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Sample records for reliever therapy smart

  1. Budesonide/formoterol maintenance plus reliever therapy

    DEFF Research Database (Denmark)

    Bisgaard, Hans; Le Roux, Pascal; Bjåmer, Ditlef

    2006-01-01

    on ICS investigated whether a novel regimen using budesonide/formoterol for maintenance and reliever therapy (Symbicort maintenance and relief therapy [SMART]) [Symbicort; AstraZeneca R&D, Lund, Sweden] could reduce exacerbations. METHODS: Patients received SMART (budesonide/formoterol 80/4.5 microg qd...... maintenance plus additional inhalations for symptom relief), budesonide/formoterol 80/4.5 microg qd for maintenance (fixed combination), or higher-dose budesonide 320 microg qd (fixed-dose budesonide). Blinded as-needed medication (terbutaline 0.4 microg) was provided in both fixed-dose groups. RESULTS: SMART...... prolonged the time to first exacerbation vs fixed-dose budesonide (p = 0.02) and fixed-dose combination (p SMART vs fixed-dose budesonide and fixed-dose combination (0.08/patient vs 0.28/patient and 0.40/patient...

  2. Inversion Therapy: Can It Relieve Back Pain?

    Science.gov (United States)

    Inversion therapy: Can it relieve back pain? Does inversion therapy relieve back pain? Is it safe? Answers from Edward R. Laskowski, M.D. Inversion therapy doesn't provide lasting relief from back ...

  3. Budesonide/formoterol maintenance and reliever therapy in primary care asthma management : effects on bronchial hyperresponsiveness and asthma control

    NARCIS (Netherlands)

    Riemersma, Roland A.; Postma, Dirkje; van der Molen, Thys

    Background: The management of asthma has changed since the introduction of budesonide/formoterol (Symbicort (R)) as both maintenance and reliever therapy (SMART). SMART and its effects on bronchial hyperresponsiveness (BHR) have not been studied in primary care. Aims: To compare the effects of SMART

  4. Budesonide/formoterol maintenance and reliever therapy versus conventional best practice

    DEFF Research Database (Denmark)

    Demoly, Pascal; Louis, Renaud; Søes-Petersen, Ulrik

    2009-01-01

    Budesonide/formoterol maintenance and reliever therapy (Symbicort SMART) reduces asthma exacerbations and symptoms versus fixed-dose regimens plus short-acting beta(2)-agonists (SABA) in double-blind trials. Information is lacking regarding its effectiveness versus conventional best practice (CBP...

  5. Smart Radiation Therapy Biomaterials.

    Science.gov (United States)

    Ngwa, Wilfred; Boateng, Francis; Kumar, Rajiv; Irvine, Darrell J; Formenti, Silvia; Ngoma, Twalib; Herskind, Carsten; Veldwijk, Marlon R; Hildenbrand, Georg Lars; Hausmann, Michael; Wenz, Frederik; Hesser, Juergen

    2017-03-01

    Radiation therapy (RT) is a crucial component of cancer care, used in the treatment of over 50% of cancer patients. Patients undergoing image guided RT or brachytherapy routinely have inert RT biomaterials implanted into their tumors. The single function of these RT biomaterials is to ensure geometric accuracy during treatment. Recent studies have proposed that the inert biomaterials could be upgraded to "smart" RT biomaterials, designed to do more than 1 function. Such smart biomaterials include next-generation fiducial markers, brachytherapy spacers, and balloon applicators, designed to respond to stimuli and perform additional desirable functions like controlled delivery of therapy-enhancing payloads directly into the tumor subvolume while minimizing normal tissue toxicities. More broadly, smart RT biomaterials may include functionalized nanoparticles that can be activated to boost RT efficacy. This work reviews the rationale for smart RT biomaterials, the state of the art in this emerging cross-disciplinary research area, challenges and opportunities for further research and development, and a purview of potential clinical applications. Applications covered include using smart RT biomaterials for boosting cancer therapy with minimal side effects, combining RT with immunotherapy or chemotherapy, reducing treatment time or health care costs, and other incipient applications. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Cost-effectiveness of budesonide/formoterol for maintenance and reliever asthma therapy in Denmark--cost-effectiveness analysis based on five randomised controlled trials

    DEFF Research Database (Denmark)

    Wickstrøm, Jannie; Dam, Nanna; Malmberg, Irena

    2009-01-01

    Budesonide/formoterol maintenance and reliever therapy (Symbicort SMART) is an effective asthma-management regime where patients use budesonide/formoterol both as maintenance treatment and as additional doses as needed to improve overall asthma control by reducing symptoms and exacerbations....... The aim of this study was to determine the cost-effectiveness of the Symbicort SMART regime in Denmark vs higher dose inhaled corticosteroid (ICS) plus reliever medication, similar dose inhaled corticosteroid/long-acting beta(2)-agonist (ICS/LABA) combination therapy plus reliever medication or higher...

  7. Health technology assessment of magnet therapy for relieving pain.

    Science.gov (United States)

    Arabloo, Jalal; Hamouzadeh, Pejman; Eftekharizadeh, Fereshteh; Mobinizadeh, Mohammadreza; Olyaeemanesh, Alireza; Nejati, Mina; Doaee, Shila

    2017-01-01

    Background: Magnet therapy has been used increasingly as a new method to alleviate pain. Magnetic products are marketed with claims of effectiveness for reducing pain of various origins. However, there are inconsistent results from a limited number of randomized controlled trials (RCTs) testing the analgesic efficacy of magnet therapy. This study aimed to evaluate the safety and effectiveness of magnet therapy on reliving various types of pain. Methods: A systematic search of two main medical databases (Cochrane Library and Ovid Medline) was conducted from 1946 to May 2014. Only English systematic reviews that compared magnet therapy with other conventional treatments in patients with local pain in terms of pain relieving measures were included. The results of the included studies were thematically synthesized. Results: Eight studies were included. Magnet therapy could be used to alleviate pain of various origins including pain in various organs, arthritis, myofascial muscle pain, lower limb muscle cramps, carpal tunnel syndrome and pelvic pain. Results showed that the effectiveness of magnetic therapy was only approved in muscle pains, but its effectiveness in other indications and its application as a complementary treatment have not been established. Conclusion: According to the results, it seems that magnet therapy could not be an effective treatment for relieving different types of pain. Our results highlighted the need for further investigations to be done in order to support any recommendations about this technology.

  8. Cost-effectiveness of budesonide/formoterol for maintenance and reliever asthma therapy in Denmark--cost-effectiveness analysis based on five randomised controlled trials

    DEFF Research Database (Denmark)

    Wickstrøm, Jannie; Dam, Nanna; Malmberg, Irena

    2009-01-01

    Budesonide/formoterol maintenance and reliever therapy (Symbicort SMART) is an effective asthma-management regime where patients use budesonide/formoterol both as maintenance treatment and as additional doses as needed to improve overall asthma control by reducing symptoms and exacerbations...

  9. Overall asthma control achieved with budesonide/formoterol maintenance and reliever therapy for patients on different treatment steps

    Directory of Open Access Journals (Sweden)

    Östlund Ollie

    2011-04-01

    Full Text Available Abstract Background Adjusting medication for uncontrolled asthma involves selecting one of several options from the same or a higher treatment step outlined in asthma guidelines. We examined the relative benefit of introducing budesonide/formoterol (BUD/FORM maintenance and reliever therapy (Symbicort SMART® Turbuhaler® in patients previously prescribed treatments from Global Initiative for Asthma (GINA Steps 2, 3 or 4. Methods This is a post hoc analysis of the results of five large clinical trials (>12000 patients comparing BUD/FORM maintenance and reliever therapy with other treatments categorised by treatment step at study entry. Both current clinical asthma control during the last week of treatment and exacerbations during the study were examined. Results At each GINA treatment step, the proportion of patients achieving target levels of current clinical control were similar or higher with BUD/FORM maintenance and reliever therapy compared with the same or a higher fixed maintenance dose of inhaled corticosteroid/long-acting β2-agonist (ICS/LABA (plus short-acting β2-agonist [SABA] as reliever, and rates of exacerbations were lower at all treatment steps in BUD/FORM maintenance and reliever therapy versus same maintenance dose ICS/LABA (P Conclusions BUD/FORM maintenance and reliever therapy may be a preferable option for patients on Steps 2 to 4 of asthma guidelines requiring a more effective treatment and, compared with other fixed dose alternatives, is most effective in the higher treatment steps.

  10. Smart Drug Delivery Systems in Cancer Therapy.

    Science.gov (United States)

    Unsoy, Gozde; Gunduz, Ufuk

    2018-02-08

    Smart nanocarriers have been designed for tissue-specific targeted drug delivery, sustained or triggered drug release and co-delivery of synergistic drug combinations to develop safer and more efficient therapeutics. Advances in drug delivery systems provide reduced side effects, longer circulation half-life and improved pharmacokinetics. Smart drug delivery systems have been achieved successfully in the case of cancer. These nanocarriers can serve as an intelligent system by considering the differences of tumor microenvironment from healthy tissue, such as low pH, low oxygen level, or high enzymatic activity of matrix metalloproteinases. The performance of anti-cancer agents used in cancer diagnosis and therapy is improved by enhanced cellular internalization of smart nanocarriers and controlled drug release. Here, we review targeting, cellular internalization; controlled drug release and toxicity of smart drug delivery systems. We are also emphasizing the stimulus responsive controlled drug release from smart nanocarriers. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  11. Nanostructured transdermal hormone replacement therapy for relieving menopausal symptoms: a confocal Raman spectroscopy study

    Directory of Open Access Journals (Sweden)

    Marco Antonio Botelho

    2014-02-01

    Full Text Available OBJECTIVE: To determine the safety and efficacy of a transdermal nanostructured formulation of progesterone (10% combined with estriol (0.1% + estradiol (0.25% for relieving postmenopausal symptoms. METHODS: A total of 66 postmenopausal Brazilian women with climacteric symptoms of natural menopause received transdermal nanostructured formulations of progesterone and estrogens in the forearm daily for 60 months to mimic the normal ovarian secretory pattern. Confocal Raman spectroscopy of hormones in skin layers was performed. Clinical parameters, serum concentrations of estradiol and follicle-stimulating hormone, blood pressure, BI-RADS classification from bilateral mammography, and symptomatic relief were compared between baseline and 60 months post-treatment. Clinicaltrials.gov: NCT02033512. RESULTS: An improvement in climacteric symptoms was reported in 92.5% of women evaluated before and after 60 months of treatment. The serum concentrations of estradiol and follicle-stimulating hormone changed significantly (p<0.05 after treatment; the values of serum follicle-stimulating hormone decreased after 60 months from 82.04±4.9 to 57.12±4.1 IU/mL. A bilateral mammography assessment of the breasts revealed normal results in all women. No adverse health-related events were attributed to this hormone replacement therapy protocol. CONCLUSION: The nanostructured formulation is safe and effective in re-establishing optimal serum levels of estradiol and follicle-stimulating hormone and relieving the symptoms of menopause. This transdermal hormone replacement therapy may alleviate climacteric symptoms in postmenopausal women.

  12. Nanostructured transdermal hormone replacement therapy for relieving menopausal symptoms: a confocal Raman spectroscopy study

    International Nuclear Information System (INIS)

    Botelho, Marco Antonio; Queiroz, Dinalva Brito; Barros, Gisele; Guerreiro, Stela; Umbelino, Sonia; Lyra, Arao; Borges, Boniek; Freitas, Allan; Almeida, Jackson Guedes; Quintans Junior, Lucindo

    2014-01-01

    Objective:to determine the safety and efficacy of a transdermal nanostructured formulation of progesterone (10%) combined with estriol (0.1%) + estradiol (0.25%) for relieving postmenopausal symptoms. Methods: a total of 66 postmenopausal Brazilian women with climacteric symptoms of natural menopause received transdermal nanostructured formulations of progesterone and estrogens in the forearm daily for 60 months to mimic the normal ovarian secretory pattern. Confocal Raman spectroscopy of hormones in skin layers was performed. Clinical parameters, serum concentrations of estradiol and follicle-stimulating hormone, blood pressure, BI-RADS classification from bilateral mammography, and symptomatic relief were compared between baseline and 60 months post-treatment. Clinicaltrials.gov: NCT02033512. Results: an improvement in climacteric symptoms was reported in 92.5% of women evaluated before and after 60 months of treatment. The serum concentrations of estradiol and follicle-stimulating hormone changed significantly (p<0.05) after treatment; the values of serum follicle-stimulating hormone decreased after 60 months from 82.04 ± 4.9 to 57.12 ± 4.1 IU/mL. A bilateral mammography assessment of the breasts revealed normal results in all women. No adverse health-related events were attributed to this hormone replacement therapy protocol. Conclusion: the nanostructured formulation is safe and effective in re-establishing optimal serum levels of estradiol and follicle-stimulating hormone and relieving the symptoms of menopause. This transdermal hormone replacement therapy may alleviate climacteric symptoms in postmenopausal women. (author)

  13. Nanostructured transdermal hormone replacement therapy for relieving menopausal symptoms: a confocal Raman spectroscopy study

    Energy Technology Data Exchange (ETDEWEB)

    Botelho, Marco Antonio; Queiroz, Dinalva Brito; Barros, Gisele; Guerreiro, Stela; Umbelino, Sonia; Lyra, Arao; Borges, Boniek; Freitas, Allan, E-mail: marcobotelho@pq.cnpq.br [Universidade Potiguar, Natal, RN (Brazil). Lab. de Nanotecnologia; Fechine, Pierre [Universidade Federal do Ceara (GQMAT/UFCE), Fortaleza, CE (Brazil). Dept. de Quimica Analitica. Grupo Avancado de Biomateriais em Quimica; Queiroz, Danilo Caldas de [Instituto Federal de Ciencia e Tecnologia (IFCT), Fortaleza, CE (Brazil). Lab. de Biotecnologia; Ruela, Ronaldo [Instituto de Biotecnologia Aplicada (INBIOS), Fortaleza, CE (Brazil); Almeida, Jackson Guedes [Universidade Federal do Vale de Sao Francisco (UNIVALE), Petrolina, PE (Brazil). Fac. de Ciencias Farmaceuticas; Quintans Junior, Lucindo [Universidade Federal de Sergipe (UFSE), Sao Cristovao, SE (Brazil). Dept. de Fisiologia

    2014-06-01

    Objective:to determine the safety and efficacy of a transdermal nanostructured formulation of progesterone (10%) combined with estriol (0.1%) + estradiol (0.25%) for relieving postmenopausal symptoms. Methods: a total of 66 postmenopausal Brazilian women with climacteric symptoms of natural menopause received transdermal nanostructured formulations of progesterone and estrogens in the forearm daily for 60 months to mimic the normal ovarian secretory pattern. Confocal Raman spectroscopy of hormones in skin layers was performed. Clinical parameters, serum concentrations of estradiol and follicle-stimulating hormone, blood pressure, BI-RADS classification from bilateral mammography, and symptomatic relief were compared between baseline and 60 months post-treatment. Clinicaltrials.gov: NCT02033512. Results: an improvement in climacteric symptoms was reported in 92.5% of women evaluated before and after 60 months of treatment. The serum concentrations of estradiol and follicle-stimulating hormone changed significantly (p<0.05) after treatment; the values of serum follicle-stimulating hormone decreased after 60 months from 82.04 ± 4.9 to 57.12 ± 4.1 IU/mL. A bilateral mammography assessment of the breasts revealed normal results in all women. No adverse health-related events were attributed to this hormone replacement therapy protocol. Conclusion: the nanostructured formulation is safe and effective in re-establishing optimal serum levels of estradiol and follicle-stimulating hormone and relieving the symptoms of menopause. This transdermal hormone replacement therapy may alleviate climacteric symptoms in postmenopausal women. (author)

  14. Budesonide/formoterol maintenance and reliever therapy in adolescent patients with asthma

    DEFF Research Database (Denmark)

    Jorup, Carin; Lythgoe, Dan; Bisgaard, Hans

    2018-01-01

    Asthma control is often suboptimal in adolescents, but few studies have evaluated asthma treatments in this population.This post hoc analysis assessed the efficacy and safety of budesonide/formoterol (BUD/FORM) maintenance and reliever therapy (MART) for treatment of persistent asthma in adolescent...... (age 12-17 years) subgroups within six randomised, double-blind trials. The primary end-point was time to first severe exacerbation. Secondary end-points included number of severe exacerbations, asthma-related symptoms, night-time awakenings, morning peak expiratory flow, forced expiratory volume in 1...... s, as-needed medication use and five-item asthma control questionnaire scores.In adolescents (n=1847), BUD/FORM MART was similar to or more effective than comparators across each of the studies in reducing the risk of a first severe exacerbation (hazard ratios (HR) BUD/FORM MART versus comparators 0...

  15. The Effectiveness of Cupping Therapy on Relieving Chronic Neck and Shoulder Pain: A Randomized Controlled Trial.

    Science.gov (United States)

    Chi, Lee-Mei; Lin, Li-Mei; Chen, Chien-Lin; Wang, Shu-Fang; Lai, Hui-Ling; Peng, Tai-Chu

    2016-01-01

    The research aimed to investigate the effectiveness of cupping therapy (CT) in changes on skin surface temperature (SST) for relieving chronic neck and shoulder pain (NSP) among community residents. A single-blind experimental design constituted of sixty subjects with self-perceived NSP. The subjects were randomly allocated to two groups. The cupping group received CT at SI 15, GB 21, and LI 15 acupuncture points, and the control group received no intervention. Pain was assessed using the SST, visual analog scale (VAS), and blood pressure (BP). The main results were SST of GB 21 acupuncture point raised from 30.6°C to 32.7°C and from 30.7°C to 30.6°C in the control group. Neck pain intensity (NPI) severity scores were reduced from 9.7 to 3.6 in the cupping group and from 9.7 to 9.5 in the control group. The SST and NPI differences between the groups were statistically significant (P < 0.001). One treatment of CT is shown to increase SST. In conjunction with the physiological effect the subjective experience of NSP is reduced in intensity. Further studies are required to improve the understanding and potential long-term effects of CT.

  16. The Effectiveness of Cupping Therapy on Relieving Chronic Neck and Shoulder Pain: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Lee-Mei Chi

    2016-01-01

    Full Text Available The research aimed to investigate the effectiveness of cupping therapy (CT in changes on skin surface temperature (SST for relieving chronic neck and shoulder pain (NSP among community residents. A single-blind experimental design constituted of sixty subjects with self-perceived NSP. The subjects were randomly allocated to two groups. The cupping group received CT at SI 15, GB 21, and LI 15 acupuncture points, and the control group received no intervention. Pain was assessed using the SST, visual analog scale (VAS, and blood pressure (BP. The main results were SST of GB 21 acupuncture point raised from 30.6°C to 32.7°C and from 30.7°C to 30.6°C in the control group. Neck pain intensity (NPI severity scores were reduced from 9.7 to 3.6 in the cupping group and from 9.7 to 9.5 in the control group. The SST and NPI differences between the groups were statistically significant (P < 0.001. One treatment of CT is shown to increase SST. In conjunction with the physiological effect the subjective experience of NSP is reduced in intensity. Further studies are required to improve the understanding and potential long-term effects of CT.

  17. Smart Mesoporous Nanomaterials for Antitumor Therapy

    Directory of Open Access Journals (Sweden)

    Marina Martínez-Carmona

    2015-11-01

    Full Text Available The use of nanomaterials for the treatment of solid tumours is receiving increasing attention by the scientific community. Among them, mesoporous silica nanoparticles (MSNs exhibit unique features that make them suitable nanocarriers to host, transport and protect drug molecules until the target is reached. It is possible to incorporate different targeting ligands to the outermost surface of MSNs to selectively drive the drugs to the tumour tissues. To prevent the premature release of the cargo entrapped in the mesopores, it is feasible to cap the pore entrances using stimuli-responsive nanogates. Therefore, upon exposure to internal (pH, enzymes, glutathione, etc. or external (temperature, light, magnetic field, etc. stimuli, the pore opening takes place and the release of the entrapped cargo occurs. These smart MSNs are capable of selectively reaching and accumulating at the target tissue and releasing the entrapped drug in a specific and controlled fashion, constituting a promising alternative to conventional chemotherapy, which is typically associated with undesired side effects. In this review, we overview the recent advances reported by the scientific community in developing MSNs for antitumor therapy. We highlight the possibility to design multifunctional nanosystems using different therapeutic approaches aimed at increasing the efficacy of the antitumor treatment.

  18. Spa therapy (balneotherapy) relieves mental stress, sleep disorder, and general health problems in sub-healthy people

    Science.gov (United States)

    Yang, Bei; Qin, Qi-zhong; Han, Ling-li; Lin, Jing; Chen, Yu

    2018-02-01

    circumferences in women of various ages under 55 years were significantly reduced in the intervention group ( P 0.05). Spa therapy (balneotherapy) relieves mental stress, sleep disorder, general health, and reduces women's waist circumferences in sub-healthy people.

  19. Case Study: The Use of Massage Therapy to Relieve Chronic Low-Back Pain.

    Science.gov (United States)

    Allen, Laura

    2016-09-01

    To study the effects of massage on chronic low-back pain in a patient with four different diagnoses: osteoarthritis, scoliosis, spinal stenosis, and degenerative disc disease. The patient's goal was to cut down on the amount of pain medication he takes. A 63-year-old man with chronic back pain received four massages across a twenty-day period. Progress was recorded using the Oswestry Low Back Pain Scale, as he self-reported on levels of pain and interference with his activities of daily living. Improvement was noted in 9 out of 10 measurements of self-reported pain and activities of daily living, with the only exception being his ability to lift heavy objects, which remained unchanged. The most dramatic differences were improvements in his ability to walk, and in the changing degrees of pain. The client also self-reported being able to decrease his pain medication and the ability to ride his bicycle for the first time in years. Massage therapy is a promising treatment for chronic low-back pain for patients who may have multiple pathologies, any one of which could be responsible for the condition. Further study is encouraged to determine the efficacy of massage therapy as a readily accessible, lower-cost alternative to more invasive therapies and as an adjunct to regular medical care, when appropriate.

  20. Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma

    DEFF Research Database (Denmark)

    O'Byrne, Paul M; Bisgaard, Hans; Godard, Philippe P

    2005-01-01

    with as-needed bud/form would provide rapid symptom relief and simultaneous adjustment in antiinflammatory therapy, thereby reducing exacerbations. In this double-blind, randomized, parallel-group study, 2,760 patients with asthma aged 4-80 years (FEV1 60-100% predicted) received either terbutaline 0.4 mg...... as SABA with bud/form 80/4.5 microg twice a day (bud/form + SABA) or bud 320 microg twice a day (bud + SABA) or bud/form 80/4.5 microg twice a day with 80/4.5 microg as-needed (bud/form maintenance + relief). Children used a once-nocte maintenance dose. Bud/form maintenance + relief prolonged time...... to first severe exacerbation (p relief also prolonged...

  1. Receptive Music Therapy Is More Effective than Interactive Music Therapy to Relieve Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Tsoi, Kelvin K F; Chan, Joyce Y C; Ng, Yiu-Ming; Lee, Mia M Y; Kwok, Timothy C Y; Wong, Samuel Y S

    2018-01-25

    Music therapy is demonstrated to be effective to relieve the agitation among people with dementia, but the comparative effectiveness of methods of music engagement for people with dementia is uncertain. To evaluate the effects on cognitive functions and behavioral symptoms between interactive and receptive music therapies for people with dementia. Prospective studies evaluating interactive and receptive music therapies were identified from the OVID databases, included MEDLINE, EMBASE, PsycINFO, and CINAHL. Supplementary search was conducted in Google Scholar. The primary outcome focused on cognitive function; the secondary outcomes were apathy, anxiety, depressive symptoms, agitation, and other behavioral problems. All outcomes were measured by the standard assessment tools. The heterogeneity of studies was examined, and the effects were pooled by meta-analysis. Quality of studies and risk of bias were assessed. Thirty-eight trials involving 1418 participants with dementia were included. The mean age ranged from 75 to 90 years, and the percentage of male participants ranged from 6% to 83%. No significant difference was found between participants receiving interactive or receptive music therapy and usual care in cognitive function; the mean difference (MD) of Mini-Mental State Examination was 0.18 [95% confidence interval (CI) -1.34 to 1.69], and -0.15 (95% CI -0.55 to 0.25), respectively. Participants with receptive music therapy had significant decrease in agitation (Cohen-Mansfield Agitation Inventory: MD = -7.99, 95% CI -5.11 to -0.87) and behavioral problems (Neuropsychiatric Inventory: MD = -3.02 95% CI -5.90 to -0.15) compared to usual care, while no significant difference was found between interactive music therapy and usual care in behavioral problems and psychiatric symptoms. This study demonstrated that receptive music therapy could reduce agitation, behavioral problems, and anxiety in older people with dementia, and appears to be more

  2. The Effectiveness of Manual Therapy for Relieving Pain, Stiffness, and Dysfunction in Knee Osteoarthritis: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Xu, Qinguang; Chen, Bei; Wang, Yueyi; Wang, Xuezong; Han, Dapeng; Ding, Daofang; Zheng, Yuxin; Cao, Yuelong; Zhan, Hongsheng; Zhou, Yao

    2017-05-01

    Knee osteoarthritis (KOA) is the most common form of arthritis, leading to pain disability in seniors and increased health care utilization. Manual therapy is one widely used physical treatment for KOA. To evaluate the effectiveness and adverse events (AEs) of manual therapy compared to other treatments for relieving pain, stiffness, and physical dysfunction in patients with KOA. A systematic review and meta-analysis of manual therapy for KOA. We searched PubMed, EMBASE, the Cochrane Library, and Chinese databases for relevant randomized controlled trials (RCTs) of manual therapy for patients with KOA from the inception to October 2015 without language restrictions. RCTs compared manual therapy to the placebo or other interventional control with an appropriate description of randomization. Two reviewers independently conducted the search results identification, data extraction, and methodological quality assessment. The methodological quality was assessed by PEDro scale. Pooled data was expressed as standard mean difference (SMD), with 95% confident intervals (CIs) in a random effects model. The meta-analysis of manual therapy for KOA on pain, stiffness, and physical function were conducted. Fourteen studies involving 841 KOA participants compared to other treatments were included. The methodological quality of most included RCTs was poor. The mean PEDro scale score was 6.6. The meta-analyses results showed that manual therapy had statistically significant effects on relieving pain (standardized mean difference, SMD = -0.61, 95% CI -0.95 to -0.28, P = 76%), stiffness (SMD = -0.58, 95% CI -0.95 to -0.21, P = 81%), improving physical function (SMD = -0.49, 95% CI -0.76 to -0.22, P = 65%), and total score (SMD = -0.56, 95% CI -0.78 to -0.35, P = 50%). But in the subgroups, manual therapy did not show significant improvements on stiffness and physical function when treatment duration was less than 4 weeks. And the long-term information for manual therapy was

  3. The role of ozone therapy in maintaining the articular function and in relieving the pain for patients with knee osteoarthritis

    Directory of Open Access Journals (Sweden)

    Camelia Ciobotaru

    2014-02-01

    Full Text Available Ozone Therapy is thought to be a non-pharmacological therapy, which makes use of oxygen and ozone, It is based on the ozone characteristics, such as the antibacterial and antimycotic, anti-inflammatory and immunomodulatory, of systemic modulation of homeostasy and of the optimization of the way the organs and systems function, but also of tissue bionourishing. Some of the beneficial effects of the ozone are: the enhancement of the oxygen supply in the tissues affected by inflammation and pain, the increase of the blood stream and the removal of the metabolic waste in the joints affected, the obstruction of the substances which maintain the inflammation and pain, an immunomodulatory action upon the whole body, the stimulation of the health improving mechanisms in the body, a mio-relaxing action and thus, a better joint mobility and a better body system functioning

  4. Doxazosin oral intake therapy to relieve stent - related urinary symptoms and pain: a prospective, randomized, controlled study

    Directory of Open Access Journals (Sweden)

    Long Zhang

    Full Text Available ABSTRACT Objective: To assess the impact of Doxazosin Oral Intake Therapy on urinary symptoms and pain in patients with indwelling ureteral stents Patients and Methods: A total of 239 patients with ureteral stone-related hydronephrosis who underwent a double-J stent insertion after ureteroscopic lithotripsy were enrolled. Patients were randomized to receive doxazosin cotrolled release 4 mg once daily for 4 weeks or matching placebo. Patients completed the brief-form Chinese version Ureteric Stent Symptom Questionnaire (USSQ and quality of life (QoL score 2 weeks and 4 weeks after stent placement and 4 weeks after stent withdrawal. The analgesic use was also recorded during the stenting period. Results: Patients in Doxazosin Oral Intake Therapy group, in the first 2 weeks and second 2 weeks with the stent in situ, expressed significant lower daytime frequency (p=0.028 and p=0.038, nocturia (p=0.021 and p=0.008 and urgency (p=0.012 and p=0.014, respectively. Similarly, flank pain score, QoL score and analgesic use were also significant less in the stenting period. There was no significant difference in scores of urinary symptoms, pain and QoL during the post-stent period between two cohorts. Conclusions: Doxazosin Oral Intake Therapy reduced stent-related urinary symptoms, pain and the negative impact on QoL.

