WorldWideScience

Sample records for repeatable sex ratios

  1. Sex ratios

    OpenAIRE

    West, Stuart A; Reece, S E; Sheldon, Ben C

    2002-01-01

    Sex ratio theory attempts to explain variation at all levels (species, population, individual, brood) in the proportion of offspring that are male (the sex ratio). In many cases this work has been extremely successful, providing qualitative and even quantitative explanations of sex ratio variation. However, this is not always the situation, and one of the greatest remaining problems is explaining broad taxonomic patterns. Specifically, why do different organisms show so ...

  2. Sex Ratio Elasticity Influences the Selection of Sex Ratio Strategy

    Science.gov (United States)

    Wang, Yaqiang; Wang, Ruiwu; Li, Yaotang; (Sam) Ma, Zhanshan

    2016-12-01

    There are three sex ratio strategies (SRS) in nature—male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton’s local mate competition (LMC) and Clark’s local resource competition (LRC) separately explained the observed deviations from the seemingly universal 1:1 ratio. However, to the best of our knowledge, there is not yet a unified theory that accounts for the mechanisms of the three SRS. Here, we introduce the price elasticity theory in economics to define sex ratio elasticity (SRE), and present an analytical model that derives three SRSs based on the following assumption: simultaneously existing competitions for both resources A and resources B influence the level of SRE in both sexes differently. Consequently, it is the difference (between two sexes) in the level of their sex ratio elasticity that leads to three different SRS. Our analytical results demonstrate that the elasticity-based model not only reveals a highly plausible mechanism that explains the evolution of SRS in nature, but also offers a novel framework for unifying two major classical theories (i.e., LMC & LRC) in the field of SRS research.

  3. Sex chromosome repeats tip the balance towards speciation.

    Science.gov (United States)

    O'Neill, Michael J; O'Neill, Rachel J

    2018-04-06

    Because sex chromosomes, by definition, carry genes that determine sex, mutations that alter their structural and functional stability can have immediate consequences for the individual by reducing fertility, but also for a species by altering the sex ratio. Moreover, the sex-specific segregation patterns of heteromorphic sex chromosomes make them havens for selfish genetic elements that not only create sub-optimal sex ratios, but can also foster sexual antagonism. Compensatory mutations to mitigate antagonism or return sex ratios to a Fisherian optimum can create hybrid incompatibility and establish reproductive barriers leading to species divergence. The destabilizing influence of these selfish elements is often manifest within populations as copy number variants (CNVs) in satellite repeats and transposable elements (TE) or as CNVs involving sex determining genes, or genes essential to fertility and sex chromosome dosage compensation. This review catalogs several examples of well-studied sex chromosome CNVs in Drosophilids and mammals that underlie instances of meiotic drive, hybrid incompatibility and disruptions to sex differentiation and sex chromosome dosage compensation. While it is difficult to pinpoint a direct cause/effect relationship between these sex chromosome CNVs and speciation, it is easy to see how their effects in creating imbalances between the sexes, and the compensatory mutations to restore balance, can lead to lineage splitting and species formation. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  4. The evolution of sex ratios and sex-determining systems

    NARCIS (Netherlands)

    Uller, Tobias; Pen, Ido; Wapstra, Erik; Beukeboom, Leo W.; Komdeur, Jan

    Sex determination is a fundamental process governed by diverse mechanisms. Sex ratio selection is commonly implicated in the evolution of sex-determining systems, although formal models are rare. Here, we argue that, although sex ratio selection can induce shifts in sex determination, genomic

  5. Sex Determination, Sex Ratios, and Genetic Conflict

    NARCIS (Netherlands)

    Werren, John H.; Beukeboom, Leo W.

    1998-01-01

    Genetic mechanisms of sex determination are unexpectedly diverse and change rapidly during evolution. We review the role of genetic conflict as the driving force behind this diversity and turnover. Genetic conflict occurs when different components of a genetic system are subject to selection in

  6. Curious Sex Ratios and Cytoplasmic Genes

    Indian Academy of Sciences (India)

    instances of curious sex ratios exemplify an important principle: the fitness ..... markable transition - the whole means of sex determination has changed. No longer ... to the cytoplasmic symbiont is self-evident; the symbionts simply increase the.

  7. Great tit hatchling sex ratios

    NARCIS (Netherlands)

    Lessells, C.M.; Mateman, A.C.; Visser, J.

    1996-01-01

    The sex of Great Tit Parus major nestlings was determined using PCR RAPDs. Because this technique requires minute amounts of DNA, chicks could be sampled soon (0-2d) after hatching, before any nestling mortality occurred. The proportion of males among 752 chicks hatching in 102 broods (98.9% of

  8. Curious Sex Ratios and Cytoplasmic Genes

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 6. Curious Sex Ratios and Cytoplasmic Genes Microbes Can Distort the Sex Ratio of Populations. Stephen J Freeland Laurence D Hurst. General Article Volume 2 Issue 6 June 1997 pp 68-78 ...

  9. Sex ratio variation and sex determination in Urtica dioica

    NARCIS (Netherlands)

    Glawe, Grit Anja

    2006-01-01

    This thesis will first document on variation in progeny sex ratios among individual female plants of Urtica dioica at our field site in Meijendel (Chapter 2). Next, we show that there is also considerable sex ratio variation among male and female flowering shoots in 26 natural populations studied

  10. Determining sex ratios of turtle hatchlings

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Previous status assessments of marine turtles have assumed that the natural sex ratio of a marine turtle population is 1:1 (e.g. Conant et al. 2009). However, this...

  11. Maternal preconception diet and the sex ratio

    NARCIS (Netherlands)

    Cramer, J.S.; Lumey, L.H.

    2009-01-01

    Temporal variations in the sex ratio or the ratio of boys over girls at birth have been widely studied and variously attributed to social changes, conditions of war, and environmental changes. Recently, Mathews, Johnson and Neil (2008) studied the direct evidence of individual pregnancies and

  12. Maternal preconception diet and the sex ratio

    NARCIS (Netherlands)

    Cramer, J.S.; Lumey, L.H.

    2010-01-01

    Temporal variations in the sex ratio, or the ratio of boys to girls at birth, have been widely studied and variously attributed to social changes, conditions of war, and environmental changes. Recently, Mathews et al. ["You are what your mother eats: Evidence for maternal preconception diet

  13. Mother's occupation and sex ratio at birth

    Directory of Open Access Journals (Sweden)

    Amiot Volodymyr

    2010-05-01

    Full Text Available Abstract Background Many women are working outside of the home, occupying a multitude of jobs with varying degrees of responsibilities and levels of psychological stress. We investigated whether different job types in women are associated with child sex at birth, with the hypothesis that women in job types, which are categorized as "high psychological stress" jobs, would be more likely to give birth to a daughter than a son, as females are less vulnerable to unfavourable conditions during conception, pregnancy and after parturition, and are less costly to carry to term. Methods We investigated the effects of mother's age, maternal and paternal job type (and associated psychological stress levels and paternal income on sex ratio at birth. Our analyses were based on 16,384 incidences of birth from a six-year (2000 to 2005 inclusive childbirth dataset from Addenbrooke's Hospital in Cambridge, UK. We obtained a restricted data set from Addenbrooke's hospital with: maternal age, maternal and paternal occupations, and whether or not the child was first-born. Results Women in job types that were categorized as "high stress" were more likely to give birth to daughters, whereas women in job types that were categorized as "low stress" had equal sex ratios or a slight male bias in offspring. We also investigated whether maternal age, and her partner's income could be associated with reversed offspring sex ratio. We found no association between mother's age, her partner's job stress category or partner income on child sex. However, there was an important interaction between job stress category and partner income in some of the analyses. Partner income appears to attenuate the association between maternal job stress and sex ratios at moderate-income levels, and reverse it at high-income levels. Conclusions To our knowledge this is the first report on the association between women's job type stress categories and offspring sex ratio in humans, and the

  14. Invited review: sex ratio and rheumatic disease.

    Science.gov (United States)

    Lockshin, M D

    2001-11-01

    Human illnesses affect men and women differently. In some cases (diseases of sex organs, diseases resulting from X or Y chromosome mutations), reasons for sex discrepancy are obvious, but in other cases no reason is apparent. Explanations for sex discrepancy of illness occur at different biological levels: molecular (e.g., imprinting, X-inactivation), cellular (sex-specific receptor activity), organ (endocrine influences), whole organism (size, age), and environmental-behavioral, including intrauterine influences. Autoimmunity represents a prototypical class of illness that has high female-to-male (F/M) ratios. Although the F/M ratios in autoimmune diseases are usually attributed to the influence of estrogenic hormones, evidence demonstrates that the attributed ratios are imprecise and that definitions and classifications of autoimmune diseases vary, rendering at least part of the counting imprecise. In addition, many studies on sex discrepancy of human disease fail to distinguish between disease incidence and disease severity. In April 2001, the Institute of Medicine of the National Academy of Sciences published Exploring the Biological Contributions to Human Health: Does Sex Matter? (Wizemann T and Pardue M-L, editors). This minireview summarizes the section of that report that concerns autoimmune and infectious disease. Some thyroid, rheumatic, and hepatic autoimmune diseases have high F/M ratios, whereas others have low. Those that have high ratios occur primarily in young adulthood. Gonadal hormones, if they play a role, likely do so through a threshold or permissive mechanism. Examples of sex differences that could be caused by environmental exposure, X inactivation, imprinting, X or Y chromosome genetic modulators, and intrauterine influences are presented as alternate, theoretical, and largely unexplored explanations for sex differences of incidence. The epidemiology of autoimmune diseases (young, female) suggests that an explanation for sex discrepancy of

  15. Repeated in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure affects male gonads in offspring, leading to sex ratio changes in F2 progeny

    International Nuclear Information System (INIS)

    Ikeda, Masahiko; Tamura, Masashi; Yamashita, Junko; Suzuki, Chinatsu; Tomita, Takako

    2005-01-01

    The effects of in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the reproductive system of male rat offspring (F 1 ) and the sex ratio of the subsequent generation (F 2 ) were examined. Female Holtzman rats were gavaged with an initial loading dose of 400 ng/kg TCDD prior to mating, followed by weekly maintenance doses of 80 ng/kg during mating, pregnancy, and the lactation period. Maternal exposure to TCDD had no significant effects on fetus/pup (F 1 ) mortality, litter size, or sex ratio on gestation day (GD) 20 or postnatal day (PND) 2. The TCDD concentration in maternal livers and adipose tissue on GD20 was 1.21 and 1.81 ng/kg, respectively, and decreased at weaning to 0.72 in the liver and 0.84 in the adipose tissue. In contrast, the TCDD concentration in pup livers was 1.32 ng/kg on PND2 and increased to 1.80 ng/kg at weaning. Ventral prostate weight of male offspring was significantly decreased by TCDD exposure on PND28 and 120 compared with that of controls. Weight of the testes, cauda epididymides, and seminal vesicle, and sperm number in the cauda epididymis were not changed by TCDD exposure at PND120. TCDD- or vehicle-exposed male offspring were mated with unexposed females. The sex ratio (percentage of male pups) of F 2 offspring was significantly reduced in the TCDD-exposed group compared with controls. These results suggest that in utero and lactational TCDD exposures affect the development of male gonads in offspring (F 1 ), leading to changes in the sex ratio of the subsequent generation (F 2 )

  16. Sex ratios at birth after induced abortion.

    Science.gov (United States)

    Urquia, Marcelo L; Moineddin, Rahim; Jha, Prabhat; O'Campo, Patricia J; McKenzie, Kwame; Glazier, Richard H; Henry, David A; Ray, Joel G

    2016-06-14

    Skewed male:female ratios at birth have been observed among certain immigrant groups. Data on abortion practices that might help to explain these findings are lacking. We examined 1 220 933 births to women with up to 3 consecutive singleton live births between 1993 and 2012 in Ontario. Records of live births, and induced and spontaneous abortions were linked to Canadian immigration records. We determined associations of male:female infant ratios with maternal birthplace, sex of the previous living sibling(s) and prior spontaneous or induced abortions. Male:female infant ratios did not appreciably depart from the normal range among Canadian-born women and most women born outside of Canada, irrespective of the sex of previous children or the characteristics of prior abortions. However, among infants of women who immigrated from India and had previously given birth to 2 girls, the overall male:female ratio was 1.96 (95% confidence interval [CI] 1.75-2.21) for the third live birth. The male:female infant ratio after 2 girls was 1.77 (95% CI 1.26-2.47) times higher if the current birth was preceded by 1 induced abortion, 2.38 (95% CI 1.44-3.94) times higher if preceded by 2 or more induced abortions and 3.88 (95% CI 2.02-7.50) times higher if the induced abortion was performed at 15 weeks or more gestation relative to no preceding abortion. Spontaneous abortions were not associated with male-biased sex ratios in subsequent births. High male:female ratios observed among infants born to women who immigrated from India are associated with induced abortions, especially in the second trimester of pregnancy. © 2016 Canadian Medical Association or its licensors.

  17. Female-biased sex ratios in marine pelagic copepods: Comment on Gusmao et al. (2013)

    DEFF Research Database (Denmark)

    Hirst, Andrew G.; Bonnet, D; Conway, DVP

    2013-01-01

    Gusmao et al. (2013; Mar Ecol Prog Ser 482:279-298) review causes of sex ratio skew in pelagic copepods and in doing so repeatedly dispute the paper of Hirst et al. (2010) ‘Does predation control adult sex ratios and longevities in marine pelagic copepods?’ Here we respond to some important error...... in their citation of our paper and briefly highlight where future work is needed in order to attribute the causes of strong sex ratio skew seen in some copepod families......Gusmao et al. (2013; Mar Ecol Prog Ser 482:279-298) review causes of sex ratio skew in pelagic copepods and in doing so repeatedly dispute the paper of Hirst et al. (2010) ‘Does predation control adult sex ratios and longevities in marine pelagic copepods?’ Here we respond to some important errors...

  18. Do Workplace Sex Ratios Affect Partnership Formation and Dissolution?

    DEFF Research Database (Denmark)

    Svarer, Michael

    In this paper, I analyse the association between workplace sex ratios and partnership formation and dissolution. I find that the risk of dissolution increases with the fraction of coworkers of the opposite sex at both the female and male workplace. On the other hand, workplace sex ratios are not ......In this paper, I analyse the association between workplace sex ratios and partnership formation and dissolution. I find that the risk of dissolution increases with the fraction of coworkers of the opposite sex at both the female and male workplace. On the other hand, workplace sex ratios...

  19. Sex ratios of Mountain Plovers from egg production to fledging

    Directory of Open Access Journals (Sweden)

    Margaret M. Riordan

    2015-12-01

    Full Text Available Skewed sex ratios can have negative implications for population growth if they do not match a species' life history. A skewed tertiary sex ratio has been detected in a population of Mountain Plover (Charadrius montanus, a grassland shorebird experiencing population declines. To study the cause of the observed male skew, we examined three early life stages between egg and fledgling in eastern Colorado from 2010 to 2012. This allows us to distinguish between egg production and chick survival as an explanation for the observed skew. We examined the primary sex ratio in eggs produced and the secondary sex ratio in hatched chicks to see if the sex ratio bias occurs before hatching. We also determined the sex ratio at fledging to reveal sex-specific mortality of nestlings. The primary sex ratio was 1.01 (± 0.01 males per female. The secondary sex ratio consisted of 1.10 (± 0.02 males per female. The probability of a chick surviving to fledging differed between males (0.55 ± 0.13 and females (0.47 ± 0.15, but the precision of these survival estimates was low. Sex ratios in early life stages of the Mountain Plover do not explain the skewed sex ratio observed in adults in this breeding population.

  20. A father effect explains sex-ratio bias.

    Science.gov (United States)

    Malo, Aurelio F; Martinez-Pastor, Felipe; Garcia-Gonzalez, Francisco; Garde, Julián; Ballou, Jonathan D; Lacy, Robert C

    2017-08-30

    Sex ratio allocation has important fitness consequences, and theory predicts that parents should adjust offspring sex ratio in cases where the fitness returns of producing male and female offspring vary. The ability of fathers to bias offspring sex ratios has traditionally been dismissed given the expectation of an equal proportion of X- and Y-chromosome-bearing sperm (CBS) in ejaculates due to segregation of sex chromosomes at meiosis. This expectation has been recently refuted. Here we used Peromyscus leucopus to demonstrate that sex ratio is explained by an exclusive effect of the father, and suggest a likely mechanism by which male-driven sex-ratio bias is attained. We identified a male sperm morphological marker that is associated with the mechanism leading to sex ratio bias; differences among males in the sperm nucleus area (a proxy for the sex chromosome that the sperm contains) explain 22% variation in litter sex ratio. We further show the role played by the sperm nucleus area as a mediator in the relationship between individual genetic variation and sex-ratio bias. Fathers with high levels of genetic variation had ejaculates with a higher proportion of sperm with small nuclei area. This, in turn, led to siring a higher proportion of sons (25% increase in sons per 0.1 decrease in the inbreeding coefficient). Our results reveal a plausible mechanism underlying unexplored male-driven sex-ratio biases. We also discuss why this pattern of paternal bias can be adaptive. This research puts to rest the idea that father contribution to sex ratio variation should be disregarded in vertebrates, and will stimulate research on evolutionary constraints to sex ratios-for example, whether fathers and mothers have divergent, coinciding, or neutral sex allocation interests. Finally, these results offer a potential explanation for those intriguing cases in which there are sex ratio biases, such as in humans. © 2017 The Author(s).

  1. Human sex ratio at amniocentesis and at birth in Taiwan

    Directory of Open Access Journals (Sweden)

    I-Wen Lee

    2012-12-01

    Conclusions: The results showed that sex ratio was already skewed toward male at midtrimester. Our data imply that artificial sex selection, if it were present, might have already emerged prior to the timing of amniocentesis. However, more large nationwide studies on sex ratios in Taiwan are warranted.

  2. Sex ratio and Wolbachia infection in the ant Formica exsecta.

    Science.gov (United States)

    Keller, L; Liautard, C; Reuter, M; Brown, W D; Sundström, L; Chapuisat, M

    2001-08-01

    Sex allocation data in social Hymenoptera provide some of the best tests of kin selection, parent-offspring conflict and sex ratio theories. However, these studies critically depend on controlling for confounding ecological factors and on identifying all parties that potentially manipulate colony sex ratio. It has been suggested that maternally inherited parasites may influence sex allocation in social Hymenoptera. If the parasites can influence sex allocation, infected colonies are predicted to invest more resources in females than non-infected colonies, because the parasites are transmitted through females but not males. Prime candidates for such sex ratio manipulation are Wolbachia, because these cytoplasmically transmitted bacteria have been shown to affect the sex ratio of host arthropods by cytoplasmic incompatibility, parthenogenesis, male-killing and feminization. In this study, we tested whether Wolbachia infection is associated with colony sex ratio in two populations of the ant Formica exsecta that have been the subject of extensive sex ratio studies. In these populations colonies specialize in the production of one sex or the other. We found that almost all F. exsecta colonies in both populations are infected with Wolbachia. However, in neither population did we find a significant association in the predicted direction between the prevalence of Wolbachia and colony sex ratio. In particular, colonies with a higher proportion of infected workers did not produce more females. Hence, we conclude that Wolbachia does not seem to alter the sex ratio of its hosts as a means to increase transmission rate in these two populations of ants.

  3. Breeding sex ratio and population size of loggerhead turtles from Southwestern Florida.

    Directory of Open Access Journals (Sweden)

    Jacob A Lasala

    Full Text Available Species that display temperature-dependent sex determination are at risk as a result of increasing global temperatures. For marine turtles, high incubation temperatures can skew sex ratios towards females. There are concerns that temperature increases may result in highly female-biased offspring sex ratios, which would drive a future sex ratio skew. Studying the sex ratios of adults in the ocean is logistically very difficult because individuals are widely distributed and males are inaccessible because they remain in the ocean. Breeding sex ratios (BSR are sought as a functional alternative to study adult sex ratios. One way to examine BSR is to determine the number of males that contribute to nests. Our goal was to evaluate the BSR for loggerhead turtles (Caretta caretta nesting along the eastern Gulf of Mexico in Florida, from 2013-2015, encompassing three nesting seasons. We genotyped 64 nesting females (approximately 28% of all turtles nesting at that time and up to 20 hatchlings from their nests (n = 989 using 7 polymorphic microsatellite markers. We identified multiple paternal contributions in 70% of the nests analyzed and 126 individual males. The breeding sex ratio was approximately 1 female for every 2.5 males. We did not find repeat males in any of our nests. The sex ratio and lack of repeating males was surprising because of female-biased primary sex ratios. We hypothesize that females mate offshore of their nesting beaches as well as en route. We recommend further comparisons of subsequent nesting events and of other beaches as it is imperative to establish baseline breeding sex ratios to understand how growing populations behave before extreme environmental effects are evident.

  4. Local offspring density and sex ratio affect sex allocation in the great tit

    NARCIS (Netherlands)

    Michler, Stephanie P. M.; Nicolaus, Marion; van der Velde, Marco; Radersma, Reinder; Ubels, Richard; Both, Christiaan; Komdeur, Jan; Tinbergen, Joost M.

    2013-01-01

    The expected fitness gain for offspring of a given sex may depend on local population sex ratio and density. Knowing the influence of such social factors on brood sex ratios may contribute considerably to the understanding of sex allocation in higher vertebrates. For 3 consecutive years, we

  5. Adult sex ratio variation : Implications for breeding system evolution

    NARCIS (Netherlands)

    Szekely, T.; Weissing, F. J.; Komdeur, J.

    Adult sex ratio (ASR) exhibits immense variation in nature, although neither the causes nor the implications of this variation are fully understood. According to theory, the ASR is expected to influence sex roles and breeding systems, as the rarer sex in the population has more potential partners to

  6. Parental correlates of offspring sex ratio in Eurasian Oystercatchers

    NARCIS (Netherlands)

    Heg, D.; Dingemanse, NJ; Lessells, CM; Mateman, AC

    2000-01-01

    We investigated hatchling and fledgling sex ratios in Eurasian Oystercatchers (Haematopus ostralegus) using random amplified polymorphic DNA markers. The overall hatchling (53% males, n = 374 hatchlings from 177 broods) and fledgling (49% males, n = 51) sex ratio did not differ significantly from

  7. Sex ratio, gonadal development and fecundity of the grunt ...

    African Journals Online (AJOL)

    The sex ratio, gonadosomatic index, stages of gonadal development and fecundity of the grunt, Pomadasys jubelini in the New Calabar-Bonny River were investigated. P. jubelini had a sex ratio of 1: 2.1 (male to female). Gonadosomatic index ranged from 0.33 to 7.29% with a mean of 2.89+0.08%. High gonadosomatic ...

  8. Exploring the possibilities for stabilizing the sex ratio in India

    Directory of Open Access Journals (Sweden)

    Saurabh RamBihariLal Shrivastava

    2015-12-01

    Full Text Available The sex ratio is an important demographic indicator for a nation. A wide range of adverse social consequences have been observed because of a skewed sex ratio in India. If India as a nation is to achieve the Millennium Development Goal – 3 (which promotes gender equality and ensures the empowerment of women, the primary target should be involve all those involved, so that a collective and comprehensive approach can be developed to counter the public health menace of an asymmetrical sex ratio. In conclusion, the nation’s program managers should prioritize the issue of a skewed sex ratio and work towards developing a coordinated response.Key Words: Sex ratio, policy makers, India.

  9. Sex ratio selection and multi-factorial sex determination in the housefly : A dynamic model

    NARCIS (Netherlands)

    Kozielska, M.A.; Pen, I.R.; Beukeboom, L.W.; Weissing, F.J.

    Sex determining (SD) mechanisms are highly variable between different taxonomic groups and appear to change relatively quickly during evolution. Sex ratio selection could be a dominant force causing such changes. We investigate theoretically the effect of sex ratio selection on the dynamics of a

  10. Patterns of Family Formation in Response to Sex Ratio Variation.

    Science.gov (United States)

    Schacht, Ryan; Kramer, Karen L

    2016-01-01

    The impact that unbalanced sex ratios have on health and societal outcomes is of mounting contemporary concern. However, it is increasingly unclear whether it is male- or female-biased sex ratios that are associated with family and social instability. From a socio-demographic perspective, male-biased sex ratios leave many men unable to find a mate, elevating competition among males, disrupting family formation and negatively affecting social stability. In contrast, from a mating-market perspective, males are expected to be less willing to marry and commit to a family when the sex ratio is female-biased and males are rare. Here we use U.S. data to evaluate predictions from these competing frameworks by testing the relationship between the adult sex ratio and measures of family formation. We find that when women are rare men are more likely to marry, be part of a family and be sexually committed to a single partner. Our results do not support claims that male-biased sex ratios lead to negative family outcomes due to a surplus of unmarried men. Rather, our results highlight the need to pay increased attention to female-biased sex ratios.

  11. Sex ratios in fetuses and liveborn infants with autosomal aneuploidy

    Energy Technology Data Exchange (ETDEWEB)

    Heuther, C.A.; Martin, R.L.M.; Stoppelman, S.M. [Univ. of Cincinnati, OH (United States)] [and others

    1996-06-14

    Ten data sources were used substantially to increase the available data for estimating fetal and livebirth sex ratios for Patau (trisomy 13), Edwards (trisomy 18), and Down (trisomy 21) syndromes and controls. The fetal sex ratio estimate was 0.88 (N = 584) for trisomy 13, 0.90 (N = 1702) for trisomy 18, and 1.16 (N = 3154) for trisomy 21. All were significantly different from prenatal controls (1.07). The estimated ratios in prenatal controls were 1.28 (N = 1409) for CVSs and 1.06 (N = 49427) for amniocenteses, indicating a clear differential selection against males, mostly during the first half of fetal development. By contrast, there were no sex ratio differences for any of the trisomies when comparing gestational ages <16 and >16 weeks. The livebirth sex ratio estimate was 0.90 (N = 293) for trisomy 13, 0.63 (N = 497) for trisomy 18, and 1.15 (N = 6424) for trisomy 21, the latter two being statistically different than controls (1.05) (N = 3660707). These ratios for trisomies 13 and 18 were also statistically different than the ratio for trisomy 21. Only in trisomy 18 did the sex ratios in fetuses and livebirths differ, indicating a prenatal selection against males >16 weeks. No effects of maternal age or race were found on these estimates for any of the fetal or livebirth trisomies. Sex ratios for translocations and mosaics were also estimated for these aneuploids. Compared to previous estimates, these results are less extreme, most likely because of larger sample sizes and less sample bias. They support the hypothesis that these trisomy sex ratios are skewed at conception, or become so during embryonic development through differential intrauterine selection. The estimate for Down syndrome livebirths is also consistent with the hypothesis that its higher sex ratio is associated with paternal nondisjunction. 36 refs., 5 tabs.

  12. Demographic origins of skewed operational and adult sex ratios: perturbation analyses of two-sex models.

    Science.gov (United States)

    Veran, Sophie; Beissinger, Steven R

    2009-02-01

    Skewed sex ratios - operational (OSR) and Adult (ASR) - arise from sexual differences in reproductive behaviours and adult survival rates due to the cost of reproduction. However, skewed sex-ratio at birth, sex-biased dispersal and immigration, and sexual differences in juvenile mortality may also contribute. We present a framework to decompose the roles of demographic traits on sex ratios using perturbation analyses of two-sex matrix population models. Metrics of sensitivity are derived from analyses of sensitivity, elasticity, life-table response experiments and life stage simulation analyses, and applied to the stable stage distribution instead of lambda. We use these approaches to examine causes of male-biased sex ratios in two populations of green-rumped parrotlets (Forpus passerinus) in Venezuela. Female local juvenile survival contributed the most to the unbalanced OSR and ASR due to a female-biased dispersal rate, suggesting sexual differences in philopatry can influence sex ratios more strongly than the cost of reproduction.

  13. Psychological distress during early gestation and offspring sex ratio

    DEFF Research Database (Denmark)

    Obel, C; Henriksen, TB; Secher, Niels Jørgen

    2007-01-01

    BACKGROUND: Exposure to severe stress in early pregnancy is associated with a lower male to female ratio (sex ratio), but whether more moderate levels of psychological discomfort have the same kind of effect is unknown. In a population based follow-up study, we aimed to test whether psychological...... suggest that not only severe stress, but also more moderate and common levels of psychological distress, may decrease the sex ratio in the offspring. Stress during pregnancy is a likely candidate involved in the decreasing sex ratio observed in many countries....... distress was associated with the sex ratio in the offspring. METHODS: From 1989 to 1992, a cohort of 8,719 Danish-speaking pregnant women were followed until delivery. Questionnaires were administered to the women in early pregnancy and 6,629 (76%) completed the 30-item version of the General Health...

  14. Psychological distress during early gestation and offspring sex ratio

    DEFF Research Database (Denmark)

    Obel, Carsten; Henriksen, Tine Brink; Secher, Niels Jørgen

    2007-01-01

    BACKGROUND: Exposure to severe stress in early pregnancy is associated with a lower male to female ratio (sex ratio), but whether more moderate levels of psychological discomfort have the same kind of effect is unknown. In a population based follow-up study, we aimed to test whether psychological...... suggest that not only severe stress, but also more moderate and common levels of psychological distress, may decrease the sex ratio in the offspring. Stress during pregnancy is a likely candidate involved in the decreasing sex ratio observed in many countries. Udgivelsesdato: 2007-Nov...... distress was associated with the sex ratio in the offspring. METHODS: From 1989 to 1992, a cohort of 8,719 Danish-speaking pregnant women were followed until delivery. Questionnaires were administered to the women in early pregnancy and 6,629 (76%) completed the 30-item version of the General Health...

  15. Heritable Variation for Sex Ratio under Environmental Sex Determination in the Common Snapping Turtle (Chelydra Serpentina)

    Science.gov (United States)

    Janzen, F. J.

    1992-01-01

    The magnitude of quantitative genetic variation for primary sex ratio was measured in families extracted from a natural population of the common snapping turtle (Chelydra serpentina), which possesses temperature-dependent sex determination (TSD). Eggs were incubated at three temperatures that produced mixed sex ratios. This experimental design provided estimates of the heritability of sex ratio in multiple environments and a test of the hypothesis that genotype X environment (G X E) interactions may be maintaining genetic variation for sex ratio in this population of C. serpentina. Substantial quantitative genetic variation for primary sex ratio was detected in all experimental treatments. These results in conjunction with the occurrence of TSD in this species provide support for three critical assumptions of Fisher's theory for the microevolution of sex ratio. There were statistically significant effects of family and incubation temperature on sex ratio, but no significant interaction was observed. Estimates of the genetic correlations of sex ratio across environments were highly positive and essentially indistinguishable from +1. These latter two findings suggest that G X E interaction is not the mechanism maintaining genetic variation for sex ratio in this system. Finally, although substantial heritable variation exists for primary sex ratio of C. serpentina under constant temperatures, estimates of the effective heritability of primary sex ratio in nature are approximately an order of magnitude smaller. Small effective heritability and a long generation time in C. serpentina imply that evolution of sex ratios would be slow even in response to strong selection by, among other potential agents, any rapid and/or substantial shifts in local temperatures, including those produced by changes in the global climate. PMID:1592234

  16. Extraordinary sex ratios: cultural effects on ecological consequences.

    Directory of Open Access Journals (Sweden)

    Ferenc Molnár

    Full Text Available We model sex-structured population dynamics to analyze pairwise competition between groups differing both genetically and culturally. A sex-ratio allele is expressed in the heterogametic sex only, so that assumptions of Fisher's analysis do not apply. Sex-ratio evolution drives cultural evolution of a group-associated trait governing mortality in the homogametic sex. The two-sex dynamics under resource limitation induces a strong Allee effect that depends on both sex ratio and cultural trait values. We describe the resulting threshold, separating extinction from positive growth, as a function of female and male densities. When initial conditions avoid extinction due to the Allee effect, different sex ratios cannot coexist; in our model, greater female allocation always invades and excludes a lesser allocation. But the culturally transmitted trait interacts with the sex ratio to determine the ecological consequences of successful invasion. The invading female allocation may permit population persistence at self-regulated equilibrium. For this case, the resident culture may be excluded, or may coexist with the invader culture. That is, a single sex-ratio allele in females and a cultural dimorphism in male mortality can persist; a low-mortality resident trait is maintained by father-to-son cultural transmission. Otherwise, the successfully invading female allocation excludes the resident allele and culture and then drives the population to extinction via a shortage of males. Finally, we show that the results obtained under homogeneous mixing hold, with caveats, in a spatially explicit model with local mating and diffusive dispersal in both sexes.

  17. Male lifespan and the secondary sex ratio.

    Science.gov (United States)

    Catalano, Ralph; Bruckner, Tim

    2006-01-01

    Literature speculating on the fetal origins of later life morbidity often invokes the "damaged cohort" theory, i.e., that maternal responses to exogenous shocks induce "stress reactivity" in fetuses and thereby shorten the lifespan of males in utero during stressful times. A rival, or "culled cohort," theory posits that exogenous shocks to gravid females induce spontaneous abortions of frail male fetuses, leaving relatively hardy survivors who enjoy, on average, lifespans longer than males in less stressed birth cohorts. A recent test based on archival data from Sweden supported the culled cohort theory. Several characteristics of the Swedish data, however, raise questions regarding the external validity of the findings. We repeat the test with data from Denmark, Iceland, and England and Wales. We use time-series methods that control for trends, seasonal cycles, and other forms of autocorrelation that could confound the test. None of the results supports the "damaged cohort" theory. Consistent with the Swedish findings and with evolutionary theory, we find support in Iceland and England and Wales for the "culled cohort" theory. We discuss the implications of our findings for basic research as well as for public health.

  18. Sex ratio distribution and fecundity of the claroteid catfish Clarotes ...

    African Journals Online (AJOL)

    Sex ratio distribution and fecundity of Clarotes laticeps were investigated between January 2010 and December 2012 in the lower River Niger. Samples were collected every two weeks for 36 months from six sampling sites, using a combination of baited longlines, gill nets and cast nets. Sexes of captured specimens were ...

  19. Skewed sex ratios in India: "physician, heal thyself".

    Science.gov (United States)

    Patel, Archana B; Badhoniya, Neetu; Mamtani, Manju; Kulkarni, Hemant

    2013-06-01

    Sex selection, a gender discrimination of the worst kind, is highly prevalent across all strata of Indian society. Physicians have a crucial role in this practice and implementation of the Indian Government's Pre-Natal Diagnostic Techniques Act in 1996 to prevent the misuse of ultrasound techniques for the purpose of prenatal sex determination. Little is known about family preferences, let alone preferences among families of physicians. We investigated the sex ratios in 946 nuclear families with 1,624 children, for which either one or both parents were physicians. The overall child sex ratio was more skewed than the national average of 914. The conditional sex ratios decreased with increasing number of previous female births, and a previous birth of a daughter in the family was associated with a 38 % reduced likelihood of a subsequent female birth. The heavily skewed sex ratios in the families of physicians are indicative of a deeply rooted social malady that could pose a critical challenge in correcting the sex ratios in India.

  20. Gender Inequality and the Sex Ratio in Three Emerging Economies

    OpenAIRE

    Prabir C. Bhattacharya

    2012-01-01

    The aim of this paper is to study inequality and deprivations as reflected in the human sex ratio (commonly defined as the number of males per 100 females). The particular focus is on three emerging economies, viz., Russia, India and China. The paper compares and contrasts the experiences of these countries and discusses policy issues. It is noted that while the feminist perspective on the issues surrounding the sex ratio is important, it would be wrong to view these issues always or exclusiv...

  1. Skewed Sex Ratios and Criminal Victimization in India

    Science.gov (United States)

    South, Scott J.; Trent, Katherine; Bose, Sunita

    2014-01-01

    Although substantial research has explored the causes of India’s excessively masculine population sex ratio, few studies have examined the consequences of this surplus of males. We merge individual-level data from the 2004–2005 India Human Development Survey with data from the 2001 India population census to examine the association between the district-level male-to-female sex ratio at ages 15 to 39 and self-reports of victimization by theft, breaking and entering, and assault. Multilevel logistic regression analyses reveal positive and statistically significant albeit substantively modest effects of the district-level sex ratio on all three victimization risks. We also find that higher male-to-female sex ratios are associated with the perception that young unmarried women in the local community are frequently harassed. Household-level indicators of family structure, socioeconomic status, and caste, as well as areal indicators of women’s empowerment and collective efficacy, also emerge as significant predictors of self-reported criminal victimization and the perceived harassment of young women. The implications of these findings for India’s growing sex ratio imbalance are discussed. PMID:24682921

  2. Skewed sex ratios and criminal victimization in India.

    Science.gov (United States)

    South, Scott J; Trent, Katherine; Bose, Sunita

    2014-06-01

    Although substantial research has explored the causes of India's excessively masculine population sex ratio, few studies have examined the consequences of this surplus of males. We merge individual-level data from the 2004-2005 India Human Development Survey with data from the 2001 India population census to examine the association between the district-level male-to-female sex ratio at ages 15 to 39 and self-reports of victimization by theft, breaking and entering, and assault. Multilevel logistic regression analyses reveal positive and statistically significant albeit substantively modest effects of the district-level sex ratio on all three victimization risks. We also find that higher male-to-female sex ratios are associated with the perception that young unmarried women in the local community are frequently harassed. Household-level indicators of family structure, socioeconomic status, and caste, as well as areal indicators of women's empowerment and collective efficacy, also emerge as significant predictors of self-reported criminal victimization and the perceived harassment of young women. The implications of these findings for India's growing sex ratio imbalance are discussed.

  3. Repeat Syphilis Among Men Who Have Sex With Men in California, 2002–2006: Implications for Syphilis Elimination Efforts

    Science.gov (United States)

    Chew Ng, Rilene A.; Katz, Kenneth A.; Bernstein, Kyle T.; Samuel, Michael C.; Kerndt, Peter R.; Bolan, Gail

    2012-01-01

    Objectives. We examined rates of and risk factors for repeat syphilis infection among men who have sex with men (MSM) in California. Methods. We analyzed 2002 to 2006 California syphilis surveillance system data. Results. During the study period, a mean of 5.9% (range: 4.9%–7.1% per year) of MSM had a repeat primary or secondary (PS) syphilis infection within 2 years of an initial infection. There was no significant increase in the annual proportion of MSM with a repeat syphilis infection (P = .42). In a multivariable model, factors associated with repeat syphilis infection were HIV infection (odds ratio [OR] = 1.65; 95% confidence interval [CI] = 1.14, 2.37), Black race (OR = 1.84; 95% CI = 1.12, 3.04), and 10 or more recent sex partners (OR = 1.99; 95% CI = 1.12, 3.50). Conclusions. Approximately 6% of MSM in California have a repeat PS syphilis infection within 2 years of an initial infection. HIV infection, Black race, and having multiple sex partners are associated with increased odds of repeat infection. Syphilis elimination efforts should include messages about the risk for repeat infection and the importance of follow-up testing. Public health attention to individuals repeatedly infected with syphilis may help reduce local disease burdens. PMID:22095364

  4. Abnormal sex ratios in human populations: causes and consequences.

    Science.gov (United States)

    Hesketh, Therese; Xing, Zhu Wei

    2006-09-05

    In the absence of manipulation, both the sex ratio at birth and the population sex ratio are remarkably constant in human populations. Small alterations do occur naturally; for example, a small excess of male births has been reported to occur during and after war. The tradition of son preference, however, has distorted these natural sex ratios in large parts of Asia and North Africa. This son preference is manifest in sex-selective abortion and in discrimination in care practices for girls, both of which lead to higher female mortality. Differential gender mortality has been a documented problem for decades and led to reports in the early 1990s of 100 million "missing women" across the developing world. Since that time, improved health care and conditions for women have resulted in reductions in female mortality, but these advances have now been offset by a huge increase in the use of sex-selective abortion, which became available in the mid-1980s. Largely as a result of this practice, there are now an estimated 80 million missing females in India and China alone. The large cohorts of "surplus" males now reaching adulthood are predominantly of low socioeconomic class, and concerns have been expressed that their lack of marriageability, and consequent marginalization in society, may lead to antisocial behavior and violence, threatening societal stability and security. Measures to reduce sex selection must include strict enforcement of existing legislation, the ensuring of equal rights for women, and public awareness campaigns about the dangers of gender imbalance.

  5. India’s Distorted Sex Ratio: Dire Consequences for Girls

    Science.gov (United States)

    Roberts, Lisa R.; Montgomery, Susanne B.

    2017-01-01

    Female gender discrimination related to cultural preference for males is a common global problem, especially in Asian countries. Numerous laws intended to prevent discrimination on the basis of gender have been passed in India, yet the distorted female-to-male sex ratio seems to show worsening tendencies. Using detailed, two-year longitudinal chart abstraction data about delivery records of a private mission hospital in rural India, we explored if hospital birth ratio data differed in comparison to regional data, and what demographic and contextual variables may have influenced these outcomes. Using quantitative chart abstraction and qualitative contextual data, study results showed the female-to-male ratio was lower than the reported state ratio at birth. In the context of India’s patriarchal structure, with its strong son preference, women are under tremendous pressure or coerced to access community-based, sex-selective identification and female fetus abortion. Nurses may be key to turning the tide. PMID:28286369

  6. India's Distorted Sex Ratio: Dire Consequences for Girls.

    Science.gov (United States)

    Roberts, Lisa R; Montgomery, Susanne B

    2016-01-01

    Female gender discrimination related to cultural preference for males is a common global problem, especially in Asian countries. Numerous laws intended to prevent discrimination on the basis of gender have been passed in India, yet the distorted female-to-male sex ratio seems to show worsening tendencies. Using detailed, two-year longitudinal chart abstraction data about delivery records of a private mission hospital in rural India, we explored if hospital birth ratio data differed in comparison to regional data, and what demographic and contextual variables may have influenced these outcomes. Using quantitative chart abstraction and qualitative contextual data, study results showed the female-to-male ratio was lower than the reported state ratio at birth. In the context of India's patriarchal structure, with its strong son preference, women are under tremendous pressure or coerced to access community-based, sex-selective identification and female fetus abortion. Nurses may be key to turning the tide.

  7. THE ENIGMA OF ETHIOPIAN SEX RATIOS AT BIRTH.

    Science.gov (United States)

    Garenne, Michel

    2017-09-01

    This study analysed sex ratios at birth (defined as the number of male births per 100 female births) using data on children ever-born from three censuses conducted in Ethiopia in 1984, 1994 and 2007. The results showed very high values by any standard, with an average of 108.4 for a sample of some 8.2 million births, with somewhat lower values in urban areas. Analysis of socioeconomic correlates revealed that the sex ratio varied very much by household wealth, from about 110 for very poor women to about 102 for wealthier women. The high value of the sex ratio at birth in Ethiopia could be explained by poverty, used as a proxy for poor nutritional status. In multivariate analysis, the effects of living in urban areas and of maternal education were less important than household wealth. Among the many ethno-linguistic groups, the Nilotic family had higher sex ratios than other groups. The results were confirmed using data from DHS surveys conducted in the country, and by the analysis of children still living at time of census.

  8. Kin discrimination and sex ratios in a parasitoid wasp

    NARCIS (Netherlands)

    Reece, S.E.; Shuker, D.M.; Pen, I.R.; Duncan, A.B.; Choudhary, A.; Batchelor, C.M.; West, S.A.

    Sex ratio theory provides a clear and simple way to test if nonsocial haplodiploid wasps can discriminate between kin and nonkin. Specifically, if females can discriminate siblings from nonrelatives, then they are expected to produce a higher proportion of daughters if they mate with a sibling. This

  9. Sex ratio of lambs born from assisted reproductive technologies ...

    African Journals Online (AJOL)

    The objective of the present study was to investigate sex ratio of offspring resulting from superstimulated donors from two different breeds and artificially inseminated ewes from three different breeds. Romanov (n = 5) and Charollais (n = 6) (2 - 7 years of age) donors were superovulated using FSH-p with 400 mg ...

  10. Association of secondary sex ratio with smoking and parity.

    Science.gov (United States)

    Beratis, Nicholas G; Asimacopoulou, Aspasia; Varvarigou, Anastasia

    2008-03-01

    To assess the sex ratio in offspring of smoking and nonsmoking mothers in relationship to parity. Prospective study. University hospital. The authors studied 2,108 term singleton neonates born between 1993 and 2002, 665 from smoking mothers and 1,443 from nonsmoking mothers. A prospective recording of maternal age, parity and smoking status, and gender of neonates delivered over a 10-year period. Secondary sex ratio in regard to maternal smoking and parity. The offspring sex ratio in the total sample studied was 1.09; in the offspring of smoking and nonsmoking mothers, it was 1.26 and 1.03, respectively, a statistically significant difference. In the offspring of smoking women who had parity 1, 2, and >or=3, it was 1.47, 1.35, and 0.92, whereas in those of nonsmoking women, it was 1.04, 1.00, and 1.03, respectively (the differences of the parity 1 and 2 groups between the offspring of smoking and nonsmoking mothers were statistically significant). Logistic regression analysis showed that the possibility of a boy being delivered by a mother who smoked was significantly greater in primiparous women than in women who had parity >or=3, independent of the maternal age. Conversely, parity did not affect significantly the sex ratio in the offspring of nonsmoking women. The findings suggest that among women who smoked, significantly more male than female offspring are born from primiparous women, whereas women who had parity >or=3 gave birth to more female offspring; biparous women give birth to significantly more male offspring, but the offspring sex ratio declined with the number of cigarettes when the mothers smoked >or=10 cigarettes per day.

  11. [The sex ratio at birth: a retrospective review and commentary].

    Science.gov (United States)

    Aubenque, M

    1989-01-01

    Trends in the sex ratio are examined, and the possible effect of new biotechnologies on sex preselection is discussed. "We recall that this ratio is very stable, around 105 males for 100 females (live births). However, in France, a slight decreasing trend during the 19th century can be observed (from 107 to 104). At the present time this ratio seems to be maintained at a level of 105.3. The great demographic perturbations, particularly caused by wars, have been marked by a slight but notable increase in the indicator (106) when natality rises again after a deep depression. The variations, always small, of this indicator are more dependent on the male than on female natality, for reasons that are unclear." A comment by Paul Damiani is included (pp. 99-102). (SUMMARY IN ENG) excerpt

  12. Adult sex ratio variation: implications for breeding system evolution.

    Science.gov (United States)

    Székely, T; Weissing, F J; Komdeur, J

    2014-08-01

    Adult sex ratio (ASR) exhibits immense variation in nature, although neither the causes nor the implications of this variation are fully understood. According to theory, the ASR is expected to influence sex roles and breeding systems, as the rarer sex in the population has more potential partners to mate with than the more common sex. Changes in mate choice, mating systems and parental care suggest that the ASR does influence breeding behaviour, although there is a need for more tests, especially experimental ones. In the context of breeding system evolution, the focus is currently on operational sex ratios (OSRs). We argue that the ASR plays a role of similar importance and urge researchers to study the ASR and the OSR side by side. Finally, we plead for a dynamic view of breeding system evolution with feedbacks between mating, parenting, OSR and ASR on both ecological and evolutionary time scales. © 2014 The Authors. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.

  13. Sex Ratio Bias Leads to the Evolution of Sex Role Reversal in Honey Locust Beetles.

    Science.gov (United States)

    Fritzsche, Karoline; Booksmythe, Isobel; Arnqvist, Göran

    2016-09-26

    The reversal of conventional sex roles was enigmatic to Darwin, who suggested that it may evolve when sex ratios are female biased [1]. Here we present direct evidence confirming Darwin's hypothesis. We investigated mating system evolution in a sex-role-reversed beetle (Megabruchidius dorsalis) using experimental evolution under manipulated sex ratios and food regimes. In female-biased populations, where reproductive competition among females was intensified, females evolved to be more attractive and the sex roles became more reversed. Interestingly, female-specific mating behavior evolved more rapidly than male-specific mating behavior. We show that sexual selection due to reproductive competition can be strong in females and can target much the same traits as in males of species with conventional mating systems. Our study highlights two central points: the role of ecology in directing sexual selection and the role that females play in mating system evolution. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Going All In: Unfavorable Sex Ratios Attenuate Choice Diversification.

    Science.gov (United States)

    Ackerman, Joshua M; Maner, Jon K; Carpenter, Stephanie M

    2016-06-01

    When faced with risky decisions, people typically choose to diversify their choices by allocating resources across a variety of options and thus avoid putting "all their eggs in one basket." The current research revealed that this tendency is reversed when people face an important cue to mating-related risk: skew in the operational sex ratio, or the ratio of men to women in the local environment. Counter to the typical strategy of choice diversification, findings from four studies demonstrated that the presence of romantically unfavorable sex ratios (those featuring more same-sex than opposite-sex individuals) led heterosexual people to diversify financial resources less and instead concentrate investment in high-risk/high-return options when making lottery, stock-pool, retirement-account, and research-funding decisions. These studies shed light on a key process by which people manage risks to mating success implied by unfavorable interpersonal environments. These choice patterns have important implications for mating behavior as well as other everyday forms of decision making. © The Author(s) 2016.

  15. Recent increase in sex ratio at birth in Viet Nam.

    Directory of Open Access Journals (Sweden)

    Christophe Z Guilmoto

    Full Text Available INTRODUCTION: Since the 1980s, sex ratio at birth (male births per 100 female births has increased in many Asian countries as a result of selective abortions, but to date there has been no such evidence for Viet Nam. Our aim in this paper is to ascertain the situation with respect to sex ratio at birth in Viet Nam over the past five years. MATERIALS AND METHODS: Original data were obtained from sample population surveys in Viet Nam recording annual birth rates since 2000 of about 450,000 women, as well as from two successive birth surveys conducted for the first time in 2007 (1.1 million births. The annual population surveys include specific information on birth history and mothers' characteristics to be used for the analysis of trends and differentials in sex ratio at birth. RESULTS AND DISCUSSION: Birth history statistics indicate that the SRB in Viet Nam has recorded a steady growth since 2001. Starting from a level probably close to the biological standard of 105, the SRB reached 108 in 2005 and 112 in 2006, a value significantly above the normal level. An independent confirmation of these results comes from the surveys of births in health facilities which yielded a SRB of 110 in 2006-07. High SRB is linked to various factors such as access to modern health care, number of prenatal visits, level of higher education and employment status, young age, province of residence and prenatal sex determination. These results suggest that prenatal sex determination followed by selective abortion has recently become more common in Viet Nam. This recent trend is a consequence of various factors such as preference for sons, declining fertility, easy access to abortion, economic development as well as the increased availability of ultrasonography facilities.

  16. Recent increase in sex ratio at birth in Viet Nam.

    Science.gov (United States)

    Guilmoto, Christophe Z; Hoàng, Xuyên; Van, Toan Ngo

    2009-01-01

    Since the 1980s, sex ratio at birth (male births per 100 female births) has increased in many Asian countries as a result of selective abortions, but to date there has been no such evidence for Viet Nam. Our aim in this paper is to ascertain the situation with respect to sex ratio at birth in Viet Nam over the past five years. Original data were obtained from sample population surveys in Viet Nam recording annual birth rates since 2000 of about 450,000 women, as well as from two successive birth surveys conducted for the first time in 2007 (1.1 million births). The annual population surveys include specific information on birth history and mothers' characteristics to be used for the analysis of trends and differentials in sex ratio at birth. Birth history statistics indicate that the SRB in Viet Nam has recorded a steady growth since 2001. Starting from a level probably close to the biological standard of 105, the SRB reached 108 in 2005 and 112 in 2006, a value significantly above the normal level. An independent confirmation of these results comes from the surveys of births in health facilities which yielded a SRB of 110 in 2006-07. High SRB is linked to various factors such as access to modern health care, number of prenatal visits, level of higher education and employment status, young age, province of residence and prenatal sex determination. These results suggest that prenatal sex determination followed by selective abortion has recently become more common in Viet Nam. This recent trend is a consequence of various factors such as preference for sons, declining fertility, easy access to abortion, economic development as well as the increased availability of ultrasonography facilities.

  17. Maternal Eating Disorders Influence Sex Ratio at Birth

    OpenAIRE

    Bulik, Cynthia M; Von Holle, Ann; Gendall, Kelly; Kveim Lie, Kari; Hoffman, Elizabeth; Mo, Xiaofei; Torgersen, Leila; Reichborn-Kjennerud, Ted

    2008-01-01

    We explored sex ratio at birth, defined as the proportion of male live births, in women with anorexia nervosa, bulimia nervosa, binge eating disorder, and eating disorders not otherwise specified-purging type (EDNOS-P) relative to a referent group in a large population based sample of 38,340 pregnant women in Norway. Poisson regressions were adjusted for mother’s age, pre-pregnancy BMI, lifetime smoking status, maternal education, income, marital status, gestational age, and parity. Lower pro...

  18. Socioeconomic status influences sex ratios in a Chinese rural population.

    Science.gov (United States)

    Luo, Liqun; Ding, Rui; Gao, Xiali; Sun, Jingjing; Zhao, Wei

    2017-01-01

    According to the logic of the Trivers-Willard hypothesis, in a human population, if socioeconomic status is transmitted across generations to some extent, and if sons of high-status parents tend to have higher reproductive success than daughters, while daughters of low-status parents tend to have higher reproductive success than sons, then we should expect that offspring sex ratio is positively associated with socioeconomic status. This study examines whether the assumptions and prediction of this hypothesis apply to a rural population in northern China. Results show that (1) current family socioeconomic status is positively related to family head's father's socioeconomic status in around 1950, (2) low-status family heads have more grandchildren through their daughters than their sons, whereas high- or middle-status family heads have more grandchildren through sons, and (3) as family heads' status increases, they tend to produce a higher offspring sex ratio. Therefore, the assumptions and prediction of the hypothesis are met in the study population. These results are discussed in reference to past studies on sex ratio manipulation among humans.

  19. Population sex ratios: another consideration in the reintroduction - reinforcement debate?

    Directory of Open Access Journals (Sweden)

    Sergio A Lambertucci

    Full Text Available Reintroduction or reinforcement (RorR of wild populations is a common conservation strategy. Many conservation projects involve the release of individuals of poorly studied species. This may lead to inefficient results or negative impacts on the conservation efforts. Here, we provide new insights into the conservation implications and potential consequences of a skew in the sex ratio of released birds and of the number of birds supplemented for the demography of a long-lived dimorphic bird species, the Andean condor (Vulturgryphus. We demonstrate that a RorR conservation program may be less effective in conserving a species if the sex ratios of the releases and the recipient populations are not considered. We also show that releases can reduce population declines but only if carried out over long periods (i.e., several decades. This can mean high costs for release programs and the added challenge of maintaining programs over time. If RorR programs are to be implemented, bearing in mind the importance of properly assessing their effectiveness, we urge conservation researchers and managers to consider the implications of sex ratio biases for wild populations, and particularly for dimorphic species with sexually despotic behaviour.

  20. Preconception maternal polychlorinated biphenyl concentrations and the secondary sex ratio

    International Nuclear Information System (INIS)

    Taylor, Kira C.; Jackson, Leila W.; Lynch, Courtney D.; Kostyniak, Paul J.; Buck Louis, Germaine M.

    2007-01-01

    The secondary sex ratio is the ratio of male to female live births and historically has ranged from 102 to 106 males to 100 females. Temporal declines have been reported in many countries prompting authors to hypothesize an environmental etiology. Blood specimens were obtained from 99 women aged 24-34 prior to attempting pregnancy and quantified for 76 polychlorinated biphenyl (PCB) congeners using dual column gas chromatography with electron capture detection. Women were prospectively followed until pregnancy or 12 cycles of trying. The odds of a male birth for three PCB groupings (total, estrogenic, anti-estrogenic) controlling for maternal characteristics were estimated using logistic regression. Among the 50 women with live births and PCB data, 26 female and 24 male infants were born (ratio 0.92). After adjusting for age and body mass index, odds of a male birth were elevated among women in the second (OR=1.29) and third (OR=1.48) tertiles of estrogenic PCBs; odds (OR=0.70) were reduced among women in the highest tertile of anti-estrogenic PCBs. All confidence intervals included one. The direction of the odds ratios in this preliminary study varied by PCB groupings, supporting the need to study specific PCB patterns when assessing environmental influences on the secondary sex ratio

  1. The effect of sex on the repeatability of evolution in different environments.

    Science.gov (United States)

    Lachapelle, Josianne; Colegrave, Nick

    2017-04-01

    The adaptive function of sex has been extensively studied, while less consideration has been given to the potential downstream consequences of sex on evolution. Here, we investigate one such potential consequence, the effect of sex on the repeatability of evolution. By affecting the repeatability of evolution, sex could have important implications for biodiversity, and for our ability to make predictions about the outcome of environmental change. We allowed asexual and sexual populations of Chlamydomonas reinhardtii to evolve in novel environments and monitored both their change in fitness and variance in fitness after evolution. Sex affected the repeatability of evolution by changing the importance of the effect of selection, chance, and ancestral constraints on the outcome of the evolutionary process. In particular, the effects of sex were highly dependent on the initial genetic composition of the population and on the environment. Given the lack of a consistent effect of sex on repeatability across the environments used here, further studies to dissect in more detail the underlying reasons for these differences as well as studies in additional environments are required if we are to have a general understanding of the effects of sex on the repeatability of evolution. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  2. Sex ratio at birth in India, its relation to birth order, sex of previous children and use of indigenous medicine.

    Directory of Open Access Journals (Sweden)

    Samiksha Manchanda

    Full Text Available OBJECTIVE: Sex-ratio at birth in families with previous girls is worse than those with a boy. Our aim was to prospectively study in a large maternal and child unit sex-ratio against previous birth sex and use of traditional medicines for sex selection. MAIN OUTCOME MEASURES: Sex-ratio among mothers in families with a previous girl and in those with a previous boy, prevalence of indigenous medicine use and sex-ratio in those using medicines for sex selection. RESULTS: Overall there were 806 girls to 1000 boys. The sex-ratio was 720:1000 if there was one previous girl and 178:1000 if there were two previous girls. In second children of families with a previous boy 1017 girls were born per 1000 boys. Sex-ratio in those with one previous girl, who were taking traditional medicines for sex selection, was 928:1000. CONCLUSION: Evidence from the second children clearly shows the sex-ratio is being manipulated by human interventions. More mothers with previous girls tend to use traditional medicines for sex selection, in their subsequent pregnancies. Those taking such medication do not seem to be helped according to expectations. They seem to rely on this method and so are less likely use more definitive methods like sex selective abortions. This is the first such prospective investigation of sex ratio in second children looked at against the sex of previous children. More studies are needed to confirm the findings.

  3. Sex, sex-ratios, and the dynamics of pelagic copepod populations

    DEFF Research Database (Denmark)

    Kiørboe, Thomas

    2006-01-01

    equal adult sex ratios in field populations. Winter population densities are orders of magnitude less than the critical population density required for population persistence, but populations survive winter seasons as resting eggs in the sediment. Population growth in these species is potentially high...... because they have on average a factor of 2 higher egg production rates than other pelagic copepods. Secondly, other copepods require only one mating to stay fertile, and populations of these species have strongly female-skewed adult sex-ratios in field populations. Resting eggs have not been described...

  4. Could changes in reported sex ratios at birth during China's 1958-1961 famine support the adaptive sex ratio adjustment hypothesis?

    Directory of Open Access Journals (Sweden)

    Anna Reimondos

    2013-10-01

    Full Text Available Background: The adaptive sex ratio adjustment hypothesis suggests that when mothers are in poor conditions the sex ratio of their offspring will be biased towards females. Major famines provide opportunities for testing this hypothesis because they lead to the widespread deterioration of living conditions in the affected population. Objective: This study examines changes in sex ratio at birth before, during, and after China's 1958-1961 famine, to see whether they provide any support for the adaptive sex ratio adjustment hypothesis. Methods: We use descriptive statistics to analyse data collected by both China's 1982 and 1988 fertility sample surveys and examine changes in sex ratio at birth in recent history. In addition, we examine the effectiveness of using different methods to model changes in sex ratio at birth and compare their differences. Results: During China's 1958-1961 famine, reported sex ratio at birth remained notably higher than that observed in most countries in the world. The timing of the decline in sex ratio at birth did not coincide with the timing of the famine. After the famine, although living conditions were considerably improved, the sex ratio at birth was not higher but lower than that recorded during the famine. Conclusions: The analysis of the data collected by the two fertility surveys has found no evidence that changes in sex ratio at birth during China's 1958-1961 famine and the post-famine period supported the adaptive sex ratio adjustment hypothesis.

  5. The effect of climate fluctuation on chimpanzee birth sex ratio.

    Directory of Open Access Journals (Sweden)

    Hjalmar S Kühl

    Full Text Available Climate and weather conditions, such as the North Atlantic Oscillation, precipitation and temperature influence the birth sex ratio (BSR of various higher latitude species, including deer, elephant seals or northern human populations. Although, tropical regions show only little variation in temperature, climate and weather conditions can fluctuate with consequences for phenology and food resource availability. Here, we evaluate, whether the BSR of chimpanzees, inhabiting African tropical forests, is affected by climate fluctuations as well. Additionally, we evaluate, if variation in consumption of a key food resource with high nutritional value, Coula edulis nuts, is linked to both climate fluctuations and variation in BSR. We use long-term data from two study groups located in Taï National Park, Côte d'Ivoire to assess the influence of local weather conditions and the global climate driver El Niño Southern Oscillation (ENSO on offspring sex. Côte d'Ivoire has experienced considerable climate variation over the last decades, with increasing temperature and declining precipitation. For both groups we find very similar time windows around the month of conception, in which offspring sex is well predicted by ENSO, with more males following low ENSO values, corresponding to periods of high rainfall. Furthermore, we find that the time spent cracking and feeding on Coula nuts is strongly influenced by climate conditions. Although, some of our analysis suggest that a higher proportion of males is born after periods with higher nut consumption frequency, we cannot conclude decisively at this point that nut consumption may influence shifts in BSR. All results combined suggest that also chimpanzees may experience climate related shifts in offspring sex ratios as response to climate fluctuation.

  6. The evolution of sex roles in birds is related to adult sex ratio.

    Science.gov (United States)

    Liker, András; Freckleton, Robert P; Székely, Tamás

    2013-01-01

    Sex-role reversal represents a formidable challenge for evolutionary biologists, since it is not clear which ecological, life-history or social factors facilitated conventional sex roles (female care and male-male competition for mates) to be reversed (male care and female-female competition). Classic theories suggested ecological or life-history predictors of role reversal, but most studies failed to support these hypotheses. Recent theory however predicts that sex-role reversal should be driven by male-biased adult sex ratio (ASR). Here we test this prediction for the first time using phylogenetic comparative analyses. Consistent with theory, both mating system and parental care are strongly related to ASR in shorebirds: conventional sex roles are exhibited by species with female-biased ASR, whereas sex-role reversal is associated with male-biased ASR. These results suggest that social environment has a strong influence on breeding systems and therefore revealing the causes of ASR variation in wild populations is essential for understanding sex role evolution.

  7. Genetic architecture of sex determination in fish: Applications to sex ratio control in aquaculture

    Directory of Open Access Journals (Sweden)

    Paulino eMartínez

    2014-09-01

    Full Text Available Controlling the sex ratio is essential in finfish farming. A balanced sex ratio is usually good for broodstock management, since it enables to develop appropriate breeding schemes. However, in some species the production of monosex populations is desirable because the existence of sexual dimorphism, primarily in growth or first time of sexual maturation, but also in color or shape, can render one sex more valuable. The knowledge of the genetic architecture of sex determination (SD is convenient for controlling sex ratio and for the implementation of breeding programs. Unlike mammals and birds, which show highly conserved master genes that control a conserved genetic network responsible for gonad differentiation (GD, a huge diversity of SD mechanisms has been reported in fish. Despite theory predictions, more than one gene is in many cases involved in fish SD and genetic differences have been observed in the GD network. Environmental factors also play a relevant role and epigenetic mechanisms are becoming increasingly recognized for the establishment and maintenance of the GD pathways. Although major genetic factors are frequently involved in fish SD, these observations strongly suggest that SD in this group resembles a complex trait. Accordingly, the application of quantitative genetics combined with genomic tools is desirable to address its study and in fact, when applied, it has frequently demonstrated a multigene trait interacting with environmental factors in model and cultured fish species. This scenario has notable implications for aquaculture and, depending upon the species, from chromosome manipulation or environmental control techniques up to classical selection or marker assisted selection programs, are being applied. In this review, we selected four relevant species or fish groups to illustrate this diversity and hence the technologies that can be used by the industry for the control of sex ratio: turbot and European sea bass, two

  8. Human semen quality and the secondary sex ratio.

    Science.gov (United States)

    Bae, Jisuk; Kim, Sungduk; Chen, Zhen; Eisenberg, Michael L; Buck Louis, Germaine M

    2017-01-01

    The aim of this study was to evaluate the association between semen quality and the secondary sex ratio (SSR), defined as the ratio of male to female live births. Our study cohort comprised 227 male partners who were enrolled prior to conception in Michigan and Texas between 2005 and 2009, and prospectively followed through delivery of a singleton birth. The male partners provided a baseline and a follow-up semen sample a month apart. Semen analysis was conducted to assess 27 parameters including five general characteristics, six sperm head measures, 14 morphology measures, and two sperm chromatin stability assay measures. Modified Poisson regression models with a robust error variance were used to estimate the relative risk (RR) and 95% confidence interval (95% CI) of a male birth for each semen parameter, after adjusting for potential confounders. Of the 27 semen parameters, only the percentage of bicephalic sperm was significantly associated with the SSR (2 nd vs 1 st quartile, RR, 0.65, 95% CI, 0.45-0.95, P = 0.03; 4 th vs 1 st quartile, RR, 0.61, 95% CI, 0.38-1.00, P semen quality is associated with offspring sex determination.

  9. Sex ratio variation in the bumblebee Bombus terrestris

    DEFF Research Database (Denmark)

    Duchateau, Marie José; Velthuis, Hayo H. W.; Boomsma, Jacobus Jan

    2004-01-01

    Bombus terrestris, bumblebees, colony development, queen control, reproductive strategies, sex allocation......Bombus terrestris, bumblebees, colony development, queen control, reproductive strategies, sex allocation...

  10. Sex allocation and secondary sex ratio in Cuban boa ( Chilabothrus angulifer): mother's body size affects the ratio between sons and daughters

    Science.gov (United States)

    Frynta, Daniel; Vejvodová, Tereza; Šimková, Olga

    2016-06-01

    Secondary sex ratios of animals with genetically determined sex may considerably deviate from equality. These deviations may be attributed to several proximate and ultimate factors. Sex ratio theory explains some of them as strategic decisions of mothers improving their fitness by selective investment in sons or daughters, e.g. local resource competition hypothesis (LRC) suggests that philopatric females tend to produce litters with male-biased sex ratios to avoid future competition with their daughters. Until now, only little attention has been paid to examine predictions of sex ratio theory in snakes possessing genetic sex determination and exhibiting large variance in allocation of maternal investment. Cuban boa is an endemic viviparous snake producing large-bodied newborns (˜200 g). Extremely high maternal investment in each offspring increases importance of sex allocation. In a captive colony, we collected breeding records of 42 mothers, 62 litters and 306 newborns and examined secondary sex ratios (SR) and sexual size dimorphism (SSD) of newborns. None of the examined morphometric traits of neonates appeared sexually dimorphic. The sex ratio was slightly male biased (174 males versus 132 females) and litter sex ratio significantly decreased with female snout-vent length. We interpret this relationship as an additional support for LRC as competition between mothers and daughters increases with similarity of body sizes between competing snakes.

