WorldWideScience

Sample records for replication-associated strand asymmetries

  1. ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks

    International Nuclear Information System (INIS)

    Köcher, Sabrina; Spies-Naumann, Anja; Kriegs, Malte; Dahm-Daphi, Jochen; Dornreiter, Irena

    2013-01-01

    Purpose: DNA replication is a promising target for anti-cancer therapies. Therefore, the understanding of replication-associated DNA repair mechanisms is of great interest. One key factor of DNA double-strand break (DSB) repair is the PIK kinase Ataxia-Telangiectasia Mutated (ATM) but it is still unclear whether ATM is involved in the repair of replication-associated DSBs. Here, we focused on the involvement of ATM in homology-directed repair (HDR) of indirect DSBs associated with replication. Material and methods: Experiments were performed using ATM-deficient and -proficient human cells. Replication-associated DSBs were induced with Topotecan (TPT) and compared with γ-irradiation (IR). Cell survival was measured by clonogenic assay. Overall DSB repair and HDR were evaluated by detecting residual γH2AX/53BP1 and Rad51 foci, respectively. Cell cycle distribution was analysed by flow cytometry and protein expression by Western blot. Results: ATM-deficiency leads to enhanced numbers of residual DSBs, resulting in a pronounced S/G2-block and decreased survival upon TPT-treatment. In common with IR, persisting Rad51 foci were detected following TPT-treatment. Conclusions: These results demonstrate that ATM is essentially required for the completion of HR-mediated repair of TPT-induced DSBs formed indirectly at replication forks

  2. New views on strand asymmetry in insect mitochondrial genomes.

    Directory of Open Access Journals (Sweden)

    Shu-Jun Wei

    Full Text Available Strand asymmetry in nucleotide composition is a remarkable feature of animal mitochondrial genomes. Understanding the mutation processes that shape strand asymmetry is essential for comprehensive knowledge of genome evolution, demographical population history and accurate phylogenetic inference. Previous studies found that the relative contributions of different substitution types to strand asymmetry are associated with replication alone or both replication and transcription. However, the relative contributions of replication and transcription to strand asymmetry remain unclear. Here we conducted a broad survey of strand asymmetry across 120 insect mitochondrial genomes, with special reference to the correlation between the signs of skew values and replication orientation/gene direction. The results show that the sign of GC skew on entire mitochondrial genomes is reversed in all species of three distantly related families of insects, Philopteridae (Phthiraptera, Aleyrodidae (Hemiptera and Braconidae (Hymenoptera; the replication-related elements in the A+T-rich regions of these species are inverted, confirming that reversal of strand asymmetry (GC skew was caused by inversion of replication origin; and finally, the sign of GC skew value is associated with replication orientation but not with gene direction, while that of AT skew value varies with gene direction, replication and codon positions used in analyses. These findings show that deaminations during replication and other mutations contribute more than selection on amino acid sequences to strand compositions of G and C, and that the replication process has a stronger affect on A and T content than does transcription. Our results may contribute to genome-wide studies of replication and transcription mechanisms.

  3. Nucleotide compositional asymmetry between the leading and lagging strands of eubacterial genomes

    KAUST Repository

    Qu, Hongzhu; Wu, Hao; Zhang, Tongwu; Zhang, Zhang; Hu, Songnian; Yu, Jun

    2010-01-01

    Nucleotide compositional asymmetry (NCA) between leading and lagging strands (LeS and LaS) is dynamic and diverse among eubacterial genomes due to different mutation and selection forces. A thorough investigation is needed in order to study the relationship between nucleotide composition dynamics and gene distribution biases. Based on a collection of 364 eubacterial genomes that were grouped according to a DnaE-based scheme (DnaE1-DnaE1, DnaE2-DnaE1, and DnaE3-PolC), we investigated NCA and nucleotide composition gradients at three codon positions and found that there was universal G-enrichment on LeS among all groups. This was due to a strong selection for G-heading (codon position1 or cp1) codons and mutation pressure that led to more G-ending (cp3) codons. Moreover, a slight T-enrichment of LeS due to the mutation of cytosine deamination at cp3 was universal among DnaE1-DnaE1 and DnaE2-DnaE1 genomes, but was not clearly seen among DnaE3-PolC genomes, in which A-enrichment of LeS was proposed to be the effect of selections unique to polC and a mutation bias toward A-richness at cp1 that may be a result of transcription-coupled DNA repair mechanisms. Furthermore, strand-biased gene distribution enhances the purine-richness of LeS for DnaE3-PolC genomes and T-richness of LeS for DnaE1-DnaE1 and DnaE2-dnaE1 genomes. © 2010 Institut Pasteur.

  4. Nucleotide compositional asymmetry between the leading and lagging strands of eubacterial genomes

    KAUST Repository

    Qu, Hongzhu

    2010-12-01

    Nucleotide compositional asymmetry (NCA) between leading and lagging strands (LeS and LaS) is dynamic and diverse among eubacterial genomes due to different mutation and selection forces. A thorough investigation is needed in order to study the relationship between nucleotide composition dynamics and gene distribution biases. Based on a collection of 364 eubacterial genomes that were grouped according to a DnaE-based scheme (DnaE1-DnaE1, DnaE2-DnaE1, and DnaE3-PolC), we investigated NCA and nucleotide composition gradients at three codon positions and found that there was universal G-enrichment on LeS among all groups. This was due to a strong selection for G-heading (codon position1 or cp1) codons and mutation pressure that led to more G-ending (cp3) codons. Moreover, a slight T-enrichment of LeS due to the mutation of cytosine deamination at cp3 was universal among DnaE1-DnaE1 and DnaE2-DnaE1 genomes, but was not clearly seen among DnaE3-PolC genomes, in which A-enrichment of LeS was proposed to be the effect of selections unique to polC and a mutation bias toward A-richness at cp1 that may be a result of transcription-coupled DNA repair mechanisms. Furthermore, strand-biased gene distribution enhances the purine-richness of LeS for DnaE3-PolC genomes and T-richness of LeS for DnaE1-DnaE1 and DnaE2-dnaE1 genomes. © 2010 Institut Pasteur.

  5. Diverse circular replication-associated protein encoding viruses circulating in invertebrates within a lake ecosystem.

    Science.gov (United States)

    Dayaram, Anisha; Galatowitsch, Mark L; Argüello-Astorga, Gerardo R; van Bysterveldt, Katherine; Kraberger, Simona; Stainton, Daisy; Harding, Jon S; Roumagnac, Philippe; Martin, Darren P; Lefeuvre, Pierre; Varsani, Arvind

    2016-04-01

    Over the last five years next-generation sequencing has become a cost effective and efficient method for identifying known and unknown microorganisms. Access to this technique has dramatically changed the field of virology, enabling a wide range of environmental viral metagenome studies to be undertaken of organisms and environmental samples from polar to tropical regions. These studies have led to the discovery of hundreds of highly divergent single stranded DNA (ssDNA) virus-like sequences encoding replication-associated proteins. Yet, few studies have explored how viruses might be shared in an ecosystem through feeding relationships. Here we identify 169 circular molecules (160 CRESS DNA molecules, nine circular molecules) recovered from a New Zealand freshwater lake, that we have tentatively classified into 51 putatively novel species and five previously described species (DflaCV-3, -5, -6, -8, -10). The CRESS DNA viruses identified in this study were recovered from molluscs (Echyridella menzeisii, Musculium novaezelandiae, Potamopyrgus antipodarum and Physella acuta) and insect larvae (Procordulia grayi, Xanthocnemis zealandica, and Chironomus zealandicus) collected from Lake Sarah, as well as from the lake water and benthic sediments. Extensive diversity was observed across most CRESS DNA molecules recovered. The putative capsid protein of one viral species was found to be most similar to those of members of the Tombusviridae family, thus expanding the number of known RNA-DNA hybrid viruses in nature. We noted a strong association between the CRESS DNA viruses and circular molecules identified in the water and browser organisms (C. zealandicus, P. antipodarum and P. acuta), and between water sediments and undefended prey species (C. zealandicus). However, we were unable to find any significant correlation of viral assemblages to the potential feeding relationships of the host aquatic invertebrates. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Nasopupillary asymmetry.

    Science.gov (United States)

    Arenas, Eduardo; Muñoz, Diana; Matheus, Evelyn; Morales, Diana

    2014-01-01

    To establish the prevalence of nasopupillary asymmetry (difference in nasopupillary distances) in the population and its relation with the interpupillary distance. A retrospective descriptive study was conducted by reviewing of 1262 medical records. The values of nasopupillary asymmetry and the interpupillary distance were obtained. A statistical analysis was made and the correlation between these variables was established. Seventy-nine percent of the population presented some degree of nasopupillary asymmetry. The interpupillary distance had a very low correlation with the nasopupillary asymmetry (r = 0.074, P = 0.0). It is advisable to use the nasopupillary distance of each eye as a standard measurement.

  7. Diverse replication-associated protein encoding circular DNA viruses in guano samples of Central-Eastern European bats.

    Science.gov (United States)

    Kemenesi, Gábor; Kurucz, Kornélia; Zana, Brigitta; Földes, Fanni; Urbán, Péter; Vlaschenko, Anton; Kravchenko, Kseniia; Budinski, Ivana; Szodoray-Parádi, Farkas; Bücs, Szilárd; Jére, Csaba; Csősz, István; Szodoray-Parádi, Abigél; Estók, Péter; Görföl, Tamás; Boldogh, Sándor; Jakab, Ferenc

    2018-03-01

    Circular replication-associated protein encoding single-stranded DNA (CRESS DNA) viruses are increasingly recognized worldwide in a variety of samples. Representative members include well-described veterinary pathogens with worldwide distribution, such as porcine circoviruses or beak and feather disease virus. In addition, numerous novel viruses belonging to the family Circoviridae with unverified pathogenic roles have been discovered in different human samples. Viruses of the family Genomoviridae have also been described as being highly abundant in different faecal and environmental samples, with case reports showing them to be suspected pathogens in human infections. In order to investigate the genetic diversity of these viruses in European bat populations, we tested guano samples from Georgia, Hungary, Romania, Serbia and Ukraine. This resulted in the detection of six novel members of the family Circoviridae and two novel members of the family Genomoviridae. Interestingly, a gemini-like virus, namely niminivirus, which was originally found in raw sewage samples in Nigeria, was also detected in our samples. We analyzed the nucleotide composition of members of the family Circoviridae to determine the possible host origins of these viruses. This study provides the first dataset on CRESS DNA viruses of European bats, and members of several novel viral species were discovered.

  8. Inclusive asymmetries

    International Nuclear Information System (INIS)

    Peterson, E.A.

    1977-01-01

    The polarized proton beam was used to measure left-right asymmetries for the reactions p + p → p, K +- , π +- + anything and also some information on the reaction p + n → p, K +- , π + + anything are presented. The incident momentum is 11.8 GeV/c. The data are preliminary. Six references

  9. Puzzling asymmetries

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    In a recently published paper, the LHCb Collaboration has reported on a possible deviation from the Standard Model. Theorists are now working to calculate precisely this effect and to evaluate the implications that such unexpected result could have on the established theory.   The Standard Model is able to predict the decay rates of particles with high precision. In most cases, experimentalists confirm the value predicted by theory and the figure is added to the official publications. However, this time, things seem to have taken a different route. Studying data collected in 2011, the LHCb Collaboration found that in a specific decay – a B particle transforming into a K particle plus two charged muons (B -> Kμ-μ+) – the branching ratio of the neutral B in the corresponding decay (i.e. B0 -> K0μ-μ+) is different from that of the positively charged B (i.e. B+ -> K+μ-μ+). Such an “isospin asymmetry&rdquo...

  10. Connecting localized DNA strand displacement reactions

    Science.gov (United States)

    Mullor Ruiz, Ismael; Arbona, Jean-Michel; Lad, Amitkumar; Mendoza, Oscar; Aimé, Jean-Pierre; Elezgaray, Juan

    2015-07-01

    Logic circuits based on DNA strand displacement reactions have been shown to be versatile enough to compute the square root of four-bit numbers. The implementation of these circuits as a set of bulk reactions faces difficulties which include leaky reactions and intrinsically slow, diffusion-limited reaction rates. In this paper, we consider simple examples of these circuits when they are attached to platforms (DNA origamis). As expected, constraining distances between DNA strands leads to faster reaction rates. However, it also induces side-effects that are not detectable in the solution-phase version of this circuitry. Appropriate design of the system, including protection and asymmetry between input and fuel strands, leads to a reproducible behaviour, at least one order of magnitude faster than the one observed under bulk conditions.Logic circuits based on DNA strand displacement reactions have been shown to be versatile enough to compute the square root of four-bit numbers. The implementation of these circuits as a set of bulk reactions faces difficulties which include leaky reactions and intrinsically slow, diffusion-limited reaction rates. In this paper, we consider simple examples of these circuits when they are attached to platforms (DNA origamis). As expected, constraining distances between DNA strands leads to faster reaction rates. However, it also induces side-effects that are not detectable in the solution-phase version of this circuitry. Appropriate design of the system, including protection and asymmetry between input and fuel strands, leads to a reproducible behaviour, at least one order of magnitude faster than the one observed under bulk conditions. Electronic supplementary information (ESI) available. See DOI: 10.1039/C5NR02434J

  11. Novel Single-Stranded DNA Virus Genomes Recovered from Chimpanzee Feces Sampled from the Mambilla Plateau in Nigeria

    Science.gov (United States)

    Walters, Matthew; Bawuro, Musa; Christopher, Alfred; Knight, Alexander; Kraberger, Simona; Stainton, Daisy; Chapman, Hazel

    2017-01-01

    ABSTRACT Metagenomic approaches are rapidly expanding our knowledge of the diversity of viruses. In the fecal matter of Nigerian chimpanzees we recovered three gokushovirus genomes, one circular replication-associated protein encoding single-stranded DNA virus (CRESS), and a CRESS DNA molecule. PMID:28254982

  12. Stranded Specimen Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Mammal and Turtle Division collects data about individual cetaceans and sea turtles that come ashore, or strand on the beach. The date and location of...

  13. Alaska Beluga Strandings

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NMFS is mandated by the Marine Mammal Protection Act (MMPA) to collect reports of marine mammal stranding events. This particular catalogue item is specific to the...

  14. Fluctuating Asymmetry and Intelligence

    Science.gov (United States)

    Bates, Timothy C.

    2007-01-01

    The general factor of mental ability ("g") may reflect general biological fitness. If so, "g"-loaded measures such as Raven's progressive matrices should be related to morphological measures of fitness such as fluctuating asymmetry (FA: left-right asymmetry of a set of typically left-right symmetrical body traits such as finger…

  15. Lowering of Asymmetry

    Indian Academy of Sciences (India)

    et al. 2002, 2003). The N–S asymmetries of different activity manifestations have been .... 2006), the N–S asymmetry of FISXR. (Joshi et al. 2015). In the present study, we use this ..... Howe, R., Christensen-Dalsgaard, J., Hill, F., Komm, R. W.,.

  16. Strand SPA & Konverentsikeskus

    Index Scriptorium Estoniae

    2008-01-01

    Strand SPA & Konverentsikeskus on Pärnu suurim äri- ja konverentsiklientidele suunatud hotell, mis klientide seas on hinnatud just selle kompleksuse tõttu, kuna kõik, mida külaline vajab ja soovib, on olemas ühe katuse all

  17. LHC superconducting strand

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    This cross-section through a strand of superconducting matieral as used in the LHC shows the 8000 Niobium-Titanium filaments embedded like a honeycomb in copper. When cooled to 1.9 degrees above absolute zero in the LHC accelerator, these filaments will have zero resistance and so will carry a high electric current with no energy loss.

  18. An unusual internal ribosomal entry site of inverted symmetry directs expression of a potato leafroll polerovirus replication-associated protein

    Science.gov (United States)

    Jaag, Hannah Miriam; Kawchuk, Lawrence; Rohde, Wolfgang; Fischer, Rainer; Emans, Neil; Prüfer, Dirk

    2003-01-01

    Potato leafroll polerovirus (PLRV) genomic RNA acts as a polycistronic mRNA for the production of proteins P0, P1, and P2 translated from the 5′-proximal half of the genome. Within the P1 coding region we identified a 5-kDa replication-associated protein 1 (Rap1) essential for viral multiplication. An internal ribosome entry site (IRES) with unusual structure and location was identified that regulates Rap1 translation. Core structural elements for internal ribosome entry include a conserved AUG codon and a downstream GGAGAGAGAGG motif with inverted symmetry. Reporter gene expression in potato protoplasts confirmed the internal ribosome entry function. Unlike known IRES motifs, the PLRV IRES is located completely within the coding region of Rap1 at the center of the PLRV genome. PMID:12835413

  19. Sea Turtle Stranding Network Reports

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Sea Turtle Stranding and Salvage Network (STSSN) was formally established in 1980 to collect information on and document the stranding of marine turtles along...

  20. Different responses to muon implantation in single- and double-stranded DNA

    International Nuclear Information System (INIS)

    Hubbard, Penny L.; Tani, Akiko; Oganesyan, Vasily S.; Butt, Julea N.; Cottrell, Stephen P.; Jayasooriya, Upali A.

    2006-01-01

    A model-free analysis of the longitudinal muon spin relaxation of muons implanted into single- and double-stranded DNA samples is reported. These samples show distinctly different responses to implanted muons with discontinuities of the integrated asymmetries at temperatures where these molecules are likely to have onset of molecular and electron dynamics

  1. Symmetry, asymmetry and dissymmetry

    International Nuclear Information System (INIS)

    Wackenheim, A.; Zollner, G.

    1987-01-01

    The authors discuss the concept of symmetry and defect of symmetry in radiological imaging and recall the definition of asymmetry (congenital or constitutional) and dissymmetry (acquired). They then describe a rule designed for the cognitive method of automatic evaluation of shape recognition data and propose the use of reversal symmetry [fr

  2. Detection symmetry and asymmetry

    NARCIS (Netherlands)

    du Buf, J.M.H.

    1991-01-01

    Experiments were performed on the detection symmetry and asymmetry of incremental and decremental disks, as a function of both disk diameter and duration. It was found that, for a background luminance of 300cd.m-2, thresholds of dynamic (briefly presented) foveal disks are symmetrical for all

  3. Stranded costs and exit fees

    International Nuclear Information System (INIS)

    2002-01-01

    The New Brunswick Market Design Committee has been directed to examine the issue of stranded costs since it is a major component of restructuring within the electricity sector. When regulated monopolies are faced with competition, they could find that some of their embedded costs cannot be recovered. These costs are referred to as stranded costs. Common sources include large capital investments in uneconomic plants or expensive power purchase contracts or fuel supply contracts. In general, stranded costs do not include gains or losses associated with normal business risks experienced by regulated utilities. This report presents recommendations for mitigation of stranded costs, valuation methodologies and cost-recovery mechanisms. It also presents a summary of experience with stranded costs in other jurisdictions such as California, Rhode Island, Pennsylvania and Ontario. Stranded costs are often recovered through an obligatory charge on all customers, particularly in jurisdictions where retail competition exists. In the New Brunswick market, however, the only customers who can create stranded costs are those eligible to choose their own suppliers. It is argued that since most customers will not have a choice of electricity suppliers, they cannot generate stranded costs and therefore, should not have to pay costs stranded by others. A method to quantify stranded costs is presented, along with a review of transmission-related stranded costs in New Brunswick. Expansion of self-generation in New Brunswick could strand transmission assets. Currently, self-generators only contribute a small amount to fixed charges of the transmission system. However, under new recommended tariffs, the amount could increase. It is likely that the net amount of stranded transmission costs will not be large. 2 refs., 1 fig

  4. Asymmetry, Symmetry and Beauty

    Directory of Open Access Journals (Sweden)

    Abbe R. Kopra

    2010-07-01

    Full Text Available Asymmetry and symmetry coexist in natural and human processes.  The vital role of symmetry in art has been well demonstrated. This article highlights the complementary role of asymmetry. Further we show that the interaction of asymmetric action (recursion and symmetric opposition (sinusoidal waves are instrumental in generating creative features (relatively low entropy, temporal complexity, novelty (less recurrence in the data than in randomized copies and complex frequency composition. These features define Bios, a pattern found in musical compositions and in poetry, except for recurrence instead of novelty. Bios is a common pattern in many natural and human processes (quantum processes, the expansion of the universe, gravitational waves, cosmic microwave background radiation, DNA, physiological processes, animal and human populations, and economic time series. The reduction in entropy is significant, as it reveals creativity and contradicts the standard claim of unavoidable decay towards disorder. Artistic creations capture fundamental features of the world.

  5. Information Asymmetry in Federations

    Directory of Open Access Journals (Sweden)

    Alexander Mikhailovich Libman

    2014-12-01

    Full Text Available The paper investigates the problems of information transmission between levels of government in a federal state. The central government in a federation typically faces serious difficulties while collecting information on economic and political situation in the regions. There are two types of problems: lack of incentives for the regions to accurately collect information and strategic manipulation of information, which are discussed in the paper along with possible solutions. In particular, overcoming information asymmetry would require the development of national parties or informal coalitions of bureaucrats and politicians of the center and of the regions, creating incentives for regional politicians to back the successful functioning of the federal level. Furthermore, the paper discusses the issue of «informal decentralization», which emerges as a result of information asymmetry, and its consequences for the functioning of a federal state, including both advantages and disadvantages. We conclude that under information asymmetry the organization of the federation will inevitably turn into an issue of permanent negotiations and bargaining between the center and the regions, which functions as the information acquisition tool for optimal allocation of authorities in a federation

  6. Bessel Weighted Asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Avakian, Harut [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Gamberg, Leonard [Pennsylvania State Univ., University Park, PA (United States); Rossi, Patrizia [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Prokudin, Alexei [Pennsylvania State Univ., University Park, PA (United States)

    2016-05-01

    We review the concept of Bessel weighted asymmetries for semi-inclusive deep inelastic scattering and focus on the cross section in Fourier space, conjugate to the outgoing hadron’s transverse momentum, where convolutions of transverse momentum dependent parton distribution functions and fragmentation functions become simple products. Individual asymmetric terms in the cross section can be projected out by means of a generalized set of weights involving Bessel functions. The procedure is applied to studies of the double longitudinal spin asymmetry in semi-inclusive deep inelastic scattering using a new dedicated Monte Carlo generator which includes quark intrinsic transverse momentum within the generalized parton model. We observe a few percent systematic offset of the Bessel-weighted asymmetry obtained from Monte Carlo extraction compared to input model calculations, which is due to the limitations imposed by the energy and momentum conservation at the given energy and hard scale Q2. We find that the Bessel weighting technique provides a powerful and reliable tool to study the Fourier transform of TMDs with controlled systematics due to experimental acceptances and resolutions with different TMD model inputs.

  7. Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage ▿

    Science.gov (United States)

    Foster, Steven S.; Balestrini, Alessia; Petrini, John H. J.

    2011-01-01

    The Mre11 complex is a central component of the DNA damage response, with roles in damage sensing, molecular bridging, and end resection. We have previously shown that in Saccharomyces cerevisiae, Ku70 (yKu70) deficiency reduces the ionizing radiation sensitivity of mre11Δ mutants. In this study, we show that yKu70 deficiency suppressed the camptothecin (CPT) and methyl methanesulfonate (MMS) sensitivity of nuclease-deficient mre11-3 and sae2Δ mutants in an Exo1-dependent manner. CPT-induced G2/M arrest, γ-H2AX persistence, and chromosome breaks were elevated in mre11-3 mutants. These outcomes were reduced by yKu70 deficiency. Given that the genotoxic effects of CPT are manifest during DNA replication, these data suggest that Ku limits Exo1-dependent double-strand break (DSB) resection during DNA replication, inhibiting the initial processing steps required for homology-directed repair. We propose that Mre11 nuclease- and Sae2-dependent DNA end processing, which initiates DSB resection prevents Ku from engaging DSBs, thus promoting Exo1-dependent resection. In agreement with this idea, we show that Ku affinity for binding to short single-stranded overhangs is much lower than for blunt DNA ends. Collectively, the data define a nonhomologous end joining (NHEJ)-independent, S-phase-specific function of the Ku heterodimer. PMID:21876003

  8. Analysis of DNA replication associated chromatin decondensation: in vivo assay for understanding chromatin remodeling mechanisms of selected proteins.

    Science.gov (United States)

    Borysov, Sergiy; Bryant, Victoria L; Alexandrow, Mark G

    2015-01-01

    mechanisms underlying DNA replication associated chromatin accessibility, this unique and powerful experimental system has the propensity to be a valuable tool for understanding chromatin remodeling mechanisms orchestrated by other cellular processes such as DNA repair, recombination, mitotic chromosome condensation, or other chromosome dynamics involving chromatin alterations and accessibility.

  9. Matter-antimatter asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The Conference is devoted to a multidisciplinary study of matter-antimatter asymmetry and, in particular, from the point of view of particle physics, astrophysics and cosmology. A number of topics, such as the practical applications of antimatter in medical imaging, of particular interest to non-specialists, will also be briefly covered. More than thirty years after the discovery of CP violation in the kaon system, precision experiments with kaons at CERN and Fermilab have demonstrated the existence of direct CP violation, opening a window on a hitherto poorly explored part of particle physics. On the one hand, two experiments devoted mainly to CP violation in B mesons, BABAR and Belle, are beginning to test CP violation in the Standard Model in a decisive way. On the other hand, balloon experiments and the space-based AMS project are circumscribing precise limits on the cosmological abundance of antimatter. Finally, the fundamental problem of cosmological matter-antimatter asymmetry at a Grand Unification scale or at the Electroweak phase transition has been the object of intense theoretical activity in recent years. This document gathers most of the slides that have been presented in the plenary and parallel sessions.

  10. Exchange asymmetry in experimental settings

    Science.gov (United States)

    Thomas C. Brown; Mark D. Morrison; Jacob A. Benfield; Gretchen Nurse Rainbolt; Paul A. Bell

    2015-01-01

    We review past trading experiments and present 11 new experiments designed to show how the trading rate responds to alterations of the experimental procedure. In agreement with earlier studies, results show that if the trade decision is converted to one resembling a choice between goods the exchange asymmetry disappears, but otherwise the asymmetry is...

  11. Lepton forward-backward asymmetries

    International Nuclear Information System (INIS)

    Pain, R.

    1992-01-01

    Results of Forward-Backward Asymmetries with Leptons measured at Z 0 energies are presented. Details of the analysis by the DELPHI Collaboration are given together with the most recent values of the peak Asymmetries for electrons, muons and taus obtained by ALEPH, DELPHI, L3 and OPAL Collaborations at LEP

  12. Radiobiology of DNA strand breakage

    International Nuclear Information System (INIS)

    Johansen, I.

    1975-01-01

    The yield of single-strand breaks in lambda DNA within lysogenic host bacteria was measured after exposure to 4-MeV electrons (50 msec) and rapid transfer (45 msec) to alkaline detergent. In nitrogen anoxia the yield was 1.2 x 10 -12 DNA single-strand breaks per rad per dalton, and under full oxygenation the yield increased to 5 x 10 -12 breaks per rad per dalton. A search for the presence of fast repair mechanisms failed to demonstrate the presence of any mechanism for repair of strand breaks operating within a fraction of a second. Strand breaks produced in the presence of oxygen were repaired in 30--40 sec, while breaks produced under anoxia were rejoined even slower. A functional product from the polAl gene was needed for the rejoining of the broken molecules. Intermediate levels of DNA strand breakage seen at low concentrations of oxygen are dependent on the concentration of cellular sulfhydryl compounds, suggesting that in strand breakage oxygen and hydrogen donors compete for reactions with radiation-induced transients in the DNA. Intercomparisons of data on radiation-induced lethality of cells and single-strand breaks in episomal DNA allow the distinction between two classes of radiation-induced radicals, R 1 and R 2 , with different chemical properties; R 1 reacts readily with oxygen and N-oxyls under formation of potentially lethal products. The reactivity of oxygen in this reaction is 30--40 times higher than that of TMPN. R 2 reacts 16 times more readily than R 1 with oxygen under formation of single-strand breaks in the DNA. R 2 does not react with N-oxyls

  13. Measurements of W Charge Asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Holzbauer, J. L. [Mississippi U.

    2015-10-06

    We discuss W boson and lepton charge asymmetry measurements from W decays in the electron channel, which were made using 9.7 fb$^{-1}$ of RunII data collected by the D0 detector at the Fermilab Tevatron Collider. The electron charge asymmetry is presented as a function of pseudo-rapidity out to |$\\eta$| $\\le$ 3.2, in five symmetric and asymmetric kinematic bins of electron transverse momentum and the missing transverse energy of the event. We also give the W charge asymmetry as a function of W boson rapidity. The asymmetries are compared with next-to-leading order perturbative quantum chromodynamics calculations. These charge asymmetry measurements will allow more accurate determinations of the proton parton distribution functions and are the most precise to date.

  14. Asymmetry within social groups

    DEFF Research Database (Denmark)

    Barker, Jessie; Loope, Kevin J.; Reeve, H. Kern

    2016-01-01

    Social animals vary in their ability to compete with group members over shared resources and also vary in their cooperative efforts to produce these resources. Competition among groups can promote within-group cooperation, but many existing models of intergroup cooperation do not explicitly account...... of two roles, with relative competitive efficiency and the number of individuals varying between roles. Players in each role make simultaneous, coevolving decisions. The model predicts that although intergroup competition increases cooperative contributions to group resources by both roles, contributions...... are predominantly from individuals in the less competitively efficient role, whereas individuals in the more competitively efficient role generally gain the larger share of these resources. When asymmetry in relative competitive efficiency is greater, a group's per capita cooperation (averaged across both roles...

  15. Modelling Toehold-Mediated RNA Strand Displacement

    OpenAIRE

    Šulc, Petr; Ouldridge, Thomas E.; Romano, Flavio; Doye, Jonathan P.K.; Louis, Ard A.

    2015-01-01

    We study the thermodynamics and kinetics of an RNA toehold-mediated strand displacement reaction with a recently developed coarse-grained model of RNA. Strand displacement, during which a single strand displaces a different strand previously bound to a complementary substrate strand, is an essential mechanism in active nucleic acid nanotechnology and has also been hypothesized to occur in vivo. We study the rate of displacement reactions as a function of the length of the toehold and temperat...

  16. Fair Exchange in Strand Spaces

    Directory of Open Access Journals (Sweden)

    Joshua D. Guttman

    2009-10-01

    Full Text Available Many cryptographic protocols are intended to coordinate state changes among principals. Exchange protocols coordinate delivery of new values to the participants, e.g. additions to the set of values they possess. An exchange protocol is fair if it ensures that delivery of new values is balanced: If one participant obtains a new possession via the protocol, then all other participants will, too. Fair exchange requires progress assumptions, unlike some other protocol properties. The strand space model is a framework for design and verification of cryptographic protocols. A strand is a local behavior of a single principal in a single session of a protocol. A bundle is a partially ordered global execution built from protocol strands and adversary activities. The strand space model needs two additions for fair exchange protocols. First, we regard the state as a multiset of facts, and we allow strands to cause changes in this state via multiset rewriting. Second, progress assumptions stipulate that some channels are resilient-and guaranteed to deliver messages-and some principals are assumed not to stop at certain critical steps. This method leads to proofs of correctness that cleanly separate protocol properties, such as authentication and confidentiality, from invariants governing state evolution. G. Wang's recent fair exchange protocol illustrates the approach.

  17. Nanocrystal Bioassembly: Asymmetry, Proximity, and Enzymatic Manipulation

    Energy Technology Data Exchange (ETDEWEB)

    Claridge, Shelley A. [Univ. of California, Berkeley, CA (United States)

    2008-05-01

    Research at the interface between biomolecules and inorganic nanocrystals has resulted in a great number of new discoveries. In part this arises from the synergistic duality of the system: biomolecules may act as self-assembly agents for organizing inorganic nanocrystals into functional materials; alternatively, nanocrystals may act as microscopic or spectroscopic labels for elucidating the behavior of complex biomolecular systems. However, success in either of these functions relies heavily uponthe ability to control the conjugation and assembly processes.In the work presented here, we first design a branched DNA scaffold which allows hybridization of DNA-nanocrystal monoconjugates to form discrete assemblies. Importantly, the asymmetry of the branched scaffold allows the formation of asymmetric2assemblies of nanocrystals. In the context of a self-assembled device, this can be considered a step toward the ability to engineer functionally distinct inputs and outputs.Next we develop an anion-exchange high performance liquid chromatography purification method which allows large gold nanocrystals attached to single strands of very short DNA to be purified. When two such complementary conjugates are hybridized, the large nanocrystals are brought into close proximity, allowing their plasmon resonances to couple. Such plasmon-coupled constructs are of interest both as optical interconnects for nanoscale devices and as `plasmon ruler? biomolecular probes.We then present an enzymatic ligation strategy for creating multi-nanoparticle building blocks for self-assembly. In constructing a nanoscale device, such a strategy would allow pre-assembly and purification of components; these constructs can also act as multi-label probes of single-stranded DNA conformational dynamics. Finally we demonstrate a simple proof-of-concept of a nanoparticle analog of the polymerase chain reaction.

  18. Looking for charming asymmetries

    CERN Multimedia

    Stefania Pandolfi

    2016-01-01

    New results presented by the LHCb collaboration on the decay of particles containing a “charm” quark delve deeper into the mystery of matter-antimatter asymmetry.   A view of the LHCb experimental cavern. (Photo: Maximilien Brice/CERN) One of the biggest challenges in physics is to understand why everything we see in our universe seems to be formed only of matter, whereas the Big Bang should have created equal amounts of matter and antimatter. CERN’s LHCb experiment is one of the best hopes for physicists looking to solve this longstanding mystery. At the VIII International Workshop on Charm Physics, which took place in Bologna earlier this month, the LHCb Collaboration presented the most precise measurement to date of a phenomenon called Charge-Parity (CP) violation among particles that contain a charm quark. CP symmetry states that laws of physics are the same if a particle is interchanged with its anti-particle (the “C” part) and if its spatia...

  19. Symmetry and Asymmetry Level Measures

    Directory of Open Access Journals (Sweden)

    Angel Garrido

    2010-04-01

    Full Text Available Usually, Symmetry and Asymmetry are considered as two opposite sides of a coin: an object is either totally symmetric, or totally asymmetric, relative to pattern objects. Intermediate situations of partial symmetry or partial asymmetry are not considered. But this dichotomy on the classification lacks of a necessary and realistic gradation. For this reason, it is convenient to introduce "shade regions", modulating the degree of Symmetry (a fuzzy concept. Here, we will analyze the Asymmetry problem by successive attempts of description and by the introduction of the Asymmetry Level Function, as a new Normal Fuzzy Measure. Our results (both Theorems and Corollaries suppose to be some new and original contributions to such very active and interesting field of research. Previously, we proceed to the analysis of the state of art.

  20. Information Asymmetry and Credit Risk

    Directory of Open Access Journals (Sweden)

    Lorena TUPANGIU

    2017-11-01

    Full Text Available Information asymmetry defines relationships where an agent holds information while another does not hold it. Thus, to the extent that one of the parties to the financing agreement has information more or less accurate than another, the asymmetry of information appears to be a major constraint in the financing of a project. Banks, in their capacity of financial intermediary, operate the transfer of funds to agents in need of financing, to the borrowers, being necessary in this process to have more information in order to benefit of expertise in assessing borrowers. The research of information asymmetry and credit risk consists of interrogating the following aspects: information issues between the bank and borrowers; settlement of information issues; bank’s activism towards information asymmetry. In our approach we will look at the first aspect, namely the information issues between the bank and the borrowers.

  1. Evolution of sexual asymmetry

    Directory of Open Access Journals (Sweden)

    Hoekstra Rolf F

    2004-09-01

    Full Text Available Abstract Background The clear dominance of two-gender sex in recent species is a notorious puzzle of evolutionary theory. It has at least two layers: besides the most fundamental and challenging question why sex exists at all, the other part of the problem is equally perplexing but much less studied. Why do most sexual organisms use a binary mating system? Even if sex confers an evolutionary advantage (through whatever genetic mechanism, why does it manifest that advantage in two, and exactly two, genders (or mating types? Why not just one, and why not more than two? Results Assuming that sex carries an inherent fitness advantage over pure clonal multiplication, we attempt to give a feasible solution to the problem of the evolution of dimorphic sexual asymmetry as opposed to monomorphic symmetry by using a spatial (cellular automaton model and its non-spatial (mean-field approximation. Based on a comparison of the spatial model to the mean-field approximation we suggest that spatial population structure must have played a significant role in the evolution of mating types, due to the largely clonal (self-aggregated spatial distribution of gamete types, which is plausible in aquatic habitats for physical reasons, and appears to facilitate the evolution of a binary mating system. Conclusions Under broad ecological and genetic conditions the cellular automaton predicts selective removal from the population of supposedly primitive gametes that are able to mate with their own type, whereas the non-spatial model admits coexistence of the primitive type and the mating types. Thus we offer a basically ecological solution to a theoretical problem that earlier models based on random gamete encounters had failed to resolve.

  2. Southeast US Historical Marine Mammal Stranding Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data on marine mammal strandings are collected by the Southeast Marine Mammal Stranding Network. Basic data on the location, species identification, animal...

  3. [Presurgical orthodontics for facial asymmetry].

    Science.gov (United States)

    Labarrère, H

    2003-03-01

    As with the treatment of all facial deformities, orthodontic pre-surgical preparation for facial asymmetry should aim at correcting severe occlusal discrepancies not solely on the basis of a narrow occlusal analysis but also in a way that will not disturb the proposed surgical protocol. In addition, facial asymmetries require specific adjustments, difficult to derive and to apply because of their inherent atypical morphological orientation of both alveolar and basal bony support. Three treated cases illustrate different solutions to problems posed by pathological torque: this torque must be considered with respect to proposed surgical changes, within the framework of their limitations and their possible contra-indications.

  4. Complex Odontome Causing Facial Asymmetry

    Directory of Open Access Journals (Sweden)

    Karthikeya Patil

    2006-01-01

    Full Text Available Odontomas are the most common non-cystic odontogenic lesions representing 70% of all odontogenic tumors. Often small and asymptomatic, they are detected on routine radiographs. Occasionally they become large and produce expansion of bone with consequent facial asymmetry. We report a case of such a lesion causing expansion of the mandible in an otherwise asymptomatic patient.

  5. Flavor asymmetry of the nucleon

    International Nuclear Information System (INIS)

    Bijker, R.; Santopinto, E.

    2008-01-01

    The flavor asymmetry of the nucleon sea is discussed in an unquenched quark model for baryons in which the effects of quark-antiquark pairs (uu, dd and ss) are taken into account in an explicit form. The inclusion of qq pairs leads automatically to an excess of d over u quarks in the proton, in agreement with experimental data. (Author)

  6. Flavor asymmetry of the nucleon

    Energy Technology Data Exchange (ETDEWEB)

    Bijker, R. [Instituto de Ciencias Nucleares, UNAM, Apartado Postal 70-543, 04510 Mexico D. F. (Mexico); Santopinto, E. [INFN and Dipartimento di Fisica, Via Dodecaneso 33, I-16146 Genova (Italy)]. e-mail: bijker@nucleares.unam.mx

    2008-12-15

    The flavor asymmetry of the nucleon sea is discussed in an unquenched quark model for baryons in which the effects of quark-antiquark pairs (uu, dd and ss) are taken into account in an explicit form. The inclusion of qq pairs leads automatically to an excess of d over u quarks in the proton, in agreement with experimental data. (Author)

  7. Lambda production and its asymmetry

    International Nuclear Information System (INIS)

    Tatsumi, Daisuke

    1995-01-01

    Differential cross section and asymmetry for Λ 0 , Λ-bar 0 production have been measured in e + e - annihilation at 58 GeV in the scaled momentum Xp range from 0.0 to 0.25. Using 241 pb -1 of data collected after VENUS detector upgrade in 1991. (author)

  8. CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication.

    Science.gov (United States)

    Langston, Lance D; Zhang, Dan; Yurieva, Olga; Georgescu, Roxana E; Finkelstein, Jeff; Yao, Nina Y; Indiani, Chiara; O'Donnell, Mike E

    2014-10-28

    DNA replication in eukaryotes is asymmetric, with separate DNA polymerases (Pol) dedicated to bulk synthesis of the leading and lagging strands. Pol α/primase initiates primers on both strands that are extended by Pol ε on the leading strand and by Pol δ on the lagging strand. The CMG (Cdc45-MCM-GINS) helicase surrounds the leading strand and is proposed to recruit Pol ε for leading-strand synthesis, but to date a direct interaction between CMG and Pol ε has not been demonstrated. While purifying CMG helicase overexpressed in yeast, we detected a functional complex between CMG and native Pol ε. Using pure CMG and Pol ε, we reconstituted a stable 15-subunit CMG-Pol ε complex and showed that it is a functional polymerase-helicase on a model replication fork in vitro. On its own, the Pol2 catalytic subunit of Pol ε is inefficient in CMG-dependent replication, but addition of the Dpb2 protein subunit of Pol ε, known to bind the Psf1 protein subunit of CMG, allows stable synthesis with CMG. Dpb2 does not affect Pol δ function with CMG, and thus we propose that the connection between Dpb2 and CMG helps to stabilize Pol ε on the leading strand as part of a 15-subunit leading-strand holoenzyme we refer to as CMGE. Direct binding between Pol ε and CMG provides an explanation for specific targeting of Pol ε to the leading strand and provides clear mechanistic evidence for how strand asymmetry is maintained in eukaryotes.

  9. Asymmetry quantization and application to human mandibles

    DEFF Research Database (Denmark)

    Glerup, Nanna; Nielsen, Mads; Sporring, Jon

    2004-01-01

    of asymmetry, the statistics on asymmetry for normal and pathological anatomical structures can be compared. Symmetry is a well-known mathematical group theoretical concept. In this paper, we will mathematically define the concept of weak symmetry, including topological symmetry, which serves as a basis...... of pathological assumed non-symmetric mandibles exhibiting a statistically significant increase of asymmetry....

  10. Asymmetry and coherence weight of quantum states

    Science.gov (United States)

    Bu, Kaifeng; Anand, Namit; Singh, Uttam

    2018-03-01

    The asymmetry of quantum states is an important resource in quantum information processing tasks such as quantum metrology and quantum communication. In this paper, we introduce the notion of asymmetry weight—an operationally motivated asymmetry quantifier in the resource theory of asymmetry. We study the convexity and monotonicity properties of asymmetry weight and focus on its interplay with the corresponding semidefinite programming (SDP) forms along with its connection to other asymmetry measures. Since the SDP form of asymmetry weight is closely related to asymmetry witnesses, we find that the asymmetry weight can be regarded as a (state-dependent) asymmetry witness. Moreover, some specific entanglement witnesses can be viewed as a special case of an asymmetry witness—which indicates a potential connection between asymmetry and entanglement. We also provide an operationally meaningful coherence measure, which we term coherence weight, and investigate its relationship to other coherence measures like the robustness of coherence and the l1 norm of coherence. In particular, we show that for Werner states in any dimension d all three coherence quantifiers, namely, the coherence weight, the robustness of coherence, and the l1 norm of coherence, are equal and are given by a single letter formula.

  11. Geometric asymmetry driven Janus micromotors

    Science.gov (United States)

    Zhao, Guanjia; Pumera, Martin

    2014-09-01

    The production and application of nano-/micromotors is of great importance. In order for the motors to work, asymmetry in their chemical composition or physical geometry must be present if no external asymmetric field is applied. In this paper, we present a ``coconut'' micromotor made of platinum through the partial or complete etching of the silica templates. It was shown that although both the inner and outer surfaces are made of the same material (Pt), motion of the structure can be observed as the convex surface is capable of generating oxygen bubbles. This finding shows that not only the chemical asymmetry of the micromotor, but also its geometric asymmetry can lead to fast propulsion of the motor. Moreover, a considerably higher velocity can be seen for partially etched coconut structures than the velocities of Janus or fully etched, shell-like motors. These findings will have great importance on the design of future micromotors.The production and application of nano-/micromotors is of great importance. In order for the motors to work, asymmetry in their chemical composition or physical geometry must be present if no external asymmetric field is applied. In this paper, we present a ``coconut'' micromotor made of platinum through the partial or complete etching of the silica templates. It was shown that although both the inner and outer surfaces are made of the same material (Pt), motion of the structure can be observed as the convex surface is capable of generating oxygen bubbles. This finding shows that not only the chemical asymmetry of the micromotor, but also its geometric asymmetry can lead to fast propulsion of the motor. Moreover, a considerably higher velocity can be seen for partially etched coconut structures than the velocities of Janus or fully etched, shell-like motors. These findings will have great importance on the design of future micromotors. Electronic supplementary information (ESI) available: Additional SEM images, data analysis, Videos S

  12. Knowledge asymmetries about product "goodness"

    DEFF Research Database (Denmark)

    Kampf, Constance

    and actions towards workers, and findings of independent researchers.  Currently, differing perspectives on product "goodness" are being addressed and mediated by NGOs and B-corporations, as they work with private companies and corporations to communicate product information to consumers.  One organization...... focused on scenarios where shoppers were asked about CSR in their product decisions found that: "...when consumers are given information that they trust about a company's level of social responsibility, it affects how they evaluate the company and their purchase intentions. Furthermore, a low price did.......  Asymmetries in knowledge about product "goodness" make it difficult for ethically inspired consumers to make informed decisions about the products they purchase.  These knowledge asymmetries emerge from differing perspectives on guidelines for consumer safety set by government bodies, CSR initiatives...

  13. Perceptual asymmetry in texture perception.

    Science.gov (United States)

    Williams, D; Julesz, B

    1992-07-15

    A fundamental property of human visual perception is our ability to distinguish between textures. A concerted effort has been made to account for texture segregation in terms of linear spatial filter models and their nonlinear extensions. However, for certain texture pairs the ease of discrimination changes when the role of figure and ground are reversed. This asymmetry poses a problem for both linear and nonlinear models. We have isolated a property of texture perception that can account for this asymmetry in discrimination: subjective closure. This property, which is also responsible for visual illusions, appears to be explainable by early visual processes alone. Our results force a reexamination of the process of human texture segregation and of some recent models that were introduced to explain it.

  14. Audiometric asymmetry and tinnitus laterality.

    Science.gov (United States)

    Tsai, Betty S; Sweetow, Robert W; Cheung, Steven W

    2012-05-01

    To identify an optimal audiometric asymmetry index for predicting tinnitus laterality. Retrospective medical record review. Data from adult tinnitus patients (80 men and 44 women) were extracted for demographic, audiometric, tinnitus laterality, and related information. The main measures were sensitivity, specificity, positive predictive value (PPV), and receiver operating characteristic (ROC) curves. Three audiometric asymmetry indices were constructed using one, two, or three frequency elements to compute the average interaural threshold difference (aITD). Tinnitus laterality predictive performance of a particular index was assessed by increasing the cutoff or minimum magnitude of the aITD from 10 to 35 dB in 5-dB steps to determine its ROC curve. Single frequency index performance was inferior to the other two (P .05). Two adjoining frequency elements with aITD ≥ 15 dB performed optimally for predicting tinnitus laterality (sensitivity = 0.59, specificity = 0.71, and PPV = 0.76). Absolute and relative magnitudes of hearing loss in the poorer ear were uncorrelated with tinnitus distress. An optimal audiometric asymmetry index to predict tinnitus laterality is one whereby 15 dB is the minimum aITD of two adjoining frequencies, inclusive of the maximal ITD. Tinnitus laterality dependency on magnitude of interaural asymmetry may inform design and interpretation of neuroimaging studies. Monaural acoustic tinnitus therapy may be an initial consideration for asymmetric hearing loss meeting the criterion of aITD ≥ 15 dB. Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.

  15. Asymmetry Reduction Theory of FDI

    DEFF Research Database (Denmark)

    Li, Xin

    In this paper, I first briefly introduce Moon & Roehl’s (1993, 2001) imbalance theory of FDI, then I identify its three deficiencies that may be responsible for the relative lack of impact of the potentially powerful imbalance logic, and then I propose an asymmetry reduction theory (ARC) of FDI...... and explain its aspiration-resource-control (ARC) framework. I conclude the paper with a brief discussion of the OLI framework being a special case of the ARC framework....

  16. Perceptual asymmetry in texture perception.

    OpenAIRE

    Williams, D; Julesz, B

    1992-01-01

    A fundamental property of human visual perception is our ability to distinguish between textures. A concerted effort has been made to account for texture segregation in terms of linear spatial filter models and their nonlinear extensions. However, for certain texture pairs the ease of discrimination changes when the role of figure and ground are reversed. This asymmetry poses a problem for both linear and nonlinear models. We have isolated a property of texture perception that can account for...

  17. Investor relations and information asymmetry

    Directory of Open Access Journals (Sweden)

    Sandrielem da Silva Rodrigues

    2017-03-01

    Full Text Available ABSTRACT Companies invest significant volumes of resources in investor relations (IR departments. The professionals working in the IR department are responsible for communication between the company and the market, so that the information generated is widely disseminated and understood by investors. In this context, this research aims to investigate whether there is evidence that the IR activity decreases information asymmetry between the company and the market. Specifically, we evaluate the hypothesis that Brazilian companies with IR websites classified as more informative have a reduced bid-ask spread (proxy for asymmetry. Therefore, this paper classifies the informative content from IR websites of Brazilian companies for the years 2013 and 2014 and relates the outcomes obtained with information asymmetry metrics. Initially, the estimation considers the pooled ordinary least squares (POLS model and, at a second moment, in order to mitigate potential endogeneity problems, the pooled two-stage least squares (2SLS model is used. The results indicate that more informative IR websites are able to decrease the bid-ask spread of Brazilian listed companies. This finding strongly encourages companies to provide information to stakeholders on well-structured IR websites of their own.

  18. INFORMATION ASYMMETRY AND HERDING BEHAVIOR

    Directory of Open Access Journals (Sweden)

    Puput Tri Komalasari

    2016-06-01

    Full Text Available Conceptually, the stock market is strong form efficient in the long term. However, in practice, there are various forms of market anomalies that undermine the accuracy of the efficient market hypothesis. One factor suspected as the cause of market inefficiency is herding behavior. Investors herd when they imitate the actions of other investors. This behavior occurs when there is a continuous interaction among rational investors that prevents them from seeking information about market fundamentals. This study provides new insights by including information asymmetry as a moderating variable. This research examines the phenomenon of herding behavior in the Indonesia Stock Exchange as well as examines directly the effect of information asymmetry on herding behavior. The period of study is 2008 using time series of daily stocks data that actively traded in the capital market. Results of this study find that investor tends to follow market consensus when price changes at the low level, but when there is large price swing market participant acts independently from other investors. Interestingly, this study finds that information asymmetry is a necessary condition for the existence of herding behavior.

  19. A 3'-end structure in RNA2 of a crinivirus is essential for viral RNA synthesis and contributes to replication-associated translation activity.

    Science.gov (United States)

    Mongkolsiriwattana, Chawin; Zhou, Jaclyn S; Ng, James C K

    2016-10-03

    The terminal ends in the genome of RNA viruses contain features that regulate viral replication and/or translation. We have identified a Y-shaped structure (YSS) in the 3' terminal regions of the bipartite genome of Lettuce chlorosis virus (LCV), a member in the genus Crinivirus (family Closteroviridae). The YSS is the first in this family of viruses to be determined using Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension (SHAPE). Using luciferase constructs/replicons, in vivo and in vitro assays showed that the 5' and YSS-containing 3' terminal regions of LCV RNA1 supported translation activity. In contrast, similar regions from LCV RNA2, including those upstream of the YSS, did not. LCV RNA2 mutants with nucleotide deletions or replacements that affected the YSS were replication deficient. In addition, the YSS of LCV RNA1 and RNA2 were interchangeable without affecting viral RNA synthesis. Translation and significant replication were observed for specific LCV RNA2 replicons only in the presence of LCV RNA1, but both processes were impaired when the YSS and/or its upstream region were incomplete or altered. These results are evidence that the YSS is essential to the viral replication machinery, and contributes to replication enhancement and replication-associated translation activity in the RNA2 replicons.

  20. [Diagnosis of facial and craniofacial asymmetry].

    Science.gov (United States)

    Arnaud, E; Marchac, D; Renier, D

    2001-10-01

    Craniofacial asymmetry is caused by various aetiologies but clinical examination remains the most important criteria since minor asymmetry is always present. The diagnosis can be confirmed by anthropometric measurements and radiological examinations but only severe asymmetries or asymmetries with an associated functional impairment should be treated. The treatment depends on the cause, and on the time of appearance. Congenital asymmetries might be treated early, during the first year of life if a craniosynostosis is present. Hemifacial microsomia are treated later if there is no breathing impairment. Since the pediatricians have recommended the dorsal position for infant sleeping, an increasing number of posterior flattening of the skull has been appearing, and could be prevented by adequate nursing. Other causes of craniofacial asymmetries are rare and should be adapted to the cause (tumors, atrophies, neurological paralysis, hypertrophies) by a specialized multidisciplinar team.

  1. Modelling toehold-mediated RNA strand displacement.

    Science.gov (United States)

    Šulc, Petr; Ouldridge, Thomas E; Romano, Flavio; Doye, Jonathan P K; Louis, Ard A

    2015-03-10

    We study the thermodynamics and kinetics of an RNA toehold-mediated strand displacement reaction with a recently developed coarse-grained model of RNA. Strand displacement, during which a single strand displaces a different strand previously bound to a complementary substrate strand, is an essential mechanism in active nucleic acid nanotechnology and has also been hypothesized to occur in vivo. We study the rate of displacement reactions as a function of the length of the toehold and temperature and make two experimentally testable predictions: that the displacement is faster if the toehold is placed at the 5' end of the substrate; and that the displacement slows down with increasing temperature for longer toeholds. Copyright © 2015 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  2. Aggression and Brain Asymmetries: A Theoretical Review

    OpenAIRE

    Rohlfs , Paloma; Ramirez, J. Martin

    2006-01-01

    The relationship between aggression and brain asymmetries has not been studied enough. The association between both concepts can be approached from two different perspectives. One perspective points to brain asymmetries underlying the emotion of anger and consequently aggression in normal people. Another one is concerned with the existence of brain asymmetries in aggressive people (e.g., in the case of suicides or psychopathies). Research on emotional processing points out the confusion betw...

  3. Structural Connectivity Asymmetry in the Neonatal Brain

    OpenAIRE

    Ratnarajah, Nagulan; Rifkin-Graboi, Anne; Fortier, Marielle V.; Chong, Yap Seng; Kwek, Kenneth; Saw, Seang-Mei; Godfrey, Keith M; Gluckman, Peter D.; Meaney, Michael J.; Qiu, Anqi

    2013-01-01

    Asymmetry of the neonatal brain is not yet understood at the level of structural connectivity. We utilized DTI deterministic tractography and structural network analysis based on graph theory to determine the pattern of structural connectivity asymmetry in 124 normal neonates. We tracted white matter axonal pathways characterizing interregional connections among brain regions and inferred asymmetry in left and right anatomical network properties. Our findings revealed that in neonates, small-...

  4. Breast asymmetry and predisposition to breast cancer

    OpenAIRE

    Scutt, Diane; Lancaster, Gillian A; Manning, John T

    2006-01-01

    INTRODUCTION: It has been shown in our previous work that breast asymmetry is related to several of the known risk factors for breast cancer, and that patients with diagnosed breast cancer have more breast volume asymmetry, as measured from mammograms, than age-matched healthy women. METHODS: In the present study, we compared the breast asymmetry of women who were free of breast disease at time of mammography, but who had subsequently developed breast cancer, with that of age-matched healthy ...

  5. Asymmetry a challenge for orthodontists

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    planes of space. A systematic approach to the identification of the cause of the asymmetry head precede the decision whether to correct or to camouflage. The definition of a specific treatment goal should be done only following an analysis of the likelihood that the force system necessary to perform...... the required tooth displacements can be generated. In order to control the interaction between the force systems developed in the three planes of space, the appliances should commonly be segmented. Anchorage problems can occasionally only be solved by means of skeletal anchorage....

  6. Fluctuating Asymmetry of Human Populations: A Review

    Directory of Open Access Journals (Sweden)

    John H. Graham

    2016-12-01

    Full Text Available Fluctuating asymmetry, the random deviation from perfect symmetry, is a widely used population-level index of developmental instability, developmental noise, and robustness. It reflects a population’s state of adaptation and genomic coadaptation. Here, we review the literature on fluctuating asymmetry of human populations. The most widely used bilateral traits include skeletal, dental, and facial dimensions; dermatoglyphic patterns and ridge counts; and facial shape. Each trait has its advantages and disadvantages, but results are most robust when multiple traits are combined into a composite index of fluctuating asymmetry (CFA. Both environmental (diet, climate, toxins and genetic (aneuploidy, heterozygosity, inbreeding stressors have been linked to population-level variation in fluctuating asymmetry. In general, these stressors increase average fluctuating asymmetry. Nevertheless, there have been many conflicting results, in part because (1 fluctuating asymmetry is a weak signal in a sea of noise; and (2 studies of human fluctuating asymmetry have not always followed best practices. The most serious concerns are insensitive asymmetry indices (correlation coefficient and coefficient of indetermination, inappropriate size scaling, unrecognized mixture distributions, inappropriate corrections for directional asymmetry, failure to use composite indices, and inattention to measurement error. Consequently, it is often difficult (or impossible to compare results across traits, and across studies.

  7. Parity violating asymmetries in polarized electron scattering

    International Nuclear Information System (INIS)

    Derman, E.; Marciano, W.J.

    1979-01-01

    We discuss parity violating asymmetries between the scattering of right and left-handed electrons on a variety of targets. Implications for gauge theories from recent SLAC results on deep-inelastic electron-deuterium and electron-proton scattering are examined. A derivation of the asymmetry for electron-electron scattering is given, its advantages are pointed out, and the feasibility of such a measurement is discussed. Other proposed or contemplated asymmetry experiments are reviewed and the necessity of including the Collins-Wilczek-Zee hadronic axial isoscalar current contribution in asymmetry predictions is noted

  8. Single spin asymmetry for charm mesons

    Energy Technology Data Exchange (ETDEWEB)

    Dominguez Zacarias, G. [PIMAyC, Eje Central Lazaro Cardenas No. 152, Apdo. Postal 14-805, D.F. (Mexico); Herrera, G.; Mercado, J. [Centro de Investigacion y de Estudios Avanzados, Apdo. Postal 14-740, D.F. (Mexico)

    2007-08-15

    We study single spin asymmetries of D{sup 0} and D{sup -} mesons in polarized proton-proton collisions. A two component model is used to describe charm meson production. The production of D mesons occurs by recombination of the constituents present in the initial state as well as by fragmentation of quarks in the final state. This model has proved to describe the production of charm. The recombination component involves a mechanism of spin alignment that ends up in a single spin asymmetry. Experimental measurements of single spin asymmetry for pions at RHIC are compared with the model. Predictions for the asymmetry in D mesons are presented. (orig.)

  9. Single spin asymmetry for charm mesons

    International Nuclear Information System (INIS)

    Dominguez Zacarias, G.; Herrera, G.; Mercado, J.

    2007-01-01

    We study single spin asymmetries of D 0 and D - mesons in polarized proton-proton collisions. A two component model is used to describe charm meson production. The production of D mesons occurs by recombination of the constituents present in the initial state as well as by fragmentation of quarks in the final state. This model has proved to describe the production of charm. The recombination component involves a mechanism of spin alignment that ends up in a single spin asymmetry. Experimental measurements of single spin asymmetry for pions at RHIC are compared with the model. Predictions for the asymmetry in D mesons are presented. (orig.)

  10. The stranding anomaly as population indicator

    DEFF Research Database (Denmark)

    Peltier, Helene; Baagøe, Hans J.; Camphuysen, Kees C. J.

    2013-01-01

    Ecological indicators for monitoring strategies are expected to combine three major characteristics: ecological significance, statistical credibility, and cost-effectiveness. Strategies based on stranding networks rank highly in cost-effectiveness, but their ecological significance and statistica...... surveys, mostly SCANS surveys (1994 and 2005). This new indicator could be applied to cetacean populations across the world and more widely to marine megafauna....... credibility are disputed. Our present goal is to improve the value of stranding data as population indicator as part of monitoring strategies by constructing the spatial and temporal null hypothesis for strandings. The null hypothesis is defined as: small cetacean distribution and mortality are uniform...

  11. Strand Displacement by DNA Polymerase III Occurs through a τ-ψ-χ Link to Single-stranded DNA-binding Protein Coating the Lagging Strand Template*

    OpenAIRE

    Yuan, Quan; McHenry, Charles S.

    2009-01-01

    In addition to the well characterized processive replication reaction catalyzed by the DNA polymerase III holoenzyme on single-stranded DNA templates, the enzyme possesses an intrinsic strand displacement activity on flapped templates. The strand displacement activity is distinguished from the single-stranded DNA-templated reaction by a high dependence upon single-stranded DNA binding protein and an inability of γ-complex to support the reaction in the absence of τ. However, if γ-complex is p...

  12. On the Compton Twist-3 Asymmetries

    International Nuclear Information System (INIS)

    Korotkiyan, V.M.; Teryaev, O.V.

    1994-01-01

    The 'fermionic poles' contribution to the twist-3 single asymmetry in the gluon Compton process is calculated. The 'gluonic poles' existence seems to contradict the density matrix positivity. Qualitative predictions for the direct photon and jets asymmetries are presented. 13 refs., 2 figs

  13. Multiple photon emission and b quark asymmetries

    International Nuclear Information System (INIS)

    Jadach, S.; Ward, B.F.L.

    1989-08-01

    We discuss the effects of multiple photon final states in high precision tests of the SU 2L x U 1 model wherein one measures the b quark asymmetries at a very high luminosity Z 0 factory, such as the possible high luminosity upgrade of the CERN LEP collider. The specific asymmetries analyzed are the forward-backward asymmetry A FB , the left-right polarized asymmetry A LR and the polarized forward-backward asymmetry A FB,pol. . The radiative effects are found to be significant for A FB as expected, but they are not as large, on a percentage basis, as the corresponding result for muons. (author). 5 refs, 1 tab

  14. Toroidal current asymmetry in tokamak disruptions

    Science.gov (United States)

    Strauss, H. R.

    2014-10-01

    It was discovered on JET that disruptions were accompanied by toroidal asymmetry of the toroidal plasma current I ϕ. It was found that the toroidal current asymmetry was proportional to the vertical current moment asymmetry with positive sign for an upward vertical displacement event (VDE) and negative sign for a downward VDE. It was observed that greater displacement leads to greater measured I ϕ asymmetry. Here, it is shown that this is essentially a kinematic effect produced by a VDE interacting with three dimensional MHD perturbations. The relation of toroidal current asymmetry and vertical current moment is calculated analytically and is verified by numerical simulations. It is shown analytically that the toroidal variation of the toroidal plasma current is accompanied by an equal and opposite variation of the toroidal current flowing in a thin wall surrounding the plasma. These currents are connected by 3D halo current, which is π/2 radians out of phase with the n = 1 toroidal current variations.

