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Sample records for rep bill nelson

  1. Marilyn Nelson: Poetic Justice

    Science.gov (United States)

    Pierpont, Katherine

    2006-01-01

    This article features some of the books written by Marilyn Nelson. Here, the author discusses how she has written a children's book of poetry about lynching, entitled "A Wreath for Emmitt Till." The author discusses how her books for children honor and memorialize history-changing African Americans. Among other things, the author discusses some of…

  2. Nelson syndrome: definition and management.

    Science.gov (United States)

    Barber, T M; Adams, E; Wass, J A H

    2014-01-01

    Nelson syndrome is an important complication of treatment with total bilateral adrenalectomy (TBA) for patients with refractory Cushing's disease. Although early cases of Nelson syndrome often presented with the clinical features of large sellar masses, the modern face of Nelson syndrome has changed primarily due to earlier detection (with highly resolved magnetic resonance imaging (MRI) and sensitive ACTH assays) and greater awareness of the condition, resulting in reduced morbidity and mortality. Although lack of administration of neoadjuvant pituitary radiotherapy post-TBA surgery may predict future development of Nelson syndrome, other predictive factors remain controversial. Therefore, Nelson syndrome should be screened for closely and long-term in all patients with a history of Cushing's disease and TBA. The diagnosis of Nelson syndrome remains controversial, and the pathogenesis of this condition is incompletely understood. Current hypotheses include the "released negative feedback" mechansism (residual pituitary corticotropinoma cells are "released" from the negative feedback effects of cortisol following TBA), and the "aggressive corticotropinoma" mechanism (Nelson syndrome is most likely to develop in those patients with refractory treatments - including TBA - for an underlying aggressive corticotropinoma). Effective management of Nelson syndrome with pituitary surgery and radiotherapy is often a challenge. Other therapies (such as Gamma Knife surgery and temozolomide) play an important role and merit further research into their efficacy and placement in the management pathway of Nelson syndrome.

  3. Nelson Textbook of Pediatrics.

    Science.gov (United States)

    Pomerance, Herbert H

    1997-03-01

    The dedication of this volume states:To the physicians and nurses who care for children in many different circumstances throughout the world and who, by their efforts and commitment, make the world a better place for children.I have used the Nelson Textbook of Pediatrics since its third edition. It remains a source of amazement to me, as I witness the evolution of the book and of the knowledge that dictates its scope. From the days when a textbook was written by 1 or 2 authors, we have progressed to the point where this would be impossible. Three editors preside over this volume; they are also counted among the 212 contributors that lend special expertise to the work, continuing the volume as one of the traditions of pediatrics.The tremendous and rapid explosion in the amount of knowledge in pediatrics made a revision of the total material and even of.

  4. 78 FR 75205 - Death of Nelson Mandela

    Science.gov (United States)

    2013-12-10

    ... Documents#0;#0; ] Proclamation 9067 of December 5, 2013 Death of Nelson Mandela By the President of the... dignity--Nelson Mandela is no longer with us, he belongs to the ages. Nelson Mandela achieved more than... world, and the rightness of reconciliation. Through his fierce dignity and unbending will to sacrifice...

  5. NELSON lung cancer screening study

    NARCIS (Netherlands)

    Y. Zhao (Yingru); X. Xie (Xueqian); H.J. de Koning (Harry); W.P. Mali (Willem); R. Vliegenthart (Rozemarijn); M. Oudkerk (Matthijs)

    2011-01-01

    textabstractThe Dutch-Belgian Randomized Lung Cancer Screening Trial (Dutch acronym: NELSON study) was designed to investigate whether screening for lung cancer by low-dose multidetector computed tomography (CT) in high-risk subjects will lead to a decrease in 10-year lung cancer mortality of at

  6. Nelson River and Hudson Bay

    Science.gov (United States)

    2002-01-01

    Rivers that empty into large bodies of water can have a significant impact on the thawing of nearshore winter ice. This true-color Moderate Resolution Imaging Spectroradiometer (MODIS) image from May 18, 2001, shows the Nelson River emptying spring runoff from the Manitoba province to the south into the southwestern corner of Canada's Hudson Bay. The warmer waters from more southern latitudes hasten melting of ice near the shore, though some still remained, perhaps because in shallow coastal waters, the ice could have been anchored to the bottom. High volumes of sediment in the runoff turned the inflow brown, and the rim of the retreating ice has taken on a dirty appearance even far to the east of the river's entrance into the Bay. The sediment would have further hastened the melting of the ice because its darker color would have absorbed more solar radiation than cleaner, whiter ice. Image courtesy Jacques Descloitres, MODIS Land Rapid Response Team at NASA GSFC

  7. Relativism: Protagoras and Nelson Goodman

    Directory of Open Access Journals (Sweden)

    Esmaeil Saadati Khamseh

    2015-12-01

    Full Text Available Discussion of the many faces of relativism occupies a highly prominent place in the epistemological literature. Protagoras in ancient Greece and Nelson Goodman in the modern period are two most notable proponent of relativism. In the present article, I discuss and explain relativistic approaches of this two important relativist. I will first briefly define and review some faces of relativism. Then I will discuss and elaborate Protagorean or true-for-me relativism and Goodman’s radical relativism in turn. I will argue that there are crucial difficulties in Protagorean and radical relativism, and that these difficulties, as the realist philosophers insist, make these two faces of relativism be undefensible. No doubt, these two shapes of relativism have paved the way for anti-realism. In the end, it will appear that Goodman’s radical relativism and so the theory of worldmaking, like Protagorean relativism, suffers from a fatal flaw: the flaw of self-refuting.

  8. Nelson syndrome: historical perspectives and current concepts.

    Science.gov (United States)

    Hornyak, Mark; Weiss, Martin H; Nelson, Don H; Couldwell, William T

    2007-01-01

    The appearance of an adrenocorticotropic hormone (ACTH)-producing tumor after bilateral adrenalectomy for Cushing disease was first described by Nelson in 1958. The syndrome that now bears his name was characterized by hyperpigmentation, a sellar mass, and increased plasma ACTH levels. The treatment of Cushing disease has changed drastically since the 1950s, when the choice was adrenalectomy. Thus, the occurrence, diagnosis, and treatment of Nelson syndrome have changed as well. In the modern era of high-resolution neuroimaging, transsphenoidal microneurosurgery, and stereotactic radiosurgery, Nelson syndrome has become a rare entity. The authors describe the history of the diagnosis and treatment of Nelson syndrome. In light of the changes described, the authors believe this disease must be reevaluated in the contemporary era and a modern paradigm adopted.

  9. MRI versus CT in the diagnosis of Nelson`s syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Kasperlik-Zaluska, A. [Department of Endocrinology, Centre of Postgraduate Medical Education, Ceglowska 80, 01-809 Warsaw (Poland); Walecki, J. [Imaging Department, Centre of Postgraduate Medical Education, Warsaw (Poland); Brzezinski, J. [Imaging Department, Centre of Postgraduate Medical Education, Warsaw (Poland); Jeske, W. [Department of Endocrinology, Centre of Postgraduate Medical Education, Ceglowska 80, 01-809 Warsaw (Poland); Migdalska, B. [Department of Endocrinology, Centre of Postgraduate Medical Education, Ceglowska 80, 01-809 Warsaw (Poland); Bonicki, W. [Department of Neurosurgery, Academy of Medicine, Warsaw (Poland); Brzezinska, A. [Department of Endocrinology, Centre of Postgraduate Medical Education, Ceglowska 80, 01-809 Warsaw (Poland); Makowska, A. [Department of Endocrinology, Centre of Postgraduate Medical Education, Ceglowska 80, 01-809 Warsaw (Poland)

    1997-02-01

    The purpose of the study was to evaluate the utility of MRI and CT in the diagnosis of Nelson`s syndrome, i. e. pituitary tumours in patients bilaterally adrenalectomized for Cushing`s disease. Thirteen patients, followed up for 5-29 years after adrenalectomy, were studied. In 6 of them CT and MRI revealed no changes in the pituitary gland. In the remaining 7 patients only three CT scans were suggestive of a pituitary adenoma. MRI studies with administration of gadodiamide confirmed the CT diagnosis of Nelson`s tumour in 3 patients and disclosed microadenomas in a further 4 patients. Neurosurgical treatment in 4 patients confirmed the MRI findings. Additionally CT and MRI examinations were performed in 5 patients suspected of a recurrent Nelson`s tumour 3-11 years after neurosurgery. MRI visualized recurrent adenomas in 3 patients that were not well seen by CT scans. In our experience MRI was more effective than CT in the diagnosis of Nelson`s syndrome. (orig.). With 3 figs., 1 tab.

  10. República Argentina

    OpenAIRE

    Centro de Estudios Sudamericanos

    2008-01-01

    El sistema de gobierno en la Argentina adopta la forma representativa, republicana y federal (Constitución Nacional, art. 1º).Por su extensión -que corresponden al Continente Americano; al Continente Antártico (incluyendo las Islas Orcadas del Sur) y las islas australes (Georgias del Sur y Sandwich del Sur)- ocupa el cuarto lugar entre los países americanos (después de Canadá, Estados Unidos de América y la República Federativa del Brasil) y el séptimo a nivel mundial. Con una población de má...

  11. República Argentina

    OpenAIRE

    Centro de Estudios Sudamericanos (CENSUD)

    2008-01-01

    El sistema de gobierno en la Argentina adopta la forma representativa, republicana y federal (Constitución Nacional, art. 1º).Por su extensión -que corresponden al Continente Americano; al Continente Antártico (incluyendo las Islas Orcadas del Sur) y las islas australes (Georgias del Sur y Sandwich del Sur)- ocupa el cuarto lugar entre los países americanos (después de Canadá, Estados Unidos de América y la República Federativa del Brasil) y el séptimo a nivel mundial. Con una población de má...

  12. Bill Maurer

    National Research Council Canada - National Science Library

    Lauren Tooker

    2014-01-01

    Professor Bill Maurer is a renowned cultural anthropologist who conducts research on law, property, money and finance, focusing on the technological infrastructures and social relations of exchange and payment...

  13. Challenges for the Nelson-Barr Mechanism

    CERN Document Server

    Dine, Michael

    2015-01-01

    Solutions to strong CP based on chiral structure have been subject to the most careful scrutiny and critique. Basic theoretical issues include hierarchy and fine-tuning problems, quality and genericity of symmetries, and compatibility with solutions to the electroweak hierarchy problem. We study the similar set of challenges for solutions to strong CP based on spontaneous CP violation and the Nelson-Barr mechanism. Some of our observations have appeared in the literature previously, and others are new; our purpose is to collect and analyze the issues as a whole and provide an assessment of the most plausible settings for the Nelson-Barr solution.

  14. Philosophical Remarks on Nelson Mandela's Education Legacy

    Science.gov (United States)

    Waghid, Yusef

    2014-01-01

    In this article, I reflect on Nelson Mandela's (Madiba, the clan name of Mandela) education legacy. I argue that Madiba's education legacy is constituted by three interrelated aspects: firstly, an education for non-violence guided by deliberation, compassion and reconciliation; secondly, education as responsibility towards the Other; and thirdly,…

  15. Bayesian semiparametric dynamic Nelson-Siegel model

    NARCIS (Netherlands)

    C. Cakmakli

    2011-01-01

    This paper proposes the Bayesian semiparametric dynamic Nelson-Siegel model where the density of the yield curve factors and thereby the density of the yields are estimated along with other model parameters. This is accomplished by modeling the error distributions of the factors according to a Diric

  16. RepA and RepB exert plasmid incompatibility repressing the transcription of the repABC operon.

    Science.gov (United States)

    Pérez-Oseguera, Angeles; Cevallos, Miguel A

    2013-11-01

    Rhizobium etli CFN42 has a multipartite genome composed of one chromosome and six large plasmids with low copy numbers, all belonging to the repABC plasmid family. All elements essential for replication and segregation of these plasmids are encoded within the repABC operon. RepA and RepB direct plasmid segregation and are involved in the transcriptional regulation of the operon, and RepC is the initiator protein of the plasmid. Here we show that in addition to RepA (repressor) and RepB (corepressor), full transcriptional repression of the operon located in the symbiotic plasmid (pRetCFN42d) of this strain requires parS, the centromere-like sequence, and the operator sequence. However, the co-expression of RepA and RepB is sufficient to induce the displacement of the parental plasmid. RepA is a Walker-type ATPase that self associates in vivo and in vitro and binds specifically to the operator region in its RepA-ADP form. In contrast, RepA-ATP is capable of binding to non-specific DNA. RepA and RepB form high molecular weight DNA-protein complexes in the presence of ATP and ADP. RepA carrying ATP-pocket motif mutations induce full repression of the repABC operon without the participation of RepB and parS. These mutants specifically bind the operator sequence in their ATP or ADP bound forms. In addition, their expression in trans exerts plasmid incompatibility against the parental plasmid. RepA and RepB expressed in trans induce plasmid incompatibility because of their ability to repress the repABC operon and not only by their capacity to distort the plasmid segregation process.

  17. Nelson Mandela and the Power of Ubuntu

    Directory of Open Access Journals (Sweden)

    Claire E. Oppenheim

    2012-04-01

    Full Text Available Nelson Mandela dedicated his life to fighting for the freedom of his South African kin of all colors against the institution of apartheid. He spent twenty-seven years fighting from within prison, only gaining his freedom when his fellow South Africans could claim it as well. This article demonstrates how his faith, his spiritual development and his noble purpose can be conceptualized through the lens of Ubuntu: the African ethic of community, unity, humanity and harmony.

  18. Bill Maurer

    Directory of Open Access Journals (Sweden)

    Lauren Tooker

    2014-10-01

    Full Text Available Professor Bill Maurer is a renowned cultural anthropologist who conducts research on law, property, money and finance, focusing on the technological infrastructures and social relations of exchange and payment. Professor Maurer graduated from Stanford University in 1994 with a PhD in Anthropology. He moved to UC Irvine in 1996 as Assistant Professor, going on to become Chair of UC Irvine’s Department of Anthropology (2005-2011 and Associate Dean for Research and Graduate Studies in the Social Sciences (2011-2013. In July 2013 he assumed his current role as Dean of UC Irvine’s School of Social Sciences. Professor Maurer has published on topics ranging from offshore financial services to mobile phone-enabled money transfers, Islamic finance, alternative currencies, and the future of money. He is founding director of the Institute for Money, Technology and Financial Inclusion, funded by the Bill and Melinda Gates Foundation, and was the founding co-director of the Intel Science and Technology Center in Social Computing. He is the editor of six collections, as well as the author of Recharting the Caribbean: Land, Law and Citizenship in the British Virgin Islands (1997, Pious Property: Islamic Mortgages in the United States (2006, and Mutual Life, Limited: Islamic Banking, Alternative Currencies, Lateral Reason (2005. The latter received the Victor Turner Prize in 2005. Professor Maurer visited the University of Warwick in September 2014 under the auspices of Warwick’s Global Governance GRP.

  19. Nelson's syndrome in pregnancy

    Energy Technology Data Exchange (ETDEWEB)

    Surrey, E.S.; Chang, R.J.

    1985-10-01

    The therapeutic considerations in the management of Nelson's syndrome in a 29 year old primigravida are described. CT scans revealed a 2-cm solid pituitary lesion with suprasellar extension and chiasmatic encroachment. A transsphenoidal hypophysectomy was performed to remove a eosinophilic pituitary adenoma. The patient's symptoms improved following surgery. Fetal growth was followed by ultrasound and a female infant was delivered by cesarean section. Follow-up CT scan 2 weeks after delivery revealed no evidence of tumor recurrence.

  20. Understanding your hospital bill

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000881.htm Understanding your hospital bill To use the sharing features on this ... help you save money. Charges Listed on Your Hospital Bill A hospital bill will list the major ...

  1. Treatment of Nelson's syndrome with temozolomide.

    Science.gov (United States)

    Moyes, V J; Alusi, G; Sabin, H I; Evanson, J; Berney, D M; Kovacs, K; Monson, J P; Plowman, P N; Drake, W M

    2009-01-01

    A 64-year-old woman was previously treated for Cushing's disease with trans-sphenoidal surgery, external beam radiotherapy and bilateral adrenalectomy. Progression of an aggressive corticotroph adenoma was evident 3 years post-adrenalectomy; involvement of the clivus was treated with surgery and gamma knife radiosurgery. Tumour spread through the skull base, occiput and left ear with persistent facial pain and left ear discharge; progression continued despite second gamma knife treatment. ACTH levels peaked at 2472 and 2265 pmol/l pre- and post-hydrocortisone respectively. Treatment with temozolomide resulted in a significant improvement in symptoms, a reduction of plasma ACTH to 389 pmol/l and regression of tumour on magnetic resonance imaging scan after four cycles of treatment. We propose that temozolomide is an effective and well-tolerated therapeutic tool for the treatment of Nelson's syndrome and a useful addition to the range of therapies available to treat this condition.

  2. Mass Renormalization in the Nelson Model

    Directory of Open Access Journals (Sweden)

    Fumio Hiroshima

    2017-01-01

    Full Text Available The asymptotic behavior of the effective mass meff(Λ of the so-called Nelson model in quantum field theory is considered, where Λ is an ultraviolet cutoff parameter of the model. Let m be the bare mass of the model. It is shown that for sufficiently small coupling constant α of the model, meff(Λ/m can be expanded as meff(Λ/m=1+∑n=1∞an(Λα2n. A physical folklore is that an(Λ=O(logΛ(n-1 as Λ→∞. It is rigorously shown that 0

  3. Nelson`s syndrome associated with a somatic frame shift mutation in the glucocorticoid recepter gene

    Energy Technology Data Exchange (ETDEWEB)

    Karl, M.; Stratakis, C.A.; Chrousos, G.P.; Katz, D.A.; Ali, I.U.; Oldfield, E.H. [National Inst. of Neurological Disorders and Stroke, Bethesda, MD (United States)] [and others

    1996-01-01

    Nelson`s syndrome is the appearance and/or progression of ACTH-secreting pituitary macroadenomas in patients who had previously undergone bilateral adrenalectomy for Cushing`s disease. Extremely high plasma ACTH levels and aggressive neoplastic growth might be explained by the lack of appropriate glucocorticoid negative feedback due to defective glucocorticoid signal transduction. To study the glucocorticoid receptor (GR) gene in Nelson`s syndrome, DNA was extracted from pituitary adenomas and leukocytes of four patients with this condition and amplified by PCR for direct sequence analysis. In one of the tumors, a heterozygous mutation, consisting of an insertion of a thymine between complementary DNA nucleotides 1188 and 1189, was found in exon 2. This frame-shift mutation led to premature termination at amino acid residue 366 of the world-type coding sequence, excluding the expression of a functioning receptor protein from the defective allele. The mutation was not detected in the sequence of the GR gene in the patient`s leukocyte DNA, indicating a somatic origin. By lowering the receptor number in tumorous cells, this defect might have caused local resistance to negative glucocorticoid feedback similar to that caused by the presence of a null allele in a kindred with the generalized glucocorticoid resistance syndrome. P53 protein accumulation, previously reported in 60% of corticotropinomas, could not be detected in any of the four pituitary tumors examined by immunohistochemistry. We suggest that a somatic GR defect might have played a pathophysiological role in the tumorigenesis of the corticotropinoma bearing this mutation. 35 refs., 3 figs., 1 tab.

  4. Utshitsja drug u druga / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2005-01-01

    Haridus- ja teadusminister Mailis Reps uuendustest koolide õppekavades, õpetajate täienduskoolituse tähtsusest, kutsehariduse arengust, tasuta toitlustamisest põhi- ja kutsekoolides, õpetajate palkadest

  5. Utshitsja drug u druga / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2005-01-01

    Haridus- ja teadusminister Mailis Reps uuendustest koolide õppekavades, õpetajate täienduskoolituse tähtsusest, kutsehariduse arengust, tasuta toitlustamisest põhi- ja kutsekoolides, õpetajate palkadest

  6. Aproximación a la arquitectura de Paul Nelson

    OpenAIRE

    Escalonilla, Javier

    2010-01-01

    Paul Nelson (Chicago 1895- Marsella 1979), aviador, pintor, arquitecto. Del racionalismo francés a la marca americana. Vivir, habitar, construir. La Maison Suspendue, una casa inexistente para habitar el aire.

  7. David Nelson, MD, MPH | Division of Cancer Prevention

    Science.gov (United States)

    Dr. David E Nelson is the Director of the Cancer Prevention Fellowship Program (CPFP) Branch in the National Cancer Institute's Division of Cancer Prevention. The CPFP is an internationally renowned postdoctoral program designed to train early career scientific researchers and leaders in the field of cancer prevention. Dr. Nelson came to the CPFP in 2008 after working at the Centers for Disease Control and Prevention in Atlanta for many years. |

  8. República del Paraguay

    OpenAIRE

    Centro de Estudios Sudamericanos

    2008-01-01

    La República del Paraguay adopta para su gobierno la democracia representativa, participativa y pluralista, fundada en el reconocimiento de la dignidad humana. Está ubicado en el corazón de América del Sur, dividido por el Río Paraguay en dos regiones, Oriental y Occidental o Chaco. Es un país mediterráneo, ya que no posee costas marítimas, así como lo es su vecino Bolivia, pero riegan sus costas dos ríos importantes, el Paraguay y el Paraná que desembocan en el Río de la Plata y que son util...

  9. Analyzing Oil Futures with a Dynamic Nelson-Siegel Model

    DEFF Research Database (Denmark)

    Hansen, Niels Strange; Lunde, Asger

    In this paper we are interested in the term structure of futures contracts on oil. The objective is to specify a relatively parsimonious model which explains data well and performs well in a real time out of sample forecasting. The dynamic Nelson-Siegel model is normally used to analyze and forec......In this paper we are interested in the term structure of futures contracts on oil. The objective is to specify a relatively parsimonious model which explains data well and performs well in a real time out of sample forecasting. The dynamic Nelson-Siegel model is normally used to analyze...... and forecast interest rates of different maturities. The structure of oil futures resembles the structure of interest rates and this motivates the use of this model for our purposes. The data set is vast and the dynamic Nelson-Siegel model allows for a significant dimension reduction by introducing three...

  10. Minister Reps valetas kantslerit vallandades / Urmo Soonvald

    Index Scriptorium Estoniae

    Soonvald, Urmo, 1973-

    2006-01-01

    Kuigi haridus- ja teadusminister Mailis Reps ütles juulikuus, et ta loodab ministeeriumi kantsleri Jaan Kallasega kokkuleppele jõuda, oli tal selleks ajaks juba uus kantsler välja valitud, väidab autor

  11. República Federativa de Brasil

    OpenAIRE

    Centro de Estudios Sudamericanos

    2007-01-01

    Brasil, es un Estado organizado como una república federal, con una forma de gobierno democrática representativa y participativa. La república está organizada en 27 estados (26 más el Distrito Federal donde está ubicada la capital nacional, Brasilia). (Párrafo extraído del texto a modo de resumen) Instituto de Relaciones Internacionales (IRI)

  12. Use and Misuse of the Nelson-Denny Reading Test.

    Science.gov (United States)

    Meter, B. Jean Van; Herrmann, Beth Ann

    1987-01-01

    Reviews the strengths and weaknesses of the Nelson-Denny Reading Test (NDRT) and compares the use and misuse of the test as revealed through published surveys. Finds problems in the use of the NDRT to diagnose the specific reading needs and deficiencies of low-achieving students and to measure individual growth. (CBC)

  13. Examining the Nelson-Siegel Class of Term Structure Models

    NARCIS (Netherlands)

    M.D. de Pooter (Michiel)

    2007-01-01

    textabstractIn this paper I examine various extensions of the Nelson and Siegel (1987) model with the purpose of fitting and forecasting the term structure of interest rates. As expected, I find that using more flexible models leads to a better in-sample fit of the term structure. However, I show th

  14. Nelson ja Rodney - inglaste erandlikud lahingulaevad / Sander Kingsepp

    Index Scriptorium Estoniae

    Kingsepp, Sander

    2006-01-01

    1922. aastal Washingtonis alla kirjutatud mereväerelvastuse lepe läks ajalukku äpardunud katsena võidurelvastamisele piir panna. Leppega ühinenud riigid hakkasid ilmutama veidra välimusega sõjalaevu, mille seas olid aukohal Briti alused "Nelson" ja "Rodney"

  15. John Nelson Darby: His Contributions to Evangelical Christian Higher Education

    Science.gov (United States)

    Sutherland, Winston Terrance

    2010-01-01

    The study reported in this article focused on the contributions of John Nelson Derby to biblical hermeneutics and contemporary eschatological thought. Darby continues to exert a great influence on Christianity, particularly conservative evangelical Christianity. This research provides a discussion of Darby's contributions to contemporary…

  16. Corner Office Interview: SirsiDynix's Rautenstrauch and Nelson

    Science.gov (United States)

    Rapp, David; Fialkoff, Francine

    2010-01-01

    This article presents an interview with SirsiDynix CEO Gary M. Rautenstrauch and newly appointed VP of library relations Berit Nelson about some of the issues that have been roiling the ILS world and the company itself, among them the recent consolidation of SirsiDynix's offices, customer service, the state of library budgets, the rise of ebooks…

  17. John Nelson Darby: Scholarship that Influenced the Bible College Movement

    Science.gov (United States)

    Sutherland, Winston Terrance

    2010-01-01

    The study reported in this article focused on the scholastic life of John Nelson Darby and his contributions to the Bible college movement. Darby continues to exert a great influence on Christianity, particularly conservative evangelical Christianity. This research provides a discussion of the forces that conspired to shape the direction of…

  18. A Good Time: A Conversation with C. Michael Nelson

    Science.gov (United States)

    Zabel, Robert; Kaff, Marilyn; Teagarden, Jim

    2015-01-01

    C. Michael Nelson began his special education career as a teacher of adolescents with learning and behavior disorders. He has worked as a child psychologist and as a professor with the Department of Special Education and Rehabilitation Counseling at the University of Kentucky. He coordinated the graduate Personnel Preparation Program for Teachers…

  19. Nelson ja Rodney - inglaste erandlikud lahingulaevad / Sander Kingsepp

    Index Scriptorium Estoniae

    Kingsepp, Sander

    2006-01-01

    1922. aastal Washingtonis alla kirjutatud mereväerelvastuse lepe läks ajalukku äpardunud katsena võidurelvastamisele piir panna. Leppega ühinenud riigid hakkasid ilmutama veidra välimusega sõjalaevu, mille seas olid aukohal Briti alused "Nelson" ja "Rodney"

  20. Consumer Product Safety Bills.

    Science.gov (United States)

    American Enterprise Inst. for Public Policy Research, Washington, DC.

    This legislative analysis of the actions of the 92nd Congress concerning consumer product safety bills, current as of March 20, 1972, presents briefly the background of Congressional investigations in this area. Describing in detail four major bills which focus on the establishment of an independent government agency regulating consumer products…

  1. República del Perú

    OpenAIRE

    Centro de Estudios Sudamericanos

    2006-01-01

    La República del Perú es un Estado organizado como una república unitaria, con una forma de gobierno democrática representativa y participativa. La población es de 25.662 millones de habitantes, siendo el 47% de origen indígena. La población urbana representa el 72,3% y la rural el 27,7% de la población total. Las mayores concentraciones de población se encuentran en la franja costera y en algunos núcleos urbanos de la sierra andina. La densidad poblacional es de 19 habitantes por k...

  2. William James (Bill) Treadwell

    National Research Council Canada - National Science Library

    2012-01-01

      Bill was born into a farming family in Mataroa near Taihape, in 1928, and was educated at Ruanui School, St Georges School and Wanganui Collegiate, where he played cricket and rugby, to First XI and First XV levels...

  3. Creativity with Bill Moyers.

    Science.gov (United States)

    Marantz, Paula

    1982-01-01

    Outlines the purpose and content of the television series "Creativity with Bill Moyers." Programs explore creativity by investigating the way artists and other innovators express themselves in their work and in solving problems. (AM)

  4. Gamma knife radiosurgery for Cushing's disease and Nelson's syndrome.

    Science.gov (United States)

    Marek, Josef; Ježková, Jana; Hána, Václav; Kršek, Michal; Liščák, Roman; Vladyka, Vilibald; Pecen, Ladislav

    2015-06-01

    This paper presents our 18 years of experience in treating ACTH secreting adenomas (Cushing's disease and Nelson's syndrome) using the Leksell gamma knife (LGK) irradiation. Twenty-six patients with Cushing's disease were followed-up after LGK irradiation for 48-216 months (median 78 months). Seventeen patients had undergone previous surgery, in nine patients LGK irradiation was the primary therapy. Furthermore, 14 patients with Nelson's syndrome were followed-up for 30-204 months (median 144 months). LGK treatment resulted in hormonal normalization in 80.7 % of patients with Cushing's disease. Time to normalization was 6-54 months (median 30 months). The volume of the adenoma decreased in 92.3% (in 30.7% disappeared completely). There was no recurrence of the disease. In all 14 patients with Nelson's syndrome ACTH levels decreased (in two patients fully normalized) their ACTH levels. When checked up 5-10 years after irradiation regrowth of the adenoma was only detected in one patient (9.1%), in 27.3% adenoma volume remained unchanged, in 45.4% adenoma volume decreased and in 18.2% adenoma completely disappeared. Hypopituitarism did not develop in any patient where the critical dose to the pituitary and distal infundibulum was respected. LGK radiation represents an effective and well-tolerated option for the treatment of patients with Cushing's disease after unsuccessful surgery and may be valuable even as a primary treatment in patients who are not suitable for, or refuse, surgery. In the case of Nelson's syndrome it is possible to impede tumorous growth and control the size of the adenoma in almost all patients.

  5. Nelson Rodrigues : ficção e homoerotismo.

    OpenAIRE

    Souza Júnior, José Luiz Foureaux de; Alves, Gustavo Moreira

    2014-01-01

    Este trabalho faz uma introdução ao homoerotismo. Em seguida, o homoerotismo é levantado como hipótese no conto “A desconhecida”, da coluna A vida como ela é..., de Nelson Rodrigues. __________________________________________________________________________________________________________________ ABSTRACT: This work makes an introduction to the homoeroticism. Then the homoeroticism is raised as a hypothesis in the short-story “A desconhecida”, from column A vida como ela é..., by Nel...

  6. The replication origin of a repABC plasmid

    Directory of Open Access Journals (Sweden)

    Cevallos Miguel A

    2011-06-01

    Full Text Available Abstract Background repABC operons are present on large, low copy-number plasmids and on some secondary chromosomes in at least 19 α-proteobacterial genera, and are responsible for the replication and segregation properties of these replicons. These operons consist, with some variations, of three genes: repA, repB, and repC. RepA and RepB are involved in plasmid partitioning and in the negative regulation of their own transcription, and RepC is the limiting factor for replication. An antisense RNA encoded between the repB-repC genes modulates repC expression. Results To identify the minimal region of the Rhizobium etli p42d plasmid that is capable of autonomous replication, we amplified different regions of the repABC operon using PCR and cloned the regions into a suicide vector. The resulting vectors were then introduced into R. etli strains that did or did not contain p42d. The minimal replicon consisted of a repC open reading frame under the control of a constitutive promoter with a Shine-Dalgarno sequence that we designed. A sequence analysis of repC revealed the presence of a large A+T-rich region but no iterons or DnaA boxes. Silent mutations that modified the A+T content of this region eliminated the replication capability of the plasmid. The minimal replicon could not be introduced into R. etli strain containing p42d, but similar constructs that carried repC from Sinorhizobium meliloti pSymA or the linear chromosome of Agrobacterium tumefaciens replicated in the presence or absence of p42d, indicating that RepC is an incompatibility factor. A hybrid gene construct expressing a RepC protein with the first 362 amino acid residues from p42d RepC and the last 39 amino acid residues of RepC from SymA was able to replicate in the presence of p42d. Conclusions RepC is the only element encoded in the repABC operon of the R. etli p42d plasmid that is necessary and sufficient for plasmid replication and is probably the initiator protein. The ori

  7. RepA-WH1 prionoid

    Science.gov (United States)

    de la Espina, Susana Moreno-Díaz; Fernández-Tresguerres, M Elena; Gasset-Rosa, Fátima

    2011-01-01

    The intricate complexity at the molecular and cellular levels of the processes leading to the development of amyloid proteinopathies is somehow counterbalanced by their common, universal structural basis. The later has fueled the quest for suitable model systems to study protein amyloidosis under quasi-physiological conditions in vitro and in simpler organisms in vivo. Yeast prions have provided several of such model systems, yielding invaluable insights on amyloid structure, dynamics and transmission. However, yeast prions, unlike mammalian PrP, do not elicit any proteinopathy. We have recently reported that engineering RepA-WH1, a bacterial DNA-toggled protein conformational switch (dWH1→mWH1) sharing some analogies with nucleic acid-promoted PrPC→PrPSc replication, enables control on protein amyloidogenesis in vitro. Furthermore, RepA-WH1 gives way to a non-infectious, vertically-transmissible (from mother to daughter cells) amyloid proteinopathy in Escherichia coli. RepA-WH1 amyloid aggregates efficiently promote aging in bacteria, which exhibit a drastic lengthening in generation time, a limited number of division cycles and reduced fitness. The RepA-WH1 prionoid opens a direct means to untangle the general pathway(s) for protein amyloidosis in a host with reduced genome and proteome. PMID:21293179

  8. Mercury in Nelson's Sparrow Subspecies at Breeding Sites

    Science.gov (United States)

    Winder, Virginia L.; Emslie, Steven D.

    2012-01-01

    Background Mercury is a persistent, biomagnifying contaminant that can cause negative effects on ecosystems. Marshes are often areas of relatively high mercury methylation and bioaccumulation. Nelson's Sparrows (Ammodramus nelsoni) use marsh habitats year-round and have been documented to exhibit tissue mercury concentrations that exceed negative effects thresholds. We sought to further characterize the potential risk of Nelson's Sparrows to mercury exposure by sampling individuals from sites within the range of each of its subspecies. Methodology/Principal Findings From 2009 to 2011, we captured adult Nelson's Sparrows at sites within the breeding range of each subspecies (A. n. nelsoni: Grand Forks and Upham, North Dakota; A. n. alterus: Moosonee, Ontario; and A. n. subvirgatus: Grand Manan Island, New Brunswick) and sampled breast feathers, the first primary feather (P1), and blood for total mercury analysis. Mean blood mercury in nelsoni individuals captured near Grand Forks ranged from 0.84±0.37 to 1.65±1.02 SD ppm among years, between 2.0 and 4.9 times as high as concentrations at the other sites (Pmercury did not vary among sites within a given sampling year (site means ranged from 0.98±0.69 to 2.71±2.93 ppm). Mean P1 mercury in alterus (2.96±1.84 ppm fw) was significantly lower than in any other sampled population (5.25±2.24–6.77±3.51 ppm; P≤0.03). Conclusions/Significance Our study further characterized mercury in Nelson's Sparrows near Grand Forks; we documented localized and potentially harmful mercury concentrations, indicating that this area may represent a biological mercury hotspot. This finding warrants further research to determine if wildlife populations of conservation or recreational interest in this area may be experiencing negative effects due to mercury exposure. We present preliminary conclusions about the risk of each sampled population to mercury exposure. PMID:22384194

  9. The Nelson Model with Less Than Two Photons

    CERN Document Server

    Galtbayar, A; Yajima, K

    2002-01-01

    We study the spectral and scattering theory of the Nelson model for an atom interacting with a photon field in the subspace with less than two photons. For the free electron-photon system, the spectral property of the reduced Hamiltonian in the center of mass coordinates and the large time dynamics are determined. If the electron is under the influence of the nucleus via spatially decaying potentials, we locate the essential spectrum, prove the absence of singular continuous spectrum and the existence of the ground state, and construct wave operators giving the asymptotic dynamics.

  10. Failure Analysis of Main Flame Deflector Nelson Studs

    Science.gov (United States)

    Long, Victoria

    2009-01-01

    NASA Structures engineers submitted two Nelson refractory studs from the main flame deflector at Launch Complex (LC) 39 A for analysis when they were observed to be missing a significant amount of material after launch. The damaged stud and an unused comparative stud were analyzed by macroscopic and microscopic examination along with metallographic evaluation of the microstructure. The stud lost material due to a combination of erosion and corrosion. Plain carbon steel readily forms an oxide layer in the coastal launch environment at Kennedy Space Center. The blast during a launch removes this brittle oxide layer, which then forms again post-launch, thereby further removing material. No indications of melting were observed.

  11. Mercury in Nelson's Sparrow subspecies at breeding sites.

    Directory of Open Access Journals (Sweden)

    Virginia L Winder

    Full Text Available BACKGROUND: Mercury is a persistent, biomagnifying contaminant that can cause negative effects on ecosystems. Marshes are often areas of relatively high mercury methylation and bioaccumulation. Nelson's Sparrows (Ammodramus nelsoni use marsh habitats year-round and have been documented to exhibit tissue mercury concentrations that exceed negative effects thresholds. We sought to further characterize the potential risk of Nelson's Sparrows to mercury exposure by sampling individuals from sites within the range of each of its subspecies. METHODOLOGY/PRINCIPAL FINDINGS: From 2009 to 2011, we captured adult Nelson's Sparrows at sites within the breeding range of each subspecies (A. n. nelsoni: Grand Forks and Upham, North Dakota; A. n. alterus: Moosonee, Ontario; and A. n. subvirgatus: Grand Manan Island, New Brunswick and sampled breast feathers, the first primary feather (P1, and blood for total mercury analysis. Mean blood mercury in nelsoni individuals captured near Grand Forks ranged from 0.84 ± 0.37 to 1.65 ± 1.02 SD ppm among years, between 2.0 and 4.9 times as high as concentrations at the other sites (P<0.01. Breast feather mercury did not vary among sites within a given sampling year (site means ranged from 0.98 ± 0.69 to 2.71 ± 2.93 ppm. Mean P1 mercury in alterus (2.96 ± 1.84 ppm fw was significantly lower than in any other sampled population (5.25 ± 2.24-6.77 ± 3.51 ppm; P ≤ 0.03. CONCLUSIONS/SIGNIFICANCE: Our study further characterized mercury in Nelson's Sparrows near Grand Forks; we documented localized and potentially harmful mercury concentrations, indicating that this area may represent a biological mercury hotspot. This finding warrants further research to determine if wildlife populations of conservation or recreational interest in this area may be experiencing negative effects due to mercury exposure. We present preliminary conclusions about the risk of each sampled population to mercury exposure.

  12. Nelson 综合征的显微外科治疗%Microsurgical treatment of Nelson's syndrome

    Institute of Scientific and Technical Information of China (English)

    幸兵; 任祖渊; 苏长保; 王任直; 杨义; 胡尧飞

    2002-01-01

    Objective To discuss the etiology, diagnostic criteria and treatment of Nelson's syndrome.Methods Twenty-three patients with Nelson's syndrome who were treated in our department over the last 19 years were analyzed retrospectively. Removal of adenoma by the transsphenoidal approach was done in 21 patients and by transfrontal craniotomy in 2. The follow-up period ranged from six months to nine years.Results The incidence of Nelson's syndrome was 7.7% in a series of 300 patients with Cushing's disease treated by microsurgery in the same period. Hyperpigmentation was relieved and adrenocorticotropic hormone (ACTH) levels decreased in all patients after tumor excision. Eight patients with visual disturbance improved after surgery. The curative and remission rates were 56.5% and 26.1%, respectively. Conclusions Transsphenoidal microsurgical removal of pituitary ACTH adenoma is the first choice in the prevention and treatment of Nelson's syndrome. Regular follow-up examinations should be performed over a long time.%目的分析和探讨Nelson综合征的病因、诊断标准和治疗方法.方法 对我科手术治疗的23例病例进行回顾性研究.21例经蝶窦手术,2例经额开颅,随访时间半年~9年.结果 本组23例Nelson综合征,占同期手术治疗的库欣病的7.7%.垂体腺瘤切除后皮肤色素沉着减轻,血ACTH水平下降,8例视力视野障碍术后均改善,治愈率56.5%,缓解率26.1%.结论 经蝶窦垂体ACTH腺瘤切除是预防和治疗Nelson综合征的首选方法,术后应定期随访.

  13. A SOCIEDADE CARIOCA NOS CONTOS DE NELSON RODRIGUES

    Directory of Open Access Journals (Sweden)

    Valdemar Valente Junior (UniverCidade

    2013-10-01

    Full Text Available A coletânea de contos intitulada A vida como ela é..., de Nelson Rodrigues, como um retrato da classe média suburbana do Rio de Janeiro nos anos cinquenta. As situações que envolvem sexo e violência no contexto de transformações econômicas e sociais da sociedade brasileira. A decadência da moral burguesa embutida nessas narrativas como uma continuidade dos temas explorados em suas peças.PALAVRAS-CHAVE: Narrativa. Sociedade. Violência. Casamento. Adultério. Abstract The collection of short-stories named A vida como ela é…, by Nelson Rodrigues, as a picture of the suburban middle class of Rio de Janeiro in the fifties. The situations that involve sex and violence in the context of economic and social transformations of the brazilian society. The decadence of the bourgeois moral inserted in that narratives like a continuity of the themes explored in his plays.KEYWORDS: Narrative. Society. Violence. Wedding. Adultery

  14. Rebuttal to Nelson et al. 'Response to Bodin and Grote regarding postdoctoral recruitment in clinical neuropsychology'.

    Science.gov (United States)

    Bodin, Doug; Grote, Christopher L

    2016-07-01

    Nelson et al. provided a response to our commentary on the postdoctoral match in clinical neuropsychology. In this brief rebuttal, we will focus on statements from Nelson et al. that we believe are factual inaccuracies or misunderstandings of some of the points we made in our commentary. In addition, we will comment briefly on the proposed guidelines offered in their response.

  15. 78 FR 56224 - Hydro Nelson, Ltd.; Hydro-WM, LLC; Notice of Transfer of Exemption

    Science.gov (United States)

    2013-09-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Hydro Nelson, Ltd.; Hydro-WM, LLC; Notice of Transfer of Exemption 1. By... in Nelson County, Virginia. The transfer of an exemption does not require Commission approval. \\1\\...

  16. Education Bill passes

    Science.gov (United States)

    Richman, Barbara T.

    On March 2 the U.S. House of Representatives passed a bill authorizing $425 million for science and mathematics education in fiscal 1984; the authorization is $350 million more than President Ronald Reagan requested in his budget proposal (Eos, February 15, 1983, p. 65).H.R. 1310 allocates $295 million to the Department of Education not only to improve precollege instruction in science and math, but to beef up foreign language training to aid in improving international communication among scientists. The bill also allots $130 million to the National Science Foundation for a variety of programs, the lion's share of which aims to upgrade research equipment at colleges and universities. It is hoped that industry will match the $100 million targeted for this program.

  17. Open-Source Wax RepRap 3-D Printer for Rapid Prototyping Paper-Based Microfluidics.

    Science.gov (United States)

    Pearce, J M; Anzalone, N C; Heldt, C L

    2016-08-01

    The open-source release of self-replicating rapid prototypers (RepRaps) has created a rich opportunity for low-cost distributed digital fabrication of complex 3-D objects such as scientific equipment. For example, 3-D printable reactionware devices offer the opportunity to combine open hardware microfluidic handling with lab-on-a-chip reactionware to radically reduce costs and increase the number and complexity of microfluidic applications. To further drive down the cost while improving the performance of lab-on-a-chip paper-based microfluidic prototyping, this study reports on the development of a RepRap upgrade capable of converting a Prusa Mendel RepRap into a wax 3-D printer for paper-based microfluidic applications. An open-source hardware approach is used to demonstrate a 3-D printable upgrade for the 3-D printer, which combines a heated syringe pump with the RepRap/Arduino 3-D control. The bill of materials, designs, basic assembly, and use instructions are provided, along with a completely free and open-source software tool chain. The open-source hardware device described here accelerates the potential of the nascent field of electrochemical detection combined with paper-based microfluidics by dropping the marginal cost of prototyping to nearly zero while accelerating the turnover between paper-based microfluidic designs. © 2016 Society for Laboratory Automation and Screening.

  18. de la República de Cuba

    Directory of Open Access Journals (Sweden)

    Daniel Ponce de León Lima

    2008-01-01

    Full Text Available Se presenta un esbozo de las estrategias a seguir para la inserción de la información edafológica en la Infraestructura de Datos Espaciales de la República de Cuba, a partir de un análisis del estado actual de desarrollo de la cartografía digital edafológica de Cuba y del desarrollo de bases de datos de la información de perfiles de suelo asociada. Se proponen una serie de tareas para lograr estos fines

  19. Mailis Reips : Prezhde vsego neobhodimo natshat / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2006-01-01

    Haridusminister Mailis Reps kakskeelse hariduse vajalikkusest vene õppekeelega koolides, noorte keeleoskusest, eesti keele õpetamise kvaliteedist, õpetajate eesti keele oskusest, õppetöö kvaliteedist

  20. Nelson Mandela's defence: A psychological capital documentary analysis

    Directory of Open Access Journals (Sweden)

    Rene van Wyk

    2014-11-01

    Full Text Available This qualitative documentary analysis examines Nelson Mandela�s defence statement at the Rivonia Trial, Pretoria Supreme Court, on 20 April 1964. The defence document is analysed through the psychological capital lens, depicting themes that support the constructs of hope, efficacy, resilience and optimism. Psychological capital characteristics played a major role in the initial non-violent policies of negotiation. The inevitable establishment of Umkhonto we Sizwe followed, as a result of the increased restrictions and unwillingness of government to negotiate and collaborate. Mandela showed a determined spirit to unite the country. The discussion gives insight into Mandela�s authentic psychological capital leadership under difficult political and personal circumstances. Some implications are indicated in adopting Mandela�s psychological characteristics for personal reform.

  1. A dimeric Rep protein initiates replication of a linear archaeal virus genome: implications for the Rep mechanism and viral replication

    DEFF Research Database (Denmark)

    Oke, Muse; Kerou, Melina; Liu, Huanting

    2011-01-01

    that a protein encoded in the 34-kbp genome of the rudivirus SIRV1 is a member of the replication initiator (Rep) superfamily of proteins, which initiate rolling-circle replication (RCR) of diverse viruses and plasmids. We show that SIRV Rep nicks the viral hairpin terminus, forming a covalent adduct between...... positioned active sites, each with a single tyrosine residue, work in tandem to catalyze DNA nicking and joining. We propose a novel mechanism for rudivirus DNA replication, incorporating the first known example of a Rep protein that is not linked to RCR. The implications for Rep protein function and viral...

  2. Civismo, República e manuais escolares

    Directory of Open Access Journals (Sweden)

    Cleber Santos Vieira

    2012-01-01

    Full Text Available O artigo analisa aspectos do civismo no alvorecer da República brasileira, com ênfase na pesquisa sobre dois livros escolares: História do Brasil ensinada pela biografia de seus heróis, de Silvio Romero (1890; e A História de São Paulo pela biografia de seus nomes mais notáveis (1895, publicado por Tancredo Amaral. Por um lado, trata-se de apresentar nuances da Historia Magistra Vitae presentes nestes objetos da cultura material. Por outro, de destacar em que medida suas histórias foram pontuadas por divergências em torno da questão educação ou instrução cívica pela afirmação de um civismo de coloração regional, bem como palco de conflitos entre protagonistas do republicanismo paulista.

  3. Survey of waterfowl populations and habitat on Nelson Island, Alaska: Progress report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report is a progress report on the survey of waterfowl populations and habitat on Nelson Island in Alaska. Aerial surveys and ground surveys are covered....

  4. Fathers of the Nation: Barack Obama Addresses Nelson Mandela

    Directory of Open Access Journals (Sweden)

    Elisa Bordin

    2014-11-01

    Full Text Available This essay analyzes Barack Obama’s Nelson Mandela Memorial speech together with other seminal texts of Obama’s political and personal creed, such as his book Dreams from My Father (1995 and his speech “A More Perfect Union” (2008. This reading becomes helpful to understand Mandela’s transnational power, which Obama uses to comment on the United States by comparing Madiba to other American “fathers of the nation.” Thus, he uproots Mandela’s from a specifically South African legacy, expands his figure, and addresses him as a transnational father of his own nation, whose power, influence, and example transcend South African borders. As a consequence of this enlargement and transnational validation of Mandela’s figure, the speech delivered at the Memorial becomes an occasion to tackle American past and future, while the memory of Madiba and his driving example in Obama’s life serve to reinforce previous positions conveyed in other discourses by the American President, such as the “A More Perfect Union” speech delivered in Philadelphia in 2008.

  5. Josh Billings (Henry Wheeler Shaw).

    Science.gov (United States)

    Kesterson, David B.

    Designed for use by the general reader, the college student, and the teacher, this book analyzes the life and literary career of Josh Billings (Henry Wheeler Shaw), emphasizing his literary ventures and artistic talents. The analysis reveals Billings' talents as a subtle humorist, homespun philosopher, and artist of the essay. Chapters include…

  6. Pensar la república : revolución y positivismo en los orígenes de la tercera república francesa

    OpenAIRE

    López Alcañiz, Vladimir

    2005-01-01

    El artículo reflexiona entorno la idea de república durante la tercera república francesa. El artículo incluye una bibliografía comentada referente al legado de la Revolución y los orígenes de la República. L’article reflexiona entorn la idea de república durant la tercera república francesa. L’article inclou una bibliografia comentada referent al llegat de la Revolució i els orígens de la República. The article focus on republic thought during the third french republic. It includes a b...

