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Sample records for remarkably effective copperii-dipyridylphosphine

  1. Some remarks about large p/sub perpendicular/ spin effects

    International Nuclear Information System (INIS)

    Field, R.D.

    1977-01-01

    A discussion of the ingredients necessary to make predictions concerning single and double spin measurements in large p/sub perpendicular to/ inclusive processes is presented. Remarks are made as to what might be expected and what might be learned from such measurements. Various models for the production of large p/sub perpendicular to/ mesons have quite different spin structure and hence can be expected to give differing predictions. However, it is not possible at this time to make quantitative calculations, and it is possible (not probable) that the interesting spin observables will be negligibly small

  2. The Remarkable Beneficial Effect of Adding Oral Simvastatin to ...

    African Journals Online (AJOL)

    Psoriasis is a common chronic inflammatory disease with unpredictable prognosis. Given the immunomodulatory effects of statins, the present study was conducted to determine whether the addition of orally administered simvastatin to the topical betamethasone, a standard antipsoriatic treatment, can produce a more ...

  3. Opening remarks

    International Nuclear Information System (INIS)

    Southwood, Richard

    1987-01-01

    General opening remarks to a conference on the effects of low-level radiation on man, exploring particularly areas where disagreements have most frequently been voiced. The author comments on two approaches: a) the study, stepwise of putative cause and effect chains, using models which are tested by comparing calculated and observed effects. b) the epidemiological approach by extensive correlative study of cause, correlations and effect. Attention is drawn to the confidence to be accorded to any quantitative theory supported by both approaches, and the need for further analysis if the approaches give different indications. (U.K.)

  4. Opening remarks

    International Nuclear Information System (INIS)

    Kyd, D.R.

    1993-11-01

    In his opening remarks Mr. David R. Kyd briefly described the IAEA mission. Then he outlined main aim of the seminar which is bring together journalists, educators, officials and other specialists to let them hear and put questions to experts on various aspects of nuclear energy and techniques. Further he analyzed problems and prospects of energy development in Asia and particularly in China, including environmental considerations. The final part of the remarks was devoted comparative evaluation of different energy production technologies

  5. Concluding remarks

    International Nuclear Information System (INIS)

    Nariai, H.

    2007-01-01

    This document provides the speech presented by Hideki Nariai on May 2007 at the workshop on transparency of nuclear regulatory activities. It aims to propose concluding remarks concerning nuclear safety and the necessity to be transparent to the general public. (A.L.B.)

  6. The remarkable robustness of the first-offer effect: across culture, power, and issues.

    Science.gov (United States)

    Gunia, Brian C; Swaab, Roderick I; Sivanathan, Niro; Galinsky, Adam D

    2013-12-01

    The first-offer effect demonstrates that negotiators achieve better outcomes when making the first offer than when receiving it. The evidence, however, primarily derives from studies of Westerners without systematic power differences negotiating over one issue-contexts that may amplify the first-offer effect. Thus, the present research explored the effect across cultures, among negotiators varying in power, and in negotiations involving single and multiple issues. The first two studies showed that the first-offer effect remains remarkably robust across cultures and multi-issue negotiations. The final two studies demonstrated that low-power negotiators benefit from making the first offer across single- and multi-issue negotiations. The second and fourth studies used multi-issue negotiations with distributive, integrative, and compatible issues, allowing us to show that first offers operate through the distributive, not the integrative or compatible issues. Overall, these results reveal that moving first can benefit negotiators across many organizational and personal situations.

  7. Concluding remarks

    International Nuclear Information System (INIS)

    Patrick, W.C.

    1996-01-01

    This section contains the concluding remarks of the workshop on rock mechanics issues in repository design and performance assessment. Technical issues such as spatial variability of rock properties, rock mass strength, measurement of loads, evaluation of long-term seal performance, and integration of data into design were discussed. Programmatic issues such as development of a coherent and consistent design methodology and implementation of that methodology were also reiterated

  8. Welcome remarks

    International Nuclear Information System (INIS)

    Zhao Hong

    1993-01-01

    In his opening remarks Mr. Zhao Hong stressed the importance of nuclear power for further economic development. He noticed that one of the main factors to obstruct the progress of nuclear energy is nuclear dread in public psychology and that enhancement of the public acceptance of nuclear power is an important task to promote the development of nuclear power. Than he described activities in China in public relation work in the field of nuclear energy. Importance of international cooperation on peaceful use of nuclear energy and supporting non-proliferation regime was stressed

  9. Concluding remarks

    International Nuclear Information System (INIS)

    Vogt, E.

    1989-05-01

    The workshop has covered in a very interesting and complete way the basic physics issues to be addressed by the complementary facilities, in Canada and Japan, intended to explore the intensity-frontier of strong-interaction physics. Japan has its new KEK facilities and its future Japanese Hadron Project (JHP): Canada has its present TRIUMF laboratory and its future KAON Factory. Both JHP and KAON appear very near to final construction approval. The possibilities are very great for new joint programs between the two countries which can lead the world in the new strong interaction physics. These concluding remarks describe the general science basis and particularly the models for the internationalization of science needed to make these new collaborations thrive

  10. The remarkable environmental rebound effect of electric cars: a microeconomic approach.

    Science.gov (United States)

    Font Vivanco, David; Freire-González, Jaume; Kemp, René; van der Voet, Ester

    2014-10-21

    This article presents a stepwise, refined, and practical analytical framework to model the microeconomic environmental rebound effect (ERE) stemming from cost differences of electric cars in terms of changes in multiple life cycle environmental indicators. The analytical framework is based on marginal consumption analysis and hybrid life cycle assessment (LCA). The article makes a novel contribution through a reinterpretation of the traditional rebound effect and methodological refinements. It also provides novel empirical results about the ERE for plug-in hybrid electric (PHE), full-battery electric (FBE), and hydrogen fuel cell (HFC) cars for Europe. The ERE is found to have a remarkable impact on product-level environmental scores. For the PHE car, the ERE causes a marginal increase in demand and environmental pressures due to a small decrease in the cost of using this technology. For FBE and HFC cars, the high capital costs cause a noteworthy decrease in environmental pressures for some indicators (negative rebound effect). The results corroborate the concern over the high influence of cost differences for environmental assessment, and they prompt sustainable consumption policies to consider markets and prices as tools rather than as an immutable background.

  11. Closing remarks

    International Nuclear Information System (INIS)

    Reig, J.

    2007-01-01

    Good afternoon. Before providing the closing remarks on behalf of the NEA, I would like to take this opportunity and make some personal reflections, if you allow me Mr. Chairman. I have had the opportunity to take part in the three workshops on public communication organised by the NEA. In the first one in Paris in 2000, representing my country, Spain, and in the two last ones in Ottawa in 2004 and Tokyo today, on behalf of the NEA. The topics for the three workshops follow a logical order, first the focus was on investing in trust in a time when public communication was becoming a big challenge for the regulators. Second, maintaining and measuring public confidence to assess how credible regulators are in front of the public; and finally here in Tokyo, transparency, which is a basic element to achieve trust and credibility. In my view, a regulatory decision has three main components, it has to be technically sound. legally correct and well communicated. The emphasis in the early years was in the technical matters, till legal issues became a key element to achieve the political acceptance from governments and local authorities. Finally the public communication aspects resulted into a major effort and challenge to achieve social acceptance. (author)

  12. Certifying Effect and Consumer Effect: Some Remarks on Strategies Employed by Higher Education Institutions.

    Science.gov (United States)

    Girod de l'Ain, Bertrand

    1981-01-01

    Institutions wishing to increase the perceived value of their degrees or awards do so by increasing demand for those degrees, by stimulating applications for admission (the certifying effect) and even reducing graduates. Receipt of one of these degrees increases chances of success and affluence (the consumer effect). (MSE)

  13. Concluding remarks

    International Nuclear Information System (INIS)

    Wilkinson, D.H.

    1996-06-01

    This paper reviews the shift in the emphasis of the conference series that began as the International Conference on High Energy Physics and Nuclear Structure (1963) and evolved to the Particle and Nuclei International Conferences, PANIC, the latest of which was held at CEBAF in 1996. The author reviews the papers presented leading to a better appreciation of the EMC effect,, recent understanding of QCD-based effects and the quark structure of the neutron. The author examines the future roles of HERA and CEBAF in the extension of improved experiments on nuclear structure

  14. Closing remarks

    International Nuclear Information System (INIS)

    Osborne, R.V.

    1988-01-01

    Where are the gaps in our current knowledge and what research is needed? One of my concerns was whether those of us in the radiation protection community have been thinking along the same lines as people in the field of toxicology. I think what has been evident that the problems and issues are very similar. Very evident common problems are those of extrapolation of observed toxic effects at high doses to predictions of effects at low doses; of the applicability of information obtained from one animal species to another; the public pressures to define risk (perhaps not pressures to define this goal as much as to define what is safe); the problems of multiple exposures; and the lack of money and resources to do all the things that it seems should be done. These are all problems familiar to us in the radiation protection community

  15. Final remarks

    International Nuclear Information System (INIS)

    1998-01-01

    This document presents the fulfilling of the Brazilian obligations under the Convention on Nuclear Safety. The Chapter 7 of the document refers to the achievement and maintenance of a high level in the Brazilian nuclear installations, the establishment and maintenance of effective defenses against potential radiological hazards, the ability to prevent accidents with radiological consequences and preparedness for mitigating the consequences of such accidents should they occur

  16. Introductory remarks

    International Nuclear Information System (INIS)

    Pecker, J.-C.; Runcorn, S.K.

    1990-01-01

    The search for periodic or quasi-periodic variations in the solar constant through the analysis of climatic and meteorological data has proved elusive. The reason is evident: the atmosphere is a wet gas with much energy stored as latent heat and is in complex interaction dynamically and thermally with the oceans and land areas. The instabilities, what we call the weather, cause not only day-to-day but also year-to-year variations so great that small changes due to fluctuations of the energy input from the Sun may be masked. Yet, as the seasonal changes of solar energy falling on each hemisphere result in such obvious effects, it should not be impossible to detect in the climatic records much smaller changes in the total global input of heat energy into the atmosphere, especially if these are cyclical, by integrating out short-term fluctuations. Terrestrial phenomena which might be associated with solar behaviour such as tree-ring growth, drought, heavy rains, air temperature are of great interest. There is evidence from these sources of longer cycles of solar activity which may have a period of between 100 and 200 years but with the data available this is difficult to prove. The issue is complicated by variations in geomagnetic activity. A new source of information on solar activity is the spectrum of 14 C variations from during the past millenia from tree rings and this has prompted further studies of variations in the sun and climate to be undertaken. (author)

  17. PREFACE: Introductory remarks Introductory remarks

    Science.gov (United States)

    Bowler, D. R.; Alfe, D.

    2010-02-01

    This special issue contains papers related to the 2009 Thomas Young Centre Workshop at University College London 'Accessing large length and time scales with accurate quantum methods', in celebration of Professor Michael Gillan's 65th birthday. Mike Gillan won the 2006 Institute of Physics Dirac Medal and Prize, the citation reading: 'For his contributions to the development of atomic-scale computer simulations, which have greatly extended their power and effectiveness over an immense range of applications'. This rightly highlights Mike's seminal work on materials modelling, but misses out some of the many other areas he has enriched. After taking his PhD at the Department of Theoretical Physics, Oxford University, Mike went as a post-doc to Minneapolis. He then joined the Statistical Physics Group in the Theoretical Physics Division, Harwell, where he stayed for over 20 years, with a brief interlude in Saclay. In the late 1980s, Mike made a transition to become Professor of Physics at the University of Keele, where he stayed for a decade until University College London was fortunate in being able to tempt him to join the Condensed Matter and Material Physics Group, where there was already a significant materials modelling initiative. Over the years, Mike has made many important contributions, some with impact on other areas of science, others with significance in technology areas such as nuclear safety. Thus, he developed a form of quantum transition-state theory, generalizing Eyring's well-known classical transition-state theory to the case of quantum particles, such as hydrogen, diffusing in condensed matter. He pioneered quantum methods for calculating defect energetics in solids, and then molecular processes on surfaces. He synthesised these approaches into very general ways to calculate thermodynamic free energies of condensed matter from first principles, drawing on his early experience of statistical physics. These methods led to rapid advances in the study

  18. Remarkable nanoconfinement effects on chemical equilibrium manifested in nucleotide dimerization and H-D exchange reactions.

    Science.gov (United States)

    Polak, Micha; Rubinovich, Leonid

    2011-10-06

    Nanoconfinement entropic effects on chemical equilibrium involving a small number of molecules, which we term NCECE, are revealed by two widely diverse types of reactions. Employing statistical-mechanical principles, we show how the NCECE effect stabilizes nucleotide dimerization observed within self-assembled molecular cages. Furthermore, the effect provides the basis for dimerization even under an aqueous environment inside the nanocage. Likewise, the NCECE effect is pertinent to a longstanding issue in astrochemistry, namely the extra deuteration commonly observed for molecules reacting on interstellar dust grain surfaces. The origin of the NCECE effect is elucidated by means of the probability distributions of the reaction extent and related variations in the reactant-product mixing entropy. Theoretical modelling beyond our previous preliminary work highlights the role of the nanospace size in addition to that of the nanosystem size, namely the limited amount of molecules in the reaction mixture. Furthermore, the NCECE effect can depend also on the reaction mechanism, and on deviations from stoichiometry. The NCECE effect, leading to enhanced, greatly variable equilibrium "constants", constitutes a unique physical-chemical phenomenon, distinguished from the usual thermodynamical properties of macroscopically large systems. Being significant particularly for weakly exothermic reactions, the effects should stabilize products in other closed nanoscale structures, and thus can have notable implications for the growing nanotechnological utilization of chemical syntheses conducted within confined nanoreactors.

  19. Some remarks on the effects of drugs, lack of sleep and loud noise on human performance.

    NARCIS (Netherlands)

    Sanders, A.F. & A.A. Bunt.

    1971-01-01

    Some literature is reviewed on the effect of some drugs, (amphetamine, hypnotics, alcohol), loud noise and sleep loss in test of time estimation, decision making, long term performance and short term memory. Results are most clear with respect to amphetamine, hypnotics and lack of sleep, in that

  20. Remarkable effects of disorder on superconductivity of single atomic layers of lead on silicon

    Science.gov (United States)

    Brun, Christophe

    2015-03-01

    It is well known that conventional superconductivity is very robust against non-magnetic disorder. Nevertheless for thin and ultrathin films the structural properties play a major role in determining the superconducting properties, through a subtle interplay between disorder and Coulomb interactions. Unexpectedly, in 2010 superconductivity was discovered in single atomic layers of lead and indium grown on silicon substrate using scanning tunneling spectroscopy and confirmed later on by macroscopic transport measurements. Such well-controlled and tunable crystalline monolayers are ideal systems for studying the influence of various kinds of structural defects on the superconducting properties at the atomic and mesoscopic scale. In particular, Pb monolayers offer the opportunity of probing new effects of disorder because not only superconductivity is 2D but also the electronic wave functions are 2D. Our study of two Pb monolayers of different crystal structures by very-low temperature STM (300 mK) under magnetic field reveals unexpected results involving new spatial spectroscopic variations. Our results show that although the sheet resistance of the Pb monolayers is much below the resistance quantum, strong non-BCS corrections appear leading to peak heights fluctuations in the dI/dV tunneling spectra at a spatial scale much smaller than the superconducting coherence length. Furthermore, strong local evidence of the signature of Rashba effect on the superconductivity of the Pb/Si(111) monolayer is revealed through filling of in gap states and local spatial variations of this filling. Finally the nature of vortices in a monolayer is found to be very sensitive to the properties of step edges areas. This work was supported by University Pierre et Marie Curie UPMC `Emergence' project, French ANR Project `ElectroVortex,' ANR-QuDec and Templeton Foundation (40381), ARO (W911NF-13-1-0431) and CNRS PICS funds. Partial funding by US-DOE Grant DE-AC02-07CH1.

  1. Near fatal 5-FU gut toxicity post surgery--remarkable effect of high-dose sucralfate.

    Science.gov (United States)

    Toh, James Wei Tatt; Morris, David; Chen, Zhuoran; Chen, Cindy

    2015-06-01

    The objective of this review article and case report was to investigate the effectiveness of high-dose sucralfate on severe life-threatening 5-fluorouracil (5-FU) gut toxicity, with reference to, but not limited to dihydropyrimidine dehydrogenase (DPD) deficiency. A search was conducted on PubMed from 1950 to July 2013 for original studies on 5-FU gut toxicity and sucralfate. Studies were limited to human trials and English language and all articles included in this study were assessed with the application of predetermined selection criteria. Each article was then reviewed independently by two reviewers. A case report from our own centre was included in this review. From 33 results, 6 manuscripts were identified including 4 randomized controlled trial. One trial evaluated the use of sucralfate to alleviate stomatitis in patients with 5-FU-based chemotherapy. The other three trials evaluated the role of sucralfate in radiation toxicity. There was one case report which showed gastroscopy confirmed normalization of severe dysplastic erosive gastroduodenitis attributed to hepatic arterial infusion of 5-FU following a 2-month course of sucralfate and cimetidine and one case series showing clinical and sigmoidoscopically demonstrated improvement in ulcerative colitis in majority of patients receiving sucralfate enemas. There was no current literature specifically focussed on the role of sucralfate in 5-FU gut toxicity. Our case report describes the clinical course and successful treatment with sucralfate of a patient with Pseudomyxoma peritonei (PMP) who experienced 5-FU gut toxicity resulting in life-threatening bleeding due to presumed DPD deficiency post intraperitoneal 5-FU administration. This review article showed a lack of literature concerning the use of sucralfate in 5-FU gut toxicity. In our patient's case, sucralfate had a crucial role in the management of near fatal 5-FU gut toxicity, and further evaluation is required.

  2. Remarks on superconductive networks

    International Nuclear Information System (INIS)

    Dominguez, D.; Lopez, A.R.N.; Simonin, J.M.

    1989-01-01

    Some remarks on the determination of the normal-superconductor phase boundary in random superconductive networks are made. A recently reported work by Soukoulis, Grest and Li which introduces weak links between nodes as these are removed in the site percolation problem is discussed. By the analysis of two simple geometries, it is shown that this procedure introduces spurious effects which mask the physical properties of the system. These affect in particular the field slope critical index and the sharpness of the normal-superconductor boundary. (Author)

  3. Equivalence of hyperfractionated and continuous brachytherapy in a rat tumor model and remarkable effectiveness when preceded by external irradiation

    International Nuclear Information System (INIS)

    Veninga, Theo; Visser, Andries G.; Berg, Ad P. van den; Hooije, Christel van; Geel, Cornelis A.J.F. van; Levendag, Peter C.

    2001-01-01

    Purpose: In clinical brachytherapy, there is a tendency to replace continuous low-dose-rate (LDR) irradiation by either single-dose or fractionated high-dose-rate (HDR) irradiation. In this study, the equivalence of LDR treatments and fractionated HDR (2 fractions/day) or pulsed-dose-rate (PDR, 4 fractions/day) schedules in terms of tumor cure was investigated in an experimental tumor model. Methods and Materials: Tumors (rat rhabdomyosarcoma R1M) were grown s.c. in the flank of rats and implanted with 4 catheters guided by a template. All interstitial radiation treatment (IRT) schedules were given in the same geometry. HDR was given using an 192 Ir single-stepping source. To investigate small fraction sizes, part of the fractionated HDR and PDR schedules were applied after an external irradiation (ERT) top-up dose. The endpoint was the probability of tumor control at 150 days after treatment. Cell survival was estimated by excision assay. Results: Although there was no fractionation effect for fractionated HDR given in 1 or 2 fractions per day, TCD 50 -values were substantially lower than that for LDR. A PDR schedule with an interfraction interval of 3 h (4 fractions/day), however, was equivalent to LDR. The combination of ERT and IRT resulted in a remarkably increased tumor control probability in all top-up regimens, but no difference was found between 2 or 4 fractions/day. Catheter implantation alone decreased the TCD 50 for single-dose ERT already by 17.4 Gy. Cell viability assessed at 24 h after treatment demonstrated an increased effectiveness of interstitial treatment, but, after 10 Gy ERT followed by 10 Gy IRT (24-h interval), it was not less than that calculated for the combined effect of these treatments given separately. Conclusion: In full fractionation schedules employing large fractions and long intervals, the sparing effect of sublethal damage repair may be significantly counteracted by reoxygenation. During 3-h intervals, however, repair may be

  4. Novel VEGF decoy receptor fusion protein conbercept targeting multiple VEGF isoforms provide remarkable anti-angiogenesis effect in vivo.

    Directory of Open Access Journals (Sweden)

    Qin Wang

    Full Text Available VEGF family factors are known to be the principal stimulators of abnormal angiogenesis, which play a fundamental role in tumor and various ocular diseases. Inhibition of VEGF is widely applied in antiangiogenic therapy. Conbercept is a novel decoy receptor protein constructed by fusing VEGF receptor 1 and VEGF receptor 2 extracellular domains with the Fc region of human immunoglobulin. In this study, we systematically evaluated the binding affinity of conbercept with VEGF isoforms and PlGF by using anti-VEGF antibody (Avastin as reference. BIACORE and ELISA assay results indicated that conbercept could bind different VEGF-A isoforms with higher affinity than reference. Furthermore, conbercept could also bind VEGF-B and PlGF, whereas Avastin showed no binding. Oxygen-induced retinopathy model showed that conbercept could inhibit the formation of neovasularizations. In tumor-bearing nude mice, conbercept could also suppress tumor growth very effectively in vivo. Overall, our study have demonstrated that conbercept could bind with high affinity to multiple VEGF isoforms and consequently provide remarkable anti-angiogenic effect, suggesting the possibility to treat angiogenesis-related diseases such as cancer and wet AMD etc.

  5. Remarkable weakness against cleavage stress for YBCO-coated conductors and its effect on the YBCO coil performance

    International Nuclear Information System (INIS)

    Yanagisawa, Y.; Nakagome, H.; Takematsu, T.; Takao, T.; Sato, N.; Takahashi, M.; Maeda, H.

    2011-01-01

    Cleavage strength for YBCO-coated conductor is extremely low, typically 0.5 MPa. The remarkable weakness is due to cracks on the slit edge of the conductor. The cleavage stress appears on YBCO double pancake coils impregnated with epoxy. The cleavage stress should be avoided in the coil winding. Cleavage strength for an YBCO-coated conductor at 77 K was investigated with a model experiment. The nominal cleavage strength for an YBCO-coated conductor is extremely low, typically 0.5 MPa. This low nominal cleavage strength is due to stress concentration on a small part of the YBCO-coated conductor in cleavage fracture. Debonding by the cleavage stress occurs at the interface between the buffer layer and the Hastelloy substrate. The nominal cleavage strength for a slit edge of the conductor is 2.5-times lower than that for the original edge of the conductor; cracks and micro-peel existing over the slit edge reduce the cleavage strength for the slit edge. Cleavage stress and peel stress should be avoided in coil winding, as they easily delaminate the YBCO-coated conductor, resulting in substantial degradation of coil performance. These problems are especially important for epoxy impregnated YBCO-coated conductor coils. It appears that effect of cleavage stress and peel stress are mostly negligible for paraffin impregnated YBCO-coated conductor coils or dry wound YBCO-coated conductor coils.

  6. Concluding theoretical remarks

    International Nuclear Information System (INIS)

    Ellis, J.

    1986-01-01

    My task in this talk is to review the happenings of this workshop from a theoretical perspective, and to emphasize lines for possible future research. My remarks are organized into a theoretical overview of the what, why, (mainly the hierarchy problem) how, (supersymmetry must be broken: softly or spontaneously, and if the latter, by means of a new U tilde(1) gauge group or through the chiral superfields) when (how heavy are supersymmetric partner particles in different types of theories) and where (can one find evidence for) supersymmetry. In the last part are discussed various ongoing and future searches for photinos γ tilde, gravitinos G tilde, the U vector boson, shiggses H tilde, squarks q tilde and sleptons l tilde, gluinos g tilde, winos W tilde and other gauginos, as well as hunts for indirect effects of supersymmetry, such as for example in baryon decay. Finally there is a little message of encouragement to our experimental colleagues, based on historical precedent. (orig.)

  7. Remarkable support effect on the reactivity of Pt/In2O3/MOx catalysts for methanol steam reforming

    Science.gov (United States)

    Liu, Xin; Men, Yong; Wang, Jinguo; He, Rong; Wang, Yuanqiang

    2017-10-01

    Effects of supports over Pt/In2O3/MOx catalysts with extremely low loading of Pt (1 wt%) and In2O3 loadings (3 wt%) are investigated for the hydrogen production of methanol steam reforming (MSR) in the temperature range of 250-400 °C. Under practical conditions without the pre-reduction, the 1Pt/3In2O3/CeO2 catalyst shows the highly efficient catalytic performance, achieving almost complete methanol conversion (98.7%) and very low CO selectivity of 2.6% at 325 °C. The supported Pt/In2O3 catalysts are characterized by means of Brunauer-Emmett-Teller (BET) surface area, X-ray diffraction (XRD), high-resolution transmission microscopy (HRTEM), temperature programmed reduction with hydrogen (H2-TPR), CO pulse chemisorption, temperature programmed desorption of methanol and water (CH3OH-TPD and H2O-TPD). These demonstrate that the nature of catalyst support of Pt/In2O3/MOx plays crucial roles in the Pt dispersion associated by the strong interaction among Pt, In2O3 and supporting materials and the surface redox properties at low temperature, and thus affects their capability to activate the reactants and determines the catalytic activity of methanol steam reforming. The superior 1Pt/3In2O3/CeO2 catalyst, exhibiting a remarkable reactivity and stability for 32 h on stream, demonstrates its potential for efficient hydrogen production of methanol steam reforming in mobile and de-centralized H2-fueled PEMFC systems.

  8. NRC closing remarks

    International Nuclear Information System (INIS)

    Coffman, F.

    1994-01-01

    This section contains the edited transcript of the NRC closing remarks made by Mr. Franklin Coffman (Chief, Human Factors Branch, Office of Nuclear Regulatory Research) and Dr. Cecil Thomas (Deputy Director, Division of Reactor Controls and Human Factors, Office of Nuclear Reactor Regulation). This editing consisted of minimal editing to correct grammar and remove extraneous references to microphone volume, etc

  9. Remarks of Joseph Marrone

    International Nuclear Information System (INIS)

    Marrone, J.

    1985-01-01

    The author's remarks are directed primarily at proposals that have been made that would substantially tort law with respect to radiation claims in order to ease the ability of claimants to recovery damages from defendants. The change would be based upon what had been assumed to be a ''scientific'' means of measuring the ''probability'' that exposure to ionizing radiation was the case of a cancer in a particular claimant. The remarks are divided into three parts: a summary description of the nuclear insurance pools, including the tort radiation claims filed against the pools; and a brief description of claims against the Federal Government and its contractors; an examination of the elementary principles of tort law, and an outline of the threat that has developed that would transform it into a hybrid social benefits program; and comment on the danger to the integrity of science when it is injected into the legislative process

  10. Remarks on stellar clusters

    International Nuclear Information System (INIS)

    Teller, E.

    1985-01-01

    In the following, a few simple remarks on the evolution and properties of stellar clusters will be collected. In particular, globular clusters will be considered. Though details of such clusters are often not known, a few questions can be clarified with the help of primitive arguments. These are:- why are spherical clusters spherical, why do they have high densities, why do they consist of approximately a million stars, how may a black hole of great mass form within them, may they be the origin of gamma-ray bursts, may their invisible remnants account for the missing mass of our galaxy. The available data do not warrant a detailed evaluation. However, it is remarkable that exceedingly simple models can shed some light on the questions enumerated above. (author)

  11. Remarks on High Energy Evolution

    OpenAIRE

    Kovner, Alex; Lublinsky, Michael

    2005-01-01

    We make several remarks on the B-JIMWLK hierarchy. First, we present a simple and instructive derivation of this equation by considering an arbitrary projectile wave function with small number of valence gluons. We also generalize the equation by including corrections which incorporate effects of high density in the projectile wave function. Second, we systematically derive the dipole model approximation to the hierarchy. We show that in the dipole approximation the hierarchy has a simplifyin...

  12. Seven remarkable days

    CERN Document Server

    This has been a truly remarkable seven days for CERN. Things have moved so fast that it has sometimes been hard to separate fact from fiction – all the more so since facts have often seemed too good to be true. It’s been a week of many firsts. Monday was the first time we’ve had two captured beams in the LHC. It’s the first time the LHC has functioned as a particle accelerator, boosting particles to the highest beam energy so far achieved at CERN. And it’s been a week in which we’ve seen the highest energy proton-proton collisions ever produced at CERN: our last hadron collider, the SPS was a proton-antiproton collider, a technically simpler machine than the LHC. This week’s successes are all the more remarkable precisely because of the complexity of the LHC. Unlike the SPS collider, it is two accelerators not one, making the job of commissioning nearly twice as difficult. I’d like to express my heartfelt thanks and congra...

  13. Remarkable resilience of teeth.

    Science.gov (United States)

    Chai, Herzl; Lee, James J-W; Constantino, Paul J; Lucas, Peter W; Lawn, Brian R

    2009-05-05

    Tooth enamel is inherently weak, with fracture toughness comparable with glass, yet it is remarkably resilient, surviving millions of functional contacts over a lifetime. We propose a microstructural mechanism of damage resistance, based on observations from ex situ loading of human and sea otter molars (teeth with strikingly similar structural features). Section views of the enamel implicate tufts, hypomineralized crack-like defects at the enamel-dentin junction, as primary fracture sources. We report a stabilization in the evolution of these defects, by "stress shielding" from neighbors, by inhibition of ensuing crack extension from prism interweaving (decussation), and by self-healing. These factors, coupled with the capacity of the tooth configuration to limit the generation of tensile stresses in largely compressive biting, explain how teeth may absorb considerable damage over time without catastrophic failure, an outcome with strong implications concerning the adaptation of animal species to diet.

  14. Are there any remarkable effects of prenatal exposure to food colourings on neurobehaviour and learning process in rat offspring?

    Science.gov (United States)

    Doguc, Duygu Kumbul; Aylak, Firdevs; Ilhan, Ilter; Kulac, Esin; Gultekin, Fatih

    2015-01-01

    Artificial food colourings and additives (AFCAs) have long been discussed to have adverse effects on cognition and behaviour in children. In this study, our aim was to assess the probable side effects of prenatal exposure to colouring food additives on neurobehaviour and spatial learning process. We administered 'no observable adverse effect levels' (NOAELs) of common used AFCAs as a mixture (erythrosine, Ponceau 4R, Allura Red AC, Sunset yellow FCF, tartrazine, Amaranth, Brilliant Blue, Azorubine and Indigotine) to female rats before and during gestation and tested their effects on spatial working memory and behaviour in their offspring. Effects of AFCAs on spatial working memory were evaluated by Morris water maze, behavioural and locomotor effects by open-field and forced-swim tests. Prenatal exposure to commonly used AFCAs had no adverse effects on spatial working memory; however, assessment of interaction of sex and AFCAs on 'latency to locate the visible platform', which was used as a measure of motivation, showed a significant interaction (P < 0.05) on female rats. In addition, AFCAs caused an increase in anxiolytic like effect in the open-field test (P < 0.05) and an increase in mobility time (P < 0.05) in the forced-swim test. We also detected a significant interaction of sex and AFCAs on forced-swim test parameters (P < 0.05). These findings indicated that prenatal exposure to NOAELs of AFCAs resulted in implicit adverse effects that caused an increase in motility and a decrease in motivation and anxiety in offspring in sex-related manner.

  15. Some remarks on the use of the effective medium approximation for the resistivity calculations in liquid noble metals

    International Nuclear Information System (INIS)

    Gorecki, J.

    1982-09-01

    The application of the effective medium approximation (EMA) to the muffin-tin model of liquid metal is considered. The triple correlation function is included in the expression for electrical resistivity. Good agreement with experimental data can be expected for liquid noble metals. (author)

  16. Observation of a remarkable reduction of correlation effects in BaCr2As2 by ARPES.

    Science.gov (United States)

    Nayak, Jayita; Filsinger, Kai; Fecher, Gerhard H; Chadov, Stanislav; Minár, Ján; Rienks, Emile D L; Büchner, Bernd; Parkin, Stuart P; Fink, Jörg; Felser, Claudia

    2017-11-21

    The superconducting phase in iron-based high-[Formula: see text] superconductors (FeSC), as in other unconventional superconductors such as the cuprates, neighbors a magnetically ordered one in the phase diagram. This proximity hints at the importance of electron correlation effects in these materials, and Hund's exchange interaction has been suggested to be the dominant correlation effect in FeSCs because of their multiband nature. By this reasoning, correlation should be strongest for materials closest to a half-filled [Formula: see text] electron shell (Mn compounds, hole-doped FeSCs) and decrease for systems with both higher (electron-doped FeSCs) and lower (Cr-pnictides) [Formula: see text] counts. Here we address the strength of correlation effects in nonsuperconducting antiferromagnetic BaCr 2 As 2 by means of angle-resolved photoemission spectroscopy (ARPES) and first-principles calculations. This combination provides us with two handles on the strength of correlation: First, a comparison of the experimental and calculated effective masses yields the correlation-induced mass renormalization. In addition, the lifetime broadening of the experimentally observed dispersions provides another measure of the correlation strength. Both approaches reveal a reduction of electron correlation in BaCr 2 As 2 with respect to systems with a [Formula: see text] count closer to five. Our results thereby support the theoretical predictions that Hund's exchange interaction is important in these materials.

  17. Some remarks about the effects of acceleration on time dilation in experiments with a Mössbauer source

    Science.gov (United States)

    Benedetto, E.; Feoli, A.

    2018-02-01

    We suggest an alternative interpretation of the experimental results obtained studying the circular accelerated motion of a rotor that plays the role of an absorber of photons emitted by a Mössbauer source. A spectral shift was discovered and interpreted in the light of a generalized relativistic theory with maximal acceleration. Alternatively we propose that the shift could be explained by a time-dependent Doppler effect in standard relativity.

  18. Remarkable activity of nitrogen-doped hollow carbon spheres encapsulated Cu on synthesis of dimethyl carbonate: Role of effective nitrogen

    Science.gov (United States)

    Li, Haixia; Zhao, Jinxian; Shi, Ruina; Hao, Panpan; Liu, Shusen; Li, Zhong; Ren, Jun

    2018-04-01

    A critical aspect in the improvement of the catalytic performance of Cu-based catalysts for the synthesis of dimethyl carbonate (DMC) is the development of an appropriate support. In this work, nitrogen-doped hollow carbon spheres (NHCSs), with 240 nm average diameter, 17 nm shell thickness, uniform mesoporous structure and a specific surface area of 611 m2 g-1, were prepared via a two-step Stӧber method. By varying the quantity of nitrogen-containing phenols used in the preparation it has been possible to control the nitrogen content and, consequently, the sphericity of the NHCSs. It was found that perfect spheres were obtained for nitrogen contents below 5.4 wt.%. The catalysts (Cu@NHCSs) were prepared by the hydrothermal impregnation method. The catalytic activity towards DMC synthesis was notably enhanced due to the immobilization effect on Cu particles and the enhanced electron transfer effect exercised by the effective nitrogen species, including pyridinic-N and graphitic-N. When the average size of the copper nanoparticles was 7.4 nm and the nitrogen content was 4.0 wt.%, the values of space-time yield of DMC and of turnover frequency (TOF) reached 1528 mg/(g h) and 11.0 h-1, respectively. The TOF value of Cu@NHCSs was 6 times higher than non-doped Cu@Carbon (2.1 h-1). The present work introduces the potential application of nitrogen-doped carbon materials and presents a novel procedure for the preparation of catalysts for DMC synthesis.

  19. Ecological tax reform - an optimal solution?. Critical remarks on the DIW study ''Economic effects of an ecological tax reform''

    International Nuclear Information System (INIS)

    Boehringer, C.; Fahl, H.; Voss, A.

    1994-01-01

    Through the latest expertise of the German institute for economic research (DIW) regarding an ecological tax reform, the discussion about a tax system considering the shortage of the ressource environment and a deficiency of demand regarding the ressource work is newly provoked. The focus of this article is a critical dealing with the methodical procedure of the German institute for economic reserarch when analyzing the national economic effect of a concretely formulated ecological tax law scenario. When assessing the overall economic consequences of a tax reform, it is recommended to use an analysis instrument, which is farly more consistent compared to the instruments by DIW, and which is more problem adequate through the increased resort to financial knowledge. Based on the obvious weakness of the DIW study, a more extensive comprehension for an ecological tax reform is pleaded for, standing out for an application of taxes based on division of labour and oriented to the objective. (orig./UA) [de

  20. Remarkable promotion effect of trace sulfation on OMS-2 nanorod catalysts for the catalytic combustion of ethanol.

    Science.gov (United States)

    Zhang, Jie; Zhang, Changbin; He, Hong

    2015-09-01

    OMS-2 nanorod catalysts were synthesized by a hydrothermal redox reaction method using MnSO4 (OMS-2-SO4) and Mn(CH3COO)2 (OMS-2-AC) as precursors. SO4(2-)-doped OMS-2-AC catalysts with different SO4(2-) concentrations were prepared next by adding (NH4)2SO4 solution into OMS-2-AC samples to investigate the effect of the anion SO4(2-) on the OMS-2-AC catalyst. All catalysts were then tested for the catalytic oxidation of ethanol. The OMS-2-SO4 catalyst synthesized demonstrated much better activity than OMS-2-AC. The SO4(2-) doping greatly influenced the activity of the OMS-2-AC catalyst, with a dramatic promotion of activity for suitable concentration of SO4(2-) (SO4/catalyst=0.5% W/W). The samples were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), inductively coupled plasma optical emission spectroscopy (ICP-OES), NH3-TPD and H2-TPR techniques. The results showed that the presence of a suitable amount of SO4(2-) species in the OMS-2-AC catalyst could decrease the Mn-O bond strength and also enhance the lattice oxygen and acid site concentrations, which then effectively promoted the catalytic activity of OMS-2-AC toward ethanol oxidation. Thus it was confirmed that the better catalytic performance of OMS-2-SO4 compared to OMS-2-AC is due to the presence of some residual SO4(2-) species in OMS-2-SO4 samples. Copyright © 2015. Published by Elsevier B.V.

  1. Effective potentials from complex simulations: a potential-matching algorithm and remarks on coarse-grained potentials

    International Nuclear Information System (INIS)

    Toth, Gergely

    2007-01-01

    The projection of complex interactions onto simple distance-dependent or angle-dependent classical mechanical functions is a long-standing theoretical challenge in the field of computational sciences concerning biomolecules, colloids, aggregates and simple systems as well. The construction of an effective potential may be based on theoretical assumptions, on the application of fitting procedures on experimental data and on the simplification of complex molecular simulations. Recently, a force-matching method was elaborated to project the data of Car-Parrinello ab initio molecular dynamics simulations onto two-particle classical interactions (Izvekov et al 2004 J. Chem. Phys. 120 10896). We have developed a potential-matching algorithm as a practical analogue of this force-matching method. The algorithm requires a large number of configurations (particle positions) and a single value of the potential energy for each configuration. We show the details of the algorithm and the test calculations on simple systems. The test calculation on water showed an example in which a similar structure was obtained for qualitatively different pair interactions. The application of the algorithm on reverse Monte Carlo configurations was tried as well. We detected inconsistencies in a part of our calculations. We found that the coarse graining of potentials cannot be performed perfectly both for the structural and the thermodynamic data. For example, if one applies an inverse method with an input of the pair-correlation function, it provides energetics data for the configurations uniquely. These energetics data can be different from the desired ones obtained by all atom simulations, as occurred in the testing of our potential-matching method

  2. Edward F. Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries

    Science.gov (United States)

    2014-01-01

    Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in modern societies, and advancing age is the major risk factor for CVD. Arterial dysfunction, characterized by large elastic artery stiffening and endothelial dysfunction, is the key event leading to age-associated CVD. Our work shows that regular aerobic exercise inhibits large elastic artery stiffening with aging (optimizes arterial compliance) and preserves endothelial function. Importantly, among previously sedentary late middle-aged and older adults, aerobic exercise improves arterial stiffness and enhances endothelial function in most groups and, therefore, also can be considered a treatment for age-associated arterial dysfunction. The mechanisms by which regular aerobic exercise destiffens large elastic arteries are incompletely understood, but existing evidence suggests that reductions in oxidative stress associated with decreases in both adventitial collagen (fibrosis) and advanced glycation end-products (structural protein cross-linking molecules), play a key role. Aerobic exercise preserves endothelial function with aging by maintaining nitric oxide bioavailability via suppression of excessive superoxide-associated oxidative stress, and by inhibiting the development of chronic low-grade vascular inflammation. Recent work from our laboratory supports the novel hypothesis that aerobic exercise may exert these beneficial effects by directly inducing protection to aging arteries against multiple adverse factors to which they are chronically exposed. Regular aerobic exercise should be viewed as a “first line” strategy for prevention and treatment of arterial aging and a vital component of a contemporary public health approach for reducing the projected increase in population CVD burden. PMID:24855137

  3. Edward F. Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries.

    Science.gov (United States)

    Seals, Douglas R

    2014-09-01

    Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in modern societies, and advancing age is the major risk factor for CVD. Arterial dysfunction, characterized by large elastic artery stiffening and endothelial dysfunction, is the key event leading to age-associated CVD. Our work shows that regular aerobic exercise inhibits large elastic artery stiffening with aging (optimizes arterial compliance) and preserves endothelial function. Importantly, among previously sedentary late middle-aged and older adults, aerobic exercise improves arterial stiffness and enhances endothelial function in most groups and, therefore, also can be considered a treatment for age-associated arterial dysfunction. The mechanisms by which regular aerobic exercise destiffens large elastic arteries are incompletely understood, but existing evidence suggests that reductions in oxidative stress associated with decreases in both adventitial collagen (fibrosis) and advanced glycation end-products (structural protein cross-linking molecules), play a key role. Aerobic exercise preserves endothelial function with aging by maintaining nitric oxide bioavailability via suppression of excessive superoxide-associated oxidative stress, and by inhibiting the development of chronic low-grade vascular inflammation. Recent work from our laboratory supports the novel hypothesis that aerobic exercise may exert these beneficial effects by directly inducing protection to aging arteries against multiple adverse factors to which they are chronically exposed. Regular aerobic exercise should be viewed as a "first line" strategy for prevention and treatment of arterial aging and a vital component of a contemporary public health approach for reducing the projected increase in population CVD burden. Copyright © 2014 the American Physiological Society.

  4. Summary and concluding remarks

    International Nuclear Information System (INIS)

    Vogt, E.

    1989-11-01

    Although most talks and discussions at the Bad Honnef conference were devoted to the science of the KAON Factory, it is the prospect of the imminent emergence of Canada's KAON Factory that evoked this meeting. Because of the many different kinds of beams provided by KAON, it will offer science opportunities pertinent to many of the current important issues. These include strong interaction physics problems such as hadron spectroscopy, hypernuclei, K + -nucleus scattering, and spin effects in N N scattering; antiproton physics issues; and electroweak physics issues involving tests of the standard model. It is expected that the cost of KAON will be shared among the governments of Canada and other participating countries

  5. Closing remarks: astronomical

    International Nuclear Information System (INIS)

    Pecker, J.-C.

    1990-01-01

    During the discussions we have covered many facets of the basic interactions between solar activity and the Earth's climate. Solar activity is not the only astronomical or astrophysical phenomenon to influence physical conditions in the biosphere. Over timescales an order of magnitude less, the location of the Solar System in the Galaxy may have influenced life on Earth. The Sun is a complex generator of radiation, particles and magnetic fields sent far into space. Even if the total radiation emitted is constant, the amount of radiation received by the Earth changes with time: this change is complex and involved with a redistribution of energy emitted at different solar latitudes than to a real change in solar luminosity. These changes in the Earth's illumination may be a function of the wavelength, and have various effects in different layers of the Earth's atmosphere. The Sun also emits particles of all energies. Some of them find their way through the magnetopause, giving rise to auroras, to magnetic storms, to ionospheric disturbances and the like. The possible climatological effects are yet obscure. To understand the solar terrestrial relations better, regular, routine observations from ground-based stations and from space of solar phenomena must be continued. The sensitivity of human life to small changes in climatic conditions is very large. A good knowledge of solar-physics is therefore important and relevant. (author)

  6. Closing Remarks and Awards

    International Nuclear Information System (INIS)

    Whitaker, M.; Van der Meer, K.; Hamilton, A.

    2015-01-01

    M. Whitaker: On behalf of the Institute of Nuclear Materials Management, we are grateful for the opportunity to support this symposium. The number of symposium events-presentations, posters, technical demonstrations, panel discussions, and receptions - has been completely overwhelming and truly impressive. My compliments to the IAEA organization staff for a spectacular event. I have gained a much better appreciation for why these are only once every four years. This symposium has provided an important opportunity to reengage with friends and colleagues from around the globe to discuss international safeguards topics. The theme this year is very appropriate. So much of our work relies upon people. Together we work to develop the strategies that ensure that international safeguards are effectively implemented to provide the world the assurances that they expect from us. Thank you for this opportunity to share in the organization and execution of this symposium. K. Van der Meer: It is my pleasure to give the last poster awards. We have had two award ceremonies already this week on Wednesday and Thursday to recognize the best posters in those sessions. Today it will be two parts. First we will give the award for the best posters for this morning's sessions, and then we have four special awards: Gold, Silver, Bronze and the New Generation Symposium Award. These are the awards for the best posters for the whole week. The New Generation Symposium Award is for recognition of a younger participant and the prize is also for a younger participant. The full list of award winners is available under the symposium website. The IAEA recognizes the generous donations by INMM and ESARDA of the following prizes given as awards for the best posters: · Best e-poster advertisement per session: free subscription to the ESARDA Bulletin; · Best e-poster per session: free membership in INMM; · Best poster of the week ''Bronze'': free registration for the 8th INMM

  7. Euclidean distance can identify the mannitol level that produces the most remarkable integral effect on sugarcane micropropagation in temporary immersion bioreactors.

    Science.gov (United States)

    Gómez, Daviel; Hernández, L Ázaro; Yabor, Lourdes; Beemster, Gerrit T S; Tebbe, Christoph C; Papenbrock, Jutta; Lorenzo, José Carlos

    2018-03-15

    Plant scientists usually record several indicators in their abiotic factor experiments. The common statistical management involves univariate analyses. Such analyses generally create a split picture of the effects of experimental treatments since each indicator is addressed independently. The Euclidean distance combined with the information of the control treatment could have potential as an integrating indicator. The Euclidean distance has demonstrated its usefulness in many scientific fields but, as far as we know, it has not yet been employed for plant experimental analyses. To exemplify the use of the Euclidean distance in this field, we performed an experiment focused on the effects of mannitol on sugarcane micropropagation in temporary immersion bioreactors. Five mannitol concentrations were compared: 0, 50, 100, 150 and 200 mM. As dependent variables we recorded shoot multiplication rate, fresh weight, and levels of aldehydes, chlorophylls, carotenoids and phenolics. The statistical protocol which we then carried out integrated all dependent variables to easily identify the mannitol concentration that produced the most remarkable integral effect. Results provided by the Euclidean distance demonstrate a gradually increasing distance from the control in function of increasing mannitol concentrations. 200 mM mannitol caused the most significant alteration of sugarcane biochemistry and physiology under the experimental conditions described here. This treatment showed the longest statistically significant Euclidean distance to the control treatment (2.38). In contrast, 50 and 100 mM mannitol showed the lowest Euclidean distances (0.61 and 0.84, respectively) and thus poor integrated effects of mannitol. The analysis shown here indicates that the use of the Euclidean distance can contribute to establishing a more integrated evaluation of the contrasting mannitol treatments.

  8. Effective Suckling C57BL/6, Kunming, and BALB/c Mouse Models with Remarkable Neurological Manifestation for Zika Virus Infection

    Science.gov (United States)

    Liu, Xuling; Ke, Changwen; Wu, Qinghua; Lu, Weizhi; Qin, Zhiran; He, Xiaoen; Liu, Yujing; Deng, Jieli; Xu, Suiqi; Li, Ying; Zhu, Li; Wan, Chengsong; Xiao, Weiwei; Xie, Qian; Zhang, Bao; Zhao, Wei

    2017-01-01

    Since 2015, 84 countries and territories reported evidence of vector-borne Zika Virus (ZIKV) transmission. The World Health Organization (WHO) declared that ZIKV and associated consequences especially the neurological autoimmune disorder Guillain–Barré syndrome (GBS) and microcephaly will remain a significant enduring public health challenge requiring intense action. We apply a standardization of the multi-subcutaneous dorsal inoculation method to systematically summarize clinical neurological manifestation, viral distribution, and tissue damage during the progress of viremia and systemic spread in suckling mouse models. We found that C57BL/6 and Kunming mice (KM) both showed remarkable and uniform neurologic manifestations. C57BL/6 owned the highest susceptibility and pathogenicity to the nervous system, referred to as movement disorders, with 100% incidence, while KM was an economic model for a Chinese study characterized by lower limb weakness with 62% morbidity. Slight yellow extraocular exudates were observed in BALB/c, suggesting the association with similar ocular findings to those of clinical cases. The virus distribution and pathological changes in the sera, brains, livers, kidneys, spleens, and testes during disease progression had strong regularity and uniformity, demonstrating the effectiveness and plasticity of the animal models. The successful establishment of these animal models will be conducive to expound the pathogenic mechanism of GBS. PMID:28661429

  9. Concluding Remarks | Ewing | Rwanda Journal

    African Journals Online (AJOL)

    Rwanda Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 2, No 2 (2015) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Concluding Remarks. Helen Ewing. Abstract. No Abstract. Full Text:.

  10. Remarks on the clump theory

    International Nuclear Information System (INIS)

    Krommes, J.A.

    1986-07-01

    Further details are provided of a soon-to-be published dialog [Phys. Fluids 29 (July, 1986)] which discussed the role of the small scales in fluid clump theory. It is argued that the approximation of the clump lifetime which is compatible with exponentially rapid separation of adjacent orbits is inappropriate for the description of the dynamically important large scales. Various other remarks are made relating to the analytic treatment of strong drift-wave-like turbulence

  11. Remarks on the clump theory

    International Nuclear Information System (INIS)

    Krommes, J.A.

    1986-01-01

    Further details are provided of a recently published dialog [Phys. Fluids 29 (July, 1986)] which discussed the role of the small scales in fluid clump theory. It is argued that the approximation of the clump lifetime which is compatible with exponentially rapid separation of adjacent orbits is inappropriate for the description of the dynamically important large scales. Various other remarks are made relating to the analytic treatment of strong drift-wave-like turbulence. (author)

  12. Editorial - a remark you made

    Directory of Open Access Journals (Sweden)

    Yngve Nordkvelle

    2007-12-01

    Full Text Available ”A remark you made” is the title of a wonderful tune by the famous jazz-rock group “Weather Report”, issued on the influential “Heavy weather” LP some 30 years ago. In an age where planning and rationalizing is the main issue in most contexts, whether it’s a matter of studying, teaching, doing research or using a diet, “A remark you made” is a symbol of attending to the unplanned, unforeseen and often, unwanted. In most accounts on cognitive development one is overtly focused on the manageable, on the predictable and expected, and not so attentive to the opposite. “A remark you made” makes us think again and reconsider what might be of value, in what we otherwise might neglect. A remark made by Terry Anderson at a conference last year (2006 was rather telling. Anderson is the renown distance educator from Athabasca University, Alberta Canada, and editor of our fellow e-journal “The International Review of Research in Open and Distance Learning”. I recite it here totally from my own memory, and I have never approached him to have it verified, falsified or commented. That doesn’t matter in this context. Standing on the podium, he lowered his voice and asked if any Danes were present in the room. There weren’t! Then he explained that his argument might be presented differently with Danes present: “You see – Danes seem to think that learning alone is no longer possible!” That remark caused quite a good laugh, not the least because any comment – good or bad – about fellow Scandinavians generally is considered to be a good joke. But it was also a comment on how not only distance education, or open and flexible learning, but learning theory in general is driven by the sociocultural learning theory, - and according to Anderson, particularly so in Denmark! Our first contribution in this issue is about the theory of media theory developed by one of our editors: Lars Qvortrup. Lars is now the rector of the Danish

  13. Development of REI meetings (concluding remarks)

    International Nuclear Information System (INIS)

    Roessler, K.

    1988-01-01

    It is an honour and a pleasure to deliver the concluding remarks of this Fourth International Conference on Radiation Effects in Insulators. After commenting upon the present meeting, the genesis of REI conferences, their aims and position relative to related meetings in radiation and ion implantation research will be treated, particularly in order to inform new-comers. The development of the last four REI meetings will be discussed on the base of a statistical analysis. Some recommendations and an outlook of future trends will be given. (orig.)

  14. Some remarks on non-monotonic effects at low radiation intensities, on the problem of extrapolating doses between high and low intensities and on the problem of thresholds

    International Nuclear Information System (INIS)

    Delattre, P.

    1983-01-01

    On the basis of a general descriptive framework which takes into account the intensity factor and the time distribution of radiation, a detailed justification for which is to be found in earlier publications, the three fundamental problems mentioned in the title of this paper can be approached in a new way. If the biological effect e for a given dose D delivered at different radiation intensities phi is studied, we find that the curve e=f(phi) can exhibit non-monotonic shapes. This type of phenomenon is known in pharmacology and toxicology and may well exist also for low- or medium-intensity radiation effects. Extrapolation of the effects of a given dose between high and low radiation intensities phi is usually carried out by means of an empirical linear or linear-quadratic formulation. This procedure is insufficiently justified from a theoretical point of view. It is shown here that the effects can be written in the form e=k(phi)D and that the factor of proportionality k(phi) is a generally very complicated function of phi. Hence, the usual extrapolation procedures cannot deal with certain ranges of values of phi within which the effects observed at a given dose may be greater than when the dose is delivered at higher intensity. The problem of thresholds is actually far more difficult than the current literature on the subject would suggest. It is shown here, on the basis of considerations of qualitative dynamics, that several types of threshold must be defined, starting with a threshold for the radiation intensity phi. All these thresholds are interrelated hierarchically in fairly complex ways which must be studied case by case. These results show that it is illusory to attempt to define a universal notion of threshold in terms of dose. The conceptual framework used in the proposed approach proves also to be very illuminating for other studies in progress, particularly in the investigation of phenomena associated with ageing and carcinogenesis. (author)

  15. Experimental measurement at the seismic station Ostrava-Krásné Pole (OKC): preliminary results and remarks on site effect at the studied locality

    Czech Academy of Sciences Publication Activity Database

    Lednická, Markéta; Rušajová, Jana

    2016-01-01

    Roč. 13, č. 2 (2016), s. 137-147 ISSN 1214-9705 R&D Projects: GA MŠk LM2010008; GA ČR GP13-07027P Institutional support: RVO:68145535 Keywords : seismic station OKC * spectral ratio * site effect Subject RIV: JM - Building Engineering Impact factor: 0.699, year: 2016 https://www.irsm.cas.cz/index.php?page=acta_content_doi&id_cislo=17

  16. General Remarks about mossbauer spectroscopy

    International Nuclear Information System (INIS)

    Mirzababayev, R.M.

    2001-01-01

    More than forty years have passed since the discovery of Mossbauer effect; one of the most brilliant findings in modern physics. This effect proved itself to be the powerful tool in almost all disciplines of the natural sciences and technology. Its unique feature is that it gives the possibility to get the results which cannot be obtained by any other physical methods. Mossbauer effect has been used as a key to unlock some basic physical, chemical and biological phenomena, as a guide for finding the new ways of solving applied scientific and technical problems of electronics, metallurgy, civil engineering, and even fine arts and archaeology. Very few scientific techniques can claim entry into as many countries as Mossbauer spectroscopy. Due to its wide application in an education and research processes the community of Mossbauer spectroscopists extends to almost 100 different countries. Laboratory equipment necessary for conducting gamma resonance spectroscopy, do not require large investments, premises, personnel. The spectrometer is rather small in size and could be installed on the ordinary laboratory table. That is why Mossbauer effect is widely used at numerous Universities all over the world as an universal instrument for tuition and research

  17. A remarkable synergistic effect at the transcriptomic level in peach fruits doubly infected by prunus necrotic ringspot virus and peach latent mosaic viroid.

    Science.gov (United States)

    Herranz, Mari Carmen; Niehl, Annette; Rosales, Marlene; Fiore, Nicola; Zamorano, Alan; Granell, Antonio; Pallas, Vicente

    2013-05-28

    Microarray profiling is a powerful technique to investigate expression changes of large amounts of genes in response to specific environmental conditions. The majority of the studies investigating gene expression changes in virus-infected plants are limited to interactions between a virus and a model host plant, which usually is Arabidopsis thaliana or Nicotiana benthamiana. In the present work, we performed microarray profiling to explore changes in the expression profile of field-grown Prunus persica (peach) originating from Chile upon single and double infection with Prunus necrotic ringspot virus (PNRSV) and Peach latent mosaic viroid (PLMVd), worldwide natural pathogens of peach trees. Upon single PLMVd or PNRSV infection, the number of statistically significant gene expression changes was relatively low. By contrast, doubly-infected fruits presented a high number of differentially regulated genes. Among these, down-regulated genes were prevalent. Functional categorization of the gene expression changes upon double PLMVd and PNRSV infection revealed protein modification and degradation as the functional category with the highest percentage of repressed genes whereas induced genes encoded mainly proteins related to phosphate, C-compound and carbohydrate metabolism and also protein modification. Overrepresentation analysis upon double infection with PLMVd and PNRSV revealed specific functional categories over- and underrepresented among the repressed genes indicating active counter-defense mechanisms of the pathogens during infection. Our results identify a novel synergistic effect of PLMVd and PNRSV on the transcriptome of peach fruits. We demonstrate that mixed infections, which occur frequently in field conditions, result in a more complex transcriptional response than that observed in single infections. Thus, our data demonstrate for the first time that the simultaneous infection of a viroid and a plant virus synergistically affect the host transcriptome in

  18. Theories of superconductivity (a few remarks)

    International Nuclear Information System (INIS)

    Ginzburg, V.L.

    1992-01-01

    The early history in the development of superconductivity. Idea of pairing, Schafroth and BCS types of theories. Some remarks on present state of the microscopical theory of high-temperature superconductors (HTSC). Mean field macroscopic theory of superconductivity and its specific features in HTSC. About generalized macroscopic theory applicable in critical region. Concluding remarks. (orig.)

  19. Introductory remarks of the Panellists

    International Nuclear Information System (INIS)

    Repacholi, R.

    2008-01-01

    It is important that local populations be informed of the Chernobyl Forum results, and this can be done very effectively through health care professionals, who tend to be trusted in the communities that they serve. They should therefore be provided with all the necessary information. As regards future research, the three Governments should cooperate closely with scientists around the world. The aim should be the study of a single large population group covering all three countries, with a single protocol so that we can maximize the statistical power and the sensitivity of the study

  20. Introductive remarks on causal inference

    Directory of Open Access Journals (Sweden)

    Silvana A. Romio

    2013-05-01

    Full Text Available One of the more challenging issues in epidemiological research is being able to provide an unbiased estimate of the causal exposure-disease effect, to assess the possible etiological mechanisms and the implication for public health. A major source of bias is confounding, which can spuriously create or mask the causal relationship. In the last ten years, methodological research has been developed to better de_ne the concept of causation in epidemiology and some important achievements have resulted in new statistical models. In this review, we aim to show how a technique the well known by statisticians, i.e. standardization, can be seen as a method to estimate causal e_ects, equivalent under certain conditions to the inverse probability treatment weight procedure.

  1. Concluding Remarks and Future Outlook

    Science.gov (United States)

    Durrani, S. A.; Ilić, R.

    Any reader who has perused the whole of this book with some care will, we believe, be struck by the great breadth and depth of the studies that have been, and are being, carried out on the whole gamut of radon research. These range from geological considerations and investigations that form the essential background to the causes and rates of emission of radon, through economically beneficial applications of the gas such as mineral exploration and search for geothermal energy sources, all the way to indoor and outdoor surveys of radon concentration levels, and critical appraisals of the health hazards of excessive exposure to radon and the measures that can be taken to minimize any deleterious effects - whether to the general public or to those working in mines and caves. And all through the book runs the unifying thread, linking its various parts: the theme-line of Solid State Nuclear Track Detection (SSNTD). This, as we stated in the Preface, is the technique that is most commonly used today for studying the many and various aspects of radon measurements and applications. Several sections of the book have, therefore, been devoted to giving the reader a broad background to the SSNTD discipline and also providing him or her with detailed descriptions of all the various types of instrumentation and devices (both "passive" and "active") used in applications ranging from simple determination of radon concentration levels in homes to earthquake prediction and volcanic surveillance - not to forget the important subject of calibration and standardization of the detectors…

  2. Concluding Remarks: Experiment from a materials perspective

    International Nuclear Information System (INIS)

    Fisk, Z

    2011-01-01

    The author provides some remarks regarding the current status of experiments in strongly correlated electron systems. By construction, they are biased by the author's perspectives at the time of writing.

  3. Remarks about the hypothesis of limiting fragmentation

    International Nuclear Information System (INIS)

    Chou, T.T.; Yang, C.N.

    1987-01-01

    Remarks are made about the hypothesis of limiting fragmentation. In particular, the concept of favored and disfavored fragment distribution is introduced. Also, a sum rule is proved leading to a useful quantity called energy-fragmentation fraction. (author). 11 refs, 1 fig., 2 tabs

  4. Remarkable adsorptive removal of nitrogen-containing compounds from a model fuel by a graphene oxide/MIL-101 composite through a combined effect of improved porosity and hydrogen bonding

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Imteaz; Jhung, Sung Hwa, E-mail: sung@knu.ac.kr

    2016-08-15

    Highlights: • Metal-organic frameworks (MIL-101) were composed with graphene oxide (GnO). • GnO/MIL-101 showed the highest adsorption capacity for indole and quinoline. • Adsorption mechanism was clearly shown based on adsorption results and FTIR. • GnO/MIL-101 might be applied commercially considering capacity and reusability. - Abstract: A composite was prepared by combining a highly porous metal-organic framework (MOF), MIL-101 (Cr-benzenedicarboxylate), and graphene oxide (GnO). The porosity of the composite increased appreciably by the addition of GnO up to a specific amount in the MOF, though further increases in the quantity of GnO was detrimental to porosity. The improved porosity of the GnO/MIL-101 composite was utilized for adsorptive denitrogenation (ADN) of a model fuel where indole (IND) and quinoline (QUI) were used as nitrogen-containing compounds (NCCs). It was found that both IND and QUI showed improved adsorption on the composite compared with pristine MIL-101 or GnO due to the improved porosity of the composite. Interestingly, the improvement in adsorption of IND was much higher than the quantity estimated for the porosity. Importantly, GnO/MIL-101 showed the highest adsorption capacities for NCCs. Irrespective of the studied solvents and co-presence of IND and QUI, the composite adsorbent performed ADN most effectively. This remarkable improvement is explained by the additional mechanism of hydrogen bonding between the surface functional groups of GnO and the hydrogen attached to the nitrogen atom of IND. This hydrogen bonding mechanism is also supported by the results of the adsorption of pyrrole and methylpyrrole. On the other hand, QUI does not show hydrogen-bonding capability, and therefore, its enhanced adsorption originates from only the increased porosity of the adsorbents.