  15. Separate base usages of genes located on the leading and lagging strands in Chlamydia muridarum revealed by the Z curve method

    Directory of Open Access Journals (Sweden)

    Yu Xiu-Juan

    2007-10-01

    Full Text Available Abstract Background The nucleotide compositional asymmetry between the leading and lagging strands in bacterial genomes has been the subject of intensive study in the past few years. It is interesting to mention that almost all bacterial genomes exhibit the same kind of base asymmetry. This work aims to investigate the strand biases in Chlamydia muridarum genome and show the potential of the Z curve method for quantitatively differentiating genes on the leading and lagging strands. Results The occurrence frequencies of bases of protein-coding genes in C. muridarum genome were analyzed by the Z curve method. It was found that genes located on the two strands of replication have distinct base usages in C. muridarum genome. According to their positions in the 9-D space spanned by the variables u1 – u9 of the Z curve method, K-means clustering algorithm can assign about 94% of genes to the correct strands, which is a few percent higher than those correctly classified by K-means based on the RSCU. The base usage and codon usage analyses show that genes on the leading strand have more G than C and more T than A, particularly at the third codon position. For genes on the lagging strand the biases is reverse. The y component of the Z curves for the complete chromosome sequences show that the excess of G over C and T over A are more remarkable in C. muridarum genome than in other bacterial genomes without separating base and/or codon usages. Furthermore, for the genomes of Borrelia burgdorferi, Treponema pallidum, Chlamydia muridarum and Chlamydia trachomatis, in which distinct base and/or codon usages have been observed, closer phylogenetic distance is found compared with other bacterial genomes. Conclusion The nature of the strand biases of base composition in C. muridarum is similar to that in most other bacterial genomes. However, the base composition asymmetry between the leading and lagging strands in C. muridarum is more significant than that in

  16. Asymmetry effects in fragment production

    Energy Technology Data Exchange (ETDEWEB)

    Kaur, Manpreet [Sri Guru Granth Sahib World University, Fatehgarh Sahib-140406, Punjab (India); Kaur, Varinderjit, E-mail: drvarinderjit@gmail.com [Mata Gujri College, Fatehgarh Sahib-140406, Punjab (India)

    2016-05-06

    The production of different fragments has been studied by taking into account the mass asymmetry of the reaction and employing the momentum dependent interactions. Two different set of asymmetric reactions have been analyzed while keeping At{sub otal} fixed using soft momentum dependent equation of state. Our results indicate that the impact of momentum dependent interactions is different in lighter projectile systems as compared to heavier ones. The comparative analysis of IQMD simulations with the experimental data in case of heavier projectile and lighter target system for the reaction of {sup 197}Au+{sup 27}Al (η = 0.7) at E = 600 MeV/nucleon shows that with the inclusion of MDI we are able, upto some extent, to reproduce the experimental universality of rise and fall of intermediate mass fragments (IMFs).

  17. Bs semileptonic asymmetry at LHCb

    CERN Multimedia

    Dufour, Laurent

    2016-01-01

    When neutral $B^{0}_{s,d}$ mesons evolve in time they can change into their own antiparticles. In this mixing process CP symmetry is not necessarily conserved, as the probability for a $B^{0}$ meson to change into a $\\bar{B}^{0}$ meson can be different from the probability for the reverse process. The CP violation in the $B^{0}_{s}$ system as measured using semileptonic decays, defined as $a^{s}_{sl}$, is very small according to the Standard Model. However, earlier measurements of the semileptonic mixing asymmetry in both the $B_s^{0}$ and $B_d^{0}$ systems have shown a $3 \\sigma$ deviation with respect to the Standard Model value. A measurement of $a^{s}_{sl}$ performed using $1 \\text{fb}^{-1}$ of data collected at the LHCb detector is presented, together with an outlook to the updated $3 \\text{fb}^{-1}$ result.

  18. The (not so) Immortal Strand Hypothesis

    OpenAIRE

    Tomasetti, Cristian; Bozic, Ivana

    2015-01-01

    Background: Non-random segregation of DNA strands during stem cell replication has been proposed as a mechanism to minimize accumulated genetic errors in stem cells of rapidly dividing tissues. According to this hypothesis, an “immortal” DNA strand is passed to the stem cell daughter and not the more differentiated cell, keeping the stem cell lineage replication error-free. After it was introduced, experimental evidence both in favor and against the hypothesis has been presented. Principal...

  19. Spectral asymmetry for bag boundary conditions

    International Nuclear Information System (INIS)

    Beneventano, C G; Santangelo, E M; Wipf, A

    2002-01-01

    We give an expression, in terms of boundary spectral functions, for the spectral asymmetry of the Euclidean Dirac operator in two dimensions, when its domain is determined by local boundary conditions and the manifold is of product type. As an application, we explicitly evaluate the asymmetry in the case of a finite-length cylinder and check that the outcome is consistent with our general result. Finally, we study the asymmetry in a disc, which is a non-product case, and propose an interpretation

  20. Witnessing Multipartite Entanglement by Detecting Asymmetry

    Directory of Open Access Journals (Sweden)

    Davide Girolami

    2017-03-01

    Full Text Available The characterization of quantum coherence in the context of quantum information theory and its interplay with quantum correlations is currently subject of intense study. Coherence in a Hamiltonian eigenbasis yields asymmetry, the ability of a quantum system to break a dynamical symmetry generated by the Hamiltonian. We here propose an experimental strategy to witness multipartite entanglement in many-body systems by evaluating the asymmetry with respect to an additive Hamiltonian. We test our scheme by simulating asymmetry and entanglement detection in a three-qubit Greenberger–Horne–Zeilinger (GHZ diagonal state.

  1. Mechanical properties of rubberwood oriented strand lumber (OSL: The effect of strand length

    Directory of Open Access Journals (Sweden)

    Buhnnum Kyokong

    2005-09-01

    Full Text Available Effect of strand length on mechanical properties (tension, compression and bending of oriented strand lumber (OSL made of rubberwood (Hevea brasiliensis Muell. Arg. was reported. Three strand lengths of 50 mm, 100 mm, and 150 mm with 1 mm thickness and 15 mm width were used. The strands were mixed with 5% pMDI glue (weight basis in a tumble mixer. The OSL specimens were formed by hot pressing process of unidirectionally aligned strands. Average specific gravity and moisture content were 0.76 and 8.34%, respectively. Tension and compression tests were carried out for directions both parallel and perpendicular to grain while bending test was performed only in parallel direction. Ultimate stresses and moduli of elasticity were examined from the stress-strain curves. It was found that for the parallel-to-grain direction, the longer strand OSL gave higher strength. The role of the strand length did not appear for the direction normal to the grain. The relationship between the mechanical properties of OSL and strand length was well described by the modified Hankinson formula.

  2. Experimental investigation of transverse spin asymmetries in muon-p SIDIS processes: Sivers asymmetries

    CERN Document Server

    Adolph, C.; Alexakhin, V.Yu.; Alexandrov, Yu.; Alexeev, G.D.; Amoroso, A.; Antonov, A.A.; Austregesilo, A.; Badelek, B.; Balestra, F.; Barth, J.; Baum, G.; Bedfer, Y.; Bernhard, J.; Bertini, R.; Bettinelli, M.; Bicker, K.; Bieling, J.; Birsa, R.; Bisplinghoff, J.; Bordalo, P.; Bradamante, F.; Braun, C.; Bravar, A.; Bressan, A.; Burtin, E.; Capozza, L.; Chiosso, M.; Chung, S.U.; Cicuttin, A.; Crespo, M.L.; Dalla Torre, S.; Das, S.; Dasgupta, S.S.; Dasgupta, S.; Denisov, O.Yu.; Dhara, L.; Donskov, S.V.; Doshita, N.; Duic, V.; Dunnweber, W.; Dziewiecki, M.; Efremov, A.; Elia, C.; Eversheim, P.D.; Eyrich, W.; Faessler, M.; Ferrero, A.; Filin, A.; Finger, M.; Fischer, H.; Franco, C.; von Hohenesche, N.du Fresne; Friedrich, J.M.; Frolov, V.; Garfagnini, R.; Gautheron, F.; Gavrichtchouk, O.P.; Gerassimov, S.; Geyer, R.; Giorgi, M.; Gnesi, I.; Gobbo, B.; Goertz, S.; Grabmuller, S.; Grasso, A.; Grube, B.; Gushterski, R.; Guskov, A.; Guthorl, T.; Haas, F.; von Harrach, D.; Heinsius, F.H.; Herrmann, F.; Hess, C.; Hinterberger, F.; Horikawa, N.; Hoppner, Ch.; d'Hose, N.; Ishimoto, S.; Ivanov, O.; Ivanshin, Yu.; Iwata, T.; Jahn, R.; Jary, V.; Jasinski, P.; Joosten, R.; Kabuss, E.; Kang, D.; Ketzer, B.; Khaustov, G.V.; Khokhlov, Yu.A.; Kisselev, Yu.; Klein, F.; Klimaszewski, K.; Koblitz, S.; Koivuniemi, J.H.; Kolosov, V.N.; Kondo, K.; Konigsmann, K.; Konorov, I.; Konstantinov, V.F.; Korzenev, A.; Kotzinian, A.M.; Kouznetsov, O.; Kramer, M.; Kroumchtein, Z.V.; Kunne, F.; Kurek, K.; Lauser, L.; Lednev, A.A.; Lehmann, A.; Levorato, S.; Lichtenstadt, J.; Liska, T.; Maggiora, A.; Magnon, A.; Makke, N.; Mallot, G.K.; Mann, A.; Marchand, C.; Martin, A.; Marzec, J.; Matsuda, T.; Meshcheryakov, G.; Meyer, W.; Michigami, T.; Mikhailov, Yu.V.; Moinester, M.A.; Morreale, A.; Mutter, A.; Nagaytsev, A.; Nagel, T.; Negrini, T.; Nerling, F.; Neubert, S.; Neyret, D.; Nikolaenko, V.I.; Nowak, W.D.; Nunes, A.S.; Olshevsky, A.G.; Ostrick, M.; Padee, A.; Panknin, R.; Panzieri, D.; Parsamyan, B.; Paul, S.; Perevalova, E.; Pesaro, G.; Peshekhonov, D.V.; Piragino, G.; Platchkov, S.; Pochodzalla, J.; Polak, J.; Polyakov, V.A.; Pretz, J.; Quaresma, M.; Quintans, C.; Rajotte, J.F.; Ramos, S.; Rapatsky, V.; Reicherz, G.; Richter, A.; Rocco, E.; Rondio, E.; Rossiyskaya, N.S.; Ryabchikov, D.I.; Samoylenko, V.D.; Sandacz, A.; Sapozhnikov, M.G.; Sarkar, S.; Savin, I.A.; Sbrizzai, G.; Schiavon, P.; Schill, C.; Schluter, T.; Schmidt, K.; Schmitt, L.; Schonning, K.; Schopferer, S.; Schott, M.; Schroder, W.; Shevchenko, O.Yu.; Silva, L.; Sinha, L.; Sissakian, A.N.; Slunecka, M.; Smirnov, G.I.; Sosio, S.; Sozzi, F.; Srnka, A.; Steiger, L.; Stolarski, M.; Sulc, M.; Sulej, R.; Suzuki, H.; Sznajder, P.; Takekawa, S.; Wolbeek, J.Ter; Tessaro, S.; Tessarotto, F.; Tkatchev, L.G.; Uhl, S.; Uman, I.; Vandenbroucke, M.; Virius, M.; Vlassov, N.V.; Wang, L.; Wilfert, M.; Windmolders, R.; Wislicki, W.; Wollny, H.; Zaremba, K.; Zavertyaev, M.; Zemlyanichkina, E.; Ziembicki, M.; Zhuravlev, N.; Zvyagin, A.

    2012-10-31

    The COMPASS Collaboration at CERN has measured the transverse spin azimuthal asymmetry of charged hadrons produced in semi-inclusive deep inelastic scattering using a 160 GeV positive muon beam and a transversely polarised NH_3 target. The Sivers asymmetry of the proton has been extracted in the Bjorken x range 0.003 0.03. The asymmetry is different from zero and positive also in the low x region, where sea-quarks dominate. The kinematic dependence of the asymmetry has also been investigated and results are given for various intervals of hadron and virtual photon fractional energy. In contrast to the case of the Collins asymmetry, the results on the Sivers asymmetry suggest a strong dependence on the four-momentum transfer to the nucleon, in agreement with the most recent calculations.

  3. Leptogenesis and gravity: Baryon asymmetry without decays

    Directory of Open Access Journals (Sweden)

    J.I. McDonald

    2017-03-01

    Full Text Available A popular class of theories attributes the matter-antimatter asymmetry of the Universe to CP-violating decays of super-heavy BSM particles in the Early Universe. Recently, we discovered a new source of leptogenesis in these models, namely that the same Yukawa phases which provide the CP violation for decays, combined with curved-spacetime loop effects, lead to an entirely new gravitational mechanism for generating an asymmetry, driven by the expansion of the Universe and independent of the departure of the heavy particles from equilibrium. In this Letter, we build on previous work by analysing the full Boltzmann equation, exploring the full parameter space of the theory and studying the time-evolution of the asymmetry. Remarkably, we find regions of parameter space where decays play no part at all, and where the baryon asymmetry of the Universe is determined solely by gravitational effects.

  4. Leptogenesis and gravity: Baryon asymmetry without decays

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, J.I., E-mail: pymcdonald@swansea.ac.uk; Shore, G.M., E-mail: g.m.shore@swansea.ac.uk

    2017-03-10

    A popular class of theories attributes the matter-antimatter asymmetry of the Universe to CP-violating decays of super-heavy BSM particles in the Early Universe. Recently, we discovered a new source of leptogenesis in these models, namely that the same Yukawa phases which provide the CP violation for decays, combined with curved-spacetime loop effects, lead to an entirely new gravitational mechanism for generating an asymmetry, driven by the expansion of the Universe and independent of the departure of the heavy particles from equilibrium. In this Letter, we build on previous work by analysing the full Boltzmann equation, exploring the full parameter space of the theory and studying the time-evolution of the asymmetry. Remarkably, we find regions of parameter space where decays play no part at all, and where the baryon asymmetry of the Universe is determined solely by gravitational effects.

  5. Do Board Characteristics Affect Information Asymmetry?

    OpenAIRE

    Sougné, Danielle; Laouti, Mhamed; Ajina, Aymen

    2013-01-01

    In this paper, we investigate the empirical relationship between corporate governance and information asymmetry across a range of French firms. Based on a cross-sectional analysis, our study of the empirical relationship between corporate governance and information asymmetry involved 160 companies over the years 2008-2010. Mechanisms of corporate governance include the characteristics of the board of directors. Our results seem to indicate a significant relationship between certain mechani...

  6. Baryon asymmetry, inflation and squeezed states

    International Nuclear Information System (INIS)

    Bambah, Bindu A.; Chaitanya, K.V.S. Shiv; Mukku, C.

    2007-01-01

    We use the general formalism of squeezed rotated states to calculate baryon asymmetry in the wake of inflation through parametric amplification. We base our analysis on a B and CP violating Lagrangian in an isotropically expanding universe. The B and CP violating terms originate from the coupling of complex fields with non-zero baryon number to a complex background inflaton field. We show that a differential amplification of particle and antiparticle modes gives rise to baryon asymmetry

  7. Bottom production asymmetries at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Norrbin, E.; Vogt, R.

    1999-01-01

    We present results on bottom hadron production asymmetries at the LHC within both the Lund string fragmentation model and the intrinsic bottom model. The main aspects of the models are summarized and specific predictions for pp collisions at 14 TeV are given. Asymmetries are found to be very small at central rapidities increasing to a few percent at forward rapidities. At very large rapidities intrinsic production could dominate but this region is probably out of reach of any experiment.

  8. Bottom production asymmetries at the LHC

    International Nuclear Information System (INIS)

    Norrbin, E.; Vogt, R.

    1999-01-01

    We present results on bottom hadron production asymmetries at the LHC within both the Lund string fragmentation model and the intrinsic bottom model. The main aspects of the models are summarized and specific predictions for pp collisions at 14 TeV are given. Asymmetries are found to be very small at central rapidities increasing to a few percent at forward rapidities. At very large rapidities intrinsic production could dominate but this region is probably out of reach of any experiment

  9. Approach-avoidance activation without anterior asymmetry

    Directory of Open Access Journals (Sweden)

    Andero eUusberg

    2014-03-01

    Full Text Available Occasionally, the expected effects of approach-avoidance motivation on anterior EEG alpha asymmetry fail to emerge, particularly in studies using affective picture stimuli. These null findings have been explained by insufficient motivational intensity of, and/or overshadowing interindividual variability within the responses to emotional pictures. These explanations were systematically tested using data from 70 students watching 5 types of affective pictures ranging from very pleasant to unpleasant. The stimulus categories reliably modulated self-reports as well as the amplitude of late positive potential, an ERP component reflecting orienting towards motivationally significant stimuli. The stimuli did not, however, induce expected asymmetry effects either for the sample or individual participants. Even while systematic stimulus-dependent individual differences emerged in self-reports as well as LPP amplitudes, the asymmetry variability was dominated by stimulus-independent interindividual variability. Taken together with previous findings, these results suggest that under some circumstances anterior asymmetry may not be an inevitable consequence of core affect. Instead, state asymmetry shifts may be overpowered by stable trait asymmetry differences and/or stimulus-independent yet situation-dependent interindividual variability, possibly caused by processes such as emotion regulation or anxious apprehension.

  10. ``Green's function'' approach & low-mode asymmetries

    Science.gov (United States)

    Masse, Laurent; Clark, Dan; Salmonson, Jay; MacLaren, Steve; Ma, Tammy; Khan, Shahab; Pino, Jesse; Ralph, Jo; Czajka, C.; Tipton, Robert; Landen, Otto; Kyrala, Georges; 2 Team; 1 Team

    2017-10-01

    Long wavelength, low mode asymmetries are believed to play a leading role in limiting the performance of current ICF implosions on NIF. These long wavelength modes are initiated and driven by asymmetries in the x-ray flux from the hohlraum; however, the underlying hydrodynamics of the implosion also act to amplify these asymmetries. The work presented here aim to deepen our understanding of the interplay of the drive asymmetries and the underlying implosion hydrodynamics in determining the final imploded configuration. This is accomplished through a synthesis of numerical modeling, analytic theory, and experimental data. In detail, we use a Green's function approach to connect the drive asymmetry seen by the capsule to the measured inflight and hot spot symmetries. The approach has been validated against a suite of numerical simulations. Ultimately, we hope this work will identify additional measurements to further constrain the asymmetries and increase hohlraum illumination design flexibility on the NIF. The technique and derivation of associated error bars will be presented. LLC, (LLNS) Contract No. DE-AC52-07NA27344.

  11. Double-Stranded Peptide Nucleic Acids

    DEFF Research Database (Denmark)

    2001-01-01

    A novel class of compounds, known as peptide nucleic acids, form double-stranded structures with one another and with ssDNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.......A novel class of compounds, known as peptide nucleic acids, form double-stranded structures with one another and with ssDNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker....

  12. Asymmetric strand segregation: epigenetic costs of genetic fidelity?

    Directory of Open Access Journals (Sweden)

    Diane P Genereux

    2009-06-01

    Full Text Available Asymmetric strand segregation has been proposed as a mechanism to minimize effective mutation rates in epithelial tissues. Under asymmetric strand segregation, the double-stranded molecule that contains the oldest DNA strand is preferentially targeted to the somatic stem cell after each round of DNA replication. This oldest DNA strand is expected to have fewer errors than younger strands because some of the errors that arise on daughter strands during their synthesis fail to be repaired. Empirical findings suggest the possibility of asymmetric strand segregation in a subset of mammalian cell lineages, indicating that it may indeed function to increase genetic fidelity. However, the implications of asymmetric strand segregation for the fidelity of epigenetic information remain unexplored. Here, I explore the impact of strand-segregation dynamics on epigenetic fidelity using a mathematical-modelling approach that draws on the known molecular mechanisms of DNA methylation and existing rate estimates from empirical methylation data. I find that, for a wide range of starting methylation densities, asymmetric -- but not symmetric -- strand segregation leads to systematic increases in methylation levels if parent strands are subject to de novo methylation events. I found that epigenetic fidelity can be compromised when enhanced genetic fidelity is achieved through asymmetric strand segregation. Strand segregation dynamics could thus explain the increased DNA methylation densities that are observed in structured cellular populations during aging and in disease.

  13. The general atomic strand winding machine

    International Nuclear Information System (INIS)

    Matt, P.

    1976-01-01

    In conjunction with the integrated development of their high temperature gas cooled reactors (HTGR), General Atomic of San Diego, USA, also developed a strand winding system for the horizontal prestressing of pressure vessels. The machine lay-out, its capabilities and the test program carried out in the laboratory and on a full scale pressure vessel model are described. (author)

  14. Missing Strands? Dealing with Hair Loss

    Science.gov (United States)

    ... 2017 Print this issue Missing Strands? Dealing with Hair Loss En español Send us your comments Hair loss is often associated with men and aging, but ... or their treatments, and many other things cause hair loss. The most common type of hair loss is ...

  15. Untangling the Strands of the Fourteenth Amendment.

    Science.gov (United States)

    Lupu, Ira C.

    1979-01-01

    Explores trends in the Court's interpretation of the libertarian and egalitarian dimensions of the Fourteenth Amendment and offers a theory of the two strands. Available from Michigan Law Review, Hutchins Hall, Ann Arbor, MI 48109; single issues $3.50. (Author/IRT)

  16. The (not so immortal strand hypothesis

    Directory of Open Access Journals (Sweden)

    Cristian Tomasetti

    2015-03-01

    Significance: Utilizing an approach that is fundamentally different from previous efforts to confirm or refute the immortal strand hypothesis, we provide evidence against non-random segregation of DNA during stem cell replication. Our results strongly suggest that parental DNA is passed randomly to stem cell daughters and provides new insight into the mechanism of DNA replication in stem cells.

  17. The (not so) immortal strand hypothesis.

    Science.gov (United States)

    Tomasetti, Cristian; Bozic, Ivana

    2015-03-01

    Non-random segregation of DNA strands during stem cell replication has been proposed as a mechanism to minimize accumulated genetic errors in stem cells of rapidly dividing tissues. According to this hypothesis, an "immortal" DNA strand is passed to the stem cell daughter and not the more differentiated cell, keeping the stem cell lineage replication error-free. After it was introduced, experimental evidence both in favor and against the hypothesis has been presented. Using a novel methodology that utilizes cancer sequencing data we are able to estimate the rate of accumulation of mutations in healthy stem cells of the colon, blood and head and neck tissues. We find that in these tissues mutations in stem cells accumulate at rates strikingly similar to those expected without the protection from the immortal strand mechanism. Utilizing an approach that is fundamentally different from previous efforts to confirm or refute the immortal strand hypothesis, we provide evidence against non-random segregation of DNA during stem cell replication. Our results strongly suggest that parental DNA is passed randomly to stem cell daughters and provides new insight into the mechanism of DNA replication in stem cells. Copyright © 2015. Published by Elsevier B.V.

  18. SAKAMATA : A tool to avoid whale strandings

    NARCIS (Netherlands)

    Benders, F.P.A.; Beerens, S.P.; Verboom, W.C.

    2004-01-01

    World-wide a concern exists about the influence of man-made noise on marine life, and particularly of high power sonar. Most concern lies with marine mammals that use acoustics for hunting, communication and/or navigation. This concern is fed by recent strandings of whales that could be related to

  19. SAKAMATA : A tool to avoid whale strandings

    NARCIS (Netherlands)

    Benders, F.P.A.; Beerens, S.P.; Verboom, W.C.

    2002-01-01

    World-wide a concern exists about the influence of man-made noise on marine life, and particularly of high power sonar. Most concern lies with marine mammals that use acoustics for hunting, communication and/or navigation. This concern is fed by recent strandings of whales that could be related to

  20. Fragmentation in DNA double-strand breaks

    International Nuclear Information System (INIS)

    Wei Zhiyong; Suzhou Univ., Suzhou; Zhang Lihui; Li Ming; Fan Wo; Xu Yujie

    2005-01-01

    DNA double strand breaks are important lesions induced by irradiations. Random breakage model or quantification supported by this concept is suitable to analyze DNA double strand break data induced by low LET radiation, but deviation from random breakage model is more evident in high LET radiation data analysis. In this work we develop a new method, statistical fragmentation model, to analyze the fragmentation process of DNA double strand breaks. After charged particles enter the biological cell, they produce ionizations along their tracks, and transfer their energies to the cells and break the cellular DNA strands into fragments. The probable distribution of the fragments is obtained under the condition in which the entropy is maximum. Under the approximation E≅E 0 + E 1 l + E 2 l 2 , the distribution functions are obtained as exp(αl + βl 2 ). There are two components, the one proportional to exp(βl 2 ), mainly contributes to the low mass fragment yields, the other component, proportional to exp(αl), decreases slowly as the mass of the fragments increases. Numerical solution of the constraint equations provides parameters α and β. Experimental data, especially when the energy deposition is higher, support the statistical fragmentation model. (authors)

  1. Low-residue euthanasia of stranded mysticetes.

    Science.gov (United States)

    Harms, Craig A; McLellan, William A; Moore, Michael J; Barco, Susan G; Clarke, Elsburgh O; Thayer, Victoria G; Rowles, Teresa K

    2014-01-01

    Euthanasia of stranded large whales poses logistic, safety, pharmaceutical, delivery, public relations, and disposal challenges. Reasonable arguments may be made for allowing a stranded whale to expire naturally. However, slow cardiovascular collapse from gravitational effects outside of neutral buoyancy, often combined with severely debilitating conditions, motivate humane efforts to end the animal's suffering. The size of the animal and prevailing environmental conditions often pose safety concerns for stranding personnel, which take priority over other considerations. When considering chemical euthanasia, the size of the animal also necessitates large quantities of euthanasia agents. Drug residues are a concern for relay toxicity to scavengers, particularly for pentobarbital-containing euthanasia solutions. Pentobarbital is also an environmental concern because of its stability and long persistence in aquatic environments. We describe a euthanasia technique for stranded mysticetes using readily available, relatively inexpensive, preanesthetic and anesthetic drugs (midazolam, acepromazine, xylazine) followed by saturated KCl delivered via custom-made needles and a low-cost, basic, pressurized canister. This method provides effective euthanasia while moderating personnel exposure to hazardous situations and minimizing drug residues of concern for relay toxicity.

  2. [Orthodontic treatment of Class III patients with mandibular asymmetry].

    Science.gov (United States)

    Duan, Yin-Zhong; Huo, Na; Chen, Lei; Chen, Xue-Peng; Lin, Yang

    2008-12-01

    To investigate the treatment outcome of Class III patients with dental, functional and mild skeletal mandibular asymmetry. Thirty-five patients (14 males and 21 females) with dental, functional and mild skeletal mandibular asymmetry were selected. The age range of the patients was 7 - 22 years with a mean age of 16.5 years. Dental mandibular asymmetry was treated with expansion of maxillary arch to help the mandible returning to normal position. Functional mandibular asymmetry was treated with activator or asymmetrical protraction and Class III elastics. Mild skeletal mandibular asymmetry was treated with camouflage treatment. Good occlusal relationships were achieved and facial esthetics was greatly improved after orthodontic treatment in patients with dental and functional mandibular asymmetry. However, patients with skeletal mandibular asymmetry should be treated with both extraction and genioplasty. Orthodontic treatment was suitable for patients with dental and functional mandibular asymmetry, while combined orthodontics and surgery could get good results in patients with skeletal mandibular asymmetry.

  3. Oil demand asymmetry in the OECD

    International Nuclear Information System (INIS)

    Shealy, M.T.

    1990-01-01

    Oil demand asymmetry exists, is significant, and can be captured with a simple demand equation using a Pmax term. The unstable parameters of the original symmetric equations suggest misspecification. Addition of a Pmax term to represent asymmetry yields stable parameters from 1982 through 1989 and so suggests proper specification. Asymmetry is significant because the short-run (and long-run) price elasticity is less than half as large when oil price falls as when price rises beyond the past peak. The lower elasticity applies both to price decreases and also to price increases for which price remains below the past peak. As long as the real oil price remains well below the 1981 peak, asymmetry implies that OECD oil demand should be less sensitive to oil price variations than in 1981. More specifically, the results shown suggest that today's oil demand elasticity should be less than half as large as the elasticity for a price increase in 1981. Forecasts from the asymmetric equations are significantly higher than the DOE base-case forecast. DOE's lower forecast is due to greater price asymmetry through 1995 and to higher long-run price elasticity beyond 1995. One reason for the higher long-run price elasticity might be greater assumed improvements in energy-efficiency than implied by the historical data

  4. The Inherent Asymmetry of DNA Replication.

    Science.gov (United States)

    Snedeker, Jonathan; Wooten, Matthew; Chen, Xin

    2017-10-06

    Semiconservative DNA replication has provided an elegant solution to the fundamental problem of how life is able to proliferate in a way that allows cells, organisms, and populations to survive and replicate many times over. Somewhat lost, however, in our admiration for this mechanism is an appreciation for the asymmetries that occur in the process of DNA replication. As we discuss in this review, these asymmetries arise as a consequence of the structure of the DNA molecule and the enzymatic mechanism of DNA synthesis. Increasing evidence suggests that asymmetries in DNA replication are able to play a central role in the processes of adaptation and evolution by shaping the mutagenic landscape of cells. Additionally, in eukaryotes, recent work has demonstrated that the inherent asymmetries in DNA replication may play an important role in the process of chromatin replication. As chromatin plays an essential role in defining cell identity, asymmetries generated during the process of DNA replication may play critical roles in cell fate decisions related to patterning and development.

  5. Asymmetry of the Brain: Development and Implications.

    Science.gov (United States)

    Duboc, Véronique; Dufourcq, Pascale; Blader, Patrick; Roussigné, Myriam

    2015-01-01

    Although the left and right hemispheres of our brains develop with a high degree of symmetry at both the anatomical and functional levels, it has become clear that subtle structural differences exist between the two sides and that each is dominant in processing specific cognitive tasks. As the result of evolutionary conservation or convergence, lateralization of the brain is found in both vertebrates and invertebrates, suggesting that it provides significant fitness for animal life. This widespread feature of hemispheric specialization has allowed the emergence of model systems to study its development and, in some cases, to link anatomical asymmetries to brain function and behavior. Here, we present some of what is known about brain asymmetry in humans and model organisms as well as what is known about the impact of environmental and genetic factors on brain asymmetry development. We specifically highlight the progress made in understanding the development of epithalamic asymmetries in zebrafish and how this model provides an exciting opportunity to address brain asymmetry at different levels of complexity.

  6. Measurement of Z0 lepton coupling asymmetries

    International Nuclear Information System (INIS)

    Smy, M.B.

    1997-07-01

    Polarized Z 0 's from e + e - collisions at the SLAC Linear Collider (SLC) have been used to determine the asymmetry parameters A e , A μ and A τ from the leptonic decay channels. This is the first direct measurement of A μ . The data have been gathered by the SLC Large Detector (SLD) with the electron polarization averaging 63% during the 1993 data taking period and 77% in 1994-95. A maximum likelihood procedure as well as cross section asymmetries was used to measure the asymmetry parameters from the differential cross sections for equal luminosities of left- and right-handed electron beams. The polarization-dependent muon-pair distributions give A μ = 0.102 ±0.034 and the tau-pairs give A τ = 0.195 ±0.034. The initial state electronic couplings in all three leptonic channels as well as the final state angular distribution in the e + e - final state measure A e to be A e = 0.152±0.012. Assuming lepton universality and defining a global leptonic asymmetry parameter A e-μ-τ = 0.151±0.011. This global leptonic asymmetry value translates directly into sin 2 θ W eff =0.2310±0.0014 at the Z 0 pole

  7. KARAKTERISTIK ORIENTED STRAND BOARD DARI KAYU AKASIA DAN AFRIKA BERDASARKAN PENYUSUNAN ARAH STRAND

    Directory of Open Access Journals (Sweden)

    Nurhaida

    2008-04-01

    Full Text Available The research objectives arc to evaluate physical and mechanical properties of OSB based on strands orientation; and to evaluate physical and mechanical properties of OSB made from akasia wood (Acacia mangium Wild and afrika wood (Maesopsis eminii Engl. Akasia and afrika wood are used for OSB strand material with phenol formaldehyde (PF as adhesives and addition of paraffin. OSB made in this research is consist of three plies whereas are differed into eight (8 strand orientations. In the making process, hot press was carried out at 160OC and pressure 25kg.cm-2 for 15 minutes. Determination of OSB physical and mechanical properties is referred to JIS A 5908-2003. Result showed that strand orientations has no affect to OSB physical properties except for linicr swelling 24h, but it significantly influence all mechanical properties of OSB. Wood species have an effect on mechanical properties of OSB in the dry test, wet MOE lengthwise test and OSB physical properties, particularly to OSB density and water absorbing capability at 2h and 24h. All of OSB physical properties arc meet JIS A 5908-2003 standard, but not all of the mechanical properties such as dry MOE lengthwise, dry MOE and MOR widthwise. The best physical and mechanical properties is presented by OSB made from akasia wood in strand orientation F, G, Band C whereas all parameters meet JIS A 5908-2003 standard. In comparation with strand orientation B that is frequent used in industry, strand orientation F and G arc proficient to raise the modulus elasticity value (MOE and strength (MOR as much as 167.81-231.65% and 89.73-109.87%, respectively; especially in widthwise board application. Furthermore, strand orientation F and G arc more flexible as structural components

  8. Southeast Region Level A Marine Mammal Stranding Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data on marine mammal strandings are collected by the Southeast Marine Mammal Stranding Network. Basic data on the location, species identification, animal...

  9. Corrosion characteristics of unprotected post-tensioning strands under stress.

    Science.gov (United States)

    2014-05-01

    An investigation was conducted to determine the effect of stress condition : and environmental exposure on corrosion of post-tensioned strands during ungrouted periods. : Exposures for periods of up to 4 weeks of stressed, as-received strand placed i...

  10. Asymmetry dependence of the nuclear caloric curve

    International Nuclear Information System (INIS)

    McIntosh, A.B.; Bonasera, A.; Cammarata, P.; Hagel, K.; Heilborn, L.; Kohley, Z.; Mabiala, J.; May, L.W.; Marini, P.; Raphelt, A.; Souliotis, G.A.; Wuenschel, S.; Zarrella, A.; Yennello, S.J.

    2013-01-01

    A basic feature of the nuclear equation of state is not yet understood: the dependence of the nuclear caloric curve on the neutron–proton asymmetry. Predictions of theoretical models differ on the magnitude and even the sign of this dependence. In this work, the nuclear caloric curve is examined for fully reconstructed quasi-projectiles around mass A=50. The caloric curve extracted with the momentum quadrupole fluctuation thermometer shows that the temperature varies linearly with quasi-projectile asymmetry (N−Z)/A . An increase in asymmetry of 0.15 units corresponds to a decrease in temperature on the order of 1 MeV. These results also highlight the importance of a full quasi-projectile reconstruction in the study of thermodynamic properties of hot nuclei

  11. The electroweak polarization asymmetry: A guided tour

    International Nuclear Information System (INIS)

    Kennedy, D.C.

    1988-10-01

    A comprehensive review is provided of the electroweak polarization asymmetry at the Z 0 , a highly accurate measure of the Z 0 coupling to fermions. Its significance as a precision test of the Standard Model is explored in detail. Emphasized are the role of electroweak symmetry-breaking and radiative corrections; the non-decoupling of new physics beyond the Z 0 ; and the testing of extensions of the Standard Model, such as supersymmetry, technicolor, new generations of fermions, grand unification, and new gauge forces. Also discussed are the relationship of the polarization asymmetry to other electroweak observables and its superiority to other Z 0 asymmetries. Experimental issues are briefly presented, stressing the importance of polarization at the SLC and LEP e + e - colliders. 42 refs., 13 figs., 2 tabs

  12. Superheavy thermal dark matter and primordial asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Bramante, Joseph [Perimeter Institute for Theoretical Physics,31 Caroline St N, Waterloo, ON N2L 2Y5 (Canada); Unwin, James [Department of Physics, University of Illinois at Chicago,845 W Taylor St, Chicago, IL 60607 (United States)

    2017-02-23

    The early universe could feature multiple reheating events, leading to jumps in the visible sector entropy density that dilute both particle asymmetries and the number density of frozen-out states. In fact, late time entropy jumps are usually required in models of Affleck-Dine baryogenesis, which typically produces an initial particle-antiparticle asymmetry that is much too large. An important consequence of late time dilution, is that a smaller dark matter annihilation cross section is needed to obtain the observed dark matter relic density. For cosmologies with high scale baryogenesis, followed by radiation-dominated dark matter freeze-out, we show that the perturbative unitarity mass bound on thermal relic dark matter is relaxed to 10{sup 10} GeV. We proceed to study superheavy asymmetric dark matter models, made possible by a sizable entropy injection after dark matter freeze-out, and identify how the Affleck-Dine mechanism would generate the baryon and dark asymmetries.

  13. Superheavy thermal dark matter and primordial asymmetries

    International Nuclear Information System (INIS)

    Bramante, Joseph; Unwin, James

    2017-01-01

    The early universe could feature multiple reheating events, leading to jumps in the visible sector entropy density that dilute both particle asymmetries and the number density of frozen-out states. In fact, late time entropy jumps are usually required in models of Affleck-Dine baryogenesis, which typically produces an initial particle-antiparticle asymmetry that is much too large. An important consequence of late time dilution, is that a smaller dark matter annihilation cross section is needed to obtain the observed dark matter relic density. For cosmologies with high scale baryogenesis, followed by radiation-dominated dark matter freeze-out, we show that the perturbative unitarity mass bound on thermal relic dark matter is relaxed to 10 10 GeV. We proceed to study superheavy asymmetric dark matter models, made possible by a sizable entropy injection after dark matter freeze-out, and identify how the Affleck-Dine mechanism would generate the baryon and dark asymmetries.

  14. CP asymmetries in semiinclusive B0 decays

    Energy Technology Data Exchange (ETDEWEB)

    Dunietz, Isard

    1999-02-01

    It was recently pointed out that inclusive B^0(t) decays could show CP violation. The totally inclusive asymmetry is expected to be tiny [O(10^{-3})] because of large cancellations among the asymmetries in the charmless, single charm and double charm final states. Enriching particular final state configurations could significantly increase the CP-asymmetry and observability. Such studies can extract fundamental CKM (Cabibbo-Kobayashi-Maskawa) parameters, and (perhaps) even Delta m(B_s). A superb vertex detector could see CP violation with 10^5 (10^6) flavor-tagged B_s (B_d) mesons within the CKM model. Because the effects could be significantly larger due to new physics, they should be searched for in existing or soon available data samples.

  15. Asymmetry in power-law magnitude correlations.

    Science.gov (United States)

    Podobnik, Boris; Horvatić, Davor; Tenenbaum, Joel N; Stanley, H Eugene

    2009-07-01

    Time series of increments can be created in a number of different ways from a variety of physical phenomena. For example, in the phenomenon of volatility clustering-well-known in finance-magnitudes of adjacent increments are correlated. Moreover, in some time series, magnitude correlations display asymmetry with respect to an increment's sign: the magnitude of |x_{i}| depends on the sign of the previous increment x_{i-1} . Here we define a model-independent test to measure the statistical significance of any observed asymmetry. We propose a simple stochastic process characterized by a an asymmetry parameter lambda and a method for estimating lambda . We illustrate both the test and process by analyzing physiological data.

  16. Do gasoline prices exhibit asymmetry? Not usually

    International Nuclear Information System (INIS)

    Douglas, Christopher C.

    2010-01-01

    Previous studies have found evidence of asymmetric price adjustment in U.S. retail gasoline prices in that gasoline prices rise more rapidly in response to a cost increase than fall in response to a cost decrease. By estimating a threshold cointegration model that allows for multiple regimes, I am able to test how sensitive this result is to outlying observations. In contrast to previous studies, I find little evidence of asymmetry for the vast majority of observations and that the asymmetry is being driven by a small number of outlying observations. (author)

  17. The gluon Sivers asymmetry measurements at COMPASS

    CERN Document Server

    Szabelski, Adam

    2018-01-01

    The Sivers function describes the correlation between the transverse spin of a nucleon and the transverse motion of its partons. As such, a nonzero Sivers effect for gluons could be a signature of their nonzero orbital angular momentum inside the nucleon. COMPASS has collected data of semi-inclusive deep inelastic scattering by impinging 160 GeV/$c$ muons on transversely polarised proton and deuteron targets. The gluon Sivers asymmetry is extracted from a high-$p_T$ hadron pair sample with the use of monte carlo simulations and the a neural network approach. The results of a similar analysis for a Collins-like asymmetry for gluons will also be given.

  18. The gluon Sivers asymmetry measurements at COMPASS

    CERN Document Server

    Szabelski, Adam

    2017-01-01

    The Sivers function describes the correlation between the transverse spin of a nucleon and the transverse motion of its partons. As such, a nonzero Sivers effect for gluons could be a signature of their nonzero orbital angular momentum inside the nucleon. COMPASS has collected data of semi-inclusive deep inelastic scattering by impinging 160 GeV/$c$ muons on transversely polarised proton and deuteron targets. The gluon Sivers asymmetry is extracted from a high-$p_T$ hadron pair sample with the use of monte carlo simulations and the a neural network approach. The results of a similar analysis for a Collins-like asymmetry for gluons will also be given.

  19. A mass stranding of the squid martialia hyadesi Rochebrune and ...

    African Journals Online (AJOL)

    1997-02-11

    Feb 11, 1997 ... All animals were immature, with females in lower stages of maturity than males. No predatory marine mammals were seen in the area during or after the stranding event. An interpretation of the stranding is presented with reference to historical reports of squid strandings worldwide. Evidence suggests some ...

  20. The European Nb3Sn advanced strand development programme

    International Nuclear Information System (INIS)

    Vostner, A.; Salpietro, E.

    2005-01-01

    Strands relevant for fusion with high critical current densities and moderate hysteresis losses were developed and already produced on industrial scale. Based on these achievements EFDA-CSU Garching has launched a Nb 3 Sn strand development and procurement action inside Europe in order to assess the current status of the Nb 3 Sn strand production capability. All six addressed companies have replied positively to the strand R and D programme which includes the three major Nb 3 Sn production techniques namely the bronze, internal-tin and powder-in-tube (PIT) route. According to the strand requirements for the ITER TF conductor a critical current density of 800 A/mm 2 (at 12 T, 4.2 K and 10 μV/m) and overall strand hysteresis losses below 500 kJ/m 3 have been specified as the minimum guaranteed strand performance. The second major objective of this programme is to motivate the strand manufacturers to develop and design high performance Nb 3 Sn strands optimised for the ITER conductor. For this purpose, a target critical current density of 1100 A/mm 2 has been added to the specification. This paper describes the strategy behind the strand development programme, the actual status of the strand production as well as first preliminary results obtained from the strand suppliers

  1. Strand displacement by DNA polymerase III occurs through a tau-psi-chi link to single-stranded DNA-binding protein coating the lagging strand template.

    Science.gov (United States)

    Yuan, Quan; McHenry, Charles S

    2009-11-13

    In addition to the well characterized processive replication reaction catalyzed by the DNA polymerase III holoenzyme on single-stranded DNA templates, the enzyme possesses an intrinsic strand displacement activity on flapped templates. The strand displacement activity is distinguished from the single-stranded DNA-templated reaction by a high dependence upon single-stranded DNA binding protein and an inability of gamma-complex to support the reaction in the absence of tau. However, if gamma-complex is present to load beta(2), a truncated tau protein containing only domains III-V will suffice. This truncated protein is sufficient to bind both the alpha subunit of DNA polymerase (Pol) III and chipsi. This is reminiscent of the minimal requirements for Pol III to replicate short single-stranded DNA-binding protein (SSB)-coated templates where tau is only required to serve as a scaffold to hold Pol III and chi in the same complex (Glover, B., and McHenry, C. (1998) J. Biol. Chem. 273, 23476-23484). We propose a model in which strand displacement by DNA polymerase III holoenzyme depends upon a Pol III-tau-psi-chi-SSB binding network, where SSB is bound to the displaced strand, stabilizing the Pol III-template interaction. The same interaction network is probably important for stabilizing the leading strand polymerase interactions with authentic replication forks. The specificity constant (k(cat)/K(m)) for the strand displacement reaction is approximately 300-fold less favorable than reactions on single-stranded templates and proceeds with a slower rate (150 nucleotides/s) and only moderate processivity (approximately 300 nucleotides). PriA, the initiator of replication restart on collapsed or misassembled replication forks, blocks the strand displacement reaction, even if added to an ongoing reaction.

  2. Mandibular asymmetry and the fourth dimension.

    Science.gov (United States)

    Kaban, Leonard B

    2009-03-01

    This paper represents more than 30 years of discussion and collaboration with Drs Joseph Murray and John Mulliken in an attempt to understand growth patterns over time (ie, fourth dimension) in patients with hemifacial microsomia (HFM). This is essential for the development of rational treatment protocols for children and adults with jaw asymmetry. Traditionally, HFM was thought of as a unilateral deformity, but it was recognized that 20% to 30% of patients had bilateral abnormalities. However, early descriptions of skeletal correction addressed almost exclusively lengthening of the short (affected) side of the face. Based on longitudinal clinical observations of unoperated HFM patients, we hypothesized that abnormal mandibular growth is the earliest skeletal manifestation and that restricted growth of the mandible plays a pivotal role in progressive distortion of both the ipsilateral and contralateral facial skeleton. This hypothesis explains the progressive nature of the asymmetry in patients with HFM and provides the rationale for surgical lengthening of the mandible in children to prevent end-stage deformity. During the past 30 years, we have learned that this phenomenon of progressive distortion of the adjacent and contralateral facial skeleton occurs with other asymmetric mandibular undergrowth (tumor resection, radiation therapy, or posttraumatic defects) and overgrowth (mandibular condylar hyperplasia) conditions. In this paper, I describe the progression of deformity with time in patients with mandibular asymmetry as a result of undergrowth and overgrowth. Understanding these concepts is critical for the development of rational treatment protocols for adults with end-stage asymmetry and for children to minimize secondary deformity.

  3. Measuring Asymmetry in Insect-Plant Networks

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, Claudia P T [Programa de Pos-Graduacao em Fisica, Universidade Federal do Rio Grande do Norte, UFRN - Campus Universitario, Lagoa Nova, CEP 59078 972, Natal, RN (Brazil); De Almeida, Adriana M [Departamento de Botanica, Ecologia e Zoologia, Centro de Biociencias, Universidade Federal do Rio Grande do Norte, UFRN - Campus Universitario, Lagoa Nova, CEP 59078 972, Natal, RN (Brazil); Corso, Gilberto, E-mail: claudia@dfte.ufrn.br, E-mail: adrianam@ufrn.br, E-mail: corso@cb.ufrn.br [Departamento de Biofisica e Farmacologia, Centro de Biociencias, Universidade Federal do Rio Grande do Norte, UFRN - Campus Universitario, Lagoa Nova, CEP 59078 972, Natal, RN (Brazil)

    2011-03-01

    In this work we focus on interaction networks between insects and plants and in the characterization of insect plant asymmetry, an important issue in coevolution and evolutionary biology. We analyze in particular the asymmetry in the interaction matrix of animals (herbivorous insects) and plants (food resource for the insects). Instead of driving our attention to the interaction matrix itself we derive two networks associated to the bipartite network: the animal network, D{sub 1}, and the plant network, D{sub 2}. These networks are constructed according to the following recipe: two animal species are linked once if they interact with the same plant. In a similar way, in the plant network, two plants are linked if they interact with the same animal. To explore the asymmetry between D{sub 2} and D{sub 1} we test for a set of 23 networks from the ecologic literature networks: the difference in size, {Delta}L, clustering coefficient difference, {Delta}C, and mean connectivity difference, {Delta}. We used a nonparametric statistical test to check the differences in {Delta}L, {Delta}C and {Delta}. Our results indicate that {Delta}L and {Delta} show a significative asymmetry.

  4. Frontal Brain Asymmetry and Willingness to Pay.

    Science.gov (United States)

    Ramsøy, Thomas Z; Skov, Martin; Christensen, Maiken K; Stahlhut, Carsten

    2018-01-01

    Consumers frequently make decisions about how much they are willing to pay (WTP) for specific products and services, but little is known about the neural mechanisms underlying such calculations. In this study, we were interested in testing whether specific brain activation-the asymmetry in engagement of the prefrontal cortex-would be related to consumer choice. Subjects saw products and subsequently decided how much they were willing to pay for each product, while undergoing neuroimaging using electroencephalography. Our results demonstrate that prefrontal asymmetry in the gamma frequency band, and a trend in the beta frequency band that was recorded during product viewing was significantly related to subsequent WTP responses. Frontal asymmetry in the alpha band was not related to WTP decisions. Besides suggesting separate neuropsychological mechanisms of consumer choice, we find that one specific measure-the prefrontal gamma asymmetry-was most strongly related to WTP responses, and was most coupled to the actual decision phase. These findings are discussed in light of the psychology of WTP calculations, and in relation to the recent emergence of consumer neuroscience and neuromarketing.

  5. Frontal Brain Asymmetry and Willingness to Pay

    DEFF Research Database (Denmark)

    Ramsøy, Thomas Z.; Skov, Martin; Christensen, Maiken K.

    2018-01-01

    measure-the prefrontal gamma asymmetry-was most strongly related to WTP responses, and was most coupled to the actual decision phase. These findings are discussed in light of the psychology of WTP calculations, and in relation to the recent emergence of consumer neuroscience and neuromarketing....

  6. Human cerebral asymmetries evaluated by computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Chang Chui, H; Damasio, A R [Iowa Univ., Iowa City (USA)

    1980-10-01

    The handedness of seventy-five persons without evidence of neurological disease, was assessed with a standardised test. An analysis of the CT scans of the same persons was performed to determine (1) presence and lateralisation of frontal and occipital 'petalia', (2) width of frontal and occipital lobes of each hemisphere, (3) direction of straight sinus deviation. Results suggest that handedness and cerebral asymmetries are independent variables. There were no significant differences between right-handers and non-right handers. Also there was no significant differences between strongly left-handed and ambidextrous individuals, nor were there differences between right-handers with or without family history of left-handedness. Irrespective of handedness, left occipital 'petalia' was more common than right (p<0.01), right frontal petalia was more common than left (p<0.01), and straight sinus deviation was more commonly toward the right. The study does not support the concept that cerebral 'symmetry' or 'reverse asymmetry' are associated with left-handedness or ambidexterity. The noted asymmetries are more likely to be direct correlates of cerebral language dominance, than of handedness. Outside forces acting on the bone may also contribute to the asymmetries. CT scan may be of value as a direct predictor of cerebral dominance.

  7. Introduction "Workplace (a)symmetries: multimodal perspectives"

    DEFF Research Database (Denmark)

    Asmuss, Birte

    studied in everyday and professional settings (Ariss, 2009; Glenn, 2010; Maynard, 1991; Roberts, 2000; Robinson, 2001). Numerous studies have pointed out that (a)symmetries in talk can be results of underlying interactional micro-practices like uneven turn distribution and question-answer formats...

  8. Binomial distribution for the charge asymmetry parameter

    International Nuclear Information System (INIS)

    Chou, T.T.; Yang, C.N.

    1984-01-01

    It is suggested that for high energy collisions the distribution with respect to the charge asymmetry z = nsub(F) - nsub(B) is binomial, where nsub(F) and nsub(B) are the forward and backward charge multiplicities. (orig.)

  9. Effect of stress on structural brain asymmetry

    Czech Academy of Sciences Publication Activity Database

    Zach, P.; Valeš, Karel; Stuchlík, Aleš; Čermáková, P.; Mrzílková, J.; Koutella, A.; Kutová, M.

    2016-01-01

    Roč. 37, č. 4 (2016), s. 253-264 ISSN 0172-780X R&D Projects: GA ČR(CZ) GBP304/12/G069 Institutional support: RVO:67985823 Keywords : laterality * asymmetry * brain * evolution * stress * neuropsychiatric disorders Subject RIV: FH - Neurology Impact factor: 0.918, year: 2016

  10. Hemispheric and facial asymmetry: faces of academe.

    Science.gov (United States)

    Smith, W M

    1998-11-01

    Facial asymmetry (facedness) of selected academic faculty members was studied in relation to brain asymmetry and cognitive specialization. Comparisons of facedness were made among humanities faculty (H), faculty members of mathematics and physics (M-P), psychologists (P), and a group of randomly selected individuals (R). Facedness was defined in terms of the relative sizes (in square centimeters) of the two hemifaces. It was predicted that the four groups would show differences in facedness, namely, H, right face bias; M-P, left face bias; P, no bias; and R, no bias. The predictions were confirmed, and the results interpreted in terms of known differences in hemispheric specialization of cognitive functions as they relate to the dominant cognitive activity of each of the different groups. In view of the contralateral control of the two hemifaces (below the eyes) by the two hemispheres of the brain, the two sides of the face undergo differential muscular development, thus creating facial asymmetry. Other factors, such as gender, also may affect facial asymmetry. Suggestions for further research on facedness are discussed.

  11. Baryon asymmetry from Planck-scale physics

    International Nuclear Information System (INIS)

    Gelmini, G.; Holman, R.; Carnegie-Mellon Univ., Pittsburgh, PA

    1992-06-01

    It has been noted recently that Planck scale physics may induce the explicit breaking of global symmetries. We point out that in Majoron models, these explicit breakings, combined with sphaleron induced violation of B + L can give rise to the baryon asymmetry of the Universe

  12. Human cerebral asymmetries evaluated by computed tomography

    International Nuclear Information System (INIS)

    Chang Chui, H.; Damasio, A.R.

    1980-01-01

    The handedness of seventy-five persons without evidence of neurological disease, was assessed with a standardised test. An analysis of the CT scans of the same persons was performed to determine (1) presence and lateralisation of frontal and occipital 'petalia', (2) width of frontal and occipital lobes of each hemisphere, (3) direction of straight sinus deviation. Results suggest that handedness and cerebral asymmetries are independent variables. There were no significant differences between right-handers and non-right handers. Also there was no significant differences between strongly left-handed and ambidextrous individuals, nor were there differences between right-handers with or without family history of left-handedness. Irrespective of handedness, left occipital 'petalia' was more common than right (p<0.01), right frontal petalia was more common than left (p<0.01), and straight sinus deviation was more commonly toward the right. The study does not support the concept that cerebral 'symmetry' or 'reverse asymmetry' are associated with left-handedness or ambidexterity. The noted asymmetries are more likely to be direct correlates of cerebral language dominance, than of handedness. Outside forces acting on the bone may also contribute to the asymmetries. CT scan may be of value as a direct predictor of cerebral dominance. (author)

  13. An innovative design for using flexible printed coils for magnetostrictive-based longitudinal guided wave sensors in steel strand inspection

    International Nuclear Information System (INIS)

    Tse, P W; Liu, X C; Wang, X J; Liu, Z H; Wu, B; He, C F

    2011-01-01

    Magnetostrictive sensors (MsSs) that can excite and receive guided waves are commonly used in detecting defects that may occur in cables and strands for supporting heavy structures. A conventional MsS has a hard sensing coil that is wound onto a bobbin with electric wires to generate the necessary dynamic magnetic field to excite the desired guided waves. This tailor-made hard coil is usually bulky and is not flexible enough to fit steel strands of various sizes. The conventional MsS also cannot be mounted to any steel strand that does not have a free end to allow the bobbin to pass through the structure of the tested strand. Such inflexibilities limit the use of conventional MsSs in practical situations. To solve these limitations, an innovative type of coil, called a flexible printed coil (FPC), which is made out of flexible printed film, has been designed to replace the inflexible hard coil. The flexible structure of the FPC ensures that the new MsS can be easily installed on and removed from steel strands with different diameters and without free ends. Moreover, the FPC-based MsS can be wrapped into multiple layers due to its thin and flexible design. Although multi-layer FPC creates a minor asymmetry in the dynamic magnetic field, the results of finite element analysis and experiments confirm that the longitudinal guided waves excited by a FPC-based MsS are comparable to those excited by a conventional hard coil MsS. No significant reduction in defect inspection performance was found; in fact, further advantages were identified when using the FPC-based MsS. When acting as the transmitter, the innovative FPC-based MsS can cover a longer inspection length of strand. When acting as the receiver, the FPC-based MsS is more sensitive to smaller defects that are impossible to detect using a hard coil MsS. Hence, the multi-layer FPC-based MsS has great potential for replacing the conventional hard coil MsS because of its convenient installation, and ease of fitting to

  14. Development of strand burner for solid propellant burning rate studies

    International Nuclear Information System (INIS)

    Aziz, A; Mamat, R; Ali, W K Wan

    2013-01-01

    It is well-known that a strand burner is an apparatus that provides burning rate measurements of a solid propellant at an elevated pressure in order to obtain the burning characteristics of a propellant. This paper describes the facilities developed by author that was used in his studies. The burning rate characteristics of solid propellant have be evaluated over five different chamber pressures ranging from 1 atm to 31 atm using a strand burner. The strand burner has a mounting stand that allows the propellant strand to be mounted vertically. The strand was ignited electrically using hot wire, and the burning time was recorded by electronic timer. Wire technique was used to measure the burning rate. Preliminary results from these techniques are presented. This study shows that the strand burner can be used on propellant strands to obtain accurate low pressure burning rate data

  15. Photon asymmetry from radiative muon capture on 40Ca

    International Nuclear Information System (INIS)

    Larabee, A.J.; Burnham, R.A.; Gorringe, T.P.; Hasinoff, M.D.; Horvath, D.; Noble, A.J.; Pouladdej, A.; Virtue, C.J.; Azuelos, G.; Robertson, B.C.; Wright, D.H.

    1989-01-01

    The photon asymmetry (α γ) for 40 Ca has been measured at TRIUMF using the muon spin-rotation technique. From the asymmetry measurement, the value of the pseudoscalar coupling constant, g p , can be obtained. A total of 5500 clean photon events were collected. The preliminary value found for the photon asymmetry of 40 Ca is 1.00 ± 0.23

  16. Cerebral asymmetry in a selected Chinese population

    International Nuclear Information System (INIS)

    Wang, Y.X.; He, G.X.; Tong, G.H.; Wang, D.B.; Xu, K.Y.

    1999-01-01

    Previous studies have demonstrated anatomical differences between the two cerebral hemispheres and ethnic differences in cerebral asymmetry. This study examined asymmetry of Chinese living in Shanghai. Measurements were taken across the frontal, mid-cerebral and occipital regions from normal head computed tomography (CT) scans of 200 Chinese Shanghai residents (100 male and 100 female, aged 6-73 years, average 48.7 years). The results were compared with reported data in the literature. The following results were found: (i) In the frontal region the right side was larger than the left in 57.5% of cases, equal in 10.5% and smaller in 32% of cases; in the mid-cerebral region the right side was larger than the left in 65.5% of cases, equal in 12.5% and smaller in 22% of cases; in the occipital regions the right side was larger than the left in 34.5% of cases, equal in 8.5% and smaller in 57% of cases. The average right-left differences between the frontal, mid-cerebral and occipital regions were 0.43 mm, 0.9 mm and 0.4 mm respectively. No difference in cerebral asymmetry existed between males and females. The occipital lobes showed the greatest individual asymmetry. The distribution of cerebral asymmetry of Chinese in Shanghai showed similarity to North American Whites rather than North American Blacks, but the average right-left differences were smaller than those of Whites. Copyright (1999) Blackwell Science Pty Ltd

  17. The multiple personalities of Watson and Crick strands.

    Science.gov (United States)

    Cartwright, Reed A; Graur, Dan

    2011-02-08

    In genetics it is customary to refer to double-stranded DNA as containing a "Watson strand" and a "Crick strand." However, there seems to be no consensus in the literature on the exact meaning of these two terms, and the many usages contradict one another as well as the original definition. Here, we review the history of the terminology and suggest retaining a single sense that is currently the most useful and consistent. The Saccharomyces Genome Database defines the Watson strand as the strand which has its 5'-end at the short-arm telomere and the Crick strand as its complement. The Watson strand is always used as the reference strand in their database. Using this as the basis of our standard, we recommend that Watson and Crick strand terminology only be used in the context of genomics. When possible, the centromere or other genomic feature should be used as a reference point, dividing the chromosome into two arms of unequal lengths. Under our proposal, the Watson strand is standardized as the strand whose 5'-end is on the short arm of the chromosome, and the Crick strand as the one whose 5'-end is on the long arm. Furthermore, the Watson strand should be retained as the reference (plus) strand in a genomic database. This usage not only makes the determination of Watson and Crick unambiguous, but also allows unambiguous selection of reference stands for genomics. This article was reviewed by John M. Logsdon, Igor B. Rogozin (nominated by Andrey Rzhetsky), and William Martin.

  18. The multiple personalities of Watson and Crick strands

    Directory of Open Access Journals (Sweden)

    Graur Dan

    2011-02-01

    Full Text Available Abstract Background In genetics it is customary to refer to double-stranded DNA as containing a "Watson strand" and a "Crick strand." However, there seems to be no consensus in the literature on the exact meaning of these two terms, and the many usages contradict one another as well as the original definition. Here, we review the history of the terminology and suggest retaining a single sense that is currently the most useful and consistent. Proposal The Saccharomyces Genome Database defines the Watson strand as the strand which has its 5'-end at the short-arm telomere and the Crick strand as its complement. The Watson strand is always used as the reference strand in their database. Using this as the basis of our standard, we recommend that Watson and Crick strand terminology only be used in the context of genomics. When possible, the centromere or other genomic feature should be used as a reference point, dividing the chromosome into two arms of unequal lengths. Under our proposal, the Watson strand is standardized as the strand whose 5'-end is on the short arm of the chromosome, and the Crick strand as the one whose 5'-end is on the long arm. Furthermore, the Watson strand should be retained as the reference (plus strand in a genomic database. This usage not only makes the determination of Watson and Crick unambiguous, but also allows unambiguous selection of reference stands for genomics. Reviewers This article was reviewed by John M. Logsdon, Igor B. Rogozin (nominated by Andrey Rzhetsky, and William Martin.