  7. PepGMV Rep-Protein Expression in Mammalian Cells

    Science.gov (United States)

    Chapa-Oliver, Angela María; Mejía-Teniente, Laura; García-Gasca, Teresa; Guevara-Gonzalez, Ramon Gerardo; Torres-Pacheco, Irineo

    2012-01-01

    The Geminiviruses genome is a small, single strand DNA that replicates in the plant cell nucleus. Analogous to animal DNA viruses, Geminiviruses depend on the host replication machinery to amplify their genomes and only supply the factors required to initiate their replication. Consequently, Geminiviruses remove the cell-cycle arrest and induce the host replication machinery using an endocycle process. They encode proteins, such as the conserved replication-associated proteins (Rep) that interact with retinoblastoma-like proteins in plants and alter the cell division cycle in yeasts. Therefore, the aim of this work is to analyze the impact of Pepper Golden Mosaic Virus (PepGMV) Rep protein in mammalian cells. Results indicate that the pTracer-SV40:Rep construction obtained in this work can be used to analyze the Rep protein effect in mammalian cells in order to compare the cell cycle regulation mechanisms in plants and animals. PMID:23170183

  8. República Saharaui: una nación cerca del olvido

    OpenAIRE

    Valdez Ugalde, María Cristina

    2010-01-01

    1. Párrafo de Inicio 2. Desarrollo a. República Saharaui o Sahara Occidental b. El gobierno de la República Saharaui c. La gente en la República Saharaui d. La ONU y la República Saharaui 3. Párrafo de Cierre 4. Referencias 5. Notas de enseñanza

  9. Patient bill of rights 2001.

    Science.gov (United States)

    Benjamin, G C

    2001-01-01

    Breaking gridlock on managed care reform, a bipartisan coalition in Congress introduced the newest version of a patient bill of rights. Unlike last year's ill-fated Norwood-Dingell bill, the Bipartisan Patient Protection Act of 2001 has strong bipartisan support; concern remains, however, on the provisions that allow patients to sue their managed care plan. The debate now focuses on the type of liability reform that Congress and the White House can agree on. If they are able to agree, a patient bill of rights may soon become law.

  10. Patients Bill of Rights Data

    Data.gov (United States)

    U.S. Department of Health & Human Services — Reducing Costs, Protecting Consumers - The Affordable Care Act on the One Year Anniversary of the Patients Bill of Rights For too long, too many hard working...

  11. Specific functions of the Rep and Rep' proteins of porcine circovirus during copy-release and rolling-circle DNA replication

    Science.gov (United States)

    The roles of two porcine circovirus replication initiator proteins, Rep and Rep', in generating copy-release and rolling-circle DNA replication intermediates were determined. Rep uses the supercoiled closed-circular genome (ccc) to initiate leading-strand synthesis (identical to copy-release replica...

  12. PREDIKSI PUNCAK KEMATANGAN BUAH NAGA MELALUI PENGUKURAN GULA REDUKSI DENGAN METODE NELSON-SOMOGYI

    Directory of Open Access Journals (Sweden)

    Alimuddin -

    2016-01-01

    Full Text Available Prediction of dragon fruit maturation peak by measuring reductor sugar with nelson-somogyi method have been done. Prediction was done by using three modes which are experimental result, regression model and first derivation. Age of the fruit which used in this research were 1, 3, 5 and 7 weeks old. Based on the result of this research can be concluded that maturation peak of dragon fruit happens at between 5 until 6 weeks old. Keywords: Dragon Fruit, Reductor Sugar and Nelson-Somogyi Method.

  13. 78 FR 66353 - EAM Nelson Holdings, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Science.gov (United States)

    2013-11-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission EAM Nelson Holdings, LLC; Supplemental Notice That Initial Market-Based Rate...-referenced proceeding, of EAM Nelson Holdings, LLC's application for market-based rate authority, with...

  14. A República Mundial de Otfried Höffe

    Directory of Open Access Journals (Sweden)

    Diego Carlos Zanella

    2015-03-01

    Full Text Available Esse texto tem por objetivo apresentar em linhas gerais a proposta de Otfried Höffe sobre a república mundial. Para tanto, iniciar-se-á com o ponto de partida de Höffe, a saber, o fenômeno da globalização, de onde são apontadas as principais atividades e problemas da república mundial. Em seguida, passa-se a analisar os dois níveis da proposta, o nível nacional e o nível internacional ou global da república mundial. Por fim, concluir-se-á com uma tentativa de comparação da proposta de Höffe com a ideia de uma federação de Estados livres apresentada por Immanuel Kant em À paz perpétua.

  15. Senate passes clean air bill

    Science.gov (United States)

    In an 89 to 11 vote the Senate passed a clean air bill aimed at reducing pollution by the turn of the century by imposing tougher controls on American industry. The bill is the first revision of the Clean Air Act of 1970 in 13 years and calls for new limits on auto pollution to clean up smog in most U.S. cities, decreasing by half emissions by power plants that cause acid rain to protect the ecology, and increasing technological controls on factories to protect against cancer-causing and toxic substances. The bill will add about $20 billion per year to the estimated $33 billion cost of complying with current pollution laws.

  16. Central Bank (Supervision and Enforcement) (Amendment) Bill 2016: Legislative Bill

    DEFF Research Database (Denmark)

    Butler, Graham; Rock, Noel

    2016-01-01

    Private Members' Bill (legislation) introduced in Dáil Éireann (House of Deputies), Houses of the Oireachtas (Irish Parliament). An Act to amend sections 49 and 51 of the Central Bank (Supervision and Enforcement) Act 2013 to ensure the powers exercised by the Central Bank of Ireland to make...

  17. 3D printing with RepRap cookbook

    CERN Document Server

    Salinas, Richard

    2014-01-01

    A systematic guide consisting of over 100 recipes which focus on helping you understand the process of 3D printing using RepRap machines. The book aims at providing professionals with a series of working recipes to help make their fuzzy notions into real, saleable projects/objects using 3D printing technology. This book is for novice designers and artists who own a RepRap-based 3D printer, have fundamental knowledge of its working, and who desire to gain better mastery of the printing process. For the more experienced user, it will provide a handy visual resource, with side-by-side comparisons

  18. Images en mouvement stockage, repérage, indexation

    CERN Document Server

    Turner, James

    1998-01-01

    L'avènement puis la fusion des nouveaux modes de communication que sont l'informatique, les télécommunications et l'audiovisuel ont mis à la portée de tous une grande quantité d'images fixes et en mouvement dont la conservation et le repérage risquent de prendre des proportions démesurées. Le présent ouvrage veut offrir aux responsables de collection des repères pour aborder la problématique de l'indexation des images et faciliter l'accès des usagers à ces images.

  19. Towards an itinerary of ideas : intertextual mapping in the rhetoric of Nelson Mandela

    NARCIS (Netherlands)

    Cawood, C.

    2016-01-01

    This paper explores explicit and implicit forms of intertextuality in the rhetoric of Nelson Mandela. Intertextuality is viewed as a mechanism of thought and part of the process of dianoia in Classical rhetoric as conceptualised by Aristotle and is also considered crucial in the ethos of a rhetor. T

  20. Shaping Influences on the Leadership of Genghis Khan, George Washington, and Nelson Mandela: Applications for Educators

    Science.gov (United States)

    Bongila, Jean-Pierre

    2011-01-01

    Using a prosopographical methodology this study examines common leadership influences that might have existed among Genghis Khan, George Washington, and Nelson Mandela. Shoup (2005) suggests that the following seven influences have contributed to nurturing the leadership of 12 renowned individuals: involved parents, happy childhood, formal,…

  1. Social Justice and Human Rights in Education Policy Discourse: Assessing Nelson Mandela's Legacy

    Science.gov (United States)

    Gebremedhin, Abrehet; Joshi, Devin

    2016-01-01

    Twenty years after South Africa's democratisation, Nelson Mandela's passing has prompted scholars to examine his legacy in various domains. Here we take a look at his legacy in education discourse. Tracing Mandela's thoughts and pronouncements on education we find two major emphases: a view of education as a practical means to economic…

  2. Kunda "liumägi" / Ago Kastemäe, Huviklubi Nelson

    Index Scriptorium Estoniae

    Kastemäe, Ago

    2014-01-01

    Millistel tingimustel on võimalik Kunda jõel paiknevast hüdroelektrijaama tammist süsta või raftiga alla sõita. Huviklubi Nelson pakub koostöös Lontova Seikluspargiga Kunda jõel juhendajatega raftimatku

  3. Kunda "liumägi" / Ago Kastemäe, Huviklubi Nelson

    Index Scriptorium Estoniae

    Kastemäe, Ago

    2014-01-01

    Millistel tingimustel on võimalik Kunda jõel paiknevast hüdroelektrijaama tammist süsta või raftiga alla sõita. Huviklubi Nelson pakub koostöös Lontova Seikluspargiga Kunda jõel juhendajatega raftimatku

  4. Quantification of growth patterns of screen-detected lung cancers : The NELSON study

    NARCIS (Netherlands)

    Heuvelmans, Marjolein A.; Vliegenthart, Rozemarijn; de Koning, Harry J.; Groen, Harry J M; van Putten, Michel J A M; Yousaf-Khan, Uraujh; Weenink, Carla; Nackaerts, Kristiaan; de Jong, Pim A.; Oudkerk, Matthijs

    Objectives Although exponential growth is assumed for lung cancer, this has never been quantified in vivo. Aim of this study was to evaluate and quantify growth patterns of lung cancers detected in the Dutch-Belgian low-dose computed tomography (CT) lung cancer screening trial (NELSON), in order to

  5. Quantification of growth patterns of screen-detected lung cancers : The NELSON study

    NARCIS (Netherlands)

    Heuvelmans, Marjolein A.; Vliegenthart, Rozemarijn; de Koning, Harry J.; Groen, Harry J M; van Putten, Michel J A M; Yousaf-Khan, Uraujh; Weenink, Carla; Nackaerts, Kristiaan; de Jong, Pim A.|info:eu-repo/dai/nl/287955672; Oudkerk, Matthijs

    2017-01-01

    Objectives Although exponential growth is assumed for lung cancer, this has never been quantified in vivo. Aim of this study was to evaluate and quantify growth patterns of lung cancers detected in the Dutch-Belgian low-dose computed tomography (CT) lung cancer screening trial (NELSON), in order to

  6. "Passageless" Administration of the Nelson-Denny Reading Comprehension Test: Associations with IQ and Reading Skills

    Science.gov (United States)

    Ready, Rebecca E.; Chaudhry, Maheen F.; Schatz, Kelly C.; Strazzullo, Sarah

    2013-01-01

    There are few tests that assess reading comprehension in adults, but these tests are needed for a comprehensive assessment of reading disorders (RD). "The Nelson-Denny Reading Test" (NDRT) has a long-passage reading comprehension component that can be used with adolescents and adults. A problem with the NDRT is that reading comprehension…

  7. Radical Questioning on the Long Walk to Freedom: Nelson Mandela and the Practice of Critical Reflection

    Science.gov (United States)

    Brookfield, Stephen

    2008-01-01

    Nelson Mandela's autobiography "The Long Walk to Freedom" describes how an iconic political activist and freedom fighter reflected on, and sometimes modified, four core assumptions at the heart of his struggle to overturn the White supremacist, minority hegemony and create a free South Africa. Critical reflection's focus is on…

  8. Celebrating the Hero in All of Us: An Interview with Kadir Nelson

    Science.gov (United States)

    Sableski, Mary-Kate; Arnold, Jackie Marshall; Adomat, Donna Sayers

    2015-01-01

    Books provide an opportunity through which children can learn what it means to be in the world and to respond flexibly and creatively to a diverse range of situations. Author/illustrator Kadir Nelson creates books that provide these opportunities for readers of all ages. A dominant theme in current conversations surrounding children's literature…

  9. Lung cancer screening in the NELSON trial: balancing harms and benefits

    NARCIS (Netherlands)

    N. Horeweg (Nanda)

    2014-01-01

    markdownabstract__Abstract__ In this thesis, the harms and benefits of lung cancer screening using low-dose computed tomography were investigated. Data of the Dutch-Belgian NELSON trial were used to quantify its harms and benefits and develop strategies to improve the balance between them. If the N

  10. "Passageless" Administration of the Nelson-Denny Reading Comprehension Test: Associations with IQ and Reading Skills

    Science.gov (United States)

    Ready, Rebecca E.; Chaudhry, Maheen F.; Schatz, Kelly C.; Strazzullo, Sarah

    2013-01-01

    There are few tests that assess reading comprehension in adults, but these tests are needed for a comprehensive assessment of reading disorders (RD). "The Nelson-Denny Reading Test" (NDRT) has a long-passage reading comprehension component that can be used with adolescents and adults. A problem with the NDRT is that reading comprehension…

  11. Shaping Influences on the Leadership of Genghis Khan, George Washington, and Nelson Mandela: Applications for Educators

    Science.gov (United States)

    Bongila, Jean-Pierre

    2011-01-01

    Using a prosopographical methodology this study examines common leadership influences that might have existed among Genghis Khan, George Washington, and Nelson Mandela. Shoup (2005) suggests that the following seven influences have contributed to nurturing the leadership of 12 renowned individuals: involved parents, happy childhood, formal,…

  12. Coherent Backscattering: Conceptions and Misconceptions (Reply to Comments by Bruce W. Hapke and Robert M. Nelson)

    Science.gov (United States)

    Tishkovets, Victor P.; Mishchenko, Michael

    2010-01-01

    Although the note by Hapke and Nelson has virtually no relevance to our original publication, it contains a number of statements that are misleading and/or wrong. We, therefore, use this opportunity to dispel several profound misconceptions that continue to hinder the progress in remote sensing of planetary surfaces.

  13. STS-26 MS Nelson adjusts ADSF power cable on Discovery's middeck

    Science.gov (United States)

    1988-01-01

    STS-26 Mission Specialist (MS) George D. Nelson adjusts power cable on automated directional solidification furnace (ADSF) support electronics package. ADSF is located in forward (starboard side) lockers on Discovery's, Orbiter Vehicle (OV) 103's, middeck. ADSF consists of the furnace container (left) and the control electronics container (right). An Air National Guard, Houston, Texas, decal appears on middeck locker above ADSF.

  14. 77 FR 42327 - Proposed Supplementary Rules for the Morley Nelson Snake River Birds of Prey National...

    Science.gov (United States)

    2012-07-18

    ...The Bureau of Land Management (BLM) is proposing supplementary rules for all BLM-administered public lands within the approximately 483,700-acre Morley Nelson Snake River Birds of Prey National Conservation Area (NCA), addressed in the September 2008 Resource Management Plan (RMP) and Record of Decision (ROD). The Snake River Birds of Prey NCA RMP identifies implementation level decisions......

  15. Corner Office: Polaris's Bill Schickling

    Science.gov (United States)

    Fialkoff, Francine; Hadro, Josh

    2010-01-01

    Bill Schickling has spent a good chunk of his professional life at what is now Polaris Library Systems, shaping both the older Galaxy system and the newer Polaris integrated library system (ILS). When he joined the company as a programmer in 1987, it was still part of Gaylord, known mostly for its furniture and supplies division. Schickling was…

  16. Bill Gates eyes healthcare market.

    Science.gov (United States)

    Dunbar, C

    1995-02-01

    The entrepreneurial spirit is still top in Bill Gates' mind as he look toward healthcare and other growth industries. Microsoft's CEO has not intention of going the way of other large technology companies that became obsolete before they could compete today.

  17. Educational Quality Bill of Rights

    Science.gov (United States)

    Center for Law and Education (NJ3), 2009

    2009-01-01

    This paper presents two forms of the Educational Quality Bill of Rights (EQBR). The first is a "one-page version", with a very brief single sentence identification of a key element of quality education in response to each of the key questions about the school (covering standards/learning goals, curriculum, instruction, etc.). The second is a "much…

  18. Las Garrapatas de la República de Colombia

    Directory of Open Access Journals (Sweden)

    Osorno Mesa Ernesto

    1942-04-01

    Full Text Available El presente estudio comprende las especies de garrapatas colombianas conocidas, como también las de la República de Panamá. En las claves incluyo las especies descritas y halladas en Colombia. Las referencias fueron tomadas de las descripciones originales y de todas las publicaciones sobre garrapatas de los dos países.

  19. El movimiento no parlamentario en la Segunda República

    Directory of Open Access Journals (Sweden)

    Víctor ALBA

    2010-02-01

    Full Text Available Cuando se escribe sobre la Segunda República española se hace frecuente referencia a las derechas, los partidos republicanos y los socialistas. Menos frecuentes son las alusiones al movimiento narcosindicalista y casi nulas las que se relacionan con los partidos marxistas menores.

  20. Rehabilitation Education Program for Stroke (REPS): Learning and Practice Outcomes

    Science.gov (United States)

    McEwen, Sara; Szurek, Kristina; Polatajko, Helene J.; Rappolt, Susan

    2005-01-01

    Introduction: New research knowledge acquired from Web-based sources may have a better chance of being translated into practice when accompanied by additional educational strategies. This study was undertaken to investigate that hypothesis. Methods: The Rehabilitation Education Program for Stroke (REPS) combines a self-directed online learning…

  1. Las garrapatas de la república de colombia

    OpenAIRE

    Osorno Mesa Ernesto

    2012-01-01

    El presente estudio comprende las especies de garrapatas colombianas conocidas, como también las de la República de Panamá. En las claves incluyo las especies descritas y halladas en Colombia. Las referencias fueron tomadas de las descripciones originales y de todas las publicaciones sobre garrapatas de los dos países.

  2. Overview of RepLab 2013: Evaluating online reputation monitoring systems

    NARCIS (Netherlands)

    Amigó, E.; Carrillo de Albornoz, J.; Chugur, I.; Corujo, A.; Gonzalo, J.; Martín, T.; Meij, E.; de Rijke, M.; Spina, D.

    2013-01-01

    This paper summarizes the goals, organization, and results of the second RepLab competitive evaluation campaign for Online Reputation Management Systems (RepLab 2013). RepLab focused on the process of monitoring the reputation of companies and individuals, and asked participant systems to annotate

  3. Overview of RepLab 2012: Evaluating Online Reputation Management Systems

    NARCIS (Netherlands)

    Amigó, E.; Corujo, A.; Gonzalo, J.; Meij, E.; de Rijke, M.

    2012-01-01

    This paper summarizes the goals, organization and results of the first RepLab competitive evaluation campaign for Online Reputation Management Systems (RepLab 2012). RepLab focused on the reputation of companies, and asked participant systems to annotate different types of information on tweets

  4. Specific functions of the Rep and Rep׳ proteins of porcine circovirus during copy-release and rolling-circle DNA replication.

    Science.gov (United States)

    Cheung, Andrew K

    2015-07-01

    The roles of two porcine circovirus replication initiator proteins, Rep and Rep׳, in generating copy-release and rolling-circle DNA replication intermediates were determined. Rep uses the supercoiled closed-circular genome (ccc) to initiate leading-strand synthesis (identical to copy-release replication) and generates the single-stranded circular (ssc) genome from the displaced DNA strand. In the process, a minus-genome primer (MGP) necessary for complementary-strand synthesis, from ssc to ccc, is synthesized. Rep׳ cleaves the growing nascent-strand to regenerate the parent ccc molecule. In the process, a Rep׳-DNA hybrid containing the right palindromic sequence (at the origin of DNA replication) is generated. Analysis of the virus particle showed that it is composed of four components: ssc, MGP, capsid protein and a novel Rep-related protein (designated Protein-3).

  5. Bill Viola : repertorio de pasiones

    Directory of Open Access Journals (Sweden)

    Yayo Aznar

    2004-01-01

    Full Text Available El texto estudia las obras de Bill Viola unidas en la serie llamada “Las Pasiones” que el artista expuso por primera vez en la National Gallery de Londres en el 2003, analizando la evolución de las pasiones (sobre todo del miedo y de la esperanza desde la fundación del Estado Moderno, y sus consecuencias sobre el control de la sociedad contemporánea.The text studies the Bill Viola’s work of art called “The Passions”, that the artist showed in the National Gallery on London in 2003 for the first time, analyzing the development of the passions (overcoat the fear and the hope and its consequences in the contemporary society.

  6. Bill Gates vil redde Folkeskolen

    DEFF Research Database (Denmark)

    Fejerskov, Adam Moe

    2014-01-01

    Det amerikanske uddannelsessystem bliver for tiden udsat for hård kritik, ledt an af Microsoft stifteren Bill Gates. Gates har indtil videre brugt 3 mia. kroner på at skabe opbakning til tiltag som præstationslønning af lærere og strømlining af pensum på tværs af alle skoler i landet......Det amerikanske uddannelsessystem bliver for tiden udsat for hård kritik, ledt an af Microsoft stifteren Bill Gates. Gates har indtil videre brugt 3 mia. kroner på at skabe opbakning til tiltag som præstationslønning af lærere og strømlining af pensum på tværs af alle skoler i landet...

  7. The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins

    DEFF Research Database (Denmark)

    Madsen, Louise; Kriegenburg, Franziska; Lages Lino Vala, Andrea;

    2011-01-01

    protein named Rep8 or Ubxd6 as a new cofactor of p97. Mouse Rep8 is highly tissue-specific and abundant in gonads. In testes, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Rep8 associates directly with p97 via its UBX domain. We show that Rep8...

  8. Bill Gates vil redde Folkeskolen

    DEFF Research Database (Denmark)

    Fejerskov, Adam Moe

    2014-01-01

    Det amerikanske uddannelsessystem bliver for tiden udsat for hård kritik, ledt an af Microsoft stifteren Bill Gates. Gates har indtil videre brugt 3 mia. kroner på at skabe opbakning til tiltag som præstationslønning af lærere og strømlining af pensum på tværs af alle skoler i landet...

  9. Bill Clinton kaotas tuumakoodikaardi / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2010-01-01

    Oma mälestusteraamatus kirjutab president Bill Clintoni ametiajal staabiülemate ühendkomiteed juhtinud kindral Hugh Shelton, et ühel hetkel olid president Bill Clintonil tuumakohvri kasutamiseks vajalikud koodid mitu kuud kadunud

  10. How the Bill of Rights Was Developed.

    Science.gov (United States)

    Stivison, David V.

    The roots of the Bill of Rights, the first 10 amendments to the United States Constitution, are examined in this document. Attention is directed to English law, specifically the Magna Carta and England's Bill of Rights of 1689, as providing much of the underpinnings for the U.S. Bill of Rights. The text of 15 articles proposed by anti-federalists…

  11. Creating a Bill of Rights Activity Book.

    Science.gov (United States)

    Pellow, Randall A.

    1991-01-01

    Recounts a pilot project in Pennsylvania in which student teachers field-tested Bill of Rights lesson plans and activities for intermediate grade teachers. Describes the project's phases and results, culminating in publication of "Without Them the Bill of Rights Would Be a Bill of Wrongs." Briefly explains the book's 20 lessons. (CH)

  12. How the Bill of Rights Was Developed.

    Science.gov (United States)

    Stivison, David V.

    The roots of the Bill of Rights, the first 10 amendments to the United States Constitution, are examined in this document. Attention is directed to English law, specifically the Magna Carta and England's Bill of Rights of 1689, as providing much of the underpinnings for the U.S. Bill of Rights. The text of 15 articles proposed by anti-federalists…

  13. An evaluation of productivity and mortality factors influencing geese at south Nelson Island, Alaska: A report of results from 1984

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report documents a field investigation of goose productivity in 1984 conducted on Nelson Island on the Yukon Delta National Wildlife Refuge. The procedures used...

  14. Éros est mort à Chicago : Nelson Algren accuse Playboy

    Directory of Open Access Journals (Sweden)

    Frédéric DUMAS

    2011-12-01

    Full Text Available Nelson Algren fut Lauréat du premier National Book Award en 1950 pour The Man with the Golden Arm, dont l’adaptation cinématographique par Otto Preminger eut un immense succès (avec, dans les rôles principaux, Frank Sinatra et Kim Novak. Malgré son talent d’écrivain, il reste avant tout célèbre pour sa relation amoureuse avec Simone de Beauvoir. À la suite de la publication de Lettres à Nelson Algren, il y a quatre ans, la BBC, les télévisions américaine et française ont diffusé plusieurs ém...

  15. Há compatibilidade entre a "tecnologia social" de Nelson e a "causalidade vebleniana" de Hodgson?

    Directory of Open Access Journals (Sweden)

    Octavio A. C. Conceição

    2012-03-01

    Full Text Available Is there compatibility between Nelson's 'Social Technology' and Hodgson's 'Veblenian Causality'? This paper aims to discuss the role and the relationship among the concept of institutions and the economic growth process, through the Neo-Schumpeterian and Institutionalist approaches. Both of them constitute a new research agenda differentiated and opposite to the mainstream. In the first part of the paper we discuss the research agenda proposed by Richard Nelson who emphasizes the necessity to unpack the institution concept throughout the social technology notion. In the second part we discuss Geoffrey Hodgson's contribution that suggests inserting this process in an evolutionary perspective, which has in habits, norms and social behavior his major characteristic.

  16. A república paraense em festa (1890-1911)

    OpenAIRE

    MOURA, Daniella de Almeida

    2008-01-01

    A proposta desta dissertação é discutir a formação do poder simbólico da República Paraense nos seus primeiros anos (1890-1911), observando eventos como a mudança dos nomes de algumas ruas em homenagem ao novo regime, assim como a formulação do calendário republicano, com destaque para os festejos republicanos de 15 e 16 de novembro, datas da Proclamação da República e sua Aclamação no Pará, com o objetivo de analisar seus significados, organização e, principalmente, o entendimento da idéia d...

  17. Identification of Tilletia species using rep-PCR fingerprinting technique

    Directory of Open Access Journals (Sweden)

    Župunski Vesna

    2011-01-01

    Full Text Available Analyzing 167 non-processed seed samples of wheat, it was found that 145 samples (86.8 % were contaminated with Tilletia species, while 22 (13.2 % samples were not contaminated. By using rep-PCR fingerprinting technique, it was found that DNA isolates of T. tritici originated from Serbian wheat samples had 80 % similarity with positive control for T. tritici. One isolate shared similarity of 60% with T. tritici, T. controversa and T. laevis. It was supposed that this isolate belongs to T. bromi. Isolate of T. laevis shared a similarity of 70 % with isolates of T. tritici and T. controversa, while T. walkeri was more than 10 % similar with T. tritici, T. controversa and T. laevis. Although T. controversa and T. tritici had high percent of genetic similarity, they were clustered separately. Our results suggest that rep-PCR fingerprinting could be a useful tool for monitoring presence of morphologically similar Tilletia species in wheat production areas.

  18. Arduino & RepRap - Creating Wealth by Giving it Away

    DEFF Research Database (Denmark)

    2011-01-01

    , growth in wealth is longevity and prosperity. Is it possible to grow wealth independently of money? This talk will be from Adrian Bowyer - creator of RepRap, the open-source replicating 3D printer - and from David Cuartielles - creator of Arduino, the open-source microcontroller. Both projects have...... founded significant and growing industries - and hence significant and growing wealth - by giving away all the data required to build RepRaps and Arduinos completely free. They have also short-circuited most conventional industrial infrastructure by placing the ability to create wealth directly...... in the hands of private individuals. The presenters contend that this is the way of the future: companies, and - more importantly - those private individuals will be giving away their primary products and making a living on the sideline activities that such donations attract. Software has been heading...

  19. STS-26 MS Nelson during training exercise in JSC Mockup and Integration Lab

    Science.gov (United States)

    1988-01-01

    STS-26 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) George D. Nelson, wearing navy blue launch and entry suit (LES) and launch and entry helmet (LEH), is seated in his launch and entry position on crew compartment trainer (CCT) middeck during a training exercise in JSC Mockup and Integration Laboratory Bldg 9A. Visible in the background are the airlock, stowed treadmill, and sleep restraints. NOTE: Photo was taken by William H. Bowers, crew photo instructor, with wide angle lens.

  20. Towards a construction of inclusive collision cross-sections in the massless Nelson model

    OpenAIRE

    2011-01-01

    The conventional approach to the infrared problem in perturbative quantum electrodynamics relies on the concept of inclusive collision cross-sections. A non-perturbative variant of this notion was introduced in algebraic quantum field theory. Relying on these insights, we take first steps towards a non-perturbative construction of inclusive collision cross-sections in the massless Nelson model. We show that our proposal is consistent with the standard scattering theory in the absence of the i...

  1. The search for a more human face for Nelson Mandela: An urgent task

    Directory of Open Access Journals (Sweden)

    Tinyiko Maluleke

    2015-03-01

    Full Text Available For many reasons, reflecting on the life of Nelson Mandela is a precarious exercise. If Mandela is a symbol of the resilience of the human spirit under trying conditions, he is also a symbol that is appropriated in various ways – helpful and unhelpful – by various people. This article explores some of the unhelpful ways in which the name and person of Nelson Mandela is invoked. In particular, the article looks at the hagiographical orientation of several reflections on Mandela, cautioning how some of these may have an effect less noble than originally intended. Accordingly, the article asks: How much can the symbol of Mandela bear? How much more can Mandela give? The logic and rationale of Mandela hagiography is explored. Following his death, there has been an explosion of interest in the life and symbol that is Nelson Mandela. Mandela literature, including multi-media, is on the rise. If the symbol of Mandela is in danger of being ‘cannibalised’, there is also a danger of relegating Mandela to an ahistorical mythical figure. The solution lies in at least two area, namely, the increment of alternative Mandela narratives and the introduction of more critical Mandela narratives. In this regard, Mandela’s own self-understanding as captured in his reflections about his life offer several clues which are explored in this article.

  2. A retrospective study of Nelson's syndrome in Tehran University of Medical Sciences & Health Services, 1985-95

    Directory of Open Access Journals (Sweden)

    Larijani B

    1996-06-01

    Full Text Available Nelson's syndrome is usually characterized by hyperpigmentation, elevated level of ACTH, and pituitary adenoma, which is frequently available as macroadenoma. It is usually occurred in the patients suffering from Cushing's syndrome. Growth of tumor has been revealed in 10-30% of the patients following adrenalectomy. Tumors are often benign in Nelson's syndrome. The selected treatment of Nelson's syndrome are transsphenoidal or transfrontal microsurgery. The role of radiation as prophylactic effect in the patients following adrenalectomy is unknown. In this research Nelson's syndrome have been studied on the patients records who have been hospitalized in Dr.Shariati hospital during the last 10 years. The achieved results show that, among the 49 patients suffering from Cushing syndrome who have referred after operation, 11 patients (22.4% of them have been affected with Nelson's syndrome. The syndromes have been appeared after 3-9 months and with regard to occurrence of Nelson's syndrome in some patients immediately after bilateral adrenalectomy, it is recommended that selecting of the patients for bilateral adrenalectomy should be studied accurately

  3. Sharing China's Bank Restructuring Bill

    Institute of Scientific and Technical Information of China (English)

    Guonan Ma

    2006-01-01

    This paper addresses the questions related to the cost of China's bank restructuring and how it has been financed. We first propose a framework for recognizing losses. Then, we examine the recent major moves by the Chinese Government to repair the country's bank balance sheets. Finally, we explore the implications of the Chinese Government's methods of funding bank restructuring. We find that the Chinese Government has been decisive in confronting the costly task of bank restructuring. So far, Chinese taxpayers have paid most of the bill for bank restructuring.

  4. Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication

    Science.gov (United States)

    Seyffert, Michael; Glauser, Daniel L.; Schraner, Elisabeth M.; de Oliveira, Anna-Paula; Mansilla-Soto, Jorge; Vogt, Bernd; Büning, Hildegard; Linden, R. Michael; Ackermann, Mathias; Fraefel, Cornel

    2017-01-01

    As their names imply, parvoviruses of the genus Dependovirus rely for their efficient replication on the concurrent presence of a helpervirus, such as herpesvirus, adenovirus, or papilloma virus. Adeno-associated virus 2 (AAV2) is such an example, which in turn can efficiently inhibit the replication of each helpervirus by distinct mechanisms. In a previous study we have shown that expression of the AAV2 rep gene is not compatible with efficient replication of herpes simplex virus 1 (HSV-1). In particular, the combined DNA-binding and ATPase/helicase activities of the Rep68/78 proteins have been shown to exert opposite effects on the replication of AAV2 and HSV-1. While essential for AAV2 DNA replication these protein activities account for the Rep-mediated inhibition of HSV-1 replication. Here, we describe a novel Rep mutant (Rep-D371Y), which displayed an unexpected phenotype. Rep-D371Y did not block HSV-1 replication, but still supported efficient AAV2 replication, at least when a double-stranded AAV2 genome template was used. We also found that the capacity of Rep-D371Y to induce apoptosis and a Rep-specific DNA damage response was significantly reduced compared to wild-type Rep. These findings suggest that AAV2 Rep-helicase subdomains exert diverging activities, which contribute to distinct steps of the AAV2 life cycle. More important, the novel AAV2 mutant Rep-D371Y may allow deciphering yet unsolved activities of the AAV2 Rep proteins such as DNA second-strand synthesis, genomic integration or packaging, which all involve the Rep-helicase activity. PMID:28125695

  5. Rep rated long life capacitor development: Phase 1 and 2

    Science.gov (United States)

    Galperin, I.; White, W.; Haskell, K.; Ennis, J.

    1984-09-01

    Polypropylene and polyolefin resins were characterized and processed into capacitor films. New capacitor films were developed--a post oriented processed, two layer polypropylene film and upgraded polyolefin film. Criteria for judging film quality were developed. Field life data were verified with paper/polypropylene capacitors on the Maxwell rep rate facility. A11 polypropylene film capacitors were developed with lifetimes in excess of 10 to the 7th power discharges at energy densities for the finished capacitor of 18.3 J/lb and projected to more than 20 J/lb.

  6. República: gobierno gerencial vs política

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Sánchez Ramos

    2008-01-01

    Full Text Available El presente artículo tiene como propósito revisar el modelo en el que se basó el Partido Acción Nacional (PAN, al gobernar en la presidencia de la República, con Vicente Fox como presidente, demostrando que descuidó la política al preferir los elementos organizacionales por encima de ésta y no reconociéndola como un mecanismo necesario para la disminución de las contradicciones en una sociedad con alta diferenciación social.

  7. A Economia da República Velha,1889-1930

    OpenAIRE

    Gustavo H. B. Franco; Luiz Aranha Correa do Lago

    2011-01-01

    1. Preâmbulo: transição, legado e desafios 2. Do Encilhamento ao Funding Loan 3. O Convênio de Taubaté: a defesa do café e do câmbio 4. O desempenho da economia de 1889 a 1913 em perspectiva 5. A primeira Guerra Mundial, e os “choques adversos” 6. A reconstrução da normalidade nos anos 1920 7. A economia brasileira ao final da República Velha 8. Bibliografia

  8. Stress Monitoring of Mulberry Plants by Finding Rep Using Hyperspectral Data

    Science.gov (United States)

    Bhosle, K.; Musande, V.

    2017-05-01

    Stressed on crop can be monitored using different indices. Red Edge position is good estimator for stress monitoring. The red edge position (REP) is strongly correlated with foliar chlorophyll content. Strong chlorophyll absorption causes the abrupt change in the 680-800 nm region of reflectance spectra of green vegetation. The red edge consist the point of maximum slope between red and near-infrared wavelengths. REP can be used to recognize green zone of the observation area. The REP is present in spectra for vegetation recorded by remote sensing methods. REP is clearer and significant in hyper spectral data as hyper spectral consist of more and continuous bands data. In this paper experiments were carried out for mulberry crop using USGS EO-1 Hyperion data. Atmospheric corrected data is used for classification. Classification is carried out on small cluster of 14 field samples. Ground truth is verified and classified by comparing with Hyperion data. REP is different for different stressed condition of crops and shows healthy and diseased crop condition. Nutritional stresses, diseases, drought of plants are detected using REP. Stressed and healthy field of mulberry are estimated by calculating REP using maximum first derivative, linear interpolation, linear extrapolation method. Finally REP is compared using above methods. It is noticeable difference of REP for healthy and stressed crop. The research indicates that overall accuracy using maximum first derivative was 92.85 % and it was more compared to other methods. Linear extrapolation gives less accuracy compared to linear interpolation method.

  9. Mis saab sinu andekast lapsest? / Tõnis Lukas, Mailis Reps, Peeter Kreitzberg...[jt.] ; intervjueerinud Urve Eslas

    Index Scriptorium Estoniae

    2011-01-01

    Haridusteemalistele küsimustele vastavad haidusminister Tõnis Lukas (IRL), reformierakondlane Paul-Eerik Rummo, sotsiaaldemokraat Peeter Kreitzberg, keskerakondlane Mailis Reps ja Raivo Juurak roheliste nimekirjast

  10. Mycoplasma pneumoniae large DNA repetitive elements RepMP1 show type specific organization among strains.

    Directory of Open Access Journals (Sweden)

    Oxana Musatovova

    Full Text Available Mycoplasma pneumoniae is the smallest self-replicating bacterium with a streamlined genome of 0.81 Mb. Complete genome analysis revealed the presence of multiple copies of four large repetitive elements (designated RepMP1, RepMP2/3, RepMP4 and RepMP5 that are implicated in creating sequence variations among individual strains. Recently, we described RepMP1-associated sequence variations between reference strain M129 and clinical isolate S1 that involved three RepMP1-genes (i.e. mpn130, mpn137 and mpn138. Using PCR and sequencing we analyze 28 additional M. pneumoniae strains and demonstrate the existence of S1-like sequence variants in nine strains and M129-like variants in the remaining nineteen strains. We propose a series of recombination steps that facilitates transition from M129- to S1-like sequence variants. Next we examined the remaining RepMP1-genes and observed no other rearrangements related to the repeat element. The only other detected difference was varying numbers of the 21-nucleotide tandem repeats within mpn127, mpn137, mpn501 and mpn524. Furthermore, typing of strains through analysis of large RepMPs localized within the adhesin P1 operon revealed that sequence divergence involving RepMP1-genes mpn130, mpn137 and mpn138 is strictly type-specific. Once more our analysis confirmed existence of two highly conserved groups of M. pneumoniae strains.

  11. Characterization of mercury and its risk in Nelson's, Saltmarsh, and Seaside Sparrows.

    Directory of Open Access Journals (Sweden)

    Virginia L Winder

    Full Text Available BACKGROUND: Nelson's, Saltmarsh, and Seaside Sparrows (Ammodramus nelsoni, A. caudacutus, and A. maritimus, respectively depend on marsh and wetland habitats--ecosystems in which mercury (Hg bioavailability is notoriously high. The purpose of the present study was to address the potential impact of Hg on these species using first primary and breast feathers as non-destructive biomonitoring tools. METHODS AND PRINCIPAL FINDINGS: Feathers were sampled from wintering sparrows in North Carolina salt marshes (2006-2010. Feather Hg data were used in three risk analysis components (1 Threshold Component--examined feather Hg with regard to published negative effects thresholds; (2 Hg Dynamics Component--examined Hg in sparrows captured multiple times; and (3 Capture Frequency and Survival Component--tested for links between Hg and return frequency and survival. Threshold Component analyses indicated that Hg concentrations in 42-77% of sampled individuals (breast feather n = 879; first primary feather n = 663 were within the range associated with decreased reproduction in other avian species. Hg Dynamics Component analyses demonstrated that Hg increased between first and second captures for Nelson's (n = 9 and Seaside Sparrows (n = 23. Capture Frequency and Survival Component analyses detected a negative relationship between Hg and capture frequency in Nelson's Sparrows (n = 315. However, MARK models detected no effect of Hg on apparent survival in any species. CONCLUSION AND SIGNIFICANCE: This study indicates that current Hg exposure places a considerable proportion of each population at risk. In particular, 52% of all sampled Saltmarsh Sparrows exhibited first primary feather Hg concentrations exceeding those associated with a >60% reduction in reproductive success in other species. This study reports evidence for net annual bioaccumulation, indicating an increased risk in older individuals. These data can be used to inform future population

  12. First gathering of Native Chiefs aboard H.M.S. 'Nelson', Port Moresby, November 5th

    OpenAIRE

    ? Angerer, C, fl 1884, photographer

    2004-01-01

    285 x 230 mm. The Reverend James Chalmers was sent out to persuade local chiefs to come on board H.M.S. 'Nelson', and here Commodore Erskine explains the meaning of the protectorate to them. He is here seen shaking hands with Boe Vagi, as he presents him with his ebony stick of authority ('rather a nice idea' Romilly remarks). The other chiefs sit on the deck, while the ship's company is gathered behind. Various national flags have been draped above the deck as awnings. Behind Erskine, i...

  13. Passageless comprehension on the Nelson-Denny reading test: well above chance for university students.

    Science.gov (United States)

    Coleman, Chris; Lindstrom, Jennifer; Nelson, Jason; Lindstrom, William; Gregg, K Noël

    2010-01-01

    The comprehension section of the Nelson-Denny Reading Test (NDRT) is widely used to assess the reading comprehension skills of adolescents and adults in the United States. In this study, the authors explored the content validity of the NDRT Comprehension Test (Forms G and H) by asking university students (with and without at-risk status for learning disorders) to answer the multiple-choice comprehension questions without reading the passages. Overall accuracy rates were well above chance for both NDRT forms and both groups of students. These results raise serious questions about the validity of the NDRT and its use in the identification of reading disabilities.

  14. The Translation Invariant Massive Nelson Model: III. Asymptotic Completeness Below the Two-Boson Threshold

    Science.gov (United States)

    Dybalski, Wojciech; Møller, Jacob Schach

    2015-11-01

    We show asymptotic completeness of two-body scattering for a class of translation invariant models describing a single quantum particle (the electron) linearly coupled to a massive scalar field (bosons). Our proof is based on a recently established Mourre estimate for these models. In contrast to previous approaches, it requires no number cutoff, no restriction on the particle-field coupling strength, and no restriction on the magnitude of total momentum. Energy, however, is restricted by the two-boson threshold, admitting only scattering of a dressed electron and a single asymptotic boson. The class of models we consider include the UV-cutoff Nelson and polaron models.

  15. Towards a construction of inclusive collision cross-sections in massless Nelson's model

    CERN Document Server

    Dybalski, Wojciech

    2011-01-01

    The conventional approach to the infrared problem in perturbative quantum electrodynamics relies on the concept of inclusive collision cross-sections. A non-perturbative variant of this notion was introduced in algebraic quantum field theory. Relying on these insights, we take first steps towards a non-perturbative construction of inclusive collision cross-sections in massless Nelson's model. We show that our proposal is consistent with the standard scattering theory in the absence of the infrared problem and discuss its status in the infrared-singular case.

  16. A short pulse, high rep-rate microdischarge VUV source

    Science.gov (United States)

    Stephens, Jacob; Fierro, Andrew; Dickens, James; Neuber, Andreas; CenterPulsed Power; Power Electronics Team

    2013-09-01

    A MOSFET based high voltage pulser is utilized to excite a microdischarge (MD), or microdischarge array (MDA) with pulsed voltages of up to 1 kV, with risetime and FWHM on the order of 10 ns and 30 ns, respectively. Additionally, the pulser is capable of pulsing at rep-rates in excess of 35 MHz. However, for these experiments the rep-rate was set on the order of 1 MHz, so as to limit excess energy deposition into the background gas and optimize the energy efficiency of VUV generation. Using VUV capable spectral diagnostics, the VUV emission of the MDs for various pressures (50-800 + Torr) and gases, focused on argon, argon-hydrogen mixtures, and neon-hydrogen mixtures (all of which provide strong emission at λ VUV emission is characterized and compared to results from transient fluid modeling of the MDA. For instance, the MDA turn-on time is recorded to be about 15 ns, which matches the full plasma development time in the model, and the MDA self- capacitance largely determines the turn-off behavior. This research was supported by an AFOSR grant on the Physics of Distributed Plasma Discharges and fellowships from the National Physical Sciences Consortium, supported by Sandia National Laboratories.

  17. 41 CFR 101-26.607 - Billings.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Billings. 101-26.607 Section 101-26.607 Public Contracts and Property Management Federal Property Management Regulations System... Defense Logistics Agency and the requisitioning activity, billings for sales will be rendered at least...

  18. Sojourner, Barnacle Bill, Yogi, & Couch

    Science.gov (United States)

    1997-01-01

    At center, Sojourner has traveled off the lander's rear ramp and onto the surface of Mars. 3D glasses are necessary to identify surface detail. The rock Barnacle Bill is to the left of Sojourner, and the large rock Yogi is at upper right. On the horizon sits the rock dubbed 'Couch.' A deflated airbag sits at lower right.The image was taken by the Imager for Mars Pathfinder (IMP) on Sol 3. The IMP is a stereo imaging system with color capability provided by 24 selectable filters -- twelve filters per 'eye.' It stands 1.8 meters above the Martian surface, and has a resolution of two millimeters at a range of two meters.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.Click below to see the left and right views individually. [figure removed for brevity, see original site] Left [figure removed for brevity, see original site] Right

  19. Alternatives for modifying the Somogyi-Nelson method for determining reducing sugars by using their thermical possibilities

    Directory of Open Access Journals (Sweden)

    Gloria Helena González Blair

    2010-03-01

    Full Text Available This article proposes modifying the Somogyi-Nelson method for determining reducing sugars, considering that sodium arsenate (one of its constituents is a toxic substance which is tending to disappear from the market. The chemical principles used in the Somogyi-Nelson method for determining reducing sugars are explained, taking those protocols proposed by Hawk et al (1954, Collmer et al (1988, Castellanos (1995 and the Universidad Nacional's Chemistry Departament (adapted from Fischer's protocol [1989] as reference. The reactions of Somogyi and Nelson's reagents are evaluated separately. The reaction between the two components and a reducing sugar is analysed and two aleternatives for modifying the method are included: the use of phosphates and that of silicates. It is proposed to substitute sodium arsenate for a phosphate in the first case and in the second for a silicate.

  20. ‘Magic Negro’, Saint or Comrade: Representations of Nelson Mandela in Film

    Directory of Open Access Journals (Sweden)

    Roger Bromley

    2014-11-01

    Full Text Available “In the late 1980s, Nelson Mandela stood alone against the apartheid state.” This comment taken from the DVD Box set cover of Nelson Mandela: From Freedom to History summarises the approach taken by many of the cinematic and televisual representations of Mandela. Linked with this is a statement by the CEO of Marriott which speaks of Mandela as “an individual who changed the arc of history through his or her singular contribution, not as a function of the era or the movement but because of what they did alone.” Together, these descriptions attempt to appropriate Mandela for a sanitised version of western individualism which sees him variously as a liberal icon, saintly hero, or the celebrity one-off “magic negro”, in Okwongo’s damning phrase taken from his magisterial valedictory piece “Mandela will never, ever be your minstrel” (Okwongo 2013. In the process, Mandela’s role in the anti-apartheid...

  1. A hermeneutical reading of Penrose and Nelson and Winter-Tracing origins of a misunderstanding?

    Directory of Open Access Journals (Sweden)

    Dr. Oliver Krone

    2010-05-01

    Full Text Available This paper aims to understand based on a hermeutical reading of Penrose (1959 and Nelson and Winter (1982 what knowledge is and where it is stored in the respective authors. Furthermore, the author wants to learn whether the subsumtion of Knowledge Integration to Knowledge Management, as it can be often in the literature, has any foundation when coming from these authors. Reason for this overall analysis is the widely held view in the discipline of Knowledge Management that these authors are forefathers for it. Based on an interpretative, qualitative approach the author examines the way in which knowledge is held and created within organisations in the main work of this pair of author. The author comes to the conclusion that the discipline of Knowledge Management has seemingly overemphasised certain elements in the work of Penrose and Nelson and Winter, while neglecting the key aspect that for both author(s the act of Knowledge Integration is much rather described in these works.

  2. Structure and function of REP34 implicates carboxypeptidase activity in Francisella tularensis host cell invasion.

    Science.gov (United States)

    Feld, Geoffrey K; El-Etr, Sahar; Corzett, Michele H; Hunter, Mark S; Belhocine, Kamila; Monack, Denise M; Frank, Matthias; Segelke, Brent W; Rasley, Amy

    2014-10-31

    Francisella tularensis is the etiological agent of tularemia, or rabbit fever. Although F. tularensis is a recognized biothreat agent with broad and expanding geographical range, its mechanism of infection and environmental persistence remain poorly understood. Previously, we identified seven F. tularensis proteins that induce a rapid encystment phenotype (REP) in the free-living amoeba, Acanthamoeba castellanii. Encystment is essential to the pathogen's long term intracellular survival in the amoeba. Here, we characterize the cellular and molecular function of REP34, a REP protein with a mass of 34 kDa. A REP34 knock-out strain of F. tularensis has a reduced ability to both induce encystment in A. castellanii and invade human macrophages. We determined the crystal structure of REP34 to 2.05-Å resolution and demonstrate robust carboxypeptidase B-like activity for the enzyme. REP34 is a zinc-containing monomeric protein with close structural homology to the metallocarboxypeptidase family of peptidases. REP34 possesses a novel topology and substrate binding pocket that deviates from the canonical funnelin structure of carboxypeptidases, putatively resulting in a catalytic role for a conserved tyrosine and distinct S1' recognition site. Taken together, these results identify REP34 as an active carboxypeptidase, implicate the enzyme as a potential key F. tularensis effector protein, and may help elucidate a mechanistic understanding of F. tularensis infection of phagocytic cells.

  3. 77 FR 32896 - Modification of Class E Airspace; Billings, MT

    Science.gov (United States)

    2012-06-04

    ... airspace at Billings Logan International Airport, Billings, MT. Controlled airspace is necessary to... Billings, MT Billings Logan International Airport, MT (Lat. 45 48'28'' N., long. 108 32'34'' W.) That... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Billings, MT AGENCY...

  4. 47 CFR 64.2401 - Truth-in-Billing Requirements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Truth-in-Billing Requirements. 64.2401 Section... (CONTINUED) MISCELLANEOUS RULES RELATING TO COMMON CARRIERS Truth-in-Billing Requirements for Common Carriers § 64.2401 Truth-in-Billing Requirements. (a) Bill organization. Telephone bills shall be clearly...

