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Sample records for renal por radiofrecuencia

  1. Termoablación con radiofrecuencia de tumores del parenquima renal

    OpenAIRE

    Calvo González, Raúl

    2015-01-01

    Evaluar la técnica de Termoablación mediante Radiofrecuencia (RFA) como opción terapéutica para el tratamiento de masas renales de pequeño tamaño. Evaluar la técnica Termoablación mediante Radiofrecuencia en términos de eficacia oncológica. Evaluación del protocolo de seguimiento posterior a la aplicación de técnicas ablativas para el tratamiento de tumores del parénquima renal. Evaluar el perfil de seguridad de la técnica de Termoablación mediante Radiofrecuencia determinando las c...

  2. Sistema de identificación y posicionamiento local por radiofrecuencia (RFID)

    OpenAIRE

    Acosta Henríquez, Giovanni Francisco; Cáceres Chiquillo, Juan José; Morales Hernández, Rigoberto Alfonso; Quintanilla Padilla, Ricardo Edgardo

    2010-01-01

    Se presenta en este documento el informe final de ejecución técnica del proyecto de investigación aplicada “Sistema de identificación y posicionamiento local por radiofrecuencia (RFID)”, efectuado por la Escuela Especializada en Ingeniería ITCA-FEPADE, el cual forma parte de los primeros proyectos del programa FIES (Fondo de Investigación de Educación Superior). Dicho proyecto se enmarca dentro de las áreas de la Tecnología de la información y comunicaciones (TICs) y Automatización, por tal r...

  3. Estenosis de venas pulmonares post ablación por radiofrecuencia

    Directory of Open Access Journals (Sweden)

    Marcelo Guzzi

    2011-06-01

    Full Text Available Es importante estar atento ante la aparición de síntomas respiratorios luego de la realización de un procedimiento de ablación por radiofrecuencia en el tratamiento de la fibrilación auricular, pues la estenosis de venas pulmonares (EVP tiene una incidencia de entre 1 y 3% y puede aparecer hasta en los dos años posteriores al procedimiento1. Presentamos el caso de un paciente de 41 años de sexo masculino, que ingresó por un cuadro de hemoptisis y toracodinia de tres semanas de evolución, con antecedente de ablación por radiofrecuencia 6 meses antes de la admisión. La angiotomografía no evidenció tromboembolismo pulmonar (TEP y la angiorresonancia detectó hipoperfusión deI lóbulo superior del pulmón izquierdo (LSI. Debido a los antecedentes de ablación se solicitó angiotomografía de venas pulmonares, que evidenció estenosis de la vena del LSI. Se realizó estudio hemodinámico con dilatación y colocación de stent.

  4. Sistemas de telecomunicaciones basados en identificación por radiofrecuencia para aplicaciones académicas, de logística y transporte de pasajeros

    OpenAIRE

    Ramírez Echeverry, John Jairo

    2012-01-01

    Este artículo presenta resultados de tres proyectos desarrollados por el Grupo de Investigación en Electrónica de Altas Frecuencias y Telecomunicaciones, de la Universidad Nacional de Colombia (CMUN), en los cuales se han implementado sistemas de telecomunicaciones inalámbricos, basados en tecnologías de identificación por radiofrecuencia (RFID), para el entrenamiento médico de estudiantes de neonatología, manejo de logística de eventos y monitoreo de rutas y arribo de vehículos de transporte...

  5. Arquitectura de software de una aplicación móvil para desarrollar un sistema de identificación por radiofrecuencia

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    Gerardo Lagunes García

    2015-02-01

    Full Text Available Un sistema RFID (Radio Frequency Identification, Identificación por Radiofrecuencia ayuda a identificar toda clase de objetos por medio de etiquetas o tags RFID, un sistema de este tipo tiene como funciones principales saber cuántos bienes se tienen y donde se encuentran ubicados, controlando estos elementos, el apoyo al inventario aumenta porque lo mantiene actualizado con información real. El presente trabajo propone una arquitectura de software para desarrollar una aplicación móvil que es parte de un sistema RFID, que sirve de apoyo al inventario del Instituto Tecnológico de Orizaba y así también se presentan los resultados (aplicaciones que se generaron a partir de las arquitecturas propuestas.

  6. Accidente cerebrovascular isquémico asociado con ablación por radiofrecuencia de reentrada nodal Ischemic stroke associated with radio frequency ablation for nodal reentry

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    Juan C Díaz Martínez

    2010-04-01

    Full Text Available La taquicardia por reentrada nodal es la causa más común de taquicardia supraventricular paroxística; en aquellos pacientes en quienes el manejo farmacológico no es efectivo o deseado la ablación por radiofrecuencia es un excelente método terapéutico dada su alta tasa de curación. Aunque en términos generales dichos procedimientos son rápidos y seguros, se han descrito varias complicaciones entre las que sobresale el accidente cerebrovascular isquémico. Se presenta el caso de una paciente de 41 años con episodios de taquicardia por reentrada nodal a repetición, que fue llevada a ablación por radiofrecuencia. En el post-operatorio inmediato se evidenció déficit neurológico focal con isquemia en el territorio de la arteria cerebral media derecha, tras lo cual se realizó angiografía con intento de angioplastia y abxicimab y posteriormente infusión local de activador de plasminógeno tisular (rtPA con adecuado resultado clínico y angiográfico.Atrioventricular nodal reentry tachycardia is the most common type of paroxismal supraventricular tachycardia. In those patients in whom drug therapy is not effective or not desired, radio frequency ablation is an excellent therapeutic method. Although overall these procedures are fast and safe, several complications among which ischemic stroke stands out, have been reported. We present the case of a 41 year old female patient with repetitive episodes of tachycardia due to nodal reentry who was treated with radiofrequency ablation. Immediately after the procedure she presented focal neurologic deficit consistent with ischemic stroke in the right medial cerebral artery territory. Angiography with angioplastia and abxicimab was performed and then tissue plasminogen activator (rtPA was locally infused, with appropriate clinical and angiographic outcome.

  7. Mapeo y ablación por radiofrecuencia a cielo abierto: un caso de taquicardia ventricular refractaria en anomalía de Ebstein

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    Alejandro Olaya

    2017-07-01

    Full Text Available La anomalía de Ebstein es una enfermedad congénita, caracterizada por el desplazamiento y la adherencia de la válvula tricúspide. Las valvas septal y posterior se implantan en posiciones más inferiores, causando insuficiencia tricuspídea, esta condición de forma progresiva genera dilatación y deterioro de la función sistólica ventricular derecha. Comúnmente se asocia a otras entidades, principalmente, a la comunicación interauricular y las arritmias mediadas por vías accesorias. La muerte súbita ocurre en estadios avanzados, usualmente relacionados con episodios de taquicardia ventricular. Este reporte describe un caso de anomalía de Ebstein y tormenta arrítmica, que se sometió a ablación del sustrato arrítmico endo y epicárdico en la porción atrializada del ventrículo derecho, que presentó como complicación intraprocedimiento la perforación del ventrículo, el taponamiento cardiaco y la necesidad urgente de la reparación quirúrgica, realizándose en el intraoperatorio una segunda ablación por radiofrecuencia a cielo abierto con el objetivo de eliminar los potenciales tardíos y los fragmentados remanentes en el área de bajo voltaje de la escara. Veintidós semanas después de la ablación se implantó un cardiodesfibrilador subcutáneo para prevención secundaria de la muerte súbita; en el seguimiento a 14 meses no hubo terapias apropiadas del dispositivo.

  8. SISTEMAS DE IDENTIFICACIÓN POR RADIOFRECUENCIA, CÓDIGO DE BARRAS Y SU RELACIÓN CON LA GESTIÓN DE LA CADENA DE SUMINISTRO

    OpenAIRE

    ALEXANDER CORREA ESPINAL; CARLOS ESTEBAN ÁLVAREZ LÓPEZ; RODRIGO ANDRÉS GÓMEZ MONTOYA

    2010-01-01

    El articulo muestra, a través del análisis de libros, artículos científicos y algunos estudios existentes, el estado del arte y la relación entre los sistemas de identificación (código de barras y radiofrecuencia) y la gestión de la cadena de suministro, en aplicaciones significativas a nivel mundial y de Colombia. Para ello, se compilan conceptos generales de los sistemas de identificación presentando sus definiciones, componentes de hardware/software, aplicaciones en la cadena de suministro...

  9. SISTEMAS DE IDENTIFICACIÓN POR RADIOFRECUENCIA, CÓDIGO DE BARRAS Y SU RELACIÓN CON LA GESTIÓN DE LA CADENA DE SUMINISTRO

    Directory of Open Access Journals (Sweden)

    ALEXANDER CORREA ESPINAL

    2010-01-01

    Full Text Available El articulo muestra, a través del análisis de libros, artículos científicos y algunos estudios existentes, el estado del arte y la relación entre los sistemas e identificación (código de barras y radiofrecuencia y la gestión de la cadena de suministro, en aplicaciones significativas a nivel mundial y de Colombia. Para ello, se compilan conceptos generales de los sistemas de identificación presentando sus definiciones, componentes de hardware/software, aplicaciones en la cadena de suministro y el uso que grandes, medianas y pequeñas empresas le otorgan. El estudio pone en evidencia la importancia que estas tecnologías tienen para mejorar el desempeño y la trazabilidad, simplificar operaciones, reducir costos y agilizar los flujos de información en la cadena de suministro.

  10. Dos décadas de seguimiento exitoso de la primera ablación de arritmias por catéter de radiofrecuencia realizado en la historia de la medicina del Paraguay

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    Osmar Antonio Centurión

    2015-08-01

    Full Text Available La técnica de mapeo endocárdico durante el estudio electrofisiológico ha sido extensamente empleada en el análisis de las taquicardias paroxísticas supraventriculares (TPS. Mediante este mapeo endocárdico y el análisis meticuloso de los electrogramas endocárdicos y los respectivos intervalos de conducción, es posible localizar el sitio de origen de las arritmias y así facilitar su tratamiento ablativo por medio de catéteres de radiofrecuencia. Se describe el caso de un hombre de 29 años con síndrome de Wolff-Parkinson-White (WPW que manifiestó que presentaba varios episodios documentados de TPS con serio compromiso hemodinámico que motivaba su frecuente internación en terapia intensiva. El mapeo electrofisiológico endocárdico meticuloso demostró la presencia de un haz anómalo de Kent auriculoventricular izquierdo en posición posteroseptal. El período refractario absoluto del haz anómalo de Kent fue de 240 ms. La primera emisión de radiofrecuencia a través de un catéter adecuadamente posicionado previo terminó la taquicardia. La taquicardia permaneció no inducible a partir de entonces. En estas dos décadas de seguimiento clínico, el paciente no ha presentado ni un solo episodio de taquicardia. La curación definitiva generada por la ablación del haz anómalo de Kent ha proporcionado un cambio drástico, total y beneficioso en la calidad de vida al paciente. Los beneficios clínicos y socioeconómicos son mayores cuanto más temprano en la evolución se realice el procedimiento de ablación de arritmias.

  11. Sistemas de identificación por radiofrecuencia, código de barras y su relación con la gestión de la cadena de suministro

    National Research Council Canada - National Science Library

    Alexander Correa Espinal

    2010-01-01

    ... y la relación entre los sistemas de identificación (código de barras y radiofrecuencia) y la gestión de la cadena de suministro, en aplicaciones significativas a nivel mundial y de Colombia...

  12. Experiencia preliminar del tratamiento quirúrgico de la fibrilación auricular con ablación por radiofrecuencia Preliminary experience of the surgical treatment of auricular fibrillation with radiofrequency ablation

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    Alejandro Villar Inclán

    2008-03-01

    Full Text Available INTRODUCCIÓN. La fibrilación auricular es la arritmia cardíaca preoperatoria más frecuente entre los pacientes de cirugía cardiovascular. Entre las modalidades de tratamiento se hallan el tratamiento médico, la cardioversión transtorácica o intracardíaca con choque de corriente continua sincronizada, la estimulación (marcapasos, la ablación con catéter y la cirugía, en la cual se incluyen los métodos quirúrgicos propiamente dichos, las técnicas de catéteres para ablación y las técnicas mixtas. MÉTODOS. Se realizó un estudio prospectivo descriptivo de 25 pacientes operados de patología mitral con fibrilación auricular crónica, a los cuales se realizó ablación con radiofrecuencia durante 60 s, con 150 W de energía y control de temperatura de 60 ºC. Se comenzó el procedimiento solamente alrededor de las venas pulmonares y luego se incluyeron estas. A todos los pacientes se les realizó seguimiento posoperatorio por espacio de un año y la eficacia del procedimiento se evaluó en éxito y fracaso. RESULTADOS. La mejor eficacia del tratamiento estuvo relacionada con la menor edad de los pacientes. A medida que el tiempo de evolución de la fibrilación auricular fue mayor, aumentó el ritmo de fracaso del procedimiento y de igual manera ocurrió con el tamaño de la aurícula izquierda. Se observó que, al año, el 76 % de los pacientes se encontraban en ritmo sinusal y ninguna de las complicaciones que se presentaron tuvieron relación con el método en sí. CONCLUSIONES. Consideramos que la ablación con radiofrecuencia intraoperatoria durante el tratamiento quirúrgico de la válvula mitral constituyó un proceder efectivo y seguro en el tratamiento de pacientes con fibrilación auricular crónica asociadaINTRODUCTION. Auricular fibrillation is the most frequent preoperative cardiac arrhytmia among the patients undergoing cardiovascular surgery. The medical treatment, the transthoracic or intracardiac cardioversion

  13. Ablación por radiofrecuencia de vía anómala en paciente con agenesia de la vena cava inferior

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    Carlos A. Gómez

    2015-05-01

    Full Text Available Describimos un caso de una paciente de sexo femenino de 55 años de edad a quien se le diagnosticó síndrome de Wolff-Parkinson-White, y al ser llevada al procedimiento de ablación se le encuentra agenesia de la vena cava inferior, con continuidad hacia las cavidades cardiacas derechas a través de la vena ácigos. La realización posterior del procedimiento a través de dicha vena se consideró exitosa, pero ante la recurrencia de las alteraciones electrocardiográficas y nuevos episodios de taquicardia se le realizó nuevo estudio electrofisiológico y ablación por vía yugular interna derecha con éxito. Presentamos además una revisión de la literatura sobre este tópico.

  14. Degradación de las propiedades ópticas de películas semiconductoras amorfas de nitruro de silicio a-SiN producidas por pulverización catódica de radiofrecuencia

    OpenAIRE

    Zegarra Sierra, Katia

    2015-01-01

    En el presente trabajo se encuentran compilados el estudio de propiedades ópticas y vibracionales de películas delgadas amorfas de nitruro de silicio depositadas bajo diferentes presiones de trabajo. Las películas han sido preparadas mediante la técnica de pulverización catódica de radiofrecuencia en los laboratorios de la Sección de la PUCP usando un objetivo de silicio cristalino en una atmosfera de nitrógeno y argón. Se ha investigado el efecto de oxidación bajo dos puntos de vista: primer...

  15. Sistemas de identificación por radiofrecuencia, código de barras y su relación con la gestión de la cadena de suministro

    Directory of Open Access Journals (Sweden)

    Alexander Correa Espinal

    2010-07-01

    Full Text Available El articulo muestra, a través del análisis de libros, artículos científicos y algunos estudios existentes, el estado del arte y la relación entre los sistemas de identificación (código de barras y radiofrecuencia y la gestión de la cadena de suministro, en aplicaciones significativas a nivel mundial y de Colombia. Para ello, se compilan conceptos generales de los sistemas de identificación presentando sus definiciones, componentes de hardware/software, aplicaciones en la cadena de suministro y el uso que grandes, medianas y pequeñas empresas le otorgan. El estudio pone en evidencia la importancia que estas tecnologías tienen para mejorar el desempeño y la trazabilidad, simplificar operaciones, reducir costos y agilizar los flujos de información en la cadena de suministro.

  16. Satisfacción del alumnado en actividades de grupo reducido en Medicina mediante el uso de mandos de respuesta interactiva basados en radiofrecuencias

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    Miguel Angel Barbancho

    2017-07-01

    El uso de mandos de radiofrecuencia se ha mostrado como una herramienta útil como apoyo a la docencia en grupos reducidos, facilitando una buena adquisición de competencias específicas y un elevado grado de satisfacción por parte del alumnado.

  17. Cirurgia vídeo-assistida para a ablação da fibrilação atrial isolada por radiofrequência bipolar Cirugía videoasistida para ablación de fibrilación atrial aislada por radiofrecuencia bipolar Videothoracoscopy for isolated atrial fibrillation ablation through bipolar radiofrequency

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    Alexandre Siciliano Colafranceschi

    2009-10-01

    Full Text Available FUNDAMENTO: A prevalência da fibrilação atrial, os gastos com o sistema de saúde e a elevada morbidade e mortalidade associadas a ela, têm justificado a procura por novas abordagens terapêuticas. OBJETIVO: Avaliar a reprodutibilidade da técnica cirúrgica, a segurança e os resultados inicias da cirurgia vídeo-assistida para a ablação da fibrilação atrial isolada com radiofrequência bipolar. MÉTODOS: Dez pacientes (90% homens com fibrilação atrial (50% paroxística sintomática e refratária à terapia medicamentosa, sem doença cardíaca que requeresse cirurgia concomitante, foram submetidos à ablação da arritmia guiada por toracoscopia, no período de maio de 2007 a maio de 2008. Variáveis clínicas, laboratoriais e de imagem foram prospectivamente coletadas antes, durante e no seguimento pós-operatório. RESULTADOS: A cirurgia foi realizada conforme o planejado em todos os pacientes. Não houve lesão iatrogênica de estruturas intratorácicas ou óbitos. No seguimento médio de seis meses, 80% dos pacientes estão livres de fibrilação atrial. Houve melhora significativa dos sintomas de insuficiência cardíaca classe funcional New York Heart Association (2,4 ± 0,5 para 1,6 ± 0,7; p = 0,011. Não houve evidência de estenose de veias pulmonares à angiotomografia, nesta série. CONCLUSÃO: A cirurgia vídeo-assistida para o tratamento da fibrilação atrial é reprodutível e segura. Há melhora evolutiva dos sintomas de insuficiência cardíaca após a cirurgia.FUNDAMENTO: La prevalencia de la fibrilación atrial, los gastos con el sistema de salud y la elevada morbilidad y mortalidad asociados a ésta, justifican la búsqueda de nuevos abordajes terapéuticos. OBJETIVO: Evaluar la reproducibilidad de la técnica quirúrgica, la seguridad y los resultados iniciales de la cirugía videoasistida para la ablación de la fibrilación atrial aislada con radiofrecuencia bipolar. MÉTODOS: Diez pacientes (90% hombres con

  18. Automatización de Tarjetas Electrónicas de Radiofrecuencia Empleadas en Autos de Radio Control Nikko

    OpenAIRE

    Héctor Ulises Rodríguez Marmolejo; J. Rafael Molina Contreras

    2007-01-01

    El presente artículo da a conocer la automatización realizada en un lote de tarjetas electrónicas de radiofrecuencia usadas en autos de radio control de la marca nikko. El modelo k7-RC de autos de radio control profesional después de unas cuantas horas de funcionamiento falla la etapa de potencia del sistema de tracción, debido a la alta demanda de corriente eléctrica por parte del motor. Se tienen dos alternativas, la primera de ellas es adquirir la tarjeta electrónica del nuevo modelo desde...

  19. INSUFICIENCIA RENAL AGUDA POR CISPLATINO: REPORTE DE UN CASO

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    Rodriguez Macías EL

    2016-01-01

    Full Text Available Cisplatin nephrotoxicity should always be considered as a potential cause of renal damage in acute renal failure installed in the context of its use. Among its mechanisms of renal functional impairment are: acute tubular necrosis, proximal tubular and loop of Henle dysfunctions, as well as the deterioration of various organelles, especially the mitochondria.

  20. FISIOPATOLOGÍA DE LA INSUFICIENCIA RENAL AGUDA POR CISPLATINO

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    Rodriguez Macías EL

    2013-09-01

    Full Text Available Cisplatin is one of the major antineoplastic used for treatment of tumors such as testicular, ovarian, cervical, lung, bladder and head, among others. It has been described various types of toxicities induced by cisplatin, but the renal is the main one. This toxicity consist sof an acute reduction in renal plasma flow and a decline in glomerular filtration and installation of a tubular necrosis, with predominant involvement of the distal tubules and accumulation of cellular debris (lumen obstruction. Other mechanisms involved in renal injury are microangiopathy and pro-inflammatory mediators. We conclude that the nephrotoxicity caused by cisplatin can induce renal failure in which tubular structural damage predominates.

  1. Tratamiento de dolor lumbar crónico mediante radiofrecuencia pulsada y aplicación de esteroides em forma epidural: estudio comparativo Tratamento da dor lombar crônica por meio da radiofrequência pulsada e a aplicação de esteroides na forma epidural: estudo comparativo Treatment of chronic low back pain by means of pulsed radiofrequency and application of steroids in epidural form: comparative study

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    Matín Tejeda-Barreras

    2010-03-01

    Full Text Available OBJETIVOS: valorar el resultado clínico de mejoría de dolor y de escala funcional lumbar de radiofrecuencia pulsada, en comparación con aplicación de esteroides epidurales, en el tratamiento de pacientes con dolor lumbar crónico. TIPO DE INVESTIGACIÓN: un ensayo clínico ciego y simple. MÉTODOS: el estudio se realizó dese mayo de 2008 a julio de 2009. Fueron 40 pacientes, de los medios institucional y privado, de la ciudad de Hermosillo, Sonora, en el México, con dolor lumbar crónico. Se aplicó el cuestionario de Roland-Morris y la escala visual análoga de dolor, previa a tratamiento, y posterior al mismo. No se registraron pérdidas de pacientes en el seguimiento. Se analizaron los resultados de las diferentes variables (edad, sexo, ocupación, evolución, trabajo de carga, incapacidad, hallazgos de imagenología, estableciendo una comparación con la prueba de χ2. RESULTADOS: fueron muy similares en ambos grupos de tratamiento (χ2=2.8283, p=0.093, con dos casos complicados por punción en el grupo de esteroides epidurales, sin casos complicados por el procedimiento de radiofrecuencia pulsada. Los valores de χ2 no muestran diferencias estadísticamente significativas, con valores de p de 0.09 a 0.9. CONCLUSIÓN: la aplicación de radiofrecuencia pulsada es tan eficaz como la aplicación de esteroides epidurales para el manejo del dolor lumbar crónico.OBJETIVOS: avaliar o resultado clínico de melhoria da dor e da escala funcional lombar de radiofrequência pulsada, comparada com a aplicação de esteroides epidurais, no tratamento de pacientes com dor lombar crônico. TIPO DE INVESTIGAÇÃO: um ensaio clínico cego e simples. MÉTODOS: o estudo foi realizado desde maio de 2008 a julho de 2009. Foram utilizados 40 pacientes, dos meios institucional e privado, da cidade de Hermosillo, Sonora, no México, com dor lombar crônico. Foi aplicado o questionário de Roland-Morris e a escala visual análoga de dor, com tratamento pr

  2. FISIOPATOLOGÍA DE LA INSUFICIENCIA RENAL AGUDA POR CISPLATINO

    OpenAIRE

    Rodriguez Macías EL

    2013-01-01

    Cisplatin is one of the major antineoplastic used for treatment of tumors such as testicular, ovarian, cervical, lung, bladder and head, among others. It has been described various types of toxicities induced by cisplatin, but the renal is the main one. This toxicity consist sof an acute reduction in renal plasma flow and a decline in glomerular filtration and installation of a tubular necrosis, with predominant involvement of the distal tubules and accumulation of cellular debris (lumen...

  3. Insuficiência renal aguda por picada de abelhas: relato de casos Acute renal failure following bee stings: case reports

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    Elizabeth De Francesco Daher

    2009-04-01

    Full Text Available Rabdomiólise é uma síndrome caracterizada por injúria muscular, mais freqüentemente decorrente de esmagamento e traumas musculares. No entanto, a rabdomiólise pode ter também causas não traumáticas, como por exemplo, picadas de abelhas africanizadas. Descrevemos dois casos de rabdomiólise que apresentaram insuficiência renal aguda dialítica após várias picadas de abelhas.Rhabdomyolysis is a syndrome characterized by muscle injury, most frequently due to muscle crushing and trauma. However, it may also be induced by non-traumatic causes, for example by means of stinging by Africanized bees. We describe two cases of rhabdomyolysis that presented dialytic acute renal failure after several bee stings.

  4. UNA PROPUESTA DIDÁCTICA PARA LA CARACTERIZACIÓN DE DISPOSITIVOS Y REDES ELÉCTRICAS DE RADIOFRECUENCIA EN LA BANDA DE 100 KHz A 500 MHz

    OpenAIRE

    Linares y Miranda,R; González-Jaimes,H. E; J López-Bonilla

    2010-01-01

    En este artículo se presenta un esquema didáctico de prueba y medición para la caracterización en el dominio de la frecuencia de componentes y circuitos lineales de radiofrecuencia (RF). El esquema se basa en la observación del comportamiento temporal manifestado por las tensiones incidentes y reflejadas. Éstas se pueden generar cuando se suministran señales sinusoidales de RF en los puertos o terminales de los dispositivos o redes eléctricas bajo estudio. El objetivo principal de este trabaj...

  5. Estudio vascular renal por TC multidetector de 64 canales 64-Multidetector row CT for the Renal Vascular Study

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    Daniela Stoisa

    2009-03-01

    Full Text Available Objetivo: Mostrar las diversas variantes anatómicas vasculares tanto arteriales como venosas en el estudio angiográfico renal por tomografìa computada multidetector (TCMD de 64 canales, dada su implicancia en un eventual planeamiento quirúrgico. Material y métodos: Evaluamos retrospectivamente 26 estudios realizados con tomógrafo Philips Brilliance de 64 canales. Se obtuvieron secuencias sin contraste y postcontraste e.v. en fases arterial y venosa, administrado con bomba inyectora doble cabezal. Para una fase arterial apropiada se utilizó técnica de bolus track. Las imágenes fueron posteriormente procesadas en Workstation Philips Brilliance 190P en un tiempo promedio de 30 minutos y reconstruidas con técnicas MIP y volumétrica. Resultados: Dentro de las variantes anatómicas arteriales, encontramos: bifurcaciones prehiliares (n=3, arterias accesorias (n=4 y arterias polares (n=9. Dentro de las variantes venosas fueron halladas: venas renales múltiples (n=5, venas circumaórticas (n=2, retroaórticas (n=2 y vena tributaria lumbar prominente (n=1. Conclusión: El estudio vascular renal adquiere importancia en el planeamiento quirúrgico en casos de nefrectomías parciales, laparoscópicas y en el transplante renal. Esto otorga suma utilidad al estudio de TCMD de 64 canales por su eficacia diagnóstica, dada la alta calidad de las reconstrucciones obtenidas, llegando a igualar a la angiografía digital, sin ser un método invasivo.Purpose: To show the wide range of anatomical vascular variants, arterial and venous, that can be seen in the angiographic renal study using 64-multidetector-row computed tomography (64-MDCT, due to its importance in an eventual surgical planning. Material and Methods: We have evaluated retrospectively 26 studies that have been done using a 64 channels Philips Brilliance CT scanner. We have obtained non enhanced and both in arterial and venous enhanced sequences. For the injection of the contrast material we

  6. Radiofrequência na dor crônica Radiofrecuencia en el dolor crónico Radiofrequency in chronic pain

    Directory of Open Access Journals (Sweden)

    José Luciano Braun Filho

    2009-06-01

    Full Text Available Radiofrequência (RF é uma técnica minimamente invasiva alvo-seletiva e tem sido usada durante muitos anos para o tratamento de diferentes doenças, como dor lombar crônica, neuralgia trigeminal e outros. Trata-se de uma corrente elétrica alternada com frequência oscilatória de 500.000 hz, que flui através de um eletrodo introduzido percutaneamente. O calor é formado ao redor do eletrodo porque o tecido age como um resistor. Essa técnica pode, portanto, ser usada para causar lesões em tecidos nervosos no tratamento de dor crônica. O objetivo desta revisão é abordar alguns aspectos importantes do mecanismo e evolução da radiofrequência na dor crônica. Serão abordados os aspectos básicos da Física e o mecanismo de ação da radiofrequência, método que tem sido usado para tratar dores crônicas de diferentes etiologias, além da evolução com o advento da radiofrequência pulsátil. O uso da radiofrequência no manejo da dor crônica é uma ferramenta útil em diferentes condições dolorosas e tem sido usada com sucesso por mais de 25 anos. Seu mecanismo de ação ainda não foi totalmente elucidado. A radiofrequência pulsátil é, em particular, uma técnica minimamente destrutiva e poderá ser uma alternativa à forma convencional de tratamento para a dor por radiofrequência.Radiofrecuencia (RF es una técnica mínimamente invasiva con blanco selectivo, y ha sido usada durante muchos años para el tratamiento de diferentes patologías como dolor lumbar crónico, neuralgia trigeminal entre otros. Radiofrecuencia es una corriente eléctrica alternada con frecuencia oscilatoria de 500.000 hz. La corriente fluye por medio de un electrodo introducido percutáneamente y el calor es formado alrededor del electrodo, porque el tejido actúa como una resistencia. Por lo tanto, la radiofrecuencia puede ser usada para causar lesiones en tejidos nerviosos para tratamiento de dolor crónico. El objetivo de esta revisión es abordar

  7. Reporte de insuficiencia renal producida por Leptospira Interrogans Serovar Pomona en Colombia

    OpenAIRE

    Fortunato Ospino; Ligia Sedano de León; Manuel Isaac Gallego

    1988-01-01

    Se describe la presentación de un caso de leptospirosis producida por L. pomona en un paciente de 20 años de edad, trabajadora habitual en un molino de arroz y caracterizado por un síndrome de insuficiencia renal y hepática. El cuadro clínico consistió principalmente en malestar general, anorexia, vómito, fiebre, diarrea, ictericia y hemorragias subconjuntivales. Los exámenes de laboratorio mostraron alteraciones, en los niveles de nitrógeno ureico, creatinina, depuración de creatinina, conce...

  8. Reporte de insuficiencia renal producida por Leptospira Interrogans Serovar Pomona en Colombia

    Directory of Open Access Journals (Sweden)

    Fortunato Ospino

    1988-06-01

    Full Text Available Se describe la presentación de un caso de leptospirosis producida por L. pomona en un paciente de 20 años de edad, trabajadora habitual en un molino de arroz y caracterizado por un síndrome de insuficiencia renal y hepática. El cuadro clínico consistió principalmente en malestar general, anorexia, vómito, fiebre, diarrea, ictericia y hemorragias subconjuntivales. Los exámenes de laboratorio mostraron alteraciones, en los niveles de nitrógeno ureico, creatinina, depuración de creatinina, concentración de cloro, fosfatasa alcalina y bilirrubina directa lo cual podría indicar un daño en el funcionamiento hepático y renal. Las alteraciones en la velocidad de sedimentación, hemoglobina, hematocrito y leucocitos (Tabla 1 explican la anemia e infección ocasionada por la L. pomona en la paciente. El diagnóstico de leptospirosis fue confirmado por el aislamiento del microorganismo de la orina a pesar de no haber detectado anticuerpos en el suero de la paciente. Se pone en evidencia la necesidad de realizar siempre el diagnóstico diferencial con leptospirosis en todo síndrome hepatorrenal, especialmente en los casos con antecedentes epidemiológicos o que por la sintomatología clínica se sospeche la infección.

  9. Amiloidosis renal hereditaria por depósito de apolipoproteína AI: un reto diagnóstico

    Directory of Open Access Journals (Sweden)

    Kelly del Rocío Samillán-Sosa

    2015-05-01

    La amiloidosis por depósito de Apo AI progresa a enfermedad renal crónica terminal en el plazo de de 3 a 15 años. Se diferencia clínicamente de la amiloidosis AL por su menor afectación extrarrenal y su mejor pronóstico. El trasplante renal ofrece una supervivencia del injerto aceptable y el trasplante hepato-renal se podría tener en cuenta en pacientes con disfunción significativa de ambos órganos.

  10. Infección por virus BK en paciente pediátrico trasplantado renal BK virus infection in a pediatric renal transplant recipient

    Directory of Open Access Journals (Sweden)

    R. Bonaventura

    2005-09-01

    Full Text Available El poliomavirus humano BK causa infección primaria asintomática en la niñez, estableciendo latencia principalmente en el tracto urinario. En individuos con alteración en la inmunidad celular se puede producir su reactivación desencadenando patología a nivel renal. Por estas razones es particularmente importante en la población pediátrica trasplantada renal, en la que puede producir la infección primaria cuando el paciente está inmunosuprimido. En nuestro trabajo se realizó el seguimiento de un paciente de 5 años trasplantado renal en octubre de 2003 que 45 días post-trasplante sufrió un deterioro del órgano injertado. Desde la fecha del trasplante hasta junio de 2004 se produjeron 3 episodios de alteración en la función renal, durante los cuales se analizaron muestras de sangre, orina, biopsia renal y líquido de linfocele. Para el diagnóstico difererencial entre rechazo agudo versus causa infecciosa se emplearon técnicas de detección para los virus BK, CMV y ADV, además del estudio citológico del tejido renal. Los resultados obtenidos junto con la clínica del paciente indican un probable caso de infección por BK. La importancia de realizar el diagnóstico diferencial entre rechazo agudo y la infección por BK radica en que la conducta en cuanto a la terapia inmunosupresora es opuesta en cada caso.BK Human Polyomavirus causes an asymptomatic primary infection in children, then establishing latency mainly in the urinary tract. Viral reactivation can lead to renal pathology in individuals with impaired cellular immune response. This is particularly important in pediatric transplant recipients, who can suffer a primary infection when immunosupressed. We followed up the case of a 5 years old patient who received a renal transplant in October 2003, and presented damaged graft 45 days after the intervention. The patient suffered 3 episodes of renal function failure between October 2003 and June 2004. Blood, urine, renal biopsy

  11. Hidrocolpo por ectopia ureteral em hemivagina associado a displasia renal: relato de caso e revisão da literatura

    OpenAIRE

    Barba,Mario Flores; Ogawa,Renata Emy; Tanuri,Uenis; Tanuri,Anna; Koch,Vera H.; Oliveira,Luiz Antônio Nunes de

    2004-01-01

    Os autores apresentam um caso de displasia renal associada a ectopia ureteral vaginal homolateral, com uretero-hidronefrose contralateral devida a compressão por hidrocolpo causado pela ectopia e por um septo vaginal oblíquo. Os exames de imagem utilizados foram urografia excretora, cistografia, ultra-sonografia, tomografia computadorizada e cintilografia renal com Tc-99m-DMSA. Foi realizada revisão da literatura sobre casos de hidrocolpo associado a malformações urinárias.

  12. Intoxicação por veneno de cobra: necrose symetrica da cortex renal: uremia

    Directory of Open Access Journals (Sweden)

    A. Penna de Azevedo

    1938-01-01

    Full Text Available Em um caso fatal de ophidismo, em individuo de 15 annos de edade, picado por uma cobra jararaca (Bothrops jararaca na face externa da perna direita e que veio a fallecer 26 dias apoz o accidente, os A.A, descrevem as lesões anatomo-pathologicas encontradas e as modificações do metabolismo, evidenciadas pelos exames chimicos do sangue. As principaes alterações existentes, acham-se localisadas nos rins os quaes apresentam lesões de glomerulonephrite diffusa e o aspecto typico da necrose cortical symmetrica. Como alterações de maior significação observam-se ainda lesões vasculares de grande intensidade e constituidas essencialmente por processo de endoarterite productiva. A necrose symmetrica da cortex renal, a vista das intensas alterações vasculares (endoarterite productiva que acarretaram a obliteração das arterías, é considerada como a consequencia immediata de taes lesões vasculares. Os vasos renaes, séde do processo inflammatorio, são as arterias interlobar, arciforme e interlobular, mas principalmente as arteriolares da camada cortical. O processo de endoarterite assume sempre o carater progressivo, de modo que a luz vascular vae sendo aos poucos, totalmente obstruida. Ao contrario do que se tem observado nos casos de necrose cortical symmetrica, citados na literatura, em que as alterações parenchymatosas são consequentes a thrombose dos vasos reanes, no caso presente esse aspecto não foi verificado mas tão sómente a existencia da endoarterite productiva obliterante. Consideram os A.A. as lesões renaes no caso que estudaram, como a resultante da actuação lenta e prolongada do veneno de cobra sobre as estructuras renaes, baseados nos seguintes factos já conhecidos e admittidos: eliminação do veneno de cobra pelos rins; capacidade do mesmo veneno, determinar a glomerulo-nephrite diffusa e acção do veneno de cobra sobre o endothelio vascular, facilitada essencialmente pela funcção especifica do orgão. As

  13. Diseño y desarrollo de un sistema de control por radiofrecuencia para la optimización de la gestión del inventario del almacén de envases en una planta industrial de fabricación de pinturas

    OpenAIRE

    RAMÍREZ MARTÍ, DAVID

    2016-01-01

    [ES] El sistema diseñado consiste en reflejar en el registro de existencias las entradas, las salidas y los movimientos internos en el almacén mediante un software desarrollado por el Departamento de Informática. Para ello se marca como objetivo la creación de dos nuevos almacenes en el sistema: uno provisional y otro definitivo con ubicaciones identificadas mediante etiquetas con código de barras para el stock de envases y tapas. Para traspasar las existencias del almacén provisi...

  14. Participação de mastocitos na lesão renal induzida por isquemia/reperfusão

    OpenAIRE

    Felipe Caetano Beraldo

    2007-01-01

    Resumo: A lesão renal causada pela isquemia é a principal causa de insuficiência renal aguda [IRA] em rins nativos e transplantados. A fisiopatologia da IRA induzida por isquemia/reperfusão [I/R] envolve alterações na hemodinâmica renal, lesão de células endoteliais e tubulares e os processos inflamatórios, que resultam na ativação e lesão de células endoteliais, aumento da adesão entre células endoteliais e leucócitos, migração de leucócitos para o tecido afetado e comprometimento microvascu...

  15. Insuficiência renal aguda em pacientes internados por insuficiência cardíaca descompensada - Reincade

    OpenAIRE

    Barros,Larissa Cristina Nascimento de; Silveira,Fábio Serra; Silveira,Marcos Serra; Morais,Thamara Carvalho; Nunes,Marco Antônio Prado; Bastos,Kleyton de Andrade

    2012-01-01

    INTRODUÇÃO: Insuficiência renal aguda (IRA) acontece com frequência em pacientes críticos, porém a significância clínica de sua ocorrência não tem sido determinada na insuficiência cardíaca descompensada (ICD). OBJETIVOS: Estudar a ocorrência e valor prognóstico da IRA em pacientes internados por ICD e avaliar comparativamente com aqueles sem a complicação o perfil clínico-laboratorial e a mortalidade intra-hospitalar. MÉTODOS: Estudo prospectivo em 85 pacientes internados em terapia intensiv...

  16. N-acetilcisteína e deferoxamina protegem contra insuficiência renal aguda induzida por isquemia/reperfusão em ratos

    OpenAIRE

    Bernardi,Roberto Meister; Constantino,Larissa; Machado,Roberta Albino; Vuolo,Francieli; Budni,Patricia; Ritter,Cristiane; Dal-Pizzol,Felipe

    2012-01-01

    OBJETIVO: Os antioxidantes são largamente utilizados em modelos animal para prevenir lesão renal após isquemia/reperfusão. Uma questão importante é se os benefícios dos antioxidantes são aditivos ou não. O objetivo deste estudo foi investigar os efeitos protetores da N-acetilcisteína com deferoxamina, em modelo animal, de isquemia renal/traumatismo por reperfusão. MÉTODOS: A isquemia renal bilateral foi mantida por 45 minutos. N-acetilcisteína, deferoxamina ou ambas foram administradas na aor...

  17. Neuropatía por virus BK post trasplante renal diagnostico y seguimiento por PCR en tiempo real BK virus nephropathy after renal transplantation: Diagnosis and prognosis by real time PCR

    Directory of Open Access Journals (Sweden)

    Marcela Echavarria

    2007-12-01

    Full Text Available La nefropatía producida por el virus BK puede llevar a la pérdida del trasplante renal. El diagnóstico etiológico es importante debido a que la clínica no permite diferenciar entre nefropatía por virus BK y rechazo agudo, en donde los tratamientos de estas dos entidades son diametralmente opuestos. El desarrollo reciente de métodos moleculares muy sensibles y específicos como PCR y PCR en tiempo real para virus BK permiten un diagnóstico de certeza en forma rápida y cuantificar la carga viral presente. El diagnóstico de nefropatía por virus BK se realiza por inmunohistoquímica en una biopsia renal, pero dada la naturaleza multifocal de las lesiones, la sensibilidad no siempre es del 100%. Los nuevos métodos de PCR para detectar virus BK en sangre y orina contribuyen al diagnóstico de nefropatía de una manera más normatizada y menos invasiva. Más aún, la cuantificación del virus BK en sangre por PCR en tiempo real, ha demostrado ser útil en el diagnóstico y monitoreo de esta enfermedad. En este trabajo se presenta el caso de una paciente transplantada renal con nefropatía por virus BK y el desarrollo de un método de PCR en tiempo real para la detección de virus BK en sangre y orina. Esta nueva metodología confirmó el diagnóstico de nefropatía por virus BK lo que permitió un cambio en el esquema de inmunosupresión y la instauración de un tratamiento que pudo ser monitorizado utilizando la carga viral.BK virus nephropathy may lead to kidney transplant failure. BK infection and acute rejection are clinically undistinguishable, therefore diagnosis of these entities is critical to establish the correct treatment. The new molecular methods using PCR and real time PCR have significantly contributed to the rapid and sensitive diagnosis of BK virus. Furthermore, viral load determination in plasma has significantly been associated with BK virus nephropathy. Definite diagnosis of nephropathy requires renal biopsy, although

  18. Effect of sildenafil in renal ischemia/reperfusion injury in rats Efeito do sildenafil na lesão renal por isquemia/reperfusão em ratos

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    Paulo José de Medeiros

    2010-12-01

    Full Text Available PURPOSE: To evaluate the effect of sildenafil, administered prior to renal ischemia/reperfusion (I/R, by scintigraphy and histopathological evaluation in rats. METHODS: Twenty-four rats were divided randomly into two groups. They received 0.1 ml of 99mTechnetium-etilenodicisteine intravenous, and a baseline (initial renal scintigraphy was performed. The rats underwent 60 minutes of ischemia by left renal artery clamping. The right kidney was not manipulated. The sildenafil group (n=12 received orally 1 mg/kg of sildenafil suspension 60 minutes before ischemia. Treatment with saline 0.9% in the control group (n=12. Half of the rats was assessed after 24 hours and half after seven days I/R, with new renal scintigraphy to study differential function. After euthanasia, kidneys were removed and subjected to histopathological examination. For statistical evaluation, Student t and Mann-Whitney tests were used. RESULTS: In the control group rats, the left kidneys had significant functional deficit, seven days after I/R, whose scintigraphic pattern was consistent with acute tubular necrosis, compared with the initial scintigraphy (pOBJETIVO: Estudar o efeito do sildenafil, administrado previamente à isquemia/reperfusão (I/R renal, em avaliações cintilográficas e histopatológicas em ratos. MÉTODOS: Vinte e quatro ratos Wistar foram aleatoriamente distribuídos em dois grupos. Os animais receberam 0,1 ml IV de 99mTecnécio-Etilenodicisteína, foram submetidos à cintilografia renal inicial e em seguida submetidos a isquemia no rim esquerdo, com oclusão da artéria renal, durante 60 minutos, com posterior reperfusão. O grupo sildenafil (n=12 recebeu previamente 1mg/kg de sildenafil em suspensão 60 minutos antes da isquemia. Solução salina 0,9% foi administrada no grupo controle (n=12. Metade dos animais de cada grupo foi avaliada após 24 horas e a outra metade após sete dias de reperfusão, com nova cintilografia renal. Após eutanásia, os

  19. Reanálisis del estudio ESHOL: mortalidad por todas las causas considerando riesgos de competición y tiempo-dependientes para trasplante renal

    Directory of Open Access Journals (Sweden)

    Francisco Maduell

    2016-03-01

    Conclusiones: Los resultados del reanálisis del estudio ESHOL se confirman cuando se aplica el análisis en la población por intención de tratar sin censurar ninguna observación y considerando la mortalidad por todas las causas dependiente del tiempo y del riesgo competitivo del trasplante renal.

  20. ' RENAL

    African Journals Online (AJOL)

    METASTASE OSSEUSE: SOLITAIRE D'UN ADENOCARCINOME RENAL. Fig. 2: TDM ... du gène de résistance aux médicaments. NIDR1. ... vie. La néphrectomie trouve sa place dans quatre situations: En cas de métastase unique, dans un but de réduction tumorale avant immunothérapie, elle peut être adjuvante après.

  1. Cuidados de enfermagem na prevenção da insuficiência renal provocada por contraste após cateterismo Cuidados de enfermagem na prevenção da insuficiência renal provocada por contraste após cateterismo Nursing care in the prevention of renal failure caused by post-catheterism contrast

    Directory of Open Access Journals (Sweden)

    Flavia Giron Camerini

    2008-01-01

    Full Text Available O estudo teve como objetivo identificar produções científicas de enfermagem sobre insuficiência renal aguda provocada por contraste iodado após cateterismo cardíaco, no período de 2002 a 2007, analisando sua aplicabilidade à prática. Foi realizada ainda uma análise crítica das produções científicas selecionadas, delineando os cuidados de enfermagem. Este estudo é uma pesquisa bibliográfica de artigos de enfermagem, encontrados através de busca computadorizada. Dos 47 artigos encontrados, 10 foram selecionados por terem atendido os critérios de inclusão. Após a análise dos artigos, verificamos a importância da atuação do enfermeiro na prevenção da insuficiência renal aguda provocada por contraste. Além disso, evidenciamos a melhor prática de enfermagem para a prevenção da insuficiência renal aguda provocada por contraste.El presente estudio tuvo como objetivo identificar producciones científicas de enfermería sobre la insuficiencia renal aguda provocada por contraste yodado después del cateterismo cardíaco, en el período de 2002 a 2007, analizando su aplicabilidad a la práctica. Se realizó además el análisis crítico de las producciones científicas seleccionadas, delineando los cuidados de enfermería. Este estudio es una investigación bibliográfica de artículos de enfermería, encontrados por medio de búsqueda computarizada. De los 47 artículos encontrados, 10 fueron seleccionados por haber atendido a los criterios de inclusión. Después del análisis de los artículos, verificamos la importancia de la actuación del enfermero en la prevención de la insuficiencia renal aguda provocada por contraste. Además de lo referido, evidenciamos una mejor práctica de enfermería para la prevención de la insuficiencia renal aguda provocada por contraste.The purpose of this study was to identify the nursing scientific production on acute renal failure caused by post-catheterism iodized cardiac contrast

  2. Caracterización de tejidos renales en adultos mediante espectroscopia por resonancia magnética h1

    OpenAIRE

    Rincón Mosquera, Nubia

    2012-01-01

    En la actualidad el cáncer renal es la segunda causa de mortalidad en la clasificación de los cánceres urológicos. En este tipo de tumores la forma de diagnosticarlo es a través de tomografía axial computarizada (TAC), ultrasonido, urografía excretora, arteriografía y resonancia magnética (RM). La imagen por resonancia magnética de los riñones tiene un gran potencial para conseguir resolución anatómica adecuada, capacidad de discriminación tisular y demostración del flujo sanguíneo. La RM es ...

  3. Hidrocolpo por ectopia ureteral em hemivagina associado a displasia renal: relato de caso e revisão da literatura Congenital hydrocolpos due to ectopic ureter in hemivagina associated with renal dysplasia: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Mario Flores Barba

    2004-04-01

    Full Text Available Os autores apresentam um caso de displasia renal associada a ectopia ureteral vaginal homolateral, com uretero-hidronefrose contralateral devida a compressão por hidrocolpo causado pela ectopia e por um septo vaginal oblíquo. Os exames de imagem utilizados foram urografia excretora, cistografia, ultra-sonografia, tomografia computadorizada e cintilografia renal com Tc-99m-DMSA. Foi realizada revisão da literatura sobre casos de hidrocolpo associado a malformações urinárias.The authors report a case of congenital hydrocolpos due to vaginal malformation (vaginal septae associated with ectopic ureter and renal displasia. Several imaging diagnostic procedures (ultrasonography, nuclear medicine, intravenous urography and computed tomography were performed. A review of the literature on hydrocolpos and its association with urinary malformations is also presented.

  4. Insuficiências respiratória e renal desencadeadas por miopatia metabólica por acúmulo de lipídios: relato de caso Respiratory and renal dysfunctions due to lipid storage metabolic myopathy: case report

    Directory of Open Access Journals (Sweden)

    Walther de Oliveira Campos Filho

    2002-09-01

    Full Text Available Relatamos o caso de um paciente de 26 anos que apresentou quadro clínico de rabdomiólise e mioglobinúria associadas a insuficiência renal e respiratória, três dias após o início de infecção de vias aéreas superiores. Os dados clínicos e laboratoriais, eletroneuromiografia e biópsia muscular conduziram ao diagnóstico de miopatia metabólica por deficiência enzimática relacionada ao metabolismo dos ácidos graxos. O paciente evoluiu favoravelmente com a instituição de suporte avançado de vida, incluindo assistência ventilatória e terapia dialítica, adequação dietética e reposição de L-carnitina. Discorremos sobre as diversas miopatias metabólicas, o diagnóstico, o diagnóstico diferencial e o tratamento.We report a case of a 26-years old male patient with rhabdomyolisis with myoglobinuria associated with acute renal and respiratory failure, that occurred three days after upper airway infection. In the clinical and laboratory investigation of the patient, including electromyography and muscular biopsy, the diagnostic lead to a metabolic myopathy due to an enzymatic deficiency related to a disorder of lipid metabolism. The patient improved successfully with institution of advanced life support, including ventilatory assistence, dialysis, dietary adjust and L-carnitine reposition.

  5. Diseño e implementación de un sistema domótico de radiofrecuencia para brindar gestión de networking, seguridad y confort usando los protocolos z-wave y zigbee

    OpenAIRE

    Intriago Velasquez, Gabriel Andres

    2015-01-01

    El presente proyecto desarrolla e implementa un sistema domótico de radiofrecuencia. De manera general, se escogió la domótica de radiofrecuencia, ya que es menos costosa y más fácil de implementar que la domótica cableada, a parte, que en los últimos años ha ganado confiabilidad de operación y comunicación entre sus dispositivos. Los protocolos de radiofrecuencia usados en el sistema domótico fueron Z-Wave y Zigbee, debido a su bajo consumo de potencia, funcionamiento de red en modo de malla...

  6. Resección hepática asistida con radiofrecuencia bipolar: primeras experiencias con el Surtron SB

    Directory of Open Access Journals (Sweden)

    José Luis González González

    Full Text Available Las resecciones primarias y secundarias del hígado tienen como uno de sus mayores dilemas el sangrado transoperatorio. La introducción de los equipos de radiofrecuencia, en particular el Surtron SB, comienza a dar resultados alentadores. Se presentan las primeras 8 experiencias cubanas con resecciones menores y mayores realizadas con este equipo. Siete de estos pacientes tenían metástasis y uno un hepatocarcinoma. Se practicaron 2 resecciones regladas y 6 atípicas, durante las cuales no hubo complicaciones y solo un paciente necesitó transfusión sanguínea.

  7. Evolución clínica de los enfermos renales crónicos en tratamiento sustitutivo con infección por VIH

    OpenAIRE

    Ramón Saracho; Eduardo Martín Escobar; Jordi Comas Farnés; Emma Arcos; Auxiliadora Mazuecos Blanca; Miguel Ángel Gentil Govantes; Pablo Castro de la Nuez; Óscar Zurriaga; Manuel Ferrer Alamar; Encarnación Bouzas Caamaño; Teresa García Falcón; José Portolés Pérez; José A. Herrero Calvo; Carlos Chamorro Jambrina; Íñigo Moina Eguren

    2015-01-01

    Los pacientes con infección por el virus de la inmunodeficiencia humana (VIH) y enfermedad renal que terminan en tratamiento sustitutivo renal constituyen un grupo especial con interés creciente para la nefrología. Con el objetivo de conocer datos epidemiológicos de los pacientes VHI+ en España, recogimos información individualizada durante los años 2004 a 2011 (periodo de uso de tratamiento antiviral de alta eficacia) en las comunidades autónomas (CCAA) de Andalucía, Aragón, Asturias, Catalu...

  8. Qué sabemos a partir de los estudios epidemiológicos sobre la exposición residencial a ondas de radiofrecuencia y su relación con el cáncer

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    Marina Pollán Santamaría

    2004-12-01

    Full Text Available En esta revisión se presentan y comentan los estudios existentes sobre la exposición residencial a campos de radiofrecuencia con relación a un posible aumento de incidencia o de mortalidad por cáncer. La mayor parte de estos estudios son de naturaleza ecológica, con una medida de exposición indirecta: la distancia a las antenas. El control de posibles factores de confusión más allá de la edad y el sexo es bastante limitado. Por estas razones, los resultados de estos estudios no tienen una fácil interpretación causal. Muchas veces el estudio fue motivado por la aparición de una agregación inusual de casos de cáncer. Algunos de estos clusters fueron reanalizados llegando a conclusiones diferentes, lo que demuestra la debilidad metodológica de este tipo de estudios.

  9. Tumoral response factors after radiofrequency ablation of hepatocellular carcinoma in cirrhotic liver Factores de respuesta tumoral tras ablación mediante radiofrecuencia del carcinoma hepatocelular sobre cirrosis

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    J. Calleja Kempin

    2005-10-01

    Full Text Available Objective: hepatocellular carcinoma (HCC ablation by radiofrequency (RFA is a novel technique with a great variety of methods whose efficacy and predictive factors have not been completely studied. Some of the main predictive factors in this type of treatment are analyzed in the present study. Patients and methods: ninety-three patients with hepatocellular carcinoma over cirrhosis, and with no indication for surgical resection were treated by RFA. Two different types of electrodes were used for RFA (refrigerated-"Cool-Tip" and perfusion with saline solution, the approach was percutaneous, by laparoscopy or laparotomy. Results: overall survival at 1, 2 and 3 years was 88, 81, and 76%, with a free-disease survival (FDS of 66, 31 and 17%, respectively. For tumors less than 3 cm, FDS at 1,2 and 3 years was 74, 44 and 30%, while for more than 3 cm in size FDS was 55, 12 and 0% (p = 0.02. FDS for HCC with one nodule was 70, 36 and 22%, and for more than one nodule it decreased to 50, 17 and 0% at 1, 2 and 3 years, respectively (p = 0.07. Surprisingly, the method employed for RFA has a main influence in FDS, with 0% at 3 years for perfusion electrodes and 26% for cool-tip electrodes at the same period. Conclusions: in this series, overall survival at three years was relatively high; however, tumoral size, number of nodules and RFS method were independent variables associated with disease-free survival.Objetivo: la ablación por radiofrecuencia del hepatocarcinoma (ARF es una técnica de reciente adquisición, cuya eficacia y factores predictivos no han sido suficientemente evaluados. El presente estudio fue diseñado para este análisis. Pacientes y métodos: se han tratado 93 pacientes con hepatocarcinoma sobre hígado cirrótico sin criterios de resección ni de trasplante hepático. El tratamiento se realizó mediante abordaje percutáneo, laparoscópico o mediante laparotomía con dos tipos de electrodos de radiofrecuencia, electrodo refrigerado y

  10. Costes de invalidez por insuficiencia renal crónica en la Delegación Baja California del Instituto Mexicano del Seguro Social

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    Bárbara Mayné Martinez-Marín

    Full Text Available Resumen Introducción: La Insuficiencia Renal Crónica (IRC es un problema de salud pública discapacitante que limita las capacidades funcionales y la calidad de vida de los pacientes, genera la pérdida de años de vida productiva, siendo factible obtener un dictamen de invalidez si no pueden desempeñar su actividad laboral, esto conlleva a incrementar costes por esta enfermedad en las instituciones de salud. Objetivo: Evaluar los costes de invalidez por Insuficiencia Renal Crónica en el Instituto Mexicano del Seguro Social (IMSS durante el año 2015 en la delegación Baja California (BC. Material y métodos: Estudio descriptivo y retrospectivo. Se realizó en la Delegación de BC del IMSS, se analizaron los expedientes de los asegurados con dictamen de invalidez por IRC en 2015, previa autorización por el Comité de Investigación, donde se evaluaron las variables de sexo, edad, años laborales perdidos, días de incapacidad temporal y costes por invalidez. Se realizó estadística descriptiva. Resultados: El total de pacientes estudiados fue de 81, donde el 83% fueron hombres y 17% mujeres, la edad promedio al momento del estado de invalidez fue de 46 años, con un promedio de años laborales perdidos de 19, se subsidiaron 7.842 días de Incapacidad Temporal para el Trabajo (ITT representando $1.125.759 millones de pesos con un coste de subsidio por invalidez de $3.008.104 millones de pesos, cantidades que sumadas representan el 3,37% del Producto Interno Bruto (PIB de Baja California. Conclusión: La enfermedad renal crónica produce altos costes monetarios y en especie en las instituciones de salud, por lo que prevenir enfermedades causantes y atención temprana, podrá mejorar la calidad de vida y disminuir el número de años laborales perdidos en esta enfermedad.

  11. Insuficiência renal aguda e febre prolongada – um caso de nefrite intersticial aguda induzida por fármacos

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    Melo, Cláudia; Santos Silva, Rita; Tomé, Soraia; Carvalho, Sónia; Teixeira, Paulo

    2013-01-01

    A nefrite intersticial aguda (NIA) é uma causa de insuficiência renal aguda em idade pediátrica. A etiologia medicamentosa é a mais frequente e o tratamento primário da NIA consiste na eliminação do agente etiológico suspeito. Descreve-se o caso de uma adolescente, de 15 anos, com uma síndrome febril com 24 dias de evolução, acompanhado de exantema maculopapular e insuficiência renal aguda (IRA). Após exclusão de etiologias mais frequentes, foi diagnosticada NIA induzida por fármacos e após d...

  12. Lesão renal aguda por glicerol: efeito antioxidante da Vitis vinifera L Acute kidney injury by glycerol: antioxidant effect of Vitis vinifera L

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    Elisabete Cristina de Oliveira Martim

    2007-09-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A lesão renal aguda (LRA é a complicação mais grave da rabdomiólise. Nessa síndrome, a liberação do pigmento heme desencadeia uma lesão que se caracteriza por vasoconstrição glomerular e toxicidade celular direta com provável componente oxidante. A renoproteção com antioxidantes tem demonstrado efeito satisfatório. As proantocianidinas são antioxidantes naturais encontradas no extrato da semente da uva. O objetivo deste estudo foi avaliar o efeito antioxidante da Vitis vinifera sobre a função renal de ratos submetidos à lesão induzida por rabdomiólise. MÉTODO: Foram utilizados ratos Wistar, machos e adultos pesando entre 250 e 300 g. A LRA foi induzida pela administração de glicerol 50% por via muscular. Os animais foram distribuídos em 4 grupos: grupo Salina (6 mL/kg de NaCl a 0,9%, por via intraperitoneal (dose única, Glicerol (6 mL/kg por via muscular metade da dose em cada região femoral, em dose única, grupo Vitis vinifera (3 mg/kg/dia, por via oral durante cinco dias e grupo Glicerol + Vitis vinifera que recebeu Vitis vinifera por cinco dias antes do glicerol. RESULTADOS: Foram avaliados a função renal (FR e o perfil oxidativo (peróxidos urinários FOX-2 e MDA-TBARS. O grupo glicerol de animais tratado com Vitis vinifera apresentou melhora da FR e redução dos níveis de peroxidação lipídica. CONCLUSÕES: Os resultados deste estudo confirmaram a ação antioxidante da Vitis vinifera na LRA induzida por glicerol.BACKGROUND AND OBJECTIVES: The Acute Kidney Injury (AKI is the most serious complication of rhabdomyolysis. In this syndrome, the delivery of heme pigment induces an injury that distinguishes itself by glomerular vasoconstriction and direct cellular toxicity with oxidative component. The renoprotection with antioxidants has demonstrated satisfactory effect. The proanthocyanidins are natural antioxidants found in the grape seed extract. The aim of this study was to

  13. Klotho urinario determinado por ELISA como biomarcador precoz de fracaso renal agudo en pacientes sometidos a cirugía cardiaca o angiografía coronaria

    OpenAIRE

    Torregrosa, Isidro; Montoliu, Carmina; Urios, Amparo; Giménez-Garzó, Carla; Tomás, Patricia; Solís, Miguel Ángel; Ramos, Carmen; Juan, Isabel; Puchades, María-Jesús; Saez, Guillermo T.; Blasco, María-Luisa; Miguel, Alfonso

    2015-01-01

    Introducción y objetivos: El fracaso renal agudo (FRA) es una complicación frecuente tras la cirugía cardiaca y las intervenciones percutáneas coronarias cuya aparición empeora el pronóstico de manera marcada. En los últimos años se han identificado nuevos biomarcadores precoces de FRA, pero aún quedan muchos aspectos importantes por resolver. Klotho es una proteína pleiotrópica que actúa como un factor paracrino y endocrino en múltiples órganos. En diversos modelos animales de FRA se ha demo...

  14. El fracaso renal agudo por mieloma múltiple: cuidados de los pacientes en una unidad de hemodiálisis

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    Víctor Cantín Lahoz

    2014-06-01

    Full Text Available El mieloma múltiple (MM es una neoplasia hematológica con proliferación anormal de inmunoglobulinas y sus cadenas en sangre. La insuficiencia renal es una complicación grave y frecuente que puede derivar en fracaso renal en el 20% de los casos y puede requerir de terapia renal sustitutiva. Al debutar con una clínica tan inespecífica es importante un diagnóstico y tratamiento precoz para evitar el daño renal ya que agrava las complicaciones y condiciona la supervivencia. La depuración sanguínea mediante técnicas extracorpóreas con filtros de alto poro o high cut-off (HCO son muy eficaces eliminando el 60-90% de las cadenas y recuperando la función renal en 50-80% de los casos. Debido a las características de estas sesiones prolongadas y la complejidad del tratamiento se requiere dedicación exclusiva por parte de enfermería durante todo el proceso. Métodos: 9 pacientes diagnosticados de MM con cifras de más de 500mg/dl de cadenas ligeras tratados con filtros HCO durante al menos 6 sesiones consecutivas de 6 horas de duración. Resultados: Se realizaron 107 sesiones y se recuperó la función renal en 7. Complicaciones: 18 problemas de flujo, 12 episodios de coagulación del circuito, 13 fiebre, 14 hipotensiones, 13 transfusiones, 5 tratamientos con ansiolítico y 7 recambios de catéter. Conclusiones: Las hemodiálisis de larga duración con filtros HCO son eficaces para eliminar las cadenas ligeras y recuperar la función renal. El papel de la enfermería es importante englobando una técnica compleja y dando una respuesta humana al debut de una enfermedad tan grave.

  15. Percepción de la calidad de vida referida por el paciente adulto con trasplante renal

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    María Isabel Durán Muñoz

    2014-03-01

    Full Text Available La percepción personal de un individuo de su situación de vida, dentro del contexto cultural y de valores en el que vive, y en relación con sus objetivos, expectativas, valores e intereses, se denomina, calidad de vida. Como en estudios de pacientes crónicos, los factores más influyentes en la percepción de la calidad de vida, se clasifican en: paciente, medicamento, enfermedad y calidad de la interacción entre paciente y sistema sanitario. Objetivos: Describir la percepción que tienen los pacientes sobre su calidad de vida, e identificar factores que influyen en esta percepción. Material y métodos: Estudio descriptivo transversal en pacientes adultos, con trasplante renal, que acuden a nuestra consulta hospitalaria y son autosuficientes en el tratamiento. Todos los pacientes han recibido charlas grupales sobre el manejo de su tratamiento antes del alta. Recogida de datos con cuestionario anónimo autoadministrado: Escala validada: cuestionario de salud SF-12 (versión 2, durante 4 meses. Se excluyeron pacientes que rechazaron participar y que necesitaban ayuda en el manejo del tratamiento. Se estimó un tamaño muestral de 222 pacientes. Variables dependientes: Calidad de vida. Variables independientes: Factores socio-demográficos, tipo inmunosupresores, educación sanitaria recibida por profesionales de la salud. Se solicitó consentimiento informado y se obtuvo informe favorable del Comité Ético de Investigación Clínica. Resultados: Participaron 209 pacientes. Edad media 55,2(±12,15 rango 21-80 años, siendo el 61,8 % hombres. El 42% eran jubilados, el 38,2% tenían estudios secundarios, el 71% convivían en pareja. El inmunosupresor más utilizado: Micofenolato de sodio (MYFORTIC® (65,5% y el 46,7% tomaban dos inmunosupresores. La información sanitaria sobre efectos secundarios la consideran insuficiente un 20,5%. La media de la percepción de la calidad de vida es de 44,72±8,11 para el componente físico y 47,47±8,8 para

  16. 159. Trombectomía de Vena Cava Inferior Por Invasión de Tumor Renal

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    N. Miranda

    2012-04-01

    Conclusiones: en casos seleccionados, el carcinoma de célula renal extendiéndose a VCI puede ser resecado sin dificultad sin necesidad de esternotomía, CBP o PCHP, constituyendo una alternativa curativa en el tratamiento de dichos tumores.

  17. EFECTO NEFROPROTECTOR DEL ÁCIDO ASCÓRBICO EN UN MODELO DE DAÑO RENAL INDUCIDO POR GENTAMICINA EN CONEJOS

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    Javier Antonio Padilla Funes

    2013-08-01

    Full Text Available Objetivo. Uno de los efectos secundarios mas notables de la Gentamicina es su nefrotoxicidad. En este estudio se propone el posible efecto nefroprotector del acido ascorbico como barredor de radicales libres de oxigeno. Metodología. Se ejecuto un estudio experimental en 24 conejos machos, raza Nueva Zelanda, cuyo peso fue de 1,5 +/- 0,5 Kg. Los sujetos experimentales fueron distribuidos en tres grupos. El grupo Control se manejo con Gentamicina a dosis de 80 mg/Kg/dia por via IM. El grupo Acido Ascorbico se trato a dosis de 200 mg/kg/dia via IP y Gentamicina 80mg/Kg/dia IM. El grupo Sham se manejo con SSN 0,9% por via IP e IM, durante cinco dias consecutivos, para cada grupo. Se determinaron los siguientes parametros: creatinina serica, N-Acetil s-D glucosaminidasa urinaria (NAG-U, diuresis e histopatologia de las muestras renales. Resultados. La creatinina serica fue significativamente mayor para el grupo Control respecto al grupo Acido Ascorbico (p<0,05. Respecto a la diuresis, se observo una tendencia a la poliuria en el grupo Control. En cuanto a NAG-U, se observo inhibicion completa de la actividad enzimatica en el grupo Acido Ascorbico. El analisis histopatologico demuestra hallazgos de necrosis tubular aguda en el 100% del grupo control, mientras que en el grupo Acido Ascorbico se obtuvo en un 50% de los sujetos unicamente detritos intraluminales. Conclusiones. La administracion concomitante de Acido Ascorbico con Gentamicina, disminuye significativamente el dano tubular renal, evidenciado en los valores de creatinina serica, NAG, diuresis e histopatologia renal.

