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Sample records for repair item number

  1. Closed loop two-echelon repairable item systems

    NARCIS (Netherlands)

    Spanjers, L.; van Ommeren, Jan C.W.; Zijm, Willem H.M.

    In this paper we consider closed loop two-echelon repairable item systems with repair facilities both at a number of local service centers (called bases) and at a central location (the depot). The goal of the system is to maintain a number of production facilities (one at each base) in optimal

  2. Closed loop two-echelon repairable item systems

    NARCIS (Netherlands)

    Spanjers, L.; van Ommeren, Jan C.W.; Zijm, Willem H.M.; Liberopoulos, G.; Papadopoulos, C.T.; Tan, B.; MacGregor Smith, J.; Gershwin, S.B.

    2006-01-01

    In this paper we consider closed loop two-echelon epairable item systems with repair facilities both at a number of local service centers (called bases) and at a central location (the depot). The goal of the system is to maintain a number of production facilities (one at each base) in optimal

  3. Interim Report of Field Test of Expedient Pavement Repairs (Test Items 1-15).

    Science.gov (United States)

    1980-03-01

    OF FIELD TEST OFEXPEDIENT PAVEMENT REPAIRS ( TEST ITEMS 1-15). RAYMONDS.4OLLINGS lWGINE E :AH1 DIVISION .I MARŜ 6 // il) JNTEIM REPUT TiJUL1077...Pavement Repairs ( Test Items 1-15) 6 PERFORMING ORG. REPORT NUMBER 7. AUTHOR(&) S. CONTRACT OR GRANT NUMBER(&) Raymond S. Rollings 9. PERFORMING...21 Item 14 Test Results .................... 33 22 Density Results, Item 15....................34 23 Summary of Test Items ......................37 24

  4. Field Test of Expedient Pavement Repairs (Test Items 16-35).

    Science.gov (United States)

    1980-11-01

    7 AD-AlG 903 A IR FORCE ENGINEERING AND SERVICES CENTER TYNDALL AF--ETC FG 13/2 FIELD TEST OF EXPEDIENT PAVEMENT REPAIRS ( TEST ITEMS 16-35).(U...PAVEMENT REPAIRS ~( TEST ITEMS 16-35) MICHAEL T. McNERNEY ENGINEERING RESEARCH DIVISION NOVEMBER 1980 ’ FINAL REPORT JULY 1978 - SEPTEMBER 1979 APPROVED FOR...EXPEDIENT PAVEMENT REPAIRS Final Reportg- July 1978- ( TEST ITEMS 16-35), Segtr W79 7. "AUTHOR(s) 8 CONTRACT OR GRANT NUMBER(s) Michael T./lcNernev, P

  5. Capacitated two-indenture models for repairable item systems

    NARCIS (Netherlands)

    Zijm, Willem H.M.; Avsar, Zeynep Müge

    2003-01-01

    A two-indenture maintenance system is considered for a number of identical installations, in use at a single site. The installations are considered as assemblies that are made up of a number of repairable components. A component repair center and an assembly facility are both modeled as product form

  6. Capacitated two-indenture models for repairable item systems

    NARCIS (Netherlands)

    Zijm, Willem H.M.; Avsar, Z.M.; van Houtum, Geert-Jan

    2001-01-01

    A two-indenture maintenance system is considered for a number of identical installations, in use at a single site. The installations are considered as assemblies that are made up of a number of repairable components. A component repair center and an assembly facility are both modeled as product form

  7. Capacitated two-echelon inventory models for repairable item systems

    NARCIS (Netherlands)

    Avsar, Z.M.; Zijm, Willem H.M.; Gershwin, S.B.; Dallery, Y.; Papadopoulos, C.; Smith, J.M.

    2002-01-01

    In this paper, we consider two-echelon maintenance systems with repair facilities both at a number of local service centers (called bases) and at a central location. Each repair facility may be considered to be a job shop and is modeled as a (limited capacity) open queuing network, while any

  8. Soviet Cybernetics: Recent News Items, Number Thirteen.

    Science.gov (United States)

    Holland, Wade B.

    An issue of "Soviet Cybernetics: Recent News Items" consists of English translations of the leading recent Soviet contributions to the study of cybernetics. Articles deal with cybernetics in the 21st Century; the Soviet State Committee on Science and Technology; economic reforms in Rudnev's ministry; an interview with Rudnev; Dnepr-2; Dnepr-2…

  9. An EPQ model with imperfect items using interval grey numbers

    Directory of Open Access Journals (Sweden)

    Erdal Aydemir

    2015-01-01

    Full Text Available The classic economic production quantity (EPQ model has been widely used to determine the optimal production quantity. However, the analysis for finding an EPQ model has many weaknesses which lead many researchers and practitioners to make extensions in several aspects on the original EPQ model. The basic assumption of EPQ model is that 100% of manufactured products are non-defective that is not valid for many production processes generally. The purpose of this paper is to develop an EPQ model with grey demand rate and cost values with maximum backorder level allowed with the good quality items in units under an imperfect production process. The imperfect items are considered to be low quality items which are sold to a particular purchaser at a lower price and, the others are reworked and scrapped. A mathematical model is developed and then an industrial example is presented on the wooden chipboard production process for illustration of the proposed model.

  10. The Tipping Point: F-Score as a Function of the Number of Retrieved Items

    DEFF Research Database (Denmark)

    Guns, Raf; Lioma, Christina; Larsen, Birger

    2012-01-01

    One of the best known measures of information retrieval (IR) performance is the F-score, the harmonic mean of precision and recall. In this article we show that the curve of the F-score as a function of the number of retrieved items is always of the same shape: a fast concave increase to a maximum......, followed by a slow decrease. In other words, there exists a single maximum, referred to as the tipping point, where the retrieval situation is 'ideal' in terms of the F-score. The tipping point thus indicates the optimal number of items to be retrieved, with more or less items resulting in a lower F...

  11. Retrieval of very large numbers of items in the Web of Science: an exercise to develop accurate search strategies

    NARCIS (Netherlands)

    Arencibia-Jorge, R.; Leydesdorff, L.; Chinchilla-Rodríguez, Z.; Rousseau, R.; Paris, S.W.

    2009-01-01

    The Web of Science interface counts at most 100,000 retrieved items from a single query. If the query results in a dataset containing more than 100,000 items the number of retrieved items is indicated as >100,000. The problem studied here is how to find the exact number of items in a query that lead

  12. The Tipping Point: F-Score as a Function of the Number of Retrieved Items

    DEFF Research Database (Denmark)

    Guns, Raf; Lioma, Christina; Larsen, Birger

    2012-01-01

    One of the best known measures of information retrieval (IR) performance is the F-score, the harmonic mean of precision and recall. In this article we show that the curve of the F-score as a function of the number of retrieved items is always of the same shape: a fast concave increase to a maximu...

  13. Memory for melodies in unfamiliar tuning systems: Investigating effects of recency and number of intervening items.

    Science.gov (United States)

    Herff, Steffen A; Olsen, Kirk N; Dean, Roger T; Prince, Jon

    2017-05-26

    In a continuous recognition paradigm, most stimuli elicit superior recognition performance when the item to be recognised is the most recent stimulus (a recency-in-memory effect). Furthermore, increasing the number of intervening items cumulatively disrupts memory in most domains. Memory for melodies composed in familiar tuning systems also shows superior recognition for the most recent melody, but no disruptive effects from the number of intervening melodies. A possible explanation has been offered in a novel regenerative multiple representations (RMR) conjecture. The RMR assumes that prior knowledge informs perception and perception influences memory representations. It postulates that melodies are perceived, thus also represented, simultaneously as integrated entities and also their components (such as pitches, pitch intervals, short phrases, and rhythm). Multiple representations of the melody components and melody as a whole can restore one another, thus providing resilience against disruptive effects from intervening items. The conjecture predicts that melodies in an unfamiliar tuning system are not perceived as integrated melodies and should: a) disrupt recency-in-memory advantages; and b) facilitate disruptive effects from the number of intervening items. We test these two predictions in three experiments. Experiments 1 and 2 show that no recency-in-memory effects emerge for melodies in an unfamiliar tuning system. In Experiment 3, disruptive effects occurred as the number of intervening items and unfamiliarity of the stimuli increased. Overall, results are coherent with the predictions of the RMR conjecture. Further investigation of the conjecture's predictions may lead to greater understanding of the fundamental relationships between memory, perception, and behavior.

  14. The number of objects determines visual working memory capacity allocation for complex items.

    Science.gov (United States)

    Balaban, Halely; Luria, Roy

    2015-10-01

    The goal of the present study was to examine whether visual working memory (WM) capacity allocation is determined solely by complexity, with the number of objects being redundant, as suggested by flexible resource models. Participants performed the change detection task with random polygons as stimuli, while we monitored the contralateral delay activity (CDA), an electrophysiological marker whose amplitude rises as WM load increases. In Experiment 1, we compared the WM maintenance of one whole polygon to a single half of the polygon, equating the number of items but varying the complexity level. Additionally, we compared the whole polygon to two halves of a polygon, thus roughly equating perceptual complexity but manipulating the number of items. The results suggested that only the number of objects determined WM capacity allocation: the CDA was identical when comparing one whole polygon to one polygon half, even though these conditions differed in complexity. Furthermore, the CDA amplitude was lower in the whole polygon condition relative to the two halves condition, even though both contained roughly the same amount of information. Experiment 2 extended these results by showing that two polygon halves that moved separately but then met and moved together were gradually integrated to consume similar WM capacity as one polygon half. Additionally, in both experiments we found an object benefit in accuracy, corroborating the important role of objects in WM. Our results demonstrate that WM capacity allocation cannot be explained by complexity alone. Instead, it is highly sensitive to objecthood, as suggested by discrete slot models.

  15. The Effects of the Number of Options per Item and Student Ability on Test Validity and Reliability.

    Science.gov (United States)

    Trevisan, Michael S.; And Others

    1991-01-01

    The reliability and validity of multiple-choice tests were computed as a function of the number of options per item and student ability for 435 parochial high school juniors, who were administered the Washington Pre-College Test Battery. Results suggest the efficacy of the three-option item. (SLD)

  16. Packing a bin online to maximize the total number of items

    NARCIS (Netherlands)

    Faigle, U.; Kern, Walter

    1996-01-01

    A bin of capacity 1 and a nite sequence of items of sizes a1; a2; : : : are considered, where the items are given one by one without information about the future. An online algorithm A must irrevocably decide whether or not to put an item into the bin whenever it is presented. The goal is to

  17. Estimating quasi-loglinear models for a Rasch table if the numbers of items is large

    NARCIS (Netherlands)

    Kelderman, Henk

    1987-01-01

    The Rasch Model and various extensions of this model can be formulated as a quasi loglinear model for the incomplete subgroup x score x item response 1 x ... x item response k contingency table. By comparing various loglinear models, specific deviations of the Rasch model can be tested. Parameter es

  18. Quantification of DNA repair protein kinetics after γ-irradiation using number and brightness analysis

    Science.gov (United States)

    Abdisalaam, Salim; Poudel, Milan; Chen, David J.; Alexandrakis, George

    2011-03-01

    The kinetics of most proteins involved in DNA damage sensing, signaling and repair following ionizing radiation exposure cannot be quantified by current live cell fluorescence microscopy methods. This is because most of these proteins, with only few notable exceptions, do not attach in large numbers at DNA damage sites to form easily detectable foci in microscopy images. As a result a high fluorescence background from freely moving and immobile fluorescent proteins in the nucleus masks the aggregation of proteins at sparse DNA damage sites. Currently, the kinetics of these repair proteins are studied by laser-induced damage and Fluorescence Recovery After Photobleaching that rely on the detectability of high fluorescence intensity spots of clustered DNA damage. We report on the use of Number and Brightness (N&B) analysis methods as a means to monitor kinetics of DNA repair proteins during sparse DNA damage created by γ-irradiation, which is more relevant to cancer treatment than laser-induced clustered damage. We use two key double strand break repair proteins, namely Ku 70/80 and the DNA-dependent protein kinase catalytic subunit (DNA-PKCS), as specific examples to showcase the feasibility of the proposed methods to quantify dose-dependent kinetics for DNA repair proteins after exposure to γ-rays.

  19. Influence of proportional number relationships on item accessibility and students' strategies

    Science.gov (United States)

    Carney, Michele B.; Smith, Everett; Hughes, Gwyneth R.; Brendefur, Jonathan L.; Crawford, Angela

    2016-12-01

    Proportional reasoning is important to students' future success in mathematics and science endeavors. More specifically, students' fluent and flexible use of scalar and functional relationships to solve problems is critical to their ability to reason proportionally. The purpose of this study is to investigate the influence of systematically manipulating the location of an integer multiplier—to press the scalar or functional relationship—on item difficulty and student solution strategies. We administered short-answer assessment forms to 473 students in grades 6-8 (approximate ages 11-14) and analyzed the data quantitatively with the Rasch model to examine item accessibility and qualitatively to examine student solution strategies. We found that manipulating the location of the integer multiplier encouraged students to make use of different aspects of proportional relationships without decreasing item accessibility. Implications for proportional reasoning curricular materials, instruction, and assessment are addressed.

  20. Variance Difference between Maximum Likelihood Estimation Method and Expected A Posteriori Estimation Method Viewed from Number of Test Items

    Science.gov (United States)

    Mahmud, Jumailiyah; Sutikno, Muzayanah; Naga, Dali S.

    2016-01-01

    The aim of this study is to determine variance difference between maximum likelihood and expected A posteriori estimation methods viewed from number of test items of aptitude test. The variance presents an accuracy generated by both maximum likelihood and Bayes estimation methods. The test consists of three subtests, each with 40 multiple-choice…

  1. Estimating the Optimum Number of Options per Item Using an Incremental Option Paradigm.

    Science.gov (United States)

    Trevisan, Michael S.; And Others

    1994-01-01

    The reliabilities of 2-, 3-, 4-, and 5-choice tests were compared through an incremental-option model on a test taken by 154 high school seniors. Creating the test forms incrementally more closely approximates actual test construction. The nonsignificant differences among the option choices support the three-option item. (SLD)

  2. The Proposal of Demand Estimation of Repairable Items for the Weapon Systems During the Initial Support Period: F-16 Case Study

    Directory of Open Access Journals (Sweden)

    Bahtiyar Eren

    2012-02-01

    Full Text Available Every country that has military systems such as aircraft, radar, warship or tank has to meet the operational needs of those military systems in order to keep them ready for military operations. Logistics support needs are defined basically either before or after procurement. If they are defined before procurement, they are called "initial support requirement", otherwise called "sustainment support requirement". Due to the fact that new system will be added into the Turkish military inventory, it is focused on the initial support requirement phase. In addition to that, it is focused on repairable items since most of the material acquisition cost within the initial support budget is allocated to repairable items. In this study, within the scope of initial support requirements,the method that produces much better results in terms of quantity and cost perspective than the ones used in Turkey and USA is established and demonstrated by using real data set of F-16.

  3. Reducing the item number to obtain the same-length self-assessment scales: a systematic approach using result of graphical loglinear rasch models

    DEFF Research Database (Denmark)

    Nielsen, Tine; Kreiner, Svend

    2011-01-01

    approach to item reduction based on results of graphical loglinear Rasch modeling (GLLRM) was designed. This approach was then used to reduce the number of items in the subscales of the R-D-LSI which had an item-length of more than seven items, thereby obtaining the Danish Self-Assessment Learning Styles......The Revised Danish Learning Styles Inventory (R-D-LSI) (Nielsen 2005), which is an adaptation of Sternberg- Wagner Thinking Styles Inventory (Sternberg, 1997), comprises 14 subscales, each measuring a separate learning style. Of these 14 subscales, 9 are eight items long and 5 are seven items long...

  4. Generalization of the Lord-Wingersky Algorithm to Computing the Distribution of Summed Test Scores Based on Real-Number Item Scores

    Science.gov (United States)

    Kim, Seonghoon

    2013-01-01

    With known item response theory (IRT) item parameters, Lord and Wingersky provided a recursive algorithm for computing the conditional frequency distribution of number-correct test scores, given proficiency. This article presents a generalized algorithm for computing the conditional distribution of summed test scores involving real-number item…

  5. 41 CFR 101-26.301-2 - Issue of used, repaired, and rehabilitated items in serviceable condition.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Issue of used, repaired... and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26-PROCUREMENT SOURCES AND PROGRAM 26.3-Procurement of GSA Stock...

  6. Controle on-line da taxa média de defeitos por item produzido numa produção finita on-line process control of the average number of defects per item in a short run production

    Directory of Open Access Journals (Sweden)

    Carla Simone de Lima Teixeira

    2013-01-01

    Full Text Available Este trabalho propõe uma abordagem para monitoramento da taxa média de defeitos por item produzido numa produção finita ou encomenda de N itens. A cada ciclo de m itens produzidos, inspecionam-se os últimos r itens. Em cada item inspecionado conta-se o número de defeitos e cada item é classificado como aprovado se o número de defeitos satisfizer o critério do limite de controle. Se todos os r itens forem aprovados, a produção continua, caso contrário interrompe-se a produção à procura de causas especiais. Os itens inspecionados são descartados somente quando há parada no processo. Após a produção de N itens, um lote adicional será produzido para completar a quantia encomendada, mas esses não passarão por inspeção. Será utilizada uma cadeia de Markov finita de estados discretos para determinar as probabilidades de mudança de estado. Elas são utilizadas nas expressões de custo para determinar a estratégia ótima de monitoração, que será obtida através da otimização de três parâmetros: intervalo amostral (m, tamanho da amostra retrospectiva (r e o limite de controle (LC. Os parâmetros serão obtidos através de busca direta, de forma que se minimize a expressão do custo médio por item produzido. Um exemplo numérico ilustra a proposta.This paper proposes an approach for monitoring the average number of non-conformities per items in short-run productions of N items. After every m produced items, the last r items are inspected. For each inspected item, the number of defects is counted; each inspected item is classified as approved if it meets the control limit criterion. If all r inspected items are approved, then the production goes on, otherwise it is stopped for adjustment. The inspected items are all discarded in case of production stoppage. After a production of N items, an additional lot is produced to complete the size ordered, but this additional lot does suffer inspection. A finite discrete state

  7. Retrieval of very large numbers of items in the Web of Science: an exercise to develop accurate search strategies

    CERN Document Server

    Arencibia-Jorge, Ricardo; Chinchilla-Rodriguez, Zaida; Rousseau, Ronald; Paris, Soren W

    2009-01-01

    The current communication presents a simple exercise with the aim of solving a singular problem: the retrieval of extremely large amounts of items in the Web of Science interface. As it is known, Web of Science interface allows a user to obtain at most 100,000 items from a single query. But what about queries that achieve a result of more than 100,000 items? The exercise developed one possible way to achieve this objective. The case study is the retrieval of the entire scientific production from the United States in a specific year. Different sections of items were retrieved using the field Source of the database. Then, a simple Boolean statement was created with the aim of eliminating overlapping and to improve the accuracy of the search strategy. The importance of team work in the development of advanced search strategies was noted.

  8. Effect of reducing the number of items of the Oral Health Impact Profile on responsiveness, validity and reliability in edentulous populations.

    Science.gov (United States)

    Awad, Manal; Al-Shamrany, Muneera; Locker, David; Allen, Finbarr; Feine, Jocelyne

    2008-02-01

    The 49-item Oral Health Impact Profile (OHIP) has shown strong responsiveness, reliability and validity. However, the large number of items included may limit its use in clinical trials, clinical practice and surveys. The main objective of this study is to assess the effect of reducing the number of items in each domain, one at a time, on responsiveness, reliability and validity of the OHIP in edentulous populations. Data used in this study were obtained from two randomized clinical trials comparing mandibular implant overdentures and conventional dentures among 102 subjects between 35 and 65 years of age, and 60 subjects over the age of 65 years. Participants were edentulous individuals who wished to replace their current prostheses. Subjects in both trials were asked to complete the 49-item OHIP prior to treatment and at 2 months post-treatment. Within the study, effect sizes were computed at each stage of item reduction using the impact method. Intraclass correlation coefficients and Pearson's correlation coefficients were also assessed at each stage of item reduction. In addition, receiver-operating characteristic (ROC) curves were used to indicate the accuracy with which measurement changes corresponded to judgements of important changes in Oral Health Related Quality of Life (OHRQL). The results indicated that, in general, domain responsiveness was not affected by the reduction of the number of items used per domain. However, there was a decrease in reliability, especially within the 'psychological' and 'social' disabilities and 'handicap' domains (35- to 65-year group). In addition, there was a decrease in construct validity of the 'physical pain', 'psychological' and 'social disabilities' domains (35- to 65-year group), as well as on 'physical pain', 'psychological discomfort', 'physical' and 'psychological' disabilities in the 65-year and older group. This occurred primarily, when reducing from two to one item per domain. Among the 35- to 65-year group

  9. ADJUSTMENT, MAINTENANCE, AND REPAIR OF CROP HARVESTING MACHINERY. AGRICULTURAL MACHINERY--SERVICE OCCUPATIONS, MODULE NUMBER 11.

    Science.gov (United States)

    Ohio State Univ., Columbus. Center for Vocational and Technical Education.

    ONE OF A SERIES DESIGNED FOR HELPING TEACHERS PREPARE POSTSECONDARY-LEVEL STUDENTS FOR AGRICULTURAL MACHINERY SERVICE OCCUPATIONS AS PARTS MEN, MECHANICS, MECHANIC'S HELPERS, AND SERVICE SUPERVISORS, THIS GUIDE AIMS TO DEVELOP STUDENT COMPETENCY IN ADJUSTING, REPAIRING, AND MAINTAINING CROP HARVESTING MACHINERY. SUGGESTIONS FOR INTRODUCTION OF THE…

  10. ADJUSTMENT, MAINTENANCE, AND REPAIR OF SMALL GASOLINE ENGINES. AGRICULTURAL MACHINERY--SERVICE OCCUPATIONS, MODULE NUMBER 12.

    Science.gov (United States)

    Ohio State Univ., Columbus. Center for Vocational and Technical Education.

    ONE OF A SERIES DESIGNED TO HELP TEACHERS PREPARE POSTSECONDARY STUDENTS FOR THE AGRICULTURAL MACHINERY SERVICE OCCUPATIONS AS PARTS MEN, MECHANICS, MECHANIC'S HELPERS, OR SERVICE SUPERVISORS, THIS GUIDE AIMS TO DEVELOP STUDENT COMPETENCY IN THE ADJUSTMENT, MAINTENANCE, AND REPAIR OF SMALL GASOLINE ENGINES. IT WAS DEVELOPED BY A NATIONAL TASK…

  11. Biomechanical evaluation of varying the number of loops in a repair of a physiological model of Achilles tendon rupture.

    Science.gov (United States)

    Grieco, Preston W; Frumberg, David B; Weinberg, Maxwell; Pivec, Robert; Naziri, Qais; Uribe, Jaime A

    2015-04-01

    Numerous suturing techniques have been described to treat Achilles tendon ruptures. No prior studies have evaluated frayed tendon ends on construct strength and whether this allows for less extensile exposure. Forty bovine Achilles tendons were divided into groups: 1 control and 4 experimental. Experimental groups were sectioned with ends frayed longitudinally in 2 mm intervals for 2 cm with no fraying for the control group. Four-stand Krackow sutures were used for repairs with 3 loops in the control group, 2 loops in frayed section for experimental groups, and varying numbers of loops (1-4) in healthy tendon. Samples were tested in loading cells at 100 N and 190 N for 1000 cycles. Gap width and maximum load failure were measured. Gapping was tendon (10.9-13.9 mm). Most early catastrophic failures (5/8) occurred in groups with 1-2 loops in healthy tendon. Two failures at 100 N occurred in 1-loop healthy tendons. The least failures occurred in controls (2/8), at 190 N. Suture loops incorporated into frayed tendon portions predisposed repairs to significantly greater gapping and lower maximal failure forces than 4-strand Krackow repairs in unfrayed tendons. We cannot recommend attempting more limited exposures with sutures in frayed tendon as this may lead to early repair failure. We provided a physiologic model utilizing frayed tendon ends that resembles in vivo Achilles tendon rupture. © The Author(s) 2014.

  12. There is no number effect in the licensing of negative polarity items : a reply to Guerzoni and Sharvit

    NARCIS (Netherlands)

    Hoeksema, Jack

    2008-01-01

    Guerzoni and Sharvit (Linguistics and Philosophy 30:361-391, 2007) provide an argument that plural, but not singular, wh-phrases may contain a negative polarity item in their restriction, and connect this with the semantic property of exhaustivity. I will show that this claim is factually incorrect,

  13. Increasing the Number of Replications in Item Response Theory Simulations: Automation through SAS and Disk Operating System

    Science.gov (United States)

    Gagne, Phill; Furlow, Carolyn; Ross, Terris

    2009-01-01

    In item response theory (IRT) simulation research, it is often necessary to use one software package for data generation and a second software package to conduct the IRT analysis. Because this can substantially slow down the simulation process, it is sometimes offered as a justification for using very few replications. This article provides…

  14. Increasing the Number of Replications in Item Response Theory Simulations: Automation through SAS and Disk Operating System

    Science.gov (United States)

    Gagne, Phill; Furlow, Carolyn; Ross, Terris

    2009-01-01

    In item response theory (IRT) simulation research, it is often necessary to use one software package for data generation and a second software package to conduct the IRT analysis. Because this can substantially slow down the simulation process, it is sometimes offered as a justification for using very few replications. This article provides…

  15. Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

    DEFF Research Database (Denmark)

    Sønderstrup, Ida Marie Heeholm; Nygård, Sune Boris; Poulsen, Tim Svenstrup

    2015-01-01

    (MMR) subtypes of CRC have been associated with benefit from adjuvant chemotherapy of primary CRC. Given the involvement of the topoisomerase enzymes in DNA replication and repair, we raised the hypothesis that an association may exist between TOP gene copy numbers and MMR proficiency/deficiency in CRC...... patients with deficient MMR (dMMR) CRC. TOP1 and TOP2A gene copy numbers and their ratios per nucleus were correlated with MMR status using the Mann-Whitney test. Validation cohort: FFPE samples from 154 patients with primary stage III CRC (originally included in the RANX05 study) were classified according...

  16. Validation of the Algorithms for Base Exchangeable Repair Costs (Engine) and Base Exchangeable Modification Costs (Engine) for the Component Support Cost System (D160B).

    Science.gov (United States)

    2014-09-26

    REPORTING 010 03 NUMBER. ITEM IDENTIFICATION Oil 03 NOMENCLATURE . ITEM 012 03 PRICE. STANDARD INVENTORY 013 03 CODE, WEAPON SYSTEM SUPPORT 014 05 CODE...elements not used in calculation of standard depot repair prices (* sales prices"). ISI affirms the congruence of the definitions of repair prices as

  17. Brain activity is related to individual differences in the number of items stored in auditory short-term memory for pitch: evidence from magnetoencephalography.

    Science.gov (United States)

    Grimault, Stephan; Nolden, Sophie; Lefebvre, Christine; Vachon, François; Hyde, Krista; Peretz, Isabelle; Zatorre, Robert; Robitaille, Nicolas; Jolicoeur, Pierre

    2014-07-01

    We used magnetoencephalography (MEG) to examine brain activity related to the maintenance of non-verbal pitch information in auditory short-term memory (ASTM). We focused on brain activity that increased with the number of items effectively held in memory by the participants during the retention interval of an auditory memory task. We used very simple acoustic materials (i.e., pure tones that varied in pitch) that minimized activation from non-ASTM related systems. MEG revealed neural activity in frontal, temporal, and parietal cortices that increased with a greater number of items effectively held in memory by the participants during the maintenance of pitch representations in ASTM. The present results reinforce the functional role of frontal and temporal cortices in the retention of pitch information in ASTM. This is the first MEG study to provide both fine spatial localization and temporal resolution on the neural mechanisms of non-verbal ASTM for pitch in relation to individual differences in the capacity of ASTM. This research contributes to a comprehensive understanding of the mechanisms mediating the representation and maintenance of basic non-verbal auditory features in the human brain.

  18. A change in the number of CCSP(pos)/SPC(pos) cells in mouse lung during development, growth, and repair.

    Science.gov (United States)

    Sun, Ruowen; Zhou, Qiliang; Ye, Xulu; Takahata, Takenori; Ishiguro, Atsushi; Kijima, Hiroshi; Nukiwa, Toshihiro; Saijo, Yasuo

    2013-12-01

    Putative resident stem/progenitor cells have been identified in the bronchoalveolar duct junction (BADJ) of the murine lung. However, the contribution of stem cells expressing both Clara cell secretory protein (CCSP) and pro-surfactant protein C (SP-C) to the repair and maintenance of normal homeostasis is still unclear. In this study, we identified and then quantified CD45(neg)/CCSP(pos)/SP-C(pos) cell numbers in normal and lung-injured mice. Normal lung tissues of fetal, newborn, and adult mice were used to evaluate lung progenitor cells during development and growth. Mice treated with naphthalene were used for the bronchiolar epithelium injury model, and mice treated with bleomycin were used for the alveolar epithelium injury model. These lung tissues were stained with CD45, CCSP, and SP-C antibodies by immunofluorescence. The number of lung progenitor cells was counted as CD45(neg)/CCSP(pos)/SP-C(pos) cells by flow cytometry. CCSP(pos)/SP-C(pos) epithelial cells in the BADJ were identified from E18 to 7 months after birth. The percentage of CD45(neg)/CCSP(pos)/SP-C(pos) cells was relatively stable to 7 months (between 0.3±0.04% and 1.28±0.11%). When lungs were treated with naphthalene, the proliferation of CCSP(pos)/SP-C(pos) cells was observed as patches of double-positive cells and preceded the recovery of bronchioles. In contrast, when lungs were treated with bleomycin, the proliferation of CCSP(pos)/SP-C(pos) cells was observed, but the type II alveolar epithelial cells never recovered to baseline. CCSP(pos)/SP-C(pos) lung cells were stable until 7 months after birth. These cells in the BADJ primarily regenerate bronchiolar epithelial cells and not alveolar epithelial cells. Copyright © 2013 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

  19. Computerized adaptive testing with item cloning

    NARCIS (Netherlands)

    Glas, Cornelis A.W.; van der Linden, Willem J.

    2003-01-01

    To increase the number of items available for adaptive testing and reduce the cost of item writing, the use of techniques of item cloning has been proposed. An important consequence of item cloning is possible variability between the item parameters. To deal with this variability, a multilevel item

  20. PROMOTING THE MANAGEMENT LEVEL TO PLAY SUPPORTING ROLE IN SPECIAL ITEMS FOR REPAIR AND PURCHASE%提升管理水平 发挥修购专项重要支撑作用

    Institute of Scientific and Technical Information of China (English)

    李金祥

    2011-01-01

    文章分析了修购专项对科研单位重要的支撑作用,总结了修购专项组管理取得的经验:一是健全制度体系,二是优化管理流程,三是推进预算执行,四是开展专项培训,五是运用先进手段,提高工作效率。最后指出下一步修购专项工作计划。%This paper analyzed the important supporting role of special items for repair and purchase in scientific research institutes,summarized the experience in the management,i.e.,to perfect the institution system,to optimize the management process,to promote implement of budget,to carry out training,and to use the advanced methods.Finally,it pointed out the work plan on special items.

  1. Item Overexposure in Computerized Classification Tests Using Sequential Item Selection

    Directory of Open Access Journals (Sweden)

    Alan Huebner

    2012-06-01

    Full Text Available Computerized classification tests (CCTs often use sequential item selection which administers items according to maximizing psychometric information at a cut point demarcating passing and failing scores. This paper illustrates why this method of item selection leads to the overexposure of a significant number of items, and the performances of three different methods for controlling maximum item exposure rates in CCTs are compared. Specifically, the Sympson-Hetter, restricted, and item eligibility methods are examined in two studies realistically simulating different types of CCTs and are evaluated based upon criteria including classification accuracy, the number of items exceeding the desired maximum exposure rate, and test overlap. The pros and cons of each method are discussed from a practical perspective.

  2. When "Other" Initiate Repair.

    Science.gov (United States)

    Schegloff, Emanuel A.

    2000-01-01

    Elaborates on the locus of other-initiated repair, and reports on a number of environments in which others initiate repair turns later than the one directly following the trouble-source turn. Describes several ways that other initiation of repair, which occurs in next-turn position, may be delayed within that position. (Author/VWL)

  3. Study of Match Fit between Passage and Item Numbers on Reading Comprehension Subsection of Chinese Proficiency Test%阅读理解考试篇章数量与题目数量拟合度研究

    Institute of Scientific and Technical Information of China (English)

    柴省三

    2014-01-01

    阅读篇章的选择、多项选择题目的设计以及篇章数量与测验题目数量的拟合度问题,是影响阅读理解能力测试信度和效度的基本因素。篇章数量和题目数量的不同组合方式对阅读理解测验误差和信度的影响也不相同。本研究以中国汉语水平考试(HSK)的实测数据为基础,随机选择500名考生作为研究样本,借助概化理论的随机双面嵌套(nested)设计s×(i:p)分析了HSK阅读理解测验中的误差来源和结构,对篇章数量和题目数量的匹配合理性进行了检验。研究结果显示:增加文章数量和题目数量均可以提高测验的精度,但增加文章数量比增加题目数量对概化系数(Generalizability coefficient, Eρ2)的提高作用更有效;HSK阅读理解测验的篇章数量和题目数量的现行组合方式符合误差控制的原则和信度指标的要求。%The selection of passages, the design of multiple choice items based on the passages and match fit between passage and item numbers are among the most important factors affecting reading comprehension test reliability and validity. This study applied generalizability theory to investigate the relative contributions of test-takers, items and passages to the score dependability of the Chinese Proficiency Test (HSK). The study sampled 500 test takers from total of 7238 participants in the HSK generic data set which was administered in the April 2011 of the China mainland. The analysis isolated the variance components due to persons, items and passages, and their effects on the dependability. The research indicated that the main effect component that took the largest share of variance was the items within a passage;the increase of passage numbers contributed more than that of the item numbers did for the generalizability coefficient (Eρ2). The findings taken together prove that the match of the passage and item numbers in the HSK is desirable for

  4. Estimating Latent Variable Interactions with the Unconstrained Approach: A Comparison of Methods to Form Product Indicators for Large, Unequal Numbers of Items

    Science.gov (United States)

    Jackman, M. Grace-Anne; Leite, Walter L.; Cochrane, David J.

    2011-01-01

    This Monte Carlo simulation study investigated methods of forming product indicators for the unconstrained approach for latent variable interaction estimation when the exogenous factors are measured by large and unequal numbers of indicators. Product indicators were created based on multiplying parcels of the larger scale by indicators of the…

  5. Estimating Latent Variable Interactions with the Unconstrained Approach: A Comparison of Methods to Form Product Indicators for Large, Unequal Numbers of Items

    Science.gov (United States)

    Jackman, M. Grace-Anne; Leite, Walter L.; Cochrane, David J.

    2011-01-01

    This Monte Carlo simulation study investigated methods of forming product indicators for the unconstrained approach for latent variable interaction estimation when the exogenous factors are measured by large and unequal numbers of indicators. Product indicators were created based on multiplying parcels of the larger scale by indicators of the…

  6. Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls

    Directory of Open Access Journals (Sweden)

    Marco Peluso

    2010-01-01

    Full Text Available Smoke constituents can induce DNA adducts that cause mutations and lead to lung cancer. We have analyzed DNA adducts and polymorphisms in two DNA repair genes, for example, XRCC1 Arg194Trp and Arg399Gln genes and XRCC3 Thr241Met gene, in 34 lung cancer cases in respect to 30 subjects with benign lung cancer disease and 40 healthy controls. When the study population was categorized in base to the number of risk alleles, adducts were significantly increased in individuals bearing 3-4 risk alleles (OR=4.1 95% C.I. 1.28–13.09, P=.009. A significant association with smoking was noticed in smokers for more than 40 years carrying 3-4 risk alleles (OR=36.38, 95% C.I. 1.17–1132.84, P=.040. A not statistically significant increment of lung cancer risk was observed in the same group (OR=4.54, 95% C.I. 0.33–62.93, P=.259. Our results suggest that the analysis of the number of risk alleles predicts the interindividual variation in DNA adducts of smokers and lung cancer cases.

  7. Bayesian item fit analysis for unidimensional item response theory models.

    Science.gov (United States)

    Sinharay, Sandip

    2006-11-01

    Assessing item fit for unidimensional item response theory models for dichotomous items has always been an issue of enormous interest, but there exists no unanimously agreed item fit diagnostic for these models, and hence there is room for further investigation of the area. This paper employs the posterior predictive model-checking method, a popular Bayesian model-checking tool, to examine item fit for the above-mentioned models. An item fit plot, comparing the observed and predicted proportion-correct scores of examinees with different raw scores, is suggested. This paper also suggests how to obtain posterior predictive p-values (which are natural Bayesian p-values) for the item fit statistics of Orlando and Thissen that summarize numerically the information in the above-mentioned item fit plots. A number of simulation studies and a real data application demonstrate the effectiveness of the suggested item fit diagnostics. The suggested techniques seem to have adequate power and reasonable Type I error rate, and psychometricians will find them promising.

  8. Dependability of technical items: Problems of standardization

    Science.gov (United States)

    Fedotova, G. A.; Voropai, N. I.; Kovalev, G. F.

    2016-12-01

    This paper is concerned with problems blown up in the development of a new version of the Interstate Standard GOST 27.002 "Industrial product dependability. Terms and definitions". This Standard covers a wide range of technical items and is used in numerous regulations, specifications, standard and technical documentation. A currently available State Standard GOST 27.002-89 was introduced in 1990. Its development involved a participation of scientists and experts from different technical areas, its draft was debated in different audiences and constantly refined, so it was a high quality document. However, after 25 years of its application it's become necessary to develop a new version of the Standard that would reflect the current understanding of industrial dependability, accounting for the changes taking place in Russia in the production, management and development of various technical systems and facilities. The development of a new version of the Standard makes it possible to generalize on a terminological level the knowledge and experience in the area of reliability of technical items, accumulated over a quarter of the century in different industries and reliability research schools, to account for domestic and foreign experience of standardization. Working on the new version of the Standard, we have faced a number of issues and problems on harmonization with the International Standard IEC 60500-192, caused first of all by different approaches to the use of terms and differences in the mentalities of experts from different countries. The paper focuses on the problems related to the chapter "Maintenance, restoration and repair", which caused difficulties for the developers to harmonize term definitions both with experts and the International Standard, which is mainly related to differences between the Russian concept and practice of maintenance and repair and foreign ones.

  9. Reward optimization of a repairable system

    Energy Technology Data Exchange (ETDEWEB)

    Castro, I.T. [Departamento de Matematicas, Facultad de Veterinaria, Universidad de Extremadura, Avenida de la Universidad, s/n. 10071 Caceres (Spain)]. E-mail: inmatorres@unex.es; Perez-Ocon, R. [Departamento de Estadistica e Investigacion Operativa, Facultad de Ciencias, Universidad de Granada, Avenida de Severo Ochoa, s/n. 18071 Granada (Spain)]. E-mail: rperezo@ugr.es

    2006-03-15

    This paper analyzes a system subject to repairable and non-repairable failures. Non-repairable failures lead to replacement of the system. Repairable failures, first lead to repair but they lead to replacement after a fixed number of repairs. Operating and repair times follow phase type distributions (PH-distributions) and the pattern of the operating times is modelled by a geometric process. In this context, the problem is to find the optimal number of repairs, which maximizes the long-run average reward per unit time. To this end, the optimal number is determined and it is obtained by efficient numerical procedures.

  10. Using automatic item generation to create multiple-choice test items.

    Science.gov (United States)

    Gierl, Mark J; Lai, Hollis; Turner, Simon R

    2012-08-01

    Many tests of medical knowledge, from the undergraduate level to the level of certification and licensure, contain multiple-choice items. Although these are efficient in measuring examinees' knowledge and skills across diverse content areas, multiple-choice items are time-consuming and expensive to create. Changes in student assessment brought about by new forms of computer-based testing have created the demand for large numbers of multiple-choice items. Our current approaches to item development cannot meet this demand. We present a methodology for developing multiple-choice items based on automatic item generation (AIG) concepts and procedures. We describe a three-stage approach to AIG and we illustrate this approach by generating multiple-choice items for a medical licensure test in the content area of surgery. To generate multiple-choice items, our method requires a three-stage process. Firstly, a cognitive model is created by content specialists. Secondly, item models are developed using the content from the cognitive model. Thirdly, items are generated from the item models using computer software. Using this methodology, we generated 1248 multiple-choice items from one item model. Automatic item generation is a process that involves using models to generate items using computer technology. With our method, content specialists identify and structure the content for the test items, and computer technology systematically combines the content to generate new test items. By combining these outcomes, items can be generated automatically. © Blackwell Publishing Ltd 2012.

  11. Dental Items of Significance, Number 43

    Science.gov (United States)

    1994-08-15

    UL certiication. DISADVANTAGES: - Tips are not interchangeable with Cavitron 30K-style tips. - Depends upon unit water for irrigation . - Nonsteilizable...The unit Is reconmmended by the mnanufacturer for use In prophylaxis, periodotal and endodontic treatmnent. Somrce: PERlOglene P.O. Box 9 Foat Calms...above ADVANTAGES: "+ Completely autoclavable handpiece and cable. "+ Abilty to delver sterile irrigating solution of choice. -,.- " Good operator comfort

  12. Dental Items of Significance, Number 42

    Science.gov (United States)

    1994-05-01

    of placement. Manufacturer:. Shofu Dental Corporation 4025 Bohannon Drive Menlo Park, CA 94025 (800) 827-4638 (415) 324-0085 (415) 323-3180 FAX Cost...tendency of oropharyngeal soft tissue to block the airway as the patient relaxes. Snoring occurs when relaxation of oropharyngeal muscles allows soft tissue...casts, block out excessive hard and soft tissue undercuts with baseplate wax and duplicate casts. (Optional) 3. Mount master casts using the wax

  13. Expected linking error resulting from item parameter drift among the common Items on Rasch calibrated tests.

    Science.gov (United States)

    Miller, G Edward; Gesn, Paul Randall; Rotou, Jourania

    2005-01-01

    In state assessment programs that employ Rasch-based common item linking procedures, the linking constant is usually estimated with only those common items not identified as exhibiting item difficulty parameter drift. Since state assessments typically contain a fixed number of items, an item classified as exhibiting parameter drift during the linking process remains on the exam as a scorable item even if it is removed from the common item set. Under the assumption that item parameter drift has occurred for one or more of the common items, the expected effect of including or excluding the "affected" item(s) in the estimation of the linking constant is derived in this article. If the item parameter drift is due solely to factors not associated with a change in examinee achievement, no linking error will (be expected to) occur given that the linking constant is estimated only with the items not identified as "affected"; linking error will (be expected to) occur if the linking constant is estimated with all common items. However, if the item parameter drift is due solely to change in examinee achievement, the opposite is true: no linking error will (be expected to) occur if the linking constant is estimated with all common items; linking error will (be expected to) occur if the linking constant is estimated only with the items not identified as "affected".

  14. Optimality in DNA repair.

    Science.gov (United States)

    Richard, Morgiane; Fryett, Matthew; Miller, Samantha; Booth, Ian; Grebogi, Celso; Moura, Alessandro

    2012-01-07

    DNA within cells is subject to damage from various sources. Organisms have evolved a number of mechanisms to repair DNA damage. The activity of repair enzymes carries its own risk, however, because the repair of two nearby lesions may lead to the breakup of DNA and result in cell death. We propose a mathematical theory of the damage and repair process in the important scenario where lesions are caused in bursts. We use this model to show that there is an optimum level of repair enzymes within cells which optimises the cell's response to damage. This optimal level is explained as the best trade-off between fast repair and a low probability of causing double-stranded breaks. We derive our results analytically and test them using stochastic simulations, and compare our predictions with current biological knowledge.

  15. A two-echelon(S-1,S)inventory model for repairable items based on markovian arrival process%基于马尔可夫到达过程的两级可修备件(S-1,S)库存优化模型

    Institute of Scientific and Technical Information of China (English)

    陈童; 黎放; 狄鹏

    2015-01-01

    本文以两级可修备件库存系统为研究对象,采用马尔可夫到达过程(MAP)描述备件需求规律,考虑有限维修设施的情况,假设故障件维修时间、备件运输时间以及采购时间均服从phase-type(PH)分布,建立了一种描述能力更强、解析计算性更好的(S-1,S)库存优化模型,并推导出系统缺货量分布函数;然后通过算例演示了模型的优化效果,验证了模型的正确性和适用性.%This paper investigates a two-echolon inventory system with(S-1,S)policy that consists of several same repairable items and single repair facility,and assumes that the item de-mand occur according to a markovian arrival process(MAP),the repair time,ship time and procurement time follow the general distribution which is represented by phase-type(PH)dis-tribution. Then a inventory optimization model with better description ability and analytical per-formance is given,and the probability distribution of backorder is obtained. Finally,a numeri-cal example was given to illustrate the effectiveness of the model.

  16. Índices baseados no número de clientes para localização de itens em armazéns Indexes based on the number of customers to locate items in warehouse

    Directory of Open Access Journals (Sweden)

    Marcele Elisa Fontana

    2013-01-01

    Full Text Available Para se obter eficiência nas operações de armazenagem, um fator importante é estabelecer a política ótima de atribuição da localização dos itens em armazéns. Para tanto, um dos índices mais difundidos e utilizados é o cuber-per-order (COI. No entanto, observa-se que há situações em que o uso do COI pode concentrar vantagens para uma minoria de clientes. Nesse sentido, este artigo propõe verificar as consequências da utilização de índices alternativos (COIC e CIC, baseados no número de clientes que demandam cada tipo de produto (item, sobre o desempenho de um armazém em relação à utilização do COI. Conclui-se que considerar o número de clientes na determinação da política ótima de atribuição de locais aos itens armazenados proporciona uma maior vantagem competitiva, uma vez que um número maior de clientes pode ser beneficiado. Isso representa uma oportunidade de elevar o nível de serviço oferecido pelo armazém aos clientes.An important factor to obtain efficiency of storage operations is to establish an optimal policy for storage location assignment. To this end, one of the indexes more circulated and used is the Cuber-per-Order (COI. However, it is observed that there are situations where the use of COI can concentrate advantages to a minority of clients. In this sense, this paper proposes to verify the effects on the performance of a warehouse when using alternative indexes (COIC and CIC, based on the number of clients that require each type of product (item, compared to the COI. It was possible to conclude that when the number of clients is considered to determine optimal policy for storage location assignment, the warehouse can acquire a competitive advantage, since the largest number of clients can be benefited. This represents an opportunity to raise the service level offered by the warehouse to its clients.

  17. Screening Test Items for Differential Item Functioning

    Science.gov (United States)

    Longford, Nicholas T.

    2014-01-01

    A method for medical screening is adapted to differential item functioning (DIF). Its essential elements are explicit declarations of the level of DIF that is acceptable and of the loss function that quantifies the consequences of the two kinds of inappropriate classification of an item. Instead of a single level and a single function, sets of…

  18. Grouping of Items in Mobile Web Questionnaires

    Science.gov (United States)

    Mavletova, Aigul; Couper, Mick P.

