mice and that MLK3 activation compromises mitochondrial integrity and induces apoptosis of beta cells. Using an ex vivo model of islet-splenocyte co-culture, we show that MLK3 mediates its effects via the pseudokinase TRB3, a mammalian homolog of Drosophila Tribbles. TRB3 expression strongly coi...

  16. A model of integrated lung and focused heart ultrasound as a new screening examination in infants at risk of respiratory or hemodynamic compromise

    Directory of Open Access Journals (Sweden)

    Yasser Elsayed

    2017-02-01

    Full Text Available Objective: This was a feasibility study to determine whether an edu­cational program conducted over 2 days followed by 25 performed studies under supervision equips physicians with the skills to accurately interpret and perform integrated lung ultrasound (LUS and focused heart ultrasound (FHUS as a screening exam in infants at risk of respiratory or hemodynamic compromise.Methods: We conducted a training course over 2 days (total of 16 hours to teach fellows how to interpret a pre-designed model of LUS and FHUS, as a screening exam for infants at risk of respiratory or hemodynamic compromise. Then trainees performed 25 cases with different neonatal lung and functional heart issues. The screening model included only the basic views required to evaluate common lung parenchymal and functional neonatal heart conditions in sick infants. The accuracy of interpretation during the course was assessed by Kappa.Results: The inter-rater agreement between all trainees and instructor improved on the second day of the course to Kappa 0.86 (95% CI: 0.72-0.97 for LUS views and 0.78 (95% CI: 0.69-0.91 for FHUS views. The inter-rater agreement between trainees themselves improved from Kappa 0.64 (95% CI: 0.47-0.81 for LUS on day one to 0.89 (95% CI: 0.81-0.96 on day two. And from 0.58 (95% CI: 0.44-0.73 on day one to 0.75 (95% CI: 0.68-0.84 on day two.Conclusion: Bedside screening, using integrated LUS and FHUS can be a useful adjunct to clinical examination in infants at risk of respiratory or hemodynamic compromise.

  17. Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report.

    Science.gov (United States)

    Clement, Nicholas D; Goswami, Anukul

    2009-06-29

    We present a case of a Salter-Harris II injury to the proximal tibia associated with both vascular compromise and compartment syndrome. The potential complications of this injury are limb threatening and the neurovasular status of the limb should be continually monitored. Maintaining anatomic reduction is difficult and fixation may be needed to achieve optimal results.

  18. Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report

    OpenAIRE

    Clement Nicholas D; Goswami Anukul

    2009-01-01

    Abstract We present a case of a Salter-Harris II injury to the proximal tibia associated with both vascular compromise and compartment syndrome. The potential complications of this injury are limb threatening and the neurovasular status of the limb should be continually monitored. Maintaining anatomic reduction is difficult and fixation may be needed to achieve optimal results.

  19. Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report

    Directory of Open Access Journals (Sweden)

    Clement Nicholas D

    2009-06-01

    Full Text Available Abstract We present a case of a Salter-Harris II injury to the proximal tibia associated with both vascular compromise and compartment syndrome. The potential complications of this injury are limb threatening and the neurovasular status of the limb should be continually monitored. Maintaining anatomic reduction is difficult and fixation may be needed to achieve optimal results.

  20. Integrated reporting with CSR practices

    DEFF Research Database (Denmark)

    Lueg, Klarissa; Lueg, Rainer; Andersen, Karina;

    2016-01-01

    Purpose: This study aims to illustrate how standards and guidelines for corporate social responsibility (CSR) can help a company in its integrated reporting (IR). We investigate the motivations of diverse stakeholders (including shareholders) in fostering the adoption of standards and guidelines...... for CSR after IR became mandatory in Denmark. Methodology: We conduct a case study at the Danish carpet manufacturer EGE. We interpret the case from the perspective of pragmatic constructivism, which focuses on the integration of four dimensions: facts, possibilities, values, and communication. Findings......: We find that the family-owned EGE follows a strategy of “enlightened shareholder value”, in which CSR is an essential value driver. This strategy fostered IR with guidelines and standards for CSR. The CSR practices appeared to be helpful for integrating measureable plans to the strategy...

  1. Cavalieri Integration - CSIR Technical report

    CSIR Research Space (South Africa)

    Grobler, TL

    2011-10-01

    Full Text Available The authors use Cavalieri's principle to develop a novel integration technique which they call Cavalieri integration. Cavalieri integrals differ from Riemann integrals in that non-rectangular integration strips are used. In this way they can use...

  2. Compromise and Toleration

    DEFF Research Database (Denmark)

    Rostbøll, Christian F.

    Political compromise is akin to toleration, since both consist of an "agreement to disagree." Compromise and toleration also share a predicament of being regarded as ambiguous virtues that require of us to accept something we actually regard as wrong. However, we misunderstand the nature......, justification, and limits of compromise if we see it merely as a matter of toleration. While toleration is mainly a matter of accepting citizens' equal right to co-existence as subjects to law, political compromise includes the parties in making law – it makes them co-authors of law. Toleration entails...... respecting the plurality of conceptions of the good in society, whereas political compromise embodies the disagreements in coercive laws. This difference between toleration and compromise has two important consequences. First, political compromise is justified in a different manner than is toleration...

  3. Fostering innovation without compromising integrity.

    Science.gov (United States)

    Pizzo, Philip A

    2007-03-01

    Industry's interaction with academia has created vast opportunity for innovation but also the potential for undue financial influence. Potential conflicts of interest can occur at the level of the individual researcher or the institution. Implementing guidelines and policies on conflicts of interest can help maintain appropriate separation between academic medicine and industry while permitting medical innovation to proceed. In an effort to retain public trust, Stanford University School of Medicine has enacted policies to identify and manage potential conflicts among its faculty, to divest of holdings in companies conducting studies involving Stanford investigators, and to ban all industry marketing and gifts from Stanford facilities.

  4. The effect of integrated reporting on integrated thinking between risk ...

    African Journals Online (AJOL)

    The effect of integrated reporting on integrated thinking between risk, opportunity and strategy and the disclosure of risks and ... Southern African Business Review ... For this purpose, a web-based research questionnaire was sent to high-level ...

  5. Integrated sequence analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, K.; Pyy, P

    1998-02-01

    The NKS/RAK subprojet 3 `integrated sequence analysis` (ISA) was formulated with the overall objective to develop and to test integrated methodologies in order to evaluate event sequences with significant human action contribution. The term `methodology` denotes not only technical tools but also methods for integration of different scientific disciplines. In this report, we first discuss the background of ISA and the surveys made to map methods in different application fields, such as man machine system simulation software, human reliability analysis (HRA) and expert judgement. Specific event sequences were, after the surveys, selected for application and testing of a number of ISA methods. The event sequences discussed in the report were cold overpressure of BWR, shutdown LOCA of BWR, steam generator tube rupture of a PWR and BWR disturbed signal view in the control room after an external event. Different teams analysed these sequences by using different ISA and HRA methods. Two kinds of results were obtained from the ISA project: sequence specific and more general findings. The sequence specific results are discussed together with each sequence description. The general lessons are discussed under a separate chapter by using comparisons of different case studies. These lessons include areas ranging from plant safety management (design, procedures, instrumentation, operations, maintenance and safety practices) to methodological findings (ISA methodology, PSA,HRA, physical analyses, behavioural analyses and uncertainty assessment). Finally follows a discussion about the project and conclusions are presented. An interdisciplinary study of complex phenomena is a natural way to produce valuable and innovative results. This project came up with structured ways to perform ISA and managed to apply the in practice. The project also highlighted some areas where more work is needed. In the HRA work, development is required for the use of simulators and expert judgement as

  6. Reconstruction of advanced bone defect associated with severely compromised maxillary anterior teeth in aggressive periodontitis: a case report

    OpenAIRE

    Kamil, Wisam; Al Bayati, Lina; Hussin, Akbar S.; Hassan, Haszelini

    2015-01-01

    Introduction Aggressive periodontitis is characterized by a rapid rate of attachment loss and bone resorption. Regenerative therapy offers reconstruction of the periodontium; however, certain advanced cases with a questionable prognosis might remain a challenge. We report a successful intervention outcome of a challenging case in the aesthetic zone of a patient with aggressive periodontitis. Case presentation A 34-year-old systemically healthy Malay woman was referred to the Periodontics Spec...

  7. State Program Integrity Review Reports List

    Data.gov (United States)

    U.S. Department of Health & Human Services — Comprehensive state program integrity (PI) review reports (and respective follow-up review reports) provide CMS assessment of the effectiveness of the states PI...

  8. The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients

    DEFF Research Database (Denmark)

    Jensen, Martin Borch; Dunn, Christopher A; Keijzers, Guido

    2012-01-01

    RECQL4 is one of five members of the human RecQ helicase family, and is implicated in three syndromes displaying accelerating aging, developmental abnormalities and a predisposition to cancer. In this study, we purified three variants of RECQL4 carrying previously reported patient mutations....... These three mutant proteins were analyzed for the known biochemical activities of RECQL4: DNA binding, unwinding of duplex DNA, ATP hydrolysis and annealing of simplex DNA. Further, the mutant proteins were evaluated for stability and recruitment to sites of laser-induced DNA damage. One mutant was helicase...... a consistent pattern of functional deficiency and provide further support for a helicase-dependent cellular function of RECQL4 in addition to its N-terminus-dependent role in initiation of replication, a function that may underlie the phenotype of RECQL4-linked disease....

  9. Compromises of Bali Roadmap

    Institute of Scientific and Technical Information of China (English)

    Wang Jingmin; Wei Dong

    2008-01-01

    The Bali Roadmap, as the breakthrough on intergovernmental negotiation of climate change mitigation, having brought United States on track, is still a result of compromises. The major compromises of the Bali Roadmap are centered around three issues of quantifying emission reduction targets, developing countries' obligations as well as quantifying developed countries' financial assistance in developing countries' capacity building on climate change. It is found that the rationalities behind these compromises are the national interests. Due to the fact, achieving cohesion among all nations in climate change actions is very difficult. Therefore, the Bali Roadmap may lead to a tough way with distant hope. However, technology innovation and well-designed economic instruments would be helpful and supportive for further international negotiation and cooperation.

  10. INTEGRATED REPORTING - THE FUTURE OF FINANCIAL REPORTING

    OpenAIRE

    Diana Sabina COZMA IGHIAN

    2015-01-01

    From investors’ point of view, financial results are not sufficient to offer an overview of a given business. To provide an overview on the activity of an entity, reports will need to include both the traditional financial and non-financial part to provide information on sustainable development, the impact of the activity on the environment, and social responsibility.\\r\

  11. A new dimension of the entities’ financial reporting: Integrated Reporting

    Directory of Open Access Journals (Sweden)

    LAPTES Ramona

    2017-01-01

    Full Text Available Nowadays, the development strategy of big corporations is based on the principle of sustainable development, which includes both protecting the interests of all involved economic actors and minimizing the aggression on natural resources. In this context, the financial communication process in large companies has acquired new meanings, being reconsidered and taking the form of Integrated Reporting. The objective of this paper is to develop a study regarding the theory of Integrated Reporting, based on a documentary research on the reports published by the International Integrated Reporting Council and organizations such as KPMG, E&Y or ACCA. Integrated Reporting is a new practice, still under development and in expansion at international level. An integrated report tells the story of a company’s journey towards achieving its vision and provides information about its historical performance, but also about the expected one.

  12. Organizational aspects of integrated reporting preparation according to international standard «Integrated reporting»

    Directory of Open Access Journals (Sweden)

    M.O. Maksymchuk

    2016-12-01

    Full Text Available Integrated Reporting is an innovative reporting for business entities, therefore the issue of the organization the preparation of this reporting is an actual. The absence of legislative regulation of integrated reporting at national level of legal documents has greatly affected the issue, because the only document, that specifies the requirements for integrated reporting is the international standard «integrated reporting». The article considers the organizational principles of integrated reporting preparation. Taking into account the requirements of the international standard «integrated reporting», the authors make the attempts to define the basic organizational stages of such reporting, that allows to introduce the integrated reporting in a structured way and logically. It is proposed on the enterprises preparing the integrated reporting to constitute the schedule of the formation of the integrated reporting. In addition, the important thing is to develop the internal policy for determining materiality by the use of the professional judgment. The appropriate internal policy is assigned to disclose the materiality process in an integrated reporting for decision-making on the inclusion or exclusion issues to be understandable for users.

  13. Community for Data Integration 2016 annual report

    Science.gov (United States)

    Langseth, Madison L.; Hsu, Leslie; Amberg, Jon; Bliss, Norman; Bock, Andrew R.; Bolus, Rachel T.; Bristol, R. Sky; Chase, Katherine J.; Crimmins, Theresa M.; Earle, Paul S.; Erickson, Richard; Everette, A. Lance; Falgout, Jeff T.; Faundeen, John L.; Fienen, Michael N.; Griffin, Rusty; Guy, Michelle R.; Henry, Kevin D.; Hoebelheinrich, Nancy J.; Hunt, Randall; Hutchison, Vivian B.; Ignizio, Drew A.; Infante, Dana M.; Jarnevich, Catherine; Jones, Jeanne M.; Kern, Tim; Leibowitz, Scott; Lightsom, Francis L.; Marsh, R. Lee; McCalla, S. Grace; McNiff, Marcia; Morisette, Jeffrey T.; Nelson, John C.; Norkin, Tamar; Preston, Todd M.; Rosemartin, Alyssa; Sando, Roy; Sherba, Jason T.; Signell, Richard P.; Sleeter, Benjamin M.; Sundquist, Eric T.; Talbert, Colin B.; Viger, Roland J.; Weltzin, Jake F.; Waltman, Sharon; Weber, Marc; Wieferich, Daniel J.; Williams, Brad; Windham-Myers, Lisamarie

    2017-05-19

    The Community for Data Integration (CDI) represents a dynamic community of practice focused on advancing science data and information management and integration capabilities across the U.S. Geological Survey and the CDI community. This annual report describes the various presentations, activities, and outcomes of the CDI monthly forums, working groups, virtual training series, and other CDI-sponsored events in fiscal year 2016. The report also describes the objectives and accomplishments of the 13 CDI-funded projects in fiscal year 2016.

  14. Integrated Reporting for a Good Corporate Governance

    Directory of Open Access Journals (Sweden)

    Bobitan Roxana-Ioana

    2017-01-01

    This help a company to reporting how its governance structure supports the organization’sability to create the value in the short, medium and long term and the integrated report can be usedas a corporate governance tool. The aim of this discussion paper is to describe these new conceptsand also, relationship between these.

  15. Preliminary Integrated Safety Analysis Status Report

    Energy Technology Data Exchange (ETDEWEB)

    D. Gwyn

    2001-04-01

    This report provides the status of the potential Monitored Geologic Repository (MGR) Integrated Safety Analysis (EA) by identifying the initial work scope scheduled for completion during the ISA development period, the schedules associated with the tasks identified, safety analysis issues encountered, and a summary of accomplishments during the reporting period. This status covers the period from October 1, 2000 through March 30, 2001.

  16. Impending Airway Compromise due to Cystic Hygroma

    Directory of Open Access Journals (Sweden)

    Itai Shavit

    2011-05-01

    Full Text Available We report on a 3-month-old infant, who arrived in the pediatric emergency department (ED with a cervical cystic hygroma causing an impending compromise of the airway. We recognize that such a lesion can rapidly progress, and the judicious use of imaging in the ED may help to avoid airway compromise and possibly fatal complications. [West J Emerg Med. 2011;12(4:368–369.

  17. National Report presented by the Mexican United States to satisfy the compromises of the Nuclear Safety Convention; Informe Nacional que presentan los Estados Unidos Mexicanos para satisfacer los compromisos de la Convencion de Seguridad Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    National Commission of Nuclear Safety and Safeguards, Mexico City (Mexico); Federal Commission for Electricity, Mexico City (Mexico)

    1998-12-31

    In order to satisfy to the compromises derived of the ratification by part of the Mexican Government for the Nuclear Safety Convention it is presented this National Report which is based on the directives proposed as a result of the preparatory meetings held in the IAEA Headquarters in the city of Vienna, Austria. This National Report represents a document summary and activities realized at present in relation with the only nuclear facility in Mexico: the Nuclear Power Plant in Laguna Verde, Veracruz. This report consists of two parts: In the first one it is described how have been satisfied each one of the compromises. The second one talks about the Laws and Regulations on nuclear activities in the country. (Author)

  18. AFM visualization of sub-50nm polyplex disposition to the nuclear pore complex without compromising the integrity of the nuclear envelope.

    Science.gov (United States)

    Andersen, Helene; Parhamifar, Ladan; Hunter, A Christy; Shahin, Victor; Moghimi, S Moein

    2016-12-28

    It has been questioned as to whether polyplexes in the cytoplasm can reach the nuclear compartment and if so in what form. By applying atomic force microscopy (AFM) to the nuclear envelope and the nuclear pore complexes, we demonstrate that disposition of polyethylenimine (PEI)/DNA polyplexes that were microinjected into the oocytes of Xenopus laevis, as an example of a non-dividing cell, is exclusive to the nuclear pore complex (NPC). AFM images show NPCs clogged only with sub-50nm polyplexes. This mode of disposition neither altered the morphology/integrity of the nuclear membrane nor the NPC. AFM images further show polyplexes on the nucleoplasmic side of the envelope, presumably indicating species in transit. Transmission electron microscopy studies of ruptured nuclei from transfected human cell lines demonstrate the presence of sub-50nm particles resembling polyplexes in morphology compared with control preparations.

  19. Solar thermal repowering systems integration. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Dubberly, L. J.; Gormely, J. E.; McKenzie, A. W.

    1979-08-01

    This report is a solar repowering integration analysis which defines the balance-of-plant characteristics and costs associated with the solar thermal repowering of existing gas/oil-fired electric generating plants. Solar repowering interface requirements for water/steam and salt or sodium-cooled central receivers are defined for unit sizes ranging from 50 MWe non-reheat to 350 MWe reheat. Finally balance-of-plant cost estimates are presented for each of six combinations of plant type, receiver type and percent solar repowering.

  20. Uneasy Compromise: Language and Education in Moldova

    Science.gov (United States)

    Ciscel, Matthew

    2008-01-01

    This study reports on the uneasy compromise in language and education policies in the post-Soviet Republic of Moldova since its first moves toward independence in 1989. Taking an approach that posits language policies as needing to be anchored in both international norms and the idiosyncrasies of local conditions, the discussion explores the…

  1. Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.

    Science.gov (United States)

    Brammer Basta, Leighanne A; Ghosh, Anita; Pan, Ying; Jakoncic, Jean; Lloyd, Evan P; Townsend, Craig A; Lamichhane, Gyanu; Bianchet, Mario A

    2015-10-16

    The final step of peptidoglycan (PG) biosynthesis in bacteria involves cross-linking of peptide side chains. This step in Mycobacterium tuberculosis is catalyzed by ld- and dd-transpeptidases that generate 3→3 and 4→3 transpeptide linkages, respectively. M. tuberculosis PG is predominantly 3→3 cross-linked, and LdtMt2 is the dominant ld-transpeptidase. There are four additional sequence paralogs of LdtMt2 encoded by the genome of this pathogen, and the reason for this apparent redundancy is unknown. Here, we studied one of the paralogs, LdtMt5, and found it to be structurally and functionally distinct. The structures of apo-LdtMt5 and its meropenem adduct presented here demonstrate that, despite overall architectural similarity to LdtMt2, the LdtMt5 active site has marked differences. The presence of a structurally divergent catalytic site and a proline-rich C-terminal subdomain suggest that this protein may have a distinct role in PG metabolism, perhaps involving other cell wall-anchored proteins. Furthermore, M. tuberculosis lacking a functional copy of LdtMt5 displayed aberrant growth and was more susceptible to killing by crystal violet, osmotic shock, and select carbapenem antibiotics. Therefore, we conclude that LdtMt5 is not a functionally redundant ld-transpeptidase, but rather it serves a unique and important role in maintaining the integrity of the M. tuberculosis cell wall.

  2. Integrated reporting – innovation in accounting paradigms

    Directory of Open Access Journals (Sweden)

    Mirosława Kwiecień

    2016-07-01

    Full Text Available The article is an introduction to the issues and results of a new trend in interdisciplinary research, which is integrated reporting. „Violated balance”, characteristic of contemporary global economy, forces us to seek solutions oriented to symbiosis between economic, social and environmental progress, which is the basis for fundamental changes in mental models that determine the way the economic organization oper-ates. On the basis of literature studies, as well as management (of innovation, knowledge, etc. science studies and research on changes in legal regulations of accounting, one can venture to say that the change in accounting paradigms is an innovation which stems from legal requirements. Legislation stimulates conceptuality, including information management, standardization of accounting, etc. Innovation theory refers to technological, organizational and market changes, so a question ariseswhether this theory can be applied to accounting practices as well? In this way an idea emerged for inves-tigating the question if the implementation of legal regulations such as International Financial Reporting Standards (IFRS or the standards of the Global Reporting Initiative (GRI is a manifestation of the inno-vation theory in the development of accounting systems, especially in reporting.

  3. A report on reporting: Why peers report integrity and law violations in public organizations

    NARCIS (Netherlands)

    Graaf, de G.

    2010-01-01

    The archives of three bureaus of integrity are analyzed in order to study the reasons for reporting integrity and law violations within public organizations. Peer reporting accounts for only a small percentage of cases; most investigations originate from routine and continuous institutional controls

  4. Integrated environmentally compatible soldering technologies. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hosking, F.M.; Frear, D.R.; Iman, R.L.; Keicher, D.M.; Lopez, E.P.; Peebles, H.C.; Sorensen, N.R.; Vianco, P.T.

    1994-05-01

    Chemical fluxes are typically used during conventional electronic soldering to enhance solder wettability. Most fluxes contain very reactive, hazardous constituents that require special storage and handling. Corrosive flux residues that remain on soldered parts can severely degrade product reliability. The residues are removed with chlorofluorocarbon (CFC), hydrochlorofluorocarbon (HCFC), or other hazardous solvents that contribute to ozone depletion, release volatile organic compounds into the atmosphere, or add to the solvent waste stream. Alternative materials and processes that offer the potential for the reduction or elimination of cleaning are being developed to address these environmental issues. Timing of the effort is critical, since the targeted chemicals will soon be heavily taxed or banned. DOE`s Office of Environmental Restoration and Waste Management (DOE/EM) has supported Sandia National Laboratories` Environmentally Conscious Manufacturing Integrated Demonstration (ECMID). Part of the ECM program involves the integration of several environmentally compatible soldering technologies for assembling electronics devices. Fluxless or {open_quotes}low-residue/no clean{close_quotes} soldering technologies (conventional and ablative laser processing, controlled atmospheres, ultrasonic tinning, protective coatings, and environmentally compatible fluxes) have been demonstrated at Sandia (SNL/NM), the University of California at Berkeley, and Allied Signal Aerospace-Kansas City Division (AS-KCD). The university demonstrations were directed under the guidance of Sandia staff. Results of the FY93 Soldering ID are presented in this report.

  5. Integrated Data Base Program: a status report

    Energy Technology Data Exchange (ETDEWEB)

    Notz, K.J.; Klein, J.A.

    1984-06-01

    The Integrated Data Base (IDB) Program provides official Department of Energy (DOE) data on spent fuel and radioactive waste inventories, projections, and characteristics. The accomplishments of FY 1983 are summarized for three broad areas: (1) upgrading and issuing of the annual report on spent fuel and radioactive waste inventories, projections, and characteristics, including ORIGEN2 applications and a quality assurance plan; (2) creation of a summary data file in user-friendly format for use on a personal computer and enhancing user access to program data; and (3) optimizing and documentation of the data handling methodology used by the IDB Program and providing direct support to other DOE programs and sites in data handling. Plans for future work in these three areas are outlined. 23 references, 11 figures.

  6. Vehicle Integrated Prognostic Reasoner (VIPR) Metric Report

    Science.gov (United States)

    Cornhill, Dennis; Bharadwaj, Raj; Mylaraswamy, Dinkar

    2013-01-01

    This document outlines a set of metrics for evaluating the diagnostic and prognostic schemes developed for the Vehicle Integrated Prognostic Reasoner (VIPR), a system-level reasoner that encompasses the multiple levels of large, complex systems such as those for aircraft and spacecraft. VIPR health managers are organized hierarchically and operate together to derive diagnostic and prognostic inferences from symptoms and conditions reported by a set of diagnostic and prognostic monitors. For layered reasoners such as VIPR, the overall performance cannot be evaluated by metrics solely directed toward timely detection and accuracy of estimation of the faults in individual components. Among other factors, overall vehicle reasoner performance is governed by the effectiveness of the communication schemes between monitors and reasoners in the architecture, and the ability to propagate and fuse relevant information to make accurate, consistent, and timely predictions at different levels of the reasoner hierarchy. We outline an extended set of diagnostic and prognostics metrics that can be broadly categorized as evaluation measures for diagnostic coverage, prognostic coverage, accuracy of inferences, latency in making inferences, computational cost, and sensitivity to different fault and degradation conditions. We report metrics from Monte Carlo experiments using two variations of an aircraft reference model that supported both flat and hierarchical reasoning.

  7. The readability of international illustration of auditor’s report: An advanced reflection on the compromise between normative principles and linguistic requirements

    Directory of Open Access Journals (Sweden)

    Mondher Fakhfakh

    2015-06-01

    Full Text Available The independent auditors periodically publish reports that summarize the audit results. These reports reinforce the financial communication and reliability of accounting information. International Standards on Auditing (ISA determine the content of audit reports and the quality of audit results. Theoretically, the audit standardization must model intelligible and clear reports for readers. Compliance with linguistic principles contributes to the improvement of the structure of audit reports. In practice, the effectiveness of these reports is criticized because users do not understand the audit information. In order to improve the content of audit reports, International Federation of Accountants (IFAC had revised International Standards on Auditor’s report: ISA 700: Forming an opinion and reporting on financial statements. Linguistically, standardized audit reports could be unreadable by many users of financial statements. This article discusses the linguistic problems related to the preparation of reports. This discussion focuses on the audit reports which are illustrated by the International Standards on Auditing. The results show that in the presence of conflicting requirements (auditing standards versus linguistic principles, independent auditors must optimize the presentation of their reports.

  8. NEW CORPORATE REPORTING TRENDS. ANALYSIS ON THE EVOLUTION OF INTEGRATED REPORTING

    Directory of Open Access Journals (Sweden)

    Dragu Ioana

    2013-07-01

    Full Text Available The objective of this paper is to present the new corporate reporting trends of the 21st century. Integrated reporting has been launched through a common initiative of the International Integrated Reporting Committee and global accounting organizations. However, the history of integrated reports starts before the initiative of the IIRC, and goes back in time when large corporations begun to disclose sustainability and corporate social responsibility information. Further on, we claim that the initial sustainability and CSR reports that were issued separate along with the financial annual report represent the predecessors of the current integrated reports. The paper consists of a literature review analysis on the evolution of integrated reporting, from the first stage of international non-financial initiatives, up to the current state of a single integrated annual report. In order to understand the background of integrated reporting we analyze the most relevant research papers on corporate reporting, focusing on the international organizations’ perspective on non-financial reporting, in general, and integrated reporting, in particular. Based on the literature overview, we subtracted the essential information for setting the framework of the integrated reporting evolution. The findings suggest that we can delimitate three main stages in the evolution of integrated reports, namely: the non-financial reporting initiatives, the sustainability era, and the revolution of integrated reporting. We illustrate these results by presenting each relevant point in the history of integrated reporting on a time scale axis, developed with the purpose of defining the road to integrated reporting at theoretical, empirical, and practical levels. We consider the current investigation as relevant for future studies concerning integrated reports, as this is a new area of research still in its infancy. The originality of the research derives from the novelty of

  9. Compromise and Disagreement in Comtemporary Political Theory

    DEFF Research Database (Denmark)

    Rostbøll, Christian F.; Scavenius, Theresa

    Compromise and Disagreement in Contemporary Political Theory provides a critical discussion of when and to what extent compromise is the best response to pluralism and disagreement in democratic decision-making and beyond. Organized into four parts, the book begins by discussing the justification...... and limits of compromise. Part II discusses the practice of compromise and considers the ethics required for compromise as well as the institutions that facilitate compromise. Part III focuses on pluralism and connects the topic of compromise to current discussions in political theory on public reason......, political liberalism, and respect for diversity. Part IV discusses different challenges to compromise in the context of the current political environment....

  10. Flow-based compromise detection

    NARCIS (Netherlands)

    Hofstede, Rick

    2016-01-01

    Brute-force attacks are omnipresent and manyfold on the Internet, and aim at compromising user accounts by issuing large numbers of authentication attempts on applications and daemons. Widespread targets of such attacks are Secure SHell (SSH) and Web applications, for example. The impact of brute-fo

  11. Community for Data Integration 2014 annual report

    Science.gov (United States)

    Langseth, Madison L.; Chang, Michelle Y.; Carlino, Jennifer; Birch, Daniella D.; Bradley, Joshua; Bristol, R. Sky; Conzelmann, Craig; Diehl, Robert H.; Earle, Paul S.; Ellison, Laura E.; Everette, Anthony L.; Fuller, Pam L.; Gordon, Janice M.; Govoni, David L.; Guy, Michelle R.; Henkel, Heather S.; Hutchison, Vivian B.; Kern, Tim; Lightsom, Frances L.; Long, Joseph W.; Longhenry, Ryan; Preston, Todd M.; Smith, Stan W.; Viger, Roland J.; Wesenberg, Katherine; Wood, Eric C.

    2015-10-02

    The U.S. Geological Survey (USGS) researches Earth science to help address complex issues affecting society and the environment. In 2006, the USGS held the first Scientific Information Management Workshop to bring together staff from across the organization to discuss the data and information management issues affecting the integration and delivery of Earth science research and investigate the use of “communities of practice” as mechanisms to share expertise about these issues. Out of this effort emerged the Council for Data Integration, which was conceived as an official organizational function that would help guide data integration activities and formalize communities of practice into working groups; however, by 2009 it became evident that many members of the Council for Data Integration had an interest in developing data integration solutions and sharing expertise in a less formal, grassroots manner, which transformed the Council into a Community for Data Integration (CDI). As of 2014, the CDI represents a dynamic community of practice focused on advancing science data and information management and integration capabilities across the USGS and the CDI community.

  12. Senior executives' perspectives of integrated reporting regulatory ...

    African Journals Online (AJOL)

    kirstam

    2014-12-09

    Dec 9, 2014 ... as valuable relevant information for shareholders' decision-making (De Klerk & De ..... is integrated into the decision-making process, the drivers of ...... 'The age of consumer capitalism', Harvard Business Review, January–.

  13. The integrated reporting: A presentation of the current state of art and aspects of integrated reporting that need further development

    OpenAIRE

    Jordi Morros

    2016-01-01

    Purpose: The purpose of this paper is to synthesise what is the emerging field of integrated reporting, with particular emphasis in the International Integrated Reporting Council, and outline a list of items for future research in this area. Design/methodology/approach: The approach is to outline a presentation of integrated reporting (IR), and make a review of the implications for the research agenda of the most important items. Findings: The need for quality researchers to address a number ...

  14. Community for Data Integration 2013 Annual Report

    Science.gov (United States)

    Chang, Michelle Y.; Carlino, Jennifer; Barnes, Christopher; Blodgett, David L.; Bock, Andrew R.; Everette, Anthony L.; Fernette, Gregory L.; Flint, Lorraine E.; Gordon, Janice M.; Govoni, David L.; Hay, Lauren E.; Henkel, Heather S.; Hines, Megan K.; Holl, Sally L.; Homer, Collin G.; Hutchison, Vivian B.; Ignizio, Drew A.; Kern, Tim J.; Lightsom, Frances L.; Markstrom, Steven L.; O'Donnell, Michael S.; Schei, Jacquelyn L.; Schmid, Lorna A.; Schoephoester, Kathryn M.; Schweitzer, Peter N.; Skagen, Susan K.; Sullivan, Daniel J.; Talbert, Colin; Warren, Meredith Pavlick

    2015-01-01

    The U.S. Geological Survey (USGS) conducts earth science to help address complex issues affecting society and the environment. In 2006, the USGS held the first Scientific Information Management Workshop to bring together staff from across the organization to discuss the data and information management issues affecting the integration and delivery of earth science research and investigate the use of “communities of practice” as mechanisms to share expertise about these issues. Out of this effort emerged the Council for Data Integration, which was conceived as an official organizational function that would help guide data integration activities and formalize communities of practice into working groups. However by 2009, it became apparent that many members of the council had an interest in developing data integration solutions and sharing expertise in a less formal grassroots perspective, thus transforming the “Council” into a “Community” for Data Integration (CDI). Today, the CDI represents a dynamic community of practice focused on advancing science data and information management and integration capabilities across the USGS and the CDI community.

  15. THE MANAGEMENT ACCOUNTING TOOLS AND THE INTEGRATED REPORTING

    OpenAIRE

    Gabriel JINGA; Mădălina DUMITRU

    2015-01-01

    During the recent years the stakeholders are asking for other pieces of information to be published along with the financial one, such as risk reporting, intangibles, social and environmental accounting. The type of corporate reporting which incorporates the elements enumerated above is the integrated reporting. In this article, we argue that the information disclosed in the integrated reports is prepared by the management accounting, not only by the financial accounting. Thus, we search for ...

  16. Immune Compromise in HIV-1/HTLV-1 Coinfection With Paradoxical Resolution of CD4 Lymphocytosis During Antiretroviral Therapy: A Case Report.

    Science.gov (United States)

    Rockwood, N; Cook, L; Kagdi, H; Basnayake, S; Bangham, C R M; Pozniak, A L; Taylor, G P

    2015-12-01

    Human immunodeficiency virus type-1 (HIV-1) and human T lymphotropic virus type-1 (HTLV-1) infections have complex effects on adaptive immunity, with specific tropism for, but contrasting effects on, CD4 T lymphocytes: depletion with HIV-1, proliferation with HTLV-1. Impaired T lymphocyte function occurs early in HIV-1 infection but opportunistic infections (OIs) rarely occur in the absence of CD4 lymphopenia. In the unusual case where a HIV-1 infected individual with a high CD4 count presents with recurrent OIs, a clinician is faced with the possibility of a second underlying comorbidity. We present a case of pseudo-adult T cell leukemia/lymphoma (ATLL) in HIV-1/HTLV-1 coinfection where the individual fulfilled Shimoyama criteria for chronic ATLL and had pulmonary Mycobacterium kansasii, despite a high CD4 lymphocyte count. However, there was no evidence of clonal T-cell proliferation by T-cell receptor gene rearrangement studies nor of monoclonal HTLV-1 integration by high-throughput sequencing. Mutually beneficial interplay between HIV-1 and HTLV-1, maintaining high level HIV-1 and HTLV-1 viremia and proliferation of poorly functional CD4 cells despite chronicity of infection is a postulated mechanism. Despite good microbiological response to antimycobacterial therapy, the patient remained systemically unwell with refractory anemia. Subsequent initiation of combined antiretroviral therapy led to paradoxical resolution of CD4 T lymphocytosis as well as HIV-1 viral suppression and decreased HTLV-1 proviral load. This is proposed to be the result of attenuation of immune activation post-HIV virological control. This case illustrates the importance of screening for HTLV-1 in HIV-1 patients with appropriate clinical presentation and epidemiological risk factors and explores mechanisms for the complex interactions on HIV-1/HTLV-1 adaptive immunity.

  17. Integrated Pest Management. A Curriculum Report.

    Science.gov (United States)

    McCabe, Robert H., Ed.; And Others

    This book consists of materials prepared for a conference aimed at developing courses of study in Integrated Pest Management appropriate for use at several levels: secondary schools, MDTA programs, community colleges and technical institutions, baccalaureate programs, and master's and doctoral level programs. The first section (Background Papers)…

  18. 2009 Integrated Biorefinery Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program‘s Integrated Biorefinery (IBR) platform review meeting, held on February 18–19, 2009, at the Westin National Harbor, National Harbor, Maryland.

  19. Preoccupations in the Field of Integrated Reporting

    OpenAIRE

    Enachi Mihaela

    2011-01-01

    A growing number of organizations offer through the reports prepared at the end of the financial year, in addition to financial information, more and more non-financial information. In this paper we try to clarify what makes the difference between these two categories of information, why is necessary to provide non-financial information and how is it reported. We also bring into discussion some references existing in the international accounting regulations, European directives and Romanian a...

  20. Environmentally conscious manufacturing integrated demonstration. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Gentry, D.E.

    1993-07-01

    The objective of the Environmentally Conscious Manufacturing Integrated Demonstration was to show that several of the individually developed materials and processes to reduce hazardous materials and waste could be successfully used on a single assembly. A methodology was developed that could be used on any product to plan the approach to eliminating hazardous materials. Sample units of an existing design electronic unit were fabricated applying this methodology and substituting nonhazardous materials and processes. The results of this project show that total waste can be drastically reduced by at least an order of magnitude and hazardous material and waste can be essentially eliminated in the manufacture of this type of electronic devices.

  1. IES Integrated Learning Assessment Final Report. CRESST Report 788

    Science.gov (United States)

    Silver, David; Hansen, Mark; Herman, Joan; Silk, Yael; Greenleaf, Cynthia L.

    2011-01-01

    The main purpose of this study was to examine the effects of the Reading Apprenticeship professional development program on several teacher and student outcomes, including effects on student learning. A key part of the study was the use of an enhanced performance assessment program, the Integrated Learning Assessment (ILA), to measure student…

  2. Buried Waste Integrated Demonstration Technology Preparedness and Status Report Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Blacker, P.B.; Bonnenberg, R.W.; Cannon, P.G.; Hyde, R.A.; Watson, L.R.

    1994-04-01

    A Technology Preparedness and Status Report is required for each Technical Task Plan funded by the Buried Waste Integrated Demonstration. This document provides guidance for the preparation of that report. Major sections of the report will include a subset of the need for the technology, objectives of the demonstration, technology description and readiness evaluation, demonstration requirements, and preparedness checklist and action plan.

  3. COMPROMISE EFFECT ON CONSUMERS’ BEHAVIOR

    Directory of Open Access Journals (Sweden)

    Markus Surkamta Eric Santosa

    2016-09-01

    Full Text Available The way consumers think about the products they will buy determines their buying behavior. The decision to buy a particular product is obviously in accordance with the buyer’s attitude. The buyers will also feel more comfortable if their behavior meets with the approval and expectations of the people close to them. While the development of a certain attitude has no effect on subjective judgment, the effect of compromise is likely to make a contribution to its development. Since it is still unclear, this study’s main purposed is to clarify this. In addition, while an attitude is theorized as being a predictor of behavior, through behavioral intention, the study’s secondary purpose is to boost the earlier findings. Likewise, in accordance with the theory of planned behavior, the study will also examine the other predictors of behavioral intention, in relation to the behavioral intention itself. A sample consisting of a 100 respondents was compiled by using the convenience and judgment technique. The data were analyzed using Amos 16.0 and SPSS 16.0. As expected, the compromise effect had a significant influence on whether the customers’ attitude or the subjective norm was the main determinant. Likewise, the customers’ attitude, the subjective norm and perceived behavioral control were confirmed as good predictors of customers’ behavioral intentions.

  4. ClearFuels-Rentech Integrated Biorefinery Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Pearson, Joshua [Project Director

    2014-02-26

    The project Final Report describes the validation of the performance of the integration of two technologies that were proven individually on a pilot scale and were demonstrated as a pilot scale integrated biorefinery. The integrated technologies were a larger scale ClearFuels’ (CF) advanced flexible biomass to syngas thermochemical high efficiency hydrothermal reformer (HEHTR) technology with Rentech’s (RTK) existing synthetic gas to liquids (GTL) technology.

  5. THE MANAGEMENT ACCOUNTING TOOLS AND THE INTEGRATED REPORTING

    Directory of Open Access Journals (Sweden)

    Gabriel JINGA

    2015-04-01

    Full Text Available During the recent years the stakeholders are asking for other pieces of information to be published along with the financial one, such as risk reporting, intangibles, social and environmental accounting. The type of corporate reporting which incorporates the elements enumerated above is the integrated reporting. In this article, we argue that the information disclosed in the integrated reports is prepared by the management accounting, not only by the financial accounting. Thus, we search for the management accounting tools which are used by the companies which prepare integrated reports. In order to do this, we analytically reviewed all the reports available on the website of a selected company. Our results show that the company is using most of the management accounting tools mentioned in the literature review part.

  6. [FY 2014 progress report]: Integrated Waterbird Management and Monitoring

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This progress report for Integrated Waterbird Management and Monitoring covers activities during FY2014. Working with partners across the regions, this landscape...

  7. Community for Data Integration 2015 annual report

    Science.gov (United States)

    Langseth, Madison L.; Chang, Michelle Y.; Carlino, Jennifer; Bellmore, J. Ryan; Birch, Daniella D.; Bradley, Joshua; Bristol, R. Sky; Buscombe, Daniel D.; Duda, Jeffrey J.; Everette, Anthony L.; Graves, Tabitha A.; Greenwood, Michelle M.; Govoni, David L.; Henkel, Heather S.; Hutchison, Vivian B.; Jones, Brenda K.; Kern, Tim; Lacey, Jennifer; Lamb, Rynn M.; Lightsom, Frances L.; Long, John L.; Saleh, Ra'ad A.; Smith, Stan W.; Soulard, Christopher E.; Viger, Roland J.; Warrick, Jonathan A.; Wesenberg, Katherine E.; Wieferich, Daniel J.; Winslow, Luke A.

    2016-10-28

    The Community for Data Integration (CDI) continued to experience success in fiscal year 2015. The CDI community members have been sharing, learning, and collaborating through monthly forums, workshops, working groups, and funded projects. In fiscal year 2015, CDI coordinated 10 monthly forums with 16 different speakers from the U.S. Geological Survey and external partners; funded 11 collaborative projects; and hosted an in-person, four-day workshop, which attracted 168 (134 in-person and 34 remote) data practitioners, data providers, and data consumers from across the USGS, academia, industry, and other government agencies. The Citizen Science, Connected Devices, Data Management, Semantic Web, and Tech Stack Working Groups continued to accomplish great things in fiscal year 2015. These working groups were major stakeholders in planning the 2015 CDI Workshop; they continued developing solutions to pressing challenges, and they brought in speakers throughout the year for more focused presentations and discussions. Additionally, a new working group formed during the 2015 CDI Workshop—the Earth-Science Themes Working Group.

  8. Fluorescent reporters for markerless genomic integration in Staphylococcus aureus

    Science.gov (United States)

    de Jong, Nienke W. M.; van der Horst, Thijs; van Strijp, Jos A. G.; Nijland, Reindert

    2017-01-01

    We present integration vectors for Staphylococcus aureus encoding the fluorescent reporters mAmetrine, CFP, sGFP, YFP, mCherry and mKate. The expression is driven either from the sarA-P1 promoter or from any other promoter of choice. The reporter can be inserted markerless in the chromosome of a wide range of S. aureus strains. The integration site chosen does not disrupt any open reading frame, provides good expression, and has no detectable effect on the strains physiology. As an intermediate construct, we present a set of replicating plasmids containing the same fluorescent reporters. Also in these reporter plasmids the sarA-P1 promoter can be replaced by any other promoter of interest for expression studies. Cassettes from the replication plasmids can be readily swapped with the integration vector. With these constructs it becomes possible to monitor reporters of separate fluorescent wavelengths simultaneously. PMID:28266573

  9. GOVERNMENTAL FINANCIAL REPORTS: BETWEEN VARIETY AND INTEGRATION

    Directory of Open Access Journals (Sweden)

    Andrei R. CRIŞAN

    2014-06-01

    Full Text Available Governments in general provide two main types of financial information: Government Finance Statistics (GFS, used for macroeconomic analysis and General Purpose Financial Reports (GPFR, more or less according with International Public Sector Accounting Standards, used for making decisions in the public sector entities. The aim of this paper is to make a comparison between GFS and GPFR to extract the similarities and differences between them. The documents of GFS and GPFS will be compared row by row, relieving the common and the different components. Our proposal is to create a unique informational system which generates both GFS and GPFS. This system could bring significant benefits such as saving time or reducing costs.

  10. Integrative Report on a culture-sensitive quality & curriculum framework

    NARCIS (Netherlands)

    Sylva, Kathy; Ereky-Stevens, Katharina; Pastori, Giulia; Slot, P.L.; Lerkkanen, Marja-Kristiina

    2016-01-01

    This report draws together research findings that support a comprehensive culture-sensitive European curriculum and quality assessment framework that can inform practice, teacher education and policy. The aim of this integrative report is to inform the development of a comprehensive, culture-sensiti

  11. The integrated reporting: A presentation of the current state of art and aspects of integrated reporting that need further development

    Directory of Open Access Journals (Sweden)

    Jordi Morros

    2016-02-01

    Full Text Available Purpose: The purpose of this paper is to synthesise what is the emerging field of integrated reporting, with particular emphasis in the International Integrated Reporting Council, and outline a list of items for future research in this area. Design/methodology/approach: The approach is to outline a presentation of integrated reporting (IR, and make a review of the implications for the research agenda of the most important items. Findings: The need for quality researchers to address a number of pressing challenges posed by the rapid development of IR policies and practices. Research limitations/implications: The paper provide insights into issues and aspects of integrated reporting that need further development and need robust evidence to help inform improvements in policy and practice. Practical implications: Highlight how companies may benefit from integrated reporting in response to stakeholders’ calls for enhanced disclosure of environmental, social, governance and other non financial information. Social implications: The main social implication is to promote the wider public interest of improving the relevance of information for decision-making, for all stakeholders, and allow greater efficiency in the allocation of financial and other resources and in adding public value Originality/value: This paper offers a general view on a subject that is a challenge for entities oriented to the implementation of sustainability in their values and also in their reporting.

  12. 241-AY Double Shell Tanks (DST) Integrity Assessment Report

    Energy Technology Data Exchange (ETDEWEB)

    JENSEN, C.E.

    1999-09-21

    This report presents the results of the integrity assessment of the 241-AY double-shell tank farm facility located in the 200 East Area of the Hanford Site. The assessment included the design evaluation and integrity examinations of the tanks and concluded that the facility is adequately designed, is compatible with the waste, and is fit for use. Recommendations including subsequent examinations. are made to ensure the continued safe operation of the tanks.

  13. 241-AZ Double Shell Tanks (DST) Integrity Assessment Report

    Energy Technology Data Exchange (ETDEWEB)

    JENSEN, C.E.

    1999-09-21

    This report presents the results of the integrity assessment of the 241-A2 double-shell tank farm facility located in the 200 East Area of the Hanford Site. The assessment included the design evaluation and integrity examinations of the tanks and concluded that the facility is adequately designed, is compatible with the waste, and is fit for use. Recommendations including subsequent examinations, are made to ensure the continued safe operation of the tanks.

  14. KEY PERFORMANCE INDICATORS DISCLOSURES BY THE INTEGRATED REPORTING

    Directory of Open Access Journals (Sweden)

    BOBITAN ROXANA-IOANA

    2016-02-01

    Full Text Available We are in a new era of corporate reporting where the corporate reporting landscape was changed. Institutional and small investors, financial analysts and other key stakeholders are demanding more information about long-term strategies and profitability of companies. Also, the increasing complexity of business models, growing awareness of climate change and resource scarcity and communication are expectations of the role of business in the 21st century and which the key of performance indicators (KPIs is. The companies must change the way these KPIs are being incorporated throughout the annual report and how these are linked to the company’s strategy and business model, their risks and risk mitigation, and their incentive schemes. Regarding this, integrated reporting, continue to gain momentum, the spotlight on the depth, breadth and quality of KPIs being reported will only strengthen. The aim of this discussion paper is to describe which are the most important key performance indicators in sprit of integrating reporting. A good and very known example for the integrated reporting is Philips Electronics, the Dutch healthcare and lighting company, a pioneer that embrace this concept, and the paper make an analysis of the most important key performance indicators.

  15. Analysis of Waste Isolation Pilot Plant Samples: Integrated Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Britt, Phillip F [ORNL

    2015-03-01

    Analysis of Waste Isolation Pilot Plant Samples: Integrated Summary Report. Summaries of conclusions, analytical processes, and analytical results. Analysis of samples taken from the Waste Isolation Pilot Plant (WIPP) near Carlsbad, New Mexico in support of the WIPP Technical Assessment Team (TAT) activities to determine to the extent feasible the mechanisms and chemical reactions that may have resulted in the breach of at least one waste drum and release of waste material in WIPP Panel 7 Room 7 on February 14, 2014. This report integrates and summarizes the results contained in three separate reports, described below, and draws conclusions based on those results. Chemical and Radiochemical Analyses of WIPP Samples R-15 C5 SWB and R16 C-4 Lip; PNNL-24003, Pacific Northwest National Laboratory, December 2014 Analysis of Waste Isolation Pilot Plant (WIPP) Underground and MgO Samples by the Savannah River National Laboratory (SRNL); SRNL-STI-2014-00617; Savannah River National Laboratory, December 2014 Report for WIPP UG Sample #3, R15C5 (9/3/14); LLNL-TR-667015; Lawrence Livermore National Laboratory, January 2015 This report is also contained in the Waste Isolation Pilot Plant Technical Assessment Team Report; SRNL-RP-2015-01198; Savannah River National Laboratory, March 17, 2015, as Appendix C: Analysis Integrated Summary Report.

  16. Integrated Disposal Facility FY 2012 Glass Testing Summary Report, Erratum

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Gary L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-09-02

    Erratum This report refers to or contains Kg values for glasses LAWA44, LAWB45 and LAWC22 affected by calculations errors as identified by Papathanassiu et al. (2011) The corrected Kg values are reported in an erratum included in the revised version of the original report. The revised report can be referenced as follows: Pierce E. M. et al. (2004) Waste Form Release Data Package for the 2005 Integrated Disposal Facility Performance Assessment. PNNL-14805 Rev. 0 Erratum. Pacific Northwest National Laboratory, Richland, WA, USA.

  17. Integrated Disposal Facility FY2011 Glass Testing Summary Report Erratum

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Gary L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-09-06

    This report refers to or contains Kg values for glasses LAWA44, LAWB45 and LAWC22 affected by calculations errors as identified by Papathanassiu et al. (2011). The corrected Kg values are reported in an erratum included in the revised version of the original report. The revised report can be referenced as follows: Pierce E. M. et al. (2004) Waste Form Release Data Package for the 2005 Integrated Disposal Facility Performance Assessment. PNNL-14805 Rev. 0 Erratum. Pacific Northwest National Laboratory, Richland, WA, USA.

  18. [Integrating information about imaging biomarkers into structured radiology reports].

    Science.gov (United States)

    Pomar-Nadal, A; Pérez-Castillo, C; Alberich-Bayarri, A; García-Martí, G; Sanz Requena, R; Martí-Bonmatí, L

    2013-01-01

    Imaging biomarkers describe objective characteristics that are related to normal biological processes, diseases, or the response to treatment. They enable radiologists to incorporate into their reports data about structure, function, and tissue components. With the aim of taking maximum advantage of the quantification of medical images, we present a procedure to integrate imaging biomarkers into radiological reports, bringing the new paradigm of personal medicine closer to radiological workflow. In this manner, the results of quantification can complement traditional radiological diagnosis, improving accuracy and the evaluation of the efficacy of treatments. A more personalized, standardized, structured radiological report should include quantitative analyses to complement conventional qualitative reporting in selected cases.

  19. Integrated Disposal Facility FY 2012 Glass Testing Summary Report, Erratum

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Gary L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-09-02

    This report refers to or contains Kg values for glasses LAWA44, LAWB45 and LAWC22 affected by calculations errors as identified by Papathanassiu et al. (2011) The corrected Kg values are reported in an erratum included in the revised version of the original report. The revised report can be referenced as follows: Pierce E. M. et al. (2004) Waste Form Release Data Package for the 2005 Integrated Disposal Facility Performance Assessment. PNNL-14805 Rev. 0 Erratum. Pacific Northwest National Laboratory, Richland, WA, USA.

  20. Integrated Disposal Facility FY2011 Glass Testing Summary Report. Erratum

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Gary L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-09-06

    This report refers to or contains Kg values for glasses LAWA44, LAWB45 and LAWC22 affected by calculations errors as identified by Papathanassiu et al. (2011). The corrected Kg values are reported in an erratum included in the revised version of the original report. The revised report can be referenced as follows: Pierce E. M. et al. (2004) Waste Form Release Data Package for the 2005 Integrated Disposal Facility Performance Assessment. PNNL-14805 Rev. 0 Erratum. Pacific Northwest National Laboratory, Richland, WA, USA.

  1. Integral Fast Reactor Program annual progress report, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  2. Integral Fast Reactor Program annual progress report, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R D.

  3. Hawaii Integrated Biofuels Research Program: Final Subcontract Report, Phase III

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    This report is a compilation of studies done to develop an integrated set of strategies for the production of energy from renewable resources in Hawaii. Because of the close coordination between this program and other ongoing DOE research, the work will have broad-based applicability to the entire United States.