  5. Crecimiento en clavel estándar cv. Nelson, en suelo y en sustratos Crescimento de cravo estandar cv. Nelson, em solo e em substratos Growth of standard carnation cv. Nelson, in soil and substrates

    Directory of Open Access Journals (Sweden)

    Adriana Del Pilar Baracaldo Argüello

    2010-01-01

    Full Text Available El cultivo de clavel en la sabana de Bogotá ha sido importante, ya que representa en la actualidad el segundo lugar de exportación en flores de corte. Recientemente, su producción en sistema de cultivo en sustrato ha aumentado debido fundamentalmente a limitantes de tipo sanitario, por lo cual es importante el estudio del crecimiento de las plantas establecidas en este sistema de cultivo. El objetivo de este estudio fue evaluar el crecimiento del clavel estándar cv. Nelson establecido en sustratos y en suelo, a segundo pico de cosecha, para lo cual, en el SENA - Centro Multisectorial de Mosquera, plantas de clavel se sometieron a los siguientes tratamientos: 100% de cascarilla de arroz quemada; 65% cascarilla de arroz quemada - 35% fibra de coco; 35% cascarilla de arroz quemada - 65% fibra de coco y suelo. En muestreos continuos se evaluaron las variables número de hojas, longitud del tallo, diámetro de tallo, número de nudos y diámetro y longitud del botón floral y se ajustaron curvas de crecimiento. Las plantas cultivadas en el tratamiento suelo presentaron mayor número de tallos. En este tratamiento los tallos florales también presentaron un mayor número de nudos y de hojas; sin embargo, fueron más cortos. Así mismo, presentaron menor diámetro de tallo y menor longitud y diámetro del botón floral; características determinantes de la calidad. Por tanto, la producción de tallos exportables de grado "select" fue significativamente inferior en el tratamiento suelo, en comparación con los demás tratamientos.O cultivo de cravo no planalto de Bogotá tem sido importante, visto que representa, na atualidade, o segundo lugar nas exportações colombianas de flores de corte. Recentemente, sua produção em sistemas de cultivo em substrato tem aumentado em consequência de fatores sanitários. O objetivo deste estudo foi avaliar o desenvolvimento do cravo tipo estandar cv. Nelson, estabelecido em substratos e em solo, na segunda

  6. Bill McSweeney: a remembrance

    Energy Technology Data Exchange (ETDEWEB)

    Berdon, W.E.

    1999-03-01

    Pediatric radiologists (both SPR and ESPR) are a family growing in numbers. When founders such as John Caffey, Ed Neuhauser and Jacques Le Febvre died, we grieved while remembering them fondly. The death of Bill McSweeney from acute airway obstruction in August 1998 came as a shock. Yet Bill had been ill for many years. His once promising effects of been cut short by the inexorable; devastating effects of Parkinson disease and the complications of this therapy. Most current SPR and ESPR members never knew Bill McSweeney. These remembrances are designed to correct that. With 3 figs.

  7. Seis nuevas bibliotecas del Banco de la República

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    2000-05-01

    Full Text Available En febrero de 2000, el Banco de la República anunció la decisión de suspender el servicio de tesorería en algunas sucursales y reforzar las áreas culturales, convirtiendo estas últimas en bibliotecas. A partir del 1 de septiembre de 2000 se inicia la adecuación de espacios en las sucursales de Santa Marta, Sincelejo, Valledupar, Florencia y Popayán para albergar en cada una de ellas una biblioteca pública con servicios de lectura para niños y adultos; y en las bibliotecas de Girardot, Honda, Ipiales y Tunja, sucursales que contaban con servicios bibliotecarios a cargo del Banco, se amplían los espacios destinados al servicio de consulta

  8. Madison e Dahl: da república a poliarquia

    OpenAIRE

    José Alexandre Silva Junior; Dalson Britto Figueiredo Filho; Ranulfo Paranhos; Gabriel Augusto Miranda Setti; Willber Nascimento

    2014-01-01

    http://dx.doi.org/10.5007/1806-5023.2014v11n2p42 Qual é a relação entre as teorias política clássica e contemporânea? O principal objetivo desse trabalho é responder a referida questão. Em termos metodológicos, examinam-se alguns conceitos analisados por James Madison e Robert Dahl em perspectiva comparada. Em particular, o foco repousa sobre as noções madisonianas de facção, separação de poderes e república e sobre o conceito de poliarquia proposto por Dahl. Dessa maneira, descrevemos a ...

  9. Automated Production of High Rep Rate Foam Targets

    Science.gov (United States)

    Hall, F.; Spindloe, C.; Haddock, D.; Tolley, M.; Nazarov, W.

    2016-04-01

    Manufacturing low density targets in the numbers needed for high rep rate experiments is highly challenging. This report summarises advances from manual production to semiautomated and the improvements that follow both in terms of production time and target uniformity. The production process is described and shown to be improved by the integration of an xyz robot with dispensing capabilities. Results are obtained from manual and semiautomated production runs and compared. The variance in the foam thickness is reduced significantly which should decrease experimental variation due to target parameters and could allow for whole batches to be characterised by the measurement of a few samples. The work applies to both foil backed and free standing foam targets.

  10. Integral objects and Deligne's category Rep(S_t)

    CERN Document Server

    Del Padrone, Alessio

    2010-01-01

    We give negative answers to certain questions on abelian semisimple tensor categories raised by Bruno Kahn and Charles A. Weibel in connection with the preprint of Kahn "On the multiplicities of a motive" (arXiv:math/0610446), now published as Parts I and IV of "Zeta functions and motives", Pure Appl. Math. Q. 5 (2009), no. 1, part 2, 507-570. For the most interesting examples we used Deligne's category Rep(S_t,F) of representations of the "symmetric group S_t with t not an integer" with F any algebraically closed field of characteristic zero. This is an interesting family of tensor categories, "new" in some sense, interpolating the representations of the symmetric groups. Among other things we give two proofs that this category is not Schur-finite, showing hence explicitly that it is not tensor equivalent to a category of superepresentations of a supergroup.

  11. 3D Image Synthesis for B—Reps Objects

    Institute of Scientific and Technical Information of China (English)

    黄正东; 彭群生; 等

    1991-01-01

    This paper presents a new algorithm for generating 3D images of B-reps objects with trimmed surface boundaries.The 3D image is a discrete voxel-map representation within a Cubic Frame Buffer (CFB).The definition of 3D images for curve,surface and solid object are introduced which imply the connectivity and fidelity requirements.Adaptive Forward Differencing matrix (AFD-matrix) for 1D-3D manifolds in 3D space is developed.By setting rules to update the AFD-matrix,the forward difference direction and stepwise can be adjusted.Finally,an efficient algorithm is presented based on the AFD-matrix concept for converting the object in 3D space to 3D image in 3D discrete space.

  12. 75 FR 27840 - NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-05-18

    ...: 2010-11842] NUCLEAR REGULATORY COMMISSION [NRC-2010-0080] NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3...: ``NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for General... the existing guidance contained in Supplement 3 to NUREG- 0654/FEMA-REP-1, Rev. 1, ``Criteria...

  13. 75 FR 10524 - NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-03-08

    ... COMMISSION NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for... document entitled: ``NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action...-4737, or by e-mail to pdr.resource@nrc.gov . NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3,...

  14. 7 CFR 91.42 - Billing.

    Science.gov (United States)

    2010-01-01

    ... of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS SERVICES... Financial Information System (FFIS) on the 1st day, following the end of the billing cycle in...

  15. The "Naked Truth" Isn't Very Revealing: A Response to Wade Nelson on School Reform in Minnesota.

    Science.gov (United States)

    Pitton, Debra Eckerman

    1999-01-01

    A participant in Minnesota's standards-based reform initiative claims Wade Nelson, in his May 1998 "Kappan" article, is misinformed about teachers' exclusion from this movement. The standards constitute a minimal competence level in reading, math, and writing, were developed cooperatively, and have raised teacher expectations of…

  16. Romance and Freedom: Nelson and Winnie Mandela’s Politics of Gender in Three Post-Apartheid Novels

    Directory of Open Access Journals (Sweden)

    Lorenzo Mari

    2014-11-01

    Full Text Available This paper aims to retrace the influence of the politics of gender enacted by Nelson and Winnie Mandela on post-apartheid gender relationships, as represented in three novels: Phaswane Mpe’s Welcome to Our Hillbrow (2001, Njabulo Ndebele’s The Cry of Winnie Mandela (2003 and Lewis Nkosi’s Mandela’s Ego (2006.Recently, Nelson and Winnie Mandela’s marriage has been also described as the “unusual founding-family romance” (Munro 2014 of the post-apartheid nation. Their marriage lasted from 1958 to 1992, including, thus, the last decades of the anti-apartheid struggle, as well as the demise of the apartheid regime. Their separation, which was due in the first place to Nelson Mandela’s imprisonment and, later, to their divorce, eventually marked the disruption of this founding-family romance, making it “unusual”.As a consequence, the deconstructive take on Nelson Mandela’s fatherhood and masculinity and Winnie Mandela’s femininity and motherhood which is enacted in the three novels also allows to reassess the possibility of that “founding-family romance”, envisioning an alternative understanding of the origins of the post-apartheid South African nation.

  17. Mixing and photoreactivity of dissolved organic matter in the Nelson/Hayes estuarine system (Hudson Bay, Canada)

    Science.gov (United States)

    Guéguen, C.; Mokhtar, M.; Perroud, A.; McCullough, G.; Papakyriakou, T.

    2016-09-01

    This work presents the results of a 4-year study (2009-2012) investigating the mixing and photoreactivity of dissolved organic matter (DOM) in the Nelson/Hayes estuary (Hudson Bay). Dissolved organic carbon (DOC), colored DOM, and humic-like DOM decreased with increasing salinity (r2 = 0.70-0.84). Removal of DOM was noticeable at low to mid salinity range, likely due to degradation and/or adsorption to particles. DOM photobleaching rates (i.e., decrease in DOM signal resulting from exposure to solar radiation) ranged from 0.005 to 0.030 h- 1, corresponding to half-lives of 4.9-9.9 days. Dissolved organic matter from the Nelson and Hayes Rivers was more photoreactive than from the estuary where the photodegradation of terrestrial DOM decreased with increasing salinity. Coincident with the loss of CDOM absorption was an increase in spectral slope S, suggesting a decrease in DOM molecular weight. Marked differences in photoreactivity of protein- and humic-like DOM were observed with highly humidified material being the most photosensitive. Information generated by our study will provide a valuable data set for better understanding the impacts of future hydroelectric development and climate change on DOM biogeochemical dynamics in the Nelson/Hayes estuary and coastal domain. This study will constitute a reference on terrestrial DOM fate prior to building additional generating capacity on the Nelson River.

  18. Commentary: The Development of Hippocampal-Dependent Memory Functions: Theoretical Comments on Jabès and Nelson Review (2015)

    Science.gov (United States)

    Bachevalier, Jocelyne

    2015-01-01

    Studies investigating the development of memory processes and their neural substrates have flourished over the past two decades. The review by Jabès and Nelson (2015) adds an important piece to our understanding of the maturation of different elements and circuits within the hippocampal system and their association with the progressive development…

  19. GESTÃO INOVADORA DE PROJETOS E ESTUDO DE CASO DE CONTROLE DE EMPREENDIMENTO: NELSON MANDELA BAY METROPOLE – ÁFRICA DO SUL

    Directory of Open Access Journals (Sweden)

    Daniel De Witt Koen

    2010-12-01

    Full Text Available Uma pesquisa Intensiva com os usuários finais no setor da Habitação Econômica da República Sul-Africana tornou-se necessário para encontrar formas de enfrentar o contínuo aumento dos custos e ainda continuar a satisfazer as preferências, com qualidade e acessibilidade. A pesquisa tem de ser sucedida por projetos inovadores e métodos construtivos rápidos e de baixo custo, sem perder qualidade e estética. Os custos de terreno e o adensamento dos projetos, em equilíbrio com a qualidade ambiental, tornaram-se de enorme importância em qualquer empreendimento sustentável. O mesmo se aplica às vizinhanças, quanto à revitalização dos bairros. Um exemplo típico é o Nelson Mandela Bay Metropole na África do Sul, onde 100.000 unidades habitacionais precisam ser construídas em um período de três a cinco anos para acabar com o déficit. A quantidade de dados relativos a uma única habitação é vasta e, em um grande empreendimento, ainda mais significativa. Tradicionalmente, os dados são armazenados em vários locais, por exemplo, com autoridades governamentais, arquitetos ou outros profissionais, empreendedores, subcontratados, agentes imobiliários, instituições financeiras ou proprietários. Baixa eficiência e atrasos substanciais são o resultado, quando os dados existentes não podem ser acessados rapidamente, ou não são encontrados. Um processo de localização espacial e sistema de controle de dados física e inequivocamente associado com cada particular unidade habitacional foi desenvolvido para resolver com sucesso a maioria desses problemas.

  20. [A life among insects and books: an interview with Nelson Papavero].

    Science.gov (United States)

    Klassa, Bruna; Santos, Charles Morphy D

    2012-12-01

    Nelson Papavero is one of the top representatives of Brazilian zoology. His decisive contributions to this science began in the second half of the twentieth century, when he started publishing in the areas of zoology, systematics, biogeography, and the history of science while also working at graduate courses and training teachers and students. He was key to the introduction of Hennig's phylogenetic systematics in Brazil and its chief advocate. His active participation in the creation of the Special Courses on Zoological Systematics within the National Council for Scientific and Technological Development and his work at numerous administrative posts which he held during his academic career were vital to the development of zoology and comparative biology in Brazil. His endeavors also reached into other Latin American countries, like Mexico and Argentina.

  1. "Passageless" administration of the Nelson-Denny Reading Comprehension Test: associations with IQ and reading skills.

    Science.gov (United States)

    Ready, Rebecca E; Chaudhry, Maheen F; Schatz, Kelly C; Strazzullo, Sarah

    2013-01-01

    There are few tests that assess reading comprehension in adults, but these tests are needed for a comprehensive assessment of reading disorders (RD). The Nelson-Denny Reading Test (NDRT) has a long-passage reading comprehension component that can be used with adolescents and adults. A problem with the NDRT is that reading comprehension test items can be answered correctly without reading the associated passage. The current study determined how IQ, verbal comprehension, and reading skills were associated with scores on a passageless administration of the NDRT. Results indicated that IQ, verbal comprehension, and broad reading skills were significantly associated with greater NDRT passageless scores. Results raise questions about the validity of the reading comprehension component of the NDRT and suggest that the test may have differential validity based on individual differences in vocabulary, general fund of knowledge, and broad reading skills.

  2. Morte e religião em "Rio dos Bons Sinais", de Nelson Saúte

    OpenAIRE

    Nogueira, Isabel Margarida da Silva Marques

    2012-01-01

    Neste trabalho pretende-se apresentar uma perspectiva, centrada nas representações da morte e da religião, dos contos que integram a obra “Rio dos Bons Sinais”, de Nelson Saúte. Será ainda feita uma breve apresentação do autor, das possíveis razões subjacentes à escolha do conto como forma narrativa privilegiada, e um breve olhar à realidade moçambicana pós-colonial. Como os contos têm a morte e os seus rituais como linha unificadora, serão também apresentadas algumas considerações sobre a vi...

  3. Estudio comparativo del spray Nelson d3000 a diferentes alturas en condiciones aisladas

    OpenAIRE

    Esequiel Rolando Jiménez E.; Miguel Domínguez G.

    2008-01-01

    En el presente artículo se caracteriza el emisor de tipo spray Nelson D3000. Se explica el procedimiento para realizar las evaluaciones a 1 y 2 m de altura a modo comparativo, donde se determina el coeficiente de uniformidad de Christiansen (CuC), intensidad de aplicación de agua (Ia) y diámetro de cobertura efectivo (De), además de analizar el patrón de distribución mediante mapas. Los resultados arrojaron menores valores de Ia (4.22 mm/h) y CuC (6.80%) a 2 m de colocación respecto al suelo,...

  4. Revisiting the Nelson-Morfey scaling law for flow noise from duct constrictions

    Science.gov (United States)

    Kårekull, Oscar; Efraimsson, Gunilla; Åbom, Mats

    2015-11-01

    The semi-empirical scaling law by Nelson and Morfey [1] predicts the noise generation from constrictions in ducts with low Mach number flows. The results presented here demonstrate that the original model loses accuracy for constrictions of high pressure loss. A generalization based on a momentum flux assumption of the dipole forces is suggested and is evaluated against measurement results for orifice geometries of higher pressure loss than earlier evaluated. A prediction model including constrictions at flow duct terminations is also suggested. Improved accuracy for the predictions of the new model is found for orifice geometries of high pressure loss inside and at the end of ducts. The extended model is finally evaluated by measurements on a regular ventilation air terminal device.

  5. Nelson Rodrigues e o Rio de Janeiro: memórias de um passional

    Directory of Open Access Journals (Sweden)

    Ângela Maria Dias

    2005-06-01

    Full Text Available A crônica de Nelson Rodrigues, ao ser escrita do ponto de vista do homem comum - no diapasão do "pobre-diabo de um terno só" -, propicia a fundação de uma voz fronteiriça, entre o banal e o singular, e realiza a profissão de fé antiintelectualista e anti-retórica, característica da obra em suas diversas modalidades. A cidade do Rio de Janeiro, vitrine do Brasil durante as décadas de 1960 e 1970, constitui o protagonista do texto e opera a linguagem de modo a recriar seus espaços. O artista desdobra a sua imaginação totalizante em opostas e simétricas dimensões, a pornográfica e a mística, ou a do erotômano e a do "convertido". A dramatização pública do "reacionário" constitui, então, a resposta ritualística e sacrificial ao "revolucionário de esquerda" dos anos 1960, na prática renovada das formas totalizantes de pensamento.La crónica de Nelson Rodrigues, escrita del punto de vista del hombre común - en el disyuntiva del "pobre-hombre de traje único" - propicia la fundación de una voz fronteriza, entre lo banal y lo singular, y realiza la profesión de fé antiintelectualista y antirretórica, característica de la obra, en sus diversas modalidades. Rio de Janeiro, ciudad escaparate de Brasil durante las décadas de los 60 y 70, constituye el protagonista del texto y opera el lenguaje de modo a recriar sus espacios. El artista desdobla su imaginación totalizante en opuestas y simétricas dimensiones, la pornográfica y la mística, o la del erotómano y la del "convertido". La dramatización pública del "reacccionario" constituye, entonces, la respuesta del ritual y del sacrifício al "revolucionario de izquierda" de los años 60, en la práctica renovada de las formas totalizantes de pensamiento.Written from the point of view of the common man, Nelson Rodrigues' chronicle founds a bordering voice between the trivial and the singular and realizes an antiintellectualistic profession of faith. The city of Rio de

  6. The Mass Shell of the Nelson Model without Cut-Offs

    CERN Document Server

    Bachmann, S; Pizzo, A

    2011-01-01

    The massless Nelson model describes non-relativistic, spinless quantum particles interacting with a relativistic, massless, scalar quantum field. The interaction is linear in the field. We analyze the one particle sector. First, we construct the renormalized mass shell of the non-relativistic particle for an arbitrarily small infrared cut-off that turns off the interaction with the low energy modes of the field. No ultraviolet cut-off is imposed. Second, we implement a suitable Bogolyubov transformation of the Hamiltonian in the infrared regime. This transformation depends on the total momentum of the system and is non-unitary as the infrared cut-off is removed. For the transformed Hamiltonian we construct the mass shell in the limit where both the ultraviolet and the infrared cut-off are removed. Our approach is constructive and leads to explicit expansion formulae which are amenable to rigorously control the S-matrix elements.

  7. STRESS MONITORING OF MULBERRY PLANTS BY FINDING REP USING HYPERSPECTRAL DATA

    Directory of Open Access Journals (Sweden)

    K. Bhosle

    2017-05-01

    Full Text Available Stressed on crop can be monitored using different indices. Red Edge position is good estimator for stress monitoring. The red edge position (REP is strongly correlated with foliar chlorophyll content. Strong chlorophyll absorption causes the abrupt change in the 680–800 nm region of reflectance spectra of green vegetation. The red edge consist the point of maximum slope between red and near-infrared wavelengths. REP can be used to recognize green zone of the observation area. The REP is present in spectra for vegetation recorded by remote sensing methods. REP is clearer and significant in hyper spectral data as hyper spectral consist of more and continuous bands data. In this paper experiments were carried out for mulberry crop using USGS EO-1 Hyperion data. Atmospheric corrected data is used for classification. Classification is carried out on small cluster of 14 field samples. Ground truth is verified and classified by comparing with Hyperion data. REP is different for different stressed condition of crops and shows healthy and diseased crop condition. Nutritional stresses, diseases, drought of plants are detected using REP. Stressed and healthy field of mulberry are estimated by calculating REP using maximum first derivative, linear interpolation, linear extrapolation method. Finally REP is compared using above methods. It is noticeable difference of REP for healthy and stressed crop. The research indicates that overall accuracy using maximum first derivative was 92.85 % and it was more compared to other methods. Linear extrapolation gives less accuracy compared to linear interpolation method.

  8. Two families of rep-like genes that probably originated by interspecies recombination are represented in viral, plasmid, bacterial, and parasitic protozoan genomes.

    Science.gov (United States)

    Gibbs, Mark J; Smeianov, Vladimir V; Steele, James L; Upcroft, Peter; Efimov, Boris A

    2006-06-01

    Two families of genes related to, and including, rolling circle replication initiator protein (Rep) genes were defined by sequence similarity and by evidence of intergene family recombination. The Rep genes of circoviruses were the best characterized members of the "RecRep1 family." Other members of the RecRep1 family were Rep-like genes found in the genomes of the Canarypox virus, Entamoeba histolytica, and Giardia duodenalis and in a plasmid, p4M, from the Gram-positive bacterium, Bifidobacterium pseudocatenulatum. The "RecRep2 family" comprised some previously identified Rep-like genes from plasmids of phytoplasmas and similar Rep-like genes from the genomes of Lactobacillus acidophilus, Lactococcus lactis, and Phytoplasma asteris. Both RecRep1 and RecRep2 proteins have a nucleotide-binding domain significantly similar to the helicases (2C proteins) of picorna-like viruses. On the N-terminal side of the nucleotide binding domain, RecRep1 proteins have a domain significantly similar to one found in nanovirus Reps, whereas RecRep2 proteins have a domain significantly similar to one in the Reps of pLS1 plasmids. We speculate that RecRep genes have been transferred from viruses or plasmids to parasitic protozoan and bacterial genomes and that Rep proteins were themselves involved in the original recombination events that generated the ancestral RecRep genes.

  9. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68.

    Directory of Open Access Journals (Sweden)

    Jorge Mansilla-Soto

    2009-07-01

    Full Text Available Rep68 is a multifunctional protein of the adeno-associated virus (AAV, a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific integration of the AAV genome into human chromosome 19. Rep68 is a member of the superfamily 3 (SF3 helicases, along with the well-studied initiator proteins simian virus 40 large T antigen (SV40-LTag and bovine papillomavirus (BPV E1. Structurally, SF3 helicases share two domains, a DNA origin interaction domain (OID and an AAA(+ motor domain. The AAA(+ motor domain is also a structural feature of cellular initiators and it functions as a platform for initiator oligomerization. Here, we studied Rep68 oligomerization in vitro in the presence of different DNA substrates using a variety of biophysical techniques and cryo-EM. We found that a dsDNA region of the AAV origin promotes the formation of a complex containing five Rep68 subunits. Interestingly, non-specific ssDNA promotes the formation of a double-ring Rep68, a known structure formed by the LTag and E1 initiator proteins. The Rep68 ring symmetry is 8-fold, thus differing from the hexameric rings formed by the other SF3 helicases. However, similiar to LTag and E1, Rep68 rings are oriented head-to-head, suggesting that DNA unwinding by the complex proceeds bidirectionally. This novel Rep68 quaternary structure requires both the DNA binding and AAA(+ domains, indicating cooperativity between these regions during oligomerization in vitro. Our study clearly demonstrates that Rep68 can oligomerize through two distinct oligomerization pathways, which depend on both the DNA structure and cooperativity of Rep68 domains. These findings provide insight into the dynamics and oligomeric adaptability of Rep68 and serve as a step towards understanding the role of this multifunctional protein during AAV DNA replication and site-specific integration.

  10. Madison e Dahl: da república a poliarquia

    Directory of Open Access Journals (Sweden)

    José Alexandre Silva Junior

    2014-12-01

    Full Text Available http://dx.doi.org/10.5007/1806-5023.2014v11n2p42 Qual é a relação entre as teorias política clássica e contemporânea? O principal objetivo desse trabalho é responder a referida questão. Em termos metodológicos, examinam-se alguns conceitos analisados por James Madison e Robert Dahl em perspectiva comparada. Em particular, o foco repousa sobre as noções madisonianas de facção, separação de poderes e república e sobre o conceito de poliarquia proposto por Dahl. Dessa maneira, descrevemos a continua influência de certos aspectos próprios da teoria política clássica no modo como a teoria contemporânea lida com o tema. Concluímos que a contribuição dos autores clássicos permite que a teoria política contemporânea seja capaz de tentar oferecer explicações mais robustas aos “novos” problemas enfrentados pela disciplina.

  11. Paradoxo e natureza no livro V da República

    Directory of Open Access Journals (Sweden)

    Marcelo P. Marques

    2010-12-01

    Full Text Available O artigo analisa a primeira onda do livro V da República de Platão, levando em conta a oposição entre opinião (dóxa e ciência (epistéme, só formulada ao final da terceira onda. Sócrates problematiza a opinião corrente que aceita a diferença de natureza entre homens e mulheres para avançar a ideia de uma natureza humana comum. É essa tese paradoxal que justifica que possam ter uma mesma educação e que, assim, possam desempenhar as mesmas funções, vindo a ser guardiões e governantes da cidade.The paper analyses the first wave in Plato´s Republic V, taking into account the opposition between opinion (doxa and science (episteme, formulated at the end of the third wave. Socrates questions the current opinion which accepts the difference in nature between men and women in order to propose the idea of a common human nature. It is this paradoxical thesis that justifies the proposal that all should have the same education, thus allowing them to fulfill the same functions and, eventually, to become guardians and rulers in the city.

  12. China - 60 anos de República Popular

    Directory of Open Access Journals (Sweden)

    Wladimir Pomar

    2009-10-01

    Full Text Available Em dezembro de 1949, após mais de 23 anos de guerras, tanto civis, quanto de resistência contra a agressão japonesa, a China assistiu à fundação da República Popular, com a vitória do Exército Popular de Libertação, tendo à frente o Partido Comunista, sobre os exércitos comandados pelo Guomindang.

  13. Euclides da Cunha e a República

    Directory of Open Access Journals (Sweden)

    Roberto Ventura

    1996-04-01

    Full Text Available A revisão da República é central na obra de Euclides da Cunha, presente em seus artigos de jornal e na maior parte de seus livros. Analisou o regime republicano não só em Os sertões (1902, em que tratou da guerra de Canudos, como em Contrastes e confrontos (1907 e em Á margem da história (1909. Foi testemunha e intérprete dos rumos do novo regime, que ajudara a fundar com artigos de propaganda política no jornal A Província de S. Paulo.The revision of the Republic is a central concern in the works of Euclides da Cunha. It appears in his newspaper articles and in most of his books. He analysed the republican regime not only in Os sertões (Rebellion in the backlands, 1902, in which he deals with the Canudos War, but also in Contrastes e confrontos (1907 and in À margem da história (1909. He both witnessed and interpreted the trends of the new regime which he had helped to set up with his political articles in the newspaper A Província de S. Paulo.

  14. Hariduspoliitikas ilmnevad üksmeele märgid / Mailis Reps

    Index Scriptorium Estoniae

    Reps, Mailis, 1975-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 7. juuni lk. 2, Nädaline 10. juuni lk. 2. Haridusminister Mailis Reps Res Publica ja Isamaaliidu ühisest haridusprogrammist ning juba teostumas hariduspoliitilistest eesmärkidest

  15. Reps sai Narvas tõrjuva vastuvõtu osaliseks / Tanel Mazur

    Index Scriptorium Estoniae

    Mazur, Tanel, 1971-

    2005-01-01

    Selle aasta koolirahu kuulutati välja Narva linnuses, rongkäigus osalesid Narva koolide õpilaste hulgas ka üle 1300 teistest piirkondadest saabunud õpilase. Tervituskõnega esines haridus- ja teadusminister Mailis Reps

  16. 42 CFR 460.110 - Bill of rights.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Bill of rights. 460.110 Section 460.110 Public...) Participant Rights § 460.110 Bill of rights. (a) Written bill of rights. A PACE organization must have a written participant bill of rights designed to protect and promote the rights of each participant. Those...

  17. What Every Student Should Know about the Bill of Rights.

    Science.gov (United States)

    Petracca, Mark P.

    1990-01-01

    Traces the history of the Bill of Rights. Delineates the early arguments proposed for and against the Bill of Rights. Discusses the recent Ronald Reagan-Edwin Meese attack on the applicability of the Bill of Rights. Identifies seven items that every student should know about the Bill of Rights. (RW)

  18. The Filament-specific Rep1-1 Repellent of the Phytopathogen Ustilago maydis Forms Functional Surface-active Amyloid-like Fibrils

    NARCIS (Netherlands)

    Teertstra, Wieke R.; van der Velden, Gisela J.; de Jong, Jan F.; Kruijtzer, John A. W.; Liskamp, Rob M. J.; Kroon-Batenburg, Loes M. J.; Muller, Wally H.; Gebbink, Martijn F. B. G.; Wosten, Han A. B.

    2009-01-01

    Repellents of the maize pathogen Ustilago maydis are involved in formation of hydrophobic aerial hyphae and in cellular attachment. These peptides, called Rep1-1 to Rep1-11, are encoded by the rep1 gene and result from cleavage of the precursor protein Rep1 during passage of the secretion pathway. U

  19. The Filament-specific Rep1-1 Repellent of the Phytopathogen Ustilago maydis Forms Functional Surface-active Amyloid-like Fibrils

    NARCIS (Netherlands)

    Teertstra, Wieke R.; van der Velden, Gisela J.; de Jong, Jan F.; Kruijtzer, John A. W.; Liskamp, Rob M. J.; Kroon-Batenburg, Loes M. J.; Muller, Wally H.; Gebbink, Martijn F. B. G.; Wosten, Han A. B.

    2009-01-01

    Repellents of the maize pathogen Ustilago maydis are involved in formation of hydrophobic aerial hyphae and in cellular attachment. These peptides, called Rep1-1 to Rep1-11, are encoded by the rep1 gene and result from cleavage of the precursor protein Rep1 during passage of the secretion pathway. U

  20. Red-billed Leiothrix (Leiothrix lutea)

    Science.gov (United States)

    Male, Timothy D.; Fancy, Steven G.; Ralph, C. John

    1998-01-01

    Known in the cage bird trade as the Japanese Hill-Robin, Peking Robin, or Peking Nightingale, the Red-billed Leiothrix was first imported into the Hawaiian Islands in 1911 ( Fisher and Baldwin 1947 ), with intentional releases to the wild occurring after 1918 ( Caum 1933 ). A native of Southeast Asia, southern China, and the Himalayan regions of India, this species is a medium-sized, green and yellow babbler with a conspicuous red bill and strongly notched tail. The species is extremely active, but individuals are somewhat secretive and difficult to see as they flit around in the understory, often in small groups. The Red-billed Leiothrix is found in a wide variety of habitats in the Hawaiian Islands, including both native and exotic forests from sea level to near mountain summits exceeding 4,000 m elevation.

  1. Nelson-Siegel Model Is Applied by Constitution of National Debt Yield Curve%Nelson-Siegel模型在国债收益率曲线构造中的应用

    Institute of Scientific and Technical Information of China (English)

    范周田; 刘乐勇; 黄裕荣

    2009-01-01

    为了给中国当前的货币政策提供一个准确的依据,在用样条法拟合国债收益率曲线的基础上,用Nelson-Siegel模型拟合了国债收益率曲线,并对原始到期收益率出现的短期收益率高于长期收益率的反向形态以及国家宏观经济政策和微观市场环境的原因使长期收益率高于短期收益率的正向趋势进行了实证分析.通过对模型稳定性进行比较,得出Nelson-Siegel模型比较适用于构造我国国债收益率曲线.

  2. Utopian dream: a new farm bill.

    Science.gov (United States)

    Nestle, Marion

    2012-01-01

    In the fall of 2011, I taught a graduate food studies course at New York University devoted to the farm bill, a massive and massively opaque piece of legislation passed most recently in 2008 and up for renewal in 2012. The farm bill supports farmers, of course, but also specifies how the United States deals with such matters as conservation, forestry, energy policy, organic food production, international food aid, and domestic food assistance. My students came from programs in nutrition, food studies, public health, public policy, and law, all united in the belief that a smaller scale, more regionalized, and more sustainable food system would be healthier for people and the planet.

  3. Comparison of a commercially available rep-PCR system (Diversilab(R)) with PCR-ribotyping for typing of Clostridium difficile strains.

    OpenAIRE

    Eckert, C.; van Broeck, Johan; Spigaglia, P.; Burghoffer, B; Delmée, Michel; Mastrantonio, P; Barbut, F

    2011-01-01

    This study compared a rep-PCR method (DiversiLab® system) to PCR-ribotyping. The discriminatory power of rep-PCR was 0.997. Among the PCR-ribotype 027, different rep-types could be distinguished. Rep-PCR showed a higher discriminatory power than PCR-ribotyping. Nevertheless, this method requires technical skill and visual interpretation of rep-PCR fingerprint patterns may be difficult.

  4. 基于Nelson-Siegel模型预测中债国债收益率曲线形态

    Institute of Scientific and Technical Information of China (English)

    郭济敏; 张嘉为

    2016-01-01

    本文探讨了基于Nelson-Siegel模型拟合中债国债即期收益率曲线的有效性问题,并分析了模型参数的经济意义;通过对比多个收益率预测模型,发现基于Nelson-Siegel模型的预测效果要好于单纯的随机游走和时间序列模型.最后,本文依此方法对2016年6月至12月的中债收益率曲线形态和关键期限的月收益率进行了预测.

  5. Metal-Induced Stabilization and Activation of Plasmid Replication Initiator RepB

    Science.gov (United States)

    Ruiz-Masó, José A.; Bordanaba-Ruiseco, Lorena; Sanz, Marta; Menéndez, Margarita; del Solar, Gloria

    2016-01-01

    Initiation of plasmid rolling circle replication (RCR) is catalyzed by a plasmid-encoded Rep protein that performs a Tyr- and metal-dependent site-specific cleavage of one DNA strand within the double-strand origin (dso) of replication. The crystal structure of RepB, the initiator protein of the streptococcal plasmid pMV158, constitutes the first example of a Rep protein structure from RCR plasmids. It forms a toroidal homohexameric ring where each RepB protomer consists of two domains: the C-terminal domain involved in oligomerization and the N-terminal domain containing the DNA-binding and endonuclease activities. Binding of Mn2+ to the active site is essential for the catalytic activity of RepB. In this work, we have studied the effects of metal binding on the structure and thermostability of full-length hexameric RepB and each of its separate domains by using different biophysical approaches. The analysis of the temperature-induced changes in RepB shows that the first thermal transition, which occurs at a range of temperatures physiologically relevant for the pMV158 pneumococcal host, represents an irreversible conformational change that affects the secondary and tertiary structure of the protein, which becomes prone to self-associate. This transition, which is also shown to result in loss of DNA binding capacity and catalytic activity of RepB, is confined to its N-terminal domain. Mn2+ protects the protein from undergoing this detrimental conformational change and the observed protection correlates well with the high-affinity binding of the cation to the active site, as substituting one of the metal-ligands at this site impairs both the protein affinity for Mn2+and the Mn2+-driven thermostabilization effect. The level of catalytic activity of the protein, especially in the case of full-length RepB, cannot be explained based only on the high-affinity binding of Mn2+ at the active site and suggests the existence of additional, lower-affinity metal binding site

  6. Attentiography of the Body: correlations between Lisa Nelson and Gilbert Simondon’s work from a narrative fragment

    Directory of Open Access Journals (Sweden)

    Francisco de Assis Gaspar Neto

    2017-01-01

    Full Text Available The paper suggests an interconnection between art and philosophy through approaching the practice of attention upon a section of Tuning Scores, described by the American choreographer and videomaker Lisa Nelson and the individual’s relationship with the environment and with others thought by the French philosopher Gilbert Simondon. Lisa Nelson’s fragment describing the Attentiography of Body is presented in conjunction with Simondon’s characters by covering some interpersonal relationship traits: individuation, individuality, and personality.

  7. Getting there: Extended drilling season, arrival of giants spells coming of age in Fort Nelson, B.C.

    Energy Technology Data Exchange (ETDEWEB)

    Stonehouse, D.

    2004-06-07

    Activities in the Fort Nelson area, located at Mile 300 of the Alaska Highway in the rugged northeastern corner of British Columbia, in terms of exploration, drilling and construction of pipelines and gas gathering systems, are discussed. The current natural gas boom began in 2002 when EnCana announced the acquisition of a massive land position in the Greater Sierra Region just east of Fort Nelson. The company claims that its 4,200 square miles of land contains five trillion cubic feet of sweet gas, at least half of which is recoverable. The company expects to drill between 150 to 200 wells a year to produce the gas. To date the company has drilled some 500 wells, and is producing more than 215 million cubic feet of gas per day from the Greater Sierra field. Targeting all depths and formation types on its 4,200 square miles holdings EnCana expects the area to supply stable production for at least 30 years. With development moving at a feverish pace, industry estimates that there could be as many as 10,000 workers living in and working around Fort Nelson during the peak of winter activity. The business community includes more than 200 that are related directly to the oil and gas sector. All this activity creates many challenges; housing, with prices climbing to levels seen only in urban centres like Calgary, being just one of them. However, with natural gas prices forecast to remain strong long into the future, Fort Nelson's future prospects are considered safe and secure for a long time to come. The bright prospects for the foreseeable future notwithstanding, the community is already planning for the time when the gas runs out. An overview of some of these plans, one of which involves development of a wildlife reserve as a tourist attraction, and another which proposes the construction of a rail extension as a launching point for industry to expand further north, is provided.

  8. Modalidades da decadência: doenças, deformidades e médicos no teatro de Nelson Rodrigues

    Directory of Open Access Journals (Sweden)

    Adriano de Paula Rabelo

    2012-10-01

    Full Text Available This article approaches the way through which Nelson Rodrigues depicts disease, deformity and doctors in his theatrical works. Starting from a brief trajectory of the grotesque as a concept and presenting the playwright’s world vision, this text analyses how illness and peformation are shown in his plays, as well as the professionals who treat them. Finally, it reflects on the reasons and purposes of grotesque in Rodrigues’ works.

  9. 开普敦Behnond Mount Nelson Hotel以全新面貌再度登场

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    著名度假胜地Bdmond Mount Nelson Hotel位于充满活力的开普敦核心地带,其洋溢历史气息的Helmsley翼楼套房及备受喜爱的花园平房经室内设计公司Champalinmud重新打造后,已于近期再度登场。

  10. "Buffalo Bill" and the Siouan Image.

    Science.gov (United States)

    Rogers, Phyllis

    1983-01-01

    The popular art of William F. "Buffalo Bill" Cody--lithographic posters advertising his Wild West Show and depicting the Indians who performed in it--created the visual image of the American Indian that we have come to know as the Siouan stereotype. By contrast the artists' images of the American Indian were inaccessible to the general…

  11. The Balanced Billing Cycle Vehicle Routing Problem

    Energy Technology Data Exchange (ETDEWEB)

    Groer, Christopher S [ORNL; Golden, Bruce [University of Maryland; Edward, Wasil [American University

    2009-01-01

    Utility companies typically send their meter readers out each day of the billing cycle in order to determine each customer s usage for the period. Customer churn requires the utility company to periodically remove some customer locations from its meter-reading routes. On the other hand, the addition of new customers and locations requires the utility company to add newstops to the existing routes. A utility that does not adjust its meter-reading routes over time can find itself with inefficient routes and, subsequently, higher meter-reading costs. Furthermore, the utility can end up with certain billing days that require substantially larger meter-reading resources than others. However, remedying this problem is not as simple as it may initially seem. Certain regulatory and customer service considerations can prevent the utility from shifting a customer s billing day by more than a few days in either direction. Thus, the problem of reducing the meterreading costs and balancing the workload can become quite difficult. We describe this Balanced Billing Cycle Vehicle Routing Problem in more detail and develop an algorithm for providing solutions to a slightly simplified version of the problem. Our algorithm uses a combination of heuristics and integer programming via a three-stage algorithm. We discuss the performance of our procedure on a real-world data set.

  12. Psychiatric Rehabilitation: A Dialogue with Bill Anthony.

    Science.gov (United States)

    Livneh, Hanoch

    1984-01-01

    Presents an interview with Dr. Bill Anthony, Director of the Boston University Center for Rehabilitation Research and Training in Mental Health. Outlines the historical forerunners of Anthony's Psychiatric Rehabilitation Model, describes its major components, discusses its applicability to different client populations, and demonstrates the model's…

  13. Perkins Bill is Approved by Congress

    Science.gov (United States)

    Cavanagh, Sean

    2006-01-01

    Career and technical education programs will face new pressure to show that they are academically rigorous and guiding high school students through a lineup of courses that prepares them for college or the workplace, under a bill approved by Congress. The reauthorization of the federal law known as the Perkins Act--dealing with what traditionally…

  14. Electoral (Amendment) (Hours of Polling) Bill 2013

    DEFF Research Database (Denmark)

    Butler, Graham; Hunt, Brian; Doyle, Andrew

    2013-01-01

    Private Members' Bill (legislation) introduced in Dáil Éireann (House of Deputies), Houses of the Oireachtas (Parliament of Ireland). An Act to set voting hours for Dáil Elections, Dáil Bye-Elections, Presidential Elections, European Parliament Elections, Local Government Elections and Referenda...

  15. Bill Gates,Head of Microsoft

    Institute of Scientific and Technical Information of China (English)

    徐鸿钧

    2001-01-01

    As a teenager in 1972, Bill Gates once said that he would be a millionaire by the time he was 20. Only 15 years later he was a billionaire. And by 1992, as head of the Microsoft company,he became the richest man in America with assets(资产) ofabout US$ 6. 3 billion.

  16. Is Bill Gates Getting Too Powerful?

    Institute of Scientific and Technical Information of China (English)

    郑娟娟

    2004-01-01

    Plenty of technology genius lie awake nights anxiously wondering what Bill Gates is up to and how to grow up to be just like him. Microsoft, the company he heads, already owns the operating systems that run most of the world's personal computers. But good comput-

  17. A Dimeric Rep Protein Initiates Replication of a Linear Archaeal Virus Genome: Implications for the Rep Mechanism and Viral Replication ▿ †

    Science.gov (United States)

    Oke, Muse; Kerou, Melina; Liu, Huanting; Peng, Xu; Garrett, Roger A.; Prangishvili, David; Naismith, James H.; White, Malcolm F.

    2011-01-01

    The Rudiviridae are a family of rod-shaped archaeal viruses with covalently closed, linear double-stranded DNA (dsDNA) genomes. Their replication mechanisms remain obscure, although parallels have been drawn to the Poxviridae and other large cytoplasmic eukaryotic viruses. Here we report that a protein encoded in the 34-kbp genome of the rudivirus SIRV1 is a member of the replication initiator (Rep) superfamily of proteins, which initiate rolling-circle replication (RCR) of diverse viruses and plasmids. We show that SIRV Rep nicks the viral hairpin terminus, forming a covalent adduct between an active-site tyrosine and the 5′ end of the DNA, releasing a 3′ DNA end as a primer for DNA synthesis. The enzyme can also catalyze the joining reaction that is necessary to reseal the DNA hairpin and terminate replication. The dimeric structure points to a simple mechanism through which two closely positioned active sites, each with a single tyrosine residue, work in tandem to catalyze DNA nicking and joining. We propose a novel mechanism for rudivirus DNA replication, incorporating the first known example of a Rep protein that is not linked to RCR. The implications for Rep protein function and viral replication are discussed. PMID:21068244

  18. Use of Tephrochronology in the Evaluation of Accumulation Rates on Nelson Ice Cap,South Shetland Isands,Antarctica

    Institute of Scientific and Technical Information of China (English)

    秦大河; G A.Zielinski; M.S.Germain; 任贾文; 王晓香; 王文悌

    1994-01-01

    A volcanic ash layer was observed in the 3 ice cores on the Nelson Ice Cap,Antarctica.Acomparison of major elemental composition of glass shards from the 3 tephra layers with average whole-rockcompositions of 1967-1970 eruptions on the Deception Island and of glass shards from other suspected De-ception Island eruptions collected from Antarctic ice and firn indicate that the most reasonable source for thetephra in the Nelson Ice Cap cores is the 1970 eruption on the Deception Island.From the depth of the vol-canic ash layer and measured density profile of the cores,the net accumulation rate at the summit,CoreGW,is 1200 g·cm-2·a-1 during the past 20 years,and the net accumulation rates are 700 g·cm-2·a-1and 6 g·cm-2·a-1 at sites N30 and N50,respectively.In the eastern part of the Nelson Ice Cap,the accu-mulation rate may be higher than that in the northern part,because no volcanic ash in ice cores was observedat similar depths collected from this region.

  19. Death of Nelson Mandela: CERN and its Staff Association in history

    CERN Document Server

    Staff Association

    2013-01-01

    Shortly after the conviction of Nelson Mandela at the Rivonia trial in 1964, the Anti-Apartheid Movement of Geneva was created at a meeting at CERN. Arriving at CERN as Visiting Scientist in June 1966, I joined the Anti-Apartheid Movement immediately. We multiplied the initiatives at CERN and outside of CERN until the release of Mandela with citizens of Geneva, but also with "citizens of the world", who ignored the ban on political activity, particularly for international civil servants. The Anti-Apartheid Movement of Geneva soon became the Anti-Apartheid Movement of Switzerland. It was also the first Anti-Apartheid Movement outside of South Africa. CERN today is honoured to have brought it to the baptismal font thanks to the initiative of several colleagues, including Mike Pentz, president of the CERN staff Association for two years (1961  1963) and also a refugee from South Africa in Europe. Conclusion: well-targeted disobedience can advance humanity. Jean-Pierre Lagnaux, former vis...

  20. Generalization of Martinelli-Nelson method of pressure drop calculation in two-phase flows

    Directory of Open Access Journals (Sweden)

    Trela Marian

    2017-01-01

    Full Text Available A simple method of pressure drop calculation for two-phase flows of different fluids during convective boiling in channels is presented. It is based on experimental data of pressure drop multiplier R and void fraction φ obtained by Martinelli and Nelson for boiling of water in vertical tubes. The data cover the whole two-phase domain from ambient to critical pressure. Unfortunately, they have been presented in graphical forms. The first step in the procedure proposed in the paper was a transformation of the graphical data into analytical formulas which contain such dimensionless quantities as steam quality x, Martinelli parameter X, multiplier Φl2 and dimensionless coefficients D, m, E and k. In the second step, simple analytical formulas were determined to express the dimensionless coefficients as a function of physical property parameter K. In this way two simple analytical expressions for the multiplier R and void fraction φ were obtained. They are in analytical dimensionless form so they may be used directly for different fluids, not only for water. This is the main advantage of the proposed method.

  1. About Lorentz-M{\\o}ller-Nelson transformation to rigid noninertial frame of reference

    CERN Document Server

    Voytik, Vitaliy V

    2012-01-01

    With a special Lorentz-M{\\o}ller-Nelson (LMN) transformation found transformation of velocity from the laboratory system S to an arbitrary rigid progressively moving reference frame s. Set the physical meaning of the parameter $\\mathbf{v}(t)$ in the appropriate LMN transformation. For small distances, and their proper smooth motion without jerks suggested the reverse special LMN transformation. The main consequences of this transformation is considered, namely, a) the desync in moving frame of reference s of proper clocks of the pre-synchronized in the laboratory frame S and b) the Lorentz contraction of proper rulers frame s in the frame S. The applicability of the reverse LMN transformation for real frames with maximum rigidity is established. Equations for the rotation matrix is obtained. It is shown that the intrinsic rotation of the axes s, considered with respect to S is not rigid. Found the direct and inverse transformation of affine velocity S in the comoving but not rotating frame of s. It is shown t...

  2. Rep-PCR--a variant to RAPD or an independent technique of bacteria genotyping? A comparison of the typing properties of rep-PCR with other recognised methods of genotyping of microorganisms.

    Science.gov (United States)

    Baldy-Chudzik, K

    2001-01-01

    The paper presents technical aspects of rep-PCR fingerprinting technique and compares its typing abilities, differentiation power and reproducibility with other recognised and recommended genotyping methods. Although rep-PCR fingerprinting is similar to MAAP techniques, it demonstrates some essentially different elements. The data presented in this review, indicate a rep-PCR genomic fingerprinting technique as a highly discriminating, independent screening method for determining the taxonomical diversity of bacterial population.

  3. provincia de Buenos Aires (República Argentina

    Directory of Open Access Journals (Sweden)

    Rubén Alberto Cervini

    2008-01-01

    Full Text Available En el estudio que se informa se investigaron las relaciones entre progreso de aprendizaje (valor agregado, motivación y autoconcepto académico del alumno en Matemática, en el marco de los efectos de las características socioeconómicas y académicas del alumno y de su escuela. Para la medición del valor agregado se utilizaron los resultados de dos pruebas estandarizadas de Matemática aplicadas a una cohorte de alumnos de la Provincia de Buenos Aires (República Argentina en dos momentos diferentes (séptimo y noveno años de Educación General Bási ca - EGB. Las mediciones de motivación y de autoconcepto se basaron en respuestas a ítemes binarios de actitudes con respecto a Ma temática y fueron definidas utilizando el análisis de la componente prin - cipal, a partir de la matriz de correlación tetracórica (método heurístico. Para el análisis de las correlaciones se utilizó la téc nica estadística de modelos multinivel. El presente estudio relaciona los resultados empíricos con la teoría del habitus de Bourdieu. Inicialmente, el autoconcepto resulta significativa y positivamente asociado con el puntaje en la prueba y con el progreso de aprendizaje posterior. Este efecto continúa siendo significati vo aun cuando se controlan los efectos del nivel socioeconómi - co y del género del alumno. Sin embargo, su capacidad ex plicativa es muy tenue desde el punto de vista práctico. Si bien este resultado confirmaría la hipótesis central de la teoría de la reproducción, indica un sendero a través del cual podrían producirse transformaciones. Uno de los desafíos del sistema educativo es promover el habitus escolar cultivado (autoconcepto más allá de las determinaciones sociales, culturales y económicas.

  4. rep-PCR-Mediated Genomic Fingerprinting: A Rapid and Effective Method to Identify Clavibacter michiganensis.

