The effect of temperature and time on the formation of amylose- lysophosphatidylcholine inclusion complexes

NARCIS (Netherlands)

Ahmadi-Abhari, S.; Woortman, A.J.J.; Oudhuis, A.A.C.M.; Hamer, R.J.; Loos, K.

2014-01-01

The formation of amylose inclusion complexes could help to decrease the susceptibility of starch granules against amylase digestion. We studied the formation of amyloselysophosphatidylcholine (LPC) inclusion complexes at temperatures at and below the gelatinization temperature of starch, using DSC,

The effect of temperature and time on the formation of amylose- lysophosphatidylcholine inclusion complexes

NARCIS (Netherlands)

Ahmadiabhari, Salomeh; Woortman, Albert J. J.; Oudhuis, A. A. C. M. (Lizette); Hamer, Rob J.; Loos, Katja

The formation of amylose inclusion complexes could help to decrease the susceptibility of starch granules against amylase digestion. We studied the formation of amylose-lysophosphatidylcholine (LPC) inclusion complexes at temperatures at and below the gelatinization temperature of starch, using DSC,

The effect of temperature and time on the formation of amylose–lysophosphatidylcholine inclusion complexes

NARCIS (Netherlands)

Ahmadi-Abhari, S.; Woortman, A.J.J.; Oudhuis, A.A.C.M.; Hamer, R.J.; Loos, K.

2014-01-01

The formation of amylose inclusion complexes could help to decrease the susceptibility of starch granules against amylase digestion. We studied the formation of amylose–lysophosphatidylcholine (LPC) inclusion complexes at temperatures at and below the gelatinization temperature of starch, using DSC,

Electron trapping during irradiation in reoxidized nitrided oxide

International Nuclear Information System (INIS)

Mallik, A.; Vasi, J.; Chandorkar, A.N.

1993-01-01

Isochronal detrapping experiments have been performed following irradiation under different gate biases in reoxidized nitrided oxide (RNO) MOS capacitors. These show electron trapping by the nitridation-induced electron traps at low oxide fields during irradiation. A difference in the detrapping behavior of trapped holes and electrons is observed, with trapped holes being detrapped at relatively lower temperatures compared to trapped electrons. Electron trapping shows a strong dependence on tile magnitude of the applied gate bias during irradiation but is independent of its polarity. Conventional oxide devices, as expected, do not show any electron trapping during irradiation by the native electron traps. Finally, a comparison of the isochronal detrapping behavior following irradiation and following avalanche injection of electrons has been made to estimate the extent of electron trapping. The results show that electron trapping by the nitridation-induced electron traps does not play the dominant role in improving radiation performance of RNO, though its contribution cannot be completely neglected for low oxide field irradiations

Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription.

Science.gov (United States)

Cifuentes-Muñoz, Nicolás; Branttie, Jean; Slaughter, Kerri Beth; Dutch, Rebecca Ellis

2017-12-15

Human metapneumovirus (HMPV) causes significant upper and lower respiratory disease in all age groups worldwide. The virus possesses a negative-sense single-stranded RNA genome of approximately 13.3 kb encapsidated by multiple copies of the nucleoprotein (N), giving rise to helical nucleocapsids. In addition, copies of the phosphoprotein (P) and the large RNA polymerase (L) decorate the viral nucleocapsids. After viral attachment, endocytosis, and fusion mediated by the viral glycoproteins, HMPV nucleocapsids are released into the cell cytoplasm. To visualize the subsequent steps of genome transcription and replication, a fluorescence in situ hybridization (FISH) protocol was established to detect different viral RNA subpopulations in infected cells. The FISH probes were specific for detection of HMPV positive-sense RNA (+RNA) and viral genomic RNA (vRNA). Time course analysis of human bronchial epithelial BEAS-2B cells infected with HMPV revealed the formation of inclusion bodies (IBs) from early times postinfection. HMPV IBs were shown to be cytoplasmic sites of active transcription and replication, with the translation of viral proteins being closely associated. Inclusion body formation was consistent with an actin-dependent coalescence of multiple early replicative sites. Time course quantitative reverse transcription-PCR analysis suggested that the coalescence of inclusion bodies is a strategy to efficiently replicate and transcribe the viral genome. These results provide a better understanding of the steps following HMPV entry and have important clinical implications. IMPORTANCE Human metapneumovirus (HMPV) is a recently discovered pathogen that affects human populations of all ages worldwide. Reinfections are common throughout life, but no vaccines or antiviral treatments are currently available. In this work, a spatiotemporal analysis of HMPV replication and transcription in bronchial epithelial cell-derived immortal cells was performed. HMPV was shown to

The Formation of COINS: Equity and Inclusion in SDSS

Science.gov (United States)

Schmidt, Sarah J.; Sanchez-Gallego, Jose Ramon; Chanover, Nancy J.; Holley-Bockelmann, Kelly; Lucatello, Sara; Aragon-Salamanca, Alfonso; Belfiore, Francesco; Cherinka, Brian; Feuillet, Diane; Jones, Amy; Masters, Karen; Simmons, Audrey; Ross, Ashley; Stassun, Keivan G.; Tayar, Jamie

2017-01-01

In the era of large surveys, collaborations like the Sloan Digital Sky Survey (SDSS) are becoming a new normal for many scientists, and collaboration policies and climate have a considerable affect on scientific careers. As such, it is essential that collaborations actively strive to include all scientists regardless of gender, gender identity, race, ethnicity, sexual orientation, disability, career stage, geographic location, economic background, social and cultural backgrounds, and all possible intersections thereof. We report on the formation and progress of the Committee On INclusiveness in the SDSS (COINS). COINS was formed to assess the SDSS-IV project and collaboration's climate and demographics, to recommend new policies or practices with regard to increasing inclusiveness, and to assist in the implementation of these new activities where necessary. We report on our current activities, which include ongoing support for the SDSS Research Experience for Undergraduates program, support for the SDSS Faculty and Student Teams initiative, administering and analyzing the SDSS demographic surveys, working towards collaboration meeting inclusiveness and accessibility, and adopting strategies for integrating and mentoring new members. We welcome input from SDSS members and non-members about how to work towards a more equitable and inclusive collaboration.

CRITERIA OF FORMATION OF SOCIAL-PEDAGOGICAL COMPETENCE OF FUTURE PRIMARY SCHOOL TEACHERS IN INCLUSIVE SECONDARY SCHOOL

Directory of Open Access Journals (Sweden)

Zoia Shevtsiv

2017-03-01

Full Text Available The article aims to justify the formation of criteria and indicators of social-pedagogical competence of the future teachers of primary school of inclusive comprehensive school and to determine its level of development. The objectives are to determine the status of the development problems of professional competence of teachers in inclusive education; essence and structural components of social-pedagogical competence of future primary school teacher of inclusive comprehensive school; criteria, indicators and levels of social-pedagogical competence of future primary school teacher of inclusive comprehensive schools. The education system in Ukraine is gradually transition to inclusive education. Inclusive comprehensive school is being created. It requires a highly qualified primary school teacher who co-teaches regulatory children and children with disability. The article is grounded the necessity of social-pedagogical competence of future teachers of primary school of inclusive comprehensive schools. The essence of social-pedagogical competence of future primary school teacher of inclusive comprehensive schools is defined. The structural components of social-pedagogical competence are characterized. Scientific papers on the issue of formation of competence of experts in various fields are analyzed. The pronunciation for selection and justification criteria and parameters of formation of professional competence is overviewed. The group of the criteria suggested by various scientists from the evaluation of the formation of professional competence of specialists in different fields is considered. The criteria and parameters of evaluating the levels of social-pedagogical competence of future teachers of primary school in inclusive comprehensive schools are selected on the base of the analysis of modern achievements of scientists. Future prospects of research is in developing of a method of diagnosing the levels of social-pedagogical competence of

Thermodynamics of inclusion formation and its influence on the corrosion behavior of Cu bearing duplex stainless steels

International Nuclear Information System (INIS)

Jeon, Soon-Hyeok; Kim, Soon-Tae; Lee, In-Sung; Park, Yong-Soo; Park, Joo-Hyun; Kim, Kwang-Tae; Kim, Ji-Soo

2011-01-01

To elucidate the thermodynamics of inclusion formation and its influence on the corrosion behavior of Cu bearing duplex stainless steels, potentiodynamic and potentiostatic polarization tests, a SEM-EDS analysis of inclusions, and thermodynamic calculations of the formation of inclusions were carried out. While the resistance to general corrosion of the noble copper contained alloy-1.5Cu in a deaerated 2 M H 2 SO 4 was higher than that of the alloy-BASE, the resistance to pitting corrosion of copper contained alloy-1.5Cu in a deaerated 0.5 N HCl + 1 N NaCl and 30 mass% NaCl was lower than that of the alloy-BASE due to an increase of interface areas between inclusions and matrix acting as preferential pit initiation sites. The thermodynamic calculation for the formation of Cr-containing oxide inclusions was in good agreement with the experimental results. (author)

Formation mechanism and control of MgO·Al2O3 inclusions in non-oriented silicon steel

Science.gov (United States)

Sun, Yan-hui; Zeng, Ya-nan; Xu, Rui; Cai, Kai-ke

2014-11-01

On the basis of the practical production of non-oriented silicon steel, the formation of MgO·Al2O3 inclusions was analyzed in the process of "basic oxygen furnace (BOF) → RH → compact strip production (CSP)". The thermodynamic and kinetic conditions of the formation of MgO·Al2O3 inclusions were discussed, and the behavior of slag entrapment in molten steel during RH refining was simulated by computational fluid dynamics (CFD) software. The results showed that the MgO/Al2O3 mass ratio was in the range from 0.005 to 0.017 and that MgO·Al2O3 inclusions were not observed before the RH refining process. In contrast, the MgO/Al2O3 mass ratio was in the range from 0.30 to 0.50, and the percentage of MgO·Al2O3 spinel inclusions reached 58.4% of the total inclusions after the RH refining process. The compositions of the slag were similar to those of the inclusions; furthermore, the critical velocity of slag entrapment was calculated to be 0.45 m·s-1 at an argon flow rate of 698 L·min-1, as simulated using CFD software. When the test steel was in equilibrium with the slag, [Mg] was 0.00024wt%-0.00028wt% and [Al]s was 0.31wt%-0.37wt%; these concentrations were theoretically calculated to fall within the MgO·Al2O3 formation zone, thereby leading to the formation of MgO·Al2O3 inclusions in the steel. Thus, the formation of MgO·Al2O3 inclusions would be inhibited by reducing the quantity of slag entrapment, controlling the roughing slag during casting, and controlling the composition of the slag and the MgO content in the ladle refractory.

Learner-Responsive Instructional Strategies for Adults in Accelerated Classroom Formats: Creating Inclusive Learning Environments

Science.gov (United States)

Gupta, Kalpana

2012-01-01

This study was focused on investigating inclusive learning environments in accelerated classroom formats. Three 8-week sections of an undergraduate course at Regis University were examined. Results from observations and surveys were analyzed to determine the effectiveness and consistency of 13 inclusive strategies derived from Wlodkowski and…

Formation of non-metallic inclusions and the possibility of their removal during ingot casting

OpenAIRE

Ragnarsson, Lars

2010-01-01

The present study was carried out to investigate the formation and evolution of non-metallic inclusions during ingot casting. Emphasize have been on understanding the types of inclusions formed and developed through the casting process and on the development of already existing inclusions carried over from the ladle during casting. Industrial experiments carried on at Uddeholm Tooling together with laboratory work and Computational Fluid Dynamics (CFD) simulations. Ingots of 5.8 tons have bee...

Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific

NARCIS (Netherlands)

Jansen, Anne H. P.; van Hal, Maurik; Op den Kelder, Ilse C.; Meier, Romy T.; de Ruiter, Anna-Aster; Schut, Menno H.; Smith, Donna L.; Grit, Corien; Brouwer, Nieske; Kamphuis, Willem; Boddeke, H. W. G. M.; den Dunnen, Wilfred F. A.; van Roon, Willeke M. C.; Bates, Gillian P.; Hol, Elly M.; Reits, Eric A.

2017-01-01

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder that is caused by a CAG expansion in the Huntingtin (HTT) gene, leading to HTT inclusion formation in the brain. The mutant huntingtin protein (mHTT) is ubiquitously expressed and therefore nuclear inclusions

Frequency of Nuclear Mutant Huntingtin Inclusion Formation in Neurons and Glia is Cell-Type-Specific

NARCIS (Netherlands)

Jansen, Anne H P; van Hal, Maurik; op den Kelder, Ilse C.; Meier, Romy T.; de Ruiter, Anna-Aster; Schut, Menno H.; Smith, Donna L.; Grit, Corien; Brouwer, Nieske; Kamphuis, Willem; Boddeke, H. W. G. M.; den Dunnen, Wilfred F. A.; van Roon, Willeke M. C.; Bates, Gillian P.; Hol, Elly M.; Reits, Eric A.

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder that is caused by a CAG expansion in the Huntingtin (HTT) gene, leading to HTT inclusion formation in the brain. The mutant huntingtin protein (mHTT) is ubiquitously expressed and therefore nuclear inclusions

Influence of crystallization conditions on formation and distribution of nonmetallic inclusions in steels

International Nuclear Information System (INIS)

Efimov, V.A.

1977-01-01

The processes were studied of the formation and the distribution of nonmetallic inclusions and the chemical inhomogeneity formation during the solidification of h steel. The variation of the character of oxides and sulfides across ingots was shown by considering st 25 and 20 Kh steels. To improve the distribution of inclusions and the stability of properties throughout the body of ingots, it is recommended to throughly deoxidize the metal, to raise the rate of solidification, to reduce the temperature gradient, to employ powder cooling agents, to use casting under a blanket of slag, to modify steel by active elements (r.e.e., Ca, Ba, Zr, B) which affect favourably the nature and the shape of the nonmetallic phase

Topotactic reduction and reoxidation of hexagonal RCu0.5Ti0.5O3 (R = Y, Eu-Lu) Phases

International Nuclear Information System (INIS)

Jiang, Peng; Berthelot, Romain; Li, Jun; Sleight, A.W.; Subramanian, M.A.

2013-01-01

Highlights: ► Topotactic reduction of hexagonal RCu 0.5 Ti 0.5 O 3 phases is performed. ► TGA and magnetism indicate a formula of RCu 0.5 Ti 0.5 O 2.78 for the reduced phase. ► Topotactic reoxidation occurs on heating these phases to 400 °C in air. - Abstract: Hexagonal AMO 2 and AMO 3 phases have the same basic structure, and intermediate compositions for this structure have been prepared by topotactic oxidation of AMO 2 phases such as RCuO 2 , where R is a trivalent rare earth cation. We now find that such intermediate phases can also be prepared by topotactic reduction of hexagonal RCu 0.5 Ti 0.5 O 3 (R = Y, Tb-Lu) phases. Our TGA and magnetic susceptibility studies indicate a formula of RCu 0.5 Ti 0.5 O 2.78 for these reduced phases. Topotactic reoxidation occurs on heating these phases to 400 °C in air

High-Temperature Confocal Laser Scanning Microscopy Studies of Ferrite Formation in Inclusion-Engineered Steels: A Review

Science.gov (United States)

Mu, Wangzhong; Hedström, Peter; Shibata, Hiroyuki; Jönsson, Pär G.; Nakajima, Keiji

2018-05-01

The concepts of oxide metallurgy and inclusion engineering can be utilized to improve the properties of low-alloy steels. These concepts aim at controlling the formation of intragranular ferrite (IGF), often a desirable microstructure providing good mechanical properties without the need for expensive alloying elements. IGF formation is stimulated to occur at non-metallic inclusions and form an arrangement of fine, interlocking ferrite grains. A method that has contributed significantly to investigations in this field lately is high-temperature confocal laser scanning microscopy (HT-CLSM). HT-CLSM is suited for in situ studies of inclusion behavior in liquid steel and phase transformations in solid-state steel, where in particular, displacive phase transformations can be studied, since they provide sufficient topographic contrast. The purpose of the present report is to provide a brief review of the state of the art of HT-CLSM and its application for in situ observations of ferrite formation in inclusion-engineered steels. The scientific literature in this field is surveyed and supplemented by new work to reveal the capability of HT-CLSM as well as to discuss the effect of factors such as cooling rate and parent grain size on IGF formation and growth kinetics. The report concludes with an outlook on the opportunities and challenges of HT-CLSM for applications in oxide metallurgy.

A Study on N{sub 2}O Direct Oxidation Process with Re-oxidation Annealing for the Improvement of Interface Properties in 4H-SiC MOS Capacitor

Energy Technology Data Exchange (ETDEWEB)

Cho, Doohyung; Park, Kunsik; Yoo, Seongwook; Kim, Sanggi; Lee, Jinhwan; Kim, Kwangsoo [Electronics and Telecommunications Research Institute (ETRI), Daejeon (Korea, Republic of)

2017-08-15

The effect of N{sub 2}O direct oxidation processes with re-oxidation on SiC/SiO{sub 2} interface characteristics has been investigated. With different oxidation and post oxidation annealing (POA) processes, the flat-band voltage, effective dielectric charge density, and interface trap density are obtained from the capacitance-voltage curves. For the proposed N{sub 2}O direct oxidation processes with re-oxidation, oxides were grown in N{sub 2}O ambient, diluted in high-purity N{sub 2} to 10% concentration, for 5 h at 1230 ℃. After the growth, some samples were annealed additionally at 1200 ℃ in O{sub 2} or H{sub 2}O for 20 min. N{sub 2}O direct oxidation with re-oxidation processes was confirmed that SiC/SiO{sub 2} interface properties and dielectric stability have better performance than with other conventional oxidation processes. This oxidation technique is expected to improve gate dielectric stability for application to SiC MOS devices; in particular, it can be used to obtain high-quality SiC/SiO{sub 2} interface properties.

Kinetics of inclusion body formation and its correlation with the characteristics of protein aggregates in Escherichia coli.

Directory of Open Access Journals (Sweden)

Arun K Upadhyay

Full Text Available The objective of the research was to understand the structural determinants governing protein aggregation into inclusion bodies during expression of recombinant proteins in Escherichia coli. Recombinant human growth hormone (hGH and asparaginase were expressed as inclusion bodies in E.coli and the kinetics of aggregate formation was analyzed in details. Asparaginase inclusion bodies were of smaller size (200 nm and the size of the aggregates did not increase with induction time. In contrast, the seeding and growth behavior of hGH inclusion bodies were found to be sequential, kinetically stable and the aggregate size increased from 200 to 800 nm with induction time. Human growth hormone inclusion bodies showed higher resistance to denaturants and proteinase K degradation in comparison to those of asparaginase inclusion bodies. Asparaginase inclusion bodies were completely solubilized at 2-3 M urea concentration and could be refolded into active protein, whereas 7 M urea was required for complete solubilization of hGH inclusion bodies. Both hGH and asparaginase inclusion bodies showed binding with amyloid specific dyes. In spite of its low β-sheet content, binding with dyes was more prominent in case of hGH inclusion bodies than that of asparaginase. Arrangements of protein molecules present in the surface as well as in the core of inclusion bodies were similar. Hydrophobic interactions between partially folded amphiphillic and hydrophobic alpha-helices were found to be one of the main determinants of hGH inclusion body formation. Aggregation behavior of the protein molecules decides the nature and properties of inclusion bodies.

Kinetics of Inclusion Body Formation and Its Correlation with the Characteristics of Protein Aggregates in Escherichia coli

Science.gov (United States)

Upadhyay, Arun K.; Murmu, Aruna; Singh, Anupam; Panda, Amulya K.

2012-01-01

The objective of the research was to understand the structural determinants governing protein aggregation into inclusion bodies during expression of recombinant proteins in Escherichia coli. Recombinant human growth hormone (hGH) and asparaginase were expressed as inclusion bodies in E.coli and the kinetics of aggregate formation was analyzed in details. Asparaginase inclusion bodies were of smaller size (200 nm) and the size of the aggregates did not increase with induction time. In contrast, the seeding and growth behavior of hGH inclusion bodies were found to be sequential, kinetically stable and the aggregate size increased from 200 to 800 nm with induction time. Human growth hormone inclusion bodies showed higher resistance to denaturants and proteinase K degradation in comparison to those of asparaginase inclusion bodies. Asparaginase inclusion bodies were completely solubilized at 2–3 M urea concentration and could be refolded into active protein, whereas 7 M urea was required for complete solubilization of hGH inclusion bodies. Both hGH and asparaginase inclusion bodies showed binding with amyloid specific dyes. In spite of its low β-sheet content, binding with dyes was more prominent in case of hGH inclusion bodies than that of asparaginase. Arrangements of protein molecules present in the surface as well as in the core of inclusion bodies were similar. Hydrophobic interactions between partially folded amphiphillic and hydrophobic alpha-helices were found to be one of the main determinants of hGH inclusion body formation. Aggregation behavior of the protein molecules decides the nature and properties of inclusion bodies. PMID:22479486

Reduction and re-oxidation of Cu/Al{sub 2}O{sub 3} catalysts investigated with quick-scanning XANES and EXAFS

Energy Technology Data Exchange (ETDEWEB)

Stoetzel, J; Luetzenkirchen-Hecht, D; Frahm, R [Department of Physics, University of Wuppertal, Gaussstr. 20, D-42097 Wuppertal (Germany); Kimmerle, B; Baiker, A [Department of Chemistry and Applied Biosciences, ETH Zuerich, CH-8093 Zuerich (Switzerland); Nachtegaal, M [Paul Scherrer Institut, CH-5232 Villigen (Switzerland); Beier, M J; Grunwaldt, J-D, E-mail: j.stoetzel@uni-wuppertal.d, E-mail: jdg@kt.dtu.d [Department of Chemical and Biochemical Engineering, Technical University of Denmark, Building 229, DK-2800 Kgs. Lyngby (Denmark)

2009-11-15

In the present study the structure of copper catalysts on alumina support were investigated in situ and time resolved during reduction and re-oxidation at different temperatures with the quick-scanning EXAFS (QEXAFS) technique. Different impregnation times (2 min and 90 min) were chosen for the preparation which resulted in different copper species that show a strong variation in the reduction/re-oxidation behaviour. These dynamic changes as well as possible intermediate phases during the gas atmospheres changes were followed with up to 20 EXAFS spectra per second at the copper K-edge covering an energy range of 450 eV. The high time resolution provided new insights into the dynamics of the catalysts e.g. revealing Cu(I) as intermediate state during re-oxidation. Latest advances in the data acquisition hardware are leading to an improved data quality of spectra collected at the SuperXAS beamline. Thus, not only accurate analysis of the catalysts via XANES but also by EXAFS was possible. This is also due to the recent upgrade to monitor the Bragg angle directly with an encoder during the experiments.

Reversibility of neurofilamentous inclusion formation following repeated sublethal intracisternal inoculums of AlCl3 in New Zealand white rabbits.

Science.gov (United States)

Strong, M J; Gaytan-Garcia, S; Jakowec, D M

1995-01-01

In this report, we describe the clinical, topographical and immunohistochemical characteristics of neurofilament (NF) inclusion formation induced by the intracisternal inoculation of young adult New Zealand white rabbits at 28-day intervals with 100 micrograms AlCl3 over the course of 267 days. The ability to recover following cessation of aluminum exposure has also been assessed. The extent of neurofilamentous inclusion formation was proportionate to the cumulative amount of AlCl3 inoculated and initially consisted of fusiform axonal distention in the ventral spinal cord at day 51 following the initial inoculum. Spinal motor neuron perikaryal inclusions and discrete axonal spheroids were observed at day 107 and supraspinal neurofilamentous pathology by day 156. Perikaryal inclusions were immunoreactive to antibodies recognizing both poorly phosphorylated (SMI 32) and more highly phosphorylated high molecular weight NF (NFH). In contrast, axonal spheroids were intensely immunoreactive at all stages with antibodies recognizing highly phosphorylated NFH and an age-dependent NFH phosphorylation state (SMI 34) with only faint SMI 32 immunoreactivity. Immunoreactivity to an antibody recognizing ubiquitin-protein conjugates did not appear until day 156, whereas inclusions were not immunoreactive to antibodies recognizing either phosphatase-dependent or -independent microtubule-associated protein tau at any stage. Upon withdrawal from further AlCl3 exposure after intervals of 51, 107 or 156 days following the initial inoculum, clinical recovery ensued in all rabbits. In all but the most severely affected rabbits, perikaryal neurofilamentous inclusions resolved. However, axonal spheroids continued to be prominent. These studies demonstrate that the repetitive intracisternal inoculation of AlCl3 in New Zealand white rabbits induces a reversible process of neurofilamentous inclusion formation that preferentially affects motor neurons, and in which recovery will occur in

Topotactic reduction and reoxidation of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} (R = Y, Eu-Lu) Phases

Energy Technology Data Exchange (ETDEWEB)

Jiang, Peng, E-mail: jiangp@onid.orst.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Berthelot, Romain, E-mail: berthelot.rom@gmail.com [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Li, Jun, E-mail: jli100@yahoo.com [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Sleight, A.W., E-mail: arthur.sleight@oregonstate.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Subramanian, M.A., E-mail: mas.subramanian@oregonstate.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States)

2013-06-01

Highlights: ► Topotactic reduction of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} phases is performed. ► TGA and magnetism indicate a formula of RCu{sub 0.5}Ti{sub 0.5}O{sub 2.78} for the reduced phase. ► Topotactic reoxidation occurs on heating these phases to 400 °C in air. - Abstract: Hexagonal AMO{sub 2} and AMO{sub 3} phases have the same basic structure, and intermediate compositions for this structure have been prepared by topotactic oxidation of AMO{sub 2} phases such as RCuO{sub 2}, where R is a trivalent rare earth cation. We now find that such intermediate phases can also be prepared by topotactic reduction of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} (R = Y, Tb-Lu) phases. Our TGA and magnetic susceptibility studies indicate a formula of RCu{sub 0.5}Ti{sub 0.5}O{sub 2.78} for these reduced phases. Topotactic reoxidation occurs on heating these phases to 400 °C in air.

SOCIO-CULTURAL COMPETENCE FORMATION BY MEANS OF TRANSLATION IN THE CONDITIONS OF INCLUSIVE EDUCATION

Directory of Open Access Journals (Sweden)

Kateryna Shapochka

2016-12-01

Full Text Available The article is devoted to the problem of socio-cultural competence formation by means of translation / interpretation and the necessity of foreign language communicative competence formation in the process of inclusive education. The question of training of young generation for life in a multi-ethnic and multicultural society, forming skills of communication and cooperation with people of different nationalities, the foreign language learning, the formation of the communicative and socio-cultural competence is one of the main tasks of modern school to meet educational needs persons with disabilities. Today’s realities require that students with special educational needs should study a foreign language and use it in the process of learning. In turn, the use of translation in the process of learning a foreign language helps students to get new skills, to form general and specific competences, including socio-cultural competence, which promotes socialization of children with special needs, and integrating them into a comprehensive system of Ukraine. The article raises the problem of modernization of the educational system. It was established that the formation of socio-cultural competence by means of written translation is done by means of a system of exercises. Based on this system, subsystems, groups and types of exercises their systems can be developed in accordance with human activity, objectives and learning environment. It shows that the development of an inclusive approach to learning demands new solutions towards learning a foreign language at different levels of education.

Factors Controlling In Situ Uranium and Technetium Bio-Reduction and Reoxidation at the NABIR Field Research Center

International Nuclear Information System (INIS)

Istok, Jonathan; Krumholz, L; McKinley, J.; Gu, B.

2004-01-01

Summary of Recent Field Testing: Extensive in situ (in ground) field testing using the push-pull method has demonstrated that indigenous microorganisms in the shallow ( ∼ 20 mM. Field data and laboratory studies suggest that U(IV) is likely oxidized by Fe(III) minerals produced by enzymatic Fe(II) oxidation or by Fe(II) oxidation by nitrite. U(IV) reoxidation rates (10-3 to 10-2 uM/hr) were somewhat larger than U(VI) reduction rates indicating that sustained nitrate removal will be necessary to maintain the stability of U(IV) in this environment

Computer Simulation of Microsegregation of Sulphur and Manganese and Formation of MnS Inclusions while Casting Rail Steel

Directory of Open Access Journals (Sweden)

Kalisz D.

2016-12-01

Full Text Available The quality of rail steel is conditioned by its high mechanic qualities, which greatly depend on the presence of undesired nonmetallic inclusions. The paper is devoted to the segregation of components, mainly sulphur, and the formation of manganese sulphide in the process of steel solidification, at the casting rate of 100 and 500 K/min. Sulphur is a steel component which disadvantageously influences its numerous parameters. The oxide-sulphide and sulphide precipitations cause cracks and lower the strength of the material. This phenomenon was modeled with the use of author’s computer program based on Matsumiya interdendritic microsegregation model. The main assumptions of this model and thermodynamic conditions of inclusion formation during casting of steel are discussed in this paper. Two cases were analyzed: in the first one the MnS was assumed to form a pure and constant compound, whereas in the other one the manganese sulfide was precipitated as a component of a liquid oxide solution, and its activity was lower than unity. The final conclusion is that chemical composition of steel is the major parameter deciding about the formation of MnS inclusions.

Effect of re-oxidation annealing process on the SiO2/SiC interface characteristics

International Nuclear Information System (INIS)

Yan Hongli; Jia Renxu; Tang Xiaoyan; Song Qingwen; Zhang Yuming

2014-01-01

The effect of the different re-oxidation annealing (ROA) processes on the SiO 2 /SiC interface characteristics has been investigated. With different annealing processes, the flat band voltage, effective dielectric charge density and interface trap density are obtained from the capacitance—voltage curves. It is found that the lowest interface trap density is obtained by the wet-oxidation annealing process at 1050 °C for 30 min, while a large number of effective dielectric charges are generated. The components at the SiO 2 /SiC interface are analyzed by X-ray photoelectron spectroscopy (XPS) testing. It is found that the effective dielectric charges are generated due to the existence of the C and H atoms in the wet-oxidation annealing process. (semiconductor technology)

Reduction And Sequestration Of Pertechnetate To Technetium Dioxide And Protection From Reoxidation

International Nuclear Information System (INIS)

Duncan, J. B.; Johnson, J. M.; Moore, R. C.; Hagerty, K.; Rhodes, R. N.; Huber, H. J.; Moore, W. P.

2012-01-01

This effort is part of the technetium management initiative and provides data for the handling and disposition of technetium. To that end, the objective of this effort was to challenge tin(lI)apatite (Sn(II)apatite) against double-shell tank 241-AN-105 simulant spiked with pertechnetate (TcO 4 ). The Sn(II)apatite used in this effort was synthesized on site using a recipe developed at and provided by Sandia National Laboratories; the synthesis provides a high quality product while requiring minimal laboratory effort. The Sn(ll)apatite reduces pertechnetate from the mobile +7 oxidation state to the non-mobile +4 oxidation state. It also sequesters the technetium and does not allow for re-oxidization to the mobile +7 state under acidic or oxygenated conditions within the tested period of time (6 weeks). Previous work indicated that the Sn(II) apatite can achieve an ANSI leachability index in Cast Stone of 12.8. The technetium distribution coefficient for Sn(lI)apatite exhibited a direct correlation with the pH of the technetium-spiked simulant media

The influence of dissolved H2O content in supercritical carbon dioxide to the inclusion complexes formation of ketoprofen/β-cyclodextrin

Science.gov (United States)

Goenawan, Joshua; Trisanti, P. N.; Sumarno

2015-12-01

This work studies the relation between dissolved H2O content in supercritical carbon dioxide (SC-CO2) with the formation of ketoprofen (KP)/β-cyclodextrin(CD) inclusion complexes. The process involves a physical mixture of these two compounds into contact with the supercritical carbon dioxide which had been previously saturated with H2O over a certain duration. The pressure used for saturation process is 130 bar and saturation temperature was ranged between 30 °C to 50 °C. The inclusion process was achieved by keeping it for 2 hours at 160 bar and 200 bar with inclusion temperature of 50 °C. The results enable us to suggest explanations for the inclusion formation. The inclusion complexes can be formed by contacting the dissolved H2O in SC-CO2 to the physical mixture of KP and CD. An increase in the temperature of saturation process resulted in an increase of dissolved H2O content in the supercritical carbon dioxide. The increasing levels of this water soluble resulted an increase in the inclusion complexes that has been formed. The formation of inclusion complexes includes the water molecules enhancing the emptying of the CD cavities and being replaced by KP, towards a more stable energy state. The drug release used for analyzing the dissolution rate of the KP/CD complexes. The results vary from 79,85% to 99,98% after 45 minutes which is above the rate that has been assigned by Farmakope Indonesia at 70% dissolution rate for KP. The use of SC-CO2 offers a new methods for increasing the rate of dissolution of drugs that are hydrophobic such as KP. CO2 used as a supercritical fluid because of its relatively low cost, easily obtainable supercritical conditions, and lack of toxicity. The material samples were characterized by DSC and Spectrophotometer UV-vis technique.

Financial Inclusion, Entry Barriers, and Entrepreneurship: Evidence from China

Directory of Open Access Journals (Sweden)

Zhaobin Fan

2017-02-01

Full Text Available This paper aims at investigating the relationship between financial inclusion and the formation of entrepreneurs, both theoretically and empirically. We first construct a theoretical model to examine how the development of financial inclusion affects the formation of entrepreneurs. The model suggests that the development of financial inclusion can mitigate credit constraints on entrepreneurial activities by reducing information asymmetry in financial transactions, and in addition this effect is greater in industries with lower barriers to entry. Then, using data from 31 provinces and 19 industries in China during the period 2005–2014, we test the impact of financial inclusion on the formation of entrepreneurs. The estimation results confirm the positive effect of financial inclusion development on the formation of entrepreneurs, and indicate that this effect is heterogeneous across industries. Moreover, the development of financial inclusion is often beneficial to the formations of entrepreneurs in sectors with lower entry barriers.

Reduction and reoxidation of cobalt Fischer-Tropsch catalysts

Energy Technology Data Exchange (ETDEWEB)

Hilmen, Anne-Mette

1996-12-31

The Fischer-Tropsch synthesis involves the hydrogenation of carbon monoxide to produce mainly hydrocarbons, water and carbon dioxide, but also alcohols, aldehydes and acids are formed. The distribution of these products is determined by the choice of catalyst and synthesis conditions. This thesis studies the reduction and reoxidation of 17%Co/Al{sub 2}O{sub 3} and 17%Co-1%Re/Al{sub 2}O{sub 3} by means of several characterization techniques. The effect of small amounts of Re on the reduction properties of Al{sub 2}O{sub 3}-supported Co catalysts has been studied by temperature-programmed reduction (TPR). An intimate mixture of CoAl{sub 2}O{sub 3} and Re/Al{sub 2}O{sub 3} catalysts showed a promoting effect of Re similar to that for co impregnated CoRe/Al{sub 2}O{sub 3}. A loose mixture of Co/Al{sub 2}O{sub 3} + Re/Al{sub 2}O{sub 3} did not show any effect of Re on the reduction of Co. But a promoting effect was observed if the mixture had been pre-treated with Ar saturated with water before the TPR. It is suggested that Re promotes the reduction of Co oxide by hydrogen spillover. It is shown that a high temperature TPK peak at 1200K assigned to Co aluminate is mainly caused by the diffusion of Co ions during the TPR and not during calcination. The Co particle size measured by x-ray diffraction on oxidized catalysts decreased compared to the particle size on the calcined catalysts, while the dispersion measured by volumetric chemisorption decreased somewhat after the oxidation-reduction treatment. The role of water in the deactivation of Co/Al{sub 2}O{sub 3} and CoRe/Al{sub 2}O{sub 3} Fischer-Tropsch catalysts has been extensively studied. There were significant differences in the reducibility of the phases formed for the two catalysts during exposure to H{sub 2}O/He. 113 refs., 76 figs., 18 tabs.

Immobilization of 99-Technetium (VII) by Fe(II)-Goethite and Limited Reoxidation

Energy Technology Data Exchange (ETDEWEB)

W Um; H Chang; J Icenhower; W Lukens; R Serne; N Qafoku; J Westsik Jr.; E Buck; S Smith

2011-12-31

During the nuclear waste vitrification process volatilized {sup 99}Tc will be trapped by melter off-gas scrubbers and then washed out into caustic solutions, and plans are currently being contemplated for the disposal of such secondary waste. Solutions containing pertechnetate [{sup 99}Tc(VII)O{sub 4}{sup -}] were mixed with precipitating goethite and dissolved Fe(II) to determine if an iron (oxy)hydroxide-based waste form can reduce Tc(VII) and isolate Tc(IV) from oxygen. The results of these experiments demonstrate that Fe(II) with goethite efficiently catalyzes the reduction of technetium in deionized water and complex solutions that mimic the chemical composition of caustic waste scrubber media. Identification of the phases, goethite + magnetite, was performed using XRD, SEM and TEM methods. Analyses of the Tc-bearing solid products by XAFS indicate that all of the Tc(VII) was reduced to Tc(IV) and that the latter is incorporated into goethite or magnetite as octahedral Tc(IV). Batch dissolution experiments, conducted under ambient oxidizing conditions for more than 180 days, demonstrated a very limited release of Tc to solution (2-7 {micro}g Tc/g solid). Incorporation of Tc(IV) into the goethite lattice thus provides significant advantages for limiting reoxidation and curtailing release of Tc disposed in nuclear waste repositories.

Immobilization of 99-Technetium (VII) by Fe(II)-Goethite and Limited Reoxidation

International Nuclear Information System (INIS)

Um, Wooyong; Chang, Hyun-Shik; Icenhower, Jonathan P.; Lukens, Wayne W.; Serne, R. Jeffrey; Qafoku, Nikolla; Westsik, Joseph H.; Buck, Edgar C.; Smith, Steven C.

2011-01-01

Synthesized goethite was successfully used with addition of Fe(II) to sequester Tc present in both deionized water and simulated off-gas scrubber waste solutions. Pertechnetate concentration in solution decreased immediately when the pH was raised above 7 by addition of sodium hydroxide. Removal of Tc(VII) from solution occurred most likely as a result of heterogeneous surface-catalyzed reduction to Tc(IV) and subsequent co-precipitation onto the goethite. The final Tc-bearing solid was identified as goethite-dominated Fe(III)-(oxy)hydroxide based on XRD analysis, confirming the widespread observation of its characteristic acicular habit by TEM/SEM images. Analysis of the solid precipitate by XAFS showed that the dominant oxidation state of Tc was Tc(IV) and was in octahedral coordination with Tc-O, Fe-O, and Tc-Fe bond distances that are consistent with direct substitution of Tc for Fe in the goethite structure. In some experiments the final Tc-goethite product was subsequently armored with additional layers of freshly precipitated goethite. Successful incorporation of Tc(IV) within the goethite mineral lattice and subsequent goethite armoring can limit re-oxidation of Tc(IV) and its subsequent release from Tc-goethite waste forms, even when the final product is placed in oxidizing environments that typify shallow waste burial facilities.

Preliminary report on fluid inclusions from halites in the Castile and lower Salado formations of the Delaware Basin, southeastern New Mexico

International Nuclear Information System (INIS)

Stein, C.L.

1985-09-01

A suite of samples composed primarily of halite from the upper Castile and lower Salado Formations of the Permian Basin was selected from Waste Isolation Pilot Plant (WIPP) core for a reconnaissance study of fluid inclusions. Volume percent of these trapped fluids averaged 0.7% to 1%. Freezing-point depressions varied widely and appeared to be unrelated to fluid-inclusion type, to sedimentary facies, or to stratigraphic depth. However, because very low freezing points were usually associated with anhydrite, a relation may exist between freezing-point data and lithology. Dissolved sulfate values were constant through the Castile, then decreased markedly with lesser depth in the lower Salado. This trend correlates very well with observed mineralogy and is consistent with an interpretation of the occurrence of secondary polyhalite as a result of gypsum or anhydrite alteration with simultaneous consumption of dissolved sulfate from the coexisting fluids. Together with the abundance and distribution of fluid inclusions in primary or ''hopper'' crystal structures, this evidence suggests that inclusions seen in these halites did not migrate any significant geographical distance since their formation. 28 refs., 17 figs., 2 tabs

Evidence for distillation in the formation of HAL and related hibonite inclusions. [from Allende, Dhajala, and Murchison chondrites

Science.gov (United States)

Ireland, Trevor R.; Zinner, Ernst K.; Fahey, Albert J.; Esat, Tezer M.

1992-01-01

New Ca- and Ti-isotopic analyses of DH-H1, 7-404, and 7-971, and Mg-isotopic analyses on DH-H1 and 7-404 are reported. O-isotopic analyses of HAL, 7-404, 7-971, and a variety of other refractory inclusions from Murchison were made in order to establish the presence or absence of FUN O-isotopic systematics. A higonite-rich residue produced by the evaporation of kaersutite was analyzed for its trace-element and isotopic abundances to see if any of the characteristics of FUN hibonite inclusions can be produced by distillation in the laboratory. These data are then used to evaluate for all four inclusions the HAL-type formation models originally proposed by Allen et al. (1980) and Lee et al. (1980). The four inclusions were found to have very similar chemical and isotopic features. All are characterized by large Ce depletions and very low Mg, Ti, and V concentrations compared to other meteoritic hibonites. All four inclusions have delta(C-48) within error of -5 per mil. Ca-, Ti-, and O-isotopic compositions are fractionated with enrichments of the heavy isotopes, and the Ti-isotopic mass fractionation is inversely correlated with Ti concentration. It is concluded that the inclusions formed primarily as distillation residues in accord with the early conclusions.

Role for chlamydial inclusion membrane proteins in inclusion membrane structure and biogenesis.

Directory of Open Access Journals (Sweden)

Jeffrey Mital

Full Text Available The chlamydial inclusion membrane is extensively modified by the insertion of type III secreted effector proteins. These inclusion membrane proteins (Incs are exposed to the cytosol and share a common structural feature of a long, bi-lobed hydrophobic domain but little or no primary amino acid sequence similarity. Based upon secondary structural predictions, over 50 putative inclusion membrane proteins have been identified in Chlamydia trachomatis. Only a limited number of biological functions have been defined and these are not shared between chlamydial species. Here we have ectopically expressed several C. trachomatis Incs in HeLa cells and find that they induce the formation of morphologically distinct membranous vesicular compartments. Formation of these vesicles requires the bi-lobed hydrophobic domain as a minimum. No markers for various cellular organelles were observed in association with these vesicles. Lipid probes were incorporated by the Inc-induced vesicles although the lipids incorporated were dependent upon the specific Inc expressed. Co-expression of Inc pairs indicated that some colocalized in the same vesicle, others partially overlapped, and others did not associate at all. Overall, it appears that Incs may have an intrinsic ability to induce membrane formation and that individual Incs can induce membranous structures with unique properties.

Starch-lipid inclusion complexes for aerogel formation

Science.gov (United States)

Recently we reported that aqueous slurries of starch can be excess steam jet-cooked and blended with aqueous solutions of fatty acid salts to produce inclusion complexes between amylose and the fatty acid salt. These complexes can be simply prepared on large scale using commercially available steam ...

Characterization of inclusions in terrestrial impact formed zircon: Constraining the formation conditions of Hadean zircon from Jack Hills, Western Australia

Science.gov (United States)

Faltys, J. P.; Wielicki, M. M.; Sizemore, T. M.

2017-12-01

Due to the discovery and subsequent geochemical analysis of Hadean terrestrial material (e.g. detrital zircon from Jack Hills, Western Australia), a dramatic paradigm shift has occurred in the hypothesized near surface conditions of the first 500 million years of Earth's evolution. From a hellish setting riddled with impactors and not fit for life to a much milder environment that may have been uniquely suitable for the origin of life. Geochemical analyses of these ancient materials have been used to suggest the presence of water at or near the surface as well as the existence of continental crust during the Hadean, both of which have been suggested as necessary for the origin of life. However, the intensity of extraterrestrial bombardment during the Hadean and the effects of such events on the origin of life remains poorly understood. Clearly, as evidenced by Phanerozoic impact events, extraterrestrial impactors have the potential to dramatically effect the environment, particularly the biosphere. Early Earth likely experienced multiple large impact events, as evidenced by the lunar record, however whether those impacts were sufficient to frustrate the origin of life remains an open question. Although multiple lines of evidence, including the inclusion population, suggest the formation of Hadean zircon from Jack Hills as crystallizing in an under-thrust environment from S-type magmas, a recent study has suggested their formation in an impact melt environment analogous to a portion of the Sudbury Igneous Complex at the Sudbury impact structure. To determine between these two formation scenarios we have under-taken an inclusion study of terrestrial impact formed zircon from four of the largest terrestrial impact structures (Sudbury, Canada; Manicouagan, Canada; Vredefort, South Africa; Morokweng, South Africa), to compare to the vast inclusion dataset that exists for Jack Hills zircon. Preliminary data suggests a different inclusion population, from Hadean zircon

Formation mechanism of channel segregation in carbon steels by inclusion flotation: X-ray microtomography characterization and multi-phase flow modeling

International Nuclear Information System (INIS)

Cao, Yan Fei; Chen, Yun; Li, Dian Zhong

2016-01-01

Recent experimental dissections of steel ingots and multi-scale simulations have led to the discovery of a potential driving force for channel segregation: the flotation of oxide-based inclusion (D. Li et al., Nat. Commun. 5:5572 (2014)). Further experimental analysis and numerical modeling are necessary to clarify this mechanism in detail. In this work, the inclusions in a carbon steel ingot that exhibits severe channel segregations were characterized by the 3D X-ray microtomography, which revealed a significant enrichment and growth of inclusions in the channels. Based on above microtomography characterization, a 2D macrosegregation model encompassing the inclusion flotation was established. In the model, the motions of solid inclusions and liquid were described using the multi-phase flow scheme within the Euler-Lagrange framework. The benchmark simulations showed that sufficient inclusion populations with appropriate sizes are capable of altering the local flow patterns and destabilize the mushy zone, initiating the subsequent channel segregation. The continuous interplay between melt convection, inclusion flotation and solidification eventually causes the formation of macroscale channel. The predicted sizes and volume fraction of inclusions that are able to trigger the channel segregation effectively are consistent with the data obtained via microtomography characterization. The macrosegregation model was then applied to predict the channel segregations in an industrial carbon steel ingot. A rather good agreement of A-segregates was achieved between the simulation and the dissected ingot.

An Amino Acid of Human Parainfluenza Virus Type 3 Nucleoprotein Is Critical for Template Function and Cytoplasmic Inclusion Body Formation

Science.gov (United States)

Zhang, Shengwei; Chen, Longyun; Zhang, Guangyuan; Yan, Qin; Yang, Xiaodan; Ding, Binbin; Tang, Qiaopeng; Sun, Shengjun; Hu, Zhulong

2013-01-01

The nucleoprotein (N) and phosphoprotein (P) interaction of nonsegmented negative-strand RNA viruses is essential for viral replication; this includes N0-P (N0, free of RNA) interaction and the interaction of N-RNA with P. The precise site(s) within N that mediates the N-P interaction and the detailed regulating mechanism, however, are less clear. Using a human parainfluenza virus type 3 (HPIV3) minigenome assay, we found that an N mutant (NL478A) did not support reporter gene expression. Using in vivo and in vitro coimmunoprecipitation, we found that NL478A maintains the ability to form NL478A0-P, to self-assemble, and to form NL478A-RNA but that NL478A-RNA does not interact with P. Using an immunofluorescence assay, we found that N-P interaction provides the minimal requirement for the formation of cytoplasmic inclusion bodies, which contain viral RNA, N, P, and polymerase in HPIV3-infected cells. NL478A was unable to form inclusion bodies when coexpressed with P, but the presence of N rescued the ability of NL478A to form inclusion bodies and the transcriptional function of NL478A, thereby suggesting that hetero-oligomers formed by N and NL478A are functional and competent to form inclusion bodies. Furthermore, we found that NL478A is also defective in virus growth. To our knowledge, we are the first to use a paramyxovirus to identify a precise amino acid within N that is critical for N-RNA and P interaction but not for N0-P interaction for the formation of inclusion bodies, which appear to be bona fide sites of RNA synthesis. PMID:24027324

Fluid inclusions and PVTX modelling: examples from the Garn Formation in well 6507/2-2, Haltenbanken, Mid-Norway

Energy Technology Data Exchange (ETDEWEB)

Teinturier, S.; Pironon, J. [CREGU-UMR, Vandoeuvre-les-Nancy (France); Walgenwitz, F. [CSTJF, TotalFinaElf, Pau (France)

2002-06-01

Fluid inclusions study and multi-techniques quantitative analyses have been coupled to reconstitute PVTX conditions of aqueous and petroleum fluid entrapment of a local Haltenbanken area (well 6507/2-2) from the Garn Formation. Unusual low temperature behaviour showing the liquid portion separating into two liquids has been described. This behaviour is typical of a gas condensate/volatile mixture with high methane content and heavy alkanes. The variable liquid-vapour ratio, compositions and morphologies of all petroleum inclusions can be interpreted as a result of a combination of heterogeneous trapping and necking down. Thus, all petroleum inclusions can be related to a single petroleum source. Three main episodes of fluid entrapment can be distinguished. The first one corresponds to the water trapped within detrital quartz microfractures, at around 50{sup o}C and 50 bar; the second to the petroleum fluid arrival in the biphase field of a critical system around 100-120{sup o}C and 190-230 bar. The third one to the main trapping of present-day petroleum inclusions during the recrystallisation of quartz cements (around 110-160{sup o}C and 230-280 bar) within the last few million years of a short and relatively rapid burial.(author)

Formation and Evolution of the Continental Lithospheric Mantle: Perspectives From Radiogenic Isotopes of Silicate and Sulfide Inclusions in Macrodiamonds

Science.gov (United States)

Shirey, S. B.; Richardson, S. H.

2007-12-01

Silicate and sulfide inclusions that occur in diamonds comprise the oldest (>3 Ga), deepest (>140 km) samples of mantle-derived minerals available for study. Their relevance to the evolution of the continental lithosphere is clear because terrestrial macrodiamonds are confined to regions of the Earth with continental lithospheric mantle keels. The goals of analytical work on inclusions in diamond are to obtain paragenesis constraints, radiogenic ages, and initial isotopic compositions. The purpose is to place diamond formation episodes into the broader framework of the geological processes that create and modify the continental lithosphere and to relate the source of the C and N in diamond-forming fluids to understanding the Earth's C and N cycles in the Archean. Although sulfide and silicate inclusions rarely occur in the same diamond, they both can be grouped according to their geochemical similarity with the chief rock types that comprise the mantle keel: peridotite and eclogite. Silicate inclusions are classified as harzburgitic (depleted; olivine > Fo91, garnet Cr2O3 > 3 wt% and CaO from 0 to 5 wt%), lherzolitic (fertile), or eclogitic (basaltic; garnet Cr2O3 14 wt%; Os > 2 ppm) versus eclogitic (Ni bearing kimberlites, and the generosity of mining companies because of the extreme rarity of inclusions in suites of mostly gem-quality diamonds. Most isotopic work has been on the Kaapvaal-Zimbabwe craton with lesser work on the Slave, Siberian, and Australian cratons. Sm-Nd ages on silicate suites and Re-Os ages on sulfide suites confirm diamond formation from the Mesoarchean though the Neoproterozoic. Most important are the systematics across cratons in the context of crustal geology that lead to generalities about craton evolution. Inclusion suites date mantle keels as Mesoarchean and clearly point to subduction as the major process to form the earliest continental nuclei and to amalgamate the cratons in their present form. This is evident from the elevated

Inclusion bodies of aggregated hemosiderins in liver macrophages.

Science.gov (United States)

Hayashi, Hisao; Tatsumi, Yasuaki; Wakusawa, Shinya; Shigemasa, Ryota; Koide, Ryoji; Tsuchida, Ken-Ichi; Morotomi, Natsuko; Yamashita, Tetsuji; Kumagai, Kotaro; Ono, Yukiya; Hayashi, Kazuhiko; Ishigami, Masatoshi; Goto, Hidemi; Kato, Ayako; Kato, Koichi

2017-12-01

Hemosiderin formation is a structural indication of iron overload. We investigated further adaptations of the liver to excess iron. Five patients with livers showing iron-rich inclusions larger than 2 µm were selected from our database. The clinical features of patients and structures of the inclusions were compared with those of 2 controls with mild iron overload. All patients had severe iron overload with more than 5000 ng/mL of serum ferritin. Etiologies were variable, from hemochromatosis to iatrogenic iron overload. Their histological stages were either portal fibrosis or cirrhosis. Inclusion bodies were ultra-structurally visualized as aggregated hemosiderins in the periportal macrophages. X-ray analysis always identified, in addition to a large amount of iron complexes including oxygen and phosphorus, a small amount of copper and sulfur in the mosaic matrixes of inclusions. There were no inclusions in the control livers. Inclusion bodies, when the liver is loaded with excess iron, may appear in the macrophages as isolated organella of aggregated hemosiderins. Trace amounts of copper-sulfur complexes were always identified in the mosaic matrices of the inclusions, suggesting cuproprotein induction against excess iron. In conclusion, inclusion formation in macrophages may be an adaptation of the liver loaded with excess iron.

Final Report - Phase II - Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study

Energy Technology Data Exchange (ETDEWEB)

Peyton, Brent; Sani, Rajesh

2006-09-28

Our understanding of subsurface microbiology is hindered by the inaccessibility of this environment, particularly when the hydrogeologic medium is contaminated with toxic substances. Past research in our labs indicated that the composition of the growth medium (e.g., bicarbonate complexation of U(VI)) and the underlying mineral phase (e.g., hematite) significantly affects the rate and extent of U(VI) reduction and immobilization through a variety of effects. Our research was aimed at elucidating those effects to a much greater extent, while exploring the potential for U(IV) reoxidation and subsequent re-mobilization, which also appears to depend on the mineral phases present in the system. The project reported on here was an extension ($20,575) of the prior (much larger) project. This report is focused only on the work completed during the extension period. Further information on the larger impacts of our research, including 28 publications, can be found in the final report for the following projects: 1) Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study Grant # DE-FG03-01ER63270, and 2) Acceptable Endpoints for Metals and Radionuclides: Quantifying the Stability of Uranium and Lead Immobilized Under Sulfate Reducing Conditions Grant # DE-FG03-98ER62630/A001 In this Phase II project, the toxic effects of uranium(VI) were studied using Desulfovibrio desulfuricans G20 in a medium containing bicarbonate or 1, 4-piperazinediethane sulfonic acid disodium salt monohydrate (PIPES) buffer (each at 30 mM, pH 7). The toxicity of uranium(VI) was dependent on the medium buffer and was observed in terms of longer lag times and in some cases, no measurable growth. The minimum inhibiting concentration (MIC) was 140 M U(VI) in PIPES buffered medium. This is 36 times lower than previously reported for D. desulfuricans. These results suggest that U(VI) toxicity and the detoxification mechanisms of G20 depend greatly on the

Quality Enhancement by Inclusion Complex Formation of Simvastatin Tablets

Directory of Open Access Journals (Sweden)

Emőke Rédai

2013-08-01

Full Text Available Introduction: Simvastatin is an inhibitor of hydroxy-methyl-glutaryl-coenzyme A reductase, used in the treatment of hypercholesterolemia. To enhance its bioavailability by inclusion complexation, as host molecule randommethyl-β-cyclodextrin had been used. After evaluating the complexes we chose the kneading product in 1:2 molar ratio for incorporation of 10 mg simvastatin tablets. Materials and methods: We prepared homogenous mixtures of the inclusion complex and some excipients. The tablets were prepared by direct compression. The tablets were evaluated in regard to: weight uniformity, thickness, diameter, hardness, friability, disintegration and dissolution profile. Results: Weights are in the range of 196-208 mg, diameter 6.83-6.86 mm, height 3.86-4.01 mm, hardness 78.3-113.1 N, friability 0.75- 1.19 %, disintegration above 15 minutes. The dissolved amounts of simvastatin from the tablets are higher compared to the dissolution of pure simvastatin, but lower than the dissolution of the complex itself. Excipients, like disintegrants and lubricants greatly influence the dissolution properties of the tablets. Conclusions: According to our results, tablets containing inclusion complex of simvastatin exhibit better solubility, according to the dissolved amount of simvastatin, than pure drug alone. Proper physical parameters of the tablets are obtained by application of 5 % Primellose

Melt inclusions: Chapter 6

Science.gov (United States)

,; Lowenstern, J. B.