  4. Integrated Safety and Environment Group Annual Report 2003

    CERN Document Server

    Bóna, M; Segura-Millan, G; Castoldi, M; Kerhoas, A

    2004-01-01

    This report summarizes the main activities of the Integrated Safety and Environment (IE) Group of the Safety Commission (TIS) during the year 2003, and the results obtained. The different topics in which the group is active are covered: environment, quality management, safety training and major accidents follow-up.

  5. Integral Fast Reactor Program annual progress report, FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, J.J.

    1994-12-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1994. Technical accomplishments are presented in the following areas of the IFR technology development activities: metal fuel performance; pyroprocess development; safety experiments and analyses; core design development; fuel cycle demonstration; and LMR technology R&D.

  6. Technical Evaluation Report 29: Integrated Learning Management Systems

    Directory of Open Access Journals (Sweden)

    Linda Schwartz

    2004-04-01

    Full Text Available Four integrated learning management packages were reviewed: CentraOne, IntraLearn, Lyceum, and Silicon Chalk. These products provide different combinations of synchronous and asynchronous tools. The current report examines the products in relation to their specific value for distance educators and students.

  7. Integral Fast Reactor Program. Annual progress report, FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

    1993-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1992. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  8. Integral Fast Reactor Program. Annual progress report, FY 1993

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

    1994-10-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1993. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R and D.

  9. Environmetal report 2016. Impulses for an integrative environmental policy; Umweltgutachten 2016. Impulse fuer eine integrative Umweltpolitik

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-08-01

    The ecological challenges in the EU and Germany are so large that they can no longer simply be addressed using the remedial and even the technically-oriented, preventive environmental protection measures of the past. In relation to climate protection and many other fields, impacts on natural ecosystems must be substantially reduced in order to ensure that key ecosystem services remain functional. Yet, environmental policies continue to encounter stiff opposition, which is targeted at supposedly unnecessary regulatory burdens and restrictions. Opponents of environmental protection claim that environmental policies jeopardize the competitiveness of the German industrial and agricultural sectors by imposing unduly high costs. Or they bring up social issues, such as the current housing crisis or energy poverty, as arguments against an effective environmental policy. Such arguments call for nuanced assessments - and in some cases should be clearly rejected. Defusing such conflicts calls for approaches that promote compromise and that appeal to the general public. In the Environmental Report 2016, the German Advisory Council on the Environment (SRU) sets itself the task of addressing this challenge, by focusing on six key topics. What these topics all have in common is that they exhibit tensions between environmental and economic or social policy goals. The Environmental Report aims to stimulate ideas about environmental oriented reforms and approaches to managing these issues which cut across policy fields.

  10. 26 CFR 301.7122-1 - Compromises.

    Science.gov (United States)

    2010-04-01

    ... for taxes, interest, or penalties. Unless the terms of the offer and acceptance expressly provide otherwise, acceptance of an offer to compromise a civil liability does not remit a criminal liability, nor does acceptance of an offer to compromise a criminal liability remit a civil liability. (b) Grounds...

  11. THE INTEGRATED REPORTING FRAMEWORK: BETWEEN CHALLENGE AND INNOVATION

    Directory of Open Access Journals (Sweden)

    Tudor OPRIȘOR

    2014-06-01

    Full Text Available Integrated Reporting has lately shown a great amount of interest for the business community, as it can offer a greater information value to all types of users. Thus, creating a proper framework for this type of reporting has been a top priority for the regulating bodies, with significant input from other interested parties. This paper aims to analyze the comments submitted to the Consultation Draft and to determine which questions gained more focus. Moreover, through this paper, we intend to reveal which types of respondents were more interested in discussing the Framework and to split them into several groups of interest. Finally, the main goal of the paper is to provide an overview on the discussions leading to the Framework’s final form and to determine how the comment letters can provide further perspectives on the implementation of Integrated Reporting.

  12. THE VALUE OF INTEGRITY IN THE REPORTS OF WORK

    Directory of Open Access Journals (Sweden)

    Simona-Roxana ULMAN

    2015-03-01

    Full Text Available The most important aim of this paper is to identify the main general ethical values conducting to personal integrity, to build the general ethical values pyramid and, so, helping to improve the reports of labor for having positive results on the economic field. In this context, the human psychological development theory thorough by Maslow is exploited as example for the building of a human values hierarchy necessary to the individual as a social being to engage in normal interactions with the others. These general values are an imperative for the person’s integration in society, also contributing to his belonging society’s welfare and to its performance.

  13. Oiling the wheels of compromise

    DEFF Research Database (Denmark)

    Beach, Derek

    2006-01-01

    The EU’s Council Secretariat plays a very important but overlooked role in helping EU governments reform EU Treaties, but the dependence of governments on the Secretariat has ‘costs’, in that outcomes are systematically skewed towards the rational-legalistic and pro-integrative/pro-Council prefer......The EU’s Council Secretariat plays a very important but overlooked role in helping EU governments reform EU Treaties, but the dependence of governments on the Secretariat has ‘costs’, in that outcomes are systematically skewed towards the rational-legalistic and pro......-integrative/pro-Council preferences of the Secretariat. The paper first develops a theory for why governments delegate leadership functions to the Secretariat, and what effects this delegation can have. Thereafter the paper undertakes a comparative case study of two rounds of EU Treaty reform; the negotiation of the Treaty...... of Amsterdam in 1996-97, and the Constitutional Treaty in 2003-4. It is found that the Secretariat was more than a mere facilitator of agreement, and that leadership by the Secretariat had a significant impact upon the form of the final Treaties....

  14. Orthodontic management of a periodontally compromised dentition

    Directory of Open Access Journals (Sweden)

    Prashant K Zaveri

    2016-01-01

    Full Text Available Malocclusion superimposed with severe periodontitis may present a great challenge to clinicians while providing orthodontic treatment due the episodic and site-specific nature of the disease with risk of rapid tissue breakdown. However, orthodontic treatment in such situation may contribute significantly to the overall rehabilitation both functionally and esthetically. In this article, a case report outlines a combined periodontic-orthodontic management of compromised dentition. A 37-year-old female patient with significant medical history was treated for Class II Division 1 type of malocclusion associated with spaced upper and lower anterior teeth, deep overbite, and increased overjet, superimposed with chronic generalized periodontitis and bone loss. Treatment was completed using temporary anchorage devices assisted strategically applied force and modified tandem retraction biomechanics amidst management of acute inflammatory episodes during and mucogingival complication after treatment. Affected areas healed very well after post-orthodontic periodontal treatment with minimal pocket depth, and bleeding on probing, and a healthy zone of attached gingiva at the follow up visits. The orthodontic results lead to improvement in patient's facial profile, lip posture, and correction of protrusion which addressed her main concern. One year follow-up shows good orthodontic and periodontic stability. The report highlights the importance of identifying “at risk” individuals and continuous monitoring of disease status during treatment. Despite all precautionary measures, a flare-up during the treatment can be anticipated.

  15. INTEGRATED REPORTING INTO PRACTICE – A TEN YEAR EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Mihaela TURTUREA

    2015-04-01

    Full Text Available Nowadays business environment can be described through continuous changes, complexity, raising concerns regarding the limited non-renewable resources. Through changes in the reporting practice and by demonstrating a great commitment to responsible corporate day-to-day activities, companies are able to increase their performances on the market. This research aims to underline the performance achieved by “one of the earlier adopters” of integrated reporting by correlating financial performance indicators to its stock price evolution. The results show that responsible actions directed towards social and environmental causes demonstrate a more visible, transparent and active side of a business which helps companies in achieving higher performances.

  16. The social-financial responsible reporting – the key for integrated reporting

    Directory of Open Access Journals (Sweden)

    Iulia Jianu

    2012-08-01

    Full Text Available General purpose of financial statements is to satisfy the needs of users who are not in the position to require of the entity to prepare reports tailored to their particular information needs. Because the public is one of these users interested of social information and because the financial statement do not provide sufficient social information to satisfy these needs, the study demonstrate the need to integrate the responsible social reporting into financial reporting. In order to support this reason, taking into account the data supplied by the entities listed on the Global Reporting Initiative regarding the corporate social responsibility. The results of the study show that social indicators can be disclosed in a monetary form which reinforces the need for their integration into financial reporting and the need to define a new concept: the social – financial responsible reporting.

  17. Obesity May Not Compromise Knee Surgery Success

    Science.gov (United States)

    ... 164282.html Obesity May Not Compromise Knee Surgery Success Results similar after procedure to repair meniscus in ... the surgery and they would have the same success as someone who is not as heavy," he ...

  18. The Social-Financial Responsible Reporting – The Key for Integrated Reporting

    OpenAIRE

    Iulia Jianu

    2012-01-01

    General purpose of financial statements is to satisfy the needs of users who are not in the position to require of the entity to prepare reports tailored to their particular information needs. Because the public is one of these users interested of social information and because the financial statement do not provide sufficient social information to satisfy these needs, the study demonstrate the need to integrate the responsible social reporting into financial reporting. In order to support th...

  19. Great Basin Integrated Landscape Monitoring Pilot Summary Report

    Science.gov (United States)

    Finn, Sean P.; Kitchell, Kate; Baer, Lori Anne; Bedford, David R.; Brooks, Matthew L.; Flint, Alan L.; Flint, Lorraine E.; Matchett, J.R.; Mathie, Amy; Miller, David M.; Pilliod, David S.; Torregrosa, Alicia; Woodward, Andrea

    2010-01-01

    The Great Basin Integrated Landscape Monitoring Pilot project (GBILM) was one of four regional pilots to implement the U.S. Geological Survey (USGS) Science Thrust on Integrated Landscape Monitoring (ILM) whose goal was to observe, understand, and predict landscape change and its implications on natural resources at multiple spatial and temporal scales and address priority natural resource management and policy issues. The Great Basin is undergoing rapid environmental change stemming from interactions among global climate trends, increasing human populations, expanding and accelerating land and water uses, invasive species, and altered fire regimes. GBLIM tested concepts and developed tools to store and analyze monitoring data, understand change at multiple scales, and forecast landscape change. The GBILM endeavored to develop and test a landscape-level monitoring approach in the Great Basin that integrates USGS disciplines, addresses priority management questions, catalogs and uses existing monitoring data, evaluates change at multiple scales, and contributes to development of regional monitoring strategies. GBILM functioned as an integrative team from 2005 to 2010, producing more than 35 science and data management products that addressed pressing ecosystem drivers and resource management agency needs in the region. This report summarizes the approaches and methods of this interdisciplinary effort, identifies and describes the products generated, and provides lessons learned during the project.

  20. Short-Termed Integrated Forecasting System: 1993 Model documentation report

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The purpose of this report is to define the Short-Term Integrated Forecasting System (STIFS) and describe its basic properties. The Energy Information Administration (EIA) of the US Energy Department (DOE) developed the STIFS model to generate short-term (up to 8 quarters), monthly forecasts of US supplies, demands, imports exports, stocks, and prices of various forms of energy. The models that constitute STIFS generate forecasts for a wide range of possible scenarios, including the following ones done routinely on a quarterly basis: A base (mid) world oil price and medium economic growth. A low world oil price and high economic growth. A high world oil price and low economic growth. This report is written for persons who want to know how short-term energy markets forecasts are produced by EIA. The report is intended as a reference document for model analysts, users, and the public.

  1. Short-Termed Integrated Forecasting System: 1993 Model documentation report

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The purpose of this report is to define the Short-Term Integrated Forecasting System (STIFS) and describe its basic properties. The Energy Information Administration (EIA) of the US Energy Department (DOE) developed the STIFS model to generate short-term (up to 8 quarters), monthly forecasts of US supplies, demands, imports exports, stocks, and prices of various forms of energy. The models that constitute STIFS generate forecasts for a wide range of possible scenarios, including the following ones done routinely on a quarterly basis: A base (mid) world oil price and medium economic growth. A low world oil price and high economic growth. A high world oil price and low economic growth. This report is written for persons who want to know how short-term energy markets forecasts are produced by EIA. The report is intended as a reference document for model analysts, users, and the public.

  2. Report on Integrating Activities and Models for Collaboration

    DEFF Research Database (Denmark)

    Buus, Lillian; Dirckinck-Holmfeld, Lone; Ryberg, Thomas;

    environments. A part of the focus of the ERT is developing synergies between the partners by strengthening existing relationships, and creating new networks to develop and research into conditions for joint research on conditions for productive learning in networked learning environments and networked learning......This report is the deliverable for work package (WP) 28.3 “Integrated network and activities for the exchange of and collaboration between Master students, PhD students and professors” of the European Research Team (ERT) on Conditions for Productive Networked Learning Environments. The objective...... of WP28.3 is to build up an integrated network and activities for the exchange and collaboration between Master students, professional masters, PhD students and professors and to establish a virtual community around the research area of conditions for productive learning in networked learning...

  3. Physics of vertically integrated waveguide photodetectors and amplifiers. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Wright, E.M. [Univ. of Arizona, Tucson, AZ (United States). Optical Sciences Center

    1993-11-01

    This report describes the efforts supported by LLNL under the Subcontract No. B239593 at the University of Arizona during the Fiscal Year 1992. A solid physical foundation has been developed for understanding the operation of vertically integrated photodetectors and amplifiers. This has been achieved through a combination of numerical simulation and development of simple coupled-mode theories. Coupled-mode theory has been used to elucidate the physics underlying the operation of vertically integrated photodetectors. In particular, the relation between the spatial transients observed in experiments and numerical simulations, and the non-power orthogonality of the underlying modes has been clarified. The coupled-mode theory has been extended to the case of coupled waveguide-amplifiers.

  4. Environmental report 1993: Part 1: Integral report for nitrogen. Milieurapportage 1993: Deel 1: Integrale rapportage stikstof

    Energy Technology Data Exchange (ETDEWEB)

    Aben, J.J.M.; Aldenkamp, F.; Heij, B.J.; Van Liere, L.; Thomas, R.; Verweij, W.; Willems, J. (comps.)

    1994-01-01

    The final aim of the project Environmental Balance/Environmental Outline (MB/MV, abbreviated in Dutch) of the Dutch National Institute of Public Health and Environmental Protection (RIVM) is to publish the Environmental Balance annually and the Environmental Outline every four years. The project is subdivided into three sub-projects: (1) product development: what should be in the MB/MV and how should the contents be structured; (2) the infrastructure: developing, improving, gearing the activities to produce the MB/MV; and (3) pre-production and pilots: practising and testing processes and concepts. The sub-project (3) resulted in three types of products: (a) so-called compartment (air, soil, and water) reports for the air quality, radiation, drinking water, and quality of soil and ground water, (b) integrated reports for nitrogen and ozone/ultraviolet radiation, and (c) an evaluation of the production process. The purpose of the integrated reports was to practise cooperation, coordination and integration within the RIVM, in order to produce MB/MV-reports. In particular, attention has been paid to the flow of information and information models. In this integral report the emissions of nitrogen compounds to the environment and the occurrence of nitrogen compounds in the different environmental compartments are described. Also the effects of those emissions on terrestrial and aquatic ecosystems and on public health are dealt with. 58 figs., 42 tabs., refs.

  5. 2013 strategic petroleum reserve big hill well integrity grading report.

    Energy Technology Data Exchange (ETDEWEB)

    Lord, David L.; Roberts, Barry L.; Lord, Anna C. Snider; Bettin, Giorgia; Sobolik, Steven Ronald; Park, Byoung Yoon; Rudeen, David Keith; Eldredge, Lisa; Wynn, Karen; Checkai, Dean; Perry, James Thomas

    2014-02-01

    This report summarizes the work performed in developing a framework for the prioritization of cavern access wells for remediation and monitoring at the Big Hill Strategic Petroleum Reserve site. This framework was then applied to all 28 wells at the Big Hill site with each well receiving a grade for remediation and monitoring. Numerous factors affecting well integrity were incorporated into the grading framework including casing survey results, cavern pressure history, results from geomechanical simulations, and site geologic factors. The framework was developed in a way as to be applicable to all four of the Strategic Petroleum Reserve sites.

  6. The ethics of moral compromise for stem cell research policy.

    Science.gov (United States)

    Master, Zubin; Crozier, G K D

    2012-03-01

    In the US, stem cell research is at a moral impasse-many see this research as ethically mandated due to its potential for ameliorating major diseases, while others see this research as ethically impermissible because it typically involves the destruction of embryos and use of ova from women. Because their creation does not require embryos or ova, induced pluripotent stem cells offer the most promising path for addressing the main ethical objections to stem cell research; however, this technology is still in development. In order for scientists to advance induced pluripotent stem cell research to a point of translational readiness, they must continue to use ova and embryos in the interim. How then are we to ethically move forward with stem cell research? We argue that there is personal integrity and value in adopting a 'moral compromise' as a means for moving past the moral impasse in stem cell research. In a moral compromise, each party concedes part of their desired outcome in order to engage in a process that respects the values and desires of all parties equitably. Whereas some contend that moral compromise in stem cell research necessarily involves self-contradiction or loss of personal integrity, we argue that in the US context, stem cell research satisfies many of the key pre-conditions of an effective moral compromise. To illustrate our point, we offer a model solution wherein eggs and embryos are temporarily used until non-egg and non-embryonic sources of pluripotent stem cells are developed to a state of translational readiness.

  7. Naturkraft integration at Kaarstoe. Mapping study report 6 march 2009

    Energy Technology Data Exchange (ETDEWEB)

    Odland, Oeystein; Hoeie, Hans; Aanestad, Per; Hauge, Bjoern I.; Solvang, Svein; Boee, Stein Espen; Lervik, Steinar; Kristiansen, Arild

    2007-07-01

    Gassco is engaged in three different studies and projects related to reduce CO{sub 2} emissions at Kaarstoe; 1. Gassnova's CO{sub 2} capture, transport and storage projects at Kaarstoe and Mongstad (the CO{sub 2} Transportation Network), where Gassco role is to mature the transportation facilities of the project. An investment decision is planned for second half of 2009. 2. The Kaarstoe Flue Gas Capture pre-feasibility study initiated by the MPE to Gassco as operator of Gassled in connection with approval of the Kaarstoe Expansion Project 2010, to evaluate the potential of capturing the CO{sub 2} emissions at the Kaarstoe gas processing plant, and reported to the MPE 3 March 2009, and 3. This Naturkraft Integration Mapping Study initiated by MPE to meet the requirements set out by the letter to Gassco dated 3 December 2008 to evaluate possibilities to integrate existing Naturkraft's power plant with the Kaarstoe gas processing plant. In this Naturkraft Integration Study report Gassco has identified potential degrees of integration and resulting impact with respect to performance of both the Naturkraft power plant and the Kaarstoe gas processing plant. A major concern related to operations of the Kaarstoe gas processing plant is the regularity and availability issues related to natural gas and NGL export. The value of the petroleum transported over Kaarstoe on any day exceeds 200 million NOK. In addition also significant oil production will be shut down if the Kaarstoe gas processing plant is not operating. Hence the regularity of energy supply including steam is of utmost importance. The integration between Naturkraft and the gas processing plant is based on supplying energy (i.e. fuel gas, steam, heat and electricity) from Naturkraft's existing power plant, and therefore must be based on predictable and steady operations of the Naturkraft power plant. Naturkraft has only been in operation for a few weeks from the start-up of the power plant 1

  8. Resources from waste : integrated resource management phase 1 study report

    Energy Technology Data Exchange (ETDEWEB)

    Corps, C. [Asset Strategics, Victoria BC (Canada); Salter, S. [Farallon Consultants Ltd., Victoria, BC (Canada); Lucey, P. [Aqua-Tex Scientific Consulting Ltd., Victoria, BC (Canada); O' Riordan, J.

    2008-02-29

    Integrated resource management (IRM) of municipal waste streams and water systems requires a structured analysis of options that consider environmental aspects such as greenhouse gases, carbon taxes and credits. Each option's inputs and outputs are assessed to determine the net highest and best use and value. IRM focuses on resource recovery and extracting maximum value. It considers the overall net impact on the taxpayer and requires the integration of liquid and solid waste streams to maximize values for recovering energy in the form of biofuels, heat, minerals, water and reducing electricity demand. IRM is linked to water management through reuse of treated water for groundwater recharge and to offset potable water use for non-potable purposes such as irrigation, including potential commercial use, which contributes to maintaining or improving the health of watersheds. This report presented a conceptual design for the application of IRM in the province of British Columbia (BC) and analyzed its potential contribution to the provincial climate change agenda. The report discussed traditional waste management, the IRM approach, and resource recovery technology and opportunities. The business case for IRM in BC was also outlined. It was concluded that IRM has the potential to be a viable solution to water, solid and liquid waste management that should be less expensive, result in fewer environmental impacts, and provide greater flexibility than traditional approaches to waste management. 63 refs., 17 tabs., 21 figs., 10 appendices.

  9. Choreographies with Secure Boxes and Compromised Principals

    CERN Document Server

    Carbone, Marco; 10.4204/EPTCS.12.1

    2009-01-01

    We equip choreography-level session descriptions with a simple abstraction of a security infrastructure. Message components may be enclosed within (possibly nested) "boxes" annotated with the intended source and destination of those components. The boxes are to be implemented with cryptography. Strand spaces provide a semantics for these choreographies, in which some roles may be played by compromised principals. A skeleton is a partially ordered structure containing local behaviors (strands) executed by regular (non-compromised) principals. A skeleton is realized if it contains enough regular strands so that it could actually occur, in combination with any possible activity of compromised principals. It is delivery guaranteed (DG) realized if, in addition, every message transmitted to a regular participant is also delivered. We define a novel transition system on skeletons, in which the steps add regular strands. These steps solve tests, i.e. parts of the skeleton that could not occur without additional regu...

  10. Adanced Recovery and Integrated Extraction System (ARIES). Preconceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, T.O.; Bronson, M.C.; Dennison, D.K.; Flamm, B. [and others

    1996-09-01

    This document describes the preliminary conceptual design of the Advanced Recovery and Integrated Extraction System (ARIES). The ARIES is an overall processing system for the dismantlement of nuclear weapon primaries. The program will demonstrate dismantlement of nuclear weapons and retrieval of the plutonium into a form that is compatible with long-term storage and that is inspectable in an unclassified form appropriate for the application of traditional international safeguards. The purpose of the ARIES process is to receive weapon pits, disassemble them, and provide a product of either a plutonium metal button or plutonium oxide powder appropriately canned to meet all requirements for long-term storage. This demonstration is a 24-month program, with full operation planned during the last three-six months to gain confidence in the system`s flexibility and reliability. The ARIES system is modular in design to offer credible scaling and the ability to incorporate modifications or new concepts. This report describes the preconceptual design of each of the ARIES modules, as well as the integration of the overall system.

  11. HyPEP FY-07 Report: System Integration Model Development

    Energy Technology Data Exchange (ETDEWEB)

    C. H. Oh; E. S. Kim; S. R. Sherman; R. Vilim

    2007-04-01

    The integrated system of a Very High Temperature Gas-Cooled Reactor (VHTR) and a High Temperature Steam Electrolysis (HTSE) process is one of systems being investigated by the U.S. Department of Energy and Idaho National Laboratory. This system will produce hydrogen by utilizing a highly efficient VHTR with an outlet temperature of 900 °C and supplying necessary energy and electricity to the HTSE process for electrolysis of high temperature steam. This report includes a description of five configurations including an indirect parallel cycle, an indirect serial cycle, a direct serial cycle, a steam combined cycle, and a reheat cycle. HYSYS simulations were performed for each of these configurations coupled to a HTSE process. Final results are presented along with parametric studies and process optimization.

  12. Integrated thermal treatment systems study. Internal review panel report

    Energy Technology Data Exchange (ETDEWEB)

    Cudahy, J.; Escarda, T.; Gimpel, R. [and others

    1995-04-01

    The U.S. Department of Energy (DOE) Office of Technology Development (OTD) commissioned two studies to evaluate nineteen thermal treatment technologies for treatment of DOE mixed low-level waste. These studies were called the Integrated Thermal Treatment System (ITTS) Phase I and Phase II. With the help of the DOE Office of Environmental Management (EM) Mixed Waste Focus Group, OTD formed an ITTS Internal Review Panel to review and comment on the ITTS studies. This Panel was composed of scientists and engineers from throughout the DOE complex, the U.S. Environmental Protection Agency, the California EPA, and private experts. The Panel met from November 15-18, 1994 to review the ITTS studies and to make recommendations on the most promising thermal treatment systems for DOE mixed low-level wastes and on research and development necessary to prove the performance of the technologies. This report describes the findings and presents the recommendations of the Panel.

  13. Urban Integrated Industrial Cogeneration Systems Analysis. Phase II final report

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    Through the Urban Integrated Industrial Cogeneration Systems Analysis (UIICSA), the City of Chicago embarked upon an ambitious effort to identify the measure the overall industrial cogeneration market in the city and to evaluate in detail the most promising market opportunities. This report discusses the background of the work completed during Phase II of the UIICSA and presents the results of economic feasibility studies conducted for three potential cogeneration sites in Chicago. Phase II focused on the feasibility of cogeneration at the three most promising sites: the Stockyards and Calumet industrial areas, and the Ford City commercial/industrial complex. Each feasibility case study considered the energy load requirements of the existing facilities at the site and the potential for attracting and serving new growth in the area. Alternative fuels and technologies, and ownership and financing options were also incorporated into the case studies. Finally, site specific considerations such as development incentives, zoning and building code restrictions and environmental requirements were investigated.

  14. Developing the Metodology to Form Integrated Reporting of Agroholdings in the Russian Federation

    Directory of Open Access Journals (Sweden)

    N. N. Balashova

    2015-12-01

    Full Text Available The article represents the efficient methodological principles on preparing the integrated reporting, as well as the scheme of the agroholding coherently integrated registration system based on the analysis of the concept and methodology in the field of the integrated reporting; it specifies "growth points" of the methodology development and best practical applications of the concept of uniform reporting on a global scale. The authors propose the developed by them "road map" on the organization process forming the integrated reports, and define the guidelines on improving the process of preparing and quality of the integrated reporting for the medium-term period.

  15. 19 CFR 172.33 - Acceptance of offers in compromise.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Acceptance of offers in compromise. 172.33 Section... OF THE TREASURY (CONTINUED) CLAIMS FOR LIQUIDATED DAMAGES; PENALTIES SECURED BY BONDS Offers in Compromise § 172.33 Acceptance of offers in compromise. An offer in compromise will be considered...

  16. 19 CFR 171.32 - Acceptance of offers in compromise.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Acceptance of offers in compromise. 171.32 Section... OF THE TREASURY (CONTINUED) FINES, PENALTIES, AND FORFEITURES Offers in Compromise § 171.32 Acceptance of offers in compromise. An offer in compromise will be considered accepted only when the...

  17. INEL integrated spent nuclear fuel consolidation task team report

    Energy Technology Data Exchange (ETDEWEB)

    Henry, R.N.; Clark, J.H.; Chipman, N.A. [and others

    1994-09-12

    This document describes a draft plan and schedule to consolidate spent nuclear fuel (SNF) and special nuclear material (SNW) from aging storage facilities throughout the Idaho National Engineering Laboratory (INEL) to the Idaho Chemical Processing Plant (ICPP) in a safe, cost-effective, and expedient manner. A fully integrated and resource-loaded schedule was developed to achieve consolidation as soon as possible. All of the INEL SNF and SNM management task, projects, and related activities from fiscal year 1994 to the end of the consolidation period are logic-tied and integrated with each other. The schedule and plan are presented to initiate discussion of their implementation, which is expected to generate alternate concepts that can be evaluated using the methodology described in this report. Three perturbations to consolidating SNF as soon as possible are also explored. If the schedule is executed as proposed, the new and on-going consolidation activities will require about 6 years to complete and about $25.3M of additional funding. Reduced annual operating costs are expected to recover the additional investment in about 6.4 years. The total consolidation program as proposed will cost about $66.8M and require about 6 years to recover via reduced operating costs from retired SNF/SNM storage facilities. Detailed schedules and cost estimates for the Test Reactor Area Materials Test Reactor canal transfers are included as an example of the level of detail that is typical of the entire schedule (see Appendix D). The remaining work packages for each of the INEL SNF consolidation transfers are summarized in this document. Detailed cost and resource information is available upon request for any of the SNF consolidation transfers.

  18. The adoption of integrated reporting principles by the Romanian companies listed at the Bucharest Stock Exchange

    Directory of Open Access Journals (Sweden)

    Ioana SOFIAN

    2016-12-01

    Full Text Available This paper aims to identify a company with Romanian capital that has potential to implement the integrated reporting principles, with real benefits in attracting investors and/or building an international reputation. To achieve this goal, we performed a study on companies listed at the Bucharest Stock Exchange that operate in different sectors. We analysed the investment opportunity, the reports published currently by the companies and their compliance with the International Integrated Reporting Framework in the view of preparing an integrated report. The case study revealed a high potential for the implementation of integrated reporting within Antibiotice Iași S.A. As compared to all the selected companies, this company’s reporting practices are currently the most similar to the integrated reporting. However, for the other companies, the option to publish an integrated report is viable under certain conditions, particularly in order to build a business card that is internationally recognized and universally comparable.

  19. When data representation compromise data security

    DEFF Research Database (Denmark)

    Simonsen, Eivind Ortind; Dahl, Mads Ronald

    WHEN DATA REPRESENTATION COMPROMISE DATA SECURITY The workflow of transforming data into informative representations makes extensive usage of computers and software. Scientists have a conventional tradition for producing publications that include tables and graphs as data representations....... These representations can be used for multiple purposes such as publications in journals, teaching and conference material. But when created, stored and distributed in a digital form there is a risk of compromising data security. Data beyond the once used specifically to create the representation can be included...... as Object Linking and Embedding (OLE-objects). The OLE-object may “hide” data, in some cases sensitive data, such as data from research or health care information that was in the original data complex. This issue is known and documented but why is it then still a problem leading to data being exposed...

  20. Radiosurgical planning of meningiomas: compromises with conformity.

    Science.gov (United States)

    Rowe, Jeremy G; Walton, Lee; Vaughan, Paul; Malik, Irfan; Radatz, Matthias; Kemeny, Andras

    2004-01-01

    The radiosurgical planning of meningiomas frequently necessitates compromises between irradiating tumour and risking damage to adjacent structures. In selected cases, we resolved this by excluding part of the tumour from the prescription isodose volume. Most of these compromises or 'suboptimal' plans achieved growth control. Growth control could not be related to conformity indices or to various measures of the radiation dose received by the meningioma. Examining recurrences, 75% arose from dura outside the original treatment field. These findings are discussed in terms of dose prescription protocols and the use of conformity indices in planning. The importance of the dural origin of meningiomas is well established in surgical practice, as reflected by Simpson's grades, but may be equally significant in radiosurgical practice.

  1. Objections to the Libertarian Stem Cell Compromise

    Directory of Open Access Journals (Sweden)

    Walter E. Block

    2010-11-01

    Full Text Available In Block (2010 I offered a compromise between the pro choice position that fervently supports stem cell research, and the pro life philosophy which bitterly opposes it. The compromise was a contest: allow would be researchers to create as many fertilized eggs as they wished. But, also, these should be offered up to would be parents to adopt all of these “children” as they wanted. If and only if there were any unadopted fetuses remaining in the laboratories of the nation would it be licit, on libertarian grounds, for research on them to take place. In the present paper I respond to several objections to this “modest proposal.”

  2. Is conceptual understanding compromised by a problem-solving emphasis in an introductory physics course?

    Science.gov (United States)

    Ridenour, J.; Feldman, G.; Teodorescu, R.; Medsker, L.; Benmouna, N.

    2013-01-01

    Developing competency in problem solving and enhancing conceptual understanding are primary objectives in introductory physics, and many techniques and tools are available to help instructors achieve them. Pedagogically, we use an easy-to-implement intervention, the ACCESS protocol, to develop and assess problem-solving skills in our SCALE-UP classroom environment for algebra-based physics. Based on our research and teaching experience, an important question has emerged: while primarily targeting improvements in problem-solving and cognitive development, is it necessary that conceptual understanding be compromised? To address this question, we gathered and analyzed information about student abilities, backgrounds, and instructional preferences. We report on our progress and give insights into matching the instructional tools to student profiles in order to achieve optimal learning in group-based active learning. The ultimate goal of our work is to integrate individual student learning needs into a pedagogy that moves students closer to expert-like status in problem solving.

  3. Integrated Disposal Facility FY2011 Glass Testing Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, Eric M.; Bacon, Diana H.; Kerisit, Sebastien N.; Windisch, Charles F.; Cantrell, Kirk J.; Valenta, Michelle M.; Burton, Sarah D.; Westsik, Joseph H.

    2011-09-29

    Pacific Northwest National Laboratory was contracted by Washington River Protection Solutions, LLC to provide the technical basis for estimating radionuclide release from the engineered portion of the disposal facility (e.g., source term). Vitrifying the low-activity waste at Hanford is expected to generate over 1.6 x 10{sup 5} m{sup 3} of glass (Certa and Wells 2010). The volume of immobilized low-activity waste (ILAW) at Hanford is the largest in the DOE complex and is one of the largest inventories (approximately 8.9 x 10{sup 14} Bq total activity) of long-lived radionuclides, principally {sup 99}Tc (t{sub 1/2} = 2.1 x 10{sup 5}), planned for disposal in a low-level waste (LLW) facility. Before the ILAW can be disposed, DOE must conduct a performance assessment (PA) for the Integrated Disposal Facility (IDF) that describes the long-term impacts of the disposal facility on public health and environmental resources. As part of the ILAW glass testing program PNNL is implementing a strategy, consisting of experimentation and modeling, in order to provide the technical basis for estimating radionuclide release from the glass waste form in support of future IDF PAs. The purpose of this report is to summarize the progress made in fiscal year (FY) 2011 toward implementing the strategy with the goal of developing an understanding of the long-term corrosion behavior of low-activity waste glasses.

  4. Integrated Disposal Facility FY 2012 Glass Testing Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, Eric M.; Kerisit, Sebastien N.; Krogstad, Eirik J.; Burton, Sarah D.; Bjornstad, Bruce N.; Freedman, Vicky L.; Cantrell, Kirk J.; Snyder, Michelle MV; Crum, Jarrod V.; Westsik, Joseph H.

    2013-03-29

    PNNL is conducting work to provide the technical basis for estimating radionuclide release from the engineered portion of the disposal facility for Hanford immobilized low-activity waste (ILAW). Before the ILAW can be disposed, DOE must conduct a performance assessment (PA) for the Integrated Disposal Facility (IDF) that describes the long-term impacts of the disposal facility on public health and environmental resources. As part of the ILAW glass testing program, PNNL is implementing a strategy, consisting of experimentation and modeling, to provide the technical basis for estimating radionuclide release from the glass waste form in support of future IDF PAs. Key activities in FY12 include upgrading the STOMP/eSTOMP codes to do near-field modeling, geochemical modeling of PCT tests to determine the reaction network to be used in the STOMP codes, conducting PUF tests on selected glasses to simulate and accelerate glass weathering, developing a Monte Carlo simulation tool to predict the characteristics of the weathered glass reaction layer as a function of glass composition, and characterizing glasses and soil samples exhumed from an 8-year lysimeter test. The purpose of this report is to summarize the progress made in fiscal year (FY) 2012 and the first quarter of FY 2013 toward implementing the strategy with the goal of developing an understanding of the long-term corrosion behavior of LAW glasses.

  5. Heat-pump-centered integrated community energy systems. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1979-11-01

    Heat-pump-centered integrated community energy systems (HP-ICES) are energy systems for communities which provide heating, cooling and/or other thermal energy services through the use of heat pumps. Since heat pumps primarily transfer energy from existing and otherwise probably unused sources, rather than convert it from electrical or chemical to thermal form, HP-ICES offer significant potential for energy savings. Secondary benefits of HP-ICES include reduction of adverse environmental effects as compared to conventional systems, reliable production of services in contrast to the increasingly frequent utility curtailments and interruptions, and delivery of services to consumers at costs lower than those for conventional systems (including acquisition, operation, and maintenance costs). The objective of this multiphase project is development and demonstration of HP-ICES concepts leading to one or more operational systems by the end of 1984. The results of the system development phase of the HP-ICES Project are reported. Information is presented on: central heat pump and distributed heat pump ICES; potential applications; waste heat availability; system performance and economics; environmental impacts; site requirements; component testing requirements; mathematical analysis of heat balance and cost relations; and performance and economic analyses of HP-ICES located near Seattle, Washington and San Antonio, Texas. (LCL)

  6. MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

    Directory of Open Access Journals (Sweden)

    Yves Dondelinger

    2014-05-01

    Full Text Available Although mixed lineage kinase domain-like (MLKL protein has emerged as a specific and crucial protein for necroptosis induction, how MLKL transduces the death signal remains poorly understood. Here, we demonstrate that the full four-helical bundle domain (4HBD in the N-terminal region of MLKL is required and sufficient to induce its oligomerization and trigger cell death. Moreover, we found that a patch of positively charged amino acids on the surface of the 4HBD binds to phosphatidylinositol phosphates (PIPs and allows recruitment of MLKL to the plasma membrane. Importantly, we found that recombinant MLKL, but not a mutant lacking these positive charges, induces leakage of PIP-containing liposomes as potently as BAX, supporting a model in which MLKL induces necroptosis by directly permeabilizing the plasma membrane. Accordingly, we found that inhibiting the formation of PI(5P and PI(4,5P2 specifically inhibits tumor necrosis factor (TNF-mediated necroptosis but not apoptosis.

  7. Compromised genomic integrity impedes muscle growth after Atrx inactivation

    OpenAIRE

    Huh, Michael S.; Price O’Dea, Tina; Ouazia, Dahmane; Bruce C McKay; Parise, Gianni; Robin J Parks; Rudnicki, Michael A.; Picketts, David J.

    2012-01-01

    ATR-X syndrome is a severe intellectual disability disorder caused by mutations in the ATRX gene. Many ancillary clinical features are attributed to CNS deficiencies, yet most patients have muscle hypotonia, delayed ambulation, or kyphosis, pointing to an underlying skeletal muscle defect. Here, we identified a cell-intrinsic requirement for Atrx in postnatal muscle growth and regeneration in mice. Mice with skeletal muscle–specific Atrx conditional knockout (Atrx cKO mice) were viable, but b...

  8. Space station operations task force. Panel 4 report: Management integration

    Science.gov (United States)

    1987-01-01

    The Management Integration Panel of the Space Station Operations Task Force was chartered to provide a structure and ground rules for integrating the efforts of the other three panels and to address a number of cross cutting issues that affect all areas of space station operations. Issues addressed include operations concept implementation, alternatives development and integration process, strategic policy issues and options, and program management emphasis areas.

  9. Strained Compromises? Danish Flexicurity During Crisis

    Directory of Open Access Journals (Sweden)

    Christian Lyhne Ibsen

    2011-01-01

    Full Text Available The Danish concept of flexicurity in a `Golden Triangle´ of low job protection, high income security and high employment security is not only about a balance between labor market flexibility and social security. Arguably, it is also a series of more or less stable underlying compromises between social partners about the main mechanisms and aims of labor market regulation which - supposedly - should be focused on employment rather than jobs, and competition on quality rather than on labor costs. However, the `Golden Triangle´ - this article argues - seems in need of complementary concepts. The article therefore introduces, `centralized decentralization´ - a concept that directs our attention to forms of flexibility and security primarily for people in work. Most studies on Danish flexicurity have been carried out under favorable economic conditions. In light of the economic slump hitting Denmark in 2008, this article investigates if and how the recession challenged these compromises by comparing two rounds of case-based interviews in three metalworking companies in 2007 and 2009. It is shown that practice has indeed changed - albeit modestly - due to worsened economic circumstances. For example the case studies show that the hypothesized preference for external numerical flexibility is perhaps too crude as employers use different ways to restructure employment. Especially the examples of de facto concessionary bargaining to save jobs are important here - although the extent of concessions is modest. The evidence thus suggests that the `Golden Triangle´ flexicurity compromises are indeed strained by the economic cycle and that responses to impetus for restructuring are far more nuanced than sometimes portrayed. It is argues that more company studies across national labor markets and industrial relations institutions will enhance our understanding of the dynamics during times of restructuring.

  10. Democracy as a Way to Social Compromise

    Institute of Scientific and Technical Information of China (English)

    Han Zhen

    2006-01-01

    In modem society,democracy as a symbol of social civilization and progress is cherished.Any government or organization,whether truly democratic or not,will claim that it is democratic while its opponents are not.However,as a historical notion,democracy does not possess the quality of absoluteness.In my view,democracy,in its original meaning,should be understood as a way to social compromise,whose aim is to guarantee a relatively fair political life.

  11. Integrated Marketing in Higher Education. Research Report 01-01.

    Science.gov (United States)

    Morris, L. Michelle; Cejda, Brent D.

    Integrated marketing deals with aspects often referred to as the "4 Ps": product, price, place, and promotion. These aspects have also been described as the "4 Cs": customer, cost, convenience, and communication. Integrated marketing has been defined as "a listening-first, database-dependent approach to marketing that includes both a willingness…

  12. Transparent building-integrated PV modules. Phase 1: Comprehensive report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-28

    This Comprehensive Report encompasses the activities that have been undertaken by Kiss + Cathcart, Architects, in conjunction with Energy Photovoltaics, Incorporated (EPV), to develop a flexible patterning system for thin-film photovoltaic (PV) modules for building applications. There are two basic methods for increasing transparency/light transmission by means of patterning the PV film: widening existing scribe lines, or scribing a second series of lines perpendicular to the first. These methods can yield essentially any degree of light transmission, but both result in visible patterns of light and dark on the panel surface. A third proposed method is to burn a grid of dots through the films, independent of the normal cell scribing. This method has the potential to produce a light-transmitting panel with no visible pattern. Ornamental patterns at larger scales can be created using combinations of these techniques. Kiss + Cathcart, Architects, in conjunction with EPV are currently developing a complementary process for the large-scale lamination of thin-film PVs, which enables building integrated (BIPV) modules to be produced in sizes up to 48 in. x 96 in. Flexible laser patterning will be used for three main purposes, all intended to broaden the appeal of the product to the building sector: To create semitransparent thin-film modules for skylights, and in some applications, for vision glazing.; to create patterns for ornamental effects. This application is similar to fritted glass, which is used for shading, visual screening, graphics, and other purposes; and to allow BIPV modules to be fabricated in various sizes and shapes with maximum control over electrical characteristics.

  13. Final Report: RPP-WTP Semi-Integrated Pilot Plant

    Energy Technology Data Exchange (ETDEWEB)

    Duignan, M. R.; Adamson, D. J.; Calloway, T. B.; Fowley, M. D.; Qureshi, Z. H.; Steimke, J. L.; Williams, M. R.; Zamecnik, J. R.

    2005-06-01

    In August 2004 the last of the SIPP task testing ended--a task that formally began with the issuance of the RPP-WTP Test Specification in June 2003. The planning for the task was a major effort in itself and culminated with the input of all stakeholders, DOE, Bechtel National, Inc., Washington Group International, in October 2003 at Hanford, WA (Appendix A). This report documents the activities carried out as a result of that planning. Campaign IV, the fourth and final step towards the Semi-Integrated Pilot Plant (SIPP) task, conducted by the Savannah River National Laboratory (SRNL) at the Savannah River Site, was to take the several recycle streams produced in Campaign III, the third step of the task, and combine them with other simulated recycle and chosen waste streams. (Campaign III was fed recycles from Campaign II, as Campaign II was fed by Campaign I.) The combined stream was processed in a fashion that mimicked the pretreatment operations of the DOE River Protection Project--Waste Treatment and Immobilization Plant (RPP-WTP) with the exception of the Ion Exchange Process. The SIPP task is considered semi-integrated because it only deals with the pretreatment operations of the RPP-WTP. That is, the pilot plant starts by receiving waste from the tank farm and ends when waste is processed to the point of being sent for vitrification. The resulting pretreated LAW and HLW simulants produced by the SIPP were shipped to VSL (Vitreous State Laboratory) and successfully vitrified in pilot WTP melters. Within the SIPP task these steps are referred to as Campaigns and there were four Campaigns in all. Campaign I, which is completely different than other campaigns, subjected a simulant of Hanford Tank 241-AY-102/C-106 (AY102) waste to cross-flow ultrafiltration only and in that process several important recycle streams were produced as a result of washing the simulant and cleaning the cross-flow filter. These streams were fed to subsequent campaigns and that work was

  14. Final Report: RPP-WTP Semi-Integrated Pilot Plant

    Energy Technology Data Exchange (ETDEWEB)

    Duignan, M. R.; Adamson, D. J.; Calloway, T. B.; Fowley, M. D.; Qureshi, Z. H.; Steimke, J. L.; Williams, M. R.; Zamecnik, J. R.

    2005-06-01

    In August 2004 the last of the SIPP task testing ended--a task that formally began with the issuance of the RPP-WTP Test Specification in June 2003. The planning for the task was a major effort in itself and culminated with the input of all stakeholders, DOE, Bechtel National, Inc., Washington Group International, in October 2003 at Hanford, WA (Appendix A). This report documents the activities carried out as a result of that planning. Campaign IV, the fourth and final step towards the Semi-Integrated Pilot Plant (SIPP) task, conducted by the Savannah River National Laboratory (SRNL) at the Savannah River Site, was to take the several recycle streams produced in Campaign III, the third step of the task, and combine them with other simulated recycle and chosen waste streams. (Campaign III was fed recycles from Campaign II, as Campaign II was fed by Campaign I.) The combined stream was processed in a fashion that mimicked the pretreatment operations of the DOE River Protection Project--Waste Treatment and Immobilization Plant (RPP-WTP) with the exception of the Ion Exchange Process. The SIPP task is considered semi-integrated because it only deals with the pretreatment operations of the RPP-WTP. That is, the pilot plant starts by receiving waste from the tank farm and ends when waste is processed to the point of being sent for vitrification. The resulting pretreated LAW and HLW simulants produced by the SIPP were shipped to VSL (Vitreous State Laboratory) and successfully vitrified in pilot WTP melters. Within the SIPP task these steps are referred to as Campaigns and there were four Campaigns in all. Campaign I, which is completely different than other campaigns, subjected a simulant of Hanford Tank 241-AY-102/C-106 (AY102) waste to cross-flow ultrafiltration only and in that process several important recycle streams were produced as a result of washing the simulant and cleaning the cross-flow filter. These streams were fed to subsequent campaigns and that work was

  15. MARKETING COMMUNICATIONS OF VALUE CREATION IN SUSTAINABLE ORGANIZATIONS. THE PRACTICE OF INTEGRATED REPORTS

    National Research Council Canada - National Science Library

    Madalina Dumitru; Raluca Gina Guse; Liliana Feleaga; Dragos Marian Mangiuc; Alexandra Ionelia Feldioreanu

    2015-01-01

      This paper represents an investigation of the communication practices used by the organizations included in the International Integrated Reporting Council's Pilot Programme, in order to investigate...

  16. Statistical Measures of Integrity in Online Testing: Empirical Study

    Science.gov (United States)

    Wielicki, Tom

    2016-01-01

    This paper reports on longitudinal study regarding integrity of testing in an online format as used by e-learning platforms. Specifically, this study explains whether online testing, which implies an open book format is compromising integrity of assessment by encouraging cheating among students. Statistical experiment designed for this study…

  17. Report: integrated industrial waste management systems in China.

    Science.gov (United States)

    Zhang, Wenxin; Roberts, Peter

    2007-06-01

    Various models of urban sustainable development have been introduced in recent years and some of these such as integrated waste management have been proved to be of particular value. Integrated industrial waste management systems include all the administrative, financial, legal, planning and engineering functions involved in solutions to the problems of industrial waste. Even though the pace of the improvement made to China's industrial waste management capacity is impressive, China has been unable to keep up with the increasing demand for waste management. This paper will evaluate the application of integrated industrial waste management systems in promoting urban sustainable development in the context of three case study cities in China (positive case, average case and negative case) by identifying and accessing the factors that affect the success or failure of integrated industrial waste management systems.

  18. Summary Report: U.S.- UK Integration in Helmand

    Science.gov (United States)

    2016-02-01

    understanding of these friction points in their pre-deployment training, and so failed to anticipate some of the challenges they faced in theater . With an...proficiency in select areas For certain areas that are likely to be important in the future, it would be prudent to retain and rehearse integration so that...integration when forces were deployed. Rather, sometimes forces were unfamiliar with each other, were unaware of partner capabilities and methods , and did not

  19. Missouri River Scaphirhynchus albus (pallid sturgeon) effects analysis—Integrative report 2016

    Science.gov (United States)

    Jacobson, Robert B.; Annis, Mandy L.; Colvin, Michael E.; James, Daniel A.; Welker, Timothy L.; Parsley, Michael J.

    2016-07-15

    The Missouri River Pallid Sturgeon Effects Analysis was designed to carry out three components of an assessment of how Missouri River management has affected, and will affect, population dynamics of endangered Scaphirhynchus albus (pallid sturgeon): (1) collection of reliable scientific information, (2) critical assessment and synthesis of available data and analyses, and (3) analysis of the effects of actions on listed species and their habitats. This report is a synthesis of the three components emphasizing development of lines of evidence relating potential future management actions to pallid sturgeon population dynamics. We address 21 working management hypotheses that emerged from an expert opinion-based filtering process.The ability to quantify linkages from abiotic changes to pallid sturgeon population dynamics is compromised by fundamental information gaps. Although a substantial foundation of pallid sturgeon science has been developed during the past 20 years, our efforts attempt to push beyond that understanding to provide predictions of how future management actions may affect pallid sturgeon responses. For some of the 21 hypotheses, lines of evidence are limited to theoretical deduction, inference from sparse empirical datasets, or expert opinion. Useful simulation models have been developed to predict the effects of management actions on survival of drifting pallid sturgeon free embryos in the Yellowstone and Upper Missouri River complex (hereafter referred to as the “upper river”), and to assess the effects of flow and channel reconfigurations on habitat availability in the Lower Missouri River, tributaries, and Mississippi River downstream of Gavins Point Dam (hereafter referred to as the “lower river”). A population model also has been developed that can be used to assess sensitivity of the population to survival of specific life stages, assess some hypotheses related to stocking decisions, and explore a limited number of management

  20. How moral disagreement may ground principled moral compromise

    DEFF Research Database (Denmark)

    Kappel, Klemens

    2017-01-01

    In an influential paper, Simon C. May forcefully argued that, properly understood, there can never be principled reasons for moral compromise (May 2005). While there may be pragmatic reasons for compromising that involve, for instance, concern for political expediency or for stability there are p......In an influential paper, Simon C. May forcefully argued that, properly understood, there can never be principled reasons for moral compromise (May 2005). While there may be pragmatic reasons for compromising that involve, for instance, concern for political expediency or for stability...... there are properly speaking no principled reasons to compromise. My aim in the paper is to show how principled moral compromise in the context of moral disagreements over policy options is possible. I argue that when we disagree, principled reasons favoring compromises or compromising can assume a more significant...

  1. Integrated Disposal Facility FY2010 Glass Testing Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, Eric M.; Bacon, Diana H.; Kerisit, Sebastien N.; Windisch, Charles F.; Cantrell, Kirk J.; Valenta, Michelle M.; Burton, Sarah D.; Serne, R Jeffrey; Mattigod, Shas V.

    2010-09-30

    Pacific Northwest National Laboratory was contracted by Washington River Protection Solutions, LLC to provide the technical basis for estimating radionuclide release from the engineered portion of the disposal facility (e.g., source term). Vitrifying the low-activity waste at Hanford is expected to generate over 1.6 × 105 m3 of glass (Puigh 1999). The volume of immobilized low-activity waste (ILAW) at Hanford is the largest in the DOE complex and is one of the largest inventories (approximately 0.89 × 1018 Bq total activity) of long-lived radionuclides, principally 99Tc (t1/2 = 2.1 × 105), planned for disposal in a low-level waste (LLW) facility. Before the ILAW can be disposed, DOE must conduct a performance assessement (PA) for the Integrated Disposal Facility (IDF) that describes the long-term impacts of the disposal facility on public health and environmental resources. As part of the ILAW glass testing program PNNL is implementing a strategy, consisting of experimentation and modeling, in order to provide the technical basis for estimating radionuclide release from the glass waste form in support of future IDF PAs. The purpose of this report is to summarize the progress made in fiscal year (FY) 2010 toward implementing the strategy with the goal of developing an understanding of the long-term corrosion behavior of low-activity waste glasses. The emphasis in FY2010 was the completing an evaluation of the most sensitive kinetic rate law parameters used to predict glass weathering, documented in Bacon and Pierce (2010), and transitioning from the use of the Subsurface Transport Over Reactive Multi-phases to Subsurface Transport Over Multiple Phases computer code for near-field calculations. The FY2010 activities also consisted of developing a Monte Carlo and Geochemical Modeling framework that links glass composition to alteration phase formation by 1) determining the structure of unreacted and reacted glasses for use as input information into Monte Carlo

  2. Integrated Reporting and Assurance of Sustainability Information: An Experimental Study on Professional Investors’ Information Processing

    NARCIS (Netherlands)

    Reimsbach, D.; Hahn, R.; Gürtürk, A.