    Science.gov (United States)

    Louws, F J; Bell, J; Medina-Mora, C M; Smart, C D; Opgenorth, D; Ishimaru, C A; Hausbeck, M K; de Bruijn, F J; Fulbright, D W

    1998-08-01

    ABSTRACT The genomic DNA fingerprinting technique known as repetitive-sequence-based polymerase chain reaction (rep-PCR) was evaluated as a tool to differentiate subspecies of Clavibacter michiganensis, with special emphasis on C. michiganensis subsp. michiganensis, the pathogen responsible for bacterial canker of tomato. DNA primers (REP, ERIC, and BOX), corresponding to conserved repetitive element motifs in the genomes of diverse bacterial species, were used to generate genomic fingerprints of C. michiganensis subsp. michiganensis, C. michiganensis subsp. sepedonicus, C. michiganensis subsp. nebraskensis, C. michiganensis subsp. tessellarius, and C. michiganensis subsp. insidiosum. The rep-PCR-generated patterns of DNA fragments observed after agarose gel electrophoresis support the current division of C. michiganensis into five subspecies. In addition, the rep-PCR fingerprints identified at least four types (A, B, C, and D) within C. michiganensis subsp. michiganensis based on limited DNA polymorphisms; the ability to differentiate individual strains may be of potential use in studies on the epidemiology and host-pathogen interactions of this organism. In addition, we have recovered from diseased tomato plants a relatively large number of naturally occurring avirulent C. michiganensis subsp. michiganensis strains with rep-PCR fingerprints identical to those of virulent C. michiganensis subsp. michiganensis strains.

  5. The oligomeric Rep protein of Mungbean yellow mosaic India virus (MYMIV) is a likely replicative helicase.

    Science.gov (United States)

    Choudhury, Nirupam Roy; Malik, Punjab Singh; Singh, Dharmendra Kumar; Islam, Mohammad Nurul; Kaliappan, Kosalai; Mukherjee, Sunil Kumar

    2006-01-01

    Geminiviruses replicate by rolling circle mode of replication (RCR) and the viral Rep protein initiates RCR by the site-specific nicking at a conserved nonamer (TAATATT downward arrow AC) sequence. The mechanism of subsequent steps of the replication process, e.g. helicase activity to drive fork-elongation, etc. has largely remained obscure. Here we show that Rep of a geminivirus, namely, Mungbean yellow mosaic India virus (MYMIV), acts as a replicative helicase. The Rep-helicase, requiring > or =6 nt space for its efficient activity, translocates in the 3'-->5' direction, and the presence of forked junction in the substrate does not influence the activity to any great extent. Rep forms a large oligomeric complex and the helicase activity is dependent on the oligomeric conformation ( approximately 24mer). The role of Rep as a replicative helicase has been demonstrated through ex vivo studies in Saccharomyces cerevisiae and in planta analyses in Nicotiana tabacum. We also establish that such helicase activity is not confined to the MYMIV system alone, but is also true with at least two other begomoviruses, viz., Mungbean yellow mosaic virus (MYMV) and Indian cassava mosaic virus (ICMV).

  6. Maximizing collections from patient services billing.

    Science.gov (United States)

    Orenstein, Gil C; Kaye, Alan David; Fox, Charles J; Urman, Richard D

    2014-01-01

    The field of medical billing and collections continues to evolve along with current developments in U.S. healthcare reform. Although there has been a significant shift of payment responsibility from third-party payers to patients, many practices are not equipped to handle this change. As patients' financial obligations increase, the physician's ability to collect from patients will become increasingly important. Inability to collect bills receivable can adversely affect the revenue cycle of the practice. Solutions include improvement of the point-of-service collection processes, properly trained office staff, written financial policies, and the use of technology to facilitate online payments. Patients should fully understand their financial responsibilities and options available to them for payment of services rendered.

  7. Digitalization of incoming mail and incoming bills

    OpenAIRE

    Huč, Andrej

    2012-01-01

    The purpose of this thesis is to provide an overview of the processes involved in the digitalization of materials and having consideration of legal regulations, restrictions and recommendations, make the digitalization process of incoming mail and incoming bills as a cloud-based service. Having an efficient document management system has a significantly positive effect on an organization. In order for documents to be managed more easily and efficiently, they must be converted into an electron...

  8. Geologic map of the Nelson quadrangle, Lewis and Clark County, Montana

    Science.gov (United States)

    Reynolds, Mitchell W.; Hays, William H.

    2003-01-01

    The geologic map of the Nelson quadrangle, scale 1:24,000, was prepared as part of the Montana Investigations Project to provide new information on the stratigraphy, structure, and geologic history of an area in the geologically complex southern part of the Montana disturbed belt. In the Nelson area, rocks ranging in age from Middle Proterozoic through Cretaceous are exposed on three major thrust plates in which rocks have been telescoped eastward. Rocks within the thrust plates are folded and broken by thrust faults of smaller displacement than the major bounding thrust faults. Middle and Late Tertiary sedimentary and volcaniclastic rocks unconformably overlie the pre-Tertiary rocks. A major normal fault displaces rocks of the western half of the quadrangle down on the west with respect to strata of the eastern part. Alluvial and terrace gravels and local landslide deposits are present in valley bottoms and on canyon walls in the deeply dissected terrain. Different stratigraphic successions are exposed at different structural levels across the quadrangle. In the northeastern part, strata of the Middle Cambrian Flathead Sandstone, Wolsey Shale, and Meagher Limestone, the Middle and Upper Cambrian Pilgrim Formation and Park Shale undivided, the Devonian Maywood, Jefferson, and lower part of the Three Forks Formation, and Lower and Upper Mississippian rocks assigned to the upper part of the Three Forks Formation and the overlying Lodgepole and Mission Canyon Limestones are complexly folded and faulted. These deformed strata are overlain structurally in the east-central part of the quadrangle by a succession of strata including the Middle Proterozoic Greyson Formation and the Paleozoic succession from the Flathead Sandstone upward through the Lodgepole Limestone. In the east-central area, the Flathead Sandstone rests unconformably on the middle part of the Greyson Formation. The north edge, northwest quarter, and south half of the quadrangle are underlain by a

  9. Ilmumised ja mediteerimised / Bill Viola ; interv. Harry Liivrand

    Index Scriptorium Estoniae

    Viola, Bill

    1998-01-01

    Bill Viola videoretrospektiiv Stedelijk Museumis, Rijksmuseumis, New Metropolises jm. Amsterdamis 29. novembrini. H. Liivrand Bill Violast ja tema loomingust. B. Viola oma videokunstist praegu ja 25 aastat tagasi, mil tema alustas, mõjutustest loomingule.

  10. Ilmumised ja mediteerimised / Bill Viola ; interv. Harry Liivrand

    Index Scriptorium Estoniae

    Viola, Bill

    1998-01-01

    Bill Viola videoretrospektiiv Stedelijk Museumis, Rijksmuseumis, New Metropolises jm. Amsterdamis 29. novembrini. H. Liivrand Bill Violast ja tema loomingust. B. Viola oma videokunstist praegu ja 25 aastat tagasi, mil tema alustas, mõjutustest loomingule.

  11. Law on Negotiable Bills of Exchange to Be Revised

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    China Banking Regulatory Commission(CBRC) will revise the Law on Negotiable Bills of Exchange cooperating with the relevant government departments. CBRC will discuss with the relevant departments on the specific regulatory work on bank bill and on the system

  12. The Past, Present, and Future of the Bill of Rights.

    Science.gov (United States)

    Pahl, Ronald H.

    1991-01-01

    Examines the origins of the Bill of Rights. Explores the temptation to focus on current problems at the expense of the future. Introduces four articles concerning teaching about the Bill of Rights. (SG)

  13. Radioisotope Electric Propulsion (REP): A Near-Term Approach to Nuclear Propulsion

    Science.gov (United States)

    Schmidt, George R.; Manzella, David H.; Kamhawi, Hani; Kremic, Tibor; Oleson, Steven R.; Dankanich, John W.; Dudzinski, Leonard A.

    2009-01-01

    Studies over the last decade have shown radioisotope-based nuclear electric propulsion to be enhancing and, in some cases, enabling for many potential robotic science missions. Also known as radioisotope electric propulsion (REP), the technology offers the performance advantages of traditional reactor-powered electric propulsion (i.e., high specific impulse propulsion at large distances from the Sun), but with much smaller, affordable spacecraft. Future use of REP requires development of radioisotope power sources with system specific powers well above that of current systems. The US Department of Energy and NASA have developed an advanced Stirling radioisotope generator (ASRG) engineering unit, which was subjected to rigorous flight qualification-level tests in 2008, and began extended lifetime testing later that year. This advancement, along with recent work on small ion thrusters and life extension technology for Hall thrusters, could enable missions using REP sometime during the next decade.

  14. Spreading the Eco-Message: Using Proactive Coping to Aid Eco-Rep Behavior Change Programming

    Directory of Open Access Journals (Sweden)

    Matthew J. Zawadzki

    2013-04-01

    Full Text Available Making pro-environmental behavior changes can be difficult, particularly when these changes challenge daily routines and comfortable lifestyles. We designed and implemented an eco-representative intervention program to help students reduce their energy use by proactively coping with barriers to pro-environmental behavior change, and then communicate effective behavior change strategies to student peers. Twenty-nine first-year college students participated in a four-week proactive coping training to change five environmentally impactful behaviors and then spread behavior change messages to fellow residents during a two-week energy challenge. Eco-reps successfully changed their own behaviors in a pro-environmental direction by generating important barriers and successful facilitators for behavior change, and eco-rep residence halls were more likely to reduce energy and maintain reductions compared to non-eco-rep halls. Implications for future environmental behavior change interventions are discussed.

  15. DIMENSION VARIATION OF FEATURE-BASED MODEL BY OPERATING DIRECTLY ON B-REP

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    A new algorithm for dimension variation of feature-based models is developed.The algorithm is based on B-Rep/CSG hybrid scheme and operates directly on B-Rep.Product information (including the features locating dimensions and other data for manufacture) will not lose after model variation and modification.Furthermore, the definition and solution of features constraints are also supported.The scheme of directly operating on B-Rep overcomes many drawbacks of other proposed methods, most of which need to redo all of the previous work to implement dimension variation, so the computational cost is expensive and product information will lose.What is presented in this paper makes a new way in the area of parametric design.

  16. 42 CFR 408.82 - Conditions for group billing.

    Science.gov (United States)

    2010-10-01

    ... for group billing. CMS agrees to a group billing arrangement only if the following conditions are met... by the State under a buy-in agreement. (c) Protection of enrollee's rights. The use of group billing... maximum feasible protection of the rights specified in paragraph (c) of this section, each enrollee...

  17. 9 CFR 590.130 - Basis of billing plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Basis of billing plants. 590.130... of Service § 590.130 Basis of billing plants. Overtime and/or holiday services shall be billed to the official plant on the basis of each 15 minutes of overtime and/or holiday service performed by...

  18. Validation of the standardized and simplified cutting bill

    Science.gov (United States)

    Urs Buehlmann; D. Earl Kline; Janice K. Wiedenbeck; R., Jr. Noble

    2008-01-01

    This research validated the framework for the standardized and simplified cutting bill presented in an earlier paper. The cutting bill validation was carried out in two ways. First, all 20 of the cutting bill's part groups were examined to determine if significant yield influences resulted from changing specific part sizes within the boundaries of a given part...

  19. Defense Authorization and Appropriations Bills: FY1970-FY2017

    Science.gov (United States)

    2017-01-18

    their numbers and votes, vetoes, substitutions, dates of final passage, and public law numbers. Significant definitions are also included. This...The appropriations bill actually enables the military departments and defense agencies to draw funds from the national treasury. Ideally , the... Ideally , after the authorization bill is passed, the appropriations bill goes through this same process. Although conceptually a sequential process

  20. Defense Authorization and Appropriations Bills: FY1970-FY2016

    Science.gov (United States)

    2016-04-20

    their numbers and votes, vetoes, substitutions, dates of final passage, and public law numbers. Significant definitions are also included. This report...The appropriations bill actually enables the military departments and defense agencies to draw funds from the national treasury. Ideally , the... Ideally , after the authorization bill is passed, the appropriations bill goes through this same process. Although conceptually a sequential process

  1. 77 FR 75355 - Bill of Rights Day, 2012

    Science.gov (United States)

    2012-12-19

    ... December 19, 2012 Part V The President Proclamation 8916--Bill of Rights Day, 2012 Proclamation 8917...; #0; #0;Title 3-- #0;The President ] Proclamation 8916 of December 14, 2012 Bill of Rights Day, 2012... recognized the 150th anniversary of our Nation's Bill of Rights, he called it the ``great American charter of...

  2. 76 FR 77365 - Bill of Rights Day, 2011

    Science.gov (United States)

    2011-12-13

    ... Documents#0;#0; ] Proclamation 8766 of December 8, 2011 Bill of Rights Day, 2011 By the President of the... universal rights and perfecting our Union. Introduced in the First Congress in 1789, the Bill of Rights was... our country's history, generations have risen to uphold the principles outlined in our Bill of Rights...

  3. 78 FR 76719 - Bill of Rights Day, 2013

    Science.gov (United States)

    2013-12-18

    ... Documents#0;#0; ] Proclamation 9070 of December 13, 2013 Bill of Rights Day, 2013 By the President of the... experimentation and national debate, the Bill of Rights came into force, touching off a long journey to carve America's highest ideals into enduring, enforceable law. The Bill of Rights is the foundation of American...

  4. Empirical research of the term structure of intertsts'rate on the Treasury bond market base on the Nelson-Siegel approach.%基于Nelson-Siegel模型的国债收益曲线拟合

    Institute of Scientific and Technical Information of China (English)

    覃聃

    2009-01-01

    本文用Nelson-Siegel方法利用交易所国债数据时我国国债利率期限结构做了静态估计,估计结果显示此方法较好的拟合了我国国债利率期限结构,比较适合我国国债市场.同时拟合结果也反应出我国国债利率期限结构存在的问题.

  5. Recuperar la història de la Segona República Espanyola

    OpenAIRE

    Fontana, Josep, 1931-

    2003-01-01

    L'article recull un discurs de Josep Fontana pronunciat l'octubre de 2002 a la Universitat Autònoma de Barcelona on reflexiona entorn la necessitat de formular una nova lectura història de la Segona República espanyola, de la guerra civil i del franquisme. El artículo recoge un discurso de Josep Fontana pronunciado en octubre del 2002 en la Universitat Autònoma de Barcelona donde reflexiona acerca de la necesidad de formular una nueva lectura de la historia de la Segunda República española...

  6. Design of a Battery Intermediate Storage System for Rep-Rated Pulsed Power Loads

    Science.gov (United States)

    2013-04-01

    Abstract—The U.S. Naval Research Laboratory (NRL) is developing a battery-powered, rep-rate charger for a 60-kJ capacitor bank . The capacitor ...developing a rapid charger for a 60-kJ capacitor bank capable of charging a 4800- µF capacitor to 5-kV in roughly five seconds. This system needs to...U.S. Naval Research Laboratory (NRL) is developing a battery-powered, rep-rate charger for a 60-kJ capacitor bank . The capacitor will be charged with

  7. El derecho del trabajo democrático en la República de Weimar

    OpenAIRE

    Gil Albuerquerque, Román de la Trinidad

    2016-01-01

    La tesis "El Derecho del Trabajo democrático en la República de Weimar" es, de una parte, una introducción contextualizadora a la historia político-social, sindical, del Derecho del Trabajo y de la obra de significados juristas demócratas comprometidos con el nacimiento de la nueva disciplina jurídica (y en parte responsables de su constitucionalización) y con su desarrollo en la República de Weimar, así como una consideración transversal y comparativa de varias instituciones fundamentales p...

  8. El derecho del trabajo democrático en la República de Weimar

    OpenAIRE

    Gil Albuerquerque, Román de la Trinidad

    2016-01-01

    La tesis "El Derecho del Trabajo democrático en la República de Weimar" es, de una parte, una introducción contextualizadora a la historia político-social, sindical, del Derecho del Trabajo y de la obra de significados juristas demócratas comprometidos con el nacimiento de la nueva disciplina jurídica (y en parte responsables de su constitucionalización) y con su desarrollo en la República de Weimar, así como una consideración transversal y comparativa de varias instituciones fundamentales p...

  9. Determination of genetic differences between fluid and nonfluid variants of Clavibacter michiganensis subsp. sepedonicus using rep-PCR technique.

    Science.gov (United States)

    Fousek, J; Mráz, I

    2003-01-01

    Testing of 23 isolates of Clavibacter michiganensis subsp. sepedonicus for analysis by rep-PCR (using BOX, ERIC, REP primer sets) was used for the purpose of localization of genetic markers for fluid and/or nonfluid strains. None of the primer sets was successful in detecting genetic differences between the isolates and no polymorphism was generated.

  10. 75 FR 32493 - NUREG-0654/FEMA-REP-, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-06-08

    ... SECURITY Federal Emergency Management Agency NUREG-0654/FEMA-REP-, Rev. 1, Supplement 3, Guidance for... be held to discuss the proposed Supplement 3 to NUREG-0654/FEMA-REP-1, Rev.1, Guidance for Protective Action Recommendations for General Emergencies (NUREG Supp 3). NUREG Supp 3 addresses onsite and...

  11. Wigner Measures Approach to the Classical Limit of the Nelson Model: Convergence of Dynamics and Ground State Energy

    Science.gov (United States)

    Ammari, Zied; Falconi, Marco

    2014-10-01

    We consider the classical limit of the Nelson model, a system of stable nucleons interacting with a meson field. We prove convergence of the quantum dynamics towards the evolution of the coupled Klein-Gordon-Schrödinger equation. Also, we show that the ground state energy level of nucleons, when is large and the meson field approaches its classical value, is given by the infimum of the classical energy functional at a fixed density of particles. Our study relies on a recently elaborated approach for mean field theory and uses Wigner measures.

  12. Um mundo substituído: jornalismo e jornalistas nas memórias de Nelson Rodrigues

    Directory of Open Access Journals (Sweden)

    Adriano de Paula Rabelo

    2011-08-01

    Full Text Available This article approaches the development of journalism as well as the journalists work in Brazil as they are seen in Nelson Rodrigues memoirs, which were published as a book in 1993, untitled A Menina sem Estrela. In the first part, there is a short division of the history of journalism in periods. Then there comes a discussion of the way this activity is presented in the authors drama. The following part deals with the theory of fiction that support Rodrigues texts. Finally all attention is concentrated on the way journalism and journalists are presented in his memoirs.

  13. Constitutionality of the Plachimada Tribunal Bill, 2011: An Assessment - Comment

    Directory of Open Access Journals (Sweden)

    Sujith Koonan

    2011-09-01

    Full Text Available The Plachimada Coca-Cola Victims Relief and Compensation Claims Special Tribunal Bill, 2011 was passed by the Kerala Legislative Assembly on 24 February 2011. The Bill provides for the establishment of a special tribunal to settle disputes between the local residents and the Hindustan Coca Cola Company in Plachimada for recovery of compensation for damages caused to individuals, property and the environment by the company. The Bill is reserved for the assent of the President of India. In the meantime, the central government has sought clarifications on the Kerala government’s competence under the Constitution to adopt the Bill. The major issue is the perceived inconsistency between the Bill and some of the central environmental laws. Thus, the constitutional validity of the Bill is in doubt. In this background, this paper examines the issue of legislative competence of the Kerala government to adopt the Bill.

  14. Receptors in the bill of the platypus.

    Science.gov (United States)

    Gregory, J E; Iggo, A; McIntyre, A K; Proske, U

    1988-01-01

    1. Afferent responses were recorded from filaments of the trigeminal nerve in each of two platypuses (Ornithorhynchus anatinus) anaesthetized with alpha-chloralose. All receptive fields were located along the lateral border of the upper bill. Discrete receptive fields could be identified as belonging to two distinct classes of sensory receptor. 2. The most prominent response was an irregular resting discharge which could be increased or decreased by weak electric pulses. These receptors were insensitive to moderately strong mechanical stimulation, and it was concluded that they were electroreceptors. 3. Each electroreceptor had a single spot of maximum sensitivity on the bill surface. When the stimulating electrode over this spot was the cathode it excited the receptor for the duration of the stimulating pulse, using stimulus strengths as low as 20 mV. When it was the anode, it inhibited the discharge. Cathodal excitation was followed by rebound inhibition and anodal inhibition by rebound excitation. 4. Receptors responded to cathodal steps with an initial high-frequency burst of impulses, followed by a lower maintained rate of discharge. Rapidly changing pulses were similarly effective in exciting receptors, adding support to the claim that platypuses are able to detect moving prey by the electrical activity associated with muscle contraction. 5. The centres of the receptive fields of two electroreceptors were marked by the insertion of fine entomological pins. Histological examination established the presence of a large mucus-secreting gland at the marked spot. The epidermal duct of the gland contained an elaborate myelinated innervation, with morphologically distinct axon terminals that we identify as the electroreceptors. 6. As well as electroreceptors, the skin of the bill contained three kinds of mechanoreceptors: slow-adapting receptors, rapidly adapting, vibration-sensitive receptors and receptors with an intermediate adaptation rate. The slowly adapting

  15. Electoral (Amendment) (Hours of Polling) Bill 2013

    DEFF Research Database (Denmark)

    Butler, Graham; Hunt, Brian; Doyle, Andrew

    2013-01-01

    Private Members' Bill (legislation) introduced in Dáil Éireann (House of Deputies), Houses of the Oireachtas (Parliament of Ireland). An Act to set voting hours for Dáil Elections, Dáil Bye-Elections, Presidential Elections, European Parliament Elections, Local Government Elections and Referenda...... as being 7.00 a.m. to 10.00 p.m. and for that purpose to amend the Electoral Act 1992, Presidential Elections Act 1993, Referendum Act 1994, European Parliament Elections Act 1997, the Local Government Act 2001 and to provide for related matters....

  16. Equilibrium and kinetics in metamorphism of pelites in the Nelson aureole, British Columbia

    Science.gov (United States)

    Pattison, D. R. M.

    2009-04-01

    The distribution of metapelitic mineral assemblages in the Nelson aureole, British Columbia, generally conforms to what is predicted from phase equilibria. However, in detail, the mineral textures, mineral compositions and zoning, and sequence and spacing of isograds do not. Two of the main disequilibrium features in the aureole are: (1) delay in the onset and progress of several reactions, ie, thermal overstepping; and (2) unreactivity of staurolite and especially garnet porphyroblasts when they are reactants in higher grade reactions. The thermal overstepping is ascribed primarily to difficulty of nucleation of the product porphyroblasts and sluggishness of dissolution of reactant porphyroblasts required for product mineral growth. The extent to which these barriers to nucleation and growth delay the onset of reaction is related to the reaction affinity of each reaction, which for thermally activated reactions is, in turn, related to the entropy change of the reaction. For a given overstep in temperature, reactions that release large quatities of H2O, such as chlorite-consuming reactions, have a high reaction affinity compared to those which release little or no H2O, such as the chlorite-free staurolite-consuming reaction. Thermal overstepping is consequently expected to be less for the former than for the latter, as was observed in the aureole where ca. 30 °C overstepping was required for garnet growth from a muscovite+chlorite-bearing precursor and ca. 70 °C overstepping was required for growth of Al2SiO5 from a staurolite-bearing, chlorite-free precursor. In all cases reaction progress was strongly influenced by presence or absence of fluid, with fluid presence dramatically lowering kinetic barriers to nucleation and growth, and therefore thermal overstepping. Textural features of rocks from the nearly coincident garnet, staurolite and andalusite isograds are suggestive of a fluid-catalyzed ‘cascade effect' in which reaction took place rapidly and several

  17. Global Climate Model Simulated Hydrologic Droughts and Floods in the Nelson-Churchill Watershed

    Science.gov (United States)

    Vieira, M. J. F.; Stadnyk, T. A.; Koenig, K. A.

    2014-12-01

    There is uncertainty surrounding the duration, magnitude and frequency of historical hydroclimatic extremes such as hydrologic droughts and floods prior to the observed record. In regions where paleoclimatic studies are less reliable, Global Climate Models (GCMs) can provide useful information about past hydroclimatic conditions. This study evaluates the use of Coupled Model Intercomparison Project 5 (CMIP5) GCMs to enhance the understanding of historical droughts and floods across the Canadian Prairie region in the Nelson-Churchill Watershed (NCW). The NCW is approximately 1.4 million km2 in size and drains into Hudson Bay in Northern Manitoba, Canada. One hundred years of observed hydrologic records show extended dry and wet periods in this region; however paleoclimatic studies suggest that longer, more severe droughts have occurred in the past. In Manitoba, where hydropower is the primary source of electricity, droughts are of particular interest as they are important for future resource planning. Twenty-three GCMs with daily runoff are evaluated using 16 metrics for skill in reproducing historic annual runoff patterns. A common 56-year historic period of 1950-2005 is used for this evaluation to capture wet and dry periods. GCM runoff is then routed at a grid resolution of 0.25° using the WATFLOOD hydrological model storage-routing algorithm to develop streamflow scenarios. Reservoir operation is naturalized and a consistent temperature scenario is used to determine ice-on and ice-off conditions. These streamflow simulations are compared with the historic record to remove bias using quantile mapping of empirical distribution functions. GCM runoff data from pre-industrial and future projection experiments are also bias corrected to obtain extended streamflow simulations. GCM streamflow simulations of more than 650 years include a stationary (pre-industrial) period and future periods forced by radiative forcing scenarios. Quantile mapping adjusts for magnitude

  18. 中国国债利率期限结构Nelson-Siegel族模型实证比较%Empirical Comparison of term Structure of Interest Rates Based on the Nelson-Siegel Class Models in China

    Institute of Scientific and Technical Information of China (English)

    任姝仪; 杨丰梅; 周荣喜

    2011-01-01

    On the basis of the NS model and SV model,NSM model,FF model and SF model of the Nelson-Siegel class of term structure models of interest rates are summarized,and parameters estimation procedures based on genetic algorithm are given.Finally,the trading data of government bonds in Shanghai Stock Exchange are applied to compare the five models mentioned above.The empirical results show that the fitting accuracy and flexibility of FF model and SF model are superior to the other Nelson-Siegel class models,and that they are suitable for China's bond markets.%在NS模型和SV模型基础上,概述利率期限结构Neson-Siegel族模型中的N SM模型、FF模型及SF模型,并给出基于遗传算法的求解过程,最后应用上海证券交易所的国债数据实证比较了此类参数模型的拟合水平与灵活性。结果表明FF模型与SF模型的拟合精度与灵活性均优于其他模型,能够很好地反映中国国债的利率期限结构。

  19. RiskREP: Risk-Based Security Requirements Elicitation and Prioritization (extended version)

    NARCIS (Netherlands)

    Herrmann, Andrea; Morali, A.

    2010-01-01

    Today, companies are required to be in control of the security of their IT assets. This is especially challenging in the presence of limited budgets and conflicting requirements. Here, we present Risk-Based Requirements Elicitation and Prioritization (RiskREP), a method for managing IT security

  20. Overview of RepLab 2014: Author Profiling and Reputation Dimensions for Online Reputation Management

    NARCIS (Netherlands)

    Amigó, E.; Carrillo-de-Albornoz, J.; Chugur, I.; Corujo, A.; Gonzalo, J.; Meij, E.; de Rijke, M.; Spina, D.

    2014-01-01

    This paper describes the organisation and results of RepLab 2014, the third competitive evaluation campaign for Online Reputation Management systems. This year the focus lied on two new tasks: reputation dimensions classification and author profiling, which complement the aspects of reputation

  1. Romanos e Partos: atividades bélicas na República e no Principado

    OpenAIRE

    Ana Teresa Marques Gonçalves

    2005-01-01

    O objetivo deste artigo é analisar algumas das várias batalhas travadas entre romanos e partos ao longo da República e do Principado, utilizando para tanto as obras de Plutarco, Dion Cássio, Herodiano, Polieno, Eutrópio, Aurélio Victor e Zózimo.

  2. RePS: a sequence assembler that masks exact repeats identified from the shotgun data

    DEFF Research Database (Denmark)

    Wang, Jun; Wong, Gane Ka-Shu; Ni, Peixiang;

    2002-01-01

    We describe a sequence assembler, RePS (repeat-masked Phrap with scaffolding), that explicitly identifies exact 20mer repeats from the shotgun data and removes them prior to the assembly. The established software is used to compute meaningful error probabilities for each base. Clone-end-pairing i...

  3. Simulace dynamiky vozidla využitím software V-REP

    OpenAIRE

    2016-01-01

    Tato práce se zabývá modelováním dynamiky a vizualizací experimentálního vozidla CAR4 v programu V-REP. V první části se práce zabývá představením a možnostmi programu V-REP. V další části je realizováno modelování vozidla CAR4 s následným řízením. K řízení je využit program V-REP a Matlab. V poslední fázi proběhlo testování modelu v simulaci. This theasis deals with modeling dynamics and visualization of experimental vehicle CAR4 in software V-REP. The first part shows introduction with V...

  4. Dictadura, democracia, república: Un análisis conceptual

    OpenAIRE

    Peña, Lorenzo

    2009-01-01

    Conferencia magistral sobre los conceptos de democracia, dictadura y república. "Memoria del Primer Encuentro Internacional sobre el poder en el pasado y el presente de América Latina" coord. por Francisco Lizcano y Guadalupe Zamudio Toluca: Universidad Autónoma del Estado de México, 2009 pp. 29-60. ISBN 978-607-422-069-8.

  5. Bill Barbour : mõned ideed kasvavatele firmadele / Bill Barbour ; interv. Taivo Paju

    Index Scriptorium Estoniae

    Barbour, Bill

    2005-01-01

    Suurbritannia üks kogenumaid ärikonsultante firmade ärikasvumudelist, mis aitab ettevõttel järgmisesse etappi üle minna. Mida peaks ettevõtja enne äri alustamist läbi mõtlema ning millised eesmärgid ja ülesanded enda jaoks paika panema. Lisad: Bill Barbour; Universaalne kriisimudel

  6. Bill Barbour : mõned ideed kasvavatele firmadele / Bill Barbour ; interv. Taivo Paju

    Index Scriptorium Estoniae

    Barbour, Bill

    2005-01-01

    Suurbritannia üks kogenumaid ärikonsultante firmade ärikasvumudelist, mis aitab ettevõttel järgmisesse etappi üle minna. Mida peaks ettevõtja enne äri alustamist läbi mõtlema ning millised eesmärgid ja ülesanded enda jaoks paika panema. Lisad: Bill Barbour; Universaalne kriisimudel

  7. Incentives for HIV testing at the workplace in the automotive industry in the Nelson Mandela Bay Municipality: Ethical considerations

    Directory of Open Access Journals (Sweden)

    Martin Weihs

    2017-07-01

    Full Text Available Comprehensive HIV and AIDS workplace programmes made use of substantial lottery incentives in HIV counselling and testing drives to promote HIV testing at four companies in the automotive industry in the Nelson Mandela Bay Municipality. The main aim was to use lottery incentives to increase uptake for HIV testing. This would help to define company HIV prevalence and ensure timely support, care and treatment of employees. In total, 1 324 employees, making up about 90% of the total staff, were tested for HIV in the four companies during wellness testing days. In order to gain an understanding of employees’ experiences of the lotteries as part of the HIV counselling and testing drive, quantitative data were collected among a total of 414 employees, and 17 interviews were conducted in the four companies. In this article, we investigate the issue of whether the lotteries unduly influenced the employees’ participation in workplace HIV testing, and an approach to resolving an identified ethical dilemma is presented. The ethical question as to whether lottery incentives contribute to undue coercion was explored using both a utilitarian and a deontological approach. The analysis concluded that the use of lotteries to encourage HIV testing in the workplaces of the automotive industry in the Nelson Mandela Bay Municipality can be deemed morally acceptable.

  8. Genetic Diversity and Evidence for Transmission of Streptococcus mutans by DiversiLab rep-PCR.

    Science.gov (United States)

    Momeni, Stephanie S; Whiddon, Jennifer; Cheon, Kyounga; Ghazal, Tariq; Moser, Stephen A; Childers, Noel K

    2016-09-01

    This two-part study investigated the genetic diversity and transmission of Streptococcus mutans using the DiversiLab repetitive extragenic palindromic PCR (rep-PCR) approach. For children with S. mutans and participating household members, analysis for evidence of unrelated child-to-child as well as intra-familial transmission was evaluated based on commonality of genotypes. A total of 169 index children and 425 household family members from Uniontown, Alabama were evaluated for genetic diversity using rep-PCR. Thirty-four unique rep-PCR genotypes were observed for 13,906 S. mutans isolates. For transmission, 117 child and household isolates were evaluated for shared genotype (by child and by genotype cases, multiple matches possible for each child). Overall, children had 1-9 genotypes and those with multiple genotypes were 2.3 times more likely to have caries experience (decayed, missing and filled teeth/surfaces>0). Only 28% of children shared all genotypes within the household, while 72% had at least 1 genotype not shared with anyone in the household. Children had genotype(s) not shared with any household members in 157 cases. In 158 cases children and household members shared a genotype in which 55% (87/158 cases) were shared with more than one family member. Children most frequently shared genotypes with their mothers (54%; 85/158), siblings (46%; 72/158) and cousins (23%; 37/158). A reference library for S. mutans for epidemiological surveillance using the DiversiLab rep-PCR approach is detailed. The genetic diversity of S. mutans in this population demonstrated frequent commonality of genotypes. Evidence for both child-to-child and intra-familial transmission of S. mutans was observed by rep-PCR.

  9. Habitat type and ambient temperature contribute to bill morphology.

    Science.gov (United States)

    Luther, David; Greenberg, Russell

    2014-03-01

    Avian bills are iconic structures for the study of ecology and evolution, with hypotheses about the morphological structure of bills dating back to Darwin. Several ecological and physiological hypotheses have been developed to explain the evolution of the morphology of bill shape. Here, we test some of these hypotheses such as the role of habitat, ambient temperature, body size, intraspecific competition, and ecological release on the evolution of bill morphology. Bill morphology and tarsus length were measured from museum specimens of yellow warblers, and grouped by habitat type, sex, and subspecies. We calculated the mean maximum daily temperature for the month of July, the hottest month for breeding specimens at each collecting location. Analysis of covariance models predicted total bill surface area as a function of sex, habitat type, body size, and temperature, and model selection techniques were used to select the best model. Habitat, mangrove forests compared with inland habitats, and climate had the largest effects on bill size. Coastal wetland habitats and island populations of yellow warblers had similar bill morphology, both of which are larger than mainland inland populations. Temperate but not tropical subspecies exhibited sexual dimorphism in bill morphology. Overall, this study provides evidence that multiple environmental factors, such as temperature and habitat, contribute to the evolution of bill morphology.

  10. On the Reconciliation of the Extended Nelson-Siegel and the Extended Vasicek Models (with a View Towards Swap and Swaption Valuation)

    DEFF Research Database (Denmark)

    Jørgensen, Peter Løchte

    Extended Nelson-Siegel models are widely used by e.g. practitioners and central banks to estimate current term structures of riskless zero-coupon interest rates, whereas other models such as the extended Vasicek model (a.k.a. the Hull-White model) are popular for pricing interest rate derivatives....... This paper establishes theoretical consistency between these two types of models by showing how to specify the extended Vasicek model such that its implied initial term structure curve precisely matches a given extended Nelson-Siegel specification. That is, we show how to reconcile the two classes of models...

  11. Se parece com Nelson é vida ou A Psicanálise como ela é...: narrativas de uma investigação psicanalítica

    OpenAIRE

    Costa, Rafael de Melo

    2013-01-01

    Trata-se de um estudo investigativo que, sob a lente interpretante do método psicanalítico, coloca em questão os conceitos de interpretação psicanalítica e realidade psíquica, a partir de uma analogia estabelecida entre os movimentos de criação na Literatura de Nelson Rodrigues e aqueles oriundos das produções psicanalíticas. A leitura de A vida como ela é..., série de contos escrita por Nelson Rodrigues, para o jornal Última Hora, entre os anos de 1951 e 1961, caracterizou-se ...

  12. 41 CFR 102-117.85 - What is the difference between a Government bill of lading (GBL) and a bill of lading?

    Science.gov (United States)

    2010-07-01

    ... between a Government bill of lading (GBL) and a bill of lading? 102-117.85 Section 102-117.85 Public... Services § 102-117.85 What is the difference between a Government bill of lading (GBL) and a bill of lading? (a) A Government bill of lading (GBL), Optional Forms 1103 and 1203, is a controlled document...

  13. Pre-amyloid oligomers of the proteotoxic RepA-WH1 prionoid assemble at the bacterial nucleoid

    Science.gov (United States)

    Moreno-del Álamo, María; de la Espina, Susana Moreno-Díaz; Fernández-Tresguerres, M. Elena; Giraldo, Rafael

    2015-01-01

    Upon binding to short specific dsDNA sequences in vitro, the N-terminal WH1 domain of the plasmid DNA replication initiator RepA assembles as amyloid fibres. These are bundles of single or double twisted tubular filaments in which distorted RepA-WH1 monomers are the building blocks. When expressed in Escherichia coli, RepA-WH1 triggers the first synthetic amyloid proteinopathy in bacteria, recapitulating some of the features of mammalian prion diseases: it is vertically transmissible, albeit non-infectious, showing up in at least two phenotypically distinct and interconvertible strains. Here we report B3h7, a monoclonal antibody specific for oligomers of RepA-WH1, but which does not recognize the mature amyloid fibres. Unlike a control polyclonal antibody generated against the soluble protein, B3h7 interferes in vitro with DNA-promoted or amyloid-seeded assembly of RepA-WH1 fibres, thus the targeted oligomers are on-pathway amyloidogenic intermediates. Immuno-electron microscopy with B3h7 on thin sections of E. coli cells expressing RepA-WH1 consistently labels the bacterial nucleoid, but not the large cytoplasmic aggregates of the protein. This observation points to the nucleoid as the place where oligomeric amyloid precursors of RepA-WH1 are generated, and suggests that, once nucleated by DNA, further growth must continue in the cytoplasm due to entropic exclusion. PMID:26423724

  14. Practical considerations for conducting effective billing audits.

    Science.gov (United States)

    Bacon, Robert F

    2002-04-01

    Healthcare organizations need to ensure that they are in compliance with government regulations, especially with the increased vigilance by the HHS Office of Inspector General (OIG) in investigating fraud and abuse. After an OIG audit of claims submitted to Medicare by its teaching and resident physicians, the Clinical Practices of the University of Pennsylvania (CPUP), Philadelphia, Pennsylvania, entered into a settlement that included significant financial penalties and a five-year corporate integrity agreement. Lessons learned from the experience may be helpful to other providers in ensuring that their billing practices are in regulatory compliance. As a precautionary measure, providers can undertake their own audits, whether routine or focused. Audits can help providers uncover areas of potential abuse and take steps to correct the problems.

  15. The Maternity Benefit (Amendment Bill, 2016: A Critical Analysis

    Directory of Open Access Journals (Sweden)

    Suman Singh

    2016-11-01

    Full Text Available On 11 August 2016, amending the Maternity Benefit Act, 1961, the new bill, The Maternity Benefit (Amendment Bill, 2016 was introduced and passed in the Rajya Sabha (or Council of States, the upper house of the Parliament of India. Central aim of this article is to critically review the amendments to the bill regarding geographies of maternity leave and its associated facilities.

  16. 78 FR 34250 - Post-9/11 GI Bill

    Science.gov (United States)

    2013-06-07

    ... of the Secretary 32 CFR Part 65 RIN 0790-AI43 Post-9/11 GI Bill AGENCY: Office of the Under Secretary... responsibilities, and prescribes procedures for carrying out the Post-9/11 GI Bill. It establishes policy for the... procedures for carrying out the Post-9/11 GI Bill, as codified in 38 U.S.C. chapter 33. It establishes policy...

  17. A physician's due: measuring physician billing performance, benchmarking results.

    Science.gov (United States)

    Woodcock, Elizabeth W; Browne, Robert C; Jenkins, Jennifer L

    2008-07-01

    A 2008 study focused on four key performance indicators (KPIs) and staffing levels to benchmark the FYO7 performance of physician group billing operations. A comparison of the change in the KPIs from FYO3 to FYO7 for a number of these billing operations disclosed across-the-board improvements. Billing operations did not show significant changes in staffing levels during this time, pointing to the existence of obstacles that prevent staff reductions in this area.

  18. 29 CFR 452.7 - Bill of Rights, title I.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Bill of Rights, title I. 452.7 Section 452.7 Labor... DISCLOSURE ACT OF 1959 Other Provisions of the Act Affecting Title IV § 452.7 Bill of Rights, title I. The provisions of title I, “Bill of Rights of Members of Labor Organizations” 7 (particularly section 101(a)(1...

  19. Draft Surrogacy (Regulation Bill 2016: Rhetoric or Surrogate-centric?

    Directory of Open Access Journals (Sweden)

    Rituparna Bhattacharyya

    2016-11-01

    Full Text Available Chaired by honourable Prime Minister, Mr. Narendra Damodar Modi, the Union Cabinet on 24 August 2016 introduced and approved the draft bill on Assisted Reproductive Technologies (ART in India, known popularly as the Surrogacy (Regulation Bill, 2016. The bill aims at regulating the ever-proliferating unregulated surrogacy industry interalia banning commercial surrogacy services for single parents, homosexuals, cohabiting partners in addition to foreigners and overseas citizens of India. The key aim of this commentary is to make a nuanced examination of the draft bill aimed at gaining a deeper understanding of the practice of surrogacy and address gaps (if any that require interventions.

  20. RepSeq – A database of amino acid repeats present in lower eukaryotic pathogens

    Directory of Open Access Journals (Sweden)

    Smith Deborah F

    2007-04-01

    Full Text Available Abstract Background Amino acid repeat-containing proteins have a broad range of functions and their identification is of relevance to many experimental biologists. In human-infective protozoan parasites (such as the Kinetoplastid and Plasmodium species, they are implicated in immune evasion and have been shown to influence virulence and pathogenicity. RepSeq http://repseq.gugbe.com is a new database of amino acid repeat-containing proteins found in lower eukaryotic pathogens. The RepSeq database is accessed via a web-based application which also provides links to related online tools and databases for further analyses. Results The RepSeq algorithm typically identifies more than 98% of repeat-containing proteins and is capable of identifying both perfect and mismatch repeats. The proportion of proteins that contain repeat elements varies greatly between different families and even species (3–35% of the total protein content. The most common motif type is the Sequence Repeat Region (SRR – a repeated motif containing multiple different amino acid types. Proteins containing Single Amino Acid Repeats (SAARs and Di-Peptide Repeats (DPRs typically account for 0.5–1.0% of the total protein number. Notable exceptions are P. falciparum and D. discoideum, in which 33.67% and 34.28% respectively of the predicted proteomes consist of repeat-containing proteins. These numbers are due to large insertions of low complexity single and multi-codon repeat regions. Conclusion The RepSeq database provides a repository for repeat-containing proteins found in parasitic protozoa. The database allows for both individual and cross-species proteome analyses and also allows users to upload sequences of interest for analysis by the RepSeq algorithm. Identification of repeat-containing proteins provides researchers with a defined subset of proteins which can be analysed by expression profiling and functional characterisation, thereby facilitating study of pathogenicity

  1. ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS

    Directory of Open Access Journals (Sweden)

    Alves-Ferreira Marcelo

    2008-09-01

    Full Text Available Abstract Background Genome survey sequences (GSS offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive regions of the genome. A more precise estimation of the nature, quantity and variability of repetitive sequences very early in a genome sequencing project is of considerable importance, as such data strongly influence the estimation of genome coverage, library quality and progress in scaffold construction. Also, the elimination of repetitive sequences from the initial assembly process is important to avoid errors and unnecessary complexity. Repetitive sequences are also of interest in a variety of other studies, for instance as molecular markers. Results We designed and implemented a straightforward pipeline called ReRep, which combines bioinformatics tools for identifying repetitive structures in a GSS dataset. In a case study, we first applied the pipeline to a set of 970 GSSs, sequenced in our laboratory from the human pathogen Leishmania braziliensis, the causative agent of leishmaniosis, an important public health problem in Brazil. We also verified the applicability of ReRep to new sequencing technologies using a set of 454-reads of an Escheria coli. The behaviour of several parameters in the algorithm is evaluated and suggestions are made for tuning of the analysis. Conclusion The ReRep approach for identification of repetitive elements in GSS datasets proved to be straightforward and efficient. Several potential repetitive sequences were found in a L. braziliensis GSS dataset generated in our laboratory, and further validated by the analysis of a more complete genomic dataset from the EMBL and Sanger Centre databases. ReRep also identified most of the E. coli K12 repeats prior to assembly in an example dataset obtained by automated sequencing using 454 technology. The parameters controlling the algorithm behaved consistently and may be tuned to the properties

  2. 基于Nelson-Siegel模型的我国利率期限结构的构建%Construction of Chinese Term Structure of Interest Rate Based on the Nelson-Siegel Model

    Institute of Scientific and Technical Information of China (English)

    李耀; 赵银

    2014-01-01

    利率问题一直都是经济金融研究中最基础、最核心的问题.利率可以反映出资金的供求状况,并受到物价水平、经济周期和预期等的影响.本文基于中国银行间债券市场的交易数据,利用基于贝叶斯推断的马尔科夫链蒙特卡罗模拟(MCMC)方法估计Hautsch& Ou (2008)提出的动态的Nelson-Siegel模型,以构建我国的利率期限结构模型.

  3. Denudation rates derived from spatially-averaged cosmogenic nuclide analysis in Nelson catchments, South Island, New Zealand

    Science.gov (United States)

    Burdis, A.; Norton, K. P.; Ditchburn, B.; Zondervan, A.

    2013-12-01

    New Zealand's tectonically and climatically dynamic environment generates erosion rates that outstrip global averages by up to ten times in some locations. In order to assess recent changes in erosion rate, and also to predict future erosion dynamics, it is important to quantify long-term, background erosion. Current research on erosion in New Zealand predominantly covers short-term (100 yrs) erosion dynamics and Myr dynamics from thermochronological proxy data. Without medium-term denudation data for New Zealand, it is uncertain which variables (climate, anthropogenic disturbance of the landscape, tectonic uplift, lithological, or geomorphic characteristics) exert the dominant control on denudation in New Zealand. Spatially-averaged cosmogenic nuclide analysis can effectively offer this information by providing averaged rates of denudation on millennial timescales without the biases and limitations of short-term erosion methods. Basin-averaged denudation rates were obtained in the Nelson region, New Zealand, from analysis of concentrations of meteoric 10Be in clay and in-situ produced 10Be in quartz. The measured denudation rates integrate over ~8000 yrs (meteoric) and ~3000 yrs (in-situ). Not only do the 10Be records produce erosion rates that are remarkably consistent with each other, but they are also independent of topographic metrics. Denudation rates range from ~116 - 306 t km-2 yr-1, with the exception of one basin which is eroding at 789 t km-2 yr-1(derived from meteoric 10Be) and 644 t km-2 yr-1(derived from in-situ 10Be). The homogeneity of rates and absence of a significant correlation with geomorphic or lithological characteristics suggest another factor is exerting the dominant control on landscape denudation in the Nelson region. Storm variability is a likely driver of erosion in this setting. The background rates are higher than current short term rates (~50 - 200 t km-2 yr-1) due to the significant erosion caused by high magnitude, low frequency

  4. Detection of lung cancer through low-dose CT screening (NELSON) : a prespecifi ed analysis of screening test performance and interval cancers

    NARCIS (Netherlands)

    Horeweg, Nanda; Scholten, Ernst Th; de Jong, Pim A.; van der Aalst, Carlijn M.; Weenink, Carla; Lammers, Jan-Willem J.; Nackaerts, Kristiaan; Vliegenthart, Rozemarijn; ten Haaf, Kevin; Yousaf-Khan, Uraujh A.; Heuvelmans, Marjolein A.; Thunnissen, Erik; Oudkerk, Matthijs; Mali, Willem; de Koning, Harry J.

    2014-01-01

    Background Low-dose CT screening is recommended for individuals at high risk of developing lung cancer. However, CT screening does not detect all lung cancers: some might be missed at screening, and others can develop in the interval between screens. The NELSON trial is a randomised trial to assess

  5. 77 FR 1667 - Nelson S. Galgoul, Av. Edison Passess 909, Rio De Janeiro, R.J., Brazil 20531-070, Respondent...

    Science.gov (United States)

    2012-01-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Bureau of Industry and Security Nelson S. Galgoul, Av. Edison Passess 909, Rio De Janeiro, R.J., Brazil... a last known address of Av. Edison Passess 909, Rio De Janeiro, R.J., Brazil 20531-070, and when...

  6. Does Deafness Spell Disaster? An Analysis of the Written English Levels of Deaf Children in the Nelson Mandela Metropole, South Africa

    Science.gov (United States)

    Weir, Carolyn; Aylif, Diana

    2014-01-01

    This article presents the findings of an empirical comparative study in the Nelson Mandela Metropole investigating the difference between the written English of deaf children and the written English of hearing children and makes recommendations on how to improve the writing of deaf children. The psycholinguistic approach was used for the…

  7. práctica del turismo rural en la República de Cuba

    Directory of Open Access Journals (Sweden)

    Isis Alejandra Camargo Toribio

    2005-01-01

    Full Text Available El presente trabajo incluye parte de los resultados que se obtuvieron en la tesis doctoral “Aportaciones metodológicas para la implementación del turismo rural en la República de Cuba. Estudio de caso: zona turística de Viñales” (Camargo, 2003. El objetivo principal de este artículo es conocer las preferencias de los clientes internacionales para la práctica del turismo rural, modalidad que no está establecida de forma consciente en la República de Cuba y que, de acuerdo con el potencial naturalcultural existente, tiene amplias posibilidades para su introducción. Con este fin se aplica una encuesta donde los viajeros evalúan, en una escala ascendente, la importancia que le conceden a un conjunto de elementos para la práctica de la modalidad rural

  8. [Stain hybridization method with pRepHind probe for the diagnosis of Plasmodium falciparum].