  5. Is low-level laser therapy in relieving neck pain effective? Systematic review and meta-analysis.

    Science.gov (United States)

    Kadhim-Saleh, Amjed; Maganti, Harinad; Ghert, Michelle; Singh, Sheila; Farrokhyar, Forough

    2013-10-01

    The aim of this study is to determine the efficacy of low-level laser therapy (LLLT) in reducing acute and chronic neck pain as measured by the visual analog scale (VAS). A systematic search of nine electronic databases was conducted to identify original articles. For study selection, two reviewers independently assessed titles, abstracts, and full text for eligibility. Methodological quality was assessed using the Detsky scale. Data were analyzed using random-effects model in the presence of heterogeneity and fixed-effect model in its absence. Heterogeneity was assessed using Cochran's Q statistic and quantifying I (2). Risk ratios (RR) with 95 % confidence intervals (CI) were reported. Eight randomized controlled trials involving 443 patients met the strict inclusion criteria. Inter-rater reliability for study selection was 92.8 % (95 % CIs 80.9-100 %) and for methodological quality assessment was 83.9 % (95 % CIs 19.4-96.8 %). Five trials included patients with cervical myofascial pain syndrome (CMPS), and three trials included different patient populations. A meta-analysis of five CMPS trials revealed a mean improvement of VAS score of 10.54 with LLLT (95 % CI 0.37-20.71; Heterogeneity I (2 )= 65 %, P = 0.02). This systematic review provides inconclusive evidence because of significant between-study heterogeneity and potential risk of bias. The benefit seen in the use of LLLT, although statistically significant, does not constitute the threshold of minimally important clinical difference.

  6. Adenoviral short hairpin RNA therapy targeting phosphodiesterase 5a relieves cardiac remodeling and dysfunction following myocardial infarction

    Science.gov (United States)

    Li, Longhu; Haider, Husnain Kh.; Wang, Linlin; Lu, Gang

    2012-01-01

    We previously showed that treatment with tadalafil, a long-acting phosphodiesterase-5a (PDE5a) inhibitor, effectively prevented adverse left ventricular (LV) remodeling of the infarcted heart. We hypothesized that short-hairpin RNA (shRNA) therapy targeting PDE5a would simulate the effects of pharmacological intervention for treatment of postinfarction LV remodeling and dysfunction. Experimental model of myocardial infarction was developed in female mice by permanent ligation of left coronary artery. Immediately after that, an adenoviral vector encoding for shRNA sequence targeting PDE5a (Ad-shPDE5a) was injected intramyocardially, which specifically inhibited PDE5a in the heart. Four weeks later, Ad-shPDE5a treated mice showed significant mitigation of the left ventricle (LV) dilatation and dysfunction as indicated by smaller LV cavity and more preserved ejection fraction and fractional shortening. Infarction size and fibrosis were significantly reduced in Ad-shPDE5a-treated mice. Additionally, more salvaged cardiomyocytes, significantly reduced collagen contents, and higher blood vessel density were observed in Ad-shPDE5a-treated mice. The cytoprotective effects of Ad-shPDE5a were demonstrated in vitro in Ad-shPDE5a transfected cardiomyocytes cultured under oxygen glucose deprivation. Among downstream mediators of PDE5a signaling, cyclic GMP (cGMP) and cGMP-dependent protein kinase G (PKG) were activated with concomitant reduction in caspase-3 activity. However, no significant change in PKA and cAMP activities were observed in Ad-shPDE5a-treated hearts. Inhibition with shRNA improved cardiac remodeling and dysfunction by reducing infarction size and cardiac fibrosis and increased cGMP and PKG activity. These findings suggest that PDE5 inhibition with Ad-shPDE5a is a novel approach for treatment of myocardial infarction. PMID:22447941

  7. Development of Smart Phthalocyanine-based Photosensitizers for Photodynamic Therapy

    Science.gov (United States)

    Chow, Yun Sang

    Phthalocyanines are versatile functional dyes that have shown great potential in cancer theranostics, especially in photodynamic therapy (PDT). This research work aims to develop "smart" phthalocyanine-based photosensitizers for targeted PDT. This thesis describes the synthesis, spectroscopic characterization, photophysical properties, and in vitro photodynamic activities of several series of carefully designed phthalocyanine-based photosensitizers. Chapter 1 presents an overview of PDT, including its historical development, photophysical mechanisms, and biological mechanisms. Various classes of photosensitizers are introduced with emphasis putting on phthalocyanines, which exhibit ideal characteristics of photosensitizers for PDT. In recent years, several approaches have been used to develop photosensitizers with higher tumor selectivity and minimal skin photosensitivity after PDT. Activatable photosensitizers can provide a "turn on" mechanism to offer an additional control of the specificity of treatment. Photosensitizers can also work cooperatively with the tumor-targeting groups or anticancer drugs so as to achieve targeted or dual therapy, which can enhance the efficacy of PDT. The novel approaches mentioned above have been widely used and combined to form multi-functional photosensitizing agents. These novel concepts and development of PDT are discussed and illustrated with relevant examples at the end of this chapter. To minimize the prolonged skin photosensitivity, photosensitizers that can only be activated by tumor-associated stimuli have been developed. Due to the abnormal metabolism in tumor tissues, their surface usually exhibits a lower pH compared to that of the normal tissues. Also, the pH difference between the intracellular and the physiological environment provides a pH-activation mechanism. Chapter 2 presents the synthesis and spectroscopic characterization of a pH-responsive zinc(II) phthalocyanine tetramer, in which the phthalocyanine units

  8. Internal and External Triggering Mechanism of "Smart" Nanoparticle-Based DDSs in Targeted Tumor Therapy.

    Science.gov (United States)

    Qiana, Xian-Ling; Li, Jun; Wei, Ran; Lin, Hui; Xiong, Li-Xia

    2018-05-09

    Anticancer chemotherapeutics have a lot of problems via conventional drug delivery systems (DDSs), including non-specificity, burst release, severe side-effects, and damage to normal cells. Owing to its potential to circumventing these problems, nanotechnology has gained increasing attention in targeted tumor therapy. Chemotherapeutic drugs or genes encapsulated in nanoparticles could be used to target therapies to the tumor site in three ways: "passive", "active", and "smart" targeting. To summarize the mechanisms of various internal and external "smart" stimulating factors on the basis of findings from in vivo and in vitro studies. A thorough search of PubMed was conducted in order to identify the majority of trials, studies and novel articles related to the subject. Activated by internal triggering factors (pH, redox, enzyme, hypoxia, etc.) or external triggering factors (temperature, light of different wavelengths, ultrasound, magnetic fields, etc.), "smart" DDSs exhibit targeted delivery to the tumor site, and controlled release of chemotherapeutic drugs or genes. In this review article, we summarize and classify the internal and external triggering mechanism of "smart" nanoparticle-based DDSs in targeted tumor therapy, and the most recent research advances are illustrated for better understanding. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  9. Stimuli-Regulated Smart Polymeric Systems for Gene Therapy

    Directory of Open Access Journals (Sweden)

    Ansuja Pulickal Mathew

    2017-04-01

    Full Text Available The physiological condition of the human body is a composite of different environments, each with its own parameters that may differ under normal, as well as diseased conditions. These environmental conditions include factors, such as pH, temperature and enzymes that are specific to a type of cell, tissue or organ or a pathological state, such as inflammation, cancer or infection. These conditions can act as specific triggers or stimuli for the efficient release of therapeutics at their destination by overcoming many physiological and biological barriers. The efficacy of conventional treatment modalities can be enhanced, side effects decreased and patient compliance improved by using stimuli-responsive material that respond to these triggers at the target site. These stimuli or triggers can be physical, chemical or biological and can be internal or external in nature. Many smart/intelligent stimuli-responsive therapeutic gene carriers have been developed that can respond to either internal stimuli, which may be normally present, overexpressed or present in decreased levels, owing to a disease, or to stimuli that are applied externally, such as magnetic fields. This review focuses on the effects of various internal stimuli, such as temperature, pH, redox potential, enzymes, osmotic activity and other biomolecules that are present in the body, on modulating gene expression by using stimuli-regulated smart polymeric carriers.

  10. Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy syndrome

    Directory of Open Access Journals (Sweden)

    Ramnath Santosh Ramanathan

    2016-01-01

    Full Text Available Stroke-like migraine attacks after radiation therapy (SMART syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which was treated with radiation in 1987. Her initial brain MRI (magnetic resonance imaging revealed cortical enhancement in the right temporo-parieto-occipital region. She improved spontaneously in 2 weeks and follow-up scan at 4 weeks revealed no residual enhancement or encephalomalacia. She presented 6 weeks later with aphasia. Her MRI brain revealed similar contrast-enhancing cortical lesion but on the left side. Repeat CSF studies was again negative other than elevated protein. She was treated conservatively and recovered completely within a week. Before diagnosing SMART syndrome, it is important to rule out tumor recurrence, encephalitis, posterior reversible encephalopathy syndrome (PRES and stroke. Typically the condition is self-limiting, and gradually resolves.

  11. Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome.

    Science.gov (United States)

    Ramanathan, Ramnath Santosh; Sreedher, Gayathri; Malhotra, Konark; Guduru, Zain; Agarwal, Deeksha; Flaherty, Mary; Leichliter, Timothy; Rana, Sandeep

    2016-01-01

    Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which was treated with radiation in 1987. Her initial brain MRI (magnetic resonance imaging) revealed cortical enhancement in the right temporo-parieto-occipital region. She improved spontaneously in 2 weeks and follow-up scan at 4 weeks revealed no residual enhancement or encephalomalacia. She presented 6 weeks later with aphasia. Her MRI brain revealed similar contrast-enhancing cortical lesion but on the left side. Repeat CSF studies was again negative other than elevated protein. She was treated conservatively and recovered completely within a week. Before diagnosing SMART syndrome, it is important to rule out tumor recurrence, encephalitis, posterior reversible encephalopathy syndrome (PRES) and stroke. Typically the condition is self-limiting, and gradually resolves.

  12. Smart sensors and virtual physiology human approach as a basis of personalized therapies in diabetes mellitus.

    Science.gov (United States)

    Fernández Peruchena, Carlos M; Prado-Velasco, Manuel

    2010-01-01

    Diabetes mellitus (DM) has a growing incidence and prevalence in modern societies, pushed by the aging and change of life styles. Despite the huge resources dedicated to improve their quality of life, mortality and morbidity rates, these are still very poor. In this work, DM pathology is revised from clinical and metabolic points of view, as well as mathematical models related to DM, with the aim of justifying an evolution of DM therapies towards the correction of the physiological metabolic loops involved. We analyze the reliability of mathematical models, under the perspective of virtual physiological human (VPH) initiatives, for generating and integrating customized knowledge about patients, which is needed for that evolution. Wearable smart sensors play a key role in this frame, as they provide patient's information to the models.A telehealthcare computational architecture based on distributed smart sensors (first processing layer) and personalized physiological mathematical models integrated in Human Physiological Images (HPI) computational components (second processing layer), is presented. This technology was designed for a renal disease telehealthcare in earlier works and promotes crossroads between smart sensors and the VPH initiative. We suggest that it is able to support a truly personalized, preventive, and predictive healthcare model for the delivery of evolved DM therapies.

  13. Synchronized moving aperture radiation therapy (SMART): improvement of breathing pattern reproducibility using respiratory coaching

    International Nuclear Information System (INIS)

    Neicu, Toni; Berbeco, Ross; Wolfgang, John; Jiang, Steve B

    2006-01-01

    Recently, at Massachusetts General Hospital (MGH) we proposed a new treatment technique called synchronized moving aperture radiation therapy (SMART) to account for tumour motion during radiotherapy. The basic idea of SMART is to synchronize the moving radiation beam aperture formed by a dynamic multileaf collimator with the tumour motion induced by respiration. The two key requirements for being able to successfully use SMART in clinical practice are the precise and fast detection of tumour position during the simulation/treatment and the good reproducibility of the tumour motion pattern. To fulfil the first requirement, an integrated radiotherapy imaging system is currently being developed at MGH. The results of a previous study show that breath coaching techniques are required to make SMART an efficient technique in general. In this study, we investigate volunteer and patient respiratory coaching using a commercial respiratory gating system as a respiration coaching tool. Five healthy volunteers, observed during six sessions, and 33 lung cancer patients, observed during one session when undergoing 4D CT scans, were investigated with audio and visual promptings, with free breathing as a control. For all five volunteers, breath coaching was well tolerated and the intra- and inter-session reproducibility of the breathing pattern was greatly improved. Out of 33 patients, six exhibited a regular breathing pattern and needed no coaching, four could not be coached at all due to the patient's medical condition or had difficulty following the instructions, 13 could only be coached with audio instructions and 10 could follow the instructions of and benefit from audio-video coaching. We found that, for all volunteers and for those patients who could be properly coached, breath coaching improves the duty cycle of SMART treatment. However, about half of the patients could not follow both audio and video instructions simultaneously, suggesting that the current coaching

  14. Synchronized moving aperture radiation therapy (SMART): improvement of breathing pattern reproducibility using respiratory coaching

    Energy Technology Data Exchange (ETDEWEB)

    Neicu, Toni; Berbeco, Ross; Wolfgang, John; Jiang, Steve B [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States)

    2006-02-07

    Recently, at Massachusetts General Hospital (MGH) we proposed a new treatment technique called synchronized moving aperture radiation therapy (SMART) to account for tumour motion during radiotherapy. The basic idea of SMART is to synchronize the moving radiation beam aperture formed by a dynamic multileaf collimator with the tumour motion induced by respiration. The two key requirements for being able to successfully use SMART in clinical practice are the precise and fast detection of tumour position during the simulation/treatment and the good reproducibility of the tumour motion pattern. To fulfil the first requirement, an integrated radiotherapy imaging system is currently being developed at MGH. The results of a previous study show that breath coaching techniques are required to make SMART an efficient technique in general. In this study, we investigate volunteer and patient respiratory coaching using a commercial respiratory gating system as a respiration coaching tool. Five healthy volunteers, observed during six sessions, and 33 lung cancer patients, observed during one session when undergoing 4D CT scans, were investigated with audio and visual promptings, with free breathing as a control. For all five volunteers, breath coaching was well tolerated and the intra- and inter-session reproducibility of the breathing pattern was greatly improved. Out of 33 patients, six exhibited a regular breathing pattern and needed no coaching, four could not be coached at all due to the patient's medical condition or had difficulty following the instructions, 13 could only be coached with audio instructions and 10 could follow the instructions of and benefit from audio-video coaching. We found that, for all volunteers and for those patients who could be properly coached, breath coaching improves the duty cycle of SMART treatment. However, about half of the patients could not follow both audio and video instructions simultaneously, suggesting that the current coaching

  15. Celecoxib-Induced Self-Assembly of Smart Albumin-Doxorubicin Conjugate for Enhanced Cancer Therapy.

    Science.gov (United States)

    Shi, Leilei; Xu, Li; Wu, Chenwei; Xue, Bai; Jin, Xin; Yang, Jiapei; Zhu, Xinyuan

    2018-03-14

    Recent years have witnessed the great contributions that drug combination therapy has made for enhanced cancer therapy. However, because of the complicated pharmacokinetics of combined drug formulations, the majority of combination strategies show severe adverse effects at high dosage and poor biodistribution in vivo. To overcome these deficiencies and achieve enhanced cancer therapy, we put forward a method to construct a smart albumin-based nanoplatform, denoted as K237-HSA-DC, for codelivery of cyclooxygenase-2 (COX-2) inhibitor (celecoxib) and chemotherapeutic agent (doxorubicin, DOX). Both in vitro and in vivo studies indicate that K237-HSA-DC exhibits the best therapeutic efficacy on tumor cells compared with all the other formulations. Moreover, K237-HSA-DC shows fewer side effects on normal organs in contrast to other formulations. To understand the reasons behind the improved drug efficacy in depth, we performed a cell metabonomics-based mechanism study and found that celecoxib could enhance the inhibitory effect of DOX on the transport of glucose into cells and then lead to subsequent significant energy metabolism inhibition. Considering the above-mentioned advantages of K237-HSA-DC, we believe the smart albumin-based nanoplatform can serve as a promising drug delivery system for enhanced cancer therapy.

  16. Synchronized moving aperture radiation therapy (SMART): average tumour trajectory for lung patients

    International Nuclear Information System (INIS)

    Neicu, Toni; Shirato, Hiroki; Seppenwoolde, Yvette; Jiang, Steve B

    2003-01-01

    Synchronized moving aperture radiation therapy (SMART) is a new technique for treating mobile tumours under development at Massachusetts General Hospital (MGH). The basic idea of SMART is to synchronize the moving radiation beam aperture formed by a dynamic multileaf collimator (DMLC) with the tumour motion induced by respiration. SMART is based on the concept of the average tumour trajectory (ATT) exhibited by a tumour during respiration. During the treatment simulation stage, tumour motion is measured and the ATT is derived. Then, the original IMRT MLC leaf sequence is modified using the ATT to compensate for tumour motion. During treatment, the tumour motion is monitored. The treatment starts when leaf motion and tumour motion are synchronized at a specific breathing phase. The treatment will halt when the tumour drifts away from the ATT and will resume when the synchronization between tumour motion and radiation beam is re-established. In this paper, we present a method to derive the ATT from measured tumour trajectory data. We also investigate the validity of the ATT concept for lung tumours during normal breathing. The lung tumour trajectory data were acquired during actual radiotherapy sessions using a real-time tumour-tracking system. SMART treatment is simulated by assuming that the radiation beam follows the derived ATT and the tumour follows the measured trajectory. In simulation, the treatment starts at exhale phase. The duty cycle of SMART delivery was calculated for various treatment times and gating thresholds, as well as for various exhale phases where the treatment begins. The simulation results show that in the case of free breathing, for 4 out of 11 lung datasets with tumour motion greater than 1 cm from peak to peak, the error in tumour tracking can be controlled to within a couple of millimetres while maintaining a reasonable delivery efficiency. That is to say, without any breath coaching/control, the ATT is a valid concept for some lung

  17. SMART Syndrome: Case report of a rare complication after cerebral radiation therapy

    International Nuclear Information System (INIS)

    Truntzer, P.; Salze, P.; Monjour, A.; Gaultier, C.; Ahle, G.; Guillerme, F.; Boutenbat, G.; Atlani, D.; Stilhart, B

    2012-01-01

    The authors report a 71-year-old woman case who developed, 7 years after a cerebral radiation therapy for a parieto-occipital glioblastoma, a stroke-like migraine attacks after radiotherapy syndrome (SMART syndrome), a rare complication characterized by reversible neurologic deficits with migraine described after cerebral irradiation. Transient gyri-form reversible enhancement is found on MRI during crises. This case report allows discussing the clinical, iconographic presentation and the clinical outcome of this syndrome at the light of the literature publication. (authors)

  18. Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) for veterans with traumatic brain injury: pilot randomized controlled trial.

    Science.gov (United States)

    Twamley, Elizabeth W; Jak, Amy J; Delis, Dean C; Bondi, Mark W; Lohr, James B

    2014-01-01

    Traumatic brain injury (TBI) can result in cognitive impairments and persistent postconcussive symptoms that limit functional recovery, including return to work. We evaluated a 12 wk compensatory cognitive training intervention (Cognitive Symptom Management and Rehabilitation Therapy [CogSMART]) in the context of supported employment for Veterans with mild to moderate TBI. Participants were randomly assigned to receive 12 wk of supported employment plus CogSMART or enhanced supported employment that controlled for therapist attention (control). CogSMART sessions were delivered by the employment specialist and included psychoeducation regarding TBI; strategies to improve sleep, fatigue, headaches, and tension; and compensatory cognitive strategies in the domains of prospective memory, attention, learning and memory, and executive functioning. Compared with controls, those assigned to supported employment plus CogSMART demonstrated significant reductions in postconcussive symptoms (Cohen d = 0.97) and improvements in prospective memory functioning (Cohen d = 0.72). Effect sizes favoring CogSMART for posttraumatic stress disorder symptom severity, depressive symptom severity, and attainment of competitive work within 14 wk were in the small to medium range (Cohen d = 0.35-0.49). Those who received CogSMART rated the intervention highly. Results suggest that adding CogSMART to supported employment may improve postconcussive symptoms and prospective memory. These effects, as well as smaller effects on psychiatric symptoms and ability to return to work, warrant replication in a larger trial.

  19. Highly Selective Photothermal Therapy by a Phenoxylated-Dextran-Functionalized Smart Carbon Nanotube Platform.

    Science.gov (United States)

    Han, Seungmin; Kwon, Taeyun; Um, Jo-Eun; Haam, Seungjoo; Kim, Woo-Jae

    2016-05-01

    Near-infrared (NIR) photothermal therapy using biocompatible single-walled carbon nanotubes (SWNTs) is advantageous because as-produced SWNTs, without additional size control, both efficiently absorb NIR light and demonstrate high photothermal conversion efficiency. In addition, covalent attachment of receptor molecules to SWNTs can be used to specifically target infected cells. However, this technique interrupts SWNT optical properties and inevitably lowers photothermal conversion efficiency and thus remains major hurdle for SWNT applications. This paper presents a smart-targeting photothermal therapy platform for inflammatory disease using newly developed phenoxylated-dextran-functionalized SWNTs. Phenoxylated dextran is biocompatible and efficiently suspends SWNTs by noncovalent π-π stacking, thereby minimizing SWNT bundle formations and maintaining original SWNT optical properties. Furthermore, it selectively targets inflammatory macrophages by scavenger-receptor binding without any additional receptor molecules; therefore, its preparation is a simple one-step process. Herein, it is experimentally demonstrated that phenoxylated dextran-SWNTs (pD-SWNTs) are also biocompatible, selectively penetrate inflammatory macrophages over normal cells, and exhibit high photothermal conversion efficiency. Consequently, NIR laser-triggered macrophage treatment can be achieved with high accuracy by pD-SWNT without damaging receptor-free cells. These smart targeting materials can be a novel photothermal agent candidate for inflammatory disease. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Fast and robust online adaptive planning in stereotactic MR-guided adaptive radiation therapy (SMART) for pancreatic cancer.

    Science.gov (United States)

    Bohoudi, O; Bruynzeel, A M E; Senan, S; Cuijpers, J P; Slotman, B J; Lagerwaard, F J; Palacios, M A

    2017-12-01

    To implement a robust and fast stereotactic MR-guided adaptive radiation therapy (SMART) online strategy in locally advanced pancreatic cancer (LAPC). SMART strategy for plan adaptation was implemented with the MRIdian system (ViewRay Inc.). At each fraction, OAR (re-)contouring is done within a distance of 3cm from the PTV surface. Online plan re-optimization is based on robust prediction of OAR dose and optimization objectives, obtained by building an artificial neural network (ANN). Proposed limited re-contouring strategy for plan adaptation (SMART 3CM ) is evaluated by comparing 50 previously delivered fractions against a standard (re-)planning method using full-scale OAR (re-)contouring (FULLOAR). Plan quality was assessed using PTV coverage (V 95% , D mean , D 1cc ) and institutional OAR constraints (e.g. V 33Gy ). SMART 3CM required a significant lower number of optimizations than FULLOAR (4 vs 18 on average) to generate a plan meeting all objectives and institutional OAR constraints. PTV coverage with both strategies was identical (mean V 95% =89%). Adaptive plans with SMART 3CM exhibited significant lower intermediate and high doses to all OARs than FULLOAR, which also failed in 36% of the cases to adhere to the V 33Gy dose constraint. SMART 3CM approach for LAPC allows good OAR sparing and adequate target coverage while requiring only limited online (re-)contouring from clinicians. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Synchronized moving aperture radiation therapy (SMART): superimposing tumor motion on IMRT MLC leaf sequences under realistic delivery conditions

    International Nuclear Information System (INIS)

    Xu Jun; Papanikolaou, Nikos; Shi Chengyu; Jiang, Steve B

    2009-01-01

    Synchronized moving aperture radiation therapy (SMART) has been proposed to account for tumor motions during radiotherapy in prior work. The basic idea of SMART is to synchronize the moving radiation beam aperture formed by a dynamic multileaf collimator (DMLC) with the tumor motion induced by respiration. In this paper, a two-dimensional (2D) superimposing leaf sequencing method is presented for SMART. A leaf sequence optimization strategy was generated to assure the SMART delivery under realistic delivery conditions. The study of delivery performance using the Varian LINAC and the Millennium DMLC showed that clinical factors such as collimator angle, dose rate, initial phase and machine tolerance affect the delivery accuracy and efficiency. An in-house leaf sequencing software was developed to implement the 2D superimposing leaf sequencing method and optimize the motion-corrected leaf sequence under realistic clinical conditions. The analysis of dynamic log (Dynalog) files showed that optimization of the leaf sequence for various clinical factors can avoid beam hold-offs which break the synchronization of SMART and fail the SMART dose delivery. Through comparison between the simulated delivered fluence map and the planed fluence map, it was shown that the motion-corrected leaf sequence can greatly reduce the dose error.

  2. "Smart" nickel oxide based core-shell nanoparticles for combined chemo and photodynamic cancer therapy.

    Science.gov (United States)

    Bano, Shazia; Nazir, Samina; Munir, Saeeda; AlAjmi, Mohamed Fahad; Afzal, Muhammad; Mazhar, Kehkashan

    2016-01-01

    We report "smart" nickel oxide nanoparticles (NOPs) as multimodal cancer therapy agent. Water-dispersible and light-sensitive NiO core was synthesized with folic acid (FA) connected bovine serum albumin (BSA) shell on entrapped doxorubicin (DOX). The entrapped drug from NOP-DOX@BSA-FA was released in a sustained way (64 hours, pH=5.5, dark conditions) while a robust release was found under red light exposure (in 1/2 hour under λmax=655 nm, 50 mW/cm(2), at pH=5.5). The cell viability, thiobarbituric acid reactive substances and diphenylisobenzofuran assays conducted under light and dark conditions revealed a high photodynamic therapy potential of our construct. Furthermore, we found that the combined effect of DOX and NOPs from NOP-DOX@BSA-FA resulted in cell death approximately eightfold high compared to free DOX. We propose that NOP-DOX@BSA-FA is a potential photodynamic therapy agent and a collective drug delivery system for the systemic administration of cancer chemotherapeutics resulting in combination therapy.

  3. El relieve de los Pirineos

    OpenAIRE

    Babault, Julien

    2007-01-01

    La evolución del relieve de los Pirineos es un buen ejemplo de la interacción entre procesos superficiales y profundos. La elevada topografía media de la cadena es fruto del acortamiento y engrosamiento cortical, hoy inactivo, que se produjo principalmente durante el Paleógeno. Aunque la topografía es antigua, el escarpado relieve local es moderno. La etapa paleógena culminó con la formación de superficies de erosión con bajo relieve, formadas ya desde su inicio a gran altitud, en relación co...

  4. Glucose-Responsive Implantable Polymeric Microdevices for "Smart" Insulin Therapy of Diabetes

    Science.gov (United States)

    Chu, Michael Kok Loon

    Diabetes mellitus is a chronic illness manifested by improper blood glucose management, affecting over 350 million worldwide. As a result, all type 1 patients and roughly 20% of type 2 patients require exogenous insulin therapy to survive. Typically, daily multiple injections are taken to maintain normal glucose levels in response glucose spikes from meals. However, patient compliance and dosing accuracy can fluctuate with variation in meals, exercise, glucose metabolism or stress, leading to poor clinical outcomes. A 'smart', closed-loop insulin delivery system providing on-demand release kinetics responding to circulating glucose levels would be a boon for diabetes patients, replacing constant self monitoring and insulin. This thesis focuses on the development of a novel, 'smart' insulin microdevice that can provide on-demand insulin release in response to blood glucose levels. In the early stage, the feasibility of integrating a composite membrane with pH-responsive nanoparticles embedded in ethylcellulose membrane to provide pH-responsive in vitro release was examined and confirmed using a model drug, vitamin B12. In the second microdevice, glucose oxidase for generating pH signals from glucose oxidation, catalase and manganese dioxide nanoparticles, as peroxide scavengers, were used in a bioinorganic, albumin-based membrane cross-linked with a polydimethylsiloxane (PDMS) grid-microdevice system. This prototype device demonstrated insulin release in response to glucose levels in vitro and regulating plasma glucose in type 1 diabetic rats when implanted intraperitoneally. Advancement allowing for subcutaneous implantation and improved biocompatibility was achieved with surface modification of PDMS microdevices grafted with activated 20 kDa polyethylene glycol (PEG) chains, dramatically reducing immune response and local inflammation. When implanted subcutaneously in diabetic rats, glucose-responsive insulin delivery microdevices showed short and long

  5. Smart Porous Silicon Nanoparticles with Polymeric Coatings for Sequential Combination Therapy.

    Science.gov (United States)

    Xu, Wujun; Thapa, Rinez; Liu, Dongfei; Nissinen, Tuomo; Granroth, Sari; Närvänen, Ale; Suvanto, Mika; Santos, Hélder A; Lehto, Vesa-Pekka

    2015-11-02

    In spite of the advances in drug delivery, the preparation of smart nanocomposites capable of precisely controlled release of multiple drugs for sequential combination therapy is still challenging. Here, a novel drug delivery nanocomposite was prepared by coating porous silicon (PSi) nanoparticles with poly(beta-amino ester) (PAE) and Pluronic F-127, respectively. Two anticancer drugs, doxorubicin (DOX) and paclitaxel (PTX), were separately loaded into the core of PSi and the shell of F127. The nanocomposite displayed enhanced colloidal stability and good cytocompatibility. Moreover, a spatiotemporal drug release was achieved for sequential combination therapy by precisely controlling the release kinetics of the two tested drugs. The release of PTX and DOX occurred in a time-staggered manner; PTX was released much faster and earlier than DOX at pH 7.0. The grafted PAE on the external surface of PSi acted as a pH-responsive nanovalve for the site-specific release of DOX. In vitro cytotoxicity tests demonstrated that the DOX and PTX coloaded nanoparticles exhibited a better synergistic effect than the free drugs in inducing cellular apoptosis. Therefore, the present study demonstrates a promising strategy to enhance the efficiency of combination cancer therapies by precisely controlling the release kinetics of different drugs.