  5. Remarkable adsorptive removal of nitrogen-containing compounds from a model fuel by a graphene oxide/MIL-101 composite through a combined effect of improved porosity and hydrogen bonding

    International Nuclear Information System (INIS)

    Ahmed, Imteaz; Jhung, Sung Hwa

    2016-01-01

    Highlights: • Metal-organic frameworks (MIL-101) were composed with graphene oxide (GnO). • GnO/MIL-101 showed the highest adsorption capacity for indole and quinoline. • Adsorption mechanism was clearly shown based on adsorption results and FTIR. • GnO/MIL-101 might be applied commercially considering capacity and reusability. - Abstract: A composite was prepared by combining a highly porous metal-organic framework (MOF), MIL-101 (Cr-benzenedicarboxylate), and graphene oxide (GnO). The porosity of the composite increased appreciably by the addition of GnO up to a specific amount in the MOF, though further increases in the quantity of GnO was detrimental to porosity. The improved porosity of the GnO/MIL-101 composite was utilized for adsorptive denitrogenation (ADN) of a model fuel where indole (IND) and quinoline (QUI) were used as nitrogen-containing compounds (NCCs). It was found that both IND and QUI showed improved adsorption on the composite compared with pristine MIL-101 or GnO due to the improved porosity of the composite. Interestingly, the improvement in adsorption of IND was much higher than the quantity estimated for the porosity. Importantly, GnO/MIL-101 showed the highest adsorption capacities for NCCs. Irrespective of the studied solvents and co-presence of IND and QUI, the composite adsorbent performed ADN most effectively. This remarkable improvement is explained by the additional mechanism of hydrogen bonding between the surface functional groups of GnO and the hydrogen attached to the nitrogen atom of IND. This hydrogen bonding mechanism is also supported by the results of the adsorption of pyrrole and methylpyrrole. On the other hand, QUI does not show hydrogen-bonding capability, and therefore, its enhanced adsorption originates from only the increased porosity of the adsorbents.

  6. Some concluding remarks about cold moderator development

    International Nuclear Information System (INIS)

    Carpenter, J.M.

    1990-01-01

    This paper is the transcription of remarks made at the conclusion of the Workshop on Cold Neutron Sources held at the Los Angeles National Laboratory, Los Alamos, New Mexico, March 5--7, 1990. Areas of interest include the following: scattering functions; cold moderator materials; radiation mixing of chemical composition; comparison of some pulsed moderator spectra; hydrogen mixtures; premoderators and shields; composite reflectors; exotic moderator materials; deuterated methanes; mixed moderator materials; and test facility availabilities. 2 refs., 4 figs., 1 tab

  7. Some remarks on word formation in Danish

    DEFF Research Database (Denmark)

    Götzsche, Hans

    Abstract for the 25th Scandinavian Conference of Linguistics Some remarks on wordformation in Danish Some Danish word formation phenomena pose a problem for the linguist, being a predicament for analysis. In Danish a train leaves the station when it afgår ‘leaves’, while a minister may gå af......, there are some patterns for these Danish compounds concerning their internal semantics, in that the same lexical items may be used for different purposes depending on whether they are formed as a straightforward linear sequence (a word formation) or a reversed sequence (a phrase). The problem is (i) how the two...

  8. Some Remarks on Stability of Generalized Equations

    Czech Academy of Sciences Publication Activity Database

    Outrata, Jiří; Henrion, R.; Kruger, A.Y.

    2013-01-01

    Roč. 159, č. 3 (2013), s. 681-697 ISSN 0022-3239 R&D Projects: GA AV ČR IAA100750802; GA ČR(CZ) GAP201/12/0671 Institutional support: RVO:67985556 Keywords : Parameterized generalized equation * Regular and limiting coderivative * Constant rank CQ * Mathematical program with equilibrium constraints Subject RIV: BA - General Mathematics Impact factor: 1.406, year: 2013 http://library.utia.cas.cz/separaty/2013/MTR/outrata-some remarks on stability of generalized equations.pdf

  9. Chandra Sees Remarkable Eclipse of Black Hole

    Science.gov (United States)

    2007-04-01

    A remarkable eclipse of a supermassive black hole and the hot gas disk around it has been observed with NASA's Chandra X-ray Observatory. This eclipse has allowed two key predictions about the effects of supermassive black holes to be tested. Just as eclipses of the Sun and moon give astronomers rare opportunities to learn about those objects, an alignment in a nearby galaxy has provided a rare opportunity to investigate a supermassive black hole. Illustrations of Black Hole Eclipse Illustrations of Black Hole Eclipse The supermassive black hole is located in NGC 1365, a galaxy 60 million light years from Earth. It contains a so called active galactic nucleus, or AGN. Scientists believe that the black hole at the center of the AGN is fed by a steady stream of material, presumably in the form of a disk. Material just about to fall into a black hole should be heated to millions of degrees before passing over the event horizon, or point of no return. The disk of gas around the central black hole in NGC 1365 produces copious X-rays but is much too small to resolve directly with a telescope. However, the disk was eclipsed by an intervening cloud, so observation of the time taken for the disk to go in and out of eclipse allowed scientists to estimate the size of the disk. Black Hole Animation Black Hole Animation "For years we've been struggling to confirm the size of this X-ray structure," said Guido Risaliti of the Harvard-Smithsonian Center for Astrophysics (CfA) in Cambridge, Mass, and the Italian Institute of Astronomy (INAF). "This serendipitous eclipse enabled us to make this breakthrough." The Chandra team directly measured the size of the X-ray source as about seven times the distance between the Sun and the Earth. That means the source of X-rays is about 2 billion times smaller than the host galaxy and only about 10 times larger than the estimated size of the black hole's event horizon, consistent with theoretical predictions. Chandra X-ray Image of NGC 1365

  10. Chemical physics of electroactive materials: concluding remarks.

    Science.gov (United States)

    Rutland, Mark W

    2017-07-01

    It is an honour to be charged with providing the concluding remarks for a Faraday Discussion. As many have remarked before, it is nonetheless a prodigious task, and what follows is necessarily a personal, and probably perverse, view of a watershed event in the Chemical Physics of Electroactive materials. The spirit of the conference was captured in a single sentence during the meeting itself."It is the nexus between rheology, electrochemistry, colloid science and energy storage". The current scientific climate is increasingly dominated by a limited number of global challenges, and there is thus a tendency for research to resemble a football match played by 6 year olds, where everyone on the field chases the (funding) ball instead of playing to their "discipline". It is thus reassuring to see how the application of rigorous chemical physics is leading to ingenious new solutions for both energy storage and harvesting, via, for example, nanoactuation, electrowetting, ionic materials and nanoplasmonics. In fact, the same language of chemical physics allows seamless transition between applications as diverse as mechano-electric energy generation, active moisture transport and plasmonic shutters - even the origins of life were addressed in the context of electro-autocatalysis!

  11. Remarks about the displaced spectra techniques

    International Nuclear Information System (INIS)

    Behringer, K.; Pineyro, J.

    1989-01-01

    In a recent paper a new method, called displaced spectra techniques, was presented for distinguishing between sinusoidal components and narrowband random noise contributions in otherwise random noise data. It is based on Fourier transform techniques, and uses the power spectral density (PSD) and a newly-introduced second-order displaced power spectra density (SDPSD) function. In order to distinguish between the two peak types, a validation criterion has been established. In this note, three topics are covered: a) improved numerical data for the validation criterion are given by using the refined estimation procedure of the PSD and SDPSD functions by the Welch method; b) the validation criterion requires the subtraction of the background below the peaks. A semiautomatic procedure is described; c) it was observed that peaks in the real part of the SDPSD function can be accompanied by fine structure phenomena which are unresolved in the PSD function. A few remarks are made about this problem. (author)

  12. The end of a remarkable era

    CERN Multimedia

    2011-01-01

    An important era in particle physics is coming to an end: the US Department of Energy announced on Monday that it will not fund an extension to Tevatron running beyond 2011. It is a poignant moment for particle physics as we prepare to bid farewell to a machine that has changed our view of the Universe, and played a significant role in paving the way for the new era that is opening up with the LHC.   The Tevatron has been at the high-energy frontier of particle physics for over a quarter of a century. That’s a remarkable achievement by any account, and the physics results are there to prove it. As well as bringing us the discovery of the top quark in 1995, the Tevatron’s experiments have provided vitally important precision measurements covering the full spectrum of Standard Model physics, not to mention hints of what may lie beyond. With several months of running still to come, it would be a foolish gambler who bet against further new physics emerging before the Teva...

  13. Remarks on theoretical hot-atom chemistry

    International Nuclear Information System (INIS)

    Inokuti, Mitio

    1993-01-01

    The publication of the 'Handbook of Hot Atom Chemistry', following the earlier volume 'Recent Trend and Application', was a major milestone in physical chemistry. Theoretical treatments of hot atom chemistry must address two classes of problems. The first class concerns the individual collisions of hot atoms with other atoms or molecules. The second class concerns the description of the consequences of the many collisions of hot atoms and their chemical environment. Most of the remarks pertain to the problems of the first class. The central issue is the adiabaticity of nuclear motions versus electronic motions. To be precise, any atomic core motion should be mentioned rather than pure nuclear motion, because tightly bound core electrons are largely irrelevant to the chemistry. When nuclear motions are sufficiently slow, or for other reasons that can be regarded as adiabatic, the collision problem is basically straightforward, therefore, interatomic and intermolecular forces can be assumed, and their consequences for nuclear motions are calculable in principle. In the case of non-adiabaticity being important, much more difficult problems arise, and it is briefly discussed, and the work by Phelps is cited. (K.I.)

  14. Single molecule microscopy and spectroscopy: concluding remarks.

    Science.gov (United States)

    van Hulst, Niek F

    2015-01-01

    Chemistry is all about molecules: control, synthesis, interaction and reaction of molecules. All too easily on a blackboard, one draws molecules, their structures and dynamics, to create an insightful picture. The dream is to see these molecules in reality. This is exactly what "Single Molecule Detection" provides: a look at molecules in action at ambient conditions; a breakthrough technology in chemistry, physics and biology. Within the realms of the Royal Society of Chemistry, the Faraday Discussion on "Single Molecule Microscopy and Spectroscopy" was a very appropriate topic for presentation, deliberation and debate. Undoubtedly, the Faraday Discussions have a splendid reputation in stimulating scientific debates along the traditions set by Michael Faraday. Interestingly, back in the 1830's, Faraday himself pursued an experiment that led to the idea that atoms in a compound were joined by an electrical component. He placed two opposite electrodes in a solution of water containing a dissolved compound, and observed that one of the elements of the compound accumulated on one electrode, while the other was deposited on the opposite electrode. Although Faraday was deeply opposed to atomism, he had to recognize that electrical forces were responsible for the joining of atoms. Probably a direct view on the atoms or molecules in his experiment would have convinced him. As such, Michael Faraday might have liked the gathering at Burlington House in September 2015 (). Surely, with the questioning eyes of his bust on the 1st floor corridor, the non-believer Michael Faraday has incited each passer-by to enter into discussion and search for deeper answers at the level of single molecules. In these concluding remarks, highlights of the presented papers and discussions are summarized, complemented by a conclusion on future perspectives.

  15. Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity.

    Science.gov (United States)

    Athanasiadis, Georgios; Cheng, Jade Y; Vilhjálmsson, Bjarni J; Jørgensen, Frank G; Als, Thomas D; Le Hellard, Stephanie; Espeseth, Thomas; Sullivan, Patrick F; Hultman, Christina M; Kjærgaard, Peter C; Schierup, Mikkel H; Mailund, Thomas

    2016-10-01

    Denmark has played a substantial role in the history of Northern Europe. Through a nationwide scientific outreach initiative, we collected genetic and anthropometrical data from ∼800 high school students and used them to elucidate the genetic makeup of the Danish population, as well as to assess polygenic predictions of phenotypic traits in adolescents. We observed remarkable homogeneity across different geographic regions, although we could still detect weak signals of genetic structure reflecting the history of the country. Denmark presented genomic affinity with primarily neighboring countries with overall resemblance of decreasing weight from Britain, Sweden, Norway, Germany, and France. A Polish admixture signal was detected in Zealand and Funen, and our date estimates coincided with historical evidence of Wend settlements in the south of Denmark. We also observed considerably diverse demographic histories among Scandinavian countries, with Denmark having the smallest current effective population size compared to Norway and Sweden. Finally, we found that polygenic prediction of self-reported adolescent height in the population was remarkably accurate (R 2 = 0.639 ± 0.015). The high homogeneity of the Danish population could render population structure a lesser concern for the upcoming large-scale gene-mapping studies in the country. Copyright © 2016 by the Genetics Society of America.

  16. Remarks to the hot channel power characteristics

    International Nuclear Information System (INIS)

    Tinka, I.; Tinkova, E.

    2002-01-01

    In connection with methodological improvements of safety analyses, some effects of detail power distributions, that should be taken into account for the hot channel characteristics determination, have been studied. This determination concerns the whole channel power (power of the fuel rod) and its axial (along the channel) and radial (across the fuel pellet radius) distribution. The total power of the channel is studied from the point of possible restrictions for different numbers of main cooling loops in operation. For radial power distribution the effect of burnup has been studied and for axial distribution the effect of the control rod vicinity (its coupler part) has been evaluated. The DNBR and fuel temperatures have been the key safety parameters influenced by these hot channel characteristics and have been evaluated in this study (Authors)

  17. Some remarks concerning relativistic kinetic theory

    International Nuclear Information System (INIS)

    Schroeter, J.

    1990-01-01

    The starting point of our investigation is a classical kinetic theory which includes correlational effects as well as the complete electromagnetic interaction. Also classical gravitation can be incorporated. The relativistic version of this theory is written down using some heuristic arguments. Its essential feature is the difference between terms representing gravitational interaction and the metric tensor representing geometrical properties. (author)

  18. Remarks on the Curci-Ferrari Model

    Science.gov (United States)

    Lavrov, Peter M.

    2012-07-01

    We study a dependence of Green's functions for the Curci-Ferrari model on the parameter resembling the gauge parameter in massless Yang-Mills theories. It is shown that the on-shell generating functional of vertex functions (effective action) depends on this parameter.

  19. Remark on natural models of neutrinos

    International Nuclear Information System (INIS)

    Fujikawa, Kazuo

    2005-01-01

    We comment on what 't Hooft's naturalness argument implies with regard to a minimal extension of the Standard Model that incorporates right-handed neutrinos with generic mass terms. If this Lagrangian is taken as that of a low energy effective theory, the idea of pseudo-Dirac neutrinos with very small masses is consistent with 't Hooft's naturalness argument. This argument is based on the observation that the right-handed components of neutrinos in the massless limit exhibit an extra enhanced symmetry which is absent in other charged fermions. This enhanced symmetry is reminiscent of the Nambu-Goldstone fermions associated with spontaneously broken supersymmetry. The conventional seesaw scenario gives another natural solution if the ultra-heavy right-handed neutrinos are integrated out in the formulation of a low energy effective theory. (author)

  20. Anticoagulant rodenticides and wildlife: Concluding remarks

    Science.gov (United States)

    van den Brink, Nico W.; Elliott, John E.; Shore, Richard F.; Rattner, Barnett A.

    2018-01-01

    Rodents are known to affect human society globally in various adverse ways, resulting in a widespread demand for their continuous control. Anticoagulant rodenticides (ARs) have been, and currently remain, the cornerstone of rodent control throughout the world. Although alternative control methods exist, they are generally less effective. ARs work by affecting vitamin K metabolism, thereby preventing the activation of blood clotting factors and eventual coagulopathy. Since ARs are non-selective, their undoubted benefits for rodent control have to be balanced against the environmental risks that these compounds pose. Although they have been used for decades, pharmacokinetic and toxicokinetic data are mainly available for laboratory mammals and have concentrated on acute effects. Limited information is available on chronic exposure scenarios and for wildlife species. Important gaps exist in our understanding of the large inter- and intra-species differences in sensitivity to ARs, especially for non-target species, and in our knowledge about the occurrence and importance of sub-lethal effects in wildlife. It is clear that mere presence of AR residues in the body tissues may not indicate the occurrence of effects, although unequivocal assessment of effects under field conditions is difficult. Ante-mortem symptoms, like lethargy, subdued behaviour and unresponsiveness are generally not very specific as is true for more generic post-mortem observations (e.g. pallor of the mucous membranes or occurrence of haemorrhages). It is only by combining ante or post-mortem data with information on exposure that effects in the field may be confirmed. We do know however that a wide variety of non-target species are directly exposed to ARs. Secondary exposure in predators is also widespread although there is limited information on whether this exposure causes actual effects. Exposure is driven by ecological factors and is context specific with respect to spatial habitat configuration

  1. Remarks on Chern-Simons Invariants

    Science.gov (United States)

    Cattaneo, Alberto S.; Mnëv, Pavel

    2010-02-01

    The perturbative Chern-Simons theory is studied in a finite-dimensional version or assuming that the propagator satisfies certain properties (as is the case, e.g., with the propagator defined by Axelrod and Singer). It turns out that the effective BV action is a function on cohomology (with shifted degrees) that solves the quantum master equation and is defined modulo certain canonical transformations that can be characterized completely. Out of it one obtains invariants.

  2. Remarks on transport theories of interplanetary fluctuations

    International Nuclear Information System (INIS)

    Ye Zhou; Matthaeus, W.H.

    1990-01-01

    The structure of approximate transport theories for the radial behavior of interplanetary fluctuations is reconsidered. The emphasis is on theories derived under the assumption of scale separation; i.e., the correlation length of the fluctuations is much less than the scale of large inhomogeneities. In these cases the zero-wavelength limit provides a first approximation to the spectral evolution equations for the radial dependence of interplanetary fluctuation spectra. The goal here is to investigate the structure of a recently presented (Zhou and Matthaeus, 1989) transport theory, in which coupling of inward- and outward-type fluctuations appears in the leading order, an effect the authors call mixing. In linear theory, mixing-type couplings of inward-type and outward-type waves are formally a nonresonant effect. However, leading order mixing terms do not vanish at zero wavelength for fluctuations that vary nearly perpendicular to the local magnetic field, or when the mean magnetic field is weak. Leading order mixing terms also survive when the dispersion relation fails and there is a nonunique relationship between frequency and wave number. The former case corresponds to nearly two-dimensional structures; these are included, for example, in isotropic models of turbulence. The latter instance occurs when wave-wave couplings are sufficiently strong. Thus there are a variety of situations in which leading order mixing effects are expected to be present

  3. Remark on the computation of mode sums

    International Nuclear Information System (INIS)

    Allen, Theodore J.; Olsson, M. G.; Schmidt, Jeffrey R.

    2000-01-01

    The computation of mode sums of the types encountered in basic quantum field theoretic applications is addressed with an emphasis on their expansions into functions of distance that can be interpreted as potentials. We show how to regularize and calculate the Casimir energy for the continuum Nambu-Goto string with massive ends as well as for the discrete Isgur-Paton non-relativistic string with massive ends. As an additional example, we examine the effect on the interquark potential of a constant Kalb-Ramond field strength interacting with a QCD string. (c) 2000 The American Physical Society

  4. Routine medicare and radiation exposure. Introductory remarks

    International Nuclear Information System (INIS)

    Hirata, Hideki; Saito, Tsutomu

    2013-01-01

    As an introduction of the title series, outlines of radiation in physics, chemistry, biochemistry, biological effect and protection are explained from the clinical doctors' aspect of routine medicare, and of radiation exposure in which people's interest is raised after the Fukushima Nuclear Power Plant Accident in 2011. For physics, ionizing effects of radiation are described in relation to its quantum energy transfer and its medical utilization like imaging and radiotherapy. Then mentioned in brief is the radiation from elements consisting of human body, cosmic ray and background radiation from the earth, with reference to natural and standardized limits of exposure doses. Radiations from 226 Rn and 40 K are explained as an instance of environmental natural sources together with the concepts of radioactive decay series/scheme, of internal exposure, of hazard like double strand break (DSB) and of medical use such as boron neutron capture therapy (BNCT). For an artifact radiation source, shown are fission products of 235 U by neutron, first yielded in 1945. Evidence of evolution in biochemical repair mechanisms of DSB is explained with a comparison of irradiated drosophila mutation where linear non-threshold (LNT) hypothesis is proposed, and human non-homologous end joining and homologous recombination. Historical process of occupational, medical, public exposures and their protection is finally described from the discovery of X-ray in 1895 to the first ICRP publication in 1958 via the A-bomb explosion in 1945. (T.T.)

  5. Remarks on entanglement entropy in string theory

    Science.gov (United States)

    Balasubramanian, Vijay; Parrikar, Onkar

    2018-03-01

    Entanglement entropy for spatial subregions is difficult to define in string theory because of the extended nature of strings. Here we propose a definition for bosonic open strings using the framework of string field theory. The key difference (compared to ordinary quantum field theory) is that the subregion is chosen inside a Cauchy surface in the "space of open string configurations." We first present a simple calculation of this entanglement entropy in free light-cone string field theory, ignoring subtleties related to the factorization of the Hilbert space. We reproduce the answer expected from an effective field theory point of view, namely a sum over the one-loop entanglement entropies corresponding to all the particle-excitations of the string, and further show that the full string theory regulates ultraviolet divergences in the entanglement entropy. We then revisit the question of factorization of the Hilbert space by analyzing the covariant phase-space associated with a subregion in Witten's covariant string field theory. We show that the pure gauge (i.e., BRST exact) modes in the string field become dynamical at the entanglement cut. Thus, a proper definition of the entropy must involve an extended Hilbert space, with new stringy edge modes localized at the entanglement cut.

  6. General remarks. Regional revitalization in Fukushima Prefecture

    International Nuclear Information System (INIS)

    Fujita, Reiko

    2015-01-01

    With a focus on the efforts of the Atomic Energy Society of Japan for the accident of TEPCO Fukushima Daiichi Nuclear Power Station, this paper introduces the movement of decommissioning and decontamination, as well as the efforts for regional revitalization. After the accident, the Atomic Energy Society of Japan performed information collection / analysis / evaluation, held a variety of symposiums, listened to the opinions of experts and knowledgeable persons in and out of Japan, discussed the measures for the accident, and expressed its opinions. The investigation committee academically summarized a wide variety of information about the accident, and published a report. In its accident investigation report, it analyzed the underlying factors of the accident, and proposed recommendations of 50 items. It has continued for an additional contribution to complete the decommissioning project. It is disseminating accurate and easy-to-understand information as the standpoints of residents as well as a nuclear expert. It dispatches specialists to 'Decontamination Information Plaza' to continuously carry out the decontamination advisory job. As part of regional revitalization, it has been implementing a support, such as the provision of counselling and accurate information for the decision-making on the returning-home of refugees. Its contents are as follows; (1) provision of information on the decontamination situation of each site, (2) consultation about the health effects of radiation, and (3) dispatch cooperation of lecturers for education of the staff of municipalities. (A.O.)

  7. Legislation and patients' rights: some necessary remarks.

    Science.gov (United States)

    Mujovic-Zornic, Hajrija

    2007-12-01

    The essence of a patient's rights and legislation framework requires an answer to the question on how legislation can work towards better defining, respecting, protecting and effectiveness of these rights. First, it is necessary to give a short introduction to patients' rights, their definition and different classifications. In the long list of human rights, patients' rights obviously take one of the very important places. Human life and health are the values, which, in comparison with all other human values, are considered as values of the highest rank. Patients' rights represent a legal expression of something, which every person basically and naturally expects from a doctor, medical staff, and from a health care system in general. The subject of the second part of this paper presents the intention, scope and conception of necessary legislation. How should it be considered - in a wider sense or as a special law? Some theoretical and practical questions regarding interaction between medical ethics regulation, confidentiality, and legislation are discussed as well. In the European context there are numerous examples of laws with the specific purpose of protecting patients' rights. Special attention and critical review will be paid to the situation of patients' rights in Serbia. The paper concludes with the point that the role of legislation is evidently important, but the traditional view should be replaced with a new one, due to the reason that modem health law puts the protection of patients' rights on a higher level. De lege lata, the whole system of health law in its diversity (civil, penal and administrative) is characterized by better understanding of rights, duties and legal relations, either through regulation or the protection of patients' rights.

  8. Geoethical remarks to sustainable development concepts

    Science.gov (United States)

    Nemec, Vaclav

    2013-04-01

    Various natural disasters with extremely destructive effects (earthquakes, tsunamis, landslides, extreme floods etc.) - resulting from or connected with unavoidable geodynamical processes in the Earth crust with their possible hierarchical periodicity - have been occurring in the geological history mostly in distant past times without any possibility to be registered in the memory of human kind. Many of substantial changes occur in liaison with climatic changes. Let us remember that the Earth crust is a superb archive of past climates which documents repeated periods of global warming and cooling throughout Earth's history as demonstrated in the latest International Geological Congresses (Oslo - 2008 and Brisbane - 2012). Present changes should be seen in the context of these billions of years of natural changes. Mostly only earth scientists (geologists of many specialities) are competent and responsible for progress in studying these phenomena in order to solve possible forecasting and prediction of future returns of considerable changes. They should be supported by all competent authorities and players in the market. - Geoethics as a new discipline at junction of earth sciences and ethics tries to emphasize various contexts of facing extraordinary intensive natural hazards and disasters. Numerous examples in the course of recent years can be presented in various parts of the world. Moreover fresh experiences give a serious warning that also some relatively "small" disasters may appear as dangerous in continental and global scales. Geoethical issues are to be preferentially applied for assuring a fair co-existence of mankind with the abiotic Nature and for trying to minimize potential damages with a high level of responsibility. From this point of view some oversimplified "sustainable development" ideas can finally appear as unsustainable because of not taking into consideration all possible unavoidable disasters caused exclusively by the processes in the Earth

  9. Opening Remarks: SciDAC 2007

    Science.gov (United States)

    Strayer, Michael

    2007-09-01

    superheated ionic gas in the ITER reactor as a result of an AORSA run on 22,500 processors that achieved over 87 trillion calculations per second (87 teraflops) which is 74% of the system's theoretical peak. Tomorrow, Argonne and IBM will announce that the first IBM Blue Gene/P, a 100 teraflop system, will be shipped to the Argonne Leadership Computing Facility later this fiscal year. By the end of FY2007 ASCR high performance and leadership computing resources will include the 114 teraflop IBM Blue Gene/P; a 102 teraflop Cray XT4 at NERSC and a 119 teraflop Cray XT system at Oak Ridge. Before ringing in the New Year, Oak Ridge will upgrade to 250 teraflops with the replacement of the dual core processors with quad core processors and Argonne will upgrade to between 250-500 teraflops, and next year, a petascale Cray Baker system is scheduled for delivery at Oak Ridge. The multidisciplinary teams in our SciDAC Centers for Enabling Technologies and our SciDAC Institutes must continue to work with our Scientific Application teams to overcome the barriers that prevent effective use of these new systems. These challenges include: the need for new algorithms as well as operating system and runtime software and tools which scale to parallel systems composed of hundreds of thousands processors; program development environments and tools which scale effectively and provide ease of use for developers and scientific end users; and visualization and data management systems that support moving, storing, analyzing, manipulating and visualizing multi-petabytes of scientific data and objects. The SciDAC Centers, located primarily at our DOE national laboratories will take the lead in ensuring that critical computer science and applied mathematics issues are addressed in a timely and comprehensive fashion and to address issues associated with research software lifecycle. In contrast, the SciDAC Institutes, which are university-led centers of excellence, will have more flexibility to pursue

  10. The role of the demand-duration curve in the evaluation of power station installation policies. Remarks on its effects on stations' utilization, generating capacity, load factor history and consumptions

    International Nuclear Information System (INIS)

    Graziani, G.; Maineri, M.; Zanantoni, C.

    1976-12-01

    The role of the load-duration curve in determining the installation policy for an electric power system, is examined. The effect of the priority order for the allocation of the power stations in the load-diagram is also discussed: in the model used here (program TOTEM) this priority is given as a function of type and age of the station. The significance of the load factor history for a power station as a function of its age is also discussed. It is suggested that such a curve be deduced as a result of strategy calculations made with TOTEM rather than assumping it as input data

  11. The remarkably high excitation planetary nebula GC 6537.

    Science.gov (United States)

    Aller, L H; Hung, S; Feibelman, W A

    1999-05-11

    NGC 6537 is an unusually high excitation point symmetric planetary nebula with a rich spectrum. Its kinematical structures are of special interest. We are here primarily concerned with the high resolution spectrum as revealed by the Hamilton echelle Spectrograph at Lick Observatory (resolution approximately 0.2 A) and supplemented by UV and near-UV data. These extensive data permit a determination of interstellar extinction, plasma diagnostics, and ionic concentrations. The photoionization models that have been used successfully for many planetary nebulae are not entirely satisfactory here. The plasma electron temperature of a photoionization model cannot much exceed 20,000 K, but plasma diagnostics show that regions emitting radiation of highly ionized atoms such as [NeIV] and [NeV] are much hotter, showing that shock excitation must be important, as suggested by the remarkable kinematics of this object. Hence, instead of employing a strict photoionization model, we are guided by the nebular diagnostics, which reveal how electron temperature varies with ionization potential and accommodates density effects. The predictions of the photoionization model may be useful in estimating ionization correction factor. In effect, we have estimated the chemical composition by using both photoionization and shock considerations.

  12. Some remarks on the statistical model of heavy ion collisions

    International Nuclear Information System (INIS)

    Koch, V.

    2003-01-01

    This contribution is an attempt to assess what can be learned from the remarkable success of this statistical model in describing ratios of particle abundances in ultra-relativistic heavy ion collisions

  13. Some remarks on a scenario of supersymmetry in quantum mechanics

    International Nuclear Information System (INIS)

    Jannussis, A.; Tsohantzis, I; Vavougios, D.

    1990-01-01

    Some remarks are given on a recent paper of Lahiri, Kumar Roy and Bagchi who have constructed a scenario of supersymmetry in quantum mechanics by imposing a structure on the raising and lowering operators

  14. Remarks on the elaboration of an English–Spanish ...

    African Journals Online (AJOL)

    Spanish word-combination dictionary examined here, some concluding remarks are made with regard to the educational implications of this kind of dictionary primarily aimed at intermediate- to advanced-level Spanish-speaking EFL learners.

  15. A polyethylenimine-modified carboxyl-poly(styrene/acrylamide copolymer nanosphere for co-delivering of CpG and TGF-β receptor I inhibitor with remarkable additive tumor regression effect against liver cancer in mice

    Directory of Open Access Journals (Sweden)

    Liang SY

    2016-12-01

    Full Text Available Shuyan Liang,* Jun Hu,* Yuanyuan Xie, Qing Zhou, Yanhong Zhu, Xiangliang Yang National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, People’s Republic of China *These authors contributed equally to this work Abstract: Cancer immunotherapy based on nanodelivery systems has shown potential for treatment of various malignancies, owing to the benefits of tumor targeting of nanoparticles. However, induction of a potent T-cell immune response against tumors still remains a challenge. In this study, polyethylenimine-modified carboxyl-styrene/acrylamide (PS copolymer nanospheres were developed as a delivery system of unmethylated cytosine-phosphate-guanine (CpG oligodeoxynucleotides and transforming growth factor-beta (TGF-β receptor I inhibitors for cancer immunotherapy. TGF-β receptor I inhibitors (LY2157299, LY were encapsulated to the PS via hydrophobic interaction, while CpG oligodeoxynucleotides were loaded onto the PS through electrostatic interaction. Compared to the control group, tumor inhibition in the PS-LY/CpG group was up to 99.7% without noticeable toxicity. The tumor regression may be attributed to T-cell activation and amplification in mouse models. The results highlight the additive effect of CpG and TGF-β receptor I inhibitors co-delivered in cancer immunotherapy. Keywords: CpG, TGF-β receptor I inhibitor, Pst-AAm copolymer nanosphere, immunotherapy

  16. Directional selection in temporally replicated studies is remarkably consistent.

    Science.gov (United States)

    Morrissey, Michael B; Hadfield, Jarrod D

    2012-02-01

    Temporal variation in selection is a fundamental determinant of evolutionary outcomes. A recent paper presented a synthetic analysis of temporal variation in selection in natural populations. The authors concluded that there is substantial variation in the strength and direction of selection over time, but acknowledged that sampling error would result in estimates of selection that were more variable than the true values. We reanalyze their dataset using techniques that account for the necessary effect of sampling error to inflate apparent levels of variation and show that directional selection is remarkably constant over time, both in magnitude and direction. Thus we cannot claim that the available data support the existence of substantial temporal heterogeneity in selection. Nonetheless, we conject that temporal variation in selection could be important, but that there are good reasons why it may not appear in the available data. These new analyses highlight the importance of applying techniques that estimate parameters of the distribution of selection, rather than parameters of the distribution of estimated selection (which will reflect both sampling error and "real" variation in selection); indeed, despite availability of methods for the former, focus on the latter has been common in synthetic reviews of the aspects of selection in nature, and can lead to serious misinterpretations. © 2011 The Author(s). Evolution© 2011 The Society for the Study of Evolution.

  17. Some Remarks on the Effects of Productivity on Growth

    Directory of Open Access Journals (Sweden)

    Zsolt Gilányi

    2007-07-01

    Full Text Available Standard economic models predict that a ceteris paribus increase in the overall productivity results in an increased production if the economy departs from an equilibrium state. We show that this result is valid under specific conditions In other cases, even if the initial conditions of an economic system are so that the economy converges into (or starts from an equilibrium state, the increase of overall productivity generally results, in the long run, in the collapse of the economy due to the unbalanced change in the money holdings. Hence, in general, an appropriate expansive monetary policy should accompany the increase of productivity.

  18. 2011 Asia Pacific Few-Body Conference Summary Remarks

    International Nuclear Information System (INIS)

    Gibson, B. F.

    2013-01-01

    These remarks represent the author’s personal perspective regarding ideas presented at this fifth Asia Pacific Conference on Few-Body Problems in Physics. They are not intended as a comprehensive summary of what we witnessed during this week of stimulating presentations and intense discussions. However, these remarks do characterize some of the physics we heard and some of the key questions raised. The ideas presented will hopefully outlive the rapporteurs who brought their work and that of others to our attention here in the International Hall of the Sungkyunkwan University in Seoul, Republic of Korea. (author)

  19. A Remarkable Recent Transition in the Solar Dynamo

    NARCIS (Netherlands)

    de Jager, C.; Akasofu, S.-I.; Duhau, S.; Livingston, W.C.; Nieuwenhuijzen, H.; Potgieter, M.S.

    2016-01-01

    We summarize the major aspects of the remarkable, fairly long lasting period(∼ 2005 to ∼ 2010) of low solar activity, that we will call the Transition. It is the transitionalstage between the Grand Maximum of the 20th century and a forthcoming (most probablyRegular) episode of solar activity. The

  20. Remarks on the low value obtained for the Hubble constant

    International Nuclear Information System (INIS)

    Jaakkola, Toivo

    1975-01-01

    Some remarks are made on the basis of the data given by Sandage and Tamman, suggesting that these authors have over-estimated the distances to the most luminous galaxies and obtained a value too low for the Hubble constant [fr

  1. Collisionless shocks and upstream waves and particles: Introductory remarks

    International Nuclear Information System (INIS)

    Kennel, C.F.

    1981-01-01

    We discuss more aspects of collisionless shock theory that might be pertinent to the problem of upstream waves and particles. It is hoped that our qualititive remarks may be a useful guide for the general reader as he goes through the detailed papers to come

  2. Some remarks on electron scattering in a laser field

    International Nuclear Information System (INIS)

    Ehlotzky, F.

    1988-01-01

    Potential scattering of electrons in a quantized radiation field is reconsidered. Some remarks are made on the validity of the Kroll-Watson scattering formula and on the close connection of this formula with the classical transition rate of scattering in a radiation field. (17 refs.)

  3. Polypyridyl iron(II) complexes showing remarkable photocytotoxicity ...

    Indian Academy of Sciences (India)

    aditya

    Polypyridyl iron(II) complexes showing remarkable photocytotoxicity in visible light. ADITYA GARAI a. , UTTARA BASU a. , ILA PANT b. , PATURU KONDAIAH*. ,b. AND. AKHIL R. CHAKRAVARTY*. ,a a. Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore. 560012, India. E-mail: ...

  4. Discussant Remarks on Session: Statistical Aspects of Measuring the Internet

    Energy Technology Data Exchange (ETDEWEB)

    Cottrell, Les

    1999-04-02

    These remarks will briefly summarize what we learn from the talks in this session, and add some more areas in Internet Measurement that may provide challenges for statisticians. It will also point out some reasons why statisticians may be interested in working in this area.

  5. The European Public Prosecutor's Office (EPPO): Introductory Remarks

    NARCIS (Netherlands)

    Vervaele, J.A.E.

    2018-01-01

    These introductory remarks deal with the reasons why the EPPO is perceived by some as a controversial body. These reasons are mirrored with the problem identification and the causes thereof. The size of EU fraud and related corruption and money laundering, both at the income and expenditure side, is

  6. Remarks concerning two sympatric seedeaters Poliospiza spp. in ...

    African Journals Online (AJOL)

    Turner, D.A., Finch, B.F, & Hunter, N.D. Remarks concerning the all-black coastal boubous. (Laniarius ... Currently, however, there is little evidence to support such a theory, and it is .... twigs with its beak in order to increase the size of the hole.

  7. Some remarks on the Bonnor-Swaminarayan solution

    International Nuclear Information System (INIS)

    Berezdivin, R.; Herrera, L.

    1976-01-01

    The letter re-examines the Bonnor-Swaminarayan solution with the aim to try a clarification of its physical interpretation. The radiative nature of the solution as suggested by Bicak is questioned and some remarks on this topic are given

  8. Remarkable recoveries: research and practice from a patient's perspective.

    Science.gov (United States)

    Barasch, Marc Ian

    2008-08-01

    Mind-body therapies are often portrayed in the literature as self-palliative, adjunctive, and complementary, but rarely as contributive to cure. Many physicians continue to view them as acceptable indulgences so long as they are harmless and the patient remains fully compliant with a standard treatment regimen. The possibility that such modalities might help drive the healing process itself is infrequently acknowledged. This article addresses the topic of such therapies, examining remarkable recoveries in cancer, and suggesting the need for a "Remarkable Recovery Registry" to expand the literature on these cases. The author discusses the importance of complementary alternative medicine, and emotional and pyschologic support in the treatment regimen, and the need for health care providers and patients to work together to provide the best emotional environment for the healing process.

  9. Adiabatic analysis of collisions. III. Remarks on the spin model

    International Nuclear Information System (INIS)

    Fano, U.

    1979-01-01

    Analysis of a spin-rotation model illustrates how transitions between adiabatic channel states stem from the second, rather than from the first, rate of change of these states, provided that appropriate identification of channels and scaling of the independent variable are used. These remarks, like the earlier development of a post-adiabatic approach, aim at elucidating the surprising success of approximate separation of variables in the treatment of complex mechanical systems

  10. A remark on the energy conditions for Hawking's area theorem

    Science.gov (United States)

    Lesourd, Martin

    2018-06-01

    Hawking's area theorem is a fundamental result in black hole theory that is universally associated with the null energy condition. That this condition can be weakened is illustrated by the formulation of a strengthened version of the theorem based on an energy condition that allows for violations of the null energy condition. With the semi-classical context in mind, some brief remarks pertaining to the suitability of the area theorem and its energy condition are made.

  11. Remarks of the SFRP working group about ICRP recommendations

    International Nuclear Information System (INIS)

    Schieber, C.; Cordoliani, Y.S.

    2005-01-01

    Remarks of the SFRP working group about ICRP recommendations. The International Commission on Radiological Protection has proposed last summer on its Web site the draft text of the 2005 ICRP recommendations for consultation. As it was done for the previous drafts, the French Society for Radiation Protection, has sent his comments to the ICRP, through a specific working group. The text sent to the ICRP is presented here to the readers of the SFRP's Journal. (author)

  12. Remarks on search methods for stable, massive, elementary particles

    International Nuclear Information System (INIS)

    Perl, Martin L.

    2001-01-01

    This paper was presented at the 69th birthday celebration of Professor Eugene Commins, honoring his research achievements. These remarks are about the experimental techniques used in the search for new stable, massive particles, particles at least as massive as the electron. A variety of experimental methods such as accelerator experiments, cosmic ray studies, searches for halo particles in the galaxy and searches for exotic particles in bulk matter are described. A summary is presented of the measured limits on the existence of new stable, massive particle

  13. Remarks on the 'Grenelle Environnement' portfolio of measures

    International Nuclear Information System (INIS)

    2009-01-01

    The Boston Consulting Group has presented its remarks on the economic impact of the portfolio of measures issued from the 'Grenelle de l'Environnement' workshop that was held in France and involved people with a variety of backgrounds (government representatives, politicians, companies, professional syndicates, NGOs, scientists and university professors, etc.). These measures (covering sectors such as agriculture, biodiversity, wastes, renewable energies, transport, buildings, risk prevention, etc.) are said to potentially generate 450 billions Euros of economic activities and 600,000 jobs during 12 years. Their direct impacts on the environment would be a 14 percent reduction in greenhouse gases between 2010 and 2020. Concerning renewable energies, investment focusing is suggested

  14. Remarks on Hamiltonian structures in G2-geometry

    International Nuclear Information System (INIS)

    Cho, Hyunjoo; Salur, Sema; Todd, A. J.

    2013-01-01

    In this article, we treat G 2 -geometry as a special case of multisymplectic geometry and make a number of remarks regarding Hamiltonian multivector fields and Hamiltonian differential forms on manifolds with an integrable G 2 -structure; in particular, we discuss existence and make a number of identifications of the spaces of Hamiltonian structures associated to the two multisymplectic structures associated to an integrable G 2 -structure. Along the way, we prove some results in multisymplectic geometry that are generalizations of results from symplectic geometry

  15. Unbound color, prefaced by remarks on baryon spectroscopy

    International Nuclear Information System (INIS)

    Greenberg, O.W.

    Theoretical and experimental issues related to the possibility that color is unbound are surveyed. This implies that quarks, gluons and other particles carrying color can exist as isolated objects. It is surprisingly difficult to distinguish models with unbound color from those in which color is permanently confined. None-the-less, the present situation seems discouraging for unbound color because there is no unambiguous support for it and because the crucial prediction of formation of a colored gluon in e + e - collisions has been ruled out wherever sufficient data exists. The above survey is prefaced by remarks on the symmetric quark model for baryon spectroscopy

  16. Remarkable rates of lightning strike mortality in Malawi.

    Science.gov (United States)

    Mulder, Monique Borgerhoff; Msalu, Lameck; Caro, Tim; Salerno, Jonathan

    2012-01-01

    Livingstone's second mission site on the shore of Lake Malawi suffers very high rates of consequential lightning strikes. Comprehensive interviewing of victims and their relatives in seven Traditional Authorities in Nkhata Bay District, Malawi revealed that the annual rate of consequential strikes was 419/million, more than six times higher than that in other developing countries; the rate of deaths from lightning was 84/million/year, 5.4 times greater than the highest ever recorded. These remarkable figures reveal that lightning constitutes a significant stochastic source of mortality with potential life history consequences, but it should not deflect attention away from the more prominent causes of mortality in this rural area.

  17. Some Remarks on Stochastic Versions of the Ramsey Growth Model

    Czech Academy of Sciences Publication Activity Database

    Sladký, Karel

    2012-01-01

    Roč. 19, č. 29 (2012), s. 139-152 ISSN 1212-074X R&D Projects: GA ČR GAP402/10/1610; GA ČR GAP402/10/0956; GA ČR GAP402/11/0150 Institutional support: RVO:67985556 Keywords : Economic dynamics * Ramsey growth model with disturbance * stochastic dynamic programming * multistage stochastic programs Subject RIV: BB - Applied Statistics, Operational Research http://library.utia.cas.cz/separaty/2013/E/sladky-some remarks on stochastic versions of the ramsey growth model.pdf

  18. Remarkable Computing - the Challenge of Designing for the Home

    DEFF Research Database (Denmark)

    Petersen, Marianne Graves

    2004-01-01

    The vision of ubiquitous computing is floating into the domain of the household, despite arguments that lessons from design of workplace artefacts cannot be blindly transferred into the domain of the household. This paper discusses why the ideal of unremarkable or ubiquitous computing is too narrow...... with respect to the household. It points out how understanding technology use, is a matter of looking into the process of use and on how the specific context of the home, in several ways, call for technology to be remarkable rather than unremarkable....

  19. Remarkable convergent evolution in specialized parasitic Thecostraca (Crustacea)

    DEFF Research Database (Denmark)

    Pérez-Losada, Marcos; Høeg, Jens Thorvald; Crandall, Keith A

    2009-01-01

    the metamorphosis found in the Facetotecta and Rhizocephala suggests a common evolutionary origin, but until now no comprehensive study has looked at the basic evolution of these thecostracan groups. Results To this end, we collected DNA sequences from three nuclear genes [18S rRNA (2,305), 28S rRNA (2...... analyses indicate a convergent evolution of the very similar and highly reduced slug-shaped stages found during metamorphosis of both the Rhizocephala and the Facetotecta. This provides a remarkable case of convergent evolution and implies that the advanced endoparasitic mode of life known from...

  20. Concluding remarks: Faraday Discussion on chemistry in the urban atmosphere.

    Science.gov (United States)

    Jimenez, Jose L

    2016-07-18

    This article summarises the Concluding remarks from the Faraday Discussion on Chemistry in the Urban Atmosphere. The following themes are addressed: (a) new results that inform our understanding of the evolving sources and composition of the urban atmosphere ("News"); (b) results that identify gaps in our understanding that necessitate further work ("Gaps"); (c) the emerging instrumentation revolution and some of the challenges that it brings; (d) the structural issues of insufficient support for the analysis of field campaigns; and (e) some important areas that were missing from this Faraday Discussion and that should receive an increasing focus in the future.

  1. Escaping the flybottle: solipsism and method in Wittgenstein's Philosophical Remarks

    Directory of Open Access Journals (Sweden)

    Jônadas Techio

    2012-12-01

    Full Text Available The paper supports a dialectical interpretation of Wittgenstein's method focusing on the analysis of the conditions of experience presented in his Philosophical Remarks. By means of a close reading of some key passages dealing with solipsism I will try to lay bare their self-subverting character: the fact that they amount to miniature dialectical exercises offering specific directions to pass from particular pieces of disguised nonsense to corresponding pieces of patent nonsense. Yet, in order to follow those directions one needs to allow oneself to become simultaneously tempted by and suspicious of their all-too-evident "metaphysical tone" - a tone which, as we shall see, is particularly manifest in those claims purporting to state what can or cannot be the case, and, still more particularly, those purporting to state what can or cannot be done in language or thought, thus leading to the view that there are some (determinate things which are ineffable or unthinkable. I conclude by suggesting that in writing those remarks Wittgenstein was still moved by an ethical project, which gets conspicuously displayed in these reiterations of his attempts to cure the readers (and himself from some of the temptations expressed by solipsism.

  2. Remarks before the Beijing meeting of the pacific basin conference

    International Nuclear Information System (INIS)

    Rusche, B.C.

    1987-01-01

    A substantial amount of new generating capacity must be added in the United States before the turn of the century. Noting that the Light Water Reactor (LWR) has enjoyed a remarkably good safety record, the United States Department of Energy (DOE) is working actively to restore public and investor confidence in nuclear power. DOE is working with U.S. industry to encourage licensing reform, simplification and standardization of large plant designs, and resolution of the waste managment issues. We also are pursuing new, more tolerant, lower cost designs and are prepared to share our technology advances with other nations under mutually acceptable conditions and are determined to be a reliable supplier of equipment and enrichment services. (author)

  3. Allotropes of Phosphorus with Remarkable Stability and Intrinsic Piezoelectricity

    Science.gov (United States)

    Li, Zhenqing; He, Chaoyu; Ouyang, Tao; Zhang, Chunxiao; Tang, Chao; Römer, Rudolf A.; Zhong, Jianxin

    2018-04-01

    We construct a class of two-dimensional (2D) phosphorus allotropes by assembling a previously proposed ultrathin metastable phosphorus nanotube into planar structures in different stacking orientations. Based on first-principles methods, the structures, stabilities, and fundamental electronic properties of these allotropes are systematically investigated. Our results show that these 2D van der Waals phosphorene allotropes possess remarkable stabilities due to the strong intertube van der Waals interactions, which cause an energy release of about 30 - 70 meV /atom , depending on their stacking details. Most of them are confirmed to be energetically more favorable than the experimentally viable α -P and β -P . Three of them, showing a relatively higher probability of being synthesized in the future, are further confirmed to be dynamically stable semiconductors with strain-tunable band gaps and intrinsic piezoelectricity, which may have potential applications in nanosized sensors, piezotronics, and energy harvesting in portable electronic nanodevices.

  4. Some remarks on the design of HIF current multiplication rings

    International Nuclear Information System (INIS)

    Reich, K.H.

    1983-12-01

    The conceptual design of heavy ion fusion drivers has now reached a state, where the overall approach has become fairly clear. One design features an RF linac plus current and beam multiplication rings. The present remarks concern the assignment of multiturn injection, beam storage and bunching to an optimized number of rings and transport lines, as well as some criteria for their designs. The main parameter constraints are discussed, showing how they can be met, although there is little flexibility at the present stage of understanding and technology. A shortened version of this report is scheduled for presentation at the ''INS International Symposium on Heavy Ion Accelerators and Their Application to Inertial Fusion'' Tokyo, January 23-27 1984. (author)

  5. Remarks on the Colonized Libido: Trying to Think beyond Patriarchy

    Directory of Open Access Journals (Sweden)

    Hilan Bensusan

    2004-01-01

    Full Text Available In these remarks I attempt to think through some of the consequences of the way we conceive and live our desires. I try to contrast those desires with both our idea of freedom and the way we usually understand nature. This takes me quickly to issues such as pornography, male identity and then to how we gain and preserve our self-esteem. This, in turn, takes me to issues that are somehow linked to the institutional and emotional structures of patriarchy under a regime of heterosexuality as a norm. I try to consider these issues from the point of view of someone who was trained within the practices and thoughts of masculinity and is bothered by the consequences of such training. I endeavour to find a way to rethink the colonization of our desires so that we can find paths to an exercise of our capacities of desire that could be somehow freer.

  6. The Social Interplay of Disciplinarity and Interdisciplinarity. Some Introductory Remarks

    Directory of Open Access Journals (Sweden)

    Reinhold Hedtke

    2006-12-01

    Full Text Available Social Science Education as a subject field in schools is an intrinsic pluridisciplinary feature, whatever disciplines are included, however it may be organised and wherever it may be institutionalised. Civic education, economic education, social education and historical education each comprise several academic disciplines even if they are thought to be completely independent subjects. From the start on, disciplinarity and interdisciplinarity are on the agenda for any subject related to social science education and are one of its main problems. For these introductory remarks interdisciplinarity can be simply defined as relating two or more academic disciplines or school subjects to each other if this is done in a purposeful, systematic, explicit and reflective way. The overarching goal is to improve education that is to enhance students' understandings of the worlds and their abilities to act within and towards them. A relationship between disciplines or subjects which misses one or more of the four characteristics can be called pluridisciplinary or multidisciplinary (cf. Audigier 2006. In the following I first want to discuss some aspects of disciplinarity and interdisciplinarity at schools and at universities and the weakness of interdisciplinarity. I sketch some social science based ideas on the interrelationship between the subject structure of the academic world and the world of schools (3. and of some tendency to commonalities or even unification of social sciences and related competencies (4.. I conclude with some remarks on different kinds of knowledge (5.. Last but not least, I'll give an overview on the papers in this issue of the Journal of Social Science Education (6..

  7. Remarkable reduction of thermal conductivity in phosphorene phononic crystal

    International Nuclear Information System (INIS)

    Xu, Wen; Zhang, Gang

    2016-01-01

    Phosphorene has received much attention due to its interesting physical and chemical properties, and its potential applications such as thermoelectricity. In thermoelectric applications, low thermal conductivity is essential for achieving a high figure of merit. In this work, we propose to reduce the thermal conductivity of phosphorene by adopting the phononic crystal structure, phosphorene nanomesh. With equilibrium molecular dynamics simulations, we find that the thermal conductivity is remarkably reduced in the phononic crystal. Our analysis shows that the reduction is due to the depressed phonon group velocities induced by Brillouin zone folding, and the reduced phonon lifetimes in the phononic crystal. Interestingly, it is found that the anisotropy ratio of thermal conductivity could be tuned by the ‘non-square’ pores in the phononic crystal, as the phonon group velocities in the direction with larger projection of pores is more severely suppressed, leading to greater reduction of thermal conductivity in this direction. Our work provides deep insight into thermal transport in phononic crystals and proposes a new strategy to reduce the thermal conductivity of monolayer phosphorene. (paper)

  8. Teletandem between French and Brazilian students: Some preliminary remarks

    Directory of Open Access Journals (Sweden)

    Liliane SANTOS

    2015-12-01

    Full Text Available ABSTRACT In its French-Brazilian version, the Teletandem Brazil project enables students from the University of Lille 3 (France and from the State University of São Paulo (Unesp, Brazil, to take part in online exchanges, based on the principles of autonomy and reciprocity. In this work, we will present some preliminary remarks on the construction of cultural identity representations by the students who took part in the project, from 2006 to 2012, the specificity of the exchanges we analyze being that most of the French students involved in them are third generation Portuguese. We will examine the consequences of the introduction of a third culture within exchanges which, linguistically speaking, are bilateral. The French students are often experiencing conflicting feelings toward Brazil and, similarly, the Brazilian students may have conflicting feelings towards Portugal and France. Our preliminary results show that the most successful linguistic exchanges occur when students face their own cultural identity with no feeling of superiority or inferiority.

  9. Remark on state vector construction when flavor mixing exists

    International Nuclear Information System (INIS)

    Fujii, K.; Shimomura, T.

    2006-01-01

    In the framework of quantum field theory, we consider the way to construct the one-particle state (with definite 3-momentum) when particle mixing exists, such as in the case of flavor-neutrino mixing. In the preceding report (Prog. Theor. Phys. 112, 901 (2004)), we have examined the structure of expectation values of the flavor neutrino charges (at time t) with respect to a neutrino-source state prepared at time t' (earlier than t). When there is no mixing, each of various contributions to the expectation value is equal, in its dominant part, to the transition probability corresponding to the respective neutrino-production process. On the basis of the assumption that such an equality holds also in the mixing case, we can find an appropriate form of one-flavor-neutrino state with 3-momentum and helicity. Along the same way, we examine the boson case when flavor mixing exists. We give remarks on the relation and difference between the ordinary and the present approaches to flavor oscillation

  10. Remarkable Women in a Remarkable Age. On the Genesis of the English Public Sphere, 1642-1752

    Directory of Open Access Journals (Sweden)

    Eleonora Cappuccilli

    2015-06-01

    Full Text Available During the era of the English Revolutions and shortly after that, some spaces, albeit limited, of female visibility open up. Thanks to the window of opportunity caused by the collapse of censorship, the participation in the radical sects and in the Civil war, some remarkable women succeed in introducing themselves in the public sphere, shaping it since its very genesis. Moreover, analysing law institutions as jointure and feoffment, the attempt is to reconstruct some fragments of juridical female autonomy, which belie the total pervasiveness of coverture in the XVII century. As in private law, in public law women, in the role of queens, gain centrality: the principle of female authority, while safeguards the holding of the monarchical regime, destabilizes its patriarchal structure. Going through the works of Katherine Chidley, Margaret Cavendish, Damaris Masham and Mary Astell, the essay aims at reconstructing women's public voice, a voice which upsets the consolidated frames and subverts the established positions, questioning the same social hierarchies.

  11. Concluding remarks of international symposium on highly excited states in nuclear reactions

    Energy Technology Data Exchange (ETDEWEB)

    Bernstein, A. M.; Ikegami, H.; Muraoka, M. [eds.

    1980-01-01

    This is the concluding remarks in the international symposium on highly excited states in nuclear reactions. The remarks concentrate on the giant quadrupole states. In the framework of the distorted wave Born approximation (DWB), the differential cross section can be deduced. The relevant transition matrix elements are defined, and the quantities which are measured in inelastic hadron (h, h') reactions are shown. These are used to obtain both neutron and proton transition multipole matrix elements. This is equivalent to make the isospin decomposition of the electromagnetic transition matrix elements. The ratios of the transition matrix elements of neutrons and protons of the lowest 2/sup +/ states in even-even single closed shell nuclei are evaluated and compared with experimental results. For each nucleus, the consistency between various measurements is generally good. The effect of the virtual excitation of giant 2/sup +/ states into the ground and first excited states of even-even nuclei is discussed. The accuracy of (h, h') results can be tested.

  12. A case of parotid tumor showing remarkable regression following hyperthermo-chemo-radiotherapy

    International Nuclear Information System (INIS)

    Fujimura, Takashi; Yonemura, Yutaka; Kamata, Toru

    1987-01-01

    A 72-year-old woman developed adenocarcinoma of the left parotid gland. Because of the excessive size of her tumor and the fact that she suffered from severe liver dysfunction, she was treated by hyperthermo-chemo-radiotherapy (HCR therapy). After ten sessions of radiofrequency hyperthermia with HEH 500 (13.56 MHz radiofrequency wave), 50-Gy irradiation from a linac and administration of 33.0 g of tegafur in suppository form, the tumor mass showed remarkable regression decreasing in size by as much as 84 % on computed tomography. Histologically, the tumor which was resected under local anesthesia, showed almost total necrosis. The multidisciplinary HCR therapy was well tolerated and effective as a therapy for cancer in this case. (author)

  13. Remarkable separability of circulation response to Arctic sea ice loss and greenhouse gas forcing

    Science.gov (United States)

    McCusker, K. E.; Kushner, P. J.; Fyfe, J. C.; Sigmond, M.; Kharin, V. V.; Bitz, C. M.

    2017-08-01

    Arctic sea ice loss may influence midlatitude climate by changing large-scale circulation. The extent to which climate change can be understood as greenhouse gas-induced changes that are modulated by this loss depends on how additive the responses to the separate influences are. A novel sea ice nudging methodology in a fully coupled climate model reveals that the separate effects of doubled atmospheric carbon dioxide (CO2) concentrations and associated Arctic sea ice loss are remarkably additive and insensitive to the mean climate state. This separability is evident in several fields throughout most of the year, from hemispheric to synoptic scales. The extent to which the regional response to sea ice loss sometimes agrees with and sometimes cancels the response to CO2 is quantified. The separability of the responses might provide a means to better interpret the diverse array of modeling and observational studies of Arctic change and influence.

  14. Some remarks on the significance of low doses

    International Nuclear Information System (INIS)

    Cigna, A.A.

    1989-12-01

    The criteria of the present system of individual dose limitation are considered as well as the evolution of the limiting values. The assumption of the linearity of the dose-effect relationship without any threshold is probably the best approach to adopt for recommendations in radiation protection and for accounting the doses acquired by exposure to ionizing radiation. On the other hand the present evaluation of the natural background could imply a different dose-effect relationship in the low doses region and perhaps the existence of a threshold. Therefore the extrapolations which are usually made after exposures of different groups of people to low doses cannot be considered as scientifically sound. (author)

  15. Remarks on doubly special relativity theories and gravity

    International Nuclear Information System (INIS)

    Hinterleitner, F

    2008-01-01

    Modifications of special relativity by the introduction of an invariant energy and/or momentum level (so-called doubly special relativity theories, DSR) or by an energy-momentum dependence of the Planck constant (generalized uncertainty principle, GUP) are compared with classical gravitational effects in an interaction process. For the low-energy limit of the usual formulations of DSR to be equivalent to Newtonian gravity, a restrictive condition is found. GUP yields an effective repulsion, in analogy to gravitational repulsion in loop quantum cosmology

  16. The remarkable Red Rectangle: A Stairway to Heaven?

    Science.gov (United States)

    2004-05-01

    responsible for the striking red colour of the Rectangle is not yet clear, but it is likely that they are some kind of hydrocarbon formed in the cool outflows from the central star. Another remarkable feature of the Red Rectangle, visible only with the superb resolution of the Hubble telescope, is the dark band passing across the central star. This is the shadow of a dense disc of dust that surrounds the star and obscures it from direct view. The light we see streams out along the axis of the disc, and is scattered towards us by dust particles. Astronomers have found that the central star is actually a close pair of stars orbiting each other with a period of about 10.5 months. Interactions between these stars have probably caused the ejection of the thick dust disc that obscures our view of the binary. The disc then funnels subsequent dust and gas outflows out along its axis, forming the bizarre bi-conical structure we see as the rung of the Red Rectangle. The reasons for these fresh periodic ejections of more gas and dust remain unknown. The Red Rectangle was first discovered during a rocket flight in the early 1970s, in which astronomers were searching for strong sources of infrared radiation. This infrared source lies about 2300 light-years from Earth in the direction of the constellation Monoceros. Stars surrounded by clouds of dust are often strong infrared sources because the dust is heated by the starlight and then re-radiates long-wavelength red light. Studies of HD 44179 with ground-based telescopes revealed a rectangular shape in the dust surrounding the star at the centre, leading to the name 'Red Rectangle', coined in 1973 by astronomers Martin Cohen and Mike Merrill. This image was made from observations taken on 17-18 March 1999 with Hubble’s Wide Field Planetary Camera 2.

  17. Some remarks on chiral symmetry in dense matter

    International Nuclear Information System (INIS)

    Kaellman, C.G.; Montonen, C.

    1982-01-01

    The restoration of chiral symmetry in quantum chromodynamics as the temperature T and the chemical potential vertical stroke μ vertical stroke are increased is discussed qualitatively and using effective field theories. The latter are shown not to give reliable quantitative estimates. It is argued that a dilute gas of instantons cannot be the main dynamical agent responsible for the breakdown of chiral symmetry. (orig.)

  18. Introductory remarks: the importance of the initial response

    International Nuclear Information System (INIS)

    Lincoln, T.A.