    2016-01-01

    There is some evidence that a scrolling design may reduce breakoffs in mobile web surveys compared to a paging design, but there is little empirical evidence to guide the choice of the optimal number of items per page. We investigate the effect of the number of items presented on a page on data quality in two types of questionnaires: with or…

  19. Tendon repair

    Science.gov (United States)

    Repair of tendon ... Tendon repair can be performed using: Local anesthesia (the immediate area of the surgery is pain-free) ... a cut on the skin over the injured tendon. The damaged or torn ends of the tendon ...

  20. NHRIC (National Health Related Items Code)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Health Related Items Code (NHRIC) is a system for identification and numbering of marketed device packages that is compatible with other numbering...

  1. NHRIC (National Health Related Items Code)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Health Related Items Code (NHRIC) is a system for identification and numbering of marketed device packages that is compatible with other numbering...

  2. Unidimensional IRT Item Parameter Estimates across Equivalent Test Forms with Confounding Specifications within Dimensions

    Science.gov (United States)

    Matlock, Ki Lynn; Turner, Ronna

    2016-01-01

    When constructing multiple test forms, the number of items and the total test difficulty are often equivalent. Not all test developers match the number of items and/or average item difficulty within subcontent areas. In this simulation study, six test forms were constructed having an equal number of items and average item difficulty overall.…

  3. A Process for Reviewing and Evaluating Generated Test Items

    Science.gov (United States)

    Gierl, Mark J.; Lai, Hollis

    2016-01-01

    Testing organization needs large numbers of high-quality items due to the proliferation of alternative test administration methods and modern test designs. But the current demand for items far exceeds the supply. Test items, as they are currently written, evoke a process that is both time-consuming and expensive because each item is written,…

  4. Construction and validation of an RNA trans-splicing molecule suitable to repair a large number of COL7A1 mutations.

    Science.gov (United States)

    Tockner, B; Kocher, T; Hainzl, S; Reichelt, J; Bauer, J W; Koller, U; Murauer, E M

    2016-11-01

    RNA trans-splicing has become a versatile tool in the gene therapy of monogenetic diseases. This technique is especially valuable for the correction of mutations in large genes such as COL7A1, which underlie the dystrophic subtype of the skin blistering disease epidermolysis bullosa. Over 800 mutations spanning the entire length of the COL7A1 gene have been associated with defects in type VII collagen, leading to excessive fragility of epithelial tissues, the hallmark of dystrophic epidermolysis bullosa (DEB). In the present study, we designed an RNA trans-splicing molecule (RTM) that is capable of repairing any given mutation within a 4200 nucleotide region spanning the 3' half of COL7A1. The selected RTM, RTM28, was able to induce accurate trans-splicing into endogenous COL7A1 pre-mRNA transcripts in a type VII collagen-deficient DEB patient-derived cell line. Correct trans-splicing was detected at the RNA level by semiquantitative RT-PCR and correction of full-length type VII collagen was confirmed at the protein level by immunofluorescence and western blot analyses. Our results demonstrate that RTM28, which covers >60% of all mutations reported in DEB and is thus the longest RTM described so far for the repair of COL7A1, represents a promising candidate for therapeutic applications.

  5. Bladder exstrophy repair

    Science.gov (United States)

    Bladder birth defect repair; Everted bladder repair; Exposed bladder repair; Repair of bladder exstrophy ... Bladder exstrophy repair involves two surgeries. The first surgery is to repair the bladder and the second one is to attach ...

  6. Writing better test items.

    Science.gov (United States)

    Aucoin, Julia W

    2005-01-01

    Professional development specialists have had little opportunity to learn how to write test items to meet the expectations of today's graduate nurse. Schools of nursing have moved away from knowledge-level test items and have had to develop more application and analysis items to prepare graduates for the National Council Licensure Examination (NCLEX). This same type of question can be used effectively to support a competence assessment system and document critical thinking skills.

  7. 28 Comparative Study of Open Mesh Repair and Desarda's No ...

    African Journals Online (AJOL)

    user

    2006-12-02

    Dec 2, 2006 ... East And Central African Journal of Surgery Volume 11 Number 2. ... new technique and the open mesh repair done in a district level general hospital set ... laparoscopic repairs or the patients given ..... Hernia repair (Open Vs.

  8. A Comparison of Anchor-Item Designs for the Concurrent Calibration of Large Banks of Likert-Type Items

    Science.gov (United States)

    Garcia-Perez, Miguel A.; Alcala-Quintana, Rocio; Garcia-Cueto, Eduardo

    2010-01-01

    Current interest in measuring quality of life is generating interest in the construction of computerized adaptive tests (CATs) with Likert-type items. Calibration of an item bank for use in CAT requires collecting responses to a large number of candidate items. However, the number is usually too large to administer to each subject in the…

  9. Repair-level analysis for Space Station Freedom

    Science.gov (United States)

    Chadwick, M.; Yaniec, J.

    1992-01-01

    To assign repair or discard-at-failure designations for orbital replacement units (ORUs) used on Space Station Freedom Electric Power System (SSFEPS), new algorithms and methods were required. Unique parameters, such as upmass costs, extravehicular activity costs and intravehicular activity (IVA) costs specific to Space Station Freedom's maintenance concept were incorporated into the Repair-Level Analysis (RLA). Additional outputs were also required of the SSFEPS RLA that were not required of previous RLAs. These outputs included recommendations for the number of launches that an ORU should be capable of attaining and an economic basis for condemnation rate. These unique parameters were not addressable using existing RLA models: therefore, a new approach was developed. In addition, it was found that preemptive analysis could be performed using spreadsheet-based Boolean expressions to represent the logical condition of the items under analysis.

  10. Hypospadias repair

    Science.gov (United States)

    ... the problem. If the repair is not done, problems may occur later on such as: Difficulty controlling and directing urine stream A curve in the penis during erection Decreased fertility Embarrassment about appearance of penis Surgery ...

  11. Evaluation of item candidates: the PROMIS qualitative item review.

    Science.gov (United States)

    DeWalt, Darren A; Rothrock, Nan; Yount, Susan; Stone, Arthur A

    2007-05-01

    One of the PROMIS (Patient-Reported Outcome Measurement Information System) network's primary goals is the development of a comprehensive item bank for patient-reported outcomes of chronic diseases. For its first set of item banks, PROMIS chose to focus on pain, fatigue, emotional distress, physical function, and social function. An essential step for the development of an item pool is the identification, evaluation, and revision of extant questionnaire items for the core item pool. In this work, we also describe the systematic process wherein items are classified for subsequent statistical processing by the PROMIS investigators. Six phases of item development are documented: identification of extant items, item classification and selection, item review and revision, focus group input on domain coverage, cognitive interviews with individual items, and final revision before field testing. Identification of items refers to the systematic search for existing items in currently available scales. Expert item review and revision was conducted by trained professionals who reviewed the wording of each item and revised as appropriate for conventions adopted by the PROMIS network. Focus groups were used to confirm domain definitions and to identify new areas of item development for future PROMIS item banks. Cognitive interviews were used to examine individual items. Items successfully screened through this process were sent to field testing and will be subjected to innovative scale construction procedures.

  12. Number of ruptured tendons and surgical delay as prognostic factors for the surgical repair of extensor tendon ruptures in the rheumatoid wrist.

    Science.gov (United States)

    Sakuma, Yu; Ochi, Kensuke; Iwamoto, Takuji; Saito, Asami; Yano, Koichiro; Naito, Yurino; Yoshida, Shinji; Ikari, Katsunori; Momohara, Shigeki

    2014-02-01

    Extensor tendon ruptures in the rheumatoid wrist are usually restored by extensor tendon reconstruction surgery. However, the factors significantly correlated with the outcomes of extensor tendon reconstruction have not been defined. We examined factors showing a statistically significant correlation with postoperative active motion after tendon reconstruction. Spontaneous extensor tendon ruptures of 66 wrists in patients (mean age, 52.6 yrs) with rheumatoid arthritis (RA) were evaluated. All patients underwent tendon reconstruction surgery with wrist arthroplasty or arthrodesis. Active ranges of motion of the affected fingers were evaluated at 12 weeks postsurgery. Statistical significance was determined using multiple and single regression analyses. Forty-six (69.6%) wrists had "good" results, while 13 (19.7%) and 7 (10.6%) wrists had "fair" and "poor" results, respectively. In multiple regression analysis, an increased number of ruptured tendons and the age at operation were independent variables significantly correlated with the postoperative active motion of reconstructed tendons (p = 0.009). Single regression analysis also showed a significant association between the number of ruptured tendons and surgical delay (p = 0.02). The number of ruptured extensor tendons was significantly correlated with the results of tendon reconstruction, and the number of ruptured tendons was significantly correlated with preoperative surgical delay. Our results indicate that, in patients presenting with possible finger extensor tendon rupture, rheumatologists should consult with hand surgeons promptly to preserve hand function.

  13. The Feasibility of Single-Item Measures for Organizational Justice

    Science.gov (United States)

    Jordan, Jeremy S.; Turner, Brian A.

    2008-01-01

    Researchers in a number of disciplines have examined the utility of single-item measures for both affective and cognitive constructs. While these authors have indicated that, under certain circumstances, the use of single-item measures is appropriate, there remains concern regarding the reliability and validity of single-item measures. This study…

  14. Classroom Test Writing: Effects of Item Format on Test Quality.

    Science.gov (United States)

    Torabi-Parizi, Rosa; Campbell, Noma Jo

    1982-01-01

    Investigates the effects of varying the placement of blanks and the number of options available in multiple-choice items on the reliability of fifth-grade students' scores. Results indicate that scores on three-choice item tests were not less reliable than scores on four-choice item tests. A similar finding was found regarding the placement of…

  15. Item Pool Design for an Operational Variable-Length Computerized Adaptive Test

    Science.gov (United States)

    He, Wei; Reckase, Mark D.

    2014-01-01

    For computerized adaptive tests (CATs) to work well, they must have an item pool with sufficient numbers of good quality items. Many researchers have pointed out that, in developing item pools for CATs, not only is the item pool size important but also the distribution of item parameters and practical considerations such as content distribution…

  16. Economic production quantity concerning learning and the reworking of imperfect items

    Directory of Open Access Journals (Sweden)

    Tsai Deng-Maw

    2012-01-01

    Full Text Available The classical economic production quantity (EPQ model assumes that items produced are of perfect quality and the production rate is constant. However, production quality depends on the condition of the process. Due to process deterioration or other factors, the production process may shift and produce imperfect quality items. These imperfect quality items sometimes can be reworked and repaired; hence, overall production-inventory costs can be reduced significantly. In addition, it can be found in practice that the time or cost required to repetitively produce a unit of a product decreases when the number of units produced by a worker or a group of workers increases. Under this circumstance, the unit production cost cannot be regarded as constant and, therefore, cannot be ignored when taking account of the total cost. This paper incorporates the effects of learning and the reworking of defective items on the EPQ model since they were not considered in existing models. An optimal operation policy that minimizes the expected total cost per unit time is derived. A numerical example is provided to illustrate the proposed model. In addition, sensitivity analysis is performed and discussed.

  17. Femoral hernia repair

    Science.gov (United States)

    Femorocele repair; Herniorrhaphy; Hernioplasty - femoral ... During surgery to repair the hernia, the bulging tissue is pushed back in. The weakened area is sewn closed or strengthened. This repair ...

  18. Undescended testicle repair

    Science.gov (United States)

    Orchidopexy; Inguinal orchidopexy; Orchiopexy; Repair of undescended testicle; Cryptorchidism repair ... first year of life without treatment. Undescended testicle repair surgery is recommended for patients whose testicles do ...

  19. 14 CFR 151.97 - Maintenance and repair.

    Science.gov (United States)

    2010-01-01

    ... or improper design; (4) Painting of buildings (inside and outside) and replacement of damaged items... and resealing surface of pavements. (b) Repair includes any work not included in paragraph (a) of...

  20. Item response theory - A first approach

    Science.gov (United States)

    Nunes, Sandra; Oliveira, Teresa; Oliveira, Amílcar

    2017-07-01

    The Item Response Theory (IRT) has become one of the most popular scoring frameworks for measurement data, frequently used in computerized adaptive testing, cognitively diagnostic assessment and test equating. According to Andrade et al. (2000), IRT can be defined as a set of mathematical models (Item Response Models - IRM) constructed to represent the probability of an individual giving the right answer to an item of a particular test. The number of Item Responsible Models available to measurement analysis has increased considerably in the last fifteen years due to increasing computer power and due to a demand for accuracy and more meaningful inferences grounded in complex data. The developments in modeling with Item Response Theory were related with developments in estimation theory, most remarkably Bayesian estimation with Markov chain Monte Carlo algorithms (Patz & Junker, 1999). The popularity of Item Response Theory has also implied numerous overviews in books and journals, and many connections between IRT and other statistical estimation procedures, such as factor analysis and structural equation modeling, have been made repeatedly (Van der Lindem & Hambleton, 1997). As stated before the Item Response Theory covers a variety of measurement models, ranging from basic one-dimensional models for dichotomously and polytomously scored items and their multidimensional analogues to models that incorporate information about cognitive sub-processes which influence the overall item response process. The aim of this work is to introduce the main concepts associated with one-dimensional models of Item Response Theory, to specify the logistic models with one, two and three parameters, to discuss some properties of these models and to present the main estimation procedures.

  1. The Role of Item Models in Automatic Item Generation

    Science.gov (United States)

    Gierl, Mark J.; Lai, Hollis

    2012-01-01

    Automatic item generation represents a relatively new but rapidly evolving research area where cognitive and psychometric theories are used to produce tests that include items generated using computer technology. Automatic item generation requires two steps. First, test development specialists create item models, which are comparable to templates…

  2. SHIPPING OF RADIOACTIVE ITEMS

    CERN Multimedia

    TIS/RP Group

    2001-01-01

    The TIS-RP group informs users that shipping of small radioactive items is normally guaranteed within 24 hours from the time the material is handed in at the TIS-RP service. This time is imposed by the necessary procedures (identification of the radionuclides, determination of dose rate and massive objects require a longer procedure and will therefore take longer.

  3. Intestinal obstruction repair

    Science.gov (United States)

    Repair of volvulus; Intestinal volvulus - repair; Bowel obstruction - repair ... Intestinal obstruction repair is done while you are under general anesthesia . This means you are asleep and DO NOT feel pain. ...

  4. Aortic aneurysm repair - endovascular

    Science.gov (United States)

    EVAR; Endovascular aneurysm repair - aorta; AAA repair - endovascular; Repair - aortic aneurysm - endovascular ... Endovascular aortic repair is done because your aneurysm is very large, growing quickly, or is leaking or bleeding. You may have ...

  5. Item Banking with Embedded Standards

    Science.gov (United States)

    MacCann, Robert G.; Stanley, Gordon

    2009-01-01

    An item banking method that does not use Item Response Theory (IRT) is described. This method provides a comparable grading system across schools that would be suitable for low-stakes testing. It uses the Angoff standard-setting method to obtain item ratings that are stored with each item. An example of such a grading system is given, showing how…

  6. Item Banking with Embedded Standards

    Science.gov (United States)

    MacCann, Robert G.; Stanley, Gordon

    2009-01-01

    An item banking method that does not use Item Response Theory (IRT) is described. This method provides a comparable grading system across schools that would be suitable for low-stakes testing. It uses the Angoff standard-setting method to obtain item ratings that are stored with each item. An example of such a grading system is given, showing how…

  7. Motorcycle Repair.

    Science.gov (United States)

    Hein, Jim; Bundy, Mike

    This motorcycle repair curriculum guide contains the following ten areas of study: brake systems, clutches, constant mesh transmissions, final drives, suspension, mechanical starting mechanisms, electrical systems, fuel systems, lubrication systems, and overhead camshafts. Each area consists of one or more units of instruction. Each instructional…

  8. A Retail Level Inventory Model for Naval Aviation Repairable Items.

    Science.gov (United States)

    1983-03-01

    given the appropriLate traffic irti y (or pipeline quantity) and protecti-on level a7ep- vd&’ Tables XII and XIII . ( Tabla XII was c-nmp,.ted by .si...Processes . ... 59 X. Revised TAT Limits . ............... 6a XI. RIPSIOP - ProFcsed Model Allowances ....... .5 XII . /1/1 Model Allowances, Infinite...nuaticn, boh1 nodl =-s use the same pipeline quantity compute d as P= X~ T, as explained in -the previous section. Table XII in7dicate=s t ha- heM/M/1

  9. Turbine repair process, repaired coating, and repaired turbine component

    Energy Technology Data Exchange (ETDEWEB)

    Das, Rupak; Delvaux, John McConnell; Garcia-Crespo, Andres Jose

    2015-11-03

    A turbine repair process, a repaired coating, and a repaired turbine component are disclosed. The turbine repair process includes providing a turbine component having a higher-pressure region and a lower-pressure region, introducing particles into the higher-pressure region, and at least partially repairing an opening between the higher-pressure region and the lower-pressure region with at least one of the particles to form a repaired turbine component. The repaired coating includes a silicon material, a ceramic matrix composite material, and a repaired region having the silicon material deposited on and surrounded by the ceramic matrix composite material. The repaired turbine component a ceramic matrix composite layer and a repaired region having silicon material deposited on and surrounded by the ceramic matrix composite material.

  10. 48 CFR 1371.103 - Additional item requirements (AIR)-growth work.

    Science.gov (United States)

    2010-10-01

    ... requirements (AIR)-growth work. 1371.103 Section 1371.103 Federal Acquisition Regulations System DEPARTMENT OF... Provisions and Clauses 1371.103 Additional item requirements (AIR)—growth work. Insert clause 1352.271-72, Additional Item Requirements (AIR)—Growth Work, in all solicitations and contracts for ship repair. ...

  11. Stochastic intensity for minimal repairs in heterogeneous populations

    OpenAIRE

    Cha, Ji Hwan; Finkelstein, Maxim

    2011-01-01

    In this note we revisit the discussion on minimal repair in heterogeneous populations in Finkelstein (2004). We consider the corresponding stochastic intensities (intensity processes) for items in heterogeneous populations given available information on their operational history, i.e. the failure (repair) times and the time since the last failure (repair). Based on the improved definitions, the setup of Finkelstein (2004) is modified and the main results are corrected in acc...

  12. SHIPPING OF RADIOACTIVE ITEMS

    CERN Multimedia

    TIS/RP Group

    2001-01-01

    The TIS-RP group informs users that shipping of small radioactive items is normally guaranteed within 24 hours from the time the material is handed in at the TIS-RP service. This time is imposed by the necessary procedures (identification of the radionuclides, determination of dose rate, preparation of the package and related paperwork). Large and massive objects require a longer procedure and will therefore take longer.

  13. Differential item functioning due to gender between depression and anxiety items among Chilean adolescents.

    Science.gov (United States)

    Bares, Cristina; Andrade, Fernando; Delva, Jorge; Grogan-Kaylor, Andrew; Kamata, Akihito

    2012-07-01

    Although much is known about the higher prevalence of anxiety and depressive disorders among adolescent females, less is known about the differential item endorsement due to gender in items of scales commonly used to measure anxiety and depression. We conducted a study to examine if adolescent males and females from Chile differed on how they endorsed the items of the Youth Self Report (YSR) anxious/depressed problem scale. We used data from a cross-sectional sample consisting of 925 participants (mean age = 14, SD 1.3, 49% females) of low to lower-middle socioeconomic status. A two-parameter logistic (2PL) IRT DIF model was fit. s revealed differential item functioning (DIF) by gender for six of the 13 items, with adolescent females being more likely to endorse a depression item while males were found more likely to endorse anxiety items. Findings suggest that items found in commonly used measures of anxiety and depression symptoms may not equally capture the true levels of these behavioural problems in adolescent males and females. Given the high levels of mental disorders in Chile and the surrounding countries, further attention should be focused on increasing the number of empirical studies examining potential gender differences in the assessment of mental health problems among Latin American populations to better aid our understanding of the phenomenology and determinants of these problems in the region.

  14. DNA repair mechanisms in C. elegans

    NARCIS (Netherlands)

    Brouwer, K.|info:eu-repo/dai/nl/336462557

    2009-01-01

    DNA is the carrier of genetic information. DNA is constantly damaged by, for example, UV light and X-rays. Cells can utilize a large number of proteins that can repair the damages, thereby avoiding changes in the DNA sequence. Damages that are not repaired result in an increase in the number of muta

  15. Faculty development on item writing substantially improves item quality.

    NARCIS (Netherlands)

    Naeem, N.; Vleuten, C.P.M. van der; Alfaris, E.A.

    2012-01-01

    The quality of items written for in-house examinations in medical schools remains a cause of concern. Several faculty development programs are aimed at improving faculty's item writing skills. The purpose of this study was to evaluate the effectiveness of a faculty development program in item develo

  16. IRT Item Parameter Scaling for Developing New Item Pools

    Science.gov (United States)

    Kang, Hyeon-Ah; Lu, Ying; Chang, Hua-Hua

    2017-01-01

    Increasing use of item pools in large-scale educational assessments calls for an appropriate scaling procedure to achieve a common metric among field-tested items. The present study examines scaling procedures for developing a new item pool under a spiraled block linking design. The three scaling procedures are considered: (a) concurrent…

  17. Other-initiated repair in Siwu

    Directory of Open Access Journals (Sweden)

    Dingemanse Mark

    2015-02-01

    Full Text Available This article describes the interactional patterns and linguistic structures associated with other-initiated repair in Siwu, a Kwa language spoken in eastern Ghana. Other-initiated repair is the set of techniques used by people to deal with problems in speaking, hearing and understanding. Formats for repair initiation in Siwu exploit language-specific resources like question words and noun class morphology. At the same time, the basic structure of the system bears a strong similarity to other-initiated repair in other languages. Practices described for Siwu thus are potentially of broader relevance to the study of other-initiated repair. This article documents how different prosodic realisations of repair initiators may index social actions and features of the speech event; how two distinct roles of repetition in repair initiators are kept apart by features of turn design; and what kinds of items can be treated as ‘dispensable’ in resayings. By charting how other-initiated repair uses local linguistic resources and yet is shaped by interactional needs that transcend particular languages, this study contributes to the growing field of pragmatic typology: the study of systems of language use and the principles that shape them.

  18. DNA repair in Chromobacterium violaceum.

    Science.gov (United States)

    Duarte, Fábio Teixeira; Carvalho, Fabíola Marques de; Bezerra e Silva, Uaska; Scortecci, Kátia Castanho; Blaha, Carlos Alfredo Galindo; Agnez-Lima, Lucymara Fassarella; Batistuzzo de Medeiros, Silvia Regina

    2004-03-31

    Chromobacterium violaceum is a Gram-negative beta-proteobacterium that inhabits a variety of ecosystems in tropical and subtropical regions, including the water and banks of the Negro River in the Brazilian Amazon. This bacterium has been the subject of extensive study over the last three decades, due to its biotechnological properties, including the characteristic violacein pigment, which has antimicrobial and anti-tumoral activities. C. violaceum promotes the solubilization of gold in a mercury-free process, and has been used in the synthesis of homopolyesters suitable for the production of biodegradable polymers. The complete genome sequence of this organism has been completed by the Brazilian National Genome Project Consortium. The aim of our group was to study the DNA repair genes in this organism, due to their importance in the maintenance of genomic integrity. We identified DNA repair genes involved in different pathways in C. violaceum through a similarity search against known sequences deposited in databases. The phylogenetic analyses were done using programs of the PHILYP package. This analysis revealed various metabolic pathways, including photoreactivation, base excision repair, nucleotide excision repair, mismatch repair, recombinational repair, and the SOS system. The similarity between the C. violaceum sequences and those of Neisserie miningitidis and Ralstonia solanacearum was greater than that between the C. violaceum and Escherichia coli sequences. The peculiarities found in the C. violaceum genome were the absence of LexA, some horizontal transfer events and a large number of repair genes involved with alkyl and oxidative DNA damage.

  19. REPAIR TECHNOLOGY IMPROVEMENT OF SPECIALIZED FREIGHT CARS

    Directory of Open Access Journals (Sweden)

    V. M. Bubnov

    2016-02-01

    Full Text Available Purpose. The volume of cargo transportation demands the introduction of a new generation of cars that would be able to provide all the needs of carriers. But this is impossible without the implementation of renovation repair facilities with the introduction of new technologies and modernization of the repair process. Repair of rolling stock is a key factor that must proceed with the establishment of new cars, as not all of the inventions may be repaired in car-repair depots, most of which are obsolete. The purpose is to analyze the possibility of increasing the efficiency of the repair process by introducing new repair technologies or improving the existing ones. It will improve not only the quality of the repair, but also its rate. Methodology. Works on improving the designs of freight cars are held by many design organizations in almost all industrialized countries. It makes repair organizations (depots and car-repair plants to upgrade the repair process. Achievements of-this goal is possible by improving the technology renovation and reorganization through the use of flexible flow technologies, which to date are the most effective in the repair of rolling stock. Findings. When performing the analysis it was determined that there are different designs of cars. More of cars are all-purpose and their repair does not cause difficulties for car-repair business. However, the number of specialized cars is also significant, and the technology of their repair should be improved. One of the reasons is that many models, such as tank wagons for the carriage of sulfur, are intended for the carriage of dangerous goods and their failure at the time of motion is not permitted. Originality. Firstly the authors have defined direction at improving technologies of repair specialized cars. Practical value. Actual improvement in the construction of cars is to improve the existing repair facilities. In addition, the repair technology using nowadays when repairing

  20. Scarf Repair of Composite Laminates

    Directory of Open Access Journals (Sweden)

    Xie Zonghong

    2016-01-01

    Full Text Available The use of composite materials, such as carbon-fiber reinforced plastic (CFRP composites, aero-structures has led to an increased need of advanced assembly joining and repair technologies. Adhesive bonded repairs as an alternative to recover full or part of initial strength were investigated. Tests were conducted with the objective of evaluating the effectiveness of techniques used for repairing damage fiber reinforced laminated composites. Failure loads and failure modes were generated and compared with the following parameters: scarf angles, roughness of grind tool and number of external plies. Results showed that scarf angle was the critical parameter and the largest tensile strength was observed with the smallest scarf angle. Besides, the use of external plies at the outer surface could not increase the repairs efficiency for large scarf angle. Preparing the repair surfaces by sanding them with a sander ranging from 60 to 100 grit number had significant effect on the failure load. These results allowed the proposal of design principles for repairing CFRP structures.

  1. DNA repair deficiency in neurodegeneration

    DEFF Research Database (Denmark)

    Jeppesen, Dennis Kjølhede; Bohr, Vilhelm A; Stevnsner, Tinna V.

    2011-01-01

    : homologous recombination and non-homologous end-joining. Ataxia telangiectasia and related disorders with defects in these pathways illustrate that such defects can lead to early childhood neurodegeneration. Aging is a risk factor for neurodegeneration and accumulation of oxidative mitochondrial DNA damage......Deficiency in repair of nuclear and mitochondrial DNA damage has been linked to several neurodegenerative disorders. Many recent experimental results indicate that the post-mitotic neurons are particularly prone to accumulation of unrepaired DNA lesions potentially leading to progressive...... neurodegeneration. Nucleotide excision repair is the cellular pathway responsible for removing helix-distorting DNA damage and deficiency in such repair is found in a number of diseases with neurodegenerative phenotypes, including Xeroderma Pigmentosum and Cockayne syndrome. The main pathway for repairing oxidative...

  2. Eye muscle repair - discharge

    Science.gov (United States)

    ... Lazy eye repair - discharge; Strabismus repair - discharge; Extraocular muscle surgery - discharge ... You or your child had eye muscle repair surgery to correct eye muscle ... term for crossed eyes is strabismus. Children most often ...

  3. Ventral hernia repair

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/007661.htm Ventral hernia repair To use the sharing features on this page, please enable JavaScript. Ventral hernia repair is surgery to repair a ventral hernia. ...

  4. Brain aneurysm repair

    Science.gov (United States)

    ... aneurysm repair; Dissecting aneurysm repair; Endovascular aneurysm repair - brain; Subarachnoid hemorrhage - aneurysm ... Your scalp, skull, and the coverings of the brain are opened. A metal clip is placed at ...

  5. Model Penjadwalan Batch Multi Item dengan Dependent Processing Time

    Directory of Open Access Journals (Sweden)

    Sukoyo Sukoyo

    2010-01-01

    Full Text Available This paper investigates a development of single machine batch scheduling for multi items with dependent processing time. The batch scheduling problem is to determine simultaneously number of batch (N, which item and its size allocated for each batch, and processing sequences of resulting batches. We use total actual flow time as the objective of schedule performance. The multi item batch scheduling problem could be formulated into a biner-integer nonlinear programming model because the number of batch should be in integer value, the allocation of items to resulting batch need binary values, and also there are some non-linearity on objective function and constraint due to the dependent processing time. By applying relaxation on the decision variable of number of batch (N as parameter, a heuristic procedure could be applied to find solution of the single machine batch scheduling problem for multi items.

  6. Bayesian Item Selection in Constrained Adaptive Testing Using Shadow Tests

    Science.gov (United States)

    Veldkamp, Bernard P.

    2010-01-01

    Application of Bayesian item selection criteria in computerized adaptive testing might result in improvement of bias and MSE of the ability estimates. The question remains how to apply Bayesian item selection criteria in the context of constrained adaptive testing, where large numbers of specifications have to be taken into account in the item…

  7. CrowdAidRepair: A Crowd-Aided Interactive Data Repairing Method

    KAUST Repository

    Zhou, Jian

    2016-03-25

    Data repairing aims at discovering and correcting erroneous data in databases. Traditional methods relying on predefined quality rules to detect the conflict between data may fail to choose the right way to fix the detected conflict. Recent efforts turn to use the power of crowd in data repairing, but the crowd power has its own drawbacks such as high human intervention cost and inevitable low efficiency. In this paper, we propose a crowd-aided interactive data repairing method which takes the advantages of both rule-based method and crowd-based method. Particularly, we investigate the interaction between crowd-based repairing and rule-based repairing, and show that by doing crowd-based repairing to a small portion of values, we can greatly improve the repairing quality of the rule-based repairing method. Although we prove that the optimal interaction scheme using the least number of values for crowd-based repairing to maximize the imputation recall is not feasible to be achieved, still, our proposed solution identifies an efficient scheme through investigating the inconsistencies and the dependencies between values in the repairing process. Our empirical study on three data collections demonstrates the high repairing quality of CrowdAidRepair, as well as the efficiency of the generated interaction scheme over baselines.

  8. Abdominal wall repair with human acellular dermal autograft

    Directory of Open Access Journals (Sweden)

    Roel E. Genders

    2011-12-01

    Full Text Available Repair of abdominal wall defects in the presence of contamination or infection is a significant problem. The loss of tissue warrants enforcement of the abdominal wall, preferably by autologous material. However, autologous repair often requires extensive surgery. This paper presents a review of available literature of placement of an acellular human dermis to repair an abdominal fascia defect, in contaminated as well as in non-contaminated surgical fields. It is illustrated with a case report that describes the successful reconstruction of an infected abdominal wall defect with a human acellular dermis allograft. A systematic literature review was undertaken with searches performed in the Pubmed and Cochrane databases for the period up till March 2009, using the search terms Alloderm [Substance Name], Hernia [Mesh] and the key words acellular dermis, acellular dermal matrix, human acellular dermal allograft and abdominal wall defect. To assess methodological quality, each article was subjected to a modification of the methodological index for non-randomized studies (MINORS according to Slim et al. Two items from the original index were not included because none of the studies selected had an unbiased assessment of the study end points and in none of the studies was a prospective calculation of the study size performed. Seventeen studies were included in the review. Data were extracted regarding study design, number of patients, surgical technique, followup period, contaminated or non-contaminated area of the fascia defect, mortality and morbidity (hemorrhage, seroma, wound dehiscence, infection of the operative procedure, the longterm results (removal of the graft, reherniation and bulging and level of evidencey. A total of 169 short-term complications and 151 longterm complications occurred after 643 surgical procedures reconstructing both contaminated and clean abdominal wall defects by implantation of an HADA. Human acellular dermal allograft

  9. Base excision repair in sugarcane

    Directory of Open Access Journals (Sweden)

    Agnez-Lima Lucymara F.

    2001-01-01

    Full Text Available DNA damage can be induced by a large number of physical and chemical agents from the environment as well as compounds produced by cellular metabolism. This type of damage can interfere with cellular processes such as replication and transcription, resulting in cell death and/or mutations. The low frequency of mutagenesis in cells is due to the presence of enzymatic pathways which repair damaged DNA. Several DNA repair genes (mainly from bacteria, yeasts and mammals have been cloned and their products characterized. The high conservation, especially in eukaryotes, of the majority of genes related to DNA repair argues for their importance in the maintenance of life on earth. In plants, our understanding of DNA repair pathways is still very poor, the first plant repair genes having only been cloned in 1997 and the mechanisms of their products have not yet been characterized. The objective of our data mining work was to identify genes related to the base excision repair (BER pathway, which are present in the database of the Sugarcane Expressed Sequence Tag (SUCEST Project. This search was performed by tblastn program. We identified sugarcane clusters homologous to the majority of BER proteins used in the analysis and a high degree of conservation was observed. The best results were obtained with BER proteins from Arabidopsis thaliana. For some sugarcane BER genes, the presence of more than one form of mRNA is possible, as shown by the occurrence of more than one homologous EST cluster.

  10. Modelling in Optimal Inspection and Repair

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Rackwitz, R.; Faber, M.H.;

    1991-01-01

    A model for reliability based optimal inspection and repair strategies is described. The total expected costs in the lifetime is minimized with the number of inspections, the inspection times and efforts, the repair crack size limit and a design parameter as optimization variables. The equivalenc...

  11. ONSTEP versus laparoscopy for inguinal hernia repair

    DEFF Research Database (Denmark)

    Andresen, Kristoffer; Burcharth, Jakob; Rosenberg, Jacob

    2015-01-01

    INTRODUCTION: The optimal repair of inguinal hernias remains controversial. It is recommended that an inguinal hernia be repaired using a mesh, either with a laparoscopic or an open approach. In Denmark, the laparoscopic approach is used in an increasing number of cases. The laparoscopic repair has...... clinical trial described in this protocol is to evaluate chronic pain after inguinal hernia repair using the ONSTEP method versus the laparoscopic approach. METHODS: This study is designed as a non-inferiority, two-arm, multicentre, randomised clinical trial, with a 1:1 allocation to ONSTEP or laparoscopic...

  12. ONSTEP versus laparoscopy for inguinal hernia repair

    DEFF Research Database (Denmark)

    Andresen, Kristoffer; Burcharth, Jakob; Rosenberg, Jacob

    2015-01-01

    INTRODUCTION: The optimal repair of inguinal hernias remains controversial. It is recommended that an inguinal hernia be repaired using a mesh, either with a laparoscopic or an open approach. In Denmark, the laparoscopic approach is used in an increasing number of cases. The laparoscopic repair has...... clinical trial described in this protocol is to evaluate chronic pain after inguinal hernia repair using the ONSTEP method versus the laparoscopic approach. METHODS: This study is designed as a non-inferiority, two-arm, multicentre, randomised clinical trial, with a 1:1 allocation to ONSTEP or laparoscopic...

  13. A Practical Procedure for the Construction and Reliability Analysis of Fixed Length Tests with Random Drawn Test Items

    NARCIS (Netherlands)

    Draaijer, S.; Klinkenberg, S.

    2015-01-01

    A procedure to construct valid and fair fixed-length tests with randomly drawn items from an item bank is described. The procedure provides guidelines for the set-up of a typical achievement test with regard to the number of items in the bank and the number of items for each position in a test. Furt

  14. Differential functioning of Bender Visual-Motor Gestalt Test items.

    Science.gov (United States)

    Sisto, Fermino Fernandes; Dos Santos, Acácia Aparecida Angeli; Noronha, Ana Paula Porto

    2010-02-01

    Differential Item Functioning (DIF) refers to items that do not function the same way for comparable members of different groups. The present study focuses on analyzing and classifying sex-related differential item functioning in the Bender Visual-Motor Gestalt Test. Subjects were 1,052 children attending public schools (513 boys, 539 girls, ages 6-10 years). The protocols were scored using the Bender Graduated Scoring System, which evaluates only the distortion criterion using the Rasch logistic response model. The scoring system fit the Rasch model, although two items were found to be biased by sex. When analyzing differential functioning of items for boys and girls separately, the number of differentially functioning items was equal.

  15. Combinatorial Reliability and Repair

    Science.gov (United States)

    1992-07-01

    Press, Oxford, 1987. [2] G. Gordon and L. Traldi, Generalized activities and the Tutte polynomial , Discrete Math. 85 (1990), 167-176. [3] A. B. Huseby, A...particular, Satyanarayana and Tindell introduced a notion of (K,j)-domination in their study of a K-terminal version of the chromatic polynomial [6], and it...G)) graphs. He also intends to look into the properties of the polynomial that gives the expected number of needed repairs of a K-terminal network

  16. GRE Verbal Analogy Items: Examinee Reasoning on Items.

    Science.gov (United States)

    Duran, Richard P.; And Others

    Information about how Graduate Record Examination (GRE) examinees solve verbal analogy problems was obtained in this study through protocol analysis. High- and low-ability subjects who had recently taken the GRE General Test were asked to "think aloud" as they worked through eight analogy items. These items varied factorially on the…

  17. Efficient Algorithms for Segmentation of Item-Set Time Series

    Science.gov (United States)

    Chundi, Parvathi; Rosenkrantz, Daniel J.

    We propose a special type of time series, which we call an item-set time series, to facilitate the temporal analysis of software version histories, email logs, stock market data, etc. In an item-set time series, each observed data value is a set of discrete items. We formalize the concept of an item-set time series and present efficient algorithms for segmenting a given item-set time series. Segmentation of a time series partitions the time series into a sequence of segments where each segment is constructed by combining consecutive time points of the time series. Each segment is associated with an item set that is computed from the item sets of the time points in that segment, using a function which we call a measure function. We then define a concept called the segment difference, which measures the difference between the item set of a segment and the item sets of the time points in that segment. The segment difference values are required to construct an optimal segmentation of the time series. We describe novel and efficient algorithms to compute segment difference values for each of the measure functions described in the paper. We outline a dynamic programming based scheme to construct an optimal segmentation of the given item-set time series. We use the item-set time series segmentation techniques to analyze the temporal content of three different data sets—Enron email, stock market data, and a synthetic data set. The experimental results show that an optimal segmentation of item-set time series data captures much more temporal content than a segmentation constructed based on the number of time points in each segment, without examining the item set data at the time points, and can be used to analyze different types of temporal data.

  18. A Mixed Effects Randomized Item Response Model

    Science.gov (United States)

    Fox, J.-P.; Wyrick, Cheryl

    2008-01-01

    The randomized response technique ensures that individual item responses, denoted as true item responses, are randomized before observing them and so-called randomized item responses are observed. A relationship is specified between randomized item response data and true item response data. True item response data are modeled with a (non)linear…

  19. DNA repair. [UV radiation

    Energy Technology Data Exchange (ETDEWEB)

    Setlow, R.

    1978-01-01

    Some topics discussed are as follows: difficulty in extrapolating data from E. coli to mammalian systems; mutations caused by UV-induced changes in DNA; mutants deficient in excision repair; other postreplication mechanisms; kinds of excision repair systems; detection of repair by biochemical or biophysical means; human mutants deficient in repair; mutagenic effects of UV on XP cells; and detection of UV-repair defects among XP individuals. (HLW)

  20. Item Veto: Dangerous Constitutional Tinkering.

    Science.gov (United States)

    Bellamy, Calvin

    1989-01-01

    In theory, the item veto would empower the President to remove wasteful and unnecessary projects from legislation. Yet, despite its history at the state level, the item veto is a loosely defined concept that may not work well at the federal level. Much more worrisome is the impact on the balance of power. (Author/CH)

  1. Conditional recall and the frequency effect in the serial recall task: an examination of item-to-item associativity.

    Science.gov (United States)

    Miller, Leonie M; Roodenrys, Steven

    2012-11-01

    The frequency effect in short-term serial recall is influenced by the composition of lists. In pure lists, a robust advantage in the recall of high-frequency (HF) words is observed, yet in alternating mixed lists, HF and low-frequency (LF) words are recalled equally well. It has been argued that the preexisting associations between all list items determine a single, global level of supportive activation that assists item recall. Preexisting associations between items are assumed to be a function of language co-occurrence; HF-HF associations are high, LF-LF associations are low, and mixed associations are intermediate in activation strength. This account, however, is based on results when alternating lists with equal numbers of HF and LF words were used. It is possible that directional association between adjacent list items is responsible for the recall patterns reported. In the present experiment, the recall of three forms of mixed lists-those with equal numbers of HF and LF items and pure lists-was examined to test the extent to which item-to-item associations are present in serial recall. Furthermore, conditional probabilities were used to examine more closely the evidence for a contribution, since correct-in-position scoring may mask recall that is dependent on the recall of prior items. The results suggest that an item-to-item effect is clearly present for early but not late list items, and they implicate an additional factor, perhaps the availability of resources at output, in the recall of late list items.

  2. Continuous Online Item Calibration: Parameter Recovery and Item Utilization.

    Science.gov (United States)

    Ren, Hao; van der Linden, Wim J; Diao, Qi

    2017-06-01

    Parameter recovery and item utilization were investigated for different designs for online test item calibration. The design was adaptive in a double sense: it assumed both adaptive testing of examinees from an operational pool of previously calibrated items and adaptive assignment of field-test items to the examinees. Four criteria of optimality for the assignment of the field-test items were used, each of them based on the information in the posterior distributions of the examinee's ability parameter during adaptive testing as well as the sequentially updated posterior distributions of the field-test item parameters. In addition, different stopping rules based on target values for the posterior standard deviations of the field-test parameters and the size of the calibration sample were used. The impact of each of the criteria and stopping rules on the statistical efficiency of the estimates of the field-test parameters and on the time spent by the items in the calibration procedure was investigated. Recommendations as to the practical use of the designs are given.

  3. Scaling: An Items Module

    Science.gov (United States)

    Tong, Ye; Kolen, Michael J.

    2010-01-01

    "Scaling" is the process of constructing a score scale that associates numbers or other ordered indicators with the performance of examinees. Scaling typically is conducted to aid users in interpreting test results. This module describes different types of raw scores and scale scores, illustrates how to incorporate various sources of…

  4. Quantum Partial Search of a Database with Several Target Items

    CERN Document Server

    Choi, B S; Choi, Byung-Soo; Korepin, Vladimir E

    2006-01-01

    We consider a database separated into blocks. Blocks containing target items are called target blocks. Blocks without target items are called non-target blocks. We consider a case, when each target block has the same number of target items. We present a fast quantum algorithm, which finds one of the target blocks. Our algorithm is based on Grover-Radhakrishnan algorithm of partial search. We minimize the number of queries to the oracle. We prove that for large size of the blocks the proposed algorithm shows universality and also shows how to use the algorithm for finite blocks.

  5. The modified Koyanagi hypospadias repair for the one-stage repair of proximal hypospadias

    Directory of Open Access Journals (Sweden)

    Venkata R Jayanthi

    2008-01-01

    Full Text Available Perineal and penoscrotal hypospadias were often managed by two-stage urethroplasty with variable results and significant number of these may need third surgery. Though modified Koyanagi one-stage repair has a learning curve, it has all the advantages of two-stage repair. The aim was to review the results of modified Koyonagi repair from the literature and our own centre experience.

  6. Assessing item fit for unidimensional item response theory models using residuals from estimated item response functions.

    Science.gov (United States)

    Haberman, Shelby J; Sinharay, Sandip; Chon, Kyong Hee

    2013-07-01

    Residual analysis (e.g. Hambleton & Swaminathan, Item response theory: principles and applications, Kluwer Academic, Boston, 1985; Hambleton, Swaminathan, & Rogers, Fundamentals of item response theory, Sage, Newbury Park, 1991) is a popular method to assess fit of item response theory (IRT) models. We suggest a form of residual analysis that may be applied to assess item fit for unidimensional IRT models. The residual analysis consists of a comparison of the maximum-likelihood estimate of the item characteristic curve with an alternative ratio estimate of the item characteristic curve. The large sample distribution of the residual is proved to be standardized normal when the IRT model fits the data. We compare the performance of our suggested residual to the standardized residual of Hambleton et al. (Fundamentals of item response theory, Sage, Newbury Park, 1991) in a detailed simulation study. We then calculate our suggested residuals using data from an operational test. The residuals appear to be useful in assessing the item fit for unidimensional IRT models.

  7. Complex networks repair strategies: Dynamic models

    Science.gov (United States)

    Fu, Chaoqi; Wang, Ying; Gao, Yangjun; Wang, Xiaoyang

    2017-09-01

    Network repair strategies are tactical methods that restore the efficiency of damaged networks; however, unreasonable repair strategies not only waste resources, they are also ineffective for network recovery. Most extant research on network repair focuses on static networks, but results and findings on static networks cannot be applied to evolutionary dynamic networks because, in dynamic models, complex network repair has completely different characteristics. For instance, repaired nodes face more severe challenges, and require strategic repair methods in order to have a significant effect. In this study, we propose the Shell Repair Strategy (SRS) to minimize the risk of secondary node failures due to the cascading effect. Our proposed method includes the identification of a set of vital nodes that have a significant impact on network repair and defense. Our identification of these vital nodes reduces the number of switching nodes that face the risk of secondary failures during the dynamic repair process. This is positively correlated with the size of the average degree and enhances network invulnerability.

  8. Item banking to improve, shorten and computerize self-reported fatigue: an illustration of steps to create a core item bank from the FACIT-Fatigue Scale.

    Science.gov (United States)

    Lai, Jin-shei; Cella, David; Chang, Chih-Hung; Bode, Rita K; Heinemann, Allen W

    2003-08-01

    Fatigue is a common symptom among cancer patients and the general population. Due to its subjective nature, fatigue has been difficult to effectively and efficiently assess. Modern computerized adaptive testing (CAT) can enable precise assessment of fatigue using a small number of items from a fatigue item bank. CAT enables brief assessment by selecting questions from an item bank that provide the maximum amount of information given a person's previous responses. This article illustrates steps to prepare such an item bank, using 13 items from the Functional Assessment of Chronic Illness Therapy Fatigue Subscale (FACIT-F) as the basis. Samples included 1022 cancer patients and 1010 people from the general population. An Item Response Theory (IRT)-based rating scale model, a polytomous extension of the Rasch dichotomous model was utilized. Nine items demonstrating acceptable psychometric properties were selected and positioned on the fatigue continuum. The fatigue levels measured by these nine items along with their response categories covered 66.8% of the general population and 82.6% of the cancer patients. Although the operational CAT algorithms to handle polytomously scored items are still in progress, we illustrated how CAT may work by using nine core items to measure level of fatigue. Using this illustration, a fatigue measure comparable to its full-length 13-item scale administration was obtained using four items. The resulting item bank can serve as a core to which will be added a psychometrically sound and operational item bank covering the entire fatigue continuum.