  6. Smart multifunctional drug delivery towards anticancer therapy harmonized in mesoporous nanoparticles

    Science.gov (United States)

    Baek, Seonmi; Singh, Rajendra K.; Khanal, Dipesh; Patel, Kapil D.; Lee, Eun-Jung; Leong, Kam W.; Chrzanowski, Wojciech; Kim, Hae-Won

    2015-08-01

    Nanomedicine seeks to apply nanoscale materials for the therapy and diagnosis of diseased and damaged tissues. Recent advances in nanotechnology have made a major contribution to the development of multifunctional nanomaterials, which represents a paradigm shift from single purpose to multipurpose materials. Multifunctional nanomaterials have been proposed to enable simultaneous target imaging and on-demand delivery of therapeutic agents only to the specific site. Most advanced systems are also responsive to internal or external stimuli. This approach is particularly important for highly potent drugs (e.g. chemotherapeutics), which should be delivered in a discreet manner and interact with cells/tissues only locally. Both advances in imaging and precisely controlled and localized delivery are critically important in cancer treatment, and the use of such systems - theranostics - holds great promise to minimise side effects and boost therapeutic effectiveness of the treatment. Among others, mesoporous silica nanoparticles (MSNPs) are considered one of the most promising nanomaterials for drug delivery. Due to their unique intrinsic features, including tunable porosity and size, large surface area, structural diversity, easily modifiable chemistry and suitability for functionalization, and biocompatibility, MSNPs have been extensively utilized as multifunctional nanocarrier systems. The combination or hybridization with biomolecules, drugs, and other nanoparticles potentiated the ability of MSNPs towards multifunctionality, and even smart actions stimulated by specified signals, including pH, optical signal, redox reaction, electricity and magnetism. This paper provides a comprehensive review of the state-of-the-art of multifunctional, smart drug delivery systems centered on advanced MSNPs, with special emphasis on cancer related applications.

  7. A neurochemical closed-loop controller for deep brain stimulation: toward individualized smart neuromodulation therapies.

    Directory of Open Access Journals (Sweden)

    Peter Jonas Grahn

    2014-06-01

    Full Text Available Current strategies for optimizing deep brain stimulation (DBS therapy involve multiple postoperative visits. During each visit, stimulation parameters are adjusted until desired therapeutic effects are achieved and adverse effects are minimized. However, the efficacy of these therapeutic parameters may decline with time due at least in part to disease progression, interactions between the host environment and the electrode, and lead migration. As such, development of closed-loop control systems that can respond to changing neurochemical environments, tailoring DBS therapy to individual patients, is paramount for improving the therapeutic efficacy of DBS.Evidence obtained using electrophysiology and imaging techniques in both animals and humans suggests that DBS works by modulating neural network activity. Recently, animal studies have shown that stimulation-evoked changes in neurotransmitter release that mirror normal physiology are associated with the therapeutic benefits of DBS. Therefore, to fully understand the neurophysiology of DBS and optimize its efficacy, it may be necessary to look beyond conventional electrophysiological analyses and characterize the neurochemical effects of therapeutic and non-therapeutic stimulation. By combining electrochemical monitoring and mathematical modeling techniques, we can potentially replace the trial-and-error process used in clinical programming with deterministic approaches that help attain optimal and stable neurochemical profiles. In this manuscript, we summarize the current understanding of electrophysiological and electrochemical processing for control of neuromodulation therapies. Additionally, we describe a proof-of-principle closed-loop controller that characterizes DBS-evoked dopamine changes to adjust stimulation parameters in a rodent model of DBS. The work described herein represents the initial steps toward achieving a smart neuroprosthetic system for treatment of neurologic and

  8. Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy.

    Science.gov (United States)

    Wang, Sheng; Zhang, Lei; Dong, Chunhong; Su, Lin; Wang, Hanjie; Chang, Jin

    2015-01-01

    A smart pH-responsive photodynamic therapy system based on upconversion nanoparticle loaded PEG coated polymeric lipid vesicles (RB-UPPLVs) was designed and prepared. These RB-UPPLVs which are promising agents for deep cancer photodynamic therapy applications can achieve enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy.

  9. Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy.

    Science.gov (United States)

    Kim, Jisu; Tung, Ching-Hsuan; Choi, Yongdoo

    2014-09-21

    A smart dual-targeted theranostic agent becomes highly fluorescent and phototoxic only when its linker is cleaved by tumor-associated lysosomal enzyme cathepsin B after internalization into folate receptor-positive cancer cells.

  10. Opportunistic disease and mortality in patients coinfected with hepatitis B or C virus in the strategic management of antiretroviral therapy (SMART) study

    DEFF Research Database (Denmark)

    Tedaldi, Ellen; Peters, Lars; Neuhaus, Jacquie

    2008-01-01

    BACKGROUND: In the Strategic Management of Antiretroviral Therapy (SMART) study, the risk of opportunistic disease (OD) and/or death due to any cause was elevated in the drug conservation (i.e., interrupt antiretroviral therapy until the CD4(+) cell count is

  11. Relieving idiopathic dental pain without drugs

    Directory of Open Access Journals (Sweden)

    Haryono Utomo

    2011-06-01

    Full Text Available Background: Teeth are commonly obvious source of orofacial pain. Sometimes the pain source is undetectable, thus called as idiopathic dental pain. Since dentist wants to alleviate or eliminate the pains with every effort in their mind, a lot of drugs could be prescribed. Moreover, it is make sense that endodontic treatment or even tooth extraction will be done. Unfortunately, endodontic treatment may also initiate neuropathic tooth pain that is caused by nerve extirpation, thus worsen the pain. Therefore, another cause of dental pain such as referred pain, periodontal disease, or stress which related to psychoneuroimmunology should be considered. In order to prevent from unnecessary drugs or invasive treatment such as root canal treatment and extraction, correct diagnosis and preliminary non-invasive therapies should be done. Purpose: This review elucidates several therapies that could be done by dentists for relieving idiopathic dental pain which includes massage, the “assisted drainage” therapy, modulation of psychoneuroimmunologic status and dietary omega-3. Reviews: Understanding the basic pathogenesis of pain may help in elucidating the effects of non-drug pain therapy such as muscle massage, the “assisted drainage” therapy, omega-3 and psychological stress relieving. These measures are accounted for eliminating referred pain, reducing proinflammatory mediators and relieving unwanted stress reactions consecutively. Psychological stress increases proinflammatory cytokines and thus lowered pain threshold. Conclusion: As an individual treatment, this non-drug therapy is useful in relieving idiopathic dental pain; nevertheless, if they work together the result could be more superior.Latar belakang: Gigi adalah suatu penyebab umum dari nyeri orofasial. Kadang kala penyebab nyeri tidak dapat ditemukan, sehingga disebut sebagai nyeri gigi idiopatik. Karena dokter gigi berupaya untuk mengurangi atau menghilangkan nyeri dengan segala cara

  12. Effect Observation of Er:YAG Laser Therapy in Relieving Dry Socket Pain%Er:YAG激光缓解干槽症疼痛症状效果观察

    Institute of Scientific and Technical Information of China (English)

    毕丽霞; 王亚锋; 李超

    2014-01-01

    Objective To observe the effect of Err:YAG laser therapy in relieving dry socket pain. Methods A to-tal of 58 patients with dry socket were randomly divided into treatment group(n=26)and control group(n=26). The treat-ment group underwent removal of necrotizing bone tissue by Er:YAG laser therapy,while the control group was repeatly scrubed in tooth socket with 3% hydrogen peroxide tampons,and later tamping iodoform gauzes were washed with 0. 9% sodi-um chloride injection. The pain scores of patients were recorded at 1st,3rd and 7th d of initial treatment,and 7th d odynolysis effects in the two groups were compared. Results In treatment group,the pain scores at 1 st ,3 rd and 7 th d of initial treatment were significantly lower,and 7 th d total effective rates of odynolysis were significantly higher than those in control group( P﹤0. 01). Conclusion The effect of Er:YAG laser therapy is significantly better compared with that by tamping iodoform gauze.%目的:观察 Er:YAG激光缓解干槽症疼痛症状的效果。方法将我院收治的58例干槽症随机分成观察组和对照组两组,每组26例。观察组采用Er:YAG激光去除坏死骨组织治疗,对照组使用3%过氧化氢棉球反复擦洗牙槽窝,0.9%氯化钠注射液冲洗后填塞碘仿纱条治疗,比较两组治疗第1、3、7天疼痛评分及治疗第7天疼痛缓解效果。结果观察组治疗第1、3、7天疼痛评分均低于对照组,治疗第7天疼痛缓解总有效率高于对照组,两组比较差异均有统计学意义(P﹤0.01)。结论 Er:YAG激光缓解干槽症疼痛症状效果优于填塞碘仿纱条。

  13. Percutaneous therapy of inoperable biliary stenoses and occlusions with a new self-expanding nitinol stent (SMART); Perkutane Therapie inoperabler maligner Stenosen und Verschluesse der Gallenwege mit einem neu entwickelten selbstexpandierbaren Nitinolstent (SMART)

    Energy Technology Data Exchange (ETDEWEB)

    Zorger, N.; Lenhart, M.; Strotzer, M.; Paetzel, C.; Hamer, O.; Feuerbach, S.; Link, J. [Regensburg Univ. (Germany). Inst. fuer Roentgendiagnostik

    2002-10-01

    Objective: To evaluate the treatment of malignant biliary stenoses and occlusions using a new stent. Methods: In a prospective study, 25 patients with malignant obstructive jaundice were treated with SMART stents. The handling and the quality of stent expansion were documented. Stent function was assessed 2-4 days after intervention by cholangiography and laboratory tests. A follow-up was performed three months, after stent placement. Results: All lesions were treated successfully, with a total of 35 stents implanted. In 14 patients a further balloon dilatation was performed after stent placement (8-10 mm diameter/40-80 mm length). The mean serum bilirubin level decreased significantly from 11.6 mg/dl to 4.6 mg/dl after intervention (p<0.05). The follow-up showed a mean serum bilirubin level at 4.0 mg/dl. In 4 cases (16%) a further intervention (PTCD or stent) was performed. Six patients died due to tumor progression. The stents proved to be patent in 79% (n=15) of patients alive at the time of follow-up. Conclusions: Placement of the SMART stent for the therapy of malignant biliary lesions yields good technical and clinical results. (orig.) [German] Zielsetzung: Evaluation der technischen Handhabung und Effizienz eines neu entwickelten Stents zur Therapie maligner Gallenwegsstenosen und Verschluesse. Material und Methodik: In einer prospektiven Studie wurden 25 Patienten mit Verschlussikterus bei maligner Gallengangsstenose palliativ mit dem SMART {sup trademark} -Stent behandelt. Evaluiert wurden die Handhabung des Stents und die Qualitaet der Stententfaltung. Die Stentfunktion wurde nach 2-4 Tagen ueber eine liegende interne/externe Drainage cholangiographisch sowie anhand des Verlaufs der Laborparameter kontrolliert. Eine zusaetzliche Kontrolle der Stentfunktion erfolgte nach drei Monaten. Dabei wurden das subjektive Wohlbefinden des Patienten, der aktuelle Gesamtbilirubinspiegel im Serum und die Anzahl weiterer, im Nachsorgezeitraum durchgefuehrter

  14. Mn2+-coordinated PDA@DOX/PLGA nanoparticles as a smart theranostic agent for synergistic chemo-photothermal tumor therapy

    Directory of Open Access Journals (Sweden)

    Xi J

    2017-04-01

    Full Text Available Juqun Xi,1–3 Lanyue Da,1 Changshui Yang,1 Rui Chen,4 Lizeng Gao,2 Lei Fan,5 Jie Han5 1Pharmacology Department, Medical School, Yangzhou University, 2Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, 3Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, 4Department of Nephrology, Subei People’s Hospital, Yangzhou University, 5School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China Abstract: Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are of great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn2+-coordinated doxorubicin (DOX-loaded poly(lactic-co-glycolic acid (PLGA nanoparticles as a platform for synergistic chemo-photothermal tumor therapy. DOX-loaded PLGA (DOX/PLGA nanoparticles were first synthesized through a double emulsion-solvent evaporation method, and then modified with polydopamine (PDA through self-polymerization of dopamine, leading to the formation of PDA@DOX/PLGA nanoparticles. Mn2+ ions were then coordinated on the surfaces of PDA@DOX/PLGA to obtain Mn2+-PDA@DOX/PLGA nanoparticles. In our system, Mn2+-PDA@DOX/PLGA nanoparticles could destroy tumors in a mouse model directly, by thermal energy deposition, and could also simulate the chemotherapy by thermal-responsive delivery of DOX to enhance tumor therapy. Furthermore, the coordination of Mn2+ could afford the high magnetic resonance (MR imaging capability with sensitivity to temperature and pH. The results demonstrated that Mn2+-PDA@DOX/PLGA nanoparticles had a great potential as a smart theranostic agent due to their imaging and tumor-growth-inhibition properties. Keywords: PLGA nanoparticles, polydopamine, chemo-photothermal therapy, smart theranostic agent

  15. Smart activatable and traceable dual-prodrug for image-guided combination photodynamic and chemo-therapy.

    Science.gov (United States)

    Hu, Fang; Yuan, Youyong; Mao, Duo; Wu, Wenbo; Liu, Bin

    2017-11-01

    Activatable photosensitizers (PSs) and chemo-prodrugs are highly desirable for anti-cancer therapy to reduce systemic toxicity. However, it is difficult to integrate both together into a molecular probe for combination therapy due to the complexity of introducing PS, singlet oxygen quencher, chemo-drug, chemo-drug inhibitor and active linker at the same time. To realize activatable PS and chemo-prodrug combination therapy, we develop a smart therapeutic platform in which the chemo-prodrug serves as the singlet oxygen quencher for the PS. Specifically, the photosensitizing activity and fluorescence of the PS (TPEPY-SH) are blocked by the chemo-prodrug (Mitomycin C, MMC) in the probe. Meanwhile, the cytotoxicity of MMC is also inhibited by the electron-withdrawing acyl at the nitrogen position next to the linker. Upon glutathione activation, TPEPY-S-MMC can simultaneously release active PS and MMC for combination therapy. The restored fluorescence of TPEPY-SH is also used to report the activation for both PS and MMC as well as to guide the photodynamic therapy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Interruption of antiretroviral therapy and risk of cardiovascular disease in persons with HIV-1 infection: exploratory analyses from the SMART trial

    DEFF Research Database (Denmark)

    Phillips, Andrew N; Carr, Andrew; Neuhaus, Jacquie

    2008-01-01

    BACKGROUND: The SMART trial found a raised risk of cardiovascular disease (CVD) events in patients undergoing CD4+ T cell-count guided intermittent antiretroviral therapy (ART) compared with patients on continuous ART. Exploratory analyses were performed to better understand the reasons for this ...

  17. Smart grid

    International Nuclear Information System (INIS)

    Choi, Dong Bae

    2001-11-01

    This book describes press smart grid from basics to recent trend. It is divided into ten chapters, which deals with smart grid as green revolution in energy with introduction, history, the fields, application and needed technique for smart grid, Trend of smart grid in foreign such as a model business of smart grid in foreign, policy for smart grid in U.S.A, Trend of smart grid in domestic with international standard of smart grid and strategy and rood map, smart power grid as infrastructure of smart business with EMS development, SAS, SCADA, DAS and PQMS, smart grid for smart consumer, smart renewable like Desertec project, convergence IT with network and PLC, application of an electric car, smart electro service for realtime of electrical pricing system, arrangement of smart grid.

  18. How Do Pain Relievers Work? (For Kids)

    Science.gov (United States)

    ... First Aid & Safety Doctors & Hospitals Videos Recipes for Kids Kids site Sitio para niños How the Body Works ... Español How Do Pain Relievers Work? KidsHealth / For Kids / How Do Pain Relievers Work? Print en español ¿ ...

  19. Mn2+-coordinated PDA@DOX/PLGA nanoparticles as a smart theranostic agent for synergistic chemo-photothermal tumor therapy.

    Science.gov (United States)

    Xi, Juqun; Da, Lanyue; Yang, Changshui; Chen, Rui; Gao, Lizeng; Fan, Lei; Han, Jie

    2017-01-01

    Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are of great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn 2+ -coordinated doxorubicin (DOX)-loaded poly(lactic- co -glycolic acid) (PLGA) nanoparticles as a platform for synergistic chemo-photothermal tumor therapy. DOX-loaded PLGA (DOX/PLGA) nanoparticles were first synthesized through a double emulsion-solvent evaporation method, and then modified with polydopamine (PDA) through self-polymerization of dopamine, leading to the formation of PDA@DOX/PLGA nanoparticles. Mn 2+ ions were then coordinated on the surfaces of PDA@DOX/PLGA to obtain Mn 2+ -PDA@DOX/PLGA nanoparticles. In our system, Mn 2+ -PDA@DOX/PLGA nanoparticles could destroy tumors in a mouse model directly, by thermal energy deposition, and could also simulate the chemotherapy by thermal-responsive delivery of DOX to enhance tumor therapy. Furthermore, the coordination of Mn 2+ could afford the high magnetic resonance (MR) imaging capability with sensitivity to temperature and pH. The results demonstrated that Mn 2+ -PDA@ DOX/PLGA nanoparticles had a great potential as a smart theranostic agent due to their imaging and tumor-growth-inhibition properties.

  20. Radiation stress relieving of polymer articles

    International Nuclear Information System (INIS)

    Frisch, D.C.; Weber, W.

    1982-01-01

    A method of rapidly relieving stress in an extruded or molded polymer article is disclosed. The method can be used in the preparation of printed circuit boards. An article comprised of the polymer is exposed to electromagnetic radiation, for a time period sufficient to absorb enough energy to stress relieve the polymer against stress cracking therein. Exposure occurs at one or more ranges of frequencies which are capable of being absorbed by the polymer and which are effective for stress relieving without or substantially without causing heat induced softening or flowing of the polymer. The electromagnetic radiation is selected from the ranges of infrared, microwave or ultraviolet radiation

  1. Topical Pain Relievers May Cause Burns

    Science.gov (United States)

    ... joint pain relievers containing the active ingredients menthol, methyl salicylate and capsaicin. These cases were uncovered by FDA ... people who purchase these products, Tan notes. Menthol, methyl salicylate and capsaicin create sensations of local warmth or ...

  2. "Smart" nickel oxide based core–shell nanoparticles for combined chemo and photodynamic cancer therapy

    Directory of Open Access Journals (Sweden)

    Bano S

    2016-07-01

    Full Text Available Shazia Bano,1–3,* Samina Nazir,2,* Saeeda Munir,3 Mohamed Fahad AlAjmi,4 Muhammad Afzal,1 Kehkashan Mazhar3 1Department of Physics, The Islamia University of Bahawalpur, 2Nanosciences and Technology Department, National Centre for Physics, Islamabad, 3Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan; 4College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia *These authors contributed equally to this work Abstract: We report “smart” nickel oxide nanoparticles (NOPs as multimodal cancer therapy agent. Water-dispersible and light-sensitive NiO core was synthesized with folic acid (FA connected bovine serum albumin (BSA shell on entrapped doxorubicin (DOX. The entrapped drug from NOP-DOX@BSA-FA was released in a sustained way (64 hours, pH=5.5, dark conditions while a robust release was found under red light exposure (in 1/2 hour under λmax=655 nm, 50 mW/cm2, at pH=5.5. The cell viability, thiobarbituric acid reactive substances and diphenylisobenzofuran assays conducted under light and dark conditions revealed a high photodynamic therapy potential of our construct. Furthermore, we found that the combined effect of DOX and NOPs from NOP-DOX@BSA-FA resulted in cell death approximately eightfold high compared to free DOX. We propose that NOP-DOX@BSA-FA is a potential photodynamic therapy agent and a collective drug delivery system for the systemic administration of cancer chemotherapeutics resulting in combination therapy. Keywords: light-triggered drug release, cancer, bovine serum albumin, multi-model therapy

  3. Thermal stress relieving of dilute uranium alloys

    International Nuclear Information System (INIS)

    Eckelmeyer, K.H.

    1981-01-01

    The kinetics of thermal stress relieving of uranium - 2.3 wt % niobium, uranium - 2.0 wt % molybdenum, and uranium - 0.75 wt % titanium are reported and discussed. Two temperature regimes of stress relieving are observed. In the low temperature regime (T 0 C) the process appears to be controlled by an athermal microplasticity mechanism which can be completely suppressed by prior age hardening. In the high temperature regime (300 0 C 0 C) the process appears to be controlled by a classical diffusional creep mechanism which is strongly dependent on temperature and time. Stress relieving is accelerated in cases where it occurs simultaneously with age hardening. The potential danger of residual stress induced stress corrosion cracking of uranium alloys is discussed

  4. [Development of cough-relieving herbal teas].

    Science.gov (United States)

    Puodziūniene, Gene; Janulis, Valdimaras; Milasius, Arvydas; Budnikas, Vytautas

    2005-01-01

    Cough-relieving medicinal herbs in tea are used from ancient times. Mucilage present in them or secretion produced under the influence of the active substances covers the oral and throat mucosa soothing its irritability and relieving dry, tiresome cough. It is known that the mixtures of medicinal herbs (Specias) have a complex influence on the human organism and the rational combination of medicinal herbs can improve their curative action and decrease the undesirable side effects. Having summarized the properties of those medicinal herbs we decided to create two formulations of cough-relieving herbal tea. The first formulation consists of marshmallow roots, liquorice roots and lime flowers, the second -- of marshmallow roots, Iceland moss and lime flowers. The methods for identification and assay of the active substances in the compounds were applied. The purity of the mixtures was regulated by limitation of the loss on drying, total ash, microbial contamination, contamination with radionuclides, heavy metals, pesticides and foreign matter. The expiry date of both cough-relieving herbal teas was approved to be 2 years.

  5. Smart Grid, Smart Europe

    OpenAIRE

    VITIELLO SILVIA; FULLI Gianluca; MENGOLINI Anna Maria

    2013-01-01

    Le smart grid, o reti elettriche intelligenti, aprono la strada a nuove applicazioni con conseguenze di vasta portata per l’intero sistema elettrico, tra le quali la principale è la capacità di integrare nella rete esistente più fonti di energia rinnovabili (FER), veicoli elettrici e fonti di generazione distribuita. Le smart grid inoltre garantiscono una più efficiente ed affidabile risposta alla domanda di energia, sia da un punto di vista tecnico, permettendo un monitoraggio e un controll...

  6. Thermal stress relieving of dilute uranium alloys

    International Nuclear Information System (INIS)

    Eckelmeyer, K.H.

    1980-01-01

    The kinetics of thermal stress relieving of uranium - 2.3 wt. % niobium, uranium - 2.0 wt. % molybdenum, and uranium - 0.75 wt. % titanium are reported and discussed. Two temperature regimes of stress relieving are observed. In the low temperature regime (T 0 C) the process appears to be controlled by an athermal microplasticity mechanism which can be completely suppressed by prior age hardening. In the high temperature regime (300 0 C 0 C) the process appears to be controlled by a classical diffusional creep mechanism which is strongly dependent on temperature and time. Stress relieving is accelerated in cases where it occurs simultaneously with age hardening. The potential danger of residual stress induced stress corrosion cracking of uranium alloys is discussed. It is shown that the residual stress relief which accompanies age hardening of uranium - 0.75% titanium more than compensates for the reduction in K/sub ISCC/ caused by aging. As a result, age hardening actually decreases the susceptibility of this alloy to residual stress induced stress corrosion cracking

  7. Smart assistants for smart homes

    OpenAIRE

    Rasch, Katharina

    2013-01-01

    The smarter homes of tomorrow promise to increase comfort, aid elderly and disabled people, and help inhabitants save energy. Unfortunately, smart homes today are far from this vision – people who already live in such a home struggle with complicated user interfaces, inflexible home configurations, and difficult installation procedures. Under these circumstances, smart homes are not ready for mass adoption. This dissertation addresses these issues by proposing two smart assistants for smart h...

  8. Smart Cities for Smart Children

    DEFF Research Database (Denmark)

    Rehm, Matthias; Jensen, Martin Lynge; Wøldike, Niels Peter

    This position paper presents the concept of smart cities for smart children before highlighting three concrete projects we are currently running in order to investigate different aspects of the underlying concept like social-relational interaction and situated and experiential learning.......This position paper presents the concept of smart cities for smart children before highlighting three concrete projects we are currently running in order to investigate different aspects of the underlying concept like social-relational interaction and situated and experiential learning....

  9. "Smart" theranostic lanthanide nanoprobes with simultaneous up-conversion fluorescence and tunable T1-T2 magnetic resonance imaging contrast and near-infrared activated photodynamic therapy.

    Science.gov (United States)

    Zhang, Yan; Das, Gautom Kumar; Vijayaragavan, Vimalan; Xu, Qing Chi; Padmanabhan, Parasuraman; Bhakoo, Kishore K; Selvan, Subramanian Tamil; Tan, Timothy Thatt Yang

    2014-11-07

    The current work reports a type of "smart" lanthanide-based theranostic nanoprobe, NaDyF4:Yb(3+)/NaGdF4:Yb(3+),Er(3+), which is able to circumvent the up-converting poisoning effect of Dy(3+) ions to give efficient near infrared (980 nm) triggered up-conversion fluorescence, and offers not only excellent dark T2-weighted MR contrast but also tunable bright and T1-weighted MR contrast properties. Due to the efficient up-converted energy transfer from the nanocrystals to chlorin e6 (Ce6) photosensitizers loaded onto the nanocrystals, cytotoxic singlet oxygen was generated and photodynamic therapy was demonstrated. Therefore, the current multifunctional nanocrystals could be potentially useful in various image-guided diagnoses where bright or dark MRI contrast could be selectively tuned to optimize image quality, but also as an efficient and more penetrative near-infrared activated photodynamic therapy agent.

  10. ``Smart'' theranostic lanthanide nanoprobes with simultaneous up-conversion fluorescence and tunable T1-T2 magnetic resonance imaging contrast and near-infrared activated photodynamic therapy

    Science.gov (United States)

    Zhang, Yan; Das, Gautom Kumar; Vijayaragavan, Vimalan; Xu, Qing Chi; Padmanabhan, Parasuraman; Bhakoo, Kishore K.; Tamil Selvan, Subramanian; Tan, Timothy Thatt Yang

    2014-10-01

    The current work reports a type of ``smart'' lanthanide-based theranostic nanoprobe, NaDyF4:Yb3+/NaGdF4:Yb3+,Er3+, which is able to circumvent the up-converting poisoning effect of Dy3+ ions to give efficient near infrared (980 nm) triggered up-conversion fluorescence, and offers not only excellent dark T2-weighted MR contrast but also tunable bright and T1-weighted MR contrast properties. Due to the efficient up-converted energy transfer from the nanocrystals to chlorin e6 (Ce6) photosensitizers loaded onto the nanocrystals, cytotoxic singlet oxygen was generated and photodynamic therapy was demonstrated. Therefore, the current multifunctional nanocrystals could be potentially useful in various image-guided diagnoses where bright or dark MRI contrast could be selectively tuned to optimize image quality, but also as an efficient and more penetrative near-infrared activated photodynamic therapy agent.The current work reports a type of ``smart'' lanthanide-based theranostic nanoprobe, NaDyF4:Yb3+/NaGdF4:Yb3+,Er3+, which is able to circumvent the up-converting poisoning effect of Dy3+ ions to give efficient near infrared (980 nm) triggered up-conversion fluorescence, and offers not only excellent dark T2-weighted MR contrast but also tunable bright and T1-weighted MR contrast properties. Due to the efficient up-converted energy transfer from the nanocrystals to chlorin e6 (Ce6) photosensitizers loaded onto the nanocrystals, cytotoxic singlet oxygen was generated and photodynamic therapy was demonstrated. Therefore, the current multifunctional nanocrystals could be potentially useful in various image-guided diagnoses where bright or dark MRI contrast could be selectively tuned to optimize image quality, but also as an efficient and more penetrative near-infrared activated photodynamic therapy agent. Electronic supplementary information (ESI) available. See DOI: 10.1039/c4nr01717j

  11. A smart magnetic nanoplatform for synergistic anticancer therapy: manoeuvring mussel-inspired functional magnetic nanoparticles for pH responsive anticancer drug delivery and hyperthermia

    Science.gov (United States)

    Sasikala, Arathyram Ramachandra Kurup; Ghavaminejad, Amin; Unnithan, Afeesh Rajan; Thomas, Reju George; Moon, Myeongju; Jeong, Yong Yeon; Park, Chan Hee; Kim, Cheol Sang

    2015-10-01

    We report the versatile design of a smart nanoplatform for thermo-chemotherapy treatment of cancer. For the first time in the literature, our design takes advantage of the outstanding properties of mussel-inspired multiple catecholic groups - presenting a unique copolymer poly(2-hydroxyethyl methacrylate-co-dopamine methacrylamide) p(HEMA-co-DMA) to surface functionalize the superparamagnetic iron oxide nanoparticles as well as to conjugate borate containing anticancer drug bortezomib (BTZ) in a pH-dependent manner for the synergistic anticancer treatment. The unique multiple anchoring groups can be used to substantially improve the affinity of the ligands to the surfaces of the nanoparticles to form ultrastable iron oxide nanoparticles with control over their hydrodynamic diameter and interfacial chemistry. Thus the BTZ-incorporated-bio-inspired-smart magnetic nanoplatform will act as a hyperthermic agent that delivers heat when an alternating magnetic field is applied while the BTZ-bound catechol moieties act as chemotherapeutic agents in a cancer environment by providing pH-dependent drug release for the synergistic thermo-chemotherapy application. The anticancer efficacy of these bio-inspired multifunctional smart magnetic nanoparticles was tested both in vitro and in vivo and found that these unique magnetic nanoplatforms can be established to endow for the next generation of nanomedicine for efficient and safe cancer therapy.We report the versatile design of a smart nanoplatform for thermo-chemotherapy treatment of cancer. For the first time in the literature, our design takes advantage of the outstanding properties of mussel-inspired multiple catecholic groups - presenting a unique copolymer poly(2-hydroxyethyl methacrylate-co-dopamine methacrylamide) p(HEMA-co-DMA) to surface functionalize the superparamagnetic iron oxide nanoparticles as well as to conjugate borate containing anticancer drug bortezomib (BTZ) in a pH-dependent manner for the synergistic

  12. Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population.