    2017-01-01

    Sustainability-related non-financial information is increasingly deemed value relevant. Against this background, two recent trends in non-financial reporting are frequently discussed: integrated reporting and assurance of sustainability information. Using an established framework of information acqu

  3. Integrated Nuclear-Renewable Energy Systems: Foundational Workshop Report

    Energy Technology Data Exchange (ETDEWEB)

    Bragg-Sitton, Shannon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boardman, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ruth, Mark [National Renewable Energy Lab. (NREL), Golden, CO (United States); Zinaman, Owen [National Renewable Energy Lab. (NREL), Golden, CO (United States); Forsberg, Charles [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Collins, John [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-08-01

    The U.S. Department of Energy (DOE) recognizes the need to transform the energy infrastructure of the U.S. and elsewhere to systems that can drastically reduce environmental impacts in an efficient and economically viable manner while utilizing both hydrocarbon resources and clean energy generation sources. Thus, DOE is supporting research and development that could lead to more efficient utilization of clean energy generation sources, including renewable and nuclear options. A concept being advanced by the DOE Offices of Nuclear Energy (NE) and Energy Efficiency and Renewable Energy (EERE) is tighter coupling of nuclear and renewable energy sources in a manner that produces new energy currency for the combined electricity grid, industrial manufacturing, and the transportation energy sectors. This integration concept has been referred to as a “hybrid system” that is capable of providing the right type of energy, at the right time, in the right place. At the direction of DOE-NE and DOE-EERE leadership, project leads at Idaho National Laboratory (INL), National Renewable Energy Laboratory (NREL) and Massachusetts Institute of Technology (MIT) have identified and engaged stakeholders in discussing integrated energy systems that would optimize renewable and nuclear energy integration on a region-by-region basis. Subsequent work will entail conduct of technical, economic, environmental and socio-political evaluations of the leading integrated system options based on a set of criteria established with stakeholder input. The Foundational Workshop for Integrated Nuclear – Renewable Energy Systems was organized around the following objectives: 1. Identify and refine priority region-specific opportunities for integrated nuclear-renewable energy systems in the U.S.; 2. Select Figures of Merit (FOM) to rank and prioritize candidate systems; 3. Discuss enabling technology development needs; 4. Identify analysis requirements, capabilities and gaps to estimate FOM for

  4. 40 CFR 13.26 - Payment of compromised claims.

    Science.gov (United States)

    2010-07-01

    ... will be required to execute a confess-judgment agreement which accelerates payment of the balance due... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Payment of compromised claims. 13.26... STANDARDS Compromise of Debts § 13.26 Payment of compromised claims. The Administrator normally will not...

  5. Strained Compromises? Danish Flexicurity During Crisis

    DEFF Research Database (Denmark)

    Ibsen, Christian Lyhne

    2011-01-01

    The Danish concept of flexicurity in a ‘Golden Triangle’ of low job protection, high income security and high employment security is not only about a balance between labor market flexibility and social security. Arguably, it is also a series of more or less stable underlying compromises between....... The article therefore introduces, ‘centralized decentralization’ – a concept that directs our attention to forms of flexibility and security primarily for people in work. Most studies on Danish flexicurity have been carried out under favorable economic conditions. In light of the economic slump hitting....... For example the case studies show that the hypothesized preference for external numerical flexibility is perhaps too crude as employers use different ways to restructure employment. Especially the examples of de facto concessionary bargaining to save jobs are important here – although the extent...

  6. Morgellons: contested illness, diagnostic compromise and medicalisation.

    Science.gov (United States)

    Fair, Brian

    2010-05-01

    The case of Morgellons illustrates how the emergence of a new medically contested illness intersected with and impacted on the diagnostic processes of an existing uncontested psychiatric condition, Delusional Parasitosis (DP). More specifically, the sociopolitical processes at play in the contested illness, Morgellons, dubiously reflect patient empowerment, as well the resilience and power of medical jurisdiction. This research offers insights into the contested illness and medicalisation literatures, and aims to bridge these two approaches towards the relationship between patient empowerment and medical authority, which I do through the notion of doctor-patient compromise. The data for this research come from a comprehensive qualitative analysis of Morgellons discourse through four key sources: the pro-Morgellons website Morgellons.org; the anti-Morgellons website Morgellonswatch.com; the popular media's portrayal of Morgellons; and the DP and Morgellons articles published in peer-reviewed medical journals, as made available on PubMed.

  7. A Commentary on "Integrated Reporting: A Review of Developments and Their Implications for the Accounting Curriculum"

    Science.gov (United States)

    Kamp-Roelands, Nancy

    2013-01-01

    In this commentary, Kamp-Roelands states that it was very encouraging to observe that the Association of Chartered Certified Accountants (ACCA) recognises that responding to "Integrated Reporting" initiatives requires an "integrated approach" to accounting education. That change in financial reporting standards put pressure on…

  8. A lot of icing but little cake? Taking integrated reporting forward

    NARCIS (Netherlands)

    P.M. Perego (Paolo); S.P. Kennedy (Steve); G.M. Whiteman (Gail)

    2016-01-01

    textabstractIntegrated reporting has fast emerged as a new accounting practice to help firms understand how they create value and be able to effectively communicate this to external stakeholders. While insightful experiences from the early-adopters of integrated reporting start to accumulate, the de

  9. INTEGRAL reports renewed activity from KS 1741-293

    DEFF Research Database (Denmark)

    Chenevez, Jérôme; Kuulkers, E.; Alfonso-Garzón, J.

    2010-01-01

    The low-mass X-ray binary and burster source KS 1741-293 has been detected during recent INTEGRAL Galactic bulge (see ATel #438) observations by the JEM-X instrument. On February 25, 2010, between UTC 13:04 and 14:08, KS 1741-293 was detected at a 3-10 keV flux of 9 +/- 4 mCrab, and an upper limit...... in the same energy bands. The region will be observed again by INTEGRAL on March 10, and the regular INTEGRAL monitoring of the Galactic bulge will continue until April 17, 2010. We encourage follow-up observations of this source at all wavelengths....

  10. INTEGRAL reports renewed activity from KS 1741-293

    DEFF Research Database (Denmark)

    Chenevez, Jérôme; Kuulkers, E.; Alfonso-Garzón, J.;

    2010-01-01

    The low-mass X-ray binary and burster source KS 1741-293 has been detected during recent INTEGRAL Galactic bulge (see ATel #438) observations by the JEM-X instrument. On February 25, 2010, between UTC 13:04 and 14:08, KS 1741-293 was detected at a 3-10 keV flux of 9 +/- 4 mCrab, and an upper limi...... in the same energy bands. The region will be observed again by INTEGRAL on March 10, and the regular INTEGRAL monitoring of the Galactic bulge will continue until April 17, 2010. We encourage follow-up observations of this source at all wavelengths....

  11. Grand challenges for integrated USGS science—A workshop report

    Science.gov (United States)

    Jenni, Karen E.; Goldhaber, Martin B.; Betancourt, Julio L.; Baron, Jill S.; Bristol, R. Sky; Cantrill, Mary; Exter, Paul E.; Focazio, Michael J.; Haines, John W.; Hay, Lauren E.; Hsu, Leslie; Labson, Victor F.; Lafferty, Kevin D.; Ludwig, Kristin A.; Milly, Paul C.; Morelli, Toni L.; Morman, Suzette A.; Nassar, Nedal T.; Newman, Timothy R.; Ostroff, Andrea C.; Read, Jordan S.; Reed, Sasha C.; Shapiro, Carl D.; Smith, Richard A.; Sanford, Ward E.; Sohl, Terry L.; Stets, Edward G.; Terando, Adam J.; Tillitt, Donald E.; Tischler, Michael A.; Toccalino, Patricia L.; Wald, David J.; Waldrop, Mark P.; Wein, Anne; Weltzin, Jake F.; Zimmerman, Christian E.

    2017-06-30

    Executive SummaryThe U.S. Geological Survey (USGS) has a long history of advancing the traditional Earth science disciplines and identifying opportunities to integrate USGS science across disciplines to address complex societal problems. The USGS science strategy for 2007–2017 laid out key challenges in disciplinary and interdisciplinary arenas, culminating in a call for increased focus on a number of crosscutting science directions. Ten years on, to further the goal of integrated science and at the request of the Executive Leadership Team (ELT), a workshop with three dozen invited scientists spanning different disciplines and career stages in the Bureau convened on February 7–10, 2017, at the USGS John Wesley Powell Center for Analysis and Synthesis in Fort Collins, Colorado.The workshop focused on identifying “grand challenges” for integrated USGS science. Individual participants identified nearly 70 potential grand challenges before the workshop and through workshop discussions. After discussion, four overarching grand challenges emerged:Natural resource security,Societal risk from existing and emerging threats,Smart infrastructure development, andAnticipatory science for changing landscapes.Participants also identified a “comprehensive science challenge” that highlights the development of integrative science, data, models, and tools—all interacting in a modular framework—that can be used to address these and other future grand challenges:Earth Monitoring, Analyses, and Projections (EarthMAP)EarthMAP is our long-term vision for an integrated scientific framework that spans traditional scientific boundaries and disciplines, and integrates the full portfolio of USGS science: research, monitoring, assessment, analysis, and information delivery.The Department of Interior, and the Nation in general, have a vast array of information needs. The USGS meets these needs by having a broadly trained and agile scientific workforce. Encouraging and supporting

  12. Dish Stirling system integration and test progress report

    Science.gov (United States)

    Haglund, R. A.

    1982-01-01

    The integration and check-out of a complete Dish Solar Stirling Thermal Power System is described. The preliminary results of the tests conducted thus far are presented. The results are very encouraging and show promise of high performance and efficiency. The outstanding performance and durability of the 4-95 Stirling engine was the highlight of this 6 month integration and test activity. Exposure to severe heat, dust, sand and wind during the summer months and heavy rains, high winds, including sand storms and freezing cold in recent months did affected the engine or the receiver in any noticable manner.

  13. General support for integrated assessment research. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Dowlatabadi, Hadi

    2001-03-01

    The climate change problem spans an extraordinarily large number of disciplines from earth sciences to social and political sciences. The interaction of processes described by these different fields is why climate change is such a complex issue. Keeping track of these interactions and bringing coherence to the assumptions underlying each disciplinary insight on the climate problem is a massive undertaking. Integrated assessment is an interdisciplinary approach designed to provide systematic evaluations of technically complex problems such as the analysis of environmental change challenges facing humanity. Ph.D. theses stemming from this application are summarized. Then some aspects of Integrated Climate Assessment Models are described.

  14. Buried waste integrated demonstration human engineered control station. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    This document describes the Human Engineered Control Station (HECS) project activities including the conceptual designs. The purpose of the HECS is to enhance the effectiveness and efficiency of remote retrieval by providing an integrated remote control station. The HECS integrates human capabilities, limitations, and expectations into the design to reduce the potential for human error, provides an easy system to learn and operate, provides an increased productivity, and reduces the ultimate investment in training. The overall HECS consists of the technology interface stations, supporting engineering aids, platform (trailer), communications network (broadband system), and collision avoidance system.

  15. Integration of metabolome data with metabolic networks reveals reporter reactions

    DEFF Research Database (Denmark)

    Çakir, Tunahan; Patil, Kiran Raosaheb; Önsan, Zeynep Ilsen;

    2006-01-01

    Interpreting quantitative metabolome data is a difficult task owing to the high connectivity in metabolic networks and inherent interdependency between enzymatic regulation, metabolite levels and fluxes. Here we present a hypothesis-driven algorithm for the integration of such data with metabolic...

  16. Sarcoidosis with Major Airway, Vascular and Nerve Compromise

    Directory of Open Access Journals (Sweden)

    Hiroshi Sekiguchi

    2013-01-01

    Full Text Available The present report describes a 60-year-old Caucasian woman who presented with progressive dyspnea, cough and wheeze. A computed tomography scan of the chest showed innumerable bilateral inflammatory pulmonary nodules with bronchovascular distribution and a mediastinal and hilar infiltrative process with calcified lymphadenopathy leading to narrowing of lobar bronchi and pulmonary arteries. An echocardiogram revealed pulmonary hypertension. Bronchoscopy showed left vocal cord paralysis and significant narrowing of the bilateral bronchi with mucosal thickening and multiple nodules. Transbronchial biopsy was compatible with sarcoidosis. Despite balloon angioplasty of the left lower lobe and pulmonary artery, and medical therapy with oral corticosteroids, her symptoms did not significantly improve. To the authors’ knowledge, the present report describes the first case of pulmonary sarcoidosis resulting in major airway, vascular and nerve compromise due to compressive lymphadenopathy and suspected concurrent granulomatous infiltration. Its presentation mimicked idiopathic mediastinal fibrosis.

  17. Quality management tools: facilitating clinical research data integrity by utilizing specialized reports with electronic case report forms.

    Science.gov (United States)

    Trocky, N M; Fontinha, M

    2005-01-01

    Data collected throughout the course of a clinical research trial must be reviewed for accuracy and completeness continually. The Oracle Clinical (OC) data management application utilized to capture clinical data facilitates data integrity through pre-programmed validations, edit and range checks, and discrepancy management modules. These functions were not enough. Coupled with the use of specially created reports in Oracle Discoverer and Integrated Review, both ad-hoc query and reporting tools, research staff have enhanced their ability to clean, analyze and report more accurate data captured within and among Case Report Forms (eCRFs) by individual study or across multiple studies.

  18. Organizational and methodical approaches to disclosure of income distribution in integrated reporting

    Directory of Open Access Journals (Sweden)

    Legenchyk S.F.

    2017-08-01

    Full Text Available The essence of the integrated reporting is described. Preconditions and problems when introducing the integrated reporting are presented. The information requests of integrated reporting users are described. The necessity of reflection of all types of capital, namely, natural, social, human and intellectual in the integrated reporting are revealed. The main advantages of compiling the integrated accounts for the enterprise are established: a broader perspective of consideration of the activity; the improvement of accounting policy as a result of integration of the principles of sustainable development into activity; increasing the trust of workers and consumers in the safety of technological processes and products for environment. For the wider introduction of the integrated reporting it is necessary to develop the methodological provision for accounting in accordance with the principles of sustainable development to ensure the reliability of the indices obtained; it is necessary to select the optimal list of indices that can meet the information needs of all users, in particular, investors, the state, auditors, society, creditors, consumers, employees, management personnel, academics, and the media. The main tasks and principles of compilation of the integrated reporting are presented. Orientation to the future, materiality, demand, integrity, reliability, completeness, periodicity, consistency, timeliness, interpretation, and comparability are suggested as the principles of integrated reporting. The issue of the necessity of conducting the external audit of the data verification of the integrity reporting is highlighted. The algorithm of profit distribution depending on the chosen strategy of enterprise development is proposed. When directing net profits for the development of production, the authors identify the following three strategies: insufficient upgrades, upgrades at the level of wear and the advanced renewal of non-current assets. It

  19. Developing IntegRATE: a fast and frugal patient-reported measure of integration in health care delivery

    Directory of Open Access Journals (Sweden)

    Glyn Elwyn

    2015-03-01

    Full Text Available Background: Efforts have been made to measure integration in health care delivery, but few existing instruments have adopted a patient perspective, and none is sufficiently generic and brief for administration at scale. We sought to develop a brief and generic patient-reported measure of integration in health care delivery.Methods: Drawing on both existing conceptualisations of integrated care and research on patients’ perspectives, we chose to focus on four distinct domains of integration: information sharing,consistent advice, mutual respect and role clarity. We formulated candidate items and conducted cognitive interviews with end users to further develop and refine the items. We then pilot-tested the measure.Results: Four rounds of cognitive interviews were conducted (n = 14 and resulted in a four-item measure that was both relevant and understandable to end users. The pilot administration of the measure (n = 15 further confirmed the relevance and interpretability of items and demonstrated that the measure could be completed in less than one minute.Conclusions: This new measure, IntegRATE, represents a patient-reported measure of integration in health care delivery that is conducive to use in both routine performance monitoring and research. The psychometric properties of the measure will be assessed in the next stage of development. 

  20. FY-94 buried waste integrated demonstration program report

    Energy Technology Data Exchange (ETDEWEB)

    1994-11-01

    The Buried Waste Integrated Demonstration (BWID) supports the applied research, development, demonstration, and evaluation of a multitude of advanced technologies. These technologies are being integrated to form a comprehensive remediation system for the effective and efficient remediation of buried waste. These efforts are identified and coordinated in support of the U.S. Department of Energy (DOE), Environmental Restoration and Waste Management (ER/WM) needs and objectives. This document summarizes previous demonstrations and describes the FY-94 BWID technology development and demonstration activities. Sponsored by the DOE Office of Technology Development (OTD), BWID works with universities and private industry to develop these technologies, which are being transferred to the private sector for use nationally and internationally. A public participation policy has been established to provide stakeholders with timely and accurate information and meaningful opportunities for involvement in the technology development and demonstration process.

  1. Spacelab software development and integration concepts study report, volume 1

    Science.gov (United States)

    Rose, P. L.; Willis, B. G.

    1973-01-01

    The proposed software guidelines to be followed by the European Space Research Organization in the development of software for the Spacelab being developed for use as a payload for the space shuttle are documented. Concepts, techniques, and tools needed to assure the success of a programming project are defined as they relate to operation of the data management subsystem, support of experiments and space applications, use with ground support equipment, and for integration testing.

  2. Progress Report 15, December 1979-April 1980, and proceedings of the fifteenth Project Integration Meeting

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    Progress made by the Low-Cost Solar Array Project during the period December 1979 to April 1980 is reported. Reports on project analysis and integration; technology development in silicon material, large-area silicon sheet and encapsulation; production process and equipment development; engineering; and operations are included. Also, a report on, and copies of visual presentations made at, the Project Integration Meeting held April 2 and 3, 1980, are included.

  3. Green Lighting. Energy-efficient integrated lighting systems - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Linhart, F.; Scartezzini, J.-L.

    2009-10-15

    The objective of the Green Lighting project was to develop a High Performance Integrated Lighting System, based on advanced technologies for day- and electric lighting, achieving a Lighting Power Density (LPD) that does not exceed 3 W/m{sup 2}. The project has revealed that Anidolic Daylighting Systems (ADS) are an ideal basis for High Performance Integrated Lighting Systems. Not only are they able to provide adequate illumination (i.e. sufficiently high illuminance) in office rooms during large fractions of normal office hours, under various sky conditions and over the entire year, but they are also highly appreciated by office occupants at the condition that glare control mechanisms are available. Complementary electric lighting is, however, still necessary to back up the ADS at times when there is insufficient daylight flux available. It was shown during this project, that the most interesting trade-offs between energy-efficiency and visual comfort are obtained by using a combination of ceiling-mounted directly emitting luminaires with very high optical efficiencies for ambient lighting and portable desk lamps for temporary task lighting. The most appropriate lamps for the ceiling-mounted luminaires are currently highly efficient fluorescent tubes, but white LED tubes can be considered a realistic option for the future. The most suitable light sources for desk lamps for temporary task lighting are Compact Fluorescent Lamps (CFLs) and white LED light bulbs. Based on the above-mentioned technologies, a High Performance Integrated Lighting System with a very low LPD has been developed over the last three years. The system has been set up in an office room of the LESO solar experimental building located on the EPFL campus; it has been tested intensively during a Post-Occupancy Evaluation (POE) study involving twenty human subjects. This study has revealed that the subjects' performance and subjective visual comfort was improved by the new system, compared to

  4. Resort Project Selection by Using Compromise Programming

    Directory of Open Access Journals (Sweden)

    Gabrijela Popović

    2017-07-01

    Full Text Available Serbia is a landlocked country deprived of the possibility of developing maritime tourism. On the other hand, it has the opportunity to develop the other types of tourism, such as: mountain tourism, spa tourism, rural tourism, etc. Serbia has to improve its tourism infrastructure in order to achieve better quality and meet tourists’ requirements. In that sense, it is necessary to enhance the number of the accommodation facilities that will meet set standards. The selection of the type of the accommodation facility, as well as its location, is a very delicate issue because the right choice influences future operations and revenue. Making a decision without considering the problem from every available aspect could lead to making the wrong decisions. Multiple Criteria Decision Making methods are imposed as the logical approach to solving problems in an effective manner. In this paper, the ranking and selection of the optimal resort project focused on the tourism development of Bačka and is performed using compromise programming.

  5. Conflicting perspectives compromising discussions on cardiopulmonary resuscitation.

    LENUS (Irish Health Repository)

    Groarke, J

    2010-09-01

    Healthcare professionals, patients and their relatives are expected to discuss resuscitation together. This study aims to identify the differences in the knowledge base and understanding of these parties. Questionnaires examining knowledge and opinion on resuscitation matters were completed during interviews of randomly selected doctors, nurses and the general public. 70% doctors, 24% nurses and 0% of a public group correctly estimated survival to discharge following in-hospital resuscitation attempts. Deficiencies were identified in doctor and nurse knowledge of ethics governing resuscitation decisions. Public opinion often conflicts with ethical guidelines. Public understanding of the nature of cardiopulmonary arrests and resuscitation attempts; and of the implications of a \\'Do Not Attempt Resuscitation (DNAR)\\' order is poor. Television medical dramas are the primary source of resuscitation knowledge. Deficiencies in healthcare professionals\\' knowledge of resuscitation ethics and outcomes may compromise resuscitation decisions. Educational initiatives to address deficiencies are necessary. Parties involved in discussion on resuscitation do not share the same knowledge base reducing the likelihood of meaningful discussion. Public misapprehensions surrounding resuscitation must be identified and corrected during discussion.

  6. Dynamics of discrete opinions without compromise

    CERN Document Server

    Öztürk, M Kaan

    2011-01-01

    A new agent-based, bounded-confidence model for discrete one-dimensional opinion dynamics is presented. The agents interact if their opinions do not differ more than a tolerance parameter. In pairwise interactions, one of the pair, randomly selected, converts to the opinion of the other. The model can be used to simulate cases where no compromise is possible, such as exclusive choices or competing brands. The fully-mixed case with maximum tolerance is equivalent to the Gambler's Ruin problem. A fully-mixed system always ends up in an absorbing state, which can have one or more surviving opinions. An upper bound for the final number of opinions is given. The distribution of absorption times fits the generalized extreme value distribution. The diffusion coefficient of an opinion increases linearly with the number of opinions within the tolerance parameter. A general master equation and specific Markov matrices are given. The software code developed for this study is provided as a supplement.

  7. 2014 Annual Report: Integrated Waterbird Management and Monitoring Initiative

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual report provides information on the IWMM initiative including monitoring efforts and observations, ongoing protocol revisions, development of the National...

  8. Solid waste integrated cost analysis model: 1991 project year report

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    The purpose of the City of Houston's 1991 Solid Waste Integrated Cost Analysis Model (SWICAM) project was to continue the development of a computerized cost analysis model. This model is to provide solid waste managers with tool to evaluate the dollar cost of real or hypothetical solid waste management choices. Those choices have become complicated by the implementation of Subtitle D of the Resources Conservation and Recovery Act (RCRA) and the EPA's Integrated Approach to managing municipal solid waste;. that is, minimize generation, maximize recycling, reduce volume (incinerate), and then bury (landfill) only the remainder. Implementation of an integrated solid waste management system involving all or some of the options of recycling, waste to energy, composting, and landfilling is extremely complicated. Factors such as hauling distances, markets, and prices for recyclable, costs and benefits of transfer stations, and material recovery facilities must all be considered. A jurisdiction must determine the cost impacts of implementing a number of various possibilities for managing, handling, processing, and disposing of waste. SWICAM employs a single Lotus 123 spreadsheet to enable a jurisdiction to predict or assess the costs of its waste management system. It allows the user to select his own process flow for waste material and to manipulate the model to include as few or as many options as he or she chooses. The model will calculate the estimated cost for those choices selected. The user can then change the model to include or exclude waste stream components, until the mix of choices suits the user. Graphs can be produced as a visual communication aid in presenting the results of the cost analysis. SWICAM also allows future cost projections to be made.

  9. Treatment of Lung Cancer in Medically Compromised Patients.

    Science.gov (United States)

    Crawford, Jeffrey; Wheatley-Price, Paul; Feliciano, Josephine Louella

    2016-01-01

    Outcomes for patients with lung cancer have been improved substantially through the integration of surgery, radiation, and systemic therapy for patients with early-stage disease. Meanwhile, advances in our understanding of molecular mechanisms have substantially advanced our treatment of patients with advanced lung cancer through the introduction of targeted therapies, immune approaches, improvements in chemotherapy, and better supportive care. However, the majority of these advances have occurred among patients with good functional status, normal organ function, and with the social and economic support systems to be able to benefit most from these treatments. The aim of this article is to bring greater attention to management of lung cancer in patients who are medically compromised, which remains a major barrier to care delivery. Impaired performance status is associated with poor outcomes and correlates with the high prevalence of cachexia among patients with advanced lung cancer. CT imaging is emerging as a research tool to quantify muscle loss in patients with cancer, and new therapeutics are on the horizon that may provide important adjunctive therapy in the future. The benefits of cancer therapy for patients with organ failure are poorly understood because of their exclusion from clinical trials. The availability of targeted therapy and immunotherapy may provide alternatives that may be easier to deliver in this population, but clinical trials of these new agents in this population are vital. Patients with lower socioeconomic status are disproportionately affected by lung cancer because of higher rates of tobacco addiction and the impact of socioeconomic status on delay in diagnosis, treatment, and outcomes. For all patients who are medically compromised with lung cancer, multidisciplinary approaches are particularly needed to evaluate these patients and to incorporate rapidly changing therapeutics to improve outcomes.

  10. Business Case for Integrated Reporting in the Nigerian Oil and Gas Sector

    Directory of Open Access Journals (Sweden)

    Tajudeen J. AYOOLA

    2013-03-01

    were sourced from the annual reports and stand-alone sustainability reports of the six multinational companies operating in the Nigerian oil and gas sector. The results found that efforts to address environmental, social and governance reporting (ESG were adhoc, short term and unrelated to the core activities of the corporations and as such were not integrated into their business strategies and model. Information on ESG was also duplicated over many medium in a haphazard and distorted form. The study therefore concluded that the introduction of integrated reporting will streamline performance reporting that is in line with international best practice in the sector.

  11. Vertically integrated analysis of human DNA. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Olson, M.

    1997-10-01

    This project has been oriented toward improving the vertical integration of the sequential steps associated with the large-scale analysis of human DNA. The central focus has been on an approach to the preparation of {open_quotes}sequence-ready{close_quotes} maps, which is referred to as multiple-complete-digest (MCD) mapping, primarily directed at cosmid clones. MCD mapping relies on simple experimental steps, supported by advanced image-analysis and map-assembly software, to produce extremely accurate restriction-site and clone-overlap maps. We believe that MCD mapping is one of the few high-resolution mapping systems that has the potential for high-level automation. Successful automation of this process would be a landmark event in genome analysis. Once other higher organisms, paving the way for cost-effective sequencing of these genomes. Critically, MCD mapping has the potential to provide built-in quality control for sequencing accuracy and to make possible a highly integrated end product even if there are large numbers of discontinuities in the actual sequence.

  12. Factory-built integrated solar homes - A progress report

    Energy Technology Data Exchange (ETDEWEB)

    Rawlings, L.K.

    1995-12-31

    Over the past fifteen years, hundreds of people across the US have built for themselves highly advanced residences which integrated passive solar architecture; photovoltaic power systems; high-efficiency lights, appliances, and HVAC (heating, ventilating, and cooling) equipment; high-level insulation and airtight construction; and other renewable energy and energy-efficient technologies. Such a home can be referred to as an {open_quotes}integrated solar home{close_quotes}. As the essential technologies have improved in performance, price, and availability, the performance of such homes has steadily advanced to the point where they could provide amenities at more-or-less normal US standards of luxury, yet require as little as 5% to 10% of the level of fossil fuel or biomass use that are required in an average US home. However, the resources required to build such a home, both in terms of the time and dedication needed for research, design, and construction of the homes, and in terms of the additional cost of the renewable energy/energy efficient features, have prevented such construction from moving beyond a tiny handful of highly motivated homeowners and into the mainstream of residential construction. This paper has design summaries of six different houses.

  13. Weirton Steel Corporation logistics and integrated scheduling. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Guzzetta, M.B. [comp.

    1996-06-01

    In order to remain competitive in the changing steel market, US steel producers restructured by taking on foreign and domestic partners, closing facilities and/or trimming work forces, and modernizing their steel making facilities. However, very little was done to develop production management technology to complement these changes. The Logistics and Integrated Scheduling program (LIS) was undertaken to address this issue. LIS is an information management system that delivers better customer service, better quality materials, and a just-in-time delivery system. It involves three major components: (1) material marking and sensing: advanced R&D applied to determining cost effective, feasible solutions to passive inventory; (2) material inventory and tracking: advanced technology applied to managing inventory movement; (3) planning and scheduling: beginning with annual production plans, order management, and operational constraints, the ability to build integrated schedules capable of pull through and push through scheduling for various plant capability levels and location configurations with rapid turnaround capability. LIS provides accurate, automated tracking of material flows throughout the mill, the collection and analysis of production data, and automated schedule optimization.

  14. Building America Systems Integration Research Annual Report: FY 2012

    Energy Technology Data Exchange (ETDEWEB)

    Gestwick, M.

    2013-05-01

    This document is the Building America FY2012 Annual Report, which includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.

  15. Building America Systems Integration Research Annual Report. FY 2012

    Energy Technology Data Exchange (ETDEWEB)

    Gestwick, Michael [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-05-01

    This Building America FY2012 Annual Report includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.

  16. Status Report on NEAMS PROTEUS/ORIGEN Integration

    Energy Technology Data Exchange (ETDEWEB)

    Wieselquist, William A [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-02-18

    The US Department of Energy’s Nuclear Energy Advanced Modeling and Simulation (NEAMS) Program has contributed significantly to the development of the PROTEUS neutron transport code at Argonne National Laboratory and to the Oak Ridge Isotope Generation and Depletion Code (ORIGEN) depletion/decay code at Oak Ridge National Laboratory. PROTEUS’s key capability is the efficient and scalable (up to hundreds of thousands of cores) neutron transport solver on general, unstructured, three-dimensional finite-element-type meshes. The scalability and mesh generality enable the transfer of neutron and power distributions to other codes in the NEAMS toolkit for advanced multiphysics analysis. Recently, ORIGEN has received considerable modernization to provide the high-performance depletion/decay capability within the NEAMS toolkit. This work presents a description of the initial integration of ORIGEN in PROTEUS, mainly performed during FY 2015, with minor updates in FY 2016.

  17. Amyris, Inc. Integrated Biorefinery Project Summary Final Report - Public Version

    Energy Technology Data Exchange (ETDEWEB)

    Gray, David; Sato, Suzanne; Garcia, Fernando; Eppler, Ross; Cherry, Joel

    2014-03-12

    The Amyris pilot-scale Integrated Biorefinery (IBR) leveraged Amyris synthetic biology and process technology experience to upgrade Amyris’s existing Emeryville, California pilot plant and fermentation labs to enable development of US-based production capabilities for renewable diesel fuel and alternative chemical products. These products were derived semi-synthetically from high-impact biomass feedstocks via microbial fermentation to the 15-carbon intermediate farnesene, with subsequent chemical finishing to farnesane. The Amyris IBR team tested and provided methods for production of diesel and alternative chemical products from sweet sorghum, and other high-impact lignocellulosic feedstocks, at pilot scale. This enabled robust techno-economic analysis (TEA), regulatory approvals, and a basis for full-scale manufacturing processes and facility design.

  18. Halogen control in integrated hot gas cleaning: final report

    Energy Technology Data Exchange (ETDEWEB)

    Nieminen, M.; Kangasmaa, K.; Laatikainen-Luntama, J.; Kurkela, E. [VTT Energy (Finland)

    1998-12-31

    A simple and cost effective dry-scrubbing halogen control method for hot gasification gas cleaning applications was developed. The work aimed to develop a dry scrubbing method for integration into a hot gas cleaning system including particulate removal by cyclones, filtration and possibly a desulphurisation system. Work started by determining the behaviour of halogen compounds in a reducing gasification atmosphere to evaluate the fate of halogens on downstream components, to understand the role of halogens as precursors for environmental emissions, and to give background information for developing halogen control methods. New halogen sampling and analysis methods for pressurised gasification gas conditions were also developed. Mass balances were determined for several gasification conditions, with and without calcium-based bed additives. Several potential dry scrubbing sorbent candidates were evaluated. Chemical, technical, economical and environmental aspects were used as selection criteria, calcium-based sorbents being chosen for development of the halogen removal system. The process concept was based on sorbent feeding into the product gas prior to the hot gas filter unit, where the final step of halogen capture takes place and both sorbent and particulates are removed from the gas. Preliminary screening of calcium-based sorbents and preoptimisation of process conditions was performed in a laboratory scale dry scrubbing test rig. Finally, the performance of the developed dry scrubbing halogen removal system was verified in a PDU scale pressurised fluidised bed gasification and gas cleaning test rig. Preliminary verification showed that, in favourable conditions, the system developed formed a potential halogen control system that could be easily integrated into the other hot gas cleaning systems. 2 refs., 9 figs., 2 tabs.

  19. Integrating Business Core Knowledge through Upper Division Report Composition

    Science.gov (United States)

    Roach, Joy; Tracy, Daniel; Durden, Kay

    2007-01-01

    The most ambitious project of many undergraduate business communication courses is the formal report. This assignment typically requires the use of many writing skills nurtured throughout the course. Skills such as proper style, tone, organization, flow, and mechanics are enhanced through the writing of memos and various types of letters. While…

  20. How to Integrate International Financial Reporting Standards into Accounting Programs

    Science.gov (United States)

    Singer, Robert A.

    2012-01-01

    It is expected the SEC will require U.S. domestic companies to prepare and file their annual 10Ks in accordance with international financial reporting standards (IFRS) by 2016. Given the probability that the FASB-IASB convergence project (i.e., Norwalk Agreement) will continue subsequent to mandatory adoption, US accounting programs will be…

  1. VISA Final Report: Fully Integrated Power Electronic Systems in Automotive Electronics

    NARCIS (Netherlands)

    Waffenschmidt, E.

    2011-01-01

    This report summarizes the activities related to the public funded project “Vollintegrierte leistungselektronische Systeme in der Automobilelektronik – VISA” (Fully Integrated Power Electronic Systems in Automotive Electronics). Aim of the project is to investigate the integration of components into

  2. EPA Issues November 15, 2010 Memorandum: Integrated Reporting and Listing Decisions Related to Ocean Acidification

    Science.gov (United States)

    The memorandum provides information to assist regions and states in preparing and reviewing Integrated Reports related to ocean acidification (OA) impacts under Sections 303(d), 305(b) and 314 of the Clean Water Act (CWA).

  3. Final technical report for DOE Computational Nanoscience Project: Integrated Multiscale Modeling of Molecular Computing Devices

    Energy Technology Data Exchange (ETDEWEB)

    Cummings, P. T.

    2010-02-08

    This document reports the outcomes of the Computational Nanoscience Project, "Integrated Multiscale Modeling of Molecular Computing Devices". It includes a list of participants and publications arising from the research supported.

  4. Aerial Measuring System Technical Integration Annual Report 2002

    Energy Technology Data Exchange (ETDEWEB)

    Bechtel Nevada Remote Sensing Laboratory

    2003-06-01

    Fiscal Year 2002 is the second year of a five-year commitment by the U.S. Department of Energy, National Nuclear Security Administration (NNSA) to invest in development of new and state-of-the-art technologies for the Aerial Measuring Systems (AMS) project. In 2000, NNSA committed to two million dollars for AMS Technical Integration (TI) for each of five years. The tragedy of September 11, 2001, profoundly influenced the program. NNSA redirected people and funding resources at the Remote Sensing Laboratory (RSL) to more immediate needs. Funds intended for AMS TI were redirected to NNSA's new posture of leaning further forward throughout. AMS TI was brought to a complete halt on December 10, 2001. Then on April 30, 2002, NNSA Headquarters allowed the restart of AMS TI at the reduced level of $840,000. The year's events resulted in a slow beginning of several projects, some of which were resumed only a few weeks before the AMS TI Symposium held at RSL on July 30.

  5. Ames Laboratory integrated safety management self-assessment report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    The implementation of Integrated Safety Management (ISM) at Ames Laboratory began with the signing of the ISM Implementation Charter on February 24, 1997 (see Appendix A). The first step toward implementation of ISM at Ames Laboratory is the performance of a Self-Assessment (SA). In preparation for the SA, a workshop on ISM was provided to the Laboratory`s Environment, Safety, and Health (ES&H) Coordinators, Safety Review Committee members, and the Environment, Safety, Health and Assurance (ESH&A) staff. In addition, a briefing was given to the Laboratory`s Executive Council and Program Directors. Next, an SA Team was organized. The Team was composed of four Ames Laboratory and four Department of Energy-Chicago Operations Office (DOE-CH) staff members. The purpose of this SA was to determine the current status of ES&H management within Ames Laboratory, as well as to identify areas which need to be improved during ISM implementation. The SA was conducted by reviewing documents, interviewing Ames Laboratory management and staff, and performing walkthroughs of Laboratory areas. At the conclusion of this SA, Ames Laboratory management was briefed on the strengths, weaknesses, and the areas of improvement which will assist in the implementation of ISM.

  6. Heat-pump-centered integrated community energy systems. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1979-11-01

    A Heat Pump Centered-Integrated Community Energy System (HP-ICES) concept was explored and developed that is based on use of privately owned ice-making heat pumps in each building or complex within a community. These heat pumps will provide all of the space heating, space cooling and domestic hot water needs. All of the community input energy required is provided by electrical power, thereby eliminating a community's dependence on gas or oil supplies. The heat pumps will operate in both air and water source modes, deriving performance advantages of both. The possible forms of an HP-ICES system, the technical and economic limitations, environmental impacts and other factors are discussed from a general viewpoint. The concept is applied to a specific planned community and its performance and economic features are examined in detail. It is concluded that the HP-ICES concept is technically viable, but that its economic desirability as compared with conventional heat pump systems is hampered by much higher initial costs, and that the economic feasibility of HP-ICES systems will depend on future fuel source costs and supply and on electric power rates. (LCL)

  7. Task 10 - technology development integration. Semi-annual report, April 1--September 30, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Hendrikson, J.G.; Daly, D.J.

    1997-05-01

    The Energy and Environmental Research Center (EERC), in conjunction with the Waste Policy Institute (WPI), will identify and integrate new technologies to meet site-specific environmental management (EM) requirements at contaminated sites appropriate to U.S. Department of Energy (DOE) interests. This paper briefly reports overall progress for three activities: technology management, project management, and technology integration. Work performed over the reporting period has focused on providing logistical and administrative support. In addition, six monthly WPI reports to the EERC are included as appendices. The WPI reports contained detailed information for progress in each activity.

  8. Nuclear design report for system-integrated modular advanced reactor

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sang Yoon; Lee, Chung Chan; Zee, Sung Quun; Chang, Moon Hee [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2002-02-01

    This report presents nuclear characteristics analysis results for SMART. Information is given on fuel loading, power density distributions, reactivity coefficients and control rod worths. The core consists of 57 modified Korean Standard Fuel Assemblies (m-KOFAs). and all fuel assemblies contain burnable absorbers to control the power distribution and the excess reactivity that is required for soluble boron-free and ultra longer cycle operation. The cycle length of SMART amounts to 990 EFPD corresponding to a cycle burnup of 26,160 MWD/MTU. 4 refs., 92 figs., 5 tabs. (Author)

  9. Integral Monitored Retrievable Storage (MRS) Facility conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1985-09-01

    In April 1985, the Department of Energy (DOE) selected the Clinch River site as its preferred site for the construction and operation of the monitored retrievable storage (MRS) facility (USDOE, 1985). In support of the DOE MRS conceptual design activity, available data describing the site have been gathered and analyzed. A composite geotechnical description of the Clinch River site has been developed and is presented herein. This report presents Clinch River site description data in the following sections: general site description, surface hydrologic characteristics, groundwater characteristics, geologic characteristics, vibratory ground motion, surface faulting, stability of subsurface materials, slope stability, and references. 48 refs., 35 figs., 6 tabs.

  10. Energy implications of integrated solid waste management systems. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Little, R.E.; McClain, G.; Becker, M.; Ligon, P.; Shapiro, K.

    1994-07-01

    This study develops estimates of energy use and recovery from managing municipal solid waste (MSW) under various collection, processing, and disposal scenarios. We estimate use and recovery -- or energy balance -- resulting from MSW management activities such as waste collection, transport, processing, and disposal, as well as indirect use and recovery linked to secondary materials manufacturing using recycled materials. In our analysis, secondary materials manufacturing displaces virgin materials manufacturing for 13 representative products. Energy implications are expressed as coefficients that measure the net energy saving (or use) of displacing products made from virgin versus recycled materials. Using data developed for the 1992 New York City Master Plan as a starting point, we apply our method to an analysis of various collection systems and 30 types of facilities to illustrate bow energy balances shift as management systems are modified. In sum, all four scenarios show a positive energy balance indicating the energy and advantage of integrated systems versus reliance on one or few technology options. That is, energy produced or saved exceeds the energy used to operate the solid waste system. The largest energy use impacts are attributable to processing, including materials separation and composting. Collection and transportation energy are relatively minor contributors. The largest two contributors to net energy savings are waste combustion and energy saved by processing recycled versus virgin materials. An accompanying spatial analysis methodology allocates energy use and recovery to New York City, New York State outside the city, the U.S., and outside the U.S. Our analytical approach is embodied in a spreadsheet model that can be used by energy and solid waste analysts to estimate impacts of management scenarios at the state and substate level.

  11. State-of-the-Art Report on Ethics of Research Integrity

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Hyuk; Hahn, K. W.; Nam, Y. M.; You, B. H.; Min, B. J

    2006-04-15

    The report briefly considers the generous ethical issues such as the background of philosophy, the issues of research ethics, the research integrity, the role of citation, the program and the code of research ethics. The report introduces the background of philosophy of science and elements of research ethics. It also considers the precedents of misconduct in research ethics and the ingredients to preserve the research integrity. Especially, the citation with obscure boundary between proper citation and plagiarism is carefully explored through several examples. Finally, the domestic ethics conditions are investigated on the research integrity and educational program on the responsible conduct of research. To compare the domestic situation, the educational program and the system of research integrity in EU and USA are deeply searched in Ch. 6 and Appendix III and V. To develop an educational program of research ethics and integrity, Nuclear Training Centre(NTC) collects and arranges the material and resource for research ethics.

  12. Methamphetamine compromises gap junctional communication in astrocytes and neurons.

    Science.gov (United States)

    Castellano, Paul; Nwagbo, Chisom; Martinez, Luis R; Eugenin, Eliseo A

    2016-05-01

    Methamphetamine (meth) is a central nervous system (CNS) stimulant that results in psychological and physical dependency. The long-term effects of meth within the CNS include neuronal plasticity changes, blood-brain barrier compromise, inflammation, electrical dysfunction, neuronal/glial toxicity, and an increased risk to infectious diseases including HIV. Most of the reported meth effects in the CNS are related to dysregulation of chemical synapses by altering the release and uptake of neurotransmitters, especially dopamine, norepinephrine, and epinephrine. However, little is known about the effects of meth on connexin (Cx) containing channels, such as gap junctions (GJ) and hemichannels (HC). We examined the effects of meth on Cx expression, function, and its role in NeuroAIDS. We found that meth altered Cx expression and localization, decreased GJ communication between neurons and astrocytes, and induced the opening of Cx43/Cx36 HC. Furthermore, we found that these changes in GJ and HC induced by meth treatment were mediated by activation of dopamine receptors, suggesting that dysregulation of dopamine signaling induced by meth is essential for GJ and HC compromise. Meth-induced changes in GJ and HC contributed to amplified CNS toxicity by dysregulating glutamate metabolism and increasing the susceptibility of neurons and astrocytes to bystander apoptosis induced by HIV. Together, our results indicate that connexin containing channels, GJ and HC, are essential in the pathogenesis of meth and increase the sensitivity of the CNS to HIV CNS disease. Methamphetamine (meth) is an extremely addictive central nervous system stimulant. Meth reduced gap junctional (GJ) communication by inducing internalization of connexin-43 (Cx43) in astrocytes and reducing expression of Cx36 in neurons by a mechanism involving activation of dopamine receptors (see cartoon). Meth-induced changes in Cx containing channels increased extracellular levels of glutamate and resulted in higher

  13. Mitigating Reptile Road Mortality: Fence Failures Compromise Ecopassage Effectiveness

    Science.gov (United States)

    Baxter-Gilbert, James H.; Riley, Julia L.; Lesbarrères, David; Litzgus, Jacqueline D.

    2015-01-01

    Roadways pose serious threats to animal populations. The installation of roadway mitigation measures is becoming increasingly common, yet studies that rigorously evaluate the effectiveness of these conservation tools remain rare. A highway expansion project in Ontario, Canada included exclusion fencing and ecopassages as mitigation measures designed to offset detrimental effects to one of the most imperial groups of vertebrates, reptiles. Taking a multispecies approach, we used a Before-After-Control-Impact study design to compare reptile abundance on the highway before and after mitigation at an Impact site and a Control site from 1 May to 31 August in 2012 and 2013. During this time, radio telemetry, wildlife cameras, and an automated PIT-tag reading system were used to monitor reptile movements and use of ecopassages. Additionally, a willingness to utilize experiment was conducted to quantify turtle behavioral responses to ecopassages. We found no difference in abundance of turtles on the road between the un-mitigated and mitigated highways, and an increase in the percentage of both snakes and turtles detected dead on the road post-mitigation, suggesting that the fencing was not effective. Although ecopassages were used by reptiles, the number of crossings through ecopassages was lower than road-surface crossings. Furthermore, turtle willingness to use ecopassages was lower than that reported in previous arena studies, suggesting that effectiveness of ecopassages may be compromised when alternative crossing options are available (e.g., through holes in exclusion structures). Our rigorous evaluation of reptile roadway mitigation demonstrated that when exclusion structures fail, the effectiveness of population connectivity structures is compromised. Our project emphasizes the need to design mitigation measures with the biology and behavior of the target species in mind, to implement mitigation designs in a rigorous fashion, and quantitatively evaluate road

  14. Mitigating reptile road mortality: fence failures compromise ecopassage effectiveness.

    Directory of Open Access Journals (Sweden)

    James H Baxter-Gilbert

    Full Text Available Roadways pose serious threats to animal populations. The installation of roadway mitigation measures is becoming increasingly common, yet studies that rigorously evaluate the effectiveness of these conservation tools remain rare. A highway expansion project in Ontario, Canada included exclusion fencing and ecopassages as mitigation measures designed to offset detrimental effects to one of the most imperial groups of vertebrates, reptiles. Taking a multispecies approach, we used a Before-After-Control-Impact study design to compare reptile abundance on the highway before and after mitigation at an Impact site and a Control site from 1 May to 31 August in 2012 and 2013. During this time, radio telemetry, wildlife cameras, and an automated PIT-tag reading system were used to monitor reptile movements and use of ecopassages. Additionally, a willingness to utilize experiment was conducted to quantify turtle behavioral responses to ecopassages. We found no difference in abundance of turtles on the road between the un-mitigated and mitigated highways, and an increase in the percentage of both snakes and turtles detected dead on the road post-mitigation, suggesting that the fencing was not effective. Although ecopassages were used by reptiles, the number of crossings through ecopassages was lower than road-surface crossings. Furthermore, turtle willingness to use ecopassages was lower than that reported in previous arena studies, suggesting that effectiveness of ecopassages may be compromised when alternative crossing options are available (e.g., through holes in exclusion structures. Our rigorous evaluation of reptile roadway mitigation demonstrated that when exclusion structures fail, the effectiveness of population connectivity structures is compromised. Our project emphasizes the need to design mitigation measures with the biology and behavior of the target species in mind, to implement mitigation designs in a rigorous fashion, and quantitatively

  15. INTEGRATED REPORTING AS A BASIS FOR ESSENTIALITY INCREASING OF ACCOUNTING INFORMATION

    Directory of Open Access Journals (Sweden)

    Rybyantseva M. S.

    2016-06-01

    Full Text Available Basic information files that revealing external users with information about the organization are the accounting financial statements. Reforms of the national accounting led to reduction of reporting forms informativeness and removal of transcripts. There was an obvious need for the formation of statements that reveals a wider range of indicators. Thus, integrated reporting can be such information array. Integrated reporting is the accounting tool, the information array about the organization. Integrated reporting includes such positions, as: a set of indicators characterized the economic, social and environmental aspects of the entity; the corporate management system that allows interested users to track the process of entity’s value creation and to form an opinion about its economic value. This type of reporting will be able to shape in accordance with the proposed methodological document "Rules of integrated reporting formation". This document assumes the following structure of integrated reporting: relevant information about the organization, historical information, environmental information, social information, innovation, internal control system, decoding of the financial statements, analysis of financial condition and financial results

  16. Treatment Integrity Assessment of a Daily Report Card Intervention: A Preliminary Evaluation of Two Methods and Frequencies

    Science.gov (United States)

    Sanetti, Lisa M. Hagermoser; Chafouleas, Sandra M.; O'Keeffe, Breda V.; Kilgus, Stephen P.

    2013-01-01

    Although intuitively appealing, teacher self-report of treatment integrity is not currently recommended as a method for collecting treatment integrity data. Education researchers have not, however, evaluated features of a treatment integrity self-reporting system that may facilitate accurate self-report. In this preliminary investigation, four…

  17. Gore-Mbeki Binational Commission integrated housing program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report documents the work done under Grant DE-FG36-97GO10209, Innovative Renewable Energy Technology Transfer Program. PEER Consultants, PC, and its subcontractor, PEER Africa (Pty.) Ltd., received an $88,000.00 grant to plan and build two energy efficient homes in the black township of Gugulethu in Cape Town, South Africa. These demonstration homes were given to the people of South Africa as a gesture of goodwill by the US government as part of the Gore-Mbeki Binational Commission (BNC) agreements and cooperation. The BNC is the term used to describe the agreement to work together by the US and the South African governments for economic development of South Africa in the areas of energy, commerce, agriculture, housing, and transportation. The BNC was formed in 1995. This project under the auspices of the BNC started in September 1996. The DOE-funded portion was performed between January 11, 1997 and February 28, 1997.

  18. 40 CFR 13.25 - Standards for compromise.

    Science.gov (United States)

    2010-07-01

    ... enforced collection proceedings. In evaluating the acceptability of the offer, the Administrator may... under State and Federal law in determining the Government's ability to enforce collection. (2) Municipal... proceedings. (b) EPA may compromise a claim, or recommend acceptance of a compromise to DOJ, where there...

  19. 26 CFR 300.3 - Offer to compromise fee.

    Science.gov (United States)

    2010-04-01

    ... taxpayer if the offer is accepted, rejected, withdrawn, or returned as nonprocessable after acceptance for... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Offer to compromise fee. 300.3 Section 300.3... ADMINISTRATION USER FEES § 300.3 Offer to compromise fee. (a) Applicability. This section applies to...

  20. Macro-meso-microsystems integration in LTCC : LDRD report.

    Energy Technology Data Exchange (ETDEWEB)

    De Smet, Dennis J.; Nordquist, Christopher Daniel; Turner, Timothy Shawn; Rohrer, Brandon Robinson; Walker, Charles A.; Ho, Clifford K..; Patel, Kamlesh D.; Okandan, Murat; Rohde, Steven Barney; Wroblewski, Brian D.; Pfeifer, Kent Bryant; Peterson, Kenneth Allen; Buerger, Stephen P.

    2007-03-01

    Low Temperature Cofired Ceramic (LTCC) has proven to be an enabling medium for microsystem technologies, because of its desirable electrical, physical, and chemical properties coupled with its capability for rapid prototyping and scalable manufacturing of components. LTCC is viewed as an extension of hybrid microcircuits, and in that function it enables development, testing, and deployment of silicon microsystems. However, its versatility has allowed it to succeed as a microsystem medium in its own right, with applications in non-microelectronic meso-scale devices and in a range of sensor devices. Applications include silicon microfluidic ''chip-and-wire'' systems and fluid grid array (FGA)/microfluidic multichip modules using embedded channels in LTCC, and cofired electro-mechanical systems with moving parts. Both the microfluidic and mechanical system applications are enabled by sacrificial volume materials (SVM), which serve to create and maintain cavities and separation gaps during the lamination and cofiring process. SVMs consisting of thermally fugitive or partially inert materials are easily incorporated. Recognizing the premium on devices that are cofired rather than assembled, we report on functional-as-released and functional-as-fired moving parts. Additional applications for cofired transparent windows, some as small as an optical fiber, are also described. The applications described help pave the way for widespread application of LTCC to biomedical, control, analysis, characterization, and radio frequency (RF) functions for macro-meso-microsystems.

