WorldWideScience

Sample records for ren zhong feng

  1. jinping feng

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. JINPING FENG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 671-681 Article. MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 · LIANG BAO LEI LV JINPING FENG ...

  2. Hai-Feng Cheng

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Hai-Feng Cheng. Articles written in Bulletin of Materials Science. Volume 37 Issue 1 February 2014 pp 127-132. Investigation of thermoelectric SiC ceramics for energy harvesting applications on supersonic vehicles leading–edges · Xiao-Yi Han Jun Wang Hai-Feng Cheng.

  3. JIU-REN YIN

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. JIU-REN YIN. Articles written in Bulletin of Materials Science. Volume 40 Issue 6 October 2017 pp 1255-1261. Molecular dynamics study on the relaxation properties of bilayered graphene with defects · WEI ZHANG JIU-REN YIN PING ZHANG YAN-HUAI DING YONG J IANG.

  4. Feng shui viis elementi / Ann Tenno

    Index Scriptorium Estoniae

    Tenno, Ann, 1952-

    2003-01-01

    Feng shui õpetuse kohaselt on viie põhielemendi vahelised suhted vastastikku loovad või hävitavad ja elementide kasutamisel oma isikliku ruumi kujundamisel tuleb arvestada eelkõige elementide omavahelisi seoseid

  5. Pertimbangan Aspek Kejiwaan terhadap Feng Shui dalam Perancangan Interior

    OpenAIRE

    C. Indrani, Hedy

    2003-01-01

    The truth of applying feng shui in interior design is always doubted because feng shui is still consider mystically, unlogic, and unusual, therefore it needs facts of this potential feng shui. As knowledge, feng shui psychologically plays important role for home design that it increases psychological life of the residents.

  6. Lutter øren

    DEFF Research Database (Denmark)

    Bekker-Nielsen, Tønnes

    2003-01-01

    Ifølge den romerske forfatter Pomponius Mela levede der engang ved Vadehavet et folk, panotierne, med øren så store at de kunne slå dem omkring sig som værn mod kulden.......Ifølge den romerske forfatter Pomponius Mela levede der engang ved Vadehavet et folk, panotierne, med øren så store at de kunne slå dem omkring sig som værn mod kulden....

  7. Individual Differences in Zhong-Yong tendency and Processing Capacity

    Directory of Open Access Journals (Sweden)

    Ting-Yun eChang

    2014-11-01

    Full Text Available The present study investigated how an individual’s Zhong-Yong tendency is related to his/her perceptual processing capacity. In two experiments, participants completed a Zhong-Yong Thinking Style Scale and performed a redundant-target detection task. Processing capacity was assessed with a nonparametric approach (systems factorial technology, SFT and a parametric (linear ballistic accumulator model, LBA approach. Results converged to suggest a positive correlation between Zhong-Yong tendency and processing capacity. High middle-way thinkers had larger processing capacity in multiple-signal processing compared with low middle-way thinkers, indicating that they processed information more efficiently and in an integrated fashion. Zhong-Yong tendency positively correlates with the processing capacity. These findings suggest that the individual differences in processing capacity can account for the reasons why high middle-way thinkers tend to adopt a global and flexible processing strategy to deal with the external world. Furthermore, the influence of culturally dictated thinking style on cognition can be revealed in a perception task.

  8. Feng shui põhiprintsiibid - ajastamine / Ann Tenno

    Index Scriptorium Estoniae

    Tenno, Ann, 1952-

    2003-01-01

    Mida mõistetakse ajastamise all feng shui's. Feng shui abil endale soodsa elukoha leidmisel tuleb silmas pidada järgnevaid põhielemente: chi energia, mäed, vesi, tuul, maapind, suund ja orientatsioon ning ajastamine

  9. Weierstrass semigroups and the Feng-Rao Distance

    DEFF Research Database (Denmark)

    Campillo, Antonio; Farran, Ignacio

    2000-01-01

    We detrmine the Feng-Rao distance for several claases of codes from algebraic geometry usingthe weierstrass semigroups......We detrmine the Feng-Rao distance for several claases of codes from algebraic geometry usingthe weierstrass semigroups...

  10. Feng shui taevased olendid / Ann Tenno

    Index Scriptorium Estoniae

    Tenno, Ann, 1952-

    2003-01-01

    Traditsioonilise maastikukoolkonna feng shui sümboliteks on roheline draakon, valge tiiger, must kilpkonn, punane fööniks. Taevased olendid tähistavad eelkõige maastikuvorme, nende abil võib tähistada olemasolevaid ehitisi ja struktuure, mis ümbritsevad meie kodu

  11. Zhong-Yong as Dynamic Balancing Between Yin-Yang Opposites

    DEFF Research Database (Denmark)

    Li, Xin

    2018-01-01

    of Zhong-Yong balancing being incorrect and incomplete, the author proposes an alternative perspective on Zhong-Yong as dynamic balancing between Yin-Yang opposites. Design/methodology/approach: The author first explain why Peter P. Li’s “asymmetry” and “superiority” arguments are flawed by referring...... to the original text of the classical book of Zhong-Yong (中庸) and a comparison between Zhong-Yong and Aristotle’s doctrine of the mean. The author then propose an alternative approach to Zhong-Yong balancing that is embedded in the original text Zhong-Yong but somehow has been neglected by many Chinese scholars...

  12. ren Kierkegaard

    DEFF Research Database (Denmark)

    Klausen, Søren Harnow

    This book is a succinct guide to Søren Kierkegaard’s contribution to educational thought. Kierkegaard is not usually known as an educational thinker, but the book shows how his key notions and ideas are nevertheless highly relevant to educational theory and practice. It places them within...... the context of Kierkegaard’s philosophy and the philosophy of his time, while also exploring their significance to issues of contemporary concern, like the question of how far education should aim at fostering useful skills or support more ambitious goals. The central topics are Kierkegaard’s diagnosis...

  13. [The essence of Professor Wu Lian-Zhong's acupuncture manipulation].

    Science.gov (United States)

    Liu, Jing; Guo, Yi; Wu, Lian-Zhong

    2014-05-01

    The painless needle insertion technique, summarized by Professor WU Lian-zhong during his decades of acupuncture clinical practice is introduced in this article, which is characterized as soft, flexible, fast, plucking and activating antipathogenic qi. The Sancai (three layers) lifting and thrusting manipulation technique is adopted by Professor WU for getting the qi sensation. And features of 10 kinds of needling sensation such as soreness, numbness, heaviness, distension, pain, cold, hot, radiation, jumping and contracture are summarized. Finger force, amplitude, speed and time length are also taken as the basis of reinforcing and reducing manipulations. Moreover, examples are also given to explain the needling technique on some specific points which further embodies Professor WU's unique experiences and understandings on acupuncture.

  14. On the Feng-Rao bound for generalized hamming weights

    DEFF Research Database (Denmark)

    Geil, Hans Olav; Thommesen, Christian

    2006-01-01

    The Feng-Rao bound gives good estimates of the minimum distance of a large class of codes. In this work we are concerned with the problem of how to extend the Feng-Rao bound so that it deals with all the generalized Hamming weights. The problem was solved by Heijnen and Pellikaan in [7] for a large...... family of codes that includes the duals of one-point geometric Goppa codes and the q-ary Reed-Muller codes, but not the Feng-Rao improved such ones. We show that Heijnen and Pellikaan's results holds for the more general class of codes for which the traditional Feng-Rao bound can be applied. We also...... establish the connection to the Shibuya-Sakaniwa bound for generalized Hamming weights ([15], [16], [17], [18], [19] and [20]). More precisely we show that the Shibuya-Sakaniwa bound is a consequence of the extended Feng-Rao bound. In particular the extended Feng-Rao bound gives always at least as good...

  15. On the Feng-Rao bound for generalized Hamming weights

    DEFF Research Database (Denmark)

    Geil, Olav; Thommesen, Christian

    2005-01-01

    The Feng-Rao bound gives good estimates of the minimum distance of a large class of codes. In this work we are concerned with the problem of how to extend the Feng-Rao bound so that it deals with all the generalized Hamming weights. The problem was solved by Heijnen and Pellikaan in [7] for a large...... family of codes that includes the duals of one-point geometric Goppa codes and the q-ary Reed-Muller codes, but not the Feng-Rao improved such ones. We show that Heijnen and Pellikaan’s results holds for the more general class of codes for which the traditional Feng-Rao bound can be applied. We also...... establish the connection to the Shibuya-Sakaniwa bound for generalized Hamming weights ([15], [16], [17], [18], [19] and [20]). More precisely we show that the Shibuya-Sakaniwa bound is a consequence of the extended Feng-Rao bound. In particular the extended Feng-Rao bound gives always at least as good...

  16. Correspondence regarding Zhong et al., BMC Bioinformatics 2013 Mar 7;14:89.

    Science.gov (United States)

    Kuhn, Alexandre

    2014-11-28

    Computational expression deconvolution aims to estimate the contribution of individual cell populations to expression profiles measured in samples of heterogeneous composition. Zhong et al. recently proposed Digital Sorting Algorithm (BMC Bioinformatics 2013 Mar 7;14:89) and showed that they could accurately estimate population-specific expression levels and expression differences between two populations. They compared DSA with Population-Specific Expression Analysis (PSEA), a previous deconvolution method that we developed to detect expression changes occurring within the same population between two conditions (e.g. disease versus non-disease). However, Zhong et al. compared PSEA-derived specific expression levels across different cell populations. Specific expression levels obtained with PSEA cannot be directly compared across different populations as they are on a relative scale. They are accurate as we demonstrate by deconvolving the same dataset used by Zhong et al. and, importantly, allow for comparison of population-specific expression across conditions.

  17. Keeping Current: Feng Shui and the School Library Media Specialist.

    Science.gov (United States)

    Barron, Daniel D.

    2000-01-01

    Discusses the changing shift in education, including learning resources centers, from a production to a consumer mind-set, focusing on the activity of learning rather than teaching. Highlights include learning communities; personal mastery; developing a vision; the interconnectedness of organizations; harmony and balance, similar to feng shui; and…

  18. Eestimaine feng shui talus ja mõisas / Kadi Lehtmets

    Index Scriptorium Estoniae

    Lehtmets, Kadi

    2006-01-01

    Geobioloogia ja feng shui asjatundjad Siret ja Janno Seeder on uurinud ja mõõtnud Eesti talukohtade ja mõisate energeetikat. Ilmneb, et on osatud end loodusenergiatega tasakaalu seada. S. ja J. Seederi nõuandeid uue maja ehitajaile

  19. Zhong et al., Afr J Tradit Complement Altern Med. (2014) 11(1):1-14

    African Journals Online (AJOL)

    cadewumi

    Yunqing Zhong*1, Xiufeng Wang2, Guanglan Xu,1, Bing Mao3, Wei Zhou3, Jie Min3, Hongli Jiang3, Xiang Diao4 , ..... due to COPD exacerbations, and 1 experienced a cerebrovascular accident. ..... the body (Makino T., 2005b; Hong et al., 2011). ... An, X., Zhang, A.L., Yang, A.W., Lin, L., Wu, D., Guo, X., Shergis, J.L., Thien, ...

  20. Research of composite mutagenesis on Soybean HeFeng25

    International Nuclear Information System (INIS)

    Zheng Wei; Guo Tai; Wang Zhixin; Wu Xiuhong; Li Candong; Liu Zhongtang; Zhang Maoming; Han Shifeng; Liu Yuhong

    2011-01-01

    On the research four main strains agronomic characters of M2 are analyzed, using space launch and gamma radiation 60 Co-γ composite process for the test materials Soybean HeFeng25. The results show that: the plant height, the first pod hight, number of node, number of plant pod and seed were significant or highly significantlevel. There were only one strain has mutation rate. Other strains on number of node variation is not obvious. Plant hight, the first pod hight, number of plant pod, number of plant seed have different levels of mutation rate. It can be used for soybean breeding. (authors)

  1. Fast Erasure and Error decoding of Algebraic Geometry Codes up to the Feng-Rao Bound

    DEFF Research Database (Denmark)

    Jensen, Helge Elbrønd; Sakata, S.; Leonard, D.

    1996-01-01

    This paper gives an errata(that is erasure-and error-) decoding algorithm of one-point algebraic geometry codes up to the Feng-Rao designed minimum distance using Sakata's multidimensional generalization of the Berlekamp-massey algorithm and the votin procedure of Feng and Rao.......This paper gives an errata(that is erasure-and error-) decoding algorithm of one-point algebraic geometry codes up to the Feng-Rao designed minimum distance using Sakata's multidimensional generalization of the Berlekamp-massey algorithm and the votin procedure of Feng and Rao....

  2. Zhong-Yong as Dynamic Balancing Between Yin-Yang Opposites

    DEFF Research Database (Denmark)

    Li, Xin

    2017-01-01

    Purpose The purpose of this paper is to comment on Peter Ping Li’s understanding of Zhong-Yong balancing, presented in his article titled “Global implications of the indigenous epistemological system from the East: How to apply Yin-Yang balancing to paradox management.” Seeing his understanding....... Originality/value This commentary contributes to the “West meets East” discourse by debunking Peter P. Li’s assertion that Yin-Yang balancing is superior as a solution to paradox management and his prescription that balancing between Yin-Yang opposites must be asymmetric. It also contributes to the Chinese...

  3. The effect of 'Liang-Feng-Su' on increasing production of sweet potato

    International Nuclear Information System (INIS)

    Liu Yitong; Wang Zhifen

    1991-01-01

    Treating sweet potato seedling with 33 x 10 -6 'Liang-Feng-Su', by means of phosphorus-32 and carbon-14 tracing technique showed that the use of 'Liang-Feng-Su' not only increased the root vigor and net photosynthetic efficiency of leaves, but also promoted the transport of photosynthate to root tubers which results in economic benefit

  4. ren Kjørup

    DEFF Research Database (Denmark)

    2009-01-01

    Film om filosofi- og æstetikprofessoren Søren Kjørup om kunst og kommunikation, billeder og museer, semiotik og videnskabsteori, med optagelser fra hans mange virkefelter på Roskilde Universitet, i København, Norge og Paris. Fysisk medie: DVD-film med booklet ISAN: 978-87-992867-0-6...

  5. Nicholas Steno and Renè Descartes

    DEFF Research Database (Denmark)

    Olden-Jørgensen, Sebastian

    2009-01-01

    Den danske videnskabsmand Niels Steensen (1638-86) læste allerede som ung student Renè Descartes og blev grebet af hans metode, som han forblev tro i hele sit videnskabelige virke. Cartesianismen kan beskrives som Steensens videnskabelige paradigme (Kuhn), men det var også et paradigme, han testede...

  6. Experimental study of desulfurization of Zhong Liang Shau high sulfur coal by flotation

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Z.; Huang, B.; Cao, J. [China University of Mining and Technology (China). Beijing Graduate School

    1994-12-01

    Emission of large amount of SO{sub 2} from combustion of high sulfur coal causes serious environmental pollution. Pre-combustion desulfurization of high sulfur coal has become a necessity. This paper reports test results of fine coal desulfurization with different flotation technology and the effect of pyrite depressant. Test work showed that when the coal sample from Zhong Liang Shau was processed with a Free Jet Flotation Column its pyritic sulfur content was reduced from 3.08% to 0.84%, with 72.22% recovery of combustible matter in clean coal. The concept of Desulfurization Efficiency Index E{sub ds} for comprehensive evaluation of desulfurization process is proposed, which is defined as the product of the ratio of sulfur content reduction of clean coal and the recovery of combustible matters. 6 refs., 4 figs., 3 tabs.

  7. Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

    International Nuclear Information System (INIS)

    Jang, Jong Sik; Kim, Sung Ho

    2008-01-01

    The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients

  8. Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Jong Sik [Kyungpook National University, Daegu (Korea, Republic of); Kim, Sung Ho [Chonnam National University, Gwangju (Korea, Republic of)

    2008-09-15

    The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients.

  9. Association between Social Integration and Health among Internal Migrants in ZhongShan, China.

    Directory of Open Access Journals (Sweden)

    Yanwei Lin

    Full Text Available Internal migrants are the individuals who migrate between regions in one country. The number of internal migrants were estimated at 245 million in China in 2013. Results were inconsistent in the literature about the relationship between their health statuses and social integration. The main difference exists on how to measure the social integration and whether health statuses of internal migrants improve with years of residence. To complement the existing literature, this study measured social integration more comprehensively and estimated the internal migrants' health statuses with varying years of residence, and explored the associations between the migrants' social integration and health. We used the data from 2014 Internal Migrant Dynamic Monitoring Survey of Health and Family Planning in ZhongShan, China. Health status was measured from four aspects: self-reported health, subjective well-being, perception of stress, mental health. We measured social integration through four dimensions: economy, social communication, acculturation, and self-identity. The analyses used multiple linear regressions to examine the associations between self-reported health, subjective well-being, and perception of stress, mental health and social integration. The analytical sample included 1,999 households of the internal migrants and 1,997 local registered households, who were permanent residents in ZhongShan. Among the internal migrants, Adults in the labor force, who were aged 25 to 44 years old, accounted for 91.2% of the internal migrant population, while 74.6% of the registered population were in that age group. Median residential time among migrants was 2.8 (1.3-6.2 years, and 20.2% of them were migrating in the same Guangdong province. Except for mental health, other health statuses among migrants had significant differences compared with local registered population, e.g. self-reported health was better, but subjective well-being was worse. However, these

  10. Renæssancen i svøb

    DEFF Research Database (Denmark)

      Hvornår holder middelalderen op og afløses af renæssancen? Og kan det virkelig passe at renæssancen i Danmark først slår igennem 150 år efter den italienske? Disse spørgsmål mødtes en række forskere og specialister om og diskuterede i det danske renæssanceår 2006. Resultatet blev 13 nye bidrag ...

  11. Genoprotective effect of the Chinese herbal decoction xiao jian zhong tang.

    Science.gov (United States)

    Szeto, Yim-Tong; Cheng, Ngok-Fung; Pak, Sok-Cheon; Kalle, Wouter

    2013-03-01

    The Chinese herbal decoction formula Xiao Jian Zhong Tang (XJZT) is one of the classic formulas from the classic traditional Chinese medicine (TCM). Previous studies on XJZT found that it is effective for treating peptic ulcer, irritable bowel syndrome, functional gastroenteritis and similar psychosomatic disorders of the digestive organs. It has also been shown that all the herbs used in XJZT contain antioxidants. In this study, we investigated the in vitro DNA protection effect of the individual herb extracts and the whole formula. Water extract of the herbs and XJZT were used to pre-treat human lymphocytes. The lymphocytes were then exposed to hydrogen peroxide. The in vitro DNA protection effect of the herbs was investigated by comet assay. No DNA protective effect (P < 0.05) was found for individual herb extracts, but XJZT showed protection of human lymphocytic DNA upon oxidative stress (P < 0.05). The in vitro DNA protection effect of XJZT was conferred by the synergistic effect of the herbs, while the individual herbs had no such effect.

  12. ren Kierkegaard og blikkets koder

    DEFF Research Database (Denmark)

    Linnet, Ragni

    this in the work of the landscape painter J.L. Lundbye. Lundbye was keenly interested in Kierkegaard, which can be traced in the formal qualities of some of his paintings. The thesis also shows that Søren Kierkegaard has an independent and systematic pictorial theory that is based on such aspects as close...... kinship to music (and time as time) are screened off. Hegel's thesis of 'an art after art', i.e. the death of the idealistic, beautiful work and its resurrection in a prosaic pictorial expression in which the formal qualities are at the centre, is not incorporated in the Danish reception, so that Hegel...

  13. Isak Dinesen Reading Søren Kierkegaard

    DEFF Research Database (Denmark)

    Bunch, Mads

    Not only did Isak Dinesen (Karen Blixen, 1885-1962) read the works of her fellow-countryman, the Danish philosopher Søren Kierkegaard (1813-1855), closely, she also created a surprisingly large number of tales that critically engage Kierkegaard’s works. In this thorough comparative study, Mads Bu...... and develops from the early tale ‘Carnival’ (1926-27) to ‘The Dreamers’ (1934), ‘The Pearls’ (1942), ‘Babette’s Feast’ (1950) and her last tale ‘Ehrengard’ (1963). Bunch’s close readings reveal that Dinesen’s ironical counter-tales concerning Kierkegaard border at times on sheer parody....

  14. René Goupil: patron saint of anesthetists.

    Science.gov (United States)

    Quintal, J

    1995-06-01

    René Goupil, the patron saint of anesthetists, is addressed mainly as a 17th century French surgeon who practiced his art in North America. He is also presented as a Jesuit martyr and saint. The article freely borrows from past writings of Jesuits on René Goupil.

  15. ren Buus. Thirty years of psychoacoustic inspiration

    DEFF Research Database (Denmark)

    Poulsen, Torben

    2005-01-01

    ren Buus did his MSc at the Acoustics Laboratory, Technical University of Denmark (DTU), in 1975 on the topic headphone calibration. He showed the importance of reliable reference values for psychoacoustic research and Søren was a great inspiration for my work (Scand. Audiol. 20, 205–207 (1991...

  16. snerti lEhissip tion flux me surements over south f y of feng l during ...

    Indian Academy of Sciences (India)

    his p per des ri es me surement of irEse p r meters nd estim tion of sensi le nd l tent he t fluxes y the snerti lEhissip tion99 te hnique over south f y of feng lF he d t were olle ted on. y g r u ny during fyfwi E ilot ruise during the period PQrd y to er IWWV to IPth xovem er. IWWV over south f y of feng lF he fluxes re estim ...

  17. Fast Erasure-and error decoding of algebraic geometry codes up to the Feng-Rao bound

    DEFF Research Database (Denmark)

    Høholdt, Tom; Jensen, Helge Elbrønd; Sakata, Shojiro

    1998-01-01

    This correspondence gives an errata (that is erasure-and error-) decoding algorithm of one-point algebraic-geometry codes up to the Feng-Rao designed minimum distance using Sakata's multidimensional generalization of the Berlekamp-Massey algorithm and the voting procedure of Feng and Rao....

  18. Feng shui väärtus on vaimujõus / Marika Tomberg ; komment. Lea Eermann, komment. Rein Weber

    Index Scriptorium Estoniae

    Tomberg, Marika

    1999-01-01

    Feng shui järgi korraldatud Lea Eermanni kodust Nõmmel. Feng shui- ja geobioloogia-alase nõustamisega tegelev arhitekt Rein Weber keskkonna mõjust tervisele, magamistoast. Enda ja maja kaitsmisest halbade mõjude eest. 10 illustratsiooni

  19. Monuments on Gemiler Ada and Karacaören Ada

    OpenAIRE

    Masuda, Tomoyuki

    1995-01-01

    Contents : 1. Church I on Gemiler Ada, 2. Church II on Gemiler Ada, 3. Church III on Gemiler Ada, 4. Church IV on Gemiler Ada, 5. Basilica on Karacaören Ada, 6. Painted Tomb on Karacaören Ada, 7. The Baptistery and the Chronology of Construction of the Karacaören Ada Basilica Complex, 8. Ölüdeniz Beach Basilica, 9. Iskender Basilica on Ölüdeniz Lagoon, 10. Mustafa Basilica near Beştaş Cove.

  20. Initiation of the Bukadaban Feng Normal Fault and Implications for the Topographic Evolution of Northern Tibet

    Science.gov (United States)

    Niemi, N. A.; Chang, H.; Li, L.; Molnar, P. H.

    2017-12-01

    The Bukadaban Feng massif in northern Tibet forms the footwall of an east-west trending graben that is kinematically linked to the Kunlun fault. Extension across this graben accommodates left-lateral slip on the Kunlun fault, as evidenced by the 2001 Kunlun earthquake rupture. New geochronologic and thermochronologic data from Bukadaban Feng provide insight into the evolution of this normal fault system. The Bukadaban Feng massif is composed of two plutonic units, an eastern unit of dacitic composition and a western unit of rhyolitic composition. Sixty-five LA-ICP-MS zircon U-Pb age determinations on the rhyolitic unit reveal a range of ages from 873 - 6.3 Ma. CA-TIMS U-Pb zircon geochronology on the nine youngest of these zircons yields an emplacement age of 6.8 Ma. Twenty-seven LA-ICP-MS zircon U-Pb ages on the dacite range from 208 to 7.9 Ma. No coherent population of young zircons was observed, and CA-TIMS analysis was not performed. Zircon (U-Th)/He analysis on the dacite and rhyolite yield ages of 3.9 and 5.0 Ma, respectively, while apatite (U-Th-Sm)/He thermochronology on 5 samples collected from both units along the trace of the normal fault yield ages ranging from 1.4 - 2.6 Ma. The emplacement ages and compositions of plutonic rocks at Bukadaban Feng are consistent with the eruptive timing and geochemistry of silicic volcanic rocks in the graben (Zhang et al., 2012). Silicic magmatism is often associated with the onset of crustal extension, and the combination of plutonism and correlative silicic volcanism provides an indirect constraint on the initiation of this graben at 7 Ma. The distinct zircon (U-Pb) and (U-Th)/He ages indicates that the rocks presently exposed at Bukadaban Feng were emplaced at ambient temperatures in excess of 180°C. The zircon and apatite thermochronologic data require exhumation at rates of 1-2 mm/yr since the late Miocene. A 7 Ma initiation age for the Bukadaban Feng normal fault is consistent with both published estimates of

  1. René Turlay (1932-2002)

    CERN Multimedia

    2002-01-01

    René Turlay, one of the four discoverers of Charge Parity (CP) violation, died on 29 November 2002 after battling with serious illness for over a year. As a brilliant French physicist, he has left his mark on CERN where he took part in several major experiments and chaired the LEP Experiments Committee (LEPC). He spent almost all his career at the CEA in Saclay which he joined in 1957. His first work with the Saturne synchrotron concerned the study of p meson production in nucleon-nucleon collisions at 2.3 GeV. After gaining his doctorate, he went to Princeton in 1962 as a post-doc. He played a major role in the memorable experiment at Brookhaven's AGS accelerator where together with James Christenson, James Cronin and Val Fitch he discovered the CP violation phenomenon in weak interactions. This discovery gave Andrey Sakharov a key to explaining the predominance of matter over antimatter and sowed the seeds of the model of the three quark families. On returning to France at the end of 1964, he ...

  2. Effects of Gan Lian Yuping Feng powder on the antibody titers to ...

    African Journals Online (AJOL)

    The study was conducted in order to investigate the immuno-enhancing property of the Chinese herbal formula, Gan lian Yu ping feng powder. Three hundred and thirty six 45-day-old chicks were randomly divided into eight groups. The chicks in groups A, B, C were orally given 0.25 g/mL (low-)C0.5 g/mL (middle-) and 1.0 ...

  3. Du-Zhong (Eucommia ulmoides Oliv.) Cortex Extract Alleviates Lead Acetate-Induced Bone Loss in Rats.

    Science.gov (United States)

    Qi, Shanshan; Zheng, Hongxing; Chen, Chen; Jiang, Hai

    2018-05-09

    The purpose of this study was to evaluate the protective effect of Du-Zhong cortex extract (DZCE) on lead acetate-induced bone loss in rats. Forty female Sprague-Dawley rats were randomly divided into four groups: group I (control) was provided with distilled water. Group II (PbAc) received 500 ppm lead acetate in drinking water for 60 days. Group III (PbAc+DZCE) received 500 ppm lead acetate in drinking water, and given intragastric DZCE (100 mg/kg body weight) for 60 days. Group IV (DZCE) was given intragastric DZCE (100 mg/kg body weight) for 60 days. The bone mineral density, serum biochemical markers, bone histomorphology, and bone marrow adipocyte parameters were analyzed using dual-energy X-ray absorptiometry, biochemistry, histomorphometry, and histopathology, respectively. The results showed that the lumbar spine and femur bone mineral density was significantly decreased in PbAc group compared with the control (P  0.05, vs. control and DZCE group). Serum calcium and serum phosphorus in the PbAc+DZCE group were greater than that in the PbAc group (P control group (P control, and DZCE groups (P > 0.05). Serum OPG and OPG/RANKL ration were significantly higher in the PbAc+DZCE group than that in the PbAc group (P control group, but those were restored in the PbAc+DZCE groups. The bone marrow adipocyte number, percent adipocyte volume per tissue volume (AV/TV), and mean adipocyte diameter were significantly increased in the PbAc group compared to the control (P control group were not significant. The results above indicate that the Du-Zhong cortex extract has protective effects on both stimulation of bone formation and suppression of bone resorption in lead-exposed rats, therefore, Du-Zhong cortex extract has the potential to prevent or treat osteoporosis resulting from lead expose.

  4. Feng shui And Emotional Response in the Critical care Environment (FARCE) study.

    Science.gov (United States)

    Charles, R; Glover, S; Bauchmüller, K; Wood, D

    2017-12-01

    The aim of this study was to investigate the relationship between nursing staff emotions and their surrounding environment, using the ancient system of feng shui. Two orientations of critical care bed spaces (wind and water groups, respectively) were mapped using a western bagua. Energy or 'chi' scores for nine emotions were calculated based on the positive or negative flow of chi in each of the two groups. During a two-week period, nursing staff were allocated to work in a bed space in either the wind or water groups; nursing staff who were not allocated to a study bed space acted as a control group. Participating nursing staff completed a questionnaire, ranking nine emotional states and their overall inner harmony, using a 11-point chi scale. In total, 108 questionnaires were completed. Critical bed space orientation according to feng shui principles was not related to nurse-reported chi scores or inner harmony (p > 0.05 for all measurements). There was also poor correlation between the bagua-predicted and reported chi scores for both the wind and water groups (R 2  = 0.338 and 0.093, respectively). The use of feng shui to guide the layout of critical care bed spaces does not improve the emotional well-being of nursing staff. © 2017 The Association of Anaesthetists of Great Britain and Ireland.

  5. XU Jian-zhong (许建中)——An Outstanding Doctor of Integrative Medicine on Respiratory Diseases

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@Professor XU Jian-zhong was born in a family of traditional Chinese doctor in Beijing, August, 1930. His native place is Putian, Fujian Province. Prof. XU has engaged for more than 40 years in clinical medicine since he was graduated from Shanxi Medical University in 1954. From 1958 to 1961, he was released from work to attend the TCM Learning Class for Doctors of Western Medicine for 3 years and granted the first grade prize by the Ministry of Health at graduation. Since then, the integration of traditional Chinese and western medicine (TCM-WM) has been the cause he devoted himself to. Now, he is Chief Doctor in Xiyuan Hospital, China Academy of Traditional Chinese Medicine, visiting professor of postgraduate education Department of China Academy of TCM, and Director of Specialty Committee of Respiratory Diseases, Chinese Association of Integration of Traditional and Western Medicine (CAIM).

  6. Clinical study on the relationship between FENG syndrome and pituitary-adrenal axis hormones at the onset of acute cerebral infarction

    International Nuclear Information System (INIS)

    Guan Shaoxia; Chen Jianfei; Ma Yaling

    2002-01-01

    Objective: To find the relationship between FENG syndrome and pituitary-adrenal axis hormones (adrenocorticotropic hormone ACTH, corticosteroid CS) at the onset of acute cerebral infarction (ACI). Methods: Using the table of syndrome quantitative diagnosis formulated according to the experiences of apoplectic experts to score the patient at the onset for 151 cases, the patients were divided into two groups: those of FENG syndrome (score ≥ 7 n=77) and NON-FENG syndrome (score<7 n=74). Levels of plasma ACTH and CS in there two groups and 60 healthy subject were determined with RIA. Results: 1) The levels of plasma ACTH and CS in the FENG group were very significantly higher than those in the NON-FENG group (p<0.001); the same result existed between patients and healthy subjects (p<0.001). 2) Highly positive cor-relationship existed between the scores of 77 FENG syndrome cases and the levels of plasma ACTH (r=0.89, t=14.61); moderately positive cor-relationship existed between the scores of FENG syndrome cases and the levels of plasma CS (r=0.53, t=4.83). Conclusion: There is a positive cor-relationship between FENG syndrome and pituitary adrenal axis hormones (ACTH, CS), the levels of plasma ACTH and CS can be regarded as index to differentiate FENG syndrome from NON-FENG syndrome

  7. [Professor Feng Run-Shen's essential experience in penetration needling method].

    Science.gov (United States)

    Feng, Mu-Lan

    2009-04-01

    Professor Feng Run-Shen is engaged in medicine for more than 60 years. He pays attention to medical ethics and has perfect medical skill. He energetically advocates combination of acupuncture with medication and stresses the concept of viewing the situation as a whole in selection of acupoints and treatment, particularly, clinical application of point properties. Clinically, he is accomplished in penetration needling, for which one needle acts on two or more points, enlarging the range of needling sensation, so it has very good therapeutic effects on many diseases. In the paper, the case samples about penetration needling in his clinical practice are summarized and introduced.

  8. ETV ekraanigraafika on Euroopa parimate seas / René Vilbre

    Index Scriptorium Estoniae

    Vilbre, René, 1970-

    2011-01-01

    Euroopa avalik-õiguslikle telejaamade konkurentsis valiti ETV ekraanigraafika viie parima hulka. Finaali pääses ETV kahes kategoorias - "Best design package" ja "Best use of audio". Intervjuu vaheklippide autori René Vilbrega. Võttemeeskonda kuulusid veel toimetaja Anu Välba, operaatorid Kristjan-Jaak Nuudi ja Ergo Treier

  9. René Sand (Belgium, President 1946 – 1953

    Directory of Open Access Journals (Sweden)

    2008-07-01

    Full Text Available The extraordinary significance of the life and work of René Sand lies in his central position as a mediator, promoter and coordinator of social work on an increasingly international level during the interwar-period and it can hardly be overestimated.

  10. "Darkness Overcomes You": Shaun Tan and Søren Kierkegaard

    Science.gov (United States)

    Johansen, Martin Blok

    2015-01-01

    This article analyses Shaun Tan's picturebook "The Red Tree" using some of the central concepts of existentialism developed by the Danish philosopher Søren Kierkegaard. Kierkegaard argued that being a person entails a coming-to-be ["tilblivelse"], and for the person this coming-to-be manifests itself as a task. The task is to…

  11. Reduction in nerve root compression by the nucleus pulposus after Feng's Spinal Manipulation☆

    Science.gov (United States)

    Feng, Yu; Gao, Yan; Yang, Wendong; Feng, Tianyou

    2013-01-01

    Ninety-four patients with lumbar intervertebral disc herniation were enrolled in this study. Of these, 48 were treated with Feng's Spinal Manipulation, hot fomentation, and bed rest (treatment group). The remaining 46 patients were treated with hot fomentation and bed rest only (control group). After 3 weeks of treatment, clinical parameters including the angle of straight-leg raising, visual analogue scale pain score, and Japanese Orthopaedic Association score for low back pain were improved. The treatment group had significantly better improvement in scores than the control group. Magnetic resonance myelography three-dimensional reconstruction imaging of the vertebral canal demonstrated that filling of the compressed nerve root sleeve with cerebrospinal fluid increased significantly in the treatment group. The diameter of the nerve root sleeve was significantly larger in the treatment group than in the control group. However, the sagittal diameter index of the herniated nucleus pulposus and the angle between the nerve root sleeve and the thecal sac did not change significantly in either the treatment or control groups. The effectiveness of Feng's Spinal Manipulation for the treatment of symptoms associated with lumbar intervertebral disc herniation may be attributable to the relief of nerve root compression, without affecting the herniated nucleus pulposus or changing the morphology or position of the nerve root. PMID:25206408

  12. Main agronomic traits and resistance to rice blast of space-induced mutant lines of Zhong-er-ruan-zhan

    International Nuclear Information System (INIS)

    Xiao Wuming; Wang Hui; Liu Yongzhu; Guo Tao; Chen Zhiqiang; Yang Qiyun; Zhu Xiaoyuan

    2012-01-01

    The main agronomic traits and resistance to rice blast of 34 space-induced lines from an elite rice cultivar, Zhong-er-ruan-zhan were evaluated at their SP 4 . The resistance to blast of the mutant lines had been tested by two blast isolates previously. It was found that the mutant lines showed significant difference in plant height, effective panicles, panicle length and grains per panicle etc. from their parent. The range of variation in 1000-grain weight the largest, followed by the seed-setting rate, and that of effective panicles was the least among all the traits. Except for the line Z34, 33 mutant lines had broader resistance spectra than the wild-type based on the test with 38 different blast isolates, and all the 33 lines were also resistant to the panicle blast in the field. The result confirmed that selection for resistant to blast in lower generations was reliable. Taking account of agronomic traits and blast resistance, promising lines with resistance to blast and good agronomic characters could be selected from those mutant lines. Therefore, the elite rice germplasm with enhanced disease resistance can be produced. (authors)

  13. 冯梦龙的小说理论%Feng Menglong' s Novel Theory

    Institute of Scientific and Technical Information of China (English)

    傅承洲

    2012-01-01

    Feng Menglong composed three prefaces for his own novels San Yah. Though each preface focused on one question, they connected closely with and complemented each other, forming Feng's own novel theoretical system. The Prefaces of Ancient and Contemporary Novels first proposed the Popular Romance was originated in the art of speaking, compared to the Tang Dynasty folktales, the Popular Romance language to content are easy for or- dinary people to understand, and to accept and appreciate, playing a greater role in the society. The Preface of Jingshitongyaa explores the relationship between real life and artistic fiction, Feng used the fictional method that the figure does not have to experience such events, and such events do not have to happen to the figure. " Fiction should be composed to the rule that when event is real, the reason should not be pseudo; while the event is pseudo, the reason should also be. true. The story of the novel may be fictional, but historical novel should be based on strict historical facts. The "Preface of Xingshihengyan put forward the "theory of awakening the world," Feng Menglong bitterly felt the turbid and chaos of the late Ming Dynasty, he wanted to use the Popular Romance to alert the world to turn things around. To achieve the purpose of awakening the world, the popular fiction should be created with a good content, but also have to follow the laws of the novel.%冯梦龙为“三言”所作的三篇序,每篇重点论述一个问题,各篇又相互勾连补充,形成了自己的小说理论体系。《古今小说叙》首次提出通俗演义起源于说话艺术,与唐人传奇相比,通俗演义从语言到内容都通俗易懂,可以为普通百姓所接受和欣赏,发挥更大的社会作用。《警世通言叙》探讨了小说创作中生活真实与艺术虚构的关系问题,提出了“入不必有其事,事不必丽其人”的虚构方法,虚构要做到“事真而理不赝,即事赝而理亦

  14. Die politische Quacksalberei des libertären Paternalismus

    Directory of Open Access Journals (Sweden)

    Schramme Thomas

    2016-07-01

    Full Text Available Der libertäre Paternalismus befürwortet Eingriffe in die Entscheidungsfindung von Bürgern, ohne ihnen Optionen völlig nehmen zu wollen. Vielmehr soll die Lenkung des Willens durch Schubser (nudges geschehen. Im folgenden Beitrag möchte ich zeigen, dass der libertäre Paternalismus auf tönernen Füßen steht. Ich bediene mich dabei des polemischen Bilds von Quacksalbern. Dieses Bild passt zu meinem argumentativen Vorgehen, da ich erstens zeigen will, dass der libertäre Paternalismus falsche Diagnosen über vermeintliche Krankheiten der Willensbildung stellt, und zweitens, dass er die falsche Therapie empfiehlt. Im ersten Teil des Artikels kritisiere ich die Diagnose des libertären Paternalismus, wonach Menschen in ihrer Entscheidungsfindung systematisch fehlschlagen. Die Auswirkungen der zugrundeliegenden psychologischen Forschung werden missinterpretiert und damit vielen menschlichen Entscheidungen eine Art Defekt zugeschrieben. Der zweite Teil des Beitrags hinterfragt die Therapie des libertären Paternalismus. Für entsprechende Interventionen in die Wahlarchitektonik muss Wissen erlangt werden über die Richtung, in welche die Menschen jeweils geschubst werden sollten. Die hier genannte epistemische Aufgabe kann mit den theoretischen Mitteln des libertären Paternalismus nicht gelöst werden.

  15. Comparing the do's & taboos in Chinese Feng-Shui and Indian Vāstu-Shāstra architectural traditions

    NARCIS (Netherlands)

    Huang, En-Yu

    2012-01-01

    Chinese Feng-Shui and Indian Vāstu-Shāstra are two of the world’s best-known and longest-enduring systems of geomancy which have, for centuries, informed architectural practice of their respective cultural spheres. Albeit developed in different geo-cultural contexts and reinforced by their distinct

  16. On an integrable deformed affinsphären equation. A reciprocal gasdynamic connection

    International Nuclear Information System (INIS)

    Rogers, C.; Huang, Yehui

    2012-01-01

    The integrable affinsphären equation originally arose in a geometric context but has an interesting gasdynamic connection. Here, an integrable deformed version of the affinsphären equation is derived in a novel manner via the action of reciprocal transformations on a related anisentropic gasdynamics system. A linear representation for the deformed affinsphären equation is constructed by means of the reciprocal transformations. The latter are then employed to derive a class of exact solutions in parametric form. -- Highlights: ► A deformed affinsphären equation is derived via a reciprocal transformation. ► A linear representation for the deformed affinsphären equation is constructed. ► A class of exact solutions of the deformed affinsphären equation is presented.

  17. Farvel til glødepæren - goddag til...?

    DEFF Research Database (Denmark)

    Bülow, Katja

    2009-01-01

    Glødepæren er, som vi kender den, er hastigt på vej ud af markedet idet EU har vedtaget at udfase glødepæren inden udgangen af 2012. Og det er godt, for glødepæren er en energiforbrugende lyskilde, der foranlediger tonsvis af CO2 udledning til atmosfæren. Spørgsmålet er så hvilken lyskilde der ka...... spørgsmål om at kaste sig ud i helt nye og uopdagede løsningsmodeller?...

  18. Anoressia e mimesi secondo René Girard

    Directory of Open Access Journals (Sweden)

    Rosa Sidella

    2011-01-01

    Full Text Available Anorexia and Mimesis in René Girard’s Thought - One of the basic premises of Girard’s thought is the theory of mimetic desire, for which, in all human relationships, the Other as a model is perceived as a rival. Mimesis is also found in narcissism, in love relationships and eating disorders, such as anorexia and bulimia, which cannot and should not be classified only in psychoanalytic terms. In fact, we should in such cases consider cultural and social contexts, which also impose prescriptions about the care and appearance of the body.

  19. [René Allendy and the medicine of the imponderables].

    Science.gov (United States)

    Hochmann, J

    1993-01-01

    René Allendy was one of the first French psychoanalysts. He was also a homeopath. A text by him on the "medicine of the imponderables" demonstrates his proximity to esoteric theories. The objective of this article is to illustrate a cultural misunderstanding at the time of the introduction of psychoanalysis in France, when it met up with a Gnostic and Illuminist heritage that was still very much alive. This initial confusion between the Freudian approach, which was in keeping with the thinking of the Lumières, and a certain obscurantism, explains perhaps some of the resistance as well as some of the subsequent deviations of psychoanalysis in France.

  20. Inhibitory effect of bofutsushosan (fang feng tong sheng san) on glucose transporter 5 function in vitro.

    Science.gov (United States)

    Gao, Shengli; Satsu, Hideo; Makino, Toshiaki

    2018-03-01

    Bofutsushosan (BTS; fang feng tong sheng san in Chinese) is a formula in traditional Japanese Kampo medicine and Chinese medicine comprising eighteen crude drugs, and is used to treat obesity and metabolic syndrome. Fructose is contained in refreshing beverages as high-fructose corn syrup, and is associated with obesity. Fructose is absorbed via glucose transporter 5 (GLUT5) in the intestine. Therefore, the inhibition of GLUT5 is considered to be a target of obesity drugs. We evaluated the inhibitory effects of BTS extract and its constituents on fructose uptake using Chinese hamster ovary K1 cells, i.e., cells stably expressing GLUT5. Boiled water extract of BTS significantly suppressed GLUT5 function in a concentration-dependent manner without cytotoxicities. Among 18 components of BTS, the boiled water extracts of the rhizome of Zingiber officinale, the root and rhizome of Saposhnikovia divaricata, and the root of Platycodon grandiflorum exhibited significant inhibitory effects on fructose uptake with IC 50 values of 314, 119 and 475 µg/ml, respectively. Among the constituents of the rhizome of Z. officinale extract, 6-gingerol significantly inhibited GLUT5 with an IC 50 value of 39 µM, while 6-shogaol exhibited a significant but weak inhibition on GLUT5 at 100 µM. One of the mechanisms of action of BTS may be the inhibition of fructose absorption in the intestine, and one of the active components of BTS is the rhizome of Z. officinale and 6-gingerol.

  1. Assimilation of Feng-Yun-3B satellite microwave humidity sounder data over land

    Science.gov (United States)

    Chen, Keyi; Bormann, Niels; English, Stephen; Zhu, Jiang

    2018-03-01

    The ECMWF has been assimilating Feng-Yun-3B (FY-3B) satellite microwave humidity sounder (MWHS) data over ocean in an operational forecasting system since 24 September 2014. It is more difficult, however, to assimilate microwave observations over land and sea ice than over the open ocean due to higher uncertainties in land surface temperature, surface emissivity and less effective cloud screening. We compare approaches in which the emissivity is retrieved dynamically from MWHS channel 1 [150 GHz (vertical polarization)] with the use of an evolving emissivity atlas from 89 GHz observations from the MWHS onboard NOAA and EUMETSAT satellites. The assimilation of the additional data over land improves the fit of short-range forecasts to other observations, notably ATMS (Advanced Technology Microwave Sounder) humidity channels, and the forecast impacts are mainly neutral to slightly positive over the first five days. The forecast impacts are better in boreal summer and the Southern Hemisphere. These results suggest that the techniques tested allow for effective assimilation of MWHS/FY-3B data over land.

  2. Vastu Shastra And Feng Shui The Ancient Sciences And Their Fusion In Context Of Indian Architecture

    Directory of Open Access Journals (Sweden)

    Sujata Saran

    2017-11-01

    Full Text Available About 30 present of modern buildings are suffering from sick building syndrome. The design of buildings according to ancient sciences like vastu shastra and Feng shui are efficient to resolve the problem of sick building syndrome by making the building physically and psychologically satisfactory. Both the sciences are based on five basic elements. Human body is also composed of five elements and above all the nature is made up five elements. Therefore there should be an inter-relationship between man building and universe. These sciences are capable of resolving the problem of sick building syndrome by incorporating five basic elements as a part of building like Ayurveda a field of medicine based on natural means to heal and maintain the sick body. Similarly Buildings should be designed as a union of physical and metaphysical aspects. The physical aspect is related to five basic elements. Elements made up of matter and matter is associated with different colour and each colour has its own energy in terms of its wavelength colour is also important element to balance the energies the chromo therapy is also a way to balance the energies of human body and buildings and the metaphysical aspect is related to cosmos.

  3. Monograph of Keçiören Municipality

    Directory of Open Access Journals (Sweden)

    Savaş Zafer Şahin

    2015-12-01

    Full Text Available In Turkey, urban administration can be defined from a judicial perspective as the bundle of powers vested in municipalities. It is known that throughout republican history, municipalities, using these powers, have differentiated themselves via their own internal dynamics in parallel to the evolution of public policy and changes in legislation. Yet, it is obvious that there are important gaps in understanding this differentiation taking into consideration the structural conditions of individual municipalities. In particular, in order to thoroughly understand municipalities, it is important to consider periodical pictures of how each municipality has been affected by waves of decentralization and centralization experienced over the last thirty years. In this respect, this monograph, using the same monographic approach developed for the Çankaya Municipality, provides a picture of the existing situation of Ankara’s Keçiören Municipality and presents related problems and potential. This monograph, based on qualitative and quantitative research, presents a holistic evaluation of Keçiören Municipality in terms of its external environment, provision of services, decision-making processes, use of technology and communications.

  4. Discussion of FAN Zhong-yan’s Buddhist Thought and Personality Spirit%论范仲淹的佛禅思想及其人格精神

    Institute of Scientific and Technical Information of China (English)

    邢爽; 胡遂

    2014-01-01

    FAN Zhong-yan’s life ambition is to make the monarch as wise as Yao and Shun.He begged the ancient heart of Habitat for Humanity in his “YueYang Tower Notes”,“not pleased,not to have com-passion,”the implication was obvious Buddhist ideas with.The fusion of Confucianism and Buddhism thought of Fan Zhong-yan for the later generations to establish the “independent personality model un-moved either by gain or loss”.His life is spent in the pursuit and practice of Mahayana Bodhisattva “the highest state of compassion for the world of vision”,“being and not being”in perfect unity.%范仲淹的一生志在致君尧舜。《岳阳楼记》中他“尝求古仁人之心”,“不以物喜,不以己悲”的思想俨然带有佛家的意味。融合儒释思想的范仲淹为后来的士人树立了“宠辱不惊”的独立人格典范。他的一生都在追求和践行大乘菩萨道“悲心宏愿”的最高境界,为世人诠释了“有无之境”的完美统一。

  5. Feng Youlan’s Interpretation of Western Philosophy:A Critical Examination from the Perspective of Metaphysical Methodology

    Directory of Open Access Journals (Sweden)

    Derong Chen

    2015-04-01

    Full Text Available The paper aims to display a limited observation of Feng’s interpretation of Western philosophy through the window of metaphysical methodology. This paper concentrates on Feng’s interpretation of Western philosophy from the perspective of metaphysical methodology and aims to display a limited observation of Feng’s interpretation of Western philosophy through the window of metaphysical methodology. Based on a brief review the recent studies of Feng Youlan and Western philosophy, this paper analyzes the progress and insufficient aspects in current studies on this issue and particularly clarifies what are the metaphysics and metaphysical methods in the context of Feng Youlan’s philosophy. In clarifying Feng’s interpretation of Western philosophy from the perspective of methodology, this paper further critically analyzes the Feng’s positive metaphysical methods and negative metaphysical methods, and assumes that Feng’s negative metaphysical methods essentially is a kind of attitudes towards metaphysics but neither a kind of metaphysics nor a kind of metaphysical methods. Instead of characterizing metaphysical methods as positive and negative as Feng did, this paper suggests an alternative division of metaphysical methods: direct and indirect methods of dealing with metaphysical issues.

  6. René Wellek a Pražská škola

    Czech Academy of Sciences Publication Activity Database

    Sládek, Ondřej

    2016-01-01

    Roč. 1, č. 1 (2016), s. 19-30 ISSN 2453-8507 Institutional support: RVO:68378068 Keywords : literary theory ; structuralism ; poetics ; Wellek, René ; Prague School * structuralism * poetics * Wellek, René * Prague School * Prague linguistic circle * Mukařovský, Jan Subject RIV: AJ - Letters, Mass-media, Audiovision

  7. Identification of two novel powdery mildew resistance loci, Ren6 and Ren7, from the wild Chinese grape species Vitis piasezkii.

    Science.gov (United States)

    Pap, Dániel; Riaz, Summaira; Dry, Ian B; Jermakow, Angelica; Tenscher, Alan C; Cantu, Dario; Oláh, Róbert; Walker, M Andrew

    2016-07-29

    Grapevine powdery mildew Erysiphe necator is a major fungal disease in all grape growing countries worldwide. Breeding for resistance to this disease is crucial to avoid extensive fungicide applications that are costly, labor intensive and may have detrimental effects on the environment. In the past decade, Chinese Vitis species have attracted attention from grape breeders because of their strong resistance to powdery mildew and their lack of negative fruit quality attributes that are often present in resistant North American species. In this study, we investigated powdery mildew resistance in multiple accessions of the Chinese species Vitis piasezkii that were collected during the 1980 Sino-American botanical expedition to the western Hubei province of China. A framework genetic map was developed using simple sequence repeat markers in 277 seedlings of an F1 mapping population arising from a cross of the powdery mildew susceptible Vitis vinifera selection F2-35 and a resistant accession of V. piasezkii DVIT2027. Quantitative trait locus analyses identified two major powdery mildew resistance loci on chromosome 9 (Ren6) and chromosome 19 (Ren7) explaining 74.8 % of the cumulative phenotypic variation. The quantitative trait locus analysis for each locus, in the absence of the other, explained 95.4 % phenotypic variation for Ren6, while Ren7 accounted for 71.9 % of the phenotypic variation. Screening of an additional 259 seedlings of the F1 population and 910 seedlings from four pseudo-backcross populations with SSR markers defined regions of 22 kb and 330 kb for Ren6 and Ren7 in the V. vinifera PN40024 (12X) genome sequence, respectively. Both R loci operate post-penetration through the induction of programmed cell death, but vary significantly in the speed of response and degree of resistance; Ren6 confers complete resistance whereas Ren7 confers partial resistance to the disease with reduced colony size. A comparison of the kinetics of induction of powdery

  8. René Girard, Le bouc émissaire

    OpenAIRE

    Pailler, Jean-Marie

    2017-01-01

    René Girard est mort le 4 novembre 2015. Un retirage d’une de ses œuvres majeures, Le bouc émissaire, publiée en 1982, a eu lieu vers la fin de ce même mois. Ce retirage d’opportunité nécrologique allait, hélas, s’avérer plus opportun encore que prévu. Entre-temps s’était produite la tuerie du Bataclan, le 13 novembre. Cet événement et la chaîne de ceux qui ont suivi se prêtent à plusieurs lectures. L’une des plus suggestives – et des moins rassurantes – est celle qui fait appel aux rivalités...

  9. Historical Perspectives on Erklären and Verstehen: Introduction

    Science.gov (United States)

    Feest, Uljana

    The conceptual dichotomy of Erklären and Verstehen (explaining vs. understanding) has a revealing dual status. On the one hand, it has something of an antiquated air to it, as we loosely associate its origins with the work of Wilhelm Dilthey and other nineteenth-century German philosophers who are not widely read any more, at least not within contemporary Anglo-American history and philosophy of the human sciences. At the same time, however, remnants of the dichotomy still come up in various guises and in various areas of contemporary philosophy and philosophy of science. One example is the long-standing debate over the logical status of action explanations ("reasons vs. causes") in philosophy of mind (Davidson 1980), and associated issues of "teleological explanations" and the explanatory status of laws of nature in the philosophy of the human sciences (Dray 1957; Hempel 1965; von Wright 1971). Another is the question of whether the subject matter of the social sciences requires a special type of interpretative, hermeneutic, or perhaps even empathetic, "access" (Collingwood 1946; Winch 1964; Taylor [1971] 1985). More recently, there has been renewed interest in the question of how to explicate our capacity to interpret another person's actions (see the recent suggestion that the "theory-theory" vs. "simulation theory" distinction is similar to some aspects of the Erklären/Verstehen distinction) (Kögler and Stueber 2000). And within mainstream analytical philosophy of the social sciences, one of the central topics has long been the question of whether social facts/events can be reduced to the explanations of the actions of individuals (e.g., Kincaid 1997), raising questions about the units at which explanatory and/or interpretive efforts ought to be directed. ("individualism" vs. "holism"). This question can be traced back to early twentieth-century debates in economics and other emerging social sciences (Udehn 2001).

  10. St. René: the Patron Saint of Anaesthetists and a Patron Saint of Canada.

    Science.gov (United States)

    Calverley, R K

    1980-01-01

    René Goupil, the Patron Saint of Anaesthetists, and a Patron Saint of Canada, was born in Angers, France in 1608 and studied surgery. He joined the Jesuits as a donné or volunteer worker in 1640 and served in the then tiny colony of Quebec as one of the first medical workers of Canada. After earning meritorious praise for his skills, he again volunteered to attend the Hurons at Sainte Marie, a mission far beyond the frontiers. René's canoe party was ambushed. He was captured by the Mohawks and endured eight weeks of cruel torture before being killed on September 29, 1642. René was the first of eight North American martyrs whose dedication was recognized by canonization in 1930. St. René was appointed Patron Saint of Anaesthetists in 1951.

  11. [An exceptional human relationship (Michael P. Kierkegaard, Søren Kierkegaard)].

    Science.gov (United States)

    Jacobs, R

    1978-01-01

    There were a father and a son, Michael and Sören Kierkegaard, both highly talented, imaginitive, witty, humorous, especially interested in shrewd dialectrical dialogues respectively debates, both profound melancholy ponderers. But according to very own individuality their congeniality wasn't absolute. The father, being under a questionable rigorous opinion of sin, suffered from undeserved divine grace since early childhood. And Michael Kierkegaard made Sören anxious with the religious experience of original sin. This anxiety moved (touched or affected) the sensitive son mighty. Nevertheless he should not despair hopelessly like his unlucky father. On the contrary: Sørens incomparable melancholy, mental agony and anxiety (fear or anguish) forced the faith, existing independently of them, in a radical refining. That is why Sören Kierkegaard succeeded in sublimation of all psychological and philosophic (al) attitudes (or opinions) in the sphere of religiousness. And the result? A novel philosophy of life: Christian existentialism.

  12. Pekon palvonta René Girardin uskontoteorian valossa / Tuukka Sandström

    Index Scriptorium Estoniae

    Sandström, Tuukka

    2005-01-01

    Prantsuse filosoofi René Girardi ideedest primitiivse religiooni kohta. Setumaal veel 20. sajandi alguses levinud viljakusjumal Peko kultusest ja iga-aastasest uue Peko papi valimise rituaalist R. Girardi tõlgenduse valguses

  13. Dr.Zhang Ren's Experience in Acupuncture Treatment of Obstinate Eye Diseases

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Dr.Zhang Ren (張仁), the board chairman of Shanghai Acupuncture Association, has been engaging in acupuncture treatment for more than 30years, during which he has kept on exploring the acupuncture therapies for obstinate diseases,especially for the obstinate eye diseases, ant summed up rich experience in this aspect. The following is a summary of what the author has learned from Dr. Zhang Ren.

  14. The avant-garde is not dead / René Block ; intervjueerinud Eero Epner

    Index Scriptorium Estoniae

    Block, René, 1942-

    2010-01-01

    Intervjuu saksa galeristi ja kuraatori René Blockiga, kes 1964. a. avas Berliinis galerii, kus eksponeeris J. Beuysi, S. Polke, G. Richteri jt. töid. Töötamisest kuraatorina alates 1970. aastatest, biennaalide tulevikust, avangardist. René Blocki galeriis 1966. a. toimunud Joseph Beuys'i performance'ist "Kuidas seletada kunsti surnud jänesele", millest inspireerituna teater NO99 lõi samanimelise lavastuse

  15. Dialyzer reuse following manual reprocessing with a new sterilant, RenNew-D.

    Science.gov (United States)

    Gagnon, R; Adkar, V; Kaye, M

    1987-04-01

    Dialysis patients are at risk for toxicity from formaldehyde used in the reprocessing of dialyzers for reuse; therefore, replacing formaldehyde as a dialyzer sterilant would be advantageous. The potential for RenNew-D as a sterilizing agent was investigated in seven stable in-center hemodialysis patients over 20 consecutive dialyses with cuprammonium cellulose hollow-fiber dialyzers. Treatment with RenNew-D showed no toxicity to patients or dialyzers except for two blood leaks occurring in one patient. The mean number of dialyzer uses was 4.9. In all the dialyzers that passed functional testing small solute clearances were maintained with reuse. The ability of RenNew-D to improve the biocompatibility of reused dialyzers was documented with mean neutrophil counts falling to only 78% of initial values during first reuse of dialyzers processed with RenNew-D compared with a decrease in neutrophil count to 2% of initial values during first use of the same dialyzers. Our results suggest that RenNew-D may be a useful alternative to formaldehyde for the purpose of dialyzer reuse. A reuse procedure that includes processing with RenNew-D is associated with improved biocompatibility, possibly because of maintenance of the blood-derived membrane coating established during prior dialysis.

  16. Algorithm and assessment work of active fire detection based on FengYun-3C/VIRR

    Science.gov (United States)

    Lin, Z.; Chen, F.

    2017-12-01

    The wildfire is one of the most destructive and uncontrollable disasters and causes huge environmental, ecological, social effects. To better serve scientific research and practical fire management, an algorithm and corresponding validation work of active fire detection based on FengYun-3C/VIRR data, which is an optical sensor onboard the Chinese polar-orbiting meteorological sun-synchronous satellite, is hereby introduced. While the main structure heritages the `contextual algorithm', some new concepts including `infrared channel slope' are introduced for better adaptions to different situations. The validation work contains three parts: 1) comparing with the current FengYun-3C fire product GFR; 2) comparing with MODIS fire products; 3) comparing with Landsat series data. Study areas are selected from different places all over the world from 2014 to 2016. The results showed great improvement on GFR files on accuracy of both positioning and detection rate. In most study areas, the results match well with MODIS products and Landsat series data (with over 85% match degree) despite the differences in imaging time. However, detection rates and match degrees in Africa and South-east Asia are not satisfied (around 70%), where the occurrences of numerous small fire events and corresponding smokes may strongly affect the results of the algorithm. This is our future research direction and one of the main improvements requires achieving.

  17. Feng Yuxiang and Korean Independence Movement%冯玉祥与韩国独立运动

    Institute of Scientific and Technical Information of China (English)

    甘露

    2012-01-01

    冯玉祥作为中国近代史上著名的反帝爱国将军,对中国境内的韩国反日独立运动也给予了不少关注与支持。他在革命生涯早期就与韩国独立运动人士建立了联系,在抗战时期又大力支持韩国临时政府及各党派的工作,还积极参与中韩文化协会和韩侨基督教会的活动,为韩国独立运动和中韩友谊都作出了不可磨灭的贡献。%As an anti-imperialist and patriot in Chinese modem history, general Feng Yuxiang also gave his considerations and support to Korean independence movement in China. He established communication with Korean independence people early in his revolution career. During the Sino-Japanese War, he gave much support to Korean Provisional Government and different Korean parties, actively participate in Chinese-Korean Cultural Association and Korean YMCA's activities. General Feng Yuxiang made an indelible contribution to Korean independence movement and Chinese-Korean friendship.