  18. Lesión con radiofrecuencia percutánea en el manejo de la neuralgia trigeminal idiopática multitratada Injury with percutaneous radiofrenquency for the management of multitreated idiopa-thic trigeminal neuralgia

    OpenAIRE

    G. I. Picos; J. R. Hernández-Santos; S. Tenopala; J. C. Torres; M. Ramírez-Pérez

    2004-01-01

    Objetivo: Demostrar la eficacia de la radiofrecuencia percutánea en el manejo de la neuralgia trigeminal idiopática multitratada, así como un menor número de complicaciones con esta técnica. Material y métodos: Se incluyeron 10 pacientes con neuralgia trigeminal idiopática, con mala respuesta al tratamiento farmacológico convencional e intervencionista. Todos los procedimientos se realizaron bajo control fluoroscópico. Se realizó una lesión con radiofrecuencia a un rango de impedancia de entr...

  19. Programación temprana de alteraciones en el sistema del óxido nítrico renal y vascular inducidas por la deficiencia de cinc

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    María A. Costa

    2008-01-01

    Full Text Available Resumen:IntroducciónNumerosos estudios mostraron que la deficiencia nutricional durante la vida fetal y posnatal predisponen al desarrollo de patologías en la vida adulta, como la hipertensión arterial y las enfermedades renales. La distribución ubicua del cinc y sus propiedades químicas determinan su esencialidad en los sistemas biológicos.ObjetivosEvaluar si las alteraciones renales y cardiovasculares en la vida adulta inducidas por la restricción moderada de cinc durante la vida fetal, la lactancia y/o el crecimiento se asocian con cambios en el sistema del óxido nítrico.Material y métodosRatas Wistar hembra recibieron durante la preñez hasta el destete de las crías una dieta control o una baja en cinc. Luego del destete, las crías macho se asignaron al azar a dos grupos que recibieron una dieta control o una baja en cinc durante 60 días.ResultadosLos resultados mostraron que el aporte insuficiente de cinc durante el crecimiento previo y/o posterior al destete indujo un aumento de la presión arterial y una disminución del volumen de filtrado glomerular en la vida adulta, asociados con una disminución del sistema del óxido nítrico renal y vascular. Además, el bajo aporte de este mineral durante la vida fetal indujo un peso menor al nacer, que se correlacionó en forma negativa con la presión arterial en la vida adulta.ConclusionesEste trabajo brinda evidencias importantes que sugieren que el aporte inadecuado de cinc durante el crecimiento prenatal y posnatal constituye un factor de riesgo cardiovascular y renal, dado que induce alteraciones en la regulación de la presión arterial y en la función renal en el individuo adulto.REV ARGENT CARDIOL 2008;76:459-464.

  20. Estado redox en pacientes infectados por VIH/sida con insuficiencia renal crónica sometidos a hemodiálisis

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    Olga Castaño Araujo

    2012-12-01

    Full Text Available Introducción: el balance redox alterado en el curso de la insuficiencia renal crónica ha sido considerado un factor contribuyente a la morbilidad y mortalidad de la enfermedad y un factor asociado a la progresión de la infección por sida. Objetivo: valorar el estado redox en pacientes infectados por VIH con insuficiencia renal crónica que requirieron hemodiálisis. Métodos: se realizó un estudio de casos y controles en 20 pacientes VIH/sida con insuficiencia renal crónica y 40 individuos aparentemente sanos. Se realizaron determinaciones de malonildialdehído, glutatión, superóxido dismutasa, catalasa, productos avanzados de la oxidación de proteínas, hidroperóxidos y potencial de peroxidación, conjuntamente con los marcadores de progresión: conteo de linfocitos T CD4+ y carga viral y una serie de determinaciones hemoquímicas y hematológicas. El análisis se realizó antes, a los 30 min y a los 240 min del tratamiento dialítico. Estadísticamente se verificaron los supuestos de igualdad de varianza y normalidad de las variables, y en dependencia se aplicó una prueba paramétrica o no paramétrica. El resultado fue significativo para p< 0,05. Resultados: los indicadores del estado redox se encontraron alterados en los pacientes estudiados con respecto al grupo supuestamente sano antes de la hemodiálisis. Se mostró un valor mayor significativo (p< 0,05 de los índices malonildialdehído, productos avanzados de la oxidación de proteínas, superóxido dismutasa, y un valor menor de catalasa y glutatión a los 240 min de realizada la diálisis, con la excepción de los hidroperóxidos que no mostraron cambios. La carga viral plasmática disminuyó de manera significativa en el proceso. Conclusiones: los resultados sugieren que el proceso dialítico en este tipo de pacientes favorece el estrés oxidativo, conjuntamente con una disminución de la carga viral plasmática. El estudio aporta valor metodológico en el manejo de estos

  1. Estado redox en pacientes infectados por VIH/sida con insuficiencia renal crónica sometidos a hemodiálisis The redox state of VIH/AIDS patients suffering chronic renal failure and undergoing hemodyalisis

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    Olga Castaño Araujo

    2012-12-01

    Full Text Available Introducción: el balance redox alterado en el curso de la insuficiencia renal crónica ha sido considerado un factor contribuyente a la morbilidad y mortalidad de la enfermedad y un factor asociado a la progresión de la infección por sida. Objetivo: valorar el estado redox en pacientes infectados por VIH con insuficiencia renal crónica que requirieron hemodiálisis. Métodos: se realizó un estudio de casos y controles en 20 pacientes VIH/sida con insuficiencia renal crónica y 40 individuos aparentemente sanos. Se realizaron determinaciones de malonildialdehído, glutatión, superóxido dismutasa, catalasa, productos avanzados de la oxidación de proteínas, hidroperóxidos y potencial de peroxidación, conjuntamente con los marcadores de progresión: conteo de linfocitos T CD4+ y carga viral y una serie de determinaciones hemoquímicas y hematológicas. El análisis se realizó antes, a los 30 min y a los 240 min del tratamiento dialítico. Estadísticamente se verificaron los supuestos de igualdad de varianza y normalidad de las variables, y en dependencia se aplicó una prueba paramétrica o no paramétrica. El resultado fue significativo para pIntroduction: the altered redox balance in chronic renal failure has been considered a contributing factor to morbidity and mortality from this disease and as an AIDS progression-associated factor. Objective: to assess the redox state in HIV patients suffering chronic renal failure that requires haemodialysis. Methods: a case-control study was conducted in 20 HIV/AIDS patients with chronic renal failure and in 40 apparently healthy individuals. Estimations of malonildialdehyde, gluthatione, superoxide dismutase, catalase, advanced products from protein oxidation, hydroperoxides and peroxidation potentials, as well as progression markers such as T CD4+ lymphocyte count, viral load and a series of hemochemical and hematological determinations were all made. The analysis was made before, 30 minutes

  2. Cistatina C como predictor de síndrome cardio-renal y mal pronóstico en pacientes internados por insuficiencia cardíaca aguda y función renal normal

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    Iván Constantin

    2016-01-01

    Full Text Available Introducción: El desarrollo de disfunción renal en el contexto de una falla cardíaca aguda se conoce como síndrome cardiorrenal (SCR tipo 1. El empeoramiento de la función renal (EFR durante la internación es un predictor de mal pronóstico. La cistatina C ha surgido como un marcador de función renal alternativo a la creatinina. Objetivo: Demostrar la utilidad clínica de la cistatina C como predictor de EFR y factor pronóstico en pacientes con insuficiencia cardíaca aguda y sin disfunción renal evaluada por creatinina al ingreso. Material y métodos: Se llevó a cabo un estudio observacional, prospectivo, de pacientes consecutivos con diagnóstico de insuficiencia cardíaca aguda y sin disfunción renal, definida como un valor de creatinina < 1,3 mg/dl al ingreso. Se realizó un dosaje de cistatina C al ingreso. El punto final primario fue EFR y los secundarios fueron mortalidad hospitalaria, mortalidad total y reinternación por insuficiencia cardíaca. Resultados: Se incluyeron 166 pacientes con una mediana de edad de 85 años (IIC 77,7-89. La incidencia de EFR fue del 29,7%, con una mortalidad hospitalaria del 3,1% y una mortalidad total del 24,4%. La mediana de seguimiento fue de 193 días. El valor de cistatina C fue significativamente mayor en los pacientes que desarrollaron EFR (1,72 ± 0,58 mg/dl vs. 1,51 ± 0,41 mg/dl; p = 0,03 y en los pacientes que murieron en el seguimiento (1,76 ± 0,49 mg/dl vs. 1,51 ± 0,46 mg/dl; p = 0,004. La cistatina C resultó un predictor independiente de mortalidad (OR 3,03, IC 95% 1,22-7,47 y de EFR (OR 2,38, IC 95% 1,02- 5,5 en el análisis multivariado. Se halló un punto de corte óptimo de 1,6 mg/dl de cistatina, con una sensibilidad del 61,22% y una especificidad del 60,34% para el desarrollo de EFR y del 61,54% y 61,98%, respectivamente, para mortalidad total. Conclusión: El valor de cistatina C al ingreso es predictor de desarrollo de EFR durante la internación y de mayor mortalidad en

  3. Cistolitectomia e ressecção de cisto renal por laparoscopia em uma cadela com aderências intraperitoneais: relato de caso

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    J. Pigatto

    2011-08-01

    Full Text Available No presente relato descreve-se a remoção de urólitos vesicais, bem como o tratamento de um cisto renal por cirurgia laparoscópica em um cão com aderências intraperitoneais. Para o acesso foram utilizados três portais, dois de 10mm e um de 5mm, dispostos na linha média ventral e nas paredes abdominal direita e esquerda. Após a remoção das litíases, realizou-se sutura intracorpórea da parede vesical em duas camadas. O cisto renal direito foi drenado e sua cápsula extirpada. Ocorreu a perda temporária de um urólito na cavidade abdominal e sua posterior recuperação pela cirurgia laparoscópica. O paciente não apresentou recidiva da doença pelo período mínimo de 14 meses. A cirurgia laparoscópica mostrou-se eficaz na terapêutica de ambas as patologias, sem a necessidade de alteração do posicionamento dos portais.

  4. Infección por Polyoma virus en un paciente con transplante renal: A propósito de un caso

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    Reyner Loza Munarriz

    2008-07-01

    Full Text Available La nefropatia por polyoma virus (NVBK esta siendo reconocida como causa importante de falla del injerto, usualmente confundido con rechazo agudo. A la fecha, no se han reportado casos en el Perú. Se presenta el caso de un niño trasplantado, 17 años de edad, quien presentó elevación persistente de la creatinina sérica en el primer mes postrasplante. Fue tratado como rechazo agudo. Al no presentar mejoría se realizó biopsia renal que mostró marcado daño del epitelio tubular con necrosis parcial y desprendimiento hacia la luz tubular y la presencia de células atípicas con escaso citoplasma e inclusiones intranucleares basofilicas, hallazgos compatibles con infección por virus BK. No se evidenció signos de rechazo. Además, en el papanicolao de orina, se encontró Decoy cells. La carga viral de virus BK fue elevada en sangre y en orina. Se suspendió el tratamiento con mofetil micofenolato, se redujo la dosis de tacrolimus y se inició el tratamiento con leflunomide 40 mg/dia. Seis meses después la función renal del paciente se estabilizó, pero sin mejoría completa quedando con una depuración de creatinina de 30 ml/min/1,73 m² SC. (Rev Med Hered 2008;19:123-127

  5. La infección por citomegalovirus postrasplante renal y pérdida del injerto a largo plazo

    Directory of Open Access Journals (Sweden)

    María Ovidia López-Oliva

    2017-09-01

    Conclusión: La replicación viral después del trasplante es un factor de riesgo de pérdida del injerto pero no de mortalidad a largo plazo. Las estrategias de prevención disminuyen la incidencia de infección y enfermedad por CMV postrasplante.

  6. EFECTO NEFROPROTECTOR DEL ÁCIDO ASCÓRBICO EN UN MODELO DE DAÑO RENAL INDUCIDO POR GENTAMICINA EN CONEJOS

    Directory of Open Access Journals (Sweden)

    Javier Antonio Padilla Funes

    2012-01-01

    Full Text Available Objetivo. Uno de los efectos secundarios más notables de la Gentamicina es su nefrotoxicidad. En este estudio se propone el posible efecto nefroprotector del ácido ascórbico como barredor de radicales libres de oxígeno. Metodología. Se ejecutó un estudio experimental en 24 conejos machos, raza Nueva Zelanda, cuyo peso fue de 1,5 +/- 0,5 Kg. Los sujetos experimentales fueron distribuidos en tres grupos. El grupo Control se manejó con Gentamicina a dosis de 80 mg/Kg/día por vía IM. El grupo Ácido Ascórbico se trató a dosis de 200 mg/kg/día vía IP y Gentamicina 80mg/Kg/día IM. El grupo Sham se manejó con SSN 0,9% por vía IP e IM, durante cinco días consecutivos, para cada grupo. Se determinaron los siguientes parámetros: creatinina sérica, N-Acetil ß-D glucosaminidasa urinaria (NAG-U, diuresis e histopatología de las muestras renales. Resultados. La creatinina sérica fue significativamente mayor para el grupo Control respecto al grupo Ácido Ascór- bico (p<0,05. Respecto a la diuresis, se observó una tendencia a la poliuria en el grupo Control. En cuanto a NAG-U, se observó inhibición completa de la actividad enzimática en el grupo Ácido Ascórbico. El análisis histopatológico demuestra hallazgos de necrosis tubular aguda en el 100% del grupo control, mientras que en el grupo Ácido Ascórbico se obtuvo en un 50% de los sujetos únicamente detritos intraluminales. Conclusiones. La administración concomitante de Ácido Áscórbico con Gentamicina, disminuye significativamente el daño tubular renal, evidenciado en los valores de creatinina sérica, NAG, diuresis e histopatología renal.

  7. Lesão renal aguda induzida por contraste: importância dos critérios diagnósticos para estabelecer a prevalência e o prognóstico na unidade de terapia intensiva

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    Edmilson Leal Bastos de Moura

    2017-09-01

    Full Text Available RESUMO Objetivo: Estabelecer se há superioridade entre os critérios para predizer desfecho clínico desfavorável na lesão renal aguda e nefropatia induzidas por contraste. Métodos: Estudo retrospectivo conduzido em hospital terciário com 157 pacientes submetidos à infusão de contraste radiológico para fins propedêuticos. Resultados: Cumpriram os critérios para inclusão 147 pacientes. Aqueles que cumpriram os critérios de lesão renal aguda induzida por contraste (59 também cumpriram os critérios para nefropatia induzida por contraste (76; 44,3% dos pacientes cumpriram os critérios para o estadiamento pelo sistema KDIGO; 6,4% dos pacientes necessitaram utilizar terapia de substituição renal, e 10,7% dos pacientes morreram. Conclusão: O diagnóstico de nefropatia induzida por contraste foi o critério mais sensível para determinar a necessidade de terapia de substituição renal e óbito, enquanto o KDIGO demonstrou a maior especificidade; na população avaliada, não houve correlação entre o volume de contraste e a progressão para lesão renal induzida por contraste, nefropatia induzida por contraste, diálise de suporte ou óbito.

  8. Renal arteriography

    Science.gov (United States)

    Renal angiogram; Angiography - kidney; Renal angiography; Renal artery stenosis - arteriography ... an artery by a blood clot Renal artery stenosis Renal cell cancer Angiomyolipomas (noncancerous tumors of the ...

  9. Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR Genetic Polymorphisms on Tacrolimus Metabolism in Chinese Renal Transplant Recipients

    Science.gov (United States)

    Lin, Li; Jiang, Hai-Xia; Zhong, Ze-Yan; Li, Wei-Mo; Zhang, Yan-Jun; Zheng, Ping; Tan, Xu-Hui; Zhou, Lin

    2014-01-01

    Tacrolimus is a widely used immunosuppressive drug for preventing the rejection of solid organ transplants. The efficacy of tacrolimus shows considerable variability, which might be related to genetic variation among recipients. We conducted a retrospective study of 240 Chinese renal transplant recipients receiving tacrolimus as immunosuppressive drug. The retrospective data of all patients were collected for 40 days after transplantation. Seventeen SNPs of CYP3A5, CYP3A4, COMT, IL-10 and POR were identified by the SNaPshot assay. Tacrolimus blood concentrations were obtained on days 1–3, days 6–8 and days 12–14 after transplantation, as well as during the period of the predefined therapeutic concentration range. Kruskal–Wallis test was used to examine the effect of genetic variation on the tacrolimus concentration/dose ratio (C0/D) at different time points. Chi-square test was used to compare the proportions of patients who achieved the target C0 range in the different genotypic groups at weeks 1, 2, 3 and 4 after transplantation. After correction for multiple testing, there was a significant association of C0/D with CYP3A5*3, CYP3A4*1G and CYP3A4 rs4646437 T>C at different time points after transplantation. The proportion of patients in the IL-10 rs1800871-TT group who achieved the target C0 range was greater (p = 0.004) compared to the IL-10 rs1800871-CT and IL-10 rs1800871-CC groups at week 3 after transplantation. CYP3A5*3, CYP3A4 *1G, CYP3A4 rs4646437 T>C and IL-10 rs1800871 C>T might be potential polymorphisms affecting the interindividual variability in tacrolimus metabolism among Chinese renal transplant recipients. PMID:24465960

  10. ¿Pueden afectar las microondas pulsadas emitidas por las antenas de telefonía a los árboles y otros vegetales?

    OpenAIRE

    A. Balmori

    2004-01-01

    El despliegue de la telefonía sin cable, acontecido durante la última década en todo el mundo, ha elevado la contaminación electromagnética en el rango de las radiofrecuencias en varios órdenes de magnitud, sobre todo en los núcleos habitados. No se han previsto los efectos sobre los seres vivos especialmente sobre los que, por su inmovilidad o sedentarismo, o por su proximidad a las instalaciones, padecen una irradiación crónica de niveles elevados, que según algunos expertos en bio...

  11. TRANSFERENCIA DE PACIENTES CON TRASTORNOS DEL RITMO CARDÍACO PARA ABLACIÓN CON RADIOFRECUENCIA Y SU SEGUIMIENTO DURANTE CINCO AÑOS / Transfer of patients with heart rate disorders for radiofrequency ablation and a five-year follow-up

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    Arelys Falcón Hernández

    2013-01-01

    Full Text Available Resumen Introducción y objetivos: La posibilidad de localizar, con catéteres–electrodos, las estructuras que intervienen en las arritmias, propiciaron el ímpetu para el desarrollo de técnicas que tuvieran que ver con la destrucción selectiva del tejido cardíaco. Ello es posible mediante la ablación con catéter de radiofrecuencia. Estos procedimientos constituyen la opción terapéutica de primera elección para la mayoría de las arritmias cardíacas. El objetivo fue caracterizar clínicamente el pre y post procedimiento terapéutico a pacientes transferidos para ablación con radiofrecuencia. Método: Estudio descriptivo, prospectivo, en 26 pacientes con trastornos del ritmo cardíaco, enviados para ablación con radiofrecuencia, seguidos en consulta externa durante cinco años en el Servicio de Cardiología del Hospital "Dr. Gustavo Aldereguía Lima", Cienfuegos. Las variables estudiadas fueron: edad, sexo, tipo de arritmia clínica presentada, sustrato arritmogénico ablacionado, complicaciones, éxito inicial y recurrencias de la arritmia tratada. Resultados: La edad media de los pacientes fue de 40,9 ± 17,6 años, mayoritariamente mujeres (57,7 %. A los pacientes más jóvenes (edad media 38,6 ± 19,7 años se les trató una taquicardia por reentrada intranodal y a los de mayor edad (media 53,4 ± 23 años se les ablacionó de forma no selectiva el nodo aurículo–ventricular. La mitad de los pacientes presentaban una taquicardia ortodrómica de ahí que, el sustrato arritmogénico más tratado fue una vía accesoria (65,4 %. Ocurrieron dos complicaciones mayores (7,7 %, ninguna directamente relacionada con la aplicación de la energía de radiofrecuencia. En dos pacientes (9,1 % la arritmia clínica previamente tratada recurrió durante el primer año, ambos tenían vías accesorias derechas. Conclusiones: Fue factible transferir pacientes para ablación con radiofrecuencia debido a convenios de trabajo con dos centros

  12. Tratamiento quirúrgico curativo de la fibrilación atrial mediante técnica de ablación con radiofrecuencia monopolar irrigada: resultados a corto y mediano plazo Surgical treatment of atrial fibrillation through irrigated ablation with monopolar radiofrequency: results to short and midterm

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    Sergio Franco

    2007-02-01

    Full Text Available No existe una publicación colombiana con seguimiento a mediano plazo acerca del uso de esta técnica. Objetivo: evaluar el tratamiento quirúrgico de la fibrilación auricular a través de radiofrecuencia monopolar irrigada, mediante el seguimiento clínico, electrocardiográfico y ecocardiográfico a corto y mediano plazo. Métodos: entre septiembre de 2003 y octubre de 2005, se evaluaron de manera prospectiva, 70 pacientes con diagnóstico de fibrilación atrial y otra patología cardiaca que requería intervención quirúrgica. Se utilizó el sistema de ablación por radiofrecuencia monopolar Cardioblate® (Medtronic, Inc.. Los resultados se analizaron en un paquete estadístico SPSS versión 11,0. Resultados: se reclutaron 70 pacientes, 52% de género femenino y 48% masculino, con edad promedio de 54 años y fracción de expulsión preoperatoria del 47%. Se halló insuficiencia mitral (49% y estenosis mitral (26% como principales causas de cirugía cardiaca primaria. Se evaluaron 87% de los pacientes a 18 meses (3 y 25. Se logró la curación de la arritmia en el 88% de ellos. Las arritmias residuales en este grupo fueron fibrilación auricular (6% y flutter atrial (6%. El 80% de las arritmias post-operatorias se encuentran durante los primeros quince días de la cirugía; las más frecuentes fueron fibrilación atrial y flutter atrial. Se suspendió la anticoagulación y la medicación antiarrítmica en el 89% y 90% de los pacientes respectivamente. La técnica quirúrgica utilizada no generó complicaciones inherentes a la misma. Conclusión: esta investigación demostró que la técnica de ablación quirúrgica de la fibrilación auricular con radiofrecuencia monopolar irrigada, es fácilmente reproducible, altamente efectiva y segura para el paciente.There is not any publication about the use of this technique with midterm follow-up in Colombia. Objective: to evaluate the surgical treatment of atrial fibrillation with the use of

  13. Cambios en la presión sanguínea causados por falla renal aguda o crónica, en una población de mascotas caninas de Bogotá D.C. Colombia - Sanguine Pressure Changes Caused By Acute Or Chronic Renal Failure, In Canine Pets Population In Bogotá D.C. Colombia

    OpenAIRE

    Sánchez Klinge Marta Elena.

    2006-01-01

    .- La insuficiencia renal es señalada como la causa más importante de la hipertensión arterial, ( Ettinger & Feldman 1997). Debido a la hipertensión en insuficiencia renal, se debe medir la misma en todos los perros sospechosos. La determinación de la presión arterial, común en humanos, no lo es en veterinaria, debido a la disposición anatómica de los miembros y a la baja intensidad de los sonidos producidos por la onda de pulso. En la primera fase se emplearon 20 perros, a los cuales se les...

  14. Occurrence of parasitism by Dioctophyma renale in ring-tailed coatis (Nasua nasua of the Tiete Ecological Park, São Paulo, Brazil Ocorrência de parasitismo por Dioctophyma renale em quati (Nasua nasua do Parque Ecológico Tietê, São Paulo

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    Liliane Milanelo

    2009-12-01

    Full Text Available Dioctophymosis is a worldwide renal parasitosis caused by the Dioctophyma renale nematode, which results in progressive destruction of renal tissue. Aquatics annelids are considered the main intermediate hosts and the literature refers as permanent hosts of dogs, wild mammals and even humans. During procedures for population control of coatis (Nasua nasua in the Ecological Park of Tietê (PET, was noticed the presence of parasitosis by D. renale. From 68 animals, males and females, young and adults, submitted to exploratory laparotomy, 51 were positive for the presence of worms, 9 were found only in the right kidney. In 10 cases, in addition to right kidney parasitism, worms were also observed in the abdominal cavity. In 24 cases D. renale was found only in the abdominal cavity and in 8 animals the right kidney was reduced to a small rigid structure. The study showed that the preferred site for parasitism of the worm, considered erratic, was the abdominal cavity in 66.66% of the cases.A dioctofimose é uma parasitose renal causada pelo nematóide Dioctophyma renale conhecida por gerar a destruição progressiva do parênquima renal. Anelídeos de água doce são considerados os principais hospedeiros intermediários e a literatura refere como hospedeiros definitivos cães domésticos, mamíferos selvagens e até seres humanos. Durante procedimentos de controle populacional de quatis (Nasua nasua no Parque Ecológico do Tietê (PET, evidenciou-se a presença do parasitismo por D. renale. Sessenta e oito animais foram submetidos à laparotomia, machos e fêmeas, jovens e adultos, dos quais 51 foram positivos para presença do parasita. Em 9 animais o parasita esteve presente apenas no rim direito; em 10 animais D. renale parasitava o rim direito e a cavidade abdominal simultaneamente. Em outros 24 quatis o parasita foi encontrado apenas na cavidade abdominal e em 8 animais o rim direito foi reduzido apenas a uma pequena estrutura rígida. O estudo

  15. Endovascular repair of an aorto-iliac aneurysm succeeded by kidney transplantation Tratamento endovascular de aneurisma aorto-ilíaco sucedido por transplante renal

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    Marcelo Bellini Dalio

    2010-09-01

    Full Text Available We present the case of aorto-iliac aneurysm in a patient with chronic renal failure requiring dialysis who were treated with an endovascular stent graft and, later on, submitted to kidney transplantation. A 53-year-old male with renal failure requiring dialysis presented with an asymptomatic abdominal aorto-iliac aneurysm measuring 5.0cm of diameter. He was treated with endovascular repair technique, being used an endoprosthesis Excluder®. After four months, he was successfully submitted to kidney transplantation (dead donor, with anastomosis of the graft renal artery in the external iliac artery distal to the endoprosthesis. The magnetic resonance imaging, carried out 30 days after the procedure, showed a good positioning of the endoprosthesis and adequate perfusion of the renal graft. In the follow-up, the patient presented improvement of nitrogenous waste, good positioning of the endoprosthesis without migration or endoleak. The endovascular repair of aorto-iliac aneurysm in a patient with end-stage renal failure under hemodialysis treatment showed to be feasible, safe and efficient, as it did not prevent the success of the posterior kidney transplantation.Apresentamos o caso de aneurisma aortoilíaco em um paciente com insuficiência renal crônica dialítica tratado com uma endoprótese vascular, sendo, após, submetido a transplante renal. Um homem de 53 anos com insuficiência renal dialítica apresentava um aneurisma abdominal aortoilíaco assintomático com 5,0cm de diâmetro. Foi tratado com técnica endovascular com uma endoprótese Excluderâ. Após quatro meses, foi submetido a transplante renal (doador cadáver com sucesso, com anastomose da artéria renal do enxerto na artéria ilíaca externa distal à endoprótese. A ressonância magnética 30 dias após o procedimento mostrou a endoprótese bem posicionada e o enxerto renal bem perfundido. No seguimento, o paciente evoluiu com melhora das escórias nitrogenadas, bom

  16. Tratamento endovascular de aneurisma da artéria renal por embolização com micromolas preservando o fluxo sangüíneo renal: relato de caso Endovascular treatment of renal artery aneurysm using microcoil embolization and renal blood flow preservation: case report

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    Marco Aurélio Cardozo

    2007-06-01

    Full Text Available O tratamento endovascular da doença aneurismática da artéria renal tem sido, cada vez mais, aceito como uma alternativa à cirurgia convencional, especialmente em casos de aneurismas complexos intra-parenquimatosos ou que comprometam a bifurcação da artéria renal. Os autores relatam a experiência do tratamento endovascular de uma paciente com aneurisma sacular da bifurcação da artéria renal direita, associado à hipertensão renovascular de difícil controle. Foi realizada a cateterização seletiva da artéria renal, com a inserção de micromolas no saco aneurismático. O aneurisma foi completamente ocluído com preservação total do fluxo sanguíneo renal. A evolução clínica foi satisfatória com redução significativa das medicações anti-hipertensivas. A angio-tomografia de controle, após o oitavo mês do procedimento, confirmou o sucesso do tratamento.Endovascular treatment of renal artery aneurysmal disease has been increasingly accepted as an alternative to conventional surgery, especially in cases of renal artery bifurcation or complex intrarenal aneurysms. The authors report a case of endovascular treatment of a saccular aneurysm of the right renal artery bifurcation associated with poorly controlled renovascular hypertension. Selective catheterization of the renal artery was performed and microcoils were inserted into the aneurysmal sac. The aneurysm was completely obliterated with total preservation of renal blood flow. Clinical evolution was satisfactory with significant reduction in anti-hypertensive drugs. Control tomographic angiography, after eight months, confirmed treatment success.

  17. O indivíduo renal crônico e as demandas de atenção Personas con enfermedad renal cronica y las demandas por atención The person with renal chronic disease and caring demands

    Directory of Open Access Journals (Sweden)

    Carla Klava dos Reis

    2008-06-01

    Full Text Available Objetivou-se analisar as diferentes fontes de demanda de atenção vivenciadas por oito mulheres com insuficiência renal crônica, em tratamento hemodialítico de um hospital universitário do interior do Estado de São Paulo. Trata-se de um estudo qualitativo, por meio de uma entrevista semi-estruturada. A análise foi descritiva por meio da técnica de análise de conteúdo. Dentre as demandas destacam-se: ausência de perspectiva quanto ao futuro; morte como possibilidade iminente; perda de autonomia e relação de dependência com a máquina. Há ainda a responsabilidade materna e a preocupação com o colega que vivencia tal problema. Tais demandas podem dificultar para a pessoa em direcionar atenção para situações importantes, como o tratamento e a busca por uma melhor qualidade de vida.El objetivo es analizar las fuentes de demanda de atención vividas por ocho mujeres con insuficiencia renal crónica, en hemodiálisis en un hospital universitario de una ciudad de São Paulo. Es un estudio cualitativo donde fueron realizadas entrevistas semi estructuradas. El análisis fue descriptivo a través de la técnica de análisis de contenido. Entre las demandas se destacan: ausencia de perspectivas con relación al futuro; muerte como posibilidad inminente; pérdida de autonomía y la situación de dependencia con la máquina; la responsabilidad materna y la preocupación con el colega que vive problema similar. Estas demandas pueden dificultar para la persona en dirigir la atención para situaciones importantes, tales como el tratamiento y la búsqueda por una mejor calidad de vida.The objective was to analyse the sources of attentional demands experienced by eight women with renal chronic disease undergone to hemodialisys treatment in a university hospital at the State of São Paulo. This is a qualitative study achieved by means of a semi-structured interview. The analysis was based on a content analysis technique. Among the demands the

  18. Denervação Renal com Cateter de Ablação por Radiofrequência de Ponta Irrigada em Hipertensos Resistentes

    OpenAIRE

    Staico, Rodolfo; Armaganijan, Luciana; Moreira, Dalmo; Sousa,Marcio; Borelli,Flavio; Amodeo, Celso; Melo Neto,Jônatas; Sousa, J Eduardo; Sousa,Amanda; Abizaid, Alexandre

    2014-01-01

    Introdução: Resultados de 3 anos do Symplicity HTN-1 mostraram superioridade da denervação simpática renal percutânea comparada à terapia medicamentosa em hipertensos resistentes. Entretanto, os desfechos de eficácia da denervação simpática renal percutânea no Symplicity HTN-3, primeiro ensaio controlado com procedimento simulado, não foram a...

  19. Magnetic resonance angiography in the evaluation of renal arteries: imaging findings; Angiografia por ressonancia magnetica na avaliacao das arterias renais: achados de imagem

    Energy Technology Data Exchange (ETDEWEB)

    Nacif, Marcelo Souto [Faculdade de Medicina de Teresopolis, RJ (Brazil). Curso de Radiologia]. E-mail: msnacif@yahoo.com.br; Santos, Alair Augusto Sarmet Moreira Damas dos [Instituto de Pos-graduacao Medica Carlos Chagas (VOT-Imagem), Rio de Janeiro, RJ (Brazil). Curso de Especializacao em Radiologia; Marchiori, Edson [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Dept. de Radiologia]. E-mail: msnacif@yahoo.com.br

    2006-07-15

    Objective: to describe indications, main findings and diagnosis of magnetic resonance angiographies of renal arteries. Materials and methods: a retrospective study including 56 imaging studies covering a total of 111 renal arteries, performed during the period between December 6, 2001 and March 11, 2004. The angiographies were performed in a 1.5 T scanner, in compliance with the Department protocol. Results: as regards sex, it was found that 55.4% (n = 31) patients were male and 44.6% (n = 25) were female. The youngest patient was 12 years old and the oldest 88 years old. From a total of 25 different clinical indications, systemic arterial hypertension was the principal one with 26.7% (n = 15), followed by abdominal and/or lumbar pain with 12.5% (n 7), abdominal aortic aneurysm with 10.7% (n = 6), renal artery stenosis with 8.9% (n = 5), and others. Among these 56 studies, 43 (76.7%) had different types of findings and 13 (23.2%) were normal. The majority of findings were related to vascular diameter and amongst them, parietal irregularities, aneurysms and stenosis were the most frequent. Parietal irregularity was the most frequent alteration in the right renal artery with 17.87% (n = 10) and stenosis, in the left renal artery, with 25.45% (n = 14). Conclusion: magnetic resonance angiography has shown to be an excellent non-invasive method for evaluation of renal arteries, because of its sensitivity and multiplanar capacity for demonstrating vascular structures. (author)

  20. What we know from epidemiological studies on cancer and residential exposure to radiofrequency fields Qué sabemos a partir de los estudios epidemiológicos sobre la exposición residencial a ondas de radiofrecuencia y su relación con el cáncer

    Directory of Open Access Journals (Sweden)

    Marina Pollán Santamaría

    2004-12-01

    Full Text Available This review discusses epidemiological studies on residential exposure to radiofrequency fields and its possible association with cancer are commented. Most of these studies are ecologic. They use the distance to the power station as a surrogated measure of exposure. Possible confounders other than sex and age are rarely considered. For these reasons, it is difficult to infer causality from their results. Very often the study was a carried out due to the observation of cluster of cancer cases. Some of these clusters were reanalysed yielding different conclusions, showing their methodological weakness.En esta revisión se presentan y comentan los estudios existentes sobre la exposición residencial a campos de radiofrecuencia con relación a un posible aumento de incidencia o de mortalidad por cáncer. La mayor parte de estos estudios son de naturaleza ecológica, con una medida de exposición indirecta: la distancia a las antenas. El control de posibles factores de confusión más allá de la edad y el sexo es bastante limitado. Por estas razones, los resultados de estos estudios no tienen una fácil interpretación causal. Muchas veces el estudio fue motivado por la aparición de una agregación inusual de casos de cáncer. Algunos de estos clusters fueron reanalizados llegando a conclusiones diferentes, lo que demuestra la debilidad metodológica de este tipo de estudios.

  1. Aleteo auricular postrasplante cardíaco tratado exitosamente mediante ablación por catéter

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    Carlos López

    2009-01-01

    Full Text Available RESUMENEl desarrollo de arritmias supraventriculares es un hallazgo frecuente en el seguimiento depacientes sometidos a trasplante cardíaco. La ablación por radiofrecuencia del aleteo auricularha demostrado que es el tratamiento de elección en pacientes con cardiopatía subyacentey sin ella, en tanto que son escasas las comunicaciones en la bibliografía acerca de sueficacia postrasplante cardíaco.En esta presentación se describe el caso de un paciente de 26 años con antecedente detrasplante cardíaco que presentó aleteo auricular en la evolución. En el estudio electrofisiológico se observó un aleteo auricular típico antihorario dependiente del istmo en laaurícula derecha del donante. La aurícula derecha del receptor se encontraba disociada, enritmo sinusal. Durante la aplicación de radiofrecuencia en el istmo a la altura de la línea desutura auriculoauricular derecha se observó la interrupción del aleteo. Ambas aurículasderechas quedaron en ritmo sinusal, disociadas por bloqueo bidireccional a nivel de la anastomosis.REV ARGENT CARDIOL 2009;77:408-410.

  2. Incidencia de insuficiencia renal aguda en niños hospitalizados por quemaduras en el Hospital Universitario San Vicente de Paúl de Medellín, 2007-2008

    Directory of Open Access Journals (Sweden)

    José William Cornejo Ochoa

    2008-11-01

    Full Text Available INTRODUCCIÓN: las quemaduras en niños se han identificado como causa principal de trauma y su asociación con insuficiencia renal aguda es una de las complicaciones más temidas debido a su alta tasa de mortalidad. OBJETIVO: establecer la incidencia de insuficiencia renal aguda y describir algunos de los factores asociados en niños quemados menores de 18 años atendidos en el Hospital Universitario San Vicente de Paúl de Medellín. MATERIALES Y MÉTODOS: estudio de cohorte prospectivo y descriptivo en pacientes menores de 18 años con quemaduras superiores al 30% de la superficie corporal total que ingresaron al Servicio de quemados del Hospital Universitario San Vicente de Paúl entre abril del 2007 y febrero 2008. RESULTADOS: en total se incluyeron 25 pacientes en el estudio y de acuerdo con los criterios utilizados el 64% desarrollaron insuficiencia renal aguda y presentaron una tasa de mortalidad del 12,5% mientras que en el grupo sin insuficiencia renal aguda no se presentaron muertes. No se encontraron diferencias significativas entre los dos grupos en ninguna de las variables, lo que podría deberse al tamaño de la muestra; sin embargo, la lesión por inhalación se vislumbra como un factor importante de riesgo. CONCLUSIONES: la insuficiencia renal aguda en pacientes quemados es una complicación muy frecuente y se la debe buscar activamente y hacerles un seguimiento estrecho a los pacientes. Hacen falta más estudios en Medellín para determinar los factores de riesgo asociados a esta complicación.

  3. Prospective study of fetal hydronephrosis diagnosed by ultrasound- contribution to prevent renal damage in childhood; Estudo prospectivo da hidronefrose fetal diagnosticada por ultra-som: uma contribuicao na prevencao ao dano renal na infancia

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Eduardo A.; Cabral, Antonio Carlos V.; Leite, Henrique V.; Filgueiras, Teresa F.; Oliveira, Raquel B.B.; Vilasboas, Aranai S.; Tiburcio, Arthur E.L.; Diniz, Jose Silveiro S. [Minas Gerais Univ., Belo Horizonte, MG (Brazil). Hospital de Clinicas

    1998-03-01

    Newborns with anomalies of the urinary tract detected by fetal echography were investigated. The purpose was to identify prevalent uropathies, clinical outcome and variables of prognostic significance in patients with fetal hydronephrosis. The patients were investigated by ultrasound, micturating cystourethrography and radionuclide imaging, after beginning of chemoprophylaxis. Renal function and urinary tract infection were also studied. Eight-three patients were included in this study, 54(65,1%) of these were boys. Postnatal predominant diagnosis were pelviureteric junction obstruction (3,3%) and multicytic kidney (15,7%). Follow-up average was 35 {+-} 2.5 months. Renal function deteriored in 8 children during follow-up. Worse prognosis was associated with prenatal diagnosis before third trimester of gestation, bilateral uropathy, oligohydrammios, abnormal palpable kidney or bladder, abnormal renal function on admission and urethral obstruction. (author) 40 refs., 3 figs.

  4. Uso da radiofrequência bipolar para o tratamento da fibrilação atrial durante cirurgia cardíaca Uso de la radiofrecuencia bipolar para el tratamiento de la fibrilación atrial durante cirugía cardíaca Use of bipolar radiofrequency for the treatment of atrial fibrillation during cardiac surgery

    Directory of Open Access Journals (Sweden)

    Leonardo Secchin Canale

    2011-06-01

    Full Text Available FUNDAMENTO: O tratamento da fibrilação atrial com dispositivo de ablação de tecidos por radiofrequência bipolar em concomitância à cirurgia cardíaca tem se mostrado método eficaz no tratamento desta arritmia. OBJETIVO: Descrever a experiência inicial do Instituto Nacional de Cardiologia no tratamento cirúrgico da fibrilação atrial com uso de dispositivo de radiofrequência bipolar em pacientes submetidos à cirurgia cardíaca, relatando o resultado de acompanhamento pós-operatório de um ano. MÉTODOS: Entre janeiro de 2008 e março de 2009, 47 pacientes (36 mulheres consecutivos, com idade média de 53,7 ± 10,6 anos, apresentando fibrilação atrial por um período médio de 34,6 meses (3 a 192 meses foram submetidos à ablação cirúrgica desta arritmia, por radiofrequência bipolar, durante o procedimento que motivou a indicação da cirurgia. Oito apresentavam fibrilação atrial intermitente e 39, contínua. Oitenta e um por cento foram submetidos à cirurgia valvar como procedimento principal. Esta é uma análise retrospectiva, observacional, com avaliação de um ano de pós-operatório das variáveis clínicas e de Holter 24 h. RESULTADOS: Dos 47 pacientes, 40 sobreviveram um ano. Desses, 33 foram submetidos a Holter 24 h, em um intervalo médio de 401 dias após a cirurgia. Encontrou-se a seguinte distribuição de ritmos: 24 (73% sinusal, 5 (15% fibrilação atrial, três (9% Flutter atrial e um (3% ritmo juncional. Foram observados dois acidentes vasculares encefálicos, sendo um associado à arritmia supraventricular. CONCLUSÃO: A ablação cirúrgica de fibrilação atrial com dispositivo de radiofrequência bipolar concomitante à cirurgia cardíaca é método eficaz para o tratamento desta arritmia.FUNDAMENTO: El tratamiento de la fibrilación atrial con dispositivo de ablación de tejidos por radiofrecuencia bipolar en concomitancia con la cirugía cardíaca se muestra un método eficaz en el tratamiento de esta

  5. Láser, luz pulsada, radiofrecuencia y otras fuentes de energía: ¿complemento ocasional a la Cirugía Plástica?

    Directory of Open Access Journals (Sweden)

    R. García Pumarino Santofimia

    Full Text Available Las consultas de Cirugía Plástica se están llenando de pacientes con expectativas crecientes acerca de los resultados de los tratamientos con distintas fuentes de energía. El objetivo es conseguir un elevado índice de beneficio cosmético en el mínimo número de sesiones y con un tiempo breve de recuperación. Los tres elementos sobre los que podemos trabajar son el soporte, la textura y las alteraciones pigmentarias de la piel. Los sistemas de luz y de radiofrecuencia permiten combinar distintos niveles de tratamiento, como son la dermis profunda, la dermis papilar y la epidermis y constituyen un complemento a los procedimientos quirúrgicos, aportando un concepto "biológico" al estimular la regeneración y la neocolagenogénesis. En este artículo se describen los fundamentos de estos tratamientos complementarios que son de obligado conocimiento para los cirujanos plásticos.

  6. Valoración en un solo paso del potencial donante renal: Angiografía y urografía por RM con correlación quirúrgica One-step MR angiography and urography in the evaluation of potential renal living donors.

    OpenAIRE

    María Bolaño Vega; Eduardo Martín; Luis Mainetti; Olga Guardia; Diego Pineda Ordóñez; Ricardo Román

    2011-01-01

    Objetivos. Evaluar el rendimiento diagnóstico de la angiografía renal (ARM) y urografía (URM) por Resonancia Magnética (RM) en potenciales donantes de riñón mediante la correlación con hallazgos quirúrgicos. Materiales y Métodos. Se evaluaron 55 potenciales donantes mediante protocolo angiográfico y urográfico en múltiples fases en un resonador de 1,5 T. La ARM valoró la existencia de variantes anatómicas o alteraciones estructurales arteriales o venosas y la URM valoró el parénquima renal y ...

  7. Ablación por radiofrecuencia de vía anómala en paciente con agenesia de la vena cava inferior

    OpenAIRE

    Gómez, Carlos A.; Múñoz, Edison; Ramos, Luis F.

    2015-01-01

    Describimos un caso de una paciente de sexo femenino de 55 años de edad a quien se le diagnosticó síndrome de Wolff-Parkinson-White, y al ser llevada al procedimiento de ablación se le encuentra agenesia de la vena cava inferior, con continuidad hacia las cavidades cardiacas derechas a través de la vena ácigos. La realización posterior del procedimiento a través de dicha vena se consideró exitosa, pero ante la recurrencia de las alteraciones electrocardiográficas y nuevos episodios de taquica...

  8. SISTEMAS DE IDENTIFICACIÓN POR RADIOFRECUENCIA, CÓDIGO DE BARRAS Y SU RELACIÓN CON LA GESTIÓN DE LA CADENA DE SUMINISTRO

    National Research Council Canada - National Science Library

    ALEXANDER CORREA ESPINAL; CARLOS ESTEBAN ÁLVAREZ LÓPEZ; RODRIGO ANDRÉS GÓMEZ MONTOYA

    2010-01-01

    .... Para ello, se compilan conceptos generales de los sistemas de identificación presentando sus definiciones, componentes de hardware/software, aplicaciones en la cadena de suministro y el uso que grandes, medianas...

  9. Pre-surgical staging of renal cell carcinoma using imaging methods; Estadiamento pre-operatorio por imagem do carcinoma de celulas renais

    Energy Technology Data Exchange (ETDEWEB)

    Barroso, Vivian Alvim; Bauab Junior, Tufik [Instituto de Radiodiagnostico Rio Preto, Sao Jose do Rio Preto, SP (Brazil); Barroso Junior, Ubirajara [Universidade Federal de Sao Paulo (UNIFESP), SP (Brazil). Escola Paulista de Medicina. Div. de Urologia

    2000-04-01

    The incidental discovery of renal tumors has become more frequent lately. As a result, a more precise preoperative characterization of such tumors is necessary to allow the selection of the best treatment for each case, such as nepron-sparing surgery, radical nephrectomy, or immunotherapy. Computed tomography has been the most used imaging method to study these tumors. Large tumors, perinephric fat invasion, multicenter tumors, vascular invasion and stage IV are all computed tomography criteria which may exclude nephron-sparing surgery as a curative therapy. Furthermore there are some tomographic pitfalls in the detection of perinephric fat invasion and tumoral nodes. In this paper, the importance and accuracy of computed tomography for renal cancer staging is evaluated. (author)

  10. Intoxicação por carambola em paciente com insuficiência renal crônica: relato de caso Star fruit intoxication in a chronic renal failure patient: case report

    Directory of Open Access Journals (Sweden)

    Fábio Gonzaga Moreira

    2010-12-01

    Full Text Available A insuficiência renal crônica é doença de elevada morbidade e mortalidade e sua incidência e prevalência em estágio terminal têm aumentado progressivamente a cada ano. Segundo a Sociedade Brasileira de Nefrologia, as principais causas de insuficiência renal crônica são hipertensão arterial, glomerulonefrite e diabetes mellitus. Diversos fatores elevam o risco de mortalidade em pacientes com nefropatia crônica, principalmente idade, presença de diabetes e número de comorbidades associadas. Para pacientes com menos de 50 anos de idade a taxa de sobrevida em 5 anos é de 62% e para aqueles acima desta idade e com diagnóstico de diabetes mellitus a sobrevida é de apenas 23%. A carambola, fruta originária da Ásia e muito difundida na maioria dos países tropicais, tem sido reportada como contendo uma neurotoxina capaz de provocar graves alterações neurológicas em pacientes com histórico de nefropatia crônica. Dentre estas alterações podemos observar desde quadros leves, como soluços e confusão mental, até quadros mais sérios, como convulsões e morte. Essa neurotoxina parece apresentar especificamente inibição sobre o sistema de condução GABAérgico. Descrevemos o caso de um paciente nefropata crônico que, após ingestão de carambola, inicia quadro de mal-estar, náuseas e vômitos, seguidos de episódios convulsivos reentrantes e vai a óbito mesmo com o tratamento hemodialítico convencional.Chronic renal failure is a high morbidity and mortality condition, with its terminal phase incidence and prevalence steadily growing year after year. According to the Sociedade Brasileira de Nefrologia [Brazilian Society of Nephrology], the main causes of renal failure are arterial hypertension, glomerulonephritis and diabetes mellitus. Several factors are implied on chronic renal failure patients' risk of mortality, particularly age, diabetes and associated co-morbidities. For patients below 50 years old, the 5 years

  11. Efecto de los dispositivos de emisión de microondas, radiofrecuencia no ablativa y ultrasonido microfocalizado en el tratamiento de la hiperhidrosis primaria revisión sistemática de la literatura

    OpenAIRE

    Parra Ulloa, Diana Catalina; Cardona Olmos, Andrea del Pilar

    2016-01-01

    Antecedentes y objetivos: La hiperhidrosis primaria afecta el 2,8% de la población de Estados Unidos. Condición que impacta el desarrollo social de los individuos afectados, ocasionando fobia social. Existen opciones disponibles para el tratamiento de la hiperhidrosis incluyendo medicamentos tópico, sistémico, inyectable y quirúrgico. El objetivo de ésta revisión sistemática de la literatura es determinar la efectividad y seguridad de los dispositivos de emisión de microondas, radiofrecuencia...

  12. Valoración en un solo paso del potencial donante renal: Angiografía y urografía por RM con correlación quirúrgica One-step MR angiography and urography in the evaluation of potential renal living donors.

    Directory of Open Access Journals (Sweden)

    María Bolaño Vega

    2011-12-01

    Full Text Available Objetivos. Evaluar el rendimiento diagnóstico de la angiografía renal (ARM y urografía (URM por Resonancia Magnética (RM en potenciales donantes de riñón mediante la correlación con hallazgos quirúrgicos. Materiales y Métodos. Se evaluaron 55 potenciales donantes mediante protocolo angiográfico y urográfico en múltiples fases en un resonador de 1,5 T. La ARM valoró la existencia de variantes anatómicas o alteraciones estructurales arteriales o venosas y la URM valoró el parénquima renal y el sistema colector en fases nefrográfica y excretora. Los resultados fueron comparados con hallazgos quirúrgicos. Resultados. La correlación se realizó en 42 donantes efectivos. En ellos, se observó una especificidad de la ARM del 94% y una exactitud diagnóstica del 93%. Se identificaron variantes anatómicas y alteración estructural arterial en el 29% de los pacientes. La valoración venosa y urográfica de la RM resultó concordante quirúrgicamente en todos los casos. Conclusión. Las imágenes de RM proveen un método seguro y eficaz para la valoración prequirúrgica renal de forma integral en potenciales donantes de riñón.Objectives. To evaluate diagnostic accuracy of renal MRangiography(MRA and MR- urography (MRU in the assessment of normal anatomy and renal vascular pathology in potential renal living donors compared with surgical findings. Materials and Methods. Evaluation of 55 potential living donors performing one-step MR angiography and MR urography in a 1.5 T magnet. MRA evaluated the presence of anatomic variants or arterial or venous pathologic conditions. MRU depicted renal parenchyma anatomy and collector system. These results were compared with surgical findings. Results. MRA and MRU findings were actually compared with surgical findings in 42 effective donors. MRA specificity was 94 % and diagnostic accuracy was 93 %. Anatomic variants and arterial structural abnormalities were detected in 29 % of patients. Venous

  13. Supervivencia del injerto renal según la categoría de Banff 2013 en biopsia por indicación

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    Carlos Arias-Cabrales

    2016-11-01

    Conclusiones: La clasificación de Banff 2013 permite el diagnóstico histológico en el 95% de las biopsias por indicación. La categoría 6 es la más frecuente, pero se observa una modificación en la histopatología predominante según el tiempo postrasplante. Los cambios mediados por anticuerpos se asocian con peor supervivencia del injerto.

  14. Daño renal en ratas inducido por veneno de Bothrops neuwiedii diporus de Argentina Renal injury in rats poisoned by venom of Bothrops neuwiedii diporus from Argentina

    Directory of Open Access Journals (Sweden)

    Patricia Koscinczuk

    2004-08-01

    Full Text Available La insuficiencia renal aguda es una de las complicaciones sistémicas más frecuentes después de un accidente ofídico. En este estudio se evalúan los efectos que el veneno de Bothrops neuwiedii diporus produce en el riñón de ratas machos de la cepa Wistar. La histopatología permitió comprobar el desarrollo de necrosis tubular aguda; las lesiones iniciales se observaron a las 3 horas de la inoculación de una dosis de 700 µg del veneno, observándose en corteza renal congestión y degeneración granulohialina de las células epiteliales tubulares, acompañadas de dilatación y cilindros hialinos en la luz tubular. A las 24 horas se presentó necrosis tubular aguda en una superficie extensa de la corteza sin daño de la membrana basal tubular. Las lesiones de degeneración turbia de células epiteliales tubulares, dilatación de la luz tubular y cilindros hialinos se mantuvieron presentes hasta las 4 semanas post-inoculación. Si bien los parámetros de la bioquímica clínica asociados con insuficiencia renal aguda aumentaron a las 6 horas de la administración del veneno (urea: 1.10±0.22 g/dl; creatinina: 19.60±1.51mg/dl, a la semana descendieron a valores normales. Las densidades urinarias, en cambio, a la semana se mantuvieron más bajas que lo normal, 1.005 ± 0.001 (pAcute renal failure is one of the systemic complications that can be found in bothropic accidents. In this study the effects on male Wistar rats induced by the venom of Bothrops neuwiedii diporus were evaluated. The histopathology revealed acute tubular necrosis, lesions firstly were observed 3 hours post inoculation of 700 µg of venom. Cortical kidney congestion and granulohialin degeneration of tubular epithelial cells were observed, these lesions achieved a maximum at 24 hours after inoculation. Tubular epithelial hidropic degeneration and dilatation of tubular lumen with hyalin casts were present inclusive up to 4 weeks after inoculation. Biochemical parameter

  15. Litiasis coraliforme renal izquierda

    OpenAIRE

    Polo Barzallo, Humberto; Vintimilla Carzola, María Paz

    2014-01-01

    Introducción: El cálculo coraliforme se denomina de esta manera porque ocupan la mayor parte del sistema colector y se asemeja al coral marino, o a las astas de un venado. (1) Estos cálculos comprometen la función renal por un fenómeno obstructivo e infeccioso, patología que de no ser tratada efectivamente lleva al daño renal progresivo e irreversible. (2) Caso Clínico: Paciente de sexo masculino de 60 años de edad.Antecedentes: Litiasis Renal Izquierda con tratamiento quirúrgico a base...

  16. Cuidado em situação de Doença Renal Crônica: representações sociais elaboradas por adolescentes Atención en situación de Enfermedad Renal Crónica: representaciones sociales de adolescentes Care in situation of Severe Renal Insufficiency: social representations elaborated by adolescent

    Directory of Open Access Journals (Sweden)

    Islane Costa Ramos

    2008-04-01

    Full Text Available O objetivo do estudo foi apreender as representações sociais dos adolescentes em relação ao cuidado em situação de Insuficiência Renal Crônica. Aplicou-se o teste de associação livre de palavras a 70 adolescentes e a entrevista semi-estruturada a oito adolescentes. Foram evocadas 1630 palavras a partir dos estímulos doença, saúde, diálise, cuidado de si, cuidado profissional e cuidado familiar. Das entrevistas foram construídos dois núcleos temáticos que trazem significações sobre o cuidado familiar e o cuidado profissional que influenciam nas formas de perceber e agir em relação ao cuidado à saúde. Conclui-se que a representação social do adolescente focaliza as significações do adoecimento e do cuidado, marcada pela indissociabilidade entre as práticas de cuidado e as relações psico-afetivas e sociais imbrincadas na sua vivência.El estudio tuvo como objetivo aprehender las representaciones sociales de los adolescentes en relación a la atención en situación de Insuficiencia Renal Crónica. Se utilizó la prueba de asociación libre de palabras y la entrevista estructura en parte. Fueron 1.630 palabras a partir de los estímulos enfermedad, salud, dialisis, atención de si, atención profesional y atención familiar. De las entrevistas fueron construídos dos grupos de temas que tuvieron significaciones sobre la atención familiar y la atención profesional com influjos en las maneras de percibir y además agir en relación a la atención a la salud. La representación social del adolescente observa las significaciones del adoecimiento y de la atención, señalada, todavía, por la indisociabilidad entre las prácticas de atención y las relaciones psicoafectivas y sociales que hay en su vivencia.The objective of the study was to apprehend the social representations of teenagers in relation to care in situation of Severe Renal Insufficiency. It was applied the test of free association of words to 70 teenagers

  17. Renal Leiomyosarcoma

    OpenAIRE

    Pastora Beardo; Maria José Ledo; Jose Luis Ruiz Campos

    2013-01-01

    Leiomyosarcoma (LMS) is a rare malignant tumor of smooth muscle origin that generally stems from soft tissues and uterine tissue. Although, a small percentage of these may originate from the smooth muscle or vessel walls, most of which are of venous origin. Renal leiomyosarcomas may arise from the smooth muscle fibers of renal pelvis, renal capsule or renal vessels, last one is the most frequent. We report a case of renal LMS that could be originated in the renal capsule.

  18. Efeitos da intoxicação por lítio sobre a locomoção de ratos em um modelo animal de insuficiência renal aguda cirurgicamente induzido

    Directory of Open Access Journals (Sweden)

    Bittencourt José Augusto Ferreira

    2001-01-01

    Full Text Available INTRODUÇÃO: O lítio é um metal usado sob a forma de sal para tratamento de episódios agudos de mania e no controle profilático de desordens afetivas bipolares. Pacientes com algum grau de insuficiência renal podem rapidamente sofrer intoxicação por esse fármaco. Nosso objetivo foi verificar a influência da litemia na locomoção em um modelo animal cirurgicamente induzido de insuficiência renal aguda (IRA. MÉTODOS: Foram submetidos 61 ratos Wistar a tratamento com lítio por uma semana previamente a nefrectomia unilateral. Trinta ratos foram induzidos a IRA. Foi administrado lítio ou solução fisiológica aos ratos e após observada sua locomoção e concentração de creatinina sérica. Utilizou-se análise estatítica. RESULTADOS: A creatina apresentou-se elevada nos ratos com IRA. A locomoção foi menor nos ratos com IRA que receberam lítio, havendo relação inversa entre a litemia e a atividade locomotora. CONCLUSÕES: O modelo animal cirúrgico de IRA foi efetivo. Ratos insuficientes renais que receberam lítio apresentaram alterações locomotoras comparados aos demais. O aumento da litemia causa diminuição proporcional na locomoção dos ratos.

  19. TRANSPLANTE RENAL

    Directory of Open Access Journals (Sweden)

    Soraia Geraldo Rozza Lopes

    2014-01-01

    Full Text Available El objetivo del estudio fue comprender el significado de espera del trasplante renal para las mujeres en hemodiálisis. Se trata de un estudio cualitativo-interpretativo, realizado con 12 mujeres en hemodiálisis en Florianópolis. Los datos fueron recolectados a través de entrevistas en profundidad en el domicilio. Fue utilizado el software Etnografh 6.0 para la pre-codificación y posterior al análisis interpretativo emergieron dos categorías: “las sombras del momento actual”, que mostró que las dificultades iniciales de la enfermedad están presentes, pero las mujeres pueden hacer frente mejor a la enfermedad y el tratamiento. La segunda categoría, “la luz del trasplante renal”, muestra la esperanza impulsada por la entrada en la lista de espera para un trasplante.

  20. Carcinoma de células renales: estadificación prequirúrgica por tomografía computada y su analogía con la anatomía patológica Renal cell carcinoma: preoperative staging by computed tomography and its analogy to pathology

    Directory of Open Access Journals (Sweden)

    María Cinthya Ortega Hrescak

    2013-03-01

    Full Text Available Objetivo. Evaluar la correlación entre la estadificación preoperatoria de los carcinomas de células renales usando tomografía computada y los resultados anatomopatológicos de la pieza operatoria. Materiales y Métodos. Se llevó a cabo un estudio retrospectivo entre los años 2005 y 2011, tomando un total de 40 pacientes con diagnóstico presuntivo de carcinoma de células renales (CCR del Servicio de Urología, que habían sido sometidos a nefrectomía total o parcial. Se compararon diferentes parámetros del estudio imagenológico (tomografía computada y anatomopatológico de cada paciente y se evaluó qué reciprocidad existía entre la estadificación pre y posoperatoria según el TNM. Resultados. Los datos obtenidos mediante el estudio anatomopatológico de la pieza operatoria mostraron 28 lesiones limitadas al riñón (estadios T1 y T2, 3 lesiones con extensión perirrenal y a la vena renal (estadio T3a, 7 lesiones con compromiso de la vena cava (estadio T3b y 2 lesiones con extensión más allá de la fascia de Gerota (estadio T4. Se encontró una fuerza de concordancia casi perfecta entre la estadificación tomográfica y anatomopatológica (kappa = 0,87 con respecto al criterio T del TNM. Sólo 2 T1b (por estudio anatomopatológico fueron sobrediagnosticados como T2 (según tomografía computada y 2 T3b (según estudio anatomopatológico se subdiagnosticaron como T3a (según tomografía computada. Conclusión. La tomografía computada proporciona una buena delimitación y caracterización del carcinoma de células renales. El nivel de concordancia con el patrón de referencia más fiable (anatomía patológica resultó casi perfecto (k = 0,87 para la estadificación del estadio T.Objective. To evaluate the correlation between the preoperative staging of renal cell carcinoma by computed tomography (CT and histopathologic results of the surgical specimen. Materials and Methods. A retrospective study has been carried out in a total

  1. Renal leiomyosarcoma

    OpenAIRE

    Gelincik, İ; Tok, A

    2013-01-01

    Renal leiomyosarcomas are very rare and only account for 1-3% of primary renal malignancies. The prognosis for a renal sarcoma is poor, and differentiation from sarcomatoid renal cell carcinoma and a renal sarcoma is particularly necessary. The patient's clinical presentation and imaging findings are not helpful for accurate preoperative diagnosis. The primary treatment is radical nephrectomy with or without adjuvant radiotherapy chemotherapy. The prognosis is poor. We report a case of primar...

  2. Persistent hypertension and progressive renal injury induced by salt overload after short term nitric oxide inhibition Hipertensão persistente e lesão renal progressiva induzidas por sobrecarga de sal após inibição temporária do óxido nítrico

    Directory of Open Access Journals (Sweden)

    Ana Lúcia Mattar

    2007-01-01

    em sal (HS promove albuminúria e dano renal graves, reversíveis ao interromperem-se os tratamentos. OBJETIVO: Investigamos se tais alterações recrudescem ao reinstituir-se a HS e se são prevenidas pelo micofenolato mofetil (MMF, um agente antilinfócito, ou losartan, um bloqueador do receptor AT-1. MATERIAL E MÉTODOS: Ratos Münich-Wistar machos adultos receberam NAME e HS. Um grupo controle (C recebeu apenas HS. Após 20 dias, os ratos que receberam HS e NAME exibiam hipertensão e albuminúria graves. Após recuperação de 30 dias, a hipertensão atenuou-se e a albuminúria praticamente desapareceu. Formaram-se então os grupos: HS, recebendo HS; NS, recebendo dieta normal em sal (NS; HS-MMF, recebendo HS e MMF; HS-LOS, recebendo HS e losartan; HS-HDZ, recebendo HS e hidralazina. Após sessenta dias os ratos NS tinham albuminúria e dano/inflamação renal apenas discretos. Já os ratos HS desenvolveram hipertensão e glomerulosclerose acentuadas, expansão intersticial e infiltração renal por macrófagos e células positivas para angiotensina II. Losartan baixou a pressão arterial e preveniu albuminúria e lesão renal. MMF proporcionou proteção semelhante sem alteração pressórica, sugerindo a ação de mecanismos não hemodinâmicos, hipótese reforçada pelo achado de que a HDZ baixou a pressão arterial sem prevenir a nefropatia. RESULTADOS: Esses resultados indicam que o tratamento com HS e NAME predispõe ao desenvolvimento de hipertensão e lesão renal induzidos por excesso de sal, caracterizando um novo modelo de nefropatia crônica. CONCLUSÃO: A resposta ao MMF ou losartan, mas não à hidralazina, sugere o predomínio de fatores inflamatórios.

  3. Uso terapêutico da radiofrequência pulsátil no gânglio dorsal da raiz de L2 na lombalgia discogênica Uso terapéutico de la radiofrecuencia pulsátil en el ganglio dorsal de la raíz de L2 en la lumbalgia discogénica Pulsed radiofrequency on L2 dorsal root ganglion as a therapeutic method for lumbar discogenic pain

    Directory of Open Access Journals (Sweden)

    Fabrício Dias Assis

    2009-06-01

    Full Text Available OBJETIVO: Avaliar a eficácia da radiofrequência pulsátil sobre o gânglio da raiz dorsal de L2 no tratamento dos pacientes com lombalgia discogênica. MÉTODOS: Realizou-se análise retrospectiva de 50 pacientes portadores de lombalgia crônica discogênica atendidos no período de janeiro de 2004 a julho de 2007. O processo diagnóstico foi constituído por exame físico, ressonância magnética e bloqueio diagnóstico do gânglio da raiz dorsal de L2. Todos os pacientes foram submetidos à radiofrequência pulsátil no gânglio da raiz dorsal de L2 e acompanhados por, no mínimo, 12 meses. A intensidade de dor foi medida pela escala visual analógica (EVA de dor. RESULTADOS: A análise estatística mostrou melhora significativa da intensidade de dor (pOBJETIVO: evaluar la eficacia de la radiofrecuencia pulsátil sobre el ganglio de la raíz dorsal de L2 en el tratamiento de los pacientes con lumbalgia discogénica. MÉTODOS: fue realizado un análisis retrospectivo de 50 pacientes portadores de lumbalgia crónica discogénica, atendidos en el periodo de Enero de 2004 a Julio de 2007. El proceso diagnóstico constó de un examen físico, resonancia magnética y bloqueo diagnóstico del ganglio de la raíz dorsal de L2. Todos los pacientes fueron sometidos a la radiofrecuencia pulsátil en el ganglio de la raíz dorsal de L2 y seguidos por 12 meses, como mínimo. La intensidad del dolor fue medida por la escala visual analógica del dolor. RESULTADOS: el análisis estadístico mostró mejoría significativa de la intensidad del dolor (pOBJECTIVE: to evaluate the effectiveness of pulsate radio-frequency on L2 dorsal root ganglion for chronic discogenic low back pain. Of L2 in the treatment of the patient with discogenic low back pain. METHODS: Between January 2004 and July 2007, 50 patients with diagnosis of low back discogenic pain were retrospectively assessed based on physical examination, magnetic resonance imaging findings and selective L

  4. Colite por citomegalovirus em paciente transplantada renal: relato de caso e revisão da literatura Citomegalovirus colitis in kidney transplant patient: case report and literature review

    Directory of Open Access Journals (Sweden)

    Rogério Saad Hossne

    2007-06-01

    Full Text Available A infecção do citomegalovírus ocorre geralmente em pacientes imunocomprometidos sejam pós-transplantados ou pelas doenças que comprometem o sistema imune (AIDS; apresentamos um caso de um paciente do sexo feminino de 49 anos de idade, que se encontrava em pós-operatório tardio de transplante renal (14 anos, fazendo uso de medicações imunossupressoras. Evolui com quadro de dor abdominal, perda do peso e diarréia não sanguinolenta na fase inicial, necessitando de hospitalização, durante a qual desenvolveu severos quadros de hematoquezia e hipotensão. Submetida a colonoscopia que revelou mucosa de aspecto friável, com úlceras do tipo aftóides, fibrina e formação de pseudopólipos; a biopsia revelou tratar-se de citomegalovírus. Evolui sem melhora com o uso do foscarnet r, necessitando de tratamento cirúrgico, indo a óbito após 5 dias.Cytomegalovirus infection frequently develops in immunocompromised patients, either in post-transplanted patients or in patients with diseases that affects the immune system, such as AIDS; we present a case of a 49 year old female patient in late post surgery (14 years of a kidney transplant, using immunosuppressing medication. The patient presented abdominal pain, weight loss and initial diarrhea, she was hospitalized and developed severe hematochezia and hypotension. The patient was submitted to a colonoscopy and presented friable aspect mucosa, with aphthoid ulcers, fibrin and pseudopolyp formation; biopsy revealed cytomegalovirus. Her condition did not improve after the use of foscarnet, and surgical treatment was necessary. The patient died 5 days later.