  11. Selective interactions among Rh, ABO, and sex ratio of newborns.

    Science.gov (United States)

    Valenzuela, C Y; Walton, R

    1985-01-01

    The hypothesis that the Rh and ABO blood systems behave like the HLA system in relation to mother-conception tolerance-rejection mechanisms was tested in 25,501 mother-infant pairs. According to this hypothesis, heterozygotes carrying a paternal gene that is not present in their mothers should be better tolerated than homozygotes. Significantly more BO infants born to AO mothers. AO infants born to BO mothers, Rh(+) heterozygotes born to Rh(-) mothers, and less significantly AO infants born to OO mothers confirm the hypothesis. Fewer homozygotes occurred in Rh(-) infants born to Rh(+) mothers and in O infants born to non-O mothers. Deviations from the Hardy-Weinberg equilibrium found in the ABO system were modified by the Rh and sex of the infant. These data strongly support the hypothesis that at least two feto-maternal systems influence the destiny of pregnancies: the classical known incompatibility system which operates late in pregnancy and a new one which is based on the induction of maternal tolerance early in pregnancy: maternal tolerance seems to be better elicited by heterozygous eggs or embryos carrying a gene not present in the mother. The data also support the hypothesis that the sex ratio is influenced by feto-maternal tolerance-rejection mechanisms associated with the ABO and Rh systems.

  12. A study to review sex ratio at birth and analyze preferences for the sex of the unborn.

    Science.gov (United States)

    Warade, Yugali; Balsarkar, Geetha; Bandekar, Pooja

    2014-02-01

    (1) To study the status of sex ratio at birth with increasing birth order, (2) To ascertain the relationship of declining sex ratio with respect to socio demographic factors. (3) To study outlook of patient towards sex preference, willingness to determine sex of the fetus, wish to terminate the pregnancy in case of unwanted sex of the baby. This is the retrospective study done in the Department of Obstetrics and Gynaecology, Nowrosjee Wadia Maternity Hospital, Parel, Mumbai. The data was collected from the records maintained in Medical Record Department from January 2007 to December 2012 and were studied to determine the sex ratio as well as its relationship with the increasing parity. 95 % confidence interval for the sex ratios was calculated. Average sex ratio of 6 years was 908 females per 1,000 males. Sex ratio was 972 females per 1,000 males in primi para, which decreased to 879 females per 1,000 males in second para, further reduced to 784 females per 1,000 males in third para and 864 females per 1,000 males in fourth para. The 'sex ratio at birth', defined as the number of girls born for every 1,000 boys born, is a more accurate and refined indicator of the extent of prenatal sex selection.

  13. Strong but variable associations between social dominance and clutch sex ratio in a colonial corvid

    NARCIS (Netherlands)

    Salomons, H. M.; Dijkstra, C.; Verhulst, S.

    2008-01-01

    We studied primary sex ratio of clutches in relation to social dominance for 6 years in a colony of free-living jackdaws, a small corvid. Social dominance was strongly associated with clutch sex ratio, with the difference in clutch sex ratio between the most and least dominant pairs being 30-40%. To

  14. Density-dependent sex ratio and sex-specific preference for host traits in parasitic bat flies.

    Science.gov (United States)

    Szentiványi, Tamara; Vincze, Orsolya; Estók, Péter

    2017-08-29

    Deviation of sex ratios from unity in wild animal populations has recently been demonstrated to be far more prevalent than previously thought. Ectoparasites are prominent examples of this bias, given that their sex ratios vary from strongly female- to strongly male-biased both among hosts and at the metapopulation level. To date our knowledge is very limited on how and why these biased sex ratios develop. It was suggested that sex ratio and sex-specific aggregation of ectoparasites might be shaped by the ecology, behaviour and physiology of both hosts and their parasites. Here we investigate a highly specialised, hematophagous bat fly species with strong potential to move between hosts, arguably limited inbreeding effects, off-host developmental stages and extended parental care. We collected a total of 796 Nycteribia kolenatii bat flies from 147 individual bats using fumigation and subsequently determined their sex. We report a balanced sex ratio at the metapopulation level and a highly variable sex ratio among infrapopulations ranging from 100% male to 100% female. We show that infrapopulation sex ratio is not random and is highly correlated with infrapopulation size. Sex ratio is highly male biased in small and highly female biased in large infrapopulations. We show that this pattern is most probably the result of sex-specific preference in bat flies for host traits, most likely combined with a higher mobility of males. We demonstrate that female bat flies exert a strong preference for high host body condition and female hosts, while the distribution of males is more even. Our results suggest that locally biased sex ratios can develop due to sex-specific habitat preference of parasites. Moreover, it is apparent that the sex of both hosts and parasites need to be accounted for when a better understanding of host-parasite systems is targeted.

  15. Sexual orientation, handedness, sex ratio and fetomaternal tolerance-rejection

    Directory of Open Access Journals (Sweden)

    Carlos Y Valenzuela

    2010-01-01

    Full Text Available Fraternal birth order (FBO appears as a prenatal cause of 15% of homosexual males (gays through mnemonic maternal anti-male factors. Non-right-handed men seem to be protected from homosexuality. Four hypotheses are proposed: (1 androgenic factors of non-right-handedness neutralize anti-male factors; (2 non-right-handedness and homosexuality are lethal or produce mental impairment; (3 non-right-handed male embryos are insensitive to anti-male factors; (4 mothers of non-right-handed fetuses do not produce anti-male factors. Studies of the sex ratio (SR of older and younger siblings show: (1 a significant heterogeneity in the SR of siblings of right or non-right handed heterosexual men and women; (2 lesbians are born among siblings with high SR; (3 siblings of right-handed gays show a higher SR than non-right-handed gays that present a low SR. Based on our discovery of maternal tolerance-rejection processes, associated with genetic systems (ABO, Rh, where zygotes or embryos different from their mother induce better pregnancy and maternal tolerance than do those that share antigens with their mothers, I propose a new explanation for sexual relationships, sexual orientation, handedness and sibling SR. Lesbian embryos could induce tolerance from mothers with anti-female factors. Non-right-handedness could induce maternal tolerance, or change the maternal compatibility of "gay" embryos. Alternatively, gay embryos could be poor inducers of maternal tolerance towards male traits.

  16. Sexual orientation, handedness, sex ratio and fetomaternal tolerance-rejection.

    Science.gov (United States)

    Valenzuela, Carlos Y

    2010-01-01

    Fraternal birth order (FBO) appears as a prenatal cause of 15% of homosexual males (gays) through mnemonic maternal anti-male factors. Non-right-handed men seem to be protected from homosexuality. Four hypotheses are proposed: (1) androgenic factors of non-right-handedness neutralize anti-male factors; (2) non-right-handedness and homosexuality are lethal or produce mental impairment; (3) non-right-handed male embryos are insensitive to anti-male factors; (4) mothers of non-right-handed fetuses do not produce anti-male factors. Studies of the sex ratio (SR) of older and younger siblings show: (1) a significant heterogeneity in the SR of siblings of right or non-right handed heterosexual men and women; (2) lesbians are born among siblings with high SR; (3) siblings of right-handed gays show a higher SR than non-right-handed gays that present a low SR. Based on our discovery of maternal tolerance-rejection processes, associated with genetic systems (ABO, Rh), where zygotes or embryos different from their mother induce better pregnancy and maternal tolerance than do those that share antigens with their mothers, I propose a new explanation for sexual relationships, sexual orientation, handedness and sibling SR. Lesbian embryos could induce tolerance from mothers with anti-female factors. Non-right-handedness could induce maternal tolerance, or change the maternal compatibility of "gay" embryos. Alternatively, gay embryos could be poor inducers of maternal tolerance towards male traits.

  17. Manipulation of primary sex ratio in birds : Lessons from the Homing Pigeon (Columba livia domestica)

    NARCIS (Netherlands)

    Goerlich-Jansson, Vivian C.; Muller, Martina S.; Groothuis, Ton G. G.

    2013-01-01

    Across various animal taxa not only the secondary sex ratio but also the primary sex ratio (at conception) shows significant deviations from the expected equal proportions of sons and daughters. Birds are especially intriguing to study this phenomenon as avian females are the heterogametic sex (ZW);

  18. Relationship Formation and Stability in Emerging Adulthood: Do Sex Ratios Matter?

    Science.gov (United States)

    Warner, Tara D.; Manning, Wendy D.; Giordano, Peggy C.; Longmore, Monica A.

    2011-01-01

    Research links sex ratios with the likelihood of marriage and divorce. However, whether sex ratios similarly influence precursors to marriage (transitions in and out of dating or cohabiting relationships) is unknown. Utilizing data from the Toledo Adolescent Relationships Study and the 2000 U.S. Census, this study assesses whether sex ratios…

  19. An unstable social environment affects sex ratio in guinea pigs : an adaptive maternal effect?

    NARCIS (Netherlands)

    Kemme, Kristina; Kaiser, Sylvia; von Engelhardt, Nikolaus; Wewers, Dirk; Groothuis, Ton; Sachser, Norbert

    2009-01-01

    Evolutionary theory suggests that offspring sex should be adjusted to environmental conditions in order to maximize future reproductive success. In several animal taxa environmental factors indeed affect the secondary sex ratio. In humans, changes in the sex ratio at birth have been associated with

  20. Working Late: Do Workplace Sex Ratios Affect Partnership Formation and Dissolution?

    Science.gov (United States)

    Svarer, Michael

    2007-01-01

    In this paper, I analyze the association between workplace sex ratios and partnership formation and dissolution. I find that the risk of dissolution increases with the fraction of coworkers of the opposite sex at both the female and male workplace. On the other hand, workplace sex ratios are not important for the overall transition rate from…

  1. The impact of sex ratio and economic status on local birth rates

    OpenAIRE

    Chipman, A.; Morrison, E.

    2013-01-01

    Human mating and reproductive behaviour can vary depending on various mechanisms, including the local sex ratio. Previous research shows that as sex ratios become female-biased, women from economically deprived areas are less likely to delay reproductive opportunities to wait for a high-investing mate but instead begin their reproductive careers sooner. Here, we show that the local sex ratio also has an impact on female fertility schedules. At young ages, a female-biased ratio is associated w...

  2. A heritable component in sex ratio and caste determination in a Cardiocondyla ant

    Directory of Open Access Journals (Sweden)

    Heinze Jürgen

    2009-10-01

    Full Text Available Abstract Studies on sex ratios in social insects provide among the most compelling evidence for the importance of kin selection in social evolution. The elegant synthesis of Fisher's sex ratio principle and Hamilton's inclusive fitness theory predicts that colony-level sex ratios vary with the colonies' social and genetic structures. Numerous empirical studies in ants, bees, and wasps have corroborated these predictions. However, the evolutionary optimization of sex ratios requires genetic variation, but one fundamental determinant of sex ratios - the propensity of female larvae to develop into young queens or workers ("queen bias" - is thought to be largely controlled by the environment. Evidence for a genetic influence on sex ratio and queen bias is as yet restricted to a few taxa, in particular hybrids. Because of the very short lifetime of their queens, ants of the genus Cardiocondyla are ideal model systems for the study of complete lifetime reproductive success, queen bias, and sex ratios. We found that lifetime sex ratios of the ant Cardiocondyla kagutsuchi have a heritable component. In experimental single-queen colonies, 22 queens from a genetic lineage with a highly female-biased sex ratio produced significantly more female-biased offspring sex ratios than 16 queens from a lineage with a more male-biased sex ratio (median 91.5% vs. 58.5% female sexuals. Sex ratio variation resulted from different likelihood of female larvae developing into sexuals (median 50% vs. 22.6% female sexuals even when uniformly nursed by workers from another colony. Consistent differences in lifetime sex ratios and queen bias among queens of C. kagutsuchi suggest that heritable, genetic or maternal effects strongly affect caste determination. Such variation might provide the basis for adaptive evolution of queen and worker strategies, though it momentarily constrains the power of workers and queens to optimize caste ratios.

  3. A heritable component in sex ratio and caste determination in a Cardiocondyla ant.

    Science.gov (United States)

    Frohschammer, Sabine; Heinze, Jürgen

    2009-10-28

    Studies on sex ratios in social insects provide among the most compelling evidence for the importance of kin selection in social evolution. The elegant synthesis of Fisher's sex ratio principle and Hamilton's inclusive fitness theory predicts that colony-level sex ratios vary with the colonies' social and genetic structures. Numerous empirical studies in ants, bees, and wasps have corroborated these predictions. However, the evolutionary optimization of sex ratios requires genetic variation, but one fundamental determinant of sex ratios - the propensity of female larvae to develop into young queens or workers ("queen bias") - is thought to be largely controlled by the environment. Evidence for a genetic influence on sex ratio and queen bias is as yet restricted to a few taxa, in particular hybrids.Because of the very short lifetime of their queens, ants of the genus Cardiocondyla are ideal model systems for the study of complete lifetime reproductive success, queen bias, and sex ratios. We found that lifetime sex ratios of the ant Cardiocondyla kagutsuchi have a heritable component. In experimental single-queen colonies, 22 queens from a genetic lineage with a highly female-biased sex ratio produced significantly more female-biased offspring sex ratios than 16 queens from a lineage with a more male-biased sex ratio (median 91.5% vs. 58.5% female sexuals). Sex ratio variation resulted from different likelihood of female larvae developing into sexuals (median 50% vs. 22.6% female sexuals) even when uniformly nursed by workers from another colony.Consistent differences in lifetime sex ratios and queen bias among queens of C. kagutsuchi suggest that heritable, genetic or maternal effects strongly affect caste determination. Such variation might provide the basis for adaptive evolution of queen and worker strategies, though it momentarily constrains the power of workers and queens to optimize caste ratios.

  4. Inter-Annual Variability of Fledgling Sex Ratio in King Penguins.

    Science.gov (United States)

    Bordier, Célia; Saraux, Claire; Viblanc, Vincent A; Gachot-Neveu, Hélène; Beaugey, Magali; Le Maho, Yvon; Le Bohec, Céline

    2014-01-01

    As the number of breeding pairs depends on the adult sex ratio in a monogamous species with biparental care, investigating sex-ratio variability in natural populations is essential to understand population dynamics. Using 10 years of data (2000-2009) in a seasonally monogamous seabird, the king penguin (Aptenodytes patagonicus), we investigated the annual sex ratio at fledging, and the potential environmental causes for its variation. Over more than 4000 birds, the annual sex ratio at fledging was highly variable (ranging from 44.4% to 58.3% of males), and on average slightly biased towards males (51.6%). Yearly variation in sex-ratio bias was neither related to density within the colony, nor to global or local oceanographic conditions known to affect both the productivity and accessibility of penguin foraging areas. However, rising sea surface temperature coincided with an increase in fledging sex-ratio variability. Fledging sex ratio was also correlated with difference in body condition between male and female fledglings. When more males were produced in a given year, their body condition was higher (and reciprocally), suggesting that parents might adopt a sex-biased allocation strategy depending on yearly environmental conditions and/or that the effect of environmental parameters on chick condition and survival may be sex-dependent. The initial bias in sex ratio observed at the juvenile stage tended to return to 1∶1 equilibrium upon first breeding attempts, as would be expected from Fisher's classic theory of offspring sex-ratio variation.

  5. Getting past nature as a guide to the human sex ratio.

    Science.gov (United States)

    Murphy, Timothy F

    2013-05-01

    Sex selection of children by pre-conception and post-conception techniques remains morally controversial and even illegal in some jurisdictions. Among other things, some critics fear that sex selection will distort the sex ratio, making opposite-sex relationships more difficult to secure, while other critics worry that sex selection will tilt some nations toward military aggression. The human sex ratio varies depending on how one estimates it; there is certainly no one-to-one correspondence between males and females either at birth or across the human lifespan. Complications about who qualifies as 'male' and 'female' complicate judgments about the ratio even further. Even a judiciously estimated sex ratio does not have, however, the kind of normative status that requires society to refrain from antenatal sex selection. Some societies exhibit lopsided sex ratios as a consequence of social policies and practices, and pragmatic estimates of social needs are a better guide to what the sex ratio should be, as against looking to 'nature'. The natural sex ratio cannot be a sound moral basis for prohibiting parents from selecting the sex of their children, since it ultimately lacks any normative meaning for social choices. © 2011 Blackwell Publishing Ltd.

  6. Maternal condition but not corticosterone is linked to offspring sex ratio in a passerine bird.

    Directory of Open Access Journals (Sweden)

    Lindsay J Henderson

    Full Text Available There is evidence of offspring sex ratio adjustment in a range of species, but the potential mechanisms remain largely unknown. Elevated maternal corticosterone (CORT is associated with factors that can favour brood sex ratio adjustment, such as reduced maternal condition, food availability and partner attractiveness. Therefore, the steroid hormone has been suggested to play a key role in sex ratio manipulation. However, despite correlative and causal evidence CORT is linked to sex ratio manipulation in some avian species, the timing of adjustment varies between studies. Consequently, whether CORT is consistently involved in sex-ratio adjustment, and how the hormone acts as a mechanism for this adjustment remains unclear. Here we measured maternal baseline CORT and body condition in free-living blue tits (Cyanistes caeruleus over three years and related these factors to brood sex ratio and nestling quality. In addition, a non-invasive technique was employed to experimentally elevate maternal CORT during egg laying, and its effects upon sex ratio and nestling quality were measured. We found that maternal CORT was not correlated with brood sex ratio, but mothers with elevated CORT fledged lighter offspring. Also, experimental elevation of maternal CORT did not influence brood sex ratio or nestling quality. In one year, mothers in superior body condition produced male biased broods, and maternal condition was positively correlated with both nestling mass and growth rate in all years. Unlike previous studies maternal condition was not correlated with maternal CORT. This study provides evidence that maternal condition is linked to brood sex ratio manipulation in blue tits. However, maternal baseline CORT may not be the mechanistic link between the maternal condition and sex ratio adjustment. Overall, this study serves to highlight the complexity of sex ratio adjustment in birds and the difficulties associated with identifying sex biasing mechanisms.

  7. The potential pitfalls of studying adult sex ratios at aggregate levels in humans.

    Science.gov (United States)

    Pollet, Thomas V; Stoevenbelt, Andrea H; Kuppens, Toon

    2017-09-19

    Human adult sex ratios have been studied extensively across the biological and social sciences. While several studies have examined adult sex ratio effects in a multilevel perspective, many studies have focused on effects at an aggregated level only. In this paper, we review some key issues relating to such analyses. We address not only nation-level analyses, but also aggregation at lower levels, to investigate whether these issues extend to lower levels of aggregation. We illustrate these issues with novel databases covering a broad range of variables. Specifically, we discuss distributional issues with aggregated measures of adult sex ratio, significance testing, and statistical non-independence when using aggregate data. Firstly, we show that there are severe distributional issues with national adult sex ratio, such as extreme cases. Secondly, we demonstrate that many 'meaningless' variables are significantly correlated with adult sex ratio (e.g. the max. elevation level correlates with sex ratio at US state level). Finally, we re-examine associations between adult sex ratios and teenage fertility and find no robust evidence for an association at the aggregate level. Our review highlights the potential issues of using aggregate data on adult sex ratios to test hypotheses from an evolutionary perspective in humans.This article is part of the themed issue 'Adult sex ratios and reproductive decisions: a critical re-examination of sex differences in human and animal societies'. © 2017 The Author(s).

  8. Neither Biased Sex Ratio nor Spatial Segregation of the Sexes in the Subtropical Dioecious Tree Eurycorymbus cavaleriei (Sapindaceae)

    Institute of Scientific and Technical Information of China (English)

    Pu-xin Gao; Ming Kang; Jing Wang; Qi-gang Ye; Hong-wen Huang

    2009-01-01

    Knowledge of sex ratio and spatial distribution of males and females of dioecious species is both of evolutionary interest and of crucial importance for biological conservation. Eurycorymbus cavaleriei, the only species in the genus Eurycorymbus (Saplndaceae), is a dioecious tree endemic to subtropical montane forest in South China. Sex ratios were investigated in 15 natural populations for the two defined ages (young and old). Spatial distribution of males and females was further studied in six large populations occurring in different habitats (fragmented and continuous). The study revealed a slight trend of malebiased sex ratio in both ages of E. cavaleriei, but sex ratio of most populations (13 out of 15) did not display statistically significant deviation from equality. All of the four significantly male-biased populations in the young class shifted to equality or even female-biased. The Ripley's K analysis of the distribution of males with respect to females suggested that individuals of the opposite sexes were more randomly distributed rather than spatially structured. These results suggest that the male-biased sex ratio in E. cavaleriei may result from the precocity of males and habitat heterogeneity. The sex ratio and the sex spatial distribution pattern are unlikely to constitute a serious threat to the survival of the species.

  9. Hatchling sex ratio and female mating status in the great reed warbler, Acrocephalus arundinaceus (Aves, Passeriformes): further evidence for offspring sex ratio manipulation

    Czech Academy of Sciences Publication Activity Database

    Trnka, A.; Prokop, P.; Kašová, M.; Sobeková, Karolina; Kocian, Ľ.

    2012-01-01

    Roč. 79, č. 2 (2012), s. 212-217 ISSN 1125-0003 Institutional support: RVO:68081766 Keywords : Great reed warbler * sex ratio * social polygyny Subject RIV: EG - Zoology Impact factor: 0.890, year: 2012

  10. Sibling sex ratio of individuals diagnosed with autism spectrum disorder as children

    DEFF Research Database (Denmark)

    Mouridsen, Svend Erik; Rich, Bente; Isager, Torben

    2010-01-01

    AIM: To study the sex ratio (proportion of males) in siblings of individuals diagnosed with autism spectrum disorders (ASDs) as children. METHOD: In the current study, we extended previous studies dealing with the androgen theory of autism and examined sex ratios in the siblings of 326 individuals...... the Danish live-birth sex ratio over the same period (0.514, p=0.001). The sibling sex ratio was not associated with the IQ in the autistic probands. INTERPRETATION: Our findings suggest a potential indirect confirmation of the androgen theory of autism....

  11. Sex ratio in two species of Pegoscapus wasps (Hymenoptera: Agaonidae) that develop in figs: can wasps do mathematics, or play sex ratio games?

    Science.gov (United States)

    Ramírez-Benavides, William; Monge-Nájera, Julián; Chavarría, Juan B

    2009-09-01

    The fig pollinating wasps (Hymenoptera: Agaonidae) have obligate arrhenotoky and a breeding structure that fits local mate competition (LMC). It has been traditionally assumed that LMC organisms adjust the sex ratio by laying a greater proportion of male eggs when there is superparasitism (several foundresses in a host). We tested the assumption with two wasp species, Pegoscapus silvestrii, pollinator of Ficus pertusa and Pegoscapus tonduzi, pollinator of Ficus eximia (= F citrifolia), in the Central Valley of Costa Rica. Total number of wasps and seeds were recorded in individual isolated naturally colonized syconia. There was a constant additive effect between the number of foundresses and the number of males produced in the brood of a syconium, while the number of females decreased. Both wasp species seem to have precise sex ratios and probably lay the male eggs first in the sequence, independently of superparasitism and clutch size: consequently, they have a non-random sex allocation. Each syconium of Ficus pertusa and of F. eximia colonized by one foundress had similar mean numbers of females, males, and seeds. The two species of wasps studied do not seem to adjust the sex ratio when there is superparasitism. Pollinating fig wasp behavior is better explained by those models not assuming that females do mathematical calculations according to other females' sex ratios, size, number of foundresses, genetic constitution, clutch size or environmental conditions inside the syconium. Our results are in agreement with the constant male number hypothesis, not with sex ratio games.

  12. No evidence for selective follicle abortion underlying primary sex ratio adjustment in pigeons

    NARCIS (Netherlands)

    Goerlich, Vivian C.; Dijkstra, Cornelis; Groothuis, Antonius

    Primary sex ratio adjustment in birds has been extensively studied, yet the underlying physiological mechanisms are far from understood. Avian females are the heterogametic sex (ZW), and the future sex of the offspring is determined at chromosome segregation during meiosis I, shortly before the

  13. Pre-ovulation control of hatchling sex ratio in the Seychelles warbler

    NARCIS (Netherlands)

    Komdeur, J; Magrath, MJL; Krackow, S

    2002-01-01

    Females of some bird species have a high degree of control over the sex ratio of their offspring at laying. Although several mechanisms have been put forward to explain how females might control the sex of their eggs, virtually nothing is known. As females are the heterogametic sex in birds,

  14. Manipulation of primary sex ratio in birds: lessons from the homing pigeon (Columba livia domestica).

    Science.gov (United States)

    Goerlich-Jansson, Vivian C; Müller, Martina S; Groothuis, Ton G G

    2013-12-01

    Across various animal taxa not only the secondary sex ratio but also the primary sex ratio (at conception) shows significant deviations from the expected equal proportions of sons and daughters. Birds are especially intriguing to study this phenomenon as avian females are the heterogametic sex (ZW); therefore sex determination might be under direct control of the mother. Avian sex ratios vary in relation to environmental or maternal condition, which can also affect the production of maternal steroids that in turn are involved in reproduction and accumulate in the developing follicle before meiosis. As the proximate mechanisms underlying biased primary sex ratio are largely elusive, we explored how, and to what extent, maternal steroid hormones may be involved in affecting primary or secondary sex ratio in clutches of various species of pigeons. First we demonstrated a clear case of seasonal change in sex ratio in first eggs both in the Rock Pigeon (Columba livia) and in a related species, the Wood Pigeon (Columba palumbus), both producing clutches of two eggs. In the Homing Pigeon (Columba livia domestica), domesticated from the Rock Pigeon, testosterone treatment of breeding females induced a clear male bias, while corticosterone induced a female bias in first eggs and we argue that this is in line with sex allocation theory. We next analyzed treatment effects on follicle formation, yolk mass, and yolk hormones, the latter both pre- and post-ovulatory, in order to test a diversity of potential mechanisms related to both primary and secondary sex ratio manipulation. We conclude that maternal plasma hormone levels may affect several pre-ovulatory mechanisms affecting primary sex ratio, whereas egg hormones are probably involved in secondary sex ratio manipulation only.

  15. Meiotic sex ratio variation in natural populations of Ceratodon purpureus (Ditrichaceae).

    Science.gov (United States)

    Norrell, Tatum E; Jones, Kelly S; Payton, Adam C; McDaniel, Stuart F

    2014-09-01

    Sex ratio variation is a common but often unexplained phenomenon in species across the tree of life. Here we evaluate the hypothesis that meiotic sex ratio variation can contribute to the biased sex ratios found in natural populations of the moss Ceratodon purpureus.• We obtained sporophytes from several populations of C. purpureus from eastern North America. From each sporophyte, we estimated the mean spore viability by germinating replicate samples on agar plates. We estimated the meiotic sex ratio of each sporophyte by inferring the sex of a random sample of germinated spores (mean = 77) using a PCR-RFLP test. We tested for among-sporophyte variation in viability using an ANOVA and for deviations from 1:1 sex ratio using a χ(2)-test and evaluated the relationship between these quantities using a linear regression.• We found among-sporophyte variation in spore viability and meiotic sex ratio, suggesting that genetic variants that contribute to variation in both of these traits segregate within populations of this species. However, we found no relationship between these quantities, suggesting that factors other than sex ratio distorters contribute to variation in spore viability within populations.• These results demonstrate that sex ratio distortion may partially explain the population sex ratio variation seen in C. purpureus, but more generally that genetic conflict over meiotic segregation may contribute to fitness variation in this species. Overall, this study lays the groundwork for future studies on the genetic basis of meiotic sex ratio variation. © 2014 Botanical Society of America, Inc.

  16. The financial consequences of too many men: sex ratio effects on saving, borrowing, and spending.

    Science.gov (United States)

    Griskevicius, Vladas; Tybur, Joshua M; Ackerman, Joshua M; Delton, Andrew W; Robertson, Theresa E; White, Andrew E

    2012-01-01

    The ratio of males to females in a population is an important factor in determining behavior in animals. We propose that sex ratio also has pervasive effects in humans, such as by influencing economic decisions. Using both historical data and experiments, we examined how sex ratio influences saving, borrowing, and spending in the United States. Findings show that male-biased sex ratios (an abundance of men) lead men to discount the future and desire immediate rewards. Male-biased sex ratios decreased men's desire to save for the future and increased their willingness to incur debt for immediate expenditures. Sex ratio appears to influence behavior by increasing the intensity of same-sex competition for mates. Accordingly, a scarcity of women led people to expect men to spend more money during courtship, such as by paying more for engagement rings. These findings demonstrate experimentally that sex ratio influences human decision making in ways consistent with evolutionary biological theory. Implications for sex ratio effects across cultures are discussed.

  17. Sex ratios in the Arctic--do man-made chemicals matter?

    DEFF Research Database (Denmark)

    Bjerregaard, Peter; Chatwood, Susan; Denning, Bryany

    2013-01-01

    The objective was to analyze the variation of secondary sex ratios across the Arctic and to estimate the time trend. The rationale for this was claims in news media that, in the Arctic, sex ratios have become reduced due to exposure to anthropogenic contaminants in the environment....

  18. The potential pitfalls of studying adult sex ratios at aggregate levels in humans

    NARCIS (Netherlands)

    Pollet, Thomas V.; Stoevenbelt, Andrea H.; Kuppens, Toon

    2017-01-01

    Human adult sex ratios have been studied extensively across the biological and social sciences. While several studies have examined adult sex ratio effects in a multilevel perspective, many studies have focused on effects at an aggregated level only. In this paper, we review some key issues relating

  19. Phenotypic sex ratios of Atriplex canescens shrubs in relation to cattle browsing

    Science.gov (United States)

    Andres F. Cibils; David M. Swift; Richard H. Hart

    2001-01-01

    Previous studies conducted at our research site on the shortgrass steppe in Colorado showed that phenotypic sex ratios of tetraploid fourwing saltbush (Atriplex canescens Pursh [Nutt]) shrubs were less female biased in grazed pastures than in adjacent exclosures. The potential effects of cattle browsing on shrub sex ratios were studied both in the field and in a...

  20. Territory Quality and Plumage Morph Predict Offspring Sex Ratio Variation in a Raptor.

    Directory of Open Access Journals (Sweden)

    Nayden Chakarov

    Full Text Available Parents may adapt their offspring sex ratio in response to their own phenotype and environmental conditions. The most significant causes for adaptive sex-ratio variation might express themselves as different distributions of fitness components between sexes along a given variable. Several causes for differential sex allocation in raptors with reversed sexual size dimorphism have been suggested. We search for correlates of fledgling sex in an extensive dataset on common buzzards Buteo buteo, a long-lived bird of prey. Larger female offspring could be more resource-demanding and starvation-prone and thus the costly sex. Prominent factors such as brood size and laying date did not predict nestling sex. Nonetheless, lifetime sex ratio (LSR, potentially indicative of individual sex allocation constraints and overall nestling sex were explained by territory quality with more females being produced in better territories. Additionally, parental plumage morphs and the interaction of morph and prey abundance tended to explain LSR and nestling sex, indicating local adaptation of sex allocation However, in a limited census of nestling mortality, not females but males tended to die more frequently in prey-rich years. Also, although females could have potentially longer reproductive careers, a subset of our data encompassing full individual life histories showed that longevity and lifetime reproductive success were similarly distributed between the sexes. Thus, a basis for adaptive sex allocation in this population remains elusive. Overall, in common buzzards most major determinants of reproductive success appeared to have no effect on sex ratio but sex allocation may be adapted to local conditions in morph-specific patterns.

  1. National, regional, and global sex ratios of infant, child, and under-5 mortality and identification of countries with outlying ratios: a systematic assessment

    OpenAIRE

    Alkema, Leontine; Chao, Fengqing; You, Danzhen; Pedersen, Jon; Sawyer, Cheryl C

    2014-01-01

    Background: Under natural circumstances, the sex ratio of male to female mortality up to the age of 5 years is greater than one but sex discrimination can change sex ratios. The estimation of mortality by sex and identification of countries with outlying levels is challenging because of issues with data availability and quality, and because sex ratios might vary naturally based on differences in mortality levels and associated cause of death distributions. Methods: For this systematic anal...

  2. Inter-Annual Variability of Fledgling Sex Ratio in King Penguins.

    Directory of Open Access Journals (Sweden)

    Célia Bordier

    Full Text Available As the number of breeding pairs depends on the adult sex ratio in a monogamous species with biparental care, investigating sex-ratio variability in natural populations is essential to understand population dynamics. Using 10 years of data (2000-2009 in a seasonally monogamous seabird, the king penguin (Aptenodytes patagonicus, we investigated the annual sex ratio at fledging, and the potential environmental causes for its variation. Over more than 4000 birds, the annual sex ratio at fledging was highly variable (ranging from 44.4% to 58.3% of males, and on average slightly biased towards males (51.6%. Yearly variation in sex-ratio bias was neither related to density within the colony, nor to global or local oceanographic conditions known to affect both the productivity and accessibility of penguin foraging areas. However, rising sea surface temperature coincided with an increase in fledging sex-ratio variability. Fledging sex ratio was also correlated with difference in body condition between male and female fledglings. When more males were produced in a given year, their body condition was higher (and reciprocally, suggesting that parents might adopt a sex-biased allocation strategy depending on yearly environmental conditions and/or that the effect of environmental parameters on chick condition and survival may be sex-dependent. The initial bias in sex ratio observed at the juvenile stage tended to return to 1∶1 equilibrium upon first breeding attempts, as would be expected from Fisher's classic theory of offspring sex-ratio variation.

  3. Sex Dimorphism of the Heart Diameters and Cardiothoracic Ratios ...

    African Journals Online (AJOL)

    Objective: To determine gender associated differences in the cardiothoracic ratio (CTR) and heart diameters in a normal Nigerian population. Subject and Method: The normal heart diameters and cardiothoracic ratios were measured from posteroanterior (PA) chest radiographs of healthy 510 male and 508 female ...

  4. Mother's prior intrauterine position affects the sex ratio of her offspring in house mice.

    Science.gov (United States)

    Vandenbergh, J G; Huggett, C L

    1994-11-08

    Sex ratio alterations related to environmental factors occur in several mammals, but no mechanism has been identified to explain the adjustment. Intrauterine position (IUP) may provide the context in which such alterations occur. Previous studies on house mice and gerbils reveal that the position of a fetus in the uterus in relation to the sex of its neighbors influences its later anatomy, physiology, and behavior. The anogenital distance (AGD) of females located between two males (2M) is longer than that of females not between two males (OM). We have found that the IUP, as determined by cesarean section and by an index of the AGD, correlates with the sex ratio of the litters produced by female mice. The sex ratio of the first litter born to 2M females was 58% males, for 1M females was 51% males and for OM females was 42% males. The effect on sex ratio continues into the second litter. The number of pups produced by mothers of different IUPs in her first two litters did not differ, suggesting that the sex ratio adjustment occurs prior to parturition. These results provide a basis for the natural variability observed in sex ratios of litter-bearing mammals and suggest that one or more intrauterine mechanisms may be responsible for environmentally related sex ratio alterations.

  5. The sex ratio of siblings of individuals with a history of developmental language disorder

    DEFF Research Database (Denmark)

    Mouridsen, Svend Erik; Hauschild, Karen-Marie

    2010-01-01

    There is a well documented predominance of males diagnosed with neurodevelopmental disorders. The influence of sex steroids upon brain development has been suggested to mediate sex differences in developmental psychopathology, and has been epitomized in the 'extreme male brain theory......'. The objective of this study was to extend previous studies dealing with the extreme male brain theory and to study the sex ratio (proportion of males) in the siblings of 469 individuals with a developmental language disorder (DLD) who were consecutively assessed in the same clinic during a period of 10 years....... Among their 908 live-born siblings, 503 were males and 405 females. This yields a sex ratio of 0.554, which is significantly higher than the Danish live birth sex ratio of 0.514 over the same period (P = 0.02). Our findings are consistent with the hypothesis that male sex hormones may be implicated...

  6. Using Approximate Bayesian Computation to infer sex ratios from acoustic data.

    Science.gov (United States)

    Lehnen, Lisa; Schorcht, Wigbert; Karst, Inken; Biedermann, Martin; Kerth, Gerald; Puechmaille, Sebastien J

    2018-01-01

    Population sex ratios are of high ecological relevance, but are challenging to determine in species lacking conspicuous external cues indicating their sex. Acoustic sexing is an option if vocalizations differ between sexes, but is precluded by overlapping distributions of the values of male and female vocalizations in many species. A method allowing the inference of sex ratios despite such an overlap will therefore greatly increase the information extractable from acoustic data. To meet this demand, we developed a novel approach using Approximate Bayesian Computation (ABC) to infer the sex ratio of populations from acoustic data. Additionally, parameters characterizing the male and female distribution of acoustic values (mean and standard deviation) are inferred. This information is then used to probabilistically assign a sex to a single acoustic signal. We furthermore develop a simpler means of sex ratio estimation based on the exclusion of calls from the overlap zone. Applying our methods to simulated data demonstrates that sex ratio and acoustic parameter characteristics of males and females are reliably inferred by the ABC approach. Applying both the ABC and the exclusion method to empirical datasets (echolocation calls recorded in colonies of lesser horseshoe bats, Rhinolophus hipposideros) provides similar sex ratios as molecular sexing. Our methods aim to facilitate evidence-based conservation, and to benefit scientists investigating ecological or conservation questions related to sex- or group specific behaviour across a wide range of organisms emitting acoustic signals. The developed methodology is non-invasive, low-cost and time-efficient, thus allowing the study of many sites and individuals. We provide an R-script for the easy application of the method and discuss potential future extensions and fields of applications. The script can be easily adapted to account for numerous biological systems by adjusting the type and number of groups to be

  7. Change in schistosome sex ratio under the influence of a biotic environmental-related factor.

    Science.gov (United States)

    Moné, H

    1997-04-01

    Schistosoma mansoni is a dioecious trematode responsible for intestinal schistosomiasis in man. The sex ratio was determined for S. mansoni adults derived from cercariae obtained from infected Biomphalaria glabrata maintained in the presence of the nonvector molluse. Marisa cornuarietis. The presence of M. cornuarietis is responsible for enhanced growth of B. glabrata and for a change in the sex ratio of the schistosome, which becomes more male-biased as compared to control snails maintained in aquaria lacking M. cornuarietis. This is the first time the presence of another species in the environment has been shown to influence schistosome sex ratios. Two nonexclusive hypotheses are proposed to explain this variation in the sex ratio: sexual competition between male and female sporocysts; and sex reversal.

  8. The evolution of sex roles in birds is related to adult sex ratio

    OpenAIRE

    Liker, András; Freckleton, Robert P.; Székely, Tamás

    2013-01-01

    Sex-role reversal represents a formidable challenge for evolutionary biologists, since it is not clear which ecological, life-history or social factors facilitated conventional sex roles (female care and male-male competition for mates) to be reversed (male care and female-female competition). Classic theories suggested ecological or life-history predictors of role reversal, but most studies failed to support these hypotheses. Recent theory however predicts that sex-role reversal should be dr...

  9. Sex ratios in the two Germanies: a test of the economic stress hypothesis.

    Science.gov (United States)

    Catalano, Ralph A

    2003-09-01

    Literature describing temporal variation in the secondary sex ratio among humans reports an association between population stressors and declines in the odds of male birth. Explanations of this phenomenon draw on reports that stressed females spontaneously abort male more than female fetuses, and that stressed males exhibit reduced sperm motility. This work has led to the argument that population stress induced by a declining economy reduces the human sex ratio. No direct test of this hypothesis appears in the literature. Here, a test is offered based on a comparison of the sex ratio in East and West Germany for the years 1946 to 1999. The theory suggests that the East German sex ratio should be lower in 1991, when East Germany's economy collapsed, than expected from its own history and from the sex ratio in West Germany. The hypothesis is tested using time-series modelling methods. The data support the hypothesis. The sex ratio in East Germany was at its lowest in 1991. This first direct test supports the hypothesis that economic decline reduces the human sex ratio.

  10. Paternal effects on the human sex ratio at birth: evidence from interracial crosses.

    Science.gov (United States)

    Khoury, M J; Erickson, J D; James, L M

    1984-01-01

    The effects of interracial crossing on the human sex ratio at birth were investigated using United States birth-certificate data for 1972-1979. The sex ratio was 1.059 for approximately 14 million singleton infants born to white couples, 1.033 for 2 million born to black couples, and 1.024 for 64,000 born to American Indian couples. Paternal and maternal race influences on the observed racial differences in sex ratio were analyzed using additional data on approximately 97,000 singleton infants born to white-black couples and 60,000 born to white-Indian couples. After adjustment for mother's race, white fathers had significantly more male offspring than did black fathers (ratio of sex ratios [RSR] = 1.027) and Indian fathers (RSR = 1.022). On the other hand, after adjustment for father's race, white mothers did not have more male offspring than did black mothers (RSR = 0.998) or Indian mothers (RSR = 1.009). The paternal-race effect persisted after adjustment for parental ages, education, birth order, and maternal marital status. The study shows that the observed racial differences in the sex ratio at birth are due to the effects of father's race and not the mother's. The study points to paternal determinants of the human sex ratio at fertilization and/or of the prenatal differential sex survival. PMID:6496474

  11. Sex ratios in juveniles and adults of Dichroplus maculipennis (Blanchard and Borellia bruneri (Rehn (Orthoptera: Acrididae

    Directory of Open Access Journals (Sweden)

    Yanina Mariottini

    2015-06-01

    Full Text Available Dichroplus maculipennis and Borellia bruneri are two of the 18 grasshopper species of actual or potential economic relevance as pests in Argentina. The objective of this study was to estimate the sex ratios for adults and older nymphs of D. maculipennis and B. bruneri in the field, and analyze possible temporal variations. The study was conducted during seven seasons (2005-06 to 2011-12 in representative plant communities of the southern Pampas region. A total of 4536 individuals of D. maculipennis, and 6038 individuals of B. bruneri were collected. The sex ratio registered in older nymphs for D. maculipennis and B. bruneri did not deviate from a 1:1 ratio (p > 0.05, suggesting that these species have such a primary sex ratio. However, a significant bias in sex composition in adults of both species was observed (p < 0.05. The sex ratio in adults of D. maculipennis was different in five of the 18 sampling dates carried out. In three sampling dates it was biased toward males, while in the other two it was biased toward females. Taking into account the sex ratio by sampling season, significant differences were recorded in two seasons. In 2007-08 the sex ratio was biased toward males (1 F:2.26 M, while in 2008-09 it was biased toward females (1.35 F:1 M. The sex ratio in adults of B. bruneri was always biased toward males (p < 0.05. We conclude that results obtained in this study indicate that various factors like differential survival, dispersion, predation, among others, could have modified the primary sex ratio in these species.

  12. Sex ratio in two species of Pegoscapus wasps (Hymenoptera: Agaonidae that develop in figs: can wasps do mathematics, or play sex ratio games?

    Directory of Open Access Journals (Sweden)

    William Ramírez-Benavides

    2009-09-01

    Full Text Available The fig pollinating wasps (Hymenoptera: Agaonidae have obligate arrhenotoky and a breeding structure that fits local mate competition (LMC. It has been traditionally assumed that LMC organisms adjust the sex ratio by laying a greater proportion of male eggs when there is superparasitism (several foundresses in a host. We tested the assumption with two wasp species, Pegoscapus silvestrii, pollinator of Ficus pertusa and Pegoscapus tonduzi, pollinator of Ficus eximia (= F. citrifolia, in the Central Valley of Costa Rica. Total number of wasps and seeds were recorded in individual isolated naturally colonized syconia. There was a constant additive effect between the number of foundresses and the number of males produced in the brood of a syconium, while the number of females decreased. Both wasp species seem to have precise sex ratios and probably lay the male eggs first in the sequence, independently of superparasitism and clutch size: consequently, they have a non-random sex allocation. Each syconium of Ficus pertusa and of F. eximia colonized by one foundress had similar mean numbers of females, males, and seeds. The two species of wasps studied do not seem to adjust the sex ratio when there is superparasitism. Pollinating fig wasp behavior is better explained by those models not assuming that females do mathematical calculations according to other females’ sex ratios, size, number of foundresses, genetic constitution, clutch size or environmental conditions inside the syconium. Our results are in agreement with the constant male number hypothesis, not with sex ratio games. Rev. Biol. Trop. 57 (3: 605-621. Epub 2009 September 30.

  13. The male handicap: male-biased mortality explains skewed sex ratios in brown trout embryos.

    Science.gov (United States)

    Morán, P; Labbé, L; Garcia de Leaniz, C

    2016-12-01

    Juvenile sex ratios are often assumed to be equal for many species with genetic sex determination, but this has rarely been tested in fish embryos due to their small size and absence of sex-specific markers. We artificially crossed three populations of brown trout and used a recently developed genetic marker for sexing the offspring of both pure and hybrid crosses. Sex ratios (SR = proportion of males) varied widely one month after hatching ranging from 0.15 to 0.90 (mean = 0.39 ± 0.03). Families with high survival tended to produce balanced or male-biased sex ratios, but SR was significantly female-biased when survival was low, suggesting that males sustain higher mortality during development. No difference in SR was found between pure and hybrid families, but the existence of sire × dam interactions suggests that genetic incompatibility may play a role in determining sex ratios. Our findings have implications for animal breeding and conservation because skewed sex ratios will tend to reduce effective population size and bias selection estimates. © 2016 The Authors.

  14. Sex ratios, mating frequencies and relative abundance of sympatric millipedes in the genus Chersastus (Diplopoda: Pachybolidae

    Directory of Open Access Journals (Sweden)

    Mark Ian Cooper

    2014-12-01

    Full Text Available Three hypotheses exist for explaining climbing behavior in millipedes: 1 waterlogging, 2 detritus limiting, and 3 mate avoidance. Data of sex ratios, mating frequency and relative abundance are provided to suggest an alternative explanation for the pattern in sympatric forest millipedes. Sex ratio differences - from equality - were tested using a G-test comparing millipedes on and above ground. Mating frequencies were calculated based on the percentage of paired individuals. Relative abundance may correlate with male-biases in the sex ratios. All three factors suggest Chersastus inscriptus has a higher reproductive potential than C. anulatus. This is evidence for mating hotspots.

  15. Persistent sex-by-environment effects on offspring fitness and sex-ratio adjustment in a wild bird population.

    Science.gov (United States)

    Bowers, E Keith; Thompson, Charles F; Sakaluk, Scott K

    2015-03-01

    A major component of sex-allocation theory, the Trivers-Willard model (TWM), posits that sons and daughters are differentially affected by variation in the rearing environment. In many species, the amount of parental care received is expected to have differing effects on the fitness of males and females. When this occurs, the TWM predicts that selection should favour adjustment of the offspring sex ratio in relation to the expected fitness return from offspring. However, evidence for sex-by-environment effects is mixed, and little is known about the adaptive significance of producing either sex. Here, we test whether offspring sex ratios vary according to predictions of the TWM in the house wren (Troglodytes aedon, Vieillot). We also test the assumption of a sex-by-environment effect on offspring using two experiments, one in which we manipulated age differences among nestlings within broods, and another in which we held nestling age constant but manipulated brood size. As predicted, females with high investment ability overproduced sons relative to those with lower ability. Males were also overproduced early within breeding seasons. In our experiments, the body mass of sons was more strongly affected by the sibling-competitive environment and resource availability than that of daughters: males grew heavier than females when reared in good conditions but were lighter than females when in poor conditions. Parents rearing broods with 1:1 sex ratios were more productive than parents rearing broods biased more strongly towards sons or daughters, suggesting that selection favours the production of mixed-sex broods. However, differences in the condition of offspring as neonates persisted to adulthood, and their reproductive success as adults varied with the body mass of sons, but not daughters, prior to independence from parental care. Thus, selection should favour slight but predictable variations in the sex ratio in relation to the quality of offspring that parents are

  16. Live birth sex ratios and father's geographic origins in Jerusalem, 1964-1976.

    Science.gov (United States)

    Groeger, J; Opler, M; Kleinhaus, K; Perrin, M C; Calderon-Margalit, R; Manor, O; Paltiel, O; Conley, D; Harlap, S; Malaspina, D

    2017-05-06

    To examine whether ancestry influenced sex ratios of offspring in a birth cohort before parental antenatal sex selection influenced offspring sex. We measured the sex ratio as the percent of males according to countries of birth of paternal and maternal grandfathers in 91,459 live births from 1964 to 1976 in the Jerusalem Perinatal Study. Confidence limits (CI) were computed based on an expected sex ratio of 1.05, which is 51.4% male. Of all live births recorded, 51.4% were male. Relative to Jewish ancestry (51.4% males), significantly more males (1,761) were born to Muslim ancestry (54.5, 95% CI = 52.1-56.8, P = 0.01). Among the former, sex ratios were not significantly associated with paternal or maternal age, education, or offspring's birth order. Consistent with a preference for male offspring, the sex ratio decreased despite increasing numbers of births over the 13-year period. Sex ratios were not affected by maternal or paternal origins in North Africa or Europe. However, the offspring whose paternal grandfathers were born in Western Asia included fewer males than expected (50.7, 50.1-51.3, P = 0.02), whether the father was born abroad (50.7) or in Israel (50.8). This was observed for descendents of paternal grandfathers born in Lebanon (47.6), Turkey (49.9), Yemen & Aden (50.2), Iraq (50.5), Afghanistan (50.5), Syria (50.6), and Cyprus (50.7); but not for those from India (51.5) or Iran (51.9). The West Asian group showed the strongest decline in sex ratios with increasing paternal family size. A decreased sex ratio associated with ancestry in Western Asia is consistent with reduced ability to bear sons by a subset of Jewish men in the Jerusalem cohort. Lower sex ratios may be because of pregnancy stress, which may be higher in this subgroup. Alternatively, a degrading Y chromosome haplogroup or other genetic or epigenetic differences on male germ lines could affect birth ratios, such as differential exposure to an environmental agent, dietary

  17. Live birth sex ratios and father’s geographic origins in Jerusalem, 1964–1976

    Science.gov (United States)

    Groeger, J; Opler, M; Kleinhaus, K; Perrin, MC; Calderon-Margalit, R; Manor, O; Paltiel, O; Conley, D; Harlap, S; Malaspina, D

    2016-01-01

    Objective To examine whether ancestry influenced sex ratios of offspring in a birth cohort before parental antenatal sex selection influenced offspring sex. Methods We measured the sex ratio as the percent of males according to countries of birth of paternal and maternal grandfathers in 91,459 live births from 1964 to 1976 in the Jerusalem Perinatal Study. Confidence limits (CI) were computed based on an expected sex ratio of 1.05, which is 51.4% male. Results Of all live births recorded, 51.4% were male. Relative to Jewish ancestry (51.4% males), significantly more males (1,761) were born to Muslim ancestry (54.5, 95% CI=52.1–56.8, p=.01). Among the former, sex ratios were not significantly associated with paternal or maternal age, education, or offspring’s birth order. Consistent with a preference for male offspring, the sex ratio decreased despite increasing numbers of births over the 13-year period. Sex ratios were not affected by maternal or paternal origins in North Africa or Europe. However, the offspring whose paternal grandfathers were born in Western Asia included fewer males than expected (50.7, 50.1–51.3, p=.02), whether the father was born abroad (50.7) or in Israel (50.8). This was observed for descendents of paternal grandfathers born in Lebanon (47.6), Turkey (49.9), Yemen & Aden (50.2), Iraq (50.5), Afghanistan (50.5), Syria (50.6), and Cyprus (50.7); but not for those from India (51.5) or Iran (51.9). The West Asian group showed the strongest decline in sex ratios with increasing paternal family size. Conclusions A decreased sex ratio associated with ancestry in Western Asia is consistent with reduced ability to bear sons by a subset of Jewish men in the Jerusalem cohort. Lower sex ratios may be due to pregnancy stress, which may be higher in this subgroup. Alternatively, a degrading Y chromosome haplogroup or other genetic or epigenetic differences on male germ lines could affect birth ratios, such as differential exposure to an

  18. Sex ratio at birth and mortality rates are negatively related in humans.

    Directory of Open Access Journals (Sweden)

    Madhukar Shivajirao Dama

    Full Text Available Evolutionary theory posits that resource availability and parental investment ability could signal offspring sex selection, in order to maximize reproductive returns. Non-human studies have provided evidence for this phenomenon, and maternal condition around the time of conception has been identified as most important factor that influence offspring sex selection. However, studies on humans have reported inconsistent results, mostly due to use of disparate measures as indicators of maternal condition. In the present study, the cross-cultural differences in human natal sex ratio were analyzed with respect to indirect measures of condition namely, life expectancy and mortality rate. Multiple regression modeling suggested that mortality rates have distinct predictive power independent of cross-cultural differences in fertility, wealth and latitude that were earlier shown to predict sex ratio at birth. These findings suggest that sex ratio variation in humans may relate to differences in parental and environmental conditions.

  19. Sex differences in behavioral and PKA cascade responses to repeated cocaine administration.

    Science.gov (United States)

    Zhou, Luyi; Sun, Wei-Lun; Weierstall, Karen; Minerly, Ana Christina; Weiner, Jan; Jenab, Shirzad; Quinones-Jenab, Vanya

    2016-10-01

    Previous studies have shown sex different patterns in behavioral responses to cocaine. Here, we used between-subject experiment design to study whether sex differences exist in the development of behavioral sensitization and tolerance to repeated cocaine, as well as the role of protein kinase A (PKA) signaling cascade in this process. Ambulatory and rearing responses were recorded in male and female rats after 1 to 14 days of administration of saline or cocaine (15 mg/kg; ip). Correspondent PKA-associated signaling in the nucleus accumbens (NAc) and caudate-putamen (CPu) was measured at each time point. Our results showed that females exhibited higher cocaine-induced behavioral responses and developed behavioral sensitization and tolerance faster than males. Whereas females developed behavioral sensitization to cocaine after 2 days and tolerance after 14 days, male rats developed sensitization after 5 days. In addition, cocaine induced a sexual dimorphic pattern in the progression of neuronal adaptations on the PKA cascade signaling in region (NAc vs. CPu) and time (days of cocaine administration)-dependent manners. In general, more PKA signaling cascade changes were found in the NAc of males on day 5 and in the CPu of females with repeated cocaine injection. In addition, in females, behavioral activities positively correlated with FosB levels in the NAc and CPu and negatively correlated with Cdk5 and p35 in the CPu, while no correlation was observed in males. Our studies suggest that repeated cocaine administration induced different patterns of behavioral and molecular responses in the PKA cascade in male and female rats.

  20. Does predation control adult sex ratios and longevities in marine pelagic copepods?

    DEFF Research Database (Denmark)

    Hirst, A.G.; Bonnet, D.; Conway, D.V.P.

    2010-01-01

    We assess the causes of adult sex ratio skew in marine pelagic copepods by examining changes in these ratios between the juveniles and adults, sexual differences in juvenile stage durations, and mortality rates of adults in the field and laboratory (when free from predators). In the field, late...... copepodite stages (CIV and CV) commonly have sex ratios that are either not significantly different from equity (1 : 1), or slightly male biased. By contrast, in adults, these ratios are commonly significantly biased toward female dominance. Sex ratio skews are therefore primarily attributable to processes...... in adults. Members of the non-Diaptomoidea have especially skewed adult ratios; in the members Oithonidae and Clausocalanidae this is not generated from differences between male and female adult physiological longevity (i.e., laboratory longevity when free of predators). In the genera Acartia, Oithona...

  1. SEASONAL-VARIATION IN THE SEX-RATIO OF MARSH HARRIER CIRCUS-AERUGINOSUS BROODS

    NARCIS (Netherlands)

    ZIJLSTRA, M; DAAN, S; BRUINENBERGRINSMA, J

    1992-01-01

    1. Analysis of the sexes of 2260 nestlings in 735 marsh harrier broods revealed an overall excess [sex ratio (SR) = 54.8%] of males, and a significant increase in the proportion of males with progressive laying date (d = day of the year): In [SR/(1-SR)] = -1.286 + 0.013 d. 2. We argue that it is

  2. Comparative AFLP reveals paternal sex ratio chromosome specific DNA sequences in the parasitoid wasp Trichogramma kaykai

    NARCIS (Netherlands)

    Vugt, van J.J.F.A.; Hulst, van der R.G.M.; Pruijssers, A.; Verbaarschot, P.G.H.; Stouthamer, R.; Jong, de H.

    2009-01-01

    The parasitoid wasp Trichogramma kaykai with a haplo-diploid sex determination has a B chromosome called the paternal sex ratio (PSR) chromosome that confers paternal genome loss during early embryogenesis, resulting in male offspring. So far, it is not well known whether the PSR chromosome has

  3. Steroid Hormones and Female Energy Balance: Relation to Offspring Primary Sex Ratio

    NARCIS (Netherlands)

    Aslam, M.L.; Woelders, H.

    2017-01-01

    Birds can manipulate the offspring sex ratio under natural and experimental conditions. Various factors related to the avian mother, as well as her eggs, have been reported to be linked with the sex determination process. These factors appear to affect the chance of laying a male or female egg

  4. Invited commentary: Natural versus unnatural sex ratios--a quandary of modern times.

    Science.gov (United States)

    Wilcox, Allen J; Baird, Donna D

    2011-12-15

    The typical dilemma with sex-ratio findings is that when they are real, they aren't interesting, and when they are interesting, they aren't real. In this issue of the Journal, Fernández et al. (Am J Epidemiol. 2011;174(12):1327-1331) describe a deviation of the sex ratio that is apparently both large and real. There was a temporary but distinct spike in the proportion of boys born in Cuba around the time of the collapse of the national economy during the 1990s. Although an excess of boys does not fit the prevailing biologic theory regarding maternal stress and the sex ratio, the data are consistent with results from the Dutch famine (where population-level deprivation was even more extreme). A new quandary arises in the modern era with interpretation of the sex ratio: If the decision to abort a pregnancy is influenced by the sex of the fetus, a change in the behavior of even a small proportion of women could influence the sex ratio at birth. The possible role of sex selection in the Cuban context is discussed.

  5. The sex ratio distortion in the human head louse is conserved over time

    Directory of Open Access Journals (Sweden)

    Biliński Szczepan M

    2004-05-01

    Full Text Available Abstract Background At the turn of the 19th century the first observations of a female-biased sex ratio in broods and populations of the head louse, Pediculus humanus capitis, had been reported. A study by Buxton in 1940 on the sex ratio of lice on prisoners in Ceylon is still today the subject of reanalyses. This sex ratio distortion had been detected in ten different countries. In the last sixty years no new data have been collected, especially on scalp infestations under economically and socially more developed conditions. Results Here we report a female bias of head lice in a survey of 480 school children in Argentina. This bias is independent of the intensity of the pediculosis, which makes local mate competition highly unlikely as the source of the aberrant sex ratio; however, other possible adaptive mechanisms cannot be discounted. These lice as well as lice from pupils in Britain were carrying several strains of the endosymbiotic bacterium Wolbachia pipientis, one of the most wide spread intracellular sex ratio distorters. Similar Wolbachia strains are also present in the pig louse, Haematopinus suis, suggesting that this endosymbiont might have a marked influence on the biology of the whole order. The presence of a related obligate nutritional bacterium in lice prevents the investigation of a causal link between sex ratio and endosymbionts. Conclusions Regardless of its origin, this sex ratio distortion in head lice that has been reported world wide, is stable over time and is a remarkable deviation from the stability of frequency-dependent selection of Fisher's sex ratio. A female bias first reported in 1898 is still present over a hundred years and a thousand generations later.

  6. Sex ratio and time to pregnancy: analysis of four large European population surveys

    DEFF Research Database (Denmark)

    Joffe, Mike; Bennett, James; Best, Nicky

    2007-01-01

    To test whether the secondary sex ratio (proportion of male births) is associated with time to pregnancy, a marker of fertility. Design Analysis of four large population surveys. Setting Denmark and the United Kingdom. Participants 49 506 pregnancies.......To test whether the secondary sex ratio (proportion of male births) is associated with time to pregnancy, a marker of fertility. Design Analysis of four large population surveys. Setting Denmark and the United Kingdom. Participants 49 506 pregnancies....

  7. Pengaruh Sex Ratio Ayam Arab Terhadap Fertilitas, Daya Tetas, Dan Bobot Tetas

    OpenAIRE

    Widi Astomo; Dian Septinova; Tintin Kurtini

    2016-01-01

    This study aimed to determine (1) This effect of sex ratio arabic chicken on fertility, hatchibility , and doc weight and (2) to determine the best sex ratio of effect arabic chicken on fertility, hatchability, and doc weight. This study was conducted in August 2015 at Tegalrejo village, Gadingrejo districk, Pringsewu regency.The research use 144 arabic chicken consisted of 18 males and 126 females. This research use the complete randomized design with 3 treatments and 6 times replications...

  8. A Multinomial Model of Fertility Choice and Offspring Sex-Ratios in India

    OpenAIRE

    Rubiana Chamarbagwala; Martin Ranger

    2007-01-01

    Fertility decline in developing countries may have unexpected demographic consequences. Although lower fertility improves nutrition, health, and human capital investments for surviving children, little is known about the relationship between fertility outcomes and female-male offspring sex-ratios. Particularly in countries with a cultural preference for sons, like India and China, fertility decline may deteriorate the already imbalanced sex-ratios. We use the fertility histories of over 90,00...

  9. The impact of sex ratio and economic status on local birth rates.

    Science.gov (United States)

    Chipman, A; Morrison, E

    2013-04-23

    Human mating and reproductive behaviour can vary depending on various mechanisms, including the local sex ratio. Previous research shows that as sex ratios become female-biased, women from economically deprived areas are less likely to delay reproductive opportunities to wait for a high-investing mate but instead begin their reproductive careers sooner. Here, we show that the local sex ratio also has an impact on female fertility schedules. At young ages, a female-biased ratio is associated with higher birth rates in the poorest areas, whereas the opposite is true for the richest areas. At older ages, a female-biased ratio is associated with higher birth rates in the richest, but not the poorest areas. These patterns suggest that female-female competition encourages poorer women to adopt a fast life-history strategy and give birth early, and richer women to adopt a slow life-history strategy and delay reproduction.

  10. Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats.

    Science.gov (United States)

    Armour, John A L; Palla, Raquel; Zeeuwen, Patrick L J M; den Heijer, Martin; Schalkwijk, Joost; Hollox, Edward J

    2007-01-01

    Recent work has demonstrated an unexpected prevalence of copy number variation in the human genome, and has highlighted the part this variation may play in predisposition to common phenotypes. Some important genes vary in number over a high range (e.g. DEFB4, which commonly varies between two and seven copies), and have posed formidable technical challenges for accurate copy number typing, so that there are no simple, cheap, high-throughput approaches suitable for large-scale screening. We have developed a simple comparative PCR method based on dispersed repeat sequences, using a single pair of precisely designed primers to amplify products simultaneously from both test and reference loci, which are subsequently distinguished and quantified via internal sequence differences. We have validated the method for the measurement of copy number at DEFB4 by comparison of results from >800 DNA samples with copy number measurements by MAPH/REDVR, MLPA and array-CGH. The new Paralogue Ratio Test (PRT) method can require as little as 10 ng genomic DNA, appears to be comparable in accuracy to the other methods, and for the first time provides a rapid, simple and inexpensive method for copy number analysis, suitable for application to typing thousands of samples in large case-control association studies.

  11. Offspring sex ratio is related to paternal train elaboration and yolk corticosterone in peafowl.

    Science.gov (United States)

    Pike, Thomas W; Petrie, Marion

    2005-06-22

    Several recent experimental studies have provided strong evidence for the ability of birds to manipulate the sex ratio of their offspring prior to laying. Using a captive population of peafowl (Pavo cristatus), we tested experimentally the effects of paternal attractiveness on offspring sex ratio, and related sex ratio deviations to egg-yolk concentrations of testosterone, 17beta-estradiol and corticosterone. When females were mated to males whose attractiveness had been experimentally reduced by removing prominent eyespot feathers from their trains, they produced significantly more female offspring, had significantly higher yolk corticosterone concentrations and tended to have lower levels of yolk testosterone than when mated to the same males with their full complement of feathers. Concentrations of 17beta-estradiol did not vary consistently with sex ratio biases. These findings add to the small number of studies providing experimental evidence that female birds can control the primary sex ratio of their offspring in response to paternal attractiveness, and highlight the possibility that corticosterone and perhaps testosterone are involved in the sex manipulation process in birds.

  12. Variation in offspring sex ratio of a long-lived sexually dimorphic raptor, the eastern imperial eagle (Aquila heliaca)

    Science.gov (United States)

    Todd E. Katzner; Daniel S. Jackson; Jamie Ivy; Evgeny A. Bragin; Andrew Dewoody

    2014-01-01

    Sex ratio theory attempts to explain observed variation in offspring sex ratio at both the population and the brood levels. In the context of low-fecundity organisms producing high-investment offspring, the drivers of adaptive variation in sex ratio are incompletely understood. For raptors that display reverse sexual dimorphism (RSD), preferential allocation of...

  13. Sibling Sex Ratio and Birth Order in Early-Onset Gender Dysphoric Adolescents

    NARCIS (Netherlands)

    Schagen, S.E.E.; Delemarre-van de Waal, H.A.; Blanchard, R.; Cohen-Kettenis, P.T.

    2012-01-01

    Several sibship-related variables have been studied extensively in sexual orientation research, especially in men. Sibling sex ratio refers to the ratio of brothers to sisters in the aggregate sibships of a group of probands. Birth order refers to the probands' position (e.g., first-born,

  14. Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury

    DEFF Research Database (Denmark)

    Timmermann, Clara Amalie Gade; Choi, Anna L; Petersen, Maria Skaalum

    2017-01-01

    This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective......% CI = 2-17%), respectively, of giving birth to a boy. In conclusion, maternal exposure to ΣPCB, DDE and methylmercury was associated with a slightly increased secondary sex ratio. The impact of paternal exposures could not be taken into account and deserves attention....

  15. Skewed Marriage Markets and Sex Ratios of Finnish People in their Twenties

    Directory of Open Access Journals (Sweden)

    Lassi Lainiala

    2014-03-01

    Full Text Available This article studies variation in regional sex ratios in Finland and outlines potential implications of the skewed sex ratios for family formation patterns. Difficulties in finding a suitable partner are typically mentioned as one of the most important reasons for remaining childless, and we explore if this reason is apparent structurally at the regional macro level. We found significant variation in sex ratios in age-groups 18–30 at the regional and sub-regional levels. Of the whole 20–29-year old population in Finland, almost 50 percent live in sub-region areas with a male surplus. As expected, a higher proportion of men compared to women appears to increase fertility of women in younger age groups. Contrary to expectations, high male-female ratios were not related to higher proportion of women living with a partner

  16. Determination of sex-ratio by birth order in an urban community in Manipur.

    Science.gov (United States)

    Brogen, Akoijam S; Shantibala, K; Rajkumari, Bishwalata; Laishram, Jalina

    2009-01-01

    To determine the sex ratio by birth order and to assess the sex preference of the couples in an urban community. A cross sectional study, in an urban community in Manipur, was conducted among the currently married couples. Data on background characteristics of the couple, family pedigree chart (of the offspring) including history of abortion, stillbirth, death of child of the couple, sex preference and Pre-natal Diagnostic Techniques (Regulation and Prevention of Misuse) Act [PNDT Act] were collected through a structured interview. Data were analyzed using descriptive and chi-square statistics. There were a total of 1777 births to the 855 couples interviewed. There were 900 females per 1000 males for the 1st birth order but the sex ratio was favorable towards females in the 2nd, 3rd and 4th birth orders. Among both the husbands and wives, being more educated was significantly associated (p<0.05) with preferring lesser number of children, using new technology for sex selection and having heard of the PNDT Act. Majority of those who wanted to use new technology for sex selection (128, 56.6%) preferred to have male child. Sex ratio in this community was favorable towards females, though it was less among the first born babies.