2014-01-01

Melt inclusions are small droplets of silicate melt that are trapped in minerals during their growth in a magma. Once formed, they commonly retain much of their initial composition (with some exceptions) unless they are re-opened at some later stage. Melt inclusions thus offer several key advantages over whole rock samples: (i) they record pristine concentrations of volatiles and metals that are usually lost during magma solidification and degassing, (ii) they are snapshots in time whereas whole rocks are the time-integrated end products, thus allowing a more detailed, time-resolved view into magmatic processes (iii) they are largely unaffected by subsolidus alteration. Due to these characteristics, melt inclusions are an ideal tool to study the evolution of mineralized magma systems. This chapter first discusses general aspects of melt inclusions formation and methods for their investigation, before reviewing studies performed on mineralized magma systems.

Inclusive discourses in early childhood education?

DEFF Research Database (Denmark)

Warming, Hanne

2011-01-01

This article explores the discursive formation of inclusion in early childhood education and after-school (recreation) centres in a Danish municipality. While inclusion has been a central educational issue in research and practice for well over quarter of a century, with continuing emphasis...... worldwide on 'initiatives by governments', this interest has centred on the school environment and institutions of higher education. Thus, despite increasing recognition of the significance of preschool and after-school-care, inclusion in these environments remains peripheral to the main debate....

Thermodynamic investigation on the formation of inclusions containing MgAl2O4 spinel during 16Cr-14Ni austenitic stainless steel manufacturing processes

International Nuclear Information System (INIS)

Park, J.H.

2008-01-01

The formation mechanism of the inclusions containing the spinel crystals has been developed based on the experimental results for the equilibrium between the Fe-16%Cr-14%Ni stainless steel melts and the inclusions as well as the compositions of the inclusions in the plant samples. In the laboratory experiments, the molar content of alumina in the inclusions linearly increases with increasing content of aluminum according to the theoretical expectation and the composition of the inclusions could be described as a function of the activity of aluminum and silicon. From the analysis of the plant samples, the content of MgO and Al 2 O 3 in the calcium silicate type inclusions continuously increases as the steel melts transfer from AOD converter to LT processes and thus, the spinel phase could be crystallized and grown in the calcium silicate matrix during cooling through tundish to cast slabs. On the other hand, the manganese silicate type inclusions were observed after tapping molten steel to the ladle, and then the MnO and Cr 2 O 3 (and SiO 2 ) in the inclusions were reduced by silicon and aluminum through LT to CC mold. The fraction of the inclusions containing spinel crystals at cast slabs was null at (Al 2 O 3 ) 2 O 3 ) > 20 mass%

Small lead and indium inclusions in aluminium

International Nuclear Information System (INIS)

Johnson, E.; Hjemsted, K.; Schmidt, B.; Bourdelle, K.K.; Johansen, A.; Andersen, H.H.; Sarholt-Kristensen, L.

1992-01-01

This paper reports implantation of lead or indium into aluminum results in spontaneous phase separation and formation of lead or indium precipitates. The precipitates grow in topotactical alignment with the matrix, giving TEM images characterized by moire fringes. The size and density of the precipitates increase with increasing fluence until coalescence begins to occur. Implantation at elevated temperatures lead to formation of large precipitates with well developed facets. This is particularly significant for implantation above the bulk melting point of the implanted species. Melting and solidification have been followed by in-situ TEM heating and cooling experiments. Superheating up to ∼50 K above the bulk melting point has been observed, and the largest inclusions melt first. Melting is associated with only partial loss of facetting of the largest inclusion. Initial growth of the inclusions occurs by trapping of atoms retained in supersaturated solution. Further growth occurs by coalescence of neighboring inclusion in the liquid phase. Solidification is accompanied by a strong undercooling ∼30 K below the bulk melting point, where the smallest inclusions solidify first. Solidification is characterized by spontaneous restoration of the facets and the topotactical alignment

Immobilization and Limited Reoxidation of Technetium-99 by Fe(II)-Goethite

International Nuclear Information System (INIS)

Um, Wooyong; Chang, Hyun-shik; Icenhower, Jonathan P.; Qafoku, Nikolla; Smith, Steven C.; Serne, R. Jeffrey; Buck, Edgar C.; Kukkadapu, Ravi K.; Bowden, Mark E.; Westsik, Joseph H.; Lukens, Wayne W.

2010-01-01

-ray diffraction analysis. The presence of goethite in final Tc-goethite Sample 2-5 was also confirmed with the widespread observation of its characteristic acicular (needle-shaped) habit in transmission electron microscopy/scanning electron microscopy images. No Fe-carbonate minerals were found in any Tc-goethite samples, even in the experiments conducted with Tc-laden off-gas scrubber waste simulant containing high concentrations of ammonium carbonate. Analysis of the solid precipitate using x-ray absorption fine structure spectroscopy showed that the dominant oxidation state of Tc in the final Tc-goethite solid product was Tc(IV). Further, the Tc(IV) was in octahedral coordination with Tc-O, Fe-O, and Tc-Fe inter-atomic distances that are consistent with direct substitution of Tc for Fe in the magnetite or goethite structure. Powdered solids and monolithic cylindrical pellets of Tc-goethite were exposed to dilute leaching solutions (buffered at pH values of 4, 7, and 10), synthetic Hanford vadose zone pore water (pH = 7.2 and I = 0.05 M), and Integrated Disposal Facility glass leachate solution (pH = 9.7 and I = 1.67 M), simulating geochemical conditions in the postulated waste disposal vault for up to 180 days in static batch reactors. Although Tc-sequestered goethite samples were exposed to various fluids and different leaching conditions (air and water), the reduced Tc(IV) was not reoxidized to Tc(VII), even after 180 days of reaction in both solution and air conditions. In the circumneutral Hanford pore water solution, the concentration of leached Tc from the goethite pellet was very low, and an effective diffusion coefficient of 6.15 x 10 -11 cm 2 /s was calculated. Successful incorporation of Tc(IV) within the goethite mineral lattice and subsequent goethite armoring, as prepared for Sample 2-5, limited reoxidation of Tc(IV) and its subsequent release from the Tc-goethite waste form, even when the final product was placed in oxidizing environments that typify shallow

Dangling bonds and crystalline inclusions in amorphous materials

Energy Technology Data Exchange (ETDEWEB)

Ferrari, L [Ferrara Univ. (Italy). Ist. di Matematica; Russo, G [Bologna Univ. (Italy). Ist. di Fisica

1981-02-07

It is suggested that on the surface of crystalline inclusions dangling bond formation is favoured due to unbalanced local stresses. The energy for bond tearings is probably originated from the exothermic process leading to the crystalline inclusion configuration which is more stable than the original amorphous one. A thermodynamical calculation is performed giving the ratio nsub(k) of crystalline inclusions having k dangling bonds on their surface.

Inclusion bodies are a site of ebolavirus replication.

Science.gov (United States)

Hoenen, Thomas; Shabman, Reed S; Groseth, Allison; Herwig, Astrid; Weber, Michaela; Schudt, Gordian; Dolnik, Olga; Basler, Christopher F; Becker, Stephan; Feldmann, Heinz

2012-11-01

Inclusion bodies are a characteristic feature of ebolavirus infections in cells. They contain large numbers of preformed nucleocapsids, but their biological significance has been debated, and they have been suggested to be aggregates of viral proteins without any further biological function. However, recent data for other viruses that produce similar structures have suggested that inclusion bodies might be involved in genome replication and transcription. In order to study filovirus inclusion bodies, we fused mCherry to the ebolavirus polymerase L, which is found in inclusion bodies. The resulting L-mCherry fusion protein was functional in minigenome assays and incorporated into virus-like particles. Importantly, L-mCherry fluorescence in transfected cells was readily detectable and distributed in a punctate pattern characteristic for inclusion bodies. A recombinant ebolavirus encoding L-mCherry instead of L was rescued and showed virtually identical growth kinetics and endpoint titers to those for wild-type virus. Using this virus, we showed that the onset of inclusion body formation corresponds to the onset of viral genome replication, but that viral transcription occurs prior to inclusion body formation. Live-cell imaging further showed that inclusion bodies are highly dynamic structures and that they can undergo dramatic reorganization during cell division. Finally, by labeling nascent RNAs using click technology we showed that inclusion bodies are indeed the site of viral RNA synthesis. Based on these data we conclude that, rather than being inert aggregates of nucleocapsids, ebolavirus inclusion bodies are in fact complex and dynamic structures and an important site at which viral RNA replication takes place.

Inclusive education teacher: reflections from a comprehensive curruculum approach

Directory of Open Access Journals (Sweden)

Soraia Napoleão Freitas

2012-08-01

Full Text Available The Brazilian educational policy of inclusion can still be considered recent. The educational agents acting, that can accomplishthis inclusive proposal of students with special needs, can be seen in this process, from the current legislation. The objective of this focal bibliographical study is to describe the socio-cultural and educational changes considering science advances looking for an interpretation for transformations and the changing need in the teacher’s formation emphasizing the development of actions in the perspective of inclusive education. It was found that four factors, related to the teacher’s formation and acting, are crucial to an analysis that allows the performance of the teacher in view of effective inclusion. They are: socio-cultural and educational transformations, curriculum,subjective aspects of the individual teacher and the teaching process. It is concluded that the performance of the teacher in contemporary, beyond their initial training requires understanding, for an innovative performance that reaches the goals of inclusive education.

The role of the University in the context of Inclusive Education Policy: reflections about human resources formation and knowledge production

Directory of Open Access Journals (Sweden)

Rosana Glat

2010-12-01

Full Text Available The present text aims to discuss and present, briefly action lines about the role of University in the promotion of psicossocial and educational development of people with handicap and other special needs. Taking the framework of specialized literature, it brings different questions dealing with human resources formation, specially, teacher formation, and the production of knowledge in the area of Special Education, obtained through research and extension projects, done, preferentially, in partnership with the educational agents that work in the field. It also analyses how these actions may influence the implementation of policies regarding school, labor, and social inclusion of people with handicap and other developmental disorders.

Lead inclusions in aluminium

International Nuclear Information System (INIS)

Johnson, E.; Johansen, A.; Sarholt-Kristensen, L.; Andersen, H.H.; Grabaek, L.; Bohr, J.

1990-01-01

Ion implantation at room temperature of lead into aluminum leads to spontaneous phase separation and formation of lead precipitates growing topotactically with the matrix. Unlike the highly pressurized (∼ 1-5 GPa) solid inclusions formed after noble gas implantations, the pressure in the lead precipitates is found to be less than 0.12 GPa. Recently the authors have observed the result that the lead inclusions in aluminum exhibit both superheating and supercooling. In this paper they review and elaborate on these results. Small implantation-induced lead precipitates embedded in an aluminum matrix were studied by x-ray diffraction

Fluid inclusion studies of calcite veins from Yucca Mountain, Nevada, Tuffs: Environment of formation

Energy Technology Data Exchange (ETDEWEB)

Roedder, E. [Harvard Univ., Cambridge, MA (United States); Whelan, J.F. [Geological Survey, Denver, CO (United States); Vaniman, D.T. [Los Alamos National Lab., NM (United States)

1994-12-31

Calcite vein and vug fillings at four depths (130-314m), all above the present water table in USW G-1 bore hole at Yucca Mountain, Nevada, contain primary fluid inclusions with variable vapor/liquid raitos: Most of these inclusions are either full of liquid or full of vapor. The liquid-filled inclusions show that most of the host calcite crystallized from fluids at <100{degrees}C. The vapor-filled inclusions provide evidence that a separate vapor phase was present in the fluid during crystallization. Studies of these vapor-filled inclusions on the microscope crushing stage were interpreted in an earlier paper as indicating trapping of an air-water-CO{sub 2} vapor phase at ``<100{degrees}C``. Our new studies reveal the additional presence of major methane in the vapor-filled inclusion, indicating even lower temperatures of trapping, perhaps at near-surface temperatures. They also show that the host calcite crystals grew from a flowing film of water on the walls of fractures open to the atmosphere, the vapor-filled inclusions representing bubbles that exsolved from this film onto the crystal surface.

Thermodynamics of inclusion complex formation of β-cyclodextrin with a variety of surfactants differing in the nature of headgroup

International Nuclear Information System (INIS)

Benkő, Mária; Király, Zoltán

2012-01-01

Highlights: ► Inclusion complexation of β-cyclodextrins with various surfactants. ► Thermodynamic parameters determined by titration microcalorimetry. ► Stoichiometry of complexation is 1:1. ► The binding constant decreases linearly with increasing temperature. ► Enthalpy–entropy compensation is independent of the nature of the headgroup. - Abstract: The inclusion complexation of β-cyclodextrin with various surfactants, possessing the same alkyl chain length but differing in the hydrophilic headgroup, was investigated by isothermal titration microcalorimetry. Sodium dodecyl sulfate, sodium dodecyl sulfonate, dodecyltrimethylammonium bromide and dodecyl(dimethyl)amine oxide were investigated. The major aim of this study was to elucidate the effects of temperature and the nature of the headgroup on the complex formation. Thermometric titrations were effected between the temperatures (288 and 348) K. The results provided the stoichiometry, the equilibrium constant and the reaction enthalpy of complexation. Changes in Gibbs energy, entropy and van’t Hoff enthalpy were additionally calculated.

Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies

NARCIS (Netherlands)

Schipper-Krom, Sabine; Juenemann, Katrin; Jansen, Anne H.; Wiemhoefer, Anne; van den Nieuwendijk, Rianne; Smith, Donna L.; Hink, Mark A.; Bates, Gillian P.; Overkleeft, Hermen; Ovaa, Huib; Reits, Eric

2014-01-01

Neurodegenerative disorders such as Huntington's disease are hallmarked by neuronal intracellular inclusion body formation. Whether proteasomes are irreversibly recruited into inclusion bodies in these protein misfolding disorders is a controversial subject. In addition, it has been proposed that

Microbially-Enhanced Redox Solution Reoxidation for Sour Natural Gas Sweetening

Energy Technology Data Exchange (ETDEWEB)

Kenneth Brezinsky

2008-01-15

The specific objective of this project are to advance the technology and improve the economics of the commercial iron-based chelate processes such as LO-CAT II and SulFerox process utilizing biologically enhanced reoxidation of the redox solutions used in these processes. The project is based on the use of chelated ferric iron as the catalyst for the production of elemental sulfur, and then oxidizing bacteria, such as Thiobacillus Ferrooxidans (ATCC 23270) as an oxidizer. The regeneration of Fe{sup 3+} - chelate is accomplished by the use of these same microbes under mild conditions at 25-30 C and at atmospheric pressure to minimize the chelate degradation process. The pH of the redox solution was observed to be a key process parameter. Other parameters such as temperature, total iron concentration, gas to liquid ratio and bacterial cell densities also influence the overall process. The second part of this project includes experimental data and a kinetic model of microbial H{sub 2}S removal from sour natural gas using thiobacillus species. In the experimental part, a series of experiments were conducted with a commercial chelated iron catalyst at pH ranges from 8.7 to 9.2 using a total iron concentration range from 925 ppm to 1050 ppm in the solution. Regeneration of the solution was carried out by passing air through the solution. Iron oxidizing bacteria were used at cell densities of 2.3 x 10{sup 7}cells/ml for optimum effective performance. In the modeling part, oxidation of Fe{sup 2+} ions by the iron oxidizing bacteria - Thiobacillus Ferrooxidans was studied for application to a continuous stirred tank reactor (CSTR). The factors that can directly affect the oxidation rate such as dilution rate, temperature, and pH were analyzed. The growth of the microorganism was assumed to follow Monod type of growth kinetics. Dilution rate had influence on the rate of oxidation of ferrous iron. Higher dilution rates caused washout of the biomass. The oxidation rate was

Study on inclusion interaction of piroxicam with β-cyclodextrin derivatives

Science.gov (United States)

Xiliang, Guo; Yu, Yang; Guoyan, Zhao; Guomei, Zhang; Jianbin, Chao; Shaomin, Shuang

2003-12-01

The inclusion behavior of piroxicam (PX) with β-cyclodextrin (β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD), and carboxymethyl-β-cyclodextrin (CM-β-CD) was investigated by using steady-state fluorescence and nuclear magnetic resonance (NMR) technique. The various factors affecting the inclusion process were examined in detail. The remarkable fluorescence emission enhancement upon addition of CDs suggested that cyclodextrins (CDs) were most suitable for inclusion of the uncharged species of PX. The stoichiometry of the PX-CDs inclusion complexes was 1:1, except for β-CD where a 1:2 inclusion complex was formed. The formation constants showed the strongest inclusion capacity of β-CD. NMR showed the inclusion mode of PX with CDs.

Fluid inclusion studies of calcite veins from Yucca Mountain, Nevada, Tuffs: Environment of formation

International Nuclear Information System (INIS)

Roedder, E.; Whelan, J.F.; Vaniman, D.T.

1994-01-01

Calcite vein and vug fillings at fourth depths (130-314m), all above the present water table in USW G-1 bore hole at Yucca Mountain, Nevada, contain primary fluid inclusions with variable vapor/liquid ratios: most of these inclusions are either full of liquid or full of vapor. The liquid-filled inclusions show that most of the host calcite crystallized from fluids at 2 vapor phase at open-quotes 100 degrees Cclose quotes. Our new studies reveal the additional presence of major methane in the vapor-filled inclusion, indicating even lower temperatures of trapping, perhaps at near-surface temperatures. They also show that the host calcite crystals grew from a flowing film of water on the walls of fractures open to the atmosphere, the vapor-filled inclusions representing bubbles that exsolved from this film onto the crystal surface

Fluid inclusion studies of calcite veins from Yucca Mountain, Nevada, Tuffs: Environment of formation

International Nuclear Information System (INIS)

Roedder, E.; Whelan, J.F.; Vaniman, D.T.

1994-01-01

Calcite vein and vug fillings at four depths (130-314m), all above the present water table in USW G-1 bore hole at Yucca Mountain, Nevada, contain primary fluid inclusions with variable vapor/liquid raitos: Most of these inclusions are either full of liquid or full of vapor. The liquid-filled inclusions show that most of the host calcite crystallized from fluids at 2 vapor phase at ''<100 degrees C''. Our new studies reveal the additional presence of major methane in the vapor-filled inclusion, indicating even lower temperatures of trapping, perhaps at near-surface temperatures. They also show that the host calcite crystals grew from a flowing film of water on the walls of fractures open to the atmosphere, the vapor-filled inclusions representing bubbles that exsolved from this film onto the crystal surface

Final Report - Phase II - Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study ($20,575 extension)

International Nuclear Information System (INIS)

Brent Peyton; Rajesh Sani

2006-01-01

Our understanding of subsurface microbiology is hindered by the inaccessibility of this environment, particularly when the hydrogeologic medium is contaminated with toxic substances. Past research in our labs indicated that the composition of the growth medium (e.g., bicarbonate complexation of U(VI)) and the underlying mineral phase (e.g., hematite) significantly affects the rate and extent of U(VI) reduction and immobilization through a variety of effects. Our research was aimed at elucidating those effects to a much greater extent, while exploring the potential for U(IV) reoxidation and subsequent re-mobilization, which also appears to depend on the mineral phases present in the system. The project reported on here was an extension ($20,575) of the prior (much larger) project. This report is focused only on the work completed during the extension period. Further information on the larger impacts of our research, including 28 publications, can be found in the final report for the following projects: (1) Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study Grant DE-FG03-01ER63270, and (2) Acceptable Endpoints for Metals and Radionuclides: Quantifying the Stability of Uranium and Lead Immobilized Under Sulfate Reducing Conditions Grant DE-FG03-98ER62630/A001 In this Phase II project, the toxic effects of uranium(VI) were studied using Desulfovibrio desulfuricans G20 in a medium containing bicarbonate or 1, 4-piperazinediethane sulfonic acid disodium salt monohydrate (PIPES) buffer (each at 30 mM, pH 7). The toxicity of uranium(VI) was dependent on the medium buffer and was observed in terms of longer lag times and in some cases, no measurable growth. The minimum inhibiting concentration (MIC) was 140 (micro)M U(VI) in PIPES buffered medium. This is 36 times lower than previously reported for D. desulfuricans. These results suggest that U(VI) toxicity and the detoxification mechanisms of G20 depend greatly

Using Ce to modify inclusion in spring steel

Directory of Open Access Journals (Sweden)

Wang Q.

2017-01-01

Full Text Available The effect of rare earth metals addition on the Al2O3 inclusions in spring steel used in fastener of high speed railway was investigated by metallographic examination, SEM-EDS and composition analysis. To deform those harmful inclusions to improve material performance，the evolution process of Al2O3 inclusions was investigated through the surface and line scanning. Ce metal modifying Al2O3 is a stepwise reduction process based on a formation of ring shape Ce-riched band around the Al2O3 inclusions during reaction process. Through experiment and thermodynamic calculation, an evolvement rule about Al2O3 inclusions change after Ce addition is obtained, i.e. Al2O3→Ce2O3-Al2O3→Ce2O2S. Changing the inclusions from Al2O3 to rare earth inclusions could improve the resistance to pitting corrosion based on potentiodynamic anodic polarization test.

Inclusive practices in teacher training in Mexico

Directory of Open Access Journals (Sweden)

Vasthi Jocabed Flores Barrera

2017-06-01

Full Text Available Inclusive practices include diversity as a resource that favors teaching-learning processes in the classroom, although they focus on the most vulnerable people by offering them higher-quality education. This descriptive study sought to identify the inclusive practices of teachers who train teachers in an Escuela Normal (teachers’ college in Mexico. Eight teachers and 247 students participated in the study; the Guidelines for the Evaluation of Inclusive Practices in the Classroom (observation formats and students, the Learning Strategies Questionnaire, and semi-structured interviews were used. The results suggest that, although the general perception is that participating teachers have high inclusive practices, they need greater support in the physical conditions of the classroom, methodology and teacher-student relationship. It was also identified the need for a refresher program for teachers to conceptually enrich the teaching staff and encourage the implementation of inclusive education within the Escuela Normal.

Anomalous Fe and Mn heterogeneity observed in microscopic inclusions in diamond using nuclear microscopy

International Nuclear Information System (INIS)

Sideras-Haddad, E.; Hart, R.J.; Connell, S.H.; Sellschop, J.P.F.; Tredoux, M.

1999-01-01

A Fe and Mn heterogeneity effect was observed in microscopic garnet inclusion in diamond using micro-PIXE. Results are presented and the implications of these disequilibrium element distributions during growth of garnets are discussed. The occurrence of zoning or any type of chemical inhomogeneity within inclusions encapsulated within diamond has implications on the age of formation of the inclusion and the diamond. It is believed that the age of the inclusion is that of the diamond formation itself, with subsequent isolation of the inclusion from the mantle by the diamond. The significance of the chemical heterogeneity or zoning is that it should not exist given the high temperature and long time of encapsulation

Nanosized f.c.c. thallium inclusions in aluminium

International Nuclear Information System (INIS)

Johnson, E.; Johansen, A.; Thoft, N.B.; Andersen, H.H.; Sarholt-Kristensen, L.

1993-01-01

Ion implantation of pure aluminium with thallium induces the formation of nanosized crystalline inclusions of thallium with a f.c.c. structure. The size of the inclusions depends on the implantation conditions and subsequent annealing treatments and is typically in the range from 1 to 10 nm. The inclusions are aligned topotactically with the aluminium matrix with a cube-cube orientation relationship and they have a truncated octahedral shape bounded by {111} and {001} planes. The lattice parameter of the f.c.c. thallium inclusions is 0.484 ± 0.002 nm, which is slightly but significantly larger than in the high-pressure f.c.c. thallium phase known to be stable above 3.8 GPa. (Author)

Towards an Inclusive Pedagogical Culture: Experiences from University Practice

Directory of Open Access Journals (Sweden)

Iliana María Fernández-Fernández

2016-09-01

Full Text Available In this paper, we deal with conceptual and methodological elements to develop the pedagogical inclusive competence of the professors of higher education in Ecuador. We analyze the current conceptions and the main drawbacks related to the inclusion process in the university environment nowadays. We support a theoretical procedural model, and from the practical standpoint, we implemented the methodological procedures structured in a map of processes to reach an inclusive formative process. The main results are given in the development of the pedagogical inclusive competence and the increase of the inclusion culture at the university, and revealed in the improvement of university curriculum from an inclusive approach, the betterment of the physical and technological infrastructure, the permanent upgrading of professors and putting into practice policies of affirmative action.

Study of inclusion complex formation between chlorpromazine hydrochloride, as an antiemetic drug, and β-cyclodextrin, using conductometric technique

International Nuclear Information System (INIS)

Rafati, Amir Abbas; Hamnabard, Nazanin; Ghasemian, Ensieh; Nojini, Zabiolah Bolboli

2009-01-01

The behavior of micellization of chlorpromazine hydrochloride (CPH) as an antiemetic drug and its inclusion complex formation with β-cyclodextrin (β-CD) was studied using conductometric technique. The binding or association constant of the complexation equilibrium is evaluated from conductometric measurements by using a nonlinear regression method. The resulting K values for micellization as well as complexation are analyzed. The experiments were carried out at different temperatures. It has been found that CPH form only the 1:1 complex. The association constant values are used for evaluation of thermodynamic parameters of complexation, such as ΔG complex o , ΔH complex o and ΔS complex o .

Eclogitic inclusions in diamonds: Evidence of complex mantle processes over time

Science.gov (United States)

Taylor, Lawrence A.; Snyder, Gregory A.; Crozaz, Ghislaine; Sobolev, Vladimir N.; Yefimova, Emiliya S.; Sobolev, Nikolai V.

1996-08-01

The first ion-probe trace element analyses of clinopyroxene-garnet pairs both included within diamonds and from the eclogite host xenoliths are reported; these diamondiferous eclogites are from the Udachnaya and Mir kimberlite pipes, Yakutia, Russia. The major and trace element analyses of these diamond-inclusion and host-rock pairs are compared in order to determine the relative ages of the diamonds, confirm or deny genetic relationships between the diamonds and the eclogites, evaluate models of eclogite petrogenesis, and model igneous processes in the mantle before, during, and after diamond formation. The most striking aspect of the chemical compositions of the diamond inclusions is the diversity of relationships with their eclogite hosts. No single distinct pattern of variation from diamond inclusion minerals to host minerals is found for all four samples. Garnet and clinopyroxene inclusions in the diamonds from two samples (U-65/3 and U-66/3) have lower Mg#s, lower Mg, and higher Fe contents, and lower LREE than those in the host eclogite. We interpret such variations as due to metasomatism of the host eclogite after diamond formation. One sample, U-41/3 shows enrichment in diamond-inclusion MREE enrichment relative to the eclogite host and may indicate a metasomatic event prior to, or during, diamond formation. Bulanova [2] found striking differences between inclusions taken from within different portions of the very same diamond. Clinopyroxene inclusions taken from the central (early) portions of Yakutian diamonds were lower in Mg# and Mg contents (by up to 25%) than those later inclusions at the rims of diamonds. These trends are parallel to those between diamond inclusions and host eclogites determined for four of the five samples from the present study and may merely represent changing magmatic and/or P-T conditions in the mantle. Garnet trace element compositions are similar in relative proportions, but variable in abundances, between diamond inclusions

Structure and organization of nanosized-inclusion-containing bilayer membranes

Science.gov (United States)

Ren, Chun-Lai; Ma, Yu-Qiang

2009-07-01

Based on a considerable amount of experimental evidence for lateral organization of lipid membranes which share astonishingly similar features in the presence of different inclusions, we use a hybrid self-consistent field theory (SCFT)/density-functional theory (DFT) approach to deal with bilayer membranes embedded by nanosized inclusions and explain experimental findings. Here, the hydrophobic inclusions are simple models of hydrophobic drugs or other nanoparticles for biomedical applications. It is found that lipid/inclusion-rich domains are formed at moderate inclusion concentrations and disappear with the increase in the concentration of inclusions. At high inclusion content, chaining of inclusions occurs due to the effective depletion attraction between inclusions mediated by lipids. Meanwhile, the increase in the concentration of inclusions can also cause thickening of the membrane and the distribution of inclusions undergoes a layering transition from one-layer structure located in the bilayer midplane to two-layer structure arranged into the two leaflets of a bilayer. Our theoretical predictions address the complex interactions between membranes and inclusions suggesting a unifying mechanism which reflects the competition between the conformational entropy of lipids favoring the formation of lipid- and inclusion-rich domains in lipids and the steric repulsion of inclusions leading to the uniform dispersion.

Towards revealing the structure of bacterial inclusion bodies.

Science.gov (United States)

Wang, Lei

2009-01-01

Protein aggregation is a widely observed phenomenon in human diseases, biopharmaceutical production, and biological research. Protein aggregates are generally classified as highly ordered, such as amyloid fibrils, or amorphous, such as bacterial inclusion bodies. Amyloid fibrils are elongated filaments with diameters of 6-12 nm, they are comprised of residue-specific cross-beta structure, and display characteristic properties, such as binding with amyloid-specific dyes. Amyloid fibrils are associated with dozens of human pathological conditions, including Alzheimer disease and prion diseases. Distinguished from amyloid fibrils, bacterial inclusion bodies display apparent amorphous morphology. Inclusion bodies are formed during high-level recombinant protein production, and formation of inclusion bodies is a major concern in biotechnology. Despite of the distinctive morphological difference, bacterial inclusion bodies have been found to have some amyloid-like properties, suggesting that they might contain structures similar to amyloid-like fibrils. Recent structural data further support this hypothesis, and this review summarizes the latest progress towards revealing the structural details of bacterial inclusion bodies.

Nuclear forensics. Searching for nuclear device debris in trinitite-hosted inclusions

International Nuclear Information System (INIS)

Bellucci, J.J.; Antonio Simonetti

2012-01-01

This study documents the 3D morphology of trinitite-hosted metallic inclusions and the first observations of alloys consisting primarily of Pb, Ta, Ga, and W. Scanning electron and backscatter electron imaging, as well as energy dispersive X-ray spectra chemical composition data are reported for heavy metal inclusions in 14 different samples of trinitite. Inclusions consisting of Fe-Ti-Si are the most abundant and presumably derived predominantly from the explosion tower. Grains of Cu, Pb, Ta + Ga + W were also observed and are likely derivatives of the trinitite device wiring, tamper, and tamper and core, respectively. Additionally, a Ba-rich grain and multiple zircons (ZrSiO 4 ) were observed in a large majority of samples. The spherical morphology and the ubiquitous positioning of the heavy metal inclusions on the crater walls of the glassy trinitite surfaces indicate a two-step formation. Stage one involves formation of the glassy trinitite, while the second stage involved the precipitation of the inclusions that were incorporated onto the surface of the trinitite. Furthermore, the precarious positioning of these inclusions further emphasizes the need for analysis using non-destructive techniques prior to methods employing a bulk sample digestion approach. (author)

Characterisation of iron inclusion during the formation of calcium sulfoaluminate phase

International Nuclear Information System (INIS)

Idrissi, M.; Diouri, A.; Damidot, D.; Greneche, J.M.; Talbi, M. Alami; Taibi, M.

2010-01-01

The iron distribution among the sulfoaluminate clinker phases and its ability to enter the calcium sulfoaluminate lattice in solid solution can have a significant influence on manufacturing process and reactivity of calcium sulfoaluminate (CSA) cements. X-ray diffraction (XRD) analysis, Moessbauer spectroscopy, scanning electron microscopy (SEM) equipped with an energy dispersive X-ray analysis system (EDAX) and infrared spectroscopy were used to identify the mineralogical conditions of iron inclusion during the formation of calcium sulfoaluminate (C 4 A 3 S) phase from different mixtures in the CaO-Al 2 O 3 -Fe 2 O 3 -SO 3 system. The mixtures, heated in a laboratory electric oven, contained stoichiometric amounts of reagent grade CaCO 3 , Al 2 O 3 , Fe 2 O 3 and CaSO 4 .2H 2 O for the synthesis of Ca 4 Al (6- 2x) Fe 2x SO 16 , where x, comprised between 0 and 3, is the mole number of Al 2 O 3 substituted by Fe 2 O 3 . With x increasing from 0 to 1.5, both the iron content of C 4 A 3 S phase and the amounts of side components such as C 2 F and CS increased. For x values included in the range of 1.5-3.0, at temperatures higher than 1200 o C, melting phenomena were observed and, instead of the C 4 A 3 S solid solution, ferritic phases and anhydrite were formed.

Silicate Inclusions in IAB Irons: Correlations Between Metal Composition and Inclusion Properties, and Inferences for Their Origin

Science.gov (United States)

Benedix, G. K.; McCoy, T. J.; Keil, K.

1995-09-01

do exist. Inclusion mineralogy progresses from graphite-troilite nodules in low Ni IAB's, to silicate-dominated inclusions in high Ni IAB's. With increasing Ni abundance in the metal, systematic variations are found in several properties. Two groups are delineated on a Ni vs Fa content plot and both are positively correlated with Ni content. Graphite abundance noticeably decreases with increasing Ni content [7]. Graphite location also varies with Ni: graphite is primarily found interstitial to the silicates in low Ni IAB's, but is located at metal-silicate boundaries in those with higher Ni abundances. With increasing Ni, daubreelite disappears. Inclusion shape also varies [7]: more angular inclusions are associated with low Ni, while more rounded inclusions exist at high Ni contents. These systematic changes suggest interaction between the silicate inclusions and an evolving metallic magma. Troilite and graphite abundances may be related to early nucleation on silicates, hence their depletion in high Ni (later crystallizing) irons. The presence of abundant graphite creates reducing conditions which would result in the formation of daubreelite. Conditions become more oxidizing with loss of graphite, evidenced by lack of daubreelite and more FeO-rich silicates in high Ni irons. Although an overall trend exists, the story is complicated by heterogeneities. Significant variations are found between paired samples (e.g., Toluca and Tacubaya), as well as within individual inclusions (daubreelite and chromite in same inclusion). Local oxidation conditions may be controlled by graphite abundance. Heterogeneities within specific meteorites need documentation. Most of the inclusions exhibit similar textural (metamorphic) features, but a few show evidence of partial melting and melt migration, further complicating the parent body history. While a variety of processes (oxidation-reduction, metamorphism, partial melting) affected the inclusions during formation, systematic

Occurrence of the malate-aspartate shuttle in various tumor types.

Science.gov (United States)

Greenhouse, W V; Lehninger, A L

1976-04-01

The activity of the malate-aspartate shuttle for the reoxidation of cytoplasmic reduced nicotinamide adenine dinucleotide (NADH) by mitochondria was assessed in six lines of rodent ascites tumor cells (two strains of Ehrlich ascites carcinoma, Krebs II carcinoma, Novikoff hepatoma, AS-30D hepatoma, and L1210 mouse leukemia). All the tumor cells examined showed mitochondrial reoxidation of cytoplasmic NADH, as evidenced by the accumulation of pyruvate when the cells were incubated aerobically with L-lactate. Reoxidation of cytoplasmic NADH thus generated was completely inhibited by the transaminase inhibitor aminooxyacetate. The involvement of the respiratory chain in the reoxidation of cytoplasmic NADH was demonstrated by the action of cyanide, rotenone, and antimycin A, which strongly inhibited the formation of pyruvate from added L-lactate. Compounds that inhibit the carrier-mediated entry of malate into mitochondria, such as butylmalonate, benzenetricarboxylate, and iodobenzylmalonate, also inhibited the accumulation of pyruvate from added L-lactate by the tumor cells. The maximal rate of the malate-aspartate shuttle was established by addtion of arsenite to inhibit the mitochondrial oxidation of the pyruvate formed from added lactate. The capacity of the various tumor lines for the reoxidation of cytoplasmic NADH via the malate-aspartate shuttle approaches 20% of the total respiratory rate of the cells and thus appears to be sufficient to account for the mitochondrial reoxidation of that fraction of glycolytic NADH not reoxidized by pyruvate and lactate dehydrognenase in the cytoplasm.

Designing the robot inclusive space challenge

Directory of Open Access Journals (Sweden)

Rajesh Elara Mohan

2015-11-01

Full Text Available A novel robotic challenge, namely the robot inclusive spaces (RIS challenge, is proposed in this paper, which is a cross disciplinary and design focused initiative. It aims to foster the roboticists, architects, and designers towards realizing robot friendly social spaces. Contrary to conventional robotics competitions focusing on designing robots and its component technologies, robot inclusive spaces challenge adopts an interdisciplinary “design for robots” strategy to overcome the traditional research problem in real world deployments of social robots. In order to realize the RIS, various architectural elements must be adapted including: design principles for inclusive spaces, lighting schemes, furniture choices and arrangement, wall and floor surfaces, pathways among others. This paper introduces the format and design principles of RIS challenge, presents a first run of the challenge, and gives the corresponding analysis.

Cathodoluminescence, fluid inclusions and trace element data for the syntaxial quartz cementation in the sandstones of Ora Formation, northern Iraq

DEFF Research Database (Denmark)

Omer, Muhamed Fakhri; Friis, Henrik

2018-01-01

Quartz cements of the quartz arenitic sandstones from the Chalky Nasara and Ora section of the (Devonian-Carboniferous) Ora Formation in northern Iraq have been studied. A combination of Hot-Cathodoluminescence (CL), LA-ICP-MS and fluid inclusions microthermometry revealed three syntaxial quartz......-bedded sandstones than in the6 thickly-bedded sandstones filling most of remaining pore space during mesogenesis. The Q3 was formed during early telogenesis stage fully cementing the sandstones and the fractures were filled by hydrothermal chlorite and sulfides. Significant amount of trace elements Al, Li, Ge...

Investigation on the inclusion interaction of 4-sulfonatocalix[n]arenes with 1-(4-nitrophenyl)piperazine

Science.gov (United States)

Zhang, Yongbin; Chao, Jianbin; Zhao, Shuhui; Xu, Penghao; Wang, Hongfang; Guo, Zhiqiang; Liu, Diansheng

2014-11-01

The inclusion behaviors of 4-Sulfonatocalix[n]arenes (SCXn) (n = 4, 6, 8) with 1-(4-nitrophenyl)piperazine (NPP) were investigated by UV spectroscopy and fluorescence spectroscopy at different pH values (pH = 3.05, 6.50, 8.40). The UV absorption and fluorescence intensity of NPP remarkably increased in presence of SCXn revealing formation of the inclusion complexes between NPP and SCXn. Moreover, the formation constants (K) of inclusion complexes were also determined by the non-linear fitting method, and the obtained data showed that the formation constants decreased gradually with the increasing of the pH value. When the pH value was 3.05, the formation constant of NPP with SCX8 reached a maximum of 1.7 × 107 L mol-1. The stoichiometric ratio was verified to be 1:1 by the continuous variation method. Meanwhile FT-IR and DSC analysis also indicated that NPP could form the inclusion complex with SCXn. In order to explore the inclusion mechanism of NPP with SCXn, 1H NMR and molecular modeling studies were carried out and experimental results showed that the part of benzene ring of NPP penetrated into the hydrophobic cavity of SCXn.

Amyloid-like protein inclusions in tobacco transgenic plants.

Directory of Open Access Journals (Sweden)

Anna Villar-Piqué

Full Text Available The formation of insoluble protein deposits in human tissues is linked to the onset of more than 40 different disorders, ranging from dementia to diabetes. In these diseases, the proteins usually self-assemble into ordered β-sheet enriched aggregates known as amyloid fibrils. Here we study the structure of the inclusions formed by maize transglutaminase (TGZ in the chloroplasts of tobacco transplastomic plants and demonstrate that they have an amyloid-like nature. Together with the evidence of amyloid structures in bacteria and fungi our data argue that amyloid formation is likely a ubiquitous process occurring across the different kingdoms of life. The discovery of amyloid conformations inside inclusions of genetically modified plants might have implications regarding their use for human applications.

Analysis and simulation of non-metallic inclusions in spheroidal graphite iron

International Nuclear Information System (INIS)

Pustal, B; Schelnberger, B; Bührig-Polaczek, A

2016-01-01

Non-metallic inclusions in spheroidal cast iron (SGI) reduce fatigue strength and yield strength. This type of inclusion usually accumulates at grain boundaries. Papers addressing this topic show the overall impact of both the fraction of so-called white (carbides) and black (non-metallic) inclusions on mechanical properties. In the present work we focus on the origin and the formation conditions of black Mg-bearing inclusions, further distinguishing between Si-bearing and non-Si-bearing Mg inclusions. The formation was simulated applying thermodynamic approaches. Moreover, appropriate experiments have been carried out and a large number of particles have been studied applying innovative feature analysis with regard to shape, size, and composition. Magnesium silicates are predicted at elevated oxygen concentrations, whereas at low levels of oxygen sulphides and carbides appear at a late stage of solidification. Experiments with three consecutive flow obstacles show that the amount of magnesium silicates decrease after each of the three obstacles, whereas the fraction of non-Si-bearing inclusions remains approximately constant. The size of inclusions divides in halves over the flow path and the number of particles increases accordingly. We point out that based on feature analysis Mg-O-C bearing inclusion show disadvantageous form factors for which reason this kind of inclusions may be extremely harmful in terms of crack initiation. All results obtained indicate that magnesium silicates are entrapped on mould filling, whereas Mg-(O, C, S, P, N) bearing particles are precipitates at late stages of solidification. Consequently, the only avoidance strategy is setting up optimum retained magnesium content. (paper)

Formation of inclusion complexes between high amylose starch and octadecyl ferulate via steam jet cooking.

Science.gov (United States)

Kenar, James A; Compton, David L; Little, Jeanette A; Peterson, Steve C

2016-04-20

Amylose-ligand inclusion complexes represent an interesting approach to deliver bioactive molecules. However, ferulic acid has been shown not to form single helical inclusion complexes with amylose from high amylose maize starch. To overcome this problem a lipophilic ferulic acid ester, octadecyl ferulate, was prepared and complexed with amylose via excess steam jet cooking. Jet-cooking octadecyl ferulate and high amylose starch gave an amylose-octadecyl ferulate inclusion complex in 51.0% isolated yield. X-ray diffraction (XRD) and differential scanning calorimetry (DSC) confirmed that a 61 V-type inclusion complex was formed. Amylose and extraction assays showed the complex to be enriched in amylose (91.9±4.3%) and contain 70.6±5.6mgg(-1) octadecyl ferulate, although, minor hydrolysis (∼4%) of the octadecyl ferulate was observed under the excess steam jet-cooking conditions utilized. This study demonstrates that steam jet cooking is a rapid and scalable process in which to prepare amylose-octadecyl ferulate inclusion complexes. Published by Elsevier Ltd.

Evolution of Oxide Inclusions in Si-Mn Killed Steels During Hot-Rolling Process

Science.gov (United States)

Yang, Wen; Guo, Changbo; Zhang, Lifeng; Ling, Haitao; Li, Chao

2017-10-01

The evolution of oxide inclusions in Si-Mn killed steels refined by slags of different basicity during a four-pass industrial hot-rolling process was investigated using an automated microscopy system. High-basicity refining slag induced the formation of CaO- and Al2O3-containing inclusions, while refining slag with 0.8 basicity induced dominant inclusions of SiO2 and MnO-SiO2. CaO-SiO2-Al2O3 inclusions mainly formed endogenously during solidification and cooling of Ca-containing steels, where Ca originated from slag-steel reactions. However, the larger-sized higher-CaO inclusions originated from slag entrainment. Different inclusions presented different hot-rolling behaviors. The inclusion composition changed by deformation and new phase formation. The dominant oxide types were unchanged under refinement by low-basicity slag; however, they changed under refinement with high-basicity slag. The deformation index of inclusions decreased with increasing accumulated reduction (AR) of the steel. The difference in deformation index between different inclusion types was the largest in the first rolling stage and decreased in subsequent stages. SiO2-CaO and SiO2-MnO-CaO inclusions had larger deformation indices during hot rolling but smaller indices in the last two stages. High-basicity slag increased inclusion complexity; from the perspective of cold-drawing performance, low-basicity refining slag is better for the industrial production of tire-cord steels.

Reptured Epidermal Inclusion Cyst in the Axilla: A Case Report

International Nuclear Information System (INIS)

Kim, Kyu Soon; Kim, Hak Hee; Shin, Hee Jeong; Yang, Hye Rin; Sohn, Jeong Hee; Kwon, Gui Young; Gong, Gyung Yub

2006-01-01

Epidermal inclusion cysts, the most common type of simple epithelial cyst, are typically well-encapsulated, subepidermal and mobile nodules. They may occur anywhere, but are mostly found on the scalp, face, neck, trunk, and back. Less than 10% of epidermal inclusion cysts occur on the extremities, and even fewer are found on the palms, soles, and breasts. If epidermal inclusion cysts rupture, foreign body reaction, granulomatous reaction or abscess formation could follow. We described here the sonographic findings of ruptured epidermal inclusion cyst of the right axilla in a 33-year-old woman who presented with a palpable axillary mass forming an inflammatory abscess

Study on inclusion complex of cyclodextrin with methyl xanthine derivatives by fluorimetry

Science.gov (United States)

Wei, Yan-Li; Ding, Li-Hua; Dong, Chuan; Niu, Wei-Ping; Shuang, Shao-Min

2003-10-01

The inclusion complexes of β-cyclodextrin (β-CD) and HP-β-cyclodextrin (HP-β-CD) with caffeine, theophylline and theobromine were investigated by fluorimetry. Various factors affecting the formation of inclusion complexes were discussed in detail including forming time, pH effect and temperature. The results indicate that inclusion process was affected seriously by laying time and pH. The forming time of β-CD inclusion complexes is much longer than that of HP-β-CD. The optimum pH range is about 7-12 for caffeine, 8-10 for TP, 10.5-12 for TB. The intensities of their fluorescence increase with the decreasing of temperature. Their maximum excitation wavelengths are all in the range of 280-290 nm. The emission wavelength of caffeine and theophylline are both in the range of 340-360 nm, and that of theobromine is about 325 nm. The fluorescence signals are intensified with the increasing concentration of CD. The stoichiometry of the inclusion complexes of CD with these three methyl xanthine derivatives are all 1:1 and the formation constant are all calculated.

O papel da gestão na formação inicial de professores com vistas à educação inclusiva - Management’s role on initial formation of teachers aiming to inclusive education

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Charline Fillipin Machado

2015-10-01

Full Text Available Resumo Considerando o atual sistema de educação inclusiva cabe ao ensino regular fornecer a educação básica em todas as esferas. Diante disso, evidencia-se a importância do investimento na formação docente, pois é na academia que se encontra o primeiro e um dos mais importantes ambientes de instrução e troca de saberes, no qual se formam os profissionais que atuarão no amanhã. Esta pesquisa pretendeu verificar quais alternativas organizativas e estruturais a gestão da UFSM está buscando ou deve buscar para colaborar na formação inicial de professores qualificados para atuar na escola inclusiva. Em síntese, a qualidade da formação de professores para trabalhar na educação inclusiva está em construção, problemas ainda são encontrados, principalmente em relação à própria formação dos formadores. Palavras-chave: educação inclusiva, formação inicial de professores, gestão no ensino superior, políticas públicas. MANAGEMENT’S ROLE ON INITIAL FORMATION OF TEACHERS AIMING TO INCLUSIVE EDUCATION Abstract Considering the current inclusive education system, it is up to the regular teaching provide the basic education at all scopes. Facing that, the importance of investing into the teacher’s formation is verified, for it is inside the academy that the first and one of the most important instruction and knowledge exchanging environments is found; there the professionals which will act tomorrow are formed. This research intended to verify which organizational and structural alternatives UFSM’s management is or should be looking for in order to collaborate to a initial formation of teachers with qualification to act inside the inclusive school. In summary, the quality of training of teachers to work inside inclusive education is being built, with troubles being found, especially in relation to the teachers’ formation. Key-words: inclusive education, teacher’s initial formation, superior teaching’s management

Radiation effects on n-hexane-urea inclusion compound

International Nuclear Information System (INIS)

Ohta, Nobuaki; Ozasa, Senichi; Ichikawa, Takahisa

1987-01-01

n-hexane-urea inclusion compounds were γ-irradiated at room temperature and dimers from n-hexane were found to form. Additive effects of 1-hexene, 1-chloropentane, and n-hexylamine to the formation of the dimers have been studied. For the comparison liquid n-hexane systems were also γ-irradiated under the same conditions. The radiation-induced reactions in the inclusion compounds are discussed together with the reactions in the liquid n-hexane systems. The dimers from n-hexane in the inclusion compounds are presumably formed by dimerization of hexyl radicals; the hexyl radicals are possibly produced by hydrogen abstraction of hydrogen atom and/or urea radicals from n-hexane included in urea. (author)

Topological sensitivity based far-field detection of elastic inclusions

Directory of Open Access Journals (Sweden)

Tasawar Abbas

2018-03-01

Full Text Available The aim of this article is to present and rigorously analyze topological sensitivity based algorithms for detection of diametrically small inclusions in an isotropic homogeneous elastic formation using single and multiple measurements of the far-field scattering amplitudes. A L2-cost functional is considered and a location indicator is constructed from its topological derivative. The performance of the indicator is analyzed in terms of the topological sensitivity for location detection and stability with respect to measurement and medium noises. It is established that the location indicator does not guarantee inclusion detection and achieves only a low resolution when there is mode-conversion in an elastic formation. Accordingly, a weighted location indicator is designed to tackle the mode-conversion phenomenon. It is substantiated that the weighted function renders the location of an inclusion stably with resolution as per Rayleigh criterion. 2000 MSC: 35R30, 35L05, 74B05, 47A52, 65J20, Keywords: Inverse elastic scattering, Elasticity imaging, Topological derivative, Resolution analysis, Stability analysis

Social inclusion and inclusive education

Directory of Open Access Journals (Sweden)

Marsela Robo

2014-07-01

In line with global debate on social inclusion and exclusion, the author brings the way this debate has now pervaded both the official and development policy discourse in Albania.Social inclusion is considered as one of the priorities of the current government, with poverty reduction as its main focus, which will be ensured not only through economic development. In the end, the article focuses on the role of education as a very important and useful tool for ensuring social inclusion.Social inclusion through education, in particular through vocational education, considered by the author as the only way towards sustainable development of Albanian society.

Exploration of inclusion complexes of neurotransmitters with β-cyclodextrin by physicochemical techniques

Science.gov (United States)

Roy, Mahendra Nath; Saha, Subhadeep; Kundu, Mitali; Saha, Binoy Chandra; Barman, Siti

2016-07-01

Molecular assemblies of β-cyclodextrin with few of the most important neurotransmitters, viz., dopamine hydrochloride, tyramine hydrochloride and (±)-epinephrine hydrochloride in aqueous medium have been explored by reliable spectroscopic and physicochemical techniques as potential drug delivery systems. Job plots confirm the 1:1 host-guest inclusion complexes, while surface tension and conductivity studies illustrate the inclusion process. The inclusion complexes were characterized by 1H NMR spectroscopy and association constants have been calculated by using Benesi-Hildebrand method. Thermodynamic parameters for the formation of inclusion complexes have been derived by van't Hoff equation, which demonstrate that the overall inclusion processes are thermodynamically favorable.

Elimination of A-type inclusion formation enhances cowpox virus replication in mice: implications for orthopoxvirus evolution.

Science.gov (United States)

Kastenmayer, Robin J; Maruri-Avidal, Liliana; Americo, Jeffrey L; Earl, Patricia L; Weisberg, Andrea S; Moss, Bernard

2014-03-01

Some orthopoxviruses including cowpox virus embed virus particles in dense bodies, comprised of the A-type inclusion (ATI) protein, which may provide long-term environmental protection. This strategy could be beneficial if the host population is sparse or spread is inefficient or indirect. However, the formation of ATI may be neutral or disadvantageous for orthopoxviruses that rely on direct respiratory spread. Disrupted ATI open reading frames in orthopoxviruses such as variola virus, the agent of smallpox, and monkeypox virus suggests that loss of this feature provided positive selection. To test this hypothesis, we constructed cowpox virus mutants with deletion of the ATI gene or another gene required for embedding virions. The ATI deletion mutant caused greater weight loss and higher replication in the respiratory tract than control viruses, supporting our hypothesis. Deletion of the gene for embedding virions had a lesser effect, possibly due to known additional functions of the encoded protein. Published by Elsevier Inc.

Formation of inclusion complexes between high amylose starch and octadecyl ferulate via steam jet cooking

Science.gov (United States)

Amylose can form inclusion complexes with guest molecules and represents an interesting approach to deliver bioactive molecules. However, ferulic acid has been shown not to form single helical inclusion complexes with amylose. To overcome this problem a ferulic acid ester, octadecyl ferulate, posses...

Field-scale evaluation of biological uranium reduction and reoxidation in the near-source zone at the NABIR Field Research Center in Oak Ridge, TN

International Nuclear Information System (INIS)

Craig S. Criddle; Peter Kitanidis; Scott Fendorf; Weimin Wu; Philip M. Jardine; Jizhong Zhou; Baohua Gu

2006-01-01

The primary objective of the project is to advance the understanding and predictive capability of coupled hydrological, geochemical, and microbiological processes that control the in situ transport and bioremediation radionuclides and co-contaminants at multiple scales. Specific objectives include: (1) Investigate the feasibility of in situ bioremediation of uranium in a highly contaminated region within the subsurface of Area 3 of the DoE ERSP FRC (2) Using a variety of tracer strategies, develop and model a system that establishes hydraulic control of the target region for biostimulation (3) Perform long term in situ biostimulation studies that create a microbial communities capable of reducing residual nitrate to N2 and mobile U(VI) to sparingly soluble U(IV) (4) Use a variety of solid and solution phase interrogation techniques to quantify the extent of in situ reduction and immobilization of U(VI). (5) Investigate a variety of geochemical factors that influence the stability and possible reoxidation of reduced uranium

Friendship in inclusive physical education.

Science.gov (United States)

Seymour, Helena; Reid, Greg; Bloom, Gordon A

2009-07-01

Social interaction and development of friendships between children with and without a disability are often proposed as potential outcomes of inclusive education. Physical activity specialists assert that exercise and sport environments may be conducive to social and friendship outcomes. This study investigated friendship in inclusive physical education from the perspective of students with (n = 8) and without (n = 8) physical disabilities. All participants attended a reversely integrated school and were interviewed using a semistructured, open-ended format. An adapted version of Weiss, Smith, and Theeboom's (1996) interview guide exploring perceptions of peer relationships in the sport domain was used. Four conceptual categories emerged from the analysis: development of friendship, best friend, preferred physical activities and outcomes, and dealing with disability. The results demonstrated the key characteristics of best friends and the influential role they play.

Modification of oxide inclusions in calcium-treated Al-killed high sulphur steels

NARCIS (Netherlands)

Gollapalli, Veerababu; Rao, M.B.Venkata; Karamched, P.S.; Borra, C.R.; Roy, G.G.; Srirangam, Prakash

2018-01-01

A study has been carried out to understand the modification of alumina inclusions in Al-killed high sulphur steel with calcium treatment. For calcium treatment to be effective, a general practice is to desulphurise the steel to prevent the formation of solid CaS inclusions that are harmful to

Thermal-gradient migration of brine inclusions in salt

International Nuclear Information System (INIS)

Yagnik, S.K.

1982-02-01

It has been proposed that the high level nuclear waste be buried deep underground in a suitable geologic formation. Natural salt deposits have been under active consideration as one of the geologic formations where a nuclear waste repository may be built in future. The salt deposits, however, are known to contain a small amount (about 0.5 vol.%) of water in the form of brine inclusions which are dispersed throughout the medium. The temperature gradients imposed by the heat generating nuclear waste will mobilize these brine inclusions. It is important to know the rate and the amount of brine accumulating at the waste packages to properly evaluate the performance of a nuclear waste repository. An extensive experimental investigation of the migration velocities of brine inclusions in synthetic single crystals of NaCl and in polycrystalline natural salt crystals has been conducted. The results show that in a salt repository the brine inclusions within a grain would move with the diffusion controlled velocities. The brine reaching a grain boundary may be swept across, if the thermal gradient is high enough. Grain boundaries in polycrystalline rock salt are apparently quite weak and open up due to drilling the hole for a waste canister and to the thermal stresses which accompany the thermal gradient produced by the heat generating waste. The enhanced porosity allows the water reaching the grain boundary to escape by a vapor transport process

First Ti-XANES analyses of refractory inclusions from Murchison

International Nuclear Information System (INIS)

Simon, S.B.; Sutton, S.R.; Grossman, L.