  5. Renal Osteodystrophy

    Directory of Open Access Journals (Sweden)

    Aynur Metin Terzibaşoğlu

    2004-12-01

    Full Text Available Chronic renal insufficiency is a functional definition which is characterized by irreversible and progressive decreasing in renal functions. This impairment is in collaboration with glomeruler filtration rate and serum creatinine levels. Besides this, different grades of bone metabolism disorders develop in chronic renal insufficiency. Pathologic changes in bone tissue due to loss of renal paranchyme is interrelated with calcium, phosphorus vitamine-D and parathyroid hormone. Clinically we can see high turnover bone disease, low turnover bone disease, osteomalacia, osteosclerosis and osteoporosis in renal osteodystropy. In this article we aimed to review pathology of bone metabolism disorders due to chronic renal insufficiency, clinic aspects and treatment approaches briefly.

  6. Renal angiomyolipoma

    DEFF Research Database (Denmark)

    Holm-Nielsen, P; Sørensen, Flemming Brandt

    1988-01-01

    Renal angiomyolipoma is a rare lesion composed of smooth muscle cells, adipose tissue and abnormal vessels. It is currently classified as a benign, non-epithelial renal tumor. It has a high incidence in patients suffering from tuberous sclerosis but is more frequently found as an isolated renal...... lesion. Three cases of renal angiomyolipoma, 2 of which underwent perfusion-fixation, were studied by electron microscopy to clarify the cellular composition of this lesion. In the smooth muscle cells abundant accumulation of glycogen was found, whereas the lipocytes disclosed normal ultrastructural......-specific vesicular structures. These findings suggest a secondary vascular damage, i.e. the thickened vessels may not be a primary, integral part of renal angiomyolipoma. Evidence of a common precursor cell of renal angiomyolipoma was not disclosed. It is concluded that renal angiomyolipoma is a hamartoma composed...

  7. UNA PROPUESTA DIDÁCTICA PARA LA CARACTERIZACIÓN DE DISPOSITIVOS Y REDES ELÉCTRICAS DE RADIOFRECUENCIA EN LA BANDA DE 100 KHz A 500 MHz A DIDACTIC PROPOSAL FOR THE CHARACTERIZATION OF RADIO FREQUENCY DEVICES AND ELECTRICAL NETWORKS AT RANGE 100 KHz TO 500 MHz

    Directory of Open Access Journals (Sweden)

    R Linares y Miranda

    2010-12-01

    Full Text Available En este artículo se presenta un esquema didáctico de prueba y medición para la caracterización en el dominio de la frecuencia de componentes y circuitos lineales de radiofrecuencia (RF. El esquema se basa en la observación del comportamiento temporal manifestado por las tensiones incidentes y reflejadas. Éstas se pueden generar cuando se suministran señales sinusoidales de RF en los puertos o terminales de los dispositivos o redes eléctricas bajo estudio. El objetivo principal de este trabajo es el de proponer un método experimental alternativo que permita estudiar fenómenos que son abordados normalmente - a nivel licenciatura - en diversos programas de ingeniería eléctrica (o ramas afines. El método puede aplicarse en asignaturas donde se estudian tópicos vinculados al análisis de redes eléctricas. También en tópicos como la propagación de señales en líneas de transmisión, el diseño y operación de antenas y en los principios fundamentales de la compatibilidad electromagnética, entre otros.In this article a didactic outline of proof and measurement is presented for the characterization in frequency domain of components and linear circuits of radio frequency (RF. The outline is based on the observation of the temporary behavior shown by the incident and reflected tensions. These can be generated when RF sinusoidal signals are provided at ports and terminals of electrical networks or devices under study. The main goal of this paper is to propose an alternative experimental method that allows the study of phenomena normally addressed at the undergraduate level in various programs of Electrical Engineering or related disciplines. The method can be applied to subjects where topics related to the analysis of electrical networks are covered. It can also be applied to topics such as signal propagation in transmission lines, design and operation of antennas, and the fundamental principles of electromagnetic compatibility, among

  8. Occurrence of parasitism by Dioctophyma renale in ring-tailed coatis (Nasua nasua) of the Tiete Ecological Park, São Paulo, Brazil Ocorrência de parasitismo por Dioctophyma renale em quati (Nasua nasua) do Parque Ecológico Tietê, São Paulo

    OpenAIRE

    Liliane Milanelo; Márcia Bento Moreira; Fitorra,Lílian S.; Bruno S.S. Petri; Melissa Alves; Aparecida Cássia dos Santos

    2009-01-01

    Dioctophymosis is a worldwide renal parasitosis caused by the Dioctophyma renale nematode, which results in progressive destruction of renal tissue. Aquatics annelids are considered the main intermediate hosts and the literature refers as permanent hosts of dogs, wild mammals and even humans. During procedures for population control of coatis (Nasua nasua) in the Ecological Park of Tietê (PET), was noticed the presence of parasitosis by D. renale. From 68 animals, males and females, young and...

  9. Absceso renal en el embarazo

    OpenAIRE

    Goity F,Cecilia; Correa A,Eduardo; Daniels S,Paulina

    2012-01-01

    El absceso renal es una grave e infrecuente complicación de las infecciones del tracto urinario, siendo excepcional durante el embarazo. Su sintomatologia es inespecífica, por lo que el diagnóstico debe buscarse en forma activa. Se presenta un caso clínico de un absceso renal en una paciente cursando un embarazo gemelar, siendo tratada durante la gestación con buenos resultados.

  10. Study of amorphous films of TiAlN prepared by reactive cathodic erosion by radiofrequencies; Estudio de peliculas amorfas de TiAlN preparadas por erosion catodica reactiva por radiofrecuencias

    Energy Technology Data Exchange (ETDEWEB)

    Garcia G, L. [Programa de Posgrado en Materiales del Centro de Investigacion y de Estudios Avanzados del IPN, Unidad Queretaro, Libramiento Norponiente No. 2000, Fracc. Real de Juriquilla, 76230 Queretaro (Mexico); Morales H, J. [Programa de Posgrado en Ingenieria de la Facultad de Ingenieria de la Universidad Autonoma de Queretaro, (Mexico); Bartolo P, J.P.; Ceh S, O. [Centro de Investigacion y de Estudios Avanzados del IPN, Unidad Merida, Km. 6 Antigua Carretera a Progreso, A.P. 73 Cordemex 97310 Merida, Yucatan (Mexico); Munoz S, J.; Espinoza B, F.J. [Centro de Investigacion y de Estudios Avanzados del IPN, Unidad Queretaro, Libramiento Norponiente No. 2000, Fracc. Real de Juriquilla, 76230 Queretaro, (Mexico)

    2004-07-01

    Using the reactive magnetron r f sputtering technique, we prepared TiAlN films with amorphous structure on Corning glass and steel substrates in a reactive atmosphere of nitrogen and argon using a target of Ti-AI (40/60 wt. %). The average temperature of the substrates was about 25 C, with the purpose of obtaining amorphous films. The ratio of partial pressure of nitrogen to argon, PN/PAr was varied according to these values: 0.14, 0.28, and 0.43; fixing these values during whole the evaporation. Further on, films were prepared introducing nitrogen in periodic pulses with maximum values of PN/PAr 4.7 during 45 seconds, with fixed periods of 10, 15 and 20 minutes. In all cases amorphous films were obtained, according to X-ray Diffraction. The chemical composition of the samples was measured by electron dispersive spectroscopy, showing a clear dependence with the evaporation conditions. In spite of the amorphous structure of the material, atomic force microscopy measurements showed a surface morphology dependent on the nitrogen content. Additionally, measurements of electronic spectroscopy for chemical analysis and Raman scattering spectroscopy for identification of chemical bonds were carried out. Measurements of mechanical properties of the samples were carried out using nano indentation and micro-hardness Vickers's tests. (Author)

  11. Renal Afferents.

    Science.gov (United States)

    Frame, Alissa A; Carmichael, Casey Y; Wainford, Richard D

    2016-09-01

    The etiology of hypertension, a critical public health issue affecting one in three US adults, involves the integration of the actions of multiple organ systems, including the renal sympathetic nerves. The renal sympathetic nerves, which are comprised of both afferent (sensory input) and efferent (sympathetic outflow) arms, have emerged as a major potential therapeutic target to treat hypertension and disease states exhibiting excess renal sympathetic activity. This review highlights recent advances in both clinical and basic science that have provided new insight into the distribution, function, and reinnervation of the renal sympathetic nerves, with a focus on the renal afferent nerves, in hypertension and hypertension-evoked disease states including salt-sensitive hypertension, obesity-induced hypertension, and chronic kidney disease. Increased understanding of the differential role of the renal afferent versus efferent nerves in the pathophysiology of hypertension has the potential to identify novel targets and refine therapeutic interventions designed to treat hypertension.

  12. RENAL CRYOABLATION

    OpenAIRE

    A. V. Govorov; A. O. Vasilyev; D. Yu. Pushkar

    2014-01-01

    Renal cryoablation is an alternative minimally-invasive method of treatment for localized renal cell carcinoma. The main advantages of this methodology include visualization of the tumor and the forming of "ice ball" in real time, fewer complications compared with other methods of treatment of renal cell carcinoma, as well as the possibility of conducting cryotherapy in patients with concomitant pathology. Compared with other ablative technologies cryoablation has a low rate of repeat session...

  13. Celulitis por citomegalovirus

    Directory of Open Access Journals (Sweden)

    A. Ruiz Lascano

    2002-12-01

    Full Text Available Las lesiones cutáneas por citomegalovirus (CMV son infrecuentes y a menudo una manifestación tardía de una enfermedad sistémica, que generalmente anuncia un curso fatal. Comunicamos un caso de celulitis por CMV: una mujer de 70 años con trasplante renal efectuado 1 mes antes de la consulta, terapia inmunosupresora con ciclosporina A y metilprednisona. La paciente ingresó por fiebre, dolor e impotencia funcional en pierna derecha. Comprobamos la existencia de una placa de 8 por 4 cm eritematoedematosa. La tratamos con antibióticos sin mejoría, por lo que realizamos un estudio histopatológico de piel que mostró cambios citopáticos compatibles con infección por CMV. Los cultivos bacteriológicos y micológicos fueron negativos. La inmunohistoquímica específica para CMV y el estudio de reacción en cadena de la polimerasa (PCR de la biopsia de piel fueron positivas, al igual que la antigenemia. El tratamiento con ganciclovir produjo la mejoría del cuadro clínico. En la literatura revisada no hemos encontrado la celulitis como manifestación de enfermedad cutánea por CMV.

  14. Renal liposarcoma

    Directory of Open Access Journals (Sweden)

    Diogo A.L. Bader

    2004-06-01

    Full Text Available INTRODUCTION: Liposarcoma is a malignant mesenchymal tumor frequently located in retroperitoneum, and rarely presenting an isolated lesion in kidney. CASE REPORT: Female, Caucasian, 49-year old patient, with family history of renal polycystic disease, was selected for organ donation. During preoperative examinations a renal pleomorphic liposarcoma was detected. She was treated with radical nephrectomy and remains asymptomatic, without evidences of recurrence in control ecographic examinations after a 4-year follow-up. COMMENTS: Renal liposarcoma is a rare tumor. We report one case incidentally diagnosed during a routine pre-transplantation assessment in renal donor.

  15. RENAL CRYOABLATION

    Directory of Open Access Journals (Sweden)

    A. V. Govorov

    2012-01-01

    Full Text Available Renal cryoablation is an alternative minimally-invasive method of treatment for localized renal cell carcinoma. The main advantages of this methodology include visualization of the tumor and the forming of "ice ball" in real time, fewer complications compared with other methods of treatment of renal cell carcinoma, as well as the possibility of conducting cryotherapy in patients with concomitant pathology. Compared with other ablative technologies cryoablation has a low rate of repeat sessions and good intermediate oncological results. The studies of long-term oncological and functional results of renal cryoablation are presently under way.

  16. Renal disease

    National Research Council Canada - National Science Library

    Espinosa-Cuevas, María de Los Ángeles

    2016-01-01

    Chronic renal failure in its various stages, requires certain nutritional restrictions associated with the accumulation of minerals and waste products that cannot be easily eliminated by the kidneys...

  17. Renal cancer.

    NARCIS (Netherlands)

    Corgna, E.; Betti, M.; Gatta, G.; Roila, F.; Mulder, P.H.M. de

    2007-01-01

    In Europe, renal cancer (that is neoplasia of the kidney, renal pelvis or ureter (ICD-9 189 and ICD-10 C64-C66)) ranks as the seventh most common malignancy in men amongst whom there are 29,600 new cases each year (3.5% of all cancers). Tobacco, obesity and a diet poor in vegetables are all

  18. Renal cancer

    NARCIS (Netherlands)

    Corgna, Enrichetta; Betti, Maura; Gatta, Gemma; Roila, Fausto; De Mulder, Pieter H. M.

    2007-01-01

    In Europe, renal cancer (that is neoplasia of the kidney, renal pelvis or ureter (ICD-9 189 and ICD-10 C64-C66)) ranks as the seventh most common malignancy in men amongst whom there are 29,600 new cases each year (3.5% of all cancers). Tobacco, obesity and a diet poor in vegetables are all

  19. Renal angiomyolipoma

    DEFF Research Database (Denmark)

    Holm-Nielsen, P; Sørensen, Flemming Brandt

    1988-01-01

    features. However, a smaller number of smooth muscle cells also contained lipid, thus simulating an intermediate cell stage between adipose- and smooth muscle cells. The abnormal thickening of the subendothelial spaces contained collagen fibrils in a homogeneous matrix, fibroblast-like cells and non......-specific vesicular structures. These findings suggest a secondary vascular damage, i.e. the thickened vessels may not be a primary, integral part of renal angiomyolipoma. Evidence of a common precursor cell of renal angiomyolipoma was not disclosed. It is concluded that renal angiomyolipoma is a hamartoma composed...

  20. Renal scan

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003790.htm Renal scan To use the sharing features on this ... anaphylaxis . Alternative Names Renogram; Kidney scan Images Kidney anatomy Kidney - blood and urine flow References Chernecky CC, ...

  1. Nutrición y enfermedad renal

    OpenAIRE

    Iris de Castaño; Consuelo de Rovetto

    2007-01-01

    El riñón juega un papel importante en la regulación interna del organismo a través de las funciones excretoras, metabólicas y endocrinas. La insuficiencia renal aguda, IRA, se caracteriza por un rápido deterioro de la función renal con acumulación de productos nitrogenados como la urea y la creatinina y desequilibrio del agua y de los electrólitos. La falla renal crea un estado de desequilibrio metabólico proporcional a la perdida de la función renal. Dentro de los factores importantes para d...

  2. Renal Hemangiopericytoma

    Directory of Open Access Journals (Sweden)

    İbrahim Halil Bozkurt

    2015-03-01

    Full Text Available Hemangiopericytoma is an uncommon perivascular tumor originating from pericytes in the pelvis, head and tneck, and the meninges; extremely rarely in the urinary system. We report a case of incidentally detected renal mass in which radiologic evaluation was suggestive of renal cell carcinoma. First, we performed partial nephrectomy, and then, radical nephrectomy because of positive surgical margins and the pathological examination of the surgical specimen that revealed a hemangiopericytoma. No additional treatment was administered.

  3. Influência do pneumoperitônio nas funções hepática e renal e na liberação de citocinas pró-inflamatórias em modelo experimental de endotoxemia induzida por lipopolissacarídeo de Escherichia coli Influence of pneumoperitoneum on the hepatic and renal functions and the release of pro-inflammatory cytokines in the endotoxemia model induced by lipopolyssacharide from Escherichia coli

    Directory of Open Access Journals (Sweden)

    Matheus Martin Macri

    2009-12-01

    Full Text Available RACIONAL: A videocirurgia pode apresentar complicações inerentes ao método e dentre elas destacam-se as relacionadas ao aumento da pressão na cavidade intra-abdominal. OBJETIVO: Analisar os efeitos do pneumoperitônio em modelo experimental de endotoxemia causada por lipopolissacarídeo. MÉTODO: Foram utilizados 32 ratos Wistar dos quais foi coletado sangue 24 horas prévias para obtenção dos valores de referência nas provas de função renal, hepática e do estado endotóxico (contagens total e diferencial de leucócitos, contagem de plaquetas e dosagens de lipopolissacarídeo, TNFα, IL6. A seguir os ratos foram separados em quatro grupos com oito: grupos controle inoculados com lipopolissacarídeo (10 mg/kg via intraperitoneal e mantidos por quatro e 11 horas (C-LPS4 e C-LPS11. Grupo C-PP, submetido ao pneumoperitônio por CO2 por uma hora e mantido sob observação por seis horas. Grupo experimento (E inoculados com 10 mg/kg de lipopolissacarídeo por via intraperitoneal, após quatro horas submetidos ao pneumoperitônio por CO2 por uma hora e mantidos sob observação por seis horas. Ao término destes períodos foram coletadas amostras de sangue para as mesmas avaliações iniciais. Utilizou-se o método de T-Student para as comparações dos resultados, com nível de significância de 0,05. RESULTADOS: Em comparação aos valores iniciais e aos grupos controle, o grupo E apresentou maiores valores nas dosagens de creatinina e uréia, bilirrubina direta, ALT e TAP, aumento nas dosagens de IL6, TNFα e diminuição de plaquetas, aumento de leucócitos e bastonetes e detecção de endotoxina circulante. CONCLUSÃO: O pneumoperitônio por dióxido de carbono induz aumentos na liberação de TNFα, IL6, piora das funções hepática e renal em modelo experimental de endotoxemia induzida por lipopolissacarídeo.BACKGROUND: Videosurgery can bring complications with it´s manipulation and among them the hyperpression into the abdominal

  4. Immunohistochemical changes in kidney glomerular and tubular proteins caused by rattlesnake (Crotalus vegrandis venom Cambios inmunohistoquímicos en proteínas de túbulo y glomérulo renal causadas por el veneno de la serpiente de cascabel (Crotalus vegrandis

    Directory of Open Access Journals (Sweden)

    María E. Girón

    2003-10-01

    Full Text Available Renal damage is an important cause of death in patients who have survived the early effects of severe crotalid envenomation. Extracellular matrix of renal tissue is altered by Crotalus toxin activities. The aim of this study was to describe how cytoskeletal proteins and basal membrane components undergo substantial alterations under the action of Crotalus vegrandis crude venom and its hemorrhagic fraction (Uracoina-1 in mice. To detect the proteins in question, the immunoperoxidase method with monoclonal and polyclonal antibodies was used. Cell types within renal lesions were characterized by phenotypic identification, by means of immunohistologic analysis of marker proteins using different primary antibodies against mesangial cells, endothelial cells, cytoskeletal proteins (intermediate filament, extracellular matrix and basal membranes. Samples for morphological study by standard procedures (biotin-streptavidin-peroxidase technique using light microscopy were processed. Positive and negative controls for each antigen tested in the staining assay were included. After crude venom and hemorrhagic fraction inoculation of mice, the disappearance of cytoskeletal vimentin and desmin and collagen proteins in the kidney was observed. In extracellular matrix and basal membranes, collagen type IV from envenomed animals tends to disappear from 24 h to 120 h after venom injection.El daño renal es una causa importante de muerte en pacientes que sobreviven a los efectos iniciales de los severos envenenamientos crotálicos. El objetivo de este estudio ha sido el describir como las proteínas del citoesqueleto y los componentes de membrana basal muestran alteraciones importantes en su manifestación, bajo la acción del veneno crudo de Crotalus vegrandis y una fracción hemorrágica (Uracoina-1 del mismo veneno ya que, la matriz extracelular del tejido renal es alterada por la actividad de estas toxinas. Para detectar las proteínas en cuestión se utiliz

  5. Incidencia de insuficiencia renal aguda en niños hospitalizados por quemaduras en el Hospital Universitario San Vicente de Paúl de Medellín, 2007-2008

    OpenAIRE

    José William Cornejo Ochoa; Juan José Vanegas Ruiz; Sandra Milena Brand; Carolina Giraldo Alzate

    2008-01-01

    INTRODUCCIÓN: las quemaduras en niños se han identificado como causa principal de trauma y su asociación con insuficiencia renal aguda es una de las complicaciones más temidas debido a su alta tasa de mortalidad. OBJETIVO: establecer la incidencia de insuficiencia renal aguda y describir algunos de los factores asociados en niños quemados menores de 18 años atendidos en el Hospital Universitario San Vicente de Paúl de Medellín. MATERIALES Y MÉTODOS: estudio de cohorte prospectivo y descriptiv...

  6. Renal leiomyosarkom

    OpenAIRE

    A, Gelincik İ Tok

    2013-01-01

    Renal leiomyosarkomlar, oldukça nadirdir ve primer böbrek malignitelerinin %1-3'ünü oluştururlar. Renal sarkomların prognozu kötüdür ve özellikle sarkomatoid renal hücreli karsinomdan ayrımının yapılması gerekir. Hastanın klinik prezentasyonu ve radyolojik bulguları kesin olarak preoperatif tanı koymaya yardımcı değildir. Başlıca tedavi adjuvan radyoterapi veya kemoterapi ile birlikte veya tek başına radikal nefrektomidir. Prognozu kötüdür. Tanısını immünohistokimya ile doğruladığımız pr...

  7. Trauma renal

    OpenAIRE

    Pereira Júnior, Gerson Alves; Paganelli, Fernando; Scarpelini, Sandro; Stracieri, Luís Donizetti Silva; Féres, Ornar; Andrade, José Ivan de

    1999-01-01

    Apresentamos uma revisão sobre trauma renal, com ênfase na avaliação radiológica, particularmente com o uso da tomografia computadorizada, que tem se tornado o exame de eleição, ao invés da urografia excretora e arteriografia. O sucesso no tratamento conservador dos pacientes com trauma renal depende de um acurado estadiamento da extensão da lesão, classificado de acordo com a Organ Injury Scaling do Colégio Americano de Cirurgiões. O tratamento conservador não-operatório é seguro e consiste ...

  8. Sarcoidose renal

    OpenAIRE

    AQUINO, MARIA ENEDINA CLAUDINO DE; SALES, ROBERTA KARLA BARBOSA DE; SANTOS, JOSÉ ANTÔNIO FREIRE DOS; RÉGIS, ANA LIDIA; MORRONE, NELSON

    2001-01-01

    Em uma mulher de 62 anos, branca, em avaliação pré-operatória de facectomia, foram detectadas alterações urinárias, tendo sido firmados os diagnósticos de calculose renal esquerda e exclusão renal homolateral. No pré-operatório da nefrectomia foram evidenciados processo pulmonar intersticial bilateral e adenopatia torácica, cuja investigação foi adiada para após a cirurgia. No rim retirado foram detectados granulomas epitelióides não necrotizantes, o mesmo ocorrendo posteriormente em biópsia ...

  9. Renal transplantation

    OpenAIRE

    Bugeja, Mark

    1983-01-01

    The first Renal Transplantation ever to be carried out in Malta was performed on the 22nd April, 1983, a day that may well be included in the Medical History of our Islands. This .event is another step -forward following the introduction, not very long'ago, at St. Luke's Hospital, of Haemodialysis or as the lay- man would call it, the 'Kidney Machine'. What follows is not meant to be a case- presentation proper but is intended to serve as a base over which some pros and cons of renal transpla...

  10. Renal and urinary findings in 20 patients with Williams-Beuren syndrome diagnosed by fluorescence in situ hybridization (FISH Achados renais e urinários em 20 pacientes com síndrome de Williams-Beuren diagnosticados pelo teste de hibridização in situ por fluoresceína (FISH

    Directory of Open Access Journals (Sweden)

    Sofia Mizuho Miura Sugayama

    2004-01-01

    Full Text Available PURPOSE: Williams-Beuren syndrome is a rare multiple anomalies/mental retardation syndrome caused by deletion of contiguous genes at chromosome region 7q11.23. The aim of this work was to determine the frequency and the types of renal and urinary tract anomalies in 20 patients with Williams-Beuren syndrome. METHODS: The fluorescence in situ hybridization test using a LSI Williams syndrome region DNA probe was performed for all 20 patients to confirm the diagnosis of Williams-Beuren syndrome. A prospective study was performed in order to investigate renal and urinary aspects using laboratory assays to check renal function, ultrasonography of the kidneys and urinary tract, voiding cystourethrogram and urodynamics. RESULTS: Deletion of the elastin gene (positive fluorescence in situ hybridization test was found in 17 out of 20 patients. Renal alterations were diagnosed in 5 of 17 (29% the patients with the deletion and in 1 of 3 patients without the deletion. Fourteen patients with the deletion presented dysfunctional voiding. Arterial hypertension was diagnosed in 3 patients with deletions and 1 of these presented bilateral stenosis of the renal arteries. CONCLUSIONS: Due to the high incidence of renal and urinary abnormalities in Williams-Beuren syndrome, performing a systematic laboratory and sonographic evaluation of the patients is recommended.OBJETIVO: A síndrome de Williams-Beuren é uma rara síndrome de deleção de genes contíguos que cursa com múltiplas anomalias congênitas, deficiência mental e anomalias renais e urinárias. O objetivo deste trabalho foi determinar a freqüência e os tipos de anomalias renais e urinárias em 20 pacientes com síndrome de Williams-Beuren diagnosticados pelo teste de hibridização in situ por fluorescência. MÉTODOS: Estudou-se prospectivamente os aspectos renais e urinários através de avaliação laboratorial da função renal, ultrassonografia de rins e vias urinárias, uretrocistografia

  11. Hiperparatiroidismos renales

    OpenAIRE

    Malagón Castro, Valentín

    2011-01-01

    En la presente monografía presentamos una síntesis, lo más completa posible, del gran problema de los Hiperparatirodismos secundarios a lesiones renales, enfocando su estudio con un criterio unicista, con el objeto de hacer más didáctico este amplio capítulo de la patología.

  12. Renal denervation

    DEFF Research Database (Denmark)

    Olsen, Lene Kjær; Kamper, Anne-Lise; Svendsen, Jesper Hastrup

    2015-01-01

    PURPOSE OF REVIEW: Renal denervation (RDN) has, within recent years, been suggested as a novel treatment option for patients with resistant hypertension. This review summarizes the current knowledge on this procedure as well as limitations and questions that remain to be answered. RECENT FINDINGS...

  13. Trauma renal

    Directory of Open Access Journals (Sweden)

    Gerson Alves Pereira Júnior

    Full Text Available Apresentamos uma revisão sobre trauma renal, com ênfase na avaliação radiológica, particularmente com o uso da tomografia computadorizada, que tem se tornado o exame de eleição, ao invés da urografia excretora e arteriografia. O sucesso no tratamento conservador dos pacientes com trauma renal depende de um acurado estadiamento da extensão da lesão, classificado de acordo com a Organ Injury Scaling do Colégio Americano de Cirurgiões. O tratamento conservador não-operatório é seguro e consiste de observação contínua, repouso no leito, hidratação endovenosa adequada e antibioti- coterapia profilática, evitando-se uma exploração cirúrgica desnecessária e possível perda renal. As indicações para exploração cirúrgica imediata são abdome agudo, rápida queda do hematócrito ou lesões associadas determinadas na avaliação radiológica. Quando indicada, a exploração renal após controle vascular prévio é segura, permitindo cuidadosa inspeção do rim e sua reconstrução com sucesso, reduzindo a probabilidade de nefrectomia.

  14. Renale Osteopathie

    OpenAIRE

    Horn S

    2001-01-01

    Die renale Osteopathie umfaßt Erkrankungen des Knochens, die bei Patienten mit chronischen Nierenerkrankungen auftreten, wie den sekundären bzw. tertiären Hyperparathyreoidismus, die adynamische Knochenerkrankung und die Osteopathie nach Nierentransplantation. Durch die Identifikation des Kalzium-Sensing-Rezeptors bzw. des Vitamin D-Rezeptors hat sich unser Verständnis der Zusammenhänge in den letzten Jahren erheblich verbessert. Neue Medikamente versprechen effizientere Prophylaxe- und Thera...

  15. Renale Knochenerkrankungen

    Directory of Open Access Journals (Sweden)

    Mayer G

    2008-01-01

    Full Text Available Störungen des Mineral- und Knochenstoffwechsels sind bei fast allen Patienten mit chronischen Nierenerkrankungen anzutreffen. Pathogenetisch spielt eine Neigung zur Phosphatretention bei einer Reduktion der glomerulären Filtrationsrate die zentrale Rolle. Neben typischen, aber sehr variablen Veränderungen der Knochenstruktur (renale Osteopathie besteht auch eine sehr enge Assoziation zwischen diesen Störungen und dem massiv erhöhten kardiovaskulären Risiko der Patienten.

  16. Renal tuberculosis

    OpenAIRE

    Džamić Zoran; Dimitrijević Vladan

    2016-01-01

    Tuberculosis is still a significant health problem in the world, mostly in developing countries. The special significance lies in immunocompromised patients, particularly those suffering from the HIV. Urogenital tuberculosis is one of the most common forms of extrapulmonary tuberculosis, while the most commonly involved organ is the kidney. Renal tuberculosis occurs by hematogenous dissemination of mycobacterium tuberculosis from a primary tuberculosis foci in the body. Tuberculosis is charac...

  17. Hiperparatiroidismos renales

    Directory of Open Access Journals (Sweden)

    Valentín Malagón Castro

    1957-04-01

    Full Text Available En la presente monografía presentamos una síntesis, lo más completa posible, del gran problema de los Hiperparatirodismos secundarios a lesiones renales, enfocando su estudio con un criterio unicista, con el objeto de hacer más didáctico este amplio capítulo de la patología.

  18. Obesity and renal hemodynamics

    NARCIS (Netherlands)

    Bosma, R. J.; Krikken, J. A.; van der Heide, J. J. Homan; de Jong, P. E.; Navis, G. J.

    2006-01-01

    Obesity is a risk factor for renal damage in native kidney disease and in renal transplant recipients. Obesity is associated with several renal risk factors such as hypertension and diabetes that may convey renal risk, but obesity is also associated with an unfavorable renal hemodynamic profile

  19. DISEÑO E IMPLEMENTACIÓN DE UN PROTOTIPO DE SISTEMA DE IDENTIFICACIÓN POR RADIOFRECUENCIA PARA LA VERIFICACIÓNN DE INFORMACIÓN DE VEHÍCULOS

    Directory of Open Access Journals (Sweden)

    Alberto Acosta López

    2015-12-01

    Full Text Available En todas las grandes urbes a nivel mundial el control del flujo vehicular se ha convertido en un problema, dado que la misma labor de control contribuye a la congestión reinante. Esto nos llevó a buscar un sistema control vehicular que fuera ágil, etéreo y efectivo. La propuesta se basa en el diseño e implementación de un prototipo de aplicación, construido sobre el sistema operativo Android utilizando tecnología NFC. Para el logro de este prototipo fue necesario implementar una arquitectura de software tipo cliente servidor, teniendo en cuenta que el sistema contó con elementos de servicios web, una página web y un aplicativo móvil, los cuales internamente se basan en diversos aspectos tecnológicos; de igual forma, la tecnología NFC hace que se pueda obtener información de manera simple. A partir de estos factores fue posible obtener una versión funcional de este aplicativo.Design and implementation of a prototype RFID system to verify vehicle informationABSTRACTIn all the greatest cities worldwide, the control of the traffic flow has become in a huge problem because the control task contributes to the prevailing congestion. This took us to look for a vehicular control system that would be agile, ethereal and effective. The proposal is based in the design and implementation of an application builded in the operative system Android using the NFC technology. For the success of this project was necessary to implement an client – server architecture, considering that the system uses web services, web pages and a mobile application, each one is based on technological aspects and NFC technology, that makes possible getting information in a simple way. From this factors was possible to obtain a functional version of the application.Keywords: android, GPS, identification, NFC, RFID, TAG, vehicle, web service.

  20. Valorization of the GAFCHROMIC XR-R film for radiation dose estimation in the skin; Valoracion de las peliculas Gafchromic XR-R para estimacion de dosis a piel en ''ablacion por radiofrecuencia''

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Garcia, M.; Otero Martinez, C.; Camino, X. M.; Sendon del Rio, J. R.; Luna Vega, V.; Lobato Busto, R.; Mosquera Sueiro, J.; Pombar Camean, M.

    2006-07-01

    The adequacy of the couple formed by the GAFCHROMIC XR-R film and the MICROTEK Scan Maker 8700 for skin dose determination has been evaluated. The main advantages are the ease of use the films, since it can be manipulated without special care and the ability to archive it in the dosimetric history of the patient. The main limiting factors coming from the scanner are the reproducibility over time and noise in the digitization; it is shown that this last component can be minimized at the cost of resolution. From the film itself, the limiting factors are the inter and intra film uniformity. Contributing an 6,5% to the overall uncertainty in dose determination. Overall, it has been shown that skin dose determination is possible with this film with an uncertainty below 10%. (Author)

  1. Sistemas de identificación por radiofrecuencia, código de barras y su relación con la gestión de la cadena de suministro

    National Research Council Canada - National Science Library

    Alexander Correa Espinal

    2010-01-01

    .... Para ello, se compilan conceptos generales de los sistemas de identificación presentando sus definiciones, componentes de hardware/software, aplicaciones en la cadena de suministro y el uso que grandes, medianas...

  2. Bilateral Renal Mass-Renal Disorder: Tuberculosis

    Directory of Open Access Journals (Sweden)

    Ozlem Tiryaki

    2013-01-01

    Full Text Available A 30-year-old woman has presented complaining of weakness and fatigue to her primary care physician. The renal sonography is a routine step in the evaluation of new onset renal failure. When the renal masses have been discovered by sonography in this setting, the functional imaging may be critical. We reported a case about bilateral renal masses in a young female patient with tuberculosis and renal insufficiency. Magnetic resonance (MR has revealed the bilateral renal masses in patient, and this patient has been referred to our hospital for further management. The patient’s past medical and surgical history was unremarkable.

  3. Proximal renal tubular acidosis

    Science.gov (United States)

    Renal tubular acidosis - proximal; Type II RTA; RTA - proximal; Renal tubular acidosis type II ... by alkaline substances, mainly bicarbonate. Proximal renal tubular acidosis (Type II RTA) occurs when bicarbonate is not ...

  4. Bilateral renal artery variation

    OpenAIRE

    Üçerler, Hülya; Üzüm, Yusuf; İkiz, Z. Aslı Aktan

    2015-01-01

    Each kidney is supplied by a single renal artery, although renal artery variations are common. Variations of the renal arteryhave become important with the increasing number of renal transplantations. Numerous studies describe variations in renalartery anatomy. Especially the left renal artery is among the most critical arterial variations, because it is the referred side forresecting the donor kidney. During routine dissection in a formalin fixed male cadaver, we have found a bilateral renal...

  5. Drug-induced renal injury

    African Journals Online (AJOL)

    induced renal toxicity into four major renal syndromes: • acute renal failure. • chronic renal failure. • glomerulonephritis. • tubulopathies. These major renal syndromes are discussed in further detail below (see summary in Table I). Acute renal failure. Drugs can cause acute renal failure by causing pre-renal, intrinsic or.

  6. Renal tuberculosis

    Directory of Open Access Journals (Sweden)

    Džamić Zoran

    2016-01-01

    Full Text Available Tuberculosis is still a significant health problem in the world, mostly in developing countries. The special significance lies in immunocompromised patients, particularly those suffering from the HIV. Urogenital tuberculosis is one of the most common forms of extrapulmonary tuberculosis, while the most commonly involved organ is the kidney. Renal tuberculosis occurs by hematogenous dissemination of mycobacterium tuberculosis from a primary tuberculosis foci in the body. Tuberculosis is characterized by the formation of pathognomonic lesions in the tissues - granulomata. These granulomata may heal spontaneously or remain stable for years. In certain circumstances in the body associated with immunosuppression, the disease may be activated. Central caseous necrosis occurs within tuberculoma, leading to formation of cavities that destroy renal parenchyma. The process may gain access to the collecting system, forming the caverns. In this way, infection can be spread distally to renal pelvis, ureter and bladder. Scaring of tissue by tuberculosis process may lead to development of strictures of the urinary tract. The clinical manifestations are presented by nonspecific symptoms and signs, so tuberculosis can often be overlooked. Sterile pyuria is characteristic for urinary tuberculosis. Dysuric complaints, flank pain or hematuria may be presented in patients. Constitutional symptoms of fever, weight loss and night sweats are presented in some severe cases. Diagnosis is made by isolation of mycobacterium tuberculosis in urine samples, by cultures carried out on standard solid media optimized for mycobacterial growth. Different imaging studies are used in diagnostics - IVU, CT and NMR are the most important. Medical therapy is the main modality of tuberculosis treatment. The first line anti-tuberculosis drugs include isoniazid, rifampicin, pyrazinamide and ethambutol. Surgical treatment is required in some cases, to remove severely damaged kidney, if

  7. Correlación entre índice de catabolismo proteico medido por el modelo cinético de la urea y la encuesta dietética en niños con insuficiencia renal crónica en diálisis.

    Directory of Open Access Journals (Sweden)

    Susan CORNEJO FLORES

    2006-04-01

    Full Text Available Objetivo: Determinar la correlación entre ICP calculado por el modelo cinético de urea y la ingesta proteica determinada mediante encuesta dietética. Material y métodos: En el estudio analítico de correlación, se incluyeron 15 niños con insuficiencia renal crónica (IRC evaluados en un periodo de un año de seguimiento. Se determinó el ICP mediante la encuesta de Frecuencia de Consumo y recordatorio de 24 h por 3 días y el modelo cinético de la úrea, al inicio y al final del estudio. Se determinó albúmina sérica, urea sérica pre y post recolección de orina en el periodo ínterdialítico y urea en orina del periodo interdialítico. Resultados. El 46,67%(7 fueron del sexo femenino y 53,33%(8 masculino. La edad fue 15 ±2 años. Al inicio, 20% de los pacientes tuvieron niveles de albúmina sérica normales y al final del estudio fue 86,67%. El promedio del ICP calculado al inicio fue 0,993±0,27 y 0,996 ± 0,28 por modelo cinético y encuesta dietética respectivamente y su correlación fue r = 0,9962 y R²= 0,9924. Al final del estudio fue 1,07± 0,28 calculado por la encuesta y de 1,06± 0,27 por el modelo cinético de generación de urea y su correlación fue de r =0,9973 y R²= 0,9924. Conclusión: Existe buena correlación entre el ICP calculado por el modelo cinético de generación de urea y la ingesta proteica determinada por la encuesta dietética (Rev Med Hered 2006;17:77-80.

  8. Renale Osteopathie

    Directory of Open Access Journals (Sweden)

    Horn S

    2001-01-01

    Full Text Available Die renale Osteopathie umfaßt Erkrankungen des Knochens, die bei Patienten mit chronischen Nierenerkrankungen auftreten, wie den sekundären bzw. tertiären Hyperparathyreoidismus, die adynamische Knochenerkrankung und die Osteopathie nach Nierentransplantation. Durch die Identifikation des Kalzium-Sensing-Rezeptors bzw. des Vitamin D-Rezeptors hat sich unser Verständnis der Zusammenhänge in den letzten Jahren erheblich verbessert. Neue Medikamente versprechen effizientere Prophylaxe- und Therapiemöglichkeiten. Wir beeinflussen dadurch nicht nur die Morbidität und Lebensqualität, sondern auch die Mortalität unserer Patienten.

  9. Cisto multilocular renal

    Directory of Open Access Journals (Sweden)

    Ennio Gabriel

    Full Text Available O cisto multilocular renal é uma tumoração rara, de etiopatogenia discutida, que apresenta um aspecto macroscópico característico (parecendo favos de mel mas histologia variável, o que ocasionou uma vasta sinonímia para esta afecção. Com os modernos métodos de diagnóstico por imagem, estes tumores podem ser suspeitados no pré-operatório, mas antes eram rotulados como provável nefroblastoma (Tumor de Wilms. Os autores descrevem as características de cinco casos observados nos Serviços de Cirurgia Pediátrica dos Hospitais Getúlio Vargas e da Lagoa, do Rio de Janeiro, e no Hospital Universitário de João Pessoa (Paraíba. Em todos, o sintoma predominante era uma massa abdominal, mas em um havia também hipertensão arterial. Todos os pacientes foram submetidos a nefrectomia e tiveram boa evolução pós-operatória. Apesar de pouco freqüente, o cisto multilocular renal deve ser lembrado no diagnóstico de qualquer massa renal em crianças, especialmente naquelas com menos de dois anos de idade, devido ao prognóstico favorável em comparação com o do tumor de Wilms. No adulto, o diagnóstico diferencial é feito principalmente com o adenocarcinoma cístico.

  10. Renal calculus

    CERN Document Server

    Pyrah, Leslie N

    1979-01-01

    Stone in the urinary tract has fascinated the medical profession from the earliest times and has played an important part in the development of surgery. The earliest major planned operations were for the removal of vesical calculus; renal and ureteric calculi provided the first stimulus for the radiological investigation of the viscera, and the biochemical investigation of the causes of calculus formation has been the training ground for surgeons interested in metabolic disorders. It is therefore no surprise that stone has been the subject of a number of monographs by eminent urologists, but the rapid development of knowledge has made it possible for each one of these authors to produce something new. There is still a technical challenge to the surgeon in the removal of renal calculi, and on this topic we are always glad to have the advice of a master craftsman; but inevitably much of the interest centres on the elucidation of the causes of stone formation and its prevention. Professor Pyrah has had a long an...

  11. Recurrent Acremonium infection in a kidney transplant patient treated with voriconazole: a case report Infecção recidivante por Acremonium em paciente transplantado renal tratado com voriconazol: relato de caso

    Directory of Open Access Journals (Sweden)

    Felipe Francisco Tuon

    2010-08-01

    Full Text Available Acremonium infection is rare and associated with immunosuppression. A case of recurrent cutaneous Acremonium infection after short term voriconazole use is described. Surgical resection was the definitive therapy. Oral voriconazole was used in the treatment of Acremonium infection, but recurrence was associated with short therapy. Prolonged antifungal therapy and surgical resection are discussed for the treatment of localized lesions.Infecção por Acremonium é rara e pode estar associada com imunossupressão. Descrevemos um caso de infecção recorrente de pele por Acremonium após tratamento breve com voriconazol. Ressecção cirúrgica foi o tratamento definitivo. Terapia prolongada com antifúngicos e ressecção cirúrgica são discutidas para o tratamento de doenças fúngicas localizadas.

  12. Traumatismo Renal

    OpenAIRE

    Carlos Martinez S.

    2017-01-01

    Introdução: A realização deste trabalho visa a elaboração de uma revisão sistematizada subordinada à temática da traumatologia renal. Objectivos: Os principais objectivos deste trabalho são: apurar a etiologia, definir a classificação, analisar o diagnóstico e expôr o tratamento e as complicações. Desenvolvimento: Os traumatismos são a principal causa de morte antes dos 40 anos. O rim é o órgão do aparelho génito-urinário mais frequentemente atingido. Os traumatismos renais são mais fre...

  13. [Hypertension and renal disease

    DEFF Research Database (Denmark)

    Kamper, A.L.; Pedersen, E.B.; Strandgaard, S.

    2009-01-01

    Renal mechanisms, in particular the renin-angiotensin system and renal salt handling, are of major importance in blood pressure regulation. Co-existence of hypertension and decreased renal function may be due to nephrosclerosis secondary to hypertension, or primary renal disease with secondary...

  14. Osteomalacia inducida por tumor: hemangiopericitoma rinosinusal

    Directory of Open Access Journals (Sweden)

    Enriqueta M. Serafini

    2013-02-01

    Full Text Available La osteomalacia inducida por tumor es una rara enfermedad del metabolismo óseo caracterizada por el aumento en la excreción de fosfato a nivel renal seguido de hipofosfatemia. Es causada por agentes fosfatúricos producidos por determinados tumores. La resección total del tumor resulta en la completa reversión de las anormalidades bioquímicas, la desaparición de las manifestaciones clínicas y los hallazgos en los estudios por imágenes. Presentamos el caso de un varón de 61 años con cuadro clínico y laboratorio compatibles con osteomalacia oncogénica inducida por tumor mesenquimático de localización rinosinusal. En nuestro caso el diagnóstico histológico correspondió a una neoplasia de tipo vascular: hemangiopericitoma.

  15. Nephrolithiasis Anotaciones sobre litiasis renal

    Directory of Open Access Journals (Sweden)

    Gonzálo Mejía

    1989-03-01

    Full Text Available

    Nephrolithiasis is a relatively common disease in medical practice. There are no recent, updated reviews on this topic in Colombian literature and to fill this need the present one was written. The different aspects of calcium lithiasis are analyzed in a practical and simplified although comprehensive way, emphasizing pathophysiology, patient evaluation, management of lithiasis (fluids, diet and drug therapy and new methods for stone removal. Other types of calculi are briefly discussed. Management of the renal colic is not included.

    La litiasis renal es un trastorno relativamente frecuente en la práctica médica. No existe en la literatura colombiana una revisión reciente y actualizada acerca de este tema por lo cual se escribió la presente. En una forma práctica y simplificada, pero completa, se analizan los diferentes aspectos relacionados con la litiasis por calcio y, brevemente, se mencionan otros tipos de cálculos. Se hace énfasis en fisiopatología, evaluación del paciente, manejo de la litiasis (líquidos, dieta y drogas y nuevos métodos de extracción del cálculo. No se incluye el manejo del cólico renal.

  16. TRATAMIENTO DE LA INSUFICIENCIA RENAL CRONICA, CON LASER-PUNTURA

    OpenAIRE

    JIMENEZ SERRANO, ANTONIO

    2010-01-01

    LA INSUFICIENCIA RENAL CRONICA (IRC), ES UNA ENFERMEDAD QUE EN LOS ULTIMOS TIEMPOS SE HA PRESENTADO CON MAYOR FRECUENCIA, ORIGINANDO GASTOS MUY ALTOS PARA LA ECONOMIA DE LAS FAMILIAS, Y PARA LAS INSTITUCIONES DE SALUD. EN ESTADOS UNIDOS EN 1995 SE PRESENTARON 59.000 CASOS NUEVOS DE IRC, PARA UNA INCIDENCIA DE 214 CASOS POR MILLON DE HABITANTES. CON TERAPIA DE REEMPLAZO RENAL (EN DIALISIS O CON TRASPLANTE RENAL) Y CON UNA PREVALENCIA DE 824 PACIENTES EN DIALISIS POR MILLON DE HABITANTES. ESTE...

  17. BILATERAL DUPLICATION OF RENAL ARTERIES

    OpenAIRE

    Prajkta A Thete; Mehera Bhoir; M.V.Ambiye

    2014-01-01

    Routine dissection of a male cadaver revealed the presence of bilateral double renal arteries. On the right side the accessory renal artery originated from the abdominal aorta just above the main renal artery. On the left side the accessory renal artery originated from the abdominal aorta about 1 cm above the main renal artery. Knowledge of the variations of renal vascular anatomy has importance in exploration and treatment of renal trauma, renal transplantation, renal artery embolization, su...

  18. Insuficiência renal aguda como manifestação inicial de linfoma de Burkitt renal

    OpenAIRE

    José Gastão Rocha Carvalho; Jean Rodrigo Tafarel; Wilson Beleski de Carvalho; Ana Paula de Azambuja; Elicéia Soraia Zenaro; Rodrigo Bendlin

    2006-01-01

    Relatamos o caso de um jovem de 14 anos que procurou atendimento médico por edema e hipertensão, sendo insuficiência renal aguda secundária a linfoma de Burkitt renal diagnosticada após avaliação laboratorial, de imagem e biópsia de massa tumoral renal.This case report is from a 14-year-old boy who had edema and hypertension due to a primary renal Burkitt's lymphoma, diagnosed through laboratory and image evaluation and kidney tumor biopsy.

  19. Relationship between sonographic renal length and renal ...

    African Journals Online (AJOL)

    Keywords: Sonography, Renal length, Renal. Parenchymal Thickness, Renal Biopsy. Résumé. But: Pour determiner 1e rapport entre l'épaisseur parenchymal rénale sonographic (RPT) et la longueur rénale (RL) dans le nigérien normal (1' adulte. Conception D'Etude: Le RL et le RPT de 309 sujets normaux dans la marge ...

  20. Distal renal tubular acidosis

    Science.gov (United States)

    ... this disorder. Alternative Names Renal tubular acidosis - distal; Renal tubular acidosis type I; Type I RTA; RTA - distal; Classical RTA Images Kidney anatomy Kidney - blood and urine flow References Krapf R, ...

  1. Kidney (Renal) Failure

    Science.gov (United States)

    ... How is kidney failure treated? What is kidney (renal) failure? The kidneys are designed to maintain proper fluid ... marrow and strengthen the bones. The term kidney (renal) failure describes a situation in which the kidneys have ...

  2. Cardio Renal Syndrome

    Directory of Open Access Journals (Sweden)

    KV Sahasranam

    2014-10-01

    Full Text Available For a long time, physicians have recognized that the kidney and the heart are related especially when there is severe dysfunction of either of them. Dysfunction of one of these organs seldom occurs in isolation. Of late the cardio renal syndrome is assuming significance because of its increasing incidence, awareness and complications. There is no definite definition of the cardio renal syndrome. However, an attempted definition states that it is a "decline in renal function in the setting of advanced heart failure". This definition does not cover the whole gamut of the cardio renal syndrome. Cardiac diseases are associated independently with a decrease in renal function and progression of existing renal disease. Chronic Kidney disease (CKD is an independent risk factor for cardiovascular events and outcome. This bidirectional nature of cardiac and renal interaction is called Cardio Renal Syndrome (CRS.

  3. Aneurisma da Artéria Renal: caso clínico Renal Artery Aneurysm

    Directory of Open Access Journals (Sweden)

    Joana Moreira

    2011-12-01

    Full Text Available Apresenta-se o caso clínico de um doente com volumoso aneurisma da artéria renal esquerda. Do sexo masculino, de 22 anos de idade, com lombalgia à esquerda com algumas semanas de evolução. Recorreu ao médico assistente que solicitou estudo imagiológico por ecografia abdominal. Detectada imagem sugestiva de aneurisma da aorta abdominal. Este achado motivou a transferência para o nosso Hospital onde foi admitido consciente e orientado, hemodinamicamente estável, apresentando uma massa pulsátil epigástrica, com frémito e sopro sistólico à auscultação. Angio-TC revelou um aneurisma da artéria renal esquerda com 16 cm de diâmetro. Dada a estabilidade clínica e topografia lesional optou-se por tentar embolizar, sem sucesso, o tronco da artéria renal esquerda antes da abordagem cirúrgica. O doente foi então submetido a Nefrectomia total esquerda por via toraco-abdominal. Pós-operatório sem complicações, locais ou sistémicas. Alta ao 8ºdia, mantendo boa função renal e com níveis normais de hemoglobina. Diagnóstico de aneurisma da artéria renal confirmado por estudo anátomo-patológico da peça operatória.One case of a large left renal artery aneurysm in a young patient 22 years old is presented. He appealed to his assistant physician a few weeks after development of left back pain. Abdominal ultrasound imaging study has been requested. Suggestive abdominal aortic aneurysm was detected. This finding led to the transfer to our hospital where he was admitted conscious and hemodynamically stable. A pulsatile epigastric mass with a systolic murmur on auscultation and thrill were detected. Angio-CT scan revealed a left renal artery aneurysm, 16 cm in diameter. Given the clinical stability and lesional topography we decide a previous embolization of left renal artery, unsuccessfully. The patient underwent then left total nephrectomy, through thoraco-abdominal incision. No local or systemic complications in the postoperative

  4. Relationship between sonographic renal length and renal ...

    African Journals Online (AJOL)

    Aim: To determine the relationship between sonographic renal parenchymal thickness (RPT) and renal length (RL) in normal adult Nigerian. Study design: The RL and RPT of 309 normal subjects within the age range of 18 – 80years were measured sonographically and prospectively. Correlation was performed between ...

  5. Renal inflammatory myofibroblastic tumor

    DEFF Research Database (Denmark)

    Heerwagen, S T; Jensen, C; Bagi, P

    2007-01-01

    Renal inflammatory myofibroblastic tumor (IMT) is a rare soft-tissue tumor of controversial etiology with a potential for local recurrence after incomplete surgical resection. The radiological findings in renal IMT are not well described. We report two cases in adults with a renal mass treated...

  6. Cardio-renal syndrome

    OpenAIRE

    Joseph Gnanaraj; Jai Radhakrishnan

    2016-01-01

    Cardio-renal syndrome is a commonly encountered problem in clinical practice. Its pathogenesis is not fully understood. The purpose of this article is to highlight the interaction between the cardiovascular system and the renal system and how their interaction results in the complex syndrome of cardio-renal dysfunction. Additionally, we outline the available therapeutic strategies to manage this complex syndrome.

  7. Citocinas e quimiocinas no transplante renal Cytokines and chemokines in renal transplantation

    Directory of Open Access Journals (Sweden)

    André Barreto Pereira

    2009-12-01

    Full Text Available O transplante renal é a melhor modalidade de terapia renal substutiva até o momento. Infelizmente, a sobrevida do enxerto é interrompida pelos episódios de rejeição aguda ou mesmo de fibrose intersticial/atrofia tubular. A dosagem de quimiocinas e citocinas urinárias como ferramenta alternativa para o diagnóstico dessas complicações tem sido relatada nos últimos anos. Estas substâncias estão sabidamente relacionadas com os mecanismos imunoinflamatórios do transplante renal, podendo ser detectadas no tecido renal, no plasma e na urina de pacientes transplantados. Drogas anti-inflamatórias, inibidores do sistema renina angiotensina e alguns antagonistas de receptores de citocinas, ainda utilizados em nível experimental, podem interferir com a expressão desses mediadores do sistema imune e, por conseguinte, alterar a evolução do transplante renal. Neste sentido, pretende-se neste artigo fazer uma revisão dos estudos sobre a mensuração de citocinas/quimiocinas e dos seus receptores na urina, no plasma e no tecido renal de pacientes transplantados, no intuito de avaliar uma possível associação entre os níveis desses mediadores e as complicações do transplante renal e sobrevida do enxerto.Renal transplantation is currently the best modality of renal substitutive therapy. Unfortunately graft survival is interrupted by episodes of acute rejection or even interstitial fibrosis/tubular atrophy. The measurement of urinary chemokines and cytokines as an alternative tool to diagnose these complications has been reported in past years. Those substances are clearly related to the immunoinflammatory mechanisms of renal transplantation, and can be detected in renal tissue, plasma, and urine samples of transplant recipients. Anti-inflammatory drugs, renin-angiotensin system inhibitors, and some antagonists of cytokines' receptors, although used only experimentally, can interfere with the expression of these immune system mediators and

  8. Compromiso renal en pacientes HIV+

    Directory of Open Access Journals (Sweden)

    María Marta Pernasetti

    2010-06-01

    Full Text Available Varias complicaciones nefrológicas pueden ocurrir durante la infección por el virus de la inmunodeficiencia humana (HIV especialmente en estadios avanzados de la enfermedad o relacionadas con otras infecciones o drogas. Poco conocida es la prevalencia de alteraciones renales subclínicas de pacientes HIV+ surgidas como complicación o relacionadas a la infección y/o tratamiento. Realizamos un corte transversal de pacientes asintomáticos HIV+ referidos en forma consecutiva al consultorio de nefrología para la detección de alteraciones nefrológicas. Se estudiaron 52 pacientes adultos mediante exámenes de sangre y orina, ultrasonido y biopsia renal. Edad media 39.9 ± 10.6 años, 88% varones, tiempo de diagnóstico de la infección: 53.2 ± 41.2 (2-127 meses. El 71% tenían síndrome de inmunodeficiencia adquirida (HIV-sida y el 77% recibían con antirretrovirales. La carga viral al momento del estudio fue 7043 ± 3322 copias y el recuento de CD4+ 484 ± 39 cel/mm³. El 30.7% presentó alteraciones del sedimento urinario: albuminuria: 16.6%, hematuria microscópica: 11.5%, hipercalciuria: 10.8% y cristaluria 6%. La media del filtrado glomerular fue 102.2 ± 22.9 ml/min (rango: 34-149. El 41% presentó anormalidades que corresponderían a enfermedad renal crónica (estadios 1 a 3. Los pacientes con alteraciones tenían mayor edad, con duración más prolongada de la infección. Las anomalías renales no se asociaron con mayor prevalencia de HIV-sida. Dos pacientes fueron biopsiados, con hallazgos de nefritis túbulo-intersticial crónica con cristales y glomerulonefritis por IgA. No hubo hallazgos de nefropatía por HIV. El amplio espectro y la alta prevalencia de anormalidades nefrológicas subclínicas encontradas sugieren que los pacientes asintomáticos HIV+ deberían realizar evaluaciones nefrológicas de rutina.

  9. Insuficiencia renal aguda

    Directory of Open Access Journals (Sweden)

    Juan Manuel Miyahira Arakaki

    2003-01-01

    Full Text Available Acute renal failure (ARF is a clinic syndrome characterized by decline in renal function occurring over a short time period. Is a relatively common complication in hospitalized critically ill patients and is associated with high morbidity and mortality. ARF has often a multi-factorial etiology syndrome usually approached diagnostically as pre-renal, post-renal, or intrinsic ARF. Most intrinsic ARF is caused by ischemia or nephrotoxins and is classically associated with acute tubular necrosis (ATN. High mortality is associated with severity of ARF, age more than 60 years old and presence of pulmonar and cardiovascular complications. Most patients who survive an episode of ARF recover sufficient renal function; however, 50% have subclinical functional defects in renal function or scarring on renal biopsy. ARF is irreversible in approximately 5% of patients, usually as a consequence of complete cortical necrosis. ( Rev Med Hered 2003; 14: 36-43.

  10. Evaluation of renal masses including retrograde renal brushing.

    Science.gov (United States)

    Gill, W B; Bibbo, M; Thomsen, S; Lu, C T

    1976-02-01

    1. The evaluation of renal masses has become an increasingly important topic because of the increasing incidence of kidney cancer, the improved cure rate of renal carcinoma with the proper preoperative diagnosis, and the proliferation in renal mass diagnostic methodology. 2. A variety of benign entities can produce an abnormal renal mass with attendant difficulties in being distinguished from malignant neoplasms. Among these benign lesions are: simple renal cysts, polycystic kidneys, congenital variations in renal size and shape, segmental renal hypertrophy, renal infarcts, intrarenal hematomas, renal hamartomas, renal leiomyomas, renal adenomas, renal angiomas, renal fibrolipomatosis, hydronephrosis of a duplicated collecting system, renal abscesses, and xanthogranulomatous pyelonephritis. 3. Nephrotomography, nephrosonography (ultrasound), adrenalin renal arteriography, selective magnification renal arteriography, renal venography and cavography, lymphangiography, renal scintillation scanning, abnormal levels of enzymes in blood and urine, immunologic studies (circulating antibodies and tumor-associated antigens), percutaneous needle aspirations, and retrograde renal brushing have all increased the diagnostic accuracy of determining the etiology of renal masses. None of these diagnostic procedures is infallible. A judicious combination of procedures gives the most reliable diagnostic results. 4. A search continues for (a) chemical agent(s) or a chemical profile in the blood or urine which is (are) specific for renal carcinoma, but as yet this is an investigational area and not a practical clinical reality.

  11. Efetividade da rizotomia facetária por radiofrequência na lombalgia mecânica crônica Efectividad de la rizotomía facetaria en lumbago mecánico Effectiveness of radiofrequency facet rhizotomy in the treatment of mechanical back pain

    Directory of Open Access Journals (Sweden)

    Lourimar Octaviano de Tolêdo

    2011-01-01

    Full Text Available OBJETIVO: Avaliar a efetividade da rizotomia facetária lombar por radiofreqüência no tratamento da dor lombar mecânica. MÉTODOS: Estudo prospectivo de 23 pacientes tratados com rizotomia por radiofrequência devido à dor lombar mecânica. O registro da intensidade da dor foi medido através de pontuação pela escala visual analógica (EVA e o número de analgésicos administrado a cada paciente no pré-operatório e nos controles de 3, 6 e 12 meses de pós-operatórios. RESULTADOS: Foi observado um declínio significativo da intensidade da dor (p OBJETIVO: Evaluar la efectividad de la rizotomía por radiofrecuencia facetaria lumbar en el tratamiento del lumbago mecánico. MÉTODOS: Estudio prospectivo de 23 pacientes tratados con rizotomía por radiofrecuencia en lumbago mecánico. El registro de la intensidad del dolor se midió por la puntuación de la escala analógica visual (VAS y el número de analgésicos administrados a cada paciente antes de la operación, y 3, 6 y 12 meses después de la intervención. RESULTADOS: Se observó una disminución significativa en la intensidad del dolor (p OBJECTIVE: To evaluate the effectiveness of radiofrequency lumbar facet rhizotomy in the treatment of mechanical low back pain. METHODS: Prospective study of 23 patients treated with radiofrequency rhizotomy in mechanical low back pain. The pain intensity was measured by the visual analog scale (VAS and the number of analgesics administered for each patient preoperatively and 3, 6 and 12 months postoperatively. RESULTS: We observed a significant decline in pain intensity (p<0.0001 in patients. CONCLUSIONS: In the series of patients assessed the treatment was effective in relieving symptoms of mechanical low back pain and the use of analgesics after the procedure was lower.

  12. Refractory anemia leading to renal hemosiderosis and renal failure.

    Science.gov (United States)

    Siddappa, Sujatha; Mythri, K M; Kowsalya, R; Parekh, Ashish

    2011-01-01

    Renal hemosiderosis is a rare cause of renal failure and, as a result, may not be diagnosed unless a detailed history, careful interpretation of blood parameters and renal biopsy with special staining is done. Here, we present a rare case of renal hemosiderosis presenting with renal failure.

  13. Refractory anemia leading to renal hemosiderosis and renal failure

    Directory of Open Access Journals (Sweden)

    Sujatha Siddappa

    2011-01-01

    Full Text Available Renal hemosiderosis is a rare cause of renal failure and, as a result, may not be diagnosed unless a detailed history, careful interpretation of blood parameters and renal biopsy with special staining is done. Here, we present a rare case of renal hemosiderosis presenting with renal failure.

  14. Salvageability of renal function following renal revascularisation in ...

    African Journals Online (AJOL)

    tion for the aortic arch and its branches.[1,2] It is ... Renal artery revascularisation procedures are usually carried out on children with renal artery stenosis from varied causes, including ... Salvageability of renal function in children who underwent renal revascularisation for Takayasu's arteritisinduced renal artery stenosis ...

  15. Linfoma renal: espectro de imagens na tomografia computadorizada Renal lymphoma: spectrum of computed tomography findings

    Directory of Open Access Journals (Sweden)

    Carol Pontes de Miranda Maranhão

    2005-04-01

    Full Text Available O acometimento renal no linfoma é raro, uma vez que o rim não possui tecido linfóide. O envolvimento secundário é mais freqüente, ocorrendo em até um terço das autópsias dos portadores de linfoma. Alguns autores acreditam que esta seja a única forma de acometimento renal, questionando a existência do linfoma primário. O linfoma renal representaria metástases hematogênicas ou invasão direta do tumor ocorrendo no espaço perirrenal. A partir destes tipos de envolvimento decorrem as formas de apresentação do linfoma renal: múltiplos nódulos, massa solitária, invasão renal por doença retroperitoneal contígua, doença perirrenal e infiltração difusa. Neste trabalho são discutidas e apresentadas imagens destas diferentes formas de acometimento.Isolated renal lymphoma is rare due to the absence of lymphoid tissue in kidneys. Secondary involvement occurs more frequently and is reported in up to 1/3 of the autopsies of patients who died from lymphoma. Some authors believe this is actually the only existing form of renal lymphoma. The involvement of the kidney by lymphoma would occur through hematogenic metastasis or direct tumor invasion of the perirenal space. These different types of involvement determine the several forms of renal lymphoma presentation: multiple nodules, solitary mass, renal invasion from contiguous retroperitoneal disease, perirenal disease and diffuse infiltration. In this study the imaging findings features of the different forms of involvement are presented and discussed.

  16. Recurrent renal giant leiomyosarcoma.

    Science.gov (United States)

    Öziş, Salih Erpulat; Gülpınar, Kamil; Şahlı, Zafer; Konak, Baha Burak; Keskin, Mete; Özdemir, Süleyman; Ataoğlu, Ömür

    2016-01-01

    Primary renal leiomyosarcomas are rare, aggressive tumors. They constitute 1-2% of adult malignant renal tumors. Although leiomyosarcomas are the most common histological type (50-60%) of renal sarcomas, information on renal leiomyosarcoma is limited. Local or systemic recurrences are common. The radiological appearance of renal leiomyosarcomas is not specific, therefore renal leiomyosarcoma cannot be distinguished from renal cell carcinoma by imaging methods in all patients. A 74-year-old female patient presented to our clinic complaining of a palpable mass on the right side of her abdomen in November 2012. The abdominal magnetic resonance imaging revealed a mass, 25 × 24 × 23 cm in size. Her past medical history revealed that she has undergone right radical nephrectomy in 2007, due to a 11 × 12 × 13 cm renal mass that was then reported as renal cell carcinoma on abdominal magnetic resonance imaging, but the pathological diagnosis was low-grade renal leiomyosarcoma. The most recent follow-up of the patient was in 2011, with no signs of local recurrence or distant metastases within this four-year period. The patient underwent laparotomy on November 2012, and a 35 cm retroperitoneal mass was excised. The pathological examination of the mass was reported as high-grade leiomyosarcoma. The formation of this giant retroperitoneal mass in 1 year can be explained by the transformation of the lesion's pathology from low-grade to a high-grade tumor.

  17. Iconografía por Resonancia Magnética

    Directory of Open Access Journals (Sweden)

    Jaime Gómez Gonzalez

    1987-04-01

    Full Text Available

    Iconografía, del griego “eikon” imagen y “graphein” dibujar, es la ciencia de las imágenes. La reproducción de imágenes del cuerpo humano puede hacerse por muchos medios, el más reciente, la Resonancia Magnética. Se trata de un procedimiento bien conocido por los químicos desde hace casi cuatro decenios y que se emplea para el análisis espectrográfico de cualquier substancia.