  19. Protected DNA strand displacement for enhanced single nucleotide discrimination in double-stranded DNA.

    Science.gov (United States)

    Khodakov, Dmitriy A; Khodakova, Anastasia S; Huang, David M; Linacre, Adrian; Ellis, Amanda V

    2015-03-04

    Single nucleotide polymorphisms (SNPs) are a prime source of genetic diversity. Discriminating between different SNPs provides an enormous leap towards the better understanding of the uniqueness of biological systems. Here we report on a new approach for SNP discrimination using toehold-mediated DNA strand displacement. The distinctiveness of the approach is based on the combination of both 3- and 4-way branch migration mechanisms, which allows for reliable discrimination of SNPs within double-stranded DNA generated from real-life human mitochondrial DNA samples. Aside from the potential diagnostic value, the current study represents an additional way to control the strand displacement reaction rate without altering other reaction parameters and provides new insights into the influence of single nucleotide substitutions on 3- and 4-way branch migration efficiency and kinetics.

  20. Strand bias in complementary single-nucleotide polymorphisms of transcribed human sequences: evidence for functional effects of synonymous polymorphisms

    Directory of Open Access Journals (Sweden)

    Majewski Jacek

    2006-08-01

    Full Text Available Abstract Background Complementary single-nucleotide polymorphisms (SNPs may not be distributed equally between two DNA strands if the strands are functionally distinct, such as in transcribed genes. In introns, an excess of A↔G over the complementary C↔T substitutions had previously been found and attributed to transcription-coupled repair (TCR, demonstrating the valuable functional clues that can be obtained by studying such asymmetry. Here we studied asymmetry of human synonymous SNPs (sSNPs in the fourfold degenerate (FFD sites as compared to intronic SNPs (iSNPs. Results The identities of the ancestral bases and the direction of mutations were inferred from human-chimpanzee genomic alignment. After correction for background nucleotide composition, excess of A→G over the complementary T→C polymorphisms, which was observed previously and can be explained by TCR, was confirmed in FFD SNPs and iSNPs. However, when SNPs were separately examined according to whether they mapped to a CpG dinucleotide or not, an excess of C→T over G→A polymorphisms was found in non-CpG site FFD SNPs but was absent from iSNPs and CpG site FFD SNPs. Conclusion The genome-wide discrepancy of human FFD SNPs provides novel evidence for widespread selective pressure due to functional effects of sSNPs. The similar asymmetry pattern of FFD SNPs and iSNPs that map to a CpG can be explained by transcription-coupled mechanisms, including TCR and transcription-coupled mutation. Because of the hypermutability of CpG sites, more CpG site FFD SNPs are relatively younger and have confronted less selection effect than non-CpG FFD SNPs, which can explain the asymmetric discrepancy of CpG site FFD SNPs vs. non-CpG site FFD SNPs.

  1. Neocortical synaptophysin asymmetry and behavioral lateralization in chimpanzees (Pan troglodytes)

    DEFF Research Database (Denmark)

    Sherwood, Chet C; Duka, Tetyana; Stimpson, Cheryl D

    2010-01-01

    Although behavioral lateralization is known to correlate with certain aspects of brain asymmetry in primates, there are limited data concerning hemispheric biases in the microstructure of the neocortex. In the present study, we investigated whether there is asymmetry in synaptophysin-immunoreacti......Although behavioral lateralization is known to correlate with certain aspects of brain asymmetry in primates, there are limited data concerning hemispheric biases in the microstructure of the neocortex. In the present study, we investigated whether there is asymmetry in synaptophysin...... density. In contrast, puncta densities were symmetrical in right-handed chimpanzees. These findings support the conclusion that synapse asymmetry is modulated by lateralization of skilled motor behavior in chimpanzees....

  2. Three-dimensional assessment of facial asymmetry: A systematic review.

    Science.gov (United States)

    Akhil, Gopi; Senthil Kumar, Kullampalayam Palanisamy; Raja, Subramani; Janardhanan, Kumaresan

    2015-08-01

    For patients with facial asymmetry, complete and precise diagnosis, and surgical treatments to correct the underlying cause of the asymmetry are significant. Conventional diagnostic radiographs (submento-vertex projections, posteroanterior radiography) have limitations in asymmetry diagnosis due to two-dimensional assessments of three-dimensional (3D) images. The advent of 3D images has greatly reduced the magnification and projection errors that are common in conventional radiographs making it as a precise diagnostic aid for assessment of facial asymmetry. Thus, this article attempts to review the newly introduced 3D tools in the diagnosis of more complex facial asymmetries.

  3. Sagittal otolith morphogenesis asymmetry in marine fishes.

    Science.gov (United States)

    Mille, T; Mahe, K; Villanueva, M C; De Pontual, H; Ernande, B

    2015-09-01

    This study investigated and compared asymmetry in sagittal otolith shape and length between left and right inner ears in four roundfish and four flatfish species of commercial interest. For each species, the effects of ontogenetic changes (individual age and total body length), sexual dimorphism (individual sex) and the otolith's location on the right or left side of the head, on the shape and length of paired otoliths (between 143 and 702 pairs according to species) were evaluated. Ontogenetic changes in otolith shape and length were observed for all species. Sexual dimorphism, either in otolith shape and length or in their ontogenetic changes, was detected for half of the species, be they round or flat. Significant directional asymmetry in otolith shape and length was detected in one roundfish species each, but its inconsistency across species and its small average amplitude (6·17% for shape and 1·99% for length) suggested that it has barely any biological relevance. Significant directional asymmetry in otolith shape and length was found for all flatfish species except otolith length for one species. Its average amplitude varied between 2·06 and 17·50% for shape and between 0·00 and 11·83% for length and increased significantly throughout ontogeny for two species, one dextral and one sinistral. The longer (length) and rounder otolith (shape) appeared to be always on the blind side whatever the species. These results suggest differential biomineralization between the blind and ocular inner ears in flatfish species that could result from perturbations of the proximal-distal gradient of otolith precursors in the endolymph and the otolith position relative to the geometry of the saccular epithelium due to body morphology asymmetry and lateralized behaviour. The fact that asymmetry never exceeded 18% even at the individual level suggests an evolutionary canalization of otolith shape symmetry to avoid negative effects on fish hearing and balance. Technically

  4. Predictions of the poloidal asymmetries and transport frequencies in KSTAR

    Energy Technology Data Exchange (ETDEWEB)

    Bae, C., E-mail: cbae@nfri.re.kr; Lee, S. G.; Terzolo, L. [National Fusion Research Institute, Gwahak-ro, Yuseong-gu, Daejeon 305-806 (Korea, Republic of); Stacey, W. M. [Fusion Research Center, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States)

    2014-01-15

    The extended neoclassical rotation theory formulated in Miller flux surface geometry enables unprecedented neoclassical calculations of the poloidal asymmetries in density, rotation velocities, electrostatic potential along the flux surfaces, and of the inertial (Reynolds stress) and gyroviscous transport frequencies, which are strong functions of these asymmetries. This paper presents such calculations of the poloidal asymmetries and non-negligible inertial and gyroviscous transport frequencies in two KSTAR (Korea Superconducting Tokamak Advanced Research) [Kwon et al., Nucl. Fusion 51, 094006 (2011)] Neutral Beam Injection H-mode discharges. The in-out asymmetries in the velocities are an order of magnitude larger than their up-down asymmetries. The magnitudes of the predicted inertial and gyroviscous transport frequencies depend on the magnitudes of the density and velocity asymmetries. The neoclassically predicted density asymmetries are shown to correspond with the reported measurements in tokamaks and the predicted carbon toroidal velocities agree very well with the measurements in KSTAR.

  5. Interplay among transversity induced asymmetries in hadron leptoproduction

    CERN Document Server

    Adolph, C.; Alexeev, M.G.; Alexeev, G.D.; Amoroso, A.; Andrieux, V.; Anosov, V.; Augustyniak, W.; Austregesilo, A.; Azevedo, C.D.R.; Badelek, B.; Balestra, F.; Barth, J.; Beck, R.; Bedfer, Y.; Bernhard, J.; Bicker, K.; Bielert, E.R.; Birsa, R.; Bisplinghoff, J.; Bodlak, M.; Boer, M.; Bordalo, P.; Bradamante, F.; Braun, C.; Bressan, A.; Buchele, M.; Burtin, E.; Chang, W.C.; Chiosso, M.; Choi, I.; Chung, S.U.; Cicuttin, A.; Crespo, M.L.; Curiel, Q.; d'Hose, N.; Dalla Torre, S.; Dasgupta, S.S.; Dasgupta, S.; Denisov, O.Yu.; Dhara, L.; Donskov, S.V.; Doshita, N.; Duic, V.; Dziewiecki, M.; Efremov, A.; Elia, C.; Eversheim, P.D.; Eyrich, W.; Ferrero, A.; Finger, M.; M. Finger jr; Fischer, H.; Franco, C.; von Hohenesche, N. du Fresne; Friedrich, J.M.; Frolov, V.; Fuchey, E.; Gautheron, F.; Gavrichtchouk, O.P.; Gerassimov, S.; Giordano, F.; Gnesi, I.; Gorzellik, M.; Grabmuller, S.; Grasso, A.; Grosse-Perdekamp, M.; Grube, B.; Grussenmeyer, T.; Guskov, A.; Haas, F.; Hahne, D.; von Harrach, D.; Hashimoto, R.; Heinsius, F.H.; Herrmann, F.; Hinterberger, F.; Horikawa, N.; Hsieh, C.Yu; Huber, S.; Ishimoto, S.; Ivanov, A.; Ivanshin, Yu.; Iwata, T.; Jahn, R.; Jary, V.; Jorg, P.; Joosten, R.; Kabuss, E.; Ketzer, B.; Khaustov, G.V.; Khokhlov, Yu. A.; Kisselev, Yu.; Klein, F.; Klimaszewski, K.; Koivuniemi, J.H.; Kolosov, V.N.; Kondo, K.; Konigsmann, K.; Konorov, I.; Konstantinov, V.F.; Kotzinian, A.M.; Kouznetsov, O.; Kramer, M.; Kremser, P.; Krinner, F.; Kroumchtein, Z.V.; Kuchinski, N.; Kunne, F.; Kurek, K.; Kurjata, R.P.; Lednev, A.A.; Lehmann, A.; Levillain, M.; Levorato, S.; Lichtenstadt, J.; Longo, R.; Maggiora, A.; Magnon, A.; Makins, N.; Makke, N.; Mallot, G.K.; Marchand, C.; Marianski, B.; Martin, A.; Marzec, J.; Matousek, J.; Matsuda, H.; Matsuda, T.; Meshcheryakov, G.; Meyer, W.; Michigami, T.; Mikhailov, Yu. V.; Miyachi, Y.; Montuenga, P.; Nagaytsev, A.; Nerling, F.; Neyret, D.; Nikolaenko, V.I.; Novy, J.; Nowak, W.D.; Nukazuka, G.; Nunes, A.S.; Olshevsky, A.G.; Orlov, I.; Ostrick, M.; Panzieri, D.; Parsamyan, B.; Paul, S.; Peng, J.C.; Pereira, F.; Pesaro, G.; Pesek, M.; Peshekhonov, D.V.; Platchkov, S.; Pochodzalla, J.; Polyakov, V.A.; Pretz, J.; Quaresma, M.; Quintans, C.; Ramos, S.; Regali, C.; Reicherz, G.; Riedl, C.; Rossiyskaya, N.S.; Ryabchikov, D.I.; Rychter, A.; Samoylenko, V.D.; Sandacz, A.; Santos, C.; Sarkar, S.; Savin, I.A.; Sbrizzai, G.; Schiavon, P.; Schmidt, K.; Schmieden, H.; Schonning, K.; Schopferer, S.; Selyunin, A.; Shevchenko, O.Yu.; Silva, L.; Sinha, L.; Sirtl, S.; Slunecka, M.; Sozzi, F.; Srnka, A.; Stolarski, M.; Sulc, M.; Suzuki, H.; Szabelski, A.; Szameitat, T.; Sznajder, P.; Takekawa, S.; Wolbeek, J. ter; Tessaro, S.; Tessarotto, F.; Thibaud, F.; Tosello, F.; Tskhay, V.; Uhl, S.; Veloso, J.; Virius, M.; Weisrock, T.; Wilfert, M.; Zaremba, K.; Zavertyaev, M.; Zemlyanichkina, E.; Ziembicki, M.; Zink, A.

    2016-01-01

    In the fragmentation of a transversely polarized quark several left-right asymmetries are possible for the hadrons in the jet. When only one unpolarized hadron is selected, it exhibits an azimuthal modulation known as Collins effect. When a pair of oppositely charged hadrons is observed, three asymmetries can be considered, a di-hadron asymmetry and two single hadron asymmetries. In lepton deep inelastic scattering on transversely polarized nucleons all these asymmetries are coupled with the transversity distribution. From the high statistics COMPASS data on oppositely charged hadron-pair production we have investigated for the first time the dependence of these three asymmetries on the difference of the azimuthal angles of the two hadrons. The similarity of transversity induced single and di-hadron asymmetries is discussed. A phenomenological analysis of the data allows to establish quantitative relationships among them, providing strong indication that the underlying fragmentation mechanisms are all driven ...

  6. A hemispherical power asymmetry from inflation

    International Nuclear Information System (INIS)

    Erickcek, Adrienne L.; Kamionkowski, Marc; Carroll, Sean M.

    2008-01-01

    Measurements of cosmic microwave background temperature fluctuations by the Wilkinson Microwave Anisotropy Probe indicate that the fluctuation amplitude in one half of the sky differs from the amplitude in the other half. We show that such an asymmetry cannot be generated during single-field slow-roll inflation without violating constraints to the homogeneity of the Universe. In contrast, a multifield inflationary theory, the curvaton model, can produce this power asymmetry without violating the homogeneity constraint. The mechanism requires the introduction of a large-amplitude superhorizon perturbation to the curvaton field, possibly a preinflationary remnant or a superhorizon curvaton-web structure. The model makes several predictions, including non-Gaussianity and modifications to the inflationary consistency relation, that will be tested with forthcoming cosmic microwave background experiments.

  7. Labour market asymmetries in a monetary union

    DEFF Research Database (Denmark)

    Seneca, Martin; Andersen, Torben M.

    This paper takes a first step in analysing how a monetary union performs in the presence of labour market asymmetries. Differences in wage flexibility, market power and country sizes are allowed for in a setting with both countryspecific and aggregate shocks. The implications of asymmetries...... is not strictly increasing in nominal rigidities but hump-shaped. Moreover, a disproportionate share of the consequences of wage inflexibility may fall on small countries. In the case of country-specific shocks, a country unambiguously benefits in terms of macroeconomic stability by becoming more flexible, while...... this is not necessarily the case for aggregate shocks. There may thus be a tension between the degree of flexibility considered optimal at the country level and at the aggregate level within the monetary union....

  8. Quantum Correlations Evolution Asymmetry in Quantum Channels

    International Nuclear Information System (INIS)

    Li Meng; Huang Yun-Feng; Guo Guang-Can

    2017-01-01

    It was demonstrated that the entanglement evolution of a specially designed quantum state in the bistochastic channel is asymmetric. In this work, we generalize the study of the quantum correlations, including entanglement and quantum discord, evolution asymmetry to various quantum channels. We found that the asymmetry of entanglement and quantum discord only occurs in some special quantum channels, and the behavior of the entanglement evolution may be quite different from the behavior of the quantum discord evolution. To quantum entanglement, in some channels it decreases monotonously with the increase of the quantum channel intensity. In some other channels, when we increase the intensity of the quantum channel, it decreases at first, then keeps zero for some time, and then rises up. To quantum discord, the evolution becomes more complex and you may find that it evolutes unsmoothly at some points. These results illustrate the strong dependence of the quantum correlations evolution on the property of the quantum channels. (paper)

  9. Dark matter assimilation into the baryon asymmetry

    International Nuclear Information System (INIS)

    D'Eramo, Francesco; Fei, Lin; Thaler, Jesse

    2012-01-01

    Pure singlets are typically disfavored as dark matter candidates, since they generically have a thermal relic abundance larger than the observed value. In this paper, we propose a new dark matter mechanism called a ssimilation , which takes advantage of the baryon asymmetry of the universe to generate the correct relic abundance of singlet dark matter. Through assimilation, dark matter itself is efficiently destroyed, but dark matter number is stored in new quasi-stable heavy states which carry the baryon asymmetry. The subsequent annihilation and late-time decay of these heavy states yields (symmetric) dark matter as well as (asymmetric) standard model baryons. We study in detail the case of pure bino dark matter by augmenting the minimal supersymmetric standard model with vector-like chiral multiplets. In the parameter range where this mechanism is effective, the LHC can discover long-lived charged particles which were responsible for assimilating dark matter

  10. Lower limb asymmetry in mechanical muscle function

    DEFF Research Database (Denmark)

    Jordan, M J; Aagaard, Per; Herzog, W

    2015-01-01

    .05), and the final phase of the SJ (P AI in the CMJ concentric phase (r = 0.57, P Future research is required to assess the role of the CMJ and SJ phase-specific kinetic impulse AI......-R). Elite alpine skiers with ACL-R (n = 9; 26.2 ± 11.8 months post-op) and uninjured skiers (n = 9) participated in neuromuscular screening. Vertical ground reaction force during the CMJ and SJ was assessed using dual force plate methodology to obtain phase-specific bilateral asymmetry indices (AIs......) for kinetic impulse (CMJ and SJ phase-specific kinetic impulse AI). Dual x-ray absorptiometry scanning was used to assess asymmetry in lower body muscle mass. Compared with controls, ACL-R skiers had increased AI in muscle mass (P AI in the CMJ concentric phase (P 

  11. GDH Integral on the Proton from Asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Prok, Yelena [Univ. of Virginia, Charlottesville, VA (United States)

    2004-05-01

    Inclusive double spin electron asymmetries have been measured by scattering polarized electrons off the solid polarized 15NH3 target in Hall B of Jefferson Lab in 2000-2001. The virtual photon asymmetry A1 (x), the longitudinal spin structure function, g1 (x, Q2), and the first moment, γ1p, have been evaluated for a kinematic range of 0.05 ≥ Q2 ≥ 4.5 GeV2. The extracted results complement the existing data in the resonance region, extending it to lower and higher Q2 regions. The results are important in the study of Q2 evolution of nucleon structure from the hadronic to partonic degrees of freedom.

  12. Improving strand quality of upland oaks for use in oriented strand board

    Science.gov (United States)

    David B. DeValliance; Jody D. Gray; Shawn T. Grushecky

    2013-01-01

    Past research estimates that more than 1 million tons of oak logging residues go unused in West Virginia each year. Much research has been done investigating potential products and markets for this underutilized resource. West Virginia is home to an oriented strand board (OSB) producer that consumes large volumes of small diameter, low quality round wood. However, the...

  13. Five-Strand versus Four-Strand Hamstring Tendon Graft Technique for Anterior Cruciate Ligament Reconstruction: A Biomechanical Comparison.

    Science.gov (United States)

    Vaillant, Eric R; Parks, Brent G; Camire, Lyn M; Hinton, Richard Y

    2017-11-01

    The aim of this article is to compare diameter and stiffness, displacement, and strain in a five-strand versus four-strand hamstring graft for anterior cruciate ligament reconstruction. Eight matched pairs of lower extremities underwent four-strand or five-strand hamstring graft reconstruction. Diameter was significantly higher in the five-strand versus the four-strand construct ( p  = 0.002). No significant difference was found between the groups in construct displacement or stiffness. Significantly higher strain was observed in the inner limb versus the outer limb in the four-strand construct ( p  = 0.001) and in the inner limb versus the fifth limb in the 5-strand construct ( p  = 0.004). A fifth limb added to a four-strand hamstring graft significantly increased graft diameter but did not significantly change stiffness or displacement, suggesting that attachment of additional graft material via suture did not provide for full incorporation of the added limb into the graft at time zero. The inner limb in both constructs absorbed significantly greater load than did other limbs. The use of suture to attach additional material to a four-strand hamstring graft may not contribute to improved biomechanical qualities of the graft at time zero. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  14. W mass and W asymmetry at CDF

    International Nuclear Information System (INIS)

    Leone, S.

    1991-05-01

    The lepton charge asymmetry from W decaying into a lepton and a neutrino is discussed (preliminary result). This measurement gives information on parton distribution functions at low x values. The derivation of the recently published W mass value of 79.91 ± 0.39 GeV/c 2 is also presented. M W is used to set an upper limit on the top quark mass. 13 refs., 4 figs., 1 tab

  15. Relic neutrino asymmetry evolution from first principles

    International Nuclear Information System (INIS)

    Bell, N.F.; Volkas, R.R.; Wong, Y.Y.Y.

    1998-09-01

    The exact Quantum Kinetic Equations for a two-flavour active-sterile neutrino system are used to provide a systematic derivation of approximate evolution equations for the relic neutrino asymmetry. An extension of the adiabatic approximation for matter-affected neutrino oscillations is developed which incorporates decoherence due to collisions. Exact and approximate expressions for the decoherence and repopulation functions are discussed. A first pass is made over the exact treatment of multi-flavour partially incoherent oscillations. (authors)

  16. Charm production asymmetries at the Fermilab experiments

    International Nuclear Information System (INIS)

    Carter, T.

    1997-01-01

    I present asymmetries between the production of charm particles and anti-particles from Fermilab experiments, E687, E769 and E791. The results are shown as a function of x F and p t 2 for D ± and D s ± mesons and for pion, kaon and photon beams and compared against current models. Results are also shown for a recent analysis of correlations between production of charm mesons and an associated pion. 14 refs., 5 figs., 3 tabs

  17. Measurement of semileptonic asymmetries at LHCb

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    CP violation in neutral B meson mixing is an excellent place to search for the effects of new physics beyond the Standard Model. I report on the first measurements of the CP violating semileptonic asymmetries in the B_s0 and B_d0 systems from LHCb. Both are consistent with the Standard Model expectations and are the most precise single measurements of these parameters to date.

  18. [Lateralization of behavioral reactions and otolith asymmetry].

    Science.gov (United States)

    Lychakov, D V

    2013-01-01

    Lateralized behavior is widely spread among vertebrate animals and is determined first of ally by structural-functional brain asymmetry as well as by the presence of somatic and visceral asymmetry. Some kinds of asymmetric reactions are suggested to be due to the presence of asymmetry at the level of sense organs, in particular, of otolith organs. This review presents data on value and character of otolith asymmetry (OA) in animals of various species and classes, on action upon it of weightlessness and hypergravity; the problem of effect of OA on vestibular and auditory functions is considered. In symmetric vertebrates, OA has been shown to be of fluctuation character and its chi coefficient varies in diapason from -0.2 to 0.2; in the overwhelmed majority of individuals, /chi/ otolith organs to work coordinately; this it why OA is at the equally low level regardless of the individual's taxonomic and ecologic position, its size, age, and otolith growth rate. Individuals with abnormally high OA level can experience difficulties in analysis of auditory and vestibular stimuli, therefore in nature the majority of such individuals are eliminated in the process of natural selection. Unlike symmetrical vertebrates, labyrinths of many Pleuronectiformes have pronounced OA--otoliths of the lower labyrinth, on a average, are significantly heavier than those of the upper labyrinth. Their organs are the only example when OA with directed character seem to play an essential role in lateralized behavior and are suggested to be used in the spatial localization of the sound source. The short-time action of weightlessness and relatively weak hypergravity ( or = 3g, as well as some diseases and shifts connected with processes of aging can enhance OA and cause several functional disturbances.

  19. Hole hopping rates in single strand oligonucleotides

    Energy Technology Data Exchange (ETDEWEB)

    Borrelli, Raffaele [Dipartimento di Scienze Agrarie, Forestali e Alimentari, Università di Torino, Largo Paolo Braccini 2, I-10095 Grugliasco, TO (Italy); Capobianco, Amedeo [Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II, I-84084 Fisciano, SA (Italy); Peluso, Andrea, E-mail: apeluso@unisa.it [Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II, I-84084 Fisciano, SA (Italy)

    2014-08-31

    Highlights: • DNA hole transfer rates have been computed. • Delocalized adenine domains significantly affect hole transfer rates in DNA. • Franck–Condon weighted density of state from DFT normal modes. • DNA application in molecular electronics. - Abstract: The rates of hole transfer between guanine and adenine in single strand DNA have been evaluated by using Fermi’s golden rule and Kubo’s generating function approach for the Franck–Condon weighted density of states. The whole sets of the normal modes and vibrational frequencies of the two nucleobases, obtained at DFT/B3LYP level of calculation, have been considered in computations. The results show that in single strand the pyramidalization/planarization mode of the amino groups of both nucleobases plays the major role. At room temperature, the Franck–Condon density of states extends over a wide range of hole site energy difference, 0–1 eV, giving some hints about the design of oligonucleotides of potential technological interest.

  20. Esthetic evaluation of dental and gingival asymmetries.

    Science.gov (United States)

    Fernandes, Liliana; Pinho, Teresa

    2015-06-01

    The aim of this study was to determine which smile asymmetries were less esthetic, dental or gingival. Laypeople (297), generalists (223), prosthodontists (50) and orthodontists (49), evaluated the esthetics of digitally-modified images taken from the same frontal intra-oral photograph, using the same lips, simulating upper maxillary midline shift, occlusal plane inclination, asymmetric incisal edge and asymmetric gingival migration. The images were later paired into 3 groups. The only ones considered esthetic were the asymmetric incisal edge of the 0.5 mm shorter upper central incisor and the asymmetric gingival migration (2 mm) of the upper central incisor. In the paired images, upper maxillary midline shift vs. occlusal plane inclination, the former was rated less esthetic, while in the asymmetric incisal edge vs. asymmetric gingival migration pair, the latter was considered to be less esthetic. Laypeople and generalists consider smiles more attractive. The only images considered esthetic were the asymmetric incisal edge of the central incisor shorter by 0.5 mm and the 2 mm asymmetric gingival migration of the upper central incisor. In the horizontal plane (maxillary midline shift vs. occlusal plane cant), the dental asymmetries were considered less esthetic than the gingival asymmetries. However, in the vertical plane (asymmetric incisal edge vs. asymmetric gingival migration) the opposite was recorded. Copyright © 2015 CEO. Published by Elsevier Masson SAS. All rights reserved.

  1. Frontal Brain Asymmetry and Willingness to Pay

    Directory of Open Access Journals (Sweden)

    Thomas Z. Ramsøy

    2018-03-01

    Full Text Available Consumers frequently make decisions about how much they are willing to pay (WTP for specific products and services, but little is known about the neural mechanisms underlying such calculations. In this study, we were interested in testing whether specific brain activation—the asymmetry in engagement of the prefrontal cortex—would be related to consumer choice. Subjects saw products and subsequently decided how much they were willing to pay for each product, while undergoing neuroimaging using electroencephalography. Our results demonstrate that prefrontal asymmetry in the gamma frequency band, and a trend in the beta frequency band that was recorded during product viewing was significantly related to subsequent WTP responses. Frontal asymmetry in the alpha band was not related to WTP decisions. Besides suggesting separate neuropsychological mechanisms of consumer choice, we find that one specific measure—the prefrontal gamma asymmetry—was most strongly related to WTP responses, and was most coupled to the actual decision phase. These findings are discussed in light of the psychology of WTP calculations, and in relation to the recent emergence of consumer neuroscience and neuromarketing.

  2. L-R asymmetry in gut's

    International Nuclear Information System (INIS)

    Karadayi, H.R.

    1982-01-01

    An idea of L-R asymmetry is proposed for the grand unification schemes. The idea provides an intrinsic mechanism to obtain standard model charges of fermions in the case of more than one weak gauge boson. It is elaborated within a scheme based on the partial symmetry SU(4)sub(C)xSU(2)sub(L)xSU(2)sub(R) where the coupling constants gsub(L) and gsub(R) corresponding to the chiral SU(2) factors are assumed to be different from each other. Then, the embedding of this structure within the simple symmetry SO(10) is shown. In both cases, a consistent description of vector particle masses is given. These two schemes are considered as primary models to realize the L-R asymmetry idea due to the lack of family unification. However, in a subsequent work, we will show that the SO(14) unification of the three families can be obtained within the framework of L-R asymmetry. All formulations are carried out with the aid of a mathematical method that we recently proposed for the Lie algebra representations of classical groups. (author)

  3. Frontal Brain Asymmetry and Willingness to Pay

    Science.gov (United States)

    Ramsøy, Thomas Z.; Skov, Martin; Christensen, Maiken K.; Stahlhut, Carsten

    2018-01-01

    Consumers frequently make decisions about how much they are willing to pay (WTP) for specific products and services, but little is known about the neural mechanisms underlying such calculations. In this study, we were interested in testing whether specific brain activation—the asymmetry in engagement of the prefrontal cortex—would be related to consumer choice. Subjects saw products and subsequently decided how much they were willing to pay for each product, while undergoing neuroimaging using electroencephalography. Our results demonstrate that prefrontal asymmetry in the gamma frequency band, and a trend in the beta frequency band that was recorded during product viewing was significantly related to subsequent WTP responses. Frontal asymmetry in the alpha band was not related to WTP decisions. Besides suggesting separate neuropsychological mechanisms of consumer choice, we find that one specific measure—the prefrontal gamma asymmetry—was most strongly related to WTP responses, and was most coupled to the actual decision phase. These findings are discussed in light of the psychology of WTP calculations, and in relation to the recent emergence of consumer neuroscience and neuromarketing. PMID:29662432

  4. Structural connectivity asymmetry in the neonatal brain.

    Science.gov (United States)

    Ratnarajah, Nagulan; Rifkin-Graboi, Anne; Fortier, Marielle V; Chong, Yap Seng; Kwek, Kenneth; Saw, Seang-Mei; Godfrey, Keith M; Gluckman, Peter D; Meaney, Michael J; Qiu, Anqi

    2013-07-15

    Asymmetry of the neonatal brain is not yet understood at the level of structural connectivity. We utilized DTI deterministic tractography and structural network analysis based on graph theory to determine the pattern of structural connectivity asymmetry in 124 normal neonates. We tracted white matter axonal pathways characterizing interregional connections among brain regions and inferred asymmetry in left and right anatomical network properties. Our findings revealed that in neonates, small-world characteristics were exhibited, but did not differ between the two hemispheres, suggesting that neighboring brain regions connect tightly with each other, and that one region is only a few paths away from any other region within each hemisphere. Moreover, the neonatal brain showed greater structural efficiency in the left hemisphere than that in the right. In neonates, brain regions involved in motor, language, and memory functions play crucial roles in efficient communication in the left hemisphere, while brain regions involved in emotional processes play crucial roles in efficient communication in the right hemisphere. These findings suggest that even at birth, the topology of each cerebral hemisphere is organized in an efficient and compact manner that maps onto asymmetric functional specializations seen in adults, implying lateralized brain functions in infancy. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Dichotic listening in patients with situs inversus: brain asymmetry and situs asymmetry.

    Science.gov (United States)

    Tanaka, S; Kanzaki, R; Yoshibayashi, M; Kamiya, T; Sugishita, M

    1999-06-01

    In order to investigate the relation between situs asymmetry and functional asymmetry of the human brain, a consonant-vowel syllable dichotic listening test known as the Standard Dichotic Listening Test (SDLT) was administered to nine subjects with situs inversus (SI) that ranged in age from 6 to 46 years old (mean of 21.8 years old, S.D. = 15.6); the four males and five females all exhibited strong right-handedness. The SDLT was also used to study twenty four age-matched normal subjects that were from 6 to 48 years old (mean 21.7 years old, S.D. = 15.3); the twelve males and twelve females were all strongly right-handed and served as a control group. Eight out of the nine subjects (88.9%) with SI more often reproduced the sounds from the right ear than sounds from the left ear; this is called right ear advantage (REA). The ratio of REA in the control group was almost the same, i.e., nineteen out of the twenty-four subjects (79.1%) showed REA. Results of the present study suggest that the left-right reversal in situs inversus does not involve functional asymmetry of the brain. As such, the system that produces functional asymmetry in the human brain must independently recognize laterality from situs asymmetry.

  6. Stranded cost recovery in electricity market reforms in the US

    International Nuclear Information System (INIS)

    Woo, C.K.; Lloyd, D.; Karimov, R.; Tishler, A.

    2003-01-01

    An important element of an electricity market reform is stranded cost recovery. This paper explains the cause of stranded costs, describes four recovery mechanisms, evaluates these mechanisms using the criteria of recovery certainty, economic efficiency and equity, reviews the financial performance of 12 utilities in the US in connection to stranded cost recovery, and shows why the mechanism used in California has contributed to the reform failure in that state. (Author)

  7. Asymmetry Assessment Using Surface Topography in Healthy Adolescents

    Directory of Open Access Journals (Sweden)

    Connie Ho

    2015-08-01

    Full Text Available The ability to assess geometric asymmetry in the torsos of individuals is important for detecting Adolescent Idiopathic Scoliosis (AIS. A markerless technique using Surface Topography (ST has been introduced as a non-invasive alternative to standard diagnostic radiographs. The technique has been used to identify asymmetry patterns associated with AIS. However, the presence and nature of asymmetries in the healthy population has not been properly studied. The purpose of this study is therefore to identify asymmetries and potential relationships to development factors such as age, gender, hand dominance and unilateral physical activity in healthy adolescents. Full torso scans of 83 participants were analyzed. Using Geomagic, deviation contour maps (DCMs were created by reflecting the torso along the best plane of sagittal symmetry with each spectrum normalized. Two classes of asymmetry were observed: twist and thickness each with subgroupings. Averaged interobserver and intraobserver Kappas for twist subgroupings were 0.84 and 0.84, respectively, and for thickness subgroupings were 0.53 and 0.63 respectively. Further significant relationships were observed between specific types of asymmetry and gender such as females displaying predominately twist asymmetry, and males with thickness asymmetry. However, no relationships were found between type of asymmetry and age, hand dominance or unilateral physical activity. Understanding asymmetries in healthy subjects will continue to enhance assessment ability of the markerless ST technique.

  8. Theoretical analysis on ac loss properties of two-strand parallel conductors composed of superconducting multifilamentary strands

    CERN Document Server

    Iwakuma, M; Funaki, K

    2002-01-01

    The ac loss properties of two-strand parallel conductors composed of superconducting multifilamentary strands were theoretically investigated. The constituent strands generally need to be insulated and transposed for the sake of uniform current distribution and low ac loss. In case the transposition points deviate from the optimum ones, shielding current is induced according to the interlinkage magnetic flux of the twisted loop enclosed by the insulated strands and the contact resistances at the terminals. It produces an additional ac loss. Supposing a simple situation where a two-strand parallel conductor with one-point transposition is exposed to a uniform ac magnetic field, the basic equations for the magnetic field were proposed and the theoretical expressions of the additional ac losses derived. As a result, the following features were shown. The additional ac loss in the non-saturation case, where the induced shielding current is less than the critical current of a strand, is proportional to the square ...

  9. Signs of Asymmetry in Exploding Stars

    Science.gov (United States)

    Hensley, Kerry

    2018-03-01

    Supernova explosions enrich the interstellar medium and can even briefly outshine their host galaxies. However, the mechanism behind these massive explosions still isnt fully understood. Could probing the asymmetry of supernova remnants help us better understand what drives these explosions?Hubble image of the remnant of supernova 1987A, one of the first remnants discovered to be asymmetrical. [ESA/Hubble, NASA]Stellar Send-OffsHigh-mass stars end their lives spectacularly. Each supernova explosion churns the interstellar medium and unleashes high-energy radiation and swarms of neutrinos. Supernovae also suffuse the surrounding interstellar medium with heavy elements that are incorporated into later generations of stars and the planets that form around them.The bubbles of expanding gas these explosions leave behind often appear roughly spherical, but mounting evidence suggests that many supernova remnants are asymmetrical. While asymmetry in supernova remnants can arise when the expanding material plows into the non-uniform interstellar medium, it can also be an intrinsic feature of the explosion itself.Simulation results clockwise from top left: Mass density, calcium mass fraction, oxygen mass fraction, nickel-56 mass fraction. Click to enlarge. [Adapted from Wollaeger et al. 2017]Coding ExplosionsThe presence or absence of asymmetry in a supernova remnant can hold clues as to what drove the explosion. But how can we best observe asymmetry in a supernova remnant? Modeling lets us explore different observational approaches.A team of scientists led by Ryan T. Wollaeger (Los Alamos National Laboratory) used radiative transfer and radiative hydrodynamics simulations to model the explosion of a core-collapse supernova. Wollaeger and collaborators introduced asymmetry into the explosion by creating a single-lobed, fast-moving outflow along one axis.Their simulations showed that while some chemical elements lingered near the origin of the explosion or were distributed

  10. A methodology to identify stranded generation facilities and estimate stranded costs for Louisiana's electric utility industry

    Science.gov (United States)

    Cope, Robert Frank, III

    1998-12-01

    The electric utility industry in the United States is currently experiencing a new and different type of growing pain. It is the pain of having to restructure itself into a competitive business. Many industry experts are trying to explain how the nation as a whole, as well as individual states, will implement restructuring and handle its numerous "transition problems." One significant transition problem for federal and state regulators rests with determining a utility's stranded costs. Stranded generation facilities are assets which would be uneconomic in a competitive environment or costs for assets whose regulated book value is greater than market value. At issue is the methodology which will be used to estimate stranded costs. The two primary methods are known as "Top-Down" and "Bottom-Up." The "Top-Down" approach simply determines the present value of the losses in revenue as the market price for electricity changes over a period of time into the future. The problem with this approach is that it does not take into account technical issues associated with the generation and wheeling of electricity. The "Bottom-Up" approach computes the present value of specific strandable generation facilities and compares the resulting valuations with their historical costs. It is regarded as a detailed and difficult, but more precise, approach to identifying stranded assets and their associated costs. This dissertation develops a "Bottom-Up" quantitative, optimization-based approach to electric power wheeling within the state of Louisiana. It optimally evaluates all production capabilities and coordinates the movement of bulk power through transmission interconnections of competing companies in and around the state. Sensitivity analysis to this approach is performed by varying seasonal consumer demand, electric power imports, and transmission inter-connection cost parameters. Generation facility economic dispatch and transmission interconnection bulk power transfers, specific

  11. Excess single-stranded DNA inhibits meiotic double-strand break repair.

    Directory of Open Access Journals (Sweden)

    Rebecca Johnson

    2007-11-01

    Full Text Available During meiosis, self-inflicted DNA double-strand breaks (DSBs are created by the protein Spo11 and repaired by homologous recombination leading to gene conversions and crossovers. Crossover formation is vital for the segregation of homologous chromosomes during the first meiotic division and requires the RecA orthologue, Dmc1. We analyzed repair during meiosis of site-specific DSBs created by another nuclease, VMA1-derived endonuclease (VDE, in cells lacking Dmc1 strand-exchange protein. Turnover and resection of the VDE-DSBs was assessed in two different reporter cassettes that can repair using flanking direct repeat sequences, thereby obviating the need for a Dmc1-dependent DNA strand invasion step. Access of the single-strand binding complex replication protein A, which is normally used in all modes of DSB repair, was checked in chromatin immunoprecipitation experiments, using antibody against Rfa1. Repair of the VDE-DSBs was severely inhibited in dmc1Delta cells, a defect that was associated with a reduction in the long tract resection required to initiate single-strand annealing between the flanking repeat sequences. Mutants that either reduce Spo11-DSB formation or abolish resection at Spo11-DSBs rescued the repair block. We also found that a replication protein A component, Rfa1, does not accumulate to expected levels at unrepaired single-stranded DNA (ssDNA in dmc1Delta cells. The requirement of Dmc1 for VDE-DSB repair using flanking repeats appears to be caused by the accumulation of large quantities of ssDNA that accumulate at Spo11-DSBs when Dmc1 is absent. We propose that these resected DSBs sequester both resection machinery and ssDNA binding proteins, which in wild-type cells would normally be recycled as Spo11-DSBs repair. The implication is that repair proteins are in limited supply, and this could reflect an underlying mechanism for regulating DSB repair in wild-type cells, providing protection from potentially harmful effects

  12. Strand Plasticity Governs Fatigue in Colloidal Gels

    Science.gov (United States)

    van Doorn, Jan Maarten; Verweij, Joanne E.; Sprakel, Joris; van der Gucht, Jasper

    2018-05-01

    The repeated loading of a solid leads to microstructural damage that ultimately results in catastrophic material failure. While posing a major threat to the stability of virtually all materials, the microscopic origins of fatigue, especially for soft solids, remain elusive. Here we explore fatigue in colloidal gels as prototypical inhomogeneous soft solids by combining experiments and computer simulations. Our results reveal how mechanical loading leads to irreversible strand stretching, which builds slack into the network that softens the solid at small strains and causes strain hardening at larger deformations. We thus find that microscopic plasticity governs fatigue at much larger scales. This gives rise to a new picture of fatigue in soft thermal solids and calls for new theoretical descriptions of soft gel mechanics in which local plasticity is taken into account.

  13. Subcycle dynamics of Coulomb asymmetry in strong elliptical laser fields.

    Science.gov (United States)

    Li, Min; Liu, Yunquan; Liu, Hong; Ning, Qicheng; Fu, Libin; Liu, Jie; Deng, Yongkai; Wu, Chengyin; Peng, Liang-You; Peng, Liangyou; Gong, Qihuang

    2013-07-12

    We measure photoelectron angular distributions of noble gases in intense elliptically polarized laser fields, which indicate strong structure-dependent Coulomb asymmetry. Using a dedicated semiclassical model, we have disentangled the contribution of direct ionization and multiple forward scattering on Coulomb asymmetry in elliptical laser fields. Our theory quantifies the roles of the ionic potential and initial transverse momentum on Coulomb asymmetry, proving that the small lobes of asymmetry are induced by direct ionization and the strong asymmetry is induced by multiple forward scattering in the ionic potential. Both processes are distorted by the Coulomb force acting on the electrons after tunneling. Lowering the ionization potential, the relative contribution of direct ionization on Coulomb asymmetry substantially decreases and Coulomb focusing on multiple rescattering is more important. We do not observe evident initial longitudinal momentum spread at the tunnel exit according to our simulation.

  14. Relationship between information asymmetry and cost of capital

    Directory of Open Access Journals (Sweden)

    Fateme Rahmani

    2013-01-01

    Full Text Available Shareholders expected return is normally impacted by informational risk and informational asymmetry, on the other hand, creates informational risk. Thus, investors demand greater risk premium in the case of informational asymmetry and in turn corporate expenditures increase. In this study, we determine the relationship between informational asymmetry and capital cost. The study uses information of 109 companies listed in Tehran Securities Exchange over the period of 2005-2010 and the results suggest a positive and significant relationship between informational asymmetry and capital cost. In addition, the results from present research indicate that when capital markets are competitive, there is not a significant relationship between informational asymmetry and capital cost. But when markets are partially competitive there is a significant relationship between informational asymmetry and capital cost.

  15. Stranding of two sperm whales (Physeter macrocephalus) in the "North Sea trap" at Henne Strand, Denmark

    DEFF Research Database (Denmark)

    Hansen, Mette Sif; Alstrup, Aage K. O.; Hansen, Jørgen H.

    2016-01-01

    In February 2014 two male sperm whales (Physeter macrocephalus) stranded at Henne Strand, Denmark. One whale (MCE 1644) was found dead, while the other (MCE 1645) was still alive, but drowned during the high tide. To increase our knowledge of sperm whales, conduct forage investigations, post......-mortem and diagnostic examinations were carried out. The decay of the carcasses progressed quickly. The whales had large (MCE 1644) or moderate (MCE 1645) numbers of squid beaks (Gonatus fabricii) in the stomachventricles, but no evidence of recentfresh feeding. Both whales had acute dermatitis probably due to trauma...... severe localized or systemic infections. The finding of large volumes of bloody pleural fluid with large quantities of C. septicum suggests that MCE 1644 died of infection. However, reservations must be taken due to the pronounced decay of the carcass. Sperm whales have strong social bonds where...

  16. Rare decays and CP asymmetries in charged B decays

    International Nuclear Information System (INIS)

    Deshpande, N.G.

    1991-01-01

    The theory of loop induced rare decays and the rate asymmetry due to CP violation in charged B Decays in reviewed. After considering b → sγ and b → se + e - decays, the asymmetries for pure penguin process are estimated first. A larger asymmetry can result in those modes where a tree diagram and a penguin diagram interfere, however these estimates are necessarily model dependent. Estimates of Cabbibo suppressed penguins are also considered

  17. Asymmetries in heavy meson production from light quark fragmentation

    International Nuclear Information System (INIS)

    Dias de Deus, J.; Duraes, F.

    2000-01-01

    We discuss the possibility of the asymmetry in D - /D + production from π - beams, being a direct consequence of the properties of the light quark fragmentation function into heavy mesons. The main features of the asymmetry, as a function of x F , are easily described. An integrated sum rule for the D - , D + multiplicity difference is presented. Predictions for the asymmetry in B meson production are given. (orig.)

  18. Protected DNA strand displacement for enhanced single nucleotide discrimination in double-stranded DNA

    OpenAIRE

    Khodakov, Dmitriy A.; Khodakova, Anastasia S.; Huang, David M.; Linacre, Adrian; Ellis, Amanda V.

    2015-01-01

    Single nucleotide polymorphisms (SNPs) are a prime source of genetic diversity. Discriminating between different SNPs provides an enormous leap towards the better understanding of the uniqueness of biological systems. Here we report on a new approach for SNP discrimination using toehold-mediated DNA strand displacement. The distinctiveness of the approach is based on the combination of both 3- and 4-way branch migration mechanisms, which allows for reliable discrimination of SNPs within doubl...

  19. Contract Design: The problem of information asymmetry.

    Science.gov (United States)

    Mühlbacher, Axel C; Amelung, Volker E; Juhnke, Christin

    2018-01-12

    Integrated care systems are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. Little is known about the contractual design and the main challenges of delegating "accountability" to these new kinds of organisations and/or contracts. The research question in this article focuses on how healthcare contracts can look like and which possible problems arise in designing such contracts. In this a special interest is placed on information asymmetries. A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. This article is the first in a row of three that all contribute to a specific issue in designing healthcare contracts. Starting with the organisation of contracts and information asymmetries, part 2 focusses on financial options and risks and part 3 finally concludes with the question of risk management and evaluation. Healthcare contracting between providers and payers will have a major impact on the overall design of future healthcare systems. If Integrated care systems or any other similar concept of care delivery are to be contracted directly by payers to manage the continuum of care the costs of market utilisation play an essential role. Transaction costs also arise in the course of the negotiation and implementation of contracts. These costs are the reason why it is generally not possible to conclude perfect (complete) contracts. Problems with asymmetric distribution of information can relate to the situation before a contract is concluded (adverse selection) and after conclusion of a contract (moral hazard). Information asymmetries are seen as a major obstacle to the efficient operation of integrated care programmes. Coordination and motivation problems cannot be solved at no-costs. The presented problems in the design of selective individual contracts

  20. Symmetry and Asymmetry in Bouncing Gaits

    Directory of Open Access Journals (Sweden)

    Giovanni A. Cavagna

    2010-06-01

    Full Text Available In running, hopping and trotting gaits, the center of mass of the body oscillates each step below and above an equilibrium position where the vertical force on the ground equals body weight. In trotting and low speed human running, the average vertical acceleration of the center of mass during the lower part of the oscillation equals that of the upper part, the duration of the lower part equals that of the upper part and the step frequency equals the resonant frequency of the bouncing system: we define this as on-offground symmetric rebound. In hopping and high speed human running, the average vertical acceleration of the center of mass during the lower part of the oscillation exceeds that of the upper part, the duration of the upper part exceeds that of the lower part and the step frequency is lower than the resonant frequency of the bouncing system: we define this as on-off-ground asymmetric rebound. Here we examine the physical and physiological constraints resulting in this on-off-ground symmetry and asymmetry of the rebound. Furthermore, the average force exerted during the brake when the body decelerates downwards and forwards is greater than that exerted during the push when the body is reaccelerated upwards and forwards. This landing-takeoff asymmetry, which would be nil in the elastic rebound of the symmetric spring-mass model for running and hopping, suggests a less efficient elastic energy storage and recovery during the bouncing step. During hopping, running and trotting the landing-takeoff asymmetry and the mass-specific vertical stiffness are smaller in larger animals than in the smaller animals suggesting a more efficient rebound in larger animals.

  1. Second-strand cDNA synthesis: classical method

    International Nuclear Information System (INIS)

    Gubler, U.

    1987-01-01

    The classical scheme for the synthesis of double-stranded cDNA as it was reported in 1976 is described. Reverse transcription of mRNA with oligo(dT) as the primer generates first strands with a small loop at the 3' end of the cDNA (the end that corresponds to the 5' end of the mRNA). Subsequent removal of the mRNA by alkaline hydrolysis leaves single-stranded cDNA molecules again with a small 3' loop. This loop can be used by either reverse transcriptase or Klenow fragment of DNA polymerase I as a primer for second-strand synthesis. The resulting products are double-stranded cDNA molecules that are covalently closed at the end corresponding to the 5' end of the original mRNA. Subsequent cleavage of the short piece of single-stranded cDNA within the loop with the single-strand-specific S 1 nuclease generate open double-stranded molecules that can be used for molecular cloning in plasmids or in phage. Useful variations of this scheme have been described

  2. Getting Frustrated: Modelling Emotion Contagion in Stranded Passengers

    NARCIS (Netherlands)

    van der Wal, C. Natalie; Couwenberg, Maik; Bosse, T.

    2017-01-01

    Train passengers can get stranded due to a variety of events, such as a delay, technical malfunctioning or a natural disaster. Stranded passengers can get frustrated, which could escalate in misbehaviours. Examples are verbal and physical violence or dangerous behaviours such as opening emergency

  3. Cetacean strandings along the coast of Izmir Bay, Turkey

    NARCIS (Netherlands)

    Guclusoy, H.; Veryeri, N.; Cirik, S.

    2004-01-01

    The present paper provides information on the stranding of cetaceans in Izmir Bay, Aegean Sea, between 1992 and 2004. The data were collected opportunistically during sightings and stranding data collection for Monk Seals. A total of 12 cetaceans, namely Bottle-nosed Dolphin, Tursiops truncatus

  4. Structural features of single-stranded integron cassette attC sites and their role in strand selection.

    Directory of Open Access Journals (Sweden)

    Marie Bouvier

    2009-09-01

    Full Text Available We recently showed that cassette integration and deletion in integron platforms were occurring through unconventional site-specific recombination reactions involving only the bottom strand of attC sites. The lack of sequence conservation among attC sites led us to hypothesize that sequence-independent structural recognition determinants must exist within attC sites. The structural data obtained from a synaptic complex of the Vibrio cholerae integrase with the bottom strand of an attC site has shown the importance of extra helical bases (EHB inside the stem-loop structure formed from the bottom strand. Here, we systematically determined the contribution of three structural elements common to all known single-stranded attC site recombination substrates (the EHBs, the unpaired central spacer (UCS, and the variable terminal structure (VTS to strand choice and recombination. Their roles have been evaluated in vivo in the attIxattC reaction context using the suicide conjugation assay we previously developed, but also in an attCxattC reaction using a deletion assay. Conjugation was used to deliver the attC sites in single-stranded form. Our results show that strand choice is primarily directed by the first EHB, but the presence of the two other EHBs also serves to increase this strand selection. We found that the structure of the central spacer is essential to achieve high level recombination of the bottom strand, suggesting a dual role for this structure in active site exclusion and for hindering the reverse reaction after the first strand exchange. Moreover, we have shown that the VTS has apparently no role in strand selectivity.

  5. Intraday market asymmetries — A Nordic example

    DEFF Research Database (Denmark)

    Soysal, Emilie Rosenlund; Olsen, Ole Jess; Skytte, Klaus

    2017-01-01

    , particularly important for VRE producers, but it also means that the price formation at intraday market can change optimal bidding strategy in the day-ahead market. Through econometric modelling of intraday price premiums, this paper investigates intraday price asymmetries, which potentially can lead...... to strategic bidding. The intraday market is per definition symmetric, as prices for power sales always correspond to prices for power purchases, however, we find that this symmetry is not reflected in the price structure in regards to the total load adjustment needs....

  6. Top quark asymmetry and dijet resonances

    CERN Document Server

    Jung, Sunghoon; Wells, James D.

    2011-01-01

    CDF recently reported an anomaly in the $m_{jj}$ distribution of dijet events produced in association with a $W$ boson. If this anomaly is associated with a new flavor conserving vector resonance, $V$, one might have expected to observe effects in the analogous $m_{jj}$ distribution produced in association with a $\\gamma$. No such excess is observed. A single $u-t-V$ flavor changing coupling, however, can contribute to the $m_{jj}$ anomaly while being consistent with other resonance searches. Furthermore, it gives a potential explanation of the observed forward-backward asymmetry in top quark production.

  7. Origin of the matter-antimatter asymmetry

    International Nuclear Information System (INIS)

    Dine, Michael; Kusenko, Alexander

    2004-01-01

    Although the origin of matter-antimatter asymmetry remains unknown, continuing advances in theory and improved experimental limits have ruled out some scenarios for baryogenesis, for example, sphaleron baryogenesis at the electroweak phase transition in the Standard Model. At the same time, the success of cosmological inflation and the prospects for discovering supersymmetry at the Large Hadron Collider have put some other models in sharper focus. We review the current state of our understanding of baryogenesis with emphasis on those scenarios that we consider most plausible

  8. [Asymmetry of antennal grooming in the cockroach (Periplaneta americana)].

    Science.gov (United States)

    2014-07-01

    The present study was conducted to determine the key features of antennal grooming of male American cockroaches in neutral circumstances. It was shown for the first time that the right antenna was cleaned significantly more often than the left one, which indicates the presence of functional asymmetry of antennal grooming in this insect species. At the same time, no statistically significant asymmetry was found for grooming of antennal bases and legs. Morphological asymmetries of antennae and legs and/or brain lateralization are the plausible sources of observed behavioral asymmetry in antennal grooming.

  9. Experimental investigation of transverse spin asymmetries in muon-p SIDIS processes: Collins asymmetries

    CERN Document Server

    Adolph, C.; Alexakhin, V.Yu.; Alexandrov, Yu.; Alexeev, G.D.; Amoroso, A.; Antonov, A.A.; Austregesilo, A.; Badelek, B.; Balestra, F.; Barth, J.; Baum, G.; Bedfer, Y.; Bernhard, J.; Bertini, R.; Bettinelli, M.; Bicker, K.; Bieling, J.; Birsa, R.; Bisplinghoff, J.; Bordalo, P.; Bradamante, F.; Braun, C.; Bravar, A.; Bressan, A.; Burtin, E.; Capozza, L.; Chiosso, M.; Chung, S.U.; Cicuttin, A.; Crespo, M.L.; Dalla Torre, S.; Das, S.; Dasgupta, S.S.; Dasgupta, S.; Denisov, O.Yu.; Dhara, L.; Donskov, S.V.; Doshita, N.; Duic, V.; Dunnweber, W.; Dziewiecki, M.; Efremov, A.; Elia, C.; Eversheim, P.D.; Eyrich, W.; Faessler, M.; Ferrero, A.; Filin, A.; Finger, M.; Fischer, H.; Franco, C.; von Hohenesche, N.du Fresne; Friedrich, J.M.; Frolov, V.; Garfagnini, R.; Gautheron, F.; Gavrichtchouk, O.P.; Gerassimov, S.; Geyer, R.; Giorgi, M.; Gnesi, I.; Gobbo, B.; Goertz, S.; Grabmuller, S.; Grasso, A.; Grube, B.; Gushterski, R.; Guskov, A.; Guthorl, T.; Haas, F.; von Harrach, D.; Heinsius, F.H.; Herrmann, F.; Hess, C.; Hinterberger, F.; Horikawa, N.; Hoppner, Ch.; d'Hose, N.; Ishimoto, S.; Ivanov, O.; Ivanshin, Yu.; Iwata, T.; Jahn, R.; Jary, V.; Jasinski, P.; Joosten, R.; Kabuss, E.; Kang, D.; Ketzer, B.; Khaustov, G.V.; Khokhlov, Yu.A.; Kisselev, Yu.; Klein, F.; Klimaszewski, K.; Koblitz, S.; Koivuniemi, J.H.; Kolosov, V.N.; Kondo, K.; Konigsmann, K.; Konorov, I.; Konstantinov, V.F.; Korzenev, A.; Kotzinian, A.M.; Kouznetsov, O.; Kramer, M.; Kroumchtein, Z.V.; Kunne, F.; Kurek, K.; Lauser, L.; Lednev, A.A.; Lehmann, A.; Levorato, S.; Lichtenstadt, J.; Liska, T.; Maggiora, A.; Magnon, A.; Makke, N.; Mallot, G.K.; Mann, A.; Marchand, C.; Martin, A.; Marzec, J.; Matsuda, T.; Meshcheryakov, G.; Meyer, W.; Michigami, T.; Mikhailov, Yu.V.; Moinester, M.A.; Morreale, A.; Mutter, A.; Nagaytsev, A.; Nagel, T.; Negrini, T.; Nerling, F.; Neubert, S.; Neyret, D.; Nikolaenko, V.I.; Nowak, W.D.; Nunes, A.S.; Olshevsky, A.G.; Ostrick, M.; Padee, A.; Panknin, R.; Panzieri, D.; Parsamyan, B.; Paul, S.; Perevalova, E.; Pesaro, G.; Peshekhonov, D.V.; Piragino, G.; Platchkov, S.; Pochodzalla, J.; Polak, J.; Polyakov, V.A.; Pretz, J.; Quaresma, M.; Quintans, C.; Rajotte, J.F.; Ramos, S.; Rapatsky, V.; Reicherz, G.; Richter, A.; Rocco, E.; Rondio, E.; Rossiyskaya, N.S.; Ryabchikov, D.I.; Samoylenko, V.D.; Sandacz, A.; Sapozhnikov, M.G.; Sarkar, S.; Savin, I.A.; Sbrizzai, G.; Schiavon, P.; Schill, C.; Schluter, T.; Schmidt, K.; Schmitt, L.; Schonning, K.; Schopferer, S.; Schott, M.; Schroder, W.; Shevchenko, O.Yu.; Silva, L.; Sinha, L.; Sissakian, A.N.; Slunecka, M.; Smirnov, G.I.; Sosio, S.; Sozzi, F.; Srnka, A.; Steiger, L.; Stolarski, M.; Sulc, M.; Sulej, R.; Suzuki, H.; Sznajder, P.; Takekawa, S.; Wolbeek, J.Ter; Tessaro, S.; Tessarotto, F.; Tkatchev, L.G.; Uhl, S.; Uman, I.; Vandenbroucke, M.; Virius, M.; Vlassov, N.V.; Wang, L.; Wilfert, M.; Windmolders, R.; Wislicki, W.; Wollny, H.; Zaremba, K.; Zavertyaev, M.; Zemlyanichkina, E.; Ziembicki, M.; Zhuravlev, N.; Zvyagin, A.

    2012-10-31

    The COMPASS Collaboration at CERN has measured the transverse spin azimuthal asymmetry of charged hadrons produced in semi-inclusive deep inelastic scattering using a 160 GeV positive muon beam and a transversely polarised NH_3 target. The Collins asymmetry of the proton was extracted in the Bjorken x range 0.003asymmetries for negative and positive hadrons are similar in magnitude and opposite in sign. They are compatible with model calculations in which the u-quark transversity is opposite in sign and somewhat larger than the d-quark transversity distribution function. The asymmetry is extracted as a function of Bjorken $x$, the relative hadron energy $z$ and the hadron transverse momentum p_T^h. The high statistics and quality of the data also allow for more detailed investigations of the dependence on the ki...

  10. Control of DNA strand displacement kinetics using toehold exchange.

    Science.gov (United States)

    Zhang, David Yu; Winfree, Erik

    2009-12-02

    DNA is increasingly being used as the engineering material of choice for the construction of nanoscale circuits, structures, and motors. Many of these enzyme-free constructions function by DNA strand displacement reactions. The kinetics of strand displacement can be modulated by toeholds, short single-stranded segments of DNA that colocalize reactant DNA molecules. Recently, the toehold exchange process was introduced as a method for designing fast and reversible strand displacement reactions. Here, we characterize the kinetics of DNA toehold exchange and model it as a three-step process. This model is simple and quantitatively predicts the kinetics of 85 different strand displacement reactions from the DNA sequences. Furthermore, we use toehold exchange to construct a simple catalytic reaction. This work improves the understanding of the kinetics of nucleic acid reactions and will be useful in the rational design of dynamic DNA and RNA circuits and nanodevices.

  11. Affect asymmetry and comfort food consumption.

    Science.gov (United States)

    Dubé, Laurette; LeBel, Jordan L; Lu, Ji

    2005-11-15

    It is proposed that the emotional triggers of comfort food consumption can reliably be predicted by factors tied to affect asymmetry whereby negative affects dominate one's experience, decision making and behaviors in some instances while positive emotions prevail in others. Specifically, we relate three of these factors (age, gender, and culture) to differences in the emotional triggers of comfort food consumption and we further explore the possibility that the type of food eaten during comfort-seeking episodes can also be tied to affect asymmetry. Two hundred and seventy-seven participants completed a web-based survey conducted to assess the emotional antecedents and consequences of comfort food consumption. Consistent with expectations, results indicate that men's comfort food consumption was motivated by positive emotions whereas women's consumption was triggered by negative affects. Consumption of comfort foods alleviated women's negative emotions but also produced guilt. Positive affect was a particularly powerful trigger of comfort food consumption for older participants and for participants with French cultural background. Younger participants and participants with English background reported more intense negative emotions prior to consuming comfort foods. Foods high in sugar and fat content were more efficient in alleviating negative affects whereas low-calorie foods were more efficient in increasing positive emotions.

  12. Does urban poverty increase body fluctuating asymmetry?

    Science.gov (United States)

    Ozener, Bariş

    2011-12-01

    Perturbations during development leave enduring signs on the adult body. Fluctuating asymmetry (FA) is a good bio-indicator of stress during ontogeny. The aim of this study is to determine the effect of urban poverty on the fluctuating asymmetry of young Turkish males. Young males from a lower socioeconomic group (N = 140, Mean age = 18.17 +/- 0.61) were selected from slum areas of Ankara, the capital of Turkey, where urban poverty is intense. An upper socioeconomic group, on the other hand, consisted of students from two private colleges and included children from some of the richest families in Turkey (N = 120, Mean age = 18.08 +/- 0.54). Eight anthropometric traits of all subjects were measured. Considering the seven measurements demonstrate ideal FA, the individuals living in poor areas of the city displayed higher FA. The discrepancy between the two groups was even greater for a measure of composite FA. In conclusion, poor living conditions in Ankara, where urban poverty is intense, adversely impact the developmental stability of young Turkish males.

  13. On Introducing Asymmetry into Circular Distributions

    Directory of Open Access Journals (Sweden)

    Dale Umbach

    2012-07-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} We give a brief history of the results which led to the introduction of asymmetry into symmetric circular distributions. This is followed by the presentation of another method of introducing asymmetry. Some properties of the induced distributions are studied. Finally, this new distribution is shown to be a reasonable fit to the Jander ant data as presented in Fisher (1993.