2009-01-01

Ti valence in refractory phases is an important recorder of redox conditions in the early solar nebula. We report the valence of Ti in pyroxene, spinel and hibonite in spinel-hibonite and spinel-pyroxene inclusions and in a coarse hibonite grain. A system of solar composition is so reducing that Ti 3+ and Ti 4+ can coexist, making the valence of Ti a valuable indicator of f O2 conditions during formation of nebular materials. The Ti 3+ /Ti 4+ ratios observed in the Ti-rich phases fassaite and rhoenite in coarse-grained refractory inclusions from CV3 chondrites have been shown to be quantitatively consistent with formation in a gas of solar composition (log f O2 = IW-6.8), but these are the only objects in chondrites for which this is the case. Here, we report the valence of Ti in various phases in refractory inclusions from the Murchison CM2 chondrite. The second-highest temperature, major-element-bearing phase predicted to condense from a gas of solar composition, hibonite (ideally CaAl 12 O 19 ), can contain significant amounts of Ti, but the hibonite structure can have oxygen vacancies, so calculation of Ti valence from stoichiometry of electron probe analyses is not recommended for hibonite. To date, the only reported measurement of Ti valence in meteoritic hibonite was done by electron spin resonance, on coarse crystals from a Murchison hibonite-perovskite-melilite inclusion. Spinel and most of the pyroxene in CM inclusions contain too little Ti for derivation of Ti 3+ /Ti 4+ ratios from electron probe analyses. X-ray absorption near edge spectroscopy (XANES), however, allows determination of Ti valence in relatively Ti-poor phases. In the present work, we apply synchrotron microXANES to a large hibonite grain from Murchison and to spinel-hibonite (sp-hib) and spinel-pyroxene (sp-pyx) inclusions from Murchison, refractory materials whose Ti 3+ /Ti 4+ ratios have not been previously measured. Analysis of these samples allows comparison of Ti valence of (1

New insights on the spectrophotometric determination of melatonin pKa values and melatonin-βCD inclusion complex formation constant

Science.gov (United States)

Zafra-Roldán, A.; Corona-Avendaño, S.; Montes-Sánchez, R.; Palomar-Pardavé, M.; Romero-Romo, M.; Ramírez-Silva, M. T.

2018-02-01

Using UV-Vis spectrophotometry a stability study of melatonin at different pH values was done in aqueous media, finding that at acidic pH melatonin is unstable when interacting with the environment, however it becomes stable protecting it from light and oxygen. From the UV-Vis spectra and SQUAD software, melatonin pKa values, in a completely protected aqueous medium, were estimated as 5.777 ± 0.011 and 10.201 ± 0.024. Using the same techniques, the melatonin and β-cyclodextrin inclusion complex formation constants were assessed at pH 3, 7 and 11.5, giving the values of log β = (3.07 ± 0.06), (2.94 ± 0.01) and (3.07 ± 0.06) M- 1, respectively. From the global acidity formation constants and the complexes' formation constants, the molar fractions were determined for each species of MT and MT - βCD, to build the molar fraction-[βCD]-pH 3D diagram and the molar fraction-pH 2D diagrams, where it was possible to observe the predominance of the MT species with and without βCD. A voltammetric study at pH 3, allowed obtaining a value of log β = (3.15 ± 0.01) M- 1, which corroborates that obtained through UV-Vis spectrophotometry, supporting strongly the rationale behind using simple, straightforward techniques.

Effective interactions between inclusions in an active bath

Science.gov (United States)

Zaeifi Yamchi, Mahdi; Naji, Ali

2017-11-01

We study effective two- and three-body interactions between non-active colloidal inclusions in an active bath of chiral or non-chiral particles, using Brownian dynamics simulations within a standard, two-dimensional model of disk-shaped inclusions and active particles. In a non-chiral active bath, we first corroborate previous findings on effective two-body repulsion mediated between the inclusions by elucidating the detailed non-monotonic features of the two-body force profiles, including a primary maximum and a secondary hump at larger separations that was not previously reported. We then show that these features arise directly from the formation, and sequential overlaps, of circular layers (or "rings") of active particles around the inclusions, as the latter are brought to small surface separations. These rings extend to radial distances of a few active-particle radii from the surface of inclusions, giving the hard-core inclusions relatively thick, soft, repulsive "shoulders," whose multiple overlaps then enable significant (non-pairwise) three-body forces in both non-chiral and chiral active baths. The resulting three-body forces can even exceed the two-body forces in magnitude and display distinct repulsive and attractive regimes at intermediate to large self-propulsion strengths. In a chiral active bath, we show that, while active particles still tend to accumulate at the immediate vicinity of the inclusions, they exhibit strong depletion from the intervening region between the inclusions and partial depletion from relatively thick, circular zones further away from the inclusions. In this case, the effective, predominantly repulsive interactions between the inclusions turn to active, chirality-induced, depletion-type attractions, acting over an extended range of separations.

Study on vitamin K 3-cyclodextrin inclusion complex and analytical application

Science.gov (United States)

Zhenming, Dong; Xiuping, Liu; Guomei, Zhang; Shaomin, Shuang; Jinghao, Pan

2003-07-01

The inclusion interaction of the complexes between Vitamin K3 (VK3) and β-cyclodextrin (β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD) and sulfobutylether-β-cyclodextrin (SBE-β-CD) were studied by using steady-state fluorescence measurements. The various factors affecting the inclusion process were examined in detail. The formation constants and inclusion stoichiometry for VK3-CDs were determined. The results showed that the inclusion ability of β-CD and its derivatives was the order: SBE-β-CD>HP-β-CD>β-CD. The related inclusion mechanism is proposed to explain the inclusion process. A method of determining VK3 was established with the linear range was 2.5×10-6-5.0×10-4 M, and was used to determine the VK3 tablets. The recoveries were in the range of 97.52-103.5%. The results were satisfactory.

Below-surface analysis of inclusions with PIXE and PIGE

International Nuclear Information System (INIS)

MacArthur, J.D.; Ma, X.P.; Palmer, G.R.; Anderson, A.J.; Clark, A.H.

1990-01-01

The composition of fluid inclusions in host minerals holds much information about the chemical environment of mineral formation. When solid inclusions are exposed through polishing, their content can readily be investigated with an electron or proton probe. However, with an electron probe, only the daughter minerals or the residue material left when a fluid inclusion is opened can be analyzed since electrons with energies of tens of keV cannot penetrate to the unexposed inclusion. On the other hand, proton beams of a few MeV can penetrate a few tens of μm of material and still be able to excite characteristic radiation. This phenomenon has been exploited for the analysis of subsurface inclusions. Ideally, standard petrographic sections are polished to that inclusions, targetted for analysis, are brought to within 10 μm of the surface. The overlying matrix reduces the sensitivity of PIXE for the elements of low Z such as Na and Al because of the attenuation of the X-rays. However, these elements, as well as elements of even lower Z, which cannot be analyzed with the electron probe, can readily be detected with PIGE at good sensitivity. (orig.)

Theoretical investigation of inclusion complex formation of Gold (III – Dimethyldithiocarbamate anticancer agents with cucurbit[n = 5,6]urils

Directory of Open Access Journals (Sweden)

Zabiollah Mahdavifar

2014-09-01

Full Text Available Gold (III-N,N-dimethyldithiocarbamate [DMDT(AuX2] complexes have recently gained increasing attention as potential anticancer agents because of their strong tumor cell growth–inhibitory effects, generally achieved by exploiting non-cisplatin-like mechanisms of action. The goal of our research work is to encapsulate the gold(III dimethyldithiocarbamate complexes as anticancer with cucurbit[n]urils (CB[n = 5, 6] by accurate calculations, to predict the inclusion complex formation of gold(III species with cucurbiturils (CB[n = 5, 6]. The calculations were carried out just for the 1:1 stoichiometric complexes. Upon encapsulation, binding energy, thermodynamic parameters, structural parameters and electronic structures of complexes are investigated. The results of the thermodynamic calculations and the binding energy show that the inclusion process is exothermic and the CB[6]/[DMDT(AuBr2] complex is more stable than other complexes. The final geometry of CB[n]/drugs indicates that the drugs were expelled from the cavity of CB[n]. NBO calculations reveal that the hydrogen bonding between CB[n] and drugs and electrostatic interactions are the major factors contributing to the overall stabilities of the complexes.

Exploring inclusion complexes of ionic liquids with α- and β- cyclodextrin by NMR, IR, mass, density, viscosity, surface tension and conductance study

Science.gov (United States)

Barman, Biraj Kumar; Rajbanshi, Biplab; Yasmin, Ananya; Roy, Mahendra Nath

2018-05-01

The formation of the host-guest inclusion complexes of ionic liquids namely [BMIm]Cl and [HMIm]Cl with α-CD and β-CD were studied by means of physicochemical and spectroscopic methods. Conductivity and surface tension study were in good agreement with the 1H NMR and FT-IR studies which confirm the formation of the inclusion complexes. The Density and viscosity study also supported the formation of the ICs. Further the stoichiometry was determined 1:1 for each case and the association constants and thermodynamic parameters derived supported the most feasible formation of the [BMIm]Cl- β-CD inclusion complex.

40Ar/39Ar laser-probe dating of diamond inclusions from the Premier kimberlite

International Nuclear Information System (INIS)

Phillips, D.; Onstott, T.C.; Harris, J.W.; Strathclyde Univ., Glasgow

1989-01-01

Inclusions encapsulated by diamonds at the time of their formation provide a means for determining diamond crystallization ages and the chemistry of the surrounding upper mantle at that time. Sm-Nd studies of peridotitic inclusions, from Cretaceous-age kimberlites in southern Africa, suggest that the diamonds formed 3.3 Gyr ago. By contrast, eclogite-suite inclusions generally yield younger ages, sometimes approaching the time of kimberlite eruption. Here we report the results of 40 Ar/ 39 Ar laser-probe analyses of individual eclogitic clinopyroxene inclusions from Premier diamonds, which yield a mean age of 1,198±14 Myr. This age agrees well with Sm-Nd and 40 Ar/ 39 Ar analyses on similar Premier inclusions, and is indistinguishable from the inferred time of emplacement of the host kimberlite (1,150-1,230 Myr), which implies that diamond formation was essentially synchronous with kimberlite generation. The extrapolated non-radiogenic 40 Ar/ 36 Ar ratio of 334±102 is similar to the present-day atmospheric composition. This value is inconsistent with Sr and Nd isotopic signatures from Premier eclogite inclusions, which suggest a depleted mantle source ( 40 Ar/ 36 Ar>20,000). Pre-entrapment equilibration of the inclusions with an 36 Ar-rich fluid is the most probable explanation for the low non-radiogenic ( 40 Ar/ 36 Ar) composition. (author)

In vitro folding of inclusion body proteins.

Science.gov (United States)

Rudolph, R; Lilie, H

1996-01-01

Insoluble, inactive inclusion bodies are frequently formed upon recombinant protein production in transformed microorganisms. These inclusion bodies, which contain the recombinant protein in an highly enriched form, can be isolated by solid/liquid separation. After solubilization, native proteins can be generated from the inactive material by using in vitro folding techniques. New folding procedures have been developed for efficient in vitro reconstitution of complex hydrophobic, multidomain, oligomeric, or highly disulfide-bonded proteins. These protocols take into account process parameters such as protein concentration, catalysis of disulfide bond formation, temperature, pH, and ionic strength, as well as specific solvent ingredients that reduce unproductive side reactions. Modification of the protein sequence has been exploited to improve in vitro folding.

Ar-39/Ar-40 systematics of Allende inclusions

International Nuclear Information System (INIS)

Herzog, G.F.; Rutgers University, New Brunswick, NJ); Bence, A.E.

1980-01-01

A laser microprobe was used to measure the Ar isotopic contents of individual mineral grains in four neutron-irradiated Allende samples: two coarse-grained Ca-Al-rich inclusions, one fine-grained Ca-Al-rich inclusion, and one sample with matrix and miscellaneous chondrules. The following K-Ar ages (G.y.) were obtained after degassing low Ar retentive sites by preheating the samples for one hour at 675 C: matrix, 3.5 + or - 0.2 three miscellaneous chondrules, 4.4 + or - 0.1, 4.0 + or - 0.1, and 4.4 + or - 0.1 and the fine-grained inclusion, 4.5 + or - 0.2. The minerals in the coarse-grained Ca-Al-rich inclusions have ubiquitous chlorine, less than 10 ppm K and apparent ages ranging upwards from 4.6 G.y. to well over 10 G.y. Possible explanations for these apparent ages are atmospheric contamination, the decay of K-40 prior to the formation of the solar system, and the trapping of radiogenic Ar-40 lost by the matrix

Some additional observations on inclusions in the granitic rocks of the Sierra Nevada

Science.gov (United States)

Dodge, F.C.W.; Kistler, R.W.

1990-01-01

Microgranular quartz diorite and diorite inclusions are widespread in central Sierra Nevada granitoid rocks and are almost exclusively restricted to hornblende-bearing rocks, most commonly felsic tonalites and mafic granodiorites. The Nd-Sm and Rb-Sr systematics indicate that most inclusions were in isotopic equilibrium with enclosing materials at the time of formation. Silica contents of inclusions and granitoids are contiguous, but inclusions generally contain less than, and granitoids more than, 60% SiO2. Ferric oxide and H2O+ trends relative to SiO2 suggests many inclusions formed as concentrations of hydrous mafic minerals. Variation of other major element oxides and trace elements support this inference. Most inclusions represent fragmented crystal accumulations of early-formed, near-liquidus minerals generated from these previously mixed magmas. -from Authors

Measuring Nurse Educators' Willingness to Adopt Inclusive Teaching Strategies.

Science.gov (United States)

Levey, Janet A

The purpose of the study was to examine the characteristics and relationships of nurse educators' teaching practices, knowledge, support, and willingness to adopt inclusive teaching strategies (WillAdITS). Adopting more inclusive teaching strategies based on universal design for instruction is an innovative way for educators to reach today's diverse student body. However, the pedagogy has not diffused into nursing education. Descriptive statistics and hierarchical multiple regression were used for analyzing data from 311 nurse educators in prelicensure and RN to BSN programs. The model explained 44.8 percent of the variance in WillAdITS. The best indicators for this pedagogy were knowledge of universal design for instruction, social system support for inclusive teaching strategies, multiple instructional formats, and years of teaching. Knowing factors influencing the adoption of inclusive teaching strategies can inform schools of nursing of areas needing further development in the preparation of novice to experienced educators to teach diverse learners.

Historical Background of Inclusive Education Development in the Nordic Countries

Directory of Open Access Journals (Sweden)

Natalia Andriichuk

2017-06-01

Full Text Available The article analyzes and interprets the comprehensive presentation of the development of inclusive education in some Nordic countries, namely Sweden, Norway and Iceland. The article states that the special education is still an alternative form of education for children with special needs who cannot attend secondary schools in the majority of the countries. Thus, the relation between inclusive and special education allows the author to draw some parallels between these two types of study to trace the transition from one to another. The author concludes that the history of inclusive education formation in Sweden, Norway and Iceland has much in common, but the Icelandic education system has characteristics which distinguish it from the two others.

The electrochemical behaviour study of La3+ ion in fused chlorides bath. The LaNi5 formation

International Nuclear Information System (INIS)

Dias, Cristiane

2002-01-01

The electrochemical behaviour of La 3+ ion was studied in fused chlorides bath, with purpose to obtain LaNi 5 formation parameters. The lanthanum reduction/reoxidation mechanism and intermetallic compound formation were investigated by cyclic voltammetry, chronopotentiommetry and galvanostatic electrodeposition. The electrolyte employed was eutectic mixture NaCl-KCl (1:1) with anhydrous LaCl 3 as solute, since 0,25 mol. L -1 up to 2 mol. L -1 , between 700 deg C and 800 deg C. The anhydrous LaCl 3 was prepared by lanthanum chloride slow dehydration with HCl flow and heating until 300 deg C. Over molybdenum, results depicted that lanthanum electrochemical behaviour was quasi-reversible and electrodeposition occurred in a charge transfer step with three electrons. In nickel, intermetallic compound formation was observed by interdiffusion. The scanning electronic microscopy (SEM-EDS) and X ray diffraction analysis indicated that layers composition depend on temperature and solute concentration in fused bath. Mainly LaNi 5 intermetallic compound was formed with LaCl 3 anhydrous concentration of 2 mol. L -1 at 750 deg C, with cathodic current density until 100 mA.cm -2 . (author)

Preparation, characterization, and thermal stability of β-cyclodextrin/soybean lecithin inclusion complex.

Science.gov (United States)

Wang, Xinge; Luo, Zhigang; Xiao, Zhigang

2014-01-30

β-Cyclodextrin (β-CD), which is widely used to increase the stability, solubility, and bioavailability of guests, can form host-guest inclusion complexes with a wide variety of organic molecules. In this study the β-CD/soybean lecithin inclusion complex was prepared. The effect of reaction parameters such as reaction temperature, reaction time and the molar ratio of β-CD/soybean lecithin on inclusion ratio were studied. The inclusion ratio of the product prepared under the optimal conditions of β-CD/soybean lecithin molar ratio 2:1, reaction temperature 60°C reaction time 2h was 40.2%. The results of UV-vis, DSC, XRD and FT-IR spectrum indicated the formation of inclusion complex. The thermal stability experiment indicated that the thermal stability of soybean lecithin in inclusion complex was significantly improved compared with free soybean lecithin. Copyright © 2013 Elsevier Ltd. All rights reserved.

Formation of active inclusion bodies induced by hydrophobic self-assembling peptide GFIL8.

Science.gov (United States)

Wang, Xu; Zhou, Bihong; Hu, Weike; Zhao, Qing; Lin, Zhanglin

2015-06-16

In the last few decades, several groups have observed that proteins expressed as inclusion bodies (IBs) in bacteria could still be biologically active when terminally fused to an appropriate aggregation-prone partner such as pyruvate oxidase from Paenibacillus polymyxa (PoxB). More recently, we have demonstrated that three amphipathic self-assembling peptides, an alpha helical peptide 18A, a beta-strand peptide ELK16, and a surfactant-like peptide L6KD, have properties that induce target proteins into active IBs. We have developed an efficient protein expression and purification approach for these active IBs by introducing a self-cleavable intein molecule. In this study, the self-assembling peptide GFIL8 (GFILGFIL) with only hydrophobic residues was analyzed, and this peptide effectively induced the formation of cytoplasmic IBs in Escherichia coli when terminally attached to lipase A and amadoriase II. The protein aggregates in cells were confirmed by transmission electron microscopy analysis and retained ~50% of their specific activities relative to the native counterparts. We constructed an expression and separation coupled tag (ESCT) by incorporating an intein molecule, the Mxe GyrA intein. Soluble target proteins were successfully released from active IBs upon cleavage of the intein between the GFIL8 tag and the target protein, which was mediated by dithiothreitol. A variant of GFIL8, GFIL16 (GFILGFILGFILGFIL), improved the ESCT scheme by efficiently eliminating interference from the soluble intein-GFIL8 molecule. The yields of target proteins at the laboratory scale were 3.0-7.5 μg/mg wet cell pellet, which is comparable to the yields from similar ESCT constructs using 18A, ELK16, or the elastin-like peptide tag scheme. The all-hydrophobic self-assembling peptide GFIL8 induced the formation of active IBs in E. coli when terminally attached to target proteins. GFIL8 and its variant GFIL16 can act as a "pull-down" tag to produce purified soluble proteins with

Characterization of intracellular inclusions in the urothelium of mice exposed to inorganic arsenic.

Science.gov (United States)

Dodmane, Puttappa R; Arnold, Lora L; Muirhead, David E; Suzuki, Shugo; Yokohira, Masanao; Pennington, Karen L; Dave, Bhavana J; Lu, Xiufen; Le, X Chris; Cohen, Samuel M

2014-01-01

Inorganic arsenic (iAs) is a known human carcinogen at high exposures, increasing the incidences of urinary bladder, skin, and lung cancers. In most mammalian species, ingested iAs is excreted mainly through urine primarily as dimethylarsinic acid (DMA(V)). In wild-type (WT) mice, iAs, DMA(V), and dimethylarsinous acid (DMA(III)) exposures induce formation of intramitochondrial urothelial inclusions. Arsenite (iAs(III)) also induced intranuclear inclusions in arsenic (+3 oxidation state) methyltransferase knockout (As3mt KO) mice. The arsenic-induced formation of inclusions in the mouse urothelium was dose and time dependent. The inclusions do not occur in iAs-treated rats and do not appear to be related to arsenic-induced urothelial cytotoxicity. Similar inclusions in exfoliated urothelial cells from humans exposed to iAs have been incorrectly identified as micronuclei. We have characterized the urothelial inclusions using transmission electron microscopy (TEM), DNA-specific 4',6-diamidino-2-phenylindole (DAPI), and non-DNA-specific Giemsa staining and determined the arsenical content. The mouse inclusions stained with Giemsa but not with the DAPI stain. Analysis of urothelial mitochondrial- and nuclear-enriched fractions isolated from WT (C57BL/6) and As3mt KO mice exposed to arsenate (iAs(V)) for 4 weeks showed higher levels of iAs(V) in the treated groups. iAs(III) was the major arsenical present in the enriched nuclear fraction from iAs(V)-treated As3mt KO mice. In conclusion, the urothelial cell inclusions induced by arsenicals appear to serve as a detoxifying sequestration mechanism similar to other metals, and they do not represent micronuclei.

Role of the disaggregase ClpB in processing of proteins aggregated as inclusion bodies.

Science.gov (United States)

Zblewska, Kamila; Krajewska, Joanna; Zolkiewski, Michal; Kędzierska-Mieszkowska, Sabina

2014-08-01

Overproduction of heterologous proteins in bacterial systems often results in the formation of insoluble inclusion bodies (IBs), which is a major impediment in biochemical research and biotechnology. In principle, the activity of molecular chaperones could be employed to gain control over the IB formation and to improve the recombinant protein yields, but the potential of each of the major bacterial chaperones (DnaK/J, GroEL/ES, and ClpB) to process IBs has not been fully established yet. We investigated the formation of inclusion bodies (IBs) of two aggregation-prone proteins, VP1LAC and VP1GFP, overproduced in Escherichiacoli in the presence and absence of the chaperone ClpB. We found that both ClpB isoforms, ClpB95 and ClpB80 accumulated in E. coli cells during the production of IBs. The amount of IB proteins increased in the absence of ClpB. ClpB supported the resolubilization and reactivation of the aggregated VP1LAC and VP1GFP in E. coli cells. The IB disaggregation was optimal in the presence of both ClpB95 and ClpB80. Our results indicate an essential role of ClpB in controlling protein aggregation and inclusion body formation in bacteria. Copyright © 2014 Elsevier Inc. All rights reserved.

Effects of shape and size of inclusions on the sintering of ZnO-ZrO2 composites

International Nuclear Information System (INIS)

Nakada, Yohsuke; Kimura, Toshio

1997-01-01

The densification behavior and microstructure development of ZnO matrices containing rigid ZrO 2 inclusions were studied, with special emphasis on the effect of inclusion shape and size. The inclusions retarded the densification of the matrix, regardless of the inclusion shape and size. For large inclusions with diameter of > 10 microm, dense regions developed between inclusion particles. The inclusion particles and dense regions formed a continuous network, which constrained the densification of the composites. The inclusion shape had a small effect on the development of dense regions. Severe retardation in densification was observed for compacts containing inclusions with diameters of < 10 microm. In these cases, dense regions between inclusion particles did not develop. The formation of the continuous network cannot be applicable to small inclusions as an origin of retardation of densification

Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies.

Science.gov (United States)

Schipper-Krom, Sabine; Juenemann, Katrin; Jansen, Anne H; Wiemhoefer, Anne; van den Nieuwendijk, Rianne; Smith, Donna L; Hink, Mark A; Bates, Gillian P; Overkleeft, Hermen; Ovaa, Huib; Reits, Eric

2014-01-03

Neurodegenerative disorders such as Huntington's disease are hallmarked by neuronal intracellular inclusion body formation. Whether proteasomes are irreversibly recruited into inclusion bodies in these protein misfolding disorders is a controversial subject. In addition, it has been proposed that the proteasomes may become clogged by the aggregated protein fragments, leading to impairment of the ubiquitin-proteasome system. Here, we show by fluorescence pulse-chase experiments in living cells that proteasomes are dynamically and reversibly recruited into inclusion bodies. As these recruited proteasomes remain catalytically active and accessible to substrates, our results challenge the concept of proteasome sequestration and impairment in Huntington's disease, and support the reported absence of proteasome impairment in mouse models of Huntington's disease. Copyright © 2013 Federation of European Biochemical Societies. All rights reserved.

Studies on inclusion complex as potential systems for enhancement of oral bioavailability of olmesartan medoxomil

Directory of Open Access Journals (Sweden)

Hetal Paresh Thakkar

2012-01-01

Full Text Available Background: Olmesartan medoxomil (OLM, an anti-hypertensive agent administered orally, has absolute bioavailability of only 26% due to the poor aqueous solubility (7.75 μg/ml. Inclusion complexation with cyclodextrins (CD has been reported to increase the aqueous solubility of various compounds. Aim: The present investigation aimed to enhancing the oral bioavailability of OLM by inclusion complexation with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD. Materials and Methods: The inclusion complexes with HP-β-CD were prepared using two different methods, viz., physical mixture and kneading. The prepared complexes were characterized for various parameters such as drug content, aqueous solubility, dissolution study, in vitro diffusion, intestinal permeability and stability study. The formation of the inclusion complex was confirmed by differential scanning calorimetry, X-ray diffraction, and Fourier transform infrared spectroscopy. Results: The solubility, dissolution, diffusion rate, and intestinal permeability of the prepared complexes were found to be significantly higher than that of the plain drug. Among the two methods used for formation of inclusion complex, KN method gave higher solubility rates and hence is a better method when compared with PM. Conclusion: The approach seems to be promising in improving the oral bioavailability of OLM.

Production, Characterization, and Stability of Orange or Eucalyptus Essential Oil/β-Cyclodextrin Inclusion Complex.

Science.gov (United States)

Kringel, Dianini Hüttner; Antunes, Mariana Dias; Klein, Bruna; Crizel, Rosane Lopes; Wagner, Roger; de Oliveira, Roberto Pedroso; Dias, Alvaro Renato Guerra; Zavareze, Elessandra da Rosa

2017-11-01

The aim of this study was to produce and characterize inclusion complexes (IC) between β-cyclodextrin (β-CD) and orange essential oil (OEO) or eucalyptus essential oil (EEO), and to compare these with their pure compounds and physical mixtures. The samples were evaluated by chemical composition, morphology, thermal stability, and volatile compounds by static headspace-gas chromatography (SH-GC). Comparing the free essential oil and physical mixture with the inclusion complex, of both essential oils (OEO and EEO), it was observed differences occurred in the chemical composition, thermal stability, and morphology. These differences show that there was the formation of the inclusion complex and demonstrate the necessity of the precipitation method used to guarantee the interaction between β-CD and essential oils. The slow loss of the volatile compounds from both essential oils, when complexed with β-CD, showed a higher stability when compared with their physical mixtures and free essential oils. Therefore, the results showed that the chemical composition, molecular size, and structure of the essential oils influence the characteristics of the inclusion complexes. The application of the β-CD in the formation of inclusion complexes with essential oils can expand the potential applications in foods. © 2017 Institute of Food Technologists®.

Numerical simulation of convection and inclusion distribution during solidification in a heavy steel ingot

International Nuclear Information System (INIS)

Lin, Rui; Shen, Houfa

2015-01-01

Inclusions content in the steel ingot is an important index for homogeneity, and it becomes more serious for heavy steel ingots which are used for major equipment. However, knowledge about the formation of inclusion in steel ingot is limited, and modeling of inclusion distribution is still challenging, so it is of great significance to research the behavior of inclusion. In this paper, fluid flow during solidification is numerically simulated based on the equilibrium equations of mass, momentum and energy, and then inclusion distribution is modeled according to the Lagrangian Stokes trajectory method. The Results show that the inclusion distribution in the steel ingot is influenced by the flow pattern which is affected by the solidification pattern. Therefore, inclusion distribution could be controlled by the solidification front with the optimization of heat transfer condition such as the hot top design of steel ingot for the high quality steel production. (paper)

Importin-α7 Is Involved in the Formation of Ebola Virus Inclusion Bodies but Is Not Essential for Pathogenicity in Mice.

Science.gov (United States)

Gabriel, Gülsah; Feldmann, Friederike; Reimer, Rudolph; Thiele, Swantje; Fischer, Meike; Hartmann, Enno; Bader, Michael; Ebihara, Hideki; Hoenen, Thomas; Feldmann, Heinz

2015-10-01

Ebola virus (EBOV) protein 24 antagonizes the host interferon (IFN) response by hijacking select nuclear importin-α isoforms. Thereby, it blocks STAT1-mediated IFN-α/β and IFN-γ synthesis. However, owing to the lack of importin-α knockout animal models in the past, their role in EBOV pathogenesis remained largely unknown. Here, we demonstrate that importin-α7 is involved in the formation of EBOV inclusion bodies and replication. However, deletion of the gene encoding importin-α7 was not sufficient to increase survival rates among mice infected with EBOV. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Preparation, characterization and in vitro dissolution study of Nitrazepam: Cyclodextrin inclusion complex

OpenAIRE

Patel, J. S.; Patel, R. P.

2012-01-01

The objectives of this research were to prepare and characterize inclusion complexes of Nitrazepam with Hydroxypropyl-β-cyclodextrin (HPβCD) and Sulfobutyl ether β-cyclodextrin (SBEβCD) to study the effect of complexation on the dissolution rate of Nitrazepam, a water-insoluble drug. The phase solubility profile of Nitrazepam with Hydroxypropyl- β-cyclodextrin and Sulfobutyl ether β-cyclodextrin was an AP-type, indicating the formation of 2:1 stoichiometric inclusion complexes. Gibbs free ene...

Mg isotope evidence for contemporaneous formation of chondrules and refractory inclusions

DEFF Research Database (Denmark)

Bizzarro, Martin; Baker, J.A.; Haack, Henning

2004-01-01

Primitive or undifferentiated meteorites (chondrites) date back to the origin of the Solar System, and thus preserve a record of the physical and chemical processes that occurred during the earliest evolution of the accretion disk surrounding the young Sun. The oldest Solar System materials present...... within these meteorites are millimetre- to centimetre-sized calcium-aluminium-rich inclusions (CAIs) and ferromagnesian silicate spherules (chondrules), which probably originated by thermal processing of pre-existing nebula solids. Chondrules are currently believed to have formed ~2-3 million years (Myr...

Confronting New Demands : Inclusive Growth, Inclusive Trade ...

International Development Research Centre (IDRC) Digital Library (Canada)

Confronting New Demands : Inclusive Growth, Inclusive Trade. Policymakers, businesspeople and civil society advocates need evidence-based research to react ... understood implications, such as labour standards and intellectual property; ...

Developing a financial inclusion index and inclusive growth in India

OpenAIRE

Susanta Kumar SETHY

2016-01-01

Financial inclusion is one of the systems through which Inclusive Growth can be achieved in developing countries like India where large sections are unable or hopeless to contribute in the financial system. An inclusive financial system mobilizes more resources for productive purposes leading to higher economic growth, better opportunities and reduction of poverty. This study, proposed an Index of financial inclusion – a multidimensional measure. The Financial Inclusion Index c...

Inclusion Characteristics and Acicular Ferrite Nucleation in Ti-Containing Weld Metals of X80 Pipeline Steel

Science.gov (United States)

Wang, Bingxin; Liu, Xianghua; Wang, Guodong

2018-06-01

X80 steel weld metals with Ti contents of 0.003 to 0.13 pct were prepared by the single-pass submerged-arc welding process. The effects of Ti content in weld metals on the constituent phases of inclusions and chemical compositions of the constituent phases, as well as the potency of acicular ferrite (AF) nucleation on the inclusions were investigated. Moreover, the crystallographic orientation relationship between the AF and inclusion was examined. The results show that with an increase in Ti content, the primary constituent phases of the inclusions change from the (Mn-Al-Si-O) compound to a mixture of spinel and pseudobrookite solid solutions, and eventually to pseudobrookite. The spinel solid solution is characterized by the MnTi2O4 constituent. Compared to pseudobrookite, spinel has a lower Ti concentration, but a significantly higher Mn content. In the case of the presence of a considerable amount of spinel, the Mn element is enriched strongly in the inclusions, resulting in the development of a Mn-depleted zone (MDZ) in the matrix around the inclusions, which enhances the driving force for AF formation. AF shows the Baker-Nutting orientation relationship with MnTi2O4. The formation of MDZ and the presence of the Baker-Nutting orientation relationship promote the ability of inclusions to nucleate the intragranular AF.

Study of Te Inclusion and Related Point Defects in THM-Growth CdMnTe Crystal

Science.gov (United States)

Mao, Yifei; Zhang, Jijun; Min, Jiahua; Liang, Xiaoyan; Huang, Jian; Tang, Ke; Ling, Liwen; Li, Ming; Zhang, Ying; Wang, Linjun

2018-02-01

This study establishes a model for describing the interaction between Te inclusions, dislocations and point defects in CdMnTe crystals. The role of the complex environment surrounding the formation of Te inclusions was analyzed. Images of Te inclusions captured by scanning electron microscope and infrared microscope were used to observe the morphology of Te inclusions. The morphology of Te inclusions is discussed in light of crystallography, from the crystal growth temperature at 900°C to the melting temperature of Te inclusions using the traveling heater method. The dislocation nets around Te inclusions were calculated by counting lattice mismatches between the Te inclusions and the bulk CdMnTe at 470°C. The point defects of Te antisites were found to be gathered around Te inclusions, with dislocation climb during the cooling phase of crystal growth from 470°C to room temperature. The Te inclusions, dislocation nets and surrounding point defects are considered to be an entirety for evaluating the effect of Te inclusions on CdMnTe detector performance, and an effective mobility-lifetime product (μτ) was obtained.

Lipotoxicity induces hepatic protein inclusions through TBK1-mediated p62/SQSTM1 phosphorylation.

Science.gov (United States)

Cho, Chun-Seok; Park, Hwan-Woo; Ho, Allison; Semple, Ian A; Kim, Boyoung; Jang, Insook; Park, Haeli; Reilly, Shannon; Saltiel, Alan R; Lee, Jun Hee

2017-12-18

Obesity commonly leads to hepatic steatosis, which often provokes lipotoxic injuries to hepatocytes that cause non-alcoholic steatohepatitis (NASH). NASH in turn is associated with the accumulation of insoluble protein aggregates that are composed of ubiquitinated proteins and ubiquitin adaptor p62/sequestosome 1 (SQSTM1). The formation of p62 inclusions in hepatocytes is the critical marker that distinguishes simple fatty liver from NASH and predicts a poor prognostic outcome for subsequent liver carcinogenesis. However, the molecular mechanism by which lipotoxicity induces protein aggregation is currently unknown. Here we show that upon saturated fatty acid-induced lipotoxicity, Tank-binding protein kinase 1 (TBK1) is activated and phosphorylates p62. The TBK1-mediated p62 phosphorylation is important for lipotoxicity-induced aggregation of ubiquitinated proteins and the formation of large protein inclusions in hepatocytes. In addition, cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING), upstream regulators of TBK1, are involved in the lipotoxic activation of TBK1 and subsequent p62 phosphorylation in hepatocytes. Furthermore, TBK1 inhibition prevented formation of the ubiquitin-p62 aggregates, not only in cultured hepatocytes, but also in mouse models of obesity and NASH. These results suggest that lipotoxic activation of TBK1 and subsequent p62 phosphorylation are critical steps in the NASH pathology of protein inclusion accumulation in hepatocytes. This mechanism can provide an explanation for how hypernutrition and obesity promote the development of severe liver pathologies, such as steatohepatitis and liver cancer, by facilitating the formation of p62 inclusions. This article is protected by copyright. All rights reserved. © 2017 by the American Association for the Study of Liver Diseases.

Host-guest chemistry of dendrimer-drug complexes: 7. Formation of stable inclusions between acetylated dendrimers and drugs bearing multiple charges.

Science.gov (United States)

Fang, Min; Zhang, Jiahai; Wu, Qinglin; Xu, Tongwen; Cheng, Yiyun

2012-03-15

Drug molecules bearing multiple charges usually form precipitates with cationic dendrimers, which presents a challenge during the preparation of dendrimer inclusions for these drugs. In the present study, fully acetylated polyamidoamine (PAMAM) dendrimers were proposed as stable vehicles for drug molecules bearing two negative charges such as Congo red and indocyanine green. NMR techniques including (1)H NMR and (1)H-(1)H NOESY were used to characterize the host-guest chemistry of acetylated dendrimer and these guest molecules. The cationic PAMAM dendrimer was found to form a precipitate with Congo red and indocyanine green, but the acetylated one avoided the formation of cross-linking structures in aqueous solutions. NOESY studies revealed the encapsulation of Congo red and indocyanine green within the interior cavities of PAMAM dendrimers at mild acidic conditions and acetylated dendrimers show much stronger ability to encapsulate the guest molecules than cationic ones. Also, UV-vis-NIR studies suggest that acetylated dendrimers significantly improve the photostability of indocyanine green and prevent the formation of indocyanine green J-aggregates in aqueous solutions. The present study provides a new insight into dendrimer-based host-guest systems, especially for those guest molecules bearing multiple charges. © 2012 American Chemical Society

Genesis of diamond inclusions: An integrated cathodoluminescence (CL) and Electron backscatter diffraction (EBSD) study on eclogitic and peridotitic inclusions and their diamond host.

Science.gov (United States)

van den Heuvel, Quint; Matveev, Sergei; Drury, Martyn; Gress, Michael; Chinn, Ingrid; Davies, Gareth

2017-04-01

Diamond inclusions are potentially fundamental to understanding the formation conditions of diamond and the volatile cycles in the deep mantle. In order to fully understand the implications of the compositional information recorded by inclusions it is vital to know whether the inclusions are proto-, syn-, or epigenetic and the extent to which they have equilibrated with diamond forming fluids. In previous studies, the widespread assumption was made that the majority of diamond inclusions are syngenetic, based upon observation of cubo-octahedral morphology imposed on the inclusions. Recent work has reported the crystallographic relationship between inclusions and the host diamond to be highly complex and the lack of crystallographic relationships between inclusions and diamonds has led some to question the significance of imposed cubo-octahedral morphology. This study presents an integrated EBSD and CL study of 9 diamonds containing 20 pyropes, 2 diopsides, 1 forsterite and 1 rutile from the Jwaneng and Letlhakane kimberlite clusters, Botswana. A new method was developed to analyze the crystallographic orientation of the host diamond and the inclusions with EBSD. Diamonds plates were sequentially polished to expose inclusions at different levels in the diamond. CL imaging at different depths was performed in order to produce a 3D view of diamond growth zones around the inclusions. Standard diamond polishing techniques proved too aggressive for silicate inclusions as they were damaged to such a degree that EBSD measurements on the inclusions were impossible. The inclusions were milled with a Ga+ focused ion beam (FIB) at a 12° angle to clean the surface for EBSD measurements. Of the 24 inclusions, 9 have an imposed cubo-octahedral morphology. Of these inclusions, 6 have faces orientated parallel to diamond growth zones and/or appear to have nucleated on a diamond growth surface, implying syngenesis. In contrast, other diamonds record resorption events such that

Protein recovery from inclusion bodies of Escherichia coli using mild solubilization process.

Science.gov (United States)

Singh, Anupam; Upadhyay, Vaibhav; Upadhyay, Arun Kumar; Singh, Surinder Mohan; Panda, Amulya Kumar

2015-03-25

Formation of inclusion bodies in bacterial hosts poses a major challenge for large scale recovery of bioactive proteins. The process of obtaining bioactive protein from inclusion bodies is labor intensive and the yields of recombinant protein are often low. Here we review the developments in the field that are targeted at improving the yield, as well as quality of the recombinant protein by optimizing the individual steps of the process, especially solubilization of the inclusion bodies and refolding of the solubilized protein. Mild solubilization methods have been discussed which are based on the understanding of the fact that protein molecules in inclusion body aggregates have native-like structure. These methods solubilize the inclusion body aggregates while preserving the native-like protein structure. Subsequent protein refolding and purification results in high recovery of bioactive protein. Other parameters which influence the overall recovery of bioactive protein from inclusion bodies have also been discussed. A schematic model describing the utility of mild solubilization methods for high throughput recovery of bioactive protein has also been presented.

Fluid inclusion study of the Witwatersrand gold-uranium ores

International Nuclear Information System (INIS)

Shepherd, T.J.

1977-01-01

Fluid inclusions, preserved in quartz pebbles of the uraniferous and auriferous Precambrian oligomictic conglomerates of the Witwatersrand Basin, provide a unique insight into the genesis of the ores. Using differences in inclusion characteristics in conjunction with intra- and inter-deformational textures for adjacent pebbles, a distinction is made between pre- and post-depositional inclusions. Excluding those related to subsequent brittle fracture, the former comprise five principal types; two of which are distinguished by the development of liquid carbon dioxide. Collectively they indicate a moderate to high pressure-temperature environment of vein quartz formation. Systematic variation in the relative abundance of these inclusion assemblages for different sections of the orefield demonstrates the importance of well-defined provenance areas or multiple entry points into the basins. A marked sympathetic relationship between uraniferous banket ores and the presence of vein quartz rich in liquid carbon dioxide inclusions, together with a corresponding antipathetic relationship for gold, strongly suggests separate sources for the metals. The temporal and spatial aspects of the association 'U-CO 2 ' also imply a uranium influx into the basin from discrete areas of the hinterland contemporaneous with the sediments. Post-depositional inclusions are subordinate and offer no support for the alternative epigenetic model and show only a later interaction of relatively cool circulating groundwaters. A discussion is given of the probable nature and origin of uranium in the source rocks and its mode of transportation. In conclusion, a proposal is made for the use of applied fluid inclusion research in the evaluation of and exploration for similar deposits. (author)

Characterisation of Catfish (Clarias Batrachus) Oil: β-Cyclodextrin Inclusion Complex

International Nuclear Information System (INIS)

Zaibunnisa Abdul Haiyee; Nor Izzatul Adyani Yahya; Norizzah Abd Rashid; Dzulkifly Mat Hashim

2016-01-01

Catfish is a cheap source of essential omega-3 fatty acids especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Catfish oil was extracted and clean-up using pressurised liquid extraction (PLE) from the viscera of catfish (Clarias batrachus). However, the characteristics of catfish oils are sticky, strong fishy odour and can easily be oxidised with short shelf-life. In this study, catfish oil was converted into powder by formation of inclusion complex with β-cyclodextrin. Inclusion complex was prepared by using co-precipitation and kneading methods and compared with physical mixture. The inclusion complex formed were characterised by using field emission scanning electron microscopy (FESEM), differential scanning calorimeter (DSC) and fourier transform infrared spectroscopy (FTIR). FESEM images revealed that inclusion complex using co-precipitation and kneading methods has smaller in crystal sizes and appeared as different morphology compared to physical mixture. DSC proved that co-precipitation method was able to form new solid phase due to shifting of melting point to higher temperature (145.22 degree Celcius). FTIR supported the result by proving strengthening of carbonyl group (C=O). Therefore, co-precipitation method was able to successfully produce inclusion complex of catfish oil, β-cyclodextrin. (author)

Formation of disorder aluminium zones in an immiscible lead-aluminium system

International Nuclear Information System (INIS)

Huang, R Z; Zhang, L H; Sui, M L; Wang, Y M

2004-01-01

High resolution transmission electron microscopy (HRTEM) observations show evidence for the formation of disorder Al zones around some faceted Pb inclusions embedded in an Al matrix in immiscible lead-aluminium samples, which were prepared by a melt-spun method and then aged for about two months at room temperature. Furthermore, it is found that, both before and after ageing, all such Pb inclusions have a cube-cube orientation relationship with the Al matrix. The results of molecular dynamics (MD) simulations give an extensive analysis of the formation of the disorder Al zones and provide a reasonable explanation for the HRTEM finding: the existence of oxygen soluted in the Pb inclusions at higher temperatures may lead to the formation of the disorder Al zone in the aged sample. The dependence of the thickness of the disorder Al zone on the amount of oxygen soluted in the Pb inclusion at higher temperatures, and the average stress in the equilibrium configuration of a MD cell, is discussed

Fluids in the Siilinjärvi carbonatite complex, eastern Finland: Fluid inclusion evidence for the formation conditions of zircon and apatite

Directory of Open Access Journals (Sweden)

Poutiainen, M.

1995-06-01

Full Text Available In the studied zircon and apatite crystals, data recorded two different compositional types of fluid inclusions: Type 1 H2O-CO2, low salinity inclusions (XCO2 = 0.42 to 0.87; XNaCl = 0.001 to 0.005 with bulk densities of 0.73 to 0.87 g/cm3, and Type 2 H2O moderate salinity (XNaCl = 0.03 to 0.06 inclusions with densities of 0.83 to 1.02 g/cm3. The Type 1 inclusions are not present in apatite. In zircon, the observed fluid inclusion types occur in separate domains: around (Type 1 and outside (Type 2 the apparent core. Fluid inclusions are further subdivided into pseudosecondary and secondary inclusions. Using a combination of SEM-EDS, optical characteristics and crushing-stage, various daughter and captive minerals were identified. The fluid inclusion data suggest that the pseudosecondary Type 1 and Type 2 inclusions in zircon and apatite were trapped during the pre-emplacement evolution of the carbonatite at mid-crustal conditions (P≥4 kbar, T≥625°C. The Type 1 fluid was depleted in CO2, during crystal fractionation and cooling leading to a fluid phase enriched in water and alkalies. Fenitization was obviously induced by these saline aqueous fluids. During emplacement of the carbonatite to the present level, zircon phenocrysts were intensively fractured, some Type 1 inclusions were re-equilibrated, and multiphase Type 2 inclusions were trapped. It is assumed that all these inclusions in zircon and the pseudosecondary Type 2 inclusions in apatite have a magmatic origin. In apatite, calcite inclusions occur side-by-side with the secondary Type 2 inclusions. These calcites co-existed with the aqueous fluid during fracturing and metamorphic re-crystallization of apatites. Probably, this metamorphic fluid also is responsible for the transport and deposition of at least some of the calcite at low temperatures (200-350°C.

Bacterial formation of phosphatic laminites off Peru.

Science.gov (United States)

Arning, E T; Birgel, D; Brunner, B; Peckmann, J

2009-06-01

Authigenic phosphatic laminites enclosed in phosphorite crusts from the shelf off Peru (10 degrees 01' S and 10 degrees 24' S) consist of carbonate fluorapatite layers, which contain abundant sulfide minerals including pyrite (FeS(2)) and sphalerite (ZnS). Low delta(34)S(pyrite) values (average -28.8 per thousand) agree with bacterial sulfate reduction and subsequent pyrite formation. Stable sulfur isotopic compositions of sulfate bound in carbonate fluorapatite are lower than that of sulfate from ambient sea water, suggesting bacterial reoxidation of sulfide by sulfide-oxidizing bacteria. The release of phosphorus and subsequent formation of the autochthonous phosphatic laminites are apparently caused by the activity of sulfate-reducing bacteria and associated sulfide-oxidizing bacteria. Following an extraction-phosphorite dissolution-extraction procedure, molecular fossils of sulfate-reducing bacteria (mono-O-alkyl glycerol ethers, di-O-alkyl glycerol ethers, as well as the short-chain branched fatty acids i/ai-C(15:0), i/ai-C(17:0) and 10MeC(16:0)) are found to be among the most abundant compounds. The fact that these molecular fossils of sulfate-reducing bacteria are distinctly more abundant after dissolution of the phosphatic laminite reveals that the lipids are tightly bound to the mineral lattice of carbonate fluorapatite. Moreover, compared with the autochthonous laminite, molecular fossils of sulfate-reducing bacteria are: (1) significantly less abundant and (2) not as tightly bound to the mineral lattice in the other, allochthonous facies of the Peruvian crusts consisting of phosphatic coated grains. These observations confirm the importance of sulfate-reducing bacteria in the formation of the phosphatic laminite. Model calculations highlight that organic matter degradation by sulfate-reducing bacteria has the potential to liberate sufficient phosphorus for phosphogenesis.

Photo-induced reduction of flavin mononucleotide in aqueous solutions

International Nuclear Information System (INIS)

Song, S.-H.; Dick, B.; Penzkofer, A.

2007-01-01

The photo-induced reduction of flavin mononucleotide (FMN) in aqueous solutions is studied by absorption spectra measurement under aerobic and anaerobic conditions. Samples without exogenous reducing agent and with the exogenous reducing agents ethylene-diamine-tetraacetic acid (EDTA) and dithiothreitol (DTT) are investigated. Under anaerobic conditions the photo-induced reduction with and without reducing agents is irreversible. Under aerobic conditions the photo-reduction without added reducing agent is small compared to the photo-degradation, and the photo-reduction of FMN by the reducing agents is reversible (re-oxidation in the dark). During photo-excitation of FMN the dissolved oxygen is consumed by singlet oxygen formation and subsequent chemical reaction. After light switch-off slow re-oxidation (slow absorption recovery) occurs due to air in-diffusion from surface. EDTA degradation by FMN excitation leads to oxygen scavenging. The quantum efficiencies of photo-reduction under aerobic and anaerobic conditions are determined. The re-oxidation of reduced FMN under aerobic conditions and due to air injection is investigated

The Origin and Evolution of Nucleosynthetic Sr Isotope Variability in Calcium and Aluminum-rich Refractory Inclusions

Science.gov (United States)

Myojo, Kunihiro; Yokoyama, Tetsuya; Okabayashi, Satoki; Wakaki, Shigeyuki; Sugiura, Naoji; Iwamori, Hikaru

2018-01-01

Nucleosynthetic isotope anomalies in meteorites are useful for investigating the origin of materials in the protoplanetary disk and dynamical processes of planetary formation. In particular, calcium and aluminum-rich inclusions (CAIs) found in chondrites are key minerals for decoding the initial conditions of the solar system before the accretion of small planetary bodies. In this study, we report isotopic analyses for three Allende CAIs, fluffy type A (FTA), type B, and fine-grained spinel rich (FS) inclusions, with a specific emphasis on the measurements of 84Sr/86Sr ratios. It was found that the average μ 84Sr values (106 relative deviations from a standard material) were 175, 129, and 56 ppm for the samples of FTA, type B, and FS inclusions, respectively. Additionally, the FTA samples exhibited heterogeneous μ 84Sr values, while those for the type B and FS inclusions were homogeneous within individual inclusions. The elevated μ 84Sr values were most likely explained by the relative enrichment of r-process nuclides in the CAI formation region. The variation of μ 84Sr values between the FTA and type B inclusions, as well as within the FTA inclusion, suggests the presence of multiple CAI source reservoirs with distinct isotopic compositions, which is either inherited from isotopic heterogeneity in the molecular cloud or caused by the selective destruction of r-process-enriched supernova grains via nebular thermal processing. On the other hand, the reaction between a refractory precursor of the FS inclusion and a gaseous reservoir enriched in Mg, Si, and 16O resulted in the lowest μ 84Sr values for the FS inclusion.

Silica-coated magnetic nanoparticles impair proteasome activity and increase the formation of cytoplasmic inclusion bodies in vitro

Science.gov (United States)

Phukan, Geetika; Shin, Tae Hwan; Shim, Jeom Soon; Paik, Man Jeong; Lee, Jin-Kyu; Choi, Sangdun; Kim, Yong Man; Kang, Seong Ho; Kim, Hyung Sik; Kang, Yup; Lee, Soo Hwan; Mouradian, M. Maral; Lee, Gwang

2016-01-01

The potential toxicity of nanoparticles, particularly to neurons, is a major concern. In this study, we assessed the cytotoxicity of silica-coated magnetic nanoparticles containing rhodamine B isothiocyanate dye (MNPs@SiO2(RITC)) in HEK293 cells, SH-SY5Y cells, and rat primary cortical and dopaminergic neurons. In cells treated with 1.0 μg/μl MNPs@SiO2(RITC), the expression of several genes related to the proteasome pathway was altered, and proteasome activity was significantly reduced, compared with control and with 0.1 μg/μl MNPs@SiO2(RITC)-treated cells. Due to the reduction of proteasome activity, formation of cytoplasmic inclusions increased significantly in HEK293 cells over-expressing the α–synuclein interacting protein synphilin-1 as well as in primary cortical and dopaminergic neurons. Primary neurons, particularly dopaminergic neurons, were more vulnerable to MNPs@SiO2(RITC) than SH-SY5Y cells. Cellular polyamines, which are associated with protein aggregation, were significantly altered in SH-SY5Y cells treated with MNPs@SiO2(RITC). These findings highlight the mechanisms of neurotoxicity incurred by nanoparticles. PMID:27378605

Online analysis of protein inclusion bodies produced in E. coli by monitoring alterations in scattered and reflected light.

Science.gov (United States)

Ude, Christian; Ben-Dov, Nadav; Jochums, André; Li, Zhaopeng; Segal, Ester; Scheper, Thomas; Beutel, Sascha

2016-05-01

The online monitoring of recombinant protein aggregate inclusion bodies during microbial cultivation is an immense challenge. Measurement of scattered and reflected light offers a versatile and non-invasive measurement technique. Therefore, we investigated two methods to detect the formation of inclusion bodies and monitor their production: (1) online 180° scattered light measurement (λ = 625 nm) using a sensor platform during cultivation in shake flask and (2) online measurement of the light reflective interference using a porous Si-based optical biosensor (SiPA). It could be shown that 180° scattered light measurement allows monitoring of alterations in the optical properties of Escherichia coli BL21 cells, associated with the formation of inclusion bodies during cultivation. A reproducible linear correlation between the inclusion body concentration of the non-fluorescent protein human leukemia inhibitory factor (hLIF) carrying a thioredoxin tag and the shift ("Δamp") in scattered light signal intensity was observed. This was also observed for the glutathione-S-transferase-tagged green fluorescent protein (GFP-GST). Continuous online monitoring of reflective interference spectra reveals a significant increase in the bacterium refractive index during hLIF production in comparison to a non-induced reference that coincide with the formation of inclusion bodies. These online monitoring techniques could be applied for fast and cost-effective screening of different protein expression systems.

Refolding techniques for recovering biologically active recombinant proteins from inclusion bodies.

Science.gov (United States)

Yamaguchi, Hiroshi; Miyazaki, Masaya

2014-02-20

Biologically active proteins are useful for studying the biological functions of genes and for the development of therapeutic drugs and biomaterials in a biotechnology industry. Overexpression of recombinant proteins in bacteria, such as Escherichia coli, often results in the formation of inclusion bodies, which are protein aggregates with non-native conformations. As inclusion bodies contain relatively pure and intact proteins, protein refolding is an important process to obtain active recombinant proteins from inclusion bodies. However, conventional refolding methods, such as dialysis and dilution, are time consuming and, often, recovered yields of active proteins are low, and a trial-and-error process is required to achieve success. Recently, several approaches have been reported to refold these aggregated proteins into an active form. The strategies largely aim at reducing protein aggregation during the refolding procedure. This review focuses on protein refolding techniques using chemical additives and laminar flow in microfluidic chips for the efficient recovery of active proteins from inclusion bodies.

Refolding Techniques for Recovering Biologically Active Recombinant Proteins from Inclusion Bodies

Directory of Open Access Journals (Sweden)

Hiroshi Yamaguchi

2014-02-01

Full Text Available Biologically active proteins are useful for studying the biological functions of genes and for the development of therapeutic drugs and biomaterials in a biotechnology industry. Overexpression of recombinant proteins in bacteria, such as Escherichia coli, often results in the formation of inclusion bodies, which are protein aggregates with non-native conformations. As inclusion bodies contain relatively pure and intact proteins, protein refolding is an important process to obtain active recombinant proteins from inclusion bodies. However, conventional refolding methods, such as dialysis and dilution, are time consuming and, often, recovered yields of active proteins are low, and a trial-and-error process is required to achieve success. Recently, several approaches have been reported to refold these aggregated proteins into an active form. The strategies largely aim at reducing protein aggregation during the refolding procedure. This review focuses on protein refolding techniques using chemical additives and laminar flow in microfluidic chips for the efficient recovery of active proteins from inclusion bodies.

[In vitro renaturation of proteins from inclusion bodies].

Science.gov (United States)

Porowińska, Dorota; Marszałek, Ewelina; Wardęcka, Paulina; Komoszyński, Michał

2012-06-11

Recombinant proteins and enzymes are commonly used in many areas of our life, such as diagnostics, industry and medicine, due to heterologous synthesis in prokaryotic expression systems. However, a high expression level of foreign protein in bacteria cells results in formation of inactive and insoluble aggregates--inclusion bodies. Reactivation of aggregated proteins is a complex and time-consuming process. Every protein requires experimental optimization of the process conditions. The choice of the refolding method depends on the type of recombinant protein and its physical, chemical and biological properties. Recovery of the activity of proteins accumulated in inclusion bodies can be divided into 4 steps: 1) inclusion bodies isolation, 2) solubilization of aggregates, 3) renaturation, 4) purification of catalytically active molecules. Efficiency of the refolding process depends on many physical factors and chemical and biological agents. The above parameters determine the time of the folding and prevent protein aggregation. They also assist the folding and have an influence on the solubility and stability of native molecules. To date, dilution, dialysis and chromatography are the most often used methods for protein refolding.