    Hace menos de diez años Raymond Damadian pudo utilizar este sistema para producir imágenes de cortes tomográficos del cuerpo humano en cualquier plano, sin utilizar radiaciones ionizantes. El perfeccionamiento del equipo ha llegado en los últimos tres años a producir imágenes con detalles anatómicos de gran perfección. Existe la posibilidad de hacer análisis espectrográfico en vivo, pero este procedimiento se encuentra aún en investigación.

    Para evaluar el sistema, el autor ha visitado varias fábricas en Europa y Estados Unidos, un número importante de laboratorios de centros hospitalarios en Nueva York, Houston, La Florida, y contribuyó a organizar en la Fundación Instituto Neurológico de Colombia, en colaboración con el Centro Internacional de Física, el I Seminario Internacional sobre Iconografía por Resonancia Magnética en abril de 1986, con participación de conferenciantes de Alemania, Bélgica, Dinamarca y los Estados Unidos.

    Se han compilado los informes de unos quince fabricantes, cuatro de ellos con representación en Colombia; se solicitaron cotizaciones, se realizaron estudios económicos y se consultó con arquitectos para adecuar el sitio donde se podría instalar el equipo en la Fundación Instituto Neuro lógico de Colombia, como un servicio más a la comunidad. En este momento se programa para 1987, el 11Seminario Internacional de Iconografía por Resonancia Magnética.

    El principio utilizado para obtener estas imágenes se basa en conceptos físicos muy complejos; sin embargo, se pueden

  18. Imaging of renal osteodystrophy

    Energy Technology Data Exchange (ETDEWEB)

    Jevtic, V. E-mail: vladimir.jevtic@mf.uni-lj.si

    2003-05-01

    Chronic renal insufficiency, hemodialysis, peritoneal dialysis, renal transplantation and administration of different medications provoke complex biochemical disturbances of the calcium-phosphate metabolism with wide spectrum of bone and soft tissue abnormalities termed renal osteodystrophy. Clinically most important manifestation of renal bone disease includes secondary hyperparathyroidism, osteomalacia/rickets, osteoporosis, adynamic bone disease and soft tissue calcification. As a complication of long-term hemodialysis and renal transplantation amyloid deposition, destructive spondyloarthropathy, osteonecrosis, and musculoskeletal infections may occur. Due to more sophisticated diagnostic methods and more efficient treatment classical radiographic features of secondary hyperparathyroidism and osteomalacia/rickets are now less frequently seen. Radiological investigations play an important role in early diagnosis and follow-up of the renal bone disease. Although numerous new imaging modalities have been introduced in clinical practice (scintigraphy, CT, MRI, quantitative imaging), plain film radiography, especially fine quality hand radiograph, still represents most widely used examination.

  19. EVOLUCIÓN DE LA TERAPIA SUSTITUTIVA RENAL

    OpenAIRE

    Coronada-Daza Jorge Antonio

    2015-01-01

    La enfermedad renal crónica (ERC) es un problema de salud pública mundial. La cuenta de alto costo de Colombia a 2013 reportó la existencia de 22.926 pacientes en terapia de diálisis, 5.941 con trasplante renal y 1.015.124 pacientes con ERC en estadios I - IV, potenciales a progresar y requerir terapia sustitutiva renal (TSR), para una incidencia aproximada de ingreso a diálisis de 65 personas por millón de habitantes (1). En Estados Unidos en el 2011 se encontra...

  20. Calcified renal oncocytoma

    Energy Technology Data Exchange (ETDEWEB)

    Wasserman, N.F. (Veterans Administration, Minneapolis, MN); Ewing, S.L.

    1983-10-01

    Renal oncocytoma, a neoplasm thought to derive from cells of the proximal convoluted tubules, exhibits benign clinical features. Its preoperative distinction from typical renal cell carcinoma would enable the surgeon to perform a more limited procedure. In a patient who is a poor operative candidate, surgery might be deferred. However, preoperative diagnosis has been elusive. A rare case of bilateral renal oncocytoma is reported. One of these tumors represents the first reported oncocytoma showing radiologically demonstrable calcification.

  1. Thrombospondin in Renal Disease

    OpenAIRE

    Hugo, Christian; Daniel, Christoph

    2013-01-01

    Thrombospondins (TSPs) are multifunctional matricellular glycoproteins which are involved in the regulation of angiogenesis, proliferation, apoptosis, the NO-cGMP-dependent protein kinase pathway and transforming growth factor (TGF) _ activation. The TSP family consists of 5 members, but currently only data on effects of TSP-1 and TSP-2 in renal disease are available. Both TSPs are hardly expressed within the healthy renal cortex and can be upregulated during renal disease. Using different an...

  2. Lithium and Renal Impairment

    DEFF Research Database (Denmark)

    Nielsen, René Ernst; Kessing, Lars Vedel; Nolen, Willem A

    2018-01-01

    INTRODUCTION: Lithium is established as an effective treatment of mania, of depression in bipolar and unipolar disorder, and in maintenance treatment of these disorders. However, due to the necessity of monitoring and concerns about irreversible adverse effects, in particular renal impairment......, after long-term use, lithium might be underutilized. METHODS: This study reviewed 6 large observational studies addressing the risk of impaired renal function associated with lithium treatment and methodological issues impacting interpretation of results. RESULTS: An increased risk of renal impairment...

  3. Incidental renal neoplasms

    DEFF Research Database (Denmark)

    Rabjerg, Maj; Mikkelsen, Minne Nedergaard; Walter, Steen

    2014-01-01

    On the basis of associations between tumor size, pathological stage, histological subtype and tumor grade in incidentally detected renal cell carcinoma vs symptomatic renal cell carcinoma, we discussed the need for a screening program of renal cell carcinoma in Denmark. We analyzed a consecutive...... series of 204 patients with renal tumors in 2011 and 2012. The tumors were classified according to detection mode: symptomatic and incidental and compared to pathological parameters. Eighty-nine patients (44%) were symptomatic, 113 (55%) were incidental. Information was not available in two patients...

  4. Spontaneous renal artery dissection.

    Science.gov (United States)

    John, Santhosh G; Pillai, Unnikrishnan; Vaidyan, Philip B; Ishiyama, Takaaki

    2010-01-01

    Isolated spontaneous dissection of renal arteries or its branches are extremely rare. Most cases of renal artery dissection are associated with underlying pathology of the renal arteries. We report a case of spontaneous dissection of the left main renal artery and infarction of the left kidney with positive antiphospholipid antibody. Extensive work up of the patient including imaging studies confirmed the diagnosis of SRAD. Antiphospholipid antibodies may have a role in the pathogenesis of arterial dissection by causing endothelial dysfunction. This is a first literature report.

  5. Atheroembolic renal disease

    Science.gov (United States)

    ... risk factors for atherosclerosis, including age, male gender, cigarette smoking, high blood pressure, high cholesterol and diabetes. Alternative Names Renal disease - atheroembolic; Cholesterol embolization syndrome; Atheroemboli - ...

  6. Primary renal angiosarcoma

    Directory of Open Access Journals (Sweden)

    Osmar E. Souza

    2006-08-01

    Full Text Available Primary renal Angiosarcoma is a rare neoplasm and only 24 cases have been reported in specialized literature. We describe a case of primary renal angiosarcoma in a patient presenting with hematuria, palpable abdominal mass, left flank pain and anemia. A computerized tomography of the abdomen with contrast medium showed a tumor with 15 cm diameter, in the upper pole of the left kidney, with a low-density central area, suggesting necrosis or hemorrhage. Diagnosis was given in a morphologic base and proven by an immunohistochemical study. Primary renal angiosarcoma should be included among differential diagnosis of retroperitoneal hematoma and hemorrhagic renal tumors.

  7. VENA RENAL IZQUIERDA RETRO-AÓRTICA. Retro-aortic left renal vein

    Directory of Open Access Journals (Sweden)

    Alejandro M Russo

    2016-03-01

    Full Text Available El conocimiento de la anatomía venosa del riñón y sus variaciones es esencial para realizar cualquier tipo de procedimiento en la región. Se reporta una variante del árbol venoso del riñón izquierdo, encontrado durante la disección cadavérica, la vena renal izquierda retro-aórtica. Se trató de un tronco único originado a nivel del hilio renal izquierdo que discurrió por detrás de la arteria aorta abdominal para finalizar en la vena cava inferior. La existencia de este vaso se asocia a la embriología de la vena cava inferior. Se discuten aspectos quirúrgicos, radiológicos y embriológicos de su persistencia. Otras implicancias clínicas también son comentadas. Understanding of the renal venous anatomy and its variations is essential to perform any procedure in the region. We report a variation of the left renal venous tree found during a cadaveric dissection, the retro-aortic left renal vein. It was a unique venous trunk that emerged from the left renal hilum and traveled dorsally to the abdominal aorta before reaching the inferior vena cava. The existence of this vessel is associated to the embryology of the inferior vena cava. We discuss the surgical, radiological and possible embryological aspects. Other clinical implications are also considered. 

  8. Celulitis por citomegalovirus Cytomegalovirus cellulitis

    Directory of Open Access Journals (Sweden)

    A. Ruiz Lascano

    2002-12-01

    Full Text Available Las lesiones cutáneas por citomegalovirus (CMV son infrecuentes y a menudo una manifestación tardía de una enfermedad sistémica, que generalmente anuncia un curso fatal. Comunicamos un caso de celulitis por CMV: una mujer de 70 años con trasplante renal efectuado 1 mes antes de la consulta, terapia inmunosupresora con ciclosporina A y metilprednisona. La paciente ingresó por fiebre, dolor e impotencia funcional en pierna derecha. Comprobamos la existencia de una placa de 8 por 4 cm eritematoedematosa. La tratamos con antibióticos sin mejoría, por lo que realizamos un estudio histopatológico de piel que mostró cambios citopáticos compatibles con infección por CMV. Los cultivos bacteriológicos y micológicos fueron negativos. La inmunohistoquímica específica para CMV y el estudio de reacción en cadena de la polimerasa (PCR de la biopsia de piel fueron positivas, al igual que la antigenemia. El tratamiento con ganciclovir produjo la mejoría del cuadro clínico. En la literatura revisada no hemos encontrado la celulitis como manifestación de enfermedad cutánea por CMV.Cutaneous lesions in CMV infection are rare, often a late manifestation of systemic infection, and usually herald a fatal course. A 70 year-old woman received a kidney transplantation one month before consulting and immunosuppressive therapy that included cyclosporine A and methylprednisone. She complained of fever, local pain in her right leg, and an erythematous and swelling plaque. She was treated with intravenous antibiotics without improvement. A skin biopsy was performed and the tissue obtained was sent for bacterial and fungal cultures as well as for histological examination. Cultures were negative. The biopsy showed CMV cytopathic changes. Immunoperoxidase staining was positive for CMV and polymerase chain reaction (PCR testing revealed CMV DNA. She was treated with ganciclovir with resolution of the lesion. CMV cellulitis is a rare cutaneous manifestation

  9. Renal cell carcinoma in patient with crossed fused renal ectopia

    Directory of Open Access Journals (Sweden)

    Ozgur Cakmak

    2016-01-01

    Full Text Available Primary renal cell carcinomas have rarely been reported in patients with crossed fused renal ectopia. We presented a patient with right to left crossed fused kidney harbouring renal tumor. The most frequent tumor encountered in crossed fused renal ectopia is renal cell carcinoma. In this case, partial nephrectomy was performed which pave way to preservation of the uninvolved both renal units. Due to unpredictable anatomy, careful preoperative planning and meticulous delineation of renal vasculature is essential for preservation of the uninvolved renal units.

  10. A case of renal oncocytoma

    OpenAIRE

    村本, 将俊; 内田, 豊昭; 及能, 久隆; 石田, 裕則; 宇都宮, 拓治; 頴川, 晋; 真下, 節夫; 小柴, 健

    1994-01-01

    A case of renal oncocytoma found incidentally by routine medical checkups is reported. An asymptomatic 70-year-old male was found to have a right renal mass by abdominal ultrasonography. Selective renal arteriography supported the diagnosis of renal oncocytoma with a typical appearance of "spoke-wheel" pattern. Right radical nephrectomy was performed. However, in consideration of the possibility of renal cell carcinoma. The diagnosis of renal oncocytoma was finally confirmed pathologically. T...

  11. Distal renal tubular acidosis in recurrent renal stone formers

    DEFF Research Database (Denmark)

    Osther, P J; Hansen, A B; Røhl, H F

    1989-01-01

    Renal acidification ability was examined in 90 recurrent renal stone formers, using fasting morning urinary pH levels followed by a short ammonium chloride loading test in subjects with pH levels above 6.0. Fifteen patients (16.6%) revealed a distal renal tubular acidification defect: one patient...... (1.1%) had complete distal renal tubular acidosis and 14 (15.5%) incomplete distal renal tubular acidosis. Our results confirm that distal renal tubular acidification defects are associated with a more severe form of stone disease and make distal renal tubular acidosis one of the most frequent...... metabolic disturbances in renal stone formers. Distal renal tubular acidosis (dRTA) was relatively more common in female stone formers and most often found in patients with bilateral stone disease (36%). Since prophylactic treatment in renal stone formers with renal acidification defects is available...

  12. Distal renal tubular acidosis in recurrent renal stone formers

    DEFF Research Database (Denmark)

    Osther, P J; Hansen, A B; Røhl, H F

    1989-01-01

    (1.1%) had complete distal renal tubular acidosis and 14 (15.5%) incomplete distal renal tubular acidosis. Our results confirm that distal renal tubular acidification defects are associated with a more severe form of stone disease and make distal renal tubular acidosis one of the most frequent...... metabolic disturbances in renal stone formers. Distal renal tubular acidosis (dRTA) was relatively more common in female stone formers and most often found in patients with bilateral stone disease (36%). Since prophylactic treatment in renal stone formers with renal acidification defects is available......Renal acidification ability was examined in 90 recurrent renal stone formers, using fasting morning urinary pH levels followed by a short ammonium chloride loading test in subjects with pH levels above 6.0. Fifteen patients (16.6%) revealed a distal renal tubular acidification defect: one patient...

  13. Cancer - renal pelvis or ureter

    Science.gov (United States)

    ... Kidney cancer - renal pelvis; Ureter cancer Images Kidney anatomy References National Cancer Institute. PDQ transitional cell cancer of the renal pelvis and ureter treatment. Bethesda, MD: National Cancer ...

  14. Renal dysfunction in cirrhosis.

    Science.gov (United States)

    Urrunaga, Nathalie H; Mindikoglu, Ayse L; Rockey, Don C

    2015-05-01

    Renal dysfunction causes significant morbidity in cirrhotic patients. Diagnosis is challenging because it is based on serum creatinine, which is used to calculate estimated glomerular filtration rate, which itself is not an ideal measure of renal function in patients with cirrhosis. Finding the exact cause of renal injury in patients with cirrhosis remains problematic due to the limitations of the current diagnostic tests. The purpose of this review is to highlight studies used to diagnose renal dysfunction in patients with renal dysfunction and review current treatments. New diagnostic criteria and classification of renal dysfunction, especially for acute kidney injury (AKI), have been proposed in hopes of optimizing treatment and improving outcomes. New biomarkers that help to differentiate structural from functional AKI in cirrhotic patients have been developed, but require further investigation. Vasoconstrictors are the most commonly recommended treatment of hepatorenal syndrome (HRS). Given the high mortality in patients with type 1 HRS, all patients with HRS should be evaluated for liver transplantation. When renal dysfunction is considered irreversible, combined liver-kidney transplantation is advised. Development of new biomarkers to differentiate the different types of AKI in cirrhosis holds promise. Early intervention in cirrhotic patients with renal dysfunction offers the best hope of improving outcomes.

  15. Cicatriz renal: factores de riesgo relacionados con infección urinaria Renal scar: risk factors related to urinary infection

    Directory of Open Access Journals (Sweden)

    Lourdes María Pérez Clemente

    2007-06-01

    Full Text Available La infección urinaria es una de las infecciones bacterianas más frecuente en la niñez, superada solamente por las infecciones respiratorias. En algunos casos, puede causar cicatrices renales que pueden inducir complicaciones futuras, como la hipertensión arterial y enfermedad renal crónica. Los métodos de diagnóstico por imagen en los niños tienen como objetivo identificar a los pacientes en riesgo de desarrollar cicatrices renales o daño renal permanente, o de prevenir la progresión del daño renal preexistente. Se evaluaron retrospectivamente los datos clínicos de 100 niños con diagnóstico de infección urinaria, a los cuales se les realizó gammagrafía renal con ácido dimercaptosuccínico (DMSA. Se correlacionó la presencia de cicatriz renal con la edad, sexo, número de episodios de infección urinaria y presencia de reflujo vesicoureteral. Se demostró que todo niño con infección urinaria, independientemente del sexo, corre el riesgo de desarrollar cicatriz renal, el cual aumenta con la presencia de reflujo vesicoureteral, infecciones recurrentes y en la medida en que aumenta la edad. Por ello sugerimos estudiar, mediante ultrasonido, cistografía y gammagrafía con DMSA marcado con tecnecio 99 (Tc99m-DMSA, a todo niño con infección urinaria, para detectar oportunamente a quienes están en riesgo de desarrollar cicatriz renal o daño renal permanente.Urinary infection is one of the most common bacterial infections in childhood after respiratory infections. In some cases, it can cause renal scars that may lead to future complications like blood hypertension and chronic renal disease. The diagnostic imaging methods for children are aimed at identifying those patients at risk of developing renal scars or a permanent renal damage, and preventing the progression of pre-existing renal damage. Clinical data from 100 children diagnosed with urinary infection, who had been performed a renal DMSA scintigraphy, were retrospectively

  16. Infecciones genitales por VPH tratadas por microinmunoterapia

    National Research Council Canada - National Science Library

    Jacques Grauwet, Diego

    2011-01-01

    ... genitales por VPH tratadas por microinmunoterapia Diego Jacques Grauwet Médico ginecólogo y homeópata, Madrid, España Recibido el 30 de mayo de 2010; aceptado el 10 de septiembre de 2011 Correo...

  17. Eligibility for renal denervation

    DEFF Research Database (Denmark)

    Persu, Alexandre; Jin, Yu; Baelen, Marie

    2014-01-01

    Based on the SYMPLICITY studies and CE (Conformité Européenne) certification, renal denervation is currently applied as a novel treatment of resistant hypertension in Europe. However, information on the proportion of patients with resistant hypertension qualifying for renal denervation after...... a thorough work-up and treatment adjustment remains scarce. The aim of this study was to investigate the proportion of patients eligible for renal denervation and the reasons for noneligibility at 11 expert centers participating in the European Network COordinating Research on renal Denervation in treatment......-resistant hypertension (ENCOReD). The analysis included 731 patients. Age averaged 61.6 years, office blood pressure at screening was 177/96 mm Hg, and the number of blood pressure-lowering drugs taken was 4.1. Specialists referred 75.6% of patients. The proportion of patients eligible for renal denervation according...

  18. Renal vascular changes in renal disease independent of hypertension

    NARCIS (Netherlands)

    Bos, W. J.; Demircan, M. M.; Weening, J. J.; Krediet, R. T.; van der Wal, A. C.

    2001-01-01

    INTRODUCTION: Cardiovascular disease is common in patients with renal disease, but little is known about the effect of renal disease and loss of renal function on vascular morphology. Intima proliferation of small renal arteries, which correlates with atherosclerosis in the aorta, is sometimes

  19. Renal replacement therapy after cardiac surgery; renal function recovers

    DEFF Research Database (Denmark)

    Steinthorsdottir, Kristin Julia; Kandler, Kristian; Agerlin Windeløv, Nis

    2013-01-01

    To assess renal outcome in patients discharged from hospital following cardiac surgery-associated acute kidney injury (CSA-AKI) with need for renal replacement therapy.......To assess renal outcome in patients discharged from hospital following cardiac surgery-associated acute kidney injury (CSA-AKI) with need for renal replacement therapy....

  20. La fragilidad en el anciano con enfermedad renal crónica

    Directory of Open Access Journals (Sweden)

    Maria Eugenia Portilla Franco

    2016-11-01

    La fragilidad puede ser una situación reversible, por lo que su estudio en el paciente con enfermedad renal crónica es de especial interés. Este artículo tiene por objeto describir las interrelaciones existentes entre envejecimiento, fragilidad y enfermedad renal crónica a la luz de la bibliografía pertinente más relevante y reciente publicada.

  1. Renal Preservation Therapy for Renal Cell Carcinoma

    Directory of Open Access Journals (Sweden)

    Yichun Chiu

    2012-01-01

    Full Text Available Renal preservation therapy has been a promising concept for the treatment of localized renal cell carcinoma (RCC for 20 years. Nowadays partial nephrectomy (PN is well accepted to treat the localized RCC and the oncological control is proved to be the same as the radical nephrectomy (RN. Under the result of well oncological control, minimal invasive method gains more popularity than the open PN, like laparoscopic partial nephrectomy (LPN and robot assisted laparoscopic partial nephrectomy (RPN. On the other hand, thermoablative therapy and cryoablation also play an important role in the renal preservation therapy to improve the patient procedural tolerance. Novel modalities, but limited to small number of patients, include high-intensity ultrasound (HIFU, radiosurgery, microwave therapy (MWT, laser interstitial thermal therapy (LITT, and pulsed cavitational ultrasound (PCU. Although initial results are encouraging, their real clinical roles are still under evaluation. On the other hand, active surveillance (AS has also been advocated by some for patients who are unfit for surgery. It is reasonable to choose the best therapeutic method among varieties of treatment modalities according to patients' age, physical status, and financial aid to maximize the treatment effect among cancer control, patient morbidity, and preservation of renal function.

  2. Renal failure (chronic).

    Science.gov (United States)

    Clase, Catherine

    2011-05-25

    Continued progression of renal failure will lead to renal function too low to sustain healthy life. In developed countries, such people will be offered renal replacement therapy in the form of dialysis or renal transplantation. Requirement for dialysis or transplantation is termed end-stage renal disease (ESRD). We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of drug treatments used to reduce progression rate of chronic renal failure? What are the effects of lifestyle changes used to reduce progression rate of chronic renal failure? We searched: Medline, Embase, The Cochrane Library, and other important databases up to October 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). We found 44 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. In this systematic review we present information relating to the effectiveness and safety of the following interventions: angiotensin II receptor antagonists, angiotensin-converting enzyme (ACE) inhibitors (with or without angiotensin II receptor antagonists), exercise, erythropoiesis-stimulating agents, fibrates, lowering blood pressure below usual targets, nicotinates, psychoeducational intervention, smoking cessation, sodium (dietary), statins, structured programmes to achieve therapeutic goals, and targeted lowering of albuminuria/proteinuria.

  3. Chromophobe Renal Cell Carcinoma.

    Directory of Open Access Journals (Sweden)

    Jyotsna Vijaykumar Wader

    2013-04-01

    Full Text Available Renal cell carcinoma is the most common neoplasm of the kidney comprised of different histological variants. Chromophobe renal cell carcinoma (ChRCC is a rare subtype of renal cell carcinoma (RCC mainly diagnosed in the sixth decade of life. It is important to identify this entity because it has significantly better prognosis than the clear cell (conventional and papillary renal cell carcinomas. The chromophobe renal cell carcinoma should be differentiated from oncocytoma and clear cell carcinoma. We report a case of a 70 year-old male who presented with a six month history of hematuria, left sided flank pain and a palpable non-tender lump in the left lumbar region. On radiology, the possibility of a left renal neoplasm was raised. A left radical nephrectomy was done and histopathological diagnosis of Type 2 (mixed chromophobe renal cell carcinoma was given. We present this case owing to its relative rarity of incidence, difficulties encountered and differential diagnoses to be considered during diagnosis as the prognosis and management protocols differ with different variants.

  4. Perioperative acute renal failure.

    LENUS (Irish Health Repository)

    Mahon, Padraig

    2012-02-03

    PURPOSE OF REVIEW: Recent biochemical evidence increasingly implicates inflammatory mechanisms as precipitants of acute renal failure. In this review, we detail some of these pathways together with potential new therapeutic targets. RECENT FINDINGS: Neutrophil gelatinase-associated lipocalin appears to be a sensitive, specific and reliable biomarker of renal injury, which may be predictive of renal outcome in the perioperative setting. For estimation of glomerular filtration rate, cystatin C is superior to creatinine. No drug is definitively effective at preventing postoperative renal failure. Clinical trials of fenoldopam and atrial natriuretic peptide are, at best, equivocal. As with pharmacological preconditioning of the heart, volatile anaesthetic agents appear to offer a protective effect to the subsequently ischaemic kidney. SUMMARY: Although a greatly improved understanding of the pathophysiology of acute renal failure has offered even more therapeutic targets, the maintenance of intravascular euvolaemia and perfusion pressure is most effective at preventing new postoperative acute renal failure. In the future, strategies targeting renal regeneration after injury will use bone marrow-derived stem cells and growth factors such as insulin-like growth factor-1.

  5. Midterm renal functions following acute renal infarction

    Directory of Open Access Journals (Sweden)

    Sakir Ongun

    2015-10-01

    Full Text Available The aim of this study was to explore clinical features of renal infarction (RI that may have a role in diagnosis and treatment in our patient cohort and provide data on midterm renal functions. Medical records of patients with diagnosis of acute RI, established by contrast enhanced computed tomography (CT and at least 1 year follow-up data, who were hospitalized in our clinic between 1998 and 2012 were retrospectively reviewed; including descriptive data, clinical signs and symptoms, etiologic factors, laboratory findings, and prescribed treatments. Patients with solitary infarct were treated with acetylsalicylic acid (ASA only, whereas patients with atrial fibrillation (AF or multiple or global infarct were treated with anticoagulants. Estimated Glomerular Filtration Rate (eGFR referring to renal functions was determined by the Modification of Diet in Renal Disease (MDRD formula. Twenty-seven renal units of 23 patients with acute RI were identified. The mean age was 59.7 ± 15.7 years. Fourteen patients (60.8% with RI had atrial fibrillation (AF as an etiologic factor of which four had concomitant mesenteric ischemia at diagnosis. At presentation, 20 patients (86.9% had elevated serum lactate dehydrogenase (LDH, 18 patients (78.2% had leukocytosis, and 16 patients (69.5% had microscopic hematuria. Two patients with concomitant mesenteric ischemia and AF passed away during follow up. Mean eGFR was 70.8 ± 23.2 mL/min/1.73 m2 at admission and increased to 82.3 ± 23.4 mL/min/1.73 m2 at 1 year follow up. RI should be considered in patients with persistent flank or abdominal pain, particularly if they are at high risk of thromboembolism. Antiplatelet and/or anticoagulant drugs are both effective treatment options according to the amplitude of the infarct for preserving kidney functions.

  6. Renal Branch Artery Stenosis

    DEFF Research Database (Denmark)

    Andersson, Zarah; Thisted, Ebbe; Andersen, Ulrik Bjørn

    2017-01-01

    Renovascular hypertension is a common cause of pediatric hypertension. In the fraction of cases that are unrelated to syndromes such as neurofibromatosis, patients with a solitary stenosis on a branch of the renal artery are common and can be diagnostically challenging. Imaging techniques...... that perform well in the diagnosis of main renal artery stenosis may fall short when it comes to branch artery stenosis. We report 2 cases that illustrate these difficulties and show that a branch artery stenosis may be overlooked even by the gold standard method, renal angiography....

  7. Renal oncocytoma: new observations

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, M.J.; Hartman, D.S.; Friedman, A.C.; Sherman, J.L.; Lautin, E.M.; Pyatt, R.S.; Ho, C.K.; Csere, R.; Fromowitz, F.B.

    1984-10-01

    Renal oncocytomas are uncommon, benign tumors that can be treated by local incision or heminephrectomy; their preoperative differentiation from renal cell carcinoma, treated by radical nephrectomy, would be invaluable. A particularly important finding, a central scar, not stressed in previous reports, is frequently demonstrated by CT examination. The authors evaluated radiographic studies of 18 pathologically confirmed cases of oncocytoma and compared findings with results of CT, sonography, and angiogrpahy studies of 18 renal cell carcinoma cases. Oncocytomas can be suggested if a stellate scar is identified within an otherwise homogeneous tumor on ultrasound (US) and CT; if the mass appears homogeneous but no scar is present, angiography should be performed.

  8. Biomarcadores da injúria renal aguda

    Directory of Open Access Journals (Sweden)

    Luis Alberto Batista Peres

    2013-09-01

    Full Text Available A creatinina continua a ser o padrão laboratorial para diagnóstico da injúria renal aguda (IRA. Esforços para prevenção da nefrotoxicidade foram prejudicados pelo atraso no diagnóstico da IRA por critérios utilizando somente a creatinina como marcador, havendo, por isso, grande interesse em identificar mais precocemente biomarcadores confiáveis. Além disso, o tratamento precoce da IRA pode ser correlacionado com um melhor prognóstico e a identificação de biomarcadores para um diagnóstico precoce pode melhorar a eficácia de estratégia terapêutica. Portanto, torna-se imperativo encontrar biomarcadores que possam estratificar corretamente o grau de lesão renal e o risco de desenvolver doença renal crônica (DRC. Aqui, nós revisamos as principais características dos emergentes biomarcadores em nefrologia.

  9. Infarto renal segmentario y factor V de Leiden

    National Research Council Canada - National Science Library

    Cabral Ribeiro, Jorge; Sousa, Lemos; Calaza, Carlos; Santos, Américo

    2009-01-01

    ... sólo se explican por una trombofília hereditaria o adquirida. Los autores presentan un caso de infarto renal segmentario asociado al factor V de Leiden. Método/Resultados: Varón de 48 años que presenta...

  10. Double renal artery in cat/ Artéria renal dupla em gato

    Directory of Open Access Journals (Sweden)

    Marcelo Abidu-Figueiredo

    solução de formaldeído a 10% e teve o seu sistema arterial preenchido com látex corado. Observou-se que o rim esquerdo foi suprido por duas artérias renais, de diferente topografia e arranjo, caracterizando duplicidade da artéria renal.

  11. Hereditary Renal Diseases.

    Science.gov (United States)

    Mehta, Lakshmi; Jim, Belinda

    2017-07-01

    Hereditary kidney disease comprises approximately 10% of adults and nearly all children who require renal replacement therapy. Technologic advances have improved our ability to perform genetic diagnosis and enhanced our understanding of renal and syndromic diseases. In this article, we review the genetics of renal diseases, including common monogenic diseases such as polycystic kidney disease, Alport syndrome, and Fabry disease, as well as complex disorders such as congenital anomalies of the kidney and urinary tract. We provide the nephrologist with a general strategy to approach hereditary disorders, which includes a discussion of commonly used genetic tests, a guide to genetic counseling, and reproductive options such as prenatal diagnosis or pre-implantation genetic diagnosis for at-risk couples. Finally, we review pregnancy outcomes in certain renal diseases. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Renal cell carcinoma

    Science.gov (United States)

    ... kidney Patient Instructions Kidney removal - discharge Images Kidney anatomy Kidney tumor - CT scan Kidney metastases, CT scan Kidney - blood and urine flow References Campbell SC, Lane BR. Malignant renal tumors. In: Wein AJ, Kavoussi LR, Partin AW, ...

  13. Primary renal synovial sarcoma

    Directory of Open Access Journals (Sweden)

    Girish D. Bakhshi

    2012-03-01

    Full Text Available Primary Renal Sarcoma is rare tumor comprising only 1% of all renal tumours. Synovial sarcomas are generally deep-seated tumors arising in the proximity of large joints of adolescents and young adults and account for 5-10% of all soft tissue tumours. Primary synovial sarcoma of kidney is rare and has poor prognosis. It can only be diagnosed by immunohistochemistry. It should be considered as a differential in sarcomatoid and spindle cell tumours. We present a case of 33-year-old female, who underwent left sided radical nephrectomy for renal tumour. Histopathology and genetic analysis diagnosed it to be primary renal synovial sarcoma. Patient underwent radiation therapy and 2 years follow up is uneventful. A brief case report with review of literature is presented.

  14. Dopamins renale virkninger

    DEFF Research Database (Denmark)

    Olsen, Niels Vidiendal

    1990-01-01

    is frequently employed in cases of acute oliguric renal failure but the results available concerning the therapeutic effect are frequently retrospective and uncontrolled. The results suggest that early treatment with 1-3 micrograms/kg/min dopamine combined with furosemide can postpone or possibly render...... are possible not exclusively secondary to alterations in the renal haemodynamics but may also be due to specific tubular effects. Recent investigations have revealed that dopamine does not increase RBF and GFR in patients with chronic renal failure if GFR is less than 60 ml/minute. Dopamine in low doses......Dopamine is an endogenic catecholamine which, in addition to being the direct precursor of noradrenaline, has also an effect on peripheral dopaminergic receptors. These are localized mainly in the heart, splanchnic nerves and the kidneys. Dopamine is produced in the kidneys and the renal metabolism...

  15. Renal protection in diabetes

    DEFF Research Database (Denmark)

    Parving, H H; Tarnow, L; Rossing, P

    1996-01-01

    BACKGROUND: The combination of diabetes and hypertension increases the chances of progressive renal disorder and, ultimately, renal failure. Roughly 40% of all diabetics, whether insulin-dependent or not, develop diabetic nephropathy. Diabetic nephropathy is the single most important cause of end......-stage renal disease in the Western world and accounts for more than a quarter of all end-stage renal diseases. Diabetic nephropathy is a major cause of increased morbidity and mortality in diabetic patients. Increased arterial blood pressure is an early and common phenomenon in incipient and overt diabetic...... nephropathy. The relationship between arterial blood pressure and diabetic nephropathy is a complex one, with diabetic nephropathy increasing blood pressure and blood pressure accelerating the course of nephropathy. OVERVIEW: Calcium antagonists antagonize preglomerular vasoconstriction. Additional putative...

  16. Renal function after trauma.

    Science.gov (United States)

    World, Michael J

    2013-06-01

    The lack of need for immediate renal replacement treatment for military trauma victims suggests that the current policy of restricting operational deployment of those Service personnel with active inflammatory renal disease and significantly impaired renal function, combined with good prehospital care for all trauma casualties, is probably correct. No published estimates of renal function in civilian or military trauma victims in the earliest period following injury have been retrieved. The purpose of the present retrospective study was to assess the renal function of military trauma victims on arrival in the Emergency Department of the field hospital. The case records of 287 military trauma casualties with severe injury (New Injury Severity Score, NISS≥16) were retrospectively reviewed to assess renal function by calculating estimated glomerular filtration rate (eGFR) using the serum creatine concentration obtained immediately on arrival in the Emergency Department of the field hospitals in Iraq and Afghanistan, 2005-2009. Correlations were attempted between eGFR and other clinical and laboratory variables. Hospital case notes recording management following repatriation were retrieved in 221/287 (77%) cases. None had required immediate renal support in the field. Serum creatine concentration on arrival in the field hospital with demographic data permitting calculation of eGFR was recorded in 158 cases. Median eGFR=76 ml/min/1.73 m(2) (range=43-144). Statistically significant correlations were found among eGFR and pulse rate (r=-0.3, p=0.0002), body temperature (r=0.24, p=0.01) and mean arterial pressure (r=0.2, p=0.02). No statistically significant correlation was found among eGFR and NISS, white cell count, or respiration rate. A stepwise multivariate regression analysis of 106 cases suggested that the best combination of clinical observations to predict renal function were pulse rate and body temperature but the prediction was overoptimistic at lower e

  17. OBSTETRIC RENAL FAILURE

    Directory of Open Access Journals (Sweden)

    Rajeshwari

    2015-11-01

    Full Text Available Renal failure in obstetrics is rare but important complication, associated with significant mortality and long term morbidity.1,2 It includes acute renal failure due to obstetrical complications or due to deterioration of existing renal disease. AIMS AND OBJECTIVES: To evaluate the etiology and outcome of renal failure in obstetric patients. METHODS: We prospectively analyzed 30 pregnant and puerperal women with acute renal failure or pre-existing renal disease developing renal failure during pregnancy between November 2007 to sep-2009. Patients who presented/developed ARF during the hospital stay were included in this study. RESULTS: Among 30 patients, mean age was 23 years and 33 years age group. 12 cases (40% patients were primigravidae and 9(30% patients were multigravidae and 9 cases (30% presented in post-partum period. Eighteen cases (60% with ARF were seen in third trimester, followed by in postpartum period 9 cases (30%. Most common contributing factors to ARF were Pre-eclampsia, eclampsia and HELLP syndrome 60%, sepsis 56.6%, post abortal ARF 10%. DIC 40%. Haemorrhage as the aetiology for ARF was present 46%, APH in 20% and PPH in 26.6%. The type of ARF was renal in (63% and prerenal (36%; Oliguric seen in 10 patients (33% and high mortality (30%. Among the 20 pregnant patients with ARF, The average period of gestation was 33±2 weeks (30 -36 weeks, 5 cases (25% presented with intrauterine fetal demise and 18 cases (66% had preterm vaginal delivery and 2 cases (10% had induced abortion. And the average birth weight was 2±0.5 kg (1.5 kg. Eight cases (26% required dialysis. 80% of patients recovered completely of renal functions. 63% patients recovered without renal replacement therapy whereas 17% required dialysis. the maternal mortality was 20%, the main reason for mortality was septic shock and multi organ dysfunction (66%. CONCLUSION: ARF related pregnancy was seen commonly in the primigravidae and in the third trimester, the most

  18. Renal papillary necrosis

    Directory of Open Access Journals (Sweden)

    Stephen A. Geller

    2013-12-01

    Full Text Available In 1877, Dr. Nikolaus Friedreich (1825-1882; student of Virchow who became Professor of Pathology at Heidelberg and who also described Friedreich’s ataxia first described renal papillary necrosis (RPN in patients with prostatic hypertrophy and secondary hydronephrosis. Thereafter in 1937, Froboese and Günther emphasized the association of this entity with diabetes mellitus. These authors also observed renal papillary necrosis in cases of urinary tract obstruction even in the absence of diabetes mellitus.

  19. Exercise and Renal Function

    OpenAIRE

    Masato, SUZUKI; Japan Society of Exercise and Sports Physiology; Department of Laboratory Medicine, The Jikeidai University School of Medicine

    1996-01-01

    Research on renal function during exercise is very rare in the sports medicine area because it has no direct bearing on the performance of exercise. However, the kidneys play an important role in maintaining a constant internal state, which, when disturbed by exercise in a hot environment, is normalized by means of enhanced conservation of water and electrolytes by the kidneys. It is the purpose of this article to review the previous literature, to relate some of our findings on renal functio...

  20. Renal pathology in reptiles.

    Science.gov (United States)

    Zwart, Peernel

    2006-01-01

    The class of Reptilia varies widely. Both the gross morphology and microscopic anatomy of the kidneys are specific for each species. In each species of reptile, the physiology of the renal system has adapted to the specific conditions of life, including, among other factors, the type of food, environmental temperature, and the availability of water. The pathology of the kidneys in reptiles has been poorly studied, but in recent years a number of investigators have specifically studied reptilian renal pathology.

  1. Neonatal renal cystic diseases.

    Science.gov (United States)

    Khare, Anshika; Krishnappa, Vinod; Kumar, Deepak; Raina, Rupesh

    2017-08-02

    Neonatal renal cystic diseases have a great impact on the morbidity and mortality of the affected neonates and infants. A good insight into the pathophysiology, diagnosis and treatment options of various neonatal renal cystic diseases aid in early diagnosis and intervention, thereby preventing complications. PubMed search was done for articles on "neonatal renal cystic diseases" and relevant publications including reviews were considered for our article. Both hereditary and nonhereditary causes of cystic kidney diseases can result in severe morbidity and mortality. The main diagnostic modality is ultrasound imaging and most of the neonatal renal cystic diseases are detected during prenatal ultrasound screening. Commonly encountered neonatal renal cystic diseases are autosomal dominant polycystic kidney disease, autosomal recessive polycystic kidney disease and multicystic dysplastic kidney. A thorough knowledge of various renal cystic diseases can be of extreme prognostic value. Physicians should be aware of the impact of early diagnosis and intervention on the lives of those affected. Further research about treatment of these diseases is ongoing and can result in breakthrough therapies for these patients.

  2. Hereditary Renal Cancer Syndromes

    Science.gov (United States)

    Haas, Naomi B.

    2013-01-01

    Inherited susceptibility to kidney cancer is a fascinating and complex topic. Our knowledge about types of genetic syndromes associated with an increased risk of disease is continually expanding. Currently, there are 10 syndromes associated with an increased risk of all types of renal cancer, which are reviewed herein. Clear cell renal cancer is associated with von Hippel Lindau disease, chromosome 3 translocations, PTEN hamartomatous syndrome and mutations in BAP1, as well as several of the genes encoding the proteins comprising the succinate dehydrogenase complex (SDHB/C/D). Type 1 papillary renal cancers arise in conjunction with germline mutations in MET and type 2 as part of Hereditary Leiomyomatosis and Renal Cell Cancer (FH mutations). Chromophone and oncocytic renal cancers are predominantly associated with Birt Hogg Dubé syndrome. Angiomyolipomas are commonly and their malignant counterpart epitheliod angiomyolipomas rarely are found in patients with Tuberous Sclerosis Complex. The targeted therapeutic options for the renal cancer associated with these diseases are just starting to expand, and are an area of active clinical research. PMID:24359990

  3. Targeting Strategies for Renal Cell Carcinoma: From Renal Cancer Cells to Renal Cancer Stem Cells

    OpenAIRE

    Yuan, Zhi-xiang; Mo, Jingxin; Zhao, Guixian; Shu, Gang; Fu, Hua-Lin; Wei ZHAO

    2016-01-01

    Renal cell carcinoma (RCC) is a common form of urologic tumor that originates from the highly heterogeneous epithelium of renal tubules. Over the last decade, targeting therapies to renal cancer cells have transformed clinical care for RCC. Recently, it was proposed that renal cancer stem cells (CSCs) isolated from renal carcinomas were responsible for driving tumor growth and resistance to conventional chemotherapy and radiotherapy, according to the theory of CSCs; this has provided the rati...

  4. Intoxicación ocupacional por mercurio

    OpenAIRE

    Augusto V. Ramírez

    2008-01-01

    El mercurio, metal pesado ampliamente utilizado por el hombre, es muy tóxico; produce daño al sistema nervioso central, perturbaciones del comportamiento y lesiones renales. Se acumula en todos los seres vivos y no es esencial para ningún proceso biológico. La toxicidad del mercurio está directamente relacionada con su estado químico. El metilmercurio es la forma más dañina, con efectos neurotóxicos en adultos y en fetos de madres expuestas. El mercurio metálico no es menos tóxico. Las sales ...

  5. Midterm renal functions following acute renal infarction.

    Science.gov (United States)

    Ongun, Sakir; Bozkurt, Ozan; Demir, Omer; Cimen, Sertac; Aslan, Guven

    2015-10-01

    The aim of this study was to explore clinical features of renal infarction (RI) that may have a role in diagnosis and treatment in our patient cohort and provide data on midterm renal functions. Medical records of patients with diagnosis of acute RI, established by contrast enhanced computed tomography (CT) and at least 1 year follow-up data, who were hospitalized in our clinic between 1998 and 2012 were retrospectively reviewed; including descriptive data, clinical signs and symptoms, etiologic factors, laboratory findings, and prescribed treatments. Patients with solitary infarct were treated with acetylsalicylic acid (ASA) only, whereas patients with atrial fibrillation (AF) or multiple or global infarct were treated with anticoagulants. Estimated Glomerular Filtration Rate (eGFR) referring to renal functions was determined by the Modification of Diet in Renal Disease (MDRD) formula. Twenty-seven renal units of 23 patients with acute RI were identified. The mean age was 59.7 ± 15.7 years. Fourteen patients (60.8%) with RI had atrial fibrillation (AF) as an etiologic factor of which four had concomitant mesenteric ischemia at diagnosis. At presentation, 20 patients (86.9%) had elevated serum lactate dehydrogenase (LDH), 18 patients (78.2%) had leukocytosis, and 16 patients (69.5%) had microscopic hematuria. Two patients with concomitant mesenteric ischemia and AF passed away during follow up. Mean eGFR was 70.8 ± 23.2 mL/min/1.73 m(2) at admission and increased to 82.3 ± 23.4 mL/min/1.73 m(2) at 1 year follow up. RI should be considered in patients with persistent flank or abdominal pain, particularly if they are at high risk of thromboembolism. Antiplatelet and/or anticoagulant drugs are both effective treatment options according to the amplitude of the infarct for preserving kidney functions. Copyright © 2015. Published by Elsevier Taiwan.

  6. Láser, luz pulsada, radiofrecuencia y otras fuentes de energía: ¿complemento ocasional a la Cirugía Plástica? Laser, IPL (Intense Pulsed light, radiofrequency and other energy sources: Occasional complement for Plastic Surgery?

    Directory of Open Access Journals (Sweden)

    R. García Pumarino Santofimia

    2008-03-01

    Full Text Available Las consultas de Cirugía Plástica se están llenando de pacientes con expectativas crecientes acerca de los resultados de los tratamientos con distintas fuentes de energía. El objetivo es conseguir un elevado índice de beneficio cosmético en el mínimo número de sesiones y con un tiempo breve de recuperación. Los tres elementos sobre los que podemos trabajar son el soporte, la textura y las alteraciones pigmentarias de la piel. Los sistemas de luz y de radiofrecuencia permiten combinar distintos niveles de tratamiento, como son la dermis profunda, la dermis papilar y la epidermis y constituyen un complemento a los procedimientos quirúrgicos, aportando un concepto "biológico" al estimular la regeneración y la neocolagenogénesis. En este artículo se describen los fundamentos de estos tratamientos complementarios que son de obligado conocimiento para los cirujanos plásticos.Plastic Surgery offices are currently full of patients who have growing expectations about the outcome of the treatments made with different energy sources. The aim is to get a high cosmetic benefit index with the lowest number of sessions and recovery time. The three elements we can work with are tone, texture and pigmentary skin disorders. The light and radiofrequency systems allow the combination of different treatment levels, such as deep dermis, papillary dermis and epidermis. These systems represent a complement for the surgical procedures, providing a "biological" concept as they stimulate the tissue regeneration and the neocollagenosis. In this article we describe the fundamentals of these complementary treatments for plastic surgeons.

  7. [Sarcomatoid renal cell carcinoma].

    Science.gov (United States)

    Arnoux, V; Lechevallier, E; Pamela, A; Long, J-A; Rambeaud, J-J

    2013-06-01

    The objective was to perform a systematic review of literature concerning epidemiology, clinical and biological data, prognosis and therapy of sarcomatoid renal cell carcinomas. Data on sarcomatoid renal cell carcinomas have been sought by querying the server Medline with MeSH terms following or combination of them: "renal carcinoma", "renal cell carcinoma," "renal cancer", "sarcomatoid" "sarcomatoid transformation" and "sarcomatoid differentiation." The articles obtained were selected according to their methodology, the language in English or French, the relevance and the date of publication. Twenty papers were selected. According to the literature, a sarcomatoid contingent can be observed in all subtypes of renal cell carcinomas, with a frequency of 1 to 15% of cases. The median age at diagnosis was 60 years with a majority of symptomatic patients (90%), mainly with abdominal pain and hematuria. These tumors were often found in patients with locally advanced or metastatic (45-77%). The imaging was not specific for the diagnosis and biopsy had a low sensitivity for identifying a sarcomatoid contingent. The treatment was based on a combination of maximal surgical resection whenever possible and systemic therapy for metastastic disease. Pathological data often showed large tumors, Furhman 4 grades, combined biphasic carcinomatous contingent (clear cell carcinoma in most cases) and sarcomatoid. Genetically, there was no specific abnormality but a complex association of chromosomal additions and deletions. The prognosis was pejorative with a specific median survival of 5 to 19 months without any impact of the sarcomatoid contingent rate. Sarcomatoid renal cell carcinoma is a form not to ignore despite its rarity. Mainly symptomatic and discovered at an advanced stage, it has a poor prognosis, requiring multidisciplinary management quickly and correctly. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  8. Idiopathic renal replacement lipomatosis: A rare renal pseudo tumor

    Directory of Open Access Journals (Sweden)

    Shailja P Wahal

    2014-01-01

    Full Text Available Renal replacement lipomatosis (RRL is a rare condition that occurs as an end result of renal atrophy or destruction of renal parenchyma by excessive lipomatous tissue in renal sinus and perinephric space. We report a case of RRL presenting as a right renal mass clinically. Intra-venous pyelography and renal scan revealed a left non-functioning kidney. A left nephrectomy was performed. After histopathological examination and extensive literature search, a diagnosis of RRL was given. In majority of cases, it is associated with renal calculi. Idiopathic variety is not common. It is a rare entity and the diagnosis may be missed due to lack of experience. It has to be differentiated from other fat-containing tumors such as renal lipoma, xanthogranulomatous pyelonephritis, angiomyolipoma and liposarcoma.

  9. Renal Infarction Caused by Isolated Spontaneous Renal Artery Intramural Hematoma.

    Science.gov (United States)

    Park, Sihyung; Lee, Ga Hee; Jin, Kyubok; Park, Kang Min; Kim, Yang Wook; Park, Bong Soo

    2015-11-24

    Acute renal infarction is an uncommon condition resulting from an obstruction or a decrease in renal arterial blood flow. Isolated spontaneous renal artery intramural hematoma is a rare cause of renal infarction. A 46-year-old healthy man presented to our emergency room because of sudden onset of severe right flank pain. An enhanced abdominal computed tomography scan showed a low-attenuated lesion in the lateral portion of the right kidney but no visible thromboembolisms in the main vessels. Computed tomography angiography revealed acute infarction resulting from intramural hematoma of the anterior segmental artery of the right kidney, with distal occlusion. The rarity and non-specific clinical presentation of renal infarction often lead to a delayed diagnosis that may result in impaired renal function. Clinical suspicion is important in the early diagnosis, and intramural hematoma of the renal artery should be considered the cause of renal infarction even in healthy patients without predisposing factors.

  10. Cryoablation of Renal Angiomyolipoma

    DEFF Research Database (Denmark)

    Makki, Ahmad; Graumann, Ole; Hoyer, Soren

    2017-01-01

    BACKGROUND: Small series have reported that cryoablation (CA) is a safe and feasible minimally invasive nephron-sparing alternative for the treatment of renal angiomyolipomas (renal AMLs). The aim of the present study was to investigate the safety and efficacy of CA in patients with renal AML....... MATERIALS AND METHODS: A retrospective review of 19 renal AML lesions treated with CA at Aarhus University Hospital, Denmark, over a 5-year period. RESULTS: The treatment was performed as laparoscopy-assisted CA on 7 lesions, and in the remaining 12 lesions CA was performed as a percutaneous ultrasound...... 13). Mean maximum tumor volume was reduced from 50.1 cm(3) (IQR 53.3) to 12.2 cm(3) (IQR 14.1), p = 0.05. No patients presented with retroperitoneal hemorrhage or recurrence during follow-up. CONCLUSION: Treating renal AMLs with CA appears to be a safe and effective nephron-sparing approach and could...

  11. Giant renal oncocytoma.

    Science.gov (United States)

    Stojanović, Nebojsa; Ignjatovic, Ivan; Kostov, Milos; Mijović, Zaklina; Zivković, Sladjana; Kosević, Branko

    2013-01-01

    Renal onkocytoma is a distinctive benign tumor derived from epithelial cells of the distal renal tubules. These tumors are often clinically asymptomatic, diagnosed accidentally and difficult to distinguish from renal cell carcinoma. We presented a giant renal onkocytoma in a man aged 64, without any signs or symptoms of the urogenital system disorder. The preoperative diagnosis described the tumor mass of the right kidney, size 16 x 14 cm, and indicated a malignant tumor of kidney. The patient underwent radical nephrectomy. The tumor was encapsulated at the intersection with the characteristic central hyaline scar. Microscopically, it was built of uniform polygonal cells with abundant eosinophilic cytoplasm. Immunohystochemiclly, tumor cells were immunoreactive to CK AE1/AE3 and CD 117, but showed negative immunoreactivity to CK 7, RCC marker and Vimentin. Giant renal oncocytomas are rare tumors with benign clinical course. As a rule, they are discovered by accident. Clinical differentiation from malignant tumors of the kidney is not possible. They are treated surgically, mainly by radical nephrectomy. A definitive diagnosis is made only by histopathological examination of tumors using immunohistochemical marker panels.

  12. Giant renal oncocytoma

    Directory of Open Access Journals (Sweden)

    Stojanović Nebojša

    2013-01-01

    Full Text Available Background. Renal onkocytoma is a distinctive benign tumor derived from epithelial cells of the distal renal tubules. These tumors are often clinically asymptomatic, diagnosed accidentally and difficult to distinguish from renal cell carcinoma. Case report. We presented a giant renal onkocytoma in a man aged 64, without any signs or symptoms of the urogenital system disorder. The preoperative diagnosis described the tumor mass of the right kidney, size 16 x 14 cm, and indicated a malignant tumor of kidney. The patient underwent radical nephrectomy. The tumor was encapsulated at the intersection with the characteristic central hyaline scar. Microscopically, it was built of uniform polygonal cells with abundant eosinophilic cytoplasm. Immunohystochemiclly, tumor cells were immunoreactive to CK AE1/AE3 and CD 117, but showed negative immunoreactivity to CK 7, RCC marker and Vimentin. Conclusion. Giant renal oncocytomas are rare tumors with benign clinical course. As a rule, they are discovered by accident. Clinical differentiation from malignant tumors of the kidney is not possible. They are treated surgically, mainly by radical nephrectomy. A definitive diagnosis is made only by histopathological examination of tumors using immunohistochemical marker panels.

  13. [The focal renal lesions].

    Science.gov (United States)

    Tuma, Jan

    2013-06-05

    The focal renal lesions are altogether common. Most frequently are found Columna Bertini hypertrophies (so called pseudotumors) and simple renal cysts. The role of sonography in the practice is to distinguish pseudotumors from real renal tumors, and simple renal cysts from complex cysts. The differentiation of complex renal cysts is possible with the help of the CEUS (= contrast enhanced ultrasound) and other imaging modalities such as CT or MRI. In these cases, the CEUS imaging agent has clear advantages over CT and MRI, because it is composed of gas bubbles, which are only slightly smaller than red blood cells and remains exclusively intravascularly while the CT and MRI contrast agents diffuse into the interstitial space without any real perfusion. The real tumors can be differentiated from certain focal non-tumorous changes based on the ultrasound and clinic. The further differentiation of individual kidney tumors and metastases using ultrasound, MRI, CT and CEUS is only partly possible. In all uncertain or unclear cases, therefore, an open or ultrasound-guided biopsy is useful.

  14. Estudo comparativo dos métodos de ultra-sonografia, tomografia computadorizada e ressonância magnética no estadiamento e invasão das estruturas adjacentes por tumores renais A comparative study of ultrasonography, computed tomography and magnetic resonance imaging in the staging and invasion of adjacent structures by renal tumors

    Directory of Open Access Journals (Sweden)

    S.M. RIBEIRO

    2001-09-01

    para o diagnóstico como no estadiamento, devem ser considerados aspectos relativos à invasibilidade, riscos e preço na ponderação dos custos e benefícios dos diversos exames de diagnóstico por imagem.BACKGROUND: Ultrasonography (US, Computed Tomography (CT, and Magnetic Resonance imaging (MR were compared for the staging of renal tumors. The differences between these imaging techniques were also studied for their ability to detect adenopathies, vascular invasion, distant intra-abdominal metastases, and particularly adjacent organ invasion. METHODS: Thirty-one patients with solid or complex renal masses were prospectively studied using US, CT, and MR. Differences between the results obtained were studied using the COCHRAN G test and the Mc NEMAR test. The sensitivity and specificity of each diagnostic technique were compared against a "gold standard" of the surgical and histopathological findings. RESULTS: The following sensitivities were obtained: For the detection of adenopathy, US 63.6%, CT and MR 90.9%. For vascular invasion, US 42.8%, CT and MR 85.7%. For the adjacent organ invasion, US 28.5%, CT 85.7%, and MR 71.4%. Some of the criteria that suggest invasion of adjacent structures include: the envelopment of the adjacent structures by the tumor, tumor extension into the adjacent structures with an irregular appearance, and alterations in shape, size, and density of adjacent structures. Loss of fat planes between the tumor and adjacent structures is not a sign of tumor invasion. CONCLUSIONS: Significant differences were found in the detection capacity of US in relation to CT and MR, which were similar. All three techniques were highly sensitive and specific only in the detection of distant abdominal metastases. In addition to the accuracy of these diagnostic modalities for the detection and staging of tumors, invasiveness, risks and cost should be considered in relation to relative costs and benefits.

  15. Renal sympathetic denervation: MDCT evaluation of the renal arteries.

    LENUS (Irish Health Repository)

    Hutchinson, Barry D

    2013-08-01

    Percutaneous transluminal renal sympathetic denervation is a new treatment of refractory systemic hypertension. The purpose of this study was to assess the clinical utility of MDCT to evaluate the anatomic configuration of the renal arteries in the context of renal sympathetic denervation.

  16. Polyhydramnios and acute renal failure

    OpenAIRE

    Hamilton, D. V.; Kelly, Moira B.; Pryor, J. S.

    1980-01-01

    Acute renal failure secondary to ureteric obstruction is described in a primigravida with twin gestation and polyhydramnios. Relief of the obstruction occurred on drainage of the liquor and return to normal renal function following delivery.

  17. INTERMEDIATE SYNDROME: A TYPICAL PATTERN OF PRE-RENAL ACUTE RENAL FAILURE IN THE ELDERLY

    Directory of Open Access Journals (Sweden)

    Greloni G

    2004-01-01

    Full Text Available Acute renal failure is a frequent entity in the elderly. This is due on one hand to the structural and physiological changes of the aged kidney, and on the other hand to the exposure of this population to polypharmacy and their reduced capability to metabolize drugs. In the present report we present a case of a seventy year-old woman who developed acute renal failure secondary to severe dehydration with a clinical and laboratory pattern of intermediate syndrome: laboratory results compatible with parenchymal renal insufficiency (elevated urinary sodium, plasma urea and creatinine, but with a positive response to hydration. The main characteristics of the aged kidney that predispose to the development of an intermediate syndrome are: the vascular dysautonomy and reduced capability of sodium and water reabsorption. The intermediate syndrome is a typical pattern of pre-renal insufficiency in the elderly. RESUMEN: La insuficiencia renal aguda es frecuente en el anciano. Esto se debe por un lado a los cambios estructurales y funcionales propios del riñón senil, y por otro a la gran exposición que esta población tiene a la polifarmacia, y su reducida capacidad para metabolizar los medicamentos. En este reporte presentamos el caso de una mujer de 70 años que desarrolló una insuficiencia renal aguda secundaria a severa deshidratación, mostrando un patrón clínico y de laboratorio propio de un sindrome intermedio: laboratorios compatibles con una insuficiencia renal parenquimatosa (sodio urinario, uremia y creatininemia elevadas, pero con una respuesta favorable a la hidratación. Las principales características del riñón senil que predisponen al desarrollo del sindrome intermedio: son la disautonomía vascular y la reducida capacidad en la recuperación de sodio y agua El sindrome intermedio es un patrón típico de insuficiencia prerrenal en el anciano.

  18. [Renal transplantation in children].

    Science.gov (United States)

    Medeiros-Domingo, Mara; Romero-Navarro, Benjamín; Valverde-Rosas, Saúl; Delgadillo, Rodolfo; Varela-Fascinetto, Gustavo; Muñoz-Arizpe, Ricardo

    2005-01-01

    Despite being considered a high risk procedure, renal transplantation has been recognized for more than 20 years as the best therapeutic option for children with end-stage renal disease since it is superior than any available dialytic procedure in improving the neuropsychological development and the quality of life. Today pediatric patients have similar graft survival than adults, and 10 year-old children or less have better outcome than any other age group. These remarking results are due to the development of specialized pediatric transplant centers and research programs, improvement in the selection and preparation of donors and recipients, refinement of the surgical technique and the use of new immunossupressive drugs.

  19. Renal lithiasis and nutrition

    Science.gov (United States)

    Grases, Felix; Costa-Bauza, Antonia; Prieto, Rafel M

    2006-01-01

    Renal lithiasis is a multifactorial disease. An important number of etiologic factors can be adequately modified trough diet, since it must be considered that the urine composition is directly related to diet. In fact, the change of inappropriate habitual diet patterns should be the main measure to prevent kidney stones. In this paper, the relation between different dietary factors (liquid intake, pH, calcium, phosphate, oxalate, citrate, phytate, urate and vitamins) and each type of renal stone (calcium oxalate monohydrate papillary, calcium oxalate monohydrate unattached, calcium oxalate dihydrate, calcium oxalate dihydrate/hydroxyapatite, hydroxyapatite, struvite infectious, brushite, uric acid, calcium oxalate/uric acid and cystine) is discussed. PMID:16956397

  20. Renal lithiasis and nutrition

    Directory of Open Access Journals (Sweden)

    Prieto Rafel M

    2006-09-01

    Full Text Available Abstract Renal lithiasis is a multifactorial disease. An important number of etiologic factors can be adequately modified trough diet, since it must be considered that the urine composition is directly related to diet. In fact, the change of inappropriate habitual diet patterns should be the main measure to prevent kidney stones. In this paper, the relation between different dietary factors (liquid intake, pH, calcium, phosphate, oxalate, citrate, phytate, urate and vitamins and each type of renal stone (calcium oxalate monohydrate papillary, calcium oxalate monohydrate unattached, calcium oxalate dihydrate, calcium oxalate dihydrate/hydroxyapatite, hydroxyapatite, struvite infectious, brushite, uric acid, calcium oxalate/uric acid and cystine is discussed.

  1. Enfermedad renal poliquistica asociada a linfoma extranodal en un canino

    OpenAIRE

    Echeverry, Diego; Barbosa, Ximena; Buriticá, Edwin

    2006-01-01

    Objetivo: Presentar el caso de un paciente canino, con enfermedad renal poliquística, asociada a linfoma extranodal. Materiales y métodos: Se estudió el caso de un paciente canino de raza Siberian Husky de 7 años de edad, al que se le encontraron múltiples nódulos renales bilaterales, con diagnóstico histopatológico de linfoma extranodal. Resultados: Se expone el caso clínico de un paciente canino de raza Siberian Husky, que es presentado a consulta dermatológica por exhibir lesiones alopécic...

  2. Obesidad y enfermedad renal: consecuencias ocultas de la epidemia

    OpenAIRE

    Kovesdy, Csaba P.; Susan Furth; Carmine Zoccali; en nombre del Comité Directivo del Día Mundial del Riñón

    2017-01-01

    La obesidad se ha convertido en una epidemia mundial, y se ha proyectado que su prevalencia se incrementrá en un 40% en la próxima década. Esta creciente prevalencia supone implicaciones tanto para el riesgo de desarrollo de diabetes y enfermedades cardiovasculares como para el desarrollo de enfermedad renal crónica. Un elevado índice de masa corporal es uno de los factores de riesgo más importantes para el desarrollo de enfermedad renal crónica. En individuos afectados por la obesidad, tiene...

  3. Diabetes mellitus en el paciente con enfermedad renal avanzada

    OpenAIRE

    R. Verner Codoceo, Dr.

    2010-01-01

    La diabetes mellitus 2 (DM 2) y la enfermedad renal crónica (ERC) son considerados problemas de salud pública a nivel mundial. Los pronósticos de ambas enfermedades están estrechamente relacionados, por lo que las acciones terapéuticas son complementarias. Un buen control glicémico revierte las alteraciones renales en sus etapas iniciales disminuyendo el deterioro microangiopático ya su vez el intento de obtener un control óptimo de glicemias requiere conocer y tratar las alteraciones provoca...

  4. Renal replacement therapy in Europe

    DEFF Research Database (Denmark)

    Noordzij, Marlies; Kramer, Anneke; Abad Diez, José M

    2014-01-01

    BACKGROUND: This article provides a summary of the 2011 ERA-EDTA Registry Annual Report (available at www.era-edta-reg.org). METHODS: Data on renal replacement therapy (RRT) for end-stage renal disease (ESRD) from national and regional renal registries in 30 countries in Europe and bordering the ...

  5. Management of chronic renal failure.

    NARCIS (Netherlands)

    de Zeeuw, D.; Apperloo, AJ; de Jong, P.

    1992-01-01

    There is growing evidence that treatment of patients with renal function impairment will undergo a major shift within the next few years. Along with more or less successful attempts to alleviate the signs and symptoms of reduced renal function, new insights into renal pathophysiology as well as new

  6. Síndrome branquio-oto-renal: A propósito de una familia Branchio-oto-renal síndrome: Apropos of a family

    Directory of Open Access Journals (Sweden)

    Gretsy Arcas Ermeso

    2005-06-01

    Full Text Available El síndrome branquio-oto-renal es un trastorno que se transmite con un patrón autosómico dominante caracterizado por lesiones producidas por un trastorno embriológico branquial (fístulas o quistes branquiales, alteraciones del oído (hoyuelos o fositas preauriculares, apéndices, hipoplasias de pabellones auriculares y sordera, así como diversos tipos de displasia renal que pueden ir desde duplicaciones, desplazamientos e hipoplasias, hasta la agenesia renal y otras malformaciones mayores. Se presenta una familia integrada por un padre y dos hijos de ambos sexos y de diferentes matrimonios, en la cual se constató la presencia de este síndrome poco frecuenteThe branchio-oto-renal syndrome is a disorder that is transmitted with a dominant autosomic pattern characterized y lesions produced by a branchial embriological disorder (fistulas or branchial cysts, alterations of the ear (preauricular small pits or fossae, appendices, hypoplasias of auricular pavilions and deafness, as well as diverse types of renal dysplasia that may go from duplications and displacements to renal agenesia and other major malformations. A family composed of a father and two children of both sexes from different marriages, in which the presence of this uncommon syndrome was confirmed, is presented

  7. Advancements in renal protection

    NARCIS (Netherlands)

    Waanders, Femke

    2008-01-01

    Chronic kidney disease is a rising worldwide public health problem. The prevention of progressive renal function loss of both native and transplanted kidneys is therefore the main challenge in current clinical nephrology. Blockade of the renin-angiotensin aldosterone system (RAAS) with blood

  8. Chemokines in Renal Diseases

    Directory of Open Access Journals (Sweden)

    Stephan Segerer

    2005-01-01

    Full Text Available The chemokines, members of a large family of chemotactic cytokines, act as directional cues for sorting inflammatory cell subsets to sites of inflammation or lymphoid microenvironments. In addition to their effects on migration, chemokines can also activate effector function in leukocytes and are involved in cell proliferation and angiogenesis. Therefore, it is not surprising that chemokines play important roles in a wide range of human diseases, including genetic immunodeficiencies, infections, autoimmune diseases, and malignant tumors. In this report, we have reviewed recent developments (since mid 2003 in chemokines in renal diseases. In animal models, chemokines are produced at the site of injury, leading to inflammatory cell recruitment. The therapeutic impact of the blockade of CCR1, CCR2, CCR4, CCR5, or the corresponding ligands has been further studied in various renal disease models. Recent studies on the role of the chemokine receptors in human diseases have demonstrated the expression of CXCR1, CXCR3, CCR2, and CCR5 on different subsets of inflammatory cells. The number of CCR5- and CXCR3-positive interstitial infiltrating cells (mainly T cells correlates with renal function and proteinuria in glomerular diseases. Polymorphisms of chemokines and chemokine receptors are of impact on renal disease courses and allograft survival. Chemokine receptor blockade has approached clinical applications in nonrenal diseases and awaits the application in patients with kidney diseases.