  14. Asymmetries in four powerful radio sources

    International Nuclear Information System (INIS)

    Lonsdale, C.J.; Morison, I.

    1983-01-01

    The extragalactic radio sources 3C 153, 196, 249.1 and 268.4 have been observed at frequencies of 408 and 1666 MHz with the new MERLIN array operated by Jodrell Bank, giving resolutions of approx. 0.9 and 0.25 arcsec respectively. The sources show marked asymmetries about the central object in spectral index, flux and morphology, which we believe are most naturally accounted for by the effects of a time-dependent asymmetry in the central powerhouse. In the case of 3C 249.1 the observations suggest that energy is being supplied alternately to the two sides of the source. The 1666-MHz observations also show that each of the other three sources contains one extremely compact hotspot. The minimum internal energy densities in these hotspots are such that confinement by ram pressure of motion through the intergalactic medium may not be possible, indicating that such features are transient phenomena in free expansion, or that some other confinement mechanism is operating. (author)

  15. Galactic cosmic rays and tropical ozone asymmetries

    International Nuclear Information System (INIS)

    Kilifarska, Natalya; Bakhmutov, Volodymyr; Melnyk, Galyna

    2017-01-01

    Lower stratospheric ozone O_3 is of special interest to climatic studies due to its direct influence on the tropopause temperature, and correspondingly on Earth’s radiation balance. By reason of the suppressed dissociation of molecular oxygen by solar UV radiation and the long life span of the lower stratospheric O_3 , its temporal variability is usually attributed to atmospheric circulation. Here we report about latitudinal-longitudinal differences in a centennial evolution of the tropical O_3 at 70 hPa. These asymmetries are hardly explicable within the concept of the ozone’s dynamical control alone. Analysis of ozone, energetic particles and the geomagnetic records from the last 111 years has revealed that they all evolve synchronously with time. This coherence motivates us to propose a mechanism explaining the geomagnetic and galactic cosmic ray influence on the near tropopause O_3 , allowing for an understanding of its spatial-temporal variability during the past century. Key words: galactic cosmic rays, asymmetries of tropical ozone distribution, geomagnetic filed

  16. Cholesterol asymmetry in synaptic plasma membranes.

    Science.gov (United States)

    Wood, W Gibson; Igbavboa, Urule; Müller, Walter E; Eckert, Gunter P

    2011-03-01

    Lipids are essential for the structural and functional integrity of membranes. Membrane lipids are not randomly distributed but are localized in different domains. A common characteristic of these membrane domains is their association with cholesterol. Lipid rafts and caveolae are examples of cholesterol enriched domains, which have attracted keen interest. However, two other important cholesterol domains are the exofacial and cytofacial leaflets of the plasma membrane. The two leaflets that make up the bilayer differ in their fluidity, electrical charge, lipid distribution, and active sites of certain proteins. The synaptic plasma membrane (SPM) cytofacial leaflet contains over 85% of the total SPM cholesterol as compared with the exofacial leaflet. This asymmetric distribution of cholesterol is not fixed or immobile but can be modified by different conditions in vivo: (i) chronic ethanol consumption; (ii) statins; (iii) aging; and (iv) apoE isoform. Several potential candidates have been proposed as mechanisms involved in regulation of SPM cholesterol asymmetry: apoE, low-density lipoprotein receptor, sterol carrier protein-2, fatty acid binding proteins, polyunsaturated fatty acids, P-glycoprotein and caveolin-1. This review examines cholesterol asymmetry in SPM, potential mechanisms of regulation and impact on membrane structure and function. © 2011 The Authors. Journal of Neurochemistry © 2011 International Society for Neurochemistry.

  17. Anterior EEG asymmetries and opponent process theory.

    Science.gov (United States)

    Kline, John P; Blackhart, Ginette C; Williams, William C

    2007-03-01

    The opponent process theory of emotion [Solomon, R.L., and Corbit, J.D. (1974). An opponent-process theory of motivation: I. Temporal dynamics of affect. Psychological Review, 81, 119-143.] predicts a temporary reversal of emotional valence during the recovery from emotional stimulation. We hypothesized that this affective contrast would be apparent in asymmetrical activity patterns in the frontal lobes, and would be more apparent for left frontally active individuals. The present study tested this prediction by examining EEG asymmetries during and after blocked presentations of aversive pictures selected from the International Affective Picture System (IAPS). 12 neutral images, 12 aversive images, and 24 neutral images were presented in blocks. Participants who were right frontally active at baseline did not show changes in EEG asymmetry while viewing aversive slides or after cessation. Participants left frontally active at baseline, however, exhibited greater relative left frontal activity after aversive stimulation than before stimulation. Asymmetrical activity patterns in the frontal lobes may relate to affect regulatory processes, including contrasting opponent after-reactions to aversive stimuli.

  18. Acute Pyelonephritis with Perinephric Stranding on CT

    Directory of Open Access Journals (Sweden)

    Ronald Goubert

    2018-01-01

    Full Text Available History of present illness: A 54-year old female presented to the emergency department with complaints of fevers, dysuria, urinary frequency, and diffuse abdominal pain. Her temperature was 103°F, but the remainder of her vital signs were normal. Upon physical examination, the patient had tenderness to palpation in the left upper and left lower abdomen and left costovertebral angle tenderness. Due to the location of pain (diverticulitis is in the differential for left-sided abdominal pain in this age group and patient’s reported history of nephrolithiasis, a computed tomography (CT scan of the abdomen and pelvis with intravenous (IV contrast was ordered because the physician felt this could best work up both of these possible conditions. Significant findings: A CT abdomen and pelvis with IV contrast showed neither nephrolithiasis nor diverticulitis, and instead showed heterogeneous enhancement of the left kidney with mild edematous enlargement and striated left nephrogram. Significant perinephric stranding (red arrows was also noted and was consistent with severe acute pyelonephritis. Discussion: Acute pyelonephritis (APN is a bacterial infection of the renal parenchyma which can present with a spectrum of symptoms including flank pain, high-grade fever, vomiting, and urinary tract symptoms.1,2 The diagnosis of APN can be made based on these clinical features with associated laboratory findings of bacteriuria, pyuria, positive urine cultures, and leukocytosis.1,2,7 Early diagnosis and treatment of APN is essential to prevent complications such as renal abscess or infarct, which could lead to renal failure, sepsis, and shock.3 CT has a sensitivity and specificity of 86.8% and 87.5%, respectively, for diagnosing APN. Common findings include striated nephrograms or perinephric fat stranding.2 However, imaging is not required for diagnosis and is typically reserved for patients who are immunocompromised, have severe symptoms, or show no clinical

  19. Double Stranded RNA in Human Seminal Plasma

    Directory of Open Access Journals (Sweden)

    Maxim V. Zagoskin

    2017-10-01

    Full Text Available Recently, human semen was shown to contain cell-free nucleic acids, such as DNA, long single stranded RNA, and small RNAs–miRNA and piRNA. The RNAs have been suggested to have potential biological roles as communication molecules between cells and in the temporal and spatial regulation of gene expression in the male reproductive system. Here we demonstrate that human seminal plasma contains a variety of cell-free dsRNAs, describe a robust method to isolate this type of nucleic acid in preparative amounts, and discuss the potential biological roles of these molecules in inheritance. dsRNA plays a role in a variety of biological processes, including gene regulation, is extremely stable and can gain access to cells from the extracellular medium. We suggest that one of the possible functions of dsRNA in human seminal plasma may be to influence human oocytes and therefore, influence the offspring. It also remains possible that these dsRNAs might have potential use as biomarkers for the study of human physiopathological conditions and genetic variation.

  20. Dynamics of Leading-strand Lesion Skipping by the Replisome

    Science.gov (United States)

    Yeeles, Joseph T.P.; Marians, Kenneth J.

    2013-01-01

    SUMMARY The E. coli replisome stalls transiently when it encounters a lesion in the leading-strand template, skipping over the damage by reinitiating replication at a new primer synthesized downstream by the primase. We report here that template unwinding and lagging-strand synthesis continue downstream of the lesion at a reduced rate after replisome stalling, that one replisome is capable of skipping multiple lesions, and that the rate limiting steps of replication restart involve the synthesis and activation of the new primer downstream. We also find little support for the concept that polymerase uncoupling, where extensive lagging-strand synthesis proceeds downstream in the absence of leading-strand synthesis, involves physical separation of the leading-strand polymerase from the replisome. Instead, our data indicate that extensive uncoupled replication likely results from a failure of the leading-strand polymerase still associated with the DNA helicase and the lagging-strand polymerase that are proceeding downstream to reinitiate synthesis. PMID:24268579

  1. Current redistribution in cables made of insulated, soldered, or oxidized strands

    International Nuclear Information System (INIS)

    Turck, B.

    1979-07-01

    Current redistributions are compared in cables made of insulated strands, soldered, or oxidized strands and insulated strands with periodic joints. After discussing the different current redistributions in the cases of a rapidly changing current and a dc current, several particular situations are investigated: what happens if a strand is broken, or if a local normal zone appears that does not affect all the strands equally, the detection of this normal zone, and the influence of short circuits between strands

  2. Disentangling the Relationship between Hemispheric Asymmetry and Cognitive Performance

    Science.gov (United States)

    Hirnstein, Marco; Leask, Stuart; Rose, Jonas; Hausmann, Markus

    2010-01-01

    It is widely believed that advantages of hemispheric asymmetries originated in better cognitive processing, hence it is often implied that the relationship between hemispheric asymmetry and cognitive performance is linearly positive: the higher the degree of lateralization in a specific cognitive domain, the better the performance in a…

  3. Asymmetries of Knowledge and Epistemic Change in Social Gaming Interaction

    Science.gov (United States)

    Piirainen-Marsh, Arja; Tainio, Liisa

    2014-01-01

    While a growing number of studies investigate the role of knowledge and interactional management of knowledge asymmetries in conversation analysis, the epistemic organization of multilingual and second language interactions is still largely unexplored. This article addresses this issue by investigating how knowledge asymmetries and changing…

  4. Information Asymmetries as Trade Barriers: ISO 9000 Increases International Commerce

    Science.gov (United States)

    Potoski, Matthew; Prakash, Aseem

    2009-01-01

    Spatial, cultural, and linguistic barriers create information asymmetries between buyers and sellers that impede international trade. The International Organization for Standardization's ISO 9000 program is designed to reduce these information asymmetries by providing assurance about the product quality of firms that receive its certification.…

  5. Identification of Foot Pathologies Based on Plantar Pressure Asymmetry

    Directory of Open Access Journals (Sweden)

    Linah Wafai

    2015-08-01

    Full Text Available Foot pathologies can negatively influence foot function, consequently impairing gait during daily activity, and severely impacting an individual’s quality of life. These pathologies are often painful and correspond with high or abnormal plantar pressure, which can result in asymmetry in the pressure distribution between the two feet. There is currently no general consensus on the presence of asymmetry in able-bodied gait, and plantar pressure analysis during gait is in dire need of a standardized method to quantify asymmetry. This paper investigates the use of plantar pressure asymmetry for pathological gait diagnosis. The results of this study involving plantar pressure analysis in fifty one participants (31 healthy and 20 with foot pathologies support the presence of plantar pressure asymmetry in normal gait. A higher level of asymmetry was detected at the majority of the regions in the feet of the pathological population, including statistically significant differences in the plantar pressure asymmetry in two regions of the foot, metatarsophalangeal joint 3 (MPJ3 and the lateral heel. Quantification of plantar pressure asymmetry may prove to be useful for the identification and diagnosis of various foot pathologies.

  6. Information Asymmetry and Financing Decisions: Evidence from Iran Stock Exchange

    OpenAIRE

    Mehdi Elhaei Sahar; Seyed Ali Vaez

    2013-01-01

    This study aims to investigate the relations of information asymmetry and financing decisions in Tehran Stock Exchange (TSE) during 2009 to 2011. Our statistical simple consist 170 firms and stepwise regression method has been used. We found that the relationship between information asymmetry and stock issuing is negative. Other results refer to positive relation between financing deficit and stock issuing.

  7. A Point-Wise Quantification of Asymmetry Using Deformation Fields

    DEFF Research Database (Denmark)

    Ólafsdóttir, Hildur; Lanche, Stephanie; Darvann, Tron Andre

    2007-01-01

    of the resulting displacement vectors on the left and right side of the symmetry plane, gives a point-wise measure of asymmetry. The asymmetry measure was applied to the study of Crouzon syndrome using Micro CT scans of genetically modified mice. Crouzon syndrome is characterised by the premature fusion of cranial...

  8. European economic integration and (A)symmetry of macroeconomic fluctuations

    NARCIS (Netherlands)

    Kool, C.J.M.; Economidou, C.

    2007-01-01

    This paper empirically investigates output and consumption asymmetries in the Eurozone and enlarged EU over the period 1992-2007, and their consequences for monetary policy. Our results reveal that the introduction of the euro has little impact on output asymmetry so far; however, it has led to

  9. CP violating rate asymmetries in B decays ∑

    Indian Academy of Sciences (India)

    CP violating rate asymmetries in B decays. N G DESHPANDE. Institute of Theoretical Science, University of Oregon, Eugene, Oregon 97403-5203, USA. Email: desh@oregon.uoregon.edu. Abstract. We briefly discuss measurements of angles β and α of the unitarity triangle. We then review rate asymmetries using SU´3µ ...

  10. Spatial asymmetry of post-stroke hemiparetic gait: assessment and ...

    African Journals Online (AJOL)

    Despite potential benefits, quantitative analysis of gait asymmetry is still not routinely used in many hospitals and rehabilitation institutions in developing countries due to ... Conclusion: Overall, the study demonstrated asymmetry of step length and foot rotation angle during walking of post-stroke hemiparetic individuals and ...

  11. Mapping hemispheric symmetries, relative asymmetries, and absolute asymmetries underlying the auditory laterality effect.

    Science.gov (United States)

    Westerhausen, René; Kompus, Kristiina; Hugdahl, Kenneth

    2014-01-01

    Functional hemispheric differences for speech and language processing have been traditionally studied by using verbal dichotic-listening paradigms. The commonly observed right-ear preference for the report of dichotically presented syllables is taken to reflect the left hemispheric dominance for speech processing. However, the results of recent functional imaging studies also show that both hemispheres - not only the left - are engaged by dichotic listening, suggesting a more complex relationship between behavioral laterality and functional hemispheric activation asymmetries. In order to more closely examine the hemispheric differences underlying dichotic-listening performance, we report an analysis of functional magnetic resonance imaging (fMRI) data of 104 right-handed subjects, for the first time combining an interhemispheric difference and conjunction analysis. This approach allowed for a distinction of homotopic brain regions which showed symmetrical (i.e., brain region significantly activated in both hemispheres and no activation difference between the hemispheres), relative asymmetrical (i.e., activated in both hemispheres but significantly stronger in one than the other hemisphere), and absolute asymmetrical activation patterns (i.e., activated only in one hemisphere and this activation is significantly stronger than in the other hemisphere). Symmetrical activation was found in large clusters encompassing temporal, parietal, inferior frontal, and medial superior frontal regions. Relative and absolute left-ward asymmetries were found in the posterior superior temporal gyrus, located adjacent to symmetrically activated areas, and creating a lateral-medial gradient from symmetrical towards absolute asymmetrical activation within the peri-Sylvian region. Absolute leftward asymmetry was also found in the post-central and medial superior frontal gyri, while rightward asymmetries were found in middle temporal and middle frontal gyri. We conclude that dichotic

  12. Towards quantitative viromics for both double-stranded and single-stranded DNA viruses

    Directory of Open Access Journals (Sweden)

    Simon Roux

    2016-12-01

    Full Text Available Background Viruses strongly influence microbial population dynamics and ecosystem functions. However, our ability to quantitatively evaluate those viral impacts is limited to the few cultivated viruses and double-stranded DNA (dsDNA viral genomes captured in quantitative viral metagenomes (viromes. This leaves the ecology of non-dsDNA viruses nearly unknown, including single-stranded DNA (ssDNA viruses that have been frequently observed in viromes, but not quantified due to amplification biases in sequencing library preparations (Multiple Displacement Amplification, Linker Amplification or Tagmentation. Methods Here we designed mock viral communities including both ssDNA and dsDNA viruses to evaluate the capability of a sequencing library preparation approach including an Adaptase step prior to Linker Amplification for quantitative amplification of both dsDNA and ssDNA templates. We then surveyed aquatic samples to provide first estimates of the abundance of ssDNA viruses. Results Mock community experiments confirmed the biased nature of existing library preparation methods for ssDNA templates (either largely enriched or selected against and showed that the protocol using Adaptase plus Linker Amplification yielded viromes that were ±1.8-fold quantitative for ssDNA and dsDNA viruses. Application of this protocol to community virus DNA from three freshwater and three marine samples revealed that ssDNA viruses as a whole represent only a minor fraction (<5% of DNA virus communities, though individual ssDNA genomes, both eukaryote-infecting Circular Rep-Encoding Single-Stranded DNA (CRESS-DNA viruses and bacteriophages from the Microviridae family, can be among the most abundant viral genomes in a sample. Discussion Together these findings provide empirical data for a new virome library preparation protocol, and a first estimate of ssDNA virus abundance in aquatic systems.

  13. Contract Design: The problem of information asymmetry

    Directory of Open Access Journals (Sweden)

    Axel C. Mühlbacher

    2018-01-01

    Full Text Available Introduction: Integrated care systems are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. Little is known about the contractual design and the main challenges of delegating “accountability” to these new kinds of organisations and/or contracts. The research question in this article focuses on how healthcare contracts can look like and which possible problems arise in designing such contracts. In this a special interest is placed on information asymmetries.  Methods: A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. This article is the first in a row of three that all contribute to a specific issue in designing healthcare contracts. Starting with the organisation of contracts and information asymmetries, part 2 focusses on financial options and risks and part 3 finally concludes with the question of risk management and evaluation.  Results: Healthcare contracting between providers and payers will have a major impact on the overall design of future healthcare systems. If Integrated care systems or any other similar concept of care delivery are to be contracted directly by payers to manage the continuum of care the costs of market utilisation play an essential role. Transaction costs also arise in the course of the negotiation and implementation of contracts. These costs are the reason why it is generally not possible to conclude perfect (complete contracts. Problems with asymmetric distribution of information can relate to the situation before a contract is concluded (adverse selection and after conclusion of a contract (moral hazard.  Discussion and Conclusions: Information asymmetries are seen as a major obstacle to the efficient operation of integrated care programmes. Coordination and motivation problems cannot be solved

  14. Strand critical current degradation in $Nb_{3}$ Sn Rutherford cables

    CERN Document Server

    Barzi, E; Higley, H C; Scanlan, R M; Yamada, R; Zlobin, A V

    2001-01-01

    Fermilab is developing 11 Tesla superconducting accelerator magnets based on Nb/sub 3/Sn superconductor. Multifilamentary Nb/sub 3/Sn strands produced using the modified jelly roll, internal tin, and powder-in-tube technologies were used for the development and test of the prototype cable. To optimize the cable geometry with respect to the critical current, short samples of Rutherford cable with packing factors in the 85 to 95% range were fabricated and studied. In this paper, the results of measurements of critical current, n-value and RRR made on the round virgin strands and on the strands extracted from the cable samples are presented. (5 refs).

  15. Frontal EEG asymmetry as a moderator and mediator of emotion.

    Science.gov (United States)

    Coan, James A; Allen, John J B

    2004-10-01

    Frontal EEG asymmetry appears to serve as (1) an individual difference variable related to emotional responding and emotional disorders, and (2) a state-dependent concomitant of emotional responding. Such findings, highlighted in this review, suggest that frontal EEG asymmetry may serve as both a moderator and a mediator of emotion- and motivation-related constructs. Unequivocal evidence supporting frontal EEG asymmetry as a moderator and/or mediator of emotion is lacking, as insufficient attention has been given to analyzing the frontal EEG asymmetries in terms of moderators and mediators. The present report reviews the frontal EEG asymmetry literature from the framework of moderators and mediators, and overviews data analytic strategies that would support claims of moderation and mediation.

  16. Fluctuating asymmetry, sociosexuality, and intrasexual competitive tactics.

    Science.gov (United States)

    Simpson, J A; Gangestad, S W; Christensen, P N; Leck, K

    1999-01-01

    Heterosexual men and women were told they were competing with another same-sex individual for a date with an attractive opposite-sex interviewer. After answering 6 questions, participants were asked to tell the competitor why the interviewer should choose them over the competitor. Participants' videotaped behavior was coded for different behavioral tactics. Men who were more symmetrical and who had a more unrestricted sociosexual orientation were more likely to use direct competition tactics than were less symmetrical and restricted men. Restricted men accentuated their positive personal qualities, presenting themselves as "nice guys." Structural equation modeling revealed that fluctuating asymmetry (FA) was directly associated with the use of direct competition tactics. However, the link between FA and presenting oneself as a nice guy was mediated through sociosexuality. No effects were found for women.

  17. The baryon asymmetry of the Universe

    International Nuclear Information System (INIS)

    Barrow, J.D.

    1980-01-01

    An interaction between cosmology and particle physics has been mediated by the development of a unified approach to the fundamental symmetries of nature. The development of a unified theory of the strong and electro-weak interactions has encountered a potential hurdle to its progress. The underlying symmetry between the strong and electro-weak interactions may only be restored at energies exceeding approximately 10 14 GeV and such conditions can only be probed by an indirect retrospection into the first instants of the hot big bang origin of the Universe. The author aims to describe some of the recent developments surrounding grand unified theories (GUT's) of the strong and electro-weak interactions together with their relation to the question of the matter-antimatter asymmetry of the Universe and the relative cosmic abundances of photons and nucleons. Further progress is hindered by the fact that super-unified theory must also encompass the gravitational interaction. (Auth.)

  18. The cosmological origin of time asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Castagnino, Mario [Instituto de Astronomia y Fisica del Espacio, Casilla de Correos 67, Sucursal 28, 1428 Buenos Aires (Argentina); Lara, Luis [Departamento de Fisica, Universidad Nacional de Rosario, Av. Pellegrini 250, 2000 Rosario (Argentina); Lombardi, Olimpia [CONICET - Universidad de Buenos Aires, Puan 470, 1406 Buenos Aires (Argentina)

    2003-01-21

    In this paper, we address the problem of the arrow of time from a cosmological point of view, rejecting the traditional entropic approach that defines the future direction of time as the direction of the entropy increase: from our perspective, the arrow of time has a global origin and it is an intrinsic, geometrical feature of spacetime. Time orientability and the existence of a cosmic time are necessary conditions for defining an arrow of time, which is manifested globally as the time asymmetry of the universe as a whole, and locally as a time-asymmetric energy flux. We also consider arrows of time of different origins (quantum, electromagnetic, thermodynamic, etc) showing that they can be non-conventionally defined only if the geometrical arrow is previously defined.

  19. A Combinatorial Approach to Time Asymmetry

    Directory of Open Access Journals (Sweden)

    Martin Tamm

    2016-03-01

    Full Text Available In this paper, simple models for the multiverse are analyzed. Each universe is viewed as a path in a graph, and by considering very general statistical assumptions, essentially originating from Boltzmann, we can make the set of all such paths into a finite probability space. We can then also attempt to compute the probabilities for different kinds of behavior and in particular under certain conditions argue that an asymmetric behavior of the entropy should be much more probable than a symmetric one. This offers an explanation for the asymmetry of time as a broken symmetry in the multiverse. The focus here is on simple models which can be analyzed using methods from combinatorics. Although the computational difficulties rapidly become enormous when the size of the model grows, this still gives hints about how a full-scale model should behave.

  20. Cultural Distance Asymmetry in Expatriate Adjustment

    DEFF Research Database (Denmark)

    Selmer, Jan; Chiu, Randy K.; Shenkar, Oded

    2007-01-01

    of the assignment. Design/methodology/approach - Using a two-flow sample of US expatriates in Germany and German expatriates in the USA, we examine and compare the psychological and socio-cultural adjustment of each group of executives. Findings - Controlling for the length of assignment, we find that German...... expatriates in the USA were better adjusted, both socio-culturally and psychologically, than American expatriates in Germany. These results support the asymmetry hypothesis and call into question previous findings attesting to the relationship between CD and expatriate adjustment. Originality......Purpose - The current literature implicitly assumes a symmetric impact of cultural distance (CD) on expatriate adjustment. By using distance as a predictor of adjustment, the literature has rendered the direction of the flow irrelevant: a US expatriate in Germany is presumed to face the same hurdle...

  1. Black hole thermodynamics and time asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Davies, P C.W. [King' s Coll., London (UK). Dept. of Mathematics

    1976-10-01

    The role of the gravitational field as a source of entropy is discussed, first in connection with cosmology, then for black holes. A review is given of the need for an assumption of 'molecular' chaos or randomness at the initial cosmological singularity, in order to achieve consistency of statistical mechanics with the observed time asymmetry in the universe. It is argued that a simple randomness assumption cannot always be made, because several singularities may be casually connected. The situation is compared with that of quantum black and white holes confined in a closed box. The possibility of black-hole fluctuations is discussed, together with Hawking's conjecture that black and white holes are indistinguishable.

  2. Symmetry and asymmetry in mandelate racemase catalysis

    International Nuclear Information System (INIS)

    Whitman, C.P.; Hegeman, G.D.; Cleland, W.W.; Kenyon, G.L.

    1985-01-01

    Kinetic properties of mandelate racemase catalysis (Vmax, Km, deuterium isotope effects, and pH profiles) were all measured in both directions by the circular dichroic assay of Sharp. These results, along with those of studying interactions of mandelate racemase with resolved, enantiomeric competitive inhibitors [(R)- and (S)-alpha-phenylglycerates], indicate a high degree of symmetry in both binding and catalysis. Racemization of either enantiomer of mandelate in D 2 O did not show an overshoot region of molecular ellipticity in circular dichroic measurements upon approach to equilibrium. Both the absence of such an overshoot region and the high degree of kinetic symmetry are consistent with a one-base acceptor mechanism for mandelate racemase. On the other hand, results of irreversible inhibition with partially resolved, enantiomeric affinity labels [(R)- and (S)-alpha-phenylglycidates] reveal a ''functional asymmetry'' at the active site. Mechanistic proposals, consistent with these results, are presented

  3. Lepton asymmetry and neutrino oscillations interplay

    Energy Technology Data Exchange (ETDEWEB)

    Kirilova, Daniela, E-mail: dani@astro.bas.bg [Bulgarian Academy of Sciences, Institute of Astronomy and NAO (Bulgaria)

    2013-03-15

    We discuss the interplay between lepton asymmetry L and {nu} oscillations in the early Universe. Neutrino oscillations may suppress or enhance previously existing L. On the other hand L is capable to suppress or enhance neutrino oscillations. The mechanism of L enhancement in MSW resonant {nu} oscillations in the early Universe is numerically analyzed. L cosmological effects through {nu} oscillations are discussed. We discuss how L may change the cosmological BBN constraints on neutrino and show that BBN model with {nu}{sub e}{r_reversible}{nu}{sub s} oscillations is extremely sensitive to L - it allows to obtain the most stringent constraints on L value. We discuss also the cosmological role of active-sterile {nu} mixing and L in connection with the indications about additional relativistic density in the early Universe, pointed out by BBN, CMB and LSS data and the analysis of global {nu} data.

  4. Assessing and conceptualizing frontal EEG asymmetry: An updated primer on recording, processing, analyzing, and interpreting frontal alpha asymmetry.

    Science.gov (United States)

    Smith, Ezra E; Reznik, Samantha J; Stewart, Jennifer L; Allen, John J B

    2017-01-01

    Frontal electroencephalographic (EEG) alpha asymmetry is widely researched in studies of emotion, motivation, and psychopathology, yet it is a metric that has been quantified and analyzed using diverse procedures, and diversity in procedures muddles cross-study interpretation. The aim of this article is to provide an updated tutorial for EEG alpha asymmetry recording, processing, analysis, and interpretation, with an eye towards improving consistency of results across studies. First, a brief background in alpha asymmetry findings is provided. Then, some guidelines for recording, processing, and analyzing alpha asymmetry are presented with an emphasis on the creation of asymmetry scores, referencing choices, and artifact removal. Processing steps are explained in detail, and references to MATLAB-based toolboxes that are helpful for creating and investigating alpha asymmetry are noted. Then, conceptual challenges and interpretative issues are reviewed, including a discussion of alpha asymmetry as a mediator/moderator of emotion and psychopathology. Finally, the effects of two automated component-based artifact correction algorithms-MARA and ADJUST-on frontal alpha asymmetry are evaluated. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Karyotype asymmetry in Cynodon Rich. (Poaceae) accessions.

    Science.gov (United States)

    Chiavegatto, R B; Paula, C M P; Souza Sobrinho, F; Benites, F R G; Techio, V H

    2016-12-02

    Cynodon is a genus of plants with forage potential that has attracted the interest of breeders. These species have high morphological variability in a large number of varieties and cytotypes, hampering identification. This study aimed to determine the karyotype asymmetry index among accessions of Cynodon to discriminate between them. Karyotype symmetry was based on three estimates, which were compared. The basic number for the genus is x = 9. The results of the chromosome count and DNA quantification, respectively, were as follows: two diploid accessions (2n = 2x = 18 and 1.08 ± 0.094 to 1.17 ± 0.036 pg DNA and ± standard deviation), one triploid accession (2n = 3x = 27 and 1.63 ± 0.017 pg DNA), four tetraploid accessions (2n = 4x = 36 and 1.88 ± 0.069 to 2.10 ± 0.07 pg DNA), and one pentaploid accession (2n = 5x = 45 and 2.55 ± 0.098 pg DNA). C. incompletus var. hirsutus had the longest total length of the haploid lot (29.05 µm), with chromosomes that ranged from 1.7 to 6.2 µm in length. On the basis of the karyotype asymmetry indices, the accessions were divided into two groups: 1) C. dactylon var. dactylon, C. transvaalensis, C. dactylon var. polevansii, three accessions of Cynodon sp, and C. nlemfuensis; and 2) C. incompletus var. hirsutus. This is the first description of tetraploidy in C. transvaalensis. The karyotypic data facilitated a determination of the degree of proximity between the accessions.

  6. Natural triple beta-stranded fibrous folds.

    Science.gov (United States)

    Mitraki, Anna; Papanikolopoulou, Katerina; Van Raaij, Mark J

    2006-01-01

    A distinctive family of beta-structured folds has recently been described for fibrous proteins from viruses. Virus fibers are usually involved in specific host-cell recognition. They are asymmetric homotrimeric proteins consisting of an N-terminal virus-binding tail, a central shaft or stalk domain, and a C-terminal globular receptor-binding domain. Often they are entirely or nearly entirely composed of beta-structure. Apart from their biological relevance and possible gene therapy applications, their shape, stability, and rigidity suggest they may be useful as blueprints for biomechanical design. Folding and unfolding studies suggest their globular C-terminal domain may fold first, followed by a "zipping-up" of the shaft domains. The C-terminal domains appear to be important for registration because peptides corresponding to shaft domains alone aggregate into nonnative fibers and/or amyloid structures. C-terminal domains can be exchanged between different fibers and the resulting chimeric proteins are useful as a way to solve structures of unknown parts of the shaft domains. The following natural triple beta-stranded fibrous folds have been discovered by X-ray crystallography: the triple beta-spiral, triple beta-helix, and T4 short tail fiber fold. All have a central longitudinal hydrophobic core and extensive intermonomer polar and nonpolar interactions. Now that a reasonable body of structural and folding knowledge has been assembled about these fibrous proteins, the next challenge and opportunity is to start using this information in medical and industrial applications such as gene therapy and nanotechnology.

  7. Equilibrious Strand Exchange Promoted by DNA Conformational Switching

    Science.gov (United States)

    Wu, Zhiguo; Xie, Xiao; Li, Puzhen; Zhao, Jiayi; Huang, Lili; Zhou, Xiang

    2013-01-01

    Most of DNA strand exchange reactions in vitro are based on toehold strategy which is generally nonequilibrium, and intracellular strand exchange mediated by proteins shows little sequence specificity. Herein, a new strand exchange promoted by equilibrious DNA conformational switching is verified. Duplexes containing c-myc sequence which is potentially converted into G-quadruplex are designed in this strategy. The dynamic equilibrium between duplex and G4-DNA is response to the specific exchange of homologous single-stranded DNA (ssDNA). The SER is enzyme free and sequence specific. No ATP is needed and the displaced ssDNAs are identical to the homologous ssDNAs. The SER products and exchange kenetics are analyzed by PAGE and the RecA mediated SER is performed as the contrast. This SER is a new feature of G4-DNAs and a novel strategy to utilize the dynamic equilibrium of DNA conformations.

  8. Mass strandings of various ommastrephid squid species have been ...

    African Journals Online (AJOL)

    spamer

    escape reaction, to jet backwards at speed, is commonly observed. Appearing to ... on the occasion of a single mass stranding (La Pylaie, as cited in Lane 1957). ..... have also been associated with the displacement of major water masses ...

  9. Corrosion performance of prestressing strands in contact with dissimilar grouts.

    Science.gov (United States)

    2013-01-01

    To improve the corrosion protection provided to prestressing strands, anti-bleed grouts are used to fill voids in post-tensioning : ducts that result from bleeding and shrinkage of older Portland Cement grouts. Environmental differences caused by exp...

  10. The risk of stranded assets for utilities in Canada

    International Nuclear Information System (INIS)

    Schroeder, W.

    1998-01-01

    The problems of dealing with stranded assets in Canada and the United States were discussed. Compared to the United States, the risk associated with stranded assets for utilities in Canada was considered to be relatively low because of the following factors: (1) low variable cost, (2) isolation, (3) lack of transmission interconnection capacity, (4) lack of tight synchronization in North America, (5) the likelihood of an increase in natural gas prices, (6) the absence of jurisdictional disputes such as FERC versus the states, (7) social considerations, (8) the learning curve, (9) politics, (10) weak balance sheets, (11) relatively low electricity prices, (12) the weak Canadian dollar, and (13) the possibility of refinancing at lower interest rates. Ontario Hydro, New Brunswick and Nova Scotia Power are the three Canadian utilities that may have stranded costs. For Ontario Hydro and New Brunswick Power the stranded costs would be related to nuclear generator problems, whereas for Nova Scotia Power, the stranded costs would be related to the thermal generating base, the threat from Sable Island Gas and the changing tax structure of the utility. Some other reasons why stranded assets could be created in Canada would include low variable costs and high fixed costs, over capacity of at least 30 per cent in generation, limited domestic energy growth, competitive threat from gas, reliability and safety of nuclear plants, and technology change. Five factors in terms of which stranded assets can be expressed are: (1) variable cost definition, (2) total cost definition, (3) operating profit definition, (4) wide geographic definition, and (5) free market definition. In calculating stranded assets, the number of years over which the assets are recovered and the discount rate are considered to be key factors. 26 tabs

  11. The Effect of Basepair Mismatch on DNA Strand Displacement

    OpenAIRE

    Broadwater, D.?W.?Bo; Kim, Harold?D.

    2016-01-01

    DNA strand displacement is a key reaction in DNA homologous recombination and DNA mismatch repair and is also heavily utilized in DNA-based computation and locomotion. Despite its ubiquity in science and engineering, sequence-dependent effects of displacement kinetics have not been extensively characterized. Here, we measured toehold-mediated strand displacement kinetics using single-molecule fluorescence in the presence of a single base pair mismatch. The apparent displacement rate varied si...

  12. Withdrawal Strength of Dowels in Plywood and Oriented Strand Board

    OpenAIRE

    ERDİL, Yusuf Z.; ECKELMAN, Carl A.

    2001-01-01

    Plywood and oriented strand board (OSB) are being used increasingly in the construction of upholstered furniture frames. Yet there is little information available concerning the holding strength of various fasteners, and, in particular, dowels in these materials. A study was conducted accordingly, to obtain basic information about the holding strength of dowels in both plywood and oriented strand board. Results of the tests were incorporated into predictive expressions that allow designers to...

  13. A model capturing novel strand symmetries in bacterial DNA

    International Nuclear Information System (INIS)

    Sobottka, Marcelo; Hart, Andrew G.

    2011-01-01

    Highlights: → We propose a simple stochastic model to construct primitive DNA sequences. → The model provide an explanation for Chargaff's second parity rule in primitive DNA sequences. → The model is also used to predict a novel type of strand symmetry in primitive DNA sequences. → We extend the results for bacterial DNA sequences and compare distributional properties intrinsic to the model to statistical estimates from 1049 bacterial genomes. → We find out statistical evidences that the novel type of strand symmetry holds for bacterial DNA sequences. -- Abstract: Chargaff's second parity rule for short oligonucleotides states that the frequency of any short nucleotide sequence on a strand is approximately equal to the frequency of its reverse complement on the same strand. Recent studies have shown that, with the exception of organellar DNA, this parity rule generally holds for double-stranded DNA genomes and fails to hold for single-stranded genomes. While Chargaff's first parity rule is fully explained by the Watson-Crick pairing in the DNA double helix, a definitive explanation for the second parity rule has not yet been determined. In this work, we propose a model based on a hidden Markov process for approximating the distributional structure of primitive DNA sequences. Then, we use the model to provide another possible theoretical explanation for Chargaff's second parity rule, and to predict novel distributional aspects of bacterial DNA sequences.

  14. Tissue strands as "bioink" for scale-up organ printing.

    Science.gov (United States)

    Yu, Yin; Ozbolat, Ibrahim T

    2014-01-01

    Organ printing, takes tissue spheroids as building blocks together with additive manufacturing technique to engineer tissue or organ replacement parts. Although a wide array of cell aggregation techniques has been investigated, and gained noticeable success, the application of tissue spheroids for scale-up tissue fabrication is still worth investigation. In this paper, we introduce a new micro-fabrication technique to create tissue strands at the scale of 500-700μm as a "bioink" for future robotic tissue printing. Printable alginate micro-conduits are used as semi-permeable capsules for tissue strand fabrication. Mouse insulinoma beta TC3 cell tissue strands were formed upon 4 days post fabrication with reasonable mechanical strength, high cell viability close to 90%, and tissue specific markers expression. Fusion was readily observed between strands when placing them together as early as 24h. Also, tissue strands were deposited with human umbilical vein smooth muscle cells (HUVSMCs) vascular conduits together to fabricated miniature pancreatic tissue analog. Our study provided a novel technique using tissue strands as "bioink" for scale-up bioprinting of tissues or organs.

  15. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand*

    Science.gov (United States)

    Teasley, Daniel C.; Parajuli, Shankar; Nguyen, Mai; Moore, Hayley R.; Alspach, Elise; Lock, Ying Jie; Honaker, Yuchi; Saharia, Abhishek; Piwnica-Worms, Helen; Stewart, Sheila A.

    2015-01-01

    The existence of redundant replication and repair systems that ensure genome stability underscores the importance of faithful DNA replication. Nowhere is this complexity more evident than in challenging DNA templates, including highly repetitive or transcribed sequences. Here, we demonstrate that flap endonuclease 1 (FEN1), a canonical lagging strand DNA replication protein, is required for normal, complete leading strand replication at telomeres. We find that the loss of FEN1 nuclease activity, but not DNA repair activities, results in leading strand-specific telomere fragility. Furthermore, we show that FEN1 depletion-induced telomere fragility is increased by RNA polymerase II inhibition and is rescued by ectopic RNase H1 expression. These data suggest that FEN1 limits leading strand-specific telomere fragility by processing RNA:DNA hybrid/flap intermediates that arise from co-directional collisions occurring between the replisome and RNA polymerase. Our data reveal the first molecular mechanism for leading strand-specific telomere fragility and the first known role for FEN1 in leading strand DNA replication. Because FEN1 mutations have been identified in human cancers, our findings raise the possibility that unresolved RNA:DNA hybrid structures contribute to the genomic instability associated with cancer. PMID:25922071

  16. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand.

    Science.gov (United States)

    Teasley, Daniel C; Parajuli, Shankar; Nguyen, Mai; Moore, Hayley R; Alspach, Elise; Lock, Ying Jie; Honaker, Yuchi; Saharia, Abhishek; Piwnica-Worms, Helen; Stewart, Sheila A

    2015-06-12

    The existence of redundant replication and repair systems that ensure genome stability underscores the importance of faithful DNA replication. Nowhere is this complexity more evident than in challenging DNA templates, including highly repetitive or transcribed sequences. Here, we demonstrate that flap endonuclease 1 (FEN1), a canonical lagging strand DNA replication protein, is required for normal, complete leading strand replication at telomeres. We find that the loss of FEN1 nuclease activity, but not DNA repair activities, results in leading strand-specific telomere fragility. Furthermore, we show that FEN1 depletion-induced telomere fragility is increased by RNA polymerase II inhibition and is rescued by ectopic RNase H1 expression. These data suggest that FEN1 limits leading strand-specific telomere fragility by processing RNA:DNA hybrid/flap intermediates that arise from co-directional collisions occurring between the replisome and RNA polymerase. Our data reveal the first molecular mechanism for leading strand-specific telomere fragility and the first known role for FEN1 in leading strand DNA replication. Because FEN1 mutations have been identified in human cancers, our findings raise the possibility that unresolved RNA:DNA hybrid structures contribute to the genomic instability associated with cancer. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  17. Kinetic asymmetries between forward and drop jump landing tasks

    Directory of Open Access Journals (Sweden)

    Morgana Alves de Britto

    2015-12-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2015v17n6p661   Landing asymmetry is a risk factor for knee anterior cruciate ligament injury. The aim of this study was to identify kinetic asymmetries in healthy recreational athletes performing different jump-landing techniques. Twelve recreational athletes engaged in regular training underwent kinetic evaluation using two 3D force plates and were analyzed for: (a three-dimensional peak forces, (b time to peak vertical force, and (c initial phase asymmetries. All data were collected during performance of unilateral and bilateral trials of forward and drop jump tasks. Forward jump-landing tasks elicited greater kinetic asymmetry than drop-landing tasks. Regardless of jump-landing technique, the preferred leg experienced higher forces than the non-preferred leg. The initial landing phase showed more kinetic asymmetries than the later phase when peak vertical forces occur. It was concluded that when screening athletes for kinetic asymmetries that may predispose them to injury, forward jump-landing tasks and the early landing phase might show more kinetic asymmetries than drop jump-landing tasks and the late landing phase, respectively.

  18. Magnetic fields and chiral asymmetry in the early hot universe

    International Nuclear Information System (INIS)

    Sydorenko, Maksym; Shtanov, Yuri; Tomalak, Oleksandr

    2016-01-01

    In this paper, we study analytically the process of external generation and subsequent free evolution of the lepton chiral asymmetry and helical magnetic fields in the early hot universe. This process is known to be affected by the Abelian anomaly of the electroweak gauge interactions. As a consequence, chiral asymmetry in the fermion distribution generates magnetic fields of non-zero helicity, and vice versa. We take into account the presence of thermal bath, which serves as a seed for the development of instability in magnetic field in the presence of externally generated lepton chiral asymmetry. The developed helical magnetic field and lepton chiral asymmetry support each other, considerably prolonging their mutual existence, in the process of 'inverse cascade' transferring magnetic-field power from small to large spatial scales. For cosmologically interesting initial conditions, the chiral asymmetry and the energy density of helical magnetic field are shown to evolve by scaling laws, effectively depending on a single combined variable. In this case, the late-time asymptotics of the conformal chiral chemical potential reproduces the universal scaling law previously found in the literature for the system under consideration. This regime is terminated at lower temperatures because of scattering of electrons with chirality change, which exponentially washes out chiral asymmetry. We derive an expression for the termination temperature as a function of the chiral asymmetry and energy density of helical magnetic field.

  19. Shifting brain asymmetry: the link between meditation and structural lateralization.

    Science.gov (United States)

    Kurth, Florian; MacKenzie-Graham, Allan; Toga, Arthur W; Luders, Eileen

    2015-01-01

    Previous studies have revealed an increased fractional anisotropy and greater thickness in the anterior parts of the corpus callosum in meditation practitioners compared with control subjects. Altered callosal features may be associated with an altered inter-hemispheric integration and the degree of brain asymmetry may also be shifted in meditation practitioners. Therefore, we investigated differences in gray matter asymmetry as well as correlations between gray matter asymmetry and years of meditation practice in 50 long-term meditators and 50 controls. We detected a decreased rightward asymmetry in the precuneus in meditators compared with controls. In addition, we observed that a stronger leftward asymmetry near the posterior intraparietal sulcus was positively associated with the number of meditation practice years. In a further exploratory analysis, we observed that a stronger rightward asymmetry in the pregenual cingulate cortex was negatively associated with the number of practice years. The group difference within the precuneus, as well as the positive correlations with meditation years in the pregenual cingulate cortex, suggests an adaptation of the default mode network in meditators. The positive correlation between meditation practice years and asymmetry near the posterior intraparietal sulcus may suggest that meditation is accompanied by changes in attention processing. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  20. PirB regulates asymmetries in hippocampal circuitry.

    Directory of Open Access Journals (Sweden)

    Hikari Ukai

    Full Text Available Left-right asymmetry is a fundamental feature of higher-order brain structure; however, the molecular basis of brain asymmetry remains unclear. We recently identified structural and functional asymmetries in mouse hippocampal circuitry that result from the asymmetrical distribution of two distinct populations of pyramidal cell synapses that differ in the density of the NMDA receptor subunit GluRε2 (also known as NR2B, GRIN2B or GluN2B. By examining the synaptic distribution of ε2 subunits, we previously found that β2-microglobulin-deficient mice, which lack cell surface expression of the vast majority of major histocompatibility complex class I (MHCI proteins, do not exhibit circuit asymmetry. In the present study, we conducted electrophysiological and anatomical analyses on the hippocampal circuitry of mice with a knockout of the paired immunoglobulin-like receptor B (PirB, an MHCI receptor. As in β2-microglobulin-deficient mice, the PirB-deficient hippocampus lacked circuit asymmetries. This finding that MHCI loss-of-function mice and PirB knockout mice have identical phenotypes suggests that MHCI signals that produce hippocampal asymmetries are transduced through PirB. Our results provide evidence for a critical role of the MHCI/PirB signaling system in the generation of asymmetries in hippocampal circuitry.

  1. Bilateral asymmetry of the humerus during growth and development.

    Science.gov (United States)

    Blackburn, Amanda

    2011-08-01

    The development of handedness throughout growth can be investigated by using bilateral asymmetry of the humerus as a proxy for this trait. A large skeletal sample of nonadults from English archaeological sites was examined using standard metric techniques to assess when right-sided asymmetry first appears in the human skeleton. Results of this work indicate a change in directional asymmetry during growth and development, with infants and young children exhibiting no significant asymmetry and older children and adolescents demonstrating right-sidedness. This trend is consistent with what has been observed in previous studies of upper limb asymmetry in skeletal material and behaviorally in living children, adding further strength to the premise that biomechanical forces strongly influence bilateral asymmetry in the upper limb bones. Variability in the magnitude of asymmetry between different features of the humerus was also noted. This characteristic can be explained by differing degrees of genetic canalization, with length and articular dimensions being more strongly canalized than diaphyseal properties. Copyright © 2011 Wiley-Liss, Inc.

  2. Magnetic fields and chiral asymmetry in the early hot universe

    Energy Technology Data Exchange (ETDEWEB)

    Sydorenko, Maksym; Shtanov, Yuri [Bogolyubov Institute for Theoretical Physics, 03680 Kiev (Ukraine); Tomalak, Oleksandr, E-mail: maxsydorenko@gmail.com, E-mail: tomalak@uni-mainz.de, E-mail: shtanov@bitp.kiev.ua [Institut für Kernphysik, Johannes Gutenberg Universität, 55128 Mainz (Germany)

    2016-10-01

    In this paper, we study analytically the process of external generation and subsequent free evolution of the lepton chiral asymmetry and helical magnetic fields in the early hot universe. This process is known to be affected by the Abelian anomaly of the electroweak gauge interactions. As a consequence, chiral asymmetry in the fermion distribution generates magnetic fields of non-zero helicity, and vice versa. We take into account the presence of thermal bath, which serves as a seed for the development of instability in magnetic field in the presence of externally generated lepton chiral asymmetry. The developed helical magnetic field and lepton chiral asymmetry support each other, considerably prolonging their mutual existence, in the process of 'inverse cascade' transferring magnetic-field power from small to large spatial scales. For cosmologically interesting initial conditions, the chiral asymmetry and the energy density of helical magnetic field are shown to evolve by scaling laws, effectively depending on a single combined variable. In this case, the late-time asymptotics of the conformal chiral chemical potential reproduces the universal scaling law previously found in the literature for the system under consideration. This regime is terminated at lower temperatures because of scattering of electrons with chirality change, which exponentially washes out chiral asymmetry. We derive an expression for the termination temperature as a function of the chiral asymmetry and energy density of helical magnetic field.

  3. Interplay among transversity induced asymmetries in hadron leptoproduction

    Directory of Open Access Journals (Sweden)

    C. Adolph

    2016-02-01

    Full Text Available In the fragmentation of a transversely polarized quark several left–right asymmetries are possible for the hadrons in the jet. When only one unpolarized hadron is selected, it exhibits an azimuthal modulation known as the Collins effect. When a pair of oppositely charged hadrons is observed, three asymmetries can be considered, a di-hadron asymmetry and two single hadron asymmetries. In lepton deep inelastic scattering on transversely polarized nucleons all these asymmetries are coupled with the transversity distribution. From the high statistics COMPASS data on oppositely charged hadron-pair production we have investigated for the first time the dependence of these three asymmetries on the difference of the azimuthal angles of the two hadrons. The similarity of transversity induced single and di-hadron asymmetries is discussed. A new analysis of the data allows quantitative relationships to be established among them, providing for the first time strong experimental indication that the underlying fragmentation mechanisms are all driven by a common physical process.

  4. Unilateral condylar hyperplasia: a 3-dimensional quantification of asymmetry.

    Directory of Open Access Journals (Sweden)

    Tim J Verhoeven

    Full Text Available PURPOSE: Objective quantifications of facial asymmetry in patients with Unilateral Condylar Hyperplasia (UCH have not yet been described in literature. The aim of this study was to objectively quantify soft-tissue asymmetry in patients with UCH and to compare the findings with a control group using a new method. MATERIAL AND METHODS: Thirty 3D photographs of patients diagnosed with UCH were compared with 30 3D photographs of healthy controls. As UCH presents particularly in the mandible, a new method was used to isolate the lower part of the face to evaluate asymmetry of this part separately. The new method was validated by two observers using 3D photographs of five patients and five controls. RESULTS: A significant difference (0.79 mm between patients and controls whole face asymmetry was found. Intra- and inter-observer differences of 0.011 mm (-0.034-0.011 and 0.017 mm (-0.007-0.042 respectively were found. These differences are irrelevant in clinical practice. CONCLUSION: After objective quantification, a significant difference was identified in soft-tissue asymmetry between patients with UCH and controls. The method used to isolate mandibular asymmetry was found to be valid and a suitable tool to evaluate facial asymmetry.

  5. Measurement of ttbar forward-backward asymmetry at CDF

    CERN Multimedia

    CERN. Geneva

    2011-01-01

    Early measurements of the forward-backward ttbar production asymmetry at CDF and D0 suggested significant asymmetries that have been interpreted as evidence for exotic gluon partners or new t-channel interactions. We present new measurements performed with 5 fb-1 of Tevatron ppbar collisions at Ecm = 1.96 TeV, recorded and analyzed at CDF. Significant inclusive asymmetries are observed in both the lepton+jets and the dilepton decay modes of the ttbar pair. In the dilepton mode, the asymmetry is observed in the reconstructed top rapidity, and in the lepton rapidity difference, which is independent of any top reconstruction. In the lepton plus jets sample, the full reconstruction of the top kinematics is used to measure the dependence of the asymmetry on the tt bar rapidity difference Delta(y) and the invariant mass M_(ttbar ) of the ttbar system. The asymmetry is found to be most significant at large Delta(y) and M_(ttbar) . For M_(ttbar) > 450 GeV/c2, the parton-level asymmetry in the t-tbar rest frame is...

  6. North-South asymmetry of interplanetary plasma and solar parameters

    International Nuclear Information System (INIS)

    El-Borie, M. A.

    2001-01-01

    Data of interplanetary plasma (field magnitude, solar wind speed, ion plasma density and temperature) and solar parameters (sunspot number, solar radio flux, and geomagnetic index) over the period 1965-1991, have been used to examine the asymmetry between the solar field north and south of the heliospheric current sheet (HCS). The dependence of N-S asymmetry of field magnitude (B) upon the interplanetary solar polarities is statistically insignificant. There is no clear indication for the presence of N-S asymmetry in the grand-average field magnitude over the solar cycles. During the period 1981-89 (qA<0; negative solar polarity state), the solar plasma was more dense and cooler south of the HCS than north of it. The solar flux component of toward field vector is larger in magnitude than those of away field vector during the qA<0 epoch, and no asymmetry observed in the qA<0 epoch. Furthermore, the sign of the N-S asymmetry in the solar activity depends positively upon the solar polarity state. In addition, it was studied the N-S asymmetry of solar parameters near the HCS, throughout the periods of northern and southern hemispheres were more active than the other. Some asymmetries (with respect to the HCS) in plasma parameters existed during the periods of southern hemisphere predominance

  7. Age and Practice Effects on Inter-manual Performance Asymmetry

    Directory of Open Access Journals (Sweden)

    Karen L Francis

    2015-01-01

    Full Text Available Manual dexterity declines with increasing age however, the way in which inter-manual asymmetry responds to aging is unclear. Our purpose was to determine the effect of age and practice on inter-manual performance asymmetry in an isometric force pinch line tracing task that varied in difficulty within segments. Thirty right handed participants, 5 males and 5 females in each of three age groups, young (Y20, young-old (O70, and old-old (O80, practiced an isometric force pinch task for 10 trials with each hand on each of five consecutive days. Inter-manual performance asymmetry of the right and left hands was analyzed with a repeated measures ANOVA of asymmetry with age groups, practice, task difficulty, and hand as factors. The within-individual magnitude of asymmetry was also analyzed with a repeated measures ANOVA of manual asymmetry calculated as an asymmetry index (AI. Post hoc pair-wise comparisons were performed when significance was found. We observed no inter-manual performance asymmetry on this isometric tracing task among any of the age groups, either in the hand performance differences or in the magnitude of the asymmetry index (AI. Age and practice interacted in terms of manual performance: the Y20 and O70 group improved accuracy and task time across the five days of practice but the O80 group did not. However, practice did not differentially affect the AI for accuracy or task time for any group. Accuracy of performance of the two hands was differentially affected by practice. All age groups exhibited poorer performance and larger AIs on the most difficult segments of the task (3 and 6 and this did not change with practice.

  8. Red Tide Strands South African Rock Lobsters

    Science.gov (United States)

    2002-01-01

    Although some red tides form a healthy part of phytoplankton production, recurrent harmful or toxic blooms also occur, with results depending upon the type of plankton and on atmospheric and oceanic conditions. At Elands Bay in South Africa's Western Cape province, about 1000 tons of rock lobsters beached themselves during February 2002, when the decay of dense blooms of phytoplankton caused a rapid reduction in the oxygen concentration of nearshore waters. The lobsters (or crayfish, as they are known locally) moved toward the breaking surf in search of oxygen, but were stranded by the retreating tide. The Multi-angle Imaging SpectroRadiometer's nadir camera acquired these red, green, blue composites on February 2 and 18, 2002, during Terra orbits 11315 and 11548. The colors have been accentuated to highlight the bloom, and land and water have been enhanced separately. The two views show the shoreward migration of the algal bloom. Each image represents an area of about 205 kilometers x 330 kilometers. Elands Bay is situated near the mouth of the Doring River, about 75 kilometers northeast of the jutting Cape Columbine. The term 'red tide' is used to refer to a number of different types of phytoplankton blooms of various hues. The wine color of certain parts of this bloom are consistent with the ciliate species Mesodinium rubrum, which has been associated with recurring harmful algal blooms along the Western Cape coast. Under these conditions, the lobsters are not poisoned. During the recent event, government and military staff transported as many of the living lobsters as possible to areas that were less affected by the red tide. At the same time, people came from across South Africa to gather the undersized creatures for food. The effects of the losses on the maritime economy are expected to be felt over the next few years. MISR was built and is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Office of Earth Science, Washington, DC. The Terra

  9. Next to leading order semi-inclusive spin asymmetries

    International Nuclear Information System (INIS)

    Florian, D. de; Epele, L.N.; Fanchiotti, H.; Garcia C, C.A.; Sassot, R.

    1996-04-01

    We have computed semi-inclusive spin asymmetries for proton and deuteron targets including next to leading order (NLO) QCD corrections and contributions coming from the target fragmentation region. These corrections have been estimated using NLO fragmentation functions, parton distributions and also a model for spin dependent fracture functions which is proposed here. We have found that NLO corrections are small but non-negligible in a scheme where gluons are polarised and that our estimate for target fragmentation effects, which is in agreement with the available semi-inclusive data, does not modify significantly charged asymmetries but is non-negligible for the so called difference asymmetries. (author). 18 refs., 7 figs

  10. Forward-backward asymmetries in W and Z decays

    International Nuclear Information System (INIS)

    Rosner, J.L.; Langacker, P.; Robinett, R.W.

    1984-01-01

    The leptons emitted in decays of W and Z bosons produced in pp or anti pp collisions exhibit characteristic asymmetries with respect to the beam direction, as measured in the W or Z center-of-mass. The asymmetries appear in both pp and anti pp collisions. For anti pp collisions they appear to be approximately constant over the whole y range for values of M/√s greater than or equal to 0.1. For smaller values of M/√s, the asymmetries become more and more washed out in the central region as sea-sea collisions begin to play a larger role in gauge boson formation

  11. The small mixing angle $\\theta_{13}$ and the lepton asymmetry

    CERN Document Server

    Lee, S H; Lee, Song-Haeng; Siyeon, Kim

    2005-01-01

    We present the correlation of low energy CP phases, both Dirac and Majorana, and the lepton asymmetry for the baryon asymmetry in the universe, with a certain class of Yukawa matrices that consist of two right-handed neutrinos and include one texture zero in themselves. For cases in which the amount of the lepton asymmetry $Y_L$ turns out to be proportional to $\\theta_{13}^2$, we consider the relation between two types of CP phases and the relation of $Y_L$ versus the Jarlskog invariant or the amplitude of neutrinoless double beta decay as $\\theta_{13}$ varies.

  12. Measuring the cosmological lepton asymmetry through the CMB anisotropy

    CERN Document Server

    Kinney, W H; Kinney, William H.; Riotto, Antonio

    1999-01-01

    A large lepton asymmetry in the Universe is still a viable possibility and leads to many interesting phenomena such as gauge symmetry nonrestoration at high temperature. We show that a large lepton asymmetry changes the predicted cosmic microwave background (CMB) anisotropy and that any degeneracy in the relic neutrino sea will be measured to a precision of 1% or better when the CMB anisotropy is measured at the accuracy expected to result from the planned satellite missions MAP and Planck. In fact, the current measurements already put an upper limit on the lepton asymmetry of the Universe which is stronger than the one coming from considerations of primordial nucleosynthesis and structure formation.

  13. Baryogenesis and Dark Matter through a Higgs Asymmetry

    CERN Document Server

    Servant, Geraldine

    2013-01-01

    In addition to explaining the masses of elementary particles, the Higgs boson may have far-reaching implications for the generation of the matter content in the Universe. For instance, the Higgs plays a key role in two main theories of baryogenesis, namely electroweak baryogenesis and leptogenesis. In this letter, we propose a new cosmological scenario where the Higgs chemical potential mediates asymmetries between visible and dark matter sectors, either generating a baryon asymmetry from a dark matter asymmetry or vice-versa. We illustrate this mechanism with a simple model with two new fermions coupled to the Higgs and discuss associated signatures.

  14. Baryogenesis and dark matter through a Higgs asymmetry.

    Science.gov (United States)

    Servant, Géraldine; Tulin, Sean

    2013-10-11

    In addition to explaining the masses of elementary particles, the Higgs boson may have far-reaching implications for the generation of the matter content in the Universe. For instance, the Higgs boson plays a key role in two main theories of baryogenesis, namely, electroweak baryogenesis and leptogenesis. In this Letter, we propose a new cosmological scenario where the Higgs chemical potential mediates asymmetries between visible and dark matter sectors, either generating a baryon asymmetry from a dark matter asymmetry or vice versa. We illustrate this mechanism with a simple model with two new fermions coupled to the Higgs boson and discuss the associated signatures.

  15. Role of allosteric switch residue histidine 195 in maintaining active-site asymmetry in presynaptic filaments of bacteriophage T4 UvsX recombinase.

    Science.gov (United States)

    Farb, Joshua N; Morrical, Scott W

    2009-01-16

    Recombinases of the highly conserved RecA/Rad51 family play central roles in homologous recombination and DNA double-stranded break repair. RecA/Rad51 enzymes form presynaptic filaments on single-stranded DNA (ssDNA) that are allosterically activated to catalyze ATPase and DNA strand-exchange reactions. Information is conveyed between DNA- and ATP-binding sites, in part, by a highly conserved glutamine residue (Gln194 in Escherichia coli RecA) that acts as an allosteric switch. The T4 UvsX protein is a divergent RecA ortholog and contains histidine (His195) in place of glutamine at the allosteric switch position. UvsX and RecA catalyze similar strand-exchange reactions, but differ in other properties. UvsX produces both ADP and AMP as products of its ssDNA-dependent ATPase activity--a property that is unique among characterized recombinases. Details of the kinetics of ssDNA-dependent ATP hydrolysis reactions indicate that UvsX-ssDNA presynaptic filaments are asymmetric and contain two classes of ATPase active sites: one that generates ADP, and another that generates AMP. Active-site asymmetry is reduced by mutations at the His195 position, since UvsX-H195Q and UvsX-H195A mutants both exhibit stronger ssDNA-dependent ATPase activity, with lower cooperativity and markedly higher ADP/AMP product ratios, than wild-type UvsX. Reduced active-site asymmetry correlates strongly with reduced ssDNA-binding affinity and DNA strand-exchange activity in both H195Q and H195A mutants. These and other results support a model in which allosteric switch residue His195 controls the formation of an asymmetric conformation of UvsX-ssDNA filaments that is active in DNA strand exchange. The implications of our findings for UvsX recombination functions, and for RecA functions in general, are discussed.