  18. Did René Descartes Have Exploding Head Syndrome?

    Science.gov (United States)

    Otaiku, Abidemi Idowu

    2018-04-15

    René Descartes (1596-1650), "the Father of Modern Philosophy" and advocate of mind-body dualism, had three successive dreams on November 10, 1619 that changed the trajectory of his life and the trajectory of human thought. Descartes' influential dreams have been of interest to a number of commentators including the famous neurologist and psychoanalyst Sigmund Freud. Descartes' second dream in particular, in which he heard a loud noise in his head before seeing a bright flash of light upon awakening, has been discussed extensively. Commentators have employed psychoanalytic and medical explanations to account for Descartes' unusual nocturnal experience. In this tradition, I propose that Descartes' second dream was not a dream at all; rather, it was an episode of exploding head syndrome; a benign and relatively common parasomnia. I further suggest that Adrien Baillet's account of Descartes' experience constitutes the earliest description of exploding head syndrome, predating the account described by Silas Weir Mitchell in 1876 by nearly 200 years. © 2018 American Academy of Sleep Medicine.

  19. Refleksion - Worms kabinet og renæssancen

    DEFF Research Database (Denmark)

    Teglhus, Hanne

    2006-01-01

    Udstilling om Ole Worms liv og videnskab. Ole Worm var læge og videnskabsmand i renæssancen. Ud over at være medicinsk professor ved Københavns Universitet interesserede han sig indgående for Danmarks fortidsminder og runeskrift. Ole Worm skabte sit eget museum, det såkaldte  Museum Wormianum, som...... alt indhold. Ikke med originale genstande, men med dyr, sten, metal og artefakter, der kom så tæt på det originale som muligt.  Denne installation samt portrætgalleriet af Ole Worms forfædre og efterkommere udgør udstillingens hovedelementer. Dertil kommer eksempler på de naturobjekter, der indgik i hans...... medicinske behandlinger og et udvalg af Ole Worms originale videnskabelige publikationer. Til udstillingen er opbygget et moderne "skab dit eget museum" til brug for de besøgendes egne medbragte genstande, som de opfordres til at forsøge at systematisere og udstille efter behag....

  20. Influence of surface-normal ground acceleration on the initiation of the Jih-Feng-Erh-Shan landslide during the 1999 Chi-Chi, Taiwan, earthquake

    Science.gov (United States)

    Huang, C.-C.; Lee, Y.-H.; Liu, Huaibao P.; Keefer, D.K.; Jibson, R.W.

    2001-01-01

    The 1999 Chi-Chi, Taiwan, earthquake triggered numerous landslides throughout a large area in the Central Range, to the east, southeast, and south of the fault rupture. Among them are two large rock avalanches, at Tsaoling and at Jih-Feng-Erh-Shan. At Jih-Feng-Erh-Shan, the entire thickness (30-50 m) of the Miocene Changhukeng Shale over an area of 1 km2 slid down its bedding plane for a distance of about 1 km. Initial movement of the landslide was nearly purely translational. We investigate the effect of surface-normal acceleration on the initiation of the Jih-Feng-Erh-Shan landslide using a block slide model. We show that this acceleration, currently not considered by dynamic slope-stability analysis methods, significantly influences the initiation of the landslide.

  1. Un ente innovativo di ricerca e di servizi per la informazione geospaziale: GIS Research Center della Feng-Chia University di Taiwan (GIS.FCU

    Directory of Open Access Journals (Sweden)

    Mauro Salvemini

    2012-04-01

    Full Text Available La storia di un Laboratorio GIS a Taiwan nato da un accordo tra Feng-Chia University e la Università di Roma “LaSapienza” oggi tra i primi nel mondo nel settore dell’informazione geospaziale per la ricerca nell’ambito dei testdell’interoperabilità. A body of research and innovative services for geospatial infor-mation: GIS Research Center of Feng-Chia University in Taiwan (GIS.FCU The story of a GIS laboratory in Taiwan born on an agreement between the Feng-Chia University and the University of Rome "La Sapienza" now among the first in the world in the field of information for research for geospatial application.

  2. Synthesis of ReN3 Thin Films by Magnetron Sputtering

    Directory of Open Access Journals (Sweden)

    G. Soto

    2014-01-01

    Full Text Available In this work ReNx films were prepared by reactive magnetron sputtering at room temperature and deposited on a silicon wafer. It was found that the diffractograms of the nitrogen-rich rhenium film are consistent with those produced by high-pressure high-temperature methods, under the assumption that the film is oriented on the substrate. Using density functional calculations it was found that the composition of this compound could be ReN3, instead of ReN2, as stated on previous works. The ReN3 compound fits in the Ama2 (40 orthorhombic space group, and due to the existence of N3 anions between Re layers it should be categorized as an azide. The material is exceptionally brittle and inherently unstable under indentation testing.

  3. Lactobacillus salivarius REN inhibits rat oral cancer induced by 4-nitroquioline 1-oxide.

    Science.gov (United States)

    Zhang, Ming; Wang, Fang; Jiang, Lu; Liu, Ruihai; Zhang, Lian; Lei, Xingen; Li, Jiyou; Jiang, Jingli; Guo, Huiyuan; Fang, Bing; Zhao, Liang; Ren, Fazheng

    2013-07-01

    Despite significant advances in cancer therapy, cancer-related mobility and mortality are still rising. Alternative strategies such as cancer prevention thus become essential. Probiotics represent an emerging option for cancer prevention, but studies are limited to colon cancers. The efficiency of probiotics in the prevention of other cancers and the correlative mechanism remains to be explored. A novel probiotics Lactobacillus salivarius REN (L. salivarius REN) was isolated from centenarians at Bama of China, which showed highly potent antigenotoxicity in an initial assay. 4-nitroquioline 1-oxide (4NQO)-induced oral cancer model was introduced to study the anticancer activity of L. salivarius REN in vivo. The results indicated that oral administration of probiotic L. salivarius REN or its secretions could effectively suppress 4NQO-induced oral carcinogenesis in the initial and postinitial stage, and the inhibition was in a dose-dependent manner. A significant decrease of neoplasm incidence (65%-0%) was detected in rats fed with the high dose of L. salivarius REN [5 × 10(10) CFU/kg body weight (bw)/d]. In vivo evidences indicated that the probiotics inhibited 4NQO-induced oral cancer by protecting DNA against oxidative damage and downregulating COX-2 expression. L. salivarius REN treatment significantly decreased the expression of proliferating cell nuclear antigen (PCNA) and induced apoptosis in a dose-dependent manner. Our findings suggest that probiotics may act as potential agents for oral cancer prevention. This is the first report showing the inhibitory effect of the probiotics on oral carcinogenesis. ©2013 AACR.

  4. Gemeinsame Gene für Hören, Sehen und Tastsinn

    OpenAIRE

    Gross, M; Lewin, G; Frenzel, H

    2012-01-01

    Hintergrund: Hören und Tastsinn sind zwei distinkte sensorische Systeme, die auf der Transformation mechanischer Kräfte in elektrische Signale basieren. Während für Hörstörungen mehrere einzelne Genmutationen bekannt sind, ist für den eingeschränkten Tastsinn bisher keine Mutation beschrieben. Hypothesen: Es gibt gemeinsame Gene für Hören und Tastsinn. Es lassen sich Hinweise auf einzelne Genmutationen konkretisieren.Material und Methoden: 3 prospektive Teilstudien: Zwillingsstudie zu Tas...

  5. Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.

    Science.gov (United States)

    Deng, Shan; Hu, Bing; An, Hong-Mei; Du, Qin; Xu, Ling; Shen, Ke-Ping; Shi, Xiu-Feng; Wei, Meng-Meng; Wu, Yang

    2013-06-08

    Colorectal cancer remains one of the leading causes of cancer death worldwide. Traditional Chinese Medicine (TCM) has played a positive role in colorectal cancer treatment. There is a great need to establish effective herbal formula for colorectal cancer treatment. Based on TCM principles and clinical practices, we have established an eight herbs composed formula for colorectal cancer treatment, which is Teng-Long-Bu-Zhong-Tang (TLBZT). We have demonstrated the anticancer effects of TLBZT against colorectal carcinoma in vitro. In present study, we evaluated the anticancer potential of TLBZT, used alone or in combination with low dose of 5-Fluorouracil (5-Fu), in CT26 colon carcinoma in vivo. CT26 colon carcinoma was established in BALB/c mice and treated with TLBZT, 5-Fu, or TLBZT plus 5-Fu. The tumor volumes were observed. Apoptosis was detected by TUNEL assay. Caspases activities were detected by colorimetric assay. Cell senescence was indentified by senescence β-galactosidase staining. Gene expression and angiogenesis was observed by immunohistochemistry or western blot. TLBZT significantly inhibited CT26 colon carcinoma growth. TLBZT elicited apoptosis in CT26 colon carcinoma, accompanied by Caspase-3, 8, and 9 activation and PARP cleavage, and downregulation of XIAP and Survivin. TLBZT also induced cell senescence in CT26 colon carcinoma, with concomitant upregulation of p16 and p21 and downregulation of RB phosphorylation. In addition, angiogenesis and VEGF expression in CT26 colon carcinoma was significantly inhibited by TLBZT treatment. Furthermore, TLBZT significantly enhanced anticancer effects of 5-Fu in CT26 colon carcinoma. TLBZT exhibited significantly anticancer effect, and enhanced the effects of 5-Fu in CT26 colon carcinoma, which may correlate with induction of apoptosis and cell senescence, and angiogenesis inhibition. The present study provides new insight into TCM approaches for colon cancer treatment that are worth of further study.

  6. [Mining analysis and experience summary for chronic atrophic gastritis cases treated by Professor LIU Feng-bin].

    Science.gov (United States)

    Hou, Zheng-kun; Liu, Feng-bin; Li, Pei-wu; Zhuang, Kun-hai

    2015-06-01

    To summarize Professor LIU Feng-bin's clinical experience and theoretical thoughts on chronic atrophic gastritis (CAG), the study group designed a retrospective study on his case series and expert interview. First of all, the data of CAG patients treated in the First Affiliated Hospital of Guangzhou University of Chinese Medicine between 2009 and 2013, e. g. herbs, diseases, syndrome type, prescription amount and number of herbs, was collected and processed. The statistical description and binary logistic regression were used to determined the syndrome type, initial basic remedy and modification. During the statistics, a complete and sub-group analysis was performed simultaneously. After the expert interview, the syndrome type and medication were finalized. As a result, a total of 228 CAG patients aged at (50.30 ± 10.18) were collected, including 151 males (66.23%). Of them, the TCM diagnosis and syndrome type were extracted from the information of 157 patients, including 115 cases with gastric stuffiness, 23 cases with gastric pain, 19 missing cases, 2 cases with spleen-stomach weakness syndrome, 57 cases with spleen deficiency and dampness-heat syndrome, 18 cases with spleen-stomach disharmony syndrome, 23 cases with syndrome of liver depression syndrome, 21 cases with liver qi invading stomach syndrome and 26 qi and yin deficiency syndrome, respectively. All of the 228 patients used totally 104 herbs, while the subgroups with 157 patients used 94 herbs. The most frequently used 15 herbs used in each groups were analyzed to determine the initial basic remedy and modification. Subsequently, based on the information of the sub-groups with 157 patients, with the syndrome type as the dependent variable, the logistic regression analysis was made on the most frequently used 32 herbs, in order to determined the modification in herbs for different syndrome types. After experts reviewed and modified, they believed the main causes of CAG were dietary irregularities

  7. Effect of RenNew-D as a sterilant on the performance of reused dialyzers.

    Science.gov (United States)

    Gagnon, R F; Adkar, V; Kaye, M

    1986-12-01

    RenNew-D (Alcide), a novel demand-release sporocidal agent, was employed instead of formaldehyde in the reprocessing for reuse of cuprophan hollow fiber dialyzers (Gambro) and the performance of these dialyzers was evaluated over 40 consecutive dialyses in six patients on maintenance hemodialysis. When RenNew-D was part of automated reprocessing performed with 4.3% bleach as specified by the manufacturer (Lixivitron), dialyzer survival was prolonged (16.7 +/- 7.2 uses) and hemodialysis neutropenia was unchanged with reuse. When RenNew-D was part of manual reprocessing conducted in the absence of bleach, marked improvement in dialyzer biocompatibility was observed but with a decreased survival (4.8 +/- 3.0). The majority of dialyzer failures were due to a fall in fiber bundle volume below a 85% set limit. Small solute clearances were maintained with both types of reprocessing. Dialyses were well tolerated throughout. Our data suggest that RenNew-D is a safe and efficacious product which can serve as a valuable alternative to formaldehyde for the purpose of dialyzer reuse.

  8. Die Geburt des Kosmos aus dem Nichts die Theorie des inflationären Universums

    CERN Document Server

    Guth, Alan

    2002-01-01

    Selten wird die Wissenschaft über Nacht so stark revolutioniert wie die Kosmologie durch Alan Guths Entdeckung der inflationären Theorie des Universums. Noch seltener gelingt es dem Urheber einer solchen Revolution, eine derart verständliche und einprägsame Darstellung von einer der aufregendsten Epochen in der modernen Kosmologie zu geben. Sogar Kenner werden Neues lernen.

  9. The conversion in the René Girard’s mimetic theory

    Directory of Open Access Journals (Sweden)

    Agustín Moreno Fernández

    2014-12-01

    Full Text Available One of the specific peculiarities of René Girard’s mimetic theory is the recovery of the concept of conversion. In this article we expose, in a detailed way, the three senses of the conversion according to his thinking: novelistic, religious and epistemological. There is an interaction between the three senses and also different significations for each other.

  10. Schwerpunktseminar : "Dazugehören? Umgang mit Minderheiten" / Liliāna Vancāne

    Index Scriptorium Estoniae

    Vancāne, Liliāna

    2016-01-01

    17. -20. märtsini 2016 Tartus toimunud seminarist "Dazugehören? Umgang mit Minderheiten. Estland und Lettland gestern-heutu-morgen". Seminarist sotsiaalse kuuluvuse ja vähemuste teemal. Suurepäraselt korraldatud ürituse parim osa oli töötuba

  11. 赤凤逢源针刺手法治疗踝关节扭伤的研究%Study on the Chi Feng Feng Yuan manipulation of acupuncture in the treatment of ankle joint sprain

    Institute of Scientific and Technical Information of China (English)

    史莹莺

    2015-01-01

    目的:探讨赤凤逢源针刺手法治疗急性踝关节扭伤的临床疗效。方法:收治急性踝关节扭伤患者132例,按就诊顺序随机分为3组,针刺组44例,采用“赤凤逢源”法针刺治疗;教学组44例,参照《针灸学》治疗踝关节扭伤方法;扶他林组44例,采用扶他林乳剂外擦治疗。观察治疗后患者踝关节疼痛、肿胀及功能改善情况,并对3组患者治疗前、后踝关节症状评分进行比较。结果:3组患者治疗前后症状评分差值比较:①疼痛差值:针刺组2.59(0.92),教学组1.86(0.51),扶他林组1.5(0.876),F=21.669,P=0;肿胀差值:针刺组2.09(0.603),教学组2.09(0.96),扶他林组1.45(0.901),F=8.496,P=0;功能障碍:针刺组:2.14(1.091),教学组2.09(0.96),扶他林组1.77(0.642),F=2.053,P=0.133;总分差值:针刺组6.82(1.632),教学组6.18(1.968),扶他林组4.73(1.37),F=18.021,P=0。止痛效果针刺组疗效优于教学组更优于扶他林组(P1*2=0,P1*3=0,P2*3=0),肿胀疗效针刺组与教学组差不多但都优于扶他林组(P1*2=1.000,P1*3=0.001,P2*3=0.001),关节功能障碍疗效三组差别不大(P=0.133)。从总的疗效来看,针刺组与教学组疗效相近(P1*2=0.180),但均优于扶他林组(P1*2=0.18,P1*3=0.000,P2*3=0.000)。结论:赤凤逢源针刺手法治疗踝关节扭伤,能起到良好的活血止痛效果,值得临床推广应用。%Objective:To investigate the clinical curative effect of Chi Feng Feng Yuan acupuncture in the treatment of acute ankle sprain.Methods:132 patients with acute ankle joint sprain were selected.They were randomly divided into 3 groups according to the order of treatment.44 cases in the acupuncture group were given "Chi Feng Fegn Yuan" acupuncture therapy;the teaching group with 44 cases refered to the methods of "acupuncture" in the treatment of ankle joint sprain;the voltaren group with 44 cases were given votalin

  12. Spatial distribution and risk assessment of heavy metals in soil near a Pb/Zn smelter in Feng County, China.

    Science.gov (United States)

    Shen, Feng; Liao, Renmei; Ali, Amjad; Mahar, Amanullah; Guo, Di; Li, Ronghua; Xining, Sun; Awasthi, Mukesh Kumar; Wang, Quan; Zhang, Zengqiang

    2017-05-01

    A large scale survey and a small scale continuous monitoring was conducted to evaluate the impact of Pb/Zn smelting on soil heavy metals (HMs) accumulation and potential ecological risk in Feng County, Shaanxi province of China. Soil parameters including pH, texture, CEC, spatial and temporal distribution of HMs (Cd, Cu, Ni, Pb and Zn), and BCR fractionation were monitored accordingly. The results showed the topsoil in the proximity of smelter, especially the smelter area and county seat, were highly polluted by HMs in contrast to the river basins. Fractionation of Cd and Zn in soil samples revealed higher proportion of mobile fractions than other HMs. The soil Cd and Zn contents decreased vertically, but still exceeded the second level limits of Environmental Quality Standard for Soils of China (EQSS) within 80cm. The dominated soil pollutant (Cd) had higher ecological risk than Cu, Ni, Zn and Pb. The potential ecological risk (PER) factor of Cd were 65.7% and 100% in surrounding county and smelter area, respectively. The long-term smelter dust emission mainly contributed to the HMs pollution and posed serious environment risk to living beings. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Streptomyces pactum assisted phytoremediation in Zn/Pb smelter contaminated soil of Feng County and its impact on enzymatic activities

    Science.gov (United States)

    Ali, Amjad; Guo, Di; Mahar, Amanullah; Ma, Fang; Li, Ronghua; Shen, Feng; Wang, Ping; Zhang, Zengqiang

    2017-04-01

    Anthropogenic activities, such as industrial expansion, smelting, mining and agricultural practices, have intensified the discharge of potentially toxic trace elements (PTEs) into the environment, threatening human health and other organisms. To assist phytoremediation by sorghum in soil contaminated by smelters/mines in Feng County (FC), a pot experiment was performed to examine the phytoremediation potential of Streptomyces pactum (Act12) + biochar. The results showed that root uptake of Zn and Cd was reduced by 45 and 22%, respectively, while the uptake of Pb and Cu increased by 17 and 47%, respectively. The shoot and root dry weight and chlorophyll content improved after Act12 inoculation. β-glucosidase, alkaline phosphatase and urease activities in soil improved and antioxidant activities (POD, PAL, PPO) decreased after application of Act12 + biochar due to a reduction in stress from PTEs. BCF, TF and MEA confirmed the role of Act12 in the amelioration and translocation of PTEs. PCA analysis showed a correlation between different factors that affect the translocation of PTEs. Overall, Act12 promoted the phytoremediation of PTEs. Field experiments on Act12 + biochar may provide new insights into the rehabilitation and restoration of soils contaminated by mines.

  14. Inter-satellite calibration of FengYun 3 medium energy electron fluxes with POES electron measurements

    Science.gov (United States)

    Zhang, Yang; Ni, Binbin; Xiang, Zheng; Zhang, Xianguo; Zhang, Xiaoxin; Gu, Xudong; Fu, Song; Cao, Xing; Zou, Zhengyang

    2018-05-01

    We perform an L-shell dependent inter-satellite calibration of FengYun 3 medium energy electron measurements with POES measurements based on rough orbital conjunctions within 5 min × 0.1 L × 0.5 MLT. By comparing electron flux data between the U.S. Polar Orbiting Environmental Satellites (POES) and Chinese sun-synchronous satellites including FY-3B and FY-3C for a whole year of 2014, we attempt to remove less reliable data and evaluate systematic uncertainties associated with the FY-3B and FY-3C datasets, expecting to quantify the inter-satellite calibration factors for the 150-350 keV energy channel at L = 2-7. Compared to the POES data, the FY-3B and FY-3C data generally exhibit a similar trend of electron flux variations but more or less underestimate them within a factor of 5 for the medium electron energy 150-350 keV channel. Good consistency in the flux conjunctions after the inter-calibration procedures gives us certain confidence to generalize our method to calibrate electron flux measurements from various satellite instruments.

  15. Ultra high performance liquid chromatography coupled with electrospray ionization/quadrupole time-of-flight mass spectrometry for the rapid analysis of constituents in the traditional Chinese medicine formula Wu Ji Bai Feng Pill.

    Science.gov (United States)

    Duan, Shengnan; Qi, Wen; Zhang, Siwen; Huang, Kunkun; Yuan, Dan

    2017-10-01

    An ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry method in both positive and negative ion modes was established in order to comprehensively investigate the major constituents in Wu Ji Bai Feng Pill. Briefly, a Waters ACQUITY UPLC HSS C 18 column was used to separate the aqueous extract of Wu Ji Bai Feng Pill. A total of 0.1% formic acid in acetonitrile and 0.1% aqueous formic acid v/v were used as the mobile phase. All analytes were determined using quadrupole time-of-flight mass spectrometry with electrospray ionization source in positive and negative ion modes. At length, a total of 173 components including flavones and their glycosides, monoterpene glycosides, triterpene saponins, phenethylalchohol glycosides, iridoid glycosides, phthalides, tanshinones, phenolic acids, sesquiterpenoids and cyclopeptides were identified or tentatively characterized in Wu Ji Bai Feng Pill in an analysis of 16.0 min based on the accurate mass and tandem mass spectrometry behaviors. The developed method is rapid and highly sensitive to characterize the chemical constituents of Wu Ji Bai Feng Pill, which could not only be used for chemical standardization and quality control of Wu Ji Bai Feng Pill, but also be helpful for further study in vivo metabolism of Wu Ji Bai Feng Pill. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. El cuerpo violentado en La carne de René, de Virgilio Piñera

    Directory of Open Access Journals (Sweden)

    Rogelio Castro Rocha

    2014-04-01

      The body is one of the most common motifs in the narration of the Cuban writer Virgilio Piñera (1912-1979. This paper analyses its configuration in the novel La carne de René (1952. As a starting, point two approaches to the protagonist’s body are distinguished. First, there are those who want to "corrupt" its physicality for pleasure – however René wants his body to remain intact – and second, there are those who want to modify its corporeality from physical aggression by using cruel methods that violate and wound the body, with the aim of worshipping the pain. To reinforce my analysis, I rely on some notions of the body that were carried out by Jean-Luc Nancy who sees the body as a limit of senses and Gilles Deleuze who elaborates on the "body without organs".

  17. Lyden Sker - et interview med Torben Ulrich og Søren Kjærgaard

    DEFF Research Database (Denmark)

    Kristensen, Thomas Bjørnsten

    2009-01-01

    Da musikeren, poeten og tennisspilleren Torben Ulrich i Seattle mødte jazzpianisten og komponisten Søren Kjærgaard udviklede det sig til en dybdegående udforskning af feltet mellem lyd og ord, stilhed og puls, rum og nærvær. Deres fælles bestræbelser kulminerede i foråret 2009 med det eksperiment......Da musikeren, poeten og tennisspilleren Torben Ulrich i Seattle mødte jazzpianisten og komponisten Søren Kjærgaard udviklede det sig til en dybdegående udforskning af feltet mellem lyd og ord, stilhed og puls, rum og nærvær. Deres fælles bestræbelser kulminerede i foråret 2009 med det...

  18. MCNP-REN a Monte Carlo tool for neutron detector design

    CERN Document Server

    Abhold, M E

    2002-01-01

    The development of neutron detectors makes extensive use of the predictions of detector response through the use of Monte Carlo techniques in conjunction with the point reactor model. Unfortunately, the point reactor model fails to accurately predict detector response in common applications. For this reason, the general Monte Carlo code developed at Los Alamos National Laboratory, Monte Carlo N-Particle (MCNP), was modified to simulate the pulse streams that would be generated by a neutron detector and normally analyzed by a shift register. This modified code, MCNP-Random Exponentially Distributed Neutron Source (MCNP-REN), along with the Time Analysis Program, predicts neutron detector response without using the point reactor model, making it unnecessary for the user to decide whether or not the assumptions of the point model are met for their application. MCNP-REN is capable of simulating standard neutron coincidence counting as well as neutron multiplicity counting. Measurements of mixed oxide fresh fuel w...

  19. Castration Has Antihypertensive and Organoprotective Effects in Male but Not in Female Heterozygous Ren-2 Rats

    Czech Academy of Sciences Publication Activity Database

    Vaněčková, Ivana; Husková, Z.; Vaňourková, Z.; Červenka, L.

    2011-01-01

    Roč. 34, č. 1 (2011), s. 46-52 ISSN 1420-4096 R&D Projects: GA MŠk(CZ) 1M0510 Institutional research plan: CEZ:AV0Z50110509 Keywords : Ren-2 rats * hypertension * sexual dimorphism * age * sex hormones * renin-angiotensin system Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 1.464, year: 2011

  20. A renúncia de Fidel Castro: continuidade na sucessão presidencial

    Directory of Open Access Journals (Sweden)

    Isabele Villwock Bachtold

    2010-10-01

    Full Text Available Cuba atualmente vive uma nova fase, pautada na possível reforma do sistema socialista em vigor no país desde a Revolução Cubana de 1959. Este artigo busca analisar as implicações que a recente renúncia de Fidel Castro à presidência cubana acarretará para a ilha e para o cenário internacional como um todo.

  1. MCNP-REN: a Monte Carlo tool for neutron detector design

    International Nuclear Information System (INIS)

    Abhold, M.E.; Baker, M.C.

    2002-01-01

    The development of neutron detectors makes extensive use of the predictions of detector response through the use of Monte Carlo techniques in conjunction with the point reactor model. Unfortunately, the point reactor model fails to accurately predict detector response in common applications. For this reason, the general Monte Carlo code developed at Los Alamos National Laboratory, Monte Carlo N-Particle (MCNP), was modified to simulate the pulse streams that would be generated by a neutron detector and normally analyzed by a shift register. This modified code, MCNP-Random Exponentially Distributed Neutron Source (MCNP-REN), along with the Time Analysis Program, predicts neutron detector response without using the point reactor model, making it unnecessary for the user to decide whether or not the assumptions of the point model are met for their application. MCNP-REN is capable of simulating standard neutron coincidence counting as well as neutron multiplicity counting. Measurements of mixed oxide fresh fuel were taken with the Underwater Coincidence Counter, and measurements of highly enriched uranium reactor fuel were taken with the active neutron interrogation Research Reactor Fuel Counter and compared to calculation. Simulations completed for other detector design applications are described. The method used in MCNP-REN is demonstrated to be fundamentally sound and shown to eliminate the need to use the point model for detector performance predictions

  2. Multi-satellites normalization of the FengYun-2s visible detectors by the MVP method

    Science.gov (United States)

    Li, Yuan; Rong, Zhi-guo; Zhang, Li-jun; Sun, Ling; Xu, Na

    2013-08-01

    After January 13, 2012, FY-2F had successfully launched, the total number of the in orbit operating FengYun-2 geostationary meteorological satellites reached three. For accurate and efficient application of multi-satellite observation data, the study of the multi-satellites normalization of the visible detector was urgent. The method required to be non-rely on the in orbit calibration. So as to validate the calibration results before and after the launch; calculate day updating surface bidirectional reflectance distribution function (BRDF); at the same time track the long-term decay phenomenon of the detector's linearity and responsivity. By research of the typical BRDF model, the normalization method was designed. Which could effectively solute the interference of surface directional reflectance characteristics, non-rely on visible detector in orbit calibration. That was the Median Vertical Plane (MVP) method. The MVP method was based on the symmetry of principal plane, which were the directional reflective properties of the general surface targets. Two geostationary satellites were taken as the endpoint of a segment, targets on the intersecting line of the segment's MVP and the earth surface could be used as a normalization reference target (NRT). Observation on the NRT by two satellites at the moment the sun passing through the MVP brought the same observation zenith, solar zenith, and opposite relative direction angle. At that time, the linear regression coefficients of the satellite output data were the required normalization coefficients. The normalization coefficients between FY-2D, FY-2E and FY-2F were calculated, and the self-test method of the normalized results was designed and realized. The results showed the differences of the responsivity between satellites could up to 10.1%(FY-2E to FY-2F); the differences of the output reflectance calculated by the broadcast calibration look-up table could up to 21.1%(FY-2D to FY-2F); the differences of the output

  3. Effects of Lactobacillus salivarius Ren on cancer prevention and intestinal microbiota in 1, 2-dimethylhydrazine-induced rat model.

    Science.gov (United States)

    Zhang, Ming; Fan, Xing; Fang, Bing; Zhu, Chengzhen; Zhu, Jun; Ren, Fazheng

    2015-06-01

    Probiotics have been suggested as a prophylactic measure in colon cancer. The aim of this study was to investigate the impact of Lactobacillus salivarius Ren (Ren) in modulating colonic microbiota structure and colon cancer incidence in a rat model after injection with 1,2-dimethyl hydrazine (DMH). The results indicated that oral administration of Ren could effectively suppress DMH-induced colonic carcinogenesis. A significant decrease in cancer incidence (87.5% to 25%) was detected in rats fed with a dose of 5 × 10(10) CFU/kg bodyweight per day. Using denaturing gradient gel electrophoresis and Real-time PCR combined with multivariate statistical methods, we demonstrated that injection with DMH significantly altered the rat gut microbiota, while Ren counteracted these DMH-induced adverse effects and promoted reversion of the gut microbiota close to the healthy state. Tvalue biplots followed by band sequencing identified 21 bacterial strains as critical variables affected by DMH and Ren. Injection of DMH significantly increased the amount of Ruminococcus species (sp.) and Clostridiales bacteria, as well as decreasing the Prevotella sp. Administration of Ren reduced the amount of Ruminococcus sp., Clostridiales bacteria, and Bacteroides dorei, and increased the amount of Prevotella. Real-time PCR results were consistent with the results derived by t-value biplots. These findings suggested that Ren is a potential agent for colon cancer prevention. In conclusion, the results in the present study suggest a potential therapeutic approach based on the modulation of intestinal microflora by probiotics may be beneficial in the prevention of colorectal carcinogenesis.

  4. 1964: um golpe de classe? (Sobre um livro de René Dreifuss 1964: a class putsch? (About a book by René Dreifuss

    Directory of Open Access Journals (Sweden)

    Maria Victória de Mesquita Benevides

    2003-01-01

    Full Text Available Republica-se aqui o comentário feito na época da sua publicação do importante livro do recentemente falecido cientista político René Armand Dreifuss sobre o papel de uma "elite orgânica" de orientação empresarial na desestabilização do regime democrático pré-1964, no sentido da criação de uma "ordem empresarial" após o "golpe de classe" de 1964 (1964: a conquista do Estado - ação política, poder e golpe de classe. Para a autora a noção de "golpe de classe" é insuficiente para dar conta da dinâmica política e econômica da época, assim como se revelaram frustrados os esforços para constituir uma "ordem empresarial", em vista do impulso estatizante promovido pelo regime militar. Destaca-se, contudo, o valor do livro, que é aqui relembrado, junto com o nome do seu autor.The commentary made at the time of its publication about the important book by the recently deceased political scientist René Armand Dreifuss on the role of an "organic elite" in the overthrowing of the pre-1964 Brazilian regime aiming at an "entrepreneurial order" after the "class putsch" of 1964 is here republished. It is argued that the idea of "class putsch" is too narrow to cover the political and economic dynamics of the epoch, and that the efforts to constitute an "entrepreneurial order" were frustrated by the impulse toward a growth of State functions promoted by the military regime. However, the review emphasizes the merits of the book, which is here brought to memory along with the name of its author.

  5. René Metras, un hombre de nuestro tiempo. Galeria René Metras y la vanguardia estética en Barcelona

    Directory of Open Access Journals (Sweden)

    Mª del Carmen Briones Brú

    2013-07-01

    Full Text Available El propósito de este trabajo es reconocer y poner de relieve la figura, no siempre reconocida en los medios artísticos actuales de un hombre, René Metras. Vinculado desde los años cuarenta a movimientos artísticos catalanes de posguerra, participó con los intelectuales y jóvenes artistas catalanes, con su esfuerzo, ímpetu y dedicación personal, siendo una figura muy significativa en los primeros momentos de las vanguardias del arte español de los años 50 y 60. En octubre de 1962 abre las puertas de la galería que lleva su nombre, en la calle Consejo de Ciento, 331 de Barcelona alentado por la idea de mostrar al público barcelonés un arte distinto e innovador al que se mostraba en la mayoría de las galerías de arte. Pionero en mostrar lo que pasaba fuera de nuestro país, desde su inauguración apostó por las vanguardias europeas y, en sus salas, pudo verse por primera vez a los grandes artistas del siglo XX; promovió, fiel a su ideario, a jóvenes y relevantes artistas catalanes y del resto de la Península, defendiendo con pureza y rigor el arte abstracto e informalista. René Metras no sólo abrió sus puertas a Barcelona, también abrió Barcelona al mundo artístico internacional, siendo su galería un referente mundial de la vanguardia estética de Barcelona.

  6. Lactobacillus salivarius REN counteracted unfavorable 4-nitroquinoline-1-oxide-induced changes in colonic microflora of rats.

    Science.gov (United States)

    Zhang, Ming; Qiao, Xuewei; Zhao, Liang; Jiang, Lu; Ren, Fazheng

    2011-12-01

    Probiotics and carcinogens both have a significant effect on the microfloral composition of the human intestine. The objective of this study was to investigate the impact of an important carcinogen, 4-Nitroquinoline-1-Oxide on colonic microflora and the efficacy of the probiotic Lactobacillus salivarius REN as an agent of counteracting these effects. Using denaturing gradient gel electrophoresis (DGGE) combined with redundancy analysis, we demonstrated that both 4-Nitroquinoline-1-Oxide and L. salivarius REN significantly altered the bacterial communities of rat colons. A total of 27 bacterial strains were identified as being affected by treatment with 4-Nitroquinoline-1-Oxide or L. salivarius REN using a t-value biplot combined with band sequencing. 4-Nitroquinoline-1-Oxide treatment increased the abundance of two potential pathogens (one Helicobacter strain and one Desulfovibrio strain), as well as reducing the abundance of two potentially beneficial strains (one Ruminococcaceae strain and one Rumen bacteria). The Helicobacter strain was initally detected in carcinogen-treated rat intestinal microflora, but L. salivarius REN treatment effectively suppressed the growth of the Helicobacter strain. These results suggested that L. salivarius REN may be a potential probiotic, efficiently acting against the initial infection with, and the growth of pathogenic bacteria.

  7. Der Einfluss des mikrovaskulären Systems auf das Überleben eines Hauttransplantats

    OpenAIRE

    Motsch, Benjamin

    2017-01-01

    Transplantierte Organe benötigen eine zuverlässige Versorgung über das Gefäßsystem. Daher richtet diese Studie ihr Augenmerk darauf, ob eine Hemmung von Thrombozyten, sowohl allein als auch in Kombination mit einem mTOR-Hemmer, einen positiven Effekt auf die Ausprägung der mikrovaskulären Struktur in Hauttransplantaten bei einem allogenen Mausmodell hat. Für die Hauttransplantation wurde die Haut von C57BL6 (H-2b) als Spendertiere auf CBA/J(H-2k) Mäuse übertragen. Auf diese Weise wurde eine v...

  8. Faith and grace in the thought of Tanabe Hajime and of Søren Kierkegaard

    OpenAIRE

    Henneberg, Peter

    2010-01-01

    The subject matter of this essay is to compare the conceptions which Søren Kierkegaard and Tanabe Hajime have of the notions of religious faith and of divine grace. The investigation was triggered by the observation that Tanabe’s philosophy owes much to the thought of Kierkegaard, and by the fact that Kierkegaard has been trained as a Danish Protestant theologian while Tanabe adopted for himself positions of Japanese Pure Land Buddhism. After a rigorous analysis of the notions of faith and...

  9. Diana og Kirke. Den klassiske mytes metamorfose i italienske Renæssance

    DEFF Research Database (Denmark)

    Cecchini, Leonardo

    Den klassiske myte har en særlig stilling i det, Aleida Assmann har kaldt kulturelle Gedächtnis. Takket være dens store udbredelse i den vestlige kultur (både i litteratur, kunst og i andre områder), har den en tendens til at virke, snarere end som konkret ”tekst”, som et udbredt kulturel registe...... renæssancekulturen omarbejder den klassiske myte. Som case-stories vil jeg anvende Kirke-myten og ”den mytiske jagt” (Diana og Aktæon) og vise, hvordan de bliver genanvendt, tilpasset og fortolket i tekster af Petrarca, Boccaccio, Machiavelli og Gelli....

  10. The brain of René Descartes (1650): A neuro-anatomical analysis.

    Science.gov (United States)

    Philippe, Charlier; Isabelle, Huynh-Charlier; Philippe, Froesch; Russell, Shorto; Nadia, Benmoussa; Alain, Froment; Dominique, Grimaud-Hervé; Saudamini, Deo; Anaïs, Augias; Lou, Albessard; Antoine, Balzeau

    2017-07-15

    The skull of René Descartes is held in the National Museum of Natural History since the 19th c. Up to date, only anthropological examinations were carried out, focusing on the cranial capacity and phrenological interpretation of the skull morphology. Using CT-scan based 3D technology, a reconstruction of the endocast was performed, allowing for its first complete description and inter-disciplinary analysis: assessment of metrical and non-metrical features, retrospective diagnosis of anatomical anomalies, and confrontation with neuro-psychological abilities of this well-identified individual. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Zum Erleben von Thrills und anderen starken emotionalen Reaktionen beim Musikhören

    OpenAIRE

    Schönberger, Jörg

    2003-01-01

    Obwohl unbestritten ist, dass Musik in der Lage ist, starke emotionale Reaktionen auszulösen, hat sich die Musikpsychologie wenig mit den Emotionen beschäftigt, die Menschen beim Musikhören erleben. Zwei mögliche Zugänge zum Erfassen solch starker emotionaler Reaktionen sind die Ansätze von John A. Sloboda und Alf Gabrielsson. Sloboda nutzt für seinen Ansatz das Phänomen der "Thrills" — physiologische Begleiterscheinungen starker emotionaler Reaktionen wie z.B. Gänsehaut, Schauer, die ü...

  12. Lactobacillus salivarius Ren prevent the early colorectal carcinogenesis in 1, 2-dimethylhydrazine-induced rat model.

    Science.gov (United States)

    Zhu, J; Zhu, C; Ge, S; Zhang, M; Jiang, L; Cui, J; Ren, F

    2014-07-01

    The objective of this study was to investigate the impact of Lactobacillus salivarius Ren (LS) on modulating colonic micro flora structure and influencing host colonic health in a rat model with colorectal precancerous lesions. Male F344 rats were injected with 1, 2-dimethylhydrazine (DMH) and treated with LS of two doses (5 × 10(8) and 1 × 10(10) CFU kg(-1) body weight) for 15 weeks. The colonic microflora profiles, luminal metabolites, epithelial proliferation and precancerous lesions [aberrant crypt foci (ACF)] were determined. A distinct segregation of colonic microflora structures was observed in LS-treated group. The abundance of one Prevotella-related strain was increased, and the abundance of one Bacillus-related strain was decreased by LS treatment. These changes were accompanied by increased short-chain fatty acid levels and decreased azoreductase activity. LS treatment also reduced the number of ACF by c. 40% and suppressed epithelial proliferation. Lactobacillus salivarius Ren improved the colonic microflora structures and the luminal metabolisms in addition preventing the early colorectal carcinogenesis in DMH-induced rat model. Colonic microflora is an important factor in colorectal carcinogenesis. Modulating the structural shifts of microflora may provide a novel option for preventing colorectal carcinogenesis. This study suggested a potential probiotic-based approach to modulate the intestinal microflora in the prevention of colorectal carcinogenesis. © 2014 The Society for Applied Microbiology.

  13. Review of Formen des Klärens by Christian Erbacher

    Directory of Open Access Journals (Sweden)

    Tea Jankovic

    2016-06-01

    Full Text Available Book review of Christian Erbacher's Formen des Klärens, Literarisch-Philosophische Darstellungsmittel in Wittgensteins Schriften, Münster: mentis 2015. *** Christian Erbacher’s Formen des Klärens, Literarisch-Philosophische Darstellungsmittel in Wittgensteins Schriften, which I would translate as Forms of Elucidating, Literary-Philosophical Means of Presentation in Wittgenstein’s Works, comprises and critically analyzes the most important phases of almost a hundred years of both English and German speaking Wittgenstein scholarship on the form of his literary-philosophical presentation. Furthermore, Erbacher demonstrates a thorough first hand knowledge of Wittgenstein’s manuscripts and manner of work, while at the same time offering an interpretation of the Tractatus logico-philosophicus, as well as later works, that is capable of comprehending both Wittgenstein’s serious and intense ethical and aesthetic preoccupations, as well as his significant contributions to logic and philosophy of language. Furthermore, despite its density, Erbacher’s slender book admirably achieves an elegant lucidity. Thus it performatively shows the unity of aesthetic-rhetorical form and philosophical content, as well as the ethical ideal of clarity at the core of Wittgenstein’s concerns.

  14. La crítica de René Girard al humanismo

    Directory of Open Access Journals (Sweden)

    Moreno Fernández, Agustín

    2016-06-01

    Full Text Available In René Girard’s work there are a lot of critics to the humanism and the humanists. First of all, in this article we will deal with a definition of this concept and his historiographic problem. There is a big contrast between the topics and ideals of the humanism and the mimetic theory. We study the explicit Girard’s critics to the humanists and finally we present one perspective that allows to consider himself like a humanist thinker.La obra de René Girard está salpicada de críticas al humanismo y a los humanistas. En este estudio nos preguntamos en primer lugar qué es el humanismo, haciéndonos cargo de la problemática historiográfica. Presentamos el contraste existente entre los tópicos e ideales humanistas y las ideas que se derivan de la teoría mimética. Estudiamos las críticas explícitas de Girard a los humanistas y, por último, adoptamos una perspectiva que permite calificarlo a él mismo como un humanista.

  15. Calculation and evaluation of the activation cross sections for 187Re(n,2n)186m,gRe reactions

    International Nuclear Information System (INIS)

    Huang Xiaolong; Lu Hanlin; Zhou Chunmei

    1998-01-01

    The activation cross sections for 187 Re(n,2n) 186m,g Re reactions are calculated using UNF code. The calculations are in good agreement with the re-evaluated measured data. Finally the excitation function for 187 Re(n,2n) 186m,g Re reactions are evaluated and recommended based on present calculations and evaluated decay data

  16. Comment on "Timing and nature of the Xinlin-Xiguitu Ocean: constraints from ophiolitic gabbros in the northern Great Xing'an Range, eastern Central Asian Orogenic Belt" by Feng et al. (2016)

    Science.gov (United States)

    Ni, Dong-Hong

    2017-09-01

    We disagree the transitional supra-subduction zone model of Feng et al. (Int J Earth Sci (Geol Rundsch) 105:491-505, 2016) for the tectonic setting of Jifeng ophiolite suite in NE China. Existence of the komatiite in the Jifeng ophiolite indicates an oceanic plateau environment for this ophiolite suite within the so-called Xinlin-Xiguitu ocean.

  17. Functional role of oppA encoding an oligopeptide-binding protein from Lactobacillus salivarius Ren in bile tolerance.

    Science.gov (United States)

    Wang, Guohong; Li, Dan; Ma, Xiayin; An, Haoran; Zhai, Zhengyuan; Ren, Fazheng; Hao, Yanling

    2015-08-01

    Lactobacillus salivarius is a member of the indigenous microbiota of the human gastrointestinal tract (GIT), and some L. salivarius strains are considered as probiotics. Bile tolerance is a crucial property for probiotic bacteria to survive the transit through the GIT and exert their beneficial effects. In this work, the functional role of oppA encoding an oligopeptide transporter substrate-binding protein from L. salivarius Ren in bile salt tolerance was investigated. In silico analysis revealed that the oppA gene encodes a 61.7-kDa cell surface-anchored hydrophilic protein with a canonical lipoprotein signal peptide. Homologous overexpression of OppA was shown to confer 20-fold higher tolerance to 0.5 % oxgall in L. salivarius Ren. Furthermore, the recombinant strain exhibited 1.8-fold and 3.6-fold higher survival when exposed to the sublethal concentration of sodium taurocholate and sodium taurodeoxycholate, respectively, while no significant change was observed when exposed to sodium glycocholate and sodium glycodeoxycholate (GDCA). Our results indicate that OppA confers specific resistance to taurine-conjugated bile salts in L. salivarius Ren. In addition, the OppA overexpression strain also showed significant increased resistance to heat and salt stresses, suggesting the protective role of OppA against multiple stresses in L. salivarius Ren.

  18. Moderate additive effects of endothelin receptor A blockade in Ren-2 transgenic rats subjected to various types of RAS blockade

    Czech Academy of Sciences Publication Activity Database

    Vaněčková, Ivana; Řezáčová, Lenka; Kuneš, Jaroslav; Zicha, Josef

    2016-01-01

    Roč. 159, Aug 15 (2016), s. 127-154 ISSN 0024-3205 R&D Projects: GA MZd(CZ) NV15-25396A Institutional support: RVO:67985823 Keywords : aliskiren * captopril * atrasentan * hypertension * losartan * ren-2 transgenic rats Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 2.936, year: 2016

  19. YU Ren-cun(郁仁存)——A Famous Oncologist in Integrative Medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ YU Ren-cun was born on August 1,1934.After graduating from Jiangxi Medical College in 1955,he took part in the very first Western Doctors' Class for Learning Traditional Chinese Medicine (TCM) held in Beijing from March 1959 to December 1961.Prof.YU systematically learned TCM while taking this class.Since 1962,he has been working in the Beijing Hospital of Traditional Chinese Medicine,eventually being promoted to a Chief Physician by the Beijing Municipal Government in May of 1981.In 1997,Prof.YU was selected as a well-known veteran for the National TCM Doctor Inheritance Work by the State Administration of Traditional Chinese Medicine (SATCM).The State Council of China has awarded him a special subsidy every month for his excellent work.

  20. Complete genome sequence of Lactobacillus salivarius Ren, a probiotic strain with anti-tumor activity.

    Science.gov (United States)

    Sun, Erna; Ren, Fazheng; Liu, Songling; Ge, Shaoyang; Zhang, Ming; Guo, Huiyuan; Jiang, Lu; Zhang, Hao; Zhao, Liang

    2015-09-20

    Lactobacillus salivarius Ren (LsR) (CGMCC No. 3606) is a probiotic strain that was isolated from the feces of a healthy centenarian living in Bama, Guangxi, China. Previous studies have shown that this strain decreases 4-nitroquinoline 1-oxide (4-NQO)-induced genotoxicity in vitro. It also suppresses 4-NQO-induced oral carcinogenesis and 1,2-dimethylhydrazine (DMH)-induced colorectal carcinogenesis, and therefore may be used as an adjuvant therapeutic agent for cancer. Here, we report the complete genome sequence of LsR that consists of a circular chromosome of 1751,565 bp and two plasmids (pR1, 176,951 bp; pR2, 49,848 bp). Copyright © 2015 Elsevier B.V. All rights reserved.

  1. René Girard and the Mimetic Nature of Eating Disorders.

    Science.gov (United States)

    Strand, Mattias

    2018-03-07

    French historian and literary critic René Girard (1923-2015), most widely known for the concepts of mimetic desire and scapegoating, also engaged in the discussion of the surge of eating disorders in his 1996 essay Eating Disorders and Mimetic Desire. This article explores Girard's ideas on the mimetic nature and origin of eating disorders from a clinical psychiatric perspective and contextualizes them within the field of eating disorders research as well as in relation to broader psychological, sociological and anthropological models of social comparison and non-consumption. Three main themes in Girard's thinking on the topic of eating disorders are identified and explored: the 'end of prohibitions' as a driving force in the emergence of eating disorders, eating disorders as a phenomenon specific to modernity, and the significance of 'conspicuous non-consumption' in the emergence of eating disorders.

  2. Dem Sog der Arbeit widerstehen. Leben im egalitären Modell

    Directory of Open Access Journals (Sweden)

    Aschermann Ellen

    2007-07-01

    Full Text Available Die Autorinnen untersuchen die Einschätzungen von deutschschweizer Ehepaaren und ihren heranwachsenden Kindern zum Leben in einem egalitären Familienmodell. Die Längsschnittstudie umfasst dabei einen Zeitraum von 10 Jahren. In halbstrukturierten Interviews werden die Veränderungen in der Organisation in Arbeits-, Haushalts- und Familienbereich erhoben und mittels qualitativer Analyse strukturiert. Der erste Band enthält die theoretischen Grundlagen und die Befunde zu den Veränderungen bei den Eltern. Im zweiten Band wird auf die Erfahrungen der Kinder eingegangen, die in diesen Familien aufwuchsen. Auch sie wurden mit halbstrukturierten Interviews befragt. Zusätzlich wird die Kinderperspektive mit einer stärker traditionell aufwachsenden Kontrollgruppe verglichen.

  3. Die linke und die rechte todesauffassung: Zur kritik einer antitotalitären thanatologie

    Directory of Open Access Journals (Sweden)

    Kuljić Todor

    2011-01-01

    Full Text Available Hier sind die tiefere Schichten in der Todesauffassung bei der Ideologien der Linke und der Rechte untersucht und die Frage nach ihren antitotalitären Glei­chsetzung in punkto Betrachtung gestellt. Zu diesem Zweck werden verschiedene Opfersauffassungen und verschiedene Heilshoffnungen, aber auch verschiedene Ideolosierungen des Todes im Faschismus und Sozialismus gelegt, verglichen und in einen breiteren Kontext gestellt. Daraus folgt der starke Kluft zwischen linken und rechten Auffassung von normalen Lebensumständen. Die Herrschaft (nicht der Gott formiert und auf ideologische Weise nützt Angst vom Tod. Für die kritische Theorie ist die Gegenüberstellung von Leben und Tod ein Teil von emanzipatorische Praxis und Kapitalismuskritik. Die dargelegte Kritik der neoliberalen Thanathologie ist ein Teil von dieser Absicht.

  4. La reducción de lo posible. René Thom y el determinismo causal

    Directory of Open Access Journals (Sweden)

    Miguel Espinoza

    2009-12-01

    Full Text Available La tesis principal de este ensayo estipula que el determinismo causal es una propiedad de la naturaleza y el primer principio de la inteligibilidad natural. El desarrollo de esta tesis utiliza como hilo conductor el pensamiento de René Thom. Esto significa que el determinismo causal se examina en su relación con la estabilidad y la inestabilidad, el desafío de la mecánica cuántica, las raíces aporéticas de la ciencia tal como la dualidad determinismo-indeterminismo, y finalmente, en su relación con el método para ponerlo de manifiesto, es decir la reducción de lo posible.

  5. Size-affected single-slip behavior of René N5 microcrystals

    International Nuclear Information System (INIS)

    Shade, P.A.; Uchic, M.D.; Dimiduk, D.M.; Viswanathan, G.B.; Wheeler, R.; Fraser, H.L.

    2012-01-01

    Highlights: ► Microcompression testing was conducted on the single crystal superalloy René N5. ► All microcrystals exhibited size-affected plastic flow. ► Dendrite core microcrystals were stronger than those from interdendritic regions. - Abstract: Microcompression testing was conducted on the cast single crystal nickel-base superalloy René N5. Microcrystals were selectively fabricated from either dendrite core or interdendritic regions. The compression axis was oriented for single-slip deformation and microcrystal diameters ranged from 2.5 to 80 μm. All microcrystals displayed several hallmarks of size-affected plastic flow, including a size-affected and stochastic flow-stress and initial strain hardening rate, as well as an intermittent flow response. The magnitude of size-affected flow-stress scaling behavior was dependent upon the plastic strain level of the flow-stress measurement, with increasing size-dependence for increasing strain levels. TEM analysis demonstrated the activation of multiple slip-systems, despite the microcrystals being oriented for single-slip deformation. Zig-zag slip was also observed in microcrystals that achieved flow stresses of ∼1300 MPa or higher. For microcrystals fabricated within interdendritic regions the flow-stress values are, on average, lower compared to dendrite core microcrystals. This difference in flow-stress is especially pronounced for microcrystals which are 5 μm in diameter. The microcrystal diameter for which bulk-like properties are estimated to be observed is approximately 350 μm, which is approaching the measured primary dendrite arm spacing for this crystal (430 μm).

  6. [Clinical experience and academic thoughts of Professor LIU Feng-bin on case series of gastroesophageal reflux disease based on data mining].

    Science.gov (United States)

    Hou, Zheng-Kun; Li, Ji-Ping; Chen, Zhuo-Qun; Liu, Feng-Bin

    2018-03-01

    To analyze and summarize Professor LIU Feng-bin's clinical experience and academic thoughts on gastroesophageal reflux disease (GERD), the study group adopted the retrospective study for case series and expert interview, extracted the retrospective data, including the herbs, diseases, syndrome type, medical expense and quantity of herbs of GERD patients attended the First Affiliated Hospital of Guangzhou University of Chinese Medicine. Statistical description and binary Logistic regression were used for the identification and modification of syndrome type and initial core herbs. After expert interviews were performed for the syndrome type and herbs, the final scheme were formed. A total of 112 GERD patients ages(48.97±13.13)y; male: 35 (31.3%), female: 77(68.7%) were enrolled. The numbers of patients with liver and stomach incoordination syndrome, heat stagnation of liver and stomach syndrome, syndrome of dual deficiency of Qi and Yin, syndrome of spleen deficiency and dampness-heat, spleen-stomach disharmony syndrome were 40, 26, 19, 17 and 10, respectively. The patients used totally 80 herbs, and 26 of them had significant differences among different syndrome groups. According to the logistic regression analysis on the 23 herbs used by 112 patients, the herbs scheme was modified for the second time. After the expert interviews and modification, the final consensus was reached. The main causes for GERD were dietary irregularities, moodiness, and weak constitution. The basic mechanism of GERD was spleen deficiency with Qi adverseness. The spleen-stomach disharmony syndrome was deleted by expert interviews. The 10 core herbs for GERD treatment were Taizishen(Pseudostellariae Radix), Fuling(Poria), Baizhu(Atractylodismacrocephalae Rhizoma), Gancao(Glycyrrhizae Radix Et Rhizoma), Zhebeimu(Fritillariae Thunbergii Bulbus), Haipiaoxiao(Sepiae Endoconcha), Zhiqiao(Aurantii Fructus), Chenxiang(Alosewood), Pugongying(Taraxaci Herba), Zhizitan(Cape Jasmine Fruit). The

  7. A Reserva Ecológica Nacional (REN: sua importância para o ambiente e ordenamento do território

    Directory of Open Access Journals (Sweden)

    Ana Ramos Pereira

    2000-12-01

    Full Text Available THE NATIONAL ECOLOGICAL RESERVE (REN: ENVIRONMENT AND MANAGEMENT IMPLICATIONS. The National Ecological Reserve (REN defined in Decree-Law 93/90 of March 5th is the «basic and diversified biophysical structure that guarantees environmental protection, through the creation of restricted areas» at rish through erosion (littoral or slope, flooding and aquifer recharge. The REN valuation, whose main aspects are referred to here, was carried out by means of an analysis of Municipal Master Plans (PDM and a survey sent to all local authorities. As it was impossible to analyse the PDM of every district, a dis- trict differentiation was completed based on the biophysical index (Fig. 1 and 2, subsequently crossed by the district human pressure to obtain the district spatial differentiation of the environmental strain (Fig. 3. This allowed a standard district to be selected where the REN was analysed in full detail (Fig. 4 to 9. The survey allowed for the evaluation of the main conflicts in other districts between the REN and the goals of the PDM to be assessed, including the issues concerning the delimitation and the way the REN is seen by the councils and the citizens. The REN includes physical and biophysical systems (slope, fluvial, aquifer and littoral that tend never to coincide with the administrative divisions. It is urgent that a national network be created of REN areas, planned and managed through more integrated means and an inter-municipal collaboration that can only be effective if environmental education is promoted, on both formal and informal terms.

  8. Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

    OpenAIRE

    Chia-Hao Yeh; Christof K. Arnold; Yen-Hui Chen; Jung-Nein Lai

    2011-01-01

    Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT) in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI) and the World Health Organization quality of life (WHOQOL). Sixty-seven climacteric women with sleep difficulty intending to treat receive...

  9. “100 percent fun”: A case study of benefits from cold water surfing in Jæren, Norway

    OpenAIRE

    Elmahdy, Yasmine Mounir

    2015-01-01

    Master's thesis in International hotel and tourism management Norway is steadily progressing towards being a popular cold-water surf destination. The long Norwegian coastline is attracting an increasing number of surfers who surf year round in extreme weather conditions. The aim of this research is to identify the benefits acquired by Norwegian surfers surfing in cold water along the Jæren coast, south the city of Stavanger in Norway. This research adopted a phenomenological approach and q...

  10. Potenzielle Arzneimittelwechsel-wirkungen und unerwünschte Arzneimittelwirkungen bei stationären dermatologischen Patienten.

    Science.gov (United States)

    Koch, Lukas; Kränke, Birger; Aberer, Werner

    2016-11-01

    Informationen zur Häufigkeit von Arzneimittelwechselwirkungen und unerwünschten Arzneimittelwirkungen zu präsentieren und Hilfestellung zu leisten, wie diese wichtigen Probleme in der pharmakologischen Behandlung stationärer dermatologischer Patienten minimiert werden können. Die Medikation von 1 099 stationären dermatologischen Patienten wurde retrospektiv mittels einer Internet-basierten Software für Medikamenteninteraktionen (Diagnosia ® Check) auf Arzneimittelwechselwirkungen und unerwünschte Arzneimittelwirkungen analysiert. Wir beschreiben eine Gesamthäufigkeit relevanter Arzneimittelwechselwirkungen von 51,7 % mit durchschnittlich 3,2 Interaktionen pro betroffenem stationären Patienten. Arzneimittelkombinationen, die gemieden werden sollten, wurden bei 5,7 % der Studienpopulation festgestellt. Der wichtigste Risikofaktor war die Gesamtzahl der verabreichten Medikamente. Die Arzneimittelgruppen, die bei der Mehrzahl der Wechselwirkungen beteiligt waren, waren Analgetika, Herz-Kreislauf-Medikamente und gerinnungshemmende Medikamente sowie Antidepressiva. Das Risiko unerwünschte Arzneimittelwirkungen auszubilden wurde bei 53,1 % der stationären Patienten als "hoch" eingestuft. Die fünf wichtigsten unerwünschten Nebenwirkungen in dieser Patientengruppe waren Blutungen, Obstipation, anticholinerge Effekte, Sedierung und orthostatische Effekte. Potenzielle Arzneimittelwechselwirkungen sowie unerwünschte Arzneimittelwirkungen sind bei stationären dermatologischen Patienten alarmierend häufig. Bei jedem zweiten Patienten besteht die Gefahr, derartige Wechselwirkungen oder unerwünschte Nebenwirkungen zu erleiden und jeder zwanzigste Patient erhält eine Arzneimittelkombination, die nicht verabreicht werden sollte. Erhöhte Wachsamkeit ist erforderlich, um die gefährdeten Patienten zu erkennen. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  11. Zur Aktualität der identitären Ideologie : die Vordenker einer neuen rechten Internationale

    OpenAIRE

    Brumlik, Micha

    2017-01-01

    Rechtspopulistische Bewegungen machen sich zur Zeit in vielen westlichen Staaten zum Sprachrohr angeblich bisher unterdrückter Bevölkerungsgruppen und Meinungen. Die identitäre Bewegung entwickelt diesen Ansatz weiter zu einem Projekt der autoritären Staatlichkeit gegen Multikulturalismus, Islam und Einwanderung. Dabei verbindet sie ihre Kampagne für einen ethnisch geschlossen Nationalstaat mit der Kritik an der kapitalistischen Globalisierung. Mit einem Sprachduktus, der Politik emotionalisi...

  12. Sanãtana dharma / René Guénon ; tõlkinud ja kommenteerinud Haljand Udam

    Index Scriptorium Estoniae

    Guénon, René

    2004-01-01

    René Guénoni essee "Sanãtana dharma" ilmus 1949. a. ja uuesti 1989. a. raamatus "Études sur ľhindouisme" lk. 105-116 ja käsitleb mõiste "sanãtana dharma" ja "philosophia perennis" tõlgendusi ja tähendust. Esseele on lisatud põhjalik tõlkijapoolne kommentaar

  13. Zhen gan xi feng decoction, a traditional chinese herbal formula, for the treatment of essential hypertension: a systematic review of randomized controlled trials.