  9. Renal scintigraphy in veterinary medicine.

    Science.gov (United States)

    Tyson, Reid; Daniel, Gregory B

    2014-01-01

    Renal scintigraphy is performed commonly in dogs and cats and has been used in a variety of other species. In a 2012 survey of the members of the Society of Veterinary Nuclear Medicine, 95% of the respondents indicated they perform renal scintigraphy in their practice. Renal scintigraphy is primarily used to assess renal function and to evaluate postrenal obstruction. This article reviews how renal scintigraphy is used in veterinary medicine and describes the methods of analysis. Species variation is also discussed. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Embolia pulmonar por polimetilmetacrilato

    OpenAIRE

    Héctor Gómez Santa María; Mauro García Aurelio; Yanina Castillo Costa; Víctor Mauro; Carlos Barrero

    2009-01-01

    Los primeros registros de embolia pulmonar por polimetilmetacrilato se publicaron recientemente (2003) y desde entonces se describieron no más de 15 casos. Se presenta el caso de un paciente joven a quien dos meses antes de la consulta se le había efectuado una vertebroplastia percutánea con polimetilmetacrilato. Por síntomas pleuríticos se le realizó una radiografía de tórax, que evidenció múltiples imágenes radioopacas en ambos campos pulmonares. La embolia pulmonar por polimetilmetacrilato...

  11. VENA RENAL IZQUIERDA RETRO-AÓRTICA. Retro-aortic left renal vein

    OpenAIRE

    Alejandro M Russo

    2016-01-01

    El conocimiento de la anatomía venosa del riñón y sus variaciones es esencial para realizar cualquier tipo de procedimiento en la región. Se reporta una variante del árbol venoso del riñón izquierdo, encontrado durante la disección cadavérica, la vena renal izquierda retro-aórtica. Se trató de un tronco único originado a nivel del hilio renal izquierdo que discurrió por detrás de la arteria aorta abdominal para finalizar en la vena cava inferior. La existencia de este vaso se asocia a la embr...

  12. ``Aggressive`` renal angiomyolipoma

    Energy Technology Data Exchange (ETDEWEB)

    Cittadini, G. Jr. [Univ. of Genoa (Italy). Dept. of Radiology; Pozzi Mucelli, F. [Univ. of Trieste (Italy). Dept. of Radiology; Danza, F.M. [Catholic Sacro Cuore Univ., Rome (Italy). Dept. of Radiology; Derchi, L.E. [Univ. of Genoa (Italy). Dept. of Radiology; Pozzi Mucelli, R.S. [Univ. of Trieste (Italy). Dept. of Radiology

    1996-11-01

    We describe the US and CT examinations of 4 patients with renal angiomyolipoma with an `aggressive` appearance, and review the literature. The imaging findings in 4 patients with benign renal angiomyolipomas associated with thrombosis of the renal vein and/or inferior vena cava are presented. CT demonstrated fat densities within both tumor and thrombus. In one patient, small lymph nodes with low density internal areas were detected in the para-aortic region. When considering our patients together with those reported in the literature, we found that most angiomyolipomas with venous invasion were large and centrally located within the kidney. Venous thrombosis was observed in 9 lesions of the right kidney, and in only 4 of the left one. One patient only had symptoms due to the thrombus; 10 had problems due to the tumor; and 3 were asymptomatic. Only 4 patients with pararenal enlarged lymph nodes have been reported on in the imaging literature. Fat-containing nodes were detected by CT in one case only; the others had enlarged nodes of soft-tissue density. In one patient the diagnosis of hamartomatous lymph node invasion was established by angiography. In patients with renal angiomyolipoma, demonstration of both fatty thrombus and the fatty infiltration of lymph nodes of the renal hilum cannot be regarded as an indication of malignancy, but only of local aggessive behavior. Conservative treatment seems possible. Detection of enlarged lymph nodes of soft tissue density may cause difficult diagnostic problems, with the diagnosis addressed only by the presence of associated lesions. (orig./MG).

  13. Embolia pulmonar por polimetilmetacrilato

    Directory of Open Access Journals (Sweden)

    Héctor Gómez Santa María

    2009-01-01

    Full Text Available Los primeros registros de embolia pulmonar por polimetilmetacrilato se publicaron recientemente (2003 y desde entonces se describieron no más de 15 casos. Se presenta el caso de un paciente joven a quien dos meses antes de la consulta se le había efectuado una vertebroplastia percutánea con polimetilmetacrilato. Por síntomas pleuríticos se le realizó una radiografía de tórax, que evidenció múltiples imágenes radioopacas en ambos campos pulmonares. La embolia pulmonar por polimetilmetacrilato es una complicación muy poco frecuente de ese procedimiento y un diagnóstico diferencial para tener en cuenta en pacientes con el antecedente y que consulten por dolor precordial o disnea.REV ARGENT CARDIOL 2009;77:129-130.

  14. Nefropatia induzida por contraste após tomografia computadorizada

    OpenAIRE

    Selistre, Luciano da Silva

    2009-01-01

    A nefropatia por contraste (NIC) é definida como uma piora na função renal que se segue à administração de contraste parenteral, tendo sido excluídas outras causas. A NIC manifesta-se, usualmente, como uma insuficiência renal aguda não oligúrica. Por definição, deve haver um aumento na creatinina basal de 25-50% ou um aumento superior a 0,5 mg/dl de 24 a 48 horas após o uso vascular de contraste. As medidas de prevenção são baseadas na correção dos fatores que levam ao desenvolvimento da NIC ...

  15. Transmissão da doença de Chagas por transplante renal: ocorrência da forma aguda da doença em dois receptores de um mesmo doador Transmission of Chagas' disease through transplantede kidney: occurrence of the acute form of the disease in two recipients from the same donor

    Directory of Open Access Journals (Sweden)

    A.S. Ferraz

    1993-10-01

    Full Text Available São apresentados dois casos de doença de Chagas aguda, adquiridos através de transplante de rins originários de um mesmo doador. O presente relato confirma a transmissão da doença de Chagas a partir do transplante renal e reforça a necessidade de exclusão de doadores renais infectados pelo Trypanosoma cruzi.Two cases of acute Chagas' disease acquired after renal transplantation are reported. The two patients received the kidney from the same donor. The present paper confirms this form of transmission of Chagas' disease and reinforces the need to exclude kidney donors with Trypanosoma cruzi infection.

  16. Estudio a largo plazo de la calidad de vida y remodelado estructural en pacientes en los que se realiza ablación mediante radiofrecuencia del flutter auricular típico

    OpenAIRE

    Cabanas Grandío, Pilar

    2013-01-01

    Introducción. La ablación del istmo cavotricuspídeo se ha establecido como tratamiento de elección para la prevención de recidivas en el flutter auricular (FlA) típico por su eficacia y seguridad. Sin embargo, se dispone de muy poca información sobre la calidad de vida a largo plazo de los pacientes sometidos a procedimiento de ablación del istmo cavotricuspídeo (ICT), así como del remodelado estructural y funcional de estos pacientes y la ocurrencia de fibrilación auricular (FA). Objetivo...

  17. Obesidad y enfermedad renal: consecuencias ocultas de la epidemia

    Directory of Open Access Journals (Sweden)

    Csaba P. Kovesdy

    2017-07-01

    Full Text Available La obesidad se ha convertido en una epidemia mundial, y se ha proyectado que su prevalencia se incrementrá en un 40% en la próxima década. Esta creciente prevalencia supone implicaciones tanto para el riesgo de desarrollo de diabetes y enfermedades cardiovasculares como para el desarrollo de enfermedad renal crónica. Un elevado índice de masa corporal es uno de los factores de riesgo más importantes para el desarrollo de enfermedad renal crónica. En individuos afectados por la obesidad, tiene lugar una hiperfiltración compensatoria necesaria para alcanzar la alta demanda metabólica secundaria al aumento del peso corporal. El incremeno de la presión intraglomerular puede generar daño renal y elevar el riesgo de desarrollar enfermedad renal crónica a largo plazo. La incidencia de glomerulopatía asociada a obesidad se ha incrementado 10 veces en los últimos años. Así mismo se ha demostrado que la obesidad es un factor de riesgo para el desarrollo de nefrolitiasis y un número de neoplasias, incluyendo cáncer renal. Este año, el Día Mundial del Riñón promueve la educación acerca de las consecuencias nocivas de la obesidad y su asociación con la enfermedad renal, abogando por un estilo de vida saludable y la implementación de políticas publicas de salud que promuevan medidas preventivas alcanzables.

  18. Screening renal stone formers for distal renal tubular acidosis

    DEFF Research Database (Denmark)

    Osther, P J; Hansen, A B; Røhl, H F

    1989-01-01

    A group of 110 consecutive renal stone formers were screened for distal renal tubular acidosis (RTA) using morning fasting urinary pH (mfUpH) levels followed by a short ammonium chloride loading test in patients with levels above 6.0. In 14 patients (12.7%) a renal acidification defect was noted......; 13 had incomplete and 1 had complete distal RTA. Distal RTA was found particularly in recurrent stone formers (17%), and especially in those with bilateral stone disease, where a distal renal tubular acidification defect was found in 50%. We have been unable to differentiate primary from secondary...... RTA in renal stone formers. Regardless of whether the acidification defect is primary or secondary to stone formation, however, all renal stone formers with distal RTA can expect to benefit from prophylactic alkaline therapy and it is recommended that the screening procedure, which is easy to use...

  19. Problemas renales de la cirrosis Renal problems of cirrhosis

    Directory of Open Access Journals (Sweden)

    Alvaro García

    1992-02-01

    Full Text Available Presentamos una revisión actualizada y condensada acerca de los problemas renales más relevantes que ocurren en la cirrosis tales como las alteraciones en el manejo del sodio y del agua, el tratamiento de la ascitis y el edema y el enfoque de la falla renal que ocurre en esta enfermedad, es decir síndrome hepato-renal y necrosis tubular aguda.

    We present a condensed and updated review on the most common renal problems occurring in cirrhosis such as the handling of sodium and water, the treatment of ascites and edema and the approach to the renal failure that frequently takes place in this disease, namely hepato-renal syndrome and acute tubular necrosis.

  20. Renal injury in sport.

    Science.gov (United States)

    Holmes, F Clarke; Hunt, Jeremy J; Sevier, Thomas L

    2003-04-01

    Hematuria is the most common presenting sign of renal injury. Its presence in athletes may indicate a benign entity such as exercise-induced hematuria or a more serious injury in the presence of trauma. Exercise-induced hematuria can originate in the kidney, bladder, urethra, or prostate. The type of activity, as well as activity duration and intensity, contributes to its development. A wide differential diagnosis must be considered if hematuria persists longer than 24 to 72 hours. Trauma to the kidney can occur from a direct blow or deceleration; contact and collision sports are most commonly involved. Fortunately, most sports-related renal trauma is mild, and can be managed expectantly. A sporting injury rarely results in nephrectomy. Determining return to play for the athlete with a single kidney remains a controversial issue that requires patient education and an individualized approach.

  1. Renal phosphate handling: Physiology

    Directory of Open Access Journals (Sweden)

    Narayan Prasad

    2013-01-01

    Full Text Available Phosphorus is a common anion. It plays an important role in energy generation. Renal phosphate handling is regulated by three organs parathyroid, kidney and bone through feedback loops. These counter regulatory loops also regulate intestinal absorption and thus maintain serum phosphorus concentration in physiologic range. The parathyroid hormone, vitamin D, Fibrogenic growth factor 23 (FGF23 and klotho coreceptor are the key regulators of phosphorus balance in body.

  2. Incidental Eosinophilic Chromophobe Renal Cell Carcinoma in Renal Allograft

    Directory of Open Access Journals (Sweden)

    Abdullah Alharbi

    2017-01-01

    Full Text Available The incidence of renal cell carcinoma (RCC in renal allograft in transplant recipients is 0.22–0.25%. De novo clear cell, papillary, and chromophobe RCCs and RCCs with sarcomatoid differentiation originating in renal allograft have been reported. Routine surveillance for graft tumours is not routinely practiced and these tumours are commonly asymptomatic and incidentally discovered. We describe a case of incidental, eosinophilic chromophobe RCC in a 31-year-old, long-term renal transplant male recipient, who presented with acute gastroenteritis 11 years after transplantation. The graft was nonfunctional at the time of presentation. Abdominal ultrasound and computed tomography scan demonstrated 1.8 cm well-defined, round enhancing lesion, confined to the renal allograft and suspicious for malignancy. Pathological examination of graft nephrectomy specimen showed gross, histopathological, and immunohistochemical features of eosinophilic chromophobe RCC. Fifty-five months after surgery, the patient was alive and free of malignancy. To the best of our knowledge, only five chromophobe RCCs originating in a renal allograft were previously described in English literature. We suggest that chromophobe RCC should be considered in the differential diagnosis of renal allograft mass, including eosinophilic tumours, and emphasise the importance of periodic screening of renal allograft in all renal transplant recipients.

  3. Incidental Eosinophilic Chromophobe Renal Cell Carcinoma in Renal Allograft.

    Science.gov (United States)

    Alharbi, Abdullah; Al Turki, Maram S; Aloudah, Noura; Alsaad, Khaled O

    2017-01-01

    The incidence of renal cell carcinoma (RCC) in renal allograft in transplant recipients is 0.22-0.25%. De novo clear cell, papillary, and chromophobe RCCs and RCCs with sarcomatoid differentiation originating in renal allograft have been reported. Routine surveillance for graft tumours is not routinely practiced and these tumours are commonly asymptomatic and incidentally discovered. We describe a case of incidental, eosinophilic chromophobe RCC in a 31-year-old, long-term renal transplant male recipient, who presented with acute gastroenteritis 11 years after transplantation. The graft was nonfunctional at the time of presentation. Abdominal ultrasound and computed tomography scan demonstrated 1.8 cm well-defined, round enhancing lesion, confined to the renal allograft and suspicious for malignancy. Pathological examination of graft nephrectomy specimen showed gross, histopathological, and immunohistochemical features of eosinophilic chromophobe RCC. Fifty-five months after surgery, the patient was alive and free of malignancy. To the best of our knowledge, only five chromophobe RCCs originating in a renal allograft were previously described in English literature. We suggest that chromophobe RCC should be considered in the differential diagnosis of renal allograft mass, including eosinophilic tumours, and emphasise the importance of periodic screening of renal allograft in all renal transplant recipients.

  4. Renal functional outcomes after surgery for renal cortical tumors

    Directory of Open Access Journals (Sweden)

    Danny Lascano

    2015-03-01

    Full Text Available Historically, radical nephrectomy represented the gold standard for the treatment of small (≤ 4cm as well as larger renal masses.  Recently, for small renal masses, the risk of ensuing chronic kidney disease and end stage renal disease has largely favored nephron-sparing surgical techniques, mainly partial nephrectomy. In this review, we surveyed the literature on renal functional outcomes after partial nephrectomy for renal tumors. The largest randomized control trial comparing radical and partial nephrectomy failed to show a survival benefit for partial nephrectomy. With regards to overall survival, surgically induced chronic kidney disease (GFR < 60 ml/min/ 1.73m2 caused by nephrectomy might not be as deleterious as medically induced chronic kidney disease. In evaluating patients who underwent donor nephrectomy, transplant literature further validates that surgically induced reductions in GFR may not affect patient survival, unlike medically induced GFR declines.  Yet, because patients who present with a renal mass tend to be elderly with multiple comorbidities, many develop a mixed picture of medically, and surgically-induced renal disease after extirpative renal surgery.  In this population, we believe that nephron sparing surgery optimizes oncological control while protecting renal function. 

  5. Efficacy of ultrasonography-guided renal biopsy for the evaluation of renal dysfunction following renal transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Jae; Choi, Chul Soon; Min, Seon Jeong; Lee, Gyung Kyu; Lee, Eil Seong; Kang, Ik Won; Bae, Sang Hoon [Hallym University College of Medicine, Chuncheon (Korea, Republic of)

    2003-12-15

    To evaluate the usefulness and complications of renal biopsy under ultrasonography-guidance in renal dysfunction after renal transplantation. Ultrasonography-guided renal biopsy was done in 47 patients with the transplanted kidney. The subjects consisted of 30 males and 17 females, age ranged from 16 to 66 years (average age=38 years). Biopsies were done once in 27 patients, twice in 17 patients, three times in 3 patients, a total of 70 biopsies. The success rate of renal biopsy for the accurate pathologic diagnosis and the incidence and types of complications following biopsy were evaluated. The success rate of renal biopsy for the accurate pathologic diagnosis was 96%(67/70). Pathologic diagnosis included 27 cases of acute rejection (39%), 8 cases of acute tubular necrosis (11%), 4 cases of acute rejection and acute tubular necrosis (6%), 4 cases of cyclosporin toxicity (6%), 4 cases of primary disease recurrence (6%), 4 cases of infection (6%) and others. Complications after renal biopsy included 15 cases of microscopic hematuria (21%), 1 case of gross hematuria with spontaneous cessation and 1 case of life threatening hemorrhage. Ultrasonography-guided renal biopsy is a safe and effective diagnostic method for the evaluation of renal dysfunction following renal transplantation.

  6. Radionuclide evaluation of renal function

    Energy Technology Data Exchange (ETDEWEB)

    Bueschen, A.J.; Witten, D.M.

    1979-06-01

    The renal scintillation camera study and the excretory urogram should be considered to be complementary studies. The renal scintillation camera study provides an accurate evaluation of changes in total, differential, and segmental renal function but affords only a gross assessment of anatomic changes. The excretory urogram provides superior information about renal anatomic changes but only inferior information about functional changes of the kidney. The advantages of a renal scintillation camera study with regard to the patient are that it is done in a state of normal hydration, it requires no bowel preparation, it is not associated with allergic reactions, it provides a low radiation exposure, and it is a noninvasive procedure for differential renal function which requires no ureteral catheters.

  7. Linfangiectasia renal: achado incidental em tomografia computadorizada multicorte e revisão da literatura

    Directory of Open Access Journals (Sweden)

    Rodrigo Abdalla de Vasconcelos

    2012-06-01

    Full Text Available Linfangiectasia renal é uma condição rara, caracterizada por coleções parapiélicas e perirrenais, que pode progredir de assintomática para insuficiência renal crônica. É apresentado um caso de achado incidental em tomografia computadorizada de linfangiectasia renal bilateral em paciente assintomático, com descrição dos principais achados à luz dos métodos de imagem e ampla revisão da literatura.

  8. Revisión actualizada sobre la insuficiencia renal aguda: estudio de un caso

    OpenAIRE

    Andreu Periz, Lola; Force Sanmartín, Enriqueta

    2003-01-01

    La insuficiencia renal aguda (IRA) o fracaso renal agudo es un síndrome clínico caracterizado por un deterioro brusco, frecuentemente reversible, de la función renal que provoca fallo de la homeostasia y se acompaña de retención de productos terminales del metabolismo nitrogenado, como la urea y la creatinina, junto con alteraciones del equilibrio hidroelectrolítico y ácidobase. Suele observarse oliguria (diuresis inferior a 400 ml/24 h), aunque algunas formas clínicas...

  9. Nefrectomía parcial laparoscópica en tumores renales

    OpenAIRE

    Castillo C,Octavio; Moreno J,Mauricio; Cortés O,Oscar; Pinto G,Iván; Arellano H,Leonardo; Russo N,Moisés

    2006-01-01

    Objetivo: Presentamos nuestra experiencia en nefrectomía parcial laparoscópica en el manejo de tumores renales localizados, destacando las indicaciones, la evolución de la técnica quirúrgica y los resultados obtenidos. Material y método: Se incluyen todos los pacientes a quienes se les practicó nefrectomía parcial laparoscópica por tumor renal sólido o quiste renal complejo entre julio de 1999 y julio del 2003. Resultados: Se intervinieron 56 pacientes: 15 mujeres y 41 hombres, con edad prome...

  10. Papel do p21 e do estresse oxidativo na resistência renal isquêmica

    OpenAIRE

    Flavia Kfouri

    2007-01-01

    A resistência tubular renal tem sido estudada a fim de se ampliar a compreensão da fisiopatologia da Insuficiência renal aguda (IRA). A isquemia renal induz à resistência a um subseqüente insulto isquêmico sendo que os mecanismos de resistência parecem depender de alterações celulares. O p21 é um inibidor do ciclo celular, o qual pode ser induzido por radicais livres de oxigênio e parece ter um efeito protetor na IRA isquêmica. O objetivo deste estudo é avaliar o papel do p21 e do estresse ox...

  11. ENFERMEDAD CARDIOVASCULAR (ECV) EN LA ENFERMEDAD RENAL CRÓNICA (ERC)

    OpenAIRE

    Orozco B., Rodrigo

    2015-01-01

    Desde la primera descripción de la asociación entre enfermedad renal crónica y enfermedad cardiaca, los estudios epidemiológicos han confirmado y extendido el conocimiento acerca de esta relación. El riesgo de enfermedad cardiovascular se incrementa al progresar la falla renal, probablemente por la suma de los factores de riesgo no tradicionales propios de la insuficiencia renal. No solamente es la patología cardiovascular más frecuente en esta población, sino que además es sub diagnosticada ...

  12. ENFERMEDAD RENAL POLIQUISTICA ASOCIADA A LINFOMA EXTRANODAL EN UN CANINO

    Directory of Open Access Journals (Sweden)

    Diego Echeverry B

    2006-12-01

    Full Text Available Objetivo: Presentar el caso de un paciente canino, con enfermedad renal poliquística, asociada alinfoma extranodal. Materiales y métodos: Se estudió el caso de un paciente canino de raza SiberianHusky de 7 años de edad, al que se le encontraron múltiples nódulos renales bilaterales, condiagnóstico histopatológico de linfoma extranodal. Resultados: Se expone el caso clínico de unpaciente canino de raza Siberian Husky, que es presentado a consulta dermatológica por exhibirlesiones alopécicas multifocales. Una vez realizado el examen físico sistemático se evidenció demanera incidental nefromegalia. Los exámenes paraclínicos e histopatológicos aplicadosdemostraron la presencia de enfermedad renal poliquística asociada a linfoma extranodal, comoconsecuencia se presento falla renal crónica. Conclusiones: El linfoma extranodal renal es unaentidad patológica de rara presentación, clínicamente cursa con signos muy similares a otrasalteraciones tumorales, su diagnóstico suele ser histopatológico.

  13. Asma inducido por ejercicio

    OpenAIRE

    Ramos Zabala, Mª Gracia

    1997-01-01

    Este trabajo consiste en una revisión de artículos y libros que tratan sobre el asma inducido por ejercicio. Principalmente me he basado en cinco artículos realizados en los últimos arios y en diferentes libros que me han servido de apoyo. Algunas consideraciones del asma inducido por el ejercicio son las siguientes: La probabilidad de presentar broncoespasmo, así como la intensidad del mismo, después de realizar ejercicio, se incrementa con la severidad del asma, aunque hay individuos en los...

  14. Razonamiento rebatible por casos

    OpenAIRE

    Bodanza, Gustavo A.

    1996-01-01

    Este trabajo constituye un estudio de las dificultades de la incorporación de información disyuntiva en un sistema conteniendo reglas rebatibles. Se presenta una ampliación del sistema MTDR a fin de aumentar la capacidad de éste, permitiendo el razonamiento por casos mediante argumentos. En un artículo anterior ([BS95]) se brindaba una aproximación al problema introduciendo una relación de inferencia rebatible que incluía la prueba por casos. Tal solución presenta limitaciones en determ...

  15. Plebiscito por la paz

    OpenAIRE

    Holmes Trujillo, Carlos; Cepeda, Iván

    2016-01-01

    Sin lugar a dudas, este tema podría permitir el cambio del rumbo de la historia en nuestro país, en tanto el próximo domingo 2 de octubre los colombianos podrán votar en un Plebiscito Nacional por el Sí o por el No a estos acuerdos de paz. En esta emisión, se darán los elementos para tomar la decisión no sólo de nuestro voto, sino nuestro compromiso como ciudadanos responsables.

  16. A case of renal oncocytoma

    OpenAIRE

    筧, 善行; 新井, 永植; 片村, 永樹

    1984-01-01

    We report a case of renal oncocytoma and review 158 cases in the literature. The patient was a 75-year-old woman whose chief complaint was epigastric discomfort without any urological symptoms. The right renal tumor was incidentally discovered by ultrasonography. Its angiographic patterns such as spoke-wheel appearance and homogeneous nephrogram were "characteristic" of renal oncocytoma. We diagnosed it as oncocytoma by microscopical and ultrastructural observation.

  17. Multiple oncocytomas and renal carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Velasquez, G.; Glass, T.A.; D' Souza, V.J.; Formanek, A.G.

    1984-01-01

    Renal oncocytoma, although rare, is being diagnosed more frequently, and criteria to differentiate it from other tumors have been described. Multiple oncocytomas have been reported, but an association between multiple oncocytomas and renal carcinoma in the same kidney has not been described. The authors report a case with two oncocytomas and a renal carcinoma in the right kidney as well as a right adrenal adenoma.

  18. Diabetes mellitus en el paciente con enfermedad renal avanzada

    Directory of Open Access Journals (Sweden)

    R. Verner Codoceo, Dr.

    2010-07-01

    Full Text Available La diabetes mellitus 2 (DM 2 y la enfermedad renal crónica (ERC son considerados problemas de salud pública a nivel mundial. Los pronósticos de ambas enfermedades están estrechamente relacionados, por lo que las acciones terapéuticas son complementarias. Un buen control glicémico revierte las alteraciones renales en sus etapas iniciales disminuyendo el deterioro microangiopático ya su vez el intento de obtener un control óptimo de glicemias requiere conocer y tratar las alteraciones provocadas por el ambiente urémico. Es muy importante considerar la existencia de cambios en la interpretación de los análisis de laboratorio, cambios en la farmacocinética y farmacodinamia de los medicamentos hipoglicemiantes e insulinas y finalmente la existencia de dificultades para realizar ejercicios y administrar una alimentación adecuada. Los esquemas de hipoglicemiantes utilizados, tanto medicamentos orales como insulinas, deben ser cuidadosamente personalizados. Se debe evitar la indicación de medicamentos de excreción renal exclusiva por el riesgo de hipoglicemias. Tanto las insulinas análogas como convencionales pueden ser administradas, con precaución en su dosificación y reconociendo la necesidad de un estricto automonitoreo de glicemia digital.

  19. Anatomy of renal arterial supply.

    Science.gov (United States)

    Khamanarong, K; Prachaney, P; Utraravichien, A; Tong-Un, T; Sripaoraya, K

    2004-05-01

    A thorough knowledge of the variations of the renal artery has grown in importance with the increasing numbers of renal transplants, vascular reconstructions, and various surgical and radiologic techniques. The literature indicates that multiple renal arteries are found in 9- 76% of cadavers. The purpose of this study is to establish the incidence and characteristics of variations of renal arteries in Thais. A total of 267 Thai cadavers were dissected in the anatomy laboratory. The anatomical findings included: a single hilar artery in 82% of cases; double renal arteries in 17% of cases (one hilar artery with an upper polar artery occurred in 7%; two hilar arteries in 7%, and one hilar artery combined with one lower polar artery in 3%); and triple renal arteries occurred in 1% (two hilar arteries with one upper polar artery in 0.4% and two hilar arteries with one lower polar artery in 0.6%). In preparation for interventions, such as living renal donation, vascular reconstruction, renovascular hypertension, or radical nephrectomy, the results indicate that preoperative renal imaging is necessary and that operative techniques with attention to multiple renal arteries should be considered. Copyright 2004 Wiley-Liss, Inc.

  20. Renal myxoma: a case report

    Directory of Open Access Journals (Sweden)

    Carlos Henrique C Souza

    2015-04-01

    Full Text Available Myxomas are rare tumors that can appear in many anatomical locations. There are only 14 cases of renal involvement documented in the literature. This article reports a case of renal myxoma in an elderly woman with recurrent cystitis. After five years of follow-up, the computed tomography (CT revealed a large solid tumor mass in the left kidney. Tumor resection was performed preserving the affected kidney with histopathological diagnosis of renal myxoma. The objective of this study is to report a rare case of renal myxoma, emphasizing the importance of the differential diagnosis from other benign and malignant mesenchymal tumors.

  1. Computed tomography of renal oncocytoma

    Energy Technology Data Exchange (ETDEWEB)

    Levine, E. (Univ. of Kansas, Kansas City); Huntrakoon, M.

    1983-10-01

    Renal oncocytoma is a relatively rare tumor that has an excellent prognosis and usually may be treated adequately by local resection. Preoperative differentiation from renal cell carcinoma, which requires radical nephrectomy, is thus of importance. The computed tomographic (CT) and pathologic features of three incidentally-detected renal oncocytomas were compared with those of six renal cell carcinomas of comparable size. Renal cell carcinoma appears on CT as a solid mass that generally has an indistinct interface with normal renal parenchyma, a lobulated contour, and a nonhomogeneous pattern of contrast enhancement. These features correlate with the pathologic findings of an irregular tumor margin and the frequent presence of tumor hemorrhage and necrosis. Oncocytoma, on the other hand, generally has a distinct margin, a smooth contour, and a homogeneous appearance on contrast-enhanced CT scans. These findings correlate with a smooth tumor margin and absence of tumor hemorrhage and necrosis on pathologic examination. These features are not pathognomonic of oncocytoma, as angiographic evidence suggests that renal cell carcinoma may show both distinct margination and a homogeneous blush in 6% of cases. However, their demonstration by CT should alert radiologists and surgeons to the possibility that a renal mass may be an oncocytoma. Such a presumptive diagnosis then can lead to a surgical approach that allows for renal-conserving surgery.

  2. Renal replacement therapy in ICU

    Directory of Open Access Journals (Sweden)

    C Deepa

    2012-01-01

    Full Text Available Diagnosing and managing critically ill patients with renal dysfunction is a part of the daily routine of an intensivist. Acute kidney insufficiency substantially contributes to the morbidity and mortality of critically ill patients. Renal replacement therapy (RRT not only does play a significant role in the treatment of patients with renal failure, acute as well as chronic, but also has spread its domains to the treatment of many other disease conditions such as myaesthenia gravis, septic shock and acute on chronic liver failure. This article briefly outlines the role of renal replacement therapy in ICU.

  3. Image-Guided Renal Intervention.

    Science.gov (United States)

    Frey, Gregory T; Sella, David M; Atwell, Thomas D

    2015-09-01

    The role of interventional radiology in the management of renal malignancy has expanded in the past 2 decades, largely because of the efficacy of image-guided ablation in treating renal cell carcinoma (RCC). Clinical guidelines now incorporate ablation into standardized RCC management algorithms. Importantly, both radiofrequency ablation and cryoablation have shown long-term durability in the definitive treatment of RCC, and early outcomes following microwave ablation are equally promising. While selective renal artery embolization has a role in the palliation of select patients with RCC, it can also be used to minimize complications in the ablation of larger renal masses. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Sporotrichosis in Renal Transplant Patients

    Directory of Open Access Journals (Sweden)

    Paulo Gewehr

    2013-01-01

    Full Text Available The current report describes two renal transplant recipients who presented with sporotrichosis. In addition, the authors review the general aspects of sporotrichosis in renal transplant recipients reported in the literature. Sporotrichosis is a rare fungal infection in transplant patients and has been reported primarily in renal transplant recipients not treated with antifungal prophylaxis. Extracutaneous forms of sporotrichosis without skin manifestations and no previous history of traumatic injuries have been described in such patients and are difficult to diagnose. Renal transplant recipients with sporotrichosis described in the present report were successfully treated with antifungal therapy including amphotericin B deoxycholate, lipid amphotericin B formulations, fluconazole and itraconazole.

  5. Urolitíase no alotransplante renal

    Directory of Open Access Journals (Sweden)

    Cologna Adauto José

    2003-01-01

    Full Text Available OBJETIVO: A litíase urinária é uma complicação incomum no alotransplante renal, a incidência varia de 0,02 a 3,4%. A maioria dos cálculos forma-se após o transplante, porém alguns podem ser transferidos junto com o enxerto para o hospedeiro. O tratamento desta complicação está baseado em alguns casos descritos na literatura. O objetivo deste trabalho é o de relatar a incidência da litíase renal no paciente com transplante renal, assim como a conduta adotada no HCFMRPUSP. MÉTODOS: Foram analisados 953 pacientes submetidos a transplante renal no HCFMRPUSP, de fevereiro 1968 a maio de 2003. A idade média foi de 47,2 anos (35 a 63 anos. Em 09 pacientes, o rim foi proveniente de doador cadáver e apenas 01 doador vivo. RESULTADOS:Foram diagnosticados 10 casos de litíase (1,05%. Em 02 pacientes (20% o cálculo foi diagnosticado no intraoperatório, em 01 (10% no peri-operatório (5º. dia, os 07 restantes (70% no pós-operatório tardio. Em 04 pacientes (57% não havia sintomatologia específica, 02 (29% apresentaram ITU, em 03 (43% ocorreu elevação da creatinina sérica. De 8 pacientes com litíase no pós-operatorio, em 06 os cálculos estavam localizados no rim e 02 no ureter. Dos pacientes com cálculos renais, 02 foram observados, 02 submetidos a LECO, 01 a nefrolitripsia percutânea, 01 à pielolitotomia. Em 01 paciente com cálculo ureteral foi realizada pielovesicostomia (cálculo + estenose, no outro paciente foi feita a ureterorrenoscopia retrógrada. CONCLUSÃO: A urolitíase é complicação rara no transplante renal, a conduta terapêutica no pós-operatório tardio é semelhante à da população geral.

  6. Renal cirsoid arteriovenous malformation masquerading as neoplasia.

    Science.gov (United States)

    Silverthorn, K; George, D

    1988-12-01

    A woman with renal colic and microscopic hematuria had filling defects in the left renal collecting system detected on excretory urography. A nephrectomy, performed because of suspected malignancy, might have been averted by renal angiography.

  7. Renal dysplasia in a Limousin calf Displasia renal em um bezerro Limousin

    Directory of Open Access Journals (Sweden)

    M.B. Castro

    2007-04-01

    Full Text Available Descreve-se um caso de displasia renal em um bezerro Limousin, macho, de quatro meses. O animal apresentava perda de peso, baixa taxa de crescimento, anorexia, apatia, diarréia escura fétida e uremia, sem melhora apesar de tratamento. O bezerro foi sacrificado para interromper o sofrimento adicional e submetido à necropsia. Ao exame foi observado que os rins estavam pequenos, firmes, pálidos e com superfície rugosa. A cápsula estava aderida à uma superfície subcapsular irregular. O córtex tinha aparência difusamente pálida e fibrosa e apresentava múltiplos focos brancos de fibrose. A junção córtico-medular estava indistinta. O exame histologico dos rins revelou múltiplos glomérulos imaturos com núcleo periférico, capilares inaparentes e padrão arbóreo. O córtex renal apresentou túbulos primitivos com epitélio cubóide ou cilíndrico envolvido por mesênquima corado somente pelo alcian blue e não pelo tricrômico de Masson. Foi também observada leve fibrose intersticial na medula renal. Os rins mostravam estruturas em estágio inapropriado de desenvolvimento ou anômalas.

  8. Renal vein oxygen saturation in renal artery stenosis

    DEFF Research Database (Denmark)

    Nielsen, K; Rehling, M; Henriksen, Jens Henrik Sahl

    1992-01-01

    Renal vein oxygen-saturation was measured in 56 patients with arterial hypertension and unilateral stenosis or occlusion of the renal artery. Oxygen-saturation in blood from the ischaemic kidney (84.4%, range 73-93%) was significantly higher than that from the 'normal' contralateral kidney (81...

  9. The evaluation of renal parenchymal scarring using static renal ...

    African Journals Online (AJOL)

    Objective: To analyze whether operative techniques and other variables related to patient and renal stone characteristics affect potential renal parenchymal damage. Materials and Methods: The study population comprised 64 patients who underwent percutaneous nephrolithotomy operations (PCNL). Data of the operated ...

  10. Renal hemodynamic effect of tacrolimus in renal transplanted children.

    Science.gov (United States)

    Dello Strologo, L; Pontesilli, C; Montini, G; Ginevri, F; Ardissino, G; Campagnano, P; Pastore, A; Federici, G; Rizzoni, G

    2001-10-01

    Like cyclosporine (CsA), tacrolimus acts through the inhibition of renal phosphatase calcineurin. CsA induces reversible vasoconstriction, causing a transient reduction of renal plasma flow in patients with renal transplantation. The aim of this study was to determine the effect of tacrolimus on renal plasma flow in renal transplanted children. Eight children were studied with a median age of 10.6 years, a mean glomerular filtration rate (inulin clearance) of 55 ml/min per 1.73 m2 (range 29-95), and a mean follow-up after transplantation of 5.6 months. Effective renal plasma flow (ERPF) was studied in each patient for 12 h after tacrolimus administration. Clearances were obtained every 2 h for 12 h after drug administration. Tacrolimus pharmacokinetics was also studied. Average ERPF at the start of the test was 289 ml/min per 1.73 m2 (range 177-404, SD +/- 106). Variation in each of the 2-h periods was not significant, although a mild reduction of plasma flow was observed in three of the eight children. No correlation was found between tacrolimus AUC, peak, or trough levels and renal blood flow variations. Despite the relatively small number of patients studied, these data suggest that, in vivo, a therapeutic oral dose of tacrolimus is not necessarily followed by a significant reduction of ERPF in renal transplanted children.

  11. Renal epithelioid angiomyolipoma presenting clinically as renal cell ...

    African Journals Online (AJOL)

    We describe a 22-year old female who presented with a 5-year history of a palpable, painless mass in the right flank. Computerized tomography demonstrated a solid renal mass measuring 18 cm × 13 cm with peripheral calcification, areas of vascularity and necrosis. The appearance suggested renal cell carcinoma or ...

  12. TEST DE FUROSEMIDA : SU PATRÓN EN LA INSUFICIENCIA RENAL CRÓNICA NO SEVERA

    OpenAIRE

    Musso, Carlos G; Soledad Crucelegui; Juliana Reynaldi; Bernardo Martinez; Carolina Aparicio; Manuel Vilas; Luis Algranati

    2008-01-01

    El test de furosemida consiste en una prueba de fisiología renal que se utiliza para evaluar la capacidad de los túbulos colectores para secretar potasio. Dicho estímulo está mediado por acción de la hormona aldosterona, cuyos niveles séricos se elevan tras el suministro de furosemida. Si bien el patrón de respuesta de este test ha sido descrito en niños y jóvenes sanos, no se lo ha hecho aun en pacientes portadores de insuficiencia renal crónica. Por este motivo se decidió realizar el siguie...

  13. Renal posttransplant's vascular complications

    Directory of Open Access Journals (Sweden)

    Bašić Dragoslav

    2003-01-01

    Full Text Available INTRODUCTION Despite high graft and recipient survival figures worldwide today, a variety of technical complications can threaten the transplant in the postoperative period. Vascular complications are commonly related to technical problems in establishing vascular continuity or to damage that occurs during donor nephrectomy or preservation [13]. AIM The aim of the presenting study is to evaluate counts and rates of vascular complications after renal transplantation and to compare the outcome by donor type. MATERIAL AND METHODS A total of 463 kidneys (319 from living related donor LD and 144 from cadaveric donor - CD were transplanted during the period between June 1975 and December 1998 at the Urology & Nephrology Institute of Clinical Centre of Serbia in Belgrade. Average recipients' age was 33.7 years (15-54 in LD group and 39.8 (19-62 in CD group. Retrospectively, we analyzed medical records of all recipients. Statistical analysis is estimated using Hi-squared test and Fischer's test of exact probability. RESULTS Major vascular complications including vascular anastomosis thrombosis, internal iliac artery stenosis, internal iliac artery rupture obliterant vasculitis and external iliac vein rupture were analyzed. In 25 recipients (5.4% some of major vascular complications were detected. Among these cases, 22 of them were from CD group vs. three from LD group. Relative rate of these complications was higher in CD group vs. LD group (p<0.0001. Among these complications dominant one was vascular anastomosis thrombosis which occurred in 18 recipients (17 from CD vs. one from LD. Of these recipients 16 from CD lost the graft, while the rest of two (one from each group had lethal outcome. DISCUSSION Thrombosis of renal allograft vascular anastomosis site is the most severe complication following renal transplantation. In the literature, renal allograft thrombosis is reported with different incidence rates, from 0.5-4% [14, 15, 16]. Data from the

  14. [Renal abnormalities in ankylosing spondylitis].

    Science.gov (United States)

    Samia, Barbouch; Hazgui, Faiçal; Abdelghani, Khaoula Ben; Hamida, Fethi Ben; Goucha, Rym; Hedri, Hafedh; Taarit, Chokri Ben; Maiz, Hedi Ben; Kheder, Adel

    2012-07-01

    We will study the epidemiologic, clinical, biological, therapeutic, prognostic characteristics and predictive factors of development of nephropathy in ankylosing spondylitis patients. We retrospectively reviewed the medical record of 32 cases with renal involvement among 212 cases of ankylosing spondylitis followed in our service during the period spread out between 1978 and 2006. The renal involvement occurred in all patients a mean of 12 years after the clinical onset of the rheumatic disease. Thirty-two patients presented one or more signs of renal involvement: microscopic hematuria in 22 patients, proteinuria in 23 patients, nephrotic syndrome in 11 patients and decreased renal function in 24 patients (75%). Secondary renal amyloidosis (13 patients), which corresponds to a prevalence of 6,1% and tubulointerstitial nephropathy (7 patients) were the most common cause of renal involvement in ankylosing spondylitis followed by IgA nephropathy (4 patients). Seventeen patients evolved to the end stage renal disease after an average time of 29.8 ± 46 months. The average follow-up of the patients was 4,4 years. By comparing the 32 patients presenting a SPA and renal disease to 88 with SPA and without nephropathy, we detected the predictive factors of occurred of nephropathy: tobacco, intense inflammatory syndrome, sacroileite stage 3 or 4 and presence of column bamboo. The finding of 75% of the patients presented a renal failure at the time of the diagnosis of renal involvement suggests that evidence of renal abnormality involvement should be actively sought in this disease. Copyright © 2011 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved.

  15. Utility of the RENAL index -Radius; Exophytic/endophytic; Nearness to sinus; Anterior/posterior; Location relative to polar lines- in the management of renal masses.

    Science.gov (United States)

    Konstantinidis, C; Trilla, E; Lorente, D; Morote, J

    2016-12-01

    The growing incidence of renal masses and the wide range of available treatments require predictive tools that support the decision making process. The RENAL index -Radius; Exophytic/endophytic; Nearness to sinus; Anterior/posterior; Location relative to polar lines- helps standardise the anatomy of a renal mass by differentiating 3 groups of complexity. Since the introduction of the index, there have been a growing number of studies, some of which have been conflicting, that have evaluated the clinical utility of its implementation. To analyse the scientific evidence on the relationship between the RENAL index and the main strategies for managing renal masses. A search was conducted in the Medline database, which found 576 references on the RENAL index. In keeping with the PRISM Declaration, we selected 100 abstracts and ultimately reviewed 96 articles. The RENAL index has a high degree of interobserver correlation and has been validated as a predictive nomogram of histological results. In active surveillance, the index has been related to the tumour growth rate and probability of nephrectomy. In ablative therapy, the index has been associated with therapeutic efficacy, complications and tumour recurrence. In partial nephrectomy, the index has been related to the rate of complications, conversion to radical surgery, ischaemia time, function preservation and tumour recurrence, a finding also observed in radical nephrectomy. The RENAL index is an objective, reproducible and useful system as a predictive tool of highly relevant clinical parameters such as the rate of complications, ischaemia time, renal function and oncological results in the various currently accepted treatments for the management of renal masses. Copyright © 2016 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Displasia renal multiquística segmentaria: primeros casos registrados en Cuba Segmental multicystic renal dysplasia: First cases registered in Cuba

    Directory of Open Access Journals (Sweden)

    Sandalio Durán Álvarez

    2009-03-01

    Full Text Available La displasia renal multiquística segmentaria es un subtipo raro de displasia renal que puede confundirse prenatalmente con una displasia multiquística total, un doble sistema obstruido o una hidronefrosis por estenosis de la unión pieloureteral. Se presentan los casos de dos niñas con esta variedad de displasia. En una de ellas la imagen del ultrasonido maternofetal, e incluso el primer ultrasonido renal, se confundió con una hidronefrosis. En la otra, el ultrasonido de las 22 semanas de gestación detectó quistes renales y el primer ultrasonido renal antes de egresar de la maternidad hizo sospechar esta variedad de displasia. Se propone el control imagenológico expectante, sin realizar exéresis de la masa quística, pero atentos a las posibles complicaciones y con el consentimiento informado de los padres.Segmental multicystic renal dysplasia is a rare subtype of renal dysplasia that may be mistake with a total multicystic dysplasia, an obstructed double system or a hydronephrosis by stenosis of pyeloureteral junction. Authors present cases of two girls presenting with this variety of dysplasia. In one of them maternal-fetal US image, and even the first renal US, was confounded with a hydronephrosis. In the other case, US of 22 weeks of pregnancy sowed renal cysts, and in the first renal US before admission in unit, raise suspicion of this variety of dysplasia. We propose the expectant imaging control, without performing exeresis of cystic mass, but we must to be attentive to possible complications, and with informed consent of parents.

  17. Retro-Aortic Inverted Left Renal Vein: A Rare Anomaly Found in a Renal Donor

    OpenAIRE

    Sabouri, Sofia; Hosseini, Ashrafsadat; Shivaei, Seyedeh Shirin

    2015-01-01

    Awareness of the renal vascular anatomy including variants of the renal vein is important for abdominal and renal surgeries, such as renal transplantation. The complex embryological development of the renal vein results in the following variations: additional renal veins on the left side, circum-aortic renal collar and retro-aortic renal veins. In this report, we present a case of a 35-year-old renal donor who had a rare renal vein anomaly that had been shown by computed tomography (CT) angio...

  18. Insuficiencia renal aguda obstructiva: Estudio de 42 pacientes

    Directory of Open Access Journals (Sweden)

    Isabel Caravia Pubillones

    1997-04-01

    Full Text Available Se revisaron las historias clínicas de 42 pacientes ingresados en el Servicio de Cuidados Intensivos del Instituto de Nefrología con el diagnóstico de insuficiencia renal aguda obstructiva (IRAO, con 1 ó 2 riñones funcionantes. Los pacientes estudiados estaban entre la 5ta y la 7ma década de la vida, con una mayor incidencia en el sexo masculino. La causa más frecuente de IRAO fue la litiasis renal (47,62 %, seguida por las enfermedades tumorales que infiltraban los uréteres (28,57 %. Se empleó tratamiento médico en 9 pacientes y el resto (33 fueron sometidos a tratamiento quirúrgico. Las principales complicaciones fueron sépticas con un franco predominio de las infecciones del tractus urinario (38,5 %. Hubo 3 fallecidos, 2 de ellos por complicaciones cardiovasculares. Del total de insuficiencias renales agudas que se atendieron en nuestro Centro, el 10,6 % correspondió a IRAO. La efectividad del tratamiento quirúrgico empleado fue del 94,4 % de curación en los pacientes atendidosMedical records of 42 patients admitted to the Intensive Care Unit of the Institute of Nephrology diagnosed as having acute obstructive renal failure with 1 or 2 kidneys functioning, were revised. Patients studied ware at the 5th and 7th decade of life with a greater incidence in males. The most frequent cause of acute obstructive renal failure was renal lithiasis (47.62 %, followed by tumor diseases which were infiltrating the ureters (28.57 %. Medical treatment was employed in 9 patients and the remaining (33 were submitted to surgical treatment. The main complications were septic with predominance of urinary tract infections (38.5 %. Three patients died, 2 of them as a result of cardiovascular complications. Of the total number of cases presenting with acute renal failure and treated in our center, 10.6 % had an acute obstructive renal failure. The effectiveness of the surgical treatment performed was 94.4 % of healing in patients treated for this

  19. Fast renal decline to end-stage renal disease

    DEFF Research Database (Denmark)

    Krolewski, Andrzej S.; Skupien, Jan; Rossing, Peter

    2017-01-01

    A new model of diabetic nephropathy in type 1 diabetes emerged from our studies of Joslin Clinic patients. The dominant feature is progressive renal decline, not albuminuria. This decline is a unidirectional process commencing while patients have normal renal function and, in the majority......, progressing steadily (linearly) to end-stage renal disease (ESRD). While an individual's rate of renal decline is constant, the estimated glomerular filtration rate (eGFR) slope varies widely among individuals from –72 to –3.0 ml/min/year. Kidney Disease: Improving Global Outcomes guidelines define rapid......, that very fast and fast decline from normal eGFR to ESRD within 2 to 10 years constitutes 50% of the Joslin cohort. In this review we present data about frequency of fast decliners in both diabetes types, survey some mechanisms underlying fast renal decline, discuss methods of identifying patients at risk...

  20. Renal cystic diseases and renal neoplasms: a mini-review.

    Science.gov (United States)

    Bonsib, Stephen M

    2009-12-01

    The past two decades have witnessed recognition of several new types of renal cell carcinoma, each with distinct cytogenetic abnormalities. Included are several genetic and acquired cystic kidney diseases associated with development of renal cell carcinoma, the topic of this review. The risk in patients with autosomal dominant polycystic kidney disease is not accurately known but may be slightly increased. The risk for patients with von Hippel-Lindau disease is substantial, and death from renal cancer is common. For patients with tuberous sclerosis complex, the challenge is recognition of the occasional malignancy arising in a field of many benign tumors. Patients with end-stage kidney disease and acquired cystic kidney disease may develop a variety of renal cell carcinoma types. Progress in understanding the molecular basis of renal cyst formation and neoplastic disease has fostered development of targeted therapies that now hold promise for a group of neoplasms whose cure was traditionally dependent on surgical approaches.

  1. Citrato y litiasis renal

    Directory of Open Access Journals (Sweden)

    Elisa E. Del Valle

    2013-08-01

    Full Text Available El citrato es un potente inhibidor de la cristalización de sales de calcio. La hipocitraturia es una alteración bioquímica frecuente en la formación de cálculos de calcio en adultos y especialmente en niños. El pH ácido (sistémico, tubular e intracelular es el principal determinante de la excreción de citrato en la orina. Si bien la mayoría de los pacientes con litiasis renal presentan hipocitraturia idiopática, hay un número de causas para esta anormalidad que incluyen acidosis tubular renal distal, hipokalemia, dietas ricas en proteínas de origen animal y/o dietas bajas en álcalis y ciertas drogas, como la acetazolamida, topiramato, IECA y tiazidas. Las modificaciones dietéticas que benefician a estos pacientes incluyen: alta ingesta de líquidos y frutas, especialmente cítricos, restricción de sodio y proteínas, con consumo normal de calcio. El tratamiento con citrato de potasio es efectivo en pacientes con hipocitraturia primaria o secundaria y en aquellos desordenes en la acidificación, que provocan un pH urinario persistentemente ácido. Los efectos adversos son bajos y están referidos al tracto gastrointestinal. Si bien hay diferentes preparaciones de citrato (citrato de potasio, citrato de sodio, citrato de potasio-magnesio en nuestro país solo está disponible el citrato de potasio en polvo que es muy útil para corregir la hipocitraturia y el pH urinario bajo, y reducir marcadamente la recurrencia de la litiasis renal.

  2. Cell therapy in renal and cardiovascular disease Terapia celular en enfermedades renales y cardiovasculares

    Directory of Open Access Journals (Sweden)

    Juan Manuel Senior Sánchez

    2006-01-01

    Full Text Available Although there have been important advances in the field of molecular biology, the mechanisms responsible for nephrogenesis and the factors that modulate the process of development, proliferation, growth, and maturation during fetal and adult life have not been thoroughly explained. Animals, including mammals, share the intrinsic ability to regenerate tissues and organs as an important biological defense mechanism. In the case of the kidney, after tissue damage secondary to injury, anatomical and functional recovery of integrity is achieved, accompanied by the activation of a complex, poorly understood process, leading to the replacement of damaged tubular cells by functional ones that reorganize tubular architecture. This regeneration and repair process is produced by somatic, exogenous, adult stem cells, and probably by intrinsic renal stem cells, that are responsible for maintaining renal homeostasis Aunque se han logrado grandes avances en el campo de la biología molecular, todavía no se han esclarecido completamente los mecanismos responsables de la organogénesis y los factores que modulan el proceso de desarrollo, proliferación, crecimiento y maduración celulares durante la vida fetal y adulta. Los animales comparten la capacidad de regenerar tejidos y órganos, como un mecanismo biológico importante de defensa. En el caso del riñón, luego del daño tisular secundario a una noxa, se produce recuperación anatómica y funcional de la integridad, acompañada por la activación de un proceso sofisticado, mal comprendido, que lleva al reemplazo de las células tubulares dañadas por otras funcionalmente normales que reorganizan la arquitectura tubular. Este fenómeno de recambio se produce gracias a la presencia de células madre adultas somáticas exógenas, responsables del proceso de mantenimiento de la homeostasis renal, y posiblemente por células renales intrínsecas.

  3. Caso clínico-anatomopatológico: Las diversas presentaciones de la nefropatía por IgA

    Directory of Open Access Journals (Sweden)

    B. Rodrigo Orozco, Dr.

    2010-07-01

    Full Text Available Se trata de una paciente de 58 años, sexo femenino, que se presenta con hematuria, proteinuria severa y función renal normal. Pocas semanas después, ella desarrolla una trombosis de vena renal, embolia pulmonar secundaria y un episodio de insuficiencia renal aguda. Este caso clínico ilustra las distintas presentaciones clínicas de una nefropatía por IgA grave, incluyendo hematuria, síndrome nefrótico y trombosis de vena renal. Además muestra otras complicaciones serias, como embolia pulmonar y falla renal aguda. La paciente fue sometida a 2 biopsias renales, que permitieron una correlación adecuada entre las manifestaciones clínicas y la patología renal.

  4. Hemodinâmica glomerular renal no roedor Calomys callosus

    Directory of Open Access Journals (Sweden)

    Mirian A. Boim

    1989-03-01

    Full Text Available A função renal do roedor Calomys callosus, envolvido no ciclo de transmissão de diversos agentes patogênicos para o homem foi avaliada no animal intacto, através da técnica de depuração e micropunção renal. Os resultados mostraram que este roedor apresenta níveis pressóricos, hematócrito e proteinas plasmáticas semelhantes aos dos ratos submetidos ao mesmo procedimento experimental. Os pesos corporal e renal, bem como a filtração glomerular global e por nefro assemelham-se aos do camundongo. Surpreendentemente estes roedores apresentaram significante número de glomérulos superficiais por rim, permitindo a avaliação da hemodinàmica glomerular. Apesar da pressão arterial semelhante à dos ratos Munich-Wistar (MW, a pressão hidráulica intraglomerular no Calomys callosus foi inferior. Esta redução foi conseqüente à menor resistência pós-glomerular quando comparada à dos ratos MW. O fluxo plasmático glomerular atingiu valor bastante elevado em relação à filtração glomerular por nefro, fato que não só compensaria a reduzida pressão intraglomerular, como também seria suficiente para elevar a filtração (por g/rim a níveis superiores neste roedor, pois o coeficiente de ultrafiltração glomerular (Kj foi semelhante ao do rato MW. O presente trabalho sugere que apesar das dificuldades técnicas que este animal impõe devido ao seu reduzido tamanho, o estudo da função renal global bem como da hemodinàmica glomerular é factível, podendo portanto ser utilizado como modelo para estudo da função renal em doenças tropicais.Renal function was characterized in Calomys callosus, a rodent which can participate in the transmission of several human diseases. The results showed that the pressures levels, hematocrit and plasmatic proteins were similar to rats submitted to the same experimental maneuvers. The corporal and renal weights, whole and single nephron glomerular filtration rates were similar to the mouse

  5. Renal infarct following varicella infection

    Directory of Open Access Journals (Sweden)

    D Arora

    2016-01-01

    Full Text Available Renal infarction usually occurs against a background of heart disease or a thromboembolic tendency and rarely is associated with infections. Here we present a case of a young boy who reported with painless gross hematuria following primary Varicella infection and was found to have an isolated renal infarct.

  6. Leiomyosarcoma of the renal vein

    Directory of Open Access Journals (Sweden)

    Lemos Gustavo C.

    2003-01-01

    Full Text Available Leiomyosarcoma of the renal vein is a rare tumor of complex diagnosis. We presented a case of renal vein leiomyosarcoma detected in a routine study. The primary treatment was complete surgical removal of the mass. In cases where surgical removal is not possible the prognosis is poor, with high rates of local recurrence and distant spread.

  7. Stages of Renal Cell Cancer

    Science.gov (United States)

    ... through the urethra and leaves the body. Enlarge Anatomy of the male urinary system (left panel) and female urinary system (right panel) showing the kidneys, ureters, bladder, and urethra. Urine is made in the renal tubules and collects in the renal pelvis of ...

  8. Renal replacement therapy in Europe

    DEFF Research Database (Denmark)

    Pippias, Maria; Stel, Vianda S; Abad Diez, José Maria

    2015-01-01

    BACKGROUND: This article summarizes the 2012 European Renal Association-European Dialysis and Transplant Association Registry Annual Report (available at www.era-edta-reg.org) with a specific focus on older patients (defined as ≥65 years). METHODS: Data provided by 45 national or regional renal r...

  9. [Estimating renal function with formulas

    NARCIS (Netherlands)

    Verhave, J.C.; Wetzels, J.F.M.; Bakker, S.J.; Gansevoort, R.T.

    2007-01-01

    A glomerular filtration rate (GFR) <60 ml/min/1.73 m2 is associated with an increased risk of cardiovascular disease and renal insufficiency. The formula of the 'Modification of diet in renal disease' (MDRD) study is derived from plasma-creatinine concentrations and estimates GFR based on age, sex

  10. Polyhydramnios and acute renal failure

    Science.gov (United States)

    Hamilton, D. V.; Kelly, Moira B.; Pryor, J. S.

    1980-01-01

    Acute renal failure secondary to ureteric obstruction is described in a primigravida with twin gestation and polyhydramnios. Relief of the obstruction occurred on drainage of the liquor and return to normal renal function following delivery. ImagesFig. 1 PMID:7022419

  11. Ultrasonography in chronic renal failure

    Energy Technology Data Exchange (ETDEWEB)

    Buturovic-Ponikvar, Jadranka E-mail: jadranka.buturovic@mf.uni-lj.si; Visnar-Perovic, Alenka

    2003-05-01

    Many chronic renal diseases lead to the final common state of decrease in renal size, parenchymal atrophy, sclerosis and fibrosis. The ultrasound image show a smaller kidney, thinning of the parenchyma and its hyperechogenicity (reflecting sclerosis and fibrosis). The frequency of renal cysts increases with the progression of the disease. Ultrasound generally does not allow for the exact diagnosis of an underlying chronic disease (renal biopsy is usually required), but it can help to determine an irreversible disease, assess prognosis and avoid unnecessary diagnostic or therapeutic procedures. The main exception in which the ultrasound image does not show a smaller kidney with parenchymal atrophy is diabetic nephropathy, the leading cause of chronic and end-stage renal failure in developed countries in recent years. In this case, both renal size and parenchymal thickness are preserved until end-stage renal failure. Doppler study of intrarenal vessels can provide additional information about microvascular and parenchymal lesions, which is helpful in deciding for or against therapeutic intervention and timely planning for optimal renal replacement therapy option.

  12. Acute renal failure after massive honeybee stings Insuficiência renal aguda após numerosas picadas de abelhas

    Directory of Open Access Journals (Sweden)

    Elizabeth De Francesco Daher

    2003-01-01

    Full Text Available Two clinical cases of patients who survived after numerous attacks of Africanized bees (600 and 1500 bee stings, respectively are reported. Clinical manifestation was characterized by diffuse and widespread edema, a burning sensation in the skin, headache, weakness, dizziness, generalized paresthesia, somnolence and hypotension. Acute renal failure developed and was attributed to hypotension, intravascular hemolysis, myoglobinuria due to rhabdomyolysis and probably to direct toxic effect of the massive quantity of injected venom. They were treated with antihistaminic, corticosteroids and fluid infusion. One of them had severe acute renal failure and dialysis was required. No clinical complication was observed during hospital stay and complete renal function recovery was observed in both patients. In conclusion, acute renal failure after bee stings is probably due to pigment nephropathy associated with hypovolemia. Early recognition of this syndrome is crucial to the successful management of these patients.Foram relatados dois casos clínicos de pacientes que sobreviveram a ataques maciços de abelhas africanizadas (600 e 1500 picadas. As reações caracterizaram-se por edema difuso e generalizado, sensação de queimação na pele, cefaléia, fraqueza, parestesia generalizada, sonolência e hipotensão. A insuficiência renal aguda desenvolveu-se, tendo sido atribuída à hipotensão, hemólise intravascular, mioglobinúria devido à rabdomiólise e provavelmente ao efeito tóxico direto da grande quantidade de veneno injetada. Os pacientes foram tratados com agentes anti-histamínicos, corticosteróides e reposição hídrica. Um paciente apresentou quadro grave de insuficiência renal aguda necessitando de tratamento dialítico. Nenhuma complicação clínica foi observada durante a internação e ambos evoluíram bem com recuperação completa da função renal. Assim, a insuficiência renal aguda após picadas de abelhas ocorre provavelmente

  13. Caracterización de la función renal en perros

    Directory of Open Access Journals (Sweden)

    Pedro Pablo Martínez Padua

    2012-06-01

    Full Text Available Mediante filtración, reabsorción y excreción, los riñones mantienen la homeostasis en los organismos vivos. Los perros con lesiones renales tienen afectados estos procesos, que alteran la homeostasis. Ello da como resultado cuadros de insuficiencia renal. Se evaluaron parámetros que estiman la filtración, reabsorción y excreción renal en tres grupos de perros, referentes a concentración sérica de creatinina, relación proteína-creatinina urinaria, clearance de creatinina, excreción fraccionada (EF de calcio, fósforo, sodio y magnesio, así como el perfil sérico de estos electrolitos. El grupo G1 estuvo conformado por diez perros sin alteración en los parámetros de función renal; quince perros con compromiso de función renal fueron distribuidos en dos grupos (G2 y G3, respectivamente, basados en las fases descritas por el IRIS 2009. Los grupos se compararon por el test de Kruskal-Wallis, seguido por el test de Dunn. Perros del G3 mostraron aumento de las concentraciones séricas de fósforo, sodio y magnesio, comparados con los G1 y G2. Perros de G1 y G2 presentaron disminución de la excreción fraccionada de los electrolitos, que difirieron de los perros del G3. Estos resultados sugieren que perros con afectación de la función renal presentan alteraciones que dependen de la gravedad y de la fase de la enfermedad. Estas alteraciones se evidenciaron en la EF de electrolitos en los diferentes grupos; adicionalmente, el Mg y el Na mostraron ser más sensibles al detectar precozmente el compromiso de la función renal.

  14. Apendicitis por Paracoccidioides brasiliensis

    Directory of Open Access Journals (Sweden)

    Ana Beatriz MUÑOZ URRIBARRI

    2006-01-01

    Full Text Available La paracoccidioidomicosis es la micosis más prevalente en Sudamérica. La forma aguda afecta el sistema fagocítico mononuclear de niños y personas inmunocomprometidas. El compromiso gastrointestinal es frecuente y su patogenia implica diseminación hematógena y linfática. La linfadenomegalia abdominal causa obstrucción intestinal y abdomen agudo. En este artículo damos a conocer el caso de un niño con compromiso gastrointestinal por apendicitis. Este es el primer caso reportado de apendicitis por esta patología. (Rev Med Hered 2006;17:58-60.

  15. Osteomielitis por salmonella

    Directory of Open Access Journals (Sweden)

    Alicia Velázquez Pérez

    2014-08-01

    Full Text Available Se presenta el caso de una paciente femenina de color blanco y dos años de edad, con diagnóstico prenatal de sicklemia, que desde edades tempranas tiene problemas de la enfermedad. Ingresó en esta ocasión por una de las complicaciones infecciosas que ocasiona este padecimiento, una osteomielitis del húmero izquierdo, aislándose el germen en el hemocultivo realizado, una salmonella. Necesitó de tratamiento enérgico y prolongado; se obtuvo un resultado satisfactorio en la evolución de la enfermedad y se sigue sistemáticamente por consulta externa en la actualidad

  16. Estatinas en enfermedad renal crónica

    Directory of Open Access Journals (Sweden)

    Rodrigo Andrés Sepúlveda Palamara

    2017-05-01

    Full Text Available La enfermedad renal crónica constituye una patología de prevalencia e impacto creciente en la población mundial por sus múltiples complicaciones, incluyendo un riesgo cardiovascular aumentado, que representa la principal causa de morbimortalidad en pacientes nefrópatas crónicos. Sin embargo, la relevancia de las dislipidemias, especialmente, la hipercolesterolemia LDL, en el deterioro de la función renal y desarrollo de ateroesclerosis en sujetos con daño renal crónico no ha sido claramente establecida. Esta situación ha generado controversia sobre el beneficio real del uso de hipolipemiantes en estos pacientes. En base a la evidencia disponible, incluyendo estudios clínicos recientes, la recomendación más apropiada sugiere que el uso de terapia hipolipemiante basada en estatinas (con o sin ezetimiba es beneficioso desde un punto de vista cardiovascular en nefrópatas crónicos con insuficiencia renal leve a moderada antes de la diálisis. Por otro lado, no existe evidencia definitiva para apoyar el uso rutinario de este tipo de hipolipemiantes en el manejo del deterioro de la filtración glomerular y/o la proteinuria. Basándose en la evidencia analizada en esta revisión, las futuras guías clínicas para el manejo del daño renal crónico deberán incorporar el uso de estatinas y/o ezetimiba como un elemento más dentro del armamento terapéutico de este tipo de pacientes.

  17. [Porphyrins in renal calculi (review)].

    Science.gov (United States)

    Traba Villameytide, Ma L

    2005-02-01

    We performed a review of the porphyrines content in a type of black, charcoal-like, renal calculi exhibiting infrared spectra (IRS) similar to those characteristic of "organic material" which has not yet been fully elucidate. Several other types of renal calculi, mainly those of small size, spontaneous passage renal stone, may also have diffuse or isolated dark charcoal components showing "organic material" IRS. After observing that haemoglobin has an "organic material" IRS, we studied, by a sensitive thin layer chromatography method, the presence of porphyrines in several types of dark or charcoal renal stones, since porphyrines are the physiological precursors of haemo group biosynthesis. We found two types of porphyrine content: coproporphyrin, in patients suffering from hepatopathy, and uroporphyrin and heptacarboxil-porphyrin in patients with some types of porphyria or with chronic renal failure.