    1980-01-01

    The role of preparedness for a radiation accident and the diagnostic and therapeutic management of patients who have been overexposed will be the basis of this report. Special attention will be given to the effects of delay of initiating appropriate core and the state of ignorance about the management of radiation injuries of most practitioners

  19. Some Remarks on Exp-Function Method and Its Applications

    International Nuclear Information System (INIS)

    Aslan Ismail; Marinakis Vangelis

    2011-01-01

    Recently, many important nonlinear partial differential equations arising in the applied physical and mathematical sciences have been tackled by a popular approach, the so-called Exp-function method. In this paper, we present some shortcomings of this method by analyzing the results of recently published papers. We also discuss the possible improvement of the effectiveness of the method. (general)

  20. Some remarkable spin physics with monopoles and fermions

    International Nuclear Information System (INIS)

    Craigie, N.S.

    1984-01-01

    This review will cover the following topics, which follow the historical evolution of the subject: the Dirac monopole; the Kazama-Yang Goldhaber problem in electron-monopole scattering; the 't Hooft-Polyakov monopole and spin from isospin; the Rubakov analysis; monopole catalysis of proton decay the Rubakov-Callan effect; the role of exactly solvable 2-dimensional QFT's and finally observable consequences. 15 references

  1. Some remarkable spin physics with monopoles and fermions

    International Nuclear Information System (INIS)

    Craigie, N.S.

    1984-09-01

    This review will cover the following topics, which follow the historical evolution of the subject: the Dirac monopole, the Kazama-Yang Goldhaber problem in electron-monopole scattering; the 't Hooft-Polyakov monopole and spin from isospin; the Rubakov analysis; monopole catalysis of proton decay- ''the Rubakov-Callan effect''; the role of exactly solvable 2-dimensional QFT's and finally observable consequences. (author)

  2. Remarks on the mathematical description of materials damage by irradiation

    International Nuclear Information System (INIS)

    Steinbach, E.

    1987-01-01

    In describing radiation damage processes in materials, the chemical rate theory proves to be the most effective mathematical method. The applicability, and even the validity, of this theory, which has been successfully applied in many other scientific fields, have been questioned by some authors. After rigorous mathematical analysis of the relevant rate equations and the corresponding self-consistent calculation of sink strengths, the main criticisms on this subject can be disproved

  3. Remarks on Remnants by Fermions’ Tunnelling from Black Strings

    Directory of Open Access Journals (Sweden)

    Deyou Chen

    2014-01-01

    Full Text Available Hawking’s calculation is unable to predict the final stage of the black hole evaporation. When effects of quantum gravity are taken into account, there is a minimal observable length. In this paper, we investigate fermions’ tunnelling from the charged and rotating black strings. With the influence of the generalized uncertainty principle, the Hawking temperatures are not only determined by the rings, but also affected by the quantum numbers of the emitted fermions. Quantum gravity corrections slow down the increases of the temperatures, which naturally leads to remnants left in the evaporation.

  4. Remarks on Fermion-Boson equivalence in three dimensions

    International Nuclear Information System (INIS)

    Dutra, A. de Souza; Natividade, C.P.

    1998-06-01

    Starting from a decomposition of the self-dual field in (2+1) dimensions, we build up an alternative quantum theory which consists of a self-dual model coupled to a Maxwell-generalized Chern-Simons theory. We discuss the fermion-boson equivalence of this quantum theory by comparing it to the Thirring model. Using these results we were able to compute the mass of the bosonized fermions up to third order in (1/m). Some problems related to the number of poles of the effective propagator are also addressed. (author)

  5. Remarks on Fermion-Boson equivalence in three dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Dutra, A de Souza [UNESP, Guaratingueta, SP (Brazil); Natividade, C P [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Inst. de Fisica

    1998-06-01

    Starting from a decomposition of the self-dual field in (2+1) dimensions, we build up an alternative quantum theory which consists of a self-dual model coupled to a Maxwell-generalized Chern-Simons theory. We discuss the fermion-boson equivalence of this quantum theory by comparing it to the Thirring model. Using these results we were able to compute the mass of the bosonized fermions up to third order in (1/m). Some problems related to the number of poles of the effective propagator are also addressed. (author) 13 refs.

  6. Review paper Personality and genes: remarks from a biological perspective

    Directory of Open Access Journals (Sweden)

    Grzegorz Węgrzyn

    2014-10-01

    Full Text Available Although there is no doubt that genes’ functions influence human personality, years of studies provided no clear picture on regulation of particular traits by specific genes. In this article, an overview of the complexity of the system of genetic control of personality is presented, and the level of complications of biological processes operating in this system is underlined. The methodology of studies devoted to determine effects of genes on personality traits is discussed, and limitations of various methods in such studies are indicated. Finally, suggestions for further research are listed and commented on. It is likely that to increase the level of our understanding of genetic mechanisms that modulate human personality, researchers conducting further studies will have to focus on using large sample sizes, performing independent replications, considering experiments on animal models, integrating cross-cultural data and epigenetic measures, and performing interdisciplinary experiments which combine methods of various disciplines, such as biology and psychology.

  7. A remark on fractional differential equation involving I-function

    Science.gov (United States)

    Mishra, Jyoti

    2018-02-01

    The present paper deals with the solution of the fractional differential equation using the Laplace transform operator and its corresponding properties in the fractional calculus; we derive an exact solution of a complex fractional differential equation involving a special function known as I-function. The analysis of the some fractional integral with two parameters is presented using the suggested Theorem 1. In addition, some very useful corollaries are established and their proofs presented in detail. Some obtained exact solutions are depicted to see the effect of each fractional order. Owing to the wider applicability of the I-function, we can conclude that, the obtained results in our work generalize numerous well-known results obtained by specializing the parameters.

  8. A remark concerning 20 plet dominance in charm decays

    CERN Document Server

    Bigi, Ikaros I

    1980-01-01

    Based on V spin consideration, it is argued that 20 plet dominance in the effective weak Lagrangian does not strongly reduce the inclusive decay rate of D/sup +/ mesons. Decays of the type D to K rho , K* pi , rho pi are discussed in pointing out that 20 dominance should lead to a large enhancement of D/sup +/ to K/sup 0/ rho /sup +/, (K/sup 0/)* pi /sup +/ over D/sup +/ to K/sup 0/ pi /sup +/; W exchange, on the other hand, leads to a sizeable suppression of D/sup 0/ to K/sup -/ rho /sup +/, (K/sup -/)* pi /sup +/ relative to D/sup 0/ to K/sup -/ pi /sup +/. (4 refs).

  9. Remarks to the local power oscillation phenomenon at BWRs

    International Nuclear Information System (INIS)

    Lange, Carsten; Hennig, Dieter; Hurtado, Antonio

    2011-01-01

    In the framework of BWR stability analysis, local neutron-flux oscillation events have attracted the attention of a number of researchers. In 1996, an unusual instability event occurred at Forsmark-1 in which superimposed on the classical, spatial mode oscillations, there were relatively large-amplitude, highly localised oscillations. Subsequent time-series analysis of the local power range monitor (LPRM) signals resulted in a space-dependent decay ratio, an inexplicable result. Furthermore, noise analysis-based localization techniques pointed towards the existence of two strong 'perturbation sources' in the two halves of the core, one of them coinciding with the radial position of an unseated bundle. In the scope of a theoretical work, the possibility of a space-dependent decay ratio was discussed but not comprehensively understood. Motivated by these findings the effect of local neutron-flux oscillations on the BWR stability behaviour is discussed and one possible interpretation is proposed which is able to explain the space dependent decay ratio and the long term oscillation pattern as well. The effect of the local neutron flux oscillating sources on the space and time dependent neutron field is described by a rigorous application of the mode expansion approach. The consequences to signal analysis are then discussed. It will be pointed out in the paper that when a BWR system is stable regarding power oscillations but driven by local neutron-flux oscillating sources, the decay ratio is on the one hand not space-dependent and on the other hand it does not indicate the real BWR stability behaviour. The RAM-ROM method is applied to the Forsmark case M2 and an operational point (KKB-B8) of NPP Brunsbüttel, where a local neutron-flux oscillation is superimposed on an unstable global power oscillation. The results of the bifurcation analysis, using BIFDD, and of the numerical integration are presented for KKB-B8 and Forsmark M2. (author)

  10. Carbonate porosity: some remarks; Porosidade em reservatorios carbonaticos: algumas consideracoes

    Energy Technology Data Exchange (ETDEWEB)

    Spadini, Adali Ricardo [PETROBRAS, Rio de Janeiro, RJ (Brazil). Exploracao e Producao]. E-mail: spadini@petrobras.com.br; Marcal, Rosely de Araujo [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2005-05-01

    Carbonate rocks are the major reservoirs of the largest super-giants fields in the world, including the Ghawar Field in Saudi Arabia, where the producing oil reservoir is the late Jurassic Arab-D limestone with five million barrels per day. Despite the great susceptibility to early diagenesis, that can dramatically modify the porous media, porosity values of carbonates remain essentially the same as that of deposition before burial. Porosity loss is essentially a subsurface process with a drastic reduction below 2500 m of burial depth. The occurrence of good reservoirs deeply buried, sometimes below 4,000 m, indicate that porosity can be preserved in subsurface in response to a series of mechanisms such as early oil emplacement, framework rigidity, abnormal pore pressure, among others. Percolation of geothermal fluids is a process considered to be responsible for generation of porosity in subsurface resulting in some good reservoir rocks. In Campos Basin, areas with burial around 2000 m, petrophysical data show a cyclic distribution that coincides with the shoaling upward cycles typical of the Albian carbonates. The greatest permeabilities coincide with the grain stones of the top of the cycles while the peloidal/oncolite wackestones/pack stones at the base show low values, reflecting the depositional texture. These relationships indicate that preservation of depositional porosity was very effective. The preservation of high porosity values for all the facies are related to early oil entrance in the reservoirs. In some cases, the presence of porosities of almost 30% in fine-grained peloidal carbonates, 3000 m of burial, without any clear effective preservation mechanism, suggest that corrosive subsurface brines have played an important role in porosity evolution. In Santos Basin, where reservoirs are deeply buried, only the grain stones have preserved porosity. The associated low energy facies has virtually no porosity. In this case, the depositional texture

  11. Some remarks on recent developments in micropolar continuum theory

    Science.gov (United States)

    Vilchevskaya, E. N.; Müller, W. H.

    2018-04-01

    This paper considers micropolar media that can undergo structural changes and do not a priori consist of indestructible material particles. Initially the pertinent literature is reviewed. Then the necessary theoretical framework for a continuum of that type is presented. The standard macroscopic equations for mass, linear and angular momentum are complemented by a recently proposed balance for the moment of inertia tensor, which contains a production term. Two examples illustrate the effect of the production. In the first example, we study a continuous stream of matter on a conveyor belt going through a crusher so that the total number of particles will change. In context with this example, it is also clear that the traditional Lagrangian way of describing the motion of solids is no longer adequate and must be replaced by the Eulerian point of view known from fluid mechanics. The second example deals with hollow particles which rotate because of the presence of body couples. Now a transient temperature field is superimposed such that the moment of inertia field changes due to the thermal expansion of particles. This in turn results in rotational motion that is no longer constant but varies in space and time.

  12. The role of research in nuclear regulation: Opening remarks

    International Nuclear Information System (INIS)

    Taylor, J.M.

    1997-01-01

    More than 20 years ago, the Energy Reorganization Act of 1974 created the USNRC and that same act provided for an office of nuclear regulatory research. It's what is called a statutory office within the NRC. In providing for an NRC research program, our Congress had several things to say about the character of the research that would be performed. First, NRC should perform such research as is necessary for the effective performance of the Commission's licensing and related regulatory functions. Second, the research may be characterized as confirmatory reassessment related to the safe operation and the protection of commercial reactors and other nuclear materials. Third, the NRC should have an independent capability for developing and analyzing technical information related to reactor safety, safeguards, and environmental protection in support of both the licensing and regulatory processes. Fourth, the research should not go beyond the need for confirmatory assessment, because the NRC should never be place in a position of having generated and then having to defend basic design data of its own. This has been and continues to be the role of research at the NRC. Somewhat different purposes might apply for regulatory agencies in other countries. Several regulatory agencies are represented here on this panel, so some of these difference may be discussed

  13. Biomimetics and the case of the remarkable ragworms

    Science.gov (United States)

    Hesselberg, Thomas

    2007-08-01

    Biomimetics is a rapidly growing field both as an academic and as an applied discipline. This paper gives a short introduction to the current status of the discipline before it describes three approaches to biomimetics: the mechanism-driven, which is based on the study of a specific mechanism; the focused organism-driven, which is based on the study of one function in a model organism; and the integrative organism-driven approach, where multiple functions of a model organism provide inspiration. The first two are established approaches and include many modern studies and the famous biomimetic discoveries of Velcro and the Lotus-Effect, whereas the last approach is not yet well recognized. The advantages of the integrative organism-driven approach are discussed using the ragworms as a case study. A morphological and locomotory study of these marine polychaetes reveals their biomimetic potential, which includes using their ability to move in slippery substrates as inspiration for novel endoscopes, using their compound setae as models for passive friction structures and using their three gaits, slow crawling, fast crawling, and swimming as well as their rapid burrowing technique to provide inspiration for the design of displacement pumps and multifunctional robots.

  14. The Remarkable Metrological History of Radiocarbon Dating [II].

    Science.gov (United States)

    Currie, Lloyd A

    2004-01-01

    This article traces the metrological history of radiocarbon, from the initial breakthrough devised by Libby, to minor (evolutionary) and major (revolutionary) advances that have brought (14)C measurement from a crude, bulk [8 g carbon] dating tool, to a refined probe for dating tiny amounts of precious artifacts, and for "molecular dating" at the 10 µg to 100 µg level. The metrological advances led to opportunities and surprises, such as the non-monotonic dendrochronological calibration curve and the "bomb effect," that gave rise to new multidisciplinary areas of application, ranging from archaeology and anthropology to cosmic ray physics to oceanography to apportionment of anthropogenic pollutants to the reconstruction of environmental history. Beyond the specific topic of natural (14)C, it is hoped that this account may serve as a metaphor for young scientists, illustrating that just when a scientific discipline may appear to be approaching maturity, unanticipated metrological advances in their own chosen fields, and unanticipated anthropogenic or natural chemical events in the environment, can spawn new areas of research having exciting theoretical and practical implications.

  15. LEDA 074886: A REMARKABLE RECTANGULAR-LOOKING GALAXY

    International Nuclear Information System (INIS)

    Graham, Alister W.; Spitler, Lee R.; Forbes, Duncan A.; Lisker, Thorsten; Janz, Joachim; Moore, Ben

    2012-01-01

    We report the discovery of an interesting and rare rectangular-shaped galaxy. At a distance of 21 Mpc, the dwarf galaxy LEDA 074886 has an absolute R-band magnitude of –17.3 mag. Adding to this galaxy's intrigue is the presence of an embedded, edge-on stellar disk (of extent 2 R e,disk = 12'' = 1.2 kpc) for which Forbes et al. reported v rot /σ ≈ 1.4. We speculate that this galaxy may be the remnant of two (nearly edge-on) merged disk galaxies in which the initial gas was driven inward and subsequently formed the inner disk, while the stars at larger radii effectively experienced a dissipationless merger event resulting in this 'emerald cut galaxy' having very boxy isophotes with a 4 /a = –0.05 to –0.08 from 3 to 5 kpc. This galaxy suggests that knowledge from simulations of both 'wet' and 'dry' galaxy mergers may need to be combined to properly understand the various paths that galaxy evolution can take, with a particular relevance to blue elliptical galaxies.

  16. Some remarks on the natural radiation burden of population

    International Nuclear Information System (INIS)

    Feher, I.; Gemesi, J.; Toth, A.

    1975-04-01

    A large scale of the population's radiation burden is due to the natural radioactivity of building materials. An appropriate model has been developed for the calculation of the burden of population from the concentration of radioisotopes in building materials. The external and internal radiation burden of Hungary's population were determined (weighted means were 33 mrem/year and the bronhial dose 730 mrad/year, respectively) and the effect of new building technologies and materials on the radiation burden was studied. In dwellings built of precast concrete slabs containing low-activity ballast available in Hungary the radiation burden was found to be significantly lower than the present average. The increase in the contamination hazard expected from the peaceful uses of atomic energy could be compensated by reducing the average external radiation burden together with the average bronchial dose. This reduction can be 1.6 mrem/year and 58 mrad/year, respectively (according to our estimations based on simple assumptions), requiring acceptable excess cost. (K.A.)

  17. Concluding remarks

    International Nuclear Information System (INIS)

    Okano, Kunihiko; Kikuchi, Mitsuru

    2005-01-01

    It is own goal to realize commercial tokamak fusion plants by the middle of this century. In this special issue, the problems that should be solved for the goal, the ITER's role as the way of solution and the development programs that could not be verified in ITER are described. Acquisition of marketability for practical use of fusion plants is not easy. However, it is expected that compactification of plants, realization of high-performance and low cost are proceeded by some new ideas. So we think that there is a good feasibility for the acquisition. In about 2100, the primary energy of maximum 20% will be supplied if the economic rationality is satisfied enough, and thus there is big significance in aiming at this. In addition, the characteristics such as inexpensiveness and stability in long-term use, security, environmental safety are also important elements. In the future, we will have to obtain fruitful results through participation to ITER, and it is essential to carry steadily out the projects to activate domestic research and development. For helping to understand this special issue, the summary of fusion development by tokamaks is attached as an appendix. (T.O.)

  18. Closing Remarks.

    Science.gov (United States)

    Reed

    1996-01-01

    About twenty years ago, the leaders of the National Cancer Institute (NCI) decided to start a new branch in the Clinical Oncology Program of the Division of Cancer Treatment. That new entity was named the Clinical Pharmacology Branch (CPB), and its first leader was a brilliant, young, promising investigator named Bruce A. Chabner. Chabner was educated at Yale and Harvard, and appeared to have an extraordinary grasp of novel concepts that were being developed in the emerging area of cancer chemotherapy. What the NCI leaders did not fully appreciate at the time was that they had just given birth to one of the most extraordinary careers in academic medicine. From the early seventies through the early eighties, Bruce Chabner developed a strong laboratory program that was based on scientific discovery and on the development of new talent. The CPB focused on new drug development, elucidation of drug mechanism(s) of action, and the development of new ways to use drugs that were already available. Concurrent with this laboratory effort was active participation in the development of clinical treatment regimens for Hodgkin's disease, non-Hodgkin's lymphoma, and other malignancies. Individuals who trained under Chabner are now cancer center directors, department heads, laboratory chiefs, and hold many other high-profile positions. From 1981 to 1995 Bruce Chabner was Director of the Division of Cancer Treatment (DCT) of the NCI. In that capacity he was Scientific Director of the Intramural Program within DCT, and he had oversight responsibility for the direction of extramural studies that were funded through the NCI, which were focused on the development of new treatments for human malignant disease. The NCI has five divisions for which the NCI Director has ultimate responsibility. While working with one NCI Director from 1981 to 1988, and with another from 1988 to 1995, and during the transition year of 1988, Bruce Chabner provided stability for the DCT while many changes were occurring throughout the five divisions of the NCI. How does one assess the impact of a career on a discipline such as cancer treatment? It's not easy! Each of the articles contributed to this tribute were written by a person who trained directly with Bruce Chabner, or was otherwise directly impacted by Bruce's guidance. As can be seen from the list of contributors to these Proceedings, each individual has made major contributions to the area of cancer treatment in his or her own right. However, Bruce's contribution to cancer treatment goes far beyond the individuals he trained. The many thousands of human lives who have benefited from his efforts cannot be accurately estimated, because his contributions have been so wide-ranging, as indicated below. Being "Scientific Director" is similar in a number of ways to being a football quarterback. One of those ways is that when things go well the quarterback may get a little too much credit, and when things go not-so-well the quarterback may get too much blame. However, it is the quarterback who "calls the plays." With that in mind, a partial list of the accomplishments of the Intramural Program of the DCT while Bruce Chabner was "quarterback" includes the following: * The first human retroviruses, HTLV-1 and HTLV-2, were discovered and shown to be directly linked to the development of specific human malignancies. * Adoptive immunotherapy for human cancer was developed, offering exciting new additions to the anticancer armamentarium. * Paclitaxel (Taxol®) was developed, and shown to be the most important new anticancer agent in the past two decades. * The human genes responsible for the development of several specific malignancies were discovered, such as those for kidney cancer. * Development of blood tests to detect HIV-tainted blood. * Treatment strategies for pediatric AIDS were developed. * The AIDS Drug Development Program within the NIH was established. * New drugs for the treatment of AIDS and AIDS-related conditions were developed. * The only three drugs to date that have been specifically approved for the treatment of AIDS-AZT, DDI, and DDC-were developed under the guidance of the DCT, with Bruce Chabner as Scientific Director. * The first clinical trials conducted with each of these agents-AZT, DDI, and DDC-were performed in the Intramural Program of the DCT. * Concurrently, many of the exciting findings reported by the National Surgical Adjuvant Breast and Bowel Project over the past 10 years (as well as other cooperative groups) were a direct result of the strong support shown by Bruce Chabner during his tenure as Director of the Division of Cancer Treatment. Further, the list above does not include his personal labortory and clinical accomplishments, some of which are: * Development of the principles of use of important antimetabolites, such as methotrexate. * Elucidation of biochemical pathways affected, and the mechanisms of action, of antifols and other antimetabolites. * The conduct of seminal studies in the clinical staging of non-Hodgkin's lymphomas, using laparoscopy as a primary tool. * Important contributions to the development of multiagent regimens in the clinical treatment of lymphomas, and of Hodgkin's disease. * Developed and is editor of the textbook which is considered to be the primary reference source for anticancer chemotherapeutic agents [1]. With all of these accomplishments, his career is long from over. Having just become the Medical Director of the Cancer Center at the Massachusetts General Hospital, Bruce Chabner is uniquely poised to have an even more far-reaching impact on a discipline in which he has played such a strong seminal role. This author was never a postdoctoral fellow in Bruce Chabner's laboratory. However, more than any other single person, he has played a central role in my professional development. I know of many others for whom the same statement would be true. It is a pleasure for me to witness the launching of the second phase of an already tremendous career. From Advances in Cancer Treatment: The Chabner Symposium. Stem Cells 1996;14:64-65.

  19. Introductory Remarks

    Science.gov (United States)

    Lu, Yi; Li, Yingfu

    The emergence of a large number of natural and artificial functional nucleic acids (FNAs; aptamers and nucleic acid enzymes, collectively termed functional nucleic acids in this book) has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and applications. In this volume, we have assembled some leading experts to provide a timely account of recent progress in sensing and other analytical applications that explore functional nucleic acids.

  20. Concluding remarks

    International Nuclear Information System (INIS)

    Rosen, L.

    1989-01-01

    There appeared to be unanimity on the proposition that energy and environmental problems are following a course which threatens to overwhelm all nations and all peoples unless we take corrective actions and soon. There also was unanimity on the thesis that many of the global problems require international cooperation and collaboration on a scale never before experienced and that this is a matter of survival. Nuclear energy, in its most horrible form, not only brought an end to a terrible war but has also served to discourage war between the major powers for more than 40 years, the longest such period in all of modern history, which dates back about 350 years. Nuclear arsenals, obnoxious though they are, have helped buy time for the world to put its political establishment on a path which makes global war less and less probable. This must continue but, in addition, we now need to buy time (50-100 years) to develop environmentally benign energy sources that are affordable and that will alleviate the instabilities imposed by islands of affluence in a sea of despair. This conference reinforces belief that nuclear energy can help mightily to solve that problem. In fact, it appears to be one of very few realistic options available to us. But we will fail in making this option available if we do find a way to increase the literacy of the world's people, and especially their leaders, about environmental matters generally and about the nuclear-energy option in particular. We must find ways to provide factual information with impeccable honesty and high credibility. I am hopeful that the information generated by this conference, widely disseminated, will help to do that and also to foster such conferences in the future

  1. Introductory remarks

    International Nuclear Information System (INIS)

    Soyeur, Madeleine.

    1980-10-01

    This paper introduces the discussion of the new aspects of nuclear studies with electrons and photons. It is mainly concerned with the short range part of the nuclear force and with the quark and gluon degrees of freedom that we believe are associated with it. The present description of the nucleon-nucleon force in non relativistic quark models and in bag models is reviewed. The assumption of a '6 quark' component in the deuteron and the possible existence of dibaryons are discussed

  2. Introductory remarks

    International Nuclear Information System (INIS)

    Panofsky, W.K.H.

    1994-01-01

    This paper is an introduction to the Tau Charm Factory workshop. To establish a firm scientific basis for future Tau Charm Factory plans one has to address the following two questions: (1) To what extent can and will work at other machines cover work that a Tau Charm Factory could do? Conversely (2) What are the required minimum parameters of a Tau Charm Factory which can do unique physics five years hence and beyond? This workshop has been organized to generate some preliminary answers in response to these two questions. Thus this Workshop is neither simply a scientific Workshop on the one hand or a planning session for specific machines on the other; rather it is something in between. During the workshop, specific plans or proposals for a Tau Charm Factory will be presented, but no attempt will be made to arrive at a consensus in response to such plans

  3. Concluding remarks

    International Nuclear Information System (INIS)

    Collier, J.G.

    1990-01-01

    The papers, all indexed separately, have been taking stock of the overall position as regards the development of fast reactors in Europe, the USSR, the USA and Japan. Good technical progress has been made with the development of this major source of electrical power for the next century. In Europe, there are two large prototypes operating, Phenix and PFR. There is also a 1200 MW e demonstration reactor (Superphenix), which is now continuing with its commissioning programme after the interruption caused by the leak from the fuel storage vessel. The Soviet Union is pressing ahead with its programme; in the USA FFTF has given outstanding reliability and in Japan the construction of Monju is going well and is on schedule for criticality in 1992. There has been general agreement on the basic economic and performance parameters of the fast reactor and its fuel cycle. In particular, after the first of a kind costs have been met, fast reactor and PWR generating costs are likely to be broadly similar, in the absence of large increases in uranium prices. However, the future of fast reactors is uncertain and the reasons for this are discussed. (author)

  4. Concluding remarks

    International Nuclear Information System (INIS)

    McCrea, W.H.

    1981-01-01

    A predominant aim of planetary exploration is to discover as much as possible about the origin of the Solar System. The conference papers and discussion are considered with this in mind. Comparative studies of surface features show that the 'geologies' of the terrestrial planets and the Moon and other large satellites are quite different. This is due in part to the presence or absence of water in various states. Other differences mentioned are the manifestations of tectonism and the chemical composition of these bodies. One paper suggests that interstellar molecules must have entered directly into the formation of the earth. Models for the major planets are proposed and satellites considered. The trend is to show that the formation of a satellite system must be a different process from the formation of a planetary system. Finally the formation of planets in pairs is noted. (U.K.)

  5. Closing remarks

    Indian Academy of Sciences (India)

    2007-12-12

    Dec 12, 2007 ... dian industry who had been involved in making magnet positioning systems and magnets for the LHC, as well as some ... the three regions went their separate ways. In fact, a large number of .... we are making decisions keeping in mind the cost of physics, we may also want to keep in mind the cost of these ...

  6. Concluding Remarks

    Energy Technology Data Exchange (ETDEWEB)

    Budker, G. I. [Institute of Nuclear Physics, Siberian Department of the USSR Academy Of Sciences, Novosibirsk, Union Of Soviet Socialist Republics (Russian Federation)

    1969-01-15

    I feel that the changes which have taken place in science in the last few years open up new possibilities, about which I should like to say a few words. In 1951 we began work on thermonuclear reactions in the confident belief that we would solve the problem with a rush and immediately. I was assigned the task of ensuring that our future thermonuclear reactor would not get too much out of hand. It was like the story of the man who wished to invent a perpetual motion machine and had taken out a patent on a method for keeping it under control. This attitude stemmed from the successes in developing ''explosive thermonuclear reactors'', a task which was achieved within a very short period of time, leaving physicists with the impression that they could do everything - and do it fast. However, experience soon showed that here we had a scientific rather than a technological problem and that it would be necessary to study in detail the physics of plasmas - which we have now been doing for over ten years.

  7. Closing Remarks

    International Nuclear Information System (INIS)

    Baird, S.

    2001-01-01

    Firstly I would like to start by thanking you all, the speakers for their excellent thought-provoking talks, the session chairmen for organizing and animating their sessions and keeping things both under control and reasonably on time. However, most importantly, I would to thank you all, the participants. Without your input, ideas and discussion, this workshop would not have been the success it has. (author)

  8. Closing Remarks

    Energy Technology Data Exchange (ETDEWEB)

    Baird, S

    2001-07-01

    Firstly I would like to start by thanking you all, the speakers for their excellent thought-provoking talks, the session chairmen for organizing and animating their sessions and keeping things both under control and reasonably on time. However, most importantly, I would to thank you all, the participants. Without your input, ideas and discussion, this workshop would not have been the success it has. (author)

  9. Introductory Remarks

    Czech Academy of Sciences Publication Activity Database

    Jandová, Anna; Jelínek, František; Pokorný, Jiří; Šrobár, Fedor

    2009-01-01

    Roč. 19, č. 4 (2009), s. 333-335 ISSN 1210-0552 Institutional research plan: CEZ:AV0Z20670512 Keywords : Biophysics * Cancer * Electromagnetic fields Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 0.475, year: 2009

  10. Introductory remarks

    NARCIS (Netherlands)

    Kiefer, Friedemann; Schulte-Merker, Stefan

    2014-01-01

    This introductory section briefly highlights the subsequent chapters in the context of recent findings and open questions in lymphatic vessel biology. It aims to provide a quick overview and orientation in the contents of this monograph collection.

  11. Closing remarks

    Indian Academy of Sciences (India)

    2007-12-12

    Dec 12, 2007 ... work with students around the world, in logging some cosmic ray data. Our hope is that in the process they will get excited about new frontiers in high ... Like many in the audience, my own personal love affair with the linear .... plea from the γγ community to the GDE and all the rest is to keep this option.

  12. Opening remarks

    Energy Technology Data Exchange (ETDEWEB)

    Foster, B. [Coal Association of Canada, Calgary, AB (Canada)

    2006-07-01

    There has been recent increased interest in the development of and investment in the Canadian coal industry because of rising natural gas prices and increased demand for coking coal. Several new Canadian producers have commenced mining and shipping coal. Premium hard coking coal prices have risen, from $40 US in 2000 to above $100 US per tonne in 2006. The resource sector is challenged by higher energy costs, increasing transportation costs, problems with equipment and parts procurement, and the recruitment and retention of skilled mining employees. Mineral exploration and development has risen seven-fold in British Columbia since 2001, where the province now offers a competitive business and taxation environment as an incentive to resource development. Coal represents 40% of British Columbia's mining revenue.

  13. Summary of remarks and recommendations concerning the 2nd draft revision of the IAEA transport regulations

    International Nuclear Information System (INIS)

    The report contains a summary of all the remarks and recommendations that had been received by the International Atomic Energy Agency from Member States and International Organizations on the second draft revision of the IAEA transport regulations

  14. Academy of Program/Project & Engineering Leadership: Shared Voyage: Learning and Unlearning from Remarkable Projects

    Data.gov (United States)

    National Aeronautics and Space Administration — Shared Voyage is about four remarkable projects:the Advanced Composition Explorer (NASA), the Joint Air-to-Surface Standoff Missile (U.S. Air Force), the Pathfinder...

  15. Remarkable long-range-systematic in the binding energies of α-nuclei. II

    International Nuclear Information System (INIS)

    Gross, D.H.E.

    2003-01-01

    In this Letter I present further data that show the remarkable evidence for the existence of an α-cluster structure in the ground states of even-even N=Z nuclei. Such a remarkable systematic was observed 20 years ago Gross and Nemes [Phys. Lett. B 130 (1983) 131] for these nuclei at A≤72 and is extended here up to A=100

  16. Diversity in viral anti-PKR mechanisms: a remarkable case of evolutionary convergence.

    Directory of Open Access Journals (Sweden)

    Elena Domingo-Gil

    Full Text Available Most viruses express during infection products that prevent or neutralize the effect of the host dsRNA activated protein kinase (PKR. Translation of Sindbis virus (SINV mRNA escapes to PKR activation and eIF2 phosphorylation in infected cells by a mechanism that requires a stem loop structure in viral 26S mRNA termed DLP to initiate translation in the absence of functional eIF2. Unlike the rest of viruses tested, we found that Alphavirus infection allowed a strong PKR activation and eIF2α phosphorylation in vitro and in infected animals so that the presence of DLP structure in mRNA was critical for translation and replication of SINV. Interestingly, infection of MEFs with some viruses that express PKR inhibitors prevented eIF2α phosphorylation after superinfection with SINV, suggesting that viral anti-PKR mechanisms could be exchangeable. Thus, translation of SINV mutant lacking the DLP structure (ΔDLP in 26S mRNA was partially rescued in cells expressing vaccinia virus (VV E3 protein, a known inhibitor of PKR. This case of heterotypic complementation among evolutionary distant viruses confirmed experimentally a remarkable case of convergent evolution in viral anti-PKR mechanisms. Our data reinforce the critical role of PKR in regulating virus-host interaction and reveal the versatility of viruses to find different solutions to solve the same conflict.

  17. Remarkable separability of the circulation response to Arctic sea ice loss and greenhouse gas forcing

    Science.gov (United States)

    McCusker, K. E.; Kushner, P. J.; Fyfe, J. C.; Sigmond, M.; Kharin, V. V.; Bitz, C. M.

    2017-12-01

    Arctic sea ice loss has an important effect on local climate through increases in ocean to atmosphere heat flux and associated feedbacks, and may influence midlatitude climate by changing large-scale circulation that can enhance or counter changes that are due to greenhouse gases. The extent to which climate change in a warming world can be understood as greenhouse gas-induced changes that are modulated by Arctic sea ice loss depends on how additive the responses to the separate influences are. Here we use a novel sea ice nudging methodology in the Canadian Earth System Model, which has a fully coupled ocean, to isolate the effects of Arctic sea ice loss and doubled atmospheric carbon dioxide (CO2) to determine their additivity and sensitivity to mean state. We find that the separate effects of Arctic sea ice loss and doubled CO2 are remarkably additive and relatively insensitive to mean climate state. This separability is evident in several thermodynamic and dynamic fields throughout most of the year, from hemispheric to synoptic scales. The extent to which the regional response to sea ice loss sometimes agrees with and sometimes cancels the response to CO2 is quantified. In this model, Arctic sea ice loss enhances the CO2-induced surface air temperature changes nearly everywhere and zonal wind changes over the Pacific sector, whereas sea ice loss counters CO2-induced sea level pressure changes nearly everywhere over land and zonal wind changes over the Atlantic sector. This separability of the response to Arctic sea ice loss from the response to CO2 doubling gives credence to the body of work in which Arctic sea ice loss is isolated from the forcing that modified it, and might provide a means to better interpret the diverse array of modeling and observational studies of Arctic change and influence.

  18. The friction coefficient of shoulder joints remains remarkably low over 24 h of loading.

    Science.gov (United States)

    Jones, Brian K; Durney, Krista M; Hung, Clark T; Ateshian, Gerard A

    2015-11-05

    The frictional response of whole human joints over durations spanning activities of daily living has not been reported previously. This study measured the friction of human glenohumeral joints during 24 h of reciprocal loading in a pendulum testing device, at moderate (0.2 mm/s, 4320 cycles) and low (0.02 mm/s, 432 cycles) sliding speeds, under a 200 N load. The effect of joint congruence was also investigated by testing human humeral heads against significantly larger mature bovine glenoids. Eight human joints and six bovine joints were tested in four combinations: human joints tested at moderate (hHCMS, n=6) and low speed (hHCLS, n=3), human humeral heads tested against bovine glenoids at moderate speed (LCMS, n=3), and bovine joints tested at moderate speed (bHCMS, n=3). In the first half hour the mean±standard deviation of the friction coefficient was hHCMS: 0.0016±0.0011, hHCLS: 0.0012±0.0002, LCMS: 0.0008±0.0002 and bHCMS: 0.0024±0.0008; in the last four hours it was hHCMS: 0.0057±0.0025, hHCLS: 0.0047±0.0017, LCMS: 0.0012±0.0003 and bHCMS: 0.0056±0.0016. The initial value was lower than the final value (pfriction coefficient of natural human shoulders remains remarkably low (averaging as little as 0.0015 and no greater than 0.006) for up to 24 h of continuous loading. The sustained low friction coefficients observed in incongruent joints (~0.001) likely represent rolling rather than sliding friction. Copyright © 2015. Published by Elsevier Ltd.

  19. The Friction Coefficient of Shoulder Joints Remains Remarkably Low Over 24 h of Loading

    Science.gov (United States)

    Jones, Brian K.; Durney, Krista M.; Hung, Clark T.; Ateshian, Gerard A.

    2015-01-01

    The frictional response of whole human joints over durations spanning activities of daily living has not been reported previously. This study measured the friction of human glenohumeral joints during 24 h of reciprocal loading in a pendulum testing device, at moderate (0.2 mm/s, 4320 cycles) and low (0.02 mm/s, 432 cycles) sliding speeds, under a 200 N load. The effect of joint congruence was also investigated by testing human humeral heads against significantly larger mature bovine glenoids. Six human joints and six bovine joints were tested in four combinations: human joints tested at moderate (hHCMS, n=6) and low speed (hHCLS, n=3), human humeral heads tested against bovine glenoids at moderate speed (LCMS, n=3), and bovine joints tested at moderate speed (bHCMS, n=3). In the first half hour the mean ± standard deviation of the friction coefficient was hHCMS: 0.0016±0.0011, hHCLS: 0.0012±0.0002, LCMS: 0.0008±0.0002 and bHCMS: 0.0024±0.0008; in the last four hours it was hHCMS: 0.0057±0.0025, hHCLS: 0.0047±0.0017, LCMS: 0.0012±0.0003 and bHCMS: 0.0056±0.0016. The initial value was lower than the final value (pfriction coefficient of natural human shoulders remains remarkably low (averaging as little as 0.0015 and no greater than 0.006) for up to 24 h of continuous loading. The sustained low friction coefficients observed in incongruent joints (~0.001) likely represent rolling rather than sliding friction. PMID:26472306

  20. Genetic background of Prop1(df) mutants provides remarkable protection against hypothyroidism-induced hearing impairment.

    Science.gov (United States)

    Fang, Qing; Giordimaina, Alicia M; Dolan, David F; Camper, Sally A; Mustapha, Mirna

    2012-04-01

    Hypothyroidism is a cause of genetic and environmentally induced deafness. The sensitivity of cochlear development and function to thyroid hormone (TH) mandates understanding TH action in this sensory organ. Prop1(df) and Pou1f1(dw) mutant mice carry mutations in different pituitary transcription factors, each resulting in pituitary thyrotropin deficiency. Despite the same lack of detectable serum TH, these mutants have very different hearing abilities: Prop1(df) mutants are mildly affected, while Pou1f1(dw) mutants are completely deaf. Genetic studies show that this difference is attributable to the genetic backgrounds. Using embryo transfer, we discovered that factors intrinsic to the fetus are the major contributor to this difference, not maternal effects. We analyzed Prop1(df) mutants to identify processes in cochlear development that are disrupted in other hypothyroid animal models but protected in Prop1(df) mutants by the genetic background. The development of outer hair cell (OHC) function is delayed, but Prestin and KCNQ4 immunostaining appear normal in mature Prop1(df) mutants. The endocochlear potential and KCNJ10 immunostaining in the stria vascularis are indistinguishable from wild type, and no differences in neurofilament or synaptophysin staining are evident in Prop1(df) mutants. The synaptic vesicle protein otoferlin normally shifts expression from OHC to IHC as temporary afferent fibers beneath the OHC regress postnatally. Prop1(df) mutants exhibit persistent, abnormal expression of otoferlin in apical OHC, suggesting delayed maturation of synaptic function. Thus, the genetic background of Prop1(df) mutants is remarkably protective for most functions affected in other hypothyroid mice. The Prop1(df) mutant is an attractive model for identifying the genes that protect against deafness.

  1. Remarks on the thermopreferendum of palearctic bats in their natural habitats

    NARCIS (Netherlands)

    Gaisler, Jiří

    1970-01-01

    This contribution comprises two remarks of ecological rather than physiological character. Contrary to Herter (1952), Herreid (1967), and Harmata (1969), I did not examine the temperature preference, or thermopreferendum, of bats under experimental conditions but concluded on it only on grounds of

  2. Remarks on an equation common to Weyl's gauge field, Yang-Mills field and Toda lattice

    International Nuclear Information System (INIS)

    Nishioka, M.

    1984-01-01

    In this letter a remark is presented on an equation of a gauge-invariant Weyl's gauge field and it is shown that the equation is common to Yang's approach to the self-duality condition for SU 2 gauge field and the simplest Toda lattice

  3. Rotational bands in the nuclear sup(168)Er and some remarks on their interpretation

    International Nuclear Information System (INIS)

    Davidson, W.F.; Dixon, W.R.; Storey, R.S.

    1984-01-01

    Further analysis of previously published data on sup(168)Er, together with results of new measurements of selected portions of the neutron capture γ-ray spectrum, has resulted in the construction of an improved level spectrum for this nucleus. Altogether 127 excited levels have now been established and grouped into 36 rotational bands. Some remarks on their interpretation are advanced

  4. Closing remarks at 4th NuFact '02 workshop, London, England, 6 July 2002

    International Nuclear Information System (INIS)

    Sessler, Andrew M.

    2003-01-01

    A brief survey is given of actual R and D activities around the world. Following that, various conceptual developments significant to factories are reviewed. Then we turn to the costs of a factory. We discuss the present budgetary woes throughout the world and end with some closing remarks

  5. A global first integral for certain dynamical systems and related remarks

    International Nuclear Information System (INIS)

    Gonzalez-Gascon, F.

    1977-01-01

    A global first integral for certain dynamical systems and the related remarks are presented. In particular, it is shown that for these dynamical systems by introducing the (intrinsic) definition of the divergence of a vector field defined on an orientable differentiable manifold, the first integral, i.e. the (intrinsic) divergence of a vector field is now, automatically, a global first integral. (author)

  6. Remark on the gravitational field produced by an infinite straight string

    International Nuclear Information System (INIS)

    Francisco, G.; Matsas, G.E.A.

    1989-01-01

    The results predicted by Newtonian gravity and general relativity are compared regarding the field produced by an infinite gauge string with constant density λ. A simple gedankenexperiment is suggested to stress the remarkable differences between these two theories. The existence of the usual Newtonian limit is discussed in this case

  7. Remarks on the high-energy behavior of string scattering amplitudes in warped spacetimes. II

    International Nuclear Information System (INIS)

    Andreev, Oleg

    2005-01-01

    We study the Regge limit of string amplitudes within the model of Polchinski-Strassler for string scattering in warped spacetimes. We also present some numerical estimations of the Regge slopes and intercepts. It is quite remarkable that the real values of those are inside a range of ours

  8. Teachers' Remarks about Their Salaries in 1800 in the Helvetic Republic

    Science.gov (United States)

    Brühwiler, Ingrid

    2015-01-01

    For centuries, teachers have complained about their salaries. In the Stapfer inquiry of 1799, some teachers made remarks about financial issues, particularly their low incomes. This inquiry is the main source for the arguments presented here regarding teachers' low salary during this period of the Helvetic Republic. The disparity between the…

  9. Opening remarks; special session 4. Burning issues and smoke screens: heat and light in southern forests

    Science.gov (United States)

    Peter J. Roussopoulos

    1998-01-01

    In Roussopoulos’ opening remarks he included nine assertions about southern forests: 1) that their characteristics are unique; 2) that they recovered from abusive agricultural practices and exploitive forest extraction in the 19th and early 20th centuries; 3) that they are brand new; 4) that social forces driving change will intensify at all scales; 5) that the...

  10. The Public University in South Africa: Philosophical Remarks on the Notion of "Elitist Knowledge" Production

    Science.gov (United States)

    Waghid, Yusef

    2009-01-01

    In my remarks about elitist knowledge production, I firstly try to adjust the perspective from which the university could be analysed; I specifically explore the functions of the university in relation to Habermas's categorisation of knowledge. Secondly, with reference to Derrida's reflections on the university, I reformulate a conception of the…

  11. Exploring the Role of Conventionality in Children's Interpretation of Ironic Remarks

    Science.gov (United States)

    Burnett, Debra L.

    2015-01-01

    Irony comprehension in seven- and eight-year-old children with typically developing language skills was explored under the framework of the graded salience hypothesis. Target ironic remarks, either conventional or novel/situation-specific, were presented following brief story contexts. Children's responses to comprehension questions were used to…

  12. A Brief History of the Most Remarkable Numbers "e," "i" and "?" in Mathematical Sciences with Applications

    Science.gov (United States)

    Debnath, Lokenath

    2015-01-01

    This paper deals with a brief history of the most remarkable Euler numbers "e,"?"i"?and?"?" in mathematical sciences. Included are many properties of the constants "e,"?"i"?and?"?" and their applications in algebra, geometry, physics, chemistry, ecology, business and industry. Special…

  13. Global checklist of species of Grania (Clitellata: Enchytraeidae with remarks on their geographic distribution

    Directory of Open Access Journals (Sweden)

    Alessandro Prantoni

    2017-12-01

    Full Text Available A checklist of all currently accepted species of Grania Southern, 1913 (Annelida, Clitellata, Enchytraeidae is presented. The genus is widespread over the world and comprises 81 species described to date. Remarks on their geographical distribution, habitat, synonymies and museum catalogue numbers are provided.

  14. Terahertz radiation generation by lasers with remarkable efficiency in electron–positron plasma

    International Nuclear Information System (INIS)

    Malik, Hitendra K.

    2015-01-01

    Photo-mixing of spatial-super-Gaussian lasers and electron–positron plasma are proposed for realizing a large amplitude nonlinear current in order to generate an efficient terahertz radiation. An external magnetic field together with a proper index of the lasers helps achieving controllable current and hence, the focused radiation of tunable frequency and power along with a remarkable efficiency of the scheme as ∼6%. - Highlights: • First proposal of photo-mixing of spatial-super-Gaussian (SSG) lasers in electron–positron (e–p) plasma. • Large amplitude nonlinear current due to the contribution of both the plasma species. • Magnetic field as an additional parameter for tunable THz radiation with a remarkable efficiency of ∼6%.

  15. Electroweak interactions at the SSC: introductory remarks multi W and Z production

    International Nuclear Information System (INIS)

    Gaillard, M.K.

    1984-03-01

    This report is a partial summary of the work of the electroweak interaction study group at the Workshop on p anti p Options for the Super Collider, University of Chicago, February 13-17, 1984. Included are general remarks concerning the topics studied and a discussion of multi intermediate vector boson production as a probe of the gauge and scalar sectors of the electroweak theory

  16. The Diamond Light Source and the challenges ahead for structural biology: some informal remarks.

    Science.gov (United States)

    Ramakrishnan, V

    2015-03-06

    The remarkable advances in structural biology in the past three decades have led to the determination of increasingly complex structures that lie at the heart of many important biological processes. Many of these advances have been made possible by the use of X-ray crystallography using synchrotron radiation. In this short article, some of the challenges and prospects that lie ahead will be summarized. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  17. Cyclodextrin-Scaffolded Alamethicin with Remarkably Efficient Membrane Permeabilizing Properties and Membrane Current Conductance

    DEFF Research Database (Denmark)

    Hjørringgaard, Claudia Ulrich; Vad, Brian Stougaard; Matchkov, Vladimir

    2012-01-01

    Bacterial resistance to classical antibiotics is a serious medical problem, which continues to grow. Small antimicrobial peptides represent a potential solution and are increasingly being developed as novel therapeutic agents. Many of these peptides owe their antibacterial activity to the formati......-channel current measurements, the α-helices of the templated multimers were demonstrated to insert into lipid bilayers forming highly efficient and remarkably stable ion-channels...

  18. Remarkable biomimetic chemoselective aerobic oxidation of flavano-ellagitannins found in oak-aged wine.

    Science.gov (United States)

    Petit, Emilie; Lefeuvre, Dorothée; Jacquet, Rémi; Pouységu, Laurent; Deffieux, Denis; Quideau, Stéphane

    2013-10-25

    Under the auspices of Bacchus! Acutissimins, natural flavano-ellagitannins, occur in oak-aged wine as a result of a diastereoselective condensation reaction of the flavan-3-ol catechin, a component of grapes, with the C-glucosidic ellagitannin vescalagin, found in oak. The acutissimins are further converted into natural mongolicains and analogues of camelliatannin G in a remarkably chemoselective fashion by simple aerobic oxidation. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. A REMARKABLE CLADONIACEAE FLORA AT SUBANDEAN REGION IN CHÁMEZA (CASANARE, COLOMBIA

    Directory of Open Access Journals (Sweden)

    LADY JOHANNA HERRERA VARGAS

    2014-12-01

    Full Text Available A remarkable Cladoniaceae flora was discovered in the subandean region of Chámeza, ( Casanare, Colombia at 1200 meters above sea level. Four species of the genus Cladonia (Cladoniaceae, Lichenized Fungi are new records for Colombia : Cladonia macilentoides, C. scabriuscula, C. sipmanii and C. subdelicatula. This shows the importance of increasing diversity studies at mid elevations where suitable habitats for species of Cladonia occur.

  20. Some remarks on theological thought of María Zambrano

    Directory of Open Access Journals (Sweden)

    Juana Sánchez-Gey Venegas

    2018-01-01

    Full Text Available Maria Zambrano reflects upon some of the problems she has been always interested in: Christianity and Mysticism with especial emphasis on the divine processions, the Incarnation of Christ, the Virgin Mary, the liturgy among other personal experiences. In these letters the pursuit for the Holy Spirit as the foundation of knowledge is remarkably noticeable, so that it could be argued that this experience contributes and gives rise to the rejection both of rationalism and of materialism of the philosophy.

  1. In quest of a relativistic constituent quark model - some constructive remarks

    International Nuclear Information System (INIS)

    Hofsaess, T.; Schierholz, G.

    1978-01-01

    The set-up of a relativistic constituent quark model in four dimensions is one of the outstanding problems in particle physics. For the time being this involves a great deal of model building which, very probably, will not change in the near future. In this paper we shall offer some general remarks which might help putting such models into shape. Most of the earlier attempts are found controversial. In particular, a conventional quark constituent interpretation could not be recovered. (orig.) [de

  2. Remarkable Improvement of Nail Changes in Alopecia Areata Universalis with 10 Months of Treatment with Tofacitinib: A Case Report

    Directory of Open Access Journals (Sweden)

    Sineida Berbert Ferreira

    2016-10-01

    Full Text Available Alopecia areata (AA is a chronic, autoimmune disease. The main symptom is massive hair loss, localized or diffuse, in the scalp and the whole body. However, nails may also be involved, and brittleness, fragility and pitting can be signs of nail dystrophy in AA patients. Here, we report the case of a male patient with AA refractory to various treatments, including oral, topical and intralesional corticosteroids, immunosuppressants, cyclosporin and PUVA (oxoralen plus ultraviolet light, all interrupted due to side effects. The patient’s nails had erythematous blotches (striated lunulae with regular and superficial pitting as well as fragility (trachyonychia, and he could no longer play the guitar because of these symptoms. With patient consent, we introduced tofacitinib (5 mg twice daily, which resulted in remarkable improvements not only regarding hair regrowth but also nail changes, with function recovery within 10 months.

  3. Characterization of remarkable floods in France, a transdisciplinary approach applied on generalized floods of January 1910

    Science.gov (United States)

    Boudou, Martin; Lang, Michel; Vinet, Freddy; Coeur, Denis

    2014-05-01

    The 2007 Flood Directive promotes the integration and valorization of historical and significant floods in flood risk management (Flood Directive Text, chapter II, and article 4). Taking into account extreme past floods analysis seems necessary in the mitigation process of vulnerability face to flooding risk. In France, this aspect of the Directive was carried out through the elaboration of Preliminary Flood Risk Assessment (PFRA) and the establishment of a 2000 floods list. From this first list, a sample of 176 floods, considered as remarkable has been selected. These floods were compiled in discussion with local authorities in charge of flood management (Lang et al., 2012) and have to be integrated in priority in local risk management policies. However, a consideration emerges about this classification: how a remarkable flood can be defined? According which criteria can it be considered as remarkable? To answer these questions, a methodology has been established by building an evaluation grid of remarkable floods in France. The primary objective of this grid is to analyze the remarkable flood's characteristics (hydrological and meteorological characteristics, sociological- political and economic impacts), and secondly to propose a classification of significant floods selected in the 2011 PFRA. To elaborate this evaluation grid, several issues had to be taken into account. First, the objective is to allow the comparison of events from various periods. These temporal disparities include the integration of various kinds of data and point out the importance of historical hydrology. It is possible to evaluate accurately the characteristics of recent floods by interpreting quantitative data (for example hydrological records. However, for floods that occurred before the 1960's it is necessary resorting to qualitative information such as written sources is necessary (Coeur, Lang, 2008). In a second part the evaluation grid requires equitable criteria in order not to

  4. A Remarkable Collection of Rare Scriptures in a Small University Library Setting

    Directory of Open Access Journals (Sweden)

    Teresa Cardin Ellis

    2013-04-01

    Full Text Available Hardin-Simmons University was given two remarkable collections of rare Bibles and a Sefer Torah with the expressed desire of the donors for the collections to be shared with students, faculty and other constituencies of the university's Richardson Library. The library has tried to fulfill this request while attempting to preserve these treasures for future generations. As small university, without a trained archivist or preservationist, we have utilized resources outside our library and contiue to pursue sources to assist us in the maintenance of these special collections while still engaging them in the educational process.

  5. Concluding remarks and outlook: Europhysics conference on flavor-mixing in weak interactions

    International Nuclear Information System (INIS)

    Chau, L.L.

    1984-01-01

    Some comments are offered on the present knowledge of the mixing matrix of Kobayashi and Maskawa and of the dynamics of nonleptonic decay. Also, remarks are made concerning CP violation. Plans for research from 1984 to 1989 are listed briefly. The history of studies on weak interactions is briefly reviewed, and several unanswered questions are stated, such as where are the truth particles, how may they be discovered, what is the mass-generating mechanism for the gauge bosons, how many Z 0 's and W's are there, do neutrinos have mass, and how long do protons live

  6. Concluding remarks. International Conference on Nuclear Physics, Berkeley, California, August 1980

    International Nuclear Information System (INIS)

    Feshbach, H.

    1980-10-01

    Not a conference summary, these concluding remarks consider five major themes that were illuminated during the conference and the problems within them that need to be resolved in the future. The five topics considered and the following: new degrees of freedom (single-particle motion, giant resonances, nuclear molecular resonances, nuclear matter, kaon-produced hypernuclei, implications of the bag model and quantum chromodynamics), new forms of matter, new reaction mechanisms (direct vs compound-nucleus reactions, heavy-ion reactions), new aspects of the weak interactions in nuclei (weak neutral currents, P invariance), and new symmetries. 4 figures

  7. Some remarks on the specification of seismic conditions for NPPs, based on the Romanian experience

    Energy Technology Data Exchange (ETDEWEB)

    Sandi, H [INCERC Building Research Inst., Bucharest (Romania)

    1993-07-01

    Some introductory remarks are devoted to the importance of revising the level of earthquake protection of NPPs, given the new knowledge at hand. Some summary data on the seismicity of Romania are given, with emphasis on the implications of instrumental data obtained during the recent strong intermediate depth earthquake of 1986 and 1990. Some problems raised by the new data in connection with the Cernavoda NPP (currently under construction), from the viewpoint of ground and floor design conditions, are discussed. Some proposals are then presented in connection with the future activities related to the verification of NPPs of the region. (author)

  8. Some remarks on the specification of seismic conditions for NPPs, based on the Romanian experience

    International Nuclear Information System (INIS)

    Sandi, H.

    1993-01-01

    Some introductory remarks are devoted to the importance of revising the level of earthquake protection of NPPs, given the new knowledge at hand. Some summary data on the seismicity of Romania are given, with emphasis on the implications of instrumental data obtained during the recent strong intermediate depth earthquake of 1986 and 1990. Some problems raised by the new data in connection with the Cernavoda NPP (currently under construction), from the viewpoint of ground and floor design conditions, are discussed. Some proposals are then presented in connection with the future activities related to the verification of NPPs of the region. (author)

  9. A remarkable new genus of Protosmylinae (Neuroptera: Osmylidae) from late Eocene Florissant, Colorado.

    Science.gov (United States)

    Makarkin, Vladimir N

    2017-05-18

    Pseudosmylidia relicta gen. et sp. nov. (Neuroptera: Osmylidae) is described from the late Eocene of Florissant (U.S.A., Colorado). It is assigned to the subfamily Protosmylinae based on the presence of two venational features characteristic of the subfamily: most crossveins in the radial to intramedial spaces of the forewing are arranged in four gradate series, and CuP is short and simple or forked only once in the hind wing. This genus is remarkable by CuP in the forewing bearing few pectinate branches. This is the only genus of extant and Cenozoic fossil Osmylidae in which this plesiomorphic condition is retained.

  10. The remarkable convergence of skull shape in crocodilians and toothed whales.

    Science.gov (United States)

    McCurry, Matthew R; Evans, Alistair R; Fitzgerald, Erich M G; Adams, Justin W; Clausen, Philip D; McHenry, Colin R

    2017-03-15

    The striking resemblance of long-snouted aquatic mammals and reptiles has long been considered an example of morphological convergence, yet the true cause of this similarity remains untested. We addressed this deficit through three-dimensional morphometric analysis of the full diversity of crocodilian and toothed whale (Odontoceti) skull shapes. Our focus on biomechanically important aspects of shape allowed us to overcome difficulties involved in comparing mammals and reptiles, which have fundamental differences in the number and position of skull bones. We examined whether diet, habitat and prey size correlated with skull shape using phylogenetically informed statistical procedures. Crocodilians and toothed whales have a similar range of skull shapes, varying from extremely short and broad to extremely elongate. This spectrum of shapes represented more of the total variation in our dataset than between phylogenetic groups. The most elongate species (river dolphins and gharials) are extremely convergent in skull shape, clustering outside of the range of the other taxa. Our results suggest the remarkable convergence between long-snouted river dolphins and gharials is driven by diet rather than physical factors intrinsic to riverine environments. Despite diverging approximately 288 million years ago, crocodilians and odontocetes have evolved a remarkably similar morphological solution to feeding on similar prey. © 2017 The Author(s).

  11. Comprehension of direct and indirect sarcastic remarks in children and adolescents with Tourette's syndrome.

    Science.gov (United States)

    Drury, Helena; Shah, Shivani; Stern, Jeremy S; Crawford, Sarah; Channon, Shelley

    2018-05-01

    Previous research has reported that aspects of social cognition such as nonliteral language comprehension are impaired in adults with Tourette's syndrome (TS), but little is known about social cognition in children and adolescents with TS. The present study aims to evaluate a measure of sarcasm comprehension suitable for use with children and adolescents (Experiment 1), and to examine sarcasm comprehension in children and adolescents with TS-alone or TS and attention deficit hyperactivity disorder (ADHD; Experiment 2). In Experiment 1, the measure of sarcasm comprehension was found to be sensitive to differences in nonliteral language comprehension for typically-developing children aged 10 to 11 years old compared to children aged 8 to 9 years old; the older group performed significantly better on the comprehension of scenarios ending with either direct or indirect sarcastic remarks, whereas the two age groups did not differ on the comprehension of scenarios ending with sincere remarks. In Experiment 2, both the TS-alone and TS+ADHD groups performed below the level of the control participants on the comprehension of indirect sarcasm items but not on the comprehension of direct sarcasm items and sincere items. Those with TS+ADHD also performed below the level of the control participants on measures of interference control and fluency. The findings are discussed with reference to the possible contribution of executive functioning and mentalizing to the patterns of performance.

  12. Remarkable strain-induced magnetic anisotropy in epitaxial Co2MnGa (0 0 1) films

    International Nuclear Information System (INIS)

    Pechan, Michael J.; Yu, Chengtao; Carr, David; Palmstroem, Chris J.

    2005-01-01

    Remarkably large, strain-induced anisotropy is observed in the thin-film Heusler alloy Co 2 MnGa. 30 nm Co 2 MnGa (0 0 1) films have been epitaxially grown on different interlayers/substrates with varied strain, and investigated with ferromagnetic resonance. The film grown on ErAs/InGaAs/InP experiences tension strain, resulting in an out-of-plane strain-induced anisotropy (∼1.1x10 6 erg/cm 3 ) adding to the effects of shape anisotropy. In contrast, the film grown on ScErAs/GaAs, experiences a compression strain, resulting in an out-of-plane strain-induced anisotropy (∼3.3x10 6 erg/cm 3 ) which almost totally cancels the effects of shape anisotropy, thus rendering the film virtually isotropic. This results in the formation of stripe domains in remanence. In addition, small, but well-defined 2-fold and 4-fold in-plane anisotropy coexist in each sample with weak, but interesting strain dependence. Transport measurement shows small (<1%) magnetoresistance effects in the compression film, but negligible magnetoresistance in the relaxed and tension strained samples

  13. Remarks at reception for Member States, 9 December 2009, Vienna, Austria

    International Nuclear Information System (INIS)

    Amano, Y.

    2009-01-01

    Full text: Dear friends and colleagues, It is a great pleasure to have this first opportunity to welcome you all since I took up my position as Director General last week. I do not wish to spoil your evening by making a long speech. But I would like to make a few remarks highlighting the areas to which I plan to give special attention in the months and years ahead. Let me say at the outset that my key objective is to address global issues related to nuclear technology, in accordance with the Statute of the IAEA. That means working for nuclear non-proliferation, enhancing nuclear safety and security, assisting Member States in meeting their energy needs, responding to concerns about climate change, helping to ensure food security and clean water and improving health care through the application of nuclear techniques. The Agency's technical cooperation programme, which aims to make the benefits of nuclear science and technology more widely available, is important to all Member States. My intention is to continue to focus on technical cooperation so that we can more effectively meet the needs of Member States, as identified by them. In this regard, the priority is capacity-building to help countries establish their own expertise in nuclear science and technology. I am planning to pay special attention in my first year to cancer control, and, next week, I will make my first official trip as Director General to Nigeria to learn first-hand about its efforts to build an effective cancer control programme, among other issues. In January, I will use my participation in the World Economic Forum in Davos to appeal for focussed global attention on the growing cancer epidemic. In September, cancer control will be the topic of the Scientific Forum. This does not mean, of course, neglecting other areas of our work, which will receive special attention in future years. I now turn to nuclear power, which is enjoying growing acceptance as a stable and clean source of energy that can

  14. Remarkable changes in behavior and physiology of laboratory mice after the massive 2011 Tohoku earthquake in Japan.

    Science.gov (United States)

    Yanai, Shuichi; Semba, Yuki; Endo, Shogo

    2012-01-01

    A devastating earthquake and tsunami hit Japan on March 11, 2011, followed by several long and intense aftershocks. Laboratory mice housed in the Tokyo, located approximately 330 km south of this earthquake's epicenter, displayed remarkable changes in a variety of behaviors and physiological measures. Although unusual pre-earthquake behaviors have been previously reported in laboratory animals, little is known about behavioral and physiological changes that occur after a great earthquake. In the present study, the effects of Tohoku earthquake on mice behavior were investigated. "Earthquake-experienced" mice displayed a marked increase in food consumption without gaining body weight in response to the earthquake. They also displayed enhanced anxiety, and in a formal fear memory task, showed significantly greater tone- and context-dependent conditioned freezing. Water maze performance of earthquake-experienced mice showed the quicker acquisition of the task, faster swim speed and longer swim distance than the naive mice. Serum corticosterone levels were elevated compared to the naive mice, indicating that the earthquake and aftershocks were stressful for the mice. These results demonstrate that great earthquakes strongly affect mouse behaviors and physiology. Although the effects of a variety of experimental manipulations on mouse behaviors in disease models or in models of higher cognitive functions have been extensively examined, researchers need to be aware how natural phenomena, such as earthquakes and perhaps other natural environmental factors, influence laboratory animal behaviors and physiology.