No Stone Left Unturned: Exploring the Convergence of New Capitalism in Inclusive Education in the U.S.

Science.gov (United States)

Waitoller, Federico R.; Kozleski, Elizabeth B.

2015-01-01

This paper examines how inclusive education reform is appropriated when New Capitalism work practices dominate the discourse of school improvement in an urban school. We asked how New Capitalism mediates the formation of a professional vision for inclusive education. Using analytical tools from Critical Discourse Analysis (CDA), we analyzed…

Inclusive production of large-p/sub T/ protons and quark-quark elastic scattering

International Nuclear Information System (INIS)

Chen, C.K.

1978-01-01

A proton-formation process in combination with hard quark-quark scattering is capable of explaining the observed large-p/sub T/ single-proton inclusive production data. This model implies that the inclusive production of two large-p/sub T/ protons at opposite directions is dominated by large-angle elastic scattering of two up quarks, and becomes an ideal place to study elastic quark-quark scattering. This two-proton inclusive production process is also ideal for the study of the spin structure of quark-quark elastic scattering, so the assumptions of pure vector-type quark-quark interaction and of colored quarks can be checked empirically. The consistency of applying the quark-elastic-scattering idea to large-angle elastic proton-proton scattering and to the inclusive production of large-p/sub T/ protons is also demonstrated

Formation of poly(ethylene glycol) inclusion complexes in aqueous solutions of mixed cyclodextrins

Czech Academy of Sciences Publication Activity Database

Horský, Jiří; Walterová, Zuzana

2003-01-01

Roč. 203, - (2003), s. 259-264 ISSN 1022-1360. [International Conference on Polymer-Solvent Complexes and Intercalates /4./. Prague, 22.07.2002-25.07.2002] R&D Projects: GA AV ČR IAA1050101 Institutional research plan: CEZ:AV0Z4050913 Keywords : cyclodextrins * inclusion complexes * phase separation Subject RIV: BO - Biophysics Impact factor: 0.895, year: 2003

Laboratory Study on Prevention of CaO-Containing ASTM "D-Type" Inclusions in Al-Deoxidized Low-Oxygen Steel Melts During Basic Slag Refining

Science.gov (United States)

Jiang, Min; Wang, Xin-Hua; Yang, Die; Lei, Shao-Long; Wang, Kun-Peng

2015-12-01

Present work was attempted to explore the possibility of preventing CaO-containing inclusions in Al-deoxidized low-oxygen special steel during basic slag refining, which were known as ASTM D-type inclusions. Based on the analysis on formation thermodynamics of CaO-containing inclusions, a series of laboratory experiments were designed and carried out in a vacuum induction furnace. During the experiments, slag/steel reaction equilibrium was intentionally suppressed with the aim to decrease the CaO contents in inclusions, which is different from ordinary concept that slag/steel reaction should be promoted for better control of inclusions. The obtained results showed that high cleanliness of steel was obtained in all the steel melts, with total oxygen contents varied between 0.0003 and 0.0010 pct. Simultaneously, formation of CaO-containing inclusions was successfully prohibited, and all the formed oxide inclusions were MgO-Al2O3 or/and Al2O3 in very small sizes of about 1 to 3 μm. And 90 pct to nearly 98 pct of them were wrapped by relative thicker MnS outer surface layers to produce dual-phased "(MgO-Al2O3) + MnS" or "Al2O3 + MnS" complex inclusions. Because of much better ductility of MnS, certain deformability of these complex inclusions can be expected which is helpful to improve fatigue resistance property of steel. Only very limited number of singular MnS inclusions were with sizes larger than 13 μm, which were formed during solidification because of. In the end, formation of oxide inclusions in steel was qualitatively evaluated and discussed.

Assistive Technology for an Inclusive Society for People with Intellectual Disability.

Science.gov (United States)

Owuor, John; Larkan, Fiona

2017-01-01

People with intellectual disability (ID), are some of the most stigmatized and marginalized social groups. Ongoing global initiatives such as the United Nations Convention on the Rights of Persons with Disabilities (UNCPD) and Strategic Development Goals (SDGs) aim to accelerate their inclusion into the society. In many high-income countries, deinstitutionalization of care for people with ID forms part of the broader social inclusion agenda for people with ID into the society. Access to appropriate assistive technology (AT) can mediate the ongoing normalization/inclusion efforts for people with ID. AT can enable users with ID to access societal processes such as education, employment, socialization or independent living. Effective use of AT can also enhance the formation and/or maintenance of interpersonal relationships by people with ID, thus promote their social support.

Approaching Inclusion as Social Practice: Processes of Inclusion and Exclusion

DEFF Research Database (Denmark)

Molbæk, Mette; Hansen, Janne Hedegaard; Lassen, Mikkel

2018-01-01

The article presents the results of a review of international research investigating mechanisms and processes of inclusion and exclusion as an ongoing part of social practice in a school context. The review forms part of a research project investigating the social practices of inclusive education...... in primary and lower-secondary education (age 6–16) in public schools as constituted by processes of inclusion and exclusion. The project aims to shift the scientific focus of research in inclusive education from the development of pedagogical and didactic practice to the importance of community construction...... through inclusion and exclusion processes. The project arises in context of Danish education policy, while the review looked for international research findings on the limits between inclusion and exclusion: how they are drawn, by whom, for what reasons, and for whose benefit? On the background...

Inclusões intracelulares associadas à "espiga branca" do trigo Intracellular inclusions associated with white spike disease of wheat

Directory of Open Access Journals (Sweden)

E. W. Kitajima

1971-05-01

Full Text Available Fragmentos da epiderme inferior de fôlhas de trigo com sintomas típicos da anomalia conhecida como "espiga branca", examinados ao microscópio convencional, mostraram a constante ocorrência de inclusões intracelulares, de dimensões avantajadas e de aspecto fibrilar e enovelado. Freqüentemente, células adjacentes aquelas que continham inclusões apresentavam formações aciculares, em seu interior. Seções ultrafinas dessas folhas, examinadas ao microscópio electrô-nico, revelaram que tais inclusões eram de localização citoplasmática e formadas por uma massa de partículas filamentosas de 7-10 m¼ em diâmetro e de comprimento indeterminado, idênticas àquelas encontradas em preparações "leaf dip". Várias alterações celulares, como hipertrofia do nucléolo, degeneração dos cloroplastos e vesicularização do retículo endoplasmático, puderam também ser notadas. Ocasionalmente, formações cristalinas foram notadas na periferia e mesmo no interior do núcleo. A semelhança das inclusões citoplasmáticas e das partículas que as compõem, com aquelas descritas, associadas à infecção do vírus da "hoja blanca" do arroz, e também o fato de o trigo desenvolver sintomas do tipo espiga branca quando inoculado experimentalmente com o vírus da "hoja blanca", parecem reforçar a sugestão de que a espiga branca do trigo teria etiologia virosa e que o agente causal seria do grupo do vírus da "hoja blanca" do arroz. A constante associação das inclusões celulares com a condição de espiga branca, em trigo, constitui mais um elemento para sua rápida diagnose.Light microscopic examination of epidermal strips from leaves of wheat (Triticum sativumL. showing typical symptoms of the white spike (WS disease, demonstrated the constant occurrence of huge, fibrous and whorled intracellular inclusions. Occasionally cells adjacent to those having inclusions contained needle-like formations. The whorled inclusions appeared in ultrathin

Limits to Inclusion

Science.gov (United States)

Hansen, Janne Hedegaard

2012-01-01

In this article, I will argue that a theoretical identification of the limit to inclusion is needed in the conceptual identification of inclusion. On the one hand, inclusion is formulated as a vision that is, in principle, limitless. On the other hand, there seems to be an agreement that inclusion has a limit in the pedagogical practice. However,…

Inclusive Business - What It Is All About? Managing Inclusive Companies

Directory of Open Access Journals (Sweden)

Tea Golja

2012-01-01

Full Text Available Following the challenges we face today, the inclusive business models are future business models through which the Millennium Development Goals can be fostered and strengthen. These are the models which, through their strategic orientation on inclusivity, include low income communities in their value chain. This can be done through combining variety of strategies which all have two common points – recognition of stakeholders and adjustment of the product to the target market. The paper presents the analysis of inclusive markets. Hence, the research results show the dispersion of inclusive businesses worldwide, type of the organization, sector coverage, and contribution to MDGs as well as the particular way of inclusion of low income communities in their value chain. The aim is to present how inclusive business benefits not only the low income societies, but the companies that operate in this way as well.

Dynamic effective properties of heterogeneous geological formations with spherical inclusions under periodic time variations

Science.gov (United States)

Rabinovich, A.; Dagan, G.; Miloh, T.

2013-04-01

In unsteady groundwater flow (or similar processes of heat/electrical conduction), the heterogeneous medium structure is characterized by two random properties, the conductivity K and the specific storativity S. The average head field ⟨H ⟩and the associated effective properties Kef, Sef are determined for a layer with a periodic head drop between boundaries, such that H is periodic in time, and a medium made up of a matrix with a dilute concentration of spherical inclusions. In the common quasi-steady approximation, Kef is equal to the classical steady solution while Sef = SA, the arithmetic mean. We derive expressions for the frequency dependent Kef, Sef, which are generally complex, i.e., dynamic. The main result is the delineation of the ranges of the parameters: dimensionless frequency (ω) and contrasts of conductivity (κ) and storativity (s) between the matrix and the inclusions, for which dynamic effects are significant.

Designing Inclusive Systems Designing Inclusion for Real-world Applications

CERN Document Server

Clarkson, John; Robinson, Peter; Lazar, Jonathan; Heylighen, Ann

2012-01-01

The Cambridge Workshops on Universal Access and Assistive Technology (CWUAAT) are a series of workshops held at a Cambridge University College every two years. The workshop theme: “Designing inclusion for real-world applications” refers to the emerging potential and relevance of the latest generations of inclusive design thinking, tools, techniques, and data, to mainstream project applications such as healthcare and the design of working environments. Inclusive Design Research involves developing tools and guidance enabling product designers to design for the widest possible population, for a given range of capabilities. There are five main themes: •Designing for the Real-World •Measuring Demand And Capabilities •Designing Cognitive Interaction with Emerging Technologies •Design for Inclusion •Designing Inclusive Architecture In the tradition of CWUAAT, we have solicited and accepted contributions over a wide range of topics, both within individual themes and also across the workshop’s scope. ...

Molybdenite in calcium-aluminum-rich inclusions in the Allende meteorite

Science.gov (United States)

Fuchs, L. H.; Blander, M.

1977-01-01

The first observations of molybdenite in a meteorite have been made in two Ca-Al-rich inclusions in the Allende chondrite. The mineral occurs as single individuals completely enclosed in high Ni metal (62-64.5 wt. % Ni). The association with refractories is consistent with thermodynamic calculations which predict that Mo is a high temperature condensate even when nucleation constraints are imposed on the formation of a metal phase. Kinetic factors (including nucleation constraints) appear to have played an important role in the formation of molybdenite and the associated sulfides, magnetite and high nickel metal.

Inclusion complex of amiodarone hydrochloride with cyclodextrins: preparation, characterization and dissolution rate evaluation

Directory of Open Access Journals (Sweden)

Alexandre Machado Rubim

2017-06-01

Full Text Available ABSTRACT This study aimed to improve the water solubility of amiodarone hydrochloride (AMH via inclusion complexes with β-cyclodextrin, methyl-β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin. Inclusion complexes were developed by physical mixture, coevaporation, spray-drying and freeze-drying. Solid state analysis was performed using X-ray powder diffraction, differential scanning calorimetry and scanning electronic microscopy. Thermodynamic studies demonstrate that the inclusion complexes of drug into different cyclodextrins were an exothermic process that occurred spontaneously. Water solubility and drug dissolution rates were significantly increased after the formation of inclusion complexes with the cyclodextrins evaluated in relation to the physical mixture and pure drug. The present study provides useful information for the potential application of complexation with amiodarone HCl. This may be a good strategy for the development of solid pharmaceutical dosage forms.

Gas chromatographic analysis of volatiles in fluid and gas inclusions

Science.gov (United States)

Andrawes, F.; Holzer, G.; Roedder, E.; Gibson, E.K.; Oro, John

1984-01-01

Most geological samples and some synthetic materials contain fluid inclusions. These inclusions preserve for us tiny samples of the liquid and/or the gas phase that was present during formation, although in some cases they may have undergone significant changes from the original material. Studies of the current composition of the inclusions provide data on both the original composition and the change since trapping.These inclusions are seldom larger than 1 millimeter in diameter. The composition varies from a single major compound (e.g., water) in a single phase to a very complex mixture in one or more phases. The concentration of some of the compounds present may be at trace levels.We present here some analyses of inclusions in a variety of geological samples, including diamonds. We used a sample crusher and a gas chromatography—mass spectrometry (GC—MS) system to analyze for organic and inorganic volatiles present as major to trace constituents in inclusions. The crusher is a hardened stainless-steel piston cylinder apparatus with tungsten carbide crusing surfaces, and is operated in a pure helium atmosphere at a controlled temperature.Samples ranging from 1 mg to 1 g were crushed and the released volatiles were analyzed using multi-chromatographic columns and detectors, including the sensitive helium ionization detector. Identification of the GC peaks was carried out by GC—MS. This combination of procedures has been shown to provide geochemically useful information on the process involved in the history of the samples analyzed.

Fluid inclusion characteristics and geological significance of the Dajinshan W-Sn polymetallic deposit in Yunfu, Guangdong Province

Science.gov (United States)

Yu, Zhangfa; Chen, Maohong; Zhao, Haijie

2015-05-01

The Dajinshan tungsten-tin polymetallic deposit is a quartz-vein-type ore deposit located in Western Guangdong Province. The ore bodies show a fairly simple shape and mainly occur as tungsten-tin polymetallic-bearing sulfide quartz veins, including quartz vein, quartz-greisens, and sulfide quartz veins, and their distribution is spatially related to Dajinshan granitoids. The formation of the deposit experienced three stages: a wolframite-molybdenite-quartz stage, a wolframite-cassiterite-sulfide-quartz stage, and a fluorite-calcite-carbonate stage. Based on detailed petrographic observations, we conducted microthermometric and Raman microspectroscopic studies of fluid inclusions formed at different ore-forming stages in the Dajinshan tungsten-tin polymetallic deposit, identifying four dominant types of fluid inclusions: aqueous two-phase inclusions, CO2-bearing inclusions, solid or daughter mineral-bearing inclusions, and gas-rich inclusions. The gas compositions of ore-forming fluids in the Dajinshan tungsten-tin polymetallic deposit are mostly CO2, CH4, and H2O. The hydrogen, oxygen, and sulfur isotopic data imply that the ore-forming fluids in the Dajinshan tungsten-tin polymetallic deposit were mainly derived from magmatic fluids, mixed with meteoric water in the ore-formation process. These results indicate that the fluid mixing and boiling led to the decomposition of the metal complex in ore-forming fluids and ore deposition.

A large planetary body inferred from diamond inclusions in a ureilite meteorite.

Science.gov (United States)

Nabiei, Farhang; Badro, James; Dennenwaldt, Teresa; Oveisi, Emad; Cantoni, Marco; Hébert, Cécile; El Goresy, Ahmed; Barrat, Jean-Alix; Gillet, Philippe

2018-04-17

Planetary formation models show that terrestrial planets are formed by the accretion of tens of Moon- to Mars-sized planetary embryos through energetic giant impacts. However, relics of these large proto-planets are yet to be found. Ureilites are one of the main families of achondritic meteorites and their parent body is believed to have been catastrophically disrupted by an impact during the first 10 million years of the solar system. Here we studied a section of the Almahata Sitta ureilite using transmission electron microscopy, where large diamonds were formed at high pressure inside the parent body. We discovered chromite, phosphate, and (Fe,Ni)-sulfide inclusions embedded in diamond. The composition and morphology of the inclusions can only be explained if the formation pressure was higher than 20 GPa. Such pressures suggest that the ureilite parent body was a Mercury- to Mars-sized planetary embryo.

Thermal gradient brine inclusion migration in salt study: gas-liquid inclusions, preliminary model

International Nuclear Information System (INIS)

Olander, D.R.; Machiels, A.J.

1979-10-01

Natural salt deposits contain small cubical inclusions of brine distributed through the salt. Temperature gradients, resulting from storing heat-generating wastes in the salt, can cause the inclusions to move through the salt. Prediction of the rate and amount of brine-inclusion migration is necessary for the evaluation of bedded or domed salts as possible media for waste repositories. Inclusions filled exclusively with liquid migrate up the temperature gradient towards the heat source. The solubility of salt in the brine inclusion increases with temperature. Consequently, salt dissolves into the inclusion across the hot surface and crystallizes out at the cold surface. Diffusion of salt within the liquid phase from the hot to the cold faces causes the inclusions to move in the opposite direction. In so doing, they change shape and eventually become rectangular parallelipipeds with a width (dimension perpendicular to the thermal gradient) much larger than the thickness (dimension in the direction of the thermal gradient). The inclusions may also contain a gas phase predominantly consisting of water vapor. These entities are termed two-phase or gas-liquid inclusions. The two-phase inclusions usually migrate down the temperature gradient away from the heat source remaining more-or-less cubical. A two-phase inclusion also forms when an all-liquid inclusion reaches the waste package; upon opening up at the salt-package interface, the brine partially evaporates and the inclusion reseals with some insoluble gas trapped inside. These gas-liquid inclusions proceed to move down the temperature gradient, in the opposite sense of the all-liquid inclusions. The gas-liquid inclusions phenomenon provides a pathway by which radionuclides leached from the wasteform by the brine can be transported away from the waste package and thus might have greater access to the biosphere

Imaged brine inclusions in young sea ice—Shape, distribution and formation timing

DEFF Research Database (Denmark)

Galley, R.J.; Else, B.G.T.; Geilfus, Nicolas-Xavier

2015-01-01

Liquid inclusions in sea ice are variable and dependent on the myriad of physical conditions of the atmosphere– sea ice environment in which the sea ice was grown, and whether or not melting processes affected the sea ice. In that light, there exist relatively few observations and resultant quant...... in the context of the environment in which it grew. Finally, we show that a vertical brine volume distribution profile can be calculated using MR image data, extend- ing the (non-imaging) nuclear magnetic resonance work of others in this vein....

Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis

DEFF Research Database (Denmark)

Nissen, Torben Lauesgaard; Hamann, Claus Wendelboe; Kielland-Brandt, M. C.

2000-01-01

Glycerol is formed as a by-product in production of ethanol and baker's yeast during fermentation of Saccharomyces cerevisiae under anaerobic and aerobic growth conditions, respectively. One physiological role of glycerol formation by yeast is to reoxidize NADH, formed in synthesis of biomass...

Inclusive Education in Italy: Description and Reflections on Full Inclusion

Science.gov (United States)

Anastasiou, Dimitris; Kauffman, James M.; Di Nuovo, Santo

2015-01-01

Inclusion of students with disabilities when appropriate is an important goal of special education for students with special needs. Full inclusion, meaning no education for any child in a separate setting, is held to be desirable by some, and Italy is likely the nation with an education system most closely approximating full inclusion on the…

A combinatorial approach of inclusion complexation and dendrimer synthesization for effective targeting EGFR-TK.

Science.gov (United States)

Shende, Pravin; Patil, Sampada; Gaud, R S

2017-07-01

The aim of the present study was to use a combinatorial approach of inclusion complexation and dendrimer synthesization of gefitinib using solvent-free technique for targeting EGFR-TK to treat Non-Small-Cell Lung Cancer (NSCLC). The inclusion complex of gefitinib with β-cyclodextrin was prepared by trituration method. This complex encapsulated G4 PAMAM dendrimers were synthesized by Michael addition and amidation reactions using green chemistry and then PEGylated by conjugation reaction. FTIR and DSC confirmed the formation of inclusion complex of gefitinib and β-cyclodextrin and PEGylation of G4 PAMAM dendrimers. Gefitinib showed higher solubility, encapsulation efficiency and controlled release profile from PEGylated dendrimers compared to inclusion complex. The PEGylated dendrimers of inclusion complex of gefitinib were found to reduce hemolytic toxicity and lesser GI 50 value on Human lung cancer cell line A-549 by effective targeting EGFR-TK. A combinatorial approach of inclusion complexation and dendrimer synthesization is one of the alternative advanced approaches to treat NSCLC. Copyright © 2017 Elsevier B.V. All rights reserved.

Chemical 3D-imaging of glass inclusions from allende (CV3) olivine via SIMS: A new insight on chondrule formation conditions

Science.gov (United States)

Florentin, L.; Deloule, E.; Faure, F.; Mangin, D.

2018-06-01

Natural glass inclusions - hosted in Mg-rich olivines from Allende (CV3) type I chondrules - and synthetic melt inclusions - trapped in forsterite crystallized from CMAS (CaO-MgO-Al2O3-SiO2) melts - were mapped by Secondary Ion Mass Spectrometry (SIMS) for CMAS major oxides. The first ever 3D chemical images of extra-terrestrial glass inclusions were obtained, along with chemical depth profiles for each oxide. Results show similar patterns for both synthetic glass inclusions (trapped in olivine formed by slow crystallization in a magmatic liquid) and natural inclusions from Allende's olivines. No incompatible-rich boundary layer or diffusion pattern was observed in either case. The absence of an incompatible-rich boundary layer suggests that the olivine overgrowth surrounding glass inclusions in Allende's olivines was formed during slow cooling of the host olivine and likely the surrounding chondrule. This provides new constraints on the cooling rates of type I chondrules.

Formation Mechanism of CaS-Bearing Inclusions and the Rolling Deformation in Al-Killed, Low-Alloy Steel with Ca Treatment

Science.gov (United States)

Xu, Guang; Jiang, Zhouhua; Li, Yang

2016-08-01

The existing form of CaS inclusion in Ca-treated, Al-killed steel during secondary refining process was investigated with scanning electron microscopy and an energy-dispersive spectrometer (EDS). The results of 12 heats industrial tests showed that CaS has two kinds of precipitation forms. One form takes place by the direct reaction of Ca and S, and the other takes place by the reaction of CaO in calcium aluminates with dissolved Al and S in liquid steel. Thermodynamic research for different precipitation modes of CaS under different temperature was carried out. In particular, CaO-Al2O3-CaS isothermal section diagrams and component activities of calcium aluminates were calculated by the thermodynamic software FactSage. By thermodynamic calculation, a precipitation-area diagram of oxide-sulfide duplex inclusion was established by fixing the sulfur content. The quantity of CaS, which was precipitated in a reaction between [Al], [S] and (CaO), can be calculated and predicted based on the precipitation-area diagram of oxide-sulfide duplex inclusion. Electron probe microanalysis and EDS were used for observing rolling deformation of different types of CaS-bearing inclusions during the rolling process. Low modification of calcium aluminates wrapped by CaS has different degrees of harm to steel in the rolling process. A thick CaS layer can prevent some fragile calcium aluminates from being crushed during the rolling process. Some oxide-sulfide duplex inclusion contains little CaS performed better deformation during the rolling process, but when CaS in oxide-sulfide duplex inclusion becomes more, it will cause the whole inclusion to lose plastic yielding ability. The plastic deformation region of CaS-bearing inclusion in a CaO-Al2O3-CaS isothermal section diagram is confirmed.

Delimiting Inclusive Design

DEFF Research Database (Denmark)

Herriott, Richard

2014-01-01

This paper was written as an answer to the question raised by my PhD dissertation on accessibility through user-centred and Inclusive Design (ID) methods: can Inclusive Design be delimited? The literature on Inclusive Design deals almost entrirely with consumer product design and assistive...

Southern Federal University as a Center for the Development of Inclusive Education in the Region

Directory of Open Access Journals (Sweden)

Goryunova L.V.,

2017-08-01

Full Text Available The article provides an overview of best practices for inclusive education in higher educational institutions of the country, in terms of assessing its role in the development of inclusion in the regions. Cluster approach is proposed as the main approach to the development of regional inclusive education. The article describes the experience of organizing inclusive education in the Southern Federal University as a basic educational institution of higher education and as a cluster- forming educational organization that provides learning environment for persons with disabilities at all levels of education. The article also reveals the purpose and objectives of the university in the organization and implementation of quality inclusive education as a key development strategy. We analyze the actual state of inclusive education system at the university, which allows us to identify and describe the main activities of the Southern Federal University that ensure the establishment and development of inclusive education system both within the university and in the Rostov region in general. This also provides the opportunity to describe the current experience that may be incorporated in other institutions of higher education thus ensuring the effectiveness of formation of inclusive education system.

Preparation, characterization and in vitro evaluation of a new nucleotide analogue prodrug cyclodextrin inclusion complexes.

Science.gov (United States)

Diab, Roudayna; Jordheim, Lars P; Degobert, Ghania; Peyrottes, Suzanne; Périgaud, Christian; Dumontet, Charles; Fessi, Hatem

2009-01-01

Bis(tbutyl-S-acyl-2-thioethyl)-cytidine monophosophate is a new cytotoxic mononucleotide prodrug which have been developed to reverse the cellular resistance to nucleoside analogues. Unfortunately, its in vivo utilisation was hampered by its poor water solubility, raising the need of a molecular vector capable to mask its physicochemical characteristics although without affecting its cytotoxic activity. Hydroxypropyl-beta-cyclodextrin was used to prepare the prodrug inclusion complexes, allowing it to be solubilized in water and hence to be used for in vitro and in vivo experiments. A molar ratio of the cyclodextrin: prodrug of 3 was sufficient to obtain complete solubilization of the prodrug. The inclusion complex was characterized by differential scanning calorimetry, which revealed the disappearance of the melting peak of the prodrug suggesting the formation of inclusion complex. Proton Nuclear Magnetic Resonance spectroscopy provided a definitive proof of the inclusion complex formation, which was evidenced by the large chemical shift displacements observed for protons located in the interior of the hydrophobic cyclodextrin cavity. The complex retained its cytotoxic activity as shown by in vitro cell survival assays on murine leukemia cells. These results provided a basis for potential therapeutic applications of co-formulation of this new nucleotide analogue with hydroxypropyl-beta-CD in cancer therapy.

Social imaginaries and inclusion

DEFF Research Database (Denmark)

Hansen, Janne Hedegaard

2016-01-01

that inclusion on the one hand may be seen to be about human rights, solidarity, and democracy, and on the other hand, it is about ensuring the cohesion of neoliberal society by means of every person’s obligation to realize one’s potential through learning, development, and education regardless of one’s needs......, the development of inclusive schools and inclusive learning environments will involve both inclusion and exclusion processes. With this starting point, international educational research knowledge about inclusive schools and inclusive learning environments in general will be related to the fundamental dilemma...

SYNTHESIS AND EVALUATION OF β-CYCLODEXTRIN-EPICHLOROHYDRIN INCLUSION COMPLEX AS A PHARMACEUTICAL EXCIPIENT

Directory of Open Access Journals (Sweden)

K. N. Poornima

2015-05-01

Full Text Available A water soluble Beta-cyclodextrin-epichlorohydrin complex (Beta-CDEPI was synthesized by one-step condensation polymerization. Drug- Beta-CDEPI inclusion complexes were prepared and characterized. Inclusion complexes prepared using lyophilization technique was used to formulate orodispersible tablets. Compatibility studies showed no interaction and characterization proved substantial inclusion complex formation. Drug content was found between 97-99%. In-vitro disintegration time was found to be less than 3 minutes and all the formulations showed complete drug release of 100% within 15 minutes. The formulations were found to be stable for a period of 6 months. Beta-CDEPI polymer enhances the solubility and thus effectively can be utilized to improve the aqueous solubility of poorly water soluble drugs.

β-cyclodextrin inclusion complexes containing Citrus sinensis (L.) Osbeck essential oil: An alternative to control Aedes aegypti larvae

Energy Technology Data Exchange (ETDEWEB)

Galvão, J.G., E-mail: julianaggalvao@gmail.com [Pharmacy Department, Federal University of Sergipe, 49100-000 São Cristóvão, SE (Brazil); Silva, V.F.; Ferreira, S.G. [Pharmacy Department, Federal University of Sergipe, 49100-000 São Cristóvão, SE (Brazil); França, F.R.M. [Chemical Engineering Department, Federal University of Sergipe, 49100-000 São Cristóvão, SE (Brazil); Santos, D.A.; Freitas, L.S.; Alves, P.B. [Chemistry Department, Federal University of Sergipe, 49100-000 São Cristóvão, SE (Brazil); Araújo, A.A.S.; Cavalcanti, S.C.H.; Nunes, R.S. [Pharmacy Department, Federal University of Sergipe, 49100-000 São Cristóvão, SE (Brazil)

2015-05-20

Highlights: • Thermal analysis was useful to determine the formation of inclusion complexes by paste and co-precipitation methods. • HS/GC-FID quantitative analysis revealed that the best method of obtaining a CSEO/β-CD complex was the PWE, with the largest inclusion content [78.5%]. • The inclusion complex revealed LC{sub 50} of 23.01 ppm, close to CSEO LC{sub 50} 21.5 ppm. - Abstract: The development of β-cyclodextrin (β-CD) complexes is an interesting way for increasing the aqueous solubility of essential oils. The aim of this study was to prepare inclusion complexes of Citrus sinensis essential oil (CSEO) with β-CD using paste complexation (with and without co-solvent) and co-precipitation methods. Additionally, the physicochemical properties of the inclusion complexes using thermal analysis, X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy were evaluated. Furthermore, CSEO content (%) and solubility of complexes were measured. The biological activity against the Aedes aegypti Linn. larvae was further evaluated. For comparison purposes, a physical mixture between β-CD and CSEO was prepared and evaluated. Thermal analysis clearly indicated the formation of complexes by paste and co-precipitation methods. The headspace/gas chromatography quantitative analysis showed inclusions contents higher than 50%. On the other hand, the product revealed LC{sub 50} of 23.01 ppm, close to CSEO LC{sub 50} 21.5 ppm.

β-cyclodextrin inclusion complexes containing Citrus sinensis (L.) Osbeck essential oil: An alternative to control Aedes aegypti larvae

International Nuclear Information System (INIS)

Galvão, J.G.; Silva, V.F.; Ferreira, S.G.; França, F.R.M.; Santos, D.A.; Freitas, L.S.; Alves, P.B.; Araújo, A.A.S.; Cavalcanti, S.C.H.; Nunes, R.S.

2015-01-01

Highlights: • Thermal analysis was useful to determine the formation of inclusion complexes by paste and co-precipitation methods. • HS/GC-FID quantitative analysis revealed that the best method of obtaining a CSEO/β-CD complex was the PWE, with the largest inclusion content [78.5%]. • The inclusion complex revealed LC 50 of 23.01 ppm, close to CSEO LC 50 21.5 ppm. - Abstract: The development of β-cyclodextrin (β-CD) complexes is an interesting way for increasing the aqueous solubility of essential oils. The aim of this study was to prepare inclusion complexes of Citrus sinensis essential oil (CSEO) with β-CD using paste complexation (with and without co-solvent) and co-precipitation methods. Additionally, the physicochemical properties of the inclusion complexes using thermal analysis, X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy were evaluated. Furthermore, CSEO content (%) and solubility of complexes were measured. The biological activity against the Aedes aegypti Linn. larvae was further evaluated. For comparison purposes, a physical mixture between β-CD and CSEO was prepared and evaluated. Thermal analysis clearly indicated the formation of complexes by paste and co-precipitation methods. The headspace/gas chromatography quantitative analysis showed inclusions contents higher than 50%. On the other hand, the product revealed LC 50 of 23.01 ppm, close to CSEO LC 50 21.5 ppm

Phenotypic variability within the inclusion body spectrum of basophilic inclusion body disease and neuronal intermediate filament inclusion disease in frontotemporal lobar degenerations with FUS-positive inclusions.

Science.gov (United States)

Gelpi, Ellen; Lladó, Albert; Clarimón, Jordi; Rey, Maria Jesús; Rivera, Rosa Maria; Ezquerra, Mario; Antonell, Anna; Navarro-Otano, Judith; Ribalta, Teresa; Piñol-Ripoll, Gerard; Pérez, Anna; Valldeoriola, Francesc; Ferrer, Isidre

2012-09-01

Basophilic inclusion body disease and neuronal intermediate filament inclusion disease (NIFID) are rare diseases included among frontotemporal lobar degenerations with FUS-positive inclusions (FTLD-FUS). We report clinical and pathologic features of 2 new patients and reevaluate neuropathologic characteristics of 2 previously described cases, including an early-onset case of basophilic inclusion body disease (aged 38 years) with a 5-year disease course and abundant FUS-positive inclusion bodies and 3 NIFID cases. One NIFID case (aged 37 years) presented with early-onset psychiatric disturbances and rapidly progressive cognitive decline. Two NIFID cases had later onset (aged 64 years and 70 years) and complex neurologic deficits. Postmortem neuropathologic studies in late-onset NIFID cases disclosed α-internexin-positive "hyaline conglomerate"-type inclusions that were positive with 1 commercial anti-FUS antibody directed to residues 200 and 250, but these were negative to amino acids 90 and 220 of human FUS. Early-onset NIFID had similar inclusions that were positive with both commercial anti-FUS antibodies. Genetic testing performed on all cases revealed no FUS gene mutations. These findings indicate that phenotypic variability in NIFID, including clinical manifestations and particular neuropathologic findings, may be related to the age at onset and individual differences in the evolution of lesions.

Carbon dioxide fixation by Calvin-Cycle enzymes improves ethanol yield in yeast

NARCIS (Netherlands)

Guadalupe-Medina, V.; Wisselink, H.W.; Luttik, M.A.H.; De Hulster, E.; Daran, J.M.; Pronk, J.T.; Van Maris, A.J.A.

2013-01-01

Background Redox-cofactor balancing constrains product yields in anaerobic fermentation processes. This challenge is exemplified by the formation of glycerol as major by-product in yeast-based bioethanol production, which is a direct consequence of the need to reoxidize excess NADH and causes a loss

Use of hydroxypropyl-beta-cyclodextrin ad polymer matrix for formation of inclusion complex with drug nifedipine

International Nuclear Information System (INIS)

Carneiro, Elisa F.; Araujo, Marcia V.G. de; Barbosa, Ronilson V.; Silva, Caroline W.P. da; Barisson, Andersson; Zawadzki, Sonia F.; Andrade, George Ricardo S.; Costa Junior, Nivan B. da

2009-01-01

In this work it was prepared and characterized an inclusion complex between the polymeric matrix hydroxypropyl-beta cyclodextrin and nifedipine, a hydrophobic drug calcium antagonistic, used for the cardiovascular diseases treatment. The study of the phase- solubility diagram showed an increase of the aqueous solubility of the drug after inclusion, was observed and The differential scanning calorimetry analysis did not show the melting point temperature of the drug in the formed complex. This fact is considered as an evidence of the encapsulation process. 1 H NMR studies suggested that the non-aromatic ring of the nifedipine would be inserted in the cavity of the hydroxypropyl-beta-cyclodextrin.This orientation was also proposed by the used molecular modelling methods. (author)

A new occurrence of ambient inclusion trails from the ~1900-million-year-old Gunflint Formation, Ontario: nanocharacterization and testing of potential formation mechanisms.

Science.gov (United States)

Wacey, D; Saunders, M; Kong, C; Kilburn, M R

2016-09-01

Ambient inclusion trails (AITs) are tubular microstructures thought to form when a microscopic mineral crystal is propelled through a fine-grained rock matrix. Here, we report a new occurrence of AITs from a fossilized microbial mat within the 1878-Ma Gunflint Formation, at Current River, Ontario. The AITs are 1-15 μm in diameter, have pyrite as the propelled crystal, are infilled with chlorite and have been propelled through a microquartz (chert) or chlorite matrix. AITs most commonly originate at the boundary between pyrite- and chlorite-rich laminae and chert-filled fenestrae, with pyrite crystals propelled into the fenestrae. A subset of AITs originate within the fenestrae, rooted either within the chert or within patches of chlorite. Sulphur isotope data ((34) S/(32) S) obtained in situ from AIT pyrite have a δ(34) S of -8.5 to +8.0 ‰, indicating a maximum of ~30 ‰ fractionation from Palaeoproterozoic seawater sulphate (δ(34) S ≈ +20 ‰). Organic carbon is common both at the outer margins of the fenestrae and in patches of chlorite where most AITs originate, and can be found in smaller quantities further along some AITs towards the terminal pyrite grain. We infer that pyrite crystals now found within the AITs formed via the action of heterotrophic sulphate-reducing bacteria during early diagenesis within the microbial mat, as pore waters were becoming depleted in seawater sulphate. Gases derived from this process such as CO2 and H2 S were partially trapped within the microbial mat, helping produce birds-eye fenestrae, while rapid microquartz precipitation closed porosity. We propose that propulsion of the pyrite crystals to form AITs was driven by two complementary mechanisms during burial and low-grade metamorphism: firstly, thermal decomposition of residual organic material providing CO2 , and potentially CH4 , as propulsive gases, plus organic acids to locally dissolve the microquartz matrix; and secondly, reactions involving clay minerals that

Can Mn–S redox cycling drive sedimentary dolomite formation? A hypothesis

Energy Technology Data Exchange (ETDEWEB)

Petrash, Daniel A.; Lalonde, Stefan V.; González-Arismendi, Gabriela; Gordon, Robert A.; Méndez, José A.; Gingras, Murray K.; Konhauser, Kurt O. (CLS); (UCV-Venezuela); (CNRS-UMR); (Alberta)

2016-06-10

The formation of dolomite in modern peritidal environments is linked to the degradation of buried microbial mats, with complexation of Ca and Mg by extracellular polymeric substances (EPSs) and alkalinity generation through organic carbon respiration facilitating the nucleation of dolomite precursors. In the past two decades, microbial sulfate reduction, methanogenesis, and methanotrophy have all been considered as potential drivers of the nucleation process, but it remains unclear why dolomite formation could not also occur in suboxic sediments where abundant alkalinity is produced by processes linked to Mn(IV) and/or Fe(III) reduction coupled with the diffusion and reoxidation of reduced sulfur species. Here we report the interstitial occurrence of spheroidal aggregates of nanometer-scale Ca-rich dolomite rhombohedra within suboxic sediments associated with remnant microbial mats that developed in the peritidal zone of the Archipelago Los Roques, Venezuela. Multiple analytical tools, including EPMA, ICP-MS, synchrotron-based XRF and XRD, and spatially resolved XANES microanalyses, show that the dolomite-cemented interval exhibits depleted bulk iron concentrations, but is interstitially enriched in Mn and elemental sulfur (S⁰). Manganese occurs in several oxidation states, indicating that the dolomite-cemented interval was the locus of complex biological redox transformations characterized by coupled Mn and S cycling. The tight correspondence between sedimentary Mn and MgCO₃ concentrations further hints at a direct role for Mn during dolomitization. While additional studies are required to confirm its relevance in natural settings, we propose a model by which coupled Mn–S redox cycling may promote alkalinity generation and thus dolomite formation in manner similar to, or even more efficiently, than bacterial sulfate reduction alone.

Mechanisms of submicron inclusion re-equilibration during host mineral deformation

Science.gov (United States)

Griffiths, Thomas; Habler, Gerlinde; Abart, Rainer; Rhede, Dieter; Wirth, Richard

2014-05-01

data, and no subgrain boundaries. Secondly, garnet lattice rotation of up to 10° around rational garnet crystal axes is observed in connection with some already coarsened inclusions. Strain concentrations are widespread in some trails, but rare in others. A TEM foil transecting a garnet domain with concentrated lattice rotation in association with inclusions reveals well developed polygonal subgrain walls with few free dislocations. Where dislocation density is greatest, almost no <100nm inclusions are observed, whereas these are more abundant in unstrained garnet domains despite the foil being located entirely within the optically visible bleaching zone. Chlorite inclusions and formation of etch pits at dislocations at the garnet-chlorite interface demonstrate the presence of fluid along subgrain boundaries during this second bleaching process. In summary, brittle deformation in these garnets led to enhanced transport and inclusion re-equilibration by coarsening, forming inclusion trails. The precise mechanism allowing enhanced transport is still to be determined and may have involved fluid supply with or without pipe diffusion along introduced dislocations. Later ductile deformation via dislocations, concentrated at already coarsened inclusions and enhanced by fluid availability, further affected the nanoinclusion population. The inclusion trail microstructure records complex small-scale interaction between deformation and reaction, shedding light on the mechanisms by which re-equilibration and strain localisation can influence each other in deforming host-inclusion systems. Bestmann et al. (2008) Journal of Structural Geology 30: 777-790

Inclusion complex of tamibarotene with hydroxypropyl-β-cyclodextrin: Preparation, characterization, in-vitro and in-vivo evaluation

Directory of Open Access Journals (Sweden)

Ying Yang

2017-03-01

Full Text Available The goal of this study was to improve the solubility and oral bioavailability of tamibarotene by complexing it with hydroxypropyl-β-cyclodextrin (HP-β-CD. The inclusion complex of tamibarotene with hydroxypropyl-β-cyclodextrin (Am80-HP-β-CD was prepared through a freeze-drying method at the mole ratio of 1:1 (Am80: HP-β-CD. Fourier transform infrared spectroscopy (FT-IR and differential scanning calorimetry (DSC indicated the formation of Am80-HP-β-CD. In vitro dissolution studies showed that the solubility and dissolution percentage of Am80-HP-β-CD was improved substantially compared to Am80. An improved dissolution with approximately 97% drug release in 3 min was observed, in comparison with Am80 with approximately 60% release in 45 min. In vivo studies indicated that the AUC0-∞ has increased 2.79 times and the Cmax 4.37 times after the formation of inclusion complex. The decrease of tmax indicated the Am80-HP-β-CD inclusion complex can be absorbed into blood faster. In short, the solubility and bio-availability of Am80 has notably increased with the complexation of HP-β-CD. Therefore, using the inclusion technique is a promising method to improve the solubility of insoluble drugs.

The non-destructive analysis of fluid inclusions in minerals using the proton microprobe

Energy Technology Data Exchange (ETDEWEB)

Ryan, C.G.; Van Achterbergy, E. [Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW (Australia). Div. of Exploration Geoscience; Heinrich, C.A. [ETH Zentrum, Zurich, (Switzerland). Department Erdwissenschaften; Mernagh, T.P. [Max-Planck-Institut fuer Chemie (Otto-Hahn-Institut), Mainz (Germany); Zaw, K. [Tasmania Univ., Sandy Bay, TAS (Australia)

1996-12-31

The study of ore forming fluids trapped as fluid inclusions in minerals is the key to understanding fluid flow paths at the time of ore formation and to predicting the location of ore bodies within large-scale magmatic hydrothermal systems. The large penetration depths and the predictable nature of MeV proton trajectories and X-ray absorption enables reliable modelling of PIXE yields and the development of standardless quantitative analytical methods. This permits quantitative microanalysis of minerals at ppm levels, and more recently has enabled the development of methods for quantitative trace-element imaging and the quantitative, non-destructive analysis of individual fluid inclusions. This paper reports on recent developments in Proton Microprobe techniques with special emphasis on ore systems and fluid inclusion analysis. 6 refs., 2 figs.

The non-destructive analysis of fluid inclusions in minerals using the proton microprobe

Energy Technology Data Exchange (ETDEWEB)

Ryan, C G; Van Achterbergy, E [Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW (Australia). Div. of Exploration Geoscience; Heinrich, C A [ETH Zentrum, Zurich, (Switzerland). Department Erdwissenschaften; Mernagh, T P [Max-Planck-Institut fuer Chemie (Otto-Hahn-Institut), Mainz (Germany); Zaw, K [Tasmania Univ., Sandy Bay, TAS (Australia)

1997-12-31

The study of ore forming fluids trapped as fluid inclusions in minerals is the key to understanding fluid flow paths at the time of ore formation and to predicting the location of ore bodies within large-scale magmatic hydrothermal systems. The large penetration depths and the predictable nature of MeV proton trajectories and X-ray absorption enables reliable modelling of PIXE yields and the development of standardless quantitative analytical methods. This permits quantitative microanalysis of minerals at ppm levels, and more recently has enabled the development of methods for quantitative trace-element imaging and the quantitative, non-destructive analysis of individual fluid inclusions. This paper reports on recent developments in Proton Microprobe techniques with special emphasis on ore systems and fluid inclusion analysis. 6 refs., 2 figs.

Building inclusive engineering identities: implications for changing engineering culture

Science.gov (United States)

Atadero, Rebecca A.; Paguyo, Christina H.; Rambo-Hernandez, Karen E.; Henderson, Heather L.

2018-05-01

Ongoing efforts to broaden the participation of women and people of colour in engineering degree programmes and careers have had limited success. This paper describes a different approach to broadening participation that seeks to work with all students and develop inclusive engineering identities. Researchers worked with the instructors of two first-year engineering courses to integrate curriculum activities designed to promote the formation of engineering identities and build an appreciation for how diversity and inclusion strengthen engineering practice. Multilevel modelling results indicated positive effects of the intervention on appreciation for diversity but no effects on engineering identity, and qualitative results indicated students learned the most about diversity not through one of the intervention activities, but through team projects in the courses. We also describe lessons learned in how to teach engineering students about diversity in ways that are relevant to engineering.

Modification of Alumina and Spinel Inclusions by Calcium in Liquid Steel

Science.gov (United States)

Verma, Neerav

2011-12-01

samples were characterized for inclusion shape, size and chemistry through scanning electron microscopy (SEM). Automated inclusion analysis tools (like ASCAT [59, 91, 92], INCA-GSR [126]; Please refer section 6.4., page number 68) were employed to generate statistical information of the inclusions. Thermodynamic database software FACTSAGE [62] was used to determine thermochemistry of reactions, ternary phase diagrams (Ca-Al-S and Ca-Al-Mg systems). The compositions of the inclusions were tracked before and after calcium treatment to determine the effectiveness of calcium treatment. Extraction of inclusions through dissolution of iron in bromine-methanol solution was employed to reveal 3-D geometry of inclusions and analyze inclusions through EDS (Energy-dispersive X-ray spectroscopy) without any matrix effects. Various industrial samples were also analyzed to confirm the feasibility of various reaction mechanisms deduced through experiments. Successful modification of alumina and spinel inclusions by calcium was demonstrated [85, 86]. It was observed that these modification mechanisms proceed through transient phase (CaO, CaS) formation. In the case of spinels, preferential reduction of MgO part was also observed during calcium modification of spinels. The magnesium after MgO reduction by calcium can enter back into the melt or leave the melt in vapor form. The inclusion area fraction decreased after calcium treatment, but the inclusion concentration (number of inclusions per cm2) increased because inclusions shifted to a smaller size distribution after calcium treatment. Severe matrix effects during EDS analysis of inclusions were observed, due to which inclusion composition analyses can be significantly affected. *Please refer to dissertation for footnotes.

Application of preparative disk gel electrophoresis for antigen purification from inclusion bodies.

Science.gov (United States)

Okegawa, Yuki; Koshino, Masanori; Okushima, Teruya; Motohashi, Ken

2016-02-01

Specific antibodies are a reliable tool to examine protein expression patterns and to determine the protein localizations within cells. Generally, recombinant proteins are used as antigens for specific antibody production. However, recombinant proteins from mammals and plants are often overexpressed as insoluble inclusion bodies in Escherichia coli. Solubilization of these inclusion bodies is desirable because soluble antigens are more suitable for injection into animals to be immunized. Furthermore, highly purified proteins are also required for specific antibody production. Plastidic acetyl-CoA carboxylase (ACCase: EC 6.4.1.2) from Arabidopsis thaliana, which catalyzes the formation of malonyl-CoA from acetyl-CoA in chloroplasts, formed inclusion bodies when the recombinant protein was overexpressed in E. coli. To obtain the purified protein to use as an antigen, we applied preparative disk gel electrophoresis for protein purification from inclusion bodies. This method is suitable for antigen preparation from inclusion bodies because the purified protein is recovered as a soluble fraction in electrode running buffer containing 0.1% sodium dodecyl sulfate that can be directly injected into immune animals, and it can be used for large-scale antigen preparation (several tens of milligrams). Copyright © 2015 Elsevier Inc. All rights reserved.

Final Technical Report. Factors Controlling In Situ Uranium and Technetium Bio-Reduction and Reoxidation at the NABIR Field Research Center

International Nuclear Information System (INIS)

Dr. Jonathan D. Istok , Oregon State University; Dr. Lee Krumholz, University of Oklahoma; Dr. James McKinley, Pacific Northwest National Laboratory; Dr. Baohua Gu, Oak Ridge National Laboratory

2006-01-01

The overall goal of this project was to better understand factors and processes controlling microbially-mediated reduction and reoxidation of U and Tc in the unconsolidated residuum overlying the Nolichucky shale at the Field Research Center (FRC) at Oak Ridge National Laboratory. Project activities were designed to test the following hypotheses: (1) The small rates of denitrification and U bio-reduction observed in laboratory incubations of sediments from FRC Area 1 at low pH (< 5) are due to the presence of high concentrations of toxic metals (especially Al and Ni). Rates of Tc reduction will also be small at low pH in the presence of high concentrations of toxic metals. (2) In situ rates of U and perhaps Tc bio-reduction can be increased by increasing system pH and thus precipitating toxic metals from solution. (3) In situ rates of U and Tc bio-reduction can be increased by the addition of humic substances, which complex toxic metals such as Al and Ni, buffer pH, and serve as electron shuttles to facilitate U and Tc reduction. (4) Microbially-reduced U and Tc are rapidly oxidized in the presence of high concentrations of NO3- and the denitrification intermediates NO2-, N2O, and NO. (5) An electron-donor-addition strategy (type and form of donor, with or without pH adjustment and with or without the co-addition of humic substances) can be devised to reduce U and Tc concentrations for an extended period of time in low pH groundwater in the presence of high concentrations of NO3-, Al, and Ni. This strategy operates by removing or complexing these components of FRC groundwater to allow the subsequent reduction of U(VI) and Tc(VII)

Inclusive and semi-inclusive analysis from polarised deep-inelastic muon scattering

International Nuclear Information System (INIS)

Kageya, T.

1999-01-01

We present new results for the spin-dependent structure function on the proton and for the polarised quark distributions in the nucleon from semi-inclusive spin asymmetries. With the inclusive asymmetry from deep inelastic scattering of polarised muons on polarised protons, it is found that the Ellis-Jaffe sum rule is violated. Using our results for Γ d 1 , the Bjorken sum rule is confirmed with an accuracy of about 15%. From semi-inclusive spin asymmetries and SMC inclusive spin asymmetries, we determine the polarised quark distributions of valence u and d quarks to be positive and negative, respectively, while the non-strange sea distribution to be consistent with zero

Inclusive pedagogy

DEFF Research Database (Denmark)

Korsgaard, Morten Timmermann; Skov Mortensen, Stig

This article will present a case for a shift in perspective in inclusive education research towards a continentally inspired approach. Drawing on the age old distinction between continental and Anglo-American educational research the aim is to flesh out what a shift to a continental approach...... will entail, and why it might be beneficial to research in inclusive education...

Stable isotope signatures of gases liberated from fluid inclusions in bedrock at Olkiluoto

International Nuclear Information System (INIS)

Eichinger, F.; Meier, D.; Haemmerli, J.; Diamond, L.

2010-12-01

Fluid inclusions in quartzes of the Olkiluoto bedrock contain gaseous N 2 , CO 2 , H 2 , CH 4 , and higher hydrocarbons in varying proportions. Stable carbon and hydrogen isotope signatures of the gas phases give valuable information on their origin and the formation conditions. In previous studies, a method to liberate and quantify the gases trapped in fluid inclusions was developed. It allowed determining the carbon isotope signatures of liberated CO 2 , CH 4 and higher hydrocarbons (HHC), but no hydrogen isotope data were acquired. The method was advanced and, in this study, also stable hydrogen isotopes of CH 4 and H 2 liberated from fluid inclusions could be analysed. The stable carbon signatures of methane and higher hydrocarbons, as well as the hydrogen isotope signatures of methane indicate a predominant thermogenic provenance for those gases. (orig.)

Inclusive characteristics of the nuclear target fragmentation products induced by relativistic particles

International Nuclear Information System (INIS)

Bogatin, V.I.; Ganza, E.A.; Lozhkin, O.V.; Murin, Yu.A.; Oplavin, V.S.; Perfilov, N.A.; Yakovlev, Yu.P.

1981-01-01

An experimental investigation of inclusive characteristics of nuclei-target fragmentation is conducted for further development and test of physical value of the earlier suggested nuclear fragmentation model based on the connection of the fragmentation with fluctuations of the quasiparticle density in the two-component quantum liquid, an experimental investigation of the inclusive characteristics of the nuclei-target fragmentation is carried out. The processes of sup(3, 4, 6, 8)He and sup(6, 7, 8, 9, 11)Li fragment formation during the interaction of relativistic protons (Esub(p)=6.7 GeV) and deutrons (Esub(d)=3.1 GeV) with 112 Sn and 124 Sn isotopes are studied by the method of semiconductive ΔE-E detectors. Differential energy spectra of fragments and isotopic ratio of cross sections of their formation as well as data on the dependence of isotopic ratios of fragmentation cross sections on the energy of incident particles and on the fragment energy are obtained. Presented is a phenomenological model of fragmentation within the frames of which the obtained experimental data are analyzed [ru

Teacher’s needed knowledge to promote the inclusion of students with Educational Special needs

Directory of Open Access Journals (Sweden)

Gislaine Semcovici Nozi

2012-08-01

Full Text Available The main objective of the following paper is to identify, by a revision from the specialized area literature, the needed knowledge required by teachers to promote the inclusion of students with special educational needs (SEN in regular education. To achieve this goal, was prepared a bibliographic survey from seven magazines, ten books’ chapters and three dissertations from Education and special education area, produced between 2005 and 2009. The achieved data was organized into categories. The results indicate the necessity of specific theoretical, conceptual and methodological knowledge to include students in an ordinary classroom. Between all knowledge indicated by the checked authors, is pointed out the understanding related to corporative and collaborative method and technique to favor the inclusion of students with SEN; the characteristics of these students, to the procedure didactic-pedagogic to favor the inclusion; to the legislation and fundamentals from inclusive education; to the social barriers that difficult the inclusion process from students with SEN, among others. We consider that this research result can contribute to subsidize the content organization which will be contemplated in the teaching training and continued formation process and/or teachers who are working to favor the inclusion process for SEN students.

Inclusion: Conceptualization and measurement

NARCIS (Netherlands)

Jansen, W.S.; Otten, S.; Van der Zee, K.I.; Jans, L.

2014-01-01

n the present research, we introduced a conceptual framework of inclusion and subsequently used this as a starting point to develop and validate a scale to measure perceptions of inclusion. Departing from existing work on inclusion and complementing this with theoretical insights from optimal

Inclusion : Conceptualization and measurement

NARCIS (Netherlands)

Jansen, Wiebren S.; Otten, Sabine; van der Zee, Karen I.; Jans, Lise

In the present research, we introduced a conceptual framework of inclusion and subsequently used this as a starting point to develop and validate a scale to measure perceptions of inclusion. Departing from existing work on inclusion and complementing this with theoretical insights from optimal

Inclusion: Conceptualization and measurement

NARCIS (Netherlands)

Jansens, Wiebren S.; Otten, Sabine; van der Zee, Karen; Jans, Lise

2014-01-01

In the present research, we introduced a conceptual framework of inclusion and subsequently used this as a starting point to develop and validate a scale to measure perceptions of inclusion. Departing from existing work on inclusion and complementing this with theoretical insights from optimal

Explosive Breakup of a Water Droplet with a Nontransparent Solid Inclusion Heated in a High-Temperature Gaseous Medium

Directory of Open Access Journals (Sweden)

Dmitrienko Margarita A.

2015-01-01

Full Text Available This paper investigates the evaporation of a water droplet with a comparably sized solid nontransparent inclusion in a high-temperature (500–800 K gas medium. Water evaporates from the free surface of the inclusion. During this process, intensive vapor formation occurs on the inner interface “water droplet – solid inclusion” with the subsequent explosive decay of the droplet. Experiments have been conducted using high-speed (up to 105 fps video cameras “Phantom” and software “Phantom Camera Control”. The conditions of the explosive vapor formation of the heterogeneous water droplet were found. The typical phase change mechanisms of the heterogeneous water droplet under the conditions of intensive heat exchange were determined.