    Science.gov (United States)

    Rodger, Alison J; Lodwick, Rebecca; Schechter, Mauro; Deeks, Steven; Amin, Janaki; Gilson, Richard; Paredes, Roger; Bakowska, Elzbieta; Engsig, Frederik N; Phillips, Andrew

    2013-03-27

    Due to the success of antiretroviral therapy (ART), it is relevant to ask whether death rates in optimally treated HIV are higher than the general population. The objective was to compare mortality rates in well controlled HIV-infected adults in the SMART and ESPRIT clinical trials with the general population. Non-IDUs aged 20-70 years from the continuous ART control arms of ESPRIT and SMART were included if the person had both low HIV plasma viral loads (≤400 copies/ml SMART, ≤500 copies/ml ESPRIT) and high CD4(+) T-cell counts (≥350 cells/μl) at any time in the past 6 months. Standardized mortality ratios (SMRs) were calculated by comparing death rates with the Human Mortality Database. Three thousand, two hundred and eighty individuals [665 (20%) women], median age 43 years, contributed 12,357 person-years of follow-up. Sixty-two deaths occurred during follow up. Commonest cause of death was cardiovascular disease (CVD) or sudden death (19, 31%), followed by non-AIDS malignancy (12, 19%). Only two deaths (3%) were AIDS-related. Mortality rate was increased compared with the general population with a CD4(+) cell count between 350 and 499 cells/μl [SMR 1.77, 95% confidence interval (CI) 1.17-2.55]. No evidence for increased mortality was seen with CD4(+) cell counts greater than 500 cells/μl (SMR 1.00, 95% CI 0.69-1.40). In HIV-infected individuals on ART, with a recent undetectable viral load, who maintained or had recovery of CD4(+) cell counts to at least 500 cells/μl, we identified no evidence for a raised risk of death compared with the general population.

  13. Smart mobility in smart cities

    Energy Technology Data Exchange (ETDEWEB)

    Baucells, Aleta N.

    2016-07-01

    Cities are currently undergoing a transformation into the Smart concept, like Smartphones or SmartTV. Many initiatives are being developed in the framework of the Smart Cities projects, however, there is a lack of consistent indicators and methodologies to assess, finance, prioritize and implement this kind of projects. Smart Cities projects are classified according to six axes: Government, Mobility, Environment, Economy, People and Living. (Giffinger, 2007). The main objective of this research is to develop an evaluation model in relation to the mobility concept as one of the six axes of the Smart City classification and apply it to the Spanish cities. The evaluation was carried out in the 62 cities that made up in September 2015 the Spanish Network of Smart Cities (RECI- Red Española de Ciudades Inteligentes). This research is part of a larger project about Smart Cities’ evaluation (+CITIES), the project evaluates RECI’s cities in all the axes. The analysis was carried out taking into account sociodemographic indicators such as the size of the city or the municipal budget per inhabitant. The mobility’s evaluation in those cities has been focused in: sustainability mobility urban plans and measures to reduce the number of vehicles. The 62 cities from the RECI have been evaluated according to their degree of progress in several Smart Cities’ initiatives related to smart mobility. The applied methodology has been specifically made for this project. The grading scale has different ranks depending on the deployment level of smart cities’ initiatives. (Author)

  14. Electrocardiographic spatial QRS-T angle and incident cardiovascular disease in HIV-infected patients (from the Strategies for the Management of Antiretroviral Therapy [SMART] study)

    DEFF Research Database (Denmark)

    Dawood, Farah Z; Khan, Faraaz; Roediger, Mollie P

    2013-01-01

    the baseline resting 12-lead electrocardiogram of 4,453 HIV-infected patients aged 43.5 ± 9.3 years from the Strategies for Management of Antiretroviral Therapy (SMART) trial. CVD events were identified during a median follow-up of 28.7 months. Quartiles of the spatial QRS-T angle was calculated for men......Widening of the electrocardiographic (ECG) spatial QRS-T angle has been predictive of cardiovascular disease (CVD) events in the general population. However, its prognostic significance in human immunodeficiency virus (HIV)-infected patients remains unknown. The spatial QRS-T angle was derived from...... and women separately, and values in the upper quartile were considered as a widened angle (values >74° for women and >93° for men). A multivariate Cox proportional hazards analysis was used to examine the association between a widened baseline spatial QRS-T angle and incident CVD events. During 11...

  15. Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART study

    DEFF Research Database (Denmark)

    Lundgren, Jens; Emery, Sean; Neuhaus, Jacqueline A

    2008-01-01

    BACKGROUND: The SMART study randomized 5,472 human immunodeficiency virus (HIV)-infected patients with CD4+ cell counts >350 cells/microL to intermittent antiretroviral therapy (ART; the drug conservation [DC] group) versus continuous ART (the viral suppression [VS] group). In the DC group......, participants started ART when the CD4+ cell count was ART at entry inform the early use of ART. METHODS: Patients who were either ART naive (n=249) or who had not been receiving ART for >or= 6 months (n=228) were analyzed. The following......). RESULTS: A total of 477 participants (228 in the DC group and 249 in the VS group) were followed (mean, 18 months). For outcome (iv), 21 and 6 events occurred in the DC (7 in ART-naive participants and 14 in those who had not received ART for >or= 6 months) and VS (2 in ART-naive participants and 4...

  16. Smart logistics

    NARCIS (Netherlands)

    Woensel, van T.

    2012-01-01

    This lecture focuses on Smart Logistics referring to these intelligent managerial decisions related to the design, operations and control of the transportation chain processes in an efficient and cost-effective way. The starting point for Smart Logistics is the key observation that the real-life

  17. Smart Money

    DEFF Research Database (Denmark)

    Avital, Michel; Hedman, Jonas; Albinsson, Lars

    2017-01-01

    transaction costs by providing seamless real-time payments. In addition, digital legal tender that is based on blockchain technology can provide a foundation for customizable “smart money” which can be used to manage the appropriation of money and its use. In essence, the smart money is a customizable value...

  18. Association of Suboptimal Antiretroviral Therapy Adherence With Inflammation in Virologically Suppressed Individuals Enrolled in the SMART Study

    DEFF Research Database (Denmark)

    Castillo-Mancilla, Jose R; Phillips, Andrew N; Neaton, James D

    2018-01-01

    Suboptimal (ie, <100%) antiretroviral therapy (ART) adherence has been associated with heightened inflammation in cohort studies, even among people with virologic suppression. We aimed to evaluate this association among participants in the Strategies for Management of Antiretroviral Therapy (SMAR...

  19. Sensor technology for smart homes.

    Science.gov (United States)

    Ding, Dan; Cooper, Rory A; Pasquina, Paul F; Fici-Pasquina, Lavinia

    2011-06-01

    A smart home is a residence equipped with technology that observes the residents and provides proactive services. Most recently, it has been introduced as a potential solution to support independent living of people with disabilities and older adults, as well as to relieve the workload from family caregivers and health providers. One of the key supporting features of a smart home is its ability to monitor the activities of daily living and safety of residents, and in detecting changes in their daily routines. With the availability of inexpensive low-power sensors, radios, and embedded processors, current smart homes are typically equipped with a large amount of networked sensors which collaboratively process and make deductions from the acquired data on the state of the home as well as the activities and behaviors of its residents. This article reviews sensor technology used in smart homes with a focus on direct environment sensing and infrastructure mediated sensing. The article also points out the strengths and limitations of different sensor technologies, as well as discusses challenges and opportunities from clinical, technical, and ethical perspectives. It is recommended that sensor technologies for smart homes address actual needs of all stake holders including end users, their family members and caregivers, and their doctors and therapists. More evidence on the appropriateness, usefulness, and cost benefits analysis of sensor technologies for smart homes is necessary before these sensors should be widely deployed into real-world residential settings and successfully integrated into everyday life and health care services. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  20. SMART POLYMERS: INNOVATIONS IN NOVEL DRUG DELIVERY

    OpenAIRE

    Apoorva Mahajan; Geeta Aggarwal

    2011-01-01

    Smart polymers are attracting the researchers for development of novel drug delivery systems. Importance of smart polymers is rising day by day as these polymers undergo large reversible, physical or chemical changes in response to small changes in the environmental conditions such as pH, temperature, dual- stimuli, light and phase transition. Smart polymers are representing promising means for targeted drug delivery, enhanced drug delivery, gene therapy, actuator stimuli and protein folders....

  1. Percutaneous therapy of inoperable biliary stenoses and occlusions with a new self-expanding nitinol stent (SMART)

    International Nuclear Information System (INIS)

    Zorger, N.; Lenhart, M.; Strotzer, M.; Paetzel, C.; Hamer, O.; Feuerbach, S.; Link, J.

    2002-01-01

    Objective: To evaluate the treatment of malignant biliary stenoses and occlusions using a new stent. Methods: In a prospective study, 25 patients with malignant obstructive jaundice were treated with SMART stents. The handling and the quality of stent expansion were documented. Stent function was assessed 2-4 days after intervention by cholangiography and laboratory tests. A follow-up was performed three months, after stent placement. Results: All lesions were treated successfully, with a total of 35 stents implanted. In 14 patients a further balloon dilatation was performed after stent placement (8-10 mm diameter/40-80 mm length). The mean serum bilirubin level decreased significantly from 11.6 mg/dl to 4.6 mg/dl after intervention (p [de

  2. Smart biomaterials

    CERN Document Server

    Ebara, Mitsuhiro; Narain, Ravin; Idota, Naokazu; Kim, Young-Jin; Hoffman, John M; Uto, Koichiro; Aoyagi, Takao

    2014-01-01

    This book surveys smart biomaterials, exploring the properties, mechanics and characterization of hydrogels, particles, assemblies, surfaces, fibers and conjugates. Reviews applications such as drug delivery, tissue engineering, bioseparation and more.

  3. CD4+ Count-Guided Interruption of Antiretroviral Treatment. The Strategies for Mangement of Antiretroviral Therapy (SMART) Study Group

    DEFF Research Database (Denmark)

    El-Sadr, WM; Lundgren, Jens Dilling; Neaton, JD

    2006-01-01

    had a CD4+ cell count of more than 350 per cubic millimeter to the continuous use of antiretroviral therapy (the viral suppression group) or the episodic use of antiretroviral therapy (the drug conservation group). Episodic use involved the deferral of therapy until the CD4+ count decreased to less......BACKGROUND: Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance of the human immunodeficiency virus (HIV). METHODS: We randomly assigned persons infected with HIV who...... the risk of adverse events that have been associated with antiretroviral therapy. (ClinicalTrials.gov number, NCT00027352 [ClinicalTrials.gov].). Copyright 2006 Massachusetts Medical Society....

  4. Effectiveness of Compound Lidocaine Cream in Relieving the Pain by Laser Therapy for Children's Hemangiomas%复方利多卡因乳膏缓解激光治疗儿童血管瘤术中疼痛的临床分析

    Institute of Scientific and Technical Information of China (English)

    倪思利; 甘立强; 王华; 张民众

    2011-01-01

    Objective: To observe the efficacy of the compound lidocaine cream in relieving pain by laser therapy fro children's hemangiomas. Methods:According to the voluntary principle, 214 patients with hemangiomas were divided into two groups randomly.Tile experimental group were treated with compound lidocaine cream and circlopiroxed by fresh-keeping film for 1 hour, the eontrol group were not received any special treatment. Application of Visual Analogue Scale (VAS) was used to evaluate the pain of laser therapy. Results: The difference in the effective rates between the two groups was statistically different (62.5% & 11.6% ,μ =7. 3896,P < 0.05 ). Conclusions: Application of compound lidocaine cream can reduce or completely eliminate the pain from laser therapyinduced for children's hemangiomas.%目的:观察复方利多卡因乳膏缓解激光治疗儿童血管瘤术中疼痛的临床疗效.方法:将我科门诊血管瘤患儿214例,根据患者本人或家长自愿原则随机分为实验组和对照组,实验组于激光治疗术前用复方利多卡因乳膏涂抹于病灶并用保鲜膜封包1 h,对照组则于激光治疗前不做特殊处理,应用视觉模拟评分方法对治疗中的疼痛进行评估.结果:实验组与对照组有效率分别为62.5%(80例)、11.6%(10例),两组比较对疼痛的缓解差异有统计学意义(μ=7.3896,P<0.05).结论:复方利多卡因乳膏能有效缓解或彻底消除激光治疗儿童血管瘤中的疼痛.

  5. Novel concept of the smart NIR-light-controlled drug release of black phosphorus nanostructure for cancer therapy.

    Science.gov (United States)

    Qiu, Meng; Wang, Dou; Liang, Weiyuan; Liu, Liping; Zhang, Yin; Chen, Xing; Sang, David Kipkemoi; Xing, Chenyang; Li, Zhongjun; Dong, Biqin; Xing, Feng; Fan, Dianyuan; Bao, Shiyun; Zhang, Han; Cao, Yihai

    2018-01-16

    A biodegradable drug delivery system (DDS) is one the most promising therapeutic strategies for cancer therapy. Here, we propose a unique concept of light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy. A photosensitizer converts light into heat that softens and melts drug-loaded hydrogel-based nanostructures. Drug release rates can be accurately controlled by light intensity, exposure duration, BP concentration, and hydrogel composition. Owing to sufficiently deep penetration of near-infrared (NIR) light through tissues, our BP-based system shows high therapeutic efficacy for treatment of s.c. cancers. Importantly, our drug delivery system is completely harmless and degradable in vivo. Together, our work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs. If these findings are successfully translated into the clinic, millions of patients with cancer will benefit from our work.

  6. Simple, heart-smart substitutions

    Science.gov (United States)

    Coronary artery disease - heart smart substitutions; Atherosclerosis - heart smart substitutions; Cholesterol - heart smart substitutions; Coronary heart disease - heart smart substitutions; Healthy diet - heart ...

  7. Peening as a stress relieving method for welded joints

    International Nuclear Information System (INIS)

    Ferreira, M.L.R.

    1984-01-01

    The efficacy of the process of stress relieving by hammer-peening, in heavy plates of low carbon steel is analysed. The effects of peening in the mechanical properties of welded metal deposited by shield metal arc welding, using the electrodes E-6010, E-7018 and E-8018C-2, and the weld metal deposited by submerged arc welding, using the filler metals ENil and EA3, are also analysed. X-ray diffraction was used in order to verify the efficacy of peening as a stress-relieving process. The obtained results and the literature reviewed show that, peening is effective in stress relieving. (author) [pt

  8. CD4+ Count-Guided Interruption of Antiretroviral Treatment. The Strategies for Mangement of Antiretroviral Therapy (SMART) Study Group

    DEFF Research Database (Denmark)

    El-Sadr, WM; Lundgren, Jens Dilling; Neaton, JD

    2006-01-01

    BACKGROUND: Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance of the human immunodeficiency virus (HIV). METHODS: We randomly assigned persons infected with HIV wh...

  9. Smart Card

    Directory of Open Access Journals (Sweden)

    Floarea NASTASE

    2006-01-01

    Full Text Available Reforms in electronic business have presented new opportunities to use smart card technology as an enabling tool. The network-centric applications, where resources are located throughout the Internet and access to them is possible from any location, require authenticated access and secured transactions. Smart cards represent an ideal solution: they offers an additional layer of electronic security and information assurance for user authentication, confidentiality, non-repudiation, information integrity, physical access control to facilities, and logical access control to an computer systems.

  10. Smart Beta or Smart Alpha

    DEFF Research Database (Denmark)

    Winther, Kenneth Lillelund; Steenstrup, Søren Resen

    2016-01-01

    that smart beta investing probably will do better than passive market capitalization investing over time, we believe many are coming to a conclusion too quickly regarding active managers. Institutional investors are able to guide managers through benchmarks and risk frameworks toward the same well......Smart beta has become the flavor of the decade in the investment world with its low fees, easy access to rewarded risk premiums, and appearance of providing good investment results relative to both traditional passive benchmarks and actively managed funds. Although we consider it well documented......-documented smart beta risk premiums and still motivate active managers to avoid value traps, too highly priced small caps, defensives, etc. By constructing the equity portfolios of active managers that resemble the most widely used risk premiums, we show that the returns and risk-adjusted returns measures...

  11. A smart drug: a pH-responsive photothermal ablation agent for Golgi apparatus activated cancer therapy.

    Science.gov (United States)

    Xue, Fengfeng; Wen, Ying; Wei, Peng; Gao, Yilin; Zhou, Zhiguo; Xiao, Shuzhang; Yi, Tao

    2017-06-13

    We report a pH-responsive photothermal ablation agent (pH-PTT) based on cyanine dyes for photothermal therapy (PTT). The nanoparticles formed by BSA and pH-PTT preferentially accumulated in the Golgi apparatus of cancer cells compared to normal cells, and thus can be specifically activated by the acidic Golgi apparatus in cancer cells for effective PTT both ex vivo and in vivo.

  12. Smart roadside.

    Science.gov (United States)

    2012-01-01

    Smart Roadside is a system envisioned to be deployed at strategic points along commercial vehicle routes to : improve the safety, mobility, and efficiency of truck movement and operations on the roadway. It is a concept : where private- and public-se...

  13. Smart Surroundings

    NARCIS (Netherlands)

    Havinga, Paul J.M.; Jansen, P.G.; Lijding, M.E.M.; Scholten, Johan

    2004-01-01

    Ambient systems are networked embedded systems integrated with everyday environments and supporting people in their activities. These systems will create a Smart Surrounding for people to facilitate and enrich daily life and increase productivity at work. Such systems will be quite different from

  14. Hydrophilic MoSe2 Nanosheets as Effective Photothermal Therapy Agents and Their Application in Smart Devices.

    Science.gov (United States)

    Lei, Zhouyue; Zhu, Wencheng; Xu, Shengjie; Ding, Jian; Wan, Jiaxun; Wu, Peiyi

    2016-08-17

    A facile poly(vinylpyrrolidone) (PVP)-assisted exfoliation method is utilized to simultaneously exfoliate and noncovalently modify MoSe2 nanosheets. The resultant hydrophilic nanosheets are shown to be promising candidates for biocompatible photothermal therapy (PTT) agents, and they could also be encapsulated into a hydrogel matrix for some intelligent devices. This work not only provides novel insights into exfoliation and modification of transition metal dichalcogenide (TMD) nanosheets but also might spark more research into engineering multifunctional TMD-related nanocomposites, which is in favor of further exploiting the attractive properties of these emerging layered two-dimensional (2D) nanomaterials.

  15. Smart governance for smart city

    Science.gov (United States)

    Mutiara, Dewi; Yuniarti, Siti; Pratama, Bambang

    2018-03-01

    Some of the local government in Indonesia claimed they already created a smart city. Mostly the claim based of IT utilization for their governance. In general, a smart city definition is to describe a developed urban area that creates sustainable economic development and high quality of life by excelling in multiple key; economy, mobility, environment, people, living, and government. For public services, the law guarantees good governance by setting the standard for e-government implicitly including for local government or a city. Based on the arguments, this research tries to test the condition of e-government of the Indonesian city in 34 provinces. The purpose is to map e-government condition by measuring indicators of smart government, which are: transparent governance and open data for the public. This research is departing from public information disclosure law and to correspond with the existence law. By examining government transparency, the output of the research can be used to measure the effectiveness of public information disclosure law and to determine the condition of e-government in local government in which as part of a smart city.

  16. GET SMART: EPA'S SMARTE INITIATIVE

    Science.gov (United States)

    The EPA's Office of Research and Development with the assistance of the U.S.-German Bilateral Working Group and the Interstate Technology Regulatory Council (ITRC), is developing Site-specific Management Approaches and Revitalization Tools (SMART) that will help stakeholders over...

  17. HER2 Targeted Breast Cancer Therapy with Switchable "Off/On" Multifunctional "Smart" Magnetic Polymer Core-Shell Nanocomposites.

    Science.gov (United States)

    Vivek, Raju; Thangam, Ramar; Kumar, Selvaraj Rajesh; Rejeeth, Chandrababu; Kumar, Gopal Senthil; Sivasubramanian, Srinivasan; Vincent, Savariar; Gopi, Dhanaraj; Kannan, Soundarapandian

    2016-01-27

    Multifunctional magnetic polymer nanocombinations are gaining importance in cancer nanotheranostics due to their safety and their potential in delivering targeted functions. Herein, we report a novel multifunctional core-shell magnetic polymer therapeutic nanocomposites (NCs) exhibiting pH dependent "Off-On" release of drug against breast cancer cells. The NCs are intact in blood circulation ("Off" state), i.e., at physiological pH, whereas activated ("On" state) at intracellular acidic pH environment of the targeted breast cancer cells. The NCs are prepared by coating the cannonball (iron nanocore) with hydrophobic nanopockets of pH-responsive poly(d,l-lactic-co-glycolic acid) (PLGA) polymer nanoshell that allows efficient loading of therapeutics. Further, the nanocore-polymer shell is stabilized by poly(vinylpyrrolidone) (PVP) and functionalized with a targeting HER2 ligand. The prepared Her-Fe3O4@PLGA-PVP nanocomposites facilitate packing of anticancer drug (Tamoxifen) without premature release in the bloodstream, recognizing the target cells through binding of Herceptin antibody to HER2, a cell surface receptor expressed by breast cancer cells to promote HER2 receptor mediated endocytosis and finally releasing the drug at the intracellular site of tumor cells ("On" state) to induce apoptosis. The therapeutic efficiency of hemo/cytocompatible NCs drug delivery system (DDS) in terms of targeted delivery and sustained release of therapeutic agent against breast cancer cells was substantiated by in vitro and in vivo studies. The multifunctional properties of Her-Tam-Fe3O4@PLGA-PVP NCs may open up new avenues in cancer therapy through overcoming the limitations of conventional cancer therapy.

  18. Smart Factory

    DEFF Research Database (Denmark)

    Bilberg, Arne; Radziwon, Agnieszka; Grube Hansen, David

    2017-01-01

    their innovation and competitive advantage by focusing at their competences, strengths and opportunities. The project suggests innovative solutions and business models through collaboration and use of new technologies. In the Smart Factory, SMEs should be able to collaborate on new products, markets and production......, and to target their challenges and ensure sustainable growth and business in these enterprises. Therefore the focus of the Smart Factory project was to support the growth and sustainable development of the small and medium sized manufacturing industry in Denmark. The project focused on SMEs and how to improve......A large part of Danish Industry is based on Small and Medium Sized Enterprises (SMEs), which account for –99% of the companies in Denmark and about two third of the job positions (source: statistikbanken.dk) . That is why, it is so important also to focus research and development at SMEs...

  19. Smart technology

    International Nuclear Information System (INIS)

    Bruckner, D.G.

    1991-01-01

    The success of smart technology in the pursuit of the Gulf War has accentuated the awareness of how the Safeguards and Security disciplines are changing in response to new weaponry. Throughout the Department of Energy Integrated Complex (IC) Safeguards and Security efforts such as: Protection Programs Operations; Materials, Controls and Accountability; Information Security; Computer Security; Operational Security; Personnel Security, Safeguards and/or Security (S and S) surveys, and Inspections and Evaluations are undergoing a reassessment and refocusing. Some of this is in response to such things as the DOE initiated Freeze Report and the Drell Report. An important aspect is also technological, adjusting the way business is done in light of the weapons, tools and processes/procedures becoming available. This paper addresses the S and S issues with the promise of using smart technology to develop new approaches and equipment across the IC

  20. Smart Adaptive Socket to Improve Fit and Relieve Pain in Wounded Warriors

    Science.gov (United States)

    2017-10-01

    thermal dependence 1.2.b Maximum patient comfort 1.2.c improve response times for changes in volume 1.2.d Maximize range of compression region 2 the...and the prosthesis. The functionality and comfort of the prosthesis is to a great degree determined by the intimacy of this connection. Fluctuations...for a socket that accommodates a changing residual limb volume while maintaining comfort and fit. We will develop and complete preliminary real world

  1. Smart Adaptive Socket to Improve Fit and Relieve Pain in Wounded Warriors

    Science.gov (United States)

    2016-10-01

    physical connection between the user’s body and the prosthesis . The functionality and comfort of the prosthesis is to a great degree determined by the...modulus. This means that in this range the volume of the foam can be changed without causing any permanent deformation or varying how firm it feels ...average time of about 10 minutes for the foam to completely return to its original stiffness. This means that the foam will feel firm for compressions on

  2. Smart Growth and Transportation

    Science.gov (United States)

    Describes the relationship between smart growth and transportation, focusing smart and sustainable street design, transit-oriented development, parking management, sustainable transportation planning, and related resources.

  3. Deep smarts.

    Science.gov (United States)

    Leonard, Dorothy; Swap, Walter

    2004-09-01

    When a person sizes up a complex situation and rapidly comes to a decision that proves to be not just good but brilliant, you think, "That was smart." After you watch him do this a few times, you realize you're in the presence of something special. It's not raw brainpower, though that helps. It's not emotional intelligence, either, though that, too, is often involved. It's deep smarts. Deep smarts are not philosophical--they're not"wisdom" in that sense, but they're as close to wisdom as business gets. You see them in the manager who understands when and how to move into a new international market, in the executive who knows just what kind of talk to give when her organization is in crisis, in the technician who can track a product failure back to an interaction between independently produced elements. These are people whose knowledge would be hard to purchase on the open market. Their insight is based on know-how more than on know-what; it comprises a system view as well as expertise in individual areas. Because deep smarts are experienced based and often context specific, they can't be produced overnight or readily imported into an organization. It takes years for an individual to develop them--and no time at all for an organization to lose them when a valued veteran walks out the door. They can be taught, however, with the right techniques. Drawing on their forthcoming book Deep Smarts, Dorothy Leonard and Walter Swap say the best way to transfer such expertise to novices--and, on a larger scale, to make individual knowledge institutional--isn't through PowerPoint slides, a Web site of best practices, online training, project reports, or lectures. Rather, the sage needs to teach the neophyte individually how to draw wisdom from experience. Companies have to be willing to dedicate time and effort to such extensive training, but the investment more than pays for itself.

  4. Smart Pricing for Smart Grid

    OpenAIRE

    Wang, Zhimin

    2014-01-01

    Flat-rate electricity tariffs in Great Britain, which have no price variation throughout a day or a year, have been ongoing for decades to recover the cost of energy production and delivery. However, this type of electricity tariff has little incentives to encourage customers to modify their demands to suit the condition of the power supply system. Hence, it is challenged in the new smart grid environment, where demand side responses have important roles to play to encourage conventional ener...

  5. The Role of Porta Hepatis Irradiation in Relieving Malignant Obstructive Jaundice

    International Nuclear Information System (INIS)

    Yang, Kwang Mo; Suh, Hyun Suk

    1990-01-01

    We have analysed 13 patients with malignant obstructive jaundice due to metastasis who were treated with local radiation therapy to the area of porta hepatis at the Radiation Therapy Department of Paik hospital attached to the Inje University between 1984 and 1988. A good response was observed in 6 out of 7 evaluable patients receiving a total radiation dose ranging from 2600 to 5480 cGy in 2.6 to 6 weeks. A complete response was noted in 5 patients, a partial response in 1 patient, and no response in 1 patient. The overall median survival for 13 patients was 3 months. But two patients lived more than a year without recurrence of jaundice. Moderate dose, localized field radiation therapy appears to the beneficial in relieving obstructive jaundice and gives a good symptomatic relief

  6. Smart Money

    DEFF Research Database (Denmark)

    Avital, Michel; Hedman, Jonas; Albinsson, Lars

    2017-01-01

    Legal tender in the form of coins and banknotes is expected to be replaced at one point in the future by digital legal tender. This transformation is an opportunity for central banks to rethink the idea of money and overhaul the prevailing payment systems. Digital legal tender is expected to reduce...... exchange instrument that relies on computer protocols to facilitate, verify, and enforce certain conditions for its appropriation as payment, e.g. who may use the money, where, and for what. If we believe that digital legal tender will become ubiquitous, then the emergence and diffusion of smart money...