  9. Shock Wave-Stimulated Periosteum for Cartilage Repair

    Science.gov (United States)

    2015-03-01

    AD_________________ Award Number: W81XWH-10-1-0914 TITLE: Shock Wave-Stimulated Periosteum for Cartilage Repair PRINCIPAL INVESTIGATOR...30Sep2010 – 1Dec2014 4. TITLE AND SUBTITLE Shock Wave-Stimulated Periosteum for Cartilage Repair 5a. CONTRACT NUMBER W81XWH-10-1-0914 5b. GRANT NUMBER... shock wave (ESW)-stimulated periosteum improves cartilage repair when it is used as an autograft to fill a defect in the articular surface of goats. A

  10. Faculty development on item writing substantially improves item quality.

    Science.gov (United States)

    Naeem, Naghma; van der Vleuten, Cees; Alfaris, Eiad Abdelmohsen

    2012-08-01

    The quality of items written for in-house examinations in medical schools remains a cause of concern. Several faculty development programs are aimed at improving faculty's item writing skills. The purpose of this study was to evaluate the effectiveness of a faculty development program in item development. An objective method was developed and used to assess improvement in faculty's competence to develop high quality test items. This was a quasi experimental study with a pretest-midtest-posttest design. A convenience sample of 51 faculty members participated. Structured checklists were used to assess the quality of test items at each phase of the study. Group scores were analyzed using repeated measures analysis of variance. The results showed a significant increase in participants' mean scores on Multiple Choice Questions, Short Answer Questions and Objective Structured Clinical Examination checklists from pretest to posttest (p development are generally lacking in quality. It also provides evidence of the value of faculty development in improving the quality of items generated by faculty.

  11. Platelet-rich plasma for rotator cuff repair.

    Science.gov (United States)

    Barber, F Alan

    2013-12-01

    Rotator cuff tears are a common cause of shoulder pain and disability. Because they combine both traumatic and degenerative elements, the surgical repair can be challenging. Even after surgical intervention, tendon residual defects or "retears" often develop. Risk factors for tendon "retears" include patient age, number of tendons involved, tear size, and smoking. Platelet-rich plasma (PRP) is a supraphysiological concentration of platelets, which may be able to positively augment rotator cuff tendon healing. Not all PRPs are the same and those containing higher leukocyte levels may be detrimental to tendon healing. Thrombin activation triggers an immediate release of growth factors from the PRP and may actually inhibit some parts of the healing response. As yet, the clinical data does not conclusively prove a benefit from PRP, but discernment is required in evaluating the published results. As different PRPs may act differently and the results may be dose dependent requiring more PRP to achieve a beneficial threshold. How success is measured (clinical outcomes vs. intact cuff tendons) and how long the patients are followed are also critical items. Currently, the PRP fibrin matrix version holds the greatest promise for improving clinical success after rotator cuff tendon repair.

  12. Counting Frequencies from Zotero Items

    Directory of Open Access Journals (Sweden)

    Spencer Roberts

    2013-04-01

    Full Text Available In Counting Frequencies you learned how to count the frequency of specific words in a list using python. In this lesson, we will expand on that topic by showing you how to get information from Zotero HTML items, save the content from those items, and count the frequencies of words. It may be beneficial to look over the previous lesson before we begin.

  13. Adaptive testing for psychological assessment: how many items are enough to run an adaptive testing algorithm?

    Science.gov (United States)

    Wagner-Menghin, Michaela M; Masters, Geoff N

    2013-01-01

    Although the principles of adaptive testing were established in the psychometric literature many years ago (e.g., Weiss, 1977), and practice of adaptive testing is established in educational assessment, it not yet widespread in psychological assessment. One obstacle to adaptive psychological testing is a lack of clarity about the necessary number of items to run an adaptive algorithm. The study explores the relationship between item bank size, test length and measurement precision. Simulated adaptive test runs (allowing a maximum of 30 items per person) out of an item bank with 10 items per ability level (covering .5 logits, 150 items total) yield a standard error of measurement (SEM) of .47 (.39) after an average of 20 (29) items for 85-93% (64-82%) of the simulated rectangular sample. Expanding the bank to 20 items per level (300 items total) did not improve the algorithm's performance significantly. With a small item bank (5 items per ability level, 75 items total) it is possible to reach the same SEM as with a conventional test, but with fewer items or a better SEM with the same number of items.

  14. Multilevel Modeling of Item Position Effects

    Science.gov (United States)

    Albano, Anthony D.

    2013-01-01

    In many testing programs it is assumed that the context or position in which an item is administered does not have a differential effect on examinee responses to the item. Violations of this assumption may bias item response theory estimates of item and person parameters. This study examines the potentially biasing effects of item position. A…

  15. Pectus excavatum repair

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/002949.htm Pectus excavatum repair To use the sharing features on this page, please enable JavaScript. Pectus excavatum repair is surgery to correct pectus excavatum . This ...

  16. ONSTEP versus laparoscopy for inguinal hernia repair

    DEFF Research Database (Denmark)

    Andresen, Kristoffer; Burcharth, Jakob; Rosenberg, Jacob

    2015-01-01

    a learning curve of about 50-100 cases and decreases chronic pain, but slightly increases the risk of serious complications compared with open mesh repairs. Therefore, a simpler kind of operation is needed. The ONSTEP technique is a possible solution to this problem. The objective of the present randomised......INTRODUCTION: The optimal repair of inguinal hernias remains controversial. It is recommended that an inguinal hernia be repaired using a mesh, either with a laparoscopic or an open approach. In Denmark, the laparoscopic approach is used in an increasing number of cases. The laparoscopic repair has...... clinical trial described in this protocol is to evaluate chronic pain after inguinal hernia repair using the ONSTEP method versus the laparoscopic approach. METHODS: This study is designed as a non-inferiority, two-arm, multicentre, randomised clinical trial, with a 1:1 allocation to ONSTEP or laparoscopic...

  17. ONSTEP versus laparoscopy for inguinal hernia repair

    DEFF Research Database (Denmark)

    Andresen, Kristoffer; Burcharth, Jakob; Rosenberg, Jacob

    2015-01-01

    INTRODUCTION: The optimal repair of inguinal hernias remains controversial. It is recommended that an inguinal hernia be repaired using a mesh, either with a laparoscopic or an open approach. In Denmark, the laparoscopic approach is used in an increasing number of cases. The laparoscopic repair has...... a learning curve of about 50-100 cases and decreases chronic pain, but slightly increases the risk of serious complications compared with open mesh repairs. Therefore, a simpler kind of operation is needed. The ONSTEP technique is a possible solution to this problem. The objective of the present randomised...... clinical trial described in this protocol is to evaluate chronic pain after inguinal hernia repair using the ONSTEP method versus the laparoscopic approach. METHODS: This study is designed as a non-inferiority, two-arm, multicentre, randomised clinical trial, with a 1:1 allocation to ONSTEP or laparoscopic...

  18. Databases and Bioinformatics Tools for the Study of DNA Repair

    Directory of Open Access Journals (Sweden)

    Kaja Milanowska

    2011-01-01

    Full Text Available DNA is continuously exposed to many different damaging agents such as environmental chemicals, UV light, ionizing radiation, and reactive cellular metabolites. DNA lesions can result in different phenotypical consequences ranging from a number of diseases, including cancer, to cellular malfunction, cell death, or aging. To counteract the deleterious effects of DNA damage, cells have developed various repair systems, including biochemical pathways responsible for the removal of single-strand lesions such as base excision repair (BER and nucleotide excision repair (NER or specialized polymerases temporarily taking over lesion-arrested DNA polymerases during the S phase in translesion synthesis (TLS. There are also other mechanisms of DNA repair such as homologous recombination repair (HRR, nonhomologous end-joining repair (NHEJ, or DNA damage response system (DDR. This paper reviews bioinformatics resources specialized in disseminating information about DNA repair pathways, proteins involved in repair mechanisms, damaging agents, and DNA lesions.

  19. What factors make science test items especially difficult for students from minority groups?

    Directory of Open Access Journals (Sweden)

    Are Turmo

    2012-06-01

    Full Text Available Substantial gaps in science performance between majority and minority students are often found instandardized tests used in primary school. But at the item level, the gaps may vary significantly. Theaims of this study are: (1 to identify features of the test items in science (grade 5 and grade 8 students that can potentially explain group differences; and (2 to analyze what factors make test itemsespecially difficult for minority students. Explanatory variables such as reading load, item difficulty,item writing load, and use of the multiple-choice format are found to be major factors. The analysis reveals no empirical relationships between performance gap and either item subject domain, item test location, or the number of illustrations used in the item. Subtle issues regarding the design ofitems may influence the size of the performance gap at item level over and above the main explanatory variables. The gap can be reduced significantly by choosing “minority friendly” items.

  20. An Inventory Model with Price and Quality Dependent Demand Where Some Items Produced Are Defective

    Directory of Open Access Journals (Sweden)

    Tapan Kumar Datta

    2013-01-01

    Full Text Available This paper analyzes an inventory system for joint determination of product quality and selling price where a fraction of items produced are defective. It is assumed that only a fraction of defective items can be repaired/reworked. The demand rate depends upon both the quality and the selling price of the product. The production rate, unit price, and carrying cost depend upon the quality of the items produced. Quality index is used to determine the quality of the product. An algorithm is provided to solve the model with given values of model parameters. Sensitivity analysis has also been performed.

  1. Percutaneous mitral valve repair.

    Science.gov (United States)

    Gillinov, A Marc; Liddicoat, John R

    2006-01-01

    Surgical mitral valve repair is the procedure of choice to treat mitral regurgitation of all etiologies. Whereas annuloplasty is the cornerstone of mitral valve repair, a variety of other surgical techniques are utilized to correct dysfunction of the leaflets and subvalvular apparatus; in most cases, surgical repair entails application of multiple repair techniques in each patient. Preclinical studies and early human experience have demonstrated that some of these surgical repair techniques can be performed using percutaneous approaches. Specifically, there has been great progress in the development of novel technology to facilitate percutaneous annuloplasty and percutaneous edge-to-edge repair. The objectives of this report were to (1) discuss the surgical foundations for these percutaneous approaches; (2) review device design and experimental and clinical results of percutaneous valve repair; and (3) address future directions, including the key challenges of patient selection and clinical trial design.

  2. Australian Item Bank Program: Social Science Item Bank.

    Science.gov (United States)

    Australian Council for Educational Research, Hawthorn.

    After vigorous review, editing, and trial testing, this item bank was compiled to help secondary school teachers construct objective tests in the social sciences. Anthropology, economics, ethnic and cultural studies, geography, history, legal studies, politics, and sociology are among the topics represented. The bank consists of multiple choice…

  3. Quantum Partial Searching Algorithm of a Database with Several Target Items

    Institute of Scientific and Technical Information of China (English)

    ZHONG Pu-Cha; BAO Wan-Su; WEI Yun

    2009-01-01

    Choi and Korepin [Quantum Information Processing 6(2007)243] presented a quantum partial search algorithm of a database with several target items which can find a target block quickly when each target block contains the same number of target items. Actually, the number of target items in each target block is arbitrary. Aiming at this case, we give a condition to guarantee performance of the partial search algorithm to be performed and the number of queries to oracle of the algorithm to be minimized. In addition, by further numerical computing we come to the conclusion that the more uniform the distribution of target items, the smaller the number of queries.

  4. Repair welding process of friction stir welding groove defect

    Institute of Scientific and Technical Information of China (English)

    LIU Hui-jie; ZHANG Hui-jie

    2009-01-01

    The groove defect formed in the friction stir welding dramatically deteriorates weld appearances and mechanical properties of the joints owing to its larger size and penetration. Therefore, the friction stir repair welding was utilized to remove such a groove defect, and the focus was placed on the mechanical properties and microstructural characteristics of the repair joints so as to obtain an optimum repair welding process. The experimental results indicate that the groove defect can be removed by friction stir repair welding, and the offset repair welding process is superior to the symmetrical repair welding process. In the symmetrical repair welding process, a large number of fine cavity defects and an obvious aggregation of hard-brittle phase Al2Cu occur, accordingly the mechanical properties of the repair joint are weakened, and the fracture feature of repair joint is partially brittle and partially plastic. A good-quality repair joint can be obtained by the offset repair welding process, and the repair joint is fractured near the interface between the weld nugget zone and thermal-mechanically affected zone.

  5. Modelling sequentially scored item responses

    NARCIS (Netherlands)

    Akkermans, W.

    2000-01-01

    The sequential model can be used to describe the variable resulting from a sequential scoring process. In this paper two more item response models are investigated with respect to their suitability for sequential scoring: the partial credit model and the graded response model. The investigation is c

  6. Psychometric Consequences of Subpopulation Item Parameter Drift

    Science.gov (United States)

    Huggins-Manley, Anne Corinne

    2017-01-01

    This study defines subpopulation item parameter drift (SIPD) as a change in item parameters over time that is dependent on subpopulations of examinees, and hypothesizes that the presence of SIPD in anchor items is associated with bias and/or lack of invariance in three psychometric outcomes. Results show that SIPD in anchor items is associated…

  7. Psychometric Consequences of Subpopulation Item Parameter Drift

    Science.gov (United States)

    Huggins-Manley, Anne Corinne

    2017-01-01

    This study defines subpopulation item parameter drift (SIPD) as a change in item parameters over time that is dependent on subpopulations of examinees, and hypothesizes that the presence of SIPD in anchor items is associated with bias and/or lack of invariance in three psychometric outcomes. Results show that SIPD in anchor items is associated…

  8. Unidimensional Interpretations for Multidimensional Test Items

    Science.gov (United States)

    Kahraman, Nilufer

    2013-01-01

    This article considers potential problems that can arise in estimating a unidimensional item response theory (IRT) model when some test items are multidimensional (i.e., show a complex factorial structure). More specifically, this study examines (1) the consequences of model misfit on IRT item parameter estimates due to unintended minor item-level…

  9. Generalizability theory and item response theory

    NARCIS (Netherlands)

    Glas, Cornelis A.W.; Eggen, T.J.H.M.; Veldkamp, B.P.

    2012-01-01

    Item response theory is usually applied to items with a selected-response format, such as multiple choice items, whereas generalizability theory is usually applied to constructed-response tasks assessed by raters. However, in many situations, raters may use rating scales consisting of items with a

  10. Generalizability theory and item response theory

    NARCIS (Netherlands)

    Glas, C.A.W.; Eggen, T.J.H.M.; Veldkamp, B.P.

    2012-01-01

    Item response theory is usually applied to items with a selected-response format, such as multiple choice items, whereas generalizability theory is usually applied to constructed-response tasks assessed by raters. However, in many situations, raters may use rating scales consisting of items with a s

  11. 15 CFR 742.15 - Encryption items.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Encryption items. 742.15 Section 742... BASED CONTROLS § 742.15 Encryption items. Encryption items can be used to maintain the secrecy of... export and reexport of encryption items. As the President indicated in Executive Order 13026 and in his...

  12. Item-Writing Guidelines for Physics

    Science.gov (United States)

    Regan, Tom

    2015-01-01

    A teacher learning how to write test questions (test items) will almost certainly encounter item-writing guidelines--lists of item-writing do's and don'ts. Item-writing guidelines usually are presented as applicable across all assessment settings. Table I shows some guidelines that I believe to be generally applicable and two will be briefly…

  13. Unidimensional Interpretations for Multidimensional Test Items

    Science.gov (United States)

    Kahraman, Nilufer

    2013-01-01

    This article considers potential problems that can arise in estimating a unidimensional item response theory (IRT) model when some test items are multidimensional (i.e., show a complex factorial structure). More specifically, this study examines (1) the consequences of model misfit on IRT item parameter estimates due to unintended minor item-level…

  14. The Psychological Effect of Errors in Standardized Language Test Items on EFL Students' Responses to the Following Item

    Science.gov (United States)

    Khaksefidi, Saman

    2017-01-01

    This study investigates the psychological effect of a wrong question with wrong items on answering to the next question in a test of structure. Forty students selected through stratified random sampling are given 15 questions of a standardized test namely a TOEFL structure test in which questions number 7 and number 11 are wrong and their answers…

  15. The impact of item-writing flaws and item complexity on examination item difficulty and discrimination value.

    Science.gov (United States)

    Rush, Bonnie R; Rankin, David C; White, Brad J

    2016-09-29

    Failure to adhere to standard item-writing guidelines may render examination questions easier or more difficult than intended. Item complexity describes the cognitive skill level required to obtain a correct answer. Higher cognitive examination items promote critical thinking and are recommended to prepare students for clinical training. This study evaluated faculty-authored examinations to determine the impact of item-writing flaws and item complexity on the difficulty and discrimination value of examination items used to assess third year veterinary students. The impact of item-writing flaws and item complexity (cognitive level I-V) on examination item difficulty and discrimination value was evaluated on 1925 examination items prepared by clinical faculty for third year veterinary students. The mean (± SE) percent correct (83.3 % ± 17.5) was consistent with target values in professional education, and the mean discrimination index (0.18 ± 0.17) was slightly lower than recommended (0.20). More than one item-writing flaw was identified in 37.3 % of questions. The most common item-writing flaws were awkward stem structure, implausible distractors, longest response is correct, and responses are series of true-false statements. Higher cognitive skills (complexity level III-IV) were required to correctly answer 38.4 % of examination items. As item complexity increased, item difficulty and discrimination values increased. The probability of writing discriminating, difficult examination items decreased when implausible distractors and all of the above were used, and increased if the distractors were comprised of a series of true/false statements. Items with four distractors were not more difficult or discriminating than items with three distractors. Preparation of examination questions targeting higher cognitive levels will increase the likelihood of constructing discriminating items. Use of implausible distractors to complete a five-option multiple choice

  16. Shuttle Repair Tools Automate Vehicle Maintenance

    Science.gov (United States)

    2013-01-01

    Successfully building, flying, and maintaining the space shuttles was an immensely complex job that required a high level of detailed, precise engineering. After each shuttle landed, it entered a maintenance, repair, and overhaul (MRO) phase. Each system was thoroughly checked and tested, and worn or damaged parts replaced, before the shuttle was rolled out for its next mission. During the MRO period, workers needed to record exactly what needed replacing and why, as well as follow precise guidelines and procedures in making their repairs. That meant traceability, and with it lots of paperwork. In 2007, the number of reports generated during electrical system repairs was getting out of hand-placing among the top three systems in terms of paperwork volume. Repair specialists at Kennedy Space Center were unhappy spending so much time at a desk and so little time actually working on the shuttle. "Engineers weren't spending their time doing technical work," says Joseph Schuh, an electrical engineer at Kennedy. "Instead, they were busy with repetitive, time-consuming processes that, while important in their own right, provided a low return on time invested." The strain of such inefficiency was bad enough that slow electrical repairs jeopardized rollout on several occasions. Knowing there had to be a way to streamline operations, Kennedy asked Martin Belson, a project manager with 30 years experience as an aerospace contractor, to co-lead a team in developing software that would reduce the effort required to document shuttle repairs. The result was System Maintenance Automated Repair Tasks (SMART) software. SMART is a tool for aggregating and applying information on every aspect of repairs, from procedures and instructions to a vehicle s troubleshooting history. Drawing on that data, SMART largely automates the processes of generating repair instructions and post-repair paperwork. In the case of the space shuttle, this meant that SMART had 30 years worth of operations

  17. Repairs of composite structures

    Science.gov (United States)

    Roh, Hee Seok

    Repair on damaged composite panels was conducted. To better understand adhesively bonded repair, the study investigates the effect of design parameters on the joint strength. The design parameters include bondline length, thickness of adherend and type of adhesive. Adhesives considered in this study were tested to measure their tensile material properties. Three types of adhesively bonded joints, single strap, double strap, and single lap joint were considered under changing bondline lengths, thickness of adherend and type of adhesive. Based on lessons learned from bonded joints, a one-sided patch repair method for composite structures was conducted. The composite patch was bonded to the damaged panel by either film adhesive FM-73M or paste adhesive EA-9394 and the residual strengths of the repaired specimens were compared under varying patch sizes. A new repair method using attachments has been suggested to enhance the residual strength. Results obtained through experiments were analyzed using finite element analysis to provide a better repair design and explain the experimental results. It was observed that the residual strength of the repaired specimen was affected by patch length. Method for rapid repairs of damaged composite structures was investigated. The damage was represented by a circular hole in a composite laminated plate. Pre-cured composite patches were bonded with a quick-curing commercial adhesive near (rather than over) the hole. Tensile tests were conducted on specimens repaired with various patch geometries. The test results showed that, among the methods investigated, the best repair method restored over 90% of the original strength of an undamaged panel. The interfacial stresses in the adhesive zone for different patches were calculated in order to understand the efficiencies of the designs of these patch repairs. It was found that the composite patch that yielded the best strength had the lowest interfacial peel stress between the patch and

  18. Surgeon-Directed Cost Variation in Isolated Rotator Cuff Repair.

    Science.gov (United States)

    Terhune, E Bailey; Cannamela, Peter C; Johnson, Jared S; Saad, Charles D; Barnes, John; Silbernagel, Janette; Faciszewski, Thomas; Shea, Kevin G

    2016-12-01

    As value becomes a larger component of heath care decision making, cost data can be evaluated for regional and physician variation. Value is determined by outcome divided by cost, and reducing cost increases value for patients. "Third-party spend" items are individual selections by surgeons used to perform procedures. Cost data for third-party spend items provide surgeons and hospitals with important information regarding care value, potential cost-saving opportunities, and the total cost of ownership of specific clinical decisions. To perform a cost review of isolated rotator cuff repair within a regional 7-hospital system and to document procedure cost variation among operating surgeons. Economic and decision analysis; Level of evidence, 4. Current Procedural Terminology (CPT) codes were used to retrospectively identify subjects who received an isolated rotator cuff repair within a 7-hospital system. Cost data were collected for clinically sensitive third-party spend items and divided into 4 cost groups: (1) suture anchors, (2) suture-passing devices and needles, (3) sutures used for cuff repair, and (4) disposable tools or instruments. A total of 62 isolated rotator cuff repairs were performed by 17 surgeons over a 13-month period. The total cost per case for clinically sensitive third-party spend items (in 2015 US dollars) ranged from $293 to $3752 (mean, $1826). Four surgeons had a mean procedure cost that was higher than the data set mean procedure cost. The cost of an individual suture anchor ranged from $75 to $1775 (mean, $403). One disposable suture passer was used, which cost $140. The cost of passing needles ranged from $140 to $995 (mean, $468). The cost per repair suture (used to repair cuff tears) varied from $18 to $298 (mean, $61). The mean suture (used to close wounds) cost per case was $81 (range, $0-$454). A total of 316 tools or disposable instruments were used, costing $1 to $1573 per case (mean, $624). This study demonstrates significant cost

  19. Repairing Multiple Failures with Coordinated and Adaptive Regenerating Codes

    CERN Document Server

    Kermarrec, Anne-Marie; Scouarnec, Nicolas Le

    2011-01-01

    Erasure correcting codes are widely used to ensure data persistence in distributed storage systems. This paper addresses the repair of such codes in the presence of simultaneous failures. It is crucial to maintain the required redundancy over time to prevent permanent data losses. We go beyond existing work (i.e., regenerating codes by Dimakis et al.) and propose coordinated regenerating codes allowing devices to coordinate during simultaneous repairs thus reducing the costs further. We provide closed form expressions of the communication costs of our new codes depending on the number of live devices and the number of devices being repaired. We prove that deliberately delaying repairs does not bring additional gains in itself. This means that regenerating codes are optimal as long as each failure can be repaired before a second one occurs. Yet, when multiple failures are detected simultaneously, we prove that our coordinated regenerating codes are optimal and outperform uncoordinated repairs (with respect to ...

  20. Verbal fluency: Effect of time on item generation

    Directory of Open Access Journals (Sweden)

    Mayra Jacuviske Venegas

    Full Text Available Abstract The distribution of item generation/time in the performance of elderly on verbal fluency (VF remains unknown. Objective: To analyze the number of items, their distribution and impact of the first quartile on the final test result. Methods: 31 individuals performed the tests (average age=74 years; schooling=8.16 years. Results: The number of items produced in the first quartile differed from the other quartiles for both semantic and phonologic VF where 40% of items were produced in the first quartile. No effect of age was found and schooling influenced performance on the first and second quartiles of semantic VF and on the 1st, 2nd and 3rd quartiles of phonemic VF. Discussion: This study contributes with the finding that asymptotic levels are attained prior to the 30 seconds observed in other studies, being reached at the 15-second mark. Furthermore, schooling was found to be associated to the number of items produced in both the first and 2nd quartiles for semantic VF, and in 1st, 2nd and 3rd quartiles for phonemic fluency. Conclusion: The schooling effect was noted both in semantic and executive aspects of VF. The brief form of the VF test may represent a promising tool for clinical evaluation.

  1. Teoria da Resposta ao Item Teoria de la respuesta al item Item response theory

    Directory of Open Access Journals (Sweden)

    Eutalia Aparecida Candido de Araujo

    2009-12-01

    Full Text Available A preocupação com medidas de traços psicológicos é antiga, sendo que muitos estudos e propostas de métodos foram desenvolvidos no sentido de alcançar este objetivo. Entre os trabalhos propostos, destaca-se a Teoria da Resposta ao Item (TRI que, a princípio, veio completar limitações da Teoria Clássica de Medidas, empregada em larga escala até hoje na medida de traços psicológicos. O ponto principal da TRI é que ela leva em consideração o item particularmente, sem relevar os escores totais; portanto, as conclusões não dependem apenas do teste ou questionário, mas de cada item que o compõe. Este artigo propõe-se a apresentar esta Teoria que revolucionou a teoria de medidas.La preocupación con las medidas de los rasgos psicológicos es antigua y muchos estudios y propuestas de métodos fueron desarrollados para lograr este objetivo. Entre estas propuestas de trabajo se incluye la Teoría de la Respuesta al Ítem (TRI que, en principio, vino a completar las limitaciones de la Teoría Clásica de los Tests, ampliamente utilizada hasta hoy en la medida de los rasgos psicológicos. El punto principal de la TRI es que se tiene en cuenta el punto concreto, sin relevar las puntuaciones totales; por lo tanto, los resultados no sólo dependen de la prueba o cuestionario, sino que de cada ítem que lo compone. En este artículo se propone presentar la Teoría que revolucionó la teoría de medidas.The concern with measures of psychological traits is old and many studies and proposals of methods were developed to achieve this goal. Among these proposed methods highlights the Item Response Theory (IRT that, in principle, came to complete limitations of the Classical Test Theory, which is widely used until nowadays in the measurement of psychological traits. The main point of IRT is that it takes into account the item in particular, not relieving the total scores; therefore, the findings do not only depend on the test or questionnaire

  2. DESARDA’S NO MESH REPAIR VERSUS LICHTENSTEIN’S OPEN MESH REPAIR OF INGUINAL HERNIA: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Zaheer

    2015-09-01

    Full Text Available BACKGROUND : The tissue - based techniques are still acceptable for primary inguinal hernia repair according to the European Hernia Society guidelines. Desarda’s no mesh technique, introduced in 2001, is a hernia repair method using an undetached strip of external oblique Apo neurosis . This study compared outcomes after hernia repair with Desarda (D and mesh - based Lichtenstein (L techniques. METHODS : A total of 100 patients were randomly assigned to the D or L group (50 each. The primary outcomes measured were post - operative pain ( D ay1 and day 7, mean hospital stay (in days, return to basic activity (in days and recurrence. RESULTS : During the follow - up, no recurrences were observed in each group (p = 1.000. Average duration of the Desarda’s repair was 65.64 minutes, while the Lichtenstein repair lasted for 65.76 minutes. Mean VAS on 1 st post - operative day was significantly less in Desarda’s repair (2.86 than Lichenstein’s repair (3.50, (p=0.0004. Mean hospital stay was less in Desarda’s repair (2.58 days versus Lichtenstein’s repair (3.90 days p=0.0001. Return to basic physical activity was earlier in Desarda’s repair (7.04 days than Lichenstein’s repair (11.30 days, (p=<0.0001. However there was no recurrence in either group in 18 months follow up. CONCLUSIONS : The Desarda’s and Lichtenstein’s methods of primary inguinal hernia repair do not differ in the means of procedure complexity, surgery time and complication profile. However the return to basic physical activity was earlier in Desarda’s repair. Desarda’s no mesh repair is equally safe and more cost effective than Lichtenstein’s repair. The technique may potentially increase the number of tissue - based methods a vailable for treating inguinal hernias.

  3. Workshop on DNA repair.

    NARCIS (Netherlands)

    A.R. Lehmann (Alan); J.H.J. Hoeijmakers (Jan); A.A. van Zeeland (Albert); C.M.P. Backendorf (Claude); B.A. Bridges; A. Collins; R.P.D. Fuchs; G.P. Margison; R. Montesano; E. Moustacchi; A.T. Natarajan; M. Radman; A. Sarasin; E. Seeberg; C.A. Smith; M. Stefanini (Miria); L.H. Thompson; G.P. van der Schans; C.A. Weber (Christine); M.Z. Zdzienika

    1992-01-01

    textabstractA workshop on DNA repair with emphasis on eukaryotic systems was held, under the auspices of the EC Concerted Action on DNA Repair and Cancer, at Noordwijkerhout (The Netherlands) 14-19 April 1991. The local organization of the meeting was done under the auspices of the Medical Genetic C

  4. Laparoscopic lumbar hernia repair.

    Science.gov (United States)

    Madan, Atul K; Ternovits, Craig A; Speck, Karen E; Pritchard, F Elizabeth; Tichansky, David S

    2006-04-01

    Lumbar hernias are rare clinical entities that often pose a challenge for repair. Because of the surrounding anatomy, adequate surgical herniorraphy is often difficult. Minimally invasive surgery has become an option for these hernias. Herein, we describe two patients with lumbar hernias (one with a recurrent traumatic hernia and one with an incisional hernia). Both of these hernias were successfully repaired laparoscopically.

  5. Sharing the cost of redundant items

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Moulin, Hervé

    2014-01-01

    are network connectivity problems when an existing (possibly inefficient) network must be maintained. We axiomatize a family cost ratios based on simple liability indices, one for each agent and for each item, measuring the relative worth of this item across agents, and generating cost allocation rules......We ask how to share the cost of finitely many public goods (items) among users with different needs: some smaller subsets of items are enough to serve the needs of each user, yet the cost of all items must be covered, even if this entails inefficiently paying for redundant items. Typical examples...... additive in costs....

  6. Unfair items detection in educational measurement

    CERN Document Server

    Bakman, Yefim

    2012-01-01

    Measurement professionals cannot come to an agreement on the definition of the term 'item fairness'. In this paper a continuous measure of item unfairness is proposed. The more the unfairness measure deviates from zero, the less fair the item is. If the measure exceeds the cutoff value, the item is identified as definitely unfair. The new approach can identify unfair items that would not be identified with conventional procedures. The results are in accord with experts' judgments on the item qualities. Since no assumptions about scores distributions and/or correlations are assumed, the method is applicable to any educational test. Its performance is illustrated through application to scores of a real test.

  7. DNA repair protocols

    DEFF Research Database (Denmark)

    Bjergbæk, Lotte

    In its 3rd edition, this Methods in Molecular Biology(TM) book covers the eukaryotic response to genomic insult including advanced protocols and standard techniques in the field of DNA repair. Offers expert guidance for DNA repair, recombination, and replication. Current knowledge of the mechanisms...... that regulate DNA repair has grown significantly over the past years with technology advances such as RNA interference, advanced proteomics and microscopy as well as high throughput screens. The third edition of DNA Repair Protocols covers various aspects of the eukaryotic response to genomic insult including...... recent advanced protocols as well as standard techniques used in the field of DNA repair. Both mammalian and non-mammalian model organisms are covered in the book, and many of the techniques can be applied with only minor modifications to other systems than the one described. Written in the highly...

  8. INTERNAL REPAIR OF PIPELINES

    Energy Technology Data Exchange (ETDEWEB)

    Bill Bruce; Nancy Porter; George Ritter; Matt Boring; Mark Lozev; Ian Harris; Bill Mohr; Dennis Harwig; Robin Gordon; Chris Neary; Mike Sullivan

    2005-07-20

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without

  9. Differential item functioning analysis by applying multiple comparison procedures.

    Science.gov (United States)

    Eusebi, Paolo; Kreiner, Svend

    2015-01-01

    Analysis within a Rasch measurement framework aims at development of valid and objective test score. One requirement of both validity and objectivity is that items do not show evidence of differential item functioning (DIF). A number of procedures exist for the assessment of DIF including those based on analysis of contingency tables by Mantel-Haenszel tests and partial gamma coefficients. The aim of this paper is to illustrate Multiple Comparison Procedures (MCP) for analysis of DIF relative to a variable defining a very large number of groups, with an unclear ordering with respect to the DIF effect. We propose a single step procedure controlling the false discovery rate for DIF detection. The procedure applies for both dichotomous and polytomous items. In addition to providing evidence against a hypothesis of no DIF, the procedure also provides information on subset of groups that are homogeneous with respect to the DIF effect. A stepwise MCP procedure for this purpose is also introduced.

  10. Optimal Bayesian Adaptive Design for Test-Item Calibration.

    Science.gov (United States)

    van der Linden, Wim J; Ren, Hao

    2015-06-01

    An optimal adaptive design for test-item calibration based on Bayesian optimality criteria is presented. The design adapts the choice of field-test items to the examinees taking an operational adaptive test using both the information in the posterior distributions of their ability parameters and the current posterior distributions of the field-test parameters. Different criteria of optimality based on the two types of posterior distributions are possible. The design can be implemented using an MCMC scheme with alternating stages of sampling from the posterior distributions of the test takers' ability parameters and the parameters of the field-test items while reusing samples from earlier posterior distributions of the other parameters. Results from a simulation study demonstrated the feasibility of the proposed MCMC implementation for operational item calibration. A comparison of performances for different optimality criteria showed faster calibration of substantial numbers of items for the criterion of D-optimality relative to A-optimality, a special case of c-optimality, and random assignment of items to the test takers.

  11. INTERNAL REPAIR OF PIPELINES

    Energy Technology Data Exchange (ETDEWEB)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-12-31

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without

  12. A Bifactor Multidimensional Item Response Theory Model for Differential Item Functioning Analysis on Testlet-Based Items

    Science.gov (United States)

    Fukuhara, Hirotaka; Kamata, Akihito

    2011-01-01

    A differential item functioning (DIF) detection method for testlet-based data was proposed and evaluated in this study. The proposed DIF model is an extension of a bifactor multidimensional item response theory (MIRT) model for testlets. Unlike traditional item response theory (IRT) DIF models, the proposed model takes testlet effects into…

  13. Item calibration in incomplete testing designs

    NARCIS (Netherlands)

    Eggen, Theo J.H.M.; Verhelst, Norman D.

    2011-01-01

    This study discusses the justifiability of item parameter estimation in incomplete testing designs in item response theory. Marginal maximum likelihood (MML) as well as conditional maximum likelihood (CML) procedures are considered in three commonly used incomplete designs: random incomplete, multis

  14. INTERNAL REPAIR OF PIPELINES

    Energy Technology Data Exchange (ETDEWEB)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-08-17

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners

  15. Salvage hypospadias repairs

    Directory of Open Access Journals (Sweden)

    Sripathi V

    2008-01-01

    Full Text Available Aim: Review of our experience and to develop an algorithm for salvage procedures in the management of hypospadias cripples and treatment of urethral strictures following hypospadias repair. Methods: This is a retrospective review of hypospadias surgeries over a 41-month period. Out of a total 168 surgeries, 20 were salvage/re-operative repairs. In three children a Duplay repair was feasible, while in four others a variety of single-stage repairs could be done. The repair was staged in seven children - buccal mucosal grafts (BMGs in five, buccal mucosal tube in one, and skin graft in one. Five children with dense strictures were managed by dorsal BMG inlay grafting in one, vascularized tunical onlay grafting on the ventrum in one, and a free tunical patch in one. Three children were treated by internal urethrotomy and stenting for four weeks with a poor outcome. Results: The age of children ranged from 1.5-15 years (mean 4.5. Follow-up ranged from 3 months to 3.5 years. Excellent results were obtained in 10 children (50% with a well-surfaced erect penis and a slit-like meatus. Glans closure could not be achieved and meatus was coronal in three. Two children developed fistulae following a Duplay repair and following a staged BMG. Three repairs failed completely - a composite repair broke down, a BMG tube stenosed with a proximal leak, and a stricture recurred with loss of a ventral free tunical graft. Conclusions: In salvage procedures performed on hypospadias cripples, a staged repair with buccal mucosa as an inlay in the first stage followed by tubularization 4-6 months later provides good results. A simple algorithm to plan corrective surgery in failed hypospadias cases and obtain satisfactory results is devised.

  16. Processing Polarity Items: Contrastive Licensing Costs

    Science.gov (United States)

    Saddy, Douglas; Drenhaus, Heiner; Frisch, Stefan

    2004-01-01

    We describe an experiment that investigated the failure to license polarity items in German using event-related brain potentials (ERPs). The results reveal distinct processing reflexes associated with failure to license positive polarity items in comparison to failure to license negative polarity items. Failure to license both negative and…

  17. Towards an authoring system for item construction

    NARCIS (Netherlands)

    Rikers, Jos H.A.N.

    1988-01-01

    The process of writing test items is analyzed, and a blueprint is presented for an authoring system for test item writing to reduce invalidity and to structure the process of item writing. The developmental methodology is introduced, and the first steps in the process are reported. A historical revi

  18. Generalized Full-Information Item Bifactor Analysis

    Science.gov (United States)

    Cai, Li; Yang, Ji Seung; Hansen, Mark

    2011-01-01

    Full-information item bifactor analysis is an important statistical method in psychological and educational measurement. Current methods are limited to single-group analysis and inflexible in the types of item response models supported. We propose a flexible multiple-group item bifactor analysis framework that supports a variety of…

  19. Real and Artificial Differential Item Functioning

    Science.gov (United States)

    Andrich, David; Hagquist, Curt

    2012-01-01

    The literature in modern test theory on procedures for identifying items with differential item functioning (DIF) among two groups of persons includes the Mantel-Haenszel (MH) procedure. Generally, it is not recognized explicitly that if there is real DIF in some items which favor one group, then as an artifact of this procedure, artificial DIF…

  20. Item Response Methods for Educational Assessment.

    Science.gov (United States)

    Mislevy, Robert J.; Rieser, Mark R.

    Multiple matrix sampling (MMS) theory indicates how data may be gathered to most efficiently convey information about levels of attainment in a population, but standard analyses of these data require random sampling of items from a fixed pool of items. This assumption proscribes the retirement of flawed or obsolete items from the pool as well as…

  1. Matrix Sampling of Test Items. ERIC Digest.

    Science.gov (United States)

    Childs, Ruth A.; Jaciw, Andrew P.

    This Digest describes matrix sampling of test items as an approach to achieving broad coverage while minimizing testing time per student. Matrix sampling involves developing a complete set of items judged to cover the curriculum, then dividing the items into subsets and administering one subset to each student. Matrix sampling, by limiting the…

  2. The Multidimensionality of Verbal Analogy Items

    Science.gov (United States)

    Ullstadius, Eva; Carlstedt, Berit; Gustafsson, Jan-Eric

    2008-01-01

    The influence of general and verbal ability on each of 72 verbal analogy test items were investigated with new factor analytical techniques. The analogy items together with the Computerized Swedish Enlistment Battery (CAT-SEB) were given randomly to two samples of 18-year-old male conscripts (n = 8566 and n = 5289). Thirty-two of the 72 items had…

  3. Sales Models For Many Items Using Attribute Data

    NARCIS (Netherlands)

    J.E.M. van Nierop; D. Fok (Dennis); Ph.H.B.F. Franses (Philip Hans)

    2002-01-01

    textabstractSales models are mainly used to analyze markets with a fairly small number of items, obtained after aggregating to the brand level. In practice one may require analyses at a more disaggregate level. For example, brand managers may be interested in a comparison across product attributes.

  4. An Investigation of Item Fit Statistics for Mixed IRT Models

    Science.gov (United States)

    Chon, Kyong Hee

    2009-01-01

    The purpose of this study was to investigate procedures for assessing model fit of IRT models for mixed format data. In this study, various IRT model combinations were fitted to data containing both dichotomous and polytomous item responses, and the suitability of the chosen model mixtures was evaluated based on a number of model fit procedures.…

  5. Sales Models For Many Items Using Attribute Data

    NARCIS (Netherlands)

    J.E.M. van Nierop; D. Fok (Dennis); Ph.H.B.F. Franses (Philip Hans)

    2002-01-01

    textabstractSales models are mainly used to analyze markets with a fairly small number of items, obtained after aggregating to the brand level. In practice one may require analyses at a more disaggregate level. For example, brand managers may be interested in a comparison across product attributes.

  6. A Method for Severely Constrained Item Selection in Adaptive Testing.

    Science.gov (United States)

    Stocking, Martha L.; Swanson, Len

    1993-01-01

    A method is presented for incorporating a large number of constraints on adaptive item selection in the construction of computerized adaptive tests. The method, which emulates practices of expert test specialists, is illustrated for verbal and quantitative measures. Its foundation is application of a weighted deviations model and algorithm. (SLD)

  7. Optimal item pool design for computerized adaptive tests with polytomous items using GPCM

    Directory of Open Access Journals (Sweden)

    Xuechun Zhou

    2014-09-01

    Full Text Available Computerized adaptive testing (CAT is a testing procedure with advantages in improving measurement precision and increasing test efficiency. An item pool with optimal characteristics is the foundation for a CAT program to achieve those desirable psychometric features. This study proposed a method to design an optimal item pool for tests with polytomous items using the generalized partial credit model (G-PCM. It extended a method for approximating optimality with polytomous items being described succinctly for the purpose of pool design. Optimal item pools were generated using CAT simulations with and without practical constraints of content balancing and item exposure control. The performances of the item pools were evaluated against an operational item pool. The results indicated that the item pools designed with stratification based on discrimination parameters performed well with an efficient use of the less discriminative items within the target accuracy levels. The implications for developing item pools are also discussed.

  8. Emergency Power For Critical Items

    Science.gov (United States)

    Young, William R.

    2009-07-01

    Natural disasters, such as hurricanes, floods, tornados, and tsunami, are becoming a greater problem as climate change impacts our environment. Disasters, whether natural or man made, destroy lives, homes, businesses and the natural environment. Such disasters can happen with little or no warning, leaving hundreds or even thousands of people without medical services, potable water, sanitation, communications and electrical services for up to several weeks. In our modern world, the need for electricity has become a necessity. Modern building codes and new disaster resistant building practices are reducing the damage to homes and businesses. Emergency gasoline and diesel generators are becoming common place for power outages. Generators need fuel, which may not be available after a disaster, but Photovoltaic (solar-electric) systems supply electricity without petroleum fuel as they are powered by the sun. Photovoltaic (PV) systems can provide electrical power for a home or business. PV systems can operate as utility interactive or stand-alone with battery backup. Determining your critical load items and sizing the photovoltaic system for those critical items, guarantees their operation in a disaster.

  9. Intact Transition Epitope Mapping (ITEM)

    Science.gov (United States)

    Yefremova, Yelena; Opuni, Kwabena F. M.; Danquah, Bright D.; Thiesen, Hans-Juergen; Glocker, Michael O.

    2017-08-01

    Intact transition epitope mapping (ITEM) enables rapid and accurate determination of protein antigen-derived epitopes by either epitope extraction or epitope excision. Upon formation of the antigen peptide-containing immune complex in solution, the entire mixture is electrosprayed to translate all constituents as protonated ions into the gas phase. There, ions from antibody-peptide complexes are separated from unbound peptide ions according to their masses, charges, and shapes either by ion mobility drift or by quadrupole ion filtering. Subsequently, immune complexes are dissociated by collision induced fragmentation and the ion signals of the "complex-released peptides," which in effect are the epitope peptides, are recorded in the time-of-flight analyzer of the mass spectrometer. Mixing of an antibody solution with a solution in which antigens or antigen-derived peptides are dissolved is, together with antigen proteolysis, the only required in-solution handling step. Simplicity of sample handling and speed of analysis together with very low sample consumption makes ITEM faster and easier to perform than other experimental epitope mapping methods.

  10. Choreography of oxidative damage repair in mammalian genomes.

    Science.gov (United States)

    Mitra, Sankar; Izumi, Tadahide; Boldogh, Istvan; Bhakat, Kishor K; Hill, Jeff W; Hazra, Tapas K

    2002-07-01

    The lesions induced by reactive oxygen species in both nuclear and mitochondrial genomes include altered bases, abasic (AP) sites, and single-strand breaks, all repaired primarily via the base excision repair (BER) pathway. Although the basic BER process (consisting of five sequential steps) could be reconstituted in vitro with only four enzymes, it is now evident that repair of oxidative damage, at least in mammalian cell nuclei, is more complex, and involves a number of additional proteins, including transcription- and replication-associated factors. These proteins may be required in sequential repair steps in concert with other cellular changes, starting with nuclear targeting of the early repair enzymes in response to oxidative stress, facilitation of lesion recognition, and access by chromatin unfolding via histone acetylation, and formation of metastable complexes of repair enzymes and other accessory proteins. Distinct, specific subclasses of protein complexes may be formed for repair of oxidative lesions in the nucleus in transcribed vs. nontranscribed sequences in chromatin, in quiescent vs. cycling cells, and in nascent vs. parental DNA strands in replicating cells. Characterizing the proteins for each repair subpathway, their signaling-dependent modifications and interactions in the nuclear as well as mitochondrial repair complexes, will be a major focus of future research in oxidative damage repair.

  11. Approximation Preserving Reductions among Item Pricing Problems

    Science.gov (United States)

    Hamane, Ryoso; Itoh, Toshiya; Tomita, Kouhei

    When a store sells items to customers, the store wishes to determine the prices of the items to maximize its profit. Intuitively, if the store sells the items with low (resp. high) prices, the customers buy more (resp. less) items, which provides less profit to the store. So it would be hard for the store to decide the prices of items. Assume that the store has a set V of n items and there is a set E of m customers who wish to buy those items, and also assume that each item i ∈ V has the production cost di and each customer ej ∈ E has the valuation vj on the bundle ej ⊆ V of items. When the store sells an item i ∈ V at the price ri, the profit for the item i is pi = ri - di. The goal of the store is to decide the price of each item to maximize its total profit. We refer to this maximization problem as the item pricing problem. In most of the previous works, the item pricing problem was considered under the assumption that pi ≥ 0 for each i ∈ V, however, Balcan, et al. [In Proc. of WINE, LNCS 4858, 2007] introduced the notion of “loss-leader, ” and showed that the seller can get more total profit in the case that pi < 0 is allowed than in the case that pi < 0 is not allowed. In this paper, we derive approximation preserving reductions among several item pricing problems and show that all of them have algorithms with good approximation ratio.

  12. A new serial number marking system applicable to firearms identification.

    Science.gov (United States)

    Polk, D E; Giessen, B C

    1975-07-01

    A new system for physically recording serial numbers on individual items is proposed. Each serial number is converted to a unique array of points, and this array is recorded on the item by drilling a set of holes having the arrangement of the array into the item. Laser drilling can be used to produce holes of small diameter for the array. The identifying marks extend into the item and cannot be readily removed as surface stampings. In some cases the serial number can be marked in a critical area, so that its removal would destroy the usefulness of the item. This system is particularly suitable for the marking of firearms.