  15. Remarkable changes in behavior and physiology of laboratory mice after the massive 2011 Tohoku earthquake in Japan.

    Directory of Open Access Journals (Sweden)

    Shuichi Yanai

    Full Text Available A devastating earthquake and tsunami hit Japan on March 11, 2011, followed by several long and intense aftershocks. Laboratory mice housed in the Tokyo, located approximately 330 km south of this earthquake's epicenter, displayed remarkable changes in a variety of behaviors and physiological measures. Although unusual pre-earthquake behaviors have been previously reported in laboratory animals, little is known about behavioral and physiological changes that occur after a great earthquake. In the present study, the effects of Tohoku earthquake on mice behavior were investigated. "Earthquake-experienced" mice displayed a marked increase in food consumption without gaining body weight in response to the earthquake. They also displayed enhanced anxiety, and in a formal fear memory task, showed significantly greater tone- and context-dependent conditioned freezing. Water maze performance of earthquake-experienced mice showed the quicker acquisition of the task, faster swim speed and longer swim distance than the naive mice. Serum corticosterone levels were elevated compared to the naive mice, indicating that the earthquake and aftershocks were stressful for the mice. These results demonstrate that great earthquakes strongly affect mouse behaviors and physiology. Although the effects of a variety of experimental manipulations on mouse behaviors in disease models or in models of higher cognitive functions have been extensively examined, researchers need to be aware how natural phenomena, such as earthquakes and perhaps other natural environmental factors, influence laboratory animal behaviors and physiology.

  16. Remarkable Changes in Behavior and Physiology of Laboratory Mice after the Massive 2011 Tohoku Earthquake in Japan

    Science.gov (United States)

    Yanai, Shuichi; Semba, Yuki; Endo, Shogo

    2012-01-01

    A devastating earthquake and tsunami hit Japan on March 11, 2011, followed by several long and intense aftershocks. Laboratory mice housed in the Tokyo, located approximately 330 km south of this earthquake’s epicenter, displayed remarkable changes in a variety of behaviors and physiological measures. Although unusual pre-earthquake behaviors have been previously reported in laboratory animals, little is known about behavioral and physiological changes that occur after a great earthquake. In the present study, the effects of Tohoku earthquake on mice behavior were investigated. “Earthquake-experienced” mice displayed a marked increase in food consumption without gaining body weight in response to the earthquake. They also displayed enhanced anxiety, and in a formal fear memory task, showed significantly greater tone- and context-dependent conditioned freezing. Water maze performance of earthquake-experienced mice showed the quicker acquisition of the task, faster swim speed and longer swim distance than the naive mice. Serum corticosterone levels were elevated compared to the naive mice, indicating that the earthquake and aftershocks were stressful for the mice. These results demonstrate that great earthquakes strongly affect mouse behaviors and physiology. Although the effects of a variety of experimental manipulations on mouse behaviors in disease models or in models of higher cognitive functions have been extensively examined, researchers need to be aware how natural phenomena, such as earthquakes and perhaps other natural environmental factors, influence laboratory animal behaviors and physiology. PMID:22957073

  17. On the Motivation and Foundation of Natural Time Analysis: Useful Remarks

    Science.gov (United States)

    Varotsos, Panayiotis A.; Sarlis, Nicholas V.; Skordas, Efthimios S.

    2016-08-01

    Since its introduction in 2001, natural time analysis has been applied to diverse fields with remarkable results. Its validity has not been doubted by any publication to date. Here, we indicate that frequently asked questions on the motivation and the foundation of natural time analysis are directly answered if one takes into account the following two key points that we have considered as widely accepted when natural time analysis was proposed: first, the aspects on the energy of a system forwarded by Max Planck in his Treatise on Thermodynamics; second, the theorem on the characteristic functions of probability distributions which Gauss called Ein Schönes Theorem der Wahrscheinlichkeitsrechnung (beautiful theorem of probability calculus). The case of the time series of earthquakes and of the precursory Seismic Electric Signals are discussed as typical examples.

  18. Integrity assessment of pipelines - additional remarks; Avaliacao da integridade de dutos - observacoes adicionais

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Luis F.C. [PETROBRAS S.A., Salvador, BA (Brazil). Unidade de Negocios. Exploracao e Producao

    2005-07-01

    Integrity assessment of pipelines is part of a process that aims to enhance the operating safety of pipelines. During this task, questions related to the interpretation of inspection reports and the way of regarding the impact of several parameters on the pipeline integrity normally come up. In order to satisfactorily answer such questions, the integrity assessment team must be able to suitably approach different subjects such as corrosion control and monitoring, assessment of metal loss and geometric anomalies, and third party activities. This paper presents additional remarks on some of these questions based on the integrity assessment of almost fifty pipelines that has been done at PETROBRAS/E and P Bahia over the past eight years. (author)

  19. Remarks on ''Neutrino masses and mixing angles in a predictive theory of fermion masses''

    International Nuclear Information System (INIS)

    Lavoura, L.; Silva, J.P.

    1994-01-01

    In the extension of the Dimopoulos-Hall-Raby model of the fermion mass matrices to the neutrino sector, there is an entry in the up-quark and neutrino Dirac mass matrices which can be assumed to arise from the Yukawa coupling of a 120, instead of a 10 or a 126, of SO(10). Although this assumption leads to an extra undetermined complex parameter in the model, the resulting lepton mixing matrix exhibits the remarkable feature that the ν τ does not mix with the other two neutrinos. Making a reasonable assumption about the extra parameter, we are able to fit the large-mixing-angle MSW solution of the solar-neutrino problem, and we obtain m ντ ∼10 eV, the right mass range to close the Universe. Other possibilities for explaining the solar-neutrino deficit are also discussed

  20. Some remarks on the derivability of linear nonconservative systems from a Lagrangian

    International Nuclear Information System (INIS)

    Bahar, L.Y.; Kwatny, H.G.

    1980-01-01

    In this paper the linearization of the equations governing the behavior of large-scale interconnected electric power systems is carried out. It is shown that the perturbed equations of motion represent a linear, nonconservative dynamical system with arbitrary parameter matrices. Simplified conditions for the derivability of such systems from a Lagrangian are given. First integrals are derived when a certain commutativity relation is satisfied. It is shown that previously obtained results can be recovered as special cases of the present development. An example in which independent energy-like integrals are obtained by utilizing the results of this paper is given. Finally, a remark contained in a previous paper by the authors is clarified

  1. On the remarkable spectrum of a non-Hermitian random matrix model

    International Nuclear Information System (INIS)

    Holz, D E; Orland, H; Zee, A

    2003-01-01

    A non-Hermitian random matrix model proposed a few years ago has a remarkably intricate spectrum. Various attempts have been made to understand the spectrum, but even its dimension is not known. Using the Dyson-Schmidt equation, we show that the spectrum consists of a non-denumerable set of lines in the complex plane. Each line is the support of the spectrum of a periodic Hamiltonian, obtained by the infinite repetition of any finite sequence of the disorder variables. Our approach is based on the 'theory of words'. We make a complete study of all four-letter words. The spectrum is complicated because our matrix contains everything that will ever be written in the history of the universe, including this particular paper

  2. Coastal urbanization leads to remarkable seaweed species loss and community shifts along the SW Atlantic.

    Science.gov (United States)

    Scherner, Fernando; Horta, Paulo Antunes; de Oliveira, Eurico Cabral; Simonassi, José Carlos; Hall-Spencer, Jason M; Chow, Fungyi; Nunes, José Marcos C; Pereira, Sonia Maria Barreto

    2013-11-15

    Coastal urbanization is rapidly expanding worldwide while its impacts on seaweed communities remain poorly understood. We assessed the impact of urbanization along an extensive latitudinal gradient encompassing three phycogeographical regions in the SW Atlantic. Human population density, number of dwellings, and terrestrial vegetation cover were determined for each survey area and correlated with diversity indices calculated from seaweed percent cover data. Urban areas had significantly lower calcareous algal cover (-38%), and there was significantly less carbonate in the sediment off urban areas than off reference areas. Seaweed richness averaged 26% less in urban areas than in areas with higher vegetation cover. We observed a remarkable decline in Phaeophyceae and a substantial increase of Chlorophyta in urban areas across a wide latitudinal gradient. Our data show that coastal urbanization is causing substantial loss of seaweed biodiversity in the SW Atlantic, and is considerably changing seaweed assemblages. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Carbon nanocages: a new support material for Pt catalyst with remarkably high durability.

    Science.gov (United States)

    Wang, Xiao Xia; Tan, Zhe Hua; Zeng, Min; Wang, Jian Nong

    2014-03-24

    Low durability is the major challenge hindering the large-scale implementation of proton exchange membrane fuel cell (PEMFC) technology, and corrosion of carbon support materials of current catalysts is the main cause. Here, we describe the finding of remarkably high durability with the use of a novel support material. This material is based on hollow carbon nanocages developed with a high degree of graphitization and concurrent nitrogen doping for oxidation resistance enhancement, uniform deposition of fine Pt particles, and strong Pt-support interaction. Accelerated degradation testing shows that such designed catalyst possesses a superior electrochemical activity and long-term stability for both hydrogen oxidation and oxygen reduction relative to industry benchmarks of current catalysts. Further testing under conditions of practical fuel cell operation reveals almost no degradation over long-term cycling. Such a catalyst of high activity, particularly, high durability, opens the door for the next-generation PEMFC for "real world" application.

  4. Self-study program on HTML browser--application to Clinical Nursing General Remarks Course.

    Science.gov (United States)

    Ochiai, N; Sota, Y; Ezumi, H

    1997-01-01

    We created a self-study program using HTML browser on the Clinical Nursing General Remarks Course, Eighty-three students each selected a published book on a personal history (written personal reflections from individuals who had undergone medical treatment and hospitalization), read it and submitted reports of their impressions of the histories. Their reports were arranged from a nursing perspective and entered on the home page of our college using HTML browser. We intended that the students would become more interested in reading of the personal histories, and that they would acquire new self-study skills and increase their interest in Internet through use of our program. In addition, we hoped that this program would encourage positive communication and mutual sharing of information. The students were able to easily refer to a personal history according to their interest from a nursing perspective. Therefore this program realized the mutual learning among students and other users.

  5. Concluding Remarks: The Current Status and Future Prospects for GRB Astronomy

    Science.gov (United States)

    Gehrels, Neil

    2009-01-01

    We are in a remarkable period of discovery in GRB astronomy. The current satellites including Swift, Fermi. AGILE and INTEGRAL are detecting and observing bursts of all varieties. Increasing capabilities for follow-up observations on the ground and in space are leading to rapid and deep coverage across the electromagnetic spectrum, The future will see continued operation of the current experiments and with future missions like SVOM plus possible rni_Ssions like JANUS and EXIST. An exciting expansion of capabilities is occurring in areas of gravitational waves and neutrinos that could open new windows on the GRB phenomenon. Increased IR capabilities on the ground and with missions like JWST will enable further exploration of high redshift bursts. The future is bright.

  6. Remarkable identities related to the (quantum) elliptic Calogero-Sutherland model

    International Nuclear Information System (INIS)

    Langmann, Edwin

    2006-01-01

    We present remarkable functional identities related to the elliptic Calogero-Sutherland (eCS) system. We derive them from a second quantization of the eCS model within a quantum field theory model of anyons on a circle and at finite temperature. The identities involve two eCS Hamiltonians with arbitrary and, in general, different particle numbers N and M, and a particular function of N+M variables arising as anyon correlation function of N particles and M antiparticles. In addition to identities obtained from anyons with the same statistics parameter λ, we also obtain 'dual' relations involving 'mixed' correlation functions of anyons with two different statistics parameters λ and 1/λ. We also give alternative, elementary proofs of these identities by direct computations

  7. A remarkable representation of the SO(3,2) Kac-Moody algebra

    International Nuclear Information System (INIS)

    Dobrev, V.K.; Sezgin, E.

    1990-01-01

    We construct a minimal representation of the SO(3,2) Kac-Moody algebra algebra which is based on the spin-zero singleton (the Rac) representation of SO(3,2). The representation is minimal in the sense that the central charge k of the SO(3,2) Kac-Moody algebra is chosen to take the special value of 5/2 which allows the imposition of maximum number of reducibility conditions. For the Rac, this is the unique choice for the remarkable property of maximum reducibility which is consistent with unitarity. To ensure unitarity, we furthermore impose invariance condition under the maximal compact subalgebra SO(3) x SO(2). (author). 19 refs, 1 fig

  8. Mechanism of injury and instability of cervical cord injuries without remarkable Xp evidence of injury

    International Nuclear Information System (INIS)

    Ueta, Takayoshi; Shiba, Keiichiro; Katsuki, Masaaki; Shirasawa, Kenzo; Murao, Tetsu; Mori, Eiji; Yoshimura, Toyoaki; Ishibashi, Yuichi; Ryu, Seiman

    1989-01-01

    In 27 patients with no radiographic evidence of injury, spinal cord injury was depicted as low signal intensity on MRI. In 4 patients who had spontaneous reduction of the anterior dislocation, remarkable instability was observed. Among the other 23 patients, two patients had each two injured sites, and the remaining patients had only one injuried site. Injured sites were not correlated with the development of spondylosis or the antero-posterior diameter of the spinal canal, but well correlated with ossification of the posterior longitudinal ligament. Many of the patients had surgical evidence of horizontal rupture of the anterior longitudinal ligament and intervertebral disk. In these cases, although the spinal cord was instable at the level of extension, it was stable at the level of midline flection. Excessively extended injury with no associated anterior longitudinal ligament was considered attributable to the strictured spinal canal. (Namekawa, K)

  9. REMARKS ON NEUROCONTROL OF THE HAND AND SIGNIFICANCE OF AFFERENT INPUT

    Directory of Open Access Journals (Sweden)

    Nejc Sarabon

    2004-12-01

    Full Text Available This paper outlines some remarks on our understanding of motor control of the hand. It begins with current knowledge about motor behavior of prehension movements. It further highlights the distributed nature of the control system that integrates sensory information from the periphery, existing motor memory from subcortical centers, and information from diverse primary and secondary motor as well as sensory areas. It further explains the sequential nature of the processes like decision, planning, computing, and execution involved in neurocontrol of a purposeful hand motor task. In the successive part it stresses the importance of sensory input, in particular proprioceptive, for movement setting and guidance. It concludes by pointing out research concepts used to study roles of sensory information for modulating states of neurobiological systems. Finally, a novel method of whole hand electrical stimulation, which seems promising as a tool for studying sensory-motor integration mechanisms in human’s hand, is explained and recent experimental data are provided.

  10. Bildung In A New Context In Danish University Teaching With Some Remarkable Results

    DEFF Research Database (Denmark)

    Olesen, Mogens Nørgaard

    2011-01-01

    abandoned and even abolished. This, however, has had many bad consequences such as higher rates of failure. In particular, these bad consequences have been seen very clearly at the Department og Economics. A reorganization of the teaching of mathematics at this department began in 2007 where some elemnts...... of Bildung in an new modern context were included in the lectures. This had a remarkable impact. The students became more interested and more studious. How this was practically done will be the main item of this paper and it will be shown thar Bildung is very central if we want to develop university teaching...... to such a level that the enlightenment of the academic world can continiue. Furthermore it will be shown how the new teaching practice has improved the exam results substantiously....

  11. Spectroscopic and asteroseismic analysis of the remarkable main-sequence A star KIC 11145123

    Science.gov (United States)

    Takada-Hidai, Masahide; Kurtz, Donald W.; Shibahashi, Hiromoto; Murphy, Simon J.; Takata, Masao; Saio, Hideyuki; Sekii, Takashi

    2017-10-01

    A spectroscopic analysis was carried out to clarify the properties of KIC 11145123 - the first main-sequence star with a directly measured core-to-surface rotation profile - based on spectra observed with the High Dispersion Spectrograph (HDS) of the Subaru telescope. The atmospheric parameters (Teff = 7600 K, log g = 4.2, ξ = 3.1 km s-1 and [Fe/H] = -0.71 dex), the radial and rotation velocities, and elemental abundances were obtained by analysing line strengths and fitting line profiles, which were calculated with a 1D LTE model atmosphere. The main properties of KIC 11145123 are: (1) a low [Fe/H] = -0.71 ± 0.11 dex and a high radial velocity of -135.4 ± 0.2 km s-1. These are remarkable among late-A stars. Our best asteroseismic models with this low [Fe/H] have slightly high helium abundance and low masses of 1.4 M⊙. All of these results strongly suggest that KIC 11145123 is a Population II blue straggler; (2) the projected rotation velocity confirms the asteroseismically predicted slow rotation of the star; (3) comparisons of abundance patterns between KIC 11145123 and Am, Ap, and blue stragglers show that KIC 11145123 is neither an Am star nor an Ap star, but has abundances consistent with a blue straggler. We conclude that the remarkably long 100-d rotation period of this star is a consequence of it being a blue straggler, but both pathways for the formation of blue stragglers - merger and mass loss in a binary system - pose difficulties for our understanding of the exceedingly slow rotation. In particular, we show that there is no evidence of any secondary companion star, and we put stringent limits on the possible mass of any such purported companion through the phase modulation technique.

  12. Introduction to Metagenomics at DOE JGI (Opening Remarks for the Metagenomics Informatics Challenges Workshop: 10K Genomes at a Time)

    Energy Technology Data Exchange (ETDEWEB)

    Kyrpides, Nikos [DOE JGI

    2011-10-12

    After a quick introduction by DOE JGI Director Eddy Rubin, DOE JGI's Nikos Kyrpides delivers the opening remarks at the Metagenomics Informatics Challenges Workshop held at the DOE JGI on October 12-13, 2011

  13. Remarkable reduction in the threshold voltage of pentacene-based thin film transistors with pentacene/CuPc sandwich configuration

    Directory of Open Access Journals (Sweden)

    Yi Li

    2014-06-01

    Full Text Available This study investigates the remarkable reduction in the threshold voltage (VT of pentacene-based thin film transistors with pentacene/copper phthalocyanine (CuPc sandwich configuration. This reduction is accompanied by increased mobility and lowered sub-threshold slope (S. Sandwich devices coated with a 5 nm layer of CuPc layer are compared with conventional top-contact devices, and results indicate that VT decreased significantly from −20.4 V to −0.2 V, that mobility increased from 0.18 cm2/Vs to 0.51 cm2/Vs, and that S was reduced from 4.1 V/dec to 2.9 V/dec. However, the on/off current ratio remains at 105. This enhanced performance could be attributed to the reduction in charge trap density by the incorporated CuPc layer. Results suggest that this method is simple and effectively generates pentacene-based organic thin film transistors with high mobility and low VT.

  14. Eugenol—From the Remote Maluku Islands to the International Market Place: A Review of a Remarkable and Versatile Molecule

    Directory of Open Access Journals (Sweden)

    Alvaro M. Viljoen

    2012-06-01

    Full Text Available Eugenol is a major volatile constituent of clove essential oil obtained through hydrodistillation of mainly Eugenia caryophyllata (=Syzygium aromaticum buds and leaves. It is a remarkably versatile molecule incorporated as a functional ingredient in numerous products and has found application in the pharmaceutical, agricultural, fragrance, flavour, cosmetic and various other industries. Its vast range of pharmacological activities has been well-researched and includes antimicrobial, anti-inflammatory, analgesic, anti-oxidant and anticancer activities, amongst others. In addition, it is widely used in agricultural applications to protect foods from micro-organisms during storage, which might have an effect on human health, and as a pesticide and fumigant. As a functional ingredient, it is included in many dental preparations and it has also been shown to enhance skin permeation of various drugs. Eugenol is considered safe as a food additive but due to the wide range of different applications, extensive use and availability of clove oil, it is pertinent to discuss the general toxicity with special reference to contact dermatitis. This review summarises the pharmacological, agricultural and other applications of eugenol with specific emphasis on mechanism of action as well as toxicity data.

  15. Eugenol--from the remote Maluku Islands to the international market place: a review of a remarkable and versatile molecule.

    Science.gov (United States)

    Kamatou, Guy P; Vermaak, Ilze; Viljoen, Alvaro M

    2012-06-06

    Eugenol is a major volatile constituent of clove essential oil obtained through hydrodistillation of mainly Eugenia caryophyllata (=Syzygium aromaticum) buds and leaves. It is a remarkably versatile molecule incorporated as a functional ingredient in numerous products and has found application in the pharmaceutical, agricultural, fragrance, flavour, cosmetic and various other industries. Its vast range of pharmacological activities has been well-researched and includes antimicrobial, anti-inflammatory, analgesic, anti-oxidant and anticancer activities, amongst others. In addition, it is widely used in agricultural applications to protect foods from micro-organisms during storage, which might have an effect on human health, and as a pesticide and fumigant. As a functional ingredient, it is included in many dental preparations and it has also been shown to enhance skin permeation of various drugs. Eugenol is considered safe as a food additive but due to the wide range of different applications, extensive use and availability of clove oil, it is pertinent to discuss the general toxicity with special reference to contact dermatitis. This review summarises the pharmacological, agricultural and other applications of eugenol with specific emphasis on mechanism of action as well as toxicity data.

  16. A remarkably stable TipE gene cluster: evolution of insect Para sodium channel auxiliary subunits

    Directory of Open Access Journals (Sweden)

    Li Jia

    2011-11-01

    Full Text Available Abstract Background First identified in fruit flies with temperature-sensitive paralysis phenotypes, the Drosophila melanogaster TipE locus encodes four voltage-gated sodium (NaV channel auxiliary subunits. This cluster of TipE-like genes on chromosome 3L, and a fifth family member on chromosome 3R, are important for the optional expression and functionality of the Para NaV channel but appear quite distinct from auxiliary subunits in vertebrates. Here, we exploited available arthropod genomic resources to trace the origin of TipE-like genes by mapping their evolutionary histories and examining their genomic architectures. Results We identified a remarkably conserved synteny block of TipE-like orthologues with well-maintained local gene arrangements from 21 insect species. Homologues in the water flea, Daphnia pulex, suggest an ancestral pancrustacean repertoire of four TipE-like genes; a subsequent gene duplication may have generated functional redundancy allowing gene losses in the silk moth and mosquitoes. Intronic nesting of the insect TipE gene cluster probably occurred following the divergence from crustaceans, but in the flour beetle and silk moth genomes the clusters apparently escaped from nesting. Across Pancrustacea, TipE gene family members have experienced intronic nesting, escape from nesting, retrotransposition, translocation, and gene loss events while generally maintaining their local gene neighbourhoods. D. melanogaster TipE-like genes exhibit coordinated spatial and temporal regulation of expression distinct from their host gene but well-correlated with their regulatory target, the Para NaV channel, suggesting that functional constraints may preserve the TipE gene cluster. We identified homology between TipE-like NaV channel regulators and vertebrate Slo-beta auxiliary subunits of big-conductance calcium-activated potassium (BKCa channels, which suggests that ion channel regulatory partners have evolved distinct lineage

  17. Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds

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    Petra Griekspoor

    2015-12-01

    Full Text Available Background: The zoonotic bacterium Campylobacter jejuni has a broad host range but is especially associated with birds, both domestic and wild. Earlier studies have indicated thrushes of the genus Turdus in Europe to be frequently colonized with C. jejuni, and predominately with host-associated specific genotypes. The European Blackbird Turdus merula has a large distribution in Europe, including some oceanic islands, and was also introduced to Australia by European immigrants in the 1850s. Methods: The host specificity and temporal stability of European Blackbird C. jejuni was investigated with multilocus sequence typing in a set of isolates collected from Sweden, Australia, and The Azores. Results: Remarkably, we found that the Swedish, Australian, and Azorean isolates were genetically highly similar, despite extensive spatial and temporal isolation. This indicates adaptation, exquisite specificity, and stability in time for European Blackbirds, which is in sharp contrast with the high levels of recombination and mutation found in poultry-related C. jejuni genotypes. Conclusion: The maintenance of host-specific signals in spatially and temporally separated C. jejuni populations suggests the existence of strong purifying selection for this bacterium in European Blackbirds.

  18. Remarkably Enhanced Room-Temperature Hydrogen Sensing of SnO₂ Nanoflowers via Vacuum Annealing Treatment.

    Science.gov (United States)

    Liu, Gao; Wang, Zhao; Chen, Zihui; Yang, Shulin; Fu, Xingxing; Huang, Rui; Li, Xiaokang; Xiong, Juan; Hu, Yongming; Gu, Haoshuang

    2018-03-23

    In this work, SnO₂ nanoflowers synthesized by a hydrothermal method were employed as hydrogen sensing materials. The as-synthesized SnO₂ nanoflowers consisted of cuboid-like SnO₂ nanorods with tetragonal structures. A great increase in the relative content of surface-adsorbed oxygen was observed after the vacuum annealing treatment, and this increase could have been due to the increase in surface oxygen vacancies serving as preferential adsorption sites for oxygen species. Annealing treatment resulted in an 8% increase in the specific surface area of the samples. Moreover, the conductivity of the sensors decreased after the annealing treatment, which should be attributed to the increase in electron scattering around the defects and the compensated donor behavior of the oxygen vacancies due to the surface oxygen adsorption. The hydrogen sensors of the annealed samples, compared to those of the unannealed samples, exhibited a much higher sensitivity and faster response rate. The sensor response factor and response rate increased from 27.1% to 80.2% and 0.34%/s to 1.15%/s, respectively. This remarkable enhancement in sensing performance induced by the annealing treatment could be attributed to the larger specific surface areas and higher amount of surface-adsorbed oxygen, which provides a greater reaction space for hydrogen. Moreover, the sensors with annealed SnO₂ nanoflowers also exhibited high selectivity towards hydrogen against CH₄, CO, and ethanol.

  19. Exercise is medicine: some cautionary remarks in principle as well as in practice.

    Science.gov (United States)

    Neville, Ross D

    2013-08-01

    On the basis of extensive research on the relationship between physical activity, exercise and health, as well as strong support from policymakers and practitioners, the "Exercise is Medicine" initiative has become something of a linchpin in the agenda for modern healthcare reform and reflects a broader acceptance that the philosophy of health politics must shift from social engineering to performativity. However, in spite of the avowed commitment to encouraging individuals to take on a more reflexive relation to their health, it remains unclear as to whether an initiative such as this is, unambiguously, a good thing. In this paper, a number of cautionary remarks are made with respect to "Exercise is Medicine" in principle as well as in practice. Firstly, it is argued that equating exercise with medicine is to equate it with a definition of and relation to the body to which it is not entirely akin. And secondly, it is argued that any proposed alignment of the fitness and healthcare industries needs further critical examination, a realigning of interests, and a thorough reconsideration of their suitability of fit.

  20. Remarks on Correlations and Implications of the Mandibular Structure and Diet in Some Seals (Mammalia, Phocidae

    Directory of Open Access Journals (Sweden)

    Koretsky I.A.

    2014-07-01

    Full Text Available Remarks on Correlations and Implications of the Mandibular Structure and Diet in Some Seals (Mammalia, Phocidae. Koretsky, I. A., Rahmat, S. J., Peters, N. — The diverse representatives of Recent seals within the three extant subfamilies (Cystophorinae, Phocinae, Monachinae of the family Phocidae exhibit dietary variations among species, feeding on invertebrates and a diversity of prey depending on the season and availability. To explain this variability, an introductory morphological examination of the mandibular structure of Recent seals from each subfamily was performed, focusing on: heights of the mandibular ramus and condyloid process; measurements of the masseteric fossa; and attachments of muscles of mastication. After measuring the condyloid angles (the inclination of the condyloid process in relation to the axis of the alveolar row among the examined species, a correlation between the size ofthe angle, function, and diet was recognized. Seals with a tall mandibular ramus and greater condyloid angle (Cystophorinae feed on larger-sized prey, while seals with a shorter ramus and lesser condyloid angle feed on small (Monachinae to medium-sized (Phocinae prey, regardless of the overall size of the seal. This study focused on the mandibular morphology of some living and fossil representatives of Phocidae, providing an association between functional and ecological interpretations of modern seals in general and extrapolating this knowledge for fossil dietary preference.

  1. Atoms in Flight: The Remarkable Connections between Atomic and Hadronic Physics

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, Stanley J.; /SLAC

    2012-02-16

    Atomic physics and hadron physics are both based on Yang Mills gauge theory; in fact, quantum electrodynamics can be regarded as the zero-color limit of quantum chromodynamics. I review a number of areas where the techniques of atomic physics provide important insight into the theory of hadrons in QCD. For example, the Dirac-Coulomb equation, which predicts the spectroscopy and structure of hydrogenic atoms, has an analog in hadron physics in the form of light-front relativistic equations of motion which give a remarkable first approximation to the spectroscopy, dynamics, and structure of light hadrons. The renormalization scale for the running coupling, which is unambiguously set in QED, leads to a method for setting the renormalization scale in QCD. The production of atoms in flight provides a method for computing the formation of hadrons at the amplitude level. Conversely, many techniques which have been developed for hadron physics, such as scaling laws, evolution equations, and light-front quantization have equal utility for atomic physics, especially in the relativistic domain. I also present a new perspective for understanding the contributions to the cosmological constant from QED and QCD.

  2. Among ideal and real towards the urban society some remarks on the "Statute of the City

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    Ester Limonad

    2003-06-01

    Full Text Available This paper aims to contribute to grasp urban space peculiar ways of production in Brazilian cities and the implications of the "Statute of the City" in terms of the Right to the City We understand it is necessary, then, (i first, to situate our analytical perspective in relation to the idealizations on the "Statute of the City" and the search for the ideal city. Thenceforth, (ii it will be necessary to establish some methodological parameters and to make a differentiation between the different agents and social space circuits of production - related to the different moments of the social reproduction; this will allow us. ( iii to lean over the "Statute of the City" and think about the possible consequences of its implementation and what could have been, if there were no vetoes and amendments. And, (iv to conclude we will make some theoretical first remarks, based on the contributions of Lefebvre, which allow us to locate, although in a provisory manner, the "Statute of the City" in relation to use value reconquering possibility and the city appropriation by its inhabitants

  3. Interpreting the Bible in the 'new' South Africa: Remarks on some problems and challenges

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    D. J. Human

    1997-12-01

    Full Text Available Interpreting the Bible in the 'new' South Africa DJ Human Department of Biblical Studies (Sec B University of Pretoria The Bible plays an important role in South African society. The interpretation of this book within or outside the Christian community has become an increaslingly major source of debate. It has been used and misused in several spheres of society. This article does not intend providing an extensive and composite picture of the problems and character of biblical hermeneutics. Nor will it attempt to elaborate on or explain the origins, development and influences of all the different her-meneutical approaches. Rather, it poses to be an introduction to a few of the problem(s encountered in the attempt to understand the Bible, especially in terms of the 'new' South Africa. Within the framework of this scope, remarks will be made regarding the challenges involved in interpreting the Bible, the role of the interpreter in the interpretation process, the varied forms of literature to be found in Scripture, and in the last instance, to take cognisance of a few methodological approaches to the text analysis of the Bible.

  4. Late brain metastases from breast cancer: clinical remarks on 11 patients and review of the literature.

    Science.gov (United States)

    Piccirilli, Manolo; Sassun, Tanya Enny; Brogna, Christian; Giangaspero, Felice; Salvati, Maurizio

    2007-01-01

    Late brain metastases from breast cancer are a rare event. Only a few cases have been reported in the English literature. The authors describe the clinical and pathological remarks, together with treatment modalities, removal extent and overall survival, of 11 patients in whom brain metastases were detected more than 10 years from the primary tumor. Between January 1997 and April 2001, we hospitalized 11 patients, all females, with a histologically proven diagnosis of brain metastasis from breast invasive ductal carcinoma. We defined 'late metastasis' as those metastases that appeared at least 10 years after the breast cancer diagnosis. The median age at the moment of brain metastasis diagnosis was 59 years (range, 47-70), with a median latency time from breast cancer diagnosis of 16 years (range, 11-30). Ten patients underwent surgery followed by adjuvant radiotherapy (whole brain radiotherapy). Two of them received, after whole brain radiotherapy, stereotaxic radio surgery treatment. One patient had stereotaxic brain biopsy, performed by neuronavigator, followed by palliative corticosteroid therapy. Median survival after brain metastasis diagnosis was 28 months (range, 3 months-4 years). Although late brain metastases are a rare event, specific neurologic symptoms and neuroradiological evidence of a cerebral neoplasm should be correlated to the presence of a cerebral metastasis, in a patient with a previous history of breast cancer. The longer latency time from breast cancer to brain metastasis could be explained by the "clonal dominance" theory and by different genetic alterations of the metastatic cell, which could influence the clinical history of the disease.

  5. Discovery of a remarkable subpulse drift pattern in PSR B0818-41

    Science.gov (United States)

    Bhattacharyya, B.; Gupta, Y.; Gil, J.; Sendyk, M.

    2007-05-01

    We report the discovery of a remarkable subpulse drift pattern in the relatively less-studied wide profile pulsar B0818-41 using high-sensitivity Giant Metrewave Radio Telescope (GMRT) observations. We find simultaneous occurrences of three drift regions with two different drift rates: an inner region with steeper apparent drift rate flanked on each side by a region of slower apparent drift rate. Furthermore, these closely spaced drift bands always maintain a constant phase relationship. Though these drift regions have significantly different values for the measured P2, the measured P3 value is the same and equal to 18.3P1. We interpret the unique drift pattern of this pulsar as being created by the intersection of our line of sight (LOS) with two conal rings on the polar cap of a fairly aligned rotator (inclination angle α ~ 11°), with an `inner' LOS geometry (impact angle ). We argue that both rings have the same values for the carousel rotation periodicity P4 and the number of sparks Nsp. We find that Nsp is 19-21 and show that it is very likely that P4 is the same as the measured P3, making it a truly unique pulsar. We present results from simulations of the radiation pattern using the inferred parameters, which support our interpretations and reproduce the average profile as well as the observed features in the drift pattern quite well.

  6. Discovery of remarkable subpulse drifting pattern in PSR B0818-41

    Science.gov (United States)

    Bhattacharyya, B.; Gupta, Y.; Gil, J.; Sendyk, M.

    The study of pulsars showing systematic subpulse drift patterns provides important clues for understanding of pulsar emission mechanism. Pulsars with wide profiles provide extra insights because of the presence of multiple drift bands (e.g PSR B0826-34). We report the discovery of a remarkable subpulse drift pattern in a relatively less studied wide profile pulsar, PSR B0818-41, using the GMRT. We find simultaneous occurrence of three drift regions with two drift rates, an inner region with steeper apparent drift rate flanked on each side by a region of slower apparent drift rate. Furthermore, the two closely spaced drift regions always maintain a constant phase relationship. These unique drift properties seen for this pulsar is very rare. We interpret that the observed drift pattern is created by intersection of our line of sight (LOS) with two conal rings in a inner LOS (negative beta) geometry. We argue that the carousel rotation periodicity (P_4) and the number of sparks (N_sp) are the same for the rings and claim that P_4 is close to the measured P_3. Based on our analysis results and interpretations, we simulate the radiation from B0818-41. The simulations support our interpretations and reproduce the average profile and the observed drift pattern. The results of our study show that PSR B0818-41 is a powerful system to explore the pulsar radio emission mechanism, the implications of which are also discussed in our work.

  7. Remarkable influence of slack on the vibration of a single-walled carbon nanotube resonator

    Science.gov (United States)

    Ning, Zhiyuan; Fu, Mengqi; Wu, Gongtao; Qiu, Chenguang; Shu, Jiapei; Guo, Yao; Wei, Xianlong; Gao, Song; Chen, Qing

    2016-04-01

    We for the first time quantitatively investigate experimentally the remarkable influence of slack on the vibration of a single-walled carbon nanotube (SWCNT) resonator with a changeable channel length fabricated in situ inside a scanning electron microscope, compare the experimental results with the theoretical predictions calculated from the measured geometric and mechanical parameters of the same SWCNT, and find the following novel points. We demonstrate experimentally that as the slack s is increased from about zero to 1.8%, the detected vibration transforms from single-mode to multimode vibration, and the gate-tuning ability gradually attenuates for all the vibration modes. The quadratic tuning coefficient α decreases linearly with when the gate voltage Vdcg is small and the nanotube resonator operates in the beam regime. The linear tuning coefficient γ decreases linearly with when Vdcg has an intermediate value and the nanotube resonator operates in the catenary regime. The calculated α and γ fit the experimental values of the even in-plane mode reasonably well. As the slack is increased, the quality factor Q of the resonator linearly goes up, but the increase is far less steep than that predicted by the previous theoretical study. Our results are important to understand and design resonators based on CNT and other nanomaterials.

  8. Microfabricated pseudocapacitors using Ni(OH)2 electrodes exhibit remarkable volumetric capacitance and energy density

    KAUST Repository

    Kurra, Narendra

    2014-09-10

    Metal hydroxide based microfabricated pseudocapacitors with impressive volumetric stack capacitance and energy density are demonstrated. A combination of top-down photolithographic process and bottom-up chemical synthesis is employed to fabricate the micro-pseudocapacitors (μ-pseudocapacitors). The resulting Ni(OH)2-based devices show several excellent characteristics including high-rate redox activity up to 500 V s-1 and an areal cell capacitance of 16 mF cm-2 corresponding to a volumetric stack capacitance of 325 F cm-3. This volumetric capacitance is two-fold higher than carbon and metal oxide based μ-supercapacitors with interdigitated electrode architecture. Furthermore, these μ-pseudocapacitors show a maximum energy density of 21 mWh cm-3, which is superior to the Li-based thin film batteries. The heterogeneous growth of Ni(OH)2 over the Ni surface during the chemical bath deposition is found to be the key parameter in the formation of uniform monolithic Ni(OH)2 mesoporous nanosheets with vertical orientation, responsible for the remarkable properties of the fabricated devices. Additionally, functional tandem configurations of the μ-pseudocapacitors are shown to be capable of powering a light-emitting diode.

  9. New URJC-1 Material with Remarkable Stability and Acid-Base Catalytic Properties

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    Pedro Leo

    2016-02-01

    Full Text Available Emerging new metal-organic structures with tunable physicochemical properties is an exciting research field for diverse applications. In this work, a novel metal-organic framework Cu(HIT(DMF0.5, named URJC-1, with a three-dimensional non-interpenetrated utp topological network, has been synthesized. This material exhibits a microporous structure with unsaturated copper centers and imidazole–tetrazole linkages that provide accessible Lewis acid/base sites. These features make URJC-1 an exceptional candidate for catalytic application in acid and base reactions of interest in fine chemistry. The URJC-1 material also displays a noteworthy thermal and chemical stability in different organic solvents of different polarity and boiling water. Its catalytic activity was evaluated in acid-catalyzed Friedel–Crafts acylation of anisole with acetyl chloride and base-catalyzed Knoevenagel condensation of benzaldehyde with malononitrile. In both cases, URJC-1 material showed very good performance, better than other metal organic frameworks and conventional catalysts. In addition, a remarkable structural stability was proven after several consecutive reaction cycles.

  10. Remarkably enhanced photocatalytic hydrogen evolution over MoS2 nanosheets loaded on uniform CdS nanospheres

    Science.gov (United States)

    Chai, Bo; Xu, Mengqiu; Yan, Juntao; Ren, Zhandong

    2018-02-01

    The MoS2/CdS composites with layered MoS2 loaded on uniform CdS nanospheres were synthesized by a two-step process combination hydrothermal and solvothermal treatments, and then applied in photocatalytic hydrogen evolution under visible light irradiation. The as-prepared samples were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectrometer (EDS), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), Raman spectra, UV-vis diffuse reflectance absorption spectra (UV-DRS), nitrogen adsorption-desorption measurement, photoluminescence spectra (PL) and photoelectrochemical tests. The effects of loading contents of MoS2 in the composites on the photocatalytic H2 evolution activity were comparatively investigated with 0.45 mol L-1 Na2S and 0.55 mol L-1 Na2SO3 as sacrificial agents. The results showed that the 5 wt% MoS2/CdS composite could achieve the highest photocatalytic H2 evolution rate of 372 μmol h-1 and apparent quantum efficiency (AQE) about 7.31% under 420 nm monochromatic light irradiation. The remarkably enhanced photocatalytic activity of MoS2/CdS composite could be attributed to the effective transfer and separation of photogenerated charge carriers, and MoS2 being as a cocatalyst to facilitating photocatalytic H2 evolution reaction. A tentative mechanism of MoS2/CdS composites as photocatalysts for H2 evolution was proposed.

  11. A remarkable story! M.C. Vos (1759–1825 in the light of his times

    Directory of Open Access Journals (Sweden)

    Benno A. Zuiddam

    2012-11-01

    Full Text Available This article established the role of the Rev. M.C. Vos (1759–1825 as an internationally oriented Pietistic minister who encouraged mission work amongst the slaves and non-Europeans in the Cape Colony. It clears up several misunderstandings about Vos’s genealogy and argues that there is no genealogical warrant to treat Vos as something else than a White, European minister and writer. His cultural setting and ancestry was that of a colonial Dutchman, although it may have been Euro-Asian to some small extent. If so, this could have predisposed him naturally to look kindly on the lot of  Bengal and Malayan slaves. The real motivating factor for Vos’s missionary endeavours was not racial, but spiritual. The promotion of the Gospel and knowledge of the Scriptures was foremost in the mind of this Dutch Reformed minister. This article argues that the Bible and divine guidance had a remarkable influence on the life and actions of M.C. Vos, to the extent that even his autobiography is marked by Biblical language. Vos is placed within the historical perspective of his times, which assists a balanced interpretation of this remarkable person and his convictions. ’n Merkwaardige verhaal! Die lewe en historiese omstandighede van M.C.Vos (1759–1825. Hierdie artikel het die historiese rol van Ds. M.C. Vos (1759–1825 vasgestel as ’n internasionale Piëtistiese wat sending bedryf het onder die slawe en nie-Europeërs aan die Kaap. Dit helder misverstande op wat ontstaan het oor die genealogie van Vos en stel dat daar geen genealogiese rede is om Vos te beskou as ’n predikant en skrywer van nie-Europese afkoms nie. Sy kultuur en voorgeslag was dié van ’n Nederlandse kolonis, hoewel daar enige Euro-Asiatiese elemente in sy genealogie mag wees. Indien dit die geval is, dan het dit bygedra tot sy natuurlike simpatie vir die lot van die Bengaalse en Maleise slawe. Hierdie artikel toon egter aan dat die motivering vir die sendingarbeid van Vos nie op

  12. Treatment of Bulbar Urethral Strictures. A Review, with Personal Critical Remarks

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    Willem Oosterlinck

    2003-01-01

    Full Text Available This is a review article on treatment of bulbar urethral strictures with personal critical remarks on newer developments. As a treatment of first intention there exists 4 options : dilatation, urethrotomy, end to end anastomosis and free graft, open urethroplasty. Success rate of dilatation and visual urethrotomy after 4 years is only 20 en 40 % respectively. Laser urethrotomy could not fulfill expectations. End to end anastomosis obtains a very high success rate but is only applicable for short strictures. Free graft urethroplasty obtains success rates of ± 80 %. There is considerable debate on the best material for grafting. Buccal mucosa graft is the new wave, but this is not based on scientific data. Whether this graft should be used dorsally or ventrally is also a point of discussion. In view of the good results published with both techniques it is probably of no importance. Intraluminal stents are not indicated for complicated cases and give only good results in those cases which can easily be treated with other techniques. Metal self-retaining urethral stent , resorbable stents and endoscopic urethroplasty is briefly discussed. Redo’s and complicated urethral strictures need often other solutions. Here skin flap from the penile skin and scrotal flap can be used. Advantages and drawbracks of both are discussed. There is still a place for two-stage procedures in complicated redo�s. The two-stage mesh-graft urethroplasty offers advantage over the use of scrotal skin. Some other rare techniques like substitution with bowel and pudendal thigh flap, to cover deep defects, are also discussed.

  13. The remarkable frequency of human immunodeficiency virus type 1 genetic recombination.

    Science.gov (United States)

    Onafuwa-Nuga, Adewunmi; Telesnitsky, Alice

    2009-09-01

    The genetic diversity of human immunodeficiency virus type 1 (HIV-1) results from a combination of point mutations and genetic recombination, and rates of both processes are unusually high. This review focuses on the mechanisms and outcomes of HIV-1 genetic recombination and on the parameters that make recombination so remarkably frequent. Experimental work has demonstrated that the process that leads to recombination--a copy choice mechanism involving the migration of reverse transcriptase between viral RNA templates--occurs several times on average during every round of HIV-1 DNA synthesis. Key biological factors that lead to high recombination rates for all retroviruses are the recombination-prone nature of their reverse transcription machinery and their pseudodiploid RNA genomes. However, HIV-1 genes recombine even more frequently than do those of many other retroviruses. This reflects the way in which HIV-1 selects genomic RNAs for coencapsidation as well as cell-to-cell transmission properties that lead to unusually frequent associations between distinct viral genotypes. HIV-1 faces strong and changeable selective conditions during replication within patients. The mode of HIV-1 persistence as integrated proviruses and strong selection for defective proviruses in vivo provide conditions for archiving alleles, which can be resuscitated years after initial provirus establishment. Recombination can facilitate drug resistance and may allow superinfecting HIV-1 strains to evade preexisting immune responses, thus adding to challenges in vaccine development. These properties converge to provide HIV-1 with the means, motive, and opportunity to recombine its genetic material at an unprecedented high rate and to allow genetic recombination to serve as one of the highest barriers to HIV-1 eradication.

  14. Conotruncal Heart Defect Repair in Sub-Saharan Africa: Remarkable Outcomes Despite Poor Access to Treatment.

    Science.gov (United States)

    Edwin, Frank; Entsua-Mensah, Kow; Sereboe, Lawrence A; Tettey, Mark M; Aniteye, Ernest A; Tamatey, Martin M; Adzamli, Innocent; Akyaa-Yao, Nana; Gyan, Kofi B; Ofosu-Appiah, Ernest; Kotei, David

    2016-09-01

    The outcome of children born with conotruncal heart defects may serve as an indication of the status of pediatric cardiac care in sub-Saharan Africa (SSA). This study was undertaken to determine the outcome of children born with conotruncal anomalies in SSA, regarding access to treatment and outcomes of surgical intervention. From our institution in Ghana, we retrospectively analyzed the outcomes of surgery, in the two-year period from June 2013 to May 2015. The birth prevalence of congenital heart defects (CHDs) in SSA countries was derived by extrapolation using an incidence of 8 per 1,000 live births for CHDs. The birth prevalence of CHDs for the 48 countries in SSA using 2013 country data was 258,875; 10% of these are presumed to be conotruncal anomalies. Six countries (Nigeria, Democratic Republic of the Congo, Ethiopia, Tanzania, Uganda, and Kenya) accounted for 53.5% of the birth prevalence. In Ghana, 20 patients (tetralogy of Fallot [TOF], 17; pulmonary atresia, 3) underwent palliation and 50 (TOF, 36; double-outlet right ventricle, 14) underwent repair. Hospital mortality was 0% for palliation and 4% for repair. Only 6 (0.5%) of the expected 1,234 cases of conotruncal defects underwent palliation or repair within two years of birth. Six countries in SSA account for more than 50% of the CHD burden. Access to treatment within two years of birth is probably <1%. The experience from Ghana demonstrates that remarkable surgical outcomes are achievable in low- to middle-income countries of SSA. © The Author(s) 2016.

  15. Methanolic Extract of Plumbago Zeylanica - A Remarkable Antibacterial Agent Against Many Human and Agricultural Pathogens

    Directory of Open Access Journals (Sweden)

    Mukesh Kumar Singh

    2017-03-01

    Full Text Available Objectives: The current investigation was carried out to determine the cytotoxic and the antimicrobial activities of methanolic extracts of Plumbago zeylanica. Methods: The stems, leaves, and whole plants were air dried and extracted with methanol by using a Soxhlet extractor for 72 hours at 55 - 60°C. The antimicrobial activities were determined from the zones of inhibition, which were measured by using the agar well diffusion method, and the cytotoxicity assays were performed using the 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assay method. Results: The methanolic extracts of the stem and the leaves of Plumbago zeylanica were tested against six bacterial species and nine fungal species, and both extracts showed antimicrobial activity in a dose-dependent manner. The leaf extract of Plumbago zeylanica showed maximum antimicrobial activity against both Staphylococcus aureus sub sp aureus and Fusarium oxysporum. The stem extract was found to be more antimicrobial against the Pseudomonas aeruginosa and the Penicillium expansum species. MTT assays were used to test the cytotoxicity of the whole plant extract in the HCT-116 and the K-562 cell lines, and that extract was shown to have weak cytotoxicity in both cell lines. Conclusion: In the present study, the methanolic stem extracts of Plumbago zeylanica were found to possess remarkable antibacterial activities against many human and agricultural pathogens. The extracts were also found to possess significant antifungal activities, but the antifungal activities were less than the antibacterial activities. Finally, the extracts were found to have weak cytotoxicities in the HCT-116 and the K-562 cell lines.

  16. Cosmological challenges in theories with extra dimensions and remarks on the horizon problem

    International Nuclear Information System (INIS)

    Chung, Daniel J. H.; Freese, Katherine

    2000-01-01

    We consider the cosmology that results if our observable universe is a 3-brane in a higher dimensional universe. In particular, we focus on the case where our 3-brane is located at the Z 2 symmetry fixed plane of a Z 2 symmetric five-dimensional spacetime, as in the Horava-Witten model compactified on a Calabi-Yau manifold. As our first result, we find that there can be substantial modifications to the standard Friedmann-Robertson-Walker (FRW) cosmology; as a consequence, a large class of such models is observationally inconsistent. In particular, any relationship between the Hubble constant and the energy density on our brane is possible, including (but not only) FRW. Generically, due to the existence of the bulk and the boundary conditions on the orbifold fixed plane, the relationship is not FRW, and hence cosmological constraints coming from big bang nucleosynthesis, structure formation, and the age of the universe difficult to satisfy. We do wish to point out, however, that some specific choices for the bulk stress-energy tensor components do reproduce normal FRW cosmology on our brane, and we have constructed an explicit example. As our second result, for a broad class of models, we find a somewhat surprising fact: the stabilization of the radius of the extra dimension and hence the four dimensional Planck mass requires unrealistic fine-tuning of the equation of state on our 3-brane. In the last third of the paper, we make remarks about causality and the horizon problem that apply to any theory in which the volume of the extra dimension determines the four-dimensional gravitational coupling. We point out that some of the assumptions that lead to the usual inflationary requirements are modified. (c) 1999 The American Physical Society

  17. A remarkably quick habituation and high use of a rope bridge by an endangered marsupial, the western ringtail possum

    Directory of Open Access Journals (Sweden)

    Kaori Yokochi

    2015-07-01

    Full Text Available Rope bridges are being increasingly installed worldwide to mitigate the negative impacts of roads on arboreal animals. However, monitoring of these structures is still limited and an assessment of factors influencing the crossing behaviours is lacking. We monitored the use of a rope bridge near Busselton, Western Australia by the endangered western ringtail possums (Pseudocheirus occidentalis in order to identify the patterns of use and factors influencing the crossings. We installed motion sensor cameras and microchip readers on the bridge to record the crossings made by individual animals, and analysed these crossing data using generalised linear models that included factors such as days since the installation of the bridge, breeding season, wind speed, minimum temperature and moonlight. Possums started investigating the bridge even before the installation was completed, and the first complete crossing was recorded only 36 days after the installation, which is remarkably sooner than arboreal species studied in other parts of Australia. The possums crossed the bridge increasingly over 270 days of monitoring at a much higher rate than we expected (8.87 ± 0.59 complete crossings per night. Possums crossed the bridge less on windy nights and warm nights probably due to the risk of being blown away and heat stress on warmer days. Crossings also decreased slightly on brighter nights probably due to the higher risk of predation. Breeding season did not influence the crossings. Pseudocheirus occidentalis habituated to the bridge very quickly, and our results demonstrate that rope bridges have a potential as an effective mitigation measure against the negative impacts of roads on this species. More studies and longer monitoring, as well as investigating whether crossing results in the restoration of gene flow are then needed in order to further assess the true conservation value of these crossing structures.

  18. Senior expert group for the review of the Agency`s programme of activities. Opening remarks by the Director General

    Energy Technology Data Exchange (ETDEWEB)

    ElBaradei, M [International Atomic Energy Agency, Vienna (Austria)

    1998-03-23

    The document reproduces the opening remarks made by the Director General of the IAEA on 23 March 1998 at the first meeting of the Senior Expert Group for the review of the Agency`s programme and activities. The Director General explains his considerations in establishing the group, and the major challenges facing the safe use of nuclear energy and technologies

  19. Senior expert group for the review of the Agency's programme of activities. Opening remarks by the Director General

    International Nuclear Information System (INIS)

    ElBaradei, M.

    1998-01-01

    The document reproduces the opening remarks made by the Director General of the IAEA on 23 March 1998 at the first meeting of the Senior Expert Group for the review of the Agency's programme and activities. The Director General explains his considerations in establishing the group, and the major challenges facing the safe use of nuclear energy and technologies

  20. Remarkable optical red shift and extremely high optical absorption coefficient of V-Ga co-doped TiO2

    Science.gov (United States)

    Deng, Quanrong; Han, Xiaoping; Gao, Yun; Shao, Guosheng

    2012-07-01

    A first attempt has been made to study the effect of codoping of transition metal and sp metal on the electronic structure and associated optical properties of TiO2, through V-Ga codoped thin films. V-Ga codoped rutile TiO2 films were fabricated on fused quartz substrates using pulsed laser ablation, followed by heat treatment at high temperatures. Gigantic redshift in the optical absorption edge was observed in V-Ga co-doped TiO2 materials, from UV to infrared region with high absorption coefficient. Through combined structural characterization and theoretical modeling, this is attributed to the p-d hybridization between the two metals. This leads to additional energy bands to overlap with the minimum of the conduction band, leading to remarkably narrowed band gap free of mid-gap states. The direct-gap of the co-doped phase is key to the remarkably high optical absorption coefficient of the coped titania.

  1. Hypothermia and near-drowning associated with life-threatening injuries: A remarkable recovery: A case report

    Directory of Open Access Journals (Sweden)

    Tariq Cachalia

    2016-08-01

    Full Text Available A young male suffered multiple severe injuries after a fall and near-drowning. On presentation to the emergency department (ED, he was in a critical and unstable condition and his chances of survival were deemed very low. This case illustrates the management of the hypothermic multi-trauma patient and the remarkable recovery made possible by a high standard of care. Keywords: Polytrauma, Shock, Hypothermia, Coagulopathy, Trauma care

  2. Paecilaema batman, a new species of Brazilian troglophilous harvestman that exhibits a remarkable color patches variation (Opiliones: Cosmetidae

    Directory of Open Access Journals (Sweden)

    Ricardo Pinto-da-Rocha

    2013-08-01

    Full Text Available A new species of harvestman, Paecilaema batman, from Brazilian limestone caves of the state of Goiás, is described, and a remarkable intraspecific color patch variation is discussed. Paecilaema batman sp. nov. differs from other species of the genus by the following combination of features: chelicera similar in both sexes; prosoma without color patches; typical color patches on area I; and area III with two high spines. The new species is considered troglophilous.

  3. Canine visceral leishmaniasis: a remarkable histopathological picture of one asymptomatic animal reported from Belo Horizonte, Minas Gerais, Brazil

    OpenAIRE

    Xavier,S.C.; Chiarelli,I.M.; Lima,W.G.; Gonçalves,R.; Tafuri,W.L.

    2006-01-01

    A remarkable histopathological picture of one asymptomatic dog naturally infected with Leishmania infantum (syn. chagasi) has been presented. Intracellular parasites were ease found in macrophages of all exanimated organs, especially in skin. Embedded paraffin tissues of liver, spleen, axillary and popliteal lymph nodes, and skin (ear, muzzle and abdomen) were stained by hematoxylin and eosin and by immunocytochemical reaction (streptoavidin-peroxidase method) to detect parasites. All organs ...

  4. SOME REMARKS ON THE RELATION OF FORMAL AND INFORMAL IN SOLVING OPTIMIZATION PROBLEMS IN THE FIELD OF AVIATION SECURITY

    Directory of Open Access Journals (Sweden)

    L. N. Elisov

    2015-01-01

    Full Text Available The paper presents the authors view and some remarks on the problem of solving optimization problems in the field of aviation security related to insurmountable difficulties of formalization and mathematical interpretation of the domain formulation of such problems. It is shown that the vast majority of these problems is related to the solution of conflicts. The theory of conflicts gives analytical solution only in the simplest cases. For the rest the use of a heuristic approach is suggested.

  5. Closing remarks at the symposium in honour of Daniel Bellus. Pharmacenter, University of Basel, February 6, 2009.

    Science.gov (United States)

    Ganter, Camille

    2010-01-01

    In the Closing Remarks at the Symposium on 'Frontiers in Bioorganic Chemistry' (Friday, February 6, 2009, Pharmacenter, University of Basel) in honour of Daniel Bellus, his arrival in Zürich in fall 1967 and especially his postdoctoral work at the Laboratorium für Organische Chemie at the Eidgenössische Technische Hochschule (ETH) in Zürich throughout the year 1967/68 were mentioned. In his most remarkable paper (published in 1969 in Helv. Chim. Acta), the photochemistry of the alpha,beta-unsaturated cyclohexenones O-acetyl-testosterone and 10-methy-delta1,9-octalon-(2) is described in detail. Change of solvent leads to lowering or increasing of the n,pi*- and (pi,pi*)-triplet energies, resulting in a crossing of the two energy levels. Personal remarks on Daniel Bellus and warmest thanks to him, to Profs. Beat Ernst and Bernd Giese (the organizers of the symposium) and to all the speakers concluded this most special event.

  6. Public meeting on radiation safety for industrial radiographerss: remarks, questions and answers at five NRC regional meetings

    International Nuclear Information System (INIS)

    1978-11-01

    Over the past several years thenumber of radiation overexposures experienced in the radiography industry has been higher than for any other single group of NRC licensees. To inform radiography licensees of NRC's concern fo these recurring overexposure incidents, NRC staff representatives met with licensees in a series of five regional meetings. At these meetings the staff presented prepared remarks and answered questions on NRC regulations and operations. The main purposes of the meetings were to express NRC's concern for the high incidence of overexposures, and to open a line of communication between the NRC and radiography licensees in an effort to achieve the common goal of improved radiation safety. The remarks presented by the staff and subjects discussed at these meetings included: the purpose, scope, findings and goals of the NRC inspection program; ways and means of incorporating safety into radiography operations; and case histories of overexposure incidents, with highlights of the causes and possible preventions. At each of the regional meetings the staff received a request for a copy of the prepared remarks and a consolidation of the questions and answers that were discussed. This document includes that information, and a copy is being provided to each organizaion or firm attending the regional meetings. Requests for other copies should be made in accordance with the directions printed inside the front cover of this document

  7. The Remarkable Changes in the Science of Subjective Well-Being.

    Science.gov (United States)

    Diener, Ed

    2013-11-01

    The science of subjective well-being (SWB) has grown dramatically in the last three decades, moving beyond the early cross-sectional surveys of the demographic correlates of SWB. Stronger methods are frequently used to study a broader set of psychological phenomena, such as the effects on SWB of adaptation, culture, personality, and genetics. One important new research finding is that SWB has beneficial effects on health and longevity, social relationships, and productivity. National accounts of SWB are being created to provide information to policy makers about the psychological well-being of citizens. The SWB accounts represent an opportunity for psychologists to demonstrate the positive effects their interventions can produce in societies. © The Author(s) 2013.

  8. Remark on the Ansatz for IR behaviour of gluon propagator in QCD

    International Nuclear Information System (INIS)

    Tran Huu Phat; Nguyen Tuan Anh.

    1996-10-01

    It is shown that if in the IR region the gluon propagator of QCD behaves like D(k) = μ 2 δ(k) then the minimum of effective potential would correspond to the vanishing value of μ in the global color symmetry model (GCS) of QCD. (author). 10 refs, 1 fig

  9. Remarks on Andreas Abegg's paper “From the Social Contract to a Social Contract Law”

    OpenAIRE

    Maurizio Borghi

    2008-01-01

    The fact that a big, tacit social contract crumbles into a multitude of tiny explicit contracts, which govern a load of social duties, relationships and behaviours, is a striking and enigmatic phenomenon. A similar Zergliederung [dissection] undoubtedly occurs in many other areas of the Law, producing the overall effect of a “law-saturated society.” However, the most relevant feature in this process is not the astonishing shift from one legal paradigm to another, but the – mostly unnoticed – ...

  10. Some remarks on the evaluation of autoradiographs by means of microdensitometer ''Scanding 3''

    International Nuclear Information System (INIS)

    Mysak, F.; Spunda, J.

    1980-01-01

    Some factors, which influence the evaluation of autoradiographs by means of microdensitometer ''Scanding 3'' are described. The effect of pixel's area (area of picture element) used for digitalization of autoradiographs was studied. Experiments were carried out to explain the phenomena which are connected with scanning of fine details of structure. Attention is drawn to the influence of quantification of the optical density during digitalization of an autoradiograph on its evaluation. (author)

  11. Seedless Synthesis of Monodispersed Gold Nanorods with Remarkably High Yield: Synergistic Effect of Template Modification and Growth Kinetics Regulation.