  7. How Can I Relieve My Pregnancy Leg Cramps?

    Science.gov (United States)

    ... Fitness Diseases & Conditions Infections Drugs & Alcohol School & Jobs Sports Expert Answers (Q&A) Staying Safe Videos for Educators Search English Español How Can I Relieve My Pregnancy Leg Cramps? KidsHealth / For Parents / How Can I ...

  8. Does Foot Massage Relieve Acute Postoperative Pain? A Literature Review

    Directory of Open Access Journals (Sweden)

    Chanif Chanif

    2013-01-01

    Full Text Available Purpose: This study aimed to examine the current state of knowledge regarding foot massageto determine if foot massage has an effect on relieving acute postoperative pain.Method: The following questions were used to guide this review: How does pain occur?What is the pain management modalities used in relieving acute postoperative pain? Does footmassage relieve acute postoperative pain? A comprehensive systematic search of publishedliterature and journal articles from Science Direct, CINAHL, PubMed, ProQuest and fromrelevant textbooks was conducted. The universal case entry website, Google-scholar was usedas well. The following keywords were used: foot massage, pain management, andpostoperative pain. Eight studies on foot massage and more than thirty related articles werereviewed.Result: Postoperative pain is caused by tissue damage that induces release of chemicalmediators from the surgical wound. The four processes of pain are transduction, transmission,perception and modulation. Pain medication is the goal standard for acute postoperative painrelief. In addition, foot massage is a modality that can be used in relieving acute postoperativepain. Massage stimulates large nerve fibers and dermatome layers which contain tactile andpressure receptors. The receptors subsequently transmit the nerve impulse to the centralnervous system. The gate control system in the dorsal horn is activated through the inhibitoryinterneuron, thus closing the gate. Subsequently, the brain does not receive the pain message.Eight reviewed studies demonstrated that foot massage relieves acute postoperative pain.However, there were some methodological limitations of these studies.Conclusion: It is recommended to examine the effect of foot massage on acute postoperativepain with high homogenous samples using various duration of massage and range of time forpain measurement at different settings.Key words: foot massage, pain management and postoperative pain.

  9. Smart energy and smart energy systems

    DEFF Research Database (Denmark)

    Lund, Henrik; Østergaard, Poul Alberg; Connolly, David

    2017-01-01

    In recent years, the terms “Smart Energy” and “Smart Energy Systems” have been used to express an approach that reaches broader than the term “Smart grid”. Where Smart Grids focus primarily on the electricity sector, Smart Energy Systems take an integrated holistic focus on the inclusion of more...... sectors (electricity, heating, cooling, industry, buildings and transportation) and allows for the identification of more achievable and affordable solutions to the transformation into future renewable and sustainable energy solutions. This paper first makes a review of the scientific literature within...... the field. Thereafter it discusses the term Smart Energy Systems with regard to the issues of definition, identification of solu- tions, modelling, and integration of storage. The conclusion is that the Smart Energy System concept represents a scientific shift in paradigms away from single-sector thinking...

  10. Smarter energy from smart metering to the smart grid

    CERN Document Server

    Sun, Hongjian; Poor, H Vincent; Carpanini, Laurence; Fornié, Miguel Angel Sánchez

    2016-01-01

    This book presents cutting-edge perspectives and research results in smart energy spanning multiple disciplines across four main topics: smart metering, smart grid modeling, control and optimisation, and smart grid communications and networking.

  11. Smart Houses

    Science.gov (United States)

    1987-01-01

    GWS takes plans for a new home and subjects them to intensive computerized analysis that does 10,000 calculations relative to expected heat loss and heat gain, then provides specifications designed specifically for each structure as to heating, cooling, ventilation and insulation. As construction progresses, GWS inspects the work of the electrical, plumbing and insulation contractors and installs its own Smart House Radiant Barrier. On completion of the home, GWS technicians use a machine that creates a vacuum in the house and enables computer calculation of the air exchanged, a measure of energy efficiency. Key factor is the radiant barrier, borrowed from the Apollo program. This is an adaptation of a highly effective aluminized heat shield as a radiation barrier holding in or keeping out heat, cold air and water vapor.

  12. Smart Manufacturing.

    Science.gov (United States)

    Davis, Jim; Edgar, Thomas; Graybill, Robert; Korambath, Prakashan; Schott, Brian; Swink, Denise; Wang, Jianwu; Wetzel, Jim

    2015-01-01

    Historic manufacturing enterprises based on vertically optimized companies, practices, market share, and competitiveness are giving way to enterprises that are responsive across an entire value chain to demand dynamic markets and customized product value adds; increased expectations for environmental sustainability, reduced energy usage, and zero incidents; and faster technology and product adoption. Agile innovation and manufacturing combined with radically increased productivity become engines for competitiveness and reinvestment, not simply for decreased cost. A focus on agility, productivity, energy, and environmental sustainability produces opportunities that are far beyond reducing market volatility. Agility directly impacts innovation, time-to-market, and faster, broader exploration of the trade space. These changes, the forces driving them, and new network-based information technologies offering unprecedented insights and analysis are motivating the advent of smart manufacturing and new information technology infrastructure for manufacturing.

  13. Smart Grid: Smart Customer Policy Needs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In September 2010, the International Energy Agency (IEA) held a workshop on the regulatory, market and consumer policies necessary to ensure that smart grids are deployed with adequate consideration of their risks and benefits to all stakeholders. This was one of several workshops that brought together energy providers, network operators, technology developers, regulators, customers and government policy makers to discuss smart grid technology and policy. The Smart Grid - Smart Customer Policies workshop allowed stakeholders to: gain a perspective on key issues and barriers facing early deployment of smart grids; hear expert opinion on regulatory, consumer and market challenges to smart grids; discuss smart grid-smart customer policy priorities; and build consensus on the technology and policy ingredients needed for customer-friendly smart grid deployments. Drawing on workshop discussions, the following paper lays out a logical framework to maximise the benefits and minimise the risks that smart grids pose for customers. The paper also describes key policy research questions that will guide future IEA research on this topic.

  14. Precipitating and relieving factors of migraine versus tension type headache

    OpenAIRE

    Haque, Badrul; Rahman, Kazi Mohibur; Hoque, Azharul; Hasan, ATM Hasibul; Chowdhury, Rajib Nayan; Khan, Sharif Uddin; Alam, Mondal Badrul; Habib, Mansur; Mohammad, Quazi Deen

    2012-01-01

    Abstract Background To determine the differences of precipitating and relieving factors between migraine and tension type headache. Methods This is a cross sectional study. We retrospectively reviewed the records of 250 migraine patients and 250 patients diagnosed as tension type headache from the specialized headache clinic in Dept. of Neurology, Dhaka Medical College Hospital. Data were collected through a predesigned questionnaire containing information on age, sex, social status and a pre...

  15. Smart grid security

    CERN Document Server

    Goel, Sanjay; Papakonstantinou, Vagelis; Kloza, Dariusz

    2015-01-01

    This book on smart grid security is meant for a broad audience from managers to technical experts. It highlights security challenges that are faced in the smart grid as we widely deploy it across the landscape. It starts with a brief overview of the smart grid and then discusses some of the reported attacks on the grid. It covers network threats, cyber physical threats, smart metering threats, as well as privacy issues in the smart grid. Along with the threats the book discusses the means to improve smart grid security and the standards that are emerging in the field. The second part of the b

  16. Precipitating and relieving factors of migraine versus tension type headache

    Directory of Open Access Journals (Sweden)

    Haque Badrul

    2012-08-01

    Full Text Available Abstract Background To determine the differences of precipitating and relieving factors between migraine and tension type headache. Methods This is a cross sectional study. We retrospectively reviewed the records of 250 migraine patients and 250 patients diagnosed as tension type headache from the specialized headache clinic in Dept. of Neurology, Dhaka Medical College Hospital. Data were collected through a predesigned questionnaire containing information on age, sex, social status and a predetermined list of precipitating and relieving factors. Results In this study, the female patients predominated (67%. Most of the patients were within 21–30 years age group (58.6%. About 58% of them belonged to middle class families. The common precipitating factors like stress, anxiety, activity, journey, reading, cold and warm were well distributed among both the migraine and tension type headache (TTH patients. But significant difference was demonstrated for fatigue (p  Conclusion The most frequent precipitating factors for headache appear to be identical for both migraine and TTH patients. Even though some factors like fatigue, sleep deprivation, sunlight and food significantly precipitate migraine and drug, massage are effective maneuver for relieving pain among migrianeurs.

  17. From Smart Rooms to Smart Hotels

    OpenAIRE

    Petrevska, Biljana; Cingoski, Vlatko; Gelev, Saso

    2016-01-01

    This paper gives an overview of a potential path that new hotels have to satisfy to improve their status from a hotel with smart rooms towards a full-scale smart hotel facility. It presents a possible transitional way including innovative applications based on modern information technology for ambient settings in the domain of hotel industry that aims to improve the quality of offered services towards clients, starting from the present level of smart rooms. The main objective i...

  18. Smart hydrogel functional materials

    CERN Document Server

    Chu, Liang-Yin; Ju, Xiao-Jie

    2014-01-01

    This book systematically introduces smart hydrogel functional materials with the configurations ranging from hydrogels to microgels. It serves as an excellent reference for designing and fabricating artificial smart hydrogel functional materials.

  19. Smart grid security

    Energy Technology Data Exchange (ETDEWEB)

    Cuellar, Jorge (ed.) [Siemens AG, Muenchen (Germany). Corporate Technology

    2013-11-01

    The engineering, deployment and security of the future smart grid will be an enormous project requiring the consensus of many stakeholders with different views on the security and privacy requirements, not to mention methods and solutions. The fragmentation of research agendas and proposed approaches or solutions for securing the future smart grid becomes apparent observing the results from different projects, standards, committees, etc, in different countries. The different approaches and views of the papers in this collection also witness this fragmentation. This book contains the following papers: 1. IT Security Architecture Approaches for Smart Metering and Smart Grid. 2. Smart Grid Information Exchange - Securing the Smart Grid from the Ground. 3. A Tool Set for the Evaluation of Security and Reliability in Smart Grids. 4. A Holistic View of Security and Privacy Issues in Smart Grids. 5. Hardware Security for Device Authentication in the Smart Grid. 6. Maintaining Privacy in Data Rich Demand Response Applications. 7. Data Protection in a Cloud-Enabled Smart Grid. 8. Formal Analysis of a Privacy-Preserving Billing Protocol. 9. Privacy in Smart Metering Ecosystems. 10. Energy rate at home Leveraging ZigBee to Enable Smart Grid in Residential Environment.

  20. Smart City project

    KAUST Repository

    Al Harbi, Ayman

    2018-01-24

    A \\'smart city\\' is an urban region that is highly advanced in terms of overall infrastructure, sustainable real estate, communications and market viability. It is a city where information technology is the principal infrastructure and the basis for providing essential services to residents. Yanbu Industrial City- Smart City Project - First large scale smart city in The kingdom.

  1. Smart Chips for Smart Surroundings -- 4S

    NARCIS (Netherlands)

    Schuler, Eberhard; König, Ralf; Becker, Jürgen; Rauwerda, G.K.; van de Burgwal, M.D.; Smit, Gerardus Johannes Maria; Cardoso, João M.P.; Hübner, Michael

    2011-01-01

    The overall mission of the 4S project (Smart Chips for Smart Surroundings) was to define and develop efficient flexible, reconfigurable core building blocks, including the supporting tools, for future Ambient System Devices. Reconfigurability offers the needed flexibility and adaptability, it

  2. Risk relievers and customer brand preference in the purchase of cars

    African Journals Online (AJOL)

    Seventeen risk-relievers were found to be suitable in purchase of cars. The study purported to find out the more influencing risk reducers among the chosen seventeen risk relievers in purchase of cars. Secondly the study tries to find out the impact of risk relievers based on brand choice. Seven brands namely Maruti, Tata, ...

  3. Integrative solutions for intelligent energy management. Smart metering, smart home, smart grid; Integrative Loesungsansaetze fuer ein intelligentes Energiemanagement. Smart Metering, Smart Home and Smart Grid

    Energy Technology Data Exchange (ETDEWEB)

    Jungfleisch, Achim [Hager Vertriebsgesellschaft mbH und Co. KG, Blieskastel (Germany). Marketing

    2011-07-01

    Smart Metering, Smart Home, Smart Grid - these key words significantly determine the current debate about intelligent energy management, or new energy concepts. The author of the contribution under consideration describes the interactions between Smart Metering, Smart Home and Smart Grids and the technical connection of these interactions. Thus, the compact tebis KNX demovea server connects Windows computer and the Internet with the building automation based on KNX. The technically simple combination of smart metering and smart home via Hager radio tower of the building automation provides an access to key energy data for an intelligent load management.

  4. Challenging 'smart' in smart city strategies

    DEFF Research Database (Denmark)

    Sandvik, Kjetil; Knudsen, Jacob

    and development. Focusing on processes of citizen participation and co-creation as the main driving force, we introduce a concept of 'smart city at eye level'. The introduction of new media technology and new media uses need to emerge from a profound understanding of the wants, needs and abilities of the citizens......Smart city strategies concern the improvement of economic and political efficiency and the enabling of social, cultural and urban development (Hollands 2008) and covers a variety of fields from improving infrastructures, social and cultural development, resilience strategies (e.g. green energy......), improving schools, social welfare institutions, public and private institutions etc. The 'smart' in smart city strategies implies that these efforts are accomplished by the introduction and embedding of smart media technology into the very fabric of society. This is often done in a top-down and technology...

  5. Smart Cities - Smart Homes and Smart Home Technology

    OpenAIRE

    Faanes, Erlend Kydland

    2014-01-01

    This master’s thesis consists of two articles where the first article is theoretical and the second is the empirical study. Article I The purpose with this paper is to explore and illuminate how smart home and smart home technology can contribute to enhance health and Quality of Life in elderly citizens and allow them to live longer in their home. The paper provides a brief introduction to health promotion and highlights the thesis theoretical framework and foundation of Aaron Antonov...

  6. SmartCampusAAU

    DEFF Research Database (Denmark)

    Hansen, Rene; Thomsen, Bent; Thomsen, Lone Leth

    2013-01-01

    This paper describes SmartCampusAAU - an open, extendable platform that supports the easy creation of indoor location based systems. SmartCampusAAU offers an app and backend that can be used to enable indoor positioning and navigation in any building. The SmartCampusAAU app is available on all ma...... major mobile platforms (Android, iPhone and Windows Phone) and supports both device- and infrastructure-based positioning. SmartCampusAAU also offers a publicly available OData backend that allows researchers to share radio map and location tracking data.......This paper describes SmartCampusAAU - an open, extendable platform that supports the easy creation of indoor location based systems. SmartCampusAAU offers an app and backend that can be used to enable indoor positioning and navigation in any building. The SmartCampusAAU app is available on all...

  7. Acupoint Massage in Relieving Pain after Ureteroscopic Holmium Laser Lithotripsy

    Institute of Scientific and Technical Information of China (English)

    Xia Wei-qin

    2014-01-01

    Objective: To observe the effect of acupoint massage in relieving pain after ureteroscopic holmium laser lithotripsy. Methods: Ninety-two patients undergone ureteroscopic holmium laser lithotripsy were enrolled and randomized into a treatment group and a control group, 46 in each group. Patients in the control group were given regular nursing care, while patients in the treatment group were intervened by acupoint massage in addition to the regular nursing care. The pain was evaluated by visual analogue scale (VAS) at 6 h, 12 h, and 24 h after operation, and compared between the two groups. Results:There was no significant difference in comparing the VAS score at 6 h after operation between the two groups (P>0.05). The VAS scores in the treatment group at 12 h and 24 h after operation were significantly lower than those in the control group (both P Conclusion: Acupoint massage can effectively relieve the pain after ureteroscopic holmium laser lithotripsy, reduce the use of analgesics, and promote the recovery.

  8. Neutron irradiation damage of a stress relieved TZM alloy

    International Nuclear Information System (INIS)

    Abe, K.; Masuyama, T.; Satou, M.; Hamilton, M.L.

    1992-01-01

    The objective of this work is to study defect microstructures and irradiation hardening in a stress relieved TZM alloy after irradiation in the Fast Flux Test Facility (FFTF) using the Materials Open Test Assembly (MOTA). Disk specimens of the molybdenum alloy TZM that had been stress relieved at 1199 K (929 C) for 0.9 ks (15 min.) were irradiated in the FFTF/MOTA 1F at 679, 793 and 873 K (406, 520, and 600 C) to a fast fluence of ∼9.6 x 10 22 n/cm 2 . Microstructures were observed in a transmission electron microscope (TEM). Dislocation structures consisted of isolated loops, aggregated loops (rafts) and elongated dislocations. The size of the loops increased with the irradiation temperature. Void swelling was about 1 and 2% at 793 and 873 K (520 and 600 C), respectively. A void lattice was developed in the body centered cubic (bcc) structure with a spacing of 26 - 28 nm. The fine grain size (0.5 - 2 μm) was retained following high temperature irradiation, indicating that the stress relief heat treatment may extend the material's resistance to radiation damage up to high fluence levels. Microhardness measurements indicated that irradiation hardening increased with irradiation temperature. The relationship between the microstructure and the observed hardening was determined

  9. Smart Sensors Enable Smart Air Conditioning Control

    Directory of Open Access Journals (Sweden)

    Chin-Chi Cheng

    2014-06-01

    Full Text Available In this study, mobile phones, wearable devices, temperature and human motion detectors are integrated as smart sensors for enabling smart air conditioning control. Smart sensors obtain feedback, especially occupants’ information, from mobile phones and wearable devices placed on human body. The information can be used to adjust air conditioners in advance according to humans’ intentions, in so-called intention causing control. Experimental results show that the indoor temperature can be controlled accurately with errors of less than ±0.1 °C. Rapid cool down can be achieved within 2 min to the optimized indoor capacity after occupants enter a room. It’s also noted that within two-hour operation the total compressor output of the smart air conditioner is 48.4% less than that of the one using On-Off control. The smart air conditioner with wearable devices could detect the human temperature and activity during sleep to determine the sleeping state and adjusting the sleeping function flexibly. The sleeping function optimized by the smart air conditioner with wearable devices could reduce the energy consumption up to 46.9% and keep the human health. The presented smart air conditioner could provide a comfortable environment and achieve the goals of energy conservation and environmental protection.

  10. Towards smart environments using smart objects.

    Science.gov (United States)

    Sedlmayr, Martin; Prokosch, Hans-Ulrich; Münch, Ulli

    2011-01-01

    Barcodes, RFID, WLAN, Bluetooth and many more technologies are used in hospitals. They are the technological bases for different applications such as patient monitoring, asset management and facility management. However, most of these applications exist side by side with hardly any integration and even interoperability is not guaranteed. Introducing the concept of smart objects inspired by the Internet of Things can improve the situation by separating the capabilities and functions of an object from the implementing technology such as RFID or WLAN. By aligning technological and business developments smart objects have the power to transform a hospital from an agglomeration of technologies into a smart environment.

  11. RELIEVE: A FORTRAN 77 program for numerical and graphical processing of digital topographic maps; RELIEVE: Un programa FORTRAN para procesamiento numerico y grafico de mapas topograficos digitalizados

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, J.J.; Gorostiza, C.

    1995-12-01

    The RELIEVE program was developed in order to its integration with the expert system SIRENAS, in the frame of the Industrial Risks Programme, within the CIEMAT center. For accomplishing this mentioned system, arose the necessity of an additional component unable for analyzing the topography (relieve) of the territory in which the focused site is located. That one is just the mission of the RELIEVE program. Basically RELIEVE analyses the digitalized data points of a determined topographic area, around a location of interest. The program allows us estimation by numerical techniques, using IMSL library, of the deep width, and other geometrical characteristics of the valley that are involved in. Optionally RELIEVE produces also graphical outputs concerning 3D representation of topographical map, level curves, sections of interest considered in the valley, etc., by means of the DISSPLA II library, running in the IBM system of the CIEMAT. (Author)

  12. RELIEVE: A FORTRAN 77 program for numerical and graphical processing of digital topographic maps; RELIEVE: Un programa FORTRAN para procesamiento numerico y grafico de mapas topograficos digitalizados

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, J.J.; Gorostiza, C.

    1995-07-01

    The RELIEVE program was developed in order to its integration with the expert system SIRENAS, in the frame of the Industrial Risks Programme, within the CIEMAT center. For accomplishing this mentioned system, arose the necessity of an additional component enabled for analyzing the topography (relieve) of the territory in which the focused site is located. That is just the mission of the RELIEVE program. Basically RELIEVE analyses the digitalized data points of a determinate topographic area, around a location of interest. The program allows us estimation by numerical techniques, using IMSL library, of the deep width, and other geometrical characteristics of the valley that is involved in. Optionally RELIEVE produces also graphical outputs concerning 3D representation of topographical map, level curves, sections of interest considered in the valley, etc., by means of the DISSPLA II library, running in the IBM system of the CIEMAT. (Author) 5 refs.

  13. Smart infrastructure design for Smart Cities

    OpenAIRE

    OTA, Kaoru; KUMRAI, Teerawat; DONG, Mianxiong; KISHIGAMI, Jay (Junichi); GUO, Minyi

    2017-01-01

    Intelligent Transportation Systems (ITS) is one of the keywords to describe smart cities, aiming at efficient public transport, smart parking, enhanced road safety, intelligent traffic management, onvehicle entertainment, and so on. In ITS, Roadside Unit (RSU) deployment should be well-designed due to it serves as a service provider and a gateway to the Internet for vehicular users. In this article, we propose an RSU deployment strategy which maximizes the communication coverage and reduces t...

  14. Randomised controlled trial of a digitally assisted low intensity intervention to promote personal recovery in persisting psychosis: SMART-Therapy study protocol.

    Science.gov (United States)

    Thomas, Neil; Farhall, John; Foley, Fiona; Rossell, Susan L; Castle, David; Ladd, Emma; Meyer, Denny; Mihalopoulos, Cathrine; Leitan, Nuwan; Nunan, Cassy; Frankish, Rosalie; Smark, Tara; Farnan, Sue; McLeod, Bronte; Sterling, Leon; Murray, Greg; Fossey, Ellie; Brophy, Lisa; Kyrios, Michael

    2016-09-07

    Psychosocial interventions have an important role in promoting recovery in people with persisting psychotic disorders such as schizophrenia. Readily available, digital technology provides a means of developing therapeutic resources for use together by practitioners and mental health service users. As part of the Self-Management and Recovery Technology (SMART) research program, we have developed an online resource providing materials on illness self-management and personal recovery based on the Connectedness-Hope-Identity-Meaning-Empowerment (CHIME) framework. Content is communicated using videos featuring persons with lived experience of psychosis discussing how they have navigated issues in their own recovery. This was developed to be suitable for use on a tablet computer during sessions with a mental health worker to promote discussion about recovery. This is a rater-blinded randomised controlled trial comparing a low intensity recovery intervention of eight one-to-one face-to-face sessions with a mental health worker using the SMART website alongside routine care, versus an eight-session comparison condition, befriending. The recruitment target is 148 participants with a schizophrenia-related disorder or mood disorder with a history of psychosis, recruited from mental health services in Victoria, Australia. Following baseline assessment, participants are randomised to intervention, and complete follow up assessments at 3, 6 and 9 months post-baseline. The primary outcome is personal recovery measured using the Process of Recovery Questionnaire (QPR). Secondary outcomes include positive and negative symptoms assessed with the Positive and Negative Syndrome Scale, subjective experiences of psychosis, emotional symptoms, quality of life and resource use. Mechanisms of change via effects on self-stigma and self-efficacy will be examined. This protocol describes a novel intervention which tests new therapeutic methods including in-session tablet computer use and

  15. Smart Information Management in Health Big Data.

    Science.gov (United States)

    Muteba A, Eustache

    2017-01-01

    The smart information management system (SIMS) is concerned with the organization of anonymous patient records in a big data and their extraction in order to provide needful real-time intelligence. The purpose of the present study is to highlight the design and the implementation of the smart information management system. We emphasis, in one hand, the organization of a big data in flat file in simulation of nosql database, and in the other hand, the extraction of information based on lookup table and cache mechanism. The SIMS in the health big data aims the identification of new therapies and approaches to delivering care.

  16. Synergisms between smart metering and smart grid; Synergien zwischen Smart Metering und Smart Grid

    Energy Technology Data Exchange (ETDEWEB)

    Maas, Peter [IDS GmbH, Ettlingen (Germany)

    2010-04-15

    With the implementation of a smart metering solution, it is not only possible to acquire consumption data for billing but also to acquire relevant data of the distribution grid for grid operation. There is still a wide gap between the actual condition and the target condition. Synergies result from the use of a common infrastructure which takes account both of the requirements of smart metering and of grid operation. An open architecture also enables the future integration of further applications of the fields of smart grid and smart home. (orig.)

  17. Smart Location Database - Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Smart Location Database (SLD) summarizes over 80 demographic, built environment, transit service, and destination accessibility attributes for every census block...

  18. Smart space technology innovations

    CERN Document Server

    Chen, Mu-Yen

    2013-01-01

    Recently, ad hoc and wireless communication technologies have made available the device, service and information rich environment for users. Smart Space and ubiquitous computing extend the ""Living Lab"" vision of everyday objects and provide context-awareness services to users in smart living environments. This ebook investigates smart space technology and its innovations around the Living Labs. The final goal is to build context-awareness smart space and location-based service applications that integrate information from independent systems which autonomously and securely support human activ

  19. Conceptualizing smart service systems

    DEFF Research Database (Denmark)

    Beverungen, Daniel; Müller, Oliver; Matzner, Martin

    2017-01-01

    Recent years have seen the emergence of physical products that are digitally networked with other products and with information systems to enable complex business scenarios in manufacturing, mobility, or healthcare. These “smart products”, which enable the co-creation of “smart service” that is b......Recent years have seen the emergence of physical products that are digitally networked with other products and with information systems to enable complex business scenarios in manufacturing, mobility, or healthcare. These “smart products”, which enable the co-creation of “smart service......” that is based on monitoring, optimization, remote control, and autonomous adaptation of products, profoundly transform service systems into what we call “smart service systems”. In a multi-method study that includes conceptual research and qualitative data from in-depth interviews, we conceptualize “smart...... service” and “smart service systems” based on using smart products as boundary objects that integrate service consumers’ and service providers’ resources and activities. Smart products allow both actors to retrieve and to analyze aggregated field evidence and to adapt service systems based on contextual...

  20. The People's Smart Sculpture

    OpenAIRE

    Koplin, Martin; Nedelkovski, Igor; Salo, Kari

    2016-01-01

    The People’s Smart Sculpture (PS2) panel discusses future oriented approaches in smart media-art, developed, designed and exploited for artistic and public participation in the change and re-design of our living environment. The actual debate about a smart future is not taking into account any idea of media art as an instrument for to realize the social sculpture, mentioned by Beuys [1] or as social sculpture itself. The People’s Smart Sculpture is the only large scale Creative Europe media-a...

  1. Smart Location Database - Download

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Smart Location Database (SLD) summarizes over 80 demographic, built environment, transit service, and destination accessibility attributes for every census block...

  2. Reward memory relieves anxiety-related behavior through synaptic strengthening and protein kinase C in dentate gyrus.

    Science.gov (United States)

    Lei, Zhuofan; Liu, Bei; Wang, Jin-Hui

    2016-04-01

    Anxiety disorders are presumably associated with negative memory. Psychological therapies are widely used to treat this mental deficit in human beings based on the view that positive memory competes with negative memory and relieves anxiety status. Cellular and molecular processes underlying psychological therapies remain elusive. Therefore, we have investigated its mechanisms based on a mouse model in which food reward at one open-arm of the elevated plus-maze was used for training mice to form reward memory and challenge the open arms. Mice with the reward training showed increased entries and stay time in reward open-arm versus neutral open-arm as well as in open-arms versus closed-arms. Accompanying with reward memory formation and anxiety relief, glutamatergic synaptic transmission in dentate gyrus in vivo and dendritic spines in granule cells became upregulated. This synaptic up-regulation was accompanied by the expression of more protein kinase C (PKC) in the dendritic spines. The inhibition of PKC by chelerythrine impaired the formation of reward memory, the relief of anxiety-related behavior and the up-regulation of glutamate synapses. Our results suggest that reward-induced positive memory relieves mouse anxiety-related behavior by strengthening synaptic efficacy and PKC in the hippocampus, which imply the underlying cellular and molecular processes involved in the beneficial effects of psychological therapies treating anxiety disorders. © 2015 Wiley Periodicals, Inc.