    Science.gov (United States)

    Xiong, Xingjiang; Yang, Xiaochen; Feng, Bo; Liu, Wei; Duan, Lian; Gao, Ao; Li, Haixia; Ma, Jizheng; Du, Xinliang; Li, Nan; Wang, Pengqian; Su, Kelei; Chu, Fuyong; Zhang, Guohao; Li, Xiaoke; Wang, Jie

    2013-01-01

    Objectives. To assess the clinical effectiveness and adverse effects of Zhen Gan Xi Feng Decoction (ZGXFD) for essential hypertension (EH). Methods. Five major electronic databases were searched up to August 2012 to retrieve any potential randomized controlled trials designed to evaluate the clinical effectiveness of ZGXFD for EH reported in any language, with main outcome measure as blood pressure (BP). Results. Six randomized trials were included. Methodological quality of the trials was evaluated as generally low. Four trials compared prescriptions based on ZGXFD with antihypertensive drugs. Meta-analysis showed that ZGXFD was more effective in BP control and TCM syndrome and symptom differentiation (TCM-SSD) scores than antihypertensive drugs. Two trials compared the combination of modified ZGXFD plus antihypertensive drugs with antihypertensive drugs. Meta-analysis showed that there is significant beneficial effect on TCM-SSD scores. However, no significant effect on BP was found. The safety of ZGXFD is still uncertain. Conclusions. ZGXFD appears to be effective in improving blood pressure and hypertension-related symptoms for EH. However, the evidence remains weak due to poor methodological quality of the included studies. More rigorous trials are warranted to support their clinical use.

  14. Correction of sub-pixel topographical effects on land surface albedo retrieved from geostationary satellite (FengYun-2D) observations

    International Nuclear Information System (INIS)

    Roupioz, L; Nerry, F; Jia, L; Menenti, M

    2014-01-01

    The Qinghai-Tibetan Plateau is characterised by a very strong relief which affects albedo retrieval from satellite data. The objective of this study is to highlight the effects of sub-pixel topography and to account for those effects when retrieving land surface albedo from geostationary satellite FengYun-2D (FY-2D) data with 1.25km spatial resolution using the high spatial resolution (30 m) data of the Digital Elevation Model (DEM) from ASTER. The methodology integrates the effects of sub-pixel topography on the estimation of the total irradiance received at the surface, allowing the computation of the topographically corrected surface reflectance. Furthermore, surface albedo is estimated by applying the parametric BRDF (Bidirectional Reflectance Distribution Function) model called RPV (Rahman-Pinty-Verstraete) to the terrain corrected surface reflectance. The results, evaluated against ground measurements collected over several experimental sites on the Qinghai-Tibetan Plateau, document the advantage of integrating the sub-pixel topography effects in the land surface reflectance at 1km resolution to estimate the land surface albedo. The results obtained after using sub-pixel topographic correction are compared with the ones obtained after using pixel level topographic correction. The preliminary results imply that, in highly rugged terrain, the sub-pixel topography correction method gives more accurate results. The pixel level correction tends to overestimate surface albedo

  15. The Adhesion of Lactobacillus salivarius REN to a Human Intestinal Epithelial Cell Line Requires S-layer Proteins.

    Science.gov (United States)

    Wang, Ran; Jiang, Lun; Zhang, Ming; Zhao, Liang; Hao, Yanling; Guo, Huiyuan; Sang, Yue; Zhang, Hao; Ren, Fazheng

    2017-03-10

    Lactobacillus salivarius REN, a novel probiotic isolated from Chinese centenarians, can adhere to intestinal epithelial cells and subsequently colonize the host. We show here that the surface-layer protein choline-binding protein A (CbpA) of L. salivarius REN was involved in adherence to the human colorectal adenocarcinoma cell line HT-29. Adhesion of a cbpA deletion mutant was significantly reduced compared with that of wild-type, suggesting that CbpA acts as an adhesin that mediates the interaction between the bacterium and its host. To identify the molecular mechanism of adhesion, we determined the crystal structure of a truncated form of CbpA that is likely involved in binding to its cell-surface receptor. The crystal structure identified CbpA as a peptidase of the M23 family whose members harbor a zinc-dependent catalytic site. Therefore, we propose that CbpA acts as a multifunctional surface protein that cleaves the host extracellular matrix and participates in adherence. Moreover, we identified enolase as the CbpA receptor on the surface of HT-29 cells. The present study reveals a new class of surface-layer proteins as well as the molecular mechanism that may contribute to the ability of L. salivarius REN to colonize the human gut.

  16. Research and Measurement of Software Complexity Based on Wuli, Shili, Renli (WSR and Information Entropy

    Directory of Open Access Journals (Sweden)

    Rong Jiang

    2015-04-01

    Full Text Available Complexity is an important factor throughout the software life cycle. It is increasingly difficult to guarantee software quality, cost and development progress with the increase in complexity. Excessive complexity is one of the main reasons for the failure of software projects, so effective recognition, measurement and control of complexity becomes the key of project management. At first, this paper analyzes the current research situation of software complexity systematically and points out existing problems in current research. Then, it proposes a WSR framework of software complexity, which divides the complexity of software into three levels of Wuli (WL, Shili (SL and Renli (RL, so that the staff in different roles may have a better understanding of complexity. Man is the main source of complexity, but the current research focuses on WL complexity, and the research of RL complexity is extremely scarce, so this paper emphasizes the research of RL complexity of software projects. This paper not only analyzes the composing factors of RL complexity, but also provides the definition of RL complexity. Moreover, it puts forward a quantitative measurement method of the complexity of personnel organization hierarchy and the complexity of personnel communication information based on information entropy first and analyzes and validates the scientificity and rationality of this measurement method through a large number of cases.

  17. Objectivity, abstraction, and the individual: the influence of Søren Kierkegaard on Paul Feyerabend.

    Science.gov (United States)

    Kidd, Ian James

    2011-03-01

    This paper explores the influence of Søren Kierkegaard upon Paul Feyerabend by examining their common criticisms of totalising accounts of human nature. Both complained that philosophical and scientific theories of human nature which were methodologically committed to objectivity and abstraction failed to capture the richness of human experience. Kierkegaard and Feyerabend argued that philosophy and the science were threatening to become obstacles to human development by imposing abstract theories of human nature and reality which denied the complexities of both. In both cases, this took the form of asserting an 'existential' criterion for the assessment of philosophical and scientific theories. Kierkegaard also made remarks upon the inappropriateness of applying natural scientific methods to human beings which Feyerabend later expanded and developed in his criticisms of the inability of the 'scientific world-view' to accommodate the values necessary to a flourishing human life. I conclude by noting some differences between Kierkegaard and Feyerabend's positions and by affirming the value of existential criticisms of scientific knowledge.

  18. PHYSICOCHEMICAL PROPERTIES AND USES OF KARACAÖREN AREA (NEVŞEHİR DIATOMITE

    Directory of Open Access Journals (Sweden)

    Ayşegül YILDIZ

    2016-12-01

    Full Text Available In this study, physicochemical properties and the area of use of diatomites that occur in association with Central Anatolian volcanism in the Karacaören region (Ürgüp country, Nevşehir are investigated. In the investigated area two stratigraphic sections were measured, one is in Quaternary lake units (K1 and another section is in the lacustrine sediments of Bayramhacılı Member within Ürgüp Formation of late Miocene-Pliocene age (K2. In order to specify physicochemical properties and the area of use of diato- mites, various analyses were carried out at the Laboratories of General Directorate of Mineral Research and Exploration including loss on ignition (at 1050 °C, XRD, amount of acid and water-insoluble matter, thermal conductivity (in the range of 101; 150 °C and ± 10 °C, XRF, pH, total porosity, specific gravity, specific surface area, pore volume, pore size, whiteness, particle size and SEM analysis. The evaluation of the analyses results showed that the studied diatomites have a commercial value and can be used directly in percolator, as filler and structuring agents and in silicate manufacturing. In addition, once processed, they can also be used as mild abrasive and cleaner in production of isolation material.

  19. René Dubos, tuberculosis, and the "ecological facets of virulence".

    Science.gov (United States)

    Honigsbaum, Mark

    2017-09-01

    Reflecting on his scientific career toward the end of his life, the French-educated medical researcher René Dubos presented his flowering as an ecological thinker as a story of linear progression-the inevitable product of the intellectual seeds planted in his youth. But how much store should we set by Dubos's account of his ecological journey? Resisting retrospective biographical readings, this paper seeks to relate the development of Dubos's ecological ideas to his experimental practices and his career as a laboratory researcher. In particular, I focus on Dubos's studies of tuberculosis at the Rockefeller Institute in the period 1944-1956-studies which began with an inquiry into the tubercle bacillus and the physiochemical determinants of virulence, but which soon encompassed a wider investigation of the influence of environmental forces and host-parasite interactions on susceptibility and resistance to infection in animal models. At the same time, through a close reading of Dubos's scientific papers and correspondence, I show how he both drew on and distinguished his ecological ideas from those of other medical researchers such as Theobald Smith, Frank Macfarlane Burnet, and Frank Fenner. However, whereas Burnet and Fenner tended to view ecological interactions at the level of populations, Dubos focused on the interface of hosts and parasites in the physiological environments of individuals. The result was that although Dubos never fully engaged with the science of ecology, he was able to incorporate ecological ideas into his thought and practices, and relate them to his holistic views on health and the natural harmony of man and his environment.

  20. Liposomal preparation by supercritical fluids technology | Zhong ...

    African Journals Online (AJOL)

    African Journal of Biotechnology ... technology (SCF) has been utilized in liposomal preparation because of its friendliness, nontoxicity to the environment and its possibility to achieve solvent-free liposomes and industrial-scale of liposome production under the conditions of current good manufacturing practice (cGMP).

  1. Von kleinen Stupsern und großen Schubsern – Politik und Ethik des Libertären Paternalismus auf dem Prüfstand

    Directory of Open Access Journals (Sweden)

    Drerup Johannes

    2016-07-01

    Full Text Available Das von Cass Sunstein und Richard Thaler ausgearbeitete Projekt eines Libertären Paternalismus stellt fraglos einen der zurzeit meistdiskutierten neopaternalistischen Theorieentwürfe dar. Als hybride Mischung zwischen Theorieprogramm, politischer Bewegung und praxis- und anwendungsorientiertem Policy-Manual, das zuweilen Züge eines populären philosophischen Lebensratgebers trägt, hat Libertärer Paternalismus viel Zuspruch, aber auch heftige Kritik auf sich gezogen, die in diesem Aufsatz auf ihre Plausibilität geprüft werden. Zu diesem Zweck geben die Autoren zunächst einen kurzen Überblick über Ausgangspunkte, Leitorientierungen und Problemvorgaben des Theorie- und Politikprogramms des Libertären Paternalismus. In einem zweiten Schritt werden zentrale (metaphorische Konzepte und Unterscheidungen des libertär paternalistischen Rationales vorgestellt und problematisiert. Daran anschließend werden drei der prominentesten Kritikpunkte an Libertärem Paternalismus auf den Prüfstand gestellt. Hierzu gehören der Manipulationseinwand, Kritiken, die sich auf grundlegende Rechtfertigungsprobleme des Libertären Paternalismus beziehen, und Einwände, die auf langfristige negative Folgen des Nudging verweisen („Slippery-Slope-Argumente“.

  2. Genetische Veränderungen an primären Prostatakarzinom-Biopsien in Korrelation zum klinischen Verlauf

    Directory of Open Access Journals (Sweden)

    Steiner T

    2002-01-01

    Full Text Available Die der Entstehung des Prostatakarzinoms zugrundeliegenden bzw. mit einem Progreß vergesellschafteten genetischen Veränderungen sind noch weitgehend unbekannt. Ziel der vorliegenden retrospektiven Untersuchung war die Erfassung genetischer Aberrationen an paraffineigebettetem Material primärer Prostatakarzinom-Biopsien und die Korrelation der Daten zum klinischen Verlauf. In 28 karzinomtragenden primären Prostatabiopsien wurden die Tumorareale gekennzeichnet. Nach Dissektion der Tumorzellen wurden die Proben mittels "comparative genomic hybridization" (CGH analysiert. Daten zum klinischen Verlauf der Patienten wurden erfaßt. Die mittlere Nachbeobachtungszeit betrug 36 Monate, alle Patienten wurden hormonablativ behandelt. 11 Patienten (39 % wiesen unter laufender Therapie einen Tumorprogreß auf. In 25 (88 % der 28 untersuchten Tumorareale konnten genetische Aberrationen detektiert werden, im Mittel fanden wir 4,8 Aberrationen je Tumor. Das Verhältnis Verlust / Zugewinn betrug 1,3 / 1. Folgende chromosomale Veränderungen wurden häufig festgestellt: Verluste von 6q in 40 %; von 8p in 32 %; von 16q in 21 %; von 18q in 21 %; Zugewinne von 8q in 32 %; von 17 in 43 %. In Korrelation zum klinischen Verlauf fand sich ein Zugewinn von 8q signifikant häufiger bei Patienten, welche im Beobachtungszeitraum einen Tumorprogreß entwickelten (64 % vs. 12 %; p = 0,0001. In der primären Tumorbiopsie waren bei progredienten Patienten im Mittel 5,3, bei Patienten ohne Tumorprogreß 3,8 Aberrationen je Tumor nachzuweisen. Unsere Ergebnisse zeigen, daß Veränderungen der Chromosomen 6q, 8, 16q, 17 und 18q regelmäßig beim Prostatakarzinom auftreten. Karzinome mit klinisch ungünstigem Verlauf weisen bereits in der primären Biopsie eine hohe genetische Instabilität auf.

  3. Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats

    DEFF Research Database (Denmark)

    Heijnen, Bart Fj; Pelkmans, Leonie Pj; Danser, Ah Jan

    2013-01-01

    This study investigated renin-angiotensin system (RAS)-induced cardiac remodeling and its reversibility in the presence and absence of high blood pressure (BP) in Cyp1a1-Ren2 transgenic inducible hypertensive rats (IHR). In IHR (pro)renin levels and BP can be dose-dependently titrated by oral...... administration of indole-3-carbinol (I3C). Young (four-weeks old) and adult (30-weeks old) IHR were fed I3C for four weeks (leading to systolic BP >200 mmHg). RAS-stimulation was stopped and animals were followed-up for a consecutive period. Cardiac function and geometry was determined echocardiographically...

  4. Mechanismen der intrinsischen Cisplatinhypersensitivität bei der testikulären Keimzelltumor-Linie NTERA-2D1

    OpenAIRE

    Alber, Christiane

    2011-01-01

    Mit Einführung von Cisplatin gelang ein Durchbruch in der Therapie testikulärer Keimzelltumore, deren Heilungsrate auf über 80% gesteigert werden konnte. Die Ursache der Hypersensitivität von Hodenkarzinomen gegenüber Cisplatin ist bis heute nicht abschließend geklärt, für die Medizin jedoch von hohem Interesse, da hieraus möglicherweise neue Ansätze für die Therapie anderer Tumorentitäten gewonnen werden könnten. In der vorliegenden Arbeit konnte die hohe Sensitivität der testikulären Keimze...

  5. The secret of René Guénon: A critical review of Guénon's traditionalism

    OpenAIRE

    Poznanović Željko

    2014-01-01

    This paper aims to present the basic principles of the doctrine of René Guénon (1886-1951), a French thinker of broad and comprehensive scope when it comes to Hinduism, Western Occult Tradition, Freemasonry, Taoism, symbolism and certain aspects of metaphysics. His teaching did not leave a mark in the mainstream of philosophy, yet it founded a whole syncretic movement known as Traditionalism or Perennialism. While Guénons doctrine is commonly either ignored or accepted as unquestionably true,...

  6. Potential effectiveness of Chinese herbal medicine Yu ping feng san for adult allergic rhinitis: a systematic review and meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Luo, Qiulan; Zhang, Claire Shuiqing; Yang, Lihong; Zhang, Anthony Lin; Guo, Xinfeng; Xue, Charlie Changli; Lu, Chuanjian

    2017-11-06

    Chinese herbal medicine formula Yu ping feng san (YPFS) is commonly used for allergic rhinitis (AR). Previous review had summarized the effectiveness and safety of YPFS, however without any subgroup analysis performed to provide detailed evidence for guiding clinical practice. YPFS was recommended for the management of AR by Chinese medicine clinical practice guideline, but the treatment duration of YPFS was also not specified. The aim of this study is to evaluate the effectiveness and safety of YPFS in treating adult AR with the most recent evidence, and attempt to specify the duration of utilisation through subgroup meta-analyses. Seven databases were searched from their inceptions to September 2017. Randomized controlled trials (RCTs) evaluating YPFS for adult AR were included. Methodological quality of studies was assessed using the Cochrane risk of bias tool. Meta-analysis and subgroup meta-analyses were conducted for evaluating the effectiveness of YPFS. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used for rating the quality of evidence. Twenty-two RCTs involving 23 comparisons were included in this review. YPFS was compared to placebo, pharmacotherapy, and used as an add-on treatment compared to pharmacotherapy. Meta-analyses were feasible for the outcomes of four individual nasal symptom scores and "effective rate". Four individual nasal symptom scores decreased after YPFS' combination treatment: itchy nose (MD-0.46, 95% CI[-0.50, -0.42]), sneezing (MD-0.41, 95% CI[-0.47, -0.35]), blocked nose (MD-0.46, 95% CI[-0.54, -0.39]) and runny nose (MD-0.42, 95% CI[-0.58, -0.26]). Based on "effective rate", meta-analysis showed that YPFS did not achieve better effect than pharmacotherapy (RR1.07, 95%CI [0.94, 1.22), but its combination with pharmacotherapy seemed more effective than pharmacotherapy alone (RR1.27, 95%CI [1.19, 1.34]) (low quality). Subgroup analysis suggested that YPFS was not superior to the second

  7. Generalized Split-Window Algorithm for Estimate of Land Surface Temperature from Chinese Geostationary FengYun Meteorological Satellite (FY-2C Data

    Directory of Open Access Journals (Sweden)

    Jun Xia

    2008-02-01

    Full Text Available On the basis of the radiative transfer theory, this paper addressed the estimate ofLand Surface Temperature (LST from the Chinese first operational geostationarymeteorological satellite-FengYun-2C (FY-2C data in two thermal infrared channels (IR1,10.3-11.3 μ m and IR2, 11.5-12.5 μ m , using the Generalized Split-Window (GSWalgorithm proposed by Wan and Dozier (1996. The coefficients in the GSW algorithmcorresponding to a series of overlapping ranging of the mean emissivity, the atmosphericWater Vapor Content (WVC, and the LST were derived using a statistical regressionmethod from the numerical values simulated with an accurate atmospheric radiativetransfer model MODTRAN 4 over a wide range of atmospheric and surface conditions.The simulation analysis showed that the LST could be estimated by the GSW algorithmwith the Root Mean Square Error (RMSE less than 1 K for the sub-ranges with theViewing Zenith Angle (VZA less than 30° or for the sub-rangs with VZA less than 60°and the atmospheric WVC less than 3.5 g/cm2 provided that the Land Surface Emissivities(LSEs are known. In order to determine the range for the optimum coefficients of theGSW algorithm, the LSEs could be derived from the data in MODIS channels 31 and 32 provided by MODIS/Terra LST product MOD11B1, or be estimated either according tothe land surface classification or using the method proposed by Jiang et al. (2006; and theWVC could be obtained from MODIS total precipitable water product MOD05, or beretrieved using Li et al.’ method (2003. The sensitivity and error analyses in term of theuncertainty of the LSE and WVC as well as the instrumental noise were performed. Inaddition, in order to compare the different formulations of the split-window algorithms,several recently proposed split-window algorithms were used to estimate the LST with thesame simulated FY-2C data. The result of the intercomparsion showed that most of thealgorithms give

  8. Co je na životě tak zvláštního? Příklad redukcionismu René Descarta (What is so special about life? The example of René Descartes‘ reductionism

    Directory of Open Access Journals (Sweden)

    Vladimír Vodička

    2017-03-01

    Full Text Available History of philosophy offers many examples capable of informing discussions related to questions, topics and problems, which are actual for both philosophy and particular scientific fields. Explanation of the nature of life is such a topic. Although current debates have been paying attention to the impact of scientific findings on our understanding of the phenomenon of life, the very definition of life falls in to the continuum between philosophy and science, the endeavor to capture origin of life and possibilities of creating artificial life bring up both theoretical and practical questions alike. In this paper we approach to the analysis of the standpoint of one of the most important philosophical authorities of modern philosophy, René Descartes. By the analysis of his approach to the nature of life we try to amend his reception and intellectual legacy of not so well appreciated part of his works.

  9. Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet

    Czech Academy of Sciences Publication Activity Database

    Vaněčková, Ivana; Dobešová, Zdenka; Kuneš, Jaroslav; Vernerová, Z.; Zicha, Josef

    2015-01-01

    Roč. 33, č. 1 (2015), s. 161-169 ISSN 0263-6352 R&D Projects: GA ČR(CZ) GAP304/12/0259 Institutional support: RVO:67985823 Keywords : endothelin * high-salt intake * hypertension * Ren-2 Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 5.062, year: 2015

  10. Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model.

    Science.gov (United States)

    Borgna, Vincenzo; Villegas, Jaime; Burzio, Verónica A; Belmar, Sebastián; Araya, Mariela; Jeldes, Emanuel; Lobos-González, Lorena; Silva, Verónica; Villota, Claudio; Oliveira-Cruz, Luciana; Lopez, Constanza; Socias, Teresa; Castillo, Octavio; Burzio, Luis O

    2017-07-04

    Knockdown of antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptosis in several human and mouse tumor cell lines, but not normal cells, suggesting this approach for a selective therapy against different types of cancer. Here we show that in vitro knockdown of murine ASncmtRNAs induces apoptotic death of mouse renal adenocarcinoma RenCa cells, but not normal murine kidney epithelial cells. In a syngeneic subcutaneous RenCa model, treatment delayed and even reversed tumor growth. Since the subcutaneous model does not reflect the natural microenviroment of renal cancer, we used an orthotopic model of RenCa cells inoculated under the renal capsule. These studies showed inhibition of tumor growth and metastasis. Direct metastasis assessment by tail vein injection of RenCa cells also showed a drastic reduction in lung metastatic nodules. In vivo treatment reduces survivin, N-cadherin and P-cadherin levels, providing a molecular basis for metastasis inhibition. In consequence, the treatment significantly enhanced mouse survival in these models. Our results suggest that the ASncmtRNAs could be potent and selective targets for therapy against human renal cell carcinoma.

  11. Reference: 759 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 759 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u18434608i Guan Yue-Feng...s. 2 852-63 18434608 2008 Jun Plant physiology Gao Ju-Fang|Guan Yue-Feng|Huang Xue-Yong|Yang Zhong-Nan|Zhang Hong-Xia|Zhu Jun

  12. Une lettre inédite de René Dumesnil à Marcel Proust du 19 janvier 1920

    Directory of Open Access Journals (Sweden)

    Pyra Wise

    2009-10-01

    Full Text Available PrésentationJusqu’à ce jour le lecteur de la correspondance de Proust connaissait l’existence d’une lettre de René Dumesnil félicitant Proust pour son article « À propos du "style" de Flaubert », paru dans la Nouvelle Revue française, le 1er janvier 1920. Mais il ne pouvait en lire qu’un extrait de moins de deux phrases, non daté, puisque l’éditeur de cette correspondance, Philip Kolb, n’avait pas eu accès à la lettre autographe et s’était vu obligé de reprendre le très court extrait publié e...

  13. The pedagogical work of the sculptor René Valdés Cedeño (1916-1976

    Directory of Open Access Journals (Sweden)

    Sonia Tellez-Vigueaux

    2017-12-01

    Full Text Available René Valdés Cedeño (1916-1976 was a Havana sculptor who made most of his artistic production in Santiago de Cuba. Pedagogue par excellence held various positions at the Provincial School of Plastic Arts José Joaquín Tejada. His work as a teacher of generations of sculptors earned him the recognition of his students and the Ministry of Education. Author of important works such as the Spirit of the Mountain, located in the Puerto de Boniato, Monument of the Abel Santamaría Square Park, among others. He had great skill with the chisel, he works stone and marble. However, his life and work has been little studied and deepened. So this article aims to show the pedagogical work of this artist.

  14. The Nothingness of the Anguish in Søren Kierkegaard’s work as Modernity’s Infernal Redemption

    Directory of Open Access Journals (Sweden)

    Francisc-Norbert Ormeny

    2015-09-01

    Full Text Available The intention of this short study is to discuss the reverberations of Søren Kierkegaard’s philosophical considerations on anguish and on void in the context of the latest postmodern theoretical trends (Ben Woodard’s dark vitalism, by presenting the mechanisms by means of which the anguish gets to produce an “existential switch” which extracts the individual from the register of disintegration and introduces him into the register of the project (Heideggerianly speaking. I will try to demonstrate the compatibility between the structures of the late modernity and the Kierkegaardian vision on tension and on paradox, and will I will attempt to connect the possible findings to the relevant and congenial phenomenological, existentialist and aesthetic theories or set of theories circulating in today’s exegetical canon

  15. Association of the polymorphism 12109g>A from the REN gene as a risk factor for preterm birth

    Directory of Open Access Journals (Sweden)

    Irám P Rodríguez-Sánchez

    2016-11-01

    Full Text Available Introduction: Preterm birth is the most important cause of neonatal mortality and morbidity. It is a multifactorial disease with different etiologies, including genetic factors. Genetic variability is represented by single nucleotide polymorphisms (SNPs in genes of proteins involved in the contractile activity. We determine the association between SNP 12109G> A in REN associated with preterm birth and premature rupture of membrane. Materials and methods: A study of cases (N=112, 22–36 weeks of gestation; mean: 31, 95% confidence interval 30.7–32.2 and controls (N=66; 38–40 weeks of gestation from the last menstrual period; mean: 39.8, 95% confidence interval 38.9–39.4 was performed. Genomic DNA was isolated in all patients from peripheral blood. The SNP 12109G> A (Mbo I in REN was typified by PCR-restriction fragment length polymorphism. Results: A significant difference in the case group for the SNP 12109G>A was observed. The A allele was increased in women with preterm birth (81% cases vs. 15% control, p A has odds ratio 6.62 (95% confidence interval 3.14–14.15, which means a high risk of preterm birth/premature rupture of membrane in presence of allele A, both in homozygotes and in heterozygotes. Conclusion: Allelic frequency of A of SNP 12109G>A was higher in women with preterm birth than in women with normal vaginal delivery and could be considered a risk factor.

  16. Estrogen Therapy, Independent of Timing, Improves Cardiac Structure and Function in Oophorectomized mRen2.Lewis Rats

    Science.gov (United States)

    Jessup, Jewell A.; Wang, Hao; MacNamara, Lindsay M.; Presley, Tennille D.; Kim-Shapiro, Daniel B.; Zhang, Lili; Chen, Alex F.; Groban, Leanne

    2013-01-01

    Objective mRen2.Lewis Rats exhibit exacerbated increases in blood pressure, left ventricular (LV) remodeling, and diastolic impairment following the loss of estrogens. In this same model, depletion of estrogens has marked effects on the cardiac biopterin profile concomitant with suppressed nitric oxide (NO) release. With respect to the establishment of overt systolic hypertension after oophorectomy (OVX), we assessed the effects of timing chronic 17 β-estradiol (E2) therapy on myocardial function, structure, and the cardiac NO system. Methods Oophrectomy (OVX; n=24) or sham-operation (Sham; n=13) was performed in 4-week-old, female mRen2.Lewis rats. Following randomization, OVX rats received E2 immediately (OVX + early E2; n=7), E2 at 11 weeks of age (OVX + late E2 N=8), or no E2 at all (OVX N=9). Results Early E2 was associated with lower body weight, less hypertension-related cardiac remodeling, and decreased LV filling pressure compared to OVX rats without E2 supplementation. Late E2 similarly attenuated the adverse effects of ovarian hormone loss on tissue-Doppler derived LV filling pressures and perivascular fibrosis, and significantly improved myocardial relaxation, or mitral annular velocity (e′). Early and late exposure to E2 decreased dihydrobiopterin, but only late E2 yielded significant increases in cardiac nitrite concentrations. Conclusions Although there were some similarities between early and late E2 treatment on preservation of diastolic function and cardiac structure after OVX, the lusitropic potential of E2 was most consistent with late supplementation. The cardioprotective effects of late E2 were independent of blood pressure and may have occurred through regulation of cardiac biopterins and NO production. PMID:23481117

  17. Interview with René Yáñez, artist, co-founder of the Galería de la Raza, San Francisco, CA, USA, August 13, 2001 Entretien avec René Yáñez, artiste, co-fondateur de la Galería de la Raza, San Francisco, CA, Etats-Unis

    Directory of Open Access Journals (Sweden)

    Gérard Selbach

    2009-10-01

    Full Text Available René Yáñez is an all-round visual artist and visionary, now in his sixties. He came out of the Chicano movement of the 70’s and was instrumental in founding the Galería de la Raza in the Mission district of San Francisco. He remained some fifteen years as its director, curating exhibitions, directing and promoting emerging artists of all kinds. He then worked as director of cultural programming at the Mexican Museum until its closure. René Yáñez co-produced Mexican performance artist Astrid H...

  18. 18th May 2011 - Chinese State Administration of Foreign Experts Affairs (SAFEA) Deputy Director-General M. LU (State Council of China) in the ATLAS visitors centre with Collaboration Deputy Spokesperson A. Lankford and Collaboration member Z. Ren.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    18th May 2011 - Chinese State Administration of Foreign Experts Affairs (SAFEA) Deputy Director-General M. LU (State Council of China) in the ATLAS visitors centre with Collaboration Deputy Spokesperson A. Lankford and Collaboration member Z. Ren.

  19. Baseline characteristics of patients with heart failure and preserved ejection fraction included in the Karolinska Rennes (KaRen) study.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars H; Oger, Emmanuel; Hage, Camilla; Persson, Hans; Reynaud, Amélie; Ennezat, Pierre-Vladimir; Bauer, Fabrice; Sportouch-Dukhan, Catherine; Drouet, Elodie; Daubert, Jean-Claude; Linde, Cecilia

    2014-02-01

    Karolinska Rennes (KaRen) is a prospective observational study to characterize heart failure patients with preserved ejection fraction (HFpEF) and to identify prognostic factors for long-term mortality and morbidity. To report characteristics and echocardiography at entry and after 4-8 weeks of follow-up. Patients were included following an acute heart failure presentation with B-type natriuretic peptide (BNP)>100 ng/L or N-terminal pro-BNP (NT-proBNP)>300 ng/L and left ventricular ejection fraction (LVEF)>45%. The mean ± SD age of 539 included patients was 77 ± 9 years and 56% were women. Patient history included hypertension (78%), atrial tachyarrhythmia (44%), prior heart failure (40%) and anemia (37%), but left bundle branch block was rare (3.8%). Median NT-proBNP was 2448 ng/L (n=438), and median BNP 429 ng/L (n=101). Overall, 101 patients did not return for the follow-up visit, including 13 patients who died (2.4%). Apart from older age (80 ± 9 vs. 76 ± 9 years; P=0.006), there were no significant differences in baseline characteristics between patients who did and did not return for follow-up. Mean LVEF was lower at entry than follow-up (56% vs. 62%; P<0.001). At follow-up, mean E/e' was 12.9 ± 6.1, left atrial volume index 49.4±17.8mL/m(2). Mean global left ventricular longitudinal strain was -14.6 ± 3.9%; LV mass index was 126.6 ± 36.2g/m(2). Patients in KaRen were old with slight female dominance and hypertension as the most prevalent etiological factor. LVEF was preserved, but with increased LV mass and depressed LV diastolic and longitudinal systolic functions. Few patients had signs of electrical dyssynchrony (ClinicalTrials.gov.- NCT00774709). Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  20. Celebrating Two Centuries since the Invention of the Stethoscope. René Théophile Hyacinthe Laënnec (1781-1826).

    Science.gov (United States)

    Tomos, Ioannis; Karakatsani, Anna; Manali, Effrosyni D; Papiris, Spyros A

    2016-10-01

    René Théophile Hyacinthe Laënnec (1781-1826), a French physician, is considered one of the pioneers of respiratory medicine. His contribution to the invention of the stethoscope and to the development of clinical auscultation played a key role in the progress of the diagnosis of chest diseases. Almost two centuries after his invention of the stethoscope, his achievements continue to be widely appreciated and used by modern physicians in current pulmonology.

  1. Clinical Efficacy of Traditional Chinese Medicine, Suan Zao Ren Tang, for Sleep Disturbance during Methadone Maintenance: A Randomized, Double-Blind, Placebo-Controlled Trial

    OpenAIRE

    Chan, Yuan-Yu; Chen, Yi-Hung; Yang, Szu-Nian; Lo, Wan-Yu; Lin, Jaung-Geng

    2015-01-01

    Methadone maintenance therapy is an effective treatment for opiate dependence, but more than three-quarters of persons receiving the treatment report sleep quality disturbances. In this double-blind, randomized, controlled trial, we recruited 90 individuals receiving methadone for at least one month who reported sleep disturbances and had Pittsburgh Sleep Quality Index (PSQI) scores > 5. The purpose of this study was to determine whether Suan Zao Ren Tang, one of the most commonly prescribed ...

  2. Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

    OpenAIRE

    Hu, Lin-lin; Zhang, Xin; Liu, Wen-juan; Li, Mei; Zhang, Yong-hua

    2015-01-01

    Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT) and Zhi Zi Chi Tang (ZZCT; SZR-ZZC) for improving sleep quality and anxiety states with four indices of Polysomnography (PSG), the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), and the Self Rating Anxiety Scale (SAS). Methods. A randomized, parallel-controlled trial...

  3. Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats

    Czech Academy of Sciences Publication Activity Database

    Vaňourková, Z.; Kramer, H. J.; Husková, Z.; Červenka, L.; Vaněčková, Ivana

    2010-01-01

    Roč. 59, č. 3 (2010), s. 339-345 ISSN 0862-8408 Grant - others:GA ČR(CZ) GA305/07/0167; GA ČR(CZ) GC305/07/J004 Institutional research plan: CEZ:AV0Z50110509 Keywords : Ren- rats * albuminuria * RAS blockade Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 1.646, year: 2010

  4. RUN1 and REN1 Pyramiding in Grapevine (Vitis vinifera cv. Crimson Seedless) Displays an Improved Defense Response Leading to Enhanced Resistance to Powdery Mildew (Erysiphe necator)

    Science.gov (United States)

    Agurto, Mario; Schlechter, Rudolf O.; Armijo, Grace; Solano, Esteban; Serrano, Carolina; Contreras, Rodrigo A.; Zúñiga, Gustavo E.; Arce-Johnson, Patricio

    2017-01-01

    Fungal pathogens are the cause of the most common diseases in grapevine and among them powdery mildew represents a major focus for disease management. Different strategies for introgression of resistance in grapevine are currently undertaken in breeding programs. For example, introgression of several resistance genes (R) from different sources for making it more durable and also strengthening the plant defense response. Taking this into account, we cross-pollinated P09-105/34, a grapevine plant carrying both RUN1 and REN1 pyramided loci of resistance to Erysiphe necator inherited from a pseudo-backcrossing scheme with Muscadinia rotundifolia and Vitis vinifera ‘Dzhandzhal Kara,’ respectively, with the susceptible commercial table grape cv. ‘Crimson Seedless.’ We developed RUN1REN1 resistant genotypes through conventional breeding and identified them by marker assisted selection. The characterization of defense response showed a highly effective defense mechanism against powdery mildew in these plants. Our results reveal that RUN1REN1 grapevine plants display a robust defense response against E. necator, leading to unsuccessful fungal establishment with low penetration rate and poor hypha development. This resistance mechanism includes reactive oxygen species production, callose accumulation, programmed cell death induction and mainly VvSTS36 and VvPEN1 gene activation. RUN1REN1 plants have a great potential as new table grape cultivars with durable complete resistance to E. necator, and are valuable germplasm to be included in grape breeding programs to continue pyramiding with other sources of resistance to grapevine diseases. PMID:28553300

  5. Einfluß einer In-vitro- und In-vivo-Cholesterol-Modulation in Hirnmembranen auf die zellulären Effekte von Amyloid-beta-Peptid

    OpenAIRE

    Kirsch, Christopher

    2003-01-01

    Die exzessive Bildung und Ablagerung von aggregiertem Amyloid beta-Peptid im Gehirn von Alzheimer Patienten wird allgemein als zentrales Ereignis im Rahmen des Neurodegenerationsprozesses der Alzheimer Demenz betrachtet. Der Amyloid-Stoffwechsel ist dabei in sehr vielfältiger Weise mit dem zellulären Cholesterol-Stoffwechsel verknüpft. Hohe Cholesterolspiegel in spezifischen Membrandomänen wie Lipid-Rafts forcieren sehr wahrscheinlich die zelluläre Produktion als auch die Fibrillogenese von A...

  6. Clinical Efficacy of Traditional Chinese Medicine, Suan Zao Ren Tang, for Sleep Disturbance during Methadone Maintenance: A Randomized, Double-Blind, Placebo-Controlled Trial

    Science.gov (United States)

    Chan, Yuan-Yu; Chen, Yi-Hung; Yang, Szu-Nian; Lo, Wan-Yu; Lin, Jaung-Geng

    2015-01-01

    Methadone maintenance therapy is an effective treatment for opiate dependence, but more than three-quarters of persons receiving the treatment report sleep quality disturbances. In this double-blind, randomized, controlled trial, we recruited 90 individuals receiving methadone for at least one month who reported sleep disturbances and had Pittsburgh Sleep Quality Index (PSQI) scores > 5. The purpose of this study was to determine whether Suan Zao Ren Tang, one of the most commonly prescribed traditional Chinese medications for treatment of insomnia, improves subjective sleep among methadone-maintained persons with disturbed sleep quality. Ninety patients were randomly assigned to intervention group (n = 45) and placebo group (n = 45), and all participants were analyzed. Compared with placebo treatment, Suan Zao Ren Tang treatment for four weeks produced a statistically significant improvement in the mean total PSQI scores (P = 0.007) and average sleep efficiency (P = 0.017). All adverse events (e.g., lethargy, diarrhea, and dizziness) were mild in severity. Suan Zao Ren Tang is effective for improving sleep quality and sleep efficiency among methadone-maintained patients with sleep complaints. PMID:26346534

  7. Clinical Efficacy of Traditional Chinese Medicine, Suan Zao Ren Tang, for Sleep Disturbance during Methadone Maintenance: A Randomized, Double-Blind, Placebo-Controlled Trial

    Directory of Open Access Journals (Sweden)

    Yuan-Yu Chan

    2015-01-01

    Full Text Available Methadone maintenance therapy is an effective treatment for opiate dependence, but more than three-quarters of persons receiving the treatment report sleep quality disturbances. In this double-blind, randomized, controlled trial, we recruited 90 individuals receiving methadone for at least one month who reported sleep disturbances and had Pittsburgh Sleep Quality Index (PSQI scores > 5. The purpose of this study was to determine whether Suan Zao Ren Tang, one of the most commonly prescribed traditional Chinese medications for treatment of insomnia, improves subjective sleep among methadone-maintained persons with disturbed sleep quality. Ninety patients were randomly assigned to intervention group (n=45 and placebo group (n=45, and all participants were analyzed. Compared with placebo treatment, Suan Zao Ren Tang treatment for four weeks produced a statistically significant improvement in the mean total PSQI scores (P=0.007 and average sleep efficiency (P=0.017. All adverse events (e.g., lethargy, diarrhea, and dizziness were mild in severity. Suan Zao Ren Tang is effective for improving sleep quality and sleep efficiency among methadone-maintained patients with sleep complaints.

  8. The Impact of Vocational Schools on the Regional Development Akören Ali Rıza Ercan Vocational School Example

    Directory of Open Access Journals (Sweden)

    Refika Atalay

    2017-07-01

    Full Text Available The regional development difference which has globally become a major problem even for developing countries is one of important problems of Turkey's economy. The regional dualism in the country's economy brings with many economic and social problems such as the immigration, the income inequality, the unplanned urbanization etc. The vocational schools established generally in localities less than ten thousand people contribute to remove the development difference of these localities by providing social and economic benefits as well as by training skilled staff to the locality where they are located. In this study we investigated the impact of vocational schools in the removal of the regional development difference and we made use of primary and secondary sources. Firstly, we scanned the literatures concerning this study, then we made survey with the students which study in Akören Ali Riza Ercan Vocational School. By taking the 5% significance level and the 5% margin of error into consideration in this study we used the SPSS for Windows statistics program in the evaluation of data taken as 317 students sample among the main body of 1,240 students. We tried to present solution proposals by studying the expectations and problems of the students as well as the contribution of the Akören Ali Riza Ercan Vocational School to the development of Akören district.

  9. Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

    Science.gov (United States)

    Yeh, Chia-Hao; Arnold, Christof K.; Chen, Yen-Hui; Lai, Jung-Nein

    2011-01-01

    Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT) in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI) and the World Health Organization quality of life (WHOQOL). Sixty-seven climacteric women with sleep difficulty intending to treat received SZRT at a rate of 4.0 g, thrice daily for four weeks (MRS < 16, n = 34; MRS ≥ 16, n = 33). After taking into account potential confounding factors, the mean PSQI total scores had fallen from 13.0 (±2.9) to 9.0 (±3.2) (95% confidence interval −4.93, −3.10). Further analyses showed that SZRT produced superior benefit of daytime dysfunction in women with severe menopausal symptoms (MRS ≥ 16). There were three of the withdrawals involved treatment-related adverse events (stomachache, diarrhea, and dizziness). Excluding women with a past history of stomachache, diarrhea, or dizziness, four weeks of therapy with SZRT appears to be a relatively safe and effective short-term therapeutic option in improving daytime function of climacteric women with poor sleep quality. PMID:21660310

  10. Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

    Directory of Open Access Journals (Sweden)

    Chia-Hao Yeh

    2011-01-01

    Full Text Available Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI and the World Health Organization quality of life (WHOQOL. Sixty-seven climacteric women with sleep difficulty intending to treat received SZRT at a rate of 4.0 g, thrice daily for four weeks (MRS<16, n=34; MRS≥16, n=33. After taking into account potential confounding factors, the mean PSQI total scores had fallen from 13.0 (±2.9 to 9.0 (±3.2 (95% confidence interval −4.93, −3.10. Further analyses showed that SZRT produced superior benefit of daytime dysfunction in women with severe menopausal symptoms (MRS≥16. There were three of the withdrawals involved treatment-related adverse events (stomachache, diarrhea, and dizziness. Excluding women with a past history of stomachache, diarrhea, or dizziness, four weeks of therapy with SZRT appears to be a relatively safe and effective short-term therapeutic option in improving daytime function of climacteric women with poor sleep quality.

  11. A proposal to enhance Engineering education in biology and Medicine by following the legacy of René Favaloro.

    Science.gov (United States)

    Armentano, Ricardo L; Cardelino, Juan; Wray, Sandra; Cymberknop, Leandro J; Kun, Luis

    2015-01-01

    The synergy amongst Engineering, Medicine and Biology evolves as fast as these disciplines. We propose to articulate these specialties based on the premise that new professionals must face different situations or crisis due to the so-called islands of excellence. René Favaloro focused his work and struggles against poverty, since malnutrition and environmental degradation may increase the propensity to cardiovascular diseases. Doctor Favaloro has dedicated, throughout his career, a considerable amount of time to prepare and qualify a research group, aware of the importance that an adequate working environment has over the final results. He created a team of young students, engineers, medical doctors, physicists, mathematicians and other specialists. He centered his attention on human resources, in order to disseminate his latest advances in Biology, Medicine and Engineering. We are revising the programs of biomedical engineering education and the application of new pedagogic paradigms, where critical thinking is the key: a holistic challenge that consists of a new way of learning, innovating, communicating and shearing, with a creative attitude that represents quality of perception.

  12. The secret of René Guénon: A critical review of Guénon's traditionalism

    Directory of Open Access Journals (Sweden)

    Poznanović Željko

    2014-01-01

    Full Text Available This paper aims to present the basic principles of the doctrine of René Guénon (1886-1951, a French thinker of broad and comprehensive scope when it comes to Hinduism, Western Occult Tradition, Freemasonry, Taoism, symbolism and certain aspects of metaphysics. His teaching did not leave a mark in the mainstream of philosophy, yet it founded a whole syncretic movement known as Traditionalism or Perennialism. While Guénons doctrine is commonly either ignored or accepted as unquestionably true, a critical approach to it is very rare, especially criticism of the logical coherence of the system itself. Although Guénon was not a transparently systematic thinker, his own beliefs just like any other cannot be self-contradictory. A special attention is given to the contradiction of his doctrine with Islam despite the fact that Guénon was a declared Muslim. In this paper we have particularly shown socio-political implications of Guénons doctrine supporting our attitudes by both Guénons own statements and the statements of his supporters as well as critics ranging from moderate to the most severe ones. We hope we have shown that in his doctrine there is a hidden coherent system that leads to conclusions and objectives that are precisely determined regardless of apparent contradictions.

  13. Diatom community and palaeoenvironmental properties of Karacaören diatomite deposits (Nevşehir, Central Anatolia, Turkey)

    Science.gov (United States)

    Yıldız, Ayşegül; Gürel, Ali; Dursun, Yusuf Gökhan

    2017-10-01

    The diatom community and palaeoenvironmental properties of volcano genetic diatomite deposits that outcrop in the Karacaören (Nevşehir) area are described. Two stratigraphic sections were measured in the study area. One of these sections was measured in Quaternary lake units (K1), and the other in lacustrine sediments of the late Miocene-Pliocene Ürgüp Formation's Bayramhacılı Member (K2). According to stratigraphic and chemical characteristics of the sections, two distinct paleogeographic domains were determined in the study area. One of these, the shallow lacustrine to fluvial area (Quaternary) which is represented by an alternating sequence of diatomite, silt/mud, and tuffite. The other was the deeper lacustrine stage (late Miocene) which is represented by diatomites with some interbedded mud facies, chert and volcanics. From the diatomite samples of these sections, twenty-five species of 10 different diatom genera were identified. When evaluated together, the ecological properties and the distribution of numerical values of the determined diatom genera and species, showed that the study area's diatomite was generally deposited in shallow, high temperature, nutrient-rich water, where nitrogen and phosphorus were abundant and which was an alkaline (pH > 7) freshwater lake environment. Over time the pH value of the environment decreased (pH < 7), and the environment became acidic.

  14. Strategies for RUN1 Deployment Using RUN2 and REN2 to Manage Grapevine Powdery Mildew Informed by Studies of Race Specificity.

    Science.gov (United States)

    Feechan, Angela; Kocsis, Marianna; Riaz, Summaira; Zhang, Wei; Gadoury, David M; Walker, M Andrew; Dry, Ian B; Reisch, Bruce; Cadle-Davidson, Lance

    2015-08-01

    The Toll/interleukin-1 receptor nucleotide-binding site leucine-rich repeat gene, "resistance to Uncinula necator 1" (RUN1), from Vitis rotundifolia was recently identified and confirmed to confer resistance to the grapevine powdery mildew fungus Erysiphe necator (syn. U. necator) in transgenic V. vinifera cultivars. However, sporulating powdery mildew colonies and cleistothecia of the heterothallic pathogen have been found on introgression lines containing the RUN1 locus growing in New York (NY). Two E. necator isolates collected from RUN1 vines were designated NY1-131 and NY1-137 and were used in this study to inform a strategy for durable RUN1 deployment. In order to achieve this, fitness parameters of NY1-131 and NY1-137 were quantified relative to powdery mildew isolates collected from V. rotundifolia and V. vinifera on vines containing alleles of the powdery mildew resistance genes RUN1, RUN2, or REN2. The results clearly demonstrate the race specificity of RUN1, RUN2, and REN2 resistance alleles, all of which exhibit programmed cell death (PCD)-mediated resistance. The NY1 isolates investigated were found to have an intermediate virulence on RUN1 vines, although this may be allele specific, while the Musc4 isolate collected from V. rotundifolia was virulent on all RUN1 vines. Another powdery mildew resistance locus, RUN2, was previously mapped in different V. rotundifolia genotypes, and two alleles (RUN2.1 and RUN2.2) were identified. The RUN2.1 allele was found to provide PCD-mediated resistance to both an NY1 isolate and Musc4. Importantly, REN2 vines were resistant to the NY1 isolates and RUN1REN2 vines combining both genes displayed additional resistance. Based on these results, RUN1-mediated resistance in grapevine may be enhanced by pyramiding with RUN2.1 or REN2; however, naturally occurring isolates in North America display some virulence on vines with these resistance genes. The characterization of additional resistance sources is needed to identify

  15. Functional characterization of the origin of replication of pRN1 from Sulfolobus islandicus REN1H1.

    Directory of Open Access Journals (Sweden)

    Chijioke J Joshua

    Full Text Available Plasmid pRN1 from Sulfolobus islandicus REN1H1 is believed to replicate by a rolling circle mechanism but its origin and mechanism of replication are not well understood. We sought to create minimal expression vectors based on pRN1 that would be useful for heterologous gene expression in S. acidocaldarius, and in the process improve our understanding of the mechanism of replication. We constructed and transformed shuttle vectors that harbored different contiguous stretches of DNA from pRN1 into S. acidocaldarius E4-39, a uracil auxotroph. A 232-bp region 3' of orf904 was found to be critical for pRN1 replication and is therefore proposed to be the putative origin of replication. This 232-bp region contains a 100-bp stem-loop structure believed to be the double-strand origin of replication. The loop of the 100-bp structure contains a GTG tri-nucleotide motif, a feature that was previously reported to be important for the primase activity of Orf904. This putative origin and the associated orf56 and orf904 were identified as the minimal replicon of pRN1 because transformants of plasmids lacking any of these three features were not recovered. Plasmids lacking orf904 and orf56 but harboring the putative origin were transformable when orf904 and orf56 were provided in-trans; a 75-bp region 5' of the orf904 start codon was found to be essential for this complementation. Detailed knowledge of the pRN1 origin of replication will broaden the application of the plasmid as a genetic tool for Sulfolobus species.

  16. Reanalysis of multi-temporal aerial images of Storglaciären, Sweden (1959–99 – Part 1: Determination of length, area, and volume changes

    Directory of Open Access Journals (Sweden)

    W. Haeberli

    2010-09-01

    Full Text Available Storglaciären, located in the Kebnekaise massif in northern Sweden, has a long history of glaciological research. Early photo documentations date back to the late 19th century. Measurements of front position variations and distributed mass balance have been carried out since 1910 and 1945/46, respectively. In addition to these in-situ measurements, aerial photographs have been taken at decadal intervals since the beginning of the mass balance monitoring program and were used to produce topographic glacier maps. Inaccuracies in the maps were a challenge to early attempts to derive glacier volume changes and resulted in major differences when compared to the direct glaciological mass balances. In this study, we reanalyzed dia-positives of the original aerial photographs of 1959, -69, -80, -90 and -99 based on consistent photogrammetric processing. From the resulting digital elevation models and orthophotos, changes in length, area, and volume of Storglaciären were computed between the survey years, including an assessment of related errors. Between 1959 and 1999, Storglaciären lost an ice volume of 19×106 m3, which corresponds to a cumulative ice thickness loss of 5.69 m and a mean annual loss of 0.14 m. This ice loss resulted largely from a strong volume loss during the period 1959–80 and was partly compensated during the period 1980–99. As a consequence, the glacier shows a strong retreat in the 1960s, a slowing in the 1970s, and pseudo-stationary conditions in the 1980s and 1990s.

  17. Entwicklung einer Methode zur monetären Bewertung des Wassers für ein Unternehmen unter Einbeziehung des Wasser-Fußabdrucks

    OpenAIRE

    Hentschel, Nora

    2011-01-01

    Wassernutzung und Abbau der Frischwasser-Ressourcen sind heutzutage ein Thema, das als so wichtig wahrgenommen wird wie der Klimawandel. Wasser wird somit zunehmend Auswirkungen auf den ökonomischen Wert von Unternehmen haben. Ziel der vorliegenden Arbeit ist es, den monetären Wert des Wassers mithilfe des Wasser-Fußabdrucks zu bestimmen. Hierfür werden nach einer kurzen Einführung in Kapitel 2 der ökologische Fußabdruck, der CO2-Fußabdruck und der Wasser-Fußabdruck kurz vorgestellt und in...

  18. Factores de riesgo del intento suicida en adolescentes del policlínico René Vallejo de Bayamo

    Directory of Open Access Journals (Sweden)

    Idelis Fedeslinda Arias de la Torre

    2015-01-01

    Full Text Available El suicidio, además de constituir un drama de la existencia humana, en muchos países es un problema de salud. El objetivo de esta investigación es identificar los factores de riesgo, asociados al intento suicida en adolescentes del policlínico “René Vallejo” del municipio de Bayamo en el año 2013. Se realizó un estudio de casos y controles, utilizando como universo los 43 casos que realizaron intento suicida en ese año. El grupo de casos fueron 37 adolescentes que realizaron el intento suicida y el de control, 74 adolescentes que fueron seleccionados a razón de 1:2, quedando conformado por aquellos adolescentes con características análogas a los primeros, pero que nunca intentaron suicidarse, pareados por edad, sexo y barrio. Predominó el sexo femenino, las edades de 16 a 19 años y los que cursan estudios preuniversitarios. La ideación suicida se observó en el 100 % de los casos. El antecedente familiar de depresión elevó a más de catorce veces el riesgo; las malas relaciones con los padres eleva a más de diez veces el riesgo; en los problemas de pareja a más de veinte veces; las malas relaciones con los compañeros aumenta el riesgo a más de treinta veces y el antecedente de suicidio en la familia eleva a más de cinco veces el riesgo suicida; concluyendo que los factores de riesgo con mayor asociación estadística al intento suicida fueron la ideación suicida, la ansiedad, la depresión en la familia, las malas relaciones con los padres, problemas con la pareja, las malas relaciones con los compañeros y el antecedente de suicidio consumado en la familia

  19. Copeptin in patients with heart failure and preserved ejection fraction: a report from the prospective KaRen-study.

    Science.gov (United States)

    Hage, Camilla; Lund, Lars H; Donal, Erwan; Daubert, Jean-Claude; Linde, Cecilia; Mellbin, Linda

    2015-01-01

    Underlying mechanisms of heart failure (HF) with preserved ejection fraction (HFPEF) remain unknown. We explored copeptin, a biomarker of the arginine vasopressin system, hypothesising that copeptin in HFPEF is elevated, associated with diastolic dysfunction and N-terminal pro-brain natriuretic peptide (NT-proBNP) and predictive of HF hospitalisation and mortality. In a prospective observational substudy of the The Karolinska Rennes (KaRen) 86 patients with symptoms of acute HF and ejection fraction (EF) ≥45% were enrolled. After 4-8 weeks, blood sampling and echocardiography was performed. Plasma-copeptin was analysed in 86 patients and 62 healthy controls. Patients were followed in median 579 days (quartile 1; quartile 3 (Q1;Q3) 276;1178) regarding the composite end point all-cause mortality or HF hospitalisation. The patients with HFPEF had higher copeptin levels, median 13.56 pmol/L (Q1;Q3 8.56;20.55) than controls 5.98 pmol/L (4.15;9.42; p<0.001). Diastolic dysfunction, assessable in 75/86 patients, was present in 45 and absent in 30 patients. Copeptin did not differ regarding diastolic dysfunction and did not correlate with cardiac function but with NT-proBNP (r=0.223; p value=0.040). In univariate Cox regression analysis log copeptin predicted the composite end point (HR 1.56 (95% CI 1.03 to 2.38; p value=0.037)) but not after adjusting for NT-proBNP (HR 1.39 (95% CI 0.91 to 2.12; p value=0.125)). In the present patients with HFPEF, copeptin is elevated, correlates with NT-proBNP but not markers of diastolic dysfunction, and has prognostic implications, however blunted after adjustment for NT-proBNP. The HFPEF pathophysiology may be better reflected by markers of neurohormonal activation than by diastolic dysfunction. ClinicalTrials.gov NCT00774709.

  20. Value of exercise echocardiography in heart failure with preserved ejection fraction: a substudy from the KaRen study.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars H; Oger, Emmanuel; Reynaud, Amélie; Schnell, Frédéric; Persson, Hans; Drouet, Elodie; Linde, Cecilia; Daubert, Claude

    2016-01-01

    KaRen is a multicentre study designed to characterize and follow patients with heart failure and preserved ejection fraction (HFpEF). In a subgroup of patients with clinical signs of congestion but left ventricular ejection fraction (LVEF) >45%, we sought to describe and analyse the potential prognostic value of echocardiographic parameters recorded not only at rest but also during a submaximal exercise stress echocardiography. Exercise-induced changes in echo parameters might improve our ability to characterize HFpEF patients. Patients were prospectively recruited in a single tertiary centre following an acute HF episode with NT-pro-BNP >300 pg/mL (BNP > 100 pg/mL) and LVEF > 45% and reassessed by exercise echo-Doppler after 4-8 weeks of dedicated treatment. Image acquisitions were standardized, and analysis made at end of follow-up blinded to patients' clinical status and outcome. In total, 60 patients having standardized echocardiographic acquisitions were included in the analysis. Twenty-six patients (43%) died or were hospitalized for HF (primary outcome). The mean ± SD workload was 45 ± 14 watts (W). Mean ± SD resting LVEF and LV global longitudinal strain was 57.6 ± 9.5% and -14.5 ± 4.2%, respectively. Mean ± SD resting E/e' was 11.3 ± 4.7 and 13.1 ± 5.3 in those patients who did not and those who did experience the primary outcome, respectively (P = 0.03). Tricuspid regurgitation (TR) peak velocity during exercise were 3.3 ± 0.5 and 3.7 ± 0.5 m/s (P = 0.01). Exercise TR was independently associated with HF-hospitalization or death after adjustment on baseline clinical and biological characteristics. Exercise echocardiography may contribute to identify HFpEF patients and especially high-risk ones. Our study suggested a prognostic value of TR recorded during an exercise. That was demonstrated independently of the value of resting E/e'. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions

  1. "Stendum, feg och impotent är Turkiets president" : En kvalitativ innehållsanalys av den tyska mediedebatten om Jan Böhmermann-affären utifrån olika argument för yttrandefrihet.

    OpenAIRE

    Lindström, Malin

    2017-01-01

    Den här uppsatsen undersöker argument för yttrandefrihet som framkommit i den så kallade Böhmermannaffären som inträffade våren 2016 i Tyskland, då den tyska satirikern Jan Böhmermann läste upp en niddikt om Turkiets president Recep Tayyip Erdoğan. Erdoğan kände sig kränkt och anmälde Böhmermann enligt ett tyskt lagrum. Undersökningen syftar till att utröna vilka typargument för yttrandefrihet som framkommit i debatten om Böhmermannaffären från olika aktörer och utifrån vilket intresse dessa ...

  2. Some selected heavy metal concentrations in water, sediment, and oysters in the Er-Ren estuary, Taiwan: chemical fractions and the implications for biomonitoring.

    Science.gov (United States)

    Chen, Yueh-Min; Li, Hong-Chun; Tsao, Tsung-Ming; Wang, Liaug-Chi; Chang, Yin

    2014-11-01

    Studies of heavy metal contamination and ecological risk in estuaries are an important emerging area of environmental science. However, there have been few detailed studies of heavy metal contamination that concern the spatial variation of heavy metal levels in water, sediment, and oyster tissue. Because of the effective uptake of heavy metals, cultured oysters are a cheap and effective subject for study. This study, conducts an experiment in the Er-Ren river to examine the biological uptake of heavy metals in farmed, cultured oysters. The distribution of copper, zinc, lead, cadmium, and arsenic concentrations in water, sediment, and oysters from the Er-Ren river is also evaluated. By sequential extraction of the sediments, the following order of mobilities is found for heavy metals Pb > Cd > As > Zn > Cu. The highest percentages of heavy metals are found in the residual phase. The mean uptake rates for young oysters are 7.24 mg kg(-1) day(-1) for Cu and 94.52 mg kg(-1) day(-1) for Zn, but that for adult oyster is 10.79 mg kg(-1) day(-1) for Cu and 137.24 mg kg(-1) day(-1) for Zn. With good policies and management, the establishment of cultured oyster frames in these contaminated tributaries and near shore environments is a potential method for removing Cu and Zn and protecting the coast.

  3. Is cardiac resynchronization therapy an option in heart failure patients with preserved ejection fraction? Justification for the ongoing KaRen project.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars; Linde, Cecilia; Daubert, Jean-Claude

    2010-01-01

    The relevance of electrical and mechanical dyssynchrony has been demonstrated in heart failure with reduced ejection fraction. Preserved ejection fraction is present in as many as 50% of patients with chronic heart failure. Recent small studies suggest that both electrical and mechanical left ventricular dyssynchrony are sometimes present in patients with heart failure and preserved ejection fraction (HFPEF). These data remain controversial and a robust validation of this hypothesis has to be achieved. In the present paper, we review in detail the concepts and try to justify the ongoing KaRen registry. This is a prospective, multicentre, international, observational study to characterize the prevalence of electrical or mechanical dyssynchrony in HFPEF and the resultant effect on prognosis. Patients are enrolled currently at the time of an acute congestive episode. The diagnosis of HFPEF is made according to clinical data, natriuretic peptides and echocardiography for the measurement of ejection fraction. Once stabilized, patients return for a hospital check-up. They undergo clinical and biological evaluation, electrocardiography and Doppler echocardiography. Thereafter, patients are followed every six months, for at least 18 months for mortality, and heart failure-related and non-cardiovascular hospitalizations. KaRen aims to characterize electrical and mechanical dyssynchrony and to assess its prognostic impact in HFPEF. The results may improve our understanding of HFPEF and generate answers to the question of whether or not dyssynchrony could be a target for cardiac resynchronization therapy in HFPEF. Copyright 2010 Elsevier Masson SAS. All rights reserved.