  17. Maintaining access to safe abortion and reducing sex ratio imbalances in Asia.

    Science.gov (United States)

    Ganatra, Bela

    2008-05-01

    High sex ratios at birth (108 boys to 100 girls or higher) are seen in China, Taiwan, South Korea and parts of India and Viet Nam. The imbalance is the result of son preference, accentuated by declining fertility. Prenatal sex detection with ultrasound followed by second trimester abortion is one of the ways sex selection manifests itself, but it is not the causative factor. Advocates and governments seeking to reverse this imbalance have largely prohibited sex detection tests and/or sex selective abortion, assuming these measures would reverse the trend. Such policies have been difficult to enforce and have met with only limited success. At the same time, such policies are starting to have adverse effects on the already limited access to safe and legal second trimester abortion for reasons other than sex selection. Moreover, the sex selection issue is being used as a platform for anti-abortion rhetoric by certain groups. Maintaining access to safe abortion and achieving a decline in high sex ratios are both important goals. Both are possible if the focus shifts to addressing the conditions that drive son preference.

  18. Different male versus female breeding periodicity helps mitigate offspring sex ratio skews in sea turtles

    Directory of Open Access Journals (Sweden)

    Graeme Clive Hays

    2014-09-01

    Full Text Available The implications of climate change for global biodiversity may be profound with those species with little capacity for adaptation being thought to be particularly vulnerable to warming. A classic case of groups for concern are those animals exhibiting temperature-dependent sex-determination (TSD, such as sea turtles, where climate warming may produce single sex populations and hence extinction. We show that, globally, female biased hatchling sex ratios dominate sea turtle populations (exceeding 3:1 in >50% records, which, at-a-glance, reiterates concerns for extinction. However, we also demonstrate that more frequent breeding by males, empirically shown by satellite tracking 23 individuals and supported by a generalized bio-energetic life history model, generates more balanced operational sex ratios (OSRs. Hence, concerns of increasingly skewed hatchling sex ratios and reduced population viability are less acute than previously thought for sea turtles. In fact, in some scenarios skewed hatchling sex ratios in groups with TSD may be adaptive to ensure optimum OSRs.

  19. Influence of electromagnetic pulse on the offspring sex ratio of male BALB/c mice.

    Science.gov (United States)

    Li, Jin-Hui; Jiang, Da-Peng; Wang, Ya-Feng; Yan, Jia-Jia; Guo, Qi-Yan; Miao, Xia; Lang, Hai-Yang; Xu, Sheng-Long; Liu, Jun-Ye; Guo, Guo-Zhen

    2017-09-01

    Public concern is growing about the exposure to electromagnetic fields (EMF) and its effect on male reproductive health. Detrimental effect of EMF exposure on sex hormones, reproductive performance and sex-ratio was reported. The present study was designed to clarify whether paternal exposure to electromagnetic pulse (EMP) affects offspring sex ratio in mice. 50 male BALB/c mice aged 5-6 weeks were exposed to EMP daily for 2 weeks before mated with non-exposed females at 0d, 7d, 14d, 21d and 28d after exposure. Sex hormones including total testosterone, LH, FSH, and GnRH were detected using radioimmunoassay. The sex ratio was examined by PCR and agarose gel electrophoresis. The results of D0, D21 and D28 showed significant increases compared with sham-exposed groups. The serum testosterone increased significantly in D0, D14, D21, and D28 compared with sham-exposed groups (p<0.05). Overall, this study suggested that EMP exposure may lead to the disturbance of reproductive hormone levels and affect the offspring sex ratio. Copyright © 2017. Published by Elsevier B.V.

  20. Different sex ratios of children born to Indian and Pakistani immigrants in Norway

    Directory of Open Access Journals (Sweden)

    Brekke Torkel

    2010-08-01

    Full Text Available Abstract Background A low female-to-male ratio has been observed in different Asian countries, but this phenomenon has not been well studied among immigrants living in Western societies. In this study, we investigated whether a low female-to-male ratio exists among Indian and Pakistani immigrants living in Norway. In particular, we investigated whether the determination of sex via ultrasound examination, a common obstetric procedure that has been used in Norway since the early 1980 s, has influenced the female-to-male ratio among children born to parents of Indian or Pakistani origin. Methods We performed a retrospective cohort study of live births in mothers of Indian (n = 1597 and Pakistani (n = 5617 origin. Data were obtained from "Statistics Norway" and the female-to-male (F/M sex ratio was evaluated among 21,325 children born, in increasing birth order, during three stratified periods (i.e., 1969-1986, 1987-1996, and 1997-2005. Results A significant low female-to-male sex ratio was observed among children in the third and fourth birth order (sex ratio 65; 95% CI 51-80 from mothers of Indian origin who gave birth after 1987. Sex ratios did not deviate from the expected natural variation in the Indian cohort from 1969 to 1986, and remained stable in the Pakistani cohort during the entire study period. However, the female-to-male sex ratio seemed less skewed in recent years (i.e., 1997-2005. Conclusion Significant differences were observed in the sex ratio of children born to mothers of Indian origin compared with children born to mothers of Pakistani origin. A skewed number of female births among higher birth orders (i.e., third or later may partly reflect an increase in sex-selective abortion among mothers of Indian origin, although the numbers are too small to draw firm conclusions. Further research is needed to explain the observed differences in the female-to-male ratio among members of these ethnic groups who reside in Norway.

  1. Elevated mortality among birds in Chernobyl as judged from skewed age and sex ratios.

    Directory of Open Access Journals (Sweden)

    Anders Pape Møller

    Full Text Available Radiation has negative effects on survival of animals including humans, although the generality of this claim is poorly documented under low-dose field conditions. Because females may suffer disproportionately from the effects of radiation on survival due to differences in sex roles during reproduction, radiation-induced mortality may result in male-skewed adult sex ratios.We estimated the effects of low-dose radiation on adult survival rates in birds by determining age ratios of adults captured in mist nets during the breeding season in relation to background radiation levels around Chernobyl and in nearby uncontaminated control areas. Age ratios were skewed towards yearlings, especially in the most contaminated areas, implying that adult survival rates were reduced in contaminated areas, and that populations in such areas could only be maintained through immigration from nearby uncontaminated areas. Differential mortality in females resulted in a strongly male-skewed sex ratio in the most contaminated areas. In addition, males sang disproportionately commonly in the most contaminated areas where the sex ratio was male skewed presumably because males had difficulty finding and acquiring mates when females were rare. The results were not caused by permanent emigration by females from the most contaminated areas because none of the recaptured birds had changed breeding site, and the proportion of individuals with morphological abnormalities did not differ significantly between the sexes for areas with normal and higher levels of contamination.These findings are consistent with the hypothesis that the adult survival rate of female birds is particularly susceptible to the effects of low-dose radiation, resulting in male skewed sex ratios at high levels of radiation. Such skewed age ratios towards yearlings in contaminated areas are consistent with the hypothesis that an area exceeding 30,000 km(2 in Chernobyl's surroundings constitutes an

  2. Increased sex ratio in Russia and Cuba after Chernobyl: a radiological hypothesis

    Science.gov (United States)

    2013-01-01

    Background The ratio of male to female offspring at birth may be a simple and non-invasive way to monitor the reproductive health of a population. Except in societies where selective abortion skews the sex ratio, approximately 105 boys are born for every 100 girls. Generally, the human sex ratio at birth is remarkably constant in large populations. After the Chernobyl nuclear power plant accident in April 1986, a long lasting significant elevation in the sex ratio has been found in Russia, i.e. more boys or fewer girls compared to expectation were born. Recently, also for Cuba an escalated sex ratio from 1987 onward has been documented and discussed in the scientific literature. Presentation of the hypothesis By the end of the eighties of the last century in Cuba as much as about 60% of the food imports were provided by the former Soviet Union. Due to its difficult economic situation, Cuba had neither the necessary insight nor the political strength to circumvent the detrimental genetic effects of imported radioactively contaminated foodstuffs after Chernobyl. We propose that the long term stable sex ratio increase in Cuba is essentially due to ionizing radiation. Testing of the hypothesis A synoptic trend analysis of Russian and Cuban annual sex ratios discloses upward jumps in 1987. The estimated jump height from 1986 to 1987 in Russia measures 0.51% with a 95% confidence interval (0.28, 0.75), p value < 0.0001. In Cuba the estimated jump height measures 2.99% (2.39, 3.60), p value < 0.0001. The hypothesis may be tested by reconstruction of imports from the world markets to Cuba and by radiological analyses of remains in Cuba for Cs-137 and Sr-90. Implications of the hypothesis If the evidence for the hypothesis is strengthened, there is potential to learn about genetic radiation risks and to prevent similar effects in present and future exposure situations. PMID:23947741

  3. Increased sex ratio in Russia and Cuba after Chernobyl: a radiological hypothesis.

    Science.gov (United States)

    Scherb, Hagen; Kusmierz, Ralf; Voigt, Kristina

    2013-08-15

    The ratio of male to female offspring at birth may be a simple and non-invasive way to monitor the reproductive health of a population. Except in societies where selective abortion skews the sex ratio, approximately 105 boys are born for every 100 girls. Generally, the human sex ratio at birth is remarkably constant in large populations. After the Chernobyl nuclear power plant accident in April 1986, a long lasting significant elevation in the sex ratio has been found in Russia, i.e. more boys or fewer girls compared to expectation were born. Recently, also for Cuba an escalated sex ratio from 1987 onward has been documented and discussed in the scientific literature. By the end of the eighties of the last century in Cuba as much as about 60% of the food imports were provided by the former Soviet Union. Due to its difficult economic situation, Cuba had neither the necessary insight nor the political strength to circumvent the detrimental genetic effects of imported radioactively contaminated foodstuffs after Chernobyl. We propose that the long term stable sex ratio increase in Cuba is essentially due to ionizing radiation. A synoptic trend analysis of Russian and Cuban annual sex ratios discloses upward jumps in 1987. The estimated jump height from 1986 to 1987 in Russia measures 0.51% with a 95% confidence interval (0.28, 0.75), p value Cuba the estimated jump height measures 2.99% (2.39, 3.60), p value Cuba and by radiological analyses of remains in Cuba for Cs-137 and Sr-90. If the evidence for the hypothesis is strengthened, there is potential to learn about genetic radiation risks and to prevent similar effects in present and future exposure situations.

  4. Differential timing and latitudinal variation in sex ratio of Aquatic Warblers during the autumn migration

    Science.gov (United States)

    Wojczulanis-Jakubas, Katarzyna; Chrostek, Małgorzata E.; Jiguet, Frédéric; Martínez, Carlos Zumalacárregui; Miguélez, David; Neto, Júlio M.

    2017-12-01

    Differential migration has been extensively reported in spring, but less so in autumn, particularly in relation to sex in monomorphic bird species. Here, we analysed the autumn passage of a monomorphic, globally threatened passerine, the Aquatic Warbler Acrocephalus paludicola throughout Western Europe, with regard to age and sex. We showed that, overall, adults migrated earlier than first-year birds, and males migrated earlier than females during the autumn migration. This may be caused by an overall social dominance of adults over immatures, and differentiated migration strategy of males and females. In addition, we found male-skewed sex proportions, with a tendency to an equalised ratio in more southern stopover sites. This may indicate a male bias in the global population or different migration strategies of the sexes. Differential migration may cause the age and sex classes to be exposed differently to various threats affecting demographic structure of the species.

  5. The Facial Width-to-Height Ratio Predicts Sex Drive, Sociosexuality, and Intended Infidelity.

    Science.gov (United States)

    Arnocky, Steven; Carré, Justin M; Bird, Brian M; Moreau, Benjamin J P; Vaillancourt, Tracy; Ortiz, Triana; Marley, Nicole

    2017-09-19

    Previous research has linked the facial width-to-height ratio (FWHR) to a host of psychological and behavioral characteristics, primarily in men. In two studies, we examined novel links between FWHR and sex drive. In Study 1, a sample of 145 undergraduate students revealed that FWHR positively predicted sex drive. There were no significant FWHR × sex interactions, suggesting that FWHR is linked to sexuality among both men and women. Study 2 replicated and extended these findings in a sample of 314 students collected from a different Canadian city, which again demonstrated links between the FWHR and sex drive (also in both men and women), as well as sociosexuality and intended infidelity (men only). Internal meta-analytic results confirm the link between FWHR and sex drive among both men and women. These results suggest that FWHR may be an important morphological index of human sexuality.

  6. Mother's prior intrauterine position affects the sex ratio of her offspring in house mice.

    OpenAIRE

    Vandenbergh, J G; Huggett, C L

    1994-01-01

    Sex ratio alterations related to environmental factors occur in several mammals, but no mechanism has been identified to explain the adjustment. Intrauterine position (IUP) may provide the context in which such alterations occur. Previous studies on house mice and gerbils reveal that the position of a fetus in the uterus in relation to the sex of its neighbors influences its later anatomy, physiology, and behavior. The anogenital distance (AGD) of females located between two males (2M) is lon...

  7. Digit Ratio (2D:4D): A Biomarker for Prenatal Sex Steroids and Adult Sex Steroids in Challenge Situations.

    Science.gov (United States)

    Manning, John; Kilduff, Liam; Cook, Christian; Crewther, Blair; Fink, Bernhard

    2014-01-01

    Digit ratio (2D:4D) denotes the relative length of the second and fourth digits. This ratio is considered to be a biomarker of the balance between fetal testosterone (T) and estrogen (E) in a narrow window of early ontogeny. Evidence for this assertion is derived from direct and indirect measures of prenatal hormonal exposure (in experimental animals, via amniotic fluid samples and in the study of sex-typical traits) in relation to 2D:4D. In contrast, the relationships between 2D:4D and levels of sex steroids in adults are less clear, as many correlational studies of 2D:4D and adult sex steroids have concluded that this association is statistically non-significant. Here, we suggest that in order to understand the link between 2D:4D and sex hormones, one must consider both fetal organizing and adult activating effects of T and E. In particular, we hypothesize that 2D:4D correlates with organizing effects on the endocrine system that moderate activating effects in adulthood. We argue that this is particularly evident in "challenging" conditions such as aggressive and sexual encounters, in which individuals show increased levels of T. We discuss this refinement of the 2D:4D paradigm in relation to the links between 2D:4D and sports performance, and aggression.

  8. Adult sex ratios and their implications for cooperative breeding in birds.

    Science.gov (United States)

    Komdeur, Jan; Székely, Tamás; Long, Xiaoyan; Kingma, Sjouke A

    2017-09-19

    Cooperative breeding is a form of breeding system where in addition to a core breeding pair, one or more usually non-breeding individuals provide offspring care. Cooperative breeding is widespread in birds, but its origin and maintenance in contemporary populations are debated. Although deviations in adult sex ratio (ASR, the proportion of males in the adult population) have been hypothesized to influence the occurrence of cooperative breeding because of the resulting surplus of one sex and limited availability of breeding partners, this hypothesis has not been tested across a wide range of taxa. By using data from 188 bird species and phylogenetically controlled analyses, we show that cooperatively breeding species have more male-biased ASRs than non-cooperative species. Importantly, ASR predicts helper sex ratio: in species with more male-biased ASR, helper sex ratio is also more male biased. We also show that offspring sex ratios do not predict ASRs, so that the skewed ASRs emerge during the period when individuals aim to obtain a breeding position or later during adulthood. In line with this result, we found that ASR (among both cooperatively and non-cooperatively breeding species) is inversely related to sex bias in dispersal distance, suggesting that the cost of dispersal is more severe for the further-dispersing sex. As females usually disperse further in birds, this explains the generally male-biased ASR, and in combination with benefits of philopatry for males, this probably explains why ASR is more biased in cooperatively breeding species. Taken together, our results suggest that a sex bias in helping in cooperatively breeding species relates to biased ASRs. We propose that this relationship is driven by sex-specific costs and benefits of dispersal and helping, as well as other demographic factors. Future phylogenetic comparative and experimental work is needed to establish how this relationship emerges.This article is part of the themed issue 'Adult sex

  9. The Relationship of Body Length and Ratio Pappilla with Sex in Gobi Fish (Sicyopterus macrostetholepis

    Directory of Open Access Journals (Sweden)

    Rona Taula Sari

    2017-07-01

    Full Text Available Research about the relationship of body length and ratio papilla with sex in goby fish (S. macrostetholepis Blkr. has been done at Animal Structure and Developmental Laboratory, Biologi Department, Faculty of Matematics and Natural Sciences, Andalas University, Padang, which purposed to analyse the relationship of body length and ratio papilla with sex of goby fish (S. macrostetholepis Blkr.. The samples were taken in wild stream area at Batangkuranji river, Padang City. This research used descriptive method and data were analyzed by qualitatively and quantitatively. The results of investigation showed that in several goby fishes (S. macrostetholepis Blkr. with different sex had the same of body length and the same of ratio papilla. So, there was not relationship between of body length and ratio papilla with sex.  Goby fishes (S. macrostetholepis Blkr. it belongs to the hermaphrodite protogini, which the androgynous young females, while in adulthood, it would change sex to male. The results of this study are expected to add to the treasures of knowledge and information about reproductive gobies (S. macrostetholepis Blkr. in the preservation and development of fish farming.   

  10. Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization

    Science.gov (United States)

    Tan, Kun; An, Lei; Miao, Kai; Ren, Likun; Hou, Zhuocheng; Tao, Li; Zhang, Zhenni; Wang, Xiaodong; Xia, Wei; Liu, Jinghao; Wang, Zhuqing; Xi, Guangyin; Gao, Shuai; Sui, Linlin; Zhu, De-Sheng; Wang, Shumin; Wu, Zhonghong; Bach, Ingolf; Chen, Dong-bao; Tian, Jianhui

    2016-01-01

    Dynamic epigenetic reprogramming occurs during normal embryonic development at the preimplantation stage. Erroneous epigenetic modifications due to environmental perturbations such as manipulation and culture of embryos during in vitro fertilization (IVF) are linked to various short- or long-term consequences. Among these, the skewed sex ratio, an indicator of reproductive hazards, was reported in bovine and porcine embryos and even human IVF newborns. However, since the first case of sex skewing reported in 1991, the underlying mechanisms remain unclear. We reported herein that sex ratio is skewed in mouse IVF offspring, and this was a result of female-biased peri-implantation developmental defects that were originated from impaired imprinted X chromosome inactivation (iXCI) through reduced ring finger protein 12 (Rnf12)/X-inactive specific transcript (Xist) expression. Compensation of impaired iXCI by overexpression of Rnf12 to up-regulate Xist significantly rescued female-biased developmental defects and corrected sex ratio in IVF offspring. Moreover, supplementation of an epigenetic modulator retinoic acid in embryo culture medium up-regulated Rnf12/Xist expression, improved iXCI, and successfully redeemed the skewed sex ratio to nearly 50% in mouse IVF offspring. Thus, our data show that iXCI is one of the major epigenetic barriers for the developmental competence of female embryos during preimplantation stage, and targeting erroneous epigenetic modifications may provide a potential approach for preventing IVF-associated complications. PMID:26951653

  11. Flock sizes and sex ratios of canvasbacks in Chesapeake Bay and North Carolina

    Science.gov (United States)

    Haramis, G.M.; Derleth, E.L.; Link, W.A.

    1994-01-01

    Knowledge of the distribution, size, and sex ratios of flocks of wintering canvasbacks (Aythya valisineria) is fundamental to understanding the species' winter ecology and providing guidelines for management. Consequently, in winter 1986-87, we conducted 4 monthly aerial photographic surveys to investigate temporal changes in distribution, size, and sex ratios of canvasback flocks in traditional wintering areas of Chesapeake Bay and coastal North Carolina. Surveys yielded 35mm imagery of 194,664 canvasbacks in 842 flocks. Models revealed monthly patterns of flock size in North Carolina and Virginia, but no pattern of change in Maryland. A stepwise analysis of flock size and sex ratio fit a common positive slope (increasing proportion male) for all state-month datasets, except for North Carolina in February where the slope was larger (P lt 0.001). State and month effects on intercepts were significant (P lt 0.001) and confirmed a previously identified latitudinal gradient in sex ratio in the survey region. There was no relationship between flock purity (% canvasbacks vs. other species) and flock size except in North Carolina in January, February, and March when flock purity was related to flock size. Contrasting characteristics in North Carolina with regard to flock size (larger flocks) and flock purity suggested that proximate factors were reinforcing flocking behavior and possibly species fidelity there. Of possible factors, the need to locate foraging sites within this large, open-water environment was hypothesized to be of primary importance. Comparison of January 1981 and 1987 sex ratios indicated no change in Maryland, but lower (P lt 0.05) canvasback sex ratios (proportion male) in Virginia and North Carolina.

  12. Effect of Temperature on Reproduction and Sex Ratio of Guppy (Poecilia reticulata Peters)

    OpenAIRE

    H. Arfah; S. Mariam; . Alimuddin

    2007-01-01

    Water temperature could affect the reproduction of broodstock and sex ratio of progeny.  In this study, broodstock of guppy (Poecilia reticulata Peters) was reared in different temperature to determine its effect on reproduction of broodstock and sex ratio of their progeny. The result of study show that broodstock reared at 27°C produced more fry (16 males mean) than that of 30°C (10 males), while broodstock reared at 33°C produced no progeny.  Percentage of male fish produced by broodstock r...

  13. Contributions of sex, testosterone, and androgen receptor CAG repeat number to virtual Morris water maze performance.

    Science.gov (United States)

    Nowak, Nicole T; Diamond, Michael P; Land, Susan J; Moffat, Scott D

    2014-03-01

    The possibility that androgens contribute to the male advantage typically found on measures of spatial cognition has been investigated using a variety of approaches. To date, evidence to support the notion that androgens affect spatial cognition in healthy young adults is somewhat equivocal. The present study sought to clarify the association between testosterone (T) and spatial performance by extending measurements of androgenicity to include both measures of circulating T as well as an androgen receptor-specific genetic marker. The aims of this study were to assess the contributions of sex, T, and androgen receptor CAG repeat number (CAGr) on virtual Morris water task (vMWT) performance in a group of healthy young men and women. The hypothesis that men would outperform women on vMWT outcomes was supported. Results indicate that CAGr may interact with T to impact navigation performance and suggest that consideration of androgen receptor sensitivity is an important consideration in evaluating hormone-behavior relationships. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Determination of Sperm Sex Ratio in Bovine Semen Using Multiplex Real-time Polymerase Chain Reaction

    Directory of Open Access Journals (Sweden)

    Trisadee Khamlor

    2014-10-01

    Full Text Available Gender selection is important in livestock industries; for example, female calves are required in the dairy industry. Sex-sorted semen is commonly used for the production of calves of the desired gender. However, assessment of the sex ratio of the sorted semen is tedious and expensive. In this study, a rapid, cost effective and reliable method for determining the sex ratio was developed using a multiplex real-time polymerase chain reaction (PCR assay. In this assay, the X and Y chromosome-specific markers, i.e., bovine proteolipid protein (PLP gene and sex-determining region Y (SRY were simultaneously quantified in a single tube. The multiplex real-time PCR assay was shown to have high amplification efficiencies (97% to 99% comparable to the separated-tube simplex real-time PCR assay. The results obtained from both assays were not significantly different (p>0.05. The multiplex assay was validated using reference DNA of known X ratio (10%, 50%, and 90% as templates. The measured %X in semen samples were the same within 95% confidence intervals as the expected values, i.e., >90% in X-sorted semen, <10% in Y-sorted semen and close to 50% in the unsorted semen. The multiplex real-time PCR assay as shown in this study can thus be used to assess purity of sex-sorted semen.

  15. The mystery of missing female children in the Caucasus: an analysis of sex ratios by birth order.

    Science.gov (United States)

    Michael, Marc; King, Lawrence; Guo, Liang; McKee, Martin; Richardson, Erica; Stuckler, David

    2013-06-01

    Official data on sex ratios at birth suggest a rise in sex-selective abortions in some post-Soviet states following the introduction of ultrasonography. However, questions remain about the validity of official data in these nations as well as whether the high sex ratios at birth are a statistical artifact. Trends in sex ratios at birth from 1985 to 2009 for 12 post-Soviet states were examined using vital registration data. For the three countries that had had a Demographic and Health Survey (DHS) in 2005-2010 (Armenia, Azerbaijan and Moldova), survey data were used to calculate sex ratios at birth according to birth order, and vital registration data for 2010 were used to estimate the number of "missing" female births (if any). Official data revealed elevated sex ratios at birth in Armenia (117), Azerbaijan (116) and Georgia (121), but not in other post-Soviet states. According to DHS data, sex ratios were high in Armenia and Azerbaijan for first births (138 and 113, respectively); if the first child was a girl, the sex ratio in Armenia was even higher for the second birth (154). Overall, the number of girls born in these countries in 2010 was 10% lower than expected, consistent with 1,972 sex-selective abortions in Armenia and 8,381 in Azerbaijan. Sex ratios did not vary by birth order in Moldova. Sex-selective abortion appears to be common in Azerbaijan and Armenia. Family planning and legal interventions are needed to address this issue.

  16. Temporal patterns in capture rate and sex ratio of forest bats in Arkansas

    Science.gov (United States)

    Roger W. Perry; S. Andrew Carter; Ronald E. Thill

    2010-01-01

    We quantified changes in capture rates and sex ratios from May to Sept. for eight species of bats, derived from 8 y of extensive mist netting in forests of the Ouachita Mountains, Arkansas. Our primary goal was to determine patterns of relative abundance for each species of bat captured over forest streams and to determine if these patterns were similar to patterns of...

  17. [Paternal exposure to occupational electromagnetic radiation and sex ratio of the offspring: a meta-analysis].

    Science.gov (United States)

    Tong, Shu-Hui; Liu, Yi-Ting; Liu, Yang

    2013-02-01

    To investigate the association between paternal exposure to occupational electromagnetic radiation and the sex ratio of the offspring. We searched various databases, including PubMed, Embase, Cochrane Library, OVID, Bioscience Information Service (BIOSIS), China National Knowledge Infrastructure, VIP Database for Chinese Technical Periodicals and Wanfang Database, for the literature relevant to the association of paternal exposure to occupational electromagnetic radiation with the sex ratio of the offspring. We conducted a meta-analysis on their correlation using Stata 11.0. There was no statistically significant difference in the sex ratio between the offspring with paternal exposure to occupational electromagnetic radiation and those without (pooled OR = 1.00 [95% CI: 0.95 -1.05], P = 0.875). Subgroup analysis of both case-control and cohort studies revealed no significant difference (pooled OR = 1.03 [95% CI: 0.99 -1.08], P = 0.104 and pooled OR = 0.98 [95% CI: 0.99 -1.08], P = 0.186, respectively). Paternal exposure to occupational electromagnetic radiation is not correlated with the sex ratio of the offspring.

  18. Sex ratio of five species of pelagic copepods from Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Saraswathy, M.; Santhakumari, V.

    Sex ratio in five species from south and southeast coast of India varied remarkably. Five species were selected for the present investigation. Range in the percentage of males was from 8 to 121 in @iUndinula vulgaris@@ (Dana), 16-425 in @i...

  19. Sex Ratios, Economic Power, and Women's Roles: A Theoretical Extension and Empirical Test.

    Science.gov (United States)

    South, Scott J.

    1988-01-01

    Tested hypotheses concerning sex ratios, women's roles, and economic power with data from 111 countries. Found undersupply of women positively associated with proportion of women who marry and fertility rate; inversely associated with women's average age at marriage, literacy rate, and divorce rate. Suggests women's economic power may counteract…

  20. Lunar cycles at mating do not influence sex ratio at birth in horses.

    Science.gov (United States)

    Aguilar, J J; Cuervo-Arango, J; Santa Juliana, L

    2015-02-01

    It is scientifically demonstrated that lunar cycles have important effects on several biological events. Controversy exists about the lunar influence on human and animal parturition. In addition, in the horse industry, especially in Polo Horse breeders of Argentina and around the world there is a higher demand for female offspring than for males. The objective of this study was to determine whether there is a significant association between the lunar phase at the time of mating and the sex ratio at birth in horses. The Argentinean Stud Book provided information related to all matings registered for Thoroughbred and Arab horses between 2003 and 2011. Statistical associations were tested between dates of matings at different lunar phases or days and sex ratio at birth. A total of 65.535 gestations were studied. Overall, sex ratio at birth resulted in 33.396 fillies (50.96%) and 32.139 colts (49.04%). The percentages of males and females at birth were not statistically different amongst the different lunar phases or days. We can strongly conclude that managing the breeding dates in relation to lunar cycles in order to manipulate the sex ratio of the offspring is not a viable option in horses.

  1. Sex-Ratio and Gender Differences in Depression in an Unselected Adult Population.

    Science.gov (United States)

    Baumgart, E. P.; Oliver, J. M.

    1981-01-01

    Neither sex-ratio nor gender differences in depression were found in adult sample, similar to pattern found among university students. No demographic variable was correlated significantly with depression. Suggests results may be due to the elimination of face-to-face interviews, which expose males to greater negative repercussions for exhibiting…

  2. The paternal-sex-ratio (PSR) chromosome in natural populations of Nasonia (Hymenoptera Chalcidoidea)

    NARCIS (Netherlands)

    Beukeboom, L.W.; Werren, J.H.

    2000-01-01

    Selfish genetic elements may be important in promoting evolutionary change. Paternal sex ratio (PSR) is a selfish B chromosome that causes all-male families in the haplodiploid parasitic wasp Nasonia vitripennis, by inducing paternal genome loss in fertilized eggs. The natural distribution and

  3. Seasonal Sex Ratio Trend in the European Kestrel : An Evolutionarily Stable Strategy Analysis

    NARCIS (Netherlands)

    Pen, I.R.; Weissing, F.J.; Daan, S.

    We present an evolutionarily stable strategy (ESS) model to analyze selection on seasonal variation in the brood sex ratio, as observed in several species of raptorial birds. The model is specifically tailored to the life history of the European kestrel, and it reflects the maturation time

  4. Female starlings adjust primary sex ratio in response to aromatic plants in the nest.

    Science.gov (United States)

    Polo, Vicente; Veiga, José P; Cordero, Pedro J; Viñuela, Javier; Monaghan, Pat

    2004-09-22

    Adjustment of offspring sex ratios should be favoured by natural selection when parents are capable of facultatively altering brood sex ratios and of recognizing the circumstances that predict the probable fitness benefit of producing sons and daughters. Although experimental studies have shown that female birds may adjust offspring sex ratios in response to changes in their own condition and in the external appearance of their mate, and male attributes other than his external morphology are also thought to act as signals of male quality, it is not known whether females will respond to changes in such signals, in the absence of any change in the appearance of the male himself. Here, we experimentally manipulated a male courtship display, the green plants carried to the nest by male spotless starlings (Sturnus unicolor), without changing any physical attributes of the male himself, and examined whether this influenced female decisions on offspring sex ratio. We found that in an environment in which female starlings were producing more daughters than sons, experimental enhancement of the green nesting material caused females to significantly increase the number of male eggs produced and thereby removed the female bias. This effect was consistent in 2 years and at two localities. This demonstrates that the green material, whose function has long puzzled biologists, conveys important information to the female and that she facultatively adjusts offspring production accordingly.

  5. Sex ratio at birth and racial differences: Why do Black women give ...

    African Journals Online (AJOL)

    The two important questions that this paper will attempt to answer are: (1) why is it that regardless of race/ethnicity or geographic location, the sex ratio data at birth show more males than females?; and (2) Why is it that regardless of geographic location compared to other racial/ethnic groups, Black women or Women of ...

  6. Changes in the sex ratio of the Common Pochard Aythya ferina in Europe and North Africa

    NARCIS (Netherlands)

    Brides, Kane; Wood, Kevin; Hearn, Richard; Fijen, T.P.M.

    2017-01-01

    Assessments of the sex ratio among Common Pochard Aythya ferina flocks were undertaken in countries across Europe and into North Africa in January 2016, for comparison with results from surveys carried out over the same area in January 1989 and January 1990. The mean (± 95% CI) proportions of males

  7. Sex-ratio biasing towards daughters among lower-ranking co-wives in Rwanda

    NARCIS (Netherlands)

    Pollet, Thomas V.; Fawcett, Tim W.; Buunk, Abraham P.; Nettle, Daniel

    2009-01-01

    There is considerable debate as to whether human females bias the sex ratio of their offspring as a function of their own condition. We apply the Trivers-Willard prediction-that mothers in poor condition will overproduce daughters-to a novel measure of condition, namely wife rank within a polygynous

  8. The sex ratio of offspring is associated with the mothers' age at menarche

    DEFF Research Database (Denmark)

    Fukuda, Misao; Fukuda, Kiyomi; Shimizu, Takashi

    2011-01-01

    BACKGROUND Early menarcheal age is a risk factor for breast and ovarian cancers and is also associated with an increased spontaneous abortion rate. The aim of this study was to investigate whether there is a link between early menarcheal age and the offspring sex ratio. METHODS We recorded the sex...... of 21208 live born infants, all singletons, born to 10 847 premenopausal women (mean attending age: 37.5 ± 7.2 years, range 22-54) who attended our clinics for obstetrical and gynaecological assessment. We calculated the sex ratio of newborn infants in relation to the mothers' age of menarche (from 9 to 18...... years) and to the number of infants per woman (i.e. fertility index). RESULTS A low offspring sex ratio (males/females) of 0.800 was observed in mothers who entered menarche at the age of 9 years; the odds ratio (OR) (95% confidence intervals) compared with those of control group with menarche at age 14...

  9. Recurrent selection on the Winters sex-ratio genes in Drosophila simulans.

    Science.gov (United States)

    Kingan, Sarah B; Garrigan, Daniel; Hartl, Daniel L

    2010-01-01

    Selfish genes, such as meiotic drive elements, propagate themselves through a population without increasing the fitness of host organisms. X-linked (or Y-linked) meiotic drive elements reduce the transmission of the Y (X) chromosome and skew progeny and population sex ratios, leading to intense conflict among genomic compartments. Drosophila simulans is unusual in having a least three distinct systems of X chromosome meiotic drive. Here, we characterize naturally occurring genetic variation at the Winters sex-ratio driver (Distorter on the X or Dox), its progenitor gene (Mother of Dox or MDox), and its suppressor gene (Not Much Yang or Nmy), which have been previously mapped and characterized. We survey three North American populations as well as 13 globally distributed strains and present molecular polymorphism data at the three loci. We find that all three genes show signatures of selection in North America, judging from levels of polymorphism and skews in the site-frequency spectrum. These signatures likely result from the biased transmission of the driver and selection on the suppressor for the maintenance of equal sex ratios. Coalescent modeling indicates that the timing of selection is more recent than the age of the alleles, suggesting that the driver and suppressor are coevolving under an evolutionary "arms race." None of the Winters sex-ratio genes are fixed in D. simulans, and at all loci we find ancestral alleles, which lack the gene insertions and exhibit high levels of nucleotide polymorphism compared to the derived alleles. In addition, we find several "null" alleles that have mutations on the derived Dox background, which result in loss of drive function. We discuss the possible causes of the maintenance of presence-absence polymorphism in the Winters sex-ratio genes.

  10. Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury

    DEFF Research Database (Denmark)

    Timmermann, Clara Amalie Gade; Choi, Anna L.; Petersen, Maria Skaalum

    2017-01-01

    This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective...... data from three Faroese birth cohorts, with a total of 2,152 healthy mother-child dyads recruited between 1986 and 2009. The Faroe Islands is a subarctic fishing community, where pilot whale meat and blubber are part of the traditional marine diet. Exposures were measured in maternal hair, serum...... or umbilical cord blood. Confounder adjusted logistic regression models were used to assess the associations between maternal exposures and the secondary sex ratio. A doubling in ΣPCB, p,p'-DDE and mercury concentrations were associated with increased odds by 8% (95% CI = 0-16%), 7% (95% CI = 0-14%) and 9% (95...

  11. Sex differences in neuromuscular function after repeated eccentric contractions of the knee extensor muscles.

    Science.gov (United States)

    Lee, Andrea; Baxter, Jake; Eischer, Claire; Gage, Matt; Hunter, Sandra; Yoon, Tejin

    2017-06-01

    This study examined the mechanisms for force and power reduction during and up to 48 h after maximal eccentric contractions of the knee extensor muscles in young men and women. 13 men (22.8 ± 2.6 years) and 13 women (21.6 ± 2.2 years) performed 150 maximal effort eccentric contractions (5 sets of 30) with the knee extensor muscles at 60° s -1 . Maximal voluntary isometric contractions (MVIC) and maximal voluntary concentric contractions (MVCC) were performed before and after the 150 eccentric contractions. The MVCCs involved a set of two isokinetic contractions at 60° s -1 and sets of isotonic contractions performed at seven different resistance loads (1 N m, 10, 20, 30, 40, 50, and 60% MVIC). Electrical stimulation was used during the MVICs and at rest to determine changes in voluntary activation and contractile properties. At baseline, men were stronger than women (MVIC: 276 ± 48 vs. 133 ± 37 N m) and more powerful (MVCC: 649 ± 77 vs. 346 ± 78 W). At termination of the eccentric contractions, voluntary activation, resting twitch amplitude, and peak power during concentric contractions at the seven loads and at 60° s -1 decreased (P  0.05) with no sex differences. Central mechanisms were primarily responsible for the depressed maximal force production up to 48 h after repeated eccentric contractions of the knee extensors and these mechanisms were similar in men and women.

  12. Sex-Specific Arrival Times on the Breeding Grounds: Hybridizing Migratory Skuas Provide Empirical Support for the Role of Sex Ratios.

    Science.gov (United States)

    Lisovski, Simeon; Fröhlich, Anne; von Tersch, Matthew; Klaassen, Marcel; Peter, Hans-Ulrich; Ritz, Markus S

    2016-04-01

    In migratory animals, protandry (earlier arrival of males on the breeding grounds) prevails over protogyny (females preceding males). In theory, sex differences in timing of arrival should be driven by the operational sex ratio, shifting toward protogyny in female-biased populations. However, empirical support for this hypothesis is, to date, lacking. To test this hypothesis, we analyzed arrival data from three populations of the long-distance migratory south polar skua (Catharacta maccormicki). These populations differed in their operational sex ratio caused by the unidirectional hybridization of male south polar skuas with female brown skuas (Catharacta antarctica lonnbergi). We found that arrival times were protandrous in allopatry, shifting toward protogyny in female-biased populations when breeding in sympatry. This unique observation is consistent with theoretical predictions that sex-specific arrival times should be influenced by sex ratio and that protogyny should be observed in populations with female-biased operational sex ratio.

  13. National, regional, and global sex ratios of infant, child, and under-5 mortality and identification of countries with outlying ratios: a systematic assessment.

    Science.gov (United States)

    Alkema, Leontine; Chao, Fengqing; You, Danzhen; Pedersen, Jon; Sawyer, Cheryl C

    2014-09-01

    Under natural circumstances, the sex ratio of male to female mortality up to the age of 5 years is greater than one but sex discrimination can change sex ratios. The estimation of mortality by sex and identification of countries with outlying levels is challenging because of issues with data availability and quality, and because sex ratios might vary naturally based on differences in mortality levels and associated cause of death distributions. For this systematic analysis, we estimated country-specific mortality sex ratios for infants, children aged 1-4 years, and children under the age of 5 years (under 5s) for all countries from 1990 (or the earliest year of data collection) to 2012 using a Bayesian hierarchical time series model, accounting for various data quality issues and assessing the uncertainty in sex ratios. We simultaneously estimated the global relation between sex ratios and mortality levels and constructed estimates of expected and excess female mortality rates to identify countries with outlying sex ratios. Global sex ratios in 2012 were 1·13 (90% uncertainty interval 1·12-1·15) for infants, 0·95 (0·93-0·97) for children aged 1-5 years, and 1·08 (1·07-1·09) for under 5s, an increase since 1990 of 0·01 (-0·01 to 0·02) for infants, 0·04 (0·02 to 0·06) for children aged 1-4 years, and 0·02 (0·01 to 0·04) for under 5s. Levels and trends varied across regions and countries. Sex ratios were lowest in southern Asia for 1990 and 2012 for all age groups. Highest sex ratios were seen in developed regions and the Caucasus and central Asia region. Decreasing mortality was associated with increasing sex ratios, except at very low infant mortality, where sex ratios decreased with total mortality. For 2012, we identified 15 countries with outlying under-5 sex ratios, of which ten countries had female mortality higher than expected (Afghanistan, Bahrain, Bangladesh, China, Egypt, India, Iran, Jordan, Nepal, and Pakistan). Although excess female

  14. Masculine sex ratios, population age structure and the potential spread of HIV in China

    Directory of Open Access Journals (Sweden)

    M. Giovanna Merli

    2010-01-01

    Full Text Available There is much speculation regarding the contribution of China's changing demography to the spread of HIV/AIDS. We employ a bio-behavioral macrosimulation model of the heterosexual spread of HIV/AIDS to evaluate the roles that China's unique demographic conditions -- (1 masculine sex ratios at birth and (2 a population age structure that reflects rapid fertility decline since the 1970's -- play in altering the market for sexual partners, thereby potentially fueling an increase in behaviors associated with greater risk of HIV infection. We first simulate the relative contributions of the sex ratio at birth and the population age structure to the oversupply of males in the market for sexual partners and show that the sex ratio at birth only aggravates the severe oversupply of males which is primarily a consequence of the population age structure. We then examine the potential consequences of this demographic distortion for the spread of HIV infection and show that, to the extent that males adapt to the dearth of suitable female partners by seeking unprotected sexual contacts with female sex workers, the impact of the oversupply of males in the sexual partnership market on the spread of HIV will be severe.

  15. Transgenerational plasticity mitigates the impact of global warming to offspring sex ratios.

    Science.gov (United States)

    Donelson, Jennifer M; Munday, Philip L

    2015-08-01

    Global warming poses a threat to organisms with temperature-dependent sex determination because it can affect operational sex ratios. Using a multigenerational experiment with a marine fish, we provide the first evidence that parents developing from early life at elevated temperatures can adjust their offspring gender through nongenetic and nonbehavioural means. However, this adjustment was not possible when parents reproduced, but did not develop, at elevated temperatures. Complete restoration of the offspring sex ratio occurred when parents developed at 1.5 °C above the present-day average temperature for one generation. However, only partial improvement in the sex ratio occurred at 3.0 °C above average conditions, even after two generations, suggesting a limitation to transgenerational plasticity when developmental temperature is substantially increased. This study highlights the potential for transgenerational plasticity to ameliorate some impacts of climate change and that development from early life may be essential for expression of transgenerational plasticity in some traits. © 2015 John Wiley & Sons Ltd.

  16. Causes and consequences of adult sex ratio imbalance in a historical U.S. population.

    Science.gov (United States)

    Schacht, Ryan; Smith, Ken R

    2017-09-19

    The responsiveness of individuals to partner availability has been well-documented across the literature. However, there is disagreement regarding the direction of the consequences of sex ratio imbalance. Specifically, does an excess of males or females promote male-male mating competition? In an attempt to clarify the role of the adult sex ratio (ASR) on behaviour, here we evaluate both competing and complimentary expectations derived from theory across the social and biological sciences. We use data drawn from a historical, nineteenth century population in North America and target several life-history traits thought to be affected by partner availability: age at first birth, relationship status, completed fertility and longevity. Furthermore, we assess the role of various contributors to a population's ASR. We find that both the contributors to and consequences of sex ratio imbalance vary over time. Our results largely support predictions of greater male pairbond commitment and lesser male mating effort, as well as elevated bargaining power of women in response to female scarcity. After reviewing our findings, and others from across the literature, we highlight the need to adjust predictions in response to ASR imbalance by the: (i) culturally mediated mating arena, (ii) variable role of demographic inputs across time and place, (iii) constraints to behavioural outcomes across populations, and (iv) ability and accuracy of individuals to assess partner availability.This article is part of the themed issue 'Adult sex ratios and reproductive strategies: a critical re-examination of sex differences in human and animal societies'. © 2017 The Author(s).

  17. Thermal fluctuation within nests and predicted sex ratio of Morelet's Crocodile.

    Science.gov (United States)

    Escobedo-Galván, Armando H; López-Luna, Marco A; Cupul-Magaña, Fabio G

    2016-05-01

    Understanding the interplay between thermal variations and sex ratio in reptiles with temperature-dependent sex determination is the first step for developing long-term conservation strategies. In case of crocodilians, the information is fragmentary and insufficient for establishing a general framework to consider how thermal fluctuation influence sex determination under natural conditions. The main goal of this study was to analyze thermal variation in nests of Crocodylus moreletii and to discuss the potential implications for predicting offspring sex ratio. The study was carried out at the Centro de Estudios Tecnológicos del Mar N° 2 and at the Sistemas Productivos Cocodrilo, Campeche, Mexico. Data was collected in the nesting season of Morelet's Crocodiles during three consecutive seasons (2007-2009). Thermal fluctuations for multiple areas of the nest chamber were registered by data loggers. We calculate the constant temperature equivalent based on thermal profiles among nests to assess whether there are differences between the nest temperature and its equivalent to constant temperature. We observed that mean nest temperature was only different among nests, while daily thermal fluctuations vary depending on the depth position within the nest chamber, years and nests. The constant temperature equivalent was different among and within nests, but not among survey years. We observed differences between constant temperature equivalent and mean nest temperature both at the top and in the middle of the nest cavities, but were not significantly different at the bottom of nest cavities. Our results enable examine and discuss the relevance of daily thermal fluctuations to predict sex ratio of the Morelet's Crocodile. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Sex Ratio and Twinning in Women with Hyperemesis or Pre-eclampsia

    DEFF Research Database (Denmark)

    Basso, Olga; Olsen, Jørn

    2001-01-01

    We examined twinning and fetal gender in births of women with a hospital diagnosis of pre-eclampsia or hyperemesis. We also investigated sex ratio in infants whose mothers had had hyperemesis or pre-eclampsia in a different pregnancy. From all the hospitalized cases in Denmark between 1980 and 1996...... we extracted 6,227 births with hyperemesis and 24,764 with pre-eclampsia. Twins were more frequent in pregnancies with either condition. The male to female sex ratio was 1.04 (95%CI = 1.02-1.05) in the reference population, 0.87 (95% CI = 0.82-0.91) in births with hyperemesis, and 1.10 (95% CI = 1...

  19. Common vole (Microtus arvalis) population sex ratio: biases and process variation

    Czech Academy of Sciences Publication Activity Database

    Bryja, Josef; Nesvadbová, Jiřina; Heroldová, Marta; Jánová, Eva; Losík, J.; Trebatická, L.; Tkadlec, Emil

    2005-01-01

    Roč. 83, č. 11 (2005), s. 1391-1399 ISSN 0008-4301 R&D Projects: GA ČR(CZ) GA524/01/1316; GA ČR(CZ) GP206/02/P068; GA ČR(CZ) GA206/04/2003 Institutional research plan: CEZ:AV0Z60930519 Keywords : common vole * population sex ratio Subject RIV: EH - Ecology, Behaviour Impact factor: 1.175, year: 2005

  20. Explaining the Rapid Increase in Nigeria's Sex Ratio at Birth: Factors and Implications.

    Science.gov (United States)

    Kaba, Amadu J

    2015-06-01

    This paper examines the rapid increase in Nigeria's sex ratio at birth from 1.03 boys born for every 1 girl born in each year from 1996-2008 to 1.06 in each year from 2009-2014, second only to Tunisia in Africa at 1.07. The average sex ratio at birth in the world in 2014 was 1.07. In most Black African nations or Black majority nations, it is 1.03 or less. Among the factors presented for this development are: historical fluctuations of sex ratio at birth; geography and ethnicity; male preference/chasing a son; Age of parents; high death rates of male infants and males in general; and wealth/socioeconomic status. Among the potential implications are: young and poor men in Nigeria may not be able to find brides and form families due to a potential shortage of females; emigration of young and poor Nigerian men to West (Africa) and elsewhere to seek brides and form families; immigration of marriage age women from West (Africa) and around the world to Nigeria to seek husbands; and low contraceptive use and high fertility rates in Nigeria.

  1. Sex ratio meiotic drive as a plausible evolutionary mechanism for hybrid male sterility.

    Directory of Open Access Journals (Sweden)

    Linbin Zhang

    2015-03-01

    Full Text Available Biological diversity on Earth depends on the multiplication of species or speciation, which is the evolution of reproductive isolation such as hybrid sterility between two new species. An unsolved puzzle is the exact mechanism(s that causes two genomes to diverge from their common ancestor so that some divergent genes no longer function properly in the hybrids. Here we report genetic analyses of divergent genes controlling male fertility and sex ratio in two very young fruitfly species, Drosophila albomicans and D. nasuta. A majority of the genetic divergence for both traits is mapped to the same regions by quantitative trait loci mappings. With introgressions, six major loci are found to contribute to both traits. This genetic colocalization implicates that genes for hybrid male sterility have evolved primarily for controlling sex ratio. We propose that genetic conflicts over sex ratio may operate as a perpetual dynamo for genome divergence. This particular evolutionary mechanism may largely contribute to the rapid evolution of hybrid male sterility and the disproportionate enrichment of its underlying genes on the X chromosome--two patterns widely observed across animals.

  2. WormGender - Open-Source Software for Automatic Caenorhabditis elegans Sex Ratio Measurement.

    Directory of Open Access Journals (Sweden)

    Marta K Labocha

    Full Text Available Fast and quantitative analysis of animal phenotypes is one of the major challenges of current biology. Here we report the WormGender open-source software, which is designed for accurate quantification of sex ratio in Caenorhabditis elegans. The software functions include, i automatic recognition and counting of adult hermaphrodites and males, ii a manual inspection feature that enables manual correction of errors, and iii flexibility to use new training images to optimize the software for different imaging conditions. We evaluated the performance of our software by comparing manual and automated assessment of sex ratio. Our data showed that the WormGender software provided overall accurate sex ratio measurements. We further demonstrated the usage of WormGender by quantifying the high incidence of male (him phenotype in 27 mutant strains. Mutants of nine genes (brc-1, C30G12.6, cep-1, coh-3, him-3, him-5, him-8, skr-1, unc-86 showed significant him phenotype. The WormGender is written in Java and can be installed and run on both Windows and Mac platforms. The source code is freely available together with a user manual and sample data at http://www.QuantWorm.org/. The source code and sample data are also available at http://dx.doi.org/10.6084/m9.figshare.1541248.

  3. Ownership of dwelling affects the sex ratio at birth in Uganda.

    Directory of Open Access Journals (Sweden)

    Bernard Wallner

    Full Text Available BACKGROUND: Socio-economic conditions can affect the secondary sex ratio in humans. Mothers under good environmental conditions are predicted to increase the birth rates of sons according to the Trivers-Willard hypothesis (TWH. This study analyzed the effects of ownership and non-ownership of dwellings on the sex ratio at birth (SRB on a Ugandan sample. METHODOLOGY/PRINCIPAL FINDINGS: Our investigation included 438,640 mothers aged between 12 and 54 years. The overall average SRB was 0.5008. Mothers who live in owned dwellings gave increased births to sons (0.5019 compared to those who live in non-owned dwellings (0.458. Multivariate statistics revealed the strongest effects of dwelling ownership when controlling for demographic and social variables such as marital status, type of marriage, mothers' age, mothers' education, parity and others. CONCLUSIONS/SIGNIFICANCE: The results are discussed in the framework of recent plausible models dealing with the adjustment of the sex ratio. We conclude that the aspect of dwelling status could represent an important socio-economic parameter in relation to SRB variations in humans if further studies are able to analyze it between different countries in a comparative way.

  4. Ownership of dwelling affects the sex ratio at birth in Uganda.

    Science.gov (United States)

    Wallner, Bernard; Fieder, Martin; Seidler, Horst

    2012-01-01

    Socio-economic conditions can affect the secondary sex ratio in humans. Mothers under good environmental conditions are predicted to increase the birth rates of sons according to the Trivers-Willard hypothesis (TWH). This study analyzed the effects of ownership and non-ownership of dwellings on the sex ratio at birth (SRB) on a Ugandan sample. Our investigation included 438,640 mothers aged between 12 and 54 years. The overall average SRB was 0.5008. Mothers who live in owned dwellings gave increased births to sons (0.5019) compared to those who live in non-owned dwellings (0.458). Multivariate statistics revealed the strongest effects of dwelling ownership when controlling for demographic and social variables such as marital status, type of marriage, mothers' age, mothers' education, parity and others. The results are discussed in the framework of recent plausible models dealing with the adjustment of the sex ratio. We conclude that the aspect of dwelling status could represent an important socio-economic parameter in relation to SRB variations in humans if further studies are able to analyze it between different countries in a comparative way.

  5. Sex ratio meiotic drive as a plausible evolutionary mechanism for hybrid male sterility.

    Science.gov (United States)

    Zhang, Linbin; Sun, Tianai; Woldesellassie, Fitsum; Xiao, Hailian; Tao, Yun

    2015-03-01

    Biological diversity on Earth depends on the multiplication of species or speciation, which is the evolution of reproductive isolation such as hybrid sterility between two new species. An unsolved puzzle is the exact mechanism(s) that causes two genomes to diverge from their common ancestor so that some divergent genes no longer function properly in the hybrids. Here we report genetic analyses of divergent genes controlling male fertility and sex ratio in two very young fruitfly species, Drosophila albomicans and D. nasuta. A majority of the genetic divergence for both traits is mapped to the same regions by quantitative trait loci mappings. With introgressions, six major loci are found to contribute to both traits. This genetic colocalization implicates that genes for hybrid male sterility have evolved primarily for controlling sex ratio. We propose that genetic conflicts over sex ratio may operate as a perpetual dynamo for genome divergence. This particular evolutionary mechanism may largely contribute to the rapid evolution of hybrid male sterility and the disproportionate enrichment of its underlying genes on the X chromosome--two patterns widely observed across animals.

  6. Ownership of Dwelling Affects the Sex Ratio at Birth in Uganda

    Science.gov (United States)

    Wallner, Bernard; Fieder, Martin; Seidler, Horst

    2012-01-01

    Background Socio-economic conditions can affect the secondary sex ratio in humans. Mothers under good environmental conditions are predicted to increase the birth rates of sons according to the Trivers-Willard hypothesis (TWH). This study analyzed the effects of ownership and non-ownership of dwellings on the sex ratio at birth (SRB) on a Ugandan sample. Methodology/Principal Findings Our investigation included 438,640 mothers aged between 12 and 54 years. The overall average SRB was 0.5008. Mothers who live in owned dwellings gave increased births to sons (0.5019) compared to those who live in non-owned dwellings (0.458). Multivariate statistics revealed the strongest effects of dwelling ownership when controlling for demographic and social variables such as marital status, type of marriage, mothers’ age, mothers’ education, parity and others. Conclusions/Significance The results are discussed in the framework of recent plausible models dealing with the adjustment of the sex ratio. We conclude that the aspect of dwelling status could represent an important socio-economic parameter in relation to SRB variations in humans if further studies are able to analyze it between different countries in a comparative way. PMID:23284697

  7. How do sex ratios in China influence marriage decisions and intra-household resource allocation?

    Science.gov (United States)

    Porter, Maria

    2016-06-01

    This article examines how imbalanced sex ratios influence marriage decisions and household bargaining. Using data from the 1982 Chinese census, the traditional "availability ratio" is modified to reflect the degree to which men tend to marry women from different cohorts. This ratio reflects the average tendency of men to prefer women who are close in age to women who are several years younger than them by weighting cohort sizes using the proportion of people in the population who marry someone born in a different cohort. Given that men generally marry younger women, this ratio varies independently of the size of one's own birth cohort. Yet, the ratio fluctuates considerably across individuals, as the sizes of birth cohorts in China vary across time and regions. This enables us to examine how variability in such ratios may influence marriage decisions and household bargaining. The findings suggest that women exercise greater bargaining power once married. Results indicate that as women become scarcer in the marriage market, they have healthier sons. Men also delay marriage, and consume less tobacco and alcohol. This paper also highlights how sensitive findings may be to using this modified weighted availability ratio rather than a traditional unweighted availability ratio.

  8. Flow cytometric sexing of spider sperm reveals an equal sperm production ratio in a female-biased species

    DEFF Research Database (Denmark)

    Vanthournout, Bram; Deswarte, K; Hammad, H

    2014-01-01

    research. Pinpointing the underlying mechanism of sex ratio bias is challenging owing to the multitude of potential sex ratio-biasing factors. In the dwarf spider, Oedothorax gibbosus, infection with the bacterial endosymbiont Wolbachia results in a female bias. However, pedigree analysis reveals...

  9. Effect of Corticosterone and Hen Body Mass on Primary Sex Ratio in Laying Hen (Gallusgallus), Using Unincubated Eggs1

    NARCIS (Netherlands)

    Aslam, M.A.; Groothuis, T.G.G.; Smits, M.A.; Woelders, H.

    2014-01-01

    In various studies, chronic elevation of corticosterone levels in female birds under natural or experimental conditions resulted in female biased offspring sex ratios. In chicken, one study with injected corticosterone resulted in a male sex ratio bias. In the current study, we chronically elevated

  10. Effect of corticosterone and hen body mass on primary sex ratio in laying hen (Gallus gallus), using unincubated eggs

    NARCIS (Netherlands)

    Aslam, Muhammad Aamir; Groothuis, Ton G. G.; Smits, Mari A.; Woelders, Henri

    In various studies, chronic elevation of corticosterone levels in female birds under natural or experimental conditions resulted in female biased offspring sex ratios. In chicken, one study with injected corticosterone resulted in a male sex ratio bias. In the current study, we chronically elevated

  11. Sex pheromone component ratios and mating isolation among three Lygus plant bug species of North America

    Science.gov (United States)

    Byers, John A.; Fefer, Daniela; Levi-Zada, Anat

    2013-12-01

    The plant bugs Lygus hesperus, Lygus lineolaris, and Lygus elisus (Hemiptera: Miridae) are major pests of many agricultural crops in North America. Previous studies suggested that females release a sex pheromone attractive to males. Other studies showed that males and females contain microgram amounts of ( E)-4-oxo-2-hexenal, hexyl butyrate, and ( E)-2-hexenyl butyrate that are emitted as a defense against predators. Using gas chromatography-mass spectrometry, we found that female L. lineolaris and L. elisus have a 4:10 ratio of hexyl butyrate to ( E)-2-hexenyl butyrate that is reversed from the 10:1 ratio in female L. hesperus (males of the three species have ~10:1 ratio). These reversed ratios among females of the species suggest a behavioral role. Because both sexes have nearly equal amounts of the major volatiles, females should release more to attract males. This expectation was supported because L. hesperus females released more hexyl butyrate (mean of 86 ng/h) during the night (1800-0700 hours) than did males (pheromone component for all three species, ( E)-2-hexenyl butyrate is essential for L. elisus and L. lineolaris, and hexyl butyrate is essential for L. hesperus. However, all three components are recognized by each species since ratios of the butyrate esters are critical for conspecific attraction and heterospecific avoidance by males and thus play a role in reproductive isolation among the three species. Because L. hesperus males and females are known to emit these major volatiles for repelling ant predators, our study links defensive allomones in Lygus bugs with an additional use as sex pheromones.

  12. Spatio-temporal variation in the incubation duration and sex ratio of hawksbill hatchlings: implication for future management.

    Science.gov (United States)

    dei Marcovaldi, Maria A G; Santos, Armando J B; Santos, Alexsandro S; Soares, Luciano S; Lopez, Gustave G; Godfrey, Matthew H; López-Mendilaharsu, Milagros; Fuentes, Mariana M P B

    2014-08-01

    Climate change poses a unique threat to species with temperature dependent sex determination (TSD), such as marine turtles, where increases in temperature can result in extreme sex ratio biases. Knowledge of the primary sex ratio of populations with TSD is key for providing a baseline to inform management strategies and to accurately predict how future climate changes may affect turtle populations. However, there is a lack of robust data on offspring sex ratio at appropriate temporal and spatial scales to inform management decisions. To address this, we estimate the primary sex ratio of hawksbill hatchlings, Eretmochelys imbricata, from incubation duration of 5514 in situ nests from 10 nesting beaches from two regions in Brazil over the last 27 years. A strong female bias was estimated in all beaches, with 96% and 89% average female sex ratios produced in Bahia (BA) and Rio Grande do Norte (RN). Both inter-annual (BA, 88 to 99%; RN, 75 to 96% female) and inter-beach (BA, 92% to 97%; RN, 81% to 92% female) variability in mean offspring sex ratio was observed. These findings will guide management decisions in Brazil and provide further evidence of highly female-skew sex ratios in hawksbill turtles. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Exposure to widespread environmental endocrine disrupting chemicals and human sperm sex ratio

    International Nuclear Information System (INIS)

    Jurewicz, Joanna; Radwan, Michał; Sobala, Wojciech; Radwan, Paweł; Jakubowski, Lucjusz; Wielgomas, Bartosz; Ligocka, Danuta; Brzeźnicki, Sławomir; Hanke, Wojciech

    2016-01-01

    In recent years, a trend toward a declining proportion of male births has been noted in several, but not all, industrialized countries. The underlying reason for the drop in the sex ratio is unclear, but one theory states that widespread environmental endocrine disrupting chemicals affecting the male reproductive system in a negative manner could be part of the explanation. The present study was designed to investigate whether the urinary phthalate, pyrethroids and polycyclic aromatic hydrocarbons metabolites concentrations were associated with sperm Y:X ratio. The study population consisted of 194 men aged under 45 years of age who attended infertility clinic in Lodz, Poland for diagnostic purposes with normal semen concentration of 20–300 mln/ml or with slight oligozoospermia (semen concentration of 15–20 mln/ml) (WHO, 1999). The Y:X ratio was assessed by fluorescent in situ hybridization. Urinary concentrations of 1-hydroxypyrene were measured by high performance liquid chromatography, phthalate metabolites were analyzed using a procedure based on the LC-MS/MS methods and metabolites of synthetic pyrethroids were assessed by gas chromatography ion-tap mass spectrometry method. After adjustment for potential confounders (past diseases, age, abstinence, smoking, alcohol consumption, sperm concentration, motility, morphology) 5OH MEHP, CDCCA to TDCCA and 1-OHP was negatively related to Y:X sperm chromosome ratio (p = 0.033, p < 0.001, p = 0.047 respectively). As this is the first study to elucidate the association between the level of metabolites of widespread environmental endocrine disrupting chemicals (phthalates, synthetic pyrethroids, polycyclic aromatic hydrocarbons) on sex chromosome ratio in sperm therefore, these findings require further replication in other populations. - Highlights: • Urinary phthalate metabolites levels were significantly associated with a decrease in Y/X chromosome bearing sperm. • The levels of 1-hydroxypyrene in urine

  14. Mixture Analysis and Mammalian Sex Ratio Among Middle Pleistocene Mouflon of Arago Cave, France

    Science.gov (United States)

    Monchot, Hervé

    1999-09-01

    In archaeological studies, it is often important to be able assess sexual dimorphism and sex ratios in populations. Obtaining sex ratio is easy if each individual in the population can be accurately sexed through the use of one more objective variables. But this is often impossible, due to incompleteness of the osteological record. A modern statistical approach to handle this problem is Mixture Analysis using the method of maximum likelihood. It consists of determining how many groups are present in the sample, two in this case, in which proportions they occur, and to estimate the parameters accordingly. This paper shows the use of this method on vertebrate fossil populations in a prehistoric context with implications on prey acquisition by early humans. For instance, the analysis of mouflon bones from Arago cave (Tautavel, France) indicates that there are more females than males in the F layer. According to the ethology of the animal, this indicates that the hunting strategy could be the result of selective choice of the prey. Moreover, we may deduce the presence of Anteneandertalians on the site during spring and summer periods.

  15. Calcium availability influences litter size and sex ratio in white-footed mice (Peromyscus leucopus.

    Directory of Open Access Journals (Sweden)

    Christina M Schmidt

    Full Text Available The production of offspring typically requires investment of resources derived from both the environment and maternal somatic reserves. As such, the availability of either of these types of resources has the potential to limit the degree to which resources are allocated to reproduction. Theory and empirical studies have argued that mothers modify reproductive performance relative to exogenous resource availability and maternal condition by adjusting size, number or sex of offspring produced. These relationships have classically been defined relative to availability of energy sources; however, in vertebrates, calcium also plays a critical role in offspring production, as a considerable amount of calcium is required to support the development of offspring skeleton(s. We tested whether the availability of calcium influences reproductive output by providing female white-footed mice with a low-calcium or standard diet from reproductive maturity to senescence. We then compared maternal skeletal condition and reproductive output, based on offspring mass, offspring number and litter sex ratio, between dietary treatments. Mothers on the low-calcium diet exhibited diminished skeletal condition at senescence and produced smaller and strongly female-biased litters. We show that skeletal condition and calcium intake can influence sex ratio and reproductive output following general theoretical models of resource partitioning during reproduction.

  16. Influence of sex on performance fatigability of the plantar flexors following repeated maximal dynamic shortening contractions.

    Science.gov (United States)

    Lanning, Amelia C; Power, Geoffrey A; Christie, Anita D; Dalton, Brian H

    2017-10-01

    The purpose was to determine sex differences in fatigability during maximal, unconstrained velocity, shortening plantar flexions. The role of time-dependent measures (i.e., rate of torque development, rate of velocity development, and rate of neuromuscular activation) in such sex-related differences was also examined. By task termination, females exhibited smaller reductions in power and similar changes in rate of neuromuscular activation than males, indicating females were less fatigable than males.

  17. Establishing sex ratios of sea turtle foraging populations: validation of a novel testosterone hormone assay technology and sex assessment for five species.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Demographic data are essential for developing sound management and conservation plans for marine turtle populations. Sex ratios, even though they are an essential...

  18. Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio

    Directory of Open Access Journals (Sweden)

    Přemysl Mikula

    2009-01-01

    Full Text Available The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio. Experimental juvenile zebrafish (20 days post hatching were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17β-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.

  19. Juvenile exposure to vinclozolin shifts sex ratios and impairs reproductive capacity of zebrafish.

    Science.gov (United States)

    Lor, Yer; Revak, Andrew; Weigand, Jenna; Hicks, Elisabeth; Howard, David R; King-Heiden, Tisha C

    2015-12-01

    Exposure to endocrine disruptors during critical periods of development can impact the sustainability of wild fish populations. Anti-androgenic compounds have received less attention, but are capable of modulating gonad differentiation and maturation, and impairing reproduction in fish. The fungicide vinclozolin (VZ) has been shown to impair reproduction in adult fish, but less is known about its effects following exposure earlier in development. Here we show that waterborne exposure to 400μg VZ/L during critical periods of sex differentiation (21-35 days post fertilization) permanently shifts sex ratios towards females, and alters the maturation of the gonad. Both fecundity and fertility were reduced, even when oogenesis and spermatogenesis recover and sperm motility is not altered. These results demonstrate the need to better understand the impacts of early exposure to anti-androgenic compounds on fish. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Economics, cultural transmission, and the dynamics of the sex ratio at birth in China.