  18. Fetal programming of renal function.

    Science.gov (United States)

    Dötsch, Jörg; Plank, Christian; Amann, Kerstin

    2012-04-01

    Results from large epidemiological studies suggest a clear relation between low birth weight and adverse renal outcome evident as early as during childhood. Such adverse outcomes may include glomerular disease, hypertension, and renal failure and contribute to a phenomenon called fetal programming. Other factors potentially leading to an adverse renal outcome following fetal programming are maternal diabetes mellitus, smoking, salt overload, and use of glucocorticoids during pregnancy. However, clinical data on the latter are scarce. Here, we discuss potential underlying mechanisms of fetal programming, including reduced nephron number via diminished nephrogenesis and other renal (e.g., via the intrarenal renin-angiotensin-aldosterone system) and non-renal (e.g., changes in endothelial function) alterations. It appears likely that the outcomes of fetal programming may be influenced or modified postnatally, for example, by the amount of nutrients given at critical times.

  19. Geriatric renal palliative care.

    Science.gov (United States)

    Swidler, Mark A

    2012-12-01

    Elderly patients with advanced chronic kidney disease or who are on dialysis should be able to live as fully and comfortably as possible. Geriatric patients are most interested in outcomes that will optimize mental and physical function and limit suffering and pain. Nephrologists must help them answer the question: "How will my kidney problem affect the way I live now and in the future?" This means management must move beyond glomerular filtration rate-related targets and incorporate geriatric principles that focus on assessment of function, comorbidities, geriatric syndromes, and quality of life issues. Therapeutic decisions should be individualized and directed by patient goals of care, which must be explored and documented. Accomplishing this requires inclusion of the patient's family-support system in the shared decision-making process. There is no substitute for spending time listening to and understanding the patient and family agenda, providing timely medical and prognostic updates; discussing realistic scenarios to balance expectations; and planting the seeds of change as the quantity and quality of medical events, geriatric syndromes, and comorbidities accumulate. Synergy of the interdisciplinary renal team with geriatric and palliative medicine specialists provides the expertise to achieve these goals. This falls into the domain of geriatric renal palliative or supportive care (1) and is the subject of this practical review.

  20. Carcel por amor

    OpenAIRE

    Torres, Carlos Luis

    2014-01-01

    La novela de Álvaro Pineda-Botero “Carcel por Amor”, una historia ligera en apariencia, relata la vida de l pintor Aurelio Méndez Tovar, y como se afirma en la nota “al lector”, la novela se escribe a solicitud de su hermana Gabriela (muerta hace poco tiempo) para aclarar ante el público las circunstancias que llevaron al pintor a su reclusión (en un sanatorio) y posterior muerte.

  1. A comparative study of ultrasonography, computed tomography and magnetic resonance imaging in the staging and invasion of adjacent structures by renal tumors; Estudo comparativo dos metodos de ultrassonografia, tomografia computadorizada e ressonancia magnetica no estadiamento e invasao das estruturas adjacentes por tumores renais

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, S.M.; Ajzen, S.A.; Trindade, J.C.S. [Universidade Federal de Sao Paulo (UNIFESP), SP (Brazil). Faculdade de Medicina; UNESP, Botucatu, SP (Brazil). Faculdade de Medicina; E-mail: sribeiro@fmb.unesp.br

    2001-09-01

    Ultrasonography (US), Computed Tomography (CT), and Magnetic Resonance imaging (MR) were compared for the staging of renal tumors. The differences between these imaging techniques were also studied for their ability to detect adenopathies, vascular invasion, distant intra-abdominal metastases, and particularly adjacent organ invasion. Thirty-one patients with solid or complex renal masses were prospectively studied using US, CT, and MR. Differences between the results obtained were studied using the Cochran G test and the Mc NEMAR test. The sensitivity and specificity of each diagnostic technique were compared against a 'gold standard' of the surgical and histopathological findings. The following sensitivities were obtained: For the detection of adenopathy, US 63.6%, CT and MR 90.9%. For vascular invasion, US 42.8%, CT and MR 85.7%. For the adjacent organ invasion, US 28.5%, CT 85.7%, and MR 71.4%. Some of the criteria that suggest invasion of adjacent structures include: the envelopment of the adjacent structures by the tumor, tumor extension into the adjacent structures with an irregular appearance, and alterations in shape, size, and density of adjacent structures. Loss of fat planes between the tumor and adjacent structures is not a sign of tumor invasion. Significant differences were found in the detection capacity of US in relation to CT and MR, which were similar. All three techniques were highly sensitive and specific only in the detection of distant abdominal metastases. In addition to the accuracy of these diagnostic modalities for the detection and staging of tumors, invasiveness, risks and cost should be considered in relation to relative costs and benefits. (author)

  2. Injúria Renal Aguda no paciente politraumatizado Acute Renal Injury in polytrauma patients

    Directory of Open Access Journals (Sweden)

    Thiago Gomes Romano

    2013-03-01

    Full Text Available A Injúria Renal Aguda (IRA no contexto do paciente politraumatizado ocorre, na maioria das vezes, por uma conjuntura de fatores que passam por eventos correlacionados à ressuscitação volêmica inicial, ao grau de resposta inflamatória sistêmica associada ao trauma, ao uso de contraste iodado para procedimentos diagnósticos, à rabdomiólise e à síndrome compartimental abdominal. Atualmente, passamos por uma fase de uniformização dos critérios diagnósticos da IRA com o Acute Kidney Injury Network (AKIN, sendo a referência mais aceita. Consequentemente, o estudo da IRA no politraumatismo também passa por uma fase de reformulação. Esta revisão da literatura médica visa trazer dados epidemiológicos, fisiológicos e de implicação clínica para o manuseio destes pacientes, bem como expor os riscos do uso indiscriminado de expansores volêmicos e particularidades sobre a instituição de terapia renal substitutiva em indivíduos sob risco de hipertensão intracraniana.Acute Kidney Injury (AKI in trauma is, in most cases, multifactorial. Factors related to the initial ressuscitation protocol, degree of the systemic inflamatory response to trauma, contrast nephropathy in diagnostic procedures, rhabdomyolysis and abdominal compartment syndrome are some of those factors. Nowadays a uniformization in diagnostic criteria for AKI has been proposed by the Acute Kidney Injury Network (AKIN and as a result the incidence of AKI and its impact in outcomes in trauma patients also needs to be reconsider. In this review we aim to approach epidemiologic, physiologic and clinical relevant data in the critical care of patients victims of trauma and also to expose the risks of indiscriminate use of volume expanders and the interaction between renal replacement theraphy and intracranial hypertension.

  3. Farmacodinâmica do cisatracúrio no transplante renal Farmacodinámica del cisatracúrio en el transplante renal Cisatracurium pharmacodynamics in renal transplantation

    Directory of Open Access Journals (Sweden)

    Ismar Lima Cavalcanti

    2002-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A escolha do cisatracúrio, especialmente nos doentes com insuficiência orgânica, parece ser benéfica, devido a sua eliminação órgão independente de Hofmann e menor tendência a liberar histamina. Este trabalho tem como objetivo determinar, em doentes portadores de insuficiência renal crônica, a farmacodinâmica do cisatracúrio durante o transplante renal. MÉTODO: Foram estudados 30 pacientes divididos em dois grupos, 15 com função renal normal submetidos a cirurgia bucomaxilo-facial e 15 portadores de insuficiência renal crônica submetidos a transplante renal sob anestesia geral com etomidato, sufentanil e sevoflurano em concentrações entre 0,5 e 1% de fração expirada. Receberam dose venosa de 0,15 mg.kg-1 de cisatracúrio na indução e 0,05 mg.kg-1 todas as vezes que T1 recuperava 25%. A função neuromuscular foi monitorizada de forma contínua por aceleromiografia utilizando o padrão de estimulação seqüência de quatro estímulos, através da estimulação supramáxima do nervo ulnar. RESULTADOS: Os resultados referentes à farmacodinâmica do cisatracúrio mostram que o início de ação (4,1 e 4,9 min, a duração clínica (68,9 e 75,4 min e o índice de recuperação (20,2 e 28 min foram semelhantes entre os grupos normal e insuficiência renal, respectivamente. Os tempos para a relação T4/T1 atingir 0,7 (34,3 e 51,4 min e 0,9 (49,7 e 68,6 min a partir do último 25% de T1 apresentaram diferença estatisticamente significante entre os grupos, com os maiores valores no grupo insuficiência renal. A razão de acumulação foi igual a 1,08. CONCLUSÕES: O início de ação, a duração clínica e o índice de recuperação são semelhantes entre os dois grupos, o tempo para a relação T4/T1 atingir 0,7 ou 0,9 foi maior no grupo insuficiência renal do que no grupo normal e o cisatracúrio não apresentou efeito acumulativo no grupo insuficiência renal.JUSTIFICATIVA Y OBJETIVOS: La escoja

  4. Avaliação prospectiva dos resultados a longo prazo da terapia intradiscal percutânea lombar por radiofrequência Evaluación prospectiva de resultados a largo plazo de la terapia intradiscal percutánea lumbar con radiofrecuencia Prospective evaluation of long-term results of percutaneous lumbar intradiscal radiofrequency therapy

    Directory of Open Access Journals (Sweden)

    Daniel Ferreira Ghedini

    2011-01-01

    Full Text Available OBJETIVO: Avaliar os resultados do tratamento da lombalgia crônica discogênica com a técnica IDET (Intradiscal Electrothermal Therapy em um acompanhamento maior que dois anos de pós-operatório (PO. MÉTODOS: Estudo prospectivo, avaliando 23 pacientes consecutivos com diagnóstico de lombalgia crônica discogênica tratados com IDET entre fevereiro de 2003 e fevereiro de 2006. A dor foi considerada discogênica em caso de discografia positiva ou imagem compatível com a ressonância magnética, segundo os critérios de Horton e Daftari. Os parâmetros clínicos (EVA e Oswestry foram avaliados no pré-operatório, no retorno com 6, 12, 18, 24 e mais de 48 meses de pós-operatório. RESULTADOS: A média de idade dos pacientes foi de 42,09 (variação de 26 a 51 anos. A média do período do acompanhamento foi de 32,55 meses (variação de 6 a 68 meses. A média do índice de dor (EVA foi de 7,07 ± 1,90, reduzindo-se para 2,47 ±1,876 em 6 meses, 2,69 ±1,82 em 12 meses, 3,63 ±1,75 em 18 meses e 5,73 ±2,12 em 24 meses. A média do índice Oswestry foi de 39,26 ± 11,96 no pré-operatório, reduzindo-se para 19,44±15,72 em 6 meses, 19,8 8 ±15,45 em 12 meses, 26,62 ±13,84 em 18 meses e 31,87 ±14,94 em 24 meses. Os resultados não se mantiveram no acompanhamento de 48 meses. CONCLUSÃO: O IDET mostrou resultados satisfatórios como alternativa paliativa no controle da dor e da incapacidade funcional num período de 24 meses. Os bons resultados deterioraram-se com 48 meses e houve uma tendência de retorno à sintomatologia inicial.OBJETIVO: Evaluar los resultados del tratamiento del lumbago crónico del disco usando la técnica IDET (electrotermocoagulación intradiscal en un seguimiento mayor que dos años de pos operatorio. MÉTODO: Estudio prospectivo, evaluando 23 pacientes, consecutivamente, con diagnóstico de lumbago crónico del disco tratados con IDET desde febrero de 2003 hasta febrero de 2006. El disco fue considerado como siendo la fuente del dolor en caso de discografia positiva o imagen compatible con la resonancia magnética según los criterios de Horton y Daftari. Los parámetros clínicos (EVA y Oswestry fueran evaluados en el pre operatorio, en el retorno, con 6, 12, 18, 24 y más de 48 meses de pos operatorio. RESULTADOS: El promedio de edad de los pacientes fue 42,09 años (variación de 26 a 51 años. El promedio del período del seguimiento fue 32,55 meses (variación de 6 a 68 meses. El promedio del Índice de Dolor (EVA fue de 7,07 ± 1,90 reduciéndose para 2,47 ±1,876 en 6 meses, 2,69 ±1,82 en 12 meses, 3,63 ±1,75 en 18 meses y 5,73 ±2,12 en 24 meses. El promedio del Índice Oswestry fue de 39,26 ± 11,96 pre operatorio reduciéndose para 19,44±15,72 en 6 meses, 19,8 8 ±15,45 en 12 meses, 26,62 ±13,84 en 18 meses y 31,87 ±14,94 en 24 meses. CONCLUSIÓN: La IDET mostró resultados satisfactorios como alternativa paliativa para el control del dolor y de la incapacidad funcional en un periodo de 24 meses. Los buenos resultados se deterioraron con 48 meses y hubo una tendencia de retorno de los síntomas iniciales.OBJECTIVES: Evaluate the results of treatment of patients with chronic discogenic low back pain who have been submitted to IDET (Intradiscal Electrothermal Therapy. Minimum post operatory follow up was two years. METHODS: Prospective study of 23 patients diagnosed with chronic discogenic low back pain who received treatment between February 2003 and February 2006. The disk was considered the source of the pain in case of a positive discography or a nuclear magnetic resonance image compatible with Horton and Daftari criteria. Clinical parameters (VAS and Oswestry were evaluated during pre-operatory and at 6, 12, 18, 24 and 48 months after surgery. RESULTS: The average age of patients was 42,09 years (26 to 51 years. The mean follow up time was 32,55 months (6 to 68 months. The mean visual analog scale (VAS was 7,07 ± 1,90, and was reduced to 2,47 ±1,876 at 6 months, 2,69 ±1,82 at 12 months, 3,63 ±1,75 at 18 months and 5,73 ± 2,12 at 24 months. Oswestry index average was 39,26 ± 11,96 before surgery. It was reduced to 19,44±15,72 6 months after surgery, 19,8 8 ±15,45 12 months, 26,62 ±13,84 18 months and 31,87 ±14,94 24 months after the procedure. Favorable results were not seen after a 48-month follow up. CONCLUSION: IDET technique has proved to be a good alternative in the palliative control of pain and functional incapacity during a 24-month period. Good results have deteriorated after 48 months, with a tendency to return of symptoms as they were prior to treatment.

  5. RENAL ONCOCYTOMA ASSOCIATED WITH RENAL CELL CARCINOMA : A CASE REPORT

    OpenAIRE

    荒井, 陽一; 田中, 陽一; 谷口, 隆信; 岡田, 裕作; 岡田, 謙一郎; 川村, 寿一

    1983-01-01

    We herein report a case of renal oncocytoma associated with renal cell carcmoma in the same kidney. A 78-year-old man was admitted for further examination of the right abdominal mass. Angiogram revealed two hypervascular renal tumors, one of which showed a "spoke-wheel" appearancc. Right nephrectomy was performed and two neoplasms were found, one in the upper pole which was diagnosed as clear cell carcinoma, and another in the mid-portion which was considered to fit the histologic criteria fo...

  6. Retroperitoneal and transperitoneal laparoscopic cryotherapy for small renal masses.

    Science.gov (United States)

    Domínguez, A; Bellido, J A; Muñoz-Rodríguez, J; Abascal-Junquera, J M; Hannaoui, N; Banús, J M

    2015-11-01

    Cryotherapy is a minimally invasive ablative technique that is considered an alternative to conventional surgery for preserving renal function in small renal tumors and in selected cases. We present our results from laparoscopic renal cryotherapy. We retrospectively analyzed 17 renal tumors diagnosed in 16 patients treated with cryotherapy. The patients' mean age was 66 years (43-80). The mean tumor size was 1.8cm (0.7-3.7cm). Cryotherapy with double-freeze cycle was performed laparoscopically in all cases (10 by transperitoneal approach and 7 by retroperitoneal approach). Perioperative biopsies were performed on all patients and were positive for malignancy in 10 cases (59%). The mean stay was 2.8 days. The mean operative time was 162 minutes. Only 1 case reverted to open surgery due to bleeding. One patient required a blood transfusion in the immediate postoperative period. The majority of complications were Clavien-Dindo grades I and II. Some 76.5% of the patients had no complications. After a mean follow-up of 31 months (6-102), 1 patient died from nontumor-related causes, and 12 patients (75%) still show no evidence of local recurrence or progression. One patient had tumor persistence and therefore underwent partial nephrectomy at 6 months. One patient had a metachronous recurrence in the same kidney at 36 months, and another patient had a recurrence at 23 months. Laparoscopic renal cryotherapy is a safe and feasible technique and is a good alternative to surgery for selected renal tumors. Copyright © 2015 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  7. RENAL DAMAGE WITH MALIGNANT NEOPLASMS

    Directory of Open Access Journals (Sweden)

    I. B. Kolina

    2015-01-01

    Full Text Available The relationship between renal damage and malignant neoplasms is one of the most actual problems of the medicine of internal diseases. Very often, exactly availability of renal damage determines the forecast of cancer patients. The range of renal pathologies associated with tumors is unusually wide: from the mechanical effect of the tumor or metastases on the kidneys and/or the urinary tract and paraneoplastic manifestations in the form of nephritis or amyloidosis to nephropathies induced with drugs or tumor lysis, etc. Thrombotic complications that develop as a result of exposure to tumor effects, side effects of certain drugs or irradiation also play an important role in the development of the kidney damage. The most frequent variants of renal damage observed in the practice of medical internists (therapists, urologists, surgeons, etc., as well as methods of diagnosis and treatment approaches are described in the article. Timely and successful prevention and treatment of tumor-associated nephropathies give hope for retaining renal functions, therefore, a higher life standard after completion of anti-tumor therapy. Even a shortterm episode of acute renal damage suffered by a cancer patient must be accompanied with relevant examination and treatment. In the caseof transformation of acute renal damage into the chronic kidney disease, such patients need systematic and weighted renoprotective therapy and correct dosing of nephrotoxic drugs.

  8. Renal Leiomyosarcoma: A Diagnostic Challenge

    Directory of Open Access Journals (Sweden)

    Jose R. Valery

    2013-01-01

    Full Text Available Renal leiomyosarcoma is a very rare tumor that clinically and radiographically mimics more common renal malignancies. The infrequency of the condition makes it very difficult to diagnose. A 70-year-old male smoker presented with months of hematuria, right-sided flank pain, and weight loss. Imaging revealed a 3.8-centimeter renal mass that had characteristics similar to renal cell carcinoma. Initial biopsy of the mass was negative for malignancy. Two months later, subsequent imaging revealed what appeared to be metastatic bone lesions. Again, a biopsy of one of the lesions was negative for malignancy. Subsequent ureteral pyeloscopy, ureteroscopic renal pelvis biopsy, and brush cytology were negative for malignancy as well. The decision was made to perform nephrectomy for the removal of the mass. Pathologic analysis revealed renal leiomyosarcoma. This case illustrates the difficulty in diagnosing renal leiomyosarcoma. Repeated pathologic sampling was negative because of the tumor heterogeneity. Prompt diagnosis and treatment are very significant as surgical resection at an early stage offers the best prognosis.

  9. Malignancy and chronic renal failure.

    Science.gov (United States)

    Peces, Ramon

    2003-01-01

    Increased incidence of cancer at various sites is observed in patients with end-stage renal disease (ESRD). Certain malignant diseases, such as lymphomas and carcinomas of the kidney, prostate, liver and uterus, show an enhanced prevalence compared with the general population. In particular, renal cell carcinoma (RCC) shows an excess incidence in ESRD patients. A multitude of factors, directly or indirectly associated with the renal disease and the treatment regimens, may contribute to the increased tumor formation in these patients. Patients undergoing renal replacement therapy (RRT) are prone to develop acquired cystic kidney disease (ACKD), which may subsequently lead to the development of RCC. In pre-dialysis patients with coexistent renal disease, as in dialysis and transplant patients, the presence of ACKD may predispose to RCC. Previous use of cytotoxic drugs (eg, cyclophosphamide) or a history of analgesic abuse, are additional risk factors for malignancy. Malignancy following renal transplantation is an important medical problem during the follow-up. The most common malignancies are lymphoproliferative disorders (early after transplantation) and skin carcinomas (late after transplantation). Another important confounder for risk of malignancy after renal transplantation is the type of immunosuppression. The type of malignancy is different in various countries and dependent on genetic and environmental factors. Finally, previous cancer treatment in a uremic patient on the transplant waiting list is of great importance in relation to waiting time and post-malignancy screening.

  10. Trasplante renal doble (TRD de donantes añosos

    Directory of Open Access Journals (Sweden)

    Pedro Méndez-Chacón

    2005-06-01

    Full Text Available Objetivo: Utilizar ambos riñones del donante añoso en un mismo receptor y resaltar la importancia de la histología renal como método seleccionador. Materiales y Métodos: Se evalúa la elección y seguimiento de 11 pacientes quienes recibieron riñones dobles de donantes cadavéricos añosos. La creatinina sérica promedio de los 11 donantes fue de 1,3 mg%, cursando con edades promedio de 63 años (56 a 73 y de 53 años en los receptores. Ambos riñones fueron sometidos a biopsia en cuña por congelación. La cuantificación del tejido dañado se basó en metodología ya definida. Riñones con lesiones microscópicas moderadas (puntaje 4 a 6/12 fueron seleccionados para trasplante renal doble. Estos fueron implantados extraperitonealmente en cada fosa ilíaca con anastomosis a vasos ilíacos externos y ambos uréteres por separado a la vejiga. Esteroides y micofenolato de mofetil conformaron el esquema inmunosupresor de primera línea. Resultados: Ningún receptor requirió hemodiálisis postrasplante. Nueve de los once receptores cursan con función renal aceptable a dos años promedio de seguimiento. Un receptor falleció por accidente cerebrovascular (ACV hemorrágico a los 36 meses del trasplante con injerto funcionante y otro presentó enfermedad neoplásica a 38 meses del postimplante. Conclusiones: El trasplante renal doble de donante añoso constituye opción inédita en nuestro medio para receptores añosos. Resaltamos la histología renal como método en la elección del donante. Futuras investigaciones mostrarán si el trasplante renal doble, incrementando la masa nefronal, sirva para demorar o prevenir la disfunción crónica del injerto a largo plazo.

  11. Hyperparathyroidism of Renal Disease.

    Science.gov (United States)

    Yuen, Noah K; Ananthakrishnan, Shubha; Campbell, Michael J

    2016-01-01

    Renal hyperparathyroidism (rHPT) is a common complication of chronic kidney disease characterized by elevated parathyroid hormone levels secondary to derangements in the homeostasis of calcium, phosphate, and vitamin D. Patients with rHPT experience increased rates of cardiovascular problems and bone disease. The Kidney Disease: Improving Global Outcomes guidelines recommend that screening and management of rHPT be initiated for all patients with chronic kidney disease stage 3 (estimated glomerular filtration rate, < 60 mL/min/1.73 m(2)). Since the 1990s, improving medical management with vitamin D analogs, phosphate binders, and calcimimetic drugs has expanded the treatment options for patients with rHPT, but some patients still require a parathyroidectomy to mitigate the sequelae of this challenging disease.

  12. Tuberculosis After Renal Transplant.

    Science.gov (United States)

    Barbouch, Samia; Hajji, Meriam; Helal, Imed; Ounissi, Mondher; Bacha, Mohammed Mongi; Ben Hamida, Fathi; Abderrahim, Ezzedine; Ben Abdallah, Taieb

    2017-02-01

    Tuberculosis is one of the leading infections after renal transplant, particularly in developing countries where the incidence and prevalence in the general population are high. Diagnosis requires bacteriologic and histologic confirmation. Interactions among the antitubercular drugs and the immunosuppressive agents have to be considered while prescribing, and surveillance for adverse effects is required. Although rare, case reports are available on extrapulmonary tuberculosis in allograft recipients. Here, we present a 25-year-old kidney transplant recipient who was diagnosed with lymph node tuberculosis under uncommon circumstances but who had a good outcome. This case report illustrates the difficulties in diagnosis of tuberculosis, changes in therapeutic protocols, and prognostic factors and highlights the effects of infectious complications with immunosuppressive therapy in this particular patient population.

  13. Diagnosis and treatment of renal artery stenosis.

    NARCIS (Netherlands)

    Plouin, P.F.; Bax, L.

    2010-01-01

    A reduction in the diameter of the renal arteries can lead to hypertension, renal dysfunction and/or pulmonary edema. About 90% of patients with renal artery stenosis have atherosclerosis, and 10% have fibromuscular dysplasia. Atherosclerotic renal artery stenosis is a common condition that

  14. Renal acidification defects in medullary sponge kidney

    DEFF Research Database (Denmark)

    Osther, P J; Hansen, A B; Røhl, H F

    1988-01-01

    Thirteen patients with medullary sponge kidney underwent a short ammonium chloride loading test to investigate their renal acidification capacity. All but 1 presented with a history of recurrent renal calculi and showed bilateral widespread renal medullary calcification on X-ray examination. Nine...... of renal calculi in medullary sponge kidney, have considerable therapeutic implications....

  15. Renal cell carcinoma with melanin pigment

    Science.gov (United States)

    Shetty, Jayaprakash; Chandrika; Laxman, Prabhu

    2010-01-01

    The incidence of renal cell carcinoma has been steadily increasing. There are several morphological types of renal cell carcinoma. Recognizing histologic patterns of renal cell carcinoma is important for correct diagnosis and subsequent medical care for the patient. Melanotic tumors in the kidney are very rare. Here, we present an unusual case of renal cell carcinoma with melanin pigment. PMID:20877613

  16. Primary renal osteosarcoma: A case report

    African Journals Online (AJOL)

    C. Ahomadégbé

    features of a case of primary renal osteosarcoma in a 56-year-old man with stage IV disease. This is the. 28th case of primitive renal ... parenchyma and infiltrated the renal capsule and perirenal fat with- out involvement of the adrenal ... There was a breach of the renal capsule and infiltration of the perirenal fat. The hilum ...

  17. Hematoma subcapsular por Fasciolasis

    OpenAIRE

    MORALES G,JUAN L; ARRIAGADA H,RENATO; SALAS G,LUIS; MORALES A,CARLOS; FUENTES A,FELIPE; Santana, Roberto

    2009-01-01

    Presentamos el caso de una paciente de sexo femenino de 60 años de edad, ingresada en nuestro centro hospitalario por cuadro agudo de dolor abdominal en hipocondrio derecho asociado a vómitos y fiebre. Destaca la presencia de leucocitosis con eosinofilia de 56%. La tomografía computanzada abdominal muestra una colección subcapsular hepática. Durante su evolución presenta abdomen agudo, realizándose una laparoscopía exploratoria que confirma un hematoma subcapsular con presencia de hemopentone...

  18. Infecciones por citomegalovirus

    Directory of Open Access Journals (Sweden)

    Ana Gloria Díaz Martínez

    1998-06-01

    Full Text Available Se ofrece una revisión actualizada sobre la infección por citomegalovirus a partir de la consulta de artículos referidos de 1990 a 1996 en las bases de datos MEDLINE, LILACS, Literatura Cubana de Medicina y Noticias de Salud. Se revisaron 37 artículos. Se abordan los aspectos más importantes de las manifestaciones clínicas, el diagnóstico, el tratamiento, así como la prevención y los métodos de control para evitar las enfermedades citomegálicas

  19. Osteomielitis por salmonella

    OpenAIRE

    Alicia Velázquez Pérez; Teresa P. Rodríguez Torres; Orelvis Pérez Duerto

    2014-01-01

    Se presenta el caso de una paciente femenina de color blanco y dos años de edad, con diagnóstico prenatal de sicklemia, que desde edades tempranas tiene problemas de la enfermedad. Ingresó en esta ocasión por una de las complicaciones infecciosas que ocasiona este padecimiento, una osteomielitis del húmero izquierdo, aislándose el germen en el hemocultivo realizado, una salmonella. Necesitó de tratamiento enérgico y prolongado; se obtuvo un resultado satisfactorio en la evolución de la enferm...

  20. Combates por la historia

    OpenAIRE

    2015-01-01

    E.P.S. Huayco frente a Sarita Colonia. 1980. De izquierda a derecha: Charo Noriega, Mariela Zevallos, Herbert Rodríguez, María Luy y Francisco Mariotti flanqueado por sus hijas. No aparecen Juan Javier Salazar y Armando Williams.(Fotografía: ¿AW?). Diecinueve anos después. De izquierda a derecha: Armando Williams, Francisco Mariotti, Charo Noriega y Juan Javier Salazar. (Fotografía: GB). Correctamente asumida, sin embargo, esta cercanía personal puede ser favorable para la reconstrucción min...

  1. Por mil devaluados pesos

    Directory of Open Access Journals (Sweden)

    Annie Rodríguez Collázos

    2013-03-01

    Full Text Available El estudio de lo popular y lo urbano hasta ahora se ha centrado en el comportamiento y en algunas relaciones de los habitantes con su entorno. “Por mil devaluados pesos. Publicidad popular y urbana”, pretende explorar las formas de publicidad, dispersas en diferentes espacios populares y urbanos en Bogotá, identificando esquemas y formas características de sus propios códigos comunicativos; se centran en un objeto de estudio consistente en las estrategias publicitarias y los códigos comunicativos en los mensajes publicitarios populares en las subculturas de San Victorino, 7 de Agosto y Sanandresito de San José.

  2. Characterization of complex renal cysts

    DEFF Research Database (Denmark)

    Graumann, Ole; Osther, Susanne Sloth; Osther, Palle Jörn Sloth

    2010-01-01

    Abstract Objective. Complex renal cysts represent a major clinical problem, since it is often difficult to exclude malignancy. The Bosniak classification system, based on computed tomography (CT), is widely used to categorize cystic renal lesions. The aim of this study was to evaluate critically...... available data on the Bosniak classification. Material and methods. All publications from an Entrez Pubmed search were reviewed, focusing on clinical applicability and the use of imaging modalities other than CT to categorize complex renal cysts. Results. Fifteen retrospective studies were found. Most...

  3. Renal rickets-practical approach

    Directory of Open Access Journals (Sweden)

    Manisha Sahay

    2013-01-01

    Full Text Available Rickets/osteomalacia is an important problem in a tropical country. Many cases are due to poor vitamin D intake or calcium deficient diets and can be corrected by administration of calcium and vitamin D. However, some cases are refractory to vitamin D therapy and are related to renal defects. These include rickets of renal tubular acidosis (RTA, hypophosphatemic rickets, and vitamin D dependent rickets (VDDR. The latter is due to impaired action of 1α-hydroxylase in renal tubule. These varieties need proper diagnosis and specific treatment.

  4. Rol de las claudinas en el manejo renal del calcio

    Directory of Open Access Journals (Sweden)

    Armando Luis Negri

    2015-07-01

    Full Text Available Los canales paracelulares que se encuentran en las uniones estrechas tienen un papel fundamental en los flujos iónicos transepiteliales. Esta vía está formada por un gran número de proteínas, entre ellas, las claudinas. En el epitelio renal, las claudinas confieren selectividad iónica a la unión estrecha. La rama gruesa ascendente de Henle (RGAH es el segmento tubular renal más importante en la reabsorción tubular de calcio. Sus células forman una barrera impermeable al agua, transportan activamente sodio y cloro por la vía transcelular y proveen una vía paracelular para la reabsorción selectiva de calcio. Varios estudios han llevado a un modelo en el que distintas claudinas forman el canal paracelular, especialmente la claudina 16 y 19. La claudina 16 media la permeabilidad paracelular catiónica en la RGAH mientras que la claudina 19 incrementa la selectividad catiónica de la claudina 16 bloqueando la permeabilidad aniónica. Recientemente se ha encontrado que la actividad promotora de la claudina 14 está localizada exclusivamente en la RAGH. Cuando se coexpresa con la claudina 16, la claudina 14 inhibe la permeabilidad de la claudina 16, reduciendo la permeabilidad paracelular al calcio. El proceso de reabsorción de calcio en la RGAH está estrechamente regulado por el receptor sensor de calcio (CaSR que monitorea los niveles circulantes de Ca ajustando la tasa de excreción renal de forma acorde. Dos micro-ARN, los mir-9 y mir-374, son regulados directamente por el CaSR. Los miR-9 y miR-374 suprimen la traslación del ARNm de la claudina 14 e inducen su decaimiento.

  5. Management of renal disease in pregnancy.

    Science.gov (United States)

    Podymow, Tiina; August, Phyllis; Akbari, Ayub

    2010-06-01

    Although renal disease in pregnancy is uncommon, it poses considerable risk to maternal and fetal health. This article discusses renal physiology and assessment of renal function in pregnancy and the effect of pregnancy on renal disease in patients with diabetes, lupus, chronic glomerulonephritis, polycystic kidney disease, and chronic pyelonephritis. Renal diseases occasionally present for the first time in pregnancy, and diagnoses of glomerulonephritis, acute tubular necrosis, hemolytic uremic syndrome, and acute fatty liver of pregnancy are described. Finally, therapy of end-stage renal disease in pregnancy, dialysis, and renal transplantation are reviewed. Copyright 2010 Elsevier Inc. All rights reserved.

  6. Hemodinâmica glomerular renal no roedor Calomys callosus

    Directory of Open Access Journals (Sweden)

    Mirian A. Boim

    1989-03-01

    Full Text Available A função renal do roedor Calomys callosus, envolvido no ciclo de transmissão de diversos agentes patogênicos para o homem foi avaliada no animal intacto, através da técnica de depuração e micropunção renal. Os resultados mostraram que este roedor apresenta níveis pressóricos, hematócrito e proteinas plasmáticas semelhantes aos dos ratos submetidos ao mesmo procedimento experimental. Os pesos corporal e renal, bem como a filtração glomerular global e por nefro assemelham-se aos do camundongo. Surpreendentemente estes roedores apresentaram significante número de glomérulos superficiais por rim, permitindo a avaliação da hemodinàmica glomerular. Apesar da pressão arterial semelhante à dos ratos Munich-Wistar (MW, a pressão hidráulica intraglomerular no Calomys callosus foi inferior. Esta redução foi conseqüente à menor resistência pós-glomerular quando comparada à dos ratos MW. O fluxo plasmático glomerular atingiu valor bastante elevado em relação à filtração glomerular por nefro, fato que não só compensaria a reduzida pressão intraglomerular, como também seria suficiente para elevar a filtração (por g/rim a níveis superiores neste roedor, pois o coeficiente de ultrafiltração glomerular (Kj foi semelhante ao do rato MW. O presente trabalho sugere que apesar das dificuldades técnicas que este animal impõe devido ao seu reduzido tamanho, o estudo da função renal global bem como da hemodinàmica glomerular é factível, podendo portanto ser utilizado como modelo para estudo da função renal em doenças tropicais.

  7. MRI features of renal oncocytoma and chromophobe renal cell carcinoma.

    Science.gov (United States)

    Rosenkrantz, Andrew B; Hindman, Nicole; Fitzgerald, Erin F; Niver, Benjamin E; Melamed, Jonathan; Babb, James S

    2010-12-01

    The purpose of this study was to retrospectively describe the MRI features of the pathologically related entities renal oncocytoma and chromophobe renal cell carcinoma (RCC). Twenty-eight cases of histologically proven renal oncocytoma and 15 of chromophobe RCC evaluated with preoperative MRI from January 2003 through June 2009 at our institution were independently reviewed for an array of MRI features by two radiologists blinded to the final histopathologic diagnosis. These features were tabulated and compared between chromophobe RCC and renal oncocytoma by use of the Mann-Whitney test and binary logistic regression. Renal oncocytoma and chromophobe RCC showed no significant difference in size or any of 16 qualitative imaging features (p = 0.0842-1.0, reader 1; p = 0.0611-1.0, reader 2). Microscopic fat, hemorrhage, cysts, infiltrative margins, perinephric fat invasion, renal vein invasion, enhancement homogeneity, and hypervascularity were each observed in less than 20% of cases by both readers. A central scar and segmental enhancement inversion (a recently described finding in which early contrast-enhanced images show relatively more enhanced and less enhanced intralesional components with inversion of their relative enhancement on later images) were observed by both readers in at least 10% of cases of both renal oncocytoma and of chromophobe RCC with no significant difference between the two entities (p = 0.2092-0.2960). We have presented the largest series to date of the MRI features of both renal oncocytoma and chromophobe RCC. These related entities exhibited similar findings, and no MRI features were reliable in distinguishing between them.

  8. Resposta renal à maltodextrina e ao treinamento em diferentes intensidades

    Directory of Open Access Journals (Sweden)

    Cátia Fernandes Leite

    2015-03-01

    Full Text Available O objetivo foi investigar a resposta renal à ingestão de maltodextrina e à natação de padrão aeróbio ou anaeróbio de alta intensidade em ratos. Materiais e métodos O protocolo consistiu de oito semanas de natação em padrão aeróbio (sobrecarga 5% ou intermitente (sobrecarga 10%. Durante 37 dias os animais foram suplementados, por meio de gavagem, com uma dose diária de 0,48g.Kg−1 de maltodextrina dissolvida em água ou receberam água pura, antes do treinamento. Resultados O treinamento anaeróbio ocasionou aumento nas concentrações de ácido úrico, creatinina e proteínas totais e redução no glicogênio renal. A maltodextrina causou aumento no glicogênio renal. Conclusão A maltodextrina e o treinamento anaeróbio proporcionaram alterações nos parâmetros de função renal em resposta desse órgão a esses estímulos externos.

  9. Treatment of caval vein thrombosis associated with renal tumors.

    Science.gov (United States)

    Jiménez-Romero, Carlos; Conde, María; de la Rosa, Federico; Manrique, Alejandro; Calvo, Jorge; Caso, Óscar; Muñoz, Carlos; Marcacuzco, Alberto; Justo, Iago

    2017-03-01

    Renal carcinoma represents 3% of all solid tumors and is associated with renal or inferior caval vein (IVC) thrombosis between 2-10% of patients, extending to right atrial in 1% of cases. This is a retrospective study that comprises 5 patients who underwent nephrectomy and thrombectomy by laparotomy because of renal tumor with IVC thrombosis level iii. Four patients were males and one was female, and the mean age was 57,2 years (range: 32-72). Most important clinical findings were hematuria, weight loss, weakness, anorexia, and pulmonary embolism. Diagnostic confirmation was performed by CT scanner. Metastatic disease was diagnosed before surgery in 3 patients. Suprahepatic caval vein and hepatic hilium (Pringle's maneouver) were clamped in 4 patients, and ligation of infrarrenal caval vein was carry out in one patient. Five patients developed mild complications (Clavien I/II). No patient died and the mean hospital stay was 8,6 days. All patients were treated with chemotherapy, and 3 died because distant metastasis, but 2 are alive, without recurrence, at 5 and 60 months, respectively. Nephrectomy and thrombectomy in renal tumors with caval thrombosis can be curative in absence of metastasis or, at less, can increase survival or quality of live. Then these patients must be treated in liver transplant units because major surgical and anesthesiologic expertise. Adjuvant treatment with tyrosin kinase inhibitors must be validate in the future with wider experiences. Copyright © 2017 AEC. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Vasculitis inducida por metimazol: Reporte de caso

    Directory of Open Access Journals (Sweden)

    Miguel Pinto

    2011-07-01

    Full Text Available Se reporta el caso de una paciente con enfermedad de Graves, que presentó vasculitis asociada al uso de metimazol. Mujer de 14 años, que acudió a consulta por presentar intolerancia al calor, tremor distal y palpitaciones. El examen físico mostró bocio difuso, y el perfil tiroideo, TSH suprimida y hormonas tiroideas elevadas. Los anticuerpos antiperoxidasa tiroidea fueron positivos. Se inició tratamiento con metimazol y beta bloqueadores. Después de 20 días, la paciente regresó por presentar malestar general, fiebre, poliartralgia, lesiones cutáneas maculopapulares y edema de miembros inferiores. Los anticuerpos antinucleares fueron negativos y los anticuerpos anticitoplasma de los neutrófilos (ANCA, positivos. Se suspendió el metimazol y se inició prednisona. Después de 10 días de tratamiento, las molestias desaparecieron y la paciente recibió I 131.Las vasculitis asociadas al uso de tionamidas son poco frecuentes, no dependen de la dosis y están asociadas a la presencia de anticuerpos tipo ANCA. Clásicamente, afectan a los vasos pequeños de la piel; sin embargo, también pueden afectar los riñones y pulmones. El cuadro clínico se caracteriza por artralgias y mialgias. En algunos casos puede ocurrir insuficiencia renal de grado variable. En la mayoría de casos, el cuadro remite con la suspensión de la droga; pero, en algunos se requiere el uso de glucocorticoides o inmunosupresores.(Rev Med Hered 2011;22:147-150.

  11. Índice de resistividade renal como preditor da revascularização renal para hipertensão renovascular Índice de resistividad renal como predictor de la revascularización renal para hipertensión renovascular Renal resistance index predicting outcome of renal revascularization for renovascular hypertension

    Directory of Open Access Journals (Sweden)

    Simone N. Santos

    2010-04-01

    Full Text Available FUNDAMENTO: A estenose arterial renal (EAR é uma causa potencialmente reversível de hipertensão arterial sistêmica (HAS e nefropatia isquêmica. Apesar da revascularização bem sucedida, nem todos os pacientes (pt apresentam melhora clínica e alguns podem piorar. OBJETIVO: O presente estudo se destina a avaliar o valor do índice de resistividade renal (IR como preditor dos efeitos da revascularização renal. MÉTODOS: Entre janeiro de 1998 e fevereiro de 2001, 2.933 pacientes foram submetidos ao duplex ultrassom renal. 106 desses pacientes apresentaram EAR significativa e foram submetidos a angiografia e revascularização renal. A pressão arterial (PA foi medida antes e depois da intervenção, em intervalos de até 2 anos e as medicações prescritas foram registradas. Antes da revascularização, o IR foi medido em 3 locais do rim, sendo obtida uma média dessas medições. RESULTADOS: Dos 106 pacientes, 81 tiveram IR80. A EAR foi corrigida somente por angioplastia (PTA em 25 pts, PTA + stent em 56 pts e cirurgicamente em 25 pts. Dos pacientes que se beneficiaram da revascularização renal; 57 dos 81 pacientes com IR 80. Usando um modelo de regressão logística múltipla, o IR esteve significativamente associado à evolução da PA (p = 0,001, ajustado de acordo com os efeitos da idade, sexo, PAS, PAD, duração da hipertensão, o tipo de revascularização, número de fármacos em uso, nível de creatinina, presença de diabete melito, hipercolesterolemia, volume sistólico, doença arterial periférica e coronariana e tamanho renal (OR 99,6-95%CI para OR 6,1-1.621,2. CONCLUSÃO: A resistividade intrarrenal arterial, medida por duplex ultrassom, desempenha um papel importante na predição dos efeitos pós revascularização renal para EAR.FUNDAMENTO: La estenosis arterial renal (EAR es una causa potencialmente reversible de hipertensión arterial sistémica (HAS y nefropatía isquémica. Pese a que la revascularización sea

  12. The Effects of Renal Denervation on Renal Hemodynamics and Renal Vasculature in a Porcine Model

    Science.gov (United States)

    Verloop, Willemien L.; Hubens, Lisette E. G.; Spiering, Wilko; Doevendans, Pieter A.; Goldschmeding, Roel; Bleys, Ronald L. A. W.; Voskuil, Michiel

    2015-01-01

    Rationale Recently, the efficacy of renal denervation (RDN) has been debated. It is discussed whether RDN is able to adequately target the renal nerves. Objective We aimed to investigate how effective RDN was by means of functional hemodynamic measurements and nerve damage on histology. Methods and Results We performed hemodynamic measurements in both renal arteries of healthy pigs using a Doppler flow and pressure wire. Subsequently unilateral denervation was performed, followed by repeated bilateral hemodynamic measurements. Pigs were terminated directly after RDN or were followed for 3 weeks or 3 months after the procedure. After termination, both treated and control arteries were prepared for histology to evaluate vascular damage and nerve damage. Directly after RDN, resting renal blood flow tended to increase by 29±67% (P = 0.01). In contrast, renal resistance reserve increased from 1.74 (1.28) to 1.88 (1.17) (P = 0.02) during follow-up. Vascular histopathology showed that most nerves around the treated arteries were located outside the lesion areas (8±7 out of 55±25 (14%) nerves per pig were observed within a lesion area). Subsequently, a correlation was noted between a more impaired adventitia and a reduction in renal resistance reserve (β: -0.33; P = 0.05) at three weeks of follow-up. Conclusion Only a small minority of renal nerves was targeted after RDN. Furthermore, more severe adventitial damage was related to a reduction in renal resistance in the treated arteries at follow-up. These hemodynamic and histological observations may indicate that RDN did not sufficiently target the renal nerves. Potentially, this may explain the significant spread in the response after RDN. PMID:26587981

  13. Nuevos anticoagulantes orales en pacientes con enfermedad renal crónica

    National Research Council Canada - National Science Library

    Belmar Vega, Lara; de Francisco, A.L.M; Bada da Silva, Jairo; Galván Espinoza, Luis; Fernández Fresnedo, Gema

    Los pacientes con enfermedad renal crónica (ERC) tienen tendencias hemorrágicas y trombóticas, por lo que la indicación de anticoagulación ante la aparición de fibrilación auricular (FA) es compleja...

  14. Genetics Home Reference: renal hypouricemia

    Science.gov (United States)

    ... lead to episodes of blood in the urine (hematuria). Rarely, people with renal hypouricemia develop life-threatening ... Institute of Diabetes and Digestive and Kidney Diseases: Hematuria (Blood in the Urine) National Institute of Diabetes ...

  15. Contemporary treatment of renal tumors

    DEFF Research Database (Denmark)

    Nisen, Harry; Järvinen, Petrus; Fovaeus, Magnus

    2017-01-01

    Objective: The five Nordic countries comprise 25 million people, and have similar treatment traditions and healthcare systems. To take advantage of these similarities, a collaborative group (Nordic Renal Cancer Group, NORENCA) was founded in 2015. Materials and methods: A questionnaire of 17...... questions on renal tumor management and surgical education was designed and sent to 91 institutions performing renal tumor surgery in 2015. The response rate was 68% (62 hospitals), including 28 academic, 25 central and nine district hospitals. Hospital volume was defined as low (LVH: ..., black box or animal laboratory was possible in 48%, 74% and 21% of institutions, respectively. Conclusions: Despite some differences between countries, the data suggest an overall general common Nordic treatment attitude for renal tumors. Furthermore, the data demonstrate high adherence to international...

  16. Plasma metanephrines in renal failure.

    NARCIS (Netherlands)

    Eisenhofer, G.; Huysmans, F.T.M.; Pacak, K.; Walther, M.M.; Sweep, C.G.J.; Lenders, J.W.M.

    2005-01-01

    BACKGROUND: Diagnosis of pheochromocytoma in renal failure poses a diagnostic dilemma due to lack of reliability of conventional urinary measurements of catecholamine excess. Measurements of the plasma metanephrines, normetanephrine and metanephrine (the O-methylated metabolites of norepinephrine

  17. Primary renal and retroperitoneal actinomycosis

    Energy Technology Data Exchange (ETDEWEB)

    Horvath, K.; Palko, A. [Szent-Gyoergyi Albert Medical University, Department of Radiology, Szeged (Hungary); Porkolab, Z. [Dept. of Urology, Josa A. County Hospital, Szent (Hungary)

    2000-02-01

    A case of the rare condition of renal and retroperitoneal actinomycosis is presented. The clinical and imaging (ultrasonography and computed tomography) findings are described and attention is drawn to the diagnostic difficulties in this rare disease. (orig.)

  18. Cryoablation for Small Renal Masses

    Directory of Open Access Journals (Sweden)

    J. L. Dominguez-Escrig

    2008-01-01

    Full Text Available Advances in imaging techniques (CT and MRI and widespread use of imaging especially ultrasound scanning have resulted in a dramatic increase in the detection of small renal masses. While open partial nephrectomy is still the reference standard for the management of these small renal masses, its associated morbidity has encouraged clinicians to exploit the advancements in minimally invasive ablative techniques. The last decade has seen the rapid development of laparoscopic partial nephrectomy and novel ablative techniques such as, radiofrequency ablation (RFA, high-intensity focused ultrasound (HIFU, and cryoablation (CA. In particular, CA for small renal masses has gained popularity as it combines nephron-sparing surgery with a minimally invasive approach. Studies with up to 5-year followup have shown an overall and cancer-specific 5-year survival of 82% and 100%, respectively. This manuscript will focus on the principles and clinical applications of cryoablation of small renal masses, with detailed review of relevant literature.

  19. Renal abscess caused by Brucella

    Directory of Open Access Journals (Sweden)

    Jun Li

    2014-11-01

    Full Text Available Involvement of the renal parenchyma in the acute phase of brucellosis is very rare. Only two cases of renal brucelloma have been reported in the English language literature to date. We report a case of renal abscess caused by Brucella in the acute phase. A 45-year-old Chinese man presented with a high fever, urine occult blood, and a low density lesion in the right kidney. Ultrasound-guided aspiration was done. Brucella melitensis was isolated from both blood and puncture fluid culture. Minocycline combined with moxifloxacin was prescribed for 4 months. The infection relapsed at 6 months after discontinuation. Minocycline combined with rifampin was administered for another 2 months. The brucellosis had not relapsed at more than 20 months later. It is possible to cure renal brucelloma with antibiotics and ultrasound-guided aspiration. Treatment should not be discontinued until the abscess has disappeared and two consecutive blood cultures taken 1 month apart are negative.

  20. [Renal involvement in systemic sclerosis].

    Science.gov (United States)

    Jara, Luis J; Barrera, Antonio

    2006-11-01

    Renal crisis is one of the most severe complications of systemic sclerosis, and its frequency is 10%, and it is characterized by malignant hypertension, hyperreninemia, azotemia, microangiopathic hemolytic anemia, and renal failure. In the pathogenesis of renal affection, the main mechanism is the endothelial damage (thickness of arterial vessels), decrease of blood flow and hyperplasia of the yuxtaglomerular apparatus as well as release of renina. Pathological changes of scleroderma kidney are similar to those observed in other forms of malignant hypertension. Renal crisis was considered as fatal complications, however it is now successfully treated with angiotensin- converting enzyme inhibitors. Copyright © 2006 Elsevier España S.L. Barcelona. Published by Elsevier Espana. All rights reserved.

  1. Renal infarction complicating fibromuscular dysplasia.

    Science.gov (United States)

    Gavalas, M; Meisner, R; Labropoulos, N; Gasparis, A; Tassiopoulos, A

    2014-01-01

    Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory vascular disease that most commonly affects the renal and extracranial carotid arteries. We present 3 cases of renal infarction complicating renal artery FMD in 42-, 43-, and 46-year-old females and provide a comprehensive review of the literature on this topic. In our patients, oral anticoagulation therapy was used to treat all cases of infarction, and percutaneous angioplasty was used nonemergently in one case to treat refractory hypertension. All patients remained stable at 1-year follow-up. This is consistent with outcomes in previously published reports where conservative medical management was comparable to surgical and interventional therapies. Demographic differences may also exist in patients with renal infarction and FMD. A higher prevalence of males and a younger age at presentation have been found in these patients when compared to the general population with FMD. © The Author(s) 2014.

  2. Transcatheter embolisation of renal angiomyolipoma.

    LENUS (Irish Health Repository)

    Leong, S

    2010-06-01

    Angiomyolipomas (AML) are rare benign renal tumours which are associated with aneurysms that can cause haemorrhage. Embolisation of AML greater than 4 cm with a variety of embolic agents is now the first-line treatment in these cases.

  3. Denervación renal percutánea mediante el uso de catéter con balón en pacientes con hipertensión arterial resistente

    Directory of Open Access Journals (Sweden)

    Isabel C. Marín-Orozco

    2015-11-01

    El objetivo del presente reporte es describir detalladamente dos casos de hipertensión arterial resistente, tratados mediante ablación con radiofrecuencia con el nuevo dispositivo Vessix® de la compañía Boston Scientific.

  4. Renal biopsy in the elderly

    Directory of Open Access Journals (Sweden)

    Javier Robaina

    2016-09-01

    Full Text Available Introduction: Kidney disease is very common among the elderly. Over the last decades, the number of renal biopsies performed on these patients has increased. Objective: This study was carried out to examine the frequency and the clinical-pathological correlation of kidney disease in elderly patients who have had a renal biopsy done. Methods: The clinical presentation of kidney disease and the main histological findings were retrospectively analyzed in patients over 65 who had undergone renal biopsy (n=109 for a period of 12 years. Results: The total number of renal biopsies performed during this period was 871, out of which 109 (12.5% corresponded to patients over 65. The main indications for renal biopsies were nephrotic syndrome (37.6% and kidney failure (34.9%. Microscopic hematuria was found in 59.6% of the patients and high blood pressure in 62.4% of them. The most frequent histological diagnosis was membranous glomerulonephritis (21.1%, followed by extracapillary glomerulonephritis (20.2%. When clinical syndromes and histological findings were compared, the nephrotic syndrome was found to be the main feature of membranous nephropathy (78.3%, of focal segmental glomerulosclerosis (55.6% and of diabetic nephropathy (66.7%. Kidney failure was present in 90% of the cases of extracapillary glomerulonephritis (95.5% pauciimmune or type 3. Microscopic hematuria was the main sign of mesangial prolifeative glomerulonephritis (83.3%. Conclusions: Nephrotic syndrome and kidney failure (especially rapidly progressive renal failure were the main renal biopsy results in this group of patients, bearing close relation to histological findings. The most common types of glomerulonephritis were membranous GN and pauciimmune extracapillary GN. Renal biopsy provides useful information for the diagnosis, prognosis and treatment of kidney disease in the elderly.

  5. Sepsis por shigella flexneri

    Directory of Open Access Journals (Sweden)

    César Cabrera C

    2005-04-01

    Full Text Available Se presenta un caso raro de sepsis por Shigella flexneri en una paciente de 45 años de edad quien estando hospitalizada para el estudio de un tumor cerebral, requirió el uso de manitol y dosis altas de corticoides; luego de ello presenta deposiciones líquidas con moco y sangre, desarrolla síndrome de respuesta inflamatoria sistémica, luego se aísla Shigella flexneri en el hemocultivo; recibió tratamiento antibiótico con ciprofloxacina. Se describen las características del caso y se comenta de acuerdo con la revisión de literatura.

  6. Ojo por ojo

    OpenAIRE

    del Llano Ibáñez, Ramón

    2011-01-01

    Nuestro pan y café de la mañana se acompaña de noticias alrededor de ejecuciones, de fosas clandestinas, de batallas del ejército, de balaceras en las calles y civiles caídos por balas perdidas : la muerte acompaña nuestro desayuno. Las calaveras de azúcar del día de muertos hoy son calaveras reales y amargas : 40 000 muertos en cuatro años después que el Presidente Calderón declaró la guerra a los narcotraficantes. Se han apresado a varios e importantes miembros de los cárteles : pero han si...

  7. Physical Activity and Renal Transplantation

    Directory of Open Access Journals (Sweden)

    Vincenzo Bellizzi

    2014-07-01

    Full Text Available Renal transplantation is burdened by high cardiovascular risk because of increased prevalence of traditional and disease-specific cardiovascular risk factors and, consequently, patients are affected by greater morbidity and mortality. In renal transplanted patients, healthy lifestyle and physical activity are recommended to improve overall morbidity and cardiovascular outcomes. According to METs (Metabolic Equivalent Task; i.e. the amount of energy consumed while sitting at rest, physical activities are classified as sedentary (<3.0 METs, of moderate-(3.0 to 5.9 METs or vigorous-intensity (≥6.0 METs. Guidelines suggest for patients with chronic kidney disease an amount of physical activity of at least 30 minutes of moderate-intensity activity five times per week (min 450 MET-minutes/week. Data on physical activity in renal transplanted patients, however, are limited and have been mainly obtained by mean of non-objective methods. Available data suggest that physical activity is low either at the start or during renal transplantation and this may be associated with poor patient and graft outcomes. Therefore, in renal transplanted patients more data on physical activity obtained with objective, accelerometer-based methods are needed. In the meanwhile, physical activity have to be considered as an essential part of the medical care for renal transplanted recipients.

  8. Puesta al día: estadificación del carcinoma de células renales Update on staging of renal cell carcinoma.

    Directory of Open Access Journals (Sweden)

    Lisandro Paganini

    2012-09-01

    Full Text Available El cáncer de células renales o adenocarcinoma renal es el tumor renal maligno más frecuente en adultos, con una incidencia mayor entre la cuarta y sexta décadas de la vida. Los hombres se afectan el doble que las mujeres. En Argentina, por año se calcula una incidencia de 6,1 casos por 100.000 habitantes, con una mortalidad anual de 3,4 casos por 100.000 habitantes. Para la estadificación se utiliza el sistema TNM de la American Joint Committee on Cancer (AJCC, actualizado en su séptima edición (2010. Allí se reflejan algunos cambios en el T, con subdivisión de la categoría T2 (T2a > 7 cm y 10 cm. Asimismo, se considera T4 a la invasión por contigüidad de la glándula suprarrenal homolateral y T3a al compromiso de la vena renal. También se simplificó el N en N0 y N1.Renal cell cancer or renal adenocarcinoma is the most common malignant renal tumor in adults, with a higher incidence between the fourth and sixth decades of life. It is twice more frequent in men than in women. In Argentina, the estimated incidence is 6.1 cases per 100000 inhabitants per year with a mortality rate of 3.4 cases per 100000 inhabitants per year. Staging is performed using the TNM system of the American Joint Committee on Cancer (AJCC, which has been updated in its seventh edition, (2010 reflecting changes in T, with T2 subdivision (T2a > 7 cm and 10 cm, reclassification of ipsilateral adrenal involvement as T4 if there is contiguous invasion and reclassification of renal vein involvement as T3a. Nodal involvement was simplified to N0 and N1.

  9. La prueba de la fenolsufonptaleina en la investigación de la función renal

    OpenAIRE

    Velásquez, Manuel A.; Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

    2014-01-01

    Continuando con el estudio de los métodos indirectos de apreciación de la función renal, métodos basados en la introducción en el organismo de sustancias que son eliminadas por el riñón, ya sea a nivel del glomérulo ya por un proceso secretorio de la célula renal, vamos a ocuparnos de la fenolsulfonptaleína, sustancia introducida por ROWNTREE y GEPAGHTY, para estudiar el funcionamiento del riñón, y que tiene la ventaja de ser inócua e inalterable por una parte, y ser totalmente eliminada por ...

  10. Portable exhausters POR-004 SKID B, POR-005 SKID C, POR-006 SKID D storage plan

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, O.D.

    1997-09-04

    This document provides a storage plan for portable exhausters POR-004 SKID B, POR-005 SKID C, AND POR-006 SKID D. The exhausters will be stored until they are needed by the TWRS (Tank Waste Remediation Systems) Saltwell Pumping Program. The storage plan provides criteria for portable exhauster storage, periodic inspections during storage, and retrieval from storage.

  11. Renal Heme Oxygenase-1 Induction with Hemin Augments Renal Hemodynamics, Renal Autoregulation, and Excretory Function

    Directory of Open Access Journals (Sweden)

    Fady T. Botros

    2012-01-01

    Full Text Available Heme oxygenases (HO-1; HO-2 catalyze conversion of heme to free iron, carbon monoxide, and biliverdin/bilirubin. To determine the effects of renal HO-1 induction on blood pressure and renal function, normal control rats (n=7 and hemin-treated rats (n=6 were studied. Renal clearance studies were performed on anesthetized rats to assess renal function; renal blood flow (RBF was measured using a transonic flow probe placed around the left renal artery. Hemin treatment significantly induced renal HO-1. Mean arterial pressure and heart rate were not different (115±5 mmHg versus 112±4 mmHg and 331±16 versus 346±10 bpm. However, RBF was significantly higher (9.1±0.8 versus 7.0±0.5 mL/min/g, P<0.05, and renal vascular resistance was significantly lower (13.0±0.9 versus 16.6±1.4 [mmHg/(mL/min/g], P<0.05. Likewise, glomerular filtration rate was significantly elevated (1.4±0.2 versus 1.0±0.1 mL/min/g, P<0.05, and urine flow and sodium excretion were also higher (18.9±3.9 versus 8.2±1.0 μL/min/g, P<0.05 and 1.9±0.6 versus 0.2±0.1 μmol/min/g, P<0.05, resp.. The plateau of the autoregulation relationship was elevated, and renal vascular responses to acute angiotensin II infusion were attenuated in hemin-treated rats reflecting the vasodilatory effect of HO-1 induction. We conclude that renal HO-1 induction augments renal function which may contribute to the antihypertensive effects of HO-1 induction observed in hypertension models.

  12. Renale Osteogystrophie - radiologische Diagnostik

    Directory of Open Access Journals (Sweden)

    Kainberger F

    2001-01-01

    Full Text Available Die renale Osteodystrophie (ROD kann definiert werden als die Summe morphologischer Knochenveränderungen infolge des gestörten Kalzium-Phosphat-Stoffwechsels bei chronischer Niereninsuffizienz. Speziell in Österreich mit einer im internationalen Vergleich hohen Rate an Nierentransplantationen ist das radiologische Vollbild dieser Erkrankung heute nur mehr in seltenen Fällen zu sehen. Grundsätzliches Ziel der bildgebenden Diagnostik ist nicht so sehr die Primärdiagnose, sondern die gezielte Planung von Prophylaxe oder Therapie klinisch relevanter Komponenten. Als bildgebende Verfahren stehen neben konventionell-radiologischen Aufnahmetechniken die Osteodensitometrie und, zum Nachweis von Veränderungen der Nebenschilddrüsen, die Sonographie sowie die Szintigraphie zur Verfügung. Es werden vier empirisch abgeleitete radiologische Bildmuster, basierend auf den wichtigsten zugrundeliegenden Stoffwechselkomponenten, beschrieben: die malazische, die hyperparathyreote, die porotische und die hyperphosphatämische Form. Die Ziele der bildgebenden Untersuchung sind heute sowohl auf eine qualitative, als vor allem auch auf eine quantitative Diagnostik ausgerichtet.

  13. Renal failure in patients with multiple myeloma.

    Science.gov (United States)

    Almueilo, Samir H

    2015-01-01

    Renal dysfunction is encountered in 20-25% of patients with multiple myeloma (MM) at the time of diagnosis. There is often a precipitating event. Several biochemical and clinical correlations with renal failure in MM have been reported. Renal failure in MM is associated with worse outcome of the disease. We retrospectively analyzed the medical records of 64 patients with MM admitted to our institution during the period January 1992 to December 2012. Abnormal renal function was observed in 24 (37.5%) patients and 17 (26.6%) of them had renal failure; 14 of the 17 (82.4%) of patients with renal failure had Stage III MM. Urine Bence- Jones protein was positive in ten (58.8%) patients with renal failure versus ten (21.3%) patients without renal failure (P = 0.004). Potential precipitating factors of renal failure were determined in nine patients. Renal function normalized in 11 patients with simple measures, while six patients required hemodialysis; one remained dialysis dependent till time of death. Early mortality occurred in five (29.4%) patients with renal failure as compared with two (4.3%) patients in the group without renal failure (P = 0.005). In conclusion, renal failure is associated with a higher tumor burden and Bence-Jones proteinuria in patients with MM. It is reversible in the majority of patients; however, early mortality tends to be higher in patients with persistent renal failure.

  14. Control Multivariable por Desacoplo

    Directory of Open Access Journals (Sweden)

    Fernando Morilla

    2013-01-01

    Full Text Available Resumen: La interacción entre variables es una característica inherente de los procesos multivariables, que dificulta su operación y el diseño de sus sistemas de control. Bajo el paradigma de Control por desacoplo se agrupan un conjunto de metodologías, que tradicionalmente han estado orientadas a eliminar o reducir la interacción, y que recientemente algunos investigadores han reorientado con objetivos de solucionar un problema tan complejo como es el control multivariable. Parte del material descrito en este artículo es bien conocido en el campo del control de procesos, pero la mayor parte de él son resultados de varios años de investigación de los autores en los que han primado la generalización del problema, la búsqueda de soluciones de fácil implementación y la combinación de bloques elementales de control PID. Esta conjunción de intereses provoca que no siempre se pueda conseguir un desacoplo perfecto, pero que sí se pueda conseguir una considerable reducción de la interacción en el nivel básico de la pirámide de control, en beneficio de otros sistemas de control que ocupan niveles jerárquicos superiores. El artículo resume todos los aspectos básicos del Control por desacoplo y su aplicación a dos procesos representativos: una planta experimental de cuatro tanques acoplados y un modelo 4×4 de un sistema experimental de calefacción, ventilación y aire acondicionado. Abstract: The interaction between variables is inherent in multivariable processes and this fact may complicate their operation and control system design. Under the paradigm of decoupling control, several methodologies that traditionally have been addressed to cancel or reduce the interactions are gathered. Recently, this approach has been reoriented by several researchers with the aim to solve such a complex problem as the multivariable control. Parts of the material in this work are well known in the process control field; however, most of them are

  15. Paniculite criptocócica em transplantado renal Cryptococcal panniculitis in a renal transplant recipient

    Directory of Open Access Journals (Sweden)

    Beatriz M. Trope

    2008-06-01

    Full Text Available Os autores relatam um caso de paniculite criptocócica em paciente transplantado renal inicialmente tratado como celulite bacteriana. O diagnóstico definitivo só foi possível pela impressão clínica dermatológica confirmada pelo exame micológico. O tratamento foi realizado a princípio com anfotericina B e posteriormente com fluconazol, considerando-se as interações das drogas imunossupressoras utilizadas para evitar rejeição. A regressão clínica foi alcançada no sexto mês de tratamento, que, no entanto, foi mantido por 12 meses. São feitas considerações a respeito dessa forma rara de criptococose cutânea em transplantado de órgão sólido e suas implicações diagnósticas e terapêuticas.The authors report a case of cryptococcal panniculitis in a renal transplant recipient,which was initially mistaken for bacterial cellulitis. Dermatological evaluation and laboratory studies led to the definitive diagnosis. Treatment was started with amphotericin B, followed by oral fluconazol, taking into consideration their interactions with the immunossupressive drugs. Even though clinical improvement was attained after six months, treatment was maintained during a whole year. We discuss this rare presentation of cutaneous cryptococcosis in a solid organ transplant recipient, as well as its diagnosis and therapy.

  16. Bacteremias por bacilos gram-negativos

    Directory of Open Access Journals (Sweden)

    Adrelírio J. R. Gonçalves

    1969-01-01

    Full Text Available São apresentados 31 casos de bacteremia por gram-negativos, assunto que vem merecendo muita atenção dos pesquisadores nos últimos anos. Os organismos etiológicos mais importantes que apareceram em igualdade de freqüência foram Escherichia coli e Klebsiella-Aerobacter, sendo responsáveis por 58% do total das infecções, seguidos por Pseudomonas. A porta de entrada mais freqüente foi o trato urinário em 61,3% dos casos. A infecção foi mais comum no sexo masculino e a faixa etária de 50 a 60 anos predominou. O uso prévio de antibióticos foi um fator predisponente muito importante, seguido pelo uso de esteróides e citostáticos. As principais doenças predisponentes foram diabetes mellitus e neoplasias malignas. Os principais fatores precipitantes foram a manipulação do aparelho urinário, com infecção prévia ou desencadeada, cirurgia do aparelho digestivo, uronatia obstrutiva e obstrução biliar. As principais manifestações clínicas foram a presença de febre, calafrios e hipotensão arterial. A complicação mais freqüente foi o choque bacteriano que incidiu em 58% dos casos, aproximadamente três vêzes aquela relatada na literatura. As outras foram a insuficiência renal aguda, superinfecção e infecção pulmonar metastática. Considerações terapêuticas gerais e esquemas de antibióticos são propostos para estes casos. A mortalidade da bacteremia simples foi de 30,7% e quando associada ao choque elevou-se para 72,2% . As infecções por Pseudomonas foram 100% fatais.