The behavior of mineral inclusions during host decomposition. A SEM-STEM study of rutile inclusions at a natural propagating corundum-spinel interface.

Science.gov (United States)

Baldwin, Lisa; Li, Chen; Habler, Gerlinde; Abart, Rainer

2017-04-01

When two neighbor phases are not in chemical equilibrium, they may react and produce a reaction rim at their interface, separating the mutually incompatible phases. At constant P-T-X conditions, such a reaction will continue until one of the reactants is completely consumed. Reaction rim growth involves transfer of chemical components across the growing rim by long-range diffusion and localized interface reactions on either side of the growing rim. Consequently, the thickness of the reaction rim will be a function of time. Yet, in order to quantify and interpret such corona structures and to define a reaction rate law, the kinetics and mechanism of rim formation must be well constrained. In particular, the coupling between long-range diffusion, and interface reaction must be known. In this contribution we focus on potential complexities associated with interface reactions. Many natural minerals contain inclusions of other phases, which in turn may influence the reaction interface propagation kinetics during host phase decomposition (Ashby et al. 1969), as a propagating reaction interface dissipates more free energy when bypassing a mineral inclusion, resulting in a locally decelerated reaction rate. Here, we report results of a SEM-STEM study of the interface between natural rutile-bearing corundum and a polycrystalline ferromagnesio-aluminate spinel that grew topotactically with respect to the corundum precursor as a consequence of its reaction with FeO and MgO from basaltic melt. Electron Backscatter Diffraction (EBSD) crystal orientation imaging revealed that the spinel rim is polycrystalline and exhibits (111) twinning that is parallel to the corundum (0001) plane. The rutile inclusions in corundum are elongated perpendicular to the corundum [0001] axis and are randomly oriented in the (0001) plane. Furthermore, they follow an oscillatory grain size distribution zonation with grain sizes being either a few tens of nanometers, or about 500 to 800 nanometers in

Evidence on Inclusion

DEFF Research Database (Denmark)

Dyssegaard, Camilla Brørup; Larsen, Michael Søgaard

The purpose of this publication is to examine existing research on inclusion to identify strategies of inclusion that have generated positive effects. To do so it is necessary to understand the effect of the applied strategies. One approach, which is being discussed, is to use evidence to determine...... which methods have proven more effective than others. The desire to gain insight into research on inclusion forms the basis of the current systematic review. The task was to determine which strategies primary research has found to be most effective for inclusion purposes. We have solved this task...... by addressing the existing research with the following question: What is the effect of including children with special needs in mainstream teaching in basic school, and which of the applied educational methods have proved to have a positive effect?...

Physical and chemical properties of fluid and melt inclusions of the Lagoa Real uraniferous albitites (Brazil)

International Nuclear Information System (INIS)

Chaves, Alexandre de Oliveira

2010-01-01

Data of melt and fluid inclusions obtained by LA-ICP-MS and microthermometry techniques represent an important investigation complement to understand geological processes which took place in Lagoa Real uraniferous albitites (Brazil). Melt inclusions found in augite structure, which reveals the previous presence of U in the syenitic magma. Primary fluid inclusions in magmatic augite of the albitites contain Na, denoting once more its presence in original magma. The formation of andradite from augite during shear events that generated the metamorphosed syenite (uraniferous albitite) was certified by the ICP-MS signals and uranium released by magmatic titanite (U source mineral)during the 1.9 Ga metamorphism was recorded in the fluid inclusions found in andradite, mineral that was formed in this same metamorphic event which recrystallized titanite crystals. Such uranium was responsible by precipitation of the disseminated uraninite found inside andradite. (author)

Catalytically-active inclusion bodies-Carrier-free protein immobilizates for application in biotechnology and biomedicine.

Science.gov (United States)

Krauss, Ulrich; Jäger, Vera D; Diener, Martin; Pohl, Martina; Jaeger, Karl-Erich

2017-09-20

Bacterial inclusion bodies (IBs) consist of unfolded protein aggregates and represent inactive waste products often accumulating during heterologous overexpression of recombinant genes in Escherichia coli. This general misconception has been challenged in recent years by the discovery that IBs, apart from misfolded polypeptides, can also contain substantial amounts of active and thus correctly or native-like folded protein. The corresponding catalytically-active inclusion bodies (CatIBs) can be regarded as a biologically-active sub-micrometer sized biomaterial or naturally-produced carrier-free protein immobilizate. Fusion of polypeptide (protein) tags can induce CatIB formation paving the way towards the wider application of CatIBs in synthetic chemistry, biocatalysis and biomedicine. In the present review we summarize the history of CatIBs, present the molecular-biological tools that are available to induce CatIB formation, and highlight potential lines of application. In the second part findings regarding the formation, architecture, and structure of (Cat)IBs are summarized. Finally, an overview is presented about the available bioinformatic tools that potentially allow for the prediction of aggregation and thus (Cat)IB formation. This review aims at demonstrating the potential of CatIBs for biotechnology and hopefully contributes to a wider acceptance of this promising, yet not widely utilized, protein preparation. Copyright © 2017 Elsevier B.V. All rights reserved.

Footstep towards Inclusive Education

Science.gov (United States)

Abbas, Faiza; Zafar, Aneeka; Naz, Tayyaba

2016-01-01

Inclusive education is a rising trend in the world. The first step towards inclusive education is providing the awareness to the general education teachers. This study focused to investigate the general education teachers of primary and secondary level awareness about the special education and inclusive education. This study is descriptive method…

More Policies, Greater Inclusion? Exploring the Contradictions of New Labour Inclusive Education Policy

Science.gov (United States)

Roulstone, Alan; Prideaux, Simon

2008-01-01

The era of New Labour government has witnessed unprecedented growth in inclusive education policies. There is, however, limited evidence that policies have increased disabled children's inclusion. This article explores reasons for this contradiction. Drawing on sociological insights, it is argued that New Labour policies on inclusive education…

Nuclear microscopy of fluid inclusions at the CSIRO

International Nuclear Information System (INIS)

Ryan, C.; Van Achterbergh, E.; Win, T.T.; McInnes, B.; Cripps, G.; Suter, G.; Liu, W.

2003-01-01

Full text: The deep penetration of a MeV energy proton beam and the predictable nature of X-ray production using proton induced X-ray emission (PIXE) make the nuclear microprobe ideally suited to the imaging and analysis of fluid and melt inclusions in minerals. MeV protons interact with a target through electronic interactions with a loss of ∼100 eV per collision. Such small energy loss leads to a smooth and predictable slowing down behaviour with a small energy uncertainty. Furthermore, the small momentum transfers in these collisions result in negligible spreading of the beam (e.g. ∼1 μm at 40 μm depth in quartz). Hence, the proton path can be regarded as linear. The principle mechanisms for proton energy loss, proton-induced ionization, secondary fluorescence and X-ray absorption and detection are understood and well characterized. This enables the integration of expected PIXE X-ray yields along the path of the proton beam and provides the foundation for a standardless microanalytical method. A strength of standardless PIXE analysis enables the approach to be extended to complex problems where the production of standards becomes impractical or unrepresentative of natural samples. One such problem is the study of ore metal transport and ore formation processes using the non-destructive analysis of fluids trapped as fluid inclusions in minerals using a raster-scanned proton probe. In this case, the integration of PIXE X-rays can be confined to the volume of the fluid inclusion in order to calculate the yield of elemental X-rays per ppm of an element. This calculation is illustrated, which shows one volume element of the fluid inclusion excited by the beam and the X-ray path to a detector. The CSIRO-GEMOC Nuclear Microprobe can focus a 3 MeV proton beam into a 1.3 μm beam spot for fluid inclusion analysis and intense beams for mineral imaging at 1.8 μm resolution (Ryan et al., 2001a). Quantitative elemental images are projected using the Dynamic Analysis

Linguistic Diversity and Social Inclusion

Science.gov (United States)

Piller, Ingrid; Takahashi, Kimie

2011-01-01

This introduction provides the framework for the special issue by describing the social inclusion agenda of neoliberal market democracies. While the social inclusion agenda has been widely adopted, social inclusion policies are often blind to the ways in which language proficiency and language ideologies mediate social inclusion in linguistically…

Inclusive pedagogy

DEFF Research Database (Denmark)

Korsgaard, Morten Timmermann; Mortensen, Stig Skov

of education. The article explores the relationship between Continental and Anglo-American educational theory, and why they seem to have developed in such distinct directions. Beginning with the Anglo-American perspective it is outlined how pedagogy and the so called educational interest became replaced...... and the politicisation of inclusive education, and a positive aim in the form of an argument for a move towards constructing a pedagogical ideal of inclusion....

X-ray topographic study of diamonds: implications for the genetic nature of inclusions in diamond

Science.gov (United States)

Agrosì, Giovanna; Nestola, Fabrizio; Tempesta, Gioacchino; Bruno, Marco; Scandale, Eugenio; Harris, Jeff W.

2014-05-01

In recent years, several studies have focused on the growth conditions of the diamonds through the analysis of the mineral inclusions trapped in them (Howell, 2012 and references therein). Nevertheless, to obtain rigorous information about chemical and physical conditions of diamond formation, it is crucial to determine if the crystallization of the inclusions occurred before (protogenetic nature), during (syngenetic nature) or after (epigenetic nature) the growth of diamond (Wiggers de Vries et al., 2011). X-ray topography (XRDT) can be a helpful tool to verify the genetic nature of inclusions in diamond. This technique characterizes the extended defects and reconstructs the growth history of the samples (Agrosì et al., 2013 and references therein) and, consequently contributes to elucidation of the relationship between the inclusions and the host-diamond. With this aim a diamond from the Udachnaya kimberlite, Siberia, was investigated. The diamond crystal was the one previously studied by Nestola et al. (2011) who performed in-situ crystal structure refinement of the inclusions to obtain data about the formation pressure. The inclusions were iso-oriented olivines that did not show evident cracks and subsequently could not be considered epigenetic. Optical observations revealed an anomalous birefringence in the adjacent diamond and the inclusions had typical "diamond-imposed cubo-octahedral" shape for the largest olivine. The diffraction contrast study shows that the diamond exhibits significant deformation fields related to plastic post growth deformation. The crystallographic direction of strains was established applying the extinction criterion. Section topographs were taken to minimize the overlapping of the strain field associate with the different defects and revealed that no dislocations nucleated from the olivine inclusions. Generally, when a solid inclusion has been incorporated in the growing crystal, the associated volume distortion can be minimized by

Inclusion in the East: Chinese Students' Attitudes towards Inclusive Education

Science.gov (United States)

Malinen, Olli-Pekka; Savolainen, Hannu

2008-01-01

A sample of 523 Chinese university students was given a questionnaire on their attitudes towards the inclusion of children with disabilities into regular classrooms. Factor analysis, analysis of variance, t-test and correlations were used to assess the respondents' general attitude towards inclusion, the factor structure of the attitudes, the…

Homogenisation of sulphide inclusions within diamonds: A new approach to diamond inclusion geochemistry

Science.gov (United States)

McDonald, Iain; Hughes, Hannah S. R.; Butler, Ian B.; Harris, Jeffrey W.; Muir, Duncan

2017-11-01

Base metal sulphide (BMS) inclusions in diamonds provide a unique insight into the chalcophile and highly siderophile element composition of the mantle. Entombed within their diamond hosts, these provide a more robust (closed system) sample, from which to determine the trace element, Re-Os and S-isotopic compositions of the mantle than mantle xenoliths or orogenic peridotites, as they are shielded from alteration during ascent to the Earth's crust and subsequent surface weathering. However, at temperatures below 1100 °C some BMS inclusions undergo subsolidus re-equilibration from an original monosulphide solid solution (Mss) and this causes fractionation of the major and trace elements within the inclusions. Thus to study the subjects noted above, current techniques require the entire BMS inclusion to be extracted for analyses. Unfortunately, 'flaking' of inclusions during break-out is a frequent occurrence and hence the risk of accidentally under-sampling a portion of the BMS inclusion is inherent in current practices. This loss may have significant implications for Re-Os isotope analyses where incomplete sampling of a Re-rich phase, such as chalcopyrite that typically occurs at the outer margins of BMS inclusions, may induce significant bias in the Re-Os and 187Os/188Os measurements and resulting model and isochron ages. We have developed a method for the homogenisation of BMS inclusions in diamond prior to their break-out from the host stone. Diamonds are heated to 1100 °C and then quenched to chemically homogenise any sulphide inclusions for both major and trace elements. Using X-ray Computed Microtomography (μCT) we determine the shape and spatial setting of multiple inclusions within a host stone and crucially show that the volume of a BMS inclusion is the same both before and after homogenisation. We show that the homogenisation process significantly reduces the inherent variability of in situ analysis when compared with unhomogenised BMS, thereby

Limitations of inclusive fitness.

Science.gov (United States)

Allen, Benjamin; Nowak, Martin A; Wilson, Edward O

2013-12-10

Until recently, inclusive fitness has been widely accepted as a general method to explain the evolution of social behavior. Affirming and expanding earlier criticism, we demonstrate that inclusive fitness is instead a limited concept, which exists only for a small subset of evolutionary processes. Inclusive fitness assumes that personal fitness is the sum of additive components caused by individual actions. This assumption does not hold for the majority of evolutionary processes or scenarios. To sidestep this limitation, inclusive fitness theorists have proposed a method using linear regression. On the basis of this method, it is claimed that inclusive fitness theory (i) predicts the direction of allele frequency changes, (ii) reveals the reasons for these changes, (iii) is as general as natural selection, and (iv) provides a universal design principle for evolution. In this paper we evaluate these claims, and show that all of them are unfounded. If the objective is to analyze whether mutations that modify social behavior are favored or opposed by natural selection, then no aspect of inclusive fitness theory is needed.

Determination of Three-Dimensional Morphology and Inner Structure of Second-Phase Inclusions in Metals by Non-Aqueous Solution Electrolytic and Room Temperature Organic Methods

Directory of Open Access Journals (Sweden)

Jing Guo

2018-01-01

Full Text Available The secondary-phase particles in metals, particularly those composed of non-metallic materials, are often detrimental to the mechanical properties of metals; thus, it is crucial to control inclusion formation and growth. One of the challenges is determining the three-dimensional morphology and inner structures of such inclusions. In this study, a non-aqueous solution electrolytic method and a room-temperature organic technique were developed based on the principle of electrochemistry to determine the three-dimensional morphologies and inner structures of non-metallic inclusions in Al-killed steel, Si-killed steel, and ductile cast iron. The inclusions were first extracted without any damage to the inclusions, and then the collected inclusions were wrapped and cut through Cu ion deposition. The results revealed that the inclusions in Al-killed steel had an irregular morphology, that those in the Si-killed steel were mainly spherical, and that almost all the spheroidal graphite in the ductile cast iron featured a uniform globular morphology. In addition, nucleation was not observed in the inner structures of the inclusions in the Al-killed steel, while some dendritic or rod-like MnS phase precipitates appeared on the silicate inclusion surfaces, and some silicate-rich phases were detected in their inner matrix. For spheroidal graphite, rare-earth oxides (one particle or more were observed as nuclei in the center of almost every graphite particle. The formation and evolution of inclusions in these types of metals can be better understood by means of the two developed methods.

Iodine K-edge EXAFS analysis of iodide ion-cyclodextrin inclusion complexes in aqueous solution

International Nuclear Information System (INIS)

Kaneko, T; Ueda, M; Nagamatsu, S; Konishi, T; Fujikawa, T; Mizumaki, M

2009-01-01

We study the structure of inclusion complexes of α-, β-, γ-cyclodextrin with mono-iodide ion in aqueous solution by means of iodine K-edge EXAFS spectroscopy. The analysis is based on the assumption that two kinds of iodide ions exist in KI-cyclodextrin aqueous solution i.e. hydrated mono-iodide ions and one-one mono-iodide-cyclodextrin inclusion complexes. In KI-α-cyclodextrin system, iodine K-edge EXAFS analyse show that the average coordination number of the oxygen atoms in water molecules in the first hydration shell decreases as the fraction of included ions increases. This result suggests that dehydration process accompanies the formation of the inclusion complex. This is not found in the case of β-cyclodextrin, indicating that in this case the iodide ions are included together with the whole first hydration shell.

Change of sulfide inclusions in steel microalloying with rare earth and alkaline-earth elements

International Nuclear Information System (INIS)

Averin, V.V.; Polonskaya, S.M.; Chistyakov, V.F.

1977-01-01

The conditions for the formation of sulfides in molten and solid iron were determined by considering the thermodynamics of the interaction of sulfur and of oxygen with various components. It was shown in casting of low-carbon steel under a blanket of slag-forming briquettes, calcium of the silicocalcium partly passes to iron and to the sulfide phase. The sulfide inclusions with calcium in rolling become lens-shaped and acquire a greater strength, proportional to the content of calcium, thus ensuring a lesser anisotropy of steel. The change in the shape and the composition of sulfide inclusions effects the fracture of the metal which changes in type from separation along lamellar inclusions to a plastic fracture, i.e., enhances resilience. It is thus noted that rare-earth and alkali-earth elements, in particular, cerium and calcium are promising agents for desulfurating molten iron

Study on the inclusion behavior of p-sulfonatocalix[6]arene with propranolol by spectrofluorometry

Science.gov (United States)

Li, Hui; Song, Jin-Ping; Chao, Jian-Bin; Shuang, Shao-Min; Dong, Chuan

2012-11-01

The inclusion interaction between propranolol (PPL) and p-sulfonatocalix[6]arene (SCX6) was investigated by fluorescence and 1H NMR spectroscopy. Influences of pH, temperature, ionic strength and the concentration of SCX6 were examined in detail. In phosphate buffer solution with pH 7.5, the fluorescence of PPL dramatically quenched upon addition of SCX6 revealing the formation of inclusion complexes between PPL and SCX6. The stoichiometric ratio was verified to be 1:1 by the continuous variation method. The inclusion constant of PPL-SCX6 complexes was calculated as 2.2 × 104 L/mol by the nonlinear curve fitting method. 1H NMR titration spectra testified that the aliphatic chain of PPL may be partially penetrated into the hydrophobic cavity of SCX6. This was confirmed by molecular dynamics calculations.

Inclusive innovation: a research project on the inclusion of social responsibility

NARCIS (Netherlands)

Nijhof, A.H.J.; Fisscher, O.A.M.; de Bakker, F.G.A.

2001-01-01

The research project 'Inclusive Innovation' aims at stimulating dialogue about inclusion of social responsibility based on universal human rights in the conduct of business. This dialogue concerns both the communication within the organisation and between the organisation and interested parties in

Inclusion study of hourglass amethyst from Boudi (Morocco) by Raman microspectroscopy and microthermometric measurements

Science.gov (United States)

Dumańska-Słowik, Magdalena; Toboła, Tomasz; Jarmołowicz-Szulc, Katarzyna; Naglik, Beata; Dyląg, Joanna; Szczerba, Jacek

2017-12-01

Amethyst from Boudi with characteristic hourglass colour zoning hosts numerous pseudo-secondary fluid and mineral inclusions. Measured values of temperature homogenization (Th) for selected fluid inclusion assemblages (FIA) in colourless and violet regions of the crystal range from 154 to 330 °C. The higher temperatures values are characteristic for violet zones than colourless regions of the crystal. The brine content and concentration vary from 5.71 to 13.94 wt% NaCl eq. Raman spectra of selected fluid inclusions revealed they are mainly composed of H2O (3500-3000 cm- 1) and subordinately CO2 both gaseous and liquid (1386 cm- 1 and 1281 cm- 1). Mineral inclusions are mainly represented by hematite with marker bands at 1321, 413, 293 and 227 cm- 1, subordinately quartz. Amethyst crystallized from medium- to low-temperature silica fluids (191-445 °C, 64-131 MPa) containing some amounts of CO2 and Fe at hydrothermal stage of post magmatic activity in Boudi (Morocco). Its possible depth of formation was calculated to be ca. 2.8-5.7 km.

Financial inclusion: Policies and practices

Directory of Open Access Journals (Sweden)

Thankom Arun

2015-12-01

Full Text Available As a key enabler for development, financial inclusion is firmly placed on the agenda of most governments as a key policy priority. Against this background, this round table provides a global and regional perspective on the policies and practices of financial inclusion. Using macro data, the collection reveals the diversity in the efforts towards achieving financial inclusion and the need for a progressive approach in financial inclusion. Further to this, the round table provides the regional perspectives on the policies and practices of financial inclusion in India, South Africa, and Australia.

Organic compounds in fluid inclusions of Archean quartz-Analogues of prebiotic chemistry on early Earth.

Science.gov (United States)

Schreiber, Ulrich; Mayer, Christian; Schmitz, Oliver J; Rosendahl, Pia; Bronja, Amela; Greule, Markus; Keppler, Frank; Mulder, Ines; Sattler, Tobias; Schöler, Heinz F

2017-01-01

The origin of life is still an unsolved mystery in science. Hypothetically, prebiotic chemistry and the formation of protocells may have evolved in the hydrothermal environment of tectonic fault zones in the upper continental crust, an environment where sensitive molecules are protected against degradation induced e.g. by UV radiation. The composition of fluid inclusions in minerals such as quartz crystals which have grown in this environment during the Archean period might provide important information about the first organic molecules formed by hydrothermal synthesis. Here we present evidence for organic compounds which were preserved in fluid inclusions of Archean quartz minerals from Western Australia. We found a variety of organic compounds such as alkanes, halocarbons, alcohols and aldehydes which unambiguously show that simple and even more complex prebiotic organic molecules have been formed by hydrothermal processes. Stable-isotope analysis confirms that the methane found in the inclusions has most likely been formed from abiotic sources by hydrothermal chemistry. Obviously, the liquid phase in the continental Archean crust provided an interesting choice of functional organic molecules. We conclude that organic substances such as these could have made an important contribution to prebiotic chemistry which might eventually have led to the formation of living cells.

Preparation, physicochemical characterization and release behavior of the inclusion complex of trans-anethole and β-cyclodextrin.

Science.gov (United States)

Zhang, Wenwen; Li, Xinying; Yu, Taocheng; Yuan, Lun; Rao, Gang; Li, Defu; Mu, Changdao

2015-08-01

Trans-anethole (AT) has a variety of antimicrobial properties and is widely used as food functional ingredient. However, the applications of AT are limited due to its low water solubility, strong odor and low physicochemical stability. Therefore, the aim of this work was to encapsulate AT with β-cyclodextrin (β-CD) for obtaining inclusion complex by co-precipitation method. The measurements effectively confirmed the formation of inclusion complex between AT and β-CD. The results showed that the inclusion complex presented new solid crystalline phases and was more thermally stable than the physical mixture and β-CD. The phase solubility study showed that the aqueous solubility of AT was increased by being included in β-CD. The calculated stability constant of inclusion complex was 1195M -1 , indicating the strong interaction between AT and β-CD. Furthermore, the release study suggested that β-CD provided the protection for AT against evaporation. The release behavior of AT from the inclusion complex was controlled. Copyright © 2015 Elsevier Ltd. All rights reserved.

INCLUSIVE CULTURE IN PRE-SCHOOL INSTITUTIONS

Directory of Open Access Journals (Sweden)

Irena NOVACHEVSKA

2011-04-01

Full Text Available Inclusive education is a rational concept that refers to the overall and long-term transformation of institutional systems in society, especially in education. Along with the transformation, a number of important and unresolved issues still appear in both theory and practice, as the duty of pre-school institutions and schools is to educate every student in the mainstream education system. One of the most important aspects of inclusion is the inclusive culture. Regardless of the good inclusive policy and practice, one cannot talk about successful inclusion without a properly developed inclusive institutional culture.This paper is a contribution to the research considering the development of inclusive culture in three preschool institutions. It is based on the thinking and attitudes of the pre­school staff toward the necessity of developing and nurturing an inclusive culture. Successful inclusion of pupils with special needs in the mainstream school system cannot be conceived without an inclusive culture.

3D imaging of vapour and liquid inclusions from the Mole Granite, Australia, using helical fluorescence tomography

Energy Technology Data Exchange (ETDEWEB)

Cauzid, J. [European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 220, 38043 Grenoble Cedex (France)], E-mail: jean.cauzid@esrf.fr; Philippot, P. [Geobiosphere Actuelle et Primitive, Institut de Physique du Globe de Paris, CNRS and Universite Denis Diderot, Case 89, 4 place Jussieu, 75252 Paris Cedex 05 (France); Bleuet, P. [European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 220, 38043 Grenoble Cedex (France); Simionovici, A. [Laboratoire de Geophysique Interne et Tectonophysique, BP 53, 38041 Grenoble Cedex 9 (France); Somogyi, A. [Synchrotron Soleil, DiffAbs beamline, Saint-Aubin, BP 48, 91192 Gif-sur-Yvette Cedex (France); Golosio, B. [Instituto di Matematica e Fisica, Universita di Sassari, 2 via Vienna, 07100 Sassari (Italy)

2007-08-15

World class Cu resources are concentrated in porphyry and epithermal ore deposits. Their formation remains partially understood, however, due to a lack of constraints on the partitioning properties of trace elements in general, and Cu in particular, between vapour and liquid phases evolved from boiling fluids at depth in the Earth's crust. Immiscible liquid and vapour fluid inclusions coexisting in a single quartz grain have been imaged in three dimensions by X-ray Fluorescence Computed Tomography (XFCT). Elemental spatial distributions confirm that Cu, and to a lesser extent As, partition into the vapour phase, whereas Mn, Fe, Zn, Br, Rb, Sr and Pb concentrate in the liquid inclusion. High resolution mapping of the vapour inclusions revealed that Cu is heterogeneously distributed at the scale of a single inclusion and is mostly concentrated as tiny daughter crystals.

3D imaging of vapour and liquid inclusions from the Mole Granite, Australia, using helical fluorescence tomography

Science.gov (United States)

Cauzid, J.; Philippot, P.; Bleuet, P.; Simionovici, A.; Somogyi, A.; Golosio, B.

2007-08-01

World class Cu resources are concentrated in porphyry and epithermal ore deposits. Their formation remains partially understood, however, due to a lack of constraints on the partitioning properties of trace elements in general, and Cu in particular, between vapour and liquid phases evolved from boiling fluids at depth in the Earth's crust. Immiscible liquid and vapour fluid inclusions coexisting in a single quartz grain have been imaged in three dimensions by X-ray Fluorescence Computed Tomography (XFCT). Elemental spatial distributions confirm that Cu, and to a lesser extent As, partition into the vapour phase, whereas Mn, Fe, Zn, Br, Rb, Sr and Pb concentrate in the liquid inclusion. High resolution mapping of the vapour inclusions revealed that Cu is heterogeneously distributed at the scale of a single inclusion and is mostly concentrated as tiny daughter crystals.

Irradiation history of meteoritic inclusions

DEFF Research Database (Denmark)

Wielandt, Daniel Kim Peel

Understanding the formation and earliest evolution of our solar system is a longstanding goal shared by cosmochemistry, astronomy and astrophysics. Meteorites play a key role in this pursuit, providing a ground truth against which all theories must be weighed. Chondritic meteorites are in essence...... extraterrestrial sediments that contain Calcium-Aluminium-rich Inclusions (CAIs) and chondrules that formed as individual objects during the earliest stages of solar system evolution. They later accreted together to form large bodies, after spending up to several million years in individual orbit around the proto...... of presolar and protosolar materials, as well as evidence for the former presence of over 10 extinct shortlived radionuclei of varying stability and provenance that play a key role in deciphering early solar system evolution. Some shortlived radionuclei, such as 60Fe (T½ 2.5 Myr), must have formed...

A note on fluid inclusion study of quartz from uraniferous migmatites from Sirsoti area, Sonbhadra district, Uttar Pradesh, India

International Nuclear Information System (INIS)

Ramana Murthy, K.V.; Shobhita, K.; Gorikhan, R.A.; Bhattacharya, A.K.

1993-01-01

Fluid inclusion study has been carried out on quartz from uraniferous migmatitic rocks of Sirsoti area of Sonbhadra District, Uttar Pradesh. The fluid inclusions in quartz are of two types viz. (i) H 2 O liquid + vapour and (ii) H 2 O liquid + CO 2 liquid + CO 2 gas. Homogenization temperatures of H 2 O liquid + vapour type inclusions indicate that the temperature of formation varied between 150-350degC. Ice melting temperatures indicate that the hydrothermal solutions were CO 2 -bearing with a salinity of 6-8% NaCl. A common range of homogenization temperature for both liquid-rich as well as vapour-rich inclusions provides evidence for the boiling of the ore fluids. (author). 5 refs., 7 figs

Fluid inclusion geothermometry

Science.gov (United States)

Cunningham, C.G.

1977-01-01

Fluid inclusions trapped within crystals either during growth or at a later time provide many clues to the histories of rocks and ores. Estimates of fluid-inclusion homogenization temperature and density can be obtained using a petrographic microscope with thin sections, and they can be refined using heating and freezing stages. Fluid inclusion studies, used in conjunction with paragenetic studies, can provide direct data on the time and space variations of parameters such as temperature, pressure, density, and composition of fluids in geologic environments. Changes in these parameters directly affect the fugacity, composition, and pH of fluids, thus directly influencing localization of ore metals. ?? 1977 Ferdinand Enke Verlag Stuttgart.

Becoming Inclusive: A Code of Conduct for Inclusion and Diversity.

Science.gov (United States)

Schmidt, Bonnie J; MacWilliams, Brent R; Neal-Boylan, Leslie

There are increasing concerns about exclusionary behaviors and lack of diversity in the nursing profession. Exclusionary behaviors, which may include incivility, bullying, and workplace violence, discriminate and isolate individuals and groups who are different, whereas inclusive behaviors encourage diversity. To address inclusion and diversity in nursing, this article offers a code of conduct. This code of conduct builds on existing nursing codes of ethics and applies to nursing students and nurses in both educational and practice settings. Inclusive behaviors that are demonstrated in nurses' relationships with patients, colleagues, the profession, and society are described. This code of conduct provides a basis for measureable change, empowerment, and unification of the profession. Recommendations, implications, and a pledge to action are discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

Architecture of Amylose Supramolecules in Form of Inclusion Complexes by Phosphorylase-Catalyzed Enzymatic Polymerization

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Jun-ichi Kadokawa

2013-07-01

Full Text Available This paper reviews the architecture of amylose supramolecules in form of inclusion complexes with synthetic polymers by phosphorylase-catalyzed enzymatic polymerization. Amylose is known to be synthesized by enzymatic polymerization using α-d-glucose 1-phosphate as a monomer, by phosphorylase catalysis. When the phosphorylase-catalyzed enzymatic polymerization was conducted in the presence of various hydrophobic polymers, such as polyethers, polyesters, poly(ester-ether, and polycarbonates as a guest polymer, such inclusion supramolecules were formed by the hydrophobic interaction in the progress of polymerization. Because the representation of propagation in the polymerization is similar to the way that a vine of a plant grows, twining around a rod, this polymerization method for the formation of amylose-polymer inclusion complexes was proposed to be named “vine-twining polymerization”. To yield an inclusion complex from a strongly hydrophobic polyester, the parallel enzymatic polymerization system was extensively developed. The author found that amylose selectively included one side of the guest polymer from a mixture of two resemblant guest polymers, as well as a specific range in molecular weights of the guest polymers poly(tetrahydrofuran (PTHF in the vine-twining polymerization. Selective inclusion behavior of amylose toward stereoisomers of chiral polyesters, poly(lactides, also appeared in the vine-twining polymerization.

SUPPORT IN INCLUSIVE EDUCATION

OpenAIRE

Belma Čičkušić; Ševala Tulumović; Selma Bakić; Salem Bakić

2016-01-01

In order for inclusive class to be successful, associates are of great help to teachers. Besides associates, teachers' specialization can be accomplished through educational seminars on the inclusion topic. However, information about inclusion, working with children with special needs, can also be found in scientific journals that offer more information on methods of working with children with special needs, didactic materials customized according to abilities of children. Aim of ...

Corundum-Hibonite Inclusions and the Environments of High Temperature Processing in the Early Solar System

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Needham, A. W.; Messenger, S.

2013-01-01

Calcium, Aluminum-rich inclusions (CAIs) are composed of the suite of minerals predicted to be the first to condense from a cooling gas of solar composition [1]. Yet, the first phase to condense, corundum, is rare in CAIs, having mostly reacted to form hibonite followed by other phases at lower temperatures. Many CAIs show evidence of complex post-formational histories, including condensation, evaporation, and melting [e.g. 2, 3]. However, the nature of these thermal events and the nebular environments in which they took place are poorly constrained. Some corundum and corundum-hibonite grains appear to have survived or avoided these complex CAI reprocessing events. Such ultra-refractory CAIs may provide a clearer record of the O isotopic composition of the Sun and the evolution of the O isotopic composition of the planet-forming region [4-6]. Here we present in situ O and Mg isotopic analyses of two corundum/hibonite inclusions that record differing formation histories.

Stiffening solids with liquid inclusions

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Style, Robert W.; Boltyanskiy, Rostislav; Allen, Benjamin; Jensen, Katharine E.; Foote, Henry P.; Wettlaufer, John S.; Dufresne, Eric R.

2015-01-01

From bone and wood to concrete and carbon fibre, composites are ubiquitous natural and synthetic materials. Eshelby’s inclusion theory describes how macroscopic stress fields couple to isolated microscopic inclusions, allowing prediction of a composite’s bulk mechanical properties from a knowledge of its microstructure. It has been extended to describe a wide variety of phenomena from solid fracture to cell adhesion. Here, we show experimentally and theoretically that Eshelby’s theory breaks down for small liquid inclusions in a soft solid. In this limit, an isolated droplet’s deformation is strongly size-dependent, with the smallest droplets mimicking the behaviour of solid inclusions. Furthermore, in opposition to the predictions of conventional composite theory, we find that finite concentrations of small liquid inclusions enhance the stiffness of soft solids. A straightforward extension of Eshelby’s theory, accounting for the surface tension of the solid-liquid interface, explains our experimental observations. The counterintuitive stiffening of solids by fluid inclusions is expected whenever inclusion radii are smaller than an elastocapillary length, given by the ratio of the surface tension to Young’s modulus of the solid matrix. These results suggest that surface tension can be a simple and effective mechanism to cloak the far-field elastic signature of inclusions.

Inclusive education and social exclusion

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Maria Luisa Bissoto

2013-01-01

Full Text Available The aim of this paper is critically examining assumptions underlying the Inclusive Education concept, arguing that this can only be effectively considered when understood in a broader context of social inclusion and exclusion. Methodologically, this article relies on international documents and bibliographic references about Inclusive Education, that have been chosen by systematize and characterize different social and educational inclusive practices, encouraging the elaboration of a general overview on this topic. The results of this analysis conclude that it is essential for Inclusive Education that educational institutions review their goals and reasons of social existence. In the concluding remarks it is argued that education is better understood as the act of encouraging and welcoming the efforts of individuals in their attempts to engage in social networking, which sustains life. This includes the acceptance of other reality interpretations and understanding that educational action cannot be restricted by the walls of institutions. It requires the participation of the whole community. Action perspectives likely to promote social inclusion and inclusive education are suggested.

The impact of a faculty training program on inclusive education and disability.

Science.gov (United States)

Moriña, Anabel; Carballo, Rafael

2017-12-01

This paper describes the knowledge gained by 20 faculty members following their participation in a training program on inclusive education and disability. The study, which was conducted at an university in Spain, aimed to design, implement and evaluate a program for training faculty members to respond in an inclusive manner to the needs of students with disabilities. An initial, formative and summative qualitative evaluation was carried out and four instruments were used for collecting the data: group and individual interviews, written open-ended questionnaires and observations. The data were analyzed inductively, using a category and code system. The results reveal that, after the training program, faculty considered what they had learned to be useful for their professional practice and highlighted that they felt better-informed and better-trained in relation to disability and were more aware of the needs of students with disabilities. Finally, in the conclusions section, the paper discusses the results in relation to those reported by other studies, and offers some recommendations for universities planning to implement training policies designed to build more inclusive learning environments. Published by Elsevier Ltd.

Microfluidic chips with multi-junctions: an advanced tool in recovering proteins from inclusion bodies.

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Yamaguchi, Hiroshi; Miyazaki, Masaya

2015-01-01

Active recombinant proteins are used for studying the biological functions of genes and for the development of therapeutic drugs. Overexpression of recombinant proteins in bacteria often results in the formation of inclusion bodies, which are protein aggregates with non-native conformations. Protein refolding is an important process for obtaining active recombinant proteins from inclusion bodies. However, the conventional refolding method of dialysis or dilution is time-consuming and recovered active protein yields are often low, and a cumbersome trial-and-error process is required to achieve success. To circumvent these difficulties, we used controllable diffusion through laminar flow in microchannels to regulate the denaturant concentration. This method largely aims at reducing protein aggregation during the refolding procedure. This Commentary introduces the principles of the protein refolding method using microfluidic chips and the advantage of our results as a tool for rapid and efficient recovery of active recombinant proteins from inclusion bodies.

RISKS OF INCLUSIVE EDUCATION

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M. R. Husnutdinova

2017-01-01

Full Text Available Introduction. Inclusion is a new and unfamiliar phenomenon for most of the Russians which is treated as ensuring equal access to education for all students taking into account a variety of their special educational needs and individual capabilities. Inclusive educational model began to take root in Russia without a broad public debate and today’s parents and teachers were not ready to the cardinal changes caused by transition to the new model of education. In this regard, the studying of directly educational process by consequences of inclusive training and education is urgent now.The aims of the research are the following: to identify the major risks that characterize the current stage of the implementation process of inclusion in the Russian educational organizations; to consider the main causes that lead to their occurrence; to present a comparative analysis of the views of respondents in comprehensive, inclusive and correctional schools. Methodology and research methods. The Sector Monitoring Studies of Moscow State University of Psychology & Education in 2010 and 2014 implemented a sociological study on the process of introduction of inclusion in the Russian schools. 200 teachers and 244 parents were interviewed in 2010; in 2014, in addition, 178 teachers and 386 parents were interviewed; 47 senior students including those with disabilities were interviewed too.Results. According to the results, the main concerns of the parents of students of comprehensive, inclusive and correctional schools are reduced to a few basic risks: lack of individual approach while teaching children with different educational needs, increased emotional pressure on the child, and child’s perception of the complexity of disability as an equal. These risks arise primarily because of the acute shortage of especially prepared-governmental teachers and socio-cultural, psychological unpreparedness of most contemporary children with disabilities to the perception of

Inclusão da competência interpessoal na formação do enfermeiro como gestor Inclusión de la competencia interpersonal en la formación del enfermero geston Inclusion of interpersonal competence in the formation of the nurse manager

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Denize Bouttelet Munari

2004-08-01

Full Text Available Este artigo se propõe a apresentar reflexões sobre a necessidade de incluir o desenvolvimento da competência interpessoal no processo de formação do enfermeiro gestor. Destaca as tendências da gestão contemporânea e a importância da construção de relacionamentos interpessoais como base para as ações do gestor. A inclusão da competência interpessoal, nesse sentido, pode influenciar na transformação da prática gerencial do enfermeiro e na formação de um líder que consiga avaliar e dimensionar os problemas de modo global e exercer o seu papel com segurança e transparência.El artículo presenta reflexiones sobre la necesidad para incluir el desarrollo de la capacidad interpersonal en el proceso de la formación de la enfermera de manejo. Destaca que la construcción de las relaciones interpersonales es recomendable a las buenas acciones de un encargado, ocurriendo con la interacción de la gente, pudiendo influenciar en la transformación de la práctica gerencial de este profesional y en la formación de un líder que obtenga para evaluar y dimensionar los problemas de la manera global y ejercer su papel con seguridad y transparencia.This article presents reflections about the necessity to include the development of interpersonal competence in the process of the nurse manager formation. It points up a trend of contemporary management and the importance of the construction of interpersonal relationships as base for the actions of a manager. The inclusion of interpersonal competence in this way can influence in the transformation of the nurse manager practice and in the formation of a leader who can evaluate and measure the problems in a global way and perform her/his role with security and transparency.

Foresighting for Inclusive Development

DEFF Research Database (Denmark)

Andersen, Allan Dahl; Andersen, Per Dannemand

2017-01-01

of policymaking processes affects the actual process with a focus on inclusion, and we discuss how it affects policy effectiveness and innovation system transformation. Our argument is that processes of policymaking must be inclusive to affect and transform innovation systems because a set of distributed actors...... in foresight cases in two emerging economies: Brazil and South Korea. We conclude that better systemic and innovation oriented foresight is needed to enhance inclusive development....

Effect of Sulfur in Steel on Transient Evolution of Inclusions During Calcium Treatment

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Liu, Yang; Zhang, Lifeng; Zhang, Ying; Duan, Haojian; Ren, Ying; Yang, Wen

2018-04-01

In the current study, the effect of S content in the molten steel on inclusions during calcium treatment was studied using an induction furnace. The calcium in steel decreased from 48 to 2 ppm, and the sulfur in steel changed a little with time. When sulfur content in steel was as low as 25 ppm during calcium treatment, inclusions shifted from CaO-Al2O3-CaS to Al2O3-CaO with about 35 pct CaO. When the sulfur increased over 90 ppm, more CaS-CaO formed just after the addition of calcium, and then the CaS content decreased from over 45 pct to lower than 15 pct and inclusions were mostly Al2O3-CaO-CaS and Al2O3-CaO with a high Al2O3 content. Thermodynamic calculation predicted the variation of the composition of inclusions, indicating good agreement with the measurement, while a certain deviation existed, especially for heats with 90 and 180 ppm sulfur. A reaction model was proposed for the formation of CaO and CaS, which considered the reaction between calcium vapor bubbles in the zone and the dissolved oxygen and sulfur in the molten steel, as described by a Langmuir-type adsorption isotherm with a reaction occurring on the remaining vacant sites. The variation of transient CaS inclusions was discussed based on the thermodynamic calculation and the morphology evolution of typical inclusions containing CaS.

Competence of Inclusive Practices: ICT and Inclusive Education in Professional Teacher Development

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Erika Viviana Laiton Zarate

2017-06-01

Full Text Available The objective of this study was to design the “Competence of Inclusive Practices” which was articulated to the route of the “ICT Competences for Professional Teacher Development,” of the Ministry of Education of Colombia (2013, and thus to fully evaluate 30 teachers of an educational institution in the city of Bucaramanga, in order to recognize their individual or collective training needs, and to formulate appropriate interventions. The research was supported theoretically in guidelines offered by the Ministry of Education of Colombia, the Index for Inclusive Education (Booth and Ainscow, 2011, and empirical researches developed in Latin American countries, including Colombia. The research approach was quantitative, with a descriptive design, which allowed to establish that Inclusive Practices Competence integrated pertinently postures of inclusive education and criteria of the functional framework of Information and Communication Technologies (ICT in education; in addition, it made it possible to know teachers’ perception of the level of competence in relation to the competence level they were (placed; they stated to be located at a low level (explorer in the development of skills for Inclusive Practices Competence.

Higher value films prepared from poly(vinyl alcohol) and amylose-fatty acid derivatives inclusion complexes

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Water soluble amylose fatty acid and fatty ammonium salt inclusion complexes (AIC) were prepared by jet cooked high amylose corn starch with water soluble salts of long chain fatty acids or fatty amines. The formation of AIC was confirmed by X-ray diffraction of freeze-dried samples. After dissoluti...

Recent HERMES results from inclusive and semi-inclusive hadron production

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Van Hulse Charlotte

2015-01-01

Full Text Available Hermes collected a wealth of data using the 27.6 GeV polarized Hera lepton beam and various pure, polarized and unpolarized, gaseous targets. This unique data set opens the door to various measurements sensitive to the multi-dimensional structure of the nucleon. Among them are two-hadron production in semi-inclusive deep-inelastic scattering on a transversely polarized target, providing access to different transverse-momentum-dependent distribution and fragmentation functions in a way complementary to single-hadron production. Also transverse-target single-spin asymmetries in inclusive electroproduction of charged pions and kaons have been recently extracted, complementing data from proton-proton collisions, where large, so far unexplained, asymmetries have been observed. From inclusive measurements on various nuclear targets, the Λ polarization is extracted, also here complementing measurements in proton-proton collisions.

Characteristics and Modification of Non-metallic Inclusions in Titanium-Stabilized AISI 409 Ferritic Stainless Steel

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Kruger, Dirk; Garbers-Craig, Andrie

2017-06-01

This study describes an investigation into the improvement of castability, final surface quality and formability of titanium-stabilized AISI 409 ferritic stainless steel on an industrial scale. Non-metallic inclusions found in this industrially produced stainless steel were first characterized using SEM-EDS analyses through the INCA-Steel software platform. Inclusions were found to consist of a MgO·Al2O3 spinel core, which acted as heterogeneous nucleation site for titanium solubility products. Plant-scale experiments were conducted to either prevent the formation of spinel, or to modify it by calcium treatment. Modification to spherical dual-phase spinel-liquid matrix inclusions was achieved with calcium addition, which eliminated submerged entry nozzle clogging for this grade. Complete modification to homogeneous liquid calcium aluminates was achieved at high levels of dissolved aluminum. A mechanism was suggested to explain the extent of modification achieved.

Deformation and fracture properties of metals with non-metallic inclusions; Verformung und Bruch von Metallen mit nichtmetallischen Einschluessen

Energy Technology Data Exchange (ETDEWEB)

Schmauder, S.; Soppa, E. [Stuttgart Univ. (Germany). Staatliche Materialpruefungsanstalt

1998-12-31

Microstructural effects due to formation of non-uniform lines of non-metallic inclusions in the matrix are examined with respect to their macro-, meso-, and micromechanical effects in the alloy Al(6061) reinforced by SiC inclusions. A comparative analysis of results obtained with various microstructures reveals essential differences in the formation of shear bands, stress peaks, and strain concentrations in the material structure. The maxima and the distribution of those field variables are determined not only by the arrangement of inclusions clusters in the stringers but also depend on the presence and number of single-particle inclusions in pure matrix material. The banding of the microstructure causes a strongly anisotropic behaviour in terms of stress and strain distributions. (orig./CB) [Deutsch] In diesem Beitrag werden Gefuegeeinfluesse aufgrund unterschiedlich starker zeiliger Anordnungen der Teilchen in der Matrix im Hinblick auf ihre makro-, meso- und mikromechanischen Auswirkungen am Beispiel einer SiC-teilchenverstaerkten Aluminiumlegierung Al(6061) untersucht. Ein Vergleich der Ergebnisse verschiedener Gefuege zeigt wesentliche Unterschiede hinsichtlich der Ausbildung von Scherbaendern, Spannungsspitzen und von Dehnungskonzentrationen im Werkstoffgefuege. Die Maxima und die Verteilung dieser Feldgroessen sind nicht nur abhaengig davon, wie die Teilchen in den Zeilen angeordnet sind, sondern auch davon, ob einzelne Teilchen in reinen Matrixbereichen vorhanden sind. Die Zeiligkeit des Gefueges fuehrt zu einem stark anisotropen Verhalten hinsichtlich Spannungs- und Dehnungsverteilungen. (orig.)

Removal of inclusions from silicon

Science.gov (United States)

Ciftja, Arjan; Engh, Thorvald Abel; Tangstad, Merete; Kvithyld, Anne; Øvrelid, Eivind Johannes

2009-11-01

The removal of inclusions from molten silicon is necessary to satisfy the purity requirements for solar grade silicon. This paper summarizes two methods that are investigated: (i) settling of the inclusions followed by subsequent directional solidification and (infiltration by ceramic foam filters. Settling of inclusions followed by directional solidification is of industrial importance for production of low-cost solar grade silicon. Filtration is reported as the most efficient method for removal of inclusions from the top-cut silicon scrap.

Financial inclusion: Policies and practices

OpenAIRE

Thankom Arun; Rajalaxmi Kamath

2015-01-01

As a key enabler for development, financial inclusion is firmly placed on the agenda of most governments as a key policy priority. Against this background, this round table provides a global and regional perspective on the policies and practices of financial inclusion. Using macro data, the collection reveals the diversity in the efforts towards achieving financial inclusion and the need for a progressive approach in financial inclusion. Further to this, the round table provides the regional ...

Supporting Teachers in Inclusive Education

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Alekhina S.V.

2015-03-01

Full Text Available The article regards the issues of support provision to teachers involved in inclusive education as the main requirement for successful realization of inclusion. The methodological framework used in the study is a resource approach. The article describes the ways of extending the means of supporting teachers. The article also arguments for consolidating all the educators of inclusive schools into inclusive teams equally interested in joint work of administration and educators of intervention programs.

Professional and private experience with persons with special needs and attitudes of teachers of regular schools towards inclusion

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Rajović Vera

2010-01-01

Full Text Available In this paper, we seek for the factors of formation of attitudes of primary school teachers towards inclusion of children who due to some sensory, bodily, mental disability or social deprivation have the need for additional support in development and learning. Research on attitudes towards inclusive education of children with special needs so far indicates that teachers of regular schools 'hesitate' in accepting children with special needs, stating as a reason the fact that they do not feel competent enough to work with them. However, the increase in teacher readiness to work with these children can be seen from the projects for the inclusion of these children that educate the teachers and envisage the support of the school expert team. This study was conducted with the aim of determining whether teacher's experience - either private or professional - with persons with disabilities distinguishes the respondents who exhibit more favourable attitudes towards inclusive education of these children from those with less favourable attitudes. The sample consisted of 105 teachers from five regular primary schools at the territory of Belgrade, 44.2% of whom declared that they had professional experience in working with students with special needs, while 40% of respondents had private experience with persons with developmental disabilities. The results (ANOVA indicate that professional experience with working with children with special needs does not significantly affect the formation and changing of attitudes of teachers of regular schools towards inclusive education. On the other hand, private experience with persons with developmental disabilities has a significant influence both on the attitude towards inclusion as a whole and towards all its components (cognitive, conative, the feeling of competence. Based on the obtained results, implications for the development of the curriculum for educating teachers for working with children with developmental

PIXE and light element analysis (C,N) in glass inclusions trapped in meteorites with the nuclear microprobe

International Nuclear Information System (INIS)

Varela, M.E.; Mosbah, M.; Metrich, N.; Duraud, J.P.; Kurat, G.

1999-01-01

Proton-induced X-ray emission (PIXE) and light element analysis have been performed with the nuclear microprobe at the Laboratoire Pierre Suee (Saclay-France) in glass inclusions of the carbonaceous chondrites: Allende, Kaba and Renazzo, and in the achondrite meteorite: Chassigny. Carbon contents in olivine of chondrules are below the nuclear reactions analysis (NRA) detection limit, however, glasses from glass inclusions hosted by these grains, contain an appreciable and highly variable quantities of carbon (200-1600 ppm). This could indicate variable amounts of C trapped during glass inclusion formation. On the other hand, nitrogen is present in highly variable amounts in glasses of both, chondrites and achondrites minerals. Its abundance, correlated with depth from the section surface which suggests loss of N during analyses and therefore the possible existence of a very mobile (volatile?) species. A chondritic Rb/Sr and K/Rb ratio obtained by PIXE analyses in the glass-bearing inclusions of the Chassigny meteorite points towards a primitive source for the glass precursor of Chassigny inclusions

INCLUSIVE EDUCATION IN ITALY

OpenAIRE

Voitkāne, Vita

2017-01-01

European member States implement Inclusive Education policies thus contributing to a sustainable, inclusive society, although each country is at a different stage in this process. Italy, one of the first countries to launch integrative learning, has set an example since the 1970s, although the quality of inclusive education is unpredictable due to many issues. Authors Cantoni and Panetta (2006) emphasize that, although the culture of integration in Italy exists, much needs to be done to impro...

Inclusion-Body Myositis: Diagnosis

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... for MDA Blog Donate Search MDA.org Close Inclusion-Body Myositis (IBM) Diagnosis As with other muscle diseases, a doctor diagnoses inclusion-body myositis (IBM) by considering the individual’s personal ...

Lending a Helping Hand at Work: A Multilevel Investigation of Prosocial Motivation, Inclusive Climate and Inclusive Behavior.

Science.gov (United States)

Nelissen, Philippe T J H; Hülsheger, Ute R; van Ruitenbeek, Gemma M C; Zijlstra, Fred R H

2017-09-01

Purpose People with disabilities often encounter difficulties at the workplace such as exclusion or unfair treatment. Researchers have therefore pointed to the need to focus on behavior that fosters inclusion as well as variables that are antecedents of such 'inclusive behavior'. Therefore the purpose of this study was to research the relationship between prosocial motivation, team inclusive climate and employee inclusive behavior. Method A survey was conducted among a sample of 282 paired employees and colleagues, which were nested in 84 teams. Employees self-rated prosocial motivation and team inclusive climate, their inclusive behavior was assessed by colleagues. Hypotheses were tested using multilevel random coefficient modeling. Results Employees who are prosocially motivated will display more inclusive behavior towards people with disabilities, and this relationship is moderated by team inclusive climate in such a way that the relationship is stronger when the inclusive climate is high. Conclusion This study shows that inclusive organizations, which value a diverse workforce, need to be aware of not only individual employee characteristics, but also team level climate to ensure the smooth integrations of people with disabilities into regular work teams.

Inclusion control in high-performance steels

International Nuclear Information System (INIS)

Holappa, L.E.K.; Helle, A.S.

1995-01-01

Progress of clean steel production, fundamentals of oxide and sulphide inclusions as well as inclusion morphology in normal and calcium treated steels are described. Effects of cleanliness and inclusion control on steel properties are discussed. In many damaging constructional and engineering applications the nonmetallic inclusions have a quite decisive role in steel performance. An example of combination of good mechanical properties and superior machinability by applying inclusion control is presented. (author)

Construction of a narrative network aimed at implementing inclusive processes

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Francesca Salis

2017-01-01

Full Text Available The concept of inclusion in its complex aspects aimed at overcoming barriers to learning and involvement has led this research in university, in the light of special pedagogy and didactics, on the basis of inclusion index parameters, detecting the levels of integrated planning with the territory. The purpose of this study is not limited to disability and to special education needs but goes further than that encompassing isolation and/or exclusions. As far as the university system is concerned, it becomes significant to enquire about the inclusion process, in this case by means of a narrative approach, bearing in mind that organizational and learning models, together with access modes may give rise to social exclusion.Università e territorio: costruzione di una rete narrativa per l’implementazione dei processi inclusiviIl costrutto di inclusione nelle sue complesse sfaccettature mirate al superamento delle barriere all’apprendimento e alla partecipazione, ha guidato il presente lavoro di ricerca in ambito universitario alla luce della pedagogia e didattica speciale, sulla base dei parametri dell’Index for Inclusion, rilevando i livelli di progettazione integrata con il territorio. Il suo raggio di azione non si limita alla disabilità ma abbraccia tutti i bisogni educativi speciali, e l’isolamento, la marginalizzazione e/o le esclusioni che ne derivano. Rispetto al sistema universitario è rilevante interrogarsi sul processo di inclusione, in questo caso sulla base dell’approccio narrativo, preso atto che il modello organizzativo e le modalità di accesso e formative possono essere causa di esclusione formativa e sociale.

Inclusion in a Polarised World

OpenAIRE

Freeman, Alan

2005-01-01

This paper on inclusion was presented to the at the 2005 summer school of DEEEP (Development Education Exchange in Europe Project), Härnösand - Sweden, 5 - 12 June 2005. It addresses the significance of the concept of world civilisation. It assesses how meaning may be attached to the concept of inclusion in an economically polarised world. It develops a critique of the conception of economic inclusion, by means of an exploration of linguistic inclusion and the notion of ‘disability’. ‘...

Diverse Perspectives on Inclusive School Communities

Science.gov (United States)

Tsokova, Diana; Tarr, Jane

2012-01-01

What is an inclusive school community? How do stakeholders perceive their roles and responsibilities towards inclusive school communities? How can school communities become more inclusive through engagement with individual perspectives? "Diverse Perspectives on Inclusive School Communities" captures and presents the voices of a wide…

EDUCATIONAL INCLUSION A VIEW FROM TEACHERS-TUTORS FOR BACCALAUREATE: CHALLENGES AND DEFIANCES

Directory of Open Access Journals (Sweden)

Irma Leticia Zapata-Rivera

2015-07-01

Full Text Available This article provide an overview of educational inclusion about the challenges and defiances of the PIT-ADIUAS UAS in the formation of the student, through the eyes of teachers-tutors baccalaureate Guasave Nocturna of the Universidad Autónoma de Sinaloa. The importance of the article lies in the documentary analysis of the documents and signed in his rift with the reality observed in the classroom by teachers and tutors. Its approach is developed from a mixed methodology under the case study approach, supported by documentary research techniques and social research (observation and interview. The results obtained and conclusions that the team arrives, intended to call attention to the university authorities to order to comply with one of the precepts unsigned: educational inclusion through teacher-tutor professionalism in the globe NEE students.