    Science.gov (United States)

    Lipatov, Mikhail; Li, Shuzhuo; Feldman, Marcus W

    2008-12-09

    In rural China, the ratio of newborn boys to newborn girls [sex ratio at birth (SRB)] has been rising for several decades, to values significantly above its biological norm. This trend has a number of alarming societal consequences, and has attracted the attention of scholars and politicians. The root of the problem lies in a 2,500-year-old culture of son preference. This culture is intricately linked with the economic reality of each couple's life, so that there are financial and psychological repercussions to parents who have no sons. To bring greater clarity and understanding to this issue, we present a quantitative framework that describes the interaction between economics and cultural transmission. We start with an explicit mechanism by which economic incentives can change cultural beliefs of a given individual, and go on to include a mechanism of cultural inheritance from generation to generation. We then show how economic conditions can affect the dynamics of cultural change in an entire society, and may lead to a decrease in the country's sex ratio at birth.

  1. Differences in Movement Pattern and Detectability between Males and Females Influence How Common Sampling Methods Estimate Sex Ratio.

    Directory of Open Access Journals (Sweden)

    João Fabrício Mota Rodrigues

    Full Text Available Sampling the biodiversity is an essential step for conservation, and understanding the efficiency of sampling methods allows us to estimate the quality of our biodiversity data. Sex ratio is an important population characteristic, but until now, no study has evaluated how efficient are the sampling methods commonly used in biodiversity surveys in estimating the sex ratio of populations. We used a virtual ecologist approach to investigate whether active and passive capture methods are able to accurately sample a population's sex ratio and whether differences in movement pattern and detectability between males and females produce biased estimates of sex-ratios when using these methods. Our simulation allowed the recognition of individuals, similar to mark-recapture studies. We found that differences in both movement patterns and detectability between males and females produce biased estimates of sex ratios. However, increasing the sampling effort or the number of sampling days improves the ability of passive or active capture methods to properly sample sex ratio. Thus, prior knowledge regarding movement patterns and detectability for species is important information to guide field studies aiming to understand sex ratio related patterns.

  2. Differences in Movement Pattern and Detectability between Males and Females Influence How Common Sampling Methods Estimate Sex Ratio.

    Science.gov (United States)

    Rodrigues, João Fabrício Mota; Coelho, Marco Túlio Pacheco

    2016-01-01

    Sampling the biodiversity is an essential step for conservation, and understanding the efficiency of sampling methods allows us to estimate the quality of our biodiversity data. Sex ratio is an important population characteristic, but until now, no study has evaluated how efficient are the sampling methods commonly used in biodiversity surveys in estimating the sex ratio of populations. We used a virtual ecologist approach to investigate whether active and passive capture methods are able to accurately sample a population's sex ratio and whether differences in movement pattern and detectability between males and females produce biased estimates of sex-ratios when using these methods. Our simulation allowed the recognition of individuals, similar to mark-recapture studies. We found that differences in both movement patterns and detectability between males and females produce biased estimates of sex ratios. However, increasing the sampling effort or the number of sampling days improves the ability of passive or active capture methods to properly sample sex ratio. Thus, prior knowledge regarding movement patterns and detectability for species is important information to guide field studies aiming to understand sex ratio related patterns.

  3. Preconception stress and the secondary sex ratio in a population-based preconception cohort.

    Science.gov (United States)

    Bae, Jisuk; Lynch, Courtney D; Kim, Sungduk; Sundaram, Rajeshwari; Sapra, Katherine J; Buck Louis, Germaine M

    2017-03-01

    To examine the association between preconception parental stress and the secondary sex ratio, defined as the ratio of males to females at birth. A population-based preconception cohort. Not applicable. A total of 235 couples who were enrolled before conception in Michigan and Texas between 2005 and 2009 and who had a singleton birth during the follow-up period. Couples were interviewed separately at baseline to obtain information on perceived stress (Cohen's Perceived Stress Scale) and lifetime history of physician-diagnosed anxiety and/or mood disorders. Female partners were also trained to collect basal saliva samples for the measurement of salivary stress markers, alpha-amylase and cortisol. None. Birth outcome data including infant sex were collected upon delivery. Modified Poisson regression models were used to estimate the relative risks (RRs) of a male birth for each stress marker. After adjusting for potential confounders, we observed a 76% increase in the risk of fathering a male infant (RR 1.76; 95% confidence interval 1.17-2.65) in men diagnosed with anxiety disorders compared with those who were not diagnosed. When lifetime history of physician-diagnosed anxiety disorders was modeled jointly for the couple, the association was slightly strengthened (RR 2.03; 95% confidence interval 1.46-2.84). This prospective cohort study suggests that paternal lifetime history of physician-diagnosed anxiety disorders may be associated with an increase in the secondary sex ratio, resulting in an excess of male births. Copyright © 2016 American Society for Reproductive Medicine. All rights reserved.

  4. Optimization of Sex Ratio in a Selection Plan for Palas Prolificacy Line

    Directory of Open Access Journals (Sweden)

    Răzvan Popa

    2011-05-01

    Full Text Available The aim of the paper work is to optimize the sex ratio in a selection plan, according to model developed by King (1961, which will be proposed to be applied for prolificacy improvement in Prolific Line Palas. The method used in this paper work is modeling, which exist in the most animal breeding scientifically papers. After the simulations, we observed that the most convenient variant was that which prefigure use of 13 rams on reproduction activity. This variant offer a genetic gain per generation by 0.47497 additive standard deviations.

  5. Masculine sex ratios, population age structure and the potential spread of HIV in China

    OpenAIRE

    M. Giovanna Merli; Sara Hertog

    2010-01-01

    There is much speculation regarding the contribution of China's changing demography to the spread of HIV/AIDS. We employ a bio-behavioral macrosimulation model of the heterosexual spread of HIV/AIDS to evaluate the roles that China's unique demographic conditions -- (1) masculine sex ratios at birth and (2) a population age structure that reflects rapid fertility decline since the 1970's -- play in altering the market for sexual partners, thereby potentially fueling an increase...

  6. Where is the bride? Progressively declining sex ratio in India: an alarming signal for imbalanced society

    OpenAIRE

    Nirmala Sharma; Kana Ram; Anand Sharma; Shashi Sharma

    2014-01-01

    Female feticide is an extreme form of violence against women, the most active part is being played by the women themselves just for the mere want of a boy, mothers dont feel bad in strangulating their own daughters in their wombs. From decades of sex determination and female feticide is creating a statistical imbalance regarding the commonly expected and lsquo;male: female' birth ratio in India. This offense have been spreaded to the states in India like Punjab, Haryana, Delhi, Gujarat and R...

  7. Toward a simple, repeatable, non-destructive approach to measuring stable-isotope ratios of water within tree stems

    Science.gov (United States)

    Raulerson, S.; Volkmann, T.; Pangle, L. A.

    2017-12-01

    Traditional methodologies for measuring ratios of stable isotopes within the xylem water of trees involve destructive coring of the stem. A recent approach involves permanently installed probes within the stem, and an on-site assembly of pumps, switching valves, gas lines, and climate-controlled structure for field deployment of a laser spectrometer. The former method limits the possible temporal resolution of sampling, and sample size, while the latter may not be feasible for many research groups. We present results from initial laboratory efforts towards developing a non-destructive, temporally-resolved technique for measuring stable isotope ratios within the xylem flow of trees. Researchers have used direct liquid-vapor equilibration as a method to measure isotope ratios of the water in soil pores. Typically, this is done by placing soil samples in a fixed container, and allowing the liquid water within the soil to come into isotopic equilibrium with the headspace of the container. Water can also be removed via cryogenic distillation or azeotropic distillation, with the resulting liquid tested for isotope ratios. Alternatively, the isotope ratios of the water vapor can be directly measured using a laser-based water vapor isotope analyzer. Well-established fractionation factors and the isotope ratios in the vapor phase are then used to calculate the isotope ratios in the liquid phase. We propose a setup which would install a single, removable chamber onto a tree, where vapor samples could non-destructively and repeatedly be taken. These vapor samples will be injected into a laser-based isotope analyzer by a recirculating gas conveyance system. A major part of what is presented here is in the procedure of taking vapor samples at 100% relative humidity, appropriately diluting them with completely dry N2 calibration gas, and injecting them into the gas conveyance system without inducing fractionation in the process. This methodology will be helpful in making

  8. Inverse sex effects on performance of domestic dogs (Canis familiaris) in a repeated problem-solving task.

    Science.gov (United States)

    Duranton, Charlotte; Rödel, Heiko G; Bedossa, Thierry; Belkhir, Séverine

    2015-02-01

    The authors investigated differences between female and male pet dogs in physical cognition using an object manipulation task. Subjects (24 females and 23 males of different breeds) had to open a box in order to obtain a food reward during 3 consecutive trials, and latency times before success were measured. Males were significantly more successful in opening the box during the first trial. However, this sex difference was inversed when successful individuals were retested. During the following 2 trials, females were more successful than males, indicating that they were able to improve their skills more quickly once they had managed to succeed for a first time. Sex-specific dynamics in repeated problem-solving tasks might be an important contributor to individual differences in cognitive performance of pet dogs. PsycINFO Database Record (c) 2015 APA, all rights reserved.

  9. Enzymatic amplification of a Y chromosome repeat in a single blastomere allows identification of the sex of preimplantation mouse embryos

    International Nuclear Information System (INIS)

    Bradbury, M.W.; Isola, L.M.; Gordon, J.W.

    1990-01-01

    The polymerase chain reaction (PCR) technique has been adapted to identify the sex of preimplantation mouse embryos rapidly. PCR was used to amplify a specific repeated DNA sequence on the Y chromosome from a single isolated blastomere in under 12 hr. The remainder of the biopsied embryo was then transferred to a pseudopregnant female and carried to term. Using this technique, 72% of embryos can be classed as potentially either male or female. Transfers of such embryos have produced pregnancies with 8/8 fetuses (100%) being of the predicted sex. Variations of the technique have demonstrated certain limitations to the present procedure as well as indicated possible strategies for improvement of the assay. The PCR technique may have wide application in the genetic analysis of preimplantation embryos

  10. Effects of Repeated Concussions and Sex on Early Processing of Emotional Facial Expressions as Revealed by Electrophysiology.

    Science.gov (United States)

    Carrier-Toutant, Frédérike; Guay, Samuel; Beaulieu, Christelle; Léveillé, Édith; Turcotte-Giroux, Alexandre; Papineau, Samaël D; Brisson, Benoit; D'Hondt, Fabien; De Beaumont, Louis

    2018-05-06

    Concussions affect the processing of emotional stimuli. This study aimed to investigate how sex interacts with concussion effects on early event-related brain potentials (ERP) measures (P1, N1) of emotional facial expressions (EFE) processing in asymptomatic, multi-concussion athletes during an EFE identification task. Forty control athletes (20 females and 20 males) and 43 multi-concussed athletes (22 females and 21 males), recruited more than 3 months after their last concussion, were tested. Participants completed the Beck Depression Inventory II, the Beck Anxiety Inventory, the Post-Concussion Symptom Scale, and an Emotional Facial Expression Identification Task. Pictures of male and female faces expressing neutral, angry, and happy emotions were randomly presented and the emotion depicted had to be identified as fast as possible during EEG acquisition. Relative to controls, concussed athletes of both sex exhibited a significant suppression of P1 amplitude recorded from the dominant right hemisphere while performing the emotional face expression identification task. The present study also highlighted a sex-specific suppression of the N1 component amplitude after concussion which affected male athletes. These findings suggest that repeated concussions alter the typical pattern of right-hemisphere response dominance to EFE in early stages of EFE processing and that the neurophysiological mechanisms underlying the processing of emotional stimuli are distinctively affected across sex. (JINS, 2018, 24, 1-11).

  11. Colony size, sex ratio and cohabitation in roosts of Phyllostomus hastatus (Pallas (Chiroptera: Phyllostomidae

    Directory of Open Access Journals (Sweden)

    LM. Costa

    Full Text Available Phyllostomus hastatus bat is species broadly distributed over the Neotropical region, which uses as diurnal roosts caves, hollow trees, palm leaves and human buildings. Thirteen diurnal roosts of P. hastatus were analysed from 1990 to 2009 in several localities of Rio de Janeiro State, regarding environment (rural, urban or protected area, type of roost (hollow tree, basement or roof, sex ratio and cohabitation. A nocturnal roost was also analysed. Sex ratio of P. hastatus varied considerably among roosts what may be explained by the fact this species can roost alone, in couples, in harems or in groups of bachelor males. Phyllostomus hastatus was observed in cohabitation with three other species: Molossus rufus, Molossus molossus and Myotis nigricans. Due to the frequency of cohabitation observed between P. hastatus and species of the genus Molossus, one or more advantages for the members of this association may be expected. The simultaneous usage of a feeding roost by a group of bachelor males is unknown information in the literature, and may suggest that this kind of group may interact with each other even when away from their diurnal roosts.

  12. High fat diet prevents over-crowding induced decrease of sex ratio in mice.

    Directory of Open Access Journals (Sweden)

    Madhukar Shivajirao Dama

    Full Text Available Adaptive theory predicts that mothers would be advantaged by adjusting the sex ratio of their offspring in relation to their offspring's future reproductive success. In the present study, we tested the effect of housing mice under crowded condition on the sex ratio and whether the fat content of the diet has any influence on the outcome of pregnancies. Three-week-old mice were placed on the control diet (NFD for 3 weeks. Thereafter the mice were allotted randomly to two groups of 7 cages each with 4, 6, 8, 10, 12, 14, and 16 mice in every cage to create increasing crowding gradient and fed either NFD or high fat diet (HFD. After 4 weeks, dams were bred and outcomes of pregnancy were analyzed. The average dam body weight (DBW at conception, litter size (LS and SR were significantly higher in HFD fed dams. Further, male biased litters declined with increasing crowding in NFD group but not in HFD. The LS and SR in NFD declined significantly with increasing crowding, whereas only LS was reduced in HFD group. We conclude that female mice housed under overcrowding conditions shift offspring SR in favor of daughters in consistent with the TW hypothesis and high fat diet reduces this influence of overcrowding.

  13. Resource Elasticity of Offspring Survival and the Optimal Evolution of Sex Ratios

    Science.gov (United States)

    Wang, Rui-Wu; Wang, Ya-Qiang; He, Jun-Zhou; Li, Yao-Tang

    2013-01-01

    The fitness of any organisms includes the survival and reproductive rate of adults and the survival of their offspring. Environmental selection pressures might not affect these two aspects of an organism equally. Assuming that an organism first allocates its limited resources to maintain its survival under environmental selection pressure, our model, based on the evolutionarily stable strategy theory, surprisingly shows that the sex ratio is greatly affected by the environmental pressure intensity and by the reproductive resource elasticity of offspring survival. Moreover, the concept of the resource elasticity of offspring survival intrinsically integrates the ecological concepts of K selection and r selection. The model shows that in a species with reproductive strategy K, increased environmental selection pressure will reduce resource allocation to the male function. By contrast, in a species with reproductive strategy r, harsher environmental selection pressure will increase allocation to the male function. The elasticity of offspring survival might vary not only across species, but also across many other factors affecting the same species (e.g., age structure, spatial heterogeneity), which explains sex ratio differences across species or age structures and spatial heterogeneity in the same species. PMID:23468826

  14. Birth order and sibling sex ratio of children and adolescents referred to a gender identity service.

    Directory of Open Access Journals (Sweden)

    Doug P Vanderlaan

    Full Text Available In adult male samples, homosexuality is associated with a preponderance of older brothers (i.e., the fraternal birth order effect. In several studies comparing gender dysphoric youth, who are likely to be homosexual in adulthood, to clinical or non-clinical control groups, the findings have been consistent with the fraternal birth order effect in males; however, less is known about unique sibship characteristics of gender dysphoric females. The current study investigated birth order and sibling sex ratio in a large sample of children and adolescents referred to the same Gender Identity Service (N = 768. Probands were classified as heterosexual males, homosexual males, or homosexual females based on clinical diagnostic information. Groups differed significantly in age and sibship size, and homosexual females were significantly more likely to be only children. Subsequent analyses controlled for age and for sibship size. Compared to heterosexual males, homosexual males had a significant preponderance of older brothers and homosexual females had a significant preponderance of older sisters. Similarly, the older sibling sex ratio of homosexual males showed a significant excess of brothers whereas that of homosexual females showed a significant excess of sisters. Like previous studies of gender dysphoric youth and adults, these findings were consistent with the fraternal birth order effect. In addition, the greater frequency of only children and elevated numbers of older sisters among the homosexual female group adds to a small literature on sibship characteristics of potential relevance to the development of gender identity and sexual orientation in females.

  15. Birth order and sibling sex ratio of children and adolescents referred to a gender identity service.

    Science.gov (United States)

    Vanderlaan, Doug P; Blanchard, Ray; Wood, Hayley; Zucker, Kenneth J

    2014-01-01

    In adult male samples, homosexuality is associated with a preponderance of older brothers (i.e., the fraternal birth order effect). In several studies comparing gender dysphoric youth, who are likely to be homosexual in adulthood, to clinical or non-clinical control groups, the findings have been consistent with the fraternal birth order effect in males; however, less is known about unique sibship characteristics of gender dysphoric females. The current study investigated birth order and sibling sex ratio in a large sample of children and adolescents referred to the same Gender Identity Service (N = 768). Probands were classified as heterosexual males, homosexual males, or homosexual females based on clinical diagnostic information. Groups differed significantly in age and sibship size, and homosexual females were significantly more likely to be only children. Subsequent analyses controlled for age and for sibship size. Compared to heterosexual males, homosexual males had a significant preponderance of older brothers and homosexual females had a significant preponderance of older sisters. Similarly, the older sibling sex ratio of homosexual males showed a significant excess of brothers whereas that of homosexual females showed a significant excess of sisters. Like previous studies of gender dysphoric youth and adults, these findings were consistent with the fraternal birth order effect. In addition, the greater frequency of only children and elevated numbers of older sisters among the homosexual female group adds to a small literature on sibship characteristics of potential relevance to the development of gender identity and sexual orientation in females.

  16. Offspring sex ratios in relation to mutual ornamentation and extra-pair paternity in the Black Swan Cygnus atratus

    NARCIS (Netherlands)

    Kraaijeveld, Ken; Ming, Ma; Komdeur, Jan; Mulder, Raoul A.

    In sexually dichromatic birds, females may adaptively adjust the sex ratio of their offspring prior to hatching in relation to male ornamentation, for example, by producing more sons when paired to a highly attractive partner. However, to our knowledge no studies have investigated offspring sex

  17. The Sex Ratio of Full and Half Siblings of People Diagnosed With ADHD in Childhood and Adolescence

    DEFF Research Database (Denmark)

    Mouridsen, Svend Erik Birkebæk; Rich, Bente; Isager, Torben

    2014-01-01

    Objective:It has been suggested that high levels of prenatal testosterone exposure are implied in the etiology of male preponderance disorders such as autism spectrum disorder and ADHD. Within this scope, we studied the sex ratio (proportion of males) in siblings of individuals diagnosed with ADHD...... in childhood and adolescence. Method: We did a nationwide, register-based cohort study of the sex ratio in siblings of the 16,381 patients in Denmark diagnosed with ADHD at age 17 years and younger and registered in the nationwide Danish Psychiatric Central Register between January 1, 1994 and May 28, 2013....... Results: Among the 33,151 siblings, 17,041 were males and 16,110 females. This yields a sex ratio of 0.514, which is not statistically significant different from the Danish live birth sex ratio of 0.513 during the relevant years (p = .70). Conclusion: These findings provide no support for the hypothesis...

  18. Age- and Sex-Dependent Impact of Repeated Social Stress on Intrinsic and Synaptic Excitability of the Rat Prefrontal Cortex.

    Science.gov (United States)

    Urban, Kimberly R; Valentino, Rita J

    2017-01-01

    Stress is implicated in psychiatric illnesses that are characterized by impairments in cognitive functions that are mediated by the medial prefrontal cortex (mPFC). Because sex and age determine stress vulnerability, the effects of repeated social stress occurring during early adolescence, mid-adolescence, or adulthood on the cellular properties of male and female rat mPFC Layer V neurons in vitro were examined. Repeated resident-intruder stress produced age- and sex-specific effects on mPFC intrinsic and synaptic excitability. Mid-adolescents were particularly vulnerable to effects on intrinsic excitability. The maximum number of action potentials (APs) evoked by increasing current intensity was robustly decreased in stressed male and female mid-adolescent rats compared with age-matched controls. These effects were associated with stress-induced changes in AP half-width, amplitude, threshold, and input resistance. Social stress at all ages generally decreased synaptic excitability by decreasing the amplitude of spontaneous excitatory postsynaptic potentials. The results suggest that whereas social stress throughout life can diminish the influence of afferents driving the mPFC, social stress during mid-adolescence additionally affects intrinsic characteristics of mPFC neurons that determine excitability. The depressant effects of social stress on intrinsic and synaptic mPFC neurons may underlie its ability to affect executive functions and emotional responses, particularly during adolescence. © The Author 2016. Published by Oxford University Press.

  19. The Effects of Sex-Ratio and Density on Locomotor Activity in the House Fly, Musca domestica

    OpenAIRE

    Bahrndorff, Simon; Kjærsgaard, Anders; Pertoldi, Cino; Loeschcke, Volker; Schou, Toke M.; Skovgård, Henrik; Hald, Birthe

    2012-01-01

    Although locomotor activity is involved in almost all behavioral traits, there is a lack of knowledge on what factors affect it. This study examined the effects of sex-ratio and density on the circadian rhythm of locomotor activity of adult Musca domestica L. (Diptera: Muscidae) using an infra-red light system. Sex-ratio significantly affected locomotor activity, increasing with the percentage of males in the vials. In accordance with other studies, males were more active than females, but th...

  20. A framework for analyzing sex-selective abortion: the example of changing sex ratios in Southern Caucasus

    Science.gov (United States)

    Hohmann, Sophie A; Lefèvre, Cécile A; Garenne, Michel L

    2014-01-01

    The paper proposes a socioeconomic framework of supply, demand, and regulation to explain the development of sex-selective abortion in several parts of the world. The framework is then applied to three countries of southern Caucasus (Armenia, Azerbaijan, and Georgia) where sex-selective abortion has developed since the collapse of the Soviet Union. The authors argue that sex-selective abortion cannot be explained simply by patriarchal social systems, sex discrimination, or son preference. The emphasis is put on the long-term acceptability of abortion in the region, on acceptability of sex-screening by both the medical establishment and by the population, on newly imported techniques of sex-screening, and on the changing demand for children associated with the major economic and social changes that followed the dismantlement of the Soviet Union. PMID:25349481

  1. Pregravid hypertension may have different secondary sex ratio effects in different races in the United States.

    Science.gov (United States)

    Grech, Victor

    2017-12-01

    Males are born in excess of females and the ratio is expressed as M/F (male/female births=secondary sex ratio, also known as secondary sex ratio). This is expected to approximate 1.048. Racial M/F disparities are known. A recent study in China showed that pregravid systolic hypertension is higher in women who delivered a boy than in those who had a girl. This study was carried out in order to identify the effect of pregravid hypertension in the United States on M/F by race. Monthly male and female live births by race for the entire US along with the presence/absence of hypertension were obtained from the website of the Centers for Disease Control and Prevention for 2007-2015 for the four racial groups: American Indian or Alaska Native, Asian or Pacific Islander, Black or African American and White. This study analysed 36,364,253 live births. For White births, mothers who had chronic hypertension were likelier to have male than female offspring when compared to non-hypertensives (p=0.003). Conversely, Black or African American mothers who had hypertension were less likely to have male than female offspring when compared to non-hypertensives (p=0.022). There were F differences for/F differences for the presence or absence of hypertension for the other two races or for the total. It is possible that hypothesised innate interracial periconceptual hormonal differences may modulate M/F responses to hypertension in different races. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Effect of Temperature on Reproduction and Sex Ratio of Guppy (Poecilia reticulata Peters

    Directory of Open Access Journals (Sweden)

    H. Arfah

    2007-01-01

    Full Text Available Water temperature could affect the reproduction of broodstock and sex ratio of progeny.  In this study, broodstock of guppy (Poecilia reticulata Peters was reared in different temperature to determine its effect on reproduction of broodstock and sex ratio of their progeny. The result of study show that broodstock reared at 27°C produced more fry (16 males mean than that of 30°C (10 males, while broodstock reared at 33°C produced no progeny.  Percentage of male fish produced by broodstock reared at 30°C is higher than that of 27°C.  Incubation time of embryo before birth is sorter in broodstock reared at 30°C (4-12 days compared with 27°C (18-22 days.  However, several progeny of broodstock reared at 30°C had abnormal vertebrae. Keywords: guppy, Poecilia reticulata, sex reversal, reproduction, monosex   ABSTRAK Suhu air inkubasi diduga dapat mempengaruhi reproduksi induk ikan dan nisbah kelamin keturunannya.  Pada penelitian ini, induk ikan gapi (Poecilia reticulata Peters dipelihara pada suhu 27°C, 30°C dan suhu 33°C untuk mengetahui pengaruhnya terhadap reproduksi dan rasio kelamin keturunannya.  Hasil penelitian menunjukkan bahwa induk ikan gapi yang dipelihara pada suhu 27°C menghasilkan anak lebih banyak (rata-rata 16 ekor daripada di suhu 30°C (10 ekor, sementara induk gagal melahirkan pada suhu pemeliharaan 33°C. Proporsi anak jantan yang dihasilkan oleh induk yang dipelihara pada suhu 30°C lebih banyak dibandingkan pada suhu 27°C.  Waktu inkubasi embrio sebelum dilahirkan oleh induk yang dipelihara pada suhu 30°C lebih singkat, yaitu 4-12 hari, dibandingkan pada  suhu 27°C, 18-22 hari.  Namun demikian beberapa anak ikan yang lahir dari induk yang dipelihara pada suhu suhu 30°C mengalami abnormalitas pada bagian tulang belakangnya.  Kata kunci: ikan gapi, Poecilia reticulata, sex reversal, reproduksi, monoseks

  3. Postzygotic incompatibilities between the pupfishes, Cyprinodon elegans and Cyprinodon variegatus: hybrid male sterility and sex ratio bias.

    Science.gov (United States)

    Tech, C

    2006-11-01

    I examined the intrinsic postzygotic incompatibilities between two pupfishes, Cyprinodon elegans and Cyprinodon variegatus. Laboratory hybridization experiments revealed evidence of strong postzygotic isolation. Male hybrids have very low fertility, and the survival of backcrosses into C. elegans was substantially reduced. In addition, several crosses produced female-biased sex ratios. Crosses involving C. elegans females and C. variegatus males produced only females, and in backcrosses involving hybrid females and C. elegans males, males made up approximately 25% of the offspring. All other crosses produced approximately 50% males. These sex ratios could be explained by genetic incompatibilities that occur, at least in part, on sex chromosomes. Thus, these results provide strong albeit indirect evidence that pupfish have XY chromosomal sex determination. The results of this study provide insight on the evolution of reproductive isolating mechanisms, particularly the role of Haldane's rule and the 'faster-male' theory in taxa lacking well-differentiated sex chromosomes.

  4. Reproductive seasonality, sex ratio and philopatry in Argentina's common vampire bats

    Science.gov (United States)

    Delpietro, H. A.; Russo, R. G.; Lord, R. D.; Delpietro, G. L.

    2017-01-01

    Common vampire bats (Desmodus rotundus) are a key rabies vector in South America. Improved management of this species requires long-term, region-specific information. To investigate patterns of demography and dispersal, we analysed 13 642 captures of common vampire bats in Northern Argentina from the period 1969–2004. In contrast with findings from more tropical regions, we found reproductive seasonality with peak pregnancy in September and peak lactation in February. Curiously, sex ratios were consistently male-biased both in maternity roosts and at foraging sites. Males comprised 57% of 9509 adults caught at night, 57% of 1078 juveniles caught at night, 57% of 603 juveniles caught in roosts during the day, and 55% of 103 newborns and mature fetuses. Most observed roosts were in man-made structures. Movements of 1.5–54 km were most frequent in adult males, followed by young males, adult females and young females. At night, males visited maternity roosts, and non-pregnant, non-lactating females visited bachelor roosts. Males fed earlier in the night. Finally, we report new longevity records for free-ranging vampire bats: 16 and 17 years of age for a female and male, respectively. Our results are consistent with model predictions that sex-biased movements might play a key role in rabies transmission between vampire bat populations. PMID:28484615

  5. Reproductive seasonality, sex ratio and philopatry in Argentina's common vampire bats.

    Science.gov (United States)

    Delpietro, H A; Russo, R G; Carter, G G; Lord, R D; Delpietro, G L

    2017-04-01

    Common vampire bats ( Desmodus rotundus ) are a key rabies vector in South America. Improved management of this species requires long-term, region-specific information. To investigate patterns of demography and dispersal, we analysed 13 642 captures of common vampire bats in Northern Argentina from the period 1969-2004. In contrast with findings from more tropical regions, we found reproductive seasonality with peak pregnancy in September and peak lactation in February. Curiously, sex ratios were consistently male-biased both in maternity roosts and at foraging sites. Males comprised 57% of 9509 adults caught at night, 57% of 1078 juveniles caught at night, 57% of 603 juveniles caught in roosts during the day, and 55% of 103 newborns and mature fetuses. Most observed roosts were in man-made structures. Movements of 1.5-54 km were most frequent in adult males, followed by young males, adult females and young females. At night, males visited maternity roosts, and non-pregnant, non-lactating females visited bachelor roosts. Males fed earlier in the night. Finally, we report new longevity records for free-ranging vampire bats: 16 and 17 years of age for a female and male, respectively. Our results are consistent with model predictions that sex-biased movements might play a key role in rabies transmission between vampire bat populations.

  6. Education and gender bias in the sex ratio at birth: evidence from India.

    Science.gov (United States)

    Echávarri, Rebeca A; Ezcurra, Roberto

    2010-02-01

    This article investigates the possible existence of a nonlinear link between female disadvantage in natality and education. To this end, we devise a theoretical model based on the key role of social interaction in explaining people's acquisition of preferences, which justifies the existence of a nonmonotonic relationship between female disadvantage in natality and education. The empirical validity of the proposed model is examined for the case of India, using district-level data. In this context, our econometric analysis pays particular attention to the role of spatial dependence to avoid any potential problems of misspecification. The results confirm that the relationship between the sex ratio at birth and education in India follows an inverted U-shape. This finding is robust to the inclusion of additional explanatory variables in the analysis, and to the choice of the spatial weight matrix used to quantify the spatial interdependence between the sample districts.

  7. Population and colony-level determinants of tertiary sex ratio in the declining barn swallow.

    Directory of Open Access Journals (Sweden)

    Nicola Saino

    Full Text Available Sex ratio of adults (tertiary sex ratio, TSR is a major feature of animal populations with consequences for their behaviour, genetic structure and viability. Spatial and temporal variation in TSR occurs within species but the mechanisms behind it are poorly understood. In this long-term study of a declining population of a socially monogamous, colonial, migratory bird, the barn swallow (Hirundo rustica, we first analyzed population-level variation in TSR ( =  proportion of males of yearlings at sexual maturation in relation to ecological conditions as gauged by annual survival rate of adults. TSR was male-biased both among yearlings and older individuals, but male bias of yearlings was more pronounced after years with larger decline in adult survival. Thus, male offspring were less susceptible to the adverse ecological conditions that cause increased mortality. Dispersal and settling site decisions can have major consequences on fitness via the effects of local TSR on mating and sperm competition. Breeding barn swallows are highly philopatric while natal dispersal is high and, together with mortality, is the main determinant of colony TSR. We thus also investigated the mechanisms of breeding colony choice by yearlings and found that TSR of new-settlers in a given colony and year was negatively predicted by TSR of returning, early arriving older individuals in that year, but not by overall TSR at the colony in the previous year. This suggests that in our male-biased population new-settler males respond to local TSR upon arrival to choose the sites with larger breeding opportunities. Hence, variation in ecological conditions as reflected by adult survival can shift the TSR of individuals recruiting into a local population, with potentially various demographic consequences. However, breeding site choice based on TSR tends to homogenize TSR at a population level likely by facilitating settling of dispersing males in colonies with less male

  8. Parental behaviour is unrelated to experimentally manipulated great tit brood sex ratio

    NARCIS (Netherlands)

    Lessells, C.M.; Oddie, K.R.; Mateman, A.C.

    1998-01-01

    Parental investment may be biased with respect to parental sex or offspring sex or there may be an interaction between parental and offspring sex. We investigated whether any of these types of bias occurred in great tits, Parus major. By sexing chicks using random amplified polymorphic DNA (RAPD)

  9. EFFECTS OF STRESSFUL EVENTS IN FRANCE (1968) AND JAPAN (1995) ON THE SEX RATIO AT BIRTH.

    Science.gov (United States)

    Grech, Victor; Zammit, Dorota; Scherb, Hagen

    2017-09-01

    Males are usually born in excess of females. The sex ratio at birth (SR) is often expressed as the ratio of male to total births. A wide variety of factors have been shown to influence SR, including terrorist attacks, which have been shown to reduce SR. This paper reviews the effects on SR outcomes of the stressful events in France in 1968 (in association with the student and worker riots) and in Japan following the Aum Shinrikyo religious cult's attack on the Tokyo subway using sarin nerve gas in 1995. Both countries displayed seasonal variation in SR. France exhibited a decline in SR in 1968 (p=0.042), with a particularly strong dip in May of that year (p=0.015). For Japan, there was no statistically significant dip for 1995 but there was a significant dip in June of that year (p=0.026). The SR dips follow catastrophic or tragic events if these are perceived to be momentous enough by a given populace. It is believed that SR slumps may be caused by population stress, which is known to lead to the culling of frail/small male fetuses. It has been observed that these fluctuations are comparable in intensity to a substantial proportion of quoted values for perinatal mortality, potentially making this a public health issue.

  10. Changing approaches of prosecutors towards juvenile repeated sex-offenders: A Bayesian evaluation.

    Science.gov (United States)

    Bandyopadhyay, Dipankar; Sinha, Debajyoti; Lipsitz, Stuart; Letourneau, Elizabeth

    2010-06-01

    Existing state-wide data bases on prosecutors' decisions about juvenile offenders are important, yet often un-explored resources for understanding changes in patterns of judicial decisions over time. We investigate the extent and nature of change in judicial behavior towards juveniles following the enactment of a new set of mandatory registration policies between 1992 and 1996 via analyzing the data on prosecutors' decisions of moving forward for youths repeatedly charged with sexual violence in South Carolina. We use a novel extension of random effects logistic regression model for longitudinal binary data via incorporating an unknown change-point year. For convenient physical interpretation, our models allow the proportional odds interpretation of effects of the explanatory variables and the change-point year with and without conditioning on the youth-specific random effects. As a consequence, the effects of the unknown change-point year and other factors can be interpreted as changes in both within youth and population averaged odds of moving forward. Using a Bayesian paradigm, we consider various prior opinions about the unknown year of the change in the pattern of prosecutors' decision. Based on the available data, we make posteriori conclusions about whether a change-point has occurred between 1992 and 1996 (inclusive), evaluate the degree of confidence about the year of change-point, estimate the magnitude of the effects of the change-point and other factors, and investigate other provocative questions about patterns of prosecutors' decisions over time.

  11. Phenotypic plasticity in response to the social environment: effects of density and sex ratio on mating behaviour following ecotype divergence.

    Directory of Open Access Journals (Sweden)

    Kristina Karlsson

    Full Text Available The ability to express phenotypically plastic responses to environmental cues might be adaptive in changing environments. We studied phenotypic plasticity in mating behaviour as a response to population density and adult sex ratio in a freshwater isopod (Asellus aquaticus. A. aquaticus has recently diverged into two distinct ecotypes, inhabiting different lake habitats (reed Phragmites australis and stonewort Chara tomentosa, respectively. In field surveys, we found that these habitats differ markedly in isopod population densities and adult sex ratios. These spatially and temporally demographic differences are likely to affect mating behaviour. We performed behavioural experiments using animals from both the ancestral ecotype ("reed" isopods and from the novel ecotype ("stonewort" isopods population. We found that neither ecotype adjusted their behaviour in response to population density. However, the reed ecotype had a higher intrinsic mating propensity across densities. In contrast to the effects of density, we found ecotype differences in plasticity in response to sex ratio. The stonewort ecotype show pronounced phenotypic plasticity in mating propensity to adult sex ratio, whereas the reed ecotype showed a more canalised behaviour with respect to this demographic factor. We suggest that the lower overall mating propensity and the phenotypic plasticity in response to sex ratio have evolved in the novel stonewort ecotype following invasion of the novel habitat. Plasticity in mating behaviour may in turn have effects on the direction and intensity of sexual selection in the stonewort habitat, which may fuel further ecotype divergence.

  12. Sex and repeated restraint stress interact to affect cat odor-induced defensive behavior in adult rats.

    Science.gov (United States)

    Perrot-Sinal, Tara S; Gregus, Andrea; Boudreau, Daniel; Kalynchuk, Lisa E

    2004-11-19

    The overall objective of the present experiment was to assess sex differences in the effects of repeated restraint stress on fear-induced defensive behavior and general emotional behavior. Groups of male and female Long-Evans rats received either daily restraint stress (stressed) or daily brief handling (nonstressed) for 21 consecutive days. On days 22-25, a number of behavioral tests were administered concluding with a test of defensive behavior in response to a predatory odor. Stressed and nonstressed males and females were exposed to a piece of cat collar previously worn by a female domestic cat (cat odor) or a piece of collar never worn by a cat (control odor) in a familiar open field containing a hide barrier. Rats displayed pronounced defensive behavior (increased hiding and risk assessment) and decreased nondefensive behavior (grooming, rearing) in response to the cat odor. Nonstressed females exposed to cat odor displayed less risk assessment behavior relative to nonstressed males exposed to cat odor. Restraint stress had little effect on defensive behavior in male rats but significantly increased risk assessment behaviors in females. Behavior on the Porsolt forced swim test (a measure of depression-like behavior) and the open field test (a measure of anxiety-like behavior) was not affected by stress or sex. These findings indicate the utility of the predator odor paradigm in detecting subtle shifts in naturally occurring anxiety-like behaviors that may occur differentially in males and females.

  13. Genes and chromosome arrangements affecting sex ratio in the Mediterranean fruit fly, Ceratitis capitata (Wied.)

    International Nuclear Information System (INIS)

    Wood, R.J.; Kafu, A.A.; Rendon Arana, P.A.; Owusu-Daaku, K.; Alcock, R.M.; Hallows, J.A.; Busch-Petersen, E.; Mani, G.S.

    1997-01-01

    The MP (male producing) factor, which shows temperature sensitive meiotic drive favoring the Y chromosome, proved to be highly variable in spermatozoal deficiency in different cysts within a single testis. However, the overall loss of sperm corresponded almost precisely with the loss of females. The minimum proportion of females consistently obtained in inbred lines was about 30-35%. On the basis of parallel studies with the mosquito Aedes aegypti, variability between cysts is open to interpretation in terms of different rates of senescence. The T:Y(wp + )30C genetic sexing strain, which is designed to generate males with brown (wild type) puparia and females with white puparia, was contaminated artificially in a series of population experiments to investigate the pattern of breakdown. Wild type contamination with either sex caused an increase of brown pupae. The sex ratio became progressively distorted in favour of females after contamination with females, mated or unmated, but not after male contamination. The experiments revealed evidence of a low frequency of natural recombination between wp + and the translocation breakpoint on the Y chromosome, shown by the appearance of wp males. The frequency of male recombination (r) and the selection coefficient (s) against wp/wp were measured over 11 generations. The best fit to the observed data was obtained with r = (0.14 ± 0.04)% and s=(26.0 ± 2.7)%. Using these estimates to predict the frequency of wp + females and wp males for up to 100 generations, it was concluded that white males would never exceed 0.5% whereas the frequency of brown females was expected to exceed 33% after 25 generations. Published data on the mass reared strain, maintained with a population size of 240,000 adult flies, were subjected to the same analysis. A higher value of s between (38.0 ± 3.2)% and (52.0 ± 0.3)% was obtained under these conditions. Electrophoretic studies on esterases revealed a significantly higher activity in a recently

  14. Mapping Causes and Implications of India's Skewed Sex Ratio and Poverty problem using Fuzzy & Neutrosophic Relational Maps

    OpenAIRE

    Gaurav; Kumar, Megha; Bhutani, Kanika; Aggarwal, Swati

    2016-01-01

    Numerous studies by different researchers have confirmed that skewed sex ratio is a critical social problem in India. This enduring problem of gender imbalance is the collective result of factors like sex selective abortion, gender discrimination, son preference for the preservation of tribe, emergence of new technologies in medical field and many more factors. Another severe problem to be addressed in India is poverty. Many factors contribute to the perpetuation of poverty such as illiteracy...

  15. Effects of gamma radiation on development, sterility, fecundity, and sex ratio of Dermanyssus gallinae (DeGeer) (Acari: Dermanyssidae)

    International Nuclear Information System (INIS)

    Entrekin, D.L.; Oliver, J.H. Jr.; Pound, J.M.

    1987-01-01

    Protonymphal Dermanyssus gallinae were irradiated with 0.50, 0.75, 1.0, 3.0, and 6.0 krad of gamma radiation and subsequently monitored regarding their developmental, feeding, and mating success. Also, sex ratios of adults treated as protonymphs were recorded as were sex ratios of embryos and F1 adults produced by these adults. Doses up to 1.0 krad did not prevent development of treated protonymphs to the adult stage or stop mating. Three krad reduced the number of treated protonymphs attaining adulthood and 6.0-krad treatment prevented all mites from developing to the adult stage. Egg (embryo) production was normal for mites treated with 0.50 krad, but significantly curtailed by doses of 0.75 krad and greater. Radiation doses used in this study did not appear to affect the normal variable sex ratios observed in untreated mites

  16. Does the sex ratio at sexual maturity affect men's later-life mortality risks? Evidence from historical China.

    Science.gov (United States)

    Zang, Emma; Zheng, Hui

    2018-04-01

    This study examines the relationship between the male-to-female sex ratio (measured as the proportion male) at sexual maturity and later-life mortality risks in the context of pre-industrial northeast China, using registration data from the Qing Dynasty. We find that a higher male-to-female sex ratio at sexual maturity is associated with a higher later-life mortality risk among men. This association is likely due to the long-term adverse consequences of stress caused by low mate availability at sexual maturity. We further find that a high sex ratio at sexual maturity mitigates the health benefits of marriage and exacerbates the health disadvantages of holding an official position in Qing China. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Auger electron spectroscopy for the determination of sex and age related Ca/P ratio at different bone sites

    International Nuclear Information System (INIS)

    Balatsoukas, Ioannis; Kourkoumelis, Nikolaos; Tzaphlidou, Margaret

    2010-01-01

    The Ca/P ratio of normal cortical and trabecular rat bone was measured by Auger electron spectroscopy (AES). Semiquantitative analysis was carried out using ratio techniques to draw conclusions on how age, sex and bone site affect the relative composition of calcium and phosphorus. Results show that Ca/P ratio is not sex dependent; quite the opposite, bone sites exhibit variations in elemental stoichiometry where femoral sections demonstrate higher Ca/P ratio than rear and front tibias. Age-related changes are more distinct for cortical bone in comparison with the trabecular bone. The latter's Ca/P ratio remains unaffected from all the parameters under study. This study confirms that AES is able to successfully quantify bone mineral main elements when certain critical points, related to the experimental conditions, are addressed effectively.

  18. Do brood sex ratio, nestling development and sex affect fledging timing and order? An experimental study on great tits

    NARCIS (Netherlands)

    Radersma, Reinder; Tinbergen, Joost M.; Komdeur, Jan

    The process of nest leaving (fledging) in hole-breeding passerines is largely unexplored, although it is potentially an important facet of reproduction. We used the great tit, Parus major, to investigate whether fledging timing and order were affected by nestling development and sex, as well as the

  19. Sex-specific effects of altered competition on nestling growth and survival: an experimental manipulation of brood size and sex ratio.

    Science.gov (United States)

    Nicolaus, Marion; Michler, Stephanie P M; Ubels, Richard; van der Velde, Marco; Komdeur, Jan; Both, Christiaan; Tinbergen, Joost M

    2009-03-01

    1. An increase of competition among adults or nestlings usually negatively affects breeding output. Yet little is known about the differential effects that competition has on the offspring sexes. This could be important because it may influence parental reproductive decisions. 2. In sexual size dimorphic species, two main contradictory mechanisms are proposed regarding sex-specific effects of competition on nestling performance assuming that parents do not feed their chicks differentially: (i) the larger sex requires more resources to grow and is more sensitive to a deterioration of the rearing conditions ('costly sex hypothesis'); (ii) the larger sex has a competitive advantage in intra-brood competition and performs better under adverse conditions ('competitive advantage hypothesis'). 3. In the present study, we manipulated the level of sex-specific sibling competition in a great tit population (Parus major) by altering simultaneously the brood size and the brood sex ratio on two levels: the nest (competition for food among nestlings) and the woodlot where the parents breed (competition for food among adults). We investigated whether altered competition during the nestling phase affected nestling growth traits and survival in the nest and whether the effects differed between males, the larger sex, and females. 4. We found a strong negative and sex-specific effect of experimental brood size on all the nestling traits. In enlarged broods, sexual size dimorphism was smaller which may have resulted from biased mortality towards the less competitive individuals i.e. females of low condition. No effect of brood sex ratio on nestling growth traits was found. 5. Negative brood size effects on nestling traits were stronger in natural high-density areas but we could not confirm this experimentally. 6. Our results did not support the 'costly sex hypothesis' because males did not suffer from higher mortality under harsh conditions. The 'competitive advantage hypothesis' was

  20. Changes in Income at Macro Level Predict Sex Ratio at Birth in OECD Countries.

    Science.gov (United States)

    Kanninen, Ohto; Karhula, Aleksi

    2016-01-01

    The human sex ratio at birth (SRB) is approximately 107 boys for every 100 girls. SRB was rising until the World War II and has been declining slightly after the 1950s in several industrial countries. Recent studies have shown that SRB varies according to exposure to disasters and socioeconomic conditions. However, it remains unknown whether changes in SRB can be explained by observable macro-level socioeconomic variables across multiple years and countries. Here we show that changes in disposable income at the macro level positively predict SRB in OECD countries. A one standard deviation increase in the change of disposable income is associated with an increase of 1.03 male births per 1000 female births. The relationship is possibly nonlinear and driven by extreme changes. The association varies from country to country being particular strong in Estonia. This is the first evidence to show that economic and social conditions are connected to SRB across countries at the macro level. This calls for further research on the effects of societal conditions on general characteristics at birth.

  1. Flight patterns and sex ratio of beetles of the subfamily Dynastinae (Coleoptera, Melolonthidae

    Directory of Open Access Journals (Sweden)

    Larissa Simões Corrêa de Albuquerque

    2016-09-01

    Full Text Available ABSTRACT Dynastinae is one of the most representative subfamilies of Melolonthidae (Scarabaeoidea and has considerable ecological importance due mainly to interactions with plants of the families Araceae and Annonaceae. This relationship has led to the evolution of nocturnal activity patterns, which are influenced by environmental conditions. In the present study, abiotic factors were investigated to comprehend the influence on the flight patterns and identify the sex ratio of beetles from this subfamily. A study was conducted at Campo de Instrução Marechal Newton Cavalcanti in northeastern Brazil between December 2010 and November 2011. Thirteen species of Dynastinae were identified, most of which were from the genus Cyclocephala. Abundance and richness were greater in the dry season. Six species exhibited peak flight activity at specific periods of the night. More females than males were recorded for Cyclocephala distincta and C. paraguayensis. The present findings suggest that rainfall reduces the flight activity of these beetles and different time schedules may be related to mating behavior, foraging behavior and the avoidance of interspecific resource competition.

  2. Outline on populations of Nagasaki A-bomb survivors and sex ratio in their children

    International Nuclear Information System (INIS)

    Yoshikawa, Isao; Inoue, Akira; Shiomi, Toshio

    1978-01-01

    On the basis of file delivered together with A-bomb surrivor's health Cards in Nagasaki, statistical management was performed on a mass of A-bomb survivors. The number of A-bomb survivors in a mass was 97,032. A family investigation by census registration was performed on 2,547 of A-bomb survivor group (the distance from the center of explosion recorded on cards was within 1.5 km) and 2,791 of its control group. As to 2,547 of A-bomb survivor group, each exposure place was determined, the distance from the center of explosion was measured again, and exposure dose was presumed. The mean exposure dose of A-bomb survivor group was 577 rad in male, and 681 rad in female. By adding A-bomb survivor group to the control group, 4,452 pairs of marriage were confirmed by census registration, and the number of their children was 10,073. With respect to changes of sex ratio, in case of exposed mother, it was expected theoretically that the number of male would decrease together with an decrease of dose, but an opposite change was recognized in a result of the investigation. A result in case of exposed father showed an increase of the male number although not significantly and a change towards the expected direction. (Tsunoda, M.)

  3. Further observations on sex ratio among infants born to survivors of the atomic bombs, Hiroshima and Nagasaki

    Energy Technology Data Exchange (ETDEWEB)

    Schull, W J; Neel, J V; Hashizume, Asaji

    1965-11-18

    Data are presented on the sex ratio of 47,624 children born in Hiroshima and Nagasaki during 1956 to 1962. The total number of births in these two cities for which information is available is now 140,542, and of this number in 73,994 instances one or both parents were exposed to the atomic bombs. The suggestion of an effect of exposure on sex ratio in the earlier data is not borne out by the present findings. One can argue either that a small early effect has disappeared or that the original observation had no biological significance. 27 references, 4 tables.

  4. Cognitive ability correlates positively with son birth and predicts cross-cultural variation of the offspring sex ratio

    Science.gov (United States)

    Dama, Madhukar Shivajirao

    2013-06-01

    Human populations show remarkable variation in the sex ratio at birth which is believed to be related to the parental condition. In the present study, the global variation of sex ratio at birth (SRB, proportion of male offspring born) was analyzed with respect to indirect measure of condition, the intelligence quotient (IQ). IQ correlates strongly with lifespan across nations, which makes it a good indicator of health of the large populations. Relation between three standard measures of average national IQ and SRB was studied using multiple linear regression models. Average national IQ was positively correlated with SRB ( r = 0.54 to 0.57, p difference in general condition of populations.

  5. The association between male-biased sex ratio and indicators of stress in red-spotted newts.

    Science.gov (United States)

    Aspbury, Andrea S; Grayson, Kristine L; Fantaye, Selamawit; Nichols, Ian; Myers-Burton, Miranda; Ortiz-Mangual, Xavier; Gabor, Caitlin R

    2017-05-01

    In populations with a male-biased operational sex ratio, coercive mating by males can have fitness consequences for females. One component of reduced fitness for females in populations with a male-biased OSR may be greater activation of the stress response, resulting in higher corticosterone release rates (CORT; a glucocorticoid stress hormone in amphibians). We test the hypothesis that a male-biased sex ratio affects female activity and release rates of CORT and testosterone (T) in male and female red-spotted newts (Notophthalmus viridescens). First, we evaluated if chemical cues from a male-biased sex ratio affect activity and CORT release rates in females. We predicted that females exposed to chemical cues of three males would be less active and have higher CORT release rates than those exposed to chemical cues of one male. Second, we measured CORT release rates of red-spotted newts in field enclosures with either a male-biased or a female-biased sex ratio. We predicted that females in the male-biased treatment would have higher CORT and T release rates than those in a female-biased treatment, owing to higher levels of male harassment. We also predicted that males would have higher CORT and T release rates in male-biased treatments due to higher levels of male-male competition. Females were not less active in response to chemical cues from more males over fewer males, but there was a positive relationship between female activity and CORT when they were exposed to the cues of three males. We also found that females, but not males, in the male-biased sex ratio treatment had higher CORT and T release rates than those in the female-biased treatment. Our results support the hypothesis that a male-biased sex ratio leads to a higher stress response, which may underlie the observed decrease in immune function and body condition in previous work exposing female red-spotted newts to a male-biased sex ratio. This study furthers our understanding of the mechanistic basis

  6. Population structure and the evolution of sexual size dimorphism and sex ratios in an insular population of Florida box turtles (Terrapene carolina bauri)

    Science.gov (United States)

    Dodd, C.K.

    1997-01-01

    Hypotheses in the chelonian literature suggest that in species with sexual size dimorphism, the smaller sex will mature at a smaller size and a younger age than the larger sex, sex ratios should be biased in favor of the earlier maturing sex, and deviations from a 1:1 sex ratio result from maturation of the smaller sex at a younger age. I tested these hypotheses using data collected from 1991 to 1995 on an insular (Egmont Key) population of Florida box turtles, Terrapene carolina bauri. Contrary to predictions, the earlier maturing sex (males) grew to larger sizes than the late maturing sex. Males were significantly larger than females in mean carapace length but not mean body mass. Sex ratios were not balanced, favoring the earlier maturing sex (1.6 males:1 female), but the sex-ratio imbalance did not result from faster maturation of the smaller sex. The imbalance in the sex ratio in Egmont Key's box turtles is not the result of sampling biases; it may result from nest placement. Size-class structure and sex ratios can provide valuable insights into the status and trends of populations of long-lived turtles.

  7. Delimitation of the embryonic thermosensitive period for sex determination using an embryo growth model reveals a potential bias for sex ratio prediction in turtles.

    Science.gov (United States)

    Girondot, Marc; Monsinjon, Jonathan; Guillon, Jean-Michel

    2018-04-01

    The sexual phenotype of the gonad is dependent on incubation temperature in many turtles, all crocodilians, and some lepidosaurians. At hatching, identification of sexual phenotype is impossible without sacrificing the neonates. For this reason, a general method to infer sexual phenotype from incubation temperatures is needed. Temperature influences sex determination during a specific period of the embryonic development, starting when the gonad begins to form. At constant incubation temperatures, this thermosensitive period for sex determination (TSP) is located at the middle third of incubation duration (MTID). When temperature fluctuates, the position of the thermosensitive period for sex determination can be shifted from the MTID because embryo growth is affected by temperature. A method is proposed to locate the thermosensitive period for sex determination based on modelling the embryo growth, allowing its precise identification from a natural regime of temperatures. Results from natural nests and simulations show that the approximation of the thermosensitive period for sex determination to the middle third of incubation duration may create a quasi-systematic bias to lower temperatures when computing the average incubation temperature during this period and thus a male-bias for sex ratio estimate. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Effects of larval-juvenile treatment with perchlorate and co-treatment with thyroxine on zebrafish sex ratios

    Science.gov (United States)

    Mukhi, S.; Torres, L.; Patino, R.

    2007-01-01

    The objective of this study was to determine the effect of larval-juvenile exposure to perchlorate, a thyroid hormone synthesis inhibitor, on the establishment of gonadal sex ratios in zebrafish. Zebrafish were exposed to untreated water or water containing perchlorate at 100 or 250 ppm for a period of 30 days starting at 3 days postfertilization (dpf). Recovery treatments consisted of a combination of perchlorate and exogenous thyroxine (T4; 10 nM). Thyroid histology was assessed at the end of the treatment period (33 dpf), and gonadal histology and sex ratios were determined in fish that were allowed an additional 10-day period of growth in untreated water. As expected, exposure to perchlorate caused changes in thyroid histology consistent with hypothyroidism and these effects were reversed by co-treatment with exogenous T4. Perchlorate did not affect fish survival but co-treatment with T4 induced higher mortality. However, relative to the corresponding perchlorate concentration, co-treatment with T4 caused increased mortality only at a perchlorate concentration of 100 ppm. Perchlorate alone or in the presence of T4 suppressed body length at 43 dpf relative to control values. Perchlorate exposure skewed the sex ratio toward female in a concentration-dependent manner, and co-treatment with T4 not only blocked the feminizing effect of perchlorate but also overcompensated by skewing the sex ratio towards male. Moreover, co-treatment with T4 advanced the onset of spermatogenesis in males. There was no clear association between sex ratios and larval survival or growth. We conclude that endogenous thyroid hormone plays a role in the establishment of gonadal sex phenotype during early development in zebrafish. ?? 2006 Elsevier Inc. All rights reserved.

  9. Patterns of repeated anal cytology results among HIV-positive and HIV-negative men who have sex with men

    Directory of Open Access Journals (Sweden)

    Hilary A. Robbins

    2018-06-01

    Full Text Available Background: Men who have sex with men (MSM are at increased risk for anal cancer. In cervical cancer screening, patterns of repeated cytology results are used to identify low- and high-risk women, but little is known about these patterns for anal cytology among MSM. Methods: We analyzed Multicenter AIDS Cohort Study (MACS data for MSM who were offered anal cytology testing annually (HIV-positive or every 2 years (HIV-negative for 4 years. Results: Following an initial negative (normal cytology, the frequency of a second negative cytology was lower among HIV-positive MSM with CD4 ≥ 500 (74% or CD4 < 500 (68% than HIV-negative MSM (83% (p < 0.001. After an initial abnormal cytology, the frequency of a second abnormal cytology was highest among HIV-positive MSM with CD4 < 500 (70% compared to CD4 ≥ 500 (53% or HIV-negative MSM (46% (p = 0.003. Among HIV-positive MSM with at least three results, 37% had 3 consecutive negative results; 3 consecutive abnormal results were more frequent among CD4 < 500 (22% than CD4 ≥ 500 (10% (p = 0.008. Conclusions: More than one-third of HIV-positive MSM have consistently negative anal cytology over three years. Following abnormal anal cytology, a repeated cytology is commonly negative in HIV-negative or immunocompetent HIV-positive men, while persistent cytological abnormality is more likely among HIV-positive men with CD4 < 500. Keywords: Anal cancer, Anal cytology, HIV, MSM, Anal cancer screening

  10. The effects of sex-ratio and density on locomotor activity in the house fly, Musca domestica

    DEFF Research Database (Denmark)

    Bahrndorff, Simon; Kjaersgaard, Anders; Pertoldi, Cino

    2012-01-01

    Although locomotor activity is involved in almost all behavioral traits, there is a lack of knowledge on what factors affect it. This study examined the effects of sex-ratio and density on the circadian rhythm of locomotor activity of adult Musca domestica L. (Diptera: Muscidae) using an infra......-red light system. Sex-ratio significantly affected locomotor activity, increasing with the percentage of males in the vials. In accordance with other studies, males were more active than females, but the circadian rhythm of the two sexes was not constant over time and changed during the light period...... of the behavioral interactions between houseflies and highlight the importance of these factors when designing behavioral experiments using M. domestica....

  11. Age at sexual maturity, sex ratio, fecundity, and longevity of isolated headwater populations of westslope cutthroat trout

    Science.gov (United States)

    Christopher C. Downs; Robert G. White; Bradley B. Shepard

    1997-01-01

    We sampled 19 isolated headwater populations of westslope cutthroat trout Oncorhynchus clarki lewisi in Montana to provide estimates of fecundity, longevity, sex ratio, and age at sexual maturity. Fecundity was estimated for 31 fish collected from two streams in the upper Missouri River drainage. Females smaller than 149 mm fork length (FL) were generally immature and...

  12. Influence of postzygotic reproductive isolation on the interspecific transmission of the paternal sex ratio chromosome in Trichogramma

    NARCIS (Netherlands)

    Jeong, G.S.; Stouthamer, R.

    2006-01-01

    The paternal sex ratio (PSR) chromosome is a supernumerary chromosome that causes the destruction of the paternal chromosome set in the first mitosis in a fertilized egg. It is known from parasitoid wasps in the genera Nasonia and Trichogramma (Hymenoptera). In these haplodiploids, the egg

  13. Sex Ratio And Size At First Maturity Of Blue Swimming Crab (Portunus pelagicus Salemo Island Pangkep Regency

    Directory of Open Access Journals (Sweden)

    Muh. Saleh Nurdin

    2016-03-01

    Full Text Available Blue swimming crab (Portunuspelagicus is aeconomical valuable fisheries importantcommodity  due to the high demand and availability jobs created for the fishermen. Due to their high demand blue swimming crab heavily exploited from Salemo Island. This study aimed at comparing the sex ratio and the size at first maturity of blue swimming crab caught in mangrove ecosystems, coral reefs, and seagrass. Sex ratio was analyzed using chi square test and the size at first maturity was analyzed using the Spearman-Karber formula. The results showed the sex ratio ofmales and femalessmall crab caught in every ecosystem is balanced. The size at first maturity of blue swimming crab caught in mangrove, seagrass and coral reefs, each to the male 81,08 mm, 102,36 mm and 102,87 mm in width and size of female 94,54 mm, 83,35 mm, 98,31 mm width. In a reference to government regulations, the blue male swimming crab caught in the coral reef and seagrass ecosystems have yet to size at first maturity is allowed to be captured. Keywords: blue swimming crab, sex ratio,size at first maturity, Salemo Island

  14. The origin of a selfish B chromosome triggering paternal sex ratio in the parasitoid wasp Trichogramma kaykai

    NARCIS (Netherlands)

    Vugt, van J.J.F.A.; Jong, de J.H.S.G.M.; Stouthamer, R.

    2009-01-01

    This study uses molecular and cytogenetic methods to determine the origin of a B chromosome in some males of the wasp Trichogramma kaykai. This so-called paternal sex ratio (PSR) chromosome transmits only through sperm and shortly after fertilization triggers degeneration of the paternal genome,

  15. Mode of action, origin and structure of the Paternal Sex Ratio chromosome in the parasitoid wasp Trichogramma kaykai

    NARCIS (Netherlands)

    Vugt, van J.J.F.A.

    2005-01-01

    Selfish genetic elements are defined as genetic elements that have a replication advantage relative to the rest of the genome. They are ubiquitous in nature and were extensively reported for almost all species studied so far. A special type of selfish genetic element, the sex ratio distorter, is

  16. Status Hierarchy, Attractiveness Hierarchy and Sex Ratio: Three Contextual Factors Explaining the Status-Aggression Link among Adolescents

    Science.gov (United States)

    Zwaan, Michiel; Dijkstra, Jan Kornelis; Veenstra, Rene

    2013-01-01

    The moderating effects of three specific conditions (status hierarchy, attractiveness hierarchy and sex ratio) on the link between status (popularity) and physical and relational aggression were examined in a large sample of adolescent boys ("N" = 1,665) and girls ("N" = 1,637) ("M" age = 13.60). In line with the…

  17. Status hierarchy, attractiveness hierarchy and sex ratio : Three contextual factors explaining the status-aggression link among adolescents

    NARCIS (Netherlands)

    Zwaan, Michiel; Dijkstra, Jan; Veenstra, René

    The moderating effects of three specific conditions (status hierarchy, attractiveness hierarchy and sex ratio) on the link between status (popularity) and physical and relational aggression were examined in a large sample of adolescent boys (N = 1,665) and girls (N = 1,637) (M age = 13.60). In line

  18. Female bias in the adult sex ratio of African annual fishes: interspecific differences, seasonal trends and environmental predictors

    Czech Academy of Sciences Publication Activity Database

    Reichard, Martin; Polačik, Matej; Blažek, Radim; Vrtílek, Milan

    2014-01-01

    Roč. 28, č. 6 (2014), s. 1105-1120 ISSN 0269-7653 R&D Projects: GA ČR(CZ) GAP506/11/0112 Institutional support: RVO:68081766 Keywords : Killifish * Tertiary sex ratio * Predator bias * Temporary savanna pools * Demographic consequences Subject RIV: EG - Zoology Impact factor: 2.517, year: 2014

  19. Reproductive behaviour of female rosy bitterling Rhodeus ocellatus in response to a female-biased operational sex ratio

    Czech Academy of Sciences Publication Activity Database

    Liao, C.; Yu, D.; Chen, Y.; Reichard, Martin; Liu, H.

    2014-01-01

    Roč. 151, č. 6 (2014), s. 755-768 ISSN 0005-7959 R&D Projects: GA ČR GBP505/12/G112 Institutional support: RVO:68081766 Keywords : alternative reproductive behaviour * female aggression * operational sex ratio * bitterling Subject RIV: EG - Zoology Impact factor: 1.230, year: 2014

  20. Mating Frequency and Effects on Sex Ratio in Female Parasitoids of xanthopimpla Stemmator (Thunberg). Implications in biological control Programmes

    International Nuclear Information System (INIS)

    Gitau, C.W.

    2002-01-01

    Cereals, especially maize and sorghum are the most important field crops in Africa. classical biological Control is a management strategy that employs natural enemies against exotic pests on cereal crops. The method has been used against Chilo partellus (Swinhoe) (Lepidoptera: Crambidae), an introduced pest of maize, using the larval parasitoid cotesia flavipes (Cameron). However, C. flavipes is not able to attack all stem borer species in targeted areas. to complement its work, Xanthopimpla stemmator has successfully been established in Mauritius on Chilo sacchariphagus (Bojer). It is a common phenomenon for haplo-diploid parasitoids to give rise to male progeny when insemination does not take place. Mating becomes important to the parasitoid population since a male biased sex ratio can bring about collapse of the population. The aim of this study was to determine wether xanthopimpla stemmator females mat more than once and wether sex ratio of progeny is affected by multiple mating in female X. stemmator. The female showed a tendency to mate once. Multiple mating did not have any significant effect on either sex ratio or longevity. More males were produced in multiple mated females than once mated females.The effect of multiple mating in X. stemmator on sex ratio in relation to biocontrol programmes are discussed

  1. The human operational sex ratio: effects of marriage, concealed ovulation, and menopause on mate competition.

    Science.gov (United States)

    Marlowe, Frank W; Berbesque, J Colette

    2012-12-01

    Among mammals, male-male competition for sexual access to females frequently involves fighting. Larger body size gives males an advantage in fighting, which explains why males tend to be larger than females in many species, including anthropoid primates. Mitani et al. derived a formula to measure the operational sex ratio (OSR) to reflect the degree of male-male competition using the number of reproductively available males to females who are cycling and capable of conceiving. The OSR should predict the degree of sexual dimorphism in body mass-at least if male-male competition involves much fighting or threatening. Here, we use hunter-gatherer demographic data and the Mitani et al. formula to calculate the human OSR. We show that humans have a much lower degree of body mass sexual dimorphism than is predicted by our OSR. We suggest this is because human competition rarely involves fighting. In human hunter-gatherer societies, differences in the ages of marriage have an impact on competition in that the age of males at first marriage is younger when there is a lower percentage of married men with two or more wives, and older when there is a higher percentage of married men with two or more wives. We discuss the implications of this for females, along with the effects of two key life history traits that influence the OSR, concealed ovulation and menopause. While menopause decreases the number of reproductively available females to males and thus increases male-male competition, concealed ovulation decreases male-male competition. Finally, we discuss the importance of mostly monogamous mate bonds in human evolution. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Effects of age and sex ratios on offspring recruitment rates in translocated black rhinoceros.