  4. Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.

    Directory of Open Access Journals (Sweden)

    Ali Ashek

    Full Text Available Transgenic rats with inducible expression of the mouse Ren2 gene were used to elucidate mechanisms leading to the development of hypertension and renal injury. Ren2 transgene activation was induced by administration of a naturally occurring aryl hydrocarbon, indole-3-carbinol (100 mg/kg/day by gastric gavage. Blood pressure and renal parameters were recorded in both conscious and anesthetized (butabarbital sodium; 120 mg/kg IP rats at selected time-points during the development of hypertension. Hypertension was evident by the second day of treatment, being preceded by reduced renal sodium excretion due to activation of the thiazide-sensitive sodium-chloride co-transporter. Renal injury was evident after the first day of transgene induction, being initially limited to the pre-glomerular vasculature. Mircoalbuminuria and tubuloinsterstitial injury developed once hypertension was established. Chronic treatment with either hydrochlorothiazide or an AT1 receptor antagonist normalized sodium reabsorption, significantly blunted hypertension and prevented renal injury. Urinary aldosterone excretion was increased ≈ 20 fold, but chronic mineralocorticoid receptor antagonism with spironolactone neither restored natriuretic capacity nor prevented hypertension. Spironolactone nevertheless ameliorated vascular damage and prevented albuminuria. This study finds activation of sodium-chloride co-transport to be a key mechanism in angiotensin II-dependent hypertension. Furthermore, renal vascular injury in this setting reflects both barotrauma and pressure-independent pathways associated with direct detrimental effects of angiotensin II and aldosterone.

  5. 影响公益众筹中项目筹款能力的一些相关因素--以众筹网为例%Some Related Factors Affecting the Ability to Raise Funds in the Crowdfunding of the Public Service---A Case Study of the ZhongChou Network

    Institute of Scientific and Technical Information of China (English)

    苟爱萍; 田江

    2016-01-01

    随着众筹融资和“互联网+”的发展,公益众筹开始兴起,文中通过爬虫软件获取了截至2016年6月22日众筹网所有成功结束的筹款项目的数据,通过数据分析发现了不同性质的公益项目在众筹过程中具有不同的优势,并且通过SPSS进行了数据间简单的相关性分析,发现了影响公益众筹能力的一些相关性因素和非相关因素,研究了项目信息的透明度,回报捐助的方式以及关注度对一个公益筹款项目的影响。%With the development of the Crowdfunding and“Internet plus”,the Crowdfunding of the public service begin to develop.This paper achieved all the datas of the successful public service projects in the ZhongChou network until June 22,2016 using the crawler software.Through the data analysis found that the different nature of the public service projects in the process of raising the fund has a different advantage,and through the simple correlation analysis using SPSS,found some related factors and non-related factors that affect the ability to raise fund in Crowdfunding of the public service,the influence of the transparency of project information,the way of return and the degree of concern on a public service project.

  6. New echocardiographic predictors of clinical outcome in patients presenting with heart failure and a preserved left ventricular ejection fraction: a subanalysis of the Ka (Karolinska) Ren (Rennes) Study.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars H; Oger, Emmanuel; Hage, Camilla; Persson, Hans; Reynaud, Amélie; Ennezat, Pierre-Vladimir; Bauer, Fabrice; Drouet, Elodie; Linde, Cecilia; Daubert, Claude

    2015-07-01

    To identify electrocardiographic and echocardiographic predictors of mortality and hospitalizations for heart failure (HF) in the KaRen study. KaRen is a prospective, observational study of the long-term outcomes of patients presenting with heart failure and a preserved ejection fraction (HFpEF). We identified 538 patients who presented with acute cardiac decompensation, a >100 pg/mL serum b-type natriuretic peptide (BNP) or >300 pg/mL N-terminal pro-brain natriuretic peptide (NT-proBNP) concentration and a left ventricular ejection fraction (LVEF) >45%. After 4-8 weeks of standard treatment, 413 patients (mean age = 76 ± 9 years, 55.9% women) returned for analyses of their clinical status, laboratory screen, and detailed electrocardiographic and Doppler echocardiographic recordings. They were followed for a mean of 28 months thereafter. The primary study endpoint was time to death from all causes or first hospitalization for heart failure. Mean LVEF was 62.4 ± 6.9% and median NT-proBNP 1410 pmol/L. PR interval >200 ms was present in 11.2% of patients and 14.9% had a >120 ms QRS duration, with left bundle branch block in only 6.3%. Over a mean follow-up of 28 months, 177 patients (42.9%) reached a primary study endpoint, including 61 deaths and 116 hospitalizations for heart failure. After adjustment for age, gender, New York Heart Association class, atrial fibrillation history, creatinine, sodium, BNP, ejection fraction, and right ventricular fractional shortening, only E/e' remained as a predictor, with a hazard ratio = 1.49 and P = 0.0012. The incidence of hospitalizations for HF and deaths in KaRen was high and E/e' predicted adverse clinical outcomes. These observations should help in the risk stratification and therapy of HFpEF. © 2015 The Authors. European Journal of Heart Failure © 2015 European Society of Cardiology.

  7. "en este aff ösel" in Visby : Ösel and Estland in the Gotlandic account books of Ivar Axelsson Tott 1585-87 and Sören Norby 1524-25 / Jan-Christian Schlüter

    Index Scriptorium Estoniae

    Schlüter, Jan-Christian, 1979-

    2008-01-01

    Ojamaa ja Saaremaa kontaktidest on vähe teada perioodist Saksa ordu ja Rootsi kuningate valitsemisaja vahel. Ivar Axelsson Totti ja Sören Nörby arveraamatutes mainitud kohanimede seas on Eestiga seotud nimedel küllalt suur osakaal. Ka esineb kaptenite palgaarvetel Eestist pärit isikute nimesid

  8. O Twitter de Renê Silva e a ocupação da tecnologia: o morro (do Alemão tem vez Renê Silva's Twitter and technology occupation: the time of Alemão's slum

    Directory of Open Access Journals (Sweden)

    Junot de Oliveira Maia

    2012-06-01

    Full Text Available No final do ano de 2010, durante a ocupação militar do Morro do Adeus, no Rio de Janeiro, Renê Silva, de 17 anos, destacou-se por usar o microblog Twitter para transmitir informações em tempo real sobre os acontecimentos que marcavam a invasão. O jovem, o qual fazia suas postagens de dentro da própria favela, é exemplo de sujeito pertencente a grupo periférico e que, a despeito das barreiras socioeconômicas impostas, se apropriou das TIC por meio de estratégias e táticas que, em ação, desestabilizaram a ordem hegemônica (DE CERTEAU, 1980/2008, aqui principalmente representada pelos veículos de informação em massa. Assim, este trabalho destaca como Renê, por meio de seus letramentos plurais e híbridos, se apropriou das novas tecnologias e, dessa forma, tornou-se locutor privilegiado dos conflitos que ocorriam no Complexo do Alemão.In late 2010, during the military occupation of the Adeus' slum in Rio de Janeiro, Renê Silva, 17, stood out by using the microblog Twitter to transmit real-time information about the events that marked the invasion. Silva, who made his posts from the slum itself, is an example of a subject belonging to the peripheral group and who, despite the socio-economic barriers imposed, appropriated the ICT through strategies and tactics that in action destabilized the hegemonic order (DE CERTEAU, 1980/2008, here mainly represented by the mass media. Thus, this work highlights how Silva, through his plural and hybrid literacies, appropriated new technologies and thereby became a privileged reporter of the conflicts that occurred in the Alemão's complex of slums.

  9. Observaciones sobre el debate Sahlins-Obeyesekere: la muerte del capitán Cook vista desde la antropología de René Girard

    Directory of Open Access Journals (Sweden)

    Gabriel Andrade

    2004-01-01

    Full Text Available El objetivo de este ensayo es tomar partido en la disputa entre los antropólogos Marshall Sahlins y Gananath Obeyesekere, utilizando a la obra de René Girard como instrumento teórico. De acuerdo a Sahlins, el capitán James Cook fue asesinado en Hawaii en 1779, y según testimonios posteriores, los nativos llegaron a identificar a Cook con Lono, dios de la agricultura. Obeyesekere mantiene que la versión de Sahlins es un mito colonialista de superioridad europea. La antropología de Girard nos permite comprender que, de acuerdo a la manera en que opera lo sagrado, es posible que efectivamente el capitán Cook haya sido identificado con un dios, respaldando así la posición de Sahlins.

  10. Armastuse feng shui / Peeter Rüberg

    Index Scriptorium Estoniae

    Rüberg, Peeter

    2000-01-01

    Järg Jan/13;20;27/Feb/3;10;17;23/Mar/2;9;16 ;30/Apr/13/May/4;11 lk. 22;38;56;70;87;102;118;134;150;166;198;230;278 ;296Vanal hiina kodu- ja elukunstil on igaks armuelu juhtumiks varuks praktilisi nõuandeid ja võtteid

  11. Feng shui pa-kua / Ann Tenno

    Index Scriptorium Estoniae

    Tenno, Ann, 1952-

    2003-01-01

    Pa-kua sümbol, kolmikmärkide Varane Taevane Järjestus - yin pa-kua ja Hilisem Taevane Järjestus - yang pa-kua. Inimeste kodude - majade ja aedade kujundamiseks kasutatakse Hilisema Taevase Järjestuse pa-kua'd. Pa-kua kolmikmärgid yang pa-kua järjestuses, soovitusi aia kujundamiseks. 8 ill

  12. Geomorphosite inventories for the promotion of tourism by geoheritage. The case of the Hérens and Réchy valleys (Switzerland)

    Science.gov (United States)

    Grangier, L.; Reynard, E.

    2012-04-01

    As for many Alpine valleys, the Hérens and Réchy valleys (Valais, Switzerland) have a very rich geological and geomorphological heritage, especially in terms of tectonic structure and glacial history. Despite this, very little has been done in the area to promote the geoheritage. At the moment, there is no official inventory of geoheritage in terms of Earth history or tourism promotion. This poster presents the results of a geomorphosite inventory conducted in the summer of 2011 in the Hérens and Réchy valleys. It is part of a larger project aiming at the development of geotourist products in the study area. The assessment of geomorphosites followed the method of Reynard et al. (2007), designed to evaluate both the scientific and the so-called additional values of each site, what we could consider the "intrinsic value" of the sites. 38 sites were identified and evaluated. Furthermore, this work tested the assessment of the "use value" - in terms of conservation, tourist promotion and education - of each site. A set of new assessment criteria was developed, concerning the conditions of visit (access (type, time of walking, difficulty), safety, visibility, environmental context, links with other sites), the educational value (readability, presence of educative/interpretation means), and the potential economic products. After this test, the assessment method (Reynard et al., 2007) will be improved by adding a category "use values" to the existing "scientific" and "additional values". Reference Reynard E., Fontana G., Kozlik L., Scapozza C. (2007). A method for assessing the scientific and additional values of geomorphosites, Geographica Helvetica, 62(3), 148-158.

  13. 突发群体事件后乌鲁木齐市中湾街沿街居民精神障碍流行病学调查%Epidemiological survey of mental disorder along the Zhong-wan street in the Urumqi after the emergency of group injury

    Institute of Scientific and Technical Information of China (English)

    徐向东; 吕淑云; 夏叶玲; 贾丽娜; 胡新伟; 买买提热夏提·吐尔逊; 张莉; 李月娥; 陈亮

    2014-01-01

    目的 了解乌鲁木齐市突发群体事件后中湾街沿街年龄≥15岁居民各类精神障碍的患病率、发病因素及规律,为街道社区心理卫生服务尤其是心理危机干预提供依据.方法 2009年9月5日至11月5日对乌鲁木齐市黑甲山后街社区沿街居民进行了调查,对其中中湾街沿街年龄≥15岁全体居民,由精神科医生以DSM-Ⅳ-TR轴Ⅰ障碍临床定式检查患者版进行了调查,使用DSM-Ⅳ对各类精神障碍进行诊断.结果 (1)共有931人完成了调查,精神障碍的总时点患病率为24.3%(226/931),最常见的精神障碍为创伤后应激障碍(post traumatic stress disorder,PTSD)(13.5%,126/931),重性抑郁障碍(8.7%,81/931)和未特定抑郁障碍(3.4%,32/931).(2)高暴露组总患病率为41.3%(143/346),高于低暴露组(14.2%,83/585),差异有统计学意义(P<0.01);年龄组总患病率随着年龄增大呈增高趋势(≥55岁组略有下降):15 ~ 24岁8.8%(7/192),25 ~ 34岁20.4%(44/225),35 ~44岁26.5%(77/291),45~54岁41.7%(55/132),≥55岁34.1%(31/91),差异有统计学意义(P<0.01).(3)PTSD患者自愿接受治疗23例(18.3%),2例完成治疗.结论 相关区域PTSD和重性抑郁障碍患病率位于突发群体事件后精神障碍的前两位.高暴露者精神障碍总患病率高于低暴露者,年龄<55岁人群精神障碍总患病率随年龄增大呈增高趋势.社区PTSD患者治疗依从性差.%Objective To understand the prevalence rate and factors to mental disorder in residents aged 15 years and older along the Zhong-wan street in the Urumqi after the emergency of group injury.To provide the basis for the community mental health service especially psychological crisis intervention.Methods The residents aged 15 years and older along the Zhong-wan street were assessed with the DSMⅣ-TR for making diagnosis of axis Ⅰ disorder from September 5 to November 5 in 2009.Results In the 931 residents completed the surveys

  14. Making the semiconductor-metal transition in a growth-dominant phase-change alloy InSb for double density blu-ray super-RENS-ROM disc

    Energy Technology Data Exchange (ETDEWEB)

    Hyot, Berangere [CEA, LETI, MINATEC, F- 38054 Grenoble (France)

    2012-10-15

    Phenomenologically, a semiconductor-metal transition is characterized by a sudden change in electrical properties but also in optical behaviours, as a consequence of a change in electron behaviour. The ability to induce a reversible semiconductor-metal transition in a material by varying conditions such as applied temperature or electrical field, results in attractive changes in properties that have fuelled the curiosity of scientists. In this paper, we discuss the interest of such materials exhibiting the reversible semiconductor-metal transition in the development of the next generation of optical Bly-ray discs (BD), the so-called super-resolution near field structure (super-RENS) discs and we show that InSb semiconductor material exhibits huge variations of its optical properties during the optically (thermally)-induced solid-to-liquid change corresponding to a semiconductor-metal transition. First success in the video playback on HDTV (High Definition TeleVision) display from 50 GB (BD capacity x 2) InSb-based super-RENS-ROM discs including a high definition video content with 1920 x 1080 pixels was realized in September 2009 by the super-RENS consortium joining three partners: AIST (National Institute of Advanced Industrial Science and Technology), Mitsubishi Electric Co. and LETI. Snapshot of high definition video content from InSb-based super-RENS-ROM disc corresponding to 50 GB per layer (BD capacity x 2) displayed on HDTV. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. Biometrische Untersuchungen des Stylopodiums, Zygopodiums und Metapodiums pleistozäner Ursiden im Hinblick auf die Evolution des Höhlenbären und die Klassifizierung des Fundmaterials Einhornhöhle / Harz

    OpenAIRE

    Athen, Kerstin Anja

    2007-01-01

    In der vorliegenden Dissertation "Biometrische Untersuchungen des Stylopodiums, Zygopodiums und Metapodiums pleistozäner Ursiden im Hinblick auf die Evolution des Höhlenbären und die Klassifizierung des Fundmaterials Einhornhöhle / Harz" wurden Daten des oberpliozänen Ursus etruscus, des pleistozänen Ursus deningeri sowie des Ursus spelaeus ausgewertet. Zur Datenerhebung wurden 249 Messgrößen an den Skelettelementen Humerus, Ulna, Radius, Metacarpalia I-V, Femur, Tibia, Fibula und Metatarsali...

  16. Carne y nada más: la configuración del discurso cárnico en La Carne de René de Virgilio Piñera

    Directory of Open Access Journals (Sweden)

    Sergio Antonio Mora Moreno

    2017-01-01

    Full Text Available Este artículo hace un análisis de la novela La carne de René , del escritor cubano Virgilio Piñera, desde la construcción del discurso hegemónico –al que llamo cárnico– el cual construye y define los cuerpos de los personajes y, por tanto, sus subjetividades. Así, este trabajo se pregunta por los mecanismos discursivos (como la pa- rodia y las luchas entre poder-conocimiento sobre el cuerpo que configuran el discurso cárnico y cómo este opera en los individuos de este universo literario (especialmente en René, su protagonista para que puedan entenderse como sujetos constituidos de solo carne dispuesta al dolor, sin posibilidad de hacerse una vida espiritual. René, a pesar de ejercer resistencia al discurso cárnico, sucumbe ante este, ya que no logra hacerse una individualidad que esté por fuera del discurso, por lo que no le queda más remedio que aceptar que es un ser hecho de carne y nada más.

  17. Identification and analysis of chemical constituents and rat serum metabolites in Suan-Zao-Ren granule using ultra high performance liquid chromatography quadrupole time-of-flight mass spectrometry combined with multiple data processing approaches.

    Science.gov (United States)

    Du, Yiyang; He, Bosai; Li, Qing; He, Jiao; Wang, Di; Bi, Kaishun

    2017-07-01

    Suan-Zao-Ren granule is widely used to treat insomnia in China. However, because of the complexity and diversity of the chemical compositions in traditional Chinese medicine formula, the comprehensive analysis of constituents in vitro and in vivo is rather difficult. In our study, an ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry and the PeakView® software, which uses multiple data processing approaches including product ion filter, neutral loss filter, and mass defect filter, method was developed to characterize the ingredients and rat serum metabolites in Suan-Zao-Ren granule. A total of 101 constituents were detected in vitro. Under the same analysis conditions, 68 constituents were characterized in rat serum, including 35 prototype components and 33 metabolites. The metabolic pathways of main components were also illustrated. Among them, the metabolic pathways of timosaponin AI were firstly revealed. The bioactive compounds mainly underwent the phase I metabolic pathways including hydroxylation, oxidation, hydrolysis, and phase II metabolic pathways including sulfate conjugation, glucuronide conjugation, cysteine conjugation, acetycysteine conjugation, and glutathione conjugation. In conclusion, our results showed that this analysis approach was extremely useful for the in-depth pharmacological research of Suan-Zao-Ren granule and provided a chemical basis for its rational. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Rationale and design of the Karolinska-Rennes (KaRen) prospective study of dyssynchrony in heart failure with preserved ejection fraction.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars H; Linde, Cecilia; Edner, Magnus; Lafitte, Stéphane; Persson, Hans; Bauer, Fabrice; Ohrvik, John; Ennezat, Pierre-Vladimir; Hage, Camilla; Löfman, Ida; Juilliere, Yves; Logeart, Damien; Derumeaux, Geneviève; Gueret, Pascal; Daubert, Jean-Claude

    2009-02-01

    Heart failure with preserved ejection fraction (HFPEF) is common but not well understood. Electrical dyssynchrony in systolic heart failure is harmful. Little is known about the prevalence and the prognostic impact of dyssynchrony in HFPEF. We have designed a prospective, multicenter, international, observational study to characterize HFPEF and to determine whether electrical or mechanical dyssynchrony affects prognosis. Patients presenting with acute heart failure (HF) will be screened so as to identify 400 patients with HFPEF. Inclusion criteria will be: acute presentation with Framingham criteria for HF, left ventricular ejection fraction>or=45%, brain natriuretic peptide (BNP)>100 pg/mL or NT-proBNP>300 pg/mL. Once stabilized, 4-8 weeks after the index presentation, patients will return and undergo questionnaires, serology, ECG, and Doppler echocardiography. Thereafter, patients will be followed for mortality and HF hospitalization every 6 months for at least 18 months. Sub-studies will focus on echocardiographic changes from the acute presentation to the stable condition and on exercise echocardiography, cardiopulmonary exercise testing, and serological markers. KaRen aims to characterize electrical and mechanical dyssynchrony and to assess its prognostic impact in HFPEF. The results might improve our understanding of HFPEF and generate answers to the question whether dyssynchrony could be a target for therapy in HFPEF.

  19. Students’ entrepreneurial behavior in the application of 'EkRenFaTiHa' productive entrepreneurial teaching model at culinary programs vocational schools

    Directory of Open Access Journals (Sweden)

    Badraningsih Lastariwati

    2016-06-01

    Full Text Available The purpose of the study is to observe students' entrepreneurial behaviors in the implementation of entrepreneurship processes in production subjects. The study applied production entrepreneurial teaching model to some vocational high school students with their ‘EkRenFaTiHa Catering’ as their project. The entrepreneur process was integrated in the catering production subject and it consisted of the following aspects: Exploration, business plans, facilitation, action and output. The study employed research and development approach, which referred to Plomp development model. The data were analyzed by using descriptive statistics. The research subjects were some students of 1 Sewon State Vocational High School. The results of the test on the model implementation show the students’ mastery of the entrepreneurial behaviors showing the characteristics of responsibility, innovation, honesty, independence, creativity, leadership, dilligence, discipline, cooperation, risk-taking and good communication. It also shows that there is a concrete improvement during the continuous process regarding every observed entrepreneurial behavior, and in general the students’ entrepreneurial behaviors could be classified as good.

  20. Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

    Science.gov (United States)

    Hu, Lin-lin; Zhang, Xin; Liu, Wen-juan; Li, Mei; Zhang, Yong-hua

    2015-01-01

    Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT) and Zhi Zi Chi Tang (ZZCT; SZR-ZZC) for improving sleep quality and anxiety states with four indices of Polysomnography (PSG), the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), and the Self Rating Anxiety Scale (SAS). Methods. A randomized, parallel-controlled trial compared SZR-ZZC to lorazepam tablet in insomniacs with anxiety. Patients were randomized to the SZR-ZZC treatment group (n = 60) and the lorazepam tablet treatment group (n = 59). Results. SZR-ZZC significantly improved scores on all four treatment indices. Compared with lorazepam, treatment with SZR-ZZC resulted in a significant reduction in the ISI (P = 0.029), the PSQI (P = 0.017), and wake after sleep onset (WASO; P = 0.008) scores and improved sleep architecture (P = 0.000–0.003) after a 4-week treatment period. Only one subject in the SZR-ZZC group experienced adverse side effects. Conclusion. Treatment with SZR-ZZC for 4 weeks appears to be a relatively safe and effective complementary therapeutic option when aiming to improve sleep quality and anxiety in insomniacs with anxiety. PMID:25793006

  1. Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

    Directory of Open Access Journals (Sweden)

    Lin-lin Hu

    2015-01-01

    Full Text Available Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT and Zhi Zi Chi Tang (ZZCT; SZR-ZZC for improving sleep quality and anxiety states with four indices of Polysomnography (PSG, the Insomnia Severity Index (ISI, the Pittsburgh Sleep Quality Index (PSQI, and the Self Rating Anxiety Scale (SAS. Methods. A randomized, parallel-controlled trial compared SZR-ZZC to lorazepam tablet in insomniacs with anxiety. Patients were randomized to the SZR-ZZC treatment group (n=60 and the lorazepam tablet treatment group (n=59. Results. SZR-ZZC significantly improved scores on all four treatment indices. Compared with lorazepam, treatment with SZR-ZZC resulted in a significant reduction in the ISI (P=0.029, the PSQI (P=0.017, and wake after sleep onset (WASO; P=0.008 scores and improved sleep architecture (P=0.000–0.003 after a 4-week treatment period. Only one subject in the SZR-ZZC group experienced adverse side effects. Conclusion. Treatment with SZR-ZZC for 4 weeks appears to be a relatively safe and effective complementary therapeutic option when aiming to improve sleep quality and anxiety in insomniacs with anxiety.

  2. La época presente: una aproximación a la ontología política de Søren Kierkegaard

    Directory of Open Access Journals (Sweden)

    Omar García Temprano

    2016-03-01

    Full Text Available La presente exposición se centra en el único escrito explícitamente político que salió de la pluma del pensador danés Søren Kierkegaard, en la línea de las “críticas del presente” que se popularizarían en el siglo xix. Nos referimos al opús- culo titulado La época presente, parte de una reseña literaria, donde se describe la emergente sociedad de masas, posterior a la época revolucionaria, a partir de las categorías ontológicas de la losofía que mejor re ejaba su tiempo: el hegelianismo. Las siguientes páginas se esfuerzan en mostrar que las características destacadas por Kierkegaard de la época presente, que es una época esencialmente desapasionada, se corresponden con los rasgos de la ontología re exiva que se trasluce en la dialéctica hegeliana.

  3. Caracterización de la conducta suicida en el Policlínico "René Ávila Reyes". Holguín 2007-2008

    Directory of Open Access Journals (Sweden)

    Eisy Mercedes Infantes Pérez

    2009-01-01

    Full Text Available Aborda un estudio descriptivo, de series de casos sobre el comportamiento de la conducta suicida en el Policlínico ¿René Ávila Reyes¿, Holguín .2007-2008. La muestra estuvo integrada por 52 pacientes con conducta suicida. Para la obtención de información se revisaron Historias Clínicas y discusiones de casos. En el intento suicida hubo un mayor predominio en los adolescentes, las mujeres y amas de casa. Las edades de 31 a 40 años, del sexo masculino y desocupados, se señalaron con mayor comportamiento en el suicidio. Los métodos más empleados para realizar el intento correspondieron a la ingestión de tabletas y el ahorcamiento para al suicidio. Los antecedentes patológicos familiares y personales de conducta suicida se señalaron como factor importante y el problema principal que desencadenó la conducta correspondió a la depresión marcada. Se recomendó el diseño de una estrategia de intervención comunitaria para lograr un impacto en el área de salud.

  4. Overview of renewable energies during the first six-month period of 2013. Wind energy, Photovoltaic energy, Connection schemes (S3REnR)

    International Nuclear Information System (INIS)

    2013-01-01

    Illustrated by maps, graphs and tables, the first part of this document presents and comments data related to wind energy production. It addresses the status of the wind energy production stock (connected stock in June 2013, regional distribution, distribution in terms of power range, evolution of wind turbine and wind farm power), growth perspectives, and the role of wind energy production in the supply-demand balance (production and load factor, regional distribution of production and load factor, share in consumption coverage, wind energy production flow management). Using the same kind of presentation and the same issues, the second part presents and comments data related to photovoltaic energy production in France: photovoltaic stock (connected stock in June 2013, regional distribution, distribution in terms of power range), growth perspectives, and role of photovoltaic energy production in the supply-demand balance (production and load factor, production and load factor regional distribution, role in consumption coverage). The third part briefly presents data related to Regional Schemes of Connection to the renewable energy network (S3REnR) which ensure conditions of connection to the electric grid of all renewable energies

  5. Cap a l'ordre simbòlic femení: La passió segons Renée Vivien

    Directory of Open Access Journals (Sweden)

    Lluïsa Julià

    2004-01-01

    Full Text Available This article is an interpretation of the novel which Maria-Mercè Marçal published in 1994. It highlights the main elements of the feminine symbolic space constructed out of her own sexuality and declared as different from the masculine one, taking the mythical, symbolical and real character of Renée Vivien as a starting point. Around this figment of imagination the feminine past is brought to mind and a possible future is worked out, a historical and literary universe which allows us to talk about women –with a paricular emphasis placed on the woman artist– from a complete perspective. Some referents which stand out in the novel out of her own imaginary, reproduced and created by the author, are described. In this respect, the writer's intellectual, poetic and ironical response in the cultural debate which women´s creativity continues to assume is stressed, and a few keys to the respect are given.

  6. René Andioc tenía razón: la Continuación del Semanario de Salamanca (1800

    Directory of Open Access Journals (Sweden)

    Pedro ÁLVAREZ DE MIRANDA

    2012-05-01

    Full Text Available Este trabajo está destinado a resolver uno de los «enigmas histórico- literarios» que René Andioc planteó en uno suyo de 1992. Había indicios de que el Semanario de Salamanca, publicación supuestamente concluida en 1798 (no se conocían ejemplares posteriores, había tenido una continuidad posterior, puesto que esos indicios sugerían que un artículo relacionado con Moratín se había publicado en el número del 19 de abril de 1800 de dicho periódico. Aquí se da a conocer la existencia de tres ejemplares (uno de ellos de desigual extensión frente a los otros dos de una Continuación del Semanario de Salamanca (enero a junio de 1800, en cuyo número del 19 de abril figura, en efecto, un escrito firmado por «P. OzerínJáuregui y Z.» que es una réplica al Examen en que Cristóbal Cladera había criticado la traducción del Hamlet por Moratín

  7. Pinoresinol diglucoside exhibits protective effect on dexamethasone ...

    African Journals Online (AJOL)

    Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 ... Zhan-Feng Zhang, Ji-Kang Min, Dan Wang, Jian-Ming Zhong* .... mineral density meter (Beijing Zhongxi Yuanda ..... Svedbom A, Ivergård M, Hernlund E, Rizzoli R, Kanis JA. ... Pan Y, Niu Y, Li C, Zhai Y, Zhang R, Guo X, Mei Q. Du-.

  8. The prognostic significance of atrial fibrillation in heart failure with preserved ejection function: insights from KaRen, a prospective and multicenter study.

    Science.gov (United States)

    Bosseau, Christian; Donal, Erwan; Lund, Lars H; Oger, Emmanuel; Hage, Camilla; Mulak, Geneviève; Daubert, Jean-Claude; Linde, Cecilia

    2017-06-01

    The prognostic value of atrial fibrillation (AF) in heart failure with preserved ejection fraction (HFPEF) remains controversial. We sought to study the prognostic value of AF in a prospective cohort and to characterize the HFPEF patients with AF. KaRen was a prospective, multicenter, international, observational study intended to characterize HFPEF; 538 patients presenting with an acute decompensated cardiac failure and a left ventricular EF > 45% were included. EKG and echocardiogram performed 4-8 week following the index hospitalization were analyzed in core centers. Clinical and echocardiographic characteristics of patients in sinus rhythm vs. with documented AF at enrolment (decompensated HF), upon their 4-8-week visit (in presumed stable clinical condition) and according to patients' cardiac history, were compared. The primary study endpoint was death from any cause or first hospitalization for decompensated heart failure (HF). A total of 413 patients (32% in AF) were analyzed, with a mean follow-up period of 28 months. The patients were primarily elderly individuals (mean age: 76.2 years), with a slight female predominance and a high prevalence of non-cardiovascular comorbidities. The baseline echocardiographic characteristics and the natriuretic peptide levels were indicative of a more severe heart condition among the patients with AF. However, the patients with AF exhibited a similar survival-free interval compared with the patients in sinus rhythm. In this elderly HFPEF population with a high prevalence of non-cardiovascular comorbidities, the presence of AF was not associated with a worse prognosis despite impaired clinical and echocardiographic features.ClinicalTrials.gov: NCT00774709.

  9. [Scientific revolution and embryology: rejection or transformation of antiquity? A comparison between the procreation teachings of Cesare Cremonini, William Harvey und René Descartes].

    Science.gov (United States)

    Lo Presti, Roberto

    2014-01-01

    In this paper I address the issue of the theoretical and epistemological status of embryology at the rise of the so-called "Scientific Revolution" (also in the first half of the seventeenth-century) and raise the question, in what sense and to what extent the historiographical concept of "Scientific Revolution" is applicable to the domain of embryology. To achieve this aim I compare the theories of three protagonists of the medical, scientific and philosophical debate of that age, namely Cesare Cremonini, William Harvey and René Descartes, who had very different views on the world structure and human nature and a very different concept of science, but who shared, as concerns embryological issues, an epigenetic conception of the development of the embryo. Their theories are discussed and compared in light of following questions: 1) What do Cremonini's, Harvey's and Descartes's embryological theories exactly aim to?; 2) In developing their theories, do these thinkers deal explicitly or implicitly with the Aristotelian and the Galenic embryological paradigm?; 3)Do they refer polemically to the Aristotelian and the Galenic tradition and what theoretical and/or rhetorical function have these polemical references?; 4) Do the embryological theories of Cremonini, Harvey and Descartes reflect the century-long dispute between "(Aristotelian) philosophers" and "(Galenic) doctors"?; 5) How is represented embryology as a 'scientific' and/or 'theoretical' domain? And what relationship between concepts of 'truth', 'research', 'tradition' and 'scientific progress' is implied or proposed in the embryological works of these three thinkers? What kind of use do Cremonini, Harvey and Descartes make of the argumenta ex ratione and of those ex experientia?

  10. Modificación de conocimientos sobre el autoexamen de mamas en mujeres de la Policlínica Universitaria "René Vallejo Ortiz" Changing knowledge of breast self-examination in women from "René Vallejo Ortiz" University Polyclinic

    Directory of Open Access Journals (Sweden)

    Leidys Proenza Fernández

    2012-11-01

    Full Text Available Se efectuó una intervención educativa que incluyó a 26 mujeres pertenecientes al Consultorio Médico nr 6, del área de salud de la Policlínica Universitaria "René Vallejo Ortiz" en el municipio de Manzanillo de la provincia de Granma, desde junio hasta diciembre del 2011, con vistas a modificar sus conocimientos sobre el autoexamen de mamas. Entre las variables estudiadas figuraron: edad, nivel de escolaridad, ocupación y medios de obtención de la información, por citar algunas. Para la recolección de la información se utilizaron 2 encuestas y como medida estadística la prueba de los signos. En la serie predominaron las féminas entre 20 y 39 años, con nivel de escolaridad preuniversitario y amas de casa. Los medios de obtención de la información más comunes fueron la televisión, la radio y la prensa. Se logró que la mayoría de las mujeres se realizaran el mencionado autoexamen y elevaran el nivel de conocimientos sobre el tema.An educational intervention that included 26 women belonging to the doctor's office no 6 from the health area of "René Vallejo Ortiz" University Polyclinic in Manzanillo municipality of Granma Province from June to December 2011 was carried out with the purpose of modifying their knowledge of breast self-examination. Among the variables studied were age, educational level, occupation and means of obtaining information, to mention some. For gathering information two surveys and the sign test as statistical measure were used. In the series women between 20 and 39 years prevailed, with senior high school educational level and housewives. The most common means of obtaining information were the television, radio and the press. It was achieved that most of the women undertake the aforementioned self-examination and increase their knowledge of the subject.

  11. Efficacy of MaZiRenWan, a Chinese Herbal Medicine, in Patients With Functional Constipation in a Randomized Controlled Trial.

    Science.gov (United States)

    Zhong, Linda Ld; Cheng, Chung-Wah; Kun, Wai; Dai, Liang; Hu, Dong-Dong; Ning, Zi-Wan; Xiao, Hai-Tao; Lin, Cheng-Yuan; Zhao, Ling; Huang, Tao; Tian, Ke; Chan, King-Hong; Lam, Ting-Wa; Chen, Xiao-Rui; Wong, Chi-Tak; Li, Min; Lu, Ai-Ping; Wu, Justin Cy; Bian, Zhao-Xiang

    2018-04-11

    The Chinese herbal medicine, MaZiRenWan (MZRW), has been used for more than 2000 years to treat constipation, but it has not been tested in a randomized controlled trial. We performed a trial to evaluate the efficacy and safety of MZRW, compared with the stimulant laxative senna or placebo, for patients with functional constipation (FC). We performed a double-blind, double-dummy, trial of 291 patients with FC based on Rome III criteria, seen at 8 clinics in Hong Kong from June 2013 through August 2015. Patients were observed for 2 weeks and then assigned randomly (1:1:1) to groups given MZRW (7.5 g, twice daily), senna (15 mg daily), or placebo for 8 weeks. Patients were then followed for 8 weeks and evaluated at baseline and weeks 4, 8 (end of treatment), and 16 (end of follow up). Participants recorded information on stool form and frequency, feeling of complete evacuation, and research medication taken. Data on individual bowel symptoms, global symptom improvement, and adverse events were collected. A complete response was defined as an increase ≥1 complete spontaneous bowel movement (CSBM)/week from baseline (the primary outcome). Secondary outcomes included response during the follow-up period, colonic transit, individual and global symptom assessments, quality of life measured with 36-item short form Chinese version, and adverse events. Although there was no statistically significant difference in proportions of patients with a complete response to MZRW (68%) vs. senna (57.7%) (P=.14) at week 8, there was a statistically significant difference vs. placebo (33.0%) (P<.005). At the 16-week timepoint (after the 8-week follow-up period), 47.4% of patients had a complete response to MZRW, 20.6% had a complete response to senna, and 17.5% had a complete response to placebo (P<.005 for MZRW vs. placebo). The group that received MZRW group also had significant increases in colonic transit and reduced severity of constipation, straining, incomplete evacuation, and

  12. Nudge for en Ren By

    OpenAIRE

    Thygesen, Johan; Markussen, Sofie Naver; Stage, Trine; Thomsen, Kicki; Eliassen, Mikkel; Bach, Louise

    2011-01-01

    Hvorfor træffer individer ikke altid de mest hensigtsmæssige valg? Med udgangspunkt i det udsagn har vi ved hjælp af Richard Thaler og Cass Sunsteins Nudge Improving Decisions about Health, Wealth and Happiness (2009) søgt at forklare individers kognitive biases, og hvordan handlinger udspringer af et todelt kognitivt system. Samtidig har vi med Cristina Bicchieris The Grammar of Society – The Nature and Dynamics of Social Norms (2006) en viden om sociale normers konstituerende magt på indivi...

  13. ren fra Shell

    DEFF Research Database (Denmark)

    Ørding Olsen, Anders

    2017-01-01

    Hvad kan afsløringerne om Shells mere end 25 år gamle viden om klimaforandringer lære virksomheder om disruption og strategi? Først og fremmest at undgå at se disruption som en mulig trussel, men i stedet som en fremtidig realitet og chance for vækst......Hvad kan afsløringerne om Shells mere end 25 år gamle viden om klimaforandringer lære virksomheder om disruption og strategi? Først og fremmest at undgå at se disruption som en mulig trussel, men i stedet som en fremtidig realitet og chance for vækst...

  14. [The affinity between Le family of Tong Ren Tang and acu-moxibustion as viewed from Mian xue tang zhen jiu ji cheng (Mian Xuetang's Synthetic Work of Acu-moxibustion)].

    Science.gov (United States)

    Huang, L X

    2017-11-28

    This compilation process of Mian xue tang zhen jiu ji cheng ( Mian Xuetang ' s Synthetic Work of Acu - moxibustion )was quite mysterious, the book's advent coincidentally met with several major historical events which made its value of decoding its historical functions far beyond its academic value. The editor of this book is Le Xianyang, the founder of Tong Ren Tang. While compiling this book, he also made a replica of Ming-Dynasty's Zhengtong bronze statue. More than 200 years later, Le Jingyu, the 12th generation of the Le family revised Ming Tang Tu inherited from his ancestors and engraved Ming Tang Tu on the stone for its standardization. This great achievement of Le family was no less than the recasting of the Tiansheng bronze statue and the reengraving Tong ren shu xue zhen jiu tu jing ( Illustrated Manual of Acupuncture Points of the Bronze Figure ) by support of state power for building the Beijing Imperial Hospital in the eighth year of the Zhengtong reign (1443).

  15. Impossibilidade da renúncia do uso público da razão em Hannah Arendt – “Eichmann em Jerusalém, a banalidade do mal”

    Directory of Open Access Journals (Sweden)

    Edimar Inocencio Brígido

    2017-10-01

    Full Text Available O artigo pretende revisitar a definição de uso público da razão e a impossibilidade da sua renúncia segundo Hannah Arendt com base em elementos que ela identificou na obra: “Eichmann em Jerusalém, um relato sobre a banalidade do mal”. Para tanto, apresenta uma breve evolução do conceito ético-político de razão e seu uso de Sócrates até o Iluminismo e aponta a ligação do pensamento de Arendt ao de Kant, para identificar a ampliação que ela faz da análise do uso da faculdade de julgar desenvolvida por ele. Isso porque a visão oitocentista da faculdade de julgar se mostrou insuficiente para explicar os efeitos históricos que a renúncia ao uso público da razão acarreta para a civilização a partir do fim do século XIX até os dias de hoje. Isso por força da escalada dos genocídios e massacres do período. Para isso, colheu-se dados históricos, literários e de reflexões de autores, cujo pensamento é próximo ao de Arendt e recorreu-se a outras obras da autora, tudo para ilustrar e explicar que a escalada genocida e dos massacres se dá em consonância com o crescimento das sociedades de massa industrial e pós-industrial. A conclusão a que se chega é de que a renúncia à faculdade de julgar derivada do modelo econômico e social atual e leva a uma aporia: uma contraditória ameaça à vida em nome da vida.

  16. LİSANSÜSTÜ EĞİTİM GÖREN ÖĞRENCİLERİN ÖZERK ÖĞRENME BECERİLERİNE İLİŞKİN ALGILARI

    Directory of Open Access Journals (Sweden)

    Nesrin HARK SÖYLEMEZ

    2014-12-01

    Full Text Available Bu araştırma, lisansüstü eğitim gören öğrencilerin özerk öğrenme becerilerine ilişkin algılarını belirlemek amacıyla yapılmıştır. Araştırmanın örneklemini, 2013-2014 eğitim-öğretim yılı güz döneminde lisansüstü eğitim gören 37 öğrenci oluşturmaktadır. Araştırmada nitel araştırma yönteminden yararlanılmış ve veri toplama aracı olarak açık uçlu soru formu kullanılmıştır. Araştırmadan elde edilen verilerin çözümlenmesinde betimsel analiz tekniği kullanılmıştır. Veriler, formda yer alan sorular dikkate alınarak sunulmuştur. Ayrıca lisansüstü eğitim gören öğrencilerin görüşlerini yansıtmak amacıyla doğrudan alıntılara da yer verilmiştir.  Araştırmada elde edilen bulgulara göre; lisansüstü eğitim gören öğrencilerin özerk öğrenme becerilerine sahip oldukları belirlenmiştir. Bunun yanında öğrencilerin çoğunluğu; özerk öğrenme niteliklerinden biri olan ihtiyaç duydukları kaynak ve materyallere ulaşabildiklerini, öğrenme ihtiyaçlarını dikkate alarak hedef belirlediklerini, sıklıkla not alma stratejisini kullandıklarını, uygulama yaparak kendilerini değerlendirdiklerini ifade etmişlerdir. Araştırmada ulaşılan diğer bir önemli bulgu ise, öğrencilerin büyük bir bölümünün lisansüstü eğitim sürecinde yapmış oldukları araştırmaların özerk öğrenme becerilerine önemli ölçüde katkı sağladığını düşünmeleridir.Anahtar kelimeler: Özerk öğrenme, lisansüstü eğitim, öğrenme becerileri

  17. Zona Franca de Manaus : um estudo sobre a renúncia tributária dos entes federativos e os benefícios socioeconômicos gerados pelo modelo

    OpenAIRE

    Jofre Luís da Costa Oliveira

    2011-01-01

    O presente trabalho avalia a renúncia tributária dos entes federativos e os benefícios socioeconômicos gerados pelo modelo da Zona Franca de Manaus (ZFM). Nosso objetivo foi mensurar os custos sociais do modelo por intermédio da desoneração tributária ou gastos tributários dos Entes e confrontá-los com os benefícios locais que foram medidos pelos diversos indicadores socioeconômicos. A plataforma teórica tem como sustentáculo a teoria dos pólos de Desenvolvimento e a Teoria da Base Exportador...

  18. Gravitational waves from spinning eccentric binaries

    Science.gov (United States)

    Csizmadia, Péter; Debreczeni, Gergely; Rácz, István; Vasúth, Mátyás

    2012-12-01

    This paper is to introduce a new software called CBwaves which provides a fast and accurate computational tool to determine the gravitational waveforms yielded by generic spinning binaries of neutron stars and/or black holes on eccentric orbits. This is done within the post-Newtonian (PN) framework by integrating the equations of motion and the spin precession equations, while the radiation field is determined by a simultaneous evaluation of the analytic waveforms. In applying CBwaves various physically interesting scenarios have been investigated. In particular, we have studied the appropriateness of the adiabatic approximation, and justified that the energy balance relation is indeed insensitive to the specific form of the applied radiation reaction term. By studying eccentric binary systems, it is demonstrated that circular template banks are very ineffective in identifying binaries even if they possess tiny residual orbital eccentricity, thus confirming a similar result obtained by Brown and Zimmerman (2010 Phys. Rev. D 81 024007). In addition, by investigating the validity of the energy balance relation we show that, contrary to the general expectations, the PN approximation should not be applied once the PN parameter gets beyond the critical value ˜0.08 - 0.1. Finally, by studying the early phase of the gravitational waves emitted by strongly eccentric binary systems—which could be formed e.g. in various many-body interactions in the galactic halo—we have found that they possess very specific characteristics which may be used to identify these type of binary systems. This paper is dedicated to the memory of our colleague and friend Péter Csizmadia a young physicist, computer expert and one of the best Hungarian mountaineers who disappeared in China’s Sichuan near the Ren Zhong Feng peak of the Himalayas on 23 Oct. 2009. We started to develop CBwaves jointly with Péter a couple of months before he left for China.

  19. PSİKOLOJİK RAHATLIK ALGISININ İŞGÖREN SESLİLİĞİ VE TAKIM İŞBİRLİĞİ ARASINDAKİ İLİŞKİDE ARACI DEĞİŞKEN ROLÜ

    Directory of Open Access Journals (Sweden)

    Serdar YENER

    2017-04-01

    Full Text Available Öz: Araştırmada, örgütlerde çalışanların etkinlik ve verimliliğini arttıracak düşünce ve tekliflerini sunması olarak tanımlanan işgören sesliliğinin takım işbirliğine olan etkisinde organizasyonlarda kişilerarası psikolojik risk algısı şeklinde ifade edilen psikolojik rahatlığın aracı değişken rolünün ortaya konulması amaçlanmıştır. Sinop’ta bulunan yerel bir işletmenin çalışanları (n=240 araştırmanın örneklemini oluşturmaktadır. Araştırmada verilerin analizinde SPSS 21 Paketi ve Hayes (2013’in SPSS uygulamasında aracı değişkenli modellerin ölçülmesi için geliştirmiş olduğu PROCESS 2.15 makrosu kullanılarak aracı değişkenin etkisi gözlenmiştir. Çıkan sonuçlara göre psikolojik rahatlık algısının işgören sesliliği ve takım işbirliği ilişkisinde kısmi aracılık etkisinin olduğu söylenebilir. İşgören sesliliğinin takım işbirliğine olan etkisi (β= ,28, p>.001 psikolojik rahatlık algısı ilişkiye dahil edildiğinde (β= ,25, p<.001 düşmüş fakat anlamlılığını yitirmemiştir. Abstract: The aim of this study is to analyze the mediating role of Psychological Safety which is defined as interpersonal risk perception, in the relation between employee voice which is defined as feedback and proposals to increase productivity and efficiency and team collaboration. Employees of a local business in Sinop (n=240 are composing sample. SPSS 21 and PROCESS 2.15 aplication of Hayes which is used to observe the mediating effect of variables are used to analyze the data. According to the results it can be said that there is a partial mediataing effect of psychological safety beween employee voice and team collaboration. The effect of employee voice (β=.28; p<.001, decreased after mediating variable psychological safety added to (β= -0,84 , p<.001 regression but kept it’s significance.

  20. ESTUDIO DEL EFECTO DE LA CRANEOACUPUNTURA EN PACIENTES CON ENFERMEDAD VASCULAR CEREBRAL. (EVC)

    OpenAIRE

    PEREZ BRAVO, MIGUEL

    2009-01-01

    LA ENFERMEDAD VASCULAR CEREBRAL (EVC) EN MEXICO ES UN IMPORTANTE PROBLEMA DE SALUD PUBLICA, ES LA TERCERA CAUSA DE MUERTE Y LA SEGUNDA EN PRODUCIR INCAPACIDAD NEUROLOGICA. EL OBJETIVO DE ESTE ESTUDIO FUE EVALUAR EL EFECTO DE LA CRANEOACUPUNTURA EN PACIENTES CON ENFERMEDAD VASCULAR CEREBRAL (ZHONG FENG). EL PRESENTE ES UN ESTUDIO EXPERIMENTAL, PROSPECTIVO Y LONGITUDINAL, REALIZADO EN EL HOSPITAL DEL ISSSTE DE LA CIUDAD DE PUEBLA, A UN GRUPO DE 11 PACIENTES DE AMBOS SEXOS, CON...

  1. Toxicity evaluation of biodegradable chitosan nanoparticles using a zebrafish embryo model

    OpenAIRE

    Hu YL; Qi W; Han F; Shao JZ; Gao JQ

    2011-01-01

    Yu-Lan Hu1, Wang Qi1, Feng Han2, Jian-Zhong Shao3, Jian-Qing Gao11Institute of Pharmaceutics, College of Pharmaceutical Sciences, 2Institute of Pharmacology, Toxicology and Biochemical Pharmaceutics, 3College of Life Sciences, Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaBackground: Although there are a number of reports regarding the toxicity evaluation of inorganic nanoparticles, knowledge on bi...

  2. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 85-91 Research Article. Cloning and study of adult-tissue-specific expression of Sox9 in Cyprinus carpio · Du Qi-Yan Wang Feng-Yu Hua Hui-Ying Chang Zhong-Jie · More Details Abstract Fulltext PDF. The Sox9 gene is one of the important transcription factors in the development of many tissues and organs, particularly ...

  3. Under the Jade Vault Lei Feng Salutes Mark Twain.

    Science.gov (United States)

    Krysl, Marilyn

    1984-01-01

    The experiences of a teacher who lectured undergraduates in the People's Republic of China on the American short story and taught a refresher course for Chinese teachers of English at the Tianjin Foreign Language Institute are presented. (Author/MLW)

  4. Seeking Feng Shui in US-China Rhetoric - Words Matter

    Science.gov (United States)

    2017-03-31

    opening with the International Monetary Fund, Ebola assistance, peacekeeping operations, and infrastructure development while also acknowledging that...send a frigate to Libya to evacuate thousands of Chinese nationals and subsequently to Yemen .17 Militarily, China appears to consistently

  5. Lider-Üye Etkileşiminin İşgören Performansına Etkisinde Çalışanların Örgütsel Adalet Algılarının Rolü

    Directory of Open Access Journals (Sweden)

    Hakan TURGUT

    2015-09-01

    Full Text Available Bu çalışmanın amacı, lider-üye etkileşiminin çalışanların örgütsel adalet algıları ile performansları üzerindeki etkilerini belirlemek ve örgütsel adaletin, lider-üye etkileşimi ile işgören performansı arasındaki ilişkide aracılık rolünün bulunup bulunmadığını araştırmaktır. Bu amaçla Çorum’da bulunan orta öğretim seviyesindeki 20 farklı okulda görevli 471 öğretmenin katılımı ile bir çalışma yapılmıştır. Araştırma sonucunda; lider üye etkileşiminin, örgütsel adalet boyutlarını (dağıtım, işlemsel, kişilerarası, bilgisel ve işgören performansını, işlemsel, kişilerarası ve bilgisel adaletin de işgören performansını anlamlı ve pozitif yönde etkilediği görülmüş, ayrıca işlemsel, kişilerarası ve bilgisel adaletin lider üye etkileşimi ile işgören performansı ilişkisinde tam aracılık rollerinin bulunduğu belirlenmiştir.

  6. Caracterización de la violencia intrafamiliar hacia la mujer. Consultorio No 1. Policlínico "René Ávila Reyes. Holguín. 2008

    Directory of Open Access Journals (Sweden)

    Eisy Mercedes Infantes Pérez

    2009-01-01

    Full Text Available Aborda un estudio descriptivo y transversal sobre el comportamiento de la violencia intrafamiliar hacia la mujer, en el consultorio 1 del Policlínico "René Ávila Reyes", en Holguín en el año 2008. La muestra quedó conformada por 101 mujeres, que luego de aplicarle una entrevista refirieron haber sido sometida a algún acto de violencia por parte de su pareja. Existió un mayor comportamiento de la violencia intrafamiliar en mujeres en edades comprendidas de 25 a 44 años, con escolaridad de preuniversitario o técnico medio y en las trabajadoras. El tipo de violencia que predominó correspondió al psicológico y con un tiempo de relación de pareja 6 a 10 años. Los factores que incidieron en la aparición del maltrato estuvieron dados por la mala comunicación en el hogar y la ingestión de bebidas alcohólicas. Se recomendó la realización de una intervención educativa comunitaria para lograr la reducción de esta problemática.

  7. Développement de l’agriculture en montagne et rôle des rapports de proximité :le cas du Val d’Hérens (Valais, Suisse

    Directory of Open Access Journals (Sweden)

    Valérie Miéville-Ott

    2010-11-01

    Full Text Available L’article examine la dynamique de développement agricole d’une petite région de montagne, le Val d’Hérens (Valais, Suisse. Celle-ci connaît une diminution des surfaces et des exploitations agricoles mais aussi de l’activité des laiteries. Ce dernier phénomène pose question car il ne proviendrait pas de la baisse de demande du marché mais d’un manque de production laitière. Pour y répondre, on propose alors d’analyser l’évolution des rapports entre les éleveurs et leurs organisations en utilisant les concepts de l’économie de proximités et notamment la distinction entre proximité relationnelle et proximité organisationnelle.The article examines the agricultural dynamics of a small mountain region, the Val d’Herens (Valais, Suisse. This region faces a decrease of its agricultural area and of its number of farms but also of the activity of the dairies. This last phenomenon raises a question because it would not come from the fall of market demand but a lack of milk production. To answer this question, we propose to analyse the evolution of the relationships between the farmers and the local organizations by using the concepts of the economics of proximity, in particular the distinction between relational proximity and organizational proximity.

  8. René Girard a jeho mimetická teorie společnosti jako možné východisko k nové sociologické teorii

    Directory of Open Access Journals (Sweden)

    Marián Kišš

    2017-10-01

    Full Text Available The presented article introduces René Girard’s thought, especially the main components of his mimetic theory of culture. The author identifies in Girard’s work two main lines of thought: firstly, the part which covers the psychosocial effects of mimetism on the micro-social level; secondly, the part which deals with the effects of mimetism on the macro-social level and with the impact it has on the genesis and preservation of social structure. The author further explicates Girard’s understanding of ritual, myth, the sacred victim, the sacred monarchy and the relation between religion and society in general. The final part of the article considers the potential inspiration and relevance of Girard’s work for sociological theory. The author argues that the primary task is now to examine the relation of Girard’s thought to Durkheim’s theory of society. He further suggests to take a new look (with the help of Girard’s work at the old theoretical dispute between Émile Durkheim and Gabriel Tarde, and examine, to bridge the differences between Durkheim and Tarde. The author considers such step especially relevant since Girard’s thought is grounded in the Durkheimian tradition and – at the same time – Girard’s key concept of mimesis plays central role in Tarde’s sociology. This is the direction towards which the author intends to work further in his own research.

  9. González de la Vega, René. (2017. Tolerance and Modern Liberalism. From Paradox to Aretaic Moral Ideal. Maryland, United States of America: Lexington. 231 pp.

    Directory of Open Access Journals (Sweden)

    Guillermo Lariguet

    2017-06-01

    Full Text Available In political and moral philosophy we are used to an uninterrupted succession of texts, heirs of the liberal traditions (headed by John Rawls, communitarians (led by the likes of Michael Sandel, Charles Taylor, etc., analytical Marxists (authors like Gerald Cohen, Jon Elster, etc..Besides the names mentioned above, there is a succession of texts that tend to give rise to a sense of routine and, as a result, of lethargy. It is the feeling that political and moral philosophy has reached a plateau within a set of accepted doctrines. Doctrines which, to paraphrase Thomas Kuhn, make up a kind of “normal science” of philosophical theory.But from time to time, the routine drowsiness is sharply interrupted. This happens when works of philosophy show up to question prevailing theories in political philosophy. Such is the case of the work I propose to review herein. It is the work of Mexican philosopher René González de la Vega, whose text on political philosophy features philosophical rigour, originality and depth...

  10. Strukturell-organisatorische Entwicklung und Etablierung eines interdisziplinären Trainingszentrums für klinisch-praktische Fertigkeiten [Structural and organizational development and establishment of an interdisciplinary Skills Lab

    Directory of Open Access Journals (Sweden)

    Dott, Wolfgang

    2010-02-01

    rztliche Handeln essentiell sind. Im Juli 2005 begann der Aufbau eines interdisziplinären Trainingszentrums an der medizinischen Fakultät der Rheinisch-Westfälischen Technischen Hochschule Aachen, genannt „AIXTRA“ (Aachener interdisziplinäres Trainingszentrum für medizinische Ausbildung. Sach- und Personalmittel zur strukturellen und methodischen Etablierung des sog. Skillslab wurden zunächst aus einem fakultätsinternen Förderprogramm für innovative Lehrkonzepte, im weiteren Verlauf zum überwiegenden Teil aus Studienbeiträgen zur Verfügung gestellt. Methodik: Im Vorfeld wurden die folgenden notwendigen Schritte eines Projektmanagements erarbeitet: Entwicklung eines methodischen Rahmenkonzeptes, Definition der inhaltlichen Ausrichtung und Auswahl der Fertigkeiten, Schaffung infrastruktureller Voraussetzungen (Räume, Unterrichtsmaterial, Personal, Konzeptionierung von „Pilot-Kursen“, Realisierung repräsentabler „Meilensteine“, Gewinnung weiterer potenter fakultätsinterner Partner für zukünftigen Ausbau, Implementierung Kursangebot in laufende Curricula, Evaluation der Einzel-Kurse und des Gesamtkonzeptes. Ergebnis: Die vorab festgelegten Teilschritte des Projektmanagements erwiesen sich als zielführend bei der Umsetzung des Projektes. Eine „Minimal“-Infrastruktur in Bezug auf räumliche und personelle Ressourcen wurde etabliert, das methodische Konzept umgesetzt. Im Sommersemester 2008 besuchten insgesamt 709 Teilnehmer in 133 fakultativen Kursen und ca. 900 Studierende in curricularen Veranstaltungen das Skillslab „AIXTRA“. Schlussfolgerung: Nach drei Jahren wird im interdisziplinären Trainingszentrum eine breite Palette von Kursen angeboten, in denen Studierende praktische Fertigkeiten erlernen, trainieren und optimieren können. Die bisher gewonnenen Erfahrungen in der Konzeptionierung und Organisation des Kursprogramms sind essentielle Grundlage für den weiteren strukturellen und methodisch-didaktischen Ausbau des Skillslab.

  11. İŞGÖREN SEÇİM SÜRECİNDEKİ KRİTİK FAALİYETLERİN ANALİTİK HİYERARŞİ SÜRECİ İLE DEĞERLENDİRİLMESİ

    Directory of Open Access Journals (Sweden)

    Nurcan TEMİZ

    2015-10-01

    Full Text Available ÖZ: Proje, zaman, kaynak ve para gibi kısıtları olan, belirli bir amacı başarmak için başlangıç ve bitiş sürelerine sahip ve öncelik ilişkileri olan bir takım faaliyetlerden oluşan bir süreçtir. İşgören seçimi her işletme için hayati bir öneme sahiptir. Bu süreç, işletmenin ihtiyaçlarına uygun işgücünü bulma ve işletmeye dahil etme faaliyetlerinden oluşan bir proje gibi düşünülebilir. Bu çalışmada bir fast food işletmesinin müdür adayı işe alım süreci incelenmiştir. İşgören seçim sürecinde işletme tarafından uygulanan faaliyetlerin öncelik ilişkileri kullanılarak proje planlama tekniklerinden Kritik Yol Yöntemi (CPM ile projenin şebekesi çizilmiş, tüm faaliyetler için en erken başlama, en erken bitiş, en geç başlama, en geç bitiş süreleri, toplam boşluklar ve serbest boşluklar hesaplanmış, kritik faaliyetler bulunmuştur. Daha sonra kritik faaliyetlerden bazılarının önceliklerini (göreli önemlerini bulmak için Analitik Hiyerarşi Süreci (AHS kullanılmıştır. ABSTRACT: Project is a process, which has restrictions such as time, resource and money, consisting of a set of activities that have starting and finishing time and precedency relations in order to achieve a specific purpose. Personnel selection has a vital importance for every business. This process can be considered as a project that consists of activities such as finding correct labour force and incorporating them to the organization. In this study personnel selection process of fast food organization was examined. By using precedence relationships of activities, pursued by organization in the personnel selection process, network of project is drawn via Critical Path Method (CPM, which is one of the project planning techniques, earliest start and earliest finish times, latest start and latest finish times, total and free float of all activities were calculated and critical activities were found. Then

  12. Predominance of AT1 Blockade Over Mas–Mediated Angiotensin-(1–7) Mechanisms in the Regulation of Blood Pressure and Renin–Angiotensin System in mRen2.Lewis Rats

    Science.gov (United States)

    2013-01-01

    BACKGROUND We investigated whether the antihypertensive actions of the angiotensin II (Ang II) receptor (AT1-R) blocker, olmesartan medoxomil, may in part be mediated by increased Ang-(1–7) in the absence of significant changes in plasma Ang II. METHODS mRen2.Lewis congenic hypertensive rats were administered either a vehicle (n = 14) or olmesartan (0.5mg/kg/day; n = 14) by osmotic minipumps. Two weeks later, rats from both groups were further randomized to receive either the mas receptor antagonist A-779 (0.5mg/kg/day; n = 7 per group) or its vehicle (n = 7 per group) for the next 4 weeks. Blood pressure was monitored by telemetry, and circulating and tissue components of the renin–angiotensin system (RAS) were measured at the completion of the experiments. RESULTS Antihypertensive effects of olmesartan were associated with an increase in plasma renin concentration, plasma Ang I, Ang II, and Ang-(1–7), whereas serum aldosterone levels and kidney Ang II content were reduced. Preserved Ang-(1–7) content in kidneys was associated with increases of ACE2 protein but not activity and no changes on serum and kidney ACE activity. There was no change in cardiac peptide levels after olmesartan treatment. The antihypertensive effects of olmesartan were not altered by concomitant administration of the Ang-(1–7) receptor antagonist except for a mild further increase in plasma renin concentration. CONCLUSIONS Our study highlights the independent regulation of RAS among plasma, heart, and kidney tissue in response to AT1-R blockade. Ang-(1–7) through the mas receptor does not mediate long-term effects of olmesartan besides counterbalancing renin release in response to AT1-R blockade. PMID:23459599

  13. 王友仁点穴开合按动法针对踝关节扭伤推拿经验浅析%Discussion on WANG You-ren's Treatment for Sprain of Ankle with Andong Therapy of Pressing Acupoint Combined with Joint Switching

    Institute of Scientific and Technical Information of China (English)

    包庆旭

    2017-01-01

    This article focused on WANG You-ren chief physician's Andong therapy theory system, systematically summarized the treatment ideas and characteristics of acute phase for the sprain of ankle. Combined with typical cases, details of WANG You-ren chief physician's treatment with specific press method, remote press method, holographic press method, and corresponding to the press method for the acupoints principle were introduced. WANG You-ren chief physician also proposed early treatment and active protection when people have sprain of ankle, with a purpose to achieve the good efficacy, such as relieve acute pain, reduce swelling, and few sequelae.%本文重点对王友仁主任医师以按动疗法理论体系为纲要,对踝关节扭伤急性期的治疗思路和特色手法进行系统总结,并结合典型病例,详细介绍王友仁主任医师用特定按动法、远端按动法、全息按动法、对应按动法为取穴原则,以达到点穴镇痛在先、开合按动顺筋归位在后的推拿治疗方法.王友仁主任医师提出踝关节扭伤后应及早治疗、积极防护,达到急者镇痛、消肿,缓者后遗症少的理念,在临床上获得满意疗效.