  1. Truss-Integrated Thermoformed Ductwork Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Steven Winter; Dianne Griffiths; Ravi Gorthala

    2007-08-30

    This report summarizes a multi-year research effort to develop a leak-free duct system that can be readily installed within the thermal envelope. There are numerous efforts underway to improve duct system efficiency. Most of these involve modifications to current technology such as air sealing techniques like mastic and aeroseal, snap together duct connections, and greater levels of insulation. This project sought to make a more significant stride forward by introducing a duct system of a material that can be more readily sealed and can exhibit lower friction losses. The research focused on the use of smooth internal surface, low friction plastic ducts that could be easily installed with very low air leakage. The initial system concept that was proposed and researched in Phase I focused on the use of thermoformed plastic ducts installed in a recessed roof truss underneath the attic insulation. A bench top thermoformed system was developed and tested during Phase I of the project. In Phase II, a first generation duct system utilizing a resin impregnated fiberglass duct product was designed and specified. The system was installed and tested in an Atlanta area home. Following this installation research and correspondence with code officials was undertaken to alleviate the continued concern over the code acceptance of plastic ducts in above ground applications. A Committee Interpretation response was received from the International Code Council (ICC) stating that plastic ducts were allowed, but must be manufactured from materials complying with Class 0 or Class 1 rating. With assurance of code acceptance, a plastic duct system using rotomolded high density polyethylene ducts that had passed the material test requirements by impregnating the material with a fire retardant during the molding process was installed in the basement of a new ranch-style home in Madison, WI. A series of measurements to evaluate the performance benefits relative to a similar control house with

  2. Tank 241-C-106 sluicing project W-320 integrity assessment report

    Energy Technology Data Exchange (ETDEWEB)

    Symons, G.A., Fluor Daniel Hanford

    1997-02-11

    This Integrity Assessment Report is prepared by ICF Kaiser Hanford Co. (ICFKH) for Westinqhouse Hanford Company (WHC), operations contractor and the Department of Energy (DOE), the system owner. It is a revision of the original report dated 10/26/94 (ICFKH Transmittal TR-W-320-295). The original project scope has been modified, necessitating with WAC-173-303-640.

  3. Report: Recommendation to Strengthen Management Integrity Processes Affecting Recovery Act Activities

    Science.gov (United States)

    Report #09-X-0145, April 27, 2009. The EPA OIG has completed a review of the Agency’s Fiscal Year (FY) 2009 Management Integrity guidance for reporting on internal control reviews and preparing the annual assurance letters sent to the Administrator.

  4. INTEGRATION OF FINANCIAL AND NON-FINANCIAL REPORTS UNDER MANAGEMENT CONDITIONS

    Directory of Open Access Journals (Sweden)

    Mihail PRODANCIUK

    2013-02-01

    Full Text Available The paper presents the assessment of the development of integrated reports overseas and describes the stages of establishment of such a system. The form and structure of corporate reporting is developed, and is differentiated, reflecting the integrated information regarding aspects of financial and non-financial activity: statistical indicators, economical, financial and social, company strategy, future cash flows, the value of human capital, and the stability of the business model. Goals and objectives of corporate reports are determined, which consist in providing reliable information on all company activities in accordance with strategic objectives and management models. The structure of the integrated report takes into consideration the requirements of the management system, of the legislative bodies and other institutions, and is considered the basis for the development of branch reports models. Its structure will depend on the size of the legal-organizational form and the social value of the company in society. The author of the article suggests three approaches to achieving corporate reports in the section of social responsibility indicators; where each company chooses the form of reporting in accordance with the available categories that depend on the size and strategic policy. The suggested integrated reports are instrumental to the observance of the stable development doctrines and will become a tool that, in the near future, will ensure the company an effective interaction with financial markets and the stakeholders of market relations.

  5. Integration of financial and non-financial reports under management conditions

    Directory of Open Access Journals (Sweden)

    Prodanciuk Mihail

    2013-02-01

    Full Text Available The paper presents the assessment of the development of integrated reports overseas and describes the stages of establishment of such a system. The form and structure of corporate reporting is developed, and is differentiated, reflecting the integrated information regarding aspects of financial and non-financial activity: statistical indicators, economical, financial and social, company strategy, future cash flows, the value of human capital, and the stability of the business model. Goals and objectives of corporate reports are determined, which consist in providing reliable information on all company activities in accordance with strategic objectives and management models.The structure of the integrated report takes into consideration the requirements of the management system, of the legislative bodies and other institutions, and is considered the basis for the development of branch reports models. Its structure will depend on the size of the legal-organizational form and the social value of the company in society. The author of the article suggests three approaches to achieving corporate reports in the section of social responsibility indicators; where each company chooses the form of reporting in accordance with the available categories that depend on the size and strategic policy. The suggested integrated reports are instrumental to the observance of the stable development doctrines and will become a tool that, in the near future, will ensure the company an effective interaction with financial markets and the stakeholders of market relations.

  6. Is essential learning being compromised by austerity?

    Science.gov (United States)

    Glasper, Alan

    Emeritus professor Alan Glasper, from the University of Southampton discusses the recently published Royal College of Nursing survey report that campaigns to raise awareness of the threats to post-qualifying education for nurses.

  7. Auditing Litigation and Claims: Conflicts and the Compromise of Privilege

    Directory of Open Access Journals (Sweden)

    Harleen Kaur

    2013-12-01

    Full Text Available Auditing standards require an auditor to make various enquiries about liabilities in general this may entail consideration of potential litigations and claims that the audited entity may be facing. To perform this part of audit, the auditors will generally seek representation letters from lawyers of the company detailing an estimate prepared by management, confirmed by their lawyers through a representation letter, and then sent directly to the auditors. This paper reviews the implications for the auditing profession of a case that involved auditors seeking such representation letters. The case involves litigation between theWestpac Banking Corporation and 789TEN Pty Ltd. While theWestpac case confirmed the legal position of the auditor in their task of collecting evidence in order to form an opinion in Australia, it highlights a significant anomaly under the law and should place the issue of solicitor’s representation letters as audit evidence firmly on the agenda of policymakers. This issue of the compromise of legal privilege during the conduct of an audit is also not confined to Australia: other common law jurisdictions, such as the UK and the US, have also sought to clarify the position of auditors when issues of the integrity of legal privacy privilege arise.

  8. Informatics in radiology: web-based preliminary reporting system for radiology residents with PACS integration.

    Science.gov (United States)

    O'Connell, Timothy; Chang, Debra

    2012-01-01

    While on call, radiology residents review imaging studies and issue preliminary reports to referring clinicians. In the absence of an integrated reporting system at the training sites of the authors' institution, residents were typing and faxing preliminary reports. To partially automate the on-call resident workflow, a Web-based system for resident reporting was developed by using the free open-source xAMP Web application framework and an open-source DICOM (Digital Imaging and Communications in Medicine) software toolkit, with the goals of reducing errors and lowering barriers to education. This reporting system integrates with the picture archiving and communication system to display a worklist of studies. Patient data are automatically entered in the preliminary report to prevent identification errors and simplify the report creation process. When the final report for a resident's on-call study is available, the reporting system queries the report broker for the final report, and then displays the preliminary report side by side with the final report, thus simplifying the review process and encouraging review of all of the resident's reports. The xAMP Web application framework should be considered for development of radiology department informatics projects owing to its zero cost, minimal hardware requirements, ease of programming, and large support community.

  9. Career Development Strategies as Moderators between Career Compromise and Career Outcomes in Emerging Adults

    Science.gov (United States)

    Creed, Peter A.; Hughes, Trinette

    2013-01-01

    The authors surveyed 130 first-year university students (80% female; mean age 20.5) and assessed (a) the level of career compromise they reported between their ideal and enrolled university programs, (b) their career-related strategies, (c) their perceptions of employability, and (d) their career-related distress. The authors tested a model that…

  10. Career Development Strategies as Moderators between Career Compromise and Career Outcomes in Emerging Adults

    Science.gov (United States)

    Creed, Peter A.; Hughes, Trinette

    2013-01-01

    The authors surveyed 130 first-year university students (80% female; mean age 20.5) and assessed (a) the level of career compromise they reported between their ideal and enrolled university programs, (b) their career-related strategies, (c) their perceptions of employability, and (d) their career-related distress. The authors tested a model that…

  11. Greenhouse Gas Emissions Reporting through Integrated Business Solutions

    Science.gov (United States)

    Smith, D.

    2010-12-01

    Given the risks posed by global climate change, it is important that society as a whole responds in order to reduce the emission of greenhouse gas (GHG) into the atmosphere. Whether you are an environmentalist, a small-to-medium business owner, or a corporate risk manager - the need to act is now in order to reduce future environmental damage. While this sounds overwhelming, it’s really quite simple. Carbon Management is the process of understanding where your commercial activities generate GHG emissions, so that you can reduce those emissions in a planned, financially responsible way. Specifically, governments have the capacity to lead in this area and reduce these costs throughout their cities. Village Green Global develops and manages demonstration projects for the government that act as exemplar models to assist in gathering verifiable GHG reporting within selected regions and cities. This model highlights opportunities for the capture of conservation and energy credit commodities for local financial markets to use in global trading. Information gathered will prepare government for the ongoing changing global requirements and mitigate risk of unnecessary market exposure and cost; allow government to take a measured, responsible approach to its environmental responsibilities; reduce operational costs, improving the government’s asset utilization and more effectively streamlining its operations; and establish the government as responsible and proactive due to its creative approach to environmental challenges. Village Green Global’s government partnership model aims to deliver new jobs and technologies in the emerging “green economy;” a linkage to education at both at College and University levels, then assisting industry and community needs; and the involvement of industry leaders ensures training is targeted to job creation and local capacity building opportunities, in turn creating new skills and career pathways for the displaced workforce from the

  12. Development of efficient, integrated cellulosic biorefineries : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Teh, Kwee-Yan; Hecht, Ethan S.; Shaddix, Christopher R.; Buffleben, George M.; Dibble, Dean C.; Lutz, Andrew E.

    2010-09-01

    supplied by a recent report from the National Research Council (NRC). The thermochemical system analysis revealed that most of the system inefficiency is associated with the gasification process and subsequent tar reforming step. For the biochemical process, the steam generation from residue combustion, providing the requisite heating for the conventional pretreatment and alcohol distillation processes, was shown to dominate the exergy loss. An overall energy balance with different potential distillation energy requirements shows that as much as 30% of the biomass energy content may be available in the future as a feedstock for thermochemical production of liquid fuels.

  13. Power, Avionics and Software - Phase 1.0:. [Subsystem Integration Test Report

    Science.gov (United States)

    Ivancic, William D.; Sands, Obed S.; Bakula, Casey J.; Oldham, Daniel R.; Wright, Ted; Bradish, Martin A.; Klebau, Joseph M.

    2014-01-01

    This report describes Power, Avionics and Software (PAS) 1.0 subsystem integration testing and test results that occurred in August and September of 2013. This report covers the capabilities of each PAS assembly to meet integration test objectives for non-safety critical, non-flight, non-human-rated hardware and software development. This test report is the outcome of the first integration of the PAS subsystem and is meant to provide data for subsequent designs, development and testing of the future PAS subsystems. The two main objectives were to assess the ability of the PAS assemblies to exchange messages and to perform audio testing of both inbound and outbound channels. This report describes each test performed, defines the test, the data, and provides conclusions and recommendations.

  14. Integrated Reporting in OMXS30 companies - An Analysis of Human Capital Disclosures

    OpenAIRE

    Schulz, Nathalie; Burenius, Frida

    2016-01-01

    Background and Problem: Sustainability reporting is a growing interest in today’s organizations and it is essential to report on non-financial matters. Many of the existing frameworks have been criticized for being used only of symbolical reasons which is why the concept of integrated reporting and the framework have been developed. One of the cornerstones in the framework is human capital which is one of the most valuable assets in an organization. Traditionally, employ...

  15. Integral glass encapsulation for solar arrays. Quarterly progress report No. 13

    Energy Technology Data Exchange (ETDEWEB)

    Landis, Geoffrey A.

    1980-03-01

    Progress on the development of electrostatic bonding as a method of integrally encapsulating silicon solar cells in glass is reported. Efforts for the current phase of this program are to continue to demonstrate process uniformity of encapsulation by electrostatic bonding. An additional goal for this program is to develop preformed contacts as a method of integrating cell processing into the encapsulation procedure, resulting in a low-cost module assembly technique.

  16. College Student-Athlete Wellness: An Integrative Outreach Model

    Science.gov (United States)

    Beauchemin, James

    2014-01-01

    College student-athletes face unique stressors that can contribute to compromised well-being. Additionally, there are a variety of barriers that prevent student-athletes from accessing mental health supports. This study used self-report questionnaires and qualitative interviews to examine the impact of an integrative outreach model that…

  17. Iatrogenic Digital Compromise with Tubular Dressings

    Directory of Open Access Journals (Sweden)

    Corre, Kenneth A

    2009-08-01

    Full Text Available Objective: This case report describes a digit amputation resulting from an improperly applied tubular dressing. The safe application of digital tubular dressings, and the rationale behind it, is detailed to raise emergency physician (EP awareness.Methods: We present a case report of a recent iatrogenic-induced digit ischemia caused by improperly applied tube gauze. We review the literature on the subject and the likely sources of poor outcomes presented. The proper application of tubular gauze dressings is then outlined.Conclusion: EPs and emergency department personnel must be educated on the safe application of tubular gauze dressings to avoid dire outcomes associated with improper applications.[WestJEM. 2009;10:190-192.

  18. Compromised data from social media to big data

    CERN Document Server

    Redden, Joanna; Langlois, Ganaele

    2015-01-01

    There has been a data rush in the past decade brought about by online communication and, in particular, social media (Facebook, Twitter, Youtube, among others), which promises a new age of digital enlightenment. But social data is compromised: it is being seized by specific economic interests, it leads to a fundamental shift in the relationship between research and the public good, and it fosters new forms of control and surveillance. Compromised Data: From Social Media to Big Data explores how we perform critical research within a compromised social data framework. The expert, international l

  19. Integration

    DEFF Research Database (Denmark)

    Emerek, Ruth

    2004-01-01

    Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration......Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration...

  20. Post-fine-needle aspiration biopsy communication and the integrated and standardized cytopathology report.

    Science.gov (United States)

    Pitman, Martha B; Black-Schaffer, W Stephen

    2017-06-01

    Communication between cytopathologists and patients and their care team is a critical component of accurate and timely patient management. The most important single means of communication for the cytopathologist is through the cytopathology report. Implementation of standardized terminology schemes and structured, templated reporting facilitates the ability of the cytopathologist to provide a comprehensive and integrated report. Cytopathology has been among the pathology subspecialties that have led the way in developing standardized reporting, beginning with the 1954 Papanicolaou classification scheme for cervical-vaginal cytology and continuing through the Bethesda systems for gynecological cytology and several nongynecological cytology systems. The effective reporting of cytopathology necessarily becomes more complex as it addresses increasingly sophisticated management options, requiring the integration of information from a broader range of sources. In addition to the complexity of information inputs, a wider spectrum of consumers of these reports is emerging, from patients themselves to primary care providers to subspecialized disease management experts. Both these factors require that the reporting cytopathologist provide the integration and interpretation necessary to translate diverse forms of information into meaningful and actionable reports that will inform the care team while enabling the patient to meaningfully participate in his or her own care. To achieve such broad and focused communications will require first the development of standardized and integrated reports and ultimately the involvement of cytopathologists in the development of the clinical informatics needed to treat all these items of information as structured data elements with flexible reporting operators to address the full range of patient and patient care needs. Cancer Cytopathol 2017;125(6 suppl):486-93. © 2017 American Cancer Society. © 2017 American Cancer Society.

  1. Large-scale building integrated photovoltaics field trial. First technical report - installation phase

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This report summarises the results of the first eighteen months of the Large-Scale Building Integrated Photovoltaic Field Trial focussing on technical aspects. The project aims included increasing awareness and application of the technology, raising the UK capabilities in application of the technology, and assessing the potential for building integrated photovoltaics (BIPV). Details are given of technology choices; project organisation, cost, and status; and the evaluation criteria. Installations of BIPV described include University buildings, commercial centres, and a sports stadium, wildlife park, church hall, and district council building. Lessons learnt are discussed, and a further report covering monitoring aspects is planned.

  2. Self-reported patient psychosocial needs in integrated primary health care: A role for social work in interdisciplinary teams.

    Science.gov (United States)

    Craig, Shelley; Frankford, Rachel; Allan, Kate; Williams, Charmaine; Schwartz, Celia; Yaworski, Andrea; Janz, Gwen; Malek-Saniee, Sara

    2016-01-01

    Despite being identified as significant determinants of health, depression and anxiety continue to be underdiagnosed and undertreated in primary care settings. This study examined the psychosocial health needs of patients at four urban interdisciplinary primary health teams. Quantitative analysis revealed that nearly 80% of patients reported anxiety and/or depression. Self-reported anxiety and depression was correlated with poor social relationships, compromised health status and underdeveloped problem-solving skills. These findings suggest that social workers have a vital role to play within interdisciplinary primary health teams in the amelioration of factors associated with anxiety and depression.

  3. Value Creation Reporting: Answering the Question ‘Value to Whom’ according to the International Integrated Reporting Framework

    Directory of Open Access Journals (Sweden)

    Soner Gokten

    2017-04-01

    Full Text Available Value Creation Reporting: Answering the Question ‘Value to Whom’ according to the International Integrated Reporting Framework The principal function of integrated reporting is the reporting of value and this phenomenon seems the most philosophical part of the International Framework. This paper discusses what the value concept refers to in the Framework: Value to investors, value to society or value to present and future generations? In this sense, we try to answer this question by highlighting the dynamics of capital formations according to interrelations between capitals and demonstrating the value creation process in the short, medium, and longer term. We show that (1 „profit” is the result of short term value creation, which indicates the „value to value chain stakeholders”, (2 „expected fair value of equity” represents the „value to investors” and (3 „longer term value” represents the „value to society” according to the International Framework. Additionally, we touch on the inadequacies of the current Framework and suggest future research opportunities within the scope of value creation reporting. To our knowledge, this study is the first to provide a detailed framework on the dynamics of capitals usage and it attempts to show the intersection of accounting and finance in terms of value creation reporting.

  4. 45 CFR 30.22 - Bases for compromise.

    Science.gov (United States)

    2010-10-01

    ... income; (iii) Inheritance prospects; (iv) The possibility that assets have been concealed or improperly... other property will bring at a forced sale. (ii) A compromise effected under this section should be...

  5. 41 CFR 105-55.020 - Bases for compromise.

    Science.gov (United States)

    2010-07-01

    ... following: (1) Age and health of the debtor. (2) Present and potential income. (3) Inheritance prospects. (4... sale in determining the Government's ability to enforce collection. A compromise effected under...

  6. Annual Report of the Integrated Status and Effectiveness Monitoring Program: Fiscal Year 2008

    Energy Technology Data Exchange (ETDEWEB)

    Terraqua, Inc. (Wauconda, WA)

    2009-07-20

    This document was created as an annual report detailing the accomplishments of the Integrated Status and Effectiveness Monitoring Program (ISEMP) in the Upper Columbia Basin in fiscal year 2008. The report consists of sub-chapters that reflect the various components of the program. Chapter 1 presents a report on programmatic coordination and accomplishments, and Chapters 2 through 4 provide a review of how ISEMP has progressed during the 2008 fiscal year in each of the pilot project subbasins: the John Day (Chapter 2), Wenatchee/Entiat (Chapter 3) and Salmon River (Chapter 4). Chapter 5 presents a report on the data management accomplishments in 2008.

  7. Independent peer review panel report on the integrated nonthermal treatment systems study and the comparison of integrated thermal and integrated nonthermal treatment systems for mixed low level waste

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    The US Department of Energy`s (DOE) Office of Environmental Management (EM) Office of Science and Technology (OST) has conducted studies of integrated thermal treatment systems and integrated nonthermal treatment systems (INTS) for treating contact handled, alpha and non-alpha mixed low level radioactive waste (MLLW). The MLLW in the DOE complex consists of a wide variety of organic and inorganic solids and liquids contaminated with radioactive substances. Treatment systems are needed to destroy organic material and stabilize residues prior to land disposal. In May 1996 the Deputy Assistant Secretary for OST appointed an Independent Peer Review Panel to: (1) review and comment on the INTS Study; (2) make recommendations on the most promising thermal and nonthermal treatment systems; (3) make recommendations on research and development necessary to prove the performance of nonthermal and thermal technologies; and (4) review and comment on the preliminary draft of the ITTS/INTS Comparison Report. This report presents the primary conclusions and recommendations based on the review of the INTS study and the comparison report. System selection, overviews, comparisons, cost estimations and sensitivity analyses, and recommended R and D engineering needs are then described and discussed.

  8. [Integrity].

    Science.gov (United States)

    Gómez Rodríguez, Rafael Ángel

    2014-01-01

    To say that someone possesses integrity is to claim that that person is almost predictable about responses to specific situations, that he or she can prudentially judge and to act correctly. There is a closed interrelationship between integrity and autonomy, and the autonomy rests on the deeper moral claim of all humans to integrity of the person. Integrity has two senses of significance for medical ethic: one sense refers to the integrity of the person in the bodily, psychosocial and intellectual elements; and in the second sense, the integrity is the virtue. Another facet of integrity of the person is la integrity of values we cherish and espouse. The physician must be a person of integrity if the integrity of the patient is to be safeguarded. The autonomy has reduced the violations in the past, but the character and virtues of the physician are the ultimate safeguard of autonomy of patient. A field very important in medicine is the scientific research. It is the character of the investigator that determines the moral quality of research. The problem arises when legitimate self-interests are replaced by selfish, particularly when human subjects are involved. The final safeguard of moral quality of research is the character and conscience of the investigator. Teaching must be relevant in the scientific field, but the most effective way to teach virtue ethics is through the example of the a respected scientist.

  9. A Commentary on "Integrated Reporting: A Review of Developments and Their Implications for the Accounting Curriculum"

    Science.gov (United States)

    Correa Ruiz, Carmen

    2013-01-01

    In this commentary, Correa Ruiz notes that from his analysis, Owen (2013) identified the essential elements to be included in a modern professional accounting curriculum, described how Association of Chartered Certified Accountants (ACCA) has embedded "Integrated Reporting" in its curriculum, and discussed future curriculum development,…

  10. Integrated Reporting: A Review of Developments and Their Implications for the Accounting Curriculum

    Science.gov (United States)

    Owen, Gareth

    2013-01-01

    Integrated reporting (IR) is a major development in a number of sustainability-related accounting initiatives and, if widely adopted, will require significant developments in professional and university accounting curricula. These will include: a strategic rather than operational or transactional focus; longer- rather than short-term outlook;…

  11. Preliminary design report for the K basins integrated water treatment system

    Energy Technology Data Exchange (ETDEWEB)

    Pauly, T.R., Westinghouse Hanford

    1996-08-12

    This Preliminary Design Report (PDR) provides a revised concept for the K Basins Integrated Water Treatment Systems (IWTS). This PDR incorporates the 11 recommendations made in a May 1996 Value Engineering session into the Conceptual Design, and provides new flow diagrams, hazard category assessment, cost estimate, and schedule for the IWTS Subproject.

  12. 2013-14 Integrated Postsecondary Education Data System (IPEDS) Methodology Report. NCES 2014-067

    Science.gov (United States)

    Ginder, Scott A.; Kelly-Reid, Janice E.; Mann, Farrah B.

    2014-01-01

    This report describes the universe, methods, and editing procedures used in the 2013-14 Integrated Postsecondary Education Data System (IPEDS) data collection. IPEDS data consist of basic statistics on postsecondary institutions regarding tuition and fees, number and types of degrees and certificates conferred, number of students enrolled, number…

  13. 2012-13 Integrated Postsecondary Education Data System (IPEDS) Methodology Report. NCES 2013-293

    Science.gov (United States)

    Ginder, Scott A.; Kelly-Reid, Janice E.

    2013-01-01

    This report describes the universe, methods, and editing procedures used in the 2012-13 Integrated Postsecondary Education Data System (IPEDS) data collection. IPEDS data consist of basic statistics on postsecondary institutions regarding tuition and fees, number and types of degrees and certificates conferred, number of students enrolled, number…

  14. 2011-12 Integrated Postsecondary Education Data System (IPEDS) Methodology Report. NCES 2012-293

    Science.gov (United States)

    Knapp, Laura G.; Kelly-Reid, Janice E.; Ginder, Scott A.

    2012-01-01

    This report describes the universe, methods, and editing procedures used in the 2011-12 Integrated Postsecondary Education Data System (IPEDS) data collection. IPEDS data consist of basic statistics on postsecondary institutions regarding tuition and fees, number and types of degrees and certificates conferred, number of students enrolled, number…

  15. Report of the Integrated Program Planning Activity for the DOE Fusion Energy Sciences Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-12-01

    This report of the Integrated Program Planning Activity (IPPA) has been prepared in response to a recommendation by the Secretary of Energy Advisory Board that, ''Given the complex nature of the fusion effort, an integrated program planning process is an absolute necessity.'' We, therefore, undertook this activity in order to integrate the various elements of the program, to improve communication and performance accountability across the program, and to show the inter-connectedness and inter-dependency of the diverse parts of the national fusion energy sciences program. This report is based on the September 1999 Fusion Energy Sciences Advisory Committee's (FESAC) report ''Priorities and Balance within the Fusion Energy Sciences Program''. In its December 5,2000, letter to the Director of the Office of Science, the FESAC has reaffirmed the validity of the September 1999 report and stated that the IPPA presents a framework and process to guide the achievement of the 5-year goals listed in the 1999 report. The National Research Council's (NRC) Fusion Assessment Committee draft final report ''An Assessment of the Department of Energy's Office of Fusion Energy Sciences Program'', reviewing the quality of the science in the program, was made available after the IPPA report had been completed. The IPPA report is, nevertheless, consistent with the recommendations in the NRC report. In addition to program goals and the related 5-year, 10-year, and 15-year objectives, this report elaborates on the scientific issues associated with each of these objectives. The report also makes clear the relationships among the various program elements, and cites these relationships as the reason why integrated program planning is essential. In particular, while focusing on the science conducted by the program, the report addresses the important balances between the science and energy goals of the program, between the

  16. Progress report 13 for April 1979-August 1979 and proceedings of the 13th project integration meeting

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    This report describes progress made by the Low-Cost Solar Array Project during the period April through August 1979. It includes reports on project analysis and integration; technology development in silicon material, large-area sheet silicon, and encapsulation; production process and equipment development; engineering and operations, and a discussion of the steps taken to integrate these efforts. It includes a report on, and copies of viewgraphs presented at the Project Integration Meeting held August 22-23, 1979.

  17. The evaluation of integrating physical restraint report and care record system.

    Science.gov (United States)

    Hou, I-Ching; Chen, Jimmy; Lin, Fan-Lian; Yu, Hui-Zu; Huang, Si-Fen; Huang, Yue-Jiao

    2013-01-01

    Physical restraint is the nursing intervention to protect patient safety in the hospital. Nurses should monitor and charting during the physical restraint period. Physical restraint is also the measurement of Taiwan clinical performance indicator. The traditional physical restraint quality measurement depends on the nurses' report. Lacking of integrating of report and nurses' care record induces the low report rate. In 2007, we developed the integrating physical restraint report and care record system to facilitate the report process in 2300-bed medical center in northern Taiwan. We evaluated the system with two methods after system implemented for one year. The results show it significantly increased the reporting rate from before (0.77%) to after (1.5%) and had no significance difference with the average reporting rate in Taiwan (P>0.05). Most nurses felt nature to satisfy on the system usefulness (81%) and preferred to use system then use paper form record (83.1%). Almost every nurse had correct cognitions on report physical restrain event when it occurred to patients. The system seemed to be successful implemented and helpful for the quality measurement management.

  18. Enhanced CRISPR/Cas9-mediated biallelic genome targeting with dual surrogate reporter-integrated donors.

    Science.gov (United States)

    Wu, Yun; Xu, Kun; Ren, Chonghua; Li, Xinyi; Lv, Huijiao; Han, Furong; Wei, Zehui; Wang, Xin; Zhang, Zhiying

    2017-03-01

    The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system has recently emerged as a simple, yet powerful genome engineering tool, which has been widely used for genome modification in various organisms and cell types. However, screening biallelic genome-modified cells is often time-consuming and technically challenging. In this study, we incorporated two different surrogate reporter cassettes into paired donor plasmids, which were used as both the surrogate reporters and the knock-in donors. By applying our dual surrogate reporter-integrated donor system, we demonstrate high frequency of CRISPR/Cas9-mediated biallelic genome integration in both human HEK293T and porcine PK15 cells (34.09% and 18.18%, respectively). Our work provides a powerful genetic tool for assisting the selection and enrichment of cells with targeted biallelic genome modification. © 2017 Federation of European Biochemical Societies.

  19. KEY PERFORMANCE INDICATORS. A CASE STUDY ON THE INTEGRATED REPORTS OF AN IT COMPANY

    Directory of Open Access Journals (Sweden)

    GORGAN CĂTĂLINA

    2014-06-01

    Full Text Available Our analysis relies on the 2011 integrated report published by SAP, a European IT company included in the International Integrated Reporting Committee (IIRC Pilot Programme Business Network. The research methodology used is the analysis of the content as we search for a number of selected characteristics in the report and also for a set of key performance indicators (KPI. We use as references the guide provided by DVFA (Society of Investment Professionals in Germany and EFFAS (European Federation of Financial Analysts Societies – EFFAS (2010 for the software industry. The aim of our study is to analyse the way in which an IT company applies the guidelines recognised by the European Commission to identify and communicate the material nonfinancial information, in order to assess the organization’s abilities to create value on a short, medium and long term.

  20. The administration of probiotics and synbiotics in immune compromised adults: is it safe?

    Science.gov (United States)

    Van den Nieuwboer, M; Brummer, R J; Guarner, F; Morelli, L; Cabana, M; Claasen, E

    2015-03-01

    This study aimed to systematically evaluate safety of probiotics and synbiotics in immune compromised adults (≥18 years). Safety was analysed using the Common Terminology Clinical Adverse Events (CTCAE version 4.0) classification, thereby providing an update on previous reports using the most recent available clinical data (2008-2013). Safety aspects are represented and related to number of participants per probiotic strain/culture, study duration, dosage, clinical condition and selected afflictions. Analysis of 57 clinical studies indicates that probiotic and/or synbiotic administration in immune compromised adults is safe with regard to the current evaluated probiotic strains, dosages and duration. Individuals were considered immune compromised if HIV-infected, critically ill, underwent surgery or had an organ- or an autoimmune disease. There were no major safety concerns in the study, as none of the serious adverse events (AE)s were related, or suspected to be related, to the probiotic or synbiotic product and the study products were well tolerated. Overall, AEs occurred less frequent in immune compromised subjects receiving probiotics and/or synbiotics compared to the control group. In addition, the results demonstrated a flaw in precise reporting and classification of AE in most studies. Furthermore, generalisability of conclusions are greatly limited by the inconsistent, imprecise and potentially incomplete reporting as well as the variation in probiotic strains, dosages, administration regimes, study populations and reported outcomes. We argue that standardised reporting on adverse events (CTCAE) in 'food' studies should be obligatory, thereby improving reliability of data and re-enforcing the safety profile of probiotics.

  1. A brief report: Yale Research Symposium on Complementary and Integrative Medicine.

    Science.gov (United States)

    Ali, Ather; Vitulano, Lawrence A

    2010-09-01

    The 2010 Yale Research Symposium on Complementary and Integrative Medicine highlighted original research in related areas by Yale faculty and provided a forum to discuss and debate issues of evidence and plausibility. In this brief report, we describe selected presentations on such diverse foci as nutritional influences on cancer, acupuncture for low back pain, protein intake's effects on bone consumption, Chinese herb-derived adjuvant chemotherapy, and the relationship between anger and cardiac arrhythmia. This symposium demonstrated that rigorous research methods are being used to study unconventional therapies and that an integrative medicine approach requires a solid scientific foundation.

  2. Buried waste integrated demonstration fiscal year 1992 close-out report

    Energy Technology Data Exchange (ETDEWEB)

    Cannon, P.G.; Kostelnik, K.M.; Owens, K.J.

    1993-02-01

    The mission of the Buried Waste Integrated Demonstration Program (BWID) is to support the development and demonstration of a suite of technologies that when integrated with commercially-available baseline technologies form a comprehensive remediation system for the effective and efficient remediation of buried waste disposed of throughout the US Department of Energy complex. To accomplish this mission of identifying technological solutions for remediation deficiencies, the Office of Technology Development initiated the BWID at the Idaho National Engineering Laboratory in fiscal year (FY)-91. This report summarizes the activities of the BWID Program during FY-92.

  3. 10 CFR 905.10 - Who must comply with the integrated resource planning and reporting regulations in this subpart?

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Who must comply with the integrated resource planning and reporting regulations in this subpart? 905.10 Section 905.10 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Integrated Resource Planning § 905.10 Who must comply with the integrated...

  4. Compromising positions: emergent neo-Fordisms and embedded gender contracts.

    Science.gov (United States)

    Gottfried, H

    2000-06-01

    This paper adopts a regulation framework to chart the emergence of neo-Fordism as a flexible accumulation regime and mode of social regulation. Neo-Fordism relies on old Fordist principles as well as incorporating new models of emergent post-Fordisms; old and new social relationships, in their particular combination, specify the trajectory of national variants. I argue that Fordist bargains institutionalized the terms of a compromise between labour, capital and the state. These bargains embedded a male-breadwinner gender contract compromising women's positions and standardizing employment contracts around the needs, interests and authority of men. A focus on compromises and contracts makes visible the differentiated gender effects of work transformation in each country.

  5. Alchemy or Science? Compromising Archaeology in the Deep Sea

    Science.gov (United States)

    Adams, Jonathan

    2007-06-01

    In the torrid debate between archaeology and treasure hunting, compromise is often suggested as the pragmatic solution, especially for archaeology carried out either in deep water or beyond the constraints that commonly regulate such activities in territorial seas. Both the wisdom and the need for such compromise have even been advocated by some archaeologists, particularly in forums such as the internet and conferences. This paper argues that such a compromise is impossible, not in order to fuel confrontation but simply because of the nature of any academic discipline. We can define what archaeology is in terms of its aims, theories, methods and ethics, so combining it with an activity founded on opposing principles must transform it into something else. The way forward for archaeology in the deep sea does not lie in a contradictory realignment of archaeology’s goals but in collaborative research designed to mesh with emerging national and regional research and management plans.

  6. U.S. Department of Energy integrated manufacturing & processing predoctoral fellowships. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Petrochenkov, Margaret

    2003-03-31

    The objective of this program was threefold: to create a pool of PhDs trained in the integrated approach to manufacturing and processing, to promote academic interest in the field, and to attract talented professionals to this challenging area of engineering. It was anticipated that the program would result in the creation of new manufacturing methods that would contribute to improved energy efficiency, to better utilization of scarce resources, and to less degradation of the environment. Emphasis in the competition was on integrated systems of manufacturing and the integration of product design with manufacturing processes. Research addressed such related areas as aspects of unit operations, tooling and equipment, intelligent sensors, and manufacturing systems as they related to product design. This is the final report to close out the contract.

  7. A pilot study for the integration of cytometry reports in digital cytology telemedicine applications

    Directory of Open Access Journals (Sweden)

    Daniele Giansanti

    2010-06-01

    Full Text Available Up to date, tele-pathology in the three different forms of application, "dynamic", "static" and "virtual microscopy" has been mainly based on tele-hystology remote consulting. Today the diffusion of specialized WAN connections is guiding the research of new applications of tele-pathology. A specific analysis has been conducted, focused on digital cytology, in the biomedical laboratory of Sant'Andrea Hospital to investigate the technologies potentially useful to integrate in the LAN/WAN for telemedicine applications. Among the possible tools useful to be integrated in the LAN/WAN for telemedicine applications, the cytometry equipment available in the technical unity of cytometry has been considered important. The study finally provides a proposal for a tele-consulting architecture for the integration of cytometry reports both in the hospital LAN and the WAN for possible cooperative diagnosis and second opinion support.

  8. A pilot study for the integration of cytometry reports in digital cytology telemedicine applications.

    Science.gov (United States)

    Giansanti, Daniele; Cerroni, Fabio; Amodeo, Rachele; Filoni, Marco; Giovagnoli, Maria Rosaria

    2010-01-01

    Up to date, tele-pathology in the three different forms of application, "dynamic", "static" and "virtual microscopy" has been mainly based on tele-hystology remote consulting. Today the diffusion of specialized WAN connections is guiding the research of new applications of tele-pathology. A specific analysis has been conducted, focused on digital cytology, in the biomedical laboratory of Sant'Andrea Hospital to investigate the technologies potentially useful to integrate in the LAN/WAN for telemedicine applications. Among the possible tools useful to be integrated in the LAN/WAN for telemedicine applications, the cytometry equipment available in the technical unity of cytometry has been considered important. The study finally provides a proposal for a tele-consulting architecture for the integration of cytometry reports both in the hospital LAN and the WAN for possible cooperative diagnosis and second opinion support.

  9. Dental implants in bilateral bifid canal and compromised interocclusal space using cone beam computerized tomography

    Science.gov (United States)

    Ahmed, Nizar; Arunachalam, Lalitha Tanjore; Jacob, Caroline Annette; Kumar, Suresh Anand

    2016-01-01

    Knowledge of various anatomic landmarks is pivotal for important success. Bifid canals pose a challenge and can lead to difficulties while performing implant surgery in the mandible. Bifid canals can be diagnosed with panoramic radiography and more accurately with cone beam computerized tomography (CBCT). This case report details the placement of the implant in a patient with bilateral bifid canal and compromised interocclusal space, which was successfully treated using CBCT. PMID:27433073

  10. Esthetic Rehabilitation of a Severely Compromised Anterior Area: Combined Periodontal and Restorative Approach

    OpenAIRE

    Rachele Censi; Virna Vavassori; Andrea Enrico Borgonovo; Dino Re

    2014-01-01

    The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves a multidisciplinary approach that includes the change of both the morphological aspect of the teeth and the architecture of gum tissues. This clinical report describes a successful interdisciplinary approach for the treatment of an esthetically compromised dentition. In a first phase, the periodontal plastic surgery was performed for root coverage and, in particular, it was decided for the executi...

  11. Physically Compromised and Physically Talented Children in Northeastern Slovenia

    Directory of Open Access Journals (Sweden)

    Planinšec Jurij

    2012-12-01

    Full Text Available The aim of our research was to determine the share of physically compromised and physically talented children in northeastern Slovenia. The sample comprised 621 children aged nine to eleven years, among which there were 316 girls (M=10; SD=0.8 and 305 boys (M=10; SD=0.81. In order to assess their motor skills, seven different tests were used, mostly from Eurofit test battery, which covered explosive power, repetitive power balance, eye–hand coordination, speed of simple movements, whole body coordination, and endurance. The assessment was made for each physical fitness test separately. The cut-off points for determination of physically compromised and physically talented children were set at -1SD and +1SD, respectively. The results of all physical fitness tests showed that the share of physically compromised children exceeded ten percent for both genders. The largest number of boys and girls were physically compromised with regard to endurance and balance, respectively. On the other hand, boys proved to be most physically talented with regard to endurance, and girls with regard to explosive power. Gender differences were most obvious with regard to general endurance, as 21 per cent of the boys were physically compromised as opposed to 13 per cent of the girls. As for physical talent, we observed less gender-related differences. The results indicate increasing differences in physical fitness among children from northeastern Slovenia. The implementation of curricular and extracurricular sports activities should aim at reducing the number of physically compromised children. On the other hand, it would make sense to encourage physically talented children to get involved in organized forms of exercise.

  12. MHD Integrated Topping Cycle Project. Sixteenth quarterly technical progress report, May 1991--July 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    The Magnetohydrodynamics (MHD) Integrated Topping Cycle (ITC) Project represents the culmination of the proof-of-concept (POC) development stage in the US Department of Energy (DOE) program to advance MHD technology to early commercial development stage utility power applications. The project is a joint effort, combining the skills of three topping cycle component developers: TRW, Avco/TDS, and Westinghouse. TRW, the prime contractor and system integrator, is responsible for the 50 thermal megawatt (50 MW{sub t}) slagging coal combustion subsystem. Avco/TDS is responsible for the MHD channel subsystem (nozzle, channel, diffuser, and power conditioning circuits), and Westinghouse is responsible for the current consolidation subsystem. The ITC Project will advance the state-of-the-art in MHD power systems with the design, construction, and integrated testing of 50 MW{sub t} power train components which are prototypical of the equipment that will be used in an early commercial scale MHD utility retrofit. Long duration testing of the integrated power train at the Component Development and Integration Facility (CDIF) in Butte, Montana will be performed, so that by the early 1990`s, an engineering data base on the reliability, availability, maintainability and performance of the system will be available to allow scaleup of the prototypical designs to the next development level. This Sixteenth Quarterly Technical Progress Report covers the period May 1, 1991 to July 31, 1991.

  13. Review of the integrated thermal and nonthermal treatment system studies. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    This report contains a review and evaluation of three systems analysis studies performed by LITCO on integrated thermal treatment systems and integrated nonthermal treatment systems for the remediation of mixed low-level waste stored throughout the US Department of Energy weapons complex. The review was performed by an independent team of nine researchers from the Energy and Environmental Research Center, Science Applications International Corporation, the Waste Policy Institute, and Virginia Tech. The three studies reviewed were as follows: Integrated Thermal Treatment System Study, Phase 1 -- issued July 1994; Integrated Thermal Treatment System Study, Phase 2 -- issued February 1996; and Integrated Nonthermal Treatment System Study -- drafted March 1996. The purpose of this review was to (1) determine whether the assumptions of the studies were adequate to produce an unbiased review of both thermal and nonthermal systems, (2) to identify the critical areas of the studies that would benefit from further investigation, and (3) to develop a standard template that could be used in future studies to assure a sound application of systems engineering.

  14. Middle school integrated science, mathematics and technology curriculum. Final report, September 30, 1991--December 31, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Brecher, K.

    1994-03-01

    The Project ``Middle School Integrated Science, Mathematics and Technology Curriculum`` had two goals: (1) to survey the literature of energy education; and (2) to develop a theme for a possible integrated middle school energy based curriculum. We aimed to respond to the challenge of developing thematic integrated curricula as advocated by the NSTA, AAAS and other organizations analyzing the future of American science and mathematics education. The survey of middle school energy curriculum materials has been completed. A list of the resources surveyed are included in this report. Though many energy based curriculum materials have been produced, none of them appears to be broadly disseminated throughout the country. Some energy based curriculum materials are far less well developed than others. We found that an integrated set of modular materials concerning the energy based theme of light and optics does not now exist. If they were developed, they could be broadly disseminated throughout middle school courses in the physical and biological sciences, as well as in new integrated science courses proposed as part of the current science education reform movement. These types of modular materials could also provide a powerful means of student exploration of new technologies such as microcomputers.

  15. MHD Integrated Topping Cycle Project. Sixteenth quarterly technical progress report, May 1991--July 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    The Magnetohydrodynamics (MHD) Integrated Topping Cycle (ITC) Project represents the culmination of the proof-of-concept (POC) development stage in the US Department of Energy (DOE) program to advance MHD technology to early commercial development stage utility power applications. The project is a joint effort, combining the skills of three topping cycle component developers: TRW, Avco/TDS, and Westinghouse. TRW, the prime contractor and system integrator, is responsible for the 50 thermal megawatt (50 MW{sub t}) slagging coal combustion subsystem. Avco/TDS is responsible for the MHD channel subsystem (nozzle, channel, diffuser, and power conditioning circuits), and Westinghouse is responsible for the current consolidation subsystem. The ITC Project will advance the state-of-the-art in MHD power systems with the design, construction, and integrated testing of 50 MW{sub t} power train components which are prototypical of the equipment that will be used in an early commercial scale MHD utility retrofit. Long duration testing of the integrated power train at the Component Development and Integration Facility (CDIF) in Butte, Montana will be performed, so that by the early 1990`s, an engineering data base on the reliability, availability, maintainability and performance of the system will be available to allow scaleup of the prototypical designs to the next development level. This Sixteenth Quarterly Technical Progress Report covers the period May 1, 1991 to July 31, 1991.

  16. Idaho National Laboratory Integrated Safety Management System FY 2012 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Farren Hunt

    2012-12-01

    Idaho National Laboratory (INL) performed an Annual Effectiveness Review of the Integrated Safety Management System (ISMS), per 48 Code of Federal Regulations (CFR) 970.5223 1, “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and identified target areas for focused improvements and assessments for fiscal year (FY) 2013. Results of the FY 2012 annual effectiveness review demonstrated that the INL’s ISMS program was significantly strengthened. Actions implemented by the INL demonstrate that the overall Integrated Safety Management System is sound and ensures safe and successful performance of work while protecting workers, the public, and environment. This report also provides several opportunities for improvement that will help further strengthen the ISM Program and the pursuit of safety excellence. Demonstrated leadership and commitment, continued surveillance, and dedicated resources have been instrumental in maturing a sound ISMS program. Based upon interviews with personnel, reviews of assurance activities, and analysis of ISMS process implementation, this effectiveness review concludes that ISM is institutionalized and is “Effective”.

  17. Mixed waste focus area integrated technical baseline report. Phase I, Volume 2: Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-16

    This document (Volume 2) contains the Appendices A through J for the Mixed Waste Focus Area Integrated Technical Baseline Report Phase I for the Idaho National Engineering Laboratory. Included are: Waste Type Managers` Resumes, detailed information on wastewater, combustible organics, debris, unique waste, and inorganic homogeneous solids and soils, and waste data information. A detailed list of technology deficiencies and site needs identification is also provided.

  18. Audit of Systems of Electronic Money on the Basis of Integrated Bank Reporting

    Directory of Open Access Journals (Sweden)

    Melnychenko Oleksandr V.

    2013-12-01

    Full Text Available The article is devoted to audit and oversight of systems of electronic money on the basis of integrated reporting of banks as main participants of such systems. The author offers for the first time methods of composition of integrated bank reporting – participants of systems of electronic money by parts, on the basis of which the auditors can assess and form opinions on social responsibility of payment organisations, interests of the society, business and state in the process of the use of an individual payment means. The author analyses definitions of oversight (observation over payment systems and systems of electronic money. Moreover, it offers methods of carrying out an audit of systems of electronic money by data of integrated bank reporting, on the basis of which assessment of influence of the use of this form of money funds upon bank employees, society in general and upon ensuring observation of rules of the current legislation by participants of systems of electronic money is carried out.

  19. White matter fiber compromise contributes differentially to attention and emotion processing impairment in alcoholism, HIV-infection, and their comorbidity.

    Science.gov (United States)

    Schulte, T; Müller-Oehring, E M; Sullivan, E V; Pfefferbaum, A

    2012-10-01

    Alcoholism (ALC) and HIV-1 infection (HIV) each affects emotional and attentional processes and integrity of brain white matter fibers likely contributing to functional compromise. The highly prevalent ALC+HIV comorbidity may exacerbate compromise. We used diffusion tensor imaging (DTI) and an emotional Stroop Match-to-Sample task in 19 ALC, 16 HIV, 15 ALC+HIV, and 15 control participants to investigate whether disruption of fiber system integrity accounts for compromised attentional and emotional processing. The task required matching a cue color to that of an emotional word with faces appearing between the color cue and the Stroop word in half of the trials. Nonmatched cue-word color pairs assessed selective attention, and face-word pairs assessed emotion. Relative to controls, DTI-based fiber tracking revealed lower inferior longitudinal fasciculus (ilf) integrity in HIV and ALC+HIV and lower uncinate fasciculus (uf) integrity in all three patient groups. Controls exhibited Stroop effects to positive face-word emotion, and greater interference was related to greater callosal, cingulum and ilf integrity. By contrast, HIV showed greater interference from negative Stroop words during color-nonmatch trials, correlating with greater uf compromise. For face trials, ALC and ALC+HIV showed greater Stroop-word interference, correlating with lower cingulate and callosal integrity. Thus, in HIV, conflict resolution was diminished when challenging conditions usurped resources needed to manage interference from negative emotion and to disengage attention from wrongly cued colors (nonmatch). In ALC and ALC+HIV, poorer callosal integrity was related to enhanced emotional interference suggesting curtailed interhemispheric exchange needed between preferentially right-hemispheric emotion and left-hemispheric Stroop-word functions.

  20. Secretion of salivary statherin is compromised in uncontrolled diabetic patients

    Directory of Open Access Journals (Sweden)

    Masahiro Izumi

    2015-06-01

    Conclusions and general significance: The results show that synthesis and secretion of statherin is reduced in diabetics and this reduction is salivary gland specific. As compromised salivary statherin secretion leads to increased oral health risk, this study indicates that routine oral health assessment of these patients is warranted.

  1. Evil Searching: Compromise and Recompromise of Internet Hosts for Phishing

    Science.gov (United States)

    Moore, Tyler; Clayton, Richard

    Attackers compromise web servers in order to host fraudulent content, such as malware and phishing websites. While the techniques used to compromise websites are widely discussed and categorized, analysis of the methods used by attackers to identify targets has remained anecdotal. In this paper, we study the use of search engines to locate potentially vulnerable hosts. We present empirical evidence from the logs of websites used for phishing to demonstrate attackers’ widespread use of search terms which seek out susceptible web servers. We establish that at least 18% of website compromises are triggered by these searches. Many websites are repeatedly compromised whenever the root cause of the vulnerability is not addressed. We find that 19% of phishing websites are recompromised within six months, and the rate of recompromise is much higher if they have been identified through web search. By contrast, other public sources of information about phishing websites are not currently raising recompromise rates; we find that phishing websites placed onto a public blacklist are recompromised no more frequently than websites only known within closed communities.

  2. Codeswitching and Compromise Strategies: Implications for Lexical Structure.

    Science.gov (United States)

    Jake, Janice L.; Myers-Scotton, Carol

    1997-01-01

    Deals with two compromise strategies: (1) embedded language islands (EL Islands), and (2) "bare forms" in code switching (CS) within the projection of complementizer. These elements are discussed within the framework of the Matrix Language Frame Model. Shows how this model provides an explanatory account for the occurrence of both EL…

  3. 22 CFR 213.25 - Standards for compromise.

    Science.gov (United States)

    2010-04-01

    ... proceedings. In evaluating the acceptability of the offer, the CFO may consider, among other factors, the... applicable exemptions available to the debtor under State and Federal law in determining the Government's ability to enforce collection. (b) USAID may compromise a claim, or recommend acceptance of a...

  4. 41 CFR 105-70.046 - Compromise or settlement.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Compromise or settlement. 105-70.046 Section 105-70.046 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General...

  5. 14 CFR 1264.145 - Compromise or settlement.

    Science.gov (United States)

    2010-01-01

    ... of compromise or settlement at any time, including proposals for alternative dispute resolution. (b... pendency of any judicial review under § 1264.141 or during the pendency of any civil action to collect... or settle a case under this part during the pendency of any judicial review under 31 U.S.C. 3805...

  6. Tissue response: biomaterials, dental implants, and compromised osseous tissue.

    Science.gov (United States)

    Babu RS, Arvind; Ogle, Orrett

    2015-04-01

    Tissue response represents an important feature in biocompatibility in implant procedures. This review article highlights the fundamental characteristics of tissue response after the implant procedure. This article also highlights the tissue response in compromised osseous conditions. Understanding the histologic events after dental implants in normal and abnormal bone reinforces the concept of case selection in dental implants.

  7. Time-to-Compromise Model for Cyber Risk Reduction Estimation

    Energy Technology Data Exchange (ETDEWEB)

    Miles A. McQueen; Wayne F. Boyer; Mark A. Flynn; George A. Beitel

    2005-09-01

    We propose a new model for estimating the time to compromise a system component that is visible to an attacker. The model provides an estimate of the expected value of the time-to-compromise as a function of known and visible vulnerabilities, and attacker skill level. The time-to-compromise random process model is a composite of three subprocesses associated with attacker actions aimed at the exploitation of vulnerabilities. In a case study, the model was used to aid in a risk reduction estimate between a baseline Supervisory Control and Data Acquisition (SCADA) system and the baseline system enhanced through a specific set of control system security remedial actions. For our case study, the total number of system vulnerabilities was reduced by 86% but the dominant attack path was through a component where the number of vulnerabilities was reduced by only 42% and the time-to-compromise of that component was increased by only 13% to 30% depending on attacker skill level.

  8. Exposure to inflammatory cytokines IL-1β and TNFα induces compromise and death of astrocytes; implications for chronic neuroinflammation.