  16. The importance of becoming double-stranded: Innate immunity and the kinetic model of HIV-1 central plus strand synthesis

    International Nuclear Information System (INIS)

    Poeschla, Eric

    2013-01-01

    Central initiation of plus strand synthesis is a conserved feature of lentiviruses and certain other retroelements. This complication of the standard reverse transcription mechanism produces a transient “central DNA flap” in the viral cDNA, which has been proposed to mediate its subsequent nuclear import. This model has assumed that the important feature is the flapped DNA structure itself rather than the process that produces it. Recently, an alternative kinetic model was proposed. It posits that central plus strand synthesis functions to accelerate conversion to the double-stranded state, thereby helping HIV-1 to evade single-strand DNA-targeting antiviral restrictions such as APOBEC3 proteins, and perhaps to avoid innate immune sensor mechanisms. The model is consistent with evidence that lentiviruses must often synthesize their cDNAs when dNTP concentrations are limiting and with data linking reverse transcription and uncoating. There may be additional kinetic advantages for the artificial genomes of lentiviral gene therapy vectors. - Highlights: • Two main functional models for HIV central plus strand synthesis have been proposed. • In one, a transient central DNA flap in the viral cDNA mediates HIV-1 nuclear import. • In the other, multiple kinetic consequences are emphasized. • One is defense against APOBEC3G, which deaminates single-stranded DNA. • Future questions pertain to antiviral restriction, uncoating and nuclear import

  17. Tensile and dimensional properties of wood strands made from plantation southern pine lumber

    Science.gov (United States)

    Qinglin Wu; Zhiyong Cai; Jong N. Lee

    2005-01-01

    Working stresses and performance of strand composite lumber largely depend upon the properties of each individual strand. Southern pine strands from plantation lumber grown in southern Louisiana were investigated in this study in order to understand strand behaviors. The effects of hot-pressing and resin application on tensile modulus, strength, and dimensional...

  18. Role of stranded gas in increasing global gas supplies

    Science.gov (United States)

    Attanasi, E.D.; Freeman, P.A.

    2013-01-01

    This report synthesizes the findings of three regional studies in order to evaluate, at the global scale, the contribution that stranded gas resources can make to global natural gas supplies. Stranded gas, as defined for this study, is natural gas in discovered conventional gas and oil fields that is currently not commercially producible for either physical or economic reasons. The regional studies evaluated the cost of bringing the large volumes of undeveloped gas in stranded gas fields to selected markets. In particular, stranded gas fields of selected Atlantic Basin countries, north Africa, Russia, and central Asia are screened to determine whether the volumes are sufficient to meet Europe’s increasing demand for gas imports. Stranded gas fields in Russia, central Asia, Southeast Asia, and Australia are also screened to estimate development, production, and transport costs and corresponding gas volumes that could be supplied to Asian markets in China, India, Japan, and South Korea. The data and cost analysis presented here suggest that for the European market and the markets examined in Asia, the development of stranded gas provides a way to meet projected gas import demands for the 2020-to-2040 period. Although this is a reconnaissance-type appraisal, it is based on volumes of gas that are associated with individual identified fields. Individual field data were carefully examined. Some fields were not evaluated because current technology was insufficient or it appeared the gas was likely to be held off the export market. Most of the evaluated stranded gas can be produced and delivered to markets at costs comparable to historical prices. Moreover, the associated volumes of gas are sufficient to provide an interim supply while additional technologies are developed to unlock gas diffused in shale and hydrates or while countries transition to making a greater use of renewable energy sources.

  19. Stranding Events of Kogia Whales along the Brazilian Coast.

    Directory of Open Access Journals (Sweden)

    Jailson F Moura

    Full Text Available The genus Kogia, which comprises only two extant species, Kogia sima and Kogia breviceps, represents one of the least known groups of cetaceans in the global ocean. In some coastal regions, however, stranding events of these species have been relatively common over the last decades. Stranding provides the opportunity to investigate the biology of these cetaceans and to explore the epidemiological aspects associated with the mortality of the organisms found on the beach. A number of disturbances (including pelagic fisheries, chemical pollution, boat strikes, and noise pollution have been confirmed to pose a particular threat to the Kogia species. However, no study has yet investigated potential relationships between environmental conditions and stranding events. Here we analyse how a collection of environmental, physical, and biological variables, such as wind, sea surface temperature (SST, water depth, and chlorophyll-a, correlate to Kogia stranding events along the Brazilian coast. The results of our statistical analyses suggest that K. sima is more likely found in warm tropical waters, which provide an explanation for the high frequency of stranding in northeastern Brazilian coast. In contrast, K. breviceps appears to have a preference for temperate and productive waters. Wind speed results to be also an important factor for predicting Kogia strandings in Brazilian coast. Additionally, literature information in combination with our own data and analyses of stomach contents confirms that oceanic cephalopods constitute the primary nutritional source of both Kogia species. By using the available information as a qualitative proxy for habitat preference and feeding ecology, our study provides a novel and comprehensive assessment of Kogia stranding data in relation to environmental conditions along the Brazilian coast.

  20. Value, obligation and the asymmetry question.

    Science.gov (United States)

    Tooley, Michael

    1998-04-01

    Is there a prima facie obligation to produce additional individuals whose lives would be worth living? In his paper 'Is it good to make happy people?', Stuart Rachels argues not only that there is, but, also, that precisely as much weight should be assigned to the quality of life that would be enjoyed by such potential persons, if they were to be actualized, as to the quality of life enjoyed by actually existing persons. In response, I shall argue, first, that Rachels' view is exposed to very serious objections, and secondly, that his arguments in support of his position involve a crucial assumption, which cannot be sustained, concerning the relation between, on the one hand, propositions about good-making and bad-making properties, and, on the other, propositions about right-making and wrong-making ones. I shall then argue that there is a very plausible position concerning the conditions under which an action can be morally wrong which entails the following asymmetry: there is a prima facie obligation not to bring into existence individuals whose lives are not worth living, but there is no corresponding obligation to create additional individuals whose lives would be worth living.

  1. Cerebral asymmetries: complementary and independent processes.

    Directory of Open Access Journals (Sweden)

    Gjurgjica Badzakova-Trajkov

    Full Text Available Most people are right-handed and left-cerebrally dominant for speech, leading historically to the general notion of left-hemispheric dominance, and more recently to genetic models proposing a single lateralizing gene. This hypothetical gene can account for higher incidence of right-handers in those with left cerebral dominance for speech. It remains unclear how this dominance relates to the right-cerebral dominance for some nonverbal functions such as spatial or emotional processing. Here we use functional magnetic resonance imaging with a sample of 155 subjects to measure asymmetrical activation induced by speech production in the frontal lobes, by face processing in the temporal lobes, and by spatial processing in the parietal lobes. Left-frontal, right-temporal, and right-parietal dominance were all intercorrelated, suggesting that right-cerebral biases may be at least in part complementary to the left-hemispheric dominance for language. However, handedness and parietal asymmetry for spatial processing were uncorrelated, implying independent lateralizing processes, one producing a leftward bias most closely associated with handedness, and the other a rightward bias most closely associated with spatial attention.

  2. On facial asymmetry and self-perception.

    Science.gov (United States)

    Lu, Stephen M; Bartlett, Scott P

    2014-06-01

    Self-perception has been an enduring human concern since ancient times and remains a significant component of the preoperative and postoperative consultation. Despite modern technological attempts to reproduce the first-hand experience, there is no perfect substitute for human, stereoscopic, three-dimensional vision in evaluating appearance. Nowadays, however, the primary tools available to a patient for examining his or her own appearance, particularly the face, are photographs and mirrors. Patients are often unaware of how cameras and photographs can distort and degrade image quality, leading to an inaccurate representation of true appearance. Everyone knows that mirrors reverse an image, left and right, and most people recognize their own natural facial asymmetry at some level. However, few realize that emotions are not only expressed unequally by the left and right sides of the face but also perceived unequally by others. The impact and effect of this "facedness" is completely reversed by mirrors, potentially creating a significant discrepancy between what a patient perceives of himself or herself and what the surgeon or other third party sees. This article ties together the diverse threads leading to this problem and suggests several ways of mitigating the issue through technology and patient counseling.

  3. CP asymmetries in Strange Baryon Decays

    Science.gov (United States)

    Bigi, I. I.; Kang, Xian-Wei; Li, Hai-Bo

    2018-01-01

    While indirect and direct CP violation (CPV) has been established in the decays of strange and beauty mesons, no CPV has yet been found for baryons. There are different paths to finding CP asymmetry in the decays of strange baryons; they are all highly non-trivial. The HyperCP Collaboration has probed CPV in the decays of single Ξ and Λ [1]. We discuss future lessons from {{{e}}}+{{{e}}}- collisions at BESIII/BEPCII: probing decays of pairs of strange baryons, namely Λ, Σ and Ξ. Realistic goals are to learn about non-perturbative QCD. One can hope to find CPV in the decays of strange baryons; one can also dream of finding the impact of New Dynamics. We point out that an important new era will start with the BESIII/BEPCII data accumulated by the end of 2018. This also supports new ideas to trigger {{J}}/{{\\psi }}\\to \\bar{{{Λ }}}{{Λ }} at the LHCb collaboration. Supported by National Science Foundation (PHY-1520966), National Natural Science Foundation of China (11335009, 11125525), Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (U1532257), the National Key Basic Research Program of China (2015CB856700), Key Research Program of Frontier Sciences, CAS, (QYZDJ-SSW-SLH003), XWK’s work is also supported by MOST (Taiwan) (104-2112-M-001-022)

  4. The Lateralizing Asymmetry of Adrenal Adenomas

    Science.gov (United States)

    Hao, Meng; Lopez, Diana; Luque-Fernandez, Miguel Angel; Cote, Kathryn; Newfield, Jessica; Connors, Molly; Vaidya, Anand

    2018-01-01

    Abstract Context It is presumed that the incidence of adrenal adenomas is symmetric between the left and right adrenal gland; however, anecdotal observations suggest a potential lateralizing asymmetry. Objective To investigate the symmetry in detection of adrenal adenomas and relevance to patient care. Design Cross-sectional and longitudinal studies. Population and Setting One thousand three hundred seventy-six patients with abdominal computed tomography or magnetic resonance imaging demonstrating benign-appearing adrenal adenomas. Main Outcome Location and size of adrenal adenomas. Results Left-sided adenomas were discovered in 65% of patients, right-sided in 21%, and bilateral adenomas in 14%. Among unilateral adenomas, 75% were left-sided. Left-sided adenomas were more prevalent than right-sided adenomas in each size category except the largest: Adrenal adenomas are substantially more likely to be identified on the left adrenal than the right. This observation may be due to detection bias attributed to the location of the right adrenal, which may preclude identification of right-sided adenomas until they are substantially larger. These findings suggest the potential for an underrecognition of right-sided adenomas that may also impair the accurate detection of bilateral adrenal diseases. PMID:29644340

  5. Impact of rheological layering on rift asymmetry

    Science.gov (United States)

    Jaquet, Yoann; Schmalholz, Stefan M.; Duretz, Thibault

    2015-04-01

    Although numerous models of rift formation have been proposed, what triggers asymmetry of rifted margins remains unclear. Parametrized material softening is often employed to induce asymmetric fault patterns in numerical models. Here, we use thermo-mechanical finite element models that allow softening via thermal weakening. We investigate the importance of lithosphere rheology and mechanical layering on rift morphology. The numerical code is based on the MILAMIN solver and uses the Triangle mesh generator. Our model configuration consists of a visco-elasto-platic layered lithosphere comprising either (1) only one brittle-ductile transition (in the mantle) or (2) three brittle-ductile transitions (one in the upper crust, one in the lower crust and one in the mantle). We perform then two sets of simulations characterized by low and high extensional strain rates (5*10-15 s-1, 2*10-14 s-1). The results show that the extension of a lithosphere comprising only one brittle-ductile transition produces a symmetric 'neck' type rift. The upper and lower crusts are thinned until the lithospheric mantle is exhumed to the seafloor. A lithosphere containing three brittle-ductile transitions favors strain localization. Shear zones at different horizontal locations and generated in the brittle levels of the lithosphere get connected by the weak ductile layers. The results suggest that rheological layering of the lithosphere can be a reason for the generation of asymmetric rifting and subsequent rift morphology.

  6. Asymmetries of the solar Ca II lines

    International Nuclear Information System (INIS)

    Heasley, J.N.

    1975-01-01

    A theoretical study of the influence of propagating acoustic pulses in the solar chromosphere upon the line profiles of the Ca II resonance and infrared triplet lines has been made. The major objective has been to explain the observed asymmetries seen in the cores of the H and K lines and to predict the temporal behavior of the infrared lines caused by passing acoustic or shock pulses. The velocities in the pulses, calculated from weak shock theory, have been included consistently in the non-LTE calculations. The results of the calculations show that these lines are very sensitive to perturbations in the background atmosphere caused by the pulses. Only minor changes in the line shapes result from including the velocities consistently in the line source function calculations. The qualitative changes in the line profiles vary markedly with the strength of the shock pulses. The observed differences in the K line profiles seen on the quiet Sun can be explained in terms of a spectrum of pulses with different wavelengths and initial amplitudes in the photosphere. (Auth.)

  7. The baryon asymmetry and CPT invariance in the early universe

    International Nuclear Information System (INIS)

    Barshay, S.

    1981-01-01

    We discuss, and give a definite, simple phenomenological example, of the possibility that the baryon asymmetry is related to a failure of CPT invariance for a brief time interval at the origin of the universe. (orig.)

  8. Axial asymmetry, finite particle number and the IBA

    International Nuclear Information System (INIS)

    Casten, R.F.

    1984-01-01

    Although the IBA-1 contains no solutions corresponding to a rigid triaxial shape, it does contain an effective asymmetry. This arises from zero point motion in a γ-soft potential leading to a non-zero mean or rms γ. Three aspects of this feature will be discussed: (1) The relation between IBA-1 calculations and the corresponding γ. This point is developed in the context of the Consistent Q Formalism (CQF) of the IBA. (2) The dependence of this asymmetry on boson number, N, and the exploitation of this dependence to set limits on both the relative and absolute values of N for deformed nuclei. (3) The relation between this asymmetry and the triaxiality arising from the introduction of cubic terms into the IBA Hamiltonian. Various observables will be inspected in order both to determine their sensitivity to these two structural features and to explore empirical ways of distinguishing which origin of asymmetry applies in any given nucleus. 16 references

  9. Birth order and fluctuating asymmetry: a first look.

    Science.gov (United States)

    Lalumière, M L; Harris, G T; Rice, M E

    1999-01-01

    We investigated the hypothesis that maternal immunoreactivity to male-specific features of the foetus can increase developmental instability. We predicted that the participants' number of older brothers would be positively related to the fluctuating asymmetry of ten bilateral morphological traits. The participants were 40 adult male psychiatric patients and 31 adult male hospital employees. Consistent with the hypothesis, the participants' number of older brothers--but not number of older sisters, younger brothers or younger sisters--was positively associated with fluctuating asymmetry. The patients had significantly larger fluctuating asymmetry scores and tended to have more older brothers than the employees, but the positive relationship between the number of older brothers and fluctuating asymmetry was observed in both groups. PMID:10643079

  10. Quantitative-genetic analysis of wing form and bilateral asymmetry ...

    Indian Academy of Sciences (India)

    Unknown

    lines; Procrustes analysis; wing shape; wing size. ... Models of stochastic gene expression pre- dict that intrinsic noise ... Quantitative parameters of wing size and shape asymmetries ..... the residuals of a regression on centroid size produced.

  11. Amplitude and polarization asymmetries in a ring laser

    Science.gov (United States)

    Campbell, L. L.; Buholz, N. E.

    1971-01-01

    Asymmetric amplitude effects between the oppositely directed traveling waves in a He-Ne ring laser are analyzed both theoretically and experimentally. These effects make it possible to detect angular orientations of an inner-cavity bar with respect to the plane of the ring cavity. The amplitude asymmetries occur when a birefringent bar is placed in the three-mirror ring cavity, and an axial magnetic field is applied to the active medium. A simplified theoretical analysis is performed by using a first order perturbation theory to derive an expression for the polarization of the active medium, and a set of self-consistent equations are derived to predict threshold conditions. Polarization asymmetries between the oppositely directed waves are also predicted. Amplitude asymmetries similar in nature to those predicted at threshold occur when the laser is operating in 12-15 free-running modes, and polarization asymmetry occurs simultaneously.

  12. The asymmetry of tourist images for the international cross border ...

    African Journals Online (AJOL)

    The asymmetry of tourist images for the international cross border three- ... of images promotion strategy, which is called “positioning” in Marketing. ... Keywords: tourism, tourist brand, Chita region, Mongolia, tourist and recreational activities ...

  13. Effect of Information Asymmetry and Relationship Lending on ...

    African Journals Online (AJOL)

    Effect of Information Asymmetry and Relationship Lending on Financial ... from small- business- friendly financial institutions, hypotheses postulated by the ... a model of transaction costs of financial contracting that put into consideration the ...

  14. Flavor versus mass eigenstates in neutrino asymmetries: implications for cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Barenboim, Gabriela [Universitat de Valencia-CSIC, Departament de Fisica Teorica y IFIC, Burjassot (Spain); Kinney, William H. [University at Buffalo, Department of Physics, Buffalo, NY (United States); Park, Wan-Il [Universitat de Valencia-CSIC, Departament de Fisica Teorica y IFIC, Burjassot (Spain); Chonbuk National University, Division of Science Education and Institute of Fusion Science, Jeonju (Korea, Republic of)

    2017-09-15

    We show that, if they exist, lepton number asymmetries (L{sub α}) of neutrino flavors should be distinguished from the ones (L{sub i}) of mass eigenstates, since Big Bang Nucleosynthesis (BBN) bounds on the flavor eigenstates cannot be directly applied to the mass eigenstates. Similarly, Cosmic Microwave Background (CMB) constraints on the mass eigenstates do not directly constrain flavor asymmetries. Due to the difference of mass and flavor eigenstates, the cosmological constraint on the asymmetries of neutrino flavors can be much stronger than the conventional expectation, but they are not uniquely determined unless at least the asymmetry of the heaviest neutrino is well constrained. The cosmological constraint on L{sub i} for a specific case is presented as an illustration. (orig.)

  15. Hemispheric asymmetry in the influence of language on visual perception.

    Science.gov (United States)

    Sun, Yanliang; Cai, Yongchun; Lu, Shena

    2015-07-01

    Many studies have shown that language can affect visual perception; however, our understanding of the neural basis of linguistic influence is inadequate. This can be investigated by examining the hemispheric asymmetry of linguistic influence. The left and right hemispheres are dominant in close and distant semantic processing, respectively. In this study, we investigated whether the hemispheric asymmetry of semantic processing led to hemispheric asymmetry for concept priming on the detection of objects degraded by continuous flash suppression. We combined a priming paradigm with the divided visual field paradigm and used continuous flash suppression, which renders objects invisible. The results indicated that the hemispheric asymmetry of semantic processing led to a right lateralization in the influence of more abstract concepts on visual perception. The lateralization of brain connectomes may be the underlying neural basis of this effect. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. A voxel-based approach to gray matter asymmetries.

    Science.gov (United States)

    Luders, E; Gaser, C; Jancke, L; Schlaug, G

    2004-06-01

    Voxel-based morphometry (VBM) was used to analyze gray matter (GM) asymmetries in a large sample (n = 60) of male and female professional musicians with and without absolute pitch (AP). We chose to examine these particular groups because previous studies using traditional region-of-interest (ROI) analyses have shown differences in hemispheric asymmetry related to AP and gender. Voxel-based methods may have advantages over traditional ROI-based methods since the analysis can be performed across the whole brain with minimal user bias. After determining that the VBM method was sufficiently sensitive for the detection of differences in GM asymmetries between groups, we found that male AP musicians were more leftward lateralized in the anterior region of the planum temporale (PT) than male non-AP musicians. This confirmed the results of previous studies using ROI-based methods that showed an association between PT asymmetry and the AP phenotype. We further observed that male non-AP musicians revealed an increased leftward GM asymmetry in the postcentral gyrus compared to female non-AP musicians, again corroborating results of a previously published study using ROI-based methods. By analyzing hemispheric GM differences across our entire sample, we were able to partially confirm findings of previous studies using traditional morphometric techniques, as well as more recent, voxel-based analyses. In addition, we found some unusually pronounced GM asymmetries in our musician sample not previously detected in subjects unselected for musical training. Since we were able to validate gender- and AP-related brain asymmetries previously described using traditional ROI-based morphometric techniques, the results of our analyses support the use of VBM for examinations of GM asymmetries.

  17. New physics in CP asymmetries and rare B decays

    International Nuclear Information System (INIS)

    Gronau, M.; London, D.

    1997-01-01

    We review and update the effects of physics beyond the standard model on CP asymmetries in B decays. These asymmetries can be significantly altered if there are important new-physics contributions to B q 0 -B q 0 mixing. This same new physics will, therefore, also contribute to rare, flavor-changing B decays. Through a study of such decays, we show that it is possible to partially distinguish the different models of new physics. copyright 1997 The American Physical Society

  18. Tuning piezoresistive transduction in nanomechanical resonators by geometrical asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Llobet, J.; Sansa, M.; Lorenzoni, M.; Pérez-Murano, F., E-mail: francesc.perez@csic.es [Institut de Microelectrònica de Barcelona (IMB-CNM CSIC), Campus UAB, 08193 Bellaterra (Spain); Borrisé, X. [Institut Català de Nanociència i Nanotecnologia (ICN2), Campus UAB, 08193 Bellaterra Spain (Spain); San Paulo, A. [Instituto de Microelectrónica de Madrid (IMM-CSIC), 28760 Tres Cantos, Madrid (Spain)

    2015-08-17

    The effect of geometrical asymmetries on the piezoresistive transduction in suspended double clamped beam nanomechanical resonators is investigated. Tapered silicon nano-beams, fabricated using a fast and flexible prototyping method, are employed to determine how the asymmetry affects the transduced piezoresistive signal for different mechanical resonant modes. This effect is attributed to the modulation of the strain in pre-strained double clamped beams, and it is confirmed by means of finite element simulations.

  19. Asymmetry of the structural brain connectome in healthy older adults.

    Directory of Open Access Journals (Sweden)

    Leonardo eBonilha

    2014-01-01

    Full Text Available Background: It is now possible to map neural connections in vivo across the whole brain (i.e., the brain connectome. This is a promising development in neuroscience since many health and disease processes are believed to arise from the architecture of neural networks.Objective: To describe the normal range of hemispheric asymmetry in structural connectivity in healthy older adults.Methods: We obtained high-resolution structural magnetic resonance images (MRI from 17 healthy older adults. For each subject, the brain connectome was reconstructed by parcelating the probabilistic map of gray matter into anatomically defined regions of interested (ROIs. White matter fiber tractography was reconstructed from diffusion tensor imaging and streamlines connecting gray matter ROIs were computed. Asymmetry indices were calculated regarding ROI connectivity (representing the sum of connectivity weight of each cortical ROI and for regional white matter links. All asymmetry measures were compared to a normal distribution with mean=0 through one sample t-tests.Results: Leftward cortical ROI asymmetry was observed in medial temporal, dorsolateral frontal and occipital regions. Rightward cortical ROI asymmetry was observed in middle temporal and orbito-frontal regions. Link-wise asymmetry revealed stronger connections in the left hemisphere between the medial temporal, anterior and posterior peri-Sylvian and occipito-temporal regions. Rightward link asymmetry was observed in lateral temporal, parietal and dorsolateral frontal connections.Conclusions: We postulate that asymmetry of specific connections may be related to functional hemispheric organization. This study may provide reference for future studies evaluating the architecture of the connectome in health and disease processes in senior individuals.

  20. Single spin asymmetries and the spin of the proton

    International Nuclear Information System (INIS)

    Dominguez Z, G.; Herrera C, G.

    2000-01-01

    We study the spin asymmetries of inclusive π + , π 0 , π - , η and γ production in the interaction of a polarized with a non polarized proton, in the frame of a two component model. Particle production in the model is assumed to consist of a conventional QCD fragmentation process plus a recombination mechanism. The presence of Thomas precession in the recombination process seems to be responsible for the production spin asymmetry. (Author) 12 refs., 8 figs

  1. Collins Fragmentation and the Single Transverse Spin Asymmetry

    OpenAIRE

    Yuan, Feng; Zhou, Jian

    2009-01-01

    We study the Collins mechanism for the single transverse spin asymmetry in the collinear factorization approach. The correspondent twist-three fragmentation function is identified. We show that the Collins function calculated in this approach is universal. We further examine its contribution to the single transverse spin asymmetry of semi-inclusive hadron production in deep inelastic scattering and demonstrate that the transverse momentum dependent and twist-three collinear approaches are con...

  2. Polarization asymmetries and gauge theory interactions at short distances

    International Nuclear Information System (INIS)

    Craigie, N.S.

    1983-01-01

    In this talk, we give the arguments as to why spin asymmetries test fundamental properties of the underlying gauge theories of elementary particles, concentrating mainly on electro-weak and QCD interactions, but also looking at the future and possible signatures for supersymmetric strong interactions. We also mention briefly the role helicity asymmetry measurements can play as regards higher order corrections, including higher twist, in QCD. (orig./HSI)

  3. Manufacture of Strand Board Bonded with Disposal Expanded Polystyrene as Binder

    OpenAIRE

    Hermawan, Andi; Ohuchi, Takeshi; Fujimoto, Noboru; 大内, 毅; 藤本, 登留

    2010-01-01

    The objective of this study was to evaluate the physical and mechanical properties of strand board bonded with disposal expanded polystyrene (EPS) as binder. The strand board was manufactured using strand made from Douglas-fir beams selected from construction scrap wood. The strands were oriented, and two types of three-layer (face-core-face) strand board were manufactured: one in which the board bounded with only disposal EPS (P board), and the other in which the board bonded with disposal...

  4. Ketahanan Papan Unting (Oriented Strand Board) terhadap Serangan Rayap Tanah dan Rayap Kayu Kering

    OpenAIRE

    Gea, Bud diman

    2011-01-01

    Oriented strand board is panel of wood raw material from which strand composed of cross and upright structure. In order to oriented strand board can be used for interior and exterior needs, than necessary to be applied various thenology of quality improvement like durabelities and endurance of oriented strand board. For it does found endurance oriented strand board from attack of ground termite and wood dry termite, necessary doing grave yard trial and wood dry termite trial. This research ta...

  5. The Effect of Basepair Mismatch on DNA Strand Displacement.

    Science.gov (United States)

    Broadwater, D W Bo; Kim, Harold D

    2016-04-12

    DNA strand displacement is a key reaction in DNA homologous recombination and DNA mismatch repair and is also heavily utilized in DNA-based computation and locomotion. Despite its ubiquity in science and engineering, sequence-dependent effects of displacement kinetics have not been extensively characterized. Here, we measured toehold-mediated strand displacement kinetics using single-molecule fluorescence in the presence of a single basepair mismatch. The apparent displacement rate varied significantly when the mismatch was introduced in the invading DNA strand. The rate generally decreased as the mismatch in the invader was encountered earlier in displacement. Our data indicate that a single base pair mismatch in the invader stalls branch migration and displacement occurs via direct dissociation of the destabilized incumbent strand from the substrate strand. We combined both branch migration and direct dissociation into a model, which we term the concurrent displacement model, and used the first passage time approach to quantitatively explain the salient features of the observed relationship. We also introduce the concept of splitting probabilities to justify that the concurrent model can be simplified into a three-step sequential model in the presence of an invader mismatch. We expect our model to become a powerful tool to design DNA-based reaction schemes with broad functionality. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  6. Mercury exposure may influence fluctuating asymmetry in waterbirds.

    Science.gov (United States)

    Herring, Garth; Eagles-Smith, Collin A; Ackerman, Joshua T

    2017-06-01

    Variation in avian bilateral symmetry can be an indicator of developmental instability in response to a variety of stressors, including environmental contaminants. The authors used composite measures of fluctuating asymmetry to examine the influence of mercury concentrations in 2 tissues on fluctuating asymmetry within 4 waterbird species. Fluctuating asymmetry increased with mercury concentrations in whole blood and breast feathers of Forster's terns (Sterna forsteri), a species with elevated mercury concentrations. Specifically, fluctuating asymmetry in rectrix feather 1 was the most strongly correlated structural variable of those tested (wing chord, tarsus, primary feather 10, rectrix feather 6) with mercury concentrations in Forster's terns. However, for American avocets (Recurvirostra americana), black-necked stilts (Himantopus mexicanus), and Caspian terns (Hydroprogne caspia), the authors found no relationship between fluctuating asymmetry and either whole-blood or breast feather mercury concentrations, even though these species had moderate to elevated mercury exposure. The results indicate that mercury contamination may act as an environmental stressor during development and feather growth and contribute to fluctuating asymmetry of some species of highly contaminated waterbirds. Environ Toxicol Chem 2017;36:1599-1605. Published 2016 Wiley Periodicals Inc. on behalf of SETAC. This article is a US government work and, as such, is in the public domain in the United States of America. Published 2016 Wiley Periodicals Inc. on behalf of SETAC. This article is a US government work and, as such, is in the public domain in the United States of America.

  7. Mercury exposure may influence fluctuating asymmetry in waterbirds

    Science.gov (United States)

    Herring, Garth; Eagles-Smith, Collin A.; Ackerman, Joshua T.

    2017-01-01

    Variation in avian bilateral symmetry can be an indicator of developmental instability in response to a variety of stressors, including environmental contaminants. The authors used composite measures of fluctuating asymmetry to examine the influence of mercury concentrations in 2 tissues on fluctuating asymmetry within 4 waterbird species. Fluctuating asymmetry increased with mercury concentrations in whole blood and breast feathers of Forster's terns (Sterna forsteri), a species with elevated mercury concentrations. Specifically, fluctuating asymmetry in rectrix feather 1 was the most strongly correlated structural variable of those tested (wing chord, tarsus, primary feather 10, rectrix feather 6) with mercury concentrations in Forster's terns. However, for American avocets (Recurvirostra americana), black-necked stilts (Himantopus mexicanus), and Caspian terns (Hydroprogne caspia), the authors found no relationship between fluctuating asymmetry and either whole-blood or breast feather mercury concentrations, even though these species had moderate to elevated mercury exposure. The results indicate that mercury contamination may act as an environmental stressor during development and feather growth and contribute to fluctuating asymmetry of some species of highly contaminated waterbirds.

  8. The validity of individual frontal alpha asymmetry EEG neurofeedback.

    Science.gov (United States)

    Quaedflieg, C W E M; Smulders, F T Y; Meyer, T; Peeters, F; Merckelbach, H; Smeets, T

    2016-01-01

    Frontal asymmetry in alpha oscillations is assumed to be associated with psychopathology and individual differences in emotional responding. Brain-activity-based feedback is a promising tool for the modulation of cortical activity. Here, we validated a neurofeedback protocol designed to change relative frontal asymmetry based on individual alpha peak frequencies, including real-time average referencing and eye-correction. Participants (N = 60) were randomly assigned to a right, left or placebo neurofeedback group. Results show a difference in trainability between groups, with a linear change in frontal alpha asymmetry over time for the right neurofeedback group during rest. Moreover, the asymmetry changes in the right group were frequency and location specific, even though trainability did not persist at 1 week and 1 month follow-ups. On the behavioral level, subjective stress on the second test day was reduced in the left and placebo neurofeedback groups, but not in the right neurofeedback group. We found individual differences in trainability that were dependent on training group, with participants in the right neurofeedback group being more likely to change their frontal asymmetry in the desired direction. Individual differences in trainability were also reflected in the ability to change frontal asymmetry during the feedback. © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  9. Using ground reaction force to predict knee kinetic asymmetry following anterior cruciate ligament reconstruction.

    Science.gov (United States)

    Dai, B; Butler, R J; Garrett, W E; Queen, R M

    2014-12-01

    Asymmetries in sagittal plane knee kinetics have been identified as a risk factor for anterior cruciate ligament (ACL) re-injury. Clinical tools are needed to identify the asymmetries. This study examined the relationships between knee kinetic asymmetries and ground reaction force (GRF) asymmetries during athletic tasks in adolescent patients following ACL reconstruction (ACL-R). Kinematic and GRF data were collected during a stop-jump task and a side-cutting task for 23 patients. Asymmetry indices between the surgical and non-surgical limbs were calculated for GRF and knee kinetic variables. For the stop-jump task, knee kinetics asymmetry indices were correlated with all GRF asymmetry indices (P kinetic asymmetry indices were correlated with the peak propulsion vertical GRF and vertical GRF impulse asymmetry indices (P kinetic asymmetries and therefore may assist in optimizing rehabilitation outcomes and minimizing re-injury rates. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Identification of cis-acting elements on positive-strand subgenomic mRNA required for the synthesis of negative-strand counterpart in bovine coronavirus.

    Science.gov (United States)

    Yeh, Po-Yuan; Wu, Hung-Yi

    2014-07-30

    It has been demonstrated that, in addition to genomic RNA, sgmRNA is able to serve as a template for the synthesis of the negative-strand [(-)-strand] complement. However, the cis-acting elements on the positive-strand [(+)-strand] sgmRNA required for (-)-strand sgmRNA synthesis have not yet been systematically identified. In this study, we employed real-time quantitative reverse transcription polymerase chain reaction to analyze the cis-acting elements on bovine coronavirus (BCoV) sgmRNA 7 required for the synthesis of its (-)-strand counterpart by deletion mutagenesis. The major findings are as follows. (1) Deletion of the 5'-terminal leader sequence on sgmRNA 7 decreased the synthesis of the (-)-strand sgmRNA complement. (2) Deletions of the 3' untranslated region (UTR) bulged stem-loop showed no effect on (-)-strand sgmRNA synthesis; however, deletion of the 3' UTR pseudoknot decreased the yield of (-)-strand sgmRNA. (3) Nucleotides positioned from -15 to -34 of the sgmRNA 7 3'-terminal region are required for efficient (-)-strand sgmRNA synthesis. (4) Nucleotide species at the 3'-most position (-1) of sgmRNA 7 is correlated to the efficiency of (-)-strand sgmRNA synthesis. These results together suggest, in principle, that the 5'- and 3'-terminal sequences on sgmRNA 7 harbor cis-acting elements are critical for efficient (-)-strand sgmRNA synthesis in BCoV.

  11. A voxel-based asymmetry study of the relationship between hemispheric asymmetry and language dominance in Wada tested patients.

    Science.gov (United States)

    Keller, Simon S; Roberts, Neil; Baker, Gus; Sluming, Vanessa; Cezayirli, Enis; Mayes, Andrew; Eldridge, Paul; Marson, Anthony G; Wieshmann, Udo C

    2018-03-23

    Determining the anatomical basis of hemispheric language dominance (HLD) remains an important scientific endeavor. The Wada test remains the gold standard test for HLD and provides a unique opportunity to determine the relationship between HLD and hemispheric structural asymmetries on MRI. In this study, we applied a whole-brain voxel-based asymmetry (VBA) approach to determine the relationship between interhemispheric structural asymmetries and HLD in a large consecutive sample of Wada tested patients. Of 135 patients, 114 (84.4%) had left HLD, 10 (7.4%) right HLD, and 11 (8.2%) bilateral language representation. Fifty-four controls were also studied. Right-handed controls and right-handed patients with left HLD had comparable structural brain asymmetries in cortical, subcortical, and cerebellar regions that have previously been documented in healthy people. However, these patients and controls differed in structural asymmetry of the mesial temporal lobe and a circumscribed region in the superior temporal gyrus, suggesting that only asymmetries of these regions were due to brain alterations caused by epilepsy. Additional comparisons between patients with left and right HLD, matched for type and location of epilepsy, revealed that structural asymmetries of insula, pars triangularis, inferior temporal gyrus, orbitofrontal cortex, ventral temporo-occipital cortex, mesial somatosensory cortex, and mesial cerebellum were significantly associated with the side of HLD. Patients with right HLD and bilateral language representation were significantly less right-handed. These results suggest that structural asymmetries of an insular-fronto-temporal network may be related to HLD. © 2018 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

  12. DNA turnover and strand breaks in Escherichia coli

    International Nuclear Information System (INIS)

    Hanawalt, P.; Grivell, A.; Nakayama, H.

    1975-01-01

    The extent of DNA turnover has been measured in a dnaB mutant of Escherichia coli, temperature sensitive for semiconservative DNA replication. At the nonpermissive temperature about 0.02 percent of the deoxynucleotides in DNA are exchanged per generation period. This turnover rate is markedly depressed in the presence of rifampicin. During thymine starvation strand breaks accumulate in the DNA of E. coli strains that are susceptible to thymineless death. Rifampicin suppresses the appearance of these breaks, consistent with our hypothesis that transcription may be accompanied by repairable single-strand breaks in DNA. DNA turnover is enhanced severalfold in strands containing 5-bromodeoxyuridine in place of thymidine, possibly because the analog (or the deoxyuridine, following debromination) is sometimes recognized and excised

  13. Stem cell identity and template DNA strand segregation.

    Science.gov (United States)

    Tajbakhsh, Shahragim

    2008-12-01

    The quest for stem cell properties to distinguish their identity from that of committed daughters has led to a re-investigation of the notion that DNA strands are not equivalent, and 'immortal' DNA strands are retained in stem cells whereas newly replicated DNA strands segregate to the differentiating daughter cell during mitosis. Whether this process occurs only in stem cells, and also in all tissues, remains unclear. That individual chromosomes can be also partitioned non-randomly raises the question if this phenomenon is related to the immortal DNA hypothesis, and it underscores the need for high-resolution techniques to observe these events empirically. Although initially postulated as a mechanism to avoid DNA replication errors, alternative views including epigenetic regulation and sister chromatid silencing may provide insights into this process.

  14. Transmission pricing and stranded costs in the electric power industry

    International Nuclear Information System (INIS)

    Baumol, W.J.; Sidak, J.G.

    1995-09-01

    Stranded costs are those costs that electric utilities are currently permitted to recover through their rates but whose recovery may be impeded or prevented by the advent of competition in the industry. Estimates of these costs run from the tens to the hundreds of billions of dollars. Should regulators permit utilities to recover stranded costs while they take steps to promote competition in the electric power industry. William Baumol and J. Gregory Sidak argue that answer to that question should be yes.The authors show that a transmission price, the price for sending electricity over the transmission grid, can be determined in a manner that is compatible with economic efficiency and clearly neutral in its effects upon all competitors in electricity generation. A correctly constructed regime of transmission pricing may in fact achieve the efficiency and equity goals that justify the recovery of stranded costs

  15. Informal Science learning in PIBID: identifying and interpreting the strands

    Directory of Open Access Journals (Sweden)

    Thomas Barbosa Fejolo

    2013-10-01

    Full Text Available This paper presents a research on informal Science learning in the context of the Institutional Scholarship Program Initiation to Teaching (PIBID. We take as reference the strands of informal Science learning (FAC, representing six dimensions of learning, they are: 1 Development of interest in Science; 2 Understanding of scientific knowledge; 3 Engaging in scientific reasoning; 4 Reflection on Science; 5 Engagement in scientific practice; 6 Identification with Science. For the lifting data, it was used the filming record of the interactions and dialogues of undergraduate students while performing activities of Optical Spectroscopy in the laboratory. Based on the procedures of content analysis and interpretations through communication, we investigate which of the six strands were present during the action of the students in activities. As a result we have drawn a learning profile for each student by distributing communications in different strands of informal Science learning.

  16. Development of Nb3Sn strands for ITER in Japan

    International Nuclear Information System (INIS)

    Isono, T.; Nunoya, Y.; Matsui, K.; Nabara, Y.; Koizumi, N.; Takahashi, Y.; Okuno, K.

    2007-01-01

    Nb 3 Sn strands for ITER Toroidal Field (TF) coils and Central Solenoids (CS) are required to have both high current density (Jc) and low hysteresis loss. The required Jc at 12 T, 4.2 K and no external strain is lager than 700 A/mm 2 for bronze processed strand and lager than 800 A/mm 2 for internal tin processed one at 12 T, 4.2 K and no external strain. Upper limit of hysteresis loss is 1,000 mJ/cm 3 at 4.2 K and a cycle of ±3 T. Outer diameter is 0.82 mm and 0.83 mm for TF coils and CS, respectively. Area ratio of copper to non copper is one and outer surface is Cr plated. Japan will procure 25% of Nb 3 Sn for ITER TF coils and 100% for ITER CS. There are four Nb 3 Sn strand suppliers in Japan; three of them use bronze process and the other uses internal tin process. For bronze processed strand, increase Jc was achieved by using bronze with high tin content of 15 to 16%. To keep productivity while using the harder bronze with high tin content, Nb is used for barrier in place of Ta. The material is expected to have better adhesion to other materials such as bronze and copper. For internal tin process, size of modules, each of which has a tin rod and a lot of Nb filaments embedded in a copper cylinder, is reduced, while total amount of tin increase in order to satisfy both required high Jc and low hysteresis loss. Each supplier fabricated a strand of more than 0.1 ton for TF coils and succeeded to develop a strand satisfying the ITER requirements of Jc and hysteresis loss. (authors)

  17. Genetic transformation of Neisseria gonorrhoeae shows a strand preference

    OpenAIRE

    Duffin, Paul M.; Seifert, H. Steven

    2012-01-01

    Natural transformation is the main means of horizontal genetic exchange in the obligate human pathogen Neisseria gonorrhoeae. Neisseria spp. have been shown to preferentially take up and transform their own DNA by recognizing a non-palindromic 10 or 12 nucleotide DNA uptake sequence (DUS10 or DUS12). We investigated the ability of the DUS12 to enhance single-stranded DNA (ssDNA) transformation. Given the non-palindromic nature of the DUS12, we tested whether both strands of the DUS equally en...

  18. Industry participation workshop: Chromium electroplating of superconductor strand. Proceedings

    International Nuclear Information System (INIS)

    1994-01-01

    The primary objective of the workshop was to inform US plating vendors about the opportunity to participate in the effort on Cr plating of large quantities of superconducting wires required for the ITER and the TPX projects and DOE's interest in developing several reliable and high quality suppliers of Chromium plating services for the superconducting strand industry. The objective was also to inform plating vendors about the Cr plating technology developed in LLNL and invite interested plating vendors to get the technology. Finally the workshop was intended to inform the plating vendors about the plan to get verification of capability of two to four vendors for Cr plating of superconducting strands

  19. Nucleic Acid Analogue Induced Transcription of Double Stranded DNA

    DEFF Research Database (Denmark)

    1998-01-01

    RNA is transcribed from a double stranded DNA template by forming a complex by hybridizing to the template at a desired transcription initiation site one or more oligonucleic acid analogues of the PNA type capable of forming a transcription initiation site with the DNA and exposing the complex...... to the action of a DNA dependant RNA polymerase in the presence of nucleoside triphosphates. Equal length transcripts may be obtained by placing a block to transcription downstream from the initiation site or by cutting the template at such a selected location. The initiation site is formed by displacement...... of one strand of the DNA locally by the PNA hybridization....

  20. Conformal geometry and invariants of 3-strand Brownian braids

    International Nuclear Information System (INIS)

    Nechaev, Sergei; Voituriez, Raphael

    2005-01-01

    We propose a simple geometrical construction of topological invariants of 3-strand Brownian braids viewed as world lines of 3 particles performing independent Brownian motions in the complex plane z. Our construction is based on the properties of conformal maps of doubly-punctured plane z to the universal covering surface. The special attention is paid to the case of indistinguishable particles. Our method of conformal maps allows us to investigate the statistical properties of the topological complexity of a bunch of 3-strand Brownian braids and to compute the expectation value of the irreducible braid length in the non-Abelian case

  1. Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.

    Science.gov (United States)

    Löser, Dana A; Shibata, Atsushi; Shibata, Akiko K; Woodbine, Lisa J; Jeggo, Penny A; Chalmers, Anthony J

    2010-06-01

    As single agents, chemical inhibitors of poly(ADP-ribose) polymerase (PARP) are nontoxic and have clinical efficacy against BRCA1- and BRCA2-deficient tumors. PARP inhibitors also enhance the cytotoxicity of ionizing radiation and alkylating agents but will only improve clinical outcomes if tumor sensitization exceeds effects on normal tissues. It is unclear how tumor DNA repair proficiency affects the degree of sensitization. We have previously shown that the radiosensitizing effect of PARP inhibition requires DNA replication and will therefore affect rapidly proliferating tumors more than normal tissues. Because many tumors exhibit defective DNA repair, we investigated the impact of double-strand break (DSB) repair integrity on the sensitizing effects of the PARP inhibitor olaparib. Sensitization to ionizing radiation and the alkylating agent methylmethane sulfonate was enhanced in DSB repair-deficient cells. In Artemis(-/-) and ATM(-/-) mouse embryo fibroblasts, sensitization was replication dependent and associated with defective repair of replication-associated damage. Radiosensitization of Ligase IV(-/-) mouse embryo fibroblasts was independent of DNA replication and is explained by inhibition of "alternative" end joining. After methylmethane sulfonate treatment, PARP inhibition promoted replication-independent accumulation of DSB, repair of which required Ligase IV. Our findings predict that the sensitizing effects of PARP inhibitors will be more pronounced in rapidly dividing and/or DNA repair defective tumors than normal tissues and show their potential to enhance the therapeutic ratio achieved by conventional DNA-damaging agents.

  2. Karyotipic asymmetry of both wild and cultivated species of Pennisetum

    Directory of Open Access Journals (Sweden)

    Vânia Helena Techio

    2010-01-01

    Full Text Available This study aimed the establishment of the relation between karyotipic asymmetry values obtained for different accessions of both wild and cultivated species of Pennisetum from Germplasm Bank of Embrapa Gado de Leite/Juiz de Fora-Minas Gerais State, Brazil. Conventional cell cycle synchronization protocols and Feulgen staining method were used to obtain metaphases plates. The wild-type accessions corresponded to the species P. setosum (2n=6x=54, P. nervosum (2n=4x=36, and P. orientale (2n=4x=36, and the cultivated to P. purpureum (2n=4x=28 and P. glaucum (2n=2x=14. No significant difference was found for the total length of chromosomes (p>0.05 among the species. The analysis of intra-chromosomal asymmetry (A1 and inter-chromosomal asymmetry (A2 has shown that P. setosum has a tendency to chromosome asymmetry. P. nervosum, P. orientale, and P. purpureum have presented an intermediary level of asymmetry and P. glaucum, low asymmetry. Considering Stebbins criteria, the karyotype of P. glaucum and those from the three wild species fitted into the category 1A-symmetrical. With regard to P. purpureum, karyotypes of the accessions BAGs 54, 65 and 91 fitted into the category 2B and the other two genotypes (BAGs 63 and 75 fitted into the 1A. Comparison between the karyotype classification according to the inter- and intra-chromosomal asymmetry and Stebbins methodologies revealed that this last one alone was not able to detect small variations between karyotypes of the taxa closely related.

  3. Cosmological evidence for leptonic asymmetry after Planck

    Energy Technology Data Exchange (ETDEWEB)

    Caramete, A.; Popa, L.A., E-mail: acaramete@spacescience.ro, E-mail: lpopa@spacescience.ro [Institute of Space Science, 409 Atomistilor Street, Magurele, Ilfov 077125 (Romania)

    2014-02-01

    Recently, the PLANCK satellite found a larger and most precise value of the matter energy density, that impacts on the present values of other cosmological parameters such as the Hubble constant H{sub 0}, the present cluster abundances S{sub 8}, and the age of the Universe t{sub U}. The existing tension between PLANCK determination of these parameters in the frame of the base ΛCDM model and their determination from other measurements generated lively discussions, one possible interpretation being that some sources of systematic errors in cosmological measurements are not completely understood. An alternative interpretation is related to the fact that the CMB observations, that probe the high redshift Universe are interpreted in terms of cosmological parameters at present time by extrapolation within the base ΛCDM model that can be inadequate or incomplete. In this paper we quantify this tension by exploring several extensions of the base ΛCDM model that include the leptonic asymmetry. We set bounds on the radiation content of the Universe and neutrino properties by using the latest cosmological measurements, imposing also self-consistent BBN constraints on the primordial helium abundance. For all asymmetric cosmological models we find the preference of cosmological data for smaller values of active and sterile neutrino masses. This increases the tension between cosmological and short baseline neutrino oscillation data that favors a sterile neutrino with the mass of around 1 eV. For the case of degenerate massive neutrinos, we find that the discrepancies with the local determinations of H{sub 0}, and t{sub U} are alleviated at ∼ 1.3σ level while S{sub 8} is in agreement with its determination from CFHTLenS survey data at ∼ 1σ and with the prediction of cluster mass-observation relation at ∼ 0.5σ. We also find 2σ statistical preference of the cosmological data for the leptonic asymmetric models involving three massive neutrino species and neutrino direct

  4. Prediction of Gap Asymmetry in Differential Micro Accelerometers

    Directory of Open Access Journals (Sweden)

    Xiaoping He

    2012-05-01

    Full Text Available Gap asymmetry in differential capacitors is the primary source of the zero bias output of force-balanced micro accelerometers. It is also used to evaluate the applicability of differential structures in MEMS manufacturing. Therefore, determining the asymmetry level has considerable significance for the design of MEMS devices. This paper proposes an experimental-theoretical method for predicting gap asymmetry in differential sensing capacitors of micro accelerometers. The method involves three processes: first, bi-directional measurement, which can sharply reduce the influence of the feedback circuit on bias output, is proposed. Experiments are then carried out on a centrifuge to obtain the input and output data of an accelerometer. Second, the analytical input-output relationship of the accelerometer with gap asymmetry and circuit error is theoretically derived. Finally, the prediction methodology combines the measurement results and analytical derivation to identify the asymmetric error of 30 accelerometers fabricated by DRIE. Results indicate that the level of asymmetry induced by fabrication uncertainty is about ±5 × 10−2, and that the absolute error is about ±0.2 µm under a 4 µm gap.

  5. Left-right asymmetry in neutrino-produced hadron jets

    International Nuclear Information System (INIS)

    Ballagh, H.C.; Bingham, H.H.; Lawry, T.J.; Lys, J.; Lynch, G.R.; Sokoloff, M.D.; Stevenson, M.L.; Huson, F.R.; Schmidt, E.; Smart, W.; Treadwell, E.; Cence, R.J.; Harris, F.A.; Jones, M.D.; Koide, A.; Peters, M.W.; Peterson, V.Z.; Lubatti, H.J.; Moriyasu, K.; Wolin, E.

    1989-01-01

    In an experiment (E546) to study interactions of left-angle E right-angle=100 GeV and left-angle Q 2 right-angle=17 GeV 2 neutrinos in the Fermilab 15-foot bubble chamber, we have looked for a left-right asymmetry in the azimuthal angle φ of individual hadrons about the direction of the lepton momentum transfer (q vector). Significant asymmetry is found for forward positive hadrons; for x F >0.10, we find left-angle cosφ right-angle=-0.029±0.008, where x F is the Feynman x variable. Negative hadrons with x F >0.10 show no asymmetry, left-angle cosφ right-angle=0.004±0.011. A model which includes parton intrinsic transverse momentum k t reproduces the asymmetry of combined positive and negative hadrons with x F >0.10, left-angle cosφ right-angle=-0.018±0.0065, if left-angle k t 2 right-angle=0.065±0.024 GeV 2 /c 2 . But the model predicts almost equal asymmetries for positive and negative hadrons. The model also agrees poorly with the observed dependence on the kinematic variables x and Q 2 if the k t distribution is assumed to be independent of kinematic variables

  6. Hemispheric asymmetry and theory of mind: is there an association?

    Science.gov (United States)

    Herzig, Daniela A; Sullivan, Sarah; Evans, Jonathan; Corcoran, Rhiannon; Mohr, Christine

    2012-01-01

    In autism and schizophrenia attenuated/atypical functional hemispheric asymmetry and theory of mind impairments have been reported, suggesting common underlying neuroscientific correlates. We here investigated whether impaired theory of mind performance is associated with attenuated/atypical hemispheric asymmetry. An association may explain the co-occurrence of both dysfunctions in psychiatric populations. Healthy participants (n=129) performed a left hemisphere (lateralised lexical decision task) and right hemisphere (lateralised face decision task) dominant task as well as a visual cartoon task to assess theory of mind performance. Linear regression analyses revealed inconsistent associations between theory of mind performance and functional hemisphere asymmetry: enhanced theory of mind performance was only associated with (1) faster right hemisphere language processing, and (2) reduced right hemisphere dominance for face processing (men only). The majority of non-significant findings suggest that theory of mind and functional hemispheric asymmetry are unrelated. Instead of "overinterpreting" the two significant results, discrepancies in the previous literature relating to the problem of the theory of mind concept, the variety of tasks, and the lack of normative data are discussed. We also suggest how future studies could explore a possible link between hemispheric asymmetry and theory of mind.

  7. [Perception of asymmetry smile: Attempt to evaluation through Photoshop].

    Science.gov (United States)

    Diakite, C; Diep, D; Labbe, D

    2016-04-01

    In the labial palliative surgery of facial paralysis, it can persist asymmetry smile. Evaluate the impact of an augmentation or reduction of the commissural course on the perception of a smile anomaly, and determine from which asymmetry threshold, the smile is estimated unsightly. We took a picture of two people with a smile not forced; including one with a "cuspid smile", and the another one with a "Mona Lisa" smile. The pictures obtained were modified by the Photoshop software, to simulate an asymmetry labial smile. The changes were related to the move of the left labial commissure, the left nasolabial furrow, and the left cheek using under-correction and overcorrection, every 4 mm. Three pictures with under-correction and four pictures with over-correction were obtained. These smiles were shown to three groups of five people, which included doctors in smile specialties, doctors in other specialties, and non-doctors. Participants were then asked to indicate on which of the pictures, the smile seemed abnormal. Between -8 mm under-correction, and +8 mm over-correction, the asymmetry of the commissural course does not hinder the perception of smile. In the labial palliative surgery of facial paralysis, in the case of persistent asymmetry, there is a tolerance in the perception of "normality" of smile concerning the amplitude of the commissural course going up to 8 mm of asymmetric with under-correction or over-correction. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  8. STUDY OF FACIAL ASYMMETRY IN PATIENTS WITH DENTOMAXILLARY ANOMALIES

    Directory of Open Access Journals (Sweden)

    Daniela Anistoroaei

    2011-09-01

    Full Text Available The study aimed at establishing the prevalence index of facial asymmetry by extraoral clinical examination of orthodontic patients. The group of study included 384 subjects, selected from the patients who required a specialized orthodontic treatment. Facial asymmetry was evaluated by the parallelism of the horizontal planes and deviation of the menton and nasal pyramid. The age, sex and ecological environment from which one came, the type of dentition and of dento-maxillary anomaly were registered for each patient in part. In the experimental group, facial asymmetry was present in 4.7% of patients, menton deviation in 5.7%, and nasal pyramid deviation - in 3.4%. Significant associations were established between facial asymmetry and the type of dento-maxillary anomaly, classes of age and type of dentition. The results obtained indicate that the prevalence of facial asymmetries in orthodontic patients is especially important for the clinician, as the deviations should be established prior to the initiation of any orthodontic – possibly surgical - treatment.

  9. Frontal EEG Asymmetry of Mood: A Mini-Review

    Directory of Open Access Journals (Sweden)

    Massimiliano Palmiero

    2017-11-01

    Full Text Available The present mini-review was aimed at exploring the frontal EEG asymmetry of mood. With respect to emotion, interpreted as a discrete affective process, mood is more controllable, more nebulous, and more related to mind/cognition; in addition, causes are less well-defined than those eliciting emotion. Therefore, firstly, the rational for the distinction between emotion and mood was provided. Then, the main frontal EEG asymmetry models were presented, such as the motivational approach/withdrawal, valence/arousal, capability, and inhibition asymmetric models. Afterward, the frontal EEG asymmetry of mood was investigated following three research lines, that is considering studies involving different mood induction procedures, dispositional mood (positive and negative affect, and mood alterations in both healthy and clinical populations. In general, results were found to be contradictory, no model is unequivocally supported regardless the research line considered. Different methodological issues were raised, such as: the composition of samples used across studies, in particular, gender and age were found to be critical variables that should be better addressed in future studies; the importance of third variables that might mediate the relationship between frontal EEG asymmetries and mood, for example bodily states and hormonal responses; the role of cognition, namely the interplay between mood and executive functions. In light of these issues, future research directions were proposed. Amongst others, the need to explore the neural connectivity that underpins EEG asymmetries, and the need to include both positive and negative mood conditions in the experimental designs have been highlighted.

  10. Infant Positioning, Baby Gear Use, and Cranial Asymmetry.

    Science.gov (United States)

    Zachry, Anne H; Nolan, Vikki G; Hand, Sarah B; Klemm, Susan A

    2017-12-01

    Objectives This study aimed to identify predictors of cranial asymmetry. We hypothesize that among infants diagnosed with cranial asymmetry in the sampled region, there is an association between exposure to more time in baby gear and less awake time in prone and side-lying than in infants who do not present with this condition. Methods The study employed a cross sectional survey of caregivers of typically developing infants and infants diagnosed with cranial asymmetry. Results A mutivariable model reveals that caregivers of children who are diagnosed with cranial asymmetry report their children spending significantly less time in prone play than those children without a diagnosis of cranial asymmetry. Side-lying and time spent in baby gear did not attain statistical significance. Conclusions for Practice Occupational therapists, physical therapists, pediatricians, nurses and other health care professionals must provide parents with early education about the importance of varying positions and prone play in infancy and address fears and concerns that may serve as barriers to providing prone playtime.

  11. Negative-strand RNA viruses: The plant-infecting counterparts

    NARCIS (Netherlands)

    Kormelink, R.J.M.; Garcia, M.L.; Goodin, M.; Sasaya, T.; Haenni, A.L.

    2011-01-01

    While a large number of negative-strand (-)RNA viruses infect animals and humans, a relative small number have plants as their primary host. Some of these have been classified within families together with animal/human infecting viruses due to similarities in particle morphology and genome

  12. Double-Strand DNA Break Repair in Mycobacteria.

    Science.gov (United States)

    Glickman, Michael S

    2014-10-01

    Discontinuity of both strands of the chromosome is a lethal event in all living organisms because it compromises chromosome replication. As such, a diversity of DNA repair systems has evolved to repair double-strand DNA breaks (DSBs). In part, this diversity of DSB repair systems has evolved to repair breaks that arise in diverse physiologic circumstances or sequence contexts, including cellular states of nonreplication or breaks that arise between repeats. Mycobacteria elaborate a set of three genetically distinct DNA repair pathways: homologous recombination, nonhomologous end joining, and single-strand annealing. As such, mycobacterial DSB repair diverges substantially from the standard model of prokaryotic DSB repair and represents an attractive new model system. In addition, the presence in mycobacteria of a DSB repair system that can repair DSBs in nonreplicating cells (nonhomologous end joining) or when DSBs arise between repeats (single-strand annealing) has clear potential relevance to Mycobacterium tuberculosis pathogenesis, although the exact role of these systems in M. tuberculosis pathogenesis is still being elucidated. In this article we will review the genetics of mycobacterial DSB repair systems, focusing on recent insights.

  13. Short Communication A near mass stranding of cetaceans in St ...

    African Journals Online (AJOL)

    A group of 70 false killer whales Pseudorca crassidens and 124 bottlenose dolphins Tursiops sp., and a separate group of 13 Risso's dolphins Grampus griseus, assembled close inshore off a known mass-stranding site in St Helena Bay, South Africa, in October 2003. However, only a single Risso's dolphin attempted to ...

  14. Repair of double-strand breaks in Micrococcus radiodurans

    International Nuclear Information System (INIS)

    Burrell, A.D.; Dean, C.J.

    1975-01-01

    Micrococcus radiodurans has been shown to sustain double-strand breaks in its DNA after exposure to x-radiation. Following sublethal doses of x-rays (200 krad in oxygen or less), the cells were able to repair these breaks, and an intermediate fast-sedimenting DNA component seemed to be involved in the repair process

  15. RRP Nb3Sn strand studies for LARP

    International Nuclear Information System (INIS)

    Barzi, Emanuela; Bossert, Rodger; Caspi, Shlomo; Dietderich, Daniel R.; Ferracin, Paolo; Ghosh, Arup; Turrioni, Daniele

    2006-01-01

    The Nb 3 Sn strand chosen for the next step in the magnet R and D of the U.S. LHC Accelerator Research Program is the 54/61 sub-element Restacked Rod Process by Oxford Instruments, Superconducting Technology. To ensure that the 0.7 mm RRP strands to be used in the upcoming LARP magnets are suitable, extensive studies were performed. Measurements included the critical current, e , using the voltage-current (V-I) method, the stability current, I S , as the minimal quench current obtained with the voltage-field (V-H) method, and RRR. Magnetization was measured at low and high fields to determine the effective filament size and to detect flux jumps. Effects of heat treatment temperature and durations on I e and I S were also studied. Using strand billet qualification and tests of strands extracted from cables, the short sample limits of magnet performance were obtained. The details and the results of this investigation are herein described

  16. RRP Nb3Sn Strand Studies for LARP

    International Nuclear Information System (INIS)

    Barzi, Emanuela; Bossert, Rodger; Caspi, Shlomo; Dietderich, Daniel R.; Ferracin, Paolo; Ghosh, Arup; Turrioni, Daniele

    2007-01-01

    The Nb 3 Sn strand chosen for the next step in the magnet R and D of the U.S. LHC Accelerator Research Program is the 54/61 sub-element Restacked Rod Process by Oxford Instruments, Superconducting Technology. To ensure that the 0.7 mm RRP strands to be used in the upcoming LARP magnets are suitable, extensive studies were performed. Measurements included the critical current, I c , using the voltage-current (V-I) method, the stability current, I S , as the minimal quench current obtained with the voltage-field (V-H) method, and RRR. Magnetization was measured at low and high fields to determine the effective filament size and to detect flux jumps. Effects of heat treatment temperature and durations on I c and I S were also studied. Using strand billet qualification and tests of strands extracted from cables, the short sample limits of magnet performance were obtained. The details and the results of this investigation are herein described

  17. Strategies underlying RNA silencing suppression by negative strand RNA viruses

    NARCIS (Netherlands)

    Hemmes, J.C.