  14. Novel circulatory connection from the acupoint Zhong Wan(CV12 to pancreas

    Directory of Open Access Journals (Sweden)

    Minsoo Kim

    2008-03-01

    Full Text Available Objectives : Demonstrating a novel circulatory path from the acupoint(CV12 to the pancreas. Method : Alcian blue(1% solution, 20μl, pH 7.4 was injected into the acupoint(CV12. Two hours later the surfaces of internal organs were observed by using a stereomicroscope. Results : Alcian blue arrived and colored the omental fat band(OFB on the pancreas. The OFB connected the head and tail of the pancreas, the pancreas and the spleen, and the pancreas and the stomach. Conclusion : The existence of a novel circulatory path from the acupoint CV12 to the pancreas and its OFB was demonstrated.

  15. New Perspectives on Chinese Herbal Medicine (Zhong-Yao) Research and Development

    Science.gov (United States)

    Pan, Si-Yuan; Chen, Si-Bao; Dong, Hong-Guang; Yu, Zhi-Ling; Dong, Ji-Cui; Long, Zhi-Xian; Fong, Wang-Fun; Han, Yi-Fan; Ko, Kam-Ming

    2011-01-01

    Synthetic chemical drugs, while being efficacious in the clinical management of many diseases, are often associated with undesirable side effects in patients. It is now clear that the need of therapeutic intervention in many clinical conditions cannot be satisfactorily met by synthetic chemical drugs. Since the research and development of new chemical drugs remain time-consuming, capital-intensive and risky, much effort has been put in the search for alternative routes for drug discovery in China. This narrative review illustrates various approaches to the research and drug discovery in Chinese herbal medicine. Although this article focuses on Chinese traditional drugs, it is also conducive to the development of other traditional remedies and innovative drug discovery. PMID:21785622

  16. New Perspectives on Chinese Herbal Medicine (Zhong-Yao Research and Development

    Directory of Open Access Journals (Sweden)

    Si-Yuan Pan

    2011-01-01

    Full Text Available Synthetic chemical drugs, while being efficacious in the clinical management of many diseases, are often associated with undesirable side effects in patients. It is now clear that the need of therapeutic intervention in many clinical conditions cannot be satisfactorily met by synthetic chemical drugs. Since the research and development of new chemical drugs remain time-consuming, capital-intensive and risky, much effort has been put in the search for alternative routes for drug discovery in China. This narrative review illustrates various approaches to the research and drug discovery in Chinese herbal medicine. Although this article focuses on Chinese traditional drugs, it is also conducive to the development of other traditional remedies and innovative drug discovery.

  17. Lettres inédites a René Demeurisse (1895-1961, placeur au salon de la société nationale des beaux-arts en 1921

    Directory of Open Access Journals (Sweden)

    Claire Maingon

    2007-01-01

    Full Text Available René Demeurisse (1895-1962 fut un fidèle exposant des Salons parisiens, ces fiefs de l’art vivant où se jouaient la carrière des artistes depuis le XVIIe siècle. Ce peintre figuratif de la génération du feu, élève d’Albert Besnard et ami du sculpteur animalier François Pompon, était membre associé de la Société Nationale des Beaux-Arts créée en 1890. Les plus grands noms de l’Ecole française, dont Auguste Rodin et Antoine Bourdelle, y participèrent avant la création du Salon d’Automne. En 1921, Demeurisse fut chargé avec Henri le Sidaner du placement d’un millier de toiles au Salon de la Nationale des Beaux-Arts. Cette tâche passionnante et ingrate était un exercice périlleux. Tous les artistes du Salon souhaitaient être exposés le plus visiblement possible, dans la salle bénéficiant des plus beaux éclairages et de la meilleure fréquentation afin de vendre leur œuvre et d’être cités dans la presse. Il y aurait les élus et les autres, ceux dont les envois plus médiocres finiraient dans les recoins obscurs du Grand Palais. Les archives du peintre conservent notamment trois lettres remarquables d’exposants exprimant leurs désirs d’accrochage qui apportent un éclairage nouveau sur la question du rôle des placeurs. Ces documents totalement inédits révèlent une facette méconnue de l’organisation du Salon et du tempérament d’un artiste dont le principal mérite était la sincérité.

  18. Jeget i svingdøren

    DEFF Research Database (Denmark)

    Ørjasæter, Kristin

    2006-01-01

    , både selvbiografisk fiktivt  og selvbiografisk dokumenteret. De to læsemåder lader sig vanskeligt forene medmindre læseren er villig til at forholde sig til to verdener samtidigt, én virkelig, hvor skriften kommer fra og én fiktiv, som den også refererer til. I artiklen præsenterer jeg Genette og de...

  19. ren Kierkegaard og filosofisk terapi

    DEFF Research Database (Denmark)

    Dræby, Anders

    Præsentationen tager afsæt i muligheden for at forstå Kierkegaards forfatterskab som en nær efterkommer af den antikke udlægning af filosofien som en terapeutisk livspraksis. Det sker med spørgen til: (1) hvori det terapeutiske moment i forfatterskabet består; og (2) hvorledes det kan bringes i a...

  20. Sat uden for døren?

    DEFF Research Database (Denmark)

    Ryom, Knud Eske

    2014-01-01

    KOMMENTAR. Kan gruppecoaching af udsatte drenge på Nørrebro fungere som en redningsplanke til en ’fortabt’ gruppe? Ph.d.-studerende Knud Ryom fortæller her om, hvad gruppecoaching kan, og hvorfor han tilbyder det til udsatte unge i sit forskningsprojekt....

  1. Ingeniørens metode som undervisningspraksis

    DEFF Research Database (Denmark)

    Sillasen, Martin Krabbe

    2015-01-01

    På BIG BANG-konferencen 2015 kunne man opleve ingeniør og underviser Ann Kaiser fortælle om ingeniørers arbejdsmetode, og hvordan hun har brugt det til at skabe en motiverende og illustrativ naturvidenskabelig undervisning. Arbejdsmetoden kaldes for Engineering Design Process (EDP)....

  2. The geometry of René Descartes

    CERN Document Server

    Descartes, René

    1954-01-01

    The great work that founded analytical geometry. Includes the original French text, Descartes' own diagrams, and the definitive Smith-Latham translation. "The greatest single step ever made in the progress of the exact sciences." - John Stuart Mill.

  3. ren Kierkegaard og blikkets koder

    DEFF Research Database (Denmark)

    Linnet, Ragni

    out of the original context, emptying them of any, also transcendent, content, and filling them with new significance. Here the thesis shows how Kierkegaard applies an allegorical approach to his antetypes and concludes that these antetypes interact with the indirect notification form, and can......, the thesis concludes that the mediating, reconciling figure in Hegel is inflated, with special emphasis on the classicising features in Hegel, while the romantic, form reflexive aspects of his aesthetic are abjected. This entails, for example, that Hegel's descriptions of the dialectic of colour and of its......'s aesthetic loses a significant proportion of its resilience and explosiveness. Finally, in view of the thesis' interest in the ambiguity of Heiberg's relation to the painting, I can show how there is a hitherto unobserved link between the Golden Age painting and the Italian (Venetian) baroque and proto...

  4. 資訊素養與商業教育結合之理念與實施──以逢甲大學Sunny Net商學專業網站為例 | A Practical Application of Information Literacy in Business Education── Using a Web Site to Teach Lifelong Learning in Feng Chia University

    Directory of Open Access Journals (Sweden)

    景祥祜、張簡誌誠 Hsiang-Hoo S. Ching、J. J. Chang-Chien

    1999-10-01

    Full Text Available

    頁次:63-70

    資訊素養融入專業課程的教學理念已愈來愈受到重視,但國內商業教育卻鮮少有此一理念。本文首先探討現階段大學商業教育教學的概況,以反映資訊素養教育的重要性及迫切性。其次,討論大學體制內於商業教育課程中實施資訊素養教育的限制因素,進一步討論如何誘導資訊素養結合商業教育理念,階段性策略的構思,接著說明理念實踐的過程,並介紹逢甲大學商學專業網Sunny Net的現況,分享初步的成果,且提出未來展望,以尋求建立一個可以適用在我國商學專業學科的教學模式。

    Although efforts to integrate information literacy throughout educational curriculums is growing, it has not received much attention in Taiwan's business education at the post-secondary level. The purpose of this study is to explain the developing role of information literacy in business education and to analyze the present institutional constraints in its implementation. This study presents a pioneering project, Sunny Net sponsored by Feng Chia University, which is a resource-based learning environment requiring web site maintenance in order to promote student initiative and to help students recognize when there is a need for information, to identify the information for that need, and to be able to locate, to evaluate

  5. Wahlfach Teamarbeit: Ergebnisse eines Pilotprojektes zur interprofessionellen und interdisziplinären Ausbildung mit formativem Team-OSCE (TOSCE [Teamwork elective: Results of a German pilot project on interprofessional and interdisciplinary education with formative team OSCE

    Directory of Open Access Journals (Sweden)

    Schmidt, Anita

    2010-08-01

    Full Text Available [english] Aims: There is a growing need to implement teamworking in medical education. In reality, interdisciplinary and interprofessional education is often absent. Here we describe a pilot trial developed jointly by the nursing college and the medical faculty in Erlangen (Germany in which nursing students and undergraduate medical students formed interprofessional teams and were confronted with interprofessional cases using simulated patients (SPs and phantoms. The elective was planned using standard curriculum planning instruments and finally evaluated with a novel formative team OSCE (Objective Structured Clinical Evaluation instrument.Methods: During one year, 20 nursing students participated voluntarily in the project and 10 medical students took the course as an elective. Results: The pilot project was first performed with two tutors, one from the medical school and one from the nursing school, as well as one to two SPs. During the second course, there was only one tutor. Overall evaluation of the voluntary students was good, with some elements (acute stroke, factual knowledge, and general organizational problems that needed to be improved. Performance of a four-station team OSCE was feasible, but raters reported problems in assessing individuals and the team at the same time. Interobserver agreement was satisfactory (kappa 0.35.Conclusions: Interdisciplinary and interprofessional education between a nursing school and a medical school is feasible within an elective, but requires substantial personnel resources. Design and performance of a team OSCE is possible. The validity of the test has to be shown on follow-up.[german] Zielsetzung: Das Lernziel „Fähigkeit zur interprofessionellen und interdisziplinären Teamarbeit“ wird sowohl in der aktuellen Approbationsordnung für Ärzte als auch im Krankenpflegegesetz gefordert. In der Realität gibt es in beiden Ausbildungen kaum gemeinsame Lehreinheiten. Wir beschreiben ein Pilotprojekt

  6. Renewables 2018 - Global status report. A comprehensive annual overview of the state of renewable energy. Advancing the global renewable energy transition - Highlights of the REN21 Renewables 2018 Global Status Report in perspective

    International Nuclear Information System (INIS)

    Sawin, Janet L.; Sverrisson, Freyr; Rutovitz, Jay; Dwyer, Scott; Teske, Sven; Murdock, Hannah E.; Adib, Rana; Guerra, Flavia; Murdock, Hannah E.; Blanning, Linh H.; Guerra, Flavia; Hamirwasia, Vibhushree; Misra, Archita; Satzinger, Katharina; Williamson, Laura E.; Lie, Mimi; Nilsson, Anna; Aberg, Emma; Weckend, Stephanie; Wuester, Henning; Ferroukhi, Rabia; Garcia, Celia; Khalid, Arslan; Renner, Michael; Taylor, Michael; Epp, Barbel; Seyboth, Kristin; Skeen, Jonathan; Kamiya, George; Munuera, Luis; Appavou, Fabiani; Brown, Adam; Kondev, Bozhil; Musolino, Evan; Brown, Adam; Mastny, Lisa; Arris, Lelani

    2018-06-01

    REN21's Renewables 2018 Global Status Report presents developments and trends through the end of 2017, as well as observed trends from early 2018 where available. Renewable power accounted for 70% of net additions to global power generating capacity in 2017, the largest increase in renewable power capacity in modern history, according to REN21's Renewables 2018 Global Status Report (GSR). But the heating, cooling and transport sectors - which together account for about four-fifths of global final energy demand - continue to lag far behind the power sector. The GSR, published today, is the most comprehensive annual overview of the state of renewable energy worldwide. New solar photovoltaic (PV) capacity reached record levels: Solar PV additions were up 29% relative to 2016, to 98 GW. More solar PV generating capacity was added to the electricity system than net capacity additions of coal, natural gas and nuclear power combined. Wind power also drove the uptake of renewables with 52 GW added globally. Investment in new renewable power capacity was more than twice that of net, new fossil fuel and nuclear power capacity combined, despite large, ongoing subsidies for fossil fuel generation. More than two-thirds of investments in power generation were in renewables in 2017, thanks to their increasing cost-competitiveness - and the share of renewables in the power sector is expected to only continue to rise. Investment in renewables was regionally concentrated: China, Europe and the United States accounted for nearly 75% of global investment in renewables in 2017. However, when measured per unit of gross domestic product (GDP), the Marshall Islands, Rwanda, the Solomon Islands, Guinea Bissau, and many other developing countries are investing as much as or more in renewables than developed and emerging economies. Both energy demand and energy-related CO 2 emissions rose substantially for the first time in four years. Energy-related CO 2 emissions rose by 1

  7. Is tamoxifen associated with an increased risk for thromboembolic complications in patients undergoing microvascular breast reconstruction? [Ist die Einnahme von Tamoxifen zum Zeitpunkt der mikrovaskulären Brustrekonstruktion mit einer erhöhten Rate an thrombembolischen Komplikationen assoziiert?

    Directory of Open Access Journals (Sweden)

    Krämer, Robert

    2013-02-01

    des hormonrezeptorpen Brustkrebses postmenopausaler Frauen abgelöst. Tamoxifen ist mit einem ca. zweifach erhöhten Risiko für thrombembolische Komplikationen (tiefe Beinvenenthrombose, Lungenembolie assoziiert. Vor dem Hintergrund einer aktuellen und im Februar 2012 im Journal of Plastic and Reconstructive Surgery erschienenen retrospektiven Studie mit Nachweis einer erhöhten Komplikationsrate freier Lappentransplantate zur Brustrekonstruktion unter Tamoxifen-Einnahme haben wir unser Patientenkollektiv nach mikrochirurgischer Brustrekonstruktion retrospektiv auf Minor- und Major-Komplikationen einschließlich thrombembolischer Ereignisse insbesondere vor dem Hintergrund einer perioperativen Tamoxifeneinnahme untersucht. Eingeschlossen wurden insgesamt 29 Patientinnen nach mikrochirurgischer autologer Brustrekonstruktion. Es wurden mikrovaskuläre Lappenkomplikationen und Lappenverluste von Patientinnen ohne und mit Einnahme von Tamoxifen und Aromatasehemmern zum Zeitpunkt der mikrochirurgischen Brustrekonstruktion verglichen. 25 Patientinnen (86,2% erhielten eine DIEP-Lappenplastik und 4 (13,8% eine TRAM-Lappenplastik. Fernerhin verglichen wir die Rate allgemeiner thrombembolischer Ereignisse unter Berücksichtigung sonstiger Nebendiagnosen und Risikofaktoren. Von insgesamt 29 Patientinnen standen zum Zeitpunkt der mikrovaskulären Brustrekonstruktion 3 unter einer Aromatasehemmer-Therapie und 5 unter einer Tamoxifen-Therapie. Insgesamt traten in 11 Fällen (37,9% postoperative Komplikationen auf, in 5 Fällen handelte es sich hierbei um Major-Komplikationen (mit einem Lappenverlust und in um Minorkomplikationen. Unter Tamoxifeneinnahme kam es in einem Fall zu einer Minorkomplikation, und in einem anderen Fall zu einem thrombembolisch bedingten Lappenverlust. Insgesamt kam es postoperativ zu einem thrombembolischen Ereignis in Form einer Lungenembolie ohne Assoziation zur Tamoxifen-Therapie.Die Anzahl thrombembolischer Ereignisse stellten sich mit und ohne

  8. Sakarya Özel Eğitim Kurumunda Eğitim Gören Çocukların Beslenme Tarzında Ebeveynlerin Bilgi ve Tutumlarının İncelenmesi

    Directory of Open Access Journals (Sweden)

    Süleyman KALELİ

    2017-06-01

    Full Text Available Beslenme büyüme ve gelişimin sağlanması, sağlıklı bir yaşam ve sağlıklı bir gelecek için çocukluk evresinde çok önemlidir. Otizm ve down sendromu bir takım benzerlikleri ve farklılıkları gösteren genetik hastalıklar arasında yer almaktadır. Down sendromlu veya otistik çocuklar beslenme açısından riskli bir gruptur. Bu araştırma Sakarya Özel Eğitim Kurumunda eğitim gören çocukların beslenme tarzları ve ebeveynlerin çocuk beslenmesine yönelik tutumlarının incelenmesi amacıyla planlanmıştır. 30 Gönüllü öğrenci velilerine demografik bilgiler haricinde evet/hayır içeren 17 (S1, S2,…,S17 soru sorulmuştur. Ayrıca okul çağında sıkça kullanılan 22 adet gıda maddesi tablosundaki yiyeceklerin sıklığı sorgulanmıştır. S4 (%45,2 evet ve %54,8 hayır, S8 (%41,9 evet ve %54,8 hayır, S15 (%32,3 evet ve %67,7 hayır ve S16’ da ise (%3,2 evet ve %96,8 hayır hayır cevaplarının oranı evet cevabına göre yüksek bulunurken diğer soruların cevaplarında evet oranı yüksek bulunmuştur. Öğün aralarında çocuğun isteklerinin karşılanmaması, çocuğun acıkınca yemek yedirilmemesi, çocuğun her gün düzenli olarak akşam yemeği yememesi aile bireylerinin çocuk besleme bilgisinde yetersiz olduğu düşünülmektedir. Bununla birlikte otistik çocukların cips, gazlı içecekler, lahmacun-pide türü gıdalara az yer verilmesi ve süt ve süt ürünleri, yumurta, kuru baklagiller ekmek ve makarna gibi yiyeceklere yönelmesi olumlu bir beslenme alışkanlığını göstermektedir.

  9. PREFACE: 5th Workshop of Young Researchers in Astronomy & Astrophysics

    Science.gov (United States)

    Forgács-Dajka, Emese; Plachy, Emese; Molnár, László

    2010-04-01

    The 5th Workshop of Young Researchers in Astronomy and Astrophysics was held on 2-4 September 2009 at the Eötvös University in Budapest, Hungary. This meeting fits into a conference series which can already be considered a tradition where the younger generation has the opportunity to present their work. The event was also a great opportunity for senior astronomers and physicists to form new connections with the next generation of researchers. The selection of invited speakers concentrated on the researchers currently most active in the field, mostly on a post-doctoral/tenure/fresh faculty position level. A number of senior experts and PhD students were also invited. As the conference focused on people rather than a specific field, various topics from theoretical physics to planetology were covered in three days. The programme was divided into six sections: Physics of the Sun and the Solar System Gravity and high-energy physics Galactic and extragalactic astronomy, cosmology Celestial mechanics and exoplanets Infrared astronomy and young stars Variable stars We had the pleasure of welcoming 10 invited review talks from senior researchers and 42 contributed talks and a poster from the younger generation. Participants also enjoyed the hospitality of the pub Pál at the Pálvölgyi-cave after giving, hearing and disputing countless talks. Brave souls even descended to the unbuilt, adventurous Mátyásvölgyi-cave. Memories of the conference were shadowed though. Péter Csizmadia, one of our participants and three other climbers attempted a first ever ascent to the Ren Zhong Feng peak in Sichuan, China, but they never returned from the mountains. Péter departed to China shortly after the conference, with best wishes from participants and friends. We dedicate this volume to his memory. The organisers thankthe Physics Doctoral School of Eötvös University for its hospitality. The workshop was supported by the Mecenatúra and Polányi Mihály Programmes of the National

  10. Size-controlled fabrication of zein nano/microparticles by modified anti-solvent precipitation with/without sodium caseinate

    OpenAIRE

    Li, Feng; Chen, Yan; Liu, Shubo; Qi, Jian; Wang, Weiying; Wang, Chenhua; Zhong, Ruiyue; Chen, Zhijun; Li, Xiaoming; Guan, Yuanzhou; Kong, Wei; Zhang, Yong

    2017-01-01

    Feng Li,1 Yan Chen,1,2 Shubo Liu,1 Jian Qi,1 Weiying Wang,1 Chenhua Wang,1 Ruiyue Zhong,1 Zhijun Chen,1 Xiaoming Li,1 Yuanzhou Guan,1 Wei Kong,1,2 Yong Zhang1,2 1National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 2Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China Abstract: Zein-based nano/microparticles have been demonstrated to be promising carr...

  11. Borsa İstanbul Gelişen İşletmeler Piyasası’nda İşlem Gören Firmaların Gri İlişkisel Analiz ile Performans Ölçümü

    Directory of Open Access Journals (Sweden)

    Hakan BEKTAŞ

    2013-09-01

    Full Text Available Bu çalışmada, Borsa İstanbul Gelişen İşletmeler Piyasası’nda işlem gören on bir işletme için performans ölçümü yapılmıştır. Bunun için işletmelerin, 2011 yılı bilanço ve gelir tablosu verilerinden yararlanılarak altı tane oran elde edilmiştir. Bu oranlar kullanılarak Gri İlişkisel Analiz uygulanmıştır. Analiz sonucunda, Denge Yatırım Holding A.Ş. (DENGE’nin en yüksek performansa sahip olduğu sonucuna ulaşılmıştır. Ayrıca DENGE’nin net kar/toplam varlık, net kar/özsermaye ve net kar/net satışlar olmak üzere karlılık oranlarında yüksek değerlere sahip olduğu görülmüştür.

  12. Algorithms for Large-Scale Astronomical Problems

    Science.gov (United States)

    2013-08-01

    Magana, Ross O’Connell, Xiaoying Xu, and Feng Yu . They are very nice and provided a lot of useful information. During these years I have worked with...Sicun Gao, Fan Guo, Yunchuan Kong, Ni Lao, Lei Li, Nan Li, Jialiu Lin, Yuefeng Lin, Xi Liu, Ning Lu, Min Luo, Kai Ren, Chao Shen, Long Qin, Huimin... Hsieh , Deborah A. Wallach, Mike Burrows, Tushar Chandra, Andrew Fikes, and Robert E. Gruber. Bigtable: A distributed storage system for structured data

  13. Renúncia de arrecadação fiscal: subsídios para discussão e formulação de uma política pública Tax expenditures on health care: contributions toward a public policy agenda

    Directory of Open Access Journals (Sweden)

    Maria de Fátima Siliansky de Andreazzi

    2007-01-01

    Full Text Available Este trabalho pretende investigar diversos aspectos relacionados aos incentivos governamentais que permitem o abatimento de parte dos gastos das famílias e empresas com assistência à saúde no imposto de renda. Como tais incentivos são deduzidos da renda tributável das pessoas físicas e do lucro tributável das pessoas jurídicas, a arrecadação fiscal do Estado é forçosamente reduzida. Segundo estimativa da Secretaria da Receita Federal, o valor desta renúncia, considerando as despesas com planos de saúde e os desembolsos diretos com assistência médico-hospitalar, girou em torno de R$ 2,8 bilhões em 2005. Em um quadro de subfinanciamento crônico do SUS, esta problemática será discutida à luz da eqüidade do financiamento e dos conflitos de interesse evidenciados no setor saúde.The work discusses the tax incentives with private medical expenses to families and workers in Brazil. The estimate presented by the Federal Fiscal Authority is R$ 2,8 billions in 2005. Initially, a review of concepts about the matter is performed that stressed the lack of consensus in the academic community, about the meaning of tax expenditures. It discussed, also, the relations between this fiscal policy and demand to private health insurance. After, the article presents the results of a documental research concerning political positions of relevant Brazilian social actors found in the 2000's. The discussion pointed to problems of equity and conflicts of interests that are involved with the changes in the rules that discipline these incentives.

  14. In Deep Memory of Mr.Zhao Feng%深切怀念赵沨同志

    Institute of Scientific and Technical Information of China (English)

    杜鸣心

    2004-01-01

    赵沨同志突然逝世,令人非常意外。之前我还与原中央芭蕾舞剧团演员徐谦根同志相约去他的新家拜望,未能预料这样匆匆过世,使我们失去了一位亲切的长者。

  15. A Method of Mapping Burned Area Using Chinese FengYun-3 MERSI Satellite Data

    Science.gov (United States)

    Shan, T.

    2017-12-01

    Wildfire is a naturally reoccurring global phenomenon which has environmental and ecological consequences such as effects on the global carbon budget, changes to the global carbon cycle and disruption to ecosystem succession. The information of burned area is significant for post disaster assessment, ecosystems protection and restoration. The Medium Resolution Spectral Imager (MERSI) onboard FENGYUN-3C (FY-3C) has shown good ability for fire detection and monitoring but lacks recognition among researchers. In this study, an automated burned area mapping algorithm was proposed based on FY-3C MERSI data. The algorithm is generally divided into two phases: 1) selection of training pixels based on 1000-m resolution MERSI data, which offers more spectral information through the use of more vegetation indices; and 2) classification: first the region growing method is applied to 1000-m MERSI data to calculate the core burned area and then the same classification method is applied to the 250-m MERSI data set by using the core burned area as a seed to obtain results at a finer spatial resolution. An evaluation of the performance of the algorithm was carried out at two study sites in America and Canada. The accuracy assessment and validation were made by comparing our results with reference results derived from Landsat OLI data. The result has a high kappa coefficient and the lower commission error, indicating that this algorithm can improve the burned area mapping accuracy at the two study sites. It may then be possible to use MERSI and other data to fill the gaps in the imaging of burned areas in the future.

  16. Computing the Feng-Rao distances for codes from order domains

    DEFF Research Database (Denmark)

    Ruano Benito, Diego

    2007-01-01

    We compute the Feng–Rao distance of a code coming from an order domain with a simplicial value semigroup. The main tool is the Apéry set of a semigroup that can be computed using a Gröbner basis.......We compute the Feng–Rao distance of a code coming from an order domain with a simplicial value semigroup. The main tool is the Apéry set of a semigroup that can be computed using a Gröbner basis....

  17. Ivi-Els Schneider : "Eestis on oma feng-shui täiesti olemas"

    Index Scriptorium Estoniae

    2005-01-01

    Sisearhitekt Ivi-Els Schneider (sünd. 1945) endast, eelistustest interjööri kujundamisel, kodukujundamisest, loodusega arvestamisest. Ivi-Els Schneiderist, esinemisest näitustel, omistatud preemiad, olulisemaid kujundatud objekte, loomingut muuseumides. Ill.: Ivi-Els Schneideri värv. portree

  18. Architectural Education Adapting to Climate Challenges in Light of "Feng-Shui"

    Science.gov (United States)

    Xu, Ping

    2016-01-01

    Weather challenges have become a significant issue for our society in recent years. Thousands of people have lost their homes and lives. Buildings designed without taking into account wind and water factors have repeatedly been destroyed during natural disasters. These problems in practice reflect the weak points in education. Our ancestors…

  19. VizieR Online Data Catalog: Are infrared dark clouds really quiescent? (Feng+, 2016)

    Science.gov (United States)

    Feng, S.; Beuther, H.; Zhang, Q.; Henning, T.; Linz, H.; Ragan, S.; Smith, R.

    2016-05-01

    All fits files are molecular line integrated intensity maps in G28.34S, IRDC18530, IRDC18306, and IRDC 18308 (Fig.3 in the paper). The maps unit is the intensity integrations (Kkm/s) over the velocity dispersion of each line. For the lines with <4σ detections, we only integrate a total of three channels around the system Vlsr at their rest frequencies. Files are named as "source"+"species"+".fits". G28.34S is abbreviated as "28", IRDC18306 is abbreviated as "06", IRDC18308 is abbreviated as "08", and IRDC18530 is abbreviated as "30". (2 data files).

  20. VizieR Online Data Catalog: HD20794 HARPS radial velocities (Feng+, 2017)

    Science.gov (United States)

    Feng, F.; Tuomi, M.; Jones, H. R. A.

    2017-05-01

    HARPS radial velocities, activity indices and differential radial velocities for HD 20794. The HARPS spectra are available in the European Southern Observatory archive, and are processed using the TERRA algorithm (Anglada-Escude and Butler, 2012, Cat. J/ApJS/200/15). (1 data file).

  1. VizieR Online Data Catalog: Stellar encounters with long-period comets (Feng+, 2015)

    Science.gov (United States)

    Feng, F.; Bailer-Jones, C. A. L.

    2016-07-01

    We have conducted simulations of the perturbation of the Oort cloud in order to estimate the significance of known encounters in generating long-period comets. We collected the data of stellar encounters from three sources: (Bailer-Jones, 2015, Cat. J/A+A/575/A35, hereafter BJ15), Dybczynski & Berski (2015MNRAS.449.2459D), and Mamajek et al. (2015ApJ...800L..17M). Following BJ15, we use the term 'object' to refer to each encountering star in our catalogue. A specific star may appear more than once but with different data, thus leading to a different object. (1 data file).

  2. Unexpected dehydrogenation behaviors of the 2LiBH4-MgH2 composite confined in a mesoporous carbon scaffold

    CSIR Research Space (South Africa)

    Wang, K

    2014-11-01

    Full Text Available Chemistry C Vol. 118(46) Unexpected Dehydrogenation Behaviors of the 2LiBH4−MgH2 Composite Confined in a Mesoporous Carbon Scaffold Kuikui Wang,†,‡ Xiangdong Kang,*,‡ Yujie Zhong,‡ Chaohao Hu,§ Jianwei Ren,⊥ and Ping Wang*,‡ †University... of Science and Technology of China, Hefei 230026, P. R. China ‡Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, P. R. China §Guangxi Key Laboratory of Information Materials...

  3. Ingeniørens rolle ved skabelse af innovative koncepter

    DEFF Research Database (Denmark)

    McAloone, Tim C.

    2007-01-01

    sågar også konkurrencer for skolebørn. En af årsagerne til konkurrencerne, er, at mange virksomheder anser konceptudviklingsaktiviteten for værende af stigende vigtighed. Det er interessant at bemærke, når man studerer disse forskellige konkurrencers rammer, regler og mål, at fællesnævneren for alle...... "innovative koncepter"? Først vedrørende en forståelse af "innovation" i den industrielle kontekst. Udover den relativt sikre og simplistiske definition af: innovation = opfindelse + markedsmæssig succes, er der kun ganske få forsøg i den danske industrikontekst på at definere målene for, eller aktiviteterne...... skabt (kerne produktindhold). Indtil videre er der ikke blevet leveret nogle af disse pc?er, så den kan stadig betragtes som et koncept. Men man har i hvert fald gjort sit bedste for at overveje alle teknologiske, sociale og design-aspekter af konceptet. Moralen her er, at vi ingeniører skal skærpe...

  4. Klinik, Therapie und Langzeitverlauf des hypophysären Riesenwuchses

    OpenAIRE

    Seidt, Monika, geb. Sauter

    2005-01-01

    Anhand von 24 retrospektiv analysierten Fällen mit hypophysärem Riesenwuchs aus 14 verschiedenen Kliniken innerhalb der letzten 3,5 Jahrzehnte werden die klinische Symptomatik, die endokrinologische und bildgebende Diagnostik und die gewählten Therapieansätze mit ihren Langzeitverläufen verglichen und diskutiert. Gegenwärtige Therapie der Wahl ist die selektive operative Resektion des Wachstumshormon-produzierenden Hypophysenadenomes, gegebenenfalls ergänzt durch eine medikamentöse Behandlung...

  5. Entreprenøren som figur under neoliberalismen

    DEFF Research Database (Denmark)

    Langergaard, Luise Li

    2016-01-01

    as a movement of the economic into previously non-economic domains, such as the welfare state and society. Social entrepreneurship is an example of this in relation to solutions to social welfare problems. This can, on the one hand, be understood as an extension of the neoliberal understanding...

  6. Vejledning i entreprenørens miljøgennemgang

    DEFF Research Database (Denmark)

    Amini, Rene Bo; Christensen, Knud

    1998-01-01

    The publication includes a description and a IT-tool which can be used in the initial analysis of a constuction companys environmental situation.It followes the guidelines in ISO 14001 and EU´s EMAS.......The publication includes a description and a IT-tool which can be used in the initial analysis of a constuction companys environmental situation.It followes the guidelines in ISO 14001 and EU´s EMAS....

  7. Stimmen des Leis, schillernde Gewebe / Christoph Schlüren

    Index Scriptorium Estoniae

    Schlüren, Christoph

    1995-01-01

    Baltische Werke für Streichorchester: Vol. 1: Balakauskas: Ostrobothnian Symphony, Vasks: Symphonie "Stimmen", Narbutaite: Opus Lugubre; Vol. 2: Kutavicius: Nothern Gates, Vasks: Cantabile, Tüür: Insula Deserta, Rekasius: Music for strings, Werke von Urbaitis und Juozapaitis; Ostrobothnian Chamber Orchestra, Dirigent: Juha Kangas; Finlandia / east-west CD-s 4509-97892-2 und 4509-97893-2. Vasks: Cantabile, Englischhorn-Konzert, Botschaft, Musica dolorosa, Lauda; Riga Philarmonic Orchestra, Dirigent: Kriss Rusmanis; Confer / BMG 75605-51236-2. Eller: Morgenrot, Abendrot, 5 Stücke für Streicher, Geister, Im Schatten und im Sonnenlicht, Elegia; Estonian Symphony Orchestra, Dirigent: Peeter Lilje; Forte FD 0020/2. Tubin: 11. Symphonie, Elegie für Streicher, Raid: 2. Symphonie; Estnisches Staatliches Symphonieorchester, Dirigent: Arvo Volmer; Koch 3-7291-2 H1. Sumera: Symphonien 1-3; Malmö Symphony Orchestra, Dirigent: Paavo Järvi; BIS/Disco-Center 660. Sumera: Klavierkonzert, 4. Symphonie, Musica tenera; Malmö Symphony Orchestra, Dirigent: Paavo Järvi; BIS/Disco-Center 690. Tormis: Werke für Männerchor; Estnischer Nationaler Männerchor, Dirigent: Olev Oja; Forte CDs FD 0011/2 und FD 0019/2 Tutvustatakse uusi heliplaate Baltimaade heliloojate loomingust.

  8. Antikkens veje til renæssancens Danmark

    DEFF Research Database (Denmark)

    , og vi møder foruden Petrarca blandt andre også den store humanist Erasmus af Rotterdam, den danske professor Erasmus Lætus, der skrev digte på latin, og kong Christian IV, der udsmykkede Frederiksborg Slot efter antikke idealer. Alle trak de på antikken som forbillede for at kunne opfylde deres egne...

  9. The Correspondence of René Descartes: 1643

    NARCIS (Netherlands)

    Verbeek, T.; Bos, E.-J. (Erik-Jan); Ven, Jeroen van de

    2003-01-01

    There is little disagreement that the standard edition of Descartes by Charles Adam and Paul Tannery (1897-1913, known as AT) should be redone, in any case as far as the correspondence is concerned. The reason is not only that its chronology is defective and that in its latest reprint the

  10. René Descartes, Specimina philosophiae. Introduction and Critical Edition

    NARCIS (Netherlands)

    Vermeulen, C.L.

    2007-01-01

    The Specimina philosophiae (Amsterdam: Elzevier, 1644) are preceded by a notice in which Descartes authorizes the text as a faithful translation of his Discours and Essais, and announces that he has made some changes in the original content. This raises questions about the nature, extent and

  11. Revisors opklaring af besvigelser - Læren af praksis

    DEFF Research Database (Denmark)

    Bloch Christensen, Maria; Kristensen, Rikke Holmslykke; Warming-Rasmussen, Bent

    ansvarsfordelingen. Er det bestyrelsen, direktionen, controllerne eller navnlig den eksterne revisor, som burde have opdaget besvigelsen? Eller burde selskabets medarbejdere have påtaget sig det sociale ansvar at agere som whistleblowers? De berørte parter undskylder sig ofte ved, at den nu afslørede bedrager...... medarbejdere med socialt ansvar (whistleblowers), men også de eksterne, herunder kreditgivere, offentlige kontrolmyndigheder samt økonomiske journalister....

  12. Hiina tervendus / kommenteerivad Anne, Julia, Weihong Song, Fagang Ren

    Index Scriptorium Estoniae

    2013-01-01

    Tallinnas Tulika 19 asuvast Bai Lan Hiina massaažisalongist, kus ravitakse kuputeraapia, gua sha kraapimisplaatide, moksa, nõelravi ja punktmassaaži abil. Tui na massaaži ja hiina loodusteraapia protseduure kommenteerivad spetsialistid ning patsiendid Anne ja Julia

  13. Genetics Home Reference: REN-related kidney disease

    Science.gov (United States)

    ... 2 Related Information How are genetic conditions and genes named? Additional Information & Resources MedlinePlus (5 links) Encyclopedia: Hyperkalemia Encyclopedia: Renin Health Topic: Anemia Health Topic: Gout Health Topic: Kidney Diseases Additional NIH Resources (2 ...

  14. René Girad y la paradoja de la modernidad

    OpenAIRE

    Garagalza, Luis

    2007-01-01

    El trabajo analiza la naturaleza paradójica de la modernidad occidental, por una parte, el Estado nacional, la ciencia y el mercado, las grandes instituciones modernas, se despliegan como dispositivos de pacificación para acabar con las guerras de religión que asolaron Europa al final de la edad media, pero, por otra parte, tales maquinarias creadas para acabar con el miedo crean a su vez nuevos implantes del miedo, la espantosa Shoah, que ponen en cuestión las premisas anteriores. El autor i...

  15. La seriedad en la obra de Sören Kierkegaard

    OpenAIRE

    Rivas Carreras, Víctor Rafael

    2015-01-01

    A La seriedad en la obra de Kierkegaard, “obra” es diu de dues maneres: obra primera, obra en sentit estricte, la producció literària (pel que fa a la serietat) de K.; i obra segona, la serietat de K., aquella que, sense excloure l’obra primera, constitueix la vida tota de K. Obra viscuda i vida en obra, ambdues inescindibles. És el propi d’autor per a qui no pot donar-se l’admirar sense imitar allò admirat (sense perdre amb això la pròpia primitivitat), la doctrina sense l’acció de les obre...

  16. ren er faldet langt fra stammen

    DEFF Research Database (Denmark)

    Haarder, Jon Helt

    2013-01-01

    Roman: Hassan Preislers vellykkede debutroman udleverer ikke bare multikulti-industrien. Den er også en rablende diagnosticering af det moderne menneskes livsvilkår HASSAN PREISLER BRUN MANDS BYRDE 224 sider, 249,95 Lindhardt og Ringhof Er udkommet 4......Roman: Hassan Preislers vellykkede debutroman udleverer ikke bare multikulti-industrien. Den er også en rablende diagnosticering af det moderne menneskes livsvilkår HASSAN PREISLER BRUN MANDS BYRDE 224 sider, 249,95 Lindhardt og Ringhof Er udkommet 4...

  17. Mozart, Karl Barth, og den kristne troslæren

    DEFF Research Database (Denmark)

    Petersen, Nils Holger

    2010-01-01

    En diskussion af Karl Barths teologiske brug af W.A.Mozart i den kirchliche Dogmatik med kontekstuel inddragelse af en til en vis grad tilsvarende overordnet diskussion af Mozart, skrevet af en samtidig musiker, den fremtrædende Mozart-dirigent Ferenc Fricsay. ......En diskussion af Karl Barths teologiske brug af W.A.Mozart i den kirchliche Dogmatik med kontekstuel inddragelse af en til en vis grad tilsvarende overordnet diskussion af Mozart, skrevet af en samtidig musiker, den fremtrædende Mozart-dirigent Ferenc Fricsay. ...

  18. Industriebroschüren zum Buch "Doing Business in Mexico"

    OpenAIRE

    Perales, MonicaC.; Zimmermann, Thomas A.

    2002-01-01

    St. Gallen: SIAW-HSG / Zürich: Lateinamerikanische Handelskammer in der Schweiz; Selling High-Quality Consumer Goods to Mexico (Download); Tools (Download); Machine Tools (Download) Pharmaceutical Products (Download); Medical and Surgical Equipment (Download); Measuring Technology and Quality Control (Download)

  19. Mollusken aus posttertiären Schichten von Celebes

    NARCIS (Netherlands)

    Schepman, M.M.

    1912-01-01

    Die im Folgenden behandelten Mollusken stammen aus der Nähe von Kajoe ragi auf Celebes, woselbst sie durch R. FENNEMA aus denselben Schichten ausgelesen wurden, aus denen früher durch J. G. DE MAN einige brachyure Krebse beschrieben sind. Es darf deswegen betreffs näherer Angaben über die Herkunft

  20. 1593-IJBCS-Article-Koffi René Dongo

    African Journals Online (AJOL)

    hp

    Impacts des effluents liquides industriels sur l'environnement urbain ... 1Laboratoire de Gestion de l'Environnement et des Risques (LAGERIS), Institut ... des déchets, sont devenues une préoccupation ... chimiques: à l'état solide ou dissous,.

  1. Karen Blixen's "The Poet" and Søren Kierkegaard's 'Gjentagelsen'

    DEFF Research Database (Denmark)

    Bunch, Mads

    2014-01-01

    attention to a reoccurring character in Kierkegaard’s production: the elderly bachelor esthete (Constantin Constantius), whom Blixen in “The Poet” exposes as a demonic, yet comical character. I will conclude by pointing out that repetition should be acknowledged as an integral part of Blixen’s poetics...

  2. R--en programpakke til statistisk databehandling og grafik

    DEFF Research Database (Denmark)

    Dessau, Ram Benny; Pipper, Christian Bressen

    2008-01-01

    An introduction to the R project for statistical computing (www.R-project.org) is presented. The main topics are: 1. To make the professional community aware of "R" as a potent and free software for graphical and statistical analysis of medical data; 2. Simple well-known statistical tests...

  3. Durchführung der universitären Prüfungen im klinischen Abschnitt des Medizinstudiums nach den Leitlinien des GMA-Ausschusses Prüfungen: Eine Bestandsaufnahme der medizinischen Fakultäten in Baden-Württemberg [Implementation of assessments according to the guidelines of the GMA: A survey of the medical faculties in Baden-Württemberg

    Directory of Open Access Journals (Sweden)

    Jünger, Jana

    2010-08-01

    rztlichen Approbationsordnung im Jahr 2002 wurde bundesweit ein Reformprozess in Gang gesetzt, mit dem Ziel, das Medizinstudium an den Universitäten praxisorientierter zu gestalten und eine Qualitätssicherung im Bereich der Lehre zu etablieren. Um hierbei die medizinischen Fakultäten Baden-Württembergs zu unterstützen, wurden fünf Kompetenzzentren an den medizinischen Fakultäten des Landes gegründet, die sich zum Kompetenznetz Lehre Baden-Württemberg zusammengeschlossen haben.Das Kompetenznetz Lehre hat an den fünf medizinischen Fakultäten Baden-Württembergs eine Befragung zum Umsetzungsstatus der in der GMA-Leitlinie für fakultätsinterne Leistungsnachweise dargelegten Anforderungen an qualitativ hochwertige Prüfungen im klinischen Abschnitt des Medizinstudiums durchgeführt. Um den vordringlichen Bedarf für die Unterstützung der medizinischen Fakultäten des Landes Baden-Württemberg bei der Umsetzung der Leitlinien durch das Kompetenznetz Lehre zu ermitteln, wurde eine Priorisierung der nächsten Aufgaben bei der Verbesserung der Qualität der universitären medizinischen Prüfungen vorgenommen.Es zeigte sich, dass wesentliche Teile des in den Leitlinien formulierten Anforderungskatalogs bereits erfüllt wurden oder wenigstens mittelfristig an den Fakultäten umsetzbar sind. Festgestellt wurde aber, dass die Etablierung strukturierter Reviewprozesse bei der Prüfungsvorbereitung und insbesondere der Nachbereitung noch auf deutliche Schwierigkeiten stößt. Im Rahmen einer Fokusgruppenanalyse wurden als vorrangige Arbeitsziele für das Kompetenznetz Lehre die Unterstützung der medizinischen Fakultäten für den Begutachtungsprozess der Prüfungsaufgaben („Review“, die Erstellung eines Gesamtprüfungsprogramms und von Prüfungsberichten mit statistischer Auswertung definiert. Einen weiteren Schwerpunkt bildet die Qualifizierung von Prüfungsverantwortlichen zum Thema Prüfungen.Die Ergebnisse decken sich im Wesentlichen mit einer ähnlichen Befragung der medizinischen

  4. His Excellency Mr Ken WU Ambassador Extraordinary and Plenipotentiary of the People’s Republic of China to Switzerland

    CERN Multimedia

    Jean Claude Gadmer

    2011-01-01

    Photo 1-5:The delegation visiting the ATLAS visitor Center with P.Jenni, ATLAS Collaboration former Spokesperson Photo 6-14,15-20:visiting the ATLAS experimental area Photo 15:Y. YANG,Attaché-Q. WAN,First Secretary-Z. Ren,ATLAS Collaboration,High Energy Group,Shandong University-H.E. Mr K. Wu-P. Jenni-R. Voss,Adviser for the People’s Republic of China-H. FENG,Counsellor Photo 21-38:Signature of the Guest Book with CERN Director-General R. Heuer

  5. TABLE OF CINTENTS and ABSTRACTS reprinted from ACTA PHYSICA SINICA,Vol.50,No.6(2001)(in Chinese)

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@0000 GENERAL 0330 Conservation Laws of Relativistic Variable Mass Systems…………………………… Fang Jian-hui (1005) 0340 Simulation of Shock Waves Using a Lattice Boltz mann Equation Model …………………… Feng Shi-de, Michihisa Tsutahara (1010) 0365 Double-Wave Function of RLC Circuit After Quantization…………………… Long Chao-yun, Liu Bo (1014) 0420 The Nernst Theorem and Statistical Entropy of the Scalar field in Reissner-Nordstrom Geometry……………………Zhao Ren, Zhang Li-chun (1018)

  6. Single-mode Laser by Parity-time Symmetry Breaking

    Science.gov (United States)

    2014-11-21

    solenoid -like Pds5B that reside in direct proximity to Wapl and the Smc3-Scc1 in- teraction interface (fig. S13), implying that Wapl and Pds5 control the...accepted 26 September 2014 10.1126/science.1256904 REPORTS ◥ OPTICS Single-mode laser by parity-time symmetry breaking Liang Feng,1* Zi Jing Wong,1...Ren-Min Ma,1* Yuan Wang,1,2 Xiang Zhang1,2† Effective manipulation of cavity resonant modes is crucial for emission control in laser physics and

  7. Technology Education and Technology Teacher Education in Taiwan, R.O.C. = Zhong Hua Min Guo Ke Ji Jiao Yu Ji qi shi zi Jiao Yu.

    Science.gov (United States)

    Lee, Lung-Sheng Steven; Wang, Cheng-Pin Peter; Wang, Yen-chao; Shih, Neng-Mu; Yeh, Chung-ching

    Technology education in Taiwan begins with craft work at the elementary school level, and the most important point is the practical application. All junior high school students are required to take the Living Technology course. Content includes technology and life, information and communication, construction and manufacturing, and energy and…

  8. Exploring different social media users from the millennials’ generation: a cross-cultural behavioral analysis of brazilian users of Facebook and chinese users of RenRen

    OpenAIRE

    Park, Bruno

    2015-01-01

    With the increasing importance of digital communication and its distinct characteristics, marketing tools and strategies adopted by companies have changed dramatically. Among the many digital marketing tools and new media channels available for marketers, the phenomenon known as social media is one of the most complex and enigmatic. It has a range that still is quite unexplored and deeply transforms the present view on the promotion mix (Mangold & Faulds, 2009). Conversations among users ...

  9. Naar een betere bescherming van champignonrassen : het definiëren van afgeleid kwekersrecht voor champignons en het creëren van draagvlak

    NARCIS (Netherlands)

    Sonnenberg, A.S.M.; Baars, J.J.P.

    2013-01-01

    1. Inleiding In 1980 zijn de eerste hybride rassen van de champignon gemaakt en op de markt gebracht: Horst U1 en Horst U3. Deze rassen zijn in 3 jaar uitgegroeid tot de belangrijkste ch ampignonrassen, wereldwijd. Beide rassen zijn ook de eerste paddenstoelrassen die via kwekersrecht zijn

  10. Tubin: Sinfonie nr. 11 (ergänzt von Kaljo Raid) / Christoph Schlüren

    Index Scriptorium Estoniae

    Schlüren, Christoph

    1997-01-01

    Uuest heliplaadist "Tubin: Sinfonie nr. 11 (ergänzt von Kaljo Raid); Pärt: Nekrolog op. 5, Sinfonie nr. 1; Tüür: Searching for Roots, Insula deserta, Zeitraum. Königliches Philharmonisches Orchester Stockholm, Paavo Järvi". Virgin/EMI CD 5 45212 2 (WD:71'34") DDD

  11. Late Ordovician brachiopod distribution and ecospace partitioning in the Tvären crater system, Sweden

    DEFF Research Database (Denmark)

    Frisk, Åsa M.; Harper, David Alexander Taylor

    2013-01-01

    of the guild structure of the fauna permits explanation of a local biodiversity hotspot in otherwise low-diversity strata elsewhere in the Scandinavian region. The Tvaren impact event had an important palaeobiologic effect upon the fossil record as it served as a local pump and reservoir for biodiversity....... Moreover the development of new community types and narrowly-defined niches helped further drive both a and p biodiversity during a critical phase of the Great Ordovician Biodiversification Event (C) 2012 Elsevier B.V. All rights reserved....

  12. SiRen: Leveraging Similar Regions for Efficient and Accurate Variant Calling

    Science.gov (United States)

    2015-05-30

    Cloudera, EMC2, Ericsson, Facebook, Guavus, HP, Huawei, Informatica , Intel, Microsoft, NetApp, Pivotal, Samsung, Schlumberger, Splunk, Virdata and VMware...EMC2, Ericsson, Facebook, Guavus, HP, Huawei, Informatica , Intel, Microsoft, NetApp, Pivotal, Samsung, Schlumberger, Splunk, Virdata and VMware

  13. MboI RFLP at the human renin (ren) gene locus

    Energy Technology Data Exchange (ETDEWEB)

    Masharani, U; Frossard, P M

    1988-03-25

    1.5kb full length human renin cDNA was isolated from a human kidney cDNA library and subcloned into pUC9. MboI (GATC) detects a single two allele polymorphism with fragments at either 1.4kb or 1.0kb. The frequency was studied in 80 unrelated North American. The human renin gene was assigned to chromosome 1 by southern blot analysis of DNA from human-rodent somatic cell hybrids. Codominant segregation was observed in 1 family (7 individuals).

  14. Ren et al., Afr J Tradit Complement Altern Med. (2012) 9(4):574-583

    African Journals Online (AJOL)

    AJTCAM

    room with controlled temperature (22 ± 2 °C) for 12 h light/dark cycle with free access to food and water. ... centrifuged (2500 rpm, 10 min) and the supernatant was prepared for PGE2 and protein detection. ... Current signals were low-pass filtered ... between a pipette and DRG membrane was facilitated by applying a weak ...

  15. Ein Este im revolutionären Paris / Otto-Heinich Elias

    Index Scriptorium Estoniae

    Elias, Otto-Heinrich, 1932-

    2012-01-01

    Kirjanik August von Kotzebue ja tema eestlasest teenri reisist Saksamaale ja Prantsusmaale 1790. aastal ning reisisündmustest inspireeritud romaanist "Pikk-Hans" (Der Lange Hans", 1793), milles ta omakorda parodeerib Voltaire ühte kuulsaimat teost Candide'i

  16. Qualitative Forschung mit lebenslimitierend erkrankten Kindern und Jugendlichen: Hören wir richtig hin?

    Directory of Open Access Journals (Sweden)

    Claudia Oetting-Roß

    2016-05-01

    Full Text Available Der nachfolgende Beitrag diskutiert die Herausforderungen des Einbezugs von betroffenen Kindern und Jugendlichen in die qualitative Forschung zum Thema lebenslimitierende Erkrankungen insbesondere unter dem Blickwinkel der methodischen Gestaltung dieses Einbezugs. Hierfür wird zunächst die Lebens- und Versorgungssituation lebenslimitierend erkrankter Kinder und Jugendlicher dargestellt. Anschließend werden Ergebnisse aus empirischen Studien erläutert und im Hinblick auf die Herausforderungen einer Beteiligung erkrankter Kinder, Jugendlicher und ihrer Familien diskutiert. Als Ergebnis dieser Analyse erfolgt eine Zusammenfassung zentraler Diskussionsstränge. Zudem werden Strategien für eine sensible Integration von schwerkranken Kindern und Jugendlichen abgeleitet und auf der Basis bestehender Erfahrungen aus qualitativen Studien konkretisiert. Vor dem Hintergrund einer laufenden Studie mit lebenslimitierend erkrankten Kindern liefert der Beitrag Anregungen für die methodische Planung, Durchführung und Evaluation von entsprechenden Forschungsvorhaben. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1602241

  17. Riigi vastutus mitteriiklike terroristlike rühmituste eest / René Värk

    Index Scriptorium Estoniae

    Värk, René, 1977-

    2012-01-01

    Riigi vastutuse olemusest ja sellest, millistel tingimustel on riik rahvusvahelise õiguse alusel vastutav mitteriiklike terroristlike rühmituste käitumise eest. Varjupaiga võimaldamisest kui vastutuse alusest

  18. George Herbert Mead and Sören Kierkegaard as theorists of the self

    DEFF Research Database (Denmark)

    Willert, Søren

    The self concepts of Mead and Kierkegaard respectively show striking similarities. A comparative analysis of the two self concepts is carried out. Similarities are indeed present at a structural level. Clear-cut differences appear when semantic deep structures of the concepts used by the two...... thinkers are included in the analysis. The observed differences are reflecting the fact that they drew their inspiration from widely divergent intellectual traditions, Kierkegaard from Christian theology, Mead from a darwinistically inspired world-view....

  19. Entwicklung und Applikation eines instationären Reifenmodells zur Fahrdynamiksimulation von Ackerschleppern

    OpenAIRE

    Ferhadbegovic, Bojan

    2009-01-01

    Die Fahrgeschwindigkeit moderner Ackerschlepper nimmt in den letzten Jahren stetig zu. Mittlerweile sind 50 km/h für Standardschlepper in Deutschland üblich. Um diese Geschwindigkeiten sicher erreichen zu können, werden die Ackerschlepper mit einer hydropneumatischen Vorderachsfederung ausgestattet. Eine Hinterachsfederung für Standardschlepper hat sich bisher aus Kostengründen nicht durchgesetzt. Die steigenden Transportanteile und das Bestreben nach weiteren Produktivitätserhöhungen erzeuge...

  20. Marketing y responsabilidad. Una aproximación ética desde René Girard

    OpenAIRE

    Gómez-Ferrer Lozano, Guillermo

    2016-01-01

    La presente tesis tiene como objeto analizar la ética aplicada al marketing desde la perspectiva de la responsabilidad bajo el presupuesto de la hermenéutica crítica. La ética del marketing supone el descubrimiento y análisis de los principios, valores y fundamentos éticos en el campo del marketing y su función dentro de las organizaciones, así como las responsabilidades del mismo en sus ámbitos de acción e influencia. Para ello, hemos respondido en la primera parte, a qué es el marketing...

  1. Når HRM sparker døren ind til fremtiden

    DEFF Research Database (Denmark)

    Holt Larsen, Henrik

    2016-01-01

    Vi er alt for beskedne of uambitiøse, når vi siger, hvad HRM kan bidrage med i fremtidens virksomheder. Mange af de generelle udfordringer, som virksomhederne står overfor, har nemlig en karakter, der gør det naturligt eller nødvendigt at sætte ind med HRM-professionalisme. Bolden ligger for vores...... fødder, så nu gælder det bare om at sparke. Artiklen beskriver nogle af de vigtigste udfordringer - og hvorfor HRM er et svar herpå....

  2. Gebändigtes Knallgas: Brennstoffzellen im mobilen und stationären Einsatz

    Science.gov (United States)

    Waidhas, Manfred; Landes, Harald

    2001-07-01

    Die Brennstoffzelle hat aus technischer Sicht einen hohen Stand erreicht. Die PEMFC konnte ihre Zuverlässigkeit in einer Reihe von Nischenanwendungen, aber auch in Form erster mobiler und dezentraler Prototypen beweisen. Die SOFC und die MCFC konnten bereits in Anlagen von 100 kW und mehr in Erprobung gehen. Um jedoch wirtschaftlich konkur-renzfähig zu den etablierten Technologien der mobilen und dezentralen Energiewandlung zu werden, muss noch eine drastische Kostenreduktion sowohl beim Brennstoffzellen-Stack als auch bei den zu seinem Betrieb notwendigen Hilfsaggregaten erreicht werden. Für Fahrzeugantriebe muss außerdem eine Antwort auf die noch offene Treibstofffrage (Infrastruktur, H2-Erzeugung und H2-Speicherung) gefunden werden.

  3. Ren et al., Afr J Tradit Complement Altern Med. (2016) 13(1):53-61 ...

    African Journals Online (AJOL)

    PROF ADEWUNMI

    Medical University, Key Laboratory of Traditional Chinese Medicine Modernization, ... Background: Fengliao-Changwei-Kang(FCK), the Chinese patent drug, is a famous ... repair by up regulating EGFR expression in gastric mucosa cell. ... The stem and leaves of Daphniphyllum calycinum and Polygonum .... Student's t-test.

  4. Writing the City: Søren Kierkegaard’s Urban Walks in Copenhagen

    DEFF Research Database (Denmark)

    Steiner, Henriette

    2011-01-01

    from architecture and geography, which have long addressed space, to disciplines that have traditionally focused upon images and language, the contributors demonstrate how integral space is to literary as well as artistic imagining and identity at the same time that they propose novel ways of capturing......The early twenty-first century is witnessing a paradigm shift across the humanities away from an obsession with language and towards an engagement with the way in which physical space is imagined. This book showcases the impact of that shift upon the work of diverse disciplines. Applying insights...

  5. Ontwikkelingen in Foodservice : online en beleving creëren nieuwe kansen voor toeleveranciers van agf

    NARCIS (Netherlands)

    Splinter, G.M.; Haaster-de Winter, van M.A.

    2015-01-01

    Het voedsellandschap is in beweging. Een ontwikkeling met grote gevolgen voor “vers” en haar toeleveranciers. Voedsel is op steeds meer (verschillende) plaatsen te koop en wordt aangeboden door verschillende aanbieders. GroentenFruit Huis wil de groenten- en fruitsector versterken en de positie van

  6. Riglyne vir waarde-opvoeding in Suid-Afrikaanse skole / Julia Alet Rens

    OpenAIRE

    Rens, Julia Alet

    2005-01-01

    Although the debate on values and values-education has been going on for several years, it is evident from literature that there is, as yet, no unanimity on what is meant by the concept 'values'. Chapter 2 (Article 1) is an attempt to clarify the confusion between various value-education related concepts, to analyse the phenomenon from an ontological perspective and to demonstrate that man's choice of terminology depends on presuppositions. Chapter 2 (Article 1) was written ...