    Directory of Open Access Journals (Sweden)

    Christa van Kralingen

    Full Text Available BACKGROUND: Astrocytes have critical roles in the human CNS in health and disease. They provide trophic support to neurons and are innate-immune cells with keys roles during states-of-inflammation. In addition, they have integral functions associated with maintaining the integrity of the blood-brain barrier. METHODS: We have used cytometric bead arrays and xCELLigence technology to monitor the to monitor the inflammatory response profiles and astrocyte compromise in real-time under various inflammatory conditions. Responses were compared to a variety of inflammatory cytokines known to be released in the CNS during neuroinflammation. Astrocyte compromise measured by xCELLigence was confirmed using ATP measurements, cleaved caspase 3 expression, assessment of nuclear morphology and cell death. RESULTS: Inflammatory activation (IL-1β or TNFα of astrocytes results in the transient production of key inflammatory mediators including IL-6, cell surface adhesion molecules, and various leukocyte chemoattractants. Following this phase, the NT2-astrocytes progressively become compromised, which is indicated by a loss of adhesion, appearance of apoptotic nuclei and reduction in ATP levels, followed by DEATH. The earliest signs of astrocyte compromise were observed between 24-48 h post cytokine treatment. However, significant cell loss was not observed until at least 72 h, where there was also an increase in the expression of cleaved-caspase 3. By 96 hours approximately 50% of the astrocytes were dead, with many of the remaining showing signs of compromise too. Numerous other inflammatory factors were tested, however these effects were only observed with IL-1β or TNFα treatment. CONCLUSIONS: Here we reveal direct sensitivity to mediators of the inflammatory milieu. We highlight the power of xCELLigence technology for revealing the early progressive compromise of the astrocytes, which occurs 24-48 hours prior to substantive cell loss. Death induced by IL

  9. Loss of GSNOR1 Function Leads to Compromised Auxin Signaling and Polar Auxin Transport.

    Science.gov (United States)

    Shi, Ya-Fei; Wang, Da-Li; Wang, Chao; Culler, Angela Hendrickson; Kreiser, Molly A; Suresh, Jayanti; Cohen, Jerry D; Pan, Jianwei; Baker, Barbara; Liu, Jian-Zhong

    2015-09-01

    Cross talk between phytohormones, nitric oxide (NO), and auxin has been implicated in the control of plant growth and development. Two recent reports indicate that NO promoted auxin signaling but inhibited auxin transport probably through S-nitrosylation. However, genetic evidence for the effect of S-nitrosylation on auxin physiology has been lacking. In this study, we used a genetic approach to understand the broader role of S-nitrosylation in auxin physiology in Arabidopsis. We compared auxin signaling and transport in Col-0 and gsnor1-3, a loss-of-function GSNOR1 mutant defective in protein de-nitrosylation. Our results showed that auxin signaling was impaired in the gsnor1-3 mutant as revealed by significantly reduced DR5-GUS/DR5-GFP accumulation and compromised degradation of AXR3NT-GUS, a useful reporter in interrogating auxin-mediated degradation of Aux/IAA by auxin receptors. In addition, polar auxin transport was compromised in gsnor1-3, which was correlated with universally reduced levels of PIN or GFP-PIN proteins in the roots of the mutant in a manner independent of transcription and 26S proteasome degradation. Our results suggest that S-nitrosylation and GSNOR1-mediated de-nitrosylation contribute to auxin physiology, and impaired auxin signaling and compromised auxin transport are responsible for the auxin-related morphological phenotypes displayed by the gsnor1-3 mutant.

  10. Integrated environmental control and monitoring in the intelligent workplace. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This project involved the design and engineering of the control and monitoring of environmental quality - visual, thermal, air - in the Intelligent Workplace. The research objectives were to study the performance of the individual systems, to study the integration issues related to each system, to develop a control plan, and to implement and test the integrated systems in a real setting. In this project, a control strategy with related algorithms for distributed sensors, actuators, and controllers for negotiating central and individual control of HVAC, lighting, and enclosure was developed in order to maximize user comfort, and energy and environmental effectiveness. The goal of the control system design in the Intelligent Workplace is the integration of building systems for optimization of occupant satisfaction, organizational flexibility, energy efficiency and environmental effectiveness. The task of designing this control system involves not only the research, development and demonstration of state-of-the-art mechanical and electrical systems, but also their integration. The ABSIC research team developed functional requirements for the environmental systems considering the needs of both facility manager and the user. There are three levels of control for the environmental systems: scheduled control, sensor control, and user control. The challenges are to achieve the highest possible levels of energy effectiveness simultaneously with the highest levels of user satisfaction. The report describes the components of each system, their implementation in the Intelligent Workplace and related control and monitoring issues.

  11. Study of integration issues to realize OTEC market potential. Third quarterly report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-09-01

    The specific objective of this study is to examine the commercialization of OTEC technology in the electric utility industry in the Gulf region of the United States. To accomplish this, the project staff is identifying the major issues that will arise in the integration of OTEC units into the power delivery systems in the Gulf Region. Among these issues are problems that must be resolved and barriers to be overcome. These are being identified and alternative approaches to resolving or overcoming them will be explored. This will permit the recommendation of preferred approaches to integration and these approaches will be assembled into strategies for OTEC commercialization. To accomplish this it is essential that a set of reference conditions be available against which problems and barriers, and approaches to resolving them can be measured. To provide this framework a set of assumptions relative to the OTEC systems, their competition, and deployment schedules was presented in the first quarterly report. These assumptions have been reviewed and evaluated and in some cases, found questionable. Earlier, there were no assumptions included that described the economic conditions which would prevail from the pesent through the period in which OTEC units will be integrated into utility systems. An expanded set of assumptions is presented which we feel are more representative of conditions under which OTEC units will be integrated. The analysis of commercialization issues and licensing of OTEC plants are discussed.

  12. Quarterly Report 11 for the Period October 1978 - December 1978 and Proceedings of the 11th Project Integration Meeting

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-10-01

    This report describes progress made by the Low-Cost Solar Array Project during the period October through December 1978. It includes task reports on silicon material processing, large-area silicon sheet development, encapsulation mate3rials testing and development, Project engineering and operations, and manufacturing techniques, plus the steps taken to integrate these efforts. it also includes a report on and copies of viewgraphs presented at the Project Integration Meeting held December 13-14, 1978.

  13. Process integration and waste heat recovery in Lithuanian and Danish industry. Final report phase 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    The present document forms the Final Report for the first phase of the project `Process Integration and Waste Heat Recovery in Lithuanian and Danish Industry`. The project is carried out in the period 1995-1998 in a co-operation between the COWI offices in Lyngby and Vilnius, The Technical University of Denmark (Institute for Energetics), Kaunas University of Technology (CIPAI) and Vilnius Technical University, financed by The Danish Ministry of Energy`s EFP-95-programme, Lithuanian Energy Agency as well as the participants. The first phase of the project has comprised the establishment of the CIPAI centre (Centre for Industrial Process Analysis and Integration) at Kaunas University of Technology, training and knowledge transfer as well as elaboration of 6 industrial case-studies within the area of `Process Integration and waste Heat Recovery`. The second phase of the project has comprised R and D activities in this area in order to present general conclusions from the project as well as to present new and improved methods and tools for PI-analysis. The aim of the Final Report for the first phase of the project is to summarise project activities and the achieved results from case-studies and from the operation of the CIPAI-centre in general. (au)

  14. The role of Organizational Change in Green IS: Integrating Sustainability in Projects

    NARCIS (Netherlands)

    Silvius, Gilbert

    2012-01-01

    Sustainability is without doubt one of the most important challenges of our time. How can we develop prosperity, without compromising the life of future generations? Companies are integrating concepts of sustainability in their marketing, corporate communications, annual reports and in their actions

  15. Information and analytical support of integrated reporting: evaluation of the stakeholders’ influence on the change of the created value

    Directory of Open Access Journals (Sweden)

    Yu. V. Novozhilova

    2017-01-01

    Full Text Available Information and analytical support of integrated reporting needs constant improvement, depending on the growing needs of the stakeholders. The main objective of integrated reporting is to explain how the organization creates value over time. The stakeholders play a key role in the process of value creation. Firms accumulate stakeholders’ resources and transform them, thereby meeting the needs of the parties and achieving their own goals. Building relationships with their stakeholders, organization establishes impact leverage to create value. Thus, the created value depends on the successful interaction with stakeholders. Therefore, the article is devoted to problem of information and analytical support of integrated reporting to the evaluation of created value, which is influenced by the stakeholders. The article emphasizes that an integrated quantitative measurement of value change is a complex and unresolved currently task. Integrated evaluation - a systematic analytical study, in the course of which is given summarizing evaluation of the effectiveness company. Such assessment activity is important and has a multi-purpose orientation under market conditions. The annual reports of companies are practically no integrated indicators characterizing created value. The author believes that integrated reporting should become a platform for the realization of the possibility of an integrated assessment of the created value. The results of the study are the development the methods of computation the “integrated index overall impact by the stakeholders on the company’s created value” and its testing on the example of the annual reports of the organization, which discloses information on the level of international best practice. The methodology of the research bases on such methods as analysis, synthesis, abstraction, simulation, comprehensive approach to knowledge, logical methods of research. Private indicators for the computation the

  16. Digital Radiography and Computed Tomography Project -- Fully Integrated Linear Detector ArrayStatus Report

    Energy Technology Data Exchange (ETDEWEB)

    Tim Roney; Robert Seifert; Bob Pink; Mike Smith

    2011-09-01

    The field-portable Digital Radiography and Computed Tomography (DRCT) x-ray inspection systems developed for the Project Manager for NonStockpile Chemical Materiel (PMNSCM) over the past 13 years have used linear diode detector arrays from two manufacturers; Thomson and Thales. These two manufacturers no longer produce this type of detector. In the interest of insuring the long term viability of the portable DRCT single munitions inspection systems and to improve the imaging capabilities, this project has been investigating improved, commercially available detectors. During FY-10, detectors were evaluated and one in particular, manufactured by Detection Technologies (DT), Inc, was acquired for possible integration into the DRCT systems. The remainder of this report describes the work performed in FY-11 to complete evaluations and fully integrate the detector onto a representative DRCT platform.

  17. Buried waste integrated demonstration Fiscal Year 1993 close-out report

    Energy Technology Data Exchange (ETDEWEB)

    Owens, K.J.; Hyde, R.A.

    1994-04-01

    The Buried Waste Integrated Demonstration (BWID) supports the applied research, development, demonstration, and evaluation of a multitude of advanced technologies. These technologies are being integrated to form a comprehensive remediation system for the effective and efficient remediation of buried waste. These efforts are identified and coordinated in support of the U.S. Department of Energy Environmental Restoration and Waste Management needs and objectives. BWID works with universities and private industry to develop these technologies, which are being transferred to the private sector for use nationally and internationally. A public participation policy has been established to provide stakeholders with timely and accurate information and meaningful opportunities for involvement in the technology development and demonstration process. To accomplish this mission of identifying technological solutions for remediation deficiencies, the Office of Technology Development initiated BWID at the Idaho National Engineering Laboratory. This report summarizes the activities of the BWID program during FY-93.

  18. MHD Integrated Topping Cycle Project. Seventeenth quarterly technical progress report, August 1, 1991--October 31, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-07-01

    This seventeenth quarterly technical progress report of the MHD Integrated Topping Cycle Project presents the accomplishments during the period August 1, 1991 to October 31, 1991. Manufacturing of the prototypical combustor pressure shell has been completed including leak, proof, and assembly fit checking. Manufacturing of forty-five cooling panels was also completed including leak, proof, and flow testing. All precombustor internal components (combustion can baffle and swirl box) were received and checked, and integration of the components was initiated. A decision was made regarding the primary and backup designs for the 1A4 channel. The assembly of the channel related prototypical hardware continued. The cathode wall electrical wiring is now complete. The mechanical design of the diffuser has been completed.

  19. Historical-critical Re-integration of the SED's Annual Reports into ECOS

    Science.gov (United States)

    Grolimund, Remo; Fäh, Donat

    2014-05-01

    With the establishment of the Swiss Earthquake Commission (SEC) as early as 1878, Switzerland has one of the oldest traditions of continual macroseismic data collection. Due to the use of a single intensity scale (Rossi-Forel) in a period spanning from the early 1880s into the 1960s this dataset might be considered as one of the most temporally extended stock of rather homogeneous macroseismic data. The work of the SEC and the Swiss Seismological Service (SED), established in 1914 as its successor organization, is relatively well documented in a series of annual reports (1879-1963; 1972-1974) which was assumed to have been adequately integrated in the original parametric catalogue version that had been compiled for the first Swiss Seismic Hazard map in the mid-1970s. For pragmatic reasons this earlier period of systematic scientific earthquake observation in Switzerland has thus not been addressed in-depth in the first phases of the historical-critical revision of the Earthquake Catalogue of Switzerland (ECOS-02; ECOS-09) and the reassessment process has mainly been limited to the complete revision of the damaging earthquakes with an assumed epicentral intensity of more than V (EMS-98). In the reassessment of events with a maximum intensity of less than VI (EMS) for the period 1878-1900 we have, however, realized that the wealth of macroseismic data gathered in the annuals is only incompletely integrated in ECOS. Moreover, from a methodological perspective, a significant part of the parametric information from the catalogue version compiled in the 1970s is questionable as the process of their determination is neither documented nor reproducible and thus lacking intersubjective traceability as a key criterion for qualitative research. Empirically, a considerable part of the catalogue data proved to be inconsistent with the critical examination of the information documented in the annual reports for example with regard to the appraisal of certainties. The comparison

  20. Methodology for design of adaptive interfaces for diagnostic workstations with integrated images and reports

    Science.gov (United States)

    Harreld, Michael R.; Valentino, Daniel J.; Liu, Brent J.; El-Saden, Suzie; Duckwiler, Gary R.

    1998-06-01

    Diagnostic workstations have generally lacked acceptance due to awkward interfaces, poor usability and lack of clinical data integration. We developed a new methodology for the design and implementation of diagnostic workstations and applied the methodology in diagnostic neuroradiology. The methodology facilitated the objective design and evaluation of optimal diagnostic features, including the integration of images and reports, and the implementation of intelligent and adaptive graphical user interfaces. As a test of this new methodology, we developed and evaluated a neuroradiological diagnostic workstation. The general goals of diagnostic neuroradiologists were modeled and directly used in the design of the UCLA Digital ViewBox, an object-oriented toolkit for medical imaging workstations. For case-specific goals, an object-oriented protocol toolkit was developed for rapid development and integration of new protocols, modes, and tools. Each protocol defines a way to arrange and process data in order to accomplish diagnostic goals that are specific to anatomy (e.g., a spine protocol), or to a suspected pathology (e.g., a tumor protocol). Each protocol was divided into modes that represent diagnostic reading tasks. Each mode was further broken down into functions supporting that task. Via a data mediator engine, the workstation communicated with clinical data repositories, including the UCLA HIS, Clinical RIS/PACS and individual DICOM compatible scanners. The data mediator served to transparently integrate, retrieve, and cache image and report data. Task-oriented Reading protocols automatically present the appropriate diagnostic information and diagnostic tools to the radiologist. We describe a protocol toolkit that enables the rapid design and implementation of customized reading protocols. We also present an intelligent layer that enables the automatic presentation of the appropriate information. This new methodology for diagnostic workstation design led to an

  1. Immediate Esthetic Rehabilitation of Periodontally Compromised Anterior Tooth Using Natural Tooth as Pontic

    Directory of Open Access Journals (Sweden)

    K. Pavan Kumar

    2016-01-01

    Full Text Available For patients who require removal of anterior teeth and their replacement various treatment modalities are available. With advancement in technology and availability of glass/polyethylene fibres, use of natural tooth as pontic with fibre reinforced composite restorations offers the promising results. The present case report describes management of periodontally compromised mandibular anterior tooth using natural tooth pontic with fibre reinforcement. A 1-year follow-up showed that the bridge was intact with good esthetics and no problem was reported.

  2. Data And Informatics Working Group On Virtual Data Integration Workshop Report

    Energy Technology Data Exchange (ETDEWEB)

    Williams, D. N. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Palanisamy, G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dam, K. K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-13

    This report is the outcome of a workshop that was commissioned by the Department of Energy’s Climate and Environmental Sciences Division (CESD) to examine current and future data infrastructure requirements that would be foundational to achieving CESD’s scientific mission goals. Over the past several years, data volumes in CESD disciplines have risen sharply to unprecedented levels (tens of petabytes). So too has the complexity and diversity of the research data (simulation, observation, and reanalysis) needing to be captured, stored, verified, analyzed, and integrated. With the trends of increased data volume (in the hundreds of petabytes), more complex analysis processes, and growing crossdisciplinary collaborations, it is timely to investigate whether the CESD community has the right computational and data support to realize the full scientific potential from its data collections. In recognition of the challenges, a partnership is forming across CESD and with national and international agencies to investigate the viability of creating an integrated, collaborative data infrastructure: a virtual laboratory. The overarching goal of this report is to identify the community’s key data technology requirements and high-priority development needs for sustaining and growing their scientific discovery potential. The report also aims to map these requirements to existing solutions and to identify gaps in current services, tools, and infrastructure that will need to be addressed in the short, medium, and long term so as not to impede scientific progress

  3. Securing Single Points of Compromise (SPoC)

    Energy Technology Data Exchange (ETDEWEB)

    Belangia, David Warren [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-06-25

    Securing the Single Points of Compromise that provide central services to the institution’s environment is paramount to success when trying to protect the business. (Fisk, 2014) Time Based Security mandates protection (erecting and ensuring effective controls) that last longer than the time to detect and react to a compromise. When enterprise protections fail, providing additional layered controls for these central services provides more time to detect and react. While guidance is readily available for securing the individual critical asset, protecting these assets as a group is not often discussed. Using best business practices to protect these resources as individual assets while leveraging holistic defenses for the group increases the opportunity to maximize protection time, allowing detection and reaction time for the SPoCs that is commensurate with the inherent risk of these centralized services.

  4. Roles of Melatonin in Fetal Programming in Compromised Pregnancies

    Directory of Open Access Journals (Sweden)

    Yu-Chieh Chen

    2013-03-01

    Full Text Available Compromised pregnancies such as those associated with gestational diabetes mellitus, intrauterine growth retardation, preeclampsia, maternal undernutrition, and maternal stress may negatively affect fetal development. Such pregnancies may induce oxidative stress to the fetus and alter fetal development through the epigenetic process that may affect development at a later stage. Melatonin is an oxidant scavenger that reverses oxidative stress during the prenatal period. Moreover, the role of melatonin in epigenetic modifications in the field of developmental programming has been studied extensively. Here, we describe the physiological function of melatonin in pregnancy and discuss the roles of melatonin in fetal programming in compromised pregnancies, focusing on its involvement in redox and epigenetic mechanisms.

  5. Creating clones, kids & chimera: liberal democratic compromise at the crossroads.

    Science.gov (United States)

    Adams, Nathan A

    2004-01-01

    The objective of this article is to find middle ground between the supporters and opponents of biotechnology by perpetuating the existing legal compromise pertaining to the complete range of health and welfare doctrines relevant to the biotechnological industry. The author aspires neither to add to nor detract from this liberal democratic consensus, but to preserve its constitutive balance between positivism and natural law and over-regulation and under-regulation in the hopes of stabilizing new political fault lines developing around the few biotechnological innovations already grabbing headlines. The most feasible solution is to extend the existing liberal democratic compromise with respect to equal protection, reproductive rights, the First Amendment, human subject experimentation, patent law, and parental rights. This includes banning or monopolizing certain biotechnologies and extending substantive special respect to the ex vivo living human embryo. Biotechnology must not be left to regulate itself.

  6. Air-Source Integrated Heat Pump for Near-Zero Energy Houses: Technology Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, Richard W [ORNL; Rice, C Keith [ORNL; Baxter, Van D [ORNL; Craddick, William G [ORNL

    2007-07-01

    This report documents the development of an air-source integrated heat pump (AS-IHP) through the third quarter of FY2007. It describes the design, analyses and testing of the AS-IHP, and provides performance specifications for a field test prototype and proposed control strategy. The results obtained so far continue to support the AS-IHP being a promising candidate to meet the energy service needs for DOE's development of a Zero Energy Home (ZEH) by the year 2020.

  7. AFTI/SITAN (Advanced Fighter Technology Integration/Sandia Inertial Terrain-Aided Navigation) final report

    Energy Technology Data Exchange (ETDEWEB)

    Fellerhoff, J.R.

    1988-11-01

    Sandia Inertial Terrain-Aided Navigation (SITAN) provides continuous position fixes to an inertial navigation system (INS) by real-time comparison of radar altimeter ground clearance measurements with stored digital terrain elevation data (DTED). This is accomplished by using an extended Kalman filter algorithm to estimate the errors in the reference trajectory provided by an INS. In this report, Sandia National Laboratories documents the results of a reimbursable effort funded by the Air Force Wright Aeronautical Laboratories (AFWAL) Avionics Laboratory to flight test SITAN as implemented onboard the Advanced Fighter Technology Integration (AFTI)F-16. 5 refs., 101 figs., 1 tab.

  8. Striking a Balance between Program Requirements and GT Principles: Writing a compromised GT proposal

    Directory of Open Access Journals (Sweden)

    Sherry L. Xie, Ph.D. Candidate

    2009-06-01

    Full Text Available Glaser’s term “compromised GT proposal” (2001, p.114 refers to the type of Grounded Theory (GT proposal that is written in order to conform to the requirements of a standardized qualitative research proposal. A GT proposal needs only to supply information on the area of interest, the data source and a statement of method to the effect that the researcher begin to collect, code and analyse the data and let the theory emerge. Thus, the proposal may only occupy “a page or two” (Glaser, 2001, p. 111. Whilst being consistent with the methodology, a GT proposal sometimes has to give way to the format specified by a PhD program or committee even though the format was not defined for a GT proposal and in some areas, conflicts with GT principles; for example, the format may require a literature review. This short paper reports on my experience of writing a compromised GT proposal as a first-time GT researcher. It describes how both Glaser’s advice on writing compromised GT research proposals and the characteristics of the substantive area of the proposed research were used to satisfy program requirements while still maintaining GT fundamentals.

  9. Addressing diversity in schools through dialogue and compromise

    DEFF Research Database (Denmark)

    Olsen, Tore Vincents

    2018-01-01

    This article evaluates a decentralized Danish model for dealing with cultural and religious diversity at individual schools. This evaluation is based upon normative theories of toleration, recognition and domination and examines whether the model implies compromise with the (liberal) educational...... values stipulated in the national legislation. The model, reconstructed from government publications, is based on reaching accommodation through dialogue between school staff and parents/students, with the pragmatic aim of facilitating the participation of students in everyday school activities...

  10. Sophia's Compromises and Fielding's Creation of a Patriarchal World

    Institute of Scientific and Technical Information of China (English)

    宋芳

    2007-01-01

    Traditionally, critics maintain that Henry Fielding has created an ideal heroine, Sophia, in his novel The History of Tom Jones.This paper argues that Sophia is not a very successful woman character since she fails to be an autonomous individual and has to make compromises with the patriarchal world created by Fielding.Relating to this, Fielding's male Chauvinism embodied in this novel will also be explored by analyzing other women characters.

  11. Compromised Agency: The Case of BabyLegs

    Directory of Open Access Journals (Sweden)

    Max Liboiron

    2017-09-01

    Full Text Available The concept of agency is ubiquitous in STS, particularly regarding cases of alternative ways of knowing and doing science such as civic, citizen, and feminist sciences, among others. Yet the focus on agency often glosses over the constraints placed on agents, particularly within asymmetrical power relations. This article follows the case of BabyLegs, a do-it-yourself monitoring tool for marine microplastic pollution, and the attempt to keep the technology open source within an intellectual property (IP system set up to privatize it. The tactics used to design BabyLegs as a feminine, silly, doll-tool to discredit the device in the eyes of an IP system that valued traditional gender roles lead to the eventual success of keeping the device open source. Yet, those same tactics also reinforced and reproduced the structures of power and essentialism they were designed to resist. I characterize this technological ambivalence as compromise, and argue that all agency exercised within asymmetrical power relations is compromised. This is not to say resistance is futile, but that agency is never pure, and this recognition lets us be more intentional in how we might compromise as practitioners of diverse scientific knowledges.

  12. Integrated data base report--1996: US spent nuclear fuel and radioactive waste inventories, projections, and characteristics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    The Integrated Data Base Program has compiled historic data on inventories and characteristics of both commercial and U.S. Department of Energy (DOE) spent nuclear fuel (SNF) and commercial and U.S. government-owned radioactive wastes. Inventories of most of these materials are reported as of the end of fiscal year (FY) 1996, which is September 30, 1996. Commercial SNF and commercial uranium mill tailings inventories are reported on an end-of-calendar year (CY) basis. All SNF and radioactive waste data reported are based on the most reliable information available from government sources, the open literature, technical reports, and direct contacts. The information forecasted is consistent with the latest DOE/Energy Information Administration (EIA) projections of U.S. commercial nuclear power growth and the expected DOE-related and private industrial and institutional activities. The radioactive materials considered, on a chapter-by-chapter basis, are SNF, high-level waste, transuranic waste, low-level waste, uranium mill tailings, DOE Environmental Restoration Program contaminated environmental media, naturally occurring and accelerator-produced radioactive material, and mixed (hazardous and radioactive) low-level waste. For most of these categories, current and projected inventories are given through FY 2030, and the radioactivity and thermal power are calculated based on reported or estimated isotopic compositions.

  13. The Role Of Grenelle II In Corporate Social Responsibility Integrated Reporting

    Directory of Open Access Journals (Sweden)

    Radoslaw Wolniak

    2013-12-01

    Full Text Available There is in the paper, the analysis of the Grenelle II act from Corporate Social Responsibility reporting point of view. France has long been an important global champion of corporate sustainability reporting. While this trend has advanced the integration of CSR into business practices, the increasing number of regulations has also made it more complicated and costly for international companies to create reports that fulfill the differing requirements of each foreign law. The Grenelle 2 law adopted in July 2010, implements the Grenelle 1 goals. It sets specific objectives, strategic, incentives and regulations. This Act aims at forcing companies to progress in reporting their environmental and social information: there is no sanction (such as fines, requirements are on a “comply or explain” basis and the implementation is progressive. The main advantage of such an Grenelle II Act is a beginning and will have to be rewritten and improved, taking into account the international movement – is to shift minds regarding CSR. CSR and extra-financial information has nothing to do with communication anymore: it is clearly a strategic and management process, facilitated by the reporting process.

  14. Integrated data base report - 1994: US spent nuclear fuel and radioactive waste inventories, projections, and characteristics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    The Integrated Data Base Program has compiled historic data on inventories and characteristics of both commercial and U.S. Department of Energy (DOE) spent nuclear fuel and commercial and U.S. government-owned radioactive wastes. Except for transuranic wastes, inventories of these materials are reported as of December 31, 1994. Transuranic waste inventories are reported as of December 31, 1993. All spent nuclear fuel and radioactive waste data reported are based on the most reliable information available from government sources, the open literature, technical reports, and direct contacts. The information forecasted is consistent with the latest DOE/Energy Information Administration (EIA) projections of U.S. commercial nuclear power growth and the expected DOE-related and private industrial and institutional activities. The radioactive materials considered, on a chapter-by-chapter basis, are spent nuclear fuel, high-level waste, transuranic waste, low-level waste, commercial uranium mill tailings, DOE Environmental Restoration Program contaminated environmental media, commercial reactor and fuel-cycle facility decommissioning wastes, and mixed (hazardous and radioactive) low-level waste. For most of these categories, current and projected inventories are given through the calendar-year 2030, and the radioactivity and thermal power are calculated based on reported or estimated isotopic compositions.

  15. SRC burn test in 700-hp oil-designed boiler. Volume 1. Integrated report. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    1983-09-01

    This burn test program was conducted during the period of August 1982 to February 1983 to demonstrate that Solvent Refined Coal (SRC) products can displace petroleum as a boiler fuel in oil- and gas-designed boilers. The test program was performed at the U.S. Department of Energy's Pittsburgh Energy Technology Center (PETC). Three forms of SRC (pulverized SRC, a solution of SRC dissolved in process-derived distillates, and a slurry of SRC and water) and No. 6 Fuel Oil were evaluated in the 700-hp (30 x 10/sup 6/ Btu/hour) watertube, oil-designed boiler facility at PETC. The test program was managed by the International Coal Refining Company (ICRC) and sponsored by the Department of Energy. Other organizations were involved as necessary to provide the expertise required to execute the test program. This final report represents an integrated overview of the test program conducted at PETC. More detailed information with preliminary data can be obtained from separate reports prepared by PETC, Southern Research Institute, Wheelabrator-Frye, Babcock and Wilcox, and Combustion Engineering. These are presented as Annex Volumes A-F. 25 references, 41 figures, 15 tables.

  16. 'Integration'

    DEFF Research Database (Denmark)

    Olwig, Karen Fog

    2011-01-01

    After a long history dominated by out-migration, Denmark, Norway and Sweden have, in the past 50 years, become immigration societies. This article compares how these Scandinavian welfare societies have sought to incorporate immigrants and refugees into their national communities. It suggests that......, while the countries have adopted disparate policies and ideologies, differences in the actual treatment and attitudes towards immigrants and refugees in everyday life are less clear, due to parallel integration programmes based on strong similarities in the welfare systems and in cultural notions...... of equality in the three societies. Finally, it shows that family relations play a central role in immigrants’ and refugees’ establishment of a new life in the receiving societies, even though the welfare society takes on many of the social and economic functions of the family....

  17. Integrated approach towards the application of horizontal wells to improve waterflooding performance. 1995 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Kelkar, M.; Liner, C.; Kerr, D.

    1996-06-01

    This annual report describes the progress during the third year of the project on Integrated Approach Towards the Application of Horizontal Wells to Improve Waterflooding Performance. This project is funded under the Department of Energy`s Class I program which is targeted towards improving the reservoir performance of mature oil fields located in fluvially dominated deltaic geological environments. The project involves using an integrated approach to characterize the reservoir followed by proposing an appropriate reservoir management strategy to improve the field performance. In the first stage of the project, the type of data we integrated include cross borehole seismic surveys, geological interpretation based on the logs and the cores, and the engineering information. In contrast, during the second stage of the project, we intend to use only conventional data to construct the reservoir description. This report covers the results of the implementation from the first stage of the project. It also discusses the work accomplished so far for the second stage of the project. The preliminary results look promising from the field implementation. The production from the Self Unit (location of Stage I) has increased by 35 bbls/day with additional increase anticipated with further implementation. Based on our understanding of the first stage, we hope to examine a greater area of the Glenn Pool field for additional increase in production. We have collected available core and log data and have finished the initial geological description. Although not a direct part of this project, we also have initiated a 3-D seismic survey of the area which should help us in improving the reservoir description.

  18. Technical Report on Preliminary Methodology for Enhancing Risk Monitors with Integrated Equipment Condition Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Ramuhalli, Pradeep; Coles, Garill A.; Coble, Jamie B.; Hirt, Evelyn H.

    2013-09-17

    Small modular reactors (SMRs) generally include reactors with electric output of ~350 MWe or less (this cutoff varies somewhat but is substantially less than full-size plant output of 700 MWe or more). Advanced SMRs (AdvSMRs) refer to a specific class of SMRs and are based on modularization of advanced reactor concepts. AdvSMRs may provide a longer-term alternative to traditional light-water reactors (LWRs) and SMRs based on integral pressurized water reactor concepts currently being considered. Enhancing affordability of AdvSMRs will be critical to ensuring wider deployment. AdvSMRs suffer from loss of economies of scale inherent in small reactors when compared to large (~greater than 600 MWe output) reactors. Some of this loss can be recovered through reduced capital costs through smaller size, fewer components, modular fabrication processes, and the opportunity for modular construction. However, the controllable day-to-day costs of AdvSMRs will be dominated by operation and maintenance (O&M) costs. Technologies that help characterize real-time risk are important for controlling O&M costs. Risk monitors are used in current nuclear power plants to provide a point-in-time estimate of the system risk given the current plant configuration (e.g., equipment availability, operational regime, and environmental conditions). However, current risk monitors are unable to support the capability requirements listed above as they do not take into account plant-specific normal, abnormal, and deteriorating states of active components and systems. This report documents technology developments that are a step towards enhancing risk monitors that, if integrated with supervisory plant control systems, can provide the capability requirements listed and meet the goals of controlling O&M costs. The report describes research results from an initial methodology for enhanced risk monitors by integrating real-time information about equipment condition and POF into risk monitors.

  19. Implementation and Validation of PACS Integrated Peer Review for Discrepancy Recording of Radiology Reporting.

    Science.gov (United States)

    Olthof, A W; van Ooijen, P M A

    2016-09-01

    The purpose of this work is to demonstrate the possibility of implementation of a PACS-integrated peer review system based on RADPEER™ classification providing a step-wise implementation plan utilizing features already present in the standard PACS implementation and without the requirement of additional software development. Furthermore, we show the usage and effects of the system during the first 30 months of usage. To allow fast and easy implementation into the daily workflow the key-word feature of the PACS was used. This feature allows to add a key-word to an imaging examination for easy searching in the PACS database (e.g. by entering keywords for different kinds of pathology). For peer review we implemented a keyword structure including a code for each of the existing RADPEER™ scoring language terms and a keyword with the phrase "second reading" followed by the name of the individual radiologist. The use of the short-keys to enter the codes in relation to the peer review was a simple to use solution. During the study 599 reports were peer reviewed. The active participation in this study of the radiologists varies and ranges from 3 to 327 reviews per radiologist. The number of peer review is highest in CT and CR. There are no significant technical obstacles to implement a PACS-integrated RADPEER™ -system based on key-words allowing easy integration of peer review into the daily routine without the requirement of additional software. Peer review implemented in a non-random setting based on relevant priors could already help in increasing the quality of radiological reporting and serve as continuing education among peers. Decisiveness, tact and trust are needed to promote use of the system and collaborative discussion of the results by radiologist.

  20. Progress Report 16 for the period April-September 1980, and the proceedings of the 16th Project Integration Meeting

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, R.R.

    1980-01-01

    Progress made by the Low-Cost Solar Array Project during the period April to September 1980, is reported in detail. Progress on project analysis and integration; technology development in silicon material, large-area silicon sheet and encapsulation; production process and equipment development; engineering, and operations is described. A report on, and copies of visual presentations made at, the Project Integration Meeting held September 24 and 25, 1980 are included.

  1. Idaho National Laboratory Integrated Safety Management System FY 2016 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, Farren J. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-12-01

    Idaho National Laboratory’s (INL’s) Integrated Safety Management System (ISMS) effectiveness review of fiscal year (FY) 2016 shows that INL has integrated management programs and safety elements throughout the oversight and operational activities performed at INL. The significant maturity of Contractor Assurance System (CAS) processes, as demonstrated across INL’s management systems and periodic reporting through the Management Review Meeting process, over the past two years has provided INL with current real-time understanding and knowledge pertaining to the health of the institution. INL’s sustained excellence of the Integrated Safety and effective implementation of the Worker Safety and Health Program is also evidenced by other external validations and key indicators. In particular, external validations include VPP, ISO 14001, DOELAP accreditation, and key Laboratory level indicators such as ORPS (number, event frequency and severity); injury/illness indicators such as Days Away, Restricted and Transfer (DART) case rate, back & shoulder metric and open reporting indicators, demonstrate a continuous positive trend and therefore improved operational performance over the last few years. These indicators are also reflective of the Laboratory’s overall organizational and safety culture improvement. Notably, there has also been a step change in ESH&Q Leadership actions that have been recognized both locally and complex-wide. Notwithstanding, Laboratory management continues to monitor and take action on lower level negative trends in numerous areas including: Conduct of Operations, Work Control, Work Site Analysis, Risk Assessment, LO/TO, Fire Protection, and Life Safety Systems, to mention a few. While the number of severe injury cases has decreased, as evidenced by the reduction in the DART case rate, the two hand injuries and the fire truck/ambulance accident were of particular concern. Aggressive actions continue in order to understand the causes and

  2. Management of periodontally compromised patient by orthodontic treatment: Does it help esthetically and biologically?

    Directory of Open Access Journals (Sweden)

    Subhash C Rao

    2012-01-01

    Full Text Available Adults are always keen to know whether they can still opt for orthodontic treatment and they often ask the same question to the orthodontist and the orthodontist replies, it primarily depends on the health of the bone supporting the teeth. Yes, it is the bone health which is of prime importance to undergo orthodontic treatment. Here is a case report of a patient who underwent orthodontic treatment because of lower midline spacing and protrusion of the upper anteriors. The bone health of the upper and lower anteriors was compromised. At the end of the treatment, there was marked improvement in the bone level and the profile of the patient.

  3. Capitalizing on Context: Curriculum Integration in Career and Technical Education. A Joint Report of the NRCCTE Curriculum Integration Workgroup

    Science.gov (United States)

    Pearson, Donna; Sawyer, Jennifer; Park, Travis; Santamaria, Laura; van der Mandele, Elizabeth; Keene, Barrett; Taylor, Marissa

    2010-01-01

    The National Research Center for Career and Technical Education (NRCCTE) has undertaken three scientifically based research studies in an effort to determine whether the integration of career and technical education (CTE) courses with academic content can increase student achievement. These include the Math-in-CTE study, completed in 2005 (also…

  4. Periodontics: 8. Periodontal problems associated with compromised anterior teeth.

    Science.gov (United States)

    Byrne, Patrick J; Irwin, Chris; Mullally, Brian; Allen, Edith; Ziada, Hassan

    2008-01-01

    Periodontal disease can significantly impact on the appearance of the anterior teeth. Prior to any definitive treatment, stabilization of the periodontal condition is a requirement. Treatment options can range from the placement of simple restorations, through orthodontic realignment, to the extraction and replacement of hopeless teeth. Each treatment plan must be individually tailored to the patient and level of periodontal disease, and must include provision for maintenance periodontal therapy. Periodontal diseases may compromise the prognosis of anterior teeth. Management is challenging and clinicians should take into consideration the short and long-term survival in treatment planning.

  5. The Swiss approach to finding compromises in nuclear waste governance

    Energy Technology Data Exchange (ETDEWEB)

    Kuppler, Sophie; Grunwald, Armin [Karlsruhe Institute of Technology (Germany). Inst. for Technology Assessment and Systems Analysis

    2015-07-01

    In Switzerland, a new site selection procedure is being implemented since 2008. This procedure, which is laid down in a 'sectoral plan', shows strong elements of public participation and transparency and can be considered a step away from the classical 'decide-announce-defend' approach in decision-making. This procedure tends towards a more governance-oriented approach based on ideas of 'civility' of decision-making. Despite this renewal, the Swiss case clearly shows that any kind of selection process has to be considered as a 'working compromise', which needs to be adapted when new challenges emerge.

  6. Study of the impacts of regulations affecting the acceptance of integrated community energy systems. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Feurer, Duane A.; Weaver, Clifford L.; Rielley, Kevin J.; Gallagher, Kevin C.; Harmon, Susan B.; Hejna, David T.; Kitch, Edmund W.

    1981-01-01

    A detailed description is presented of the laws and programs of the State of North Carolina governing the regulation of public energy utilities, the siting of energy generating and transmission facilities, the municipal franchising of public energy utilities, and the prescription of rates to be charged by utilities including attendant problems of cost allocations, rate base and operating expense determinations, and rate of return allowances. These laws and programs are analyzed to identify impediments which they may present to the implementation of Integrated Community Energy Systems (ICES). This report is one of fifty-one separate volumes which describe such regulatory programs at the Federal level and in each state as background to the report entitled Community Energy Systems and the Law of Public Utilities - Volume One: An Overview. This report also contains a summary of a strategy described in Volume One - An Overview for overcoming these impediments by working within the existing regulatory framework and by making changes in the regulatory programs to enhance the likelihood of ICES implementation.

  7. Integrated Yoga and Naturopathy module in management of Metabolic Syndrome: A case report

    Directory of Open Access Journals (Sweden)

    Swathi Gowda

    2017-01-01

    Full Text Available A 50-year-old male participant with sedentary lifestyle, diagnosed with Metabolic Syndrome (MetS [obesity, Type-2 diabetes mellitus, hypertension] and hypothyroidism since 2013, was administered integrated Yoga and Naturopathy (IYN for 6 weeks as a tailor made individualized protocol at the residential integrative medical facility in Bangalore between October and November 2015. The results showed reduction in weight (97.9 kg to 74.6 kg, Body Mass Index (BMI (35.1 kg/m2 to 27.86 kg/m2, total cholesterol (192 mg% to 145 mg%, triglycerides (153 mg% to 90 mg%, Low Density Lipoprotein (LDL (124 mg% to 81 mg%, High Density Lipoprotein (HDL (40 mg% to 46 mg%, fasting blood glucose (110 mg/dl to 75 mg/dl, postprandial glucose (267 mg/dl to 100 mg/dl, glycated hemoglobin (HbA1c (7.8%–7.1%, Thyroid Stimulating Hormone (TSH (6.90 μIU/ml to 3.052 μIU/ml. Following the intervention, the anti-hypertensive, oral hypoglycemic, thyroid raising and analgesic medicines were not required to be continued. His knee pain minimized on discharge as observed on a Visual Analog Scale. He had an improved feeling of wellness and overall functional health. All his parameters were within normal range at the 12-weeks follow-up, as he had incorporated the lifestyle program into his daily routine. This case report suggests that lifestyle change by integration of specific non-drug Yoga and Naturopathic intervention is useful in the management of MetS.

  8. High accuracy integrated global positioning system/inertial navigation system LDRD: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Owen, T.E.; Meindl, M.A.; Fellerhoff, J.R.

    1997-03-01

    This report contains the results of a Sandia National Laboratories Directed Research and Development (LDRD) program to investigate the integration of Global Positioning System (GPS) and inertial navigation system (INS) technologies toward the goal of optimizing the navigational accuracy of the combined GPSANS system. The approach undertaken is to integrate the data from an INS, which has long term drifts, but excellent short term accuracy, with GPS carrier phase signal information, which is accurate to the sub-centimeter level, but requires continuous tracking of the GPS signals. The goal is to maintain a sub-meter accurate navigation solution while the vehicle is in motion by using the GPS measurements to estimate the INS navigation errors and then using the refined INS data to aid the GPS carrier phase cycle slip detection and correction and bridge dropouts in the GPS data. The work was expanded to look at GPS-based attitude determination, using multiple GPS receivers and antennas on a single platform, as a possible navigation aid. Efforts included not only the development of data processing algorithms and software, but also the collection and analysis of GPS and INS flight data aboard a Twin Otter aircraft. Finally, the application of improved navigation system accuracy to synthetic aperture radar (SAR) target location is examined.

  9. Hearing impairment and audiovisual speech integration ability: a case study report.

    Science.gov (United States)

    Altieri, Nicholas; Hudock, Daniel

    2014-01-01

    Research in audiovisual speech perception has demonstrated that sensory factors such as auditory and visual acuity are associated with a listener's ability to extract and combine auditory and visual speech cues. This case study report examined audiovisual integration using a newly developed measure of capacity in a sample of hearing-impaired listeners. Capacity assessments are unique because they examine the contribution of reaction-time (RT) as well as accuracy to determine the extent to which a listener efficiently combines auditory and visual speech cues relative to independent race model predictions. Multisensory speech integration ability was examined in two experiments: an open-set sentence recognition and a closed set speeded-word recognition study that measured capacity. Most germane to our approach, capacity illustrated speed-accuracy tradeoffs that may be predicted by audiometric configuration. Results revealed that some listeners benefit from increased accuracy, but fail to benefit in terms of speed on audiovisual relative to unisensory trials. Conversely, other listeners may not benefit in the accuracy domain but instead show an audiovisual processing time benefit.

  10. Integrated analysis of particle interactions at hadron colliders Report of research activities in 2010-2015

    Energy Technology Data Exchange (ETDEWEB)

    Nadolsky, Pavel M. [Southern Methodist Univ., Dallas, TX (United States)

    2015-08-31

    The report summarizes research activities of the project ”Integrated analysis of particle interactions” at Southern Methodist University, funded by 2010 DOE Early Career Research Award DE-SC0003870. The goal of the project is to provide state-of-the-art predictions in quantum chromodynamics in order to achieve objectives of the LHC program for studies of electroweak symmetry breaking and new physics searches. We published 19 journal papers focusing on in-depth studies of proton structure and integration of advanced calculations from different areas of particle phenomenology: multi-loop calculations, accurate long-distance hadronic functions, and precise numerical programs. Methods for factorization of QCD cross sections were advanced in order to develop new generations of CTEQ parton distribution functions (PDFs), CT10 and CT14. These distributions provide the core theoretical input for multi-loop perturbative calculations by LHC experimental collaborations. A novel ”PDF meta-analysis” technique was invented to streamline applications of PDFs in numerous LHC simulations and to combine PDFs from various groups using multivariate stochastic sampling of PDF parameters. The meta-analysis will help to bring the LHC perturbative calculations to the new level of accuracy, while reducing computational efforts. The work on parton distributions was complemented by development of advanced perturbative techniques to predict observables dependent on several momentum scales, including production of massive quarks and transverse momentum resummation at the next-to-next-to-leading order in QCD.

  11. Integrated MHD bottoming cycle: Second quarterly report, November 1, 1987--January 31, 1988

    Energy Technology Data Exchange (ETDEWEB)

    None

    1988-03-01

    The Integrated MHD Bottoming Cycle project, progress for September and October relates to Task 1--Modification of the Existing Coal Pulverizer and Dryer System, and Task 2--Design, Fabrication, and Installation of an Automated Spent Seed/Ash Handling System. Drafts of the Preliminary Design Review packages for the Modification of the Existing Pulverizer and Dryer System and the Automated Spent Seed/Ash Handling System were submitted to DOE/PETC for review. B and W reviewed the system criteria for drying Montana Rosebud coal to 3% moisture. B and W concluded that the system suggested in the RFP would not achieve the required drying. B and W recommended that a pre-dryer be used in combination with drying in the pulverizer. B and W is proceeding to define the performance requirements and costs of a system using a pre-dryer. This report contains a project and task descriptions.

  12. Integrated MHD Bottoming Cycle: First quarterly report, September 11--October 31, 1987

    Energy Technology Data Exchange (ETDEWEB)

    None

    1987-12-01

    The Integrated MHD Bottoming Cycle project progress for September and October relates to Task 1--Modification of the Existing Coal Pulverizer and Dryer System, and Task 2--Design, Fabrication, and Installation of an Automated Spent Seed/Ash Handling System. The project team was assembled and committed to the project. Team members attended a kickoff meeting at the Pittsburgh Energy Technology Center. The design approaches for the pulverizer modifications, the spent seed/ash handling system, and the air heater replacement for the existing vitiation heater were presented. Planning was initiated to distribute the authorized funding among the tasks. Work was started on the Management Plan, including the Work Plan, Milestone Schedule Plan, and Cost. This report covers task description and project status for the first two months of the project.

  13. WP 2 Report: Integrated Status Quo and Trends Assessment in Wuxi. Overview of WP 2 Results

    Energy Technology Data Exchange (ETDEWEB)

    Dienst, Carmen; Hoeller, Samuel; Saurat, Mathieu; Schneider, Clemens; Xia-Bauer, Chun (Wuppertal Institute (Germany)); Oberheitmann, Andreas (China Environmental Research (China)); Fischer, Tom; Gemmer, Marco; Jiang Tong (China Meteorological Administration, National Climate Centre (China)); Wang Can; Wang Haoping (Tsinghua University, Research Centre for International Environmental Policy (China)); Ren Hongyan; Sui Xinying (Wuxi Low Carbon Development Research Centre (China))

    2013-04-01

    The overall project will scientifically explore the Low Carbon Future City (LCFC) concept in two case studies: the German region of Dusseldorf and the Chinese city of Wuxi, Jiangsu Province. The Wuppertal Institute together with a consortium of Chinese scientific institutes is developing integrated low carbon city strategies for the two pilot regions. The project is funded by the German Stiftung Mercator. Provided in this report, as part of the scientific analysis of the Chinese pilot region, is a comprehensive status quo and trends assessment of greenhouse gas emissions, climate change and resource use in Wuxi. It includes a GHG inventory, a business-as-usual scenario for GHG emissions, scenarios for future climate change and its impacts as well as an analysis of future resource use in the energy and buildings sector of Wuxi. Based on this assessment, the authors have selected key sectors for which low carbon scenarios as well as policy strategies will be finalised.

  14. The first stage of BFS integrated system for nuclear materials control and accounting. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    The BFS computerized accounting system is a network-based one. It runs in a client/server mode. The equipment used in the system includes a computer network consisting of: One server computer system, including peripheral hardware and three client computer systems. The server is located near the control room of the BFS-2 facility outside of the `stone sack` to ensure access during operation of the critical assemblies. Two of the client computer systems are located near the assembly tables of the BFS-1 and BFS-2 facilities while the third one being the Fissile Material Storage. This final report details the following topics: Computerized nuclear material accounting methods; The portal monitoring system; Test and evaluation of item control technology; Test and evaluation of radiation based nuclear material measurement equipment; and The integrated demonstration of nuclear material control and accounting methods.

  15. Final report for the Integrated and Robust Security Infrastructure (IRSI) laboratory directed research and development project

    Energy Technology Data Exchange (ETDEWEB)

    Hutchinson, R.L.; Hamilton, V.A.; Istrail, G.G.; Espinoza, J.; Murphy, M.D.

    1997-11-01

    This report describes the results of a Sandia-funded laboratory-directed research and development project titled {open_quotes}Integrated and Robust Security Infrastructure{close_quotes} (IRSI). IRSI was to provide a broad range of commercial-grade security services to any software application. IRSI has two primary goals: application transparency and manageable public key infrastructure. IRSI must provide its security services to any application without the need to modify the application to invoke the security services. Public key mechanisms are well suited for a network with many end users and systems. There are many issues that make it difficult to deploy and manage a public key infrastructure. IRSI addressed some of these issues to create a more manageable public key infrastructure.

  16. Placental Abruption With Delayed Fetal Compromise in Maternal Acetaminophen Toxicity.

    Science.gov (United States)

    Taney, Juliana; Anastasio, Hannah; Paternostro, Amanda; Berghella, Vincenzo; Roman, Amanda

    2017-07-01

    After maternal acetaminophen overdose, fetal fulminant liver failure, stillbirth, neonatal death, or preterm delivery may occur. A 27-year-old woman, gravida 2 para 1, presented at 28 weeks of gestation after unintentional acetaminophen overdose. Four days after ingestion, her laboratory values worsened, including serum aspartate aminotransferase of 5,460 units/L, alanine aminotransferase of 4,936 units/L, and international normalized ratio of 2.9. On day 6 after ingestion, fetal monitoring showed minimal variability with repetitive variable and late decelerations, which prompted cesarean delivery when a hematoma was noted on the maternal placental surface, consistent with placental abruption. The neonate showed no evidence of hepatic dysfunction. Review of the literature suggests that maternal acetaminophen overdose in the second and third trimester is associated with a 5% incidence of fetal compromise (mostly the result of nonreassuring fetal status leading to delivery or stillbirth) occurring within 6 days of ingestion. Maternal acetaminophen overdose can be associated with delayed fetal compromise, suggesting the importance of continued fetal surveillance several days after ingestion.

  17. Diffusion-reaction compromise the polymorphs of precipitated calcium carbonate

    Institute of Scientific and Technical Information of China (English)

    Han Wang; Wenlai Huang; Yongsheng Han

    2013-01-01

    Diffusion is seldom considered by chemists and materialists in the preparation of materials while it plays an important role in the field of chemical engineering.If we look at crystallization at the atomic level,crystal growth in a solution starts from the diffusion of ions to the growing surface followed by the incorporation of ions into its lattice.Diffusion can be a rate determining step for the growth of crystals.In this paper,we take the crystallization of calcium carbonate as an example to illustrate the microscopic processes of diffusion and reaction and their compromising influence on the morphology of the crystals produced.The diffusion effect is studied in a specially designed three-cell reactor.Experiments show that a decrease of diffusion leads to retardation of supersaturation and the formation of a continuous concentration gradient in the reaction cell,thus promoting the formation of cubic calcite particles.The reaction rate is regulated by temperature.Increase of reaction rate favors the formation of needle-like aragonite particles.When diffusion and reaction play joint roles in the reaction system,their compromise dominates the formation of products,leading to a mixture of cubic and needle-like particles with a controllable ratio.Since diffusion and reaction are universal factors in the preparation of materials,the finding of this paper could be helpful in the controlled synthesis of other materials.

  18. Integrated Energy System with Beneficial Carbon Dioxide (CO2) Use - Final Scientific/Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Xiaolei; Rink, Nancy T

    2011-04-29

    This report presents an integrated energy system that combines the production of substitute natural gas through coal hydrogasification with an algae process for beneficial carbon dioxide (CO2) use and biofuel production (funded under Department of Energy (DOE) contract DE-FE0001099). The project planned to develop, test, operate and evaluate a 2 ton-per-day coal hydrogasification plant and 25-acre algae farm at the Arizona Public Service (APS) 1000 Megawatt (MW) Cholla coal-fired power plant in Joseph City, Arizona. Conceptual design of the integrated system was undertaken with APS partners Air Liquide (AL) and Parsons. The process engineering was separated into five major areas: flue gas preparation and CO2 delivery, algae farming, water management, hydrogasification, and biofuel production. The process flow diagrams, energy and material balances, and preliminary major equipment needs for each major area were prepared to reflect integrated process considerations and site infrastructure design basis. The total project also included research and development on a bench-scale hydrogasifier, one-dimensional (1-D) kinetic-model simulation, extensive algae stressing, oil extraction, lipid analysis and a half-acre algae farm demonstration at APS?s Redhawk testing facility. During the project, a two-acre algae testing facility with a half-acre algae cultivation area was built at the APS Redhawk 1000 MW natural gas combined cycle power plant located 55 miles west of Phoenix. The test site integrated flue gas delivery, CO2 capture and distribution, algae cultivation, algae nursery, algae harvesting, dewatering and onsite storage as well as water treatment. The site environmental, engineering, and biological parameters for the cultivators were monitored remotely. Direct biodiesel production from biomass through an acid-catalyzed transesterification reaction and a supercritical methanol transesterification reaction were evaluated. The highest oil-to-biodiesel conversion of 79

  19. Bariatric surgery results: reporting clinical characteristics and adverse outcomes from an integrated healthcare delivery system.