  3. [Relieving pre-exam anxiety syndrome with wrist-ankle acupuncture: a randomized controlled trial].

    Science.gov (United States)

    Shu, Shi; Li, Tong-ming; Fang, Fan-fu; He, Hou-luo; Zhou, Qing-hui; Gu, Wei; Zhou, Shuang

    2011-06-01

    Pre-exam anxiety syndrome is a common condition occurring in pre-exam students and directly affects their examination performance and physical state. Wrist-ankle acupuncture has significant therapeutic effects in treating mental disorders and may also relieve the symptoms of pre-exam anxiety syndrome. To assess the therapeutic effect of wrist-ankle acupuncture on pre-exam anxiety syndrome. A total of 60 students who met the inclusion criteria of pre-exam anxiety syndrome were enrolled from a university in Shanghai and they were randomly divided into treatment group and control group. There were 30 cases in each group, and no case failed to follow-up. In the treatment group, wrist-ankle acupuncture was adopted to point upper 1 bilaterally (impression between flexor carpi ulnaris tendon and ulnar margin), and there was no requirement for Deqi (arrival of qi). In the control group, sham acupuncture was adopted. The treatment was applied 3 times totally in both groups one week before the exam, once every other day, each time with the needles retained for 30 min. The therapeutic effects were compared between two groups. Before and after 3 treatments, Sarason Test Anxiety Scale (TAS) and Expectation and Treatment Credibility Scale (ETCS) were measured and evaluated. The therapeutic effect experienced by the treatment group was better than that of the control group (PETCS before treatment between the two groups. The scores of TAS after treatment in two groups were higher than those before treatment (PETCS than those in the control group (P<0.05, P<0.01). No adverse reaction was reported. Wrist-ankle acupuncture can relieve the symptoms of pre-exam anxiety syndrome significantly, and this therapy is highly safe.

  4. Electricity Markets, Smart Grids and Smart Buildings

    Science.gov (United States)

    Falcey, Jonathan M.

    A smart grid is an electricity network that accommodates two-way power flows, and utilizes two-way communications and increased measurement, in order to provide more information to customers and aid in the development of a more efficient electricity market. The current electrical network is outdated and has many shortcomings relating to power flows, inefficient electricity markets, generation/supply balance, a lack of information for the consumer and insufficient consumer interaction with electricity markets. Many of these challenges can be addressed with a smart grid, but there remain significant barriers to the implementation of a smart grid. This paper proposes a novel method for the development of a smart grid utilizing a bottom up approach (starting with smart buildings/campuses) with the goal of providing the framework and infrastructure necessary for a smart grid instead of the more traditional approach (installing many smart meters and hoping a smart grid emerges). This novel approach involves combining deterministic and statistical methods in order to accurately estimate building electricity use down to the device level. It provides model users with a cheaper alternative to energy audits and extensive sensor networks (the current methods of quantifying electrical use at this level) which increases their ability to modify energy consumption and respond to price signals The results of this method are promising, but they are still preliminary. As a result, there is still room for improvement. On days when there were no missing or inaccurate data, this approach has R2 of about 0.84, sometimes as high as 0.94 when compared to measured results. However, there were many days where missing data brought overall accuracy down significantly. In addition, the development and implementation of the calibration process is still underway and some functional additions must be made in order to maximize accuracy. The calibration process must be completed before a reliable

  5. Drug therapy smartens up

    Science.gov (United States)

    Martin, Christian

    2015-11-01

    The submission of the first 'smart pill' for market approval, combined with progress in the European nanomedicine landscape, illustrates the positive outlook for drug therapy and health monitoring, explains Christian Martin.

  6. Modelo digital del relieve original del yacimiento Punta Gorda

    Directory of Open Access Journals (Sweden)

    Luis F. Mena-Matos

    2003-03-01

    Full Text Available Se obtiene un MDT del relieve original del yacimiento de níquel Punta Gorda, transformado por veinte años de explotación minera. Se parte de tres fuentes de información: la red de exploración espaciada a 33,33 m, precisa pero poco densa; la red de explotación espaciada a 16,67 m, densa pero imprecisa, y la tercera es la carta topográfica a escala 1: 5 000, digitalizada con vectorización semiautomática sobre las imágenes rectificadas con polinomios de 2do y 3do órdenes; ésta es poco precisa, pero representativa de la variabilidad espacial del terreno. Se compararon las fuentes de información tomando como referencia la carta topográfica y en función de estas diferencias se planificó un levantamiento de campo para el control de errores. Se compararon los puntos de control con las fuentes de información y algunas de sus combinaciones, convertidas en grids espaciados a 2 m de distancia, estos grids fueron estimados mediante interpolación lineal con triangulación de Delaunay, Kriging Ordinario (KO y Kriging con Drift Externo (KDE. Se empleó también la técnica de Jackknife, y se tomaron como destino los puntos de comprobación. Los mejores resultados se obtuvieron con KDE tomando como variable la cota de la red de explotación y como drift la carta topográfica 1: 5 000, a ésta se agregó la red de explotación para densificar la información del drift. Se eliminaron los datos no robustos y se obtuvo un MDT usando la precisión de la red de exploración y la información del comportamiento espacial del relieve brindados por la red de explotación y la carta topográfica 1: 5 000.

  7. Smart SDHW systems

    DEFF Research Database (Denmark)

    Andersen, Elsa

    2000-01-01

    The aim of the project is to develop smart solar domestic hot water (SDHW) systems. A smart SDHW is a system in which the domestic water can bee heated both by solar collectors and by an auxiliary energy supply system. The auxiliary energy supply system heats up the hot-water tank from the top an...

  8. Making Smart Food Choices

    Science.gov (United States)

    ... turn JavaScript on. Feature: Healthy Aging Making Smart Food Choices Past Issues / Winter 2015 Table of Contents Everyday ... NIH www.nia.nih.gov/Go4Life Making Smart Food Choices To maintain a healthy weight, balance the calories ...

  9. Playing the Smart Card.

    Science.gov (United States)

    Zuzack, Christine A.

    1997-01-01

    Enhanced magnetic strip cards and "smart cards" offer varied service options to college students. Enhanced magnetic strip cards serve as cash cards and provide access to services. Smart cards, which resemble credit cards but contain a microchip, can be used as phone cards, bus passes, library cards, admission tickets, point-of-sale debit…

  10. SMART Boards Rock

    Science.gov (United States)

    Giles, Rebecca M.; Shaw, Edward L.

    2011-01-01

    SMART Board is a technology that combines the functionality of a whiteboard, computer, and projector into a single system. The interactive nature of the SMART Board offers many practical uses for providing an introduction to or review of material, while the large work area invites collaboration through social interaction and communication. As a…

  11. Smart grid in China

    DEFF Research Database (Denmark)

    Sommer, Simon; Ma, Zheng; Jørgensen, Bo Nørregaard

    2015-01-01

    China is planning to transform its traditional power grid in favour of a smart grid, since it allows a more economically efficient and a more environmentally friendly transmission and distribution of electricity. Thus, a nationwide smart grid is likely to save tremendous amounts of resources...

  12. Smart Icon Cards

    Science.gov (United States)

    Dunbar, Laura

    2015-01-01

    Icons are frequently used in the music classroom to depict concepts in a developmentally appropriate way for students. SmartBoards provide music educators yet another way to share these manipulatives with students. This article provides a step-by-step tutorial to create Smart Icon Cards using the folk song "Lucy Locket."

  13. Planning in Smart Grids

    NARCIS (Netherlands)

    Bosman, M.G.C.

    2012-01-01

    The electricity supply chain is changing, due to increasing awareness for sustainability and an improved energy efficiency. The traditional infrastructure where demand is supplied by centralized generation is subject to a transition towards a Smart Grid. In this Smart Grid, sustainable generation

  14. Smart Fabrics Technology Development

    Science.gov (United States)

    Simon, Cory; Potter, Elliott; Potter, Elliott; McCabe, Mary; Baggerman, Clint

    2010-01-01

    Advances in Smart Fabrics technology are enabling an exciting array of new applications for NASA exploration missions, the biomedical community, and consumer electronics. This report summarizes the findings of a brief investigation into the state of the art and potential applications of smart fabrics to address challenges in human spaceflight.

  15. Smart City Planning

    DEFF Research Database (Denmark)

    Ekman, Ulrik

    2018-01-01

    This article reflects on the challenges for urban planning posed by the emergence of smart cities in network societies. In particular, it reflects on reductionist tendencies in existing smart city planning. Here the concern is with the implications of prior reductions of complexity which have been...... undertaken by placing primacy in planning on information technology, economical profit, and top-down political government. Rather than pointing urban planning towards a different ordering of these reductions, this article argues in favor of approaches to smart city planning via complexity theory....... Specifically, this article argues in favor of approaching smart city plans holistically as topologies of organized complexity. Here, smart city planning is seen as a theory and practice engaging with a complex adaptive urban system which continuously operates on its potential. The actualizations in the face...

  16. Smart Sustainable Islands VS Smart Sustainable Cities

    Science.gov (United States)

    Pantazis, D. N.; Moussas, V. C.; Murgante, B.; Daverona, A. C.; Stratakis, P.; Vlissidis, N.; Kavadias, A.; Economou, D.; Santimpantakis, K.; Karathanasis, B.; Kyriakopoulou, V.; Gadolou, E.

    2017-09-01

    This paper has several aims: a) the presentation of a critical analysis of the terms "smart sustainable cities" and "smart sustainable islands" b) the presentation of a number of principles towards to the development methodological framework of concepts and actions, in a form of a manual and actions guide, for the smartification and sustainability of islands. This kind of master plan is divided in thematic sectors (key factors) which concern the insular municipalities c) the creation of an island's smartification and sustainability index d) the first steps towards the creation of a portal for the presentation of our smartification actions manual, together with relative resources, smart applications examples, and, in the near future the first results of our index application in a number of Greek islands and e) the presentation of some proposals of possible actions towards their sustainable development and smartification for the municipalities - islands of Paros and Antiparos in Greece, as case studies.

  17. Smart houses for a smart grid

    Energy Technology Data Exchange (ETDEWEB)

    Kok, J.K.; Warmer, C.J. [ECN Efficiency and Infrastructure, Petten (Netherlands); Karnouskos, S.; Weidlich, A. [SAP Research, Karlsruhe Institute of Technology, (Germany); Nestle, D.; Strauss, P. [The Institut fuer Solare Energieversorgungstechnik ISET, University of Kassel, Kassel (Germany); Dimeas, A.; Hatziargyriou, N. [Institute Computers Communications Systems ICCS, National Technical University of Athens NTUA, Athens (Greece); Buchholz, B.; Drenkard, S. [MVV Energie, Berlin (Germany); Lioliou, V. [Public Power Corporation PPC, Athens (Greece)

    2009-08-15

    Innovative technologies and concepts will emerge as we move towards a more dynamic, service-based, market-driven infrastructure, where energy efficiency and savings can be facilitated by interactive distribution networks. A new generation of fully interactive Information and Communication Technologies (ICT) infrastructure has to be developed to support the optimal exploitation of the changing, complex business processes and to enable the efficient functioning of the deregulated energy market for the benefit of citizens and businesses. The architecture of such distributed system landscapes must be designed and validated, standards need to be created and widely supported, and comprehensive, reliable IT applications will need to be implemented. The collaboration between a smart house and a smart grid is a promising approach which, with the help of ICT can fully unleash the capabilities of the smart electricity network.

  18. Pressure relieving support surfaces (PRESSURE) trial: cost effectiveness analysis.

    Science.gov (United States)

    Iglesias, Cynthia; Nixon, Jane; Cranny, Gillian; Nelson, E Andrea; Hawkins, Kim; Phillips, Angela; Torgerson, David; Mason, Su; Cullum, Nicky

    2006-06-17

    To assess the cost effectiveness of alternating pressure mattresses compared with alternating pressure overlays for the prevention of pressure ulcers in patients admitted to hospital. Cost effectiveness analysis carried out alongside the pressure relieving support surfaces (PRESSURE) trial; a multicentre UK based pragmatic randomised controlled trial. 11 hospitals in six UK NHS trusts. Intention to treat population comprising 1971 participants. Kaplan Meier estimates of restricted mean time to development of pressure ulcers and total costs for treatment in hospital. Alternating pressure mattresses were associated with lower overall costs (283.6 pounds sterling per patient on average, 95% confidence interval--377.59 pounds sterling to 976.79 pounds sterling) mainly due to reduced length of stay in hospital, and greater benefits (a delay in time to ulceration of 10.64 days on average,--24.40 to 3.09). The differences in health benefits and total costs for hospital stay between alternating pressure mattresses and alternating pressure overlays were not statistically significant; however, a cost effectiveness acceptability curve indicated that on average alternating pressure mattresses compared with alternating pressure overlays were associated with an 80% probability of being cost saving. Alternating pressure mattresses for the prevention of pressure ulcers are more likely to be cost effective and are more acceptable to patients than alternating pressure overlays.

  19. Emergency pulpotomy in relieving acute dental pain among Tanzanian patients

    Directory of Open Access Journals (Sweden)

    Simon Elison NM

    2006-01-01

    Full Text Available Abstract Background In Tanzania, oral health services are mostly in the form of dental extractions aimed at alleviating acute dental pain. Conservative methods of alleviating acute dental pain are virtually non-existent. Therefore, it was the aim of this study to determine treatment success of emergency pulpotomy in relieving acute dental pain. Methods Setting: School of Dentistry, Muhimbili National Hospital, Dar es Salaam, Tanzania. Study design: Longitudinal study. Participants: 180 patients who presented with dental pain due to acute irreversible pulpitis during the study period between July and August 2001. Treatment and evaluation: Patients were treated by emergency pulpotomy on permanent posterior teeth and were evaluated for pain after one, three and six week's post-treatment. Pain, if present, was categorised as either mild or acute. Results Of the patients with treated premolars, 25 (13.9% patients did not experience pain at all while 19 (10.6% experienced mild pain. None of the patients with treated premolars experienced acute pain. Among 136 patients with treated molars 56 (31% did not experience any pain, 76 (42.2% experienced mild pain and the other 4 (2.2% suffered acute pain. Conclusion The short term treatment success of emergency pulpotomy was high being 100% for premolars and 97.1% for molars, suggesting that it can be recommended as a measure to alleviate acute dental pain while other conservative treatment options are being considered.

  20. Relieving Pain using Dose-Extending Placebos: A Scoping Review

    Science.gov (United States)

    Colloca, Luana; Enck, Paul; DeGrazia, David

    2017-01-01

    Placebos are often used by clinicians, usually deceptively and with little rationale or evidence of benefit, making their use ethically problematic. In contrast with their typical current use, a provocative line of research suggests that placebos can be intentionally exploited to extend analgesic therapeutic effects. Is it possible to extend the effects of drug treatments by interspersing placebos? We reviewed a database of placebo studies, searching for studies that indicate that placebos given after repeated administration of active treatments acquire medication-like effects. We found a total of 22studies in both animals and humans hinting of evidence that placebos may work as a sort of dose extender of active painkillers. Wherever effective in relieving clinical pain, such placebo use would offer several advantages. First, extending the effects of a painkiller through the use of placebos may reduce total drug intake and side effects. Second, dose-extending placebos may decrease patient dependence. Third, using placebos along with active medication, for part of the course of treatment, should limit dose escalation and lower costs. Importantly, provided that nondisclosure is pre-authorized in the informed consent process and that robust evidence indicates therapeutic benefit comparable to that of standard full-dose therapeutic regimens, introducing dose-extending placebos into the clinical arsenal should be considered. This novel prospect of placebo use has the potential to change our general thinking about painkiller treatments, the typical regimens of painkiller applications, and the ways in which treatments are evaluated. PMID:27023425

  1. Smart IR780 Theranostic Nanocarrier for Tumor-Specific Therapy: Hyperthermia-Mediated Bubble-Generating and Folate-Targeted Liposomes.

    Science.gov (United States)

    Guo, Fang; Yu, Meng; Wang, Jinping; Tan, Fengping; Li, Nan

    2015-09-23

    The therapeutic effectiveness of chemotherapy was hampered by dose-limiting toxicity and was optimal only when tumor cells were subjected to a maximum drug exposure. The purpose of this work was to design a dual-functional thermosensitive bubble-generating liposome (BTSL) combined with conjugated targeted ligand (folate, FA) and photothermal agent (IR780), to realize enhanced therapeutic and diagnostic functions. This drug carrier was proposed to target tumor cells owing to FA-specific binding, followed by triggering drug release due to the decomposition of encapsulated ammonium bicarbonate (NH4HCO3) (generated CO2 bubbles) by being subjected to near-infrared (near-IR) laser irradiation, creating permeable defects in the lipid bilayer that rapidly release drug. In vitro temperature-triggered release study indicated the BTSL system was sensitive to heat triggering, resulting in rapid drug release under hyperthermia. For in vitro cellular uptake experiments, different results were observed on human epidermoid carcinoma cells (KB cells) and human lung cancer cells (A549 cells) due to their different (positive or negative) response to FA receptor. Furthermore, in vivo biodistribution analysis and antitumor study indicated IR780-BTSL-FA could specifically target KB tumor cells, exhibiting longer circulation time than free drug. In the pharmacodynamics experiments, IR780-BTSL-FA efficiently inhibited tumor growth in nude mice with no evident side effect to normal tissues and organs. Results of this study demonstrated that the constructed smart theranostic nanocarrier IR780-BTSL-FA might contribute to establishment of tumor-selective and effective chemotherapy.

  2. 31 CFR 585.521 - Donations of food to relieve human suffering authorized.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Donations of food to relieve human... Donations of food to relieve human suffering authorized. (a) Specific licenses may be issued on a case-by.... (b) In general, specific licenses will only be granted for donations of food to be provided through...

  3. Psychological stress-relieving effects of chewing - Relationship between masticatory function-related factors and stress-relieving effects.

    Science.gov (United States)

    Tasaka, Akinori; Kikuchi, Manaki; Nakanishi, Kousuke; Ueda, Takayuki; Yamashita, Shuichiro; Sakurai, Kaoru

    2018-01-01

    The objective of the present study was to investigate the relationship between masticatory function-related factors (masticatory performance, occlusal contact area, maximum bite force, number of chewing strokes, and muscle activity) and the stress-relieving effects of chewing. A total of 28 healthy male subjects were instructed to rest or chew for 10min after 30min of stress loading with arithmetic calculations. Their stress state was assessed by measuring salivary cortisol levels. Saliva was collected at three time points: before stress loading, immediately after stress loading, and 10min after stress loading. Compared to resting, chewing produced a significantly greater reduction in the rate of change in salivary cortisol levels 10min after stress loading. A negative correlation was observed between the rate of decrease in salivary cortisol levels and the number of chewing strokes. No significant correlation was observed between the rate of decrease in salivary cortisol levels and other measurement items. In healthy dentulous people, the number of chewing strokes has been shown to be a masticatory function-related factor that affects stress relief from chewing, suggesting the possibility that more appropriate chewing would produce a greater effect psychological stress relief. Copyright © 2017 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  4. Towards a smart home framework

    OpenAIRE

    Alam, Muddasser; Alan, Alper; Rogers, Alex; Ramchurn, Sarvapali D.

    2013-01-01

    We present our Smart Home Framework (SHF) which simplifies the modelling, prototyping and simulation of smart infrastructure (i.e., smart home and smart communities). It provides the buildings blocks (e.g., home appliances) that can be extended and assembled together to build a smart infrastructure model to which appropriate AI techniques can be applied. This approach enables rapid modelling where new research initiatives can build on existing work.

  5. Application of the smart portal in transportation

    International Nuclear Information System (INIS)

    Kercel, S.W.; Baylor, V.M.; Dress, W.B.; Hickerson, T.W.; Jatko, W.B.; Labaj, L.E.; Muhs, J.D.; Pack, R.M.

    1996-01-01

    Under a program sponsored by the Department of Energy, the Oak Ridge complex is developed a ''Portal-of-the-Future'', or ''smart portal''. This is a security portal for vehicular traffic which is intended to quickly detect explosives, hidden passengers, etc. It uses several technologies, including microwaves, weigh-in-motion, digital image processing, and electroacoustic wavelet-based heartbeat detection. A novel component of particular interest is the Enclosed Space Detection System (ESDS), which detects the presence of persons hiding in a vehicle. The system operates by detecting the presence of a human ballistocardiographic signature. Each time the heart beats, it generates a small but measurable shock wave that propagates through the body. The wave, whose graph is called a ballistocardiogram, is the mechanical analog of the electrocardiogram, which is routinely used for medical diagnosis. The wave is, in turn, coupled to any surface or object with which the body is in contact. If the body is located in an enclosed space, this will result in a measurable deflection of the surface of the enclosure. Independent testing has shown ESDS to be highly reliable. The technologies used in the smart portal operate in real time and allow vehicles to be checked through the portal in much less time than would be required for human inspection. Although not originally developed for commercial transportation, the smart portal has the potential to solve several transportation problems. It could relieve congestion at international highway border crossings by reducing the time required to inspect each vehicle while increasing the level of security. It can reduce highway congestion at the entrance of secure facilities such as prisons. Also, it could provide security at intermodal transfer points, such as airport parking lots and car ferry terminals

  6. Application of the smart portal in transportation

    Energy Technology Data Exchange (ETDEWEB)

    Kercel, S.W.; Baylor, V.M.; Dress, W.B.; Hickerson, T.W.; Jatko, W.B.; Labaj, L.E.; Muhs, J.D.; Pack, R.M.

    1996-12-31

    Under a program sponsored by the Department of Energy, the Oak Ridge complex is developed a ``Portal-of-the-Future``, or ``smart portal``. This is a security portal for vehicular traffic which is intended to quickly detect explosives, hidden passengers, etc. It uses several technologies, including microwaves, weigh-in-motion, digital image processing, and electroacoustic wavelet-based heartbeat detection. A novel component of particular interest is the Enclosed Space Detection System (ESDS), which detects the presence of persons hiding in a vehicle. The system operates by detecting the presence of a human ballistocardiographic signature. Each time the heart beats, it generates a small but measurable shock wave that propagates through the body. The wave, whose graph is called a ballistocardiogram, is the mechanical analog of the electrocardiogram, which is routinely used for medical diagnosis. The wave is, in turn, coupled to any surface or object with which the body is in contact. If the body is located in an enclosed space, this will result in a measurable deflection of the surface of the enclosure. Independent testing has shown ESDS to be highly reliable. The technologies used in the smart portal operate in real time and allow vehicles to be checked through the portal in much less time than would be required for human inspection. Although not originally developed for commercial transportation, the smart portal has the potential to solve several transportation problems. It could relieve congestion at international highway border crossings by reducing the time required to inspect each vehicle while increasing the level of security. It can reduce highway congestion at the entrance of secure facilities such as prisons. Also, it could provide security at intermodal transfer points, such as airport parking lots and car ferry terminals.

  7. Application of the smart portal in transportation

    Science.gov (United States)

    Kercel, Stephen W.; Baylor, Vivian M.; Dress, William B.; Hickerson, Tim W.; Jatko, William B.; Labaj, Leo E.; Muhs, Jeffrey D.; Pack, Richard M.

    1997-02-01

    Under a program sponsored by the Department of Energy, the Oak Ridge complex is developing a `Portal-of-the-Future', or `smart portal.' This is a security portal for vehicular traffic which is intended to quickly detect explosives, hidden passengers, etc. It uses several technologies, including microwaves, weigh-in-motion, digital image processing, and electroacoustic wavelet-based heartbeat detection. A novel component of particular interest is the Enclosed Space Detection System (ESDS), which detects the presence of persons hiding in a vehicle. The system operates by detecting the presence of a human ballistocardiographic signature. Each time the heart beats, it generates a small but measurable shock wave that propagates through the body. The wave, whose graph is called a ballistocardiogram, is the mechanical analog of the electrocardiograms, which is routinely used for medical diagnosis. The wave is, in turn, coupled to any surface or object with which the body is in contact. If the body is located in an enclosed space, this will result in a measurable deflection of the surface of the enclosure. Independent testing has shown ESDS to be highly reliable. The technologies used in the smart portal operate in real time and allow vehicles to be checked through the portal in much less time than would be required for human inspection. Although not originally developed for commercial transportation, the smart portal has the potential to solve several transportation problems. It could relieve congestion at international highway border crossings by reducing the time required to inspect each vehicle while increasing the level of security. It can reduce highway congestion at the entrance of secure facilities such as prisons. Also, it could provide security at intermodal transfer points, such as airport parking lots and car ferry terminals.

  8. RELIEVE: A FORTRAN 77 program for numerical and graphical processing of digital topographic maps

    International Nuclear Information System (INIS)

    Sanchez, J.J.; Gorostiza, C.

    1995-01-01

    The RELIEVE program was developed in order to its integration with the expert system SIRENAS, in the frame of the Industrial Risks Programme, within the CIEMAT center. For accomplishing this mentioned system, arose the necessity of an additional component enabled for analyzing the topography (relieve) of the territory in which the focused site is located. That is just the mission of the RELIEVE program. Basically RELIEVE analyses the digitalized data points of a determinate topographic area, around a location of interest. The program allows us estimation by numerical techniques, using IMSL library, of the deep width, and other geometrical characteristics of the valley that is involved in. Optionally RELIEVE produces also graphical outputs concerning 3D representation of topographical map, level curves, sections of interest considered in the valley, etc., by means of the DISSPLA II library, running in the IBM system of the CIEMAT. (Author) 5 refs

  9. Smart grids for smart cities: Smart energy management

    International Nuclear Information System (INIS)

    Kieny, Christophe

    2013-01-01

    Smart grids are currently a hot topic. Growing numbers of municipalities are experimenting with smart grids as the foundation for tomorrow's smart cities. And yet, end users are struggling to understand the innovative new energy distribution models just over the horizon. Our energy system is at a crossroads. And the coming years will tell us whether smart grids - whether they integrate renewable energy sources or not - will develop as a hybrid industry combining energy and IT or emerge as a full-fledged sector in and of itself. First and foremost, smart grids must be considered from a local, micro-economic standpoint, but one that also takes into account issues and interactions at the regional, national, EU, and global levels. Today, fighting climate change is a major challenge at both the national and global levels. The Kyoto Protocol and the Copenhagen Summit established a framework for crucial initiatives to combat climate change. The EU and France followed suit with their Climate and Energy Package and Grenelle de l'environnement environmental agenda. These policies set forth measures to fight climate change and to adapt to its impacts on people and the economy. France, for instance, set two basic targets to be achieved by 2020: - Make renewable energy a priority by promoting the development of energy from renewable sources to achieve the target of 23% renewables in the final energy mix. - Promote energy savings and increase energy efficiency by 20% and limit global warming to less than 2 deg. C over pre-industrial temperatures in industrialized nations by 2050 (around 1.2 deg. C above current temperatures). Tomorrow's grids will have to be smarter, which means incorporating information and communication technologies to provide the responsiveness and enhanced communication capabilities needed to meet the following challenges: - Integrating electricity from renewable sources; - Controlling demand; - Managing peak consumption; - Promoting widespread adoption of

  10. Smart sensors and systems

    CERN Document Server

    Kyung, Chong-Min; Yasuura, Hiroto; Liu, Yongpan

    2015-01-01

     This book describes for readers technology used for effective sensing of our physical world and intelligent processing techniques for sensed information, which are essential to the success of Internet of Things (IoTs).  The authors provide a multidisciplinary view of sensor technology from MEMS, biological, chemical, and electrical domains and showcase smart sensor systems in real applications including smart home, transportation, medical, environmental, agricultural, etc.  Unlike earlier books on sensors, this book will provide a “global” view on smart sensors covering abstraction levels from device, circuit, systems, and algorithms.  .

  11. Becoming a smart student

    DEFF Research Database (Denmark)

    Lundqvist, Ulla

    English abstract When teachers and students interact in everyday academic activities, some students are ascribed social roles as “smart”, which lead other students to contest these roles. Such struggles around what it means to be smart and which students come to be viewed as smart are a pertinent...... as smart and favoured by the teacher are at risk of being ostracized by peers, of encountering greater pressure for classroom performance and of suffering reduced learning opportunities. The study inspires teachers to create wiggle room for their students by becoming aware of the conventional definitions...

  12. Corporate Smart Phones

    DEFF Research Database (Denmark)

    Cavazotte, Flávia; Heloisa Lemos, Ana; Villadsen, Kaspar

    2014-01-01

    This article explores how the adoption of company sponsored smart phones inflicts upon the lives of professionals. Drawing upon qualitative interviews at a law firm in Brazil, the experiences of new smart phone users are reported upon in detail. Increased accessibility, accuracy and speed...... that negatively affected their private spheres, yet many of them paradoxically requested more efficient smart phone connectivity. The article focuses on the justifications, the different narrative strategies, employed by professionals for their conscious engagement in escalating work connectivity. It is suggested...