  13. Using Automated Processes to Generate Test Items And Their Associated Solutions and Rationales to Support Formative Feedback

    Directory of Open Access Journals (Sweden)

    Mark Gierl

    2015-08-01

    Full Text Available Automatic item generation is the process of using item models to produce assessment tasks using computer technology. An item model is similar to a template that highlights the elements in the task that must be manipulated to produce new items. The purpose of our study is to describe an innovative method for generating large numbers of diverse and heterogeneous items along with their solutions and associated rationales to support formative feedback. We demonstrate the method by generating items in two diverse content areas, mathematics and nonverbal reasoning

  14. Acceptable nationwide outcome after paediatric inguinal hernia repair

    DEFF Research Database (Denmark)

    Bisgaard, Thue; Kehlet, H; Oehlenschlager, J;

    2014-01-01

    PURPOSE: The primary objective was to describe 30-day outcomes after primary inguinal paediatric hernia repair. METHODS: Prospectively collected data from the National Patient Registry covering a 2-year study period 1 January 2005 to 31 December 2006 were collected. Unexpected outcomes were defined...... was not associated with the inguinal hernia repair. The usual technique was a simple sutured plasty (96.5 %). Emergency repair was performed in 54 patients (2.2 %) mainly in children between 0 and 2 years (79.6 %). During the 1 year follow-up, reoperation for recurrent inguinal hernia was performed in 8 children...... after elective repair (recurrence rate 0.3 %). Paediatric repairs were for most parts performed in surgical public hospitals, and most departments performed less than 10 inguinal hernia repairs within the 2 years study period. CONCLUSION: These nationwide results are acceptable with low numbers...

  15. Reducing cost of repair materials for automatic melt injection furnace. Jido chutoro no hoshuyo zairyohi no sakugen

    Energy Technology Data Exchange (ETDEWEB)

    Yasushita, Y.; Nouchi, T.; Nagano, T.; Tamaru, I.; Hasei, S.; Hamano, K.; Suimizu, T.; Okamoto, M. (Nippon Kokan Pipe Fitting Co. Ltd., Osaka (Japan))

    1992-08-25

    This paper summarizes discussion intended of reducing material cost implemented at a casting department which produces materials for pipe joints covering 600 to 650 models. Targets were placed on reducing the current material cost by 30%, the currently used repair jigs by 30%, as well as reducing repair works and manpower. First, a Pareto chart was sought on monetary amount of materials used, to identify items requiring sizable material costs. Items identified include reduction of amount of heat insulating materials used for sensor protection, slug removal cost, and refractories. With respect to the heat insulating materials, the cut sizes were discussed, and as a result , difference among individuals was eliminated molten face levels were prevented from being positioned too high , and the number of replacement due to damages was reduces. The rate of heat insulating material reduction was 39%. As regards the slug removal cost, the cost was reduced by reusing waste materials, the inductor channels were changed, and the method of operating the automatic molten metal pouring furnace was improved. With regard to the refractories, the shell width of troughs was covered with steel plates to reduce the use amount, the replacement manpower was reduced, and the use of expensive refractories was minimized. 10 figs., 5 tabs.

  16. Progress of peripheral nerve repair

    Institute of Scientific and Technical Information of China (English)

    陈峥嵘

    2002-01-01

    Study on repair of peripheral nerve injury has been proceeding over a long period of time. With the use of microsurgery technique since 1960s,the quality of nerve repair has been greatly improved. In the past 40 years, with the continuous increase of surgical repair methods, more progress has been made on the basic research of peripheral nerve repair.

  17. Achilles tendon repair

    Science.gov (United States)

    Achilles tendon rupture-surgery; Percutaneous Achilles tendon rupture repair ... To fix your torn Achilles tendon, the surgeon will: Make a cut down the back of your heel Make several small cuts rather than one large cut ...

  18. Diaphragmatic hernia repair - slideshow

    Science.gov (United States)

    ... presentations/100014.htm Diaphragmatic hernia repair - series—Normal anatomy To use the sharing ... Overview The chest cavity includes the heart and lungs. The abdominal cavity includes the liver, the stomach, ...

  19. Eye muscle repair - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100062.htm Eye muscle repair - series—Normal anatomy To use the sharing ... the eyeball to the eye socket. The external muscles of the eye are found behind the conjunctiva. ...

  20. Tracheoesophageal fistula repair - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100103.htm Tracheoesophageal fistula repair - series—Normal anatomy To use the sharing ... Editorial team. Related MedlinePlus Health Topics Esophagus Disorders Fistulas Tracheal Disorders A.D.A.M., Inc. is ...

  1. Inguinal hernia repair - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100027.htm Inguinal hernia repair - series—Normal anatomy To use the sharing ... to slide 4 out of 4 Overview A hernia occurs when part of an organ protrudes through ...

  2. INTERNAL REPAIR OF PIPELINES

    Energy Technology Data Exchange (ETDEWEB)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; Nancy Porter; Mike Sullivan; Chris Neary

    2004-04-12

    The two broad categories of deposited weld metal repair and fiber-reinforced composite liner repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repair and for fiber-reinforced composite liner repair. Evaluation trials have been conducted using a modified fiber-reinforced composite liner provided by RolaTube and pipe sections without liners. All pipe section specimens failed in areas of simulated damage. Pipe sections containing fiber-reinforced composite liners failed at pressures marginally greater than the pipe sections without liners. The next step is to evaluate a liner material with a modulus of elasticity approximately 95% of the modulus of elasticity for steel. Preliminary welding parameters were developed for deposited weld metal repair in preparation of the receipt of Pacific Gas & Electric's internal pipeline welding repair system (that was designed specifically for 559 mm (22 in.) diameter pipe) and the receipt of 559 mm (22 in.) pipe sections from Panhandle Eastern. The next steps are to transfer welding parameters to the PG&E system and to pressure test repaired pipe sections to failure. A survey of pipeline operators was conducted to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. Completed surveys contained the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created

  3. Pectus excavatum repair - slideshow

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/presentations/100035.htm Pectus excavatum repair - series—Normal anatomy To use the sharing ... Go to slide 4 out of 4 Overview Pectus excavatum is a deformity of the front of the ...

  4. Hiatal hernia repair - slideshow

    Science.gov (United States)

    ... presentations/100028.htm Hiatal hernia repair - series—Normal anatomy To use the sharing features on ... Overview The esophagus runs through the diaphragm to the stomach. It functions to carry food from the mouth ...

  5. Repairing ceramic insulating tiles

    Science.gov (United States)

    Dunn, B. R.; Laymance, E. L.

    1980-01-01

    Fused-silica tiles containing large voids or gauges are repaired without adhesives by plug insertion method. Tiles are useful in conduits for high-temperature gases, in furnaces, and in other applications involving heat insulation.

  6. Rotator cuff repair - slideshow

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/presentations/100229.htm Rotator cuff repair - series—Normal anatomy To use the sharing ... to slide 4 out of 4 Overview The rotator cuff is a group of muscles and tendons that ...

  7. Cleft lip repair - slideshow

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/presentations/100010.htm Cleft lip repair - series—Normal anatomy To use the sharing ... abnormal opening in the middle of the upper lip. A cleft palate is an opening in the roof of ...

  8. Grey Repairable System Analysis

    Institute of Scientific and Technical Information of China (English)

    Renkuan Guo; Charles Ernie Love

    2006-01-01

    In this paper, we systematically discuss the basic concepts of grey theory, particularly the grey differential equation and its mathematical foundation, which is essentially unknown in the reliability engineering community. Accordingly,we propose a small-sample based approach to estimate repair improvement effects by partitioning system stopping times into intrinsic functioning times and repair improvement times. An industrial data set is used for illustrative purposes in a stepwise manner.

  9. Losing Items in the Psychogeriatric Nursing Home

    Directory of Open Access Journals (Sweden)

    J. van Hoof PhD

    2016-09-01

    Full Text Available Introduction: Losing items is a time-consuming occurrence in nursing homes that is ill described. An explorative study was conducted to investigate which items got lost by nursing home residents, and how this affects the residents and family caregivers. Method: Semi-structured interviews and card sorting tasks were conducted with 12 residents with early-stage dementia and 12 family caregivers. Thematic analysis was applied to the outcomes of the sessions. Results: The participants stated that numerous personal items and assistive devices get lost in the nursing home environment, which had various emotional, practical, and financial implications. Significant amounts of time are spent on trying to find items, varying from 1 hr up to a couple of weeks. Numerous potential solutions were identified by the interviewees. Discussion: Losing items often goes together with limitations to the participation of residents. Many family caregivers are reluctant to replace lost items, as these items may get lost again.

  10. Instructional Topics in Educational Measurement (ITEMS) Module: Using Automated Processes to Generate Test Items

    Science.gov (United States)

    Gierl, Mark J.; Lai, Hollis

    2013-01-01

    Changes to the design and development of our educational assessments are resulting in the unprecedented demand for a large and continuous supply of content-specific test items. One way to address this growing demand is with automatic item generation (AIG). AIG is the process of using item models to generate test items with the aid of computer…

  11. New technologies for item monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, J.A. [EG & G Energy Measurements, Albuquerque, NM (United States); Waddoups, I.G. [Sandia National Labs., Albuquerque, NM (United States)

    1993-12-01

    This report responds to the Department of Energy`s request that Sandia National Laboratories compare existing technologies against several advanced technologies as they apply to DOE needs to monitor the movement of material, weapons, or personnel for safety and security programs. The authors describe several material control systems, discuss their technologies, suggest possible applications, discuss assets and limitations, and project costs for each system. The following systems are described: WATCH system (Wireless Alarm Transmission of Container Handling); Tag system (an electrostatic proximity sensor); PANTRAK system (Personnel And Material Tracking); VRIS (Vault Remote Inventory System); VSIS (Vault Safety and Inventory System); AIMS (Authenticated Item Monitoring System); EIVS (Experimental Inventory Verification System); Metrox system (canister monitoring system); TCATS (Target Cueing And Tracking System); LGVSS (Light Grid Vault Surveillance System); CSS (Container Safeguards System); SAMMS (Security Alarm and Material Monitoring System); FOIDS (Fiber Optic Intelligence & Detection System); GRADS (Graded Radiation Detection System); and PINPAL (Physical Inventory Pallet).

  12. Number line representations of fractions

    OpenAIRE

    Behr, Merlyn J.; Bright, George W.; Wachsmuth, Ipke; Wagner, Sigrid

    1982-01-01

    The study explored students' interpretations of representations of fractions on number lines and the effect of instruction on those interpretations. Subjects were five fourth-graders, and instruction was a four-day unit on the use of number lines. A 16-item, multiple-choice pre- and posttest was used along with videotaped interviews. Performance improved except when students had to associate a reduced fraction symbol with an equivalent, unreduced fraction representation on a number line. The ...

  13. PENGEMBANGAN TES BERPIKIR KRITIS DENGAN PENDEKATAN ITEM RESPONSE THEORY

    Directory of Open Access Journals (Sweden)

    Fajrianthi Fajrianthi

    2016-06-01

    Assumption, Deduction, Interpretation dan Evaluation of arguments. 1453 respondents from Surabaya, Gresik, Tuban, Bojonegoro and Rembang were used for trailing the test. The dichotomous data were analized using the Item Response Theory with two parameter logistic model using statistical program Mplus ver. 6.11. Several assumptions were tested prior the IRT analysis; the test of unidimensionality, local independency and Item Characteristic Curve (ICC. Amongst 68 items only 15 items had good discrimination parameter. Difficulty item level ranged from – 4.95 to 2.448. The study was limited in producing high number of qualified items due to its failure in finding subject matter experts in critical thinking area and inadequate choice in scoring method. Keywords: test development, critical thinking, Item response theory

  14. The Onstep Method for Inguinal Hernia Repair

    DEFF Research Database (Denmark)

    Rosenberg, Jacob; Andresen, Kristoffer

    2016-01-01

    Inguinal hernia repair is one of the most common surgical procedures and several different surgical techniques are available. The Onstep method is a new promising technique. The technique is simple with a number of straightforward steps. This paper provides a full description of the technique...

  15. Reversed item bias: an integrative model.

    Science.gov (United States)

    Weijters, Bert; Baumgartner, Hans; Schillewaert, Niels

    2013-09-01

    In the recent methodological literature, various models have been proposed to account for the phenomenon that reversed items (defined as items for which respondents' scores have to be recoded in order to make the direction of keying consistent across all items) tend to lead to problematic responses. In this article we propose an integrative conceptualization of three important sources of reversed item method bias (acquiescence, careless responding, and confirmation bias) and specify a multisample confirmatory factor analysis model with 2 method factors to empirically test the hypothesized mechanisms, using explicit measures of acquiescence and carelessness and experimentally manipulated versions of a questionnaire that varies 3 item arrangements and the keying direction of the first item measuring the focal construct. We explain the mechanisms, review prior attempts to model reversed item bias, present our new model, and apply it to responses to a 4-item self-esteem scale (N = 306) and the 6-item Revised Life Orientation Test (N = 595). Based on the literature review and the empirical results, we formulate recommendations on how to use reversed items in questionnaires.

  16. Exploring differential item functioning in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC

    Directory of Open Access Journals (Sweden)

    Pollard Beth

    2012-12-01

    Full Text Available Abstract Background The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC is a widely used patient reported outcome in osteoarthritis. An important, but frequently overlooked, aspect of validating health outcome measures is to establish if items exhibit differential item functioning (DIF. That is, if respondents have the same underlying level of an attribute, does the item give the same score in different subgroups or is it biased towards one subgroup or another. The aim of the study was to explore DIF in the Likert format WOMAC for the first time in a UK osteoarthritis population with respect to demographic, social, clinical and psychological factors. Methods The sample comprised a community sample of 763 people with osteoarthritis who participated in the Somerset and Avon Survey of Health. The WOMAC was explored for DIF by gender, age, social deprivation, social class, employment status, distress, body mass index and clinical factors. Ordinal regression models were used to identify DIF items. Results After adjusting for age, two items were identified for the physical functioning subscale as having DIF with age identified as the DIF factor for 2 items, gender for 1 item and body mass index for 1 item. For the WOMAC pain subscale, for people with hip osteoarthritis one item was identified with age-related DIF. The impact of the DIF items rarely had a significant effect on the conclusions of group comparisons. Conclusions Overall, the WOMAC performed well with only a small number of DIF items identified. However, as DIF items were identified in for the WOMAC physical functioning subscale it would be advisable to analyse data taking into account the possible impact of the DIF items when weight, gender or especially age effects, are the focus of interest in UK-based osteoarthritis studies. Similarly for the WOMAC pain subscale in people with hip osteoarthritis it would be worthwhile to analyse data taking into account the

  17. An Analysis of Serial Number Tracking Automatic Identification Technology as Used in Naval Aviation Programs

    Science.gov (United States)

    Csorba, Robert

    2002-09-01

    The Government Accounting Office found that the Navy, between 1996 and 1998, lost 3 billion in materiel in-transit. This thesis explores the benefits and cost of automatic identification and serial number tracking technologies under consideration by the Naval Supply Systems Command and the Naval Air Systems Command. Detailed cost-savings estimates are made for each aircraft type in the Navy inventory. Project and item managers of repairable components using Serial Number Tracking were surveyed as to the value of this system. It concludes that two thirds of the in-transit losses can be avoided with implementation of effective information technology-based logistics and maintenance tracking systems. Recommendations are made for specific steps and components of such an implementation. Suggestions are made for further research.

  18. 2D motion analysis of rabbits after Achilles tendon rupture repair and histological analysis of extracted tendons: can the number of animals be reduced by operating both hind legs simultaneously?

    Science.gov (United States)

    Buschmann, Johanna; Müller, Angela; Nicholls, Flora; Achermann, Rita; Bürgisser, Gabriella Meier; Baumgartner, Walter; Calcagni, Maurizio; Giovanoli, Pietro

    2013-10-01

    Considering the 3Rs principle in animal experiments, there is a demand to perform research experiments with the fewest number of animals possible while warranting the welfare of the animals. Orthopaedic experimental studies involving operations on the hind legs of rabbits are either performed on one hind leg with the second hind leg serving as control or on both hind legs simultaneously (control: rabbits with no operations at all). The Achilles tendon of rabbits was transected and sutured, and the two-dimensional motion pattern of animals having only one leg operated was compared to rabbits having both hind legs operated (control: non-treated animals). Step length, maximum ankle angle, minimum ankle angle and the resulting range of motion of both hind legs were determined weekly over a time span from 3 weeks to 12 weeks post-operation. The results were fitted by a linear mixed effects model including time dependency. Moreover, all tendon specimen were analysed histologically. Tenocyte and tenoblast density, tenocyte and tenoblast nuclei width, inflammation level and collagen fibre alignment were determined. Statistically significant differences in the motion pattern were found when one-leg treated and two-leg treated animals were compared. However, the absolute differences were on average less than 20%. Histologically, 1-leg treated animals had tendon tissue with higher cell density, but lower inflammation and less ondulated collagen fibres compared to 2-leg treated animals; the nuclei width was the same for both groups. With regard to welfare, all animals were fine during the experiments. While comparative studies should be performed with one-leg treated animals due to interaction effects, for proof-of-principle studies, operating two legs per animal may be justified as the welfare of the animals is warranted. This is a great benefit in the sense of the 3Rs because up to 50% of animals can be spared. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Element Salience as a Predictor of Item Difficulty for Raven's Progressive Matrices

    Science.gov (United States)

    Meo, Maria; Roberts, Maxwell J.; Marucci, Francesco S.

    2007-01-01

    Raven's Progressive Matrices is a frequently used intelligence test, and it has been suggested that the major determinant of difficulty for each item is its numbers of elements and rules, and its rule complexity. The current study investigated another potential source of difficulty--element salience--items are harder where their elements are…

  20. Some Properties of the Pearson Correlation Matrix of Guttman-Scalable Items.

    Science.gov (United States)

    Zwick, Rebecca

    Although perfectly scalable items rarely occur in practice, Guttman's concept of a scale has proved to be valuable to the development of measurement theory. If the score distribution is uniform and there is an equal number of items at each difficulty level, both the elements and the eigenvalues of the Pearson correlation matrix of dichotomous…

  1. Ontology Alignment Repair through Modularization and Confidence-Based Heuristics.

    Directory of Open Access Journals (Sweden)

    Emanuel Santos

    Full Text Available Ontology Matching aims at identifying a set of semantic correspondences, called an alignment, between related ontologies. In recent years, there has been a growing interest in efficient and effective matching methods for large ontologies. However, alignments produced for large ontologies are often logically incoherent. It was only recently that the use of repair techniques to improve the coherence of ontology alignments began to be explored. This paper presents a novel modularization technique for ontology alignment repair which extracts fragments of the input ontologies that only contain the necessary classes and relations to resolve all detectable incoherences. The paper presents also an alignment repair algorithm that uses a global repair strategy to minimize both the degree of incoherence and the number of mappings removed from the alignment, while overcoming the scalability problem by employing the proposed modularization technique. Our evaluation shows that our modularization technique produces significantly small fragments of the ontologies and that our repair algorithm produces more complete alignments than other current alignment repair systems, while obtaining an equivalent degree of incoherence. Additionally, we also present a variant of our repair algorithm that makes use of the confidence values of the mappings to improve alignment repair. Our repair algorithm was implemented as part of AgreementMakerLight, a free and open-source ontology matching system.

  2. Examining item difficulty and response time on perceptual ability test items.

    Science.gov (United States)

    Yang, Chien-Lin; O'Neill, Thomas R; Kramer, Gene A

    2002-01-01

    This study examined item calibration stability in relation to response time and the levels of item difficulty between different response time groups on a sample of 389 examinees responding to six different subtest items of the Perceptual Ability Test (PAT). The results indicated that no Differential Item Functioning (DIF) was found and a significant correlation coefficient of item difficulty was formed between slow and fast responders. Three distinct levels of difficulty emerged among the six subtests across groups. Slow responders spent significantly more time than fast responders on the four most difficult subtests. A positive significant relationship was found between item difficulty and response time across groups on the overall perceptual ability test items. Overall, this study found that: 1) the same underlying construct is being measured across groups, 2) the PAT scores were equally useful across groups, 3) different sources of item difficulty may exist among the six subtests, and 4) more difficult test items may require more time to answer.

  3. From concepts to lexical items.

    Science.gov (United States)

    Bierwisch, M; Schreuder, R

    1992-03-01

    In this paper we address the question how in language production conceptual structures are mapped onto lexical items. First we describe the lexical system in a fairly abstract way. Such a system consists of, among other things, a fixed set of basic lexical entries characterized by four groups of information: phonetic form, grammatical features, argument structure, and semantic form. A crucial assumption of the paper is that the meaning in a lexical entry has a complex internal structure composed of more primitive elements (decomposition). Some aspects of argument structure and semantic form and their interaction are discussed with respect to the issue of synonymy. We propose two different mappings involved in lexical access. One maps conceptual structures to semantic forms, and the other maps semantic forms to conceptual structures. Both mappings are context dependent and are many-to-many mappings. We present an elaboration of Levelt's (1989) model in which these processes interact with the grammatical encoder and the mental lexicon. Then we address the consequences of decomposition for processing models, especially the nature of the input of lexical access and the time course. Processing models that use the activation metaphor may have difficulties accounting for certain phenomena where a certain lemma triggers not one, but two or more word forms that have to be produced with other word forms in between.

  4. Repair Optimal Erasure Codes through Hadamard Designs

    CERN Document Server

    Papailiopoulos, Dimitris S; Cadambe, Viveck R

    2011-01-01

    In distributed storage systems that employ erasure coding, the issue of minimizing the total {\\it communication} required to exactly rebuild a storage node after a failure arises. This repair bandwidth depends on the structure of the storage code and the repair strategies used to restore the lost data. Designing high-rate maximum-distance separable (MDS) codes that achieve the optimum repair communication has been a well-known open problem. In this work, we use Hadamard matrices to construct the first explicit 2-parity MDS storage code with optimal repair properties for all single node failures, including the parities. Our construction relies on a novel method of achieving perfect interference alignment over finite fields with a finite file size, or number of extensions. We generalize this construction to design $m$-parity MDS codes that achieve the optimum repair communication for single systematic node failures and show that there is an interesting connection between our $m$-parity codes and the systematic-...

  5. Detecting and Correcting Speech Repairs

    CERN Document Server

    Heeman, P A; Heeman, Peter; Allen, James

    1994-01-01

    Interactive spoken dialog provides many new challenges for spoken language systems. One of the most critical is the prevalence of speech repairs. This paper presents an algorithm that detects and corrects speech repairs based on finding the repair pattern. The repair pattern is built by finding word matches and word replacements, and identifying fragments and editing terms. Rather than using a set of prebuilt templates, we build the pattern on the fly. In a fair test, our method, when combined with a statistical model to filter possible repairs, was successful at detecting and correcting 80\\% of the repairs, without using prosodic information or a parser.

  6. Multi-Item EPQ Model with Scrap, Rework and Multi-Delivery using Common Cycle Policy

    Directory of Open Access Journals (Sweden)

    S.W. Chiu

    2014-06-01

    Full Text Available This paper is concerned with determining the optimal common production cycle policy for a multi-item economic production quantity (EPQ model with scrap, rework and multiple deliveries. The classic EPQ model considers the optimal replenishment quantity of single product under a perfect production assumption and a continuous inventory issuing policy. However, in real life production planning, manufacturing firms often plan to have multiple products made in turn on a single machine in order to maximize the machine utilization. Also, dealing with random defective items during the production run seems to be an inevitable task, and the multi-delivery policy is commonly adopted for distributing finished items to customers. In this study, we assume a portion of nonconforming items is scrap and the other portion of them can be reworked and repaired in the same production cycle with additional cost. The objective is to determine an optimal common production cycle time that minimizes the long-run average cost per unit time for such a specific multi-item EPQ model with scrap, rework and multi-delivery policy. Mathematical modeling and analysis is used and a closed-form optimal common cycle time for multi-item production planning is obtained. A numerical example is provided to demonstrate the practical usage of research result.

  7. Türkçede Üçüncü Kişide Kişi ve Sayı Özelliklerinin Onarım Tabanlı İncelenmesi A Repair-Based Investigation Of Person And Number Features Of Third Person In Turkish

    Directory of Open Access Journals (Sweden)

    Mehmet AYGÜNEŞ

    2013-07-01

    Full Text Available In syntactic theory, one line of reasoning holds that [person] and[number] features are in the form of bundle features (Chomsky, 1995,2000, 2004, while there are also views supporting the split featuresargument (Sigurðsson, 2004; Baker, 2008; Nevins, 2011, et al.. Inaddition to this distinction between [person] and [number] features, it isargued that there is also a hierarchical structure within the [person]feature and considering the cross-linguistic perspective, there is a1/2>3 [person] hierarchy (Benveniste, 1966; Silverstein, 1985;Carminati, 2005; Bianchi, 2006. The present study aims to understandwhether [person] and [number] features of third person in Turkish aresplit features or not through the repair strategy. Furthermore, the datacollected in this study have been combined with that of Aygüneş (2012,2013 and a second analysis was performed. The aim of this analysiswas to identify the differences reflected to the repair process in personand number categories of the first and third person. Seventyparticipants took part in the study. The participants were presentedwith three sentence types including person, number, and both personand number mismatches between DP (Determiner Phrase and To head(Tense Head and were asked to correct these sentences. The resultsrevealed that participants repaired sentences containing mismatch onthe basis of the DP at a higher rate and word order did not influence therepair process. Moreover, a difference was observed in the repair ofmismatches in the person and number categories in the third person.This finding is line with the argument that [person] and [number] aresplit features. When the present data were combined with data fromAygüneş (2012, 2013, a difference was observed between first and thirdperson in the repair process, which stems from the number category.While the number category interacted with DP and To head at a similarrate in the first person, it interacted with the DP at a higher rate in

  8. Sagan numbers

    OpenAIRE

    Mendonça, J. Ricardo G.

    2012-01-01

    We define a new class of numbers based on the first occurrence of certain patterns of zeros and ones in the expansion of irracional numbers in a given basis and call them Sagan numbers, since they were first mentioned, in a special case, by the North-american astronomer Carl E. Sagan in his science-fiction novel "Contact." Sagan numbers hold connections with a wealth of mathematical ideas. We describe some properties of the newly defined numbers and indicate directions for further amusement.

  9. Fibonacci numbers

    CERN Document Server

    Vorob'ev, Nikolai Nikolaevich

    2011-01-01

    Fibonacci numbers date back to an 800-year-old problem concerning the number of offspring born in a single year to a pair of rabbits. This book offers the solution and explores the occurrence of Fibonacci numbers in number theory, continued fractions, and geometry. A discussion of the ""golden section"" rectangle, in which the lengths of the sides can be expressed as a ration of two successive Fibonacci numbers, draws upon attempts by ancient and medieval thinkers to base aesthetic and philosophical principles on the beauty of these figures. Recreational readers as well as students and teacher

  10. Number names and number understanding

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    2014-01-01

    through using mathematical names for the numbers such as one-ten-one for 11 and five-ten-six for 56. The project combines the renaming of numbers with supporting the teaching with the new number names. Our hypothesis is that Danish children have more difficulties learning and working with numbers, because...... the Danish number names are more complicated than in other languages. Keywords: A research project in grade 0 and 1th in a Danish school, Base-10 system, two-digit number names, semiotic, cognitive perspectives....

  11. Groin hernia repair in young males: mesh or sutured repair?

    DEFF Research Database (Denmark)

    Bisgaard, T; Bay-Nielsen, M; Kehlet, H

    2010-01-01

    Large-scale data for the optimal inguinal hernia repair in younger men with an indirect hernia is not available. We analysed nationwide data for risk of reoperation in younger men after a primary repair using a Lichtenstein operation or a conventional non-mesh hernia repair....

  12. 41 CFR 101-30.701-2 - Item standardization code.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Item standardization code....7-Item Reduction Program § 101-30.701-2 Item standardization code. Item standardization code (ISC) means a code assigned an item in the supply system which identifies the item as authorized...

  13. Detection of Differential Item Functioning Using the Lasso Approach

    Science.gov (United States)

    Magis, David; Tuerlinckx, Francis; De Boeck, Paul

    2015-01-01

    This article proposes a novel approach to detect differential item functioning (DIF) among dichotomously scored items. Unlike standard DIF methods that perform an item-by-item analysis, we propose the "LR lasso DIF method": logistic regression (LR) model is formulated for all item responses. The model contains item-specific intercepts,…

  14. Cleft lip and palate repair

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/002979.htm Cleft lip and palate repair To use the sharing features on this page, please enable JavaScript. Cleft lip and cleft palate repair is surgery to fix birth defects ...

  15. Abdominal aortic aneurysm repair - open

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007392.htm Abdominal aortic aneurysm repair - open To use the sharing features on this page, please enable JavaScript. Open abdominal aortic aneurysm repair is surgery to fix a widened part ...

  16. Wellbore Seal Repair Using Nanocomposite Materials

    Energy Technology Data Exchange (ETDEWEB)

    Stormont, John [Univ. of New Mexico, Albuquerque, NM (United States)

    2016-08-31

    Nanocomposite wellbore repair materials have been developed, tested, and modeled through an integrated program of laboratory testing and numerical modeling. Numerous polymer-cement nanocomposites were synthesized as candidate wellbore repair materials using various combinations of base polymers and nanoparticles. Based on tests of bond strength to steel and cement, ductility, stability, flowability, and penetrability in opening of 50 microns and less, we identified Novolac epoxy reinforced with multi-walled carbon nanotubes and/or alumina nanoparticles to be a superior wellbore seal material compared to conventional microfine cements. A system was developed for testing damaged and repaired wellbore specimens comprised of a cement sheath cast on a steel casing. The system allows independent application of confining pressures and casing pressures while gas flow is measured through the specimens along the wellbore axis. Repair with the nanocomposite epoxy base material was successful in dramatically reducing the flow through flaws of various sizes and types, and restoring the specimen comparable to an intact condition. In contrast, repair of damaged specimens with microfine cement was less effective, and the repair degraded with application of stress. Post-test observations confirm the complete penetration and sealing of flaws using the nanocomposite epoxy base material. A number of modeling efforts have supported the material development and testing efforts. We have modeled the steel-repair material interface behavior in detail during slant shear tests, which we used to characterize bond strength of candidate repair materials. A numerical model of the laboratory testing of damaged wellbore specimens was developed. This investigation found that microannulus permeability can satisfactorily be described by a joint model. Finally, a wellbore model has been developed that can be used to evaluate the response of the wellbore system (casing, cement, and microannulus

  17. An Integrated Vendor-Buyer Cooperative Inventory Model for Items with Imperfect Quality and Shortage Backordering

    Directory of Open Access Journals (Sweden)

    Jia-Tzer Hsu

    2012-01-01

    Full Text Available We develop a model to determine an integrated vendor-buyer inventory policy for items with imperfect quality and planned backorders. The production process is imperfect and produces a certain number of defective items with a known probability density function. The vendor delivers the items to the buyer in small lots of equally sized shipments. Upon receipt of the items, the buyer will conduct a 100% inspection. Since each lot contains a variable number of defective items, shortages may occur at the buyer. We assume that shortages are permitted and are completely backordered. The objective is to minimize the total joint annual costs incurred by the vendor and the buyer. The expected total annual integrated cost is derived and a solution procedure is provided to find the optimal solution. Numerical examples show that the integrated model gives an impressive cost reduction in comparison to an independent decision by the buyer.

  18. An Item Analysis and Validity Investigation of Bender Visual Motor Gestalt Test Score Items

    Science.gov (United States)

    Lambert, Nadine M.

    1971-01-01

    This investigation attempted to demonstrate the utility of standard item analysis procedures for selecting the most reliable and valid items for scoring Bender Visual Motor Gestalt Test test records. (Author)

  19. 76 FR 60474 - Commercial Item Handbook

    Science.gov (United States)

    2011-09-29

    ... Defense Acquisition Regulations System Commercial Item Handbook AGENCY: Defense Acquisition Regulations... Commercial Item Handbook. The purpose of the Handbook is to help acquisition personnel develop sound business... the Handbook. DATES: Comments should be submitted in writing to the address shown below on or before...

  20. Item nonresponse in questionnaire research with children

    NARCIS (Netherlands)

    Hox, J.J.; Borgers, N.

    2001-01-01

    This study investigates the effect of item and person characteristics on item nonresponse, for written questionnaires used with school children. Secondary analyses were done on questionnaire data collected in five distinct studies. To analyze the data, logistic multilevel analysis was used with the

  1. Restricted Interests and Teacher Presentation of Items

    Science.gov (United States)

    Stocco, Corey S.; Thompson, Rachel H.; Rodriguez, Nicole M.

    2011-01-01

    Restricted and repetitive behavior (RRB) is more pervasive, prevalent, frequent, and severe in individuals with autism spectrum disorders (ASDs) than in their typical peers. One subtype of RRB is restricted interests in items or activities, which is evident in the manner in which individuals engage with items (e.g., repetitious wheel spinning),…

  2. Item Calibration in Incomplete Testing Designs

    Science.gov (United States)

    Eggen, Theo J. H. M.; Verhelst, Norman D.

    2011-01-01

    This study discusses the justifiability of item parameter estimation in incomplete testing designs in item response theory. Marginal maximum likelihood (MML) as well as conditional maximum likelihood (CML) procedures are considered in three commonly used incomplete designs: random incomplete, multistage testing and targeted testing designs.…

  3. 38 CFR 3.1606 - Transportation items.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Transportation items. 3... Burial Benefits § 3.1606 Transportation items. The transportation costs of those persons who come within... shipment. (6) Cost of transportation by common carrier including amounts paid as Federal taxes. (7) Cost...

  4. Interservice Availability of Multiservice Used Items.

    Science.gov (United States)

    1999-05-14

    t PIVT OF DISTRIBUTION STATEMENT A Approved for Public Releaseo r. Distribution Unlimited 19990817 034 INTERSERVICE AVAILABILTY OF MULTISERVICE USED...was initially cataloged or placed in the DoD supply system. As items matured, that is, as recurring item costs, usage rates, and technological

  5. Nanomaterials promise better bone repair

    OpenAIRE

    Qifei Wang; Jianhua Yan; Junlin Yang; Bingyun Li

    2016-01-01

    Nanomaterials mimicking the nano-features of bones and offering unique smart functions are promising for better bone fracture repair. This review provides an overview of the current state-of-the-art research in developing and using nanomaterials for better bone fracture repair. This review begins with a brief introduction of bone fracture repair processes, then discusses the importance of vascularization, the role of growth factors in bone fracture repair, and the failure of bone fracture rep...

  6. Laparoscopic repair of femoral hernia

    OpenAIRE

    Yang, Xue-Fei; Liu, Jia-Lin

    2016-01-01

    Laparoscopic repair of inguinal hernia is mini-invasive and has confirmed effects. Femoral hernia could be repaired through the laparoscopic procedures for inguinal hernia. These procedures have clear anatomic view in the operation and preoperatively undiagnosed femoral hernia could be confirmed and treated. Lower recurrence ratio was reported in laparoscopic procedures compared with open procedures for repair of femoral hernia. The technical details of laparoscopic repair of femoral hernia, ...

  7. On finding similar items in a stream of transactions

    DEFF Research Database (Denmark)

    Campagna, Andrea; Pagh, Rasmus

    2010-01-01

    While there has been a lot of work on finding frequent itemsets in transaction data streams, none of these solve the problem of finding similar pairs according to standard similarity measures. This paper is a first attempt at dealing with this, arguably more important, problem. We start out......(\\min\\{mb,n^k,(mb/\\varphi)^k\\})$ bits, where $mb$ is the number of items in the stream so far, $n$ is the number of distinct items and $\\varphi$ is a support threshold. To achieve any non-trivial space upper bound we must thus abandon a worst-case assumption on the data stream. We work under the model that the transactions come...... in random order, and show that surprisingly, not only is small-space similarity mining possible for the most common similarity measures, but the mining accuracy {\\em improves\\/} with the length of the stream for any fixed support threshold....

  8. Eulerian numbers

    CERN Document Server

    Petersen, T Kyle

    2015-01-01

    This text presents the Eulerian numbers in the context of modern enumerative, algebraic, and geometric combinatorics. The book first studies Eulerian numbers from a purely combinatorial point of view, then embarks on a tour of how these numbers arise in the study of hyperplane arrangements, polytopes, and simplicial complexes. Some topics include a thorough discussion of gamma-nonnegativity and real-rootedness for Eulerian polynomials, as well as the weak order and the shard intersection order of the symmetric group. The book also includes a parallel story of Catalan combinatorics, wherein the Eulerian numbers are replaced with Narayana numbers. Again there is a progression from combinatorics to geometry, including discussion of the associahedron and the lattice of noncrossing partitions. The final chapters discuss how both the Eulerian and Narayana numbers have analogues in any finite Coxeter group, with many of the same enumerative and geometric properties. There are four supplemental chapters throughout, ...

  9. Aircraft Propeller Hub Repair

    Energy Technology Data Exchange (ETDEWEB)

    Muth, Thomas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Peter, William H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-02-13

    The team performed a literature review, conducted residual stress measurements, performed failure analysis, and demonstrated a solid state additive manufacturing repair technique on samples removed from a scrapped propeller hub. The team evaluated multiple options for hub repair that included existing metal buildup technologies that the Federal Aviation Administration (FAA) has already embraced, such as cold spray, high velocity oxy-fuel deposition (HVOF), and plasma spray. In addition the team helped Piedmont Propulsion Systems, LLC (PPS) evaluate three potential solutions that could be deployed at different stages in the life cycle of aluminum alloy hubs, in addition to the conventional spray coating method for repair. For new hubs, a machining practice to prevent fretting with the steel drive shaft was recommended. For hubs that were refurbished with some material remaining above the minimal material condition (MMC), a silver interface applied by an electromagnetic pulse additive manufacturing method was recommended. For hubs that were at or below the MMC, a solid state additive manufacturing technique using ultrasonic welding (UW) of thin layers of 7075 aluminum to the hub interface was recommended. A cladding demonstration using the UW technique achieved mechanical bonding of the layers showing promise as a viable repair method.

  10. Neural measures reveal a fixed item limit in subitizing.

    Science.gov (United States)

    Ester, Edward F; Drew, Trafton; Klee, Daniel; Vogel, Edward K; Awh, Edward

    2012-05-23

    For centuries, it has been known that humans can rapidly and accurately enumerate small sets of items, a process referred to as subitizing. However, there is still active debate regarding the mechanisms that mediate this ability. For example, some have argued that subitizing reflects the operation of a fixed-capacity individuation mechanism that enables concurrent access to a small number of items. However, others have argued that subitizing reflects the operation of a continuous numerical estimation mechanism whose precision varies with numerosity in a manner consistent with Weber's law. Critically, quantitative models based on either of these predictions can provide a reasonable description of subitizing performance, making it difficult to discriminate between these alternatives solely on the basis of subjects' behavioral performance. Here, we attempted to discriminate between fixed-capacity and continuous estimation models of subitizing using neural measures. In two experiments, we recorded EEGs while subjects performed a demanding subitizing task and examined set-size-dependent changes in a neurophysiological marker of visual selection (the N2pc event-related potential component) evoked by an array of to-be-enumerated items. In both experiments, N2pc amplitudes increased monotonically within the subitizing range before reaching an asymptotic limit at approximately three items. Moreover, inter-participant differences in the location of this asymptote were strongly predictive of behavioral estimates of subitizing span derived from a fixed-capacity model. Thus, neural activity linked with subitizing ability shows evidence of an early and discrete limit in the number of items that can be concurrently apprehended, supporting a fixed-capacity model of this process.

  11. 76 FR 68675 - Revisions to the Export Administration Regulations (EAR): Control of Aircraft and Related Items...

    Science.gov (United States)

    2011-11-07

    ... Administration Regulations (EAR): Control of Aircraft and Related Items the President Determines No Longer... Portal: http://www.regulations.gov . The identification number for this rulemaking is BIS-2011-0033. By...

  12. The use of an item response theory-based disability item bank across diseases: accounting for differential item functioning.

    Science.gov (United States)

    Weisscher, Nadine; Glas, Cees A; Vermeulen, Marinus; De Haan, Rob J

    2010-05-01

    There is not a single universally accepted activity of daily living (ADL) instrument available to compare disability assessments across different patient groups. We developed a generic item bank of ADL items using item response theory, the Academic Medical Center Linear Disability Scale (ALDS). When comparing outcomes of the ALDS between patients groups, item characteristics of the ALDS should be comparable across groups. The aim of the study was to assess the differential item functioning (DIF) in a group of patients with various disorders to investigate the comparability across these groups. Cross-sectional, multicenter study including 1,283 in- and outpatients with a variety of disorders and disability levels. The sample was divided in two groups: (1) mainly neurological patients (n=497; vascular medicine, Parkinson's disease and neuromuscular disorders) and (2) patients from internal medicine (n=786; pulmonary diseases, chronic pain, rheumatoid arthritis, and geriatric patients). Eighteen of 72 ALDS items showed statistically significant DIF (P<0.01). However, the DIF could effectively be modeled by the introduction of disease-specific parameters. In the subgroups studied, DIF could be modeled in such a way that the ensemble of the items comprised a scale applicable in both groups.

  13. TRACTOR REPAIR. AGRICULTURAL MACHINERY--SERVICE OCCUPATIONS, MODULE NUMBER 16.

    Science.gov (United States)

    Ohio State Univ., Columbus. Center for Vocational and Technical Education.

    THE PURPOSE OF THIS GUIDE IS TO HELP TEACHERS PREPARE POSTSECONDARY STUDENTS FOR THE AGRICULTURAL MACHINERY SERVICE OCCUPATIONS AS PARTS MEN, MECHANICS, MECHANIC'S HELPERS, AND SERVICE SUPERVISORS. IT WAS DESIGNED BY A NATIONAL TASK FORCE ON THE BASIS OF RESEARCH FROM STATE STUDIES. THE MAJOR OBJECTIVE IS TO DEVELOP (1) AN UNDERSTANDING OF THE…

  14. AN ITEM RESPONSE MODEL WITH SINGLE PEAKED ITEM CHARACTERISTIC CURVES - THE PARELLA MODEL

    NARCIS (Netherlands)

    HOIJTINK, H; MOLENAAR, [No Value

    In this paper an item response model (the PARELLA model) designed specifically for the measurement of attitudes and preferences will be introduced. In contrast with the item response models currently used (e.g. the Rasch model and, the two and three parameter logistic model) the item characteristic

  15. Comparing Methods for Item Analysis: The Impact of Different Item-Selection Statistics on Test Difficulty

    Science.gov (United States)

    Jones, Andrew T.

    2011-01-01

    Practitioners often depend on item analysis to select items for exam forms and have a variety of options available to them. These include the point-biserial correlation, the agreement statistic, the B index, and the phi coefficient. Although research has demonstrated that these statistics can be useful for item selection, no research as of yet has…

  16. Developing and evaluating innovative items for the NCLEX: Part 2, item characteristics and cognitive processing.

    Science.gov (United States)

    Wendt, Anne; Harmes, J Christine

    2009-01-01

    This article is a continuation of the research on the development and evaluation of innovative item formats for the NCLEX examinations that was published in the March/April 2009 edition of Nurse Educator. The authors discuss the innovative item templates and evaluate the statistical characteristics and level of cognitive processing required to answer the examination items.

  17. Ramsay-Curve Item Response Theory for the Three-Parameter Logistic Item Response Model

    Science.gov (United States)

    Woods, Carol M.

    2008-01-01

    In Ramsay-curve item response theory (RC-IRT), the latent variable distribution is estimated simultaneously with the item parameters of a unidimensional item response model using marginal maximum likelihood estimation. This study evaluates RC-IRT for the three-parameter logistic (3PL) model with comparisons to the normal model and to the empirical…

  18. Evaluation of Northwest University, Kano Post-UTME Test Items Using Item Response Theory

    Science.gov (United States)

    Bichi, Ado Abdu; Hafiz, Hadiza; Bello, Samira Abdullahi

    2016-01-01

    High-stakes testing is used for the purposes of providing results that have important consequences. Validity is the cornerstone upon which all measurement systems are built. This study applied the Item Response Theory principles to analyse Northwest University Kano Post-UTME Economics test items. The developed fifty (50) economics test items was…

  19. Assessment of nasalance and nasality in patients with a repaired cleft palate.

    Science.gov (United States)

    Sinko, Klaus; Gruber, Maike; Jagsch, Reinhold; Roesner, Imme; Baumann, Arnulf; Wutzl, Arno; Denk-Linnert, Doris-Maria

    2017-03-15

    In patients with a repaired cleft palate, nasality is typically diagnosed by speech language pathologists. In addition, there are various instruments to objectively diagnose nasalance. To explore the potential of nasalance measurements after cleft palate repair by NasalView(®), we correlated perceptual nasality and instrumentally measured nasalance of eight speech items and determined the relationship between sensitivity and specificity of the nasalance measures by receiver-operating characteristics (ROC) analyses and AUC (area under the curve) computation for each single test item and specific item groups. We recruited patients with a primarily repaired cleft palate receiving speech therapy during follow-up. During a single day visit, perceptive and instrumental assessments were obtained in 36 patients and analyzed. The individual perceptual nasality was assigned to one of four categories; the corresponding instrumental nasalance measures for the eight specific speech items were expressed on a metric scale (1-100). With reference to the perceptual diagnoses, we observed 3 nasal and one oral test item with high sensitivity. However, the specificity of the nasality indicating measures was rather low. The four best speech items with the highest sensitivity provided scores ranging from 96.43 to 100%, while the averaged sensitivity of all eight items was below 90%. We conclude that perceptive evaluation of nasality remains state of the art. For clinical follow-up, instrumental nasalance assessment can objectively document subtle changes by analysis of four speech items only. Further studies are warranted to determine the applicability of instrumental nasalance measures in the clinical routine, using discriminative items only.

  20. Working memory for sequences of temporal durations reveals a volatile single-item store

    Directory of Open Access Journals (Sweden)

    Sanjay G Manohar

    2016-10-01

    Full Text Available When a sequence is held in working memory, different items are retained with differing fidelity. Here we ask whether a sequence of brief time intervals that must be remembered show recency effects, similar to those observed in verbal and visuospatial working memory. It has been suggested that prioritising some items over others can be accounted for by a focus of attention, maintaining some items in a privileged state. We therefore also investigated whether such benefits are vulnerable to disruption by attention or expectation. Participants listened to sequences of one to five tones, of varying durations (200ms to 2s. Subsequently, the length of one of the tones in the sequence had to be reproduced by holding a key. The discrepancy between the reproduced and actual durations quantified the fidelity of memory for auditory durations. Recall precision decreased with the number of items that had to be remembered, and was better for the first and last items of sequences, in line with set-size and serial position effects seen in other modalities. To test whether attentional filtering demands might impair performance, an irrelevant variation in pitch was introduced in some blocks of trials. In those blocks, memory precision was worse for sequences that consisted of only one item, i.e. the smallest memory set size. Thus, when irrelevant information was present, the benefit of having only one item in memory is attenuated. Finally we examined whether expectation could interfere with memory. On half the trials, the number of items in the upcoming sequence was cued. When the number of items was known in advance, performance was paradoxically worse when the sequence consisted of only one item. Thus the benefit of having only one item to remember is stronger when it is unexpectedly the only item. Our results suggest that similar mechanisms are used to hold auditory time durations in working memory, as for visual or verbal stimuli. Further, solitary items were

  1. No evidence for an item limit in change detection.

    Directory of Open Access Journals (Sweden)

    Shaiyan Keshvari

    Full Text Available Change detection is a classic paradigm that has been used for decades to argue that working memory can hold no more than a fixed number of items ("item-limit models". Recent findings force us to consider the alternative view that working memory is limited by the precision in stimulus encoding, with mean precision decreasing with increasing set size ("continuous-resource models". Most previous studies that used the change detection paradigm have ignored effects of limited encoding precision by using highly discriminable stimuli and only large changes. We conducted two change detection experiments (orientation and color in which change magnitudes were drawn from a wide range, including small changes. In a rigorous comparison of five models, we found no evidence of an item limit. Instead, human change detection performance was best explained by a continuous-resource model in which encoding precision is variable across items and trials even at a given set size. This model accounts for comparison errors in a principled, probabilistic manner. Our findings sharply challenge the theoretical basis for most neural studies of working memory capacity.