  7. Effect of space flight factors on alfalfa seeds | Ren | African Journal ...

    African Journals Online (AJOL)

    Abstract. To explore the effect of space flight factors on the early development of alfalfa seedling, dry seeds were placed onboard a satellite for a 15-day flight. After retrieval, the ultra structure of seed coat and the chemical content of seed were tested, followed by tests for germinate ability, seedling growth, and mitotic and ...

  8. Vasspest (Elodea canadensis) og smal vasspest (Elodea nuttallii) Jæren 2006

    OpenAIRE

    Mjelde, M.

    2006-01-01

    Årsliste 2006 For å skaffe en oversikt over status for vasspest (Elodea canadensis) i Skas-Heigre-kanalen og nærliggende lokaliteter ble vannvegetasjonen i området kartlagt i 2006. Vasspest har fortsatt stor forekomst i Skas-Heigre-kanalen ved Soma, der den ble registrert første gang i 2005. Den ble ikke registrert lenger ned i kanalen, heller ikke i Grudavatn. Heller ikke i nærliggende lokaliteter ble vasspest registrert. Lokaliteten for smal vasspest (Elodea nuttallii), Fuglestadåna, ble...

  9. Ren idyll? : forbrukets betydning for bygdeutvikling med utgangspunkt i lokal mat og hytteliv

    OpenAIRE

    Vittersø, Gunnar

    2012-01-01

    Pure idyll? The importance of consumption for rural development exemplified with local food and cabin life. Rural areas are presently facing new challenges and opportunities for development. These changes are significantly due to a transition from primary industries such as agriculture, forestry and fishing towards activities influenced by consumption and recreation. In many ways, rural areas changes from spaces of production to spaces of consumption. Based on two consumption activities, loca...

  10. "...At lade hæren marchere, heste trampe og kanoner buldre"

    DEFF Research Database (Denmark)

    Rasmussen, Palle

    2012-01-01

    Karl Marx og Friedrich Engels fulgte opmærksomt med i de økonomiske og politiske udviklinger i deres samtid. Det gjaldt også konflikterne mellem Danmark og Tyskland om det slesvigske spørgsmål og krigen om dette i 1864. De publicerede ikke meget om denne konflikt, men diskuterede den i deres priv...

  11. Nitratreduktion in einem quartären Grundwasserleiter in Ostwestfalen, NRW

    Science.gov (United States)

    Wisotzky, Frank; Wohnlich, Stefan; Böddeker, Martin

    2018-06-01

    Groundwater chemistry and sediment chemistry are characterized in a catchment of a water works in the lower terrace of the river Ems, in east-Westphalia (Germany). In spite of strong nitrate input in the shallow groundwater, the nitrate concentration in the wells is very low, suggesting strong nitrate reduction. The aims of this study were to determine the type of nitrate reduction and to determine the depth of these reactions. As part of the groundwater investigation, soil samples were also used. All soil samples have low sulfide-sulfur contents but high organic-carbon contents. The shallow groundwater has nitrate concentrations up to 185 mg/l. Enhanced carbon-dioxide concentrations in the deeper part of the aquifer indicate a dominant organotrophic nitrate reduction. Data from a multi-level observation well show a 25% lithotrophic and 75% organotrophic nitrate reduction. Investigations of nitrate isotopes (δ15N-NO3-values and δ18O-NO3-values) and sulfate isotopes (δ34S-SO4-values and δ18O-SO4-values) support the findings.

  12. Hybride Lernarrangements in der universitären Weiterbildung. Das Beispiel Educational Media

    Directory of Open Access Journals (Sweden)

    Claudia de Witt

    2003-11-01

    Full Text Available Der Artikel beschreibt eine hybride Lernform, in der Online-Lernphasen mit Präsenzphasen kombiniert werden. "Educational Media" ist ein weiterbildender Masterstudiengang an der Universität Essen-Duisburg, der technische und didaktische Kenntnisse zur Medienerziehung vermittelt. Nach einer Bedarfs- und Zielgruppenanalyse wurde ein Curriculum entwickelt, das hier vorgestellt wird. Während in der Anfangszeit Präsenzphasen und Gruppenelemente (Chatforen besonders wichtig sind, steigt in späteren Phasen das Bedürfnis nach selbstgesteuerten Lernperioden. Eine intensive persönliche Betreuung durch Tutoren sowie die Anbindung an die Institution steigern die Motivation und verringern die Abbrecherquote.

  13. Online-Sprachlernberatung im universitären Kontext: Szenarien auf dem Prüfstand.

    OpenAIRE

    Saunders, Constanze

    2015-01-01

    Online Language Learning Counseling (OLLC) is a new method in language learning counseling. It employs various forms of communication (email, chat, and internet telephone) and various instruments (i. e. surveys, plans, and learning journals) in order to systematically complement and support foreign language students\\' self-directed learning and work processes between face-to-face and online advising sessions. The specific communicative conditions in OLLC lead to benefits and challenges for th...

  14. Handlen og væren. Paul Ricœurs polytetiske refleksionsteori

    DEFF Research Database (Denmark)

    Pallesen, Carsten

    erläutert, wie sich die Hermeneutik des Selbst als eine hegelsche Verschiebung der herkömmlichen Subjektsphilosophie verstehen lässt, die jedoch Hegels Begriff des absoluten Wissens durch den Begriff der Bezeugung (attestation) ersetzt. Dieser Begriff wird profiliert in einer textnahen Lektüre von Ricœurs...... Auseinandersetzung mit Husserl, Heidegger und Lévinas, in der Körper, Gewissen und der Andere als konstituierende Passivitätserfahrungen ausgelegt werden, die als solche das Verständnis des Anderssein als ontologischen Begriff für das Selbst begründen. Der fünfte Hauptteil beleuchtet die Attestationshermeneutik...... in zwei unterschiedlichen vorphilosophischen Bereichen: Psychoanalyse und Theologie. Hier wird Ricœurs Theorie der Erinnerung und sein Begriff des Gewissens in gerechtigkeitstheoretischer Perspektive erörtert, die eine gewisse Distanz zu realphilosophischen Bereichen wie z.B. Psychoanalyse und Theologie...

  15. 'Zaadoverdracht pepino onwaarschijnlijk' (interview met René van der Vlugt)

    NARCIS (Netherlands)

    Verheul, J.; Vlugt, van der R.A.A.

    2008-01-01

    Onderzoekers van Plant Research International (PRI) hebben een verdere toelichting gegeven op de eerdere uitkomsten van onderzoek naar het pepino mozaiekvirus in tomaat dat binnen het EU onderzoeksproject Pepeira plaatsvindt. Over de mogelijkheid van overdracht via zaad is een verkeerd beeld

  16. Pepino overdraagbaar via zaad (interview met René van der Vlugt)

    NARCIS (Netherlands)

    Boonekamp, G.; Vlugt, van der R.A.A.

    2008-01-01

    Zaad geoogst van planten met pepinomozaïekvirus vormt een risico voor de overdracht van het virus naar teeltbedrijven. Dit blijkt uit resultaten van het Europees onderzoeksproject Pereira. Al langer bestonden er vermoedens dat pepino met zaad wordt overgebracht. Nu blijkt inderdaad dat het virus,

  17. Die chirurgische Therapie der sekundären Peritonitis : Ein weiter andauerndes Problem

    NARCIS (Netherlands)

    van Ruler, O.; Boermeester, M. A.

    2016-01-01

    Secondary peritonitis remains associated with high mortality and morbidity rates. Treatment of secondary peritonitis is still challenging even in the era of modern medicine. Surgical intervention for source control remains the cornerstone of treatment besides adequate antimicrobial therapy and when

  18. Friedrich Nietzsche, René Girard y el «Pecado Original» del cristianismo

    OpenAIRE

    Langella, Simona

    2009-01-01

    This article analyses the interpretation held by Heidegger and Girard about the «predicted» death of God in Nietzsche. For him, God’s death is the death of the truth, since in all platonic or Christian perspective, God is the truth and the truth is divine. As Heidegger showed, it is the entire ultrasensitive world that disappears with the death of God. Regarding Heidegger’s interpretation, which does not grant Nietzsche’s antichristianism any great philosophical importance, Girard states t...

  19. På tærsklen til renæssancens teater

    DEFF Research Database (Denmark)

    Petersen, Lene Waage

    2007-01-01

    At the Threshold of Renaissance Comedy: This essay presents four of Ludovico Ariosto's prologues translated into Danish for the first time: the prologues to the prose versions of La Cassaria (1508) and I Suppositi (1509), the first prologue to La Lena (1528) and the second Prologue to Il Negroman......, focussing also on the problems of a new comic language in the vernacular and its relations to Ariosto's ideals of a literary 'volgare', based on the ideas of Bembo....

  20. René Van Huffel, un previlegiado puente con la cultura de habla francesa

    Directory of Open Access Journals (Sweden)

    Víctor Valembois

    2004-01-01

    Full Text Available Nunca lo conocí, pero su foto entre los eméritos en el Auditorio de la Facultad de Educación me picó la curiosidad: a base de entrevistas y lecturas confeccioné una biografía de un personaje cuya modesta e incompleta semblanza quizá incite a reflexionar sobre un modelo de profesorado y además sugiere, ojalá, que no solo en este caso, por la enseñanza de un idioma, sino por lo universitario bien entendido en tiempos de globalización, conviene tener una mente abierta a la interferencia cultural, al matiz filológico: confío que esta reconstrucción, no hagiográfico sino profundamente humanista, tenga valor de rescate, hacia el pasado y tenga utilidad, hacia el futuro

  1. ren Kierkegaard: Subjectivity, Irony and the Crisis of Modernity

    DEFF Research Database (Denmark)

    Stewart, Jon Bartley

    that the only model that he ever had for his work was the Greek philosopher Socrates. This book takes this statement by Kierkegaard as its point of departure. It tries to explore what Kierkegaard meant by this and to show how different aspects of his writing and argumentative strategy can be traced back...... to Socrates. The main focus is The Concept of Irony, which is a key text at the beginning of Kierkegaard’s literary career. Although it was an early work, it nevertheless played a determining role in his later development and writings. Indeed, it can be said that in it Kierkegaard laid the groundwork for much...

  2. History, Violence and Poetics: Saint-John Perse and René Char

    Directory of Open Access Journals (Sweden)

    Nathan Bracher

    1991-06-01

    Full Text Available This essay explores the parallel yet opposite stances taken both personally and textually by Perse and Char with respect to drama of World War II. While Perse remained disdainfully aloof from public affairs after the defeat and proclaimed in his poetry his solidarity with all humanity, Char explicitly linked his writing to events, yet sought to create a human space removed from history's upheavals. Striving to transcend the vicissitudes of individual existence, Perse celebrates an epic vision of history that overlooks and even condones its violence. Focusing on the inconsistent, fragmentary nature of existence, Char prevents us from having any teleological delusions concerning war.

  3. Renæssancen som inspiration for herregård og adel

    DEFF Research Database (Denmark)

    Jakobsen, Rasmus Skovgaard

    2017-01-01

    Reformationen flyttede den danske adels fokus fra nord til syd. Standen havde tidligere fokuseret på politiske, økonomiske og familiære forbindelser til de øvrige skandinaviske lande og den nordlige del af Tyskland, men reformationen i 1536 åbnede for en fornyet interesse for sprog, viden, kunst,...

  4. Feng xian tai du yu jiao yu he zhi ye xuan ze xing wei: yi ge shi yan fang fa de yan jiu an li

    NARCIS (Netherlands)

    Ding, X.; Sun, Y.; Hartog, J.

    2009-01-01

    An experimental study on risk attitude and choice behavior of education and career This paper introduces a research on risk attitude and choice behavior of education and career. Using the experimental methods, this study focuses on testing the reliability and validity of risk attitude measurement.

  5. Estimating net surface shortwave radiation from Chinese geostationary meteorological satellite FengYun-2D (FY-2D) data under clear sky.

    Science.gov (United States)

    Zhang, Xiaoyu; Li, Lingling

    2016-03-21

    Net surface shortwave radiation (NSSR) significantly affects regional and global climate change, and is an important aspect of research on surface radiation budget balance. Many previous studies have proposed methods for estimating NSSR. This study proposes a method to calculate NSSR using FY-2D short-wave channel data. Firstly, a linear regression model is established between the top-of-atmosphere (TOA) broadband albedo (r) and the narrowband reflectivity (ρ1), based on data simulated with MODTRAN 4.2. Secondly, the relationship between surface absorption coefficient (as) and broadband albedo (r) is determined by dividing the surface type into land, sea, or snow&ice, and NSSR can then be calculated. Thirdly, sensitivity analysis is performed for errors associated with sensor noise, vertically integrated atmospheric water content, view zenith angle and solar zenith angle. Finally, validation using ground measurements is performed. Results show that the root mean square error (RMSE) between the estimated and actual r is less than 0.011 for all conditions, and the RMSEs between estimated and real NSSR are 26.60 W/m2, 9.99 W/m2, and 23.40 W/m2, using simulated data for land, sea, and snow&ice surfaces, respectively. This indicates that the proposed method can be used to adequately estimate NSSR. Additionally, we compare field measurements from TaiYuan and ChangWu ecological stations with estimates using corresponding FY-2D data acquired from January to April 2012, on cloud-free days. Results show that the RMSE between the estimated and actual NSSR is 48.56W/m2, with a mean error of -2.23W/m2. Causes of errors also include measurement accuracy and estimations of atmospheric water vertical contents. This method is only suitable for cloudless conditions.

  6. Obituary for Péter Csizmadia

    Science.gov (United States)

    2010-04-01

    This conference proceedings is dedicated to the memory of our colleague and friend Péter Csizmadia a young physicist, a computer expert and one of the best Hungarian mountaineers who has been missing since the end of October 2009 and whose last scientific presentation occurred during the 5th Workshop of Young Researchers in Astronomy and Astrophysics, 2-4 September 2009, Budapest. Péter Csizmadia Péter Csizmadia 1972-2009 The accident: Péter Csizmadia, along with three other young Hungarian mountaineers (Kata Tolnay, Vera Mikolovits, and Balázs Pechtol) disappeared in China's Sichuan region near the Ren Zhong Feng peak of the Himalayas, in the early morning of 23 October 2009. A huge part of a glacier fell, resulting in an extraordinary ice and stone avalanche that covered the valley where they had their camp for the night. Neither their bodies nor their belongings were found by the ground and helicopter rescue teams. A brief CV: Péter Csizmadia was born in 1972. He received an MSc in physics (1996) and a PhD in heavy ion physics (2003) both of these degrees were issued by Eötvös University (Budapest, Hungary). At the beginning of his career his main research interest was centred around quark hadronization (1995-2005). Later he joined the relativity group of RMKI and worked on numerical simulations in general relativity, investigating problems such as cosmological inflation and gravitational collapse in general relativity (2005-2009). In 2005, Péter joined to our relativity group and started to work on the first version of a high precision adaptive mesh refinement (AMR) code, called GridRipper. He was the founder and he remained the main developer of GridRipper until his disappearance. Due to his efforts GridRipper became a fourth order precision AMR code implemented as C++/Java classes for solving hyperbolic systems of partial differential equations numerically. The already implemented and tested applications include the study of various dynamical systems

  7. 78 FR 60844 - Wooden Bedroom Furniture From the People's Republic of China: Partial Rescission of Antidumping...

    Science.gov (United States)

    2013-10-02

    ... Furniture Co., Ltd. Dorbest Ltd., Rui Feng Woodwork Co., Ltd. Aka Rui Feng Woodwork (Dongguan) Co., Ltd., Rui Feng Lumber Development Co., Ltd. Aka Rui Feng Lumber Development (Shenzhen) Co., Ltd., Fine... Fung Wooden Factory, Sun Fung Co., Shin Feng Furniture Co., Ltd., Stupendous International Co., Ltd...

  8. De la Historia a la Historieta: Yo, René Tardi, prisionero de guerra en el Stalag II B = From History to Comics: I, René Tardi, prisoner of war at Stalag II B

    Directory of Open Access Journals (Sweden)

    Carlos Vadillo

    2015-06-01

    Full Text Available La obra de Jacques Tardi ha recurrido con frecuencia a la Historia como marco de referencia para sus relatos. En su último álbum, el autor francés aprovecha las vivencias personales de su propio padre y, a partir de los testimonios escritos que éste dejó, ahonda de manera minuciosa y documentada en la experiencia de miles de soldados y oficiales franceses en los campos de prisioneros de la Alemania nazi entre 1940 y 1945. Pero, más allá de la representación detallada de este periodo tan poco tratado por la historiografía oficial francesa, Tardi hace gala de un extraordinario dominio del lenguaje del cómic y utiliza de manera magistral muchos de los recursos narrativos pertenecientes a este medio de expresión. Además, la manera en la que el autor trata la conflictiva y problemática relación con su progenitor otorga una dimensión especial a su última obra.Jacques Tardi has frequently used history as a point of reference for his stories. In his last work, the French author incorporates his own father’s personal memories, and, from the written testimonials he left behind, Tardi, painstakingly, documents the experiences of hundreds of thousands of French soldiers and officers who were held captive in Nazi prisoner of war camps between 1940 and 1945. Furthermore, in Tardi’s detailed representation of this period, which has received little coverage in official French history, he demonstrates an extraordinary mastery of the language of comics, and uses many of the narrative techniques specific to this medium. In addition, the way in which the author writes about the conflictive and problematic relationship he has with his father gives a special dimension to Tardi’s final work.

  9. Changing Climates. The Role of Renewable Energy in a Carbon-Constrained World. A Paper Prepared for REN21

    International Nuclear Information System (INIS)

    Christensen, J.; Denton, F.; Garg, A.; Kamel, S.; Pacudan, R.; Usher, E.

    2005-12-01

    The current paper on renewable energy and climate change is focused on the key characteristics of the climate change challenge, the intergovernmental action to address the challenge, and how current and future renewable energy projects can contribute to global carbon mitigation and adaptation efforts at the local level. The report presents the current and possible different future contributions that renewable energy can make. This is based on analysis of different authoritative global scenarios and their underlying assumptions, and is aimed at providing guidance on what would be required in terms of policy decisions and technological developments if renewable energy is going to significantly mitigate climate change. Although the focus is particularly on climate change and the opportunities for renewable energy, other issues are closely interlinked. Reducing GHG emissions by introducing more renewable energy, for example, will also have positive impacts on the security of energy supply, while potentially compounding the need for investment capital. The report begins with the current global energy demand and the contribution of renewable energy to meeting that demand. Next, different key internationally recognised energy development scenarios are presented from the Intergovernmental Panel on Climate Change (IPCC) and the International Energy Agency (IEA), together with selected policy scenarios of very different specific options to mitigate climate change and stabilize CO2 levels in the range of 450-550 ppm. These scenarios are presented with both high and limited penetrations of renewable energy, along with discussions of underlying assumptions leading to these different results, including comparisons of projected technology costs. Existing policies worldwide to promote renewable energy are then analysed for their relative efficiency and results. Guidance is presented on the possible policy tools governments can use to move from the stipulated 'business-as-usual' (BAU) renewable energy expansion to a level where renewable energy makes a major contribution to climate change mitigation over the coming decades. To present realistic recommendations, barriers and opportunities for such a renewable energy expansion are discussed separately. It is not possible to 'translate' the results of the global scenarios directly into requirements for policies at the national level. The aim of the section is therefore to show that action is already taking place, which can be scaled-up. Further, experiences with a wide variety of different policy tools are available, which support the realistic call for stronger policies. The financial implications and requirements related to different short and medium term 'energy futures' are then discussed with analysis of current actions and the specific challenges related to rapidly expanding the renewable energy sector. The specific role that carbon finance can play in this regard is addressed in detail. Linking the long-term forecasts directly to finance requirements or even summing up the costs over 100 years would not provide significant (or meaningful) policy insights. Focus is therefore on the trends for the longer term costs of different technologies. Because all predictions indicate that the Earth will face some level of climate change - even with urgent and decisive action on the mitigation side - the possible role that different renewable energy technologies can play to adapt or reduce the vulnerability to climate change are briefly discussed. More analysis is needed to better identify specific renewable energy contributions, although the chapter does provide some initial indications. It is important to emphasize that the scope here is to examine the contribution of renewable energy to mitigating climate change. The implicit assumption is that this will need to be considered in close connection with activities related to energy conservation and improved efficiency in both energy production and use. This understanding is also embedded in the scenario analysis presented in Chapter 3. Makin g this link explicit would merit an entirely separate investigation since energy efficiency and conservation present challenges of a different nature in terms of technologies, policies and implementation. It is therefore considered beyond the scope of this effort

  10. Changing Climates. The Role of Renewable Energy in a Carbon-Constrained World. A Paper Prepared for REN21

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, J.; Denton, F.; Garg, A.; Kamel, S.; Pacudan, R. [UNEP Risoe Centre on Energy, Climate and Sustainable Development URC, Roskilde (Denmark); Usher, E. [UNEP Energy Unit, Paris (France)

    2005-12-15

    The current paper on renewable energy and climate change is focused on the key characteristics of the climate change challenge, the intergovernmental action to address the challenge, and how current and future renewable energy projects can contribute to global carbon mitigation and adaptation efforts at the local level. The report presents the current and possible different future contributions that renewable energy can make. This is based on analysis of different authoritative global scenarios and their underlying assumptions, and is aimed at providing guidance on what would be required in terms of policy decisions and technological developments if renewable energy is going to significantly mitigate climate change. Although the focus is particularly on climate change and the opportunities for renewable energy, other issues are closely interlinked. Reducing GHG emissions by introducing more renewable energy, for example, will also have positive impacts on the security of energy supply, while potentially compounding the need for investment capital. The report begins with the current global energy demand and the contribution of renewable energy to meeting that demand. Next, different key internationally recognised energy development scenarios are presented from the Intergovernmental Panel on Climate Change (IPCC) and the International Energy Agency (IEA), together with selected policy scenarios of very different specific options to mitigate climate change and stabilize CO2 levels in the range of 450-550 ppm. These scenarios are presented with both high and limited penetrations of renewable energy, along with discussions of underlying assumptions leading to these different results, including comparisons of projected technology costs. Existing policies worldwide to promote renewable energy are then analysed for their relative efficiency and results. Guidance is presented on the possible policy tools governments can use to move from the stipulated 'business-as-usual' (BAU) renewable energy expansion to a level where renewable energy makes a major contribution to climate change mitigation over the coming decades. To present realistic recommendations, barriers and opportunities for such a renewable energy expansion are discussed separately. It is not possible to 'translate' the results of the global scenarios directly into requirements for policies at the national level. The aim of the section is therefore to show that action is already taking place, which can be scaled-up. Further, experiences with a wide variety of different policy tools are available, which support the realistic call for stronger policies. The financial implications and requirements related to different short and medium term 'energy futures' are then discussed with analysis of current actions and the specific challenges related to rapidly expanding the renewable energy sector. The specific role that carbon finance can play in this regard is addressed in detail. Linking the long-term forecasts directly to finance requirements or even summing up the costs over 100 years would not provide significant (or meaningful) policy insights. Focus is therefore on the trends for the longer term costs of different technologies. Because all predictions indicate that the Earth will face some level of climate change - even with urgent and decisive action on the mitigation side - the possible role that different renewable energy technologies can play to adapt or reduce the vulnerability to climate change are briefly discussed. More analysis is needed to better identify specific renewable energy contributions, although the chapter does provide some initial indications. It is important to emphasize that the scope here is to examine the contribution of renewable energy to mitigating climate change. The implicit assumption is that this will need to be considered in close connection with activities related to energy conservation and improved efficiency in both energy production and use. This understanding is also embedded in the scenario analysis presented in Chapter 3. Making this link explicit would merit an entirely separate investigation since energy efficiency and conservation present challenges of a different nature in terms of technologies, policies and implementation. It is therefore considered beyond the scope of this effort.

  11. Sibelius. Lemminkäinen-Legenden op. 22 Nr. 1-4 / Christoph Schlüren

    Index Scriptorium Estoniae

    Schlüren, Christoph

    1997-01-01

    Uuest heliplaadist "Sibelius. Lemminkäinen-Legenden op. 22 Nr. 1-4, Pohjolas Tochter op. 49, Nächtlicher Ritt und Sonnenaufgang op. 55; Göteborger Sinfoniker, Neeme Järvi; DG CD 453 426-2 (WD: 70'37") DDD Võrreldud: Opus 22: Segerstam (Ondine 852-2); op. 22 und 55; Paavo Järvi" (Virgin 545 213-2); op. 49: Segerstam (Chandos 8965)

  12. Sibelius. Lemminkäinen-Legenden op. 22 Nr. 1-4 / Christoph Schlüren

    Index Scriptorium Estoniae

    Schlüren, Christoph

    1997-01-01

    Uuest heliplaadist "Sibelius: Lemminkäinen-Legenden op. 22 Nr. 1-4, Nächtlicher Ritt und Sonnenaufgang op. 55, Luonnotar op. 70. Stockholm Philharmoniker / Paavo Järvi. Virgin/EMI CD 545213 2 (WD:70'22")DDD

  13. Zerstören oder Bewahren? Umgang mit kulturellem Erbe bel H. Böll und E. Loest

    Directory of Open Access Journals (Sweden)

    Helmut Galle

    2003-12-01

    Full Text Available O artigo descreve e analisa como dois importantes autores de oposição intelectual na Alemanha Ocidental (Böll e Oriental (Loest reconstroem, cada um para sua sociedade, as atitudes dominantes frente ao patrimônio cultural e arquitetônico. Em cada caso, as atitudes das elites do poder diferem daquelas dos opositores: Na RFA, o governo, em geral, preserva os monumentos, fingindo uma continuidade histórica; na RDA, o governo destrói palácios e igrejas para romper com as tradições. Os autores simpatizam com os opositores: Böll, no oeste, enfatiza a necessidade de destruir o patrimônio cultural para recuperar a função memorativa do mesmo, enquanto Loest opta pela resistência contra a política oficial da destruição no leste. A preservação de monumentos históricos é vista, em ambos os casos, em função das necessidades da geração atual, não como valor em si mesmo.

  14. Zeitlicher Verlauf der avaskulären Nekrose des Hüftkopfes bei Patienten mit Pemphigus vulgaris.

    Science.gov (United States)

    Balighi, Kamran; Daneshpazhooh, Maryam; Aghazadeh, Nessa; Saeidi, Vahide; Shahpouri, Farzam; Hejazi, Pardis; Chams-Davatchi, Cheyda

    2016-10-01

    Pemphigus vulgaris (PV) wird in der Regel mit systemischen Corticosteroiden und Immunsuppressiva behandelt. Avaskuläre Nekrose (AVN) des Hüftkopfes ist eine gut bekannte schwerere Komplikation einer Corticosteroid-Therapie. Die Charakteristika dieser schweren Komplikation bei PV sind nach wie vor unbekannt. Nicht kontrollierte, retrospektive Untersuchung aller PV-bedingten AVN-Fälle, die in einer iranischen Klinik für bullöse Autoimmunerkrankungen zwischen 1985 und 2013 diagnostiziert wurden. Anhand der Krankenakten von 2321 untersuchten PV-Patienten wurden 45 Fälle (1,93 %) von femoraler AVN identifiziert. Dreißig davon waren Männer. Das mittlere Alter bei der Diagnose der AVN betrug 47,4 ± 14,2 Jahre. Der mittlere Zeitraum zwischen der Diagnose des PV und dem Einsetzen der AVN lag bei 25,3 ± 18,3 Monaten. Mit Ausnahme von acht Fällen (17,8 %) setzte die AVN bei der Mehrheit der Patienten innerhalb von drei Jahren nach Diagnose des PV ein. Die mittlere kumulative Dosis von Prednisolon bei Patienten mit AVN betrug 13.115,8 ± 7041,1 mg. Zwischen der Prednisolon-Gesamtdosis und dem Zeitraum bis zum Einsetzen der AVN bestand eine starke Korrelation (p = 0,001). Bei Patienten mit Alendronateinnahme in der Vorgeschichte war dieser Zeitraum signifikant kürzer (p = 0,01). Die AVN ist eine schwere Komplikation einer Corticosteroid-Behandlung bei Patienten mit PV. Sie wird bei 2 % der Patienten beobachtet und tritt vor allem in den ersten drei Behandlungsjahren auf. Bei Patienten, die höhere Dosen von Prednisolon erhalten, setzt die AVN tendenziell früher ein. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  15. The spirituality of 'atheist' student in the secondary school of Athena royal of René Magritte of Lessines

    OpenAIRE

    Derjacques, Erica Agnes Rita

    2017-01-01

    This thesis analyses the spirituality of adolescent in two public schools in Belgium. The analysis is done using the book, Cultivating the spirit: How college can enhance students' inner lives by Jennifer Lindholm, Alexander and Helen Astin. The study focused on Five Spiritual Qualities: Spiritual Quest; Equanimity; Ethic of Caring; Charitable Involvement; and Ecumenical Worldview and Five Religious Qualities: Religious Commitment; Religious Engagement; Religious/Social Conservatism; Religiou...

  16. EUHOFA juhid valmistuvad juubelikongressiks / Filiep Defraye, Gerald Lipman, Sören Kühlwein Kristiansen, Sonja Saelaert ; intervjueerinud Gea Kammer

    Index Scriptorium Estoniae

    2011-01-01

    Õhtusöögivestlusest 14. mail Pärnus rahvusvahelise turismikoolide ühenduse juhtliikmetega, kes külastasid 13.-15. mail Eestit, et kooskõlastada organisatsiooni sügisel Tallinnas ja Pärnus toimuva kongressi, mille juhtmõte on Wel-being and Quality of life through Hospitality Education, programm ning tutvuda sihtkohtadega

  17. Enhet og Dannelse : En idehistorisk analyse av enhets og dannelses idealet til Bauhaus direktøren Walter Gropius

    OpenAIRE

    Hansen, Britt Hogstad

    2003-01-01

    Sammendrag Denne avhandlingen presenterer et annet bild av den tyske arkitekten og pedagogen Walter Gropius (1883-1969) enn det som har vært vanlig til nå i Norge. Ofte blir han fremstilt som en av funksjonalismens fremste representanter og en som banet vei for den moderne arkitekturen. I denne sammenheng beskrives han ofte som en som brøt fullstendig med alle tidligere tradisjoner. Denne oppgaven vil derimot forsøke å vise at han ikke brøt med tidligere tradisjoner, men at han i høyeste ...

  18. René Descartes, the Robots and the Soul in the debate between Tommaso Ceva and Guido Grandi

    Directory of Open Access Journals (Sweden)

    Alfredo Serrai

    2016-05-01

    Full Text Available Descartes outlined human intelligence as a divine gift, albeit in a system governed by universal laws of physics and mathematics. In the eighteenth century the camaldolite Guido Grandi and Tommaso Ceva, both mathematicians, had a dispute about the interpretation of the Cartesian model of human intelligence. This case provides an opportunity to retrace the path of a speculative techno-philosophical question concerning the human possibility to equipping robots with the ability to experience a self-consciousness.

  19. Paradoxo e medo da morte: dimensões tanatológicas na obra de SØren Kierkegaard

    Directory of Open Access Journals (Sweden)

    Alessandro Gonçalves Campolina

    2016-04-01

    Full Text Available A morte enquanto possibilidade é uma das questões centrais problematizadas pela filosofia existencial de Soeren A. Kierkegaard. Assumir a responsabilidade por “tornar-se o que se é”, em um mergulho corajoso nas múltiplas possibilidades da existência, parece ser a grande conquista dos que acreditam na vida, afirmando a cada instante, o apelo inadiável da decisão. Para tanto, um pensamento profundo do desespero é necessário para encontrar o paradoxo absoluto e a superação do medo da morte. A partir dos conceitos de angústia, desespero, “doença até a morte” e “mortalmente doente”, o presente estudo pretende investigar as dimensões tanatológicas que atravessam a obra do filósofo dinamarquês.

  20. Alcune osservazioni sui fenomeni dell'ansia nell'apprendimento di una lingua straniera / Vittoriano Renó

    Index Scriptorium Estoniae

    Renó, Vittoriano

    2009-01-01

    Võõrkeeleõpingutega seotud ängist. Artiklis püstitatakse hüpotees, et õppejõu informaalne suhtumine võib aidata õpilastel teadmisi omandada, sest kõrvaldaks ängitekitavad faktorid, mis on seotud õppejõu ja õpilase vahelise sotsiaalse distantsiga

  1. The influence of Immanuel Kant’s ethics on Søren Kierkegaard’s ethical stage

    OpenAIRE

    Bachmetjevas, Viktoras

    2015-01-01

    Straipsnyje analizuojamos Søreno Kierkegaard’o filosofinio personažo Teisėjo Vilhelmo etinės pažiūros. Įprastai Teisėjas Vilhelmas yra siejamas su Hegelio filosofine teorija, kurioje siektinas etinis gyvenimas yra suprantamas kaip Sittlichkeit, vyraujančių etinių bei moralinių normų laikymasis. Analizuojant S. Kierkegaard’o veikalo Arba / arba II dalį, straipsnyje kvestionuojamas tokios sąsajos pagrįstumas ir atskleidžiama, kad esama nemažai argumentų, leidžiančių permąstyti Te...

  2. Gurmaanlus ruulib / Marika Makarova ; kommenteerinud Anu Tali, René Uusmees, Tõnis Siigur, Hannes Võrno, Dimitri Demjanov

    Index Scriptorium Estoniae

    Makarova, Marika

    2010-01-01

    Tulevikutoidu konverentsil Tallinnas esinenud kuulsate kokkade Albert Adria, Fergus Hendersoni ja Claus Meyeri kokakunsti lähtekohtadest ja mõistet gurmaanlus mõtestavad lahti tuntud Eesti inimesed ja kokad

  3. Hjerneskademarkøren S100B kan mindske brugen af computertomografi ved lette hovedtraumer - sekundærpublikation

    DEFF Research Database (Denmark)

    Pedersen, Alma B; Mehnert, Frank; Overgaard, Søren

    2009-01-01

    on the use of blood transfusion was collected from the Danish Transfusion Database (DTDB). The outcome was defined as red blood cell transfusion (yes/no) within eight days of surgery. We estimated the relative risk for red blood cell transfusion (RR) and a 95% confidence interval (CI) adjusting for possible...

  4. Het creëren van legacy rond Le Grand Départ Tour de France in Utrecht

    NARCIS (Netherlands)

    Dijk, Bake; Slender, Hans; Smits, Froukje

    2016-01-01

    Onderzoek naar de waarde van sportevenementen is vooral gericht op impact, maar niet op de manieren waarop die impact tot stand is gekomen (leverage). Met het bestuderen van de leverage mechanismen van evenementen Chalip (2006, p. 113), is het doel om niet alleen de waarde van een evenement te

  5. "Alkohol und Nikotin" − Konzept und Evaluation eines interdisziplinären Wahlfachs mit OSPE im Studienabschnitt Medizin 1

    Directory of Open Access Journals (Sweden)

    Bergelt, Corinna

    2014-02-01

    Full Text Available [english] In the last decade, increasing interest has been paid to interdisciplinary and practical courses in the medical education in Germany. This report describes the implementation and outcome of a preclinical interdisciplinary elective course with a team-teaching concept developed by lecturers in medical psychology, anatomy, physiology and biochemistry. The practical orientation of the course led to the implementation of a final interdisciplinary OSPE to ensure fair consideration of the different disciplines involved in grading. Individual OSPE results correlate well with the fact that different skills are required in medical psychology compared to those required in anatomy, physiology and biochemistry. Student course evaluation and lecturers` experience indicate the success of this elective course. Its concept can be well adapted to other interdisciplinary courses.

  6. Eesti Energia lubab võlgades paberivabriku elektrita jätta / Eiris Teeveere, Päären Mardiste

    Index Scriptorium Estoniae

    Teeveere, Eiris

    2008-01-01

    Eesti Energia lülitab välja elektri Kehras asuvas Horizon Tselluloosi ja Paberivabrikus, kui võlgu tähtajaks ei maksta. Tehase sulgemine tooks kaasa 500 inimese töötuks jäämise ning reovee puhastuse lõppemise

  7. Missing Links : Ansätze, Probleme und Perspektiven einer transdisziplinären Ästhetik der Leerstelle

    NARCIS (Netherlands)

    Lippert, Florian

    2018-01-01

    The idea that works of film, literature and art provide readers and viewers with "constitutive gaps“ – to be "filled“ by the recipient, who thereby participates in the construction of meaning – has been discussed throughout the history of modern aesthetic theory. Early film theory focused on the

  8. "Kompleksitetskortet" og dets teoretiske baggrund i et naturalistisk perspektiv på socialretslæren-/metodikken

    DEFF Research Database (Denmark)

    Vangsgaard, Peter

    2015-01-01

    adequate professional practice within the field of social work that focused specifically on youth who have been subjected to unhealthy or dangerous situations in childhood. The assumption was and continues to be that this practice would improve if the law was a more integrated part of the action taken...... workers work- ing within the organizational context of the public welfare administration. The complexity map uses “legal formats” which is a well-known concept that forms a founding basis within the theory of welfare law. The legal formats must, however, find their more specific meaning and function....... As the research moved forward, it became much more clear that the legal challenge to the social worker could be described more precisely as a challenge of complexity: That social work is not only complex, it should be complex. At the same time complexity must be managed. Reality demonstrates that the measures...

  9. The corrosion of copper in pure oxygen-free water; Korrosion av koppar i ren syrefritt vatten

    Energy Technology Data Exchange (ETDEWEB)

    Moeller, Kenneth [SP Sveriges Tekniska Forskningsinstitut, Boraas (Sweden)

    2012-02-15

    The overall objective of this study was to investigate whether further growth of copper oxides occurred during the 19 years the test tube with copper wires was stored at SP. Further more detailed analyzes have been added during the investigation. These assays have not only been focused on the copper wires but also the palladium closure plate, the test tube and the water in the test tube have come to be analyzed by a variety of techniques.

  10. Air quality assessment of low emission zones in Copenhagen. [Denmark]; Luftkvalitetsvurdering af ren-luftzone i Koebenhavn

    Energy Technology Data Exchange (ETDEWEB)

    Solvang Jensen, S.; Ketzel, M.; Brandt, J.; Winther, M.; Ellermann, T.

    2012-09-15

    According to the government agreement from 2011 improved low emission zones have been identified as a measure to improve the air quality in greater Danish cities, and to ensure compliance with air quality limit values for NO{sub 2} of 40 {mu}g/m{sup 3} as an annual mean. The limit value is violated at H.C. Andersens Boulevard in Copenhagen which is one of the busiest urban streets in Denmark and a fixed air quality monitor station is also located in the street. Air quality model calculations also shows that some other busy streets in Copenhagen violate the annual air quality limit values for NO{sub 2}. The objective of the project is to assess the impacts of a number of improved low emission zone measures in Copenhagen regarding emissions and air quality with focus on NO{sub 2}. The impact assessment of different scenarios includes assessment of emissions and air quality. The assessment is carried out in great details for NO{sub 2} and to a lesser degree for PM exhaust, PM{sub 2.5} and PM{sub 10}. Since air quality assessment is resource demanding only the main scenarios are carried out with the full air quality model whereas the air quality of the scenario variants are assessed based on regression analysis between emissions and air quality in scenarios calculated with the full air quality model. (LN)

  11. PesantRen Rakyat: Perhelatan tradisi kolaboratif kaum abangan dengan kaum santri Pinggiran di desa sumberpucung kabupaten Malang Jawa timur

    Directory of Open Access Journals (Sweden)

    Mufidah Ch

    2012-12-01

    Full Text Available Pesantren is Islamic education base and the oldest Islamic tradition inheritance in Indonesia. As an alternative education institution which is known as opened publicly, that not all people can access this institution because of cultural and psychological obstacles for people who has special needs. While in the fact, people’ intention is getting higher towards this Institution. This research aims to describe people’s pesantren as the base of collaborative-cultural movement between common people (abangan and santri in order to change black-world tradition into people-based santri tradition. Through field research or case study using social definition paradigm-qualitative method, observation data collecting technique, interview and documentation, this research reveals that pesantren al Amin is a collaborative cultural realm which is very effective in making common people and santri from poor-marginal area into people-based performance of santri, local wisdom–based with multy strategic- approach of empowerment as sunan Kalijaga’s preaching model in spreading Islam in Java island. Pesantren merupakan basis pendidikan Islam dan pewaris tradisi keislaman tertua di Indonesia. Sebagai lembaga pendidikan alternatif yang dikenal terbuka, namun tidak semua masyarakat bisa mengakses pesantren yang disebabkan hambatan kultural dan psikologis bagi kelompok masyarakat yang berkebutuhan khusus. Sementara animo masyarakat terhadap pesantren sangat tinggi. Penelitian ini bertujuan mendiskripsikan pesantren rakyat sebagai basis gerakan kultural kolaboratif antara kaum abangan dengan kaum santri pinggiran, sehingga dapat mengubah tradisi dunia hitam (maksiat menjadi tradisi santri ala kerakyatan. Melalui penelitian lapangan dengan metode kualitatif berparadigma definisi sosial, menggunakan metode pengumpulan data melalui observasi, wawancara dan dokumentasi, hasil yang diperoleh adalah bahwa Pesantren Rakyat al-Amin merupakan medan budaya kolaboratif yang cukup efektif dalam menyantrikan kaum abangan dan santri pinggiran-miskin ala kerakyatan, berbasis kearifan lokal dengan pendekatan pemberdayaan  multi strategic, sebagaimana model dakwah Sunan Kalijaga ketika menyebarkan Islam di Tanah Jawa.

  12. NADPH oxidase activity and reactive oxygen species production in brain and kidney of adult male hypertensive Ren-2 transgenic rats

    Czech Academy of Sciences Publication Activity Database

    Vokurková, Martina; Rauchová, Hana; Řezáčová, Lenka; Vaněčková, Ivana; Zicha, Josef

    2015-01-01

    Roč. 64, č. 6 (2015), s. 849-856 ISSN 0862-8408 R&D Projects: GA MZd(CZ) NV15-25396A; GA ČR(CZ) GAP304/12/0259 Institutional support: RVO:67985823 Keywords : paraventricular nucleus * rostral ventrolateral medulla * renal medulla * renal cortex * oxidative stress * lipid peroxidation Subject RIV: ED - Physiology Impact factor: 1.643, year: 2015

  13. Von Lustschlössern und Spukhäusern. Raumatmosphären in Kunst, Literatur und Film

    Directory of Open Access Journals (Sweden)

    Krämer, Steffen

    2011-09-01

    Full Text Available In the baroque age the maison de plaisance – summer residence – was the symbol for the exclusive way of passing the time for the European aristocracy and upper classes. With these grand country seats the atmosphere of pleasure and amusement obtained its architectural arrangement. In modern literature and film this tradition was continued to create with architectural settings spatial atmospheres of highest symbolic expression. The most famous example of dark spatial atmospheres is the haunted house. In many ghost stories and horror films haunted houses play the leading part, and important architectural details, for instance doors, staircases or walks, are transitional elements, which evoke the different moods of fear and terror. These architectural dramaturgies are frequently based on ancient partly mythical patterns of imagination integrated in an archetypal dimension of cultural anthropology. Therefore – if positive or negative – spatial atmospheres have a deep attraction for everyone, especially in media of art, literature and film.

  14. Den oförutsägbare privatresenärens köpbeteende : inom flygtransportbranschen

    OpenAIRE

    Nyström, Martin; Wahlman, Anna

    2005-01-01

    Bakgrund: Flygtransportbranschen är hårt konkurrensutsatt genom stark etablering av lågprisbolag. Därtill har händelser såsom terrordådet i New York och SARS påverkat marknaden negativt; branschen har dessutom drabbats av förändrat kundbeteende, bland annat hos privatkunder, och flygbolagen finner det allt svårare att förutse kundernas köp. En medvetenhet om att resenärerna ser priset som en primär faktor vid val av flygbolag finns, men det har visat sig svårt att identifiera andra faktorer. ...

  15. Die FPÖ - ein Phänomen im internationalen Vergleich : Erfolg und Misserfolg des identitären Rechtspopulismus

    OpenAIRE

    Heinisch, Reinhard

    2004-01-01

    'Der Aufsatz versteht sich als Bestandsaufnahme der verzweigten Rechtspopulismusforschung. Konkret soll hier versucht werden, die Entwicklung der Haider-FPÖ als integraler Teil des neuen europäischen Rechtspopulismus zu beschreiben, dessen politische Stärken und Schwächen sich weitgehend aus den spezifischen strukturellen Eigenschaften dieses Phänomens ergeben. Nach einer eingehenden Analyse der Konvergenz rechtspopulistischer Strömungen in Richtung identitärer Programmatik wird besonders das...

  16. Messungen der fest-flüssig Grenzflächenenergie in ternären Systemen

    OpenAIRE

    Bulla, Annemarie Karin

    2012-01-01

    The main objective of this work is to point out a methodology to determine the solid-liquid interface energy sigmaSL in ternary alloy systems, mainly the Al-Cu-Ag system, and to present the results of these experiments. The solid-liquid interface energy is of major importance during phase transformation, i.e. phase nucleation, crystal growth and the final grain structure. In addition to cooling rate and chemical diffusion this quantity governs the microstructural length scale of solidificatio...

  17. Employee Assistance Program i USA och Finland åren 1995-2001 : en metautvärdering

    OpenAIRE

    Renteln, Katarina von

    2002-01-01

    Endast sammandrag. Inbundna avhandlingar kan sökas i Helka-databasen (http://www.helsinki.fi/helka). Elektroniska kopior av avhandlingar finns antingen öppet på nätet eller endast tillgängliga i bibliotekets avhandlingsterminaler. Only abstract. Paper copies of master’s theses are listed in the Helka database (http://www.helsinki.fi/helka). Electronic copies of master’s theses are either available as open access or only on thesis terminals in the Helsinki University Library. Vain tiivi...

  18. Příběhy dvou malých vodních elektráren

    Czech Academy of Sciences Publication Activity Database

    Höschl, Cyril; Dobiáš, Jiří (ed.)

    -, č. 1 (2007), s. 17-23 ISSN 1211-2046 Institutional research plan: CEZ:AV0Z20760514 Keywords : water shock * fatigue failures of screws * hydro-electric power plant Subject RIV: JR - Other Machinery

  19. La Passió segons Renée Vivien i el miratge-miracle del mirall

    Directory of Open Access Journals (Sweden)

    Rosa Cabré

    2004-01-01

    Full Text Available In this article, Rosa Cabré discusses Marçal´s novel and illustrates how, according to the author, the desire of love, which is a source of pleasure often accompanied by guilt and distress, can lead to the creation or the illusion of an absolute beauty, like poetry. She explains in what way the mirror and the mask, recurring motifs in Marçal´s work, symbolise identity and “otherness” and how these unite the real and the symbolic level. The novel contains an infinite number of mirrors, both external and internal ones, which enable the characters to see themselves reflected. This reflection is linked to feminity and to the possibilities of discovering ones own identity.

  20. Die Kritik am transzendentalen Ich: Zu Sartres und Ricœurs Heidegger-Lektüren

    Directory of Open Access Journals (Sweden)

    Yvanka B. Raynova

    2015-08-01

    According Otto Pöggeler Heidegger's main brake with Husserl consists in his rejection of the tran-scendental constitution conceived as the life of an "absolute Cogito," replaced by Heidegger by the "factual life" from which phenomenology should always begin. The author of this paper argues that the problem about the starting point of phenomenology also appears later in the debates between Heidegger and Sartre, as well as in Ricoeur's Heidegger interpretation. Thus, the aim of the article is to analyze to what extent the positions of Heidegger, Sartre, and Ricoeur contradicts or even exclude each other, and to what extent they cross or eventually complement each other. The inquiry shows that Heidegger's accusation of Sartre's forgetting of the question about the sense of being of Dasein is unjustified. Equally untenable is Sartre's critique of Heidegger, that he had bypassed the Cogito as a starting point of the existential analysis, because Sartre's transcendence of the Cogito, which pretends to involve the transphenomenal Being, cannot be derived from it and risks to fall again in the trap of "phenomenalism," which Sartre reproached to Husserl. Ricoeur's Heidegger interpretation brings clarity to this discussion by pulling together the decentration of the subject and the limits of apodicticity of the Cogito. But his elaboration of the hermeneutics of the Self contains the risk of a hyperbolization of the role of language.

  1. Løssluppen kohærens i Fredmans säng nr. 41 "Joachim uti Babylon"

    DEFF Research Database (Denmark)

    Heltoft, Lars

    2015-01-01

    Denne artikel er ment som et bud på at løse visse problemer med forståelsen af FS (Fredmans Sång) 41 som en del af de bibelske travestier i værket. Den er samtidig et bidrag til udviklingen af tekstanalytisk praksis på grundlag af tæt sproglig analyse. Den er et eksempel på hvorledes tekstforståe...

  2. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yu-Song Guo Zhong-Duo Wang Cheng-Zhong Yan Yu-Lan Zhang Jin-Nan Zheng Yuan-Min Xu Tao Du Chu-Wu Liu · More Details Fulltext PDF ... Aifu Yang Dapeng Sun Shikai Liu Ying Dong Zhong Chen Zunchun Zhou · More Details Fulltext ...

  3. RETRACTED: Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population.

    Science.gov (United States)

    Zhou, Tian-Biao; Guo, Xue-Feng; Jiang, Zongpei; Li, Hong-Yan

    2015-12-01

    The following article has been included in a multiple retraction: Tian-Biao Zhou, Xue-Feng Guo, Zongpei Jiang, and Hong-Yan Li Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population Journal of Renin-Angiotensin-Aldosterone System 1470320314563425, first published on February 1, 2015 doi: 10.1177/1470320314563425 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January

  4. Efficacy of α-blocker in improving ureteral stent-related symptoms: a meta-analysis of both direct and indirect comparison

    Directory of Open Access Journals (Sweden)

    He F

    2016-05-01

    Full Text Available Feng He, Li-bo Man, Gui-zhong Li, Ning Liu Department of Urinary Surgery, Beijing Jishuitan Hospital, Beijing, People’s Republic of China Objective: To critically evaluate the efficacy of an α-blocker in improving ureteral-stent-related symptoms and preliminarily investigate the difference between different types of α-blockers. Methods: Relevant randomized controlled trials were identified through searching PubMed, the Cochrane Library, Embase, and other sources. After quality assessment and data abstraction, direct comparison based on the Ureteral Stent-related Symptom Questionnaire (USSQ between α-blockers and control was performed by RevMan 5.3. Indirect comparison between different types of α-blockers was performed by ITC 1.0. Sensitive and subgroup analyses were used to handle important clinical factors. Results: Sixteen randomized controlled trials containing 1,489 cases were included. Compared with control, α-blockers significantly reduced the overall urinary symptom, pain index, general health index, and scores related to sexual matters, while no significant difference was found in work performance and additional problem scores. Subgroup analysis showed that the duration of stent insertion, patient’s age, stent size, and the type of α-blocker had the potential to influence the outcomes. Through indirect comparison, we found alfuzosin and terazosin to be better than tamsulosin in pain relief and general health improvement. Conclusion: α-Blocker was effective in treating ureteral stent-related symptoms, as it improved the major indexes of USSQ post-insertion or post-removal. Alfuzosin and terazosin seemed to be better than tamsulosin, which needs further verification because of the lack of direct comparison currently. Keywords: α-blocker, tamsulosin, alfuzosin, terazosin, ureteral stent-related discomfort

  5. Toxicity evaluation of biodegradable chitosan nanoparticles using a zebrafish embryo model

    Directory of Open Access Journals (Sweden)

    Hu YL

    2011-12-01

    Full Text Available Yu-Lan Hu1, Wang Qi1, Feng Han2, Jian-Zhong Shao3, Jian-Qing Gao11Institute of Pharmaceutics, College of Pharmaceutical Sciences, 2Institute of Pharmacology, Toxicology and Biochemical Pharmaceutics, 3College of Life Sciences, Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaBackground: Although there are a number of reports regarding the toxicity evaluation of inorganic nanoparticles, knowledge on biodegradable nanomaterials, which have always been considered safe, is still limited. For example, the toxicity of chitosan nanoparticles, one of the most widely used drug/gene delivery vehicles, is largely unknown. In the present study, the zebrafish model was used for a safety evaluation of this nanocarrier.Methods: Chitosan nanoparticles with two particle sizes were prepared by ionic cross-linking of chitosan with sodium tripolyphosphate. Chitosan nanoparticles of different concentrations were incubated with zebrafish embryos, and ZnO nanoparticles were used as the positive control.Results: Embryo exposure to chitosan nanoparticles and ZnO nanoparticles resulted in a decreased hatching rate and increased mortality, which was concentration-dependent. Chitosan nanoparticles at a size of 200 nm caused malformations, including a bent spine, pericardial edema, and an opaque yolk in zebrafish embryos. Furthermore, embryos exposed to chitosan nanoparticles showed an increased rate of cell death, high expression of reactive oxygen species, as well as overexpression of heat shock protein 70, indicating that chitosan nanoparticles can cause physiological stress in zebrafish. The results also suggest that the toxicity of biodegradable nanocarriers such as chitosan nanoparticles must be addressed, especially considering the in vivo distribution of these nanoscaled particles.Conclusion: Our results add new insights into the potential toxicity of nanoparticles produced by

  6. A rapid and highly sensitive protocol for the detection of Escherichia coli O157:H7 based on immunochromatography assay combined with the enrichment technique of immunomagnetic nanoparticles

    Directory of Open Access Journals (Sweden)

    Qi H

    2011-11-01

    Full Text Available Hui Qi1, Zhen Zhong1, Han-Xin Zhou1, Chun-Yan Deng1, Hai Zhu2, Jin-Feng Li2, Xi-Li Wang2, Fu-Rong Li1,31Clinical Medical Research Center, The Second Clinical Medical College (Shenzhen People's Hospital, Jinan University, 2Shenzhen Bioeasy Biotechnologies Co, Ltd, 3Shenzhen Institute of Gerontology, Shenzhen, People's Republic of ChinaBackground: Escherichia coli O157:H7 (E. coli O157:H7 is an important pathogenic bacterium that threatens human health. A rapid, simple, highly sensitive, and specific method for the detection of E. coli O157:H7 is necessary.Methods: In the present study, immunomagnetic nanoparticles (IMPs were prepared with nanopure iron as the core, coated with E. coli O157:H7 polyclonal antibodies. These IMPs were used in combination with immunochromatographic assay (ICA and used to establish highly sensitive and rapid kits (IMPs+ICA to detect E. coli O157:H7. The kits were then used to detect E. coli O157:H7 in 150 food samples and were compared with conventional ICA to evaluate their efficacy.Results: The average diameter of IMPs was 56 nm and the amount of adsorbed antibodies was 106.0 µg/mg. The sensitivity of ICA and IMPs+ICA was 105 colony-forming units/mL and 103 CFUs/mL, respectively, for purified E. coli O157:H7 solution. The sensitivity of IMPs+ICA was increased by two orders, and its specificity was similar to ICA.Conclusion: The kits have the potential to offer important social and economic benefits in the screening, monitoring, and control of food safety.Keywords: colloidal gold, immunomagnetic nanoparticles, Escherichia coli O157:H7, immunochromatographic assay

  7. Size-controlled fabrication of zein nano/microparticles by modified anti-solvent precipitation with/without sodium caseinate

    Directory of Open Access Journals (Sweden)

    Li F

    2017-11-01

    Full Text Available Feng Li,1 Yan Chen,1,2 Shubo Liu,1 Jian Qi,1 Weiying Wang,1 Chenhua Wang,1 Ruiyue Zhong,1 Zhijun Chen,1 Xiaoming Li,1 Yuanzhou Guan,1 Wei Kong,1,2 Yong Zhang1,2 1National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 2Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China Abstract: Zein-based nano/microparticles have been demonstrated to be promising carrier systems for both the food industry and biomedical applications. However, the fabrication of size-controlled zein particles has been a challenging issue. In this study, a modified anti-solvent precipitation method was developed, and the effects of various factors, such as mixing method, solvent/anti-solvent ratio, temperature, zein concentrations and the presence of sodium caseinate (SC on properties of zein particles were investigated. Evidence is presented that, among the previously mentioned factors, the mixing method, especially mixing rate, could be used as an effective parameter to control the size of zein particles without changing other parameters. Moreover, through fine-tuning the mixing rate together with zein concentration, particles with sizes ranging from nanometers to micrometers and low polydispersity index values could be easily obtained. Based on the size-controlled fabrication method, SC-coated zein nanoparticles could also be obtained in a size-controlled manner by incubation of the coating material with the already-formed zein particles. The resultant nanoparticles showed better performance in both drug loading and controlled release, compared with zein/SC hybrid nanoparticles fabricated by adding aqueous ethanol solution to SC solution. The possible mechanisms of the nanoprecipitation process and self-assembly formation of these nanoparticles are discussed. Keywords: zein, phase separation, microparticle, nanoparticle, encapsulation

  8. Farewell to the World, Not the History--Cherish the Memory of Comrade ZHAO Feng%溘然仙逝汗青犹在--深切缅怀赵沨同志

    Institute of Scientific and Technical Information of China (English)

    留钕铜

    2001-01-01

    @@ 前不久,突然传来赵沨同志不幸逝世的噩耗,音乐界为之震动.我们晚辈的音乐人更是为失去了这样一位博学、爱才的音乐前辈而深感痛心.我与赵沨同志的接触机会虽不多,但是他那慈

  9. Response to Commentary on Cheng, Broome, Feng, and Hu (2017) Leadership behaviours play a significant role in implementing evidence-based practice. Journal of Clinical Nursing, 2018;27:e1684-e1685.

    Science.gov (United States)

    Cheng, Lei; Feng, Sheng; Hu, Yan; Broome, Marion E

    2018-06-12

    Thank you for the opportunity to respond to Hu and Gifford's comments(Hu & Gifford, 2018). We appreciated their acknowledgement of our findings about the factors influencing the successful implementation of evidence-based practice (EBP). The authors described leadership behaviors as having a significant role in implementing evidence-based practice. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  10. RETRACTED: Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population.

    Science.gov (United States)

    Zhong, Weiqiang; Jiang, Zongpei; Zhou, Tian-Biao

    2015-12-01

    .1177/1470320314566019 Tian-Biao Zhou, Xue-Feng Guo, Zongpei Jiang, and Hong-Yan Li Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population Journal of Renin-Angiotensin-Aldosterone System 1470320314563425, first published on February 1, 2015 doi: 10.1177/1470320314563425 Chun-Hua Yang and Tian-Biao Zhou Relationship between the angiotensinogen A1166C gene polymorphism and the risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314566221, first published on February 1, 2015 doi: 10.1177/1470320314566221 Chun-Hua Yang and Tian-Biao Zhou Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression Journal of Renin-Angiotensin-Aldosterone System 1470320314568521, first published on February 3, 2015 doi: 10.1177/1470320314568521 Articles published in an issue Guohui Liu, Tian-Biao Zhou, Zongpei Jiang, and Dongwen Zheng Association of ACE I/D gene polymorphism with T2DN susceptibility and the risk of T2DM developing into T2DN in a Caucasian population Journal of Renin-Angiotensin-Aldosterone System March 2015 16: 165-171, first published on November 14, 2014 doi: 10.1177/1470320314557849 Weiqiang Zhong, Zhongliang Huang, Yong Wu, Zongpei Jiang, and Tian-Biao Zhou Association of aldosterone synthase (CYP11B2) gene polymorphism with IgA nephropathy risk and progression of IgA nephropathy Journal of Renin-Angiotensin-Aldosterone System September 2015 16: 660-665, first published on August 20, 2014 doi: 10.1177/1470320314524011.

  11. Prescriptions of Chinese herbal medicine for constipation under the national health insurance in Taiwan.

    Science.gov (United States)

    Jong, Maw-Shiou; Hwang, Shinn-Jang; Chen, Yu-Chun; Chen, Tzeng-Ji; Chen, Fun-Jou; Chen, Fang-Pey

    2010-07-01

    Constipation is a common gastrointestinal problem worldwide. The aim of this study was to determine the frequency of use and prescriptive patterns of Chinese herbal medicine (CHM) in treating constipation by analyzing the claims data of traditional Chinese medicine (TCM) from the National Health Insurance (NHI) in Taiwan. The computerized claims dataset of the TCM office visits and the corresponding prescription files in 2004 compiled by the NHI Research Institute in Taiwan were linked and processed. Visit files with the single diagnostic coding of constipation (ICD-9-CM code 564.0) were extracted to analyze the frequency and pattern of corresponding CHM prescriptions. The association rule was applied to analyze the co-prescription of CHM in treating constipation. There were 152,564 subjects who visited TCM clinics only for constipation in Taiwan during 2004 and received a total of 387,268 CHM prescriptions. Subjects between 20 and 29 years of age comprised the largest number of those treated (25.5%). Female subjects used CHM for constipation more frequently than male subjects (female:male = 3.31:1). There was an average of 4.6 items of single Chinese herbs or formula in a single prescription for constipation. Ma-zi-renwan was the most commonly prescribed herbal formula, while Da-huang (Rheum palmatum) was the most commonly used single Chinese herb. According to the association rule, the most common prescribed pattern of 2-drug combination of CHM for treating constipation was Ban-xia-xie-xin-tang plus Ma-zi-ren-wan, while the 3-drug combination of CHM was Fang-feng-tong-sheng-san, Rheum palmatum and Ma-zi-ren-wan. This study showed the pattern of single Chinese herbs or herbal formulae used in treating constipation in Taiwan. Further clinical trials are needed to evaluate the efficacy and safety of these CHMs in treating constipation. 2010 Elsevier. Published by Elsevier B.V. All rights reserved.