Teachers becoming inclusive practitioners

African Journals Online (AJOL)

, construct their identities in the light of inclusive education, and how they negotiate the tensions and contradictions emerging from the processof becoming inclusive practitioners. Central to this discussion is the understanding that teachers' ...

A review of social inclusion measures.

Science.gov (United States)

Coombs, Tim; Nicholas, Angela; Pirkis, Jane

2013-10-01

Social inclusion is crucial to mental health and well-being and is emphasised in Australia's Fourth National Mental Health Plan. There is a recognition that a measure of social inclusion would complement the suite of outcome measures that is currently used in public sector mental health services. This paper is an initial scope of candidate measures of social inclusion and considers their suitability for this purpose. We identified potential measures through searches of PsycINFO and Medline and a more general Internet search. We extracted descriptive and evaluative information on each measure identified and compared this information with a set of eight criteria. The criteria related to the measure's inclusion of four domains of social inclusion outlined in Australia's Fourth National Mental Health Plan, its usability within the public mental health sector and its psychometric properties. We identified 10 candidate measures of social inclusion: the Activity and Participation Questionnaire (APQ-6); the Australian Community Participation Questionnaire (ACPQ); the Composite Measure of Social Inclusion (CMSI); the EMILIA Project Questionnaire (EPQ); the Evaluating Social Inclusion Questionnaire (ESIQ); the Inclusion Web (IW); the Social and Community Opportunities Profile (SCOPE); the Social Inclusion Measure (SIM); the Social Inclusion Questionnaire (SIQ); and the Staff Survey of Social Inclusion (SSSI). After comparison with the eight review criteria, we determined that the APQ-6 and the SCOPE-short form show the most potential for further testing. Social inclusion is too important not to measure. This discussion of individual-level measures of social inclusion provides a springboard for selecting an appropriate measure for use in public sector mental health services. It suggests that there are two primary candidates, but neither of these is quite fit-for-purpose in their current form. Further exploration will reveal whether one of these is suitable, whether another

Inclusão digital via acessibilidade web | Digital inclusion via web accessibility

Directory of Open Access Journals (Sweden)

Cesar Augusto Cusin

2009-03-01

Full Text Available Resumo A natureza atual da web, que destaca a participação colaborativa dos usuários em diversos ambientes informacionais digitais, conduz ao desenvolvimento de diretrizes que enfocam a arquitetura da informação digital inclusiva para diferentes públicos nas mais diversas ambiências informacionais. A pesquisa propõe e objetiva um ambiente informacional digital inclusivo, visando apontar os elementos de acessibilidade que permitam a promoção da inclusão informacional digital, de forma a destacar os referenciais da Arquitetura da Informação Digital, de recomendações internacionais, com o olhar da Ciência da Informação e das novas tecnologias de informação e comunicação (TIC. Palavras-chave inclusão digital; web; acessibilidade; ciência da informação; arquitetura da informação. Abstract The current nature of the web, which highlights the collaborative participation of users in various digital informational environments, leads to the development of guidelines that focus on the digital inclusive information architecture for different audiences in diverse informational environments. The study proposes an inclusive digital information environment, aiming to establish the elements of accessibility that  enable the promotion of digital inclusion information in order to highlight the references of digital information architecture, the international recommendations, with the perspective of Information Science and the new information and communication technologies (ICT. Keywords digital inclusion; web; accessibility; information science; information architecture.

A Functional Core of IncA Is Required for Chlamydia trachomatis Inclusion Fusion.

Science.gov (United States)

Weber, Mary M; Noriea, Nicholas F; Bauler, Laura D; Lam, Jennifer L; Sager, Janet; Wesolowski, Jordan; Paumet, Fabienne; Hackstadt, Ted

2016-04-01

Chlamydia trachomatis is an obligate intracellular pathogen that is the etiological agent of a variety of human diseases, including blinding trachoma and sexually transmitted infections. Chlamydiae replicate within a membrane-bound compartment, termed an inclusion, which they extensively modify by the insertion of type III secreted proteins called Inc proteins. IncA is an inclusion membrane protein that encodes two coiled-coil domains that are homologous to eukaryotic SNARE (soluble N-ethylmaleimide-sensitive factor attachment receptor) motifs. Recent biochemical evidence suggests that a functional core, composed of SNARE-like domain 1 (SLD-1) and part of SNARE-like domain 2 (SLD-2), is required for the characteristic homotypic fusion of C. trachomatis inclusions in multiply infected cells. To verify the importance of IncA in homotypic fusion in Chlamydia, we generated an incA::bla mutant. Insertional inactivation of incA resulted in the formation of nonfusogenic inclusions, a phenotype that was completely rescued by complementation with full-length IncA. Rescue of homotypic inclusion fusion was dependent on the presence of the functional core consisting of SLD-1 and part of SLD-2. Collectively, these results confirm in vitro membrane fusion assays identifying functional domains of IncA and expand the genetic tools available for identification of chlamydia with a method for complementation of site-specific mutants. Chlamydia trachomatis replicates within a parasitophorous vacuole termed an inclusion. The chlamydial inclusions are nonfusogenic with vesicles in the endocytic pathway but, in multiply infected cells, fuse with each other to form a single large inclusion. This homotypic fusion is dependent upon the presence of a chlamydial inclusion membrane-localized protein, IncA. Specificity of membrane fusion in eukaryotic cells is regulated by SNARE (soluble N-ethylmaleimide sensitive factor attachment receptor) proteins on the cytosolic face of vesicles and target

Thermal and electronic charge transport in bulk nanostructured Zr0.25Hf0.75NiSn composites with full-Heusler inclusions

International Nuclear Information System (INIS)

Makongo, Julien P.A.; Misra, Dinesh K.; Salvador, James R.; Takas, Nathan J.; Wang, Guoyu; Shabetai, Michael R.; Pant, Aditya; Paudel, Pravin; Uher, Ctirad; Stokes, Kevin L.; Poudeu, Pierre F.P.

2011-01-01

Bulk Zr 0.25 Hf 075 NiSn half-Heusler (HH) nanocomposites containing various mole fractions of full-Heusler (FH) inclusions were prepared by solid state reaction of pre-synthesized HH alloy with elemental Ni at 1073 K. The microstructures of spark plasma sintered specimens of the HH/FH nanocomposites were investigated using transmission electron microscopy and their thermoelectric properties were measured from 300 K to 775 K. The formation of coherent FH inclusions into the HH matrix arises from solid-state Ni diffusion into vacant sites of the HH structure. HH(1-y)/FH(y) composites with mole fraction of FH inclusions below the percolation threshold, y∼0.2, show increased electrical conductivity, reduced Seebeck coefficient and increased total thermal conductivity arising from gradual increase in the carrier concentration for composites. A drastic reduction (∼55%) in κ l was observed for the composite with y=0.6 and is attributed to enhanced phonon scattering due to mass fluctuations between FH and HH, and high density of HH/FH interfaces. - Graphical abstract: Large reduction in the lattice thermal conductivity of bulk nanostructured half-Heusler/full-Heusler (Zr 0.25 Hf 075 NiSn/ Zr 0.25 Hf 075 Ni 2 Sn) composites, obtained by solid-state diffusion at 1073 K of elemental Ni into vacant sites of the half-Heusler structure, arising from the formation of regions of spinodally decomposed HH and FH phases with a spatial composition modulation of ∼2 nm. Highlights: → Bulk composites from solid state transformation of half-Heusler matrix through Ni diffusion. → Formation of coherent phase boundaries between half-Heusler matrix and full-Heusler inclusion. → Alteration of thermal and electronic transports with increasing full-Heusler inclusion. → Enhanced phonon scattering at half-Heusler/ full-Heusler phase boundaries.

An Arendtian perspective on inclusive education

DEFF Research Database (Denmark)

Korsgaard, Morten Timmermann

2016-01-01

Inclusive education currently appears to be undergoing a crisis and re- examination. This paper presents a new approach to thinking about inclusiveness in the school context. Many positions within inclusive education seem to take political, social and ethical perspectives as a starting point, which...... has allowed inclusive movements and initiatives around the world to succumb to neo-liberal policy-making and has neglected the development of an educational vocabulary that is theoretically and conceptually appropriate for confronting teachers’ central concerns regarding inclusive practices....... The concepts of suspension, bearing with strangers and enlarged thought inspired by Hannah Arendt provide a basis for a re-imagining of inclusive education and for outlining a future school in which inclusiveness is embedded in the very way we think and position ourselves as teachers and pupils...

Global Findex Database 2017 : Measuring Financial Inclusion and the Fintech Revolution

OpenAIRE

Demirguc-Kunt, Asli; Klapper, Leora; Singer, Dorothe; Ansar, Saniya; Hess, Jake

2018-01-01

The Global Findex database is the world's most comprehensive set of data on how people make payments, save money, borrow and manage risk. Launched in 2011, it includes more than 100 financial inclusion indicators in a format allowing users to compare access to financial services among adults worldwide -- including by gender, age and household income. This third edition of the database was compiled in 2017 using nationally representative surveys in more than 140 developing and high-income...

[Effect of β-cyclodextrin inclusion complex on transport of major components of Xiangfu Siwu decoction essential oil in Caco-2 cell monolayer model].

Science.gov (United States)

Xi, Jun-zuan; Qian, Da-wei; Duan, Jin-ao; Liu, Pei; Zhu, Yue; Zhu, Zhen-hua; Zhang, Li

2015-08-01

Although the essential oil of Xiangfu Siwu decoction (XFSWD) has strong pharmacological activity, its special physical and chemical properties restrict the clinical application and curative effect. In this paper, Xiangfu Siwu decoction essential oil (XFS-WO) was prepared by forming inclusion complex with β-cyclodextrin (β-CD). The present study is to investigate the effect of β-CD inclusion complex on the transport of major components of XFSWO using Caco-2 cell monolayer model, thus to research the effect of this formation on the absorption of drugs with low solubility and high permeability, which belong to class 2 in biopharmaceutics classification system. A sensitive and rapid UPLC-MS/MS method was developed for simultaneous quantification of senkyunolide A, 3-n-butylphthalide, Z-ligustilide, dehydrocostus lactone and α-cyperone, which are active compounds in XFSWO. The transport parameters were analyzed and compared in free oil and its β-CD inclusion complex. The result revealed that the formation of XFSWO/β-CD inclusion complex has significantly increased the transportation and absorption of major active ingredients than free oil. Accordingly, it can be speculated that cyclodextrin inclusion complex can improve bioavailability of poorly water-soluble drugs. Above all these mentioned researches, it provided foundation and basis for physiological disposition and pharmaceutical study of XFSWD.

Inclusive Education under Collectivistic Culture

Science.gov (United States)

Futaba, Yasuko

2016-01-01

This paper addresses how inclusive education under collective culture is possible. Inclusive education, which more-or-less involves changing the current schools, has been denied, doubted or distorted by both policy-makers and practitioners of general and special education in Japan. Main reason for the setback in inclusive education can be…

Inclusive Education in South Korea

Science.gov (United States)

Kim, Yong-Wook

2014-01-01

The purpose of this paper is to examine the current implementation of inclusive education in South Korea and discuss its challenges. The history of special education is first described followed by an introduction to policies relevant to special and inclusive education. Next, a critical discussion of the state of inclusive education follows built…

Roadmap for Inclusive Innovation

Data.gov (United States)

Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Roadmap for Inclusive Innovation data set shares the status of action items under the Roadmap for Inclusive Innovation. Each action or project has been assigned...

Effects of Mn and Al on the Intragranular Acicular Ferrite Formation in Rare Earth Treated C-Mn Steel

Science.gov (United States)

Song, Mingming; Song, Bo; Yang, Zhanbing; Zhang, Shenghua; Hu, Chunlin

2017-07-01

The influence of Al, Mn and rare earth (RE) on microstructure of C-Mn steel was investigated. The capacities of different RE inclusions to induce intragranular acicular ferrite (AF) formation were compared. Result shows that RE treatment could make C-Mn steel from large amounts of intragranular AF. Al killed is detrimental to the formation of intragranular AF in RE-treated C-Mn steel. An upper bainite structure would replace the AF when Al content increased to 0.027 mass %. The optimal Mn content to form AF is about 0.75-1.31 mass %. The effective RE inclusion which could induce AF nucleation is La2O2S. When patches of MnS are attached on the surface of La2O2S inclusion, AF nucleation capacity of RE-containing inclusion could enlarge obviously. The existence of manganese-depleted zone and low lattice misfit would be the main reason of La-containing inclusion inducing AF nucleation in C-Mn steel.

Politics of Inclusion and Empowerment

DEFF Research Database (Denmark)

Andersen, John; Siim, Birte

2004-01-01

identities. Politics of empowerment has to do with the agency and mobilisation dimension of social and political change. The title of the book "Politics of Inclusion and Empowerment" address the leitmotiv: namely to discuss plussumgame between politics of inclusion and politics of empowerment......The objective of the book is to analyse different politics of inclusion and empowerment and the different paradigms of inclusion/exclusion in order to underline the close link between politics of scoial equality and politics of recognition of ciultural difference. Politics of inclusion is thus...... theproductive/innovative linkage of politics of redistributuin and politics og resognition, whnich over a longer time span creates sustainable paths of democratic and social development, which increases the capacity to handle both conflicts about economic resources and life-chances and conflicts about...

A Comparative Study of the Inclusion Complexes of 2-[5'-benzylidene-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole and 2-[5'-(p-N,N-dimethylamino- benzylidene-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole withβ-Cyclodextrin

Directory of Open Access Journals (Sweden)

S. Panda

2011-01-01

Full Text Available The compounds 2-[5'-benzylidene-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole and 2-[5'-(p-N,N-dimethylamino- benzylidene-2'-phenyl-4'-oxo-1', 3'-thiazolidine]-1, 3-benzothiazole have been synthesized in their purest forms starting from 2-aminobenzothiazole. The inclusion complexes of the above compounds have been prepared with β-cyclodextrin to increase their solubility and bioaccessibility in polar medium. The formation of inclusion complexes have been ascertained by study of spectral characteristic before and after inclusion complex formation. The stability of inclusion complexes and nature of interaction between the host and guest are known from the determination of thermodynamic parameters. Further the antibacterial and antifungal activities of the compounds are determined which is found to increase significantly after inclusion complex formation

Inclusive differentiated instruction

Directory of Open Access Journals (Sweden)

Jerković Ljiljana S.

2017-01-01

Full Text Available Inclusive differentiated instruction is a new model of didactic instruction, theoretically described and established in this paper for the first time, after being experimentally verified through teaching of the mother tongue (instruction in reading and literature. Inclusive individually planned instruction is based on a phenomenological and constructivist didactic instructional paradigm. This type of teaching is essentially developmental and person-oriented. The key stages of inclusive differentiated instruction of literature are: 1 recognition of individual students' potential and educational needs regarding reading and work on literary texts; 2 planning and preparation of inclusive individually planned instruction in reading and literature; 3 actual class teaching of lessons thus prepared; and 4 evaluation of the student achievement following inclusive differentiated instruction in reading and literature. A highly important element of the planning and preparation of inclusive differentiated instruction is the creation of student profiles and inclusive individualized syllabi. Individualized syllabi specify the following: 1. a brief student profile; 2. the student position on the continuum of the learning outcomes of instruction in the Serbian language; 3. reverse-engineered macro-plan stages of instruction in the Serbian language (3.1. identifying expected outcomes and fundamental qualities of learners' work, 3.2. defining acceptable proofs of their realisation, 3.3. planning learning and teaching experiences, and 3.4. providing material and technical requisites for teaching; 4 the contents and procedure of individualized lessons targeting the student; 5 a plan of syllabus implementation monitoring and evaluation. The continuum of the learning outcomes of inclusive differentiated instruction in literature exists at three main levels, A, B and C. The three levels are: A reading techniques and learning about the main literary theory concepts; B

Effect of rigid inclusions on sintering

International Nuclear Information System (INIS)

Rahaman, M.N.; De Jonghe, L.C.

1988-01-01

The predictions of recent theoretical studies on the effect of inert, rigid inclusions on the sintering of ceramic powder matrices are examined and compared with experimental data. The densification of glass matrix composites with inclusion volume fractions of ≤0.15 can be adequately explained by Scherer's theory for viscous sintering with rigid inclusions. Inclusions cause a vast reduction in the densification rates of polycrystalline matrix composites even at low inclusion volume fractions. Models put forward to explain the sintering of polycrystalline matrix composites are discussed

Cleanliness distribution of high-carbon chromium bearing steel billets and growth behavior of inclusions during solidification

International Nuclear Information System (INIS)

Gu, C.; Bao, Y.; Lin, L.

2017-01-01

Variation of cleanliness and distribution of inclusions in thickness and width direction of highcarbon chromium bearing steel billets has been studied using total oxygen and nitrogen analysis and SEM/EDS, and the growth behavior of inclusions during solidification was studied with the help of solidification model. The region wit h relatively high total oxygen contents in the cross profile of billets is between inner arc side 3/16 and outer arc side 1/4; between left edge side 5/16 and right edge side 5/16. The formation sequence of inclusions is MgO-Al2O3 > TiN > MnS. MnS could wrap MgO-Al2O3 and reduces the damage to steel matrix caused by the latter, but generally could not effectively wrap TiN. Besides, TiN could wrap MgO-Al2O3 before MnS, which would weaken the protective capacity of MnS. Moreover, compared with MgO-Al2O3 inclusions, the sizes of TiN inclusions are generally larger. Thus the control of TiN inclusions should be strengthened. In hickness direction, the maximum size regions of TiN and MnS inclusions are inner arc side 1/3 and outer arc side 1/3; in width direction, the regions are edge side 1/3. During bearing processing, these regions and the regions with high total oxygen content should be avoided. [es

Cucurbit[6]uril p-xylylenediammonium diiodide decahydrate inclusion complex

Directory of Open Access Journals (Sweden)

Wei-Hao Huang

2008-07-01

Full Text Available The title inclusion complex, C36H36N24O12·C8H14N22+·2I−·10H2O, displays a large ellipsoidal deformation of the cucurbit[6]uril (CB[6] skeleton upon complex formation. The benzene ring of the cation is rotationally disordered between two orientations in a ratio of 3:1. The solvent H2O molecules form a hydrogen-bonded network by interaction with the carbonyl groups of CB[6] and the I− counterions. The crystal studied exhibited non-merohedral twinning. Both CB[6] and the cation are centrosymmetric.

Testing and Inclusive Schooling

DEFF Research Database (Denmark)

Morin, Anne; Hamre, Bjørn; Ydesen, Christian

Testing and Inclusive Schooling provides a comparative on seemingly incompatible global agendas and efforts to include all children in the general school system, Thus reducing exclusion. With an examination of the international testing culture and the politics of inclusion currently permeating...

The Politics of Inclusion and Empowerment

DEFF Research Database (Denmark)

Andersen, John; Siim, Birte

The objective of the book is to analyse different politics of inclusion and empowerment and the different paradigms of inclusion/exclusion in order to underline the close link between politics of scoial equality and politics of recognition of ciultural difference. Politics of inclusion is thus...... identities. Politics of empowerment has to do with the agency and mobilisation dimension of social and political change. The title of the book "Politics of Inclusion and Empowerment" address the leitmotiv: namely to discuss plussumgame between politics of inclusion and politics of empowerment...

Inclusion-initiated fracture model for ceramics

International Nuclear Information System (INIS)

Sung, J.; Nicholson, P.S.

1990-01-01

The fracture of ceramics initiating from a typical inclusion is analyzed. The inclusion is considered to have a thermal expansion coefficient and fracture toughness lower than those of the matrix and a Young's modulus higher than that of the matrix. Inclusion-initiated fracture is modeled for a spherical inclusion using a weight function method to compute the residual stress intensity factor for a part-through elliptical crack. The results are applied to an α-Al 2 O 3 inclusion embedded in a tetragonal ZrO 2 ceramic. The strength predictions agree well with experimental data

Sporulation of Bacillus sphaericus 2297: an electron microscope study of crystal-like inclusion biogenesis and toxicity to mosquito larvae.

Science.gov (United States)

Kalfon, A; Charles, J F; Bourgouin, C; de Barjac, H

1984-04-01

Sporulation of Bacillus sphaericus strain 2297 in a synchronous liquid culture was studied by electron microscopy. The t0 of sporulation occurred 7 h after the beginning of the lag phase. Crystal-like inclusions first appeared at t2 and reached their final size between t5 and t6. The release of the spore/inclusion complex occurred at about t15 (22 h after inoculation). Toxicity against Culex pipiens larvae was related to sporulation and appeared during the early stages of sporulation. The LC50 (24 h) decreased about 10(5)-fold between t0-2 and t7, in correlation with the formation of crystalline inclusions. Heat resistance of spores appeared later than toxicity.

Ca isotopes in refractory inclusions

International Nuclear Information System (INIS)

Niederer, F.R.; Papanastassiou, D.A.

1984-01-01

We report measurements of the absolute isotope abundance of Ca in Ca-Al-rich inclusions from the Allende and Leoville meteorites. Improved high precision measurements are reported also for 46 Ca. We find that nonlinear isotope effects in Ca are extremely rare in these inclusions. The absence of nonlinear effects in Ca, except for the effects in FUN inclusions, is in sharp contrast to the endemic effects in Ti. One fine-grained inclusion shows an excess of 46 Ca of (7 +- 1) per mille, which is consistent with addition of only 46 Ca or of an exotic (*) component with 46 Ca* approx. 48 Ca*. FUN inclusion EK-1-4-1 shows a small 46 Ca excess of (3.3 +- 1.0) per mille; this confirms that the exotic Ca components in EK-1-4-1 were even more deficient in 46 Ca relative to 48 Ca than is the case for normal Ca. The Ca in the Ca-Al-rich inclusions shows mass dependent isotope fractionation effects which have a range from -3.8 to +6.7 per mille per mass unit difference. This range is a factor of 20 wider than the range previously established for bulk meteorites and for terrestrial and lunar samples. Ca and Mg isotope fractionation effects in the Ca-Al-rich inclusions are common and attributed to kinetic isotope effects. (author)

Inclusive education: Ideas vs reality

Directory of Open Access Journals (Sweden)

Jovanović-Popadić Ana M.

2016-01-01

Full Text Available This paper discusses some of the key factors significant for the process of implementation of inclusive education in Serbia. After a brief review of the legal provisions regulating inclusive education in our country, the results of the research of attitudes towards inclusive education of teachers from six primary schools and one school for students with disabilities, as well as their experience, competencies, working conditions and opinions on consequences of inclusive education and education of children with developmental disabilities in specialized educational institutions are shown. Research was conducted in Krusevac, on a random sample of 60 teachers (51 teachers from primary schools and 9 special education teachers from schools for students with disabilities. We used two forms of questionnaires with twenty questions, and the results show predominantly negative attitudes towards inclusion in the majority of teachers in the sample. A significant percentage of respondents in both sub-samples considered that education of children with developmental disorders in specialized institutions (schools may give better results, primarily due to a lack of systematic support to teachers of primary schools in the process of implementing educational inclusion. The conclusion provides a critical overview of the current situation and presents the potential solutions to the problems that were identified during the research, and refer to the unsustainability of the current practice of inclusive education in Serbia.

Can we build inclusion?

DEFF Research Database (Denmark)

Kirkeby, Inge Mette; Grangaard, Sidse

2016-01-01

of some children with special needs. Hence the title – can we build inclusion? In the literature of Universal Design, accommodation and design features seldom reflect the less visible disabilities. The paper is based on a research project initiated to investigate how more or less space influences daily......Inclusion of children with special needs in kindergartens and preschools may be approached from different angles. This paper raises the question of whether the physical framework of kindergartens makes any difference for daily life at the kindergarten at all, and whether it can support inclusion...... on the answers in the interviews, we found support for answering the question in the title in the affirmative; we can build inclusion! This is because the teachers' experience indicated that, if there was sufficient space per child, there were fewer conflicts and the children managed to stay in the same activity...

C-O-H-S magmatic fluid system in shrinkage bubbles of melt inclusions

Science.gov (United States)

Robidoux, P.; Frezzotti, M. L.; Hauri, E. H.; Aiuppa, A.

2016-12-01

Magmatic volatiles include multiple phases in the C-O-H-S system of shrinkage bubbles for which a conceptual model is still unclear during melt inclusion formation [1,2,3,4]. The present study aims to qualitatively explore the evolution of the volatile migration, during and after the formation of the shrinkage bubble in melt inclusions trapped by olivines from Holocene to present at San Cristóbal volcano (Nicaragua), Central American Volcanic Arc (CAVA). Combined scanning electron microscope (SEM) and Raman spectroscopy observations allow to define the mineral-fluid phases inside typical shrinkage bubbles at ambient temperature. The existence of residual liquid water is demonstrated in the shrinkage bubbles of naturally quenched melt inclusion and this water could represents the principal agent for chemical reactions with other dissolved ionic species (SO42-, CO32-, etc.) and major elements (Mg, Fe, Cu, etc.) [4,5]. With the objective of following the cooling story of the bubble-inclusion system, the new methodological approach here estimate the interval of equilibrium temperatures for each SEM-Raman identified mineral phase (carbonates, hydrous carbonates, sulfurs, sulfates, etc.). Finally, two distinct mechanisms are proposed to describe the evolution of this heterogeneous fluid system in bubble samples at San Cristóbal which imply a close re-examination for similar volcanoes in subduction zone settings: (1) bubbles are already contracted and filled by volatiles by diffusion processes from the glass and leading to a C-O-H-S fluid-glass reaction enriched in Mg-Fe-Cu elements (2) bubbles are formed by oversaturation of the volatiles from the magma which is producing an immiscible metal-rich fluid. [1]Moore et al. (2015). Am. Mineral. 100, 806-823 [2]Wallace et al. (2015). Am. Mineral. 100, 787-794 [3]Lowenstern (2015). Am. Mineral. 100, 672-673 [4]Esposito, et al. (2016). Am. Mineral. 101, 1691-1708 [5]Kamenetsky et al. (2001). Earth Planet. Sci. Lett. 184, 685-702

Assessment of inclusive education

DEFF Research Database (Denmark)

Miller, Tanja

2014-01-01

The focus of this paper is on the way teachers, in teams can work with assessing the inclusive practice in their own classes. In 2012 a joint effort between CEPRA, teachers and school administrators from the municipality of Hjørring developed a dialog based model for continually assessing...... the quality of the learning environment in regard to inclusion – this model draws heavily on the logic and mindset of ECERS (Early child environment program). This article will relate the rationale of the assessment model called “Dialoger om Kvalitet” (dialogues on quality) to LSP’s definition of inclusion...

Role Of Banking-Sector To Inclusive Growth Through Inclusive Finance In Bangladesh

Directory of Open Access Journals (Sweden)

Sarker Sandip

2015-08-01

Full Text Available The study attempts to identify the relationship between the banking sector’s financing in agriculture and total agricultural output at national level. To assist the study, a simple linear regression model has been developed. The results suggest that there is a strong correlation between banking sectors’ financing in agriculture and agriculture output in Bangladesh. It is also evident that banking sector’s credits are significantly facilitating financial inclusion in Bangladesh. The model can be instrumental for developing countries that are seeking ways of inclusive growth. In addition; the study recommends some policy measures to overcome the challenges of financial inclusion with regards to the banking sector’s initiatives in financing agriculture in Bangladesh.

Inclusive Services Innovation Configuration

Science.gov (United States)

Holdheide, Lynn R.; Reschly, Daniel J.

2011-01-01

Teacher preparation to deliver inclusive services to students with disabilities is increasingly important because of changes in law and policy emphasizing student access to, and achievement in, the general education curriculum. This innovation configuration identifies the components of inclusive services that should be incorporated in teacher…

When Inclusion Is Innovation: An Examination of Administrator Perspectives on Inclusion in China

Science.gov (United States)

Hu, Bi Ying; Roberts, Sherron Killingsworth

2011-01-01

This article examines administrator perspectives of innovative services for the inclusion of young children with disabilities in regular preschool classrooms in China. Twelve directors from 12 pilot inclusion preschools in Beijing participated in this study. Qualitative interview results revealed the following subthemes: definition, advocacy,…

The electrochemical behaviour study of La{sup 3+} ion in fused chlorides bath. The LaNi{sub 5} formation; Estudo do comportamento eletroquimico do ion La{sup 3+} em meio a cloretos fundidos. A formacao de LaNi{sub 5}

Energy Technology Data Exchange (ETDEWEB)

Dias, Cristiane

2002-07-01

The electrochemical behaviour of La{sup 3+} ion was studied in fused chlorides bath, with purpose to obtain LaNi{sub 5} formation parameters. The lanthanum reduction/reoxidation mechanism and intermetallic compound formation were investigated by cyclic voltammetry, chronopotentiommetry and galvanostatic electrodeposition. The electrolyte employed was eutectic mixture NaCl-KCl (1:1) with anhydrous LaCl{sub 3} as solute, since 0,25 mol. L{sup -1} up to 2 mol. L{sup -1}, between 700 deg C and 800 deg C. The anhydrous LaCl{sub 3} was prepared by lanthanum chloride slow dehydration with HCl flow and heating until 300 deg C. Over molybdenum, results depicted that lanthanum electrochemical behaviour was quasi-reversible and electrodeposition occurred in a charge transfer step with three electrons. In nickel, intermetallic compound formation was observed by interdiffusion. The scanning electronic microscopy (SEM-EDS) and X ray diffraction analysis indicated that layers composition depend on temperature and solute concentration in fused bath. Mainly LaNi{sub 5} intermetallic compound was formed with LaCl{sub 3} anhydrous concentration of 2 mol. L{sup -1} at 750 deg C, with cathodic current density until 100 mA.cm{sup -2}. (author)

Fluid Force-Induced Detachment Criteria for Nonmetallic Inclusions Adhered to a Refractory/Molten Steel Interface

Science.gov (United States)

Dieguez Salgado, Uxia; Weiß, Christian; Michelic, Susanne K.; Bernhard, Christian

2018-05-01

Since nonmetallic inclusions (NMIs) in steel cannot be completely avoided, a greater understanding of their development and evolution during the steelmaking process is required. In particular, this includes the adhesion of microinclusions to the refractory/steel interface in the flow control system between the tundish and the mold. This phenomenon, commonly referred to as clogging, causes losses in productivity and product quality. Inclusions transported from the bulk melt to the boundary layer may adhere to the refractory/steel interface due to formation of a fluid cavity. A detailed model was derived for the detachment of NMIs adhering to a nozzle wall and is based on the local hydrodynamic conditions combined with the specific interfacial properties in the system consisting of the inclusions, the refractories, and the steel. The model is evaluated for three different application-oriented cases. This study has been focused on providing a better understanding of fluid flow in the near-wall region in order to reduce clogging during steelmaking.

Initial training for teachers of physical education to face reality of a school inclusion

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Victor Julierme Santos da Conceição

2009-09-01

Full Text Available This study, had as main objective to accomplish one it analyzes about the contribution of the critical-reflexive teaching in the physical education teachers’ initial formation, as the inclusion, in common class, of students with special educational needs. So that if it could approach the intentions foreseen for this investigation, it was used the beginnings of the participant research as methodological source. Being the subjects constituted by five academic of the course of Degree in physical education, in situation of teaching practice, of Santa Maria’s Federal University. Semi-structured interview, participant observation and documental analysis, they were the used instruments and registered in field diary in a period of a school semester of the year of 2005. The data send the conclusions for the trainees’ needs to observe the educational space, based in the critical reflection, for if they involve in the decisions that are part of this context. Facing this movement as an understanding of the world to your turn, contributing to understand the current process of the students’ inclusion with special educational needs. Lifting the problematic principal that refer the formative needs of the subject.

On Lipschitzian quantum stochastic differential inclusions

International Nuclear Information System (INIS)

Ekhaguere, G.O.S.

1990-12-01

Quantum stochastic differential inclusions are introduced and studied within the framework of the Hudson-Parthasarathy formulation of quantum stochastic calculus. Results concerning the existence of solutions of a Lipschitzian quantum stochastic differential inclusion and the relationship between the solutions of such an inclusion and those of its convexification are presented. These generalize the Filippov existence theorem and the Filippov-Wazewski Relaxation Theorem for classical differential inclusions to the present noncommutative setting. (author). 9 refs

Caught Up in the Past? Social Inclusion, Skills, and Vocational Education and Training Policy in England

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Fleckenstein, Timo; Lee, Soohyun Christine

2018-01-01

Since the mid-1990s, governments of different political persuasion have tried to reform VET policy to address problems in skills formation and social inclusion. Despite considerable policy activism, success has been somewhat limited, and England failed to overcome the problems associated with its liberal training regime. This article assesses the…

Numerical study of influence of inclusion movement on channel segregation in Fe- 0.21 wt% C- 0.1 wt% S alloy

International Nuclear Information System (INIS)

Liu, D R; Yang, Z P; Sun, Q Y; Wang, L P; Ma, B X

2016-01-01

A two-dimensional continuum model on solute and heat transport, and fluid flow is developed to numerically investigate the influence of inclusion movement on the development of channel segregation. A trajectory model is used to track the moving path of inclusion particles. Inclusion movement affects the flow field in simulation by means of interfacial friction coefficient. Simulations are performed on the Hebditch-Hunt casting. A parametric study is carried out to study the effects of with and without inclusions, and diameter (5 × 10 -6 m, 10 × 10 -6 m, 20 × 10 -6 m and 40 × 10 -6 m) of inclusions on channel segregation. It is found that the channel segregation is strengthened with the consideration of inclusion movement. Compared to other diameters, inclusions with diameter 20 × 10 -6 m are found to enhance the channel segregation. This is because the larger inclusions (40 × 10 -6 m) present a faster floating velocity that reduces the interaction time between inclusion upward movement and the development of solidification front, and then lessens the disturbance to solidification front that is important to the initialization of channel segregation. The upward movement of smaller inclusions (5 × 10 -6 m and 10 × 10 -6 m) cannot greatly increase the upward velocity of fluid flow. Therefore, the formation of channel segregation is less affected. (paper)

Study in aqueous solution of the praseodymium inclusion in β-cyclodextrin in 2 M of NaCl; Estudio en solucion acuosa de la inclusion del praseodimio en la β-ciclodextrina en 2 M de NaCl

Energy Technology Data Exchange (ETDEWEB)

De la Cruz M, N.

2013-07-01

In the fission of uranium to produce electricity, generated between the fission products which are the lanthanides and actinides that at any given time may come into contact with aqueous media, because of this, praseodymium was including in the β-cyclodextrin in order to increase the solubility and stability of praseodymium by forming inclusion complexes Praseodymium-β-cyclodextrin (Pr-β-Cd). The inclusion study was conducted in a proportion of praseodymium and β-cyclodextrin. Infrared spectra, Raman and X-ray diffraction showed the presence of praseodymium and β-cyclodextrin in the inclusion complex, in both proportions. The analysis by scanning electron microscopy confirmed the inclusion of praseodymium in βcyclodextrin. In general, the results of characterization obtained by these techniques show the formation of the inclusion complex. Furthermore, the behaviour of praseodymium inclusion in the β-cyclodextrin was studied in 2 M NaCl at 303 K and free-CO{sub 2} conditions. For this reason, we used two methods: spectrophotometric and potentiometric titration direct of praseodymium-β-cyclodextrin, the data were treated graphically and with the program SUPERQUAD, respectively. The values obtained for praseodymium by spectrophotometric method was: log β{sub 1}= -8.75 calculated graphically and with the potentiometric method, using program SUPERQUAD were logβ{sub 1,OH}= -8.73 ± 0.01 logβ{sub 1,2OH}= -18.27 ± 0.16 and logβ{sub 1,3OH}= -26.44 ± 0.02 obtained simultaneously. (Author)

Inclusion in Elementary Schools

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Susan Allan Galis

1995-10-01

Full Text Available This study of reform policy focused on inclusive education in the 1990s in the state of Georgia, United States of America. Program modifications including, individualizing instructional methods, adapting the instructional environment, and lowering maximum class size emerged as significant issues. We found that policies related to these areas were compounded by the less experienced educators not readily accepting change strategies for serving students. Apparently younger educators are engrossed in surviving daily routine and have difficulty coping with the complex demands of change. Regular education teachers have difficulty with the idea of inclusion. Legal aspects dealing inclusion need clarification, especially for regular education teachers.

Diversity, Equity, & Inclusion at Berkeley Lab

Science.gov (United States)

Berkeley Lab A-Z Index Directory Search Diversity, Equity, & Inclusion at Berkeley Lab Home Diversity & Inclusion Council Women Scientists & Engineers Council Employee Resource Groups -and culture of inclusion are key to attracting and engaging the brightest minds and furthering our

Jet inclusive cross sections

International Nuclear Information System (INIS)

Del Duca, V.

1992-11-01

Minijet production in jet inclusive cross sections at hadron colliders, with large rapidity intervals between the tagged jets, is evaluated by using the BFKL pomeron. We describe the jet inclusive cross section for an arbitrary number of tagged jets, and show that it behaves like a system of coupled pomerons

Supporting Students with Severe Disabilities in Inclusive Schools: A Descriptive Account From Schools Implementing Inclusive Practices

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Kurth, Jennifer A.; Lyon, Kristin J.; Shogren, Karrie A.

2015-01-01

The purpose of the present study was to investigate practices that support the inclusion of students with severe disabilities in the learning and social activities of inclusive K-8 schools to inform inclusive school reform research and practice. Eighteen K-8 students with severe disabilities in six schools recognized for their implementation of…

Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus.

Science.gov (United States)

Rincheval, Vincent; Lelek, Mickael; Gault, Elyanne; Bouillier, Camille; Sitterlin, Delphine; Blouquit-Laye, Sabine; Galloux, Marie; Zimmer, Christophe; Eleouet, Jean-François; Rameix-Welti, Marie-Anne

2017-09-15

Infection of cells by respiratory syncytial virus induces the formation of cytoplasmic inclusion bodies (IBs) where all the components of the viral RNA polymerase complex are concentrated. However, the exact organization and function of these IBs remain unclear. In this study, we use conventional and super-resolution imaging to dissect the internal structure of IBs. We observe that newly synthetized viral mRNA and the viral transcription anti-terminator M2-1 concentrate in IB sub-compartments, which we term "IB-associated granules" (IBAGs). In contrast, viral genomic RNA, the nucleoprotein, the L polymerase and its cofactor P are excluded from IBAGs. Live imaging reveals that IBAGs are highly dynamic structures. Our data show that IBs are the main site of viral RNA synthesis. They further suggest that shortly after synthesis in IBs, viral mRNAs and M2-1 transiently concentrate in IBAGs before reaching the cytosol and suggest a novel post-transcriptional function for M2-1.Respiratory syncytial virus (RSV) induces formation of inclusion bodies (IBs) sheltering viral RNA synthesis. Here, Rincheval et al. identify highly dynamic IB-associated granules (IBAGs) that accumulate newly synthetized viral mRNA and the viral M2-1 protein but exclude viral genomic RNA and RNA polymerase complexes.

Determination of neutral current couplings from neutrino-induced semi-inclusive pion and inclusive reactions

International Nuclear Information System (INIS)

Hung, P.Q.

1977-01-01

It is shown that by looking at data from neutrino-induced semi-inclusive pion and inclusive reactions on isoscalar targets along, one can determine completely the neutral current couplings. Predictions for various models are also presented. (Auth.)

Inclusive weak decays of charmed mesons

International Nuclear Information System (INIS)

Matthews, C.G.

1993-01-01

Inclusive analysis provide a different insight into the understanding of weak decay physics. This thesis experimentally determines inclusive decay predictions of charmed D mesons. Exclusive decay predictions are also used from a variety of theoretical models to make predictions about inclusive properties. Both experimental and theoretical realms benefit from the new techniques presented in this thesis. Inclusive properties derived are the multiplicity distributions, average multiplicities and inclusive branching ratios of charged particles, charged and neutral kaons, and charged pions. The center-of-mass momentum spectra of charged and neutral kaons are also obtained. Additionally, in the theoretical realm only, the inclusive properties of neutral pions, and the center-of-mass momentum spectra of charged and neutral pions are determined. The experimental analysis, which uses data from the mark II experiment at the Stanford Linear Accelerator Center, employs an unfold technique utilizing fold matrices to obtain the charged particle and kaon properties. A new enhanced unfold technique involving fold tensors obtains the first-ever results for the inclusive charged pion properties. The average strange quark contents and the average charged lepton multiplicities of the D + , D 0 and D + 8 are also presented. In the theoretical analysis, the exclusive decay mode predictions from the factorization model for Bauer, Stech and Wirbel; the quark diagram scheme of Chau and Cheng; and the QCD sum rules model of Block and Shifman are processed to determine inclusive predictions will lead to a better understanding of the model. The thesis also derives inclusive predictions from the D meson exclusive branching ratios compiled by the Particle Data Group

Isotope geochemistry of fluid inclusions in Permian halite with implications for the isotopic history of ocean water and the origin of saline formation waters

International Nuclear Information System (INIS)

Knauth, L.P.; Beeunas, M.A.

1986-01-01

deltaD and delta 18 O values have been determined for fluid inclusions in 45 samples of Permian halite. The inclusions are enriched in 18 O relative to the meteoric water line but are depleted in D relative to ocean water. Inclusions with the more positive delta-values coincide with the isotopic compositions expected for evaporating sea water which follows a hooked trajectory on a deltaD-delta 18 O diagram. Inclusions with more negative delta-values may represent more highly evaporated sea water but probably reflect synsedimentary or diagenetic mixing to those of a modern evaporite pan to indicate that Permian sea water was isotopically similar to modern sea water. Connate evaporite brines can have negative delta-values because of the probable hooked isotope trajectory of evaporating sea water and/or synsedimentary mixing of evaporite brines with meteoric waters. (author)

From exclusion to self-inclusion of women in ICT. Motivations, enablers and mechanisms of self-inclusion

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Núria Verges Bosch

2012-11-01

Full Text Available Research on the participation of women in ICT shows that the gender digital divide persists. Given that, most studies continue to focus on explaining the mechanisms of exclusion of women from ICT. In this article I propose a paradigm shift from exclusion to inclusion. I go beyond inclusion by conceptualizing and analysing the process of self-inclusion of women in ICT from a purposive sample of women artistic and computer technologists. The results are based on the qualitative analysis of interviews and focus groups, in which I aim to answer three main questions: What motivated their self-inclusion? What enablers did they encounter? What mechanisms did they follow and activate to self-include in ICT? The main results show, first, that the motivations for pleasure are predominant, but often complemented by other utilitarian motivations. Second, a set of enablers facilitate women’s self-inclusion in ICT, including gender policies. Finally, I discuss a number of mechanisms of self-inclusion that go beyond learning that include doing and undoing gender.

Inclusive outreach practices in Palaeontology: Inclusive-Coworking

Science.gov (United States)

García-Frank, Alejandra; Gomez-Heras, Miguel; Fesharaki, Omid

2017-04-01

Previous experiences with people with both physical and intellectual functional diversity around palaeontological issues have demonstrated the important value of science outreach directed to people with disabilities. The aforementioned practices act twofold: as a learning tool and also improving the quality of life of the participants and thus, their self-image. All these pioneer experiences were the first step in a process of developing new attitudes contributing the 2030 Agenda for Sustainable Development of United Nations, where among the 17 goals proposed an effective social inclusion of people with disabilities is required. For this, real inclusive practices in geological outreach are imperious. A close cooperation with all the parts (researchers and participants), in a kind of coworking attitude is needed. This Inclusive-Coworking is considered in the sense of social gathering in order to share equal values and look for the synergy that this different outlook implies. And what is more important: the change of role of the previously learners into an active part of the scientific outreach, providing the adequate methodology for that. The offer of non-formal learning activities normally includes the participation of university professors and researchers in Science Week editions. During the 2016 session in Madrid, four adults with intellectual disability who were participants in the previous edition, contributed in the palaeontological workshop. They were in charge of four of the eight modules explaining the origin of fossils and how to collect them, the evolution of equids' limbs, and the main dentition types in vertebrates to the twenty 16 year old secondary students who attended the workshop. During the development of the experience all the students were pleased with the inclusive approach, and the interaction of all participants was fruitful. Although the explanations took a bit more time when made by our functional diverse fellows, all the abstracts concepts

Deploying and implementing Inclusive Physical Education

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Eliana Lúcia Ferreira

2014-04-01

Full Text Available Physical Education, as a curricular component of basic education, is not indifferent to the movement of Inclusive physical education. Differentiated bodies are conquering new social spaces. Our aim through this investigation is to identify the main historical practices regarding Brazilian Policy of Inclusive Education and to point out proposals to implement inclusive Physical education. Our methodology consists of a descriptive study based on two main axes. The first axis is related to a historical discussion whose source was national documents of reference about Inclusive Physical Education. The second axis is related to the experience of 2000 teachers; we have the occasion to analyze their practices on the subject of Inclusive physical education. As a result, this investigation also develops a proposal to inclusive physical education; this proposal is established in another dimension and understanding of work and movement. Concerning the final considerations we suggest a disruption with already crystallized bodily practices and we suggest actions respecting individual differences. Moreover, we point out the fact that Inclusive Physical Education has advocated another meaning for the body, in favor of a more collective physical education and searching for activities in which individuality prevails.

Origin and timing of Dauphiné twins in quartz cement in fractured sandstones from diagenetic environments: Insight from fluid inclusions

Science.gov (United States)

Fall, András; Ukar, Estibalitz; Laubach, Stephen E.

2016-09-01

Electron backscattered diffraction techniques (EBSD) show that Dauphiné twins in quartz are widespread in many tectonometamorphic environments. Our study documents that under diagenetic temperatures (fluid inclusions. Fracture wall-parallel and wall-normal inclusion trails contain coexisting aqueous and hydrocarbon gas inclusions, so homogenization temperatures of aqueous inclusions record true trapping temperatures. Inclusions in alignments normal to fracture walls are large and irregularly shaped compared to those aligned parallel to walls, but both show similar liquid-to-vapor ratios. Stacking transmitted light images with scanning electron microscope cathodoluminescence (SEM-CL) and EBSD images demonstrates that Dauphiné twin boundaries are localized along wall-normal inclusion trails. Trapping temperatures for wall-normal inclusion trails are usually higher than those aligned parallel to the fracture wall. Wall-normal fluid inclusion assemblage temperatures typically match the highest temperatures of wall-parallel assemblages trapped during sequential widening, but not necessarily the most recent. In context of burial histories for these samples, this temperature pattern implies that wall-normal assemblages form at discrete times during or after crack-seal fracture widening. Localization in isolated, potentially high-stress quartz deposits in fractures is compatible with a mechanical origin for these Dauphiné twins. Punctuated temperature values and discrepant sizes and shapes of inclusions in wall-normal trails implies that twinning is a by-product of the formation of the wall-normal inclusion assemblages. The association of Dauphiné twins and fluid inclusion assemblages from which temperature and possibly timing can be inferred provides a way to research timing as well as magnitude of paleostress in some diagenetic settings.

Understanding Inclusion in Cyprus

Science.gov (United States)

Mamas, Christoforos

2013-01-01

This paper provides a framework for understanding inclusion in Cyprus. The evidence base is the result of a six-month qualitative research study in five Cypriot mainstream primary schools. Despite the rhetoric in favour of inclusion, it seems that the Cypriot educational system is still highly segregating in its philosophy and does not fully…

When social inclusion is not enough: Implicit expectations of extreme inclusion in borderline personality disorder.

Science.gov (United States)

De Panfilis, Chiara; Riva, Paolo; Preti, Emanuele; Cabrino, Chiara; Marchesi, Carlo

2015-10-01

Increasing evidence suggests that individuals with borderline personality disorder (BPD) might feel rejected even when socially included by others. A psychological mechanism accounting for this response bias could be that objective social inclusion violates BPD patients' underlying implicit needs of "extreme" inclusion. Thus, this study investigated whether, during interpersonal exchanges, BPD patients report more rejection-related negative emotions and less feelings of social connection than controls unless they are faced with conditions of extreme social inclusion. Sixty-one BPD patients and 61 healthy controls completed a modified Cyberball paradigm. They were randomly assigned to a condition of ostracism, social inclusion, or overinclusion (a proxy for extreme social inclusion). They then rated their emotional states and feelings of social connection immediately and 20 min after the game. BPD patients reported greater levels of negative emotions than controls in the ostracism and the inclusion conditions, but not when overincluded. Furthermore, only for BPD participants was overinclusion associated with experiencing less negative emotions than the ostracism condition. However, BPD patients reported lower feelings of social connection than controls in any experimental situation. Thus, in BPD, a laboratory condition of "overinclusion" is associated with a reduction of negative emotions to levels comparable to those of control participants, but not with similar degrees of social connection. These results suggest that for BPD patients, even "including contexts" activate feelings of rejection. Their implicit expectations of idealized interpersonal inclusion may nullify the opportunity of experiencing "real" social connection and explain their distorted subjective experiences of rejection. (c) 2015 APA, all rights reserved).

A Study on the Nonmetallic Inclusion Motions in a Swirling Flow Submerged Entry Nozzle in a New Cylindrical Tundish Design

Science.gov (United States)

Ni, Peiyuan; Ersson, Mikael; Jonsson, Lage Tord Ingemar; Jönsson, Pär Göran

2018-04-01

Different sizes and shapes of nonmetallic inclusions in a swirling flow submerged entry nozzle (SEN) placed in a new tundish design were investigated by using a Lagrangian particle tracking scheme. The results show that inclusions in the current cylindrical tundish have difficulties remaining in the top tundish region, since a strong rotational steel flow exists in this region. This high rotational flow of 0.7 m/s provides the required momentum for the formation of a strong swirling flow inside the SEN. The results show that inclusions larger than 40 µm were found to deposit to a smaller extent on the SEN wall compared to smaller inclusions. The reason is that these large inclusions have Separation number values larger than 1. Thus, the swirling flow causes these large size inclusions to move toward the SEN center. For the nonspherical inclusions, large size inclusions were found to be deposited on the SEN wall to a larger extent, compared to spherical inclusions. More specifically, the difference of the deposited inclusion number is around 27 pct. Overall, it was found that the swirling flow contains three regions, namely, the isotropic core region, the anisotropic turbulence region and the near-wall region. Therefore, anisotropic turbulent fluctuations should be taken into account when the inclusion motion was tracked in this complex flow. In addition, many inclusions were found to deposit at the SEN inlet region. The plotted velocity distribution shows that the inlet flow is very chaotic. A high turbulent kinetic energy value of around 0.08 m2/s2 exists in this region, and a recirculating flow was also found here. These flow characteristics are harmful since they increase the inclusion transport toward the wall. Therefore, a new design of the SEN inlet should be developed in the future, with the aim to modify the inlet flow so that the inclusion deposition is reduced.

The Inclusion of Inclusive Education in International Development: Lessons from Papua New Guinea

Science.gov (United States)

Le Fanu, Guy

2013-01-01

A new "inclusive" curriculum has been introduced in Papua New Guinea, with significant levels of support from a bilateral development agency. The curriculum is inclusive in the sense that it is designed to meet the diverse, complex, and ever-changing needs of students. Research indicates the curriculum has been shaped by various…

Origin and Timing of Dauphiné Twins Using Fluid Inclusions in Quartz-Cement Fractures in Sandstones from Diagenetic Environments

Science.gov (United States)

Fall, A.; Ukar, E.; Laubach, S.

2016-12-01

a by-product of the formation of the wall-normal inclusion trails.

Inclusion in the Workplace - Text Version | NREL

Science.gov (United States)

Careers » Inclusion in the Workplace - Text Version Inclusion in the Workplace - Text Version This is the text version for the Inclusion: Leading by Example video. I'm Martin Keller. I'm the NREL of the laboratory. Another very important element in inclusion is diversity. Because if we have a

Inclusion Complexes of Sunscreen Agents with β-Cyclodextrin: Spectroscopic and Molecular Modeling Studies

Directory of Open Access Journals (Sweden)

Nathir A. F. Al-Rawashdeh

2013-01-01

Full Text Available The inclusion complexes of selected sunscreen agents, namely, oxybenzone (Oxy, octocrylene (Oct, and ethylhexyl-methoxycinnamate (Cin with β-cyclodextrin (β-CD were studied by UV-Vis spectroscopy, differential scanning calorimetry (DSC, 13C NMR techniques, and molecular mechanics (MM calculations and modeling. Molecular modeling (MM study of the entire process of the formation of 1 : 1 stoichiometry sunscreen agent/β-cyclodextrin structures has been used to contribute to the understanding and rationalization of the experimental results. Molecular mechanics calculations, together with 13C NMR measurements, for the complex with β-CD have been used to describe details of the structural, energetic, and dynamic features of host-guest complex. Accurate structures of CD inclusion complexes have been derived from molecular mechanics (MM calculations and modeling. The photodegradation reaction of the sunscreen agents' molecules in lotion was explored using UV-Vis spectroscopy. It has been demonstrated that the photostability of these selected sunscreen agents has been enhanced upon forming inclusion complexes with β-CD in lotion. The results of this study demonstrate that β-CD can be utilized as photostabilizer additive for enhancing the photostability of the selected sunscreen agents' molecules.

Sound absorption enhancement of nonwoven felt by using coupled membrane - sonic crystal inclusion

Science.gov (United States)

Fitriani, M. C.; Yahya, I.; Harjana; Ubaidillah; Aditya, F.; Siregar, Y.; Moeliono, M.; Sulaksono, S.

2016-11-01

The experimental results from laboratory test on the sound absorption performance of nonwoven felt with an array thin tubes and sonic crystal inclusions reported in this paper. The nonwoven felt sample was produced by a local company with 15 mm in its thickness and 900 gsm. The 6.4 mm diameter plastic straw was used to construct the thin tubes array while the sonic crystal is arranged in a 4 × 4 lattice crystal formation. It made from a PVC cylinder with 17 mm and 50 mm in diameter and length respectively. All cylinders have two holes positioned on 10 mm and 25 mm from the base. The results show that both treatments, array of thin tube and sonic crystal inclusions are effectively increased the sound absorption coefficient of the nonwoven felt significantly especially in the low frequency range starting from 200Hz.

Hydrocarbon migration and accumulation in the Upper Cretaceous Qingshankou Formation, Changling Sag, southern Songliao Basin: Insights from integrated analyses of fluid inclusion, oil source correlation and basin modelling

Science.gov (United States)

Dong, Tian; He, Sheng; Wang, Dexi; Hou, Yuguang

2014-08-01

The Upper Cretaceous Qingshankou Formation acts as both the source and reservoir sequence in the Changling Sag, situated in the southern end of the Songliao Basin, northeast China. An integrated approach involving determination of hydrocarbon charging history, oil source correlation and hydrocarbon generation dynamic modeling was used to investigate hydrocarbon migration processes and further predict the favorable targets of hydrocarbon accumulations in the Qingshankou Formation. The hydrocarbon generation and charge history was investigated using fluid inclusion analysis, in combination with stratigraphic burial and thermal modeling. The source rocks began to generate hydrocarbons at around 82 Ma and the hydrocarbon charge event occurred from approximately 78 Ma to the end of Cretaceous (65.5 Ma) when a large tectonic uplift took place. Correlation of stable carbon isotopes of oils and extracts of source rocks indicates that oil was generated mainly from the first member of Qingshankou Formation (K2qn1), suggesting that hydrocarbon may have migrated vertically. Three dimensional (3D) petroleum system modeling was used to evaluate the processes of secondary hydrocarbon migration in the Qingshankou Formation since the latest Cretaceous. During the Late Cretaceous, hydrocarbon, mainly originated from the Qianan depression, migrated laterally to adjacent structural highs. Subsequent tectonic inversion, defined as the late Yanshan Orogeny, significantly changed hydrocarbon migration patterns, probably causing redistribution of primary hydrocarbon reservoirs. In the Tertiary, the Heidimiao depression was buried much deeper than the Qianan depression and became the main source kitchen. Hydrocarbon migration was primarily controlled by fluid potential and generally migrated from relatively high potential areas to low potential areas. Structural highs and lithologic transitions are potential traps for current oil and gas exploration. Finally, several preferred hydrocarbon

Utilizing the Critical Inclusive Praxis: The Voyage of Five Selected School Principals in Building Inclusive School Cultures

Science.gov (United States)

Osiname, Ayodeji Tolulope

2018-01-01

This article integrates relevant literature with the lived experiences of five school principals regarding how they utilized different leadership styles to build an inclusive school culture. The conceptual framework--a Critical Inclusive Praxis, including culture, change, leadership, inclusion and challenge--provided a base for the literature and…

Supporting the Transition to Inclusive Education: Teachers' Attitudes to Inclusion in the Seychelles

Science.gov (United States)

Main, Susan; Chambers, Dianne J.; Sarah, Paulette

2016-01-01

The inclusion of children with disability in regular classroom settings has been identified worldwide as crucial to the provision of effective education for all children and to the creation of more inclusive societies. To this end there has been significant focus on pre-service and in-service teacher education to ensure that teachers are…

How Bureaucracy Promotes Inclusive Organizing

DEFF Research Database (Denmark)

Holck, Lotte

Diversity literature in general and Feminist in particular have long promoted alternatives to bureaucracy on the premise that this form of governance is far from gender- and race-neutral, and that inclusive organizing necessitate a flatter, decentralized and more ‘organic’ set-up (Ferguson 1984...... and opportunities conducive to their inclusion. Guided by Ashcraft (2001) concept of organized dissonance, this paper explores how the combination of apparent incongruent elements of stability/flexibility and formality/informality might offer a passage for inclusive organizing....