    2007-01-01

    The research described in this thesis focused on the strategies of negative strand RNA viruses to counteract antiviral RNA silencing. In plants and insects, RNA silencing has been shown to act as a sequence specific antiviral defence mechanism that is characterised by the processing of double

  18. Primary resistance to integrase strand-transfer inhibitors in Europe.

    NARCIS (Netherlands)

    M. Casadellá; P.M. van Ham (Petra); M. Noguera-Julian; A. van Kessel; C. Pou; L.M. Hofstra (Marije); G.A. Metcalf (Ginger A.); F. Garcia; D. Struck (Daniel); I. Alexiev (Ivailo); A.M. Bakken Kran; A.I.M. Hoepelman; L.G. Kostrikis (Leondios); S. Somogyi; K. Liitsola (Kirsi); M. Linka (Marek); C. Nielsen; D. Otelea (Dan); D. Paraskevis (Dimitrios); M. Poljak (Mario); E. Puchhammer-Stöckl (Elisabeth); D. Stanekova (Danica); M. Stanojevic (Maja); K. Van Laethem (Kristel); S. Zidovec Lepej (Snjezana); B. Clotet; C.A.B. Boucher (Charles); R. Paredes (Roger); A.M.J. Wensing (Annemarie)

    2015-01-01

    markdownabstractThe objective of this study was to define the natural genotypic variation of the HIV-1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer inhibitor (InSTI) resistance. This was a multicentre, cross-sectional study within the European SPREAD

  19. Primary resistance to integrase strand-transfer inhibitors in Europe

    NARCIS (Netherlands)

    Casadella, M.; van Ham, P. M.; Noguera-Julian, M.; van Kessel, A.; Pou, C.; Hofstra, L. M.; Santos, J. R.; Garcia, F.; Struck, D.; Alexiev, I.; Kran, A. M. Bakken; Hoepelman, A. I.; Kostrikis, L. G.; Somogyi, S.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paraskevis, D.; Poljak, M.; Puchhammer-Stoeckl, E.; Stanekova, D.; Stanojevic, M.; Van Laethem, K.; Lepej, S. Zidovec; Clotet, B.; Boucher, C. A. B.; Paredes, R.; Wensing, A. M. J.; Schuurman, R

    2015-01-01

    Objectives: The objective of this study was to define the natural genotypic variation of the HIV-1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer inhibitor (InSTI) resistance. Methods: This was a multicentre, cross-sectional study within the European

  20. DNA double-strand breaks & poptosis in the testis

    NARCIS (Netherlands)

    Hamer, Geert

    2003-01-01

    During spermatogenesis, DNA damage is a naturally occurring event. At a certain stage, during the first meiotic prophase, DNA breaks are endogenously induced and even required for meiotic recombination. We studied these DNA breaks but also used ionizing radiation (IR) to induce DNA double-strand

  1. Cetaceans stranded in the Netherlands from 1998 to 2007

    NARCIS (Netherlands)

    Camphuysen, C.J.; Smeenk, C.; Addink, M.; Grouw, van H.; Jansen, O.E.

    2008-01-01

    Between 1998 and 2007, 2063 cetaceans were found stranded in the Netherlands, representing at least 14 species. Two species, humpback whale (Megaptera novaeangliae) and Blainville's beaked whale (Mesoplodon densirostris), are additions to the Dutch list. Apart from the first humpback whales,

  2. DNA strand exchange catalyzed by molecular crowding in PEG solutions

    KAUST Repository

    Feng, Bobo; Frykholm, Karolin; Nordé n, Bengt; Westerlund, Fredrik

    2010-01-01

    DNA strand exchange is catalyzed by molecular crowding and hydrophobic interactions in concentrated aqueous solutions of polyethylene glycol, a discovery of relevance for understanding the function of recombination enzymes and with potential applications to DNA nanotechnology. © 2010 The Royal Society of Chemistry.

  3. 75 FR 8113 - Prestressed Concrete Steel Wire Strand From China

    Science.gov (United States)

    2010-02-23

    ... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-464 and 731-TA-1160 (Final)] Prestressed Concrete Steel Wire Strand From China AGENCY: United States International Trade Commission. ACTION: Revised schedule for the subject investigations. DATES: Effective Date: February 16, 2010. FOR FURTHER INFORMATION...

  4. 75 FR 4104 - Prestressed Concrete Steel Wire Strand From China

    Science.gov (United States)

    2010-01-26

    ... retarded, by reason of subsidized and less-than-fair-value imports from China of prestressed concrete steel... in prestressed concrete (both pre-tensioned and post- tensioned) applications. The product definition..., producers, or exporters in China of prestressed concrete steel wire strand, and that such products are being...

  5. Frequency of dentofacial asymmetries: a cross-sectional study on orthodontic patients.

    Science.gov (United States)

    Bhateja, Nita Kumari; Fida, Mubassar; Shaikh, Attiya

    2014-01-01

    Correction of orthodontic asymmetries is crucial to achieve functional occlusion, aesthetics and stability of post orthodontic treatment results. To date valid frequency data of dentofacial asymmetries in Pakistani orthodontic patients do not exist to document orthodontic treatment need. The objectives of this study were to determine frequency of dento-facial asymmetries, severity of dental asymmetries and to determine difference in frequency of dentofacial asymmetries in mixed and permanent dentition. The sample of this cross-sectional study comprised of 280 patients (177 females and 103 males) with no history of previous orthodontic treatment having no craniofacial anomalies. Dento-facial asymmetries were assessed from pre-treatment records of patients. Descriptive statistics were used to determine frequency of dentofacial asymmetries and severity of dental asymmetries. Chi-square test was used to determine difference in frequency of dentofacial asymmetries in mixed and permanent dentition. Seventy eight percent (219) of patients had noncoincident midlines, 67.5% (189) had mandibular midline asymmetry, 43.2% (122) had molar asymmetry, 15.7% (44) had mandibular arch asymmetry, 14.3% (40) had maxillary midline asymmetry, 13.6% (38) had maxillary arch asymmetry, 6.1% (17) had nose deviation, and 12.1% (34) had facial asymmetry and chin deviation. In most patients dental midlines were deviated from one another and from facial midline by ¼ lower incisor widths, while molar asymmetry was found in most patients by ¼ cusp width. Mandibular arch asymmetry was more frequent in permanent than mixed dentition (p = 0.054). Non-coincident dental midline is most commonly seen. Nose deviation is least commonly observed. Mandibular arch asymmetry is more frequent in permanent than mixed dentition.

  6. RNA STRAND: The RNA Secondary Structure and Statistical Analysis Database

    Directory of Open Access Journals (Sweden)

    Andronescu Mirela

    2008-08-01

    Full Text Available Abstract Background The ability to access, search and analyse secondary structures of a large set of known RNA molecules is very important for deriving improved RNA energy models, for evaluating computational predictions of RNA secondary structures and for a better understanding of RNA folding. Currently there is no database that can easily provide these capabilities for almost all RNA molecules with known secondary structures. Results In this paper we describe RNA STRAND – the RNA secondary STRucture and statistical ANalysis Database, a curated database containing known secondary structures of any type and organism. Our new database provides a wide collection of known RNA secondary structures drawn from public databases, searchable and downloadable in a common format. Comprehensive statistical information on the secondary structures in our database is provided using the RNA Secondary Structure Analyser, a new tool we have developed to analyse RNA secondary structures. The information thus obtained is valuable for understanding to which extent and with which probability certain structural motifs can appear. We outline several ways in which the data provided in RNA STRAND can facilitate research on RNA structure, including the improvement of RNA energy models and evaluation of secondary structure prediction programs. In order to keep up-to-date with new RNA secondary structure experiments, we offer the necessary tools to add solved RNA secondary structures to our database and invite researchers to contribute to RNA STRAND. Conclusion RNA STRAND is a carefully assembled database of trusted RNA secondary structures, with easy on-line tools for searching, analyzing and downloading user selected entries, and is publicly available at http://www.rnasoft.ca/strand.

  7. Characterization of a parallel-stranded DNA hairpin

    International Nuclear Information System (INIS)

    Germann, M.W.; Vogel, H.J.; Pon, R.T.; van de Sande, J.H.

    1989-01-01

    Recently, the authors have shown that synthetic DNA containing homooligomeric A-T base pairs can form a parallel-stranded intramolecular hairpin structure. In the present study, they have employed NMR and optical spectroscopy to investigate the structure of the parallel-stranded (PS) DNA hairpin 3'-d(T) 8 C 4 (A) 8 -3' and the related antiparallel (APS) hair 5'-d(T) 8 C 4 (A) 8 -3'. The parallel orientation of the strands in the PS oligonucleotide is achieved by introducing a 5'-5' phosphodiester linkage in the hairpin loop. Ultraviolet spectroscopic and fluorescence data of drug binding are consistent with the formation of PS and APS structures, respectively, in these two hairpins. Vacuum circular dichroism measurements in combination with theoretical CD calculations indicate that the PS structure forms a right-handed helix. 31 P NMR measurements indicate that the conformation of the phosphodiester backbone of the PS structure is not drastically different from that of the APS control. The presence of slowly exchanging imino protons at 14 ppm and the observation of nuclear Overhauser enhancement between imino protons and the AH-2 protons demonstrate that similar base pairing and base stacking between T and A residues occur in both hairpins. On the basis of NOESY measurements, they find that the orientation of the bases is in the anti region and that the sugar puckering is in the 2'-endo range. The results indicate a B-like conformation for each of the strands in the stem part of the PS hairpin and reverse Watson-Crick base pairing between the T and A residues. These data are consistent with a previously calculated structure for parallel-stranded DNA

  8. Sterile neutrinos, lepton asymmetries, primordial elements: How much of each?

    International Nuclear Information System (INIS)

    Chu Yizen; Cirelli, Marco

    2006-01-01

    We investigate quantitatively the extent to which having a primordial leptonic asymmetry (n ν ≠n ν ) relaxes the bounds on light sterile neutrinos imposed by BBN and LSS. We adopt a few assumptions that allow us to solve the neutrino evolution equations over a broad range of mixing parameters and asymmetries. For the general cases of sterile mixing with the electron or muon neutrino, we identify the regions that can be reopened. For the particular case of a LSND-like sterile neutrino, soon to be rejected or confirmed by MiniBooNE, we find that an asymmetry of the order of 10 -4 is needed to lift the conflicts with cosmology

  9. Visual Representation Determines Search Difficulty: Explaining Visual Search Asymmetries

    Directory of Open Access Journals (Sweden)

    Neil eBruce

    2011-07-01

    Full Text Available In visual search experiments there exist a variety of experimental paradigms in which a symmetric set of experimental conditions yields asymmetric corresponding task performance. There are a variety of examples of this that currently lack a satisfactory explanation. In this paper, we demonstrate that distinct classes of asymmetries may be explained by virtue of a few simple conditions that are consistent with current thinking surrounding computational modeling of visual search and coding in the primate brain. This includes a detailed look at the role that stimulus familiarity plays in the determination of search performance. Overall, we demonstrate that all of these asymmetries have a common origin, namely, they are a consequence of the encoding that appears in the visual cortex. The analysis associated with these cases yields insight into the problem of visual search in general and predictions of novel search asymmetries.

  10. Tension-compression asymmetry modelling: strategies for anisotropy parameters identification.

    Directory of Open Access Journals (Sweden)

    Barros Pedro

    2016-01-01

    Full Text Available This work presents details concerning the strategies and algorithms adopted in the fully implicit FE solver DD3IMP to model the orthotropic behavior of metallic sheets and the procedure for anisotropy parameters identification. The work is focused on the yield criterion developed by Cazacu, Plunkett and Barlat, 2006 [1], which accounts for both tension–compression asymmetry and orthotropic plastic behavior. The anisotropy parameters for a 2090-T3 aluminum alloy are identified accounting, or not, for the tension-compression asymmetry. The numerical simulation of a cup drawing is performed for this material, highlighting the importance of considering tension-compression asymmetry in the prediction of the earing profile, for materials with cubic structure, even if this phenomenon is relatively small.

  11. Biometric identification based on novel frequency domain facial asymmetry measures

    Science.gov (United States)

    Mitra, Sinjini; Savvides, Marios; Vijaya Kumar, B. V. K.

    2005-03-01

    In the modern world, the ever-growing need to ensure a system's security has spurred the growth of the newly emerging technology of biometric identification. The present paper introduces a novel set of facial biometrics based on quantified facial asymmetry measures in the frequency domain. In particular, we show that these biometrics work well for face images showing expression variations and have the potential to do so in presence of illumination variations as well. A comparison of the recognition rates with those obtained from spatial domain asymmetry measures based on raw intensity values suggests that the frequency domain representation is more robust to intra-personal distortions and is a novel approach for performing biometric identification. In addition, some feature analysis based on statistical methods comparing the asymmetry measures across different individuals and across different expressions is presented.

  12. Transverse spin asymmetry at the A4 experiment

    International Nuclear Information System (INIS)

    Baunack, Sebastian

    2005-01-01

    The A4 collaboration at the MAMI accelerator has measured the transverse spin asymmetry in the cross section of elastic scattering of transversely polarized electrons off unpolarized protons. An azimuthal dependence of the asymmetry has been observed, the amplitudes have been determined as A bot (Q 2 =0.106 (GeV/c) 2 )=( -8.59 ±0.89 stat ±0.75 syst ).10 -6 and A bot (Q 2 =0.230 (GeV/c) 2 )=(-8.52±2.31 stat ±0.87 syst ).10 -6 . A bot arises from the imaginary part of the 2γ-exchange amplitude. Our experimentally determined values of A bot show that in the intermediate hadronic state not only the ground state of the proton, but also excited states contribute to the asymmetry. (orig.)

  13. Bessel-Weighted Asymmetries in Semi Inclusive Deep Inelastic Scattering

    International Nuclear Information System (INIS)

    Boer, D.; Gamberg, L.; Musch, B.U.; Prokudin, A.

    2011-01-01

    The concept of weighted asymmetries is revisited for semi-inclusive deep inelastic scattering. We consider the cross section in Fourier space, conjugate to the outgoing hadron's transverse momentum, where convolutions of transverse momentum dependent parton distribution functions and fragmentation functions become simple products. Individual asymmetric terms in the cross section can be projected out by means of a generalized set of weights involving Bessel functions. Advantages of employing these Bessel weights are that they suppress (divergent) contributions from high transverse momentum and that soft factors cancel in (Bessel-) weighted asymmetries. Also, the resulting compact expressions immediately connect to previous work on evolution equations for transverse momentum dependent parton distribution and fragmentation functions and to quantities accessible in lattice QCD. Bessel weighted asymmetries are thus model independent observables that augment the description and our understanding of correlations of spin and momentum in nucleon structure.

  14. MANDIBULAR ASYMMETRY CHARACTERIZATION USING GENERALIZED TENSOR-BASED MORPHOMETRY.

    Science.gov (United States)

    Paniagua, Beatriz; Alhadidi, Abeer; Cevidanes, Lucia; Styner, Martin; Oguz, Ipek

    2011-12-31

    Quantitative assessment of facial asymmetry is crucial for successful planning of corrective surgery. We propose a tensor-based morphometry (TBM) framework to locate and quantify asymmetry using 3D CBCT images. To this end, we compute a rigid transformation between the mandible segmentation and its mirror image, which yields global rotation and translation with respect to the cranial base to guide the surgery's first stage. Next, we nonrigidly register the rigidly aligned images and use TBM methods to locally analyze the deformation field. This yields data on the location, amount and direction of "growth" (or "shrinkage") between the left and right sides. We visualize this data in a volumetric manner and via scalar and vector maps on the mandibular surface to provide the surgeon with optimal understanding of the patient's anatomy. We illustrate the feasibility and strength of our technique on 3 representative patients with a wide range of facial asymmetries.

  15. Baryon asymmetry, dark matter and local baryon number

    International Nuclear Information System (INIS)

    Fileviez Pérez, Pavel; Patel, Hiren H.

    2014-01-01

    We propose a new mechanism to understand the relation between baryon and dark matter asymmetries in the universe in theories where the baryon number is a local symmetry. In these scenarios the B−L asymmetry generated through a mechanism such as leptogenesis is transferred to the dark matter and baryonic sectors through sphalerons processes which conserve total baryon number. We show that it is possible to have a consistent relation between the dark matter relic density and the baryon asymmetry in the universe even if the baryon number is broken at the low scale through the Higgs mechanism. We also discuss the case where one uses the Stueckelberg mechanism to understand the conservation of baryon number in nature.

  16. The beta decay asymmetry parameter of 35Ar

    International Nuclear Information System (INIS)

    Garnett, J.D.

    1987-11-01

    The beta decay asymmetry parameter for 35 Ar = 35 Cl + e + + nu/sub e/ has been remeasured in order to resolve a long standing puzzle. Previous asymmetry measurements, when combined with the comparative half-life, yield a value for the vector coupling constant, G/sub v/, that is in serious disagreement with the accepted value. We produced polarized 35 Ar by a (p,n) reaction on 35 Cl using the polarized proton beam provided by Lawrence Berkeley Laboratory's 88-Inch Cyclotron. The polarization of the 35 Ar was determined by measuring the asymmetry of the positrons produced in 35 Ar decay to the first excited state in 35 Cl (branching ratio = 1.3%) in coincidence with a 1219.4 keV gamma ray. Our result, A 0 = 0.49 +- 0.10, combined with the comparative half-life yields a value for G/sub v/ in agreement with the accepted value

  17. PERANAN KONSERVATISME PADA INFORMATION ASYMMETRY: SUATU TINJAUAN TEORETIS

    Directory of Open Access Journals (Sweden)

    I G.A.N. BUDIASIH

    2011-07-01

    Full Text Available Conservatism is one of mechanisms of corporate governance that could reduce managers’ capability to manipulate and overstate financial report, especially financial performance, so cash flow and company’s value could be increased. Conservatism is also important in decreasing agency cost and increasing the quality of financial information to increase company’s value and the share price. Financial statement employing principle of conservatism could reduce management chance to manipulate financial report and decrease deadweight loss as an agency cost emerged due to information asymmetry. Thus it can be said that conservative financial statement could reduce information asymmetry. Information asymmetry can be handled by forcing management to fully disclose the company’s condition on the financial statement. Another way is to monitor management conduct by employing independent auditor.

  18. Investors’ risk attitudes and stock price fluctuation asymmetry

    Science.gov (United States)

    Zhang, Yu; Li, Honggang

    2011-05-01

    Price rise/fall asymmetry, which indicates enduring but modest rises and sudden short-term falls, is a ubiquitous phenomenon in stock markets throughout the world. Instead of the widely used time series method, we adopt inverse statistics from turbulence to analyze this asymmetry. To explore its underlying mechanism, we build a multi-agent model with two kinds of investors, which are specifically referred to as fundamentalists and chartists. Inspired by Kahneman and Tversky’s claim regarding peoples’ asymmetric psychological responses to the equivalent levels of gains and losses, we assume that investors take different risk attitudes to gains and losses and adopt different trading strategies. The simulation results of the model developed herein are consistent with empirical work, which may support our conjecture that investors’ asymmetric risk attitudes might be one origin of rise/fall asymmetry.

  19. Take your seats: Leftward asymmetry in classroom seating choice

    Directory of Open Access Journals (Sweden)

    Victoria Lynn Harms

    2015-08-01

    Full Text Available Despite an overall body symmetry, human behaviour is full of examples of asymmetry, from writing or gesturing to kissing and cradling. Prior research has revealed that theatre patrons show a bias towards sitting on the right side of a movie theatre. Two competing theories have attempted to explain this seating asymmetry: one posits that expectation of processing demand drives the bias; the other posits that basic motor asymmetries drive the bias. To test these theories we assessed the real-world classroom seating choices of university students using photographs. A bias for students to choose seats on the left side of the classroom was observed, in contrast to the right side bias observed in theatre seating studies. These results provide evidence in support of a processing-expectation bias.

  20. Right-frontal cortical asymmetry predicts increased proneness to nostalgia.

    Science.gov (United States)

    Tullett, Alexa M; Wildschut, Tim; Sedikides, Constantine; Inzlicht, Michael

    2015-08-01

    Nostalgia is often triggered by feelings-such as sadness, loneliness, or meaninglessness-that are typically associated with withdrawal motivation. Here, we examined whether a trait tendency to experience withdrawal motivation is associated with nostalgia proneness. Past work indicates that baseline right-frontal cortical asymmetry is a neural correlate of withdrawal-related motivation. We therefore hypothesized that higher baseline levels of right-frontal asymmetry would predict increased proneness to nostalgia. We assessed participants' baseline levels of frontal cortical activity using EEG. Results supported the hypothesis and demonstrated that the association between relative right-frontal asymmetry and increased nostalgia remained significant when controlling for the Big Five personality traits. Overall, these findings indicate that individuals with a stronger dispositional tendency to experience withdrawal-related motivation are more prone to nostalgia. © 2015 Society for Psychophysiological Research.

  1. Reducing the asymmetry in coupled cavity of linear accelerator

    International Nuclear Information System (INIS)

    Wei Xianlin; Wu Congfeng

    2013-01-01

    Background: With the development of high energy physics, high performance of electron linear accelerator is required for large collider, FEL and high brightness synchrotron radiation light source. Structure asymmetry of single coupler destroys the symmetry of field distribution in coupled cavity, which reduces the quality of beam. Purpose: Optimize the asymmetry of field distribution in coupled cavity and improve the quality of beam. Methods: The simulation designs are made for single offset coupler, double symmetry coupler and the new coupler loaded by dielectric rods at X band by using CST microwave studio code. Results: The results show that the distribution of field in coupled cavity is better and all particles almost locate at the center of beam hole after beam passing through the coupler loaded by dielectric rods. The energy spread has also been significantly improved. Conclusions: The coupler loaded by dielectric rods can optimize the asymmetry of field distribution in coupled cavity and improve the quality of beam. (authors)

  2. Proton GE/GM from beam-target asymmetry

    International Nuclear Information System (INIS)

    Mark Jones; Aram Aghalaryan; Abdellah Ahmidouch; Razmik Asaturyan; Frederic Bloch; Werner Boeglin; Peter Bosted; Cedric Carasco; Roger Carlini; Jinseok Cha; Jian-Ping Chen; Michael Christy; Leon Cole; Luminita Coman; Donald Crabb; Samuel Danagoulian; Donal Day; James Dunne; Mostafa Elaasar; Rolf Ent; Howard Fenker; Emil Frlez; David Gaskell; Liping Gan; Javier Gomez; Bitao Hu; Juerg Jourdan; Christopher Keith; Cynthia Keppel; Mahbubul Khandaker; Andreas Klein; Laird Kramer; Yongguang Liang; Jechiel Lichtenstadt; Richard Lindgren; David Mack; Paul McKee; Dustin McNulty; David Meekins; Hamlet Mkrtchyan; Rakhsha Nasseripour; Maria-Ioana Niculescu; Kristoff Normand; Blaine Norum; Dinko Pocanic; Yelena Prok; Brian Raue; Joerg Reinhold; Julie Roche; Daniela Rohe; Oscar Rondon-Aramayo; Nikolai Savvinov; Bradley Sawatzky; Mikell Seely; Ingo Sick; Karl Slifer; C. Smith; Gregory Smith; S. Stepanyan; Liguang Tang; Shigeyuki Tajima; Giuseppe Testa; William Vulcan; Kebin Wang; Glen Warren; Frank Wesselmann; Stephen Wood; Chen Yan; Lulin Yuan; Junho Yun; Markus Zeier; Hong Guo Zhu

    2006-01-01

    The ratio of the proton's electric to magnetic form factor, G E /G M , can be extracted in elastic electron-proton scattering by measuring either cross sections, beam-target asymmetry or recoil polarization. Separate determinations of G E /G M by cross sections and recoil polarization observables disagree for Q 2 > 1 (GeV/c) 2 . Measurement by a third technique might uncover an unknown systematic error in either of the previous measurements. The beam-target asymmetry has been measured for elastic electron-proton scattering at Q 2 = 1.51 (GeV/c) 2 for target spin orientation aligned perpendicular to the beam momentum direction. This is the largest Q 2 at which G E /G M has been determined by a beam-target asymmetry experiment. The result, μG E /G M = 0.884 +/- 0.027 +/- 0.029, is compared to previous world data

  3. Transverse target spin asymmetries in exclusive $\\rho^0$ muoproduction

    CERN Document Server

    Adolph, C; Alexakhin, V Yu; Alexandrov, Yu; Alexeev, G D; Amoroso, A; Andrieux, V; Austregesilo, A; Badelek, B; Balestra, F; Barth, J; Baum, G; Bedfer, Y; Berlin, A; Bernhard, J; Bertini, R; Bicker, K; Bieling, J; Birsa, R; Bisplinghoff, J; Boer, M; Bordalo, P; Bradamante, F; Braun, C; Bravar, A; Bressan, A; Büchele, M; Burtin, E; Capozza, L; Chiosso, M; Chung, S U; Cicuttin, A; Crespo, M L; Dalla Torre, S; Dasgupta, S S; Dasgupta, S; Denisov, O Yu; Donskov, S V; Doshita, N; Duic, V; Dünnweber, W; Dziewiecki, M; Efremov, A; Elia, C; Eversheim, P D; Eyrich, W; Faessler, M; Ferrero, A; Filin, A; Finger, M; Finger, M jr; Fischer, H; Franco, C; du Fresne von Hohenesche, N; Friedrich, J M; Frolov, V; Garfagnini, R; Gautheron, F; Gavrichtchouk, O P; Gerassimov, S; Geyer, R; Giorgi, M; Gnesi, I; Gobbo, B; Goertz, S; Grabmüller, S; Grasso, A; Grube, B; Gushterski, R; Guskov, A; Guthörl, T; Haas, F; von Harrach, D; Hahne, D; Heinsius, F H; Herrmann, F; Hess, C; Hinterberger, F; Höppner, Ch; Horikawa, N; d'Hose, N; Huber, S; Ishimoto, S; Ivanshin, Yu; Iwata, T; Jahn, R; Jary, V; Jasinski, P; Joosten, R; Kabuss, E; Kang, D; Ketzer, B; Khaustov, G V; Khokhlov, Yu A; Kisselev, Yu; Klein, F; Klimaszewski, K; Koivuniemi, J H; Kolosov, V N; Kondo, K; Königsmann, K; Konorov, I; Konstantinov, V F; Kotzinian, A M; Kouznetsov, O; Krämer, M; Kroumchtein, Z V; Kuchinski, N; Kunne, F; Kurek, K; Kurjata, R P; Lednev, A A; Lehmann, A; Levorato, S; Lichtenstadt, J; Maggiora, A; Magnon, A; Makke, N; Mallot, G K; Marchand, C; Martin, A; Marzec, J; Matousek, J; Matsuda, H; Matsuda, T; Meshcheryakov, G; Meyer, W; Michigami, T; Mikhailov, Yu V; Miyachi, Y; Morreale, A; Nagaytsev, A; Nagel, T; Nerling, F; Neubert, S; Neyret, D; Nikolaenko, V I; Novy, J; Nowak, W D; Nunes, A.S; Olshevsky, A G; Ostrick, M; Panknin, R; Panzieri, D; Parsamyan, B; Paul, S; Pesek, M; Piragino, G; Platchkov, S; Pochodzalla, J; Polak, J; Polyakov, V A; Pretz, J; Quaresma, M; Quintans, C; Ramos, S; Reicherz, G; Rocco, E; Rodionov, V; Rondio, E; Rossiyskaya, N S; Ryabchikov, D I; Samoylenko, V D; Sandacz, A; Sapozhnikov, M G; Sarkar, S; Savin, I A; Sbrizzai, G; Schiavon, P; Schill, C; Schlüter, T; Schmidt, A; Schmidt, K; Schmitt, L; Schmïden, H; Schönning, K; Schopferer, S; Schott, M; Shevchenko, O Yu; Silva, L; Sinha, L; Sirtl, S; Slunecka, M; Sosio, S; Sozzi, F; Srnka, A; Steiger, L; Stolarski, M; Sulc, M; Sulej, R; Suzuki, H; Sznajder, P; Takekawa, S; Ter Wolbeek, J; Tessaro, S; Tessarotto, F; Thibaud, F; Uhl, S; Uman, I; Vandenbroucke, M; Virius, M; Vondra, J; Wang, L; Weisrock, T; Wilfert, M; Windmolders, R; Wislicki, W; Wollny, H; Zaremba, K; Zavertyaev, M; Zemlyanichkina, E; Zhuravlev, N; Ziembicki, M

    2014-01-01

    Exclusive production of $\\rho^0$ mesons was studied at the COMPASS experiment by scattering 160 GeV/$c$ muons off transversely polarised protons. Five single-spin and three double-spin azimuthal asymmetries were measured as a function of $Q^2$, $x_{Bj}$, or $p_{T}^{2}$. The $\\sin \\phi_S$ asymmetry is found to be $-0.019 \\pm 0.008(stat.) \\pm 0.003(syst.)$. All other asymmetries are also found to be of small magnitude and consistent with zero within experimental uncertainties. Very recent calculations using a GPD-based model agree well with the present results. The data is interpreted as evidence for the existence of chiral-odd, transverse generalized parton distributions.

  4. Load Asymmetry Observed During Orion Main Parachute Inflation

    Science.gov (United States)

    Morris, Aaron L.; Taylor, Thomas; Olson, Leah

    2011-01-01

    The Crew Exploration Vehicle Parachute Assembly System (CPAS) has flight tested the first two generations of the Orion parachute program. Three of the second generation tests instrumented the dispersion bridles of the Main parachute with a Tension Measuring System. The goal of this load measurement was to better understand load asymmetry during the inflation process of a cluster of Main parachutes. The CPAS Main parachutes exhibit inflations that are much less symmetric than current parachute literature and design guides would indicate. This paper will examine loads data gathered on three cluster tests, quantify the degree of asymmetry observed, and contrast the results with published design guides. Additionally, the measured loads data will be correlated with videos of the parachute inflation to make inferences about the shape of the parachute and the relative load asymmetry. The goal of this inquiry and test program is to open a dialogue regarding asymmetrical parachute inflation load factors.

  5. Information asymmetry, mutual funds and earnings management: Evidence from China

    Directory of Open Access Journals (Sweden)

    Yunhao Dai

    2013-09-01

    Full Text Available This paper investigates how information asymmetry and mutual fund ownership affect listed companies’ earnings management. We show that (1 reducing information asymmetry improves firms’ earnings management behavior; (2 relative to short-term mutual funds, long-term mutual funds promote earnings quality by adopting a monitoring role; and (3 by dividing firms into high/low information asymmetry groups, we find that the information environment significantly increases the effect of long-term mutual funds on firms’ earnings management. In this paper, we provide new evidence for the role that institutional investors play in a typical emerging capital market. Our results have clear policy implications: to increase earnings quality, it is essential to improve information transparency and develop long-term institutional investors.

  6. Characteristics of toroidal energy deposition asymmetries in ASDEX

    International Nuclear Information System (INIS)

    Evans, T.E.; Neuhauser, J.; Leuterer, F.; Mueller, E.R.

    1990-01-01

    Large toroidal and poloidal asymmetries with characteristics which are sensitively dependent on q a , the vertical position of the plasma, and the type of additional heating are observed in the energy flow to the ASDEX divertor target plates. The largest asymmetries and total energy depositions are observed during lower hybrid wave injection experiments with approximately 50% of the input energy going to the combined divertor targets and shields. A maximum localized energy density loading of 10 MJ/m 2 is typical under these conditions. Measurements of the asymmetries are consistent with a model in which magnetic islands and ergodicity due to intrinsic magnetic perturbations dominate the energy transpot across the primary magnetic separatrix. The results emphasize the essential role of resonant magnetic perturbations in determining the performance of tokamaks and demonstrate that non-axisymmetric effects caused by small perturbations become increasingly important in determining the transport properties as the injected power is increased. (orig.)

  7. CP asymmetries in the supersymmetric trilepton signal at the LHC

    International Nuclear Information System (INIS)

    Bornhauser, S.; Drees, M.; Dreiner, H.; Eboli, O.J.P.; Kim, J.S.; Kittel, O.

    2012-01-01

    In the CP-violating Minimal Supersymmetric Standard Model, we study the production of a neutralino-chargino pair at the LHC. For their decays into three leptons, we analyze CP asymmetries which are sensitive to the CP phases of the neutralino and chargino sector. We present analytical formulas for the entire production and decay process, and identify the CP-violating contributions in the spin correlation terms. This allows us to define the optimal CP asymmetries. We present a detailed numerical analysis of the cross sections, branching ratios, and the CP observables. For light neutralinos, charginos, and squarks, the asymmetries can reach several 10%. We estimate the discovery potential for the LHC to observe CP violation in the trilepton channel. (orig.)

  8. Harmful situations, impure people: an attribution asymmetry across moral domains.

    Science.gov (United States)

    Chakroff, Alek; Young, Liane

    2015-03-01

    People make inferences about the actions of others, assessing whether an act is best explained by person-based versus situation-based accounts. Here we examine people's explanations for norm violations in different domains: harmful acts (e.g., assault) and impure acts (e.g., incest). Across four studies, we find evidence for an attribution asymmetry: people endorse more person-based attributions for impure versus harmful acts. This attribution asymmetry is partly explained by the abnormality of impure versus harmful acts, but not by differences in the moral wrongness or the statistical frequency of these acts. Finally, this asymmetry persists even when the situational factors that lead an agent to act impurely are stipulated. These results suggest that, relative to harmful acts, impure acts are linked to person-based attributions. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Measurement of Charge Asymmetries in Charmless Hadronic B Meson Decays

    Energy Technology Data Exchange (ETDEWEB)

    Chen, S. [Purdue University, West Lafayette, Indiana 47907 (United States); Fast, J. [Purdue University, West Lafayette, Indiana 47907 (United States); Hinson, J. W. [Purdue University, West Lafayette, Indiana 47907 (United States); Lee, J. [Purdue University, West Lafayette, Indiana 47907 (United States); Menon, N. [Purdue University, West Lafayette, Indiana 47907 (United States); Miller, D. H. [Purdue University, West Lafayette, Indiana 47907 (United States); Shibata, E. I. [Purdue University, West Lafayette, Indiana 47907 (United States); Shipsey, I. P. J. [Purdue University, West Lafayette, Indiana 47907 (United States); Pavlunin, V. [Purdue University, West Lafayette, Indiana 47907 (United States); Cronin-Hennessy, D. [University of Rochester, Rochester, New York 14627 (United States)] (and others)

    2000-07-17

    We search for CP -violating charge asymmetries (A{sub CP} ) in the B meson decays to K{sup {+-}}{pi}{sup {+-}} , K{sup {+-}}{pi}{sup 0} , K{sup 0}{sub S}{pi}{sup {+-}} , K{sup {+-}}{eta}{sup '} , and {omega}{pi}{sup {+-}} . Using 9.66 million {upsilon}(4S) decays collected with the CLEO detector, the statistical precision on A{sub CP} is in the range of {+-}0.12 to {+-}0.25 depending on decay mode. While CP -violating asymmetries of up to {+-}0.5 are possible within the standard model, the measured asymmetries are consistent with zero in all five decay modes studied. (c) 2000 The American Physical Society.

  10. Four-Strand Core Suture Improves Flexor Tendon Repair Compared to Two-Strand Technique in a Rabbit Model

    Directory of Open Access Journals (Sweden)

    Alice Wichelhaus

    2016-01-01

    Full Text Available Introduction. This study was designed to investigate the influence of the amount of suture material on the formation of peritendinous adhesions of intrasynovial flexor tendon repairs. Materials and Methods. In 14 rabbits, the flexor tendons of the third and the fourth digit of the right hind leg were cut and repaired using a 2- or 4-strand core suture technique. The repaired tendons were harvested after three and eight weeks. The range of motion of the affected toes was measured and the tendons were processed histologically. The distance between the transected tendon ends, the changes in the peritendinous space, and cellular and extracellular inflammatory reaction were quantified by different staining. Results. A 4-strand core suture resulted in significantly less gap formation. The 2-strand core suture showed a tendency to less adhesion formation. Doubling of the intratendinous suture material was accompanied by an initial increase in leukocyte infiltration and showed a greater amount of formation of myofibroblasts. From the third to the eighth week after flexor tendon repair, both the cellular and the extracellular inflammation decreased significantly. Conclusion. A 4-strand core suture repair leads to a significantly better tendon healing process with less diastasis between the sutured tendon ends despite initially pronounced inflammatory response.

  11. Detection of bacteriophage phi 6 minus-strand RNA and novel mRNA isoconformers synthesized in vivo and in vitro, by strand-separating agarose gels

    International Nuclear Information System (INIS)

    Pagratis, N.; Revel, H.R.

    1990-01-01

    Two urea-free agarose gel protocols that resolve the six individual strands of bacteriophage phi 6 dsRNA were developed and used to analyze phage RNA synthesis in vivo and in vitro. Citrate gels separate strands of the large and medium chromosomes while Tris-borate-EDTA (TBE) gels resolve the medium and small dsRNA segments. Minus strands migrate faster than plus strands on citrate gels but are retarded on TBE gels. A study of electrophoretic conditions showed that pH affects strand resolution on citrate gels, and that voltage gradient, agarose concentration, and ethidium bromide significantly alter strand migration on TBE gels. Analysis of native phi 6 RNA synthesized in vivo and in vitro showed that the large and medium message RNAs comigrate with the corresponding plus strands of denatured virion dsRNA. The small messenger RNA is exceptional. Native small mRNA was detected as three isoconformers in vivo and in vitro. The isoconformers were converted by heat denaturation to a single RNA species that comigrates with the virion s+ strand. Minus strands labeled in vivo were detected only after heat denaturation. Minus strand synthesis was detected also in heat-denatured samples from in vitro phi 6 nucleocapsid RNA polymerase reactions at pH values suboptimal for transcription

  12. The relationship between skull asymmetry and CT findings

    International Nuclear Information System (INIS)

    Yamori, Yuriko; Yuge, Mariko; Kanda, Toyoko; Ashida, Hiromi; Fukase, Hiroshi

    1987-01-01

    In order to clarify the relationship between brain damage and skull asymmetry or supine head position preference, we classified CT findings of 330 cases with cerebral palsy or risk of motor disturbance into 6 groups according to skull shape. Those were severe (I, n = 37) and mild (II, n = 114) grades in the right occipital flatness, severe (III, n = 34) and mild (IV, n = 58) grades in the left occipital flatness, long skull with temporal flatness (V, n = 33) and symmetric round skull (control, n = 54). It was considered that the asymmetry of cortical atrophy in appearance was formed physicaly by skull asymmetry but that the asymmetric dilatation in appearance of lateral ventricle was related to the asymmetry of brain damage. The severity and the asymmetry of brain damage were tend to increase the grade of skull asymmetry. The incidence of cases with the right occipital flatness was 1.6 times more frequently than the left sided. The incidence of cases whose left (lateral) ventricle was larger than the right was 4.1 times more than the cases whose right ventricle was larger than the left. The cases with occipital flatness in the contralateral side of the larger lateral ventricle were found more than the cases with occipital flatness in the ipsilateral side of the larger ventricle, that is to say, the direction of supine head position preference during early infant was suspected to be the more severely disturbed side of body. These results suggest that the supine head position preference to the right in newborn babies and infants with scoliosis or cerebral palsy might be the result of transient or permanent asymmetric (left > right) brain dysfunction. (author)

  13. Ozone zonal asymmetry and planetary wave characterization during Antarctic spring

    Directory of Open Access Journals (Sweden)

    I. Ialongo

    2012-03-01

    Full Text Available A large zonal asymmetry of ozone has been observed over Antarctica during winter-spring, when the ozone hole develops. It is caused by a planetary wave-driven displacement of the polar vortex. The total ozone data by OMI (Ozone Monitoring Instrument and the ozone profiles by MLS (Microwave Limb Sounder and GOMOS (Global Ozone Monitoring by Occultation of Stars were analysed to characterize the ozone zonal asymmetry and the wave activity during Antarctic spring. Both total ozone and profile data have shown a persistent zonal asymmetry over the last years, which is usually observed from September to mid-December. The largest amplitudes of planetary waves at 65° S (the perturbations can achieve up to 50% of zonal mean values is observed in October. The wave activity is dominated by the quasi-stationary wave 1 component, while the wave 2 is mainly an eastward travelling wave. Wave numbers 1 and 2 generally explain more than the 90% of the ozone longitudinal variations. Both GOMOS and MLS ozone profile data show that ozone zonal asymmetry covers the whole stratosphere and extends up to the altitudes of 60–65 km. The wave amplitudes in ozone mixing ratio decay with altitude, with maxima (up to 50% below 30 km.

    The characterization of the ozone zonal asymmetry has become important in the climate research. The inclusion of the polar zonal asymmetry in the climate models is essential for an accurate estimation of the future temperature trends. This information might also be important for retrieval algorithms that rely on ozone a priori information.

  14. Asymmetry in electrical coupling between neurons alters multistable firing behavior

    Science.gov (United States)

    Pisarchik, A. N.; Jaimes-Reátegui, R.; García-Vellisca, M. A.

    2018-03-01

    The role of asymmetry in electrical synaptic connection between two neuronal oscillators is studied in the Hindmarsh-Rose model. We demonstrate that the asymmetry induces multistability in spiking dynamics of the coupled neuronal oscillators. The coexistence of at least three attractors, one chaotic and two periodic orbits, for certain coupling strengths is demonstrated with time series, phase portraits, bifurcation diagrams, basins of attraction of the coexisting states, Lyapunov exponents, and standard deviations of peak amplitudes and interspike intervals. The experimental results with analog electronic circuits are in good agreement with the results of numerical simulations.

  15. Sign of the day-night asymmetry for solar neutrinos

    International Nuclear Information System (INIS)

    Chiang, Cheng-Wei; Wolfenstein, Lincoln

    2001-01-01

    A qualitative understanding of the day-night asymmetry for solar neutrinos is provided. The greater night flux in ν e is seen to be a consequence of the fact that the matter effect in the Sun and that in the Earth have the same sign. It is shown in the adiabatic approximation for the Sun and constant density for the Earth that, for all values of the mixing angle θ V between 0 and π/2, the night flux of neutrinos is greater than the day flux. Only for small values of θ V where the adiabatic approximation badly fails does the sign of the day-night asymmetry reverse

  16. Think over nuclear safety. ''Information asymmetry'' and ''comminicative action''

    International Nuclear Information System (INIS)

    Suzuki, Atsuyuki

    2006-01-01

    Nuclear safety should be fully understood not only technically but also socially. In order to think over nuclear safety socially, four different concepts were recommended to refer, which were ''procedural rationality'', information asymmetry'', ''certainty effect'' and ''communicative action'' proposed by three economists and a philosopher respectively. Risk-based communication approach for nuclear safety could be effective within the higher frequency area than safety goal, but not good for the lower frequency area than safety goal. The latter could be highly subjective and more qualitative. For this area, ''safety communication'' would be highly maintained with taking account of existence of ''information asymmetry'' and need of ''communicative action''. (T.Tanaka)

  17. Spin asymmetry in resonant electron-hydrogen elastic scattering

    International Nuclear Information System (INIS)

    McCarthy, I.E.; Shang, Bo.

    1993-02-01

    Differential cross sections and asymmetries at 90 deg. and 30 deg are calculated for electron-hydrogen elastic scattering over the energies of the lowest 1 S and 3 P resonances using a nine-state coupled-channels calculation with and without continuum effects, which are represented by an equivalent-local polarization potential. The polarization potential improves agreement with experiment in general for the spin-averaged cross sections. It is suggested that continuum effects would be critically tested by asymmetry measurement at 30 deg over the 1 S resonance. 7 refs., 4 figs

  18. Posttraumatic Mandibular Asymmetry Presenting in a Young Adult

    Directory of Open Access Journals (Sweden)

    Mahnaz Sheikhi, DDS,MS

    2017-03-01

    Full Text Available One of the most common sites of injury of the facial skeleton is mandibular condyle. However, it is the least diagnosed site of trauma in the head and neck regions. A trauma to the mandible and specifically condylar zone during childhood, may lead to asymmetry or mandibular bilateral distortion, which is usually manifested in the second decade of life when the etiology is unknown to most people. This report is about an adult male complaining about facial asymmetry with an unknown source. Obvious clicking at the right side and shorter right ramus and condyle's head deviation directed us to a childhood trauma and fracture.

  19. One-spin asymmetries in pair production and Bremsstrahlung processes

    International Nuclear Information System (INIS)

    Arbuzov, A.B.; Kuraev, E.A.; Tarasov, A.V.; Merenkov, N.P.; Peresun'ko, D.Yu.

    1995-01-01

    Asymmetries in the interaction processes at high energies of circularly polarized photons or longitudinally polarized electrons with charged targets are considered. The derivations are shown in detail. The asymmetries are shown to be proportional to the degree of polarization of the initial particle, they do not decrease with increasing of the energy and could reach several percents for pure QED processes or tens percents in the case of a quark-antiquark jets production. Transverse to the beam direction components of the outgoing particle momenta are assumed to be large compared with the electron (quark) mass. 6 refs., 3 tabs

  20. Investigation of Inclusive CP Asymmetries in B$^{0}$ Decays

    CERN Document Server

    Barate, R; Ghez, P; Goy, C; Lees, J P; Merle, E; Minard, M N; Pietrzyk, B; Bravo, S; Casado, M P; Chmeissani, M; Crespo, J M; Fernández, E; Fernández-Bosman, M; Garrido, L; Graugès-Pous, E; Martínez, M; Merino, G; Miquel, R; Mir, L M; Pacheco, A; Ruiz, H; Colaleo, A; Creanza, D; De Palma, M; Iaselli, Giuseppe; Maggi, G; Maggi, M; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Abbaneo, D; Boix, G; Buchmüller, O L; Cattaneo, M; Cerutti, F; Dissertori, G; Drevermann, H; Forty, Roger W; Frank, M; Greening, T C; Hansen, J B; Harvey, J; Janot, P; Jost, B; Lehraus, Ivan; Mato, P; Minten, Adolf G; Moutoussi, A; Ranjard, F; Rolandi, Luigi; Schlatter, W D; Schmitt, M; Schneider, O; Spagnolo, P; Tejessy, W; Teubert, F; Tournefier, E; Wright, A E; Ajaltouni, Ziad J; Badaud, F; Chazelle, G; Deschamps, O; Falvard, A; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Petersen, B; Wäänänen, A; Daskalakis, G; Kyriakis, A; Markou, C; Simopoulou, Errietta; Vayaki, Anna; Blondel, A; Bonneaud, G R; Brient, J C; Rougé, A; Rumpf, M; Swynghedauw, M; Verderi, M; Videau, H L; Focardi, E; Parrini, G; Zachariadou, K; Antonelli, A; Antonelli, M; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Chiarella, V; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Passalacqua, L; Pepé-Altarelli, M; Halley, A W; Lynch, J G; Negus, P; O'Shea, V; Raine, C; Teixeira-Dias, P; Thompson, A S; Cavanaugh, R J; Dhamotharan, S; Geweniger, C; Hanke, P; Hansper, G; Hepp, V; Kluge, E E; Putzer, A; Sommer, J; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Dornan, Peter J; Girone, M; Marinelli, N; Sedgbeer, J K; Thompson, J C; Thomson, E; Ghete, V M; Girtler, P; Kneringer, E; Kuhn, D; Rudolph, G; Bowdery, C K; Buck, P G; Finch, A J; Foster, F; Hughes, G; Jones, R W L; Robertson, N A; Giehl, I; Jakobs, K; Kleinknecht, K; Quast, G; Renk, B; Rohne, E; Sander, H G; Wachsmuth, H W; Zeitnitz, C; Bonissent, A; Carr, J; Coyle, P; Leroy, O; Payre, P; Rousseau, D; Talby, M; Aleppo, M; Ragusa, F; Dietl, H; Ganis, G; Heister, A; Hüttmann, K; Lütjens, G; Mannert, C; Männer, W; Moser, H G; Schael, S; Settles, Ronald; Stenzel, H; Wiedenmann, W; Wolf, G; Azzurri, P; Boucrot, J; Callot, O; Chen, S; Cordier, A; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Jacholkowska, A; Le Diberder, F R; Lefrançois, J; Lutz, A M; Schune, M H; Veillet, J J; Videau, I; Yuan, C; Zerwas, D; Bagliesi, G; Boccali, T; Calderini, G; Ciulli, V; Foà, L; Giassi, A; Ligabue, F; Messineo, A; Palla, Fabrizio; Rizzo, G; Sanguinetti, G; Sciabà, A; Sguazzoni, G; Tenchini, Roberto; Venturi, A; Verdini, P G; Blair, G A; Cowan, G D; Green, M G; Medcalf, T; Strong, J A; Von Wimmersperg-Töller, J H; Clifft, R W; Edgecock, T R; Norton, P R; Tomalin, I R; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Black, S N; Dann, J H; Johnson, R P; Kim, H Y; Konstantinidis, N P; Litke, A M; McNeil, M A; Taylor, G; Booth, C N; Cartwright, S L; Combley, F; Lehto, M H; Thompson, L F; Affholderbach, K; Böhrer, A; Brandt, S; Grupen, Claus; Misiejuk, A; Prange, G; Sieler, U; Giannini, G; Gobbo, B; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Cranmer, K; Elmer, P; Ferguson, D P S; Gao, Y; González, S; Hayes, O J; Hu, H; Jin, S; Kile, J; McNamara, P A; Nielsen, J; Orejudos, W; Pan, Y B; Saadi, Y; Scott, I J; Walsh, J; Wu Sau Lan; Wu, X; Zobernig, G

    2001-01-01

    A search for CP violating effects in the mixing of neutral B mesons is performed using a sample of 4.1 million hadronic Z decays collected with the ALEPH detector from 1991 to 1995. By studying time-dependent asymmetries in flavour-tagged samples of semileptonic and fully inclusive b-hadron decays, two measurements of the semileptonic asymmetry a_cp are extracted. No evidence for CP violation is observed, and the combined value a_cp = -0.013 +- 0.026 is obtained.

  1. Normal Spin Asymmetries in Elastic Electron-Proton Scattering

    International Nuclear Information System (INIS)

    M. Gorchtein; P.A.M. Guichon; M. Vanderhaeghen

    2004-01-01

    We discuss the two-photon exchange contribution to observables which involve lepton helicity flip in elastic lepton-nucleon scattering. This contribution is accessed through the single spin asymmetry for a lepton beam polarized normal to the scattering plane. We estimate this beam normal spin asymmetry at large momentum transfer using a parton model and we express the corresponding amplitude in terms of generalized parton distributions. We further discuss this observable in the quasi-RCS kinematics which may be dominant at certain kinematical conditions and find it to be governed by the photon helicity-flip RCS amplitudes

  2. Normal Spin Asymmetries in Elastic Electron-Proton Scattering

    International Nuclear Information System (INIS)

    Gorchtein, M.; Guichon, P.A.M.; Vanderhaeghen, M.

    2005-01-01

    We discuss the two-photon exchange contribution to observables which involve lepton helicity flip in elastic lepton-nucleon scattering. This contribution is accessed through the single spin asymmetry for a lepton beam polarized normal to the scattering plane. We estimate this beam normal spin asymmetry at large momentum transfer using a parton model and we express the corresponding amplitude in terms of generalized parton distributions. We further discuss this observable in the quasi-RCS kinematics which may be dominant at certain kinematical conditions and find it to be governed by the photon helicity-flip RCS amplitudes

  3. Asymmetric dark matter, baryon asymmetry and lepton number violation

    OpenAIRE

    Frandsen, Mads T.; Hagedorn, Claudia; Huang, Wei-Chih; Molinaro, Emiliano; Päs, Heinrich

    2018-01-01

    We study the effect of lepton number violation (LNV) on baryon asymmetry, generated in the early Universe, in the presence of a dark sector with a global symmetry U(1)X , featuring asymmetric dark matter (ADM). We show that in general LNV, observable at the LHC or in neutrinoless double beta decay experiments, cannot wash out a baryon asymmetry generated at higher scales, unlike in scenarios without such dark sector. An observation of LNV at the TeV scale may thus support ADM scenarios. Consi...

  4. 75 FR 32747 - Prestressed Concrete Steel Wire Strand from Mexico: Rescission of Antidumping Duty Administrative...

    Science.gov (United States)

    2010-06-09

    ... DEPARTMENT OF COMMERCE INTERNATIONAL TRADE ADMINISTRATION [A-201-831] Prestressed Concrete Steel Wire Strand from Mexico: Rescission of Antidumping Duty Administrative Review AGENCY: Import... request an administrative review of the antidumping duty order on prestressed concrete steel wire strand...

  5. Inter-strand resistance measurements in the termination of the ITER SULTAN samples

    International Nuclear Information System (INIS)

    Cau, F; Bruzzone, P

    2009-01-01

    In cabled conductors a perfect uniformity of the current among the strands is hardly reached, due to the non-homogeneity of the contact resistance distribution between the strands and the copper of the electrical terminations. In the case of large current unbalance, the overloaded strands hit the critical surface at high field early, developing a current sharing voltage, which drives the redistribution of the current, mainly in the electrical terminations where the inter-strand resistance is lower than in the high field conductor. If the inter-strand resistance in the termination is low, the voltage levels are sufficiently low to allow an effective redistribution of the current to the less loaded strands. The inter-strand resistance of three different termination layouts of ITER short length samples is measured to make a database available which can be used to qualify the layout of the joints and their capability of redistributing the current among the strands.

  6. Corrosion characteristics of post-tensioning strands in ungrouted ducts : summary.

    Science.gov (United States)

    2011-01-01

    To prevent corrosion of post-tensioning strands, FDOT construction specifications currently require post-tensioning ducts to be grouted within seven calendar days of strand installation. This period challenges construction schedules on large projects...

  7. IHF-independent assembly of the Tn10 strand transfer transpososome: implications for inhibition of disintegration

    OpenAIRE

    Stewart, Barry J.; Wardle, Simon J.; Haniford, David B.

    2002-01-01

    The frequency of DNA transposition in transposition systems that employ a strand transfer step may be significantly affected by the occurrence of a disintegration reaction, a reaction that reverses the strand transfer event. We have asked whether disintegration occurs in the Tn10 transposition system. We show that disintegration substrates (substrates constituting one half of the strand transfer product) are assembled into a transpososome that mimics the strand transfer intermediate. This str...

  8. DNA strand breaks, repair, and survival in x-irradiated mammalian cells

    International Nuclear Information System (INIS)

    Dugle, D.L.; Gillespie, C.J.; Chapman, J.D.

    1976-01-01

    The yields of unrepairable single- and double-strand breaks in the DNA of x-irradiated Chinese hamster cells were measured by low-speed neutral and alkaline sucrose density gradient sedimentation in order to investigate the relation between these lesions and reproductive death. After maximal single-strand rejoining, at all doses, the number of residual single-strand breaks was twice the number of residual double-strand breaks. Both double-strand and unrepairable single-strand breaks were proportional to the square of absorbed dose, in the range 10-50 krad. No rejoining of double-strand breaks was observed. These observations suggest that, in mammalian cells, most double-strand breaks are not repairable, while all single-strand breaks are repaired except those that are sufficiently close on complementary strands to constitute double-strand breaks. Comparison with cell survival measurements at much lower doses suggests that loss of reproductive capacity corresponds to induction of approximately one double-strand break

  9. Oriented-strand-board- the wave of the future- for the building trade

    Science.gov (United States)

    Linda Ashton

    1984-01-01

    Move over, plywood. Oriented-strand board is here. It's less expensive. It's as durable. It has as many uses. And it is the wave of the future. "Oriented-strand board is a direct substitute for plywood" said Jerry Buckner, plant manager for the Martco oriented-strand board plant in Lemoyen. OSB, as it is commonly called, is a structural panel made...

  10. Probing electronic coupling between adenine bases in RNA strands from synchrotron radiation circular dichroism experiments

    DEFF Research Database (Denmark)

    Nielsen, Lisbeth Munksgård; Hoffmann, Søren Vrønning; Nielsen, Steen Brøndsted

    2012-01-01

    Circular dichroism spectra (176–330 nm) of RNA adenine oligomers, (rA)n (n = 1–10, 12, 15, and 20), reveal electronic coupling between two bases in short strands. The number of interacting bases in long strands is more and larger than that reported previously for the corresponding DNA strands....

  11. 77 FR 2958 - Prestressed Concrete Steel Wire Strand From Thailand: Correction to Notice of Opportunity To...

    Science.gov (United States)

    2012-01-20

    ... DEPARTMENT OF COMMERCE International Trade Administration [A-549-820] Prestressed Concrete Steel Wire Strand From Thailand: Correction to Notice of Opportunity To Request Administrative Review AGENCY... prestressed concrete steel wire strand (``PC Strand'') from Thailand. See Antidumping or Countervailing Duty...

  12. Torsional regulation of hRPA-induced unwinding of double-stranded DNA

    NARCIS (Netherlands)

    De Vlaminck, I.; Vidic, I.; Van Loenhout, M.T.J.; Kanaar, R.; Lebbink, J.H.G.; Dekker, C.

    2010-01-01

    All cellular single-stranded (ss) DNA is rapidly bound and stabilized by single stranded DNA-binding proteins (SSBs). Replication protein A, the main eukaryotic SSB, is able to unwind double-stranded (ds) DNA by binding and stabilizing transiently forming bubbles of ssDNA. Here, we study the

  13. Structural features in the HIV-1 repeat region facilitate strand transfer during reverse transcription

    NARCIS (Netherlands)

    Berkhout, B.; Vastenhouw, N. L.; Klasens, B. I.; Huthoff, H.

    2001-01-01

    Two obligatory DNA strand transfers take place during reverse transcription of a retroviral RNA genome. The first strand transfer is facilitated by terminal repeat (R) elements in the viral genome. This strand-transfer reaction depends on base pairing between the cDNA of the 5'R and the 3'R. There

  14. 75 FR 62820 - Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA

    Science.gov (United States)

    2010-10-13

    ... Providers of Synthetic Double- Stranded DNA AGENCY: Department of Health and Human Services, Office of the.... Government has developed Guidance that provides a framework for screening synthetic double-stranded DNA (dsDNA). This document, the Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA...

  15. 75 FR 36678 - Prestressed Concrete Steel Wire Strand From China; Determinations

    Science.gov (United States)

    2010-06-28

    ... prestressed concrete steel wire strand (PC strand), provided for in subheading 7312.10.30 of the Harmonized... Publication 4162 (June 2010), entitled Prestressed Concrete Steel Wire Strand from China: Investigation Nos... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-464 and 731-TA-1160 (Final)] Prestressed...

  16. Measurement and genetics of human subcortical and hippocampal asymmetries in large datasets

    NARCIS (Netherlands)

    Guadalupe, T.M.; Zwiers, M.P.; Teumer, A.; Wittfeld, K.; Arias Vasquez, A.; Hoogman, M.; Hagoort, P.; Fernandez, G.S.E.; Buitelaar, J.K.; Hegenscheid, K.; Volzke, H.; Franke, B.; Fisher, S.E.; Grabe, H.J.; Francks, C.

    2014-01-01

    Functional and anatomical asymmetries are prevalent features of the human brain, linked to gender, handedness, and cognition. However, little is known about the neurodevelopmental processes involved. In zebrafish, asymmetries arise in the diencephalon before extending within the central nervous

  17. Identification of Cis-Acting Elements on Positive-Strand Subgenomic mRNA Required for the Synthesis of Negative-Strand Counterpart in Bovine Coronavirus

    Directory of Open Access Journals (Sweden)

    Po-Yuan Yeh

    2014-07-01

    Full Text Available It has been demonstrated that, in addition to genomic RNA, sgmRNA is able to serve as a template for the synthesis of the negative-strand [(−-strand] complement. However, the cis-acting elements on the positive-strand [(+-strand] sgmRNA required for (−-strand sgmRNA synthesis have not yet been systematically identified. In this study, we employed real-time quantitative reverse transcription polymerase chain reaction to analyze the cis-acting elements on bovine coronavirus (BCoV sgmRNA 7 required for the synthesis of its (−-strand counterpart by deletion mutagenesis. The major findings are as follows. (1 Deletion of the 5'-terminal leader sequence on sgmRNA 7 decreased the synthesis of the (−-strand sgmRNA complement. (2 Deletions of the 3' untranslated region (UTR bulged stem-loop showed no effect on (−-strand sgmRNA synthesis; however, deletion of the 3' UTR pseudoknot decreased the yield of (−-strand sgmRNA. (3 Nucleotides positioned from −15 to −34 of the sgmRNA 7 3'-terminal region are required for efficient (−-strand sgmRNA synthesis. (4 Nucleotide species at the 3'-most position (−1 of sgmRNA 7 is correlated to the efficiency of (−-strand sgmRNA synthesis. These results together suggest, in principle, that the 5'- and 3'-terminal sequences on sgmRNA 7 harbor cis-acting elements are critical for efficient (−-strand sgmRNA synthesis in BCoV.

  18. Radiation dose response of strand breaks in SINPV-DNA

    International Nuclear Information System (INIS)

    Zhang Chunxiang; Luo Daling; Li Mianfeng; Liu Xiaowei; Zeng Rong; Wang Xunzhang

    1995-01-01

    The Spodoplera litura Nuclear Polyhedrosis Viruses (SINPV) is a kind of insectile virus with a simple structure, in which a double helix DNA is encapsulated in a protein coat and there is no function of enzymatic repair. The SINPV samples in dry powdered form held in sealed plastic tube were irradiated by 1-100 kGy gamma rays. The single strand breaks (SSB) and double strand breaks (DSB) induced in SINPV after irradiation were measured by neutral and alkaline agarose gel electrophoresis. A dose-response function combining the responses of one-hit and two-hit events was used to describe the SSB and DSB dose-response curves. It is shown that the SSB are one-hit events and the DSB are the combination of both one-hit, and two-hit events, and two-hit events are predominant in the DSB process

  19. Dynamic protein assembly by programmable DNA strand displacement

    Science.gov (United States)

    Chen, Rebecca P.; Blackstock, Daniel; Sun, Qing; Chen, Wilfred

    2018-03-01

    Inspired by the remarkable ability of natural protein switches to sense and respond to a wide range of environmental queues, here we report a strategy to engineer synthetic protein switches by using DNA strand displacement to dynamically organize proteins with highly diverse and complex logic gate architectures. We show that DNA strand displacement can be used to dynamically control the spatial proximity and the corresponding fluorescence resonance energy transfer between two fluorescent proteins. Performing Boolean logic operations enabled the explicit control of protein proximity using multi-input, reversible and amplification architectures. We further demonstrate the power of this technology beyond sensing by achieving dynamic control of an enzyme cascade. Finally, we establish the utility of the approach as a synthetic computing platform that drives the dynamic reconstitution of a split enzyme for targeted prodrug activation based on the sensing of cancer-specific miRNAs.

  20. DNA single strand break in fibroblast from Down syndrome patients

    International Nuclear Information System (INIS)

    Rozga, B.