    Science.gov (United States)

    Gedir, Jay V; Law, Peter R; du Preez, Pierre; Linklater, Wayne L

    2018-06-01

    Success of animal translocations depends on improving postrelease demographic rates toward establishment and subsequent growth of released populations. Short-term metrics for evaluating translocation success and its drivers, like postrelease survival and fecundity, are unlikely to represent longer-term outcomes. We used information theory to investigate 25 years of data on black rhinoceros (Diceros bicornis) translocations. We used the offspring recruitment rate (ORR) of translocated females-a metric integrating survival, fecundity, and offspring recruitment at sexual maturity-to detect determinants of success. Our unambiguously best model (AICω = 0.986) predicted that ORR increases with female age at release as a function of lower postrelease adult rhinoceros sex ratio (males:females). Delay of first postrelease reproduction and failure of some females to recruit any calves to sexual maturity most influenced the pattern of ORRs, and the leading causes of recruitment failure were postrelease female death (23% of all females) and failure to calve (24% of surviving females). We recommend translocating older females (≥6 years old) because they do not exhibit the reproductive delay and low ORRs of juveniles (recruitment failure of juveniles and young adults (4-5.9 years old). Where translocation of juveniles is necessary, they should be released into female-biased populations, where they have higher ORRs. Our study offers the unique advantage of a long-term analysis across a large number of replicate populations-a science-by-management experiment as a proxy for a manipulative experiment, and a rare opportunity, particularly for a large, critically endangered taxon such as the black rhinoceros. Our findings differ from previous recommendations, reinforce the importance of long-term data sets and comprehensive metrics of translocation success, and suggest attention be shifted from ecological to social constraints on population growth and species recovery, particularly

  3. Behavioral tactics of male sockeye salmon (Oncorhynchus nerka) under varying operating sex ratios

    Science.gov (United States)

    Quinn, Thomas P.; Adkison, Milo D.; Ward, Michael B.

    1996-01-01

    Previous studies have demonstrated several reproductive-behavior patterns in male salmon, including competitive and sneaking tactics, the formation of hierarchies, and non-hierarchical aggregations around ripe females. Through behavioral observations at varying spatial and temporal scales, we examined the hypothesis that operational sex ratio (OSR) determines male sockeye salmon (Oncorhynchus nerka) distribution and breeding tactics. Patterns of male distribution and behavior varied over both coarse and fine scales, associated with apparent shifts in reproductive opportunities, the physical characteristics of the breeding sites, and the deterioration of the fish as they approached death. Females spawned completely within a few days of arriving on the spawning grounds, whereas males courted the available ripe females from the date of their arrival on the spawning ground until their death. This difference in reproductive lifespans tended to elevate late-season OSRs but was partially counterbalanced by male departures and the arrival of other ripe females. The proportion of males able to dominate access to ripe females decreased and the number of large courting groups increased over the course of the season, apparently related to both increasing OSR and the deteriorating physical condition of males. However, great variation in OSR was observed within the spawning sites on a given day. OSRs were generally higher in shallow than in deep water, perhaps because larger females or more desirable breeding sites were concentrated in shallow water. The aggregations of males courting females were not stable (i.e. many arrivals and departures took place) and male aggression varied with group size. Aggression was most frequent at low OSRs and in groups of intermediate size (2–4 males per female), and much less frequent in larger groups, consistent with the needs of maximizing reproductive opportunities while minimizing unproductive energy expenditure. These results indicate

  4. CHANGES IN SEX RATIO AT BIRTH IN CHINA: A DECOMPOSITION BY BIRTH ORDER.

    Science.gov (United States)

    Jiang, Quanbao; Yu, Qun; Yang, Shucai; Sánchez-Barricarte, Jesús J

    2017-11-01

    The long-term high sex ratio at birth (SRB) is a serious issue in China. In this study, changes in SRB were decomposed into variations in SRB by birth order and compositional changes in female births by birth order. With SRB data from China's surveys and censuses, and SRB data from South Korea's vital registration and censuses from 1980-2015, the trend and decomposition results in SRB were compared between China and South Korea, and the decomposition results for urban and rural SRBs, and for provinces, are presented. In both China and South Korea the rise in the SRB was driven by a rise in the SRB at all birth orders, which was only partly counteracted by the change in the distribution of births by order. The overall rise in the SRB ended when there was a decline in the SRB at second birth or above in South Korea. In China the total effect of variations in SRB of all birth orders increased more for the rural population than for the urban population before 2000, resulting in a higher total SRB for rural than urban population. After 2000, the total effect of variations in SRB of all birth orders lowered the total SRB for the rural population, whereas the effect of compositional change increased the total SRB, leading to a very slight rise in the total SRB for the rural population. At the province level, there was no spatial autocorrelation for the changes in total SRB by province, the total effect of variations in SRB of all birth orders or the effect of compositional change. The effect of variations in SRB by birth order accounted for the majority of changes in total SRB in most provinces.

  5. Superparasitism Drives Heritable Symbiont Epidemiology and Host Sex Ratio in a Wasp.

    Directory of Open Access Journals (Sweden)

    Steven R Parratt

    2016-06-01

    Full Text Available Heritable microbial symbionts have profound impacts upon the biology of their arthropod hosts. Whilst our current understanding of the dynamics of these symbionts is typically cast within a framework of vertical transmission only, horizontal transmission has been observed in a number of cases. For instance, several symbionts can transmit horizontally when their parasitoid hosts share oviposition patches with uninfected conspecifics, a phenomenon called superparasitism. Despite this, horizontal transmission, and the host contact structures that facilitates it, have not been considered in heritable symbiont epidemiology. Here, we tested for the importance of host contact, and resulting horizontal transmission, for the epidemiology of a male-killing heritable symbiont (Arsenophonus nasoniae in parasitoid wasp hosts. We observed that host contact through superparasitism is necessary for this symbiont's spread in populations of its primary host Nasonia vitripennis, such that when superparasitism rates are high, A. nasoniae almost reaches fixation, causes highly female biased population sex ratios and consequently causes local host extinction. We further tested if natural interspecific variation in superparasitism behaviours predicted symbiont dynamics among parasitoid species. We found that A. nasoniae was maintained in laboratory populations of a closely related set of Nasonia species, but declined in other, more distantly related pteromalid hosts. The natural proclivity of a species to superparasitise was the primary factor determining symbiont persistence. Our results thus indicate that host contact behaviour is a key factor for heritable microbe dynamics when horizontal transmission is possible, and that 'reproductive parasite' phenotypes, such as male-killing, may be of secondary importance in the dynamics of such symbiont infections.

  6. Marriage season, promptness of successful pregnancy and first-born sex ratio in a historical natural fertility population - evidence for sex-dependent early pregnancy loss?

    Science.gov (United States)

    Nonaka, K.; Desjardins, Bertrand; Charbonneau, Hubert; Légaré, Jacques; Miura, Teiji

    We investigated population-based vital records of the seventeenth and eighteenth century French Canadian population to assess the effects of marriage season on the outcome of the first births under natural fertility conditions (n=21,698 marriages). Promptness of the first successful conception after marriage differed according to marriage season; the proportion of marriages with a marriage-first birth interval of 8.0-10.0 months was lowest (34%) for marriages in August-October (P=0.001). Although the male/female sex ratio of the babies born with an interval of 8.0-10.0 months was generally higher (1.10) than those with an interval of 10.0-24.0 months (1.05), the marriages in August-October resulted in a significantly reduced sex ratio (0.96) among only the prompt conceptions (P=0.026). We discuss whether this seasonal reduction of the sex ratio could be partly explained by a clustered pregnancy loss of male zygotes in early pregnancy.

  7. Haldane’s Rule Is Linked to Extraordinary Sex Ratios and Sperm Length in Stalk-Eyed Flies

    Science.gov (United States)

    Wilkinson, Gerald S.; Christianson, Sarah J.; Brand, Cara L.; Ru, George; Shell, Wyatt

    2014-01-01

    We use three allopatric populations of the stalk-eyed fly Teleopsis dalmanni from Southeast Asia to test two predictions made by the sex chromosome drive hypothesis for Haldane’s rule. The first is that modifiers that suppress or enhance drive should evolve rapidly and independently in isolated populations. The second is that drive loci or modifiers should also cause sterility in hybrid males. We tested these predictions by assaying the fertility of 2066 males derived from backcross experiments involving two pairs of populations and found that the proportion of mated males that fail to produce any offspring ranged from 38 to 60% among crosses with some males producing strongly female-biased or male-biased sex ratios. After genotyping each male at 25–28 genetic markers we found quantitative trait loci (QTL) that jointly influence male sterility, sperm length, and biased progeny sex ratios in each pair of populations, but almost no shared QTL between population crosses. We also discovered that the extant XSR chromosome has no effect on sex ratio or sterility in these backcross males. Whether shared QTL are caused by linkage or pleiotropy requires additional study. Nevertheless, these results indicate the presence of a “cryptic” drive system that is currently masked by suppressing elements that are associated with sterility and sperm length within but not between populations and, therefore, must have evolved since the populations became isolated, i.e., in hybrid sterility. PMID:25164880

  8. Divorce, Abortion and Children's Sex Ratio: The Impact of Divorce Reform in China

    OpenAIRE

    Sun, Ang; Zhao, Yaohui

    2014-01-01

    This paper explores how the relative circumstances of men and women following marital dissolution affect sex-selection behavior within marriages. China's 2001 divorce reform liberalized divorce in favor of women and secured women's property rights after separation. We use this improvement in women's bargaining power in marriage for a regression discontinuity analysis of the demand for sex-selective abortions. We show that the increase in women's bargaining power reduces the propensity to have...

  9. Mapping Causes and Implications of India’s Skewed Sex Ratio and Poverty problem using Fuzzy & Neutrosophic Relational Maps

    Directory of Open Access Journals (Sweden)

    Gaurav

    2016-08-01

    Full Text Available Numerous studies by different researchers have confirmed that skewed sex ratio is a critical social problem in India. This enduring problem of gender imbalance is the collective result of factors like sex selective abortion, gender discrimination, son preference for the preservation of tribe, emergence of new technologies in medical field and many more factors. Another severe problem to be addressed in India is poverty. Many factors contribute to the perpetuation of poverty such as illiteracy, bad governance, under employment and various other reasons. Despite of India's accelerated growth rate, poverty in India is still prevalent.

  10. Regulation of gonadal sex ratios and pubertal development by the thyroid endocrine system in zebrafish (Danio rerio).

    Science.gov (United States)

    Sharma, Prakash; Patiño, Reynaldo

    2013-04-01

    We examined associations between thyroid condition, gonadal sex and pubertal development in zebrafish. Seventy-two-hour postfertilization larvae were reared in untreated medium or in the presence of goitrogens (sodium perchlorate, 0.82 mM; methimazole, 0.15 and 0.3 mM) or thyroxine (1 and 10 nM) for 30 days. Thyrocyte height, gonadal sex and gonadal development were histologically determined at 45 and 60 days postfertilization (dpf). Thyrocyte hypertrophy, an index of hypothyroidism, was observed at 45 and 60 dpf in perchlorate-treated but only at 45 dpf in methimazole-treated fish. Similarly, gonadal sex ratios were biased toward ovaries relative to control animals at 45 and 60 dpf in perchlorate-treated fish but only at 45 dpf in methimazole-treated fish. Gonadal sex ratios were biased toward testes at 45 and 60 dpf in thyroxine-treated fish. Spermatogenesis was delayed in testes from goitrogen-treated fish at 60 dpf relative to control values, but was unaffected in testes from thyroxine-treated individuals. Oogenesis seemed to be nonspecifically delayed in all treatments relative to control at 60 dpf. This study confirmed the previously reported association between hypothyroid condition and ovarian-skewed ratios, and hyperthyroid condition and testicular-skewed ratios, and also showed that male pubertal development is specifically delayed by experimental hypothyroidism. The simultaneous recovery from the hypothyroid and ovary-inducing effects of methimazole by 60 dpf (27 days post-treatment) suggests that the ovary-skewing effect of goitrogens is reversible when thyroid conditions return to basal levels before developmental commitment of gonadal sex. Conversely, the masculinizing effect of hyperthyroidism seems to be stable and perhaps permanent. Published by Elsevier Inc.

  11. High sex ratios in rural China: declining well-being with age in never-married men.

    Science.gov (United States)

    Zhou, Xudong; Hesketh, Therese

    2017-09-19

    In parts of rural China male-biased sex ratios at birth, combined with out-migration of women, have led to highly male-biased adult sex ratios, resulting in large numbers of men being unable to marry, in a culture where marriage and reproduction are an expectation. The aim of this study was to test the hypotheses that older unmarried men are more predisposed to depression, low self-esteem and aggression than both those who are married, and those who are younger and unmarried. Self-completion questionnaires were administered among men aged 20-40 in 48 villages in rural Guizhou province, southwestern China. Tools used included the Beck Depression Inventory, the Rosenberg's Self-esteem Scale and the Bryant-Smith Aggression Questionnaire. Regression models assessed psychological wellbeing while adjusting for socio-demographic variables. Completed questionnaires were obtained from 957 never-married men, 535 married men aged 30-40, 394 partnered men and 382 unpartnered men aged 20-29. After adjusting for socio-demographic variables, never-married men were more predisposed to depression ( p self-esteem ( p < 0.05) and suicidal tendencies ( p < 0.001). All the psychological measures deteriorated with age in never-married men. In contrast, married men remained stable on these dimensions with age. Never-married men are a psychologically highly vulnerable group in a society where marriage is an expectation. Since the highest birth sex-ratio cohorts have not yet reached reproductive age, the social tragedy of these men will last for at least another generation.This article is part of the themed issue 'Adult sex ratios and reproductive decisions: a critical re-examination of sex differences in human and animal societies'. © 2017 The Authors.

  12. Regulation of gonadal sex ratios and pubertal development by the thyroid endocrine system in zebrafish (Danio rerio)

    Science.gov (United States)

    Sharma, Prakash; Patino, Reynaldo

    2013-01-01

    We examined associations between thyroid condition, gonadal sex and pubertal development in zebrafish. Seventy-two-hour postfertilization larvae were reared in untreated medium or in the presence of goitrogens (sodium perchlorate, 0.82 mM; methimazole, 0.15 and 0.3 mM) or thyroxine (1 and 10 nM) for 30 days. Thyrocyte height, gonadal sex and gonadal development were histologically determined at 45 and 60 days postfertilization (dpf). Thyrocyte hypertrophy, an index of hypothyroidism, was observed at 45 and 60 dpf in perchlorate-treated but only at 45 dpf in methimazole-treated fish. Similarly, gonadal sex ratios were biased toward ovaries relative to control animals at 45 and 60 dpf in perchlorate-treated fish but only at 45 dpf in methimazole-treated fish. Gonadal sex ratios were biased toward testes at 45 and 60 dpf in thyroxine-treated fish. Spermatogenesis was delayed in testes from goitrogen-treated fish at 60 dpf relative to control values, but was unaffected in testes from thyroxine-treated individuals. Oogenesis seemed to be nonspecifically delayed in all treatments relative to control at 60 dpf. This study confirmed the previously reported association between hypothyroid condition and ovarian-skewed ratios, and hyperthyroid condition and testicular-skewed ratios, and also showed that male pubertal development is specifically delayed by experimental hypothyroidism. The simultaneous recovery from the hypothyroid and ovary-inducing effects of methimazole by 60 dpf (27 days post-treatment) suggests that the ovary-skewing effect of goitrogens is reversible when thyroid conditions return to basal levels before developmental commitment of gonadal sex. Conversely, the masculinizing effect of hyperthyroidism seems to be stable and perhaps permanent.

  13. Missing Girls in India: Infanticide, Feticide and Made-to-Order Pregnancies? Insights from Hospital-Based Sex-Ratio-at-Birth over the Last Century

    Science.gov (United States)

    Sahni, Mohit; Verma, Neeraj; Narula, D.; Varghese, Raji Mathew; Sreenivas, V.; Puliyel, Jacob M.

    2008-01-01

    Background There are 44 million missing women in India. Gender bias; neglect of girls, infanticides and feticides are responsible. The sex ratio at birth can be used to examine the influence of antenatal sex selection on the sex ratio. Materials and Methods Records from 321,991 deliveries at one hospital over 11 decades were utilized. The middle year in each decade was taken as representative of the decade. Data from 33,524 deliveries were then analyzed. Data for each decade was combined with that of previous decades and compared to the data of subsequent decades to look for any change in the trend. Sex ratio in the second children against sex of the first child was studied separately. Results The mean sex ratio for the 110 years examined was 910 girls to 1000 boys (95% CI; 891 to 930). The sex ratio dropped significantly from 935 (CI: 905 to 967) before 1979, to 892 (CI: 868 to 918) after 1980 (P = 0.04). The sex ratio in the second child was significantly lower if the first child was a girl [716 (CI: 672 to 762] (P<0.001). On the other hand, there was an excess of girls born to mothers whose first child was boy [1140 girls per 1000 boys (CI: 1072 to 1212 P<0.001)]. Conclusions The sex ratio fell significantly after 1980 when ultra sound machines for antenatal sex determination became available. The sex ratio in second children if the first was a girl was even lower. Sex selective abortions after antenatal sex determination are thus implicated. However data on second children especially the excess of girls born to mothers who have a previous boy seen in the decade before the advent of antenatal ultra sound machines, suggests that other means of sex selection are also used. PMID:18493614

  14. On the masculinization of population: The contribution of demographic development -- A look at sex ratios in Sweden over 250 years

    Directory of Open Access Journals (Sweden)

    Thomas Spoorenberg

    2016-06-01

    Full Text Available Background: Almost everywhere, women live longer than men, but the world population includes increasingly more men than women. This fact is observed not only in populations where gender-based discrimination is practised, but also in developed countries like Sweden. Objective: Whereas discrimination against female infants and women is usually given as an explanation for this paradox, demographic development (through improved survival also plays a role. This study examines the largely unnoticed role of demographic development in the masculinization of population, taking the case of Sweden. Methods: Using high-quality data from the Human Mortality Database for Sweden over the last 250 years, changes in the sex ratio at various ages are described and linked to the continuing survival gains achieved over the mortality transition. Results: Thanks to the reduction of secular mortality in Sweden, the natural sex imbalance observed at birth has been progressively prolonged later in life, and the age at which women outnumber men has been postponed to older ages. Similar developments are found in Norway and Denmark. Conclusions: The general decline of mortality is one of humanity's biggest achievements, but the accompanying change in age- and sex-specific survival patterns, coupled with the natural sex imbalance at birth, influences the age and sex composition of a population and, therefore, the sex ratio at successive ages. In a world where each new generation can expect to enjoy a longer life than the previous one, an increasing number of men can also be expected. Contribution: The role of demographic development in the masculinization of population has remained largely unnoticed so far.

  15. Changing trend? Sex ratios of children born to Indian immigrants in Norway revisited.

    Science.gov (United States)

    Tønnessen, Marianne; Aalandslid, Vebjørn; Skjerpen, Terje

    2013-09-05

    In some Western countries, a disturbingly low share of girls has been observed among new-borns from Indian immigrants. Also in Norway, a previous study based on figures from 1969-2005 showed a high percentage of boys among children of Indian origin living in Norway, when the birth was of higher order (third birth or later). This was suggested to reflect a practice of sex-selective abortions in the Indian immigrant population. In this article we have seen whether extended time series for the period 2006-2012 give further support to this claim. Based on data from the Norwegian Central Population Register we used observations for the sex of all live births in Norway for the period 1969-2012 where the mother was born in India. The percentage of boys was calculated for each birth order, during four sub periods. Utilising a binomial probability model we tested whether the observed sex differences among Indian-born women were significantly different from sex differences among all births. Contrary to findings from earlier periods and other Western countries, we found that Indian-born women in Norway gave birth to more girls than boys of higher order in the period 2006-2012. This is somewhat surprising, since sex selection is usually expected to be stronger if the mother already has two or more children. The extended time series do not suggest a prevalence of sex selective abortions among Indian-born women in Norway. We discuss whether the change from a majority of boys to a majority of girls in higher order could be explained by new waves of immigrant women, by new preferences among long-residing immigrant women in Norway - or by mere coincidence.

  16. Induction of inherited sterility and sex ratio distribution due to exposure to substerilising doses of gamma radiation in cotton bollworm Earias vittella fabricius

    International Nuclear Information System (INIS)

    Tamhankar, A.J.; Shantharam, K.

    2005-01-01

    Substerilising doses of gamma radiation induced inherited sterility and sex ratio distortion in the cotton bollworm Earias vittella fabricius. Adults irradiated with 75 Gy and self-crossed, provided sterile F 1 adults, suitable for direct use in sterile insect technique (SIT). In case of 50 Gy, the F 1 adults, when backcrossed, produced F 2 progeny with sex ratio in favour of females (1: >3). With 25 Gy, a sex ratio distortion was recorded in F 1 (1 male: 2.25 females) and self-crossing of F 1 resulted in progeny with a sex ratio of 3:1. Backcrossing of the F 1 female produced F 2 progeny with a sex ratio of 1:5. These results have implications in improving cost/benefit ratio of SIT for this species. (author)

  17. Missing girls in India: infanticide, feticide and made-to-order pregnancies? Insights from hospital-based sex-ratio-at-birth over the last century.

    Science.gov (United States)

    Sahni, Mohit; Verma, Neeraj; Narula, D; Varghese, Raji Mathew; Sreenivas, V; Puliyel, Jacob M

    2008-05-21

    There are 44 million missing women in India. Gender bias; neglect of girls, infanticides and feticides are responsible. The sex ratio at birth can be used to examine the influence of antenatal sex selection on the sex ratio. Records from 321,991 deliveries at one hospital over 11 decades were utilized. The middle year in each decade was taken as representative of the decade. Data from 33,524 deliveries were then analyzed. Data for each decade was combined with that of previous decades and compared to the data of subsequent decades to look for any change in the trend. Sex ratio in the second children against sex of the first child was studied separately. The mean sex ratio for the 110 years examined was 910 girls to 1000 boys (95% CI; 891 to 930). The sex ratio dropped significantly from 935 (CI: 905 to 967) before 1979, to 892 (CI: 868 to 918) after 1980 (P = 0.04). The sex ratio in the second child was significantly lower if the first child was a girl [716 (CI: 672 to 762] (Psex ratio fell significantly after 1980 when ultra sound machines for antenatal sex determination became available. The sex ratio in second children if the first was a girl was even lower. Sex selective abortions after antenatal sex determination are thus implicated. However data on second children especially the excess of girls born to mothers who have a previous boy seen in the decade before the advent of antenatal ultra sound machines, suggests that other means of sex selection are also used.

  18. Seasonal variation in Eurasian Wigeon Anas penelope sex and age ratios from hunter-based surveys

    DEFF Research Database (Denmark)

    Clausen, Kevin Kuhlmann; Dalby, Lars; Sunde, Peter

    2013-01-01

    dominated by adult males, and juvenile proportions were highest in November and significantly lower before and after this peak. Nationwide field assessments undertaken in January 2012 showed no significant differences from sex and age ratios in the wing survey data from that particular hunting season (2011...... schemes. This study found consistent seasonal variation in Eurasian Wigeon Anas penelope sex and age ratios among Danish hunter-based wing surveys, and describes how accounting for this variation might explain reported discrepancies between this and other monitoring methods. Early season flocks were....../2012), indicating that this survey is a good predictor of Wigeon demography. These results highlight the need to account for consistent temporal variation in such demographic time series when using the results to model population parameters....

  19. Germ-line origins of mutation in families with hemophilia B: The sex ratio varies with the type of mutation

    Energy Technology Data Exchange (ETDEWEB)

    Ketterling, R.P.; Vielhaber, E.; Bottema, C.D.K.; Schaid, D.J.; Sommer, S.S. (Mayo Clinic/Foundation, Rochester, MN (United States)); Cohen, M.P. (Vanderbilt Univ., Nashville, TN (United States)); Sexauer, C.L. (Children' s Hospital, Oklahoma City, OK (United States))

    1993-01-01

    Previous epidemiological and biochemical studies have generated conflicting estimates of the sex ratio of mutation. Direct genomic sequencing in combination with haplotype analysis extends previous analyses by allowing the precise mutation to be determined in a given family. From analysis of the factor IX gene of 260 consecutive families with hemophilia B, the authors report the germ-line origin of mutation in 25 families. When combined with 14 origins of mutation reported by others and with 4 origins previously reported by them, a total of 25 occur in the female germ line, and 18 occur in the male germ line. The excess of germ-line origins in females does not imply an overall excess mutation rate per base pair in the female germ line. Bayesian analysis of the data indicates that the sex ratio varies with the type of mutation. The aggregate of single-base substitutions shows a male predominance of germ-line mutations (P < .002). The maximum-likelihood estimate of the male predominance is 3.5-fold. Of the single-base substitutions, deletions display a sex ratio of unity. Analysis of the parental age at transmission of a new mutation suggests that germ-line mutations are associated with a small increase in parental age in females but little, if any, increase in males. Although direct genomic sequencing offers a general method for defining the origin of mutation in specific families, accurate estimates of the sex ratios of different mutational classes require large sample sizes and careful correction for multiple biases of ascertainment. The biases in the present data result in an underestimate of the enhancement of mutation in males. 62 refs., 1 fig., 5 tabs.

  20. [Sex ratio and environmental influence on population growth rate of Callinectes bellicosus (Decapoda: Portunidae) in the Gulf of California].

    Science.gov (United States)

    Rodríguez-Félix, Demetrio; Cisneros-Mata, Miguel Angel; Aragón-Noriega, Eugenio Alberto; Arreola-Lizárraga, José Alfredo

    2016-09-01

    The brown swimming crab (Callinectes bellicosus) is an economically important species in the Gulf of California, and its fishing activity, held in Sonora from 1986, has been affected by a 20-year declining trend in its biomass. With the aim to understand the possible reasons of this species population changes along time, we estimated population growth rate (r) and sex ratio of C. bellicosus, and combined them with three parameters describing its habitat: sea temperature, wetland extension and habitat size in four areas along the coast of Sonora. For this, monthly mean sex ratio was estimated from crabs samples obtained from commercial catches during 1998-2002 and 2012; mean sea surface temperature for the spawning period (May-August) were derived from remote sensors for the same years; while wetland coverages were obtained from published reports, and habitat size was estimated as the fishing surface. For each area, r was estimated using a method developed for limited data situations using commercial landings (t) from 1986-2013. With data from the four areas, simple and multiple linear regression models were developed to ascertain theoretical sensitivities of r to variations in sex ratio and environmental parameters. A total of 24 556 crabs were sampled; males dominated (68.8 %) over females during the study period and in all areas; a cluster analysis identified two groups according to sex ratio: a Northern group with zones 1 and 2, and a Southern group with zones 3 and 4. r values were different in all zones (P0.995). Both the estimated data and sensitivity analyses suggest the existence of a direct and positive dependence of r on the proportion of female crabs and wetland size. We hypothesize that excess fishing of females caused the declining biomass trend of the brown swimming crab in Sonora, and concluded on the convenience of implementing harvest refugia inside coastal wetlands to protect females during the spawning season.

  1. Sex-ratio control erodes sexual selection, revealing evolutionary feedback from adaptive plasticity

    NARCIS (Netherlands)

    Fawcett, Tim W.; Kuijper, Bram; Weissing, Franz J.; Pen, Ido

    2011-01-01

    Female choice is a powerful selective force, driving the elaboration of conspicuous male ornaments. This process of sexual selection has profound implications for many life-history decisions, including sex allocation. For example, females with attractive partners should produce more sons, because

  2. Effect of time of artificial insemination on embryo sex ratio in dairy cattle

    NARCIS (Netherlands)

    Roelofs, J.B.; Bouwman, E.B.; Pedersen, H.G.; Riestra Rasmussen, Z.; Soede, N.M.; Thomsen, P.D.; Kemp, B.

    2006-01-01

    The objective of the present study was to examine whether different intervals between insemination and ovulation have an influence on the sex of seven-day-old embryos in dairy cattle. Cows were inseminated once with semen of one of two bulls of proven fertility between 36 h before ovulation and 12 h

  3. Analysis of case-parent trios for imprinting effect using a loglinear model with adjustment for sex-of-parent-specific transmission ratio distortion

    DEFF Research Database (Denmark)

    Huang, Lam Opal; Infante-Rivard, Claire; Labbe, Aurélie

    2017-01-01

    Transmission ratio distortion (TRD) is a phenomenon where parental transmission of disease allele to the child does not follow the Mendelian inheritance ratio. TRD occurs in a sex-of-parent-specific or non-sex-of-parent-specific manner. An offset computed from the transmission probability of the ...

  4. Second to fourth digit ratio, sex differences and antropometric measuments: their relationship in children.

    Science.gov (United States)

    Uludag, Aysegul; Tekin, Murat; Ertekin, Yusuf H; Şahin, Erkan M; Cevizci, Sibel; Cibik, Birol; Oguz, Sevilay; Erbag, Oznur

    2017-04-01

    The aim of this study was to determine the effect of socio-demographic factors and anthropometric measurements on 2/4 digit ratio in the school aged children. This cross-sectional study was completed in primary and secondary schools in the city center of Canakkale, Turkey. The students were seated at a table by the responsible doctor, and were asked to extend the palm of the right and left hand in the schools. Using a Vernier Caliper the 2/4 fingers were measured from the palm twice, and the results were noted together with socio-demographic information. Weight, length, waist and hip measurements were taken while students were behind a folding screen. A total of 1860 students from 5-14 years were included in the study. The right hand 2/4 digit ratio was 0.9765±0.035 and the left hand ratio was 0.9716±0.036 for girls. For the boys the ratios were 0.9688±0.035 for right hand and 0.9653±0.033 for left hand. The digit ratios of girls were significantly higher than boys and the right hand ratio was even greater. The 2/4 digit measurements of both hands of students were positively correlated with each other. In regression model left hand 2/4 ratio is dependent hip circumference, monthly income and gender as adjusted r2 0.051. The right hand 2/4 ratio was dependent gender, monthly income, hip circumference and birthweight as adjusted r2 0.041. The 2/4 digit ratio of school-aged in Turkish children differed based on gender. Digit ratios depend on the hip circumference, gender (girls have higher ratio), birthweight, gestation week and monthly income. Further research, especially the effect of monthly income, is needed.

  5. Polybrominated diphenyl ethers affect the reproduction and development, and alter the sex ratio of zebrafish (Danio rerio)

    International Nuclear Information System (INIS)

    Han, X.B.; Yuen, Karen W.Y.; Wu, Rudolf S.S.

    2013-01-01

    Polybrominated diphenyl ethers (PBDEs) have been commonly used as flame retardants and now become ubiquitous in the global environment. Using zebrafish as a model, we tested the hypothesis that PBDEs may affect the reproduction and development of fish. Zebrafish were exposed to environmentally relevant concentrations of DE-71 (a congener of PBDE commonly found in the environment) throughout their whole life cycle, and the effects of DE-71 on gonadal development, gamete quality, fertilization success, hatching success, embryonic development and sex ratio were investigated. Despite gonadal development was enhanced, reductions in spawning, fertilization success, hatching success and larval survival rate were evident, while significant increases in malformation and percentage of male were also observed in the F1 generation. Our laboratory results suggest that PBDEs may pose a risk to reproductive success and alter the sex ratio of fish in environments highly contaminated with PBDEs. -- Highlights: •Zebrafish were exposed to PBDE from eggs to adults. •An increase in Gonadal-Somatic Index and enhanced gonadal development was enhanced. •Fertilization and hatching successes were reduced, while malformation was increased. •PBDE alters sex differentiation, leading to a male biased F1 population. •Environmental relevant concentrations of PBDE threaten natural fish populations. -- PBDE reduces fertilization and hatching successes, causes malformation and leads to a male biased F1 generation in fish

  6. ACC oxidase and miRNA 159a, and their involvement in fresh fruit bunch yield (FFB) via sex ratio determination in oil palm.

    Science.gov (United States)

    Somyong, Suthasinee; Poopear, Supannee; Sunner, Supreet Kaur; Wanlayaporn, Kitti; Jomchai, Nukoon; Yoocha, Thippawan; Ukoskit, Kittipat; Tangphatsornruang, Sithichoke; Tragoonrung, Somvong

    2016-06-01

    Oil palm (Elaeis guineesis Jacq.) is the most productive oil-bearing crop, yielding more oil per area than any other oil-bearing crops. However, there are still efforts to improve oil palm yield, in order to serve consumer and manufacturer demand. Oil palm produces female and male inflorescences in an alternating cycle. So, high sex ratio (SR), the ratio of female inflorescences to the total inflorescences, is a favorable trait in term of increasing yields in oil palm. This study aims to understand the genetic control for SR related traits, such as fresh fruit bunch yield (FFB), by characterizing genes at FFB quantitative trait loci (QTLs) on linkage 10 (chromosome 6) and linkage 15 (chromosome 10). Published oil palm sequences at the FFB QTLs were used to develop gene-based and simple sequence repeat (SSR) markers. We used the multiple QTL analysis model (MQM) to characterize the relationship of new markers with the SR traits in the oil palm population. The RNA expression of the most linked QTL genes was also evaluated in various tissues of oil palm. We identified EgACCO1 (encoding aminocyclopropane carboxylate (ACC) oxidase) at chromosome 10 and EgmiR159a (microRNA 159a) at chromosome 6 to be the most linked QTL genes or determinants for FFB yield and/or female inflorescence number with a phenotype variance explained (PVE) from 10.4 to 15 % and suggest that these play the important roles in sex determination and differentiation in oil palm. The strongest expression of EgACCO1 and the predicted precursor of EgmiR159a was found in ovaries and, to a lesser extent, fruit development. In addition, highly normalized expression of EgmiR159a was found in female flowers. In summary, the QTL analysis and the RNA expression reveal that EgACCO1 and EgmiR159a are the potential genetic factors involved in female flower determination and hence would affect yield in oil palm. However, to clarify how these genetic factors regulate female flower determination, more investigation

  7. Pre-conception energy balance and secondary sex ratio--partial support for the Trivers-Willard hypothesis in dairy cows.

    Science.gov (United States)

    Roche, J R; Lee, J M; Berry, D P

    2006-06-01

    According to the Trivers-Willard hypothesis, maternal condition at or around conception affects the secondary sex ratio in mammals. However, there are little or no data available on indicators of maternal condition in dairy cows on the sex of the resultant offspring. A total of 76,607 body condition score (BCS; scale of 1 to 5) records and 76,611 body weight (BW) records from 3,209 lactations across 1,172 cows were extracted from a research database collated from one research herd between 1986 and 2004, inclusive. Exclusion of multiple births and cows with no information before calving (e.g., nulliparous animals) resulted in 2,029 records with BCS and BW observations from the previous calving, and 2,002 and 1,872 lactations with BCS and BW observations at conception and midgestation, respectively. Change in BCS and BW between calving and conception and between conception and midgestation was calculated per lactation. Generalized estimating equations were used to model the logit of the probability of a male calf, in which cow was included as a repeated effect with a first-order autoregressive correlation structure assumed among records within cow. Of the BCS variables investigated, there was a linear relationship between the logit of the probability of a male calf and BCS change between calving and conception, the rate of BCS change over this period (BCS divided by days in milk), and BCS at the calving event immediately before conception. The birth of a bull calf was 1.85 times more likely in cows that lost no BCS from calving to conception compared with cows that lost one BCS unit from calving to conception. This increase in odds was equivalent to a 14% unit increase in the probability of a male calf (from 54 to 68%). The amount of BW lost between calving and conception and the rate of loss affected the sex of the resultant offspring. Less BW loss or greater BW gain between calving and conception was associated with greater likelihood of a male calf. Results

  8. Transcriptome profiling of Nasonia vitripennis testis reveals novel transcripts expressed from the selfish B chromosome, paternal sex ratio.

    Science.gov (United States)

    Akbari, Omar S; Antoshechkin, Igor; Hay, Bruce A; Ferree, Patrick M

    2013-09-04

    A widespread phenomenon in nature is sex ratio distortion of arthropod populations caused by microbial and genetic parasites. Currently little is known about how these agents alter host developmental processes to favor one sex or the other. The paternal sex ratio (PSR) chromosome is a nonessential, paternally transmitted centric fragment that segregates in natural populations of the jewel wasp, Nasonia vitripennis. To persist, PSR is thought to modify the hereditary material of the developing sperm, with the result that all nuclear DNA other than the PSR chromosome is destroyed shortly after fertilization. This results in the conversion of a fertilized embryo--normally a female--into a male, thereby insuring transmission of the "selfish" PSR chromosome, and simultaneously leading to wasp populations that are male-biased. To begin to understand this system at the mechanistic level, we carried out transcriptional profiling of testis from WT and PSR-carrying males. We identified a number of transcripts that are differentially expressed between these conditions. We also discovered nine transcripts that are uniquely expressed from the PSR chromosome. Four of these PSR-specific transcripts encode putative proteins, whereas the others have very short open reading frames and no homology to known proteins, suggesting that they are long noncoding RNAs. We propose several different models for how these transcripts could facilitate PSR-dependent effects. Our analyses also revealed 15.71 MB of novel transcribed regions in the N. vitripennis genome, thus increasing the current annotation of total transcribed regions by 53.4%. Finally, we detected expression of multiple meiosis-related genes in the wasp testis, despite the lack of conventional meiosis in the male sex.

  9. Exposure to persistent organic pollutants and sperm sex chromosome ratio in men from the Faroe Islands

    DEFF Research Database (Denmark)

    Kvist, L; Giwercman, A; Weihe, P

    2014-01-01

    People in the Arctic as well as fishermen on the polluted Swedish east coast are highly exposed to persistent organic pollutants (POPs). These compounds have been shown to affect the sperm Y:X chromosome ratio. In present study, the aim was to investigate whether polychlorinated biphenyl (PCB......,p'-DDE and ΣPCB correlated significantly (r=0.927, pboth Inuit and Swedish fishermen (0.512 for both......). In conclusion, Faroese men presented with lower Y:X ratio than Greenland Inuit and Swedish fishermen. Although no direct health effects are expected due to the lower Faroese Y:X ratio, it could be indicative of adverse effects on the reproductive system....

  10. Second to fourth digit ratio (2D:4D and concentrations of circulating sex hormones in adulthood

    Directory of Open Access Journals (Sweden)

    Morris Howard A

    2011-04-01

    Full Text Available Abstract Background The second to fourth digit ratio (2D:4D is used as a marker of prenatal sex hormone exposure. The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:4D. Methods This analysis was based on a random sample from the Melbourne Collaborative Cohort Study. The sample consisted of of 1036 men and 620 post-menopausal women aged between 39 and 70 at the time of blood draw. Concentrations of circulating sex hormones were measured from plasma collected at baseline (1990-1994, while digit length was measured from hand photocopies taken during a recent follow-up (2003-2009. The outcome measures were circulating concentrations of testosterone, oestradiol, dehydroepiandrosterone sulphate, androstenedione, Sex Hormone Binding Globulin, androstenediol glucoronide for men only and oestrone sulphate for women only. Free testosterone and oestradiol were estimated using standard formulae derived empirically. Predicted geometric mean hormone concentrations (for tertiles of 2D:4D and conditional correlation coefficients (for continuous 2D:4D were obtained using mixed effects linear regression models. Results No strong associations were observed between 2D:4D measures and circulating concentrations of hormones for men or women. For males, right 2D:4D was weakly inversely associated with circulating testosterone (predicted geometric mean testosterone was 15.9 and 15.0 nmol/L for the lowest and highest tertiles of male right 2D:4D respectively (P-trend = 0.04. There was a similar weak association between male right 2D:4D and the ratio of testosterone to oestradiol. These associations were not evident in analyses of continuous 2D:4D. Conclusions There were no strong associations between any adult circulating concentration of sex hormone or SHGB and 2D:4D. These results contribute to the growing body of evidence indicating that 2D:4D is unrelated to adult sex

  11. Repeat migration and disappointment.

    Science.gov (United States)

    Grant, E K; Vanderkamp, J

    1986-01-01

    This article investigates the determinants of repeat migration among the 44 regions of Canada, using information from a large micro-database which spans the period 1968 to 1971. The explanation of repeat migration probabilities is a difficult task, and this attempt is only partly successful. May of the explanatory variables are not significant, and the overall explanatory power of the equations is not high. In the area of personal characteristics, the variables related to age, sex, and marital status are generally significant and with expected signs. The distance variable has a strongly positive effect on onward move probabilities. Variables related to prior migration experience have an important impact that differs between return and onward probabilities. In particular, the occurrence of prior moves has a striking effect on the probability of onward migration. The variable representing disappointment, or relative success of the initial move, plays a significant role in explaining repeat migration probabilities. The disappointment variable represents the ratio of actural versus expected wage income in the year after the initial move, and its effect on both repeat migration probabilities is always negative and almost always highly significant. The repeat probabilities diminish after a year's stay in the destination region, but disappointment in the most recent year still has a bearing on the delayed repeat probabilities. While the quantitative impact of the disappointment variable is not large, it is difficult to draw comparisons since similar estimates are not available elsewhere.

  12. Effects of a sex-ratio distorting endosymbiont on mtDNA variation in a global insect pest

    Directory of Open Access Journals (Sweden)

    Cook James M

    2009-03-01

    Full Text Available Abstract Background Patterns of mtDNA variation within a species reflect long-term population structure, but may also be influenced by maternally inherited endosymbionts, such as Wolbachia. These bacteria often alter host reproductive biology and can drive particular mtDNA haplotypes through populations. We investigated the impacts of Wolbachia infection and geography on mtDNA variation in the diamondback moth, a major global pest whose geographic distribution reflects both natural processes and transport via human agricultural activities. Results The mtDNA phylogeny of 95 individuals sampled from 10 countries on four continents revealed two major clades. One contained only Wolbachia-infected individuals from Malaysia and Kenya, while the other contained only uninfected individuals, from all countries including Malaysia and Kenya. Within the uninfected group was a further clade containing all individuals from Australasia and displaying very limited sequence variation. In contrast, a biparental nuclear gene phylogeny did not have infected and uninfected clades, supporting the notion that maternally-inherited Wolbachia are responsible for the mtDNA pattern. Only about 5% (15/306 of our global sample of individuals was infected with the plutWB1 isolate and even within infected local populations, many insects were uninfected. Comparisons of infected and uninfected isofemale lines revealed that plutWB1 is associated with sex ratio distortion. Uninfected lines have a 1:1 sex ratio, while infected ones show a 2:1 female bias. Conclusion The main correlate of mtDNA variation in P. xylostella is presence or absence of the plutWB1 infection. This is associated with substantial sex ratio distortion and the underlying mechanisms deserve further study. In contrast, geographic origin is a poor predictor of moth mtDNA sequences, reflecting human activity in moving the insects around the globe. The exception is a clade of Australasian individuals, which may

  13. Digit ratio (2D:4D) and social integration: an effect of prenatal sex hormones

    Czech Academy of Sciences Publication Activity Database

    Kovářík, Jaromír; Brañas-Garza, P.; Davidson, M. W.; Haim, D. A.; Carcelli, S.; Fowler, J. H.

    2017-01-01

    Roč. 5, č. 4 (2017), s. 476-489 ISSN 2050-1242 R&D Projects: GA ČR(CZ) GA14-22044S Institutional support: RVO:67985998 Keywords : social networks * digit ratio * prenatal and rogens Subject RIV: AH - Economics OBOR OECD: Applied Economics, Econometrics

  14. Sex ratio and breeding of white-lipped peccaries Tayassu pecari (Artiodactyla: Tayassuidae in a Costa Rican rain forest

    Directory of Open Access Journals (Sweden)

    Mariana Altrichter

    2001-03-01

    Full Text Available White-lipped peccaries are non-seasonal breeders in South America, but little is known about their reproduction in Central America. There are few studies about the sex ratio of this species in the field. We studied the reproduction and sex ratio of white-lipped peccaries during 200 hours of field observation of four radiomarked and two unmarked herds, from July 1996 to April 1997, in Corcovado National Park, Costa Rica. Sex ratio data of three additional, radiomarked herds observed in 1998 were also included. We recorded numbers of mountings, presence of newborns and numbers of nursing interactions. The peccaries showed a distinct reproductive seasonality, with one mating peak in February and another in July. The greatest number of newborns and the peak in nursing activity were observed during July and August, when fruit availability for the peccaries was high. The adult sex ratio was significantly female biased (1.4:1 - 1.8:1, also in contrast with South American populations.Los "chanchos cariblancos" Tayassu pecari no son reproductores estacionales en Sur América. En Centro América se conoce muy poco sobre la reproducción de esta especie en la naturaleza. Estudiamos reproducción y la proporción de sexos durante 200 horas de observación de cuatro manadas marcadas con radiocollares y de dos manadas sin marcar, desde julio de 1996 hasta abril de 1997 en el Parque Nacional Corcovado, Costa Rica, agregando datos de proporción sexual de tres manadas observadas en 1998. Registramos el número de cópulas y de amamantamientos, así como la presencia de recién nacidos en las manadas. Observamos una marcada estacionalidad en la reproducción, con un pico en el número de cópulas en febrero y otro en julio. La mayor cantidad de recién nacidos y el pico de actividad de amamantamiento fueron en julio y agosto, cuando la disponibilidad de alimento era alta. Entre adultos predominaron numéricamente las hembras (1.4:1 - 1.8:1, lo cual difiere de lo

  15. The effects of cavity length on nest size, sex ratio and mortality of Centris (Heterocentris) analis (Hymenoptera, Apidae, Centridini)

    OpenAIRE

    Alonso , Juliana; Silva , Janaina; Garófalo , Carlos

    2012-01-01

    International audience; This study investigated the effects of different cavity lengths in trap-nests on the number of cells constructed per nest, sex ratio and mortality of offspring of Centris analis at three sites in Ribeirão Preto, São Paulo, Brazil. Cavity length did not affect the occupation rates of the trap-nests, with the exception of a preference for the shortest trap-nests found at one site. The number of cells per nest increased with trap-nest length. Cavity length affected neithe...

  16. Digit ratio (2D:4D) and social integration: an effect of prenatal sex hormones

    OpenAIRE

    Kovářík, Jaromír; Branas-Garza, Pablo; Davidson, Michael W.; Haim, Dotan A.; Carcelli, Shannon; Fowler, James H.

    2017-01-01

    The position people occupy in their social and professional networks is related to their social status and has strong effects on their access to social resources. While attainment of particular positions is driven by behavioral traits, many biological factors predispose individuals to certain behaviors and motivations. Prior work on exposure to fetal androgens (measured by second-to-fourth digit ratio, 2D:4D) shows that it correlates with behaviors and traits related to social status, which m...

  17. Association of UV radiation with multiple sclerosis prevalence and sex ratio in France.

    Science.gov (United States)

    Orton, S-M; Wald, L; Confavreux, C; Vukusic, S; Krohn, J P; Ramagopalan, S V; Herrera, B M; Sadovnick, A D; Ebers, G C

    2011-02-01

    French farmers and their families constitute an informative population to study multiple sclerosis (MS) prevalence and related epidemiology. We carried out an ecological study to evaluate the association of MS prevalence and ultraviolet (UV) radiation, a candidate climatologic risk factor. Mean annual and winter (December-March) UVB irradiation values were systematically compared to MS prevalence rates in corresponding regions of France. UVB data were obtained from the solar radiation database (SoDa) service and prevalence rates from previously published data on 2,667 MS cases registered with the national farmer health insurance system, Mutualité Sociale Agricole (MSA). Pearson correlation was used to examine the relationship of annual and winter UVB values with MS prevalence. Male and female prevalence were also analyzed separately. Linear regression was used to test for interaction of annual and winter UVB with sex in predicting MS prevalence. There was a strong association between MS prevalence and annual mean UVB irradiation (r = -0.80, p role for gender-specific effects of UVB exposure.

  18. Female biased sex-ratio in Schistosoma mansoni after exposure to an allopatric intermediate host strain of Biomphalaria glabrata.

    Science.gov (United States)

    Lepesant, Julie M J; Boissier, Jérôme; Climent, Déborah; Cosseau, Céline; Grunau, Christoph

    2013-10-01

    For parasites that require multiple hosts to complete their development, the interaction with the intermediate host may have an impact on parasite transmission and development in the definitive host. The human parasite Schistosoma mansoni needs two different hosts to complete its life cycle: the freshwater snail Biomphalaria glabrata (in South America) as intermediate host and a human or rodents as final host. To investigate the influence of the host environment on life history traits in the absence of selection, we performed experimental infections of two B. glabrata strains of different geographic origin with the same clonal population of S. mansoni. One B. glabrata strain is the sympatric host and the other one the allopatric host. We measured prevalence in the snail, the cercarial infectivity, sex-ratio, immunopathology in the final host and microsatellite frequencies of individual larvae in three successive generations. We show that, even if the parasite population is clonal based on neutral markers, S. mansoni keeps the capacity of generating phenotypic plasticity and/or variability for different life history traits when confront to an unusual environment, in this study the intermediate host. The most dramatic change was observed in sex-ratio: in average 1.7 times more female cercariae were produced when the parasite developed in an allopatric intermediate host. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Data storage on Russian pesticide producers exposed to dioxin. Sex ratios of third generation of Russian cohort

    Energy Technology Data Exchange (ETDEWEB)

    Amirova, Z.; Kruglov, E. [Environmental Research and Protection Center, Ufa (Russian Federation); Dardynskaia, I. [Univ. of Illinois, School of Public Health, Chicago (United States)

    2004-09-15

    A cohort of Russian workers who produced 2,4,5-T and 2,4,5-TrCP at a chemical factory in Ufa was brought to light in the papers of A. Schecter, J. Ryan and O. Papke. Dioxin exposure was experimentally confirmed by PCDD/Fs determination in blood samples first for a small group of workers and their children. This study permitted to connect the information of medical institutions about chloracne from which a group of young 2,4,5-T workers suffered in 1965-67 with exposure to dioxin. This report presents the results of the detailed study of the third generation of the Russian cohort (247 workers, 314 children and 260 grandchildren). We also present the data on the sex ratio of the second generation for the initial group enlarged by 25% as compared with the group of workers analyzed by J. Ryan et al. (198 workers and 227 children). Besides, as skewed sex ratio had earlier been stated only for paternal descendants, genealogical branches of the cohort representatives were studied.

  20. Sex ratio, poverty, and concurrent partnerships among men and women in the United States: a multilevel analysis.

    Science.gov (United States)

    Adimora, Adaora A; Schoenbach, Victor J; Taylor, Eboni M; Khan, Maria R; Schwartz, Robert J; Miller, William C

    2013-11-01

    Social and economic contextual factors may promote concurrent sexual partnerships, which can accelerate population HIV transmission and are more common among African Americans than U.S. Whites. We investigated the relationship between contextual factors and concurrency. We analyzed past 12-month concurrency prevalence in the 2002 National Survey of Family Growth and its contextual database in relation to county sex ratio (among respondent's racial and ethnic group), percentage in poverty (among respondent's racial and ethnic group), and violent crime rate. Analyses examined counties with balanced (0.95-1.05 males/female) or low (poverty (OR, 1.18; 95% CI, 0.98-1.42 per 10 percentage-point increase), and higher crime rates (OR, 1.04; 95% CI, 1.00-1.09 per 1000 population/year). Notably, 99.5% of Whites and 93.7% of Hispanics, but only 7.85% of Blacks, lived in balanced sex ratio counties; about 5% of Whites, half of Hispanics, and three-fourths of Blacks resided in counties with >20% same-race poverty. The dramatic Black-White differences in contextual factors in the United States and their association with sexual concurrency could contribute to the nation's profound racial disparities in HIV infection. Copyright © 2013 Elsevier Inc. All rights reserved.

  1. Genetically significant dose and sex ratio of the offsprings of patient treated with 131I for hyperthyroidism

    International Nuclear Information System (INIS)

    Takeshita, Akihisa

    1975-01-01

    The gonadal doses following the 131 I treatment of 6 male and 14 female patients with hyperthyroidism were calculated by the method of MIRD, measuring daily radioactivity in the thyroid gland and circulating blood. The testicular dose was 0.52 +- 0.256 rads and the ovarian dose was 0.632 +- 0.488 rads per mCi. In 1965, the genetically significant dose from 131 I treatment of 925 patients with hyperthyroidism was estimated to be 0.0136 mrads/person/year. The genetically significant dose would amount to 0.0613 mrads/person/year, assuming that the total amount of 131 I supplied for treatment in 1965 was administered to treat the hyperthyroid patients with an age-and sex distribution similar to that of the above mentioned group of patients. Sex ratios of the offspring of male and female patients treated with 131 I from 1953 to 1966 were compared with those of offspring born to male and female patients before the treatment. The proportion of males was higher among the offspring of male patients after 131 I treatment than among the offspring of the controls, but the difference was not statistically significant. The sex ratio of the offspring of female patients was not different from that of controls. The mean age of the parents at the times of their children's birth after 131 I treatment was 2.6 - 6.0 year older in male patients and 2.8 - 2.9 year older in female patients than that of controls. (J.P.N.)

  2. The Effects of Sex-Ratio and Density on Locomotor Activity in the House Fly, Musca domestica

    Science.gov (United States)

    Bahrndorff, Simon; Kjærsgaard, Anders; Pertoldi, Cino; Loeschcke, Volker; Schou, Toke M.; Skovgård, Henrik; Hald, Birthe

    2012-01-01

    Although locomotor activity is involved in almost all behavioral traits, there is a lack of knowledge on what factors affect it. This study examined the effects of sex—ratio and density on the circadian rhythm of locomotor activity of adult Musca domestica L. (Diptera: Muscidae) using an infra—red light system. Sex—ratio significantly affected locomotor activity, increasing with the percentage of males in the vials. In accordance with other studies, males were more active than females, but the circadian rhythm of the two sexes was not constant over time and changed during the light period. There was also an effect of density on locomotor activity, where males at intermediate densities showed higher activity. Further, the predictability of the locomotor activity, estimated as the degree of autocorrelation of the activity data, increased with the number of males present in the vials both with and without the presence of females. Overall, this study demonstrates that locomotor activity in M. domestica is affected by sex—ratio and density. Furthermore, the predictability of locomotor activity is affected by both sex—ratio, density, and circadian rhythm. These results add to our understanding of the behavioral interactions between houseflies and highlight the importance of these factors when designing behavioral experiments using M. domestica.

  3. Testosterone has a long-term effect on primary sex ratio of first eggs in pigeons-in search of a mechanism

    NARCIS (Netherlands)

    Goerlich, V. C.; Dijkstra, C.; Schaafsma, S. M.; Groothuis, T. G. G.

    2009-01-01

    Despite accumulating evidence that birds, in which females are the heterogametic sex, are able to manipulate primary offspring sex ratio, the underlying mechanism remains elusive. Steroid hormones. which govern female reproduction and are also accumulated by the developing follicle could potentially

  4. First Assessment of the Sex Ratio for an East Pacific Green Sea Turtle Foraging Aggregation: Validation and Application of a Testosterone ELISA.

    Directory of Open Access Journals (Sweden)

    Camryn D Allen

    Full Text Available Determining sex ratios of endangered populations is important for wildlife management, particularly species subject to sex-specific threats or that exhibit temperature-dependent sex determination. Sea turtle sex is determined by incubation temperature and individuals lack external sex-based traits until sexual maturity. Previous research utilized serum/plasma testosterone radioimmunoassays (RIA to determine sex in immature/juvenile sea turtles. However, there has been a growing application of enzyme-linked immunosorbent assay (ELISA for wildlife endocrinology studies, but no study on sea turtles has compared the results of ELISA and RIA. This study provides the first sex ratio for a threatened East Pacific green sea turtle (Chelonia mydas foraging aggregation, a critical step for future management of this species. Here, we validate a testosterone ELISA and compare results between RIA and ELISA of duplicate samples. The ELISA demonstrated excellent correspondence with the RIA for providing testosterone concentrations for sex determination. Neither assay proved reliable for predicting the sex of reproductively active females with increased testosterone production. We then applied ELISA to examine the sex ratio of 69 green turtles foraging in San Diego Bay, California. Of 45 immature turtles sampled, sex could not be determined for three turtles because testosterone concentrations fell between the ranges for either sex (females: 4.1-113.1 pg/mL, males: 198.4-2,613.0 pg/mL and these turtles were not subsequently recaptured to enable sex determination; using a Bayesian model to predict probabilities of turtle sex we predicted all three 'unknowns' were female (> 0.86. Additionally, the model assigned all turtles with their correct sex (if determined at recapture with 100% accuracy. Results indicated a female bias (2.83F:1M among all turtles in the aggregation; when focusing only on putative immature turtles the sex ratio was 3.5F:1M. With appropriate

  5. The chromosomal distribution of microsatellite repeats in the genome of the wolf fish Hoplias malabaricus, focusing on the sex chromosomes

    Czech Academy of Sciences Publication Activity Database

    Cioffi, M.B.; Kejnovský, Eduard; Bertollo, L.A.C.

    2011-01-01

    Roč. 132, č. 4 (2011), s. 289-296 ISSN 1424-8581 R&D Projects: GA ČR(CZ) GAP305/10/0930 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : fish sex chromosomes * fluorescence in situ hybridization * microsatellites Subject RIV: BO - Biophysics Impact factor: 1.533, year: 2011

  6. SECULAR TRENDS AND LATITUDE GRADIENTS IN SEX RATIOS AT BIRTH IN THE FORMER SOVIET REPUBLICS

    Directory of Open Access Journals (Sweden)

    Victor Grech

    2013-01-01

    Full Text Available Background: The male-female ratio at birth (M/F: male births divided by total births, which is anticipated to approximate 0.515, has been shown to exhibit latitude gradients and secular trends. Methods: Annual national data for male and female live births for the 15 countries that comprise the former Soviet Union were obtained from the World Health Organisation for the period 1980–2009 (115,167,569 total live births and analysed with contingency tables. Spearman correlation was also carried out to compare percentage annual gross domestic product growth (GDP% – downloaded from the World Bank and M/F. In this context, GDP% is used as a measure for economic hardship or wellbeing within the populace. Results: There have been overall highly significant secular increases in M/F (p < 0.0001 in the countries and regions investigated. M/F is significantly lower in the three more northern regions (Russian Federation, Baltic States and Central Asia. M/F 0.51324, 0.51335-0.51314 than the two more southern regions (Southern Caucasus and Eastern Europe. M/F 0.51654, 0.51635-0.51672. There was a male excess of 113,818 live births.There was a significant positive correlation between GDP% and M/F for Armenia, Azerbaijan and Uzbekistan. There was a significant negative correlation in Estonia. Conclusion: Previous studies have shown that improving socioeconomic conditions increase M/F, and the converse has also been demonstrated. This is a potential influence in this geographical area since this region has relatively recently emerged from communist rule and experienced an overall economic upturn, but is only partially supported using GDP%. Another factor may be the selective termination of female pregnancies. The latitude gradient parallels that of neighbouring Europe but no theory has been put forward to convincingly explain this finding to date.

  7. Positive selection of deleterious alleles through interaction with a sex-ratio suppressor gene in African Buffalo: a plausible new mechanism for a high frequency anomaly.

    Directory of Open Access Journals (Sweden)

    Pim van Hooft

    Full Text Available Although generally rare, deleterious alleles can become common through genetic drift, hitchhiking or reductions in selective constraints. Here we present a possible new mechanism that explains the attainment of high frequencies of deleterious alleles in the African buffalo (Syncerus caffer population of Kruger National Park, through positive selection of these alleles that is ultimately driven by a sex-ratio suppressor. We have previously shown that one in four Kruger buffalo has a Y-chromosome profile that, despite being associated with low body condition, appears to impart a relative reproductive advantage, and which is stably maintained through a sex-ratio suppressor. Apparently, this sex-ratio suppressor prevents fertility reduction that generally accompanies sex-ratio distortion. We hypothesize that this body-condition-associated reproductive advantage increases the fitness of alleles that negatively affect male body condition, causing genome-wide positive selection of these alleles. To investigate this we genotyped 459 buffalo using 17 autosomal microsatellites. By correlating heterozygosity with body condition (heterozygosity-fitness correlations, we found that most microsatellites were associated with one of two gene types: one with elevated frequencies of deleterious alleles that have a negative effect on body condition, irrespective of sex; the other with elevated frequencies of sexually antagonistic alleles that are negative for male body condition but positive for female body condition. Positive selection and a direct association with a Y-chromosomal sex-ratio suppressor are indicated, respectively, by allele clines and by relatively high numbers of homozygous deleterious alleles among sex-ratio suppressor carriers. This study, which employs novel statistical techniques to analyse heterozygosity-fitness correlations, is the first to demonstrate the abundance of sexually-antagonistic genes in a natural mammal population. It also has

  8. The effects of sex, sexual orientation, and digit ratio (2D:4D) on mental rotation performance.

    Science.gov (United States)

    Peters, Michael; Manning, John T; Reimers, Stian

    2007-04-01

    In spite of the reduced level of experimental control, this large scale study brought some clarity into the relation between mental rotation task (MRT) performance and a number of variables where contradictory associations had previously been reported in the literature. Clear sex differences in MRT were observed for a sample of 134,317 men and 120,783 women, with men outperforming women. There were also MRT differences as a function of sexual orientation: heterosexual men performed better than homosexual men and homosexual women performed better than heterosexual women. Although bisexual men performed better than homosexual men but less well than heterosexual men, no significant differences were observed between bisexual and homosexual women. MRT performance in both men and women peaked in the 20-30 year range, and declined significantly and markedly thereafter. Both men and women showed a significant negative correlation between left and right digit finger ratio and MRT scores, such that individuals with smaller digit ratios (relatively longer ring finger than index finger) performed better than individuals with larger digit ratios.

  9. Impacts of temperature and crowding on sex ratio, fecundity and Wolbachia infection intensity in the copepod, Mesocyclops thermocyclopoides.

    Science.gov (United States)

    Wiwatanaratanabutr, Itsanun; Grandjean, Frederic

    2016-11-01

    Wolbachia are a group of intracellular bacteria that cause reproductive alterations in arthropods. Here, we describe the effects of two environmental factors (crowding and temperature) on phenotypic expression of feminization, the host's fecundity and Wolbachia infection intensity among life cycle stages in the naturally Wolbachia-infected copepod, Mesocyclops thermocyclopoides. The copepod was first found to be co-infected with Wolbachia A- and B-supergroups Wolbachia strains based on wsp primers. The relative Wolbachia infection intensity within individuals was determined using quantitative real-time PCR and was significantly higher in the B-supergroup than in the A-supergroup. Experimental results of temperature effect on bacterial density in each developmental stage revealed a significant decrease in Wolbachia infection intensity following exposure to high temperature (37°C) in both sexes and implied that Wolbachia might survive in room temperature (25°C) better than in high temperature. Experimental results of crowding effects on Wolbachia infection intensity suggested a negative correlation between copepod nauplii and Wolbachia infection intensity. No effect of rearing temperature on the sex ratio was reported although the fecundity was significantly decreased by high temperature. The results showed that Wolbachia infection intensity to be correlated with crowding conditions and was decreased following exposure of elevated temperature. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Seasonal changes in the gonadossomatic index, allometric condition factor and sex ratio of an auchenipterid catfish from eastern Amazonia

    Directory of Open Access Journals (Sweden)

    Tiago Magalhães da Silva Freitas

    Full Text Available The aim of the present study was to evaluate the seasonal pattern of the gonadosomatic index (GSI, condition factor (K, and sex ratio in the catfish Auchenipterichthys longimanus (Siluriformes: Auchenipteridae as an approach to identify its reproductive period. A total of 589 A. longimanus specimens (251 males and 338 females were captured in the rivers of the Caxiuanã National Forest, in the Brazilian state of Pará, between July, 2008 and July, 2009. Among the male specimens, 171 were classified as adults and 80 as juveniles, while there were 249 adults and 89 juvenile females. Using a sinusoidal equation, analysis of the GSI revealed a reproductive asynchrony between the genders, with males attaining their highest GSI values in January, while females peaked in March. For males, the sinusoidal regression for GSI values was significant only when used the complete data set (P=0.001, wears no trend was identified for bimonthly means (P=0.136. For females, by contrast, significant values were obtained for both the complete data set (P=0.012 and bimonthly GSI means (P=0.026. For the condition factor, the sinusoidal equation returned significant seasonal variation in both raw data (P=0.02 and with mean values (P=0.00 for males, but only with raw data for females (P=0.04, which appears to reflect variation in the energy budget between genders. With regard to the sex ratio, more reproductive females were captured than males in January and March, 2009, which suggests a pattern of segregation related to the reproductive process. These parameters are fundamental to the assessment, protection, and management of natural fish stocks, as well as providing guidelines for the development of conservation strategies.

  11. Low reproductive skew despite high male-biased operational sex ratio in a glass frog with paternal care.

    Science.gov (United States)

    Mangold, Alexandra; Trenkwalder, Katharina; Ringler, Max; Hödl, Walter; Ringler, Eva

    2015-09-03

    Reproductive skew, the uneven distribution of reproductive success among individuals, is a common feature of many animal populations. Several scenarios have been proposed to favour either high or low levels of reproductive skew. Particularly a male-biased operational sex ratio and the asynchronous arrival of females is expected to cause high variation in reproductive success among males. Recently it has been suggested that the type of benefits provided by males (fixed vs. dilutable) could also strongly impact individual mating patterns, and thereby affecting reproductive skew. We tested this hypothesis in Hyalinobatrachium valerioi, a Neotropical glass frog with prolonged breeding and paternal care. We monitored and genetically sampled a natural population in southwestern Costa Rica during the breeding season in 2012 and performed parentage analysis of adult frogs and tadpoles to investigate individual mating frequencies, possible mating preferences, and estimate reproductive skew in males and females. We identified a polygamous mating system, where high proportions of males (69 %) and females (94 %) reproduced successfully. The variance in male mating success could largely be attributed to differences in time spent calling at the reproductive site, but not to body size or relatedness. Female H. valerioi were not choosy and mated indiscriminately with available males. Our findings support the hypothesis that dilutable male benefits - such as parental care - can favour female polyandry and maintain low levels of reproductive skew among males within a population, even in the presence of direct male-male competition and a highly male-biased operational sex ratio. We hypothesize that low male reproductive skew might be a general characteristic in prolonged breeders with paternal care.

  12. Experimentally manipulated brood sex ratios : Growth and survival in the black-headed gull (Larus ridibundus), a sexually dimorphic species

    NARCIS (Netherlands)

    Mueller, Wendt; Kalmbach, E; Eising, C.M; Groothuis, TGG; Dijkstra, C

    2005-01-01

    In sexually size dimorphic species, individuals of the larger sex often suffer from enhanced mortality during the nestling period. This has been attributed to higher nutritional requirements of the larger sex, which may render this sex more vulnerable to adverse food conditions. However, sex-biased

  13. Parallel distribution of sexes within left and right uterine horns in Holstein dairy cows: evidence that the effect of side of pregnancy on sex ratio could be breed-specific in cattle.

    Science.gov (United States)

    Gharagozlou, F; Vojgani, M; Akbarinejad, V; Niasari-Naslaji, A; Hemmati, M; Youssefi, R

    2013-11-30

    Dissimilar distribution of male and female calves within left and right uterine horns has been observed in beef cows. A retrospective study was conducted to investigate the effect of side of pregnancy on secondary sex ratio in Holstein dairy cows. Data associated with sex of calves, side of pregnancy, sire, dam, parity number of dam, AI technician, season and year were retrieved from the database of a Holstein dairy farm. In total, data consisted of 6515 birth records from 3155 dams and 244 sires across years 2001-2010. Data were analyzed using logistic regression. There was no difference in proportion of male and female calves between left (52.9% and 47.1%, respectively) and right (53.2% and 46.8%, respectively) uterine horns (P>0.05). AI technician, year, season and parity of dam did not affect secondary sex ratio (P>0.05). Secondary sex ratio of left and right uterine horns, and consequently, overall secondary sex ratio (53.1%) were skewed toward males as compared with hypothetical secondary sex ratio of 50% (Pcows. Copyright © 2013 Elsevier B.V. All rights reserved.