    Science.gov (United States)

    Moleón Borodowsky, I

    1992-01-01

    A study was conducted on the parasitemia detection level and the specificity of the pRepHind DNA probe for diagnosing Plasmodium falciparum by the stain hybridization method. The parasitemia detection level was studied by using dilutions of a P. falciparum in vitro culture, adjusted by direct microscopic examination to 1; 0.1; 0.01; 0.001; 0.0001 and 0.00001% of parasited red cells. Specificity was increased by using DNA extractions from P. Yoelii, P. berghei and human leucocytes. The results showed that the method was able to detect 0.0001% of parasitemia starting from DNA extractions of 100 L infected red cells. The pRepHind probe only detected specifically DNA from P. falciparum. It is concluded that the method is suitable for being used in the diagnosis of infection due to P. falciparum.

  9. A república e o sonho The republic and its dream

    Directory of Open Access Journals (Sweden)

    Maria Tereza Chaves de Mello

    2011-06-01

    Full Text Available O desencanto com a República brasileira tem sido tema de reflexões desde os seus momentos iniciais. Buscando os conteúdos concretos dos sonhos republicanos na década de 1880 e na Primeira República vamos achar uma importante defasagem entre eles não exatamente em função do marco cronológico, mas do grupo social que, respectivamente, os acalentou.The disillusion with the Brazilian Republic since its first days has been a topic of academician reflexions. Examinating the concrete contents of the 1880`s and the First Republic republican dreams we will find a substantive difference between them. To be exact, this difference must not be related to the chronological demarcation but to the social group that embraced each of them.

  10. A comparative analysis of simulated and observed landslide locations triggered by Hurricane Camille in Nelson County, Virginia

    Science.gov (United States)

    Morrissey, M.M.; Wieczorek, G.F.; Morgan, B.A.

    2008-01-01

    In 1969, Nelson County, Virginia received up to 71 cm of rain within 12 h starting at 7 p.m. on August 19. The total rainfall from the storm exceeded the 1000-year return period in the region. Several thousands of landslides were induced by rainfall associated with Hurricane Camille causing fatalities and destroying infrastructure. We apply a distributed transient response model for regional slope stability analysis to shallow landslides. Initiation points of over 3000 debris flows and effects of flooding from this storm are applied to the model. Geotechnical data used in the calculations are published data from samples of colluvium. Results from these calculations are compared with field observations such as landslide trigger location and timing of debris flows to assess how well the model predicts the spatial and temporal distribution. of landslide initiation locations. The model predicts many of the initiation locations in areas where debris flows are observed. Copyright ?? 2007 John Wiley & Sons, Ltd.

  11. Measuring water accumulation rates using GRACE data in areas experiencing glacial isostatic adjustment: The Nelson River basin

    Science.gov (United States)

    Lambert, A.; Huang, J.; Kamp, G.; Henton, J.; Mazzotti, S.; James, T. S.; Courtier, N.; Barr, A. G.

    2013-12-01

    Recovery and Climate Experiment (GRACE) satellite-derived total water storage can be obscured by glacial isostatic adjustment. In order to solve this problem for the Nelson River drainage basin in Canada, a gravity rate map from 110 months (June 2002 to October 2011) of GRACE gravity data was corrected for glacial isostatic adjustment using an independent gravity rate map derived from updated GPS vertical velocities. The GPS-based map was converted to equivalent gravity rate using a transfer function developed from GPS and absolute-g data at colocated sites. The corrected GRACE gravity rate map revealed a major positive anomaly within the drainage basin, which was independently shown by hydrological data to be due to changes in water storage. The anomaly represents a cumulative increase at its center of about 340 mm of water, reflecting a progression from extreme drought to extremely wet conditions.

  12. 禅之韵——详解Nelson Pass设计的禅(Zen)系列功效

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    译者的话:在《电子制作》第6期专题,给大家介绍了尼尔森·帕斯(Nelson Pass.以下简称:Pass)早期的几个作品。包括对商业GI2功放的改造,Pass自家的产品B1前级,还有从宏观上分析了Pass对音响电源的一些独特观点。许多读者反馈希望能更多的介绍一下Pass的代表做。

  13. Modos de gozo na dor de existir: um estudo psicanalítico sobre A falecida de Nelson Rodrigues

    OpenAIRE

    Ratti, Fabiana Carvalho

    2014-01-01

    Esse trabalho partiu de interrogações clínicas. Porém, ao invés de nos fixarmos num caso clínico, escolhemos um recorte da cultura, uma peça, A Falecida de Nelson Rodrigues, para desenvolver o tema proposto: os modos de gozo na dor de existir. Dessa forma, mantemos o sigilo ético do consultório e utilizamos um recurso contemporâneo à psicanálise como forma de articular as teorias psicanalíticas de Sigmund Freud (1856-1939) e Jacques Lacan (1901-1981). Iniciamos com uma contextualização histór...

  14. Tratamiento tributario actual del comercio electrónico en la República Argentina

    OpenAIRE

    Martínez Giribone, María Silvana

    2010-01-01

    Tratamiento tributario actual del comercio electrónico en la República Argentina. PROBLEMA: ¿Constituye la legislación tributaria argentina aplicada a operaciones comerciales tradicionales un marco legal acorde para gravar operaciones de comercio electrónico? OBJETIVOS DE LA INVESTIGACION OBJETIVO GENERAL Analizar la aplicación de la legislación tributaria argentina para operaciones de comercio tradicionales en el comercio electrónico. OBJETIVOS ESPECIFICOS Ana...

  15. Vanguardismo y problemática del film alemán de la República de Weimar

    OpenAIRE

    Sánchez-Biosca, Vicente

    1985-01-01

    El presente artículo trata de examinar las aproximaciones historiográficas realizadas al cine producido en la República de Weimar, desde el llamado expresionismo hasta las corrientes realistas, pasando por el Kammerspielfilm.

  16. A Comparison of Molecular Typing Methods Applied to Enterobacter cloacae complex: hsp60 Sequencing, Rep-PCR, and MLST

    Directory of Open Access Journals (Sweden)

    Roberto Viau

    2017-02-01

    Full Text Available Molecular typing using repetitive sequenced-based PCR (rep-PCR and hsp60 sequencing were applied to a collection of diverse Enterobacter cloacae complex isolates. To determine the most practical method for reference laboratories, we analyzed 71 E. cloacae complex isolates from sporadic and outbreak occurrences originating from 4 geographic areas. While rep-PCR was more discriminating, hsp60 sequencing provided a broader and a more objective geographical tracking method similar to multilocus sequence typing (MLST. In addition, we suggest that MLST may have higher discriminative power compared to hsp60 sequencing, although rep-PCR remains the most discriminative method for local outbreak investigations. In addition, rep-PCR can be an effective and inexpensive method for local outbreak investigation.

  17. Reps võib kõrvale heita kümme miljonit maksnud õppekava / Dagne Hanschmidt

    Index Scriptorium Estoniae

    Hanschmidt, Dagne

    2005-01-01

    TÜ õppekavade arenduskeskus ja AS Bit koostavad mõlemad riikliku õppekava, lähtudes erinevatest põhimõttest. Haridus- ja teadusminister Mailis Reps ei ole avaldanud, kumba õppekava varianti ta eelistab

  18. Nelson Mandela’s ‘Ordinary Love’ Addressed in Pop-rock Music: a Long Song of Freedom

    Directory of Open Access Journals (Sweden)

    Simona Martini

    2014-11-01

    Full Text Available This paper aims to highlight how inspirational the figure of Nelson Mandela has been for several musicians and songwriters. In particular, it focuses on songs written by Western musicians from the early Eighties until 2013 – all showing the extent to which the South African leader has epitomized the struggle for equality and freedom. This study points out how the success of a hit single in 1984 – British ska group The Special AKA’s “Free Nelson Mandela” – paved the way for a quick increase in the number of musicians who got involved in the anti-apartheid movement and contributed to make Western audiences know about Mandela and increasingly demand that apartheid be put to an end. This survey seeks to examine the main achievements in pop-rock songs that generated both from the growing awareness about the South African leader’s experience when he was imprisoned, and the legacy of his exemplum after he was set free. Among the songs cited: Simple Minds’ “Mandela Day”, the various artists’ tribute “46664” and the most recent Golden Globe-awarded “Ordinary Love” by U2, written for the soundtrack of the biopic The Long Walk to Freedom. To better understand how the figure of Mandela has been addressed in these works, the paper includes analyses of the most complex and significant lyrics among the songs discussed, thus also showing how the South African cultural background as it was received by the West could have informed the songwriting, and how the Western reception of such songs determined an increasing awareness about Mandela’s plight and the whole phenomenon of apartheid.

  19. RepPop: a database for repetitive elements in Populus trichocarpa

    Directory of Open Access Journals (Sweden)

    Xu Ying

    2009-01-01

    Full Text Available Abstract Background Populus trichocarpa is the first tree genome to be completed, and its whole genome is currently being assembled. No functional annotation about the repetitive elements in the Populus trichocarpa genome is currently available. Results We predicted 9,623 repetitive elements in the Populus trichocarpa genome, and assigned functions to 3,075 of them (31.95%. The 9,623 repetitive elements cover ~40% of the current (partially assembled genome. Among the 9,623 repetitive elements, 668 have copies only in the contigs that have not been assigned to one of the 19 chromosome while the rest all have copies in the partially assembled chromosomes. Conclusion All the predicted data are organized into an easy-to-use web-browsable database, RepPop. Various search capabilities are provided against the RepPop database. A Wiki system has been set up to facilitate functional annotation and curation of the repetitive elements by a community rather than just the database developer. The database RepPop will facilitate the assembling and functional characterization of the Populus trichocarpa genome.

  20. RepARK--de novo creation of repeat libraries from whole-genome NGS reads.

    Science.gov (United States)

    Koch, Philipp; Platzer, Matthias; Downie, Bryan R

    2014-05-01

    Generation of repeat libraries is a critical step for analysis of complex genomes. In the era of next-generation sequencing (NGS), such libraries are usually produced using a whole-genome shotgun (WGS) derived reference sequence whose completeness greatly influences the quality of derived repeat libraries. We describe here a de novo repeat assembly method--RepARK (Repetitive motif detection by Assembly of Repetitive K-mers)--which avoids potential biases by using abundant k-mers of NGS WGS reads without requiring a reference genome. For validation, repeat consensuses derived from simulated and real Drosophila melanogaster NGS WGS reads were compared to repeat libraries generated by four established methods. RepARK is orders of magnitude faster than the other methods and generates libraries that are: (i) composed almost entirely of repetitive motifs, (ii) more comprehensive and (iii) almost completely annotated by TEclass. Additionally, we show that the RepARK method is applicable to complex genomes like human and can even serve as a diagnostic tool to identify repetitive sequences contaminating NGS datasets.

  1. A method mediated AAVS1 recombination with Rep mRNA and homologous arms

    Institute of Scientific and Technical Information of China (English)

    Qiantong Xiang; Linian Huang; Sijia Guo; Fang Chen; Xiaojun Zha; Bing Chen; Liangdan Sun; Haisheng Zhou; Depei Liu

    2012-01-01

    The adeno-associated virus (AAV) genome can be stably integrated into the AAVS1 region of human chromosome 19 (19q13.4-qter) with the assistance of Rep68/78 protein.In the current models of AAV integration in a locusspecific manner,the foreign genes were randomly inserted into the AAVS1 region,which contains several functional genes.As random integration in this region may lead to insertion mutations and disrupt normal gene expression or critical signaling pathways of the host cells,it is necessary to find a precise insertion site in the AAVS1 region.Homologous recombination is the most accurate and versatile mechanism for such site-specific integration.To investigate site-specific integration in the AAVS1 region,a targeted vector containing two homologous arms derived from AAVS1 and a reporter gene was transfected into HeLa cells with or without Rep68/78 mRNA.The results indicated that transient expression of Rep68/78 in HeLa cells improved integration of the gene of interest at the AAVS1 locus in a site-specific manner.Compared with locus-specific integration reported in previous studies,sitespecific integration may minimize the risk associated with random DNA integration in the AAVS1 region,which might be helpful for gene therapy.

  2. Design and Implementation of Reconfigurable Embedded Processor (REP for AUV using FPGA

    Directory of Open Access Journals (Sweden)

    Mohd. Rizal Arshad

    2012-09-01

    Full Text Available The superscalar pipeline is something that the REP architecture resembles. The features that are similar in both architectures include rename, decode, fetch as well as in-order front-ends parts as substituted by dispatch units. The physical register file, execute unit, dynamic scheduler and task queue are contained by the out of-order execution core. The architecture also contains the REP that beholds an integrated system of shared-memory. A number of experiments with realistic benchmarks and an FPGA environment are used to synthesize design. The experiments conducted yielded in results that prove that the new architecture of the REP leads to higher performance of applications because of decreased processing time. And the core reason for the deduction of processing time is the simplified complexity of the frequency and area of the architecture. The results show that the least error tolerance is 1m by particle filter. Also, the optimum iteration level is 20 to get enhanceable navigation data for AUV.

  3. Realizace 3D tiskárny typu RepRap

    OpenAIRE

    Sochor, Marek

    2015-01-01

    Cílem bakalářské práce bude sestavení a ověření funkčnosti 3D tiskárny typu RepRap. Tiskárna bude sestavena z běžně dostupných dílů a pro zachování myšlenky RepRap také z dílů tisknutých. Po ověření funkčnosti 3D tiskárny bude vytisknuta identická součást na dvou typech tiskáren (3D tiskárna typu RepRap vs. profesionální tiskárna uPrint) za účelem zhodnocení a celkové analýzy, jak po stránce finanční, tak po stránce fyzické. Práce bude ukončena zhodnocením použitelnosti a konkurenceschopnosti...

  4. China : Development of National Heat Pricing and Billing Policy

    OpenAIRE

    Meyer, Anke Sofia; Kalkum, Bernd

    2008-01-01

    Market-based reforms in China's urban centralized heating sector are essential to addressing the perpetual inefficiency of a sector built on welfare based principles. The reform of heat pricing and billing is a crucial part of overall heat reform, since it will commodity heat and thus create economic incentives to provide and use heat much more efficiently. Heat pricing and billing reform ...

  5. 42 CFR 71.11 - Bills of health.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Bills of health. 71.11 Section 71.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES QUARANTINE, INSPECTION, LICENSING FOREIGN QUARANTINE Measures at Foreign Ports § 71.11 Bills of health. A carrier at any foreign port clearing or...

  6. 19 CFR 142.14 - Delinquent payment of Customs bills.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Delinquent payment of Customs bills. 142.14 Section 142.14 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY... of Customs bills. The following procedure shall be followed if an importer is substantially...

  7. 19 CFR 142.26 - Delinquent payment of Customs bills.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Delinquent payment of Customs bills. 142.26 Section 142.26 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY... Delinquent payment of Customs bills. The following procedures shall be followed if an importer...

  8. 49 CFR 377.205 - Presentation of freight bills.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Presentation of freight bills. 377.205 Section 377.205 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... Household Goods Freight Forwarders § 377.205 Presentation of freight bills. (a) “To be prepaid”...

  9. An Investigation of Telecom Mobile Data Billing Plans

    Directory of Open Access Journals (Sweden)

    Yi-Bing Lin

    2016-08-01

    Full Text Available In the recent years, mobile operators have provided many billing alternatives such as limited and unlimited billing plans, and shared and non-shared data plans for the users with different needs. A non-shared data plan is designed for a single user with a limited monthly data allowance. On the other hand, the monthly data allowance of a shared data plan is shared by a group of users with multiple devices. The mobile operators often conduct the primary price study to compare their billing plans, which shows the relationship between the prices of the billing plans against the fixed amounts of data usage. Although the primary price study can easily and quickly draw the conclusions, it only provides rough billing plan suggestions. In reality, the amounts of data usage are not fixed, and therefore should be measured from commercial mobile networks to reflect the user behaviors on data usage. This paper proposes an analytical approach by using the measured data of Chunghwa Telecom Co., Ltd. (CHT, the largest telecommunications company in Taiwan, to derive the expected payments of various billing plans. The results of the analytical model are more accurate than those of the primary price study, and therefore provide better suggestions for billing plan selection. Other mobile operators can easily use our model to analyze the billing alternatives with their measured data.

  10. 38 CFR 17.1008 - Balance billing prohibited.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Balance billing prohibited. 17.1008 Section 17.1008 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Facilities § 17.1008 Balance billing prohibited. Payment by VA under 38 U.S.C. 1725 on behalf of a veteran...

  11. How sailfish use their bills to capture schooling prey

    DEFF Research Database (Denmark)

    Domenici, P.; Wilson, A.D.M.; Kurvers, R.H.J.M.

    2014-01-01

    on prey. Here, we present the first unequivocal evidence of how the bill is used by Atlantic sailfish (Istiophorus albicans) to attack schooling sardines in the open ocean. Using high-speed video-analysis, we show that (i) sailfish manage to insert their bill into sardine schools without eliciting...

  12. Human-Centered Design Bill of Rights for Educators.

    Science.gov (United States)

    Sugar, William A.

    This paper presents a potential solution to encourage technology adoption and integration within schools by proposing a human-centered technology "bill of rights" for educators. The intention of this bill of rights it to influence educators' beliefs towards technology and to enable educators to confront with confidence the seemingly…

  13. 29 CFR 1205.2 - Employees' Bill of Rights.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Employees' Bill of Rights. 1205.2 Section 1205.2 Labor... Employees' Bill of Rights. The provisions of the third, fourth, and fifth paragraphs of section 2 are by law... provisions the employees are guaranteed the right to organize without interference of management, the right...

  14. Advance Billing and Metering Architecture for Infrastructure as a Service

    Directory of Open Access Journals (Sweden)

    Sukhpal Singh

    2013-01-01

    Full Text Available Billing in Infrastructure as a Service (IaaS is a complex task that is often compromised due to lack of various interactions (Consumer, Provider, Budget Manager, Agent and Online Payment simultaneously along with necessary features like discount, tax, plan etc. Until Billing is considered as a last essential ability, appropriate framework cannot be provided to IaaS cloud consumers. In this paper, IaaS Online Billing System (IOBS has been proposed that describes transparency of consumption, billing and frequency of usage of services for a cloud based pay per use system. This system describes various interactions of network and user interface. The billing rules have been stored in a database. The model has been verified through UML that demonstrates that IOBS is effective in improving user interaction by reducing time and increasing customer satisfaction.

  15. Modulation of pPS10 Host Range by Plasmid-Encoded RepA Initiator Protein

    Science.gov (United States)

    Maestro, Beatriz; Sanz, Jesús M.; Díaz-Orejas, Ramón; Fernández-Tresguerres, Elena

    2003-01-01

    We report here the isolation and analysis of novel repA host range mutants of pPS10, a plasmid originally found in Pseudomonas savastanoi. Upon hydroxylamine treatment, five plasmid mutants were selected for their establishment in Escherichia coli at 37°C, a temperature at which the wild-type form cannot be established. The mutations were located in different functional regions of the plasmid RepA initiation protein, and the mutants differ in their stable maintenance, copy number, and ability to interact with sequences of the basic replicon. Four of them have broadened their host range, and one of them, unable to replicate in Pseudomonas, has therefore changed its host range. Moreover, the mutants also have increased their replication efficiency in strains other than E. coli such as Pseudomonas putida and Alcaligenes faecalis. None of these mutations drastically changed the structure or thermal stability of the wild-type RepA protein, but in all cases an enhanced interaction with host-encoded DnaA protein was detected by gel filtration chromatography. The effects of the mutations on the functionality of RepA protein are discussed in the framework of a three-dimensional model of the protein. We propose possible explanations for the host range effect of the different repA mutants, including the enhancement of limiting interactions of RepA with specific host replication factors such as DnaA. PMID:12562807

  16. Translation initiation of the replication initiator repB gene of promiscuous plasmid pMV158 is led by an extended non-SD sequence.

    Science.gov (United States)

    López-Aguilar, Celeste; Ruiz-Masó, José A; Rubio-Lepe, Tania Samir; Sanz, Marta; del Solar, Gloria

    2013-07-01

    RepB is the pMV158-encoded protein that initiates rolling-circle replication of this promiscuous plasmid. Availability of RepB is rate-limiting for the plasmid replication process, and therefore the repB gene encoding the protein is subjected to strict control. Two trans-acting plasmid elements, CopG and the antisense RNAII, are involved in controlling the synthesis of the initiator at the transcriptional and translational level, respectively. In addition to this dual control of repB expression that senses and corrects fluctuations in plasmid copy number, proper availability of RepB also relies on the adequate functionality of the transcription and translation initiation regulatory signals. Translation of repB has been postulated to depend on an atypical ribosome binding site that precedes its start codon, although such a hypothesis has never been proved. To define sequences involved in translation of repB, several mutations in the translation initiation region of the repB mRNA have been characterized by using an Escherichia coli in vitro expression system wherein the synthesis of RepB was detected and quantified. We showed that translation of repB is not coupled to that of copG and depends only on its own initiation signals. The atypical ribosome binding site, as it was defined, is not involved in translation initiation. However, the sequence just upstream of the repB start codon, encompassing the proximal box of the atypical ribosome binding site and the four bases immediately downstream of it, is indeed important for efficient translation of repB. The high degree of conservation of this sequence among the rep genes of plasmids of the same pMV158 family supports its relevancy as a translation initiation signal in mRNAs without a recognizable Shine-Dalgarno sequence.

  17. 77 FR 20747 - Proposed Amendment of Class E Airspace; Billings, MT

    Science.gov (United States)

    2012-04-06

    ... action proposes to modify Class E airspace at Billings Logan International Airport, Billings, MT, to... feet or more above the surface of the earth. * * * * * ANM MT E5 Billings, MT Billings Logan... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class E Airspace; Billings, MT AGENCY...

  18. A Bill of Rights for Hospitalized Older Adults.

    Science.gov (United States)

    Mezey, Mathy D; Mitty, Ethel

    2011-03-01

    Acute-care hospitals have few structures, programs, or staff prepared to address the special needs of older adults. To address this issue, the Hartford Institute for Geriatric Nursing [including the Nurses Improving Care for Hospitalized Elders (NICHE) program] and the Coalition of Geriatric Nursing Organizations proposed language for a Bill of Rights for Hospitalized Older Adults. The Bill of Rights moves from general value statements to the specific knowledge, skills, and actions necessary to provide quality of care to older adults. The authors describe the development and testing of the Bill of Rights and suggest steps for its adoption and dissemination.

  19. Impact of capsid conformation and Rep-capsid interactions on adeno-associated virus type 2 genome packaging.

    Science.gov (United States)

    Bleker, Svenja; Pawlita, Michael; Kleinschmidt, Jürgen A

    2006-01-01

    Single-stranded genomes of adeno-associated virus (AAV) are packaged into preformed capsids. It has been proposed that packaging is initiated by interaction of genome-bound Rep proteins to the capsid, thereby targeting the genome to the portal of encapsidation. Here we describe a panel of mutants with amino acid exchanges in the pores at the fivefold axes of symmetry on AAV2 capsids with reduced packaging and reduced Rep-capsid interaction. Mutation of two threonines at the rim of the fivefold pore nearly completely abolished Rep-capsid interaction and packaging. This suggests a Rep-binding site at the highly conserved amino acids at or close to the pores formed by the capsid protein pentamers. A different mutant (P. Wu, W. Xiao, T. Conlon, J. Hughes, M. Agbandje-McKenna, T. Ferkol, T. Flotte, and N. Muzyczka, J. Virol. 74:8635-8647, 2000) with an amino acid exchange at the interface of capsid protein pentamers led to a complete block of DNA encapsidation. Analysis of the capsid conformation of this mutant revealed that the pores at the fivefold axes were occupied by VP1/VP2 N termini, thereby preventing DNA introduction into the capsid. Nevertheless, the corresponding capsids had more Rep proteins bound than wild-type AAV, showing that correct Rep interaction with the capsid depends on a defined capsid conformation. Both mutant types together support the conclusion that the pores at the fivefold symmetry axes are involved in genome packaging and that capsid conformation-dependent Rep-capsid interactions play an essential role in the packaging process.

  20. Final screening round of the NELSON lung cancer screening trial: the effect of a 2.5-year screening interval.

    Science.gov (United States)

    Yousaf-Khan, Uraujh; van der Aalst, Carlijn; de Jong, Pim A; Heuvelmans, Marjolein; Scholten, Ernst; Lammers, Jan-Willem; van Ooijen, Peter; Nackaerts, Kristiaan; Weenink, Carla; Groen, Harry; Vliegenthart, Rozemarijn; Ten Haaf, Kevin; Oudkerk, Matthijs; de Koning, Harry

    2017-01-01

    In the USA annual lung cancer screening is recommended. However, the optimal screening strategy (eg, screening interval, screening rounds) is unknown. This study provides results of the fourth screening round after a 2.5-year interval in the Dutch-Belgian Lung Cancer Screening trial (NELSON). Europe's largest, sufficiently powered randomised lung cancer screening trial was designed to determine whether low-dose CT screening reduces lung cancer mortality by ≥25% compared with no screening after 10 years of follow-up. The screening arm (n=7915) received screening at baseline, after 1 year, 2 years and 2.5 years. Performance of the NELSON screening strategy in the final fourth round was evaluated. Comparisons were made between lung cancers detected in the first three rounds, in the final round and during the 2.5-year interval. In round 4, 46 cancers were screen-detected and there were 28 interval cancers between the third and fourth screenings. Compared with the second round screening (1-year interval), in round 4 a higher proportion of stage IIIb/IV cancers (17.3% vs 6.8%, p=0.02) and higher proportions of squamous-cell, bronchoalveolar and small-cell carcinomas (p=0.001) were detected. Compared with a 2-year interval, the 2.5-year interval showed a higher non-significant stage distribution (stage IIIb/IV 17.3% vs 5.2%, p=0.10). Additionally, more interval cancers manifested in the 2.5-year interval than in the intervals of previous rounds (28 vs 5 and 28 vs 19). A 2.5-year interval reduced the effect of screening: the interval cancer rate was higher compared with the 1-year and 2-year intervals, and proportion of advanced disease stage in the final round was higher compared with the previous rounds. ISRCTN63545820. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  1. Transcriptomics of tomato plants infected with TYLCSV or expressing the central TYLCSV Rep protein domain uncover changes impacting pathogen response and senescence.

    Science.gov (United States)

    Lucioli, Alessandra; Perla, Carlo; Berardi, Alessandra; Gatti, Francesca; Spanò, Laura; Tavazza, Mario

    2016-06-01

    To establish a successful infection viruses need to overcome plant innate immune responses and redirect host gene expression for their multiplication and diffusion. Tomato yellow leaf curl Sardinia virus (TYLCSV) is a geminivirus, which causes significant economic losses in tomato. The multifunctional replication associated geminivirus protein (Rep) has an important role during viral infection. In particular, the Rep central domain spanning from aa 120 to 180 is known to interact with viral and host factors. In this study, we used long serial analysis of gene expression to analyse the transcriptional profiles of transgenic tomato plants expressing the first 210 amino acids of TYLCSV Rep (Rep210) and TYLCSV-infected wild-type tomato plants (Wt-Ty). Also, we compared these profiles with those of transgenic Rep130 tomatoes. Comparison of Wt-Ty and Rep210 libraries with the wild-type one identified 118 and 203 differentially expressed genes (DEGs), respectively. Importantly, 55% of Wt-Ty DEGs were in common with Rep210, and no ones showed opposite expression. Conversely, a negligible overlap was found between Rep130 DEGs and Wt-Ty and Rep210 ones. TYLCSV- and Rep210-repressed genes, but not induced ones, overlapped with the leaf senescence process. Interestingly, TYLCSV upregulates expression of genes involved in the negative regulation of programmed cell death (PCD), several of which were also regulated by the abscisic acid. Rep210 upregulated genes related to defence response, immune system processes and negative regulation of PCD. Collectively, our results support a model in which the Rep central domain has a pivotal role in redirecting host plant gene expression.

  2. 47 CFR 76.985 - Subscriber bill itemization.

    Science.gov (United States)

    2010-10-01

    ...) The amount of the total bill assessed as a franchise fee and the identity of the franchising authority... imposed on the cable operator by the franchise agreement to support public, educational, or...

  3. Plümtoonia Bill - nagu orkester / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2008-01-01

    19.-23. nov. toimuvast animafilmide festivalist "Animated Dreams". Pikemalt USA tuntuimast sõltumatust animaatorist Bill Plymtonist, kes näitab festivalil oma täispikka joonisfilmi "Idioodid ja inglid" ("Idiots and Angels")

  4. Soul / Randy Becker, Bill Evans, Evelin Samuel ; interv. Sven Sapelson

    Index Scriptorium Estoniae

    Becker, Randy

    2007-01-01

    The Soulbop Bandi rajajad Randy Becker ja Bill Evans ning meie Evelin Samuel gospeli ja rhytmblues'i juurtega soulist. Lk. 72-73 Inessa Josingu ja Ande Kaalepi souliteemaline fotolavastusega ruumikujundus

  5. Soul / Randy Becker, Bill Evans, Evelin Samuel ; interv. Sven Sapelson

    Index Scriptorium Estoniae

    Becker, Randy

    2007-01-01

    The Soulbop Bandi rajajad Randy Becker ja Bill Evans ning meie Evelin Samuel gospeli ja rhytmblues'i juurtega soulist. Lk. 72-73 Inessa Josingu ja Ande Kaalepi souliteemaline fotolavastusega ruumikujundus

  6. Plümtoonia Bill - nagu orkester / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2008-01-01

    19.-23. nov. toimuvast animafilmide festivalist "Animated Dreams". Pikemalt USA tuntuimast sõltumatust animaatorist Bill Plymtonist, kes näitab festivalil oma täispikka joonisfilmi "Idioodid ja inglid" ("Idiots and Angels")

  7. Statement on Bills to Designate Crab Orchard Wilderness

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Statement of John Kyl on H.R. 3508 and H.R. 5893, bills to designate Crab Orchard Wilderness within Crab Orchard National Wildlife Refuge. This document includes maps.

  8. 47 CFR 76.1619 - Information on subscriber bills.

    Science.gov (United States)

    2010-10-01

    ... credits. (b) In case of a billing dispute, the cable operator must respond to a written complaint from a subscriber within 30 days. (c) A cable franchise authority may enforce the customer service standards...

  9. The Honorable William Nelson, Senior Senator from Florida, Chairman, Senate Committee on Space, Aeronautics and Related Sciences signing the golden book. Greeting by Mr Robert Aymar, CERN Director General and Prof. Samuel Ting from the MIT.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    The Honorable William Nelson, Senior Senator from Florida, Chairman, Senate Committee on Space, Aeronautics and Related Sciences signing the golden book. Greeting by Mr Robert Aymar, CERN Director General and Prof. Samuel Ting from the MIT.

  10. The Honorable William Nelson, Senior Senator from Florida, Chairman, Senate Committee on Space, Aeronautics and Related Sciences visiting the AMS Hall of Prevessin with Prof. Samuel Ting from the MIT.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    The Honorable William Nelson, Senior Senator from Florida, Chairman, Senate Committee on Space, Aeronautics and Related Sciences visiting the AMS Hall of Prevessin with Prof. Samuel Ting from the MIT.

  11. Elecciones consulares en la República romana: control y manipulación

    OpenAIRE

    Muñiz Coello, Joaquín

    2013-01-01

    Tratamos en este artículo sobre la naturaleza de la autoridad del magistrado que preside los comicios electorales en la República romana, con relación a la liturgia de las diversas fases de los procesos y los actos previstos en los mismos. Consideramos relevante tratar de explicar las circuntancias de poder e influencia que caracterizaba al oficio, y la pugna que se desataba entre las factiones del senado, bien para colocar a sus candidatos, bien para influir en ...

  12. La teoría de la justicia en La República

    Directory of Open Access Journals (Sweden)

    David Sobrevilla

    1994-06-01

    Full Text Available En este artículo se presenta la teoría platónica de la justicia a nivel colectivoe individual en La República, siguiéndose los lineamientos del artículode G. Vlastos, "Justice and Happiness in theRepublic" (1971 . Pesea que se haya objetado a esta teoría de diversas maneras, ella aparece como habiendo iniciado la tradición utópica occidental de reflexión sobre elEstado justo.

  13. La democracia parlamentaria en la República de Weimar: entre el mito y la realidad

    OpenAIRE

    1998-01-01

    El artículo examina las principales teorías sobre el fracaso de la República de Weimar y el ascenso del nacional socialismo y llama la atención sobre la necesidad de estudiar en sí el período de Weimar para que, al margen de mitos de todo tipo, revele las deficiencias ideológicas y culturales de la primera experiencia democrática alemana. This article studies the main theories in relation to the failure of the Weimar Republic and the rise of the Nationalsocialist Dictatorship. Thus it call...

  14. Carreiras políticas e nepotismo na Terceira República francesa (1871-1940)

    OpenAIRE

    Niess,Alexandre

    2012-01-01

    Ainda que possa parecer improvável em um regime baseado no sufrágio universal masculino, as conexões familiares e o nepotismo cumpriram um papel extremamente importante na democracia representativa na Terceira República Francesa (1870-1940). Na verdade, essas práticas continuam importantes em algumas partes da esfera política até hoje. Este artigo examina detalhadamente as conexões e as práticas políticas no departamento de Marne, um espaço político onde vários tipos diferentes de conexões po...

  15. Lightweight Autonomous Underwater Vehicles (AUVs) performing coastal survey operations in REP 10A

    Science.gov (United States)

    Incze, Michael L.

    2011-11-01

    Lightweight Autonomous Underwater Vehicles (AUVs) were developed for Naval Special Warfare (NSW) Group 4 search and survey missions from a commercial AUV baseline (Iver 2) through integration of commercial off-the-shelf (COTS) hardware components, and through software development for enhanced on-board Command and Control functions. The development period was 1 year under a project sponsored by the Office of Naval Research TechSolutions Program Office. Hardware integration was completed by the commercial AUV vendor, OceanServer Technology, Inc., and software development was conducted by the Naval Undersea Warfare Center, Naval Oceanographic Office, and U MASS Dartmouth, with support from hardware and software application providers (YSI, Inc., Imagenex Technology Corp., and CARIS). At the conclusion of the integration and development period, an at-sea performance evaluation was scheduled for the Lightweight NSW AUVs with NSWG-4 personnel. The venue for this evaluation was the NATO exercise Recognized Environmental Picture 10A (REP 10A), hosted by Marinha Portuguesa, and coordinated by the Faculdade de Engenharia-Universidade do Porto. REP 10A offered an opportunity to evaluate the performance of the new AUVs and to explore the Concept of Operations (CONOPS) for employing them in military survey operations in shallow coastal waters. Shore- and ship-launched scenarios with launch/recovery by a single operator in a one-to-many coordinated survey, on-scene data product generation and visualization, data push to Reach Back Cells for product integration and enhancement, and survey optimization to streamline survey effort and timelines were included in the CONOPS review. Opportunities to explore employment of hybrid AUV fleets in Combined Force scenarios were also utilized. The Naval Undersea Warfare Center, Marinha Portuguesa, the Faculdade de Engenharia-Universidade do Porto, and OceanServer Technology, Inc., were the primary participants bringing in-water resources to

  16. El separatismo en la República Popular China : El caso de los Uigures en Xinjiang

    OpenAIRE

    Sarli, Corina; Schiaffi, Belén

    2010-01-01

    Con la intención de profundizar el estudio de diferentes aspectos de las relaciones internacionales, se considera relevante analizar aquellos movimientos separatistas que trascienden los conflictos propios de un Estado. En este sentido, es nuestra intención centrarnos en uno de los conflictos internos mas importantes que esta atravesando el Estado que hoy es considerado la segunda economía mundial, la República Popular China (RPCh). Así, el objetivo de este trabajo es estudiar el conflicto...

  17. Liberalismo y democracia en Argentina. El estudio de un caso: Ernesto Nelson: ¿Un educador del Estado en contra del Estado?

    Directory of Open Access Journals (Sweden)

    Alejandro Herrero

    2006-01-01

    Full Text Available En el presente trabajo estudiamos un aspecto de la trayectoria de Ernesto Nelson (1873-1959, acotado, además, a los años de su pertenencia a la Universidad Nacional de La Plata, examinando su proyecto universitario que se diferencia tanto de la política que se implementa en esa casa de estudios por su fundador y presidente Joaquín V. González (gobierna tres períodos consecutivos: 1908-1918, como de la nueva política que nace con la Reforma Universitaria (1918. Nelson afirma, desde un enfoque liberal, que el Estado es la causa principal de la decadencia del sistema universitario argentino, adoptando, de este modo, una posición que lo separa de unos (liberales conservadores y de otros (los reformistas del 18.

  18. 好汉当年勇 BILL WALTON

    Institute of Scientific and Technical Information of China (English)

    chinshen

    2011-01-01

    "拉塞尔(Bill Russell)是伟大的盖帽手,张伯伦(Wilt Chamberlain)则在进攻方面非常优异,他们都是很棒的中锋。"前开拓者教练兰姆西(Jack Ramsay)这么说。"但他们办得到的,沃顿(Bill Walton)通通都做得到……"

  19. Comparison groups on bills: Automated, personalized energy information

    Energy Technology Data Exchange (ETDEWEB)

    Iyer, Maithili; Kempton, Willett; Payne, Christopher

    2006-07-01

    A program called ``Innovative Billing?? has been developed to provide individualized energy information for a mass audience?the entireresidential customer base of an electric or gas utility. Customers receive a graph on the bill that compares that customer?s consumption with othersimilar customers for the same month. The program aims to stimulate customers to make ef?ciency improvements. To group as many as severalmillion customers into small ``comparison groups??, an automated method must be developed drawing solely from the data available to the utility.This paper develops and applies methods to compare the quality of resulting comparison groups.A data base of 114,000 customers from a utility billing system was used to evaluate Innovative Billing comparison groups, comparing fouralternative criteria: house characteristics (?oor area, housing type, and heating fuel); street; meter read route; billing cycle. Also, customers wereinterviewed to see what forms of comparison graphs made most sense and led to fewest errors of interpretation. We ?nd that good qualitycomparison groups result from using street name, meter book, or multiple house characteristics. Other criteria we tested, such as entire cycle, entiremeter book, or single house characteristics such as ?oor area, resulted in poor quality comparison groups. This analysis provides a basis forchoosing comparison groups based on extensive user testing and statistical analysis. The result is a practical set of guidelines that can be used toimplement realistic, inexpensive innovative billing for the entire customer base of an electric or gas utility.

  20. Senate Republican leadership releases revised ACA repeal and replace bill

    Directory of Open Access Journals (Sweden)

    Moore NS

    2017-07-01

    Full Text Available No abstract available. Article truncated after first 150 words. Today, the Senate Republican leadership released a revised version of a bill to repeal and replace the Affordable Care Act (ACA. The new bill draft includes an amendment sponsored by Sen. Cruz (R-TX that permits insurers to offer health insurance plans on the ACA exchanges that do not cover the ACA’s 10 essential health benefits (EHB as long as they offer at least one other plan that provides full coverage of EHB’s. The bill also includes more funding for opioid addiction and for state initiatives to reduce insurance premiums and additionally, some flexibility for state Medicaid funding in the event of a public health crisis. The bill must still receive a cost estimate from the Congressional Budget Office (CBO, which will include the impact of the bill on insurance coverage levels, expected out Monday. The ATS remains deeply concerned about the bill because under the Cruz proposal, insurance coverage costs …

  1. Impact of the Balance Billing Ban on California Emergency Providers

    Directory of Open Access Journals (Sweden)

    Bing Pao

    2014-07-01

    Full Text Available Introduction: The objective of this study was to examine reimbursement trends for emergency provider professional services following the balance billing ban in California. Methods: We conducted a blinded web-based survey to collect claims data from emergency providers and billing companies. Members of the California Chapter of the American College of Emergency Physicians (California ACEP reimbursement committee were invited to participate in the survey. We used a convenience sample of claims to determine payment rates before and after the balance billing ban. Results: We examined a total of 55,243 claims to determine the percentage of charges paid before and after the balance billing ban took effect on October 15, 2008. The overall reduction in percentage of charges paid was 13% in the first year and 19% in the second year following the balance billing ban. The average percentage of charges paid by health plans decreased from 91% to 86% from 2008 to 2010. Payments by risk-bearing organizations decreased from 72% to 46% of charges during the same time frame. Conclusion: Payment rates by subcontracted risk-bearing organizations for non-contracted emergency department professional services declined significantly following the balanced billing ban whereas payment rates by health plans remained relatively stable.

  2. Impact of the balance billing ban on California emergency providers.

    Science.gov (United States)

    Pao, Bing; Riner, Myles; Chan, Theodore C

    2014-07-01

    The objective of this study was to examine reimbursement trends for emergency provider professional services following the balance billing ban in California. We conducted a blinded web-based survey to collect claims data from emergency providers and billing companies. Members of the California Chapter of the American College of Emergency Physicians (California ACEP) reimbursement committee were invited to participate in the survey. We used a convenience sample of claims to determine payment rates before and after the balance billing ban. We examined a total of 55,243 claims to determine the percentage of charges paid before and after the balance billing ban took effect on October 15, 2008. The overall reduction in percentage of charges paid was 13% in the first year and 19% in the second year following the balance billing ban. The average percentage of charges paid by health plans decreased from 91% to 86% from 2008 to 2010. Payments by risk-bearing organizations decreased from 72% to 46% of charges during the same time frame. Payment rates by subcontracted risk-bearing organizations for non-contracted emergency department professional services declined significantly following the balanced billing ban whereas payment rates by health plans remained relatively stable.

  3. Murals speak louder than words : Nelson Rockefeller - Diego Rivera clash and making of the US art culturre during the 1930's

    OpenAIRE

    Pınar, Gözde

    2013-01-01

    Ankara : The Department of History, İhsan Doğramacı Bilkent Univ., 2013. Thesis (Master's) -- Bilkent University, 2013. Includes bibliographical references. This study examines part of the US art culture, more specifically the transformation it underwent during the 1930’s through the case study, Nelson Rockefeller-Diego Rivera clash. This clash has such an importance in the US history as it triggered the questions of function in art in the US. The study mainly argues that by...

  4. Choice of speciality amongst first-year medical students in the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal

    OpenAIRE

    Onyemaechi O. Azu; Edwin Naidu; Jesse Naidu

    2013-01-01

    Background: Trends in career choice amongst medical graduates have considerable implications for the percentage of the workforce available for training.Objective: To investigate and review factors affecting career choice by undergraduate firstyearmedical students.Method: This was a cross-sectional study using a closed-ended, semi-structured surveyinstrument. Two hundred and four questionnaires were administered to all first-year medical students at the Nelson R. Mandela School of Medicine in ...

  5. True Grit: In Tracking down the Real Story of a Legendary Hero of the Old West, Vaunda Micheaux Nelson also Nabbed the Coretta Scott King Award

    Science.gov (United States)

    Fleishhacker, Joy

    2010-01-01

    When Vaunda Micheaux Nelson donned a black Stetson to become the biographer of Deputy U.S. Marshal Bass Reeves, she had no idea that her square-shooting book about an unsung African-American hero of the Old West would win over a posse of fans and earn her the prestigious 2010 Coretta Scott King (CSK) Author Award. "Bad News for Outlaws"…

  6. International conference on "Photosynthesis Research for Sustainability-2016" : In honor of Nathan Nelson and Turhan Nejat Veziroğlu.

    Science.gov (United States)

    Tsygankov, Anatoly A; Allakhverdiev, Suleyman I; Tomo, Tatsuya; Govindjee

    2017-02-01

    During June 19-26, 2016, an international conference ( http://photosynthesis2016.cellreg.org/ ) on "Photosynthesis Research for Sustainability-2016" was held in honor of Nathan Nelson and Turhan Nejat Veziroğlu at the Institute of Basic Biological Problems, Russian Academy of Sciences, formerly Institute of Photosynthesis, Academy of Sciences of the USSR, Pushchino, Russia. Further, this conference celebrated the 50th anniversary of the Institute. We provide here a brief introduction and key contributions of the two honored scientists, and then information on the conference, on the speakers, and the program. A special feature of this conference was the awards given to several young investigators, who are recognized in this Report. Several photographs are included to show the excellent ambience at this conference. We invite the readers to the next conference on "Photosynthesis and Hydrogen Energy Research for Sustainability-2017", which will honor A.S. Raghavendra (of University of Hyderabad), William Cramer (of Purdue University) and Govindjee (of University of Illinois at Urbana-Champaign); it will be held during the Fall of 2017 (from October 30 to November 4), at the University of Hyderabad, Hyderabad, India. See .

  7. DIMENSÕES (ESTÉTICAS E POLÍTICAS DA PAIXÃO ENTRE SIMONE E NELSON

    Directory of Open Access Journals (Sweden)

    Daniele Nunes Henrique Silva

    2016-04-01

    Full Text Available Resumo O objetivo deste trabalho é tecer uma reflexão sobre as paixões humanas numa perspectiva histórico-cultural, com base nas contribuições de Vigotski, em diálogo com proposições de Espinosa e Bakhtin. Tomamos comolocus central de análise as narrativas de Frain sobre cartas trocadas entre os amantes Simone de Beauvoir e Nelson Algren, que dão visibilidade aos desdobramentos éticos-políticos da paixão. Exploramos a paixão em sua dimensão política, histórico-cultural e seus impactos na configuração experiencial do drama - choque de sistemas que envolve os protagonistas (pessoas sociais que vivem na carne o enlace. A conclusão aponta para um deslocamento epistemológico no tratamento da paixão que nos permite questionar duas das dicotomias que marcam o pensamento psicológico: a separação entre o social e o pessoal; a razão e emoção. Ao final, assinalamos o estudo das paixões com foco na ação mobilizadora dos processos criadores, para além da passividade apaixonada.

  8. The complete mitochondrial genome of the gall-forming fly, Fergusonina taylori Nelson and Yeates (Diptera: Fergusoninidae).

    Science.gov (United States)

    Nelson, Leigh A; Cameron, Stephen L; Yeates, David K

    2011-10-01

    The monogeneric family Fergusoninidae consists of gall-forming flies that, together with Fergusobia (Tylenchida: Neotylenchidae) nematodes, form the only known mutualistic association between insects and nematodes. In this study, the entire 16,000 bp mitochondrial genome of Fergusonina taylori Nelson and Yeates was sequenced. The circular genome contains one encoding region including 27 genes and one non-coding A+T-rich region. The arrangement of the protein-coding, ribosomal RNA (rRNA) and transfer RNA (tRNA) genes was the same as that found in the ancestral insect. Nucleotide composition is highly A+T biased. All of the protein initiation codons are ATN, except for nad1 which begins with TTT. All 22 tRNA anticodons of F. taylori match those observed in Drosophila yakuba, and all form the typical cloverleaf structure except for tRNA-Ser((AGN)) which lacks a dihydrouridine (DHU) arm. Secondary structural features of the rRNA genes of Fergusonina are similar to those proposed for other insects, with minor modifications. The mitochondrial genome of Fergusonina presented here may prove valuable for resolving the sister group to the Fergusoninidae, and expands the available mtDNA data sources for acalyptrates overall.

  9. Textural and Geochemical Characteristics of Proglacial Sediments:A Case Study in the Foreland of the Nelson Ice Cap, Antarctica

    Institute of Scientific and Technical Information of China (English)

    LIU Xiaodong; SUN Liguang; YIN Xuebin

    2004-01-01

    This paper presents a detailed study on the textural and geochemical characteristics of the proglacial sediments near the edge of modem Nelson Ice Cap, Antarctica. The grain size distributions of the proglacial sediments are characteristic of glacigenic deposits, but very different from those of aeolian and lacustrine sediments. Moreover, the grain size distributions of the proglacial sediments are fractal with a dimension of about 2.9, and the fractal dimensions can be used as another summary statistical parameter for quantifying the relative amounts of coarse and fine materials.Correlations between the absolute element abundances of the proglacial sediments are very weak due to mineral partitioning and other effects of glacial processes, but correlations between the element/Rb ratios are statistically significant. This finding indicates that element/Rb ratios can be used to reduce or eliminate the effects of glacial processes,evaluate geochemical data and determine the sediment provenance in the foreland of Antarctic glacier. Comparisons on the element concentrations among different environments suggest that the proglaciai sediments are derived predominantly from local bedrocks and appear to be natural in origin. Thus these natural sediments can be used to study chemical weathering in the progiacial foreland of modern glacier.

  10. Mouse fibroblast L929 cells are less permissive to infection by Nelson Bay orthoreovirus compared to other mammalian cell lines.

    Science.gov (United States)

    Mok, Lawrence; Wynne, James W; Grimley, Samantha; Shiell, Brian; Green, Diane; Monaghan, Paul; Pallister, Jackie; Bacic, Antony; Michalski, Wojtek P

    2015-07-01

    In recent years, bats have been identified as a natural reservoir for a diverse range of viruses. Nelson Bay orthoreovirus (NBV) was first isolated from the heart blood of a fruit bat (Pteropus poliocephalus) in 1968. While the pathogenesis of NBV remains unknown, other related members of this group have caused acute respiratory disease in humans. Thus the potential for NBV to impact human health appears plausible. Here, to increase our knowledge of NBV, we examined the replication and infectivity of NBV using different mammalian cell lines derived from bat, human, mouse and monkey. All cell lines supported the replication of NBV; however, L929 cells showed a greater than 2 log reduction in virus titre compared with the other cell lines. Furthermore, NBV did not induce major cytopathic effects in the L929 cells, as was observed in other cell lines. Interestingly, the related Pteropine orthoreoviruses, Pulau virus (PulV) and Melaka virus (MelV) were able to replicate to high titres in L929 cells but infection resulted in reduced cytopathic effect. Our study demonstrates a unique virus-host interaction between NBV and L929 cells, where cells effectively control viral infection/replication and limit the formation of syncytia. By elucidating the molecular mechanisms that control this unique relationship, important insights will be made into the biology of this fusogenic virus.