    1992-01-01

    The radiosensitivity of tree trisomic (trisomia +21) strains of human fibroblasts to gamma radiation has been investigated in vitro and the causes of induction and repair of single strand DNA breaks in these cells have been estimated. The single strand breaks in DNA of normal and trisomic cells have been found to be ameliorated with an approximately equal efficiency. Repair has been found to be three times slower in trisomic cells compared to their normal relevant, most likely due to their elevated sensitivity to ionizing radiation and the following mortality of trisomic cells, and/or the potential occurrence of a great number of chromosome aberrations in cells irradiated in vitro. (author). 28 refs, 4 figs, 1 tab

  1. Hybrid fur rendering: combining volumetric fur with explicit hair strands

    DEFF Research Database (Denmark)

    Andersen, Tobias Grønbeck; Falster, Viggo; Frisvad, Jeppe Revall

    2016-01-01

    Hair is typically modeled and rendered using either explicitly defined hair strand geometry or a volume texture of hair densities. Taken each on their own, these two hair representations have difficulties in the case of animal fur as it consists of very dense and thin undercoat hairs in combination...... with coarse guard hairs. Explicit hair strand geometry is not well-suited for the undercoat hairs, while volume textures are not well-suited for the guard hairs. To efficiently model and render both guard hairs and undercoat hairs, we present a hybrid technique that combines rasterization of explicitly...... defined guard hairs with ray marching of a prismatic shell volume with dynamic resolution. The latter is the key to practical combination of the two techniques, and it also enables a high degree of detail in the undercoat. We demonstrate that our hybrid technique creates a more detailed and soft fur...

  2. Prevention of Potential Falls of Elderly Healthy Women: Gait Asymmetry

    Science.gov (United States)

    Seo, Jung-suk; Kim, Sukwon

    2014-01-01

    The study attempted to see if exercise training would alleviate gait asymmetry between nondominant and dominant legs, thus, eliminate the likelihood of slips. The present study provided 18 older adults exercise training for eight weeks and evaluated kinematics and ground reaction forces (GRFs) in both legs. Participants were randomly assigned to…

  3. Study of the s - s bar asymmetry in the proton

    Science.gov (United States)

    Goharipour, Muhammad

    2018-05-01

    The study of s - s bar asymmetry is essential to better understand of the structure of nucleon and also the perturbative and nonperturbative mechanisms for sea quark generation. Actually, the nature and dynamical origins of this asymmetry have always been an interesting subject to research both experimentally and theoretically. One of the most powerful models can lead to s - s bar asymmetry is the meson-baryon model (MBM). In this work, using a simplified configuration of this model suggested by Pumplin, we calculate the s - s bar asymmetry for different values of cutoff parameter Λ, to study the dependence of model to this parameter and also to estimate the theoretical uncertainty imposed on the results due to its uncertainty. Then, we study the evolution of distributions obtained both at next-to-leading order (NLO) and next-to-next-to-leading order (NNLO) using different evolution schemes. It is shown that the evolution of the intrinsic quark distributions from a low initial scale, as suggested by Chang and Pang, is not a good choice at NNLO using variable flavor number scheme (VFNS).

  4. Age-Related Differences in Bilateral Asymmetry in Cycling Performance

    Science.gov (United States)

    Liu, Ting; Jensen, Jody L.

    2012-01-01

    Bilateral asymmetry, a form of limb laterality in the context of moving two limbs, emerges in childhood. Children and adults show lateral preference in tasks that involve the upper and lower limbs. The importance of research in limb laterality is the insight it could provide about lateralized functions of the cerebral hemispheres. Analyzing…

  5. On the conception of fundamental time asymmetries in physics

    International Nuclear Information System (INIS)

    Wohlfarth, Daniel

    2013-01-01

    The investigation is divided in 7 chapters and aims to argue for the realizability of a new conception of 'fundamental time asymmetries' in physics. After an introduction (chapter 1) in the field of interest, the investigation continues by developing a conception of fundamentality for time asymmetries in chapter 2. Chapter 3 shows that this conception is realized in classical cosmology and chapter 4 demonstrates, by taking in to account the result from chapter 3, that classical electrodynamics is understandable as a time asymmetric theory. Chapter 5 focuses on time asymmetries in quantum cosmology as well as quantum thermodynamics and demonstrates - as in the classical case - that a fundamental time asymmetry is imbedded in those fields. The considerations, contained in chapter 6, are focused on non relativistic quantum mechanics (NRQM). Here the main aim is to demonstrate that NRQM can be understood as a time asymmetric theory - even without using the measurement-process for that purpose. Chapter 7 summarized the main arguments and conclusions.

  6. Sex-specific asymmetry in eye development in interspecific hybrids ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 94; Issue 3. Sex-specific asymmetry in eye development in interspecific hybrids in the Drosophila bipectinata species complex. Bashisth N. Singh Parul Banerjee. Research Note Volume 94 Issue 3 September 2015 pp 493-495 ...

  7. Nonlinear growth dynamics and the origin of fluctuating asymmetry

    Science.gov (United States)

    Emlen, J.M.; Freeman, D.C.; Graham, J.H.

    1993-01-01

    The nonlinear, complex nature of biosynthesis magnifies the impacts of small, random perturbations on organism growth, leading to distortions in adaptive allometries and, in particular, to fluctuating asymmetry. These distortions can be partly checked by cell-cell and inter-body part feedback during growth and development, though the latter mechanism also may lead to complex patterns in right-left asymmetry. Stress can be expected to increase the degree to which random growth perturbations are magnified and may also result in disruption of the check mechanisms, thus exaggerating fluctuating asymmetry.The processes described not only provide one explanation for the existence of fluctuating asymmetry and its augmentation under stress, but suggest additional effects of stress as well. Specifically, stress is predicted to lead to decreased fractal dimension of bone sutures and branching structures in animals, and in increased dimension of growth trace patterns such as those found in mollusc shells and fish otoliths and scales.A basic yet broad primer on fractals and chaos is provided as background for the theoretical development in this manuscript.

  8. Comparing Neutron Star Kicks to Supernova Remnant Asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Holland-Ashford, Tyler; Lopez, Laura A. [The Ohio State University Department of Astronomy, 140 W 18th Avenue, Columbus, OH 43201 (United States); Auchettl, Katie [The Ohio State University Center for Cosmology and Astro-particle Physics, 191 West Woodruff Avenue, Columbus, OH 43210 (United States); Temim, Tea [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Ramirez-Ruiz, Enrico, E-mail: holland-ashford.1@osu.edu [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States)

    2017-07-20

    Supernova explosions are inherently asymmetric and can accelerate new-born neutron stars (NSs) to hundreds of km s{sup −1}. Two prevailing theories to explain NS kicks are ejecta asymmetries (e.g., conservation of momentum between NS and ejecta) and anisotropic neutrino emission. Observations of supernova remnants (SNRs) can give us insights into the mechanism that generates these NS kicks. In this paper, we investigate the relationship between NS kick velocities and the X-ray morphologies of 18 SNRs observed with the Chandra X-ray Observatory and the Röntgen Satellite ( ROSAT ). We measure SNR asymmetries using the power-ratio method (a multipole expansion technique), focusing on the dipole, quadrupole, and octupole power ratios. Our results show no correlation between the magnitude of the power ratios and NS kick velocities, but we find that for Cas A and G292.0+1.8, whose emission traces the ejecta distribution, their NSs are preferentially moving opposite to the bulk of the X-ray emission. In addition, we find a similar result for PKS 1209–51, CTB 109, and Puppis A; however, their emission is dominated by circumstellar/interstellar material, so their asymmetries may not reflect their ejecta distributions. Our results are consistent with the theory that NS kicks are a consequence of ejecta asymmetries as opposed to anisotropic neutrino emission. In the future, additional observations to measure NS proper motions within ejecta-dominated SNRs are necessary to robustly constrain the NS kick mechanism.

  9. Neutrino-antineutrino asymmetry around rotating black holes

    Indian Academy of Sciences (India)

    important effects and hence can be constrained by Big Bang nucleosynthesis and power spectrum of cosmic microwave background, it becomes an important issue by itself to study new mechanisms which can generate neutrino asymmetry specially in the present epoch. When Dirac neutrinos propagate in gravitational ...

  10. Isospin analysis of CP asymmetries in B decays

    International Nuclear Information System (INIS)

    Gronau, M.; London, D.

    1990-09-01

    There is some theoretical uncertainty in the predictions for CP violating hadronic asymmetries in neutral B decays to CP eigenstates due to the existence of penguin diagrams. Using isospin relatins, we show that it is possible to remove this uncertainty for the decays B d 0 → ππ, up to a 4-fold ambiguity. (orig.)

  11. Baryon - antibaryon asymmetry in central rapidity region at LHC ALICE

    International Nuclear Information System (INIS)

    Broz, M.

    2008-01-01

    Study of asymmetry in number of baryons and antibaryons in central rapidity region is important for clarification of baryon number carriers character. Effect we are interested in is small, can be hidden by systematical processes of particle track reconstruction and identification. To make corrections on these effects is the aim of this thesis. (author)

  12. On the conception of fundamental time asymmetries in physics

    Energy Technology Data Exchange (ETDEWEB)

    Wohlfarth, Daniel

    2013-02-05

    The investigation is divided in 7 chapters and aims to argue for the realizability of a new conception of 'fundamental time asymmetries' in physics. After an introduction (chapter 1) in the field of interest, the investigation continues by developing a conception of fundamentality for time asymmetries in chapter 2. Chapter 3 shows that this conception is realized in classical cosmology and chapter 4 demonstrates, by taking in to account the result from chapter 3, that classical electrodynamics is understandable as a time asymmetric theory. Chapter 5 focuses on time asymmetries in quantum cosmology as well as quantum thermodynamics and demonstrates - as in the classical case - that a fundamental time asymmetry is imbedded in those fields. The considerations, contained in chapter 6, are focused on non relativistic quantum mechanics (NRQM). Here the main aim is to demonstrate that NRQM can be understood as a time asymmetric theory - even without using the measurement-process for that purpose. Chapter 7 summarized the main arguments and conclusions.

  13. Memory Asymmetry of Forward and Backward Associations in Recognition Tasks

    Science.gov (United States)

    Yang, Jiongjiong; Zhao, Peng; Zhu, Zijian; Mecklinger, Axel; Fang, Zhiyong; Li, Han

    2013-01-01

    There is an intensive debate on whether memory for serial order is symmetric. The objective of this study was to explore whether associative asymmetry is modulated by memory task (recognition vs. cued recall). Participants were asked to memorize word triples (Experiments 1-2) or pairs (Experiments 3-6) during the study phase. They then recalled…

  14. Antinatalism, Asymmetry, and an Ethic of Prima Facie Duties ...

    African Journals Online (AJOL)

    Benatar's central argument for antinatalism develops an asymmetry between the pain and pleasure in a potential life. I am going to present an alternative route to the antinatalist conclusion. I argue that duties require victims and that as a result there is no duty to create the pleasures contained within a prospective life but a ...

  15. Double spin asymmetry in exclusive rho(0) muoproduction at COMPASS

    Czech Academy of Sciences Publication Activity Database

    Alekseev, M.; Alexakhin, V. Yu.; Alexandrov, Yu.; Alexeev, G. D.; Amoroso, A.; Arbuzov, A.; Badelek, B.; Balestra, F.; Ball, J.; Baum, G.; Barth, J.; Bedfer, Y.; Bernet, C.; Bertini, R.; Bettinelli, M.; Birsa, R.; Bisplinghoff, J.; Bordalo, P.; Bradamante, F.; Bravar, A.; Bressan, A.; Brona, G.; Burtin, E.; Bussa, M.; Chapiro, A.; Chiosso, M.; Cicuttin, A.; Colantoni, M.; Costa, S.; Crespo, M.; d'Hose, N.; Dalla Torre, S.; Das, S.; Dasgupta, S. S.; De Masi, R.; Dedek, N.; Denisov, O.; Dhara, L.; Diaz, V.; Dinkelbach, A.; Donskov, S.; Dorofeev, V.; Doshita, N.; Duic, V.; Dünnweber, W.; Eversheim, P.; Eyrich, W.; Fabro, M.; Faessler, M.; Falaleev, V.; Ferrero, A.; Ferrero, L.; Finger, M.; Finger jr., M.; Fischer, H.; Franco, C.; Franz, J.; Friedrich, J.; Frolov, V.; Garfagnini, R.; Gautheron, F.; Gavrichtchouk, O.; Gazda, R.; Gerassimov, S.; Geyer, R.; Giorgi, M.; Gobbo, B.; Goertz, S.; Gorin, A. M.; Grabmüller, S.; Grajek, O.; Grasso, A.; Grube, B.; Gushterski, R.; Guskov, A.; Haas, F.; Hannappel, J.; von Harrach, D.; Hasegawa, T.; Heckmann, J.; Hedicke, S.; Heinsius, F.; Hermann, R.; Hess, C.; Hinterberger, F.; von Hodenberg, M.; Horikawa, N.; Horikawa, S.; Ilgner, C.; Ioukaev, A.; Ishimoto, S.; Ivanov, O.; Ivanshin, Yu.; Iwata, T.; Jahn, R.; Janata, A.; Jasinski, P.; Joosten, R.; Jouravlev, N. I.; Kabuss, E.; Kang, D.; Ketzer, B.; Khaustov, G.; Khokhlov, Y.; Kisselev, Y.; Klein, F.; Klimaszewski, K.; Koblitz, S.; Koivuniemi, J.; Kolosov, V.; Komissarov, E.; Kondo, K.; Königsmann, K.; Konorov, I.; Konstantinov, V.; Korentchenko, A.; Korzenev, A.; Kotzinian, A.; Koutchinski, N.; Kouznetsov, O.; Kravchuk, N.; Kral, A.; Kroumchtein, Z.; Kuhn, R.; Kunne, F.; Kurek, K.; Ladygin, M.; Lamanna, M.; Le Goff, J.; Lednev, A.; Lehmann, A.; Lichtenstadt, J.; Liska, T.; Ludwig, I.; Maggiora, A.; Maggiora, M.; Magnon, A.; Mallot, G.; Mann, A.; Marchand, C.; Marroncle, J.; Martin, A.; Marzec, J.; Massmann, F.; Matsuda, T.; Maximov, A.; Meyer, W.; Mielech, A.; Mikhailov, Y.; Moinester, M.; Mutter, M.; Nähle, O.; Nagaytsev, A.; Nagel, T.; Nassalski, J.; Neliba, S.; Nerling, F.; Neubert, S.; Neyret, D.; Nikolaenko, V.; Nikolaev, K.; Olshevsky, A.; Ostrick, M.; Padee, A.; Pagano, P.; Panebianco, S.; Panknin, R.; Panzieri, D.; Paul, S.; Pawlukiewicz-Kaminska, B.; Peshekhonov, D.; Peshekhonov, V.; Piragino, G.; Platchkov, S.; Pochodzalla, J.; Polak, J.; Polyakov, V.; Pretz, J.; Procureur, S.; Quintans, C.; Rajotte, J.; Rapatsky, V.; Ramos, S.; Reicherz, G.; Richter, A.; Robinet, F.; Rocco, E.; Rondio, E.; Rozhdestvensky, A.; Ryabchikov, D.; Samoylenko, V.; Sandacz, A.; Santos, H.; Sapozhnikov, M.; Sarkar, S.; Savin, I.; Schiavon, P.; Schill, C.; Schmitt, L.; Schönmeier, P.; Schröder, W.; Shevchenko, O.; Siebert, H.; Silva, L.; Sinha, L.; Sissakian, A.; Slunecka, M.; Smirnov, G.; Sosio, S.; Sozzi, F.; Sugonyaev, V.; Srnka, Aleš; Stinzing, F.; Stolarski, M.; Sulc, M.; Sulej, R.; Takabayashi, N.; Tchalishev, V.; Tessaro, S.; Tessarotto, F.; Teufel, A.; Tkatchev, L.; Venugopal, G.; Virius, M.; Vlassov, N.; Vossen, A.; Webb, R.; Weise, E.; Weitzel, Q.; Windmolders, R.; Wirth, S.; Wislicki, W.; Zaremba, K.; Zavertyaev, M.; Zemlyanichkina, E.; Zhao, J.; Ziegler, R.; Zvyagin, A.

    2007-01-01

    Roč. 52, č. 2 (2007), s. 255-265 ISSN 1434-6044 R&D Projects: GA MŠk ME 492 Institutional research plan: CEZ:AV0Z20650511 Keywords : double spin asymmetry * polarized deuterons * scattering * COMPASS Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 3.255, year: 2007

  16. Asymmetry in the Perception of Friendship in Students Groups

    Science.gov (United States)

    Lancieri, Luigi

    2017-01-01

    Several studies point out the link between sociability and academic results. In this paper, we highlight a phenomenon of asymmetry in the perception of friendship. This occurs when a student think he has more or less friends than he really has. We present an experimental method that allows us to analyze this question in relation with the academic…

  17. Asymmetry in Nature-Discrete Symmetries in Particle Physics and ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 3. Asymmetry in Nature - Discrete Symmetries in Particle Physics and their Violation - Background and ... Theoretical Studies, Indian Institute of Science, Bangalore 560012, India. Indian Institute of Technology, Chennai. Aligarh Muslim University.

  18. Handling power-asymmetry in interactions with infants

    DEFF Research Database (Denmark)

    Demuth, Carolin

    2013-01-01

    socio-cultural communities deal with power asymmetry in interactions with 3-months old infants. The study consists of a microanalysis of videotaped free play mother-infant interactions from 20 middle class families in Muenster, Germany and 20 traditional farming Nso families in Kikaikelaki, Cameroon...

  19. A New Measure Of Bivariate Asymmetry And Its Evaluation

    International Nuclear Information System (INIS)

    Ferreira, Flavio Henn; Kolev, Nikolai Valtchev

    2008-01-01

    In this paper we propose a new measure of bivariate asymmetry, based on conditional correlation coefficients. A decomposition of the Pearson correlation coefficient in terms of its conditional versions is studied and an example of application of the proposed measure is given.

  20. Determining asymmetry of roll-over shapes in prosthetic walking

    NARCIS (Netherlands)

    Curtze, C.; Otten, Bert; Hof, A.L.; Postema, K.

    2011-01-01

    How does the inherent asymmetry of the locomotor system in people with lower-limb amputation affect the ankle-foot roll-over shape of prosthetic walking? In a single-case design, we evaluated the walking patterns of six people with lower-limb amputation (3 transtibial and 3 transfemoral) and three

  1. Network Asymmetries and Access Pricing in Cellular Telecommunications

    NARCIS (Netherlands)

    V. Kocsis

    2005-01-01

    textabstractNetwork shares and retail prices are not symmetric in the telecommunications market with multiple bottlenecks which give rise to new questions of access fee regulation. In this paper we consider a model with two types of asymmetry arising from different entry timing, i.e. a larger

  2. Beta asymmetry parameter in the decay of In-114

    Czech Academy of Sciences Publication Activity Database

    Wauters, F.; De Leebeeck, V.; Kraev, I.; Tandecki, M.; Traykov, E.; Van Gorp, S.; Severijns, N.; Zákoucký, Dalibor

    2009-01-01

    Roč. 80, č. 6 (2009), 062501/1-062501/5 ISSN 0556-2813 Institutional research plan: CEZ:AV0Z10480505 Keywords : beta decay * left -right asymmetry * nuclear oreintation Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 3.477, year: 2009

  3. Critical asymmetry in renormalization group theory for fluids.

    Science.gov (United States)

    Zhao, Wei; Wu, Liang; Wang, Long; Li, Liyan; Cai, Jun

    2013-06-21

    The renormalization-group (RG) approaches for fluids are employed to investigate critical asymmetry of vapour-liquid equilibrium (VLE) of fluids. Three different approaches based on RG theory for fluids are reviewed and compared. RG approaches are applied to various fluid systems: hard-core square-well fluids of variable ranges, hard-core Yukawa fluids, and square-well dimer fluids and modelling VLE of n-alkane molecules. Phase diagrams of simple model fluids and alkanes described by RG approaches are analyzed to assess the capability of describing the VLE critical asymmetry which is suggested in complete scaling theory. Results of thermodynamic properties obtained by RG theory for fluids agree with the simulation and experimental data. Coexistence diameters, which are smaller than the critical densities, are found in the RG descriptions of critical asymmetries of several fluids. Our calculation and analysis show that the approach coupling local free energy with White's RG iteration which aims to incorporate density fluctuations into free energy is not adequate for VLE critical asymmetry due to the inadequate order parameter and the local free energy functional used in the partition function.

  4. Asymmetry of critical closing pressure following head injury

    OpenAIRE

    Kumar, A; Schmidt, E; Hiler, M; Smielewski, P; Pickard, J; Czosnyka, M

    2005-01-01

    Objective: Critical closing pressure (CCP) is the arterial pressure below which the vessels collapse. Hypothetically it is the sum of intracranial pressure (ICP) and vessel wall tension in the cerebral circulation. This study investigated transhemispherical asymmetry of CCP by studying its correlation with radiological findings on computed tomography (CT) scans in head injury patients.

  5. Toroidal asymmetries in divertor impurity influxes in NSTX

    Directory of Open Access Journals (Sweden)

    F. Scotti

    2017-08-01

    Full Text Available Toroidal asymmetries in divertor carbon and lithium influxes were observed in NSTX, due to toroidal differences in surface composition, tile leading edges, externally-applied three-dimensional (3D fields and toroidally-localized edge plasma modifications due to radio frequency heating. Understanding toroidal asymmetries in impurity influxes is critical for the evaluation of total impurity sources, often inferred from measurements with a limited toroidal coverage. The toroidally-asymmetric lithium deposition induced asymmetries in divertor lithium influxes. Enhanced impurity influxes at the leading edge of divertor tiles were the main cause of carbon toroidal asymmetries and were enhanced during edge localized modes. Externally-applied 3D fields led to strike point splitting and helical lobes observed in divertor impurity emission, but marginal changes to the toroidally-averaged impurity influxes. Power coupled to the scrape-off layer SOL plasma during radio frequency (RF heating of H-mode discharges enhanced impurity influxes along the non-axisymmetric divertor footprint of flux tubes connecting to plasma in front of the RF antenna.

  6. [Management of Chinese materia medica market based on information asymmetry].

    Science.gov (United States)

    Yang, Guang; Wang, Nuo; Guo, Lan-Ping; Wang, Yong-Yan; Huang, Lu-Qi; Liu, Jin-Xin

    2013-12-01

    Pharmaceutical market is a typical market with information asymmetry, and which can lead to "lemons" problem. In all developed countries, firms must receive regulatory approval to market a pharmaceutical product. Such administrative department including SFDA, EMA, FDA and so on. Chinese materia medica is a special part of pharmaceutical market in China. The management of Chinese materia medica is a special challenge in China.

  7. Asymmetry of wind waves studied in a laboratory tank

    Directory of Open Access Journals (Sweden)

    I. A. Leykin

    1995-01-01

    Full Text Available Asymmetry of wind waves was studied in laboratory tank tinder varied wind and fetch conditions using both bispectral analysis of wave records and third-order statistics of the surface elevation. It is found skewness S (the normalized third-order moment of surface elevation describing the horizontal asymmetry waves varies only slightly with the inverse wave u*/Cm (where u* is the air friction velocity and Cm is phase speed of the dominant waves. At the same time asymmetry A, which is determined from the Hilbert transform of the wave record and characterizes the skewness of the rate of change of surface elevation, increase consistently in magnitude with the ratio u*/Cm. This suggests that nonlinear distortion of the wave profile determined by the degree of wind forcing and is a sensitive indicator of wind-wave interaction processes. It is shown that the asymmetric profile of waves can described within the frameworks of the nonlinear nonspectral concept (Plate, 1972; Lake and Yuen, 197 according to which the wind-wave field can be represented as a coherent bound-wave system consisting mainly of dominant component w. and its harmonics propagating with the same speed C. , as observed by Ramamonjiaris and Coantic (1976. The phase shift between o. harmonics is found and shown to increase with the asymmetry of the waves.

  8. Asymmetry of wind waves studied in a laboratory tank

    Science.gov (United States)

    Ileykin, L. A.; Donelan, M. A.; Mellen, R. H.; McLaughlin, D. J.

    1995-03-01

    Asymmetry of wind waves was studied in laboratory tank tinder varied wind and fetch conditions using both bispectral analysis of wave records and third-order statistics of the surface elevation. It is found skewness S (the normalized third-order moment of surface elevation describing the horizontal asymmetry waves) varies only slightly with the inverse wave u*/Cm (where u* is the air friction velocity and Cm is phase speed of the dominant waves). At the same time asymmetry A, which is determined from the Hilbert transform of the wave record and characterizes the skewness of the rate of change of surface elevation, increase consistently in magnitude with the ratio u*/Cm. This suggests that nonlinear distortion of the wave profile determined by the degree of wind forcing and is a sensitive indicator of wind-wave interaction processes. It is shown that the asymmetric profile of waves can described within the frameworks of the nonlinear nonspectral concept (Plate, 1972; Lake and Yuen, 197 according to which the wind-wave field can be represented as a coherent bound-wave system consisting mainly of dominant component w. and its harmonics propagating with the same speed C. , as observed by Ramamonjiaris and Coantic (1976). The phase shift between o). harmonics is found and shown to increase with the asymmetry of the waves.

  9. Asymmetry and the shift of the Compton profile

    International Nuclear Information System (INIS)

    Chatterjee, B.K.; Roy, S.C.; Suric, T.; LaJohn, L.A.; Pratt, R.H.

    2007-01-01

    We show that the conventionally defined asymmetry of the Compton profile (CP) is, to a large extent, simply a shift of CP. Compton scattering is widely used in studying the electron momentum distribution (EMD) of complex systems. Extraction of information about the EMD is based on an impulse approximation (IA) description of the process. In IA the scattering from bound electrons is described as scattering from the EMD of free electrons. Most often the angular and energy distributions of scattered photons (doubly differential cross sections (DDCS)) is measured and presented in terms of CP, which is just the DDCS normalized by a kinematical factor. The deviations of measured CP from the IA results are conventionally described as an asymmetry of CP about the IA peak position. IA predicts CP to be symmetric. We have examined the discrepancy between IA predictions (and the corresponding relativistic version of IA, RIA) and more rigorous approaches (A 2 and S-matrix), using independent particle approximations for the description of the bound state of electrons. In the nonrelativistic region (in which many measurements of CP are performed) we find that the conventional asymmetry can largely be understood as the shift of the peak position. The true asymmetry with respect to the shifted peak position is in fact much smaller. RIA has similar properties to IA, except that for atoms with high nuclear charge the p → .A → interaction may modify the shift and limit the utility of description as a shift

  10. The Matter-Antimatter Asymmetry of the Universe

    Science.gov (United States)

    Stecker, F. W.; White, Nicholas E. (Technical Monitor)

    2002-01-01

    I will give here an overview of the present observational and theoretical situation regarding the question of the matter-antimatter asymmetry of the universe and the related question of the existence of antimatter on a cosmological scale. I will also give a simple discussion of the role of CP (charge conjugation parity) violation in this subject.

  11. Targeting abnormal DNA double strand break repair in cancer

    OpenAIRE

    Rassool, Feyruz V.; Tomkinson, Alan E.

    2010-01-01

    A major challenge in cancer treatment is the development of therapies that target cancer cells with little or no toxicity to normal tissues and cells. Alterations in DNA double strand break (DSB) repair in cancer cells include both elevated and reduced levels of key repair proteins and changes in the relative contributions of the various DSB repair pathways. These differences can result in increased sensitivity to DSB-inducing agents and increased genomic instability. The development of agent...

  12. Turbulent Flow Validation in the Helios Strand Solver

    Science.gov (United States)

    2014-01-07

    line Gauss - Seidel (GS) methods are employed to solve this system, where contributions along strands are collected to form a tridiagonal system. To...Qk ) . (50) Upon convergence of the linear iterations in l, the linear system of Equation 48 is satisfied. At that point, the next pseudo-time step in...k proceeds. When the pseudo-time iterations converge , then the residual equation R(Q) is satisfied for a given physical time station. All Jacobian

  13. Five strands of math tasks big book : grades pk-2

    CERN Document Server

    Reed, Nat; Forest, Chris

    2009-01-01

    For grades PK-2, our Common Core State Standards-based resource meets the five strands of math concepts addressed by the NCTM standards and encourages the students to learn and review the concepts in unique ways. Included are challenging problem-solving tasks which will push the boundaries of critical thought and demonstrate to students the importance of mathematical problems in Number & Operations, Geometry, Measurement, Data Analysis & Probability and Algebra using real world situations.

  14. Five strands of math drills big book : grades PK-2

    CERN Document Server

    Reed, Nat; Forest, Chris

    2011-01-01

    For grades PK-2, our Common Core State Standards-based resource meets the five strands of math concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. Included are warm-up and timed drill activities which will push the boundaries of critical thought and demonstrate to students the importance of mathematical problems in Number & Operations, Geometry, Measurement, Data Analysis & Probability and Algebra using real world situations.

  15. Oriented strand board: new material for building construction

    International Nuclear Information System (INIS)

    Paridah Md Tahir; Ong, L.L.

    2001-01-01

    The paper will attempt to show the suitability and competitiveness of oriented strand board (OSB) in building construction. One important factor underlining the success of this product is the availability of the wood raw material. Plantation timbers such as rubberwood, paraserianthes falcataria, acacia crassicarpa, A. auriculiformis and A. mangium have been identified as the major source of this industry. We will focus on the domestic market as well as export market especially on the Asia Pacific region

  16. The relation between electroencephalogram asymmetry and attention biases to threat at baseline and under stress

    OpenAIRE

    Pérez-Edgar, Koraly; Kujawa, Autumn; Nelson, S. Katherine; Cole, Claire; Zapp, Daniel J.

    2013-01-01

    Electroencephalogram (EEG) asymmetry in the alpha frequency band has been implicated in emotion processing and broad approach-withdrawal motivation systems. Questions remain regarding the cognitive mechanisms that may help elucidate the observed links between EEG asymmetry and patterns of socioemotional functioning. The current study observed frontal EEG asymmetry patterns at rest and under social threat among young adults (N=45, M=21.1 years). Asymmetries were, in turn, associated with perfo...

  17. An optimal method of moments to measure the charge asymmetry at the Z0

    International Nuclear Information System (INIS)

    Bruemmer, N.C.

    1994-02-01

    Parity violation at LEP or SLC can be measured through the charge asymmetry. An optimal method of moments is developed here to measure this asymmetry, as well as similar asymmetries. This method is equivalent to the likelihood fit. It is simpler in use, as it gives analytical formulas for both the asymmetry and its statistical error. These formulas give the dependence of the accuracy on the experimental angular acceptance explicitly. (orig.)

  18. Formation of double-strand breaks in DNA of γ-irradiated bacteria depending on the function of fast repair processes of DNA single-strand breaks

    International Nuclear Information System (INIS)

    Petrov, S.I.; Gaziev, A.I.

    1980-01-01

    The formation of double-strand breaks in DNA of γ-irradiated ( 60 Co)Ex coli bacteria depending on the function of fast repair processes of DNA single-strand breaks, is investigated. The profiles of sedimentation of DNA Ex coli cells, irradiated at 0-2 deg C in the salt medium and in EDTA-borate buffer, are presented. It is shown that when irradiating cells in EDTA-borate buffer, the output of single- and double strand breaks in DNA is much higher than in the case of their irradiation in the minimum salt medium. The dependence of output of single-strand and double-strand breaks depending on the radiatier doze of E coli cells in the salt medium and EDTA-borate buffer, is studied. The supposition is made on the presence of a regulative interaction between the accumulation of DNA single-breaks and their repair with the formation of double-strand breaks. The functionating of fast and superfast repair processes considerably affects the formation of double-strand breaks in DNA of a bacterium cell. A considerable amount of double-breaks registered immediately after irradiation forms due to a close position of single-strand breaks on the opposite DNA strands

  19. Programmable autonomous synthesis of single-stranded DNA

    Science.gov (United States)

    Kishi, Jocelyn Y.; Schaus, Thomas E.; Gopalkrishnan, Nikhil; Xuan, Feng; Yin, Peng

    2018-02-01

    DNA performs diverse functional roles in biology, nanotechnology and biotechnology, but current methods for autonomously synthesizing arbitrary single-stranded DNA are limited. Here, we introduce the concept of primer exchange reaction (PER) cascades, which grow nascent single-stranded DNA with user-specified sequences following prescribed reaction pathways. PER synthesis happens in a programmable, autonomous, in situ and environmentally responsive fashion, providing a platform for engineering molecular circuits and devices with a wide range of sensing, monitoring, recording, signal-processing and actuation capabilities. We experimentally demonstrate a nanodevice that transduces the detection of a trigger RNA into the production of a DNAzyme that degrades an independent RNA substrate, a signal amplifier that conditionally synthesizes long fluorescent strands only in the presence of a particular RNA signal, molecular computing circuits that evaluate logic (AND, OR, NOT) combinations of RNA inputs, and a temporal molecular event recorder that records in the PER transcript the order in which distinct RNA inputs are sequentially detected.

  20. Paul Strand y las paradojas de la modernidad americana

    Directory of Open Access Journals (Sweden)

    Vicente Sánchez Biosca

    2010-06-01

    Full Text Available As contribuições de Strand para o cinema estão estreitamente relacionadas com seus trabalhos fotográficos da época e mesmo com um olhar que, apesar de suas múltiplas diferenças, possui muitos pontos em comum. Se em Manhatta (1920, Strand (em colaboração com Sheeler oferece uma síntese da natureza e da modernidade, em Redes (1934 o que predomina, em contrapartida, é a experiência da arte muralista mexicana e a influência de Eisenstein (em suas andanças por México são os fatores que determinam seus esforços na construção de uma épica dos operários. Mas sem dúvida, o projeto mais ambicioso de Strand (ao mando da produtora Frontier Films foi Native Land, o filme que atendeu às demandas do American Popular Front e as moldou nas palavras dos fundadores da pátria americana.

  1. Commercial possibilities for stranded conventional gas from Alaska's North Slope

    Science.gov (United States)

    Attanasi, E.D.; Freeman, P.A.

    2014-01-01

    Stranded gas resources are defined for this study as gas resources in discrete accumulations that are not currently commercially producible, or producible at full potential, for either physical or economic reasons. Approximately 35 trillion cubic feet (TCF) of stranded gas was identified on Alaska’s North Slope. The commercialization of this resource requires facilities to transport gas to markets where sales revenue will be sufficient to offset the cost of constructing and operating a gas delivery system. With the advent of the shale gas revolution, plans for a gas pipeline to the conterminous US have been shelved (at least temporarily) and the State and resource owners are considering a liquefied natural gas (LNG) export project that targets Asian markets. This paper focuses on competitive conditions for Asian gas import markets by estimating delivered costs of competing supplies from central Asia, Russia, Indonesia, Malaysia, and Australia in the context of a range of import gas demand projections for the period from 2020 to 2040. These suppliers’ costs are based on the cost of developing, producing, and delivering to markets tranches of the nearly 600 TCF of recoverable gas from their own conventional stranded gas fields. The results of these analyses imply that Alaska’s gas exports to Asia will likely encounter substantial competitive challenges. The sustainability of Asia’s oil-indexed LNG pricing is also discussed in light of a potentially intense level of competition.

  2. Communication Apprehension and Resting Alpha Range Asymmetry in the Anterior Cortex

    Science.gov (United States)

    Beatty, Michael J.; Heisel, Alan D.; Lewis, Robert J.; Pence, Michelle E.; Reinhart, Amber; Tian, Yan

    2011-01-01

    In this study, we examined the relationship between trait-like communication apprehension (CA) and resting alpha range asymmetry in the anterior cortex (AC). Although theory and research in cognitive neuroscience suggest that asymmetry in the AC constitutes a relatively stable, inborn, substrate of emotion, some studies indicate that asymmetry can…

  3. A Statistical Model of Head Asymmetry in Infants with Deformational Plagiocephaly

    DEFF Research Database (Denmark)

    Lanche, Stéphanie; Darvann, Tron Andre; Ólafsdóttir, Hildur

    2007-01-01

    Deformational plagiocephaly is a term describing cranial asymmetry and deformation commonly seen in infants. The purpose of this work was to develop a methodology for assessment and modelling of head asymmetry. The clinical population consisted of 38 infants for whom 3-dimensional surface scans...... quantitative description of the asymmetry present in the dataset....

  4. Collins and Sivers asymmetries for pions and kaons in muon-deuteron DIS

    Czech Academy of Sciences Publication Activity Database

    Alekseev, M.; Alexakhin, V. Yu.; Alexandrov, Yu.; Alexeev, G. D.; Amoroso, A.; Arbuzov, A.; Badelek, B.; Balestra, F.; Ball, J.; Barth, J.; Baum, G.; Bedfer, Y.; Bernet, C.; Bertini, R.; Bettinelli, M.; Birsa, R.; Bisplinghoff, J.; Bordalo, P.; Bradamante, F.; Bravar, A.; Bressan, A.; Brona, G.; Burtin, E.; Bussa, M.; Chapiro, A.; Chiosso, M.; Cicuttin, A.; Colantoni, M.; Costa, S.; Crespo, M.; Dalla Torre, S.; Dafni, T.; Das, S.; Dasgupta, S. S.; De Masi, R.; Dedek, N.; Denisov, O.; Dhara, L.; Diaz, V.; Dinkelbach, A.; Donskov, S.; Dorofeev, V.; Doshita, N.; Duic, V.; Dünnweber, W.; Efremov, A.V.; Eversheim, P.; Eyrich, W.; Faessler, M.; Falaleev, V.; Ferrero, A.; Ferrero, L.; Finger, M.; Finger jr., M.; Fischer, H.; Franco, C.; Franz, J.; Friedrich, J.; Frolov, V.; Garfagnini, R.; Gautheron, F.; Gavrichtchouk, O.; Gazda, R.; Gerassimov, S.; Geyer, R.; Giorgi, M.; Gobbo, B.; Goertz, S.; Gorin, A.; Grabmüller, S.; Grajek, O.; Grasso, A.; Grube, B.; Gushterski, R.; Guskov, A.; Haas, F.; Hannappel, J.; von Harrach, D.; Hasegawa, T.; Heckmann, J.; Hedicke, S.; Heinsius, F.; Hermann, R.; Hess, C.; Hinterberger, F.; von Hodenberg, M.; Horikawa, N.; Horikawa, S.; d'Hose, N.; Ilgner, C.; Ioukaev, A.; Ishimoto, S.; Ivanov, O.; Ivanshin, Yu.; Iwata, T.; Jahn, R.; Janata, A.; Jasinski, P.; Joosten, R.; Jouravlev, N. I.; Kabuss, E.; Kang, D.; Ketzer, B.; Khaustov, G.; Khokhlov, Y.; Kisselev, Y.; Klein, F.; Klimaszewski, K.; Koblitz, S.; Koivuniemi, J.; Kolosov, V.; Komissarov, E.; Kondo, K.; Königsmann, K.; Konorov, I.; Konstantinov, V.; Korentchenko, A.; Korzenev, A.; Kotzinian, A.; Koutchinski, N.; Kouznetsov, O.; Kral, A.; Kravchuk, N.; Kroumchtein, Z.; Kuhn, R.; Kunne, F.; Kurek, K.; Ladygin, M.; Lamanna, M.; Le Goff, J.; Lednev, A.; Lehmann, A.; Levorato, S.; Lichtenstadt, J.; Liska, T.; Ludwig, I.; Maggiora, A.; Maggiora, M.; Magnon, A.; Mallot, G.; Mann, A.; Marchand, C.; Marroncle, J.; Martin, A.; Marzec, J.; Massmann, F.; Matsuda, T.; Maximov, A.; Meyer, W.; Mielech, A.; Mikhailov, Y.; Moinester, M.; Mutter, A.; Nagaytsev, A.; Nagel, T.; Nähle, O.; Nassalski, J.; Neliba, S.; Nerling, F.; Neubert, S.; Neyret, D.; Nikolaenko, V.; Nikolaev, K.; Olshevsky, A.; Ostrick, M.; Padee, A.; Pagano, P.; Panebianco, S.; Panknin, R.; Panzieri, D.; Paul, S.; Pawlukiewicz-Kaminska, B.; Pesaro, G.; Peshekhonov, D.; Peshekhonov, V.; Piragino, G.; Platchkov, S.; Pochodzalla, J.; Polak, J.; Polyakov, V.; Pretz, J.; Procureur, S.; Quintans, C.; Rajotte, J.; Ramos, S.; Rapatsky, V.; Reicherz, G.; Reggiani, D.; Richter, A.; Robinet, F.; Rocco, E.; Rondio, E.; Rozhdestvensky, A.; Ryabchikov, D.; Samoylenko, V.; Sandacz, A.; Santos, H.; Sapozhnikov, M.; Sarkar, S.; Savin, I.; Sbrizzai, G.; Schiavon, P.; Schill, C.; Schmitt, L.; Schönmeier, P.; Schröder, W.; Shevchenko, O.; Siebert, H.; Silva, L.; Sinha, L.; Sissakian, A.; Slunecka, M.; Smirnov, G.; Sosio, S.; Sozzi, F.; Srnka, Aleš; Stinzing, F.; Stolarski, M.; Sugonyaev, V.; Sulc, M.; Sulej, R.; Tchalishev, V.; Tessaro, S.; Tessarotto, F.; Teufel, A.; Tkatchev, L.; Venugopal, G.; Virius, M.; Vlassov, N.; Vossen, A.; Webb, R.; Weise, E.; Weitzel, Q.; Windmolders, R.; Wirth, S.; Wislicki, W.; Wollny, H.; Zaremba, K.; Zavertyaev, M.; Zemlyanichkina, E.; Zhao, J.; Ziegler, R.; Zvyagin, A.

    2009-01-01

    Roč. 673, č. 2 (2009), s. 127-135 ISSN 0370-2693 R&D Projects: GA MŠk ME 492 Institutional research plan: CEZ:AV0Z20650511 Keywords : deuteron * transverse single-spin asymmetry * identified hadrons * Collins asymmetry * Sivers asymmetry Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 5.083, year: 2009

  5. Observation of strong azimuthal asymmetry between slow and fast particles from high energy nuclear collisions

    International Nuclear Information System (INIS)

    Gustafsson, H.A.; Gutbrod, H.H.; Kolb, B.; Loehner, H.; Ludewigt, B.; Poskanzer, A.M.; Renner, T.; Riedesel, H.; Ritter, H.G.; Siemiarczuk, T.; Stepaniak, J.; Warwick, A.; Wieman, H.

    1984-10-01

    Evidence is presented for the strong azimuthal asymmetry between slow and fast fragments in nuclear collisions in the energy interval of 0.4 to 1 GeV per nucleon. The asymmetry gets stronger when incident energy and impact parameter decrease. The results on the A dependence of the azimuthal asymmetry are also presented. (orig.)

  6. Sub-ensemble monitoring of DNA strand displacement using multiparameter single-molecule FRET

    OpenAIRE

    Baltierra Jasso, Laura; Morten, Michael; Magennis, Steven William

    2018-01-01

    Non-enzymatic DNA strand displacement is an important mechanism in dynamic DNA nanotechnology. Here we show that the large parameter space that is accessible by single-molecule FRET is ideal for the simultaneous monitoring of multiple reactants and products of DNA strand exchange reactions. We monitored the strand displacement from double-stranded DNA (dsDNA) by single-stranded DNA (ssDNA) at 37 °C; the data were modelled as a second-order reaction approaching equilibrium, with a rate constan...

  7. In vitro Assays for Eukaryotic Leading/Lagging Strand DNA Replication.

    Science.gov (United States)

    Schauer, Grant; Finkelstein, Jeff; O'Donnell, Mike

    2017-09-20

    The eukaryotic replisome is a multiprotein complex that duplicates DNA. The replisome is sculpted to couple continuous leading strand synthesis with discontinuous lagging strand synthesis, primarily carried out by DNA polymerases ε and δ, respectively, along with helicases, polymerase α-primase, DNA sliding clamps, clamp loaders and many other proteins. We have previously established the mechanisms by which the polymerases ε and δ are targeted to their 'correct' strands, as well as quality control mechanisms that evict polymerases when they associate with an 'incorrect' strand. Here, we provide a practical guide to differentially assay leading and lagging strand replication in vitro using pure proteins.

  8. Metallographic investigation of fracture behavior in ITER-style Nb$_{3}$Sn superconducting strands

    CERN Document Server

    Jewell, M C; Larbalestier, D C; Nijhuis, A

    2009-01-01

    In this work we specify the extent to which fracture in two ITER-style Nb$_{3}$Sn composite strands occurs in a collective or individual manner, under mechanical tension and bending from the TARSIS apparatus at the University of Twente. A bronze-route strand from European Advanced Superconductors (EAS), which has very uniform, well-spaced filaments, has a widely distributed (200 μm) fracture field and exhibits a composite of individual and collective cracks. An internal tin strand from Oxford Instruments – Superconducting Technology (OST) demonstrates much more localized, collective fracture behavior. The filaments in this strand are about four times larger (in area) than the filaments in the EAS strand, and also agglomerate significantly during heat treatment upon conversion of the Nb to Nb$_{3}$Sn. These results demonstrate that the architecture of the strand can play a significant role in determining the mechanical toughness of the composite, and that strand design should incorporate mechanical consider...

  9. Digitizing the moving face: asymmetries of emotion and gender

    Directory of Open Access Journals (Sweden)

    Ashish Desai

    2009-04-01

    Full Text Available In a previous study with dextral males, Richardson and Bowers (1999 digitized real time video signals and found movement asymmetries over the left lower face for emotional, but not non-emotional expressions. These findings correspond to observations, based on subjective ratings of static pictures, that the left side of the face is more intensely expressive than the right (Sackeim, 1978. From a neuropsychological perspective, one possible interpretation of these findings is that emotional priming of the right hemisphere of the brain results in more muscular activity over the contralateral left than ipsilateral right side of the lower face. The purpose of the present study was to use computer-imaging methodology to determine whether there were gender differences in movement asymmetries across the face. We hypothesized that females would show less evidence of facial movement asymmetries during the expression of emotion. This hypothesis was based on findings of gender differences in the degree to which specific cognitive functions may be lateralized in the brain (i.e., females less lateralized than males. Forty-eight normal dextral college students (25 females, 23 males were videotaped while they displayed voluntary emotional expressions. A quantitative measure of movement change (called entropy was computed by subtracting the values of corresponding pixel intensities between adjacent frames and summing their differences. The upper and lower hemiface regions were examined separately due to differences in the cortical enervation of facial muscles in the upper (bilateral versus lower face (contralateral. Repeated measures ANOVA’s were used to analyze for the amount of overall facial movement and for facial asymmetries. Certain emotions were associated with significantly greater overall facial movement than others (p fear > (angry =sad > neutral. Both males and females showed this same pattern, with no gender differences in the total amount of facial

  10. Aging effects on cerebral asymmetry: a voxel-based morphometry and diffusion tensor imaging study.

    Science.gov (United States)

    Takao, Hidemasa; Abe, Osamu; Yamasue, Hidenori; Aoki, Shigeki; Kasai, Kiyoto; Sasaki, Hiroki; Ohtomo, Kuni

    2010-01-01

    The hemispheres of the human brain are functionally and structurally asymmetric. The purpose of this study was to evaluate the effects of aging on gray and white matter asymmetry. Two hundred twenty-six right-handed normal volunteers aged 21-71 years were included in this study. The effects of aging on gray matter volume asymmetry and white matter fractional anisotropy asymmetry were evaluated with use of voxel-based morphometry and voxel-based analysis of fractional anisotropy maps derived from diffusion tensor imaging (DTI), respectively. The voxel-based morphometry showed no significant correlation between age and gray matter volume asymmetry. The voxel-based analysis of DTI also showed no significant correlation between age and white matter fractional anisotropy asymmetry. Our results showed no significant effects of aging on either gray matter volume asymmetry or white matter fractional anisotropy asymmetry.

  11. Normal formation and repair of γ-radiation-induced single and double strand DNA breaks in Down syndrome fibroblasts

    International Nuclear Information System (INIS)

    Steiner, M.E.; Woods, W.G.

    1982-01-01

    Fibroblasts from patients with Down syndrome (Trisomy 21) were examined for repair capability of γ-radiation-induced single strand and double strand DNA breaks. Formation and repair of DNA breaks were determined by DNA alkaline and non-denaturing elution techniques. Down syndrome fibroblasts were found to repair single strand and double strand breaks as well as fibroblasts from normal controls. (orig.)

  12. Double Spin Asymmetries, ALL, for Di-hadrons in PHENIX

    Science.gov (United States)

    McKinney, Cameron

    2010-11-01

    The Relativistic Heavy Ion Collider (RHIC), through its polarized proton-proton collisions, provides leading order access to δG, the gluon contribution to the proton spin. Previous measurements have shown δG(x) dx to be consistent with zero in the Bjorken-x range of 0.05 to 0.2, whereas there is presently no measurement constraining δG (x) for x below or above this range. The Muon Piston Calorimeter provides the opportunity to expand the constrained range by allowing measurements of double spin asymmetries for azimuthally-separated pairs of 0̂'s at forward rapidity, 3.1<=|η|<=3.9, for √s=200 GeV and 500 GeV data taken in 2009. We present PYTHIA simulations studying the kinematics and possible asymmetries from di-hadron production at RHIC.

  13. Beam spin asymmetry in deep and exclusive pi0 electroproduction

    International Nuclear Information System (INIS)

    R. De Masi

    2007-01-01

    The beam spin asymmetry (BSA) in the exclusive reaction ep->ep pi0 was measured with the CEBAF 5.77 GeV polarized electron beam and Large Acceptance Spectrometer(CLAS). The xB, Q2, t and phi dependences of the pi0 BSA are presented in the deep inelastic regime. The asymmetries are fitted with a sin(phi) function and their amplitudes are extracted. Overall, they are of the order of 0.04 - 0.11 and roughly independent of t. This is the signature of a non-zero longitudinal-transverse interference. The implications concerning the applicability of a formalism based on generalized parton distributions, as well as the extension of a Regge formalism at high photon virtualities, are discussed

  14. Spin asymmetries for elastic scattering in krypton at intermediate energies

    International Nuclear Information System (INIS)

    Went, M R; McEachran, R P; Lohmann, Birgit; MacGillivray, W R

    2002-01-01

    Measurements of the spin asymmetry for elastic scattering of spin-polarized electrons from krypton are presented, for incident energies in the range 20-200 eV. The measured spin asymmetries are generally small, and do not exceed 0.25 in magnitude at any energy or angle. The experimental results are compared with calculated values of the Sherman function, obtained by solution of the Dirac-Fock equations. The calculations have been performed with the inclusion of polarization and dynamic distortion potentials, and with the addition of an absorption potential to model inelastic processes. For incident energies of 50, 60 and 65 eV, the calculated values of the Sherman function are shown to be extremely sensitive to the details of the model, with the addition of the absorption potential producing dramatically different results

  15. Hemispherical power asymmetry from scale-dependent modulated reheating

    International Nuclear Information System (INIS)

    McDonald, John

    2013-01-01

    We propose a new model for the hemispherical power asymmetry of the CMB based on modulated reheating. Non-Gaussianity from modulated reheating can be small enough to satisfy the bound from Planck if the dominant modulation of the inflaton decay rate is linear in the modulating field σ. σ must then acquire a spatially-modulated power spectrum with a red scale-dependence. This can be achieved if the primordial perturbation of σ is generated via tachyonic growth of a complex scalar field. Modulated reheating due to σ then produces a spatially modulated and scale-dependent sub-dominant contribution to the adiabatic density perturbation. We show that it is possible to account for the observed asymmetry while remaining consistent with bounds from quasar number counts, non-Gaussianity and the CMB temperature quadupole. The model predicts that the adiabatic perturbation spectral index and its running will be modified by the modulated reheating component

  16. Hemispheric asymmetry of liking for representational and abstract paintings.

    Science.gov (United States)

    Nadal, Marcos; Schiavi, Susanna; Cattaneo, Zaira

    2017-10-13

    Although the neural correlates of the appreciation of aesthetic qualities have been the target of much research in the past decade, few experiments have explored the hemispheric asymmetries in underlying processes. In this study, we used a divided visual field paradigm to test for hemispheric asymmetries in men and women's preference for abstract and representational artworks. Both male and female participants liked representational paintings more when presented in the right visual field, whereas preference for abstract paintings was unaffected by presentation hemifield. We hypothesize that this result reflects a facilitation of the sort of visual processes relevant to laypeople's liking for art-specifically, local processing of highly informative object features-when artworks are presented in the right visual field, given the left hemisphere's advantage in processing such features.

  17. Tau lepton charge asymmetry and new physics at the LHC

    International Nuclear Information System (INIS)

    Gupta, Sudhir Kumar; Valencia, German

    2011-01-01

    We consider the possibility of studying new physics that singles out the tau lepton at the LHC. We concentrate on the tau lepton charge asymmetry in τ + τ - pair production as a tool to probe this physics beyond the standard model. We consider two generic scenarios for the new physics. We first study a nonuniversal Z' boson as an example of a new resonance that can single out tau leptons. We then consider vector lepto-quarks coupling the first-generation quarks with the third-generation leptons as an example of nonresonant new physics. We find that in both cases the charge asymmetry can be sufficiently sensitive to the new physics to provide useful constraints at the LHC.

  18. ASYMMETRY OF THE BRAIN AT ADAPTATION TO HYPOXIA

    Directory of Open Access Journals (Sweden)

    V. I. Portnichenko

    2012-11-01

    Full Text Available Association between cerebral blood flow and higher nervous activity in people at different stages of adaptation to the midlands was studied. Investigation were performed before, during and after a three-week stay in the mountains at an altitude of 2100 m, as well as during short-term ups without the physical load on the height of 3900 m. In the initial period of adaptation to hypoxia desynchronization between the nerve processes in the cerebral cortex and brain blood flow was observed. There was an inversion and an increase in the asymmetry of cerebral blood flow in the direction of the dominance of the left hemisphere of the brain. After the three-week stay in the mountains asymmetry of cerebral blood flow was disappeared, blood flow to the brain was reduced, hemispheric symmetry was formed, and blood flow synchronized with the nerve processes in the cerebral cortex again was restored.

  19. Two-dimensional chiral asymmetry in unidirectional magnetic anisotropy structures

    Directory of Open Access Journals (Sweden)

    P. Perna

    2016-05-01

    Full Text Available We investigate the symmetry-breaking effects of magnetic nanostructures that present unidirectional (one-fold magnetic anisotropy. Angular and field dependent transport and magnetic properties have been studied in two different exchange-biased systems, i.e. ferromagnetic (FM/ antiferromagnetic (AFM bilayer and spin-valve structures. We experimentally show the direct relationships between the magnetoresistance (MR response and the magnetization reversal pathways for any field value and direction. We demonstrate that even though the MR signals are related to different transport phenomena, namely anisotropic magnetoresistance (AMR and giant magnetoresistance (GMR, chiral asymmetries are found around the magnetization hard-axis direction, in both cases originated from the one-fold symmetry of the interfacial exchange coupling. Our results indicate that the chiral asymmetry of transport and magnetic behaviors are intrinsic of systems with an unidirectional contribution.

  20. Matter-antimatter asymmetry induced by a running vacuum coupling

    Energy Technology Data Exchange (ETDEWEB)

    Lima, J.A.S. [Universidade de Sao Paulo, Departamento de Astronomia, Sao Paulo (Brazil); Singleton, D. [California State University Fresno, Department of Physics, Fresno, CA (United States); Institute of Experimental and Theoretical Physics Al-Farabi KazNU, Almaty (Kazakhstan)

    2017-12-15

    We show that a CP-violating interaction induced by a derivative coupling between the running vacuum and a non-conserving baryon current may dynamically break CPT and trigger baryogenesis through an effective chemical potential. By assuming a non-singular class of running vacuum cosmologies which provides a complete cosmic history (from an early inflationary de Sitter stage to the present day quasi-de Sitter acceleration), it is found that an acceptable baryon asymmetry is generated for many different choices of the model parameters. It is interesting that the same ingredient (running vacuum energy density) addresses several open cosmological questions/problems: avoids the initial singularity, provides a smooth exit for primordial inflation, alleviates both the coincidence and the cosmological constant problems, and, finally, is also capable of explaining the generation of matter-antimatter asymmetry in the very early Universe. (orig.)

  1. Double spin asymmetry in exclusive $\\rho^0$ muoproduction at COMPASS

    CERN Document Server

    Alexakhin, V Yu; Alexandrov, Yu A; Alexeev, G D; Amoroso, A; Arbuzov, A; Badelek, B; Balestra, F; Ball, J; Baum, G; Barth, J; Bedfer, Y; Bernet, C; Bertini, R; Bettinelli, M; Birsa, R; Bisplinghoff, J; Bordalo, P; Bradamante, Franco; Bravar, A; Bressan, A; Brona, G; Burtin, E; Bussa, M P; Chapiro, A; Chiosso, M; Cicuttin, A; Colantoni, M L; Costa, S; Crespo, M L; D'Hose, N; Dalla Torre, S; Das, S; Das-Gupta, S S; De Masi, R; Dedek, N; Denisov, O Yu; Dhara, L; Díaz, V; Dinkelbach, A M; Donskov, S V; Dorofeev, V A; Doshita, N; Duic, V; Dünnweber, W; Eversheim, P D; Eyrich, W; Fabro, M; Faessler, M; Falaleev, V; Ferrero, A; Ferrero, L; Finger, M; Finger, M Jr; Fischer, H; Franco, C; Franz, J; Friedrich, J M; Frolov, V; Garfagnini, R; Gautheron, F; Gavrichtchouk, O P; Gazda, R; Gerassimov, S G; Geyer, R; Giorgi, M; Gobbo, B; Görtz, S; Gorin, A M; Grabmuller, S; Grajek, O A; Grasso, A; Grube, B; Gushterski, R; Guskov, A; Haas, F; Hannappel, J; Von Harrach, D; Hasegawa, T; Heckmann, J; Hedicke, S; Heinsius, F H; Hermann, R; Hess, C; Hinterberger, F; Von Hodenberg, M; Horikawa, N; Horikawa, S; Ilgner, C; Ioukaev, A I; Ishimoto, S; Ivanov, O; Ivanshin, Yu; Iwata, T; Jahn, R; Janata, A; Jasinski, P; Joosten, R; Jouravlev, N I; Kabuss, E M; Kang, D; Ketzer, B; Khaustov, G V; Khokhlov, Yu A; Kisselev, Yu; Klein, F; Klimaszewski, K; Koblitz, S; Koivuniemi, J H; Kolosov, V N; Komissarov, E V; Kondo, K; Knigsmann, K; Konorov, I; Konstantinov, V F; Korentchenko, A S; Korzenev, A; Kotzinian, A M; Koutchinski, N A; Kuznetsov, O; Kravchuk, N P; Kral, A; Kroumchtein, Z V; Kühn, R; Kunne, Fabienne; Kurek, K; Ladygin, M E; Lamanna, M; Le Goff, J M; Lednev, A A; Lehmann, A; Lichtenstadt, J; Liska, T; Ludwig, I; Maggiora, A; Maggiora, M; Magnon, A; Mallot, G K; Mann, A; Marchand, C; Marroncle, J; Martin, A; Marzec, J; Massmann, F; Matsuda, T; Maksimov, A N; Meyer, W; Mielech, A; Mikhailov, Yu V; Moinester, M A; Mutter, A; Nahle, O; Nagaytsev, A; Nagel, T; Nassalski, J P; Neliba, S; Nerling, F; Neubert, a S; Neyret, D P; Nikolaenko, V I; Nikolaev, K; Olshevskii, A G; Ostrick, M; Padee, A; Pagano, P; Panebianco, S; Panknin, R; Panzieri, D; Paul, S; Pawlukiewicz-Kaminska, B; Peshekhonov, V D; Piragino, G; Platchkov, S; Pochodzalla, J; Polak, J; Polyakov, V A; Pretz, J; Procureur, S; Quintans, C; Rajotte, J F; Rapatsky, V; Ramos, S; Reicherz, G; Richter, A; Robinet, F; Rocco, E; Rondio, E; Rozhdestvensky, A M; Ryabchikov, D I; Samoylenko, V D; Sandacz, A; Santos, H; Sapozhnikov, M G; Sarkar, S; Savin, I A; Schiavon, Paolo; Schill, C; Schmitt, L; Schonmeier, P; Schroder, W; Shevchenko, O Yu; Siebert, H W; Silva, L; Sinha, L; Sissakian, A N; Slunecka, M; Smirnov, G I; Sosio, S; Sozzi, F; Sugonyaev, V P; Srnka, A; Stinzing, F; Stolarski, M; Sulc, M; Sulej, R; Takabayashi, N; Tchalishev, V V; Tessaro, S; Tessarotto, F; Teufel, A; Tkatchev, L G; Venugopal, G; Virius, M; Vlassov, N V; Vossen, A; Webb, R; Weise, E; Weitzel, Q; Windmolders, R; Wirth, S; Wilicki, W; Zaremba, s K; Zavertyaev, M; Zemlyanichkina, E; Zhao, J; Ziegler, R; Zvyagin, A

    2007-01-01

    The longitudinal double spin asymmetry A_1^rho for exclusive leptoproduction of rho^0 mesons, mu + N -> mu + N + rho, is studied using the COMPASS 2002 and 2003 data. The measured reaction is incoherent exclusive rho^0 production on polarised deuterons. The Q^2 and x dependence of A_1^rho is presented in a wide kinematical range: 3x10^-3 < Q^2 < 7 (GeV/c)^2 and 5x10^-5 < x < 0.05. The presented results are the first measurements of A_1^rho at small Q2 (Q2 < 0.1 (GeV/c)^2) and small x (x < 3x10^-3). The asymmetry is in general compatible with zero in the whole kinematical range.

  2. Top forward-backward asymmetry with general Z' couplings

    International Nuclear Information System (INIS)

    Duraisamy, Murugeswaran; Datta, Alakabha; Rashed, Ahmed

    2011-01-01

    The measurement of the top forward-backward asymmetry in tt production measured at the Tevatron shows deviation from the standard model prediction. A u→t transition via a flavor-changing Z ' can explain the data. We show that left-handed t L u L Z ' couplings can be constrained from B d,s mixing while the constrains on the right-handed couplings t R u R Z ' vanish in the limit of m u →0. We then consider the most general form of the tuZ ' interaction which includes vector-axial vector as well as tensor type couplings and study how these couplings affect the top forward-backward asymmetry.