  14. Reproductive and behavioral aspects of red-winged tinamous (Rhynchotus rufescens in groups with different sex ratios

    Directory of Open Access Journals (Sweden)

    VU Cromberg

    2007-09-01

    Full Text Available The aim of this research study was to evaluate the reproductive performance of tinamous submitted to five different male:female ratios. The study was carried out with 72 birds in a randomized experimental design with 4 replications. Tinamous were housed in cages, using the ratios of one (1:1, two (2:1, three (3:1 and four (4:1 females per male, and also one male was housed with three females individually (3R:1, in a rotational system. Reproductive records of the breeding season from September 2004 to March 2005 were used. The reproductive traits studied were: number of eggs laid, fertility, and percentage of eggs damaged and cracked by pecking. Nonparametric analyses of these traits were performed using Kruskal-Wallis test. Two replications of treatments 1:1 and 4:1, and one of treatment 2:1 were video-taped for three days, 12 hours/day. The videotapes were sampled according to the scan method to fit an ethogram. Birds were also watched for one hour per day to study dominance and agonistic behavior. None of the reproductive traits was affected by mating sex ratio (p<0.05. Female dominance could be related to displacement behavior (r=1.00, and male sitting in immobility plus sitting in activity behaviors were related to lower number of damaged eggs (r=-0.90. Social dominance was indirectly determined by displacement behavior in the study situation. A large number of damaged eggs occurred in all treatments, thereby not allowing a clear conclusion on the best male:female ratio.

  15. In patients suffering from idiopathic central serous chorioretinopathy, anxiety scores are higher than in healthy controls, but do not vary according to sex or repeated central serous chorioretinopathy.

    Science.gov (United States)

    Bazzazi, Nooshin; Ahmadpanah, Mohammad; Akbarzadeh, Siamak; Seif Rabiei, Mohammad Ali; Holsboer-Trachsler, Edith; Brand, Serge

    2015-01-01

    Idiopathic central serous chorioretinopathy (CSCR) is a relatively common ophthalmic disorder characterized by the development of a serous detachment of the sensory retina. Psychophysiological factors may trigger or maintain CSCR, though, surprisingly, the association between CSCR and anxiety has yet to be studied. The aims of the present study were threefold: to determine whether 1) Iranian patients with CSCR have higher scores for anxiety, 2) anxiety is lower, if CSCR has been experienced twice, and whether 3) anxiety scores differ between sexes. A total of 30 patients with CSCR and 30 healthy age-and sex-matched controls took part in the study. A brief face-to-face interview was conducted covering demographic variables and history and occurrence of CSCR and assessing anxiety. Compared to healthy controls, anxiety was significantly higher in both first-time and second-time CSCR patients. In CSCR patients, anxiety scores did not differ between sexes. Higher anxiety scores were observed in Iranian patients with CSCR, irrespective of whether this was the first or second occurrence of CSCR. This suggests there is no psychological adaptation in terms of reduced anxiety among patients with repeated CSCR.

  16. Normal Female Germ Cell Differentiation Requires the Female X Chromosome to Autosome Ratio and Expression of Sex-Lethal in DROSOPHILA MELANOGASTER

    OpenAIRE

    Schüpbach, Trudi

    1985-01-01

    In somatic cells of Drosophila, the ratio of X chromosomes to autosomes (X:A ratio) determines sex and dosage compensation. The present paper addresses the question of whether germ cells also use the X:A ratio for sex determination and dosage compensation. Triploid female embryos were generated which, through the loss of an unstable ring-X chromosome, contained some germ cells of 2X;3A constitution in their ovaries. Such germ cells were shown to differentiate along one of two alternative pat...

  17. Sex ratio of offspring and occupational exposure to fly ash : a historical cohort study of municipal solid waste incinerator workers in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Mori, I.; Ogawa, Y. [National Inst. of Industrial Health, Tokyo (Japan); Kumagai, S. [Osaka Prefectural Inst. of Public Health, Osaka (Japan); Koda, S. [Kochi Medical School, Nangoku (Japan); Ueno, M. [All-Japan Prefectural and Municipal Workers Union, Tokyo (Japan)

    2005-07-01

    This paper described a cohort study which focused on risk assessment for cancer mortality and changes in the sex ratio of offspring among municipal solid waste incinerator (MSWI) workers in Japan. A baseline survey was conducted by survey with both MSWI workers as well as a reference population of waste collection workers. Questions were related to offspring, job history, and frequency of exposure to fly ash during incinerator work. A total of 5211 records were then analyzed as well as 10,571 children. Duration of exposure to fly ash was used as a surrogate exposure index. Results showed that longer exposure to fly ash influenced the sex ratio. Results of a multivariate analysis conducted to compute the odds ratio of female birth by different exposure indices were similar to results obtained in a univariate analysis. It was concluded that an association between duration of exposure to fly ash and changes in sex ratio was determined. 5 refs., 3 tabs.

  18. Live birth sex ratio after in vitro fertilization and embryo transfer in China--an analysis of 121,247 babies from 18 centers.

    Science.gov (United States)

    Bu, Zhiqin; Chen, Zi-Jiang; Huang, Guoning; Zhang, Hanwang; Wu, Qiongfang; Ma, Yanping; Shi, Juanzi; Xu, Yanwen; Zhang, Songying; Zhang, Cuilian; Zhao, Xiaoming; Zhang, Bo; Huang, Yuanhua; Sun, Zhengyi; Kang, Yuefan; Wu, Riran; Wu, Xueqing; Sun, Haixiang; Sun, Yingpu

    2014-01-01

    In order to study the impact of procedures of IVF/ICSI technology on sex ratio in China, we conducted this multi-center retrospective study including 121,247 babies born to 93,895 women in China. There were 62,700 male babies and 58,477 female babies, making the sex ratio being 51.8% (Male: Female  = 107:100). In univariate logistic regression analysis, sex ratio was imbalance toward females of 50.3% when ICSI was preformed compared to 47.7% when IVF was used (Pratio in IVF/ICSI babies was significantly higher toward males in transfers of blastocyst (54.9%) and thawed embryo (52.4%) when compared with transfers of cleavage stage embryo (51.4%) and fresh embryo (51.5%), respectively. Multiple delivery was not associated with sex ratio. However, in multivariable logistic regression analysis after controlling for related factors, only ICSI (adjusted OR =  .90, 95%CI: 0.88-0.93; Pratio in IVF/ICSI babies. In conclusion, the live birth sex ratio in IVF/ICSI babies was influenced by the use of ICSI, which may decrease the percentage of male offspring, or the use of blastocyst transfer, which may increase the percentage of male offspring.

  19. Genome-wide association study uncovers a novel QTL allele of AtS40-3 that affects the sex ratio of cyst nematodes in Arabidopsis.

    Science.gov (United States)

    Anwer, Muhammad Arslan; Anjam, Muhammad Shahzad; Shah, Syed Jehangir; Hasan, M Shamim; Naz, Ali A; Grundler, Florian M W; Siddique, Shahid

    2018-03-24

    Plant-parasitic cyst nematodes are obligate sedentary parasites that infect the roots of a broad range of host plants. Cyst nematodes are sexually dimorphic, but differentiation into male or female is strongly influenced by interactions with the host environment. Female populations typically predominate under favorable conditions, whereas male populations predominate under adverse conditions. Here, we performed a genome-wide association study (GWAS) in an Arabidopsis diversity panel to identify host loci underlying variation in susceptibility to cyst nematode infection. Three different susceptibility parameters were examined, with the aim of providing insights into the infection process, the number of females and males present in the infected plant, and the female-to-male sex ratio. GWAS results suggested that variation in sex ratio is associated with a novel quantitative trait locus allele on chromosome 4. Subsequent candidate genes and functional analyses revealed that a senescence-associated transcription factor, AtS40-3, and PPR may act in combination to influence nematode sex ratio. A detailed molecular characterization revealed that variation in nematode sex ratio was due to the disturbed common promoter of AtS40-3 and PPR genes. Additionally, single nucleotide polymorphisms in the coding sequence of AtS40-3 might contribute to the natural variation in nematode sex ratio.

  20. Birth order, sibling sex ratio, handedness, and sexual orientation of male and female participants in a BBC internet research project.

    Science.gov (United States)

    Blanchard, Ray; Lippa, Richard A

    2007-04-01

    This study investigated the relations among sexual orientation, fraternal birth order (number of older brothers), and hand-preference. The participants were 87,798 men and 71,981 women who took part in a Web-based research project sponsored by the British Broadcasting Corporation (BBC). The results yielded some evidence confirming prior findings that non-right-handedness is associated with homosexuality in men and women, that older brothers increase the odds of homosexuality in men, and that the effect of older brothers on sexual orientation is limited to right-handed men. The evidence was weaker than in previous studies, however, probably because the usual relations among the variables of interest were partially obscured by the effects of other factors. Thus, the homosexual men and women had higher rates of non-right-handedness than their heterosexual counterparts, but the strongest handedness finding for both sexes was a marked tendency for participants who described themselves as ambidextrous also to describe themselves as bisexual. The birth order data were strongly affected by a tendency for the male participants to report an excess of older sisters, and the female participants to report an excess of older brothers. Statistical analyses confirmed that this was an artifact of the parental stopping rule, "Continue having children until you have offspring of both sexes." In subsequent analyses, participants were divided into those who did and did not have younger siblings, on the grounds that the data of the former would be less contaminated by the stopping rule. In the former subsample, the right-handed homo/bisexual males showed the typical high ratio of older brothers to older sisters, whereas the non-right-handed homo/bisexual males did not.

  1. Effect of estradiol-17β on the sex ratio, growth and survival of juvenile common snook (Centropomus undecimalis)

    OpenAIRE

    Cristina Vaz Avelar de Carvalho; Gabriel Passini; Wanessa de Melo Costa; Beatriz Nunes Vieira; Vinicius Ronzani Cerqueira

    2014-01-01

    Sex control in fish is a promising technique for aquaculture, since it gives advantages associated with one sex. The aim of this study was to investigate the feminization of common snook (Centropomus undecimalis) by oral administration of two doses of estradiol-17β (50 and 100 mg E2 kg-1 feed) and control treatment for 45 days and to evaluate their effects on the sex ratio, growth and survival of common snook juveniles. After this period, fish were fed only with commercial feed without hormon...

  2. Repeated exposure to methamphetamine induces sex-dependent hypersensitivity to ischemic injury in the adult rat heart.

    Directory of Open Access Journals (Sweden)

    Boyd R Rorabaugh

    Full Text Available We previously reported that adult female, but not male rats that were prenatally exposed to methamphetamine exhibit myocardial hypersensitivity to ischemic injury. However, it is unknown whether hypersensitivity to ischemic injury develops when rats are exposed to methamphetamine during adulthood. The goal of this study was to determine whether methamphetamine exposure during adulthood sensitizes the heart to ischemic injury.Adult male and female rats received daily injections of methamphetamine (5 mg/kg or saline for 10 days. Their hearts were isolated on day 11 and subjected to a 20 min ischemic insult on a Langendorff isolated heart apparatus. Cardiac contractile function was measured by an intraventricular balloon, and infarct size was measured by triphenyltetrazolium chloride staining.Hearts from methamphetamine-treated females exhibited significantly larger infarcts and suppressed postischemic recovery of contractile function compared to hearts from saline-treated females. In contrast, methamphetamine had no effect on infarct size or contractile recovery in male hearts. Subsequent experiments demonstrated that hypersensitivity to ischemic injury persisted in female hearts following a 1 month period of abstinence from methamphetamine. Myocardial protein kinase C-ε expression, Akt phosphorylation, and ERK phosphorylation were unaffected by adult exposure to methamphetamine.Exposure of adult rats to methamphetamine sex-dependently increases the extent of myocardial injury following an ischemic insult. These data suggest that women who have a heart attack might be at risk of more extensive myocardial injury if they have a recent history of methamphetamine abuse.

  3. Repeated exposure to methamphetamine induces sex-dependent hypersensitivity to ischemic injury in the adult rat heart

    Science.gov (United States)

    Seeley, Sarah L.; Stoops, Thorne S.; D’Souza, Manoranjan S.

    2017-01-01

    Background We previously reported that adult female, but not male rats that were prenatally exposed to methamphetamine exhibit myocardial hypersensitivity to ischemic injury. However, it is unknown whether hypersensitivity to ischemic injury develops when rats are exposed to methamphetamine during adulthood. The goal of this study was to determine whether methamphetamine exposure during adulthood sensitizes the heart to ischemic injury. Methods Adult male and female rats received daily injections of methamphetamine (5 mg/kg) or saline for 10 days. Their hearts were isolated on day 11 and subjected to a 20 min ischemic insult on a Langendorff isolated heart apparatus. Cardiac contractile function was measured by an intraventricular balloon, and infarct size was measured by triphenyltetrazolium chloride staining. Results Hearts from methamphetamine-treated females exhibited significantly larger infarcts and suppressed postischemic recovery of contractile function compared to hearts from saline-treated females. In contrast, methamphetamine had no effect on infarct size or contractile recovery in male hearts. Subsequent experiments demonstrated that hypersensitivity to ischemic injury persisted in female hearts following a 1 month period of abstinence from methamphetamine. Myocardial protein kinase C-ε expression, Akt phosphorylation, and ERK phosphorylation were unaffected by adult exposure to methamphetamine. Conclusions Exposure of adult rats to methamphetamine sex-dependently increases the extent of myocardial injury following an ischemic insult. These data suggest that women who have a heart attack might be at risk of more extensive myocardial injury if they have a recent history of methamphetamine abuse. PMID:28575091

  4. Breeding of Djungarian hamsters (Phodopus sungorus): influence of parity and litter size on weaning success and offspring sex ratio.

    Science.gov (United States)

    Lerchl, A

    1995-04-01

    The reproduction of 368 breeding pairs of Djungarian hamsters (Phodopus sungorus) has been recorded and evaluated during 5 consecutive years. Three-hundred-and-eight pairs (= 83.7%) were successful breeders giving birth to 2113 litters (up to 13 per dam) with a total of 12,591 offspring (mean: 6.0 +/- 2.2 [+/- SD] per litter). One-hundred-and-fifty dams delivered within 25 days after pairing, indicating a breeding success in the first oestrous cycle of 40.8% of all pairs (95% confidence interval: 35.7%-46.0%). The average number of offspring was higher in the 2nd than in the first litter, reaching a maximum in the 3rd (6.8 +/- 2.0), and decreasing thereafter. The loss of offspring (mean: 24.2%) was higher in older parents and influenced by the number of offspring per litter, indicating that experience and stress contribute to breeding success. A small, but significantly higher number of females was recorded only when no loss of offspring occurred until weaning (females: 2.36 +/- 1.75; males: 2.16 +/- 1.63, P sex ratio towards favouring females with increased litter numbers, in contrast to the predictions of the Trivers-Willard hypothesis, at least with respect to the species and the breeding conditions as described in this report. Since all breeders were kept under long-day type photoperiods (16L:8D), no signs of seasonality in breeding outcome were noted.

  5. Molecular signature of epistatic selection: interrogating genetic interactions in the sex-ratio meiotic drive of Drosophila simulans.

    Science.gov (United States)

    Chevin, Luis-Miguel; Bastide, Héloïse; Montchamp-Moreau, Catherine; Hospital, Frédéric

    2009-06-01

    Fine scale analyses of signatures of selection allow assessing quantitative aspects of a species' evolutionary genetic history, such as the strength of selection on genes. When several selected loci lie in the same genomic region, their epistatic interactions may also be investigated. Here, we study how the neutral polymorphism pattern was shaped by two close recombining loci that cause 'sex-ratio' meiotic drive in Drosophila simulans, as an example of strong selection with potentially strong epistasis. We compare the polymorphism data observed in a natural population with the results of forward stochastic simulations under several contexts of epistasis between the candidate loci for the drive. We compute the likelihood of different possible scenarios, in order to determine which configuration is most consistent with the data. Our results highlight that fine scale analyses of well-chosen candidate genomic regions provide information-rich data that can be used to investigate the genotype-phenotype-fitness map, which can hardly be studied in genome-wide analyses. We also emphasize that initial conditions and time of observation (here, time after the interruption of a partial selective sweep) are crucial parameters in the interpretation of real data, while these are often overlooked in theoretical studies.

  6. In patients suffering from idiopathic central serous chorioretinopathy, anxiety scores are higher than in healthy controls, but do not vary according to sex or repeated central serous chorioretinopathy

    Directory of Open Access Journals (Sweden)

    Bazzazi N

    2015-04-01

    Full Text Available Nooshin Bazzazi,1 Mohammad Ahmadpanah,2 Siamak Akbarzadeh,1 Mohammad Ali Seif Rabiei,3 Edith Holsboer-Trachsler,4 Serge Brand4,5 1Department of Ophthalmology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; 2Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences; Hamadan, Iran; 3Department of Social Medicine, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; 4Psychiatric Clinics of the University of Basel, Center for Affective, Stress and Sleep Disorders, Basel, Switzerland; 5Department of Sport and Health Science, Sport Science Section, University of Basel, Basel, Switzerland Introduction: Idiopathic central serous chorioretinopathy (CSCR is a relatively common ophthalmic disorder characterized by the development of a serous detachment of the sensory retina. Psychophysiological factors may trigger or maintain CSCR, though, surprisingly, the association between CSCR and anxiety has yet to be studied. The aims of the present study were threefold: to determine whether 1 Iranian patients with CSCR have higher scores for anxiety, 2 anxiety is lower, if CSCR has been experienced twice, and whether 3 anxiety scores differ between sexes.Methods: A total of 30 patients with CSCR and 30 healthy age- and sex-matched controls took part in the study. A brief face-to-face interview was conducted covering demographic variables and history and occurrence of CSCR and assessing anxiety.Results: Compared to healthy controls, anxiety was significantly higher in both first-time and second-time CSCR patients. In CSCR patients, anxiety scores did not differ between sexes.Conclusion: Higher anxiety scores were observed in Iranian patients with CSCR, irrespective of whether this was the first or second occurrence of CSCR. This suggests there is no psychological adaptation in terms of reduced anxiety among patients with repeated CSCR. Keywords: idiopathic central

  7. Maternal fructose and/or salt intake and reproductive outcome in the rat: effects on growth, fertility, sex ratio, and birth order.

    Science.gov (United States)

    Gray, Clint; Long, Sophie; Green, Charlotte; Gardiner, Sheila M; Craigon, Jim; Gardner, David S

    2013-09-01

    Maternal diet can significantly skew the secondary sex ratio away from the expected value of 0.5 (proportion males), but the details of how diet may do this are unclear. Here, we altered dietary levels of salt (4% salt in the feed) and/or fructose (10% in the drinking water) of pregnant rats to model potential effects that consumption of a "Western diet" might have on maternofetal growth, development, and sex ratio. We demonstrate that excess fructose consumption before and during pregnancy lead to a marked skew in the secondary sex ratio (proportion of males, 0.60; P < 0.006). The effect was not mediated by selective developmental arrest of female embryos or influenced by fetal position in the uterine horn or sex-specific effects on sperm motility, suggesting a direct effect of glycolyzable monosaccharide on the maternal ovary and/or ovulated oocyte. Furthermore, combined excess maternal consumption of salt and fructose-sweetened beverage significantly reduced fertility, reflected as a 50% reduction in preimplantation and term litter size. In addition, we also noted birth order effects in the rat, with sequential implantation sites tending to be occupied by the same sex.

  8. Genetic Diversity of the Invasive Gall Wasp Leptocybe invasa (Hymenoptera: Eulophidae and of its Rickettsia Endosymbiont, and Associated Sex-Ratio Differences.

    Directory of Open Access Journals (Sweden)

    Francesco Nugnes

    Full Text Available The blue-gum chalcid Leptocybe invasa Fisher & LaSalle (Hymenoptera: Eulophidae is a gall wasp pest of Eucalyptus species, likely native to Australia. Over the past 15 years it has invaded 39 countries on all continents where eucalypts are grown. The worldwide invasion of the blue gum chalcid was attributed to a single thelytokous morphospecies formally described in 2004. Subsequently, however, males have been recorded in several countries and the sex ratio of field populations has been found to be highly variable in different areas. In order to find an explanation for such sex ratio differences, populations of L. invasa from a broad geographical area were screened for the symbionts currently known as reproductive manipulators, and both wasps and symbionts were genetically characterized using multiple genes. Molecular analyses suggested that L. invasa is in fact a complex of two cryptic species involved in the rapid and efficient spread of the wasp, the first recovered from the Mediterranean region and South America, the latter from China. All screened specimens were infected by endosymbiotic bacteria belonging to the genus Rickettsia. Two closely related Rickettsia strains were found, each infecting one of the two putative cryptic species of L. invasa and associated with different average sex ratios. Rickettsia were found to be localized in the female reproductive tissues and transovarially transmitted, suggesting a possible role of Rickettsia as the causal agent of thelytokous parthenogenesis in L. invasa. Implications for the variation of sex ratio and for the management of L. invasa are discussed.

  9. Genetic Diversity of the Invasive Gall Wasp Leptocybe invasa (Hymenoptera: Eulophidae) and of its Rickettsia Endosymbiont, and Associated Sex-Ratio Differences

    Science.gov (United States)

    Nugnes, Francesco; Gebiola, Marco; Monti, Maurilia Maria; Gualtieri, Liberata; Giorgini, Massimo; Wang, Jianguo; Bernardo, Umberto

    2015-01-01

    The blue-gum chalcid Leptocybe invasa Fisher & LaSalle (Hymenoptera: Eulophidae) is a gall wasp pest of Eucalyptus species, likely native to Australia. Over the past 15 years it has invaded 39 countries on all continents where eucalypts are grown. The worldwide invasion of the blue gum chalcid was attributed to a single thelytokous morphospecies formally described in 2004. Subsequently, however, males have been recorded in several countries and the sex ratio of field populations has been found to be highly variable in different areas. In order to find an explanation for such sex ratio differences, populations of L. invasa from a broad geographical area were screened for the symbionts currently known as reproductive manipulators, and both wasps and symbionts were genetically characterized using multiple genes. Molecular analyses suggested that L. invasa is in fact a complex of two cryptic species involved in the rapid and efficient spread of the wasp, the first recovered from the Mediterranean region and South America, the latter from China. All screened specimens were infected by endosymbiotic bacteria belonging to the genus Rickettsia. Two closely related Rickettsia strains were found, each infecting one of the two putative cryptic species of L. invasa and associated with different average sex ratios. Rickettsia were found to be localized in the female reproductive tissues and transovarially transmitted, suggesting a possible role of Rickettsia as the causal agent of thelytokous parthenogenesis in L. invasa. Implications for the variation of sex ratio and for the management of L. invasa are discussed. PMID:25970681

  10. Are environmental factors responsible for geographic variation in the sex ratio of the Greenlandic seed-bug Nysius groenlandicus?

    DEFF Research Database (Denmark)

    Bøcher, Jens Jensenius; Nachman, Gøsta Støger

    2010-01-01

    Until recently nothing indicated an unequal sex ratio in the widespread Greenland seed-bug Nysius groenlandicus (Zetterstedt) (Heteroptera: Lygaeidae). However, recently populations more or less devoid of males were discovered in high arctic Northeast Greenland. This initiated an inspection of th...

  11. Birth Order and Sibling Sex Ratio in a Population with High Fertility: Are Turkish Male to Female Transsexuals Different?

    Science.gov (United States)

    Bozkurt, Ali; Bozkurt, Ozlem Hekim; Sonmez, Ipek

    2015-07-01

    Western studies have consistently found that androphilic (sexually attracted to men) male-to-female transsexuals have a later birth order and a relative excess of brothers compared with appropriate control participants. However, non-Western studies on birth order and sibling sex ratio in androphilic males (transsexual or non-transsexual) are rare. The objective of the study was to test the hypothesis that androphilic male-to-female transsexuals have a late birth order and a relative excess of brothers in a non-Western culture with a higher fertility rate. The participants were 60 androphilic male-to-female transsexuals and 61 male heterosexual controls. The transsexual participants had significantly more older brothers than the control participants, but the groups did not differ in their numbers of older sisters, younger brothers, or younger sisters. The foregoing pattern is usually referred to as the "fraternal birth order effect." Slater's and Berglin's Indexes both showed that the mean birth order of the control participants was very close to that expected from a random sample drawn from a demographically stable population whereas the mean birth order of the transsexual participants was later. A measure of sibship composition, brothers/all siblings, showed that the transsexual group had a higher proportion of male siblings compared with the control group. In conclusion, the present study found that Turkish androphilic male-to-female transsexuals show the same high fraternal birth order that has been found in comparable androphilic samples in Western Europe, North America, and the South Pacific, which suggests a common underlying biological causal mechanism.

  12. Sex-specific effects of altered competition on nestling growth and survival : an experimental manipulation of brood size and sex ratio

    NARCIS (Netherlands)

    Nicolaus, Marion; Michler, Stephanie P. M.; Ubels, Richard; van der Velde, Marco; Komdeur, Jan; Both, Christiaan; Tinbergen, Joost M.; Wright, Jonathan

    An increase of competition among adults or nestlings usually negatively affects breeding output. Yet little is known about the differential effects that competition has on the offspring sexes. This could be important because it may influence parental reproductive decisions. In sexual size dimorphic

  13. Determine sex ratios of green turtles along the U.S. West Coast through examinations of hormones

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A testosterone (T) enzyme-linked immunosorbent assay (ELISA) was validated for use with green turtle plasma in order to determine the sex of juvenile turtles. We...

  14. DNA methylation of the gonadal aromatase (cyp19a promoter is involved in temperature-dependent sex ratio shifts in the European sea bass.

    Directory of Open Access Journals (Sweden)

    Laia Navarro-Martín

    2011-12-01

    Full Text Available Sex ratio shifts in response to temperature are common in fish and reptiles. However, the mechanism linking temperature during early development and sex ratios has remained elusive. We show in the European sea bass (sb, a fish in which temperature effects on sex ratios are maximal before the gonads form, that juvenile males have double the DNA methylation levels of females in the promoter of gonadal aromatase (cyp19a, the enzyme that converts androgens into estrogens. Exposure to high temperature increased the cyp19a promoter methylation levels of females, indicating that induced-masculinization involves DNA methylation-mediated control of aromatase gene expression, with an observed inverse relationship between methylation levels and expression. Although different CpGs within the sb cyp19a promoter exhibited different sensitivity to temperature, we show that the increased methylation of the sb cyp19a promoter, which occurs in the gonads but not in the brain, is not a generalized effect of temperature. Importantly, these effects were also observed in sexually undifferentiated fish and were not altered by estrogen treatment. Thus, methylation of the sb cyp19a promoter is the cause of the lower expression of cyp19a in temperature-masculinized fish. In vitro, induced methylation of the sb cyp19a promoter suppressed the ability of SF-1 and Foxl2 to stimulate transcription. Finally, a CpG differentially methylated by temperature and adjacent to a Sox transcription factor binding site is conserved across species. Thus, DNA methylation of the aromatase promoter may be an essential component of the long-sought-after mechanism connecting environmental temperature and sex ratios in vertebrate species with temperature-dependent sex determination.

  15. Seasonal changes in the gonadossomatic index, allometric condition factor and sex ratio of an auchenipterid catfish from eastern Amazonia

    Directory of Open Access Journals (Sweden)

    Tiago Magalhães da Silva Freitas

    2011-01-01

    Full Text Available The aim of the present study was to evaluate the seasonal pattern of the gonadosomatic index (GSI, condition factor (K, and sex ratio in the catfish Auchenipterichthys longimanus (Siluriformes: Auchenipteridae as an approach to identify its reproductive period. A total of 589 A. longimanus specimens (251 males and 338 females were captured in the rivers of the Caxiuanã National Forest, in the Brazilian state of Pará, between July, 2008 and July, 2009. Among the male specimens, 171 were classified as adults and 80 as juveniles, while there were 249 adults and 89 juvenile females. Using a sinusoidal equation, analysis of the GSI revealed a reproductive asynchrony between the genders, with males attaining their highest GSI values in January, while females peaked in March. For males, the sinusoidal regression for GSI values was significant only when used the complete data set (P=0.001, wears no trend was identified for bimonthly means (P=0.136. For females, by contrast, significant values were obtained for both the complete data set (P=0.012 and bimonthly GSI means (P=0.026. For the condition factor, the sinusoidal equation returned significant seasonal variation in both raw data (P=0.02 and with mean values (P=0.00 for males, but only with raw data for females (P=0.04, which appears to reflect variation in the energy budget between genders. With regard to the sex ratio, more reproductive females were captured than males in January and March, 2009, which suggests a pattern of segregation related to the reproductive process. These parameters are fundamental to the assessment, protection, and management of natural fish stocks, as well as providing guidelines for the development of conservation strategies.O objetivo deste estudo foi avaliar alterações sazonais no índice gonadossomático (IGS%, fator de condição (K e proporção sexual, a fim de determinar o período de atividade reprodutiva do bagre Auchenipterichthys longimanus (Siluriformes

  16. Sex differences in college students' free drawings and their relationship to 2D:4D ratio and recalled childhood play behavior.

    Science.gov (United States)

    Rothkopf, Ian; Turgeon, Sarah M

    2014-02-01

    In a prior study, we observed that female-typical characteristics in elementary school girls' drawings were correlated with a feminized digit ratio (2D:4D), a marker for prenatal androgen exposure. However, this observation was limited to older girls, suggesting that social factors mediate the relationship between 2D:4D and drawing. To examine the hypothesis that the influence of prenatal androgen on girls' drawing is mediated by an effect of early androgens on sex-typical behavior, we examined 2D:4D, free drawings, and scores on the Recalled Childhood Gender Identity (RCGI) Questionnaire in a population of college students. Characteristics of participants' free drawings were assessed and those that showed sex differences were compared with 2D:4D and RCGI scores. Men had smaller 2D:4D ratios than women, used fewer total colors, used fewer pinks, purples, and blues, and had higher gender-typical scores on the RCGI. Women's drawings were more likely to contain flowers and animals and men's drawings were more likely to represent sports. Within-sex RCGI and 2D:4D scores were not significantly correlated. Significant within-sex relationships between 2D:4D and RCGI and drawing behavior were observed but the effects appeared to be independent; the hypothesis that gender-typical childhood behavior mediates the effect of prenatal androgen on drawing characteristics was not supported.

  17. Assembling large genomes: analysis of the stick insect (Clitarchus hookeri) genome reveals a high repeat content and sex-biased genes associated with reproduction.

    Science.gov (United States)

    Wu, Chen; Twort, Victoria G; Crowhurst, Ross N; Newcomb, Richard D; Buckley, Thomas R

    2017-11-16

    Stick insects (Phasmatodea) have a high incidence of parthenogenesis and other alternative reproductive strategies, yet the genetic basis of reproduction is poorly understood. Phasmatodea includes nearly 3000 species, yet only the genome of Timema cristinae has been published to date. Clitarchus hookeri is a geographical parthenogenetic stick insect distributed across New Zealand. Sexual reproduction dominates in northern habitats but is replaced by parthenogenesis in the south. Here, we present a de novo genome assembly of a female C. hookeri and use it to detect candidate genes associated with gamete production and development in females and males. We also explore the factors underlying large genome size in stick insects. The C. hookeri genome assembly was 4.2 Gb, similar to the flow cytometry estimate, making it the second largest insect genome sequenced and assembled to date. Like the large genome of Locusta migratoria, the genome of C. hookeri is also highly repetitive and the predicted gene models are much longer than those from most other sequenced insect genomes, largely due to longer introns. Miniature inverted repeat transposable elements (MITEs), absent in the much smaller T. cristinae genome, is the most abundant repeat type in the C. hookeri genome assembly. Mapping RNA-Seq reads from female and male gonadal transcriptomes onto the genome assembly resulted in the identification of 39,940 gene loci, 15.8% and 37.6% of which showed female-biased and male-biased expression, respectively. The genes that were over-expressed in females were mostly associated with molecular transportation, developmental process, oocyte growth and reproductive process; whereas, the male-biased genes were enriched in rhythmic process, molecular transducer activity and synapse. Several genes involved in the juvenile hormone synthesis pathway were also identified. The evolution of large insect genomes such as L. migratoria and C. hookeri genomes is most likely due to the

  18. Effect of extra-pair paternity and parental quality on brood sex ratio in the scarlet rosefinch Carpodacus erythrinus

    Czech Academy of Sciences Publication Activity Database

    Poláková, Radka; Schnitzer, J.; Vinkler, Michal; Bryja, Josef; Munclinger, P.; Albrecht, Tomáš

    2012-01-01

    Roč. 61, 3-4 (2012), s. 225-232 ISSN 0139-7893 R&D Projects: GA MŠk LC06073; GA ČR GA206/06/0851 Institutional support: RVO:68081766 Keywords : sex allocation * extra-pair mating * parental attractiveness Subject RIV: EG - Zoology Impact factor: 0.494, year: 2012

  19. Seasonal dynamics in community structure, abundance, body size and sex ratio in two species of Neotropical annual fishes

    Czech Academy of Sciences Publication Activity Database

    Lanés, L. E. K.; Godoy, R. S.; Maltchik, L.; Polačik, Matej; Blažek, Radim; Vrtílek, Milan; Reichard, Martin

    2016-01-01

    Roč. 89, č. 5 (2016), s. 2345-2364 ISSN 0022-1112 Institutional support: RVO:68081766 Keywords : coastal floodplain * coexistence * Lagoa do Peixe * life cycle * sex-biased mortality * temporary habitat Subject RIV: EG - Zoology Impact factor: 1.519, year: 2016

  20. African American women and sexually transmitted infections: The contextual influence of unbalanced sex ratios and individual risk behaviors.

    Science.gov (United States)

    Oser, Carrie B; Pullen, Erin; Stevens-Watkins, Danelle; Perry, Brea L; Havens, Jennifer R; Staton-Tindall, Michele; Leukefeld, Carl G

    2017-10-01

    This study uses data from 564 African American women to examine the correlates of lifetime prevalence of a sexually transmitted infection (STI). Specifically, we test the effects of perceptions about the availability of African American males, five partner characteristics, and drug history. At the bivariate-level, women with an STI diagnosis were significantly more likely to have dated a man who was married, older, had sex with another man, involved in concurrent partnerships, and had been incarcerated. About half of the participants stated it was difficult to find an eligible African American male and attributed the limited pool of same-race partners to drug trafficking, a lack of monogamy, and high rates of incarceration. Multivariate analyses revealed having dated a man who had concurrent sexual partnerships or had been incarcerated, as well as drug use during sex were positively associated with ever having an STI. Individual and contextual implications are addressed.

  1. Laboratory studies on insecticide resistance, alcohol tolerance and sex ratio distortion by meiotic drive in the Mediterranean fruit fly, Ceratitis capitata (Wied.)

    International Nuclear Information System (INIS)

    Wood, R.J.

    1990-01-01

    Three approaches to developing a genetic sexing technique for the Mediterranean fruit fly (medfly), Ceratitis capitata (Wiedemann), are discussed. Laboratory studies in late third instar larvae of the medfly revealed a potential for dieldrin resistance. A programme of sib selection produced the DiR strain, more than 60x resistante to dieldrin with cross-resistance to other cyclodienes, HCH, malathion and permethrin. Adults were not resistant. Crosses showed dieldrin resistance to be monofactorial, subject to a modifying effect from the genetic background on the expression of the homozygote. The 'backcrossing with selection' technique was used to separate dieldrin and malathion resistance but, in the process, resistance to both insecticides was lost after four to eight generations. Attempts to induce male linkage of the R gene by X irradiation were unsuccessful. Further genetic studies on resistance are recommended. With a view to producing an ethanol sensitive strain homozygous for an ADH null mutation (Adh - /Adh - ), pentenol selection of late third instar larvae was carried out, combined with ethyl methane sulphonate (EMS) treatments of adults. This produced a maximum of 15x tolerance of pentenol but no associated change in ethanol tolerance. Electrophoresis (PAGE) showed that two major ADH systems were at their most active in late third instar larvae. A gene causing a male distorted sex ratio in the progeny of males carrying it was isolated after X irradiation. The expression of the gene, which appears to be an example of meiotic drive, was enhanced by reducing the ambient temperature of parent flies from 26 deg. C+-2.0 to 18 deg. C+-1.5 during days 2-5 of pupal development. Selection to increase the expression of the gene produced families with less than 20% females but sex ratio tended to revert towards normal in subsequent generations. A potential is seen for producing strains in which sex ratio can be regulated by temperature. (author). 30 refs, 5 figs, 2

  2. Sex-ratio, seasonality and long-term variation in maturation and spawning of the brown shrimp Crangon crangon (L.) in the German Bight (North Sea)

    Science.gov (United States)

    Siegel, V.; Damm, U.; Neudecker, T.

    2008-12-01

    Aspects of the reproductive and maturation biology of the brown shrimp Crangon crangon (L.) were studied in various subareas of the German Bight (North Sea). The size-specific sex ratio of C. crangon was examined based on length frequency distribution data. The sex ratio for the smallest size groups at which sex was determined was typically around 0.5, indicating an even ratio between males and females. The proportion of females decreased in the 30-45 mm size range. In length classes larger than 50 mm, the proportion of females constantly increases to 100% at around 60 mm total length. We concluded that sex reversal from male to female may not occur in C. crangon. Size at sexual maturity was determined from the proportion of ovigerous females. Size at maturity ( L 50) was estimated as 55.4 and 62.0 mm total length for spring and winter data, respectively. The seasonal spawning cycle was studied over the period 1958-2005. Between mid February and late June and for size classes larger than 65 mm ovigerous shrimps exceeded 80% and reached up to 100% of the females in the population. This period can be seen as the core spawning season. From early August to early December the proportion of ovigerous shrimps in the female population is very low. Interannual differences in the seasonal process are obvious with a dramatic decline in C. crangon reproductive success in the late 1980s. Various options are discussed for the reasons of the decline and recovery of the reproductive performance.

  3. Prenatal sex selection and girls' well-being: Evidence from India

    OpenAIRE

    Hu, Luojia; Schlosser, Analia

    2011-01-01

    In this paper, we study the impact of prenatal sex selection on the well-being of girls by analyzing changes in children's nutritional status and mortality during the years since the diffusion of prenatal sex determination technologies in India. We further examine various channels through which prenatal sex selection might affect girls’ outcomes. Using repeated cross-sections from a rich survey dataset, we show that high sex ratios at birth reflect the practice of sex selective abortion. We t...

  4. Effect of semen quality on human sex ratio in in vitro fertilization and intracytoplasmic sperm injection: an analysis of 27,158 singleton infants born after fresh single-embryo transfer.

    Science.gov (United States)

    Arikawa, Mikiko; Jwa, Seung Chik; Kuwahara, Akira; Irahara, Minoru; Saito, Hidekazu

    2016-04-01

    To evaluate the effect of semen quality on human sex ratio in in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Retrospective cohort study. Not applicable. A total of 27,158 singleton infants born between 2007 and 2012 after fresh single-embryo transfer. None. Proportion of male infants among liveborn infants. There were 14,996 infants born after IVF, 12,164 infants born after ICSI with ejaculated sperm, and 646 infants born after ICSI with nonejaculated sperm. The sex ratio of IVF was 53.1% (95% confidence interval [CI], 52.3-53.9); the sex ratio of ICSI with ejaculated and nonejaculated sperm demonstrated as statistically significant reduction (48.2%; 95% CI, 47.3-49.1 and 47.7%; 95% CI, 43.8-51.6, respectively). In IVF, lower sperm motility, including asthenozoospermia (sperm motility ratio compared with normal sperm (51.0%; 95% CI, 48.6-53.3 vs. 53.4%; 95% CI, 52.5-54.3). In ICSI with ejaculated sperm, there was no association between sperm motility and sex ratio. Sperm concentration was not associated with sex ratio in both IVF and ICSI. In IVF, lower sperm motility was associated with a statistically significant reduction in sex ratio; ICSI with either ejaculated or nonejaculated sperm was associated with a statistically significant reduction in sex ratio regardless of semen quality. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  5. Sex ratio and body size in Cobitis elongatoides and Sabanejewia balcanica (Cypriniformes; Cobitidae) from a thermal spring

    Czech Academy of Sciences Publication Activity Database

    Bohlen, Jörg; Freyhof, J.; Nolte, A.

    2008-01-01

    Roč. 57, 1-2 (2008), s. 191-197 ISSN 0139-7893. [International Conference Loaches of the genus Cobitis and related genera. Šibenik, 24.09.2006-29.09.2006] R&D Projects: GA ČR GA206/05/2556; GA AV ČR IAA600450508 Institutional research plan: CEZ:AV0Z50450515 Keywords : environmental sex determination * Fisher's principle * cobitine loach Subject RIV: EG - Zoology Impact factor: 0.522, year: 2008

  6. Estrogenic exposure affects metamorphosis and alters sex ratios in the northern leopard frog (Rana pipiens): identifying critically vulnerable periods of development.

    Science.gov (United States)

    Hogan, Natacha S; Duarte, Paula; Wade, Michael G; Lean, David R S; Trudeau, Vance L

    2008-05-01

    During the transformation from larval tadpole to juvenile frog, there are critical periods of metamorphic development and sex differentiation that may be particularly sensitive to endocrine disruption. The aim of the present study was to identify sensitive developmental periods for estrogenic endocrine disruption in the northern leopard frog (Rana pipiens) using short, targeted exposures to the synthetic estrogen, ethinylestradiol (EE2). Post-hatch tadpoles (Gosner stage 27) were exposed over five distinct periods of metamorphosis: early (stage 27-30), mid (stage 30-36), early and mid (stage 27-36), late (stage 36-42), and the entire metamorphic period (chronic; stage 27-42). For each period, animals were sampled immediately following the EE2 exposure and at metamorphic climax (stage 42). The effects of EE2 on metamorphic development and sex differentiation were assessed through measures of length, weight, developmental stage, days to metamorphosis, sex ratios and incidence of gonadal intersex. Our results show that tadpoles exposed to EE2 during mid-metamorphosis were developmentally delayed immediately following exposure and took 2 weeks longer to reach metamorphic climax. In the unexposed groups, there was low proportion (0.15) of intersex tadpoles at stage 30 and gonads appeared to be morphologically distinct (male and female) in all individuals by stage 36. Tadpoles exposed early in development displayed a strong female-biased sex ratio compared to the controls. Moreover, these effects were also seen at metamorphic climax, approximately 2-3 months after the exposure period, demonstrating that transient early life-stage exposure to estrogen can induce effects on the reproductive organs that persist into the beginning of adult life-stages.

  7. Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice.

    Science.gov (United States)

    Mineur, Yann S; Bentham, Matthew P; Zhou, Wen-Liang; Plantenga, Margreet E; McKee, Sherry A; Picciotto, Marina R

    2015-10-01

    The a2A-noradrenergic agonist guanfacine can decreases stress-induced smoking in female, but not male, human smokers. It is not known whether these effects are due to effects on mood regulation and/or result from nicotinic-cholinergic interactions. The objective of the study was to determine whether there are sex differences in the effect of guanfacine in tests of anxiolytic and antidepressant efficacy in mice at baseline and in a hypercholinergic model of depression induced by the acetylcholinesterase inhibitor physostigmine. The effects of guanfacine were measured in the light/dark box, tail suspension, and the forced swim test in female and male C57BL/6J mice. In parallel, electrophysiological properties were evaluated in the prefrontal cortex, a critical brain region involved in stress responses. c-fos immunoreactivity was measured in other brain regions known to regulate mood. Despite a baseline sex difference in behavior in the forced swim test (female mice were more immobile), guanfacine had similar, dose-dependent, antidepressant-like effects in mice of both sexes (optimal dose, 0.15 mg/kg). An antidepressant-like effect of guanfacine was also observed following pre-treatment with physostigmine. A sex difference in the paired-pulse ratio in the prefrontal cortex (PFC) (male, 1.4; female, 2.1) was observed at baseline that was normalized by guanfacine. Other brain areas involved in cholinergic control of depression-like behaviors, including the basolateral amygdala and lateral septum, showed sex-specific changes in c-fos expression. Guanfacine has a robust antidepressant-like effect and can reverse a depression-like state induced by increased acetylcholine (ACh) signaling. These data suggest that different brain areas are recruited in female and male mice, despite similar behavioral responses to guanfacine.

  8. A cohort study of the association between secondary sex ratio and parental exposure to polybrominated biphenyl (PBB and polychlorinated biphenyl (PCB

    Directory of Open Access Journals (Sweden)

    Terrell Metrecia L

    2009-08-01

    Full Text Available Abstract Background Polybrominated biphenyl (PBB, a brominated flame retardant, was accidently mixed into animal feed in Michigan (1973–1974 resulting in human exposure through consumption of contaminated meat, milk and eggs. Beginning in 1976 individuals who consumed contaminated products were enrolled in the Michigan Long-Term PBB Study. This cohort presents a unique opportunity to study the association between parental exposures to PBB and offspring sex ratio. Methods We identified offspring of female PBB cohort participants (born 1975–1988 and obtained electronic birth records for those born in the state of Michigan. We linked this information to parental serum PBB and PCB concentrations collected at enrollment into the cohort. We modeled the odds of a male birth with generalized estimating equations accounting for the non-independence of siblings born to the same parents. We explored potential confounders: parental age and education at offspring's birth, parental body mass index at cohort enrollment, birth order, gestational age and year of offspring's birth. Results The overall proportion of male offspring among 865 live births to cohort mothers was 0.542. This was higher than the national male proportion of 0.514 (binomial test: p = 0.10. When both parents were in the cohort (n = 300, we found increased odds of a male birth with combined parents' enrollment PBB exposure ≥ the median concentrations (3 μg/L for mothers; 6 μg/L for fathers compared to combined parents' PBB exposure Conclusion This study adds to the body of literature on secondary sex ratio and exposure to environmental contaminants. In this population, combined parental exposure to PBBs or PCBs increased the odds of a male birth. Further research is needed to corroborate these findings and shed light on the biological mechanisms by which these types of chemicals may influence the secondary sex ratio.

  9. An adaptive annual rhythm in the sex of first pigeon eggs

    NARCIS (Netherlands)

    Dijkstra, Cor; Riedstra, Bernd; Dekker, Arjan; Goerlich, Vivian C.; Daan, Serge; Groothuis, Ton G. G.

    When the reproductive value of male and female offspring varies differentially, parents are predicted to adjust the sex ratio of their offspring to maximize their fitness (Trivers and Willard, Science 179:90-92, 1973). Two factors have been repeatedly linked to skews in avian offspring sex ratio.

  10. Sex ratio of the offspring of Sprague-Dawley rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in utero and lactationally in a three-generation study

    International Nuclear Information System (INIS)

    Rowlands, J.C.; Budinsky, R.A.; Aylward, L.L.; Faqi, A.S.; Carney, E.W.

    2006-01-01

    Reports of a decreased male/female sex ratio in children born to males exposed to TCDD in Seveso, Italy, at a young age have sparked examinations of this endpoint in other populations exposed to TCDD or related compounds. Overall, the male/female sex ratio results reported in these studies, with slightly different age-exposed male populations, have shown mixed results. Experimental studies of the effects of in utero exposure to TCDD in laboratory animals have reported no effect on the f 1 sex ratio and mixed results for the sex ratio of the f 2 generation. In order to better understand the potential effects of TCDD on second generation sex ratio, we retrieved archived data from a comprehensive three-generation feeding study of TCDD in rats that was conducted and published in the 1970s, but which did not publish data on sex ratio of the offspring [Murray, F.J., Smith, F.A., Nitschke, K.D., Humiston, C.G., Kociba, R.J., Schwetz, B.A., 1979. Three-generation reproduction study of rats given 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the diet. Toxicol. Appl. Pharmacol. 50, 241-252]. A re-examination of the original Murray et al. data found no statistically significant treatment-related changes in postnatal day 1 sex ratio in any generation of treated animals, consistent with one other relatively large study reporting on this endpoint. We discuss mechanistic data underlying a potential effect of TCDD on this endpoint. We conclude that the inconsistency in findings on sex ratio of the offspring of male rats exposed to TCDD in utero is likely due to random variation associated with a relatively small sample size, although differences between studies in strain of rat, dose regimen, and day of ascertainment of sex ratio cannot be ruled out

  11. Sex-specific mediation effect of the right fusiform face area volume on the association between variants in repeat length of AVPR1A RS3 and altruistic behavior in healthy adults.

    Science.gov (United States)

    Wang, Junping; Qin, Wen; Liu, Feng; Liu, Bing; Zhou, Yuan; Jiang, Tianzi; Yu, Chunshui

    2016-07-01

    Microsatellite variants in the arginine vasopressin receptor 1A gene (AVPR1A) RS3 have been associated with normal social behaviors variation and autism spectrum disorders (ASDs) in a sex-specific manner. However, neural mechanisms underlying these associations remain largely unknown. We hypothesized that AVPR1A RS3 variants affect altruistic behavior by modulating the gray matter volume (GMV) of specific brain regions in a sex-specific manner. We investigated 278 young healthy adults using the Dictator Game to assess altruistic behavior. All subjects were genotyped and main effect of AVPR1A RS3 repeat polymorphisms and interaction of genotype-by-sex on the GMV were assessed in a voxel-wise manner. We observed that male subjects with relatively short repeats allocated less money to others and exhibited a significantly smaller GMV in the right fusiform face area (FFA) compared with male long homozygotes. In male subjects, the GMV of the right FFA exhibited a significant positive correlation with altruistic behavior. A mixed mediation and moderation analysis further revealed both a significant mediation effect of the GMV of the right FFA on the association between AVPR1A RS3 repeat polymorphisms and allocation sums and a significant moderation effect of sex (only in males) on the mediation effect. Post hoc analysis showed that the GMV of the right FFA was significantly smaller in male subjects carrying allele 426 than in non-426 carriers. These results suggest that the GMV of the right FFA may be a potential mediator whereby the genetic variants in AVPR1A RS3 affect altruistic behavior in healthy male subjects. Hum Brain Mapp 37:2700-2709, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  12. Does the radiation from the interim storage in Gorleben affect the sex ratio of newborn children?; Beeinflusst die Strahlung aus dem Zwischenlager in Gorleben das Geschlechterverhaeltnis von Neugeborenen?

    Energy Technology Data Exchange (ETDEWEB)

    Engelmann, H.W.; Schulze, H.; Wede, S. [GNS Gesellschaft fuer Nuklear-Service mbH, Gorleben (Germany); Mueller, S. [Studsvik GmbH, Pforzheim (Germany)

    2015-07-01

    In the professional world but especially in public, the question is discussed whether ionizing radiation from nuclear facilities has a significant impact on the secondary sex ratio of newborn children in the vicinity of the plants. This issue is of exceptional importance in the region around Gorleben, where the opposition to nuclear facilities and activities for decades is particularly strong. At the site borders of the interim storage facility (TBL-G) of GNS the effective individual dose is about 0.2 mSv per year, mainly caused by neutron irradiation from 108 casks with high-level radioactive waste from reprocessing. In the surrounding villages there is no radiation measurable. Statistical studies allegedly have shown evidence that in some villages in the area and during certain periods, proportionately fewer girls were born in comparison to the average for the Federal Republic of Germany. Based on these purely statistical results henceforward was also alleged that neutron-induced secondary effects such as activation or secondary gamma radiation would be responsible for it. Monte Carlo calculations and special measurements yielded values of the dose at the plant border for activation products less than E-04 mSv/a and for secondary gamma radiation of about E-03 mSv/a. These results indicate that the ionizing radiation from the Gorleben interim storage facility cannot be held accountable for shifts of the secondary sex ratio.

  13. Socioeconomic status and sex ratios at birth in Sweden: No evidence for a Trivers-Willard effect for a wide range of status indicators.

    Science.gov (United States)

    Kolk, Martin; Schnettler, Sebastian

    2016-01-01

    This study examines if there exists a positive association between socioeconomic status and the proportion of male births in humans, as proposed by Trivers and Willard in 1973, using individual-level data drawn from the complete population of Sweden. We examine more than 3,000,000 births between 1960 and 2007 using administrative register data with comprehensive information on various dimensions of socioeconomic status. We use six different operationalizations of socioeconomic status, including earnings, post-transfer income (including government allowances), wealth, parental wealth, educational level, and occupational class. We apply regression models that compare both changes in status for the same woman over time and differences in status across different women. We also measure socioeconomic status both at the year of child birth and the year of conception. Our results show the absence of any relationship between socioeconomic status and sex ratios, using a large number of different operationalizations of status. We conclude that no substantive relationship between socioeconomic status and sex ratios exists for the population and period of our study. © 2015 Wiley Periodicals, Inc.

  14. Sex ratio at birth: scenario from normal- and high-level natural radiation areas of Kerala coast in south-west India

    International Nuclear Information System (INIS)

    Koya, P.K.M.; Jaikrishan, G.; Sudheer, K.R.; Madhusoodhanan, M.; Jagadeesan, C.K.; Das, Birajalaxmi; Andrews, V.J.

    2015-01-01

    Newborns were monitored for congenital malformations in four government hospitals located in high-level (ambient dose >1.5 mGy/year) and normal-level (≤1.5 mGy/year) natural radiation areas of Kerala, India, from August 1995 to December 2012. Sex ratio at birth (SRB) among live singleton newborns and among previous children, if any, of their mothers without history of any abortion, stillbirth or twins is reported here. In the absence of environmental stress or selective abortion of females, global average of SRB is about 1050 males to 1000 females. A total of 151,478 singleton, 1031 twins, 12 triplets and 1 quadruplet deliveries were monitored during the study period. Sex ratio among live singleton newborns was 1046 males (95 % CI 1036-1057) for 1000 females (77,153 males:73,730 females) and was comparable to the global average. It was similar in high-level and normal-level radiation areas of Kerala with SRB of 1050 and 1041, respectively. It was consistently more than 1000 and had no association with background radiation levels, maternal and paternal age at birth, parental age difference, gravida status, ethnicity, consanguinity or year of birth. Analysis of SRB of the children of 139,556 women whose reproductive histories were available suggested that couples having male child were likely to opt for more children and this, together with enhanced rate of males at all birth order, was skewing the overall SRB in favour of male children. Though preference for male child was apparent, extreme steps of sex-selective abortion or infanticide were not prevalent. (orig.)

  15. Brood size and sex ratio in response to host quality and wasp traits in the gregarious parasitoid Oomyzus sokolowskii (Hymenoptera: Eulophidae

    Directory of Open Access Journals (Sweden)

    Xianwei Li

    2017-01-01

    Full Text Available This laboratory study investigated whether the larval-pupal parasitoid Oomyzus sokolowskii females adjust their brood size and sex ratio in response to body size and stage of Plutella xylostella larval hosts, as well as to their own body size and the order of oviposition. These factors were analyzed using multiple regression with simultaneous entry of them and their two-way interactions. Parasitoids brood size tended to increase with host body size at parasitism when the 4th instar larval host was attacked, but did not change when the 2nd and 3rd instar larvae were attacked. Parasitoids did not vary in brood size according to their body size, but decreased with their bouts of oviposition on a linear trend from 10 offspring adults emerged per host in the first bout of oviposition down to eight in the third. Parasitoid offspring sex ratio did not change with host instar, host body weight, wasp body size, and oviposition bout. Proportions of male offspring per brood were from 11% to 13% from attacking the 2nd to 4th instar larvae and from 13% to 16% across three successive bouts of oviposition, with a large variation for smaller host larvae and wasps. When fewer than 12 offspring were emerged from a host, one male was most frequently produced; when more than 12 offspring were emerged, two or more males were produced. Our study suggests that O. sokolowskii females may optimize their clutch size in response to body size of mature P. xylostella larvae, and their sex allocation in response to clutch size.

  16. Sex ratio at birth: scenario from normal- and high-level natural radiation areas of Kerala coast in south-west India

    Energy Technology Data Exchange (ETDEWEB)

    Koya, P.K.M.; Jaikrishan, G.; Sudheer, K.R. [Bhabha Atomic Research Centre, Low Level Radiation Research Laboratory, Low Level Radiation Research Section, Radiation Biology and Health Sciences Division, Bio-Science Group, Kollam (India); Madhusoodhanan, M. [Victoria Hospital, Department of Paediatrics, Kollam (India); Jagadeesan, C.K. [Directorate of Health Services, Thiruvananthapuram (India); Das, Birajalaxmi [Bhabha Atomic Research Centre, Low Level Radiation Research Section, Radiation Biology and Health Sciences Division, Bio-Science Group, Mumbai (India); Andrews, V.J.

    2015-11-15

    Newborns were monitored for congenital malformations in four government hospitals located in high-level (ambient dose >1.5 mGy/year) and normal-level (≤1.5 mGy/year) natural radiation areas of Kerala, India, from August 1995 to December 2012. Sex ratio at birth (SRB) among live singleton newborns and among previous children, if any, of their mothers without history of any abortion, stillbirth or twins is reported here. In the absence of environmental stress or selective abortion of females, global average of SRB is about 1050 males to 1000 females. A total of 151,478 singleton, 1031 twins, 12 triplets and 1 quadruplet deliveries were monitored during the study period. Sex ratio among live singleton newborns was 1046 males (95 % CI 1036-1057) for 1000 females (77,153 males:73,730 females) and was comparable to the global average. It was similar in high-level and normal-level radiation areas of Kerala with SRB of 1050 and 1041, respectively. It was consistently more than 1000 and had no association with background radiation levels, maternal and paternal age at birth, parental age difference, gravida status, ethnicity, consanguinity or year of birth. Analysis of SRB of the children of 139,556 women whose reproductive histories were available suggested that couples having male child were likely to opt for more children and this, together with enhanced rate of males at all birth order, was skewing the overall SRB in favour of male children. Though preference for male child was apparent, extreme steps of sex-selective abortion or infanticide were not prevalent. (orig.)

  17. The effects of bis(tributyltin) oxide on the development, reproduction and sex ratio of calanoid copepod Pseudodiaptomus marinus

    Science.gov (United States)

    Huang, Ying; Zhu, Liyan; Liu, Guangxing

    2006-08-01

    In order to study the biological effects by bis(tributyltin) oxide (TBTO) exposure, chronic toxicity tests were conducted on the calanoid copepod Pseudodiaptomus marinus over two generations. The results indicated that nauplii were more sensitive than copepodites. F1 copepods were more vulnerable than F0 copepods and a drastic increase in mortality was observed as the TBTO concentration became higher. Exposure of copepods to 60 ng l -1 TBTO concentration reduced the fecundity and resulted in some females being infecund (in the F0 generation). The time to the first egg sac for females in the F1 generation exposed to 6 ng l -1 TBTO concentration was significantly reduced, and the fecundity of this generation was increased. The female-to-male ratio in the F1 generation exposed to 20 ng l -1 TBTO concentration was significantly reduced. These results show that the current ambient TBT concentration may influence populations of copepods in the coastal environment.

  18. Secular Trends and Latitude Gradients in Sex Ratios at Birth in Czechoslovakia and the Post-Czechoslovakian States

    Directory of Open Access Journals (Sweden)

    Victor Grech

    2012-01-01

    Full Text Available Latitude gradients and secular trends in Europe and North America have been found in the male-female ratio at birth (M/F: male births divided by total births which is expected to be 0.515. Annual national data for Czechoslovakia and the post-Czechoslovakian (Czech Republic and Slovakia countries for male and female live births were obtained from the World Health Organisation and analysed with contingency tables. This study analysed 13,123,538 live births. An overall decreasing trend in M/F was found (p < 00001. No latitude gradient was noted. There was an overall deficit of 15,232 male births based on an M/F of 0.515. M/F is declining in this region, despite well developing economies that have resisted the worldwide slowdown. An interplay of several poorly understood factors is likely.

  19. Effects of long term feeding of Quillaja saponins on sex ratio, muscle and serum cholesterol and LH levels in Nile tilapia (Oreochromis niloticus (L)).

    Science.gov (United States)

    Francis, George; Levavi-Sivan, Berta; Avitan, Ayelet; Becker, Klaus

    2002-12-01

    Seventeen-day-old Nile tilapia fry were fed a standard diet (C) or diets containing 50-700 mg kg(-1) Quillaja saponin (QS) extract (groups S50, S150, S300, S500 and S700). After the first 8 weeks, 30 randomly selected tilapia from each of the treatments were placed in separate aquaria and fed the standard diet without saponins from then on (these were designated S50/C, S150/C, S300/C, S500/C and S700/C). The fish grew from an initial average weight of approximately 30 mg to a final average weight of 79 g during the 6-month feeding period. The difference between the average weight of C-fed tilapia and the treatment with the highest average weight after 6 months was 53.5%. The sex ratio of tilapia in the saponin-fed groups deviated from the normal 50:50 male:female ratio, with the S700 group showing a significantly higher number of males. Quillaja saponin stimulated LH release from dispersed tilapia pituitary cells in vitro. This effect was abolished in the presence of dilute calf serum. Serum LH values did not show any diet-dependent trend in either male or female tilapia in vivo. In both continuously saponin-fed and only-initially saponin-fed groups, the average serum (but not muscle) cholesterol levels in males showed an increasing trend (R(2) values of 0.62 and 0.69) with increasing dietary saponin level. It was concluded that dietary QS has the potential to change the sex-ratio in favour of males. More investigations are required to determine the mechanism of action and the optimum dietary level of QS for maximum effects.

  20. Sex, age, pubertal development and use of oral contraceptives in relation to serum concentrations of DHEA, DHEAS, 17α-hydroxyprogesterone, Δ4-androstenedione, testosterone and their ratios in children, adolescents and young adults.

    Science.gov (United States)

    Søeborg, Tue; Frederiksen, Hanne; Mouritsen, Annette; Johannsen, Trine Holm; Main, Katharina Maria; Jørgensen, Niels; Petersen, Jørgen Holm; Andersson, Anna-Maria; Juul, Anders

    2014-11-01

    The influence of sex, age, pubertal development and oral contraceptives on dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS), 17α-hydroxyprogesterone (17-OHP), Δ4-androstenedione (Adione), testosterone (T), calculated free testosterone (fT), free androgen index (FAI) and selected ratios in 1798 serum samples from healthy children, adolescents and young adults was evaluated. Samples were analyzed by Turboflow-LC-MS/MS. Sex hormone-binding globulin was analyzed by immunoassay. All steroid metabolite concentrations were positively associated with age and pubertal development in both sexes and generally higher in males than in females except for Adione. The pubertal rise in T in males was more pronounced compared to females, reflecting contribution from the testes. Ratios between steroid metabolites varied and depended on sex and age. All ratios were lower during infancy compared to later in life. Use of oral contraceptives significantly lowered serum concentrations of all steroid metabolites, fT, FAI, the 17-OHP/Adione, the Adione/T and the DHEA/Adione ratios, but not the DHEA/DHEAS ratio. We provide reference ranges for DHEA, DHEAS, 17-OHP, Adione, T, fT, FAI and selected ratios in relation to sex, age and pubertal development. Use of oral contraceptives strongly influences adrenal steroidogenesis and should be considered when diagnosing and monitoring treatment of patients with disorders of sex development. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Signal-to-noise ratio of bilateral nonimaging transcranial Doppler recordings of the middle cerebral artery is not affected by age and sex.

    Science.gov (United States)

    Katsogridakis, Emmanuel; Dineen, Nicky E; Brodie, Fiona G; Robinson, Thompson G; Panerai, Ronney B

    2011-04-01

    Differences between transcranial Doppler ultrasonography (TCD) recordings of symmetrical vessels can show true physiologic differences, but can also be caused by measurement error and other sources of noise. The aim of this project was to assess the influence of noise on estimates of dynamic cerebral autoregulation (dCA), and of age, sex and breathing manoeuvres on the signal-to-noise ratio (SNR). Cerebral blood flow (CBF) was monitored in 30 young (60 years) during baseline conditions, breath-holding and hyperventilation. Noise was defined as the difference between beat-to-beat values of the two mean CBF velocity (CBFV) signals. Magnitude squared coherence estimates of noise vs. ABP and ABP vs. CBFV were obtained and averaged. A similar approach was adopted for the CBFV step response. The effect of age and breathing manoeuvre on the SNR was assessed using a two-way analysis of variance (ANOVA), whilst the effect of sex was investigated using a Student's t test. No significant differences were observed in SNR (baseline 6.07 ± 3.07 dB and 7.33 ± 3.84 dB, breath-hold: 13.53 ± 3.93 dB and 14.64 ± 4.52 dB, and hyperventilation: 14.69 ± 4.04 dB and 14.84 ± 4.05 dB) estimates between young and old groups, respectively. The use of breathing manoeuvres significantly improved the SNR (p < 10(-4)) without a significant difference between manoeuvres. Sex does not appear to have an effect on SNR (p = 0.365). Coherence estimates were not influenced by the SNR, but significant differences were found in the amplitude of the CBFV step response. Copyright © 2011 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  2. Impact of consanguineous marriages and degrees of inbreeding on fertility, child mortality, secondary sex ratio, selection intensity, and genetic load: a cross-sectional study from Northern India.

    Science.gov (United States)

    Fareed, Mohd; Kaisar Ahmad, Mir; Azeem Anwar, Malik; Afzal, Mohammad

    2017-01-01

    The aim of our study was to understand the relationship between consanguineous marriages and reproductive outcomes. A total of 999 families were recruited from five Muslim populations of Jammu region. Family pedigrees were drawn to access the family history and inbreeding status in terms of coefficient of inbreeding (F). Fertility, mortality, secondary sex ratio, selection intensity, and lethal equivalents were measured using standard methods. The significant differences for gross fertility was found to be higher among inbred groups as compared to the unrelated families (P consanguineous families of all populations in comparison with the non-consanguineous family groups. Moreover, the prenatal and postnatal child mortality rates (i.e., U5MR and U18MR) have presented a persuasive increase with an upsurge in the homozygosity level. The mortality rate was found to be maximum among families with the highest value of coefficient of inbreeding (F). The selection intensity (SI) also showed inflations among families with respect to their increasing inbreeding coefficients. The greater values of lethal equivalents per gamete (LEs/gamete) were observed for autosomal inheritance in comparison with sex-linked inheritance. Our conclusive assessment brings out the deleterious consequence of consanguineous marriages on reproductive outcomes.

  3. Predicting the variation in Echinogammarus marinus at its southernmost limits under global warming scenarios: can the sex-ratio make a difference?