  13. Smart security proven practices

    CERN Document Server

    Quilter, J David

    2014-01-01

    Smart Security: Understanding and Contributing to the Business is a video presentation. Length: 68 minutes. In Smart Security: Understanding and Contributing to the Business, presenter J. David Quilter demonstrates the benefits of how a fully integrated security program increases business profits and delivers smart security practices at the same time. The presentation does away with the misconception that security is only an expense. In fact, a well-integrated security program can protect business interests, thereby enhancing productivity and net income. Quilter covers cost analysis and secu

  14. A Smart Home Center Platform Solution Based on Smart Mirror

    Directory of Open Access Journals (Sweden)

    Deng Xibo

    2017-01-01

    Full Text Available With the popularization of the concept of smart home, people have raised requirements on the experience of smart living. A smart home platform center solution is put forward in order to solve the intelligent interoperability and information integration of smart home, which enable people to have a more intelligent and convenient life experience. This platform center is achieved through the Smart Mirror. The Smart Mirror refers to a smart furniture, on the basis of the traditional concept of mirror, combining Raspberry Pi, the application of one-way mirror imaging principle, the touch-enabled design, voice and video interaction. Smart Mirror can provide a series of intelligent experience for the residents, such as controlling all the intelligent furniture through Smart Mirror; accessing and displaying the weather, time, news and other life information; monitoring the home environment; remote interconnection operation.

  15. Diagnosis and Management of Waldenström Macroglobulinemia: Mayo Stratification of Macroglobulinemia and Risk-Adapted Therapy (mSMART) Guidelines 2016.

    Science.gov (United States)

    Kapoor, Prashant; Ansell, Stephen M; Fonseca, Rafael; Chanan-Khan, Asher; Kyle, Robert A; Kumar, Shaji K; Mikhael, Joseph R; Witzig, Thomas E; Mauermann, Michelle; Dispenzieri, Angela; Ailawadhi, Sikander; Stewart, A Keith; Lacy, Martha Q; Thompson, Carrie A; Buadi, Francis K; Dingli, David; Morice, William G; Go, Ronald S; Jevremovic, Dragan; Sher, Taimur; King, Rebecca L; Braggio, Esteban; Novak, Ann; Roy, Vivek; Ketterling, Rhett P; Greipp, Patricia T; Grogan, Martha; Micallef, Ivana N; Bergsagel, P Leif; Colgan, Joseph P; Leung, Nelson; Gonsalves, Wilson I; Lin, Yi; Inwards, David J; Hayman, Suzanne R; Nowakowski, Grzegorz S; Johnston, Patrick B; Russell, Steven J; Markovic, Svetomir N; Zeldenrust, Steven R; Hwa, Yi L; Lust, John A; Porrata, Luis F; Habermann, Thomas M; Rajkumar, S Vincent; Gertz, Morie A; Reeder, Craig B

    2017-09-01

    Waldenström macroglobulinemia (WM), an IgM-associated lymphoplasmacytic lymphoma, has witnessed several practice-altering advances in recent years. With availability of a wider array of therapies, the management strategies have become increasingly complex. Our multidisciplinary team appraised studies published or presented up to December 2015 to provide consensus recommendations for a risk-adapted approach to WM, using a grading system. Waldenström macroglobulinemia remains a rare, incurable cancer, with a heterogeneous disease course. The major classes of effective agents in WM include monoclonal antibodies, alkylating agents, purine analogs, proteasome inhibitors, immunomodulatory drugs, and mammalian target of rapamycin inhibitors. However, the highest-quality evidence from rigorously conducted randomized clinical trials remains scant. Recognizing the paucity of data, we advocate participation in clinical trials, if available, at every stage of WM. Specific indications exist for initiation of therapy. Outside clinical trials, based on the synthesis of available evidence, we recommend bendamustine-rituximab as primary therapy for bulky disease, profound hematologic compromise, or constitutional symptoms attributable to WM. Dexamethasone-rituximab-cyclophosphamide is an alternative, particularly for nonbulky WM. Routine rituximab maintenance should be avoided. Plasma exchange should be promptly initiated before cytoreduction for hyperviscosity-related symptoms. Stem cell harvest for future use may be considered in first remission for patients 70 years or younger who are potential candidates for autologous stem cell transplantation. At relapse, retreatment with the original therapy is reasonable in patients with prior durable responses (time to next therapy ≥3 years) and good tolerability to previous regimen. Ibrutinib is efficacious in patients with relapsed or refractory disease harboring MYD88 L265P mutation. In the absence of neuropathy, a bortezomib

  16. Iliac Artery Stent Placement Relieves Claudication in Patients with Iliac and Superficial Femoral Artery Lesions

    International Nuclear Information System (INIS)

    Ichihashi, Shigeo; Higashiura, Wataru; Itoh, Hirofumi; Sakaguchi, Shoji; Kichikawa, Kimihiko

    2013-01-01

    Purpose. To evaluate the efficacy of iliac artery stent placement for relief of claudication in patients with both iliac and superficial femoral artery (SFA) lesions. Methods. Stent placement for only iliac artery occlusive disease was performed in 94 limbs (74 patients) with both iliac and SFA occlusive disease on the same limb. All procedures were performed because intermittent claudication did not improve after continuation of antiplatelet medication therapy and home-based exercise for 3 months. Rutherford classification was 2 in 20 limbs and 3 in 74 limbs. Patients with critical limb ischemia were excluded. Median duration of follow-up was 40 months. Primary patency rates of the iliac stent, clinical improvement rates, and risk factors for requiring additional SFA procedures were evaluated. Results. Primary patency rates of the iliac stent at 1, 3, 5, and 7 years were 97, 93, 79, and 79 %, respectively. The initial clinical improvement rate was 87 %. Continued clinical improvement rates at 1, 3, 5, and 7 years were 87, 81, 69, and 66 %, respectively. SFA Trans-Atlantic Inter-Society Consensus (TASC) II C/D lesion was a significant risk factor for requiring additional SFA procedures. Conclusion. Intermittent claudication was relieved by iliac stent placement in most patients with both iliac and SFA lesions. Thus, the indications for treatment of the SFA intended for claudicants should be evaluated after treatment of the iliac lesion.

  17. Efficacy of Trimetazidine Dihydrochloride for Relieving Chronic Tinnitus: A Randomized Double-Blind Study

    Science.gov (United States)

    Kumral, Tolgar Lütfi; Yıldırım, Güven; Berkiten, Güler; Saltürk, Ziya; Ataç, Enes; Atar, Yavuz; Uyar, Yavuz

    2016-01-01

    Objectives. To evaluate the efficacy of trimetazidine dihydrochloride as a treatment for chronic tinnitus. Methods. A total of 97 chronic tinnitus patients were evaluated in this randomized, prospective, double-blind, placebo-controlled trial. After assessing for eligibility, 82 patients were randomly assigned into placebo or trimetazidine groups according to the medication. The trimetazidine group received 20×3 mg/day per oral trimetazidine dihydrochloride and the placebo group received 20×3 mg/day per oral placebo for 3 months. Tinnitus handicap inventory (THI), visual analogue scale (VAS) questionnaires and audiometric results were used to determine the effectiveness of trimetazidine treatment. Results. The study group comprised 82 tinnitus subjects, 42 (51%) of whom received trimetazidine dihydrochloride and 40 (49%) who received placebo. There was no significant difference between placebo and trimetazidine groups in THI grade and VAS (both pre- and posttreatment scores) (P>0.05) and no significant improvement was observed in subjective loudness score in either group (P>0.05). Additionally there was no significant difference between groups in pre- and posttreatment pure tone hearing thresholds at all measured frequencies (P>0.05). Conclusion. Trimetazidine dihydrochloride therapy was ineffective for relieving chronic tinnitus. PMID:27230273

  18. Smart City project

    KAUST Repository

    Al Harbi, Ayman

    2018-01-01

    A 'smart city' is an urban region that is highly advanced in terms of overall infrastructure, sustainable real estate, communications and market viability. It is a city where information technology is the principal infrastructure and the basis

  19. Test Your Sodium Smarts

    Science.gov (United States)

    ... You may be surprised to learn how much sodium is in many foods. Sodium, including sodium chloride ... foods with little or no salt. Test your sodium smarts by answering these 10 questions about which ...

  20. Smart Location Mapping

    Science.gov (United States)

    The Smart Location Database, Access to Jobs and Workers via Transit, and National Walkability Index tools can help assess indicators related to the built environment, transit accessibility, and walkability.

  1. Guest Editorial - Smart materials

    Czech Academy of Sciences Publication Activity Database

    Barber, Z. H.; Clyne, T. W.; Šittner, Petr

    2014-01-01

    Roč. 30, 13a (2014), s. 1515-1516 ISSN 0267-0836 Institutional support: RVO:68378271 Keywords : smart materials * shape memory effect (SME) Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.995, year: 2014

  2. Smart Book Charts

    Science.gov (United States)

    Chinnapongse, Ronald L.

    2015-01-01

    Smart book charts for TPSM: Heatshield for Extreme Entry Environment Technology (HEEET), Conformal Ablative TPS (CA-TPS), 3D Woven Multifunctional Ablative TPS (3D MAT), and Adaptable, Deployable, Entry and Placement Technology (ADEPT).

  3. Becoming a Smart Student

    DEFF Research Database (Denmark)

    Lundqvist, Ulla

    identification” and “participation framework”. Methodologically, the study is based on three years of linguistic ethnographic fieldwork in a public primary school in Copenhagen and with students and their families. This study documents -in broad ethnographic scope and interactional detail -how smart student...... through future explorations of children’s academic trajectories in and out of school, and on how those trajectories often become linked to the trajectories of siblings, vis-à-vis institutional conceptions of smartness.......When teachers and students interact in everyday academic activities, some students are ascribed social roles as “smart”, which lead other students to contest these roles. Such struggles around what it means to be smart and which students come to be viewed as smart are a pertinent problem...

  4. Technology Roadmaps: Smart Grids

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The development of Technology Roadmaps: Smart Grids -- which the IEA defines as an electricity network that uses digital and other advanced technologies to monitor and manage the transport of electricity from all generation sources to meet the varying electricity demands of end users -- is essential if the global community is to achieve shared goals for energy security, economic development and climate change mitigation. Unfortunately, existing misunderstandings of exactly what smart grids are and the physical and institutional complexity of electricity systems make it difficult to implement smart grids on the scale that is needed. This roadmap sets out specific steps needed over the coming years to achieve milestones that will allow smart grids to deliver a clean energy future.

  5. SMART : de ontwerplogica

    NARCIS (Netherlands)

    Zeiler, W.; Jelsma, J.; Kamphuis, I.G.

    2005-01-01

    Het vakgebied van de regeltechniek is zeer geschikt om ontwikkelingen vanuit de computertechnologie toe te passen. Zo zijn er systemen met regelalgoritmes gebaseerd op technieken zoals neurale netwerken, fuzzy logic, genetische algoritmes en kennissystemen gebouwd. Binnen het onderzoeksproject SMART

  6. Ammonia chemistry at SMART

    International Nuclear Information System (INIS)

    Na, J. W.; Seong, G. W.; Lee, E. H.; Kim, W. C.; Choi, B. S.; Kim, J. P.; Lee, D. J.

    1999-01-01

    Ammonia is used as the pH control agent of primary water at SMART (System-integrated Modular Advanced ReacTor). Some of this ammonia is decomposed to hydrogen and nitrogen by radiation in the reactor core. The produced hydrogen gas is used for the removal of dissolved oxygen in the coolant. Some of nitrogen gas in pressurizer is dissolved into the primary water. Because ammonia, hydrogen and nitrogen which is produced by ammonia radiolysis are exist in the coolant at SMART, ammonia chemistry at SMART is different with lithium-boron chemistry at commercial PWR. In this study, the pH characteristics of ammonia and the solubility characteristics of hydrogen and nytrogen were analyzed for the management of primary water chemistry at SMART

  7. Controlling smart grid adaptivity

    NARCIS (Netherlands)

    Toersche, Hermen; Nykamp, Stefan; Molderink, Albert; Hurink, Johann L.; Smit, Gerardus Johannes Maria

    2012-01-01

    Methods are discussed for planning oriented smart grid control to cope with scenarios with limited predictability, supporting an increasing penetration of stochastic renewable resources. The performance of these methods is evaluated with simulations using measured wind generation and consumption

  8. Home, Smart Home

    DEFF Research Database (Denmark)

    Hansen, Ellen Kathrine; Olesen, Gitte Gylling Hammershøj; Mullins, Michael

    2013-01-01

    The article places focus on how smart technologies integrated in a one family- home and particular the window offer unique challenges and opportunities for designing buildings with the best possible environments for people and nature. Toward an interdisciplinary approach, we address the interaction...... between daylight defined in technical terms and daylight defined in aesthetic, architectural terms. Through field-tests of a Danish carbon-neutral home and an analysis of five key design parameters, we explore the contradictions and potentials in smart buildings, using the smart window as example of how...... to the energy design is central. The study illuminates an approach of the design of smart houses as living organisms by connecting technology with the needs of the occupants with the power and beauty of daylight....

  9. The Smart Factory

    DEFF Research Database (Denmark)

    Radziwon, Agnieszka; Bilberg, Arne; Bogers, Marcel

    2014-01-01

    Nowadays we live in a world, which a decade ago would only be described in the science fiction literature. More and more things become smart and both scientists and engineers strive for developing not only new and innovative devices, but also homes, factories, or even cities. Despite of continuous...... development, many of those concepts are still being just a vision of the future, which still needs a lot of effort to become true. This paper reviews the usage of adjective smart in respect to technology and with a special emphasis on the smart factory concept placement among contemporary studies. Due...... to a lack of a consensus of common understanding of this term, a unified definition is proposed. The conceptualization will not only refer to various smart factory visions reported in the literature, but also link the crucial characteristics of this emerging manufacturing concept to usual manufacturing...

  10. Acupuncture and Auricular Acupressure in Relieving Menopausal Hot Flashes of Bilaterally Ovariectomized Chinese Women: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Jue Zhou

    2011-01-01

    Full Text Available The objective of this study is to explore the effects of acupuncture and auricular acupressure in relieving menopausal hot flashes of bilaterally ovariectomized Chinese women. Between May 2006 and March 2008, 46 bilaterally ovariectomized Chinese women were randomized into an acupuncture and auricular acupressure group (n = 21 and a hormone replacement therapy (HRT group (Tibolone, n = 25. Each patient was given a standard daily log and was required to record the frequency and severity of hot flashes and side effects of the treatment felt daily, from 1 week before the treatment started to the fourth week after the treatment ended. The serum levels of follicle stimulating hormone (FSH, LH and E2 were detected before and after the treatment. After the treatment and the follow-up, both the severity and frequency of hot flashes in the two groups were relieved significantly when compared with pre-treatment (P   .05, while after the follow-up, the severity of hot flashes in the HRT group was alleviated more. After the treatment and the follow-up, the frequency of menopausal hot flashes in the HRT group was reduced more (P <  .05. After treatment, the levels of FSH decreased significantly and the levels of E2 increased significantly in both groups (P <  .05, and they changed more in the HRT group (P <  .05. Acupuncture and auricular acupressure can be used as alternative treatments to relieve menopausal hot flashes for those bilaterally ovariectomized women who are unable or unwilling to receive HRT.

  11. Smart Home Hacking

    OpenAIRE

    Kodra, Suela

    2016-01-01

    Smart Home is an intelligent home equipped with devices and communications systems that enables the residents to connect and control their home appliances and systems. This technology has changed the way a consumer interacts with his home, enabling more control and convenience. Another advantage of this technology is the positive impact it has on savings on energy and other resources. However, despite the consumer's excitement about smart home, security and privacy have shown to be the strong...

  12. Smart bomb for cancer

    International Nuclear Information System (INIS)

    Karagiannis, Tom

    2006-01-01

    recognise cell-surface receptors on cancer cells that are either not found on healthy cells or that are found on healthy cells but are expressed at much lower levels. The main focus of our research in the Molecular Radiation Biology Laboratory at the Peter MacCallum Cancer Centre is to develop a type of monoclonal antibody-based cancer therapy referred to as radio-immunotherapy. In its simplest form, radio-immunotherapy involves the use of a monoclonal antibody to deliver a radioactive atom specifically to cancer cells. The idea is that targeting the radiation specifically to cancer cells using a monoclonal antibody will deliver a sufficient radiation dose to kill diseased cells, while minimising the damage to healthy surrounding tissue. To date, the monoclonal antibodies ibritumomab tiuxetan (Zevalin) and tositumomab (Bexxar), which are labelled with a radioactive atom, have been approved by the US Food and Drug Administration for radio-immunotherapy of non-Hodgkin's lymphoma. Our strategy is a more complex multi-step approach. It involves targeting the radioactive atom not only to cancer cells but also to the DNA of those cells. Our smart molecular bombs that consist of three different parts. The first part is a special type of radioactive atom known as an Auger electron-emitting isotope, which is used to destroy the cancer cell. The radioactive atom is then linked to a small drug molecule that binds very tightly to DNA. This DNA-binding drug delivers the radiation in close proximity to the DNA so that the radioactive atom can kill the cancer cell by breaking the genetic material. To make our potential therapy specific for cancer cells we then chemically link the radiation-containing DNA-binding drug to an anti-cancer monoclonal antibody

  13. SMART performance analysis methodology

    International Nuclear Information System (INIS)

    Lim, H. S.; Kim, H. C.; Lee, D. J.

    2001-04-01

    To ensure the required and desired operation over the plant lifetime, the performance analysis for the SMART NSSS design is done by means of the specified analysis methodologies for the performance related design basis events(PRDBE). The PRDBE is an occurrence(event) that shall be accommodated in the design of the plant and whose consequence would be no more severe than normal service effects of the plant equipment. The performance analysis methodology which systematizes the methods and procedures to analyze the PRDBEs is as follows. Based on the operation mode suitable to the characteristics of the SMART NSSS, the corresponding PRDBEs and allowable range of process parameters for these events are deduced. With the developed control logic for each operation mode, the system thermalhydraulics are analyzed for the chosen PRDBEs using the system analysis code. Particularly, because of different system characteristics of SMART from the existing commercial nuclear power plants, the operation mode, PRDBEs, control logic, and analysis code should be consistent with the SMART design. This report presents the categories of the PRDBEs chosen based on each operation mode and the transition among these and the acceptance criteria for each PRDBE. It also includes the analysis methods and procedures for each PRDBE and the concept of the control logic for each operation mode. Therefore this report in which the overall details for SMART performance analysis are specified based on the current SMART design, would be utilized as a guide for the detailed performance analysis

  14. Smart acquisition EELS

    International Nuclear Information System (INIS)

    Sader, Kasim; Schaffer, Bernhard; Vaughan, Gareth; Brydson, Rik; Brown, Andy; Bleloch, Andrew

    2010-01-01

    We have developed a novel acquisition methodology for the recording of electron energy loss spectra (EELS) using a scanning transmission electron microscope (STEM): 'Smart Acquisition'. Smart Acquisition allows the independent control of probe scanning procedures and the simultaneous acquisition of analytical signals such as EELS. The original motivation for this work arose from the need to control the electron dose experienced by beam-sensitive specimens whilst maintaining a sufficiently high signal-to-noise ratio in the EEL signal for the extraction of useful analytical information (such as energy loss near edge spectral features) from relatively undamaged areas. We have developed a flexible acquisition framework which separates beam position data input, beam positioning, and EELS acquisition. In this paper we demonstrate the effectiveness of this technique on beam-sensitive thin films of amorphous aluminium trifluoride. Smart Acquisition has been used to expose lines to the electron beam, followed by analysis of the structures created by line-integrating EELS acquisitions, and the results are compared to those derived from a standard EELS linescan. High angle annular dark-field images show clear reductions in damage for the Smart Acquisition areas compared to the conventional linescan, and the Smart Acquisition low loss EEL spectra are more representative of the undamaged material than those derived using a conventional linescan. Atomically resolved EELS of all four elements of CaNdTiO show the high resolution capabilities of Smart Acquisition.

  15. Smart acquisition EELS

    Energy Technology Data Exchange (ETDEWEB)

    Sader, Kasim, E-mail: k.sader@leeds.ac.uk [SuperSTEM, J block, Daresbury Laboratory, Warrington, Cheshire, WA4 4AD (United Kingdom); Institute for Materials Research, University of Leeds, LS2 9JT (United Kingdom); Schaffer, Bernhard [SuperSTEM, J block, Daresbury Laboratory, Warrington, Cheshire, WA4 4AD (United Kingdom); Department of Physics and Astronomy, University of Glasgow (United Kingdom); Vaughan, Gareth [Institute for Materials Research, University of Leeds, LS2 9JT (United Kingdom); Brydson, Rik [SuperSTEM, J block, Daresbury Laboratory, Warrington, Cheshire, WA4 4AD (United Kingdom); Institute for Materials Research, University of Leeds, LS2 9JT (United Kingdom); Brown, Andy [Institute for Materials Research, University of Leeds, LS2 9JT (United Kingdom); Bleloch, Andrew [SuperSTEM, J block, Daresbury Laboratory, Warrington, Cheshire, WA4 4AD (United Kingdom); Department of Engineering, University of Liverpool, Liverpool (United Kingdom)

    2010-07-15

    We have developed a novel acquisition methodology for the recording of electron energy loss spectra (EELS) using a scanning transmission electron microscope (STEM): 'Smart Acquisition'. Smart Acquisition allows the independent control of probe scanning procedures and the simultaneous acquisition of analytical signals such as EELS. The original motivation for this work arose from the need to control the electron dose experienced by beam-sensitive specimens whilst maintaining a sufficiently high signal-to-noise ratio in the EEL signal for the extraction of useful analytical information (such as energy loss near edge spectral features) from relatively undamaged areas. We have developed a flexible acquisition framework which separates beam position data input, beam positioning, and EELS acquisition. In this paper we demonstrate the effectiveness of this technique on beam-sensitive thin films of amorphous aluminium trifluoride. Smart Acquisition has been used to expose lines to the electron beam, followed by analysis of the structures created by line-integrating EELS acquisitions, and the results are compared to those derived from a standard EELS linescan. High angle annular dark-field images show clear reductions in damage for the Smart Acquisition areas compared to the conventional linescan, and the Smart Acquisition low loss EEL spectra are more representative of the undamaged material than those derived using a conventional linescan. Atomically resolved EELS of all four elements of CaNdTiO show the high resolution capabilities of Smart Acquisition.

  16. The Smart Energy System

    DEFF Research Database (Denmark)

    Jurowetzki, Roman; Dyrelund, Anders; Hummelmose, Lars

    Copenhagen Cleantech Cluster has launched a new report, which provides an overview of Danish competencies relating to smart energy systems. The report, which is based on a questionnaire answered by almost 200 companies working with smart energy as well as a number of expert interviews, focuses on...... production, large scale solar heat, fuel cells, heat storage, waste incineration, among others, the report draws a picture of Denmark as a research and development hub for smart energy system solutions.......Copenhagen Cleantech Cluster has launched a new report, which provides an overview of Danish competencies relating to smart energy systems. The report, which is based on a questionnaire answered by almost 200 companies working with smart energy as well as a number of expert interviews, focuses...... on the synergies which are obtained through integration of the district heating and district cooling, gas, and electricity grid into a single smart energy system. Besides documenting the technology and innovation strengths that Danish companies possess particularly relating to wind, district heating, CHP...

  17. Smart Grid Integration Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Troxell, Wade [Colorado State Univ., Fort Collins, CO (United States)

    2011-12-22

    The initial federal funding for the Colorado State University Smart Grid Integration Laboratory is through a Congressionally Directed Project (CDP), DE-OE0000070 Smart Grid Integration Laboratory. The original program requested in three one-year increments for staff acquisition, curriculum development, and instrumentation all which will benefit the Laboratory. This report focuses on the initial phase of staff acquisition which was directed and administered by DOE NETL/ West Virginia under Project Officer Tom George. Using this CDP funding, we have developed the leadership and intellectual capacity for the SGIC. This was accomplished by investing (hiring) a core team of Smart Grid Systems engineering faculty focused on education, research, and innovation of a secure and smart grid infrastructure. The Smart Grid Integration Laboratory will be housed with the separately funded Integrid Laboratory as part of CSU's overall Smart Grid Integration Center (SGIC). The period of performance of this grant was 10/1/2009 to 9/30/2011 which included one no cost extension due to time delays in faculty hiring. The Smart Grid Integration Laboratory's focus is to build foundations to help graduate and undergraduates acquire systems engineering knowledge; conduct innovative research; and team externally with grid smart organizations. Using the results of the separately funded Smart Grid Workforce Education Workshop (May 2009) sponsored by the City of Fort Collins, Northern Colorado Clean Energy Cluster, Colorado State University Continuing Education, Spirae, and Siemens has been used to guide the hiring of faculty, program curriculum and education plan. This project develops faculty leaders with the intellectual capacity to inspire its students to become leaders that substantially contribute to the development and maintenance of Smart Grid infrastructure through topics such as: (1) Distributed energy systems modeling and control; (2) Energy and power conversion; (3

  18. From Smart Metering to Smart Grid

    Science.gov (United States)

    Kukuča, Peter; Chrapčiak, Igor

    2016-06-01

    The paper deals with evaluation of measurements in electrical distribution systems aimed at better use of data provided by Smart Metering systems. The influence of individual components of apparent power on the power loss is calculated and results of measurements under real conditions are presented. The significance of difference between the traditional and the complex evaluation of the electricity consumption efficiency by means of different definitions of the power factor is illustrated.

  19. Towards the Smart World. Smart Platform: Infrastructure and Analytics

    CSIR Research Space (South Africa)

    Velthausz, D

    2012-10-01

    Full Text Available In this presentation the author outlines the 'smart world' concept and how technology (smart infrastructure, analytics) can foster smarter cities, smarter regions and a smarter world....

  20. SMART SUSTAINABLE ISLANDS VS SMART SUSTAINABLE CITIES

    Directory of Open Access Journals (Sweden)

    D. N. Pantazis

    2017-09-01

    Full Text Available This paper has several aims: a the presentation of a critical analysis of the terms “smart sustainable cities” and “smart sustainable islands” b the presentation of a number of principles towards to the development methodological framework of concepts and actions, in a form of a manual and actions guide, for the smartification and sustainability of islands. This kind of master plan is divided in thematic sectors (key factors which concern the insular municipalities c the creation of an island’s smartification and sustainability index d the first steps towards the creation of a portal for the presentation of our smartification actions manual, together with relative resources, smart applications examples, and, in the near future the first results of our index application in a number of Greek islands and e the presentation of some proposals of possible actions towards their sustainable development and smartification for the municipalities - islands of Paros and Antiparos in Greece, as case studies.

  1. Smart Demand Response Based on Smart Homes

    Directory of Open Access Journals (Sweden)

    Jingang Lai

    2015-01-01

    Full Text Available Smart homes (SHs are crucial parts for demand response management (DRM of smart grid (SG. The aim of SHs based demand response (DR is to provide a flexible two-way energy feedback whilst (or shortly after the consumption occurs. It can potentially persuade end-users to achieve energy saving and cooperate with the electricity producer or supplier to maintain balance between the electricity supply and demand through the method of peak shaving and valley filling. However, existing solutions are challenged by the lack of consideration between the wide application of fiber power cable to the home (FPCTTH and related users’ behaviors. Based on the new network infrastructure, the design and development of smart DR systems based on SHs are related with not only functionalities as security, convenience, and comfort, but also energy savings. A new multirouting protocol based on Kruskal’s algorithm is designed for the reliability and safety of the SHs distribution network. The benefits of FPCTTH-based SHs are summarized at the end of the paper.

  2. Benchmarking the ERG valve tip and MRI Interventions Smart Flow neurocatheter convection-enhanced delivery system's performance in a gel model of the brain: employing infusion protocols proposed for gene therapy for Parkinson's disease

    Science.gov (United States)

    Sillay, Karl; Schomberg, Dominic; Hinchman, Angelica; Kumbier, Lauren; Ross, Chris; Kubota, Ken; Brodsky, Ethan; Miranpuri, Gurwattan

    2012-04-01

    Convection-enhanced delivery (CED) is an advanced infusion technique used to deliver therapeutic agents into the brain. CED has shown promise in recent clinical trials. Independent verification of published parameters is warranted with benchmark testing of published parameters in applicable models such as gel phantoms, ex vivo tissue and in vivo non-human animal models to effectively inform planned and future clinical therapies. In the current study, specific performance characteristics of two CED infusion catheter systems, such as backflow, infusion cloud morphology, volume of distribution (mm3) versus the infused volume (mm3) (Vd/Vi) ratios, rate of infusion (µl min-1) and pressure (mmHg), were examined to ensure published performance standards for the ERG valve-tip (VT) catheter. We tested the hypothesis that the ERG VT catheter with an infusion protocol of a steady 1 µl min-1 functionality is comparable to the newly FDA approved MRI Interventions Smart Flow (SF) catheter with the UCSF infusion protocol in an agarose gel model. In the gel phantom models, no significant difference was found in performance parameters between the VT and SF catheter. We report, for the first time, such benchmark characteristics in CED between these two otherwise similar single-end port VT with stylet and end-port non-stylet infusion systems. Results of the current study in agarose gel models suggest that the performance of the VT catheter is comparable to the SF catheter and warrants further investigation as a tool in the armamentarium of CED techniques for eventual clinical use and application.

  3. [Smart therapeutics based on synthetic gene circuits].