  12. Yi lin cuo yao(Essentials of Medical Works) and its historical materials of medical exchanges between China and Korea%朝鲜《医林撮要》所载中朝医学交流史料研究

    Institute of Scientific and Technical Information of China (English)

    梁永宣

    2001-01-01

    由朝鲜内医郑正先撰、杨礼寿校正,成书于16~17世纪时期的《医林撮要》一书,共13卷128门,它引用了大量李朝前期的朝鲜医书及当时已成书的中国医书资料,是一部非常切合临床应用的综合性方书。特别是书中所收载的“中朝质问方”和“中朝传习方”中的方剂,若干处与中国宋代医书《仁斋直指方论》等有诸多联系,是中国和朝鲜医学交流过程中的重要记录。但它与记载中朝两国政府官员之间医学质问的傅懋光《医学疑问》毫不相关。%Yi lin cuo yao,including 13 chapters and 128 categories,was written by Zheng Zhengxian and collated by Yang Lishou,both Korean imperial physicians in the 16-17th centuries.With notation of a number of the Chinese and Korean medical books and materials in the first decade of the Li dynasty,this book is a comprehensive prescription work,very useful to clinical application.Especially with several points of the formulas from Zhong chao zhi wen fang (Sino-Korean Prescriptions of Questioning) and zhong chao chuan xi fang (Sino-Korean Prescriptions of Questioning) recorded in this book connected with Ren zhai zhi zhi fang lun (Renzhai's Comprehensive Prescriptions) in the Song dynasty.This book is an important record of the exchanges on medical ideas between China and Korea.However,it has nothing to do with Yi xue yi wen (Questions on Medicine) by Fu Maoguang,which records the questions and answers between Chinese and Korean officials.

  13. Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system.

    Science.gov (United States)

    Ren, Huixia; Luo, Chuanming; Feng, Yanqing; Yao, Xiaoli; Shi, Zhe; Liang, Fengyin; Kang, Jing X; Wan, Jian-Bo; Pei, Zhong; Su, Huanxing

    2017-01-01

    Impairment of amyloid-β (Aβ) clearance leads to Aβ accumulation in the brain during the development of Alzheimer's disease (AD). Strategies that can restore or improve the clearance function hold great promise in delaying or preventing the onset of AD. Here, we show that n-3 polyunsaturated fatty acids (PUFAs), by use of fat-1 transgenic mice and oral administration of fish oil, significantly promote interstitial Aβ clearance from the brain and resist Aβ injury. Such beneficial effects were abolished in Aqp4-knockout mice, suggesting that the AQP4-dependent glymphatic system is actively involved in the promoting the effects of n-3 PUFAs on the clearance of extracellular Aβ. Imaging on clarified brain tissues clearly displayed that n-3 PUFAs markedly inhibit the activation of astrocytes and protect the AQP4 polarization in the affected brain region after Aβ injection. The results of the present study prove a novel mechanism by which n-3 PUFAs exert protective roles in reducing Aβ accumulation via mediating the glymphatic system function.-Ren, H., Luo, C., Feng, Y., Yao, X., Shi, Z., Liang, F., Kang, J. X., Wan, J.-B., Pei, Z., Su, H. Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system. © FASEB.

  14. A taxonomic revision of the silphaeformis species-group of the genus Tachinus Gravenhorst (Staphylinidae, Tachyporinae) from China.

    Science.gov (United States)

    Feng, Ting; Schülke, Michael; Li, Li-Zhen

    2013-01-01

    The Chinese species of the silphaeformis group of the genus Tachinus Gravenhorst are revised with fifteen species being treated. Thirteen of them are described as new: T. armatus Feng & Li, sp. n. (Sichuan), T. cavazzutii Feng, Li & Schülke, sp. n. (Sichuan), T. coronatus Feng, Li & Schülke, sp. n. (Ningxia, Qinghai), T. hercules Feng, Li & Schülke, sp. n. (Sichuan), T. hujiayaoi Feng, Li & Schülke, sp. n. (Shaanxi), T. jiuzhaigouensis Feng, Li & Schülke, sp. n. (Sichuan), T. linzhiensis Feng & Li, sp. n. (Tibet), T. maderianus Feng & Li, sp. n. (Sichuan), T. mengdaensis Feng, Li & Schülke, sp. n. (Qinghai), T. oblongoelytratus Feng & Li, sp. n. (Sichuan), T. parahercules Feng, Li & Schülke, sp. n. (Sichuan), T. paralinzhiensis Feng & Li, sp. n. (Tibet), and T. yini Feng, Li & Schülke, sp. n. (Sichuan). The two known species are redescribed based on the holotypes and additional material. Illustrations of the habitus and major diagnostic characters, distributional maps, and identification keys of all species are included.

  15. China’s International Behavior. Activism, Opportunism, and Diversification

    Science.gov (United States)

    2009-01-01

    assessments of their national goals, see Yan Xuetong, Guoji Zhengzhi yu Zhong - guo [International Politics and China], Beijing , China: Beijing Daxue ...Decisions: Important State Strategies After 1989], Beijing , China: Zhong - yang Dangli Chubanshe, 2004, pp. 783–806. 11 Swaine and Tellis, 2000, pp. 1–20...at the Conference on East Asian Security, Beijing , China, December 15, 2003; and Wang Yi, “Quanqiuhua Jincheng Zhong de Yazhou Quyu Hezuo” [Asian

  16. An Introduction to Human Resource Development in Taiwan, R.O.C. = Jong Hwa Min Gwo Ren Li Tz Yuan Fa Jaan Jyan Jieh.

    Science.gov (United States)

    Lee, Lung-Sheng; Chen, Ya-Yan

    In Taiwan, human resource development (HRD) is defined as the systematic education, training, and development employers provide for their employees as well as organizational development for corporations. A history of HRD development indicates that in the 1960s, the government began to implement planning measures for HRD in business and industry;…

  17. Iisraeli turvatara legaalsus : mõned kommentaarid Rahvusvahelise Kohtu ja Iisraeli kõrgeima kohtu seisukohtadele / René Värk

    Index Scriptorium Estoniae

    Värk, René, 1977-

    2005-01-01

    Rahvusvahelise Kohtu nõuandvast arvamusest ja Iisraeli kõrgeima kohtu kahest otsusest ning Iisraeli turvatara õiguspärasusest lähtuvalt rahvusvahelisest humanitaarõigusest ja ÜRO harta artiklist 51

  18. Über das Sicherstellen von Güte/Validität im Rahmen einer multi-lokalen und multidisziplinären Studie

    OpenAIRE

    Crawford, H. Ken; Leybourne, Marnie L.; Arnott, Allan

    2000-01-01

    Qualitative Forschung wird häufig wegen ihres Mangels an Güte kritisiert. Um diese Situation zu verbessern, werden in der Literatur Kriterien wie "trustworthiness", "dependability" und "reliability" diskutiert. Im vorliegenden Beitrag werden Vorschläge zu dieser Debatte ausgehend von einer empirischen Untersuchung zu den Lernprozessen von australischen Farmern gemacht. An dieser Interviewstudie, die in drei Bundesstaaten durchgeführt wurde, waren Forschende unterschiedlicher Disziplinen betei...

  19. “Over the Bridge of Sighs into Eternity.”1 On Søren Kierkegaard’s Prominent Role in the History of Melancholy

    OpenAIRE

    VERSTRYNGE, Karl

    2012-01-01

    Just as a woman who is unhappy at home spends a lot of time looking out the window, so the soul of a melancholic [Tungsindig] person keeps on the lookout for diversions. Another form of melancholy [Tungsind] is the kind which keeps its eyes shut in order to have darkness all around. (Pap. VIII1 A 239; NB2:125) It isn’t as easy as one would think to bring up the theme of melancholy and to claim something definitive about it. However one approaches it, melancholy always strongly resists any att...

  20. “Over the Bridge of Sighs into Eternity.” On Søren Kierkegaard’s Prominent Role in the History of Melancholy

    OpenAIRE

    Karl VERSTRYNGE

    2006-01-01

    Just as a woman who is unhappy at home spends a lot of time looking out the window, so the soul of a melancholic [Tungsindig] person keeps on the lookout for diversions. Another form of melancholy [Tungsind] is the kind which keeps its eyes shut in order to have darkness all around. (Pap. VIII1 A 239; NB2:125)It isn’t as easy as one would think to bring up the theme of melancholy and to claim something definitive about it. However one approaches it, melancholy always strongly resists any atte...

  1. “Over the Bridge of Sighs into Eternity.” On Søren Kierkegaard’s Prominent Role in the History of Melancholy

    Directory of Open Access Journals (Sweden)

    Karl VERSTRYNGE

    2006-06-01

    Full Text Available Just as a woman who is unhappy at home spends a lot of time looking out the window, so the soul of a melancholic [Tungsindig] person keeps on the lookout for diversions. Another form of melancholy [Tungsind] is the kind which keeps its eyes shut in order to have darkness all around. (Pap. VIII1 A 239; NB2:125It isn’t as easy as one would think to bring up the theme of melancholy and to claim something definitive about it. However one approaches it, melancholy always strongly resists any atte...

  2. Hyppige samtaler kan måske hjælpe ved svært nedsat adhærens hos belastede patienter med hiv

    DEFF Research Database (Denmark)

    Barfod, Toke Seierøe; Bergstedt, Winnie

    2013-01-01

    This pilot study investigates the feasibility and effect of an intervention based on coaching and directly observed therapy (DOT), aimed at patients who are HIV-positive and have massive adherence problems and treatment failure. Participants were followed six months with coaching, homework and DOT...

  3. Anmeldelse af Søren P. Krejler & Caroline Pontoppidan: Due diligence i praksis - med fokus på finansielle og juridiske forhold

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2012-01-01

    Artiklen anmelder det nævnte værk med særlig fokus på 1) forhold, der efterprøves ved due diligence, 2) afrapportering, 3) due diligence ved cross-border virksomhedskøb og 4) undersøgelsens sammenhæng med prisen på virksomheden.......Artiklen anmelder det nævnte værk med særlig fokus på 1) forhold, der efterprøves ved due diligence, 2) afrapportering, 3) due diligence ved cross-border virksomhedskøb og 4) undersøgelsens sammenhæng med prisen på virksomheden....

  4. Enesemääramine, lahkulöömine ja Rahvusvahelise Kohtu nõuandev arvamus Kosovo küsimuses / René Värk

    Index Scriptorium Estoniae

    Värk, René, 1977-

    2014-01-01

    17. veebruaril 2008 kuulutas Kosovo ennast iseseisvaks. Rahvusvahelise Kohtu nõuandvast arvamusest (Accordance with International Law of the Unilateral Declaration of Independence in Respect of Kosovo. Advisory Opinion, 22.07.2010. – ICJ Reports 2010, lk 403–453), et iseseisvuse väljakuulutamine ei olnud vastuolus rahvusvahelise õigusega

  5. Krankheitsverlauf, medizinische Versorgung und Lebensqualität von Patienten mit kongenitalen melanozytären Nävi - Auswertung des deutschsprachigen KMN-Registers.

    Science.gov (United States)

    Elisabeth Wramp, Maria; Langenbruch, Anna; Augustin, Matthias; Zillikens, Detlef; Krengel, Sven

    2017-02-01

    Kongenitale melanozytäre Nävi (KMN) bedeuten für Patienten und Familien eine psychologische Belastung und bergen zudem medizinische Risiken. Das 2005 gegründete deutschsprachige KMN-Register wurde nun einer Zwischenauswertung bezüglich des Krankheitsverlaufes, der medizinischen Versorgung und der Lebensqualität unterzogen. 100 Patienten, die sich in den Jahren 2005 bis 2012 mit einem Erstmeldebogen registriert hatten, wurde im Rahmen einer prospektiven Kohortenstudie Anfang 2013 ein Folgemeldebogen zugesandt. Außerdem wurden mithilfe standardisierter Fragebögen Daten zu Lebensqualität (dermatology life quality index, DLQI) und Stigmatisierungserfahrungen (perceived stigmatization questionnaire, PSQ; social comfort questionnaire, SCQ) erhoben. 83 % der Patienten oder deren Eltern antworteten (Altersdurchschnitt 11,2 Jahre, Median 6 Jahre; mittleres Follow-up 4,4 Jahre). Im Gesamtkollektiv wurden vier Melanome diagnostiziert, davon zwei zerebrale Melanome im Kindesalter, ein kutanes Melanom im Erwachsenenalter und eines, das sich als proliferierender Knoten erwies. Bei vier Kindern wurde eine neurokutane Melanozytose festgestellt, drei davon mit neurologischer Symptomatik. Chirurgisch behandelt wurden 88 % (73/83). Achtundsiebzig Prozent der Befragten berichteten eine geringe oder keine Beeinträchtigung der Lebensqualität. Die wahrgenommene Stigmatisierung beziehungsweise Beeinträchtigung des sozialen Wohlbefindens war generell ebenfalls gering. Die Ergebnisse geben einen Überblick über die Situation von Patienten mit KMN in Deutschland, Österreich und der Schweiz. Ein Melanom entwickelte sich in 3 %, eine ZNS-Beteiligung bestand in 4 % der Fälle. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  6. Moderní trendy seismického zabezpečení jaderných elektráren

    Czech Academy of Sciences Publication Activity Database

    Entler, Slavomír; Málek, Jiří; Brokešová, J.

    2017-01-01

    Roč. 25, 7-8 (2017), s. 218-224 ISSN 1210-7085 Grant - others:AV ČR(CZ) StrategieAV21/2 Program:StrategieAV Institutional support: RVO:61389021 ; RVO:67985891 Keywords : INIS * DAMPING * MECHANICAL STRUCTURES * MONITORING * NUCLEAR POWER PLANTS * REACTOR SAFETY * REINFORCED MATERIALS * SEISMIC DETECTION * SEISMIC EFFECTS * SLABS Subject RIV: JF - Nuclear Energetics; DB - Geology ; Mineralogy (USMH-B) OBOR OECD: Nuclear related engineering; Geology (USMH-B)

  7. RELACIÓN DE LA MEMORIA A CORTO PLAZO EN EL REN-DIMIENTO ACADÉ-MICO EN EDUCA-CIÓN PRIMARIA

    OpenAIRE

    Turrillo-Monte de Oca, Marcelino

    2014-01-01

    El presente estudio trata de demostrar que la memoria a corto plazo, y diversos as-pectos nutricionales/descanso, juegan un papel primordial en el proceso de enseñanza-aprendizaje, relacionándose directamente con el rendimiento académico. Para demostrar dicha relación las variables medidas son la memoria, el rendimiento académico y hábitos nutricionales/descanso. Para ello se aplicó una prueba validada ob-tenida de la batería del WISC-IV y otra de elaboración propia basada en una lista de ...

  8. Finanční analýza Třineckých železáren, a.s.

    OpenAIRE

    Havlenová, Kateřina

    2011-01-01

    This bachelor work explores the company with methods of financial analysis. From the chosen data from income statement, balance sheet and annual statements I implement ratio analysis, horizontal and vertical analysis, the balance analysis, working capital, economic value added, bankruptcy models. I also compare these information with a branch.

  9. Moderní trendy seismického zabezpečení jaderných elektráren.

    Czech Academy of Sciences Publication Activity Database

    Entler, Slavomír; Málek, Jiří; Brokešová, J.

    2017-01-01

    Roč. 67, č. 3 (2017), s. 179-184 ISSN 0375-8842 Grant - others:AV ČR(CZ) StrategieAV21/2 Program:StrategieAV Institutional support: RVO:61389021 ; RVO:67985891 Keywords : nuclear power plants * seismic safety Subject RIV: JF - Nuclear Energetics; DB - Geology ; Mineralogy (USMH-B) OBOR OECD: Nuclear related engineering; Geology (USMH-B)

  10. Politikers användande av Twitter : En studie av relationen mellan privata och offentliga samtal i den sociala sfären

    OpenAIRE

    Visuri, Anna; Arvidsson, Mirjam

    2011-01-01

    This study’s aim was to explore how the social media Twitter is used by Swedish political leaders and how they manage the relationship between having both private and public conversations in a new public sphere, the social sphere. In Sweden, studies in this area are yet to grow. We achieved our aim by responding to our three questions at the issue: What kind of content is published in each of the politicians Twitter stream? Are the politicians private or public persons on Twitter? Are the pol...

  11. Læger bør øge fokus på medicinadhærens blandt kronisk syge

    DEFF Research Database (Denmark)

    Tøttenborg, Sandra Søgaard; Topp, Marie; Ingebrigtsen, Truls Sylvan

    2014-01-01

    outcomes. Yet, no "gold standard" for assessing adherence and no consensus on what is an acceptable level exist. Physicians should be aware of non-adherence and, although it may not always be identical with the evidence-based regimen, they can facilitate good adherence by simplifying regimens and adapting...

  12. Um estudo sobre renúncia tributária e os benefícios gerados pela Zona Franca de Manaus

    Directory of Open Access Journals (Sweden)

    Romina Batista de Lucena de Souza

    2012-01-01

    Full Text Available Este artigo tem como objetivo verificar se a criação da Zona Franca de Manaustrouxe benefícios líquidos positivos para a economia de Manaus e, em certa medida,para o Estado do Amazonas. No referencial teórico utilizou-se a teoria dos polos, ateoria da base e indicadores socioeconômicos. Abordaram-se diversos aspectos daZona Franca de Manaus, como legislação, evolução histórica, resultados edificuldades. Focou-se a arrecadação tributária Federal e Estadual no Amazonas e adesoneração tributária do Governo Federal. A pesquisa caracteriza-se comoexploratória, descritiva e explicativa. Os procedimentos técnicos utilizados foram apesquisa bibliográfica e documental. A coleta de dados foi realizada pelos sites daSuframa e da Receita Federal. Os resultados indicam que as desoneraçõestributárias foram expressivas, mas menores daquelas concedidas no Sul e noSudeste; apesar disso, a arrecadação tributária no Estado do Amazonas é elevada eos custos para a sociedade desses incentivos foram menores do que os benefíciosgerados pela Zona Franca e pelo polo industrial de Manaus.Abstract This paper aims to determine whether the creation of the Free Zone of Manausbrought positive benefits to the economy of Manaus and, to some extent, for theState of Amazonas. In the theoretical reference was used the theory of the poles, thetheory of the basic and socioeconomic indicators. It addressed to various aspects ofthe Free Zone of Manaus, as legislation, historical evolution, results and difficulties. Itfocused on the Federal and State tax collection in Amazonas and tax relief in FederalGovernment. The research is characterized as exploratory, descriptive andexplanatory. The technical procedures used were the bibliographic and documentaryresearch. The data collection was performed by sites of Suframa and the ReceitaFederal. The results indicate that the tax reliefs were significant, but smaller thosegranted in South and Southeast; nevertheless, the tax collections in the State ofAmazonas is high and the cost to society of these incentives were lower than thebenefits generated by the Free Zone and by the industrial pole of Manaus.

  13. [Groups of statutory bodies and evaluation of health recovery programmes for mothers and their child(ren) - An application of a time-based break-even analysis].

    Science.gov (United States)

    Schönig, W

    2002-01-01

    Public and private expenditure in health recovery programmes for mothers and their children is stagnating. A focal point to turn around this trend is to convince the responsible statury bodies by proving both effectiveness and efficiency of these programmes. The paper suggests the application of the break-even analysis on a time-based principle. A primary calculation with the data of a major German evaluation shows significant savings if the success of the health recovery programmes holds for at least 1.19 years. Available data does not cover such a long period.

  14. Roussel. Sinfonien Nr. 3 g-Moll op. 42 und Nr. 4 A-Dur op. 5, Neeme Järvi / Christoph Schlüren

    Index Scriptorium Estoniae

    Schlüren, Christoph

    1995-01-01

    Uuest heliplaadist "Roussel. Sinfonien Nr. 3 g-Moll op. 42 und Nr. 4 A-Dur op. 53, Bacchus et Ariane op. 43 (Zweite Orchestersuite). Sinfonietta für Streichorchester d-Moll op. 52. Detroit Symphony Orchester, N. Järvi". Chandos/Koch CD 7007(WD: 70'10") DDD

  15. Pro-demokraatlik interventsioon : [bakalaureusetöö] / Rait Kaarma ; Tartu Ülikooli Õigusinstituut ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Kaarma, Rait

    2003-01-01

    Demokraatia ja rahvusvaheline õigus, õiguse demokraatiale areng, sõjalise jõu kasutamine klassikalises sõjalises õiguses, pro-demokraatliku interventsiooni doktriin, unilateraalne ja kollektiivne pro-demokraatlik interventsioon

  16. Technické památky - historie a technická řešení vodních elektráren

    OpenAIRE

    ZASADIL, Pavel

    2010-01-01

    This Bachelor work deals with the exploitation of water power as a source of energy. The first part concentrates on the history of water exploitation as a source of energy. The second part deals with water mills and their reconstruction to hydraulic water plants. The third part deals with the construction of water-wheels and hydraulic water plants. The following parts deal with the hydro-electric plants and hydraulic water plants with the calculations of efficiency of their machinery.

  17. Täna algusega kell 14 peetakse Tartu Kunstimajas sürrealismiklassiku René Magritte'i näitusega seoses ettekandepäev...

    Index Scriptorium Estoniae

    2001-01-01

    Keskendutakse sürrealismi kui mitmetasandilise nähtuse tekkeloole ja allikatele. Esinevad Frank Lanot ja Hasso Krull. Näidatakse Luis Buųeli 1928. a. valminud filmi "Andaluusia koer", mille loomises osales ka Salvador Dali. Filmi kommenteerib Lauri Kärk

  18. Riga und Tallinn wollen ihre Umweltstandards erhören : der "Zug der Ideen" faszinierte vor allem junge Menschen / Rainer Müller

    Index Scriptorium Estoniae

    Müller, Rainer

    2011-01-01

    Euroopa keskkonna-pealinn Hamburg esitleb uusi ideid Riias ja Tallinnas. Tallinnast kui Euroopa kultuuripealinnast, kultuurikilomeetrist, Tallinna avamisest merele. Linnaplaneerimise, ökoloogia ja kultuuri parimate seoste otsimisest. Euroopa Rohelise pealinna idee autori Jüri Ratase mõtteid Tallinna tulevikust

  19. Vliv větrných elektráren na percepci krajiny a životního prostředí

    Czech Academy of Sciences Publication Activity Database

    Frantál, Bohumil; Cetkovský, Stanislav; Kunc, J.

    2008-01-01

    Roč. 42, č. 6 (2008), s. 307-312 ISSN 0044-4863 R&D Projects: GA AV ČR(CZ) KJB700860801 Institutional research plan: CEZ:AV0Z30860518 Keywords : wind energy * perception * quality of life * preferences * tourism Subject RIV: AO - Sociology, Demography

  20. Maailma Kaubandusorganisatsiooni riigihankelepingu roll Euroopa Liidu riigihankeõiguses : [magistritöö] / Rahel Klaas ; Tartu Ülikool, õigusteaduskond ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Klaas, Rahel, 1986-

    2013-01-01

    Riigihangete alase regulatsiooni arengust ning ulatusest kaasaja WTO-s ja Euroopa Liidus, rahvusvahelise riigihangete alase regulatsiooni rakendajatest, GPA (Agreement on Government Procurement = GPA) tulevikuperspektiividest

  1. Verlauf der zellulären Immunantwort bei Lebendnierenempfängern - Messung von IFN-γ und IL-17 im Elispot-Assay

    OpenAIRE

    Grehn, Conrad

    2015-01-01

    Die Nierentransplantation ermöglicht Patienten die Wiederherstellung der Nierenfunktion. Aufgrund der begrenzten Verfügbarkeit an Organen nimmt dabei die Zahl der Transplantationen von einem lebenden Spender stetig zu. Zudem ermöglichen die präzisen und genauen Vorbereitungen und Abläufe bei Lebendnierenspenden eine bessere 5-Jahres-Überlebensrate als bei Kadaverspenden. Die genetische Verschiedenheit zwischen Spender und Empfänger bedingt jedoch eine lebenslange immunsuppressive Therapie, um...

  2. Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats

    Czech Academy of Sciences Publication Activity Database

    Jíchová, Š.; Kopkan, L.; Husková, Z.; Doleželová, Š.; Neckář, Jan; Kujal, P.; Vernerová, Z.; Kramer, H. J.; Sadowski, J.; Kompanowska; Jezierska, E.; Reddy, N. R.; Falck, J. R.; Imig, J. D.; Červenka, L.

    2016-01-01

    Roč. 34, č. 10 (2016), s. 2008-2025 ISSN 0263-6352 R&D Projects: GA ČR(CZ) GA15-07544S Institutional support: RVO:67985823 Keywords : epoxyeicosatrienoic acid analog * malignant hypertension * renal blood flow autoregulation * renin-angiotensin system * sodium excretion Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 4.085, year: 2016

  3. Entre a entrega e a renúncia: excelência acadêmica em escolas públicas chilenas de alta performance

    Directory of Open Access Journals (Sweden)

    Maria Luísa Quaresma

    2015-12-01

    Full Text Available Resumo A excelência é um dos conceitos-chave da nova retórica educativa. Este artigo procura refletir sobre as representações sociais de excelência partilhadas por diretores e alunos dos dois últimos anos do ensino médio de duas escolas públicas de alto rendimento localizadas em Santiago do Chile, capital de um dos países do mundo mais permeável às lógicas de mercantilização da educação. Propõe-se ainda a dar conta dos custos que a demanda da excelência envolve, em termos emocionais e de gestão dos tempos de lazer e de sociabilidade. Num primeiro momento, caracterizar-se-á o sistema educativo chileno e discutir-se-á o polissémico conceito de excelência, desde as concepções mais performativas às mais enfocadas nos projetos de formação integral. A abertura do sistema educativo do Chile à privatização, avaliação e accountabilitydeixaria prever uma forte adesão à vertente acadêmica da excelência por parte dos agentes educativos dessas escolas. No entanto, os dados recolhidos através de técnicas intensivas e extensivas (entrevistas individuais com equipes diretivas e estudantes e grupos de discussão e inquéritos por questionário com alunos revelam percepções matizadas, com os estudantes a integrarem mais vincadamente, na sua representação social de excelência, dimensões não performativistas e utilitaristas. Quanto ao modo como os alunos vivenciam a demanda da excelência, prevalecem os testemunhos de estados de ansiedade e estresse, em alguns casos de elevada gravidade, e os relatos de uma sobrecarga diária com as tarefas acadêmicas, a qual não deixa o necessário espaço para o estabelecimento das redes de sociabilidade e lazer que são parte integrante da identidade juvenil.

  4. Der Homo migrans der Früren Neuzeit. Die böhmischen Exulanten und die neuere deutsche Migrations- und Exilforschung

    Czech Academy of Sciences Publication Activity Database

    Lisá, Martina

    2011-01-01

    Roč. 49, č. 25 (2011), s. 221-240 ISSN 0231-5955 R&D Projects: GA AV ČR(CZ) IAA800090802 Institutional research plan: CEZ:AV0Z90090514 Keywords : exile, , * migration * Bohemian exiles Subject RIV: AA - Philosophy ; Religion

  5. The effects of repeated delivery of angiotensin II AT1 receptor antisense on distinct vasoactive systems in Ren-2 transgenic rats: young vs. adult animals

    Czech Academy of Sciences Publication Activity Database

    Vaněčková, Ivana; Dobešová, Zdenka; Kuneš, Jaroslav; Zicha, Josef

    2012-01-01

    Roč. 35, č. 7 (2012), s. 761-768 ISSN 0916-9636 R&D Projects: GA AV ČR(CZ) IAA500110902; GA ČR(CZ) GAP304/12/0259 Institutional support: RVO:67985823 Keywords : AT(1) receptor * BP regulation * gene therapy * oligodeoxynucleotides * vasodilator and vasoconstrictor systems Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 2.791, year: 2012

  6. Addition of ETA receptor blockade increases renoprotection provided by renin-angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats

    Czech Academy of Sciences Publication Activity Database

    Čertíková; Chábová, V.; Vernerová, Z.; Kujal, P.; Husková, Z.; Škaroupková, P.; Tesař, V.; Kramer, H. J.; Kompanowska; Jezierska, E.; Walkowska, A.; Sadowski, J.; Červenka, L.; Vaněčková, Ivana

    2014-01-01

    Roč. 118, č. 2 (2014), s. 297-305 ISSN 0024-3205 R&D Projects: GA ČR(CZ) GAP304/12/0259 Institutional support: RVO:67985823 Keywords : renal failure * 5/6 nephrectomy * renin-angiotensin * endothelin * survival Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 2.702, year: 2014

  7. Läkarens Ethos : Studier i den svenska läkarkårens identiteter, intressen och ideal 1890-1960

    OpenAIRE

    Eklöf, Motzi

    2000-01-01

    Doctors, academically educated and authorized, assert that there is more to being a real doctor than having fulfilled the formal criteria. It has been said that there is a particular doctor's ethos, which is based not only on thorough medical education but also on traditional know-how, internalized ethics and good character. This paper contains several studies of the efforts of Swedish physicians to define themselves as doctors, individually and collectively, during the period 1890-1960 and t...

  8. TÜRKİYE’DE YER DEĞİŞTİREN YERLEŞMELERE BİR ÖRNEK: ARGUVAN İLÇE MERKEZİ (MALATYA)

    OpenAIRE

    AKBULUT, GÜLPINAR

    2013-01-01

    ÖZETTürkiye’de depremler, heyelan ve sel gibi doğal olayların sonucunda yerleşmeler yer değiştirir. Heyelan nedeniyle 1966, 1977 ve 1988 yıllarında yer değiştiren Arguvan ilçesi de ülkemizde bu şekildeki yerleşmelere bir örnektir. Burada akma ve çökme şeklinde görülen kütle hareketleri nedeniyle oturulamaz hale gelen meskenlerde yaşayan insanların bir kısmı yeni yerleşim alanlarına taşınmıştır. Ancak yeni yerleşim yerinde de kütle hareketleri devam etmekte, üstelik doğal afet ve ekonominin sı...

  9. A new link between stress response and nucleolar function during pollen development in Arabidopsis mediated by AtREN1 protein

    Czech Academy of Sciences Publication Activity Database

    Reňák, David; Gibalová, Antónia; Šolcová, Katarzyna; Honys, David

    2014-01-01

    Roč. 37, č. 3 (2014), s. 670-683 ISSN 0140-7791 R&D Projects: GA ČR(CZ) GAP501/11/1462; GA ČR(CZ) GAP305/12/2611; GA MŠk(CZ) LD11018; GA MŠk(CZ) LD13049 Institutional support: RVO:61389030 Keywords : heat shock response * heat shock transcription factor * male gametophyte development Subject RIV: ED - Physiology Impact factor: 6.960, year: 2014

  10. Prescription patterns of Chinese herbal products for post-surgery colon cancer patients in Taiwan.

    Science.gov (United States)

    Chao, Te-Hsin; Fu, Pin-Kuei; Chang, Chiung-Hung; Chang, Shih-Ni; Chiahung Mao, Frank; Lin, Ching-Heng

    2014-08-08

    Traditional Chinese medicine (TCM) is commonly provided to cancer patients, however, the patterns of prescriptions for this type of medicine in Taiwan are unclear. This study aimed to evaluate the use of traditional Chinese medicine products in colon cancer patients post-surgery in Taiwan and to research patterns of TCM. This was a cross-sectional study of newly diagnosed colon cancer patients who received surgery between 2004 and 2008 identified from the National Health Insurance Research Database of Taiwan. The prescription patterns and reasons for the use of TCM for colon cancer were analyzed. The results showed that "symptoms, signs and ill-defined conditions" (23.3%) and diseases of the digestive system (16.9%) were the most common reasons for using Chinese herbal medicine. Xiang-sha-liu-jun-zi-tang (7.1%), Bu-zhong-yi-qi-tang (4.3%), Jia-wei-xiao-yao-san (4.1%), Shen-Ling-Bai-Zhu-San (3.7%), Ban-Xia-Xie-Xin-Tang (3.4%), Gui-pi-tang (2.4%), Ping-Wei-San (2.4%), Gan-Lu-Yin (2.0%), Bao-He-Wan (1.9%), and Zhen-Ren-Huo-Ming-Yin (1.8%) were the most commonly prescribed single Chinese herbal formulae (CHF) for colon cancer patients post-surgery. Hedyotis diffusa Willd (Bai Hua She She Cao) (5.1%) and Scutellaria barbata (Ban Zhi Lian )(4.8%) were the most commonly prescribed single Chinese herbs. This study identified patterns of TCM use in colon cancer patients post-surgery in Taiwan. The herbal ingredients were most commonly used for stimulate ghrelin secretion to increase food intake and had potential anti-tumor effect. However, further research is required to evaluate any beneficial effects which could identify leads for the development of new treatment strategies using TCM. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  11. Self and identity

    DEFF Research Database (Denmark)

    Grøn, Arne

    2004-01-01

    subjektivitet, selv, identitet, tidslighed, John Locke, Søren Kierkegaard, filosofisk hermeneutik......subjektivitet, selv, identitet, tidslighed, John Locke, Søren Kierkegaard, filosofisk hermeneutik...

  12. Social perspective: the missing element in mental health practice

    National Research Council Canada - National Science Library

    U'Ren, Richard C

    2011-01-01

    .... ________________________________________________________________ Library and Archives Canada Cataloguing in Publication U'Ren, Richard, 1939- Social perspective : the missing element in mental health practice / Richard U'Ren...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. LI-MIN FENG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 547-554 Article. Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway · LI-MIN FENG XUE-FENG WANG QING-XIAN ...

  14. Reference: 612 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 612 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u17513484i Feng Haizh...1531-45 17513484 2007 Jul Plant physiology Chen Qingguo|Feng Haizhong|Feng Jian|Yang Xiaohui|Zhang Jian|Zuo Jianru

  15. Põhimõttekindel kodu / Piret Veigel

    Index Scriptorium Estoniae

    Veigel, Piret, 1961-

    2011-01-01

    Merle Kauberi korterist Tehnika tänaval, kus kogu sisustus ja planeering on lähtunud feng shui põhimõtetest ning mis pälvis konkursil "Kodu Kauniks 2010" finalistidiplomi. Lk. 31-33 feng shui lähtepunktidest ja ba qua tsoonidest. Sisekujundajaks oli Kristiina Eljand ja feng shui eksperdiks Janno Seeder

  16. 76 FR 19033 - Action Affecting Export Privileges; Credit International Trading Co. Ltd; In the Matter of...

    Science.gov (United States)

    2011-04-06

    ... Zhong Guan Cun Nan Street, Haidian District, Beijing 100039, People's Republic of China and No 9A Dongtucheng Road, Heping Street, Chaoyang District, Beijing, People's Republic of China; Order Making Order.... 2 Zhong Guan Cun Nan Street, Haidian District, Beijing 100039, People's Republic of China, and No 9A...

  17. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Astrophysics and Astronomy. Liu Zhong-Bao. Articles written in Journal of Astrophysics and Astronomy. Volume 37 Issue 2 June 2016 pp 12. Stellar Spectral Classification with Locality Preserving Projections and Support Vector Machine · Liu Zhong-bao · More Details Abstract Fulltext PDF.

  18. RETRACTED: Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression.

    Science.gov (United States)

    Yang, Chun-Hua; Zhou, Tian-Biao

    2015-12-01

    This article has been included in a multiple retraction: Chun-Hua Yang and Tian-Biao Zhou Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression Journal of Renin-Angiotensin-Aldosterone System 1470320314568521, first published on February 3, 2015 doi: 10.1177/1470320314568521 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10.1177/1470320314566019 Tian-Biao Zhou, Xue-Feng Guo, Zongpei

  19. Cordelia c'est moi

    DEFF Research Database (Denmark)

    Dehs, Jørgen

    1987-01-01

    Kritik af jean Baudrillard's tolkning af Søren Kierkegaad: Forførens dagbog, som den kommer til udtryk i bogen "Forførelse".......Kritik af jean Baudrillard's tolkning af Søren Kierkegaad: Forførens dagbog, som den kommer til udtryk i bogen "Forførelse"....

  20. Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

    International Nuclear Information System (INIS)

    Zhang, Y. P.; Liu, Yi; Yuan, G. L.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R.; Luo, X. B.; Liu, Y. Q.; Hua, Y.; Isobe, M.

    2014-01-01

    A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team , Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported

  1. Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Y. P., E-mail: zhangyp@swip.ac.cn; Liu, Yi; Yuan, G. L.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R. [Southwestern Institute of Physics, P.O. Box 432, Chengdu 610041 (China); Luo, X. B.; Liu, Y. Q.; Hua, Y. [Institute of Nuclear Science and Technology, Sichuan University, Chengdu 610041 (China); Isobe, M. [National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5259 (Japan)

    2014-05-15

    A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team , Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported.

  2. Association of the miR-196a2 C>T and miR-499 A>G polymorphisms with hepatitis B virus-related hepatocellular carcinoma risk: an updated meta-analysis

    Directory of Open Access Journals (Sweden)

    Zhu SL

    2016-04-01

    Full Text Available Shao-Liang Zhu,1,* Jian-Hong Zhong,1,* Wen-Feng Gong,1,* Hang Li,2 Le-Qun Li11Department of Hepatobiliary Surgery, 2Department of Ultrasound, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, People’s Republic of China*These authors contributed equally to this workBackground: This study meta-analyzed data on the possible association of the miR-196a2 C>T (rs11614913 and miR-499 A>G (rs3746444 polymorphisms with risk of hepatitis B virus (HBV-related hepatocellular carcinoma (HCC.Methods: Databases in PubMed, EMBASE, Web of Science, China BioMedicine, and Google Scholar were systematically searched to identify relevant studies. Meta-analyses were performed to examine the association of the miR-196a2 C>T and miR-499 A>G polymorphisms with HBV-related HCC risk. Odds ratios (ORs and 95% confidence intervals (95% CIs were calculated.Results: A total of 13 studies involving 3,964 cases and 5,875 healthy controls were included. Random-effect meta-analysis showed that the T allele and TT genotype of miR-196a2 C>T were associated with significantly lower HBV-related HCC risk (allelic model, OR =0.84, 95% CI =0.71–0.99, P=0.04; homozygous model, OR =0.68, 95% CI =0.47–0.98, P=0.04. In contrast, miR-499 A>G showed no significant association with HBV-related HCC risk in either overall pooled analysis or ethnic subgroup analysis according to any of the four genetic models. Based on analysis of ethnic subgroups, neither miR-196a2 C>T nor miR-499 A>G was significantly associated with risk of HBV-related HCC in Chinese population.Conclusion: The polymorphism miR-196a2 C>T, but not miR-499 A>G, may be associated with decreased HBV-related HCC risk. These conclusions should be verified in large, well-designed studies.Keywords: microRNA, single nucleotide polymorphisms, hepatitis B virus related, meta-analysis, hepatocellular carcinoma

  3. TNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting

    Directory of Open Access Journals (Sweden)

    Chen FY

    2014-09-01

    Full Text Available Feng-Ying Chen,1 Jing-Jing Yan,1 Han-Xi Yi,2 Fu-Qiang Hu,2 Yong-Zhong Du,2 Hong Yuan,2 Jian You,2 Meng-Dan Zhao1 1Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2College of Pharmaceutical Science, Zhejiang University, Hangzhou, People’s Republic of China Abstract: Nowadays, a real challenge in cancer therapy is to design drug delivery systems that can achieve high concentrations of drugs at the target site for improved therapeutic effect with reduced side effects. In this research, we designed and synthesized a homing peptide-(TNYLFSPNGPIA, TNYL modified chitosan-g-stearate (CS polymer micelle (named T-CS for targeting delivery. The peptide displayed specific binding affinity to EphB4 which is a member of the Eph family of receptor tyrosine protein kinases. The amphiphilic polymer T-CS can gather into micelles by themselves in an aqueous environment with a low critical micelle concentration value (91.2 µg/L and nano-scaled size (82.1±2.8 nm. The drug encapsulation efficiency reached 86.43% after loading the hydrophobic drug doxorubicin (DOX. The cytotoxicity of T-CS/DOX against SKOV3 cells was enhanced by approximately 2.3-fold when compared with CS/DOX. The quantitative and qualitative analysis for cellular uptake indicated that TNYL modification can markedly increase cellular internalization in the EphB4-overexpressing SKOV3 cell line, especially with a short incubation time. It is interesting that relatively higher uptake of the T-CS/DOX micelles by SKOV3 cells (positive-EphB4 than A549 cells (negative-EphB4 was observed when the two cells were co-incubated. Furthermore, in vivo distribution experiment using a bilateral-tumor model showed that there was more fluorescence accumulation in the SKOV3 tumor than in the A549 tumor over the whole experiment. These results suggest that TNYL-modified CS micelles may be promising drug carriers as targeting therapy for the EphB4-overexpressing

  4. Preparation and characteristics of lipid nanoemulsion formulations loaded with doxorubicin

    Directory of Open Access Journals (Sweden)

    Jiang SP

    2013-08-01

    Full Text Available Sai-Ping Jiang,1,2,* Sai-Nan He,3,* Yun-Long Li,2,3 Da-Lin Feng,2 Xiao-Yang Lu,1 Yong-Zhong Du,2 He-Yong Yu,3 Fu-Qiang Hu,2 Hong Yuan2 1Department of Pharmacy, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 2College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 3Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China *These authors contributed equally to this work Purpose: Safe and effective lipid nanoemulsion (LNE formulations for the antitumor delivery of doxorubicin is designed. Methods: LNEs composed of medium-chain triglyceride, soybean oil, lecithin, and doxorubicin are prepared by a solvent-diffusion method in an aqueous system. The effects of lipid material composition and polyethylene glycol (PEGylation on the size, drug encapsulation efficiency, and stability of LNEs are investigated. Based on in-vitro cytotoxicity and cellular uptake tests of A549 (human lung carcinoma cells, in-vivo biodistribution, antitumor activity, and cardiac toxicity are further examined using nude mouse bearing A549 tumor. Results: The LNE size decreases from 126.4 ± 8.7 nm to 44.5 ± 9.3 nm with increased weight ratio of medium-chain triglyceride to soybean oil from 1:4 to 3:2, whereas the encapsulation efficiency of doxorubicin is slightly reduced from 79.2% ± 2.1% to 71.2% ± 2.9%. The PEGylation of LNE by 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(PEG2000] (DSPE-PEG 2000 does not significantly change the size and drug encapsulation efficiency. Three-month storage at room temperature and lyophilization process does not affect the drug encapsulation efficiency, whereas the size slightly increases to almost 100 nm. The in-vitro drug-release profiles of LNEs suggest that the present formulation can prolong drug release for 48 hours. LNEs can be internalized into tumor cells in vitro and efficiently accumulate in tumor tissues in vivo by passive targeting

  5. Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

    Science.gov (United States)

    Zhang, Y. P.; Liu, Yi; Luo, X. B.; Isobe, M.; Yuan, G. L.; Liu, Y. Q.; Hua, Y.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R.

    2014-05-01

    A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team, Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported.

  6. Expert consensus on acute exacerbation of chronic obstructive pulmonary disease in the People's Republic of China

    Directory of Open Access Journals (Sweden)

    Cai BQ

    2014-04-01

    Full Text Available Bai-qiang Cai,1 Shao-xi Cai,2 Rong-chang Chen,3 Li-ying Cui,4 Yu-lin Feng,5 Yu-tong Gu,6 Shao-guang Huang,7 Rong-yu Liu,8 Guang-nan Liu,9 Huan-zhong Shi,10 Yi Shi,11 Yuan-lin Song,6 Tie-ying Sun,12 Chang-zheng Wang,13 Jing-lan Wang,1 Fu-qiang Wen,5 Wei Xiao,14 Yong-jian Xu,15 Xi-xin Yan,16 Wan-zhen Yao,17 Qin Yu,18 Jing Zhang,6 Jin-ping Zheng,3 Jie Liu,6 Chun-xue Bai6 1Department of Pulmonary Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 2Southern Medical University South Hospital, Guangzhou, 3The First Affiliated Hospital of Guangzhou Medical College and Guangzhou Institute of Respiratory Diseases, Guangzhou, 4Affiliate Hospital of Inner Mongolia Medical University, Huhehaote, 5Huaxi Hospital of Sichuan University, Chendu, 6Zhongshan Hospital, Shanghai Medical College, Fudan University and Shanghai Respiratory Research Institute, Shanghai, 7Ruijing Hospital of Shanghai Jiaotong University, Shanghai, 8The First Affiliated University of Anhui Medical University, Hefei, 9The First Affiliated University of Guangxi Medical University, Nanning, 10Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 11General Hospital of Nanjing Military Region, Nanjing, 12Beijing Hospital of the Ministry of Health, Beijing, 13Xinqiao Hospital, Third Military Medical University, Chongqing, 14Qilu Hospital of Shandong University, Jinan, 15Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 16The Second Affiliated Hospital of Hebei Medical University and Hebei Research Institute of Respiratory Medicine, Shijiazhuang, 17The Third Affiliated Hospital of Beijing University, Beijing, 18The First Affiliated University of Lanzhou University, Lanzhou, People's Republic of China Abstract: Chronic obstructive pulmonary disease (COPD is a common disease that severely threatens human health. Acute exacerbation of COPD (AECOPD is a major cause of

  7. Consolidation chemotherapy improves progression-free survival in stage III small-cell lung cancer following concurrent chemoradiotherapy: a retrospective study

    Directory of Open Access Journals (Sweden)

    Chen XR

    2016-09-01

    Full Text Available Xin-Ru Chen,1,* Jian-Zhong Liang,2,* Shu-Xiang Ma,1 Wen-Feng Fang,1 Ning-Ning Zhou,1 Hai Liao,1 De-Lan Li,1 Li-Kun Chen1 1Department of Medical Oncology, 2Department of Pathology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China *These authors contributed equally to this work Background: Concurrent chemoradiotherapy (CCRT is the standard treatment for limited-stage small-cell lung cancer (LD-SCLC. However, the efficacy of consolidation chemotherapy (CCT in LD-SCLC remains controversial despite several studies that were performed in the early years of CCT use. The aim of this study was to reevaluate the effectiveness and toxicities associated with CCT. Methods: This retrospective analysis evaluated 177 patients with stage IIIA and IIIB small-cell lung cancer (SCLC who underwent CCRT from January 2001 to December 2013 at Sun Yat-Sen University Cancer Center (SYSUCC. Overall survival (OS and progression-free survival (PFS were analyzed using Kaplan–Meier methods. Univariate and multivariate analyses were performed to analyze patient prognosis factors. Results: Among the 177 patients, 72 (41% received CCT and 105 (59% did not receive CCT. PFS was significantly better for patients in the CCT group compared to that for patients in the non-CCT group (median PFS: 17.0 vs 12.9 months, respectively, P=0.031, whereas the differences in OS were not statistically significant (median OS: 31.6 vs 24.8 months, respectively, P=0.118. The 3- and 5-year OS rates were 33.3% and 20.8% for patients in the CCT group and 27.6% and 6.7% for patients in the non-CCT group, respectively. Multivariate analysis revealed that having a pretreatment carcinoembryonic antigen level <5 ng/mL (P=0.035, having undergone prophylactic cranial irradiation (P<0.001, and having received CCT (P=0.002 could serve as favorable independent prognostic factors

  8. The impact of liposomal linolenic acid on gastrointestinal microbiota in mice

    Directory of Open Access Journals (Sweden)

    Li XX

    2018-03-01

    Full Text Available Xuan-xuan Li,1 Si Shi,2 Lan Rong,1 Mei-qing Feng,2 Liang Zhong1 1Department of Digestive Diseases, Huashan Hospital Affiliated to Fudan University, Shanghai, China; 2School of Pharmacy, Fudan University, Shanghai, China Background: The prevalence of Helicobacter pylori has long been a global health issue. Triple therapy, being the first-line treatment, has caused dysbiosis of the gastrointestinal tract that led to various complications. A novel nanomedicine – liposomal linolenic acid (LipoLLA – has been proven to have great potential in eradicating H. pylori. However, the possible side effects of LipoLLA due to alteration of the gastrointestinal microbiota remain unknown.Aim: This study focused on the impact of LipoLLA on gastrointestinal microbiota in mice in comparison with triple therapy in order to assess the safety profile.Methods: Mice were divided into five groups: blank control group; H. pylori control group; triple therapy group; low-dose LipoLLA group (25 mg/kg; and high-dose LipoLLA group (50 mg/kg. Fecal samples were collected before and after the intake of corresponding formulas. Gastric tissues were obtained after mice dissection. These samples were analyzed with high-throughput sequencing.Results: The analysis revealed that LipoLLA resulted in minor gut microbiota alteration at different levels. The altered proportions in the high-dose group were higher than that of the low-dose group. On the other hand, the triple therapy group showed dramatic shifts in the major community composition. It displayed a notable boost in the relative abundance of Proteobacteria and Firmicutes along with a decrease in that of Verrucomicrobia and Bacteroidetes. All of them belonged to the major phyla in the microbiome. Triple therapy also led to the growth of the family Enterobacteriaceae, Enterococcaceae, and Clostridiaceae_1 that may be associated with clinical illnesses. Gastric microbiota analysis reached similar conclusions.Conclusion: Our

  9. Matrix-induced autologous chondrocyte implantation for the treatment of chondral defects of the knees in Chinese patients

    Directory of Open Access Journals (Sweden)

    Zhang ZW

    2014-12-01

    Full Text Available Zhongwen Zhang,1 Xin Zhong,2 Huiru Ji,1 Zibin Tang,1 Jianpeng Bai,1 Minmin Yao,1 Jianlei Hou,1 Minghao Zheng,3 David J Wood,3 Jiazhi Sun,4 Shu-Feng Zhou,4,5 Aibing Liu6 1Department of Orthopedics, General Hospital of Chinese People’s Armed Police Forces (CAPF, Beijing; 2Department of MRI Center, General Hospital of CAPF, Beijing, People’s Republic of China; 3Center for Orthopedic Research, School of Surgery and Pathology, University of Western Australia, Perth, Western Australia, Australia; 4Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA; 5Guizhou Provincial Key Laboratory for Regenerative Medicine, Stem Cell and Tissue Engineering Research Center and Sino–US Joint Laboratory for Medical Sciences, Guiyang Medical University, Guiyang, Guizhou; 6Medical Research Center, General Hospital of Chinese People’s Armed Police Forces (CAPF, Beijing, People’s Republic of China Abstract: Articular cartilage injury is the most common type of damage seen in clinical orthopedic practice. The matrix-induced autologous chondrocyte implant (MACI was developed to repair articular cartilage with an advance on the autologous chondrocyte implant procedure. This study aimed to evaluate whether MACI is a safe and efficacious cartilage repair treatment for patients with knee cartilage lesions. The primary outcomes were the Knee Injury and Osteoarthritis Outcome Score (KOOS domains and magnetic resonance imaging (MRI results, compared between baseline and postoperative months 3, 6, 12, and 24. A total of 15 patients (20 knees, with an average age of 33.9 years, had a mean defect size of 4.01 cm2. By 6-month follow-up, KOOS results demonstrated significant improvements in symptoms and knee-related quality of life. MRI showed significant improvements in four individual graft scoring parameters at 24 months postoperatively. At 24 months, 90% of MACI grafts had filled completely and 10% had good

  10. Xyloketal-derived small molecules show protective effect by decreasing mutant Huntingtin protein aggregates in Caenorhabditis elegans model of Huntington’s disease

    Directory of Open Access Journals (Sweden)

    Zeng YX

    2016-04-01

    Full Text Available Yixuan Zeng,1,2,* Wenyuan Guo,1,* Guangqing Xu,3 Qinmei Wang,4 Luyang Feng,1,2 Simei Long,1 Fengyin Liang,1 Yi Huang,1 Xilin Lu,1 Shichang Li,5 Jiebin Zhou,5 Jean-Marc Burgunder,6 Jiyan Pang,5 Zhong Pei1,2 1Department of Neurology, National Key Clinical Department and Key Discipline of Neurology, Guangdong Key Laboratory for Diagnosis and Treatment of Major Neurological Disease, The First Affiliated Hospital, Sun Yat-sen University, 2Guangzhou Center, Chinese Huntington’s Disease Network, 3Department of Rehabilitation, The First Affiliated Hospital, 4Key laboratory on Assisted Circulation, Ministry of Health, Department of Cardiovascular Medicine of the First Affiliated Hospital, 5School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 6Swiss Huntington’s Disease Center, Department of Neurology, University of Bern, Bern, Switzerland *These authors contributed equally to this work Abstract: Huntington’s disease is an autosomal-dominant neurodegenerative disorder, with chorea as the most prominent manifestation. The disease is caused by abnormal expansion of CAG codon repeats in the IT15 gene, which leads to the expression of a glutamine-rich protein named mutant Huntingtin (Htt. Because of its devastating disease burden and lack of valid treatment, development of more effective therapeutics for Huntington’s disease is urgently required. Xyloketal B, a natural product from mangrove fungus, has shown protective effects against toxicity in other neurodegenerative disease models such as Parkinson’s and Alzheimer’s diseases. To identify potential neuroprotective molecules for Huntington’s disease, six derivatives of xyloketal B were screened in a Caenorhabditis elegans Huntington’s disease model; all six compounds showed a protective effect. Molecular docking studies indicated that compound 1 could bind to residues GLN369 and GLN393 of the mutant Htt protein, forming a

  11. Menatetrenone versus alfacalcidol in the treatment of Chinese postmenopausal women with osteoporosis: a multicenter, randomized, double-blinded, double-dummy, positive drug-controlled clinical trial

    Directory of Open Access Journals (Sweden)

    Jiang Y

    2014-01-01

    Full Text Available Yan Jiang,1,* Zhen-Lin Zhang,2,* Zhong-Lan Zhang,3 Han-Min Zhu,4 Yi-Yong Wu,5 Qun Cheng,4 Feng-Li Wu,5 Xiao-Ping Xing,1 Jian-Li Liu,3 Wei Yu,6 Xun-Wu Meng11Department of Endocrinology, Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 2Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 3Department of Gynecology and Obstetrics, General Hospital of the People's Liberation Army, Beijing, 4Department of Geriatrics, Shanghai Huadong Hospital, Shanghai, 5Department of Gynecology and Obstetrics, Beijing Hospital, Ministry of Public Health, Beijing, 6Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China*These authors contributed equally to this workObjective: To evaluate whether the efficacy and safety of menatetrenone for the treatment of osteoporosis is noninferior to alfacalcidol in Chinese postmenopausal women.Method: This multicenter, randomized, double-blinded, double-dummy, noninferiority, positive drug-controlled clinical trial was conducted in five Chinese sites. Eligible Chinese women with postmenopausal osteoporosis (N=236 were randomized to Group M or Group A and received menatetrenone 45 mg/day or alfacalcidol 0.5 µg/day, respectively, for 1 year. Additionally, all patients received calcium 500 mg/day. Posttreatment bone mineral density (BMD, new fracture onsets, and serum osteocalcin (OC and undercarboxylated OC (ucOC levels were compared with the baseline value in patients of both groups.Results: A total of 213 patients (90.3% completed the study. After 1 year of treatment, BMD among patients in Group M significantly increased from baseline by 1.2% and 2.7% at the lumbar spine and trochanter, respectively (P<0.001; and the percentage increase of BMD in Group A was 2

  12. Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line

    Directory of Open Access Journals (Sweden)

    Qi XL

    2012-04-01

    Full Text Available Xiaoli Qi1, Dianrui Zhang2, Xia Xu1, Feifei Feng2, Guijie Ren1, Qianqian Chu1, Qiang Zhang3, Keli Tian11Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, 2Department of Pharmaceutics, College of Pharmacy, Shandong University, Jinan, 3State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, People's Republic of ChinaAbstract: Oridonin, a diterpenoid isolated from Rabdosia rubescencs, has been reported to have antitumor effects. However, low solubility has limited its clinical applications. Preparation of drugs in the form of nanosuspensions is an extensively utilized protocol. In this study, we investigated the anticancer activity of oridonin and oridonin nanosuspension on human pancreatic carcinoma PANC-1 cells. 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide assay was performed to investigate the effect of oridonin on cell growth. Propidium iodide and Hoechst 33342 staining were used to detect morphologic changes. The percentage of apoptosis and cell cycle progression was determined by flow cytometric method staining with propidium iodide. Annexin V-fluorescein isothiocyanate (FITC/PI staining was used to evaluate cell apoptosis by flow cytometry. Caspase-3 activity was measured by spectrophotometry. The apoptotic and cell cycle protein expression were determined by Western blot analysis. Both oridonin and oridonin nanosuspension induced apoptosis and G2/M phase cell cycle arrest, and the latter had a more significant cytotoxic effect. The ratio of Bcl-2/Bax protein expression was decreased and caspase-3 activity was stimulated. The expression of cyclin B1 and p-cdc2 (T161 was suppressed. Our results showed that oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line.Keywords: cyclin B1, cdc2, caspase-3, Bcl-2, Bax

  13. IGF2BP3 as a potential tissue marker for the diagnosis of esophageal high-grade intraepithelial neoplasia

    Directory of Open Access Journals (Sweden)

    Zhang JJ

    2017-08-01

    Full Text Available Jingjing Zhang,1,* Qing Ji,2,* Chunhua Jiao,3,* Lihua Ren,4 Ye Zhao,4 Yanfang Chen,4 Ruihua Shi,4 Yadong Feng4 1State Key Laboratory of Reproductive Medicine, Department of Prenatal Diagnosis, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing, 2Department of Emergency, Jingjiang People’s Hospital, Jingjiang, 3Department of Gastroenterology, First Affiliated Hospital with Nanjing Medical University, 4Department of Gastroenterology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People’s Republic of China *These authors contributed equally to this work Background: The clinical significance of insulin-like growth factor-II mRNA-binding protein-3 (IGF2BP3 in esophageal high-grade intraepithelial neoplasia (HGIN is not clear. This study was designed to characterize the expression of IGF2BP3 in HGIN. Patients and methods: IGF2BP3 expression was evaluated by Western blot analyses in 12 cases and by immunohistochemistry (IHC in 112 cases. The associations between IGF2BP3 expression in HGIN and the clinicopathological parameters were examined. Results: Moderate to strong IGF2BP3 expression was present in HGIN samples. Using IHC, it was found that IGF2BP3 was positive in 68 (60.71% cases. Intense IHC of IGF2BP3 in HGIN was associated with a deeper lesion depth, and the lesion depth was the only predictor of the positive expression of IGF2BP3. Conclusion: Our results suggested that IGF2BP3 may be a supplementary tissue marker for preoperative diagnosis of HGIN. Keywords: esophageal squamous cell carcinoma, precancerous lesion, immunohistochemistry detection, early diagnosis

  14. 實徵研究/大學圖書館館員與使用者對隱私與應用RFID之態度/蘇小鳳 | Librarians’ and Users’ Attitudes Toward User Privacy and the Application of RFID in Academic Libraries/Shiao-Feng Su

    Directory of Open Access Journals (Sweden)

    蘇小鳳 Shiao-Feng Su

    2009-04-01

    Full Text Available 本研究藉由問卷調查及訪談探索大學圖書館館員與使用者對圖書館應用RFID於讀者服務的考量,以瞭解(1使用者對RFID及圖書館運用RFID的認知與態度;(2哪些個人或圖書資訊是使用者重視的隱私;(3使用者希望圖書館以何種方式保護其隱私;以及(4圖書館館員與使用者間對於使用者隱私的相關內容與程度上的認知差異為何。研究結果顯示,大學圖書館員對應用RFID可能造成使用者個人資訊遭蓄意攔截竊取而致影響隱私權已具清楚的認知,並採用精簡資料的方式作為保護策略,然而大多數學生使用者不清楚RFID的資訊傳輸特性。同學表示重視隱私,不希望RFID晶片中儲存太多個人隱私相關的資料,尤其是身分證字號、戶籍地址、財務資料以及聯絡電話等。同學盼望圖書館對保護學生隱私的政策多做說明。本研究結果可供圖書館運用RFID-based系統之參考,降低使用者憂心以及可能對圖書館產生的疑慮,與使用者維持良好關係。Through face to face interviews and a questionnaire survey, the study explores librarians’ and users’ perception of and perspectives on RFID applications and user privacy in academic libraries. The research was directed by the following questions: (1what are the user’s attitudes towards RFID and RFID applications in academic libraries; (2 what personal information and library records are perceived as privacy by the user; (3 how and to what extent would users expect the library to protect their privacy from being invaded by unauthorized RFID readers; and (4 what are the differences in attitudes toward library user privacy between the librarian and user. The study results show that academic librarians understand that data in an RFID tag on books and ID cards could be subject to involuntary interception, which could lead to the invasion of user privacy. They store minimal data in the tag to protect their users. In contrast, the majority of students are unaware of RFID and its security issues. Students value their information privacy. They request that social security number, residential address, financial data, and telephone number be excluded from the RFID tags on books and ID cards. They also expect that the library provides more detailed information about its privacy policy and protection strategies. The librarian’s awareness of the study results may help academic libraries mitigate the risk of user’s doubt about possible privacy invasion and maintain good library-patron relationship.頁次:55-69

  15. GoFFish: Graph-Oriented Framework for Foresight and Insight Using Scalable Heuristics

    Science.gov (United States)

    2015-09-01

    A. Biem, E. Bouillet, H. Feng, A. Ranganathan , A. Riabov, O. Verscheure, H. Koutsopoulos, and C. Moran, “Ibm infos- phere streams for scalable, real...Systems and Software. Elsevier, 2013, vol. 86, no. 1, pp. 2–11. [5] A. Biem, E. Bouillet, H. Feng, A. Ranganathan , A. Riabov, O. Verscheure, H...Feng, A. Ranganathan , A. Riabov, O. Verscheure, H. Koutsopoulos, and C. Moran. Ibm infosphere streams for scalable, real-time, intelligent