L-arginine mediated renaturation enhances yield of human, α6 Type IV collagen non-collagenous domain from bacterial inclusion bodies.

Science.gov (United States)

Gunda, Venugopal; Boosani, Chandra Shekhar; Verma, Raj Kumar; Guda, Chittibabu; Sudhakar, Yakkanti Akul

2012-10-01

The anti-angiogenic, carboxy terminal non-collagenous domain (NC1) derived from human Collagen type IV alpha 6 chain, [α6(IV)NC1] or hexastatin, was earlier obtained using different recombinant methods of expression in bacterial systems. However, the effect of L-arginine mediated renaturation in enhancing the relative yields of this protein from bacterial inclusion bodies has not been evaluated. In the present study, direct stirring and on-column renaturation methods using L-arginine and different size exclusion chromatography matrices were applied for enhancing the solubility in purifying the recombinant α6(IV)NC1 from bacterial inclusion bodies. This methodology enabled purification of higher quantities of soluble protein from inclusion bodies, which inhibited endothelial cell proliferation, migration and tube formation. Thus, the scope for L-arginine mediated renaturation in obtaining higher yields of soluble, biologically active NC1 domain from bacterial inclusion bodies was evaluated.

Theoretical investigation on the inclusion of TCDD with β-cyclodextrin by performing QM calculations and MD simulations

International Nuclear Information System (INIS)

Pan, Wenxiao; Zhang, Dongju; Zhan, Jinhua

2011-01-01

Highlights: → We study the inclusion mechanism of TCDD with β-CD by theoretical methods. → Clearly, the formation of inclusion complex is an energetically driven process. → The inclusion complex can be detected by IR and Raman techniques. → The results imply that β-CD may be used as a host molecule to enrich TCDD molecules. - Abstract: The rapid enrichment and detection of trace polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are currently challenging issues in the field of environmental science. In this paper, by performing quantum chemistry (QM) calculations and molecular dynamics (MD) simulations, we studied the inclusion complexation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a representative PCDD molecule, with β-cyclodextrin (β-CD), one of the widely used compounds in supramolecular chemistry. The calculated results reveal that the stable inclusion complex can be formed in both the gas phase and solvent, which proposes that β-CD may serve as a potential substrate enriching TCDD. The calculated vibrational spectra indicate that the infrared (IR) and Raman spectroscopy may be suitable for the detection of β-CD-modified TCDD. The present theoretical results may be informative to environmental scientists who are devoting themselves to developing effective methods for detection and treatment of POPs.

Analysis of I-Br-Cl in single fluid inclusions by LA-ICP-MS

Science.gov (United States)

Giehl, C.; Fusswinkel, T.; Beermann, O.; Garbe-Schönberg, D.; Scholten, L.; Wagner, T.

2017-12-01

Halogens are excellent tracers of hydrothermal fluid sources and in-situ LA-ICP-MS analysis of Cl and Br in single fluid inclusions has provided fundamentally new insight into hydrothermal fluid flow and ore formation. There is mounting evidence that enrichment and depletion of Br relative to Cl may be caused by a number of processes beyond seawater evaporation and halite dissolution which cannot be discriminated on the basis of Br/Cl ratios alone. Expanding the analytical capabilities of fluid inclusion LA-ICP-MS analysis to include iodine would allow to discern between selective and coupled enrichment processes of Cl, Br and I, even in geologically complex samples that are inaccessible to bulk extraction techniques. We present iodine concentration data determined by LA-ICP-MS analysis of synthetic fluid inclusions, using the Sca17 scapolite reference material for external standardization (Seo et al., 2011). Iodine concentrations in Sca17 were determined using the Durango apatite standard. Four starting solutions containing I (0.3, 1.5, 27, 78 µg/g), Br (941, 1403, 2868, 4275 µg/g), Na (30.7, 94.7 mg/g), and Cl (50, 137 mg/g) (analyzed by ICP-OES and ICP-MS at CAU Kiel) were prepared by dissolving reagent grade chemical powders in ultra-pure water. Spherical inclusions (up to 40 µm) were synthesized from the starting solutions in pre-cracked, HF-treated synthetic quartz crystals which were placed in gold capsules and equilibrated at 600°C, 100/200 MPa in cold seal pressure vessels. Fluid inclusion LA-ICP-MS analysis (University of Helsinki) yielded average I concentrations in excellent agreement with the starting solutions (27.3 µg/g ± 14 %RSD for the 27 µg/g solution and 77.6 µg/g ± 8.3 %RSD for the 78 µg/g solution). Average Br and I concentrations deviate less than 10 % from solution concentration values. For the low I concentration solutions, the synthetic inclusions were too small to detect I. Thus, given suitable standard materials and sufficient

Dissolution of nonmetallic inclusions at high-temperature heating

International Nuclear Information System (INIS)

Gubenko, S.I.

1983-01-01

The effect of high-temperature a nnealing on size, distribution and general content of non-metallic inclusions in steels is investigated. It is shown that high-temperature annealing of steel permits to reduce total amount of inclusions, their average size, as well as to control their composition and distribution in steel matrix. Partial or complete dissolution of inclusions takes place in respect to the type of non-metallic inclusions, temperature of annealing and holding duration. Cooling rate affects the investigated parameters. Under quenching the total amount of inclusions in steel is lower and average size of inclusions is larger than those under slow cooling. It is explained by precipitation of disperses ''satellites around the initial inclusions under low cooling. Composition of the satellites slightly differs from that of a ''mother's'' one. Change in composition of inclusions and creation of conditions for transition of unstable inclusions to a more stable state promotes change in properties of non-metallic inclusions that affects steel properties

Inclusive research and inclusive education: why connecting them makes sense for teachers’ and learners’ democratic development of education

OpenAIRE

Nind, Melanie

2014-01-01

Following pushes from the disability movement(s) and increased interest in children and young people becoming involved in research concerning them, inclusive research is growing within and beyond education establishments. Yet this arena is alive with interesting and largely unanswered questions. This paper discusses some of them: What do inclusive research and inclusive education have in common? Where have the moves towards inclusive (participatory and emancipatory) research happened and why?...

Towards inclusive occupational therapy: Introducing the CORE approach for inclusive and occupation-focused practice.

Science.gov (United States)

Pereira, Robert B

2017-12-01

Occupation is a human right and a social determinant of health. It is also taken for granted. Having access to, and participating in, occupation, is intricately linked to positive health and wellbeing. Despite theory and evidence to support the link between occupation, health and wellbeing, occupational therapists can struggle with applying an occupation focus in practice and knowing how to use occupational frameworks to enable occupation. The purpose of this paper is to introduce the Capabilities, Opportunities, Resources and Environments (CORE) approach for inclusive and occupation-focused practice. It provides occupational therapists with a means of operationalising occupational enablement and facilitating social inclusion. The CORE approach is introduced by linking its main ideas to Economist and Nobel Prize Laureate Amartya Sen's capabilities approach, as well as findings from the author's doctoral research into entrenched disadvantage and social inclusion. Practical questions guided by the CORE approach's acronym are given to explore how the approach can be utilised alongside other occupational models and frameworks to encourage strategies for effective enablement through occupation for social inclusion. As experts in enabling occupation, occupational therapists can use the CORE approach to design occupation-focused interventions and promote inclusive occupational therapy. © 2017 Occupational Therapy Australia.

The depth of sub-lithospheric diamond formation and the redistribution of carbon in the deep mantle

Science.gov (United States)

Beyer, Christopher; Frost, Daniel J.

2017-03-01

Most diamonds form in the Earth's lithosphere but a small proportion contain Si-rich majoritic garnet inclusions that indicate formation in the deeper mantle. The compositions of syngenetic garnet inclusions can potential yield information on both the depth and mantle lithology in which the diamonds formed. Pressure dependent changes in garnet compositions have been calibrated using the results of experiments conducted in a multi-anvil apparatus at pressures between 6 and 16 GPa and temperatures of 1000 to 1400 °C. Using the results of these experiments a barometer was formulated based on an empirical parameterisation of the two major majoritic substitutions, referred to as majorite (Maj; Al3+ =Mg2+ +Si4+), and Na-majorite (Na-Maj; Mg2+ +Al3+ =Na+ +Si4+). Moreover, previously published experimental garnet compositions from basaltic, kimberlite, komatiite and peridotite bulk compositions were included in the calibration, which consequently covers pressures from 6 to 20 GPa and temperatures from 900 to 2100 °C. Experimental pressures are reproduced over these conditions with a standard deviation of 0.86 GPa. The barometer is used to determine equilibration pressures of approximately 500 reported garnet inclusions in diamonds from a range of localities. As the majority of these inclusions are proposed to be syngenetic this allows a detailed picture of diamond formation depths and associated source rocks to be established using inclusion chemistry. Geographic differences in diamond source rocks are mapped within the sub-lithospheric mantle to over 500 km depth. Continuous diamond formation occurs over this depth range within lithologies with eclogitic affinities but also in lithologies that appear transitional between eclogitic and peridotitic bulk compositions, with an affinity to pyroxenites. The geographic differences between eclogitic and pyroxenitic diamond source rocks are rationalised in terms of diamond formation within downwelling and upwelling regimes

TOWARDS AN INCLUSIVE SCHOOL

Directory of Open Access Journals (Sweden)

Lucía López Menéndez

2015-06-01

Full Text Available Nowadays schools have to direct all efforts towards the comprehensive development of all students whatever their individual characteristics and their environment; they have to give a quality educational attention a qualified educational attention to the diversity in all their schools. This article presents an approach on the possibilities of developing a self-assessment using the Guide: "Index for Inclusion": “Index for Inclusion” published in the United kingdom by Centre for Studies on Inclusive Education (CSIE Tony Booth - Mel Ainscow (2002. This guide is a simple tool intended for schools to evaluate their reality in relation to important aspects of school organization and teaching-learning from the perspective of inclusion. From this self-assessment they can design specific programs to guide their educacional practice.

Axonal inclusions in the crab Hemigrapsus nudus.

Science.gov (United States)

Smith, R S

1978-10-01

Light microscopic examination of living giant axons from the walking legs of Hemigrapsus nudus revealed intra-axonal inclusions which were usually several tens of micrometers long and about 5 micron wide. The inclusions were filled with small light-scattering particles. The inclusions were shown, by thin section electron microscopy, to be composed largely 68% by volume) of mitochondria. Each inclusion was surrounded by membrane bounded spaces which are presumed to represent a part of the smooth endoplasmic reticulum. Similar inclusions were not found in the leg axons of a variety of other decapod crustaceans.

Teachers’ Perceptions of Inclusion in a Pilot Inclusive Education Program: Implications for Instructional Leadership

Directory of Open Access Journals (Sweden)

Zachary Y. Mngo

2018-01-01

Full Text Available The opinions of general education secondary school teachers in seven select schools involved in a pilot inclusive education program in the Northwest Region of Cameroon were sought. The findings reveal that most teachers in Cameroon still prefer separate special education institutions to inclusive ones. These conclusions contradict earlier research which showed that resistance to integrated classrooms was emanating from beliefs and customs. Teachers with some training on teaching students with disabilities and more experienced and highly educated teachers were more supportive of inclusive education indicating that resistance to the practice is linked to inadequate or complete lack of teachers’ preparedness. Younger, less experienced teachers with no training in special education indicated less enthusiasm regarding the benefits of inclusion, their ability to manage integrated classrooms, and teach students with disabilities. The implication of these findings for future research, institutional support systems, institutional policies, and overall instructional leadership is discussed in this article.

Paleoescatology in the sopas formation (Upper Pleistocene) form Uruguay, paleobilogic focus

International Nuclear Information System (INIS)

Verde, M.; Ubilla, M.; Soloviy, J.

1998-01-01

Continental tetrapod coprolites are reported for the first time for Uruguay, these remains come from the Sopas Formation (Upper Pleistocene). They are assigned to carnivore mammals based on morphology and inclusions of micrommmal remains besides of other attributes.(author)

Social inclusion and mental health.

Science.gov (United States)

Cobigo, Virginie; Stuart, Heather

2010-09-01

Recent research on approaches to improving social inclusion for people with mental disabilities is reviewed. We describe four approaches (or tools) that can be used to improve social inclusion for people with mental disabilities: legislation, community-based supports and services, antistigma/antidiscrimination initiatives, and system monitoring and evaluation. While legislative solutions are the most prevalent, and provide an important framework to support social inclusion, research shows that their full implementation remains problematic. Community-based supports and services that are person-centered and recovery-oriented hold considerable promise, but they are not widely available nor have they been widely evaluated. Antistigma and antidiscrimination strategies are gaining in popularity and offer important avenues for eliminating social barriers and promoting adequate and equitable access to care. Finally, in the context of the current human rights and evidence-based health paradigms, systematic evidence will be needed to support efforts to promote social inclusion for people with mental disabilities, highlight social inequities, and develop best practice approaches. Tools that promote social inclusion of persons with mental disabilities are available, though not yet implemented in a way to fully realize the goals of current disability discourse.

Translating Inclusion

DEFF Research Database (Denmark)

Fallov, Mia Arp; Birk, Rasmus

2018-01-01

The purpose of this paper is to explore how practices of translation shape particular paths of inclusion for people living in marginalized residential areas in Denmark. Inclusion, we argue, is not an end-state, but rather something which must be constantly performed. Active citizenship, today......, is not merely a question of participation, but of learning to become active in all spheres of life. The paper draws on empirical examples from a multi-sited field work in 6 different sites of local community work in Denmark, to demonstrate how different dimensions of translation are involved in shaping active...... citizenship. We propose the following different dimensions of translation: translating authority, translating language, translating social problems. The paper takes its theoretical point of departure from assemblage urbanism, arguing that cities are heterogeneous assemblages of socio-material interactions...

Advantages of inclusive diversity treatment: perspective of the principal agents responsible for its development

Directory of Open Access Journals (Sweden)

Raúl GONZÁLEZ FERNÁNDEZ

2016-12-01

Full Text Available Recent studies have suggested an initially favorable teacher attitude towards inclusive diversity treatment, with these teachers being the true authors of its development, while at the same time, the numerous advantages of educational inclusion are apparent for both students and the educational system itself. Therefore, using a mixed methodology that combines the search and analysis of quantitative and qualitative data, a study was conducted in order to determine the perception of Early Childhood, Primary and Secondary school teachers regarding the advantages and positive effects of educational inclusion, while at the same time verifying whether or not significant differences exist based on educational stage and years of teaching experience. The data obtained via a questionnaire and interview designed for these purposes reveals that teachers find inclusive diversity treatment to have multiple advantages: for students with special needs, particularly in the area of affective, emotional and social development; for students without special needs, contributing to the development and optimal formation of their ethical and moral values; and, finally, for the functioning of the educational institution itself, mainly in the area of pedagogical renewal and teacher updating. However, significant differences were revealed in this perception based on the educational stage taught by the teachers, and to a lesser degree, based on their years of teaching experience.

Aluminum deoxidation equilibria and inclusion modification mechanism by calcium treatment of stainless steel melts

International Nuclear Information System (INIS)

Park, Joo Hyun; Kim, Dong Sik; Kim, Yong Hwan; Lee, Sang Beom

2005-01-01

A thermodynamic equilibrium between aluminum and oxygen along with the inclusion morphology in Fe-16%Cr stainless steel was investigated to understand the fundamentals of aluminum deoxidation technology for ferritic stainless steels. Further, the effects of calcium addition on the changes in chemistry and morphology of inclusions were discussed. The measured results for aluminum-oxygen equilibria exhibit relatively good agreement with the calculated values, indicating that the introduction of the first- and second-order interaction parameters, recently reported, is reasonable to numerically express aluminum deoxidation equilibrium in a ferritic stainless steel. In the composition of dissolved aluminum content greater than about 60 ppm, pure alumina particles were observed, while the alumino-manganese silicates containing Cr 2 O 3 were appeared at less than 20 mass ppm of dissolved aluminum. The formation of calcium aluminate inclusions after Ca treatment could be discussed based on the thermodynamic equilibrium with calcium, aluminum, and oxygen in the steel melts. In the composition of steel melt with relatively high content of calcium and low aluminum, the log(X CaO /X Al 2 O 3 ) of inclusions linearly increases with increasing the log [a Ca /a Al 2 ·a O 2 ] with the slope close to unity. However, the slope of the line is significantly lower than the expected value in the composition of steel melt with relatively low calcium and high aluminum contents

On the hadron formation time in pion-nucleus interaction

International Nuclear Information System (INIS)

Bravina, L.V.; Korotkikh, V.L.; Sarycheva, L.I.; Sivoklokov, S.Yu.

1992-01-01

Differences in the observable characteristics of pion-nucleus interactions at high energy are investigated for two definitions of the hadron formation time. The Monte Carlo simulation of hadron-nucleus interactions and quark-gluon string model for hadron-hadron collisions are used. It is shown that the momentum spectrum of the protons in the target fragmentation region is most sensitive to the definition of the formation time. The inclusive meson and meson resonance spectra are similar in the both versions. 20 refs.; 4 figs.; 1 tab

Suddenly included: cultural differences in experiencing re-inclusion.

Science.gov (United States)

Pfundmair, Michaela; Graupmann, Verena; Du, Hongfei; Frey, Dieter; Aydin, Nilüfer

2015-03-01

In the current research, we examined whether re-inclusion (i.e. the change from a previous state of exclusion to a new state of inclusion) was perceived differently by people with individualistic and collectivistic cultural backgrounds. Individualists (German and Austrian participants) but not collectivists (Chinese participants) experienced re-inclusion differently than continued inclusion: While collectivistic participants did not differentiate between both kinds of inclusion, individualistic participants showed reduced fulfilment of their psychological needs under re-inclusion compared to continued inclusion. The results moreover revealed that only participants from individualistic cultures expressed more feelings of exclusion when re-included than when continually included. These exclusionary feelings partially mediated the relationship between the different states of inclusion and basic need fulfilment. © 2014 International Union of Psychological Science.

Analysis of hopanes and steranes in single oil-bearing fluid inclusions using time-of-flight secondary ion mass spectrometry (ToF-SIMS).

Science.gov (United States)

Siljeström, S; Lausmaa, J; Sjövall, P; Broman, C; Thiel, V; Hode, T

2010-01-01

Steranes and hopanes are organic biomarkers used as indicators for the first appearance of eukaryotes and cyanobacteria on Earth. Oil-bearing fluid inclusions may provide a contamination-free source of Precambrian biomarkers, as the oil has been secluded from the environment since the formation of the inclusion. However, analysis of biomarkers in single oil-bearing fluid inclusions, which is often necessary due to the presence of different generations of inclusions, has not been possible due to the small size of most inclusions. Here, we have used time-of-flight secondary ion mass spectrometry (ToF-SIMS) to monitor in real time the opening of individual inclusions trapped in hydrothermal veins of fluorite and calcite and containing oil from Ordovician source rocks. Opening of the inclusions was performed by using a focused C(60)(+) ion beam and the in situ content was precisely analysed for C(27)-C(29) steranes and C(29)-C(32) hopanes using Bi(3)(+) as primary ions. The capacity to unambiguously detect these biomarkers in the picoliter amount of crude oil from a single, normal-sized (15-30 mum in diameter) inclusion makes the approach promising in the search of organic biomarkers for life's early evolution on Earth.

Numerical Simulations of Inclusion Behavior in Gas-Stirred Ladles

Science.gov (United States)

Lou, Wentao; Zhu, Miaoyong

2013-06-01

A computation fluid dynamics-population balance model (CFD-PBM) coupled model has been proposed to investigate the bubbly plume flow and inclusion behavior including growth, size distribution, and removal in gas-stirred ladles, and some new and important phenomena and mechanisms were presented. For the bubbly plume flow, a modified k- ɛ model with extra source terms to account for the bubble-induced turbulence was adopted to model the turbulence, and the bubble turbulent dispersion force was taken into account to predict gas volume fraction distribution in the turbulent gas-stirred system. For inclusion behavior, the phenomena of inclusions turbulent random motion, bubbles wake, and slag eye forming on the molten steel surface were considered. In addition, the multiple mechanisms both that promote inclusion growth due to inclusion-inclusion collision caused by turbulent random motion, shear rate in turbulent eddy, and difference inclusion Stokes velocities, and the mechanisms that promote inclusion removal due to bubble-inclusion turbulence random collision, bubble-inclusion turbulent shear collision, bubble-inclusion buoyancy collision, inclusion own floatation near slag-metal interface, bubble wake capture, and wall adhesion were investigated. The importance of different mechanisms and total inclusion removal ratio under different conditions, and the distribution of inclusion number densities in ladle, were discussed and clarified. The results show that at a low gas flow rate, the inclusion growth is mainly attributed to both turbulent shear collision and Stokes collision, which is notably affected by the Stokes collision efficiency, and the inclusion removal is mainly attributed to the bubble-inclusion buoyancy collision and inclusion own floatation near slag-metal interface. At a higher gas flow rate, the inclusions appear as turbulence random motion in bubbly plume zone, and both the inclusion-inclusion and inclusion-bubble turbulent random collisions become

Empirical, thermodynamic and quantum-chemical investigations of inclusion complexation between flavanones and (2-hydroxypropyl)-cyclodextrins.

Science.gov (United States)

Liu, Benguo; Li, Wei; Nguyen, Tien An; Zhao, Jian

2012-09-15

The inclusion complexation of (2-hydroxypropyl)-cyclodextrins with flavanones was investigated by phase solubility measurements, as well as thermodynamic and quantum chemical methods. Inclusion complexes were formed between (2-hydroxypropyl)-α-cyclodextrin (HP-α-CD), (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD), (2-hydroxypropyl)-γ-cyclodextrin (HP-γ-CD) and β-cyclodextrin (β-CD) and four flavanones (naringenin, naringin, hesperetin and dihydromyricetin) in aqueous solutions and their phase solubility was determined. For all the flavanones, the stability constants of their complexes formed with different CDs followed the rank order: HP-β-CD (MW 1540)>HP-β-CD (MW 1460)>HP-β-CD (MW 1380)>β-CD>HP-γ-CD>HP-α-CD. Experimental results and quantum chemical calculations showed that the ability of flavanones to form inclusion complex with (2-hydroxypropyl)-cyclodextrins was determined by both the steric effect and hydrophobicity of the flavanones. For flavanones that have similar molecular volumes, the hydrophobicity of the molecule was the main determining factor of its ability to form inclusion complexes with HP-β-CD, and the hydrophobicity parameter Log P is highly correlated with the stability constant of the complexes. Results of thermodynamic study demonstrated that hydrophobic interaction is the main driving force for the formation process of the flavanone-CD inclusion complexes. Quantum chemical analysis of the most active hydroxyl groups and HOMO (the highest occupied molecular orbital) showed that the B ring of the flavanones was most likely involved in hydrogen bonding with the side groups in the cavity of the CDs, through which the inclusion complex was stabilised. Copyright © 2012 Elsevier Ltd. All rights reserved.

The semi-inclusive jet function in SCET and small radius resummation for inclusive jet production

International Nuclear Information System (INIS)

Kang, Zhong-Bo; Ringer, Felix; Vitev, Ivan

2016-01-01

We introduce a new kind of jet function: the semi-inclusive jet function J_i(z,ω_J,μ), which describes how a parton i is transformed into a jet with a jet radius R and energy fraction z=ω_J/ω, with ω_J and ω being the large light-cone momentum component of the jet and the corresponding parton i that initiates the jet, respectively. Within the framework of Soft Collinear Effective Theory (SCET) we calculate both J_q(z,ω_J,μ) and J_g(z,ω_J,μ) to the next-to-leading order (NLO) for cone and anti-k_T algorithms. We demonstrate that the renormalization group (RG) equations for J_i(z,ω_J,μ) follow exactly the usual DGLAP evolution, which can be used to perform the ln R resummation for inclusive jet cross sections with a small jet radius R. We clarify the difference between our RG equations for J_i(z,ω_J,μ) and those for the so-called unmeasured jet functions J_i(ω_J,μ), widely used in SCET for exclusive jet production. Finally, we present applications of the new semi-inclusive jet functions to inclusive jet production in e"+e"− and pp collisions. We demonstrate that single inclusive jet production in these collisions shares the same short-distance hard functions as single inclusive hadron production, with only the fragmentation functions D_i"h(z,μ) replaced by J_i(z,ω_J,μ). This can facilitate more efficient higher-order analytical computations of jet cross sections. We further match our ln R resummation at both LL_R and NLL_R to fixed NLO results and present the phenomenological implications for single inclusive jet production at the LHC.

Study in aqueous solution of the praseodymium inclusion in β-cyclodextrin in 2 M of NaCl

International Nuclear Information System (INIS)

De la Cruz M, N.

2013-01-01

In the fission of uranium to produce electricity, generated between the fission products which are the lanthanides and actinides that at any given time may come into contact with aqueous media, because of this, praseodymium was including in the β-cyclodextrin in order to increase the solubility and stability of praseodymium by forming inclusion complexes Praseodymium-β-cyclodextrin (Pr-β-Cd). The inclusion study was conducted in a proportion of praseodymium and β-cyclodextrin. Infrared spectra, Raman and X-ray diffraction showed the presence of praseodymium and β-cyclodextrin in the inclusion complex, in both proportions. The analysis by scanning electron microscopy confirmed the inclusion of praseodymium in βcyclodextrin. In general, the results of characterization obtained by these techniques show the formation of the inclusion complex. Furthermore, the behaviour of praseodymium inclusion in the β-cyclodextrin was studied in 2 M NaCl at 303 K and free-CO 2 conditions. For this reason, we used two methods: spectrophotometric and potentiometric titration direct of praseodymium-β-cyclodextrin, the data were treated graphically and with the program SUPERQUAD, respectively. The values obtained for praseodymium by spectrophotometric method was: log β 1 = -8.75 calculated graphically and with the potentiometric method, using program SUPERQUAD were logβ 1,OH = -8.73 ± 0.01 logβ 1,2OH = -18.27 ± 0.16 and logβ 1,3OH = -26.44 ± 0.02 obtained simultaneously. (Author)

Beliefs in social inclusion: Invariance in associations among hope, dysfunctional attitudes, and social inclusion across adolescence and young adulthood.

Science.gov (United States)

Berry, Clio; Greenwood, Kathryn

2017-09-19

Social disability in youth is an important precursor of long-term social and mental health problems. Social inclusion is a key policy driver and fits well within a new paradigm of health and well-being rather than illness-oriented services, yet little is known about social inclusion and its facilitators for "healthy" young people. We present a novel exploratory structural analysis of social inclusion using measures from 387 14- to 36-year-olds. Our model represents social inclusion as comprising social activity and community belonging, with both domains predicted by hopeful and dysfunctional self-beliefs but hopefulness more uniquely predicting social inclusion in adolescence. We conclude that social inclusion can be modeled for meaningful comparison across spectra of development, mental health, and functioning.

Indonesian teachers' epistemological beliefs and inclusive education.

Science.gov (United States)

Sheehy, Kieron; Budiyanto; Kaye, Helen; Rofiah, Khofidotur

2017-01-01

A growing number of children with intellectual disabilities attend inclusive schools in Indonesia. Previous research has suggested that teachers' type of school and experience influences their beliefs about inclusive education. This research collected questionnaire data from 267 Indonesian teachers and compared the responses from those working in inclusive, special and regular schools regarding their epistemological and pedagogical beliefs. The results showed that teachers in inclusive schools expressed stronger social constructivist beliefs than those in other schools. However, it was teachers' epistemological beliefs, rather than their type of school or experience, which were the significant predictor of their beliefs about inclusive education. The findings suggest that international epistemological research needs to have a more nuanced view of constructivist models of learning to better understand and inform how inclusive pedagogy is being enacted in different contexts.

The Inclusive Classroom. Professional's Guide.

Science.gov (United States)

Grenot-Scheyer, Marquita; And Others

Inclusive education reflects the changing culture of contemporary schools with emphasis on active learning, authentic assessment practices, applied curriculum, multi-level instructional approaches, and increased attention to diverse student needs and individualization. This guide is intended to help teachers implement inclusive educational…

Teacher preparedness for inclusive education

African Journals Online (AJOL)

lynette

Department of Information Systems, Faculty of Economic & Management ... paredness of teachers for this new policy of inclusion. ... of inclusive classrooms, if viewed in global perspective (Dyson & .... teachers experience stress when including learners with special needs. ..... Stress areas and coping skills of South African.

Invasion of Hydrous Fluids Predates Kimberlite Formation

Science.gov (United States)

Kopylova, M. G.; Wang, Q.; Smith, E. M.

2017-12-01

Petrological observations on diamonds and peridotite xenoliths in kimberlites point towards an influx of hydrous metasomatic fluids shortly predating kimberlite formation. Diamonds may grow at different times within the same segment of the cratonic mantle, and diamonds that form shortly before (diamonds typically contain 10-25 wt.% water in fluid inclusions, while older octahedrally-grown diamonds host "dry" N2-CO2 fluids. Our recent studies of fluids in diamond now show that many different kinds of diamonds can contain fluid inclusions. Specifically, we found a new way to observe and analyze fluids in octahedrally-grown, non-fibrous diamonds by examining healed fractures. This is a new textural context for fluid inclusions that reveals a valuable physical record of infiltrating mantle fluids, that postdate diamond growth, but equilibrate within the diamond stability field at depths beyond 150 km. Another sign of the aqueous fluids influx is the formation of distinct peridotite textures shortly predating the kimberlite. Kimberlites entrain peridotite xenoliths with several types of textures: older coarse metamorphic textures and younger, sheared textures. The preserved contrast in grain sizes between porphyroclasts and neoblasts in sheared peridotites constrain the maximum duration of annealing. Experimental estimates of the annealing time vary from 7x107 sec (2 years) to 106 years (1 My) depending on olivine hydration, strain rate, pressure, temperature and, ultimately, the annealing mechanism. Kimberlite sampling of sheared peridotites from the lithosphere- asthenosphere boundary (LAB) implies their formation no earlier than 1 My prior to the kimberlite ascent. Water contents of olivine measured by FTIR spectrometry using polarized light demonstrated contrasting hydration of coarse and sheared samples. Olivine from sheared peridotite samples has the average water content of 78±3 ppm, in contrast to the less hydrated coarse peridotites (33±6 ppm). LAB hydration

Inclusive fitness maximization: An axiomatic approach.

Science.gov (United States)

Okasha, Samir; Weymark, John A; Bossert, Walter

2014-06-07

Kin selection theorists argue that evolution in social contexts will lead organisms to behave as if maximizing their inclusive, as opposed to personal, fitness. The inclusive fitness concept allows biologists to treat organisms as akin to rational agents seeking to maximize a utility function. Here we develop this idea and place it on a firm footing by employing a standard decision-theoretic methodology. We show how the principle of inclusive fitness maximization and a related principle of quasi-inclusive fitness maximization can be derived from axioms on an individual׳s 'as if preferences' (binary choices) for the case in which phenotypic effects are additive. Our results help integrate evolutionary theory and rational choice theory, help draw out the behavioural implications of inclusive fitness maximization, and point to a possible way in which evolution could lead organisms to implement it. Copyright © 2014 Elsevier Ltd. All rights reserved.

Inclusão digital: sistema de engrenagens | Digital inclusion: systems of gears

Directory of Open Access Journals (Sweden)

Diana Cubillos

2009-04-01

Palavras-chave inclusão digital; economia política; política de informação Abstract The notion of digital inclusion, present in the scientific field as well as in social life, a way in field scientific, how much in the practical life, it has generated studies on the question however as combat the battling social inequality in the comprehension of mechanisms of differentiation between rich and poor, to understand the different mechanisms between rich and poor, however and served as an economic instrument based on the knowledge and technological advance progress. The results are relevant insofar as accomplishment of this reflection is excellent, a time that the technological advancement have has stimulated transformations in the local and global political economy and in the new world order: frantic and unquestioned consumption and without questioning. The digital inclusion is here compared to a system of gears. These parts that if they interconnect for the functioning of a system are seen here in this context here treat, as information policies inserted of in the criminal public actions. These actions establish a connection with the tools of information and communication technologies (TICs that in their turn it is are connected with the social actors, who, for diverse reasons, find themselves excluded from of chances opportunities, goods and hopes for the future visions. Keywords digital inclusion; political economy; informational policies

Building Inclusion from the Ground up: A Review of Whole School Re-Culturing Programmes for Sustaining Inclusive Change

Science.gov (United States)

McMaster, Christopher

2013-01-01

This paper suggests that whole school re-culturing programmes can potentially assist in the creation of more inclusive value orientated schools. The relationship between school culture and successful inclusion has been demonstrated in the literature. Furthermore, the structure of whole school programmes in inculcating inclusive values and…

The problems of Russian inclusive education

Directory of Open Access Journals (Sweden)

Kurmyshova O.A.

2017-02-01

Full Text Available the article is devoted to problems of Russian inclusive education. Based on the results of theoretical analysis the author raises some questions and their solutions may help to increase the effectiveness of the activity of inclusive educational organizations, provide harmonization of relations of inclusive education members and that will guarantee a successful integration of children with disabilities and special needs in the society.

Measuring Attitudes toward Inclusive Education.

Science.gov (United States)

Wilczenski, Felicia L.

1992-01-01

Developed scale to measure attitudes toward inclusive education, in which disabled students are responsibility of regular teacher supported by specialists. Administered scale to 301 elementary and secondary teachers and to 144 undergraduate elementary education majors. Analysis yielded four discrete dimensions of inclusive education with…

Social Inclusion and Local Practices of Belonging

Directory of Open Access Journals (Sweden)

Rob Garbutt

2009-09-01

Full Text Available Social inclusion has been conceptualised as having two key aspects: distributional aspects relating to access to resources including employment, and relational aspects which concern the connections between people and the wider society. While both are important, the emphasis in Australian social inclusion policy has been on distributional aspects. This paper focuses on the relational aspects of social inclusion, and argues that it is critically important to include relational considerations in social inclusion policy. Central to the relational aspects of social inclusion is achieving a sense of belonging, particularly at the everyday, local level. Belonging in this everyday sense can be thought of as an ongoing project achieved through everyday practices, rather than solely in terms of membership of a group. While many such practices, for example regularly engaging in team sports, are accepted ways of establishing and maintaining belonging, for others in a community practices of belonging may necessitate disrupting or at least broadening the established norms of how one belongs. To ground this discussion of inclusion and belonging, this paper draws on practices of belonging in a regional community. Established norms of belonging are examined through the idea of ‘being a local’, a way of belonging that appears to be based on membership. The paper then turns to two local projects which disrupt the exclusive bounds of local membership and establish new and inclusive practices of belonging. To conclude, parallels are drawn between the boundaries which define ‘the social’ in social inclusion and ‘the local community’ in being a local, to argue for the importance of including relational aspects of social inclusion within social inclusion policy debates and program formulation.

Nuclear Glycogen Inclusions in Canine Parietal Cells.

Science.gov (United States)

Silvestri, S; Lepri, E; Dall'Aglio, C; Marchesi, M C; Vitellozzi, G

2017-05-01

Nuclear glycogen inclusions occur infrequently in pathologic conditions but also in normal human and animal tissues. Their function or significance is unclear. To the best of the authors' knowledge, no reports of nuclear glycogen inclusions in canine parietal cells exist. After initial observations of nuclear inclusions/pseudoinclusions during routine histopathology, the authors retrospectively examined samples of gastric mucosa from dogs presenting with gastrointestinal signs for the presence of intranuclear inclusions/pseudoinclusions and determined their composition using histologic and electron-microscopic methods. In 24 of 108 cases (22%), the authors observed various numbers of intranuclear inclusions/pseudoinclusions within scattered parietal cells. Nuclei were characterized by marked karyomegaly and chromatin margination around a central optically empty or slightly eosinophilic area. The intranuclear inclusions/pseudoinclusions stained positive with periodic acid-Schiff (PAS) and were diastase sensitive, consistent with glycogen. Several PAS-positive/diastase-sensitive sections were further examined by transmission electron microscopy, also using periodic acid-thiocarbohydrazide-silver proteinate (PA-TCH-SP) staining to identify polysaccharides. Ultrastructurally, the nuclear inclusions were composed of electron-dense particles that were not membrane bound, without evidence of nuclear membrane invaginations or cytoplasmic organelles in the nuclei, and positive staining with PA-TCH-SP, confirming a glycogen composition. No cytoplasmic glycogen deposits were observed, suggesting that the intranuclear glycogen inclusions were probably synthesized in loco. Nuclear glycogen inclusions were not associated with gastritis or colonization by Helicobacter-like organisms ( P > .05). Our findings suggest that nuclear glycogen inclusions in canine parietal cells could be an incidental finding. Nevertheless, since nuclear glycogen is present in several pathologic

Employment of colorimetric enzyme assay for monitoring expression and solubility of GST fusion proteins targeted to inclusion bodies.

Science.gov (United States)

Mačinković, Igor S; Abughren, Mohamed; Mrkic, Ivan; Grozdanović, Milica M; Prodanović, Radivoje; Gavrović-Jankulović, Marija

2013-12-01

High levels of recombinant protein expression can lead to the formation of insoluble inclusion bodies. These complex aggregates are commonly solubilized in strong denaturants, such as 6-8M urea, although, if possible, solubilization under milder conditions could facilitate subsequent refolding and purification of bioactive proteins. Commercially available GST-tag assays are designed for quantitative measurement of GST activity under native conditions. GST fusion proteins accumulated in inclusion bodies are considered to be undetectable by such assays. In this work, solubilization of recombinantly produced proteins was performed in 4M urea. The activity of rGST was assayed in 2M urea and it was shown that rGST preserves 85% of its activity under such denaturing conditions. A colorimetric GST activity assay with 1-chloro-2, 4-dinitrobenzene (CDNB) was examined for use in rapid detection of expression targeted to inclusion bodies and for the identification of inclusion body proteins which can be solubilized in low concentrations of chaotropic agents. Applicability of the assay was evaluated by tracking protein expression of two GST-fused allergens of biopharmaceutical value in E. coli, GST-Der p 2 and GST-Mus a 5, both targeted to inclusion bodies. Copyright © 2013 Elsevier B.V. All rights reserved.

NMR spectroscopic characterization of β-cyclodextrin inclusion complex with vanillin

International Nuclear Information System (INIS)

Pirnau, Adrian; Bogdan, Mircea; Floare, Calin G

2009-01-01

The inclusion of vanillin by β-cyclodextrin was investigated by 1 H NMR. The continuous variation technique was used to evidence the formation of soluble 1:1 complex in aqueous solution. The association constant of vanillin with β-cyclodextrin has been obtained at 298 K by fitting the experimental chemical shifts differences, Δδ obs δ free - δ obs of the observed guest and host protons, with a non-linear regression method. Besides the effective association constant, the fitting procedure allows a precise determination of all chemical shift parameters characterizing the pure complex. They can by used for an analysis of the geometry of the molecular complex in solution.

Inclusive Discourse? Local Media Coverage of the Terri Schiavo Case.

Science.gov (United States)

Rohlinger, Deana A; Pederson, JoEllen; Valle, Giuseppina

2015-01-01

This article contributes to a more systematic understanding of the role of mainstream media in deliberative processes by analyzing how inclusive local newspapers are of diverse perspectives on the Terri Schiavo case. Using both Pearson's chi-square test and multinomial logistic regression, we assess how ownership, state political ideology, geographic location, and news format affect what ideas are included in the debate over whether Terri Schiavo's hydration and nutrition tubes should be removed as well as the tone with which these ideas are discussed. We find that mainstream newspapers are relatively inclusive of diverse ideas and perspectives-regardless of whether the newspaper is independently or corporately owned, the political leanings of the target audience, and the geographic location of the outlet. However, we also find that local newspapers do significantly differ from one another in terms of the frequency and tone with which they include diverse viewpoints. Our research suggests that local outlets downplay ideas that are likely to be regarded as controversial by their target audiences. We conclude with a discussion of the implications of this research for understanding the role of media in deliberative democratic processes in the United States.

Membrane and inclusion body targeting of lyssavirus matrix proteins.

Science.gov (United States)

Pollin, Reiko; Granzow, Harald; Köllner, Bernd; Conzelmann, Karl-Klaus; Finke, Stefan

2013-02-01

Lyssavirus matrix proteins (M) support virus budding and have accessory functions that may contribute to host cell manipulation and adaptation to specific hosts. Here, we show that rabies virus (RABV) and European Bat Lyssavirus Type 1 (EBLV-1) M proteins differ in targeting and accumulation at cellular membranes. In contrast to RABV M, EBLV-1 M expressed from authentic EBLV-1 or chimeric RABV accumulated at the Golgi apparatus. Chimeric M proteins revealed that Golgi association depends on the integrity of the entire EBLV-1 M protein. Since RABV and EBLV-1 M differ in the use of cellular membranes for particle formation, differential membrane targeting and transport of M might determine the site of virus production. Moreover, both RABV and EBLV-1 M were for the first time detected within the nucleus and in Negri body-like inclusions bodies. Whereas nuclear M may imply hitherto unknown functions of lyssavirus M in host cell manipulation, the presence of M in inclusion bodies may correlate with regulatory functions of M in virus RNA synthesis. The data strongly support a model in which targeting of lyssavirus M proteins to distinctintracellular sites is a key determinant of diverse features in lyssavirus replication, host adaptation and pathogenesis. © 2012 Blackwell Publishing Ltd.

Multilingualism and Social Inclusion

DEFF Research Database (Denmark)

2017-01-01

This is a thematic issue on the relation between multilingualism and social inclusion. Due to globalization, Europeanization, supranational and transnational regulations linguistic diversity and multilingualism are on the rise. Migration and old and new forms of mobility play an important role...... in these processes. As a consequence, English as the only global language is spreading around the world, including Europe and the European Union. Social and linguistic inclusion was accounted for in the pre-globalization age by the nation-state ideology implementing the ‘one nation-one people-one language’ doctrine...... in governance and daily life protected by a legal framework. This does not mean that there is full equality of languages. This carries over to the fair and just social inclusion of the speakers of these weaker, dominated languages as well. There is always a power question related to multilingualism. The ten...

The Evolution of Secondary Inclusion.

Science.gov (United States)

Thousand, Jacqueline; Rosenberg, Richard L.; Bishop, Kathryn D.; Villa, Richard A.

1997-01-01

Offers an alternative "Circle of Courage" model of education, derived from Native American culture, for creating inclusive high schools that welcome, value, support, and facilitate the learning of adolescents with differing abilities. Best practices related to curriculum, instruction, assessment, and campus life for effective inclusion are…

Determination of Three-Dimensional Morphology and Inner Structure of Second-Phase Inclusions in Metals by Non-Aqueous Solution Electrolytic and Room Temperature Organic Methods

OpenAIRE

Jing Guo; Keming Fang; Hanjie Guo; Yiwa Luo; Shengchao Duan; Xiao Shi; Wensheng Yang

2018-01-01

The secondary-phase particles in metals, particularly those composed of non-metallic materials, are often detrimental to the mechanical properties of metals; thus, it is crucial to control inclusion formation and growth. One of the challenges is determining the three-dimensional morphology and inner structures of such inclusions. In this study, a non-aqueous solution electrolytic method and a room-temperature organic technique were developed based on the principle of electrochemistry to deter...

Examining inclusive practices in Nicaraguan schools

OpenAIRE

Delkamiller, Julie; Swain, Kristine; Leader-Janssen, Elizabeth M.; Ritzman, Mitzi J.

2013-01-01

Inkliuzinis praktikos nagrinėjimas Nikaragvos mokyklose. The purpose of this study was to examine Nicaraguan teachers’ efficacy for inclusive practices and current teaching practices in Nicaraguan schools as the first step in developing a special education training program. Sixty-one teachers in 15 schools completed the Teacher Efficacy of Inclusive Practice (TEIP) survey to determine their confidence in inclusive practices, collaboration and dealing with disruptive behaviors. Classroom ob...

Struggling for inclusive education in the North and the South: educators' perceptions on inclusive education in Finland and Zambia.

Science.gov (United States)

Moberg, Sakari; Savolainen, Hannu

2003-03-01

A survey assessed the perceptions of 1350 Zambian teachers and parents and 512 Finnish teachers regarding inclusive education and consequently the best placement for children with different disabilities. On the whole, perceptions varied but were quite critical. On inclusion in general, the regular (also termed "ordinary") Finnish teachers were the most critical group and the Finnish special education teachers the most optimistic. Most respondents felt that inclusive education enhances social justice. However, the pursuit of inclusion in practice, especially the guarantee of good and effective education for all, was seen as problematic. Compared with Finnish respondents, the Zambian respondents preferred a more segregated educational environment for children with different disabilities. Type and severity of disability affected the preferred educational setting and there were clear differences in this regard between the respondents from the two countries. The findings support the idea that educators' attitudes towards inclusion are important in developing inclusive school systems and that inclusive education is best understood as a multidimensional concept that, at the practical level, is highly context-dependent.

Palladium Catalyzed Allylic C-H Alkylation

DEFF Research Database (Denmark)

Engelin, Casper Junker; Fristrup, Peter

2011-01-01

are highlighted with emphasis on those leading to C-C bond formation, but where it was deemed necessary for the general understanding of the process closely related C-H oxidations and aminations are also included. It is found that C-H cleavage is most likely achieved by ligand participation which could involve......-H alkylation reaction which is the topic of the current review. Particular emphasis is put on current mechanistic proposals for the three reaction types comprising the overall transformation: C-H activation, nucleophillic addition, and re-oxidation of the active catalyst. Recent advances in C-H bond activation...... an acetate ion coordinated to Pd. Several of the reported systems rely on benzoquinone for re-oxidation of the active catalyst. The scope for nucleophilic addition in allylic C-H alkylation is currently limited, due to demands on pKa of the nucleophile. This limitation could be due to the pH dependence...

IDEA and Early Childhood Inclusion.

Science.gov (United States)

Smith, Barbara J.; Rapport, Mary Jane K.

This paper discusses 1997 amendments to the Individuals with Disabilities Education Act (IDEA) that promote the inclusion of children with disabilities in general early childhood education settings. The evolution of inclusion policy is explored and changes in disability terminology are described. Amended provisions are then explained and include:…

Early Childhood Inclusion in Turkey

Science.gov (United States)

Diken, Ibrahim H.; Rakap, Salih; Diken, Ozlem; Tomris, Gozde; Celik, Secil

2016-01-01

Inclusion of young children with disabilities into regular preschool classrooms is a common practice that has been implemented for several decades in industrialized nations around the world, and many developing countries including Turkey have been developing and implementing laws, regulation, and services to support inclusion and teaching in…

Re-framing Inclusive Education Through the Capability Approach: An Elaboration of the Model of Relational Inclusion

Directory of Open Access Journals (Sweden)

Maryam Dalkilic

2016-09-01

Full Text Available Scholars have called for the articulation of new frameworks in special education that are responsive to culture and context and that address the limitations of medical and social models of disability. In this article, we advance a theoretical and practical framework for inclusive education based on the integration of a model of relational inclusion with Amartya Sen’s (1985 Capability Approach. This integrated framework engages children, educators, and families in principled practices that acknowledge differences, rather than deficits, and enable attention to enhancing the capabilities of children with disabilities in inclusive educational environments. Implications include the development of policy that clarifies the process required to negotiate capabilities and valued functionings and the types of resources required to permit children, educators, and families to create relationally inclusive environments.

Inclusive Education in Georgia: Current Trends and Challenges

Science.gov (United States)

Tchintcharauli, Tinatin; Javakhishvili, Nino

2017-01-01

This article presents the first comprehensive study of the Georgian inclusive education system launched nationwide in 2006. An internationally recognised tool, the "Pathway to Inclusion--Barometer of Inclusive Education", was applied within the country to highlight the current position of inclusive education in Georgia. The collected…

Characteristics of Inclusive Faith Communities: A Preliminary Survey of Inclusive Practices in the United States

Science.gov (United States)

Griffin, Megan M.; Kane, Lydia W.; Taylor, Courtney; Francis, Susan H.; Hodapp, Robert M.

2012-01-01

Background: Although participation in faith communities is important to many individuals with disabilities, few studies have examined differences between communities that are more (versus less) inclusive. This study investigated characteristics of faith communities in the United States related to greater inclusion. Methods: Participants were 160…

Diffusion of nanosized sodium inclusions in platinum

International Nuclear Information System (INIS)

Poulsen, J.R.; Horsewell, A.; Eldrup, M.; Johnson, E.; Johansen, A.

1994-01-01

Na inclusions with diameters in the range from 2 nm to 15 nm have been made by ion implantation of Na into 70 nm thick single-crystalline Pt foils followed by annealing. The structure of solid inclusions and the diffusion of molten inclusions have been studied by transmission electron microscopy. At room temperature the inclusions are faceted and crystalline with a BCC structure and they are aligned topotactically with the Pt (FCC) matrix. The diffusion of inclusions in the liquid state was investigated by annealing at temperatures of 1227 K, 1432 K and 1534 K. The results are used to propose a method to produce sources for positron annihilation spectroscopy at high temperatures. (author)

Hydrogen embrittlement due to hydrogen-inclusion interactions

International Nuclear Information System (INIS)

Yu, H.Y.; Li, J.C.M.

1976-01-01

Plastic flow around inclusions creates elastic misfit which attracts hydrogen towards the regions of positive dilatation. Upon decohesion of the inclusion-matrix interface, the excess hydrogen escapes into the void and can produce sufficient pressure to cause void growth by plastic deformation. This mechanism of hydrogen embrittlement can be used to understand the increase of ductility with temperature, the decrease of ductility with hydrogen content, and the increase of ductility with the ultimate strength of the matrix. An examination of the effect of the shape of spheroid inclusion reveals that rods are more susceptible to hydrogen embrittlement than disks. The size of the inclusion is unimportant while the volume fraction of inclusions plays the usual role

Creating Inclusive Youth Programs for LGBTQ+ Communities

Directory of Open Access Journals (Sweden)

Katherine E. Soule

2017-06-01

Full Text Available It is vital for youth to experience inclusive programming that is welcoming. Extension has a responsibility and an obligation to provide youth with programs and spaces that are inclusive of all sexes, gender identities, gender expressions, and sexual orientations. This article provides an overview of appropriate terminology, as well as steps for creating inclusive Extension spaces and programs for youth who identify as members of lesbian, gay, bisexual, transgender, or queer/questioning (LGBTQ+ communities. With a focus on urban Extension audiences, this article uses accessible language, self-reflective prompts, and supporting visual aids to share lessons learned from ongoing inclusivity trainings with Extension personnel across the nation, as well as from research activities and inclusive programming.

The Inclusion of Music/the Music of Inclusion

Science.gov (United States)

Lubet, Alex

2009-01-01

The intention of this paper is to situate music within inclusive education. Intersections of music--widely regarded as a "talent" or hyperability--and disability provide unique perspectives on social organisation in general and human valuation in particular. Music is a ubiquitous and an essential component of learning beginning in infancy.…

Forging Inclusive Solutions: Experiential Earth Charter Education

Science.gov (United States)

Hill, Linda D.

2010-01-01

Forging Inclusive Solutions describes the aims, methodology and outcomes of Inclusive Leadership Adventures, an experiential education curriculum for exploring the Earth Charter. Experiential education builds meaningful relationships, skills, awareness and an inclusive community based on the Earth Charter principles. When we meet people where they…

Inclusion in Malaysian Integrated Preschools

Science.gov (United States)

Sukumaran, Sailajah; Loveridge, Judith; Green, Vanessa A.

2015-01-01

Inclusive education has been introduced through a number of policy developments in Malaysia over the last 10 years but there is little research investigating the extent and nature of inclusive education for preschoolers with special educational needs (SEN). This study surveyed both regular and special education teachers in Malaysian integrated…

Early Childhood Inclusion in Spain

Science.gov (United States)

Giné, Climent; Balcells-Balcells, Anna; Cañadas, Margarita; Paniagua, Gema

2016-01-01

This article describes early childhood inclusion in educational settings in Spain. First, we address the legislative framework of preschool education in Spain and offer a brief analysis of some relevant issues, including the current situation of early childhood education and inclusion at this stage. Second, current policies and practices relating…

Child wellness and social inclusion: values for action.

Science.gov (United States)

Prilleltensky, Isaac

2010-09-01

Participatory Action Research (PAR) with children and youth is at the intersection of child wellness and social inclusion. Exclusion and marginalization detract from personal and collective health. Inclusion, on the contrary, contributes to wellness. Hence, we should study inclusion and exclusion in the overall context of child wellness. This special issue offers a wealth of methodologies and lessons for fostering inclusion of young people through PAR. In an effort to synthesize my concerns with child wellness, inclusion, and the scholarly work of this special issue, this paper will (a) articulate the values underpinning the philosophy of social inclusion and child wellness, (b) suggest roles and responsibilities for putting these values into action, and (c) integrate the contributions of this special issue into the emerging framework for social inclusion and child wellness.

Epidermal Inclusion Cysts of The Breast

Directory of Open Access Journals (Sweden)

Amir R. Motabar

2009-02-01

Full Text Available Epidermal inclusion cysts are uncommon in the breast, but the consequences can besevere when these cysts occur in the breast parenchyma. Here,we report two suchcases. The patient in case 1 was an 37-year-old woman with a 3-cm palpable mass inthe right breast. Mammography revealed a round and smoothly outlined mass, whichindicated a benign tumor, and sonography showed an irregularly shaped and heterogeneoushypoechoic mass, fibroadenoma was suspected on the basis of clinical andimage findings, but excisional biopsy revealed an epidermal inclusion cyst. The patientin case 2 was a 50-year-old woman with a 2.5-cm lesion in the left breast. Mammographyrevealed a round, dense, smoothly outlined mass, and sonography showeda well-defined, central hyperechoic mass. . Breast cancer was suspected on the basisof the sonographic findings and the age of the patient, but the resected specimen revealedan epidermal inclusion cyst. Although epidermal inclusion cysts are benign,occasionally they may play a role in the origin of squamous carcinoma of the breast. .Mammographic and sonographic features of an epidermal cyst may mimic a malignantlesion. Malignant change appears to occur more frequently in epidermal inclusioncysts in the mammary gland, compared to common epidermal inclusion cysts,and this may be associated with origination of mammary epidermal inclusion cystsfrom squamous metaplasia of the mammary duct epithelium.Epidermmoid inclusion cyst of the breast is potentially serious, although such cystsare rare, and differentiation from a malignant or benign breast tumor is required. Excisionis probably the most appropriate treatment, and can eliminate the possible riskof malignant transformation.

Creating LGBTQ-Inclusive Care and Work Environments.

Science.gov (United States)

Jones-Schenk, Jan

2018-04-01

In considering the full depth of inclusion in care and work environments (and developing inclusive engagement skills for lesbian, gay, bisexual, transgender, queer or questioning [LGBTQ] patients and their families), professional development leaders must bring these discussions and shared learnings into the open. Understanding the LGBTQ population's unique needs is essential to providing personalized health care, and inclusive work environments help to foster more inclusive care for this population. J Contin Educ Nurs. 2018;49(4):151-153. Copyright 2018, SLACK Incorporated.