    Science.gov (United States)

    Liu, Kang; Bu, Yanru; Zheng, Yuanhui; Jiang, Xuchuan; Yu, Aibing; Wang, Huanting

    2017-03-08

    Gold nanorods (AuNRs) are versatile materials due to their broadly tunable optical properties associated with their anisotropic feature. Conventional seed-mediated synthesis is, however, not only limited by the operational complexity and over-sensitivity towards subtle changes of experimental conditions but also suffers from low yield (≈15 %). A facile seedless method is reported to overcome these challenges. Monodispersed AuNRs with high yield (≈100 %) and highly adjustable longitudinal surface plasmon resonance (LSPR) are reproducibly synthesized. The parameters that influence the AuNRs growth were thoroughly investigated in terms of growth kinetics and soft-template regulation, offering a better understanding of the template-based mechanism. The facile synthesis, broad tunability of LSRP, high reproducibility, high yield, and ease of scale-up make this method promising for the future mass production of monodispersed AuNRs for applications in catalysis, sensing, and biomedicine. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Equivalence of hyperfractionated and continuous brachytherapy in a rat tumor model and remarkable effectiveness when preceded by external irradiation.

    NARCIS (Netherlands)

    Veninga, T.; Visser, A.G.; Berg, A.P. van den; Hooije, C.M. van; Geel, C.A. van; Levendag, P.C.

    2001-01-01

    PURPOSE: In clinical brachytherapy, there is a tendency to replace continuous low-dose-rate (LDR) irradiation by either single-dose or fractionated high-dose-rate (HDR) irradiation. In this study, the equivalence of LDR treatments and fractionated HDR (2 fractions/day) or pulsed-dose-rate (PDR, 4

  13. Closing Remarks of the Workshop OnGlobal University System & E-Learning

    Directory of Open Access Journals (Sweden)

    Ali YAIZCI

    2007-01-01

    Full Text Available The Workshop on Global University System & E-Learning was held on the 19th of October, 2006 at TOBB Economics & Technology University. The workshop attracted around 40 people from the Ministry of Education, Turkish Satellite Corporation (TURKSAT, Anadolu University, and various academic staff from different universities in Ankara. All together, there were 8 presentations each followed by a discussion. Main contributors, their brief CV’s, and the workshop program are included in the preceding part of this document.Here, I would try to put together various important points and remarks made by the speakers according to the order in the program.The first talk was presented by Professor Tapio Varis, Acting President of GUS, about the Global University System (GUS. He started his talk by reviewing the trends of the 21st Century in terms of education and technology. He emphasized the need to humanize the globalization process by adding “solidarity”, “sprit of caring for”, and “sharing with others”. It was stated that, content development, especially for educational purposes, is a difficult issue in achieving this process. Professor Varis, declared “digital literacy” as being a right for all. He mentioned “phonetic alphabet” as a tool to alleviate the problems associated with the communication among different nationalities. He mentioned the need to exchange ideas, opinions and experience to create a successful working environment and stressed the importance of cultural issues such as quality assurance, translation and assessment. He also talked about open courseware, “education for all”, offered by MIT and UNESCO. Finally, Professor Varis summarized the mission of GUS as to offer a global quality education (described as a renaissance education program for developing countries and/or regions by taking into account cultural sensitivities.The second talk was presented by Professor Takeshi Utsumi about the Global Collaborative

  14. Remarks on Prof. Michał Kokowski’s comment about the studies into the life of Prof. Jan Czochralski (in Polish

    Directory of Open Access Journals (Sweden)

    Paweł E. TOMASZEWSKI

    2015-12-01

    Full Text Available Remarks on the critical comments regarding the contents of the paper published after the presentation delivered by the biographer of Prof. Jan Czochralski. Unfortunately, Prof. Kokowski used an incorrect historical approach to such a short paper. The remarks are presented in four main points.

  15. Benzalkonium Chloride Provides Remarkable Stability to Liquid Protein Lures for Trapping Anastrepha obliqua (Diptera: Tephritidae).

    Science.gov (United States)

    Lasa, R; Williams, T

    2017-12-05

    Hydrolyzed protein lures are widely used to monitor fruit fly pests but are rapidly degraded by microbial activity and must be replaced frequently. To improve the stability of lures, the quaternary ammonium biocide, benzalkonium chloride (BC), was evaluated in mixtures with two hydrolyzed proteins commonly used to monitor Anastrepha spp. The mean number of Anastrepha obliqua adults captured during six consecutive weeks using Captor + borax with the addition of 240 mg BC/liter, not renewed during the test, was similar to Captor + borax that was replaced at weekly intervals and was more effective than Captor + borax without BC. Numbers of A. obliqua flies captured in 30% CeraTrap diluted in water containing 240 mg BC/liter were similar to those caught in traps baited with Captor + borax or 30% CeraTrap without BC in the first 9 d of evaluation but was significantly more effective than both lures after 56 d. After >2 mo of use, 30% CeraTrap containing 240 mg BC/liter remained as effective as newly prepared 30% CeraTrap. The addition of BC to lures reduced surface tension of liquid lures by ~40-50%. However, when BC was increased to 720 mg BC/liter, only a small additional reduction in surface tension was observed and higher concentrations of BC did not increase capture rates. These findings could contribute to reduced costs for trapping networks and the development of long-lasting formulations of liquid protein lures for bait stations and mass-trapping targeted at major tephritid pests. © The Author(s) 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Plasma turbulence in the ionosphere prior to earthquakes, some remarks on the DEMETER registrations

    Science.gov (United States)

    Błęcki, Jan; Parrot, Michel; Wronowski, Roman

    2011-06-01

    The question about presence of some precursors of the earthquakes has a long history. The answer is still not resolved, but researchers are looking for the effects which can be registered prior to earthquakes. One of the factors which has been found is the variation of the electromagnetic field observed on ground as well as onboard satellites. The disturbances of the electromagnetic field around areas of the earthquakes as pre-seismic events can occur few hours or even few days before the main shock. The payload of the DEMETER French microsatellite allows to measure waves and also some important plasma parameters (ion composition, electron density and temperature, energetic particles) with high temporal resolution in the ionosphere over the seismic regions. In the present work, analysis of the low frequency fluctuations of the electric fields for selected strong earthquakes in Japan (2004), China (2008), Taiwan (2006) and New Zealand (2009) are given. Special attention will be given to the study of the spectral characteristics of these variations and the search for nonlinear effects. This analysis is possible in the time interval where the waveform has been transmitted. The mechanism of the energy transmission from earthquakes to the ionosphere is not clear, but we can discuss the behavior of the ionospheric plasma and the search for instabilities which could be a source of electromagnetic field variations. A brief discussion of the characteristics of the spectra and multi-spectra is given in this paper. Attention is particularly given to the effect prior to the earthquake in New Zealand, when a nonlinear interaction leading to a lower hybrid wave generation was directly seen.

  17. Remark on the role of the driving force in BWR instability

    International Nuclear Information System (INIS)

    Dykin, V.; Pazsit, I.

    2009-01-01

    Simple models of BWR instability, used e.g. in understanding the role of the various oscillation modes in the overall stability of the plant, assume that each oscillation mode can be described by a second order system (a damped harmonic oscillator) driven by a white noise driving force. Change of the decay ratio (DR) of the observed signal is, as a rule, associated with the changing of the parameters of the damped oscillator, mainly its damping coefficient, and is interpreted in terms of the change of the stability of the system. However, conceptually, one cannot exclude cases when the change of the response of a driven damped oscillator is due to the change of the properties of the driving force. In this work we investigate the effect of a non-white driving force on the behaviour of the system. A question of interest is how changes of the spectrum of the driving force influence the observed autocorrelation function (ACF) of the resulting signal. Hence we calculate the response of a damped harmonic oscillator driven by a non-white driving force, corresponding to the reactivity effect of propagating density fluctuations in two-phase flow. It is shown how in some special cases such a driving force, when interpreting the neutron noise as if induced by a white noise driving source, can lead to an erroneous conclusion regarding the stability of the system. It is also concluded that in the practically interesting cases the effect of the coloured driving force, arising from propagating density fluctuations, is negligible.

  18. Biotechnological Chondroitin a Novel Glycosamminoglycan With Remarkable Biological Function on Human Primary Chondrocytes.

    Science.gov (United States)

    Stellavato, Antonietta; Tirino, Virginia; de Novellis, Francesca; Della Vecchia, Antonella; Cinquegrani, Fabio; De Rosa, Mario; Papaccio, Gianpaolo; Schiraldi, Chiara

    2016-09-01

    Cartilage tissue engineering, with in vitro expansion of autologus chondrocytes, is a promising technique for tissue regeneration and is a new potential strategy to prevent and/or treat cartilage damage (e.g., osteoarthritis). The aim of this study was (i) to investigate and compare the effects of new biotechnological chondroitin (BC) and a commercial extractive chondroitin sulfate (CS) on human chondrocytes in vitro culture; (ii) to evaluate the anti-inflammatory effects of the innovative BC compared to extractive CS. A chondrogenic cell population was isolated from human nasoseptal cartilage and in vitro cultures were studied through time-lapse video microscopy (TLVM), immunohistochemical staining and cytometry. In order to investigate the effect of BC and CS on phenotype maintainance, chondrogenic gene expression of aggrecan (AGN), of the transcriptor factor SOX9, of the types I and II collagen (COL1A1 and COL1A2), were quantified through transcriptional and protein evaluation at increasing cultivation time and passages. In addition to resemble the osteoarthritis-like in vitro model, chondrocytes were treated with IL-1β and the anti-inflammatory activity of BC and CS was assessed using cytokines quantification by multiplex array. BC significantly enhances cell proliferation also preserving chondrocyte phenotype increasing type II collagen expression up to 10 days of treatment and reduces inflammatory response in IL-1β treated chondrocytes respect to CS treated cells. Our results, taken together, suggest that this new BC is of foremost importance in translational medicine because it can be applied in novel scaffolds and pharmaceutical preparations aiming at cartilage pathology treatments such as the osteoarthritis. J. Cell. Biochem. 117: 2158-2169, 2016. © 2016 The Authors. Journal of Cellular Biochemistry Published by Wiley Periodicals, Inc. © 2016 The Authors. Journal of Cellular Biochemistry Published by Wiley Periodicals, Inc.

  19. Remarks on Andreas Abegg's paper “From the Social Contract to a Social Contract Law”

    Directory of Open Access Journals (Sweden)

    Maurizio Borghi

    2008-05-01

    Full Text Available The fact that a big, tacit social contract crumbles into a multitude of tiny explicit contracts, which govern a load of social duties, relationships and behaviours, is a striking and enigmatic phenomenon. A similar Zergliederung [dissection] undoubtedly occurs in many other areas of the Law, producing the overall effect of a “law-saturated society.” However, the most relevant feature in this process is not the astonishing shift from one legal paradigm to another, but the – mostly unnoticed – emergence of the trait of functionality.

  20. The remarkable vision of Robert Hooke (1635-1703): first observer of the microbial world.

    Science.gov (United States)

    Gest, Howard

    2005-01-01

    Robert Hooke played important roles in the early development of the Royal Society of London. As Curator of Experiments of the Society, he became a pioneering microscopist, prolific inventor, astronomer, geologist, architect, and an effective surveyor of the City of London following the Great Fire of 1666. Hooke's Micrographia (1665) revealed the microscopic structures of numerous biological and inorganic objects and became an important source of information for later studies. Aside from the body of detailed observations reported and depicted in Micrographia, the Preface is in itself an extraordinary document that exhibits Hooke's fertile mind, philosophical insights, and rare ability to look into the future.

  1. Fluorination of Naturally Occurring N6-Benzyladenosine Remarkably Increased Its Antiviral Activity and Selectivity

    Directory of Open Access Journals (Sweden)

    Vladimir E. Oslovsky

    2017-07-01

    Full Text Available Recently, we demonstrated that the natural cytokinin nucleosides N6-isopentenyladenosine (iPR and N6-benzyladenosine (BAPR exert a potent and selective antiviral effect on the replication of human enterovirus 71. In order to further characterize the antiviral profile of this class of compounds, we generated a series of fluorinated derivatives of BAPR and evaluated their activity on the replication of human enterovirus 71 in a cytopathic effect (CPE reduction assay. The monofluorination of the BAPR-phenyl group changed the selectivity index (SI slightly because of the concomitant high cell toxicity. Interestingly, the incorporation of a second fluorine atom resulted in a dramatic improvement of selectivity. Moreover, N6-trifluoromethylbenzyladenosine derivatives (9–11 exhibited also a very interesting profile, with low cytotoxicity observed. In particular, the analogue N6-(3-trifluoromethylbenzyl-adenosine (10 with a four-fold gain in potency as compared to BAPR and the best SI in the class represents a promising candidate for further development.

  2. Extremophilic Acinetobacter Strains from High-Altitude Lakes in Argentinean Puna: Remarkable UV-B Resistance and Efficient DNA Damage Repair

    Science.gov (United States)

    Albarracín, Virginia Helena; Pathak, Gopal P.; Douki, Thierry; Cadet, Jean; Borsarelli, Claudio Darío; Gärtner, Wolfgang; Farias, María Eugenia

    2012-06-01

    High-Altitude Andean Lakes (HAAL) of the South American Andes are almost unexplored ecosystems of shallow lakes. The HAAL are recognized by a remarkably high UV exposure, strong changes in temperature and salinity, and a high content of toxic elements, especially arsenic. Being exposed to remarkably extreme conditions, they have been classified as model systems for the study of life on other planets. Particularly, Acinetobacter strains isolated from the HAAL were studied for their survival competence under strong UV-B irradiation. Clinical isolates, Acinetobacter baumannii and Acinetobacter johnsonii, served as reference material. Whereas the reference strains rapidly lost viability under UV-B irradiation, most HAAL-derived strains readily survived this exposure and showed less change in cell number after the treatment. Controls for DNA repair activity, comparing dark repair (DR) or photo repair (PR), gave evidence for the involvement of photolyases in the DNA repair. Comparative measurements by HPLC-mass spectrometry detected the number of photoproducts: bipyrimidine dimers under both PR and DR treatments were more efficiently repaired in the HAAL strains (up to 85 % PR and 38 % DR) than in the controls (31 % PR and zero DR ability). Analysis of cosmid-cloned total genomic DNA from the most effective DNA-photorepair strain (Ver3) yielded a gene (HQ443199) encoding a protein with clear photolyase signatures belonging to class I CPD-photolyases. Despite the relatively low sequence similarity of 41 % between the enzymes from Ver3 and from E. coli (PDB 1DNPA), a model-building approach revealed a high structural homology to the CPD-photolyase of E. coli.

  3. [Management of Personal Information in Clinical Laboratory Medicine:--Chairmen's Introductory Remarks].

    Science.gov (United States)

    Yoshida, Hiroshi; Shimetani, Naoto

    2014-11-01

    The Japanese Society of Laboratory Medicine has been running its own Medical Safety Committee, and holding a symposium on medical safety during the annual meeting. The medical world is filled with a considerable amount of personal information, including genetic information, the ultimate personal information. We, as medical staff, have to manage such personal information not only in times of peace but also during disasters or emergency situations. In Japan, the Act on the Protection of Personal Information is currently being implemented, but a number of problems remain. Human beings have entered the information technology era, including electrical medical record systems, which is useful for research and education besides medical practice. This is why personal information must be more effectively protected from leakage, misconception, and abuse. We should create a sound system to manage personal information, with the spirit of protecting patient information that originated from the Oath of Hippocrates.

  4. Remarks on the thermal stability of an Ohmic-heated nanowire

    Science.gov (United States)

    Timsit, Roland S.

    2018-05-01

    The rise in temperature of a wire made from specific materials, due to ohmic heating by a DC electrical current, may lead to uncontrollable thermal runaway with ensuing melting. Thermal runaway stems from a steep decrease with increasing temperature of the thermal conductivity of the conducting material and subsequent trapping of the ohmic heat in the wire, i.e., from the inability of the wire to dissipate the heat sufficiently quickly by conduction to the cooler ends of the wire. In this paper, we show that the theory used to evaluate the temperature of contacting surfaces in a bulk electrical contact may be applied to calculate the conditions for thermal runaway in a nanowire. Implications of this effect for electrical contacts are addressed. A possible implication for memory devices using ohmic-heated nanofilms or nanowires is also discussed.

  5. Reproductive Rights and Women’s Freedom. Remarks on the Feminist Debate

    Directory of Open Access Journals (Sweden)

    Isabel Fanlo Cortés

    2017-07-01

    Full Text Available This article seeks to contribute to the issue of reproductive rights, assuming for the analysis the perspective of the contemporary Western feminist debate. Notwithstanding the variety of approaches and positions that find expression in the scope of such a debate, emphasis is given to the convergent interest of the most recent feminist bioethical discussion in the subject of legal regulation that the States predict, both in relation to the use of certain Reproductive technologies, and the exercise of other reproductive rights, as well as the value premises that underpin these policies and their effects on the lives of women. Finally, in the light of the recent transformations of the modalities of public control over reproductive choices, some challenges will be identified that fall on contemporary feminisms.

  6. Remarks on a five-dimensional Kaluza-Klein theory of the massive Dirac monopole

    International Nuclear Information System (INIS)

    Cotaescu, Ion I.

    2005-01-01

    The Gross-Perry-Sorkin spacetime, formed by the Euclidean Taub-Newman-Unti-Tamburino space with the time trivially added, is the appropriate background of the Dirac magnetic monopole without an explicit mass term. We show that there exists a very simple five-dimensional metric of spacetimes carrying massive magnetic monopoles that is an exact solution of the vacuum Einstein equations. Moreover, the same isometry properties as the original Euclidean Taub-Newman-Unti-Tamburino space are preserved. This leads to an Abelian Kaluza-Klein theory whose metric appears as a combination between the Gross-Perry-Sorkin and Schwarzschild ones. The asymptotic motion of the scalar charged test particles is discussed, now by accounting for the mixing between the gravitational and magnetic effects

  7. Maxi-Min Language Use A Critical Remark on a Concept by Philippe van Parijs

    Directory of Open Access Journals (Sweden)

    Kruse Jan

    2016-10-01

    Full Text Available Philippe van Parijs explains in Linguistic Justice for Europe and for the World the concept of maxi-min language use as a process of language choice. He suggests that the language chosen as a common language should maximize the minimal competence of a community. Within a multilingual group of people, the chosen language is the language known best by a participant who knows it least. For obvious reasons, only English would qualify for having that status. This article argues that maxi-min is rather a normative concept, not only because the process itself remains empirically unfounded. Moreover, language choice is the result of complex social and psychological structures. As a descriptive process, the maxi-min choice happens in the reality fairly seldom, whereas the max-min use of languages seen as a normative process could be a very effective tool to measure linguistic justice.

  8. Introductory remarks by the Chairman. [Session 1: Environmental and health consequences of the Chernobyl accident

    International Nuclear Information System (INIS)

    Bennett, B.G.

    2005-01-01

    Many scientists as well as representatives from UN organizations and governments of affected regions participated in the work of the Chernobyl Forum. Several meetings of the Forum were necessary to initiate the work and monitor the progress of the expert groups. Two expert groups formulated comprehensive reports - one on environmental issues, organized by the IAEA, and one on health issues, organized by the WHO. Experts from throughout the world were invited to contribute to these evaluations. The representatives of governments and the staff of international organizations then reviewed the results of these groups to be sure that the reviews were complete and the evaluations reasonable, so that they could serve as the basis for consensus agreements and effective recommendations for further dealing with the consequences of the accident

  9. Some remarks on the time of flight and range of a projectile in a linear resisting medium

    Directory of Open Access Journals (Sweden)

    S. M. Stewart

    2011-01-01

    Full Text Available In view of the recent work by Karkantzakos [Journal of Engineering Science and Technology Review 2 (2009 76–81], anumber of remarks highlighting the connection between the Lambert W function and the time of flight and range of a projectilemoving in a resisting medium where the retarding force acting on the projectile is proportional to its velocity are made.In particular, we show how each of these quantities can be expressed in closed form in terms of the Lambert W function andindicate how the analysis of the motion becomes greatly simplified by its introduction.

  10. Axel Honneth: The law of freedom – Institutionalization of freedom in modern societies - A reconstruction and some remarks

    Directory of Open Access Journals (Sweden)

    Jacob Dahl Rendtorff

    2012-03-01

    Full Text Available This paper reconstructs the argument of Axel Honneth's recent book Das Recht der Freiheit as a theory of the institutionalization of freedom in modern society. In particular, it looks at Honneth's argument for the realization of freedom in law and morality that is proposed as a contemporary re-interpretation of Hegel's Philosophy of Right. Then I discuss Honneth's argument for the reality of freedom in the ethical spheres of civil society, in particular in the family, the market and in democracy. Finally, the paper proposes some critical remarks to Honneth's theory.

  11. Axel Honneth: The law of freedom – Institutionalization of freedom in modern societies - A reconstruction and some remarks

    DEFF Research Database (Denmark)

    Rendtorff, Jacob Dahl

    2012-01-01

    This paper reconstructs the argument of Axel Honneth's recent book Das Recht der Freiheit as a theory of the institutionalization of freedom in modern society. In particular, it looks at Honneth's argument for the realization of freedom in law and morality that is proposed as a contemporary re......-interpretation of Hegel's Philosophy of Right. Then I discuss Honneth's argument for the reality of freedom in the ethical spheres of civil society, in particular in the family, the market and in democracy. Finally, the paper proposes some critical remarks to Honneth's theory....

  12. A remarkable hematological and molecular response pattern in a patient with polycythemia vera during combination therapy with simvastatin and alendronate

    Directory of Open Access Journals (Sweden)

    Anders Lindholm Sørensen

    2016-01-01

    Full Text Available We report a 57-year old man with polycythemia vera, who had a remarkable hematological and molecular response during treatment with simvastatin and alendronate. The patient was treated with this combination for 56 months, and during this period the patient has been in complete hematological remission. The JAK2-V617F allele burden has dropped from 64% to sustained values below 20%, and follow-up bone marrow biopsies have revealed no change in PV features, without any regular cytoreductive treatment.

  13. Remarks on reporting and recording consistent with the ICRU Reference Dose

    Directory of Open Access Journals (Sweden)

    Gainey Mark

    2009-10-01

    Full Text Available Abstract Background ICRU 50/62 provides a framework to facilitate the reporting of external beam radiotherapy treatments from different institutions. A predominant role is played by points that represent "the PTV dose". However, for new techniques like Intensity Modulated Radiotherapy (IMRT - especially step and shoot IMRT - it is difficult to define a point whose dose can be called "characteristic" of the PTV dose distribution. Therefore different volume based methods of reporting of the prescribed dose are in use worldwide. Several of them were compared regarding their usability for IMRT and compatibility with the ICRU Reference Point dose for conformal radiotherapy (CRT in this study. Methods The dose distributions of 45 arbitrarily chosen volumes treated by CRT plans and 57 volumes treated by IMRT plans were used for comparison. Some of the IMRT methods distinguish the planning target volume (PTV and its central part PTVx (PTV minus a margin region of × mm. The reporting of dose prescriptions based on mean and median doses together with the dose to 95% of the considered volume (D95 were compared with each other and in respect of a prescription report with the aid of one or several possible ICRU Reference Points. The correlation between all methods was determined using the standard deviation of the ratio of all possible pairs of prescription reports. In addition the effects of boluses and the characteristics of simultaneous integrated boosts (SIB were examined. Results Two types of methods result in a high degree of consistency with the hitherto valid ICRU dose reporting concept: the median dose of the PTV and the mean dose to the central part of the PTV (PTVx. The latter is similar to the CTV, if no nested PTVs are used and no patient model surfaces are involved. A reporting of dose prescription using the CTV mean dose tends to overestimate the plateau doses of the lower dose plateaus of SIB plans. PTVx provides the possibility to approach

  14. Remarks on reporting and recording consistent with the ICRU Reference Dose

    International Nuclear Information System (INIS)

    Bratengeier, Klaus; Oechsner, Markus; Gainey, Mark; Flentje, Michael

    2009-01-01

    ICRU 50/62 provides a framework to facilitate the reporting of external beam radiotherapy treatments from different institutions. A predominant role is played by points that represent 'the PTV dose'. However, for new techniques like Intensity Modulated Radiotherapy (IMRT) - especially step and shoot IMRT - it is difficult to define a point whose dose can be called 'characteristic' of the PTV dose distribution. Therefore different volume based methods of reporting of the prescribed dose are in use worldwide. Several of them were compared regarding their usability for IMRT and compatibility with the ICRU Reference Point dose for conformal radiotherapy (CRT) in this study. The dose distributions of 45 arbitrarily chosen volumes treated by CRT plans and 57 volumes treated by IMRT plans were used for comparison. Some of the IMRT methods distinguish the planning target volume (PTV) and its central part PTV x (PTV minus a margin region of × mm). The reporting of dose prescriptions based on mean and median doses together with the dose to 95% of the considered volume (D 95 ) were compared with each other and in respect of a prescription report with the aid of one or several possible ICRU Reference Points. The correlation between all methods was determined using the standard deviation of the ratio of all possible pairs of prescription reports. In addition the effects of boluses and the characteristics of simultaneous integrated boosts (SIB) were examined. Two types of methods result in a high degree of consistency with the hitherto valid ICRU dose reporting concept: the median dose of the PTV and the mean dose to the central part of the PTV (PTV x ). The latter is similar to the CTV, if no nested PTVs are used and no patient model surfaces are involved. A reporting of dose prescription using the CTV mean dose tends to overestimate the plateau doses of the lower dose plateaus of SIB plans. PTV x provides the possibility to approach biological effects

  15. Radiation damage studies in nuclear waste storage matrices: a few remarks

    International Nuclear Information System (INIS)

    Limoge, Y.

    1997-01-01

    For safe management of high level nuclear waste (HLNW) we have to predict the behaviour of the storage matrix that will have to sustain irradiation over a long period of 10 4 to 10 5 years. 2 approaches are possible and in fact complementary. The first approach is an experimental one: the selected material is submitted to an acceleration of the damage by using various forms of external or internal radiations delivering a higher flux than the stored wastes themselves. The second approach is a cognitive one that requires the modelling of the radiation damage. The second approach seems to have been less developed than the first one. The second approach is a multi-step one. The first step is to review and model all possible phenomena occurring in irradiated material. The second step is to review the different kinds of defects produced by irradiation, their possible mutual interaction and their elimination modes that are followed by the material to go back to equilibrium. There have been a lot of detailed studies of defect formation under ionizing conditions in silica and simple silica based glass, mainly for electronic industry purposes. Fewer studies have been done on nuclear glasses. This article makes a point about the necessity and need for reliable simulation of long-term irradiation effects on nuclear glasses

  16. Fatigue assessment by the RCC-MR design rules: remarks on the elastic analysis

    International Nuclear Information System (INIS)

    Taleb, L.; Sidoroff, F.

    1999-01-01

    According to RCC--MR (French rules for mechanical engineering design of FBR), fatigue life assessment is based on the evaluation of the equivalent elastoplastic strain range resulting from a given cyclic loading. Two methods can be used according to whether an elastoplastic or an elastic structure analysis is performed. The elastic analysis is of course more attractive for it avoids a heavy iterative elastoplastic analysis and an expensive identification of the material behavior from mechanical tests. On the other hand it relies on some empirical extrapolation rules from the elastic to the real case. The purpose of the present paper is to draw attention to some limitations of this procedure. In particular attention will be focused on two points: 1, the classification of the applied stress into primary and secondary parts is essential and it is shown that the thermal stresses which are often considered as secondary may in some cases play a primary role; 2. the Neuber's rule which is used to evaluate the plastic strain from the elastic stress will be shown to be significantly wrong for some special configurations. This is in fact essentially related to situations where the elastic follow up effect is important. (authors)

  17. Remarks on the necessity and implications of state-dependence in the black hole interior

    Science.gov (United States)

    Papadodimas, Kyriakos; Raju, Suvrat

    2016-04-01

    We revisit the "state-dependence" of the map that we proposed recently between bulk operators in the interior of a large anti-de Sitter black hole and operators in the boundary CFT. By refining recent versions of the information paradox, we show that this feature is necessary for the CFT to successfully describe local physics behind the horizon—not only for single-sided black holes but even in the eternal black hole. We show that state-dependence is invisible to an infalling observer who cannot differentiate these operators from those of ordinary quantum effective field theory. Therefore the infalling observer does not observe any violations of quantum mechanics. We successfully resolve a large class of potential ambiguities in our construction. We analyze states where the CFT is entangled with another system and show that the ER =EPR conjecture emerges from our construction in a natural and precise form. We comment on the possible semiclassical origins of state-dependence.

  18. Remarks concerning the determination of burn-out in research reactors

    International Nuclear Information System (INIS)

    Fabrega, S.; Lafay, J.; Vernier, P.

    1969-01-01

    The operation of reactors cooled by water at low pressure is quite safe as long as the margin existing between nominal conditions and certain conditions leading to burn-out is known. The phenomena which can cause such an effect are defined here. A distinction is made between primary burnout, which is completely localized, and secondary burn-up. This latter can be the result either of a flow reduction, or of the onset of a hydrodynamic oscillation, or again of the attainment of sonic flow conditions. Once the planner is aware of the varied nature of these phenomena, it is shown which are the precautions to be taken during the construction and operation of an out-of-pile test-loop so that such phenomena may subsequently be detected. In the first experiment on a loop with a 600 x 53 x 2 mm rectangular channel, there resulted either primary (critical) burn-out (down-stream pressurization), or secondary critical burn-out (up-stream pressurization) resulting from instability. Another experiment has shown that in the case of the reactor PEGASE, critical burn-out was due to flow reduction in nominal and steady-state operational conditions. (authors) [fr

  19. Some Remarks on Prediction of Drug-Target Interaction with Network Models.

    Science.gov (United States)

    Zhang, Shao-Wu; Yan, Xiao-Ying

    2017-01-01

    System-level understanding of the relationships between drugs and targets is very important for enhancing drug research, especially for drug function repositioning. The experimental methods used to determine drug-target interactions are usually time-consuming, tedious and expensive, and sometimes lack reproducibility. Thus, it is highly desired to develop computational methods for efficiently and effectively analyzing and detecting new drug-target interaction pairs. With the explosive growth of different types of omics data, such as genome, pharmacology, phenotypic, and other kinds of molecular networks, numerous computational approaches have been developed to predict Drug-Target Interactions (DTI). In this review, we make a survey on the recent advances in predicting drug-target interaction with network-based models from the following aspects: i) Available public data sources and benchmark datasets; ii) Drug/target similarity metrics; iii) Network construction; iv) Common network algorithms; v) Performance comparison of existing network-based DTI predictors. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  20. Remarks relating to field experiments to measure the wet scavenging of tracer aerosols

    International Nuclear Information System (INIS)

    Stensland, G.J.

    1977-12-01

    An important question is whether or not the wet deposition of debris from a single (or multiple) airburst of a nuclear device poses a significant hazard to people on the ground. To answer this question for various scenarios, a basic understanding of the aerosol attachment rates to cloud water and raindrops is needed. The attachment rates can then be incorporated into the cloud physics scavenging models to make intelligent assessments. In order to gain an initial impression as to the importance (order of magnitude) of the wet scavenging effects and to provide the data to validate the cloud scavenging models, tracer release field experiments are useful and necessary. The major purpose of this report is to address questions related to the operation and interpretation of such field tracer efforts and in particular to consider the results from the August 3, 1972, Battelle Northwest Laboratory tracer experiment in St. Louis. The Battelle experiment involved the release of several aerosol tracers at 10,000 to 13,000 feet, near rain clouds, and the measurement of the resulting tracer in the rain collected at the ground level sampling sites

  1. [Globalization and its historical location. Some remarks with the example of Ernst Haeckel].

    Science.gov (United States)

    Breidbach, Olaf

    2014-01-01

    Globalization, regarded here as the extensive and profound transformation process of modernity, manifests itself to us in the way it impacts the here and now. However, it also has a prehistory with regard to both its anthropogenic effects on nature and intellectual controversies. This prehistory is important for understanding how we deal with this phenomenon. Due to the important roles science plays in the process of globalization and the, in no way insignificant, repercussions it has on the sciences themselves, this article aims to present in detail a prehistory that pointedly illustrates how we perceive our modernity, also with regard to its discrepancies which result from the various underlying conditions. In its attempt to analyze the question of contemporary perception in an exemplary way, the article below looks back at the intellectual situation prevailing around 1900. It aims to clarify lines of influence and controversial issues connected with Ernst Haeckel, particularly in terms of the mutual interconnectedness and influence of intra-academic changes and cultural reflections.

  2. Closing remarks: a series of reflections freely inspired by IWM2003

    International Nuclear Information System (INIS)

    Di Toro, M.

    2003-01-01

    It is a heavy duty to summarize the highlights of such very rich and stimulating workshop. I will take advantage of some guidelines emerged in the intense discussions around the world consensus initiative recently launched inside the community of the heavy ion physics at the Fermi and intermediate energies.It is now well established that in this energy range we observe sharp changes in the reaction mechanisms with direct effects related to the nuclear Equation of State (EOS). We experience however a large dispersion in the data as well as in the theoretical understanding. This contributes to make difficult to clarify the goals of this research field, the main results and the most relevant objectives to pursue in the near future. In this respect the IWM2003 has lead to significant improvements. I will try to present some personal views along this line and under 4 topics: 1) the nuclear liquid-gas phase transition, 2) equation of state, 3) dynamical simulation codes, and 4) outlook. (author)

  3. Important remarks on the problem of neutrino passing through the matter

    International Nuclear Information System (INIS)

    Beshtoev, Kh.M.

    2011-01-01

    It is supposed that resonance enhancement of neutrino oscillations in the matter appears while a neutrino is passing through the matter. It is shown that Wolfenstein equation, for a neutrino passing through the matter, has a disadvantage (it does not take into account the law of momentum conservation; i.e., it is supposed that in the matter the neutrino energy changes, but its momentum does not). It leads, for example, to changing the effective mass of the neutrino by the value 0.87 · 10 -2 eV from a very small value of energy polarization of the matter caused by the neutrino, which is equal 5 · 10 -12 eV. After removing this disadvantage (i.e., taking into account that neutrino momentum also changes in matter) we have obtained a solution to this equation. In this solution a very small enhancement of neutrino oscillations in the solar matter appears due to the smallness of the energy polarization of the matter caused by the neutrino. Two possible solutions to this equation are also given for the limiting cases

  4. Remarks on the necessity and implications of state-dependence in the black hole interior

    CERN Document Server

    Papadodimas, Kyriakos

    2016-01-01

    We revisit the "state-dependence" of the map that we proposed recently between bulk operators in the interior of a large AdS black hole and operators in the boundary CFT. By refining recent versions of the information paradox, we show that this feature is necessary for the CFT to successfully describe local physics behind the horizon --- not only for single-sided black holes but even in the eternal black hole. We show that state-dependence is invisible to an infalling observer who cannot differentiate these operators from those of ordinary quantum effective field theory. Therefore the infalling observer does not observe any violations of quantum mechanics. We successfully resolve a large class of potential ambiguities in our construction. We analyze states where the CFT is entangled with another system and show that the ER=EPR conjecture emerges from our construction in a natural and precise form. We comment on the possible semi-classical origins of state-dependence.

  5. Introductory remarks at the Global Threat Reduction Initiative Partners Conference (GTRI). 18 September 2004, Vienna, Austria

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2004-01-01

    The security of nuclear and other radioactive material has taken on dramatically heightened significance in recent years, due to a number of factors: first, the increasing awareness that nuclear weapons related 'know-how' is no longer confined to a relatively few countries; second, the uncovering of an illicit procurement network capable of supplying nuclear designs and equipment; and third, the rise of extremist groups that have demonstrated an interest in obtaining and using nuclear and radiological weapons. Against this background, the need to protect nuclear material and facilities, and to control nuclear material and radioactive sources, has become an ever more global priority. The IAEA has been active in the field of nuclear security for many years, but the urgency and scope of our efforts underwent a 'sea-change' in the months following September 2001. International cooperation has become the hallmark of these security efforts. While nuclear security is and should remain a national responsibility, many countries still lack the programmes and the resources to respond properly to the threat of nuclear and radiological terrorism. International efforts are focused both on assisting these countries in strengthening their programmes, and on building global networks for combating cross-border threats. The Agency's work has three main points of focus: prevention, detection and response. Our first objective is to assist States in preventing any illicit or non-peaceful use of nuclear or other radioactive materials - including acts of terrorism. This requires effective physical protection of nuclear materials in use, storage and transport, as well as protection of related nuclear facilities. It demands strong State programmes for accounting and control of nuclear material. It recognizes the benefits of the conversion of research reactors to use low enriched uranium a process that requires substantial funding and, in some cases, the development of technological

  6. Avatar' remarks on the carbon input threshold in the sloping croplands

    Science.gov (United States)

    Novara, Agata; Gristina, Luciano; García-Díaz, Andrés; Menghin, Riccardo; Cerdà, Artemi

    2015-04-01

    The erosion processes has been recognized as a major treat to land degradation and to the sustainability of agriculture (Gulati and Rai, 2014; Cerda, 2010). Soil erosion by water causes significant ecological damage; it decreases soil fertility, affecting hydrological properties and soil aggregates stability, nutrients and biological activity and reducing soil carbon. The agricultural land degradation by erosion is, moreover, exacerbated by inappropriate soil management techniques. It is the case of most of Mediterranean vineyards where in addition to environmental factors (high slope, rainfall with high intensity), soil management with continuous tillage and absence of plant cover accelerate erosion process (Novara et al., 2011; Ruiz-Colmenero et al., 2012, Bochet et al., 2010; Ries, 2010; Martín-Moreno et al., 2013). For this reason in the last decades have been developed an alternative soil management such us cover crop under vineyard in order to reduce erosion and improve soil organic carbon level by the increase of carbon input into the soil. The avatar wonder: The loss of Carbon by water under alternative soil management could exceed the total C loss under conventional soil management? Is there a C threshold devised for each terrestrial ecosystem? If C input under alternative management increase, soil will reach a saturation C level? The soil science avatar will show the scenario of a conceptual model applied in a Mediterranean sloping vineyard. Acknowledgements To the "Ministerio de Economía and Competitividad" of Spanish Government for finance the POSTFIRE project (CGL2013- 47862-C2-1-R). The research projects GL2008-02879/BTE, LEDDRA 243857 and PREVENTING AND REMEDIATING DEGRADATION OF SOILS IN EUROPE THROUGH LAND CARE (RECARE)FP7-ENV-2013- supported this research. References Barbera, V., Poma, I., Gristina, L., Novara, A., Egli, M. 2012. Long-term cropping systems and tillage management effects on soil organic carbon stock and steady state level of C

  7. REMARKS ON THE ACCOUNTING TREATMENT OF GOODWILL AT THE LEVEL OF BLOCKS OF TRADING COMPANIES

    Directory of Open Access Journals (Sweden)

    Violeta Isai

    2015-05-01

    Full Text Available This paper presents the accounting treatment of goodwill, namely, its recognition, assessment and accounting, as part of the patrimonial assets of an economic entity. Specific, due to its structure, to any blocks of companies, the goodwill represents the cost surplus of an active block to the market value of the net purchased assets. Why would anyone pay for a company more than its actual accounting worth? Because the extra price is usually attributed to those intangible elements that cannot be assessed separately but whose horizon of expectation is usually related to prospective economic advantages such as the clientele, the top commercial location, the employees' level of training, market shares, good relationships with the employees, the suppliers, the banks etc. Many of the Romanian economic entities were sold at a price that was inferior to their accounting value because, following their assessment, the experts were able to ascertain the following: the existence of fixed assets that needed to be scrapped; the existence of stocks that were either depreciated or difficult to sell; the existence of outstanding debts that were either uncertain of lost for good; the existence of major debts carrying interest. The effect of such assessments led to a reduced marked value of all assets and an increased market value of the debts, or in other words, the possibility of a badwill occurrence. The relationship goodwill – badwill, specific to the blocks of trading companies, represents a current challenge in the recognition and evaluation of the goodwill in compliance with the current Romanian legislation as harmonized with the international accountancy standards.

  8. An osteobiography of a remarkable protohistoric Chamorro man from Taga, Tinian

    Directory of Open Access Journals (Sweden)

    Sawa, V.J.

    2012-12-01

    Full Text Available This work offers skeletal evidence-based interpretations of the life of a 16th–17th century Chamorro man, designated Taotao Tagga', who was buried on the island of Tinian. We focus on osteological changes that illuminate chapters of his life history, and additionally examine these changes in relation to his society and culture. An eventful, arduous, traumatic yet fortunate life is revealed by his physical remains. During the span of the late 17th century Spanish-Chamorro Wars, or perhaps an earlier period of inter-village skirmishing, he suffered a serious penetrating wound to his face, but complete healing of this wound suggests that he benefitted from effective traditional medical interventions, of which we suggest a few. We advance the proposition that work activities, likely initiated at a young age and focusing on megalithic stone processing and building, produced many of the activity-related changes to his skeleton, including the development of posterior cranial superstructures, adaptive remodeling and enthesopathic changes at tendon and ligament attachment sites on his appendicular skeleton, arthritic changes to his joints, and the development of extremely robust long bones, especially those of the upper limb. An index of his humeral robusticity, and related musculo-skeletal strength, is close the upper end of the range of known variation for modern and archaic humans. As Taotao Tagga' was part of a cohort of other Chamorro “strong men,” we examine the quality of life and evolutionary underpinnings of their large body size and great strength. Additionally, we consider how and why Taotao Tagga'’s skeletal changes may bear the signature of a semi-specialist stoneworker and builder, reflecting demographic and socio-political trends during his life, in his home district in Tinian.

  9. The remarkable medical lineage of the Monro family: contributions of Alexander primus, secundus, and tertius.

    Science.gov (United States)

    Wu, Osmond C; Manjila, Sunil; Malakooti, Nima; Cohen, Alan R

    2012-06-01

    Among the families that have influenced the development of modern medicine into what it is today, the Monro lineage stands as one of the most notable. Alexander Monro primus (1697-1767) was the first of 3 generations with the same name, a dynasty that spanned 126 years occupying the Chair of Anatomy one after the other at the University of Edinburgh. After becoming Professor of Anatomy at the University of Edinburgh in 1719, Monro primus played a principal role in the establishment of the University of Edinburgh School of Medicine and the Edinburgh Royal Infirmary. In 1726, he published The Anatomy of the Humane Bones, of which 8 editions were printed during his lifetime. His son, Alexander Monro secundus (1733-1817), arguably the most notable of the 3 men, succeeded him as Professor of Anatomy. A highly regarded lecturer and anatomist, Monro secundus studied under many great physicians, including William Hunter and Johann Friedrich Meckel the Elder, and was also teacher to other well-known figures at the time, such as Joseph Black and Thomas Trotter. His most notable contributions include his work with the lymphatic system, the interventricular foramen (of Monro), and the Monro-Kellie doctrine. Alexander Monro tertius (1773-1859), the last of the dynasty, also succeeded his father as Professor of Anatomy. His work included insights into abdominal aortic aneurysms and the anatomy of the genitourinary system. The prominent association of the Monro family with the University of Edinburgh and the effects of a tenured professorship under the concept of "Ad vitam aut culpam" over successive generations are also described. To the best of the authors' knowledge, this historical review of the Monro family is among the few published in neurosurgical literature. A vivid historical overview of the medical contributions of the most famous and influential dynasty of physicians in Edinburgh at that time is provided, with relevant excerpts from original publications.

  10. Remarks on time-dependent [current]-density functional theory for open quantum systems.

    Science.gov (United States)

    Yuen-Zhou, Joel; Aspuru-Guzik, Alán

    2013-08-14

    Time-dependent [current]-density functional theory for open quantum systems (OQS) has emerged as a formalism that can incorporate dissipative effects in the dynamics of many-body quantum systems. Here, we review and clarify some formal aspects of these theories that have been recently questioned in the literature. In particular, we provide theoretical support for the following conclusions: (1) contrary to what we and others had stated before, within the master equation framework, there is in fact a one-to-one mapping between vector potentials and current densities for fixed initial state, particle-particle interaction, and memory kernel; (2) regardless of the first conclusion, all of our recently suggested Kohn-Sham (KS) schemes to reproduce the current and particle densities of the original OQS, and in particular, the use of a KS closed driven system, remains formally valid; (3) the Lindblad master equation maintains the positivity of the density matrix regardless of the time-dependence of the Hamiltonian or the dissipation operators; (4) within the stochastic Schrödinger equation picture, a one-to-one mapping from stochastic vector potential to stochastic current density for individual trajectories has not been proven so far, except in the case where the vector potential is the same for every member of the ensemble, in which case, it reduces to the Lindblad master equation picture; (5) master equations may violate certain desired properties of the density matrix, such as positivity, but they remain as one of the most useful constructs to study OQS when the environment is not easily incorporated explicitly in the calculation. The conclusions support our previous work as formally rigorous, offer new insights into it, and provide a common ground to discuss related theories.

  11. Self-assembled thin film of imidazolium ionic liquid on a silicon surface: Low friction and remarkable wear-resistivity

    International Nuclear Information System (INIS)

    Gusain, Rashi; Kokufu, Sho; Bakshi, Paramjeet S.; Utsunomiya, Toru; Ichii, Takashi; Sugimura, Hiroyuki; Khatri, Om P.

    2016-01-01

    Graphical abstract: - Highlights: • Ionic liquid thin film is deposited on a silicon surface via covalent interaction. • Chemical and morphological features of ionic liquid thin film are probed by XPS and AFM. • Ionic liquid thin film exhibited low and steady friction along with remarkable wear-resistivity. - Abstract: Imidazolium-hexafluorophosphate (ImPF_6) ionic liquid thin film is prepared on a silicon surface using 3-chloropropyltrimethoxysilane as a bifunctional chemical linker. XPS result revealed the covalent grafting of ImPF_6 thin film on a silicon surface. The atomic force microscopic images demonstrated that the ImPF_6 thin film is composed of nanoscopic pads/clusters with height of 3–7 nm. Microtribological properties in terms of coefficient of friction and wear-resistivity are probed at the mean Hertzian contact pressure of 0.35–0.6 GPa under the rotational sliding contact. The ImPF_6 thin film exhibited low and steady coefficient of friction (μ = 0.11) along with remarkable wear-resistivity to protect the underlying silicon substrate. The low shear strength of ImPF_6 thin film, the covalent interaction between ImPF_6 ionic liquid thin film and underlying silicon substrate, and its regular grafting collectively reduced the friction and improved the anti-wear property. The covalently grafted ionic liquid thin film further shows immense potential to expand the durability and lifetime of M/NEMS based devices with significant reduction of the friction.

  12. Proclus' Elaboration of Platonic Remarks on the Problem of Evils, and their Relation to Divine Providence and Efficiency

    Directory of Open Access Journals (Sweden)

    Reza korrang beheshti

    2014-06-01

    Full Text Available Although there is not a fully developed theory of evil in Plato, some various remarks are interspersed throughout his dialogues which provided the main materials for subsequent Platonists to elaborate a systematic doctrine of evil. Proclus is the most distinguished philosopher of the later Neoplatonism whose view became authoritative within the School and thus is most representative of the Neoplatonic doctrine of evil. By a critical assessment of the antecedent theories of evil, Proclus attempts to give a monistic interpretation of Platonic remarks on the problem of evil. According to his explanation, the higher degrees and principles of Being are only and purely good and are not the causes of evils but the good things for all things alone. Evils, however, exist necessarily but only among particular beings in a relative, parasitic, accidental way and dependent upon the good. The parasitic accidental existence of evil does not have a real efficient cause. It arises due to an asymmetry between the activities of the several faculties or powers of a complex particular being. Moreover, the existence of evil is so mixed with and dependent upon the good that despite its opposition to the good, contributes, in its own manner, to the fulfillment of goodness of the whole Universe, being thus reconcilable with Divine Providence and Efficiency.

  13. Radiometric age determination on some granitic rocks in the Hida Range, central Japan. Remarkable age difference across a fault

    International Nuclear Information System (INIS)

    Ito, Hisatoshi; Tanaka, Kazuhiro

    1999-01-01

    K-Ar and zircon fission-track dating was carried out on some granitic rocks in the Hida Range, central Japan. The samples analyzed were collected on both sides of one of the major faults in the Hida Range: the Kurobe-Takase fracture zone. Ages obtained west of the fault are ∼60 Ma, while those obtained to the east of the fault are less than ∼5 Ma. These results indicate a remarkable age difference across the fault. The Okukurobe granite, located west of the fault, cooled rapidly from ∼600degC to ∼240degC between 60-55 Ma, and the Kanazawa granodiorite, located east of the fault, cooled rapidly from ∼600degC to ∼240degC between 5-1 Ma. The Okukurobe granite has remained cooler than ∼240degC since ∼55 Ma. Thus, it was found that the granitic rocks across the fault have experienced a remarkable different cooling history. (author)

  14. Welcoming remark - International Conference on Nuclear Knowledge Management, 7-10 September 2004, Saclay, France

    International Nuclear Information System (INIS)

    Halm, J. van

    2004-01-01

    Full text: 1. EUSIDIC EUSIDIC, the 'European Association of Information Services', was founded in the 1970s as the 'European Society of Information Dissemination Centres', when the online information industry emerged. EUSIDIC acts as an umbrella association of different groups with a common interest. The different groups represent information users, such as knowledge managers, corporate information managers, university librarians and representatives from the information industry - information producers, providers and aggregators. In addition to the main objectives of EUSIDIC are communication between members and support for effective access to information resources. EUSIDIC differs from most other information associations, because of the nature of its members - users from corporate, government and university libraries as well as information providers. This fact makes EUSIDIC a unique meeting platform. Our members are either information users or information producers, providers or aggregators, as well as software suppliers/facilitators in this area. EUSIDIC acts as an umbrella organisation for different communities of shared practices. These communities or groups, represent corporate and academic users of information, information and content producers, aggregators and distributors. See also our Strategic Plan 2003-2005, which presents and discuss our present and future activities. One of challenges is to serve Meeting opportunities, discussion platform notably for users and providers, information exchange, reviewing information policies and lobbying. Our website (http://www.eusidic.org) is being re-designed and will become an even better tool for demonstrating member benefits, such as: + activities, + conferences, + directory of members, + news and press releases (ready for e-mail distribution), + members news, + monthly member profile (Member of the Month); + special offers to members: discounts, etc.; + member tips: = URLs, publications, other meetings

  15. Remarks at Institute of Retraining and Professional Development, 2 April 2012, Minsk, Belarus

    International Nuclear Information System (INIS)

    Amano, Y.

    2012-01-01

    Full text: Good morning, Ladies and Gentlemen. I am delighted to address participants in this training course for first responders to nuclear and radiological emergencies. Belarus gained considerable experience in responding to nuclear emergencies after the Chernobyl disaster in 1986, which had a significant effect on your country. Experts from Belarus have shared the knowledge and expertise acquired through that experience with the IAEA and its Member States. This proved extremely valuable when we had to respond to another nuclear emergency in my home country a year ago. I am referring, of course, to the Fukushima Daiichi accident. That accident was a reminder to all of us that, when it comes to nuclear safety, we cannot take anything for granted. I visited Fukushima Daiichi several months after the accident and was filled with admiration for the courage and dedication of everyone at the site. Their work to restore normality was undertaken in difficult conditions and at great personal risk. All of us owe a debt of gratitude to the men and women who are willing to undertake the potentially dangerous work of first response after a nuclear or radiological emergency. Your work is vitally important. As you may know, good progress has been made in restoring normality at the Fukushima Daiichi plant. The Japanese authorities have declared that cold shut down status has been achieved. The IAEA has been doing everything it can to help Japan bring the situation at the site under control and to mitigate the consequences of the accident. The IAEA's Incident and Emergency Centre, led by my distinguished Belarussian colleague Dr Elena Buglova, worked around the clock for many months to address this accident. We will continue to assist Japan in tackling the challenging work of decontamination and remediation in the affected areas. Last September, our Member States endorsed a 12-point IAEA Action Plan on Nuclear Safety. I will not list all 12 elements, but they included agreement

  16. TU-EF-207-01: Introductory Remarks on Recent Advances in Breast Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Karellas, A. [University of Massachusetts Medical School (United States)

    2015-06-15

    Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images. Depending on the detector and associated electronics, there are a number of ways this can be accomplished. Spectral mammography using photon-counting detectors can suppress electronic noise and importantly, it enables decomposition of the image into various material compositions of interest facilitating quantitative imaging. Spectral imaging can be particularly important in intravenously injected contrast mammography and eventually tomosynthesis. The various approaches and applications of spectral mammography are discussed. Digital breast tomosynthesis relies on the mechanical movement of the x-ray tube to acquire a number of projections in a predefined arc, typically from 9 to 25 projections over a scan angle of +/−7.5 to 25 degrees depending on the particular system. The mechanical x-ray tube motion requires relatively long acquisition time, typically between 3.7 to 25 seconds depending on the system. Moreover, mechanical scanning may have an effect on the spatial resolution due to internal x-ray filament or external mechanical vibrations. New x-ray source arrays have been developed and they are aimed at replacing the scanned x-ray tube for improved acquisition time and potentially for higher spatial resolution. The potential advantages and challenges of this approach are described. Combination of digital mammography and tomosynthesis in a single system places increased demands on certain functional aspects of the detector and overall performance, particularly in the tomosynthesis

  17. TU-EF-207-01: Introductory Remarks on Recent Advances in Breast Imaging

    International Nuclear Information System (INIS)

    Karellas, A.

    2015-01-01

    Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images. Depending on the detector and associated electronics, there are a number of ways this can be accomplished. Spectral mammography using photon-counting detectors can suppress electronic noise and importantly, it enables decomposition of the image into various material compositions of interest facilitating quantitative imaging. Spectral imaging can be particularly important in intravenously injected contrast mammography and eventually tomosynthesis. The various approaches and applications of spectral mammography are discussed. Digital breast tomosynthesis relies on the mechanical movement of the x-ray tube to acquire a number of projections in a predefined arc, typically from 9 to 25 projections over a scan angle of +/−7.5 to 25 degrees depending on the particular system. The mechanical x-ray tube motion requires relatively long acquisition time, typically between 3.7 to 25 seconds depending on the system. Moreover, mechanical scanning may have an effect on the spatial resolution due to internal x-ray filament or external mechanical vibrations. New x-ray source arrays have been developed and they are aimed at replacing the scanned x-ray tube for improved acquisition time and potentially for higher spatial resolution. The potential advantages and challenges of this approach are described. Combination of digital mammography and tomosynthesis in a single system places increased demands on certain functional aspects of the detector and overall performance, particularly in the tomosynthesis

  18. Remarks on numerical semigroups

    International Nuclear Information System (INIS)

    Torres, F.

    1995-12-01

    We extend results on Weierstrass semigroups at ramified points of double covering of curves to any numerical semigroup whose genus is large enough. As an application we strengthen the properties concerning Weierstrass weights state in [To]. (author). 25 refs

  19. CAPITALIST CRISIS: BRIEF REMARKS

    Directory of Open Access Journals (Sweden)

    José Claudinei Lombardi

    2010-01-01

    Full Text Available Based on the joint context of the theory of crises and the resultant theory of revolutions of Marx and Engels for the analysis of the genesis, development and death of Capitalism, a summary of the historical confronts from which relations of capital have been hegemonic in the XX and XXI centuries is presented. Within this same context, a synthesis of the debates on the structural crisis of Capitalism in the past years is made with an emphasis on its relevance and seriousness in history. It is emphasized that communism is not an idea to be implemented but a reality to be constructed by real men in struggles, conquests and defeats. The revolution of a way of production is not made by itself or by decree, but it is in fact the product of organized men. It is claimed that the maturing of a struggle may lead to the formation of a wide front to articulate anti-capitalist and revolutionary forces. It is observed the need for a tactic and strategic organization to overcome the logics of the Capital and the role each educationalist must play to expand and deepen the debate.

  20. A remarkable legacy

    Science.gov (United States)

    Parkinson, Stuart

    2008-02-01

    Joseph Rotblat, who died in 2005 at the age of 96, was a rare combination of distinguished scientist and leading peace advocate. During the Second World War he was involved with the Manhattan Project - which created the world's first atomic bombs - but then decided to resign on ethical grounds. This life-changing decision set the scene for the dual role that he would play for the rest of his life. On the one hand, Rotblat was a key figure in setting up and leading the Pugwash Conferences on Science and World Affairs, which bring together scientists and public figures concerned with reducing the danger of armed conflict and seeking co-operative solutions for global problems. On the other, he was an accomplished nuclear and medical physicist, eventually becoming president of the British Institute of Radiology.

  1. Concluding Remarks%序

    Institute of Scientific and Technical Information of China (English)

    Sunney I.Chan

    1997-01-01

    @@ Thank you for your kind introduction, T.L. I am, of course, honored to have been the Honorary Chairman of ISOC 4, and I thank the Organizing Committee for bestowing this honoron me. As you know, I am not a card- carrying organic chemist, and one might wonder what a physical biochemist could really contribute to this Symposium. But, as Professor Chi - Huey Wong noted during his keynote address, I am over the hill in my own field. Perhaps, my colleagues at CUHK think I might be able to begin a second career as an organic chemist. Lest you question the seriousness of this suggestion, my students and I have recently published in the Journal of Organic Chemistry and Tetrahedron Letters!

  2. Preliminary y remarks y

    Indian Academy of Sciences (India)

    ranjeetha

    for Women in India brought o ... 2) A Girl's Guide to Life in S ... mathematics or science (man women). We dont seem to have our Larr. B ill d b ... family balance. ... awareness for this not just also the parents, the also the parents, the work.

  3. Mathematics Admission Test Remarks

    Directory of Open Access Journals (Sweden)

    Ideon Erge

    2016-12-01

    Full Text Available Since 2014, there have been admission tests in mathematics for applicants to the Estonian University of Life Sciences for Geodesy, Land Management and Real Estate Planning; Civil Engineering; Hydraulic Engineering and Water Pollution Control; Engineering and Technetronics curricula. According to admission criteria, the test must be taken by students who have not passed the specific mathematics course state exam or when the score was less than 20 points. The admission test may also be taken by those who wish to improve their state exam score. In 2016, there were 126 such applicants of whom 63 took the test. In 2015, the numbers were 129 and 89 and in 2014 150 and 47 accordingly. The test was scored on scale of 100. The arithmetic average of the score was 30.6 points in 2016, 29.03 in 2015 and 18.84 in 2014. The test was considered to be passed with 1 point in 2014 and 20 points in 2015 and 2016. We analyzed test results and gave examples of problems which were solved exceptionally well or not at all.

  4. Remarks on stochastic acceleration

    International Nuclear Information System (INIS)

    Graeff, P.

    1982-12-01

    Stochastic acceleration and turbulent diffusion are strong turbulence problems since no expansion parameter exists. Hence the problem of finding rigorous results is of major interest both for checking approximations and for reference models. Since we have found a way of constructing such models in the turbulent diffusion case the question of the extension to stochastic acceleration now arises. The paper offers some possibilities illustrated by the case of 'stochastic free fall' which may be particularly interesting in the context of linear response theory. (orig.)

  5. Some remarks about decontamination

    International Nuclear Information System (INIS)

    Bertini, A.

    1990-01-01

    Decontamination in itself is not the elimination of a problem, but corresponds to move that problem from one place to another. It is beneficial only if the contamination is less of a nuisance when moved to the ''other place''. Therefore any prospective decontamination process is to be considered essentially in terms of cost-benefit, and in particular in terms of reducing the burden on the waste management systems. The paper is not intended to deal with and to review critically the technical aspects of the various decontamination processes which are currently available. Its aim is to call the attention of those who may be faced with the problem of large-scale decontamination, so that this operation is carried out after all practical aspects have been examined. (author)

  6. Probe Techniques. Introductory Remarks

    Energy Technology Data Exchange (ETDEWEB)

    Emeleus, K. G. [School of Physics and Applied Mathematics, Queen' s University, Belfast (United Kingdom)

    1968-04-15

    In this brief introduction to the session on probes, the history of theii development is first touched on briefly. Reference is then made to the significance of the work to be described by Medicus, for conductivity and recombination calculations, and by Lam and Su, for a wide range of medium and higher pressure plasmas. Finally, a number of other probe topics are mentioned, including multiple probes; probes in electronegative plasmas; resonance probes; probes in noisy discharges; probes as oscillation detectors; use of probes where space-charge is not negligible. (author)

  7. Momentum distributions: opening remarks

    International Nuclear Information System (INIS)

    Weigold, E.

    1982-01-01

    The problem of the hydrogen atom has played a central role in the development of quantum mechanics, beginning with Bohr's daring speculations. It was also the first problem tackled by Schroedinger with his new wave mechanics and similarly it was used by Heisenberg in his first papers as a prime example of the success of quantum mechanics. It has always played a central role in the teaching of quantum physics and has served as a most important heuristic tool, shaping our intuition and inspiring many expositions. The Schroedinger equation for the hydrogen atom is usually solved in the position representation, the solution to the equation being the wave functions psi/sub nlm/(r). If Schroedinger's equation is solved in the momentum representation instead of the coordinate representation, the absolute square of the corresponding momentum state wave function phi/sub nlm/(p) would give the momentum probability distribution of the electron in the state defined by the quantum numbers n, l and m. Three different types of collisions which can take place in the (e,2e) reaction on atomic hydrogen, which is a three body problem, are discussed

  8. Overview and summary remarks

    International Nuclear Information System (INIS)

    Haynes, R.H.

    1990-01-01

    The non-scientific community believes that there is such a thing as safety and that this should be an attainable goal in any technology. People are poor intuitive judges of risks. If the first inducer of mutation to be discovered had been mustard gas rather than ionizing radiation, we probably would not be as concerned about radiation. Radiation is a relatively poor mutagen; it is a good recombinogen but poor compared to ultraviolet and may chemicals for the production of point mutagens. The issue of threshold doses has not been resolved; when one allows for the existence of repair, one opens the possibility that repair-proficient cells could have a dose-response curve with a zero slope at very low doses. Another issue concerns mutagen burden, particularly when comparing radiation with chemicals. Exposure to ionizing radiation may be a very minor component of the total mutagen burden to which we are all exposed. There can exist both synergistic and antagonistic interactions among mutagens. We should not forget the role of metabolism in genetic responses. The responses of cells to mutagens of all kinds are much more complex biochemically than one would imagine on the basis of the simple notion of DNA damage and its error-free or error-prone repair. (L.L.)

  9. Plenary presentations - opening remarks

    Energy Technology Data Exchange (ETDEWEB)

    Simon, R.M.

    1993-12-31

    I am pleased to be here today as one of the U.S. Co-Chairs for the Second U.S./Japan Workshop on Global Change. This series of workshops is an outgrowth of the 1988 bilateral agreement between the U.S. and Japanese governments on scientific and technological cooperation. That agreement called for comparable access to, and exchange of, information in scientific and technological fields, as well as the joint undertaking of cooperative activities for peaceful purposes in nationally important areas of science and technology. Meetings such as this were envisioned under the agreement to allow experts from both sides to discuss and exchange information on scientific and technological aspects of important problems and to identify research and development projects that might usefully be undertaken on a cooperative basis. The first U.S./Japan Workshop on Global Change focused on research needed to better understand how the global climate system operates, what the interactions are between the climate system and marine and terrestrial ecosystems, and how Earth systems might respond to global climatic changes.