  2. Advantages of using volar vein repair in finger replantations.

    Science.gov (United States)

    Mersa, Berkan; Kabakas, Fatih; Pürisa, Hüsrev; Özçelik, Ismail Bülent; Yeşiloğlu, Nebil; Sezer, Ilker; Tunçer, Serdar

    2014-01-01

    Providing adequate venous outflow is essential in finger replantation surgeries. For a successful result, the quality and quantity of venous repairs should be adequate to drain arterial inflow. The digital dorsal venous plexus is a reliable source of material for venous repairs. Classically, volar digital veins have been used only when no other alternative was available. However, repairing volar veins to augment venous outflow has a number of technical advantages and gives a greater chance of survival. Increasing the repaired vein:artery ratio also increases the success of replantation. The volar skin, covering the volar vein, is less likely to be avulsed during injury and is also less likely to turn necrotic, than dorsal skin, after the replantation surgery. Primary repair of dorsal veins can be difficult due to tightness ensuing from arthrodesis of the underlying joint in flexion. In multiple finger replantations, repairing the volar veins after arterial repair and continuing to do so for each finger in the same way without changing the position of the hand and surgeon save time. In amputations with tissue loss, the size discrepancy is less for volar veins than for dorsal veins. We present the results of 366 finger replantations after volar vein repairs.

  3. Refinement of the Brazilian Household Food Insecurity Measurement Scale: Recommendation for a 14-item EBIA

    Directory of Open Access Journals (Sweden)

    Ana Maria Segall-Corrêa

    2014-04-01

    Full Text Available OBJECTIVE: To review and refine Brazilian Household Food Insecurity Measurement Scale structure. METHODS: The study analyzed the impact of removing the item "adult lost weight" and one of two possibly redundant items on Brazilian Household Food Insecurity Measurement Scale psychometric behavior using the one-parameter logistic (Rasch model. Brazilian Household Food Insecurity Measurement Scale psychometric behavior was analyzed with respect to acceptable adjustment values ranging from 0.7 to 1.3, and to severity scores of the items with theoretically expected gradients. The socioeconomic and food security indicators came from the 2004 National Household Sample Survey, which obtained complete answers to Brazilian Household Food Insecurity Measurement Scale items from 112,665 households. RESULTS: Removing the items "adult reduced amount..." followed by "adult ate less..." did not change the infit of the remaining items, except for "adult lost weight", whose infit increased from 1.21 to 1.56. The internal consistency and item severity scores did not change when "adult ate less" and one of the two redundant items were removed. CONCLUSION: Brazilian Household Food Insecurity Measurement Scale reanalysis reduced the number of scale items from 16 to 14 without changing its internal validity. Its use as a nationwide household food security measure is strongly recommended.

  4. Attending multiple items decreases the selectivity of population responses in human primary visual cortex.

    Science.gov (United States)

    Anderson, David E; Ester, Edward F; Serences, John T; Awh, Edward

    2013-05-29

    Multiple studies have documented an inverse relationship between the number of to-be-attended or remembered items in a display ("set size") and task performance. The neural source of this decline in cognitive performance is currently under debate. Here, we used a combination of fMRI and a forward encoding model of orientation selectivity to generate population tuning functions for each of two stimuli while human observers attended either one or both items. We observed (1) clear population tuning functions for the attended item(s) that peaked at the stimulus orientation and decreased monotonically as the angular distance from this orientation increased, (2) a set-size-dependent decline in the relative precision of orientation-specific population responses, such that attending two items yielded a decline in selectivity of the population tuning function for each item, and (3) that the magnitude of the loss of precision in population tuning functions predicted individual differences in the behavioral cost of attending an additional item. These findings demonstrate that attending multiple items degrades the precision of perceptual representations for the target items and provides a straightforward account for the associated impairments in visually guided behavior.

  5. Validation of the Algorithms for Depot Exchangeable Repair and Modification Costs for NSNS and Engines for the Component Support Cost System (D160B).

    Science.gov (United States)

    2014-09-26

    IDENTIFICATION OI 03 NOMENCLATURE . ITEM 012 03 PRICE. STANDARD INVENTORY 013 03 CODE. WEAPON SYSTEM SUPPORT 014 06 CODE. WEAPON SYSTEM SUPPORT. POSITIONS I TO...calculation of standard depot repair prices ( sales prices). Various knowledgeable Air Force personnel have noted that it is not unusual for an engine to be both...cost elements not used in calculation of standard depot repair prices (" sales prices"). ISI affirms the congruence of the definitions of repair prices as

  6. Automatic Identification of Critical Data Items in a Database to Mitigate the Effects of Malicious Insiders

    Science.gov (United States)

    White, Jonathan; Panda, Brajendra

    A major concern for computer system security is the threat from malicious insiders who target and abuse critical data items in the system. In this paper, we propose a solution to enable automatic identification of critical data items in a database by way of data dependency relationships. This identification of critical data items is necessary because insider threats often target mission critical data in order to accomplish malicious tasks. Unfortunately, currently available systems fail to address this problem in a comprehensive manner. It is more difficult for non-experts to identify these critical data items because of their lack of familiarity and due to the fact that data systems are constantly changing. By identifying the critical data items automatically, security engineers will be better prepared to protect what is critical to the mission of the organization and also have the ability to focus their security efforts on these critical data items. We have developed an algorithm that scans the database logs and forms a directed graph showing which items influence a large number of other items and at what frequency this influence occurs. This graph is traversed to reveal the data items which have a large influence throughout the database system by using a novel metric based formula. These items are critical to the system because if they are maliciously altered or stolen, the malicious alterations will spread throughout the system, delaying recovery and causing a much more malignant effect. As these items have significant influence, they are deemed to be critical and worthy of extra security measures. Our proposal is not intended to replace existing intrusion detection systems, but rather is intended to complement current and future technologies. Our proposal has never been performed before, and our experimental results have shown that it is very effective in revealing critical data items automatically.

  7. Calibration of the PROMIS physical function item bank in Dutch patients with rheumatoid arthritis.

    Directory of Open Access Journals (Sweden)

    Martijn A H Oude Voshaar

    Full Text Available OBJECTIVE: To calibrate the Dutch-Flemish version of the PROMIS physical function (PF item bank in patients with rheumatoid arthritis (RA and to evaluate cross-cultural measurement equivalence with US general population and RA data. METHODS: Data were collected from RA patients enrolled in the Dutch DREAM registry. An incomplete longitudinal anchored design was used where patients completed all 121 items of the item bank over the course of three waves of data collection. Item responses were fit to a generalized partial credit model adapted for longitudinal data and the item parameters were examined for differential item functioning (DIF across country, age, and sex. RESULTS: In total, 690 patients participated in the study at time point 1 (T2, N = 489; T3, N = 311. The item bank could be successfully fitted to a generalized partial credit model, with the number of misfitting items falling within acceptable limits. Seven items demonstrated DIF for sex, while 5 items showed DIF for age in the Dutch RA sample. Twenty-five (20% items were flagged for cross-cultural DIF compared to the US general population. However, the impact of observed DIF on total physical function estimates was negligible. DISCUSSION: The results of this study showed that the PROMIS PF item bank adequately fit a unidimensional IRT model which provides support for applications that require invariant estimates of physical function, such as computer adaptive testing and targeted short forms. More studies are needed to further investigate the cross-cultural applicability of the US-based PROMIS calibration and standardized metric.

  8. Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair.

    Science.gov (United States)

    Czornak, Kamila; Chughtai, Sanaullah; Chrzanowska, Krystyna H

    2008-01-01

    Genomes are subject to a number of exogenous or endogenous DNA-damaging agents that cause DNA double-strand breaks (DSBs). These critical DNA lesions can result in cell death or a wide variety of genetic alterations, including deletions, translocations, loss of heterozygosity, chromosome loss, or chromosome fusions, which enhance genome instability and can trigger carcinogenesis. The cells have developed an efficient mechanism to cope with DNA damages by evolving the DNA repair machinery. There are 2 major DSB repair mechanisms: nonhomologous end joining (NHEJ) and homologous recombination (HR). One element of the repair machinery is the MRN complex, consisting of MRE11, RAD50 and NBN (previously described as NBS1), which is involved in DNA replication, DNA repair, and signaling to the cell cycle checkpoints. A number of kinases, like ATM (ataxia-telangiectasia mutated), ATR (ataxia-telangiectasia and Rad-3-related), and DNA PKcs (DNA protein kinase catalytic subunit), phosphorylate various protein targets in order to repair the damage. If the damage cannot be repaired, they direct the cell to apoptosis. The MRN complex as well as repair kinases are also involved in telomere maintenance and genome stability. The dysfunction of particular elements involved in the repair mechanisms leads to genome instability disorders, like ataxia telangiectasia (A-T), A-T-like disorder (ATLD) and Nijmegen breakage syndrome (NBS). The mutated genes responsible for these disorders code for proteins that play key roles in the process of DNA repair. Here we present a detailed review of current knowledge on the MRN complex, kinases engaged in DNA repair, and genome instability disorders.

  9. Measuring student learning with item response theory

    Directory of Open Access Journals (Sweden)

    Young-Jin Lee

    2008-01-01

    Full Text Available We investigate short-term learning from hints and feedback in a Web-based physics tutoring system. Both the skill of students and the difficulty and discrimination of items were determined by applying item response theory (IRT to the first answers of students who are working on for-credit homework items in an introductory Newtonian physics course. We show that after tutoring a shifted logistic item response function with lower discrimination fits the students’ second responses to an item previously answered incorrectly. Student skill decreased by 1.0 standard deviation when students used no tutoring between their (incorrect first and second attempts, which we attribute to “item-wrong bias.” On average, using hints or feedback increased students’ skill by 0.8 standard deviation. A skill increase of 1.9 standard deviation was observed when hints were requested after viewing, but prior to attempting to answer, a particular item. The skill changes measured in this way will enable the use of IRT to assess students based on their second attempt in a tutoring environment.

  10. Item response theory for measurement validity.

    Science.gov (United States)

    Yang, Frances M; Kao, Solon T

    2014-06-01

    Item response theory (IRT) is an important method of assessing the validity of measurement scales that is underutilized in the field of psychiatry. IRT describes the relationship between a latent trait (e.g., the construct that the scale proposes to assess), the properties of the items in the scale, and respondents' answers to the individual items. This paper introduces the basic premise, assumptions, and methods of IRT. To help explain these concepts we generate a hypothetical scale using three items from a modified, binary (yes/no) response version of the Center for Epidemiological Studies-Depression scale that was administered to 19,399 respondents. We first conducted a factor analysis to confirm the unidimensionality of the three items and then proceeded with Mplus software to construct the 2-Parameter Logic (2-PL) IRT model of the data, a method which allows for estimates of both item discrimination and item difficulty. The utility of this information both for clinical purposes and for scale construction purposes is discussed.

  11. Magic Numbers

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    THE last digit of my home phone number in Beijing is 4. “So what?” European readers might ask.This was my attitude when I first lived in China; I couldn't understand why Chinese friends were so shocked at my indifference to the number 4. But China brings new discoveries every day, and I have since seen the light. I know now that Chinese people have their own ways of preserving their well being, and that they see avoiding the number 4 as a good way to stay safe.

  12. Number theory

    CERN Document Server

    Andrews, George E

    1994-01-01

    Although mathematics majors are usually conversant with number theory by the time they have completed a course in abstract algebra, other undergraduates, especially those in education and the liberal arts, often need a more basic introduction to the topic.In this book the author solves the problem of maintaining the interest of students at both levels by offering a combinatorial approach to elementary number theory. In studying number theory from such a perspective, mathematics majors are spared repetition and provided with new insights, while other students benefit from the consequent simpl

  13. Bookmark locations and item response model selection in the presence of local item dependence.

    Science.gov (United States)

    Skaggs, Gary

    2007-01-01

    The bookmark standard setting procedure is a popular method for setting performance standards on state assessment programs. This study reanalyzed data from an application of the bookmark procedure to a passage-based test that used the Rasch model to create the item ordered booklet. Several problems were noted in this implementation of the bookmark procedure, including disagreement among the SMEs about the correct order of items in the bookmark booklet, performance level descriptions of the passing standard being based on passage difficulty as well as item difficulty, and the presence of local item dependence within reading passages. Bookmark item locations were recalculated for the IRT three-parameter model and the multidimensional bifactor model. The results showed that the order of item locations was very similar for all three models when items of high difficulty and low discrimination were excluded. However, the items whose positions were the most discrepant between models were not the items that the SMEs disagreed about the most in the original standard setting. The choice of latent trait model did not address problems of item order disagreement. Implications for the use of the bookmark method in the presence of local item dependence are discussed.

  14. Nanomaterials promise better bone repair

    Directory of Open Access Journals (Sweden)

    Qifei Wang

    2016-10-01

    Full Text Available Nanomaterials mimicking the nano-features of bones and offering unique smart functions are promising for better bone fracture repair. This review provides an overview of the current state-of-the-art research in developing and using nanomaterials for better bone fracture repair. This review begins with a brief introduction of bone fracture repair processes, then discusses the importance of vascularization, the role of growth factors in bone fracture repair, and the failure of bone fracture repair. Next, the review discusses the applications of nanomaterials for bone fracture repair, with a focus on the recent breakthroughs such as nanomaterials leading to precise immobilization of growth factors at the molecular level, promoting vascularization without the use of growth factors, and re-loading therapeutic agents after implantation. The review concludes with perspectives on challenges and future directions for developing nanomaterials for improved bone fracture repair.

  15. Repair and enumeration of injured coliforms in frozen foods.

    Science.gov (United States)

    Warseck, M; Ray, B; Speck, M L

    1973-12-01

    Two strains of Escherichia coli manifested death and repairable injury after being frozen in water or sterile foods at -20 C. The injured survivors were inhibited from forming colonies on violet red bile agar (VRBA) or deoxycholate lactose agar; this inhibition was greater when enumeration was done by the pour plate method instead of the surface or surface-overlay method. Injured cells repaired rapidly in Trypticase soy broth (TSB), and the repair was about maximum after 1 h at 25 C. When the injured cells were added to different foods and incubated at 25 C, repair also occurred; however, recovery was better and more uniform when the samples were mixed with TSB and incubated 1 h at 25 C. Cell multiplication was not evident until after 90 to 120 min at 25 C. The enumeration of coliforms from commercially frozen foods was increased when the thawed samples were mixed with TSB and the cells were allowed to repair 1 h at 25 C. In some samples, the repair permitted at least a 20-fold increase in the coliform count. The associated flora in the commercially frozen foods gave no evidence of impairing the repair of coliforms, nor did they start multiplication prior to 90 min after being incubated in TSB at 25 C. Generally, the plating gave more reproducible recovery of coliforms than did the most probable number method. Also, a higher number of coliforms were obtained by the surface-overlay method of plating using VRBA.

  16. Sequential item pricing for unlimited supply

    OpenAIRE

    2010-01-01

    We investigate the extent to which price updates can increase the revenue of a seller with little prior information on demand. We study prior-free revenue maximization for a seller with unlimited supply of n item types facing m myopic buyers present for k < log n days. For the static (k = 1) case, Balcan et al. [2] show that one random item price (the same on each item) yields revenue within a \\Theta(log m + log n) factor of optimum and this factor is tight. We define the hereditary maximizer...

  17. Nice numbers

    CERN Document Server

    Barnes, John

    2016-01-01

    In this intriguing book, John Barnes takes us on a journey through aspects of numbers much as he took us on a geometrical journey in Gems of Geometry. Similarly originating from a series of lectures for adult students at Reading and Oxford University, this book touches a variety of amusing and fascinating topics regarding numbers and their uses both ancient and modern. The author intrigues and challenges his audience with both fundamental number topics such as prime numbers and cryptography, and themes of daily needs and pleasures such as counting one's assets, keeping track of time, and enjoying music. Puzzles and exercises at the end of each lecture offer additional inspiration, and numerous illustrations accompany the reader. Furthermore, a number of appendices provides in-depth insights into diverse topics such as Pascal’s triangle, the Rubik cube, Mersenne’s curious keyboards, and many others. A theme running through is the thought of what is our favourite number. Written in an engaging and witty sty...

  18. A matter of life or death: modeling DNA damage and repair in bacteria.

    Science.gov (United States)

    Karschau, Jens; de Almeida, Camila; Richard, Morgiane C; Miller, Samantha; Booth, Ian R; Grebogi, Celso; de Moura, Alessandro P S

    2011-02-16

    DNA damage is a hazard all cells must face, and evolution has created a number of mechanisms to repair damaged bases in the chromosome. Paradoxically, many of these repair mechanisms can create double-strand breaks in the DNA molecule which are fatal to the cell. This indicates that the connection between DNA repair and death is far from straightforward, and suggests that the repair mechanisms can be a double-edged sword. In this report, we formulate a mathematical model of the dynamics of DNA damage and repair, and we obtain analytical expressions for the death rate. We predict a counterintuitive relationship between survival and repair. We can discriminate between two phases: below a critical threshold in the number of repair enzymes, the half-life decreases with the number of repair enzymes, but becomes independent of the number of repair enzymes above the threshold. We are able to predict quantitatively the dependence of the death rate on the damage rate and other relevant parameters. We verify our analytical results by simulating the stochastic dynamics of DNA damage and repair. Finally, we also perform an experiment with Escherichia coli cells to test one of the predictions of our model.

  19. Prediction in the Processing of Repair Disfluencies: Evidence from the Visual-World Paradigm

    Science.gov (United States)

    Lowder, Matthew W.; Ferreira, Fernanda

    2016-01-01

    Two visual-world eye-tracking experiments investigated the role of prediction in the processing of repair disfluencies (e.g., "The chef reached for some salt uh I mean some ketchup ..."). Experiment 1 showed that listeners were more likely to fixate a critical distractor item (e.g., "pepper") during the processing of repair…

  20. Repair of ultraviolet-light-induced damage

    Energy Technology Data Exchange (ETDEWEB)

    Sutherland, B.M.

    1981-01-01

    Studies are reviewed which present three major new findings in the photobiology of skin. First, detectable numbers of dimers are formed even at sub-erythymal doses. Second, excision of dimers is much more rapid than would be predicted from results obtained in cell culture. Third, comparison of the rates of excision and photoreactivation in skin indicates that in normal sunlight exposure, photoreactivation may well be the predominant repair pathway in skin. (ACR)

  1. A supplier-selection model with classification and joint replenishment of inventory items

    Science.gov (United States)

    Mohammaditabar, Davood; Hassan Ghodsypour, Seyed

    2016-06-01

    Since inventory costs are closely related to suppliers, many models in the literature have selected the suppliers and also allocated orders, simultaneously. Such models usually consider either a single inventory item or multiple inventory items which have independent holding and ordering costs. However, in practice, ordering multiple items from the same supplier leads to a reduction in ordering costs. This paper presents a model in capacity-constrained supplier-selection and order-allocation problem, which considers the joint replenishment of inventory items with a direct grouping approach. In such supplier-selection problems, the following items are considered: a fixed major ordering cost to each supplier, which is independent from the items in the order; a minor ordering cost for each item ordered to each supplier; and the inventory holding and purchasing costs. To solve the developed NP-hard problem, a simulated annealing algorithm was proposed and then compared to a modified genetic algorithm of the literature. The numerical example represented that the number of groups and selected suppliers were reduced when the major ordering cost increased in comparison to other costs. There were also more savings when the number of groups was determined by the model in comparison to predetermined number of groups or no grouping scenarios.

  2. Repair vs replacement of direct composite restorations: a survey of teaching and operative techniques in Oceania.

    Science.gov (United States)

    Brunton, Paul A; Ghazali, Amna; Tarif, Zahidah H; Loch, Carolina; Lynch, Christopher; Wilson, Nairn; Blum, Igor R

    2017-04-01

    To evaluate the teaching and operative techniques for the repair and/or replacement of direct resin-based composite restorations (DCRs) in dental schools in Oceania. A 14-item questionnaire was mailed to the heads of operative dentistry in 16 dental schools in Oceania (Australia, New Zealand, Fiji and Papua New Guinea). The survey asked whether the repair of DCRs was taught within the curriculum; the rationale behind the teaching; how techniques were taught, indications for repair, operative techniques, materials used, patient acceptability, expected longevity and recall systems. All 16 schools participated in the study. Thirteen (81%) reported the teaching of composite repairs as an alternative to replacement. Most schools taught the theoretical and practical aspects of repair at a clinical level only. All 13 schools (100%) agreed on tooth substance preservation being the main reason for teaching repair. The main indications for repair were marginal defects (100%), followed by secondary caries (69%). All 13 schools that performed repairs reported high patient acceptability, and considered it a definitive measure. Only three schools (23%) claimed to have a recall system in place following repair of DCRs. Most respondents either did not know or did not answer when asked about the longevity of DCRs. Repair of DCRs seems to be a viable alternative to replacement, which is actively taught within Oceania. Advantages include it being minimally invasive, preserving tooth structure, and time and money saving. However, standardised guidelines need to be developed and further clinical long-term studies need to be carried out. The decision between replacing or repairing a defective composite restoration tends to be based on what clinicians have been taught, tempered by experience and judgement. This study investigated the current status of teaching and operative techniques of repair of direct composite restorations in dental schools in Oceania. Copyright © 2017 Elsevier Ltd

  3. National Hospice Item Set (HIS) data

    Data.gov (United States)

    U.S. Department of Health & Human Services — This data set includes the national averages (mean) for quality measure scores of Medicare-certified hospice agencies calculated from the Hospice Item Set (HIS) for...

  4. The Analysis of The Multiple Choice Item

    Institute of Scientific and Technical Information of China (English)

    曹吴惠

    2009-01-01

    In this article, the author analyzes in detail the advantages, disadvantages and forming of the multiple choice item in examinations. On its basis, the author also exploree some aspects the teacher should pay attention to while setting an examination paper.

  5. Extending Item Response Theory to Online Homework

    CERN Document Server

    Kortemeyer, Gerd

    2014-01-01

    Item Response Theory becomes an increasingly important tool when analyzing ``Big Data'' gathered from online educational venues. However, the mechanism was originally developed in traditional exam settings, and several of its assumptions are infringed upon when deployed in the online realm. For a large enrollment physics course for scientists and engineers, the study compares outcomes from IRT analyses of exam and homework data, and then proceeds to investigate the effects of each confounding factor introduced in the online realm. It is found that IRT yields the correct trends for learner ability and meaningful item parameters, yet overall agreement with exam data is moderate. It is also found that learner ability and item discrimination is over wide ranges robust with respect to model assumptions and introduced noise, less so than item difficulty.

  6. Basic Stand Alone Carrier Line Items PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — This release contains the Basic Stand Alone (BSA) Carrier Line Items Public Use Files (PUF) with information from Medicare Carrier claims. The CMS BSA Carrier Line...

  7. Calorimetry of low mass Pu239 items

    Energy Technology Data Exchange (ETDEWEB)

    Cremers, Teresa L [Los Alamos National Laboratory; Sampson, Thomas E [Los Alamos National Laboratory

    2010-01-01

    Calorimetric assay has the reputation of providing the highest precision and accuracy of all nondestructive assay measurements. Unfortunately, non-destructive assay practitioners and measurement consumers often extend, inappropriately, the high precision and accuracy of calorimetric assay to very low mass items. One purpose of this document is to present more realistic expectations for the random uncertainties associated with calorimetric assay for weapons grade plutonium items with masses of 200 grams or less.

  8. New developments in reprocessing semicritical items.

    Science.gov (United States)

    Rutala, William A; Weber, David J

    2013-05-01

    Semicritical medical devices are defined as items that come into contact with mucous membranes or nonintact skin (eg, gastrointestinal endoscopes). Such medical devices require minimally high-level disinfection. Because many of these items are temperature sensitive, low-temperature chemical methods must be used rather than steam sterilization. Strict adherence to current guidelines is required because more outbreaks have been linked to inadequately cleaned or disinfected endoscopes undergoing high-level disinfection than any other medical device.

  9. A Review of Test Item Types

    Science.gov (United States)

    2008-03-06

    for integration with the CAT- ASVAB as it exists now. The CAT-ASVAB currently employs only dichotomously scored items using the 3 parameter logistic ...model ( 3PL ; Lord & Novick, 1968). IRT models appropriate for polytomously scored items (e.g., Muraki, 1997) are available, and mixing of models is not...problematic within the IRT framework per se. Nevertheless, the current CAT-ASVAB infrastructure is configured to work with the 3PL model only, and

  10. Transcendental numbers

    CERN Document Server

    Murty, M Ram

    2014-01-01

    This book provides an introduction to the topic of transcendental numbers for upper-level undergraduate and graduate students. The text is constructed to support a full course on the subject, including descriptions of both relevant theorems and their applications. While the first part of the book focuses on introducing key concepts, the second part presents more complex material, including applications of Baker’s theorem, Schanuel’s conjecture, and Schneider’s theorem. These later chapters may be of interest to researchers interested in examining the relationship between transcendence and L-functions. Readers of this text should possess basic knowledge of complex analysis and elementary algebraic number theory.

  11. Laparoscopic repair of urogenital fistulae: A single centre experience

    Directory of Open Access Journals (Sweden)

    Sumit Sharma

    2014-01-01

    Full Text Available Context: Sparse literature exists on laparoscopic repair of urogenital fistulae (UGF. Aims: The purpose of the following study is to report our experience of laparoscopic UGF repair with emphasis on important steps for a successful laparoscopic repair. Settings And Design: Data of patients who underwent laparoscopic repair of UGF from 2003 to 2012 was retrospectively reviewed. Materials and Methods: Data was reviewed as to the aetiology, prior failed attempts, size, number and location of fistula, mean operative time, blood loss, post-operative storage/voiding symptoms and episodes of urinary tract infections (UTI. Results: Laparoscopic repair of 22 supratrigonal vesicovaginal fistulae (VVF (five recurrent and 31 ureterovaginal fistulae (UVF was performed. VVF followed transabdominal hysterectomy (14, lower segment caesarean section (LSCS (7 and oophrectomy (1. UVF followed laparoscopy assisted vaginal hysterectomy (18, transvaginal hysterectomy (2 and transabdominal hysterectomy (10 and LSCS (1. Mean VVF size was 14 mm. Mean operative time and blood loss for VVF and UVF were 140 min, 75 ml and 130 min, 60 ml respectively. In 20 VVF repairs tissue was interposed between non-overlapping suture lines. Vesico-psoas hitch was done in 29 patients of urterovaginal fistulae. All patients were continent following surgery. There were no urinary complaints in VVF patients and no UTI in UVF patients over a median follow-up of 3.2 years and 2.8 years respectively. Conclusion: Laparoscopic repair of UGF gives easy, quick access to the pelvic cavity. Interposition of tissue during VVF repair and vesico-psoas hitch during UVF repair form important steps to ensure successful repair.

  12. AN EFFICIENT DATA MINING METHOD TO FIND FREQUENT ITEM SETS IN LARGE DATABASE USING TR- FCTM

    Directory of Open Access Journals (Sweden)

    Saravanan Suba

    2016-01-01

    Full Text Available Mining association rules in large database is one of most popular data mining techniques for business decision makers. Discovering frequent item set is the core process in association rule mining. Numerous algorithms are available in the literature to find frequent patterns. Apriori and FP-tree are the most common methods for finding frequent items. Apriori finds significant frequent items using candidate generation with more number of data base scans. FP-tree uses two database scans to find significant frequent items without using candidate generation. This proposed TR-FCTM (Transaction Reduction- Frequency Count Table Method discovers significant frequent items by generating full candidates once to form frequency count table with one database scan. Experimental results of TR-FCTM shows that this algorithm outperforms than Apriori and FP-tree.

  13. Role of Rad54, Rad54b and Snm1 in DNA damage repair

    NARCIS (Netherlands)

    J. Wesoly (Joanna)

    2003-01-01

    textabstractThe aim of this thesis is to investigate the function of a number of genes involved in mammalian DNA damage repair, in particular in repair of DNA double-strand breaks (DSBs). Among a large number of different damages that can be introduced to DNA, DSBs are especially toxic. If left unre

  14. Role of Rad54, Rad54b and Snm1 in DNA damage repair

    NARCIS (Netherlands)

    J. Wesoly (Joanna)

    2003-01-01

    textabstractThe aim of this thesis is to investigate the function of a number of genes involved in mammalian DNA damage repair, in particular in repair of DNA double-strand breaks (DSBs). Among a large number of different damages that can be introduced to DNA, DSBs are especially toxic. If

  15. Investigating Item Exposure Control Methods in Computerized Adaptive Testing

    Science.gov (United States)

    Ozturk, Nagihan Boztunc; Dogan, Nuri

    2015-01-01

    This study aims to investigate the effects of item exposure control methods on measurement precision and on test security under various item selection methods and item pool characteristics. In this study, the Randomesque (with item group sizes of 5 and 10), Sympson-Hetter, and Fade-Away methods were used as item exposure control methods. Moreover,…

  16. 15 CFR 734.3 - Items subject to the EAR.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Items subject to the EAR. 734.3... EXPORT ADMINISTRATION REGULATIONS § 734.3 Items subject to the EAR. (a) Except for items excluded in paragraph (b) of this section, the following items are subject to the EAR: (1) All items in the...

  17. An Efficient Algorithm for Mining Maximal Frequent Item Sets

    Directory of Open Access Journals (Sweden)

    A. M.J.M.Z. Rahman

    2008-01-01

    Full Text Available Problem Statement: In today's life, the mining of frequent patterns is a basic problem in data mining applications. The algorithms which are used to generate these frequent patterns must perform efficiently. The objective was to propose an effective algorithm which generates frequent patterns in less time. Approach: We proposed an algorithm which was based on hashing technique and combines a vertical tidset representation of the database with effective pruning mechanisms. It removes all the non-maximal frequent item-sets to get exact set of MFI directly. It worked efficiently when the number of item-sets and tid-sets is more. Results: The performance of our algorithm had been compared with recently developed MAFIA algorithm and the results show how our algorithm gives better performance. Conclusions: Hence, the proposed algorithm performs effectively and generates frequent patterns faster.

  18. National trends for open and endovascular repair of aneurysms in Korea: 2004-2013.

    Science.gov (United States)

    Joh, Jin Hyun; Park, Yun-Young; Cho, Sung-Shin; Park, Ho-Chul

    2016-11-01

    The introduction of endovascular aneurysm repair has led to a dramatic decline in open aneurysm repair. The aim of this report was to evaluate Korean national trends for the treatment of aneurysms. A serial, cross-sectional study of time trends of patients who underwent aneurysm repair between 2004 and 2013 was conducted. Data from the Health Insurance Review and Assessment Service were used to evaluate the trends of aneurysm repair in the Korean population and to analyze the trends of open and endovascular aneurysm repair among Medicare beneficiaries. A linear-by-linear association was performed to determine alterations in the rates at which these aneurysm repair techniques were performed. A total of 32,130 patients underwent aneurysm repair between 2004 and 2013. The proportion of patients who underwent open repair decreased from 94.0% in 2004 to 54.9% in 2013; whereas the proportion of patients who underwent endovascular repair increased from 6.0% in 2004 to 45.1% in 2013. During the study period, the number of patients undergoing endovascular repair of aortic aneurysms significantly increased from 82 to 1,396 (relative risk, 16.17; 95% confidence interval: 12.94-20.21). Endovascular repair of abdominal aortic aneurysms (AAAs)overtook open repair between 2010 and 2011. The frequency of open aneurysm repair increased 1.2-fold, with an overall downward trend. The prevalence of endovascular repair markedly increased 15.3-fold. These findings indicated that, in Korea, the endovascular repair of AAAs overtook open repair as the most common technique between 2010 and 2011.

  19. Numbers, Please!

    Science.gov (United States)

    Thelin, John R.

    2013-01-01

    What topic would you choose if you had the luxury of writing forever? In this article, John Thelin provides his response: He would opt to write about the history of higher education in a way that relies on quantitative data. "Numbers, please!" is his research request in taking on a longitudinal study of colleges and universities over…

  20. Numbers, Please!

    Science.gov (United States)

    Thelin, John R.

    2013-01-01

    What topic would you choose if you had the luxury of writing forever? In this article, John Thelin provides his response: He would opt to write about the history of higher education in a way that relies on quantitative data. "Numbers, please!" is his research request in taking on a longitudinal study of colleges and universities over…

  1. Negative Numbers

    Science.gov (United States)

    Galbraith, Mary J.

    1974-01-01

    Examination of models for representing integers demonstrates that formal operational thought is required for establishing the operations on integers. Advocated is the use of many models for introducing negative numbers but, apart from addition, it is recommended that operations on integers be delayed until the formal operations stage. (JP)

  2. Number Sense in the Elementary School Mathematics Classroom.

    Science.gov (United States)

    McBride, John W.; Lamb, Charles E.

    1986-01-01

    The number sense program in Texas was developed to help motivate students to learn mathematics and to literally develop "number sense." A description of the program, a 70-item exercise (with answers), and teaching tips are provided. (JN)

  3. Perspective Application Directions of Fiber Optic Lasers in the Repair and Renewal Operations on the Linear Part of Main Gas Pipelines

    Directory of Open Access Journals (Sweden)

    Ivanov Vadim

    2016-01-01

    Full Text Available Large number of main pipelines requires today an immediate repair. Equipment producing entertainments supply the market with more and more new and advanced devices. However, their use does not always allow reducing the repair work period. That way it is appropriate to develop the alternative repair methods that allow reducing the labor intensity as well as the cost of repair and renewal operations. One of the promising areas is the laser technologies application in the repair process.

  4. An emotional functioning item bank of 24 items for computerized adaptive testing (CAT) was established

    DEFF Research Database (Denmark)

    Petersen, Morten Aa.; Gamper, Eva-Maria; Costantini, Anna

    2016-01-01

    OBJECTIVE: To improve measurement precision, the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group is developing an item bank for computerized adaptive testing (CAT) of emotional functioning (EF). The item bank will be within the conceptual framework...... of the widely used EORTC Quality of Life questionnaire (QLQ-C30). STUDY DESIGN AND SETTING: On the basis of literature search and evaluations by international samples of experts and cancer patients, 38 candidate items were developed. The psychometric properties of the items were evaluated in a large...... international sample of cancer patients. This included evaluations of dimensionality, item response theory (IRT) model fit, differential item functioning (DIF), and of measurement precision/statistical power. RESULTS: Responses were obtained from 1,023 cancer patients from four countries. The evaluations showed...

  5. Psychometric Changes on Item Difficulty Due to Item Review by Examinees

    Directory of Open Access Journals (Sweden)

    Elena C. Papanastasiou

    2015-01-01

    Full Text Available If good measurement depends in part on the estimation of accurate item characteristics, it is essential that test developers become aware of discrepancies that may exist on the item parameters before and after item review. The purpose of this study was to examine the answer changing patterns of students while taking paper-and-pencil multiple choice exams, and to examine how these changes affect the estimation of item difficulty parameters. The results of this study have shown that item review by examinees does produce some changes to the examinee ability estimates and to the item difficulty parameters. In addition, these effects are more pronounced in shorter tests than in longer tests. In turn, these small changes produce larger effects when estimating the changes in the information values of each student's test score.

  6. Origin bias of test items compromises the validity and fairness of curriculum comparisons.

    Science.gov (United States)

    Muijtjens, Arno M M; Schuwirth, Lambert W T; Cohen-Schotanus, Janke; van der Vleuten, Cees P M

    2007-12-01

    To determine whether items of progress tests used for inter-curriculum comparison favour students from the medical school where the items were produced (i.e. whether the origin bias of test items is a potential confounder in comparisons between curricula). We investigated scores of students from different schools on subtests consisting of progress test items constructed by authors from the different schools. In a cross-institutional collaboration between 3 medical schools, progress tests are jointly constructed and simultaneously administered to all students at the 3 schools. Test score data for 6 consecutive progress tests were investigated. Participants consisted of approximately 5000 undergraduate medical students from 3 medical schools. The main outcome measure was the difference between the scores on subtests of items constructed by authors from 2 of the collaborating schools (subtest difference score). The subtest difference scores showed that students obtained better results on items produced at their own schools. This effect was more pronounced in Years 2-5 of the curriculum than in Year 1, and diminished in Year 6. Progress test items were subject to origin bias. As a consequence, all participating schools should contribute equal numbers of test items if tests are to be used for valid and fair inter-curriculum comparisons.

  7. Repair of dental resin-based composites.

    Science.gov (United States)

    Baur, Veronika; Ilie, Nicoleta

    2013-03-01

    The study analyzed the reparability and compatibility of light-curing resin-based composites (RBCs) of the categories "microhybrid," "nanohybrid," and "packable." Six RBCs with different matrix and filler formulation--purely methacrylate-based composites (MBCs), ormocer-based composites (OBCs), and silorane-based composites (SBCs)--were used for the specimens. Every material was combined with itself and with the other five RBCs, resulting in a total of 36 combination groups (n = 20). The specimens were polymerized, aged for 8 weeks in distilled water at 37 °C, and then repaired by means of a repair kit. Shear bond strength and fracture mode were measured after aging of the specimens, undergoing storage for 24 h in distilled water at 37 °C followed by thermocycling (5,000 cycles, 5-55 °C) and an additional 4-week storage in distilled water at 37 °C. Data were statistically analyzed using ANOVA with TUKEY HSD post hoc test (α = 0.05). On average, the OBC Admira reached the highest value as a substrate material (30.41 MPa), and the SBC Filtek Silorane reached the lowest value (8.14 MPa). Filtek Silorane was identified as the repair material with the highest bond strength value (28.70 MPa), while a packable composite reached the lowest bond strength value (15.55 MPa). The analysis of the break modes showed that adhesive breaks are typical when strength is at its lowest (6.27 MPa). A large number of cohesive fractures are conspicuous when identical materials are used for repair, except Filtek Silorane (2 % cohesive fractures). The study demonstrated that the effect of the different materials on bond strength varies strongly, depending on whether the material is used as filling or as repair material. It is generally advisable but not compulsory to combine identical RBCs.

  8. Alternate item types: continuing the quest for authentic testing.

    Science.gov (United States)

    Wendt, Anne; Kenny, Lorraine E

    2009-03-01

    Many test developers suggest that multiple-choice items can be used to evaluate critical thinking if the items are focused on measuring higher order thinking ability. The literature supports the use of alternate item types to assess additional competencies, such as higher level cognitive processing and critical thinking, as well as ways to allow examinees to demonstrate their competencies differently. This research study surveyed nurses after taking a test composed of alternate item types paired with multiple-choice items. The participants were asked to provide opinions regarding the items and the item formats. Demographic information was asked. In addition, information was collected as the participants responded to the items. The results of this study reveal that the participants thought that, in general, the items were more authentic and allowed them to demonstrate their competence better than multiple-choice items did. Further investigation into the optimal blend of alternate items and multiple-choice items is needed.

  9. Laparoscopic Repair of Morgagni Hernia

    Directory of Open Access Journals (Sweden)

    ilker murat arer

    2015-03-01

    Full Text Available Morgagni hernia is a congenital herniation of abdominal contents into the thoracic cavity through a retrosternal diaphragmatic defect and make up about 1 % - 5 % of all types of congenital diaphragmatic hernias. Surgical repair of Morgagni hernias is usually indicated when patients are symptomatic and have a high risk of strangulation or incarceration of the contained viscera. 71-year-old male patient admitted to emergency department with a 2-day history of abdominal pain, vomiting and obstipation. Laparoscopic repair for Morgagni hernia was performed. Laparoscopic repair for Morgagni hernia with mesh repair is secure, satisfactory and easily performed. [Cukurova Med J 2015; 40(Suppl 1: 71-74

  10. Number names and number understanding

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    2014-01-01

    This paper concerns the results from the first year of a three-year research project involving the relationship between Danish number names and their corresponding digits in the canonical base 10 system. The project aims to develop a system to help the students’ understanding of the base 10 syste...

  11. Mammalian mismatch repair

    DEFF Research Database (Denmark)

    Pena Diaz, Javier; Jiricny, Josef

    2012-01-01

    A considerable surge of interest in the mismatch repair (MMR) system has been brought about by the discovery of a link between Lynch syndrome, an inherited predisposition to cancer of the colon and other organs, and malfunction of this key DNA metabolic pathway. This review focuses on recent...... advances in our understanding of the molecular mechanisms of canonical MMR, which improves replication fidelity by removing misincorporated nucleotides from the nascent DNA strand. We also discuss the involvement of MMR proteins in two other processes: trinucleotide repeat expansion and antibody maturation...

  12. Algorithms to reveal the representation of characters, integers, and floating-point numbers. [NCHAR, LBBIT, REP, CMPR, FORM, ICONV, IMAGE, NBLANK, and ITEM in FORTRAN IV for CDC 6400, DEC PDP-10, IBM 360/370, Honeywell 6050, and Univac 1108

    Energy Technology Data Exchange (ETDEWEB)

    George, J.E.

    1975-09-01

    Three algorithms are presented as a set of Standard Fortran subroutines which compute the number of characters representable in a single storage unit, the number of bits representing a character, and the type of integer representation. This information provides for the determination of a lower bound for the floating-point exponent length. The method used for the computations is rarely discussed in the literature of programing techniques and is applicable to other languages. The assumptions of the algorithm and the accuracy of the results are discussed. 1 table.

  13. Identification of novel DNA repair proteins via primary sequence, secondary structure, and homology

    Directory of Open Access Journals (Sweden)

    Akutsu Tatsuya

    2009-01-01

    Full Text Available Abstract Background DNA repair is the general term for the collection of critical mechanisms which repair many forms of DNA damage such as methylation or ionizing radiation. DNA repair has mainly been studied in experimental and clinical situations, and relatively few information-based approaches to new extracting DNA repair knowledge exist. As a first step, automatic detection of DNA repair proteins in genomes via informatics techniques is desirable; however, there are many forms of DNA repair and it is not a straightforward process to identify and classify repair proteins with a single optimal method. We perform a study of the ability of homology and machine learning-based methods to identify and classify DNA repair proteins, as well as scan vertebrate genomes for the presence of novel repair proteins. Combinations of primary sequence polypeptide frequency, secondary structure, and homology information are used as feature information for input to a Support Vector Machine (SVM. Results We identify that SVM techniques are capable of identifying portions of DNA repair protein datasets without admitting false positives; at low levels of false positive tolerance, homology can also identify and classify proteins with good performance. Secondary structure information provides improved performance compared to using primary structure alone. Furthermore, we observe that machine learning methods incorporating homology information perform best when data is filtered by some clustering technique. Analysis by applying these methodologies to the scanning of multiple vertebrate genomes confirms a positive correlation between the size of a genome and the number of DNA repair protein transcripts it is likely to contain, and simultaneously suggests that all organisms have a non-zero minimum number of repair genes. In addition, the scan result clusters several organisms' repair abilities in an evolutionarily consistent fashion. Analysis also identifies several

  14. DNA replication, repair, and repair tests. [Rat; human leukocytes

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, B.

    1980-09-01

    The rate of inhibition and recovery of DNA synthesis can be used in a rapid assay system to detect genotoxic potentials of chemicals. Also, the observation that an agent stimulates DNA repair in a test system indicates its ability to cause damage in DNA. Different experimental approaches to the study of repair synthesis are discussed.

  15. Emergent cardiopulmonary bypass during pectus excavatum repair

    Directory of Open Access Journals (Sweden)

    Ryan Craner

    2013-01-01

    Full Text Available Pectus excavatum is a chest wall deformity that produces significant cardiopulmonary disability and is typically seen in younger patients. Minimally invasive repair of pectus excavatum or Nuss procedure has become a widely accepted technique for adult and pediatric patients. Although it is carried out through a thoracoscopic approach, the procedure is associated with a number of potential intraoperative and post-operative complications. We present a case of cardiac perforation requiring emergent cardiopulmonary bypass in a 29-year-old male with Marfan syndrome and previous mitral valve repair undergoing a Nuss procedure for pectus excavatum. This case illustrates the importance of vigilance and preparation by the surgeons, anesthesia providers as well as the institution to be prepared with resources to handle the possible complications. This includes available cardiac surgical backup, perfusionist support and adequate blood product availability.

  16. The Effects of Continuous and Interrupted Episiotomy Repair on Pain Severity and Rate of Perineal Repair: A Controlled Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Shirin Hasanpoor

    2012-08-01

    Full Text Available Introduction: Perineal pain is the most common complaint after episiotomy. It imposes extra pressure on mothers who attempt to adapt to their new conditions. Therefore, the present study was performed to compare pain severity and perineal repair in two episiot-omy repair methods. Methods: In this clinical trial, 100 primiparous women who re-ferred to hospitals of Tabriz (Iran for delivery were randomly allocated into two groups of 50 to undergo either continuous or interrupted episiotomy repair. A visual analogue scale (VAS was used to evaluate pain severity 12-18 hours after episiotomy repair and also 10 days after delivery. Perineal repair rate was also assessed using the REEDA (redness, edema, ecchymosis, discharge, and approximation scoring scale. The obtained data was analyzed in SPSS15. Results: Statistical tests did not show significant differ-ences between the 2 groups in pain severity variations or REEDA scores at 12-18 hours and the 10th day after delivery. However, the mean required time for repair and the num-ber of used threads were significantly lower in the continuous repair group (p < 0.001. Conclusion: The results of this study showed that pain severity and episiotomy repair rate were similar in the two methods. Nevertheless, shorter time of repair and fewer threads were required using the continuous repair method. Therefore, this method would provide better services for mothers and reduce the required time, energy, and costs.

  17. Biologics for tendon repair.

    Science.gov (United States)

    Docheva, Denitsa; Müller, Sebastian A; Majewski, Martin; Evans, Christopher H

    2015-04-01

    Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly because these injuries often respond poorly to treatment and require prolonged rehabilitation. Therapeutic options used to repair ruptured tendons have consisted of suture, autografts, allografts, and synthetic prostheses. To date, none of these alternatives has provided a successful long-term solution, and often the restored tendons do not recover their complete strength and functionality. Unfortunately, our understanding of tendon biology lags far behind that of other musculoskeletal tissues, thus impeding the development of new treatment options for tendon conditions. Hence, in this review, after introducing the clinical significance of tendon diseases and the present understanding of tendon biology, we describe and critically assess the current strategies for enhancing tendon repair by biological means. These consist mainly of applying growth factors, stem cells, natural biomaterials and genes, alone or in combination, to the site of tendon damage. A deeper understanding of how tendon tissue and cells operate, combined with practical applications of modern molecular and cellular tools could provide the long awaited breakthrough in designing effective tendon-specific therapeutics and overall improvement of tendon disease management.