    Science.gov (United States)

    Guerra, Alexandra; Leite, Nuno; Marques, João Carlos; Ford, Alex T; Martins, Irene

    2014-01-01

    Understanding the environmental parameters that constrain the distribution of a species at its latitudinal extremes is critical for predicting how ecosystems react to climate change. Our first aim was to predict the variation in the amphipod populations of Echinogammarus marinus from the southernmost limit of its distribution under global warming scenarios. Our second aim was to test whether sex-ratio fluctuations - a mechanism frequently displayed by amphipods - respond to the variations in populations under altered climate conditions. To achieve these aims, scenarios were run with a validated model of E. marinus populations. Simulations were divided into: phase I - simulation of the effect of climate change on amphipod populations, and phase II - simulation of the effect of climate change on populations with male and female proportions. In both phases, temperature (T), salinity (S) and temperature and salinity (T-S) were tested. Results showed that E. marinus populations are highly sensitive to increases in temperature (>2 °C), which has adverse effects on amphipod recruitment and growth. Results from the climate change scenarios coupled with the sex-ratio fluctuations depended largely on the degree of female bias within population. Temperature increase of 2 °C had less impact on female-biased populations, particularly when conjugated with increases in salinity. Male-biased populations were highly sensitive to any variation in temperature and/or salinity; these populations exhibited a long-term decline in density. Simulations in which temperature increased more than 4 °C led to a continuous decline in the E. marinus population. According to this work, E. marinus populations at their southernmost limit are vulnerable to global warming. We anticipate that in Europe, temperature increases of 2 °C will incite a withdrawal of the population of 5°N from the amphipod species located at southernmost geographical borders. This effect is discussed in relation to the

  4. Sex, age, pubertal development and use of oral contraceptives in relation to serum concentrations of DHEA, DHEAS, 17α-hydroxyprogesterone, Δ4-androstenedione, testosterone and their ratios in children, adolescents and young adults

    DEFF Research Database (Denmark)

    Søeborg, Tue; Frederiksen, Hanne; Mouritsen, Annette

    2014-01-01

    The influence of sex, age, pubertal development and oral contraceptives on dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS), 17α-hydroxyprogesterone (17-OHP), Δ4-androstenedione (Adione), testosterone (T), calculated free testosterone (fT), free androgen index (FAI) and selected ratios in 1798...... serum samples from healthy children, adolescents and young adults was evaluated. Samples were analyzed by Turboflow-LC-MS/MS. Sex hormone-binding globulin was analyzed by immunoassay. All steroid metabolite concentrations were positively associated with age and pubertal development in both sexes....... Use of oral contraceptives significantly lowered serum concentrations of all steroid metabolites, fT, FAI, the 17-OHP/Adione, the Adione/T and the DHEA/Adione ratios, but not the DHEA/DHEAS ratio. We provide reference ranges for DHEA, DHEAS, 17-OHP, Adione, T, fT, FAI and selected ratios in relation...

  5. The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status

    DEFF Research Database (Denmark)

    Gjesing, Anette P; Vestmar, Marie A; Jørgensen, Torben

    2011-01-01

    Background: We aimed to evaluate the effects of the G-allele of rs6232 and the C-allele of rs6235 within PCSK1 on measures of body fat and glucose homeostasis in Danish individuals and to assess interactions of genotypes with age, sex and glucose tolerance status. Data were included in meta.......008) and increased waist-to-hip ratio of 0.004 (0.0005–0.008, p = 0.027). In the meta-analyses where men and women were combined, the rs6232 G-allele associated with increased waist-to-hip ratio (p = 0.02) and the rs6235 C-allele associated with increased waist circumference (p = 0.01). Furthermore, the rs6235 C......-allele was associated nominally with a 0.6% (0.1–1%, p = 0.01) reduction in fasting glucose, it interacted with glucose tolerance status for traits related to glucose metabolism and analysis among individuals having abnormal glucose tolerance revealed a 5% (20.7–9%, p = 0.02) elevated level of acute insulin response...

  6. Deployment Repeatability

    Science.gov (United States)

    2016-04-01

    evaluating the deployment repeatability builds upon the testing or analysis of deployment kinematics (Chapter 6) and adds repetition. Introduction...material yield or failure during a test. For the purposes of this chapter, zero shift will refer to permanent changes in the structure, while reversible ...the content of other chapters in this book: Gravity Compensation (Chapter 4) and Deployment Kinematics and Dynamics (Chapter 6). Repeating the

  7. Correlation of maternal age, gravida status, major malformations, stillbirth and sex ratio in high level natural radiation areas of Kerala coast

    International Nuclear Information System (INIS)

    Sudheer, K.R.; Koya, P.K.M.; Jaikrishan, G.; Das, Birajalaxmi

    2016-01-01

    As a part of the ongoing study on biological and health effects of chronic low dose and/or dose rate on human population, consecutive births were monitored in selected Govt. hospitals located in normal and high level natural radiation areas (HLNRA) of Kerala coast. This area is unique because of its vast population size and varied range of background radiation level due to natural deposit of monazite containing thorium. The objective is to elucidate the role of chronic low dose radiation, if any, on the adverse pregnancy outcome. Since 1995, ∼1,70,000 newborns were monitored in this area, of which 74,238 singleton first births were monitored. Of these, 634 (0.85%) cases were observed with detectable major congenital malformations (that include serious structural, functional or cosmetic disability requiring surgical or medical management) and 240 (0.32%) cases were stillborn. Sex ratio at first birth was observed in the ratio of 1050 males to 1000 females. The distribution of age at marriage of the mothers was stratified into the following groups: d"18 years (15.5%), 19 20 years (25.9%), 21 22 years (25.6%), 23 24 years (17.2%) and >25 years (15.8%). It was observed that about 78.9% mothers had their first birth within one year of marriage, 13.7% had their first birth within 1.1 2 years and 5.2% within 2.1 4 years. About 2.2% (1613) mothers had their first child after 4 years or more. Individual, combined and interactive effects of age at marriage, first birth interval (first gravida status), background radiation levels and gender of the newborn on major congenital malformation and stillbirth will be discussed. (author)

  8. Effects of salinity on egg and fecal pellet production, development and survival, adult sex ratio and total life span in the calanoid copepod, Acartia tonsa: a laboratory study

    Science.gov (United States)

    Shayegan, Majid; Esmaeili Fereidouni, Abolghasem; Agh, Naser; Jani Khalili, Khosrow

    2016-07-01

    The effects of salinity on the copepod, Acartia tonsa in terms of daily egg production rate (EPR), hatching success, fecal pellet production rate (FPR), naupliar development time and survival, sex ratio, and total life span were determined in laboratory conditions through three experiments. In experiment 1, EPR, hatching success, and FPR of individual females were monitored at salinities of 13, 20, 35 and 45 during short-periods (seven consecutive days). Results show EPR was affected by salinity with the highest outputs recorded at 20 and 35, respectively, which were considerably higher than those at 13 and 45. Mean FPR was also higher in 35 and 20. In experiment 2, the same parameters were evaluated over total life span of females (long-term study). The best EPR and FPR were observed in 35, which was statistically higher than at 13 and 20. In experiment 3, survival rates of early nauplii until adult stage were lowest at a salinity of 13. The development time increased with increasing of salinity. Female percentage clearly decreased with increasing salinity. Higher female percentages (56.7% and 52.2%, respectively) were significantly observed at two salinities of 13 and 20 compared to that at 35 (25%). Total longevity of females was not affected by salinity increment. Based on our results, for mass culture we recommend that a salinity of 35 be adopted due to higher reproductive performances, better feeding, and faster development of A. tonsa.

  9. Inherited Sterility Induced in Progeny of Gamma Irradiated Males Spiny Bollworm, Earias insulana Boisd. II. Effect on Larval and Pupal Mortality, Development and Sex Ratio

    International Nuclear Information System (INIS)

    Amin, A.R.H.; Sallam, H.A.; Mohamed, H.F.

    2010-01-01

    Spiny bollworm, Earias insulana Boisd. adult males were irradiated with sub sterilizing doses of 50,80,100 and 150 Gray (Gy) of gamma radiation. The number of surviving larvae was dose dependant and larval/pupal mortality increased as the dose applied to P1 males was increased. The larval mortality among F3 was reduced compared with that of the F1 and F2. The average developmental time from egg hatch to adult emergence at the four tested doses was slightly affected among the progeny descendant of irradiated P1 males through the three successive generations. The percentage of adult emergence was evidently reduced among F1 and F2 progeny resulting from parental males exposed to the three higher irradiation doses (80,100 and 150 Gy).The sex ratio was slightly altered in favor of males among the majority of all treatments. Raman studies of irradiated and unirradiated stones at different temperatures and irradiation times showed a relation between the bands of scattered peaks corresponding to (OH) stretching modes of vibration with the color changes

  10. Can Sex Differences in Science Be Tied to the Long Reach of Prenatal Hormones? Brain Organization Theory, Digit Ratio (2D/4D), and Sex Differences in Preferences and Cognition.

    Science.gov (United States)

    Valla, Jeffrey; Ceci, Stephen J

    2011-03-01

    Brain organization theory posits a cascade of physiological and behavioral changes initiated and shaped by prenatal hormones. Recently, this theory has been associated with outcomes including gendered toy preference, 2D/4D digit ratio, personality characteristics, sexual orientation, and cognitive profile (spatial, verbal, and mathematical abilities). We examine the evidence for this claim, focusing on 2D/4D and its putative role as a biomarker for organizational features that influence cognitive abilities/interests predisposing males toward mathematically and spatially intensive careers. Although massive support exists for early brain organization theory overall, there are myriad inconsistencies, alternative explanations, and outright contradictions that must be addressed while still taking the entire theory into account. Like a fractal within the larger theory, the 2D/4D hypothesis mirrors this overall support on a smaller scale while likewise suffering from inconsistencies (positive, negative, and sex-dependent correlations), alternative explanations (2D/4D related to spatial preferences rather than abilities per se), and contradictions (feminine 2D/4D in men associated with higher spatial ability). Using the debate over brain organization theory as the theoretical stage, we focus on 2D/4D evidence as an increasingly important player on this stage, a demonstrative case in point of the evidential complexities of the broader debate, and an increasingly important topic in its own right.

  11. How Good Is Your Rule of Thumb? Validating Male-to-Female Case Ratio as a Proxy for Men Who Have Sex With Men Involvement in N. gonorrhoeae Incidence at the County Level.

    Science.gov (United States)

    Stenger, Mark; Bauer, Heidi; Klingler, Ellen; Bell, Teal; Donnelly, Jennifer; Eaglin, Margaret; Jespersen, Megan; Madera, Robbie; Mattson, Melanie; Torrone, Elizabeth

    2018-03-01

    Lacking information on men who have sex with men (MSM) for most reported cases, sexually transmitted disease (STD) programs in the United States have used crude measures such as male-to-female case ratios (MFCR) as a rule of thumb to gauge MSM involvement at the local level, primarily with respect to syphilis cases in the past. Suitability of this measure for gonorrhea incidence has not previously been investigated. A random sample of gonorrhea cases reported from January 2010 through June 2013 were interviewed in selected counties participating in the STD Surveillance Network to obtain gender of sex partners and history of transactional sex. Weighted estimates of proportion of cases among MSM and proportion reporting transactional sex were developed; correlation between MFCR and proportion MSM was assessed. Male-to-female case ratio ranged from 0.66 to 8.7, and the proportion of cases occurring among MSM varied from 2.5% to 62.3%. The MFCR was strongly correlated with proportion of cases among MSM after controlling for transactional sex (Pearson partial r = 0.754, P < 0.0001). Male-to-female case ratio for gonorrhea at the county level is a reliable proxy measure indicating MSM involvement in gonorrhea case incidence and should be used by STD programs to tailor their programmatic mix to include MSM-specific interventions.

  12. The discriminative ability of waist circumference, body mass index and waist-to-hip ratio in identifying metabolic syndrome: Variations by age, sex and race.

    Science.gov (United States)

    Cheong, Kee C; Ghazali, Sumarni M; Hock, Lim K; Subenthiran, Soobitha; Huey, Teh C; Kuay, Lim K; Mustapha, Feisul I; Yusoff, Ahmad F; Mustafa, Amal N

    2015-01-01

    Many studies have suggested that there is variation in the capabilities of BMI, WC and WHR in predicting cardiometabolic risk and that it might be confounded by gender, ethnicity and age group. The objective of this study is to examine the discriminative abilities of body mass index (BMI), waist circumference (WC) and waist-hip ratio (WHR) to predict two or more non-adipose components of the metabolic syndrome (high blood pressure, hypertriglyceridemia, low high density lipoprotein-cholesterol and high fasting plasma glucose) among the adult Malaysian population by gender, age group and ethnicity. Data from 2572 respondents (1044 men and 1528 women) aged 25-64 years who participated in the Non Communicable Disease Surveillance 2005/2006, a population-based cross sectional study, were analysed. Participants' socio-demographic details, anthropometric indices (BMI, WC and WHR), blood pressure, fasting lipid profile and fasting glucose level were assessed. Receiver operating characteristics curves analysis was used to evaluate the ability of each anthropometric index to discriminate MetS cases from non-MetS cases based on the area under the curve. Overall, WC had better discriminative ability than WHR for women but did not perform significantly better than BMI in both sexes, whereas BMI was better than WHR in women only. Waist circumference was a better discriminator of MetS compared to WHR in Malay men and women. Waist circumference and BMI performed better than WHR in Chinese women, men aged 25-34 years and women aged 35-44 years. The discriminative ability of BMI and WC is better than WHR for predicting two or more non-adipose components of MetS. Therefore, either BMI or WC measurements are recommended in screening for metabolic syndrome in routine clinical practice in the effort to combat cardiovascular disease and type II diabetes mellitus. Copyright © 2015 Diabetes India. Published by Elsevier Ltd. All rights reserved.

  13. Impact of insecticides used to control Spodoptera frugiperda (J.E. Smith in corn on survival, sex ratio, and reproduction of Trichogramma pretiosum Riley offspring

    Directory of Open Access Journals (Sweden)

    Jander R Souza

    2013-06-01

    Full Text Available Corn (Zea mays L. is cultivated in large areas and considered one of the world's major cereal crops. There are several arthropod pests that can reduce its production such as the fall armyworm, Spodoptera frugiperda (J.E. Smith (Lep.: Noctuidae, which is considered to be the main pest for corn. Fall armyworm is primarily controlled by insecticides. The use of biological control agents to manage this pest is growing with an emphasis on the egg parasitoid Trichogramma pretiosum Riley (Hym.: Trichogrammatidae. Thus, the aim of this research was to evaluate the impact of the following insecticides (g ai L-1 beta-cypermethrin (0.03, chlorfenapyr (0.60, chlorpyrifos (0.96, spinosad (0.16, etofenprox (0.10, triflumuron (0.08, alfa-cypermethrin/teflubenzuron (0.0425/0.0425, and lambda-cyhalothrin/thiamethoxam (0.11/0.083 on survival, sex ratio, reproduction, and T. pretiosum offspring. Distilled water was used as a control. Commercial insecticide formulations were diluted in distilled water. Bioassays used Anagasta kuehniella eggs treated with insecticides which were afterwards exposed to parasitism. Bioassays were conducted under controlled conditions at 25 ± 2 °C, 70 ± 10% RH, and 12:12 h photoperiod. Alfa-cypermethrin/teflubenzuron, beta-cypermethrin, chlorpyrifos, chlorfenapyr, spinosad, etofenprox, and lambda-cyhalothrin/thiamethoxam reduced parasitism capacity of maternal generation females as well as the percentage of insect emergence from the F1 generation. Only triflumuron was selective for T. pretiosum and can be recommended along with this parasitoid in fall armyworm management programs in corn.

  14. Characterization of the factor VIII defect in 147 patients with sporadic hemophilia A: Family studies indicate a mutation type-dependent sex ratio of mutation frequencies

    Energy Technology Data Exchange (ETDEWEB)

    Becker, J.; Schmidt, W.; Olek, K. [Univ. of Bonn (Germany)] [and others

    1996-04-01

    The clinical manifestation of hemophilia A is caused by a wide range of different mutations. In this study the factor VIII genes of 147 severe hemophilia A patients-all exclusively from sporadic families-were screened for mutations by use of the complete panel of modern DNA techniques. The pathogenous defect could be characterized in 126 patients (85.7%). Fifty-five patients (37.4%) showed a F8A-gene inversion, 47 (32.0%) a point mutation, 14 (9.5%) a small deletion, 8 (5.4%) a large deletion, and 2 (1.4%) a small insertion. Further, four (2.7%) mutations were localized but could not be sequenced yet. No mutation could be identified in 17 patients (11.6%). Sixteen (10.9%) of the P identified mutations occurred in the B domain. Four of these were located in an adenosine nucleotide stretch at codon 1192, indicating a mutation hotspot. Somatic mosaicisms were detected in 3 (3.9%) of 76 patients` mothers, comprising 3 of 16 de novo mutations in the patients` mothers. Investigation of family relatives allowed detection of a de novo mutation in 16 of 76 two-generation and 28 of 34 three-generation families. On the basis of these data, the male:female ratio of mutation frequencies (k) was estimated as k = 3.6. By use of the quotients of mutation origin in maternal grandfather to patient`s mother or to maternal grandmother, k was directly estimated as k = 15 and k = 7.5, respectively. Considering each mutation type separately, we revealed a mutation type-specific sex ratio of mutation frequencies. Point mutations showed a 5-to-10-fold-higher and inversions a >10-fold- higher mutation rate in male germ cells, whereas deletions showed a >5-fold-higher mutation rate in female germ cells. Consequently, and in accordance with the data of other diseases like Duchenne muscular dystrophy, our results indicate that at least for X-chromosomal disorders the male:female mutation rate of a disease is determined by its proportion of the different mutation types. 68 refs., 1 fig., 5 tabs.

  15. Repeating Marx

    DEFF Research Database (Denmark)

    Fuchs, Christian; Monticelli, Lara

    2018-01-01

    This introduction sets out the context of the special issue “Karl Marx @ 200: Debating Capitalism & Perspectives for the Future of Radical Theory”, which was published on the occasion of Marx’s bicentenary on 5 May 2018. First, we give a brief overview of contemporary capitalism’s development...... and its crises. Second, we argue that it is important to repeat Marx today. Third, we reflect on lessons learned from 200 years of struggles for alternatives to capitalism. Fourth, we give an overview of the contributions in this special issue. Taken together, the contributions in this special issue show...... that Marx’s theory and politics remain key inspirations for understanding exploitation and domination in 21st-century society and for struggles that aim to overcome these phenomena and establishing a just and fair society. We need to repeat Marx today....

  16. Deployment Repeatability

    Science.gov (United States)

    2016-08-31

    large cohort of trials to spot unusual cases. However, deployment repeatability is inherently a nonlinear phenomenon, which makes modeling difficult...and GEMS tip position were both tracked during ground testing by a laser target tracking system. Earlier SAILMAST testing in 2005 [8] used...recalls the strategy used by SRTM, where a constellation of lights was installed at the tip of the boom and a modified star tracker was used to track tip

  17. Safe sex

    Science.gov (United States)

    ... sex; Sexually transmitted - safe sex; GC - safe sex; Gonorrhea - safe sex; Herpes - safe sex; HIV - safe sex; ... contact. STIs include: Chlamydia Genital herpes Genital warts Gonorrhea Hepatitis HIV HPV Syphilis STIs are also called ...

  18. Adult sex ratio effects on male survivorship of Drosophila melanogaster Meigen (Diptera, Drosophilidae Efeito da razão sexual de adultos na curva de sobrevivência de machos de Drosophila melanogaster Meigen (Diptera, Drosophilidae

    Directory of Open Access Journals (Sweden)

    Marcelo Costa

    2010-01-01

    Full Text Available The behavioral biology has a central role in evolutionary biology mainly because the antagonistic relations that occur in the sexual reproduction. One involves the effect of reproduction on the future life expectation. In this scenario, changes in male operational sex ratio could lead to an increase in mortality due to costs associated with excessive courtship and mating displays. Thus, this work experimentally altered the male sex ratio of Drosophila melanogaster Meigen, 1830, to determine its impact on mortality. The results indicated that mortality increases as the sex ratio changes, including modifications in the survivorship curve type and in the curve concavity, measured by entropy.A biologia comportamental tem um papel central na biologia evolutiva principalmente pelas relações antagônicas que ocorrem na reprodução sexuada. Uma destas relações envolve o efeito da reprodução sobre a expectativa de vida futura. Neste cenário, alterações na razão sexual operacional de machos podem levar a um aumento na mortalidade por causa dos custos associados com o excesso de displays de corte e cópulas. Neste sentido este trabalho alterou experimentalmente a razão sexual em machos de Drosophila melanogaster Meigen, 1830, para determinar os efeitos em termos de mortalidade. Os resultados indicam que a mortalidade aumenta a medida que a razão sexual se enviesa incluindo alterações no tipo de curva de sobrevivência e da concavidade da curva, medida pela entropia.

  19. Weight-length Relationships, Gonadosomatic Indeces, Sex Ratios and Relative Weight of the Omani-Indian Oil sardine, Sardinella longiceps (Valenciennes1847) from Al-Seeb Area; Sultanate of Oman

    OpenAIRE

    Al-Jufaili Saud

    2011-01-01

    This study presents the weight-length relationship and spawning period of the Omani Indian Oil sardine Sardinella longiceps (Valenciennes 1847) which inhabits the near shore zone along the Omani coast. A total of 1744 specimens were collected between January 1997 to February 1998 from Al-Seeb; a suburban area situated by the sea in Muscat, Oman. Samples were obtained on a monthly basis from beach seine and gillnet catches. The female to male sex ratio was obtained to be 0.6. The monthly varia...

  20. Huntingtin gene repeat size variations affect risk of lifetime depression.

    Science.gov (United States)

    Gardiner, Sarah L; van Belzen, Martine J; Boogaard, Merel W; van Roon-Mom, Willeke M C; Rozing, Maarten P; van Hemert, Albert M; Smit, Johannes H; Beekman, Aartjan T F; van Grootheest, Gerard; Schoevers, Robert A; Oude Voshaar, Richard C; Roos, Raymund A C; Comijs, Hannie C; Penninx, Brenda W J H; van der Mast, Roos C; Aziz, N Ahmad

    2017-12-11

    Huntington disease (HD) is a severe neuropsychiatric disorder caused by a cytosine-adenine-guanine (CAG) repeat expansion in the HTT gene. Although HD is frequently complicated by depression, it is still unknown to what extent common HTT CAG repeat size variations in the normal range could affect depression risk in the general population. Using binary logistic regression, we assessed the association between HTT CAG repeat size and depression risk in two well-characterized Dutch cohorts─the Netherlands Study of Depression and Anxiety and the Netherlands Study of Depression in Older Persons─including 2165 depressed and 1058 non-depressed persons. In both cohorts, separately as well as combined, there was a significant non-linear association between the risk of lifetime depression and HTT CAG repeat size in which both relatively short and relatively large alleles were associated with an increased risk of depression (β = -0.292 and β = 0.006 for the linear and the quadratic term, respectively; both P < 0.01 after adjustment for the effects of sex, age, and education level). The odds of lifetime depression were lowest in persons with a HTT CAG repeat size of 21 (odds ratio: 0.71, 95% confidence interval: 0.52 to 0.98) compared to the average odds in the total cohort. In conclusion, lifetime depression risk was higher with both relatively short and relatively large HTT CAG repeat sizes in the normal range. Our study provides important proof-of-principle that repeat polymorphisms can act as hitherto unappreciated but complex genetic modifiers of depression.

  1. Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington's Disease Knock-In Mice.

    Science.gov (United States)

    Neto, João Luís; Lee, Jong-Min; Afridi, Ali; Gillis, Tammy; Guide, Jolene R; Dempsey, Stephani; Lager, Brenda; Alonso, Isabel; Wheeler, Vanessa C; Pinto, Ricardo Mouro

    2017-02-01

    Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in exon 1 of the HTT gene. Longer repeat sizes are associated with increased disease penetrance and earlier ages of onset. Intergenerationally unstable transmissions are common in HD families, partly underlying the genetic anticipation seen in this disorder. HD CAG knock-in mouse models also exhibit a propensity for intergenerational repeat size changes. In this work, we examine intergenerational instability of the CAG repeat in over 20,000 transmissions in the largest HD knock-in mouse model breeding datasets reported to date. We confirmed previous observations that parental sex drives the relative ratio of expansions and contractions. The large datasets further allowed us to distinguish effects of paternal CAG repeat length on the magnitude and frequency of expansions and contractions, as well as the identification of large repeat size jumps in the knock-in models. Distinct degrees of intergenerational instability were observed between knock-in mice of six background strains, indicating the occurrence of trans-acting genetic modifiers. We also found that lines harboring a neomycin resistance cassette upstream of Htt showed reduced expansion frequency, indicative of a contributing role for sequences in cis, with the expanded repeat as modifiers of intergenerational instability. These results provide a basis for further understanding of the mechanisms underlying intergenerational repeat instability. Copyright © 2017 by the Genetics Society of America.

  2. EVALUATION OF LOWER FACE HEIGHTS AND RATIOS ACCORDING TO SEX. 213\tEvaluación de las alturas y proporciones de la parte inferior de la cara en relación al sexo

    Directory of Open Access Journals (Sweden)

    Ayla Kurkcuoglu

    2016-03-01

    . This study was conducted with the aim of determining lower face height ratios in Baskent University students and evidencing possible sex-related differences. The study was performed on 95 female and 101 male, aged 18-25, atotal of 196 Turkish volunteer students. Lateral photogrammetric images were acquired by the same person for all subjects in natural head position, with their mouth closed in normal posture. The images were transferred to a computing environment. The determination of six anthropometric points in the vertical plane, the measurement of their relative distances and the calculation of seven ratios were done by the same person on all photographs. A significant difference according to the subjects' sex was identified in all seven parameters measured among the anthropometric landmarks. When the lower face height ratios were evaluated the largest one was the upper vermilion height/lower vermilion height ratio both in males and females,and the smallest one was the upper vermilion height/upper lip height ratio in female subjects and the upper lip height/height of the lower face  in males. We hypothesize that the knowledge of certain facial ratios and their differences according to sex and race may serve as a guide for therapy planning in different surgical interventions, orthodontic follow-up and personal identification. 

  3. Biometrics, sex ratio and sexual dimorphism of Trachemys dorbigni (Duméril & Bibron 1835 (Testudines, Emydidae from an artificial reservoir in the municipality of São Gabriel, Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Alex Bager

    2012-09-01

    Full Text Available This work describes the population structure of Trachemys dorbigni from an artificial reservoir (30º20’16,03”S, 54º15’46,68”W in the municipality of São Gabriel, Rio Grande do Sul, Brazil. From March 2009 to February 2010, forty-four individuals were collected: 34 females, seven males, and three juveniles. The sex ratio was 4.85 females: 1 male (1:1. The mean carapace length of the adults was 190.50 ± 22.81mm (N=41 and the mean body mass was 1.210 ± 420g (N=37. Carapace length averaged 179.10 ± 18.60mm (N =7 for males and 192.90 ± 23.10mm (N=34 for females. Females were significantly larger than males for six of the eleven measurements made and smaller for one measurement, which was the distance from the base of tail to the cloacae. The discriminant analysis revealed significant morphological differences between males and females (P<0,05; F3.37=21.02; Wilks’ lambda=0.36, indicating carapace and plastron terminal distance, curvilinear carapace length and distance from the base of tail to the cloacae as important variables for sexing this species.

  4. Sex ratios in the most-selective elite US undergraduate colleges and universities are consistent with the hypothesis that modern educational systems increasingly select for conscientious personality compared with intelligence.

    Science.gov (United States)

    Charlton, Bruce G

    2009-08-01

    The main predictors of examination results and educational achievement in modern societies are intelligence (IQ - or general factor 'g' intelligence) and the personality trait termed 'Conscientiousness' (C). I have previously argued that increased use of continuous assessment (e.g. course work rather than timed and supervised examinations) and increased duration of the educational process implies that modern educational systems have become increasingly selective for the personality trait of Conscientiousness and consequently less selective for IQ. I have tested this prediction (in a preliminary fashion) by looking at the sex ratios in the most selective elite US universities. My two main assumptions are: (1) that a greater proportion of individuals with very high intelligence are men than women, and (2) that women are more conscientious than men. To estimate the proportion of men and women expected at highly-selective schools, I performed demonstration calculations based on three plausible estimates of male and female IQ averages and standard deviations. The expected percentage of men at elite undergraduate colleges (selecting students with IQ above 130 - i.e. in the top 2% of the population) were 66%, 61% and 74%. When these estimates were compared with the sex ratios at 33 elite colleges and universities, only two technical institutes had more than 60% men. Elite US colleges and universities therefore seem to be selecting primarily on the basis of something other than IQ - probably conscientiousness. There is a 'missing population' of very high IQ men who are not being admitted to the most selective and prestigious undergraduate schools, probably because their high school educational qualifications and evaluations are too low. This analysis is therefore consistent with the hypothesis that modern educational systems tend to select more strongly for Conscientiousness than for IQ. The implication is that modern undergraduates at the most-selective US schools are not

  5. Efeito de diferentes meios de cultivo no desenvolvimento e proporção do sexo de embriões bovinos produzidos in vitro Effect of different culture media on development and sex ratio of bovine embryos fertilized in vitro

    Directory of Open Access Journals (Sweden)

    S.G.T. Gilardi

    2004-10-01

    Full Text Available Avaliou-se o efeito da suplementação de meios de cultivo sobre o desenvolvimento e proporção do sexo de embriões bovinos fertilizados in vitro. Complexos cumulus-oócitos obtidos de ovários de matadouro foram maturados e fertilizados in vitro. Os zigotos (n= 484 foram distribuídos aleatoriamente em meio CR2aa, contendo soro fetal bovino (SFB (T1, albumina sérica bovina (BSA (T2 ou BSA mais insulina:transferrina:selênio e vitaminas (BSA+ (T3, no cultivo embrionário in vitro, a uma atmosfera de 5% CO2 a 38,8ºC em ar. A taxa de clivagem foi observada 72-76 horas pós-fertilização (PF e a taxa de blastocistos com sete e oito dias PF. Os blastocistos (n= 63 foram sexados pela técnica de reação em cadeia de polimerase. A taxa de clivagem em T2 foi maior (P0,05 entre T2 e T3, porém menor (P0,05 entre os tratamentos. O T1 influenciou o desenvolvimento de blastocistos, mas não teve efeito sobre a proporção do sexo.The effect of culture media on the development and on the sex ratio of bovine embryos fertilized in vitro was studied. Cumulus oocyte-complexes from slaughterhouse ovaries were matured and fertilized in vitro. Zygotes (n= 484 were randomly allotted to different culture media and cultured with their cumulus cells in CR2aa medium and an atmosphere of 5% CO2 in air at 38.8ºC. The fetal calf serum (FCS, bovine seric albumin (BSA or BSA plus insulin:transferrin:selenium and vitamins (BSA+ supplementation effect on embryo culture was evaluated. Cleavage rate was assessed at 72-76h post-fertilization (PF and blastocyst rate on days 7 and 8 PF. The blastocysts (n= 63 were also sexed using polymerase chain reaction. Cleavage rate for BSA medium supplemented was higher (P0.05, but lower (P<0.01 than FCS. Culture medium FCS supplemented affected blastocyst development but not the sex ratio.

  6. O sexo masculino vulnerável: razão de masculinidade entre os óbitos fetais brasileiros The vulnerable male, or the sex ratio among fetal deaths in Brazil

    Directory of Open Access Journals (Sweden)

    Alexandre Dias Porto Chiavegatto Filho

    2012-04-01

    Full Text Available Alguns estudos apontam para a existência de vulnerabilidades biológicas inatas masculinas, especialmente no período perinatal. Foi realizada uma análise transversal da mortalidade fetal brasileira segundo sexo, entre 2000 e 2009 (inclusive, conforme características maternas (idade, escolaridade e duração da gestação, utilizando-se dados disponibilizados pelos sistema DATASUS do Ministério da Saúde. Todos os óbitos fetais do período foram incluídos na análise, excetuando-se os casos em que o sexo do feto não foi declarado. A razão de masculinidade (RM encontrada para os óbitos fetais foi de 1,188. As categorias mais relacionadas com maior risco (idade entre 10 e 14 anos, nenhuma escolaridade e gestação com menos de 22 semanas apresentaram maior RM, sendo esses valores, em todos os casos, estatisticamente maiores do que os observados nas outras categorias analisadas (p Some studies indicate the existence of innate male vulnerabilities, especially during the perinatal period. The current study is a cross-sectional analysis of fetal mortality in Brazil according to sex from 2000 to 2009, stratified by maternal characteristics (age, schooling, and gestational age, using Ministry of Health data (DATASUS. The analysis included all fetal deaths from 2000 to 2009, except when the sex of the fetus was not recorded. The male/female sex ratio (SR for all fetal deaths was 1.188. Analysis of maternal characteristics showed that the SR was statistically higher (p < 0.01 in mothers that were younger (10-14 years, had no formal schooling, and with gestational age < 22 weeks. The study showed a statistically higher-than-expected SR (p < 0.01 for 13 underlying causes of death and a lower SR for two others. The results suggest a potential innate male vulnerability.

  7. Sexing young snowy owls

    Science.gov (United States)

    Seidensticker, M.T.; Holt, D.W.; Detienne, J.; Talbot, S.; Gray, K.

    2011-01-01

    We predicted sex of 140 Snowy Owl (Bubo scandiacus) nestlings out of 34 nests at our Barrow, Alaska, study area to develop a technique for sexing these owls in the field. We primarily sexed young, flightless owls (3844 d old) by quantifying plumage markings on the remiges and tail, predicting sex, and collecting blood samples to test our field predictions using molecular sexing techniques. We categorized and quantified three different plumage markings: two types of bars (defined as markings that touch the rachis) and spots (defined as markings that do not touch the rachis). We predicted sex in the field assuming that males had more spots than bars and females more bars than spots on the remiges and rectrices. Molecular data indicated that we correctly sexed 100% of the nestlings. We modeled the data using random forests and classification trees. Both models indicated that the number and type of markings on the secondary feathers were the most important in classifying nestling sex. The statistical models verified our initial qualitative prediction that males have more spots than bars and females more bars than spots on flight feathers P6P10 for both wings and tail feathers T1 and T2. This study provides researchers with an easily replicable and highly accurate method for sexing young Snowy Owls in the field, which should aid further studies of sex-ratios and sex-related variation in behavior and growth of this circumpolar owl species. ?? 2011 The Raptor Research Foundation, Inc.

  8. Sex Therapy

    Science.gov (United States)

    Sex therapy Overview Sex therapy is a type of psychotherapy — a general term for treating mental health problems by talking with a mental health professional. Through sex therapy, you can address concerns about sexual function, ...

  9. Golden Ratio

    Indian Academy of Sciences (India)

    Our attraction to another body increases if the body is symmetricaland in proportion. If a face or a structure is in proportion,we are more likely to notice it and find it beautiful.The universal ratio of beauty is the 'Golden Ratio', found inmany structures. This ratio comes from Fibonacci numbers.In this article, we explore this ...

  10. Golden Ratio

    Indian Academy of Sciences (India)

    Keywords. Fibonacci numbers, golden ratio, Sanskrit prosody, solar panel. Abstract. Our attraction to another body increases if the body is symmetricaland in proportion. If a face or a structure is in proportion,we are more likely to notice it and find it beautiful.The universal ratio of beauty is the 'Golden Ratio', found inmany ...

  11. Golden Ratio

    Indian Academy of Sciences (India)

    Our attraction to another body increases if the body is sym- metrical and in proportion. If a face or a structure is in pro- portion, we are more likely to notice it and find it beautiful. The universal ratio of beauty is the 'Golden Ratio', found in many structures. This ratio comes from Fibonacci numbers. In this article, we explore this ...

  12. Battle of the Sexes

    NARCIS (Netherlands)

    Bulte, E.H.; Tu, Q.; List, J.

    2015-01-01

    A vibrant literature has emerged that explores the economic implications of the sex ratio (the ratio of men to women in the population), including changes in fertility rates, educational outcomes, labor supply, and household purchases. Previous empirical efforts, however, have paid less attention to

  13. Revisiting the TALE repeat.

    Science.gov (United States)

    Deng, Dong; Yan, Chuangye; Wu, Jianping; Pan, Xiaojing; Yan, Nieng

    2014-04-01

    Transcription activator-like (TAL) effectors specifically bind to double stranded (ds) DNA through a central domain of tandem repeats. Each TAL effector (TALE) repeat comprises 33-35 amino acids and recognizes one specific DNA base through a highly variable residue at a fixed position in the repeat. Structural studies have revealed the molecular basis of DNA recognition by TALE repeats. Examination of the overall structure reveals that the basic building block of TALE protein, namely a helical hairpin, is one-helix shifted from the previously defined TALE motif. Here we wish to suggest a structure-based re-demarcation of the TALE repeat which starts with the residues that bind to the DNA backbone phosphate and concludes with the base-recognition hyper-variable residue. This new numbering system is consistent with the α-solenoid superfamily to which TALE belongs, and reflects the structural integrity of TAL effectors. In addition, it confers integral number of TALE repeats that matches the number of bound DNA bases. We then present fifteen crystal structures of engineered dHax3 variants in complex with target DNA molecules, which elucidate the structural basis for the recognition of bases adenine (A) and guanine (G) by reported or uncharacterized TALE codes. Finally, we analyzed the sequence-structure correlation of the amino acid residues within a TALE repeat. The structural analyses reported here may advance the mechanistic understanding of TALE proteins and facilitate the design of TALEN with improved affinity and specificity.

  14. Reconfigurable multiport EPON repeater

    Science.gov (United States)

    Oishi, Masayuki; Inohara, Ryo; Agata, Akira; Horiuchi, Yukio

    2009-11-01

    An extended reach EPON repeater is one of the solutions to effectively expand FTTH service areas. In this paper, we propose a reconfigurable multi-port EPON repeater for effective accommodation of multiple ODNs with a single OLT line card. The proposed repeater, which has multi-ports in both OLT and ODN sides, consists of TRs, BTRs with the CDR function and a reconfigurable electrical matrix switch, can accommodate multiple ODNs to a single OLT line card by controlling the connection of the matrix switch. Although conventional EPON repeaters require full OLT line cards to accommodate subscribers from the initial installation stage, the proposed repeater can dramatically reduce the number of required line cards especially when the number of subscribers is less than a half of the maximum registerable users per OLT. Numerical calculation results show that the extended reach EPON system with the proposed EPON repeater can save 17.5% of the initial installation cost compared with a conventional repeater, and can be less expensive than conventional systems up to the maximum subscribers especially when the percentage of ODNs in lightly-populated areas is higher.

  15. Quantum repeated games revisited

    International Nuclear Information System (INIS)

    Frąckiewicz, Piotr

    2012-01-01

    We present a scheme for playing quantum repeated 2 × 2 games based on Marinatto and Weber’s approach to quantum games. As a potential application, we study the twice repeated Prisoner’s Dilemma game. We show that results not available in the classical game can be obtained when the game is played in the quantum way. Before we present our idea, we comment on the previous scheme of playing quantum repeated games proposed by Iqbal and Toor. We point out the drawbacks that make their results unacceptable. (paper)

  16. Learning With Repeated-Game Strategies

    Directory of Open Access Journals (Sweden)

    Christos A. Ioannou

    2014-07-01

    Full Text Available We use the self-tuning Experience Weighted Attraction model with repeated-game strategies as a computer testbed to examine the relative frequency, speed of convergence and progression of a set of repeated-game strategies in four symmetric 2x2 games: Prisoner's Dilemma, Battle of the Sexes, Stag-Hunt, and Chicken. In the Prisoner's Dilemma game, we fi□nd that the strategy with the most occurrences is the Grim-Trigger. In the Battle of the Sexes game, a cooperative pair that alternates between the two pure-strategy Nash equilibria emerges as the one with the most occurrences. In the Stag-Hunt and Chicken games, the Win-Stay, Lose-Shift and Grim-Trigger strategies are the ones with the most occurrences. Overall, the pairs that converged quickly ended up at the cooperative outcomes, whereas the ones that were extremely slow to reach convergence ended up at non-cooperative outcomes.

  17. Sex Headaches

    Science.gov (United States)

    Sex headaches Overview Sex headaches are brought on by sexual activity — especially an orgasm. You may notice a dull ache in your head ... severe headache just before or during orgasm. Most sex headaches are nothing to worry about. But some ...

  18. Sex selection: treating different cases differently.

    Science.gov (United States)

    Dickens, B M; Serour, G I; Cook, R J; Qiu, R-Z

    2005-08-01

    This paper contrasts ethical approaches to sex selection in countries where discrimination against women is pervasive, resulting in selection against girl children, and in countries where there is less general discrimination and couples do not prefer children of either sex. National sex ratio imbalances where discrimination against women is common have resulted in laws and policies, such as in India and China, to deter and prevent sex selection. Birth ratios of children can be affected by techniques of prenatal sex determination and abortion, preconception sex selection and discarding disfavored embryos, and prefertilization sperm sorting, when disfavored sperm remain unused. Incentives for son preference are reviewed, and laws and policies to prevent sex selection are explained. The elimination of social, economic and other discrimination against women is urged to redress sex selection against girl children. Where there is no general selection against girl children, sex selection can be allowed to assist families that want children of both sexes.

  19. The Pentapeptide Repeat Proteins

    OpenAIRE

    Vetting, Matthew W.; Hegde, Subray S.; Fajardo, J. Eduardo; Fiser, Andras; Roderick, Steven L.; Takiff, Howard E.; Blanchard, John S.

    2006-01-01

    The Pentapeptide Repeat Protein (PRP) family has over 500 members in the prokaryotic and eukaryotic kingdoms. These proteins are composed of, or contain domains composed of, tandemly repeated amino acid sequences with a consensus sequence of [S,T,A,V][D,N][L,F]-[S,T,R][G]. The biochemical function of the vast majority of PRP family members is unknown. The three-dimensional structure of the first member of the PRP family was determined for the fluoroquinolone resistance protein (MfpA) from Myc...

  20. Repeated Causal Decision Making

    Science.gov (United States)

    Hagmayer, York; Meder, Bjorn

    2013-01-01

    Many of our decisions refer to actions that have a causal impact on the external environment. Such actions may not only allow for the mere learning of expected values or utilities but also for acquiring knowledge about the causal structure of our world. We used a repeated decision-making paradigm to examine what kind of knowledge people acquire in…

  1. simple sequence repeat (SSR)

    African Journals Online (AJOL)

    In the present study, 78 mapped simple sequence repeat (SSR) markers representing 11 linkage groups of adzuki bean were evaluated for transferability to mungbean and related Vigna spp. 41 markers amplified characteristic bands in at least one Vigna species. The transferability percentage across the genotypes ranged ...

  2. Repeat polymorphisms in ESR2 and AR and colorectal cancer risk and prognosis: results from a German population-based case-control study.

    Science.gov (United States)

    Rudolph, Anja; Shi, Hong; Försti, Asta; Hoffmeister, Michael; Sainz, Juan; Jansen, Lina; Hemminki, Kari; Brenner, Hermann; Chang-Claude, Jenny

    2014-11-07

    Evidence has accumulated which suggests that sex steroids influence colorectal cancer development and progression. We therefore assessed the association of repeat polymorphisms in the estrogen receptor β gene (ESR2) and the androgen receptor gene (AR) with colorectal cancer risk and prognosis. The ESR2 CA and AR CAG repeat polymorphisms were genotyped in 1798 cases (746 female, 1052 male) and 1810 controls (732 female, 1078 male), matched for sex, age and county of residence. Colorectal cancer risk associations overall and specific for gender were evaluated using multivariate logistic regression models adjusted for sex, county of residence and age. Associations with overall and disease-specific survival were evaluated using Cox proportional hazard models adjusted for established prognostic factors (diagnosis of other cancer after colorectal cancer diagnosis, detection by screening, treatment with adjuvant chemotherapy, tumour extent, nodal status, distant metastasis, body mass index, age at diagnosis and year of diagnosis) and stratified for grade of differentiation. Heterogeneity in gender specific associations was assessed by comparing models with and without a multiplicative interaction term by means of a likelihood ratio test. The average number of ESR2 CA repeats was associated with a small 5% increase in colorectal cancer risk (OR = 1.05, 95% CI 1.01-1.10) without significant heterogeneity according to gender or tumoural ESR2 expression. We found no indication for an association between the AR CAG repeat polymorphisms and risk of colorectal cancer. The ESR2 CA and AR CAG repeat polymorphisms were not associated with overall survival or disease specific survival after colorectal cancer diagnosis. Higher numbers of ESR2 CA repeats are potentially associated with a small increase in colorectal cancer risk. Our study does not support an association between colorectal cancer prognosis and the investigated repeat polymorphisms.

  3. Creating Sex

    DEFF Research Database (Denmark)

    Cahana, Jonathan

    2016-01-01

    Thomas Laqueur’s influential yet controversial study Making Sex has, in many ways, revolutionized our understanding of sexuality in antiquity. Yet, most of Laqueur’s critics and supporters stressed the one-sex body, while the crux of his argument is the primacy of gender. Moreover, a systematic...

  4. Sex determination

    Indian Academy of Sciences (India)

    The sex-determining system differs considerably among organisms. Even among insect species, the genetic system for sex-determination is highly diversified. In Drosophila melanogaster, somatic sexual differentiation is regulated by a well characterized genetic hierarchy X : A > Sxl > tra/tra2 > dsx and fru. This cascade ...

  5. Hybrid FRC under repeated loading

    International Nuclear Information System (INIS)

    Komlos, K.; Babal, B.; Nuernbergerova, T.

    1993-01-01

    Fibre reinforced concretes (FRC) containing several volume fractions in different ratios of two types of fibres - polypropylene and steel, were tested under repeated loading. Mechanical properties of specimens - cubes 150/150/150 mm (for compressive strength), prisms 100/100/400 (for flexural strength), short cylinders 150/60 mm (for impact strength) have been experimentally investigated before and after cyclic loading at the age of 28 days curing time. Mix proportions were designed after DIN 1045 with max. aggregate size 8 mm and grading curve B 8. Portland Cement PC 400 in the amount of 450 kg. m -3 was applied and W/C ratio 0.55. Workability of mixes was measured by Vebe method and regulated by plasticizing admixture Ligoplast Na. Maximum hybrid fibre volume fraction (polypropylene + steel) was 1.0%. Dynamic forces generated in Schenck testing machine with frequency 16 Hz had sinusoidal wave form varying between 0.7 and 0.1 of static mechanical characteristics. The number of cycles in all tests was 10 5 . The residual MOR at static four point bending test and working diagram force-deflection was carried out as well. The impact properties after repeated loading in compression were tested by means of falling weight test. Relationships between composition of fibre composites with different combination of polypropylene (0.2, 0.3, 0.5% by volume) and steel (0.5, 0.7, and 0.8% by volume) fibre content were obtained and technological properties of mixes as well. (author)

  6. Neutrophil Lymphocyte Ratio Predicts Postoperative Pain after ...

    African Journals Online (AJOL)

    2018-02-07

    Feb 7, 2018 ... between preoperatively measured neutrophil-lymphocyte ratio (NLR) – as an inflammation ... analgesic (tenoxicam – as the first drug of choice, paracetamol, tramadol, or pethidine) usage ... fracture fixation). Age, sex, type of ...

  7. Oral sex.

    Science.gov (United States)

    1996-04-05

    The Gay and Lesbian Medical Association urges HIV prevention specialists to regard male-to-male oral-genital sex as a low-risk activity and concentrate instead on the danger of unprotected anal intercourse. According to the association, the confusion and mixed messages surrounding oral sex are harming efforts to encourage gay men to make rational choices about truly risky behavior. The recommendations appear in the association's position paper issued March 19, 1996.

  8. Why Sex?

    DEFF Research Database (Denmark)

    Nielsen, Rasmus

    2006-01-01

    It is assumed that most organisms have sex because the resulting genetic recombination allows Darwinian selection to work better. It is now shown that in water fleas, recombination does lead to fewer deleterious mutations.......It is assumed that most organisms have sex because the resulting genetic recombination allows Darwinian selection to work better. It is now shown that in water fleas, recombination does lead to fewer deleterious mutations....

  9. Autosomal origin of sex chromosome in a polyploid plant

    Science.gov (United States)

    While theory on sex chromosome evolution is well developed, evidence of the early stages of this process remains elusive, in part because this process unfolded in many animals so long ago. The relatively recent and repeated evolution of separate sexes (dioecy) and sex chromosomes in plants, however,...

  10. Sex ratio and dynamic behavior in populations of the exotic blowfly Chrysomya albiceps (Diptera, Calliphoridae Razão sexual e comportamento dinâmico em populações da espécie de mosca varejeira exótica Chrysomya albiceps (Diptera, Calliphoridae

    Directory of Open Access Journals (Sweden)

    H. Serra

    2007-05-01

    Full Text Available Sex ratio is an essential component of life history to be considered in population growth. Chrysomya albiceps is a blowfly species with a naturally biased sex ratio. In this study, we evaluated the impact of changes in sex ratio on the dynamic behavior of C. albiceps using a density-dependent mathematical model that incorporated demographic parameters such as survival and fecundity. These parameters were obtained by exponential regression, with survival and fecundity being estimated experimentally as a function of larval density. Bifurcation diagram of the results indicated the evolution of stable equilibrium points as a function of sex ratio. A continually increasing sex ratio yielded a hierarchy of bifurcating stable equilibrium points that evolved into a chaotic regime. The demographic parameters obtained by exponential regression were also changed to maximum and minimum values in order to analyze their influence on dynamic behavior with sex ratio being considered as an independent variable. Bifurcations with periodicity windows between chaos regimes were also found.A razão sexual é um componente essencial da biologia de organismos a ser considerado em crescimento populacional. Chrysomya albiceps é uma espécie de mosca varejeira que exibe um desvio na razão sexual em relação à proporção 1:1. Neste estudo avaliamos o impacto de alterações na razão sexual sobre o comportamento dinâmico de C. albiceps utilizando um modelo matemático dependente da densidade que incorpora parâmetros demográficos como sobrevivência e fecundidade. Os parâmetros foram obtidos por regressão exponencial, com sobrevivência e fecundidade sendo estimadas experimentalmente em função da densidade larval. O diagrama de bifurcação gerado pelos resultados indicou a evolução de pontos de equilíbrio estável em função da razão sexual. A sucessão contínua dos valores da razão sexual resultou em uma hierarquia de pontos de equilíbrio est

  11. Repeatability of Cryogenic Multilayer Insulation

    Science.gov (United States)

    Johnson, W. L.; Vanderlaan, M.; Wood, J. J.; Rhys, N. O.; Guo, W.; Van Sciver, S.; Chato, D. J.

    2017-12-01

    Due to the variety of requirements across aerospace platforms, and one off projects, the repeatability of cryogenic multilayer insulation (MLI) has never been fully established. The objective of this test program is to provide a more basic understanding of the thermal performance repeatability of MLI systems that are applicable to large scale tanks. There are several different types of repeatability that can be accounted for: these include repeatability between identical blankets, repeatability of installation of the same blanket, and repeatability of a test apparatus. The focus of the work in this report is on the first two types of repeatability. Statistically, repeatability can mean many different things. In simplest form, it refers to the range of performance that a population exhibits and the average of the population. However, as more and more identical components are made (i.e. the population of concern grows), the simple range morphs into a standard deviation from an average performance. Initial repeatability testing on MLI blankets has been completed at Florida State University. Repeatability of five Glenn Research Center (GRC) provided coupons with 25 layers was shown to be +/- 8.4% whereas repeatability of repeatedly installing a single coupon was shown to be +/- 8.0%. A second group of 10 coupons has been fabricated by Yetispace and tested by Florida State University, the repeatability between coupons has been shown to be +/- 15-25%. Based on detailed statistical analysis, the data has been shown to be statistically significant.

  12. Repeat Customer Success in Extension

    Science.gov (United States)

    Bess, Melissa M.; Traub, Sarah M.

    2013-01-01

    Four multi-session research-based programs were offered by two Extension specialist in one rural Missouri county. Eleven participants who came to multiple Extension programs could be called "repeat customers." Based on the total number of participants for all four programs, 25% could be deemed as repeat customers. Repeat customers had…

  13. 78 FR 65594 - Vehicular Repeaters

    Science.gov (United States)

    2013-11-01

    ... coordinators estimate the effect on coordination fees? Does the supposed benefit that mobile repeater stations... allow the licensing and operation of vehicular repeater systems and other mobile repeaters by public... email: [email protected] or phone: 202-418- 0530 or TTY: 202-418-0432. For detailed instructions for...

  14. Stress and sex: does cortisol mediate sex change in fish?

    Science.gov (United States)

    Goikoetxea, Alexander; Todd, Erica V; Gemmell, Neil J

    2017-12-01

    Cortisol is the main glucocorticoid (GC) in fish and the hormone most directly associated with stress. Recent research suggests that this hormone may act as a key factor linking social environmental stimuli and the onset of sex change by initiating a shift in steroidogenesis from estrogens to androgens. For many teleost fish, sex change occurs as a usual part of the life cycle. Changing sex is known to enhance the lifetime reproductive success of these fish and the modifications involved (behavioral, gonadal and morphological) are well studied. However, the exact mechanism behind the transduction of the environmental signals into the molecular cascade that underlies this singular process remains largely unknown. We here synthesize current knowledge regarding the role of cortisol in teleost sex change with a focus on two well-described transformations: temperature-induced masculinization and socially regulated sex change. Three non-mutually exclusive pathways are considered when describing the potential role of cortisol in mediating teleost sex change: cross-talk between GC and androgen pathways, inhibition of aromatase expression and upregulation of amh (the gene encoding anti-Müllerian hormone). We anticipate that understanding the role of cortisol in the initial stages of sex change will further improve our understanding of sex determination and differentiation across vertebrates, and may lead to new tools to control fish sex ratios in aquaculture. © 2017 Society for Reproduction and Fertility.

  15. Coevolution of parental investment and sexually selected traits drives sex-role divergence.

    Science.gov (United States)

    Fromhage, Lutz; Jennions, Michael D

    2016-08-18

    Sex-role evolution theory attempts to explain the origin and direction of male-female differences. A fundamental question is why anisogamy, the difference in gamete size that defines the sexes, has repeatedly led to large differences in subsequent parental care. Here we construct models to confirm predictions that individuals benefit less from caring when they face stronger sexual selection and/or lower certainty of parentage. However, we overturn the widely cited claim that a negative feedback between the operational sex ratio and the opportunity cost of care selects for egalitarian sex roles. We further argue that our model does not predict any effect of the adult sex ratio (ASR) that is independent of the source of ASR variation. Finally, to increase realism and unify earlier models, we allow for coevolution between parental investment and investment in sexually selected traits. Our model confirms that small initial differences in parental investment tend to increase due to positive evolutionary feedback, formally supporting long-standing, but unsubstantiated, verbal arguments.

  16. Testosterone Administration Moderates Effect of Social Environment on Trust in Women Depending on Second-to-Fourth Digit Ratio.

    Science.gov (United States)

    Buskens, Vincent; Raub, Werner; van Miltenburg, Nynke; Montoya, Estrella R; van Honk, Jack

    2016-06-10

    Animal research has established that effects of hormones on social behaviour depend on characteristics of both individual and environment. Insight from research on humans into this interdependence is limited, though. Specifically, hardly any prior testosterone experiments in humans scrutinized the interdependency of testosterone with the social environment. Nonetheless, recent testosterone administration studies in humans repeatedly show that a proxy for individuals' prenatal testosterone-to-estradiol ratio, second-to-fourth digit-ratio (2D:4D ratio), influences effects of testosterone administration on human social behaviour. Here, we systematically vary the characteristics of the social environment and show that, depending on prenatal sex hormone priming, testosterone administration in women moderates the effect of the social environment on trust. We use the economic trust game and compare one-shot games modelling trust problems in relations between strangers with repeated games modelling trust problems in ongoing relations between partners. As expected, subjects are more trustful in repeated than in one-shot games. In subjects prenatally relatively highly primed by testosterone, however, this effect disappears after testosterone administration. We argue that impairments in cognitive empathy may reduce the repeated game effect on trust after testosterone administration in subjects with relatively high prenatal testosterone exposure and propose a neurobiological explanation for this effect.

  17. Repeated causal decision making.

    Science.gov (United States)

    Hagmayer, York; Meder, Björn

    2013-01-01

    Many of our decisions refer to actions that have a causal impact on the external environment. Such actions may not only allow for the mere learning of expected values or utilities but also for acquiring knowledge about the causal structure of our world. We used a repeated decision-making paradigm to examine what kind of knowledge people acquire in such situations and how they use their knowledge to adapt to changes in the decision context. Our studies show that decision makers' behavior is strongly contingent on their causal beliefs and that people exploit their causal knowledge to assess the consequences of changes in the decision problem. A high consistency between hypotheses about causal structure, causally expected values, and actual choices was observed. The experiments show that (a) existing causal hypotheses guide the interpretation of decision feedback, (b) consequences of decisions are used to revise existing causal beliefs, and (c) decision makers use the experienced feedback to induce a causal model of the choice situation even when they have no initial causal hypotheses, which (d) enables them to adapt their choices to changes of the decision problem. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  18. Do sex-specific densities affect local survival of free-ranging great tits?

    NARCIS (Netherlands)

    Michler, Stephanie P. M.; Nicolaus, Marion; Ubels, Richard; van der Velde, Marco; Both, Christiaan; Tinbergen, Joost M.; Komdeur, Jan

    2011-01-01

    Competition within sexes is expected when resources are sex specific, whereas competition between sexes can occur when similar resources are exploited. Local population density and sex ratio will determine the amount of sex-specific interactions and thus the potential degree of sex-specific

  19. Safety of Repeated Yttrium-90 Radioembolization

    International Nuclear Information System (INIS)

    Lam, Marnix G. E. H.; Louie, John D.; Iagaru, Andrei H.; Goris, Michael L.; Sze, Daniel Y.

    2013-01-01

    Purpose: Repeated radioembolization (RE) treatments carry theoretically higher risk of radiation-induced hepatic injury because of the liver’s cumulative memory of previous exposure. We performed a retrospective safety analysis on patients who underwent repeated RE. Methods: From 2004 to 2011, a total of 247 patients were treated by RE. Eight patients (5 men, 3 women, age range 51–71 years) underwent repeated treatment of a targeted territory, all with resin microspheres (SIR-Spheres; Sirtex, Lane Cove, Australia). Adverse events were graded during a standardized follow-up. In addition, the correlation between the occurrence of RE-induced liver disease (REILD) and multiple variables was investigated in univariate and multivariate analyses in all 247 patients who received RE. Results: Two patients died shortly after the second treatment (at 84 and 107 days) with signs and symptoms of REILD. Both patients underwent whole liver treatment twice (cumulative doses 3.08 and 2.66 GBq). The other 6 patients demonstrated only minor toxicities after receiving cumulative doses ranging from 2.41 to 3.88 GBq. All patients experienced objective tumor responses. In the whole population, multifactorial analysis identified three risk factors associated with REILD: repeated RE (p = 0.036), baseline serum total bilirubin (p = 0.048), and baseline serum aspartate aminotransferase (p = 0.043). Repeated RE proved to be the only independent risk factor for REILD in multivariate analysis (odds ratio 9.6; p = 0.002). Additionally, the administered activity per target volume (in GBq/L) was found to be an independent risk factor for REILD, but only in whole liver treatments (p = 0.033). Conclusion: The risk of REILD appears to be elevated for repeated RE. Objective tumor responses were observed, but establishment of safety limits will require improvement in dosimetric measurement and prediction

  20. Safety of Repeated Yttrium-90 Radioembolization

    Energy Technology Data Exchange (ETDEWEB)

    Lam, Marnix G. E. H.; Louie, John D. [Stanford University School of Medicine, Division of Interventional Radiology (United States); Iagaru, Andrei H.; Goris, Michael L. [Stanford University School of Medicine, Division of Nuclear Medicine (United States); Sze, Daniel Y., E-mail: dansze@stanford.edu [Stanford University School of Medicine, Division of Interventional Radiology (United States)

    2013-10-15

    Purpose: Repeated radioembolization (RE) treatments carry theoretically higher risk of radiation-induced hepatic injury because of the liver's cumulative memory of previous exposure. We performed a retrospective safety analysis on patients who underwent repeated RE. Methods: From 2004 to 2011, a total of 247 patients were treated by RE. Eight patients (5 men, 3 women, age range 51-71 years) underwent repeated treatment of a targeted territory, all with resin microspheres (SIR-Spheres; Sirtex, Lane Cove, Australia). Adverse events were graded during a standardized follow-up. In addition, the correlation between the occurrence of RE-induced liver disease (REILD) and multiple variables was investigated in univariate and multivariate analyses in all 247 patients who received RE. Results: Two patients died shortly after the second treatment (at 84 and 107 days) with signs and symptoms of REILD. Both patients underwent whole liver treatment twice (cumulative doses 3.08 and 2.66 GBq). The other 6 patients demonstrated only minor toxicities after receiving cumulative doses ranging from 2.41 to 3.88 GBq. All patients experienced objective tumor responses. In the whole population, multifactorial analysis identified three risk factors associated with REILD: repeated RE (p = 0.036), baseline serum total bilirubin (p = 0.048), and baseline serum aspartate aminotransferase (p = 0.043). Repeated RE proved to be the only independent risk factor for REILD in multivariate analysis (odds ratio 9.6; p = 0.002). Additionally, the administered activity per target volume (in GBq/L) was found to be an independent risk factor for REILD, but only in whole liver treatments (p = 0.033). Conclusion: The risk of REILD appears to be elevated for repeated RE. Objective tumor responses were observed, but establishment of safety limits will require improvement in dosimetric measurement and prediction.

  1. ATXN2 trinucleotide repeat length correlates with risk of ALS.

    Science.gov (United States)

    Sproviero, William; Shatunov, Aleksey; Stahl, Daniel; Shoai, Maryam; van Rheenen, Wouter; Jones, Ashley R; Al-Sarraj, Safa; Andersen, Peter M; Bonini, Nancy M; Conforti, Francesca L; Van Damme, Philip; Daoud, Hussein; Del Mar Amador, Maria; Fogh, Isabella; Forzan, Monica; Gaastra, Ben; Gellera, Cinzia; Gitler, Aaron D; Hardy, John; Fratta, Pietro; La Bella, Vincenzo; Le Ber, Isabelle; Van Langenhove, Tim; Lattante, Serena; Lee, Yi-Chung; Malaspina, Andrea; Meininger, Vincent; Millecamps, Stéphanie; Orrell, Richard; Rademakers, Rosa; Robberecht, Wim; Rouleau, Guy; Ross, Owen A; Salachas, Francois; Sidle, Katie; Smith, Bradley N; Soong, Bing-Wen; Sorarù, Gianni; Stevanin, Giovanni; Kabashi, Edor; Troakes, Claire; van Broeckhoven, Christine; Veldink, Jan H; van den Berg, Leonard H; Shaw, Christopher E; Powell, John F; Al-Chalabi, Ammar

    2017-03-01

    We investigated a CAG trinucleotide repeat expansion in the ATXN2 gene in amyotrophic lateral sclerosis (ALS). Two new case-control studies, a British dataset of 1474 ALS cases and 567 controls, and a Dutch dataset of 1328 ALS cases and 691 controls were analyzed. In addition, to increase power, we systematically searched PubMed for case-control studies published after 1 August 2010 that investigated the association between ATXN2 intermediate repeats and ALS. We conducted a meta-analysis of the new and existing studies for the relative risks of ATXN2 intermediate repeat alleles of between 24 and 34 CAG trinucleotide repeats and ALS. There was an overall increased risk of ALS for those carrying intermediate sized trinucleotide repeat alleles (odds ratio 3.06 [95% confidence interval 2.37-3.94]; p = 6 × 10 -18 ), with an exponential relationship between repeat length and ALS risk for alleles of 29-32 repeats (R 2  = 0.91, p = 0.0002). No relationship was seen for repeat length and age of onset or survival. In contrast to trinucleotide repeat diseases, intermediate ATXN2 trinucleotide repeat expansion in ALS does not predict age of onset but does predict disease risk. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

  2. Differentiation of Sex Chromosomes and Karyotype Characterisation in the Dragonsnake Xenodermus javanicus (Squamata: Xenodermatidae)

    Czech Academy of Sciences Publication Activity Database

    Rovatsos, M.; Johnson Pokorná, Martina; Kratochvíl, L.

    2015-01-01

    Roč. 147, č. 1 (2015), s. 48-54 ISSN 1424-8581 Institutional support: RVO:67985904 Keywords : interstitial telomeric repeats * sex chromosomes * sex determination Subject RIV: EG - Zoology Impact factor: 1.638, year: 2015

  3. Dependence of the bone-to-soft-part ratios in skeletal scintigrams on the type of the malignans disease, morphological alterations visible by X-ray, laboratory parameters, age and sex of patients

    International Nuclear Information System (INIS)

    Pfeifer, H.

    1982-01-01

    This study was aimed to establish whether in tumor patients information detectable by scintigrams on diffuse pathological bone alterations can be obtained prior to or without typical foci of radioactivity being discoverable. By means of a quantitative evaluation of the scintigrams consisting in a comparison of the ratios of counting rate densities, the attempt was made to find out whether there were differences between visually ''normal'' scintigrams of patients with malignant tumors with a tendency towards metastatic spread into the skeletal system, and such same scans of patients without carcinomas showing no clinical signs of bone diseases. Laboratory values including serum creatinine as a parameter of renal function, as well as the administration of a tumor-specific therapy were additionally put in correlation with their possible influence on the accumulation of sup(99m)technetium-tin-phosphate compounds in bones. (orig./MG) [de

  4. Expansion of protein domain repeats.

    Directory of Open Access Journals (Sweden)

    Asa K Björklund

    2006-08-01

    Full Text Available Many proteins, especially in eukaryotes, contain tandem repeats of several domains from the same family. These repeats have a variety of binding properties and are involved in protein-protein interactions as well as binding to other ligands such as DNA and RNA. The rapid expansion of protein domain repeats is assumed to have evolved through internal tandem duplications. However, the exact mechanisms behind these tandem duplications are not well-understood. Here, we have studied the evolution, function, protein structure, gene structure, and phylogenetic distribution of domain repeats. For this purpose we have assigned Pfam-A domain families to 24 proteomes with more sensitive domain assignments in the repeat regions. These assignments confirmed previous findings that eukaryotes, and in particular vertebrates, contain a much higher fraction of proteins with repeats compared with prokaryotes. The internal sequence similarity in each protein revealed that the domain repeats are often expanded through duplications of several domains at a time, while the duplication of one domain is less common. Many of the repeats appear to have been duplicated in the middle of the repeat region. This is in strong contrast to the evolution of other proteins that mainly works through additions of single domains at either terminus. Further, we found that some domain families show distinct duplication patterns, e.g., nebulin domains have mainly been expanded with a unit of seven domains at a time, while duplications of other domain families involve varying numbers of domains. Finally, no common mechanism for the expansion of all repeats could be detected. We found that the duplication patterns show no dependence on the size of the domains. Further, repeat expansion in some families can possibly be explained by shuffling of exons. However, exon shuffling could not have created all repeats.

  5. Sex. Dev.

    OpenAIRE

    Jakubiczka, S.; Schröder, C.; Ullmann, R.; Volleth, M.; Ledig, S.; Gilberg, E.; Kroisel, P.; P. Wieacker, P.

    2010-01-01

    Campomelic dysplasia (MIM 114290) is a severe malformation syndrome frequently accompanied by male-to-female sex reversal. Causative are mutations within the SOX9 gene on 17q24.3 as well as chromosomal aberrations (translocations, inversions or deletions) in the vicinity of SOX9 . Here, we report on a patient with muscular hypotonia, craniofacial dysmorphism, cleft palate, brachydactyly, malformations of thoracic spine, and gonadal dysgenesis with female external genitalia and müllerian duct ...