  10. Opening keynote remarks

    International Nuclear Information System (INIS)

    Reinwart, W.C.

    1996-01-01

    The outlook for western Canadian natural gas supply was introduced as the principal conference topic, with particular attention to U.S. Midwest markets and the new transportation options from Alberta and British Columbia. Prospects were considered to be excellent, with large connected surplus capacity envisaged well into the next century. Some of the advantages of Canada as a supplier were enumerated: a large resource base, excellent established infrastructure, technical competence, competitive pricing, and political stability

  11. Opening remarks: Preface

    International Nuclear Information System (INIS)

    Beck, Harold L.

    2002-01-01

    This special issue contains the proceedings of the 37th Annual Meeting of the National Council on Radiation Protection and Measurements held 4-5 April 2001 in Arlington, Virginia. The theme of the meeting was 'Fallout from Atmospheric Nuclear Tests-Impact on Science and Society.' Between 1945 and 1980, over 500 nuclear weapons tests were conducted in the atmosphere by the United States, Russia, United Kingdom, France, and China. This practice resulted in the release of large quantities of radioactive materials, which dispersed widely in the atmosphere and deposited on Earth's surface. The measurement of these so-called 'fallout' radionuclides in air, soil, and water and the evaluation of the transfer of these materials to the human body became a significant scientific endeavor. Many national and international monitoring projects were initiated, and extended studies were made of the fallout behavior. An historical overview of the testing and resultant monitoring programs, fallout mechanisms, and estimates of the resultant deposition of fallout is presented in the first paper in this Symposium. University and national laboratory scientists conducted a large number of research programs during the course of weapons tests and fallout. This research resulted in substantial improvements in low-level radioactivity metrology as well as significant advances in the understanding of atmospheric, ecological, and oceanographic processes. Many of these results are still highly pertinent to present-day environmental radiation issues related to the cleanup of contaminated sites, the decommissioning of contaminated facilities, and the assessment of accidents such as occurred at Three Mile Island and at Chernobyl. The results of these investigations were published in thousands of research papers and presented at a number of international conferences held over the processes. The radionuclides served as tracer materials in this regard. The initiation of research on radioactive fallout was the beginning of a new scientific era of opportunity and discovery using the radionuclides injected into the environment from weapons tests as a tool for studying such phenomena as atmospheric chemistry and ecological transfer processes and for developing new methods for the measurement and analysis of low levels of radioactive materials in environmental samples. Webb (1949), of the Eastman Kodak Company of Rochester, New York, was the first to report an occurrence of long-range fallout. He observed 'a new type of radioactive contaminant' in paper packing materials used to separate sensitive photographic films. This observation was made shortly after the first nuclear detonation on 16 July 1945 at Alamogordo, New Mexico, and the two events were immediately linked. During the war years Kodak had encountered radium-contaminated paper, caused by paper and cardboard salvaged and recycled from war plants where radium instrument dials were prepared. The company had therefore instigated a radiation-monitoring program. The paper contaminated by fallout was discovered in August 1945 in paper material that had been produced in Indiana from corn stalks grown in Iowa, some 1,600 km distant from the New Mexico test location. The contamination, identified as 141 Ce, had originated from dust particles deposited from the atmosphere, transferred to river water, and filtered out onto the paper raw material. Even though fallout was detected far from New Mexico as a result of the Trinity test, the systematic monitoring of long-range fallout did not begin until February 1951, 50 y ago. At that time, the testing of nuclear weapons in the atmosphere began in earnest and it was first recognized that fallout formed in the tests could become widely distributed downrange of the test site. Thus, it seemed appropriate for the NCRP at their 2001 annual meeting to mark this 50 y since the initiation of the global fallout monitoring and research programs by providing a forum to look back at the fallout phenomenon and, in particular, at the impact of the resultant investigations on the atmospheric, ecological, oceanographic, and measurement sciences. These scientific achievements are reviewed in the papers in this Symposium volume discussing the 'Impact on Science'

  12. Remarks on entanglement swapping

    International Nuclear Information System (INIS)

    Song, Daegene

    2004-01-01

    In two partially entangled states, entanglement swapping by Bell measurement will yield the weaker entanglement of the two. This scheme is optimal because the average entanglement cannot increase under local operation and classical communication. However, for more than two states, this scheme does not always yield the weakest link. We consider projective measurements other than Bell-type measurement and show, numerically, that while Bell measurement may not be unique, it is indeed optimal among these projective measurements. We also discuss the non-uniqueness of Bell measurements. (letter to the editor)

  13. A remark on accessibility

    International Nuclear Information System (INIS)

    Wu, Xinxing; Wang, Jianjun

    2016-01-01

    Highlights: • Obtain some characteristics of accessibility and Kato’s chaos. • Answer negatively a question in [Li R, Wang H, Zhao Y. Kato’s chaos in duopoly games. Chaos Solit Fract 2016;84:69–72]. • A dynamical system is indecomposable if and only if it is weakly transitive. - Abstract: This note obtains some characteristics of accessibility and Kato’s chaos. Applying these results, an accessible dynamical system whose product system is not accessible is constructed, giving a negative answer to a question in [Li R, Wang H, Zhao Y. Kato’s chaos in duopoly games. Chaos Solit Fract 2016;84:69–72]. Besides, it is proved that every transitive interval self-map is accessible.

  14. Remarks on transparent adverbs

    Directory of Open Access Journals (Sweden)

    Daria Protopopescu

    2007-01-01

    Full Text Available The paper explores the contrast arising between subject/object oriented depictives and manner adverbs. We adopt Geuder’s (2004 label of “transparent” adverbs and embark upon a comparison between this particular class and manner adverbs in English and Romanian, with a look at depictive constructions as well. The problem discussed here is the ambiguity arising in Romanian where most such adverbs seem to overlap their corresponding adjectival forms. Tests will show where they have to be adjoined and the possible readings which they are attached.

  15. Remarks on Batchelor's theorem

    International Nuclear Information System (INIS)

    Blattner, R.J.; Rawnsley, J.H.

    1984-01-01

    The authors show that the structure sheaf of a graded manifold is the sheaf of sections of the exterior algebra bundle of a vector bundle by reducing the problem to one in the theory of extensions of sheaves of commutative algebras to which standard cohomological techniques can be applied. (Auth.)

  16. Welcome and introductory remarks

    International Nuclear Information System (INIS)

    Straalsund, J.L.; Wiley, W.R.; Wagoner, J.D.

    1993-01-01

    Attendees are welcomed to the conference. The general scope of the problem is touched on, and the driving point is made, that the development of new technology is necessary to meet the environmental restoration goals for the Hanford Reservation with a reasonable expenditure of funds and resources. If present technology in treating radioactive waste has to be applied to the wastes prior to final disposal, then the processing costs, and the resultant disposal costs, because of the volume of material to be disposed of, will be tremendous. This conference brings together researchers from national laboratories, universities, and industry to present the scope of the problem, the present status of separation science, and to encourage new technological development

  17. Remarks on energetic biomass

    International Nuclear Information System (INIS)

    Mathis, Paul; Pelletier, Georges

    2011-01-01

    The authors report a study of energy biomass by considering its three main sources (forest, agriculture and wastes) and three energy needs (heat, fuel for transports, electricity) in the French national context. After having recalled the various uses of biomass (animal feeding, energy production, materials, chemical products), the authors discuss the characteristics of biomass with respect to other energy sources. Then, they analyse and discuss the various energy needs which biomass could satisfy: heat production (in industry, in the residential and office building sector), fuel for transports, electricity production. They assess and discuss the possible biomass production of its three main sources: forest, agriculture, and wastes (household, agricultural and industrial wastes). They also discuss the opportunities for biogas production and for second generation bio-fuel production

  18. Remark on Heisenberg's principle

    International Nuclear Information System (INIS)

    Noguez, G.

    1988-01-01

    Application of Heisenberg's principle to inertial frame transformations allows a distinction between three commutative groups of reciprocal transformations along one direction: Galilean transformations, dual transformations, and Lorentz transformations. These are three conjugate groups and for a given direction, the related commutators are all proportional to one single conjugation transformation which compensates for uniform and rectilinear motions. The three transformation groups correspond to three complementary ways of measuring space-time as a whole. Heisenberg's Principle then gets another explanation [fr

  19. Remarkably enhanced gas separation by partial self-conversion of a laminated membrane to metal-organic frameworks.

    Science.gov (United States)

    Liu, Yi; Pan, Jia Hong; Wang, Nanyi; Steinbach, Frank; Liu, Xinlei; Caro, Jürgen

    2015-03-02

    Separation methods based on 2D interlayer galleries are currently gaining widespread attention. The potential of such galleries as high-performance gas-separation membranes is however still rarely explored. Besides, it is well recognized that gas permeance and separation factor are often inversely correlated in membrane-based gas separation. Therefore, breaking this trade-off becomes highly desirable. Here, the gas-separation performance of a 2D laminated membrane was improved by its partial self-conversion to metal-organic frameworks. A ZIF-8-ZnAl-NO3 layered double hydroxide (LDH) composite membrane was thus successfully prepared in one step by partial conversion of the ZnAl-NO3 LDH membrane, ultimately leading to a remarkably enhanced H2 /CH4 separation factor and H2 permeance. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. A remarkable systemic error in calibration methods of γ spectrometer used for determining activity of 238U

    International Nuclear Information System (INIS)

    Su Qiong; Cheng Jianping; Diao Lijun; Li Guiqun

    2006-01-01

    A remarkable systemic error which was unknown in past long time has been indicated. The error appears in the calibration methods of determining activity of 238 U is used with γ-spectrometer with high resolution. When the γ-ray of 92.6 keV as the characteristic radiation from 238 U is used to determine the activity of 238 U in natural environment samples, the disturbing radiation produced by external excitation (or called outer sourcing X-ray radiation) is the main problem. Because the X-ray intensity is changed with many indefinite factors, it is advised that the calibration methods should be put away. As the influence of the systemic errors has been left in some past research papers, the authors suggest that the data from those papers should be cited carefully and if possible the data ought to be re-determined. (authors)

  1. Remarks on the paper ''Two-dimensional quantum field theories involving massless particles'' by N.Nakanishi

    International Nuclear Information System (INIS)

    Stoyanov, D.Ts.

    1978-01-01

    Some critical remarks on the paper by N.Nakanishi ''Tso-Dimensional Quantum Field Theories Involving Massless Particles'' are presented. It is stated that because of the obtained commutation relations the massless scalar fields of the theory connot have the asymptotic behaviour assumed by N.Nakanishi. The contradiction, appearing in the proof of the irreducibility of the scalar field, is demonstrated. Therefore, the theory constructed by Nakanishi, in which an attempt is made to formulate it with the help of one scalar field and correspondingly with one topological charge, is contradictory. It is shown that the statistics of the solutions is not fixed and the solutions satisfying Bose or Fermi statistics differ by constant operator factors

  2. “Are You From The Police, Or What?” Critical Remarks On Ethnographic Fieldwork Among (Disadvantaged) Urban Youth

    DEFF Research Database (Denmark)

    Gravesen, David Thore; Frostholm, Peter Hornbæk

    2016-01-01

    studies. In the fall of 2014 we carried out ethnographic fieldwork (Hastrup 2010, Spradley 1980) in the city of Horsens in Denmark in relation to our research on unstructured socialization among urban youth in urban public spaces. Despite our efforts to explain the young people about our field work......“Are You From The Police, Or What?” Critical Remarks On Ethnographic Fieldwork Among (Disadvantaged) Urban Youth As pointed out by Hammersley and Atkinson (2007) the field observer can experience being perceived as a spy and feeling undeniably unwelcome, especially in the beginning of observation...... and our role as non-SSP (a special Social services, School and Police unit) and non-police, we repeatedly experienced the youngsters questioning our presence. The confusion and skepticism that we experienced emphasized the importance of reflecting our position as researchers (Bourdieu 1999, Goodson...

  3. First remarks on the nesting biology of Hypodynerus andeus (Packard (Hymenoptera, Vespidae, Eumeninae in the Azapa valley, northern Chile

    Directory of Open Access Journals (Sweden)

    Felipe Méndez-Abarca

    2012-06-01

    Full Text Available First remarks on the nesting biology of Hypodynerus andeus (Packard (Hymenoptera, Vespidae, Eumeninae in the Azapa valley, northern Chile. Some aspects about the nesting biology of the potter wasp Hypodynerus andeus (Packard, 1869 are reported for the first time. Observations were carried out at the Azapa valley, coastal desert of northern Chile. A total of sixty nests were collected and examined, each composed by 1-14 cells, most of them found attached to concrete lamp posts. The only preys recorded in the cells were Geometridae (Lepidoptera caterpillars and the presence of the parasitoid Anthrax sp. (Diptera, Bombyliidae was also recorded. A number of arthropods belonging to different groups, mainly spiders, were found occupying empty nests.

  4. Aerobic Oxidation of Benzyl Alcohol on a Strontium-Based Gold Material: Remarkable Intrinsic Basicity and Reusable Catalyst

    Directory of Open Access Journals (Sweden)

    Karla Patrícia R. Castro

    2018-02-01

    Full Text Available The development of stable and active gold catalysts has arisen as a significant strategy for oxidation of alcohols. Nano-size PVA-stabilized gold nanoparticles immobilized on Sr(OH2 by colloidal deposition presented high catalytic activity for benzyl alcohol oxidation. In 2.5 h, 2 bar of O2 and without extra-base addition, the calcined support reached 54.6% (100 °C and 67.4% (140 °C of conversion, presenting the remarkable and unexplored intrinsic basicity that strontium-based materials retain. With sub-stoichiometric K2CO3 adding, under the same catalytic conditions, the catalyst conducted the reaction with similar activity, but with excellent reusability in the process, without any gold leaching. We investigated the influence that the support synthesis method and the solvent used for the NPs stabilization have on the oxidation activity. The produced materials were fully characterized by XPS, Rietveld refinement, and TEM.

  5. Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration

    DEFF Research Database (Denmark)

    Jelnes, Peter; Santoni-Rugiu, Eric; Rasmussen, Morten

    2007-01-01

    The experimental protocols used in the investigation of stem cell-mediated liver regeneration in rodents are characterized by activation of the hepatic stem cell compartment in the canals of Hering followed by transit amplification of oval cells and their subsequent differentiation along hepatic...... the molecular phenotypes of oval cells in several of the most commonly used protocols of stem cell-mediated liver regeneration-namely, treatment with 2-acetylaminofluorene and partial (70%) hepatectomy (AAF/PHx); a choline-deficient, ethionine-supplemented (CDE) diet; a 3,5-diethoxycarbonyl-1,4-dihydro...... remarkable phenotypic discrepancies exhibited by oval cells in stem cell-mediated liver regeneration between rats and mice and underline the importance of careful extrapolation between individual species....

  6. Self-assembled thin film of imidazolium ionic liquid on a silicon surface: Low friction and remarkable wear-resistivity

    Energy Technology Data Exchange (ETDEWEB)

    Gusain, Rashi [CSIR-Indian Institute of Petroleum, Mohkampur, Dehardun 248005 (India); Academy of Scientific and Innovative Research, New Delhi 110025 (India); Kokufu, Sho [Department of Materials Science and Engineering, Kyoto University, Kyoto 606-8501 (Japan); Bakshi, Paramjeet S. [CSIR-Indian Institute of Petroleum, Mohkampur, Dehardun 248005 (India); Utsunomiya, Toru; Ichii, Takashi; Sugimura, Hiroyuki [Department of Materials Science and Engineering, Kyoto University, Kyoto 606-8501 (Japan); Khatri, Om P., E-mail: opkhatri@iip.res.in [CSIR-Indian Institute of Petroleum, Mohkampur, Dehardun 248005 (India); Academy of Scientific and Innovative Research, New Delhi 110025 (India)

    2016-02-28

    Graphical abstract: - Highlights: • Ionic liquid thin film is deposited on a silicon surface via covalent interaction. • Chemical and morphological features of ionic liquid thin film are probed by XPS and AFM. • Ionic liquid thin film exhibited low and steady friction along with remarkable wear-resistivity. - Abstract: Imidazolium-hexafluorophosphate (ImPF{sub 6}) ionic liquid thin film is prepared on a silicon surface using 3-chloropropyltrimethoxysilane as a bifunctional chemical linker. XPS result revealed the covalent grafting of ImPF{sub 6} thin film on a silicon surface. The atomic force microscopic images demonstrated that the ImPF{sub 6} thin film is composed of nanoscopic pads/clusters with height of 3–7 nm. Microtribological properties in terms of coefficient of friction and wear-resistivity are probed at the mean Hertzian contact pressure of 0.35–0.6 GPa under the rotational sliding contact. The ImPF{sub 6} thin film exhibited low and steady coefficient of friction (μ = 0.11) along with remarkable wear-resistivity to protect the underlying silicon substrate. The low shear strength of ImPF{sub 6} thin film, the covalent interaction between ImPF{sub 6} ionic liquid thin film and underlying silicon substrate, and its regular grafting collectively reduced the friction and improved the anti-wear property. The covalently grafted ionic liquid thin film further shows immense potential to expand the durability and lifetime of M/NEMS based devices with significant reduction of the friction.

  7. Transforming the Air National Guard in the 21st Century: How to Balance the Air Guard's "Remarkable Trinity"- The Airman, the Family, and the Employer

    National Research Council Canada - National Science Library

    Comtois, Paul

    2004-01-01

    In his book On War-published in 1852 the great Prussian theorist Carl Von Clausewitz described what we have come to know today as a remarkable trinity that consisted of the government the military and the people...

  8. Remarkable enhancement on elimination reaction of side groups in excimer laser ablation of mixture targets of perylene derivatives with metal powder

    International Nuclear Information System (INIS)

    Nishio, Satoru; Tamura, Kazuyuki; Tsujine, Yukari; Fukao, Tomoko; Nakano, Masayoshi; Matsuzaki, Akiyoshi; Sato, Hiroyasu

    2002-01-01

    Films are deposited on substrates at 20 deg.C by excimer laser ablation (ELA) of mixture targets of 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) with metal powder, PTCDA/M (M=Co, Ni, Fe, W, Cu and Ag) using XeCl and ArF beams. Large amount of fragments with ''naked'' perylene skeletons can be produced owing to effective elimination of carboxylic dianhydride groups by ELA of PTCDA/Co both with XeCl and ArF beams under optimized ablation conditions. Elimination reaction of side groups of PTCDA is observed for ELA of the targets with metal powder of the iron group, Co, Fe and Ni, especially remarkable for Co and Fe. The film from PTCDA/Ni consists of small particles with the various diameters ranging from 10 to 100 nm as well as that from PTCDA/Co. Morphology like petal of rose can be seen everywhere for the film from PTCDA/Fe

  9. An astrophysical interpretation of the remarkable g-mode frequency groups of the rapidly rotating γ Dor star, KIC 5608334

    Science.gov (United States)

    Saio, Hideyuki; Bedding, Timothy R.; Kurtz, Donald W.; Murphy, Simon J.; Antoci, Victoria; Shibahashi, Hiromoto; Li, Gang; Takata, Masao

    2018-06-01

    The Fourier spectrum of the γ-Dor variable KIC 5608334 shows remarkable frequency groups at ˜3, ˜6, ˜9, and 11-12 d-1. We explain the four frequency groups as prograde sectoral g modes in a rapidly rotating star. Frequencies of intermediate-to-high radial order prograde sectoral g modes in a rapidly rotating star are proportional to |m| (i.e. ν ∝ |m|) in the corotating frame as well as in the inertial frame. This property is consistent with the frequency groups of KIC 5608334 as well as the period versus period-spacing relation present within each frequency group, if we assume a rotation frequency of 2.2 d-1, and that each frequency group consists of prograde sectoral g modes of |m| = 1, 2, 3, and 4, respectively. In addition, these modes naturally satisfy near-resonance conditions νi ≈ νj + νk with mi = mj + mk. We even find exact resonance frequency conditions (within the precise measurement uncertainties) in many cases, which correspond to combination frequencies.

  10. A remarkable adsorbent for removal of contaminants of emerging concern from water: Porous carbon derived from metal azolate framework-6.

    Science.gov (United States)

    Bhadra, Biswa Nath; Jhung, Sung Hwa

    2017-10-15

    A series of metal-azolate frameworks or MAFs-MAF-4, -5, and -6-were synthesized and pyrolyzed to prepare porous carbons derived from MAFs (CDM-4, -5, -6, respectively). Not only the obtained carbons but also MAFs were characterized and applied for the adsorption of organic contaminants of emerging concern (CECs, including pharmaceuticals and personal care products) such as salicylic acid, clofibric acid, diclofenac sodium, bisphenol-A, and oxybenzone (OXB) from water. CDM-6 was found to be the most remarkable adsorbent among the tested ones (including activated carbon) for all the adsorbates. OXB was taken as a representative adsorbate for detailed adsorption studies as well as understanding the adsorption mechanism. H-bonding (H-acceptor: CDM; H-donor: CECs) was suggested as the principal mechanism for the adsorption of tested adsorbates. Finally, CDMs, especially CDM-6, were suggested as highly efficient and easily recyclable adsorbents for water purification. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Multifunctional biosynthesized silver nanoparticles exhibiting excellent antimicrobial potential against multi-drug resistant microbes along with remarkable anticancerous properties.

    Science.gov (United States)

    Jha, Diksha; Thiruveedula, Prasanna Kumar; Pathak, Rajiv; Kumar, Bipul; Gautam, Hemant K; Agnihotri, Shrish; Sharma, Ashwani Kumar; Kumar, Pradeep

    2017-11-01

    This study demonstrates the therapeutic potential of silver nanoparticles (AgNPs), which were biosynthesized using the extracts of Citrus maxima plant. Characterization through UV-Vis spectrophotometry, Dynamic Light Scattering (DLS), Fourier Transform Infrared spectroscopy (FTIR), X-ray Diffraction (XRD) and Transmission Electron Microscopy (TEM) confirmed the formation of AgNps in nano-size range. These nanoparticles exhibited enhanced antioxidative activity and showed commendable antimicrobial activity against wide range of microbes including multi-drug resistant bacteria that were later confirmed by TEM. These particles exhibited minimal toxicity when cytotoxicity study was performed on normal human lung fibroblast cell line as well as human red blood cells. It was quite noteworthy that these particles showed remarkable cytotoxicity on human fibrosarcoma and mouse melanoma cell line (B16-F10). Additionally, the apoptotic topographies of B16-F10 cells treated with AgNps were confirmed by using acridine orange and ethidium bromide dual dye staining, caspase-3 assay, DNA fragmentation assay followed by cell cycle analysis using fluorescence-activated cell sorting. Taken together, these results advocate promising potential of the biosynthesized AgNps for their use in therapeutic applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. A brief history of the most remarkable numbers e, i and γ in mathematical sciences with applications

    Science.gov (United States)

    Debnath, Lokenath

    2015-08-01

    This paper deals with a brief history of the most remarkable Euler numbers e, i and γ in mathematical sciences. Included are many properties of the constants e, i and γ and their applications in algebra, geometry, physics, chemistry, ecology, business and industry. Special attention is given to the growth and decay phenomena in many real-world problems including stability and instability of their solutions. Some specific and modern applications of logarithms, complex numbers and complex exponential functions to electrical circuits and mechanical systems are presented with examples. Included are the use of complex numbers and complex functions in the description and analysis of chaos and fractals with the aid of modern computer technology. In addition, the phasor method is described with examples of applications in engineering science. The major focus of this paper is to provide basic information through historical approach to mathematics teaching and learning of the fundamental knowledge and skills required for students and teachers at all levels so that they can understand the concepts of mathematics, and mathematics education in science and technology.

  13. Remarkable photo-catalytic degradation of malachite green by nickel doped bismuth selenide under visible light irradiation

    International Nuclear Information System (INIS)

    Kulsi, Chiranjit; Ghosh, Amrita; Mondal, Anup; Kargupta, Kajari; Ganguly, Saibal; Banerjee, Dipali

    2017-01-01

    Highlights: • Bi_2Se_3 and Ni doped Bi_2Se_3 were synthesized by solvothermal approach. • Presence of nickel was confirmed by X-ray photoelectron spectroscopy (XPS) measurement. • Complete degradation of malachite green (MG) dye was achieved by Ni doped Bi_2Se_3 with H_2O_2. • Remarkable photo-catalytic degradation by doped bismuth selenide has been explained. • Scavenger tests show degradation of MG is mainly dominated by ·OH oxidation process. - Abstract: Bismuth selenide (Bi_2Se_3) and nickel (Ni) doped Bi_2Se_3 were prepared by a solvothermal approach to explore the photo-catalytic performance of the materials in degradation of malachite green (MG). The presence of nickel was confirmed by X-ray photoelectron spectroscopy (XPS) measurement in doped Bi_2Se_3. The results showed that the nickel doping played an important role in microstructure and photo-catalytic activity of the samples. Nickel doped Bi_2Se_3 sample exhibited higher photo-catalytic activity than that of the pure Bi_2Se_3 sample under visible-light irradiation. The photo-catalytic degradation followed first-order reaction kinetics. Fast degradation kinetics and complete (100% in 5 min of visible light irradiation) removal of MG was achieved by nickel doped Bi_2Se_3 in presence of hydrogen peroxide (H_2O_2) due to modification of band gap energies leading to suppression of photo-generated electron-hole recombination.

  14. A remarkable finding that suggests the existence of a new groundwater biome based on chemoautotrophic resources, named

    Directory of Open Access Journals (Sweden)

    Ştefan Negrea

    2009-01-01

    Full Text Available An important work of subterranean biology, signed by Francis Dov Por, Ophel: a groundwater biome based on chemoautotrophic resources. The global significance of the Ayyalon cave finds, Israel is presented and discussed in the present paper. The subject is a remarkable discovery suggesting the existence of a new aquatic subterranean biome autonomous energy based the author calls Ophel, the Hebrew word for “darkness” and “netherworld”. For F.D. Por, this biome links different marine chemosynthetic ecosystems in a global biospheric entity. Finally, F.D. POR hypothesizes on the existence of three overlapped biospheres: the bacteriosphere in the depths of the planet’s crust, which does not require light or oxygen; the aphotic, subterranean deuterobiosphere, formed of bacterial chemosynthesis based eukaryotes and limited-supplied dissolved oxygen from above-ground; the above-ground eubiosphere, based on aerobic photosynthesis. I would like to emphasize that, at my suggestion, Prof. Dr. F.D. Por participated at the 18th International Symposium of Biospeleology from Cluj-Napoca (Romania at 10th to 15th July 2006 where he mentioned for the first time orally some data on the Ayyalon Cave and the Ophel biome.

  15. Psicopatologia, exotismo e diversidade: ensaio de antropologia da psicopatologia Psychopathology, exoticism and diversity: some remarks on the anthropology of psychopathology

    Directory of Open Access Journals (Sweden)

    Adriano Holanda

    2001-12-01

    Full Text Available O texto se propõe a uma reflexão em torno de uma perspectiva antropológica da questão da psicopatologia. Partindo da análise antropológica de Tzvetan Todorov, perpassa o ensaio histórico de Theodore Zeldin, alcançando a crítica de Thomas Szasz e a abordagem histórico-antropológica de Michel Foucault, na tentativa de clarear a compreensão do fenômeno psicopatológico. Nesta perspectiva crítico-histórica, a psicopatologia é vista como um fenômeno contextualizado, inserido na construção das mentalidades específicas da cultura ocidental.The purpose of this paper is to reflect upon an anthropological approach of psychopathology. It intends to throw some light upon the phenomenon of the "psychopathologic". It begins with some remarks on the anthropological concept of Tzevan Todorov. It also analyses Theodore Zeldin’s historical essay, Thomas Szasz’s critical reflections and Michel Foucault’s historic-anthropological approach. In this historical perspective, "Psychopathology" is conceived as a rather contextualized phenomenon, part of the specific mentalities constructed by the Western culture.

  16. A novel α-galactosidase from the thermophilic probiotic Bacillus coagulans with remarkable protease-resistance and high hydrolytic activity

    Science.gov (United States)

    Zhao, Ruili; Zhao, Rui; Tu, Yishuai; Zhang, Xiaoming; Deng, Liping

    2018-01-01

    A novel α-galactosidase of glycoside hydrolase family 36 was cloned from Bacillus coagulans, overexpressed in Escherichia coli, and characterized. The purified enzyme Aga-BC7050 was 85 kDa according to SDS-PAGE and 168 kDa according to gel filtration, indicating that its native structure is a dimer. With p-nitrophenyl-α-d- galactopyranoside (pNPGal) as the substrate, optimal temperature and pH were 55 °C and 6.0, respectively. At 60 °C for 30 min, it retained > 50% of its activity. It was stable at pH 5.0–10.0, and showed remarkable resistance to proteinase K, subtilisin A, α-chymotrypsin, and trypsin. Its activity was not inhibited by glucose, sucrose, xylose, or fructose, but was slightly inhibited at galactose concentrations up to 100 mM. Aga-BC7050 was highly active toward pNPGal, melibiose, raffinose, and stachyose. It completely hydrolyzed melibiose, raffinose, and stachyose in < 30 min. These characteristics suggest that Aga-BC7050 could be used in feed and food industries and sugar processing. PMID:29738566

  17. A novel α-galactosidase from the thermophilic probiotic Bacillus coagulans with remarkable protease-resistance and high hydrolytic activity.

    Directory of Open Access Journals (Sweden)

    Ruili Zhao

    Full Text Available A novel α-galactosidase of glycoside hydrolase family 36 was cloned from Bacillus coagulans, overexpressed in Escherichia coli, and characterized. The purified enzyme Aga-BC7050 was 85 kDa according to SDS-PAGE and 168 kDa according to gel filtration, indicating that its native structure is a dimer. With p-nitrophenyl-α-d- galactopyranoside (pNPGal as the substrate, optimal temperature and pH were 55 °C and 6.0, respectively. At 60 °C for 30 min, it retained > 50% of its activity. It was stable at pH 5.0-10.0, and showed remarkable resistance to proteinase K, subtilisin A, α-chymotrypsin, and trypsin. Its activity was not inhibited by glucose, sucrose, xylose, or fructose, but was slightly inhibited at galactose concentrations up to 100 mM. Aga-BC7050 was highly active toward pNPGal, melibiose, raffinose, and stachyose. It completely hydrolyzed melibiose, raffinose, and stachyose in < 30 min. These characteristics suggest that Aga-BC7050 could be used in feed and food industries and sugar processing.

  18. Terahertz Conductivity within Colloidal CsPbBr3 Perovskite Nanocrystals: Remarkably High Carrier Mobilities and Large Diffusion Lengths.

    Science.gov (United States)

    Yettapu, Gurivi Reddy; Talukdar, Debnath; Sarkar, Sohini; Swarnkar, Abhishek; Nag, Angshuman; Ghosh, Prasenjit; Mandal, Pankaj

    2016-08-10

    Colloidal CsPbBr3 perovskite nanocrystals (NCs) have emerged as an excellent light emitting material in last one year. Using time domain and time-resolved THz spectroscopy and density functional theory based calculations, we establish 3-fold free carrier recombination mechanism, namely, nonradiative Auger, bimolecular electron-hole recombination, and inefficient trap-assisted recombination in 11 nm sized colloidal CsPbBr3 NCs. Our results confirm a negligible influence of surface defects in trapping charge carriers, which in turn results into desirable intrinsic transport properties, from the perspective of device applications, such as remarkably high carrier mobility (∼4500 cm(2) V(-1) s(-1)), large diffusion length (>9.2 μm), and high luminescence quantum yield (80%). Despite being solution processed and possessing a large surface to volume ratio, this combination of high carrier mobility and diffusion length, along with nearly ideal photoluminescence quantum yield, is unique compared to any other colloidal quantum dot system.

  19. Protonated MIL-125-NH2: Remarkable Adsorbent for the Removal of Quinoline and Indole from Liquid Fuel.

    Science.gov (United States)

    Ahmed, Imteaz; Khan, Nazmul Abedin; Yoon, Ji Woong; Chang, Jong-San; Jhung, Sung Hwa

    2017-06-21

    The removal of nitrogen-containing compounds (NCCs) from fossil fuels prior to combustion is currently of particular importance, and so we investigated an adsorptive method using metal-organic frameworks (MOFs) for the removal of indole (IND) and quinoline (QUI), which are two of the main NCCs present in fossil fuels. We herein employed an amino (-NH 2 )-functionalized MIL-125 (MIL-125-NH 2 ) MOF, which was further modified by protonation (P-MIL-125-NH 2 ). These modified MOFs exhibited extraordinary performance in the adsorption of both IND (as representative neutral NCC) and QUI (as representative basic NCC). These MOFs were one of the most efficient adsorbents for the removal of NCCs. For example, P-MIL-125-NH 2 showed the highest adsorption capacity for QUI among ever reported adsorbent. The improved adsorption of IND was explained by H-bonding and cation-π interactions for MIL-125-NH 2 and P-MIL-125-NH 2 , respectively, while the mechanisms for QUI were H-bonding and acid-base interactions, respectively. This is a rare phenomenon for a single material (especially not with very high porosity) to exhibit such remarkable performances in the adsorption of both basic QUI and neutral IND. The adsorption results obtained using regenerated MIL-125-NH 2 and P-MIL-125-NH 2 also showed that these materials can be used several times without any severe degradation.

  20. The impact of event vividness, event severity, and prior paranormal belief on attributions towards a depicted remarkable coincidence experience: Two studies examining the misattribution hypothesis.

    Science.gov (United States)

    Rogers, Paul; Qualter, Pamela; Wood, Dave

    2016-11-01

    Two studies examine the impact event vividness, event severity, and prior paranormal belief has on causal attributions for a depicted remarkable coincidence experience. In Study 1, respondents (n = 179) read a hypothetical vignette in which a fictional character accurately predicts a plane crash 1 day before it occurs. The crash was described in either vivid or pallid terms with the final outcome being either severe (fatal) or non-severe (non-fatal). Respondents completed 29 causal attribution items, one attribution confidence item, nine scenario perception items, a popular paranormal belief scale, and a standard demographics questionnaire. Principal axis factoring reduced the 29 attribution items to four attribution factors which were then subjected to a 2 (event vividness) × 2 (event severity) × 2 (paranormal belief) MANCOVA controlling for respondent gender. As expected, paranormal believers attributed the accurate crash prediction less to coincidence and more to both paranormal and transcendental knowing than did paranormal sceptics. Furthermore, paranormal (psychokinesis) believers deemed the prediction more reflective of paranormal knowing to both (1) a vivid/non-fatal and (2) a pallid/fatal crash depiction. Vividness, severity, and paranormal belief types had no impact on attribution confidence. In Study 2, respondents (also n = 179) generated data that were a moderately good fit to the previous factor structure and replicated several differences across attributional pairings albeit for paranormal non-believers only. Corresponding effects for event severity and paranormal belief were not replicated. Findings are discussed in terms of their support for the paranormal misattribution hypothesis and the impact of availability biases in the form of both vividness and severity effects. Methodological issues and future research ideas are also discussed. © 2016 The British Psychological Society.

  1. All-nanoparticle self-assembly ZnO/TiO₂ heterojunction thin films with remarkably enhanced photoelectrochemical activity.

    Science.gov (United States)

    Yuan, Sujun; Mu, Jiuke; Mao, Ruiyi; Li, Yaogang; Zhang, Qinghong; Wang, Hongzhi

    2014-04-23

    The multilaminated ZnO/TiO2 heterojunction films were successfully deposited on conductive substrates including fluorine-doped tin oxide (FTO) glass and flexible indium tin oxide coated poly(ethylene terephthalate) via the layer-by-layer (LBL) self assembly method from the oxide colloids without using any polyelectrolytes. The positively charged ZnO nanoparticles and the negatively charged TiO2 nanoparticles were directly used as the components in the consecutive deposition process to prepare the heterojunction thin films by varying the thicknesses. Moreover, the crystal growth of both oxides could be efficiently inhibited by the good connection between ZnO and TiO2 nanoparticles even after calcination at 500 °C, especially for ZnO which was able to keep the crystallite size under 25 nm. The as-prepared films were used as the working electrodes in the three-electrode photoelectrochemical cells. Because the well-contacted nanoscale heterojunctions were formed during the LBL self-assembling process, the ZnO/TiO2 all-nanoparticle films deposited on both substrates showed remarkably enhanced photoelectrochemical properties compared to that of the well-established TiO2 LBL thin films with similar thicknesses. The photocurrent response collected from the ZnO/TiO2 electrode on the FTO glass substrate was about five times higher than that collected from the TiO2 electrode. Owing to the absence of the insulating layer of dried polyelectrolytes, the ZnO/TiO2 all-nanoparticle heterojunction films were expected to be used in the photoelectrochemical device before calcination.

  2. Remarkable efficiency of phosphate removal: Ferrate(VI)-induced in situ sorption on core-shell nanoparticles.

    Science.gov (United States)

    Kralchevska, Radina P; Prucek, Robert; Kolařík, Jan; Tuček, Jiří; Machala, Libor; Filip, Jan; Sharma, Virender K; Zbořil, Radek

    2016-10-15

    Despite the importance of phosphorus as a nutrient for humans and its role in ecological sustainability, its high abundance, resulting in large part from human activities, causes eutrophication that negatively affects the environment and public health. Here, we present the use of ferrate(VI) as an alternative agent for removing phosphorus from aqueous media. We address the mechanism of phosphate removal as a function of the Fe/P mass ratio and the pH value of the solution. The isoelectric point of γ-Fe2O3 nanoparticles, formed as dominant Fe(VI) decomposition products, was identified to play a crucial role in predicting their efficiency in removing of phosphates. Importantly, it was found that the removal efficiency dramatically changes if Fe(VI) is added before (ex-situ conditions) or after (in-situ conditions) the introduction of phosphates into water. Removal under in-situ conditions showed remarkable sorption capacity of 143.4 mg P per gram of ferric precipitates due to better accessibility of active surface sites on in-situ formed ferric oxides/oxyhydroxides. At pH = 6.0-7.0, complete removal of phosphates was observed at a relatively low Fe/P mass ratio (5:1). The results show that phosphates are removed from water solely by sorption on the surface of γ-Fe2O3/γ-FeOOH core/shell nanoparticles. The advantages of Fe(VI) utilization include its environmentally friendly nature, the possibility of easy separation of the final product from water by a magnetic field or by natural settling, and the capacity for successful phosphate elimination at pH values near the neutral range and at low Fe/P mass ratios. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Reactor and /or accelerator: general remarks on strategic considerations in sourcing/producing radiopharmaceuticals and radiotracer for the Philippines

    International Nuclear Information System (INIS)

    Nazarea, A.D.

    1996-01-01

    The most important sources of radionuclides in the world are particle accelerators and nuclear reactors. Since the late 1940's many radiotracers and radiopharmaceuticals have been innovated and conceived, designed, produced and applied in important industrial and clinical/ biomedical settings. For example in the health area, reactor-produced radionuclides have become indispensable for diagnostic imaging involving, in its most recent and advanced development, radioimmunoscintigraphy, which exploits the exquisite ligand-specificity of monoclonal antibodies, reagents which in turn are the products of advances in biotechnology. Thus far, one of the most indispensable radiopharmaceuticals has been 99m Tc, which is usually obtained as a daughter decay product of 99 Mo. In January 1991, some questions about the stability of the worldwide commercial supply of 99 Mo became highlighted when the major commercial world producer of 99 Mo, Nordion International, shut down its facilities temporarily in Canada due to contamination in its main reactor building (see for instance relevant newsbrief in J. Nuclear Medicine (1991): 'Industry agrees to join DOE study of domestic moly-99 production'). With the above background, my remarks will attempt to open discussions on strategic considerations relevant to questions of 'self reliance' in radiotracers/radiopharmaceutical production in the Philippines. For instance, the relevant question of sourcing local radionuclide needs from a fully functioning multipurpose cyclotron facility within the country that will then supply the needs of the local industrial, biomedical (including research) and health sectors; and possibly, eventually acquiring the capability to export to nearby countries longer-lived radiotracers and radiopharmaceuticals

  4. Remarkable Diversity of Escherichia coli Carrying mcr-1 from Hospital Sewage with the Identification of Two New mcr-1 Variants

    Directory of Open Access Journals (Sweden)

    Feifei Zhao

    2017-10-01

    Full Text Available The plasmid-borne colistin-resistant gene mcr-1 has rapidly become a worldwide public health concern. This study aims to determine the host bacterial strains, plasmids, and genetic contexts of mcr-1 in hospital sewage. A 1-ml hospital sewage sample was cultured. Colistin-resistant bacterial colonies were selected on agar plates and were subjected to whole genome sequencing and subsequent analysis. The transfer of mcr-1 between bacterial strains was tested using conjugation. New variants of mcr-1 were cloned to test the impact of variations on the function of mcr-1. Plasmids carrying mcr-1 were retrieved from GenBank for comparison based on concatenated backbone genes. In the sewage sample, we observed that mcr-1 was located in various genetic contexts on the chromosome, or plasmids of four different replicon types (IncHI2, IncI2, IncP, and IncX4, in Klebsiella pneumoniae, Kluyvera spp. and seven Escherichia coli strains of six different sequence types (ST10, ST34, ST48, ST1196, ST7086, and ST7087. We also identified two new variants of mcr-1, mcr-1.4 and mcr-1.7, both of which encode an amino acid variation from mcr-1. mcr-1-carrying IncX4 plasmids, which have a global distribution across the Enterobacteriaceae, are the result of global dissemination of a single common plasmid, while IncI2 mcr-1 plasmids appear to acquire mcr-1 in multiple events. In conclusion, the unprecedented remarkable diversity of species, strains, plasmids, and genetic contexts carrying mcr-1 present in a single sewage sample from a single healthcare site highlights the continued evolution and dynamic transmission of mcr-1 in healthcare-associated environments.

  5. Electrochemical synthesis of multi-armed CuO nanoparticles and their remarkable bactericidal potential against waterborne bacteria

    Energy Technology Data Exchange (ETDEWEB)

    Pandey, Pratibha, E-mail: rkpratibha@yahoo.com; Merwyn, S.; Agarwal, G. S.; Tripathi, B. K.; Pant, S. C. [Defence Research and Development Establishment (India)

    2012-01-15

    Copper (II) oxide multi-armed nanoparticles composed of 500-1000 nm long radiating nanospicules with 100-200 nm width near the base and 50-100 nm width at the tapered ends and {approx}25 nm thickness were synthesized by electrochemical deposition in the presence of an oxidant followed by calcination at 150 Degree-Sign C. The nanoparticles were characterized using SEM/EDX for morphology and composition, Raman spectroscopy for compound identification, and broth culture method for antibacterial efficacy. The CuO nanoparticles have shown remarkable bactericidal efficacy against Gram-positive and -negative waterborne disease causing bacteria like Escherichia coli, Salmonella typhi, staphylococcus aureus and Bacillus subtilis. E. coli has been chosen as representative species for waterborne disease causing bacteria. In antibacterial tests 500 {mu}g/mL nano CuO killed 3 Multiplication-Sign 10{sup 8} CFU/mL E. coli bacteria within 4 h of exposure. Moreover, 8.3 Multiplication-Sign 10{sup 6} CFU/mL E. coli were killed by 100 and 10 {mu}g/mL nano CuO within 15 min and 4 h of exposure, respectively. Antibacterial activity of nano CuO has been found many-fold compared with commercial bulk CuO. The fate of nanoparticles after antibacterial test has also been studied. The synthesized CuO nanoparticles are expected to have potential antibacterial applications in water purification and in paints and coatings used on frequently touched surfaces and fabrics in hospital settings.

  6. Remarkably enhanced photoluminescence of hexagonal GdPO4·nH2O:Eu with decreasing size

    International Nuclear Information System (INIS)

    Lu Shaozhe; Zhang Jiahua; Zhang Jishen; Zhao Haifeng; Luo Yongshi; Ren Xinguang

    2010-01-01

    The hexagonal rhabdophane-type GdPO 4 hydrate (GdPO 4 ·nH 2 O) was synthesized via a simple hydrothermal process. The size and morphology of the products can be tunable by adjusting the pH of reaction systems through the addition of aqueous NaOH. The nanorods with a width of 50-100 nm and a length of about 1 μm were obtained in the absence of NaOH (pH = 2), while a significant reduction of size (width: ∼ 10 nm, length: ∼ 50 nm) was observed for the product synthesized in the presence of NaOH (pH = 10). Surprisingly, the small-sized product exhibits a remarkably enhanced photoluminescence quantum yield and long excited state lifetime in comparison with those of the large-sized product. This abnormal luminescence phenomenon is discussed and explained. The EDS and XPS measurements revealed the presence of Na + in the small-sized samples. These Na + cations were probably bonded to the surface O 2- dangling bonds, which thus reduces the number of surface defects that usually serve as the nonradiative energy transfer center channels. A considerable reduction of surface defect centers results in the increase of the emission efficiency and excited state lifetime in a small-sized sample. Obviously, the controlled synthesis of rare-earth-doped nanoparticles with a small size, but with relatively strong luminescence, is significant for their applications in the areas of technologies including optoelectronics, sensing and bioimaging.

  7. Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015.

    Science.gov (United States)

    Yasuda, Mitsuru; Ito, Shin; Hatazaki, Kyoko; Deguchi, Takashi

    2016-12-01

    The antimicrobial resistance of Neisseria gonorrhoeae is a serious problem worldwide. In this study, we examined the susceptibility of N. gonorrhoeae isolated from male gonococcal urethritis in Sendai in 2014 and 2015. Furthermore, of all cases, we investigated the clinical efficacy of a single 2-g dose of extended-release azithromycin (AZM-SR) in the treatment of male gonococcal urethritis retrospectively. Sixty N. gonorrhoeae strains in 2014 and 54 strains in 2015 were isolated from male gonococcal urethritis and stored each year. The MIC of AZM was ≥1 mg/L in 4 strains (6.7%) in 2014 and in 13 strains (24.1%) in 2015 and the number of strains having ≥1 mg/L MIC increased significantly (P = 0.016). Microbiological efficacy was evaluated in 32 and 29 of these patients, and the rates of treatment success were 93.8% and 79.3%, respectively. All of the treatment failures were caused by strains having a MIC of AZM of ≥0.5 mg/L. In particular, the increase in the isolates having a MIC of AZM of ≥1 mg/L was remarkable. Therefore, it was thought that the increase in these strains was the reason for the increase in treatment failures in 2015. Because no other drug is effective, it is currently necessary to use AZM-SR to treat gonococcal infections caused by ceftriaxone-resistant strains or patients allergic to ceftriaxone. To prevent a further increase in resistance to AZM, we should not use AZM-SR to treat normal cases of gonococcal infection. Copyright © 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  8. Remarks to Dr. Paul E. Tomaszewski’s comments on the research of Jan Czochralski’s curriculum vitae (a reply (in Polish

    Directory of Open Access Journals (Sweden)

    Michał KOKOWSKI

    2015-12-01

    Full Text Available The author replies to the text entitled “Remarks to the comment by Prof.  Michal Kokowski on the research of Jan Czochralski’s biography” by Dr. Paweł E. Tomaszewski (2015, highlighting the key contentious issues, including the need to rely systematically on historical sources and the criticism thereof.

  9. Peaceful uses of nuclear energy in the 21st century. Opening remarks at the regional public information seminar, Bangkok, 1 February 2000

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2000-01-01

    In his opening remarks at the Regional Public Information Seminar (Bangkok, 1 February 2000), the Director General of the IAEA presented the aim of the seminar as a means to enhance understanding of the peaceful uses of nuclear energy, and the main thrusts of the IAEA's current activities

  10. Geography shapes the phylogeny of frailejones (Espeletiinae Cuatrec., Asteraceae: a remarkable example of recent rapid radiation in sky islands

    Directory of Open Access Journals (Sweden)

    Mauricio Diazgranados

    2017-02-01

    Full Text Available Background The páramo ecosystem, located above the timberline in the tropical Andes, has been the setting for some of the most dramatic plant radiations, and it is one of the world’s fastest evolving and most diverse high-altitude ecosystems. Today 144+ species of frailejones (subtribe Espeletiinae Cuatrec., Asteraceae dominate the páramo. Frailejones have intrigued naturalists and botanists, not just for their appealing beauty and impressive morphological diversity, but also for their remarkable adaptations to the extremely harsh environmental conditions of the páramo. Previous attempts to reconstruct the evolutionary history of this group failed to resolve relationships among genera and species, and there is no agreement regarding the classification of the group. Thus, our goal was to reconstruct the phylogeny of the frailejones and to test the influence of the geography on it as a first step to understanding the patterns of radiation of these plants. Methods Field expeditions in 70 páramos of Colombia and Venezuela resulted in 555 collected samples from 110 species. Additional material was obtained from herbarium specimens. Sequence data included nrDNA (ITS and ETS and cpDNA (rpl16, for an aligned total of 2,954 bp. Fragment analysis was performed with AFLP data using 28 primer combinations and yielding 1,665 fragments. Phylogenies based on sequence data were reconstructed under maximum parsimony, maximum likelihood and Bayesian inference. The AFLP dataset employed minimum evolution analyses. A Monte Carlo permutation test was used to infer the influence of the geography on the phylogeny. Results Phylogenies reconstructed suggest that most genera are paraphyletic, but the phylogenetic signal may be misled by hybridization and incomplete lineage sorting. A tree with all the available molecular data shows two large clades: one of primarily Venezuelan species that includes a few neighboring Colombian species; and a second clade of only

  11. Direct and remarkably efficient conversion of methane into acetic acid catalyzed by amavadine and related vanadium complexes. A synthetic and a theoretical DFT mechanistic study.

    Science.gov (United States)

    Kirillova, Marina V; Kuznetsov, Maxim L; Reis, Patrícia M; da Silva, José A L; da Silva, João J R Fraústo; Pombeiro, Armando J L

    2007-08-29

    Vanadium(IV or V) complexes with N,O- or O,O-ligands, i.e., [VO{N(CH2CH2O)3}], Ca[V(HIDPA)2] (synthetic amavadine), Ca[V(HIDA)2], or [Bu4N]2[V(HIDA)2] [HIDPA, HIDA = basic form of 2,2'-(hydroxyimino)dipropionic or -diacetic acid, respectively], [VO(CF3SO3)2], Ba[VO(nta)(H2O)]2 (nta = nitrilotriacetate), [VO(ada)(H2O)] (ada = N-2-acetamidoiminodiacetate), [VO(Hheida)(H2O)] (Hheida = 2-hydroxyethyliminodiacetate), [VO(bicine)] [bicine = basic form of N,N-bis(2-hydroxyethyl)glycine], and [VO(dipic)(OCH2CH3)] (dipic = pyridine-2,6-dicarboxylate), are catalyst precursors for the efficient single-pot conversion of methane into acetic acid, in trifluoroacetic acid (TFA) under moderate conditions, using peroxodisulfate as oxidant. Effects on the yields and TONs of various factors are reported. TFA acts as a carbonylating agent and CO is an inhibitor for some systems, although for others there is an optimum CO pressure. The most effective catalysts (as amavadine) bear triethanolaminate or (hydroxyimino)dicarboxylates and lead, in a single batch, to CH3COOH yields > 50% (based on CH4) or remarkably high TONs up to 5.6 x 103. The catalyst can remain active upon multiple recycling of its solution. Carboxylation proceeds via free radical mechanisms (CH3* can be trapped by CBrCl3), and theoretical calculations disclose a particularly favorable process involving the sequential formation of CH3*, CH3CO*, and CH3COO* which, upon H-abstraction (from TFA or CH4), yields acetic acid. The CH3COO* radical is formed by oxygenation of CH3CO* by a peroxo-V complex via a V{eta1-OOC(O)CH3} intermediate. Less favorable processes involve the oxidation of CH3CO* by the protonated (hydroperoxo) form of that peroxo-V complex or by peroxodisulfate. The calculations also indicate that (i) peroxodisulfate behaves as a source of sulfate radicals which are methane H-abstractors, as a peroxidative and oxidizing agent for vanadium, and as an oxidizing and coupling agent for CH3CO* and that (ii) TFA is

  12. Remarks and suggestions concerned with formulation of the definition of quantity ''committed dose'' and quantity ''radiation burden'' useful in estimates of population exposure

    International Nuclear Information System (INIS)

    Cwik, T.

    1990-01-01

    The paper contains remarks to the definitions of the quantity ''commited dose'' given in the publications of the ICRP. The suggestions are presented on the mode of formulating the definition of the quantity ''commited dose'' and the definition of the quantity denoted hitherto by the symbol H 50 . The other suggestions deal with introduction of the quantity ''radiation burden'', assigned for use in assessments of irradiation expressed ''per caput'' of population. 9 refs. (author)

  13. The public prosecution's role in criminal proceedings under the rule of law: legal situation in Germany with comparative law remarks on UK and USA

    OpenAIRE

    Krey, Volker

    2009-01-01

    "Analyzing the role of Germany as a law-exporting nation the essay deals with a very specific aspect of the Rule of Lawprinciple in criminal proceedings. The author describes the division of functions among police, public prosecution and criminal courts within criminal law enforcement in Germany adding some comparative law remarks. He furthermore provides an overview of structure and organization of the public prosecution in Germany. He focuses on the relationship and interacti...

  14. A technology anthology. Recent writings and remarks on the state of the state-of-the-art.

    Science.gov (United States)

    1997-01-01

    Early this year, the Health Care Financing Administration (HCFA) backed down from plans to publish a final regulation governing the criteria for coverage of medical technologies in the Medicare program. Originally drafted in 1989, the rules spawned an eight-year controversy, largely because they proposed making "cost-effectiveness" one factor in deciding whether certain procedures would be reimbursed. It was one of the first attempts to articulate the precise role cost-effectiveness should play in coverage policy in either the public or private sectors. Many groups opposed the introduction of cost-effectiveness into the equation, but none so actively as medical device manufacturers, represented by the Health Industry Manufacturers Association (HIMA). Following are excerpts from their exchanges, beginning with HCFA's proposed rule in January of 1989.

  15. Remarks on the influence of fluorine exhalations upon the mollusks in the surroundings of Zlar nad Hronom

    Energy Technology Data Exchange (ETDEWEB)

    Lisicky, M

    1973-01-01

    Seventeen localities in the area contaminated by fluorine and its immediate vicinity were investigated. The malacocenoses in stagnant water and in the forest were most injured. Two hypothesis concerning the possible influence of hydrogen fluoride on the water-mollusks are advanced: direct effect, i.e., corrosion of the conch; and indirect effect - the HJ blocks the calcium and the only way out for the snails is to gnaw the conches. In the contaminated area the malacocenoses tend to show high dominance of one euryoecic species. 7 references.

  16. Remark on the higher order perturbative studies of flavor breaking in the standard SU(3) skyrmion quantum mechanics

    International Nuclear Information System (INIS)

    Li Jinping; Yan Mulin

    1997-01-01

    A quantitative criterion is proposed for testing the rationality of an effective QCD baryon theory. The higher order corrections of the standard SU(3) Skyrme model to the Gell-Mann-Okubo relations for baryons are studied according to the criterion, and some interesting results are presented. A possible prescription is recommended

  17. Remarkable improvement of the wear resistance of poly(vinylidene difluoride) by incorporating polyimide powder and carbon nanofibers

    Science.gov (United States)

    Min, Chunying; Liu, Dengdeng; Shen, Chen; Zhang, Qiaqia; Shen, Xiaojuan; Zhang, Kan

    2017-10-01

    Poly(vinylidene difluoride) (PVDF) composites reinforced via adding different fillers have attracted wide attention in the field of dielectric materials, but few have been reported in the tribological area. In this paper, the effect of polyimide (PI) powder and carbon nanofibers (CF) as reinforcement phases on the friction and wear performance of PVDF composites has been investigated. It was found that PI powder enhances the mechanical and tribological properties of PVDF and especially as the content of the PI powder reaches 5 wt%. In addition, CF and PI exhibited synergistic effect on the tribological properties of PVDF. With PVDF containing 5 wt% PI powder and 20 wt% CF, the friction and wear behavior of the PVDF composite showed the best performance. PVDF, PI powder and CF can form a consistent network structure, which prevents the polymer molecular chains from moving or deformation, decreasing the wear loss of PVDF composites.

  18. Fishing in dangerous waters: Remarks on a controversial appeal to spawner-recruit theory for long-term impact assessment

    International Nuclear Information System (INIS)

    Fletcher, R.I.; Deriso, R.B.

    1988-01-01

    In the Hudson River power plant case, the defending utility companies appealed to the practices of commercial fishery managers as precedent for their own uses of spawner-recruit models in forecasting the effects on stock abundances of long-term water withdrawals by the power plants. In contrast to this perception of spawner-recruit models as commonly accepted instruments of fishery management, the present survey of managers and regulatory agencies revealed instead a universal rejection of such models. The inadequacies of spawner-recruit models were attributed variously to the effects of environmental uncertainty, to imperfect knowledge of population regulation, and to the lack of sufficient biological meaning in the models themselves. In general, impact assessment little resembles fishery regulation because the options and privileges commonly exercised by a fishery manager are closed to impact management. In either case, long-term forecasting remains unreliable due to the problem, as yet unsolved, of predicting reproduction and recruitment in natural populations. 21 refs., 1 fig

  19. Remarks presented (questions/answers discussed) at public regional meetings to discuss regulations (10 CFR Part 21) for reporting of defects and noncompliance, July 12--26, 1977

    International Nuclear Information System (INIS)

    1977-09-01

    In enacting the Energy Reorganization Act of 1974, Congress included Section 206 which requires the reporting of defects and noncompliances directly to the Nuclear Regulatory Commission (NRC). This congressional action required that the NRC promulgate rules and regulations, as necessary, to assure appropriate implementation of Section 206. In response to this mandate, the NRC drafted a new regulation. Following a period of public comment and revision, the regulation identified as 10 CFR Part 21, Reporting Defects and Noncompliance, was published in a Federal Register Notice on June 6, 1977. To assist NRC licensees and other firms and organizations covered by the new Part 21 regulation, public regional meetings were conducted by staff representatives to explain the rule. At these meetings the staff presented prepared remarks and answered questions on the meaning and application of the rule. Staff remarks contained in the original publication of this document were also provided to those in attendance. At each meeting the staff received a request for the questions and answers discussed by the staff to be made available for use as guidance by the nuclear industry covered by the rule. It was announced that a consolidation of the staff position question/answer guidance would be made available to each organization or firm attending these meetings and for others where a request is made in accordance with the directions printed insidethe front cover of the document. The staff will be guided in its implementation and enforcement of Part 21 by the positions set forth in the document. The revision of NUREG-0302 includes the following three parts relating to 10 CFR Part 21: (1) remarks presented by staff representatives; (2) Federal Register Notice material; and (3) a consolidation of questions and answers from the public regional meetings

  20. Li n @B36 ( n = 1, 2) Nanosheet with Remarkable Electro-Optical Properties: A DFT Study

    Science.gov (United States)

    Solimannejad, Mohammad; Kamalinahad, Saeedeh; Shakerzadeh, Ehsan

    2017-07-01

    In this study, an attempt has been made to investigate alteration in electro-optical properties of bowl-shape B36 nanosheet due to interaction with one and two Li atoms. Our results reveal that the highest occupied molecular orbital-lowest unoccupied molecular orbital (HOMO-LUMO) gap of B36 nanosheet is decreased because of a high energy level which is formed under influence of interactions with Li atoms. Gigantic enhancement in the first hyperpolarizability ( β 0) of the studied nanosheet up to 4920.62 au is indicated owing to the effect of Li adsorption. The result of the present study may be eventuating to design and fabrication of a nanosheet with tunable electro-optical properties.

  1. Not flavone-8-acetic acid (FAA) but its murine metabolite 6-OH-FAA exhibits remarkable antivascular activities in vitro.

    Science.gov (United States)

    Pham, Minh Hien; Dauzonne, Daniel; Chabot, Guy G

    2016-06-01

    Flavone-8-acetic acid (FAA) has been proved to be a potent vascular-disrupting agent in mice. Unfortunately, FAA did not produce any anticancer activity in clinical trials. Previously, we had reported that FAA is metabolized by mouse microsomes into six metabolites, whereas it was poorly metabolized by human microsomes, with fewer metabolites formed in lesser amounts. Especially, 6-OH-FAA was not formed by human microsomes. In this work, two major available metabolites, 4'-OH-FAA and 6-OH-FAA, were tested and compared with the parent compound FAA for their potential antivascular activities in vitro. The ability of the products to induce morphological changes, disrupt preformed capillaries of EA.hy926 endothelial cells and inhibit tubulin polymerization in vitro was assessed. The action mechanism was determined using the RhoA and Rac1 inhibitors. At 25 µg/ml, 6-OH-FAA induced morphological changes and membrane blebbing, whereas 300 µg/ml of FAA and 4'-OH-FAA slightly changed the morphology without inducing membrane blebbing. At 300 µg/ml, 6-OH-FAA produced morphological changes that were 2.1-6.9-fold greater than that produced by FAA and 4'-OH-FAA, an effect that was consistent with its much greater inhibitory effect on tubulin polymerization compared with FAA and 4'-OH-FAA. 6-OH-FAA significantly disrupted the EA.hy926 cell capillaries. 6-OH-FAA activities were prevented in EA.hy926 cells pretreated with RhoA, but not Rac1, inhibitor. In this short communication we report for the first time that, in vitro, 6-OH-FAA, a mouse-specific FAA metabolite, exhibits significantly stronger antivascular activities compared with FAA and 4'-OH-FAA, which are mediated through the RhoA kinase pathway.

  2. A Correction to a Remark in a Paper by Procacci and Yuhjtman: New Lower Bounds for the Convergence Radius of the Virial Series

    Science.gov (United States)

    Procacci, Aldo

    2017-09-01

    In this note we deduce a new lower bound for the convergence radius of the Virial series of a continuous system of classical particles interacting via a stable and tempered pair potential using the estimates on the Mayer coefficients obtained in the recent paper by Procacci and Yuhjtman (Lett Math Phys 107:31-46, 2017). This corrects the wrongly optimistic lower bound for the same radius claimed (but not proved) in the above cited paper (in Remark 2 below Theorem 1). The lower bound for the convergence radius of the Virial series provided here represents a strong improvement on the classical estimate given by Lebowitz and Penrose in 1964.

  3. Remarks concerning the accurate measurement of differential cross sections for threshold reactions used in fast-neutron dosimetry for fission reactors

    International Nuclear Information System (INIS)

    Smith, D.L.