β-Cyclodextrin Inclusion Complex to Improve Physicochemical Properties of Pipemidic Acid: Characterization and Bioactivity Evaluation

Directory of Open Access Journals (Sweden)

Gaetano Malgieri

2013-06-01

Full Text Available The aptitude of cyclodextrins (CDs to form host-guest complexes has prompted an increase in the development of new drug formulations. In this study, the inclusion complexes of pipemidic acid (HPPA, a therapeutic agent for urinary tract infections, with native β-CD were prepared in solid state by kneading method and confirmed by FT-IR and 1H NMR. The inclusion complex formation was also characterized in aqueous solution at different pH via UV-Vis titration and phase solubility studies obtaining the stability constant. The 1:1 stoichiometry was established by a Job plot and the inclusion mechanism was clarified using docking experiments. Finally, the antibacterial activity of HPPA and its inclusion complex was tested on P. aeruginosa, E. coli and S. aureus to determine the respective EC50s and EC90s. The results showed that the antibacterial activity of HPPA:β-CD against E. coli and S. aureus is higher than that of HPPA. Furthermore, HPPA and HPPA:β-CD, tested on human hepatoblastoma HepG2 and MCF-7 cell lines by MTT assay, exhibited, for the first time, antitumor activities, and the complex revealed a higher activity than that of HPPA. The use of β-CD allows an increase in the aqueous solubility of the drug, its bioavailability and then its bioactivity.

Demands from the school inclusion

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Selma Norberto Matos

2014-04-01

Full Text Available From the implementation of public policies on school inclusion, mainly those directed to the target audience of special education, the number of students with special educational needs in common classes has increased. This fact has helped to compose the picture in schools where the limitations and contradictions of the Brazilian educational system have appeared. Educational actors and authors are challenged to build knowledge able of responding to demands of daily school, concerning living and learning in diversity. Whereas this inclusive process is new in the schools, the study aimed to analyze the demands of teachers from the school inclusion. The research was qualitative and exploratory, and six teachers, their students with special educational needs and three professionals in the Nucleus of Inclusive Education from the Municipal Department of Education took in it. Technique of participant observation, field diary, semi-structured interview and questionnaire were used for data collection, while analysis of content was used for discussion of the data. The results indicate that there are achievements and contradictions in the reality of schools that themselves propose inclusive; advances and limitations resulting from the municipal politics; that the model of performance of the group of special education, in the context analyzed, may be revised or expanded; and that the teachers has demands with regard to public policy, training, and the psychologist.

75 FR 81395 - Minority and Women Inclusion

Science.gov (United States)

2010-12-28

... 2590-AA28 Minority and Women Inclusion AGENCIES: Federal Housing Finance Board; Federal Housing Finance... and the inclusion of women and minorities in all activities. The final rule implements the provisions.... It also requires each regulated entity to establish an Office of Minority and Women Inclusion, or...

75 FR 10446 - Minority and Women Inclusion

Science.gov (United States)

2010-03-08

... 2590-AA28 Minority and Women Inclusion AGENCIES: Federal Housing Finance Board; Federal Housing Finance... minority and women inclusion. Section 1116 of the Housing and Economic Recovery Act of 2008 amended section... Loan Banks to promote diversity and the inclusion of women and minorities in all activities...

Social Inclusion and Metrolingual Practices

Science.gov (United States)

Otsuji, Emi; Pennycook, Alastair

2011-01-01

In this paper, we explore the implications of metrolingual language practices for how we understand social inclusion. A vision of social inclusion that includes bi- and multilingual capacities may comprise an appreciation of a diversity of languages other than English, and the skills and capabilities of multilingual language users, yet it is all…

Inclusive Fitness Maximization:An Axiomatic Approach

OpenAIRE

Okasha, Samir; Weymark, John; Bossert, Walter

2014-01-01

Kin selection theorists argue that evolution in social contexts will lead organisms to behave as if maximizing their inclusive, as opposed to personal, fitness. The inclusive fitness concept allows biologists to treat organisms as akin to rational agents seeking to maximize a utility function. Here we develop this idea and place it on a firm footing by employing a standard decision-theoretic methodology. We show how the principle of inclusive fitness maximization and a related principle of qu...

A Perspective of Inclusion: Challenges for the Future

Directory of Open Access Journals (Sweden)

Maria-Luise Braunsteiner

2013-10-01

Full Text Available The term, inclusion, particularly in the educational setting, is still based on a deficit view. Perceptions of ‘dis’-ability create barriers to true inclusion and are often reinforced through higher education training programs. To promote inclusive values, acceptance of individual and cultural differences must be included in all curricula, not solely within special education. The future of a truly inclusive education relies on a cultural shift that supports and nurtures differences, and views success through a lens not focused on standardization but on diversity. The Index for Inclusion (The Index has been utilized worldwide to support schools, to remove perceived barriers and to establish increasingly inclusive school cultures and practices. The Index aids in the creation of a culture that is dedicated to identifying and reducing barriers to inclusion and increases the learning and participation for all students.

An Inclusive Secondary School in Bratislava

Directory of Open Access Journals (Sweden)

Gajdošová Eva

2016-12-01

Full Text Available The study presents a characterization of an inclusive secondary school in Bratislava and provides information about the forms and methods used in the work of the teachers, school psychologists, special teachers with regard to students with special needs (students with Attention and Hyperactivity Disorder, i.e. ADHD, with learning difficulties, with emotional and behaviour difficulties, etc., who are educated together with mainstream students. It also provides information on the first results of the measurements of the socio-emotional health of the students in the inclusive school, both as to its overall level (covitality index and as to the level of the four psychological dimensions of mental health. The pilot project of the inclusive school confirms that inclusive secondary schools and inclusive education operating within the intentions of positive psychology help the students to develop their cognitive and socio-emotional competences, to create favourable attitudes to diversity, to form the students’ scale of positive values and to encourage positive interpersonal relationships, social cohesion and social classroom climate.

RISKS OF INCLUSIVE EDUCATION

OpenAIRE

M. R. Husnutdinova

2017-01-01

Introduction. Inclusion is a new and unfamiliar phenomenon for most of the Russians which is treated as ensuring equal access to education for all students taking into account a variety of their special educational needs and individual capabilities. Inclusive educational model began to take root in Russia without a broad public debate and today’s parents and teachers were not ready to the cardinal changes caused by transition to the new model of education. In this regard, the studying of dire...

Inclusive Education in Israel

OpenAIRE

O. V. Mayzel

2013-01-01

To get acquainted with the practice of inclusive education in mainstream schools, with professionals who work with special children, to visit the specialist centers to share experiences - all of this was part of an internship program «Early Childhood Education for Children with Special Needs», held in Israel (April 8 -02 May 2013) this year. The country has been selected for an internship, because the practice of inclusive education has been used for over 20 years in Israel. Moreover, a lot ...

Inclusive production at LHC energies

International Nuclear Information System (INIS)

Merino, C.; Pajares, C.; Shabelski, Yu.M.

2011-01-01

We consider the first LHC data for pp collisions in the framework of Regge theory. The integral cross sections and inclusive densities of secondaries are determined by the Pomeron exchange, and we present the corresponding predictions for them. The first measurements of inclusive densities in the midrapidity region are in agreement with these predictions. The contribution of the baryon-number transfer due to String Junction diffusion in the rapidity space is at the origin of the differences in the inclusive spectra of particle and antiparticle in the central region, and this effect could be significant at LHC energies. We discuss the first data of ALICE and LHCb collaborations on the baryon/antibaryon asymmetry at LHC. (orig.)

Diversity at work the practice of inclusion

CERN Document Server

Deane, Barbara R

2014-01-01

This book outlines the key issues involved in framing, designing, and implementing inclusion initiatives for organizations and groups. It offers ideas for helping individuals develop competencies for inclusion. It shows how to apply the practices of inclusion and provides a unified model by employing diverse voices to address a range of related topics in multiple contexts. It also contains examples of how diversity and inclusion has worked in a variety of settings. The book is includes information from topic experts, including internal and external change agents and academics.

Endomorphisms on half-sided modular inclusions

International Nuclear Information System (INIS)

Svegstrup, Rolf Dyre

2006-01-01

In algebraic quantum field theory we consider nets of von Neumann algebras indexed over regions of the space time. Wiesbrock [''Conformal quantum field theory and half-sided modular inclusions of von Neumann algebras,'' Commun. Math. Phys. 158, 537-543 (1993)] has shown that strongly additive nets of von Neumann algebras on the circle are in correspondence with standard half-sided modular inclusions. We show that a finite index endomorphism on a half-sided modular inclusion extends to a finite index endomorphism on the corresponding net of von Neumann algebras on the circle. Moreover, we present another approach to encoding endomorphisms on nets of von Neumann algebras on the circle into half-sided modular inclusions. There is a natural way to associate a weight to a Moebius covariant endomorphism. The properties of this weight have been studied by Bertozzini et al. [''Covariant sectors with infinite dimension and positivity of the energy,'' Commun. Math. Phys. 193, 471-492 (1998)]. In this paper we show the converse, namely, how to associate a Moebius covariant endomorphism to a given weight under certain assumptions, thus obtaining a correspondence between a class of weights on a half-sided modular inclusion and a subclass of the Moebius covariant endomorphisms on the associated net of von Neumann algebras. This allows us to treat Moebius covariant endomorphisms in terms of weights on half-sided modular inclusions. As our aim is to provide a framework for treating endomorphisms on nets of von Neumann algebras in terms of the apparently simpler objects of weights on half-sided modular inclusions, we lastly give some basic results for manipulations with such weights

The P2 of Wheat yellow mosaic virus rearranges the endoplasmic reticulum and recruits other viral proteins into replication-associated inclusion bodies.

Science.gov (United States)

Sun, Liying; Andika, Ida Bagus; Shen, Jiangfeng; Yang, Di; Chen, Jianping

2014-06-01

Viruses commonly modify host endomembranes to facilitate biological processes in the viral life cycle. Infection by viruses belonging to the genus Bymovirus (family Potyviridae) has long been known to induce the formation of large membranous inclusion bodies in host cells, but their assembly and biological roles are still unclear. Immunoelectron microscopy of cells infected with the bymovirus Wheat yellow mosaic virus (WYMV) showed that P1, P2 and P3 are the major viral protein constituents of the membranous inclusions, whereas NIa-Pro (nuclear inclusion-a protease) and VPg (viral protein genome-linked) are probable minor components. P1, P2 and P3 associated with the endoplasmic reticulum (ER), but only P2 was able to rearrange ER and form large aggregate structures. Bioinformatic analyses and chemical experiments showed that P2 is an integral membrane protein and depends on the active secretory pathway to form aggregates of ER membranes. In planta and in vitro assays demonstrated that P2 interacts with P1, P3, NIa-Pro or VPg and recruits these proteins into the aggregates. In vivo RNA labelling using WYMV-infected wheat protoplasts showed that the synthesis of viral RNAs occurs in the P2-associated inclusions. Our results suggest that P2 plays a major role in the formation of membranous compartments that house the genomic replication of WYMV. © 2013 BSPP AND JOHN WILEY & SONS LTD.

Renal pathophysiologic role of cortical tubular inclusion bodies.

Science.gov (United States)

Radi, Zaher A; Stewart, Zachary S; Grzemski, Felicity A; Bobrowski, Walter F

2013-01-01

Renal tubular inclusion bodies are rarely associated with drug administration. The authors describe the finding of renal cortical tubular intranuclear and intracytoplasmic inclusion bodies associated with the oral administration of a norepinephrine/serotonin reuptake inhibitor (NSRI) test article in Sprague-Dawley (SD) rats. Rats were given an NSRI daily for 4 weeks, and kidney histopathologic, ultrastructural pathology, and immunohistochemical examinations were performed. Round eosinophilic intranuclear inclusion bodies were observed histologically in the tubular epithelial cells of the renal cortex in male and female SD rats given the NSRI compound. No evidence of degeneration or necrosis was noted in the inclusion-containing renal cells. By ultrastructural pathology, inclusion bodies consisted of finely granular, amorphous, and uniformly stained nonmembrane-bound material. By immunohistochemistry, inclusion bodies stained positive for d-amino acid oxidase (DAO) protein. In addition, similar inclusion bodies were noted in the cytoplasmic tubular epithelial compartment by ultrastructural and immunohistochemical examination.  This is the first description of these renal inclusion bodies after an NSRI test article administration in SD rats. Such drug-induced renal inclusion bodies are rat-specific, do not represent an expression of nephrotoxicity, represent altered metabolism of d-amino acids, and are not relevant to human safety risk assessment.

Social inclusion policy: Producing justice or retribution?

Directory of Open Access Journals (Sweden)

Kym Macfarlane

2010-10-01

Full Text Available The notion of social inclusion has currently gained extraordinary credence in Australia. Policy incorporating social inclusion abounds across all discipline areas with the federal government for the first time instituting a government portfolio for this area, headed by the Deputy Prime Minister. Such a move indicates the importance of managing aspects of inclusion across all sectors, in a country where diversity abounds. However, this focus on inclusion can prove highly problematic, when it becomes such an integral part of policy formulation and of the assumptions, omissions and contradictions that policy produces. This paper examines how policy discourse produces ways of thinking about inclusion/exclusion. Using three vignettes, the author applies the theories of Michel Foucault to argue that the discursive production of such inclusive policy works to simultaneously exclude by categorising particular types of individuals and families as “proper” participants in society. The author contends that understandings of propriety relating to the inclusion/exclusion binary reinscribe each other, in ways that situate particular citizens outside of possibilities for “success” in social and systemic participation. Such understanding is highlighted by a conceptual examination of the ways in which discursively produced notions of propriety become normalised. Keywords: bricolage, discourse, authorised knowledge, imperative discourse, regimes of truth

Pre-Service Educators' Attitudes towards Inclusive Education

Science.gov (United States)

Mdikana, Andile; Ntshangase, Sibusiso; Mayekiso, Tokozile

2007-01-01

The inclusion of learners with special educational needs in general education is becoming more prevalent. As a result various special education researchers have begun to examine the success of inclusion, as well as the attitudes and beliefs of general educators towards the inclusion of learners with disabilities in the general education classroom.…

Advanced functional evolution equations and inclusions

CERN Document Server

Benchohra, Mouffak

2015-01-01

This book presents up-to-date results on abstract evolution equations and differential inclusions in infinite dimensional spaces. It covers equations with time delay and with impulses, and complements the existing literature in functional differential equations and inclusions. The exposition is devoted to both local and global mild solutions for some classes of functional differential evolution equations and inclusions, and other densely and non-densely defined functional differential equations and inclusions in separable Banach spaces or in Fréchet spaces. The tools used include classical fixed points theorems and the measure-of non-compactness, and each chapter concludes with a section devoted to notes and bibliographical remarks. This monograph is particularly useful for researchers and graduate students studying pure and applied mathematics, engineering, biology and all other applied sciences.

Is inclusive education a human right?

Science.gov (United States)

Gordon, John-Stewart

2013-01-01

In this article, I question the general idea that inclusive education--i.e., to teach all students in one class--is a moral human right. The following discussion shows that the widespread view in disability studies that there is a moral human right to inclusive education can be reasonably called into question by virtue of the proposed counter arguments, but without denying that inclusive education is of utmost importance. Practically speaking, the legal human right to inclusive education is of great practical value for impaired students, and for their basic right to be free from discrimination in education, since their concern thereby gains great legal and moral force. But, theoretically speaking, this particular human right lacks an attainable consensus concerning proper moral justification. © 2013 American Society of Law, Medicine & Ethics, Inc.

Measuring Inclusive Education Outcomes in Alberta, Canada

Science.gov (United States)

Loreman, Tim

2014-01-01

This study details the results of a review of the academic and public sector literature on measuring inclusive education in large systems. It highlights some outcomes drawn from the international literature on inclusion that might be indicative of the presence and quality of inclusive education in an effort to develop a set of outcomes for…

Nonlinear elastic inclusions in isotropic solids

KAUST Repository

Yavari, A.; Goriely, A.

2013-01-01

We introduce a geometric framework to calculate the residual stress fields and deformations of nonlinear solids with inclusions and eigenstrains. Inclusions are regions in a body with different reference configurations from the body itself and can

An Adaptable Seismic Data Format

Science.gov (United States)

Krischer, Lion; Smith, James; Lei, Wenjie; Lefebvre, Matthieu; Ruan, Youyi; de Andrade, Elliott Sales; Podhorszki, Norbert; Bozdağ, Ebru; Tromp, Jeroen

2016-11-01

We present ASDF, the Adaptable Seismic Data Format, a modern and practical data format for all branches of seismology and beyond. The growing volume of freely available data coupled with ever expanding computational power opens avenues to tackle larger and more complex problems. Current bottlenecks include inefficient resource usage and insufficient data organization. Properly scaling a problem requires the resolution of both these challenges, and existing data formats are no longer up to the task. ASDF stores any number of synthetic, processed or unaltered waveforms in a single file. A key improvement compared to existing formats is the inclusion of comprehensive meta information, such as event or station information, in the same file. Additionally, it is also usable for any non-waveform data, for example, cross-correlations, adjoint sources or receiver functions. Last but not least, full provenance information can be stored alongside each item of data, thereby enhancing reproducibility and accountability. Any data set in our proposed format is self-describing and can be readily exchanged with others, facilitating collaboration. The utilization of the HDF5 container format grants efficient and parallel I/O operations, integrated compression algorithms and check sums to guard against data corruption. To not reinvent the wheel and to build upon past developments, we use existing standards like QuakeML, StationXML, W3C PROV and HDF5 wherever feasible. Usability and tool support are crucial for any new format to gain acceptance. We developed mature C/Fortran and Python based APIs coupling ASDF to the widely used SPECFEM3D_GLOBE and ObsPy toolkits.

Migration of brine inclusions in salt

International Nuclear Information System (INIS)

Pigford, T.H.

1982-01-01

Theories of the migration of brine inclusions in salt are interpreted as simple physical processes, and theories by Russian and U.S. workers are shown to yield the same results. The migration theory is used to predict threshold temperature gradients below which migration of brine inclusions should not occur. The predicted threshold gradients are compared with the temperature gradients expected at the Waste Isolation Pilot Plant in New Mexico. The theory of a threshold gradient helps explain the existence of brine inclusions in natural salt deposits

NMR spectroscopic characterization of {beta}-cyclodextrin inclusion complex with vanillin

Energy Technology Data Exchange (ETDEWEB)

Pirnau, Adrian; Bogdan, Mircea; Floare, Calin G, E-mail: adrian.pirnau@itim-cj.r [National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath, 400293 Cluj-Napoca (Romania)

2009-08-01

The inclusion of vanillin by {beta}-cyclodextrin was investigated by {sup 1}H NMR. The continuous variation technique was used to evidence the formation of soluble 1:1 complex in aqueous solution. The association constant of vanillin with {beta}-cyclodextrin has been obtained at 298 K by fitting the experimental chemical shifts differences, {Delta}{delta}{sub obs} {delta}{sub free} - {delta}{sub obs} of the observed guest and host protons, with a non-linear regression method. Besides the effective association constant, the fitting procedure allows a precise determination of all chemical shift parameters characterizing the pure complex. They can by used for an analysis of the geometry of the molecular complex in solution.

Co-producing social inclusion: the structure/agency conundrum.

Science.gov (United States)

Clifton, A; Repper, J; Banks, D; Remnant, J

2013-08-01

There is a raft of policy guidelines indicating that mental health nurses should be increasing the social inclusion of mental health service users. Despite this there is no universally accepted definition of social inclusion and there is a dearth of empirical evidence on the successful outcome of increasing inclusion for mental health service users. Recognizing the lack of clarity surrounding the concept we have a produced a social inclusion framework to assist mental health professionals and service users to co-produce social inclusive outcomes. Although we agree that social inclusion can be a positive aspect of recovery, we question the extent to which mental health nurses and service users in co-production can overcome the social, economic and political structures that have created the social exclusion in the first place. An understanding and appreciation of the structure/agency conundrum is required if mental health nurses are to engage with service users in an attempt to co-produce socially inclusive outcomes. © 2012 John Wiley & Sons Ltd.

Collosion and Absorption Behaviors of Inclusions on Refractory

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Ding-Guo Z.

2017-06-01

Full Text Available The paper is dedicated to analysis the inclusion behavior in steel using theoretical calculation and simulation of water. The aim is to establish collision and absorption model of inclusions on refractory. The article discusses the variation of critical stay speed and critical shear with the radius of inclusions in the process of colliding, rebounding and absorbing. The results show the critical stay speed and critical shear of alumina respectively surpasses 1 cm·s−1 and 1 N·m−2, while titanium dioxide separately exceeds 4 cm·s−1 and 10 N·m−2 for the inclusions that radius is less than 2.5 μm. If the inclusions occur rebound after colliding, the inclusions that radius is less than 7 μm will still be absorbed by the surface, while the inclusions that radius is more than 10 μm can easily reenter the steel. The model coincides with the water simulation results and it is of good adaptability.

FACILITATION AS A TOOL FOR INCLUSIVE PROCESSES IN CLASSROOMS

DEFF Research Database (Denmark)

Riis Jensen, Charlotte

2014-01-01

A Danish survey shows that teachers find 25 % of the students challenging and having behavior problems in a way that undermine the idea of inclusive education (Nordahl, 2011). Allan (2008) emphasizes furthermore that there seems to be some insecurity about how to develop inclusive environment...... within schools and how to arrange inclusive teaching. As a consequence several municipalities in Denmark have employed inclusive supervisors to assist teachers through in developing inclusive education. My study concerns how dialectic processes between supervisors within the field of inclusive education...... and teachers influence on inclusive processes in the classrooms. Furthermore, my study focuses on strategies, methods and approaches that are used by the supervisors to support teachers in order to develop inclusive education. I have studied four different facilitation settings with teachers and supervisors...

Deformability of Oxide Inclusions in Tire Cord Steels

Science.gov (United States)

Zhang, Lifeng; Guo, Changbo; Yang, Wen; Ren, Ying; Ling, Haitao

2018-04-01

The deformation of oxide inclusions in tire cord steels during hot rolling was analyzed, and the factors influencing their deformability at high and low temperatures were evaluated and discussed. The aspect ratio of oxide inclusions decreased with the increasing reduction ratio of the steel during hot rolling owing to the fracture of the inclusions. The aspect ratio obtained after the first hot-rolling process was used to characterize the high-temperature deformability of the inclusions. The deformation first increased and then decreased with the increasing (MgO + Al2O3)/(SiO2 + MnO) ratio of the inclusions. It also increased with the decreasing melting temperatures of the inclusions. Young's modulus was used to evaluate the low-temperature deformability of the inclusions. An empirical formula was fitted to calculate the Young's moduli of the oxides using the mean atomic volume. The moduli values of the inclusions causing wire fracture were significantly greater than the average. To reduce fracture in tire cord steel wires during cold drawing, it is proposed that inclusions be controlled to those with high SiO2 content and extremely low Al2O3 content. This proposal is based on the hypothesis that the deformabilities of oxides during cold drawing are inversely proportional to their Young's moduli. The future study thus proposed includes an experimental confirmation for the abovementioned predictions.

Forum, Dedicated to Inclusive Education

Directory of Open Access Journals (Sweden)

Vachkov I.V.

2015-06-01

Full Text Available 26 – 27 of February 2015 in Kazan, in the University of Management “TISBI” been held National (All-Russian forum of promotion of ideas and principles of inclusive education (with international participants “Study and live together: open space of inclusion”. During the work of Forum the most topical questions of inclusive education implement in Russian Federation been discussed.

Enacting understanding of inclusion in complex contexts: classroom ...

African Journals Online (AJOL)

Hennie

2015-08-14

Aug 14, 2015 ... Dan Tlale. Department of Inclusive Education, College of Education, University of South Africa, Pretoria, South Africa ..... challenges and teachers' understanding of inclusive ..... agency.org/sites/default/files/Profile-of-Inclusive-.

What semi-inclusive data say about clusters

International Nuclear Information System (INIS)

Arneodo, A.; Plaut, G.

1976-01-01

A global analysis of inclusive high-energy multi-particle production data in the cluster model framework is extended to semi-inclusive data. The cluster model embodies leading particle effects and kinematical constraints, which are shown to be of great importance. It appears that models with light clusters decaying on average into approximately equal to 2 charged particles, with a rapidity width delta approximately equal to 0.6 - 0.7 and a distribution much narrower than a Poisson-type, allow one to fit in a nice way both inclusive and semi-inclusive data. It is pointed out that the most constraining semi-inclusive data are those regarding longitudinal correlations, which definitely exclude heavy cluster models, whereas the data on zone characteristics only bear out that a non-negligible percentage of clusters have to carry an electric charge. (Auth.)

The Acceptance of Students with Physical Disabilities by Their Peers in Inclusive and Non-Inclusive Schools in Tehran

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Narges Adib-Sereshki

2005-07-01

Full Text Available Objective: The present research determines the level of peer acceptance of students with physical disabilities in inclusive and non-inclusive schools. A number of studies which have sought to identify the influential factors in the success of inclusive education, have pointed out the acceptance of special need student by his/her regular peers to be a significant variable. Materials & Methods: This is a descriptive investigation. The instrument utilized was the Acceptance Scale (Voelts, 1980. The upper elementary level version that we were used consists of 34 items, two are general friendship items, two are veridicalite items, and the remaining items are acceptance items.Three response options are provided for each item,I agree, I disagree, and maybe. For such reliability, a Spearman-Brown corrected split-half reliability index of +.82 was reported, as well as an alpha coefficient of +.77. A test –retest stability coefficient of .68 was obtained by retesting a sample of 101 children on two occasions separated by three weeks. In Iran, with test retest on 72 students we got Reliability coefficient of .83. The sample includes 179 student boys and girls in grades three to five who had classmates with physical disability in their elementary schools in Tehran. This sample was randomly selected from each of the five different regions in the city of Tehran. In addition, for the purpose of comparison, a sample of fifty-five students in similar grades was studied in regular schools. The effect of gender and type of school (inclusive vs. non-inclusive on students’ acceptance of a peer with physical disability all were assessed. Results: Results indicated that acceptance level is similar in boys and in girls in inclusive schools. The girl and boy students in inclusive schools demonstrated a significantly higher level of peer acceptance than their pupils in non-inclusive schools. This difference was much more noticeable in boy students. The lowest level

inclusions revisited

Directory of Open Access Journals (Sweden)

S. Migórski

1995-01-01

Full Text Available In this paper we confirm the validity of some recent results of Hu, Lakshmikantham, Papageorgiou [4] and Papageorgiou [13] concerning the existence and relaxation for nonlinear evolution inclusions. We fill a gap in the proofs of these results due to the use of incorrect Nagy's compactness embedding theorem.

In situ mobility of uranium in the presence of nitrate following sulfate-reducing conditions.

Science.gov (United States)

Paradis, Charles J; Jagadamma, Sindhu; Watson, David B; McKay, Larry D; Hazen, Terry C; Park, Melora; Istok, Jonathan D

2016-04-01

Reoxidation and mobilization of previously reduced and immobilized uranium by dissolved-phase oxidants poses a significant challenge for remediating uranium-contaminated groundwater. Preferential oxidation of reduced sulfur-bearing species, as opposed to reduced uranium-bearing species, has been demonstrated to limit the mobility of uranium at the laboratory scale yet field-scale investigations are lacking. In this study, the mobility of uranium in the presence of nitrate oxidant was investigated in a shallow groundwater system after establishing conditions conducive to uranium reduction and the formation of reduced sulfur-bearing species. A series of three injections of groundwater (200 L) containing U(VI) (5 μM) and amended with ethanol (40 mM) and sulfate (20 mM) were conducted in ten test wells in order to stimulate microbial-mediated reduction of uranium and the formation of reduced sulfur-bearing species. Simultaneous push-pull tests were then conducted in triplicate well clusters to investigate the mobility of U(VI) under three conditions: 1) high nitrate (120 mM), 2) high nitrate (120 mM) with ethanol (30 mM), and 3) low nitrate (2 mM) with ethanol (30 mM). Dilution-adjusted breakthrough curves of ethanol, nitrate, nitrite, sulfate, and U(VI) suggested that nitrate reduction was predominantly coupled to the oxidation of reduced-sulfur bearing species, as opposed to the reoxidation of U(IV), under all three conditions for the duration of the 36-day tests. The amount of sulfate, but not U(VI), recovered during the push-pull tests was substantially more than injected, relative to bromide tracer, under all three conditions and further suggested that reduced sulfur-bearing species were preferentially oxidized under nitrate-reducing conditions. However, some reoxidation of U(IV) was observed under nitrate-reducing conditions and in the absence of detectable nitrate and/or nitrite. This suggested that reduced sulfur-bearing species may not be fully effective at

Data science implications in diamond formation and craton evolution

Science.gov (United States)

Pan, F.; Huang, F.; Fox, P. A.

2017-12-01

Diamonds are so-called "messengers" from the deep Earth. Fluid and mineral inclusions in diamonds could reflect the compositions of fluids/melts and wall-rocks in which diamond formed. Recently many diamond samples are examined to study the water content in the mantle transition zone1, the mechanism of diamond formation2 and the mantle evolution history3. However, most of the studies can only explain local activities. Therefore, an overall project of data grouping, comparison and correlation is needed, but limited progress has been made due to a lack of benchmark datasets on diamond formation and effective computing algorithms. In this study, we start by proposing the very first complete and easily-accessible dataset on mineral and fluid inclusions in diamonds. We rescue, collect and organize the data available from papers, journals and other publications resources ([2-4] and more), and then apply several state-of-the-art machine learning methods to tackle this earth science problem by clustering diamond formation process into distinct groups primarily based on the compositions, the formation temperature and pressure, the age and so on. Our ongoing work includes further data exploration and training existing models. Our preliminary results show that diamonds formed from older cratons usually have higher formation temperature. Also peridotitic diamonds take a much larger population than the ecologitic ones. More details are being discovered when we finish constructing the database and training our model. We expect the result to demonstrate the advantages of using machine learning and data science in earth science research problems. Our methodology for knowledge discovery are very general and can be broadly applied to other earth science research problems under the same framework.[1] Pearson et al, Nature (2014); [2] Tomlinson et al, EPSL (2006); [3] Weiss et al, Nature (2016); [4] Stachel and Harris, Ore Geology Reviews (2008); Weiss et al, EPSL (2013)

AN ANALYSIS OF SOCIAL INCLUSION IN EU

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HARALAMBIE GEORGE ALIN

2017-08-01

Full Text Available Social inclusion, a dynamic process of stringent topicality, manifested in the community space, is constituted in a subject with multiple reverberations on contemporary society. From this perspective, the growing interest of the Member States in social inclusion is due to the widening of existing inequalities in terms of people's living standards due to the deterioration of economic well-being. A growing number of studies on social cohesion at the level of the countries of the European Union tried to identify the similarities and disparities between Member States in the process of social inclusion. The paper evaluated and compared the existing disparities between the 28 EU countries, based on a set of social indicators that provide an insight into social inclusion. The methodology used implied a cluster analysis based on the method of k-means, which allowed me to form a grouping of Member States based on indicators of social inclusion. The results of the analysis reveal significant differences between the countries of the European Union regarding social inclusion due to factors of a political, economic and social nature. Understanding the mechanism of manifestation and correction of the level of social inclusion can provide, in this sense, explanations and solutions in capitalizing the economic potential by developing specific policies to the existing social imbalances.

Advancing diversity through inclusive excellence in nursing education.

Science.gov (United States)

Bleich, Michael R; MacWilliams, Brent R; Schmidt, Bonnie J

2015-01-01

Nurse leaders call for a more diverse nursing workforce, but too few address the concept of inclusion as a recruitment and retention strategy or as part of improving the academic learning milieu. This article addresses organizational considerations of diversity and inclusion as part of the agenda established by the Association of American Colleges and Universities for inclusive excellence, building on the idea that academic environments only become excellent when an inclusive climate is reached. Six organizational strategies to inclusion are presented from the authors' experiences, some structural and others behavioral: admissions processes, invisibility, absence of community, promotion and tenure, exclusion, and tokenism. A call for structural and behavioral adaptions within nursing education to advance an inclusive excellence agenda is presented. Copyright © 2015 Elsevier Inc. All rights reserved.

Diversifying Geoscience by Preparing Faculty as Workshop Leaders to Promote Inclusive Teaching and Inclusive Geoscience Departments

Science.gov (United States)

Macdonald, H.; Manduca, C. A.; Beane, R. J.; Doser, D. I.; Ebanks, S. C.; Hodder, J.; McDaris, J. R.; Ormand, C. J.

2017-12-01

Efforts to broaden participation in the geosciences require that faculty implement inclusive practices in their teaching and their departments. Two national projects are building the capacity for faculty and departments to implement inclusive practices. The NAGT/InTeGrate Traveling Workshops Program (TWP) and the Supporting and Advancing Geoscience Education in Two-Year Colleges (SAGE 2YC) project each prepares a cadre of geoscience educators to lead workshops that provide opportunities for faculty and departments across the country to enhance their abilities to implement inclusive teaching practices and develop inclusive environments with the goal of increasing diversity in the geosciences. Both projects prepare faculty to design and lead interactive workshops that build on the research base, emphasize practical applications and strategies, enable participants to share their knowledge and experience, and include time for reflection and action planning. The curriculum common to both projects includes a framework of support for the whole student, supporting all students, data on diversity in the geosciences, and evidence-based strategies for inclusive teaching and developing inclusive environments that faculty and departments can implement. Other workshop topics include classroom strategies for engaging all students, addressing implicit bias and stereotype threat, and attracting diverse students to departments or programs and helping them thrive. Online resources for each project provide support beyond the workshops. The TWP brings together educators from different institutional types and experiences to develop materials and design a workshop offered to departments and organizations nationwide that request the workshop; the workshop leaders then customize the workshop for that audience. In SAGE 2YC, a team of leaders used relevant literature to develop workshop materials intended for re-use, and designed a workshop session for SAGE 2YC Faculty Change Agents, who

Topological structure of the solution set for evolution inclusions

CERN Document Server

Zhou, Yong; Peng, Li

2017-01-01

This book systematically presents the topological structure of solution sets and attractability for nonlinear evolution inclusions, together with its relevant applications in control problems and partial differential equations. It provides readers the background material needed to delve deeper into the subject and explore the rich research literature.  In addition, the book addresses many of the basic techniques and results recently developed in connection with this theory, including the structure of solution sets for evolution inclusions with m-dissipative operators; quasi-autonomous and non-autonomous evolution inclusions and control systems;evolution inclusions with the Hille-Yosida operator; functional evolution inclusions; impulsive evolution inclusions; and stochastic evolution inclusions. Several applications of evolution inclusions and control systems are also discussed in detail.  Based on extensive research work conducted by the authors and other experts over the past four years, the information p...

Inclusive Education in Government Primary Schools: Teacher Perceptions

OpenAIRE

Itfaq Khaliq Khan; Shujahat Haider Hashmi; Nabeela Khanum

2017-01-01

The perceptions of primary school teachers towards inclusive education was investigated in mainstream government schools of Islamabad capital territory where inclusive education was being supported by Sight savers and other international organizations. The study was carried out involving 54 teachers in six randomly selected primary schools. The sampled group comprised both, teachers trained in inclusive education and teachers working in same schools, but not trained in inclusive education. Pu...

The Effect of Cooling Conditions on the Evolution of Non-metallic Inclusions in High Manganese TWIP Steels

Science.gov (United States)

Wang, Yu-Nan; Yang, Jian; Xin, Xiu-Ling; Wang, Rui-Zhi; Xu, Long-Yun

2016-04-01

In the present study, the effect of cooling conditions on the evolution of non-metallic inclusions in high manganese TWIP steels was investigated based on experiments and thermodynamic calculations. In addition, the formation and growth behavior of AlN inclusions during solidification under different cooling conditions were analyzed with the help of thermodynamics and dynamics. The inclusions formed in the high manganese TWIP steels are classified into nine types: (1) AlN; (2) MgO; (3) CaS; (4) MgAl2O4; (5) AlN + MgO; (6) MgO + MgS; (7) MgO + MgS + CaS; (8) MgO + CaS; (9) MgAl2O4 + MgS. With the increase in the cooling rate, the volume fraction and area ratio of inclusions are almost constant; the size of inclusions decreases and the number density of inclusions increases in the steels. The thermodynamic results of inclusion types calculated with FactSage are consistent with the observed results. With increasing cooling rate, the diameter of AlN decreases. When the cooling rate increases from 0.75 to 4.83 K s-1, the measured average diameter of AlN decreases from 4.49 to 2.42 μm. Under the high cooling rate of 4.83 K s-1, the calculated diameter of AlN reaches 3.59 μm at the end of solidification. However, the calculated diameter of AlN increases to approximately 5.93 μm at the end of solidification under the low cooling rate of 0.75 K s-1. The calculated diameter of AlN decreases with increasing cooling rate. The theoretical calculation results of the change in diameter of AlN under the different cooling rates have the same trend with the observed results. The existences of inclusions in the steels, especially AlN which average sizes are 2.42 and 4.49 μm, respectively, are not considered to have obvious influences on the hot ductility.

Hamiltonian inclusive fitness: a fitter fitness concept.

Science.gov (United States)

Costa, James T

2013-01-01

In 1963-1964 W. D. Hamilton introduced the concept of inclusive fitness, the only significant elaboration of Darwinian fitness since the nineteenth century. I discuss the origin of the modern fitness concept, providing context for Hamilton's discovery of inclusive fitness in relation to the puzzle of altruism. While fitness conceptually originates with Darwin, the term itself stems from Spencer and crystallized quantitatively in the early twentieth century. Hamiltonian inclusive fitness, with Price's reformulation, provided the solution to Darwin's 'special difficulty'-the evolution of caste polymorphism and sterility in social insects. Hamilton further explored the roles of inclusive fitness and reciprocation to tackle Darwin's other difficulty, the evolution of human altruism. The heuristically powerful inclusive fitness concept ramified over the past 50 years: the number and diversity of 'offspring ideas' that it has engendered render it a fitter fitness concept, one that Darwin would have appreciated.

Arc generation from sputtering plasma-dielectric inclusion interactions

International Nuclear Information System (INIS)

Wickersham, C.E. Jr.; Poole, J.E.; Fan, J.S.

2002-01-01

Arcing during sputter deposition and etching is a significant cause of particle defect generation during device fabrication. In this article we report on the effect of aluminum oxide inclusion size, shape, and orientation on the propensity for arcing during sputtering of aluminum targets. The size, shape, and orientation of a dielectric inclusion plays a major role in determining the propensity for arcing and macroparticle emission. In previous studies we found that there is a critical inclusion size required for arcing to occur. In this article we used high-speed videos, electric arc detection, and measurements of particle defect density on wafers to study the effect of Al 2 O 3 inclusion size, shape, and orientation on arc rate, intensity, and silicon wafer particle defect density. We found that the cross-sectional area of the inclusion exposed to the sputtering plasma is the critical parameter that determines the arc rate and rate of macroparticle emission. Analysis of the arc rate, particle defect density, and the intensity of the optical emission from the arcing plasma indicates that the critical aluminum oxide inclusion area for arcing is 0.22±0.1 mm2 when the sputtering plasma sheath dark-space λ d , is 0.51 mm. Inclusions with areas greater than this critical value readily induce arcing and macroparticle ejection during sputtering. Inclusions below this critical size do not cause arcing or macroparticle ejection. When the inclusion major axis is longer than 2λ d and lies perpendicular to the sputter erosion track tangent, the arcing activity increases significantly over the case where the inclusion major axis lies parallel to the erosion track tangent

Inclusive Education in Government Primary Schools: Teacher Perceptions

Directory of Open Access Journals (Sweden)

Itfaq Khaliq Khan

2017-06-01

Full Text Available The perceptions of primary school teachers towards inclusive education was investigated in mainstream government schools of Islamabad capital territory where inclusive education was being supported by Sight savers and other international organizations. The study was carried out involving 54 teachers in six randomly selected primary schools. The sampled group comprised both, teachers trained in inclusive education and teachers working in same schools, but not trained in inclusive education. Purposive sampling method was used to select the teachers. Structured questionnaire (Likert Scale and structured interview method was used for data collection. The results of the study revealed that inclusive education is considered to be a desirable practice. The teachers believed that all learners regardless of their disabilities should be in regular classrooms and they showed more favorable attitude towards children with mild disabilities, but were not very optimistic about children with severe disabilities. The study also recognized teachers’ capacity as an essential component of inclusive education and recommends that inclusive education should be a part of pre and in-service teacher education.

Inclusion "All Present and Correct?" A Critical Analysis of New Labour's Inclusive Education Policy in England

Science.gov (United States)

Hodkinson, Alan

2013-01-01

Drawing on Derrida this paper considers how inclusive education in England was defined and operationalised within New Labour's educational policy and by those teachers who reconstructed this policy within the confines of schools and individual classrooms. The paper has two critical ambitions. First it argues that the epistemology of inclusion was…

Financial inclusion at scale: An IDRC-Alliance for Financial Inclusion ...

International Development Research Centre (IDRC) Digital Library (Canada)

... to save money for emergencies, to invest in education, or to realize small business ... Alliance for Financial Inclusion. Pays d' institution. Malaysia. Site internet ... Les conclusions d'un programme financé par le CRDI au premier plan de la ...

Exploring the Landscape of Inclusion: Profiles of Inclusive versus Segregated School Districts in the United States

Science.gov (United States)

Marks, Susan Unok; Kurth, Jennifer A.; Bartz, Jody Marie

2014-01-01

Although inclusive education has been increasing in frequency for students with disabilities in the United States, for many students, the opportunity to be educated with their peers without disabilities continues to be out of reach despite decades of efforts by those promoting the vision of inclusion. This exploratory case study used interviews…

On Graph Refutation for Relational Inclusions

Directory of Open Access Journals (Sweden)

Paulo A. S. Veloso

2012-03-01

Full Text Available We introduce a graphical refutation calculus for relational inclusions: it reduces establishing a relational inclusion to establishing that a graph constructed from it has empty extension. This sound and complete calculus is conceptually simpler and easier to use than the usual ones.

Pointlike Inclusion Interactions in Tubular Membranes

NARCIS (Netherlands)

Vahid Belarghou, A.; Idema, T.

2016-01-01

Membrane tubes and tubular networks are ubiquitous in living cells. Inclusions like proteins are vital for both the stability and the dynamics of such networks. These inclusions interact via the curvature deformations they impose on the membrane. We analytically study the resulting membrane

[Separation of gamma linolenic acid from evening primrose oil with urea inclusion--orthogonal experiment of optimizing technological parameters and observation of urea inclusion compound I].

Science.gov (United States)

Wang, Hua; Ling, Man; Xue, Gang; Liu, Fengxia; Guo, Shuxian

2010-05-01

The influence on the urea inclusion compound under different conditions (allocated proportion, time of inclusion, temperature of inclusion) were studied through the orthogonal test, and theoretical reference of urea inclusion process for further optimization wound be offered. The orthogonal experiment was adopted, and microscope was used to observe the shape, aperture size of the urea inclusion compound under different technological parameters, the GC was employed to inspect the purity of GLA. The results indicated that the ratio of fatty acids and urea, inclusion of temperature, time of inclusion had great effect on urea inclusion compound. The three factors and its interactions significantly affected the purity of GLA. The results also showed that the best process was that the ratio of fatty acids and urea was 1 : 3, temperature of inclusion was--15 degrees C, time of inclusion was 24 h. Under the best condition, the purity of GLA reach up to 95.575 9%; and it is feasible to observe the shape and the amount of the urea inclusion compound to reflect and guide the urea inclusion technology.

Football for Inclusion: Examining the Pedagogic Rationalities and the Technologies of Solidarity of a Sports-Based Intervention in Sweden

Directory of Open Access Journals (Sweden)

David Ekholm

2017-06-01

Full Text Available Sports practices have been emphasised in social policy as a means of responding to social problems. In this article we analyse a sports-based social intervention performed in a “socially vulnerable” area in Sweden. We examine the formation of includable citizens in this project, based on interviews with representatives involved in the project. The material is analysed from a governmentality perspective, focusing on how problems and solutions are constructed as being constitutive of each other. The focus of the analysis is on social solidarity and inclusion as contemporary challenges, and how sport, specifically football, is highlighted as a way of creating social solidarity through a pedagogic rationality—football as a means of fostering citizens according to specific ideals of solidarity and inclusion. The formation of solidarity appears not as a mutual process whereby an integrated social collective is created, but rather as a process whereby those affected by exclusion are given the opportunity to individually adapt to a set of Swedish norms, and to linguistic and cultural skills, as a means of reaching the “inside”. Inclusion seems to be possible as long as the “excluded” adapt to the “inside”, which is made possible by the sports-based pedagogy. In conclusion, social problems and social tensions are spatially located in “the Area” of “the City”, whose social policy, of which this sports-based intervention is a part, maintains rather than reforms the social order that creates these very tensions.

Isolation of cell-free bacterial inclusion bodies.

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Rodríguez-Carmona, Escarlata; Cano-Garrido, Olivia; Seras-Franzoso, Joaquin; Villaverde, Antonio; García-Fruitós, Elena

2010-09-17

Bacterial inclusion bodies are submicron protein clusters usually found in recombinant bacteria that have been traditionally considered as undesirable products from protein production processes. However, being fully biocompatible, they have been recently characterized as nanoparticulate inert materials useful as scaffolds for tissue engineering, with potentially wider applicability in biomedicine and material sciences. Current protocols for inclusion body isolation from Escherichia coli usually offer between 95 to 99% of protein recovery, what in practical terms, might imply extensive bacterial cell contamination, not compatible with the use of inclusion bodies in biological interfaces. Using an appropriate combination of chemical and mechanical cell disruption methods we have established a convenient procedure for the recovery of bacterial inclusion bodies with undetectable levels of viable cell contamination, below 10⁻¹ cfu/ml, keeping the particulate organization of these aggregates regarding size and protein folding features. The application of the developed protocol allows obtaining bacterial free inclusion bodies suitable for use in mammalian cell cultures and other biological interfaces.

Políticas para a inclusão: estudo realizado em uma Escola Estadual de Belo Horizonte Policies for inclusion: study in a State School in Belo Horizonte

Directory of Open Access Journals (Sweden)

Maria Auxiliadora Monteiro Oliveira

2011-12-01

Full Text Available Este trabalho, centrado nas Políticas Públicas para a Educação Inclusiva, enfatiza a formação de professores para trabalharem com alunos que apresentam necessidades educacionais especiais. A pesquisa, realizada em 2007/2008, em uma Escola Estadual de Belo Horizonte, objetivou investigar a capacitação de docentes para essa modalidade de educação e avaliar o processo de inclusão dos mencionados alunos, em uma escola estadual de BH. Metodologicamente, optou-se pela denominada pesquisa "Quali-Quanti", na qual se aplicou um questionário que desenhou o perfil de 25 professoras da escola. Em termos qualitativos, foram entrevistadas 10 docentes, a diretora da escola e a gerente da Diretoria de Educação Especial (DEEP. Em síntese, foram estes os dados coletados: todas as professoras eram favoráveis à Educação Inclusiva; nenhuma delas tinha capacitação para trabalhar com essa educação e, apenas duas conheciam um pouco da legislação sobre a Educação Inclusiva; todas afirmaram tanto ter dificuldade de lidar com os referidos alunos quanto ser significativa a evasão escolar dos mesmos.This article, focusing on Public Policies for Inclusive Education, emphasizes the formation of teachers to work with students who have special educational needs. The survey, conducted in 2007/2008 in a State School in Belo Horizonte aimed to investigate the training of teachers for the education, evaluate the process of inclusion of students mentioned in a government school in BH. Methodologically, we focused on the questionnaire that drew the outline of 25 teachers from the school. Ten teachers were interviewed, the school director and the manager of the Directorate of Special Education (DEEP. In synthesis, these data were collected: all teachers were in favor of Inclusive Education, none of which had capacity to work with this education, only two knew a bit of legislation on inclusive education, all said both have difficulty dealing with those

Inclusion: Something More Than Sitting Together

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Bulbul, Mustafa Sahin

2011-01-01

Awareness about students with learning difficulty brought us to inclusive learning environments. The acceptance was to build collaborative atmospheres in the class. Unfortunately, when teachers are not enthusiastic and adequate to develop the interaction, the inclusive learning environment never occurs. This conclusion bases on this studies…

Irish Mathematics Teachers' Attitudes towards Inclusion

Science.gov (United States)

Whitty, Elaine; Clarke, Marie

2012-01-01

This paper through the theoretical framework of constructive attitude theory explores mathematics teachers' attitudes and pedagogical strategies with reference to inclusive practice. The authors argue that though teachers may have formed positive inclusive attitudes, the translation of these into practice does not always occur and poses…

Implementing inclusive educational practices through partnerships ...

African Journals Online (AJOL)

This study reports on work in progress of a partnership between the University of Stellenbosch and three rural schools in a disadvantaged community, focused on the development of inclusive educational practices such as teaching, assessment and support in inclusive education. Recognizing the changing needs of the ...

Scattering of elastic waves by thin inclusions

International Nuclear Information System (INIS)

Simons, D.A.

1980-01-01

A solution is derived for the elastic waves scattered by a thin inclusion. The solution is asymptotically valid as inclusion thickness tends to zero with the other dimensions and the frequency fixed. The method entails first approximating the total field in the inclusion in terms of the incident wave by enforcing the appropriate continuity conditions on traction and displacement across the interface, then using these displacements and strains in the volume integral that gives the scattered field. Expressions are derived for the far-field angular distributions of P and S waves due to an incident plane P wave, and plots are given for normalized differential cross sections of an oblate spheroidal tungsten carbide inclusion in a titanium matrix

Complexes of technetium with pyrophosphate, etidronate, and medronate

International Nuclear Information System (INIS)

Russell, C.D.; Cash, A.G.

1979-01-01

The reduction of [ 99 Tc]pertechnetate was studied as a function of pH in complexing media of pyrophosphate, methylene diphosphonate (MDP), and ethane-1, hydroxy-1, and 1-diphosphonate (HEDP). Test (sampled d-c) and normal-pulse polarography were used to study the reduction of pertechnetate, and normal-pulse polarography (sweeping in the anodic direction) to study the reoxidation of the products. Below pH 6 TcO 4 - was reduced to Tc(III), which could be reoxidized to Tc(IV). Above pH 10, TcO 4 - was reduced in two steps to Tc(V) and Tc(IV), each of which could be reoxidized to TcO 4 - . Between pH 6 and 10 the results differed according to the ligand present. In pyrophosphate and MDP, TcO 4 - was reduced in two steps to Tc(IV) and Tc(III); Tc(III) could be reoxidized in two steps to Tc(IV) and TcO 4 - . In HEDP, on the other hand, TcO 4 - was reduced in two steps to Tc(V) and Tc(III), and could be reoxidized to Tc(IV) and TcO 4 - . Additional waves were observed; they apparently led to unstable products

Inclusive education and students without special educational needs

NARCIS (Netherlands)

Ruijs, N.M.; van der Veen, I.; Peetsma, T.T.D.

2010-01-01

Background: In the debate on inclusive education, students without special educational needs (SEN) are an important topic. However, there is a lot unknown about differences between these typical students in inclusive and non-inclusive classes. For example, the neutral results that are often found in

Inclusive Education in Higher Education: Challenges and Opportunities

Science.gov (United States)

Moriña, Anabel

2017-01-01

Implementing the principles of inclusive education within higher education can be challenging. Inclusive education was originally developed for younger students, prior to its application within higher education. However, as more students with disabilities successfully complete their early schooling, the need to move towards inclusive practices…

26 CFR 26.2642-5 - Finality of inclusion ratio.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Finality of inclusion ratio. 26.2642-5 Section...-5 Finality of inclusion ratio. (a) Direct skips. The inclusion ratio applicable to a direct skip...) Other GSTs. With respect to taxable distributions and taxable terminations, the inclusion ratio for a...

Language and Social Inclusion: Unexplored Aspects of Intercultural Communication

Science.gov (United States)

Musgrave, Simon; Bradshaw, Julie

2014-01-01

Social inclusion policy in Australia has largely ignored key issues of communication for linguistic minorities, across communities and with the mainstream community. In the (now disbanded) Social Inclusion Board's reports (e.g., Social Inclusion Unit, 2009), the emphasis is on the economic aspects of inclusion, while little attention has been paid…

Formation of light particles in nucleus-nucleus collisions

International Nuclear Information System (INIS)

Zagrebaev, V.; Penionzhkevich, Yu.

1993-01-01

The principal experimental results on the yield of the light charged particles in nucleus-nucleus collisions at the low and intermediate energies are reviewed. Inclusive spectra of light particles and their coincidences with the characteristic KX-rays, γ-rays, neutrons, projectile-like fragments, other light particles, fission fragments, and evaporation residues are analyzed. The main theoretical models used for the description of the light particle formation are briefly outlined together with their merits and shortcomings. The unsolved problems of fast light particle formation, in particular, and of nucleus-nucleus interaction dynamics, on the whole, are discussed with the outlooks of new experiments able to clear up some of these problems. (author) 144 refs., 40 figs., 2 tabs

Radial scaling in inclusive jet production at hadron colliders

Science.gov (United States)

Taylor, Frank E.

2018-03-01

Inclusive jet production in p-p and p ¯ -p collisions shows many of the same kinematic systematics as observed in single-particle inclusive production at much lower energies. In an earlier study (1974) a phenomenology, called radial scaling, was developed for the single-particle inclusive cross sections that attempted to capture the essential underlying physics of pointlike parton scattering and the fragmentation of partons into hadrons suppressed by the kinematic boundary. The phenomenology was successful in emphasizing the underlying systematics of the inclusive particle productions. Here we demonstrate that inclusive jet production at the Large Hadron Collider (LHC) in high-energy p-p collisions and at the Tevatron in p ¯ -p inelastic scattering shows similar behavior. The ATLAS inclusive jet production plotted as a function of this scaling variable is studied for √s of 2.76, 7 and 13 TeV and is compared to p ¯ -p inclusive jet production at 1.96 TeV measured at the CDF and D0 at the Tevatron and p-Pb inclusive jet production at the LHC ATLAS at √sNN=5.02 TeV . Inclusive single-particle production at Fermi National Accelerator Laboratory fixed target and Intersecting Storage Rings energies are compared to inclusive J /ψ production at the LHC measured in ATLAS, CMS and LHCb. Striking common features of the data are discussed.

Teachers' knowledge, attitude and practices of inclusive education ...

African Journals Online (AJOL)

This study was conducted to investigate teachers' knowledge, attitude, and practices of inclusive education in Nekemte town and its surrounding government primary schools; and how their knowledge and attitude towards inclusion affect the practice of inclusive education. The participants of the study were primary school ...

40 CFR 35.133 - Programs eligible for inclusion.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Programs eligible for inclusion. 35.133... Programs eligible for inclusion. (a) Eligible programs. Except as provided in paragraph (b) of this section, the environmental programs eligible, in accordance with appropriation acts, for inclusion in a...

Fluid inclusion brine compositions from Palo Duro Basin salt sites

International Nuclear Information System (INIS)

Moody, J.B.

1987-01-01

The fluid inclusion analyses were done on salt samples from Lower San Andres Cycle 4 and 5. The stable isotope composition of the fluid inclusion brines was measured on duplicate samples taken from the same fluid inclusion brine for correlation of geochemical content with the stable isotopic content. The analyzed Palo Duro Basin salt fluid inclusions are predominantly one phase, i.e., the presence of a fluid only. However, many of the larger fluid inclusions do have a small vapor bubble. This liquid/vapor ratio is so high in these vapor-containing fluid inclusions that their behavior in a thermal gradient would be almost identical to that of all liquid inclusions. Closely associated with the fluid inclusions are cryptomelane where some fibers penetrate into halite host crystal. The fluid inclusions have a wide variability in content for those components that were analyzed, even within the same salt type. The fluid inclusion brines are also acidic, ranging from 3 to 6 as measured with pH test papers

Students' Perspectives on LGBTQ-Inclusive Curriculum

Science.gov (United States)

Snapp, Shannon D.; Burdge, Hilary; Licona, Adela C.; Moody, Raymond L.; Russell, Stephen T.

2015-01-01

Implementing curriculum that is inclusive of lesbian, gay, bisexual, transgender, queer, and questioning (LGBTQ) people has the potential to create an equitable learning environment. In order to learn more about students' experiences of LGBTQ-inclusive curriculum, 26 high school students with diverse racial/ethnic, sexual, and gender identities…

Moving Forward in Inclusive Education Research

Science.gov (United States)

Erten, Ozlem; Savage, Robert Samuel

2012-01-01

This paper aims to address conceptual and methodological challenges of doing research in the field of inclusive education and revisit school effectiveness research literature to inform future research. First, we present the rationale for inclusive education and briefly review the evolution of special needs education. Then, we discuss limitations…