  18. Kvitebjoern gas pipeline repair - baptism of remote pipeline repair system

    Energy Technology Data Exchange (ETDEWEB)

    Gjertveit, Erling

    2010-07-01

    On the 1st of November 2007, severe anchor damage was discovered on the 30 inch Kvitebjoern gas export pipeline. The damage constituted a localised dent and a 17deg buckle, but no leakage. Statoil has invested in building an effective repair contingency structure for the large pipeline network on the Norwegian Continental shelf, with particular focus on the large gas export pipelines. The repair method for the Kvitebjoern pipeline was remotely operated using two Morgrip couplings and a spool. The installation used the purpose built Pipeline Repair System stored at Killingoey and couplings produced and tested back in 2005. This presentation will cover the initial damage investigations, the temporary operational phase, the repair preparations, the actual repair and lessons learned. (Author)

  19. Measuring response styles in Likert items.

    Science.gov (United States)

    Böckenholt, Ulf

    2017-03-01

    The recently proposed class of item response tree models provides a flexible framework for modeling multiple response processes. This feature is particularly attractive for understanding how response styles may affect answers to attitudinal questions. Facilitating the disassociation of response styles and attitudinal traits, item response tree models can provide powerful process tests of how different response formats may affect the measurement of substantive traits. In an empirical study, 3 response formats were used to measure the 2-dimensional Personal Need for Structure traits. Different item response tree models are proposed to capture the response styles for each of the response formats. These models show that the response formats give rise to similar trait measures but different response-style effects. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  20. Physics Items and Student's Performance at Enem

    CERN Document Server

    Gonçalves, Wanderley P

    2013-01-01

    The Brazilian National Assessment of Secondary Education (ENEM, Exame Nacional do Ensino M\\'edio) has changed in 2009: from a self-assessment of competences at the end of high school to an assessment that allows access to college and student financing. From a single general exam, now there are tests in four areas: Mathematics, Language, Natural Sciences and Social Sciences. A new Reference Matrix is build with components as cognitive domains, competencies, skills and knowledge objects; also, the methodological framework has changed, using now Item Response Theory to provide scores and allowing longitudinal comparison of results from different years, providing conditions for monitoring high school quality in Brazil. We present a study on the issues discussed in Natural Science Test of ENEM over the years 2009, 2010 and 2011. Qualitative variables are proposed to characterize the items, and data from students' responses in Physics items were analysed. The qualitative analysis reveals the characteristics of the ...

  1. Validation of Physics Standardized Test Items

    Science.gov (United States)

    Marshall, Jill

    2008-10-01

    The Texas Physics Assessment Team (TPAT) examined the Texas Assessment of Knowledge and Skills (TAKS) to determine whether it is a valid indicator of physics preparation for future course work and employment, and of the knowledge and skills needed to act as an informed citizen in a technological society. We categorized science items from the 2003 and 2004 10th and 11th grade TAKS by content area(s) covered, knowledge and skills required to select the correct answer, and overall quality. We also analyzed a 5000 student sample of item-level results from the 2004 11th grade exam using standard statistical methods employed by test developers (factor analysis and Item Response Theory). Triangulation of our results revealed strengths and weaknesses of the different methods of analysis. The TAKS was found to be only weakly indicative of physics preparation and we make recommendations for increasing the validity of standardized physics testing..

  2. Molecular mechanisms of DNA repair inhibition by caffeine

    Energy Technology Data Exchange (ETDEWEB)

    Selby, C.P.; Sancar, A. (Univ. of North Carolina School of Medicine, Chapel Hill (USA))

    1990-05-01

    Caffeine potentiates the mutagenic and lethal effects of genotoxic agents. It is thought that this is due, at least in some organisms, to inhibition of DNA repair. However, direct evidence for inhibition of repair enzymes has been lacking. Using purified Escherichia coli DNA photolyase and (A)BC excinuclease, we show that the drug inhibits photoreactivation and nucleotide excision repair by two different mechanisms. Caffeine inhibits photoreactivation by interfering with the specific binding of photolyase to damaged DNA, and it inhibits nucleotide excision repair by promoting nonspecific binding of the damage-recognition subunit, UvrA, of (A)BC excinuclease. A number of other intercalators, including acriflavin and ethidium bromide, appear to inhibit the excinuclease by a similar mechanism--that is, by trapping the UvrA subunit in nonproductive complexes on undamaged DNA.

  3. Air Force Officer Qualifying Test Form T: Initial Item-, Test-, Factor-,and Composite-Level Analyses

    Science.gov (United States)

    2016-12-01

    AFRL-RH-WP-TR-2016-0093 AIR FORCE OFFICER QUALIFYING TEST FORM T: INITIAL ITEM-, TEST -, FACTOR-, AND COMPOSITE-LEVEL ANALYSES...July 2016 – 28 Nov 2016 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER FA8650-11-C-6158 Air Force Officer Qualifying Test Form T...Initial Item-, Test -, Factor-, and Composite-Level Analyses 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62202F 6. AUTHOR(S) 5d. PROJECT

  4. Developing Multidimensional Likert Scales Using Item Factor Analysis: The Case of Four-Point Items

    Science.gov (United States)

    Asún, Rodrigo A.; Rdz-Navarro, Karina; Alvarado, Jesús M.

    2016-01-01

    This study compares the performance of two approaches in analysing four-point Likert rating scales with a factorial model: the classical factor analysis (FA) and the item factor analysis (IFA). For FA, maximum likelihood and weighted least squares estimations using Pearson correlation matrices among items are compared. For IFA, diagonally weighted…

  5. Evaluating Item Discrimination Power of WHOQOL-BREF from an Item Response Model Perspectives

    Science.gov (United States)

    Lin, Ting Hsiang; Yao, Grace

    2009-01-01

    Quality of life (QOL) has become an important component of health. By using the methodology of psychometric theory, we examine the item properties of the WHOQOL-BRIEF. Samejima's graded response model with natural metrics of the logistic response function was fitted. The results showed items with negative natures were less discriminating. Items…

  6. Application of Unidimensional Item Response Models to Tests with Items Sensitive to Secondary Dimensions

    Science.gov (United States)

    Zhang, Bo

    2008-01-01

    In this research, the author addresses whether the application of unidimensional item response models provides valid interpretation of test results when administering items sensitive to multiple latent dimensions. Overall, the present study found that unidimensional models are quite robust to the violation of the unidimensionality assumption due…

  7. Are Inferential Reading Items More Susceptible to Cultural Bias than Literal Reading Items?

    Science.gov (United States)

    Banks, Kathleen

    2012-01-01

    The purpose of this article is to illustrate a seven-step process for determining whether inferential reading items were more susceptible to cultural bias than literal reading items. The seven-step process was demonstrated using multiple-choice data from the reading portion of a reading/language arts test for fifth and seventh grade Hispanic,…

  8. Modeling Local Item Dependence in Cloze and Reading Comprehension Test Items Using Testlet Response Theory

    Science.gov (United States)

    Baghaei, Purya; Ravand, Hamdollah

    2016-01-01

    In this study the magnitudes of local dependence generated by cloze test items and reading comprehension items were compared and their impact on parameter estimates and test precision was investigated. An advanced English as a foreign language reading comprehension test containing three reading passages and a cloze test was analyzed with a…

  9. Item Structure as a Determinant of Item Difficulty in Verbal Analogies

    Science.gov (United States)

    Ace, Merle C.; Dawis, Rene V.

    1973-01-01

    Because no previous study was found in which both blank position in the item stem and positional placement of the correct response were studied simultaneously, it was decided to investigate the influence of these two factors, alone and in combination, on the difficulty level of verbal analogy items. (Authors)

  10. Secondary Item Procurement Lead Time Study.

    Science.gov (United States)

    1984-03-01

    NONEhhhhhh % I - 15 III& 1-- -NAION&°I° oI Ai OF .° NAIU REUONF TEST CANA -~~ 7 .. SECONDARY ITEM PROCUREMENT LEAD TIME STUDY __ LOGISTICS SYSTEMS...ASSISTANT SECRETARY OF THE AIR FORCE (RD&L) DIRECTOR, DEFENSE LOGISTICS AGENCY SUBJECT: Secondary Item Procurement Lead Time Study A recent report by the...determination of procurement lead time. A plan for the study is enclosed. In order to achieve the objectives of the procurement lead time study as well as the

  11. MULTI-ITEM FAIR EXCHANGE SCHEME

    Institute of Scientific and Technical Information of China (English)

    Zheng Dong; Chen Kefei

    2002-01-01

    As more business is conduced over the Internet, the fair exchange problem assumes increasing importance. However, the problem of multi-party fair exchange has not been studied as widely as the more fundamental problem of 2-party fair exchange. Recently, Franklin and Tsudik proposed two protocols for n-party multi-item exchange on FC'98, SUCEX-1 and SUCES-2. This paper first gives an attack on the proposed protocol SUCEX-1, then presents two protocols for multi-item exchange, one is an improved protocol of SUCEX-1, another is the extension of protocol SUCEX-2.

  12. MULTI—ITEM FAIR EXCHANGE SCHEME

    Institute of Scientific and Technical Information of China (English)

    ZhengDong; ChenKefei

    2002-01-01

    As more ubsiness is conduced over the Internet,the fair exchange problem assumes increasing importance,However,the problem of multi-party fair exchange has not been studied as widely as the more fundamental problem of 2-party fair exchange,Recently,Franklin and Tsudik proposed two protocols for n-parth multi-item exchange on FC'98,SUCEX-1 and SUCES-2,This paper first gives an attack on the proposed protocol SUCEX-1,then presents two protocols for multi-item exchange,one is an improoved protocol of SUCEX-1,another is the extension of protocol SUCEX-2.

  13. Comparison on Computed Tomography using industrial items

    DEFF Research Database (Denmark)

    Angel, Jais Andreas Breusch; De Chiffre, Leonardo

    2014-01-01

    In a comparison involving 27 laboratories from 8 countries, measurements on two common industrial items, a polymer part and a metal part, were carried out using X-ray Computed Tomography. All items were measured using coordinate measuring machines before and after circulation, with reference...... measurement uncertainties in the range 1.5–5.5 μm, showing a good stability over the 6 months of the circulation. The comparison has shown that CT measurements on the industrial parts used lie in the range 6–53 μm, with maximum values up to 158 μm....

  14. Handbook of adhesive bonded structural repair

    CERN Document Server

    Wegman, Raymond F

    1992-01-01

    Provides repair methods for adhesive bonded and composite structures; identifies suitable materials and equipment for repairs; describes damage evaluation criteria and techniques, and methods of inspection before and after repair.

  15. Real-time learning of predictive recognition categories that chunk sequences of items stored in working memory

    Directory of Open Access Journals (Sweden)

    Stephen eGrossberg

    2014-10-01

    Full Text Available How are sequences of events that are temporarily stored in a cognitive working memory unitized, or chunked, through learning? Such sequential learning is needed by the brain in order to enable language, spatial understanding, and motor skills to develop. In particular, how does the brain learn categories, or list chunks, that become selectively tuned to different temporal sequences of items in lists of variable length as they are stored in working memory, and how does this learning process occur in real time? The present article introduces a neural model that simulates learning of such list chunks. In this model, sequences of items are temporarily stored in an Item-and-Order, or competitive queuing, working memory before learning categorizes them using a categorization network, called a Masking Field, which is a self-similar, multiple-scale, recurrent on-center off-surround network that can weigh the evidence for variable-length sequences of items as they are stored in the working memory through time. A Masking Field hereby activates the learned list chunks that represent the most predictive item groupings at any time, while suppressing less predictive chunks. In a network with a given number of input items, all possible ordered sets of these item sequences, up to a fixed length, can be learned with unsupervised or supervised learning. The self-similar multiple-scale properties of Masking Fields interacting with an Item-and-Order working memory provide a natural explanation of George Miller's Magical Number Seven and Nelson Cowan's Magical Number Four. The article explains why linguistic, spatial, and action event sequences may all be stored by Item-and-Order working memories that obey similar design principles, and thus how the current results may apply across modalities. Item-and-Order properties may readily be extended to Item-Order-Rank working memories in which the same item can be stored in multiple list positions, or ranks, as in the list

  16. Murdock free recall data: The initial recall search identifies the context by the location of the least remembered item and produces only better remembered items in proportion to the total recall difference.

    OpenAIRE

    Tarnow, Dr Eugen

    2009-01-01

    The curious free recall data of Murdock (1962) shows an additional surprise that seems to have gone undetected until now: the probability of guessing an item in the initial recall is not identical to the overall free recall curve. Initial recall of an item is well correlated with the total recall of that item using a straight line but with an unexpected offset. The offset varies with the presentation rate and the total number of list items but in each case it is the same as the total recall ...

  17. What proportion of prescription items dispensed in community pharmacies are eligible for the New Medicine Service?

    Science.gov (United States)

    Wells, Katharine M; Boyd, Matthew J; Thornley, Tracey; Boardman, Helen F

    2014-03-07

    The payment structure for the New Medicine Service (NMS) in England is based on the assumption that 0.5% of prescription items dispensed in community pharmacies are eligible for the service. This assumption is based on a theoretical calculation. This study aimed to find out the actual proportion of prescription items eligible for the NMS dispensed in community pharmacies in order to compare this with the theoretical assumption. The study also aimed to investigate whether the proportion of prescription items eligible for the NMS is affected by pharmacies' proximity to GP practices. The study collected data from eight pharmacies in Nottingham belonging to the same large chain of pharmacies. Pharmacies were grouped by distance from the nearest GP practice and sampled to reflect the distribution by distance of all pharmacies in Nottingham. Data on one thousand consecutive prescription items were collected from each pharmacy and the number of NMS eligible items recorded. All NHS prescriptions were included in the sample. Data were analysed and proportions calculated with 95% confidence intervals used to compare the study results against the theoretical figure of 0.5% of prescription items being eligible for the NMS. A total of 8005 prescription items were collected (a minimum of 1000 items per pharmacy) of which 17 items were eligible to receive the service. The study found that 0.25% (95% confidence intervals: 0.14% to 0.36%) of prescription items were eligible for the NMS which differs significantly from the theoretical assumption of 0.5%. The opportunity rate for the service was lower, 0.21% (95% confidence intervals: 0.10% to 0.32%) of items, as some items eligible for the NMS did not translate into opportunities to offer the service. Of all the prescription items collected in the pharmacies, 28% were collected by patient representatives. The results of this study show that the proportion of items eligible for the NMS dispensed in community pharmacies is lower than

  18. Clamp wins pipe repair prize

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2001-04-01

    This paper describes the permanent pipeline repair system, developed by Tekmar, which is powered by seawater hydraulics and is easily installed and tested by any workclass remotely operated vehicle (rov). Details are given of the two main components of the system, namely, the diverless high pressure split repair clamp and the rov-operated tool to install it.

  19. The journey of DNA repair

    OpenAIRE

    Saini, Natalie

    2015-01-01

    21 years ago, the DNA Repair Enzyme was declared “Molecule of the Year”. Today, we are celebrating another “year of repair”, with the 2015 Nobel Prize in Chemistry being awarded to Aziz Sancar, Tomas Lindahl and Paul Modrich for their collective work on the different DNA repair pathways.

  20. Nucleotide excision repair in yeast

    NARCIS (Netherlands)

    Eijk, Patrick van

    2012-01-01

    Nucleotide Excision Repair (NER) is a conserved DNA repair pathway capable of removing a broad spectrum of DNA damage. In human cells a defect in NER leads to the disorder Xeroderma pigmentosum (XP). The yeast Saccharomyces cerevisiae is an excellent model organism to study the mechanism of NER. The

  1. Economic order quantity model for deteriorating items with imperfect quality and permissible delay on payment

    Directory of Open Access Journals (Sweden)

    Chandra K. Jaggi

    2011-04-01

    Full Text Available In the classical inventory models, most of the time the issue of quality has not been considered. However, in realistic environment, it can be observed that there may be some defective items in an ordered lot, because of these defective items retailer incurs additional cost due to rejection, repair and refund etc. Thus, inspection/screening of lot becomes indispensible in most of the organizations. Moreover, it plays a very essential role when items are of deteriorating in nature. Further, it is generally assumed that payment will be made to the supplier for the goods immediately after receiving the consignment. Whereas, in practice, supplier does offers a certain fixed period to the retailer for settling the account. During this period, supplier charges no interest, but beyond this period interest is being charged as has been agreed upon. On the other hand, retailer can earn interest on the revenue generated during this period. Keeping this scenario in mind, an attempt has been made to formulate an inventory model for deteriorating items with imperfect quality under permissible delay in payments. Results have been validated with the help of a numerical example using Matlab7.0.1. Comprehensive sensitivity analysis has also been presented.

  2. A production inventory model with deteriorating items and shortages

    Directory of Open Access Journals (Sweden)

    Samanta G.P.

    2004-01-01

    Full Text Available A continuous production control inventory model for deteriorating items with shortages is developed. A number of structural properties of the inventory system are studied analytically. The formulae for the optimal average system cost, stock level, backlog level and production cycle time are derived when the deterioration rate is very small. Numerical examples are taken to illustrate the procedure of finding the optimal total inventory cost, stock level, backlog level and production cycle time. Sensitivity analysis is carried out to demonstrate the effects of changing parameter values on the optimal solution of the system.

  3. A Fully Contained Resin Infusion Process for Fiber-Reinforced Polymer Composite Fabrication and Repair

    Science.gov (United States)

    2013-01-01

    Assisted Resin Transfer Molding ( VARTM ) process is applicable for fiber-reinforced polymer (FRP) composite fabrication and repair. However, VARTM in...scenario is a fully enclosed VARTM system that limits the need for laboratory or manufacturing equipment. The Bladder-Bag VARTM (BBVARTM) technique...composite fabrication, VARTM , composite repair, in-field repair 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18. NUMBER

  4. Generalizability and Dependability of a Multi-Item Direct Behavior Rating Scale in a Kindergarten Classroom Setting

    Science.gov (United States)

    Wickerd, Garry; Hulac, David

    2017-01-01

    Accurate and rapid identification of students displaying behavioral problems requires instrumentation that is user friendly and reliable. The purpose of the study was to evaluate a multi-item direct behavior rating scale called the Direct Behavior Rating-Multiple Item Scale (DBR-MIS) for disruptive behavior to determine the number of…

  5. Rethinking transcription coupled DNA repair.

    Science.gov (United States)

    Kamarthapu, Venu; Nudler, Evgeny

    2015-04-01

    Nucleotide excision repair (NER) is an evolutionarily conserved, multistep process that can detect a wide variety of DNA lesions. Transcription coupled repair (TCR) is a subpathway of NER that repairs the transcribed DNA strand faster than the rest of the genome. RNA polymerase (RNAP) stalled at DNA lesions mediates the recruitment of NER enzymes to the damage site. In this review we focus on a newly identified bacterial TCR pathway in which the NER enzyme UvrD, in conjunction with NusA, plays a major role in initiating the repair process. We discuss the tradeoff between the new and conventional models of TCR, how and when each pathway operates to repair DNA damage, and the necessity of pervasive transcription in maintaining genome integrity. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. AVOID BECOMING A VICTIM OF COUNTERFEIT ITEMS

    Energy Technology Data Exchange (ETDEWEB)

    WARRINER RD

    2011-07-13

    In today's globalized economy, we cannot live without imported products. Most people do not realize how thin the safety net of regulation and inspection really is. Less than three percent of imported products receive any form of government inspection prior to sale. Avoid flea markets, street vendors and deep discount stores. The sellers of counterfeit wares know where to market their products. They look for individuals who are hungry for a brand name item but do not want to pay a brand name price for it. The internet provides anonymity to the sellers of counterfeit products. Unlike Europe, U.S. law does not hold internet-marketing organizations, responsible for the quality of the products sold on their websites. These organizations will remove an individual vendor when a sufficient number of complaints are lodged, but they will not take responsibility for the counterfeit products you may have purchased. EBay has a number of counterfeit product guides to help you avoid being a victim of the sellers of these products. Ten percent of all medications taken worldwide are counterfeit. If you do buy medications on-line, be sure that the National Association of Boards of Pharmacy Verified Internet Pharmacy Practice Sites (VIPPS) recommends the pharmacy you choose to use. Inspect all medication purchases and report any change in color, shape, imprinting or odor to your pharmacist. If you take generic medications these attributes may change from one manufacturer to another. Your pharmacist should inform you of any changes when you refill your prescription. If they do not, get clarification prior to taking the medication. Please note that the Federal Drug Administration (FDA) does not regulate supplements. The FDA only steps in when a specific supplement proves to cause physical harm or contains a regulated ingredient. Due to counterfeiting, Underwriters Laboratories (UL) changed their label design three times since 1996. The new gold label should be attached to the cord

  7. Principles and procedures of considering item sequence effects in the development of calibrated item pools: Conceptual analysis and empirical illustration

    Directory of Open Access Journals (Sweden)

    Safir Yousfi

    2012-12-01

    Full Text Available Item responses can be context-sensitive. Consequently, composing test forms flexibly from a calibrated item pool requires considering potential context effects. This paper focuses on context effects that are related to the item sequence. It is argued that sequence effects are not necessarily a violation of item response theory but that item response theory offers a powerful tool to analyze them. If sequence effects are substantial, test forms cannot be composed flexibly on the basis of a calibrated item pool, which precludes applications like computerized adaptive testing. In contrast, minor sequence effects do not thwart applications of calibrated item pools. Strategies to minimize the detrimental impact of sequence effects on item parameters are discussed and integrated into a nomenclature that addresses the major features of item calibration designs. An example of an item calibration design demonstrates how this nomenclature can guide the process of developing a calibrated item pool.

  8. Wound repair in Pocillopora

    Science.gov (United States)

    Rodríguez-Villalobos, Jenny Carolina; Work, Thierry M.; Calderon-Aguileraa, Luis Eduardo

    2016-01-01

    Corals routinely lose tissue due to causes ranging from predation to disease. Tissue healing and regeneration are fundamental to the normal functioning of corals, yet we know little about this process. We described the microscopic morphology of wound repair in Pocillopora damicornis. Tissue was removed by airbrushing fragments from three healthy colonies, and these were monitored daily at the gross and microscopic level for 40 days. Grossly, corals healed by Day 30, but repigmentation was not evident at the end of the study (40 d). On histology, from Day 8 onwards, tissues at the lesion site were microscopically indistinguishable from adjacent normal tissues with evidence of zooxanthellae in gastrodermis. Inflammation was not evident. P. damicornis manifested a unique mode of regeneration involving projections of cell-covered mesoglea from the surface body wall that anastomosed to form gastrovascular canals.

  9. Groin hernia repair

    DEFF Research Database (Denmark)

    Kehlet, Henrik; Aasvang, Eske

    2005-01-01

    The choice of anesthesia for groin hernia repair is between general, regional (epidural or spinal), and local anesthesia. Existing data from large consecutive patient series and randomized studies have shown local anesthesia to be the method of choice because it can be performed by the surgeon......, does not necessarily require an attending anesthesiologist, translates into the shortest recovery (bypassing the postanesthesia care unit), has the lowest cost, and has the lowest postoperative morbidity regarding risk of urinary retention. Spinal anesthesia has no documented benefits for this small...... scientific data to support the choice of anesthesia, large epidemiologic and nationwide information from databases show an undesirable high (about 10-20%) use of spinal anesthesia and low (about 10%) use of local infiltration anesthesia. Surgeons and anesthesiologists should therefore adjust their anesthesia...

  10. 10 CFR 74.55 - Item monitoring.

    Science.gov (United States)

    2010-01-01

    ..., except for reactor components measuring at least one meter in length and weighing in excess of 30... 10 Energy 2 2010-01-01 2010-01-01 false Item monitoring. 74.55 Section 74.55 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) MATERIAL CONTROL AND ACCOUNTING OF SPECIAL NUCLEAR MATERIAL...

  11. The Fantastic Four of Mathematics Assessment Items

    Science.gov (United States)

    Greenlees, Jane

    2011-01-01

    In this article, the author makes reference to four comic book characters to make the point that together they are a formidable team, but on their own they are vulnerable. She examines the four components of mathematics assessment items and the need for implicit instruction within the classroom for student success. Just like the "Fantastic Four"…

  12. 47 CFR 65.820 - Included items.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Included items. 65.820 Section 65.820 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERSTATE RATE...) Cash working capital. The average amount of investor-supplied capital needed to provide funds for...

  13. Algorithmic test design using classical item parameters

    NARCIS (Netherlands)

    van der Linden, Willem J.; Adema, Jos J.

    1988-01-01

    Two optimalization models for the construction of tests with a maximal value of coefficient alpha are given. Both models have a linear form and can be solved by using a branch-and-bound algorithm. The first model assumes an item bank calibrated under the Rasch model and can be used, for instance, wh

  14. Estimating the Importance of Differential Item Functioning.

    Science.gov (United States)

    Rudas, Tamas; Zwick, Rebecca

    1997-01-01

    The mixture index of fit (T. Rudas et al, 1994) is used to estimate the fraction of a population for which differential item functioning (DIF) occurs, and this approach is compared to the Mantel Haenszel test of DIF. The proposed noniterative procedure provides information about data portions contributing to DIF. (SLD)

  15. Item Feature Effects in Evolution Assessment

    Science.gov (United States)

    Nehm, Ross H.; Ha, Minsu

    2011-01-01

    Despite concerted efforts by science educators to understand patterns of evolutionary reasoning in science students and teachers, the vast majority of evolution education studies have failed to carefully consider or control for item feature effects in knowledge measurement. Our study explores whether robust contextualization patterns emerge within…

  16. Bayesian item selection criteria for adaptive testing

    NARCIS (Netherlands)

    Linden, van der Wim J.

    1996-01-01

    R.J. Owen (1975) proposed an approximate empirical Bayes procedure for item selection in adaptive testing. The procedure replaces the true posterior by a normal approximation with closed-form expressions for its first two moments. This approximation was necessary to minimize the computational comple

  17. Bayesian item selection criteria for adaptive testing

    NARCIS (Netherlands)

    van der Linden, Willem J.

    1996-01-01

    R.J. Owen (1975) proposed an approximate empirical Bayes procedure for item selection in adaptive testing. The procedure replaces the true posterior by a normal approximation with closed-form expressions for its first two moments. This approximation was necessary to minimize the computational comple

  18. Estimating the Importance of Differential Item Functioning.

    Science.gov (United States)

    Rudas, Tamas; Zwick, Rebecca

    1997-01-01

    The mixture index of fit (T. Rudas et al, 1994) is used to estimate the fraction of a population for which differential item functioning (DIF) occurs, and this approach is compared to the Mantel Haenszel test of DIF. The proposed noniterative procedure provides information about data portions contributing to DIF. (SLD)

  19. Item Feature Effects in Evolution Assessment

    Science.gov (United States)

    Nehm, Ross H.; Ha, Minsu

    2011-01-01

    Despite concerted efforts by science educators to understand patterns of evolutionary reasoning in science students and teachers, the vast majority of evolution education studies have failed to carefully consider or control for item feature effects in knowledge measurement. Our study explores whether robust contextualization patterns emerge within…

  20. Optimal inspection and Repair Strategies for Structural Systems

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Faber, Michael Havbro

    1992-01-01

    A model for reliability-based repair and maintenance strategies of structural systems is described. The total expected costs in the lifetime of the structure are minimized with the number of inspections, the number and positions of the inspected points, the inspection efforts, the repair criteria...... to be inspected and to select the location of the points to be inspected. It is shown how information obtained through inspections and through the periods of normal operating of the structure can be used to update the inspection and maintenance planning. Finally, a small example is given illustrating...

  1. A note on using alpha and stratified alpha to estimate the reliability of a test composed of item parcels.

    Science.gov (United States)

    Rae, Gordon

    2008-11-01

    Several authors have suggested that prior to conducting a confirmatory factor analysis it may be useful to group items into a smaller number of item 'parcels' or 'testlets'. The present paper mathematically shows that coefficient alpha based on these parcel scores will only exceed alpha based on the entire set of items if W, the ratio of the average covariance of items between parcels to the average covariance of items within parcels, is greater than unity. If W is less than unity, however, and errors of measurement are uncorrelated, then stratified alpha will be a better lower bound to the reliability of a measure than the other two coefficients. Stratified alpha are also equal to the true reliability of a test when items within parcels are essentially tau-equivalent if one assumes that errors of measurement are not correlated.

  2. Examining the structure of emotional intelligence at the item level: new perspectives, new conclusions.

    Science.gov (United States)

    Maul, Andrew

    2012-01-01

    Despite twenty years of research, many unknowns remain regarding the Mayer-Salovey (e.g., 1997) model of emotional intelligence (EI) and the validity of tests that have been designed to measure it. Evidence relevant to the internal structure of EI has come mainly from factor-analytic studies of the MSCEIT and the MEIS, utilising parcelled task scores rather than individual test items. This approach has several deficiencies: in addition to the loss of item-level information, it results in an insufficient number of observed variables per factor and an inability to separate structural sources of local item dependence (i.e., method variance) from construct-related variance. The present study (N=707) employed multidimensional item response modelling to investigate the dimensional structure of the MSCEIT, at the item level, for the first time. It is shown that item format and the specific choice of task explain far more of the variance in response patterns than does the hypothesised dimensional structure of EI, to the point that there is no empirical reason to prefer a higher-dimensional model of EI over a unidimensional model. It is argued that the advantage of an item-level perspective can be fundamental, rather than merely incremental.

  3. Mixture randomized item-response modeling: a smoking behavior validation study.

    Science.gov (United States)

    Fox, J-P; Avetisyan, M; van der Palen, J

    2013-11-30

    Misleading response behavior is expected in medical settings where incriminating behavior is negatively related to the recovery from a disease. In the present study, lung patients feel social and professional pressure concerning smoking and experience questions about smoking behavior as sensitive and tend to conceal embarrassing or threatening information. The randomized item-response survey method is expected to improve the accuracy of self-reports as individual item responses are masked and only randomized item responses are observed. We explored the validation of the randomized item-response technique in a unique experimental study. Therefore, we administered a new multi-item measure assessing smoking behavior by using a treatment-control design (randomized response (RR) or direct questioning). After the questionnaire, we administered a breath test by using a carbon monoxide (CO) monitor to determine the smoking status of the patient. We used the response data to measure the individual smoking behavior by using a mixture item-response model. It is shown that the detected smokers scored significantly higher in the RR condition compared with the directly questioned condition. We proposed a Bayesian latent variable framework to evaluate the diagnostic test accuracy of the questionnaire using the randomized-response technique, which is based on the posterior densities of the subject's smoking behavior scores together with the breath test measurements. For different diagnostic test thresholds, we obtained moderate posterior mean estimates of sensitivity and specificity by observing a limited number of discrete randomized item responses. Copyright © 2013 John Wiley & Sons, Ltd.

  4. An Analytical Method of Identifying Biased Test Items.

    Science.gov (United States)

    Plake, Barbara S.; Hoover, H. D.

    1979-01-01

    A follow-up technique is needed to identify items contributing to items-by-groups interaction when using an ANOVA procedure to examine a test for biased items. The method described includes distribution theory for assessing level of significance and is sensitive to items at all difficulty levels. (Author/GSK)

  5. The Licensing of Negative Sensitive Items in Jordanian Arabic

    Science.gov (United States)

    Alsarayreh, Atef

    2012-01-01

    This study investigates the licensing conditions on Negative Sensitive Items (NSIs) in Jordanian Arabic (JA). JA exhibits both types of NSIs that are discussed in the literature: Negative Polarity Items (NPIs) and Negative Concord Items (NCIs). Although these two sets of items seem to form a natural class in the sense that they show certain…

  6. An optimized item-based collaborative filtering recommendation algorithm based on item genre prediction

    Science.gov (United States)

    Zhang, De-Jia

    2009-07-01

    With the fast development of Internet, many systems have emerged in e-commerce applications to support the product recommendation. Collaborative filtering is one of the most promising techniques in recommender systems, providing personalized recommendations to users based on their previously expressed preferences in the form of ratings and those of other similar users. In practice, with the adding of user and item scales, user-item ratings are becoming extremely sparsity and recommender systems utilizing traditional collaborative filtering are facing serious challenges. To address the issue, this paper presents an approach to compute item genre similarity, through mapping each item with a corresponding descriptive genre, and computing similarity between genres as similarity, then make basic predictions according to those similarities to lower sparsity of the user-item ratings. After that, item-based collaborative filtering steps are taken to generate predictions. Compared with previous methods, the presented collaborative filtering employs the item genre similarity can alleviate the sparsity issue in the recommender systems, and can improve accuracy of recommendation.

  7. Students' proficiency scores within multitrait item response theory

    Science.gov (United States)

    Scott, Terry F.; Schumayer, Daniel

    2015-12-01

    In this paper we present a series of item response models of data collected using the Force Concept Inventory. The Force Concept Inventory (FCI) was designed to poll the Newtonian conception of force viewed as a multidimensional concept, that is, as a complex of distinguishable conceptual dimensions. Several previous studies have developed single-trait item response models of FCI data; however, we feel that multidimensional models are also appropriate given the explicitly multidimensional design of the inventory. The models employed in the research reported here vary in both the number of fitting parameters and the number of underlying latent traits assumed. We calculate several model information statistics to ensure adequate model fit and to determine which of the models provides the optimal balance of information and parsimony. Our analysis indicates that all item response models tested, from the single-trait Rasch model through to a model with ten latent traits, satisfy the standard requirements of fit. However, analysis of model information criteria indicates that the five-trait model is optimal. We note that an earlier factor analysis of the same FCI data also led to a five-factor model. Furthermore the factors in our previous study and the traits identified in the current work match each other well. The optimal five-trait model assigns proficiency scores to all respondents for each of the five traits. We construct a correlation matrix between the proficiencies in each of these traits. This correlation matrix shows strong correlations between some proficiencies, and strong anticorrelations between others. We present an interpretation of this correlation matrix.

  8. How to repair an episiotomy.

    Science.gov (United States)

    Steen, Mary; Cummins, Bernie

    2016-02-17

    Rationale and key points Skilful repair of an episiotomy is an important aspect of maternal health care. It is essential that midwives and doctors have the knowledge and skills to undertake this procedure in a safe and effective manner. ▶ An episiotomy should be repaired promptly to reduce blood loss and prevent infection. ▶ Repair of an episiotomy is undertaken in three stages: repair of the vaginal mucosa, repair of the muscle layer and repair of the skin layer. ▶ Adequate pain relief should be provided before suturing. Reflective activity Clinical skills articles can help update your practice and ensure it remains evidence based. Apply this article to your practice. Reflect on and write a short account of: 1. Why a rectal examination is recommended before and following repair of an episiotomy. 2. What you would do to improve your suturing skills. 3. The factors that may prevent or delay an episiotomy from healing. Subscribers can upload their reflective accounts at rcni.com/portfolio .

  9. Optimal Buyer’s Replenishment Policy in the Integrated Inventory Model for Imperfect Items

    Directory of Open Access Journals (Sweden)

    Lu Yueli

    2016-01-01

    Full Text Available In the classical economic order quantity (EOQ models, a common unrealistic assumption is that all the items received are of good quality. However, in realistic environment, a received shipment usually contains a fraction of imperfect quality items. These imperfect items may be scrapped, reworked at a cost, or salvaged at a discounted price. While the percentage of imperfect items is random, the optimal ordering cycle is rarely considered in current literatures. This paper revisits the model (Maddah and Jaber, 2008 and extends it by assuming that the ordering cycle is determined by the demand rate, delivery quantity per shipment, and the mathematical expectation of the defective rate. The possibility of stockout or residue in the end of a cycle will be considered, and the loss of stockout and the salvage of the residue are counted into the cost. Besides, we consider consolidating the shipments of imperfect items over multiple deliveries. Thus, an integrated vendor-buyer inventory model for imperfect quality items with equal-size shipment policy is established to derive the optimal ordering cycle, ordering quantity, and number of deliveries. The computational method of the optimal delivery quantity per shipment and number of deliveries is given through theoretical results. Finally, sensitivity of main parameters is analyzed through simulation experiments and shown by some figures.

  10. Development of Abbreviated Eight-Item Form of the Penn Verbal Reasoning Test

    Science.gov (United States)

    Bilker, Warren B.; Wierzbicki, Michael R.; Brensinger, Colleen M.; Gur, Raquel E.; Gur, Ruben C.

    2014-01-01

    The ability to reason with language is a highly valued cognitive capacity that correlates with IQ measures and is sensitive to damage in language areas. The Penn Verbal Reasoning Test (PVRT) is a 29-item computerized test for measuring abstract analogical reasoning abilities using language. The full test can take over half an hour to administer, which limits its applicability in large-scale studies. We previously described a procedure for abbreviating a clinical rating scale and a modified procedure for reducing tests with a large number of items. Here we describe the application of the modified method to reducing the number of items in the PVRT to a parsimonious subset of items that accurately predicts the total score. As in our previous reduction studies, a split sample is used for model fitting and validation, with cross-validation to verify results. We find that an 8-item scale predicts the total 29-item score well, achieving a correlation of .9145 for the reduced form for the model fitting sample and .8952 for the validation sample. The results indicate that a drastically abbreviated version, which cuts administration time by more than 70%, can be safely administered as a predictor of PVRT performance. PMID:24577310

  11. Methods to Find the Number of Latent Skills

    Science.gov (United States)

    Beheshti, Behzad; Desmarais, Michel C.; Naceur, Rhouma

    2012-01-01

    Identifying the skills that determine the success or failure to exercises and question items is a difficult task. Multiple skills may be involved at various degree of importance, and skills may overlap and correlate. In an effort towards the goal of finding the skills behind a set of items, we investigate two techniques to determine the number of…

  12. Determining the Optimum Ordering Policy in Multi-Item Joint Replenishment Problem Using a Novel Method

    Directory of Open Access Journals (Sweden)

    Wen-Tsung Ho

    2013-01-01

    Full Text Available This work investigates the joint replenishment problem (JRP involving multiple items where economies exist for replenishing several items simultaneously. The demand rate for each item is known and constant. Shortages are not permitted and lead times are negligible. Many heuristic algorithms have been proposed to find quality solutions for the JRP. In this paper, cycle time division and recursive tightening methods are developed to calculate an efficient and optimal replenishment policy for JRP. Two theorems are demonstrated to guarantee that an optimal solution to the problem can be derived using cycle time division and recursive tightening methods. Restated, cycle time division and recursive tightening methods theoretically yield the optimal solution in 100% of instances. The complexity of cycle time division and recursive tightening methods is just O(NlogN, where N represents the number of items involved in the problem. Numerical examples are included to demonstrate the algorithmic procedures.

  13. Evolution and advances in laparoscopic ventral and incisional hernia repair

    Institute of Scientific and Technical Information of China (English)

    Alan; L; Vorst; Christodoulos; Kaoutzanis; Alfredo; M; Carbonell; Michael; G; Franz

    2015-01-01

    Primary ventral hernias and ventral incisional hernias have been a challenge for surgeons throughout the ages. In the current era, incisional hernias have increased in prevalence due to the very high number of laparotomies performed in the 20 th century. Even though minimally invasive surgery and hernia repair have evolved rapidly, general surgeons have yet to develop the ideal, standardized method that adequately decreases common postoperative complications, such as wound failure, hernia recurrence and pain. The evolution of laparoscopy and ventral hernia repair will be reviewed, from the rectoscopy of the 4th century to the advent of laparoscopy, from suture repair to the evolution of mesh reinforcement. The nuances of minimally invasive ventral and incisional hernia repair will be summarized, from preoperative considerations to variations in intraoperative practice. New techniques have become increasingly popular, such as primary defect closure, retrorectus mesh placement, and concomitant component separation. The advent of robotics has made some of these repairs more feasible, but only time and well-designed clinical studies will tell if this will be a durable modality for ventral and incisional hernia repair.

  14. 17 CFR 260.7a-16 - Inclusion of items, differentiation between items and answers, omission of instructions.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Inclusion of items... INDENTURE ACT OF 1939 Formal Requirements § 260.7a-16 Inclusion of items, differentiation between items and... application, statement, or report shall contain all of the items of the form as well as the answers...

  15. Differential Item Functioning Analysis of the Science and Mathematics Items in the University Entrance Examinations in Turkey

    Science.gov (United States)

    Kalaycioglu, Dilara Bakan; Berberoglu, Giray

    2011-01-01

    This study is aimed to detect differential item functioning (DIF) items across gender groups, analyze item content for the possible sources of DIF, and eventually investigate the effect of DIF items on the criterion-related validity of the test scores in the quantitative section of the university entrance examination (UEE) in Turkey. The reason…

  16. 40 CFR 798.5500 - Differential growth inhibition of repair proficient and repair deficient bacteria: “Bacterial DNA...

    Science.gov (United States)

    2010-07-01

    ... repair proficient and repair deficient bacteria: âBacterial DNA damage or repair tests.â 798.5500 Section... inhibition of repair proficient and repair deficient bacteria: “Bacterial DNA damage or repair tests.” (a... killing or growth inhibition of repair deficient bacteria in a set of repair proficient and deficient...

  17. Bone repair and stem cells.

    Science.gov (United States)

    Ono, Noriaki; Kronenberg, Henry M

    2016-10-01

    Bones are an important component of vertebrates; they grow explosively in early life and maintain their strength throughout life. Bones also possess amazing capabilities to repair-the bone is like new without a scar after complete repair. In recent years, a substantial progress has been made in our understanding on mammalian bone stem cells. Mouse genetic models are powerful tools to understand the cell lineage, giving us better insights into stem cells that regulate bone growth, maintenance and repair. Recent findings about these stem cells raise new questions that require further investigations.

  18. Repairing and Upgrading Your PC

    CERN Document Server

    Thompson, Robert

    2009-01-01

    Repairing and Upgrading Your PC delivers start-to-finish instructions, simple enough for even the most inexperienced PC owner, for troubleshooting, repairing, and upgrading your computer. Written by hardware experts Robert Bruce Thompson and Barbara Fritchman Thompson, this book covers it all: how to troubleshoot a troublesome PC, how to identify which components make sense for an upgrade, and how to tear it all down and put it back together. This book shows how to repair and upgrade all of your PC's essential components.

  19. Laparoscopic repair of incisional hernia.

    Science.gov (United States)

    Lau, H; Lee, F; Patil, N G

    2001-09-01

    A 75-year-old man developed an incisional hernia over the upper abdomen following a wedge resection of a gastric stromal tumour in 1996. This is the first published report of a successful repair of an incisional hernia via a laparoscopic intraperitoneal on-lay technique using GORE-TEX DualMesh material in Hong Kong. Compared with conventional open repair of incisional hernia, long incisions and wound tension are avoided using the laparoscopic approach. This translates into a reduced risk of wound-related complications and facilitates recovery. In selected cases, minimally invasive surgery is a safe technique for the repair of incisional hernias.

  20. [Inguinal and femoral hernia repair].

    Science.gov (United States)

    Geissler, B; Anthuber, M

    2011-05-01

    With an incidence of 200,000 new cases per year in Germany, inguinal hernia has a significant socioeconomic impact. The 2009 guidelines from the European Hernia Society established treatment recommendations. Hernia repair is based on reinforcing the posterior wall of the inguinal canal by suture or mesh repair by an anterior or posterior approach. Lightweight mesh reduces recurrence rates and is the treatment of choice even in primary hernias. Laparoscopic hernia repair is associated with specific risks but is superior in postoperative pain and earlier return to work.

  1. The quadratic relationship between difficulty of intelligence test items and their correlations with working memory

    Directory of Open Access Journals (Sweden)

    Tomasz eSmoleń

    2015-08-01

    Full Text Available Fluid intelligence (Gf is a crucial cognitive ability that involves abstract reasoning in order to solve novel problems. Recent research demonstrated that Gf strongly depends on the individual effectiveness of working memory (WM. We investigated a popular claim that if the storage capacity underlay the WM-Gf correlation, then such a correlation should increase with an increasing number of items or rules (load in a Gf test. As often no such link is observed, on that basis the storage-capacity account is rejected, and alternative accounts of Gf (e.g., related to executive control or processing speed are proposed. Using both analytical inference and numerical simulations, we demonstrated that the load-dependent change in correlation is primarily a function of the amount of floor/ceiling effect for particular items. Thus, the item-wise WM correlation of a Gf test depends on its overall difficulty, and the difficulty distribution across its items. When the early test items yield huge ceiling, but the late items do not approach floor, that correlation will increase throughout the test. If the early items locate themselves between ceiling and floor, but the late items approach floor, the respective correlation will decrease. For a hallmark Gf test, the Raven test, whose items span from ceiling to floor, the quadratic relationship is expected, and it was shown empirically using a large sample and two types of WMC tasks. In consequence, no changes in correlation due to varying WM/Gf load, or lack of them, can yield an argument for or against any theory of WM/Gf. Moreover, as the mathematical properties of the correlation formula make it relatively immune to ceiling/floor effects for overall moderate correlations, only minor changes (if any in the WM-Gf correlation should be expected for many psychological tests.

  2. The quadratic relationship between difficulty of intelligence test items and their correlations with working memory.

    Science.gov (United States)

    Smolen, Tomasz; Chuderski, Adam

    2015-01-01

    Fluid intelligence (Gf) is a crucial cognitive ability that involves abstract reasoning in order to solve novel problems. Recent research demonstrated that Gf strongly depends on the individual effectiveness of working memory (WM). We investigated a popular claim that if the storage capacity underlay the WM-Gf correlation, then such a correlation should increase with an increasing number of items or rules (load) in a Gf-test. As often no such link is observed, on that basis the storage-capacity account is rejected, and alternative accounts of Gf (e.g., related to executive control or processing speed) are proposed. Using both analytical inference and numerical simulations, we demonstrated that the load-dependent change in correlation is primarily a function of the amount of floor/ceiling effect for particular items. Thus, the item-wise WM correlation of a Gf-test depends on its overall difficulty, and the difficulty distribution across its items. When the early test items yield huge ceiling, but the late items do not approach floor, that correlation will increase throughout the test. If the early items locate themselves between ceiling and floor, but the late items approach floor, the respective correlation will decrease. For a hallmark Gf-test, the Raven-test, whose items span from ceiling to floor, the quadratic relationship is expected, and it was shown empirically using a large sample and two types of WMC tasks. In consequence, no changes in correlation due to varying WM/Gf load, or lack of them, can yield an argument for or against any theory of WM/Gf. Moreover, as the mathematical properties of the correlation formula make it relatively immune to ceiling/floor effects for overall moderate correlations, only minor changes (if any) in the WM-Gf correlation should be expected for many psychological tests.

  3. Transcript RNA supports precise repair of its own DNA gene.

    Science.gov (United States)

    Keskin, Havva; Meers, Chance; Storici, Francesca

    2016-01-01

    The transfer of genetic information from RNA to DNA is considered an extraordinary process in molecular biology. Despite the fact that cells transcribe abundant amount of RNA with a wide range of functions, it has been difficult to uncover whether RNA can serve as a template for DNA repair and recombination. An increasing number of experimental evidences suggest a direct role of RNA in DNA modification. Recently, we demonstrated that endogenous transcript RNA can serve as a template to repair a DNA double-strand break (DSB), the most harmful DNA lesion, not only indirectly via formation of a DNA copy (cDNA) intermediate, but also directly in a homology driven mechanism in budding yeast. These results point out that the transfer of genetic information from RNA to DNA is more general than previously thought. We found that transcript RNA is more efficient in repairing a DSB in its own DNA (in cis) than in a homologous but ectopic locus (in trans). Here, we summarize current knowledge about the process of RNA-driven DNA repair and recombination, and provide further data in support of our model of DSB repair by transcript RNA in cis. We show that a DSB is precisely repaired predominately by transcript RNA and not by residual cDNA in conditions in which formation of cDNA by reverse transcription is inhibited. Additionally, we demonstrate that defects in ribonuclease (RNase) H stimulate precise DSB repair by homologous RNA or cDNA sequence, and not by homologous DNA sequence carried on a plasmid. These results highlight an antagonistic role of RNase H in RNA-DNA recombination. Ultimately, we discuss several questions that should be addressed to better understand mechanisms and implications of RNA-templated DNA repair and recombination.