  16. Prompt Global Strike: China and the Spear

    Science.gov (United States)

    2014-04-01

    Network Centric Warfare), Feihang Daodan (Winged Missiles Journal), Issue 11, November 2006, pp. 18-21; Ou Nancheng, Feng Shuxing, and Cao Yuhua are...affiliated with China’s Liberation Army Equipment Institute. Ou Nancheng, Feng Shuxing, and Cao Yuhua , “Kuaisu quanqiu daji xitong yu kongtian xinxi...Shuxing, and Cao Yunhua are affiliated with the PLA Armaments Institute. Ou Nancheng, Feng Shuxing, and Cao Yuhua , “Kuaisu quanqiu daji xitong yu

  17. A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation

    Directory of Open Access Journals (Sweden)

    Shi HS

    2012-05-01

    Full Text Available Hua-shan Shi1,* Xiang Gao,1,3,* Dan Li,1,* Qiong-wen Zhang,1 Yong-sheng Wang,2 Yu Zheng,1 Lu-Lu Cai,1 Ren-ming Zhong,2 Ao Rui,1 Zhi-yong Li,1 Hao Zheng,1 Xian-cheng Chen,1 Li-juan Chen,11State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medicine School, Sichuan University, Chengdu, Sichuan, People's Republic of China; 2State Key Laboratory of Biotherapy and Department of Thoracic Oncology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China; 3Deparment of Pathophysiology, College of Preclinical and Forensic Medical Sciences, Sichuan University, Chengdu, People's Republic of China*These authors contributed equally to this workAbstract: Radiation pneumonitis (RP is an important dose-limiting toxicity during thoracic radiotherapy. Previous investigations have shown that curcumin is used for the treatment of inflammatory conditions and cancer, suggesting that curcumin may prevent RP and sensitize cancer cells to irradiation. However, the clinical advancement of curcumin is limited by its poor water solubility and low bioavailability after oral administration. Here, a water-soluble liposomal curcumin system was developed to investigate its prevention and sensitizing effects by an intravenous administration manner in mice models. The results showed that liposomal curcumin inhibited nuclear factor-κB pathway and downregulated inflammatory factors including tumor necrosis factor-α, interleukin (IL-6, IL-8, and transforming growth factor-β induced by thoracic irradiation. Furthermore, the combined treatment with liposomal curcumin and radiotherapy increased intratumoral apoptosis and microvessel responses to irradiation in vivo. The significantly enhanced inhibition of tumor growth also was observed in a murine lung carcinoma (LL/2 model. There were no obvious toxicities observed in mice. The current results indicate that liposomal curcumin can effectively

  18. Tumor deposit is a poor prognostic indicator in patients who underwent simultaneous resection for synchronous colorectal liver metastases

    Directory of Open Access Journals (Sweden)

    Lin Q

    2015-01-01

    Full Text Available Qi Lin,# Ye Wei,# Li Ren,# Yunshi Zhong,# Chunzhi Qin, Peng Zheng, Pingping Xu, Dexiang Zhu, Meiling Ji, Jianmin XuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China#These authors contributed equally to this workBackground: Tumor deposits are one of the important influencing factors among the different editions of Tumor, Node, Metastasis classification. Incidence and prognosis of tumor deposits in stage I, II, and III colorectal cancer patients has been explored. The aim of this study was to determine the prognostic value of tumor deposits in stage IV colorectal cancer patients who underwent simultaneous resection for synchronous colorectal liver metastases (SCRLM.Methods: Clinicopathological and outcome data of 146 consecutive SCRLM patients who underwent simultaneous R0 resection between July 2003 and July 2013 were collected from our prospectively established SCRLM database. The prognostic value of tumor deposits was evaluated by Kaplan–Meier and Cox regression analysis.Results: Tumor deposits were detected in 41.8% (61/146 of these SCRLM patients. Tumor deposits were significantly correlated with lymph node metastasis and nerve invasion of the primary tumors (P=0.002, P=0.041; respectively. The Kaplan–Meier survival analysis revealed that the overall survival (OS and disease-free survival (DFS of SCRLM patients with tumor deposits were significantly poorer than those with no tumor deposits (P=0.039, P=0.001; respectively. And with multivariate analysis, we found that positive tumor deposits were significantly associated with shorter DFS independent of lymph node status (P=0.002. Subgroup analysis found that of the 57 SCRLM patients with negative lymph node status, the OS and DFS of patients with positive tumor deposits were significantly shorter than those with negative tumor deposits (P=0.002 and P=0.031, respectively. Of the 89 patients with positive lymph node status, the OS of

  19. The hydroxypropyl–β-cyclodextrin complexation of toltrazuril for enhancing bioavailability

    Directory of Open Access Journals (Sweden)

    Zhang L

    2018-03-01

    Full Text Available Li Zhang,1,2,* Mengxi Liu,1,* Chaocheng Lu,1 Dandan Ren,1 Guoqing Fan,1 Chang Liu,1 Mengjiao Liu,1 Gang Shu,1 Guangneng Peng,1 Zhixiang Yuan,1 Zhijun Zhong,1 Wei Zhang,1 Hualin Fu1 1Department of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China; 2Institute of Traditional Chinese Medicine Pharmacology and Toxicology, Sichuan Academy of Chinese Medicine Sciences, Chengdu, Sichuan, China *These authors contributed equally to this work Introduction: Toltrazuril (Tol is used to prevent and combat coccidiosis. However, its low aqueous solubility and poor oral bioavailability limit clinical application. Methods: To overcome the shortcomings, toltrazuril–hydroxypropyl–β-cyclodextrin inclusion complex (Tol-HP-β-CD was prepared and characterized. The comparative plasma disposition kinetics of Tol was analyzed after a single orally administered dose of 10 mg/kg Tol or Tol-HP-β-CD in rabbits. Solution-stirring method was selected to prepare the inclusion complex. Complex formation was characterized by thin-layer chromatography, Fourier transform infrared spectrophotometry, and 1H nuclear magnetic resonance spectroscopy. In plasma profile, plasma samples were collected between 1 and 10 days following administration. Plasma Tol concentrations were determined by high-performance liquid chromatography. Results: In rabbit plasma, the time to peak concentration (Tmax of Tol-HP-β-CD was shorter than that of Tol (12 h vs 24 h. Cmax (19.92±1.02 µg/mL and area under the concentration–time curve (AUC0-∞, 1,176.86±70.26 mg/L h of the Tol-HP-β-CD group significantly increased (p<0.01 than those of the Tol group (Cmax, 8.02±1.04 µg/mL; AUC0-∞, 514.03±66.65 mg/L h. Conclusion: It can be concluded that the Tol-HP-β-CD increased the aqueous solubility and enhanced the oral bioavailability in rabbits. Complexation with HP-β-CD is a feasible way to prepare a rapidly absorbed and more bioavailable Tol

  20. Increased risk of severe infections in cancer patients treated with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Ma Q

    2015-08-01

    Full Text Available Qing Ma, Li-Yan Gu, Yao-Yao Ren, Li-Li Zeng, Ting Gong, Dian-Sheng Zhong Department of Oncology, The General Hospital of Tianjin Medical University, Tianjin, People’s Republic of China Background: Vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs have been widely used in a variety of solid malignancies. Concerns have arisen regarding the risk of severe infections (≥grade 3 with use of these drugs, but the contribution of VEGFR-TKIs to infections is still unknown.Methods: The databases of PubMed and abstracts presented at oncology conferences’ proceedings were searched for relevant studies from January 2000 to December 2014. Summary incidences, Peto odds ratio (Peto OR, and 95% confidence intervals (CIs were calculated by using either random-effects or fixed-effects models according to the heterogeneity of included studies.Results: A total of 16,488 patients from 27 randomized controlled trials were included. The risk of developing severe (Peto OR 1.69, 95% CI: 1.45–1.96, P<0.001 and fatal infections (Peto OR 1.78, 95% CI: 1.13–2.81, P=0.013 was significantly increased in patients treated with VEGFR-TKIs when compared to controls. Exploratory subgroup analysis showed no effect of tumor types, phase of trials, or agent used on the Peto OR of severe infections. When stratified according to specific infectious events, the risks of high-grade febrile neutropenia, pneumonia, fever, and sepsis were increased compared with controls, with Peto ORs of 1.57 (95% CI: 1.30–1.88, P<0.001, 1.79 (95% CI: 1.29–2.49, P<0.001, 5.35 (95% CI: 1.47–19.51, P=0.011, and 3.68 (95% CI: 1.51–8.99, P=0.004, respectively. Additionally, VEGFR-TKIs significantly increased the risk of fatal sepsis (OR 3.66, 95% CI: 1.47–9.13, P=0.005 but not fatal pneumonia (OR 1.34, 95% CI: 0.80–2.25, P=0.26.Conclusion: The use of VEGFR-TKIs significantly increases the risk of developing severe and fatal infectious events in cancer

  1. The outcomes of intra-aortic balloon pump usage in patients with acute myocardial infarction: a comprehensive meta-analysis of 33 clinical trials and 18,889 patients

    Directory of Open Access Journals (Sweden)

    Fan ZG

    2016-03-01

    Full Text Available Zhong-Guo Fan,1,* Xiao-Fei Gao,1,2,* Li-Wen Chen,1 Xiao-Bo Li,1,2 Ming-Xue Shao,1,2 Qian Ji,1 Hao Zhu,1 Yi-Zhi Ren,1 Shao-Liang Chen,1,2 Nai-Liang Tian1,2 1Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 2Department of Cardiology, Nanjing Heart Center, Nanjing, People’s Republic of China *These authors contributed equally to this work Background: The effects of intra-aortic balloon pump (IABP usage in patients with acute myocardial infarction remain controversial. This study sought to evaluate the outcomes of IABP usage in these patients.Methods: Medline, EMBASE, and other internet sources were searched for relevant clinical trials. The primary efficacy endpoints (in-hospital, midterm, and long-term mortality and secondary endpoints (reinfarction, recurrent ischemia, and new heart failure in the hospital as well as safety endpoints (severe bleeding requiring blood transfusion and stroke in-hospital were subsequently analyzed.Results: Thirty-three clinical trials involving 18,889 patients were identified. The risk of long-term mortality in patients suffering from acute myocardial infarction was significantly decreased following IABP use (odds ratio [OR] 0.66, 95% confidence interval [CI]: 0.48–0.91, P=0.010. Both in-hospital and midterm mortality did not differ significantly between the IABP use group and no IABP use group (in-hospital: OR 0.87, 95% CI: 0.59–1.28, P=0.479; midterm: OR 1.12, 95% CI: 0.53–2.38, P=0.768. IABP insertion was not associated with the risk reduction of reinfarction, recurrent ischemia, or new heart failure. However, IABP use increased the risk of severe bleeding requiring blood transfusion (OR 2.05, 95% CI: 1.29–3.25, P=0.002 and stroke (OR 1.71, 95% CI: 1.04–2.82, P=0.035. In the thrombolytic therapy and cardiogenic shock subgroups, reduced mortality rates following IABP use were observed.Conclusion: IABP insertion is associated with feasible benefits with respect to long

  2. Correction: Experimental and theoretical studies of nanofluid thermal conductivity enhancement: a review

    Directory of Open Access Journals (Sweden)

    Kleinstreuer Clement

    2011-01-01

    Full Text Available Abstract Correction to Kleinstreuer C, Feng Y: Experimental and theoretical studies of nanofluid thermal conductivity enhancement: a review. Nanoscale Research Letters 2011, 6:229.

  3. Reduktion av slöseri inom den spanska ölindustrin : – en studie av åtgärder och metoder i spåren av krisen

    OpenAIRE

    Carlström, Carl

    2014-01-01

    Den rådande eurokrisen har påverkat det spanska samhället och den spanska ölindustrin negativt. Industrin står inför utmaningar vad gäller minskad försäljning och förändrade kundpreferenser. I tider då intäkterna och försäljningen minskar finns det många sätt att öka sina marginaler. Ett av detta sätt är att börja arbeta med resurseffektivitet och att se till att slöseriet av de resurser man har minskar. De frågor studien besvarar är hur bryggeriindustrin i Spanien har arbetat för att minska ...

  4. Effectiveness of geriatric rehabilitation among patients with secondary diagnosis dementia [Effektivität der ambulanten und stationären geriatrischen Rehabilitation bei Patienten mit der Nebendiagnose Demenz

    Directory of Open Access Journals (Sweden)

    Korczak, Dieter

    2012-09-01

    Full Text Available [english] Often geriatric patients with secondary diagnosis dementia do not receive a rehabilitation treatment, although it is an obligatory service offered by the statutory health insurance. Scientists have examined the benefit of relevant measures for patients who are slightly or moderately affected with dementia. Thus, also these patients would profit by a rehabilitation.[german] Geriatrische Patienten mit Nebendiagnose Demenz erhalten oft keine Rehabilitation, obwohl diese zu den Pflichtleistungen der gesetzlichen Krankenkasse gehört. Wissenschaftler haben untersucht, ob und wenn ja, welchen Nutzen entsprechende Maßnahmen für leicht bis moderat demenzkranke Patienten haben. Demnach profitieren durchaus auch diese Patienten von einer Rehabilitation.

  5. Ülema vastutus rahvusvahelises õiguses ICTY ja ICTR kohtupraktika näidetel : [magistritöö] / Katrin Värte ; Tartu Ülikool, õigusteaduskond ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Värte, Katrin

    2010-01-01

    Ülema vastutuse olemusest ja selle elementidest, tsiviilülemate vastutusest, otsesest vastutusest versus ülema vastutusest. Endise Jugoslaavia Rahvusvahelise Kriminaaltribunal = ICTY. Rwanda Rahvusvaheline Kriminaaltribunal = ICTR

  6. Maailma dopinguvastane koodeks : selle vastavus inimõiguste ja õiguse üldpõhimõtetele : [bakalaureusetöö] / Jane Kalda ; Tartu Ülikool, õigusteaduskond ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Kalda, Jane

    2010-01-01

    Maailma Antidopingu Agentuurist ja Maailma antidopingu koodeksist, inimõigustest ja õiguse üldiste põhimõtete rollist dopinguvaidlustes, koodeksi artiklite vastavusest inimõiguste ja õiguse üldpõhimõtetele

  7. Štrasburská hus v Kodani: Náčrt pojmu irónie u Sørena Kierkegaarda (Strasbourg goose in Copenhagen: An outline to the concept of irony in Søren Kierkegaard’s work

    Directory of Open Access Journals (Sweden)

    Česlav Peter Šajda

    2006-09-01

    Full Text Available The author of this text makes clear the circumstances of origin, structure, and content of Kierkegaard´ s master dissertation thesis. He analyses understanding of irony, his relation to Socrates and irony in totality of Kierkegaard’s understanding. The conclusion of this text points to irony of Kierkegaard’s destiny.

  8. Human animal bond within the context of dementia - Möglichkeiten tiergestützter Intervention für das psychosoziale Wohlbefinden und die Lebensqualität alter und dementer Menschen in stationären Einrichtungen

    OpenAIRE

    Beckmann, Antje

    2014-01-01

    It has already been established that animals have various constitutional effects on humans and influence quality of life and well-being in various ways (see Nestmann 2005). For a lot of people in all stages of their life, pets are important sources of support. They are able to contribute to our health as well as to buffer stress and illness. Especially elderly and frail people take profit from the human animal bond. Pets may be seen as important agents in support and therapy of people wit...

  9. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study.

    Science.gov (United States)

    Francis, Nick A; Ridd, Matthew J; Thomas-Jones, Emma; Shepherd, Victoria; Butler, Christopher C; Hood, Kerenza; Huang, Chao; Addison, Katy; Longo, Mirella; Marwick, Charis; Wootton, Mandy; Howe, Robin; Roberts, Amanda; Haq, Mohammed Inaam-ul; Madhok, Vishnu; Sullivan, Frank

    2016-03-01

    Secondary skin infection is common during eczema exacerbations and many children are treated with antibiotics when this is suspected, although there is little high-quality evidence to justify this practice. To determine the clinical effectiveness of oral and topical antibiotics, in addition to standard treatment with emollients and topical corticosteroids, in children with clinically infected eczema. Multicentre randomised, double-blind, placebo-controlled trial. General practices and dermatology clinics in England, Wales and Scotland. Children (aged 3 months to children (36 to oral antibiotic, 37 to topical antibiotic and 40 to placebo), which was fewer than our revised target sample size of 282. A total of 103 (92.0%) children had one or more clinical features suggestive of infection and 78 (69.6%) children had Staphylococcus aureus cultured from a skin swab. Oral and topical antibiotics resulted in a 1.52 [95% confidence interval (CI) -1.35 to 4.40] and 1.49 (95% CI -1.55 to 4.53) increase (worse subjective severity) in POEM score at 2 weeks, relative to placebo and controlling for baseline POEM score. Eczema Area and Severity Index (objective severity) scores were also higher (worse) in the intervention groups, at 0.20 (95% CI -0.12 to 0.52) and 0.42 (95% CI 0.09 to 0.75) for oral and topical antibiotics, respectively, at 2 weeks. Analyses of impact on the family, quality of life, daily symptom scores, and longer-term outcomes were all consistent with the finding of no or limited difference and a trend towards worse outcomes in the intervention groups. Sensitivity analyses, including adjusting for compliance and imputation for missing data, were consistent with the main findings. Our data suggest that oral and topical antibiotics have no effect, or a harmful effect, on subjective eczema severity in children with clinically infected eczema in the community. The CIs around our estimates exclude a meaningful beneficial effect (published minimal clinically important difference for POEM is 3.4). Although most patients in this trial had features suggestive of infection and S. aureus on their skin, participants primarily had mild-moderate eczema and those with signs of more severe infection were often excluded. Clinicians should consider avoiding oral and topical antibiotic use in children with suspected infected eczema in the community who do not have signs of 'severe infection'. Further research should seek to understand how best to encourage the use of topical steroids and limit use of antibiotics in those with eczema flares without signs of severe infection, as well as developing tools to better phenotype eczema flares, in order to better define a population that may benefit from antibiotic treatment. European Union Drug Regulating Authorities Clinical Trials (EudraCT) number 2011-003591-37 and Current Controlled Trials ISRCTN96705420. The National Institute for Health Research Health Technology Assessment programme.

  10. Rahvusvahelise terrorismi rahastamise tõkestamise õiguslikud võimalused ja probleemid : [magistritöö] / Deivid Uibo ; Tartu Ülikool, õigusteaduskond Tallinnas ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Uibo, Deivid, 1987-

    2013-01-01

    Rahvusvahelise terrorismi rahastamise vastase võitluse olemusest, rahvusvahelise õiguse meetmetest ja nende tõhususest terrorismi rahastamise tõkestamisel, õiguslikest probleemidestedasiarendustest

  11. La crítica de la mediación hegeliana en el segundo volumen de Enten-Eller (O lo uno o lo otro de Søren Kierkegaard. ¿Una crítica social?

    Directory of Open Access Journals (Sweden)

    EDUARDO ASSALONE

    2014-06-01

    Full Text Available En el presente trabajo se aborda la crítica a la doctrina hegeliana de la mediación (Vermittlung que Kierkegaard desarrolla en el segundo volumen de Enten-Eller (O lo uno o lo otro. El trabajo comienza con un análisis del tipo de oposición que Kierkegaard no está dispuesto a relativizar por vía del recurso a la mediación dialéctica. Para ello se aplican los aportes realizados por Shannon Nason para la comprensión de los opuestos relativos en Hegel y en Kierkegaard. Luego se señala el lugar que le confiere este último filósofo al concepto de mediación en su posición propia, a saber, dentro de la “esfera del pensamiento”. Posteriormente se aborda la crítica de Theodor W. Adorno al intento kierkegaardiano de desarrollar una “dialéctica sin mediación”. En el último apartado se evalúa, en conjunto, la crítica y limitación del concepto de mediación realizadas por Kierkegaard, así como las objeciones elevadas por Adorno contra las mismas. Asimismo, se presentan algunas reflexiones sobre la crítica de la mediación por parte de Kierkegaard y del joven Marx como expresión de una crítica social que permanece implícita en el primero y se muestra explícitamente en el segundo.

  12. Schulbücher und Lektüren in der Unterrichtspraxis an böhmischen und mährischen Lateinschulen des 16. und frühen 17. Jahrhunderts

    Czech Academy of Sciences Publication Activity Database

    Holý, Martin

    2012-01-01

    Roč. 15, Sonderheft 17 (2012), s. 105-119 ISSN 1434-663X Institutional support: RVO:67985963 Keywords : Bohemian Lands * Early Modern Period * text-books Subject RIV: AB - History Impact factor: 0.434, year: 2012

  13. Sarah Dellmann: Widerspenstige Körper. Körper, Kino, Sprache und Subversion in Tod Brownings FREAKS und Filmen mit Lon Chaney. Marburg: Schüren Verlag 2009.

    Directory of Open Access Journals (Sweden)

    Fabian Tietke

    2010-11-01

    Full Text Available Im vorliegenden Band werden Filme des in den 1920er und 1930er Jahren sehr erfolgreichen Regisseurs Tod Browning analysiert, insbesondere sein heute bekanntestes Werk Freaks. Mithilfe historischer Kontextualisierungen und eines filmwissenschaftlichen Instrumentariums untersucht Dellmann die These, dass sich in diesem Werk Spuren eines heute verloren gegangenen Körperverständnisses finden lassen – vor allem andere Repräsentationen von Behinderung und behinderten männlichen Körpern.The present anthology analyzes several movies of the director Tod Browning (who was very successful in the 1920s and 1930s, particularly the movie Freaks which, today, is his most well-known work. Using historical contextualizations and a Film Studies background, Dellmann explores the thesis that this work shows traces of an understanding of the body that today no longer exist, above all the representation of disabilities and disabled male bodies.

  14. Binary vapour—liquid equilibria of methanol with sulfolane. Tetraethylene glycol dimethyl ether and 18-crown-6 = Phasengleichgewichte in binären systemen von Methanol mit Sulfolan, Tetraethylenglycoldimethylether und 18-krone-6 Kronenether

    NARCIS (Netherlands)

    Kuczynski, M.; 't Hart, W.; Westerterp, K.R.

    1986-01-01

    The activity coefficients of methanol in sulfolane, tetraethylene glycol dimethyl ether (TEGDME) and 18-crown-6 under conditions of equilibrium have been determined in the temperature range 423–503 K and in the pressure range 0.28–3.5 MPa. A minimum in the activity coefficient was found for the

  15. Diplomaatilise immuniteedi erandid tsiviilõiguslikes küsimustes : [bakalaureusetöö] / Argo Reiljan ; Tartu Ülikooli Õigusinstituut ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Reiljan, Argo

    2006-01-01

    Diplomaatilised privileegid ja immuniteedid ning nende erinevad teooriad, diplomaatilise esinduse liikme kriminaal-, tsiviil- ja halduskohtulik immuniteet vastuvõtjariigi kohtulikust jurisdiktsioonist, tsiviilkohtuliku immuniteedi erandid, erandite korral tehtud kohtuotsuste täideviimine

  16. Att reproducera en människa med hjälp av en annan människa - en affektiv analys av vård- och hemarbete i den privata sfären

    OpenAIRE

    Wide, Elisabetg

    2017-01-01

    This master’s thesis examines migrant care and domestic work in private households in Finland as affective labour. This particular spectrum of reproduction is approached from the perspectives of migrant workers and employers. Firstly, the thesis analyses how workers express affective and precarious aspects of their labour. Secondly, the thesis demonstrates how the demand for privately employed care and domestic work is produced, and discusses what this bought service consists of. Finally, eve...

  17. Att drabbas av cancer i tonåren : En kvantitativ studie om hälsorelaterad livskvalitet två till fyra år efter diagnos

    OpenAIRE

    Hiding, Markus; Lavemark, Niklas

    2010-01-01

    Syfte Studiens syfte var att undersöka: självskattad hälsorelaterad livskvalitet hos tonåringar som drabbats av cancer två år (T5), tre år (T6) och fyra år (T7) efter diagnos, samt att jämföra deras skattningar med en referensgrupp randomiserad från befolkningen.   Metod Tonåringarna med cancer besvarade SF-36 2 år (N=38), 3 år (N=42) samt 4 år (N=39) efter diagnos. En referensgrupp (N=300) randomiserad av Statistiska centralbyrån (SCB) besvarade samma formulär vid ett tillfälle. Samtlig data...

  18. Diplomaatiline asüül : olemus ja andmise õiguspärasus : [bakalaureusetöö] / Karel Virks ; Tartu Ülikooli Õigusinstituut ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Virks, Karel

    2007-01-01

    Asüüli ja asüüliõiguse terminoloogia ja olemus, asüül diplomaatilises esinduses ja diplomaatilise asüüli printsiibid, õigus diplomaatsilisele asüülile, riikide seisukohad diplomaatilise asüüli kodifitseerimiseks

  19. Jaderná bezpečnost fúzních elektráren a jejich vliv na životní prostředí.

    Czech Academy of Sciences Publication Activity Database

    Entler, Slavomír; Dostál, V.

    2017-01-01

    Roč. 25, 9-10 (2017), s. 262-268 ISSN 1210-7085 Grant - others:AV ČR(CZ) StrategieAV21/2 Program:StrategieAV Institutional support: RVO:61389021 Keywords : design * reactor safety * thermonuclear fuel s * thermonuclear reactions * thermonuclear reactor materials * thermonuclear reactors * tokamak devices Subject RIV: JF - Nuclear Energetics OBOR OECD: Nuclear related engineering

  20. Aplikace metod vizualizace v prostorovém plánování: příklad výstavby větrných elektráren

    Czech Academy of Sciences Publication Activity Database

    Nováková, Eva; Frantál, Bohumil

    2009-01-01

    Roč. 55, č. 5 (2009), s. 1-3 ISSN 0016-7096 R&D Projects: GA AV ČR(CZ) KJB700860801 Institutional research plan: CEZ:AV0Z30860518 Keywords : visualization * mental mapping * wind turbines * visibility analyses * GIS * spatial planning Subject RIV: DE - Earth Magnetism, Geodesy, Geography

  1. Kvinnor i olympiaden. En jämförande studie av kvinnors representation och framställning i media under OS-åren 1996 och 2016

    OpenAIRE

    Källman, Marie; Fellman, Elin

    2017-01-01

    Abstract Women in the olympics - A quantitative and qualitative analysis of the representation and portayal of female athletes in the olympics The purpose of the study was to examine how often female athletes occur in swedish sports media and how they are portrayed, in comparison to male athletes. The years studied was 1996 and 2016. Since the female participants increased over those twenty years it was interesting to see if the media followed that development. The study is based on earlier r...

  2. Präferenzen, Wohlergehen und Rationalität – Zu den begrifflichen Grundlagen des libertären Paternalismus und ihren Konsequenzen für seine Legitimierbarkeit

    Directory of Open Access Journals (Sweden)

    Klonschinski Andrea

    2016-07-01

    Full Text Available Der libertäre Paternalismus (LP genießt in Politik, Wissenschaft und Öffentlichkeit eine große Popularität, die er insbesondere zwei Merkmalen verdankt: Erstens stützt sich der LP auf verhaltensökonomische Ergebnisse, die zeigen, dass individuelle Entscheidungen oft nicht der neoklassischen Rationalitätskonzeption entsprechen, sodass Individuen durch sogenanntes Nudging zu besseren, ihren wahren Präferenzen entsprechenden Entscheidungen verholfen werden könne. Zweites ist damit der Anspruch verbunden, das Wohlergehen der Individuen, wie sie selbst es verstehen, zu erhöhen. Dieser Beitrag zeigt anhand einer dogmengeschichtlichen Analyse der zentralen, dem LP zugrunde liegenden Begriffe Präferenz, Nutzen, Rationalität und Wohlergehen, dass der LP diesen Anspruch nicht einlösen kann. Eine detaillierte begriffliche Analyse ist deshalb geboten, weil diese Konzepte in der Ökonomik immer wieder für Missverständnisse sorgen. Eine theoriegeschichtlich informierte Untersuchung wiederum ist notwendig, da diese Konfusion insbesondere auf der Tatsache beruht, dass der Gehalt dieser Begriffe sich im Laufe der Zeit gravierend verändert hat und sich die verschiedenen Bedeutungen heute z. T. wechselseitig überlagern.

  3. Effects of Combined Endothelin A Receptor and Renin-Angiotensin System Blockade on the Course of End-Organ Damage in 5/6 Nephrectomized Ren-2 Hypertensive Rats

    Czech Academy of Sciences Publication Activity Database

    Vaněčková, Ivana; Kujal, P.; Husková, Z.; Vaňourková, Z.; Vernerová, Z.; Čertíková; Chábová, V.; Škaroupková, P.; Kramer, H. J.; Tesař, V.; Červenka, L.

    2012-01-01

    Roč. 35, č. 5 (2012), s. 382-392 ISSN 1420-4096 Institutional research plan: CEZ:AV0Z50110509 Keywords : 5/6 nephrectomy * Endothelin receptor type A * AT1 receptor blocker * end-organ damage * hypertension Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 1.596, year: 2012

  4. Renin-angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats

    Czech Academy of Sciences Publication Activity Database

    Sedláková, L.; Čertíková; Chábová, V.; Doleželová, Š.; Škaroupková, P.; Kopkan, L.; Husková, Z.; Červenková, L.; Kikerlová, S.; Vaněčková, Ivana; Sadowski, J.; Kompanowska; Jezierska, E.; Kujal, P.; Kramer, H. J.; Červenka, L.

    2017-01-01

    Roč. 39, č. 2 (2017), s. 183-195 ISSN 1064-1963 Institutional support: RVO:67985823 Keywords : chronic kidney disease * endothelin system * hypertension * renin–angiotensin system * 5/6 nephrectomy Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery OBOR OECD: Cardiac and Cardiovascular systems Impact factor: 1.162, year: 2016

  5. „... das Unendliche im Endlichen gebären ...“ “To Bring Forth the Infinite in the Finite”: the Process of Signification in Creuzer’s Theory of the Symbol

    Directory of Open Access Journals (Sweden)

    Susanne Gödde

    2010-12-01

    Full Text Available La contribution analyse les procédés de signification spécifiques de ce qui dans la Symbolique de Creuzer est appelé « mythe » et « symbole ». On peut en distinguer trois : 1. La signification d’un mythe ou d’une figure mythologique se reconstitue en affirmant une ressemblance interreligieuse ou linguistique (notamment par recours à l’étymologie de sorte que la « vraie » doctrine religieuse est retrouvée dans ces relations établies entre les mots et les noms. 2. La signification se reconstitue par l’indexicalité d’une image divine (essentiellement aniconique, l’image cultuelle du phallus en tant que lettre d’une langue naturelle y acquérant une signification sémiotique particulière. 3. La signification se reconstitue par une disparité de forme et contenu. Dans ce cas, le symbole qui risque de faire éclater sa forme contient une composante extatique. Contrairement au postulat classique de l’accompli et d’un tout bien proportionné, cette disparité présente des aspects d’une esthétique du laid. Ces trois procédés proviennent d’une herméneutique romantique et peuvent être considérés comme anti-classiques.The following contribution investigates the specific means of signification that Creuzer articulates for the categories ‘symbol’ and ‘myth’ in his Symbolik und Mythologie der alten Völker (Symbolism and Mythology of the Ancient Peoples. Three processes of signification can be distinguished: 1. the meaning of a myth or mythical figure is constituted by  postulating inter-religious relations, often with recourse to etymological or similar linguistic relations; and a previous truth or dogmatic system is inferred to lie ‘behind’ the narrative and its linguistic interrelations. In these cases, Creuzer locates the authentic religious meaning within those relations. 2. Meaning is constituted through the indexicality of a (primarily aniconic image of a god, whereby the cult-image of a phallus (which, according to Creuzer, represents the letter of a natural language emerges as a privileged signifier. 3. Meaning is constituted by an incongruence of form and content. In this case, the symbol, threatening to explode its form, contains an ecstatic component. In contrast to the classicist ideal of a self-contained and well-proportioned whole, this incongruence gestures towards an aesthetic of ugliness. All three processes can be understood as anti-classical, bound up in a romantic hermeneutic.Der folgende Beitrag möchte nach den spezifischen Bedeutungsweisen von Mythos und Symbol in Creuzers Symbolik und Mythologie der alten Völker fragen. Drei Verfahren des Bedeutens lassen sich ausmachen: 1. Die Bedeutung eines Mythos oder einer mythologischen Figur konstituiert sich über das Konstrukt einer interreligiösen Verwandtschaft oder Sprachähnlichkeit bzw. Etymologie, so daß in den postulierten Bezügen der Wörter und Namen die eigentliche religiöse Lehre ausgemacht wird. 2. Die Bedeutung konstituiert sich über die Indexikalität eines (dann vornehmlich anikonischen Götterbildes, wobei in dieser Variante das Kultbild des Phallos, das als Buchstabe einer Natursprache aufgefaßt wird, besondere zeichentheoretische Signifikanz erhält. 3. Die Bedeutung konstituiert sich durch die Inkongruenz von Form und Inhalt. In diesem Fall erfährt das Symbol, das seine Form zu sprengen droht, eine ekstatische Komponente. Die Inkongruenz weist – im Gegensatz zum Postulat des In-sich-Vollendeten und wohlproportionierten Ganzen – Momente einer Ästhetik des Häßlichen auf. Alle drei Verfahren können als anti-klassizistisch und einer romantischen Hermeneutik verpflichtet betrachtet werden.

  6. Factores de riesgo asociados a hábitos bucales deformantes en niños de 5 a 11 años. Policlínica “René Vallejo Ortiz”: Manzanillo. 2004 - 2005

    OpenAIRE

    Reyes Romagosa, Daniel Enrique; Rosales Rosales, Katiuska; Roselló Salcedo, Olga; García Arias, Dasha María

    2007-01-01

    RESUMEN Se  realizó un estudio de tipo caso control  de niños afectados por hábitos bucales  deformantes de la  Policlínica III “Rene Vallejo Ortiz”  de  Manzanillo en el periodo comprendido entre abril  del 2004 y abril  del 2005, con el objetivo de identificar los factores de riesgo asociados a esos hábitos bucales deformantes. Del total de niños de 5 a 11 años del área se seleccionaron 180 niños, 60 niños con hábitos bucales deformantes  que se examinaron en consulta y se les realizó una e...

  7. Entre a recriação e a renúncia, o ato de deixar falar: breve abordagem sobre produtividade poética brasileira e polifonia a partir de Chico Alvim e Carlos Nejar

    Directory of Open Access Journals (Sweden)

    Cinthia Maritz dos Santos Ferraz Machado

    2016-08-01

    Full Text Available Este artigo propõe uma abordagem acerca da produtividade literária e da polifonia na poética brasileira contemporânea a partir de autores como Chico Alvim e Carlos Nejar. Pretendemos demonstrar que processos de criação configuram as obras destes poetas que têm em comum a característica do ato de deixar falar: de conferir ou imprimir vozes às suas criações num processo de ânima. Chico Alvim e Carlos Nejar manejam o discurso fora da ordenação ou da hegemonia. Inscrevem-no na expressão da pluralidade por meio de um movimento ou jogo dinâmico; do processo contínuo e não de um sistema operante e determinante. Em seus poemas estão inscritas a dramatis personae, responsável pelo trânsito entre o olhar e o deixar falar, em direção ao leitor.

  8. Looduskeskkonna kahjustamise sõjakuritegu Rooma statuudi artikkel 8(2)(b)(iv) mõistes : [bakalaureusetöö] / Kadrin Toonekurg ; Tartu Ülikool, õigusteaduskond ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Toonekurg, Kadrin

    2010-01-01

    Keskkonnakaitsest relvakonfliktide käigus, rahvusvahelistest kokkulepetest. Kahju piiritlemisest, elementidest, ulatusest (Lahesõja näitel).Proportsionaalsusest, selle hindamisest (Kosovo konflikti näitel)

  9. SAKARYA İLİNDE 17 AGUSTOS 1999 DEPREMiNDE HASAR GÖREN Y APlLAR ÜZERİNE BİR ARAŞTIRMA

    Directory of Open Access Journals (Sweden)

    Fatih İLÇİ

    2003-08-01

    Full Text Available Doğal afetler aras ı nda , yapılara en büyük zararı depremler venniş ti r. Bunun için, her an deprem olacakmış gibi h az ı r olun ınalıdır. Ya p ı yapma fikri( daha y e ni ohışına aşan1asında i ken , inşaat sektörü ile ilgili tünı meslek grupları s ürekli bir ko o rd in asy on n ç i nde çalışnıalıdır. Bu ko ordi ne l i çalışnıa neticesinde; 17 Ağustos 1999 d epremini n türrı ol ums uz sonuçlan iyi bir şekilde anl aşılıp, dcpreme karşı nas ı l dayanıklı yapı yapabili rim. Fikri benimsenmelidir.

  10. THE MAN HAD LINGUISTICS LIKED: PROF. DR. DOĞAN AKSAN DİL BİLİMİNİ SEVDİREN ADAM: PROF. DR. DOĞAN AKSAN (1929-2010

    Directory of Open Access Journals (Sweden)

    Ahmet Turan SİNAN

    2010-10-01

    Full Text Available Who is the linguistics studies’ the one of innovators in Turkey, Prof. Dr. Doğan Aksan is very important scientist who fall in love with Turkish, reweal the richness and power of expression of our mother tangue. He displays a lot of European turcologits’ delussions as A. von Gabain, R. Giraud, J. Kramsky for Turkish with his studies. Aksan, who writes a lot of studies for shabbiness, semantic features, expression, flexibility of Turkish, Turkish education, takes place between founders of linguistic in Turkey. He displays the big love to Turkish by serving to Turkish in the light of the methods and techniques of universal linguistic. Prof. Dr. Doğan Aksan will be remember always as a very important scientist and the man had linguistics liked. Türkiye’deki dil bilim çalışmalarının öncülerinden olan Prof. Dr. Doğan Aksan; Türkçeye gönül vermiş, anlam bilim çalışmaları ile ana dilimizin zenginliğini ve anlatım gücünü gözler önüne seren çok önemli bir bilim adamıdır. Bu çalışmaları ile A. von Gabain, R. Giraud, J. Kramsky gibi birçok Avrupalı Türkologun Türkçeye yönelik yanılgılarını da ortaya koymuştur. Türkçenin eskiliğine, anlamsal özelliklerine, anlatım gücü ve esnekliğine, Türkçe öğretimine yönelik birçok esere imza atan Aksan, Türkiye’de dil bilimin kurucuları arasında yer alır. Türkçeye olan büyük sevgisini evrensel dil bilimin yöntem ve teknikleri ışığında hizmet ederek göstermiştir. Prof. Dr. Doğan Aksan, çok önemli bir bilim adamı ve her şeyden önce dil bilimi sevdiren kişi olarak daima hatırlanacaktır.

  11. Venemaa Födratsiooni riigikaitseseaduse muudatuste õiguspärasus rahvusvahelise õiguse kontekstis : [bakalaureusetöö] / Ranno Pajuri ; Tartu Ülikool, õigusteaduskond ; juhendaja: René Värk

    Index Scriptorium Estoniae

    Pajuri, Ranno

    2010-01-01

    Venemaa riigikaitseseaduse muudatuste põhjustest, kontekstist, eesmärkidest ja sisust. Kodanike kaitseks relvastatud jõu kasutamise instituudist rahvusvahelises õiguses. Kollektiivse enesekaitse instituudist Venemaa riigikaitseseaduses ja rahvusvahelises õiguses

  12. African Journal of Biotechnology - Vol 11, No 70 (2012)

    African Journals Online (AJOL)

    Embryogenesis and plant regeneration from unpollinated ovaries of Amorphophallus konjac · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Lingling Zhao, Jinping Wu, Ying Diao, Zhongli Hu, 13472-13476 ...

  13. Comparative immunomudulating effects of five orally administrated ...

    African Journals Online (AJOL)

    plzfg

    inflammatory cytokine ..... expression and induction of manganese-superoxide dismutase in the adenohypophysis. Histochem. ... Sugino N, Hirosawa-Takamori M, Zhong L, Telleria CM, Shiota K & Gibori G (1998) Hormonal regulation of.

  14. Research Article Special Issue

    African Journals Online (AJOL)

    2017-09-10

    Sep 10, 2017 ... include revolvers, self-loading pistols, rifles, carbines, assault rifles, submachine .... This section provides related theory on spring that was modelled in the .... Zhong-Xian L. Development and experimental verification of a.

  15. A kinetic model for citric acid productionfrom apple pomac by ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-10-06

    Oct 6, 2008 ... system. The model can provide useful suggestions for the analysis, design and operation of a fermenter. Fer- mentation models are normally ... Structured model seems complicated for normal use. (Jian-Zhong et al., 2002).

  16. The Chinese Armed Forces in the 21st Century

    Science.gov (United States)

    1999-12-01

    161-162; and Liu Mingtao and Yang Chengjun, Gao jushu zhanzheng zhong de daodan zhan (Missile Wars During High Tech Warfare), Beijing : Guofang daxue ...Guofang daxue chubanshe, 1996; Wang Pufeng, ed., Mao Zedong junshi zhanlue lun {On Mao Zedong’s Military Strategy), Beijing : Junshi kexue chubanshe...Science, Technology and Industry), Beijing : Guofang gongye chubanshe, pp. 157-159; Wu Jianguo, "Gaojishu zhanzheng zhong de he yinying bu rong

  17. International Conference on Organometallic Chemistry (13th) Held in Torino, Europe on 4-9 September 1988. Abstracts

    Science.gov (United States)

    1988-09-09

    190, 8057 ZUrich, Switzerland Joseph Edwin and William E.Geiger, Department of Chemistry, University of Vermont, Burlington, Vermont, 05405 Arnold L...On Synthesis Of Dialkyl d-Trimethylsilyloxyalkylphosphonates Zhao Yong-Zhen and Li Zhong- Rua Dpartment o chemistry, Hua Zhong Normal University, Wuhan...Jose Vicente. Jose-AntelC hAd. Na-Yeij~xa Qhicote. Ju~an-Francisco Gutliez-Jugo. Carmen Ramirez do Arel lano. Departamento do Oulmica InordanIca

  18. Identidad y ética en los Comentarios reales de los incas del Inca Garcilaso de la Vega

    DEFF Research Database (Denmark)

    Jensen, Hans Julio Casado

    2003-01-01

    Inca Garcilaso de la Vega. Historiografi. Renæssance. Spaniens erobring af Amerika. Etik. Paul Ricoeur......Inca Garcilaso de la Vega. Historiografi. Renæssance. Spaniens erobring af Amerika. Etik. Paul Ricoeur...

  19. Mida ütleb meile kõrgustesse vaatav eksistentsialism? / Jan Kaus

    Index Scriptorium Estoniae

    Kaus, Jan, 1971-

    2009-01-01

    Arvustus : Kierkegaard, Søren. Ängi mõiste. Tartu : Ilmamaa, 2008 ; Kierkegaard, Søren. Filosoofilised pudemed. Tartu : Ilmamaa, 2008 ; Kierkegaard, Søren. Surmatõbi : [kristlik-psühholoogiline mõttearendus meeleülenduseks ja äratamiseks]. Tartu : Ilmamaa, 2006

  20. Graphene Nanoplatelet Reinforced Tantalum Carbide

    Science.gov (United States)

    2015-08-27

    properties of nanocomposites at low graphene content, ACS Nano 3 (2009) 3884–3890. [4] S. Yang, G. Cui, S. Pang, Q. Cao, U. Kolb , X. Feng, et al...2010;20:2801–6. [9] Yang S, Cui G, Pang S, Cao Q, Kolb U, Feng X, et al. Fabrication of cobalt and cobalt oxide/graphene composites: towards high

  1. Maryam Moslemi, Sharghi, Mehdi Zahravi, Gholamreza Bakhshi ...

    African Journals Online (AJOL)

    01

    2013-08-21

    Aug 21, 2013 ... Briefly, Young leaves (100 mg) were ground to a fine powder in liquid nitrogen and ..... Yuan Z, Chen X, He T, Feng J, Feng T, Zhang C (2007b). Population genetic structure in apricot (Prunus armeniaca L.) cultivars revealed.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. QING-XIAN HUANG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 547-554 Article. Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway · LI-MIN FENG XUE-FENG WANG ...

  3. DMPD: The role of type I interferon production by dendritic cells in host defense. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available e. Fitzgerald-Bocarsly P, Feng D. Biochimie. 2007 Jun-Jul;89(6-7):843-55. Epub 2007 May 8. (.png) (.svg) (.h...fense. Authors Fitzgerald-Bocarsly P, Feng D. Publication Biochimie. 2007 Jun-Jul;89(6-7):843-55. Epub 2007

  4. Verification of the utility of molecular markers linked to the multiple ...

    African Journals Online (AJOL)

    GREGORY

    2010-08-30

    Aug 30, 2010 ... Feng Hui*, Wang Lili, Wei Peng, Liu Zhiyong, Li Chengyu, Wang Yugang, Ji Ruiqin and Zhang. Huaqing ..... Chin. Agric. Sci. Bull. 22: 377-379. Li CY, Feng H, Wei P, Wang LL, Zhang J, Yang HN, Jiang N (2009). Directional transfer of the genic multiple allele inherited male sterile line in Chinese cabbage.

  5. General Lp-harmonic Blaschke bodies

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 124; Issue 1. General -Harmonic Blaschke Bodies. Yibin Feng Weidong Wang. Volume 124 Issue 1 February 2014 pp ... Author Affiliations. Yibin Feng1 Weidong Wang1. Department of Mathematics, China Three Gorges University, Yichang 443002, China ...

  6. Molecular and Ultrastructural Mechanisms Underlying Yellow Dwarf Symptom Formation in Wheat after Infection of Barley Yellow Dwarf Virus.

    Science.gov (United States)

    Rong, Wei; Wang, Xindong; Wang, Xifeng; Massart, Sebastien; Zhang, Zengyan

    2018-04-13

    Wheat ( Tritium aestivum L.) production is essential for global food security. Infection of barley yellow dwarf virus-GAV (BYDV-GAV) results in wheat showing leaf yellowing and plant dwarfism symptom. To explore the molecular and ultrastructural mechanisms underlying yellow dwarf symptom formation in BYDV-GAV-infected wheat, we investigated the chloroplast ultrastructure via transmission electron microscopy (TEM), examined the contents of the virus, H₂O₂, and chlorophyll in Zhong8601, and studied the comparative transcriptome through microarray analyses in the susceptible wheat line Zhong8601 after virus infection. TEM images indicated that chloroplasts in BYDV-GAV-infected Zhong8601 leaf cells were fragmentized. Where thylakoids were not well developed, starch granules and plastoglobules were rare. Compared with mock-inoculated Zhong8601, chlorophyll content was markedly reduced, but the virus and H₂O₂ contents were significantly higher in BYDV-GAV-infected Zhong8601. The transcriptomic analyses revealed that chlorophyll biosynthesis and chloroplast related transcripts, encoding chlorophyll a/b binding protein, glucose-6-phosphate/phosphate translocator 2, and glutamyl-tRNA reductase 1, were down-regulated in BYDV-GAV-infected Zhong8601. Some phytohormone signaling-related transcripts, including abscisic acid (ABA) signaling factors (phospholipase D alpha 1 and calcineurin B-like protein 9) and nine ethylene response factors, were up-regulated. Additionally, reactive oxygen species (ROS)-related genes were transcriptionally regulated in BYDV-GAV infected Zhong8601, including three up-regulated transcripts encoding germin-like proteins (promoting ROS accumulation) and four down-regulated transcripts encoding peroxides (scavenging ROS). These results clearly suggest that the yellow dwarf symptom formation is mainly attributed to reduced chlorophyll content and fragmentized chloroplasts caused by down-regulation of the chlorophyll and chloroplast biosynthesis

  7. Prognostic impact of body mass index stratified by smoking status in patients with esophageal squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Sun P

    2016-10-01

    Full Text Available Peng Sun,1,2,* Fei Zhang,1,2,* Cui Chen,3,* Chao Ren,1,2 Xi-Wen Bi,1,2 Hang Yang,1,2 Xin An,1,2 Feng-Hua Wang,1,2 Wen-Qi Jiang1,2 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 2Department of Medical Oncology, Sun Yat-Sen University Cancer Center, 3Department of Oncology, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Background: As smoking affects the body mass index (BMI and causes the risk of esophageal squamous cell carcinoma (ESCC, the prognostic impact of BMI in ESCC could be stratified by smoking status. We investigated the true prognostic effect of BMI and its potential modification by smoking status in ESCC. Methods: We retrospectively analyzed 459 patients who underwent curative treatment at a single institution between January 2007 and December 2010. BMI was calculated using the measured height and weight before surgery. Chi-square test was used to evaluate the relationships between smoking status and other clinicopathological variables. The Cox proportional hazard models were used for univariate and multivariate analyses of variables related to overall survival. Results: BMI <18.5 kg/m2 was a significantly independent predictor of poor survival in the overall population and never smokers after adjusting for covariates, but not in ever smokers. Among never smokers, underweight patients (BMI <18.5 kg/m2 had a 2.218 times greater risk of mortality than non-underweight (BMI =18.5 kg/m2 patients (P=0.015. Among ever smokers, BMI <18 kg/m2 increased the risk of mortality to 1.656 (P=0.019, compared to those having BMI =18 kg/m2. Conclusion: Our study is likely the first to show that the prognostic effect of BMI was substantial in ESCC, even after stratifying by smoking status. Furthermore, the risk of death due to low BMI would be significantly increased in never smokers. We believe that

  8. Reduced prefrontal activation during verbal fluency task in chronic insomnia disorder: a multichannel near-infrared spectroscopy study

    Directory of Open Access Journals (Sweden)

    Sun JJ

    2017-06-01

    Full Text Available Jing-Jing Sun,1,2 Xiao-Min Liu,2 Chen-Yu Shen,2 Xiao-Qian Zhang,1,2 Gao-Xiang Sun,2 Kun Feng,2 Bo Xu,2 Xia-Jin Ren,1,2 Xiang-Yun Ma,1,2 Po-Zi Liu2 1Medical Center, Tsinghua University, Beijing, China, 2Department of Psychiatry, YuQuan Hospital, Tsinghua University, Beijing, China Purpose: Daytime complaints such as memory and attention deficits and failure to accomplish daily tasks are common in insomnia patients. However, objective psychological tests to detect cognitive impairment are equivocal. Neural function associated with cognitive performance may explain the discrepancy. The aim of this study was to investigate the hemodynamic response patterns of patients with chronic insomnia disorder (CID using the noninvasive and low-cost functional neuroimaging technique of multichannel near-infrared spectroscopy (NIRS in order to identify changes of neural function associated with cognitive performance.Patients and methods: Twenty-four CID patients and twenty-five healthy controls matched for age, right-hand dominance, educational level, and gender were examined during verbal fluency tasks (VFT using NIRS. A covariance analysis was conducted to analyze differences of oxygenated hemoglobin (oxy-Hb changes in prefrontal cortex (PFC between the two groups and reduce the influence of the severity of depression. Pearson correlation coeffcients were calculated to examine the relationship between the oxy-Hb changes, with the severity of insomnia and depressive symptoms assessed by the Pittsburgh Sleep Quality Index (PSQI and the Hamilton Rating Scale for Depression (HAMD.Results: The number of words generated during the VFT in CID groups showed no statistical differences with healthy controls. CID patients showed hypoactivation in the PFC during the cognitive task. In addition, we found that the function of left orbitofrontal cortex (OFC during the VFT was significantly negatively correlated with the PSQI scores and the function of right dorsolateral PFC

  9. A novel redox-sensitive system based on single-walled carbon nanotubes for chemo-photothermal therapy and magnetic resonance imaging

    Directory of Open Access Journals (Sweden)

    Hou L

    2016-02-01

    Full Text Available Lin Hou,1,2 Xiaomin Yang,1 Junxiao Ren,1 Yongchao Wang,1 Huijuan Zhang,1 Qianhua Feng,1 Yuyang Shi,1 Xiaoning Shan,1 Yujie Yuan,1 Zhenzhong Zhang1,21School of Pharmaceutical Sciences, Zhengzhou University, Henan Province, Zhengzhou, People’s Republic of China; 2Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province, Zhengzhou, People’s Republic of ChinaAbstract: Recently, nanomaterials with multiple functions, such as drug carrier, magnetic resonance imaging (MRI and optical imaging, and photothermal therapy, have become more and more popular in cancer research. In this work, a novel redox-sensitive system constructed from hyaluronic acid (HA, single-walled carbon nanotubes (SWCNTs, doxorubicin (DOX, and gadolinium (Gd was successfully developed. Herein, HA-modified SWCNTs (SWCNTs-HA was first synthesized, and then DOX was conjugated with HA by disulfide bond (SWCNTs-HA-ss-DOX. Finally, MRI contrast agents, Gd3+-ion loading occurred through the sidewall defects of SWCNTs, whose cytotoxicity could be sequestered within the SWCNTs. In vitro release of DOX showed that this system accomplished much faster drug release under reducing condition. Confocal microscopy analysis confirmed that Gd/SWCNTs-HA-ss-DOX were capable of simultaneously delivering DOX and SWCNTs into Michigan Cancer Foundation-7 cells via HA receptor-mediated endocytosis followed by rapid transport of cargoes into the cytosol. Enhanced cytotoxicity of Gd/SWCNTs-HA-ss-DOX further proved that the sensitive system was more potent for intracellular drug delivery as compared with the insensitive control. Meanwhile, tumor cell killing potency was improved when Gd/SWCNTs-HA-ss-DOX were combined with near-infrared irradiation, with IC50 of 0.61 µg/mL at 48 hours. In vivo investigation demonstrated that Gd/SWCNTs-HA-ss-DOX could effectively accumulate in tumor sites and possessed the greatest synergistic antitumor efficacy, especially under the 808 nm

  10. Subtype classification for prediction of prognosis of breast cancer from a biomarker panel: correlations and indications

    Directory of Open Access Journals (Sweden)

    Chen C

    2014-02-01

    Full Text Available Chuang Chen,1 Jing-Ping Yuan,2,3 Wen Wei,1 Yi Tu,1 Feng Yao,1 Xue-Qin Yang,4 Jin-Zhong Sun,1 Sheng-Rong Sun,1 Yan Li2 1Department of Breast and Thyroid Surgery, Wuhan University, Renmin Hospital, Wuhan, 2Department of Oncology, Zhongnan Hospital of Wuhan University and Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, 3Department of Pathology, The Central Hospital of Wuhan, Wuhan, 4Medical School of Jingchu University of Technology, Jingmen, People’s Republic of China Background: Hormone receptors, including the estrogen receptor and progesterone receptor, human epidermal growth factor receptor 2 (HER2, and other biomarkers like Ki67, epidermal growth factor receptor (EGFR, also known as HER1, the androgen receptor, and p53, are key molecules in breast cancer. This study evaluated the relationship between HER2 and hormone receptors and explored the additional prognostic value of Ki67, EGFR, the androgen receptor, and p53. Methods: Quantitative determination of HER2 and EGFR was performed in 240 invasive breast cancer tissue microarray specimens using quantum dot (QD-based nanotechnology. We identified two subtypes of HER2, ie, high total HER2 load (HTH2 and low total HER2 load (LTH2, and three subtypes of hormone receptor, ie, high hormone receptor (HHR, low hormone receptor (LHR, and no hormone receptor (NHR. Therefore, breast cancer patients could be divided into five subtypes according to HER2 and hormone receptor status. Ki67, p53, and the androgen receptor were determined by traditional immunohistochemistry techniques. The relationship between hormone receptors and HER2 was investigated and the additional value of Ki67, EGFR, the androgen receptor, and p53 for prediction of 5-year disease-free survival was assessed. Results: In all patients, quantitative determination showed a statistically significant (P<0.001 negative correlation between HER2 and the hormone receptors and a significant

  11. Experimental study of the protective effects of Zhongfei decoction on radiation-induced pneumonia in rats

    International Nuclear Information System (INIS)

    Wang Yuezhen; Ma Shenglin; Zhang Aiqin; Feng Jianguo; Fang Xianhua; Sun Xiaojiang; Bao Yejiang

    2007-01-01

    Objective: To investigate the protective effect and its possible mechanism of ZhongFei Decoction on radiation-induced pneumonia in rats. Methods: Single irradiation was given at two thorax of female Wistar rats with 30 Gy of 6 MV X irradiation. Sixty rats were randomly divided into the control group, radiation group, radiation plus DXM and ZhongFei Decoction plus radiation group. On days 14 and 28 after treatment, 5 rats of each group were sacrificed, and their lungs were harvested for measurement of the lung index, the difference of the histopathology change, the concentration of hydroxyproline (hyp), and expression of transforming growth factor-β1 in lungs were analyzed by HE stain, biochemical method and immunohistochemical method, respectively. Results: The pathological study showed marked lung injury in the radiation group while only slight hyperemia hemorrhage, exudation and thickness of alveolar walls in the lungs of ZhongFei Decoction plus radiation group, the concentration of hydroxyproline and expression of TGF-β1 in the radiation lungs increased compared with that in the control group and reduced in the ZhongFei Decoction plus radiation group compared with that in the radiation group. Conclusions: ZhongFei Decoction could have protective effects on the radiation-induced pneumonia and the mechanism of its may be related with down-regulating the expression of TGF-β1 in the irritated lung tissue. (authors)

  12. The missing evaluation codes from order domain theory

    DEFF Research Database (Denmark)

    Andersen, Henning Ejnar; Geil, Olav

    The Feng-Rao bound gives a lower bound on the minimum distance of codes defined by means of their parity check matrices. From the Feng-Rao bound it is clear how to improve a large family of codes by leaving out certain rows in their parity check matrices. In this paper we derive a simple lower...... generalized Hamming weight. We interpret our methods into the setting of order domain theory. In this way we fill in an obvious gap in the theory of order domains. The improved codes from the present paper are not in general equal to the Feng-Rao improved codes but the constructions are very much related....

  13. Piezoelectric Nanogenerators for Self-Powered Nanosystems and Nanosensors

    Science.gov (United States)

    2013-05-15

    researchers 1. Sangmin Lee, Sung-Hwan Bae, Long Lin, Seunghyun Ahn, Chan Park, Seung Nam Cha, Young Jun Park, Hyuk Chang, Sang-Woo Kim and...Sohn, Seung Nam Cha, Dukhyun Choi * Zhong Lin Wang * Sang-Woo Kim * “ P-Type Polymer–Hybridized High-Performance Piezoelectric Nanogenerators”, Nano...Yoon Lee, † Sang-Woo Kim , *,$ Jae-Young Choi, *,† Jong Min Kim , † and Zhong Lin Wang *, “Flexible Hybrid Multi-Type Energy Scavenger”, Energy

  14. Multiscale Numerical Methods for Non-Equilibrium Plasma

    Science.gov (United States)

    2015-08-01

    Smith Chris Anderson Xiaolin Zhong Jean-Luc Cambier Ann Karagozian, Committee Chair University of California, Los Angeles 2012 iv E-7 To my mother...of my committee, Professor Xiaolin Zhong and Professor Chris Anderson, for their guidance. I would like to thank my current and past labmates, Chris ...detonations. Phys. Fluids, 15:112–122, 2003. 221 E-246 [15] H. D. Ng, A. J. Higgins , C. B. Kiyanda, M. I. Radulescu, J. H. S. Lee, K. R. Bates, and N

  15. African Journal of Biotechnology - Vol 12, No 31 (2013)

    African Journals Online (AJOL)

    induced fatty liver model of consecutive extracts from Rosa davurica Pall · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ying Wei, Muyi Cai, Ruizeng Gu, Jun Lu, Feng Lin, Baoping Ji ...

  16. Yuan and Jing Afr J Tradit Complement Altern Med. (2011) 8(2):104 ...

    African Journals Online (AJOL)

    USER

    kinase C, which participates in ischemic neuron injury, and plays an important role in the ... pharmaceutical effects including two-way regulations of blood glucose and immunologic ..... positive cell-cycle regulating agent (Feng et al., 2008a).

  17. The characterization of cytoplasmic ribosomal protein genes - AJOL

    African Journals Online (AJOL)

    USER

    2012-04-17

    weblogo.berkeley.edu/logo.cgi). ... method (Saitou and Nei, 1987) implemented in MEGA 4.0 program ..... (Figure 3), indicating selection for efficient recognition by ..... Akiyoshi DE, Morrison HG, Lei S, Feng X, Zhang Q, Corradi N, ...

  18. 1,6-Diaminoperylene bisimide with a highly twisted perylene core

    Indian Academy of Sciences (India)

    ... KEW-YU CHEN. ∗. Department of Chemical Engineering, Feng Chia University, 40724 Taichung, Taiwan, Republic of China ... chromic materials,6 and organic field-effect transis- ..... Wasielewski M R 2012 Competition between singlet fis-.

  19. Effects of quantum coupling on the performance of metal-oxide ...

    Indian Academy of Sciences (India)

    LING-FENG MAO. School of Electronics & Information Engineering, Soochow University, ... Quantum coupling; metal-oxide-semiconductor field transistors. ... effects of the barrier height reduction caused by the channel electron velocity due to.

  20. Ubiquitous distribution of fluorescent protein in muscles of four ...

    Indian Academy of Sciences (India)

    In this study, the localization of fluorescent protein (FP) was characterized in the muscles of ... A. mossambica have four exons and three introns, and were common to that of FABP family. ..... organization of the neurons (Rakic 1971; Feng et al.