  6. Film repeats in radiology department

    International Nuclear Information System (INIS)

    Suwan, A. Z.; Al-Shakharah, A. I

    1997-01-01

    During a one year period, 4910 radiographs of 55780 films were repeated. The objective of our study was to analyse and to classify the causes in order to minimize the repeats, cut the expenses and to provide optimal radiographs for accurate diagnosis. Analysis of the different factors revealed that, 43.6% of film repeats in our service were due to faults in exposure factors, centering comprises 15.9% of the repeats, while too much collimation was responsible for 7.6% of these repeats. All of which can be decreased by awareness and programmed training of technicians. Film blurring caused by patient motion was also responsible for 4.9% for radiographs reexamination, which can be minimized by detailed explanation to the patient and providing the necessary privacy. Fogging of X-Ray films by improper storage or inadequate handling or processing faults were responsible for 14.5% in repeats in our study. Methods and criteria for proper storage and handling of films were discussed. Recommendation for using modern day-light and laser processor has been high lighted. Artefacts are noticeably high in our cases, due to spinal dresses and frequent usage of precious metals for c osmotic purposes in this part of the world. The repeated films comprise 8.8% of all films We conclude that, the main factor responsible for repeats of up to 81.6% of cases was the technologists, thus emphasizing the importance of adequate training of the technologists. (authors). 15 refs., 9 figs., 1 table

  7. Nifty Nines and Repeating Decimals

    Science.gov (United States)

    Brown, Scott A.

    2016-01-01

    The traditional technique for converting repeating decimals to common fractions can be found in nearly every algebra textbook that has been published, as well as in many precalculus texts. However, students generally encounter repeating decimal numerals earlier than high school when they study rational numbers in prealgebra classes. Therefore, how…

  8. Repeated Prescribed Burning in Aspen

    Science.gov (United States)

    Donald A. Perala

    1974-01-01

    Infrequent burning weather, low flammability of the aspen-hardwood association, and prolific sprouting and seeding of shrubs and hardwoods made repeated dormant season burning a poor tool to convert good site aspen to conifers. Repeat fall burns for wildlife habitat maintenance is workable if species composition changes are not important.

  9. A COMPARISON OF PAIRS FIGURE SKATERS IN REPEATED JUMPS

    Directory of Open Access Journals (Sweden)

    William A. Sands

    2012-03-01

    Full Text Available Trends in pairs figure skating have shown that increasingly difficult jumps have become an essential aspect of high-level performance, especially in the latter part of a competitive program. We compared a repeated jump power index in a 60 s repeated jump test to determine the relationship of repeated jump test to competitive rank and to measure 2D hip, knee, and ankle angles and angular velocities at 0, 20, 40, and 60 s. Eighteen National Team Pairs Figure Skaters performed a 60 s repeated jump test on a large switch-mat with timing of flight and ground durations and digital video recording. Each 60-s period was divided into 6, 10-s intervals, with power indexes (W/kg calculated for each 10-s interval. Power index by 10-s interval repeated measures ANOVAs (RMANOVA showed that males exceeded females at all intervals, and the highest power index interval was during 10 to 20 s for both sexes. RMANOVAs of angles and angular velocities showed main effects for time only. Power index and jumping techniques among figure skaters showed rapid and steady declines over the test duration. Power index can predict approximately 50% of competitive rank variance, and sex differences in jumping technique were rare

  10. Tevatron serial data repeater system

    International Nuclear Information System (INIS)

    Ducar, R.J.

    1981-01-01

    A ten megabit per second serial data repeater system has been developed for the 6.28km Tevatron accelerator. The repeaters are positioned at each of the thirty service buildings and accommodate control and abort system communications as well as distribution of the Tevatron time and energy clocks. The repeaters are transparent to the particular protocol of the transmissions. Serial data are encoded locally as unipolar two volt signals employing the self-clocking Manchester Bi-Phase code. The repeaters modulate the local signals to low-power bursts of 50 MHz rf carrier for the 260m transmission between service buildings. The repeaters also demodulate the transmission and restructure the data for local utilization. The employment of frequency discrimination techniques yields high immunity to the characteristic noise spectrum

  11. All-photonic quantum repeaters

    Science.gov (United States)

    Azuma, Koji; Tamaki, Kiyoshi; Lo, Hoi-Kwong

    2015-01-01

    Quantum communication holds promise for unconditionally secure transmission of secret messages and faithful transfer of unknown quantum states. Photons appear to be the medium of choice for quantum communication. Owing to photon losses, robust quantum communication over long lossy channels requires quantum repeaters. It is widely believed that a necessary and highly demanding requirement for quantum repeaters is the existence of matter quantum memories. Here we show that such a requirement is, in fact, unnecessary by introducing the concept of all-photonic quantum repeaters based on flying qubits. In particular, we present a protocol based on photonic cluster-state machine guns and a loss-tolerant measurement equipped with local high-speed active feedforwards. We show that, with such all-photonic quantum repeaters, the communication efficiency scales polynomially with the channel distance. Our result paves a new route towards quantum repeaters with efficient single-photon sources rather than matter quantum memories. PMID:25873153

  12. Repeatability of visual acuity measurement.

    Science.gov (United States)

    Raasch, T W; Bailey, I L; Bullimore, M A

    1998-05-01

    This study investigates features of visual acuity chart design and acuity testing scoring methods which affect the validity and repeatability of visual acuity measurements. Visual acuity was measured using the Sloan and British Standard letter series, and Landolt rings. Identifiability of the different letters as a function of size was estimated, and expressed in the form of frequency-of-seeing curves. These functions were then used to simulate acuity measurements with a variety of chart designs and scoring criteria. Systematic relationships exist between chart design parameters and acuity score, and acuity score repeatability. In particular, an important feature of a chart, that largely determines the repeatability of visual acuity measurement, is the amount of size change attributed to each letter. The methods used to score visual acuity performance also affect repeatability. It is possible to evaluate acuity score validity and repeatability using the statistical principles discussed here.

  13. When Sex Is Painful

    Science.gov (United States)

    ... AQ FREQUENTLY ASKED QUESTIONS GYNECOLOGIC PROBLEMS FAQ020 When Sex Is Painful • How common is painful sex? • What causes pain during sex? • Where is pain during sex felt? • When should ...

  14. Sex during Pregnancy

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Sex During Pregnancy KidsHealth / For Parents / Sex During Pregnancy ... satisfying and safe sexual relationship during pregnancy. Is Sex During Pregnancy Safe? Sex is considered safe during ...

  15. Seed sexing revealed female bias in two Rumex species

    Directory of Open Access Journals (Sweden)

    Dagmara Kwolek

    2011-07-01

    Full Text Available Sex-ratio bias in seeds of dioecious Rumex species with sex chromosomes is an interesting and still unsettled issue. To resolve gender among seeds of R. acetosa and R. thyrsiflorus (two species with an XX/XY1Y2 sex chromosome system, this work applied a PCR-based method involving DNA markers located on Y chromosomes. Both species showed female-biased primary sex ratios, with female bias greater in R. acetosa than in R. thyrsiflorus. The observed predominance of female seeds is consistent with the view that the female biased sex ratios in Rumex are conditioned not only postzygotically but also prezygotically.

  16. Sex, spite, and selfish genes

    Indian Academy of Sciences (India)

    Nature's oracle: the life and work of W. D. Hamilton. Ullica Segerstrale .... Stemming partly from his study of sex ratios, Hamilton later began moving on to .... any scientific biography, has to strike a balance between sci- ence and the personal ...

  17. Fetal sex determination in the first trimester of pregnancy using a Y chromosome-specific DNA probe

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Y.; Huang, S.; Chen, M.; Huang, Y.; Zhang, M.; Dong, J.; Ku, A.; Xu, S.

    1987-05-01

    Prenatal determination of fetal sex is important for the prevention of X-linked disorders such as hemophilia, Lesch-Nyhan syndrome and Duchenne muscular dystrophy. The complex procedures of prenatal diagnosis for X-linked disorders are unnecessary if the fetus is female, because usually no clinical symptoms ever appear in female. pY 3.4 probe used in this work for sex determination is a 3.4 kilobase human repeat sequence. The probe is specific for the Y chromosome of males and can be used for sex determination. The other prove pBLUR used in this paper as control is a widely dispersed, highly repeated human Alu family DNA sequence, represented equally in male and female DNA. On the basis of the relative densities of the autoradiographic spots produced by hybridization of fetal DNA with pY3.4 and pBLUR, the sex of fetus can be clearly identified. Further the authors can determine the radioactive intensity (cpm) of the hybridized DNA spots and the ratio of hybridization with Y3.4 to pBLUR (Y3.4/pBLUR x 10). Results show that the hybridization ratio of DNA from chorionic villi of male (1.03 +/- 0.24) is significantly higher than that of female (0.16 +/- 0.09). Therefore, sex determination of the fetus can be made, based on the ratio of pY3.4/pBLUR x 10. If necessary they can also use Southern hybridization with pY 3.4 probe of DNA isolated from chorionic villi to confirm the result of dot hybridization.

  18. The sex and sex determination in Pyropia haitanensis (Bangiales, Rhodophyta).

    Science.gov (United States)

    Zhang, Yuan; Yan, Xing-hong; Aruga, Yusho

    2013-01-01

    Pyropia haitanensis has a biphasic life cycle with macroscopic gametophytic blade (n) and microscopic filamentous conchocelis (2n) phase. Its gametophytic blades have long been believed to be mainly dioecious. However, when crossing the red mutant (R, ♀) with the wild type (W, ♂), the parental colors were segregated in F1 blades, of which 96.1% were linearly sectored with 2-4 color sectors. When color sectors were excised from the color-sectored blades and cultured singly, 99.7% of the color sectors appeared to be unisexual with an equal sex ratio. Although the sex of color sector did not genetically link with its color, the boundaries of both sex and color sectors coincided precisely. About 87.9% of the examined color-sectored blades were monoecious and the percentage increased with the number of color sectors of a blade. The gametophytic blades from each conchocelis strain produced by parthenogenesis of the excised color sectors were unisexual and unicolor, showing the same sex and color as their original sectors. These results indicate that most of the sexually reproduced Py. haitanensis blades are monoecious, and their sex is controlled by segregation of a pair of alleles during meiosis of conchospore, forming a sex-sectored tetrad. During the subsequent development of blades, one or two lower cell(s) of the tetrad contribute mainly to rhizoid formation, and rarely show their sexual phenotype, leading to reduced frequency of full sex phenotype of the meiotic blades. Moreover, the aberrant segregations of sex genes or color genes in a few of F1 blades were probably due to gene conversions, but there was no sex transfer in Py. haitanensis.

  19. Sex Education

    Directory of Open Access Journals (Sweden)

    R N Srivastava

    1994-06-01

    Full Text Available Sex, though not everything in life, is a profoundly important aspect of human existence. It has evolved to serve more than reproductive functions; relational and recreational functions having taken precedence over procrea­tional. Sex has come to play a much wider socio-psychological function. Human sexuality is complex and multidimensional. It is subject to influence by multitude of factors often grouped as biological (e.g. genes, hormones, psychological (e.g. fear, anxiety, mood and socio-cultural (e.g. sex roles, values- religious/moral/ethical, customs. It is the interaction and interrelationship of these factors from the time of conception, through intrauterine life, infancy, childhood and adolescence, till adulthood (even later in life that determine the sexual development expressed as sexual attitudes and behaviour of the people. Learning, both social and cognitive, plays a significantly important role in such development. Sexual dysfunctions in men and women, result from factors often categorised as physical or organic and psychological; more often a combination may be involved. Experience has shown that in majority of men and women in India having sexual problems, ignorance misconceptions and prevailing myths are invariably responsible in the causation of Ihese problems. Sexual problems in individual man (e.g. erectile failure and woman (e.g. vaginismus cause anxiety, feelings of frustration, lowered self esteem and symptoms of depression. The condition may also affect the spouse; he/she, as a reaction to the problem in the partner, may develop sexual and psychosocial problems including distressed marital relationship. This may also have influence on general couple relationship, effecting adversely the quality of family life. Modern therapeutic endevours have made it possible now to offer effective therapy to most people who seek help for their sexual problems, thus preventing the consequences on couple relationship. However, there is

  20. SEX EDUCATION

    Directory of Open Access Journals (Sweden)

    R N Srivastava

    1994-06-01

    Full Text Available Sex, though not everything in life, is a profoundly important aspect of human existence. It has evolved to serve more than reproductive functions; relational and recreational functions having taken precedence over procrea­tional. Sex has come to play a much wider socio-psychological function.Human sexuality is complex and multidimensional. It is subject to influence by multitude of factors often grouped as biological (e.g. genes, hormones, psychological (e.g. fear, anxiety, mood and socio-cultural (e.g. sex roles, values- religious/moral/ethical, customs. It is the interaction and interrelationship of these factors from the time of conception, through intrauterine life, infancy, childhood and adolescence, till adulthood (even later in life that determine the sexual development expressed as sexual attitudes and behaviour of the people. Learning, both social and cognitive, plays a significantly important role in such development.Sexual dysfunctions in men and women, result from factors often categorised as physical or organic and psychological; more often a combination may be involved. Experience has shown that in majority of men and women in India having sexual problems, ignorance misconceptions and prevailing myths are invariably responsible in the causation of Ihese problems. Sexual problems in individual man (e.g. erectile failure and woman (e.g. vaginismus cause anxiety, feelings of frustration, lowered self esteem and symptoms of depression. The condition may also affect the spouse; he/she, as a reaction to the problem in the partner, may develop sexual and psychosocial problems including distressed marital relationship. This may also have influence on general couple relationship, effecting adversely the quality of family life.Modern therapeutic endevours have made it possible now to offer effective therapy to most people who seek help for their sexual problems, thus preventing the consequences on couple relationship. However, there is also

  1. Unusually dynamic sex roles in a fish.

    Science.gov (United States)

    Forsgren, Elisabet; Amundsen, Trond; Borg, Asa A; Bjelvenmark, Jens

    2004-06-03

    Sex roles are typically thought of as being fixed for a given species. In most animals males compete for females, whereas the females are more reluctant to mate. Therefore sexual selection usually acts most strongly on males. This is explained by males having a higher potential reproductive rate than females, leading to more males being sexually active (a male-biased operational sex ratio). However, what determines sex roles and the strength of sexual selection is a controversial and much debated question. In this large-scale field study, we show a striking temporal plasticity in the mating competition of a fish (two-spotted goby, Gobiusculus flavescens). Over the short breeding season fierce male-male competition and intensive courtship behaviour in males were replaced by female-female competition and actively courting females. Hence, sex role reversal occurred rapidly. This is the first time that a shift in sex roles has been shown in a vertebrate. The shift might be explained by a large decline in male abundance, strongly skewing the sex ratio towards females. Notably, the sex role reversal did not occur at an equal operational sex ratio, contrary to established sex role theory.

  2. Analysis of repeated measures data

    CERN Document Server

    Islam, M Ataharul

    2017-01-01

    This book presents a broad range of statistical techniques to address emerging needs in the field of repeated measures. It also provides a comprehensive overview of extensions of generalized linear models for the bivariate exponential family of distributions, which represent a new development in analysing repeated measures data. The demand for statistical models for correlated outcomes has grown rapidly recently, mainly due to presence of two types of underlying associations: associations between outcomes, and associations between explanatory variables and outcomes. The book systematically addresses key problems arising in the modelling of repeated measures data, bearing in mind those factors that play a major role in estimating the underlying relationships between covariates and outcome variables for correlated outcome data. In addition, it presents new approaches to addressing current challenges in the field of repeated measures and models based on conditional and joint probabilities. Markov models of first...

  3. Repeated DNA sequences in fungi

    Energy Technology Data Exchange (ETDEWEB)

    Dutta, S K

    1974-11-01

    Several fungal species, representatives of all broad groups like basidiomycetes, ascomycetes and phycomycetes, were examined for the nature of repeated DNA sequences by DNA:DNA reassociation studies using hydroxyapatite chromatography. All of the fungal species tested contained 10 to 20 percent repeated DNA sequences. There are approximately 100 to 110 copies of repeated DNA sequences of approximately 4 x 10/sup 7/ daltons piece size of each. Repeated DNA sequence homoduplexes showed on average 5/sup 0/C difference of T/sub e/50 (temperature at which 50 percent duplexes dissociate) values from the corresponding homoduplexes of unfractionated whole DNA. It is suggested that a part of repetitive sequences in fungi constitutes mitochondrial DNA and a part of it constitutes nuclear DNA. (auth)

  4. Fostering repeat donations in Ghana.

    Science.gov (United States)

    Owusu-Ofori, S; Asenso-Mensah, K; Boateng, P; Sarkodie, F; Allain, J-P

    2010-01-01

    Most African countries are challenged in recruiting and retaining voluntary blood donors by cost and other complexities and in establishing and implementing national blood policies. The availability of replacement donors who are a cheaper source of blood has not enhanced repeat voluntary donor initiatives. An overview of activities for recruiting and retaining voluntary blood donors was carried out. Donor records from mobile sessions were reviewed from 2002 to 2008. A total of 71,701 blood donations; 45,515 (63.5%) being voluntary donations with 11,680 (25%) repeat donations were collected during the study period. Donations from schools and colleges contributed a steady 60% of total voluntary whilst radio station blood drives increased contribution from 10 to 27%. Though Muslim population is less than 20%, blood collection was above the 30-donation cost-effectiveness threshold with a repeat donation trend reaching 60%. In contrast Christian worshippers provided donations. Repeat donation trends amongst school donors and radio blood drives were 20% and 70% respectively. Repeat donations rates have been variable amongst different blood donor groups in Kumasi, Ghana. The impact of community leaders in propagating altruism cannot be overemphasized. Programs aiming at motivating replacement donors to be repeat donors should be developed and assessed. Copyright 2009 The International Association for Biologicals. All rights reserved.

  5. Quantitative sexing (Q-Sexing) and relative quantitative sexing (RQ ...

    African Journals Online (AJOL)

    samer

    Key words: Polymerase chain reaction (PCR), quantitative real time polymerase chain reaction (qPCR), quantitative sexing, Siberian tiger. INTRODUCTION. Animal molecular sexing .... 43:3-12. Ellegren H (1996). First gene on the avian W chromosome (CHD) provides a tag for universal sexing of non-ratite birds. Proc.

  6. Repeated transsphenoidal surgery or gamma knife radiosurgery in recurrent cushing disease after transsphenoidal surgery.

    Science.gov (United States)

    Bodaghabadi, Mohammad; Riazi, Hooman; Aran, Shima; Bitaraf, Mohammad Ali; Alikhani, Mazdak; Alahverdi, Mahmud; Mohamadi, Masoumeh; Shalileh, Keivan; Azar, Maziar

    2014-03-01

    This study compared Gamma knife radiosurgery (GKRS) and repeated transsphenoidal adenomectomy (TSA) to find the best approach for recurrence of Cushing disease (CD) after unsuccessful first TSA. Fifty-two patients with relapse of CD after TSA were enrolled and randomly underwent a second surgery or GKRS as the next therapeutic approach. They were followed for a mean period of 3.05 ± 0.8 years by physical examination and hormone measurement as well as magnetic resonance imaging. No significant difference was observed in sex ratio, mean age, adenoma type, follow-up duration, and initial hormone level between the two groups. No significant relationship was found between preoperative 24-hour free urine cortisol and disease-free months or tumor volume among both groups. Our statistical analysis showed higher recurrence-free interval in the GKRS group compared with TSA group. With longer recurrence-free interval, GKRS could be considered a good treatment alternative to repeated TSA in recurrent CD. Georg Thieme Verlag KG Stuttgart · New York.

  7. Climate change is associated with male:female ratios of fetal deaths and newborn infants in Japan

    DEFF Research Database (Denmark)

    Fukuda, Misao; Fukuda, Kiyomi; Shimizu, Takashi

    2014-01-01

    . INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Yearly sex ratios of fetal deaths and newborn infants and monthly fetal death rates and sex ratios of newborn infants. RESULT(S): A statistically significant positive association was found between yearly temperature differences and sex ratios of fetal deaths......; a statistically significant negative association was found between temperature differences and sex ratios of newborn infants from 1968 to 2012, and between sex ratios of births and of fetal deaths. The sex ratios of fetal deaths have been increasing steadily along with temperature differences, whereas the sex......OBJECTIVE: To evaluate whether climate change is associated with male:female ratios (sex ratios) of fetal deaths and births in Japan. DESIGN: A population-based cohort study. SETTING: Not applicable. PATIENT(S): Newborn infants and fetuses spontaneously aborted after 12 weeks of gestation...

  8. Size distributions and sex ratios of sharks caught by Oman's ...

    African Journals Online (AJOL)

    Oman's fishery resources are exploited by artisanal and industrial fisheries, but the former accounts for almost 90% of landings. Within the artisanal fishery, sharks have traditionally been harvested for their flesh, but the development of a valuable export market for shark fin has led to increased utilisation of this resource, and ...

  9. Analysis of brood sex ratios: implications of offspring clustering

    Czech Academy of Sciences Publication Activity Database

    Krackow, S.; Tkadlec, Emil

    Roc. 50, č. 4 (2001), s. 293-301 ISSN 0340-5443 R&D Projects: GA ČR GA524/01/1316 Institutional research plan: CEZ:AV0Z6093917 Keywords : generalized linear mixed models * random coefficients * multilevel analysis Subject RIV: EG - Zoology Impact factor: 2.353, year: 2001

  10. Sexual orientation, handedness, sex ratio and fetomaternal tolerance-rejection

    OpenAIRE

    Carlos Y Valenzuela

    2010-01-01

    Fraternal birth order (FBO) appears as a prenatal cause of 15% of homosexual males (gays) through mnemonic maternal anti-male factors. Non-right-handed men seem to be protected from homosexuality. Four hypotheses are proposed: (1) androgenic factors of non-right-handedness neutralize anti-male factors; (2) non-right-handedness and homosexuality are lethal or produce mental impairment; (3) non-right-handed male embryos are insensitive to anti-male factors; (4) mothers of non-right-handed fetus...

  11. Hysteresis of magnetostructural transitions: Repeatable and non-repeatable processes

    Science.gov (United States)

    Provenzano, Virgil; Della Torre, Edward; Bennett, Lawrence H.; ElBidweihy, Hatem

    2014-02-01

    The Gd5Ge2Si2 alloy and the off-stoichiometric Ni50Mn35In15 Heusler alloy belong to a special class of metallic materials that exhibit first-order magnetostructural transitions near room temperature. The magnetic properties of this class of materials have been extensively studied due to their interesting magnetic behavior and their potential for a number of technological applications such as refrigerants for near-room-temperature magnetic refrigeration. The thermally driven first-order transitions in these materials can be field-induced in the reverse order by applying a strong enough field. The field-induced transitions are typically accompanied by the presence of large magnetic hysteresis, the characteristics of which are a complicated function of temperature, field, and magneto-thermal history. In this study we show that the virgin curve, the major loop, and sequentially measured MH loops are the results of both repeatable and non-repeatable processes, in which the starting magnetostructural state, prior to the cycling of field, plays a major role. Using the Gd5Ge2Si2 and Ni50Mn35In15 alloys, as model materials, we show that a starting single phase state results in fully repeatable processes and large magnetic hysteresis, whereas a mixed phase starting state results in non-repeatable processes and smaller hysteresis.

  12. Hysteresis of magnetostructural transitions: Repeatable and non-repeatable processes

    International Nuclear Information System (INIS)

    Provenzano, Virgil; Della Torre, Edward; Bennett, Lawrence H.; ElBidweihy, Hatem

    2014-01-01

    The Gd 5 Ge 2 Si 2 alloy and the off-stoichiometric Ni 50 Mn 35 In 15 Heusler alloy belong to a special class of metallic materials that exhibit first-order magnetostructural transitions near room temperature. The magnetic properties of this class of materials have been extensively studied due to their interesting magnetic behavior and their potential for a number of technological applications such as refrigerants for near-room-temperature magnetic refrigeration. The thermally driven first-order transitions in these materials can be field-induced in the reverse order by applying a strong enough field. The field-induced transitions are typically accompanied by the presence of large magnetic hysteresis, the characteristics of which are a complicated function of temperature, field, and magneto-thermal history. In this study we show that the virgin curve, the major loop, and sequentially measured MH loops are the results of both repeatable and non-repeatable processes, in which the starting magnetostructural state, prior to the cycling of field, plays a major role. Using the Gd 5 Ge 2 Si 2 and Ni 50 Mn 35 In 15 alloys, as model materials, we show that a starting single phase state results in fully repeatable processes and large magnetic hysteresis, whereas a mixed phase starting state results in non-repeatable processes and smaller hysteresis

  13. Sex-linked dominant

    Science.gov (United States)

    Inheritance - sex-linked dominant; Genetics - sex-linked dominant; X-linked dominant; Y-linked dominant ... can be either an autosomal chromosome or a sex chromosome. It also depends on whether the trait ...

  14. Multiple sex partner

    African Journals Online (AJOL)

    User

    intercourse, about 60% reported having a single sexual partner and 40% reported having multiple ... masturbation, start having sex at a younger age, have sex with married people and/or .... sex were considered unacceptable by 89 vs.

  15. Repeatability and consistency of individual behaviour in juvenile and adult Eurasian harvest mice

    Science.gov (United States)

    Schuster, Andrea C.; Carl, Teresa; Foerster, Katharina

    2017-04-01

    Knowledge on animal personality has provided new insights into evolutionary biology and animal ecology, as behavioural types have been shown to affect fitness. Animal personality is characterized by repeatable and consistent between-individual behavioural differences throughout time and across different situations. Behavioural repeatability within life history stages and consistency between life history stages should be checked for the independence of sex and age, as recent data have shown that males and females in some species may differ in the repeatability of behavioural traits, as well as in their consistency. We measured the repeatability and consistency of three behavioural and one cognitive traits in juvenile and adult Eurasian harvest mice ( Micromys minutus). We found that exploration, activity and boldness were repeatable in juveniles and adults. Spatial recognition measured in a Y Maze was only repeatable in adult mice. Exploration, activity and boldness were consistent before and after maturation, as well as before and after first sexual contact. Data on spatial recognition provided little evidence for consistency. Further, we found some evidence for a litter effect on behaviours by comparing different linear mixed models. We concluded that harvest mice express animal personality traits as behaviours were repeatable across sexes and consistent across life history stages. The tested cognitive trait showed low repeatability and was less consistent across life history stages. Given the rising interest in individual variation in cognitive performance, and in its relationship to animal personality, we suggest that it is important to gather more data on the repeatability and consistency of cognitive traits.

  16. Sex allocation in the sexually monomorphic fairy martin

    NARCIS (Netherlands)

    Magrath, MJL; Green, DJ; Komdeur, J

    Offspring sex ratios were examined at the population and family level in the sexually monomorphic, socially monogamous fairy martin Petrochelidon ariel at five colony sites over a 4-year period (1993 1996). The sex of 465 nestlings from 169 broods % as determined using sex-specific PCR at the CHD

  17. Dynamics of urban population growth in Nigeria: The role of repeated migration.

    Science.gov (United States)

    Adepoju, A

    1976-02-01

    The paper examines the direct contribution of migration to the growth of the urban population both in terms of its mobility and stability components with special reference to Western Nigeria. The basis of the paper is a survey of urban migration conducted by the author in 1971-1972; the findings are supplemented where necessary by the 1952-1953 and 1963 census figures. Migration is a major factor in the growth of the urban population. The direct contribution by migrants to such growth can be traced to the following groups: the initial streams of migrants, the follow-up migrants and the potentially mobile migrants attracted from the migrants' communities of origin to the towns. Repeated migration by some migrants, particularly the young, the educated and the white collar-workers, are also major factors in the urban population growth. Such repeated migrations are predominantly urban to urban or turnover moves. The high mobility rate among a group of migrants tends to conceal the relative stability among the migrant population as a whole. Repeated migrants usually stay between 3 and 5 years at each destination, before moving on. A substantial proportion of migrants, mainly farmers, the less educated and the old, are relatively stable in the survey towns (Ife and Oshogho). The urban residence ration indices also indicate an increase in the rate of immigration, mainly of young persons, to the towns. The youthful age structure, the age selectivity in migration and the marital status of the young migrants tend to exacerbate the masculinity in the form of unbalanced sex ratio prevailing in most urban centers. The urban population is unlikely to be stable. The tendency for old migrants of rural origin to return to their villages at the end of their migration career and for contemporary migrants to consist predominantly of youths, will for the next generation or 2 lead to a young and unstable urban population.

  18. Sex differentials in mortality.

    Science.gov (United States)

    1970-06-01

    The questions leing considered are whether a higher female than male mortality rate exists in Ceylon, India, and Pakistan, and whether this sex differential can account for the observed high male sex ratios. There is a choice between explaining the recorded masculinity of the Indian population by assuming that the subordinate position of women caused their omission from the census or that it caused their unrecorded death in childhood. The 1951 census report of India states that there is a traditional fondness for male issues in most parts of the country and a corresponding dislike for female children. However, a life table for India applied to the 1951 census gave a higher average female age at death 34.7 years as opposed to 33.5 years for male. Other estimates for India and Pakistan for the period 1951-1961 give 37.8 years for life expectancy for males and 36.98 for females. In 1953 the female death rate in Ceylon was over 80% higher than that of the males in the most reproductive ages, 20-29. In 1963 the female excess mortality at the same ages was still 25%, and in the age group 30-34 almost a 1/3 higher. In India the female death rate at ages 15-44 was 38% higher than that of the males in the 1958-1959 survey and as much as 174% higher in the Khanna rural survey, 1956-1960. In Pakistan a Population growth Estimate experiment conducted during 1962-1965 on a national probability sample has shown that in the ages 15-44 the female death rate was 75% higher than that of the males. High maternal mortality was the major reason. In addition, female mortality among young children over age 1 year was 24% higher in 1965 and 1963. There was little difference between the rates of mortality of the 2 sexes at age 45 and above. Recent trends in Ceylon show considerable improvement in maternal mortality which has reduced by 22% the ratio of female to male mortality at age 15-44. Also the ratio at ages 1-9 fell by 8%. to .1 of a year for every calendar year to 1980.

  19. No evidence for sex-specific effects of the maternal social environment on offspring development in Japanese quail (Coturnix japonica).

    Science.gov (United States)

    Langen, Esther M A; von Engelhardt, Nikolaus; Goerlich-Jansson, Vivian C

    2018-07-01

    The social environment of reproducing females can cause physiological changes, with consequences for reproductive investment and offspring development. These prenatal maternal effects are often found to be sex-specific and may have evolved as adaptations, maximizing fitness of male and female offspring for their future environment. Female hormone levels during reproduction are considered a potential mechanism regulating sex allocation in vertebrates: high maternal androgens have repeatedly been linked to increased investment in sons, whereas high glucocorticoid levels are usually related to increased investment in daughters. However, results are not consistent across studies and therefore still inconclusive. In Japanese quail (Coturnix japonica), we previously found that pair-housed females had higher plasma androgen levels and tended to have higher plasma corticosterone levels than group-housed females. In the current study we investigate whether these differences in maternal social environment and physiology affect offspring sex allocation and physiology. Counter to our expectations, we find no effects of the maternal social environment on offspring sex ratio, sex-specific mortality, growth, circulating androgen or corticosterone levels. Also, maternal corticosterone or androgen levels do not correlate with offspring sex ratio or mortality. The social environment during reproduction therefore does not necessarily modify sex allocation and offspring physiology, even if it causes differences in maternal physiology. We propose that maternal effects of the social environment strongly depend upon the type of social stimuli and the timing of changes in the social environment and hormones with respect to the reproductive cycle and meiosis. Copyright © 2018 Elsevier Inc. All rights reserved.

  20. Coordination in continuously repeated games

    NARCIS (Netherlands)

    Weeren, A.J.T.M.; Schumacher, J.M.; Engwerda, J.C.

    1995-01-01

    In this paper we propose a model to describe the effectiveness of coordination in a continuously repeated two-player game. We study how the choice of a decision rule by a coordinator affects the strategic behavior of the players, resulting in more or less cooperation. Our model requires the analysis

  1. Repeated checking causes memory distrust

    NARCIS (Netherlands)

    van den Hout, M.; Kindt, M.

    2003-01-01

    This paper attempts to explain why in obsessive-compulsive disorder (OCD) checkers distrust in memory persists despite extensive checking. It is argued that: (1) repeated checking increases familiarity with the issues checked; (2) increased familiarity promotes conceptual processing which inhibits

  2. Why is digit ratio correlated to sports performance?

    Science.gov (United States)

    Kim, Tae Beom; Kim, Khae Hawn

    2016-12-01

    Second to fourth digit ratio is the ratio of second to fourth digit length. It has been known that digit ratio is sexually dimorphic in humans, such that males tend to have lower digit ratio (longer fourth digits relative to second digits) than females. Digit ratio is thought to be a biomarker of the balance between fetal testosterone (FT) and fetal estrogen (FE) in a relatively narrow developmental window at the end of the first trimester of pregnancy. On the contrary, the relationships between digit ratio and levels of sex steroids in adults are not clear. Most correlational studies between digit ratio and adult sex steroids have revealed that this association is statistically not significant. However, for many years, a lot of researches showed negative relationships between digit ratio and sports performance such as rugby, surfing, rowing, sprinting, endurance, and hand grip strength. Here, we discuss possible mechanisms about the relationships between digit ratio and sports performance.

  3. Understanding Sex for Sale

    DEFF Research Database (Denmark)

    This book Understanding Sex for Sale: Meanings and Moralities of Sexual Commerce is dedicated to the exploration of the ways in which sex prostitution, sex work or sex for sale are taken for granted by particularly looking at how the relation between sex and money is interpreted and enacted....... This interdisciplinary book aims to understand how prostitution, sex work or sex for sale are defined, delineated, contested and understood in different places and times. The book offers contributions from a number of scholars who, based on their on their own research, discuss on going theoretical issues and analytical...... challenges Some chapters focuses on how prostitution, sex work or sex for sale have been regulated by the authorities and what understandings this regulation builds on. Other chapters investigate the experiences of the sex workers and sex buyers asking how these actors adjust to or resist the categorisation...

  4. Repeat Chlamydia trachomatis testing among heterosexual STI outpatient clinic visitors in the Netherlands: a longitudinal study.

    Science.gov (United States)

    Visser, Maartje; van Aar, Fleur; Koedijk, Femke D H; Kampman, Carolina J G; Heijne, Janneke C M

    2017-12-20

    Chlamydia infections are common in both men and women, are often asymptomatic and can cause serious complications. Repeat testing in high-risk groups is therefore indicated. In the Netherlands, guidelines on repeat chlamydia testing differ between testing facilities, and knowledge on repeat testing behaviour is limited. Here, we analyse the current repeat testing behaviour of heterosexual STI clinic visitors, and aim to identify groups for which repeat testing advice could be advantageous. Longitudinal surveillance data from all Dutch STI outpatient clinics were used, which included all STI clinic consultations carried out among heterosexual men and women between June 2014 and December 2015. Repeat testing was defined as returning to the same STI clinic between 35 days and 12 months after initial consultation. We calculated chlamydia positivity at repeat test stratified by initial test result and time between consultations. Logistic regression analyses were used to identify predictors of repeat testing, and predictors of having a chlamydia positive repeat test. In total, 140,486 consultations in 75,487 women and 46,286 men were available for analyses. Overall, 15.4% of women and 11.1% of men returned to the STI clinic within the study period. Highest chlamydia positivity at repeat test was seen 3-5 months after initial positive test. Among both women and men, repeat testing was associated with non-Western ethnicity, having had more than two sex partners in the past 6 months, reporting STI symptoms, having a history of STI, and having a chlamydia positive initial test. Among repeat testers, chlamydia positive repeat test was most strongly associated with younger age, followed by a chlamydia positive initial test. Repeat testing most often resulted in a positive test result among young heterosexuals (<25) and heterosexuals of any age with a chlamydia infection at the initial consultation. Further efforts are needed to determine optimal repeat testing strategies.

  5. Sex preferences among mothers delivering at Patan Hospital.

    Science.gov (United States)

    Chhetri, U D; Ansari, I; Bandary, S; Adhikari, N

    2011-01-01

    High sex ratios at birth (SRB) are seen in China, Taiwan, South Korea, parts of India and Vietnam. The imbalance is the result of son preference, accentuated by declining fertility. Prenatal sex determination and female feticides are common in many countries. It is reflected in sex ratio To determine reasons for the preferences for different sex; to find out whether there is altered sex ratio at birth and to find out whether female feticide are common among women who had abortion. It is a prospective study. Women who had previous history of abortion and had delivered at Patan Hospital in the year 2066 were interviewed as per questionnaires. Among 560 women with total live births of 965, (462 male and 503 female) during their life time the overall sex ratio was 92 male per 100 female birth; total abortions were 663. Preferences for male were 10%, female 15.4% and either was for 74%. The reason for male preference was to continue family lineage, to bring honor, old age security, and performing funeral rites while the reasons for daughter preferences were that they understand mothers pain, help in household work. The sex ratio of the babies born during the study period was 113 male per 100 female births. The Sex ratio at birth from 1st to 6th deliveries was 61, 79, 101, 210, 286 and 1100 male per 100 female birth respectively. Prenatal sex selection was 8% (by USG) but none had sex selected abortion. Sex ratio of those delivered during the study period was skewed (136 boys per 100 girls) towards male. There was shift in SRB in 4th and subsequent pregnancies in favor of boys. As the male sex ratio increased the number of induced abortion decreased in subsequent pregnancies.

  6. Inheritance of nesting behaviour across natural environmental variation in a turtle with temperature-dependent sex determination.

    Science.gov (United States)

    McGaugh, Suzanne E; Schwanz, Lisa E; Bowden, Rachel M; Gonzalez, Julie E; Janzen, Fredric J

    2010-04-22

    Nesting behaviour is critical for reproductive success in oviparous organisms with no parental care. In organisms where sex is determined by incubation temperature, nesting behaviour may be a prime target of selection in response to unbalanced sex ratios. To produce an evolutionary change in response to sex-ratio selection, components of nesting behaviour must be heritable. We estimated the field heritability of two key components of nesting behaviour in a population of painted turtles (Chrysemys picta) with temperature-dependent sex determination by applying the 'animal model' to a pedigree reconstructed from genotype data. We obtained estimates of low to non-detectable heritability using repeated records across all environments. We then determined environment-specific heritability by grouping records with similar temperatures for the winter preceding the nesting season, a variable known to be highly associated with our two traits of interest, nest vegetation cover and Julian date of nesting. The heritability estimates of nest vegetation cover and Julian date of nesting were qualitatively highest and significant, or nearly so, after hot winters. Additive genetic variance for these traits was not detectable after cold winters. Our analysis suggests that the potential for evolutionary change of nesting behaviour may be dependent on the thermal conditions of the preceding winter, a season that is predicted to be especially subject to climate change.

  7. Florivory and sex ratio in Annona dioica St. Hil. (Annonaceae in the Pantanal at Nhecolândia, southwestern Brazil Florivoria e razão sexual em Annona dioica St. Hil. (Annonaceae no Pantanal da Nhecolândia, Brazil

    Directory of Open Access Journals (Sweden)

    Hipólito Ferreira Paulino Neto

    2006-06-01

    Full Text Available Annona dioica St. Hil. is a species that grows to approximately 2 m tall and is very widespread in the cerrados. Individual plants of this androdioecious species produce numerous hermaphroditic or male flowers, but few fruits. The aim of this study was to determine the sex ratio among the plants and to compare the frequency of herbivory between male and hermaphroditic flowers. The fieldwork was done by studying flowering plants in grasslands used as pasture for cattle at Fazenda Nhumirim. One hundred and forty-seven male plants and 71 hermaphroditic plants were examined and produced a total of 194 and 94 flowers, respectively, during the study period. The male:hermaphrodite sex ratio was 2.07:1, and was similar to the male:hermaphrodite flower ratio of 2.06:1. The frequency of florivory rate in hermaphrodites was significantly higher than in male flowers (33.0%, n = 31, and 25.7%, n = 50, respectively; G = 14.83; d.f. = 1; p Annona dioica é uma espécie arbustiva de até dois metros de altura, amplamente distribuída nos cerrados. Esta espécie é conhecida por oferecer muitas flores, mas produzir poucos frutos. Enquadra-se como androdióica, possuindo indivíduos machos e hermafroditas na população. O objetivo deste estudo foi registrar a razão sexual e comparar a taxa de florivoria entre flores masculinas e hermafroditas. A coleta de dados ocorreu em campos de pastagem da Fazenda Nhumirim, consistindo na observação de arbustos floridos. Foram registrados 147 indivíduos masculinos e 71 hermafroditas, os quais apresentavam um total de 194 e 94 flores durante o período de estudo, respectivamente. A razão sexual observada foi de 2,07 indivíduos masculinos para cada hermafrodita, bem como 2,06 flores masculinas para cada flor hermafrodita. A taxa de florivoria foi significativamente maior em flores hermafroditas que em masculinas, com 33,0% (n = 31 e 25,7% (n = 50, respectivamente (G = 14,83; 1gl; p < 0,001. A média do peso fresco de 50

  8. Rates of advertised condomless sex in the online profiles of private sex workers: a cross-sectional study.

    Science.gov (United States)

    Blackledge, Edjoni; Thng, Caroline; McIver, Ruthy; McNulty, Anna

    2018-02-01

    This study aimed to assess the level of condomless sex advertised online by private sex workers (PSW) in Sydney. In 2015, 750 online profiles of PSW, including 339 female, 53 male and 39 transgender PSWs, were reviewed. It was found that PSWs advertise protected anal and vaginal sex. However, 50% of female PSW advertised condomless oral sex. Age less than 25 years was associated with advertised condomless oral sex (odds ratio 1.56; 95% confidence interval 1.03-2.37; P=0.037). Online platforms are widely used for advertising, especially by female PSWs. Levels of condom use advertised reflect that of other studies of sex workers in Sydney.

  9. Financial Key Ratios

    OpenAIRE

    Tănase Alin-Eliodor

    2014-01-01

    This article focuses on computing techniques starting from trial balance data regarding financial key ratios. There are presented activity, liquidity, solvency and profitability financial key ratios. It is presented a computing methodology in three steps based on a trial balance.

  10. Online learning in repeated auctions

    OpenAIRE

    Weed, Jonathan; Perchet, Vianney; Rigollet, Philippe

    2015-01-01

    Motivated by online advertising auctions, we consider repeated Vickrey auctions where goods of unknown value are sold sequentially and bidders only learn (potentially noisy) information about a good's value once it is purchased. We adopt an online learning approach with bandit feedback to model this problem and derive bidding strategies for two models: stochastic and adversarial. In the stochastic model, the observed values of the goods are random variables centered around the true value of t...

  11. A repeating fast radio burst.

    Science.gov (United States)

    Spitler, L G; Scholz, P; Hessels, J W T; Bogdanov, S; Brazier, A; Camilo, F; Chatterjee, S; Cordes, J M; Crawford, F; Deneva, J; Ferdman, R D; Freire, P C C; Kaspi, V M; Lazarus, P; Lynch, R; Madsen, E C; McLaughlin, M A; Patel, C; Ransom, S M; Seymour, A; Stairs, I H; Stappers, B W; van Leeuwen, J; Zhu, W W

    2016-03-10

    Fast radio bursts are millisecond-duration astronomical radio pulses of unknown physical origin that appear to come from extragalactic distances. Previous follow-up observations have failed to find additional bursts at the same dispersion measure (that is, the integrated column density of free electrons between source and telescope) and sky position as the original detections. The apparent non-repeating nature of these bursts has led to the suggestion that they originate in cataclysmic events. Here we report observations of ten additional bursts from the direction of the fast radio burst FRB 121102. These bursts have dispersion measures and sky positions consistent with the original burst. This unambiguously identifies FRB 121102 as repeating and demonstrates that its source survives the energetic events that cause the bursts. Additionally, the bursts from FRB 121102 show a wide range of spectral shapes that appear to be predominantly intrinsic to the source and which vary on timescales of minutes or less. Although there may be multiple physical origins for the population of fast radio bursts, these repeat bursts with high dispersion measure and variable spectra specifically seen from the direction of FRB 121102 support an origin in a young, highly magnetized, extragalactic neutron star.

  12. Risk of sex-specific cancers in opposite-sex and same-sex twins in Denmark and Sweden

    DEFF Research Database (Denmark)

    Ahrenfeldt, Linda Juel; Skytthe, Axel; Möller, Sören

    2015-01-01

    -scale prospective twin study compared opposite-sex (OS) and same-sex (SS) twins to test the impact of intrauterine exposures on cancer risk. Based on the Danish and Swedish twin and cancer registries, we calculated incidence rate ratios for OS and SS twins while standardized incidence ratios (SIRs) with 95......% confidence intervals (CIs) were calculated for OS/SS twins compared with the general population. RESULTS: A total of 18,001 cancers were identified during 1943-2009. No significant differences were observed between OS and SS twins, neither for the sex-specific cancers nor for cancer at all sites. All...... to prenatal testosterone - does not increase the risk of sex-specific cancers in OS females. Furthermore, the study supports that twinning per se is not a risk factor of cancer. IMPACT: Findings are reassuring as they fail to provide evidence for the hypothesis that endocrine or other difference...

  13. EFFECT OF TIMING OF ARTIFICIAL INSEMINATION ON THE FERTILITY AND SEX RATIO IN NELORE HEIFERS INFLUÊNCIA DO MOMENTO DA INSEMINAÇÃO ARTIFICIAL SOBRE A FERTILIDADE E O SEXO DA CRIA DE NOVILHAS DA RAÇA NELORE

    Directory of Open Access Journals (Sweden)

    José Ricardo Almeida de Andrade

    2008-12-01

    Full Text Available The aim of this study was to evaluate the effect of timing of artificial insemination on the fertility and calf sex ratio in Nelore heifers (n = 200 submitted a protocol of timed artificial insemination (TAI.  The heifers, distributed into five groups (GC, GT6, GT12, GT18 and GT24, presented a mean of 2.5 years old and 342 Kg of body weight. The inseminations were performed in the moments 0 (GC, 6 (GT6, 12 (GT12, 18 (GT18 and 24 (GT24 hours after the injection of GnRH. The conception rates were 87.5% (GC, 82.5% (GT6, 77.5% (GT12, 85.0% (GT18 and 77.5% (GT24. There was no statistical difference (p>0.05 in the conception rates between the five treatments. The percentage of calved males was 38.2% (GC, 48.5% (GT6, 45.2% (GT12, 55.9% (GT18 and 58.6% (GT24. The male/female ratio was 0.62 (GC, 0.94 (GT6, 0.82 (GT12, 1.27 (GT18 and 1.42 (GT24. Statistical difference was found (p<0.05 in the male/female ratio between the five treatments. The timing of artificial insemination has influence on the sex ratio, showing an increase in the proportion of calved males when the insemination is progressively delayed. Within of the measured interval of time (0-24h after GnRH, the fertility of Nelore heifers is not influenced by the moment of the artificial insemination.

    KEY WORDS: Beef cattle, management, pregnancy test, ultrasound, sexing. Objetivou-se avaliar o efeito do momento da inseminação artificial (IA sobre a fertilidade e a proporção do sexo da cria de novilhas da raça Nelore (n = 200 submetidas a protocolo de IATF. As novilhas, distribuídas em cinco tratamentos (GC, GT6, GT12, GT18 e GT24, apresentavam idade média de 2,5 anos e peso médio de 342 kg. Realizaram-se as inseminações nos momentos 0 (GC, 6 (GT6, 12 (GT12, 18 (GT18 e 24 (GT24 horas após a aplicação do GnRH. As taxas de concepção foram de 87,5% (GC, 82,5% (GT6, 77,5% (GT12, 85,0% (GT18 e de 77,5% (GT24. Não houve diferença estatística (p>0,05 entre as taxas de

  14. Nutritional skewing of conceptus sex in sheep: effects of a maternal diet enriched in rumen-protected polyunsaturated fatty acids (PUFA

    Directory of Open Access Journals (Sweden)

    Williams Jim E

    2008-06-01

    Full Text Available Abstract Background Evolutionary theory suggests that in polygynous mammalian species females in better body condition should produce more sons than daughters. Few controlled studies have however tested this hypothesis and controversy exists as to whether body condition score or maternal diet is in fact the determining factor of offspring sex. Here, we examined whether maternal diet, specifically increased n-6 polyunsaturated fatty acid (PUFA intake, of ewes with a constant body condition score around the time of conception influenced sex ratio. Methods Ewes (n = 44 maintained in similar body condition throughout the study were assigned either a control (C diet or one (F enriched in rumen-protected PUFA, but otherwise essentially equivalent, from four weeks prior to breeding until d13 post-estrus. On d13, conceptuses were recovered, measured, cultured to assess their capacity for interferon-tau (IFNT production and their sex determined. The experiment was repeated with all ewes being fed the F diet to remove any effects of parity order on sex ratio. Maternal body condition score (BCS, plasma hormone and metabolite concentrations were also assessed throughout the study and related to diet. Results In total 129 conceptuses were recovered. Ewes on the F diet produced significantly more male than female conceptuses (proportion male = 0.69; deviation from expected ratio of 0.5, P 0.1, but positively correlated with maternal body condition score (P Conclusion These results provide evidence that maternal diet, in the form of increased amounts of rumen-protected PUFA fed around conception, rather than maternal body condition, can skew the sex ratio towards males. These observations may have implications to the livestock industry and animal management policies when offspring of one sex may be preferred over the other.

  15. Characterization of juvenile play in rats: importance of sex of self and sex of partner.

    Science.gov (United States)

    Argue, Kathryn J; McCarthy, Margaret M

    2015-01-01

    Juvenile social play is observed in many mammalian species, and its disruption in several neuropsychiatric disorders has greatly increased interest in understanding the origins and sources of variability in this behavior. We quantified social play behavior in juvenile rats and investigated the impact of sex and familiarity of the play partner. Sex differences in play behavior were investigated by comparing males and females from either same- or mixed-sex pairs with data pooled over 12 days of analysis. Whether play was altered based on the sex of the play partner was assessed using a paired analysis to compare play with a same- or opposite-sex play partner for both males and females. Additionally, a repeated measures design was utilized to determine whether play changed with increasing age. On postnatal day 33, a novel play partner was introduced. We used a repeated measures analysis to compare postnatal day 33 with the previous day. These approaches were used to assess the effects of age, sex, sex of partner, and familiarity of partner on total social play behavior as well as how play was broken down into components, such as pouncing, pinning, chasing, and boxing. There were sex differences in total frequency of play, and specific parameters of play behavior, such as chasing, pouncing, pinning, and boxing. Additionally, males significantly altered their play behavior in response to the sex of their play partner, whereas females were more sensitive to the familiarity of the play partner. This study provides critical groundwork for uncovering factors that regulate social play behavior and can be used to guide future mechanistic based work.

  16. Elusive Parnassius mnemosyne (Linnaeus, 1758) larvae: habitat selection, sex determination and sex ratio (Lepidoptera: Papilionidae)

    Czech Academy of Sciences Publication Activity Database

    Vlašánek, Petr; Bartoňová, Alena; Marec, František; Konvička, Martin

    2017-01-01

    Roč. 45, č. 180 (2017), s. 561-569 ISSN 0300-5267 R&D Projects: GA ČR GAP505/10/2167; GA AV ČR IAA600960925; GA ČR(CZ) GA17-13713S EU Projects: European Commission(XE) 669609 - Diversity6continents Institutional support: RVO:60077344 Keywords : Lepidoptera * Papilionidae * habitat Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Genetics and heredity (medical genetics to be 3) Impact factor: 0.264, year: 2016

  17. Improving repeatability by improving quality

    Energy Technology Data Exchange (ETDEWEB)

    Ronen, Shuki; Ackers, Mark; Schlumberger, Geco-Prakla; Brink, Mundy

    1998-12-31

    Time lapse (4-D) seismic is a promising tool for reservoir characterization and monitoring. The method is apparently simple: to acquire data repeatedly over the same reservoir, process and interpret the data sets, then changes between the data sets indicate changes in the reservoir. A problem with time lapse seismic data is that reservoirs are a relatively small part of the earth and important reservoir changes may cause very small differences to the time lapse data. The challenge is to acquire and process economical time lapse data such that reservoir changes can be detected above the noise of varying acquisition and environment. 7 refs., 9 figs.

  18. Telomerase Repeated Amplification Protocol (TRAP).

    Science.gov (United States)

    Mender, Ilgen; Shay, Jerry W

    2015-11-20

    Telomeres are found at the end of eukaryotic linear chromosomes, and proteins that bind to telomeres protect DNA from being recognized as double-strand breaks thus preventing end-to-end fusions (Griffith et al. , 1999). However, due to the end replication problem and other factors such as oxidative damage, the limited life span of cultured cells (Hayflick limit) results in progressive shortening of these protective structures (Hayflick and Moorhead, 1961; Olovnikov, 1973). The ribonucleoprotein enzyme complex telomerase-consisting of a protein catalytic component hTERT and a functional RNA component hTR or hTERC - counteracts telomere shortening by adding telomeric repeats to the end of chromosomes in ~90% of primary human tumors and in some transiently proliferating stem-like cells (Shay and Wright, 1996; Shay and Wright, 2001). This results in continuous proliferation of cells which is a hallmark of cancer. Therefore, telomere biology has a central role in aging, cancer progression/metastasis as well as targeted cancer therapies. There are commonly used methods in telomere biology such as Telomere Restriction Fragment (TRF) (Mender and Shay, 2015b), Telomere Repeat Amplification Protocol (TRAP) and Telomere dysfunction Induced Foci (TIF) analysis (Mender and Shay, 2015a). In this detailed protocol we describe Telomere Repeat Amplification Protocol (TRAP). The TRAP assay is a popular method to determine telomerase activity in mammalian cells and tissue samples (Kim et al. , 1994). The TRAP assay includes three steps: extension, amplification, and detection of telomerase products. In the extension step, telomeric repeats are added to the telomerase substrate (which is actually a non telomeric oligonucleotide, TS) by telomerase. In the amplification step, the extension products are amplified by the polymerase chain reaction (PCR) using specific primers (TS upstream primer and ACX downstream primer) and in the detection step, the presence or absence of telomerase is

  19. Coordinated hybrid automatic repeat request

    KAUST Repository

    Makki, Behrooz

    2014-11-01

    We develop a coordinated hybrid automatic repeat request (HARQ) approach. With the proposed scheme, if a user message is correctly decoded in the first HARQ rounds, its spectrum is allocated to other users, to improve the network outage probability and the users\\' fairness. The results, which are obtained for single- and multiple-antenna setups, demonstrate the efficiency of the proposed approach in different conditions. For instance, with a maximum of M retransmissions and single transmit/receive antennas, the diversity gain of a user increases from M to (J+1)(M-1)+1 where J is the number of users helping that user.

  20. Longevity enhances selection of environmental sex determination.

    Science.gov (United States)

    Bull, J J; Bulmer, M G

    1989-12-01

    Environmental sex determination (ESD) is a mechanism in which an individual develops as male or female largely in response to some environmental effect experienced early in life. Its forms range from sex determination by egg incubation temperature in reptiles to sex determination of photoperiod in amphipods. Previous theoretical work as suggested that ESD is favored by natural selection if the fitness consequences of the early environmental experience differ for males and females, so that an individual benefits by being male under some conditions and female under others. A drawback of ESD is that it enables climatic changes to influence the population sex ratio, and such fluctuations select against ESD. This study employed numerical analyses to investigate the balance between these two opposing forces. The negative impact of climatic fluctuations appears to depend greatly on species longevity: substantial between-year fluctuations are of little consequence in selecting against ESD in long-lived species because annual sex ratio fluctuations tend to cancel and thus alter the total population sex ratio only slightly. Thus, if a species is sufficiently long-lived, extreme ESD can be maintained despite only a weak advantage. This result offers one explanation for the failure to demonstrate an advantage for the extreme forms of ESD observed in reptiles.

  1. VVER-1000 dominance ratio

    International Nuclear Information System (INIS)

    Gorodkov, S.

    2009-01-01

    Dominance ratio, or more precisely, its closeness to unity, is important characteristic of large reactor. It allows evaluate beforehand the number of source iterations required in deterministic calculations of power spatial distribution. Or the minimal number of histories to be modeled for achievement of statistical error level desired in large core Monte Carlo calculations. In this work relatively simple approach for dominance ratio evaluation is proposed. It essentially uses core symmetry. Dependence of dominance ratio on neutron flux spatial distribution is demonstrated. (author)

  2. WWER-1000 dominance ratio

    International Nuclear Information System (INIS)

    Gorodkov, S.S.

    2009-01-01

    Dominance ratio, or more precisely, its closeness to unity, is important characteristic of large reactor. It allows evaluate beforehand the number of source iterations required in deterministic calculations of power spatial distribution. Or the minimal number of histories to be modeled for achievement of statistical error level desired in large core Monte Carlo calculations. In this work relatively simple approach for dominance ratio evaluation is proposed. It essentially uses core symmetry. Dependence of dominance ratio on neutron flux spatial distribution is demonstrated. (Authors)

  3. Sharpening Sharpe Ratios

    OpenAIRE

    William N. Goetzmann; Jonathan E. Ingersoll Jr.; Matthew I. Spiegel; Ivo Welch

    2002-01-01

    It is now well known that the Sharpe ratio and other related reward-to-risk measures may be manipulated with option-like strategies. In this paper we derive the general conditions for achieving the maximum expected Sharpe ratio. We derive static rules for achieving the maximum Sharpe ratio with two or more options, as well as a continuum of derivative contracts. The optimal strategy has a truncated right tail and a fat left tail. We also derive dynamic rules for increasing the Sharpe ratio. O...

  4. Selfish element maintains sex in natural populations of a parasitoid wasp.

    NARCIS (Netherlands)

    Stouthamer, R.; Tilborg, van M.; Jong, de J.H.; Nunney, L.; Luck, R.F.

    2001-01-01

    Genomic conflicts between heritable elements with different modes of inheritance are important in the maintenance of sex and in the evolution of sex ratio. Generally, we expect sexual populations to exhibit a 1:1 sex ratio. However, because of their biology, parasitoid wasps often exhibit a

  5. Sex Education: Another View

    Science.gov (United States)

    Hamilton, Jennifer

    1977-01-01

    The mother of a 14-year-old mentally retarded boy comments on the viewpoints of Dr. Sol Gordon (a sex education columnist) regarding masturbation, questions on sex, marriage, and the parents' role. (SBH)

  6. Evolution of heteromorphic sex chromosomes in the order Aulopiformes.

    Science.gov (United States)

    Ota, K; Kobayashi, T; Ueno, K; Gojobori, T

    2000-12-23

    The fish order Aulopiformes contains both synchronously hermaphroditic and gonochoristic species. From the cytogenetic viewpoint, few reports show that gonochoristic Aulopiformes have heteromorphic sex chromosomes. Because fish in this order give us a unique opportunity to elucidate the evolution of sex chromosomes, it is important to examine a phylogenetic relationship in Aulopiformes by both molecular evolutionary and cytogenetic methods. Thus, we conducted molecular phylogenetic and cytogenetic studies of six Aulopiform species. Our results suggested that hermaphroditic species were evolutionarily derived from gonochoristic species. It follows that the hermaphroditic species might have lost the heteromorphic sex chromosomes during evolution. Here, we suggest a possibility that heteromorphic sex chromosomes can disappear from the genome, even if they have appeared once in evolution. Taking into account Ohno's hypothesis that heteromorphic sex chromosomes might have emerged from autosomes, we propose the hypothesis that heteromorphic sex chromosomes may have undergone repeated events of appearance and disappearance during the course of fish evolution.

  7. Detecting isotopic ratio outliers

    International Nuclear Information System (INIS)

    Bayne, C.K.; Smith, D.H.

    1985-01-01

    An alternative method is proposed for improving isotopic ratio estimates. This method mathematically models pulse-count data and uses iterative reweighted Poisson regression to estimate model parameters to calculate the isotopic ratios. This computer-oriented approach provides theoretically better methods than conventional techniques to establish error limits and to identify outliers. 6 refs., 3 figs., 3 tabs

  8. Detecting isotopic ratio outliers

    Science.gov (United States)

    Bayne, C. K.; Smith, D. H.

    An alternative method is proposed for improving isotopic ratio estimates. This method mathematically models pulse-count data and uses iterative reweighted Poisson regression to estimate model parameters to calculate the isotopic ratios. This computer-oriented approach provides theoretically better methods than conventional techniques to establish error limits and to identify outliers.

  9. Detecting isotopic ratio outliers

    International Nuclear Information System (INIS)

    Bayne, C.K.; Smith, D.H.

    1986-01-01

    An alternative method is proposed for improving isotopic ratio estimates. This method mathematically models pulse-count data and uses iterative reweighted Poisson regression to estimate model parameters to calculate the isotopic ratios. This computer-oriented approach provides theoretically better methods than conventional techniques to establish error limits and to identify outliers

  10. Nonparametric additive regression for repeatedly measured data

    KAUST Repository

    Carroll, R. J.; Maity, A.; Mammen, E.; Yu, K.

    2009-01-01

    We develop an easily computed smooth backfitting algorithm for additive model fitting in repeated measures problems. Our methodology easily copes with various settings, such as when some covariates are the same over repeated response measurements

  11. Sex in situ

    DEFF Research Database (Denmark)

    Krøgholt, Ida

    2017-01-01

    Sex er en del af vores sociale praksis og centralt for det, vi hver især er. Men bortset fra pornoindustrien, har vi ikke mange muligheder for at få adgang til billeder af sex. Teater Nordkrafts forestilling Sex in situ vil gøre seksuelle billeder til noget, der kan deles, udveksles og tales om, og...

  12. Coeducation and Sex Roles.

    Science.gov (United States)

    Harris, Mary B.

    1986-01-01

    A study of the sex role stereotypes held by 538 first-term Australian university students from single-sex and coeducational high schools is presented. Results suggest that coeducational schooling may have some advantages for fostering interactions with the opposite sex. (MSE)

  13. sex and Cannibalism

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 12. The Secret Sex Lives of Rotifers Sex - sex and Cannibalism. T Ramakrishna Rao. General Article Volume 5 Issue 12 December 2000 pp 41-47. Fulltext. Click here to view fulltext PDF. Permanent link:

  14. REPEATABILITY OF FRUIT QUALITY TRAITS OF CACTUS PEAR

    Directory of Open Access Journals (Sweden)

    VALTÂNIA XAVIER NUNES

    2017-12-01

    Full Text Available ABSTRACT Repeatability analysis has been used to study traits in several crops, assisting in the definition of the minimum number needed to evaluate genotypes more efficiently and with less time and resource consumption. So far, however, no repeatability studies on cactus pear have been found in the literature. The objective of this study was to determine the coefficient of repeatability for cactus pear fruits traits and the minimum number of evaluations (fruit that can provide acceptable accuracy for the prediction of the true value. The experiment was conducted at the Federal Institute of Bahia/Campus Guanambi, with 150 fruits collected from three municipalities in the state of Bahia. The coefficients of repeatability were estimated by the methods of analysis of variance, principal components based on the covariance (PCCV and correlation (PCC matrices, and structural analysis based on the correlation matrix (SA. The analysis of variance showed that, except for fruit diameter, the effect of the production site (municipality was significant for all traits evaluated. The PCCV method was proven the most suitable for studying the repeatability of quality traits of cactus pear fruits. Seven fruits were required to determine, with 90% confidence, the traits length, diameter, fruit firmness, skin thickness, number of seeds, fruit mass, bark mass, pulp mass, pH, titratable acidity, soluble solids, SS/AT ratio, and pulp yield.

  15. Procreative liberty: the case for preconception sex selection.

    Science.gov (United States)

    Dahl, Edgar

    2003-01-01

    Preconception sex selection for non-medical reasons raises serious moral, legal and social issues. The main concerns include the threat of a sex ratio distortion due to a common preference for boys over girls, the charge of sexism, the danger of reinforcing gender stereotypical behaviour in sex selected children, and the fear of a slippery slope towards creating designer babies. This paper endeavours to show that none of the objections to preconception sex selection is conclusive and that there is no justification for denying parents the right to choose the sex of their prospective children.

  16. Topological characteristics of helical repeat proteins

    NARCIS (Netherlands)

    Groves, M R; Barford, D

    The recent elucidation of protein structures based upon repeating amino acid motifs, including the armadillo motif, the HEAT motif and tetratricopeptide repeats, reveals that they belong to the class of helical repeat proteins. These proteins share the common property of being assembled from tandem

  17. Digital storage of repeated signals

    International Nuclear Information System (INIS)

    Prozorov, S.P.

    1984-01-01

    An independent digital storage system designed for repeated signal discrimination from background noises is described. The signal averaging is performed off-line in the real time mode by means of multiple selection of the investigated signal and integration in each point. Digital values are added in a simple summator and the result is recorded the storage device with the volume of 1024X20 bit from where it can be output on an oscillograph, a plotter or transmitted to a compUter for subsequent processing. The described storage is reliable and simple device on one base of which the systems for the nuclear magnetic resonapce signal acquisition in different experiments are developed

  18. Hungarian repeat station survey, 2010

    Directory of Open Access Journals (Sweden)

    Péter Kovács

    2013-03-01

    Full Text Available The last Hungarian repeat station survey was completed between October 2010 and February 2011. Declination, inclination and the total field were observed using one-axial DMI fluxgate magnetometer mounted on Zeiss20A theodolite and GSM 19 Overhauser magnetometer. The magnetic elements of the sites were reduced to the epoch of 2010.5 on the basis of the continuous recordings of Tihany Geophysical Observatory. In stations located far from the reference observatory, the observations were carried out in the morning and afternoon in order to decrease the effect of the distant temporal correction. To further increase the accuracy, on-site dIdD variometer has also been installed near the Aggtelek station, in the Baradla cave, during the survey of the easternmost sites. The paper presents the technical details and the results of our last campaign. The improvement of the accuracy of the temporal reduction by the use of the local variometer is also reported.

  19. Linear Synchronous Motor Repeatability Tests

    International Nuclear Information System (INIS)

    Ward, C.R.

    2002-01-01

    A cart system using linear synchronous motors was being considered for the Plutonium Immobilization Plant (PIP). One of the applications in the PIP was the movement of a stack of furnace trays, filled with the waste form (pucks) from a stacking/unstacking station to several bottom loaded furnaces. A system was ordered to perform this function in the PIP Ceramic Prototype Test Facility (CPTF). This system was installed and started up in SRTC prior to being installed in the CPTF. The PIP was suspended and then canceled after the linear synchronous motor system was started up. This system was used to determine repeatability of a linear synchronous motor cart system for the Modern Pit Facility

  20. Two-dimensional quantum repeaters

    Science.gov (United States)

    Wallnöfer, J.; Zwerger, M.; Muschik, C.; Sangouard, N.; Dür, W.

    2016-11-01

    The endeavor to develop quantum networks gave rise to a rapidly developing field with far-reaching applications such as secure communication and the realization of distributed computing tasks. This ultimately calls for the creation of flexible multiuser structures that allow for quantum communication between arbitrary pairs of parties in the network and facilitate also multiuser applications. To address this challenge, we propose a two-dimensional quantum repeater architecture to establish long-distance entanglement shared between multiple communication partners in the presence of channel noise and imperfect local control operations. The scheme is based on the creation of self-similar multiqubit entanglement structures at growing scale, where variants of entanglement swapping and multiparty entanglement purification are combined to create high-fidelity entangled states. We show how such networks can be implemented using trapped ions in cavities.