  4. Repair of Pd/α-Al2O3 composite membrane with defects

    Institute of Scientific and Technical Information of China (English)

    李安武; 熊国兴

    1999-01-01

    A palladium composite membrane with a large number of defects was repaired using the electroless plating combined with the technique of osmosis. The loose structure of palladium film prepared by the conventional electroless plating was densified. Defects were repaired. Hydrogen selectivity was thus significantly increased without significantly increasing palladium film thickness and reducing hydrogen permeability.

  5. Large myelomeningocele repair

    Directory of Open Access Journals (Sweden)

    Farideh Nejat

    2011-01-01

    Full Text Available Background: Wound closure is accomplished in most cases of myelomeningocele (MMC by undermining of the skin edges surrounding the defect. However, large defects cannot be closed reliably by this simple technique. Due to the technical challenge associated with large MMC, surgeons have devised different methods for repairing large defects. In this paper, we report our experience of managing large defects, which we believe bears a direct relationship to decrease the incidence of wound complications. Materials and Methods: Forty children with large MMCs underwent surgical repair and represent our experience. We recommend using all hairy skin around the defect as a way to decrease the tension on the edges of the wound and the possible subsequent necrosis. It is our experience that vertical incision on one or two flanks parallel to the midline can decrease the tension of the wound. Moreover, ventriculo-peritoneal shunting for children who developed hydrocephalus was performed simultaneously, which constitutes another recommendation for preventing fluid collection and build up of pressure on the wound. Results: Patients in this study were in the age range of 2 days to 8 years. The most common location of MMC was in the thoracolumbar area. All but four patients had severe weakness in lower extremities. We used as much hairy skin around the MMC sac as possible in all cases. Vertical incisions on one or both flanks and simultaneous shunt procedure were performed in 36 patients. We treated children with large MMC defects with acceptable tension-free closure. Nonetheless, three patients developed superficial skin infection and partial wound dehiscence, and they were managed conservatively. Conclusions: We recommend using all hairy skin around the MMC defect for closure of large defects. In cases that were expected to be at a higher risk to develop dehiscence release incisions on one or two flanks towards the fascia were found to be useful. Simultaneous

  6. Parametric studies on self-repairing approaches for resin infused composites subjected to low velocity impact

    Science.gov (United States)

    Motuku, M.; Vaidya, U. K.; Janowski, G. M.

    1999-10-01

    Low velocity impact response of glass reinforced polymer composites, which have the potential to self-repair both micro- and macro-damage, has been investigated. This class of material falls under the category of passive smart polymer composites. The self-repairing mechanism is achieved through the incorporation of hollow fibers in addition to the normal solid reinforcing fibers. The hollow fibers store the damage-repairing solution or chemicals that are released into the matrix or damaged zone upon fiber failure. Plain-weave S-2 glass fabric reinforcement, vinyl ester 411-C50 and EPON-862 epoxy resin systems were considered for this study. Different tubing materials were investigated for potential use as storage materials for the repairing chemicals instead of the actual hollow repair fibers and included borosilicate glass micro-capillary pipets, flint glass pasteur pipets, copper tubing and aluminum tubing. composite panels were fabricated by using a vacuum assisted resin transfer molding process. The present investigation addressed fabrication of self-repairing composite panels and some of the parameters that influence the response of self-repairing composites to impact loading. Specific issues addressed by this study include: the processing quality; the selection of storage material for the repairing solution; release and transportation of the repairing solution; the effect of the number, type and spatial distribution of the repairing tubes, specimen thickness, matrix material and impact energy level.

  7. Functional Analysis of Homologous Recombination Repair Proteins HerA and NurA in the Thermophile Sulfolobus islandicus

    DEFF Research Database (Denmark)

    Huang, Qihong

    A number of DNA lesions are generated in each cell every day, among which double-stranded breaks (DSBs) constitute one of the most detrimental types of DNA damage. DSBs lead to genome instability, cell death, or even tumorigenesis in human, if not repaired timely. Two main pathways are known...... for DSB repair, homologous recombination repair (HRR) and Non-homologous end joint (NHEJ). HR repairs DSBs using a homologous DNA molecule as a template resulting in error free DNA repair, whereas NHEJ promotes direct re-ligation of the broken DNA ends in an error-prone manner. In eukaryotes DSBs occurred...

  8. Differential Item Functioning on the International Personality Item Poolâ s Neuroticism Scale

    OpenAIRE

    McBride, Nadine LeBarron

    2008-01-01

    As use of the public-domain International Personality Item Pool (IPIP) scales has grown significantly over the past decade (Goldberg, Johnson, Eber, Hogan, Ashton, Cloninger, & Gough, 2006) research on the psychometric properties of the items and scales have become increasingly important. This research study examines the IPIP scale constructed to measure the Five Factor Model (FFM) domain of Neuroticism (as measured by the NEO-PI-R) for occurrences of differential functioning a...

  9. Validity Index and number of clusters

    Directory of Open Access Journals (Sweden)

    Mohamed Fadhel Saad

    2012-01-01

    Full Text Available Clustering (or cluster analysis has been used widely in pattern recognition, image processing, and data analysis. It aims to organize a collection of data items into c clusters, such that items within a cluster are more similar to each other than they are items in the other clusters. The number of clusters c is the most important parameter, in the sense that the remaining parameters have less influence on the resulting partition. To determine the best number of classes several methods were made, and are called validity index. This paper presents a new validity index for fuzzy clustering called a Modified Partition Coefficient And Exponential Separation (MPCAES index. The efficiency of the proposed MPCAES index is compared with several popular validity indexes. More information about these indexes is acquired in series of numerical comparisons and also real data Iris.

  10. A deteriorating two-system with two repair modes and sojourn times phase-type distributed

    Energy Technology Data Exchange (ETDEWEB)

    Montoro-Cazorla, Delia [Departamento de Estadistica e I.O., Escuela Politecnica de Linares, Universidad de Jaen, 23700 Linares, Jaen (Spain); Perez-Ocon, Rafael [Departamento de Estadistica e I.O., Facultad de Ciencias, Universidad de Granada, Granada 18071 (Spain)]. E-mail: rperezo@ugr.es

    2006-01-01

    We study a two-unit cold standby system in steady-state. The online unit goes through a finite number of stages of successive degradation preceding the failure. The units are reparable, there is a repairman and two types of maintenance are considered, preventive and corrective. The preventive repair aims to improve the degradation of a unit being operative. The corrective repair is necessary when the unit fails. We will assume that the preventive repair will be interrupted in favour of a corrective repair in order to increase the availability of the system. The random operational and repair times follow phase-type distributions. For this system, the stationary probability vector, the replacement times, and the involved costs are calculated. An optimisation problem is illustrated by a numerical example. In this, the optimal degradation stage for the preventive repair of the online unit is determined by taking into account the system availability and the incurred costs.

  11. Current advances in DNA repair: regulation of enzymes and pathways involved in maintaining genomic stability.

    Science.gov (United States)

    Neher, Tracy M; Turchi, John J

    2011-06-15

    Novel discoveries in the DNA repair field have lead to continuous and rapid advancement of our understanding of not only DNA repair but also DNA replication and recombination. Research in the field transcends numerous areas of biology, biochemistry, physiology, and medicine, making significant connections across these broad areas of study. From early studies conducted in bacterial systems to current analyses in eukaryotic systems and human disease, the innovative research into the mechanisms of repair machines and the consequences of ineffective DNA repair has impacted a wide scientific community. This Forum contains a select mix of primary research articles in addition to a number of timely reviews covering a subset of DNA repair pathways where recent advances and novel discoveries are improving our understanding of DNA repair, its regulation, and implications to human disease.

  12. Item Screening in Graphical Loglinear Rasch Models

    DEFF Research Database (Denmark)

    Kreiner, Svend; Christensen, Karl Bang

    2011-01-01

    the initial item analysis may disclose a great deal of spurious and misleading evidence of DIF and local dependence that has to disposed of during the modelling procedure. Like graphical models, graphical loglinear Rasch models possess Markov properties that are useful during the statistical analysis......In behavioural sciences, local dependence and DIF are common, and purification procedures that eliminate items with these weaknesses often result in short scales with poor reliability. Graphical loglinear Rasch models (Kreiner & Christensen, in Statistical Methods for Quality of Life Studies, ed....... by M. Mesbah, F.C. Cole & M.T. Lee, Kluwer Academic, pp. 187–203, 2002) where uniform DIF and uniform local dependence are permitted solve this dilemma by modelling the local dependence and DIF. Identifying loglinear Rasch models by a stepwise model search is often very time consuming, since...

  13. Teoria de la respuesta al item

    OpenAIRE

    2009-01-01

    A preocupação com medidas de traços psicológicos é antiga, sendo que muitos estudos e propostas de métodos foram desenvolvidos no sentido de alcançar este objetivo. Entre os trabalhos propostos, destaca-se a Teoria da Resposta ao Item (TRI) que, a princípio, veio completar limitações da Teoria Clássica de Medidas, empregada em larga escala até hoje na medida de traços psicológicos. O ponto principal da TRI é que ela leva em consideração o item particularmente, sem relevar os escores totais; p...

  14. Global positive polarity items and obligatory exhaustivity

    Directory of Open Access Journals (Sweden)

    Benjamin Spector

    2014-11-01

    Full Text Available I argue for a distinction between two types of positive polarity items (PPIs which has not been recognized so far. While for some PPIs, anti-licensing is a strictly local phenomenon, for other PPIs anti-licensing should be stated as a global condition. I aim to contribute to a principled explanation for the distribution of a significant subset of global PPIs, by relating it to specific semantic properties of the relevant items. More specifically, I argue that PPIs such as soit ... soit ..., quelques and almost trigger obligatory exhaustivity effects and scalar inferences, and that independently motivated constraints regarding the generation of such inferences can account for their distribution. The paper also briefly addresses the case of other global PPIs, e.g., at least, for which a similar account is not straightforwardly available. http://dx.doi.org/10.3765/sp.7.11 BibTeX info

  15. A Two-Unit Cold Standby Repairable System with One Replaceable Repair Facility and Delay Repair:Some Reliability Problems

    Institute of Scientific and Technical Information of China (English)

    WEI Ying-yuan; TANG Ying-hui

    2004-01-01

    This paper considers a two-unit same cold standby repairable system with a replaceable repair facility and delay repair .The failure time of unit is assumed to follow exponential distribution , and the repair time and delay time of failed unit are assumed to follow arbitrary distributions , whereas the failure and replacement time distributions of the repair facility are exponential and arbitrary . By using the Markov renewal process theory, some primary reliability quantities of the system are obtained.

  16. 40 CFR 63.1024 - Leak repair.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Leak repair. 63.1024 Section 63.1024... Standards for Equipment Leaks-Control Level 2 Standards § 63.1024 Leak repair. (a) Leak repair schedule. The owner or operator shall repair each leak detected as soon as practical, but not later than 15...

  17. 40 CFR 65.105 - Leak repair.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Leak repair. 65.105 Section 65.105... FEDERAL AIR RULE Equipment Leaks § 65.105 Leak repair. (a) Leak repair schedule. The owner or operator shall repair each leak detected as soon as practical but not later than 15 calendar days after it...

  18. 40 CFR 63.1005 - Leak repair.

    Science.gov (United States)

    2010-07-01

    ... successful repair of the leak. (3) Maximum instrument reading measured by Method 21 of 40 CFR part 60... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Leak repair. 63.1005 Section 63.1005... Standards for Equipment Leaks-Control Level 1 § 63.1005 Leak repair. (a) Leak repair schedule. The owner...

  19. An item factor analysis and item response theory-based revision of the Everyday Discrimination Scale.

    Science.gov (United States)

    Stucky, Brian D; Gottfredson, Nisha C; Panter, A T; Daye, Charles E; Allen, Walter R; Wightman, Linda F

    2011-04-01

    The Everyday Discrimination Scale (EDS), a widely used measure of daily perceived discrimination, is purported to be unidimensional, to function well among African Americans, and to have adequate construct validity. Two separate studies and data sources were used to examine and cross-validate the psychometric properties of the EDS. In Study 1, an exploratory factor analysis was conducted on a sample of African American law students (N = 589), providing strong evidence of local dependence, or nuisance multidimensionality within the EDS. In Study 2, a separate nationally representative community sample (N = 3,527) was used to model the identified local dependence in an item factor analysis (i.e., bifactor model). Next, item response theory (IRT) calibrations were conducted to obtain item parameters. A five-item, revised-EDS was then tested for gender differential item functioning (in an IRT framework). Based on these analyses, a summed score to IRT-scaled score translation table is provided for the revised-EDS. Our results indicate that the revised-EDS is unidimensional, with minimal differential item functioning, and retains predictive validity consistent with the original scale.

  20. NBC Contamination Survivability, Large Item Exteriors

    Science.gov (United States)

    2007-11-02

    Perform these tasks (timed) in the standard garment. .(3) Perform these tasks (timed) in mission-oriented protective posture level 4 (MOPP4). (4...bring the chamber to the environmental conditions specified for the test. Condition the test item until it has equilibrated at 30±50 C. Temperature and...condition that all essential operations can be continued in the lowest protective posture consistent with the mission and threat, and without long-term

  1. Early days of DNA repair: discovery of nucleotide excision repair and homology-dependent recombinational repair.

    Science.gov (United States)

    Rupp, W Dean

    2013-12-13

    The discovery of nucleotide excision repair in 1964 showed that DNA could be repaired by a mechanism that removed the damaged section of a strand and replaced it accurately by using the remaining intact strand as the template. This result showed that DNA could be actively metabolized in a process that had no precedent. In 1968, experiments describing postreplication repair, a process dependent on homologous recombination, were reported. The authors of these papers were either at Yale University or had prior Yale connections. Here we recount some of the events leading to these discoveries and consider the impact on further research at Yale and elsewhere.

  2. Construction, repair and maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Hinger, R. [Terasen Pipelines, Calgary, AB (Canada); Wong, P. [KC Integrity Corp., Calgary, AB (Canada); Yeomans, M.; Glover, A. [TransCanada PipeLines Ltd., Calgary, AB (Canada)

    2003-07-01

    The presentations by Working Group 4 focused on construction, repair and maintenance of pipelines with particular reference to high-strength steels and their applications for natural gas transmission pipelines. Discussions focused on how technology can be used to provide cost-effective design and construction solutions for long distance pipelines in a manner that does not compromise safety and reliability. The role that carbon plays in increasing the toughness of steel was also discussed. A few fundamental changes in steel production technology and a reduction in carbon content can result in a simultaneous increase in strength and toughness of steels. The cost impact of this technology was summarized. It was concluded that high strength steels offer effective solutions to deliver cost-effective pipelines to transport natural gas from northern basins. This session also presented pipeline routes that transport diluted bitumens from the Athabasca Oil Sands Project and the Muskeg River Mine to upgrader facilities in Alberta. Construction issues included design conservatism, water course crossings, winter construction, winter ditching, and public consultation. Examples of high strength steel pipe applications were also included with reference to experience gained by TransCanada and Corridor Pipeline. tabs., figs.

  3. Grammatical typology and frequency analysis: number availability and number use

    Directory of Open Access Journals (Sweden)

    Dunstan Brown

    2013-12-01

    Full Text Available The Smith-Stark hierarchy, a version of the Animacy Hierarchy, offers a typology of the cross-linguistic availability of number. The hierarchy predicts that the availability of number is not arbitrary. For any language, if the expression of plural is available to a noun, it is available to any noun of a semantic category further to the left of the hierarchy. In this article we move one step further by showing that the structure of the hierarchy can be observed in a statistical model of number use in Russian. We also investigate three co-variates: plural preference, pluralia tantum and irregularity effects; these account for an item's behaviour being different than that solely expected from its animacy position.

  4. Laparoscopic repair of postoperative perineal hernia.

    LENUS (Irish Health Repository)

    Ryan, Stephen

    2010-01-01

    Perineal hernias are infrequent complications following abdominoperineal operations. Various approaches have been described for repair of perineal hernias including open transabdominal, transperineal or combined abdominoperineal repairs. The use of laparoscopic transabdominal repair of perineal hernias is not well-described. We present a case report demonstrating the benefits of laparoscopic repair of perineal hernia following previous laparoscopic abdominoperineal resection (APR) using a nonabsorbable mesh to repair the defect. We have demonstrated that the use of laparoscopy with repair of the pelvic floor defect using a non absorbable synthetic mesh offers an excellent alternative with many potential advantages over open transabdominal and transperineal repairs.

  5. Umbilical and epigastric hernia repair.

    Science.gov (United States)

    Muschaweck, Ulrike

    2003-10-01

    The repair of umbilical and epigastric hernias still represents a challenge to surgeons. Although a common and relatively simple procedure, there is no exact protocol today on how the repair should be done. The Mayo technique and its alterations could not stand the test of time: a recurrence rate of 20% and higher is not acceptable for any surgical procedure. Although there is no consensus opinion, one thing is clear: the importance of an anatomic repair without tension and without an artificial enlargement of the defect. In 1987 Lichtenstein reported on 6321 cases of herniorraphy with a tension free repair, and in 1994 Stuart reemphasized that special importance in his editorial in the Lancet. A newer study from Brancato and coworkers in Italy also states the advantage of a tension-free prosthetic repair in 16 patients with epigastric hernia. We have gone even further and recommend a tailored-to-the-patient repair using a customized polypropylene mesh and a one-layer running suture. The advantages should be obvious: no artificial creation of an even bigger than original defect, a completely tension-free repair, and little to no recurrence of the hernia. Our results clearly prove that assumption. Moreover, the procedure is extremely safe and complications are very rare and minor. We conclude that using a mesh plug in a customized tension-free repair of umbilical and epigastric hernia shows many advantages over the commonly used methods. And we finally conclude with the words of Albert Einstein: "The only source of knowledge is experience."

  6. Repair Types, Procedures - Part 1

    Science.gov (United States)

    2010-05-01

    New Jersey, USA. Repair Types, Procedures – Part I RTO-EN-AVT-156 9 - 19 [5] Drieker R, Botello C, MacBeth S, and Grody J, “Aircraft Battle... MacBeth S, and Grody J, “Aircraft Battle Damage Assessment and Repair (ABDAR), Vol. III: Field Test Report,” AFRL-HE-WP-TR-2002-0039, July 2000. [8

  7. Hand function after nerve repair.

    OpenAIRE

    Lundborg, Göran; Rosén, Birgitta

    2007-01-01

    Treatment of injuries to major nerve trunks in the hand and upper extremity remains a major and challenging reconstructive problem. Such injuries may cause long-lasting disabilities in terms of lost fine sensory and motor functions. Nowadays there is no surgical repair technique that can ensure recovery of tactile discrimination in the hand of an adult patient following nerve repair while very young individuals usually regain a complete recovery of functional sensibility. Post-traumatic nerve...

  8. Cobbler's technique for Iridodialysis repair

    Directory of Open Access Journals (Sweden)

    Surinder Singh Pandav

    2016-01-01

    Full Text Available We describe a novel “Cobbler's technique” for iridodialysis repair in the right eye of a patient aged 18 years, with a traumatic iridodialysis secondary to open globe injury with an iron rod. Our technique is simple with easy surgical maneuvers, that is, effective for repairing iridodialysis. The “Cobbler's technique” allows a maximally functional and cosmetic result for iridodialysis.

  9. Rehabilitation after Rotator Cuff Repair.

    Science.gov (United States)

    Nikolaidou, Ourania; Migkou, Stefania; Karampalis, Christos

    2017-01-01

    Rotator cuff tears are a very common condition that is often incapacitating. Whether non-surgical or surgical, successful management of rotator cuff disease is dependent on appropriate rehabilitation. If conservative management is insufficient, surgical repair is often indicated. Postsurgical outcomes for patients having had rotator cuff repair can be quite good. A successful outcome is much dependent on surgical technique as it is on rehabilitation. Numerous rehabilitation protocols for the management of rotator cuff disease are based primarily on clinical experience and expert opinion. This article describes the different rehabilitation protocols that aim to protect the repair in the immediate postoperative period, minimize postoperative stiffness and muscle atrophy. A review of currently available literature on rehabilitation after arthroscopic rotator cuff tear repair was performed to illustrate the available evidence behind various postoperative treatment modalities. There were no statistically significant differences between a conservative and an accelerated rehabilitation protocol . Early passive range of motion (ROM) following arthroscopic cuff repair is thought to decrease postoperative stiffness and improve functionality. However, early aggressive rehabilitation may compromise repair integrity. The currently available literature did not identify any significant differences in functional outcomes and relative risks of re-tears between delayed and early motion in patients undergoing arthroscopic rotator cuff repairs. A gentle rehabilitation protocol with limits in range of motion and exercise times after arthroscopic rotator cuff repair would be better for tendon healing without taking any substantial risks. A close communication between the surgeon, the patient and the physical therapy team is important and should continue throughout the whole recovery process.

  10. Repairing Learned Knowledge Using Experience

    Science.gov (United States)

    1990-05-01

    It necessar and Identify by’ 6109h nii be) learning precedent-based learning knowledge repair explanation-based learning near - miss groups 20. ABSTRACT...can a program use explanations to repair a recollection, preventing further misapplication? Near - Miss Groups Isolate Suspicious Relations If a metal...pail differs from a porcelain cup only in the position of handle attachment, then we would say that the pail is a near miss . Unfortunately, there are

  11. CTTITEM: SAS macro and SPSS syntax for classical item analysis.

    Science.gov (United States)

    Lei, Pui-Wa; Wu, Qiong

    2007-08-01

    This article describes the functions of a SAS macro and an SPSS syntax that produce common statistics for conventional item analysis including Cronbach's alpha, item difficulty index (p-value or item mean), and item discrimination indices (D-index, point biserial and biserial correlations for dichotomous items and item-total correlation for polytomous items). These programs represent an improvement over the existing SAS and SPSS item analysis routines in terms of completeness and user-friendliness. To promote routine evaluations of item qualities in instrument development of any scale, the programs are available at no charge for interested users. The program codes along with a brief user's manual that contains instructions and examples are downloadable from suen.ed.psu.edu/-pwlei/plei.htm.

  12. Assessing the Psychometric Properties of Alternative Items for Certification.

    Science.gov (United States)

    Krogh, Mary Anne; Muckle, Timothy

    Alternative items were added as scored items to the National Certification Examination for Nurse Anesthetists (NCE) in 2010. A common concern related to the new items has been their measurement attributes. This study was undertaken to evaluate the psychometric impact of adding these items to the examination. Candidates had a significantly higher ability estimate in alternative items than in multiple choice questions and 6.7 percent of test candidates performed significantly differently in alternative item formats. The ability estimates of multiple choice questions correlated at r = .58. The alternative items took significantly longer time to answer than standard multiple choice questions and discriminated to a higher degree than MCQs. The alternative items exhibited unidimensionality to the same degree as MCQs and the BIC confirmed the Rasch model as acceptable for scoring. The new item types were found to have acceptable attributes for inclusion in the certification program.

  13. Aircraft Metal Skin Repair and Honeycomb Structure Repair; Sheet Metal Work 3: 9857.02.

    Science.gov (United States)

    Dade County Public Schools, Miami, FL.

    The course helps students determine types of repairs, compute repair sizes, and complete the repair through surface protection. Course content includes goals, specific objectives, protection of metals, repairs to metal skin, and honeycomb structure repair. A bibliography and post-test are appended. A prerequisite for this course is mastery of the…

  14. Reliability and validity of the Spanish version of the 10-item Connor-Davidson Resilience Scale (10-item CD-RISC in young adults

    Directory of Open Access Journals (Sweden)

    García-Campayo Javier

    2011-08-01

    Full Text Available Abstract Background The 10-item Connor-Davidson Resilience Scale (10-item CD-RISC is an instrument for measuring resilience that has shown good psychometric properties in its original version in English. The aim of this study was to evaluate the validity and reliability of the Spanish version of the 10-item CD-RISC in young adults and to verify whether it is structured in a single dimension as in the original English version. Findings Cross-sectional observational study including 681 university students ranging in age from 18 to 30 years. The number of latent factors in the 10 items of the scale was analyzed by exploratory factor analysis. Confirmatory factor analysis was used to verify whether a single factor underlies the 10 items of the scale as in the original version in English. The convergent validity was analyzed by testing whether the mean of the scores of the mental component of SF-12 (MCS and the quality of sleep as measured with the Pittsburgh Sleep Index (PSQI were higher in subjects with better levels of resilience. The internal consistency of the 10-item CD-RISC was estimated using the Cronbach α test and test-retest reliability was estimated with the intraclass correlation coefficient. The Cronbach α coefficient was 0.85 and the test-retest intraclass correlation coefficient was 0.71. The mean MCS score and the level of quality of sleep in both men and women were significantly worse in subjects with lower resilience scores. Conclusions The Spanish version of the 10-item CD-RISC showed good psychometric properties in young adults and thus can be used as a reliable and valid instrument for measuring resilience. Our study confirmed that a single factor underlies the resilience construct, as was the case of the original scale in English.

  15. Common data items in seven European oesophagogastric cancer surgery registries: towards a European upper GI cancer audit (EURECCA Upper GI).

    Science.gov (United States)

    de Steur, W O; Henneman, D; Allum, W H; Dikken, J L; van Sandick, J W; Reynolds, J; Mariette, C; Jensen, L; Johansson, J; Kolodziejczyk, P; Hardwick, R H; van de Velde, C J H

    2014-03-01

    Seven countries (Denmark, France, Ireland, the Netherlands, Poland, Sweden, United Kingdom) collaborated to initiate a EURECCA (European Registration of Cancer Care) Upper GI project. The aim of this study was to identify a core dataset of shared items in the different data registries which can be used for future collaboration between countries. Item lists from all participating Upper GI cancer registries were collected. Items were scored 'present' when included in the registry, or when the items could be deducted from other items in the registry. The definition of a common item was that it was present in at least six of the seven participating countries. The number of registered items varied between 40 (Poland) and 650 (Ireland). Among the 46 shared items were data on patient characteristics, staging and diagnostics, neoadjuvant treatment, surgery, postoperative course, pathology, and adjuvant treatment. Information on non-surgical treatment was available in only 4 registries. A list of 46 shared items from seven participating Upper GI cancer registries was created, providing a basis for future quality assurance and research in Upper GI cancer treatment on a European level. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Aging and DNA repair capability. [Review

    Energy Technology Data Exchange (ETDEWEB)

    Tice, R R

    1977-01-01

    A review of the literature on DNA repair processes in relation to aging is presented under the following headings: DNA repair processes; age-related occurrence of unrepaired DNA lesions; DNA repair capability as a function of age; tissue-specific DNA repair capability; acceleration of the aging process by exposure to DNA damaging agents; human genetic syndromes; and longevity and DNA repair processes. (HLW)

  17. Faculty development programs improve the quality of Multiple Choice Questions items' writing.

    Science.gov (United States)

    Abdulghani, Hamza Mohammad; Ahmad, Farah; Irshad, Mohammad; Khalil, Mahmoud Salah; Al-Shaikh, Ghadeer Khalid; Syed, Sadiqa; Aldrees, Abdulmajeed Abdurrahman; Alrowais, Norah; Haque, Shafiul

    2015-04-01

    The aim of this study was to assess the utility of long term faculty development programs (FDPs) in order to improve the quality of multiple choice questions (MCQs) items' writing. This was a quasi-experimental study, conducted with newly joined faculty members. The MCQ items were analyzed for difficulty index, discriminating index, reliability, Bloom's cognitive levels, item writing flaws (IWFs) and MCQs' nonfunctioning distractors (NFDs) based test courses of respiratory, cardiovascular and renal blocks. Significant improvement was found in the difficulty index values of pre- to post-training (p = 0.003). MCQs with moderate difficulty and higher discrimination were found to be more in the post-training tests in all three courses. Easy questions were decreased from 36.7 to 22.5%. Significant improvement was also reported in the discriminating indices from 92.1 to 95.4% after training (p = 0.132). More number of higher cognitive level of Bloom's taxonomy was reported in the post-training test items (p<0.0001). Also, NFDs and IWFs were reported less in the post-training items (p<0.02). The MCQs written by the faculties without participating in FDPs are usually of low quality. This study suggests that newly joined faculties need active participation in FDPs as these programs are supportive in improving the quality of MCQs' items writing.

  18. 49 CFR 1242.42 - Administration, repair and maintenance, machinery repair, equipment damaged, dismantling retired...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Administration, repair and maintenance, machinery repair, equipment damaged, dismantling retired property, fringe benefits, other casualties and insurance... maintenance, machinery repair, equipment damaged, dismantling retired property, fringe benefits,...

  19. Holding Multiple Items in Short Term Memory: A Neural Mechanism

    Science.gov (United States)

    Rolls, Edmund T.; Dempere-Marco, Laura; Deco, Gustavo

    2013-01-01

    Human short term memory has a capacity of several items maintained simultaneously. We show how the number of short term memory representations that an attractor network modeling a cortical local network can simultaneously maintain active is increased by using synaptic facilitation of the type found in the prefrontal cortex. We have been able to maintain 9 short term memories active simultaneously in integrate-and-fire simulations where the proportion of neurons in each population, the sparseness, is 0.1, and have confirmed the stability of such a system with mean field analyses. Without synaptic facilitation the system can maintain many fewer memories active in the same network. The system operates because of the effectively increased synaptic strengths formed by the synaptic facilitation just for those pools to which the cue is applied, and then maintenance of this synaptic facilitation in just those pools when the cue is removed by the continuing neuronal firing in those pools. The findings have implications for understanding how several items can be maintained simultaneously in short term memory, how this may be relevant to the implementation of language in the brain, and suggest new approaches to understanding and treating the decline in short term memory that can occur with normal aging. PMID:23613789

  20. Household item ownership and self-rated health: material and psychosocial explanations

    Directory of Open Access Journals (Sweden)

    Rose Richard

    2003-11-01

    Full Text Available Abstract Background There has been an ongoing debate whether the effects of socioeconomic factors on health are due to absolute poverty and material factors or to relative deprivation and psychosocial factors. In the present analyses, we examined the importance for health of material factors, which may have a direct effect on health, and of those that may affect health indirectly, through psychosocial mechanisms. Methods Random national samples of men and women in Hungary (n = 973 and Poland (n = 1141 were interviewed (response rates 58% and 59%, respectively. The subjects reported their self-rated health, socioeconomic circumstances, including ownership of different household items, and perceived control over life. Household items were categorised as "basic needs", "socially oriented", and "luxury". We examined the association between the ownership of different groups of items and self-rated health. Since the lists of household items were different in Hungary and Poland, we conducted parallel identical analyses of the Hungarian and Polish data. Results The overall prevalence of poor or very poor health was 13% in Poland and 25% in Hungary. Education, material deprivation and the number of household items were all associated with poor health in bivariate analyses. All three groups of household items were positively related to self-rated health in age-adjusted analyses. The relation of basic needs items to poor health disappeared after controlling for other socioeconomic variables (mainly material deprivation. The relation of socially oriented and luxury items to poor health, however, persisted in multivariate models. The results were similar in both datasets. Conclusions These data suggest that health is influenced by both material and psychosocial aspects of socioeconomic factors.

  1. Approaches to diagnose DNA mismatch repair gene defects in cancer

    DEFF Research Database (Denmark)

    Peña-Diaz, Javier; Rasmussen, Lene Juel

    2016-01-01

    The DNA repair pathway mismatch repair (MMR) is responsible for the recognition and correction of DNA biosynthetic errors caused by inaccurate nucleotide incorporation during replication. Faulty MMR leads to failure to address the mispairs or insertion deletion loops (IDLs) left behind...... already been well defined and their pathogenicity assessed. Despite this substantial wealth of knowledge, the effects of a large number of alterations remain uncharacterized (variants of uncertain significance, VUSs). The advent of personalized genomics is likely to increase the list of VUSs found in MMR...

  2. Vascular smooth muscle progenitor cells: building and repairing blood vessels.

    Science.gov (United States)

    Majesky, Mark W; Dong, Xiu Rong; Regan, Jenna N; Hoglund, Virginia J

    2011-02-04

    Molecular pathways that control the specification, migration, and number of available smooth muscle progenitor cells play key roles in determining blood vessel size and structure, capacity for tissue repair, and progression of age-related disorders. Defects in these pathways produce malformations of developing blood vessels, depletion of smooth muscle progenitor cell pools for vessel wall maintenance and repair, and aberrant activation of alternative differentiation pathways in vascular disease. A better understanding of the molecular mechanisms that uniquely specify and maintain vascular smooth muscle cell precursors is essential if we are to use advances in stem and progenitor cell biology and somatic cell reprogramming for applications directed to the vessel wall.

  3. Pengendalian Persediaan Primary Items dalam Logistik Konstruksi

    Directory of Open Access Journals (Sweden)

    Lady Lisya

    2016-09-01

    Full Text Available Construction logistics are activities that consist of ordering, storage and transportation of materials of construction projects. Storage material is logistics activity that ensure the availability of materials in project site. Generally, material storage activities have been conducted at the project site. Logistics construction is aimed to support the project activities that the completion schedule has been set. Construction logistics issues is determining the schedule of ordering materials so that the project can be implemented on schedule. The purpose of research is to determine the optimum ordering period for the primary items on the main building structure construction and designing inventory control cards as a mechanism for monitoring procurement of materials. This research has been obtained optimal ordering period for the primary items of main building structure with elements of the work using Fixed Period Requirement method. Inventories were already meet the material requirement of each period. Material management has been conducted based grouping approach as many as 31 groups. In addition, this research has proposed the inventory control cards as an instrument for material procurement monitoring. The implications of inventory control cards are coordinate contracting parties with vendors to plan the replenishment  of materials to meet the work schedule. Further research can be developed with other aspects such as integrated material order system between contractors and vendors to consider the safety stock. In addition, the information system for planning material is an important consideration for construction projects with large scale so that the companies can plan primary items inventory and other materials in the projects completion more easily, quickly and accurately.

  4. Laparoscopic and open incisional hernia repair: A prospective randomized study

    Directory of Open Access Journals (Sweden)

    Mehmet Zafer Sabuncuoğlu

    2015-07-01

    Full Text Available As the number of major surgical procedures has increased in recent years, so there has been an increase in incisional hernias. With gained experience and new materials, laparoscopic repair of incisional hernia is now applied. This study was aimed to compare the results of incisional hernia repair with the open surgery or laparoscopic approach at the only centre in the region for laparoscopic incisional hernia repair. A total of 55 cases of incisional hernia at the General Surgery Clinic of SDU between November 2012 and 2014 were underwent laparoscopic ventral hernia repair (L-VHR and conventional incisional hernia repair (C-VHR. From the L-VHR group 6 cases and from the C-VHR 9 cases were excluded from the study, as they did not meet the inclusion criteria or did not wish to participate in the study. The two techniques were compared in respect of operative time, length of hospital stay, postoperative pain scores, complications and recurrence. A total of 40 cases of incisional hernia repair were evaluated. The mean follow-up period was found as 12.75±4.19 months. No difference was determined between the characteristics of the patients due to age, body mass index, American Society of Anesthesiologists (ASA score, comorbidities, hernia size, and follow-up. In the laparoscopic repair group, the postoperative pain scores, complication rates and duration of hospital stay were found significantly superior to those of the open technique group. While there was no mortality seen and wound complications as a morbidity were 0 % in the L-VHR (n = 0 and 20 % in C-VHR group (n = 4. In the comparison of mean operative time, the duration of surgery was significantly shorter in the laparoscopic repair group (67.25±19.23 min compared to the open technique group (91.50±24.87 min (p=0.001. Laparoscopic repair was associated with less postoperative pain (4.35±1.03 vs 5.60±1.31, p=0.002, lesser postoperative complications (5% vs. 35%, p=0.044, and shorter

  5. A NEW ASSOCIATION RULE MINING BASED ON FREQUENT ITEM SET

    Directory of Open Access Journals (Sweden)

    Ms. Sanober Shaikh

    2011-09-01

    Full Text Available In this paper a new mining algorithm is defined based on frequent item set. Apriori Algorithm scans the database every time when it finds the frequent item set so it is very time consuming and at each step it generates candidate item set. So for large databases it takes lots of space to store candidate item set. The defined algorithm scans the database at the start only once and then makes the undirected item set graph. From this graph by considering minimum support it finds the frequent item set and by considering the minimum confidence it generates the association rule. If database and minimum support is changed, the new algorithm finds the new frequent items by scanning undirected item set graph. That is why it’s executing efficiency is improved distinctly compared to traditional algorithm.

  6. Peeking into personality test answers: inter- and intraindividual variety in item interpretations.

    Science.gov (United States)

    Arro, Grete

    2013-03-01

    Personality research of today applies basically inventories having neither unambiguously interpretable items nor responses. The substantive process of generating the test answer is rarely investigated and thus the possible field of meanings, out of which the answer is created, remains hidden. In order to investigate the possible array of spontaneous answers to personality test items, a situative open-ended personality inventory was developed to determine individuals' ways of interpreting personality test items and relevant personality descriptions for individuals. The children's sample (N = 704 of 10-13 year olds) answered five free-response contextualized personality test questions, each related to one of the Five Factor Model personality dimensions. It was revealed that there is no universal interpretation of an item. First, different children's answers to same question described different personality dimensions - substantial number of the respondents' answers did not reflect the personality domain assumed in an item. So there are several ways to interpret test questions; answers may refer to different personality dimensions and not necessarily the one assumed by the researcher. Second, a number of children mentioned more than one personality trait for one item, indicating that even within one person there may be several relevant interpretations of the same item. Considering personality traits as occurring one by one and mutually exclusively during personality test answering may be artificial; in reality trait combinations may reflect actual reaction. In sum, the results suggest there is no single predictable interpretational trajectory in meaning construction process if semiotically mediated constructs, e.g., personality reflection, are assessed.

  7. The effect of television news items on intimate partner violence murders.

    Science.gov (United States)

    Vives-Cases, C; Torrubiano-Domínguez, J; Alvarez-Dardet, C

    2009-12-01

    This study has been carried out in order to explore the effect of the growing appearance of IPV in television news items on deaths by this cause. Ecological study based on 340 deaths by intimate partner violence (IPV) and 3733 television news items covering this topic on Spanish television channels (2003 and 2007). Logistic regression analysis was carried out. Dependent variable: the difference between the number of IPV deaths in the 7 days following a news item broadcast and the number of IPV deaths in the 7 days before a media item. This outcome variable was conceptualised as a binary variable: increase vs. no increase. days with IPV news items-in general, concerning deaths, measures or other IPV crimes. Adjusted variables: day of the week, month, year and public holidays. A small copycat effect was observed in the IPV murder rate (RR = 1.32, CI(95%) = 1.07 - 1.62) for IPV-related news item days compared with days without such news. This effect continued when information about deaths was broadcast (RR = 1.28, CI(95%) = 1.01 - 1.62). News items concerning measures (RR = 0.90, CI(95%) = 0.82 - 0.98) or other IPV crimes (0.84, CI(95%) = 0.82 - 0.98) were related to a lower possibility of an increase in deaths compared with days with death-related news. Given the results observed in the case of IPV-related news, there is an evident need to develop a journalistic style guide in order to determine what type of information is recommended due to the potential positive or negative effects.

  8. Regulation of DNA double-strand break repair pathway choice

    Institute of Scientific and Technical Information of China (English)

    Meena Shrivastav; Leyma P De Haro; Jac A Nickoloff

    2008-01-01

    DNA double-strand breaks (DSBs) are critical lesions that can result in cell death or a wide variety of genetic alterations including large- or small-scale deletions, loss of heterozygosity, translocations, and chromosome loss. DSBs are repaired by non-homologous end-joining (NHEJ) and homologous recombination (HR), and defects in these pathways cause genome instability and promote tumorigenesis. DSBs arise from endogenous sources includ-ing reactive oxygen species generated during cellular metabolism, collapsed replication forks, and nucleases, and from exogenous sources including ionizing radiation and chemicals that directly or indirectly damage DNA and are commonly used in cancer therapy. The DSB repair pathways appear to compete for DSBs, but the balance between them differs widely among species, between different cell types of a single species, and during different cell cycle phases of a single cell type. Here we review the regulatory factors that regulate DSB repair by NHEJ and HR in yeast and higher eukaryotes. These factors include regulated expression and phosphorylation of repair proteins, chromatin modulation of repair factor accessibility, and the availability of homologous repair templates. While most DSB repair proteins appear to function exclusively in NHEJ or HR, a number of proteins influence both pathways, including the MRE11/RAD50/NBS1 (XRS2) complex, BRCA1, histone H2AX, PARP-1, RAD18, DNA-dependent protein kinase catalytic subunit (DNA-PKcs), and ATM. DNA-PKcs plays a role in mammalian NHEJ, but it also influences HR through a complex regulatory network that may involve crosstalk with ATM, and the regulation of at least 12 proteins involved in HR that are phosphorylated by DNA-PKcs and/or ATM.

  9. Small-Item Contact Test Method, FY11 Release

    Science.gov (United States)

    2012-07-01

    sections on an item. Often designated in a sampling plan and marked on an item to enable quick reference. • sessile drop : A liquid droplet that is...Full item contamination illustration 25 9. Localized contamination illustration 25 10. Gross sample collection technique for small items 32 Blank...decontaminant performance. contamination set: A specific contamination density, drop volume, and deposition pattern combination used for dose confirmation

  10. Negative affect impairs associative memory but not item memory.

    OpenAIRE

    Bisby, J. A.; Burgess, N.

    2014-01-01

    The formation of associations between items and their context has been proposed to rely on mechanisms distinct from those supporting memory for a single item. Although emotional experiences can profoundly affect memory, our understanding of how it interacts with different aspects of memory remains unclear. We performed three experiments to examine the effects of emotion on memory for items and their associations. By presenting neutral and negative items with background contexts, Experiment 1 ...

  11. Dorsal variant blister aneurysm repair.

    Science.gov (United States)

    Couldwell, William T; Chamoun, Roukoz

    2012-01-01

    Dorsal variant proximal carotid blister aneurysms are treacherous lesions to manage. It is important to recognize this variant on preoperative angiographic imaging, in anticipation of surgical strategies for their treatment. Strategies include trapping the involved segment and revascularization if necessary. Other options include repair of the aneurysm rupture site directly. Given that these are not true berry aneurysms, repair of the rupture site involves wrapping or clip-grafting techniques. The case presented here was a young woman with a subarachnoid hemorrhage from a ruptured dorsal variant blister aneurysm. The technique used is demonstrated in the video and is a modified clip-wrap technique using woven polyester graft material. The patient was given aspirin preoperatively as preparation for the clip-wrap technique. It is the authors' current protocol to attempt a direct repair with clip-wrapping and leaving artery sacrifice with or without bypass as a salvage therapy if direct repair is not possible. Assessment of vessel patency after repair is performed by intraoperative Doppler and indocyanine green angiography. Intraoperative somatosensory and motor evoked potential monitoring is performed in all cases. The video can be found here: http://youtu.be/crUreWGQdGo.

  12. Recommendations for Enabling Manual Component Level Electronic Repair for Future Space Missions

    Science.gov (United States)

    Struk, Peter M.; Easton, John W.; Funk, Gregory P.; Latta, Gary S.; Ganster, Andrew W.; Estes, Brett E.

    2011-01-01

    Long duration missions to the Moon and Mars pose a number of challenges to mission designers, controllers, and the crews. Among these challenges are planning for corrective maintenance actions which often require a repair. Current repair strategies on the International Space Station (ISS) rely primarily on the use of Orbital Replacement Units (ORUs), where a faulty unit is replaced with a spare, and the faulty unit typically returns to Earth for analysis and possible repair. The strategy of replace to repair has posed challenges even for the ISS program. Repairing faulty hardware at lower levels such as the component level can help maintain system availability in situations where no spares exist and potentially reduce logistic resupply mass.This report provides recommendations to help enable manual replacement of electronics at the component-level for future manned space missions. The recommendations include hardware, tools, containment options, and crew training. The recommendations are based on the work of the Component Level Electronics Assembly Repair (CLEAR) task of the Exploration Technology Development Program from 2006 to 2009. The recommendations are derived based on the experience of two experiments conducted by the CLEAR team aboard the International Space Station as well as a group of experienced Miniature/Microminiature (2M) electronics repair technicians and instructors from the U.S. Navy 2M Project Office. The emphasis of the recommendations is the physical repair. Fault diagnostics and post-repair functional test are discussed in other CLEAR reports.

  13. Curriculum, Translation, and Differential Functioning of Measurement and Geometry Items

    Science.gov (United States)

    Emenogu, Barnabas C.; Childs, Ruth A.

    2005-01-01

    A test item exhibits differential item functioning (DIF) if students with the same ability find it differentially difficult. When the item is administered in French and English, differences in language difficulty and meaning are the most likely explanations. However, curriculum differences may also contribute to DIF. The responses of Ontario…

  14. 41 CFR 101-27.209-1 - GSA stock items.

    Science.gov (United States)

    2010-07-01

    ...-Management of Shelf-Life Materials § 101-27.209-1 GSA stock items. Shelf-life items that meet the criteria... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true GSA stock items. 101-27.209-1 Section 101-27.209-1 Public Contracts and Property Management Federal Property Management...

  15. The Identification of Radex Properties in Objective Test Items.

    Science.gov (United States)

    Seddon, G. M.; And Others

    1981-01-01

    In a Monte Carlo simulation, a methodology was developed to investigate the existence of radex properties among objective test items. In an experiment with items covering four categories of Bloom's cognitive domain taxonomy, the items did not have the factorial properties of a radex with four levels of complexity. (Author/BW)

  16. Effect of Multiple Testing Adjustment in Differential Item Functioning Detection

    Science.gov (United States)

    Kim, Jihye; Oshima, T. C.