    Science.gov (United States)

    Li, Robert A; Fisher, David P; Dutta, Sanjoy; O'Brien, Rebecca M; Ackerson, Lynn M; Sorel, Michael E; Sidney, Stephen

    2015-01-01

    Limited data have been reported on bariatric surgery within a large, high-volume regional multicenter integrated healthcare delivery system. Review clinical characteristics and short- and intermediate-term outcomes and adverse events from a bariatric surgery program within an integrated healthcare delivery system. Single high-volume, multicenter regional integrated healthcare delivery system. Adult patients who underwent primary bariatric surgery during 2010-2011 were reviewed. Clinical characteristics, outcomes, and weight loss results were extracted from the electronic medical record. A total of 2399 patients were identified within the study period. The 30-day rates of clinical outcomes for Roux-en-Y gastric bypass (RYGB; n = 1313) and sleeve gastrectomy (SG; n = 1018) were 2.9% for readmission, 3.0% for major complications, .8% for reoperation, and 0% for mortality. One-year and 2-year weight loss results were as follows: percent weight loss (%WL) was 31.4 (±SD 8.5) and 34.2±12.0% for SG and 34.1±9.3 and 39.1±11.9 for RYGB; percent excess weight loss (%EBWL) was 64.2±18.0 and 69.8±23.7 for SG and 68.0±19.3 and 77.8±23.7 for RYGB; percent excess body mass index loss (%EBMIL) was 72.9±21.0 and 77.7±22.4 for SG and 76.6±22.1% and 85.6±21.6 for RYGB. Follow-up for each procedure at 1 year was 76% for SG (n = 778) and 80% for RYGB (n = 1052) and at 2 years was 65% for SG (n = 659) and 67% for RYGB (n = 875). A large regional high-volume multicenter bariatric program within an integrated healthcare delivery system can produce excellent short-term results with low rates of short- and intermediate-term adverse outcomes. Copyright © 2015 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  20. Integrating Sustainable Development and Climate Change in the IPCC Fourth Assessment Report

    Energy Technology Data Exchange (ETDEWEB)

    Munasinghe, M.; Canziani, O.; Davidson, O.; Metz, B.; Parry, M.; Harrison, M. [Munasinghe Institute for Development MIND, Colombo (Sri Lanka)

    2003-07-01

    The Third Assessment Report of the IPCC did take into account the nexus between climate change and sustainable development and attempted to assess the linkages between these two. However, much more remains to be done in providing a comprehensive assessment of this nexus, and how it is likely to affect human civilization in the decades ahead. It is for this reason that the issue of sustainable development is going to be incorporated as a major cross cutting theme in the Fourth Assessment Report of the IPCC. The Expert Meeting held in Colombo on Climate Change and Sustainable Development was the first of two expert meetings approved by the IPCC Plenary in Paris, in February 2003 (see Annex A for details). Sustainable development had been identified as a Cross Cutting Theme (CCT) for the Third Assessment Report (TAR), but was not developed fully therein. The Colombo Expert Meeting was held early, to enable the outcomes to inform the two IPCC Scoping Meetings (scheduled for May and September 2003), and to eventually provide guidance to the Lead Authors. At the IPCC Plenary XX, Paris, February 2003, seven Cross Cutting Themes (CCTs) were approved as forming a fundamental aspect of the structure of the forthcoming Fourth Assessment Report (AR4). These themes are: Risk and Uncertainty; Regional Integration; Water; Key Vulnerabilities including Article 2 issues; Adaptation and Mitigation; Sustainable Development; Technology. Introductory presentations were made by invited speakers, covering many of the key aspects of sustainable development, including linkages both from and to climate change. Summaries of these presentations are provided in this section, while original PowerPoint versions of the presentations are included in Part B of the volume.

  1. Instrumentation Needs for Integral Primary System Reactors (IPSRs) - Task 1 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Gary D. Storrick; Bojan Petrovic; Luca Oriani; Lawrence E. Conway; Diego Conti

    2005-09-30

    This report presents the results of the Westinghouse work performed under Task 1 of this Financial Assistance Award and satisfies a Level 2 Milestone for the project. While most of the signals required for control of IPSRs are typical of other PWRs, the integral configuration poses some new challenges in the design or deployment of the sensors/instrumentation and, in some cases, requires completely new approaches. In response to this consideration, the overall objective of Task 1 was to establish the instrumentation needs for integral reactors, provide a review of the existing solutions where available, and, identify research and development needs to be addressed to enable successful deployment of IPSRs. The starting point for this study was to review and synthesize general characteristics of integral reactors, and then to focus on a specific design. Due to the maturity of its design and availability of design information to Westinghouse, IRIS (International Reactor Innovative and Secure) was selected for this purpose. The report is organized as follows. Section 1 is an overview. Section 2 provides background information on several representative IPSRs, including IRIS. A review of the IRIS safety features and its protection and control systems is used as a mechanism to ensure that all critical safety-related instrumentation needs are addressed in this study. Additionally, IRIS systems are compared against those of current advanced PWRs. The scope of this study is then limited to those systems where differences exist, since, otherwise, the current technology already provides an acceptable solution. Section 3 provides a detailed discussion on instrumentation needs for the representative IPSR (IRIS) with detailed qualitative and quantitative requirements summarized in the exhaustive table included as Appendix A. Section 3 also provides an evaluation of the current technology and the instrumentation used for measurement of required parameters in current PWRs. Section 4

  2. U.S. Department of Energy Integrated Manufacturing & Processing Predoctoral Fellowships. 2000-2001 Annual Progress Report. Reporting period - July 1, 2000 - June 30, 2001

    Energy Technology Data Exchange (ETDEWEB)

    Willis, J.

    2001-08-28

    Administration and management of predoctoral fellowship program for the reporting period. The objective of the program was threefold: to create a pool of PhD's trained in the integrated approach to manufacturing and processing, to promote academic interest in the field, and to attract talented professionals to this challenging area of engineering. It was anticipated that the program would result in the creation of new manufacturing methods that would contribute to improved energy efficiency, to better utilization of scarce resources, and to less degradation of the environment. Emphasis in the competition was on integrated systems of manufacturing and the integration of product design with manufacturing processes.

  3. OTEC platform configuration and integration. Volume II. Technical concept. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-07-07

    The configuration, integration, and evaluation studies performed in the first phase of this contract resulted in a ranking of the most feasible platform candidates for commercial OTEC applications. On the basis of the results obtained from three individual contractors performing the same study, the Department of Energy made selections of two platform hulls for each contractor for conceptual designs. For Phase-II studies, M. Rosenblatt and Son, Inc. (MR and S) project team was given the SPAR and SPHERE platforms to perform not only conceptual designs for, but also cost and time schedules and sensitivity analyses. This is the second volume of a three-volume MR and S report, and it presents the results of conceptual designs for the two platforms, the facilities and equipment required for construction, deployment, and operation of these platforms, and cost estimates and time schedules. All conceptual design work is performed for the baseline site on West Coast of Florida. The cost differentials and other considerations involved with deploying the platforms in the New Orleans and Puerto Rico sites are also presented. As an end product of the complete study, the costs for the SPAR and the SPHERE platforms are reported both in terms of acquisition costs in 1978 dollars and life cycle costs in dollars per kilowatt.

  4. Integration of AMS and ERDS Measurement Data into NARAC Dispersion Models FY05 Technology Integration Project Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Foster, K; Arnold, E; Bonner, D; Eme, B; Fischer, K; Gash, J; Nasstrom, J; Walker, H; Guber, A; Logan, C; Wasiolek, P; Fulton, J

    2005-09-20

    Staff from Lawrence Livermore National Laboratory (LLNL), Bechtel Nevada Remote Sensing Laboratory (RSL), and Sandia National Laboratory (SNL) completed the proposed work for the Technology Integration Project titled Integration of AMS and ERDS Measurement Data into NARAC Dispersion Models. The objectives of this project were to develop software to convert Aerial Measurement Survey (AMS) and Emergency Response Data System (ERDS) field measurement data into a standard electronic format for transmission to the National Atmospheric Release Advisory Center (NARAC), and to streamline aspects of the NARAC operational atmospheric dispersion modeling system to quickly process these data for use in generating consequence calculations based on refined, field measurement-based estimates of the source strength. Although NARAC continues to develop and maintain a state-of-the-art atmospheric dispersion modeling system, model predictions are constrained by the availability of information to properly characterize the source term. During an actual atmospheric release, very little may be known initially about the source material properties, amount, or release time and location. Downwind measurements often provide the best information about the scope and nature of the release. The timely integration of field measurement data with model calculations is an obvious approach toward improving the model consequence predictions. By optimizing these predictions a more accurate representation of the consequences may be provided to (a) predict contamination levels which may be below the detectable limit of sensors, but which may still pose a significant hazard, (b) determine contamination is areas where measurements have not yet been made, and (c) prioritize the locations of future measurement surveys. By automating and streamlining much of the related field measurement data processing, these optimized predictions may be provided within a significantly reduced period, and with a reduction in

  5. The role of integrated indicators in exhibiting business contribution to sustainable development: a survey of sustainability reporting initiatives

    Directory of Open Access Journals (Sweden)

    Fernando Azcárate

    2011-08-01

    Full Text Available This paper aims to analyse the role of integrated indicators included in sustainability reporting initiatives in exhibiting business contribution to Sustainable Development. Content analysis of five core initiatives has been carried out to identify strong or weak sustainability arguments within the whole set of indicators. According to the findings, the analyzed initiatives raise a collection of integrated indicators that suggest managerial capture of the concept of Sustainable Development.

  6. MHD Technology Transfer, Integration and Review Committee. Fifth semi-annual status report, April 1990--September 1990

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    This fifth semi-annual status report of the MHD Technology Transfer, Integration, and Review Committee (TTIRC) summarizes activities of the TTIRC during the period April 1990 through September 1990. It includes summaries and minutes of committee meetings, progress summaries of ongoing Proof-of-Concept (POC) contracts, discussions pertaining to technical integration issues in the POC program, and planned activities for the next six months.

  7. It's Not What You Have, But How You Use It: Compromises in Mobile Device Use

    CERN Document Server

    Tungare, Manas

    2008-01-01

    As users begin to use many more devices for personal information management (PIM) than just the traditional desktop computer, it is essential for HCI researchers to understand how these devices are being used in the wild and their roles in users' information environments. We conducted a study of 220 knowledge workers about their devices, the activities they performed on each, and the groups of devices used together. Our findings indicate that several devices are often used in groups; integrated multi-function portable devices have begun to replace single-function devices for communication (e.g. email and IM). Users use certain features opportunistically because they happen to be carrying a multi-function device with them. The use of multiple devices and multi-function devices is fraught with compromises as users must choose and make trade-offs among various factors.

  8. MHD Technology Transfer, Integration and Review Committee. Seventh semi-annual status report, April 1991--September 1991

    Energy Technology Data Exchange (ETDEWEB)

    1993-02-01

    This seventh semi-annual status report of the MHD Technology Transfer, Integration and Review Committee (TTIRC) summarizes activities of the TTIRC during the period April 1991 through September 1991. It includes a summary and minutes of the General Committee meeting, progress summaries of ongoing POC contracts, discussions pertaining to technical integration issues in the POC program, and planned activities for the next six months. The meeting included test plan with Western coal, seed regeneration economics, power management for the integrated topping cycle and status of the Clean Coal Technology Proposal activities. Appendices cover CDIF operations HRSR development, CFFF operations etc.

  9. MHD Technology Transfer, Integration and Review Committee. Seventh semi-annual status report, April 1991--September 1991

    Energy Technology Data Exchange (ETDEWEB)

    1993-02-01

    This seventh semi-annual status report of the MHD Technology Transfer, Integration and Review Committee (TTIRC) summarizes activities of the TTIRC during the period April 1991 through September 1991. It includes a summary and minutes of the General Committee meeting, progress summaries of ongoing POC contracts, discussions pertaining to technical integration issues in the POC program, and planned activities for the next six months. The meeting included test plan with Western coal, seed regeneration economics, power management for the integrated topping cycle and status of the Clean Coal Technology Proposal activities. Appendices cover CDIF operations HRSR development, CFFF operations etc.

  10. Report of study group 4.3 ''pipeline integrity management and safety''

    Energy Technology Data Exchange (ETDEWEB)

    Clavel, P.

    2000-07-01

    This report highlights the Pipeline integrity Management methods being implemented by gas companies. These aim at maintaining the current high safety level, prevent major hazards, ensure the integrity of the pipeline and protect people and environment in the vicinity of the pipeline in the most cost effective way. It should be noticed that Pipeline Integrity Management aspects, technical and organisational, are included in the more general framework of the Safety Management System. Currently, more and more gas companies implement such a system on the basis of standards like ISO 9000 and so on. In this way, the report shows how practices of Pipeline Integrity Management are continually developing in order to adapt to their environment, and to improve performance. Past experience and imminent developments show that Pipeline Integrity Management is a flexible and efficient approach to improve safety in the long term. Consequently, Pipeline Integrity Management Systems are, under the control of authorities, the best alternative to additional safety regulations. Within the context of deregulation of the European markets and globalization Pipeline Integrity Management appears to be a tool to promote the gas industry in the eyes of the authorities, the market regulators and the customers (industrialists,...). (author)

  11. Solar energy grid integration systems : final report of the Florida Solar Energy Center Team.

    Energy Technology Data Exchange (ETDEWEB)

    Ropp, Michael (Northern Plains Power Technologies, Brookings, SD); Gonzalez, Sigifredo; Schaffer, Alan (Lakeland Electric Utilities, Lakeland, FL); Katz, Stanley (Satcon Technology Corporation, Boston, MA); Perkinson, Jim (Satcon Technology Corporation, Boston, MA); Bower, Ward Isaac; Prestero, Mark (Satcon Technology Corporation, Boston, MA); Casey, Leo (Satcon Technology Corporation, Boston, MA); Moaveni, Houtan (Florida Solar Energy Center of the University of Central Florida, Cocoa, FL); Click, David (Florida Solar Energy Center of the University of Central Florida, Cocoa, FL); Davis, Kristopher (Florida Solar Energy Center of the University of Central Florida, Cocoa, FL); Reedy, Robert (Florida Solar Energy Center of the University of Central Florida, Cocoa, FL); Kuszmaul, Scott S.; Sena-Henderson, Lisa; David, Carolyn; Akhil, Abbas Ali

    2012-03-01

    Initiated in 2008, the Solar Energy Grid Integration Systems (SEGIS) program is a partnership involving the U.S. DOE, Sandia National Laboratories, private sector companies, electric utilities, and universities. Projects supported under the program have focused on the complete-system development of solar technologies, with the dual goal of expanding utility-scale penetration and addressing new challenges of connecting large-scale solar installations in higher penetrations to the electric grid. The Florida Solar Energy Center (FSEC), its partners, and Sandia National Laboratories have successfully collaborated to complete the work under the third and final stage of the SEGIS initiative. The SEGIS program was a three-year, three-stage project that include conceptual design and market analysis in Stage 1, prototype development and testing in Stage 2, and moving toward commercialization in Stage 3. Under this program, the FSEC SEGIS team developed a comprehensive vision that has guided technology development that sets one methodology for merging photovoltaic (PV) and smart-grid technologies. The FSEC team's objective in the SEGIS project is to remove barriers to large-scale general integration of PV and to enhance the value proposition of photovoltaic energy by enabling PV to act as much as possible as if it were at the very least equivalent to a conventional utility power plant. It was immediately apparent that the advanced power electronics of these advanced inverters will go far beyond conventional power plants, making high penetrations of PV not just acceptable, but desirable. This report summarizes a three-year effort to develop, validate and commercialize Grid-Smart Inverters for wider photovoltaic utilization, particularly in the utility sector.

  12. [Amputation or reconstruction of a circulatory compromised severely injured extremity?].

    Science.gov (United States)

    Høiness, P; Røise, O

    1999-11-20

    18 patients treated with primary or secondary amputations after severe lower limb open fractures were studied. All limbs had clinical signs of a compromised circulation at the primary evaluation. The various injuries are described and discussed with respect to the general guidelines for primary amputation. The Mangled Extremity Severity Score (MESS) and Nerve, Ischemia, Soft tissues, Skeletal, Shock, Age (NISSSA) scores were calculated. In view of the described injuries, primary amputation was indicated in ten patients according to the general recommendations, 11 patients according to NISSSA and 15 patients according to MESS. Delayed amputation leads t a significantly (p = 0.005) higher number of operative procedures than early amputation (9.2 vs. 2.9 treatments). The decision of whether to amputate or not should be based on sound clinical judgement, but injury scores such as MESS and NISSSA may be helpful.

  13. Protecting Privacy of Shared Epidemiologic Data without Compromising Analysis Potential

    Directory of Open Access Journals (Sweden)

    John Cologne

    2012-01-01

    Full Text Available Objective. Ensuring privacy of research subjects when epidemiologic data are shared with outside collaborators involves masking (modifying the data, but overmasking can compromise utility (analysis potential. Methods of statistical disclosure control for protecting privacy may be impractical for individual researchers involved in small-scale collaborations. Methods. We investigated a simple approach based on measures of disclosure risk and analytical utility that are straightforward for epidemiologic researchers to derive. The method is illustrated using data from the Japanese Atomic-bomb Survivor population. Results. Masking by modest rounding did not adequately enhance security but rounding to remove several digits of relative accuracy effectively reduced the risk of identification without substantially reducing utility. Grouping or adding random noise led to noticeable bias. Conclusions. When sharing epidemiologic data, it is recommended that masking be performed using rounding. Specific treatment should be determined separately in individual situations after consideration of the disclosure risks and analysis needs.

  14. Food irradiation: Special solutions for the immuno-compromised

    Science.gov (United States)

    Mohácsi-Farkas, Csilla

    2016-12-01

    Safety of food is particularly important for immuno-compromised patients, because these people are vulnerable to all sorts of infectious complications and foodborne pathogens as well, and even organisms normally considered non-pathogenic may cause problems. According to the guidelines published by the FDA, immunocompromised patients have to avoid high-risk foods, and advised to consume only pasteurized juice, milk or cheese, and well-cooked eggs, poultry, meat and fish. In the frame of an IAEA CRP the objective was to develop, in collaborations with the healthcare community, the use of irradiation to increase the variety, availability and acceptability of foods for immunocompromised, for example irradiated fresh produce (fruits, vegetables, salads) and ready-to-eat meals. Further aim was to widen the acceptance of irradiated foods by the healthcare and regulatory communities.

  15. Glutathione synthesis is compromised in erythrocytes from individuals with HIV.

    Science.gov (United States)

    Morris, Devin; Ly, Judy; Chi, Po-Ting; Daliva, John; Nguyen, Truongson; Soofer, Charleen; Chen, Yung C; Lagman, Minette; Venketaraman, Vishwanath

    2014-01-01

    We demonstrated that the levels of enzymes responsible for the synthesis of glutathione (GSH) such as glutathione synthase (GSS), glutamate-cysteine ligase-catalytic subunit (GCLC), and glutathione reductase (GSR) were significantly reduced in the red blood cells (RBCs) isolated from individuals with human immunodeficiency virus (HIV) infection and this reduction correlated with decreased levels of intracellular GSH. GSH content in RBCs can be used as a marker for increased overall oxidative stress and immune dysfunctions caused by HIV infection. Our data supports our hypothesis that compromised levels of GSH in HIV infected individuals' is due to decreased levels of GSH-synthetic enzymes. The role of GSH in combating oxidative stress and improving the functions of immune cells in HIV patients' indicates the benefit of an antioxidant supplement which can reduce the cellular damage and promote the functions of immune cells.

  16. Compromising Tor Anonymity Exploiting P2P Information Leakage

    CERN Document Server

    Manils, Pere; Blond, Stevens Le; Kaafar, Mohamed Ali; Castelluccia, Claude; Legout, Arnaud; Dabbous, Walid

    2010-01-01

    Privacy of users in P2P networks goes far beyond their current usage and is a fundamental requirement to the adoption of P2P protocols for legal usage. In a climate of cold war between these users and anti-piracy groups, more and more users are moving to anonymizing networks in an attempt to hide their identity. However, when not designed to protect users information, a P2P protocol would leak information that may compromise the identity of its users. In this paper, we first present three attacks targeting BitTorrent users on top of Tor that reveal their real IP addresses. In a second step, we analyze the Tor usage by BitTorrent users and compare it to its usage outside of Tor. Finally, we depict the risks induced by this de-anonymization and show that users' privacy violation goes beyond BitTorrent traffic and contaminates other protocols such as HTTP.

  17. Enhanced susceptibility to predation in corals of compromised condition

    Directory of Open Access Journals (Sweden)

    Allan J. Bright

    2015-09-01

    Full Text Available The marine gastropod, Coralliophila abbreviata, is an obligate corallivore that causes substantial mortality in Caribbean Acropora spp. Considering the imperiled status of Acropora cervicornis and A. palmata, a better understanding of ecological interactions resulting in tissue loss may enable more effective conservation strategies. We examined differences in susceptibility of A. cervicornis to C. abbreviata predation based on coral tissue condition. Coral tissue condition was a strong determinant of snail prey choice, with snails preferring A. cervicornis fragments that were diseased or mechanically damaged over healthy fragments. In addition, snails always chose fragments undergoing active predation by another snail, while showing no preference for a non-feeding snail when compared with an undisturbed prey fragment. These results indicate that the condition of A. cervicornis prey influenced foraging behavior of C. abbreviata, creating a potential feedback that may exacerbate damage from predation in coral populations compromised by other types of disturbance.

  18. Enhanced susceptibility to predation in corals of compromised condition.

    Science.gov (United States)

    Bright, Allan J; Cameron, Caitlin M; Miller, Margaret W

    2015-01-01

    The marine gastropod, Coralliophila abbreviata, is an obligate corallivore that causes substantial mortality in Caribbean Acropora spp. Considering the imperiled status of Acropora cervicornis and A. palmata, a better understanding of ecological interactions resulting in tissue loss may enable more effective conservation strategies. We examined differences in susceptibility of A. cervicornis to C. abbreviata predation based on coral tissue condition. Coral tissue condition was a strong determinant of snail prey choice, with snails preferring A. cervicornis fragments that were diseased or mechanically damaged over healthy fragments. In addition, snails always chose fragments undergoing active predation by another snail, while showing no preference for a non-feeding snail when compared with an undisturbed prey fragment. These results indicate that the condition of A. cervicornis prey influenced foraging behavior of C. abbreviata, creating a potential feedback that may exacerbate damage from predation in coral populations compromised by other types of disturbance.

  19. Glutathione synthesis is compromised in erythrocytes from individuals with HIV

    Directory of Open Access Journals (Sweden)

    Vishwanath eVenketaraman

    2014-04-01

    Full Text Available We demonstrated that the levels of enzymes responsible for the synthesis of glutathione (GSH such as glutathione synthase (GSS, glutamate-cysteine ligase-catalytic subunit (GCLC and glutathione reductase (GSR were significantly reduced in the red blood cells (RBCs isolated from individuals with human immunodeficiency virus (HIV infection and this reduction correlated with decreased levels of intracellular GSH. GSH content in RBCs can be used as a marker for increased overall oxidative stress and immune dysfunctions caused by HIV infection. Our data supports our hypothesis that compromised levels of GSH in HIV infected individuals’ is due to decreased levels of GSH-synthetic enzymes. The role of GSH in combating oxidative stress and improving the functions of immune cells in HIV patients’ indicates the benefit of an antioxidant supplement which can reduce the cellular damage and promote the functions of immune cells.

  20. September 2016 Bayou Choctaw Subsidence Report

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, Dylan Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lord, Anna C. Snider [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    Subsidence monitoring is a crucial component to understanding cavern integrity of salt storage caverns. This report looks at historical and current data at the Bayou Choctaw Strategic Petroleum Reserve Site. Data from the most recent land-based annual surveys, GPS, and tiltmeter indicate the subsidence rates across the site are approximately 0.0 ft./yr. Because of this, there is no evidence from the subsidence survey to suggest any of the DOE caverns have been structurally compromised.

  1. Integrated Hatchery Operations Team: Policies and Procedures for Columbia Basin Anadromous Salmonid Hatcheries, 1994 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Integrated Hatchery Operations Team (Northwest Power Planning Council, Portland, OR)

    1995-01-01

    This document outlines regional policies and procedures for hatchery operations in the Columbia River Basin. The purpose of these policies is to provide regional guidelines by which all anadromous fish hatcheries will be operated. These policies will be adopted by the fisheries co-managers, and will provide guidance to operate hatcheries in an efficient and biologically sound manner. The hatchery policies presented in this manual are not intended to establish production priorities. Rather, the intent is to guide hatchery operations once production numbers are established. Hatchery operations discussed in this report include broodstock collection, spawning, incubation of eggs, fish rearing and feeding, fish release, equipment maintenance and operations, and personnel training. Decisions regarding production priorities must be provided by fishery managers through a comprehensive plan that addresses both natural and hatchery fish production. The Integrated Hatchery Operations Team is a multi-agency group called for by the Northwest Power Planning Council. This team was directed to develop new basinwide policies for managing and operating all existing and future anadromous fish hatcheries in the Columbia River Basin. The parties pledge to confer with each other and to use their authorities and resources to accomplish these mutually acceptable hatchery practices.

  2. Integrated Computer-Enhanced Remote Viewing System. Quarterly report number 4, July--October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-30

    The Interactive, Computer-Enhanced, Remote Viewing System (ICERVS) is a system designed to provide a reliable geometric description of a robotic task space in a fashion that enables robotic remediation to be carried out more efficiently and economically than with present systems. The key elements are a faithful way to store empirical data and a friendly user interface that provides an operator with timely access to all that is known about a scene. The development of ICERVS is to occur in three phases. Phase 1 will focus on the development of the Data Library, which contains the geometric data about the task space and the objects in it, and the Toolkit, which includes the mechanisms for manipulating and displaying both empirical and model data. Phase 2 will concentrate on integrating these subsystems with a sensor subsystem into one working system. Some additional functionality will be incorporated in the Data Library and Toolkit subsystems. Phase 3 will expand the configuration to meet the needs of a full scale demonstration of the interactive mapping of some waste site to be identified. The second Phase of the ICERVS project consists of nine tasks. Significant efforts were devoted to the completion of Task 1: Intermediate System Design, and Task 3: Computer Upgrade. This report describes progress in these two tasks.

  3. Report on FY17 testing in support of integrated EPP-SMT design methods development

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yanli . [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Jetter, Robert I. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sham, T. -L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-08-01

    The goal of the proposed integrated Elastic Perfectly-Plastic (EPP) and Simplified Model Test (SMT) methodology is to incorporate a SMT data-based approach for creep-fatigue damage evaluation into the EPP methodology to avoid the separate evaluation of creep and fatigue damage and eliminate the requirement for stress classification in current methods; thus greatly simplifying evaluation of elevated temperature cyclic service. The purpose of this methodology is to minimize over-conservatism while properly accounting for localized defects and stress risers. To support the implementation of the proposed methodology and to verify the applicability of the code rules, thermomechanical tests continued in FY17. This report presents the recent test results for Type 1 SMT specimens on Alloy 617 with long hold times, pressurization SMT on Alloy 617, and two-bar thermal ratcheting test results on SS316H at the temperature range of 405 °C to 705 °C. Preliminary EPP strain range analysis on the two-bar tests are critically evaluated and compared with the experimental results.

  4. MHD Integrated Topping Cycle Project. Fourteenth quarterly technical progress report, November 1, 1990-- January 31, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-02-01

    This fourteenth quarterly technical progress report of the MHD Integrated Topping Cycle Project presents the accomplishments during the period November 1, 1990 to January 31, 1991. Testing of the High Pressure Cooling Subsystem electrical isolator was completed. The PEEK material successfully passed the high temperature, high pressure duration tests (50 hours). The Combustion Subsystem drawings were CADAM released. The procurement process is in progress. An equipment specification and RFP were prepared for the new Low Pressure Cooling System (LPCS) and released for quotation. Work has been conducted on confirmation tests leading to final gas-side designs and studies to assist in channel fabrication.The final cathode gas-side design and the proposed gas-side designs of the anode and sidewall are presented. Anode confirmation tests and related analyses of anode wear mechanisms used in the selection of the proposed anode design are presented. Sidewall confirmation tests, which were used to select the proposed gas-side design, were conducted. The design for the full scale CDIF system was completed. A test program was initiated to investigate the practicality of using Avco current controls for current consolidation in the power takeoff (PTO) regions and to determine the cause of past current consolidation failures. Another important activity was the installation of 1A4-style coupons in the 1A1 channel. A description of the coupons and their location with 1A1 channel is presented herein.

  5. Study report recommendations for the next generation Range Safety System (RSS) Integrated Receiver/Decoder (IRD)

    Science.gov (United States)

    Crosby, Robert H.

    1992-01-01

    The Integrated Receiver/Decoder (IRD) currently used on the Space Shuttle was designed in the 1980 and prior time frame. Over the past 12 years, several parts have become obsolete or difficult to obtain. As directed by the Marshall Space Flight Center, a primary objective is to investigate updating the IRD design using the latest technology subsystems. To take advantage of experience with the current designs, an analysis of failures and a review of discrepancy reports, material review board actions, scrap, etc. are given. A recommended new design designated as the Advanced Receiver/Decoder (ARD) is presented. This design uses the latest technology components to simplify circuits, improve performance, reduce size and cost, and improve reliability. A self-test command is recommended that can improve and simplify operational procedures. Here, the new design is contrasted with the old. Possible simplification of the total Range Safety System is discussed, as is a single-step crypto technique that can improve and simplify operational procedures.

  6. Body integrity identity disorder crosses culture: case reports in the Japanese and Chinese literature.

    Science.gov (United States)

    Blom, Rianne M; Vulink, Nienke C; van der Wal, Sija J; Nakamae, Takashi; Tan, Zhonglin; Derks, Eske M; Denys, Damiaan

    2016-01-01

    Body integrity identity disorder (BIID) is a condition in which people do not perceive a part of their body as their own, which results in a strong desire for amputation or paralyzation. The disorder is likely to be congenital due to its very early onset. The English literature describes only Western patients with BIID, suggesting that the disorder might be merely prevalent in the West. To scrutinize this assumption, and to extend our knowledge of the etiology of BIID, it is important to trace cases with BIID in non-Western populations. Our objective was to review Chinese and Japanese literature on BIID to learn about its presence in populations with a different genetic background. A systematic literature search was performed in databases containing Japanese and Chinese research, published in the respective languages. Five Japanese articles of BIID were identified which described two cases of BIID, whereas in the Chinese databases only BIID-related conditions were found. This article reports some preliminary evidence that BIID is also present in non-Western countries. However, making general statements about the biological background of the disorder is hampered by the extremely low number of cases found. This low number possibly resulted from the extreme secrecy associated with the disorder, perhaps even more so in Asian countries.

  7. Sustainable Development Compromise[d] in the Planning of Metro Vancouver’s Agricultural Lands—the Jackson Farm Case

    Directory of Open Access Journals (Sweden)

    Meg Holden

    2013-11-01

    Full Text Available This research provides analysis of the case of the Jackson Farm development application, embedded within the particular dynamics of the municipal, regional, and provincial sustainability land use policy culture of the Metro Vancouver region, in Canada. Within a culture of appreciation of the increasing need for sustainability in land use policy, including the protection of agricultural lands at the provincial level through the Agricultural Land Reserve (ALR, to urban intensification and protection of the green zone at the regional scale, lies a political conflict that comes into focus in individual land use decisions, within municipalities struggling for autonomy. This case is neither driven strictly by “the politics of the highest bidder” nor by policy failure; the case of the Jackson Farm is instead a case of the challenges of implementing inter-governmental coordination and collaborative governance in a context of both significant sustainability policy and urban growth. The process can be seen to follow an ecological modernization agenda, seeking “win–win” alternatives rather than recognizing that typical compromises, over time, may tip the direction of development away from sustainability policy goals. Understanding the twists, turns, and eventual compromise reached in the case of the Jackson Farm brings to light the implications of the shift in the regional planning culture which may necessitate a less flexible, more structured prioritization of competing goals within plans and policies in order to meet sustainability goals. We highlight this, and present an alternative implementation process within the existing policy regime with potential to aid the specific goal of agricultural land protection.

  8. Compromised Prefrontal Cognitive Control Over Emotional Interference in Adolescents with Internet Gaming Disorder.

    Science.gov (United States)

    Lee, Junghan; Lee, Seojung; Chun, Ji Won; Cho, Hyun; Kim, Dai-jin; Jung, Young-Chul

    2015-11-01

    Increased reports of impulsivity and aggression in male adolescents with Internet gaming might reflect their dysfunction in emotion regulation, particularly in suppression of negative emotions, which should affect the various stages of Internet gaming disorder. This study tested the hypothesis that adolescents with Internet gaming disorder would be more disturbed by the emotional interference and demonstrate compromised dorsal anterior cingulate cortex (dACC) activation during a Stroop Match-to-Sample task. In addition, functional connectivity analysis was conducted to examine the interplays between neural correlates involved in emotional processing and how they were altered in adolescents with Internet gaming disorder. The Internet gaming disorder group demonstrated weaker dACC activation and stronger insular activations to interfering angry facial stimuli compared with the healthy control group. Negative functional connectivity between stronger insular activation and weaker dorsolateral prefrontal activation correlated with higher cognitive impulsivity in adolescents with Internet gaming disorder. These findings provide evidence of the compromised prefrontal cognitive control over emotional interference in adolescents with Internet gaming disorder.

  9. Conference report for the Atlantic Canada Opportunities Agency (ACOA) : wind integration in the North East : addressing wind integration issues in north eastern North America

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-03-27

    This conference report prepared for the Atlantic Canada Opportunities Agency (ACOA) contains a summary of the presentations which addressed wind integration issues facing northeastern North America. The region of northeastern North America encompasses New Brunswick, Newfoundland and Labrador, Nova Scotia, Prince Edward Island, Quebec, Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island and Vermont. Wind generation, load and transmission issues associated with wind integration in the region were discussed, including those that inhibit the transmission of wind; actions that will improve the integration of wind; and the process that could facilitate the uptake of wind. The conference reviewed key drivers behind wind industry growth; system operator capabilities; the European experience of wind integration; technology drivers; forecasting; balancing; and transmission planning, cost allocation and regulation. Advanced grid options and wind turbine generator products designed to solve grid connection problems were reviewed with reference to tools currently being designed to improve wind power plant performance and grid compliance. Developments within various independent system operators were reviewed along with governmental transmission entities and interconnection requirements for wind power plants. 38 refs., 17 figs., 2 appendices.

  10. Factors Affecting Preparers’ and Auditors’ Judgements about Materiality and Conciseness in Integrated Reporting

    NARCIS (Netherlands)

    Wee, M.; Tarca, A.; Krug, L.; Aerts, Walter; Pink, P.; Tilling, M.

    This report provides timely evidence about emerging practice among corporate report preparers around the world in determining materiality and achieving conciseness. It investigates how corporate report preparers make decisions about what to report with reference to the International Framework,

  11. Description of the HIA line in the CEEH integrated modelling chain. CEEH scientific report no. 5

    Energy Technology Data Exchange (ETDEWEB)

    Meulengracht Flachs, E. [Univ. of Southern Denmark (SDU), Odense (Denmark); Boenloekke, J.H.; Sigsgaard, T. [Aarhus Universitet, Aarhus (Denmark)] [and others

    2012-11-01

    The purpose of this report is to describe the different components constituting the HIA-line in the CEEH integrated energy-environment-health-cost modelling. The CEEH framework consists of a number of independent models linked together to assess the impacts and associated costs of emissions from energy production on human health. The HIA-line carries out assessment of the health impact and associated costs of human exposure to air pollution from future scenarios for energy production in Denmark. The methodology employed is the impact pathway, where future emissions from all Danish air pollution sources are modelled in the Balmorel model; the emitted air pollution is then dispersed and chemically transformed in time and space by either the NERI or the DMI Atmospheric Chemical Transport models. The resulting concentration fields of air pollution are then averaged to give municipality based levels, and the resulting health impact and associated societal cost of the Danish population is modelled in the Health Impact Assessment model. The social costs associated with air pollution exposure are then converted from the modelled exposure costs to emission costs to be fed into the Balmorel model as additional energy production costs. The CEEH HIA-line presents a novel way of modelling health related consequences of air pollution, as it directly models, the demography, air pollution, morbidity and mortality, in a dynamic and integrated setup. When modelling the health impact of Danish emitted air pollution in the period from 2005 to 2030 we find 2,000 extra deaths of lung cancer, 3,950 deaths of heart disease, 7,375 deaths of stroke and 1,750 deaths of COPD, and 11.475 premature deaths, amounting to 163,075 lost life years in the modelled 25-year period. The health related social costs sums up to 60.8m Euro for lung cancer, 88.3m Euro for heart disease, 91.6m Euro for stroke, 18.7m Euro for COPD, 26.9m Euro for other cause mortality and in total 282.5m Euro throughout the

  12. Modelling of Operative Report Documents for Data Integration into an openEHR-Based Enterprise Data Warehouse.

    Science.gov (United States)

    Haarbrandt, Birger; Wilschko, Andreas; Marschollek, Michael

    2016-01-01

    In order to integrate operative report documents from two operating room management systems into a data warehouse, we investigated the application of the two-level modelling approach of openEHR to create a shared data model. Based on the systems' analyses, a template consisting of 13 archetypes has been developed. Of these 13 archetypes, 3 have been obtained from the international archetype repository of the openEHR foundation. The remaining 10 archetypes have been newly created. The template was evaluated by an application system expert and through conducting a first test mapping of real-world data from one of the systems. The evaluation showed that by using the two-level modelling approach of openEHR, we succeeded to represent an integrated and shared information model for operative report documents. More research is needed to learn about the limitations of this approach in other data integration scenarios.

  13. SAMBA RECEPTION DESK: COMPROMISING AESTHETICS, FABRICATION AND STRUCTURAL PERFORMANCE WITH THE USE OF VIRTUAL AND PHYSICAL MODELS IN THE DESIGN PROCESS

    OpenAIRE

    Wilson Barbosa Neto; André Araujo; Guilherme Carvalho; Gabriela Celani

    2014-01-01

    The present paper describes an integrative design experiment in which different types of models were used in order to achieve a design that compromises aesthetics, lightness, fabrication, assembly and structural performance. It shows how an integrative aproach, through the use of both virtual and physical models, can provide valuable feedback in different phases of the design and fabrication process. It was possible to conclude that the design method used allowed solving many problems and had...

  14. Burst suppression on amplitude-integrated electroencephalogram may be induced by midazolam : a report on three cases

    NARCIS (Netherlands)

    ter Horst, HJ; Brouwer, OF; Bos, AF

    2004-01-01

    Continuous amplitude-integrated electroencephalogram (aEEG) recording with a cerebral function monitor is a useful tool to evaluate prognoses following perinatal asphyxia in term infants. Drugs may change the pattern of the conventional EEG. This report presents three infants treated with midazolam

  15. Burst suppression on amplitude-integrated electroencephalogram may be induced by midazolam : a report on three cases

    NARCIS (Netherlands)

    ter Horst, HJ; Brouwer, OF; Bos, AF

    Continuous amplitude-integrated electroencephalogram (aEEG) recording with a cerebral function monitor is a useful tool to evaluate prognoses following perinatal asphyxia in term infants. Drugs may change the pattern of the conventional EEG. This report presents three infants treated with midazolam

  16. The application of state-level integration of safeguards in Sweden. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Dahlin, G.; Haeggblom, E.; Larsson, Mats; Rehn, I

    2000-12-01

    The role of Sweden in disarmament and non-proliferation efforts extends from the late 1940's to the present. It covers active support to place nuclear weapons under international control and participation in practically all control regimes aimed at non-proliferation and elimination of any mass destruction capability. Sweden has also made available highly competent and high-ranking officers to serve many of the institutions and organisations supporting the political work and operative functions in this field. Until 1968, Sweden had a double-track policy where both the nuclear weapons option and non-proliferation as a possibility were pursued and investigated. After 1968, non-proliferation became the established policy, and the nuclear programme, materials and activities have since served exclusively peaceful purposes. It appears possible that the IAEA could, after a short period of initial implementation, be in a position to draw conclusions on the absence of undeclared nuclear materials and activities in Sweden. Sweden has undertaken to ensure the transparency of its nuclear programme by providing all relevant information and by facilitating physical access, as necessary, and by addressing any questions and issues of concern in a direct and open-minded manner. The implementation of traditional safeguards should continue effectively, to enable the Agency to draw its conclusions on the absence of diversion of declared nuclear material in Sweden in the future. Using its reporting mechanisms, the Agency should share these conclusions with Member States so as to ensure that the objectives of the strengthened safeguards are met. Under these conditions, IAEA could and would decide to proceed with the implementation of integrated safeguard measures at the declared facilities and locations in Sweden. It is proposed that IAEA would participate in annual PIV's, but would, however, detach from routine verification work to the extent possible and make full use of the

  17. Report on GeoData 2011 Workshop - Data Life Cycle, Integration and Citation

    Science.gov (United States)

    Signell, R.; Fox, P.

    2012-04-01

    The U.S. GeoData 2011 was inspired by a joint NSF-USGS identification of the need to hear from the broader 'geo' community on a variety of data related matters. While increasing attention needed to be paid to full life cycle of data, in the process of preparing and scoping the workshop two other hot issues were identified: integration and citation, giving the workshop three subject areas to delve into as well as to explore connections among them. Invited participants were drawn from all 'Geo' disciplines, and beyond, from information, computer and library science, from academia, agency and commercial organizations, and from student to senior faculty/ administrators. The workshop diversity provided a rich exchange of ideas, experiences and challenges for GeoData. Many key findings and recommendations have been extracted from the detail breakout discussions and syntheses during and after the workshop. Topical categories included: metadata, standards, standards-based tools, culture, collaboration and workforce. Key points that cut across all three-subject areas were: - A shift is needed within agencies to provide longer-term funding support, for communities to come together, remain coherent and to enable data stewardship, integration and citation within their communities and across to other communities (to the extent possible). - Agencies like USGS, NASA and NOAA must also play a key role in sustaining geoscience cyberinfrastructure by moving research advances into operations. - Community-wide standards and practices should build from demonstrated successes, be widely disseminated, and tools need to be developed to support them. - Education is critical to broader adoption. Marketing studies need to be conducted to provide the business case for full stewardship, integration and citation, and incentives are needed to encourage everyone to participate in making data integratable, citable, etc. While technology gaps are still evident across the three topic areas, there is

  18. Daniel Deronda: George Eliot’s Victorian Compromise

    Directory of Open Access Journals (Sweden)

    Ahmed Kahky

    2012-06-01

    Full Text Available Eventually, it seems Mrs. Lewes thought of re-emigrating the surplus of Jewish denizens in England to some exotic land in the East as a measure of freeing the English people from the inconvenience they complain of, the same way she and her illegal spouse thought of sending his sons to Natal in South Africa to free themselves from the any inconvenience at home. In other words, this was the Victorian compromise of the Jewish surplus at a time of extreme chauvinism and expanding imperialism.  Thus, the ideological background of Daniel Deronda represents the confluence—and compromise—between the ideological trends of imperialism and Zionism according to which the first creates, supports, and maintains the latter for its colonialist purposes. In fact, George Eliot’s indifference to the “rights and dignities” of the native, historical, and generational inhabitants of the land of Palestine resulted in the world’s gravest crime against humanity.

  19. Physiologic assessment of fetal compromise: biomarkers of toxic exposure

    Energy Technology Data Exchange (ETDEWEB)

    Longo, L.D.

    1987-10-01

    Understanding the physiologic and endocrinologic basis of fetal development is a major goal of perinatal biology. During the past decade a number of technological developments have allowed more precise evaluation of the fetus in utero and diagnosis of abnormalities. Despite these methodological achievements, however, there are no specific biological markers currently available to indicate that exposure to a given xenobiotic is associated with a cellular, subcellular, or pharmacodynamic event. This paper evaluates the following issues: what are some of the unique physiologic and endocrinologic features of the fetal milieu interieur. What problems are peculiar to fetal assessment. What are some examples of validated biomarkers and their applicability. What promising biomarkers are on the horizon. How may molecular probes be of value as biological markers of fetal compromise. What are some of the major research gaps and needs, and how should research priorities be set. Some of these topics are addressed. Moreover, the more general role(s) that various diagnostic methods and biological markers can have in an understanding of the regulation of fetal growth and differentiation and the role of xenobiotics in affecting the normal course of events are discussed.

  20. Protection characteristics of a Faraday cage compromised by lightning burnthrough.

    Energy Technology Data Exchange (ETDEWEB)

    Warne, Larry Kevin; Bystrom, Edward; Jorgenson, Roy Eberhardt; Montoya, Sandra L.; Merewether, Kimball O.; Coats, Rebecca Sue; Martinez, Leonard E.; Jojola, John M.

    2012-01-01

    A lightning flash consists of multiple, high-amplitude but short duration return strokes. Between the return strokes is a lower amplitude, continuing current which flows for longer duration. If the walls of a Faraday cage are made of thin enough metal, the continuing current can melt a hole through the metal in a process called burnthrough. A subsequent return stroke can couple energy through this newly-formed hole. This LDRD is a study of the protection provided by a Faraday cage when it has been compromised by burnthrough. We initially repeated some previous experiments and expanded on them in terms of scope and diagnostics to form a knowledge baseline of the coupling phenomena. We then used a combination of experiment, analysis and numerical modeling to study four coupling mechanisms: indirect electric field coupling, indirect magnetic field coupling, conduction through plasma and breakdown through the hole. We discovered voltages higher than those encountered in the previous set of experiments (on the order of several hundreds of volts).

  1. Compromised Rat Testicular Antioxidant Defence System by Hypothyroidism before Puberty

    Directory of Open Access Journals (Sweden)

    Dipak K. Sahoo

    2012-01-01

    Full Text Available Altered thyroid function during early stages of development is known to affect adversely testicular growth, physiology, and antioxidant defence status at adulthood. The objective of the present study is to investigate the modulation of antioxidant defence status in neonatal persistent hypothyroid rats before their sexual maturation and also to identify the specific testicular cell populations vulnerable to degeneration during neonatal hypothyroidism in immature rats. Hypothyroidism was induced in neonates by feeding the lactating mother with 0.05% 6-n-propyl-2-thiouracil (PTU through the drinking water. From the day of parturition till weaning (25 day postpartum, the pups received PTU through mother's milk (or drinking water and then directly from drinking water containing PTU for the remaining period of experimentation. On the 31st day postpartum, the animals were sacrificed for the study. An altered antioxidant defence system marked by elevated SOD, CAT, and GR activities, with decreased GPx and GST activities were observed along with increased protein carbonylation, disturbed redox status in hypothyroid immature rat testis. This compromised testicular antioxidant status might have contributed to poor growth and development by affecting the spermatogenesis and steroidogenesis in rats before puberty as indicated by reduced germ cell number, complete absence of round spermatids, decreased seminiferous tubule diameter, and decreased testosterone level.

  2. Loss of the nuclear receptor corepressor SLIRP compromises male fertility.

    Directory of Open Access Journals (Sweden)

    Shane M Colley

    Full Text Available Nuclear receptors (NRs and their coregulators play fundamental roles in initiating and directing gene expression influencing mammalian reproduction, development and metabolism. SRA stem Loop Interacting RNA-binding Protein (SLIRP is a Steroid receptor RNA Activator (SRA RNA-binding protein that is a potent repressor of NR activity. SLIRP is present in complexes associated with NR target genes in the nucleus; however, it is also abundant in mitochondria where it affects mitochondrial mRNA transcription and energy turnover. In further characterisation studies, we observed SLIRP protein in the testis where its localization pattern changes from mitochondrial in diploid cells to peri-acrosomal and the tail in mature sperm. To investigate the in vivo effects of SLIRP, we generated a SLIRP knockout (KO mouse. This animal is viable, but sub-fertile. Specifically, when homozygous KO males are crossed with wild type (WT females the resultant average litter size is reduced by approximately one third compared with those produced by WT males and females. Further, SLIRP KO mice produced significantly fewer progressively motile sperm than WT animals. Electron microscopy identified disruption of the mid-piece/annulus junction in homozygous KO sperm and altered mitochondrial morphology. In sum, our data implicates SLIRP in regulating male fertility, wherein its loss results in asthenozoospermia associated with compromised sperm structure and mitochondrial morphology.

  3. Towards mesoscience the principle of compromise in competition

    CERN Document Server

    Li, Jinghai

    2014-01-01

    This brief is devoted to providing a complete outline of meso-science by briefing the relevant contents from the published book and by updating evidences and concepts of meso-science. The importance of meso-science in solving various problems in energy, resource, and the environment is introduced.  The whole evolutionary development of the EMMS principle is reviewed to show how a simple idea on the customized modeling of particle clustering in gas-solid systems was developed, verified, extended, and finally generalized into the common principle of compromise in competition between dominant mechanisms for all mesoscale phenomena in science and engineering, leading to the proposition of meso-science. More importantly, updates on the concept of meso-science and perspectives are presented, along with new insights and findings from after the publication of the original book. In this way, we hope to help readers more easily familiarize themselves with meso-science, and to trigger interest and attention to this int...

  4. Evaluation of intravenous voriconazole in patients with compromised renal function

    Directory of Open Access Journals (Sweden)

    Lilly Craig M

    2013-01-01

    Full Text Available Abstract Background Incorporation of the solubilizing excipient, sulfobutylether-β-cyclodextrin (SBECD, in the intravenous (IV formulation of voriconazole has resulted in the recommendation that this formulation be used with caution in patients with creatinine clearances (Clcr  Methods A total of 128 patients aged 11–93 years who had a baseline Clcr cr and Clcr levels while on therapy were compared with baseline values and between groups. Results The groups had similar characteristics apart from the larger proportion of females that received fluconazole. Baseline Scr was higher in those receiving caspofungin, but maximal increases of Scr and decreases in Clcr were greatest for the fluconazole group. Acute kidney injury (AKI, assessed by RIFLE criteria, was more frequent in the fluconazole vs. the caspofungin group (p  Conclusions Treatment of fungal infections in patients with compromised renal function with an SBECD-containing antifungal agent was not associated with AKI in clinical practice. Since the infecting organism was associated with AKI, decision on which antifungal to use should be determined by susceptibilities to the organism and not the incorporation of SBECD in the IV formulation.

  5. Metabolic Stress and Compromised Identity of Pancreatic Beta Cells

    Science.gov (United States)

    Swisa, Avital; Glaser, Benjamin; Dor, Yuval

    2017-01-01

    Beta cell failure is a central feature of type 2 diabetes (T2D), but the molecular underpinnings of the process remain only partly understood. It has been suggested that beta cell failure in T2D involves massive cell death. Other studies ascribe beta cell failure to cell exhaustion, due to chronic oxidative or endoplasmic reticulum stress leading to cellular dysfunction. More recently it was proposed that beta cells in T2D may lose their differentiated identity, possibly even gaining features of other islet cell types. The loss of beta cell identity appears to be driven by glucotoxicity inhibiting the activity of key beta cell transcription factors including Pdx1, Nkx6.1, MafA and Pax6, thereby silencing beta cell genes and derepressing alternative islet cell genes. The loss of beta cell identity is at least partly reversible upon normalization of glycemia, with implications for the reversibility of T2D, although it is not known if beta cell failure reaches eventually a point of no return. In this review we discuss current evidence for metabolism-driven compromised beta cell identity, key knowledge gaps and opportunities for utility in the treatment of T2D.

  6. Oviposition site selection in Cactoblastis cactorum (Lepidoptera): constraints and compromises.

    Science.gov (United States)

    Robertson, H G

    1987-10-01

    Oviposition by Cactoblastis cactorum on Opuntia ficus-indica and O. aurantiaca was assessed from the positioning of egg sticks on plants in the field. The number of egg sticks laid on O. ficus-indica plants was affected by: (1) plant size; (2) moth emergence near the plant; (3) cladode condition; and (4) plant conspicuousness. These factors contributed towards the clumping of egg sticks on plants. There was no apparent oviposition preference for one of the two host plant species despite the fact that egg predation was higher and fecundity lower on O. aurantiaca. The selection of a site for oviposition on the host plants was influenced by: (1) cladode condition; (2) height above ground; and (3) shelter from wind during oviposition. Succulent cladodes were the favoured sites for oviposition. The evidence suggests that in C. cactorum, oviposition site selection is largely the net result of a compromise between oviposition behaviour selected for increasing the probability of juvenile survival and oviposition behaviour selected for increasing the probability of laying the full complement of eggs. In addition, environmental and physiological factors such as wind and wing-loading, are thought to place constraints on the range of sites available for oviposition.