  17. Renal infarction secondary to ketamine abuse.

    Science.gov (United States)

    Chen, Chin-Li; Chen, Jin-Li; Cha, Tai-Lung; Wu, Sheng-Tang; Tang, Shou-Hung; Tsao, Chih-Wei; Meng, En

    2013-07-01

    Renal infarction is an uncommon condition that resulted from inadequate perfusion of the kidney and is easily missed diagnosed due to its nonspecific clinical presentations. Major risk factors for renal infarction are atrial fibrillation, previous embolism, and ischemic and valvular heart disease. Progressive decrease in renal function or even death can occur if renal infarction is not diagnosed accurately and promptly. Ketamine abuse may cause variable urinary tract injury. However, renal infarction caused by ketamine abuse has never been reported. To our knowledge, this is the first documented case of renal infarction following nasal insufflation of ketamine.

  18. Compromiso renal en pacientes HIV+ Renal abnormalities in HIV infected patients

    Directory of Open Access Journals (Sweden)

    María Marta Pernasetti

    2010-06-01

    Full Text Available Varias complicaciones nefrológicas pueden ocurrir durante la infección por el virus de la inmunodeficiencia humana (HIV especialmente en estadios avanzados de la enfermedad o relacionadas con otras infecciones o drogas. Poco conocida es la prevalencia de alteraciones renales subclínicas de pacientes HIV+ surgidas como complicación o relacionadas a la infección y/o tratamiento. Realizamos un corte transversal de pacientes asintomáticos HIV+ referidos en forma consecutiva al consultorio de nefrología para la detección de alteraciones nefrológicas. Se estudiaron 52 pacientes adultos mediante exámenes de sangre y orina, ultrasonido y biopsia renal. Edad media 39.9 ± 10.6 años, 88% varones, tiempo de diagnóstico de la infección: 53.2 ± 41.2 (2-127 meses. El 71% tenían síndrome de inmunodeficiencia adquirida (HIV-sida y el 77% recibían con antirretrovirales. La carga viral al momento del estudio fue 7043 ± 3322 copias y el recuento de CD4+ 484 ± 39 cel/mm³. El 30.7% presentó alteraciones del sedimento urinario: albuminuria: 16.6%, hematuria microscópica: 11.5%, hipercalciuria: 10.8% y cristaluria 6%. La media del filtrado glomerular fue 102.2 ± 22.9 ml/min (rango: 34-149. El 41% presentó anormalidades que corresponderían a enfermedad renal crónica (estadios 1 a 3. Los pacientes con alteraciones tenían mayor edad, con duración más prolongada de la infección. Las anomalías renales no se asociaron con mayor prevalencia de HIV-sida. Dos pacientes fueron biopsiados, con hallazgos de nefritis túbulo-intersticial crónica con cristales y glomerulonefritis por IgA. No hubo hallazgos de nefropatía por HIV. El amplio espectro y la alta prevalencia de anormalidades nefrológicas subclínicas encontradas sugieren que los pacientes asintomáticos HIV+ deberían realizar evaluaciones nefrológicas de rutina.Several renal complications may occur during HIV infection, especially in advanced stages related to HIV, to other infectious

  19. Sociedad por Acciones Simplificada

    Directory of Open Access Journals (Sweden)

    Carlos Andrés Arcila Salazar

    2009-06-01

    Full Text Available En Colombia, aspectos como la responsabilidad limitada; supresión de la llamada doctrina de ultra vires; duración ilimitada; eliminación de la regla, una acción, un voto; remedios al abuso de los derechos; posibilidad de eliminar prohibiciones a los administradores, libertad de establecer restricciones para la transferencia de acciones y la simplificación de los procedimientos de fusión; son inviables bajo nuestra legislación. Sin embargo, la Ley 1258 de 2008, ha incorporado al derecho societario colombiano un nuevo tipo societario híbrido, llamado “Sociedad por Acciones Simplificada”. Esta forma societaria híbrida se basa en un principio básico: garantizar amplia libertad a los empresarios en la estructuración de sus relaciones a través de disposiciones contractuales. La S.A.S. provee a los empresarios significativa flexibilidad contractual, a la vez que preserva beneficios como la limitación de la responsabilidad.

  20. Sociedad por Acciones Simplificada

    Directory of Open Access Journals (Sweden)

    Carlos Andrés Arcila Salazar

    2009-07-01

    Full Text Available En Colombia, aspectos como la responsabilidad limitada; supresión de la llamada doctrina de ultra vires; duración ilimitada; eliminación de la regla, una acción, un voto; remedios al abuso de los derechos; posibilidad de eliminar prohibiciones a los administradores, libertad de establecer restricciones para la transferencia de acciones y la simplificación de los procedimientos de fusión; son inviables bajo nuestra legislación. Sin embargo, la Ley 1258 de 2008, ha incorporado al derecho societario colombiano un nuevo tipo societario híbrido, llamado “Sociedad por Acciones Simplificada”. Esta forma societaria híbrida se basa en un principio básico: garantizar amplia libertad a los empresarios en la estructuración de sus relaciones a través de disposiciones contractuales. La S.A.S. provee a los empresarios significativa flexibilidad contractual, a la vez que preserva beneficios como la limitación de la responsabilidad.

  1. Trasplante renal en bloque de donantes pediátricos

    Directory of Open Access Journals (Sweden)

    Pedro Méndez-Chacón

    2005-03-01

    Full Text Available Objetivo: Determinar la aceptación de ambos riñones de donantes pediátricos para utilizarlos como trasplante renal en bloque. Material y Métodos: La edad de los seis donantes varió entre 14 meses y 10 años. La causa de muerte fue el traumatismo encefalocraneano. La edad de los seis receptores osciló entre 15 y 48 años con peso menor de 50 kg. Ambos riñones fueron removidos en bloque. La técnica operatoria de los trasplantes consistió en la anastomosis término lateral del segmento aórtico y vena cava inferior del donante a los vasos ilíacos del receptor; ambos uréteres fueron anastomosados por separado a la vejiga. El implante fue localizado en una de las fosas ilíacas. Resultados: Los injertos en bloque funcionaron inmediatamente. Cuatro de los seis receptores cursaron con función renal adecuada a cuatro años promedio de seguimiento. Uno de los injertos en bloque se perdió por rechazo vascular severo y otro por indisciplina a la medicación inmunosupresora. Las series ecográficas de los riñones revelaron incremento de tamaño hasta en 55% de su dimensión original al tercer mes del trasplante. Conclusión: Se recomienda que los riñones procedentes de donantes menores de tres años de edad sean utilizados como trasplante en bloque y riñones de donantes mayores de tres años como trasplante renal simple. Se demuestra que es posible trasplantar exitosamente riñones en bloque de niños muy pequeños en receptores mayores, según experiencia inédita en nuestro medio.

  2. Renal replacement therapy choices for pre-dialysis renal patients.

    Science.gov (United States)

    Tweed, Alison E; Ceaser, Karen

    With the numbers of patients developing end-stage renal failure predicted to increase over the coming years, more patients than ever will be expected to choose their future form of renal replacement treatment. This study explored the decision-making processes of pre-dialysis patients to elucidate how these choices were made. Nine pre-dialysis patients were interviewed, transcripts of which were analysed using interpretative phenomenological analysis. Four main themes relating to the decision-making process emerged: maintaining one's integrity, forced adaptation, utilizing information, and support and experiencing illness. While making a decision was an individualized process, contextualized within participants' illness experiences, these core themes emerged for the whole group, irrespective of the chosen treatment modality. For renal services, there is a need to tailor information provided to pre-dialysis patients and to become cognizant of the contexts in which they live and operate.

  3. Scintigraphy of renal transplant; Exploration scintigraphique du greffon renal

    Energy Technology Data Exchange (ETDEWEB)

    Ramackers, J.M.; Marrast, A.C.; Touraine, J.L.; Peyrin, J.O. [Hopital Edouard-Herriot, 69 - Lyon (France)

    1995-12-31

    Scintigraphy is useful for monitoring perfusion and function of renal transplant, as well as for diagnosing miscellaneous surgical. This non-invasive imaging technique, which uses no deleterious products, is an attractive alternative for patients. This is especially true for those patients in early post-transplant course, with immunity depression and often impairment of renal function. Otherwise, multiple indices with a large range of inter-patient values has not favoured a methodological and interpretative consensus. Furthermore, the poor specificity of renogram patterns does not allow for discrimination of all etiologies with only one scintigraphy. Nevertheless, follow-up with iterative scintigraphy may be helpful due to the high intra-patient reproducibility and to the early appreciate change of parameters, according to clinical and histological renal post-transplant outcome. (authors). 43 refs., 8 figs.

  4. Renal hemodynamics after lung transplantation : A prospective study

    NARCIS (Netherlands)

    Navis, Ger Jan; Broekroelofs, J.; Mannes, G.P M; van der Bij, W.; de Boer, W.J.; Tegzess, Adam; de Jong, Paul

    1996-01-01

    Renal function impairment is common after solid organ transplantation, due to the nephrotoxicity of cyclosporine, Moreover, in patients with severe respiratory failure, renal function is often impaired, This renal function impairment may predispose patients to further renal function impairment after

  5. Radiological diagnosis of renal oncocytoma

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Shoichi; Hayashi, Yutaro; Tsugaya, Masayuki; Okamura, Takehiko; Sakakura, Takeshi; Kohri, Kenjiro [Nagoya City Univ. (Japan). Medical School

    1995-09-01

    Eight patients (nine tumors) with histologically proven renal oncocytoma are presented. In all cases, differential diagnosis between renal oncocytoma and renal cell carcinoma could not be done on ultrasonography. On selective renal angiography, extended arteries surrounding the tumor margin was demonstrated in six of seven tumors without a spoke-wheel arterial supply. A sharp and smooth margin with capsule (lucent rim) could be found in five cases, and a spoke-wheel configuration of vessels could be seen in only two cases. A spoke-wheel pattern might be found with tumor growth. All tumors on computed tomography (CT scan) have a distinct margin, a smooth contour and a homogeneous appearance on contrast enhanced CT scan. The capsule and the presence of a central scar were clearly seen on T{sub 1} and T{sub 2} weighted images of magnetic resonance imaging (MRI). It is helpful to differentiate the oncocytoma from renal cell carcinoma. The modality of MRI may be useful in the preoperative diagnosis of oncocytoma. (author).

  6. Biochemical Markers of Renal Function.

    Science.gov (United States)

    Krstic, Danijela; Tomic, Nenad; Radosavljevic, Branimir; Avramovic, Natasa; Dragutinovic, Vesna; Skodric, Sanja Radojevic; Colovic, Mirjana

    2016-01-01

    Kidney damage can be induced by ischemia, autoimmune diseases, hypertension, allograft rejection, metabolic or genetic disorders, infections or toxins. The influence of these factors could result in acute kidney injury (AKI) defined as an unexpected decrease in urine output or renal function, or encourage the development of chronic kidney disease (CKD). Biomarkers of renal function, measured in urine and serum, are in increasing use in order to estimate the severity and nature of kidney injury, and consequently apply appropriate therapy and improve patient management. The determined values of biomarkers can suggest the potential risk of kidney disease and the type of renal injury, predict the disease progression, as well as be helpful for assessing the response to an applied therapy. Although novel biomarkers are in practical use, serum creatinine, the indicator of glomerular filtration rate is still the most frequently used biomarker of renal function despite its known limitations. In recent decades, numerous studies resulted in discovering urinary and serum proteins that can serve as biomarkers for early and accurate detection of AKI and its development, as well as the identification of CKD. This review gives an overview of the most important renal biomarkers investigated in kidney diseases, classified in following types: functional biomarkers, up-regulated proteins, enzymes, and cycle arrest biomarkers. It describes their properties, physiological roles, and discusses the utility of these molecules in different clinical settings.

  7. Gastrointestinal complications in renal transplantation

    Directory of Open Access Journals (Sweden)

    Kamal Jeet Singh

    2004-01-01

    Full Text Available Objective: Gastrointestinal complications are responsible for substantial morbidity and mortality among renal allograft recipients. We retrospectively analyzed incidence of these complications and their impact on the patient outcome. Materials & Methods: Between 1998 to Aug 2002, 558 live related renal transplants were performed at our center. The immunosuppression used consisted mainly of cyclosporine, azathioprine and prednisolone, though varied in some patients. These patients were followed for any occurrence of significant gastrointestinal problems. Results: Out of the of 538 renal transplant recipients studied, gastro esophageal ulcerations were seen in 3% patients. Acute pancreatitis was observed in twelve (2.2% patients and four patients had acute intestinal obstruction secondary to fecal impaction. Infectious complications included acute diarrheas in 18% of patients. Three patients developed abdominal tuberculosis. Acute rejection episodes were encountered in 26% of the patients. During these episodes, 58% of patients experienced prolonged ileus. Most of these complications (66% occurred within first one-year post transplant. Three patients presenting with acute intestinal obstruction required laparotomy (two- bands, one-intussusception. There were four mortalities -two patients had severe pancreatitis, one patient had massive upper GI bleed and one succumbed due to perforation peritonitis. Conclusions: Gastrointestinal complications account for significant morbidity and mortality in renal transplant recipients. Paralytic ileus secondary to acute vascular rejection is quite common and resolves spontaneously with recovery of renal function.

  8. Extracellular Vesicles in Renal Pathophysiology.

    Science.gov (United States)

    Pomatto, Margherita A C; Gai, Chiara; Bussolati, Benedetta; Camussi, Giovanni

    2017-01-01

    Extracellular vesicles are a heterogeneous population of microparticles released by virtually all living cells which have been recently widely investigated in different biological fields. They are typically composed of two primary types (exosomes and microvesicles) and are recently commanding increasing attention as mediators of cellular signaling. Indeed, these vesicles can affect recipient cells by carrying and delivering complex cargos of biomolecules (including proteins, lipids and nucleic acids), protected from enzymatic degradation in the environment. Their importance has been demonstrated in the pathophysiology of several organs, in particular in kidney, where different cell types secrete extracellular vesicles that mediate their communication with downstream urinary tract cells. Over the past few years, evidence has been shown that vesicles participate in kidney development and normal physiology. Moreover, EVs are widely demonstrated to be implicated in cellular signaling during renal regenerative and pathological processes. Although many EV mechanisms are still poorly understood, in particular in kidney, the discovery of their role could help to shed light on renal biological processes which are so far elusive. Lastly, extracellular vesicles secreted by renal cells gather in urine, thus becoming a great resource for disease or recovery markers and a promising non-invasive diagnostic instrument for renal disease. In the present review, we discuss the most recent findings on the role of extracellular vesicles in renal physiopathology and their potential implication in diagnosis and therapy.

  9. Idosos com insuficiência renal crônica: alterações do estado de saúde

    OpenAIRE

    Kusumota,Luciana; Rodrigues,Rosalina Aparecida Partezani; Marques, Sueli

    2004-01-01

    Descrever as alterações do estado de saúde vivenciadas por idosos portadores de Insuficiência Renal Crônica (IRC), em tratamento de Diálise Peritonial Contínua Ambulatorial (DPCA), atendidos na Unidade de Diálise e Transplante Renal de um Hospital Público de Ribeirão Preto-SP foi o objetivo deste estudo. Participaram seis idosos, com idade entre 61 e 74 anos, em tratamento com DPCA. O referencial teórico metodológico utilizado foi a história oral temática, proposta por Meihy. Na análise, foi ...

  10. Componente hiperplásico del crecimiento compensatorio renal temprano

    OpenAIRE

    Domínguez Magadán, P. A.; Blanco, M.D.; Rodríguez, E.; Colaneri, Y.; Fernández Blanco, Ayelén; Errecalde, Ana Lía; García, Adriana L.

    2013-01-01

    La remoción de un riñón estimula inmediatamente el crecimiento y la función del otro; no obstante hay diferentes mecanismos que inician este crecimiento compensatorio renal (CCR), dependiendo en parte, de la edad y del sexo. Por ejemplo, en animales adultos la nefrectomía induce un crecimiento, principalmente, de tipo hipertrófico. Sin embargo, en trabajos previos nosotros observamos que en ratones adultos de ambos sexos, a las 26 horas de la nefrectomía (Nx), hay un aumento en la actividad m...

  11. Renal function during calcitriol therapy in chronic renal failure.

    Science.gov (United States)

    Bertoli, M; Luisetto, G; Ruffatti, A; Urso, M; Romagnoli, G

    1990-02-01

    Some authors have reported that vitamin D treatment worsens renal function. We studied 10 patients with stable renal function, who were given calcitriol (0.5 micrograms/day) for a 4-month period. Creatinine and inulin clearance were performed at the beginning and at the end of the treatment. Although serum creatinine increased and creatinine clearance decreased, inulin clearance did not show significant variations. Furthermore, serum creatinine fell to the baseline value within 60 days after discontinuation of vitamin D therapy. The increased serum creatinine may be explained by an augmented release from muscular tissue, probably due to the improvement of uremic myopathy induced by calcitriol.

  12. Sobre el conocimiento por connaturalidad

    OpenAIRE

    Buzeta-Undurraga, S. (Sebastián)

    2013-01-01

    El conocimiento por connaturalidad es un tópico central en la filosofía y teología de Tomás de Aquino, no tanto por la cantidad de páginas que dedicó a su estudio, sino por su naturaleza y radicalidad para la vida humana; pues se trata de un conocimiento integral, es decir, se funda desde una armonía de todas las facultades para que el entendimiento humano juzgue verdaderamente, conforme a su naturaleza, desde su naturaleza. No consiste en un tipo de conocimiento por el perfecto uso de la fac...

  13. HOSPITALIZACIONES EVITABLES POR INSUFICIENCIA CARDÍACA. VARIABLES RELACIONADAS

    Directory of Open Access Journals (Sweden)

    Victoria Ruiz-Romero

    2016-01-01

    Full Text Available Los ingresos hospitalarios evitables por insuficiencia cardiaca (IC son un problema para los sistemas de salud, consumen recursos, generan morbilidades adicionales y alta mortalidad. El objetivo del estudio fue conocer los factores de riesgo de las personas hospitalizadas por insuficiencia cardiaca. Métodos: Se constituyó un grupo con médicos de atención primaria y hospitalaria. Se realizaron auditorías de las historias clínicas de 110 pacien - tes de la poblacion de la comarca del Aljarafe con mayores tasas de ingreso por insuficiencia cardiaca y estudio descriptivo y comparativo con T-Student y U-Mann Whitney para cuantitativas y λ 2 y Fisher para cualitativas. Resultados: Los pacientes que ingresaron por IC tenían 78,1 años (SD: 9,56 de media; 73 (66,4% fueron mujeres; un Índice Barthel de 45,0 de media; un 53,5% con grado III de la NYHA y 17 (15,5% institucionaliza - dos. El 70% presentaban 3-5 comorbilidades, hipertensión (87,3%, dislipe - mia (60,0% diabetes (57,3%, enfermedad renal crónica (56,4%, anemia (53,2% o fibrilación auricular (52,7%. Fallecieron al ingreso 23 (20,9% pacientes. Conclusiones: Los ingresos se dieron en personas mayores con múl - tiples enfermedades (hipertensión, diabetes, EPOC, enfermedad renal y escasa capacidad para actividades básicas de la vida diaria. El fallecimiento hospitalario se asoció a edad avanzada, ser mujer, menor uso de betabloqueantes y la no inclusión del paciente en el proceso asistencial.

  14. Lúpus eritematoso sistêmico e tuberculose renal: descrição de nove Casos Systemic lupus erythematosus and renal tuberculosis: description of nine cases

    Directory of Open Access Journals (Sweden)

    Daniela Cabral de Sousa

    2008-02-01

    Full Text Available OBJETIVO: O presente estudo tem por objetivo principal descrever uma série de nove casos de tuberculose (TB renal em pacientes portadores de lúpus eritematoso sistêmico (LES ocorridos em um período de seis anos em um hospital terciário do Nordeste brasileiro. MÉTODOS: Foram identificados nove pacientes portadoras de LES com baciloscopia e/ou cultura de urina positivas para Mycobacterium tuberculosis no período de outubro de 1998 a novembro de 2004, por intermédio dos registros do Serviço de Microbiologia do Hospital Universitário Walter Cantídio. Foram coletados dados demográficos, dados sobre o LES e sobre a TB renal das respectivas pacientes. RESULTADOS: Todas as pacientes eram do sexo feminino, com idade entre 19 e 58 anos. Quanto às características do LES, todas haviam tido nefrite lúpica em algum momento da evolução, das quais três haviam utilizado ciclofosfamida previamente à infecção. A dose média de prednisona antes do diagnóstico de TB renal variou entre 7, 5 e 20 mg/dia. O diagnóstico de TB renal foi feito por meio de cultura positiva em cinco pacientes e por intermédio de baciloscopia apenas em quatro pacientes. As manifestações laboratoriais mais freqüentes foram leucocitúria e hematúria. A recidiva da TB renal ocorreu em quatro pacientes. CONCLUSÃO: A ocorrência de TB renal em pacientes com LES deve ser suspeitada na presença de piúria estéril e/ou hematúria persistentes, em especial em populações de países em desenvolvimento.OBJECTIVE: The main objective of the present study was to describe a series of nine cases of renal tuberculosis (TB in patients diagnosed with systemic lupus erythematosus (SLE over a period of six years at a tertiary-level hospital in Northeastern Brazil. METHODS: Nine SLE patients with renal TB confirmed by bacterioscopy (n=4 or urine culture (n=5 positive for M. tuberculosis between October 1998 and November 2004 were sampled from the records of the microbiology

  15. Renal Myxoma, an Incidental Finding

    Directory of Open Access Journals (Sweden)

    Parth Thakker

    2017-07-01

    Full Text Available Myxomas are mesenchymal tumors commonly found in the heart and skin. Renal myxomas are rare, having only been documented 14 times. Our case is a 55-year-old woman who presented to our clinic after a right renal mass was incidentally found on CT. Evaluation with MRI showed a mass that appeared to arise from the supero-medial cortex of the right kidney. As the imaging was concerning for renal cell carcinoma, the patient underwent a partial nephrectomy. Microscopic examination showed a well-circumscribed mass with polygonal to spindle-shaped cells in a granular eosinophilic cytoplasm. Immunohistochemical staining for CD-10, Desmin, HMB-45, and Pankeratin were negative.

  16. Pseudoporphyria secondary to renal failure

    Directory of Open Access Journals (Sweden)

    Lilianna Kulczycka-Siennicka

    2017-04-01

    Full Text Available Introduction . Pseudoporphyria is a rare disease associated with chronic renal failure. Symptoms of pseudoporphyria may develop in response to UV exposure and medications. The literature reports cases of pseudoporphyria in patients infected with hepatis C virus, HIV and undergoing dialysis therapy. Objective . Presentation of the case of a patient with pseudoporphyria and uraemic pruritus, and overview of therapeutic management. Case report . A 64-year-old male patient, who had been on dialysis for chronic renal failure secondary to type 2 diabetes for the past 11 years, presented with tense bullae located on sun-exposed skin which had persisted for the previous 5 months. The patient was diagnosed with pseudoporphyria, and treatment was prescribed including N-acetylcysteine, chloroquine, paroxetine and mianserin. An improvement in the patient’s clinical condition and a regression of pruritus were achieved. Conclusions . Patients with renal failure may develop symptoms of pseudoporphyria requiring differentiation from porphyria cutanea tarda.

  17. Parasites and chronic renal failure.

    Science.gov (United States)

    Mohammadi Manesh, Reza; Hosseini Safa, Ahmad; Sharafi, Seyedeh Maryam; Jafari, Rasool; Bahadoran, Mehran; Yousefi, Morteza; Nasri, Hamid; Yousofi Darani, Hossein

    2014-01-01

    Suppression of the human immune system results in an increase in susceptibility to infection by various infectious agents. Conditions such as AIDS, organ transplantation and chronic renal insufficiency (CRI) are the most important cause of insufficient immune response against infections. Long term renal disorders result in uremia, which can suppress human immune system. Parasitic infections are one of the most important factors indicating the public health problems of the societies. These infections can be more hostile and life threatening in susceptible individuals than in the normal people. In these patients some parasitic infections such as blastocystiosis, cryptosporidiosis and toxoplasmosis have been reported to be more prevalent. This review aimed to give an overview about parasitic infections in patients with renal disorders.

  18. The renal arterial resistive index and stage of chronic kidney disease in patients with renal allograft

    DEFF Research Database (Denmark)

    Winther, Stine O; Thiesson, Helle C; Poulsen, Lene N

    2012-01-01

    The study investigated the optimal threshold value of renal arterial resistive index as assessed by Doppler ultrasonography determining chronic kidney disease stage 4 or higher in patients with renal allograft.......The study investigated the optimal threshold value of renal arterial resistive index as assessed by Doppler ultrasonography determining chronic kidney disease stage 4 or higher in patients with renal allograft....

  19. Renal involvement in Down syndrome.

    Science.gov (United States)

    Málaga, Serafín; Pardo, Rafael; Málaga, Ignacio; Orejas, Gonzalo; Fernández-Toral, Joaquín

    2005-05-01

    Kidney disease has not been considered a frequent complication in Down syndrome (DS) patients; a variety of urological abnormalities and glomerulopathies have been reported in this population, and some DS patients develop chronic renal failure (CRF). The aim of this study was to improve the understanding of renal disease in patients with DS, focusing on the incidence and range of kidney and urological abnormalities in a population of DS patients. A cross-sectional study was carried out in DS patients referred from a pediatric genetics unit of a tertiary care center. Medical records were reviewed. A 24-h urine specimen and a blood sample were obtained. Fractional excretion of sodium and potassium, tubular reabsorption of phosphate, urinary excretion of calcium, magnesium, uric acid, creatinine clearance and proteinuria were determined. Ultrasound was performed to evaluate the kidneys and the urinary tract. Laboratory data were reviewed for any possible renal disorder. Sixty-nine patients, aged 12 months to 24 years, were recruited. Pathological findings included three cases of voiding disturbances and a case of hypertension in a 7-year old girl. Eight patients (11.6%) had hyperuricemia without gout. Eighteen patients (24.2%) had hyperuricosuria. Urinalysis revealed three cases of mild proteinuria and two patients with microscopic hematuria. Minor radiological abnormalities were found in five patients (7.3%). Three patients (4.5%) had CRF. Renal disease in patients with DS is not as rare as previously thought, although the majority of findings are of minor relevance. According to the variety of pathologies, and in order to detect early irreversible renal injury, it seems quite reasonable to perform regular monitoring of renal function in these patients.

  20. Renal consequences of preterm birth.

    Science.gov (United States)

    Stritzke, Amelie; Thomas, Sumesh; Amin, Harish; Fusch, Christoph; Lodha, Abhay

    2017-12-01

    The developmental origin of health and disease concept identifies the brain, cardiovascular, liver, and kidney systems as targets of fetal adverse programming with adult consequences. As the limits of viability in premature infants have been pushed to lower gestational ages, the long-term impact of prematurity on kidneys still remains a significant burden during hospital stay and beyond. The purpose of this study is to summarize available evidence, mechanisms, and short- and long-term renal consequences of prematurity and identify nephroprotective strategies and areas of uncertainty. Kidney size and nephron number are known to be reduced in surviving premature infants due to disruption of organogenesis at a crucial developmental time point. Inflammation, hyperoxia, and antiangiogenic factors play a role in epigenetic conditioning with potential life-long consequences. Additional kidney injury from hypoperfusion and nephrotoxicity results in structural and functional changes over time which are often unnoticed. Nephropathy of prematurity and acute kidney injury confound glomerular and tubular maturation of preterm kidneys. Kidney protective strategies may ameliorate growth failure and suboptimal neurodevelopmental outcomes in the short term. In later life, subclinical chronic renal disease may progress, even in asymptomatic survivors. Awareness of renal implications of therapeutic interventions and renal conservation efforts may lead to a variety of short and long-term benefits. Adequate monitoring and supplementation of microelement losses, gathering improved data on renal handling, and exploration of new avenues such as reliable markers of injury and new therapeutic strategies in contemporary populations, as well as long-term follow-up of renal function, is warranted.

  1. Intoxicación ocupacional por mercurio

    Directory of Open Access Journals (Sweden)

    Augusto V Ramírez

    2008-03-01

    Full Text Available El mercurio, metal pesado ampliamente utilizado por el hombre, es muy tóxico; produce daño al sistema nervioso central, perturbaciones del comportamiento y lesiones renales. Se acumula en todos los seres vivos y no es esencial para ningún proceso biológico. La toxicidad del mercurio está directamente relacionada con su estado químico. El metilmercurio es la forma más dañina, con efectos neurotóxicos en adultos y en fetos de madres expuestas. El mercurio metálico no es menos tóxico. Las sales de mercurio inorgánico afectan directamente al riñón. Clínicamente, en la exposición ocupacional a mercurio se encuentra la triada clásica: temblor, alteración de la personalidad y estomatitis. En los últimos años se ha demostrado también alteración en la visión cromática. La exposición aguda se evalúa midiendo el mercurio en la sangre, mientras que la exposición crónica y ocupacional se determina mejor dosándolo en orina homogenizada de 24 horas. Los quelantes del metal -BAL, sus derivados o la D-penicilamina- son usados para tratar la intoxicación aguda o crónica.

  2. Renal-sparing strategies in cardiac transplantation

    DEFF Research Database (Denmark)

    Gustafsson, Finn; Ross, Heather J

    2009-01-01

    reduction in terms of preserving renal function. Patients with longstanding CNI treatment or proteinuria are less likely to respond favourably to a switch from a CNI-based regimen to a proliferation signal inhibitor-based regimen. SUMMARY: Each cardiac transplant recipient with renal dysfunction must...... be individually evaluated with respect to degree of renal dysfunction, proteinuria and rejection risk and a renal sparing strategy chosen accordingly....

  3. Prevention Of Chronic Renal Diseases

    OpenAIRE

    Fejzi Alushi; Nestor Thereska

    2011-01-01

    It is easier to prevent a disease than to cure it. This postulate is a foundation stone of the contemporary medicine, furthermore its mission. The Chronic Kidney Diseases (CKD), amongst them the Chronic Pyelonephrites (CP) and the mass kidney reduction  take an important  place in human pathologies in general, and in particular in renal ones. The Chronic Pyelonephrites  are chronic renal pathologies, which on one side are of various causes and on the other side are multi systemic. At the same...

  4. Impaired renal allograft function is associated with increased arterial stiffness in renal transplant recipients

    DEFF Research Database (Denmark)

    Kneifel, M; Scholze, A; Burkert, A

    2006-01-01

    It is important whether impairment of renal allograft function may deteriorate arterial stiffness in renal transplant recipients. In a cross-sectional study, arterial vascular characteristics were non-invasively determined in 48 patients with renal allograft using applanation tonometry and digital...... of large arteries S1 and small arteries S2 in renal transplant recipients (each p renal allograft (p ...-Wallis test between groups). It is concluded that impairment of renal allograft function is associated with an increased arterial stiffness in renal transplant recipients....

  5. Displasia renal multiquística: manejo conservador Multicystic renal dysplasia: conservative management

    Directory of Open Access Journals (Sweden)

    Sandalio Durán Álvarez

    2004-12-01

    Full Text Available Durante el período comprendido entre enero 1 de 1996 y diciembre 31 de 2003, fueron recibidos en la consulta de Nefrología del Hospital Pediátrico Docente "William Soler", 120 niños, nacidos en ese período, y a quienes se les había detectado, mediante ultrasonido materno-fetal, anomalías o alteraciones del tracto urinario. Siete de estos niños fueron diagnosticados como displasia renal multiquística (DRMQ, 4 por el estudio prenatal y 3 que se interpretaron como hidronefrosis severa y, después del nacimiento se pudo establecer el diagnóstico de la displasia. Todos los niños pertenecen al sexo masculino, 6 tenían la forma clásica (hidronefrótica de displasia renal multiquística izquierda y 1 tenía una displasia multiquística sólida del lado derecho. A todos los pacientes se les realizó estudio gammagráfico renal, en 4 estático y en 3 dinámico, por haberse planteado la posibilidad de hidronefrosis. En todos los casos se siguió una conducta conservadora con control ultrasonográfico periódico. En 3 pacientes se comprobó involución total de los quistes a los 3, 5, y 72 meses de edad; en 2 una involución parcial a los 35 y 40 meses de edad y en 2 no hubo modificaciones del tamaño de los quistes entre los 9 y 24 meses de edad.From January 1 st , 1996 to December 31 st , 2003 , 120 children that were born during that period received attention at the nephrologist's office of “William Soler” Pediatric Teaching Hospital. Abnomalities or alterations of the urinary tract have been detected by maternofetal ultrasound. 7 of these children were diagnosed multicystic rernal displasia (MCRD, 4 by the prenatal study and 3 that were interpreted as severe hydronephrosis and after birth the diagnosis of displasia was confirmed. All the children were males, 6 had the classical form (hydronephrotic of left multicystic renal displasia and one had solid multicystic displasia of the right side. Renal scintigraphy was peformed in all

  6. Papillary adenocarcinoma of the renal pelvis with renal calculus: A rare case report

    Science.gov (United States)

    LI, JIANLONG; LI, QING; YU, YI

    2016-01-01

    Papillary adenocarcinoma of the renal pelvis is a rare clinicopathology of a kidney tumor with renal calculus. In the present case report, percutaneous renal biopsy, nephroscope lithotripsy and radical nephroureterectomy within a papillary adenocarcinoma of the renal pelvis accompanied with renal calculus was performed on a 65-year-old patient, also including a report on the patient's data and a literature review. The histopathological features confirmed the diagnosis of papillary adenocarcinoma of the renal pelvis. Tumors of the renal pelvis are uncommon features of urothelial carcinoma, and papillary adenocarcinoma of the renal pelvis is a very unusual entity. The present case report describes papillary adenocarcinoma of the renal pelvis with renal calculus, which has rarely been previously reported. PMID:27123287

  7. Insuficiencia renal crónica en pacientes con diabetes tipo 2

    National Research Council Canada - National Science Library

    Praga Terente, Manuel

    2010-01-01

    ... que la prevalencia de enfermedad renal crónica (ERC) estadio 3 (definida precisamente por un FG estimado inferior a 60 ml/min/1,73 m 2 ) era de un 7–10% en los sujetos de 60 a 69 años y superior al 25% en aquellos de más de 70 años. Dado que estos estudios se realizaron en población normal, sin antecedentes conocidos o clínica manifiesta de enfermedad renal...

  8. Factores de riesgo asociados al desarrollo de eventos cardiovasculares en pacientes postrasplante renal

    OpenAIRE

    Ana M. Barón; Ángel A. García-Peña; Paola K. García; Edna Salazar; Carlos Andrés Blanco; María C. Betancur; Nicolás F. Amaya

    2018-01-01

    Objetivo: describir el comportamiento de los factores de riesgo cardiovascular en pacientes con trasplante renal y su relación con los desenlaces cardiovasculares a uno y cinco años luego del trasplante. Métodos: se realizó un estudio analítico de cohorte retrospectivo en los pacientes con trasplante renal del Hospital Universitario San Ignacio con seguimiento institucional por lo menos de un año. Se analizaron las variables demográficas, los factores de riesgo cardiovascular y los desenla...

  9. Duplicidade da artéria renal em cão Renal artery duplicity in dog

    Directory of Open Access Journals (Sweden)

    Fabrício Singaretti de Oliveira

    2007-12-01

    Full Text Available Alterações vasculares renais são observadas com baixa freqüência em medicina veterinária e podem ter implicações diretas no funcionamento normal destes órgãos devido à alteração do fluxo sangüíneo. Assim, o objetivo deste relato é descrever um caso de duplicidade da artéria renal em uma cadela de cinco anos, sem raça definida e com 18kg. O animal veio a óbito após hemoparasitose crônica e foi submetido à injeção de látex pela aorta torácica, na altura do sexto espaço intercostal esquerdo. O animal foi dissecado após fixação com solução de formol a 10%, no laboratório de Anatomia Animal da Faculdade de Medicina Veterinária da UNICASTELO, Campus Fernandópolis, SP, visando-se à evidenciação dos ramos da aorta abdominal. Observou-se que o rim direito era irrigado por duas artérias, de calibres diferentes, caracterizando uma duplicidade dessa artéria renal. A artéria secundária apresentava diâmetro 28,1% menor que a principal do mesmo antímero e 34,3% menor que a principal do outro antímero. Ambas as artérias adentravam o rim pela região do hilo renal e apresentavam trajetos praticamente paralelos. O rim esquerdo apresentava irrigação pela artéria renal correspondente, sem qualquer alteração anatômica em número. Esta duplicidade da artéria renal deve ser considerada em cães, principalmente quando alterações renais estiverem presentes ou quando intervenções cirúrgicas abdominais forem conduzidas próxima aos rins, visando-se, dessa forma, a evitar que erros sejam cometidos por desconhecimento anatômico de estruturas importantes.Renal vessels abnormalities are noticed with low frequency in veterinary medicine ad may have direct implications on the regular functioning of these organs due blood flow change. Thus, the aim of this report is describe a case of duplicity of the renal artery in a five year crossbred female weighting 18kg. The animal went to death due chronic hemoparasitosis and had

  10. Renal oncocytoma in a cat with chronic renal failure

    Directory of Open Access Journals (Sweden)

    Sora Lee

    2017-02-01

    Full Text Available Case summary A 9-year-old male neutered domestic shorthair cat presented with anorexia. Ultrasonography showed an irregularly shaped hypoechoic mass in the cranial pole of the right kidney. Ultrasound-guided fine-needle aspiration of the renal mass was performed. Cytology revealed moderate cellularity smears composed of epithelial cell clusters, which consisted of an exclusive population of oncocytic cells seen in sheets and papillary clusters along with abundant single cells. A moderate-to-abundant amount of densely stained granular cytoplasm with round nuclei and indistinct nucleoli was seen. The cytological diagnosis was renal oncocytic neoplasm. CT and surgical resection revealed a firm tan mass in the right kidney. A final diagnosis of renal oncocytoma was made on the basis of histology, immunohistochemical staining profile (positive for cytokeratin, and negative for chromogranin A, neuron-specific enolase and vimentin of neoplastic cells, together with the electronic microscopy results. Relevance and novel information We believe that this is the first report of the cytological features of feline renal oncocytoma.

  11. [Disorders of hemostasis in chronic renal failure and renal transplantation].

    Science.gov (United States)

    Goluza, Eleonora; Topalović, Marija Grković; Hudolin, Tvrtko; Konosić, Sanja; Kocman, Iva Bacak; Perić, Mladen

    2011-01-01

    The presence of end-stage renal disease (ESRD) has been associated with profound clinical effects on hemostasis ranging from thrombosis to bleeding complications. The pathogenesis of uremic bleeding is multifactorial. It has been attributed to platelet dysfunction, the most important feature, particularly platelet-platelet and platelet-vessel wall interactions. Renal replacement therapy has helped reduce bleeding episodes, but the risk of morbidity and mortality due to hemorrhage persists. Abnormalities of blood coagulation and fibrinolysis predispose uremic patients to hypercoagulable state carrying the risk of atherosclerotic cardiovascular disease and thrombotic complications such as thrombosis of the vascular access wall. There are differences in the measurement of various hemostatic parameters in patients with ESRD concerning treatment with either hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD). Hemostatic disturbances are overlapped by changes in the coagulation/fibrinolytic system after renal transplantation (RT). Despite the etiology, renal transplant patients are at an increased risk of thromboembolic events as a consequence of prothrombotic clotting and fibrinolytic abnormalities. This hypercoagulable state is to a large extent associated with immunosuppressive drugs. This review will give a summary of views on hemostasis in patients with ESRD and after RT.

  12. Renal epithelioid angiomyolipoma presenting clinically as renal cell ...

    African Journals Online (AJOL)

    M.S. Johnson

    (AML) and its potentially malignant variant epithelioid angiomy- olipoma (EAML). PEComas are associated with the tuberous sclerosis complex and characterized by the World Health Organi- zation as a “proliferation of perivascular epithelioid cells (PECs)”. [1]. EAML is often confused with renal cell carcinoma (RCC) given.

  13. Relationship Between Adult Renal Dimensions and Biometric ...

    African Journals Online (AJOL)

    We measured renal dimensions sonographically and correlated the values obtained with some anthropometric parameters in order to identify the best estimate of renal size in a clinical setting. The renal dimensions of 200 adult subjects referred for abdomino-pelvic scan at University of Nigeria Teaching Hospital, Enugu ...

  14. Hypogonadism and renal failure: An update.

    Science.gov (United States)

    Thirumavalavan, Nannan; Wilken, Nathan A; Ramasamy, Ranjith

    2015-01-01

    The prevalence of both hypogonadism and renal failure is increasing. Hypogonadism in men with renal failure carries with it significant morbidity, including anemia and premature cardiovascular disease. It remains unclear whether testosterone therapy can affect the morbidity and mortality associated with renal failure. As such, in this review, we sought to evaluate the current literature addressing hypogonadism and testosterone replacement, specifically in men with renal failure. The articles chosen for this review were selected by performing a broad search using Pubmed, Embase and Scopus including the terms hypogonadism and renal failure from 1990 to the present. This review is based on both primary sources as well as review articles. Hypogonadism in renal failure has a multifactorial etiology, including co-morbid conditions such as diabetes, hypertension, old age and obesity. Renal failure can lead to decreased luteinizing hormone production and decreased prolactin clearance that could impair testosterone production. Given the increasing prevalence of hypogonadism and the potential morbidity associated with hypogonadism in men with renal failure, careful evaluation of serum testosterone would be valuable. Testosterone replacement therapy should be considered in men with symptomatic hypogonadism and renal failure, and may ameliorate some of the morbidity associated with renal failure. Patients with all stages of renal disease are at an increased risk of hypogonadism that could be associated with significant morbidity. Testosterone replacement therapy may reduce some of the morbidity of renal failure, although it carries risk.

  15. Molecular differential pathology of renal cell tumours.

    Science.gov (United States)

    Kovacs, G

    1993-01-01

    Recent application of molecular cytogenetic techniques to the evaluation of renal cell tumours revealed four subtypes, each with a characteristic combination of genetic alterations within the chromosomal and mitochondrial DNA. The most common, nonpapillary renal cell carcinomas are characterized by the loss of chromosome 3p sequences, rearrangement of the chromosome 5q region and loss of the chromosome 14q sequences. Papillary renal cell tumours can be divided into two groups. Tumours with a combined trisomy of chromosomes 7 and 17 as well as loss of the Y chromosome are papillary renal cell adenomas. Tumours with additional trisomies such as trisomy 16, 20 or 12 are papillary renal cell carcinomas. Chromophobe renal cell carcinomas show a combination of allelic losses, which do not occur in other types of renal tumours. In addition, they have a rearrangement in the mitochondrial DNA. Renal oncocytomas are benign tumours marked by normal or abnormal karyotypes with balanced or unbalanced translocations and an altered restriction pattern of the mitochondrial DNA. Although the major cytological characteristics of renal cell tumours, such as clear, granular, chromophobe and oncocytic cell phenotypes correspond to nonpapillary, papillary and chromophobe renal cell carcinomas and renal oncocytomas, there are many cases with overlapping phenotype. Therefore, a classification of renal cell tumours based on specific genetic alterations is proposed.

  16. Pseudocystic CT pattern of renal sinus lipomatosis

    Energy Technology Data Exchange (ETDEWEB)

    Downey, E.F. Jr.; Friedman, A.C.; Hartman, D.S.; Pyatt, R.S.; Thane, T.T.; Warnock, G.R.

    1982-09-01

    Previous reports of renal sinus lipomatosis (RSL) have emphasized the CT finding of increased fat around the renal pelvis. The authors present a case in which the CT density of the renal sinus was the same as water. This density appears to depend on the relative amounts of fat and fibrous tissue present.

  17. TRPV5 gene polymorphisms in renal hypercalciuria.

    NARCIS (Netherlands)

    Renkema, K.Y.; Lee, K.; Topala, C.N.; Goossens, M.; Houillier, P.; Bindels, R.J.M.; Hoenderop, J.G.J.

    2009-01-01

    BACKGROUND: Kidney stone formation is a major socioeconomic problem in humans, involving pain, recurrent treatment and renal insufficiency. As most renal precipitates contain calcium as a major component, hypercalciuria is the main risk factor for renal stone formation. Different forms of

  18. Primary Renal Carcinoid - A Case Report

    LENUS (Irish Health Repository)

    O’Sullivan, M

    2018-01-01

    Carcinoid tumours in the abdomen are uncommon, but typically occur in the gastrointestinal tract. Primary renal carcinoid is an extremely rare tumour, poorly described in the literature. We describe an unusual case where an atypical renal mass on imaging led to a preoperative diagnosis of renal carcinoid on imaging guiding biopsy.

  19. El recuerdo viaja por Italia

    Directory of Open Access Journals (Sweden)

    Néstor Madrid Malo

    1965-09-01

    Full Text Available Espero que mis lectores puedan acompañarme en este viaje del recuerdo por Italia, en esta travesía restrospectiva por el cuerpo duradero, por el dorso sustantivo - vertebrado dulcemente, ásperamente, por el vasto cinturón apenínico- de un país donde la vida tiene una manera tan suya de ser grata, de transcurrir en todo momento significativamente. Y donde cada instante, cada sitio, está signado de plenitudes inefables, de expresivos modos de mostrársenos e insinuársenos, hasta hacerse todos ellos, por siempre, memorables e insistentes habitantes de nuestros mejores sueños y vigilias.

  20. Trasplante renal en pacientes con anticuerpos dirigidos contra donante

    Directory of Open Access Journals (Sweden)

    Federico Cicora

    2014-10-01

    Full Text Available En trasplante renal, los anticuerpos donante-específicos por ensayos de fase sólida predicen el rechazo temprano mediado por anticuerpos, incluso con resultados negativos de citometría de flujo o citotoxicidad dependiente del complemento. Aquí se describen los protocolos de inmunosupresión y los resultados a diez meses de cuatro pacientes en los que se detectó anticuerpos donante-específicos anti-antígenos leucocitarios humanos (HLA por Luminex®, pero no detectados por el método de citotoxicidad dependiente de complemento (CDC ni por citometría de flujo. Los cuatro pacientes recibieron tratamiento de inducción con 5 dosis de timoglobulina de 1.25 mg/kg y 5 dosis de inmunoglobulina intravenosa (IVIG de 400 mg/kg. Además, uno recibió 20 mg de basiliximab el mismo día del trasplante y el día 4 postrasplante; otro recibió 3 sesiones de plasmaféresis en los días -5, -3, y -1 y eculizumab en dosis de 1200 mg antes del trasplante, 900 mg el día 1, and 600 mg por semana durante un mes. En todos los casos, la inmunosupresión de mantenimiento consistió en tacrolimus, micofenolato y deltisona. Todos presentaron buenos resultados en el corto plazo. Nuestra experiencia sugiere que los pacientes con anticuerpos donante-específicos anti-HLA detectados solo por Luminex® deben recibir un seguimiento estricto y que en esta población se pueden obtener buenos resultados a partir del uso de terapia de inducción con timoglobulina e IVIG.

  1. Automated renal histopathology: digital extraction and quantification of renal pathology

    Science.gov (United States)

    Sarder, Pinaki; Ginley, Brandon; Tomaszewski, John E.

    2016-03-01

    The branch of pathology concerned with excess blood serum proteins being excreted in the urine pays particular attention to the glomerulus, a small intertwined bunch of capillaries located at the beginning of the nephron. Normal glomeruli allow moderate amount of blood proteins to be filtered; proteinuric glomeruli allow large amount of blood proteins to be filtered. Diagnosis of proteinuric diseases requires time intensive manual examination of the structural compartments of the glomerulus from renal biopsies. Pathological examination includes cellularity of individual compartments, Bowman's and luminal space segmentation, cellular morphology, glomerular volume, capillary morphology, and more. Long examination times may lead to increased diagnosis time and/or lead to reduced precision of the diagnostic process. Automatic quantification holds strong potential to reduce renal diagnostic time. We have developed a computational pipeline capable of automatically segmenting relevant features from renal biopsies. Our method first segments glomerular compartments from renal biopsies by isolating regions with high nuclear density. Gabor texture segmentation is used to accurately define glomerular boundaries. Bowman's and luminal spaces are segmented using morphological operators. Nuclei structures are segmented using color deconvolution, morphological processing, and bottleneck detection. Average computation time of feature extraction for a typical biopsy, comprising of ~12 glomeruli, is ˜69 s using an Intel(R) Core(TM) i7-4790 CPU, and is ~65X faster than manual processing. Using images from rat renal tissue samples, automatic glomerular structural feature estimation was reproducibly demonstrated for 15 biopsy images, which contained 148 individual glomeruli images. The proposed method holds immense potential to enhance information available while making clinical diagnoses.

  2. Chemical Renal Denervation in the Rat

    Energy Technology Data Exchange (ETDEWEB)

    Consigny, Paul M., E-mail: paul.consigny@av.abbott.com; Davalian, Dariush, E-mail: dariush.davalian@av.abbott.com [Abbott Vascular, Innovation Incubator (United States); Donn, Rosy, E-mail: rosy.donn@av.abbott.com; Hu, Jie, E-mail: jie.hu@av.abbott.com [Abbott Vascular, Bioanalytical and Material Characterization (United States); Rieser, Matthew, E-mail: matthew.j.rieser@abbvie.com; Stolarik, DeAnne, E-mail: deanne.f.stolarik@abbvie.com [Abbvie, Analytical Pharmacology (United States)

    2013-12-03

    Introduction: The recent success of renal denervation in lowering blood pressure in drug-resistant hypertensive patients has stimulated interest in developing novel approaches to renal denervation including local drug/chemical delivery. The purpose of this study was to develop a rat model in which depletion of renal norepinephrine (NE) could be used to determine the efficacy of renal denervation after the delivery of a chemical to the periadventitial space of the renal artery. Methods: Renal denervation was performed on a single renal artery of 90 rats (n = 6 rats/group). The first study determined the time course of renal denervation after surgical stripping of a renal artery plus the topical application of phenol in alcohol. The second study determined the efficacy of periadventitial delivery of hypertonic saline, guanethidine, and salicylic acid. The final study determined the dose–response relationship for paclitaxel. In all studies, renal NE content was determined by liquid chromatography–mass spectrometry. Results: Renal NE was depleted 3 and 7 days after surgical denervation. Renal NE was also depleted by periadventitial delivery of all agents tested (hypertonic saline, salicylic acid, guanethidine, and paclitaxel). A dose response was observed after the application of 150 μL of 10{sup −5} M through 10{sup −2} M paclitaxel. Conclusion: We developed a rat model in which depletion of renal NE was used to determine the efficacy of renal denervation after perivascular renal artery drug/chemical delivery. We validated this model by demonstrating the efficacy of the neurotoxic agents hypertonic saline, salicylic acid, and guanethidine and increasing doses of paclitaxel.

  3. Guidelines on renal cell cancer

    NARCIS (Netherlands)

    Mickisch, G; Carballido, J; Hellsten, S; Schuize, H; Mensink, H

    Objectives., On behalf of the European Association of Urology (EAU), Guidelines for Diagnosis, Therapy and. Follow Up of Renal. Cell Carcinoma Patients were established. Criteria for recommendations were evidence based and included aspects of cost-effectiveness and clinical feasibility. Method: A

  4. Interventional treatment of renal angiomyolipoma

    DEFF Research Database (Denmark)

    Andersen, Poul Erik; Thorlund, Mie Gaedt; Egge Wennevik, Gjertrud

    2015-01-01

    BACKGROUND: Renal angiomyolipoma is rare, but many of these patients may have an acute debut with severe bleeding. These patients need urgent treatment with interventional embolization as an attractive option. PURPOSE: To investigate the technical and clinical effect of this treatment and to eval......BACKGROUND: Renal angiomyolipoma is rare, but many of these patients may have an acute debut with severe bleeding. These patients need urgent treatment with interventional embolization as an attractive option. PURPOSE: To investigate the technical and clinical effect of this treatment....... RESULTS: The renal angiomyolipoma decreased significantly from mean 7.2 cm to 2.9 cm after embolization (p = 0.04). Cortical infarctions of about one-third of the circumference of the embolized kidneys could be detected on follow-up examinations, but all patients had normal total kidney function...... patient had a nephrectomy one month after embolization because of infection and re-bleeding and one patient after 2.5 years because of tumor size >4 cm. The technical success was 7/8 (88%) and clinical success was 6/8 patients (75%). CONCLUSION: Selective embolization of renal angiomyolipoma...

  5. MRI Phenotype in Renal Cancer

    Science.gov (United States)

    Campbell, Naomi; Rosenkrantz, Andrew B.; Pedrosa, Ivan

    2015-01-01

    Renal cell carcinoma (RCC) is most commonly diagnosed as an incidental finding on cross-sectional imaging and represents a significant clinical challenge. Although most patients have a surgically curable lesion at the time of diagnosis, the variability in the biologic behavior of the different histologic subtypes and tumor grade of RCC, together with the increasing array of management options, creates uncertainty for the optimal clinical approach to individual patients. State-of-the-art magnetic resonance imaging (MRI) provides a comprehensive assessment of renal lesions that includes multiple forms of tissue contrast as well as functional parameters, which in turn provides information that helps to address this dilemma. In this article, we review this evolving and increasingly comprehensive role of MRI in the detection, characterization, perioperative evaluation, and assessment of the treatment response of renal neoplasms. We emphasize the ability of the imaging “phenotype” of renal masses on MRI to help predict the histologic subtype, grade, and clinical behavior of RCC. PMID:24690616

  6. Renal Protective Effects of Resveratrol

    Directory of Open Access Journals (Sweden)

    Munehiro Kitada

    2013-01-01

    Full Text Available Resveratrol (3,5,4′-trihydroxystilbene, a natural polyphenolic compound found in grapes and red wine, is reported to have beneficial effects on cardiovascular diseases, including renal diseases. These beneficial effects are thought to be due to this compound’s antioxidative properties: resveratrol is known to be a robust scavenger of reactive oxygen species (ROS. In addition to scavenging ROS, resveratrol may have numerous protective effects against age-related disorders, including renal diseases, through the activation of SIRT1. SIRT1, an NAD+-dependent deacetylase, was identified as one of the molecules through which calorie restriction extends the lifespan or delays age-related diseases, and this protein may regulate multiple cellular functions, including apoptosis, mitochondrial biogenesis, inflammation, glucose/lipid metabolism, autophagy, and adaptations to cellular stress, through the deacetylation of target proteins. Previous reports have shown that resveratrol can ameliorate several types of renal injury, such as diabetic nephropathy, drug-induced injury, aldosterone-induced injury, ischemia-reperfusion injury, sepsis-related injury, and unilateral ureteral obstruction, in animal models through its antioxidant effect or SIRT1 activation. Therefore, resveratrol may be a useful supplemental treatment for preventing renal injury.

  7. Novel genes in renal aging

    NARCIS (Netherlands)

    Noordmans, Gerda Anke

    2015-01-01

    Renal aging is characterized by structural changes and functional decline. These changes make the elderly more vulnerable to chronic kidney disease, hypertension, and cardiovascular disease. Furthermore, they also make it more difficult to cope with stress factors, such as dehydration, toxicity, and

  8. Angiopoietins in renal replacement therapy

    NARCIS (Netherlands)

    Westendorp, Welmoet Hillegonda

    2015-01-01

    The aim of this thesis is to elucidate the role of the Ang/Tie2-system before, during and after dialysis and renal transplantation. It came of interest since endothelial dysfunction plays a considerable role in these conditions. Therefore, we investigated angiopoietin levels in hemodialysis patients

  9. Extracellular vesicles in renal disease.

    Science.gov (United States)

    Karpman, Diana; Ståhl, Anne-Lie; Arvidsson, Ida

    2017-09-01

    Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages of information that allow cell-cell communication and enable cells to rid themselves of unwanted substances. The release and uptake of extracellular vesicles has important physiological functions and may also contribute to the development and propagation of inflammatory, vascular, malignant, infectious and neurodegenerative diseases. This Review describes the different types of extracellular vesicles, how they are detected and the mechanisms by which they communicate with cells and transfer information. We also describe their physiological functions in cellular interactions, such as in thrombosis, immune modulation, cell proliferation, tissue regeneration and matrix modulation, with an emphasis on renal processes. We discuss how the detection of extracellular vesicles could be utilized as biomarkers of renal disease and how they might contribute to disease processes in the kidney, such as in acute kidney injury, chronic kidney disease, renal transplantation, thrombotic microangiopathies, vasculitides, IgA nephropathy, nephrotic syndrome, urinary tract infection, cystic kidney disease and tubulopathies. Finally, we consider how the release or uptake of extracellular vesicles can be blocked, as well as the associated benefits and risks, and how extracellular vesicles might be used to treat renal diseases by delivering therapeutics to specific cells.

  10. Nefropatía no amiloidea por depósito de inmunoglobulinas monoclonales A propósito de un caso de enfermedad idiopática por depósito de cadenas ligeras

    Directory of Open Access Journals (Sweden)

    Jorge de Jesús Cantillo

    2009-12-01

    Se describen las características clínicas e histológicas del primer caso informado en Colombia de nefropatía por depósito de cadenas ligeras, diagnosticado en el contexto de una enfermedad renal paraproteinémica sin datos de malignidad.

  11. Captopril-induced acute renal artery thrombosis and persistent anuria in a patient with documented pre-existing renal artery stenosis and renal failure.

    Science.gov (United States)

    Williams, P. S.; Hendy, M. S.; Ackrill, P.

    1984-01-01

    We describe an elderly man, with pre-existing renal failure and atheromatous renal artery stenosis, who developed persistent anuria due to renal artery thrombosis after acute hypotension following captopril administration. Caution should be used when captopril is first administered to patients with impaired renal function in whom renal artery stenosis is known or suspected. Images Fig. 1 PMID:6382225

  12. Nefropatia Induzida por Contraste: Medidas de Prevenção

    OpenAIRE

    Caroline Kaercher Kramer; Cristiane Bauermann Leitão; Luís Henrique Canani; Jorge Luiz Gross; Sandra Pinho Silveiro

    2008-01-01

    A nefropatia do contraste é definida como piora na função renal que se segue à administração de contraste intravenoso, tendo sido excluídas outras causas. A nefropatia do contraste manifesta-se, usualmente, como uma insuficiência renal aguda não oligúrica. Por definição, deve haver um aumento na creatinina basal de 25-50% ou um aumento superior a 0,5 mg/dl em 24-48 horas após o uso intravenoso de contraste, na ausência de outras causas de piora da função renal. As medidas de prevenção são bas...

  13. Renal lesions of nondomestic felids.

    Science.gov (United States)

    Newkirk, K M; Newman, S J; White, L A; Rohrbach, B W; Ramsay, E C

    2011-05-01

    To comprehensively evaluate the occurrence of renal lesions in a variety of nondomestic felids, necropsy cases from 1978 to 2008 were reviewed from a municipal zoo and a large cat sanctuary for those in which the kidneys were examined histologically. Seventy exotic felids were identified (25 tigers, 18 lions, 6 cougars, 5 leopards, 3 snow leopards, 3 clouded leopards, 3 Canadian lynx, 2 ocelots, 2 bobcats, 2 cheetahs, 1 jaguar), and their histologic renal lesions were evaluated and compared. The most common lesion was tubulointerstitial nephritis (TIN); 36 of 70 (51%) cats were affected to some degree. Lymphocytic interstitial nephritis was the most common lesion in the tigers (9 of 25, 36%) and was rarely seen in other species. Although the renal pelvis was not available for all cats, 28 of 47 (60%) had some degree of lymphocytic pyelitis. There was no significant association between the presence of pyelitis and that of TIN. Only 1 cat had pyelonephritis. Renal papillary necrosis was present in 13 of 70 (19%) cats and was significantly associated with historical nonsteroidal anti-inflammatory drug treatment (odds ratio, 7.1; 95% confidence interval, 1.9 to 26.8). Only 1 cat (lion) had amyloid accumulation, and it was restricted to the corticomedullary junction. Primary glomerular lesions were absent in all cats. Intraepithelial pigment was identified in many of the cats but was not correlated with severity of TIN. Despite several previous reports describing primary glomerular disease or renal amyloidosis in exotic felids, these lesions were rare to absent in this population.

  14. Metastatic renal cell carcinoma management

    Directory of Open Access Journals (Sweden)

    Flavio L. Heldwein

    2009-06-01

    Full Text Available PURPOSE: To assess the current treatment of metastatic renal cell carcinoma, focusing on medical treatment options. MATERIAL AND METHODS: The most important recent publications have been selected after a literature search employing PubMed using the search terms: advanced and metastatic renal cell carcinoma, anti-angiogenesis drugs and systemic therapy; also significant meeting abstracts were consulted. RESULTS: Progress in understanding the molecular basis of renal cell carcinoma, especially related to genetics and angiogenesis, has been achieved mainly through of the study of von Hippel-Lindau disease. A great variety of active agents have been developed and tested in metastatic renal cell carcinoma (mRCC patients. New specific molecular therapies in metastatic disease are discussed. Sunitinib, Sorafenib and Bevacizumab increase the progression-free survival when compared to therapy with cytokines. Temsirolimus increases overall survival in high-risk patients. Growth factors and regulatory enzymes, such as carbonic anhydrase IX may be targets for future therapies. CONCLUSIONS: A broader knowledge of clear cell carcinoma molecular biology has permitted the beginning of a new era in mRCC therapy. Benefits of these novel agents in terms of progression-free and overall survival have been observed in patients with mRCC, and, in many cases, have become the standard of care. Sunitinib is now considered the new reference first-line treatment for mRCC. Despite all the progress in recent years, complete responses are still very rare. Currently, many important issues regarding the use of these agents in the management of metastatic renal cancer still need to be properly addressed.

  15. Chronic renal failure in children.

    Science.gov (United States)

    Hari, Pankaj; Singla, Ish Kumar; Mantan, Mukta; Kanitkar, Madhuri; Batra, Bobby; Bagga, Arvind

    2003-11-01

    To determine the etiology of chronic renal failure amongst children attending the Pediatric Nephrology services at a tertiary care center. We reviewed the records of 305 children, diagnosed to have chronic renal failure (CRF) over a 7-year period. CRF was defined as glomerular filtration rate (GFR) below 50-mL/1.73 m2/min persisting for more than 3 months. The mean age at onset and presentation of CRF in these patients was 5.9 and 8 years respectively. Ninety-six children were below 5 years of age. Mean (SD) levels of blood urea and creatinine at presentation were 150 and 4.6 mg/dL respectively. The median GFR at presentation was 18.5 mL/min/1.73 m(2) while 25.3 patients were already in end stage renal failure indicating that these patients were referred late. The mean (SD) hemoglobin at presentation was 7.6 (2.6) g/dL. The mean height and weight SD scores were 2.9 and 2.4 respectively. Obstructive uropathy was the commonest cause of CRF present in 97 children. Other causes included chronic glomerulonephritis in 84, reflux nephropathy in 51, hereditary nephritis in 20, renal dysplasia in 15 and hemolytic uremic syndrome in 5 children. The mean (SD) duration of follow-up was 11(15) months. Peritoneal or hemodialysis was performed in 63 patients. Fifteen patients underwent a live-related renal transplantation. The rest opted out of dialysis program and were conservatively managed due to financial constraints. The commonest causes of CRF were obstructive and reflux nephropathy. A significant proportion of patients presented late; had severe CRF and were malnourished and stunted. Majority of these were managed conservatively due to lack of financial resources.

  16. Uremic Hemolitic Syndrome induced by Escherichia Coli producer of Shiga toxin in a pediatric patient with renal transplant

    Directory of Open Access Journals (Sweden)

    Ana Paula Ramírez

    2017-04-01

    Full Text Available El Síndrome Urémico Hemolítico (SUH secundario a la infección por Escherichia coli productora de toxina Shiga (STEC serotipo O157:H7 es una enfermedad endémica en Argentina según la Organización Panamericana de la Salud, siendo en nuestro país, y en los niños la primera causa de Injuria renal aguda (IRA y la segunda causa de Insuficiencia Renal Crónica (IRC. Esta entidad clínica y anátomo-patológica se caracteriza por presentación aguda de daño renal, anemia hemolítica microangiopática y trombocitopenia, que puede afectar otros parénquimas como intestino, sistema nervioso central, páncreas, corazón e hígado. Más del 90% de los pacientes afectados se recuperan en período agudo, aunque se han descrito secuelas renales a largo plazo hasta en el 25% de ellos. Según nuestro conocimiento aún no ha sido descrito en nuestro país casos de síndrome urémico hemolítico secundario a infección por Escherichia coli, productora de STEC luego del Trasplante Renal (TxR.

  17. Neumonía necrosante por Staphylococcus aureus extrahospitalario resistente a la meticilina:reporte de dos casos en Colombia

    Directory of Open Access Journals (Sweden)

    Ana María Perilla

    2009-12-01

    Ambos desarrollaron falla renal aguda, por lo que fueron manejados con linezolide, con adecuada respuesta clínica. Con la caracterización molecular de los aislamientos se confirmó la presencia del gen mecA que porta el casete SCCmec tipo IV y la producción de la toxina leucocidina Panton-Valentine.

  18. Responsabilidade civil por abandono afetivo

    OpenAIRE

    Fidélis, Maria de Lourdes

    2013-01-01

    Este estudo tem por objetivo a análise da responsabilidade civil por abandono afetivo na relação paterno-filial a partir de recentes decisões dos tribunais brasileiros. Inicialmente discorre sobre a evolução da família contemporânea. Examina os elementos da responsabilidade civil objetivando uma interseção entre o novo Direito de Família e as transformações no dever de indenizar. A partir de dois casos paradigmáticos escolhidos busca-se encontrar os fundamentos e finalidades das demandas por ...