    1976-12-01

    Some remarks are submitted concerning the measurement of differential cross sections for threshold reactions which are used in fast-neutron dosimetry for fission reactors. The objective is to familiarize the reader with some of the problems associated with these measurements and, in the process, to explain why the existence of large discrepancies in the data sets for many of these reactions is not surprising. Limits to the accuracy which can be expected for these cross sections in the near future--using current technology and available resources--are examined in a general way and recommendations for improving the accuracy of the differential data base for dosimetry reactions are presented

  4. Enhanced binding affinity, remarkable selectivity, and high capacity of CO 2 by dual functionalization of a rht-type metal-organic framework

    KAUST Repository

    Li, Baiyan

    2011-12-23

    Open and friendly: The smallest member of the rht-type metal-organic frameworks (MOFs, see picture) constructed by a hexacarboxylate ligand with a nitrogen-rich imino triazine backbone shows a significantly enhanced gas binding affinity relative to all other isoreticular rht-type MOFs. The high adsorption capacity and remarkable selectivity of CO 2 are attributed to the high density of open metal and Lewis basic sites in the framework. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Summary remarks and recommended reactions for an international data file for dosimetry applications for LWR, FBR, and MFR reactor research, development and testing programs

    International Nuclear Information System (INIS)

    McElroy, W.N.; Lippincott, E.P.; Grundl, J.A.; Fabry, A.; Dierckx, R.; Farinelli, U.

    1979-01-01

    The need for the use of an internationally accepted data file for dosimetry applications for light water reactor (LWR), fast breeder reactor (FBR), and magnetic fusion reactor (MFR) research, development, and testing programs continues to exist for the Nuclear Industry. The work of this IAEA meeting, therefore, will be another important step in achieving consensus agreement on an internationally recommended file and its purpose, content, structure, selected reactions, and associated uncertainy files. Summary remarks and a listing of recommended reactions for consideration in the formulation of an ''International Data File for Dosimetry Applications'' are presented in subsequent sections of this report

  6. [Quantifying the additional clinical benefit of new medicines: little - considerable - significant - 6 remarks from a biometrician's point of view].

    Science.gov (United States)

    Vach, Werner

    2014-11-01

    According to the German Pharmaceutical Market Reorganisation Act [Arzneimittelmarktneuordnungsgesetz (AMNOG)] of 22.12.2010, the benefit assessment of a new drug should include an evaluation of the "degree of additional benefit". A corresponding regulation of the German Ministry of Health states that the quantification of the degree of additional benefit should be made in the terms "major additional benefit", "considerable additional benefit" and "little additional benefit". In September 2011 the IQWiG undertook and explained in appendix A of the dossier evaluation of Ticagrelor an "operationalisation of the extent of additional benefit according to AM-NutzenV". Therein a distinction was made between the target categories "survival time (mortality)", "serious (or, respectively, severe) symptoms", "quality of life", and "not serious (or, respectively, not severe) symptoms". In the operationalisation of the IQWiG, the categorisation of the additional benefit with regard to mortality was addressed by definition of threshold values for the upper limit of the 95% confidence interval for the relative risk (RR). The statutory regulations and the operationalisation of the IQWiG will have direct long-term effects on the provision of medical care since they have a say as to which drugs are to be available at which prices. By introduction of terms such as "major additional benefit", "considerable additional benefit" or "desired effects" and linking them to statistical parameters and algorithms, they also open a series of further fundamental questions as to if and how we should handle these terms in the future and what consequences are inherent to the use of statistical criteria in their "definition". In the present article 6 of the questions that arise in this context are discussed: Can a "considerable additional benefit" be defined with statistical methods? Can a classification of the additional benefit on the basis of an estimated RR be reliable? What are the fundamental

  7. The remarkable metrological history of 14C dating: from ancient Egyptian artifacts to particles of soot and grains of pollen

    International Nuclear Information System (INIS)

    Currie, L.A.

    2003-01-01

    Radiocarbon dating would not have been possible if 14 C had not had the 'wrong' half-life - a fact that delayed its discovery. Following the discovery of this 5730 year radionuclide in laboratory experiments by Ruben and Kamen, it became clear to W. F. Libby that 14 C should exist in nature, and that it could serve as a quantitative means for dating artifacts and events marking the history of civilization. The search for natural radiocarbon was a metrological challenge; the level in the living biosphere (ca. 230 Bq/kg) lay far beyond the then current state of the measurement art. This article traces the metrological history of radiocarbon, from the initial breakthrough devised by Libby, to minor (evolutionary) and major (revolutionary) advances that have brought 14 C measurement from a crude, bulk (8 g carbon) dating tool, to a refined probe for dating tiny amounts of precious artifacts, and for 'molecular dating' at the 10 μg to 100 mg level. The metrological advances led to opportunities and surprises, such as the non-monotonic dendrochronological calibration curve and the 'bomb effect', that spawned new multidisciplinary areas of application, ranging from cosmic ray physics to oceanography to the reconstruction of environmental history. (author)

  8. IAEA Director General's concluding remarks. Meeting of the Contracting Parties to the Convention on Nuclear Safety. Vienna, 26 April 2002

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2002-01-01

    The Convention on Nuclear Safety is considered as a part of the overall nuclear safety regime. That regime has many components, but they all have one single objective - to make sure that safety is at as high a level as possible. The Convention is a living process, a process which should eventually lead to increasingly greater safety. The Meting has focused on a number of issues that are also priorities for the Agency; one such issue is safety culture. The effectiveness and transparency are key issues. A second issue which is highlighted is management of nuclear knowledge. Other high priority issues which were identified include: planned life extension; the need during life extension to look into the ageing of equipment and structures; deregulation and its impact on safety; and the question of periodic safety reviews. The question of co-operation between regulatory bodies is one that was given emphasis to over the last few years. It is very important that there be exchange of experience and exchange of expertise between regulatory bodies, and between the manufacturers of power reactors and the countries where the reactors are operated. Also of importance in terms of international co-operation is the development of adequate emergency response everywhere. A major point that which is left to the participating countries is that although safety is a national responsibility - there is absolutely no question about that -many issues need international co-operation

  9. Remarkable Electromechanical Coupling in the 2–2 Composite Based on Single-domain PMN–0.33PT Crystal

    Directory of Open Access Journals (Sweden)

    Vitaly Yu. TOPOLOV

    2009-10-01

    Full Text Available A novel parallel-connected 2–2 single-domain 0.67Pb(Mg1/3Nb2/3O3 – 0.33PbTiO3 crystal / polymer composite with various orientations of polarization vectors of the components is proposed to analyze behavior of electromechanical coupling factors k*3j and k*k where j = 1, 2 and 3. It is shown that the combination of the highly piezo-active relaxor-ferroelectric single-domain component and the piezoelectric polymer provides considerable values of k*k (min k*k » –0.8 and max k*k» 0.7 and |k*33| (about 0.9. The active role of the polarization orientation effect and the composite structure in attaining the high performance is emphasized in this work. A strong correlation between k*k and the hydrostatic piezoelectric coefficient is first revealed near min k*k and max k*k of the 2–2 composite. Some advantages concerned with the presence of the single-domain component in the 2–2 composite are discussed in connection with the large values of k*3j and k*k as well as with the considerable anisotropy of k*3j.

  10. The remarkable metrological history of 14C dating: From ancient Egyptian artifacts to particles of soot and grains of pollen

    Science.gov (United States)

    Currie, L. A.

    2003-01-01

    Radiocarbon dating would not have been possible if 14C had not had the “wrong” half-life—a fact that delayed its discovery [1]. Following the discovery of this 5730 year radionuclide in laboratory experiments by Ruben and Kamen, it became clear to W. F. Libby that 14C should exist in nature, and that it could serve as a quantitative means for dating artifacts and events marking the history of civilization. The search for natural radiocarbon was a metrological challenge; the level in the living biosphere [ca. 230 Bq/kg] lay far beyond the then current state of the measurement art. This article traces the metrological history of radiocarbon, from the initial breakthrough devised by Libby, to minor (evolutionary) and major (revolutionary) advances that have brought 14C measurement from a crude, bulk [8 g carbon] dating tool, to a refined probe for dating tiny amounts of precious artifacts, and for “molecular dating” at the 10 μg to 100 μg level. The metrological advances led to opportunities and surprises, such as the non-monotonic dendrochronological calibration curve and the “bomb effect,” that spawned new multidisciplinary areas of application, ranging from cosmic ray physics to oceanography to the reconstruction of environmental history.

  11. Preventing maritime transport of pathogens: the remarkable antimicrobial properties of silver-supported catalysts for ship ballast water disinfection.

    Science.gov (United States)

    Theologides, C P; Theofilou, S P; Anayiotos, A; Costa, C N

    2017-07-01

    Ship ballast water (SBW) antimicrobial treatment is considered as a priority issue for the shipping industry. The present work investigates the possibility of utilizing antimicrobial catalysis as an effective method for the treatment of SBW. Taking into account the well-known antimicrobial properties of ionic silver (Ag + ), five silver-supported catalysts (Ag/γ-Al 2 O 3 ) with various loadings (0.05, 0.1, 0.2, 0.5, and 1 wt%) were prepared and examined for the antimicrobial treatment of SBW. The bactericidal activity of the aforementioned catalysts was investigated towards the inhibition of Escherichia coli (Gram-negative) and Escherichia faecalis (Gram-positive) bacteria. Catalytic experiments were conducted in a three-phase continuous flow stirred tank reactor, used in a semi-batch mode. It was found that using the catalyst with the lowest metal loading, the inhibition of E. coli reached 95.8% after 30 minutes of treatment of an E. coli bacterial solution, while the inhibition obtained for E. faecalis was 76.2% after 60 minutes of treatment of an E. faecalis bacterial solution. Even better results (100% inhibition after 5 min of reaction) were obtained using the catalysts with higher Ag loadings. The results of the present work indicate that the prepared monometallic catalysts exert their antimicrobial activity within a short period of time, revealing, for the first time ever, that the field of antimicrobial heterogeneous catalysis using deposited ionic silver on a solid support may prove decisive for the disinfection of SBW.

  12. On a Particular Aspect of the Identification of Tibetan Xylographs: Preliminary Remarks on the Importance of Craftsmen

    Directory of Open Access Journals (Sweden)

    Michela Clemente

    2017-07-01

    Full Text Available This essay briefly discusses the early history of Tibetan printing by comparing some facets of this subject with the European phenomenon. Printing started to be a means of dissemination of texts in Tibet and Europe at roughly the same time. Recent research indicates that although printing in Tibet does not seem to have had the kind of socially transformative effects highlighted in Elisabeth Eisenstein’s study, it did have some important consequences and also similarities with the European printing history. This article also presents a Marie Sklodowska Curie project on Tibetan xylographs entitled Tibetan Book Evolution and Technology (TiBET, which was carried out at the University of Cambridge (Mongolia and Inner Asia Studies Unit from 2013 to 2015. This paper focuses in particular on one of the aspects of the above-mentioned project, that is to say, the craftsmen who worked on sixteenth century xylographs and their importance for the identification of Tibetan prints. These artists were allowed to sign their work, a peculiarity that was typical of the earliest stage of printing and is extremely relevant for locating the printing house where a certain xylograph was produced. By comparing the different signatures and patterns of carving, writing or drawing, we might learn to distinguish the diverse style of each artist. This would help us in identifying those who worked on xylographs that lack signatures and do not mention them in colophons. From these prints we can also extract information about the craftsmen and the printing projects with which they were associated.

  13. Opening remarks at the International Conference on the Safety and Security of Radioactive Sources, Bordeaux, France, 27 June 2005

    International Nuclear Information System (INIS)

    Taniguchi, T.

    2005-01-01

    The vast majority of radioactive sources are controlled properly. However, radiological accidents have occurred in all regions of the world - which indicates that there is not always sufficient control of sources throughout their life cycle. Even advanced countries with developed regulatory systems lose track of sources each year resulting in orphan sources with the potential to cause incidents or accidents. Actually, an increasing number of cases of uncontrolled movement of sources are reported the Agency's Illicit Trafficking Database (ITDB). The International Conference on Security of Radioactive Sources, held in Vienna, Austria, in 2003, addressed these concerns and called for international initiatives, including the updating of the IAEA Action Plan for the Safety and Security of Radioactive Sources. As a direct result of the updated Action Plan the Code of Conduct on the Safety and Security of Radioactive Sources was revised and approved by the Board of Governors in 2003, its supporting Guidance on the Import and Export of Radioactive Sources was developed and approved in 2004 and the Safety Guide on Categorization of Radioactive Sources was completed recently. All three documents were developed under the auspices of the IAEA to achieve international consensus and they play a central role in this Conference. It is worth noting that more than 70 countries have already expressed their intention to follow the guidance given in the Code of Conduct on the Safety and Security of Radioactive Sources - and I would like to encourage more countries to do so. The Agency has been promoting for some time now the idea of a Global Nuclear Safety Regime. At the heart of this regime is a strong and effective national safety infrastructure where - as an overriding priority - safety issues are given the attention warranted by their significance. The need for sustainable regulatory infrastructure for the safety and security of radioactive sources was discussed at the

  14. Fundamental equations for two-phase flow. Part 1: general conservation equations. Part 2: complement and remarks

    International Nuclear Information System (INIS)

    Delhaye, J.M.

    1968-12-01

    This report deals with the general equations of mass conservation, of momentum conservation, and energy conservation in the case of a two-phase flow. These equations are presented in several forms starting from integral equations which are assumed initially a priori. 1. Equations with local instantaneous variables, and interfacial conditions; 2. Equations with mean instantaneous variables in a cross-section, and practical applications: these equations include an important experimental value which is the ratio of the cross-section of passage of one phase to the total cross-section of a flow-tube. 3. Equations with a local statistical mean, and equations averaged over a period of time: A more advanced attempt to relate theory and experiment consists in taking the statistical averages of local equations. Equations are then obtained involving variables which are averaged over a period of time with the help of an ergodic assumption. 4. Combination of statistical averages and averages over a cross-section: in this study are considered the local variables averaged statistically, then averaged over the cross-section, and also the variables averaged over the section and then averaged statistically. 5. General equations concerning emulsions: In this case a phase exists in a locally very finely divided form. This peculiarity makes it possible to define a volume concentration, and to draw up equations which have numerous applications. - Certain points arising in the first part of this report concerning general mass conservation equations for two-phase flow have been completed and clarified. The terms corresponding to the interfacial tension have been introduced into the general equations. The interfacial conditions have thus been generalized. A supplementary step has still to be carried out: it has, in effect, been impossible to take the interfacial tension into account in the case of emulsions. It was then appeared interesting to compare this large group of fundamental

  15. Remarkable stability in patterns of blood-stage gene expression during episodes of non-lethal Plasmodium yoelii malaria.

    Science.gov (United States)

    Cernetich-Ott, Amy; Daly, Thomas M; Vaidya, Akhil B; Bergman, Lawrence W; Burns, James M

    2012-08-06

    blood-stage infection regardless of experimental condition. Taken together, these results indicate that 1) P. yoelii gene expression remains stable in the presence of a changing host environment, and 2) concurrent expression of a large number of the polymorphic yir and pyst-a genes, rather than differential expression in response to specific host factors, may in itself limit the effectiveness of host immune responses.

  16. Remarkable changes in interface O vacancy and metal-oxide bonds in amorphous indium-gallium-zinc-oxide thin-film transistors by long time annealing at 250 °C

    Energy Technology Data Exchange (ETDEWEB)

    Chowdhury, Md Delwar Hossain; Um, Jae Gwang; Jang, Jin, E-mail: jjang@khu.ac.kr [Advanced Display Research Center and Department of Information Display, Kyung Hee University, Seoul 130-701 (Korea, Republic of)

    2014-12-08

    We have studied the effect of long time post-fabrication annealing on negative bias illumination stress (NBIS) of amorphous indium-gallium-zinc-oxide (a-IGZO) thin-film-transistors. Annealing for 100 h at 250 °C increased the field effect mobility from 14.7 cm{sup 2}/V s to 17.9 cm{sup 2}/V s and reduced the NBIS instability remarkably. Using X-ray photoelectron spectroscopy, the oxygen vacancy and OH were found to exist at the interfaces of a-IGZO with top and bottom SiO{sub 2}. Long time annealing helps to decrease the vacancy concentration and increase the metal-oxygen bonds at the interfaces; this leads to increase in the free carrier concentrations in a-IGZO and field-effect mobility. X-ray reflectivity measurement indicated the increment of a-IGZO film density of 5.63 g cm{sup −3} to 5.83 g cm{sup −3} (3.4% increase) by 100 h annealing at 250 °C. The increase in film density reveals the decrease of O vacancy concentration and reduction of weak metal-oxygen bonds in a-IGZO, which substantially helps to improve the NBIS stability.

  17. Remarkable changes in interface O vacancy and metal-oxide bonds in amorphous indium-gallium-zinc-oxide thin-film transistors by long time annealing at 250 °C

    International Nuclear Information System (INIS)

    Chowdhury, Md Delwar Hossain; Um, Jae Gwang; Jang, Jin

    2014-01-01

    We have studied the effect of long time post-fabrication annealing on negative bias illumination stress (NBIS) of amorphous indium-gallium-zinc-oxide (a-IGZO) thin-film-transistors. Annealing for 100 h at 250 °C increased the field effect mobility from 14.7 cm 2 /V s to 17.9 cm 2 /V s and reduced the NBIS instability remarkably. Using X-ray photoelectron spectroscopy, the oxygen vacancy and OH were found to exist at the interfaces of a-IGZO with top and bottom SiO 2 . Long time annealing helps to decrease the vacancy concentration and increase the metal-oxygen bonds at the interfaces; this leads to increase in the free carrier concentrations in a-IGZO and field-effect mobility. X-ray reflectivity measurement indicated the increment of a-IGZO film density of 5.63 g cm −3 to 5.83 g cm −3 (3.4% increase) by 100 h annealing at 250 °C. The increase in film density reveals the decrease of O vacancy concentration and reduction of weak metal-oxygen bonds in a-IGZO, which substantially helps to improve the NBIS stability

  18. Remarkable promoting effect of rhodium on the catalytic performance of Ag/Al2O3 for the selective reduction of NO with decane

    International Nuclear Information System (INIS)

    Sato, Kazuhito; Yoshinari, Tomohiro; Kintaichi, Yoshiaki; Haneda, Masaaki; Hamada, Hideaki

    2003-01-01

    The addition of small amounts of rhodium enhanced the activity of Ag/Al 2 O 3 catalyst for the selective reduction of NO with decane at low temperatures. The Rh-promoted Ag/Al 2 O 3 showed its high performance even in the presence of low concentrations of SO 2 . Based on the catalytic activity for elementary reactions, it was suggested that the role of added rhodium is to enhance the reaction between NO x and decane-derived species, leading to NO reduction. Catalyst characterization by UV-Vis spectroscopy indicated that the major silver species on Rh-promoted Ag/Al 2 O 3 is Ag nn δ+ clusters, which would be responsible for the high activity. FT-IR measurements revealed that the formation rate of isocyanate species, which is a major reaction intermediate, is higher on Rh-promoted Ag/Al 2 O 3

  19. Nuclear industry and legal security - some remarks on the restrictive effects on legal protection and participation of the public in the nuclear system

    International Nuclear Information System (INIS)

    Baumann, W.

    1989-01-01

    The state is on dangerous ground with the development that can be observed in the legal field, allowing legal protection against large-scale technology and projects, particularly in the nuclear sector, to be gradually cut back. This impression is shown to be true first of all in relation to legislation which reduced legal protection through the instrument of judicial review, for protection of life and health from technological hazards, to the functions of a trial court, and this for reasons of opportunistic and short-term political interests. Decisions of the Federal Administrative Court in nuclear law matters have been neglecting the principle of legal protection to an extent that the legitimation quality of decisions in this field of law has been diminishing more than can be expected at first sight, looking at the restrictions. The public has come to realise that the courts content themselves with reviewing only a small part of the case and close their eyes to the concerns of the public, which in turn loses trust in the sincerity of judicial proceedings and the correctness of court decisions. The citizen will turn to other ways and means in order to come into his own. This is a dangerous development in a constitutional state, and must be prevented. (orig./HSCH) [de

  20. OsO(4) in ionic liquid [Bmim]PF(6): a recyclable and reusable catalyst system for olefin dihydroxylation. remarkable effect of DMAP.

    Science.gov (United States)

    Yao, Qingwei

    2002-06-27

    [reaction: see text] The combination of the ionic liquid [bmim]PF(6) and DMAP provides a most simple and practical approach to the immobilization of OsO(4) as catalyst for olefin dihydroxylation. Both the catalyst and the ionic liquid can be repeatedly recycled and reused in the dihydroxylation of a variety of olefins with only a very slight drop in catalyst activity.

  1. Welcoming Address & Opening Remarks [International Conference on Research Reactors: Safe Management and Effective Utilization, Vienna (Austria), 16-20 November 2015

    International Nuclear Information System (INIS)

    Chudakov, M.

    2017-01-01

    For more than 60 years, research reactors have been centres of innovation and productivity for nuclear science and technology programmes in 67 countries around the world. Research reactors provide a multidisciplinary environment to catalyse scientific, industrial, medical and agricultural development. They are facilities for nuclear education and training of young scientists and technicians, and they can contribute to the development of nuclear power programmes. According to the IAEA Research Reactor Database, there are 246 research reactors currently in operation in 55 countries, and close to 30 new research reactor projects are at different stages of implementation. Many of the operating reactors are several decades old and face ageing management issues. These reactors must be operated and maintained with due regard to safety and security. Some reactors face challenges with sustainable supply of fresh fuel. Others are looking to improve utilization, which is linked to justifying adequate resources for operation, maintenance and refurbishment. As some of the fuel return programmes are expected to wind down in the near term, the community will need to find solutions for spent fuel and waste management. And taking into account the large number of reactors, about 140, no longer in operation, as well as ageing reactors coming to the end of their lifecycles, decommissioning is an important area of sharing experience and best practice. You will have an opportunity to discuss these and other issues over the course of the conference.

  2. The quantitative description of radiation-unduced cell inactivation. 9. Some remarks on the relative biological effect of ionizing radiation upon reproductive death of diploid and polyploid cells

    International Nuclear Information System (INIS)

    Barsukov, V.S.; Malinovskij, O.V.

    1978-01-01

    A model of repproductive death of cells is suggested and tested on the basis of data on relative biological efficiency (RBE) with provision for microdosimetry approaches. The model considers irradiation of cells with charged particles under conditions of linear energy transfers (LET) to the cell nucleus by a particle. This energy is subject to great fluctuations, and irradiation of a cell should be characterized not by the absorbed dose but rather by its stochastic analogue - specific energy. It appears then that RBE should be determined from the specific energy-response relationshjp rather than from dose-response relationship. The followjng main results were obtained: experimental relationship between the yield of sublesions, one-track and two-track lethals and LET correspond to that expected from the literature data; under the conditions considered, RBE can be determined from absorbed dose-pesponse dependency; RBE for sublesions, one- and two-track lethals taken separatly does not depend on the radiation dose and the relationshjp between the resulting RBE and the response is governed by redistribution of contributions of one- and two-track lethals at different doses. The plausibility of the model suggested is thus confirmed

  3. Concluding remarks to ICAME2011

    International Nuclear Information System (INIS)

    Campbell, S. J.

    2012-01-01

    An overview of the main aspects of ICAME2011 – tutorial lectures, oral and poster presentations, evening sessions - is presented along with a brief outline of several of the scientific highlights. Among other topics considered are the involvements of young scientists and female scientists, and operation of the oral and poster sessions. Despite the most challenging combinations of circumstances in the lead up to ICAME2011 that resulted in the change of venue at an advanced stage from Tokyo to Kobe, the Committee organised a high quality conference with many positive outcomes for the future. The Mössbauer community acknowledges and appreciates these efforts greatly.

  4. Concluding remarks on future facilities

    International Nuclear Information System (INIS)

    Jean-Marie, B.

    1989-12-01

    The principles of some of the facilities and projects for the study of hadron spectroscopy are summarized. The work is focalized on e + e - machines, which are classified according to the quark family they can study: U,D,S quark families, C quark and τ studies and B quark family. The analysis leads to the conclusion that high luminosity e + e - machines are needed to progress in the hadron spectroscopy exploration

  5. Some remarks on modeling uncertainties

    International Nuclear Information System (INIS)

    Ronen, Y.

    1983-01-01

    Several topics related to the question of modeling uncertainties are considered. The first topic is related to the use of the generalized bias operator method for modeling uncertainties. The method is expanded to a more general form of operators. The generalized bias operator is also used in the inverse problem and applied to determine the anisotropic scattering law. The last topic discussed is related to the question of the limit to accuracy and how to establish its value. (orig.) [de

  6. Remarks on finite W algebras

    International Nuclear Information System (INIS)

    Barbarin, F.; Sorba, P.; Ragoucy, E.

    1996-01-01

    The property of some finite W algebras to be the commutant of a particular subalgebra of a simple Lie algebra G is used to construct realizations of G. When G ≅ so (4,2), unitary representations of the conformal and Poincare algebras are recognized in this approach, which can be compared to the usual induced representation technique. When G approx=(2, R), the anyonic parameter can be seen as the eigenvalue of a W generator in such W representations of G. The generalization of such properties to the affine case is also discussed in the conclusion, where an alternative of the Wakimoto construction for sl(2) k is briefly presented. (authors)

  7. Some remarks on conditional entropy

    NARCIS (Netherlands)

    Nijst, A.G.P.M.

    1969-01-01

    Using a definition of conditional entropy given by Hanen and Neveu [5, 10, 11] we discuss in this paper some properties of conditional entropy and mean entropy, in particular an integral representation of conditional entropy (§ 2), and the decomposition theorem of the KolmogorovSina¯i invariant (§

  8. Some remarks on good sets

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    A subset S of is said to be full, if S is a maximal good set in 1S × 2S ืทททื nS. ([3], p. 183). Two points .... assume there is a p for which |np|= |mp|. Then. ∑k j=1 nj xj = 0 ..... M G Nadkarni for suggesting the problems and for encouragement and ...

  9. Some remarks on farthest points

    Czech Academy of Sciences Publication Activity Database

    Montesinos, V.; Zizler, P.; Zizler, Václav

    2011-01-01

    Roč. 105, č. 1 (2011), s. 119-131 ISSN 1578-7303 R&D Projects: GA AV ČR IAA100190901 Institutional research plan: CEZ:AV0Z10190503 Keywords : farthest points * strongly exposed points * generic differentiability * convex functions Subject RIV: BA - General Mathematics Impact factor: 0.340, year: 2011 http://link.springer.com/article/10.1007%2Fs13398-011-0012-z

  10. Some remarks on software reliability

    International Nuclear Information System (INIS)

    Gonzalez Hernando, J.; Sanchez Izquierdo, J.

    1978-01-01

    Trend in modern NPPCI is toward a broad use of programmable elements. Some aspects concerning present status of programmable digital systems reliability are reported. Basic differences between software and hardware concept require a specific approach in all the reliability topics concerning software systems. The software reliability theory was initialy developed upon hardware models analogies. At present this approach is changing and specific models are being developed. The growing use of programmable systems necessitates emphasizing the importance of more adequate regulatory requirements to include this technology in NPPCI. (author)

  11. Remark on Trautman's Radiation Condition

    International Nuclear Information System (INIS)

    Walker, M.

    1979-01-01

    The confusion about the boundary conditions for radiating systems formulated by Trautman are discussed. The confusion has mainly to do with where in space-time the conditions are to be imposed but also with what is it that the conditions are intended to guarantee. Imposing Trautman's conditions near future null infinity allows the existence of outgoing radiation; in order to exclude incoming radiation, they must be imposed near (or at) past null infinity. Since receding to infinity in spacelike directions means that one crosses all radiation, whether in- or outgoing, it makes no sense to impose the conditions at spatial infinity. If one were to impose fall-off of the electromagnetic field in flat space-time of 1/n at spatial infinity, then the field would contain finite energy. (Auth.)

  12. New remarks on chiral bosonization

    International Nuclear Information System (INIS)

    Souza Dutra, A. de

    1992-01-01

    We discuss a certain duality between the constraints appearing in ordinary Lagrangian density and its first order counterpart for the gauged Siegel chiral boson. It is demonstrated the equivalence, at the classical level, of the two versions of the gauged Siegel chiral boson to its corresponding gauged Floreanini-Jackiw chiral bosons. It is also argued that the most general constrained Lagrangian density, that leads to a bosonic field obeying a first order differential equation of motion and preserve simultaneously Lorentz invariance, is just the Floreanini-Jackiw one. (author)

  13. Editorial Remarks: Youth at Risk

    Directory of Open Access Journals (Sweden)

    Steven F. Messner

    2011-12-01

    Full Text Available

    Youth must always be analysed with respect to two aspects: Firstly, as a societally shaped phase of life that varies socially and culturally across countries and regions, characterized by different chances of social integration and dangers of disintegration. Secondly, as individual biographies playing out in a specific societal dynamic of integration/disintegration, where experiences with violence as perpetrators or victims play an important role. 

    Life in particular societal constellations presents risks for certain parts of the young generation, just as the behavior of youth may itself pose risks in some societal situations. The way the general relationship varies across different national and cultural contexts is the question we have chosen to home in on in this issue of the journal. Post-war, post-dictatorial, developing, transformative, and precarious societal contexts form consistent points of reference for the contributions, which include both country-specific case studies and comparative investigations.

  14. Energy taxes -- Some critical remarks

    International Nuclear Information System (INIS)

    Wirl, F.

    1994-01-01

    The familiar concept of Pigouvian taxes has finally caught the interest of politicians as the various proposals for a pollution tax, often simplified to an energy tax, document. This paper reviews these proposals critically and points at some wrong presumptions. The suggestion to make the polluter liable for all damages is in general inefficient. In order to sell new taxes, politicians argue that Pigouvian taxes would not lower disposable income, because the associated revenues allow one to reduce other taxes (in particular, income taxes) correspondingly. However, strategic, noncompetitive energy producers may themselves attempt to internalize the external costs rather than to leave these tax revenues to the treasuries of the consuming countries. Moreover, the revenues from a commodity tax are potentially volatile. Finally, the conservation impact from Pigouvian energy taxes may fall short of expectations, in particular, if the tax is too low

  15. Quark Matter '87: Concluding remarks

    International Nuclear Information System (INIS)

    Gyulassy, M.

    1988-03-01

    This year marked the beginning of the experimental program at BNL and CERN to probe the properties of ultra dense hadronic matter and to search for the quark-gluon plasma phase of matter. Possible implications of the preliminary findings are discussed. Problems needing further theoretical and experimental study are pointed out. 50 refs

  16. Remarks On General Fibonacci Numbers

    OpenAIRE

    Billal, Masum

    2015-01-01

    We dedicate this paper to investigate the most generalized form of Fibonacci Sequence, one of the most studied sections of the mathematical literature. One can notice that, we have discussed even a more general form of the conventional one. Although it seems the topic in the first section has already been covered before, but we present a different proof here. Later I found out that, the auxiliary theorem used in the first section was proven and even generalized further by F. T. Howard. Thanks...

  17. Remarks on Bishop - type operators

    Czech Academy of Sciences Publication Activity Database

    Ambrozie, Calin-Grigore

    2010-01-01

    Roč. 59, č. 1 (2010), s. 5-16 ISSN 1010-5433 R&D Projects: GA ČR(CZ) GA201/06/0128; GA AV ČR IAA100190903 Institutional research plan: CEZ:AV0Z10190503 Keywords : invariant subspace * irrational rotation Subject RIV: BA - General Mathematics http://fmi.unibuc.ro/ro/anale/ matematica /1_2010/ambrozie.pdf

  18. Remarks on the thorium cycle

    International Nuclear Information System (INIS)

    Teller, E.

    1978-01-01

    The use of thorium and neutrons to make 233 U would provide energy for many thousands of years. Thorium is more abundant than uranium and 233 U is the best fissile material for thermal neutron reactors. Four approaches to the use of thorium are worth developing: heavy water moderated reactors with conversion ratios greater than 0.9, such as modified CANDU with lower cost of separating D 2 O and 235 U; molten salt breeder reactors, from which fission products and excess fuel may be continuously removed; fusion-fission hybrids that produce adequate tritium and excess neutrons for sustenance and 233 U production in a subcritical thorium 233 U blanket; and by fission-initiated thermo-nuclear explosions in cavities in salt beds one mile below the earth's surface, yielding 233 U from the excess neutrons and thorium and decontaminated steam for power production. (author)

  19. Remarks on lattice gauge models

    International Nuclear Information System (INIS)

    Grosse, H.

    1981-01-01

    The author reports a study of the phase structure of lattice gauge models where one takes as a gauge group a non-abelian discrete subgroup of SU(3). In addition he comments on a lattice action proposed recently by Manton and observes that it violates a positivity property. (Auth.)

  20. Methodological remarks on contraction theory

    DEFF Research Database (Denmark)

    Jouffroy, Jerome; Slotine, Jean-Jacques E.

    Because contraction analysis stems from a differential and incremental framework, the nature and methodology of contraction-based proofs are significantly different from those of their Lyapunov-based counterparts. This paper specifically studies this issue, and illustrates it by revisiting some c...... classical examples traditionally addressed using Lyapunov theory. Even in these cases, contraction tools can often yield significantly simplified analysis. The examples include adaptive control, robotics, and a proof of convergence of the deterministic Extended Kalman Filter....

  1. Remarks on lattice gauge models

    International Nuclear Information System (INIS)

    Grosse, H.

    1981-01-01

    The author reports on a study of the phase structure of lattice gauge models where one takes as a gauge group a non-abelian discrete subgroup of SU(3). In addition he comments on a lattice action proposed recently by Manton (1980) and observes that it violates a positivity property. (Auth.)

  2. Critical remark on Jauch's program

    International Nuclear Information System (INIS)

    Hadjisavvas, N.; Thieffine, F.; Mugur-Schaechter, M.

    1981-01-01

    It is shown by means of a simple example that Jauch's program of recovering the Hilbert space formulation of quantum mechanics from structures of empirically defined entities is not realized. (author)

  3. Remarks on the maximum luminosity

    Science.gov (United States)

    Cardoso, Vitor; Ikeda, Taishi; Moore, Christopher J.; Yoo, Chul-Moon

    2018-04-01

    The quest for fundamental limitations on physical processes is old and venerable. Here, we investigate the maximum possible power, or luminosity, that any event can produce. We show, via full nonlinear simulations of Einstein's equations, that there exist initial conditions which give rise to arbitrarily large luminosities. However, the requirement that there is no past horizon in the spacetime seems to limit the luminosity to below the Planck value, LP=c5/G . Numerical relativity simulations of critical collapse yield the largest luminosities observed to date, ≈ 0.2 LP . We also present an analytic solution to the Einstein equations which seems to give an unboundedly large luminosity; this will guide future numerical efforts to investigate super-Planckian luminosities.

  4. A Remark on Dilaton Stabilization

    CERN Document Server

    Dvali, Gia; Dvali, Gia; Kakushadze, Zurab

    1998-01-01

    Dilaton stabilization may occur in a theory based on a single asymptotically free gauge group with matter due to an interplay between quantum modification of the moduli space and tree-level superpotential. We present a toy model where such a mechanism is realized. Dilaton stabilization in this mechanism tends to occur at strong coupling values unless some unnatural adjustment of parameters is involved.

  5. The remarkable discreteness of being

    Indian Academy of Sciences (India)

    2014-03-15

    Mar 15, 2014 ... In biology, the theory of Darwinian evolution was inconsistent with the then obvious blending theory ..... A self-consistent model of geographical ... Wilson model and can be put to experimental verification. Improving the above ...

  6. Windpower `96 opening session remarks

    Energy Technology Data Exchange (ETDEWEB)

    Ervin, C.A.

    1996-12-31

    Opinions on political factors affecting the U.S. market for wind power are presented in this paper. The position of the Assistant Secretary of the Energy Efficiency and Renewable Energy Division of the U.S. Department of Energy is stated. Political aspects of renewable energy sources are reviewed. The link between clean energy sources and a clean environment is discussed. The role of the Federal Government in promoting clean energy sources is also discussed.

  7. Remarks on network public theory

    OpenAIRE

    Marcin Brol; Slawomir Czetwertynski

    2013-01-01

    This paper is a trial of capturing of a relation between traditional public sphere atrophy and the augmentation of a network public sphere. A thesis is advanced that the traditional public sphere is subject of the atrophy, however, the entire network public sphere is subject of the augmentation process. Such a formulated thesis forces a choice between two following issues. The first of them regards a relation between factors, which stimulate the atrophy and the augmentation. The second issue ...

  8. Concluding remarks for ECRIS '02

    International Nuclear Information System (INIS)

    Lyneis, Claude

    2002-01-01

    ECRIS'02 was held in Jyvaeskylae Finland at the edge of Lake Jyvaeskylae, which was beautiful location to meet and discuss the state of Electron Cyclotron Resonance ion sources. It was the 15th ECR Ion Source Workshop in a series stretching back to the first workshop held November 6, 1978 in Karlsruhe Germany. Overall, the workshop reports could be characterized as showing solid achievements and steady progress without any spectacular breakthroughs or highly controversial new ideas. In this short report, I will mention some of the highlights and surprises of the workshop that I observed during the meeting and reported on at the close of the meeting. As such, it will be relatively brief and not meant to be all encompassing. A short list of items that made this workshop memorable is given

  9. Concluding remarks to ICAME2011

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, S. J., E-mail: Stewart.Campbell@adfa.edu.au [University of New South Wales, School of Physical, Environmental and Mathematical Sciences (Australia)

    2012-03-15

    An overview of the main aspects of ICAME2011 - tutorial lectures, oral and poster presentations, evening sessions - is presented along with a brief outline of several of the scientific highlights. Among other topics considered are the involvements of young scientists and female scientists, and operation of the oral and poster sessions. Despite the most challenging combinations of circumstances in the lead up to ICAME2011 that resulted in the change of venue at an advanced stage from Tokyo to Kobe, the Committee organised a high quality conference with many positive outcomes for the future. The Moessbauer community acknowledges and appreciates these efforts greatly.

  10. Closing remarks for ECRIS'10

    International Nuclear Information System (INIS)

    Nakagawa, T.

    2012-01-01

    The scientific topics of the ECRIS 2010 Workshop are introduced in this paper. We found several clear trends in the development of ECR ion sources including: 1) intense beam production for secondary beams; 2) pulsed mode operation for beta-beam projects; 3) new applications (for trace element analysis, laser ablation of actinides, ion implanter, surface treatment...); and 4) plasma diagnostics, beam extraction and beam transport. For the point 4, presentations have been made concerning: the microwave coupling of the plasma chamber, progress in computerized simulations, the relations between the maximum energy of Bremsstrahlung and average kinetic energy of X-rays in order to understand better the heating mechanism of electrons in ECR plasmas

  11. Introductory remarks by Augusto Ancarani

    International Nuclear Information System (INIS)

    Ancarani, Augusto

    1989-01-01

    The subject proposed for the present roundtable is in the form of a twofold question. To assert that advocates and adversaries of nuclear power are listening to each other will hopefully result from what will be said. But, as far as the chance of a dialogue is concerned, one can answer in the positive from the start. Indeed a dialogue is always possible, even among deaf people, provided they are polite. This has been and still is the situation in many instances. If we consider the politics situation in a worldwide perspective, we hove to acknowledge that the mood is favorable to the dialogue on almost every possible subject. If this is true among the great powers, it will also be the case, at all the Levels, inside our democratic and articulate societies, O rice set in motion the solution of the great problems concerning peace among notions, still remain to be tackled the ones about the welfare of humankind. Such welfare rests heavily on the availability of energy; besides, energy cannot bp produced without some consequences upon the environment. This process will bi a Long and a difficult one; it will be exhausted only through confrontations, exchanges of view, dialogues, discussions - any term that you will care to choose

  12. Remarks on Chalcites malayanus (Raffles)

    NARCIS (Netherlands)

    Junge, G.C.A.

    1938-01-01

    Till now it was assumed that the Malay Peninsula, Sumatra, Java, Borneo, and Celebes are inhabited by the typical race of Chalcites malayanus. At Prof. Stresemann's request I compared the beautiful series collected by Heinrich in Celebes with the material in the Leiden Museum and it proved that the

  13. The remarkable discreteness of being

    Indian Academy of Sciences (India)

    Life is a discrete, stochastic phenomenon: for a biological organism, the time of the two most important events of its life (reproduction and death) is random and these events change the number of individuals of the species by single units. These facts can have surprising, counterintuitive consequences. I review here three ...

  14. Otofaciocervical syndrome and metachondromatosis in a girl: Presentation of a novel association and remarks on clinical variability of branchial-arch disorders.

    Science.gov (United States)

    Salinas-Torres, Victor M; Salinas-Torres, Rafael A

    2016-06-01

    Otofaciocervical syndrome (OFCS) is a rare disorder characterized by facial, ear, branchial, and musculoskeletal anomalies, along with hearing loss and mild intellectual disability. Clinically, its distinction from branchiootorenal syndrome can be difficult. To date, the coexistence of OFCS and metachondromatosis has not been reported. Here, we describe a sporadic patient with both OFCS and metachondromatosis. This novel association prompts us to do some remarks on the clinical variability of branchial-arch disorders; in fact, our observations are consistent with the highly variable expressivity of OFCS and illustrate the need of a more accurate characterization of these branchial-arch disorders. In the meantime, involvement of clavicles, scapulae and shoulders remains a distinctive feature of OFCS. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. Remarkable Diversity and Prevalence of Dagger Nematodes of the Genus Xiphinema Cobb, 1913 (Nematoda: Longidoridae) in Olives Revealed by Integrative Approaches

    Science.gov (United States)

    Archidona-Yuste, Antonio; Navas-Cortés, Juan A.; Cantalapiedra-Navarrete, Carolina; Palomares-Rius, Juan E.

    2016-01-01

    The genus Xiphinema includes a remarkable group of invertebrates of the phylum Nematoda comprising ectoparasitic animals of many wild and cultivated plants. Damage is caused by direct feeding on root cells and by vectoring nepoviruses that cause diseases on several crops. Precise identification of Xiphinema species is critical for launching appropriate control measures. We make available the first detailed information on the diversity and distribution of Xiphinema species infesting wild and cultivated olive in a wide-region in southern Spain that included 211 locations from which 453 sampling sites were analyzed. The present study identified thirty-two Xiphinema spp. in the rhizosphere of olive trees, ten species belonging to Xiphinema americanum-group, whereas twenty-two were attributed to Xiphinema non-americanum-group. These results increase our current knowledge on the biodiversity of Xiphinema species identified in olives and include the description of four new species (Xiphinema andalusiense sp. nov., Xiphinema celtiense sp. nov., Xiphinema iznajarense sp. nov., and Xiphinema mengibarense sp. nov.), and two new records for cultivate olives (X. cadavalense and X. conurum). We also found evidence of remarkable prevalence of Xiphinema spp. in olive trees, viz. 85.0% (385 out of 453 sampling sites), and they were widely distributed in both wild and cultivated olives, with 26 and 17 Xiphinema spp., respectively. Diversity indexes (Richness, Hill´s diversity, Hill´s reciprocal of D and Hill´s evenness) were significantly affected by olive type. We also developed a comparative morphological and morphometrical study together with molecular data from three nuclear ribosomal RNA genes (D2-D3 expansion segments of 28S, ITS1, and partial 18S). Molecular characterization and phylogenetic analyses allowed the delimitation and discrimination of four new species of the genus described herein and three known species. Phylogenetic analyses of Xiphinema spp. resulted in a

  16. Remarkable Diversity and Prevalence of Dagger Nematodes of the Genus Xiphinema Cobb, 1913 (Nematoda: Longidoridae) in Olives Revealed by Integrative Approaches.

    Science.gov (United States)

    Archidona-Yuste, Antonio; Navas-Cortés, Juan A; Cantalapiedra-Navarrete, Carolina; Palomares-Rius, Juan E; Castillo, Pablo

    2016-01-01

    The genus Xiphinema includes a remarkable group of invertebrates of the phylum Nematoda comprising ectoparasitic animals of many wild and cultivated plants. Damage is caused by direct feeding on root cells and by vectoring nepoviruses that cause diseases on several crops. Precise identification of Xiphinema species is critical for launching appropriate control measures. We make available the first detailed information on the diversity and distribution of Xiphinema species infesting wild and cultivated olive in a wide-region in southern Spain that included 211 locations from which 453 sampling sites were analyzed. The present study identified thirty-two Xiphinema spp. in the rhizosphere of olive trees, ten species belonging to Xiphinema americanum-group, whereas twenty-two were attributed to Xiphinema non-americanum-group. These results increase our current knowledge on the biodiversity of Xiphinema species identified in olives and include the description of four new species (Xiphinema andalusiense sp. nov., Xiphinema celtiense sp. nov., Xiphinema iznajarense sp. nov., and Xiphinema mengibarense sp. nov.), and two new records for cultivate olives (X. cadavalense and X. conurum). We also found evidence of remarkable prevalence of Xiphinema spp. in olive trees, viz. 85.0% (385 out of 453 sampling sites), and they were widely distributed in both wild and cultivated olives, with 26 and 17 Xiphinema spp., respectively. Diversity indexes (Richness, Hill´s diversity, Hill´s reciprocal of D and Hill´s evenness) were significantly affected by olive type. We also developed a comparative morphological and morphometrical study together with molecular data from three nuclear ribosomal RNA genes (D2-D3 expansion segments of 28S, ITS1, and partial 18S). Molecular characterization and phylogenetic analyses allowed the delimitation and discrimination of four new species of the genus described herein and three known species. Phylogenetic analyses of Xiphinema spp. resulted in a

  17. Sometimes, economic arguments provide better conditions for achieving energy efficiency in transport (A remarkable new market based approach on Commuter Mobility Management makes accessibility and energy efficiency go hand in hand)

    International Nuclear Information System (INIS)

    Elburg, Henk van

    2003-01-01

    Commuter Mobility Management (CMM) is broadly regarded as one of the most potential instruments to reduce the negative effects of mass commuting on the environment and energy demand. Until now, only 4% of private enterprise implemented CMM in the Netherlands. Business community turned out to be very reluctant in embracing CMM as a workable method. National employers' federations, representing more than 90% of employment in private sector, pictured CMM as a laborious and not effective instrument. Novem realised that the real issue was not so much about the practicability of the instrument, but more about the environmental and energy related arguments being used by the government. Novem took the initiative and invited the employers federations to participate in a unique project: the development of a Standard Set of CMM-incentives. In this project, environmental and energy related arguments were tactically avoided. The target scenario was to convince business community strictly with economic arguments. The project showed remarkable results. The influential employers' federations became more co-operative and accepted a 'Standard Set of incentives'. While not emphasising it, the 'hidden' positive effect on energy conservation is still substantial: 5% reduction of single occupant vehicle-trips during rush hours, each 'switcher' saving an average of 7,200 single occupant car kilometres each year. By 2010 this could nation wide result in a reduction of approximately 3PJ, about 4,3% of all energy used by private car travel in mass commuting. This explains the title: 'Sometimes, economic arguments provide better conditions for achieving energy efficiency in transport'

  18. Effects of Counselling Techniques in Rehabilitating Emotional

    African Journals Online (AJOL)

    Elizabeth Egbochuku

    given. Key words: Emotional adjustment, Adolescence, Depression, Stress,. Anxiety ... problems. Invariably, the effect of this situation is remarkably felt on the .... The facilitator explained rational emotive behaviour therapy and. Systematic ...

  19. The frailties of ‘basileia’ according to John Chrysostom: some remarks on the treatise ‘A comparison between a king and a monk’

    Directory of Open Access Journals (Sweden)

    Gilvan Ventura da Silva

    2016-01-01

    Full Text Available Living in a society under the threat of Persians and Barbarians, John Chrysostom, differently from his predecessors, like Eusebius of Cesarea, did not devise the Graeco-Roman basileia as an institution that bore any special religious meaning. As for him, the Roman Empire was just a gathering of humans governing other humans due to an election; a government that did not arise from a natural basis and did not exhibit any mystical, supernatural capacity, for such government was not geared to linger on. In his works, John Chrysostom seldom mentions the Imperium Chistianum and the emperors of his time, subjects which did not attract his attention. Truth to tell, according to the author, the basileus did not represent a Christian model that should be followed by his contemporaries. Such honor should be bestowed on the monks instead. In light of these remarks, we intend to discuss, in this article, some characteristics of the monarchy in the Late Antiquity, a time span when we witness the flourishing of the monasticism as well. In order to do that, we deal with one of John’s first works: the treatise A comparison between a king and a monk, written in Antioch, John’s homeland, in the first years of the decade of 370 A. D.

  20. Remarkable change in age-specific breast cancer incidence in the Swiss canton of Geneva and its possible relation with the use of hormone replacement therapy

    International Nuclear Information System (INIS)

    Bouchardy, Christine; Morabia, Alfredo; Verkooijen, Helena M; Fioretta, Gérald; Wespi, Yves; Schäfer, Peter

    2006-01-01

    This article aims to explain the reasons for the remarkable change in age of breast cancer occurrence in the Swiss canton of Geneva. We used population-based data from the Geneva cancer registry, which collects information on method of detection, stage and tumour characteristics since 1975. For patients diagnosed between 1997–2003, we obtained additional information on use of hormone replacement therapy from a large prospective study on breast cancer. Using generalized log linear regression analysis, we compared age-specific incidence rates with respect to period, stage, oestrogen receptor status, method of detection and use of hormone replacement therapy. In the periods 1975–1979 and 1985–1989, breast cancer risk increased with age, showing the highest incidence rates among women aged ≥ 85 years. From 1997, the age-specific incidence curve changed completely (p < 0.0001), showing an incidence peak at 60–64 years and a reduced incidence among elderly women. This incidence peak concerned mainly early stage and oestrogen positive cancers and was exclusively observed among women who ever used hormone replacement therapy, regardless whether the tumour was screen-detected or not. The increasing prevalence of hormone replacement therapy use during the 1990s could explain the important change in age-specific breast cancer incidence, not only by increasing breast cancer risk, but also by revealing breast cancer at an earlier age

  1. Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility.

    Science.gov (United States)

    Chen, Yizhen; Tuo, Jue; Huang, Huizhi; Liu, Dan; You, Xiuhua; Mai, Jialuo; Song, Jiaqi; Xie, Yanqi; Wu, Chuanbin; Hu, Haiyan

    2015-06-20

    The toxicity and irritation associated with high amounts of surfactants restrict the extensive utilization of microemulsions. To address these shortcomings, employing mixed oils to enlarge microemulsion areas therefore reducing surfactant contents is a promising strategy. However, what kinds of mixed oils are more efficient in enlarging microemulsion areas still remains unclear. In this research, we found that the chain length and degree of unsaturation of oils play a key role in enlarging microemulsion areas. The combination of moderate chain saturated oil caprylic/capric triglyceride (GTCC) with long chain unsaturated oil glycerol trioleate significantly increased the microemulsion areas. Solubility of ibuprofen in the mixed oils was unexpectedly and remarkably increased (almost 300mg/mL) compared with that (around 100mg/mL) of the single oil (GTCC), which also resulted in greatly increased solubility of ibuprofen in mixed oils-containing microemulsions. By optimizing the mixed oil formulation, the absolute amount of surfactant in drug-loaded microemulsions was reduced but increased drug oral bioavailability in rats was maintained. It could be concluded that the combined use of moderate chain oils and long chain unsaturated oils could not only acquire enlarged microemulsion areas but also enhanced drug solubility, therefore doubly reducing surfactant amount, which is extremely beneficial for developing safe microemulsions. Copyright © 2015. Published by Elsevier B.V.

  2. From fibrinolysis to the plasminogen-plasmin system and beyond: a remarkable growth of knowledge, with personal observations on the history of fibrinolysis.

    Science.gov (United States)

    Kwaan, Hau C

    2014-07-01

    Great advances have been made in our understanding of the fibrinolytic system from the initial discovery of proteolysis of fibrin by plasmin to the multifaceted and complex role of the plasminogen-plasmin (P-P) system. We now know that the P-P system is composed of several serine proteases and their inhibitors (serpins). This system is involved in many physiological functions, including embryogenesis, cell migration, and wound healing. They also play an important role in the pathogenesis of many diseases, including atherosclerosis, obesity, cancer, and even autoimmune disorders, and neuronal degeneration. Knowledge of their role in cancer enables their use as a prognostic factor. Therapeutic use of various forms of proteases derived from this system has been employed as thrombolytic agents. In addition, small molecules designed to inhibit many of the components of the P-P system are now available for clinical trial, aimed at treatment of these various disorders. The history of such remarkable development of our knowledge on fibrinolysis is reviewed in this article. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  3. Can the BMS Algorithm Decode Up to \\lfloor \\frac{d_G-g-1}{2}\\rfloor Errors? Yes, but with Some Additional Remarks

    Science.gov (United States)

    Sakata, Shojiro; Fujisawa, Masaya

    It is a well-known fact [7], [9] that the BMS algorithm with majority voting can decode up to half the Feng-Rao designed distance dFR. Since dFR is not smaller than the Goppa designed distance dG, that algorithm can correct up to \\lfloor \\frac{d_G-1}{2}\\rfloor errors. On the other hand, it has been considered to be evident that the original BMS algorithm (without voting) [1], [2] can correct up to \\lfloor \\frac{d_G-g-1}{2}\\rfloor errors similarly to the basic algorithm by Skorobogatov-Vladut. But, is it true? In this short paper, we show that it is true, although we need a few remarks and some additional procedures for determining the Groebner basis of the error locator ideal exactly. In fact, as the basic algorithm gives a set of polynomials whose zero set contains the error locators as a subset, it cannot always give the exact error locators, unless the syndrome equation is solved to find the error values in addition.

  4. Synthesis and Characterization of Novel Copper(II 2D Coordination Polymers from a Fluorinated Flexible Ligand with Remarkable Clathration Ability

    Directory of Open Access Journals (Sweden)

    Kayoko Kasai

    2011-11-01

    Full Text Available Two-dimensional (2D grid coordination polymers were prepared by the reaction of 1,4-bis(4-pyridylmethyltetrafluorobenzene (bpf with Cu(NO32 in the presence of aromatic compounds. Crystal structures of {[Cu(bpf2(NO32]·(biphenyl2}n (1, {[Cu(bpf2(NO32]·(m-C6H4(OMe22}n (2, {[Cu(bpf2(NO32]·PhtBu}n (3 and {[Cu(bpf2(NO3(H2O]NO3·(bpf0.5}n (4 were determined. The grid networks were held together by C–H···O and C–H···F hydrogen bonds via the NO3− anions and the tetrafluorophenylene rings of bpf, respectively. Biphenyl, m-dimethoxybenzene, t-butylbenzene, and bpf molecules were clathrated in cyclic cavities of the grid networks through arene-perfluoroarene interactions. These coordination networks have remarkable clathration ability for aromatic compounds.

  5. XMM-Newton and Chandra Observations of the Remarkable Dynamics of the Intracluster Medium and Radio Sources in the Clusters Abell 2061 and 3667

    Science.gov (United States)

    Sarazin, C.; Hogge, T.; Chatzikos, M.; Wik, D.; Giacintucci, S.; Clarke, T.; Wong, K.; Gitti, M.; Finoguenov, A.

    2014-07-01

    XMM-Newton and Chandra observations of remarkable dynamic structures in the X-ray gas and connected radio sources in three clusters are presented. Abell 2061 is a highly irregular, merging cluster in the Corona Borealis supercluster. X-ray observations show that there is a plume of very cool gas (˜1 keV) to the NE of the cluster, and a hot (7.6 keV) shock region just NE of the center. There is a very bright radio relic to the far SW of the cluster, and a central radio halo/relic with an extension to the NE. Comparison to SLAM simulations show that this is an offset merger of a ˜5 × 10^{13} M⊙ subcluster with a ˜2.5 × 10^{14} M⊙ cluster seen after first core passage. The plume is the cool-core gas from the subcluster, which has been ``slingshot'' to the NE of the cluster. The plume gas is now falling back into the cluster center, and shocks when it hits the central gas. The model predicts a strong shock to the SW at the location of the bright radio relic, and another shock at the NE radio extension. Time permitting, the observations of Abell 2626 and Abell 3667 will also be presented.

  6. Remarkable case of uncorrected type IC tricuspid atresia with adaptive pulmonary trunk dilatation to allow prolonged survival: Case report and CT fly-through

    Directory of Open Access Journals (Sweden)

    Zeke J. McKinney

    2017-06-01

    Full Text Available A remarkable case of a surgically uncorrected Type IC (no great artery transposition, no pulmonary stenosis tricuspid atresia surviving to adulthood is presented. This is a case of an adult female of 30 years of age with an atretic tricuspid valve, an atrial septal defect, a large ventricular septal defect, and a dilated pulmonary trunk. Surgical correction was never conducted on this heart with a significant congenital cardiac defect, and yet the individual survived into a fourth decade. Without surgical correction, survival to adulthood in tricuspid atresia is exceedingly rare. Survival depends on a high degree of ventricular shunting with limited pulmonary outflow obstruction. The resistance of this obstruction must be both low enough to maintain increased pulmonary blood flow and high enough to prevent systemic-level pressures upon the pulmonary vasculature. The unique finding of a significantly dilated pulmonary trunk is described, which presumably allowed this individual to survive to adulthood. This complex physiology is described and augmented with high-resolution images of this cardiac specimen. These were made possible by the application of a plastination process prior to obtaining high-resolution multi-slice computed tomography imaging studies. The result is a study comprised of multiplanar and three-dimensional data detailing the anatomic features of the specimen, which were then used to create reconstructions of the specimen for visualization of the anatomy. An understanding of the development and morphology of tricuspid atresia is essential for successful surgical correction in new patients with this congenital malformation. Keywords: Tricuspid atresia, Pulmonary blood flow, Pulmonary hypertension, Plastination, CT

  7. Relationships between in vivo microdamage and the remarkable regional material and strain heterogeneity of cortical bone of adult deer, elk, sheep and horse calcanei

    Science.gov (United States)

    Skedros, John G; Sybrowsky, Christian L; Anderson, Wm Erick; Chow, Frank

    2011-01-01

    Natural loading of the calcanei of deer, elk, sheep and horses produces marked regional differences in prevalent/predominant strain modes: compression in the dorsal cortex, shear in medial–lateral cortices, and tension/shear in the plantar cortex. This consistent non-uniform strain distribution is useful for investigating mechanisms that mediate the development of the remarkable regional material variations of these bones (e.g. collagen orientation, mineralization, remodeling rates and secondary osteon morphotypes, size and population density). Regional differences in strain-mode-specific microdamage prevalence and/or morphology might evoke and sustain the remodeling that produces this material heterogeneity in accordance with local strain characteristics. Adult calcanei from 11 animals of each species (deer, elk, sheep and horses) were transversely sectioned and examined using light and confocal microscopy. With light microscopy, 20 linear microcracks were identified (deer: 10; elk: six; horse: four; sheep: none), and with confocal microscopy substantially more microdamage with typically non-linear morphology was identified (deer: 45; elk: 24; horse: 15; sheep: none). No clear regional patterns of strain-mode-specific microdamage were found in the three species with microdamage. In these species, the highest overall concentrations occurred in the plantar cortex. This might reflect increased susceptibility of microdamage in habitual tension/shear. Absence of detectable microdamage in sheep calcanei may represent the (presumably) relatively greater physical activity of deer, elk and horses. Absence of differences in microdamage prevalence/morphology between dorsal, medial and lateral cortices of these bones, and the general absence of spatial patterns of strain-mode-specific microdamage, might reflect the prior emergence of non-uniform osteon-mediated adaptations that reduce deleterious concentrations of microdamage by the adult stage of bone development. PMID

  8. Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

    Science.gov (United States)

    2013-01-01

    Background ‘Encephalomyelitis disseminata’ (multiple sclerosis) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are both classified as diseases of the central nervous system by the World Health Organization. This review aims to compare the phenomenological and neuroimmune characteristics of MS with those of ME/CFS. Discussion There are remarkable phenomenological and neuroimmune overlaps between both disorders. Patients with ME/CFS and MS both experience severe levels of disabling fatigue and a worsening of symptoms following exercise and resort to energy conservation strategies in an attempt to meet the energy demands of day-to-day living. Debilitating autonomic symptoms, diminished cardiac responses to exercise, orthostatic intolerance and postural hypotension are experienced by patients with both illnesses. Both disorders show a relapsing-remitting or progressive course, while infections and psychosocial stress play a large part in worsening of fatigue symptoms. Activated immunoinflammatory, oxidative and nitrosative (O+NS) pathways and autoimmunity occur in both illnesses. The consequences of O+NS damage to self-epitopes is evidenced by the almost bewildering and almost identical array of autoantibodies formed against damaged epitopes seen in both illnesses. Mitochondrial dysfunctions, including lowered levels of ATP, decreased phosphocreatine synthesis and impaired oxidative phosphorylation, are heavily involved in the pathophysiology of both MS and ME/CFS. The findings produced by neuroimaging techniques are quite similar in both illnesses and show decreased cerebral blood flow, atrophy, gray matter reduction, white matter hyperintensities, increased cerebral lactate and choline signaling and lowered acetyl-aspartate levels. Summary This review shows that there are neuroimmune similarities between MS and ME/CFS. This further substantiates the view that ME/CFS is a neuroimmune illness and that patients with MS are immunologically primed to

  9. IRAS 15099-5856: REMARKABLE MID-INFRARED SOURCE WITH PROMINENT CRYSTALLINE SILICATE EMISSION EMBEDDED IN THE SUPERNOVA REMNANT MSH15-52

    International Nuclear Information System (INIS)

    Koo, Bon-Chul; Kim, Hyun-Jeong; Im, Myungshin; McKee, Christopher F.; Suh, Kyung-Won; Moon, Dae-Sik; Lee, Ho-Gyu; Onaka, Takashi; Burton, Michael G.; Hiramatsu, Masaaki; Bessell, Michael S.; Gaensler, B. M.; Lee, Jae-Joon; Jeong, Woong-Seob; Tatematsu, Ken'ichi; Kawabe, Ryohei; Ezawa, Hajime; Kohno, Kotaro; Wilson, Grant; Yun, Min S.

    2011-01-01

    We report new mid-infrared (MIR) observations of the remarkable object IRAS 15099-5856 using the space telescopes AKARI and Spitzer, which demonstrate the presence of prominent crystalline silicate emission in this bright source. IRAS 15099-5856 has a complex morphology with a bright central compact source (IRS1) surrounded by knots, spurs, and several extended (∼4') arc-like filaments. The source is seen only at ≥10 μm. The Spitzer mid-infrared spectrum of IRS1 shows prominent emission features from Mg-rich crystalline silicates, strong [Ne II] 12.81 μm, and several other faint ionic lines. We model the MIR spectrum as thermal emission from dust and compare with the Herbig Be star HD 100546 and the luminous blue variable R71, which show very similar MIR spectra. Molecular line observations reveal two molecular clouds around the source, but no associated dense molecular cores. We suggest that IRS1 is heated by UV radiation from the adjacent O star Muzzio 10 and that its crystalline silicates most likely originated in a mass outflow from the progenitor of the supernova remnant (SNR) MSH 15-52. IRS1, which is embedded in the SNR, could have been shielded from the SN blast wave if the progenitor was in a close binary system with Muzzio 10. If MSH 15-52 is a remnant of Type Ib/c supernova (SN Ib/c), as has been previously proposed, this would confirm the binary model for SN Ib/c. IRS1 and the associated structures may be the relics of massive star death, as shaped by the supernova explosion, the pulsar wind, and the intense ionizing radiation of the embedded O star.