  7. Low-Cost Solar Array Project. Progress report 12, January-April 1979 and proceedings of the 12th Project Integration Meeting

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    This report describes progress made by the Low-Cost Solar Array Project during the period January through April 1979. It includes reports on project analysis and integration; technology development in silicon material, large-area sheet silicon, and encapsulation; production process and equipment development; engineering and operations, and a discussion of the steps taken to integrate these efforts. It includes a report on, and copies of viewgraphs presented at the Project Integration Meeting held April 4-5, 1979.

  8. Integrating Computers into the Accounting Curriculum Using an IBM PC Network. Final Report.

    Science.gov (United States)

    Shaoul, Jean

    Noting the increased use of microcomputers in commerce and the accounting profession, the Department of Accounting and Finance at the University of Manchester recognized the importance of integrating microcomputers into the accounting curriculum and requested and received a grant to develop an integrated study environment in which students would…

  9. Educational Planning Methodology for the Integrated Development of Rural Areas. Reports Studies... S.83.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    A summary of educational planning methodologies tested in Argentina, Guatemala, Brazil, Ecuador, and Bolivia, the document offers opinions and proposals about integrated rural development. Integrated rural development is seen as a social, economic, political, and cultural process in rural areas, designed to improve living conditions. Chapters…

  10. Integrated Research on Midwestern Landscape Change: A Program Description and Progress Report

    Science.gov (United States)

    Paul H. Gobster; Robert G. Haight; David S. Shriner

    2000-01-01

    The USDA Forest Service North Central Research Station has embarked on a new integrated research and development program to identify and understand the development-related aspects of Midwestern landscape change. This paper describes the framework and scope of the Landscape Change Integrated Program and highlights projects begun during the first two years. Partnerships...

  11. Nationwide Report on the Findings of Integrated School Health Screening Program in Iran

    Directory of Open Access Journals (Sweden)

    P Poursafa

    2010-06-01

    Full Text Available Background: Screening of students´ health problems could lead to timely prevention and control of many health disorders. This study aimed to determine the nationwide prevalence of common disorders through school health screening program in Iran Methods: This cross-sectional national screening program was conducted in 2007-2008 among first- and third-grade- students in primary schools, first- grade-students of middle and high schools of all provinces in Iran.Results: Data were obtained from 3,124,021 (81.9% students reported from the whole country classified into 33 geographical zones. Of total students studied, 12.48% had weight abnormalities, 4.77% had visual disorders, 3.95 % had head lice, 2.24% had behavioral disorders, and 0.6% had hearing disorders. Among students studied, 0.4%, 0.7%, 0.4% and0.8% had endocrine, psychological, neurological and genitourinary disorders, respectively. In addition, 2.1%, 1.9%, 1.8%, 0.8%0.5%, 0.3% and 0.3% of students had ear, nose & pharynx disorder, anemia ,skin & hair , cardiac ,abdominal, vertebral and lung problems, respectively. In elementary schools;57.6% of first-grade- students with at least one disorder were managed in outpatient settings and 6% of them were hospitalized for more investigation. Among third- grade- students of elementary schools, these values corresponded to 13.2% and 1.1%, respectively. Among first grade students of middle and high schools, this prevalence was 58.5% and 44.6% and 1.2% and 0.3% of students were hospitalized for more investigation.Conclusion: This integrated school screening program revealed a considerably high prevalence of health disorders among school students. These results might help health policy makers to design future health promoting programs.

  12. Heat pump centered integrated community energy systems: system development. Georgia Institute of Technology final report

    Energy Technology Data Exchange (ETDEWEB)

    Wade, D.W.; Trammell, B.C.; Dixit, B.S.; McCurry, D.C.; Rindt, B.A.

    1979-12-01

    Heat Pump Centered-Integrated Community Energy Systems (HP-ICES) show the promise of utilizing low-grade thermal energy for low-quality energy requirements such as space heating and cooling. The Heat Pump - Wastewater Heat Recovery (HP-WHR) scheme is one approach to an HP-ICES that proposes to reclaim low-grade thermal energy from a community's wastewater effluent. This report develops the concept of an HP-WHR system, evaluates the potential performance and economics of such a system, and examines the potential for application. A thermodynamic performance analysis of a hypothetical system projects an overall system Coefficient of Performance (C.O.P.) of from 2.181 to 2.264 for waste-water temperatures varying from 50/sup 0/F to 80/sup 0/F. Primary energy source savings from the nationwide implementation of this system is projected to be 6.0 QUADS-fuel oil, or 8.5 QUADS - natural gas, or 29.7 QUADS - coal for the period 1980 to 2000, depending upon the type and mix of conventional space conditioning systems which could be displaced with the HP-WHR system. Site-specific HP-WHR system designs are presented for two application communities in Georgia. Performance analyses for these systems project annual cycle system C.O.P.'s of 2.049 and 2.519. Economic analysis on the basis of a life cycle cost comparison shows one site-specific system design to be cost competitive in the immediate market with conventional residential and light commercial HVAC systems. The second site-specific system design is shown through a similar economic analysis to be more costly than conventional systems due mainly to the current low energy costs for natural gas. It is anticipated that, as energy costs escalate, this HP-WHR system will also approach the threshold of economic viability.

  13. W-026 acceptance test report system integration equipment (SIE)(submittal {number_sign} 018.6.A)

    Energy Technology Data Exchange (ETDEWEB)

    Watson, T.L.

    1997-01-27

    Acceptance testing of the System Integration Equipment (SIE) at Hanford was performed in two stages. The first was inconclusive, and resulted in a number of findings. These finding. are summarized as part of this report. The second stage of testing addressed these findings, and performed full system testing per the approved test procedure. This report includes summaries of all testing, results and finding.. Although the SIE did not in some cases perform as required for plant operations, it did perform per the system specification. (These discrepancies were noted and are addressed elsewhere.) Following testing, the system was formaLLy accepted. Documentation of this acceptance is incLuded in this report.

  14. Moderate alcohol exposure compromises neural tube midline development in prenatal brain.

    Science.gov (United States)

    Zhou, Feng C; Sari, Youssef; Powrozek, Teresa; Goodlett, Charles R; Li, Ting-Kai

    2003-08-12

    We previously reported that fetal alcohol treatment compromised the development of the midline raphe and the serotonin neurons contained in it. In this study, we report that the timely development of midline neural tissue during neural tube formation is sensitive to alcohol exposure. Pregnant dams were treated from embryonic day 7 (E7, prior to neurulation) or E8.5 (at neurulation) with the following diets: (a) alcohol (ALC), given as either a 20% or 25% ethanol-derived calorie (EDC) liquid diet, or (b) isocaloric liquid diet pair-fed (PF), or (c) standard rat chow (Chow). Fetal brains from each group were examined on E13, E15, or E18. Neural tube development was compromised as a result of alcohol exposure in the following ways: (1) approximately 60% of embryos at E13 and 20% at E15 showed perforation of the floor plate in the diencephalic vesicle, (2) although completely closed at E13, 70-80% of embryos failed to complete the formation of neural tissue at the roof as the alcohol exposure continued to E15, and (3) 60-80% of embryos show delayed 'occlusion' of the ventral canal by newly formed nestin-positive neuroepithelial cells and S100beta-positive glia in the brainstem of E15. The compromised (incomplete) neural tube midline (cNTM) occurred near the ventricles at E13 and E15, but was later completed at E18. In all cases, the cNTM was accompanied by an enlarged ventricle, and dose-dependent brain weight reduction. The midline of the neural tube at the roof and floor plates is known to mediate timely trophic induction for neural differentiation. Prenatal midline deficits also have the potential to affect the development of midline neurons such as raphe, septal nuclei, and the timely crossing of commissural fibers. The results of the liquid diet alcohol exposure paradigm suggest it is more a model for Alcohol-Related Neurodevelopmental Disorder (ARND) featuring neuropsychiatric disorders than for full-blown fetal alcohol syndrome (FAS) with noticeable facial

  15. Esthetic Rehabilitation of a Severely Compromised Anterior Area: Combined Periodontal and Restorative Approach

    Directory of Open Access Journals (Sweden)

    Rachele Censi

    2014-01-01

    Full Text Available The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves a multidisciplinary approach that includes the change of both the morphological aspect of the teeth and the architecture of gum tissues. This clinical report describes a successful interdisciplinary approach for the treatment of an esthetically compromised dentition. In a first phase, the periodontal plastic surgery was performed for root coverage and, in particular, it was decided for the execution of a coronally advanced flap for the treatment of multiple recession defects. Once complete healing of soft tissues was obtained, six lithium disilicate veneers were placed over the anterior maxillary teeth. Lithium disilicate is a glass-based ceramic which presents excellent aesthetics and allows the passage of light without creating unnatural reflections. This feature has made it possible to recreate a natural aspect of teeth that in combination with the harmonic architecture of soft tissue has permitted obtaining a beautiful and pleasant smile.

  16. Esthetic rehabilitation of a severely compromised anterior area: combined periodontal and restorative approach.

    Science.gov (United States)

    Censi, Rachele; Vavassori, Virna; Borgonovo, Andrea Enrico; Re, Dino

    2014-01-01

    The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves a multidisciplinary approach that includes the change of both the morphological aspect of the teeth and the architecture of gum tissues. This clinical report describes a successful interdisciplinary approach for the treatment of an esthetically compromised dentition. In a first phase, the periodontal plastic surgery was performed for root coverage and, in particular, it was decided for the execution of a coronally advanced flap for the treatment of multiple recession defects. Once complete healing of soft tissues was obtained, six lithium disilicate veneers were placed over the anterior maxillary teeth. Lithium disilicate is a glass-based ceramic which presents excellent aesthetics and allows the passage of light without creating unnatural reflections. This feature has made it possible to recreate a natural aspect of teeth that in combination with the harmonic architecture of soft tissue has permitted obtaining a beautiful and pleasant smile.

  17. Managing the Technology Acquisition Integration Paradox at SAP

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Kude, Thomas; Popp, Karl Michael

    2016-01-01

    In this paper, we report on a novel approach developed by SAP AG, the German enterprise software company, for managing the integration of acquisitions of companies to access innovative technologies and related capabilities: the Product Council approach. The value of the Product Council approach...... rests in ensuring critical speed while not compromising accuracy in the integration process. For SAP, the Product Council became a vital component in its technology acquisition capability that allows the company to retain its technological edge in the hypercompetitive software industry....

  18. Managing the Technology Acquisition Integration Paradox at SAP

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Kude, Thomas; Popp, Karl Michael

    2016-01-01

    In this paper, we report on a novel approach developed by SAP AG, the German enterprise software company, for managing the integration of acquisitions of companies to access innovative technologies and related capabilities: the Product Council approach. The value of the Product Council approach...... rests in ensuring critical speed while not compromising accuracy in the integration process. For SAP, the Product Council became a vital component in its technology acquisition capability that allows the company to retain its technological edge in the hypercompetitive software industry....

  19. Systems Integration Using Web Services, REST and SOAP: A Practical Report

    Directory of Open Access Journals (Sweden)

    GARCIA, C. M.

    2017-06-01

    Full Text Available In companies environments, it is normal to exist several systems to ease daily activities. In academic environments, it also happens. However, academic environments may be even more heterogeneous as there are many specialized activities, such as: restaurant, library, academic processes, administrative processes and computer network services, such as email and network authentication. To maintain the data consistency throughout the systems, all the systems must be integrated. This integration was carried out in the Federal University of Lavras by using Simples Object Access Protocol (SOAP as communication protocol. The development of a new system (mobile application, it was noticed that SOAP is very CPU-intensive and slow, as mobile devices have constraints such as internet and processing. Thus, a REST-JSON layer to integrate mobile application and the integration architecture was developed, benefiting from all the resources the integration architecture had. By using this new layer, the offer of functions from the integration architecture was also expanded to REST, attending to other applications without having to make big changes in the code. It was measured that the REST-JSON layer consumes around 73% less data than SOAP. The REST-JSON layer was released, attending to about 5600 installations of the application that requests the integration around 54000 times a day.

  20. Idaho National Laboratory Integrated Safety Management System 2010 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Thomas J. Haney

    2010-12-01

    Idaho National Laboratory completes an annual Integrated Safety Management System effectiveness review per 48 CFR 970.5223-1 “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assesses ISMS effectiveness, provides feedback to maintain system integrity, and helps identify target areas for focused improvements and assessments for the following year. Using one of the three Department of Energy (DOE) descriptors in DOE M 450.4-1 regarding the state of ISMS effectiveness during Fiscal Year (FY) 2010, the information presented in this review shows that INL achieved “Effective Performance.”

  1. Efficacy of New Adhesion Promoters on Compromised Hypocalcified Enamel.

    Science.gov (United States)

    Vamsilatha, Kurapati; Venkata, Kishore Mayakuntla Sai; Aileni, Kaladhar Reddy; Sashidhar, Nagam Reddy

    2015-07-01

    The amount of technological progress occurred in the last few years has brought an add up to the benefits of bonding in Orthodontics. Research-based findings have constantly led to the development of new materials that are aimed to simplify the clinical procedures like bonding of brackets to compromised enamel surfaces. Hence, the present study is aimed to assess the bond strength of orthodontic brackets on fluorosed enamel using adhesion promoters. To evaluate the shear bond strength (SBS) of orthodontic brackets bonded on fluorosed enamel using conventional Transbond XT and new adhesion promoters such as Enhance LC and All Bond 3. The study involved 90 non carious, extracted teeth with mild to moderate fluorosis randomly divided into 3 Groups. In Group - I (control group) the teeth were bonded with conventional Transbond XT and cured with LED light. In Group - II Enhance LC was applied to fluorosed enamel before bonding and in Group - III All Bond 3 was used. Shear bond strength was tested by using Universal testing Instron machine. ANOVA and Post-Hoc Tukey's tests were used to compare shear bond strength. Adhesive remnant on the tooth was assessed and scored using adhesive remnant index (ARI). Results showed a reduced SBS values (9.43MPa ±3.03) with conventional Transbond XT on fluorosed enamel. Among the adhesion boosters used Enhance LC illustrated lesser SBS values (12.03 MPa ± 4.42) compared with All Bond 3 (14.38MPa ±4.92). ARI showed bond failure at bracket resin interface in group I & group II and at enamel resin interface in group III although statistically insignificant. It was concluded that using adhesion boosters on fluorosed enamel showed higher bond strength compared to the control group. Among the two adhesion promoters used All Bond 3 expressed highest bond strength compared to Enhance LC although statistically insignificant.

  2. Study of integration issues to realize OTEC market potential. First quarterly report. [134 references

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-12-01

    The specific objective of this study is to examine the commercialization of OTEC technology in the electric utility industry in the Gulf region of the United States. To accomplish this, the project staff is identifying the major issues that will arise in the integration of OTEC units into the power delivery systems in the Gulf Region. Among these issues are problems that must be resolved and barriers to be overcome. These are being identified and alternative approaches to resolving or overcoming them will be explored. Their relative importance in the integration will be assessed as well. The alternative approaches to resolving problems and overcoming barriers will be evaluated to determine their relative effectiveness, and the problems and barriers will be conceptually resolved. This evaluation will permit the recommendation of preferred approaches to integration and the preferred approaches will be assembled into a structured strategy for OTEC commercialization. A list of 134 references relevant to OTEC electric power plant integration issues is included.

  3. Montana Integrated Monitoring in Bird Conservation Regions: 2014 Field Implementation Report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In 2014 the Avian Science Center (ASC) at the University of Montana (UM) participated in the Integrated Monitoring in Bird Conservation Regions (IMBCR) program for a...

  4. Idaho National Laboratory Integrated Safety Management System 2011 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Farren Hunt

    2011-12-01

    Idaho National Laboratory (INL) performed an annual Integrated Safety Management System (ISMS) effectiveness review per 48 Code of Federal Regulations (CFR) 970.5223-1, 'Integration of Environment, Safety and Health into Work Planning and Execution.' The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and helped identify target areas for focused improvements and assessments for fiscal year (FY) 2012. The information presented in this review of FY 2011 shows that the INL has performed many corrective actions and improvement activities, which are starting to show some of the desired results. These corrective actions and improvement activities will continue to help change culture that will lead to better implementation of defined programs, resulting in moving the Laboratory's performance from the categorization of 'Needs Improvement' to the desired results of 'Effective Performance.'

  5. Design of Elastomer Structure to Facilitate Incorporation of Expanded Graphite in Silicones Without Compromising Electromechanical Integrity

    DEFF Research Database (Denmark)

    Hassouneh, Suzan Sager; Daugaard, Anders Egede; Skov, Anne Ladegaard

    2015-01-01

    The development of elastomer materials with a high dielectric permittivity has attracted increased interest over the past years due to their use in, for example, dielectric elastomers. For this particular use, both the electrically insulating properties - as well as the mechanical properties...... of the elastomer - have to be tightly controlled in order not to destroy favorable elastic properties by the addition of particles. This study focuses on improving the electromechanical properties of an enhanced PDMS matrix with expanded graphite (EG) as filler. The PDMS matrix is crosslinked by means of an 8...

  6. Loss of A-type lamin expression compromises nuclear envelope integrity in breast cancer

    Institute of Scientific and Technical Information of China (English)

    Callinice D. Capo-chichi; Kathy Q. Car; Jennifer Smedberg; Parvin Ganjei-Azar; Andrew K. Godwin; Xiang-Xi Xu

    2011-01-01

    Through advances in technology, the genetic basis of cancer has been investigated at the genomic level, and many fundamental questions have begun to be addressed. Among several key unresolved questions in cancer biology, the molecular basis for the link between nuclear deformation and malignancy has not been determined. Another hallmark of human cancer is aneuploidy; however, the causes and consequences of aneuploidy are unanswered and are hotly contested topics. We found that nuclear lamina proteins lamin A/C are absent in a significant fraction (38%) of human breast cancer tissues. Even in lamin A/C-positive breast cancer, lamin A/C expression is heterogeneous or aberrant (such as nonnuclear distribution) in the population of tumor cells, as determined by immunohistology and immunofluorescence microscopy. In most breast cancer cell lines, a significant fraction of the lamin A/Cnegative population was observed. To determine the consequences of the loss of lamin A/C, we suppressed their expression by shRNA in non-cancerous primary breast epithelial cells. Down-regulation of lamin A/C in breast epithelial cells led to morphological deformation, resembling that of cancer cells, as observed by immunofluorescence microscopy. The lamin A/C-suppressed breast epithelial cells developed aneuploidy as determined by both flow cytometry and fluorescence in situ hybridization. We conclude that the loss of nuclear envelope structural proteins lamin A/C in breast cancer underlies the two hallmarks of cancer aberrations in nuclear morphology and aneuploidy.

  7. The muscle-mechanical compromise framework: Implications for the scaling of gait and posture

    Directory of Open Access Journals (Sweden)

    Usherwood James Richard (Jim

    2016-09-01

    Full Text Available Many aspects of animal and human gait and posture cannot be predicted from purely mechanical work minimization or entirely based on optimizing muscle efficiency. Here, the Muscle-Mechanical Compromise Framework is introduced as a conceptual paradigm for considering the interactions and compromises between these two objectives. Current assumptions in implementing the Framework are presented. Implications of the compromise are discussed and related to the scaling of running mechanics and animal posture.

  8. Space station operations task force. Panel 3 report: User development and integration

    Science.gov (United States)

    1987-01-01

    The User Development and Integration Panel of the Space Station Operations Task Force was chartered to develop concepts relating to the operations of the Space Station manned base and the platforms, user accommodation and integration activities. The needs of the user community are addressed in the context with the mature operations phase of the Space Station. Issues addressed include space station pricing options, marketing strategies, payload selection and resource allocation options, and manifesting techniques.

  9. Technical Report: Toward a Scalable Algorithm to Compute High-Dimensional Integrals of Arbitrary Functions

    Energy Technology Data Exchange (ETDEWEB)

    Snyder, Abigail C. [University of Pittsburgh; Jiao, Yu [ORNL

    2010-10-01

    Neutron experiments at the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory (ORNL) frequently generate large amounts of data (on the order of 106-1012 data points). Hence, traditional data analysis tools run on a single CPU take too long to be practical and scientists are unable to efficiently analyze all data generated by experiments. Our goal is to develop a scalable algorithm to efficiently compute high-dimensional integrals of arbitrary functions. This algorithm can then be used to integrate the four-dimensional integrals that arise as part of modeling intensity from the experiments at the SNS. Here, three different one-dimensional numerical integration solvers from the GNU Scientific Library were modified and implemented to solve four-dimensional integrals. The results of these solvers on a final integrand provided by scientists at the SNS can be compared to the results of other methods, such as quasi-Monte Carlo methods, computing the same integral. A parallelized version of the most efficient method can allow scientists the opportunity to more effectively analyze all experimental data.

  10. Body integrity identity disorder crosses culture: case reports in the Japanese and Chinese literature

    Directory of Open Access Journals (Sweden)

    Blom RM

    2016-06-01

    Full Text Available Rianne M Blom,1 Nienke C Vulink,1 Sija J van der Wal,1 Takashi Nakamae,1–3 Zhonglin Tan,1,4 Eske M Derks,1 Damiaan Denys1,5 1Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; 2Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 3Department of Neural Computation for Decision-Making, ATR Brain Information Communication Research Laboratory Group, Kyoto, Japan; 4Department of Psychiatry, Hangzhou Mental Health Center, Hangzhou, People’s Republic of China; 5Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands Abstract: Body integrity identity disorder (BIID is a condition in which people do not perceive a part of their body as their own, which results in a strong desire for amputation or paralyzation. The disorder is likely to be congenital due to its very early onset. The English literature describes only Western patients with BIID, suggesting that the disorder might be merely prevalent in the West. To scrutinize this assumption, and to extend our knowledge of the etiology of BIID, it is important to trace cases with BIID in non-Western populations. Our objective was to review Chinese and Japanese literature on BIID to learn about its presence in populations with a different genetic background. A systematic literature search was performed in databases containing Japanese and Chinese research, published in the respective languages. Five Japanese articles of BIID were identified which described two cases of BIID, whereas in the Chinese databases only BIID-related conditions were found. This article reports some preliminary evidence that BIID is also present in non-Western countries. However, making general statements about the biological background of the disorder is hampered by the extremely low number of cases found. This low number possibly resulted from the extreme secrecy

  11. Evidence Report, Risk of Inadequate Design of Human and Automation/Robotic Integration

    Science.gov (United States)

    Zumbado, Jennifer Rochlis; Billman, Dorrit; Feary, Mike; Green, Collin

    2011-01-01

    The success of future exploration missions depends, even more than today, on effective integration of humans and technology (automation and robotics). This will not emerge by chance, but by design. Both crew and ground personnel will need to do more demanding tasks in more difficult conditions, amplifying the costs of poor design and the benefits of good design. This report has looked at the importance of good design and the risks from poor design from several perspectives: 1) If the relevant functions needed for a mission are not identified, then designs of technology and its use by humans are unlikely to be effective: critical functions will be missing and irrelevant functions will mislead or drain attention. 2) If functions are not distributed effectively among the (multiple) participating humans and automation/robotic systems, later design choices can do little to repair this: additional unnecessary coordination work may be introduced, workload may be redistributed to create problems, limited human attentional resources may be wasted, and the capabilities of both humans and technology underused. 3) If the design does not promote accurate understanding of the capabilities of the technology, the operators will not use the technology effectively: the system may be switched off in conditions where it would be effective, or used for tasks or in contexts where its effectiveness may be very limited. 4) If an ineffective interaction design is implemented and put into use, a wide range of problems can ensue. Many involve lack of transparency into the system: operators may be unable or find it very difficult to determine a) the current state and changes of state of the automation or robot, b) the current state and changes in state of the system being controlled or acted on, and c) what actions by human or by system had what effects. 5) If the human interfaces for operation and control of robotic agents are not designed to accommodate the unique points of view and

  12. Addressing System Integration Issues Required for the Developmente of Distributed Wind-Hydrogen Energy Systems: Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.D; Salehfar, H.; Harrison, K.W.; Dale, N.; Biaku, C.; Peters, A.J.; Hernandez-Pacheco: E.

    2008-04-01

    Wind generated electricity is a variable resource. Hydrogen can be generated as an energy storage media, but is costly. Advancements in power electronics and system integration are needed to make a viable system. Therefore, the long-term goal of the efforts at the University of North Dakota is to merge wind energy, hydrogen production, and fuel cells to bring emission-free and reliable power to commercial viability. The primary goals include 1) expand system models as a tool to investigate integration and control issues, 2) examine long-term effects of wind-electrolysis performance from a systematic perspective, and 3) collaborate with NREL and industrial partners to design, integrate, and quantify system improvements by implementing a single power electronics package to interface wild AC to PEM stack DC requirements. This report summarizes the accomplishments made during this project.

  13. Addressing System Integration Issues Required for the Developmente of Distributed Wind-Hydrogen Energy Systems: Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.D; Salehfar, H.; Harrison, K.W.; Dale, N.; Biaku, C.; Peters, A.J.; Hernandez-Pacheco: E.

    2008-04-01

    Wind generated electricity is a variable resource. Hydrogen can be generated as an energy storage media, but is costly. Advancements in power electronics and system integration are needed to make a viable system. Therefore, the long-term goal of the efforts at the University of North Dakota is to merge wind energy, hydrogen production, and fuel cells to bring emission-free and reliable power to commercial viability. The primary goals include 1) expand system models as a tool to investigate integration and control issues, 2) examine long-term effects of wind-electrolysis performance from a systematic perspective, and 3) collaborate with NREL and industrial partners to design, integrate, and quantify system improvements by implementing a single power electronics package to interface wild AC to PEM stack DC requirements. This report summarizes the accomplishments made during this project.

  14. Integrity assessment plan for PNL 300 area radioactive hazardous waste tank system. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The Pacific Northwest Laboratory (PNL), operated by Battelle Memorial Institute under contract to the U.S. Department of Energy, operates tank systems for the U.S. Department of Energy, Richland Operations Office (DOE-RL), that contain dangerous waste constituents as defined by Washington State Department of Ecology (WDOE) Dangerous Waste Regulations, Washington Administrative Code (WAC) 173-303-040(18). Chapter 173-303-640(2) of the WAC requires the performance of integrity assessments for each existing tank system that treats or stores dangerous waste, except those operating under interim status with compliant secondary containment. This Integrity Assessment Plan (IAP) identifies all tasks that will be performed during the integrity assessment of the PNL-operated Radioactive Liquid Waste Systems (RLWS) associated with the 324 and 325 Buildings located in the 300 Area of the Hanford Site. It describes the inspections, tests, and analyses required to assess the integrity of the PNL RLWS (tanks, ancillary equipment, and secondary containment) and provides sufficient information for adequate budgeting and control of the assessment program. It also provides necessary information to permit the Independent, Qualified, Registered Professional Engineer (IQRPE) to approve the integrity assessment program.

  15. Integrity assessment plan for PNL 300 area radioactive hazardous waste tank system. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The Pacific Northwest Laboratory (PNL), operated by Battelle Memorial Institute under contract to the U.S. Department of Energy, operates tank systems for the U.S. Department of Energy, Richland Operations Office (DOE-RL), that contain dangerous waste constituents as defined by Washington State Department of Ecology (WDOE) Dangerous Waste Regulations, Washington Administrative Code (WAC) 173-303-040(18). Chapter 173-303-640(2) of the WAC requires the performance of integrity assessments for each existing tank system that treats or stores dangerous waste, except those operating under interim status with compliant secondary containment. This Integrity Assessment Plan (IAP) identifies all tasks that will be performed during the integrity assessment of the PNL-operated Radioactive Liquid Waste Systems (RLWS) associated with the 324 and 325 Buildings located in the 300 Area of the Hanford Site. It describes the inspections, tests, and analyses required to assess the integrity of the PNL RLWS (tanks, ancillary equipment, and secondary containment) and provides sufficient information for adequate budgeting and control of the assessment program. It also provides necessary information to permit the Independent, Qualified, Registered Professional Engineer (IQRPE) to approve the integrity assessment program.

  16. Psychometric Characteristics of a Patient Reported Outcome Measure on Ego-Integrity and Despair among Cancer Patients.

    Directory of Open Access Journals (Sweden)

    Gitta Kleijn

    Full Text Available To evaluate psychometric characteristics of a questionnaire (the Northwestern Ego-integrity Scale (NEIS on ego-integrity (the experience of wholeness and meaning in life, even in spite of negative experiences and despair (the experience of regret about the life one has led, and feelings of sadness, failure and hopelessness among cancer patients.Cancer patients (n = 164 completed patient reported outcome measures on ego-integrity and despair (NEIS, psychological distress, anxiety and depression (Hospital Anxiety and Depression Scale (HADS, and quality of life (EORTC QLQ-C30 (cancer survivors, n = 57 or EORTC QLQ-C15-PAL (advanced cancer patients, n = 107. Confirmatory Factor Analysis was used to assess construct validity. Cronbach's alpha was used to assess internal consistency. Convergent validity was tested based on a priori defined hypotheses: a higher level of ego-integrity was expected to be related to a higher level of quality of life, and lower levels of distress, depression and anxiety; a higher level of despair was expected to be related to a lower level of quality of life, and higher levels of distress, depression and anxiety.The majority of all items (94.5% of the NEIS were completed by patients and single item missing rate was below 2%. The two subscales, labeled as Ego-integrity (5 items and Despair (4 items had acceptable internal consistency (Cronbach's alpha .72 and .61, respectively. The Ego-integrity subscale was not significantly associated with quality of life, distress, anxiety, or depression. The Despair subscale correlated significantly (p <.001 with quality of life (r = -.29, distress (r = .44, anxiety (r = .47 and depression (r = .32.The NEIS has good psychometric characteristics to assess ego-integrity and despair among cancer patients.

  17. Space shuttle auxiliary propulsion system design study. Phase C and E report: Storable propellants, RCS/OMS/APU integration study

    Science.gov (United States)

    Anglim, D. D.; Bruns, A. E.; Perryman, D. C.; Wieland, D. L.

    1972-01-01

    Auxiliary propulsion concepts for application to the space shuttle are compared. Both monopropellant and bipropellant earth storable reaction control systems were evaluated. The fundamental concepts evaluated were: (1) monopropellant and bipropellant systems installed integrally within the vehicle, (2) fuel systems installed modularly in nose and wing tip pods, and (3) fuel systems installed modularly in nose and fuselage pods. Numerous design variations within these three concepts were evaluated. The system design analysis and methods for implementing each of the concepts are reported.

  18. United States Department of Energy Integrated Manufacturing & Processing Predoctoral Fellowships. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Petrochenkov, M.

    2003-03-31

    The objective of the program was threefold: to create a pool of PhDs trained in the integrated approach to manufacturing and processing, to promote academic interest in the field, and to attract talented professionals to this challenging area of engineering. It was anticipated that the program would result in the creation of new manufacturing methods that would contribute to improved energy efficiency, to better utilization of scarce resources, and to less degradation of the environment. Emphasis in the competition was on integrated systems of manufacturing and the integration of product design with manufacturing processes. Research addressed such related areas as aspects of unit operations, tooling and equipment, intelligent sensors, and manufacturing systems as they related to product design.

  19. Building-integrated photovoltaics (BIPV): Analysis and US market potential. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Frantzis, L.; Friedman, D.; Hill, S.; Teagan, P. [Little (Arthur D.), Inc., Cambridge, MA (United States); Strong, S.; Strong, M. [Solar Design Associates, Harvard, MA (United States)

    1995-02-01

    Arthur D. Little, Inc., in conjunction with Solar Design Associates, conducted a study for the US Department of Energy (DOE), Office of Building Technologies (OBT) to determine the market potential for grid-connected, building-integrated photovoltaics (BIPV). This study defines BIPV as two types of applications: (1) where the PV modules are an integral part of the building, often serving as the exterior weathering skin; and (2) the PV modules are mounted on the existing building exterior. Both of these systems are fully integrated with the energy usage of the building and have potential for significant market penetration in the US. Off-grid building applications also offer a near-term market for BIPV, but are not included in the scope of this study.

  20. Design, development, and demonstration of a promising integrated appliance. Phase I: design. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, W. D.; Lawrence, W. T.; Wilson, R. P.

    1977-09-01

    The combination or integration of appliances for the economical recovery of energy which is normally wasted during the operation of heating systems, air conditioners, water heaters, stoves, clothes washers and driers, and refrigerators in homes and commercial buildings was studied. The potential energy savings achievable by using waste heat from one appliance as heat input to another, e.g., water heaters, was estimated, and the economic benefit to the consumer calculated. Six integrated appliance systems, all involving waste heat utilization to augment water heating were identified as economically feasible with a maximum cost payback period of 3.5 y in residential buildings and 5.0 y for commercial buildings. These included heat recovery from furnaces, air conditioners, commercial ranges, heat in water drains in homes, and heat in water drains in commercial buildings. The first three are the most promising. A program to demonstrate the performance of these three integrated appliance systems and to further their commercialization is recommended. (LCL)

  1. 27 CFR 70.482 - Offers in compromise of liabilities (other than forfeiture) under 26 U.S.C.

    Science.gov (United States)

    2010-04-01

    ... 26 U.S.C. (a) In general. The appropriate TTB officer may compromise any civil or criminal liability... liability. (b) Scope of compromise agreement. A compromise agreement may relate to civil or criminal.... However, acceptance of an offer in compromise of a civil liability does not remit a criminal...

  2. Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells.

    Directory of Open Access Journals (Sweden)

    Zsuzsanna A Dunai

    Full Text Available For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner. Necroptosis, a type of programmed necrosis is defined as a death receptor-initiated process under caspase-compromised conditions. The process requires the kinase activity of receptor-interacting protein kinase 1 and 3 (RIPK1 and RIPK3 and mixed lineage kinase domain-like protein (MLKL, as a substrate of RIPK3. The further downstream events remain elusive. We applied known inhibitors to characterize the contributing enzymes in necroptosis and their effect on cell viability and different cellular functions were detected mainly by flow cytometry. Here we report that staurosporine, the classical inducer of intrinsic apoptotic pathway can induce necroptosis under caspase-compromised conditions in U937 cell line. This process could be hampered at least partially by the RIPK1 inhibitor necrotstin-1 and by the heat shock protein 90 kDa inhibitor geldanamycin. Moreover both the staurosporine-triggered and the classical death ligand-induced necroptotic pathway can be effectively arrested by a lysosomal enzyme inhibitor CA-074-OMe and the recently discovered MLKL inhibitor necrosulfonamide. We also confirmed that the enzymatic role of poly(ADP-ribosepolymerase (PARP is dispensable in necroptosis but it contributes to membrane disruption in secondary necrosis. In conclusion, we identified a novel way of necroptosis induction that can facilitate our understanding of the molecular mechanisms of necroptosis. Our results shed light on alternative application of staurosporine, as a possible anticancer therapeutic agent. Furthermore, we showed that the CA-074-OMe has a target in the signaling pathway leading to necroptosis. Finally, we could differentiate necroptotic and secondary necrotic processes based on participation of PARP enzyme.

  3. Immediate versus deferred delivery of the preterm baby with suspected fetal compromise for improving outcomes.

    Science.gov (United States)

    Stock, Sarah J; Bricker, Leanne; Norman, Jane E; West, Helen M

    2016-07-12

    several factors: blinding was not possible due to the nature of the intervention, data for childhood follow-up were incomplete due to attrition, and no adjustment was made in the analysis for the non-independence of babies from multiple pregnancies (39 out of 548 pregnancies). This study only included cases of suspected fetal compromise where there was uncertainty whether immediate delivery was indicated, thus results must be interpreted with caution. Currently there is insufficient evidence on the benefits and harms of immediate delivery compared with deferred delivery in cases of suspected fetal compromise at preterm gestations to make firm recommendations. There is a lack of trials addressing this question, and limitations of the one included trial means that caution must be used in interpreting and generalising the findings. More research is needed to guide clinical practice.Although the included trial is relatively large, it has insufficient power to detect differences in neonatal mortality. It did not report any maternal outcomes other than mode of delivery, or evaluate maternal satisfaction or economic outcomes. The applicability of the findings is limited by several factors: Women with a wide range of obstetric complications and gestational ages were included, and subgroup analysis is currently limited. Advances in Doppler assessment techniques may diagnose severe compromise more accurately and help make decisions about the timing of delivery. The potential benefits of deferring delivery for longer or shorter periods cannot be presumed.Where there is uncertainty whether or not to deliver a preterm fetus with suspected fetal compromise, there seems to be no benefit to immediate delivery. Deferring delivery until test results worsen or increasing gestation favours delivery may improve the outcomes for mother and baby.There is a need for high-quality randomised controlled trials comparing immediate and deferred delivery where there is suspected fetal compromise at

  4. Final Technical Report: Integrated Distribution-Transmission Analysis for Very High Penetration Solar PV

    Energy Technology Data Exchange (ETDEWEB)

    Palmintier, Bryan [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Hale, Elaine [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Hansen, Timothy M. [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Jones, Wesley [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Biagioni, David [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Baker, Kyri [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Wu, Hongyu [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Giraldez, Julieta [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Sorensen, Harry [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Lunacek, Monte [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Merket, Noel [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Jorgenson, Jennie [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States)); Hodge, Bri-Mathias [NREL (National Renewable Energy Laboratory (NREL), Golden, CO (United States))

    2016-01-29

    Transmission and distribution simulations have historically been conducted separately, echoing their division in grid operations and planning while avoiding inherent computational challenges. Today, however, rapid growth in distributed energy resources (DERs)--including distributed generation from solar photovoltaics (DGPV)--requires understanding the unprecedented interactions between distribution and transmission. To capture these interactions, especially for high-penetration DGPV scenarios, this research project developed a first-of-its-kind, high performance computer (HPC) based, integrated transmission-distribution tool, the Integrated Grid Modeling System (IGMS). The tool was then used in initial explorations of system-wide operational interactions of high-penetration DGPV.

  5. NCD Diamond Semiconductor System for Advanced Power Electronics Systems Integration : CRADA report

    Energy Technology Data Exchange (ETDEWEB)

    Sumant, Anirudha [AKHAN Semiconductor, Inc., Hoffman Estates, IL (United States)

    2016-07-22

    The integration of 2D materials such as molybdenum disulphide (MoS2) with diamond (3D) was achieved by forming an heterojunction between these two materials and its electrical performance was studied experimentally. The device charactertics did show good rectifying nature when p-type single crystal diamond was integrated with n-type MoS2. These results are very encouraging indicating possible applications in semiconductor electronics, however further studies are required for a detailed understanding of the transport phenomena at the MoS2/diamond interface.

  6. Ground-Source Integrated Heat Pump for Near-Zero Energy Houses: Technology Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, Richard W [ORNL; Rice, C Keith [ORNL; Baxter, Van D [ORNL; Craddick, William G [ORNL

    2007-09-01

    The energy service needs of a net-zero-energy house (ZEH) include space heating and cooling, water heating, ventilation, dehumidification, and humidification, depending on the requirements of the specific location. These requirements differ in significant ways from those of current housing. For instance, the most recent DOE buildings energy data (DOE/BED 2007) indicate that on average {approx}43% of residential buildings primary energy use is for space heating and cooling, vs. {approx}12% for water heating (about a 3.6:1 ratio). In contrast, for the particular prototype ZEH structures used in the analyses in this report, that ratio ranges from about 0.3:1 to 1.6:1 depending on location. The high-performance envelope of a ZEH results in much lower space heating and cooling loads relative to current housing and also makes the house sufficiently air-tight to require mechanical ventilation for indoor air quality. These envelope characteristics mean that the space conditioning load will be closer in size to the water heating load, which depends on occupant behavior and thus is not expected to drop by any significant amount because of an improved envelope. In some locations such as the Gulf Coast area, additional dehumidification will almost certainly be required during the shoulder and cooling seasons. In locales with heavy space heating needs, supplemental humidification may be needed because of health concerns or may be desired for improved occupant comfort. The U.S. Department of Energy (DOE) has determined that achieving their ZEH goal will require energy service equipment that can meet these needs while using 50% less energy than current equipment. One promising approach to meeting this requirement is through an integrated heat pump (IHP) - a single system based on heat pumping technology. The energy benefits of an IHP stem from the ability to utilize otherwise wasted energy; for example, heat rejected by the space cooling operation can be used for water heating

  7. 32 CFR 310.50 - Lost, stolen, or compromised information.

    Science.gov (United States)

    2010-07-01

    ... reported to: (1) The United States Computer Emergency Readiness Team (US CERT) within one hour of discovering that a breach of personally identifiable information has occurred. Components shall establish...., computer incident, theft, loss of material, etc.) shall continue to be reported in accordance...

  8. Integrated reporting compliance with the Global Reporting Initiative framework : an analysis of the South African financial industry / Eldine van Niekerk

    OpenAIRE

    Van Niekerk, Eldine

    2015-01-01

    In the past, activities of business were motivated exclusively by the desire to maximize their financial returns and the aim of corporate reports was to provide information about the cash flow, financial position and financial performance of an entity. However, over the past decade, increased awareness of developing accounting-style metrics for nonfinancial business influences has led companies from being profit-driven to taking the triple bottom line approach of incorporating ...

  9. Integration and control of wind farms in the Danish electricity system. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Bak-Jensen, B. (ed.); Suwannarat, A.; Chen, Z. (Aalborg Univ.. Dept. of Energy Technology, Aalborg (Denmark)) (and others)

    2009-07-01

    The objective of this project have been to establish and develop a generic model for power balancing studies of the Danish power system as is expected to look like in 2025, with a lot of new wind farms integrated. That is, the objective has been to describe the wind-farms interaction with other power generating units, and the wind farms ability to act as a power plant with regard to the power control and the wind farms ability to maintain the power system stability. Therefore, a dynamic model has been set up, which can reflect the active power balancing in case of wind power fluctuations in the system with a huge wind farm penetration. The set up of the Danish network grid includes the interconnections to Norway, Sweden and Germany and takes into account the power production from the central power plants, the decentralized combined heat and power plants, the power production from the wind turbines on-land as well as off-shore and the load. Also the new Great Belt link is simulated; to see how the usage of this link could optimize the power balance situation. The power production from the different units is controlled by an automatic generation controller, where the different units are controlled by use of a so called participation factor, which determines how the power producing units participate in balancing the power. The participations factors should reflect the market behavior and the unit commitment for the power plants. Therefore, the participation factors are made time dependent, to be able to reflect this market behavior in the future use of the model. Further, the possibility to use balance, delta and gradient control in the wind farms is included together with the possibility to include planned power production from the thermal units. In this report different scenarios have been set up, to show the different possibilities with the model. The primary focus has been to see what could happen if a storm is coming up, and the wind turbines suddenly disconnects

  10. Integrating Archaeological Theory and Predictive Modeling: a Live Report from the Scene

    NARCIS (Netherlands)

    Verhagen, J.W.H.P.; Whitley, T.G.

    2011-01-01

    Archaeological predictive modeling has been used successfully for over20 years as a decision-making tool in cultural resources management. Itsappreciation in academic circles however has been mixed because of its perceivedtheoretical poverty. In this paper, we discuss the issue of integrating curren

  11. Learning and enhanced climate representation in integrated assessment models. Final report, September 1994--May 1997

    Energy Technology Data Exchange (ETDEWEB)

    Kolstad, C.D.

    1997-12-31

    The objective of the project is to enhance capabilities for integrated-assessment modeling in two major areas: learning/R and D/information acquisition and the nexus between climate dynamics and climate impacts. In the first of these areas, the author`s objective is to improve the way in which economic models deal with learning (endogenous and/or exogenous) within an economy. This would obviously include the R and D process, whereby knowledge about climate change (and many other things) is acquired over time and influences regulatory actions. The work in climate dynamics is focused in part on incorporating the regional climate-change results from equilibrium and transient general circulation model (GCM) simulations in the simplified integrated-assessment model. While the work is generic and therefore applicable to any integrated-assessment model, it is done in the context of a standard Ramsey growth model. Thus, the work involves theoretical conceptualization, empirical implementation in an integrated-assessment model, and analysis using that model.

  12. Idaho National Laboratory Integrated Safety Management System FY 2013 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Farren Hunt

    2013-12-01

    Idaho National Laboratory (INL) performed an Annual Effectiveness Review of the Integrated Safety Management System (ISMS), per 48 Code of Federal Regulations (CFR) 970.5223 1, “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and identified target areas for focused improvements and assessments for Fiscal Year (FY) 2014. Results of the FY 2013 annual effectiveness review demonstrate that the INL’s ISMS program is “Effective” and continually improving and shows signs of being significantly strengthened. Although there have been unacceptable serious events in the past, there has also been significant attention, dedication, and resources focused on improvement, lessons learned and future prevention. BEA’s strategy of focusing on these improvements includes extensive action and improvement plans that include PLN 4030, “INL Sustained Operational Improvement Plan, PLN 4058, “MFC Strategic Excellence Plan,” PLN 4141, “ATR Sustained Excellence Plan,” and PLN 4145, “Radiological Control Road to Excellence,” and the development of LWP 20000, “Conduct of Research.” As a result of these action plans, coupled with other assurance activities and metrics, significant improvement in operational performance, organizational competence, management oversight and a reduction in the number of operational events is being realized. In short, the realization of the fifth core function of ISMS (feedback and continuous improvement) and the associated benefits are apparent.

  13. An official American Thoracic Society workshop report: the Integrated Care of The COPD Patient.

    Science.gov (United States)

    Nici, Linda; ZuWallack, Richard

    2012-03-01

    The optimal care of the patient with chronic obstructive pulmonary disease (COPD) requires an individualized, patient-centered approach that recognizes and treats all aspects of the disease, addresses the systemic effects and comorbidities, and integrates medical care among healthcare professionals and across healthcare sectors. In many ways the integration of medical care for COPD is still in its infancy, and its implementation will undoubtedly represent a paradigm shift in our thinking. This article summarizes the proceedings of a workshop, The Integrated Care of the COPD Patient, which was funded by the American Thoracic Society. This workshop included participants who were chosen because of their expertise in the area as well as their firsthand experience with disease management models. Our summary describes the concepts of integrated care and chronic disease management, details specific components of disease management as they may apply to the patient with COPD, and provides several innovative examples of COPD disease management programs originating from different healthcare systems. It became clear from the discussions and review of the literature that more high-quality research in this area is vital. It is our hope that the information presented here provides a "call to arms" in this regard.

  14. The Study of Project Exodus: A School Racial Integration Project in Boston, Massachusetts. Final Report.

    Science.gov (United States)

    Teele, James E.

    This voluntary school integration project uses the open enrollment plan of the Boston School Department in transporting Negro children from predominantly Negro schools in the black district to more racially balanced schools in other parts of Boston. It has involved private financing, intra-city bussing, and the initiative and participation of…

  15. Implementation and Validation of PACS Integrated Peer Review for Discrepancy Recording of Radiology Reporting

    NARCIS (Netherlands)

    Olthof, A. W.; van Ooijen, P. M. A.

    2016-01-01

    The purpose of this work is to demonstrate the possibility of implementation of a PACS-integrated peer review system based on RADPEER T classification providing a step-wise implementation plan utilizing features already present in the standard PACS implementation and without the requirement of addit

  16. Teacher Attitudes toward Muslim Student Integration into Civil Society: A Report from Six European Countries

    Science.gov (United States)

    Sharpes, Donald K.; Schou, Lotte R.

    2014-01-01

    The convergence of Islam and national and cultural identity in Europe, exacerbated by external events like a murder, assassination, riot, embassy bombing or even a satirical cartoon, has the potential for disrupting civic order and eroding movements towards cultural assimilation and national integration. Clearly, fundamentalism in any religion,…

  17. Designing and Building Integrated Digital Library Systems: Guidelines. IFLA Professional Reports, No. 90

    Science.gov (United States)

    Rathje, Bente Dahl; McGrory, Margaret; Pollitt, Carol; Voutilainen, Paivi

    2005-01-01

    The purpose of these Guidelines is to provide libraries for the blind and those who work in them with a broad overview of matters to be considered in planning and implementing an integrated digital library system. The Guidelines are not intended to provide technical solutions. Given the pace of technological change, solutions can only be developed…

  18. Evaluating an Integrated Approach to the Management of Cerebral Palsy. Volume I of IV. Final Report.

    Science.gov (United States)

    Heal, Laird W.

    The integrated Management of Cerebral Palsy (IMCP) project evaluated the effectiveness of a program of conductive education, which was said to involve training motorically disabled children in small, motivating groups of similarly handicapped peers to actively and voluntarily pursue those movements that are both incompatible with reflexes and…

  19. Travel choice models that generate preferences for compromise alternatives : An empirical comparison

    NARCIS (Netherlands)

    Chorus, C.G.; Bierlaire, M.

    2013-01-01

    Compromise alternatives have an intermediate performance on each or most attributes rather than having a poor performance on some attributes and a strong performance on others. The relative popularity of compromise alternatives among decision-makers has been convincingly established in a wide range

  20. Cross-cultural compromises, multiculturalism and the actuality of unzipped Hofstede

    NARCIS (Netherlands)

    S.J. Magala (Slawomir)

    2004-01-01

    textabstractCultural background of identities calls for upholding of values, but realities of multicultural interactions require cross-cultural compromises. Compromises begin already with the introduction of the term multiculturalism, which served both as a platform for cross-cultural urban policies

  1. Compromised motor control in children with DCD: A deficit in the internal model - a systematic review

    NARCIS (Netherlands)

    Adams, I.L.J.; Lust, J.M.; Wilson, P.H.; Steenbergen, B.

    2014-01-01

    A viable hypothesis to explain the compromised motor ability of children with Developmental Coordination Disorder (DCD) suggests a fundamental deficit in their ability to utilize internal models for motor control. Dysfunction in this mode of control is thought to compromise their motor learning

  2. 10 CFR 15.41 - When a claim may be compromised.

    Science.gov (United States)

    2010-01-01

    ... it has not been referred to DOJ for litigation. (b) Unless otherwise provided by law, when the... with the DOJ. The NRC will evaluate the compromise offer, using the factors set forth in this part. If an offer to compromise any debt in excess of $100,000 is acceptable to the NRC, the NRC shall...

  3. 13 CFR 108.1710 - SBA authority to collect or compromise its claims.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false SBA authority to collect or compromise its claims. 108.1710 Section 108.1710 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION...) Miscellaneous § 108.1710 SBA authority to collect or compromise its claims. SBA may, upon such conditions...

  4. Compromised motor control in children with DCD: A deficit in the internal model - a systematic review

    NARCIS (Netherlands)

    Adams, I.L.J.; Lust, J.M.; Wilson, P.H.; Steenbergen, B.

    2014-01-01

    A viable hypothesis to explain the compromised motor ability of children with Developmental Coordination Disorder (DCD) suggests a fundamental deficit in their ability to utilize internal models for motor control. Dysfunction in this mode of control is thought to compromise their motor learning capa

  5. Near-infrared spectroscopy for detection of vascular compromise in paediatric supracondylar fractures.

    Science.gov (United States)

    Skowno, Justin J; Quick, Tom J; Carpenter, Eleanor C; De Lima, Jonathan; Gibbons, Paul J; Little, David G

    2014-03-01

    Children suffering supracondylar fractures of the humerus are at risk of vascular compromise, which is currently assessed clinically, although other modalities such as angiography, pulse oximetry, Doppler ultrasound and magnetic resonance angiography have been used. We sought to ascertain whether tissue haemoglobin oxygenation (StO2) measurement could distinguish between patients with and without clinical vascular compromise following supracondylar fractures of the humerus. We prospectively observed StO2 using near-infrared spectroscopy in 29 paediatric patients with supracondylar fractures requiring operative manipulation. The injured and uninjured volar forearm compartments were monitored immediately before and after fracture reduction. The relationship between StO2 in the injured and uninjured limb, and the presence of pre-operative vascular compromise was assessed. Seven out of 29 children presented with vascular compromise. Patients with clinical vascular compromise had significantly lower pre-reduction StO2 (63.5% ± 15%, mean ± standard deviation), compared to those without compromise (80.9% ± 10%). StO2 normalized following surgery in all children with vascular compromise. These improvements in muscle StO2 were associated, in all patients, with the clinical return of pulses and resolution of neurological symptoms if present. StO2 monitoring can identify patients with clinical vascular compromise, can identify the return of adequate perfusion following operative correction of supracondylar fractures, and may be a useful adjunct to clinical assessment.

  6. 7 CFR 1956.68 - Compromise or adjustment without debtor's signature.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Compromise or adjustment without debtor's signature... Loan Programs and Multi-Family Housing § 1956.68 Compromise or adjustment without debtor's signature... made to obtain the debtor's signature and the date(s) of such effort. (c) The specific reasons why...

  7. MoH+: A Global, Integrated, and Automated View of Official Outbreak Reporting

    OpenAIRE

    Bahk, Chi; Scales, David; Mekaru, Sumiko; Brownstein, John S.; Freifeld, Clark

    2013-01-01

    Objective: To introduce MoH+, HealthMap’s (HM) real-time feed of official government sources, and demonstrate its utility in comparing the timeliness of outbreak reporting between official and unofficial sources. Introduction: Previous studies have documented significant lags in official reporting of outbreaks compared to unofficial reporting (1,2). MoH+ provides an additional tool to analyze this issue, with the unique advantage of actively gathering a wide range of streamlined official comm...