  19. Tratamento endovascular da estenose da artéria renal em rim único Endovascular treatment of renal stenosis in solitary kidney

    Directory of Open Access Journals (Sweden)

    Ana Terezinha Guillaumon

    2008-06-01

    Full Text Available CONTEXTO: O tratamento endovascular da doença renal hipertensiva, em doentes com rim único, conseqüente à estenose de artéria renal, mostrou ser efetivo na prevenção da falência do órgão, sua função e controle da hipertensão. Quando indicado após avaliação criteriosa, tanto bioquímica como por imagens e sinais do doente, o tratamento endovascular apresenta benefícios clínicos de forma efetiva e pouco invasiva. OBJETIVO: Estudar a doença hipertensiva renovascular e avaliar a eficácia do tratamento endovascular no controle da hipertensão arterial sistêmica e da insuficiência renal secundárias à estenose da artéria renal e como medida de prevenção de falência renal em doentes com rim único funcionante. MÉTODO: Estudo realizado com protocolo de atendimento previamente elaborado, no Centro de Referência de Alta Complexidade em Cirurgia Endovascular do Hospital de Clínicas da Universidade de Campinas, de abril de 1997 a junho de 2005, em 10 doentes com diagnóstico de estenose da artéria renal em rim único funcionante, submetidos ao tratamento endovascular. Foi avaliada a melhora da hipertensão e função renal através de seguimento clínico e laboratorial com medidas de pressão arterial, dosagens séricas de uréia, creatinina e clearance. Exames pelo eco-color-Doppler foram realizados no pós-operatório de 30 dias, 3 meses, 6 meses e anualmente; no caso de haver alguma dúvida na obtenção de imagens ou sinais, foi realizada a aortografia e arteriografia seletiva renal. Nesta casuística, 90% dos doentes apresentavam hipertensão arterial, 70% eram tabagistas, 40%, hiperlipidêmicos, 30% apresentavam doença oclusiva cerebral extracraniana, 60%, obstrução arterial crônica nos membros inferiores, e 20%, diabetes melito. RESULTADOS: O sucesso inicial foi de 100%. O seguimento médio foi de 40 meses. Houve controle da pressão arterial em 90%, diminuição significativa dos níveis de uréia e creatinina ap

  20. Microwave treatment of renal cell carcinoma adjacent to renal sinus

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Yongyan, E-mail: gaoyongyan7@163.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China); Department of Ultrasound, The General Hospital of Chinese People’s Armed Police Forces, 69 Yongding Road, Beijing, 100039 (China); Liang, Ping, E-mail: liangping301@hotmail.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China); Yu, Xiaoling, E-mail: 784107477@qq.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China); Yu, Jie, E-mail: 1411495161@qq.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China); Cheng, Zhigang, E-mail: 13691367317@163.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China); Han, Zhiyu, E-mail: hanzhiyu122@163.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China); Duan, Shaobo, E-mail: Dustin2662@163.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China); Huang, Hui, E-mail: 309hh@sina.com [Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853 (China)

    2016-11-15

    Highlights: • This study shows US-guided microwave ablation appears to be a promising method to treat renal cell carcinoma adjacent to renal sinus. • The estimated 1-, 3- and 5-year RCC-related survival were 100%, 93.3% and 93.3%, respectively. • The estimated 1-, 3- and 5-year overall survival were 97.1%, 87.8%, 83.6%, respectively. • For patients with RCC ≤4 cm, initial ablation success was 100% (29/29) and the estimated 5-year disease-free survival were 81.5%. - Abstract: Purpose: To evaluate the efficacy and safety of ultrasound (US)-guided percutaneous microwave ablation (MWA) for renal cell carcinoma (RCC) adjacent to renal sinus. Materials and methods: This retrospective study included 41 patients who underwent US-guided percutaneous MWA of 41 RCCs adjacent to the renal sinus from April 2006 to December 2015. Contrast-enhanced images of US and computed tomography (CT) or magnetic resonance (MR) imaging were performed at pre-ablation and 1 day, 1 month, 3 months, and every 6 months after ablation. Initial ablation success (IAS), disease-free survival (DFS), RCC-related survival (RRS), and overall survival (OS) were recorded at the follow-up visits. Results: IAS was achieved in 92.7% (38/41) of the study subjects. The IAS significantly differed between patients with RCCs ≤4 cm (100%, 29/29) and RCCs >4 cm (75%, 9/12, p = 0.021). During the median follow-up of 37.6 (range, 3.0–97.3) months, the estimated 1-, 3-, and 5-year DFS of patients with an initial tumor of ≤4 cm were 100%, 89.7%, and 81.5%, respectively. The 1-, 3-, and 5-year RRS were 100%, 93.3%, and 93.3%, respectively. The 1-, 3-, and 5-year OS were 97.1%, 87.8%, and 83.6%, respectively. The multivariate analysis using the Cox proportional hazard model revealed no independent predictor of recurrence among all the variables. There were no MWA-related deaths among the study subjects. One patient developed a retroperitoneal abscess after ablation. Conclusion: US-guided percutaneous MWA

  1. Bilateral multifocal renal oncocytoma in pregnancy

    Directory of Open Access Journals (Sweden)

    Schalk W. Wentzel

    2012-10-01

    Full Text Available Renal oncocytomas are the most common benign solid renal tumor, accounting for 3-7% of renal neoplasms. Oncocytomas are multifocal in 2-12% and bilateral in 4-14% of cases. Multifocal bilateral oncocytomas represent only 1.4% of renal cases. We present an extraordinary case of a patient with multifocal bilateral renal oncocytomas during pregnancy. An electronic literature search revealed fewer than 30 reports of on cases of bilateral multifocal renal oncocytomas, none of them occurring in pregnancy. The management of this patient differed from the recommended guidelines for renal masses suspected to be malignant because elective caesarean section and nephrectomy in the second trimester was refused.

  2. A case report: accessory right renal artery

    Directory of Open Access Journals (Sweden)

    Patasi B

    2009-10-01

    Full Text Available Anatomical variations in the origin of the arteries in the abdominal area are very common. The arteries that show frequent variations include the celiac trunk, renal and gonadal arteries. During a routine dissection of a male cadaver, one main and one inferior accessory renal artery were found in the abdominal region. We discovered that the inferior accessory renal artery that originated from the right anterolateral aspect of abdominal aorta was running into the lower pole of the right kidney. The origin of the main right renal artery and the inferior accessory right renal artery were 19.8 mm and 53 mm below the superior mesenteric artery, respectively. The inferior accessory right renal artery ran directly into the inferior pole of the right kidney, in the area where the accessory right renal vein was leaving the right kidney. These anatomical variations and anomalies are important to know before any therapeutic or diagnostic procedures are performed in the abdominal area.

  3. Evaluación de las concentraciones de aluminio en pacientes con terapia de reemplazo renal crónico con hemodiálisis en dos unidades renales en Bogotá, 2008

    OpenAIRE

    Cárdenas Bustamante, Omayda

    2010-01-01

    La exposición crónica a aluminio y la toxicidad relacionada con su absorción por medio de los fluidos de diálisis continúa siendo un problema para muchos pacientes con falla renal crónica, particularmente en países en desarrollo.

  4. Avaliação renal de hipertensos pela clearance de creatinina num centro de saúde de Teresina-PI, Brasil Evaluación renal de hipertensos en el aclaramiento de creatinina en un centro sanitario de Teresina- PI, Brasil Evaluation of renal hypertensive by creatinine clearance in a health center in Teresina-pi, Brazil

    Directory of Open Access Journals (Sweden)

    Dinah Sá Rezende Neta

    2012-03-01

    Full Text Available A Hipertensão Arterial Sistémica é uma das principais causas de Insuficiência Renal Crónica. Estudo de abordagem quantitativa, desenvolvido no Centro de Saúde Porto Alegre e que teve como objetivo avaliar a função renal de pacientes com hipertensão pela clearance de creatinina, a partir da mensuração da creatinina sérica. Foi realizado levantamento de dados a partir de consultas de enfermagem e solicitados exames de creatinina sérica. Após o cálculo da clearance de creatinina pela equação de Cockcroft-Gault classificou-se os pacientes em um dos seis estágios da Doença Renal Crónica. Os resultados evidenciaram que 74% da amostra apresentou lesão renal, o que mostra o quanto é importante a avaliação periódica da função renal dos pacientes com hipertensão para que possam ser acompanhados quanto a progressão da Doença Renal Crónica.Hipertensión Arterial Sistémica es una de las principales causas de Insuficiencia Renal Crónica. Por ello, este estudio tuvo por objetivo evaluar la función renal de los pacientes con hipertensión por medio del aclaramiento de creatinina, a partir de la medición de la creatinina sérica. Estudio de enfoque cuantitativo, elaborado en el Centro de Salud de Porto Alegre. La recolección de datos ocurrió en consultas de enfermería y fueron se solicitaron pruebas de la creatinina sérica. Tras realizar el cálculo del aclaramiento de la creatinina mediante la fórmula Cockcroft-Gault, los pacientes fueron clasificados en una de las seis etapas de la Enfermedad Renal Crónica. Los resultados revelaron que 74% de la muestra presentaron daño renal, lo cual demuestra cuán importante es la evaluación periódica de la función renal de los pacientes con hipertensión para que se les pueda controlada la progresión de la Enfermedad Renal Crónica.Systemic arterial hypertension is a leading cause of chronic renal failure. Thus, this study aimed at assessing the renal function of patients with

  5. Renal relevant radiology: renal functional magnetic resonance imaging.

    Science.gov (United States)

    Ebrahimi, Behzad; Textor, Stephen C; Lerman, Lilach O

    2014-02-01

    Because of its noninvasive nature and provision of quantitative measures of a wide variety of physiologic parameters, functional magnetic resonance imaging (MRI) shows great potential for research and clinical applications. Over the past decade, application of functional MRI extended beyond detection of cerebral activity, and techniques for abdominal functional MRI evolved. Assessment of renal perfusion, glomerular filtration, interstitial diffusion, and parenchymal oxygenation turned this modality into an essential research and potentially diagnostic tool. Variations in many renal physiologic markers can be detected using functional MRI before morphologic changes become evident in anatomic magnetic resonance images. Moreover, the framework of functional MRI opened a window of opportunity to develop novel pathophysiologic markers. This article reviews applications of some well validated functional MRI techniques, including perfusion, diffusion-weighted imaging, and blood oxygen level-dependent MRI, as well as some emerging new techniques such as magnetic resonance elastography, which might evolve into clinically useful tools.

  6. Renal replacement therapy in sepsis-induced acute renal failure

    Directory of Open Access Journals (Sweden)

    Rajapakse Senaka

    2009-01-01

    Full Text Available Acute renal failure (ARF is a common complication of sepsis and carries a high mortality. Renal replacement therapy (RRT during the acute stage is the mainstay of therapy. Va-rious modalities of RRT are available. Continuous RRT using convective methods are preferred in sepsis-induced ARF, especially in hemodynamically unstable patients, although clear evidence of benefit over intermittent hemodialysis is still not available. Peritoneal dialysis is clearly inferior, and is not recommended. Early initiation of RRT is probably advantageous, although the optimal timing of dialysis is yet unknown. Higher doses of RRT are more likely to be beneficial. Use of bio-compatible membranes and bicarbonate buffer in the dialysate are preferred. Anticoagulation during dialysis must be carefully adjusted and monitored.

  7. Colecistitis aguda por Streptococcus constellatus

    OpenAIRE

    M Sandra Gómez-Canosa; Cristina Lijó-Carballeda; Begoña Vázquez-Vázquez; M José Bello-Peón

    2016-01-01

    Presentamos el caso de una paciente de edad avanzada y significativa comorbilidad que se diagnosticó de colecistitis aguda por Streptococcus constellatus. El drenaje de la vesícula biliar por colecistostomía percutánea, asociado a penicilinas, ha conseguido una evolución favorable. We report the case of a patient of advanced age and significant comorbidity diagnosed acute cholecystitis by Streptococcus constellatus. Gallbladder drainage by percutaneous cholecystostomy associated ...

  8. Porøse materialer

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2000-01-01

    Dette undervisningsnotat er en samling af noter, der refererer til den indledende del af kurset Materialmekanik og Porøse materailer på Insitut for Bærende Konstruktiner og Materialer (BKM).......Dette undervisningsnotat er en samling af noter, der refererer til den indledende del af kurset Materialmekanik og Porøse materailer på Insitut for Bærende Konstruktiner og Materialer (BKM)....

  9. Otitis externa por Demodex cati

    OpenAIRE

    Real, L.

    2010-01-01

    La demodicosis por Demodex cati es una enfermedad parasitaria poco común que se presenta bajo tres formas clínicas: generalizada, localizada y otitis externa ceruminosa u otodemodicosis. El objetivo de esta comunicación es presentar dos casos clínicos de otitis ceruminosa causada por D.cati sin la presencia de otros síntomas cutáneos.

  10. Biomarcadores de daño renal temprano asociados al consumo de tabaco

    OpenAIRE

    Sanz Parras, Francisco José

    2016-01-01

    [ES] El tabaco es un factor de riesgo (FR) asociado a la progresión de patologías como el cáncer, las enfermedades pulmonares y las enfermedades cardiovasculares. En las últimas décadas se ha observado un incremento del daño renal en individuos fumadores con patologías como la diabetes, la hipertensión, la enfermedad renal crónica. Sin embargo, existe poca evidencia de la asociación entre el consumo de tabaco y la producción de daño renal en individuos sanos. Por otra parte, el diagnóstico de...

  11. ENFERMEDAD CARDIOVASCULAR (ECV EN LA ENFERMEDAD RENAL CRÓNICA (ERC

    Directory of Open Access Journals (Sweden)

    Dr. Rodrigo Orozco B.

    2015-03-01

    Full Text Available Desde la primera descripción de la asociación entre enfermedad renal crónica y enfermedad cardiaca, los estudios epidemiológicos han confirmado y extendido el conocimiento acerca de esta relación. El riesgo de enfermedad cardiovascular se incrementa al progresar la falla renal, probablemente por la suma de los factores de riesgo no tradicionales propios de la insuficiencia renal. No solamente es la patología cardiovascular más frecuente en esta población, sino que además es sub diagnosticada y sub tratada. Los pacientes y los miembros del equipo mècdico deben ser educados acerca de este mayor riesgo cardiovascular y de las implicancias que esto tiene en el cuidado.

  12. Renal function recovery in end-stage renal disease.

    Science.gov (United States)

    Pichette, V; Quérin, S; Desmeules, M; Ethier, J; Copleston, P

    1993-09-01

    Renal function recovery (RFR) is a rare event in patients with end-stage renal disease (ESRD). Although some predictive factors have been described, there are still unresolved questions. We have analyzed the Canadian Organ Replacement Register data for the 1981 to 1989 period to assess the incidence and factors predictive of RFR in a large ESRD population as well as the outcome after recovery. Renal function recovery was defined as the interruption of renal replacement therapy (RRT) for more than 3 months. Patients on RRT for < or = 45 days were excluded. Of 14,318 registered ESRD patients, 342 (2.4%) experienced RFR after 8.9 +/- 0.5 months of RRT (mean +/- SEM); 52.3% of the recoveries occurred within 6 months of initiating RRT, while 23.7% were only observed after 12 months or more. By Cox regression, patients within the following diagnostic groups had a significantly higher rate of RFR than those with primary glomerulonephritis, who are considered to comprise the reference group: myeloma (relative rate [RR] = 6.00; P < 0.001), drug-induced disease (RR = 4.21; P < 0.001), vascular/hypertensive disease (RR = 2.60; P < 0.001), and systemic disease (RR = 2.58; P < 0.001). Inversely, patients with polycystic kidneys (RR = 0.06; P = 0.004) and diabetic patients (RR = 0.56; P = 0.024) had a lower rate of RFR than those with glomerulonephritis. Men younger than 45 years had a lower rate of RFR than older men and women of all ages (P < or = 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Does Renal Artery Supply Indicate Treatment Success of Renal Denervation?

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, Axel, E-mail: axel.schmid@uk-erlangen.de [University of Erlangen-Nuremberg, Department of Radiology (Germany); Ditting, Tilmann, E-mail: tilmann.ditting@uk-erlangen.de [University of Erlangen-Nuremberg, Department of Nephrology and Hypertension (Germany); Sobotka, Paul A., E-mail: sobotka@alumni.stanford.edu [Ohio State University (United States); Veelken, Roland, E-mail: roland.veelken@uk-erlangen.de; Schmieder, Roland E., E-mail: roland.schmieder@uk-erlangen.de [University of Erlangen-Nuremberg, Department of Nephrology and Hypertension (Germany); Uder, Michael, E-mail: michael.uder@uk-erlangen.de [University of Erlangen-Nuremberg, Department of Radiology (Germany); Ott, Christian, E-mail: christian.ott@uk-erlangen.de [University of Erlangen-Nuremberg, Department of Nephrology and Hypertension (Germany)

    2013-08-01

    PurposeRenal denervation (RDN) emerged as an innovative interventional antihypertensive therapy. With the exception of pretreatment blood pressure (BP) level, no other clear predictor for treatment efficacy is yet known. We analyzed whether the presence of multiple renal arteries has an impact on BP reduction after RDN.MethodsFifty-three patients with treatment-resistant hypertension (office BP {>=} 140/90 mmHg and 24-h ambulatory BP monitoring ({>=}130/80 mmHg) underwent bilateral catheter-based RDN. Patients were stratified into one-vessel (OV) (both sides) and at least multivessel (MV) supply at one side. Both groups were treated on one vessel at each side; in case of multiple arteries, only the dominant artery was treated on each side.ResultsBaseline clinical characteristics (including BP, age, and estimated glomerular filtration rate) did not differ between patients with OV (n = 32) and MV (n = 21). Office BP was significantly reduced in both groups at 3 months (systolic: OV -15 {+-} 23 vs. MV -16 {+-} 20 mmHg; diastolic: OV -10 {+-} 12 vs. MV -8 {+-} 11 mmHg, both p = NS) as well as 6 months (systolic: OV -18 {+-} 18 vs. MV -17 {+-} 22 mmHg; diastolic: OV -10 {+-} 10 vs. -10 {+-} 12 mmHg, both p = NS) after RDN. There was no difference in responder rate (rate of patients with office systolic BP reduction of at least 10 mmHg after 6 months) between the groups.ConclusionIn patients with multiple renal arteries, RDN of one renal artery-namely, the dominant one-is sufficient to induce BP reduction in treatment-resistant hypertension.

  14. Insuficiencia renal crónica y crecimiento

    Directory of Open Access Journals (Sweden)

    T. Pasqualini

    2003-12-01

    Full Text Available El retardo de crecimiento es uno de los mayores problemas de los niños con insuficiencia renal crónica (IRC. En 77% de los varones y 71% de las mujeres con IRC diagnosticada durante la niñez, la altura adulta se halla por debajo del percentilo 3. Los factores que influencian el crecimiento antes del trasplante (Tx son las alteraciones nutricionales, metabólicas y endocrinas; post Tx: la terapia corticoidea inmunosupresora y la alteración de la función del injerto. Sesenta a 64% de los niños llegan al Tx renal con gran deterioro de talla (mediana de talla -2.5 desvíos estándar, DS, no existiendo diferencia entre el DS de talla en el momento del Tx y el DS de talla adulta. Para mejorar el crecimiento post Tx renal, se ha intentado disminuir la dosis de corticoides, administrarlos en días alternos o utilizar corticoides con menos efectos sobre el crecimiento como el deflazacort. Varios estudios demostraron que el tratamiento con hormona de crecimiento (GH es efectivo y esto condujo a que el FDA (Food and Drug Administration lo aprobara como tratamiento de los niños, antes de ser sometidos al Tx renal. La magnitud del aumento de la velocidad de crecimiento es mayor durante el tratamiento conservador, post Tx algo menor, observándose la menor respuesta durante la diálisis. Asimismo, la ganancia de talla se correlaciona con mayor duración del tratamiento con GH durante la etapa prepuberal. Como conclusión, si el deterioro de talla es importante, lo ideal es comenzar el tratamiento a edades tempranas, en la etapa del tratamiento conservador, tratar de acortar el tiempo de diálisis, lograr una talla mejor al momento del Tx, teniendo en cuenta que la talla final está fuertemente relacionada con la talla alcanzada al momento del primer Tx.Many children with chronic renal insufficiency (CRI show growth retardation. Our objective is to describe the natural history of growth in patients with CRI, its pathogenesis and its optimization. Final

  15. Acute renal failure in the newborn.

    Science.gov (United States)

    Andreoli, Sharon Phillips

    2004-04-01

    Acute renal failure in the newborn is a common problem and is typically classified as prerenal, intrinsic renal disease including vascular insults, and obstructive uropathy. In the newborn, renal failure may have a prenatal onset in congenital diseases such as renal dysplasia with or without obstructive uropathy and in genetic diseases such as autosomal recessive polycystic kidney disease. Acute renal failure in the newborn is also commonly acquired in the postnatal period because of hypoxic ischemic injury and toxic insults. Nephrotoxic acute renal failure in newborns is usually associated with aminoglycoside antibiotics and nonsteroidal anti-inflammatory medications used to close a patent ductus arteriosis. Alterations in renal function occur in approximately 40% of premature newborns who have received indomethacin and such alterations are usually reversible. Renal artery thrombosis and renal vein thrombosis will result in renal failure if bilateral or if either occurs in a solitary kidney. Cortical necrosis is associated with hypoxic/ischemic insults due to perinatal anoxia, placenta abruption and twin-twin or twin-maternal transfusions with resultant activation of the coagulation cascade. As in older children, hospital acquired acute renal failure is newborns is frequently multifactorial in origin. Although the precise incidence and prevalence of acute renal failure in the newborn is unknown, several studies have shown that acute renal failure is common in the neonatal intensive care unit. Recent interesting studies have demonstrated that some newborns may have genetic risks factors for acute renal failure. Once intrinsic renal failure has become established, management of the metabolic complications of acute renal failure continues to involve appropriate management of fluid balance, electrolyte status, acid-base balance, nutrition and the initiation of renal replacement therapy when appropriate. Renal replacement therapy may be provided by peritoneal dialysis

  16. Meningite e endocardite infecciosa causada por Rhodotorula mucilaginosa em paciente imunocompetente

    Directory of Open Access Journals (Sweden)

    Sergio Henrique Loss

    2011-12-01

    Full Text Available Os autores relatam o caso de um homem imunocompetente admitido com comprometimento agudo do sistema nervoso, crise hipertensiva e insuficiência renal, vindo a receber diagnóstico de meningite e endocardite infecciosa por Rhodotorula mucilaginosa. Até onde sabemos, esta é a primeira descrição de infecção simultânea das meninges e do endotélio causada por Rhodotorula em um paciente sem comprometimento imunológico.

  17. Agregação familiar da doença renal crônica secundária à hipertensão arterial ou diabetes mellitus: estudo caso-controle

    OpenAIRE

    Fernando Antonio de Almeida; Giuliano Serafino Ciambelli; André Luz Bertoco; Marcelo Mai Jurado; Guilherme Vasconcelos Siqueira; Eder Augusto Bernardo; Maria Valeria Pavan; Reinaldo José Gianini

    2015-01-01

    No Brasil, a hipertensão e o diabetes mellitus tipo 2 são responsáveis por 60% dos casos de doença renal crônica terminal em terapia renal substitutiva. Estudos americanos identificaram agregação familiar da doença renal crônica, predominante em afrodescendentes. Um único estudo brasileiro observou agregação familiar entre portadores de doença renal crônica quando comparados a indivíduos internados com função...

  18. [Renal abnormalities in Down syndrome: A review].

    Science.gov (United States)

    Niamien-Attai, C; Bacchetta, J; Ranchin, B; Sanlaville, D; Cochat, P

    2017-10-01

    Down syndrome (DS) is often associated with cardiac malformations, so that kidney damage is little known. The objective of this study was to present the diversity of renal abnormalities and their potential progression to chronic renal failure. Among congenital abnormalities of the kidney and urinary tract (CAKUT) abnormalities appear to be frequent: pyelectasis, megaureters, posterior urethra valves, as well as renal malformations such as renal hypoplasia, horseshoe kidney, or renal ectopia. Contributing factors to acute kidney failure have been described in patients with DS: bilateral lesions and minor renal injury, such as glomerular microcysts, tubular dilation, and immature glomeruli. Histological lesions can be found, albeit nonspecific; they occur earlier than in the general population. Two metabolic specificities have also been described: decreased clearance of uric acid and a hypercalciuria by passive hyperabsorption. End-stage renal disease can occur, thus raising the problem of the best choice of management. In conclusion, renal abnormalities in patients in DS should be known so as to preserve a good renal functional prognosis: systematic screening with renal ultrasound can be proposed. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  19. Focus on renal congestion in heart failure.

    Science.gov (United States)

    Afsar, Baris; Ortiz, Alberto; Covic, Adrian; Solak, Yalcin; Goldsmith, David; Kanbay, Mehmet

    2016-02-01

    Hospitalizations due to heart failure are increasing steadily despite advances in medicine. Patients hospitalized for worsening heart failure have high mortality in hospital and within the months following discharge. Kidney dysfunction is associated with adverse outcomes in heart failure patients. Recent evidence suggests that both deterioration in kidney function and renal congestion are important prognostic factors in heart failure. Kidney congestion in heart failure results from low cardiac output (forward failure), tubuloglomerular feedback, increased intra-abdominal pressure or increased venous pressure. Regardless of the cause, renal congestion is associated with increased morbidity and mortality in heart failure. The impact on outcomes of renal decongestion strategies that do not compromise renal function should be explored in heart failure. These studies require novel diagnostic markers that identify early renal damage and renal congestion and allow monitoring of treatment responses in order to avoid severe worsening of renal function. In addition, there is an unmet need regarding evidence-based therapeutic management of renal congestion and worsening renal function. In the present review, we summarize the mechanisms, diagnosis, outcomes, prognostic markers and treatment options of renal congestion in heart failure.

  20. Retrograde Renal Cooling to Minimize Ischemia

    Directory of Open Access Journals (Sweden)

    Janet L. Colli

    2013-01-01

    Full Text Available Objective: During partial nephrectomy, renal hypothermia has been shown to decrease ischemia induced renal damage which occurs from renal hilar clamping. In this study we investigate the infusion rate required to safely cool the entire renal unit in a porcine model using retrograde irrigation of iced saline via dual-lumen ureteral catheter. Materials and Methods: Renal cortical, renal medullary, bowel and rectal temperatures during retrograde cooling in a laparoscopic porcine model were monitored in six renal units. Iced normal saline was infused at 300 cc/hour, 600 cc/hour, 1000 cc/hour and gravity (800 cc/hour for 600 seconds with and without hilar clamping. Results: Retrograde cooling with hilar clamping provided rapid medullary renal cooling and significant hypothermia of the medulla and cortex at infusion rates ≥ 600 cc/hour. With hilar clamping, cortical temperatures decreased at -0.9° C/min. reaching a threshold temperature of 26.9° C, and medullary temperatures decreased at -0.90 C/min. reaching a temperature of 26.1° C over 600 seconds on average for combined data at infusion rates ≥ 600 cc/hour. The lowest renal temperatures were achieved with gravity infusion. Without renal hilum clamping, retrograde cooling was minimal at all infusion rates. Conclusions: Significant renal cooling by gravity infusion of iced cold saline via a duel lumen catheter with a clamped renal hilum was achieved in a porcine model. Continuous retrograde irrigation with iced saline via a two way ureteral catheter may be an effective method to induce renal hypothermia in patients undergoing robotic assisted and/or laparoscopic partial nephrectomy.

  1. Acute renal infarction: a case series.

    Science.gov (United States)

    Bourgault, Marie; Grimbert, Philippe; Verret, Catherine; Pourrat, Jacques; Herody, Michel; Halimi, Jean Michel; Karras, Alexandre; Amoura, Zahir; Jourde-Chiche, Noémie; Izzedine, Hassan; François, Hélène; Boffa, Jean-Jacques; Hummel, Aurélie; Bernadet-Monrozies, Pauline; Fouque, Denis; Canouï-Poitrine, Florence; Lang, Philippe; Daugas, Eric; Audard, Vincent

    2013-03-01

    Renal infarction is an arterial vascular event that may cause irreversible damage to kidney tissues. This study describes the clinical characteristics of patients with renal infarction according to underlying mechanism of vascular injury. This study retrospectively identified 94 patients with renal infarction diagnosed between 1989 and 2011 with the aim of highlighting potential correlations between demographic, clinical, and biologic characteristics and the etiology of renal infarction. Four groups were identified: renal infarction of cardiac origin (cardiac group, n=23), renal infarction associated with renal artery injury (renal injury group, n=29), renal infarction associated with hypercoagulability disorders (hypercoagulable group, n=15), and apparently idiopathic renal infarction (idiopathic group, n=27). Clinical symptoms included abdominal and/or flank pain in 96.8% of cases; 46 patients had uncontrolled hypertension at diagnosis. Laboratory findings included increase of lactate dehydrogenase level (90.5%), increase in C-reactive protein level (77.6%), and renal impairment (40.4%). Compared with renal injury group patients, this study found that cardiac group patients were older (relative risk for 1 year increase=1.21, P=0.001) and displayed a lower diastolic BP (relative risk per 1 mmHg=0.94, P=0.05). Patients in the hypercoagulable group had a significantly lower diastolic BP (relative risk=0.86, P=0.005). Patients in the idiopathic group were older (relative risk=1.13, P=0.01) and less frequently men (relative risk=0.11, P=0.02). Seven patients required hemodialysis at the first evaluation, and zero patients died during the first 30 days. This study suggests that the clinical and biologic characteristics of patients can provide valuable information about the causal mechanism involved in renal infarction occurrence.

  2. Simulation of human renal system.

    Science.gov (United States)

    Mahmood, Haydar A; Botros, Nazeih M

    2013-01-01

    The goal of this study is to develop a synthesisable computer-simulated model that mimics the function of a simplified renal system. Hardware description language has been used to simulate the model. In future phase of this study, the model will be realised on an electronic chip such as 'Field Programmable Gate Arrays'. The simulated model introduces a dynamic representation of the human body fluid balance under normal conditions and displays the change of urine flow with the amount of ingested water. The inputs of the model are average values of parameters extracted from the renal system. Some of these parameters and variables are: arterial pressure, daily ingested fluid volume, daily ingested sodium, daily ingested potassium, extracellular fluid volume, intracellular fluid volume, renin concentration, angiotensin II concentration, and aldosterone concentration. Our results show that the output of the model is in agreement with those of the literatures.

  3. Transjugular renal biopsy in the treatment of patients with cirrhosis and renal abnormalities.

    Science.gov (United States)

    Jouët, P; Meyrier, A; Mal, F; Callard, P; Guettier, C; Stordeur, D; Trinchet, J C; Beaugrand, M

    1996-11-01

    When renal lesions are suspected in patients with cirrhosis, clotting disorders often preclude percutaneous renal biopsy. This study was undertaken to determine whether transjugular renal biopsy is possible, safe, and useful in such patients. From 1987 to 1994, 70 patients with cirrhosis and clotting disorders underwent transjugular renal biopsies, providing renal tissue in 55. Of these 55 patients, 41 were Child-Pugh class B or C, 35 were alcoholic, serum creatinine levels were > or = 130 micromol/L in 46, and proteinuria was > or = 0.5 g/d in 37. Clinically significant complications of transjugular renal biopsy were persistent hematuria in 4 and perirenal hematoma in 4, requiring blood transfusions in 1 and 2 cases, respectively. There were no deaths related to renal biopsy. Renal lesions were identified as glomerular in 41 (74.5%), interstitial in 7, and end-stage in 2 and were absent in 5. Transjugular renal biopsy influenced treatment in 21 patients (38%), including 11 who were proposed for liver transplantation and 4 who had chronic liver rejection. Decisions based on results of transjugular renal biopsy were to perform liver transplantation in 8 and combined renal and liver transplantation in 5, whereas 2 were refused. In 6 other patients, the results of renal biopsy modified the medical regimen. We conclude that transjugular renal biopsy may be a useful procedure in patients with cirrhosis and clotting disorders. This technique does not entail undue risks and may influence treatment decisions, particularly in patients proposed for liver transplantation.

  4. [Renal markers and predictors, and renal and cardiovascular risk factors].

    Science.gov (United States)

    Fernández-Andrade, C

    2002-01-01

    An important task of the nephrologists during the last century, it has been the search of elements and means that allow us, with the adequate precision, to correlate the functional deterioration of the kidney, and the patient's clinical reality. And the continuous searching of factors and markers that injure them, the prognosis, and early diagnosis, to be able to predict the degree of the organs and patient's survival. Almost parallel survival presage in the natural history of the illness, almost one century ago. In the second half of the XX century, in the developed countries, appear modifications of the social, cultural, and sanitary conditions, that make appear some very different partner-sanitary and epidemic circumstances, and take place like they are, among others: 1. An increase of per cápita private rents, what takes place to increase of the level of social life and the population's health. With increment of the longevity, and smaller incidence and prevalence of classic process, as malnutrition, infections, infantile mortality, so increasing the weight of the cardiovascular diseases and death. This is potentiated for the increment and the incidence of environmental cardiovascular risk's factors (like high caloric and fatty-rich diets, smoke, alcohol, disappearance of the physical work, inactivity, etc). And that situations are also product of the change of the outline of human and social values and guides. 2. Access of the whole population to a sanitary attention of more quality and effectiveness. It allows the biggest survival of patients that suffer vascular crisis, (as angina, miocardial infarction or cerebrovascular accident), that few years ago they have had a higher morbimortality and an inferior survival (2). 3. The execution of big epidemic studies has been able to, not only characterize and test with scientific evidence to numerous factors and markers, that induce renal and cardiovascular prejudicial changes, but risk and death probability

  5. Leiomyoma in a Renal Allograft

    Directory of Open Access Journals (Sweden)

    Yan Jun Li

    2016-01-01

    Full Text Available Leiomyomas are smooth muscle tumours that are rarely found in the kidney. There is one report of a leiomyoma in a kidney transplant in a paediatric recipient. Here, we report an adult renal transplant recipient who developed an Epstein-Barr virus-positive leiomyoma in his allograft 15 years after transplantation. The patient was converted to everolimus for posttransplant immunosuppression management and there was no sign of progression over a year.

  6. Opportunistic infections following renal transplantation

    Directory of Open Access Journals (Sweden)

    Rao K

    2002-01-01

    Full Text Available Opportunistic infection is common following renal transplantation. Prompt diagnosis and management can be life saving. Four different types of opportunistic respiratory infections diagnosed at our center during the period of January 1998 to December 2000 are discussed. Of the four cases one had Aspergillus, second had Sporothrix, third had Nocardia and fourth case Actinomyces species. Microbiologist has an important role to play by being aware of such opportunistic infections and helping the clinician to make early aetiological diagnosis.

  7. Primary renal neoplasia of dogs.

    Science.gov (United States)

    Bryan, Jeffrey N; Henry, Carolyn J; Turnquist, Susan E; Tyler, Jeff W; Liptak, Julius M; Rizzo, Scott A; Sfiligoi, Gabriella; Steinberg, Steven J; Smith, Annette N; Jackson, Tarraca

    2006-01-01

    Primary renal tumors are diagnosed uncommonly in dogs. Signs and survival will differ among different categories of primary renal tumors. Data were collected from the medical records of 82 dogs with primary renal tumors diagnosed by examination of tissue obtained by ultrasound-guided biopsy, needle aspiration, surgery, or at postmortem examination. This was a multi-institutional, retrospective study. Forty-nine dogs had carcinomas, 28 had sarcomas, and 5 had nephroblastomas. The dogs were geriatric (mean 8.1 years; range: 1-17) with a weight of 24.9 kg (range: 4.5-80). Tumors occurred with equal frequency in each kidney with 4% occurring bilaterally. Initial signs included one or more of hematuria, inappetance, lethargy. weight loss, or a palpable abdominal mass. Pain was reported more frequently in dogs with sarcomas (5/28). The most common hematologic abnormalities were neutrophilia (22/63), anemia (21/64), and thrombocytopenia (6/68). Polycythemia was present in 3 dogs and resolved with treatment. Hematuria (28/49), pyuria (26/49), proteinuria (24/50), and isosthenuria (20/56) were the most frequently observed abnormalities on urinalysis. Pulmonary metastases were noted on thoracic radiographs in 16% of dogs at diagnosis. Seventy-seven percent of dogs had metastatic disease at the time of death. Median survival for dogs with carcinomas was 16 months (range 0-59 months), for dogs with sarcomas 9 months (range 0-70 months), and for dogs with nephroblastomas 6 months (range 0-6 months). Primary renal tumors in dogs are generally highly malignant with surgery being the only treatment that improves survival.

  8. Jeune syndrome with renal failure

    OpenAIRE

    Peco-Antić Amira; Kostić Mirjana; Spasojević Brankica; Miloševski-Lomić Gordana; Paripović Dušan; Kruščić Divna; Cvetković Mirjana

    2017-01-01

    Introduction/Objective. Jeune syndrome (JS) is a rare hereditary ciliopathy characterized by asphyxiating thoracic dystrophy, shortened limbs and brachydactyly. Extraskeletal anomalies such as chronic renal failure (CRF), hepatic fibrosis, and retinitis pigmentosa may be a part of the JATD phenotype. The aim of this study is to present long-term follow-up of JS patients with early progressive kidney disease. Methods. This is a retrospective study of pediatric patients with JS and CRF who were...

  9. Renal Dialysis and its Financing.

    Science.gov (United States)

    Borelli, Marisa; Paul, David P; Skiba, Michaeline

    2016-01-01

    The incidence of end-stage renal disease (ESRD) and its associated comorbidities such as diabetes and hypertension continue to increase as the population ages. As most ESRD patients qualify for Medicare coverage, the U.S. government initiated reforms of the payment system for dialysis facilities in an effort to decrease expenditures associated with ESRD reimbursement. The effects of reduced reimbursement rates, bundled payment options, and quality incentives on the current dialysis system, including kidney dialysis units, physicians, and patients, are examined.

  10. Insuficiência renal de evolução silenciosa

    OpenAIRE

    Diogo Santos, Sara; Aguiar, Marta; Mendonça, Erica; Almeida, Margarida

    2014-01-01

    Resumo: A nefronoftisis é uma entidade clínico-patológica hereditária recessiva que se enquadra num complexo clínico designado por nefronoftisis/doença quística medular e se caracteriza por nefropatia tubulo-intersticial crónica e progressiva que conduz sempre a insuficiência renal crónica terminal. Descreve-se o caso de uma adolescente de 12 anos de idade com agudização de insuficiência renal crónica de evolução silenciosa, com sintomatologia inicial inespecífica, não valorizada de poliúria ...

  11. Neumonía por citomegalovirus en el adulto inmunocompetente

    Directory of Open Access Journals (Sweden)

    Alfredo Jane Lara

    Full Text Available Introducción: la Neumonía por Citomegalovirus (CMV es una entidad rara en los pacientes inmunocompetentes, pero cuando se asocia con otras enfermedades como la neumonía, puede ser altamente letal. Objetivo: presentar un caso infrecuente de infección primaria por Citomegalovirus complicado con neumonía. Presentación del caso: se presenta el caso de una paciente de 36 años de edad, que trabajaba directamente con pacientes trasplantados renales, y que acudió a consulta por presentar fiebre de 38 ºC en un período de más de 10 días,precedida de escalofríos, dolor de garganta, tos seca al inicio y luego expectoración de color verde claro; examen físico negativo; todo lo anterior acompañado de astenia marcada durante todo el día y anorexia. La falta de respuesta adecuada al tratamiento con Levofloxacino y Azitromicina nos hizo sospechar la presencia de una Neumonía viral por un germen de etiología no habitual, por lo que se le indicaron exámenes de anticuerpos anti-virales, resultando positivo para Citomegalovirus. Conclusiones: existen procesos inflamatorios pulmonares agudos reversibles de causa infecciosa sin manifestaciones auscultatorias, es decir con disociación clínico-radiológica, que en su mayoría corresponden a procesos de índole viral, y que además no son exclusivos de pacientes inmunodeprimidos.

  12. Expresión de renina en oncocitomas renales = Renin expression in renal oncocytomas

    Directory of Open Access Journals (Sweden)

    Franco Tavera, Óscar Andrés

    2010-12-01

    Full Text Available Introducción: algunos tumores renales han sido asociados con secreción de hormonas, incluyendo renina. Nuestro objetivo fue investigar la frecuencia de expresión de esta hormona en un tumor renal epitelial infrecuente, el oncocitoma, y si esta expresión se asocia con hipertensión arterial sistémica (HTA.Métodos: examinamos una serie de 13 oncocitomas (provenientes de igual número de pacientes usando un anticuerpo monoclonal para detectar la hormona por inmunohistoquímica, y su asociación con HTA. Las características de la inmunotinción se evaluaron microscópicamente. Obtuvimos, de los archivos de historias, las características clínicas y de la presión arterial sistémica antes y después de la resección tumoral.Resultados: ocho de los 13 tumores (61,5% tenían inmunorreactividad para renina, en todos ellos difusa. En tres casos la inmunomarcación fue como un punto paranuclear (dot-like y en otros tres estaba en la porción apical del citoplasma de las células neoplásicas. En tres de los ocho casos con expresión de renina (37,5% y en tres de los cinco sin dicha expresión (60,0% se detectó HTA (p = 0,59. Después de la resección tumoral ninguno de los pacientes con expresión de renina e HTA mostró remisión de esta.Conclusión: la renina se expresa frecuentemente en oncocitomas renales pero es clínicamente inactiva. Serán necesarios más estudios para conocer las implicaciones de esta expresión en la presentación clínica, el diagnóstico y la histogénesis.

  13. Microvascular Disease After Renal Transplantation

    Directory of Open Access Journals (Sweden)

    Qi Lun Ooi

    2015-11-01

    Full Text Available Background/Aims: Individuals who reach end-stage kidney disease (CKD5 have a high risk of vascular events that persists even after renal transplantation. This study compared the prevalence and severity of microvascular disease in transplant recipients and patients with CKD5. Methods: Individuals with a renal transplant or CKD5 were recruited consecutively from renal clinics, and underwent bilateral retinal photography (Canon CR5-45, Canon. Their retinal images were deidentified and reviewed for hypertensive/microvascular signs by an ophthalmologist and a trained grader (Wong and Mitchell classification, and for vessel caliber at a grading centre using a computer-assisted method and Knudtson's modification of the Parr-Hubbard formula. Results: Ninety-two transplant recipients (median duration 6.4 years, range 0.8 to 28.8 and 70 subjects with CKD5 were studied. Transplant recipients were younger (pConclusions: Hypertensive/microvascular disease occurred just as often and was generally as severe in transplant recipients and subjects with CKD5. Microvascular disease potentially contributes to increased cardiac events post- transplantation.

  14. Radiologic findings in renal oncocytoma

    Energy Technology Data Exchange (ETDEWEB)

    Tikkakoski, T.; Paeivaensalo, M.; Alanen, A.; Nurmi, M.; Taavitsainen, M.; Farin, P.; Apaja-Sarkkinen, M. (Oulu Univ. Central Hospitals in Oulu, Turku, Helsinki, and Kuopio (Finland). Depts. of Diagnostic Radiology, Surgery, and Pathology)

    1991-09-01

    The imaging findings of 36 renal oncocytomas in 32 patients were evaluated retrospectively. Twenty-two patients underwent ultrasound (US), 16 CT, 25 angiography, 19 urography, and 6 fine-needle biopsy. At US 8 of the oncocytomas were isoechoic, 7 hyperechoic, and 7 hypoechoic. The structure was homogeneous in 59% and nonhomogeneous in 41%. At plain CT 12 oncocytomas were homogeneously hypodense, 3 isodense, and one hyperdense. Contrast enhancement was homogeneous in 10 and inhomogeneous in 4 cases. A stellate scar was detected in one case, and in one case a contrast study was not performed. At angiography the oncocytomas were hypervascular in 21, hypovascular in 3 cases, and one was not detected. Nineteen of the tumors were well delineated. A spoke-wheel arterial pattern was detected in 3 tumors. The cytologic diagnosis was benign renal oncocytoma in 4 cases and highly suggestive of oncocytoma in 2 cases. We conclude that the homogeneity of a renal tumor at US and at CT may suggest the possibility of oncocytoma. US-guided fine-needle biopsy is a useful diagnostic tool in patients who need a precise presurgical diagnosis. (orig.).

  15. Pregnancy in renal transplant recipients.

    Science.gov (United States)

    Bouattar, T; Hakim, H; Rhou, H; Benamar, L; Bayahia, R; Ouzeddoun, N

    2009-06-01

    Renal transplantation with a well-functioning graft leads to a rapid restoration of endocrine and sexual functions. The aim of this study was to examine our experience with pregnancies among renal transplant patients, particularly with regard to their impact on graft function. We analyzed 10 pregnancies in 7 renal transplant recipients for long-term graft outcomes in terms of clinical and biological data. The mean patient age was 28.5 +/- 4 years. They all received a living donor kidney. The time between transplantation and the onset of pregnancy was 33.4 +/- 23.2 months. Regarding the immunosuppressive therapy, all patients received steroids and cyclosporine; 4 patients received in addition azathioprine and 2 received mycophenolate mofetil that was changed at 1 month before conception to azathioprine. There was no significant difference between the serum creatinine before and during pregnancy. We did not observe any acute rejection episode. Pregnancy complications were preclampsia in 1 case, hypertension in 1 case, urinary tract infection in 2 cases, and anemia in 80% of patients during the third trimester. Premature rupture of membranes occurred in 1 case and preterm delivery in 2 cases. Two cases of neonatal death were registered. Cesarean section was performed in 50% of cases. The follow-up revealed 2 cases of chronic rejection. A multidisciplinary approach is necessary for pregnancy which generally occurs at 2 years after kidney transplantation.

  16. Jeune syndrome with renal failure

    Directory of Open Access Journals (Sweden)

    Peco-Antić Amira

    2017-01-01

    Full Text Available Introduction/Objective. Jeune syndrome (JS is a rare hereditary ciliopathy characterized by asphyxiating thoracic dystrophy, shortened limbs and brachydactyly. Extraskeletal anomalies such as chronic renal failure (CRF, hepatic fibrosis, and retinitis pigmentosa may be a part of the JATD phenotype. The aim of this study is to present long-term follow-up of JS patients with early progressive kidney disease. Methods. This is a retrospective study of pediatric patients with JS and CRF who were treated at the University Children’s Hospital between January 1980 and December 2014. The patients’ data were retrospectively reviewed from the medical records. Results. There were thirteen patients from 11 families, five girls and eight boys mean aged 4.3 years at the time of diagnosis. All of the patients had characteristic skeletal findings, retinal degeneration and an early onset of CRF at age range from 1.5 to 7 years. Five patients had neonatal respiratory distress and congenital liver fibrosis was diagnosed in five patients. One patient died due to complications of CRF, while others survived during follow-up of mean 11 years. IFT140 mutations were found in four genetically tested patients. Conclusion. The average incidence rate of JS with renal phenotype in Serbia was about 0.2 per one million of child population. Long-term survival of JS patients depends on renal replacement therapy, while skeletal dysplasia, growth failure, respiratory and eyes problems have impact on the patients’ quality of life.

  17. Monoclonal gammopathies of renal significance.

    Science.gov (United States)

    Caravaca-Fontán, Fernando; Gutiérrez, Eduardo; Delgado Lillo, Ramón; Praga, Manuel

    The term monoclonal gammopathy of renal significance (MGRS) comprises a group of diseases pathogenetically characterised by proliferation of a B-cell or plasma cell clone that synthesises and secretes a monoclonal immunoglobulin or its components (light and/or heavy chains), that may deposit and cause glomerular, tubular, interstitial and/or vascular damage. The importance of differentiating the term MGRS from other monoclonal gammopathies lies in the fact that diagnostic and therapeutic procedures aimed at controlling monoclonal protein synthesis and secretion can be indicated, irrespective of the classic criteria based on malignant tumour expansion. Renal pathology associated with MGRS is highly heterogeneous, and therefore renal biopsy should be considered a key diagnostic tool. A precise diagnostic approach, however, must also identify the monoclonal protein in plasma and/or in urine, together with a complete haematological study in order to determine the nature and extension of cell clones. Recent advances in the understanding of these entities have resulted in significant improvements in clinical course and survival in several forms of MGRS, although more studies and clinical experience are needed in order to delineate more effective therapeutic strategies. In this review, we summarise the main clinical and pathological features of MGRS, highlighting the most appropriate diagnostic approach and current therapeutic options. Copyright © 2017 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.

  18. Sangrado de angiomiolipoma renal en paciente con síndrome de genes contiguos (TSC2/PKD1 tras 17 años de tratamiento renal sustitutivo

    Directory of Open Access Journals (Sweden)

    Mónica Furlano

    2017-01-01

    Full Text Available Presentamos el caso de un varón de 32 años, con síndrome de genes contiguos TSC2/PKD1, que le ocasiona esclerosis tuberosa (ET y poliquistosis renal autosómica dominante simultáneamente. Evolucionó a enfermedad renal terminal y se realizó trasplante renal a los 12 años. Los riñones presentaban angiomiolipomas (AML, que son tumores benignos frecuentes en pacientes con ET. A los 17 años postrasplante, presentó un cuadro de dolor abdominal, anemización y hematoma retroperitoneal. Dicho hematoma se produjo por el sangrado de los AML. Como tratamiento se realizó embolización selectiva. Nuestro paciente podría haberse beneficiado en el momento del trasplante renal del tratamiento con inhibidores de mTOR. Este fármaco actúa como inmunosupresor y reductor tumoral en la ET, al disminuir el riesgo de rotura y hemorragia. En este paciente no se administró porque cuando se trasplantó no se conocía la relación de los inhibidores de mTOR con la ET. Este caso confirma que, a pesar de tratarse de pacientes trasplantados o en diálisis, el riesgo de sangrado por los AML persiste, por lo cual se propone realizar controles periódicos de los riñones propios y valorar la nefrectomía.

  19. Advanced renal disease, end-stage renal disease and renal death among HIV-positive individuals in Europe

    DEFF Research Database (Denmark)

    Ryom, L; Kirk, O; Lundgren, Jens

    2012-01-01

    in EuroSIDA. ARD was defined as confirmed eGFR 3 months apart) using Cockcroft-Gault. ESRD was defined as hemo- or peritoneal dialysis>1 month/renal transplant. Renal deaths were defined as renal failure as the underlying cause of death, using CoDe methodology. Patients were...... followed from baseline (first eGFR after 1/1/2004) until last eGFR, ARD/ESRD/renal death; whichever occurred first. Poisson regression was used to identify predictors. 8817 persons were included, the majority were white (87.3%), males (73.9%) infected though homosexual contact (41.5%) and with a median age...

  20. Detection of acute renal allograft rejection by analysis of renal tissue proteomics in rat models of renal transplantation

    Directory of Open Access Journals (Sweden)

    Dai Yong

    2008-01-01

    Full Text Available At present, the diagnosis of renal allograft rejection requires a renal biopsy. Clinical management of renal transplant patients would be improved if rapid, noninvasive and reliable biomarkers of rejection were available. This study is designed to determine whether such protein biomarkers can be found in renal-graft tissue proteomic approach. Orthotopic kidney transplantations were performed using Fisher (F344 or Lewis rats as donors and Lewis rats as recipients. Hence, there were two groups of renal transplant models: one is allograft (from F344 to Lewis rats; another is syngrafts (from Lewis to Lewis rats serving as control. Renal tissues were collected 3, 7 and 14 days after transplantation. As many as 18 samples were analyzed by 2-D Electrophoresis and mass spectrometry (MALDI-TOF-TOF-MS. Eleven differentially expressed proteins were identified between groups. In conclusion, proteomic technology can detect renal tissue proteins associated with acute renal allograft rejection. Identification of these proteins as diagnostic markers for rejection in patients′ urine or sera may be useful and non-invasive, and these proteins might serve as novel therapeutic targets that also help to improve the understanding of mechanism of renal rejection.

  1. Doença cardiovascular e fatores de risco cardiovascular em candidatos a transplante renal Cardiovascular disease and risk factors in candidates for renal transplantation

    Directory of Open Access Journals (Sweden)

    Luís Henrique Wolff Gowdak

    2005-02-01

    Full Text Available OBJETIVO: Determinar a prevalência de doença cardiovascular (DCV e de fatores de risco tradicionais em portadores de insuficiência renal crônica em avaliação para inclusão em lista para transplante renal. MÉTODOS: Foram submetidos à avaliação clínica e exames complementares 195 pacientes com insuficiência renal crônica dialítica e comparados a grupo de 334 hipertensos pareados por idade. As equações de Framingham foram usadas para o cálculo do risco absoluto (RA; o risco relativo (RR foi calculado tendo como referência o risco absoluto da coorte de baixo risco de Framingham. RESULTADOS: Do total, 37% apresentaram algum tipo de doença cardiovascular na avaliação inicial, sendo que arteriopatia obstrutiva (23% foi a mais prevalente. Excluídos os pacientes com doença cardiovascular, em relação aos fatores de risco tradicionais, houve diferença significativa quanto à pressão arterial sistólica e colesterol total (maiores no grupo de hipertensos e às prevalências de homens, diabetes e tabagismo, maiores no grupo de insuficiência renal crônica, que apresentou maior grau de hipertrofia ventricular esquerda, menor pressão arterial diastólica e menor prevalência de história familiar de doença cardiovascular e obesidade. O risco relativo para doença cardiovascular dos pacientes com insuficiência renal crônica foi mais elevado em relação à população controle de Framingham porém não diferiu da observada no grupo de hipertensos. CONCLUSÃO: Em candidatos a transplante renal é significativa a prevalência de doença cardiovascular e de fatores de risco tradicionais; as equações de Framingham não quantificam adequadamente o risco cardiovascular real e outros fatores de risco específicos desta população devem contribuir para o maior risco cardiovascular.OBJECTIVE: To determine the prevalence of cardiovascular disease (CVD and traditional risk factors in patients with chronic renal failure undergoing

  2. Nefropatia por IgA: reporte de un caso

    Directory of Open Access Journals (Sweden)

    Jessica Bravo Zúñiga

    2005-07-01

    Full Text Available La nefropatía por IgA es una glomerulonefritis inmune que involucra un grupo heterogéneo de pacientes con una variedad de diferentes presentaciones clínicas. Una niña de 4 años de edad acude con historia de 2 meses de enfermedad caracterizada por hematuria intermitente, sin sintomatología miccional. El examen físico solo muestra edema palpebral. El examen de orina revela hematuria macroscópica (3+ y proteinuria 3(+, El estudio sonográfico y la urografía excretoria no mostraron alteraciones; su nivel de hemoglobina, leucocitos y depuración de creatinina fueron normales. La excreción de proteínas en orina fue de 45mg/m2/h. Los niveles de C3 y C4 estuvieron en limites normales.Se procede a una biopsia renal la cual expone un incremento difuso en las células mesangiales con engrosamiento de la matriz y algunas zonas de necrosis. El examen de inmunofluorescencia mostró depósitos mesangiales de Ig A y C3, todos los hallazgos son compatibles con Nefropatía por Ig A. (Rev Med Hered 2005;16:223-227.

  3. Características de los pacientes en espera de trasplante renal

    Directory of Open Access Journals (Sweden)

    Fernanda Prieto

    2015-04-01

    Full Text Available Los pacientes con insuficiencia renal crónica presentan un marcado descenso de la tasa de filtración glomerular por lo que requieren de terapia de reemplazo renal como la diálisis o el trasplante para sobrevivir. El objetivo del estudio fue determinar las características de los pacientes en lista de espera para trasplante renal. Analizamos 156 pacientes provenientes de diversos centros de diálisis que acudieron al Laboratorio Central de Salud Pública entre julio de 2.013 y agosto de 2.014. Se recolectaron datos demográficos y muestras de sangre para determinar la presencia de anticuerpos anti-HLA por ELISA. Las edades estaban comprendidas entre 4 y 74 años, con un promedio de 40 años. Se registraron pacientes de 15 de las 18 Regiones Sanitarias del país, 50% de los cuales provenían de Asunción y del Departamento Central. La cobertura médica se encontró dividida en partes iguales entre el Ministerio de Salud Pública y el Instituto de Previsión Social. El tiempo promedio en diálisis fue de 34 meses, el 66% de los pacientes fueron poli-transfundidos, el 13% candidatos a retrasplante y el 34% de las mujeres fueron multíparas. El 36% de la población estudiada presentó anticuerpos anti-HLA. Se concluye que los pacientes en espera de trasplante renal se caracterizan por encontrarse en plena edad productiva y por permanecer en diálisis durante varios años. Además, un tercio de esta población se encuentra inmunizada frente a antígenos de histocompatibilidad, lo que dificulta su acceso al trasplante.

  4. Primary renal MALToma: A rare differential diagnosis for a recurrent renal mass after primary ablative therapy

    Science.gov (United States)

    Vedovo, Francesca; Pavan, Nicola; Liguori, Giovanni; Siracusano, Salvatore; Bussani, Rossana; Trombetta, Carlo

    2014-01-01

    We report a case of primary renal lymphoma of mucosa-associated lymphoid tissue in an 82-year-old woman. She presented with a history of renal mass previously treated with kidney percutaneous cryoablation at another centre. PMID:25024802

  5. Urinary potassium excretion, renal ammoniagenesis, and risk of graft failure and mortality in renal transplant recipients

    NARCIS (Netherlands)

    Eisenga, Michele F.; Kieneker, Lyanne M.; Soedamah-Muthu, Sabita S.; van den Berg, Else; Deetman, Petronella E.; Navis, Gerjan J.; Gans, Reinold O. B.; Gaillard, Carlo A. J. M.|info:eu-repo/dai/nl/073810339; Bakker, Stephan J. L.; Joosten, Michel M.

    2016-01-01

    Background: Renal transplant recipients (RTRs) have commonly been urged to limit their potassium intake during renal insufficiency and may adhere to this principle after transplantation. Importantly, in experimental animal models, low dietary potassium intake induces kidney injury through

  6. Emerging roles for eicosanoids in renal diseases.

    Science.gov (United States)

    Câmara, Niels O S; Martins, Joilson O; Landgraf, Richardt G; Jancar, Sonia

    2009-01-01

    Eicosanoids are products of arachidonic acid metabolism which have important roles in renal homeostasis and disease. In recent years the development of genetically modified animals and new drugs targeting eicosanoids producing enzymes and receptors has unveiled new roles for eicosanoids in kidney function. This review provides an overview of eicosanoid biosynthesis and receptors and discusses recent findings on their role in acute and chronic renal diseases and in renal transplantation. Products of the cyclooxygenases, 5-lipoxygenase, and cytochrome P450 pathways of arachidonic acid metabolism act through distinct receptors presented at different segment of the nephron. Apart from its role in renal physiology and hemodynamic, eicosanoids actively participate in the pathogenesis of acute and chronic renal diseases and have immunoregulatory role in kidney transplantation. The new discoveries on the role of eicosanoids in kidney functions and the development of drugs targeting eicosanoids synthesis or action should help to envisage novel therapeutic approaches for patients suffering from renal diseases.

  7. Avances en nuevos marcadores de daño renal en el diagnóstico y tratamiento de la leishmaniosis canina

    OpenAIRE

    Guerrero Cabrera, Samantha

    2017-01-01

    La leishmaniosis canina (CanL, canine leishmaniosis) es una zoonosis endémica transmitida por vectores. La enfermedad renal es una de las principales complicaciones y causas de mortalidad en la CanL. En la leishmaniosis humana se ha observado disfunción renal tubular asociada con defectos en la concentración de orina y con desequilibrios electrolíticos. Las pruebas de laboratorio comúnmente utilizadas para evaluar la función renal carecen de una adecuada sensibilidad y especificidad, ...

  8. Ruptura do excretor renal: um caso atípico: apresentação de caso clínico

    OpenAIRE

    Graça, B; Coelho, M; Carrasquinho, J; Lourenço, M

    2006-01-01

    A ruptura espontânea do excretor renal é uma complicação pouco frequente da uropatia obstrutiva. A maioria das rupturas está associada a obstrução litiásica ureteral ou da junção pieloureteral, existindo geralmente um quadro clínico prévio de cólica renal ou litíase conhecida. A ruptura espontânea do excretor renal complicada é suspeitada clinicamente e o diagnóstico obtido por exames auxiliares, especialmente de imagiologia. Apresentamos o caso clínico de uma doente com ruptura espo...

  9. Contrast agents and renal cell apoptosis

    OpenAIRE

    Romano, Giulia

    2008-01-01

    Contrast media (CM) induce a direct toxic effect on renal tubular cells. This toxic effect may have a role in the pathophysiology of contrast nephropathy. I evaluated: (i) the cytotoxicity of CM [both low-osmolality (LOCM) and iso-osmolality (IOCM)], of iodine alone,and of an hyperosmolar solution (mannitol 8%) on human embryonic kidney (HEK 293), porcine proximal renal tubular (LLC-PK1), and canine Madin–Darby distal tubular renal (MDCK) cells; and (ii) the effectiveness of vario...

  10. Drug Dosing During Continuous Renal Replacement Therapies

    OpenAIRE

    Thompson, A. Jill

    2008-01-01

    Continuous renal replacement therapies (CRRT) are used to manage fluid overload and/or renal failure. The continuous nature of the fluid and solute removal has less impact on hemodynamic variables in critically ill patients, making CRRT preferred over intermittent hemodialysis for some patients in the intensive care arena. The impact of CRRT on drug removal is variable depending on the CRRT modality, the ultrafiltrate and dialysate flow rates, the filter, and the patient's residual renal func...

  11. [Hereditary cerebro-oculo-renal syndromes].

    Science.gov (United States)

    Sessa, Galina; Hjortshøj, Tina Duelund; Egfjord, Martin

    2014-02-17

    Although many congenital diseases present disturbances of the central nervous system, eyes and renal function, only few of these have a defined genetic basis. The first clinical features of cerebro-oculo-renal diseases usually develop in early childhood and deterioration of kidney function and even end-stage kidney disease may occur in a young age. The syndromes should be considered in patients with retarded growth and development, central nervous system abnormalities, impaired vision or blindness and progressive renal failure.

  12. Ultrasonography Renal Length Determination in Argentine Adults.

    OpenAIRE

    Bratti, Griselda Irina; Romano Barrera, Federico Exequiel; Mileo, Federico Gastón; Invernoz, Yamil; Gómez, César; Bendersky, Mariana

    2012-01-01

    The estimation of renal size is an important parameter in clinical evaluation and management of adult patients with renal disease. The maximum longitudinal diameter (MLD) of both kidneys may be influenced by height, age, sex and body mass index without expressing change in glomerular filtration rate. However, changes in renal size between examinations may be a suggestive evidence of disease, thus highly specific parameters are needed for understand this differences. The absence of an adult re...

  13. Renal collecting duct carcinoma: Report of a case with unusual imaging findings regarding renal function

    Directory of Open Access Journals (Sweden)

    Longwang Wang

    2013-01-01

    Full Text Available Renal collecting duct carcinoma (CDC is a rare and aggressive type of renal cell cancer (RCC, which is difficult to confirm before surgery. We present a case of CDC presenting a hypovascular mass on renal CTA and deteriorated renal function of the affected kidney on single photon emission computed tomography (SPECT, which are different from the most common RCC, clear cell RCC. Considering these findings, it would be worthwhile investigating the role of CTA and SPECT in CDC diagnosis.

  14. Ptose palpebral causada por Paquidermoperiostose

    Directory of Open Access Journals (Sweden)

    Patricia Regina de Pinho Tavares

    2014-08-01

    Full Text Available A paquidermoperiostose é uma síndrome caracterizada por acometimento cutâneo e ósseo, e em alguns casos ocorre comprometimento palpebral leve. É uma síndrome rara, idiopática ou hereditária, com provável herança autossômica dominante de penetrância variável. Descreve-se o caso de um paciente com ptose grave por paquidermoperiostose elucidando sua fisiopatologia e conduta cirúrgica aplicada.

  15. Colecistitis aguda por Streptococcus constellatus

    Directory of Open Access Journals (Sweden)

    M Sandra Gómez-Canosa

    2016-03-01

    Full Text Available Presentamos el caso de una paciente de edad avanzada y significativa comorbilidad que se diagnosticó de colecistitis aguda por Streptococcus constellatus. El drenaje de la vesícula biliar por colecistostomía percutánea, asociado a penicilinas, ha conseguido una evolución favorable. We report the case of a patient of advanced age and significant comorbidity diagnosed acute cholecystitis by Streptococcus constellatus. Gallbladder drainage by percutaneous cholecystostomy associated with penicillins has achieved a favorable outcome.

  16. Mortalidad intrahospitalaria por accidente cerebrovascular

    OpenAIRE

    Federico Rodríguez Lucci; Virginia Pujol Lereis; Sebastián Ameriso; Guillermo Povedano; MARÍA F DÍAZ; Alejandro Hlavnicka; Néstor A. Wainsztein; Ameriso, Sebastián F.

    2013-01-01

    La mortalidad global por accidente cerebrovascular (ACV) ha disminuido en las últimas tres décadas, probablemente debido a un mejor control de los factores de riesgo vascular. La mortalidad hospitalaria por ACV ha sido tradicionalmente estimada entre 6 y 14% en la mayoría de las series comunicadas. Sin embargo, los datos de ensayos clínicos recientes sugieren que esta cifra sería sustancialmente menor. Se revisaron datos de pacientes internados con diagnóstico de ACV del Banco de Datos de Str...

  17. Miasis cutanea por cordylobia anthropophaga

    OpenAIRE

    Alkorta Gurrutxaga Miriam; Beristain Rementeria Xabier; Cilla Eguiluz Gustavo; Tuneu Valls Anna; Zubizarreta Salvador José

    2001-01-01

    El incremento progresivo en el número de personas que viajan a países tropicales ha hecho que las enfermedades importadas adquieran una relevancia cada vez mayor. Las miasis (o infestaciones por larvas de moscas) cutáneas se encuentran entre este tipo de enfermedades siendo especialmente frecuentes en países tropicales. A propósito de la observación de un caso de miasis cutánea masiva por Cordylobia antropophaga, que ocurrió en una mujer de 34 años de edad al volver de un viaje a Senegal, se ...

  18. Hipoglucemia inducida por carcinoma adrenal

    OpenAIRE

    Jimena Soutelo; Melina Saban; Florencia Borghi Torzillo; Ruben Lutfi; Mariela Leal Reyna

    2013-01-01

    El carcinoma suprarrenal es una neoplasia maligna infrecuente y de mal pronóstico. La presentación clínica más común es originada por la producción hormonal excesiva, mientras que el desarrollo de hipoglucemia sintomática es excepcional. Presentamos el caso de una mujer de 37 años que ingresó al hospital por síntomas de hipoglucemias graves, hipertensión arterial, hipopotasemia y amenorrea secundaria. En el laboratorio se halló hipoglucemia con insulina inhibida y niveles de andrógenos en ran...

  19. Renal manifestations of rheumatic diseases. A review.

    Science.gov (United States)

    Horak, Pavel; Smrzova, Andrea; Krejci, Karel; Tichy, Tomas; Zadrazil, Josef; Skacelova, Martina

    2013-06-01

    Renal manifestations of rheumatic diaseases are sometimes very discrete and mild. At others, they can present the leading symptomatology of a given disease. Systemic lupus erythematosus, systemic scleroderma, renal vasculitis, rheumatoid arthritis, mixed connective tissue disease, Sjögren's syndrome and gout can all manifest in or be accompanied by renal impairment. The authors reviewed the literature on renal manifestation of rheumatic diseases using the key words, lupus erythematosus, systemic autoimmune diseases, rheumatoid arthritis, vasculitis and gout. The review below is accompanied by their own histological findings. Diagnosis requires proper interpretation of the clinical situation, laboratory results and image analysis methods plus close interdisciplinary collaboration between nephrologist and clinical pathologist/nephropathologist.

  20. Renal angiography with iohexol and metrizoate

    Energy Technology Data Exchange (ETDEWEB)

    Toernquist, C.; Holtaes, S.

    1984-02-01

    The nephrotoxicity of the ionic contrast medium metrizoate was compared with that of nonionic iohexol when used for renal angiography. Fifteen patients who underwent renal angiography with metrizoate and 15 with iohexol were studied. Serum creatinine level, Cr-51-EDTA clearance, and urine albumin level were recorded before and after angiography. Metrizoate affected renal function, as indicated both by a transient decrease in glomerular filtration rate and by a transient albuminuria. Renal function was unaffected by iohexol. Furthermore, iohexol produced less subjective discomfort than metrizoate. There appeared to be no difference in the quality of the angiograms obtained with the two media.