  10. Some Remarks on the Translation of Proper Names in Mark of Toledo’s and Robert of Ketton’s Latin Qur’ā Translations

    Directory of Open Access Journals (Sweden)

    Cecini, Ulisse

    2014-12-01

    Full Text Available This article presents Robert of Ketton’s (1143 and Mark of Toledo’s (1210 Latin translations of proper names appearing in the Qur’ān. Proper names represent a particular sub-group of words that challenges the translator in his task as a mediator between two cultures. Proper names are in fact tied to the person or the entity to which they belong and cannot, in absolute terms, be translated without losing their characteristic of being “proper.” In the article, the names are divided in different categories and the different methods are explained, that each translator uses to render the names in the translation. Final remarks try to formulate some hypotheses in order to explain the different choices of each translator in the context of their respective Qur’ān translation.En este artículo se presentan las traducciones latinas que Robert de Ketton (1143 y Marcos de Toledo (1210 hicieron de los nombres propios que aparecen en el Corán. Los nombres propios son un grupo particular de palabras que ponen a prueba al traductor en su tarea como mediador entre dos culturas. En efecto, los nombres propios son naturalmente vinculados a la persona o la entidad a las que pertenecen y no pueden ser traducidos sin perder su característica de ser «propios». En el artículo los nombres se dividen en diferentes categorías y se exponen de forma detallada los diferentes métodos que cada traductor utiliza para expresar los nombres en Latín. En las observaciones finales se formulan algunas hipótesis para explicar las diferentes soluciones que cada traductor ha elegido en el contexto de su propia traducción del Corán.

  11. Observações sobre a libido colonizada: tentando pensar ao largo do patriarcado Remarks on the colonized libido: trying to think beyond patriarchy

    Directory of Open Access Journals (Sweden)

    Hilan Bensusan

    2004-04-01

    Full Text Available Nestas observações procuro refletir sobre algumas conseqüências da maneira como pensamos e vivemos nossos desejos. Procuro contrastar nossos desejos com a idéia de liberdade e com a maneira como pensamos a natureza. Isso me leva rapidamente a pensar na pornografia, na identidade masculina e em seguida no nosso regime de auto-estima. Desemboco então em um conjunto de temas que se relacionam com as estruturas institucionais e emocionais do patriarcado sob um regime de heterossexualidade normatizada. Tento considerar esses temas sob um ponto de vista da experiência de quem foi treinado na masculinidade e se incomoda com suas conseqüências. Procuro encontrar um modo de repensar o agenciamento de nossos desejos e encontrar caminhos para um exercício de nossas capacidades de desejo que sejam, de alguma forma, mais livres.In these remarks I attempt to think through some of the consequences of the way we conceive and live our desires. I try to contrast those desires with both our idea of freedom and the way we usually understand nature. This takes me quickly to issues such as pornography, male identity and then to how we gain and preserve our self-esteem. This, in turn, takes me to issues that are somehow linked to the institutional and emotional structures of patriarchy under a regime of heterosexuality as a norm. I try to consider these issues from the point of view of someone who was trained within the practices and thoughts of masculinity and is bothered by the consequences of such training. I endeavour to find a way to rethink the colonization of our desires so that we can find paths to an exercise of our capacities of desire that could be somehow freer.

  12. Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica, with remarks on the evolution of the integumental scale armour

    Directory of Open Access Journals (Sweden)

    W. Meyer

    2013-09-01

    Full Text Available Using immunohistochemistry, the study demonstrates the distribution of keratins (pan-keratin with CK1-8, 10, 14-16, 19; keratins CK1, 5, 6, 9, 10; hair keratins AE13, AE14 in the epidermis of the Malayan pangolin (Manis javanica. A varying reaction spectrum was observed for pan-keratin, with body region-dependent negative to very strong reaction intensities. The dorsolateral epidermis exhibited positive reactions only in its vital layers, whereas the abdominal epidermis showed strong positive reactions in the soft two outer strata. The single acidic and basic-to-neutral (cytokeratins produced clear variations compared to the pan-keratin tinging. E.g., CK1 appeared in all epidermal layers of both body regions, except for the ventral stratum corneum, whereas CK5, 6, 9, 10 were restricted to the soft ventral epidermis. Here, distinctly positive reactions were confined to the stratum granulosum, except for CK6 that appeared in the soft stratum corneum. A different staining pattern was obvious for the hair keratins, i.e., positive reactions of AE13 concentrated only in the granular layer of the dorsal epidermis. In the abdominal epidermis, remarkable tinging for AE14 was visible in the stratum basale, decreasing toward the corneal layer, but was also found in the outer root sheath cells of the hair follicles in the ventral body part. Our findings are discussed related to the evolution of the horny dorsal scales of the pangolin, which may have started from the tail root, projecting forward to the head

  13. Tandem repeats, high copy number and remarkable diel expression rhythm of form II RuBisCO in Prorocentrum donghaiense (Dinophyceae.

    Directory of Open Access Journals (Sweden)

    Xinguo Shi

    Full Text Available Gene structure and expression regulation of form II RuBisCO (rbcII in dinoflagellates are still poorly understood. Here we isolated this gene (Pdrbc and investigated its diel expression pattern in a harmful algal bloom forming dinoflagellate Prorocentrum donghaiense. We obtained cDNA sequences with triple tandem repeats of the coding unit (CU; the 5' region has the sequence of a typical dinoflagellate plastid gene, encoding an N-terminus with two transmembrane regions separated by a plastid transit peptide. The CUs (1,455 bp except 1464 bp in last CU are connected through a 63 bp spacer. Phylogenetic analysis showed that rbcII CUs within species formed monophyletic clusters, indicative of intraspecific gene duplication or purifying evolution. Using quantitative PCR (qPCR we estimated 117±40 CUs of Pdrbc in the P. donghaiense genome. Although it is commonly believed that most dinoflagellate genes lack transcriptional regulation, our RT-qPCR analysis on synchronized cultures revealed remarkable diel rhythm of Pdrbc expression, showing significant correlations of transcript abundance with the timing of the dark-to-light transition and cell cycle G2M-phase. When the cultures were shifted to continuous light, Pdrbc expression remained significantly correlated with the G2M-phase. Under continuous darkness the cell cycle was arrested at the G1 phase, and the rhythm of Pdrbc transcription disappeared. Our results suggest that dinoflagellate rbcII 1 undergoes duplication or sequence purification within species, 2 is organized in tandem arrays in most species probably to facilitate efficient translation and import of the encoded enzyme, and 3 is regulated transcriptionally in a cell cycle-dependent fashion at least in some dinoflagellates.

  14. Local Information Commission of Dampierre-en-Burly, meeting of November 25, 2011. Additional safety assessment. Collection of remarks by the members of the Commission on the report presented by the CNPE to the ASN on 15/9/2011

    International Nuclear Information System (INIS)

    De Ganay, C.

    2011-01-01

    This report first discusses the specifications of the additional nuclear safety assessment. The authors state that this procedure is limited to the robustness of installations and to some climatic events. They formulate several and questions on issues which are not sufficiently or even not at all addressed in these specifications. In a second part, they make remarks on the report made about the Dampierre nuclear power plant. These remarks address the different issues of the assessment: earthquakes, flooding, other extreme natural phenomena, loss of electricity supplies and cooling systems, severe accidents

  15. Boreal forests can have a remarkable role in reducing greenhouse gas emissions locally: Land use-related and anthropogenic greenhouse gas emissions and sinks at the municipal level

    Energy Technology Data Exchange (ETDEWEB)

    Vanhala, Pekka, E-mail: pekka.vanhala@ymparisto.fi [Finnish Environment Institute, Natural Environment Centre, P.O. Box 140, Mechelininkatu 34 a, FI-00251 Helsinki (Finland); Bergström, Irina [Finnish Environment Institute, Natural Environment Centre, P.O. Box 140, Mechelininkatu 34 a, FI-00251 Helsinki (Finland); Haaspuro, Tiina [University of Helsinki, Department of Environmental Sciences, P.O. Box 65, Viikinkaari 1, 00014 Helsinki (Finland); Kortelainen, Pirkko; Holmberg, Maria; Forsius, Martin [Finnish Environment Institute, Natural Environment Centre, P.O. Box 140, Mechelininkatu 34 a, FI-00251 Helsinki (Finland)

    2016-07-01

    Ecosystem services have become an important concept in policy-making. Carbon (C) sequestration into ecosystems is a significant ecosystem service, whereas C losses can be considered as an ecosystem disservice. Municipalities are in a position to make decisions that affect local emissions and therefore are important when considering greenhouse gas (GHG) mitigation. Integrated estimations of fluxes at a regional level help local authorities to develop land use policies for minimising GHG emissions and maximising C sinks. In this study, the Finnish national GHG accounting system is modified and applied at the municipal level by combining emissions and sinks from agricultural land, forest areas, water bodies and mires (land use-related GHG emissions) with emissions from activities such as energy production and traffic (anthropogenic GHG emissions) into the LUONNIKAS calculation tool. The study area consists of 14 municipalities within the Vanajavesi catchment area located in Southern Finland. In these municipalities, croplands, peat extraction sites, water bodies and undrained mires are emission sources, whereas forests are large carbon sinks that turn the land use-related GHG budget negative, resulting in C sequestration into the ecosystem. The annual land use-related sink in the study area was 78 t CO{sub 2} eq km{sup −2} and 2.8 t CO{sub 2} eq per capita. Annual anthropogenic GHG emissions from the area amounted to 250 t CO{sub 2} eq km{sup −2} and 9.2 t CO{sub 2} eq per capita. Since forests are a significant carbon sink and the efficiency of this sink is heavily affected by forest management practices, forest management policy is a key contributing factor for mitigating municipal GHG emissions. - Highlights: • The significance of natural landscapes in the regional C budgets is shown. • Boreal forests can be remarkable C sinks enabling net C sequestration in ecosystems. • The large area of forest may compensate for all C emissions in the municipality.

  16. Remarkable changes in the photoluminescent properties of Y2Ce2O7:Eu(3+) red phosphors through modification of the cerium oxidation states and oxygen vacancy ordering.

    Science.gov (United States)

    Raj, Athira K V; Prabhakar Rao, P; Sreena, T S; Sameera, S; James, Vineetha; Renju, U A

    2014-11-21

    A new series of red phosphors based on Eu(3+)-doped yttrium cerate [Y1.9Ce2O7:0.1Eu(3+), Y2Ce1.9O7:0.1Eu(3+) and Y2Ce2-xO7:xEu(3+) (x = 0.05, 0.10, 0.15, 0.20, 0.25 and 0.50)] was prepared via a conventional solid-state method. The influence of the substitution of Eu(3+) at the aliovalent site on the photoluminescent properties was determined by powder X-ray diffraction, FT Raman spectroscopy, X-ray photoelectron spectroscopy, transmission electron microscopy, scanning electron microscopy with energy-dispersive spectroscopy, UV-visible absorption spectroscopy, photoluminescence spectroscopy and lifetime measurements. The substitution of Eu(3+) at the Ce(4+) site induces a structural transition from a defect fluorite to a C-type structure, which increases the oxygen vacancy ordering and the distortion of the Eu(3+) environment, and decreases the formation of Ce(3+) states. In contrast, phosphors with isovalent substitution at the Y(3+) site exhibit the biphasic nature of defect fluorite and a C-type structure, thereby increasing the number of Ce(3+) oxidation states. These modifications resulted in remarkable changes in the photoluminescent properties of Y2Ce1.9O7:0.1Eu(3+) red phosphors, with emission intensities 3.8 times greater than those of the Ce0.9O2:0.1Eu(3+) and Y1.9Ce2O7:0.1Eu(3+). The photoluminescent properties of Y2Ce2-xO7:xEu(3+) were studied at different Eu(3+) concentrations under excitation with blue light. These phosphors emit intense red light due to the (5)D0-(7)F2 transition under excitation at 466 nm and no concentration quenching is observed with up to 50 mol% Eu(3+). They show increased lifetimes in the range 0.62-0.72 ms at Eu(3+) concentrations. The cation ordering linked to the oxygen vacancy ordering led to the uniform distribution of Eu(3+) ions in the lattice, thus allowing higher doping concentrations without quenching and consequently increasing the lifetime of the (5)D0 states. Our results demonstrate that significant improvements in

  17. The Remarkable History Of Hypnosis In New Orleans (Société Du Magnétisme De La Nouvelle Orléans): A Tribute to Dabney Ewin.

    Science.gov (United States)

    Tramontana, Joseph

    2016-01-01

    Dr. Dabney Ewin was a major factor in the revitalization of the New Orleans Society for Clinical Hypnosis (NOSCH) after it had been dormant for many years. This article briefly presents the fascinating history of the society as a tribute to Dr. Ewin, a remarkable physician.

  18. The Proteus effect: stem cells and their promise for medicine

    National Research Council Canada - National Science Library

    Parson, Ann B

    .... Their story is at once compelling, controversial, and remarkable. Part detective story, part medical history, The Proteus Effect recounts the events leading up to the discovery of stem cells and their incredible potential for the future of medicine...

  19. Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases

    OpenAIRE

    Murakami, Yuki; Hoshi, Masato; Imamura, Yukio; Arioka, Yuko; Yamamoto, Yasuko; Saito, Kuniaki

    2013-01-01

    Indoleamine 2,3-dioxygenase 1 (IDO1), the L-tryptophan-degrading enzyme, plays a key role in the immunomodulatory effects on several types of immune cells. Originally known for its regulatory function during pregnancy and chronic inflammation in tumorigenesis, the activity of IDO1 seems to modify the inflammatory state of infectious diseases. The pathophysiologic activity of L-tryptophan metabolites, kynurenines, is well recognized. Therefore, an understanding of the regulation of IDO1 and th...

  20. Herpetofauna of the Northwest Amazon forest in the state of Maranhão, Brazil, with remarks on the Gurupi Biological Reserve

    OpenAIRE

    Antonio de Freitas,Marco; Saldanha Vieira,Ruhan; Entiauspe-Neto,Omar; Oliveira e Sousa,Samantha; Farias,Tayse; Grazieli,Alanna; Barbosa de Moura,Geraldo

    2017-01-01

    Understanding the biodiversity of an area is the first step for establishing effective interventions for conservation, especially when it comes to herpetofauna, since 4.1% and 9.2%, respectively, of Brazilian amphibians and reptiles are endangered. The aim of this study is to identify the composition of the herpetofauna occurring in the Northwest Amazonian state of Maranhão, with a focus on the Gurupi Biological Reserve and surrounding areas. Samples were collected between May 2012 and Octobe...

  1. CuI nanoparticles as a remarkable catalyst in the synthesis of benzo[b][1,5]diazepines: an eco-friendly approach.

    Science.gov (United States)

    Ghasemzadeh, Mohammad Ali; Safaei-Ghomi, Javad

    2015-01-01

    Highly efficient CuI nanoparticles catalyzed one-pot synthesis of some benzo[b][1,5]diazepine derivatives via multi-component condensation of aromatic diamines, Meldrum's acid and isocyanides. The present approach creates a variety of benzo[b][1,5]diazepines as pharmaceutical and biologically active heterocyclic compounds in excellent yields and short reaction times. The salient features of the copper iodide nanoparticles are: easy preparation, cost-effective, high stability, low loading and reusability of the catalyst. The prepared copper iodide nanoparticles were fully characterized by XRD, EDX, FT-IR, SEM and TEM analysis.

  2. Remarkable proanthocyanidin adsorption properties of monastrell pomace cell wall material highlight its potential use as an alternative fining agent in red wine production.

    Science.gov (United States)

    Bautista-Ortín, Ana Belén; Ruiz-García, Yolanda; Marín, Fátima; Molero, Noelia; Apolinar-Valiente, Rafael; Gómez-Plaza, Encarna

    2015-01-21

    The existence of interactions between the polysaccharides of vegetal cell walls and proanthocyanins makes this cell wall material an interesting option for its use as a fining agent to reduce the level of proanthocyanins in wines. Pomace wastes from the winery are widely available and a source of cell wall material, and the identification of varieties whose pomace cell walls present high proanthocyanin binding capacity and of processing methods that could enhance their adsorption properties could be of great interest. This study compared the proanthocyanin adsorption properties of pomace cell wall material from three different grape varieties (Monastrell, Cabernet Sauvignon, and Syrah), and the results were compared with those obtained using fresh grape cell walls. Also, the effect of the vinification method has been studied. Analysis of the proanthocyanidins in the solution after reaction with the cell wall material, using phloroglucinolysis and size exclusion chromatography, provided quantitative and qualitative information on the adsorbed and nonadsorbed compounds. A highlight of this study was the observation that Monastrell pomace cell wall material showed a strong affinity for proanthocyanidins, with values similar to that obtained for fresh grapes cell walls, and a preferential binding of high molecular mass proanthocyanidins, so these pomace cell walls could be used in wines to reduce astringency. The use of maceration enzymes during vinification had little effect on the retention capacity of the pomace cell walls obtained from this vinification, although an increase in the retention of low molecular mass proanthocyanidins was observed, and this might have implications for wine sensory properties.

  3. Materials damaging and rupture - Volumes 1-2. General remarks, metallic materials. Non-metallic materials and biomaterials, assemblies and industrial problems

    International Nuclear Information System (INIS)

    Clavel, M.; Bompard, P.

    2009-01-01

    The rupture and damaging of materials and structures is almost always and unwanted events which may have catastrophic consequences. Even if the mechanical failure causes can often be analyzed using a thorough knowledge of materials behaviour, the forecasting and prevention of failures remain difficult. While the macroscopic mechanical behaviour is often the result of average effects at the structure or microstructure scale, the damage is very often the result of the combination of load peaks, of localization effects and of microstructure defects. This book, presented in two volumes, takes stock of the state-of-the-art of the knowledge gained in the understanding and modelling of rupture and damaging phenomena of materials and structure, mostly of metallic type. It gives an outline of the available knowledge for other classes of materials (ceramics, biomaterials, geo-materials..) and for different types of applications (aeronautics, nuclear industry). Finally, it examines the delicate problem, but very important in practice, of the behaviour of assemblies. Content: Vol.1 - physical mechanisms of materials damaging and rupture; rupture mechanics; cyclic plasticity and fatigue crack growth; fatigue crack propagation; environment-induced cracking; contacts and surfaces. Vol.2 - glasses and ceramics; natural environments: soils and rocks; mechanical behaviour of biological solid materials: the human bone; contribution of simulation to the understanding of rupture mechanisms; assemblies damaging and rupture; industrial cases (behaviour of PWR pressure vessel steels, and thermal and mechanical stresses in turbojet engines). (J.S.)

  4. REMARKS ON A GENERALIZATION OF A QUESTION RAISED BY PÁL ERDOS CONCERNING A GEOMETRIC INEQUALITY IN ˝ ACUTE TRIANGLES

    Directory of Open Access Journals (Sweden)

    Béla FINTA

    2017-12-01

    Full Text Available The purpose of this paper is to give a negative answer to a possible generalization of an open question raised by Pál Erd˝os, concerning an inequality in acute triangles. We prove here that from a < b < c does not follow a 2k + l 2k a < b2k + l 2k b < c2k + l 2k c in every acute triangle ABC, nor the opposite chain of inequalities, where k ∈ N, k ≥ 2, and a, b, c denotes the length of the triangles sites , while la, lb, lc denotes the length of the interior angle bisectors, as usual. We achieve this by constructing effectively two counterexamples, one for each type of inequalities

  5. Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases

    Directory of Open Access Journals (Sweden)

    Yuki Murakami

    2013-01-01

    Full Text Available Indoleamine 2,3-dioxygenase 1 (IDO1, the L-tryptophan-degrading enzyme, plays a key role in the immunomodulatory effects on several types of immune cells. Originally known for its regulatory function during pregnancy and chronic inflammation in tumorigenesis, the activity of IDO1 seems to modify the inflammatory state of infectious diseases. The pathophysiologic activity of L-tryptophan metabolites, kynurenines, is well recognized. Therefore, an understanding of the regulation of IDO1 and the subsequent biochemical reactions is essential for the design of therapeutic strategies in certain immune diseases. In this paper, current knowledge about the role of IDO1 and its metabolites during various infectious diseases is presented. Particularly, the regulation of type I interferons (IFNs production via IDO1 in virus infection is discussed. This paper offers insights into new therapeutic strategies in the modulation of viral infection and several immune-related disorders.

  6. Remarks on a Generalization of a Question Raised by Pál Erdős Concerning a Geometric Inequality in Acute Triangles II

    Directory of Open Access Journals (Sweden)

    Béla FINTA

    2018-06-01

    Full Text Available The purpose of this paper is to give a negative answer to a possible generalization of an open question raised by Pál Erd ˝os, concerning an inequality in acute triangles. We prove here that from a < b < c does not follow a 2k+1 + (la 2k+1 < b2k+1 + l 2k+1 b < c 2k+1 + l 2k+1 c in every acute triangle ABC, nor the opposite chain of inequalities, where k ∈ N, k ≥ 2, and a, b, c denotes the length of the triangles sites, while la, lb, lc denotes the length of the interior angle bisectors, as usual. We achieve this by constructing effectively two counterexamples, one for each type of inequalities.

  7. The first ice skating rink in the world (Glaciarium) and it's remarkable inventor John Gamgee; De allereerste kunstijsbaan ter wereld en de opmerkelijke uitvinder John Gamgee

    Energy Technology Data Exchange (ETDEWEB)

    Berends, E. [Grenco, Den Bosch (Netherlands)

    2005-02-15

    Some historical aspects are given of the development of the first ice skating rink (Glaciarium) that was opened in 1876 in Chelsea, London, UK. Also attention is paid to the inventor of the skating rink, professor dr. John Gamgee and some of the other inventions of this remarkable person. [Dutch] De historie van de eerste kunstijsbaan (Glaciarium) die in 1876 in Chelsea in Londen werd geopend, wordt uit de doeken gedaan. Daarnaast wordt aandacht geschonken aan de uitvinder, professor dr. John Gamgee, en worden enkele andere uitvindingen van deze opmerkelijke man belicht.

  8. Remarkably high apparent quantum yield of the overall photocatalytic H2O splitting achieved by utilizing Zn ion added Ga2O3 prepared using dilute CaCl2 solution.

    Science.gov (United States)

    Sakata, Yoshihisa; Hayashi, Takuya; Yasunaga, Ryō; Yanaga, Nobuyuki; Imamura, Hayao

    2015-08-21

    Remarkably high photocatalytic activity for the overall H2O splitting, where the activity was 32 mmol h(-1) for H2 production and 16 mmol h(-1) for O2 production under irradiation from a 450 W high-pressure Hg lamp and the apparent quantum yield (AQY) was 71% under irradiation at 254 nm, was achieved by utilizing a Rh(0.5)Cr(1.5)O3(Rh; 0.5 wt%)/Zn(3 mol%)-Ga2O3 photocatalyst when Ga2O3 was prepared using dilute CaCl2 aqueous solution having a concentration of 0.001 mol l(-1).

  9. Treatment with rhenium-188-perrhenate and iodine-131 of NIS-expressing mammary cancer in a mouse model remarkably inhibited tumor growth

    Energy Technology Data Exchange (ETDEWEB)

    Dadachova, Ekaterina [Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY 10461 (United States)]. E-mail: edadacho@aecom.yu.edu; Nguyen, Andrew [Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461 (United States); Lin, Elaine Y. [Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461 (United States); Gnatovskiy, Leo [Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461 (United States); Lu, Ping [Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY 10461 (United States); Pollard, Jeffrey W. [Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461 (United States)

    2005-10-01

    Introduction: Novel therapeutic modalities are needed for breast cancer patients in whom standard treatments are not effective. Mammary gland sodium/iodide symporter has been identified as a molecular target in breast cancers in humans and in some transgenic mouse models. We report the results of a therapy study with {sup 131}I{sup -} and {sup 188}ReO{sub 4} {sup -} of breast cancer in polyoma middle T oncoprotein (PyMT) transgenic mice endogenously expressing the Na{sup +}/I{sup -} symporter (NIS). Methods: PyMT mice (12-13 weeks old) with one palpable tumor of 0.5-0.8 cm in diameter were used. For the therapy studies, PyMT mice were (1) treated with two intraperitoneal injections of 1.5 mCi of {sup 188}ReO{sub 4} {sup -} 1 week apart, (2) pretreated for 1 week with 5 {mu}g of triiodothyronine (T3) followed by two intraperitoneal injections of 1.5 mCi of {sup 131}I{sup -} 1 week apart or (3) left untreated. The tumor and normal organ uptakes were assessed by scintigraphic imaging. The thyroid function of treated and control animals was evaluated at the completion of the study by measuring the T3/thyroxine (T4) ratio in their blood. Results: There was significant uptake of {sup 131}I{sup -} and {sup 188}ReO{sub 4} {sup -} in the primary palpable tumors as well as in nonpalpable tumors, stomachs and thyroids. The tumor uptake after the second injection was 10 times lower in comparison with the first injection. Tumor growth was significantly inhibited in both the {sup 131}I{sup -} and {sup 188}ReO{sub 4} {sup -} groups in comparison with the control group, and tumors in the {sup 188}ReO{sub 4} {sup -} group increased in size significantly less than in the {sup 131}I{sup -} group. The T3/T4 ratios were calculated to be 27 and 25 for the control group and the {sup 188}ReO{sub 4} {sup -} group, respectively; for {sup 131}I{sup -}, both the T3 and T4 levels were below detection limit, demonstrating much less effect on the thyroids of treatment with {sup 188}ReO{sub 4

  10. Treatment with rhenium-188-perrhenate and iodine-131 of NIS-expressing mammary cancer in a mouse model remarkably inhibited tumor growth

    International Nuclear Information System (INIS)

    Dadachova, Ekaterina; Nguyen, Andrew; Lin, Elaine Y.; Gnatovskiy, Leo; Lu, Ping; Pollard, Jeffrey W.

    2005-01-01

    Introduction: Novel therapeutic modalities are needed for breast cancer patients in whom standard treatments are not effective. Mammary gland sodium/iodide symporter has been identified as a molecular target in breast cancers in humans and in some transgenic mouse models. We report the results of a therapy study with 131 I - and 188 ReO 4 - of breast cancer in polyoma middle T oncoprotein (PyMT) transgenic mice endogenously expressing the Na + /I - symporter (NIS). Methods: PyMT mice (12-13 weeks old) with one palpable tumor of 0.5-0.8 cm in diameter were used. For the therapy studies, PyMT mice were (1) treated with two intraperitoneal injections of 1.5 mCi of 188 ReO 4 - 1 week apart, (2) pretreated for 1 week with 5 μg of triiodothyronine (T3) followed by two intraperitoneal injections of 1.5 mCi of 131 I - 1 week apart or (3) left untreated. The tumor and normal organ uptakes were assessed by scintigraphic imaging. The thyroid function of treated and control animals was evaluated at the completion of the study by measuring the T3/thyroxine (T4) ratio in their blood. Results: There was significant uptake of 131 I - and 188 ReO 4 - in the primary palpable tumors as well as in nonpalpable tumors, stomachs and thyroids. The tumor uptake after the second injection was 10 times lower in comparison with the first injection. Tumor growth was significantly inhibited in both the 131 I - and 188 ReO 4 - groups in comparison with the control group, and tumors in the 188 ReO 4 - group increased in size significantly less than in the 131 I - group. The T3/T4 ratios were calculated to be 27 and 25 for the control group and the 188 ReO 4 - group, respectively; for 131 I - , both the T3 and T4 levels were below detection limit, demonstrating much less effect on the thyroids of treatment with 188 ReO 4 - than with 131 I - . Conclusions: These results prove that NIS expression in breast tumors in animal models allows specific, efficient and safe treatment with a variety of

  11. Remarks on energy and development at IAEA Scientific Forum, 15 September 2009, Vienna, Austria. 12th Scientific Forum during the 53rd Session of the IAEA General Conference

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2009-01-01

    My purpose this morning is to stimulate thinking about how the world might deal effectively with two major problems, energy poverty and energy insecurity. Energy poverty is widespread and persistent. Some 2.4 billion people still rely on traditional biomass fuels, and 1.6 billion people have no access to electricity. Africa suffers particularly severely. Annual electricity use in some African countries is only 50 kilowatt-hours (kWh) per person, an average of 6 watts, less than a normal light bulb. Average annual consumption in the OECD is 8600 kWh/person, roughly 170 times higher. Energy insecurity also persists. Even affluent nations have seen major blackouts and price escalation. Insecure energy markets due to political instability and price volatility are as unwelcome to producers as they are to consumers. I have argued for some time that one way of improving the way we address these problems is to create a new global energy organization to complement, not replace, existing bodies. At the moment, many institutions deal with energy, but none with a mandate that is global, comprehensive and encompasses all energy forms

  12. Herpetofauna of the Northwest Amazon forest in the state of Maranhão, Brazil, with remarks on the Gurupi Biological Reserve

    Directory of Open Access Journals (Sweden)

    Marco Antonio de Freitas

    2017-01-01

    Full Text Available Understanding the biodiversity of an area is the first step for establishing effective interventions for conservation, especially when it comes to herpetofauna, since 4.1% and 9.2%, respectively, of Brazilian amphibians and reptiles are endangered. The aim of this study is to identify the composition of the herpetofauna occurring in the Northwest Amazonian state of Maranhão, with a focus on the Gurupi Biological Reserve and surrounding areas. Samples were collected between May 2012 and October 2013 (18 months, through pitfall traps, time constrained active search, and opportunistic encounters, and these records were supplemented by specimens collected by third parties and by bibliographic records. A total of 131 species were recorded: 31 species of amphibians and 100 species of reptiles (six testudines, 30 lizards, two amphisbaenas, 60 snakes and two alligators, including some species new to the state of Maranhão and the northeast region of Brazil. This inventory contributes to the knowledge of the herpetofauna for the Belém Endemism Center, the most devastated region of the Brazilian Amazon, and considered poorly sampled.

  13. Herpetofauna of the Northwest Amazon forest in the state of Maranhão, Brazil, with remarks on the Gurupi Biological Reserve.

    Science.gov (United States)

    de Freitas, Marco Antonio; Vieira, Ruhan Saldanha; Entiauspe-Neto, Omar Machado; Sousa, Samantha Oliveira E; Farias, Tayse; Sousa, Alanna Grazieli; de Moura, Geraldo Jorge Barbosa

    2017-01-01

    Understanding the biodiversity of an area is the first step for establishing effective interventions for conservation, especially when it comes to herpetofauna, since 4.1% and 9.2%, respectively, of Brazilian amphibians and reptiles are endangered. The aim of this study is to identify the composition of the herpetofauna occurring in the Northwest Amazonian state of Maranhão, with a focus on the Gurupi Biological Reserve and surrounding areas. Samples were collected between May 2012 and October 2013 (18 months), through pitfall traps, time constrained active search, and opportunistic encounters, and these records were supplemented by specimens collected by third parties and by bibliographic records. A total of 131 species were recorded: 31 species of amphibians and 100 species of reptiles (six testudines, 30 lizards, two amphisbaenas, 60 snakes and two alligators), including some species new to the state of Maranhão and the northeast region of Brazil. This inventory contributes to the knowledge of the herpetofauna for the Belém Endemism Center, the most devastated region of the Brazilian Amazon, and considered poorly sampled.

  14. Antioxidant activity of Artocarpus heterophyllus Lam. (Jack Fruit) leaf extracts: remarkable attenuations of hyperglycemia and hyperlipidemia in streptozotocin-diabetic rats.

    Science.gov (United States)

    Omar, Haidy S; El-Beshbishy, Hesham A; Moussa, Ziad; Taha, Kamilia F; Singab, Abdel Nasser B

    2011-04-05

    The present study examines the antioxidative, hypoglycemic, and hypolipidemic activities of Artocarpus heterophyllus (jack fruit) leaf extracts (JFEs). The 70% ethanol (JFEE), n-butanol (JFBE), water (JFWE), chloroform (JFCE), and ethyl acetate (JFEAE) extracts were obtained. Both JFEE and JFBE markedly scavenge diphenylpicrylhydrazyl radical and chelate Fe+2 in vitro. A compound was isolated from JFBE and identified using 1D and 2D 1H- and 13C-NMR. The administration of JFEE or JFBE to streptozotocin (STZ)-diabetic rats significantly reduced fasting blood glucose (FBG) from 200 to 56 and 79 mg%, respectively; elevated insulin from 10.8 to 19.5 and 15.1 µU/ml, respectively; decreased lipid peroxides from 7.3 to 5.4 and 5.9 nmol/ml, respectively; decreased %glycosylated hemoglobin A1C (%HbA1C) from 6.8 to 4.5 and 5.0%, respectively; and increased total protein content from 2.5 to 6.3 and 5.7 mg%, respectively. Triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), VLDL-C, and LDL/HDL ratio significantly declined by -37, -19, -23, -37, and -39%, respectively, in the case of JFEE; and by -31, -14, -17, -31, and -25%, respectively, in the case of JFBE; as compared to diabetic rats. HDL-C increased by +37% (JFEE) and by +11% (JFBE). Both JFEE and JFBE have shown appreciable results in decreasing FBG, lipid peroxides, %HbA1C, TC, LDL-C, and TG levels, and increasing insulin, HDL-C, and protein content. The spectrometric analysis confirmed that the flavonoid isolated from JFBE was isoquercitrin. We can conclude from this study that JFEE and JFBE exert hypoglycemic and hypolipidemic effects in STZ-diabetic rats through an antioxidative pathway that might be referred to their flavonoid contents.

  15. Some Remarks on the Slave Trade in the Heart of the Golden Horde (14th century in the Wake of C. Verlinden’s Research

    Directory of Open Access Journals (Sweden)

    Lorenzo Pubblici

    2017-09-01

    Full Text Available Objective: For decades the slave trade was very lucrative for the Italian merchants who travelled to the East. The formation of the Mongol Empire, and the economic and demographic growth occurred in Europe, have contributed to the increase of both, the demand of slaves and the supply human merchandise. Trade increased with the simultaneous increase in the number of journeys of western merchants to the East. The creation of a structured trading system on the Black Sea coast has allowed Genoa and Venice to strengthen their trade relations with the dominant centers of power in loco: the Golden Horde of the Mongols and the Mamluks of Egypt. Materials: This article is a preliminary critical mapping of a larger project I’m working on, and which aims to explore the relationship between Italian commercial immigration and the slave trade in the Venetian settlement of Tana, situated in the mouth of the Don, and representing the easternmost outpost of all Latin Trading System in the East in the 13th and 14th centuries. Based on a solid historiographical tradition and the Venetian documentary sources, I’m trying to restore the perception of a slave in the unique context of the Golden Horde, where the western urban mercantile and the eastern nomadic factors came into contact. Results and novelty of the research: While many of the conclusions of this research are still to be confirmed, a primary investigation has shown that slaves were not only the primary and most profitable resource for Italian merchants, but also the most direct and effective means to penetrate and understand an ethnic and culturally stranger context.

  16. REMARKS TO THE CURRENT DISCUSSION ABOUT BIOENERGY –BIOENERGY FOR THE PUBLIC AND/ OR FOR THE AGRICULTURAL OR RURAL AREAS ONLY ?

    Directory of Open Access Journals (Sweden)

    P. Ruckenbauer

    2008-09-01

    Full Text Available An energy system that is based on the use of renewable energy resources must be service –oriented and should be able to cover the varying energy demands. Moreover it must be flexible and cost effective by using on optimal mix of predominantly renewable energy sources. Agriculture will play an important role in the future if an optimal mix between food/feed production and energy plant production could be found. The present examples in the world to gain agricultural land for energy plants on the expenses of forests is going into the wrong direction. The cost intensive investments at present performed in Europe for biofuel and bioenergy production will certainly influence prices for crops and biomass supply. In this paper, strategies are questioned and discussed if the goals of the EU-commission to replace substantial parts of the fossile energy demands by bioenergy supply is feasible and can be realistic. As an example for a national agricultural situation, Austria, as am member of the PBBA, has elaborated a study about the timely development how much of the arable land can be utilized in the period between 2005 and 2020 for various bioenergy sources .The results demonstrate that, at the maximum , agriculture can only supply about 22 % of the total arable land for additional bioenergy as biofuel and biogas without interfering the national self food/feed supply and the protection of the sensible environment and emission situation. Finally, recent University research studies are presented about new processes to achieve a better and more efficient use of cereal and maize straw for biogas production already performed in the present 358 local biogas plants in Austria.

  17. Some remarks on the influence of temperature-variations, non-linearities, repeatability and ageing on modal-analysis for structural health monitoring of real bridges

    Directory of Open Access Journals (Sweden)

    Maas Stefan

    2015-01-01

    Full Text Available Structural Health Monitoring (SHM intends to identify damage by changes of characteristics as for instance the modal parameters. The eigenfrequencies, mode-shapes and damping-values are either directly used as damage indicators or the changes of derived parameters are analysed, such as e.g. flexibilities or updated finite element models. One common way is a continuous monitoring under environmental excitation forces, such as wind or traffic, i.e. the so-called output-only modal analysis. Alternatively, a forced measured external excitation in distinct time-intervals may be used for input-output modal analysis. Both methods are limited by the precision or the repeatability under real-life conditions at site. The paper will summarize several field tests of artificially step-by-step damaged bridges prior to their final demolishment and it will show the changes of eigenfrequencies due to induced artificial damage. Additionally, some results of a monitoring campaign of a healthy bridge in Luxembourg are presented. Reinforced concrete shows non-linear behaviour in the sense that modal parameters depend on the excitation force amplitude, i.e. higher forces lead often to lower eigenfrequencies than smaller forces. Furthermore, the temperature of real bridges is neither constant in space nor in time, while for instance the stiffness of asphalt is strongly dependant on it. Finally, ageing as such can also change a bridge’s stiffness and its modal parameters, e.g. because creep and shrinkage of concrete or ageing of elastomeric bearing pads influence their modulus of elasticity. These effects cannot be considered as damage, though they influence the measurement of modal parameters and hinder damage detection.

  18. Bioactive and biocompatible copper containing glass-ceramics with remarkable antibacterial properties and high cell viability designed for future in vivo trials.

    Science.gov (United States)

    Popescu, R A; Magyari, K; Vulpoi, A; Trandafir, D L; Licarete, E; Todea, M; Ştefan, R; Voica, C; Vodnar, D C; Simon, S; Papuc, I; Baia, L

    2016-07-19

    In the present study our interest is focused on finding the efficiency of 60SiO2·(32 - x)CaO·8P2O5·xCuO (mol%) glass-ceramics, with 0 ≤ x ≤ 4 mol%, in terms of bioactivity, biocompatibility, antibacterial properties and cell viability in order to determine the most appropriate composition for their further use in in vivo trials. The sol-gel synthesized samples show a preponderantly amorphous structure with a few crystallization centers associated with the formation of an apatite and calcium carbonate crystalline phases. The Fourier Transform Infrared (FT-IR) spectra revealed slightly modified absorption bands due to the addition of copper oxide, while the information derived from the measurements performed by transmission electron microscopy, UV-vis and electron paramagnetic resonance spectroscopy showed the presence of ions and metallic copper species. X-Ray photoelectron spectroscopic analysis indicated the presence of copper metallic species, in a reduced amount, only on the sample surface with the highest Cu content. Regarding in vitro assessment of bioactivity, the results obtained by X-ray diffraction, FT-IR spectroscopy and scanning electron microscopy, demonstrated the formation of a calcium phosphate layer on all investigated sample surfaces. The inhibitory effect of the investigated samples was more significant on the Pseudomonas aeruginosa than the Staphylococcus aureus strain, the sample with the lowest concentration of copper oxide (0.5 mol%) being also the most efficient in both bacterial cultures. This sample also exhibits a very good bactericidal activity, for the other samples it was necessary to use a higher quantity to inhibit and kill the bacterial species. The secondary structure of adsorbed albumin presents few minor changes, indicating the biocompatibility of the glass-ceramics. The cell viability assay shows a good proliferation rate on samples with 0.5 and 1.5 mol% CuO, although all glass-ceramic samples exhibited a good in vivo

  19. Antioxidant Activity of Artocarpus heterophyllus Lam. (Jack Fruit Leaf Extracts: Remarkable Attenuations of Hyperglycemia and Hyperlipidemia in Streptozotocin-Diabetic Rats

    Directory of Open Access Journals (Sweden)

    Haidy S. Omar

    2011-01-01

    Full Text Available The present study examines the antioxidative, hypoglycemic, and hypolipidemic activities of Artocarpus heterophyllus (jack fruit leaf extracts (JFEs. The 70% ethanol (JFEE, n-butanol (JFBE, water (JFWE, chloroform (JFCE, and ethyl acetate (JFEAE extracts were obtained. Both JFEE and JFBE markedly scavenge diphenylpicrylhydrazyl radical and chelate Fe+2in vitro. A compound was isolated from JFBE and identified using 1D and 2D 1H- and 13C-NMR. The administration of JFEE or JFBE to streptozotocin (STZ-diabetic rats significantly reduced fasting blood glucose (FBG from 200 to 56 and 79 mg%, respectively; elevated insulin from 10.8 to 19.5 and 15.1 μU/ml, respectively; decreased lipid peroxides from 7.3 to 5.4 and 5.91 nmol/ml, respectively; decreased %glycosylated hemoglobin A1C (%HbA1C from 6.8 to 4.5 and 5.0%, respectively; and increased total protein content from 2.5 to 6.3 and 5.7 mg%, respectively. Triglycerides (TG, total cholesterol (TC, low-density lipoprotein cholesterol (LDL-C, VLDL-C, and LDL/HDL ratio significantly declined by -37, -19, -23, -37, and -39%, respectively, in the case of JFEE; and by -31, -14, -17, -31, and -25%, respectively, in the case of JFBE; as compared to diabetic rats. HDL-C increased by +37% (JFEE and by +11% (JFBE. Both JFEE and JFBE have shown appreciable results in decreasing FBG, lipid peroxides, %HbA1C, TC, LDL-C, and TG levels, and increasing insulin, HDL-C, and protein content. The spectrometric analysis confirmed that the flavonoid isolated from JFBE was isoquercitrin. We can conclude from this study that JFEE and JFBE exert hypoglycemic and hypolipidemic effects in STZ-diabetic rats through an antioxidative pathway that might be referred to their flavonoid contents.

  20. [The end of discrimination in social security for the elderly? Some remarks on the consequences of the paradigm shift in a life course perspective on gender].

    Science.gov (United States)

    Fachinger, Uwe

    2008-10-01

    Trying to analyse the effects of the paradigm shift in the old age social security system in Germany (GRV) from a life cycle gender perspective yields light and shade - it is a conglomeration of individual- and family-specific transfers, financed by a mix of contributions and taxes, and with measures of explicit and implicit, intended and not intended ex-post and ex-ante redistribution and discrimination.The paradigm shift has increased the complexity of the system and created additional elements of gender specific discrimination as well as reduced established elements of the so called "social compensation". Furthermore, the relevance of complementary private and occupational pensions will increase absolute and relative due to the reduction of the pension level. This will raise the importance of earnings in old age especially those that are without any elements of social security compensation or without elements of recognition of activities beside employment. Overall the paradigm shift has intensified the discrimination of women in two ways and the pension privatisation has caused redistribution from the bottom to the top. In other words, there is an increase in inter- and intra-gender discrimination. Due to the changes and the emphasis of aspects of an independent old age security savings for women the norm of the "male breadwinner model" has increased. The importance of "providing one's own pension" additionally creates distribution conflicts within a partnership. Because of the necessity of constant payments over time within a private insurance and the changes of an individual income and gender-specific life cycle, conflicts may occur time and again. The dependence of life-long partnerships on each other is not reduced or abolished with the strengthening of the individualistic model of protection, but is qualitatively and quantitatively improved. Against this background, the measures of the statutory pension system which are aimed towards the situation of a

  1. Thermosensitive gating effect and selective gas adsorption in a porous coordination nanocage

    NARCIS (Netherlands)

    Zhao, D.; Yuan, D.; Krishna, R.; van Baten, J.M.; Zhou, H.C.

    2010-01-01

    A porous coordination nanocage functionalized with 24 triisopropylsilyl groups exhibits a remarkable thermosensitive gate opening phenomenon and demonstrates a molecular sieving effect at a certain temperature range, which can be used for gas separation purposes.

  2. Opening Remarks by Mr. Yury A. Sokolov [International Conference on Opportunities and Challenges for Water Cooled Reactors in the 21. Century, Vienna (Austria), 27-30 October 2009

    International Nuclear Information System (INIS)

    Sokolov, Y.A.

    2011-01-01

    replace current nuclear capacity and also to meet increased energy demand in an environmentally sound manner by building new nuclear power plants. These interests have motivated both countries with existing nuclear programmes and newcomer countries to consider the construction of new nuclear power plants in the 21st century, taking into account the desire to build capacity in terms of human resources, energy planning, regulatory capabilities and other infrastructure. Great attention is also directed toward making new plants simpler to operate, inspect, and maintain, thus increasing their safety and overall cost effectiveness. To support the future role of water cooled reactors, substantial design and development programmes are underway in a number of Member States to incorporate additional technology improvements into advanced nuclear power plants designs. A systematic approach and the experience of many years of successful operation have allowed designers to focus their design efforts and develop safer, more efficient and more reliable designs, and to optimize plant availability and cost through simpler operation and improved maintenance programs. This approach has also been successfully used for the optimization of all aspects of operation in currently operating plants, as their efficient and safe operation is a key factor in assuring that nuclear power will meet both the current and the future energy needs. It is also important to establish a forum to facilitate the exchange of information on building infrastructure, operational excellence and the sustainable deployment of advanced reactors because many of water cooled reactors will be built in countries with no previous nuclear power experience. IAEA has organized continuously international conferences or symposia on the operation and maintenance of existing nuclear power plants and on the development of advanced water cooled reactor technologies.

  3. Substrate-Triggered Formation and Remarkable Stability of the C-H-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2†

    Science.gov (United States)

    Matthews, Megan L.; Krest, Courtney M.; Barr, Eric W.; Vaillancourt, Frédéric H.; Walsh, Christopher T.; Green, Michael T.; Krebs, Carsten; Bollinger, J. Martin

    2009-01-01

    Aliphatic halogenases activate O2, cleave α-ketoglutarate (αKG) to CO2 and succinate, and form haloferryl [X-Fe(IV)=O; X = Cl, Br] complexes that cleave aliphatic C-H bonds to install halogens during the biosynthesis of natural products by non-ribosomal peptide synthetases (NRPSs). For the related αKG-dependent dioxygenases, it has been shown that reaction of the Fe(II) cofactor with O2 to form the C-H-cleaving ferryl complex is “triggered” by binding of the target substrate. In this study, we have tested for and defined structural determinants of substrate triggering (ST) in the halogenase, SyrB2, from the syringomycin E biosynthetic NRPS of Pseudomonas syringae B301D. As for other halogen ases, the substrate of SyrB2 is complex, consisting of l-Thr tethered via thioester linkage to a covalently bound phosphopantetheine (PPant) cofactor of a carrier protein, SyrB1. Without an appended amino acid, SyrB1 does not trigger formation of the chloroferryl intermediate state in SyrB2, even in the presence of free l-Thr or its analogues, but SyrB1 charged either by l-Thr or by any of several non-native amino acids does trigger the reaction by as much as 8,000-fold (for l-Thr-S-SyrB1). Triggering efficacy is sensitive to the structures of both the amino acid and the carrier protein, being diminished by 5–20-fold when the native l-Thr is replaced by another amino acid and by ∼ 40-fold when SyrB1 is replaced by a heterologous carrier protein, CytC2. The directing effect of the carrier protein and consequent tolerance for profound modifications to the target amino acid allow the chloroferryl state to be formed in the presence of substrates that perturb the ratio of its two putative coordination isomers, lack the target C-H bond (l-Ala-S-SyrB1), or contain a C-H bond of enhanced strength (l-cyclopropylglycyl-S-SyrB1). For the latter two cases, the SyrB2 chloroferryl state so formed exhibits unprecedented stability (t1/2 = 30 – 110 min at 0 °C), can be trapped in

  4. RETROSPECTIVE ANALYSIS: REPRODUCIBILITY OF INTERBLASTOMERE DIFFERENCES OF mRNA EXPRESSION IN 2-CELL STAGE MOUSE EMBRYOS IS REMARKABLY POOR DUE TO COMBINATORIAL MECHANISMS OF BLASTOMERE DIVERSIFICATION.

    Science.gov (United States)

    Casser, E; Israel, S; Schlatt, S; Nordhoff, V; Boiani, M

    2018-05-09

    What is the prevalence, reproducibility and biological significance of transcriptomic differences between sister blastomeres of the mouse 2-cell embryo? Sister 2-cell stage blastomeres are distinguishable from each other by mRNA analysis, attesting to the fact that differentiation starts mostly early in the mouse embryo; however, the interblastomere differences are poorly reproducible and invoke the combinatorial effects of known and new mechanisms of blastomere diversification. Transcriptomic datasets for single blastomeres in mice have been available for years but have never been systematically analysed together, although such an analysis may shed light onto some unclarified topics of early mammalian development. Two unknowns that remain are at which stage embryonic blastomeres start to diversify from each other and what is the molecular origin of that difference. At the earliest postzygotic stage, the 2-cell stage, opinions differ regarding the answer to these questions; one group claims that the first zygotic division yields two equal blastomeres capable of forming a full organism (totipotency) and another group claims evidence for interblastomere differences reminiscent of the prepatterning found in embryos of lower taxa. Regarding the molecular origin of interblastomere differences, there are four prevalent models which invoke 1) oocyte anisotropy, 2) sperm entry point, 3) partition errors of the transcript pool, and 4) asynchronous embryonic genome activation in the two blastomeres. Seven transcriptomic studies published between 2011 and 2017 were eligible for retrospective analysis, since both blastomeres of the mouse 2-cell embryo had been analysed individually regarding the original pair associations and since the datasets were made available in public repositories. Five of these studies, encompassing a total of 43 pairs of sister blastomeres, were selected for further analyses based on high interblastomere correlations of mRNA levels. A double cut

  5. Effects of Aglumin on the rectal bleeding following radiotherapy

    International Nuclear Information System (INIS)

    Yamashita, Michitaka; Tanaka, Motoshi; Yoshimura, Osamu; Matsubayashi, Shigeru

    1978-01-01

    Aglumin was administered to 20 cases which had rectal bleeding following radiotherapy. The results were as follows. Rectal bleeding decreased in 16 of 20 cases (80%): remarkably effective, 15%; effective, 25%; slightly effective, 40%. Bleeding time decreased in 11 cases (55%). Rumpel-Leede test gave remarkable improvement in 10 of 14 cases which had been abnormal (71.4%). Platelet increased in 18 of 20 cases (90%). Liver function test and peripheral blood findings showed no remarkable changes. No side effects such as intestinal disturbance etc were noted. In the series of symptomatic treatment for rectal disturbance resulting from radiotherapy, this drug had considerable effect of hemostasis. It was concluded that this drug is useful in combined use with other antiphlogistics, analgesic, and hematinic etc. (Ueda, J.)

  6. Some remarks on applied radiation chemistry

    International Nuclear Information System (INIS)

    Sakurada, I.

    1979-01-01

    Radiation induced polymerization and grafting are two important reactions in the processing. Numerous reports concerning these subjects have appeared in the literature. There are, however, still many problems which have been left unsolved or neglected. Several problems will be taken up in this paper and discussed on experiments carried out in Osaka Laboratory for Radiation Chemistry and Department of Polymer Chemistry of Kyoto University. (author)

  7. Generation IV international forum 2002 - remarks

    International Nuclear Information System (INIS)

    Abraham, S.

    2002-01-01

    Analyses and forecasts underscore the important role of nuclear power in energy supply in the 21st century. Important aspects in this respect are the conservation of fossil resources, the protection of the world's climate, and the continuity of supply. Present 1st and 2nd generation nuclear power plants ensure an economical and technically mature electricity supply. Advanced systems offering, e.g., higher efficiency of fuel utilization, simplified systems technology, and advanced safety characteristics, can make available additional benefits in using nuclear power. Upon an initiative of the U.S. Department of Energy (DOE), ten countries combine their efforts in developing such reactor concepts in the Generation IV International Forum (GIF). Argentina, Brazil, Canada, France, Japan, South Africa, South Korea, Switzerland, the United Kingdom, and the United States pursue the common objective in GIF to identify suitable nuclear power systems and promote their development up to the envisaged readiness for construction in 2030. Besides technical and economic questions of nuclear power generation, also other aspects must be considered with a view to the future use of nuclear power. The particularly relevant issues, such as the management of radioactive waste, the intensification of research and development, and international cooperation, have been taken up by the Bush administration at an early point in time and have been, or will be, incorporated in practical solutions, as in the case of the Yucca Mountain repository project. (orig.)

  8. Brief introductory remarks on heterogeneous photocatalysis

    Energy Technology Data Exchange (ETDEWEB)

    Serpone, Nick [Laboratory of Pure and Applied Studies in Catalysis, Environment and Materials, Department of Chemistry, Concordia University, Montreal, QU (Canada)

    1995-08-01

    Special attention is paid to heterogeneous photocatalysis, in particular to photocatalysis utilizing titania (anatase, TiO{sub 2}) since both H{sub 2}O{sub 2} and O{sub 3} absorb no sunlight, while TiO{sub 2} does absorb sunlight, though not extensively. It is also worth noting that many of the pollutants existing in water absorb little of the sunlight, either because their spectral properties do not overlap with the sun`s spectrum (AM1) or because sunlight never reaches the pollutants, particularly when these are adsorbed in sediments in rivers and lakes.

  9. Qualitative Research in Communication. Introductory Remarks

    Directory of Open Access Journals (Sweden)

    Liz Yeomans

    2016-02-01

    Full Text Available The 20th century’s epistemological turn in social sciences (Denzin & Lincoln, 1994; Punch, 2013 acknowledged the importance of qualitative research methods. The need for this turn was also pointed out by Habermas (1979, who noticed that the way data was collected in social sciences affected the analysis and data interpretation. Research gained a comprehensive character and proposed a phenomenological approach of reality (Guba & Lincoln, 1994; Willig, 2008; Lindlof & Taylor, 2011. Nowadays, we notice a “more confident community of scholars” whose earlier endeavors had “opened up the study of cultures, meanings, symbolic performances, and social practices” (Lindlof & Taylor, 2002, p. xi.

  10. The globalization of epidemiology: introductory remarks.

    Science.gov (United States)

    Pearce, Neil

    2004-10-01

    We are all living in the era of globalization, and like it or not, it is going to change the way we practice epidemiology, the kinds of questions we ask, and the methods we use to answer them. Increasingly, pubic health problems are being shifted from rich countries to poor countries and from rich to poor populations within Western countries. There is increasing interest and concern about the situation in non-Western populations on the part of Western epidemiologists, with regards to collaborative research, skills transfer, and 'volunteerism' to enable the 'benefits' of Western approaches to epidemiology to be shared by the non-Western world. However, most existing collaborations benefit Western epidemiologists rather than the countries in which the research is conducted. Even when research in non-Western populations is conducted as a genuine collaboration, it can too often 'export failure' from the West. On the other hand, non-Western epidemiologists are increasingly developing new and innovative approaches to health research that are more appropriate to the global public health issues they are addressing. These include recognition of the importance of context and the importance of diversity and local knowledge, and a problem-based approach to addressing the major public health problems using appropriate technology. These debates formed the background for a plenary session on 'International Epidemiology and International Health' at the recent International Epidemiological Association (IEA) meeting in Montreal, and the papers from this session are presented here. The development of a truly global epidemiology can not only better address the public health problems in non-Western populations, but can shed light on the current limitations of epidemiology in addressing the major public health problems in the West.

  11. Some remarks on quasi-Hermitian operators

    Energy Technology Data Exchange (ETDEWEB)

    Antoine, Jean-Pierre, E-mail: jean-pierre.antoine@uclouvain.be [Institut de Recherche en Mathématique et Physique, Université Catholique de Louvain, B-1348 Louvain-la-Neuve (Belgium); Trapani, Camillo, E-mail: camillo.trapani@unipa.it [Dipartimento di Matematica e Informatica, Università di Palermo, I-90123, Palermo (Italy)

    2014-01-15

    A quasi-Hermitian operator is an operator that is similar to its adjoint in some sense, via a metric operator, i.e., a strictly positive self-adjoint operator. Whereas those metric operators are in general assumed to be bounded, we analyze the structure generated by unbounded metric operators in a Hilbert space. Following our previous work, we introduce several generalizations of the notion of similarity between operators. Then we explore systematically the various types of quasi-Hermitian operators, bounded or not. Finally, we discuss their application in the so-called pseudo-Hermitian quantum mechanics.

  12. Remarks on the history of isospin

    International Nuclear Information System (INIS)

    Brown, L.M.

    1988-01-01

    The history of the isospin concept is reviewed from the introduction of the formalism by Heisenberg in 1932 to the isospin selection rules of Adair, Radicati, and Gell-Mann and Telegdi of the early 1950s, and the significance of the concept is assessed. 34 refs

  13. Remarks on twisted noncommutative quantum field theory

    Energy Technology Data Exchange (ETDEWEB)

    Zahn, J. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2006-04-15

    We review recent results on twisted noncommutative quantum field theory by embedding it into a general framework for the quantization of systems with a twisted symmetry. We discuss commutation relations in this setting and show that the twisted structure is so rigid that it is hard to derive any predictions, unless one gives up general principles of quantum theory. It is also shown that the twisted structure is not responsible for the presence or absence of UV/IR-mixing, as claimed in the literature. (Orig.)

  14. Remarks on Gymnetis Kerremansi, v. d. Poll

    NARCIS (Netherlands)

    Neervoort van de Poll, J.R.H.

    1889-01-01

    In volume VIII (p. 231) of the »Notes”, I have described a Cetonid from Panama, under the name of Gymnetis Kerremansi. This species belongs to the Central- American fauna and of course Mr. Bates has had to deal with it in the »Biologia Centrali-Americana”. As I had recently the pleasure of visiting

  15. Remarks - Global energy outlook and externalities

    International Nuclear Information System (INIS)

    Gray, J.E.

    1994-01-01

    The author presents a global energy outlook, for the period 1990-2010. Then, he presents some views on the subject of externalities, some regulations and proscriptions about internalization of costs are detailed. (TEC)

  16. Californium-252: a remarkable versatile radioisotope

    International Nuclear Information System (INIS)

    Osborne-Lee, I.W.; Alexander, C.W.

    1995-01-01

    A product of the nuclear age, Californium-252 ( 252 Cf) has found many applications in medicine, scientific research, industry, and nuclear science education. Californium-252 is unique as a neutron source in that it provides a highly concentrated flux and extremely reliable neutron spectrum from a very small assembly. During the past 40 years, 252 Cf has been applied with great success to cancer therapy, neutron radiography of objects ranging from flowers to entire aircraft, startup sources for nuclear reactors, fission activation for quality analysis of all commercial nuclear fuel, and many other beneficial uses, some of which are now ready for further growth. Californium-252 is produced in the High Flux Isotope Reactor (HFIR) and processed in the Radiochemical Engineering Development Center (REDC), both of which are located at the Oak Ridge National Laboratory (ORNL) in Oak Ridge, Tennessee. The REDC/HFIR facility is virtually the sole supplier of 252 Cf in the western world and is the major supplier worldwide. Extensive exploitation of this product was made possible through the 252 Cf Market Evaluation Program, sponsored by the United States Department of Energy (DOE) [then the Atomic Energy Commission (AEC) and later the Energy Research and Development Administration (ERDA)]. This program included training series, demonstration centers, seminars, and a liberal loan policy for fabricated sources. The Market Evaluation Program was instituted, in part, to determine if large-quantity production capability was required at the Savannah River Laboratory (SRL). Because of the nature of the product and the means by which it is produced, 252 Cf can be produced only in government-owned facilities. It is evident at this time that the Oak Ridge research facility can meet present and projected near-term requirements. The production, shipment, and sales history of 252 Cf from ORNL is summarized herein

  17. A remark about the mean curvature

    International Nuclear Information System (INIS)

    Zhang Weitao.

    1992-11-01

    In this paper, we give an integral identity about the mean curvature in Sobolev space H 0 1 (Ω) intersection H 2 (Ω). Suppose the mean curvature on Γ=δΩ is positive, we prove some inequalities of the positive mean curvature and propose some open problems. (author). 4 refs

  18. Some remarks on chaos in topological dynamics

    Directory of Open Access Journals (Sweden)

    Huoyung Wang

    2011-10-01

    Full Text Available Bau-Sen Du introduced a notion of chaos which is stronger than Li-Yorke sensitivity. A TDS (X, f is called chaotic if there is a positive e such that for any x and any nonempty open set V of X there is a point y in V such that the pair (x, y is proximal but not e-asymptotic. In this article, we show that a TDS (T, f is transitive but not mixing if and only if (T, f is Li-Yorke sensitive but not chaotic, where T is a tree. Moreover, we compare such chaos with other notions of chaos.

  19. Opening Remarks of the Opening Plenary

    International Nuclear Information System (INIS)

    Varjoranta, T.

    2015-01-01

    This is the twelfth international Safeguards Symposium, hosted by the IAEA. And once again it is being held in cooperation with the Institute of Nuclear Materials Management and the European Safeguards Research and Development Association. Our theme is Strategy, Implementation and People. Linking the three core processes of any business - the strategy, its implementation and the people doing the work - determines the success or failure of every organization. And the strength of the link between these three processes determines the degree to which a business is able to deliver what it wants to achieve. The IAEA is no exception. To achieve our vision, meet our obligations and fulfill the expectation of our Member States requires the careful and successful linking of strategy, implementation and people, and that is what we will all be focusing on during our deliberations this week. The primary objective of this symposium is to foster dialogue and information exchange between the IAEA and experts from Member States, the nuclear industry and the broader nuclear non-proliferation community

  20. Remarks [to the] American Vocational Association Convention.

    Science.gov (United States)

    Seltz, Larry

    The current trend toward expanded use of automation and computers in manufacturing has increased the need for a working partnership between industry and vocational education. One such partnership involves the members of the personnel development staff at Nissan Motors in Smyrna, Tennessee and local secondary and postsecondary vocational education…