  3. Two-dimensional chiral asymmetry in unidirectional magnetic anisotropy structures

    Energy Technology Data Exchange (ETDEWEB)

    Perna, P., E-mail: paolo.perna@imdea.org; Guerrero, R.; Niño, M. A. [IMDEA-Nanoscience, c/ Faraday, 9 Campus de Cantoblanco, 28049 Madrid (Spain); Ajejas, F.; Maccariello, D.; Cuñado, J. L. [IMDEA-Nanoscience, c/ Faraday, 9 Campus de Cantoblanco, 28049 Madrid (Spain); DFMC and Instituto “Nicolás Cabrera”, Universidad Autónoma de Madrid, 28049 Madrid (Spain); Muñoz, M. [IMM-CSIC, Isaac Newton 8, PTM, 28760 Tres Cantos, Madrid (Spain); ISOM, Universidad Politécnica de Madrid, 28040 Madrid (Spain); Prieto, J. L. [ISOM, Universidad Politécnica de Madrid, 28040 Madrid (Spain); Miranda, R.; Camarero, J. [IMDEA-Nanoscience, c/ Faraday, 9 Campus de Cantoblanco, 28049 Madrid (Spain); DFMC and Instituto “Nicolás Cabrera”, Universidad Autónoma de Madrid, 28049 Madrid (Spain); Condensed Matter Physics Center (IFIMAC), Universidad Autónoma de Madrid, 28049 Madrid (Spain)

    2016-05-15

    We investigate the symmetry-breaking effects of magnetic nanostructures that present unidirectional (one-fold) magnetic anisotropy. Angular and field dependent transport and magnetic properties have been studied in two different exchange-biased systems, i.e. ferromagnetic (FM)/ antiferromagnetic (AFM) bilayer and spin-valve structures. We experimentally show the direct relationships between the magnetoresistance (MR) response and the magnetization reversal pathways for any field value and direction. We demonstrate that even though the MR signals are related to different transport phenomena, namely anisotropic magnetoresistance (AMR) and giant magnetoresistance (GMR), chiral asymmetries are found around the magnetization hard-axis direction, in both cases originated from the one-fold symmetry of the interfacial exchange coupling. Our results indicate that the chiral asymmetry of transport and magnetic behaviors are intrinsic of systems with an unidirectional contribution.

  4. Synchro-betatron resonance due to gap voltage asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Baartman, R

    1992-11-01

    RF cavities for synchrotrons are not in general axially symmetric. This can be due, for example, to the location of the input power coupling loop. It can cause the voltage on one side of the accelerating gap to be different from that on the other side. Associated with this asymmetry is an rf magnetic field which deflects a beam particle by an amount depending upon its rf phase. The deflection can accumulate if the betatron tune is situated on a synchrotron sideband of the integer resonance. We develop the theory for this resonance and apply it to the KAON Factory Booster and to the SSC LEB. We find that the upper limit on allowable voltage asymmetry across the beam pipe is 0.1% in both cases. (author) 5 refs., 1 tab.

  5. Study of interhemispheric asymmetries in electroencephalographic signals by frequency analysis

    International Nuclear Information System (INIS)

    Zapata, J F; Garzon, J

    2011-01-01

    This study provides a new method for the detection of interhemispheric asymmetries in patients with continuous video-electroencephalography (EEG) monitoring at Intensive Care Unit (ICU), using wavelet energy. We obtained the registration of EEG signals in 42 patients with different pathologies, and then we proceeded to perform signal processing using the Matlab program, we compared the abnormalities recorded in the report by the neurophysiologist, the images of each patient and the result of signals analysis with the Discrete Wavelet Transform (DWT). Conclusions: there exists correspondence between the abnormalities found in the processing of the signal with the clinical reports of findings in patients; according to previous conclusion, the methodology used can be a useful tool for diagnosis and early quantitative detection of interhemispheric asymmetries.

  6. A search asymmetry reversed by figure-ground assignment.

    Science.gov (United States)

    Humphreys, G W; Müller, H

    2000-05-01

    We report evidence demonstrating that a search asymmetry favoring concave over convex targets can be reversed by altering the figure-ground assignment of edges in shapes. Visual search for a concave target among convex distractors is faster than search for a convex target among concave distractors (a search asymmetry). By using shapes with ambiguous local figure-ground relations, we demonstrated that search can be efficient (with search slopes around 10 ms/item) or inefficient (with search slopes around 30-40 ms/item) with the same stimuli, depending on whether edges are assigned to concave or convex "figures." This assignment process can operate in a top-down manner, according to the task set. The results suggest that attention is allocated to spatial regions following the computation of figure-ground relations in parallel across the elements present. This computation can also be modulated by top-down processes.

  7. Asymmetry and irregularity border as discrimination factor between melanocytic lesions

    Science.gov (United States)

    Sbrissa, David; Pratavieira, Sebastião.; Salvio, Ana Gabriela; Kurachi, Cristina; Bagnato, Vanderlei Salvadori; Costa, Luciano Da Fontoura; Travieso, Gonzalo

    2015-06-01

    Image processing tools have been widely used in systems supporting medical diagnosis. The use of mobile devices for the diagnosis of melanoma can assist doctors and improve their diagnosis of a melanocytic lesion. This study proposes a method of image analysis for melanoma discrimination from other types of melanocytic lesions, such as regular and atypical nevi. The process is based on extracting features related with asymmetry and border irregularity. It were collected 104 images, from medical database of two years. The images were obtained with standard digital cameras without lighting and scale control. Metrics relating to the characteristics of shape, asymmetry and curvature of the contour were extracted from segmented images. Linear Discriminant Analysis was performed for dimensionality reduction and data visualization. Segmentation results showed good efficiency in the process, with approximately 88:5% accuracy. Validation results presents sensibility and specificity 85% and 70% for melanoma detection, respectively.

  8. Cold fission description with constant and varying mass asymmetries

    International Nuclear Information System (INIS)

    Duarte, S.B.; Rodriguez, O.; Tavares, O.A.P.; Goncalves, M.; Garcia, F.; Guzman, F.

    1998-01-01

    Different description for varying the mass asymmetry in the fragmentation process are used to calculate the cold fission barrier penetrability. The relevance of the appropriate choice for both the description of the pre-scission phase and inertia coefficient to unify alpha decay, cluster radioactivity, and spontaneous cold fission processes in the same theoretical framework is explicitly shown. We calculate the half-life of all possible partition modes of nuclei of A > 200 following the most recent Mass Table by Audi and Wapstra. It is shown that if one uses the description in which the mass asymmetry is maintained constant during the fragmentation process, the experimental half-life-values and mass yield of 234 U cold fission are satisfactorily reproduced. (author)

  9. Cosmic microwave background power asymmetry from non-Gaussian modulation.

    Science.gov (United States)

    Schmidt, Fabian; Hui, Lam

    2013-01-04

    Non-Gaussianity in the inflationary perturbations can couple observable scales to modes of much longer wavelength (even superhorizon), leaving as a signature a large-angle modulation of the observed cosmic microwave background power spectrum. This provides an alternative origin for a power asymmetry that is otherwise often ascribed to a breaking of statistical isotropy. The non-Gaussian modulation effect can be significant even for typical ~10(-5) perturbations while respecting current constraints on non-Gaussianity if the squeezed limit of the bispectrum is sufficiently infrared divergent. Just such a strongly infrared-divergent bispectrum has been claimed for inflation models with a non-Bunch-Davies initial state, for instance. Upper limits on the observed cosmic microwave background power asymmetry place stringent constraints on the duration of inflation in such models.

  10. Lepton asymmetry, neutrino spectral distortions, and big bang nucleosynthesis

    Science.gov (United States)

    Grohs, E.; Fuller, George M.; Kishimoto, C. T.; Paris, Mark W.

    2017-03-01

    We calculate Boltzmann neutrino energy transport with self-consistently coupled nuclear reactions through the weak-decoupling-nucleosynthesis epoch in an early universe with significant lepton numbers. We find that the presence of lepton asymmetry enhances processes which give rise to nonthermal neutrino spectral distortions. Our results reveal how asymmetries in energy and entropy density uniquely evolve for different transport processes and neutrino flavors. The enhanced distortions in the neutrino spectra alter the expected big bang nucleosynthesis light element abundance yields relative to those in the standard Fermi-Dirac neutrino distribution cases. These yields, sensitive to the shapes of the neutrino energy spectra, are also sensitive to the phasing of the growth of distortions and entropy flow with time/scale factor. We analyze these issues and speculate on new sensitivity limits of deuterium and helium to lepton number.

  11. High mass-asymmetry distributions of fissioning nuclei

    International Nuclear Information System (INIS)

    Sandulescu, A.; Lusting, H.J.; Hahn, J.; Greiner, W.

    1978-07-01

    It is shown that new mass-asymmetry valleys are appearing in the fragmentation potential V(l,eta) as function of the length l and mass-asymmetry coordinate eta = (A 1 - A 2 )to a correct treatment of the shell effects such that for separated fragments the shell effects equal the sum of the shell effects of the individual fragments and correspond to the double magic fragments 48 Ca, 78 Ni, 132 Sn and 208 Pb or may be 56 Ni. Also is shown that the fission mass-distributions have additional peaks corresponding to the bottom of these new valleys. The calculations are illustrated for 252 No and 238 U. The preliminary results show for 238 U relatively high percent yields in agreement with present available experimental data. (author)

  12. Time symmetry and asymmetry in quantum mechanics and quantum cosmology

    International Nuclear Information System (INIS)

    Gell-Mann, M.; Hartle, J.B.

    1992-01-01

    The disparity between the time symmetry of the fundamental laws of physics and the time asymmetries of the observed universe has been a subject of fascination for physicists since the late 19th century. It was also for Sakharov, if the authors judge correctly from his writings the following general time asymmetries are observed in this universe: The thermodynamic arrow of time --- the fact that approximately isolated systems are now almost all evolving towards equilibrium in the same direction of time. The psychological arrow of time --- we remember the past, we predict the future. The arrow of time of retarded electromagnetic radiation. The arrow of time supplied by the CP non-invariance of the weak interactions and the CPT invariance of field theory. The arrow of time of the approximately uniform expansion of the universe. The arrow of time supplied by the growth of inhomogeneity in the expanding universe

  13. Asymmetries: a fuzzy topic in the process of integration

    Directory of Open Access Journals (Sweden)

    Jaime Alberto Rendón Acevedo

    2012-12-01

    Full Text Available FTAs have gained prominence in the trade policy of Latin American countries to the detriment of other forms of economic integration. In this trend there is a predominance of south-north schemes, where all kinds of asymmetries are evident. The aim of this paper is to demonstrate that the reduction of asymmetries should be a primary goal of the FTAs. The methodology is a review of literature on Latin American FTAs with the United States, particularly those signed by Mexico, Chile and Colombia. As a result, we see that an appropriate treatment of the differences between involved economies is not only desirable for the development of Latin American countries but also it is possible through monetary and industrial policy adjusted to the reality of these countries.

  14. SANE Of Jefferson Lab: Spin Asymmetries on the Nucleon Experiment

    International Nuclear Information System (INIS)

    Ahmidouch, Abdellah

    2011-01-01

    The Spin Asymmetry on the Nucleon Experiment (SANE) at Jefferson Lab measures proton spin observables A 1 p , A 2 p and structure functions g 1 p and g 2 p over a broad range of Bjorken scaling variable x from 0.3 to 0.8, for four-momentum transfers ranging from 2.5 GeV 2 to 6.5 GeV 2 . Inclusive double spin asymmetries were measured by scattering 4.7 and 5.9-GeV longitudinally polarized electron beam off a polarized solid NH 3 target, in both parallel and near-perpendicular configuration. Scattered electrons were detected using a novel non-magnetic detector array with 194-msr acceptance. This paper presents the physics motivation for the experiment, the detector performance, and the latest status of the ongoing data analysis.

  15. Asymmetry effects of supersymmetric QCD in dilepton production

    International Nuclear Information System (INIS)

    Contogouris, A.P.; Tanaka, H.

    1985-01-01

    A Callan-Gross-type relation between the structure functions determining dilepton production, which is satisfied by the basic O(1) and O(α/sub s/) subprocesses of conventional QCD, is investigated in supersymmetric QCD (SQCD). It is found that SQCD subprocesses, mainly due to the presence of scalar quarks, strongly violate this relation, thus leading to sizable asymmetry effects in the angular distribution of dileptons. As an illustration, calculations are carried for p-barp→l + l - +X at CERN collider and Fermilab Tevatron energies (√s = 540 and 1600 GeV, respectively) and for pp→l + l - +X at Tevatron energy; with scalar quarks of mass 20 GeV and light gluinos, asymmetries in the range of 20%--5% are found. The significance of the effects as a test of the short-distance structure of SQCD (valence part of the scalar-quark distribution) is discussed

  16. Longitudinal Target-Spin Asymmetries for Deeply Virtual Compton Scattering

    Science.gov (United States)

    Seder, E.; Biselli, A.; Pisano, S.; Niccolai, S.; Smith, G. D.; Joo, K.; Adhikari, K.; Amaryan, M. J.; Anderson, M. D.; Anefalos Pereira, S.; Avakian, H.; Battaglieri, M.; Bedlinskiy, I.; Bono, J.; Boiarinov, S.; Bosted, P.; Briscoe, W.; Brock, J.; Brooks, W. K.; Bültmann, S.; Burkert, V. D.; Carman, D. S.; Carlin, C.; Celentano, A.; Chandavar, S.; Charles, G.; Colaneri, L.; Cole, P. L.; Contalbrigo, M.; Crabb, D.; Crede, V.; D'Angelo, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Deur, A.; Djalali, C.; Doughty, D.; Dupre, R.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fegan, S.; Filippi, A.; Fleming, J. A.; Fradi, A.; Garillon, B.; Garçon, M.; Gevorgyan, N.; Ghandilyan, Y.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gohn, W.; Gothe, R. W.; Griffioen, K. A.; Guegan, B.; Guidal, M.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Harrison, N.; Hattawy, M.; Hirlinger Saylor, N.; Holtrop, M.; Hughes, S. M.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Jo, H. S.; Joosten, S.; Keith, C. D.; Keller, D.; Khachatryan, G.; Khandaker, M.; Kim, A.; Kim, W.; Klein, A.; Klein, F. J.; Koirala, S.; Kubarovsky, V.; Kuhn, S. E.; Lenisa, P.; Livingston, K.; Lu, H. Y.; MacGregor, I. J. D.; Markov, N.; Mayer, M.; McKinnon, B.; Meekins, D. G.; Mineeva, T.; Mirazita, M.; Mokeev, V.; Montgomery, R.; Moody, C. I.; Moutarde, H.; Movsisyan, A.; Munoz Camacho, C.; Nadel-Turonski, P.; Niculescu, I.; Osipenko, M.; Ostrovidov, A. I.; Paolone, M.; Pappalardo, L. L.; Park, K.; Park, S.; Pasyuk, E.; Peng, P.; Phelps, W.; Pogorelko, O.; Price, J. W.; Prok, Y.; Protopopescu, D.; Puckett, A. J. R.; Ripani, M.; Rizzo, A.; Rosner, G.; Rossi, P.; Roy, P.; Sabatié, F.; Salgado, C.; Schott, D.; Schumacher, R. A.; Senderovich, I.; Simonyan, A.; Skorodumina, I.; Sokhan, D.; Sparveris, N.; Stepanyan, S.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Sytnik, V.; Taiuti, M.; Tang, W.; Tian, Y.; Ungaro, M.; Voskanyan, H.; Voutier, E.; Walford, N. K.; Watts, D. P.; Wei, X.; Weinstein, L. B.; Wood, M. H.; Zachariou, N.; Zana, L.; Zhang, J.; Zonta, I.; CLAS Collaboration

    2015-01-01

    A measurement of the electroproduction of photons off protons in the deeply inelastic regime was performed at Jefferson Lab using a nearly 6 GeV electron beam, a longitudinally polarized proton target, and the CEBAF Large Acceptance Spectrometer. Target-spin asymmetries for e p →e'p'γ events, which arise from the interference of the deeply virtual Compton scattering and the Bethe-Heitler processes, were extracted over the widest kinematics in Q2 , xB, t , and ϕ , for 166 four-dimensional bins. In the framework of generalized parton distributions, at leading twist the t dependence of these asymmetries provides insight into the spatial distribution of the axial charge of the proton, which appears to be concentrated in its center. These results also bring important and necessary constraints for the existing parametrizations of chiral-even generalized parton distributions.

  17. Current topics in DNA double-strand break repair

    International Nuclear Information System (INIS)

    Kobayashi, Junya; Takata, Minoru; Iwabuchi, Kuniyoshi; Miyagawa, Kiyoshi; Sonoda, Eiichiro; Suzuki, Keiji; Tauchi, Hiroshi

    2008-01-01

    DNA double strand break (DSB) is one of the most critical types of damage which is induced by ionizing radiation. In this review, we summarize current progress in investigations on the function of DSB repair-related proteins. We focused on recent findings in the analysis of the function of proteins such as 53BP1, histone H2AX, Mus81-Eme1, Fanc complex, and UBC13, which are found to be related to homologous recombination repair or to non-homologous end joining. In addition to the function of these proteins in DSB repair, the biological function of nuclear foci formation following DSB induction is discussed. (author)

  18. PROTOCOL FOR GAS SAMPLING AND ANALYSIS IN STRANDED MARINE MAMMALS

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Yara Bernaldo de Quirós, Óscar González-Díaz, Manuel Arbelo, Marisa Andrada & Antonio Fernández ### Abstract Gas sampling in stranded marine mammals can now be performed in situ using the appropriate vacuum tubes, insulin syringes and an aspirometer. Glass vacuum tubes are used for extraction of gas from cavities such as the intestine, pterigoyd air sacs, pneumothorax or subcapsular emphysema as well as for storage of the gas sample at room temperature and pressure. Insulin s...

  19. Offshore Earthquakes Do Not Influence Marine Mammal Stranding Risk on the Washington and Oregon Coasts

    Science.gov (United States)

    Grant, Rachel A.; Savirina, Anna

    2018-01-01

    Simple Summary Marine mammals stranding on coastal beaches is not unusual. However, there appears to be no single cause for this, with several causes being probable, such as starvation, contact with humans (for example boat strike or entanglement with fishing gear), disease, and parasitism. We evaluated marine mammal stranding off the Washington and Oregon coasts and looked at offshore earthquakes as a possible contributing factor. Our analysis showed that offshore earthquakes did not make marine mammals more likely to strand. We also analysed a subset of data from the north of Washington State and found that non-adult animals made up a large proportion of stranded animals, and for dead animals the commonest cause of death was disease, traumatic injury, or starvation. Abstract The causes of marine mammals stranding on coastal beaches are not well understood, but may relate to topography, currents, wind, water temperature, disease, toxic algal blooms, and anthropogenic activity. Offshore earthquakes are a source of intense sound and disturbance and could be a contributing factor to stranding probability. We tested the hypothesis that the probability of marine mammal stranding events on the coasts of Washington and Oregon, USA is increased by the occurrence of offshore earthquakes in the nearby Cascadia subduction zone. The analysis carried out here indicated that earthquakes are at most, a very minor predictor of either single, or large (six or more animals) stranding events, at least for the study period and location. We also tested whether earthquakes inhibit stranding and again, there was no link. Although we did not find a substantial association of earthquakes with strandings in this study, it is likely that there are many factors influencing stranding of marine mammals and a single cause is unlikely to be responsible. Analysis of a subset of data for which detailed descriptions were available showed that most live stranded animals were pups, calves, or

  20. Mechanical behaviors of multi-filament twist superconducting strand under tensile and cyclic loading

    Science.gov (United States)

    Wang, Xu; Li, Yingxu; Gao, Yuanwen

    2016-01-01

    The superconducting strand, serving as the basic unit cell of the cable-in-conduit-conductors (CICCs), is a typical multi-filament twist composite which is always subjected to a cyclic loading under the operating condition. Meanwhile, the superconducting material Nb3Sn in the strand is sensitive to strain frequently relating to the performance degradation of the superconductivity. Therefore, a comprehensive study on the mechanical behavior of the strand helps understanding the superconducting performance of the strained Nb3Sn strands. To address this issue, taking the LMI (internal tin) strand as an example, a three-dimensional structural finite element model, named as the Multi-filament twist model, of the strand with the real configuration of the LMI strand is built to study the influences of the plasticity of the component materials, the twist of the filament bundle, the initial thermal residual stress and the breakage and its evolution of the filaments on the mechanical behaviors of the strand. The effective properties of superconducting filament bundle with random filament breakage and its evolution versus strain are obtained based on the damage theory of fiber-reinforced composite materials proposed by Curtin and Zhou. From the calculation results of this model, we find that the occurrence of the hysteresis loop in the cyclic loading curve is determined by the reverse yielding of the elastic-plastic materials in the strand. Both the initial thermal residual stress in the strand and the pitch length of the filaments have significant impacts on the axial and hysteretic behaviors of the strand. The damage of the filaments also affects the axial mechanical behavior of the strand remarkably at large axial strain. The critical current of the strand is calculated by the scaling law with the results of the Multi-filament twist model. The predicted results of the Multi-filament twist model show an acceptable agreement with the experiment.

  1. Higher 5-hydroxymethylcytosine identifies immortal DNA strand chromosomes in asymmetrically self-renewing distributed stem cells.

    Science.gov (United States)

    Huh, Yang Hoon; Cohen, Justin; Sherley, James L

    2013-10-15

    Immortal strands are the targeted chromosomal DNA strands of nonrandom sister chromatid segregation, a mitotic chromosome segregation pattern unique to asymmetrically self-renewing distributed stem cells (DSCs). By nonrandom segregation, immortal DNA strands become the oldest DNA strands in asymmetrically self-renewing DSCs. Nonrandom segregation of immortal DNA strands may limit DSC mutagenesis, preserve DSC fate, and contribute to DSC aging. The mechanisms responsible for specification and maintenance of immortal DNA strands are unknown. To discover clues to these mechanisms, we investigated the 5-methylcytosine and 5-hydroxymethylcytosine (5hmC) content on chromosomes in mouse hair follicle DSCs during nonrandom segregation. Although 5-methylcytosine content did not differ significantly, the relative content of 5hmC was significantly higher in chromosomes containing immortal DNA strands than in opposed mitotic chromosomes containing younger mortal DNA strands. The difference in relative 5hmC content was caused by the loss of 5hmC from mortal chromosomes. These findings implicate higher 5hmC as a specific molecular determinant of immortal DNA strand chromosomes. Because 5hmC is an intermediate during DNA demethylation, we propose a ten-eleven translocase enzyme mechanism for both the specification and maintenance of nonrandomly segregated immortal DNA strands. The proposed mechanism reveals a means by which DSCs "know" the generational age of immortal DNA strands. The mechanism is supported by molecular expression data and accounts for the selection of newly replicated DNA strands when nonrandom segregation is initiated. These mechanistic insights also provide a possible basis for another characteristic property of immortal DNA strands, their guanine ribonucleotide dependency.

  2. Molecular investigation of evaporation of biodroplets containing single-strand DNA on graphene surface.

    Science.gov (United States)

    Akbari, Fahimeh; Foroutan, Masumeh

    2018-02-14

    In this study, the water droplet behaviour of four different types of single-strand DNA with homogeneous base sequence on a graphene substrate during evaporation of the droplet was investigated using molecular dynamics (MD) simulation. The simulation results indicated that the evaporation depended on the DNA sequence. The observed changes can be divided into four parts: (i) vaporization mode, (ii) evaporation flux, (iii) mechanism of single-strand placement on the surface, and (iv) consideration of remaining single strands after evaporation. Our simulation observations indicated different evaporation modes for thymine biodroplets as compared to those for other biodroplets. The evaporation of the thymine biodroplets occurred with an increase in the contact angle, while that of the other biodroplets occur in a constant contact angle mode. Moreover, thymine biodroplets generate the lowest contact line compared to other single strands, and it is always placed far away from the centre of the droplets during evaporation. Investigating variations in the evaporation flux shows that thymine has the highest evaporation flux and guanine has the lowest. Moreover, during initial evaporation, the flux of evaporation increases at the triple point of the biodroplets containing thymine single strands, while it decreases in the other biodroplets. The following observation was obtained from the study of the placement of single strands on the substrate: guanine and thymine interacted slower than other single strands during evaporation with graphene, adenine single strand had a higher folding during evaporation, and guanine single strand showed the lowest end-to-end distance. The investigation of single-strand DNA after evaporation shows that adenine produces the most stable structure at the end of evaporation. In addition, cytosine is the most stretched single-strand DNA due to its lack of internal π-π stacking and hydrogen bonding. Therefore, cytosine single strand is more

  3. Comunication: the Paradigms of symmetry, antisymmetry anda asymmetry

    OpenAIRE

    Winfried Nöth

    2011-01-01

    The paper examines how the process of communication is represented (a) in the etymology of the conceptof communication, (b) in everyday metaphors of communication, and (c) in 20th century theories andmodels of communication. These reflect this paradox in three different scenarios: the paradigms ofsymmetry, antisymmetry and asymmetry. The dead end into which communication theory is led by theproponents of the latter paradigm is contrasted with some solutions offered by Charles S. Peirce’scommu...

  4. ASYMMETRY OF MARKET RETURNS AND THE MEAN VARIANCE FRONTIER

    OpenAIRE

    SENGUPTA, Jati K.; PARK, Hyung S.

    1994-01-01

    The hypothesis that the skewness and asymmetry have no significant impact on the mean variance frontier is found to be strongly violated by monthly U.S. data over the period January 1965 through December 1974. This result raises serious doubts whether the common market portifolios such as SP 500, value weighted and equal weighted returns can serve as suitable proxies for meanvariance efficient portfolios in the CAPM framework. A new test for assessing the impact of skewness on the variance fr...

  5. Asymmetry in ecosystem responses to precipitation: Theory, observation and experimentation

    Science.gov (United States)

    Sala, O.; Gherardi, L.; Reichmann, L.; Peters, D.

    2017-12-01

    Ecosystem processes such as primary production respond to changes in precipitation that occur annually and at longer time scales. The questions guiding this presentation are whether ecosystem responses to wet and dry years are symmetrical. Is the increase in productivity in a wet year similar in absolute value to the decrease in productivity in a dry year following a wet year? Is the response to one dry or wet year similar tot response of several consecutive wet and dry years? Do all plant-functional groups respond in a similar way to changes in precipitation? To address the questions we explore the theory behind a potential asymmetry and report on experimental results. Analysis of the cost and benefits of plant responses to changes in precipitation support the idea asymmetrical responses because the threshold for abscising organs that have already been deployed should be higher than the threshold to deploy new organs. However, experiments in a desert grassland in New Mexico where we experimentally increased and decreased precipitation from one year to the next showed that the response was symmetrical. Another mechanism that may yield asymmetries is the productivity response to changes in precipitation is associated with the shape of the relationship between precipitation and productivity. Straight-line relationship may yield no asymmetries whereas a saturating or concave up relationship may result in different asymmetries. Here, we report results from an experiment that yielded concave down responses for grasses and concave up for shrubs. Finally, we report results from a 10-year experiment showing asymmetric responses of grasses and shrubs. Moreover, the magnitude of the sign of the responses changed with the time since the beginning of the precipitation manipulation.

  6. Modification of Otolith Reflex Asymmetries Following Space Flight

    Science.gov (United States)

    Clarke, Andrew H.; Schoenfeld, Uwe; Wood, Scott J.

    2011-01-01

    We hypothesize that changes in otolith-mediated reflexes adapted for microgravity contribute to perceptual, gaze and postural disturbances upon return to Earth s gravity. Our goal was to determine pre- versus post-fight differences in unilateral otolith reflexes that reflect these adaptive changes. This study represents the first comprehensive examination of unilateral otolith function following space flight. Ten astronauts participated in unilateral otolith function tests three times pre-flight and up to four times after Shuttle flights from landing day through the subsequent 10 days. During unilateral centrifugation (UC, +/- 3.5cm at 400deg/s), utricular function was examined by the perceptual changes reflected by the subjective visual vertical (SVV) and by video-oculographic measurement of the otolith-mediated ocular counter-roll (OOR). Unilateral saccular reflexes were recorded by measurement of collic Vestibular Evoked Myogenic Potential (cVEMP). Although data from a few subjects were not obtained early post-flight, a general increase in asymmetry of otolith responses was observed on landing day relative to pre-flight baseline, with a subsequent reversal in asymmetry within 2-3 days. Recovery to baseline levels was achieved within 10 days. This fluctuation in the asymmetry measures appeared strongest for SVV, in a consistent direction for OOR, and in an opposite direction for cVEMP. These results are consistent with our hypothesis that space flight results in adaptive changes in central nervous system processing of otolith input. Adaptation to microgravity may reveal asymmetries in otolith function upon to return to Earth that were not detected prior to the flight due to compensatory mechanisms.

  7. Discrete ambiguities in CP-violating asymmetries in B decays

    International Nuclear Information System (INIS)

    London, David

    1998-01-01

    The CP-angles α, β and γ can be extracted from CP-violating asymmetries in the B system, but only up to discrete ambiguities. These discrete ambiguities make it difficult to determine with certainty whether or not new physics is present. I show that, if the condition α+β+γ=π is imposed, there remains a twofold ambiguity in the CP-angle set (α,β,γ), and I discuss ways to cleanly resolve this final discrete ambiguity

  8. Manual asymmetries in bimanual isochronous tapping tasks in children.

    Science.gov (United States)

    Faria, Inês; Diniz, Ana; Barreiros, João

    2017-01-01

    Tapping tasks have been investigated throughout the years, with variations in features such as the complexity of the task, the use of one or both hands, the employ of auditory or visual stimuli, and the characteristics of the subjects. The evaluation of lateral asymmetries in tapping tasks in children offers an insight into the structure of rhythmic movements and handedness at early stages of development. The current study aims to investigate the ability of children (aged six and seven years-old) to maintain a rhythm, in a bimanual tapping task at two different target frequencies, as well as the manual asymmetries displayed while doing so. The analyzed data in this work are the series of the time intervals between successive taps. We suggest several profiles of behavior, regarding the overall performance of children in both tempo conditions. We also propose a new method of quantifying the variability of the performance and the asymmetry of the hands, based on ellipses placed on scatter plots of the non-dominant-dominant series versus the dominant-non-dominant series. We then use running correlations to identify changes of coordination tendencies over time. The main results show that variability is larger in the task with the longer target interval. Furthermore, most children evidence lateral asymmetries, but in general they show the capacity to maintain the mean of consecutive intertap intervals of both hands close to the target interval. Finally, we try to interpret our findings in the light of existing models and timing modes. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Prospects for time-dependent asymmetries at LHCb

    CERN Document Server

    INSPIRE-00260500

    2012-01-01

    LHCb is already providing leading measurements of time-dependent CP asymmetries with 1 fb$^{-1}$ of data. With the LHCb detector, and further one with the LHCb upgrade, very high-precision time-dependent CP measurements are expected to stringently test the CKM paradigm and to the search for possible small NP effects. A review of the current precision and the prospects for these time-dependent quantities with the LHCb and LHCb upgraded detectors are summarised in this paper.

  10. Asymmetry within social groups: division of labour and intergroup competition.

    Science.gov (United States)

    Barker, J L; Loope, K J; Reeve, H K

    2016-03-01

    Social animals vary in their ability to compete with group members over shared resources and also vary in their cooperative efforts to produce these resources. Competition among groups can promote within-group cooperation, but many existing models of intergroup cooperation do not explicitly account for observations that group members invest differentially in cooperation and that there are often within-group competitive or power asymmetries. We present a game theoretic model of intergroup competition that investigates how such asymmetries affect within-group cooperation. In this model, group members adopt one of two roles, with relative competitive efficiency and the number of individuals varying between roles. Players in each role make simultaneous, coevolving decisions. The model predicts that although intergroup competition increases cooperative contributions to group resources by both roles, contributions are predominantly from individuals in the less competitively efficient role, whereas individuals in the more competitively efficient role generally gain the larger share of these resources. When asymmetry in relative competitive efficiency is greater, a group's per capita cooperation (averaged across both roles) is higher, due to increased cooperation from the competitively inferior individuals. For extreme asymmetry in relative competitive efficiency, per capita cooperation is highest in groups with a single competitively superior individual and many competitively inferior individuals, because the latter acquiesce and invest in cooperation rather than within-group competition. These predictions are consistent with observed features of many societies, such as monogynous Hymenoptera with many workers and caste dimorphism. © 2015 The Authors. Journal of Evolutionary Biology published by John Wiley & Sons Ltd on behalf of European Society for Evolutionary Biology.

  11. Single spin asymmetries in semi-inclusive deep inelastic scattering

    International Nuclear Information System (INIS)

    Mulders, P.J.

    1998-01-01

    In this talk I want to illustrate the many possibilities for studying the structure of hadrons in hard scattering processes by giving a number of examples involving increasing complexity in the demands for particle polarization, particle identification or polarimetry. In particular the single spin asymmetries will be discussed. The measurements discussed in this talk are restricted to lepton-hadron scattering, but can be found in various other hard processes such as Drell-Yan scattering or e + e - annihilation. (author)

  12. The Asymmetry and Modularity of the Hyoid Bone

    OpenAIRE

    Urbanová, Petra; Hejna, Petr; Zátopková, Lenka; Safr, Miroslav

    2014-01-01

    Morphological variation is a result of interplay among multiple intervening factors. For hyoid bones, the shape and size differences have been scarcely covered in the literature and in majority limited to studies of sexual dimorphism or age dependency. To our knowledge, the human hyoid bone, in complete opposite to other cranial bones, has not been fully utilized to address development questions in terms of asymmetry or modularity. In the present paper, we used landmark-based methods of geome...

  13. LEP asymmetries and fits of the standard model

    International Nuclear Information System (INIS)

    Pietrzyk, B.

    1994-01-01

    The lepton and quark asymmetries measured at LEP are presented. The results of the Standard Model fits to the electroweak data presented at this conference are given. The top mass obtained from the fit to the LEP data is 172 -14-20 +13+18 GeV; it is 177 -11-19 +11+18 when also the collider, ν and A LR data are included. (author). 10 refs., 3 figs., 2 tabs

  14. Asymmetry in development (mineralisation of permanent mandibular canine roots

    Directory of Open Access Journals (Sweden)

    Burić Mirjana V.

    2012-01-01

    Full Text Available Introduction. The development of the teeth is closely associated with the proper and unobstructed physical and psychological development of the child. Aim. To determine the existence of asymmetry in the development of the roots of the lower permanent canine teeth in different age groups of children of both sexes. Material and methods. The study was conducted on 523 ortopantomograms (253 boys and 270 girls of orthodontic patients aged 6 to 14 years of the Dental Clinic in Niš. We analyzed the development of asymmetry in the lower permanent canine root, using the method of Gleiser and Hunt, or the modification by Tijanić (1981. Results. It was found that asymmetry in the development of the root in both sexes of the lower canine teeth was present in 20 patients (3.82%, 10 boys (3.95% and 10 girls (3.70%. The difference is in the range of one stage. Asymmetric development of the roots of the lower incisors in girls and boys usually present in the 7th and 8th stages (60% in girls and in 50% in boys. In 90% of girls in developing asymmetry the root of the lower canine is present in a single stage, and in 10% of girls it presents within three stages. Asymmetric development of the root of the lower canine is the most common in the 7th and 8th stages of development (55%. Conclusion. Asymmetric root development of permanent lower canines was found in 3.82% of patients. More than half of respondents (55% had asymmetrical canine root development stage in half and three quarters of the total root length. The results of this study indicate that the canine is the tooth with very little variations in its development.

  15. Measurements of the B0 bar B0 CP asymmetry

    International Nuclear Information System (INIS)

    Lueth, V.

    1993-01-01

    A figure of merit for a measurement of CP violation is the error on the intrinsic asymmetry A CP . The observed asymmetry A obs will always be smaller than A CP due to a number of effects that dilute the measurement. If one defines A obs =DA CP , where D represents the product of all dilution factors, then the error on A CP , δA CP is related to the number of produced B 0 or bar B 0 , N prod , needed to obtain a given error on δA CP by N prod =1/((δA CP ) 2 D 2 εBr). To determine the figure of merit for a particular decay mode one must determine the number of reconstructed events N obs and calculate the corresponding dilution factor D. N obs depends on the luminosity and production cross section, on the branching ratio of the B 0 or bar B 0 into the specific final state under study, Br, and on ε, the reconstruction efficiency for both the combination of the signal CP state and any tagging signal. The production rate N prod , the dilution factor D, and the efficiency ε, differ substantially in magnitude as a function of energy and detector layout. The detection efficiency and dilution factor can both be written as a product of several factors that can be estimated for a particular experiment. These factors depend critically on the decay mode under study, the tagging method, the detector configuration, and more generally on the production process, backgrounds, and detector performance. Furthermore, the present knowledge of these quantities varies largely, as well as ones ability to ultimately measure the dilution factor which relates the experimentally observed asymmetry to the true CP asymmetry

  16. Poloidal asymmetries of flows in the Tore Supra tokamak

    Science.gov (United States)

    Vermare, L.; Hennequin, P.; Gürcan, Ö. D.; Garbet, X.; Honoré, C.; Clairet, F.; Giacalone, J. C.; Morel, P.; Storelli, A.; Tore Supra Team

    2018-02-01

    Simultaneous measurements of binormal velocity of density fluctuations using two separate Doppler backscattering systems at the low field side and at the top of the plasma show significant poloidal asymmetry. The measurements are performed in the core region between the radii 0.7 Supra tokamak. A possible generation mechanism by the ballooned structure of the underlying turbulence, in the form of convective cells, is proposed for explaining the observation of these poloidally asymmetric mean flows.

  17. Asymmetry of Anticipatory Postural Adjustment During Gait Initiation

    OpenAIRE

    Hiraoka, Koichi; Hatanaka, Ryota; Nikaido, Yasutaka; Jono, Yasutomo; Nomura, Yoshifumi; Tani, Keisuke; Chujo, Yuta

    2014-01-01

    The purpose of this study was to investigate the asymmetry of anticipatory postural adjustment (APA) during gait initiation and to determine whether the process of choosing the initial swing leg affects APA during gait initiation. The participants initiated gait with the leg indicated by a start tone or initiated gait with the leg spontaneously chosen. The dependent variables of APA were not significantly different among the condition of initiating gait with the preferred leg indicated by the...

  18. Asymmetry features for classification of thermograms in breast cancer detection

    Science.gov (United States)

    Nowak, Robert M.; Okuniewski, Rafał; Oleszkiewicz, Witold; Cichosz, Paweł; Jagodziński, Dariusz; Matysiewicz, Mateusz; Neumann, Łukasz

    2016-09-01

    The computer system for an automatic interpretation of thermographic pictures created by the Br-aster devices uses image processing and machine learning algorithms. The huge set of attributes analyzed by this software includes the asymmetry measurements between corresponding images, and these features are analyzed in presented paper. The system was tested on real data and achieves accuracy comparable to other popular techniques used for breast tumour detection.

  19. Gluon asymmetries in the leptoproduction of J/Ψ

    International Nuclear Information System (INIS)

    Godbole, R.M.; Gupta, S.; Sridhar, K.

    1990-07-01

    We study J/Ψ production, in deep inelastic scattering experiments with polarised beams and polarised targets. The spin asymmetries are seen to depend strongly on the particular form of the spin dependent gluon distributions used. Therefore, it should be possible in these experiments, to discriminate between different parametrizations of polarised gluon distributions, and hence between the distinctly different physical pictures of the proton spin underlying these parametrizations. (author). 18 refs, 4 figs, 1 tab

  20. Evaluation of asymmetry collimator for a new generation telecobalt machine

    International Nuclear Information System (INIS)

    Suliman, E.E.

    2008-01-01

    A new model of the telecobalt unit, theratron equinox-100, (MDS Nordion, Canada) equipped with a single 60 degree motorized wedge (MW) and upper (X) and lower (Y) asymmetric jaws have been evaluated. Symmetrical jaws were commissioned in pinnacle 3 (Philips), the 3D treatment planning system (TPS). The profiles and central axis depth dose (CADD) were measured with wellhofer blue water phantom for various field sizes using 0.13 cc thimble ionization chamber (Scanditronix wellhofer, Uppsala, Sweden) and the data were commissioned in pinnacle 3 . These profiles and CADD for symmetry jaws were compared with asymmetry jaws for various field sizes. Also beam profiles for 5*5, 10*10 and 20*20 cm 2 for symmetry and asymmetry field sizes at 5 and 10 cm depths measured with 2D-array (two dimensional detector array with 729 vented ionization chambers with a size of 5*5 mm 2 , PTW, Germany), are compared. A homogeneous phantom generated in pinnacle 3 . The dose calculated in this phantom at 10 cm depth for various field sizes of symmetry and asymmetry jaws using collapse cone convolution (cc convolution) model with a grid size of 4 mm, and compared with measured dose in a water phantom at 10 cm depth with a 0.6 cc thimble ion chamber FC-65-G and DOSEI electrometer for field sizes of 5*5, 10*10 and 20*20 cm 2 using IAEA dosimetry protocol TRS-398. The variation of measured and calculated doses at 10 cm depth were within 1%. The asymmetry jaws were successfully commissioned in pinnacle 3 .(Author)

  1. Tidal Turbines’ Layout in a Stream with Asymmetry and Misalignment

    Directory of Open Access Journals (Sweden)

    Nicolas Guillou

    2017-11-01

    Full Text Available A refined assessment of tidal currents variability is a prerequisite for successful turbine deployment in the marine environment. However, the numerical evaluation of the tidal kinetic energy resource relies, most of the time, on integrated parameters, such as the averaged or maximum stream powers. Predictions from a high resolution three-dimensional model are exploited here to characterize the asymmetry and misalignment between the flood and ebb tidal currents in the “Raz de Sein”, a strait off western Brittany (France with strong potential for array development. A series of parameters is considered to assess resource variability and refine the cartography of local potential tidal stream energy sites. The strait is characterized by strong tidal flow divergence with currents’ asymmetry liable to vary output power by 60% over a tidal cycle. Pronounced misalignments over 20 ∘ are furthermore identified in a great part of energetic locations, and this may account for a deficit of the monthly averaged extractable energy by more than 12%. As sea space is limited for turbines, it is finally suggested to aggregate flood and ebb-dominant stream powers on both parts of the strait to output energy with reduced asymmetry.

  2. Gender differences in hemispheric asymmetry for face processing

    Directory of Open Access Journals (Sweden)

    Matarazzo Silvia

    2006-06-01

    Full Text Available Abstract Background Current cognitive neuroscience models predict a right-hemispheric dominance for face processing in humans. However, neuroimaging and electromagnetic data in the literature provide conflicting evidence of a right-sided brain asymmetry for decoding the structural properties of faces. The purpose of this study was to investigate whether this inconsistency might be due to gender differences in hemispheric asymmetry. Results In this study, event-related brain potentials (ERPs were recorded in 40 healthy, strictly right-handed individuals (20 women and 20 men while they observed infants' faces expressing a variety of emotions. Early face-sensitive P1 and N1 responses to neutral vs. affective expressions were measured over the occipital/temporal cortices, and the responses were analyzed according to viewer gender. Along with a strong right hemispheric dominance for men, the results showed a lack of asymmetry for face processing in the amplitude of the occipito-temporal N1 response in women to both neutral and affective faces. Conclusion Men showed an asymmetric functioning of visual cortex while decoding faces and expressions, whereas women showed a more bilateral functioning. These results indicate the importance of gender effects in the lateralization of the occipito-temporal response during the processing of face identity, structure, familiarity, or affective content.

  3. Baryon asymmetry of the Universe in the standard model

    International Nuclear Information System (INIS)

    Farrar, G.R.; Shaposhnikov, M.E.

    1994-01-01

    We study the interactions of quarks and antiquarks with the changing Higgs field during the electroweak phase transition, including quantum mechanical and some thermal effects, with the only source of CP violation being the known CKM phase. We show that the GIM cancellation, which has been commonly thought to imply a prediction which is at least 10 orders of magnitude too small, can be evaded in certain kinematic regimes, for instance, when the strange quark is totally reflected but the down quark is not. We report on a quantitative calculation of the asymmetry in a one-dimensional approximation based on the present understanding of the physics of the high-temperature environment, but with some aspects of the problem oversimplified. The resulting prediction for the magnitude and sign of the present baryonic asymmetry of the Universe agrees with the observed value, with moderately optimistic assumptions about the dynamics of the phase transition. Both magnitude and sign of the asymmetry have an intricate dependence on quark masses and mixings, so that quantitative agreement between prediction and observation would be highly nontrivial. At present uncertainties related to the dynamics of the EW phase transition and the oversimplifications of our treatment are too great to decide whether or not this is the correct explanation for the presence of remnant matter in our Universe; however, the present work makes it clear that the minimal standard model cannot be discounted as a contender for explaining this phenomenon

  4. Effect of cephalometer misalignment on calculations of facial asymmetry.

    Science.gov (United States)

    Lee, Ki-Heon; Hwang, Hyeon-Shik; Curry, Sean; Boyd, Robert L; Norris, Kevin; Baumrind, Sheldon

    2007-07-01

    In this study, we evaluated errors introduced into the interpretation of facial asymmetry on posteroanterior (PA) cephalograms due to malpositioning of the x-ray emitter focal spot. We tested the hypothesis that horizontal displacements of the emitter from its ideal position would produce systematic displacements of skull landmarks that could be fully accounted for by the rules of projective geometry alone. A representative dry skull with 22 metal markers was used to generate a series of PA images from different emitter positions by using a fully calibrated stereo cephalometer. Empirical measurements of the resulting cephalograms were compared with mathematical predictions based solely on geometric rules. The empirical measurements matched the mathematical predictions within the limits of measurement error (x= 0.23 mm), thus supporting the hypothesis. Based upon this finding, we generated a completely symmetrical mathematical skull and calculated the expected errors for focal spots of several different magnitudes. Quantitative data were computed for focal spot displacements of different magnitudes. Misalignment of the x-ray emitter focal spot introduces systematic errors into the interpretation of facial asymmetry on PA cephalograms. For misalignments of less than 20 mm, the effect is small in individual cases. However, misalignments as small as 10 mm can introduce spurious statistical findings of significant asymmetry when mean values for large groups of PA images are evaluated.

  5. Moral asymmetries in judgments of agency withstand ludicrous causal deviance

    Science.gov (United States)

    Sousa, Paulo; Holbrook, Colin; Swiney, Lauren

    2015-01-01

    Americans have been shown to attribute greater intentionality to immoral than to amoral actions in cases of causal deviance, that is, cases where a goal is satisfied in a way that deviates from initially planned means (e.g., a gunman wants to hit a target and his hand slips, but the bullet ricochets off a rock into the target). However, past research has yet to assess whether this asymmetry persists in cases of extreme causal deviance. Here, we manipulated the level of mild to extreme causal deviance of an immoral versus amoral act. The asymmetry in attributions of intentionality was observed at all but the most extreme level of causal deviance, and, as we hypothesized, was mediated by attributions of blame/credit and judgments of action performance. These findings are discussed as they support a multiple-concepts interpretation of the asymmetry, wherein blame renders a naïve concept of intentional action (the outcome matches the intention) more salient than a composite concept (the outcome matches the intention and was brought about by planned means), and in terms of their implications for cross-cultural research on judgments of agency. PMID:26441755

  6. Cell chirality: emergence of asymmetry from cell culture.

    Science.gov (United States)

    Wan, Leo Q; Chin, Amanda S; Worley, Kathryn E; Ray, Poulomi

    2016-12-19

    Increasing evidence suggests that intrinsic cell chirality significantly contributes to the left-right (LR) asymmetry in embryonic development, which is a well-conserved characteristic of living organisms. With animal embryos, several theories have been established, but there are still controversies regarding mechanisms associated with embryonic LR symmetry breaking and the formation of asymmetric internal organs. Recently, in vitro systems have been developed to determine cell chirality and to recapitulate multicellular chiral morphogenesis on a chip. These studies demonstrate that chirality is indeed a universal property of the cell that can be observed with well-controlled experiments such as micropatterning. In this paper, we discuss the possible benefits of these in vitro systems to research in LR asymmetry, categorize available platforms for single-cell chirality and multicellular chiral morphogenesis, and review mathematical models used for in vitro cell chirality and its applications in in vivo embryonic development. These recent developments enable the interrogation of the intracellular machinery in LR axis establishment and accelerate research in birth defects in laterality.This article is part of the themed issue 'Provocative questions in left-right asymmetry'. © 2016 The Author(s).

  7. A Matter of Degree: Strength of Brain Asymmetry and Behaviour

    Directory of Open Access Journals (Sweden)

    Lesley J. Rogers

    2017-04-01

    Full Text Available Research on a growing number of vertebrate species has shown that the left and right sides of the brain process information in different ways and that lateralized brain function is expressed in both specific and broad aspects of behaviour. This paper reviews the available evidence relating strength of lateralization to behavioural/cognitive performance. It begins by considering the relationship between limb preference and behaviour in humans and primates from the perspectives of direction and strength of lateralization. In birds, eye preference is used as a reflection of brain asymmetry and the strength of this asymmetry is associated with behaviour important for survival (e.g., visual discrimination of food from non-food and performance of two tasks in parallel. The same applies to studies on aquatic species, mainly fish but also tadpoles, in which strength of lateralization has been assessed as eye preferences or turning biases. Overall, the empirical evidence across vertebrate species points to the conclusion that stronger lateralization is advantageous in a wide range of contexts. Brief discussion of interhemispheric communication follows together with discussion of experiments that examined the effects of sectioning pathways connecting the left and right sides of the brain, or of preventing the development of these left-right connections. The conclusion reached is that degree of functional lateralization affects behaviour in quite similar ways across vertebrate species. Although the direction of lateralization is also important, in many situations strength of lateralization matters more. Finally, possible interactions between asymmetry in different sensory modalities is considered.

  8. Top quark asymmetry from a non-Abelian horizontal symmetry

    CERN Document Server

    Jung, Sunghoon; Wells, James D

    2011-01-01

    Motivated by the persistence of a large measured top quark forward-backward asymmetry at the Tevatron, we examine a model of non-Abelian flavor gauge symmetry. The exchange of the gauge bosons in the $t$-channel can give a large $\\Afb$ due to the forward Rutherford scattering peak. We address generic constraints on non-Abelian $t$-channel physics models including flavor diagonal resonances and potentially dangerous contributions to inclusive top pair cross sections. We caution on the general difficulty of comparing theoretical predictions for top quark signals to the existing experimental results due to potentially important acceptance effects. The first signature at the Large Hadron Collider can be a large inclusive top pair cross section, or like-sign dilepton events, although the latter signal is much smaller than in Abelian models. Deviations of the invariant mass distributions at the LHC will also be promising signatures. A more direct consistency check of the Tevatron asymmetry through the LHC asymmetry...

  9. Asymmetry in species regional dispersal ability and the neutral theory.

    Directory of Open Access Journals (Sweden)

    Jiajia Liu

    Full Text Available The neutral assumption that individuals of either the same or different species share exactly the same birth, death, migration, and speciation probabilities is fundamental yet controversial to the neutral theory. Several theoretical studies have demonstrated that a slight difference in species per capita birth or death rates can have a profound consequence on species coexistence and community structure. Whether asymmetry in migration, a vital demographic parameter in the neutral model, plays an important role in community assembly still remains unknown. In this paper, we relaxed the ecological equivalence assumption of the neutral model by introducing differences into species regional dispersal ability. We investigated the effect of asymmetric dispersal on the neutral local community structure. We found that per capita asymmetric dispersal among species could reduce species richness of the local community and result in deviations of species abundance distributions from those predicted by the neutral model. But the effect was moderate compared with that of asymmetries in birth or death rates, unless very large asymmetries in dispersal were assumed. A large difference in species dispersal ability, if there is, can overwhelm the role of random drift and make local community dynamics deterministic. In this case, species with higher regional dispersal abilities tended to dominate in the local community. However, the species abundance distribution of the local community under asymmetric dispersal could be well fitted by the neutral model, but the neutral model generally underestimated the fundamental biodiversity number but overestimated the migration rate in such communities.

  10. Lower Limb Neuromuscular Asymmetry in Volleyball and Basketball Players.

    Science.gov (United States)

    Fort-Vanmeerhaeghe, Azahara; Gual, Gabriel; Romero-Rodriguez, Daniel; Unnitha, Viswanath

    2016-04-01

    The primary objective of the present study was to evaluate the agreement between the dominant leg (DL) (determined subjectively) and the stronger leg (SL) (determined via a functional test) in a group of basketball and volleyball players. The secondary objective was to calculate lower limb neuromuscular asymmetry when comparing the DL vs the non-dominant leg (NDL) and the SL vs the weaker (WL) leg in the whole group and when differentiating by sex. Seventy-nine male and female volleyball and basketball players (age: 23.7 ± 4.5 years) performed three single-leg vertical countermovement jumps (SLVCJ) on a contact mat. Vertical jump height and an inter-limb asymmetry index (ASI) were determined. Only 32 (40%) of the subjects had a concordance between the perception of their dominant leg and the limb reaching the highest jump height. Using the DL as the discriminating variable, significant (pjump performance. Vertical jump asymmetry of 10-15% exists and this can be considered as a reference value for male and female basketball and volleyball players.

  11. Attentional sensitivity and asymmetries of vertical saccade generation in monkey

    Science.gov (United States)

    Zhou, Wu; King, W. M.; Shelhamer, M. J. (Principal Investigator)

    2002-01-01

    The first goal of this study was to systematically document asymmetries in vertical saccade generation. We found that visually guided upward saccades have not only shorter latencies, but higher peak velocities, shorter durations and smaller errors. The second goal was to identify possible mechanisms underlying the asymmetry in vertical saccade latencies. Based on a recent model of saccade generation, three stages of saccade generation were investigated using specific behavioral paradigms: attention shift to a visual target (CUED paradigm), initiation of saccade generation (GAP paradigm) and release of the motor command to execute the saccade (DELAY paradigm). Our results suggest that initiation of a saccade (or "ocular disengagement") and its motor release contribute little to the asymmetry in vertical saccade latency. However, analysis of saccades made in the CUED paradigm indicated that it took less time to shift attention to a target in the upper visual field than to a target in the lower visual field. These data suggest that higher attentional sensitivity to targets in the upper visual field may contribute to shorter latencies of upward saccades.

  12. Using CSR to mitigate information asymmetry in the banking sector

    Directory of Open Access Journals (Sweden)

    Semenescu Andreea

    2015-12-01

    Full Text Available The paper examines the power of corporate social responsibility to reduce information asymmetry and to act as a marketing instrument in the banking sector. Trust is the most important asset of a bank. Therefore, banks are motivated to use the most effective instruments to diminish information asymmetry with their stakeholders. The fact that cash disbursements in CSR actions are not directed towards shareholders makes them more valuable signals to other stakeholders regarding the financial soundness of the bank. The empirical study conducted based on limited dependent variable models supports the effectiveness of the CSR as marketing instrument in banking. It reveals the circumstances associated to a higher probability of an active CSR policy conducted by a banking institution. The results support the hypothesis that in the banking sector CSR is perceived as an instrument which helps stakeholders reduce information asymmetry. As marketing instrument, CSR contributes to increasing the tangibility of the banking products, decreasing their perceived variability and thus making them more attractive for the clients and allowing for differentiation between competitors.

  13. Board effectiveness: Investigating payment asymmetry between board members and shareholders

    Directory of Open Access Journals (Sweden)

    Wuchun Chi

    2008-01-01

    Full Text Available Board members may well be responsible for dissension between themselves and shareholders since they are simultaneously the setters and receivers of both board remuneration and dividends. They may act out of their own personal interests at the expense of external shareholders. We investigate the impact of ownership structure, board structure and control deviation on payment asymmetry, where excessively high remuneration is paid to board members but considerably lower dividends are distributed to shareholders. We find strong evidence confirming that the smaller the shareholdings of board members and outside blockholders are, the more asymmetric the payments are. With controlling family members on the board and a higher percentage of seats held by independent board members, there is a slight reduction in the likelihood and severity of payment asymmetry. In addition, it is abundantly clear that the larger the board seat-control deviation is, the greater is the likelihood and severity of payment asymmetry. While prior research has primarily focused on board-manager agency issues, the board-shareholder perspective could be even more important in that it is the board that is the most directly delegated agent of shareholders, not the managers

  14. Directional asymmetries in human smooth pursuit eye movements.

    Science.gov (United States)

    Ke, Sally R; Lam, Jessica; Pai, Dinesh K; Spering, Miriam

    2013-06-27

    Humans make smooth pursuit eye movements to bring the image of a moving object onto the fovea. Although pursuit accuracy is critical to prevent motion blur, the eye often falls behind the target. Previous studies suggest that pursuit accuracy differs between motion directions. Here, we systematically assess asymmetries in smooth pursuit. In experiment 1, binocular eye movements were recorded while observers (n = 20) tracked a small spot of light moving along one of four cardinal or diagonal axes across a featureless background. We analyzed pursuit latency, acceleration, peak velocity, gain, and catch-up saccade latency, number, and amplitude. In experiment 2 (n = 22), we examined the effects of spatial location and constrained stimulus motion within the upper or lower visual field. Pursuit was significantly faster (higher acceleration, peak velocity, and gain) and smoother (fewer and later catch-up saccades) in response to downward versus upward motion in both the upper and the lower visual fields. Pursuit was also more accurate and smoother in response to horizontal versus vertical motion. CONCLUSIONS. Our study is the first to report a consistent up-down asymmetry in human adults, regardless of visual field. Our findings suggest that pursuit asymmetries are adaptive responses to the requirements of the visual context: preferred motion directions (horizontal and downward) are more critical to our survival than nonpreferred ones.

  15. Effects of memory load on hemispheric asymmetries of colour memory.

    Science.gov (United States)

    Clapp, Wes; Kirk, Ian J; Hausmann, Markus

    2007-03-01

    Hemispheric asymmetries in colour perception have been a matter of debate for some time. Recent evidence suggests that lateralisation of colour processing may be largely task specific. Here we investigated hemispheric asymmetries during different types and phases of a delayed colour-matching (recognition) memory task. A total of 11 male and 12 female right-handed participants performed colour-memory tasks. The task involved presentation of a set of colour stimuli (encoding), and subsequent indication (forced choice) of which colours in a larger set had previously appeared at the retrieval or recognition phase. The effect of memory load (set size), and the effect of lateralisation at the encoding or retrieval phases were investigated. Overall, the results indicate a right hemisphere advantage in colour processing, which was particularly pronounced in high memory load conditions, and was seen in males rather than female participants. The results suggest that verbal (mnemonic) strategies can significantly affect the magnitude of hemispheric asymmetries in a non-verbal task.

  16. Using effect size to quantify plantar pressure asymmetry of gait of nondisabled adults and patients with hemiparesis.

    Science.gov (United States)

    Potdevin, François J; Femery, Virginie G; Decatoire, Aurélien; Bosquet, Laurent; Coello, Yann; Moretto, Pierre

    2007-01-01

    In the literature, numerous statistical analyses are used to quantify asymmetry in gait. This study tested the effect size (ES) statistic for quantifying asymmetry in nondisabled and pathological populations. The plantar pressure peaks on eight footprint locations of 27 nondisabled subjects and 18 patients with hemiparesis were bilaterally compared. Asymmetry quantifications were performed with ES and standard statistical tests (index of asymmetry, symmetry index, and ratio index). The results show an advantage in using ES to quantify asymmetry when confidence limits are also calculated. Conversely, traditional asymmetry indexes immediately implied asymmetry without statistical basis. These findings should be considered when one is attempting to diagnose pathological walking patterns or guide rehabilitation processes.

  17. Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing

    Czech Academy of Sciences Publication Activity Database

    Paliwal, S.; Kanagaraj, R.; Sturzenegger, A.; Burdová, Kamila; Janščák, Pavel

    2014-01-01

    Roč. 42, č. 4 (2014), s. 2380-2390 ISSN 0305-1048 R&D Projects: GA ČR GA204/09/0565; GA ČR GAP305/10/0281 Grant - others:Swiss National Science Foundation(CH) 31003A-129747; Swiss National Science Foundation(CH) 31003A_146206 Institutional support: RVO:68378050 Keywords : Human RECQ5 helicase * DNA double-strand breaks * mitotic homologous recombination Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 9.112, year: 2014

  18. DNA strand scission by the novel antitumor antibiotic leinamycin

    International Nuclear Information System (INIS)

    Hara, Mitsunobu; Saitoh, Yutaka; Nakano, Hirofumi

    1990-01-01

    Leinamycin is a recently discovered antitumor antibiotic with an unusual 1,3-dioxo-1,2-dithiolane structure. It preferentially inhibits the incorporation of [ 3 H]thymidine into the acid-insoluble fraction of Bacillus subtilis. In vitro, leinamycin causes single-strand cleavage of supercoiled double-helical pBR322 DNA in the presence of thiol cofactors. Scavengers of oxygen radical did not suppress the DNA-cleaving activity. Thiol-activated leinamycin binds calf thymus DNA at 4 degree C and thermal treatment of the leinamycin-DNA adduct released a chemically modified leinamycin from the complex. The lack of cytotoxicity and DNA-cleaving activity for S-deoxyleinamycin indicates that the 1,3-dioxo-1,2-dithiolane moiety is essential for the activity of leinamycin. Thus, the primary cellular target of leinamycin appears to be DNA. It binds DNA and causes single-strand break at low concentrations, which may account for the potent antitumor activity

  19. Protection of DNA strand breakage by radiation exposure

    International Nuclear Information System (INIS)

    Lee, Jeong Ho; Kim, In Gyu; Lee, Kang Suk; Kim, Kug Chan; Shim, Hae Won

    1997-12-01

    Human ceruloplasmin, the plasma copper containing protein, is thought to play an essential role in iron metabolism, but it also has antioxidant properties. Ceruloplasmin directly scavenged hydroxyl radicals (.OH) generated in dithiothreitol/FeCl 3 system besides inhibitory function of hydroxyl radical formation and lipid peroxidation. Polyamines, spermidine and spermine, significantly protected the supercoiled DNA strand breakage by hydroxyl radicals and DNA strand breakage by UV was highly protected by all four polyamines used in this study. In polyamine deficient mutant KL527. It was shown that cell survivability following UV irradiation was slightly increased by exogenous polyamines putrescine and spermidine supplement. However the cell survivability of wild type (MG 1655) was not influenced by polyamine supplement. In γ-irradiated cells, cell survivability of polyamine-deficient mutant strain KL527 was significantly increased by exogenous putrescine supplement and that of wild type strain MG1655 was similar irrespective of polyamine supplement. These results implicate the possibility that polyamines play a potent role in radioprotection of cell and DNA level. (author). 32 refs., 8 figs

  20. Genome-wide mapping of DNA strand breaks.

    Directory of Open Access Journals (Sweden)

    Frédéric Leduc

    Full Text Available Determination of cellular DNA damage has so far been limited to global assessment of genome integrity whereas nucleotide-level mapping has been restricted to specific loci by the use of specific primers. Therefore, only limited DNA sequences can be studied and novel regions of genomic instability can hardly be discovered. Using a well-characterized yeast model, we describe a straightforward strategy to map genome-wide DNA strand breaks without compromising nucleotide-level resolution. This technique, termed "damaged DNA immunoprecipitation" (dDIP, uses immunoprecipitation and the terminal deoxynucleotidyl transferase-mediated dUTP-biotin end-labeling (TUNEL to capture DNA at break sites. When used in combination with microarray or next-generation sequencing technologies, dDIP will allow researchers to map genome-wide DNA strand breaks as well as other types of DNA damage and to establish a clear profiling of altered genes and/or intergenic sequences in various experimental conditions. This mapping technique could find several applications for instance in the study of aging, genotoxic drug screening, cancer, meiosis, radiation and oxidative DNA damage.