  8. Towards an Integrated Approach to Perception and Action: Conference Report and Future Directions

    Directory of Open Access Journals (Sweden)

    Goren eGordon

    2011-04-01

    Full Text Available This article was motivated by the conference entitled ‘Perception & Action – An Interdisciplinary Approach to Cognitive Systems Theory’, which took place September 14-16, 2010 at the Santa Fe Institute, NM, U.S.A. The goal of the conference was to bring together an interdisciplinary group of neuroscientists, roboticists and theorists to discuss the extent and implications of action-perception integration in the brain. The motivation for the conference was the realization that it is a widespread approach in biological, theoretical and computational neuroscience to investigate sensory and motor function of the brain in isolation from one another, while at the same time, it is generally appreciated that sensory and motor processing cannot be fully separated. Our article summarizes the key findings of the conference, provides a hypothetical model that integrates the major themes and concepts presented at the conference, and concludes with a perspective on future challenges in the field.

  9. Report of the Integrative Molecular Cancer Epidemiology International Symposium, Lyon, France.

    Science.gov (United States)

    Raimondi, S

    2008-01-01

    An International Symposium on Integrative Molecular Cancer Epidemiology took place in Lyon, France, on 3-5 July 2008. The Symposium focused on aetiological and mechanistic aspects of molecular and genetic cancer epidemiology research and was divided into the following three sections: Molecular epidemiology-application of novel molecular markers to cancer epidemiology.Genomic epidemiology in the era of whole genome scan.INTEGRATIVE MOLECULAR EPIDEMIOLOGY: visions for the future.Participants included epidemiologists, geneticists, biochemical and molecular biologists, pharmacologists, pathologists and all researchers interested in this field. The Symposium provided a complete and clear overview of the present and future programmes in molecular cancer epidemiology. It also served to encourage international scientific collaboration between investigators working in this specific research field, and to stimulate transdisciplinary research with experts of other research areas. Highlights of each of the scientific presentations are summarized below.

  10. Integrated Biorefinery Project: Cooperative Research and Development Final Report, CRADA Number CRD-10-390

    Energy Technology Data Exchange (ETDEWEB)

    Chapeaux, A.; Schell, D.

    2013-06-01

    The Amyris-NREL CRADA is a sub-project of Amyris?s DOE-funded pilot-scale Integrated Biorefinery (IBR). The primary product of the Amyris IBR is Amyris Renewable Diesel. Secondary products will include lubricants, polymers and other petro-chemical substitutes. Amyris and its project partners will execute on a rapid project to integrate and leverage their collective expertise to enable the conversion of high-impact biomass feedstocks to these advanced, infrastructure-compatible products. The scope of the Amyris-NREL CRADA includes the laboratory development and pilot scale-up of bagasse pretreatment and enzymatic saccharification conditions by NREL for subsequent conversion of lignocellulosic sugar streams to Amyris Diesel and chemical products by Amyris. The CRADA scope also includes a techno-economic analysis of the overall production process of Amyris products from high-impact biomass feedstocks.

  11. Advanced Communication and Control for Distributed Energy Resource Integration: Phase 2 Scientific Report

    Energy Technology Data Exchange (ETDEWEB)

    BPL Global

    2008-09-30

    The objective of this research project is to demonstrate sensing, communication, information and control technologies to achieve a seamless integration of multivendor distributed energy resource (DER) units at aggregation levels that meet individual user requirements for facility operations (residential, commercial, industrial, manufacturing, etc.) and further serve as resource options for electric and natural gas utilities. The fully demonstrated DER aggregation system with embodiment of communication and control technologies will lead to real-time, interactive, customer-managed service networks to achieve greater customer value. Work on this Advanced Communication and Control Project (ACCP) consists of a two-phase approach for an integrated demonstration of communication and control technologies to achieve a seamless integration of DER units to reach progressive levels of aggregated power output. Phase I involved design and proof-of-design, and Phase II involves real-world demonstration of the Phase I design architecture. The scope of work for Phase II of this ACCP involves demonstrating the Phase I design architecture in large scale real-world settings while integrating with the operations of one or more electricity supplier feeder lines. The communication and control architectures for integrated demonstration shall encompass combinations of software and hardware components, including: sensors, data acquisition and communication systems, remote monitoring systems, metering (interval revenue, real-time), local and wide area networks, Web-based systems, smart controls, energy management/information systems with control and automation of building energy loads, and demand-response management with integration of real-time market pricing. For Phase II, BPL Global shall demonstrate the Phase I design for integrating and controlling the operation of more than 10 DER units, dispersed at various locations in one or more Independent System Operator (ISO) Control Areas, at

  12. Esthetic integration between ceramic veneers and composite restorations: a case report.

    Science.gov (United States)

    Farronato, Davide; Mangano, Francesco; Pieroni, Stefano; Lo Giudice, Giuseppe; Briguglio, Roberto; Briguglio, Francesco

    2012-07-01

    The tooth structure preservation is the best way to postpone more invasive therapies. Especially in young patients more conservative techniques should be applied. Bonded porcelain veneers and even more the direct composite restorations, are the two therapeutic procedures that require the fewer sacrifice of dental tissue, finalized to the optimal recovery of aesthetic and functional outcome.Although the two techniques require different methods and materials, is possible to achieve a correct integration of both the methods by some technical and procedural measures. In the presented case is planned a rehabilitation of the four upper incisors by ceramic veneers and direct composite restorations.Care is taken for the surface treatment of ceramic restorations, with the objective of achieving integration, not only between natural teeth and restorations, but also between the different materials in use.The purpose of this article is to show how a proper design of the treatment plan leads to obtain predictable results with both direct and indirect techniques.

  13. In Vitro Assessment of Gamete Integrity

    Science.gov (United States)

    Drug and xenobiotics can compromise reproductive function by impairing gamete physiology and thereby blocking fertilization, or by damaging gamete DNA or chromatin and thereby causing pregnancy failure or birth defects. tandard measures of gamete integrity, such as morphology, mo...

  14. Report: Congressionally Requested Information on EPA Utilization of Integrated Risk Information System

    Science.gov (United States)

    Report #13-P-0127, January 31, 2013. 85 percent of the EPA survey respondents reported that they have used IRIS as their primary source for cancer values and 81 percent have used IRIS as their primary source for non-cancer values.

  15. 78 FR 57624 - Availability of a Draft Integrated Feasibility Report (Feasibility Study/Environmental Impact...

    Science.gov (United States)

    2013-09-19

    ... Study/Environmental Impact Statement/Environmental Impact Report), Los Angeles River Ecosystem Restoration Study, City of Los Angeles, Los Angeles County, CA AGENCY: Department of the Army, U.S. Army Corps... Feasibility Report (IFR), which includes a Draft Feasibility Study (FS) and Environmental Impact...

  16. Adult Education and (Dis)integration Processes in Yugoslavia. Uppsala Reports on Education 22.

    Science.gov (United States)

    Bron, Michal, Jr.

    This report is a synopsis of a study that dealt with the dominant problem in Yugoslavian society, namely the phenomenon of social and economic crisis, and with the role of adult education within the disintegration processes. In addition to an introduction, the report consists of five sections concerning the following issues: (1) the country in a…

  17. Information Integration for Concurrent Engineering (IICE) IDEF3 Process Description Capture Method Report

    Science.gov (United States)

    1995-09-01

    reference manual. report logic-92-1. Logic Group, Stanford University, CA. Gödel, K. (1931). Über Formal Unentscheidbare Sätze der Principia ... Mathematica und Verwandter Systeme, I. Monatshefte Für Mathematik und Physik 38, 173-198. IDEF Users Group. (1990). IDEF: framework, draft report

  18. Engineered Barrier System - Mechanical Integrity of KBS-3 Spent Fuel Canisters. Report from a Workshop. Synthesis and extended abstracts

    Energy Technology Data Exchange (ETDEWEB)

    2007-09-15

    SKI is preparing to review the license applications being developed by the Swedish Nuclear Fuel and Waste Management Company (SKB) for a final repository for the geological disposal of spent nuclear fuel in the year 2009. As part of its preparation, SKI is conducting a series of technical workshops on key aspects of the Engineered Barrier System (EBS). The workshop reported here mainly dealt with the mechanical integrity of KBS-3 spent fuel canisters. This included assessment and review of various loading conditions, structural integrity models and mechanical properties of the copper shell and the cast iron insert. Degradation mechanisms such as stress corrosion cracking and brittle creep fracture were also briefly addressed. Previous workshops have addressed the overall concept for long-term integrity of the EBS, the manufacturing, testing and QA of the EBS, the performance confirmation for the EBS, long-term stability of the buffer and the backfill, corrosion properties of copper canisters and the spent fuel dissolution and source term modelling. The goal of ongoing review work in connection of the workshop series is to achieve a comprehensive overview of all aspects of SKB's EBS and spent fuel work prior to the handling of the forthcoming license application. This report aims to summarise the issues discussed at the workshop and to extract the essential viewpoints that have been expressed. The report is not a comprehensive record of all the discussions at the workshop, and individual statements made by workshop participants should be regarded as personal opinions rather than SKI viewpoints. Results from the EBS workshops series will be used as one important basis in future review work. This reports includes in addition to the workshop synthesis, questions to SKB identified prior to the workshop, and extended abstracts for introductory presentations

  19. The Role of Integrated Indicators in Exhibiting Business Contribution to Sustainable Development: a Survey of Sustainability Reporting Initiatives

    Directory of Open Access Journals (Sweden)

    Fernando Azcárate

    2011-12-01

    Full Text Available Pag. THE ROLE OF INTEGRATED INDICATORS IN EXHIBITING BUSINESS CONTRIBUTION TO SUSTAINABLE DEVELOPMENT: A SURVEY OF SUSTAINABILITY REPORTING INITIATIVESEL PAPEL DE LOS INDICADORES INTEGRADOS EN LA CONTRIBUCIÓN EMPRESARIAL AL DESARROLLO SOSTENIBLE: UN ESTUDIO DE LAS INICIATIVAS PARA EL REPORTING DE SOSTENIBILIDADEl papel de los indicadores integrados en la contribución empresarial al desarrollo sostenible: un estudio de las iniciativas para el reporting de sostenibilidadThis paper aims to analyse the role of integrated indicators included in sustainability reporting initiatives in exhibiting business contribution to Sustainable Development.Content analysis of five core initiatives has been carried out to identify strong or weak sustainability arguments within the whole set of indicators. According to the findings, the analyzed initiatives raise a collection of integrated indicators that suggest managerial capture of the concept of Sustainable Development.El presente trabajo aborda el estudio de los indicadores integrados como elemento central para conseguir que las memorias de sostenibilidad cumplan el objetivo de mostrar la contribución que una organización realiza a la consecución del Desarrollo Sostenible. Para ello se ha realizado un análisis de contenido de cinco de las principales iniciativas internacionales que las empresas pueden utilizar como guía para elaborar sus memorias de sostenibilidad con el objetivo de identificar los indicadores integrados que proponen y evidenciar cuál es la visión de la sostenibilidad que en ellos subyace. Los resultados muestran que las iniciativas analizadas plantean un conjunto de indicadores integrados que favorece que las organizaciones puedan capturar el concepto de Desarrollo Sostenible.

  20. Planned early delivery versus expectant management of the term suspected compromised baby for improving outcomes.

    Science.gov (United States)

    Bond, Diana M; Gordon, Adrienne; Hyett, Jon; de Vries, Bradley; Carberry, Angela E; Morris, Jonathan

    2015-11-24

    Fetal compromise in the term pregnancy is suspected when the following clinical indicators are present: intrauterine growth restriction (IUGR), decreased fetal movement (DFM), or when investigations such as cardiotocography (CTG) and ultrasound reveal results inconsistent with standard measurements. Pathological results would necessitate the need for immediate delivery, but the management for 'suspicious' results remains unclear and varies widely across clinical centres. There is clinical uncertainty as to how to best manage women presenting with a suspected term compromised baby in an otherwise healthy pregnancy. To assess, using the best available evidence, the effects of immediate delivery versus expectant management of the term suspected compromised baby on neonatal, maternal and long-term outcomes. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 May 2015) and reference lists of retrieved studies. Randomised or quasi-randomised controlled trials comparing expectant management versus planned early delivery for women with a suspected compromised fetus from 37 weeks' gestation or more. Two review authors independently assessed trials for inclusion and assessed trial quality. Two review authors independently extracted data. Data were checked for accuracy. We assessed the quality of the evidence using the GRADE approach. Of the 20 reports identified by the search strategy, we included three trials (546 participants: 269 to early delivery and 277 to expectant management), which met our inclusion criteria. Two of the trials compared outcomes in 492 pregnancies with IUGR of the fetus, and one in 54 pregnancies with oligohydramnios. All three trials were of reasonable quality and at low risk of bias. The level of evidence was graded moderate, low or very low, downgrading mostly for imprecision and for some indirectness. Overall, there was no difference in the primary neonatal outcomes of perinatal mortality (no deaths in either group, one

  1. Osseocutaneous integration of an intraosseous transcutaneous amputation prosthesis implant used for reconstruction of a transhumeral amputee: case report.

    Science.gov (United States)

    Kang, Norbert V; Pendegrass, Catherine; Marks, Linda; Blunn, Gordon

    2010-07-01

    Exoprosthetic replacement with an artificial limb is the main option for reconstruction after traumatic amputation of an upper limb. Direct skeletal attachment using an osseointegrated implant improves the ease of fixation of the exoprosthesis to the amputation stump. We now report the use of an intraosseous transcutaneous amputation prosthesis that is designed to achieve osseocutaneous integration. Osseocutaneous integration differs from osseointegration because the aim is to create a stable interface among the implant, the bone, and the soft tissues. This reduces the risk of soft tissue infection and troublesome discharge, which are problems encountered with current osseointegrated implants that focus largely on the bone-implant interface. We describe our experience with an intraosseous transcutaneous amputation prosthesis in a case of transhumeral amputation with 2 years of follow-up.

  2. Magnetic nanoparticles-doped silica layer reported on ion-exchanged glass waveguide: towards integrated magneto-optical devices

    Science.gov (United States)

    Amata, Hadi; Royer, François; Choueikani, Fadi; Jamon, Damien; Broquin, Jean-Emmanuel; Plenet, Jean Claude; Rousseau, Jean Jaques

    2010-05-01

    In the framework of optical telecommunication systems, many functions are integrated on the same substrate. Nevertheless, one of the most important, such as isolation, is achieved using discrete components. It is based on magnetic materials which are always difficult to integrate with classical technologies. This is due to the annealing temperature of magnetic materials. In this paper we present another way for the realisation of such components. We use a dip coating process to report a magnetic nanoparticles doped silica layer on ion-exchanged glass waveguide. The advantages of this method is discussed and we demonstrate its compatibility with ion-exchanged technology. By varying the refractive index of the layer, we can adjust the interaction between the waveguide and the magneto-optical layer.

  3. 26 CFR 601.203 - Offers in compromise.

    Science.gov (United States)

    2010-04-01

    ... penalty and the District Counsel concurs in the acceptance of the offer, or (iv) Recommend to the Regional Commissioner the acceptance of the offer if it involves a civil liability of $100,000 or over. (2)(i) If the... acceptance or rejection of the offer together with the examining officer's report of the investigation....

  4. 14 CFR 1261.414 - Compromise of claims.

    Science.gov (United States)

    2010-01-01

    ... the Claims Collection Litigation Report. See § 1261.417(e) or 4 CFR 105.2(b). Claims for which the... potential income; (3) Inheritance prospects; (4) The possibility that assets have been concealed or... which collateral or other property will bring at forced sale may properly be considered in...

  5. Phase 2 Report: Oahu Wind Integration and Transmission Study (OWITS); Hawaiian Islands Transmission Interconnection Project

    Energy Technology Data Exchange (ETDEWEB)

    Woodford, D.

    2011-02-01

    This report provides an independent review including an initial evaluation of the technical configuration and capital costs of establishing an undersea cable system and examining impacts to the existing electric transmission systems as a result of interconnecting the islands

  6. Data Summary Report for Savannah River Integrator Operable Unit Fish Tissue

    Energy Technology Data Exchange (ETDEWEB)

    Craig, B.

    2001-02-13

    This report presents the results of the verification and validation of the analytical data for the Savannah River Fish (SRF) investigation. The data were validated to determine if the records conform to the technical criteria associated with definitive data.

  7. Hawaii Utility Integration Initiatives to Enable Wind (Wind HUI) Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Dora Nakafuji; Lisa Dangelmaier; Chris Reynolds

    2012-07-15

    To advance the state and nation toward clean energy, Hawaii is pursuing an aggressive Renewable Portfolio Standard (RPS), 40% renewable generation and 30% energy efficiency and transportation initiatives by 2030. Additionally, with support from federal, state and industry leadership, the Hawaii Clean Energy Initiative (HCEI) is focused on reducing Hawaii's carbon footprint and global warming impacts. To keep pace with the policy momentum and changing industry technologies, the Hawaiian Electric Companies are proactively pursuing a number of potential system upgrade initiatives to better manage variable resources like wind, solar and demand-side and distributed generation alternatives (i.e. DSM, DG). As variable technologies will continue to play a significant role in powering the future grid, practical strategies for utility integration are needed. Hawaiian utilities are already contending with some of the highest penetrations of renewables in the nation in both large-scale and distributed technologies. With island grids supporting a diverse renewable generation portfolio at penetration levels surpassing 40%, the Hawaiian utilities experiences can offer unique perspective on practical integration strategies. Efforts pursued in this industry and federal collaborative project tackled challenging issues facing the electric power industry around the world. Based on interactions with a number of western utilities and building on decades of national and international renewable integration experiences, three priority initiatives were targeted by Hawaiian utilities to accelerate integration and management of variable renewables for the islands. The three initiatives included: Initiative 1: Enabling reliable, real-time wind forecasting for operations by improving short-term wind forecasting and ramp event modeling capabilities with local site, field monitoring; Initiative 2: Improving operators situational awareness to variable resources via real-time grid condition

  8. An investigation of the integrated reporting disclosure practices of the top 40 listed South African companies

    OpenAIRE

    Marchbank, Melanie Shirley

    2016-01-01

    Abstract: Over the last two decades, significant events have led to some of the largest business failures ever seen in the financial sector, such as Enron and WorldCom (Constancio 2011; Deegan 2009; Luez & Wysocki 2008). These business failures have led to financial reporting no longer being viewed from a financial perspective alone, but also from a non-financial perspective. King Code III had a significant impact on the reporting requirements of the Johannesburg Securities Exchange (JSE) and...

  9. Integrated system for coal-methanol liquefaction and slurry pipeline transportation. Final report. [In slurry transport

    Energy Technology Data Exchange (ETDEWEB)

    Banks, W.F.; Davidson, J.K.; Horton, J.H.; Summers, C.W.

    1980-03-31

    The engineering economics of an integrated coal-to-methanol conversion system and coal-in-methanol transportation system are examined, under the circumstances of the western coalfields, i.e., long distances from major markets and scarcity of water in the vicinity of the mines. The transportation economics are attractive, indicating tariffs of approximately 40 cents per million Btu per thousand miles for the coal-methanol pipeline vs 60 cents via coal-water pipelines and upwards of a dollar via rail. Energy consumption is also less in the coal-methanol pipeline than in the coal-water pipeline, and about equal to rail. It is also concluded that, by a proper marriage of the synthetic fuel (methanolization) plant to the slurrification plant, most, and in some cases all, of the water required by the synthetic fuel process can be supplied by the natural moisture of the coal itself. Thus, the only technology which presently exists and by which synthetic fuel from western coal can displace petroleum in the automotive fuel market is the integrated methanol conversion and tranportation system. The key element is the ability of the methanol slurry pipeline to accept and to deliver dry (1 to 5% moisture) coal, allowing the natural coal moisture to be used as synthesis feedstock in satisfaction of the large water requirement of any synthetic fuel plant. By virtue of these unique properties, this integrated system is seen as the only means in the foreseeable future whereby western coal can be converted to synthetic fuel and moved to distant markets.

  10. Solid waste integrated cost analysis model: 1991 project year report. Part 2

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    The purpose of the City of Houston`s 1991 Solid Waste Integrated Cost Analysis Model (SWICAM) project was to continue the development of a computerized cost analysis model. This model is to provide solid waste managers with tool to evaluate the dollar cost of real or hypothetical solid waste management choices. Those choices have become complicated by the implementation of Subtitle D of the Resources Conservation and Recovery Act (RCRA) and the EPA`s Integrated Approach to managing municipal solid waste;. that is, minimize generation, maximize recycling, reduce volume (incinerate), and then bury (landfill) only the remainder. Implementation of an integrated solid waste management system involving all or some of the options of recycling, waste to energy, composting, and landfilling is extremely complicated. Factors such as hauling distances, markets, and prices for recyclable, costs and benefits of transfer stations, and material recovery facilities must all be considered. A jurisdiction must determine the cost impacts of implementing a number of various possibilities for managing, handling, processing, and disposing of waste. SWICAM employs a single Lotus 123 spreadsheet to enable a jurisdiction to predict or assess the costs of its waste management system. It allows the user to select his own process flow for waste material and to manipulate the model to include as few or as many options as he or she chooses. The model will calculate the estimated cost for those choices selected. The user can then change the model to include or exclude waste stream components, until the mix of choices suits the user. Graphs can be produced as a visual communication aid in presenting the results of the cost analysis. SWICAM also allows future cost projections to be made.

  11. SRNL report for the tank waste disposition integrated flowsheet: Corrosion testing

    Energy Technology Data Exchange (ETDEWEB)

    Wyrwas, R. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-09-30

    A series of cyclic potentiodynamic polarization (CPP) tests were performed in support of the Tank Waste Disposition Integrated Flowsheet (TWDIF). The focus of the testing was to assess the effectiveness of the SRNL model for predicting the amount of nitrite inhibitor needed to prevent pitting induced by increasing halide concentrations. The testing conditions were selected to simulate the dilute process stream that is proposed to be returned to tank farms from treating the off-gas from the low activity waste melter in the Waste Treatment and Immobilization Plant.

  12. ICLIPS - integrated assessment of climate protection strategies. Final report; ICLIPS - Integrierte Abschaetzung von Klimaschutzstrategien. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Toth, F.L.; Bruckner, T.; Fuessel, H.M.

    2000-12-01

    The ICLIPs project is connected to the development of integrated climate impact research in Germany. It is concerned not only with a single dimension of possible impacts of climate change, but it also investigates these impacts in the context of adaptation options and mitigation possibilities. The Tolerable Windows Approach (TWA) permits the explicit consideration of both ecological and economic requirements in identifying tolerable climate protection strategies. This way it fulfills the central objective of science policy related to the complex issue of 'Sustainable Growth'. In the project period, the ICLIPS model, a detailed integrated model of global climate change ('Integrated Assessment Model', IAM) was developed in the framework of a successful international cooperation. As a result, climate impact research in Germany succeeded to catch up with the international forefront in a research field that is very important for practical policy advice, and even managed to take a leading role in some important sub-fields. The ICLIPS model contains a series of innovative features that clearly distinguish this model from other intertemporal optimization models. The features worth mentioning here include: a numerically highly efficient climate model that covers all relevant greenhouse gases; a series of Climate Impact Response Functions that depict climate-relevant changes in natural vegetation systems, agricultural yields, and water availability; and finally a model of long-term economic development that explicitly considers the cost-reducing effects of technological learning. (orig.) [German] Das ICLIPS-Projekt bezieht sich auf die Weiterentwicklung der integrierten Klimafolgenforschung in Deutschland, die sich nicht nur eindimensional mit moeglichen Auswirkungen von Klimaveraenderungen beschaeftigt, sondern diese zusammen mit Anpassungsoptionen und Vermeidungsmoeglichkeiten untersucht. Der Fensteransatz, der bei der Identifizierung von tolerierbaren

  13. Reporter Proteins in Whole-Cell Optical Bioreporter Detection Systems, Biosensor Integrations, and Biosensing Applications

    Science.gov (United States)

    Close, Dan M.; Ripp, Steven; Sayler, Gary S.

    2009-01-01

    Whole-cell, genetically modified bioreporters are designed to emit detectable signals in response to a target analyte or related group of analytes. When integrated with a transducer capable of measuring those signals, a biosensor results that acts as a self-contained analytical system useful in basic and applied environmental, medical, pharmacological, and agricultural sciences. Historically, these devices have focused on signaling proteins such as green fluorescent protein, aequorin, firefly luciferase, and/or bacterial luciferase. The biochemistry and genetic development of these sensor systems as well as the advantages, challenges, and common applications of each one will be discussed. PMID:22291559

  14. Reporter Proteins in Whole-Cell Optical Bioreporter Detection Systems, Biosensor Integrations, and Biosensing Applications

    Directory of Open Access Journals (Sweden)

    Gary S. Sayler

    2009-11-01

    Full Text Available Whole-cell, genetically modified bioreporters are designed to emit detectable signals in response to a target analyte or related group of analytes. When integrated with a transducer capable of measuring those signals, a biosensor results that acts as a self-contained analytical system useful in basic and applied environmental, medical, pharmacological, and agricultural sciences. Historically, these devices have focused on signaling proteins such as green fluorescent protein, aequorin, firefly luciferase, and/or bacterial luciferase. The biochemistry and genetic development of these sensor systems as well as the advantages, challenges, and common applications of each one will be discussed.

  15. Final Scientific/Technical Report for "Nanite" for Better Well-Bore Integrity and Zonal Isolation

    Energy Technology Data Exchange (ETDEWEB)

    Veedu, Vinod [Oceanit Laboratories, Inc., Honolulu, HI (United States); Hadmack, Michael [Oceanit Laboratories, Inc., Honolulu, HI (United States); Pollock, Jacob [Oceanit Laboratories, Inc., Honolulu, HI (United States); Pernambuco-Wise, Paul [Oceanit Laboratories, Inc., Honolulu, HI (United States); Ah Yo, Derek [Oceanit Laboratories, Inc., Honolulu, HI (United States)

    2017-05-30

    Nanite™ is a cementitious material that contains a proprietary formulation of functionalized nanomaterial additive to transform conventional cement into a smart material responsive to pressure (or stress), temperature, and any intrinsic changes in composition. This project has identified optimal sensing modalities of smart well cement and demonstrated how real-time sensing of Nanite™ can improve long-term wellbore integrity and zonal isolation in shale gas and applicable oil and gas operations. Oceanit has explored Nanite’s electrical sensing properties in depth and has advanced the technology from laboratory proof-of-concept to sub-scale testing in preparation for field trials.

  16. Final Technical Report - Integrated Hydrogeophysical and Hydrogeologic Driven Parameter Upscaling for Dual-Domain Transport Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Shafer, John M

    2012-11-05

    The three major components of this research were: 1. Application of minimally invasive, cost effective hydrogeophysical techniques (surface and borehole), to generate fine scale (~1m or less) 3D estimates of subsurface heterogeneity. Heterogeneity is defined as spatial variability in hydraulic conductivity and/or hydrolithologic zones. 2. Integration of the fine scale characterization of hydrogeologic parameters with the hydrogeologic facies to upscale the finer scale assessment of heterogeneity to field scale. 3. Determination of the relationship between dual-domain parameters and practical characterization data.

  17. Performance-Based Technology Selection Filter description report. INEL Buried Waste Integrated Demonstration System Analysis project

    Energy Technology Data Exchange (ETDEWEB)

    O`Brien, M.C.; Morrison, J.L.; Morneau, R.A.; Rudin, M.J.; Richardson, J.G.

    1992-05-01

    A formal methodology has been developed for identifying technology gaps and assessing innovative or postulated technologies for inclusion in proposed Buried Waste Integrated Demonstration (BWID) remediation systems. Called the Performance-Based Technology Selection Filter, the methodology provides a formalized selection process where technologies and systems are rated and assessments made based on performance measures, and regulatory and technical requirements. The results are auditable, and can be validated with field data. This analysis methodology will be applied to the remedial action of transuranic contaminated waste pits and trenches buried at the Idaho National Engineering Laboratory (INEL).

  18. Integration of thermal photovoltaic hybrid sensors to the building. Final report july 2004. Integrated research project 6.2; Integration de capteurs hybrides photovoltaiques thermiques au bati. Rapport final juillet 2004. Projet de recherche integre 6.2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The electricity and the heat are two complementary energies necessary for the accommodation. A thermal solar installation needs the electric power for the coolant fluid flow. This research project concerns the optimization of integrated solutions to the building, providing simultaneously these two energies. This document presents the proposed researches programs: analysis of the socio-economic aspects, the physical phenomena knowledge, simulation of the behavior, experimentation, hybrid components integration, simulation of the photovoltaic modules operating and thermal simulation of an electric converter. (A.L.B.)

  19. Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk.

    Science.gov (United States)

    Daneshian, Mardas; Kamp, Hennicke; Hengstler, Jan; Leist, Marcel; van de Water, Bob

    2016-05-01

    The integrated European project, EU-ToxRisk, proudly sees itself as "flagship" exploring new alternative-to-animal approaches to chemical safety evaluation. It promotes mechanism-based toxicity testing and risk assessment according to the principles laid down for toxicology for the twenty-first century. The project was officially launched in January 2016 with a kickoff meeting in Egmond aan Zee, the Netherlands. Over 100 scientists representing academia and industry as well as regulatory authorities attended the inaugural meeting. The project will integrate advances in in vitro and in silico toxicology, read-across methods, and adverse outcome pathways. EU-ToxRisk will continue to make use of the case study strategy deployed in SEURAT-1, a FP7 initiative ended in December 2015. Even though the development of new non-animal methods is one target of EU-ToxRisk, the project puts special emphasis on their acceptance and implementation in regulatory contexts. This €30 million Horizon 2020 project involves 38 European partners and one from the USA. EU-ToxRisk aims at the "development of a new way of risk assessment."

  20. Advanced Communication and Control for Distributed Energy Resource Integration: Phase 2 Scientific Report

    Energy Technology Data Exchange (ETDEWEB)

    BPL Global

    2008-09-30

    The objective of this research project is to demonstrate sensing, communication, information and control technologies to achieve a seamless integration of multivendor distributed energy resource (DER) units at aggregation levels that meet individual user requirements for facility operations (residential, commercial, industrial, manufacturing, etc.) and further serve as resource options for electric and natural gas utilities. The fully demonstrated DER aggregation system with embodiment of communication and control technologies will lead to real-time, interactive, customer-managed service networks to achieve greater customer value. Work on this Advanced Communication and Control Project (ACCP) consists of a two-phase approach for an integrated demonstration of communication and control technologies to achieve a seamless integration of DER units to reach progressive levels of aggregated power output. Phase I involved design and proof-of-design, and Phase II involves real-world demonstration of the Phase I design architecture. The scope of work for Phase II of this ACCP involves demonstrating the Phase I design architecture in large scale real-world settings while integrating with the operations of one or more electricity supplier feeder lines. The communication and control architectures for integrated demonstration shall encompass combinations of software and hardware components, including: sensors, data acquisition and communication systems, remote monitoring systems, metering (interval revenue, real-time), local and wide area networks, Web-based systems, smart controls, energy management/information systems with control and automation of building energy loads, and demand-response management with integration of real-time market pricing. For Phase II, BPL Global shall demonstrate the Phase I design for integrating and controlling the operation of more than 10 DER units, dispersed at various locations in one or more Independent System Operator (ISO) Control Areas, at

  1. Report: citizen participation as a part of integrated solid waste management: Porto Alegre case.

    Science.gov (United States)

    Bortoleto, Ana Paula; Hanaki, Keisuke

    2007-06-01

    This study presents the effects of citizen participation on integrated solid waste management. Porto Alegre was chosen as the area of study since its system is a good example for developing countries, based on the partnership between local government and the former scavengers' association that implements selective collection in the city. A life-cycle approach was used to estimate environmental loadings and economic costs based on solid waste generation, and a survey assessment tool was used to analyse social aspects. The results showed a decrease in environmental and economic impacts in the current situation, allowing Porto Alegre to have one of the most affordable integrated solid waste management systems in Brazil. The survey assessment pointed out that public campaign changed the perceptions and practices of most of Porto Alegre's citizens regarding solid waste management. On the other hand, it also pointed out that citizens need more education to increase their participation. Therefore, more research is needed to increase cooperation among all stakeholders, improve citizen participation, and consequently, further decrease the environmental impacts and economic costs.

  2. Hawaii Utility Integration Initiatives to Enable Wind (Wind HUI) Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Dora Nakafuji; Lisa Dangelmaier; Chris Reynolds

    2012-07-15

    To advance the state and nation toward clean energy, Hawaii is pursuing an aggressive Renewable Portfolio Standard (RPS), 40% renewable generation and 30% energy efficiency and transportation initiatives by 2030. Additionally, with support from federal, state and industry leadership, the Hawaii Clean Energy Initiative (HCEI) is focused on reducing Hawaii's carbon footprint and global warming impacts. To keep pace with the policy momentum and changing industry technologies, the Hawaiian Electric Companies are proactively pursuing a number of potential system upgrade initiatives to better manage variable resources like wind, solar and demand-side and distributed generation alternatives (i.e. DSM, DG). As variable technologies will continue to play a significant role in powering the future grid, practical strategies for utility integration are needed. Hawaiian utilities are already contending with some of the highest penetrations of renewables in the nation in both large-scale and distributed technologies. With island grids supporting a diverse renewable generation portfolio at penetration levels surpassing 40%, the Hawaiian utilities experiences can offer unique perspective on practical integration strategies. Efforts pursued in this industry and federal collaborative project tackled challenging issues facing the electric power industry around the world. Based on interactions with a number of western utilities and building on decades of national and international renewable integration experiences, three priority initiatives were targeted by Hawaiian utilities to accelerate integration and management of variable renewables for the islands. The three initiatives included: Initiative 1: Enabling reliable, real-time wind forecasting for operations by improving short-term wind forecasting and ramp event modeling capabilities with local site, field monitoring; Initiative 2: Improving operators situational awareness to variable resources via real-time grid condition

  3. National Acid Precipitation Assessment Program Report to Congress: An Integrated Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Uhart, M.; et al,

    2005-08-01

    Under Title IX of the 1990 Clean Air Act Amendments, Congress reauthorized the National Acid Precipitation Assessment Program (NAPAP) to continue coordinating acid rain research and monitoring, as it had done during the previous decade, and to provide Congress with periodic reports. In particular, Congress asked NAPAP to assess all available data and information to answer two questions: (1) What are the costs, benefits, and effectiveness of Title IV? This question addresses the costs and economic impacts of complying with the Acid Rain Program as well as benefit analyses associated with the various human health and welfare effects, including reduced visibility, damages to materials and cultural resources, and effects on ecosystems. (2) What reductions in deposition rates are needed to prevent adverse ecological effects? This complex questions addresses ecological systems and the deposition levels at which they experience harmful effects. The results of the assessment of the effects of Title IV and of the relationship between acid deposition rates and ecological effects were to be reported to Congress quadrennially, beginning with the 1996 report to Congress. The objective of this Report is to address the two main questions posed by Congress and fully communicate the results of the assessment to decision-makers. Given the primary audience, most of this report is not written as a technical document, although information supporting the conclusions is provided along with references.

  4. Solid Waste Integrated Forecast Technical (SWIFT) Report FY2001 to FY2046 Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    BARCOT, R.A.

    2000-08-31

    This report provides up-to-date life cycle information about the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. It includes: an overview of Hanford-wide solid waste to be managed by the WM Project; program-level and waste class-specific estimates; background information on waste sources; and comparisons to previous forecasts and other national data sources. This report does not include: waste to be managed by the Environmental Restoration (EM-40) contractor (i.e., waste that will be disposed of at the Environmental Restoration Disposal Facility (ERDF)); waste that has been received by the WM Project to date (i.e., inventory waste); mixed low-level waste that will be processed and disposed by the River Protection Program; and liquid waste (current or future generation). Although this report currently does not include liquid wastes, they may be added as information becomes available.

  5. Integrated data base report--1995: US spent nuclear fuel and radioactive waste inventories, projections, and characteristics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    The information in this report summarizes the U.S. Department of Energy (DOE) data base for inventories, projections, and characteristics of domestic spent nuclear fuel and radioactive waste. This report is updated annually to keep abreast of continual waste inventory and projection changes in both the government and commercial sectors. Baseline information is provided for DOE program planning purposes and to support DOE program decisions. Although the primary purpose of this document is to provide background information for program planning within the DOE community, it has also been found useful by state and local governments, the academic community, and some private citizens.

  6. Low-Cost Solar Array Project. Progress report 14, August 1979-December 1979 and proceedings of the 14th Project Integration Meeting

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    Progress made by the Low-Cost Solar Array Project during the period August through November 1979, is described. Progress on project analysis and integration; technology development in silicon material, large-area sheet silicon, and encapsulation; production process and equipment development; engineering, and operations, and the steps taken to integrate these efforts are detailed. A report on the Project Integration Meeting held December 5-6, 1979, including copies of the visual materials used, is presented.

  7. Integrated Thermal Treatment Systems study: US Department of Energy Internal Review Panel report

    Energy Technology Data Exchange (ETDEWEB)

    Cudahy, J.; Escarda, T.; Gimpel, R. [and others

    1995-04-01

    The U.S. Department of Energy`s (DOE) Office of Technology Development (OTD) commissioned two studies to uniformly evaluate nineteen thermal treatment technologies. These studies were called the Integrated Thermal Treatment System (ITTS) Phase I and Phase II. With the advice and guidance of the DOE Office of Environmental Management`s (EM`s) Mixed Waste Focus Group, OTD formed an ITTS Internal Review Panel, composed of scientists and engineers from throughout the DOE complex, the U.S. Environmental Protection Agency (EPA), the California EPA, and private experts. The Panel met from November 15-18, 1994, to review and comment on the ITTS studies, to make recommendations on the most promising thermal treatment systems for DOE mixed low level wastes (MLLW), and to make recommendations on research and development necessary to prove the performance of the technologies on MLLW.

  8. Modeling of integrated environmental control systems for coal-fired power plants. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Rubin, E.S.; Salmento, J.S.; Frey, H.C.; Abu-Baker, A.; Berkenpas, M.

    1991-05-01

    The Integrated Environmental Control Model (IECM) was designed to permit the systematic evaluation of environmental control options for pulverized coal-fired (PC) power plants. Of special interest was the ability to compare the performance and cost of advanced pollution control systems to ``conventional`` technologies for the control of particulate, SO{sub 2} and NO{sub x}. Of importance also was the ability to consider pre-combustion, combustion and post-combustion control methods employed alone or in combination to meet tough air pollution emission standards. Finally, the ability to conduct probabilistic analyses is a unique capability of the IECM. Key results are characterized as distribution functions rather than as single deterministic values. (VC)

  9. Fluor Daniel Hanford Inc. integrated safety management system phase 1 verification final report

    Energy Technology Data Exchange (ETDEWEB)

    PARSONS, J.E.

    1999-10-28

    The purpose of this review is to verify the adequacy of documentation as submitted to the Approval Authority by Fluor Daniel Hanford, Inc. (FDH). This review is not only a review of the Integrated Safety Management System (ISMS) System Description documentation, but is also a review of the procedures, policies, and manuals of practice used to implement safety management in an environment of organizational restructuring. The FDH ISMS should support the Hanford Strategic Plan (DOE-RL 1996) to safely clean up and manage the site's legacy waste; deploy science and technology while incorporating the ISMS theme to ''Do work safely''; and protect human health and the environment.

  10. Integrated coal preparation and CWF processing plant: Conceptual design and costing. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    McHale, E.T.; Paul, A.D.; Bartis, J.T. [Science Applications International Corp., McLean, VA (United States); Korkmaz, M. [Roberts and Schaefer Co., Salt Lake City, UT (United States)

    1992-12-01

    At the request of the US Department of Energy (DOE), Pittsburgh Energy Technology Center, a study was conducted to provide DOE with a reliable, documented estimate of the cost of producing coal-water fuel (CWF). The approach to the project was to specify a plant capacity and location, identify and analyze a suitable coal, and develop a conceptual design for an integrated coal preparation and CWF processing plant. Using this information, a definitive costing study was then conducted, on the basis of which an economic and sensitivity analysis was performed utilizing a financial evaluation model to determine a price for CWF in 1992. The design output of the integrated plant is 200 tons of coal (dry basis) per hour. Operating at a capacity factor of 83 percent, the baseline design yields approximately 1.5 million tons per year of coal on a dry basis. This is approximately equivalent to the fuel required to continuously generate 500 MW of electric power. The CWF produced by the plant is intended as a replacement for heavy oil or gas in electric utility and large industrial boilers. The particle size distribution, particularly the top size, and the ash content of the coal in the CWF are specified at significantly lower levels than is commonly found in typical pulverized coal grinds. The particle top size is 125 microns (vs typically 300m{mu} for pulverized coal) and the coal ash content is 3.8 percent. The lower top size is intended to promote complete carbon burnout at less derating in boilers that are not designed for coal firing. The reduced mineral matter content will produce ash of very fine particle size during combustion, which leads to less impaction and reduced fouling of tubes in convective passages.

  11. Carolina Offshore Wind Integration Case Study: Phases I and II Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Fallon, Christopher [Duke Energy Business Services, LLC, Charlotte, NC (United States); Piper, Orvane [Duke Energy Business Services, LLC, Charlotte, NC (United States); Hazelip, William [Duke Energy Business Services, LLC, Charlotte, NC (United States); Zhao, Yishan [Duke Energy Business Services, LLC, Charlotte, NC (United States); Salvador, Lisa [Duke Energy Business Services, LLC, Charlotte, NC (United States); Pruitt, Tom [Duke Energy Business Services, LLC, Charlotte, NC (United States); Peterson, Jeffrey [Duke Energy Business Services, LLC, Charlotte, NC (United States); Ashby, Rebecca [Duke Energy Business Services, LLC, Charlotte, NC (United States); Pierce, Bob [Duke Energy Business Services, LLC, Charlotte, NC (United States); Burner, Bob [Duke Energy Business Services, LLC, Charlotte, NC (United States); Daniel, John [ABB, Inc., Cary, NC (United States); Zhu, Jinxiang [ABB, Inc., Cary, NC (United States); Moore, Maria [ABB, Inc., Cary, NC (United States); Liu, Shu [ABB, Inc., Cary, NC (United States); Pennock, Ken [AWS Truepower, LLC, Albany, NY (United States); Frank, Jaclyn [AWS Truepower, LLC, Albany, NY (United States); Ibanez, Eduardo [National Renewable Energy Lab. (NREL), Golden, CO (United States); Heaney, Michael [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bloom, Aaron [National Renewable Energy Lab. (NREL), Golden, CO (United States); Zhang, Yingchen [National Renewable Energy Lab. (NREL), Golden, CO (United States); Elliott, Dennis [National Renewable Energy Lab. (NREL), Golden, CO (United States); Seim, Harvey E. [Univ. of North Carolina, Chapel Hill, NC (United States)

    2015-04-30

    Duke Energy performed a phase 1 study to assess the impact of offshore wind development in the waters off the coasts of North Carolina and South Carolina. The study analyzed the impacts to the Duke Energy Carolinas electric power system of multiple wind deployment scenarios. Focusing on an integrated utility system in the Carolinas provided a unique opportunity to assess the impacts of offshore wind development in a region that has received less attention regarding renewables than others in the US. North Carolina is the only state in the Southeastern United States that currently has a renewable portfolio standard (RPS) which requires that 12.5% of the state’s total energy requirements be met with renewable resources by 2021. 12.5% of the state’s total energy requirements in 2021 equates to approximately 17,000 GWH of energy needed from renewable resources. Wind resources represent one of the ways to potentially meet this requirement. The study builds upon and augments ongoing work, including a study by UNC to identify potential wind development sites and the analysis of impacts to the regional transmission system performed by the NCTPC, an Order 890 planning entity of which DEC is a member. Furthermore, because the region does not have an independent system operator (ISO) or regional transmission organization (RTO), the study will provide additional information unique to non-RTO/ISO systems. The Phase 2 study builds on the results of Phase 1 and investigates the dynamic stability of the electrical network in Task 4, the operating characteristics of the wind turbines as they impact operating reserve requirements of the DEC utility in Task 5, and the production cost of integrating the offshore wind resources into the DEC generation fleet making comparisons to future planned operation without the addition of the wind resources in Task 6.

  12. Electric utility system planning studies for OTEC power integration. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-11-30

    Florida Power Corporation (FPC) conducted an evaluation of the possible integration of OTEC into the FPC system. Existing system planning procedures, assumptions, and corporate financial criteria for planning new generating capacity were used without modification. A baseline configuration for an OTEC plant was developed for review with standard planning procedures. The OTEC plant characteristics and costs were incorporated in considerable detail. These basic inputs were examined using the FPC system planning methods. It was found that with the initial set of conditions, OTEC would not be economically viable. Using the same system planning procedures, a number of adjustments were made to the key study assumptions. It was found that two considerations dominate the analysis; the assumed rate of fuel cost escalation, and the projected capital cost of the OTEC plant. The analysis produced a parametric curve: on one hand, if fuel costs were to escalate at a rate greater than assumed (12% vs the assumed 5% for coal), and if no change were made to the OTEC input assumptions, the basic economic competitive criteria would be equivalent to the principal alternative, coal fueled plants. Conversely, if the projected cost of the OTEC plant were to be reduced from the assumed $2256/kW to $1450/kW, the economic competitiveness criterion would be satisfied. After corporate financial analysis, it was found that even if the cost competitive criterion were to be reached, the plan including OTEC could not be financed by Florida Power Corporation. Since, under the existing set of conditions for financing new plant capital requirements, FPC could not construct an OTEC plant, some other means of ownership would be necessary to integrate OTEC into the FPC system. An alternative such as a third party owning the plant and selling power to FPC, might prove attractive. (WHK)

  13. Integrating and Differentiating Meanings in Tweeting about the fifth Intergovernmental Panel on Climate Change (IPCC) report

    NARCIS (Netherlands)

    Holmberg, K.; Hellsten, I.

    2016-01-01

    The publication of the fifth Intergovernmental Panel on Climate Change (IPCC) Working Group 1 report in September 2013 was highly debated on Twitter. In this paper we focused on tweets that mention “IPCC”, and in particular the content and sentiment of the tweets sent by tweeters that were

  14. Integrating and Differentiating Meanings in Tweeting about the fifth Intergovernmental Panel on Climate Change (IPCC) report

    NARCIS (Netherlands)

    Holmberg, K.; Hellsten, I.

    2016-01-01

    The publication of the fifth Intergovernmental Panel on Climate Change (IPCC) Working Group 1 report in September 2013 was highly debated on Twitter. In this paper we focused on tweets that mention “IPCC”, and in particular the content and sentiment of the tweets sent by tweeters that were identifie

  15. Integral quantification accuracy estimation for reporter ion-based quantitative proteomics (iQuARI).

    Science.gov (United States)

    Vaudel, Marc; Burkhart, Julia M; Radau, Sonja; Zahedi, René P; Martens, Lennart; Sickmann, Albert

    2012-10-05

    With the increasing popularity of comparative studies of complex proteomes, reporter ion-based quantification methods such as iTRAQ and TMT have become commonplace in biological studies. Their appeal derives from simple multiplexing and quantification of several samples at reasonable cost. This advantage yet comes with a known shortcoming: precursors of different species can interfere, thus reducing the quantification accuracy. Recently, two methods were brought to the community alleviating the amount of interference via novel experimental design. Before considering setting up a new workflow, tuning the system, optimizing identification and quantification rates, etc. one legitimately asks: is it really worth the effort, time and money? The question is actually not easy to answer since the interference is heavily sample and system dependent. Moreover, there was to date no method allowing the inline estimation of error rates for reporter quantification. We therefore introduce a method called iQuARI to compute false discovery rates for reporter ion based quantification experiments as easily as Target/Decoy FDR for identification. With it, the scientist can accurately estimate the amount of interference in his sample on his system and eventually consider removing shadows subsequently, a task for which reporter ion quantification might not be the solution of choice.

  16. [Lactobacillus Rhamnosus sepsis in a preterm infant associated with probiotic integrator use: a case report.

    Science.gov (United States)

    Molinaro, Manuela; Aiazzi, Massimo; La Torre, Antonio; Cini, Elisabetta; Banfi, Roberto

    2016-09-01

    Preterm infants are at high risk of neonatal sepsis. We report a case of a preterm infant under prophylaxis with Lactobacillus Rhamnosus for necrotizing enterocolitis; the child develops neonatal sepsis by Lactobacillus Rhamnosus. The infection is improved after probiotic withdrawal and had complete remission after 20 days of specific antibiotic therapy.

  17. NREL/SCE High-Penetration PV Integration Project: Report on Field Demonstration of Advanced Inverter Functionality in Fontana, CA

    Energy Technology Data Exchange (ETDEWEB)

    Mather, B.

    2014-08-01

    The National Renewable Energy Laboratory/Southern California Edison High-Penetration PV Integration Project is (1) researching the distribution system level impacts of high-penetration photovoltaic (PV) integration, (2) determining mitigation methods to reduce or eliminate those impacts, and (3) seeking to demonstrate these mitigation methods on actual high-penetration PV distribution circuits. This report describes a field demonstration completed during the fall of 2013 on the Fontana, California, study circuit, which includes a total of 4.5 MW of interconnected utility-scale rooftop PV systems. The demonstration included operating a 2-MW PV system at an off-unity power factor that had been determined during previously completed distribution system modeling and PV impact assessment analyses. Data on the distribution circuit and PV system operations were collected during the 2-week demonstration period. This demonstration reinforces the findings of previous laboratory testing that showed that utility-scale PV inverters are capable of operating at off-unity power factor to mitigate PV impacts; however, because of difficulties setting and retaining PV inverter power factor set points during the field demonstration, it was not possible to demonstrate the effectiveness of off-unity power factor operation to mitigate the voltage impacts of high-penetration PV integration. Lessons learned from this field demonstration are presented to inform future field demonstration efforts.

  18. River Protection Project Integrated safety management system phase II verification report, volumes I and II - 8/19/99

    Energy Technology Data Exchange (ETDEWEB)

    SHOOP, D.S.

    1999-09-10

    The Department of Energy policy (DOE P 450.4) is that safety is integrated into all aspects of the management and operations of its facilities. In simple and straightforward terms, the Department will ''Do work safely.'' The purpose of this River Protection Project (RPP) Integrated Safety Management System (ISMS) Phase II Verification was to determine whether ISMS programs and processes are implemented within RFP to accomplish the goal of ''Do work safely.'' The goal of an implemented ISMS is to have a single integrated system that includes Environment, Safety, and Health (ES&H) requirements in the work planning and execution processes to ensure the protection of the worker, public, environment, and federal property over the RPP life cycle. The ISMS is comprised of the (1) described functions, components, processes, and interfaces (system map or blueprint) and (2) personnel who are executing those assigned roles and responsibilities to manage and control the ISMS. Therefore, this review evaluated both the ''paper'' and ''people'' aspects of the ISMS to ensure that the system is implemented within RPP. Richland Operations Office (RL) conducted an ISMS Phase I Verification of the TWRS from September 28-October 9, 1998. The resulting verification report recommended that TWRS-RL and the contractor proceed with Phase II of ISMS verification given that the concerns identified from the Phase I verification review are incorporated into the Phase II implementation plan.

  19. Solid waste integrated forecast technical (SWIFT) report: FY1997 to FY 2070, Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Valero, O.J.; Templeton, K.J.; Morgan, J.

    1997-01-07

    This web site provides an up-to-date report on the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. It includes: an overview of Hanford-wide solid waste to be managed by the WM Project; program-level and waste class-specific estimates; background information on waste sources; and comparisons with previous forecasts and with other national data sources. This web site does not include: liquid waste (current or future generation); waste to be managed by the Environmental Restoration (EM-40) contractor (i.e., waste that will be disposed of at the Environmental Restoration Disposal Facility (ERDF)); or waste that has been received by the WM Project to date (i.e., inventory waste). The focus of this web site is on low-level mixed waste (LLMW), and transuranic waste (both non-mixed and mixed) (TRU(M)). Some details on low-level waste and hazardous waste are also provided. Currently, this web site is reporting data th at was requested on 10/14/96 and submitted on 10/25/96. The data represent a life cycle forecast covering all reported activities from FY97 through the end of each program's life cycle. Therefore, these data represent revisions from the previous FY97.0 Data Version, due primarily to revised estimates from PNNL. There is some useful information about the structure of this report in the SWIFT Report Web Site Overview.

  20. {sup 210}Po as a long-term integrating radon indicator in the indoor environment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    Exposure to radon (Rn-222) decay products in the indoor environment is suspected of being a significant lung cancer agent in many countries. But quantification of the contemporary lung cancer risk (i.e. probability) on an individual basis is not an easy task. Only past exposures are relevant and assessing individual exposures in retrospect is associated with large uncertainties, if possible at all. One way to extend the validity of contemporary measurements to past decades is to measure long-lived decay products of radon, the long-lived radon daughters. After our laboratory had exemplified the correlation between implanted Po-210 and the estimated radon exposures in six different dwellings, the US Department of Energy and the Swedish Radiation Protection Institute granted funds for a one-year study, ``{sup 210}Po as a Long-Term Integrating Radon Indicator in the Indoor Environment.`` In this report the work performed under these two contracts is reported.