  11. Realidades de la independencia del Banco de la República Realities of the independence of the Banco de la República

    Directory of Open Access Journals (Sweden)

    Kalmanovitz Salomón

    1997-12-01

    Full Text Available La autonomía del banco central Colombiano es parte del proceso político que buscaba reducir el exagerado centralismo colombiano. Sin embargo el poder central no fue limitado en grado suficiente por la Constitución del 1991, como muestra el hecho de que el Ministro de Hacienda es el Presidente de la Junta Directiva del Banco de la República. Esto no sucede en ningun banco independiente del mundo por que los objetivos del gobierno son distintos a los del Banco Central y el Ministerio de Finanzas podría desviar al Banco de sus objetivos antiinflacionarios fundamentales. En Colombia, el gobierno no sólo participa en la Junta para acomodar sus múltiples objetivos sino también hace opocisión pública a la política monetaria y así la desacredita. El articulo plantea que el principio de no reelección hace que el horizonte de tiempo sea muy corto para que el gobierno coseche los frutos de una política de estabilización. El gobierno tiende a gastar en exceso para mejorar su imagen pública y el desajuste lo tiene que enfrentar el gobierno siguiente. De modo que la coordinación entre el Banco Central y el gobierno se torna muy conflictiva.The autonomy of the Central Bank of Colombia is part of a political process which seeks to reduce Colombia' s exaggerated centralismo However, central power was not limited to a sufficient degree by the Constitution of 1991, as demonstrated by the fact that the Minister of Finance is the President of the Board of Directors of the Banco de la República. This does not happen in any independent bank in the world, because the objectives of the government are different from those of the central bank, and the Minister of Finance could divert the Bank away from its fundamental anti-inflationary objectives. This article proposes that the principle of no reelection makes the time horizon very short for the government to reap the fruits of a stabilization policy. The government tends to spend in excess in order to

  12. Public submissions on the Uganda national biotechnology and biosafety bill, 2012 reveal consensus for Uganda legislators to pass the bill

    Directory of Open Access Journals (Sweden)

    Clet Wandui Masiga

    2015-10-01

    Full Text Available The Cartagena Protocol on Biosafety to the Convention on Biological Diversity is an internationally binding instrument addressing issues of biosafety. Biosafety refers to the need to protect human health and the environment from the possible adverse effects of the products of modern biotechnology. Accordingly all countries to the convention are required to put in place regulatory mechanisms to enhance the safety of biotechnology in the context of the Convention’s overall goal of reducing all potential threats to biological diversity, while taking into account the risks to human health. Therefore each country party to the convention has its own procedures to enact laws to guide the safe use of biotechnology. In Uganda the process involves the drafting of the bill by the first parliamentary counsel, approval by cabinet, first reading at the parliament, committal to the responsible parliamentary sessional committee, tabling of the bill for public hearing, consultations, and final approval. In Uganda, the Committee on Science and Technology is responsible for the Biosafety Bill. In March 2013, the Committee tabled the bill for public hearing and submissions from public institutions. There were comments supporting the passage of the Bill and comments in objection.The reasons for objection are mainly due to precaution, speculation, lack of knowledge about biotechnology and biosafety, and alleged influence from biosafety entrepreneurs. This article reviews these public views, revealing controversy and possible consensus to pass the bill.

  13. Estado actual de la odontopediatría en la República Mexicana

    Directory of Open Access Journals (Sweden)

    Enrique E .-Huitzil-Muñóz

    2012-02-01

    Full Text Available La odontología pediátrica satisface un propósito muy especial con respecto de las especialidades odontológicas orientada a la prevención y curación de las enfermedades del sistema estomatognático durante la infancia y considerada como una especialidad muy completa y relativamente nueva se realiza una revisión acerca de la historia de la odontología pedíatrica en el mundo y en especial en México, recopilando información importante acerca de las instituciones universitarias que cuentan en su curricula con la especialidad, certificación y zonas de ubicación en la República Mexicana. Conclusiones: De acuerdo a las regiones de la República Mexicana en las que se encuentran ubicados los diversos posgrados, se concluye que de un total de 30 universidades que cuentan con la especialidad o maestría en odontopediatría, existen 7 en la denominada región centro y golfo y 6 en la región México D.F., estos datos concuerdan con el elevado número de habitantes que habitan esas regiones y que necesitan atención odontopediátrica cubriendo así la alta demanda del servicio por parte de los odontólogos posgraduados egresados.

  14. Averróis e a República de Platão

    Directory of Open Access Journals (Sweden)

    Pereira, Rosalie Helena de Souza

    2007-01-01

    Full Text Available Sobre República é o único comentário de uma obra de Platão deixado por Averróis, o comentador por antonomásia, diga-se de Aristóteles. Embora se tenha perdido o original árabe, a teles. Embora se tenha perdido o original árabe, a posteridade recebeu uma versão hebraíca e duas latinas. O comentário (ou paráfrase a República de Platão pode ser considerado uma obra original - divida em três livros - já que apenas um terço dela corresponde ao texto platônico. Além de apresentar conceitos aristotélicos retirados da Ética Nicomaquéia e de obras políticas de Al-Farabi, Averróis apresenta reflexões próprias e faz críticas à sociedade em que vive

  15. Four types of (super)conformal mechanics: D-module reps and invariant actions

    CERN Document Server

    Holanda, N L

    2014-01-01

    (Super)conformal mechanics in one dimension is induced by parabolic or hyperbolic/trigonometric transformations, either homogeneous (for a scaling dimension $\\lambda$) or inhomogeneous (at $\\lambda=0$, with $\\rho$ an inhomogeneity parameter). Four types of inequivalent (super)conformal actions are thus obtained. With the exclusion of the homogeneous parabolic case, dimensional constants are present. Both the inhomogeneity and the insertion of $\\lambda$ generalize the construction of Papadopoulos [CQG 30 (2013) 075018; arXiv:1210.1719]. Inhomogeneous $D$-module reps are presented for the $d=1$ superconformal algebras $osp(1|2)$, $sl(2|1)$, $B(1,1)$ and $A(1,1)$. For centerless superVirasoro algebras $D$-module reps are presented (in the homogeneous case for ${\\cal N}=1,2,3,4$; in the inhomogeneous case for ${\\cal N}=1,2,3$). The four types of $d=1$ superconformal actions are derived for ${\\cal N}=1,2,4$ systems. When ${\\cal N}=4$, the homogeneously-induced actions are $D(2,1;\\alpha)$-invariant ($\\alpha$ is cri...

  16. Four types of (super)conformal mechanics: D-module reps and invariant actions

    Energy Technology Data Exchange (ETDEWEB)

    Holanda, N.L.; Toppan, F., E-mail: linneu@cbpf.br, E-mail: toppan@cbpf.br

    2014-03-15

    (Super)conformal mechanics in one dimension is induced by parabolic or hyperbolic/trigonometric transformations, either homogeneous (for a scaling dimension λor inhomogeneous (at λ = 0, with ρ an inhomogeneity parameter). Four types of inequivalent (super)conformal actions are thus obtained. With the exclusion of the homogeneous parabolic case, dimensional constants are present. Both the inhomogeneity and the insertion of λ generalize the construction of Papadopoulos [CQG 30 (2013) 075018; arXiv:1210.1719]. Inhomogeneous D-module reps are presented for the d = 1 superconformal algebras osp(1∣2), sl(2∣1), B(1, 1) and A(1, 1). For centerless super Virasoro algebras D-module reps are presented (in the homogeneous case for N = 1; 2; 3; 4; in the inhomogeneous case for N = 1, 2, 3). The four types of d = 1 superconformal actions are derived for N = 1, 2, 4 systems. When N = 4, the homogeneously-induced actions are D(2, 1; α)-invariant (α is critically linked to λ); the inhomogeneously-induced actions are A(1, 1)-invariant. In d = 2, for a single bosonic field, the homogeneous transformations induce a conformally invariant power-law action, while the inhomogeneous transformations induce the conformally invariant Liouville action. (author)

  17. La segunda república: un discurso esquivo en la izquierda colombiana

    Directory of Open Access Journals (Sweden)

    Miguel Antonio Espinosa Rico

    2013-01-01

    Full Text Available El artículo trata sobre el estado actual de la realidad de la izquierda colombiana y su relación con la crisis del estado moderno colombiano. Se argumenta con FalsBorda (2001 y otros, que la globalización constituye un tema central para la consolidación del capitalismo colombiano, considerando con los autores revisados que el Estado Moderno representa la estructura sobre la cual se yergue el capitalismo en Occidente, pero que en Latinoamérica, y en especial, en la República Neogranadina, sienta las bases para la perpetuación del sistema. Analiza el sistema de división territorial colombiano para establecer premisas de dominio del régimen capitalista sobre el ciudadano común. Se concluye que el nuevo país solo es posible con sueño de la izquierda de la Segunda República, que reivindica las regiones como pilar fundamental para la dignidad del pueblo colombiano.

  18. Postsymbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola

    Science.gov (United States)

    Van Ham, Roeland C. H. J.; González-Candelas, Fernando; Silva, Francisco J.; Sabater, Beatriz; Moya, Andrés; Latorre, Amparo

    2000-01-01

    Buchnera aphidicola is an obligate, strictly vertically transmitted, bacterial symbiont of aphids. It supplies its host with essential amino acids, nutrients required by aphids but deficient in their diet of plant phloem sap. Several lineages of Buchnera show adaptation to their nutritional role in the form of plasmid-mediated amplification of key-genes involved in the biosynthesis of tryptophan (trpEG) and leucine (leuABCD). Phylogenetic analyses of these plasmid-encoded functions have thus far suggested the absence of horizontal plasmid exchange among lineages of Buchnera. Here, we describe three new Buchnera plasmids, obtained from species of the aphid host families Lachnidae and Pemphigidae. All three plasmids belong to the repA1 family of Buchnera plasmids, which is characterized by the presence of a repA1-replicon responsible for replication initiation. A comprehensive analysis of this family of plasmids unexpectedly revealed significantly incongruent phylogenies for different plasmid and chromosomally encoded loci. We infer from these incongruencies a case of horizontal plasmid transfer in Buchnera. This process may have been mediated by secondary endosymbionts, which occasionally undergo horizontal transmission in aphids. PMID:10984505

  19. RepExplore: addressing technical replicate variance in proteomics and metabolomics data analysis.

    Science.gov (United States)

    Glaab, Enrico; Schneider, Reinhard

    2015-07-01

    High-throughput omics datasets often contain technical replicates included to account for technical sources of noise in the measurement process. Although summarizing these replicate measurements by using robust averages may help to reduce the influence of noise on downstream data analysis, the information on the variance across the replicate measurements is lost in the averaging process and therefore typically disregarded in subsequent statistical analyses.We introduce RepExplore, a web-service dedicated to exploit the information captured in the technical replicate variance to provide more reliable and informative differential expression and abundance statistics for omics datasets. The software builds on previously published statistical methods, which have been applied successfully to biomedical omics data but are difficult to use without prior experience in programming or scripting. RepExplore facilitates the analysis by providing a fully automated data processing and interactive ranking tables, whisker plot, heat map and principal component analysis visualizations to interpret omics data and derived statistics. Freely available at http://www.repexplore.tk enrico.glaab@uni.lu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

  20. Generation of RGB-D data for SLAM using robotic framework V-REP

    Science.gov (United States)

    Gritsenko, Pavel S.; Gritsenko, Igor S.; Seidakhmet, Askar Zh.; Abduraimov, Azizbek E.

    2017-09-01

    In this article, we will present a methodology to debug RGB-D SLAM systems as well as to generate testing data. We have created a model of a laboratory with an area of 250 m2 (25 × 10) with set of objects of different type. V-REP Microsoft Kinect sensor simulation model was used as a basis for robot vision system. Motion path of the sensor model has multiple loops. We have written a program in V-Rep native language Lua to record data array from the Microsoft Kinect sensor model. The array includes both RGB and Depth streams with full resolution (640 × 480) for every 10 cm of the path. The simulated path has absolute accuracy, since it is a simulation, and is represented by an array of transformation matrices (4 × 4). The length of the data array is 1000 steps or 100 m. The path simulates frequently occurring cases in SLAM, including loops. It is worth noting that the path was modeled for a mobile robot and it is represented by a 2D path parallel to the floor at a height of 40 cm.

  1. La “República de Colombia” del Libertador Simón Bolívar

    Directory of Open Access Journals (Sweden)

    Carlos Uribe Celis

    2013-01-01

    Full Text Available Este ensayo traza el recorrido hist rico de la Rep blica de Colombia como la visualiz , la program y le dio vida el Libertador Sim n Bol var. La Rep blica de Colombia de Bol var era la uni n de lo que despu s constituyeron tres rep blicas distintas, hoy conocidas como Venezuela, Colombia y Ecuador. Bol var aprovecha parcialmente una idea original de Miranda (la Colombeia del sue o continental del ?recursor?, y este ensayo ilustra la con?guraci n del proyecto bolivariano, desde sus comienzos ajenos hasta la disoluci n del mismo, lo que pr cticamente coincide con la muerte del Libertador. La historia de Colombia se ubica aqu en el contexto de la lucha bolivariana por la Independencia del norte y centro de Suram rica.

  2. Identification of new isolates of Bacillus thuringiensis using rep-PCR products and d-endotoxin electron microscopy

    Directory of Open Access Journals (Sweden)

    Lima A.S.G.

    2002-01-01

    Full Text Available PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic and ERIC (Enterobacterial Repetitive Intergenic Consensus sequences (rep-PCR found within the genome of the bacterium Bacillus thuringiensis, with the purpose to analyze the genetic similarities among 56 subspecies samples and 95 field isolates. The PCR products were analyzed by EB-AGE (ethidium bromide-agarose electrophoresis and then submitted to banding comparisons, based on the Phyllip software algorithm. When the banding similarities were considered for comparison purposes among all the strains, the phylogenic tree patterns varied according to the rep-PCR primers considered, but, from a broader point of view, the ERIC sequences produced better results, which, together with electron microscopy analysis of the released parasporal bodies and colony morphology characteristics, allowed to detect two possible new subspecies of B. thuringiensis.

  3. Identification of new isolates of Bacillus thuringiensis using rep-PCR products and delta-endotoxin electron microscopy

    Directory of Open Access Journals (Sweden)

    A.S.G. Lima

    2002-01-01

    Full Text Available PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic and ERIC (Enterobacterial Repetitive Intergenic Consensus sequences (rep-PCR found within the genome of the bacterium Bacillus thuringiensis, with the purpose to analyze the genetic similarities among 56 subspecies samples and 95 field isolates. The PCR products were analyzed by EB-AGE (ethidium bromide-agarose electrophoresis and then submitted to banding comparisons, based on the Phyllip software algorithm. When the banding similarities were considered for comparison purposes among all the strains, the phylogenic tree patterns varied according to the rep-PCR primers considered, but, from a broader point of view, the ERIC sequences produced better results, which, together with electron microscopy analysis of the released parasporal bodies and colony morphology characteristics, allowed to detect two possible new subspecies of B. thuringiensis.

  4. Desplazando al Rey en la escuela de la nueva nación mexicana: "el catecismo de República"

    Directory of Open Access Journals (Sweden)

    María Adelina ARREDONDO LÓPEZ

    2010-03-01

    Full Text Available RESUMEN: Este artículo estudia cómo un texto escolar, como el catecismo político de la nueva República de México, contribuye a desplazar de la escuela primaria la presencia colonial española, representada en el Rey, por nuevas imágenes de las instituciones de la naciente República de México. ABSTRACT: This paper studie how a textbook, the politic catechism of Mexican Republic, contribute to suplant the Spanish King instead the new images of the recent Mexican Republic during the emancipation process.

  5. Impact of Capsid Conformation and Rep-Capsid Interactions on Adeno-Associated Virus Type 2 Genome Packaging

    OpenAIRE

    Bleker, Svenja; Pawlita, Michael; Kleinschmidt, Jürgen A.

    2006-01-01

    Single-stranded genomes of adeno-associated virus (AAV) are packaged into preformed capsids. It has been proposed that packaging is initiated by interaction of genome-bound Rep proteins to the capsid, thereby targeting the genome to the portal of encapsidation. Here we describe a panel of mutants with amino acid exchanges in the pores at the fivefold axes of symmetry on AAV2 capsids with reduced packaging and reduced Rep-capsid interaction. Mutation of two threonines at the rim of the fivefol...

  6. Presencia y bioacumulación de productos de cuidado personal en corales marinos de República Dominicana

    OpenAIRE

    De León Peguero, Ana Esther

    2016-01-01

    El objetivo del proyecto a desarrollar es determinar la presencia de determinados aditivos orgánicos que se utilizan en productos de cuidado personal como champú, gel de baño, maquillaje, cremas solares, etc, en aguas y arrecifes de coral de la República Dominicana. Recientemente se ha documentado que la presencia de este tipo de contaminantes es responsable del blanqueamiento de los corales en zonas del Pacífico y dada la preocupación creciente en la República. Dominicana por el mal estado ...

  7. Em busca do despertar: o fortalecimento da sociedade civil angolana após a Segunda República

    Directory of Open Access Journals (Sweden)

    Rodrigo de Souza Pain

    2006-01-01

    passagem da Primeira República, caracterizada por um Estado de Partido Único, por uma economia planificada e inspirada nos ideais marxistas e leninistas; para a Segunda República, ou seja, para uma economia de mercado, multipartidária, explicitando as adversidades advindas das diversas realidades sociais, políticas e culturais do espaço territorial angolano resultante do processo de colonização, para a formação e consolidação da democracia e da sociedade civil em Angola.

  8. Iberia : capital federal de la IIª República Española (Un proyecto de Rubio i Tuduri

    Directory of Open Access Journals (Sweden)

    Carlos Sambricio

    1996-01-01

    Full Text Available A los pocos meses de proclamarse, en 1931, la II República Española, Nicolás Rubio i Tuduri presentaba —en el marco de la Exposición organizada por la Asociación de Arquitectos de Cataluña, celebrada en la barcelonesa Galería Maragall— una propuesta un tanto sorprendente: el proyecto de una nueva Capital Federal de la República Española que él denominaba Iberia.

  9. C3: A comprehensive physician activity and billing tool

    Science.gov (United States)

    Hirschl; Sikina; Keller; Kastle; McConnell; Greenfield; Plachta

    2000-01-01

    Purpose: The Clinical Charge Capture system (C3) was developed at the University of Michigan to increase the efficiency and accuracy with which information about physician activity and billing is tracked in academic medical centers. Description: This Oracle-based, Visual Basic system integrates the operating room scheduling system, transcription database, clinical data repository, referring physician database, and IDX to allow physicians and staff to perform paperless and on-line standard tasks such as preauthorizing procedures; creating a bill which describes the charges for procedures performed along with their supporting diagnoses; identifying inpatient daily care and consult charges; dictating, editing, signing, and providing attestations for procedural and inpatient notes (menu-driven boilerplate notes are used for common procedures); submitting of charges on-line to IDX; and downloading of payment data from IDX. A messaging system between physicians and billing specialists allows questions to be posed regarding coding issues and options. Summary information about charges is presented and the status of the bill as it progresses through the internal review and billing process is demonstrated. Any missing data are flagged such that delivery of a bill is accurate, timely, and complete. Outpatient clinic visit charges are acquired on line using bar code technology with direct download of clinic charges to IDX. Generation of charges and referral letters may be performed immediately following the performance of a procedure or patient encounter or subsequently in the office. Resident activity is also tracked. Finally, search functions are provided which allow the program to serve as a clinical information research database. Results: The time to bill submission for operative procedures in fiscal year 1996 (Pre-C3) when compared to 1999 (Post-C3) decreased in each individual surgical division (See figure)as well as for the overall Department (Total: mean Pre-C3=40 days

  10. The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins.

    Directory of Open Access Journals (Sweden)

    Louise Madsen

    Full Text Available The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors. In addition, p97 plays a central role in degradation of misfolded secretory proteins via the ER-associated degradation pathway. This functional diversity of p97 depends on its association with various cofactors, and to further our understanding of p97 function it is important that these cofactors are identified and analyzed. Here, we isolate and characterize the human protein named Rep8 or Ubxd6 as a new cofactor of p97. Mouse Rep8 is highly tissue-specific and abundant in gonads. In testes, Rep8 is expressed in post-meiotic round spermatids, whereas in ovaries Rep8 is expressed in granulosa cells. Rep8 associates directly with p97 via its UBX domain. We show that Rep8 is a transmembrane protein that localizes to the ER membrane with its UBX domain facing the cytoplasm. Knock-down of Rep8 expression in human cells leads to a decreased association of p97 with the ER membrane and concomitantly a retarded degradation of misfolded ER-derived proteasome substrates. Thus, Rep8 tethers p97 to the ER membrane for efficient ER-associated degradation.

  11. Expression of full-length and truncated Rep genes from Mungbean yellow mosaic virus-Vigna inhibits viral replication in transgenic tobacco.

    Science.gov (United States)

    Shivaprasad, Padubidri V; Thillaichidambaram, P; Balaji, Vasudevan; Veluthambi, Karuppannan

    2006-12-01

    Mungbean yellow mosaic virus-Vigna (MYMV-Vig) is a bipartite geminivirus that causes a severe yellow mosaic disease in blackgram. An assay was developed to study MYMV-Vig replication by agroinoculation of tobacco leaf discs with partial dimers of the virus. This assay, in a non-host model plant, was used to evaluate pathogen-derived resistance contributed by MYMV-Vig genes in transgenic plants. Viral DNA accumulation was optimum in tobacco leaf discs cultured for 10 days after infection with Agrobacterium tumefaciens strain Ach5 containing partial dimers of both DNA A and DNA B of MYMV-Vig. Transgenic tobacco plants with MYMV-Vig genes for coat protein (CP), replication-associated protein (Rep)-sense, Rep-antisense, truncated Rep (T-Rep), nuclear shuttle protein (NSP) and movement protein (MP) were generated. Leaf discs from transgenic tobacco plants, harbouring MYMV-Vig genes, were agroinoculated with partial dimers of MYMV-Vig and analyzed for viral DNA accumulation. The leaf discs from transgenic tobacco plants harbouring CP and MP genes supported the accumulation of higher levels of MYMV-Vig DNA. However, MYMV-Vig accumulation was inhibited in one transgenic plant harbouring the Rep-sense gene and in two plants harbouring the T-Rep gene. Northern analysis of these plants revealed a good correlation between expression of Rep or T-Rep genes and inhibition of MYMV-Vig accumulation.

  12. 16 CFR 308.7 - Billing and collection for pay-per-call services.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Billing and collection for pay-per-call... 1992 § 308.7 Billing and collection for pay-per-call services. (a) Definitions. For the purposes of... transaction. (iv) A reflection on a billing statement of a telephone-billed purchase for a call made to an...

  13. 49 CFR 377.207 - Effect of mailing freight bills or payments.

    Science.gov (United States)

    2010-10-01

    ... Common Carriers, and Household Goods Freight Forwarders § 377.207 Effect of mailing freight bills or payments. (a) Presentation of freight bills by mail. When carriers present freight bills by mail, the time... 49 Transportation 5 2010-10-01 2010-10-01 false Effect of mailing freight bills or payments. 377...

  14. 49 CFR 373.201 - Receipts and bills of lading for freight forwarders.

    Science.gov (United States)

    2010-10-01

    ... REGULATIONS RECEIPTS AND BILLS Freight Forwarders; Bills of Lading § 373.201 Receipts and bills of lading for freight forwarders. Each freight forwarder must issue the shipper a receipt or through bill of lading... therefor on its form with a notation showing the freight forwarder's name, then the freight forwarder, upon...

  15. Bicentennial of the Bill of Rights: An Occasion for Improving Education about Civic Principles and Values.

    Science.gov (United States)

    Patrick, John J.

    1990-01-01

    Identifies four areas of deficiency in understanding and applying the principles of the Bill of Rights. Provides guidelines to improve instruction, emphasizing systematic coverage of Bill of Rights topics; analysis of case studies on Bill of Rights issues; and discussion of Bill of Rights issues in an open classroom environment. (CH)

  16. Iconography and Politics in South Africa: the representation of Nelson Mandela, Thabo Mbeki and Jacob Zuma in cartoons of Zapiro

    Directory of Open Access Journals (Sweden)

    Renata de Paula dos Santos

    2014-12-01

    Full Text Available Mandela’s victory in the 1994 elections in South Africa is a reference point for South African history and represented the transition from apartheid to multiracial democracy. Since then Nelson Mandela (1994-1999, Thabo Mbeki (1999-2008 and Jacob Zuma (2009 - current, occupied the post of president of the country and led, each in its own way, the new direction of the country. During the nearly twenty years of multiracial democracy, one in particular cartoonist, Jonathan Shapiro, popularly known by the pseudonym Zapiro, portrayed the everyday life of this story. In this sense, the objective of this research is to analyze how Zapiro portrayed the political and social aspects, as well as the psychological characteristics of each of the three postapartheid presidents and which social representations are formed from their cartoon production. The choice of Zapiro explained by openly declared his opposition to apartheid and also for being the best known outside South African cartoonist. We elected to cartoon as an object of study because it is an iconographic object constituted by communicative humor, which adds to its constitution arguments transgression of the established order, enabling an analysis of South African history through a critical bias. As methods for the development of the work, we decided to gather historical research, the literature search and analysis of cartooon speech. Among the theoretical frameworks stand out Magnoli (1998, 2009, Jonge (1991 and Carlin (2009 in the South African question; reflections about social representations, we resort to Moscovici (2011 and Jodelet (1993, in the field the cartoon and humor, the references are Miani (2005; 2012, Romualdo (2000 and Eco (1989. With the completion of the analysis, we observed that Zapiro acts in different ways in the construction of the representation of each of the presidents in question and that the cartoonist presents Mandela as a competent leader marked by heroism and

  17. Design and Modeling Billing solution to Next Generation Networks

    CERN Document Server

    Lakhtaria, Kamaljit I

    2010-01-01

    Next generation networks (NGN) services are assumed to be a new revenue stream for both network operators and service providers. New services especially focused on a mobile telecommunications that would be used not only as a communication de vice but also as a personal gateway to order or consume a variety of services and products [1]. This type of advanced services can be accomplished when the adaptability of the packet-networks (Internet) and the quality of service of the circuit switched networks are combined into one network [2]. New challenges appear in the billing of this heterogeneous multi services network. Some examples of such a services and possible solutions about charging and billing are examined in this paper. The first steps of mathematical model for billing are also considered.

  18. Governor vetoes bill that would test sex offenders for HIV.

    Science.gov (United States)

    1998-06-26

    The Governor of Colorado vetoed a bill that gave prosecutors ammunition to bring felony charges against HIV-infected defendants arrested for sex offenses. The bill would have required HIV testing prior to trial for persons accused of crimes involving sexual penetration. Receipt of a positive test could force public health agencies to disclose prior test results for the same person. The veto was made on the assumption that greater harm would be done in the fight against HIV disease by compromising test confidentiality than would be gained in raising prosecutorial power. Additionally, falsely accused defendants, despite a subsequent acquittal, would still have had the confidentiality of their HIV status automatically breached during the prosecutorial process under the vetoed bill.

  19. How sailfish use their bills to capture schooling prey

    DEFF Research Database (Denmark)

    Domenici, P.; Wilson, A.D.M.; Kurvers, R.H.J.M.

    2014-01-01

    The istiophorid family of billfishes is characterized by an extended rostrum or ‘bill’. While various functions (e.g. foraging and hydrodynamic benefits) have been proposed for this structure, until now no study has directly investigated the mechanisms by which billfishes use their rostrum to feed...... on prey. Here, we present the first unequivocal evidence of how the bill is used by Atlantic sailfish (Istiophorus albicans) to attack schooling sardines in the open ocean. Using high-speed video-analysis, we show that (i) sailfish manage to insert their bill into sardine schools without eliciting...... an evasive response and (ii) subsequently use their bill to either tap on individual prey targets or to slash through the school with powerful lateral motions characterized by one of the highest accelerations ever recorded in an aquatic vertebrate. Our results demonstrate that the combination of stealth...

  20. Jamaica National Net-Billing Pilot Program Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Doris, Elizabeth [National Renewable Energy Lab. (NREL), Golden, CO (United States); Stout, Sherry [National Renewable Energy Lab. (NREL), Golden, CO (United States); Peterson, Kimberly [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-12-18

    This technical report discusses the effectiveness of the Jamaica Public Service Company Limited Net-Billing Pilot Program. The National Renewable Energy Laboratory (NREL) collected and analyzed data from a wide range of stakeholders, conducted in-country research, and compared program elements to common interconnection practices to form programmatic recommendations for the Jamaica context. NREL finds that the net-billing pilot program has successfully contributed to the support of the emerging solar market in Jamaica with the interconnection of 80 systems under the program for a total of 1.38 megawatts (MW) at the time of original analysis.

  1. 环境因素对大肠杆菌REP-PCR指纹图谱稳定性影响研究%Effect of environmental factors of REP-PCR fingerprinting patterns stability of Escherichia coil

    Institute of Scientific and Technical Information of China (English)

    韩彦垒; 梁斌; 李冬梅; 苏洁; 关道明; 王耀兵

    2011-01-01

    Escherichia coli is an important indicator in fecal pollution, The E. Coli DN A fingerprinting stability is to restrict one of identifying techniques development of the microbial polluted sources. In order to solve this problem, the E. Coli K12( K12CFP) , which the green fluorescent protein (CFP) plasmid was transformed, were chose to make a research. Its DNA fingerprinting stability was under different environmental factors (temperature,sunlight time and salinity). The results showed that the green fluorescent protein (CFP) did not affect the REP-PCR fingerprinting patterns of E. Coli K12 and the REP-PCR fingerprinting pattern is highly stable under the different environmental factors, temperature, sunlight time and salinity.%大肠杆菌作为粪便污染指示生物,其DNA指纹图谱稳定性是制约微生物污染源识别技术发展的瓶颈之一.本研究采用绿色荧光蛋白基因(GFP)标记后的Escherichia coli K12(K12GFP)为受试菌株,利用REP-PCR方法,对大肠杆菌在不同温度、光照、盐度条件下其DNA指纹图谱的稳定性进行了研究.结果表明,绿色荧光蛋白基因的标记不影响E.coli K12的REP-PCR指纹图谱;且大肠杆菌在不同温度、光照、盐度条件下REP-PCR指纹图谱具有高度的稳定性.

  2. Eficacia publicitaria: El caso de IKEA y 'La República Independiente de Tu Casa'

    OpenAIRE

    Núñez Ramírez, Marta

    2014-01-01

    L'estudi pretén aprofundir en l'àmbit de l'avaluació de l'eficàcia publicitària, a través de l'anàlisi d'un cas concret: l'anunci d'IKEA 'Benvingut a la República Independent de casa teva' de l'any 2006. Primerament, s'intenta explicar en què consisteix el concepte d'eficàcia, es reflexiona sobre la seva relació o no amb les vendes que aconsegueix generar una marca, i s'obren vies sobre criteris d'avaluació útils per a la investigació. S'arriba a una primera observació: la importància dels ob...

  3. Triatoma baccalaureatus: sobre a crise do bacharelismo na Primeira República

    Directory of Open Access Journals (Sweden)

    Ricardo Sontag

    2010-07-01

    Full Text Available Este trabalho pretende abordar a crise do bacharelismo (hegemônico durante o Império nas primeiras décadas do século XX, principalmente por meio da literatura, relacionando-a com as transformações que estavam ocorrendo no ensino e no saber jurídico. Ao longo da Primeira República, à medida que outras figuras passam a ganhar espaço no cenário público (engenheiros, sanitaristas, etc., o bacharelismo passa a ser duramente questionado, aprofundando as críticas que já vinham sendo levadas a cabo no final do século XIX pelo positivismo cientificista; a partir disso, começa a se formar a cultura do tecnicismo jurídico. Palavras-chave: História do Direito. Bacharelismo. Positivismo cientificista. Tecnicismo.

  4. Agripino Nazareth e o movimento operário da Primeira República

    Directory of Open Access Journals (Sweden)

    Aldrin Armstrong Silva Castellucci

    2012-12-01

    Full Text Available Agripino Nazareth (1886-1961 se destacou como liderança socialista do movimento operário brasileiro ao longo da Primeira República. Depois de 1930, passou a integrar os quadros do Ministério do Trabalho e da Justiça do Trabalho, aposentando-se como Procurador do Trabalho no início de 1960 e falecendo no dia 1º de agosto de 1961. Neste artigo, analisaremos o primeiro momento de sua trajetória, quando se associou a outros militantes das mais variadas correntes político-ideológicas, envolvendo-se em movimentos de diversos matizes e assumindo diferentes compromissos.

  5. Site-specific integration by the adeno-associated virus rep protein.

    Science.gov (United States)

    Recchia, Alessandra; Mavilio, Fulvio

    2011-10-01

    Inserting genetic information at precise locations into the human genome has been the goal of gene transfer technology for almost two decades. The spectacular progress of mammalian genetics has led to the development of technology for genome editing and homologous recombination in human somatic cells that is finally approaching efficiency compatible with clinical application. Site-specific integration, or the insertion of genes at known locations by enzymes with target recognition capacity, has progressed slowly but steadily in recent years, and could very well be the basis of the next generation of gene transfer technology. This review focuses on the use of Rep, the replicase/integrase of the adeno-associated virus (AAV), to insert genes at the natural AAV integration site on human chromosome 19. This region (AAVS1) has characteristics that make it an ideal target for somatic transgenesis.

  6. A paradiplomacia financeira no Brasil da República Velha, 1890-1930

    Directory of Open Access Journals (Sweden)

    José Nelson Bessa Maia

    2012-01-01

    Full Text Available Neste artigo, visa-se a analisar um caso de extroversão de governos estaduais no campo do financiamento externo no período da chamada República Velha (1890-1930 no Brasil. Com base na definição de "paradiplomacia financeira", argumenta que a experiência histórica brasileira nesse aspecto teria sido um caso típico de ação paradiplomática. Amplo levantamento estatístico dos empréstimos externos por estados, o resgate das fontes documentais primárias sobre o assunto e a contextualização histórica pertinente dão sustentação à caracterização do período como uma fase de paradiplomacia financeira precoce.

  7. A paradiplomacia financeira no Brasil da República Velha, 1890-1930

    OpenAIRE

    José Nelson Bessa Maia; José Flávio Sombra Saraiva

    2012-01-01

    Neste artigo, visa-se a analisar um caso de extroversão de governos estaduais no campo do financiamento externo no período da chamada República Velha (1890-1930) no Brasil. Com base na definição de "paradiplomacia financeira", argumenta que a experiência histórica brasileira nesse aspecto teria sido um caso típico de ação paradiplomática. Amplo levantamento estatístico dos empréstimos externos por estados, o resgate das fontes documentais primárias sobre o assunto e a contextualização históri...

  8. Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal

    NARCIS (Netherlands)

    Peters, A.K.; Leonards, P.E.G.; Zhao, B.; Bergman, A.; Denison, M.S.; Berg, van den M.

    2006-01-01

    The TEF system for dioxin-like compounds has included assignment of TEF values for mono-ortho polychlorinated biphenyls (MO-PCBs). Small traces of aryl hydrocarbon receptor (AhR)-active impurities could result in artifactually higher relative potency (REP) values. MO-PCBs -105, -118, -156, and -167

  9. 78 FR 53774 - Guide for the Evaluation of Alert and Notification Systems for Nuclear Power Plants, FEMA-REP-10...

    Science.gov (United States)

    2013-08-30

    ... not available when FEMA REP-10 was first developed, such as smartphones and social media. Removes... Design Report) and planning aspects (ANS/Communication Plans) demonstrating the achievement of minimally... proposed policy does not have the force or effect of law. FEMA seeks comment on the proposed policy,...

  10. The OSIRIS Weight of Evidence approach: ITS for the endpoints repeated-dose toxicity (RepDose ITS)

    NARCIS (Netherlands)

    Tluczkiewicz, I.; Batke, M.; Kroese, D.; Buist, H.; Aldenberg, T.; Pauné, E.; Grimm, H.; Kühne, R.; Schüürmann, G.; Mangelsdorf, I.; Escher, S.E.

    2013-01-01

    In the FP6 European project OSIRIS, Integrated Testing Strategies (ITSs) for relevant toxicological endpoints were developed to avoid new animal testing and thus to reduce time and costs. The present paper describes the development of an ITS for repeated-dose toxicity called RepDose ITS which evalua

  11. La lucha contra la discriminación y la apatridia en la República Dominicana

    OpenAIRE

    Bridget WOODING

    2009-01-01

    Tras muchas décadas de migración irregular de haitianos que llegan a la República Dominicana para asentarse y trabajar, existe una población numerosa en situación incierta expuesta a frecuentes discriminaciones y abusos de los derechos humanos.

  12. Mida on vaja teha õpilaskodude arendamiseks? / Ale Sprenk, Karin Saare, Merike Mändla, Mailis Reps...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad Krabi põhikooli direktor, õpilaskodu mõtte algataja Ale Sprenk, Kasari põhikooli direktor Karin Saare, haridus- ja teadusministeeriumi üldharidusosakonna peaekspert Merike Mändla, riigikogu liige, endine haridusminister Mailis Reps ja Otepää gümnaasiumi direktor Aivo Meema

  13. Feature selection and data sampling methods for learning reputation dimensions: The University of Amsterdam at RepLab 2014

    NARCIS (Netherlands)

    Gârbacea, C.; Tsagkias, M.; de Rijke, M.

    2014-01-01

    We report on our participation in the reputation dimension task of the CLEF RepLab 2014 evaluation initiative, i.e., to classify social media updates into eight predefined categories. We address the task by using corpus-based methods to extract textual features from the labeled training data to

  14. Naturaleza jurídica de la Contraloría General de la República

    OpenAIRE

    Murillo, Mauro

    2014-01-01

    Todavía reina una confusión acerca de la naturaleza jurídica de la ContraloríaGeneral  de la República, pese a los 15 años de vigencia del texto constitucional, cuya insuficiente redacción es obviamente la causante del problema.

  15. Molecular characterization of Pasteurella multocida isolates obtained from poultry, ruminant, cats and dogs using RAPD and REP-PCR analysis

    Directory of Open Access Journals (Sweden)

    Hesamaddin Shirzad-Aski

    2016-09-01

    Full Text Available In the present study, Randomly Amplified Polymorphic DNA‌ (RAPD and Repetitive Extragenic Palindromic sequence-based Polymerase Chain Reaction (REP-PCR were used to characterize 131 isolates of Pasteurella multocida, originating from different healthy and diseased animal species obtained from several geographical regions of Iran. The RAPD and REP-PCR generated amplified products in the range of 300 to 3400 bp and 200 to 2850 bp, respectively. Among all of the P. multocida isolates, cluster analysis revealed that 63 clusters and nine untypable isolates and 81 clusters and six untypable isolates were produced with RAPD and REP-PCR methods, respectively. The results indicated that the REP-PCR method showed a slightly higher level of discrimination power in differentiating of P. multocida isolates as compared with RAPD. The results showed that a considerable level of genetic diversity exists among P. multocida isolates even in the isolates with the same animal or geographical origins. There was no host- and region-specific pattern. In addition, the isolates obtained from the healthy and diseased animal did not reveal any correlation genotypic profiles, which could be supported by the hypothesis that P. multocida is a strictly opportunistic pathogen. In conclusion, because of a large amount of genetic heterogeneityin the P. multocida isolates, Pasteurellosis may be caused by different clones in the same herd or animal.

  16. DEMO_REP: A LABS TOOL FOR TEACHING DATA REPLICATION / DEMO_REP: HERRAMIENTA PARA LABORATORIOS EN LA ENSEÑANZA DE RÉPLICA DE DATOS

    Directory of Open Access Journals (Sweden)

    Ileane Martí Pérez

    2013-02-01

    Full Text Available The process of training professionals in information technologies is a key aspect in the development of the country. University Informatics Science is one of the main centers dedicated to this process, also has postgraduate training programs to further advanced topics not mentioned in the pregraduate. One such program is the "DIPLOMADO EN TECNOLOGÍAS DE BASES DE DATOS POSTGRESQL," which has a number of courses to obtain expertise in the subject of databases in PostgreSQL Manager. In this paper show how affects in the understanding of the process of data replication, the use of the software tool "Demo_rep" for laboratory exercises replication. It also describes the main features of software tool.RESUMENEl proceso de formación de los profesionales en tecnologías de la informática es un aspecto clave en el desarrollo del país. La Universidad de las Ciencias Informáticas es uno de los principales centros que se dedica a este proceso, la misma consta de programas de formación postgraduada para profundizar en temas que no aparecen incluidos en los programas analíticos de las asignaturas de pregrado. Uno de estos programas es el “DIPLOMADO EN TECNOLOGÍAS DE BASES DE DATOS POSTGRESQL”, el cual cuenta con una serie de cursos para lograr experticia en la temática de las bases de datos en el gestor PostgreSQL. En el presente trabajo se muestra cómo incide en la comprensión del proceso de la replicación de datos, la utilización de una herramienta informática “Demo_rep” para realizar los ejercicios de laboratorio de réplica. Se describe además las principales funcionalidades de la misma.

  17. Phylogenetic relationships, virulence factors and Rep-PCR epidemiological analysis of E. coli from human sources

    Directory of Open Access Journals (Sweden)

    Simona Caroppo

    2010-06-01

    Full Text Available The potential of Escherichia coli to cause of extra-intestinal infections was studied on a group of 94 clinical isolates. In this work, 32 E. coli isolates from urinary tract infections, 25 from bacteraemia, 12 from low respiratory tract infections, and 25 from the normal commensal flora were characterized for the phylogenetic type, the virulence factors (VFs carriage and the Rep-PCR clonal composition.The B2 phylogenetic type was predominant among the urinary isolates (59%, the B2 and D strains among the haematic isolates (32% and 32%.The A phylogenetic type was predominant among the commensal and the respiratory isolates (52% and 58% respectively.The distribution of the B2 type strains among the urinary isolates and of the D type strains among the faecal isolates was suggesting a urinary-origin for the B2 phylogenetic type isolates found in the blood and a direct faecal derivation for the haematic isolates with D phylogenetic type.Twenty-nine VFs were analyzed.The B2 and D type strains carried a higher burden of VFs than the A and B1 phylogenetic type strains (average of VFs/strain = 8 vs 3. Some of the VFs were homogeneously distributed among the phylogenetic types (fimH, iutA, fyuA, traT. The PAI, papGII, ibeA, KpsMTIII were exclusive of B2 and D phylogenetic type strains, while sfa/foc, focG, cnf1, hlyA and rfc were exclusively observed among the B2 type strains.The clustering analysis by Rep-PCR distinguished two groups of strains, the first including 96.77% of B2 and D type strains, while the second encompassing 91,5% of A and B1 type strains.

  18. Los médicos del exilio repúblicano en Venezuela

    Directory of Open Access Journals (Sweden)

    José Francisco Tinao Martín-Peña

    2009-11-01

    Full Text Available La guerra civil española provocó el exilio de un importante número de científicos e intelectuales. Dentro de ellos numerosos médicos saldrían de España obligados por su defensa de la República o su ideología democrática. Una gran mayoría se establecieron en América Latina. Venezuela es el segundo país donde más facultativos acoge, tras México. En el presente trabajo se analiza cuales fueron las circunstancias históricas que permitieron esta acogida, y se hace referencia a alguna de las personalidades y sus campos de trabajo en su nuevo país de acogida. Dentro de la historia social de la medicina española existe un espacio vacío sobre el exilio médico y sobre la represión interior ejercida físicamente o simplemente como depurados de numerosos médicos que se vincularon de distinto modo con los ideales de modernidad de la República Española.______________ABSTRACT:The Spanish Civil War led to the exile of a large number of scientists and intellectuals. Among them, many doctors escaped from Spain because of their defense of the Republic or their democratic ideology. A large majority were established in Latin America. Venezuela is the second country of welcome, after Mexico. In this paper we analyze what were the historical circumstances that allowed this host, and it is made reference to some personalities and their fields of work in their new host country. Within the social history of Spanish medicine, there is an empty space on the exile of this category and their internal repression or the purged of many doctors linked to the ideals of modernity of the Spanish Republic.

  19. Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI+

    Directory of Open Access Journals (Sweden)

    Fátima eGasset-Rosa

    2015-04-01

    Full Text Available The yeast translation termination factor Sup35p, by aggregating as the [PSI+] prion, enables ribosomes to read-through stop codons, thus expanding the diversity of the Saccharomyces cerevisiae proteome. Yeast prions are functional amyloids that replicate by templating their conformation on native protein molecules, then assembling as large aggregates and fibers. Prions propagate epigenetically from mother to daughter cells by fragmentation of such assemblies. In the N-terminal prion-forming domain, Sup35p has glutamine/asparagine-rich oligopeptide repeats (OPRs, which enable propagation through chaperone-elicited shearing. We have engineered chimeras by replacing the polar OPRs in Sup35p by up to five repeats of a hydrophobic amyloidogenic sequence from the synthetic bacterial prionoid RepA-WH1. The resulting hybrid, [REP-PSI+], i was functional in a stop codon read-through assay in S. cerevisiae; ii generates weak phenotypic variants upon both its expression or transformation into [psi-] cells; iii these variants correlated with high molecular weight aggregates resistant to SDS during electrophoresis; and iv according to fluorescence microscopy, the fusion of the prion domains from the engineered chimeras to the reporter protein mCherry generated perivacuolar aggregate foci in yeast cells. All these are signatures of bona fide yeast prions. As assessed through biophysical approaches, the chimeras assembled as oligomers rather than as the fibers characteristic of [PSI+]. These results suggest that it is the balance between polar and hydrophobic residues in OPRs what determines prion conformational dynamics. In addition, our findings illustrate the feasibility of enabling new propagation traits in yeast prions by engineering OPRs with heterologous amyloidogenic sequence repeats.

  20. A Primeira República Portuguesa (1910-1926: partidos e sistema político

    Directory of Open Access Journals (Sweden)

    Baiôa, Manuel

    2014-04-01

    Full Text Available For historical, organisational, clientelist, violent and constitutional reasons the Portuguese Republican Party became the dominant party in the political system of the Portuguese First Republic (1910-1926. The opposition felt alternation via elections would be difficult to achieve so resorted to violent and unconstitutional practices to reach government. The Portuguese political parties modernised themselves in this period, but failed to turn into mass parties. In major cities they acted as a cadre party and in the rural area as a party of notables. The First Republic failed to take solid steps to democratise the political system were And Portugal remained tied to the liberal and elitist tradition of the nineteenth century, although in a republican version.El Partido Republicano Portugués se convirtió en el partido dominante del sistema político de la Primera República Portuguesa (1910-1926 debido a causas históricas, organizacionales, clientelistas, violentas y constitucionales. La oposición sentía que difícilmente conseguiría la alternancia política a través de elecciones, y por lo tanto, recurre a prácticas violentas e inconstitucionales para llegar al gobierno. Los partidos políticos portugueses se modernizaron en este período, pero no se convirtieron en partidos de masas. En las principales ciudades actuaban como partidos de cuadros y en las zonas rurales como partidos de notables. Durante la Primera República no se dieron pasos consistentes para democratizar el sistema político. Portugal se mantuvo ancorado a la tradición liberal y elitista del siglo XIX, aunque en una versión republicana.

  1. BILLING IS A DEVELOPING MEANS OF BRANDS PROMOTION

    Directory of Open Access Journals (Sweden)

    Vladimir A. Polyakov

    2013-01-01

    Full Text Available The article gives a concept of the billing as a developing means of marketing promotion. Examples of comparative analysis for a rating are considered. The author presents technology of two-factor rating of trade marks on the basis of expert and comparative analysis.

  2. 49 CFR 373.101 - Motor carrier bills of lading.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Motor carrier bills of lading. 373.101 Section 373.101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS RECEIPTS...

  3. Low Frequency Radio Astronomy Summary: A Festschrift For Bill Erickson

    Science.gov (United States)

    Clark, B. G.; Kassim, N. E.; Perez, M. R.

    2005-12-01

    The science and technological issues presented at this workshop in honor of Bill Erickson's 74th birthday, are certainly opening up a new window of astronomical observations at the low end of the radio frequency spectrum. We briefly review some of the contributions concentrating our comments on the topics of science, technology, and history.

  4. House Bill 1079: 2013-14 Student Enrollment Update

    Science.gov (United States)

    West, Jim

    2015-01-01

    Effective July 1, 2003, House Bill (HB) 1079 allows any student, including presumed undocumented students who meet specific criteria, to pay in-state tuition at Washington's public colleges and universities. In addition to meeting certain conditions, the affidavit states that the student will file for permanent residency at the earliest…

  5. 31 CFR 309.2 - Description of Treasury bills (General).

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Description of Treasury bills (General). 309.2 Section 309.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT ISSUE AND SALE OF...

  6. Active pollinator choice by Heliconia 'fits the bill'.

    Science.gov (United States)

    Bronstein, Judith L; Richman, Sarah K

    2015-07-01

    A new study documents that a tropical plant only reproduces when pollen has been deposited by a visitor capable of extracting nectar from its deep flowers. Large, long-billed hummingbirds generally carry greater quantities of, and more genetically diverse, pollen. Thus, plants can exert more active partner choice than previously considered possible.

  7. Size & Flow: Adult Education Issues in the Senate Immigration Bill

    Science.gov (United States)

    Murphy, Garrett; Spangenberg, Gail

    2014-01-01

    In this essay Garrett Murphy and Gail Spangenberg report on the need for understanding better than in the past, the number of undocumented immigrants likely to need adult education services under provisions of Senate Immigration Bill S.744. The essay looks at why the issues of "size and flow" are important for planners, providers, and…

  8. The Interpretation of Dreams: Ladson-Billings, Freud, and Derrida

    Science.gov (United States)

    Greenwalt, Kyle

    2010-01-01

    This study provides a critical and close reading of "The Dreamkeepers" (1994), by Gloria Ladson-Billings. The paper focuses primarily on the gendered nature of "being a teacher" and "being a student" as revealed in the dreamkeeper text, while maintaining its engagement with race and culture as it is manifested in the United States context. It…

  9. GI Bill Offers Military Children Relief from College Costs

    Science.gov (United States)

    Sander, Libby

    2013-01-01

    As a new GI Bill moved through Congress in 2008, a handful of influential politicians grew concerned. Would such a generous education program trigger an exodus of service members during two wars? At the Pentagon's urging, the lawmakers proposed a fix: Give troops the option to transfer their benefits to a child or spouse. That policy quickly…

  10. Empty Promise: Black American Veterans and the New GI Bill

    Science.gov (United States)

    Ottley, Alford H.

    2014-01-01

    The 2008 GI Bill offers college funds for veterans. Yet Black male vets are not taking advantage of these benefits. This chapter examines personal and societal problems that hinder access to higher education for Black vets, and suggests some ways adult educators can advocate for these young men.