    2013-01-01

    In a typical differential item functioning (DIF) analysis, a significance test is conducted for each item. As a test consists of multiple items, such multiple testing may increase the possibility of making a Type I error at least once. The goal of this study was to investigate how to control a Type I error rate and power using adjustment…

  17. Multistage Computerized Adaptive Testing with Uniform Item Exposure

    Science.gov (United States)

    Edwards, Michael C.; Flora, David B.; Thissen, David

    2012-01-01

    This article describes a computerized adaptive test (CAT) based on the uniform item exposure multi-form structure (uMFS). The uMFS is a specialization of the multi-form structure (MFS) idea described by Armstrong, Jones, Berliner, and Pashley (1998). In an MFS CAT, the examinee first responds to a small fixed block of items. The items comprising…

  18. Stochastic Approximation Methods for Latent Regression Item Response Models

    Science.gov (United States)

    von Davier, Matthias; Sinharay, Sandip

    2010-01-01

    This article presents an application of a stochastic approximation expectation maximization (EM) algorithm using a Metropolis-Hastings (MH) sampler to estimate the parameters of an item response latent regression model. Latent regression item response models are extensions of item response theory (IRT) to a latent variable model with covariates…

  19. A method for designing IRT-based item banks

    NARCIS (Netherlands)

    Boekkooi-Timminga, Ellen

    1990-01-01

    Since 1985 several procedures for computerized test construction using linear programing techniques have been described in the literature. To apply these procedures successfully, suitable item banks are needed. The problem of designing item banks based on item response theory (IRT) is addressed. A p

  20. Higher-Order Item Response Models for Hierarchical Latent Traits

    Science.gov (United States)

    Huang, Hung-Yu; Wang, Wen-Chung; Chen, Po-Hsi; Su, Chi-Ming

    2013-01-01

    Many latent traits in the human sciences have a hierarchical structure. This study aimed to develop a new class of higher order item response theory models for hierarchical latent traits that are flexible in accommodating both dichotomous and polytomous items, to estimate both item and person parameters jointly, to allow users to specify…

  1. The Applicability of Interactive Item Templates in Varied Knowledge Types

    Science.gov (United States)

    Koong, Chorng-Shiuh; Wu, Chi-Ying

    2011-01-01

    A well-edited assessment can enhance student's learning motives. Applicability of items, which includes item content and template, plays a crucial role in authoring a good assessment. Templates in discussion contain not only conventional true & false, multiple choice, completion item and short answer but also of those interactive ones. Methods…

  2. DIF Trees: Using Classification Trees to Detect Differential Item Functioning

    Science.gov (United States)

    Vaughn, Brandon K.; Wang, Qiu

    2010-01-01

    A nonparametric tree classification procedure is used to detect differential item functioning for items that are dichotomously scored. Classification trees are shown to be an alternative procedure to detect differential item functioning other than the use of traditional Mantel-Haenszel and logistic regression analysis. A nonparametric…

  3. Guide to good practices for the development of test items

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    While the methodology used in developing test items can vary significantly, to ensure quality examinations, test items should be developed systematically. Test design and development is discussed in the DOE Guide to Good Practices for Design, Development, and Implementation of Examinations. This guide is intended to be a supplement by providing more detailed guidance on the development of specific test items. This guide addresses the development of written examination test items primarily. However, many of the concepts also apply to oral examinations, both in the classroom and on the job. This guide is intended to be used as guidance for the classroom and laboratory instructor or curriculum developer responsible for the construction of individual test items. This document focuses on written test items, but includes information relative to open-reference (open book) examination test items, as well. These test items have been categorized as short-answer, multiple-choice, or essay. Each test item format is described, examples are provided, and a procedure for development is included. The appendices provide examples for writing test items, a test item development form, and examples of various test item formats.

  4. Is the New Item Priority Effect an Experimental Artifact?

    Science.gov (United States)

    Andre, Thomas

    This research was directed at determining whether the new item priority (NIP) effect in free recall was a result of an experimental artifact produced by the joint action of the serial position effect and the randomization of items over trials, or a consequence of a strategy of recalling newer items before older ones. In the experiment, subjects…

  5. The Applicability of Interactive Item Templates in Varied Knowledge Types

    Science.gov (United States)

    Koong, Chorng-Shiuh; Wu, Chi-Ying

    2011-01-01

    A well-edited assessment can enhance student's learning motives. Applicability of items, which includes item content and template, plays a crucial role in authoring a good assessment. Templates in discussion contain not only conventional true & false, multiple choice, completion item and short answer but also of those interactive ones. Methods…

  6. Gating Items: Definition, Significance, and Need for Further Study

    Science.gov (United States)

    Judd, Wallace

    2009-01-01

    Over the past twenty years in performance testing a specific item type with distinguishing characteristics has arisen time and time again. It's been invented independently by dozens of test development teams. And yet this item type is not recognized in the research literature. This article is an invitation to investigate the item type, evaluate…

  7. The Development of Practical Item Analysis Program for Indonesian Teachers

    Science.gov (United States)

    Muhson, Ali; Lestari, Barkah; Supriyanto; Baroroh, Kiromim

    2017-01-01

    Item analysis has essential roles in the learning assessment. The item analysis program is designed to measure student achievement and instructional effectiveness. This study was aimed to develop item-analysis program and verify its feasibility. This study uses a Research and Development (R & D) model. The procedure includes designing and…

  8. A Procedure for Linear Polychotomous Scoring of Test Items

    Science.gov (United States)

    1993-10-01

    associated with the response categories of test items . When tests are scored using these scoring weights, test reliability increases. The new procedure is...program POLY. The example demonstrates how polyweighting can be used to calibrate and score test items drawn from an item bank that is too large to

  9. Primary Science Assessment Item Setters' Misconceptions Concerning Biological Science Concepts

    Science.gov (United States)

    Boo, Hong Kwen

    2007-01-01

    Assessment is an integral and vital part of teaching and learning, providing feedback on progress through the assessment period to both learners and teachers. However, if test items are flawed because of misconceptions held by the question setter, then such test items are invalid as assessment tools. Moreover, such flawed items are also likely to…

  10. Influence of Item Direction on Student Responses in Attitude Assessment.

    Science.gov (United States)

    Campbell, Noma Jo; Grissom, Stephen

    To investigate the effects of wording in attitude test items, a five-point Likert-type rating scale was administered to 173 undergraduate education majors. The test measured attitudes toward college and self, and contained 38 positively-worded items. Thirty-eight negatively-worded items were also written to parallel the positive statements.…

  11. Analysis of Differential Item Functioning in the NAEP History Assessment.

    Science.gov (United States)

    Zwick, Rebecca; Ercikan, Kadriye

    The Mantel-Haenszel approach for investigating differential item functioning (DIF) was applied to U.S. history items that were administered as part of the National Assessment of Educational Progress (NAEP). DIF analyses were based on the responses of 7,743 students in grade 11. On some items, Blacks, Hispanics, and females performed more poorly…

  12. 41 CFR 101-28.306-6 - Sensitive items.

    Science.gov (United States)

    2010-07-01

    ... for embarrassment of GSA and customer agencies, the level of customer complaints, and control as an accountable item of personal property. Each customer activity shall take all appropriate measures necessary to... 28.3-Customer Supply Centers § 101-28.306-6 Sensitive items. Many items stocked by the CSCs may...

  13. Social Desirability Scale Values of Locus of Control Items

    Science.gov (United States)

    Kestenbaum, Joel M.

    1976-01-01

    Subjects rated each item in Rotter's I-E Scale for its social desirability value. Social desirability scale values (SDSV) of paired items were compared with one another. Results indicate that paired items are not similar in their SDSV, thus enabling subjects to respond on the basis of social desirability. (Author/DEP)

  14. 17 CFR 229.1100 - (Item 1100) General.

    Science.gov (United States)

    2010-04-01

    ... AND CONSERVATION ACT OF 1975-REGULATION S-K Asset-Backed Securities (Regulation AB) § 229.1100 (Item... source of various disclosure items and requirements for “asset-backed securities” filings under the... this Regulation AB, including the definition of “asset-backed security,” are set forth in Item 1101. (b...

  15. Item validity of the Myers-Briggs Type Indicator.

    Science.gov (United States)

    Tzeng, O C; Outcalt, D; Boyer, S L; Ware, R; Landis, D

    1984-06-01

    The present study presents a brief summary of four extensive psychometric analyses of the Myers-Briggs Type Indicator (MBTI) items. Positive empirical evidence supports the MBTI item validity. However, several measurement issues on item construction were raised to caution the future users.

  16. The Relative Importance of Persons, Items, Subtests, and Languages to TOEFL Test Variance.

    Science.gov (United States)

    Brown, James Dean

    1999-01-01

    Explored the relative contributions to Test of English as a Foreign Language (TOEFL) score dependability of various numbers of persons, items, subtests, languages, and their various interactions. Sampled 15,000 test takers, 1000 each from 15 different language backgrounds. (Author/VWL)

  17. 77 FR 29564 - Revisions to the Export Administration Regulations: Auxiliary and Miscellaneous Items That No...

    Science.gov (United States)

    2012-05-18

    ..., exporters must furnish information about the item being exported to the consignee and obtain from the... Security 15 CFR Parts 742, 772 and 774 [Docket No. 111229800-2073-01] RIN 0694-AF51 Revisions to the Export... Control List (CCL) in new Export Control Classification Numbers (ECCNs) 0A617, 0B617, 0C617, 0D617,...

  18. A latent trait look at pretest-posttest validation of criterion-referenced test items

    NARCIS (Netherlands)

    van der Linden, Willem J.

    1981-01-01

    Since Cox and Vargas (1966) introduced their pretest-posttest validity index for criterion-referenced test items, a great number of additions and modifications have followed. All are based on the idea of gain scoring; that is, they are computed from the differences between proportions of pretest and

  19. Two-Phase Item Selection Procedure for Flexible Content Balancing in CAT

    Science.gov (United States)

    Cheng, Ying; Chang, Hua-Hua; Yi, Qing

    2007-01-01

    Content balancing is an important issue in the design and implementation of computerized adaptive testing (CAT). Content-balancing techniques that have been applied in fixed content balancing, where the number of items from each content area is fixed, include constrained CAT (CCAT), the modified multinomial model (MMM), modified constrained CAT…

  20. Teaching of direct composite restoration repair in undergraduate dental schools in the United Kingdom and Ireland.

    Science.gov (United States)

    Blum, I R; Lynch, C D; Wilson, N H F

    2012-02-01

    To investigate aspects of the teaching of restoration repair as a minimally invasive alternative to the replacement of defective direct composite restorations in teaching programmes in undergraduate curricula in dental schools in the United Kingdom and Ireland. An online questionnaire which sought information in relation to the current teaching of composite restoration repair was developed and distributed to the 17 established UK and Irish dental schools with undergraduate teaching programmes in Spring 2010. Completed responses were received from all 17 schools (response rate= 100%). Fifteen schools reported that they included teaching of repair techniques for defective direct composite restorations in their programme. Of the two remaining schools, one indicated that it would introduce teaching of repair techniques during the next five years. The most common indication for a composite repair was that of 'tooth substance preservation' (15 schools). The defects in restorations considered appropriate for repair rather than replacement by the largest number of schools included partial loss of restoration (13 schools) and marginal defects (12 schools). The most commonly taught surface treatment when performing a repair was mechanical roughening of the existing composite with removal of the surface layer (14 schools). Thirteen schools taught etching and the application of an adhesive bonding agent to the prepared surfaces, while the most commonly taught material for completing the repair was a hybrid composite resin (12 schools). Popular finishing implements included diamond finishing instruments (13 schools) and finishing discs (11 schools). Not withstanding reluctance amongst general dental practitioners, the teaching of repair of a defective composite restoration, rather than total restoration replacement, is firmly established within UK and Irish dental school programmes. Repair techniques have clear advantages for patients, not least including a minimally invasive

  1. Modeling the induced mutation process in bacterial cells with defects in excision repair system

    Science.gov (United States)

    Bugay, A. N.; Vasilyeva, M. A.; Krasavin, E. A.; Parkhomenko, A. Yu.

    2015-12-01

    A mathematical model of the UV-induced mutation process in Escherichia coli cells with defects in the uvrA and polA genes has been developed. The model describes in detail the reaction kinetics for the excision repair system. The number of mismatches as a result of translesion synthesis is calculated for both wild-type and mutant cells. The effect of temporal modulation of the number of single-stranded DNA during postreplication repair has been predicted. A comparison of effectiveness of different repair systems has been conducted.

  2. Differential PIXE analysis of Mesoamerican jewelry items

    Science.gov (United States)

    Demortier, G.; Ruvalcaba-Sil, J. L.

    1996-09-01

    Gold jewelry items of Mesoamerican origin (from Peru, Colombia, Mexico, etc,…) are usually cast in Tumbaga: a man-made gold-copper-silver alloy containing a large proportion of copper. In order to give the objects a colour close to that of pure gold, ancient Mesoamerican goldsmiths experimented with a procedure to eliminate less noble metals (like copper and silver) from the surface. RBS may be used to identify a possible enrichment in gold in the most external layer of the items but due to the low capability of this technique to separate scattered particles on gold and silver and due to the low Rutherford cross section for α-particles on copper by comparison with those on gold, the determination of the exact depth depletion of copper cannot be easily reached. Differential PIXE is an appropriate method to achieve this goal. It takes the relative X-ray intensities of Cu and Au lines into account. By varying the incident proton energy, this ratio is modified in a completely different way if the sample is homogeneous or exhibits a layered or depth profile structure.

  3. Two Ports Laparoscopic Inguinal Hernia Repair in Children

    Directory of Open Access Journals (Sweden)

    Medhat M. Ibrahim

    2015-01-01

    Full Text Available Introduction. Several laparoscopic treatment techniques were designed for improving the outcome over the last decade. The various techniques differ in their approach to the inguinal internal ring, suturing and knotting techniques, number of ports used in the procedures, and mode of dissection of the hernia sac. Patients and Surgical Technique. 90 children were subjected to surgery and they undergone two-port laparoscopic repair of inguinal hernia in children. Technique feasibility in relation to other modalities of repair was the aim of this work. 90 children including 75 males and 15 females underwent surgery. Hernia in 55 cases was right-sided and in 15 left-sided. Two patients had recurrent hernia following open hernia repair. 70 (77.7% cases were suffering unilateral hernia and 20 (22.2% patients had bilateral hernia. Out of the 20 cases 5 cases were diagnosed by laparoscope (25%. The patients’ median age was 18 months. The mean operative time for unilateral repairs was 15 to 20 minutes and bilateral was 21 to 30 minutes. There was no conversion. The complications were as follows: one case was recurrent right inguinal hernia and the second was stitch sinus. Discussion. The results confirm the safety and efficacy of two ports laparoscopic hernia repair in congenital inguinal hernia in relation to other modalities of treatment.

  4. Sciatic nerve repair using adhesive bonding and a modiifed conduit

    Institute of Scientific and Technical Information of China (English)

    Xiangdang Liang; Hongfei Cai; Yongyu Hao; Geng Sun; Yaoyao Song; Wen Chen

    2014-01-01

    When repairing nerves with adhesives, most researchers place glue directly on the nerve stumps, but this method does not ifx the nerve ends well and allows glue to easily invade the nerve ends. In this study, we established a rat model of completely transected sciatic nerve injury and re-paired it using a modiifed 1 cm-length conduit with inner diameter of 1.5 mm. Each end of the cylindrical conduit contains a short linear channel, while the enclosed central tube protects the nerve ends well. Nerves were repaired with 2-octyl-cyanoacrylate and suture, which complement the function of the modiifed conduit. The results demonstrated that for the same conduit, the av-erage operation time using the adhesive method was much shorter than with the suture method. No signiifcant differences were found between the two groups in sciatic function index, motor evoked potential latency, motor evoked potential amplitude, muscular recovery rate, number of medullated nerve fibers, axon diameter, or medullary sheath thickness. Thus, the adhesive method for repairing nerves using a modiifed conduit is feasible and effective, and reduces the operation time while providing an equivalent repair effect.

  5. Current developments in hernia repair; meshes, adhesives, and tacking.

    Science.gov (United States)

    Powell, Benjamin S; Voeller, Guy R

    2010-10-01

    Open and laparoscopic hernia surgery continues to evolve with new products allowing surgeons multiple choices in treating their patients. The evolution towards tension-free techniques in dealing with hernias requires that today's surgeons know the options available in meshes as well as fixation methods in order to have the best outcomes. In recent years, there has been a rapid expansion in the number of meshes available. Currently, there are numerous uncoated, coated, and biologic meshes in production that can be used in hernia repair. This paper will focus on the latest developments in coated meshes that allow for intra-abdominal placement as well as the different types of biologic meshes and their typical uses. Tacking devices for laparoscopic hernia repair now come in titanium as well as absorbable devices. AbsorbaTack™ (Covidien, Norwalk, CT) and Sorbafix™ (Davol, Warwick, RI) are two of the newest absorbable tacking devices thought to possibly benefit patients with decreased pain and long-term complications as compared with their titanium counterparts. Adhesives continue to be used more and more for hernia repair, especially in inguinal and paraesophageal hernia repairs. Tissucol™/Tisseel™ (Baxter, Deerfield, IL) and Evicel™ (Ethicon, Somerville, NJ) are two types of fibrin glues that are available for use in hernia repair. Practitioners using these biologic adhesives think there is less pain compared with tacking.

  6. IDEAL framework in surgical innovation applied on laparoscopic niche repair.

    Science.gov (United States)

    Nikkels, C; Vervoort, Anke J M W; Mol, Ben Willem; Hehenkamp, Wouter J K; Huirne, Judith A F; Brölmann, Hans A M

    2017-08-01

    The research objective of the current systematic literature review is to classify the laparoscopic niche repair according to the IDEAL framework of 'innovation stages' and to recommend the required research setting to facilitate safe and properly timed implementation of the technique. In doing so, we are also able to evaluate the practical applicability of the IDEAL framework. A systematic search of the available literature on laparoscopic niche repair was performed in PubMed, Embase, and the Wiley/Cochrane library. Articles were classified according to the IDEAL framework and recommendations were given on additional required research before the technique can be safely implemented. Practical applicability of the IDEAL framework was also evaluated. Introduction of laparoscopic niche repair matches Idea (1) and Development (2a), according to the stages of IDEAL framework, although most studies are retrospective and complications have not been registered structurally in a considerable number of the articles. As feasibility and safety have been more or less established and surgery has been further developed we enter stage 2b (Exploration) and need prospective trials preferably comparing the effectiveness of laparoscopic niche repair to expectant management, the current standard care. Available studies were classified with the use of the IDEAL framework, achieving an overall IDEAL stage to be 2a Development. As clinical outcomes, though poorly registered, have been substantially improved, laparoscopic niche repair needs to be carried forward by more advanced study designs. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Mitochondrial DNA repair: a novel therapeutic target for heart failure.

    Science.gov (United States)

    Marín-García, José

    2016-09-01

    Mitochondria play a crucial role in a variety of cellular processes ranging from energy metabolism, generation of reactive oxygen species (ROS) and Ca(2+) handling to stress responses, cell survival and death. Malfunction of the organelle may contribute to the pathogenesis of neuromuscular, cancer, premature aging and cardiovascular diseases (CVD), including myocardial ischemia, cardiomyopathy and heart failure (HF). Mitochondria contain their own genome organized into DNA-protein complexes, called "mitochondrial nucleoids," along with multiprotein machineries, which promote mitochondrial DNA (mtDNA) replication, transcription and repair. Although the mammalian organelle possesses almost all known nuclear DNA repair pathways, including base excision repair, mismatch repair and recombinational repair, the proximity of mtDNA to the main sites of ROS production and the lack of protective histones may result in increased susceptibility to various types of mtDNA damage. These include accumulation of mtDNA point mutations and/or deletions and decreased mtDNA copy number, which will impair mitochondrial function and finally, may lead to CVD including HF.

  8. Electrosleeve process for in-situ nuclear steam generator repair

    Energy Technology Data Exchange (ETDEWEB)

    Barton, R.A. [Ontario Hydro Technologies, Toronto, ON (Canada); Moran, T.E. [Framatome Technologies Inc., Lynchburg, VA (United States); Renaud, E. [Babcock and Wilcox Industries Ltd., Cambridge, ON (Canada)

    1997-07-01

    Degradation of steam generator (SG) tubing by localized corrosion is a widespread problem in the nuclear industry that can lead to costly forced out-ages, unit de-rating, SG replacement or even the permanent shutdown of a reactor. In response to the onset of SG tubing degradation at Ontario Hydro's Pickering Nuclear Generating Station (PNGS) Unit 5, and the determined unsuitability of conventional repair methods (mechanically expanded or welded sleeves) for Alloy 400, an alternative repair technology was developed. Electrosleeve is a non-intrusive, low-temperature process that involves the electrodeposition of a nanocrystalline nickel microalloy forming a continuously bonded, structural layer over the internal diameter of the degraded region. This technology is designed to provide a long-term pressure boundary repair, fully restoring the structural integrity of the damaged region to its original state. This paper describes the Electrosleeve process for SG tubing repair and the unique properties of the advanced sleeve material. The successful installation of Electrosleeves that have been in service for more than three years in Alloy 400 SG tubing at the Pickering-5 CANDU unit, the more recent extension of the technology to Alloy 600 and its demonstration in a U.S. pressurized water reactor (PWR), is presented. A number of PWR operators have requested plant operating technical specification changes to permit Electrosleeve SG tube repair. Licensing of the Electrosleeve by the U.S. Nuclear Regulatory Commission (NRC) is expected imminently. (author)

  9. Ten Items of Integrated Technology Developed by CNPC

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ The technological work of China National Petroleum Corporation (CNPC) was based on the company's general development strategy to become a multinational giant with international competitiveness during the 10th FiveYear Plan Period (2001-2005). The technological efforts were focused on strengthening strategic management of technology to identify the technological development targets, optimizing allocation of technological resources and increasing technological investment to highlight creation of key technology. Aiming at the important and key technologies needed for main business development,CNPC launched 15 technological projects at the State level with a 100 percent completion rate and 379 other projects at the corporate level with a 92.8 percent completion rate. With a number of high-level results achieved, CNPC has developed 10 items of integrated technology.

  10. Performance of Styrene Butadiene Rubber as a Concrete Repair Material in tropical climate

    Science.gov (United States)

    Radhakrishnan, R.; Prakash, V. Syam; Thampan, C. K.; Varma, Prasad

    2012-11-01

    Deterioration of Concrete due to variety of reasons like corrosion of steel, inferior quality of materials as well as workmanship and exposure to aggressive environment like thermal cycling affect the performance or damage a number of Reinforced cement concrete structures. In order to repair these structures for enhancing the service life, number of methods and materials are available. But the degree of success of any repair in concrete depends mainly on the correct choice and the method of application of repair materials. This paper discusses the details of an experimental investigation on the performance of Styrene ñ Butadiene Rubber (SBR) as a concrete repair material in tropical climatic conditions. Resistance to water penetration and tensile cracking are two important performance criteria for any repair material. Cement mortar cubes of mix proportion 1:3 with SBR added at the rate of 20% of the weight of cement, and control specimens without SBR were made. Compressive strength and sorptivity values of the cubes were determined. Shear Bond strength (by slant shear test) and splitting tensile strength of the repaired cylinder specimens of standard dimensions, in which SBR used as a bonding agent were determined. These values were compared with the values obtained for the similar specimens, in which the bonding agent applied was conventional cement slurry. The influence of thermal cycling on the properties of repaired concrete specimens were also studied. A comparison has also been made with the values required to meet the standard specifications of a repair material.

  11. Augmentation of Rotator Cuff Repair With Soft Tissue Scaffolds

    Science.gov (United States)

    Thangarajah, Tanujan; Pendegrass, Catherine J.; Shahbazi, Shirin; Lambert, Simon; Alexander, Susan; Blunn, Gordon W.

    2015-01-01

    Background Tears of the rotator cuff are one of the most common tendon disorders. Treatment often includes surgical repair, but the rate of failure to gain or maintain healing has been reported to be as high as 94%. This has been substantially attributed to the inadequate capacity of tendon to heal once damaged, particularly to bone at the enthesis. A number of strategies have been developed to improve tendon-bone healing, tendon-tendon healing, and tendon regeneration. Scaffolds have received considerable attention for replacement, reconstruction, or reinforcement of tendon defects but may not possess situation-specific or durable mechanical and biological characteristics. Purpose To provide an overview of the biology of tendon-bone healing and the current scaffolds used to augment rotator cuff repairs. Study Design Systematic review; Level of evidence, 4. Methods A preliminary literature search of MEDLINE and Embase databases was performed using the terms rotator cuff scaffolds, rotator cuff augmentation, allografts for rotator cuff repair, xenografts for rotator cuff repair, and synthetic grafts for rotator cuff repair. Results The search identified 438 unique articles. Of these, 214 articles were irrelevant to the topic and were therefore excluded. This left a total of 224 studies that were suitable for analysis. Conclusion A number of novel biomaterials have been developed into biologically and mechanically favorable scaffolds. Few clinical trials have examined their effect on tendon-bone healing in well-designed, long-term follow-up studies with appropriate control groups. While there is still considerable work to be done before scaffolds are introduced into routine clinical practice, there does appear to be a clear indication for their use as an interpositional graft for large and massive retracted rotator cuff tears and when repairing a poor-quality degenerative tendon. PMID:26665095

  12. Implantable Microsystems for Anatomical Rewiring of Cortical Circuitry: A New Approach for Brain Repair

    Science.gov (United States)

    2009-03-01

    reaching, retrieval of small food items, and locomotion demonstrate that deficits persist during the 5-week recovery period following injury. This will...Implantable microsystem; Neuroplasticity ; Rehabilitation; Traumatic brain injury 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER...we have successfully induced TBI in the CFA, sparing the RFA. Behavioral assessments of reaching, retrieval of small food items, and locomotion

  13. Development of an item bank for food parenting practices based on published instruments and reports from Canadian and US parents.

    Science.gov (United States)

    O'Connor, Teresia M; Pham, Truc; Watts, Allison W; Tu, Andrew W; Hughes, Sheryl O; Beauchamp, Mark R; Baranowski, Tom; Mâsse, Louise C

    2016-08-01

    Research to understand how parents influence their children's dietary intake and eating behaviors has expanded in the past decades and a growing number of instruments are available to assess food parenting practices. Unfortunately, there is no consensus on how constructs should be defined or operationalized, making comparison of results across studies difficult. The aim of this study was to develop a food parenting practice item bank with items from published scales and supplement with parenting practices that parents report using. Items from published scales were identified from two published systematic reviews along with an additional systematic review conducted for this study. Parents (n = 135) with children 5-12 years old from the US and Canada, stratified to represent the demographic distribution of each country, were recruited to participate in an online semi-qualitative survey on food parenting. Published items and parent responses were coded using the same framework to reduce the number of items into representative concepts using a binning and winnowing process. The literature contributed 1392 items and parents contributed 1985 items, which were reduced to 262 different food parenting concepts (26% exclusive from literature, 12% exclusive from parents, and 62% represented in both). Food parenting practices related to 'Structure of Food Environment' and 'Behavioral and Educational' were emphasized more by parent responses, while practices related to 'Consistency of Feeding Environment' and 'Emotional Regulation' were more represented among published items. The resulting food parenting item bank should next be calibrated with item response modeling for scientists to use in the future. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Calculating impact factor: how bibliographical classification of journal items affects the impact factor of large and small journals.

    Science.gov (United States)

    Golubic, Rajna; Rudes, Mihael; Kovacic, Natasa; Marusic, Matko; Marusic, Ana

    2008-03-01

    As bibliographical classification of published journal items affects the denominator in this equation, we investigated how the numerator and denominator of the impact factor (IF) equation were generated for representative journals in two categories of the Journal Citation Reports (JCR). We performed a full text search of the 1st-ranked journal in 2004 JCR category "Medicine, General and Internal" (New England Journal of Medicine, NEJM, IF = 38.570) and 61st-ranked journal (Croatian Medical Journal, CMJ, IF = 0.690), 1st-ranked journal in category "Multidisciplinary Sciences" (Nature, IF = 32.182) and journal with a relative rank of CMJ (Anais da Academia Brasileira de Ciencias, AABC, IF = 0.435). Large journals published more items categorized by Web of Science (WoS) as non-research items (editorial material, letters, news, book reviews, bibliographical items, or corrections): 63% out of total 5,193 items in Nature and 81% out of 3,540 items in NEJM, compared with 31% out of 283 items in CMJ and only 2 (2%) out of 126 items in AABC. Some items classified by WoS as non-original contained original research data (9.5% in Nature, 7.2% in NEJM, 13.7% in CMJ and none in AABC). These items received a significant number of citations: 6.9% of total citations in Nature, 14.7% in NEJM and 18.5% in CMJ. IF decreased for all journals when only items presenting original research and citations to them were used for IF calculation. Regardless of the journal's size or discipline, publication of non-original research and its classification by the bibliographical database have an effect on both numerator and denominator of the IF equation.

  15. Defining value through quantity and quality-Chimpanzees (Pan troglodytes) undervalue food quantities when items are broken.

    Science.gov (United States)

    Parrish, Audrey E; Evans, Theodore A; Beran, Michael J

    2015-02-01

    Decision-making largely is influenced by the relative value of choice options, and the value of such options can be determined by a combination of different factors (e.g., the quantity, size, or quality of a stimulus). In this study, we examined the competing influences of quantity (i.e., the number of food items in a set) and quality (i.e., the original state of a food item) of choice items on chimpanzees' food preferences in a two-option natural choice paradigm. In Experiment 1, chimpanzees chose between sets of food items that were either entirely whole or included items that were broken into pieces before being shown to the chimpanzees. Chimpanzees exhibited a bias for whole food items even when such choice options consisted of a smaller overall quantity of food than the sets containing broken items. In Experiment 2, chimpanzees chose between sets of entirely whole food items and sets of initially whole items that were subsequently broken in view of the chimpanzees just before choice time. Chimpanzees continued to exhibit a bias for sets of whole items. In Experiment 3, chimpanzees chose between sets of new food items that were initially discrete but were subsequently transformed into a larger cohesive unit. Here, chimpanzees were biased to choose the discrete sets that retained their original qualitative state rather than toward the cohesive or clumped sets. These results demonstrate that beyond a food set's quantity (i.e., the value dimension that accounts for maximization in terms of caloric intake), other seemingly non-relevant features (i.e., quality in terms of a set's original state) affect how chimpanzees assign value to their choice options.

  16. The Academic Medical Center Linear Disability Score (ALDS) item bank: item response theory analysis in a mixed patient population.

    Science.gov (United States)

    Holman, Rebecca; Weisscher, Nadine; Glas, Cees A W; Dijkgraaf, Marcel G W; Vermeulen, Marinus; de Haan, Rob J; Lindeboom, Robert

    2005-12-29

    Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55%) residents of supported housing, residential care or nursing homes; 235 (23%) patients with chronic pain; 127 (13%) inpatients on a neurology ward following a stroke; and 89 (9%) patients suffering from Parkinson's disease. Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations.

  17. The Academic Medical Center Linear Disability Score (ALDS) item bank: item response theory analysis in a mixed patient population

    Science.gov (United States)

    Holman, Rebecca; Weisscher, Nadine; Glas, Cees AW; Dijkgraaf, Marcel GW; Vermeulen, Marinus; de Haan, Rob J; Lindeboom, Robert

    2005-01-01

    Background Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. Methods This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55%) residents of supported housing, residential care or nursing homes; 235 (23%) patients with chronic pain; 127 (13%) inpatients on a neurology ward following a stroke; and 89 (9%) patients suffering from Parkinson's disease. Results Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. Conclusion The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations. PMID:16381611

  18. The Academic Medical Center Linear Disability Score (ALDS item bank: item response theory analysis in a mixed patient population

    Directory of Open Access Journals (Sweden)

    Vermeulen Marinus

    2005-12-01

    Full Text Available Abstract Background Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ability to perform activities of daily life. This paper examines the measurement properties of the Academic Medical Center linear disability score item bank in a mixed population. Methods This paper uses item response theory to analyse data on 115 of 170 items from a total of 1002 respondents. These were: 551 (55% residents of supported housing, residential care or nursing homes; 235 (23% patients with chronic pain; 127 (13% inpatients on a neurology ward following a stroke; and 89 (9% patients suffering from Parkinson's disease. Results Of the 170 items, 115 were judged to be clinically relevant. Of these 115 items, 77 were retained in the item bank following the item response theory analysis. Of the 38 items that were excluded from the item bank, 24 had either been presented to fewer than 200 respondents or had fewer than 10% or more than 90% of responses in the category 'can carry out'. A further 11 items had different measurement properties for younger and older or for male and female respondents. Finally, 3 items were excluded because the item response theory model did not fit the data. Conclusion The Academic Medical Center linear disability score item bank has promising measurement characteristics for the mixed patient population described in this paper. Further studies will be needed to examine the measurement properties of the item bank in other populations.

  19. The 12-item World Health Organization Disability Assessment Schedule II (WHO-DAS II: a nonparametric item response analysis

    Directory of Open Access Journals (Sweden)

    Fernandez Ana

    2010-05-01

    Full Text Available Abstract Background Previous studies have analyzed the psychometric properties of the World Health Organization Disability Assessment Schedule II (WHO-DAS II using classical omnibus measures of scale quality. These analyses are sample dependent and do not model item responses as a function of the underlying trait level. The main objective of this study was to examine the effectiveness of the WHO-DAS II items and their options in discriminating between changes in the underlying disability level by means of item response analyses. We also explored differential item functioning (DIF in men and women. Methods The participants were 3615 adult general practice patients from 17 regions of Spain, with a first diagnosed major depressive episode. The 12-item WHO-DAS II was administered by the general practitioners during the consultation. We used a non-parametric item response method (Kernel-Smoothing implemented with the TestGraf software to examine the effectiveness of each item (item characteristic curves and their options (option characteristic curves in discriminating between changes in the underliying disability level. We examined composite DIF to know whether women had a higher probability than men of endorsing each item. Results Item response analyses indicated that the twelve items forming the WHO-DAS II perform very well. All items were determined to provide good discrimination across varying standardized levels of the trait. The items also had option characteristic curves that showed good discrimination, given that each increasing option became more likely than the previous as a function of increasing trait level. No gender-related DIF was found on any of the items. Conclusions All WHO-DAS II items were very good at assessing overall disability. Our results supported the appropriateness of the weights assigned to response option categories and showed an absence of gender differences in item functioning.

  20. The role of difficulty and gender in numbers, algebra, geometry and mathematics achievement

    Science.gov (United States)

    Rabab'h, Belal Sadiq Hamed; Veloo, Arsaythamby; Perumal, Selvan

    2015-05-01

    This study aims to identify the role of difficulty and gender in numbers, algebra, geometry and mathematics achievement among secondary schools students in Jordan. The respondent of the study were 337 students from eight public secondary school in Alkoura district by using stratified random sampling. The study comprised of 179 (53%) males and 158 (47%) females students. The mathematics test comprises of 30 items which has eight items for numbers, 14 items for algebra and eight items for geometry. Based on difficulties among male and female students, the findings showed that item 4 (fractions - 0.34) was most difficult for male students and item 6 (square roots - 0.39) for females in numbers. For the algebra, item 11 (inequality - 0.23) was most difficult for male students and item 6 (algebraic expressions - 0.35) for female students. In geometry, item 3 (reflection - 0.34) was most difficult for male students and item 8 (volume - 0.33) for female students. Based on gender differences, female students showed higher achievement in numbers and algebra compare to male students. On the other hand, there was no differences between male and female students achievement in geometry test. This study suggest that teachers need to give more attention on numbers and algebra when teaching mathematics.

  1. Confirmatory Factor Analysis of the M5-50: An Implementation of the International Personality Item Pool Item Set

    Science.gov (United States)

    Socha, Alan; Cooper, Christopher A.; McCord, David M.

    2010-01-01

    Goldberg's International Personality Item Pool (IPIP; Goldberg, 1999) provides researchers with public-domain, free-access personality measurement scales that are proxies of well-established published scales. One of the more commonly used IPIP sets employs 50 items to measure the 5 broad domains of the 5-factor model, with 10 items per factor. The…

  2. Multidimensional CAT Item Selection Methods for Domain Scores and Composite Scores with Item Exposure Control and Content Constraints

    Science.gov (United States)

    Yao, Lihua

    2014-01-01

    The intent of this research was to find an item selection procedure in the multidimensional computer adaptive testing (CAT) framework that yielded higher precision for both the domain and composite abilities, had a higher usage of the item pool, and controlled the exposure rate. Five multidimensional CAT item selection procedures (minimum angle;…

  3. Multidimensional CAT Item Selection Methods for Domain Scores and Composite Scores with Item Exposure Control and Content Constraints

    Science.gov (United States)

    Yao, Lihua

    2014-01-01

    The intent of this research was to find an item selection procedure in the multidimensional computer adaptive testing (CAT) framework that yielded higher precision for both the domain and composite abilities, had a higher usage of the item pool, and controlled the exposure rate. Five multidimensional CAT item selection procedures (minimum angle;…

  4. Do Images Influence Assessment in Anatomy? Exploring the Effect of Images on Item Difficulty and Item Discrimination

    Science.gov (United States)

    Vorstenbosch, Marc A. T. M.; Klaassen, Tim P. F. M.; Kooloos, Jan G. M.; Bolhuis, Sanneke M.; Laan, Roland F. J. M.

    2013-01-01

    Anatomists often use images in assessments and examinations. This study aims to investigate the influence of different types of images on item difficulty and item discrimination in written assessments. A total of 210 of 460 students volunteered for an extra assessment in a gross anatomy course. This assessment contained 39 test items grouped in…

  5. Production, Purification, and Characterization of 15N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements

    Science.gov (United States)

    Jaruga, Pawel; Nelson, Bryant C.; Lowenthal, Mark S.; Jemth, Ann-Sofie; Loseva, Olga; Coskun, Erdem; Helleday, Thomas

    2016-01-01

    Oxidatively induced DNA damage is caused in living organisms by a variety of damaging agents, resulting in the formation of a multiplicity of lesions, which are mutagenic and cytotoxic. Unless repaired by DNA repair mechanisms before DNA replication, DNA lesions can lead to genomic instability, which is one of the hallmarks of cancer. Oxidatively induced DNA damage is mainly repaired by base excision repair pathway with the involvement of a plethora of proteins. Cancer tissues develop greater DNA repair capacity than normal tissues by overexpressing DNA repair proteins. Increased DNA repair in tumors that removes DNA lesions generated by therapeutic agents before they became toxic is a major mechanism in the development of therapy resistance. Evidence suggests that DNA repair capacity may be a predictive biomarker of patient response. Thus, knowledge of DNA–protein expressions in disease-free and cancerous tissues may help predict and guide development of treatments and yield the best therapeutic response. Our laboratory has developed methodologies that use mass spectrometry with isotope dilution for the measurement of expression of DNA repair proteins in human tissues and cultured cells. For this purpose, full-length 15N-labeled analogs of a number of human DNA repair proteins have been produced and purified to be used as internal standards for positive identification and accurate quantification. This chapter describes in detail the protocols of this work. The use of 15N-labeled proteins as internal standards for the measurement of several DNA repair proteins in vivo is also presented. PMID:26791985

  6. The efficacy of link items in the construction of a numeracy achievement scale--from kindergarten to year 6.

    Science.gov (United States)

    Looveer, Juho; Mulligan, Joanne

    2009-01-01

    A large-scale numeracy research project was commissioned by the Australian Government, involving 4732 Australian students from 91 NSW primary schools. Rasch analysis was applied in the construction of a Numeracy Achievement Scale (NAS) in order to measure numeracy growth. Following trialling, a pool of 244 items was developed to assess number, space and measurement concepts. Link items were included in test forms within year levels and across adjacent year levels to enable linking of the forms and the construction of a scale spanning Kindergarten to Year 6 (5 to 13 years of age). However, results from the scaling were not consistent with expectations of increases in student abilities or item difficulties across year levels. Differential item functioning determined the problematic role of link items across year levels. After a different set of items was used for linking test forms, the results were consistent with expectations. A key finding was that items used to link forms must not exhibit differential item functioning across those levels.

  7. Line-item veto may pass this month

    Science.gov (United States)

    U.S. House and Senate Republicans have cleared the way for legislation to give the President the power of a line-item-veto in time for the 1998 budget season.The line-item veto, as proposed, would allow the President to remove from appropriations bills selected appropriations items, new entitlement spending, or narrowly targeted tax breaks. Once a line item is cut from the budget, Congress would have to pass a separate appropriations bill for that individual item; that new, separate bill would then be subject to the traditional Presidential veto.

  8. A generalized item response tree model for psychological assessments.

    Science.gov (United States)

    Jeon, Minjeong; De Boeck, Paul

    2016-09-01

    A new item response theory (IRT) model with a tree structure has been introduced for modeling item response processes with a tree structure. In this paper, we present a generalized item response tree model with a flexible parametric form, dimensionality, and choice of covariates. The utilities of the model are demonstrated with two applications in psychological assessments for investigating Likert scale item responses and for modeling omitted item responses. The proposed model is estimated with the freely available R package flirt (Jeon et al., 2014b).

  9. The Development of Practical Item Analysis Program for Indonesian Teachers

    Directory of Open Access Journals (Sweden)

    Ali Muhson

    2017-04-01

    Full Text Available Item analysis has essential roles in the learning assessment. The item analysis program is designed to measure student achievement and instructional effectiveness. This study was aimed to develop item-analysis program and verify its feasibility. This study uses a Research and Development (R & D model. The procedure includes designing and developing a product, validating, and testing the product. The data were collected through documentations, questionnaires, and interviews. This study successfully developed item analysis program, namely AnBuso. It is developed based on classical test theory (CTT. It was practical and applicable for Indonesian teachers to analyse test items

  10. Inguinal hernia repair

    OpenAIRE

    1998-01-01

    A hernia usually presents as a painful lump in the groin, often associated with a large strain but it may also be asymptomatic and coincidentally discovered on routine examination. The incidence of hernia increases with age but a large number affected are working men and they can be severely disabled by the condition. Inguinal hernia is a common condition and 763 hernia operations were carried out in Government hospitals in Malta and Gozo during 1997.

  11. Item Discrimination and Type I Error in the Detection of Differential Item Functioning

    Science.gov (United States)

    Li, Yanju; Brooks, Gordon P.; Johanson, George A.

    2012-01-01

    In 2009, DeMars stated that when impact exists there will be Type I error inflation, especially with larger sample sizes and larger discrimination parameters for items. One purpose of this study is to present the patterns of Type I error rates using Mantel-Haenszel (MH) and logistic regression (LR) procedures when the mean ability between the…

  12. Item Analysis and Differential Item Functioning of a Brief Conduct Problem Screen

    Science.gov (United States)

    Wu, Johnny; King, Kevin M.; Witkiewitz, Katie; Racz, Sarah Jensen; McMahon, Robert J.

    2012-01-01

    Research has shown that boys display higher levels of childhood conduct problems than girls, and Black children display higher levels than White children, but few studies have tested for scalar equivalence of conduct problems across gender and race. The authors conducted a 2-parameter item response theory (IRT) model to examine item…

  13. An NCME Instructional Module on Item-Fit Statistics for Item Response Theory Models

    Science.gov (United States)

    Ames, Allison J.; Penfield, Randall D.

    2015-01-01

    Drawing valid inferences from item response theory (IRT) models is contingent upon a good fit of the data to the model. Violations of model-data fit have numerous consequences, limiting the usefulness and applicability of the model. This instructional module provides an overview of methods used for evaluating the fit of IRT models. Upon completing…

  14. Number of Compositions and Convolved Fibonacci numbers

    OpenAIRE

    Janjic, Milan

    2010-01-01

    We consider two type of upper Hessenberg matrices which determinants are Fibonacci numbers. Calculating sums of principal minors of the fixed order of the first type leads us to convolved Fibonacci numbers. Some identities for these and for Fibonacci numbers are proved. We also show that numbers of compositions of a natural number with fixed number of ones appear as coefficients of characteristic polynomial of a Hessenberg matrix which determinant is a Fibonacci number. We derive the explicit...

  15. A Note on the Eigensystem of the Covariance Matrix of Dichotomous Guttman Items.

    Science.gov (United States)

    Davis-Stober, Clintin P; Doignon, Jean-Paul; Suck, Reinhard

    2015-01-01

    We consider the covariance matrix for dichotomous Guttman items under a set of uniformity conditions, and obtain closed-form expressions for the eigenvalues and eigenvectors of the matrix. In particular, we describe the eigenvalues and eigenvectors of the matrix in terms of trigonometric functions of the number of items. Our results parallel those of Zwick (1987) for the correlation matrix under the same uniformity conditions. We provide an explanation for certain properties of principal components under Guttman scalability which have been first reported by Guttman (1950).

  16. A modular approach for item response theory modeling with the R package flirt.

    Science.gov (United States)

    Jeon, Minjeong; Rijmen, Frank

    2016-06-01

    The new R package flirt is introduced for flexible item response theory (IRT) modeling of psychological, educational, and behavior assessment data. flirt integrates a generalized linear and nonlinear mixed modeling framework with graphical model theory. The graphical model framework allows for efficient maximum likelihood estimation. The key feature of flirt is its modular approach to facilitate convenient and flexible model specifications. Researchers can construct customized IRT models by simply selecting various modeling modules, such as parametric forms, number of dimensions, item and person covariates, person groups, link functions, etc. In this paper, we describe major features of flirt and provide examples to illustrate how flirt works in practice.

  17. A note on the eigensystem of the covariance matrix of dichotomous Guttman items

    Directory of Open Access Journals (Sweden)

    Clintin P Davis-Stober

    2015-12-01

    Full Text Available We consider the sample covariance matrix for dichotomous Guttman items under a set of uniformity conditions, and obtain closed-form expressions for the eigenvalues and eigenvectors of the matrix. In particular, we describe the eigenvalues and eigenvectors of the matrix in terms of trigonometric functions of the number of items. Our results parallel those of Zwick (1987 for the correlation matrix under the same uniformity conditions. We provide an explanation for certain properties of principal components under Guttman scalability which have been first reported by Guttman (1950.

  18. Multiple Objective Fuzzy Sourcing Problem with Multiple Items in Discount Environments

    OpenAIRE

    Feyzan Arikan

    2015-01-01

    The selection of proper supply sources plays a vital role to maintain companies’ competitiveness. In this study a multiple criteria fuzzy sourcing problem with multiple items in discount environment is considered as a multiple objective mixed integer linear programming problem. Fuzzy parameters are demand level and/or aspiration levels of objectives. Three objective functions are minimization of the total production and ordering costs, the total number of rejected units, and the total number ...

  19. Detecting measurement disturbance effects: the graphical display of item characteristics.

    Science.gov (United States)

    Schumacker, Randall E

    2015-01-01

    Traditional identification of misfitting items in Rasch measurement models have interpreted the Infit and Outfit z standardized statistic. A more recent approach made possible by Winsteps is to specify "group = 0" in the control file and subsequently view the item characteristic curve for each item against the true probability curve. The graphical display reveals whether an item follows the true probability curve or deviates substantially, thus indicating measurement disturbance. Probability of item response and logit ability are easily copied into data vectors in R software then graphed. An example control file, output item data, and subsequent preparation of an overlay graph for misfit items are presented using Winsteps and R software. For comparison purposes the data are also analyzed using a multi-dimensional (MD) mapping procedure.

  20. Feed mechanism and method for feeding minute items

    Science.gov (United States)

    Stringer, Timothy Kent; Yerganian, Simon Scott

    2012-11-06

    A feeding mechanism and method for feeding minute items, such as capacitors, resistors, or solder preforms. The mechanism is adapted to receive a plurality of the randomly-positioned and randomly-oriented extremely small or minute items, and to isolate, orient, and position the items in a specific repeatable pickup location wherefrom they may be removed for use by, for example, a computer-controlled automated assembly machine. The mechanism comprises a sliding shelf adapted to receive and support the items; a wiper arm adapted to achieve a single even layer of the items; and a pushing arm adapted to push the items into the pickup location. The mechanism can be adapted for providing the items with a more exact orientation, and can also be adapted for use in a liquid environment.