  11. Bill Gates : Miljardärist nohik / Martin Hanson

    Index Scriptorium Estoniae

    Hanson, Martin, 1984-

    2008-01-01

    Bill Gates loobub Microsofti juhi kohast ning jätkab vaid nõustajana. Vt. samas: Elulugu; Tasub teada; Miljardär, kes hoiab oma eraelu kiivalt saladuses. Kommenteerivad Microsoft Eesti esinduse juht Rain Laane ja IBM Eesti juht Valdo Randpere

  12. The "Ever Green" Interpretations of the "Library Bill of Rights"

    Science.gov (United States)

    Adams, Helen R.

    2010-01-01

    The American Library Association's (ALA) "Library Bill of Rights" is important to school librarians because it provides the philosophical structure for intellectual freedom in school libraries and asserts the rights of minors. It states: "A person's right to use a library should not be denied or abridged because of origin, age,…

  13. Bill and Melinda Gates Pledge $1-Billion for Minority Scholarships.

    Science.gov (United States)

    Monaghan, Peter; Lederman, Douglas; van der Werf, Martin; Pulley, John

    1999-01-01

    Reports on a $1 billion dollar grant from Bill and Melinda Gates to send 20,000 low-income minority students to college. The Gates Millenium Scholars Program will require students to demonstrate financial need and maintain a 3.0 grade point average in college. A list of the largest private gifts to higher education since 1967 is also provided. (DB)

  14. Creating a standardized and simplified cutting bill using group technology

    Science.gov (United States)

    Urs Buehlmann; Janice K. Wiedenbeck; R., Jr. Noble; D. Earl Kline

    2008-01-01

    From an analytical viewpoint, the relationship between rough mill cutting bill part requirements and lumber yield is highly complex. Part requirements can have almost any length, width, and quantity distribution within the boundaries set by physical limitations, such as maximum length and width of parts. This complexity makes it difficult to understand the specific...

  15. an assessment of billing electricity consumers via analogue meters ...

    African Journals Online (AJOL)

    DR. AMINU

    Questionnaire survey was used to collect data from the consumers, frequency counts and percentages were used to analyze the generated data. The result of the .... research. Table 3: Consumer billed and consumer Payments response from January to June 2008 ... The researcher will discuss: 1). the design of the survey ...

  16. Senate health bill lacks 50 votes needed to proceed

    Directory of Open Access Journals (Sweden)

    Moore NS

    2017-07-01

    Full Text Available No abstract available. Article truncated at 150 words. Yesterday (7/17, two additional Senators – Sen. Roberts (R-KS and Sen. Lee (R-NE joined Senators Paul (R-KY and Collins (R-ME in announcing their intention to vote “no” on the motion to proceed on considering the Senate ACA repeal and replace legislation – effectively blocking Senate consideration of the current Senate Republican health care bill. Senators Paul, Lee and Roberts opposed the bill for not going far enough, while Senator Collins expressed her concern the bill goes too far. With the 4 publicly announced NO votes – Senator Majority Leader Mitch McConnell does not have the 50 votes needed to begin debate on the bill, let alone assure final passage. Speculation now turns to what happens next. President Trump has tweeted his preference to let Obamacare fail as a way to force Democrats to negotiate new legislation. Senator McConnell has suggested a series of symbolic votes on full repeal with multi-year delay to work …

  17. Mental Health Care Bill 2013: The Place of Electroconvulsive Therapy

    Directory of Open Access Journals (Sweden)

    Bangalore N Gangadhar

    2015-01-01

    Full Text Available Electroconvulsive therapy (ECT is one of the oldest medical treatments in psychiatry. The practice has evolved over the years, and the indications have become better defined now. Notwithstanding these, it remains a highly regulated and scrutinized practice. Indian laws specifically related to ECT do not exist till date though this would change if the purported mental health care bill 2013 becomes the law of the land. ECT gets both direct and indirect mention at various places in the bill with far-reaching consequences impacting patients, families, and the professionals. Ban on “ECT as an emergency treatment option” and on “unmodified ECT” is being sought. In addition, ECT in minors is slated to come under stricter regulation. ECT could also get implicated under the “advance directives” provisions of the bill. This naturally has triggered vociferous debates throughout the country between the supporters as well as detractors of ECT. A number of ethical, professional, logistic, and clinical concerns are being discussed. In this background, we attempt to critically evaluate the bill with regard to ECT in the background of the existent scientific and legal literature. We provide possible future directions with regard to ECT practice and its regulation.

  18. Freedom of Movement (Common Travel Area) (Travel Documentation) Bill 2014

    DEFF Research Database (Denmark)

    Butler, Graham; Hunt, Brian; Flanagan, Terence

    2014-01-01

    Private Members' Bill (legislation) introduced in Dáil Éireann (House of Deputies), Houses of the Oireachtas (Irish Parliament). An Act to reinforce the Common Travel Area by providing for passport-free travel for persons who are entitled to travel within the Common Travel Area without a passport...

  19. Roost site selection by ring-billed and herring gulls

    Science.gov (United States)

    Clark, Daniel E.; Destefano, Stephen; MacKenzie, Kenneth G.; Koenen, Kiana K. G.; Whitney, Jillian J.

    2016-01-01

    Gulls (Larus spp.) commonly roost in large numbers on inland and coastal waters, yet there is little information on how or where gulls choose sites for roosting. Roost site selection can lead to water quality degradation or aviation hazards when roosts are formed on water supply reservoirs or are close to airports. Harassment programs are frequently initiated to move or relocate roosting gulls but often have mixed results because gulls are reluctant to leave or keep returning. As such, knowledge of gull roost site selection and roosting ecology has applied and ecological importance. We used satellite telemetry and an information-theoretic approach to model seasonal roost selection of ring-billed (L. delawarensis) and herring gulls (L. argentatus) in Massachusetts, USA. Our results indicated that ring-billed gulls preferred freshwater roosts and will use a variety of rivers, lakes, and reservoirs. Herring gulls regularly roosted on fresh water but used salt water roosts more often than ring-billed gulls and also roosted on a variety of land habitats. Roost modeling showed that herring and ring-billed gulls selected inland fresh water roosts based on size of the water body and proximity to their last daytime location; they selected the largest roost closest to where they ended the day. Management strategies to reduce or eliminate roosting gulls could identify and try to eliminate other habitat variables (e.g., close-by foraging sites) that are attracting gulls before attempting to relocate or redistribute (e.g., through hazing programs) roosting birds.

  20. 47 CFR 36.380 - Other billing and collecting expense.

    Science.gov (United States)

    2010-10-01

    ... statistical work, controlling record work and the preparation of revenue reports. (b) Local exchange carriers..., study areas subject to price cap regulation, pursuant to § 61.41 of this chapter, shall assign the balance of Account 6620-Services to the Other billing and collecting expense classification based on...

  1. 12 CFR 226.13 - Billing error resolution. 27

    Science.gov (United States)

    2010-01-01

    ..., 12 CFR 205.11 governing error resolution rather than those of paragraphs (a), (b), (c), (e), (f), and... account, the creditor shall comply with the requirements of Regulation E, 12 CFR 205.11 governing error... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Billing error resolution. 27 226.13 Section...

  2. Bill Gates : Miljardärist nohik / Martin Hanson

    Index Scriptorium Estoniae

    Hanson, Martin, 1984-

    2008-01-01

    Bill Gates loobub Microsofti juhi kohast ning jätkab vaid nõustajana. Vt. samas: Elulugu; Tasub teada; Miljardär, kes hoiab oma eraelu kiivalt saladuses. Kommenteerivad Microsoft Eesti esinduse juht Rain Laane ja IBM Eesti juht Valdo Randpere

  3. US Congress considers bill to relieve helium shortage

    Science.gov (United States)

    Gwynne, Peter

    2013-04-01

    A bill to alleviate the threat of a significant shortage of helium was set to be debated in the US House of Representatives as Physics World went to press with the House's Natural Resources Committee putting the finished touches to the motion.

  4. The Interpretation of Dreams: Ladson-Billings, Freud, and Derrida

    Science.gov (United States)

    Greenwalt, Kyle

    2010-01-01

    This study provides a critical and close reading of "The Dreamkeepers" (1994), by Gloria Ladson-Billings. The paper focuses primarily on the gendered nature of "being a teacher" and "being a student" as revealed in the dreamkeeper text, while maintaining its engagement with race and culture as it is manifested in the United States context. It…

  5. Healing and the Mind with Bill Moyers. Resource Materials.

    Science.gov (United States)

    Grippo, Lois; Kelso, Richard

    This high school resource package for the public television series "Healing and the Mind with Bill Moyers" includes: (1) a teacher's guide that provides complete lesson plans for each program in the series; (2) a glossary that features definitions of the terms used in the series; (3) a bibliography containing books of interest to both…

  6. The Language of Life with Bill Moyers: Teacher's Guide.

    Science.gov (United States)

    Reisman, David, Ed.

    Designed to be used with the 8-part public television series "The Language of Life with Bill Moyers," this guide serves as a learning resource for the study of contemporary American poetry. The guide presents 18 full-size cards that feature the work of each of the poets in the series; selected poems that appear in the series; questions…

  7. The "Ever Green" Interpretations of the "Library Bill of Rights"

    Science.gov (United States)

    Adams, Helen R.

    2010-01-01

    The American Library Association's (ALA) "Library Bill of Rights" is important to school librarians because it provides the philosophical structure for intellectual freedom in school libraries and asserts the rights of minors. It states: "A person's right to use a library should not be denied or abridged because of origin, age,…

  8. Politicizing Sociology through a Bill of Rights Learning Module

    Science.gov (United States)

    Sweet, Stephen

    2009-01-01

    Writers in this journal have presented a number of strategies that sociology teachers can use to facilitate the expression--and serious analysis--of unpopular opinions. This article contributes to this dialog by illustrating the application of a Bill of Rights learning module. In this module, students are expected to create a document that…

  9. The Bill of Rights in Action, 2002-2003.

    Science.gov (United States)

    Martz, Carlton

    2003-01-01

    This document includes the following issues of this journal: volume 18, number 3, Summer 2002; volume 18, number 4, Fall 2002; volume 19, number 2, Spring 2003; and volume 19, number 3, Summer 2003. The summer 2002 issue of "The Bill of Rights in Action" views problems related to victims of war. It focuses on the internment of Japanese…

  10. Freedom of Movement (Common Travel Area) (Travel Documentation) Bill 2014

    DEFF Research Database (Denmark)

    Butler, Graham; Hunt, Brian; Flanagan, Terence

    2014-01-01

    Private Members' Bill (legislation) introduced in Dáil Éireann (House of Deputies), Houses of the Oireachtas (Irish Parliament). An Act to reinforce the Common Travel Area by providing for passport-free travel for persons who are entitled to travel within the Common Travel Area without a passport...

  11. Cirugía Neonatal en la primera semana de vida. Hospital Académico "Nelson Mándela". Mthatha .Sudáfrica

    OpenAIRE

    Arturo L. Delgado Delgado

    2009-01-01

    Se plantea que el conocimiento y entendimiento mejor de la fisiología neonatal y los avances en la tecnología, han mejorado los resultados de la cirugía neonatal; sin embargo en África Subsahariana, ésta enfrenta muchos problemas. Para conocer la calidad de la atención que reciben los neonatos de ese grupo en el centro Hospital Académico "Nelson Mándela", es que se decidió estudiar todos aquellos a quienes se les realizó una cirugía mayor en su primera semana de vida: mayo 2004 a mayo 2006. S...

  12. Desbotone en diferentes estadios de desarrollo del botón floral en clavel estándar (dianthus caryophyllus l.) var. nelson

    OpenAIRE

    Arévalo, Gabriel Alexander; Ibarra, Daniel Alberto; Flórez, Víctor Julio

    2010-01-01

    Los mayores costos de producción del clavel estándar se asocian con la mano de obra que se utiliza en las labores del cultivo; el desbotone es una de las actividades que demanda mayor uso de mano de obra y tiempo. El objetivo del estudio fue determinar el efecto del desbotone en diferentes estadios de desarrollo del botón principal, sobre la producción y calidad en poscosecha del clavel estándar variedad Nelson en el primer pico de cosecha. Se evaluaron los estadios conocidos popularmen...

  13. p-hacking by post hoc selection with multiple opportunities: Detectability by skewness test?: Comment on Simonsohn, Nelson, and Simmons (2014).

    Science.gov (United States)

    Ulrich, Rolf; Miller, Jeff

    2015-12-01

    Simonsohn, Nelson, and Simmons (2014) have suggested a novel test to detect p-hacking in research, that is, when researchers report excessive rates of "significant effects" that are truly false positives. Although this test is very useful for identifying true effects in some cases, it fails to identify false positives in several situations when researchers conduct multiple statistical tests (e.g., reporting the most significant result). In these cases, p-curves are right-skewed, thereby mimicking the existence of real effects even if no effect is actually present.

  14. [Nelson Rockefeller and the activities of the American International Association for Economic and Social Development: the debate concerning mission and imperialism in Brazil, 1946-1961].

    Science.gov (United States)

    Silva, Claiton Marcio da

    2013-10-01

    The article analyzes the bibliography on Nelson Rockefeller and the activities of the American International Association for Economic and Social Development in Brazil. It describes optimistic interpretations of Rockefeller's and the association's work, as well as the nationalist stream of thought, which characterized him as one of the chief representatives of U.S. imperialism, both as a political representative in the 1960s and as the mind behind endeavors of interest to the private sector. It is shown that at the individual and agency levels alike, these initiatives involved direct ties to the local elites, who influenced the reshaping and operationalization of technical cooperation projects.

  15. Senate working on reauthorization of water resources development bill

    Science.gov (United States)

    Showstack, Randy

    2012-10-01

    Although the details are not even written for forthcoming legislation to reauthorize the U.S. federal Water Resources Development Act (WRDA), three broad themes emerged during a 20 September hearing by the U.S. Senate Committee on Environment and Public Works (EPW). First, passage of the WRDA bill, which would authorize water projects around the country, already appears to have bipartisan support, as well as support from conservation, industry, and labor groups. WRDA was last reauthorized in 2007 when the Senate voted 79-14 in broad bipartisan support to override President George W. Bush's veto of the $23 billion bill. Second, although the U.S. Army Corps of Engineers—which manages, operates, and maintains a vast water resources infrastructure including more than 600 dams, 926 harbors, and 12,000 miles of commercial inland navigation channels—received some praise for its projects, it was also criticized as being a bureaucracy in need of repair. Third, WRDA legislation is operating under different ground rules than in the past. EPW committee chair Barbara Boxer (D-Calif.) said that she has been working with Republicans on WRDA legislation and that she hopes to move forward with a bill later this year—possibly bringing it up for a markup during Congress's lame duck session following the national election in November. She said that would be a way to set a marker for leadership on both sides of the congressional aisle to move forward with the bill. Boxer said she would "get my dream bill in place" and then provide it to committee ranking member James Inhofe (R-Okla.) and other Republicans for their comments.

  16. Food insecurity among students living with HIV: Strengthening safety nets at the Nelson Mandela Metropolitan University, South Africa.

    Science.gov (United States)

    Steenkamp, L; Goosen, A; Venter, D; Beeforth, M

    2016-12-01

    The HIV prevalence in South Africa among students at higher education institutions (HEIs) in 2008 was reported to be 3.4%, with the highest HIV prevalence found in the Eastern Cape Province. Students at these facilities are also increasingly affected by socio-economic constraints that may impact on food security. Little is known about the impact of food insecurity on HIV-infected students in HEIs in South Africa. The purpose of this paper is to describe food insecurity and the nutritional status among HIV-infected students on the Nelson Mandela Metropolitan University campuses in South Africa, as well as current initiatives to strengthen the safety nets for food-insecure students. This descriptive, cross-sectional survey was conducted among a convenience sample of known HIV-infected, registered students (n = 63), older than 18 years of age and managed as part of the Campus Health Service antiretroviral therapy (ART) programme. Ethical approval for the study was obtained from the Research Ethics Committee (NMMU) and participants were included in the sample after providing written, informed consent. Findings indicate that food insecurity was common with more than 60% of the sample reporting food insecurity at the household level during the previous month. Of the sample, 51% were classified as being either overweight or obese. Although food insecurity did not contribute to weight loss in our sample, food-insecure students were more likely to consume inadequate amounts of vitamins and minerals, especially antioxidants that are important in supporting the immune system. Food insecurity has been identified as affecting the majority of HIV-infected students in this study, especially regarding their difficulty in accessing nutritious foods. As overweight and obesity also seem to threaten the health and future well-being of the students, appropriate management of the overweight individuals and those with obesity should be instituted in order to prevent the development

  17. Food insecurity among students living with HIV: Strengthening safety nets at the Nelson Mandela Metropolitan University, South Africa

    Directory of Open Access Journals (Sweden)

    L. Steenkamp

    2016-01-01

    Full Text Available The HIV prevalence in South Africa among students at higher education institutions (HEIs in 2008 was reported to be 3.4%, with the highest HIV prevalence found in the Eastern Cape Province. Students at these facilities are also increasingly affected by socio-economic constraints that may impact on food security. Little is known about the impact of food insecurity on HIV-infected students in HEIs in South Africa. The purpose of this paper is to describe food insecurity and the nutritional status among HIV-infected students on the Nelson Mandela Metropolitan University campuses in South Africa, as well as current initiatives to strengthen the safety nets for food-insecure students. This descriptive, cross-sectional survey was conducted among a convenience sample of known HIV-infected, registered students (n = 63, older than 18 years of age and managed as part of the Campus Health Service antiretroviral therapy (ART programme. Ethical approval for the study was obtained from the Research Ethics Committee (NMMU and participants were included in the sample after providing written, informed consent. Findings indicate that food insecurity was common with more than 60% of the sample reporting food insecurity at the household level during the previous month. Of the sample, 51% were classified as being either overweight or obese. Although food insecurity did not contribute to weight loss in our sample, food-insecure students were more likely to consume inadequate amounts of vitamins and minerals, especially antioxidants that are important in supporting the immune system. Food insecurity has been identified as affecting the majority of HIV-infected students in this study, especially regarding their difficulty in accessing nutritious foods. As overweight and obesity also seem to threaten the health and future well-being of the students, appropriate management of the overweight individuals and those with obesity should be instituted in order to prevent

  18. Inhibition of herpes simplex virus type 1 replication by adeno-associated virus rep proteins depends on their combined DNA-binding and ATPase/helicase activities.

    Science.gov (United States)

    Glauser, Daniel L; Seyffert, Michael; Strasser, Regina; Franchini, Marco; Laimbacher, Andrea S; Dresch, Christiane; de Oliveira, Anna Paula; Vogel, Rebecca; Büning, Hildegard; Salvetti, Anna; Ackermann, Mathias; Fraefel, Cornel

    2010-04-01

    Adeno-associated virus (AAV) has previously been shown to inhibit the replication of its helper virus herpes simplex virus type 1 (HSV-1), and the inhibitory activity has been attributed to the expression of the AAV Rep proteins. In the present study, we assessed the Rep activities required for inhibition of HSV-1 replication using a panel of wild-type and mutant Rep proteins lacking defined domains and activities. We found that the inhibition of HSV-1 replication required Rep DNA-binding and ATPase/helicase activities but not endonuclease activity. The Rep activities required for inhibition of HSV-1 replication precisely coincided with the activities that were responsible for induction of cellular DNA damage and apoptosis, suggesting that these three processes are closely linked. Notably, the presence of Rep induced the hyperphosphorylation of a DNA damage marker, replication protein A (RPA), which has been reported not to be normally hyperphosphorylated during HSV-1 infection and to be sequestered away from HSV-1 replication compartments during infection. Finally, we demonstrate that the execution of apoptosis is not required for inhibition of HSV-1 replication and that the hyperphosphorylation of RPA per se is not inhibitory for HSV-1 replication, suggesting that these two processes are not directly responsible for the inhibition of HSV-1 replication by Rep.

  19. Treatment with lenalidomide (Revlimid®), cyclophosphamide (Endoxan®) and prednisone (REP) in relapsed/refractory multiple myeloma patients: results of a single centre retrospective study.

    Science.gov (United States)

    Zelis, N; Devos, T; Dierickx, D; Janssens, A; Raddoux, J; Verhoef, G; Delforge, M

    2014-04-01

    Lenalidomide (Revlimid®) combined with intermittent dexamethasone (the RD regimen) is one of the current standards for treatment of patients with relapsed/refractory multiple myeloma (MM). However, since the disease in the majority of patients will become resistant to RD, or treatment with RD needs to be discontinued due to side effects, we evaluated the combination lenalidomide, low-dose oral cyclophosphamide, with prednisone (REP) in patients with relapsed/refractory MM previously exposed to RD. For this purpose, we performed a single centre retrospective study of the efficacy of REP in 19 patients with relapsed/refractory MM. Overall response rate (partial response or better) with REP was 68% compared with 83% with RD, but with a shorter time to response with the triplet REP. Time to progression after REP was 6 months. Overall the REP regimen was better tolerated compared to RD. We conclude that the REP regimen is an effective treatment regimen for patients with relapsed/refractory MM with good tolerance, warranting further exploration in prospective randomized trials.

  20. Stylistic Analysis on "Bill's Little Girl":Lexical Features%Stylistic Analysis on "Bill's Little Girl": Lexical Features

    Institute of Scientific and Technical Information of China (English)

    曲雯

    2011-01-01

    "Bill's Little Girl " is a prose.This article analysis's its stylistic features of language in the aspects of lexical.While analysis,we can further appreciate its plain and simple language,its natural and fluent manner of writing and its complete discourse,meanwhile we can deeply understand that love is great,father's love is great.

  1. Kill Bill! Ugandan human rights organizations' attempts to influence the media's coverage of the Anti-Homosexuality Bill.

    Science.gov (United States)

    Strand, Cecilia

    2011-09-01

    The Ugandan Anti-Homosexuality Bill of October 2009 caused an international outcry and sparked intense debate in the local and international media. Particularly contentious was its proposal to impose the death penalty for acts of 'aggravated homosexuality'. Through a quantitative content analysis of 176 items from two main daily newspapers, the government-owned New Vision and the privately-owned Daily Monitor, over the period October 2009-June 2010, combined with qualitative interviews with human rights defenders in Uganda, this study explores attempts made by local human rights advocates to influence the media's coverage of the Bill and the extent to which these attempts were successful. The study finds that while there are significant differences between the frequency of reporting on the Bill in the two newspapers, both papers devoted little editorial space to the public health and human rights concerns put forward by local human rights organizations. Despite Uganda's recent and often lauded history of openly addressing HIV/AIDS, human right organizations' attempts to highlight the Bill's potentially adverse effects on the country's ability to tackle the epidemic effectively were only partially successful and, interestingly, awarded much less attention than the potential human rights implications of the proposed change in legislation.

  2. Ways of implementation of fatf recommendations on combating criminal incomes at bills market

    Directory of Open Access Journals (Sweden)

    Анатолій Іванович Гулей

    2015-05-01

    Full Text Available In this article the measures directed on counteraction to laundering of criminal incomes are considered about the financial transaction with using bills of exchange and promissory notes. A study and analysis of the development process of bills of exchange and promissory notes in different countries of the world, the nature of bills as payment document, securities, commercial and bank credit, and process of immobilization of bills. Also, the problems of the legal framework relating to bill circulation in Ukraine are investigated and some recommendations for reduce the risks of bill circulation are given

  3. Fatigue Level Estimation of Bill Based on Acoustic Signal Feature by Supervised SOM

    Science.gov (United States)

    Teranishi, Masaru; Omatu, Sigeru; Kosaka, Toshihisa

    Fatigued bills have harmful influence on daily operation of Automated Teller Machine(ATM). To make the fatigued bills classification more efficient, development of an automatic fatigued bill classification method is desired. We propose a new method to estimate bending rigidity of bill from acoustic signal feature of banking machines. The estimated bending rigidities are used as continuous fatigue level for classification of fatigued bill. By using the supervised Self-Organizing Map(supervised SOM), we estimate the bending rigidity from only the acoustic energy pattern effectively. The experimental result with real bill samples shows the effectiveness of the proposed method.

  4. El montaje de la transición argentina. Un análisis de los films La República perdida, La República perdida II y Evita, quien quiera oír que oiga

    Directory of Open Access Journals (Sweden)

    Paola Judith Margulis

    2012-01-01

    Full Text Available El presente artículo se propone reconstruir una zona de la historia del documental argentino a partir del abordaje de tres films que tuvieron un alto impacto en Argentina hacia la transición democrática: La República perdida (Miguel Pérez, 1983, su secuela La República perdida II (Miguel Pérez, 1986 y Evita, quien quiera oír que oiga (Eduardo Mignogna, 1984. Dada la importancia de estos films -tanto en términos políticos como de impacto en el público-, intentaremos situarlos en contexto y analizar algunos aspectos inherentes a su lógica fílmica.

  5. Lecturas de un sueño. (Sobre la República literaria de Saavedra Fajardo

    Directory of Open Access Journals (Sweden)

    Rodríguez, Juan Carlos

    2013-12-01

    Full Text Available The author of the República Literaria, a diplomatic voyager from the 17th Century, dreams of a city of paper: to read a city as if it were a book and to read a book as if it were a journey throughout literary history. Is it possible? On this journey across all of written culture that Saavedra describes, where the inhabitants of the city are authors of ‘literary’ texts and the arts live together with the sciences and the muses, the author analyses with subtle irony the present and the tradition of everything that surrounds the production of all that is written. With the classic resource of the ‘Dream’ he shows an incredibly clear panorama where we can recognize the beginnings of capitalism, in which books have gone from being considered repositories of wisdom and common sense, to becoming mere marketplace objects.El autor de la República Literaria, un diplomático viajero del siglo XVII, sueña una ciudad de papel: leer una ciudad como si fuera un libro y leer un libro como si fuera un viaje a través de la historia literaria. ¿Es posible? En este recorrido por toda la cultura escrita que traza Saavedra, donde los habitantes de la ciudad son los autores de los textos «literarios» y las artes conviven con las ciencias y las musas, el autor desmenuza con finísima ironía la actualidad y la tradición de todo lo que rodea a la producción de lo escrito. Con el clásico recurso del «Sueño» muestra un panorama increíblemente nítido donde podemos reconocer los inicios del capitalismo en el que los libros han pasado de ser considerados como un depósito de sabiduría y cordura a tener carácter de mero objeto de mercado.

  6. Differences in bill form of the oystercatcher haematopus ostralegus; a dynamic adaptation to specific foraging techniques

    Science.gov (United States)

    Swennen, C.; De Bruijn, L. L. M.; Duiven, P.; Leopold, M. F.; Marteijn, E. C. L.

    In wintering European oystercatchers 3 bill types: pointed, chisel-shaped, and blunt were found as well as their intermediates. The distribution of the different bill types varied widely in both time and space. Pointed bills had a larger mean length than both chisel-shaped and blunt bills, and occurred more often in young birds than in adults, and more often in females than in males. On an average, females had longer bills than males. In oystercatchers in the Wadden Sea area bill length was found to increase with age, but in the Delta area no increase was found. In semi-natural cage experiments each bill type proved to be most suitable for a specific manner of localization and handling of prey. Bills of individual oystercatchers were shown to change shape when the bird was forced to change its feeding method. A change in method accompanied by a gradual change in bill form only caused a temporary loss of feeding efficiency. It is concluded that differences in bill length influence prey choice and feeding method and hence induce different bill forms. Age- and sex-dependent differences in bill length and form, together with the ability of the individual to adapt bill form and feeding behaviour, enable the oystercatcher to lessen interspecific competition and to respond to changing environmental conditions.

  7. Alternativas de modificación del método de somogyi-nelson para la determinación de azúcares reductores a partir de sus posibilidades químicas

    OpenAIRE

    González Blair, Gloria Helena; Castellanos Domínguez, Óscar Fernando

    2010-01-01

    En el presente artículo se plantea modificar el método de Somogyi-Nelson para la determinación de azúcares reductores, considerando que el arsenato de sodio, uno de sus constituyentes, es una sustancia tóxica tendiente a desparecer del mercado. Se explican los principios químicos que utiliza el método de Somogyi - Nelson para la determinación de azúcares reductores, tomando como referencia los protocolos propuestos por Hawk et al. (1954), Collmer et al. (1988), Castellanos (1995) y el Departa...

  8. A Critique of the Unemployment Insurance Amendment Bill, 2015

    OpenAIRE

    Marius Olivier; Avinash Govindjee

    2015-01-01

    The contribution critically reflects on the proposed amendments to the Unemployment Insurance Act Act 63 of 2001 (the UIA / the Act), introduced via the provisions of the Unemployment Insurance Amendment Bill of 2015 (B25-2015). Several shortcomings and deficiencies are addressed and improvements introduced by the proposed amending legislation, including the extension of coverage to a wider range of beneficiaries, the extension of the period of benefits (to a maximum of 365 days), the increas...

  9. National Survey of Patients’ Bill of Rights Statutes

    OpenAIRE

    Paasche-Orlow, Michael K; Jacob, Dan M.; Hochhauser, Mark; Parker, Ruth M.

    2009-01-01

    BACKGROUND Despite vigorous national debate between 1999–2001 the federal patients’ bill of rights (PBOR) was not enacted. However, states have enacted legislation and the Joint Commission defined an accreditation standard to present patients with their rights. Because such initiatives can be undermined by overly complex language, we surveyed the readability of hospital PBOR documents as well as texts mandated by state law. METHODS State Web sites and codes were searched to identify PBOR stat...

  10. Nurses' knowledge and performance of the patients' bill of rights.

    Science.gov (United States)

    Sheikhtaheri, Abbas; Jabali, Monireh Sadeqi; Dehaghi, Zahra Hashemi

    2016-12-01

    Observance of the patients' bill of rights is one of the main features of moral codes in hospitals. In this regard, nurses bear great responsibility because they spend a long time with patients. Therefore, the continuous evaluation of the nurses' performance and assessing their knowledge about the patients' bill of rights are a need. We aimed to determine the nurses' awareness of the patients' rights and measure their performance in this regard. Research design and participants: This cross-sectional study was carried out in 2013. To measure the nurses' knowledge and performance, 250 nurses and 300 patients were surveyed. The participants were selected randomly from five teaching hospitals in Tehran, Iran. Two questionnaires, one for nurses (17 questions) and the other for patients (11 questions), were applied. The data were analyzed in SPSS software using descriptive and inferential statistics. Ethical consideration: The research protocol was submitted and approved by the research and ethics committees of the participating hospitals. Additionally, the consent of all of the participants was obtained before the study. The mean score of the nurses' knowledge regarding the patients' rights was acceptable (69.85 ± 11.7 of 85). Furthermore, the mean score of nurses' performance in observing the patients' rights was relatively acceptable (11.2 ± 4.6 of 22). More experienced and educated nurses had higher knowledge regarding the patients' rights, and patients with higher education level or experience of being hospitalized were less satisfied with the nurses' performance. Nurses' knowledge of the patients' bill of rights was acceptable; however, observance of the patients' rights was not. It seems that notification of the patients' bill of rights has increased the nurses' awareness of the patients' rights, although improvement of the nurses' performance needs more extensive measures.

  11. Pleonexía: el centro ausente de La República de Platón

    OpenAIRE

    Carrasco, Nemrod

    2008-01-01

    La pleonexía es una categoría platónica más complicada de lo que puede parecer. Tradicionalmente asociada a las posiciones de Calicles y Trasímaco, lo primero que nos indica La república es que la pleonexía no es únicamente el motor constitutivo de toda ciudad, sino el punto de referencia decisivo de la concepción platónica de la justicia. Es ahí donde radica la paradoja del tránsito de la ciudad sana de Sócrates a la ciudad enferma de Glaucón: lejos de rep...

  12. Liberalismo, iluminismo y romanticismo: el problema de la libertad en dos novelas de la República Restaurada

    Directory of Open Access Journals (Sweden)

    Verónica Hernández Landa Valencia

    2016-07-01

    Full Text Available El artículo propone una reflexión en torno a la forma como influyen tres corrientes de pensamiento, el liberalismo, el iluminismo y el romanticismo, en la representación del problema de la libertad en dos novelas históricas publicadas en la República Restaurada: Monja y casada, virgen y mártir, de Vicente Riva Palacio, y El pecado del siglo, de José Tomás de Cuéllar. Se busca mostrar que dichas corrientes se entrecruzan en un solo texto, que ello contribuye a la conformación de un concepto de libertad restringida y que la forma específica que adquiere ese concepto se explica a partir de la postura ideológica y política de los autores en el contexto de la República Restaurada.

  13. 150 años despues: Constitución de la república de Tunja

    Directory of Open Access Journals (Sweden)

    José Hurtado García

    1961-12-01

    Full Text Available En Tunja perduran abiertos los corazones y los zaguanes. La Villa noble de Suárez Rendón, embelesada en el canto de la Madre Castillo y de don Juan de Castellanos, amaneció en la República con el sacrificio de sus hijos y con sus ideas proceras. Precisamente en este mes de diciembre de 1961 -el nueve- se cumplen los ciento cincuenta años de la expedición de su Constitución, cuyo título definido reza: " Constitución de la República de Tunja sancionada en plena Asamblea de los Representantes de toda la Provincia, en sesiones continuas desde el 21 de noviembre hasta el 9 de diciembre de 1811. Año Segundo de la Transformación Política del Nuevo Reyno de Granada".

  14. A “Primeira República”: os preceitos liberais e a práxis oligárquica

    Directory of Open Access Journals (Sweden)

    Flávia Liziane Gonzáles Bandeira

    2009-04-01

    Full Text Available O presente artigo visa a analisar o processo de mudança de regime político no Brasil, no final do século XIX – o advento da República. As fontes utilizadas da análise são um fragmento da primeira Constituição republicana e os programas dos partidos Republicano Federal e Republicano Conservador. Visou-se a buscar os limites entre o discurso encontrado nesses documentos e a prática política realizada no Brasil da República Velha. Para melhor extrair o teor do documento foi utilizada a técnica metodológica de análise de conteúdo quantitativa, nomeando unidades referenciais mais incidentes nos respectivos textos, seguida da análise qualitativa aplicada a estas.

  15. Endine FBI agent õpetab eestlasi allilma imbuma / Bill Moschella ; interv. Rasmus Kagge

    Index Scriptorium Estoniae

    Moschella, Bill

    2004-01-01

    Ameerika Föderaalse Juurdlusbüroo (FBI) endine eriagent Bill Moschella hakkab treenima siinseid kriminaalpolitseinikke, õpetab, kuidas paremini tööd organiseerida ja kurjategijate paljastamiseks varioperatsioone korraldada. Lisa: Bill Moschella

  16. Endine FBI agent õpetab eestlasi allilma imbuma / Bill Moschella ; interv. Rasmus Kagge

    Index Scriptorium Estoniae

    Moschella, Bill

    2004-01-01

    Ameerika Föderaalse Juurdlusbüroo (FBI) endine eriagent Bill Moschella hakkab treenima siinseid kriminaalpolitseinikke, õpetab, kuidas paremini tööd organiseerida ja kurjategijate paljastamiseks varioperatsioone korraldada. Lisa: Bill Moschella

  17. Group Billing for University Residence Hall Damages: A Common but Questionable Practice.

    Science.gov (United States)

    Richmond, Douglas R.

    1989-01-01

    University residence hall administrators employ a variety of strategies, including group billing, to combat vandalism. Reviews theoretical and practical bases for group billing; examines potential challenges to the practice; and offers recommendations for residence administrators and university counsel. (MLF)

  18. Organizational Contexts and Texts: The Redesign of the Midwest Bell Telephone Bill.

    Science.gov (United States)

    Keller-Cohen, Deborah

    1987-01-01

    Offers a retrospective view of organizational factors affecting the redesign of the Midwest Bell Telephone Bill. Shows how financial considerations, organizational time frame, and employee training and experience influenced the bill's development process. (MM)

  19. Preventive resin restorations: practice and billing patterns of pediatric dentists.

    Science.gov (United States)

    Savage, Bryan; McWhorter, Alton G; Kerins, Carolyn A; Seale, N Sue

    2009-01-01

    The purpose of this study was to determine practice patterns of pediatric dentists for preventive resin restorations (PRRs) and if they believe a code should be added to the American Dental Association's current dental terminology (CDT) for the PRR. A 16-question survey sent to 475 pediatric dentists randomly selected from the American Academy of Pediatric Dentistry database, addressed demographics, treatment planning, techniques in preparation and restoration, billing practices, and perceptions about the need for a CDT code for PRRs. Two hundred thirty-eight (50%) surveys were returned, revealing that 72% of respondents perform PRRs and 64% feel that a PRR code should be added to the CDT Fifty-two percent believe not having a CDT code could cause dentists to perform more invasive dentistry to comply with billing requirements that Class I restorations be in dentin. PRRs are commonly treatment planned for deep pits and fissures with questionable decoy not entering dentin. Up to 50% of respondents could be erroneously billing for PRRs. Most pediatric dentists perform preventive resin restorations in their office and believe that a code for the procedure needs to be added to the current dental terminology.

  20. O sistema oligárquico representativo da Primeira República

    Directory of Open Access Journals (Sweden)

    Wanderley Guilherme dos Santos

    2013-03-01

    Full Text Available Entre les absolutismes des XVIIe et XVIIIe siècles, d'une part, et les variantes démocratiques repérées après la Seconde Guerre Mondiale, d'autre part, demeure un brouillard conceptuel gênant la compréhension de l'histoire politico-institutionnelle de cette période. L'oligarchie, traitée soit comme germe de démocratie soit comme vestige autocratique, reste une période soumise à la subjectivité. On présente un modèle analytique différent de ce que serait un système oligarchique, à la validité trans-locale, en cherchant à montrer la façon dont l'histoire du Second Empire et de la Première République apparaitrait au moyen d'une approche préalable utilisant le modèle général.

  1. Desterrando formas poéticas en la República de Platón.

    Directory of Open Access Journals (Sweden)

    Sergio Ariza.

    2009-12-01

    Full Text Available Este artículo examina un aspecto seminal, pero sorprendente en la crítica de Platón de la poesía: Platón destierra a los contenidos, no sólo particular, y los autores, pero las formas poéticas también ellas mismas, en concreto la forma mimética. El análisis muestra que la principal razón para desterrar tales reside en el hecho de que Platón descubrió que la forma como la forma (con independencia de su contenido tiene un carácter autónomo y se rige por criterios estéticos y no moral. Estos criterios estéticos son incompatibles con la ideología que apoya la polis ideal. Esto pone de relieve el mérito del análisis de Platón de que no está en la evaluación de la actividad poética, sino en la identificación de las puramente estéticas y sus consecuencias sobre el programa político de la República

  2. Leptospirosis porcina: prevalencia serológica en establecimientos productores de la República Argentina

    Directory of Open Access Journals (Sweden)

    Jessica Petrakovsky M.

    2013-03-01

    Full Text Available Objetivo. Detectar la presencia de anticuerpos contra Leptospira sp en cerdos que no presentaban sintomatología clínica, pertenecientes a establecimientos de producción porcina ubicados en todo el territorio de la República Argentina. Materiales y métodos. La asignación de predios y muestras se realizó en forma proporcional a los registrados en cada provincia a lo largo de todo el país. En total se estudiaron 1.524 predios, de los cuales se tomaron 19.872 muestras de suero y en la primera etapa se procesaron 3.631 de los mismos. Este estudio toma en consideración zonas identificadas por provincia, municipio y predios. Los sueros fueron analizados por la técnica de MAT (prueba de microaglutinación. Resultados. El 30% de las muestras resultaron positivas a la prueba tamiz empleada (primera etapa del MAT. La mayoría presentó coaglutininas a dos o a tres serovariedades. Al realizar la titulación de los sueros (segunda etapa del MAT, el porcentaje de positividad se mantuvo, siendo los serovares de mayor prevalencia Castellonis e Icterohaemorrhagiae. El 90% de las muestras presentó un título final de 1:200. Conclusiones. La existencia de sueros positivos en todas las provincias indica el contacto de los animales con la leptospira a lo largo de todo el país.

  3. Representações cômicas da República no contexto do Getulismo

    Directory of Open Access Journals (Sweden)

    Elio Chaves Flores

    2001-01-01

    Full Text Available Neste artigo analiso as representações cômicas e discursivas da República e a trajetória política de Getúlio Vargas, a partir de uma narrativa que se assenta no método regressivo. Para isso, trabalhei com uma série de caricaturas publicadas em jornais e revistas na duração entre 1930 e 1954, confrontando a intertextualidade dessas imagens com alguns discursos satíricos e irônicos produzidos por memorialistas. Procuro demonstrar que há semelhança entre a inversão humorística e a textualidade da memória, quando inventam a respeito de seu tempo e dos outros imagens verossímeis.This article analyses the comic and discursive representations of the Brazilian Republic and Getúlio Vargas’ political career, starting from a narrative constructed in the regressive method. For that, I worked with a series of cartoons published in newspapers and magazines in the span of time between 1954 and 1930, matching the intertextuality of these images with some of the satiric and ironic speeches produced by witnesses. It is demonstrated there is likeness between the comic inversion and the textuality of the memory, when they invent concerning their time and other ones, the verisimilitude of the images.

  4. A loucura e a república no Brasil: a influência das teorias raciais

    Directory of Open Access Journals (Sweden)

    Audrey Rossi Weyler

    2006-03-01

    Full Text Available O presente artigo tem como objetivo discutir as modificações nas formas de compreensão e de enfrentamento da loucura na passagem do Império para a República, levando-se em conta a influência das teorias raciais importadas da Europa a partir de 1870. A adoção desses modelos teóricos cumpriu uma série de funções sociais e políticas referente a um projeto de nação. Neste contexto, as manifestações da loucura passaram a ser associadas à doença, à degeneração e ao risco e sofreram variadas medidas de opressão justificadas "cientificamente". Até hoje, as interpretações científicas do problema da "doença mental" continuam localizando a enfermidade no paciente. Ao reduzir a doença e a sua causa a uma problemática exclusivamente pessoal, sem que se considere o contexto socioeconômico e político da sua emergência, estas explicações configuram-se como ideologia.

  5. Les revistes bilingües a la Tortosa de la II República

    Directory of Open Access Journals (Sweden)

    M. Carme Gombau Domingo

    2016-06-01

    Full Text Available En l’àmbit de la premsa tortosina en català del primer terç del segle xx es donen dues actituds lingüístiques: la fabriana i la tortosinista. La primera, partidària del model de llengua de l’IEC, era minoritària als anys vint però es generalitza a partir dels anys trenta (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita; mentre que el tortosinisme, que es correspon amb una ideologia cada cop més localista i que eleva el «parlar tortosí» a la categoria de llengua, queda reduït durant la II República a tres revistes bilingües: La Zuda, Germanor i La Santa Cinta. There were two linguistic actitudes in the tortosine press of the first third in the 20th century: the fabriana amb the tortosinista. The fabriana, in favour of the IEC linguistic model, was in minority during the 20’s, but it became widespread from the 30’s (La Veu de Tortosa, La Veu Comarcal, Ara, Acció, Vida Tortosina i Lluita. The second, the tortosinista, had a local ideology and compared the tortosinisme talk as a complet language, but it was reduced during the ii Republic to three magazines: La Zuda, Germanor i La Santa Cinta.

  6. Interspecies extrapolation based on the RepDose database--a probabilistic approach.

    Science.gov (United States)

    Escher, Sylvia E; Batke, Monika; Hoffmann-Doerr, Simone; Messinger, Horst; Mangelsdorf, Inge

    2013-04-12

    Repeated dose toxicity studies from the RepDose database (DB) were used to determine interspecies differences for rats and mice. NOEL (no observed effect level) ratios based on systemic effects were investigated for three different types of exposure: inhalation, oral food/drinking water and oral gavage. Furthermore, NOEL ratios for local effects in inhalation studies were evaluated. On the basis of the NOEL ratio distributions, interspecies assessment factors (AF) are evaluated. All data sets were best described by a lognormal distribution. No difference was seen between inhalation and oral exposure for systemic effects. Rats and mice were on average equally sensitive at equipotent doses with geometric mean (GM) values of 1 and geometric standard deviation (GSD) values ranging from 2.30 to 3.08. The local AF based on inhalation exposure resulted in a similar distribution with GM values of 1 and GSD values between 2.53 and 2.70. Our analysis confirms former analyses on interspecies differences, including also dog and human data. Furthermore it supports the principle of allometric scaling according to caloric demand in the case that body doses are applied. In conclusion, an interspecies distribution animal/human with a GM equal to allometric scaling and a GSD of 2.5 was derived.

  7. República federal y patronato: el ascenso y descalabro de un proyecto

    Directory of Open Access Journals (Sweden)

    Brian Connaughton

    2010-06-01

    Full Text Available Este artículo aborda el patronato durante la primera república federal (1824-1834 desde la perspectiva de los debates que lo rodearon y dificultaron una solución por la cual el gobierno mexicano ejerciera los derechos de patrono de la Iglesia. La polémica sobre el patronato tuvo aspectos eclesiológicos, políticos y diplomáticos. Permite ver que México estaba inserto en una compleja dinámica nacional e internacional que acabaría frustrando la firma de un concordato.This article examines the trust established during the first federal republic (1824-1834 from the perspective of the debates that surrounded it and prevented reaching a solution whereby the Mexican government would act as owner of the Church. The polemic over the trust had ecclesiastic, political and diplomatic aspects. It showed that Mexico was inserted in a complex national and international dynamic that would end up preventing the signing of a concordat.

  8. Sistema de salud de República Dominicana The health system of Dominican Republic

    Directory of Open Access Journals (Sweden)

    Magdalena Rathe

    2011-01-01

    Full Text Available En este trabajo se describen las condiciones de salud de la República Dominicana y, con mayor detalle, el sistema de salud dominicano, incluyendo su estructura y cobertura, sus fuentes de financiamiento, el gasto en salud, los recursos físicos, materiales y humanos de los que dispone, las tareas de rectoría que desarrolla el Ministerio de Salud Pública y la generación de información. También se discuten la participación de los usuarios en la operación y evaluación del sistema de salud y las más recientes innovaciones implementadas, dentro de las que destacan la nueva Ley General de Salud, la nueva Ley de Seguridad Social y el Plan Decenal de Salud.This paper describes the health conditions in Dominican Republic and the characteristics of the Dominican health system, including its structure and coverage, its financial sources, the health expenditure, the physical, material and human resources available, the stewardship functions developed by the Ministry of Public Health and the generation of health information. The participation of health care users in the operation and evaluation of the system and the most recent policy innovations, including the new General Health Law, the new Social Security Law and the Decennial Health Plan are also discussed.

  9. Mapa educativo nacional. Una experiencia en la República Argentina

    Directory of Open Access Journals (Sweden)

    Horacio Rodolfo Bozzano

    2006-01-01

    Full Text Available El Proyecto Mapa Educativo Nacional (MEN es un SIG generado a partir del desarrollo e integración de 24 Mapas Educativos Provinciales sobre la base de un modelo conceptual general, con una visión dinámica de los 49.000 establecimientos educativos, así como de su contexto territorial. Los objetivos del trabajo son: a sistematizar los aportes al Proyecto MEN desde la teoría cartográfica, reconociendo instancias de concepción, construcción y comunicación de los mapas que lo integran, así como vinculaciones entre territorio, espacio y espacialidades emergentes de la concreción de la tarea; y b identificar en qué medida la concreción del Proyecto MEN en la República Argentina contribuye a fortalecer un enfoque dialéctico conocimiento-realidad sobre el territorio y la gestión aplicado a un objeto de estudio e intervención concreto de desarrollo institucional, con el propósito de promover un círculo virtuoso de transformación entre sujetos de cambio y agentes de desarrollo.

  10. La Historia de la Psicología en la República Dominicana

    Directory of Open Access Journals (Sweden)

    Josefina Zaite

    2013-01-01

    Full Text Available Este trabajo revisa el desarrollo de la psicología académica y profesional en la República Dominicana. Se da relevancia a los acontecimientos socio-históricos que sirvieron de contexto para el surgimiento y el avance de la psicología dominicana. Los aportes de los y las profesionales que contribuyen al impulso de los estudios y el ejercicio profesional de la psicología en nuestro país, son señalados y reconocidos. En el trabajo se aborda un análisis de los ámbitos de realización; así como de los logros y de las dificultades, en el avance tanto de la psicología académica, como del ejercicio profesional en la psicología dominicana. Finalmente, se consideran las perspectivas actuales de la psicología dominicana, para su desarrollo, su integración y proyección en el conjunto de la psicología en el Caribe y en Latinoamérica.

  11. Dos nuevas publicaciones de la Biblioteca Luis Ángel Arango del Banco de la República

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    1961-11-01

    Full Text Available La Biblioteca Luis-Ángel Arango, del Banco de la República, acaba de dar a la publicidad dos importantes trabajos que serán inapreciable ayuda para los investigadores de las letras colombianas, como son el volumen del Catálogo de su espléndida colección y Papeletas Bibliográficas para el estudio de la historia colombiana.

  12. Molecular Dynamics of Rab7::REP1::GGTase-II Ternary Complex and Identification of Their Putative Drug Binding Sites.

    Science.gov (United States)

    Sindhu, Meenakshi; Saini, Vandana; Piplani, Sakshi; Kumar, A

    2013-01-01

    The structure-function correlation of membrane proteins have been a difficult task, particularly in context to transient protein complexes. The molecular simulation of ternary complex of Rab7::REP1::GGTase-II was carried out to understand the basic structural events occurring during the prenylation event of Rab proteins, using the software YASARA. The study suggested that the C-terminus of Rab7 has to be in completely extended conformation during prenylation to reach the active site of RabGGTase-II. Also, attempt was made to find putative drug binding sites on the ternary complex of Rab7::REP1::GGTase-II using Q-SiteFinder programme. The comprehensive consensus probe generated by the program revealed a total of 10 major pockets as putative drug binding sites on Rab7::REP:: GGTase-II ternary complex. These pockets were found on REP protein and GGTase protein subunits. The Rab7 was found to be devoid of any putative drug binding sites in the ternary complex. The phylogenetic analysis of 60 Rab proteins of human was carried out using PHYLIP and study indicated the close phylogenetic relationship between Rab7 and Rab9 proteins of human and hence with further in silico study, the present observations can be extrapolated to Rab9 proteins. The study paves a good platform for further experimental verifications of the findings and other in silico studies like identifying the potential drug targets by searching the putative drug binding sites, generating pharmacophoric pattern, searching or constructing suitable ligand and docking studies.

  13. CARACTERIZACIÓN MOLECULAR MEDIANTE rep-PCR DE AISLADOS NATIVOS DE Bacillus thuringiensis, OBTENIDOS DE MUESTRAS DE SUELO

    Directory of Open Access Journals (Sweden)

    Fabi\\u00E1n Galvis

    2014-01-01

    Full Text Available Bacillus thuringiensis es una bacteria Gram-positiva formadora de esporas, que produ - ce cristales parasporales de naturaleza proteica, tóxicos contra diferentes órdenes de insectos y biodegradables e inocuos para otras especies. Esta investigación empleó el modelo experimen - tal, que mediante técnicas de observación permi - tió, la identificación microbiológica y bioquímica de B. thuringiensis a partir de muestras de suelo de los municipios de Cúcuta, El Zulia, Los Patios, San Cayetano y Villa del Rosario, Norte de Santander, Colombia, y su posterior caracteri - zación con los marcadores moleculares Bc-Rep y MB1. Se identificaron microbiológica y bioquí - micamente 10 aislados como B. thuringiensis ; los resultados del análisis filogenético mostraron diferencias significativas en los agrupamientos obtenidos con los marcadores Bc-Rep y MB1. Con Bc-Rep se registró un índice de similaridad bajo (18%, mientras que con el marcador MB1 se obtuvo un índice mayor de similitud, 58%. En este trabajo se evidenció una gran variabilidad genética entre los aislados, que mostraron a los marcadores Bc-Rep y MB1 como altamente efectivos para diferenciar cepas estrechamente relacionadas, convirtiéndose en una herramienta genética de gran valor para estudios de identifi-cación y diversidad en B. thuringiensis.

  14. Operación Sonrisa República Dominicana: 8 años de una intensa y positiva experiencia

    Directory of Open Access Journals (Sweden)

    Fernando De La Cruz-Acosta

    2016-03-01

    Full Text Available El objetivo de este artículo es dar a conocer el trabajo que, desde hace 8 años, está realizando un grupo de cirujanos plásticos perteneciente a la Fundación Operación Sonrisa República Dominicana a favor de los pacientes con malformaciones congénitas faciales, especialmente labio leporino y fisura palatina.

  15. Operación Sonrisa República Dominicana: 8 años de una intensa y positiva experiencia

    OpenAIRE

    Fernando De La Cruz-Acosta

    2016-01-01

    El objetivo de este artículo es dar a conocer el trabajo que, desde hace 8 años, está realizando un grupo de cirujanos plásticos perteneciente a la Fundación Operación Sonrisa República Dominicana a favor de los pacientes con malformaciones congénitas faciales, especialmente labio leporino y fisura palatina.

  16. La Segunda República Española: Acción y omisión en materia electoral

    Directory of Open Access Journals (Sweden)

    Enrique Cebrián Zazurca

    2016-01-01

    Full Text Available : El artículo realiza un recorrido por la normativa electoral vigente en la Segunda República Española; presenta las características principales de las distintas normas, resaltando los elementos del régimen electoral republicano. Una vez conocido el régimen, se abordan las principales claves del sistema electoral de la República concebido globalmente. Finalmente, el artículo pone en relación el sistema electoral con el sistema de partidos, tratando de valorar si aquel influyó en la crisis de la República. El trabajo sostiene que en la Segunda República Española no se aprobó nunca una ley electoral que pudiera considerarse como verdaderamente republicana.

  17. El Ecoturismo en los Humedales: Análisis de las Potencialidades de República Dominicana

    Directory of Open Access Journals (Sweden)

    Francisco Orgaz Agüera

    2014-04-01

    Full Text Available El turismo se configura como uno de los principales motores económicos de República Dominicana. En este sentido, el turismo de sol y playa es la principal tipología turística en el país. Aunque, República Dominicana cuenta con numerosas potencialidades turísticas para poner en marchas nuevas formas de turismo: Turismo gastronómico, turismo ornitológico, turismo cultural, ecoturismo, etc. El principal objetivo de esta investigación es analizar las potencialidades existentes en República Dominicana para desarrollar el ecoturismo en las zonas de humedales. La metodología ha consistido en un trabajo de campo, a través de las entrevistas, los grupos de discusión y la observación participante. Los resultados muestran las grandes potencialidades que tiene el país para desarrollar el ecoturismo en los humedales, y contribuir así, al desarrollo socioeconómico de las comunidades locales. 

  18. Overview of the relativistic electron precipitations (REP) observed on LEO satellites and ISS by Bulgarian build instruments

    Science.gov (United States)

    Dachev, Tsvetan

    Relativistic electron precipitation (REP) are observed by the R3D B2/B3 and RD3-B3 instruments during the flights of the Foton M2/M3 and “BION-M” № 1 satellite in 2005, 2007 and 2013, and by the R3DE/R instruments at the EXPOSE-E facility of the European Columbus module and at the EXPOSE-R facility of the Russian Zvezda module of the International Space Station (ISS) in the period from February 2008 till August 2010. The obtained dose rates strongly depend by the external and internal shielding of the detectors in the instruments. The highest dose rate reaching more than 20 mGy h (-1) was observed outside the ISS Zvezda module during the REP in April 2010 being the second largest in GOES history with a >2 MeV electron fluence event. REP doses behind relatively thick shielding are too small but may play considerable role during extra vehicular activity (EVA) when the cosmonauts/astronauts body is shielded only by the space suit.

  19. Enhanced nicking activity of Rep in presence of pre-coat protein of Mungbean yellow mosaic India virus.

    Science.gov (United States)

    Rouhibakhsh, A; Choudhury, N R; Mukherjee, S K; Malathi, V G

    2012-04-01

    Yellow mosaic disease causes severe yield loss in grain legumes in Indian subcontinent and south east Asia. The disease is caused by two virus species, Mungbean yellow mosaic India virus (MYMIV) and Mungbean yellow mosaic virus (MYMV). They have genome organization typical of Old World begomoviruses, the unique feature being the presence of an open reading frame (ORF) AV2 upstream of coat protein gene. In order to elucidate its function, ORF AV2 of blackgram isolate, Mungbean yellow mosaic India virus-[India:New Delhi:Blackgram 3:1991] MYMIV-[IN:ND:Bg3:91] and cowpea isolate, Mungbean yellow mosaic India virus-[India:New Delhi:Cowpea7:1998] MYMIV-[IN:ND:Cp7:98], respectively, were over expressed in Escherichia coli in fusion with maltose binding protein (MBP). The recombinant protein did not show efficient binding to DNA. However, both MBP-BgAV2 and MBP-CpAV2 proteins modulated nicking and ATPase activity of replication initiation protein (Rep). Even low concentration, 20 ng of MBP-BgAV2 and MBP-CpAV2 could bring 20 folds increase in nicking activity of Rep. Similarly in the presence of AV2 protein, two to three fold increase in ATPase activity was observed. It is hypothesized that AV2 protein may play a role of accessory protein modulating Rep activities.

  20. Revolución versus reforma educativa en la segunda república española. Elementos de ruptura

    Directory of Open Access Journals (Sweden)

    Juan Manuel FERNÁNDEZ SORIA

    2010-03-01

    Full Text Available RESUMEN: Están fuera de toda duda las conexiones existentes entre la República de 1931-35 y la de 1936-39. En este sentido estamos de acuerdo con quienes afirman que el estallido de la guerra del 36 es el resultado de un proceso que arranca del mismo año en que se proclama la II República, iniciándose ya entonces —como sostiene Andrés M. Kramer— la «mecánica de guerra civil». La educación republicana en tiempo de guerra no puede quedar fuera de esta consideración, porque aquélla sumerge sus cimientos más profundos en la política educativa de 1931-35. Efectivamente, muchas de las acciones educativas y culturales llevadas a cabo durante la guerra no tendrían fácil explicación si no se examina previamente la tarea de la República del 31 en estos mismos aspectos.

  1. Impact of Rate Design Alternatives on Residential Solar Customer Bills. Increased Fixed Charges, Minimum Bills and Demand-based Rates

    Energy Technology Data Exchange (ETDEWEB)

    Bird, Lori [National Renewable Energy Lab. (NREL), Golden, CO (United States); Davidson, Carolyn [National Renewable Energy Lab. (NREL), Golden, CO (United States); McLaren, Joyce [National Renewable Energy Lab. (NREL), Golden, CO (United States); Miller, John [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    With rapid growth in energy efficiency and distributed generation, electric utilities are anticipating stagnant or decreasing electricity sales, particularly in the residential sector. Utilities are increasingly considering alternative rates structures that are designed to recover fixed costs from residential solar photovoltaic (PV) customers with low net electricity consumption. Proposed structures have included fixed charge increases, minimum bills, and increasingly, demand rates - for net metered customers and all customers. This study examines the electricity bill implications of various residential rate alternatives for multiple locations within the United States. For the locations analyzed, the results suggest that residential PV customers offset, on average, between 60% and 99% of their annual load. However, roughly 65% of a typical customer's electricity demand is non-coincidental with PV generation, so the typical PV customer is generally highly reliant on the grid for pooling services.

  2. 40 CFR 81.88 - Billings Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control...

  3. 48 CFR 53.247 - Transportation (U.S. Commercial Bill of Lading).

    Science.gov (United States)

    2010-10-01

    .... Commercial Bill of Lading). 53.247 Section 53.247 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.247 Transportation (U.S. Commercial Bill of Lading). The commercial bill of lading is the preferred document for the transportation...

  4. 75 FR 78147 - Human Rights Day, Bill of Rights Day, and Human Rights Week, 2010

    Science.gov (United States)

    2010-12-14

    ... Proclamation 8616--Human Rights Day, Bill of Rights Day, and Human Rights Week, 2010 #0; #0; #0; Presidential... Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation Human Rights Day, Bill of Rights Day, and... Declaration of Independence, our Constitution, and our Bill of Rights. It is a belief that, while every nation...

  5. The RXL motif of the African cassava mosaic virus Rep protein is necessary for rereplication of yeast DNA and viral infection in plants

    Energy Technology Data Exchange (ETDEWEB)

    Hipp, Katharina; Rau, Peter; Schäfer, Benjamin [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany); Gronenborn, Bruno [Institut des Sciences du Végétal, CNRS, 91198 Gif-sur-Yvette (France); Jeske, Holger, E-mail: holger.jeske@bio.uni-stuttgart.de [Institut für Biomaterialien und biomolekulare Systeme, Abteilung für Molekularbiologie und Virologie der Pflanzen, Universität Stuttgart, Pfaffenwaldring 57, D-70550 Stuttgart (Germany)

    2014-08-15

    Geminiviruses, single-stranded DNA plant viruses, encode a replication-initiator protein (Rep) that is indispensable for virus replication. A potential cyclin interaction motif (RXL) in the sequence of African cassava mosaic virus Rep may be an alternative link to cell cycle controls to the known interaction with plant homologs of retinoblastoma protein (pRBR). Mutation of this motif abrogated rereplication in fission yeast induced by expression of wildtype Rep suggesting that Rep interacts via its RXL motif with one or several yeast proteins. The RXL motif is essential for viral infection of Nicotiana benthamiana plants, since mutation of this motif in infectious clones prevented any symptomatic infection. The cell-cycle link (Clink) protein of a nanovirus (faba bean necrotic yellows virus) was investigated that activates the cell cycle by binding via its LXCXE motif to pRBR. Expression of wildtype Clink and a Clink mutant deficient in pRBR-binding did not trigger rereplication in fission yeast. - Highlights: • A potential cyclin interaction motif is conserved in geminivirus Rep proteins. • In ACMV Rep, this motif (RXL) is essential for rereplication of fission yeast DNA. • Mutating RXL abrogated viral infection completely in Nicotiana benthamiana. • Expression of a nanovirus Clink protein in yeast did not induce rereplication. • Plant viruses may have evolved multiple routes to exploit host DNA synthesis.

  6. Platão e a poesia na República

    Directory of Open Access Journals (Sweden)

    Maria da Penha Villela-Petit

    2003-06-01

    Full Text Available Platão não é o iniciador, e sim o herdeiro da "velha divergência" entre filósofos e poetas. A motivação ético-teológica, que já animava Xenófanes,vai se reatualizar na República. Para poder apreciar o sentido dessa reatualização, importa que não se considere o Livro X isoladamente, mas se atente para os primeiros livros do diálogo. Neles, e com vistas a uma melhor determinação do justo -que é o que está em pauta-, Platão mostra a necessidade de se discutir as afirmações dos poetas. Trata-se assim de destituí-los da autoridade de que ainda gozam na educação e na opinião comum. Só graças à discussão filosófica e a uma educação por ela inspirada -o que pressupõe a produção ou a seleção de mitos- é que se pode esperar uma maior realização da justiça, tanto no plano do indivíduo (do governo de sua alma quanto no nível da cidade. A leitura aqui proposta das "razões" de Platão na República não impede que reconheçamos a importância da tragédia para a compreensão da existência humana, inclusive no que toca à idéia do divino.Plato is not the initiator, but rather the heir of the "old quarrel", between philosophers and poets. The ethical and theological motivation that drove Xenophanes is brought to date in the Republic. In order to realize that, one must take into account the whole of the dialogue - where the definition of justice is at stake - and, more precisely, its first books. There, Plato shows how important it is to put the poets' claims to question. The point is, after all, to deprive them of the authority they enjoy in what concerns educational matters as well as with public opinion. It is only through an education which is inspired by philosophical questioning - which also implies the production and selection of myths - that one can expect more justice both on the individual (the gouvernment of his soul and on the city levels. The reading we propose of Plato's "reasons" in the Republic does

  7. Addressing medical coding and billing part II: a strategy for achieving compliance. A risk management approach for reducing coding and billing errors.

    Science.gov (United States)

    Adams, Diane L; Norman, Helen; Burroughs, Valentine J

    2002-06-01

    Medical practice today, more than ever before, places greater demands on physicians to see more patients, provide more complex medical services and adhere to stricter regulatory rules, leaving little time for coding and billing. Yet, the need to adequately document medical records, appropriately apply billing codes and accurately charge insurers for medical services is essential to the medical practice's financial condition. Many physicians rely on office staff and billing companies to process their medical bills without ever reviewing the bills before they are submitted for payment. Some physicians may not be receiving the payment they deserve when they do not sufficiently oversee the medical practice's coding and billing patterns. This article emphasizes the importance of monitoring and auditing medical record documentation and coding application as a strategy for achieving compliance and reducing billing errors. When medical bills are submitted with missing and incorrect information, they may result in unpaid claims and loss of revenue to physicians. Addressing Medical Audits, Part I--A Strategy for Achieving Compliance--CMS, JCAHO, NCQA, published January 2002 in the Journal of the National Medical Association, stressed the importance of preparing the medical practice for audits. The article highlighted steps the medical practice can take to prepare for audits and presented examples of guidelines used by regulatory agencies to conduct both medical and financial audits. The Medicare Integrity Program was cited as an example of guidelines used by regulators to identify coding errors during an audit and deny payment to providers when improper billing occurs. For each denied claim, payments owed to the medical practice are are also denied. Health care is, no doubt, a costly endeavor for health care providers, consumers and insurers. The potential risk to physicians for improper billing may include loss of revenue, fraud investigations, financial sanction

  8. Discurso de orden.Tribunal supremo de justicia de la república Bolivariana de Venezuela

    Directory of Open Access Journals (Sweden)

    José Manuel Delgado Ocando

    2001-01-01

    Full Text Available José Manuel Delgado Ocando, nos presenta un original y brillante análisis de la realidad política venezolana. Bien es sabido que a raíz de la elección presidencial de Hugo Chávez Frías, éste convoca a un referéndum popular con la expresa intención de constituir un nuevo orden constitucional. Tal inusual experiencia de la ciudadanía en la participación de los “asuntos de Estado”, generó no pocas controversias sobre el conflicto de competencias entre la Asamblea Nacional Constituyente (poder constituyente y el Congreso de la República (poder constituido. No previsto en la Constitución de 1961 este inédito protagonismo popular y la coexistencia de dos regímenes constitucionales distintos, le toca a la Corte Suprema de Justicia legislar sobre este caso particular teniendo que apelar a la doctrina de la supraconstitucionalidad a fin de dirimir el conflicto normativo y ratificar la legalidad de la consulta referendaria que da origen a la Asamblea Nacional Constituyente. El autor se vale de una compleja hermenéutica jurídico-política para interpretar este inédito fenómeno de la filosofía política moderna que se ha vivido en Venezuela, así como para confirmar su confianza en la producción originaria del derecho cuando ésta es reclamada por la soberanía popular.

  9. "Sobre la justicia en el libro "La República" de Platón"

    Directory of Open Access Journals (Sweden)

    Walter Olivari

    2008-01-01

    Full Text Available La justicia, ha sido siempre un tema presente en la filosofía y con más notoriedad en la filosofía clásica, por ello resulta saludable, atractivo y de valor el análisis de los textos griegos al respecto. En este punto, Platón es quizás el más estudiado, siempre sus diálogos resultan útiles para quien recorre sus páginas, ya convertidas en verdaderos monumentos de la filosofía, con pasajes y afirmaciones hasta hoy irrefutables, además haciendo de su maestro Sócrates un personaje invalorable para la sabiduría universal. La innata ansia por una vida mejor, empuja al hombre casi siempre a la búsqueda de un mundo sin defectos. Esta es la razón de sus ilusiones utópicas de alcanzar justica, entendida ella como la perfecta armonía en la convivencia social. De la producción platónica, extensa, variada y valiosa, por todo lo que trata y por su sobrevivencia al paso de los años, la obra La República ocupa un lugar de preferencia, por eso estudiar sus paginas y repasar, tanto como re-pensar sus conceptos, es buen estimulo para quienes desean conocer temas de trascendencia en Filosofía, Derecho o afines. Volver a los clásicos es siempre un deber, ellos siempre son fascinantes y sus enseñanzas perduran con gran lozanía, a prueba de todo elemento corrosivo, por tanto no hay pretexto que valga, como para no estudiar, lo que sobre la justicia con genialidad nos comentaron hace ya tantos años.

  10. High burnup effects on fuel behaviour under accident conditions: the tests CABRI REP-Na

    Science.gov (United States)

    Schmitz, Franz; Papin, Joelle

    A large, performance based, knowledge and experience in the field of nuclear fuel behaviour is available for nominal operation conditions. The database is continuously completed and precursor assembly irradiations are performed for testing of new materials and innovative designs. This procedure produces data and arguments to extend licencing limits in the permanent research for economic competitiveness. A similar effort must be devoted to the establishment of a database for fuel behaviour under off-normal and accident conditions. In particular, special attention must be given to the so-called design-basis-accident (DBA) conditions. Safety criteria are formulated for these situations and must be respected without consideration of the occurrence probability and the risk associated to the accident situation. The introduction of MOX fuel into the cores of light water reactors and the steadily increasing goal burnup of the fuel call for research work, both experimental and analytical, in the field of fuel response to DBA conditions. In 1992, a significant programme step, CABRI REP-Na, has been launched by the French Nuclear Safety and Protection Institute (IPSN) in the field of the reactivity initiated accident (RIA). After performing the nine experiments of the initial test matrix it can be concluded that important new findings have been evidenced. High burnup clad corrosion and the associated degradation of the mechanical properties of the ZIRCALOY4 clad is one of the key phenomena of the fuel behaviour under accident conditions. Equally important is the evidence that transient, dynamic fission gas effects resulting from the close to adiabatic heating introduces a new explosive loading mechanism which may lead to clad rupture under RIA conditions, especially in the case of heterogeneous MOX fuel.

  11. Bill restricts abortion blockades. Clinic violence is target of action.

    Science.gov (United States)

    1993-11-17

    On November 16, 1993, the US Senate voted approval, by 69 to 30 members, to impose stiff penalties on those obstructing access to abortion clinics. The penalties include up to 1 year in jail and a $100,000 fine for first violent offenses. Obstruction without violence would lead to a fine of $10,000 and 6 months in jail. The legislation was deemed necessary after the murder of a doctor in Florida and the wounding of another doctor in Kansas. Democratic Senator Edward Kennedy said that those who do not obstruct access have nothing to fear. Support came not only from abortion rights advocates, but from those against lawlessness in the pro-life movement. Maryland's Democratic Senators Mikulski and Sarbanes and California's Democratic Senator Barbara Boxes supported the bill, as well as Attorney General Janet Reno and President Clinton. House Speaker Thomas S. Foley announced that the House would consider its version of the bill on November 18, 1993. The original version was changed to reduce fines for nonviolent offenders from $100,000 to $10,000. Opponents argued that the legislation treated peaceful protesters as felons, and was directed in a singular=sided way with no regard to civil disobedience by animal rights activists, antinuclear protesters, and AIDS activists. North Carolina Republican Senator Jesse Helms thought that the Supreme Court would find the bill unconstitutional. Other arguments were that civil disobedience should be allowed for anti-abortion protesters, as it was allowed for civil rights protesters such as Dr. Martin Luther King, Jr. Senator Kennedy pointed out the Dr. King was trying to secure a constitutional right, unlike anti-abortion protesters who were trying to deny a constitutional right.

  12. Diets of nestling gull-billed terns in coastal Virginia

    Science.gov (United States)

    Erwin, R.M.; Eyler, T.B.; Hatfield, J.S.; McGary, S.

    1998-01-01

    We studied the diets of nestling Gull-billed Terns (Sterna nilotica) at colonies in coastal Virginia during the breeding seasons of 1995 and 1996 as part of a long-term study of the species. No previous quantitative assessments had been made of diets of this species anywhere along the Atlantic Coast, and only a few observations had been reported from other coastal areas in the southern United States. During 80 h of observations over the two seasons, 757 feeding observations were made, primarily at two colony sites. We examined how prey type (fish, marine invertebrates, terrestrial prey) and size were influenced by year, tide cycle, season (early and late) and age of the young (small chicks 7 d). We did not find significant year differences, but all other factors revealed statistically significant results. Older (>7 d) chicks were fed relatively more terrestrial and marine invertebrate prey than were younger chicks. In June (early season), fewer fish and terrestrial prey were fed to chicks than later (July-August). Most prey were less than one bill length in size, with the majority of the smallest prey being marine invertebrates. Tide cycle influenced prey delivered with terrestrial prey becoming relatively more important during high and ebb periods than during low and flood tides when aquatic prey dominated. The major marine invertebrate prey taken was the fiddler crab (Uca spp.). Terrestrial prey consisted mostly of large odonates and orthopterans. Unlike earlier reports from Europe, we found no regurgitated food pellets in any of the colonies in either year. This study confirms that the Gull-billed Tern is an extremely opportunistic feeder and has adapted to a variety of habitats, helping to explain its cosmopolitan distribution.

  13. Gisela Cramer y Ursula Prutsch, editoras. ¡Américas unidas! Nelson A. Rockefeller’s Office of Inter-American Affairs (1940-46

    Directory of Open Access Journals (Sweden)

    David Andrew Corcoran

    2014-03-01

    Full Text Available Un tema muy poco conocido y con poca frecuencia estudiado es la constitución de la Oficina de Asuntos Interamericanos (OIAA, en inglés, que orquesto una reestructuración de las relaciones entre Estados Unidos y América Latina durante de la Segunda Guerra Mundial. Abandonando de esta manera los limites de la diplomacia tradicional (gobierno a gobierno, los programas OIAA pusieron al gobierno de EE.UU. y a sus ciudadanos por primera vez en contacto directo con sectores amplios del pueblo latinoamericano. Bajo la dirección del joven Nelson Rockefeller y con la clara intención de frenar la influencia del poder nazi y del eje en la región, la OIAA dio sustento a la política del buen vecino.

  14. Gisela Cramer y Ursula Prutsch, editoras. ¡Américas unidas! Nelson A. Rockefeller’s Office of Inter-American Affairs (1940-46

    Directory of Open Access Journals (Sweden)

    David Andrew Corcoran

    2013-07-01

    Full Text Available Un tema muy poco conocido y con poca frecuencia estudiado es la constitución de la Oficina de Asuntos Interamericanos (OIAA, en inglés, que orquesto una reestructuración de las relaciones entre Estados Unidos y América Latina durante de la Segunda Guerra Mundial. Abandonando de esta manera los limites de la diplomacia tradicional (gobierno a gobierno, los programas OIAA pusieron al gobierno de EE.UU. y a sus ciudadanos por primera vez en contacto directo con sectores amplios del pueblo latinoamericano. Bajo la dirección del joven Nelson Rockefeller y con la clara intención de frenar la influencia del poder nazi y del eje en la región, la OIAA dio sustento a la política del buen vecino.

  15. Power System Reliability Assessment by Analysing Voltage Dips on the Blue Horizon Bay 22KV Overhead Line in the Nelson Mandela Bay Municipality

    Science.gov (United States)

    Lamour, B. G.; Harris, R. T.; Roberts, A. G.

    2010-06-01

    Power system reliability problems are very difficult to solve because the power systems are complex and geographically widely distributed and influenced by numerous unexpected events. It is therefore imperative to employ the most efficient optimization methods in solving the problems relating to reliability of the power system. This paper presents a reliability analysis and study of the power interruptions resulting from severe power outages in the Nelson Mandela Bay Municipality (NMBM), South Africa and includes an overview of the important factors influencing reliability, and methods to improve the reliability. The Blue Horizon Bay 22 kV overhead line, supplying a 6.6 kV residential sector has been selected. It has been established that 70% of the outages, recorded at the source, originate on this feeder.

  16. Multiculturalism in the New Japan. Crossing the Boundaries Within, H.H. Nelson Graburn, John Ertl, Kenji R. Tierney (éds

    Directory of Open Access Journals (Sweden)

    Antonio Guerreiro

    2012-01-01

    Full Text Available Ce volume fait suite à la conférence intitulée : « Japan : Crossing the Boundaries Within », organisée en 2002 à l’université de Californie, à Berkeley, dont le thème principal était l’apport des immigrés – surtout asiatiques – dans la formation d’un « Nouveau Japon », au tournant du troisième millénaire . La cheville ouvrière du livre, Nelson Graburn, anthropologue, est actuellement conservateur des collections d’ethnologie nord-américaine au P. Hearst Museum of Anthropology de Berkeley, il ...

  17. A cinema of presence and proximity: Gunvor Nelson's collage films and the aesthetics of the signaletic material before the electronic signal

    Directory of Open Access Journals (Sweden)

    John Sundholm

    2012-06-01

    Full Text Available This essay argues for the importance of an intersubjective and impure film theory in which the signal and the signaletic is considered as figures for approaching film. This in order to make the argument that the signaletic mode indeed enables a novel perspective on moving image history. The aesthetics of the signaletic has thus a history preceding that of electronic media, in particular when it comes to animation and experimental film. When constructing such an archaeology, however, dichotomies into sign and signal should be avoided; otherwise, the complexity of many of the films is reduced. In order to illuminate the latter point, four films by Gunvor Nelson is analyzed (both analog and digital, showing not only how both sign and signal interact but also how the aesthetics of the signal and the signaletic material is not dependant on the electronic as such.

  18. 收藏艺术品的艺术品——Nelson-Atkins艺术博物馆扩建新馆Bloch

    Institute of Scientific and Technical Information of China (English)

    王怀英; Andy; Ryan(摄影)

    2007-01-01

    Nelson-Atkins艺术博物馆是美国最著名的艺术博物馆之一,位于美国密苏里州的堪萨斯城。博物馆于1930年破土动工.1933年首次对外开放。由于当时正处于经济大萧条时期,全球艺术品市场涌现出大量的低价倾销的珍贵艺术品,而收购者很少,该馆因此在很短的时间内收购了大量的艺术品,奠定了在艺术博物馆中的地位。

  19. Hormonal secretion and quality of life in Nelson syndrome and Cushing disease after long acting repeatable octreotide: a short series and update.

    Science.gov (United States)

    Arregger, Alejandro L; Cardoso, Estela M L; Sandoval, Olga B; Monardes Tumilasci, Elida G; Sanchez, Rocío; Contreras, Liliana N

    2014-01-01

    Clinical management of persistent adrenocorticotropin hormone (ACTH) excess in Nelson syndrome (NS) and Cushing disease (CD) remains a challenge. Somatostatin and its analogs as octreotide decrease ACTH secretion through somatostatin receptors of pituitary cells. To our knowledge, there are no reports on the effect of long-acting repeatable octreotide (oct-lar) on hormonal secretion and quality of life in patients with NS and CD who failed conventional therapy. Herein, we describe the effects of treatment with oct-lar (20 mg/month intramurally) in 1 woman with NS and 2 women with persistent CD. Oct-lar therapy reduced ACTH secretion and improved the quality of life in NS patient. By contrast, in CD patients, it failed to control ACTH and cortisol secretion, and the quality of life remained unchanged.

  20. A construção do afeto nos filmes "Nelson Freire" e "Santiago" de João Moreira Salles

    OpenAIRE

    Oliveira, Érika Bauer de

    2013-01-01

    A busca do olhar afetivo nos documentários de João Moreira Salles "Nelson Freire" e "Santiago" a partir da investigação de uma trajetória autoral no documentário mundial, tendo como referências, clássicos como Nanook of the Earth, de Flaherty, Primárias, de Robert Draw e Richard Leacock e Crônica de um verão, de Jean Rouch e Edgar Morin, além de O Fim e o Principio e Jogo de Cena, de Eduardo Coutinho. Encontrar dentro da história, o percurso de um olhar mais afetivo, e elucidar o caminho de s...

  1. Custeio dos gastos no serviço público de saúde: estudo de caso no Hospital Nelson Salles

    OpenAIRE

    Warley Francisco de Araújo Pereira

    2014-01-01

    A dissertação tem como objetivo aplicar um método de custeio aos gastos atribuídos, pelo Hospital Nelson Salles, na execução do serviço público de saúde, em apoio ao Município Engenheiro Paulo de Frontin. Para a realização deste trabalho, o estudo utilizou-se da pesquisa bibliográfica para fundamentar e ilustrar o tema proposto, bem como, do método exploratório descritivo para reconhecer a situação da instituição e identificar uma metodologia de controle dos custos adequada à realidade da org...

  2. Empirical Analysis of Nelson-Siegel Model in Chinese Inter-bank Government Bonds Market%中国银行间国债市场利率期限结构实证分析——基于Nelson-Siegel模型

    Institute of Scientific and Technical Information of China (English)

    文忠桥

    2013-01-01

    利用粒子群算法,以2007年1月-2009年12月中国银行间国债市场的日交易数据模拟Nelson-Siegel模型,通过构建参数β1和β2的AR(2)模型对利率期限结构进行预测,样本内的预测结果比较理想,但样本外的预测绩效不佳.

  3. Representação dos monstros e monstruosidades na literatura e no cinema: transformações em A terceira margem do rio, de Nelson Pereira dos Santos = The representation of monsters and monstrosities in Literature and Cinema: transformation in A terceira margem do rio, by Nelson Pereira dos Santos

    Directory of Open Access Journals (Sweden)

    Souto, Generosa

    2011-01-01

    Full Text Available Tem este texto a intenção de discutir em que medida ocorre a representação dos monstros e das monstruosidades como construção discursiva no filme A Terceira Margem do Rio (1994, de Nelson Pereira dos Santos, que reúne, num só corpo, seis das Primeiras Estórias, de Guimarães Rosa, Sequência, Fatalidade, A menina de lá, As margens da alegria e Os Irmãos Dagobé

  4. Treasury bill rates in the 1970s and 1980s

    OpenAIRE

    Patric H. Hendershott; Joe Peek

    1991-01-01

    As is widely recognized, real interest rates in the early 1980s were at peaks not witnessed since the late 1920s. Less well perceived is the sharp decline in real interest rates since 1984. By 1986-88, real interest rates were back at their average levels of the previous quarter century. This paper seeks to identify the underlying determinants of the major movements in real six-month Treasury bill rates. The rise in real interest rates between the middle 1970s and early 1980s, not surprisingl...

  5. Aplicación del modelo polinomial en la evaluación de la uniformidad de riego del aspersor autocompensado Nelson R10

    Directory of Open Access Journals (Sweden)

    Fanny del Rocío Rodríguez-Jarama

    2015-01-01

    Full Text Available Los métodos de evaluación de la uniformidad de riego estiman las condiciones hidráulicas de funcionamiento del sistema de riego y su influencia en la aplicación de láminas de agua, con base en las necesidades hídricas de un cultivo. El modelo de evaluación utilizado en la presente investigación fue el polinomial. El ensayo evaluó el funcionamiento del sistema de riego con 4 presiones de operación distintas, medidas a la salida de la válvula del módulo de riego, y por cada presión de operación se tomaron 16 datos de caudales, en 5 módulos de riego instalado con el aspersor autocompensado Nelson R10. Como resultado se obtuvo el coeficiente de uniformidad, el coeficiente de distribución, el área adecuadamente irrigada y el factor de adecuación del riego. Uno de los principales resultados fue la no existencia de diferencia significativa entre las presiones mientras esta se mantengan en el rango de autocompensación; por otro lado, en el coeficiente de distribución sí existen diferencias significativas entre los tratamientos, a pesar de que todos dan valores mayores al 90%, en contraste con los porcentajes del área relativa adecuadamente regada, que no superan el 50% en ninguno de los tratamientos. Con lo anterior se pudo validar y verificar que el aspersor Nelson R10 autocompensado, una vez instalado en campo, cumple con las características técnicas de operación expuestas en el catálogo del fabricante, sin embargo, sí se debe manejar y controlar la lámina de riego aplicada.

  6. Sedimentary Records of Hyperpycnal Flows and the Influence of River Damming on Sediment Dynamics of Estuaries: Examples from the Nelson, Churchill, Moisie and Sainte-Marguerite Rivers (Canada)

    Science.gov (United States)

    St-Onge, G.; Duboc, Q.; Boyer-Villemaire, U.; Lajeunesse, P.; Bernatchez, P.

    2015-12-01

    Sediment cores were sampled in the estuary of the Nelson and Churchill Rivers in western Hudson Bay, as well as in the estuary of the Moisie and Sainte-Marguerite Rivers in Gulf of St. Lawrence in order to evaluate the impact of hydroelectric dams on the sedimentary regime of these estuaries. The gravity cores at the mouth of the Nelson River recorded several cm-thick rapidly deposited layers with a reverse to normal grading sequence, indicating the occurrence of hyperpycnal flows generated by major floods during the last few centuries. These hyperpycnal flows were probably caused by ice-jam formation, which can increase both the flow and the sediment concentration following the breaching of such natural dams. Following the construction of hydroelectric dams since the 1960s, the regulation of river discharge prevented the formation of hyperpycnal flows, and hence the deposition of hyperpycnites in the upper part of the cores. In the core sampled in the estuary of the Churchill River, only one hyperpycnite was recorded. This lower frequency may be due to the enclosed estuary of the Churchill River, its weaker discharge and the more distal location of the coring site.In the Gulf of St. Lawrence, grain size measurements allowed the identification of a major flood around AD 1844±4 years in box cores from both the Sainte-Marguerite and Moisie Rivers, whereas a drastic decrease in variations in the median grain size occurred around AD ~1900 in the estuary of the Sainte-Marguerite River, highlighting the offshore impact of the SM1 dam construction in the early 1900s. Furthermore, sedimentological variations in the box cores from both estuaries have been investigated by wavelet analysis and the sharp disappearance of high frequencies around AD 1900 in the estuary of the dammed river (Sainte-Marguerite River), but not in the estuary of the natural river (Moisie River), also provides evidence of the influence of dams on the sedimentary regime of estuaries.

  7. Beyond the game: the legacy of Bill Masterton.

    Science.gov (United States)

    Bonfield, Christopher M; Kondziolka, Douglas

    2016-07-01

    Bill Masterton is the only man to die of injuries sustained in a National Hockey League (NHL) game. He remains the last fatality in any professional team sport involving a direct in-game injury in North America. While Masterton was originally thought to have suffered a fatal brain injury while being checked on the ice, later analysis of the case revealed evidence of second-impact syndrome and the effects of prior concussions. Masterton's death sparked both an immediate debate in the NHL on whether helmets should be compulsory and the NHL's first vote on mandatory helmet use. Although the subject of mandated helmet use met with resistance in the 10 years after Masterton's death, especially from hockey owners and coaches, the NHL finally legislated helmet use by all players entering the league beginning in the 1979-1980 season. Several awards, including one recognizing the NHL player who best exemplifies the qualities of perseverance, sportsmanship, and dedication to hockey, have been created in memory of Masterton. However, his legacy extends far beyond the awards that bear his name. His death was the seminal event bringing head safety to the forefront of a game that was both unready and unwilling to accept change. An increase in mainstream media attention in recent years has led to unprecedented public awareness of brain injury and concussion in hockey and other sports. Advances in the diagnosis and treatment of head injury in sports have occurred recently, the impetus for which started over 45 years ago, when Bill Masterton died.

  8. Water Label to Improve Water Billing in Spanish Households

    Directory of Open Access Journals (Sweden)

    Ana Castillo-Martinez

    2014-05-01

    Full Text Available A significant decrease in water consumption has been achieved in recent years thanks to different campaigns run by different institutions in Spain. However, most citizens do not have a very clear idea about whether or not they are efficiently using water. To solve this situation, this paper aims is to develop two water labels in order to improve the current water billing. These water labels evaluate the total water consumption and the domestic hot water consumption. To make the tags, several research studies were tackled for establishing consumer trends and behavior patterns. Furthermore, a survey and data collection were conducted to obtain updated values to validate information obtained from previous studies. The result are two water labels that establish six different levels to graphically show the efficiency, and they also include a comparison with the average consumption by customers of the same province. To ensure that the benefits of this evaluation are available to citizens, its inclusion on the water bill is proposed.

  9. Heat loss may explain bill size differences between birds occupying different habitats.

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    Russell Greenberg

    Full Text Available BACKGROUND: Research on variation in bill morphology has focused on the role of diet. Bills have other functions, however, including a role in heat and water balance. The role of the bill in heat loss may be particularly important in birds where water is limiting. Song sparrows localized in coastal dunes and salt marsh edge (Melospiza melodia atlantica are similar in size to, but have bills with a 17% greater surface area than, those that live in mesic habitats (M. m. melodia, a pattern shared with other coastal sparrows. We tested the hypotheses that sparrows can use their bills to dissipate "dry" heat, and that heat loss from the bill is higher in M. m. atlantica than M. m. melodia, which would indicate a role of heat loss and water conservation in selection for bill size. METHODOLOGY/PRINCIPAL FINDINGS: Bill, tarsus, and body surface temperatures were measured using thermal imaging of sparrows exposed to temperatures from 15-37°C and combined with surface area and physical modeling to estimate the contribution of each body part to total heat loss. Song sparrow bills averaged 5-10°C hotter than ambient. The bill of M. m atlantica dissipated up to 33% more heat and 38% greater proportion of total heat than that of M. m. melodia. This could potentially reduce water loss requirements by approximately 7.7%. CONCLUSIONS/SIGNIFICANCE: This >30% higher heat loss in the bill of M. m. atlantica is independent of evaporative water loss and thus could play an important role in the water balance of sparrows occupying the hot and exposed dune/salt marsh environments during the summer. Heat loss capacity and water conservation could play an important role in the selection for bill size differences between bird populations and should be considered along with trophic adaptations when studying variation in bill size.

  10. Hacia una república conservadora : el programa político del Partido Agrario Español

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    Luis Teófilo Gil Cuadrado

    2005-01-01

    Full Text Available El Partido Agrario Español (PAE, fundado en enero de 1934 y presidido por José Martínez de Velasco, representó, dentro de la II República española, una alternativa conservadora y, al tiempo, leal al régimen. El programa político del PAE aceptaba la República —a diferencia de otros partidos derechistas del momento, como la CEDA y los monárquicos— y defendía la unidad nacional, el establecimiento de una segunda Cámara legislativa, la protección de la agricultura y la industria mediante aranceles, el libre comercio dentro de las fronteras nacionales y la revisión de algunas leyes del primer bienio como la Reforma Agraria de 1932. El objetivo era la configuración de una República conservadora distinta, en aspectos fundamentales, a la diseñada por la Constitución de 1931 y la legislación del bienio social-republicano.The Spanish Agrarian Party (Partido Agrario Español, PAE, founded in january of 1934 and presided by José Martínez de Velasco, was, in the political life of the Spanish Second Republic, a conservative and republican option. The agrarian program accepted the republican regime —in opposition to other conservative parties, like the CEDA or the monarchists— and defended the national union, the establishment of a Senate, the protection of the national agriculture and industry trough tariffs, the free trade in the Spanish market and the revision of some laws voted in the first biennium like the Agrarian Reform, promulgated in 1932. The idea was to establish a conservative Republic, different, in some fundamental aspects, of the regime designed by the Constitution of 1931 and the legislation approved during the socialist-republican biennium.

  11. Proyectos de parcelas con servicios desarrollados por el INVI en la República Dominicana

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    Pou Howley, Carlos

    1984-07-01

    Full Text Available Santo Domingo, the capital of the Dominican Republic, has not escaped the phenomenon of urban growth and the concentration of large slum areas or hovels, mainly due to the migratory movements of the peasants who have been driven from the country. As a viable solution to the enormous problem of housing in this city, INVI, with the participation of the World Bank, is putting forward projects for lots supplied with services in which infrastructure services are installed on urban land and plots or parcels of land are given to families so that they can build or complete their houses. These projects are located in places registering a greater tendency towards development. The urban plan formulated in both projects is of an eminently pedestrian nature with a reduced thoroughfare for vehicles. In the pedestrian precinct, it was possible to lay down what have been called mini-parks, which involve widening the pedestrian thoroughfare and, in addition to constituting green areas distributed throughout the projects, they also reinforce the idea of a neighbourhood. Because of the scope of the projects, a series of installations have been provided to maintain their own community services, as well as commercial and institutional ones, which are distributed strategically.Santo Domingo, capital de la República Dominicana, no ha escapado al fenómeno del crecimiento urbano y a la concentración de grandes tugurios o arrabales, debido principalmente a los movimientos migratorios de los campesinos expulsados del campo. Como una solución viable al gran problema de la vivienda de esta ciudad, el INVI, con la participación del Banco Mundial, plantea proyectos de parcelas con Servicios en los cuales se instalan servicios de infraestructura en tierras urbanas y se proporcionan parcelas o solares a familias para que éstas construyan o completen sus viviendas. Se ubican estos proyectos en sitios que acusan una mayor tendencia de desarrollo. El esquema urbano

  12. A natureza dos números na República de Platão

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    Anastácio Borges de Araújo Jr.

    2010-12-01

    Full Text Available É incontestável a presença das matemáticas nos diálogos de Platão, todavia o alcance e o sentido desta presença é matéria de controvérsia entre os especialistas. Alguns acreditam que os temas matemáticos empregados nos diálogos são fantasias matemáticas, outros defendem baseados, sobretudo no testemunho de Aristóteles, que Platão teria substituído na sua hipótese as formas inteligíveis pelos números ideais. Sem tomar partido de antemão nestas querelas, o que propomos aqui é uma investigação acerca da natureza dos números fundamentada exclusivamente nos textos de Platão, particularmente orientada por uma passagem do livro VII do diálogo República(525 b11- c3, em que Sócrates diz o seguinte: "Seria, portanto, conveniente colocar este estudo, ò Glaucon, dentro de uma legislação e persuadir aqueles que vão participar das grandes coisas na cidade a irem ao cálculo e a aplicarem-se a ele, não nos seus afazeres privados, mas até chegarem à contemplação da natureza dos números através da própria intelecção (...".The presence of the mathematics in Plato's dialogues is unquestionable. However, its reach and sense is controversial for some specialists. Some believe that the mathematical themes employed in the dialogues are mathematical fantasies; on the other hand, others defend, based on the Aristotle's testimonies, that Plato would have substituted the intelligible forms by the ideal numbers in his hypothesis. Having not taken part in the quarrel, we propose an investigation on the nature of the numbers based exclusively in Plato's texts, particularly oriented by the a passage in book VII of Republic (525 b11 - c3, in which Socrates says: "Then it would be fitting, Glaucon, to set this study down in law and persuade those who are going to participate in the greatest things in the city to go to calculation and to take it up, not after the fashion of private men, but stay with it until they come to the

  13. Galeguismo, agro e agrarismo na Galicia da II República

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    Cabo Villaverde, Miguel

    2009-12-01

    Full Text Available The Partido Galeguista (PG was created in December 1931 as the expression of Galician nationalism during the Second Republic (1931-1936. Prior to that, the Galician nationalists had been very influential in the cultural sphere but rather powerless from a political point of view. The PG regarded agriculture and peasantry as a priority, not only because of their objective importance in the Galician economy and society in the 1930s but also because they were seen as the bulwarks of the national identity. In fact, the characteristics, needs and paths of development of the Galician agrarian sector were usually defined as opposed to those of the rest of Spain. It is then understable that the PG tried to win the agrarian unions over, and that it is arguable that it had plenty of common features with the so-called Agrarian Parties in other European regions.

    O Partido Galeguista (PG foi creado en decembro de 1931 como expresión do nacionalismo galego durante a Segunda República (1931-1936. Con anterioridade, os nacionalistas galegos foron moi influíntes no eido cultural pero maiormente inoperantes dende o punto de vista político. O PG consideraba a agricultura e o campesiñado como unha prioridade, non só pola súa importancia obxectiva na economía e sociedade galegas dos anos trinta senón tamén porque eran vistos como os baluartes da identidade nacional. De feito, as características, necesidades e vías de desenvolvemento do sector agrario galego eran normalmente definidas en oposición ás do resto de España. É daquela comprensible que o PG tentase gañarse ás sociedades agrarias, e mesmo se pode afirmar que tiña moitos puntos en común cos chamados Partidos Agrarios doutras rexións europeas.

  14. Virtud en La República de Platón y El Príncipe de Maquiavelo

    OpenAIRE

    2014-01-01

    Desde el punto de vista de la ética de virtudes, el presente ensayo compara los filósofos-reyes de Platón con el príncipe de Maquiavelo. Primeramente, se define la ética de virtudes; seguidamente, se explica la manera en que se manifiesta la virtud en La República de Platón y El Príncipe de Maquiavelo. Finalmente, se valoran las semejanzas y diferencias entre ambos autores con respecto al concepto de virtud.

  15. Proteinopatías amiloides: desarrollo de un nuevo sistema modelo en microorganismos basado en RepA-WH1

    OpenAIRE

    Gasset Rosa, Fátima

    2012-01-01

    Las bases moleculares de la agregación de las proteínas amiloides son similares en todos los organismos, sean provenientes de microorganismos procariotas, hongos o metazoos. Muchas de estas proteínas poseen naturaleza priónica y son agentes causantes de enfermedades fatales (neurodegenerativas o sistémicas), cuyos mecanismos quedan todavía por esclarecer como previo paso hacia posibles terapias. Considerando estos presupuestos, el estudio de la amiloidosis de RepA-WH1, una proteína iniciadora...

  16. O surgimento da escola médica paulista no contexto brasileiro da Primeira República (1891 a 1930

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    Márcia Regina Silva Barros da

    2004-01-01

    Full Text Available Este trabajo intenta compreender el proceso de instauración de la enseñanza médica en São Paulo, Brasil, entre finales del siglo XIX y principios del siglo XX. Para tanto se discute los cambios que ocurrieron en el Estado de São Paulo en los comienzos del periodo de la República, en el contexto de la creación de nuevas instituciones médicas, tales como la Sociedade de Medicina e Cirurgia y el Serviço Sanitário, asi como surgimiento de varias revistas de la area.

  17. Experiencias de colaboradores tuneros en la República Democrática de Timor-Leste

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    Juana Magdalena Castro García

    2014-08-01

    Full Text Available En la presente comunicación breve se relatan las experiencias de una enfermera que se desempeñó profesionalmente en la asistencia médica y la docencia en la República Democrática de Timor Leste. A través de las vivencias compartidas se ponen de manifiesto los valores humanos que caracterizan al personal de la salud cubana, entre ellos: el humanismo, la responsabilidad, la laboriosidad y la solidaridad, características que muestran un ejemplo del papel de la mujer cubana en la Revolución

  18. Variedades de vegetales y de hongos existentes en la República Argentina y poseedoras de principios psicoactivos /

    OpenAIRE

    Acosta, Carlos Alberto

    2009-01-01

    Tesis [Maestría] -- Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Salud Pública En este trabajo se ha recopilado información correspondiente a 25 géneros, 34 especies de vegetales y 4 géneros ,4 especies de hongos que pueden ser encontrados en el espacio territorial de la República Argentina. Todos estos organismos poseen principios psicoactivos. Haciéndose referencia a la forma que se utilizan como fuente alternativa de sustancias psicoactivas y/o a su potencia...

  19. Acoso laboral: ¿Cómo intervenir? : Una mirada desde la Universidad de la República del Uruguay

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    Menéndez, Manuel; Cánepa, Elisa

    2014-01-01

    En el año 2010 la Universidad de la República del Uruguay, la principal universidad del país, que es pública y cogobernada, creó un Programa de Salud Mental (PSM) para abordar las problemáticas de salud mental de sus estudiantes y trabajadores. El PSM decidió abordar la problemática del acoso laboral debido a la gran demanda existente. Una investigación estadística realizada por el PSM sobre la Calidad de Vida de los trabajadores docentes y no docentes de la Universidad, publicada en el añ...

  20. Alguns ectoparasitas e protozoários em bovinos da República da Guiné-Bissau

    OpenAIRE

    ROSA, FERNANDA; Crespo, Maria Virgínia; Travassos Dias, J. A.

    1998-01-01

    Os autores assinalam a presença de algumas espécies de ixodídeos (Amblyomma variegatum, Boophilus annulatus, B. geigy e Hyalomma sp.) localizados em diferentes regiões do corpo de bovinos autóctones da República da Guiné-Bissau, colhidos entre Novembro de 1990 e Março de 1991. A pesquisa de protozoários, efectuada principalmente em esfregaços de sangue revelou a presença de Anaplasma marginale, Theileria mutans, Babesia bigemina e Sarcocystis sp. Não foram encontradas lesões relacionada...