    Science.gov (United States)

    Peng, Shuguang; Xie, Zhen

    2017-03-25

    Synthetic biology has an important impact on biology research since its birth. Applying the thought and methods that reference from electrical engineering, synthetic biology uncovers many regulatory mechanisms of life systems, transforms and expands a series of biological components. Therefore, it brings a wide range of biomedical applications, including providing new ideas for disease diagnosis and treatment. This review describes the latest advances in the field of disease diagnosis and therapy based on mammalian cell or bacterial synthetic gene circuits, and provides new ideas for future smart therapy design.

  4. Less Smart More City

    Directory of Open Access Journals (Sweden)

    Rocco Papa

    2015-07-01

    Full Text Available Smart is an expression used in recent years in science, and it refers to someone or something that shows a lively intelligence, with a quick learning curve and a fast response to external stimuli. The present scenario is dominated by the accelerated technological development that involves every aspect of life, enhancing the everyday tools through the use of information and digital processing: everything is smart, even cities. But when you pair the term smart to a complex organism such as the city the significance of the two together is open to a variety of interpretations, as shown by the vast and varied landscape of definitions that have occurred in recent years. Our contribution presents the results of research aimed at analyzing and interpreting this fragmented scene mainly, but not exclusively, through lexical analysis, applied to a textual corpus of 156 definitions of smart city. In particular, the study identified the main groups of stakeholders that have taken part in the debate, and investigated the differences and convergences that can be detected: Academic, Institutional, and Business worlds. It is undeniable that the term smart has been a veritable media vehicle that, on the one hand brought to the center of the discussion the issue of the city, of increasing strategic importance for the major challenges that humanity is going to face,  and on the other has been a fertile ground on which to pour the interests of different groups and individuals. In a nutshell we can say that from the analysis the different approaches that each group has used and supported emerge clearly and another, alarming, consideration occurs: of the smart part of “Smart City” we clearly grasp the tools useful to the each group of stakeholders, and of the city part, as a collective aspiration, there is often little or nothing.

  5. Reversible hemispheric hypoperfusion in two cases of SMART syndrome.

    Science.gov (United States)

    Wai, Karmen; Balabanski, Anna; Chia, Nicholas; Kleinig, Timothy

    2017-09-01

    Stroke-like migraine attacks after radiation therapy (SMART) syndrome manifests as prolonged episodes of cortical dysfunction, years after cranial irradiation. We present two cases demonstrating reversible hemispheric hypoperfusion. Case 1 presented with left hemispheric symptoms following previous similar episodes. CT perfusion (CTP) demonstrated reversible hemispheric hypoperfusion; subsequent investigations were consistent with SMART syndrome. Case 2 presented following the third episode of a hemispheric syndrome with near-identical CTP abnormalities. L-arginine was administered with rapid reversal of clinical and CTP abnormalities. We conclude that SMART syndrome may demonstrate significant hypoperfusion on hyperacute CTP without subsequent infarction. Impaired cerebrovascular autoregulation probably contributes to cortical dysfunction in SMART syndrome. L-arginine warrants investigation as a potential treatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Market Acceptance of Smart Growth

    Science.gov (United States)

    This report finds that smart growth developments enjoy market acceptance because of stability in prices over time. Housing resales in smart growth developments often have greater appreciation than their conventional suburban counterparts.

  7. The Future of Smart Cards.

    Science.gov (United States)

    Fickes, Michael

    2000-01-01

    Discusses the evolution of smart cards from digital signatures and other innovations into the realm of magnetic-stripe cards to expand their applications. Examples of magnetic-strip smart card usage are examined. (GR)

  8. State and Substate Estimates of Nonmedical Use of Prescription Pain Relievers

    Science.gov (United States)

    ... with other local area data to enhance statistical power and analytic capability. 10 Delete Template National, Regional, and State Estimates In this section, estimates of past year nonmedical use of prescription pain relievers among people aged 12 or older are ...

  9. A smart upconversion-based light-triggered polymer for synergetic chemo-photodynamic therapy and dual-modal MR/UCL imaging.

    Science.gov (United States)

    Du, Bin; Han, Shuping; Zhao, Feifei; Lim, Kok Hwa; Xi, Hongwei; Su, Xiangjie; Yao, Hanchun; Zhou, Jie

    2016-10-01

    We have developed a novel nanocomposite to achieve effective therapy and live surveillance of tumor tissue. In this study, fullerene (C 60 ) with iron oxide (Fe 3 O 4 ) nanoparticles and upconversion nanophosphors (UCNPs) was loaded into N-succinyl-N'-4-(2-nitrobenzyloxy)-succinyl-chitosan micelles (SNSC) with good biocompatibility. In addition, hydrophobic anticancer drug docetaxel (DTX) was also loaded into the nanocomposites. The experiments conducted in vitro and in vivo demonstrated that C 60 /Fe 3 O 4 -UCNPs@DTX@SNSC can act synergistically to kill tumor cells by releasing chemotherapy drugs at specific target site as well as generating reactive oxygen using 980nm. In addition, it can also be used for non-invasive deep magnetic resonance and upconversion fluorescence dual-mode imaging. The results indicated that this system provided an efficient method to surmount the drawback of UV or visible light-responsive polymeric systems for controlled drug release and generated reactive oxygen in deep tissues and ultimately realized the integration of dual-modal imaging and treatment. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Adding Concurrency to Smart Contracts

    OpenAIRE

    Dickerson, Thomas; Gazzillo, Paul; Herlihy, Maurice; Koskinen, Eric

    2017-01-01

    Modern cryptocurrency systems, such as Ethereum, permit complex financial transactions through scripts called smart contracts. These smart contracts are executed many, many times, always without real concurrency. First, all smart contracts are serially executed by miners before appending them to the blockchain. Later, those contracts are serially re-executed by validators to verify that the smart contracts were executed correctly by miners. Serial execution limits system throughput and fails ...

  11. Wireless Smart Systems Beyond RFID

    OpenAIRE

    Vermesan, Ovidiu

    2008-01-01

    It is expected that in the coming 20 years the IoT will be pervasive, and ubiquitous: smart devices, embedded in smart materials, will work in synergy to improve the quality of our lives. In this context wireless smart systems will play an essential role that is far beyond the ID information that is part of RFID devices today. Wireless Smart Systems Beyond RFID

  12. Smart Distribution Systems

    Directory of Open Access Journals (Sweden)

    Yazhou Jiang

    2016-04-01

    Full Text Available The increasing importance of system reliability and resilience is changing the way distribution systems are planned and operated. To achieve a distribution system self-healing against power outages, emerging technologies and devices, such as remote-controlled switches (RCSs and smart meters, are being deployed. The higher level of automation is transforming traditional distribution systems into the smart distribution systems (SDSs of the future. The availability of data and remote control capability in SDSs provides distribution operators with an opportunity to optimize system operation and control. In this paper, the development of SDSs and resulting benefits of enhanced system capabilities are discussed. A comprehensive survey is conducted on the state-of-the-art applications of RCSs and smart meters in SDSs. Specifically, a new method, called Temporal Causal Diagram (TCD, is used to incorporate outage notifications from smart meters for enhanced outage management. To fully utilize the fast operation of RCSs, the spanning tree search algorithm is used to develop service restoration strategies. Optimal placement of RCSs and the resulting enhancement of system reliability are discussed. Distribution system resilience with respect to extreme events is presented. Test cases are used to demonstrate the benefit of SDSs. Active management of distributed generators (DGs is introduced. Future research in a smart distribution environment is proposed.

  13. NSTAR Smart Grid Pilot

    Energy Technology Data Exchange (ETDEWEB)

    Rabari, Anil [NSTAR Electric, Manchester, NH (United States); Fadipe, Oloruntomi [NSTAR Electric, Manchester, NH (United States)

    2014-03-31

    NSTAR Electric & Gas Corporation (“the Company”, or “NSTAR”) developed and implemented a Smart Grid pilot program beginning in 2010 to demonstrate the viability of leveraging existing automated meter reading (“AMR”) deployments to provide much of the Smart Grid functionality of advanced metering infrastructure (“AMI”), but without the large capital investment that AMI rollouts typically entail. In particular, a central objective of the Smart Energy Pilot was to enable residential dynamic pricing (time-of-use “TOU” and critical peak rates and rebates) and two-way direct load control (“DLC”) by continually capturing AMR meter data transmissions and communicating through customer-sited broadband connections in conjunction with a standardsbased home area network (“HAN”). The pilot was supported by the U.S. Department of Energy’s (“DOE”) through the Smart Grid Demonstration program. NSTAR was very pleased to not only receive the funding support from DOE, but the guidance and support of the DOE throughout the pilot. NSTAR is also pleased to report to the DOE that it was able to execute and deliver a successful pilot on time and on budget. NSTAR looks for future opportunities to work with the DOE and others in future smart grid projects.

  14. Increase of resistance to cracking on stress relieving of hardened steel

    International Nuclear Information System (INIS)

    Velichko, V.V.; Zabil'skij, V.V.; Mikheev, G.M.

    1995-01-01

    Regularities of increase of resistance to cracking during stress relieving of hardened low-alloyed steels were studied, using complex of methods. Effect of carbon, stress concentrator radius, duration and temperature of stress relieving was studies in particular. Results of investigating kinetics of change of physicomechanical properties, hydrogen desorption from hardened specimens showed, that increase of resistance to cracking was caused by desorption from grain boundaries of diffusion-mobile hydrogen, formed during hardening. 18 refs., 8 figs

  15. Smart meter incorporating UWB technology

    NARCIS (Netherlands)

    Khan, T.A.; Khan, A.B.; Babar, M.; Taj, T.A.

    2014-01-01

    Smart Meter is a key element in the evolving concept of Smart Grid, which plays an important role in interaction between the consumer and the supplier. In general, the smart meter is an intelligent digital energy meter that measures the consumption of electrical energy and provides other additional

  16. Smart metering design and applications

    CERN Document Server

    Weranga, K S K; Chandima, D P

    2013-01-01

    Taking into account the present day trends and the requirements, this Brief focuses on smart metering of electricity for next generation energy efficiency and conservation. The contents include discussions on the smart metering concepts and existing technologies and systems as well as design and implementation of smart metering schemes together with detailed examples.

  17. The Science of Smart Materials

    Science.gov (United States)

    Boohan, Richard

    2011-01-01

    Over the last few decades, smart materials have become increasingly important in the design of products. Essentially, a smart material is one that has been designed to respond to a stimulus, such as a change in temperature or magnetic field, in a particular and useful way. This article looks at a range of smart materials that are relatively…

  18. What is a smart grid?

    NARCIS (Netherlands)

    Kumar, A.

    2017-01-01

    The Indian Smart Grid Forum defines a smart grid as "a power system capable of two-way communication between all the entities of the network-generation, transmission, distribution and the consumers". Like most work on smart grids, this view is also mainly technical. This paper aims to progress the

  19. Electromagnetic Interference in Smart Grids

    NARCIS (Netherlands)

    Leferink, Frank; Keyer, Cees

    2017-01-01

    The increasing conducted interference caused by modern electronic equipment is causing more problems for electronic, or static, energy meters. If equipped with a communication link they are called smart meter. Because the smart meter is a key device in smart grids, any deviation has huge impact on

  20. Smart TV and data protection

    NARCIS (Netherlands)

    van Breda, B.; van Eijk, N.; Irion, K.; McGonagle, T.; van Voorst, S.

    2016-01-01

    What is smart TV? How does smart TV compare with other forms of audiovisual media? What regulatory frameworks govern smart TV? What guidance can be found in selected country-specific case studies? What are the dangers associated with the collection, storage and processing of private user information

  1. The influence of the ion implantation temperature and the dose rate on smart-cut in GaAs

    International Nuclear Information System (INIS)

    Webb, M.; Jeynes, C.; Gwilliam, R.; Too, P.; Kozanecki, A.; Domagala, J.; Royle, A.; Sealy, B.

    2005-01-01

    The temperature and dose rate dependence of the smart-cut process in GaAs have been investigated in this paper. The distribution of hydrogen and the implantation damage in the samples were studied by ion beam analysis and X-ray diffraction. It was found that at higher temperatures, hydrogen is mobile in the lattice and can rearrange into the platelets, microcracks and bubbles which are present in blistered material, thus relieving the strain in the lattice. The dose rate was also found to be significant for the smart-cut process, as blistering and exfoliation are inhibited at low dose rates

  2. Realisering af Smart City/Smart House i Nordjylland

    DEFF Research Database (Denmark)

    Lindgren, Peter; Saghaug, Kristin Margrethe

    2008-01-01

    beskriver tankerne, visionerne og perspektiverne i forhold til at realisere Smart House-konceptet i Region Nordjylland. Smart House-tankerne er baseret på at bygge smarte huse og smarte byggekomponenter til fremtidens brugere, hvor den nyeste teknologi indenfor byggematerialer kombineres med nye værdier....... Formålet med Smart House Nordjylland er at flytte byggeindustriens og forskernes fokus fra en indbyrdes konkurrence lokalt til et udviklende innovationssamarbejde, som sigter mod det globale marked. På denne måde kan regionen skabe et udstillingsvindue indenfor fremtidens byggeri gennem en interaktion...

  3. SmartCityWare

    DEFF Research Database (Denmark)

    Mohamed, Nader; Al-Jaroodi, Jameela; Jawhar, Imad

    2017-01-01

    Smart cities are becoming a reality. Various aspects of modern cities are being automated and integrated with information and communication technologies to achieve higher functionality, optimized resources utilization, and management, and improved quality of life for the residents. Smart cities...... rely heavily on utilizing various software, hardware, and communication technologies to improve the operations in areas, such as healthcare, transportation, energy, education, logistics, and many others, while reducing costs and resources consumption. One of the promising technologies to support...... technology is Fog Computing, which extends the traditional Cloud Computing paradigm to the edge of the network to enable localized and real-time support for operating-enhanced smart city services. However, proper integration and efficient utilization of CoT and Fog Computing is not an easy task. This paper...

  4. SMART product innovation

    DEFF Research Database (Denmark)

    Cramer-Petersen, Claus L.; Ahmed-Kristensen, Saeema; Li, Xuemeng

    2016-01-01

    Among the inspirations for the SMART process is “design to customer value,” where products are modified based on a thorough understanding of customers that allows product developers to eliminate features that do not affect customer satisfaction while including only the elements and functionality...... that customers really appreciate. The SMART process includes methods to understand product value for the customer and the user; analyse the cost of components and processes; combine customer value and cost reduction potentials into feasible, high-value concepts; and generate prototypes that can be tested...... with users and customers....

  5. Experimental allergic encephalomyelitis: peculiarities of pain-relieving therapy and place of anticonvulsants as analgetics

    Directory of Open Access Journals (Sweden)

    Nefyodov O.O.

    2015-11-01

    Full Text Available Multiple sclerosis (MS is the most common demyelinating disease affecting mainly young people of the working age (16-45 years and quickly leading to disability. Available data constitute that up to 80% of MS patients suffer from pain at different disease periods. Pain management and the analgesic drug choice in MS patients may be difficult. Anticonvulsant drugs possess an analgesic activity and are widely used in patients presenting painful neuropathic symptoms. Based on that, we aimed to investigate the nociceptive potential changes as well as the research-oriented behavior using the "open field" test in rat. An experimental animal equivalent of multiple sclerosis has been modeled, based on the methylprednisolone (M administration. Animals were also administered anticonvulsants (carbamazepine, topiramate, sodium volproat, pregabalin and gabapentin. The stu­dy showed advantages of gabapentin and pregabalin use in simulated disease treatment. This statement is based on the "open field" test results, where the motor-oriented rats’ behavior was evaluated. Administration of M+gabapentin and M+pregabalin showed positive dynamics of the motor activity: the number of squares crossed increased by 80.86% (p<0.05 and 81.73% (р<0.05 respectively. Maximum recovery of the research activity (peeking in "mink" was re­gis­tered in animals administered M+pregabalin: the increase rate was 300% (r<0.05 comparing with the 12th day of ex­periment. It was shown, that 5-days administration of M+gabapentin and M+pregabalin caused muscle tone impro­ve­ment by 190% (p<0.05 and 200% (p<0.05 respectively, comparing with animals with untreated multiple sclerosis. A sig­ni­fi­cant increase of analgesic activity of M+pregabalin and M+gabapentin combinations used together with me­thyl­pred­nisolone by 4.1 (p<0.05 and 3.6 (p<0.05 times was registered comparing with the initial methylprednisolone background.

  6. Smart business for smart users? : A social science agenda for developing smart grids

    NARCIS (Netherlands)

    Verbong, G.P.J.; Verkade, N.; Verhees, B.; Huijben, J.C.C.M.; Höffken, J.I.; Beaulieu, A.; de Wilde, J.; Scherpen, J.M.A.

    2016-01-01

    The promise of smart grids is very attractive. However, it is not yet clear what the future smart grid will look like. Although most researchers acknowledge that users will play a more prominent role in smart grids, there is a lot of uncertainty on this issue. To counter the strong techno-logical

  7. Smart grids - French Expertise

    International Nuclear Information System (INIS)

    2015-11-01

    The adaptation of electrical systems is the focus of major work worldwide. Bringing electricity to new territories, modernizing existing electricity grids, implementing energy efficiency policies and deploying renewable energies, developing new uses for electricity, introducing electric vehicles - these are the challenges facing a multitude of regions and countries. Smart Grids are the result of the convergence of electrical systems technologies with information and communications technologies. They play a key role in addressing the above challenges. Smart Grid development is a major priority for both public and private-sector actors in France. The experience of French companies has grown with the current French electricity system, a system that already shows extensive levels of 'intelligence', efficiency and competitiveness. French expertise also leverages substantial competence in terms of 'systems engineering', and can provide a tailored response to meet all sorts of needs. French products and services span all the technical and commercial building blocks that make up the Smart Grid value chain. They address the following issues: Improving the use and valuation of renewable energies and decentralized means of production, by optimizing the balance between generation and consumption. Strengthening the intelligence of the transmission and distribution grids: developing 'Supergrid', digitizing substations in transmission networks, and automating the distribution grids are the focus of a great many projects designed to reinforce the 'self-healing' capacity of the grid. Improving the valuation of decentralized flexibilities: this involves, among others, deploying smart meters, reinforcing active energy efficiency measures, and boosting consumers' contribution to grid balancing, via practices such as demand response which implies the aggregation of flexibility among residential, business, and/or industrial sites. Addressing current technological challenges, in

  8. Smart Tourism: a practice approach

    DEFF Research Database (Denmark)

    Ren, Carina Bregnholm; Petersen, Morten Krogh; Nielsen, Tanja Knoblauch

    2018-01-01

    by technology and data, but must be understood as a socio-technical and collaborative accomplishment. This entails seeing seemingly mundane issues as central to developing Smart Tourism and to link the development of Smart Tourism to transformations in the practices of everyday organizational life.......In this chapter, we explore how a Smart Destination is imagined and grappled with at an organizational level in its first and tentative stages of development. Drawing on practice theory and research in the North Denmark Region, we show how the idea of Smart Tourism is embraced by almost all...... of the stakeholders in the area, while the full potentials of this new phenomenon are experienced as difficult to realize. Abstaining from seeing Smart Tourism as a unilinear technological or digital evolution, we present four situated configurations of Smart Tourism. We argue that Smart Tourism is not made up solely...

  9. Smart Circuit Breaker Communication Infrastructure

    Directory of Open Access Journals (Sweden)

    Octavian Mihai MACHIDON

    2017-11-01

    Full Text Available The expansion of the Internet of Things has fostered the development of smart technologies in fields such as power transmission and distribution systems (as is the Smart Grid and also in regard to home automation (the Smart Home concept. This paper addresses the network communication infrastructure for a Smart Circuit Breaker system, a novel application at the edge of the two afore-mentioned systems (Smart Grid and Smart Home. Such a communication interface has high requirements from functionality, performance and security point of views, given the large amount of distributed connected elements and the real-time information transmission and system management. The paper describes the design and implementation of the data server, Web interface and the embedded networking capabilities of the smart circuit breakers, underlining the protocols and communication technologies used.

  10. Decentral Smart Grid Control

    Science.gov (United States)

    Schäfer, Benjamin; Matthiae, Moritz; Timme, Marc; Witthaut, Dirk

    2015-01-01

    Stable operation of complex flow and transportation networks requires balanced supply and demand. For the operation of electric power grids—due to their increasing fraction of renewable energy sources—a pressing challenge is to fit the fluctuations in decentralized supply to the distributed and temporally varying demands. To achieve this goal, common smart grid concepts suggest to collect consumer demand data, centrally evaluate them given current supply and send price information back to customers for them to decide about usage. Besides restrictions regarding cyber security, privacy protection and large required investments, it remains unclear how such central smart grid options guarantee overall stability. Here we propose a Decentral Smart Grid Control, where the price is directly linked to the local grid frequency at each customer. The grid frequency provides all necessary information about the current power balance such that it is sufficient to match supply and demand without the need for a centralized IT infrastructure. We analyze the performance and the dynamical stability of the power grid with such a control system. Our results suggest that the proposed Decentral Smart Grid Control is feasible independent of effective measurement delays, if frequencies are averaged over sufficiently large time intervals.

  11. Smart homes as a base for smart grids; Smart Home als Basis fuer Smart Grid

    Energy Technology Data Exchange (ETDEWEB)

    Segbusch, Klaus von [ABB AG, Mannheim (Germany). Team Business Development Smart Grids; Struwe, Christian [Busch-Jaeger Elektro GmbH, Luedenscheid (Germany)

    2010-09-15

    Integration of renewable energy sources requires more intelligent distribution systems, i.e. so-called smart grids. For this, it is necessary to integrate the end customers in grid operation, giving them financial incentives, information in near real time from the utility, and means for automatic control of their consumption. (orig.)

  12. Smart(er) Research

    DEFF Research Database (Denmark)

    Pries-Heje, Jan

    2016-01-01

    This is an answer and an elaboration to Carsten Sørensens’ “The Curse of the Smart Machine?”. My answer disagrees with the postulate of a mainframe focus within the IS field. Instead I suggest that it is a struggle between old and new science. The answer then agrees with the notion that we need n...

  13. Smart, stretchable supercapacitors.

    Science.gov (United States)

    Chen, Xuli; Lin, Huijuan; Chen, Peining; Guan, Guozhen; Deng, Jue; Peng, Huisheng

    2014-07-09

    Smart supercapacitors are developed by depositing conducting polymers onto aligned carbon-nanotube sheets. These supercapacitors rapidly and reversibly demonstrate color changes in response to a variation in the level of stored energy and the chromatic transitions can be directly observed by the naked eye. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Modelling Chinese Smart Grid

    DEFF Research Database (Denmark)

    Yuksel, Ender; Nielson, Hanne Riis; Nielson, Flemming

    In this document, we consider a specific Chinese Smart Grid implementation and try to address the verification problem for certain quantitative properties including performance and battery consumption. We employ stochastic model checking approach and present our modelling and analysis study using...

  15. Towards Smart City Learning

    DEFF Research Database (Denmark)

    Rehm, Matthias; Stan, Catalin; Wøldike, Niels Peter

    2015-01-01

    , the concept of smart city learning is exploited to situate learning about geometric shapes in concrete buildings and thus make them more accessible for younger children. In close collaboration with a local school a game for 3rd graders was developed and tested on a field trip and in class. A mixed measures...

  16. Decentral Smart Grid Control

    International Nuclear Information System (INIS)

    Schäfer, Benjamin; Matthiae, Moritz; Timme, Marc; Witthaut, Dirk

    2015-01-01

    Stable operation of complex flow and transportation networks requires balanced supply and demand. For the operation of electric power grids—due to their increasing fraction of renewable energy sources—a pressing challenge is to fit the fluctuations in decentralized supply to the distributed and temporally varying demands. To achieve this goal, common smart grid concepts suggest to collect consumer demand data, centrally evaluate them given current supply and send price information back to customers for them to decide about usage. Besides restrictions regarding cyber security, privacy protection and large required investments, it remains unclear how such central smart grid options guarantee overall stability. Here we propose a Decentral Smart Grid Control, where the price is directly linked to the local grid frequency at each customer. The grid frequency provides all necessary information about the current power balance such that it is sufficient to match supply and demand without the need for a centralized IT infrastructure. We analyze the performance and the dynamical stability of the power grid with such a control system. Our results suggest that the proposed Decentral Smart Grid Control is feasible independent of effective measurement delays, if frequencies are averaged over sufficiently large time intervals. (paper)

  17. EU Smart City Governance

    Directory of Open Access Journals (Sweden)

    Carmela Gargiulo

    2013-11-01

    Full Text Available In recent years European Commission has developed a set of documents for Members States tracing, directly or indirectly, recommendations for the transformation of the European city. The paper wants to outline which future EU draws for the city, through an integrated and contextual reading of addresses and strategies contained in the last documents, a future often suggested as Smart City. Although the three main documents (Cohesion Policy 2014-2020 of European Community, Digital Agenda for Europe and European Urban Agenda face the issue of the future development of European cities from different points of view, which are respectively cohesion social, ICT and urban dimension, each of them pays particular attention to urban and territorial dimension, identified by the name of Smart City. In other words, the paper aims at drawing the scenario of evolution of Smart Cities that can be delineated through the contextual reading of the three documents. To this end, the paper is divided into three parts: the first part briefly describes the general contents of the three European economic plan tools; the second part illustrates the scenarios for the future of the European city contained in each document; the third part seeks to trace the evolution of the Smart Cities issue developed by the set of the three instruments, in order to provide the framework of European Community for the near future of our cities. 

  18. Smart grid voor comfort

    NARCIS (Netherlands)

    Zeiler, W.; Vissers, D.R.; Maaijen, H.N.; Kling, W.L.; Velden, van der J.A.J.; Larsen, J.P.

    2012-01-01

    Er vindt onderzoek plaats naar een nieuwe regelstrategie gebaseerd op de toepassing van een draadloos sensor netwerk dat is gekoppeld aan het smart grid. Doel van deze regelstrategie is om op gebruikersniveau energie te kunnen besparen met behoud of zelfs verbetering van het individueel comfort. Er

  19. Smart Start Evaluation Plan.

    Science.gov (United States)

    Bryant, Donna; Burchinal, Margaret; Buysse, Virginia; Kotch, Jonathan; Maxwell, Kelly; Neenan, Peter; Noblit, George; Orthner, Dennis; Peisner-Feinberg, Ellen; Telfair, Joseph

    Smart Start is North Carolina's partnership between state government and local leaders, service providers, and families to better serve children under 6 years of age and their families. This report describes the comprehensive plan to evaluate the state and local goals and objectives of the program, focusing on the components addressing the…

  20. Smart Structures and Materials

    Indian Academy of Sciences (India)

    function. It is reasonable to expect that all engineering design should be smart, and not dumb. But one can still make a distinction .... among the sensors, the actuators and the decision-making centre(s). ..... basic emotions like fear or pleasure.

  1. Modelling the smart farm

    Directory of Open Access Journals (Sweden)

    Michael J. O'Grady

    2017-09-01

    Full Text Available Smart farming envisages the harnessing of Information and Communication Technologies as an enabler of more efficient, productive, and profitable farming enterprises. Such technologies do not suffice on their own; rather they must be judiciously combined to deliver meaningful information in near real-time. Decision-support tools incorporating models of disparate farming activities, either on their own or in combination with other models, offer one popular approach; exemplars include GPFARM, APSIM, GRAZPLAN amongst many others. Such models tend to be generic in nature and their adoption by individual farmers is minimal. Smart technologies offer an opportunity to remedy this situation; farm-specific models that can reflect near real-time events become tractable using such technologies. Research on the development, and application of farm-specific models is at a very early stage. This paper thus presents an overview of models within the farming enterprise; it then reviews the state-of the art in smart technologies that promise to enable a new generation of enterprise-specific models that will underpin future smart farming enterprises.

  2. Controlling smart grid adaptivity

    OpenAIRE

    Toersche, Hermen; Nykamp, Stefan; Molderink, Albert; Hurink, Johann L.; Smit, Gerardus Johannes Maria

    2012-01-01

    Methods are discussed for planning oriented smart grid control to cope with scenarios with limited predictability, supporting an increasing penetration of stochastic renewable resources. The performance of these methods is evaluated with simulations using measured wind generation and consumption data. Forecast errors are shown to affect worst case behavior in particular, the severity of which depends on the chosen adaptivity strategy and error model.

  3. The effect of ginger for relieving of primary dysmenorrhoea

    International Nuclear Information System (INIS)

    Jenabi, E.

    2013-01-01

    Objective: To assess the effectiveness of ginger in providing relief to patients of primary dysmenorrhoea. Methods: The clinical trial was conducted at Toyserkan Azad University in western Iran from July 10 to September 5, 2010. It comprised of 70 female students of the university with primary dysmenorrhoea. The subjects were randomly divided in to two equal groups and were given either placebo or ginger in capsule form for 3 days in first menstruation cycles. They graded the severity of their pain using a visual analogue scale. A 5-point Likert scale was used to assess response to treatment. Wilcoxor's rank-sum test was used to compare the severity of pain in the two groups. Results: Compared with the baseline, the decrease in the visual analogue scores of post-therapy pain in the ginger group was significantly greater than that for placebo group. In the ginger group, 29 (82.85%) subjects reported an improvement in nausea symptoms, compared with 16 (47.05%) in the placebo group. Conclusion: Ginger is effective in minimising the pain severity in primary dysmenorrhoea. (author)

  4. An integral effect test facility of the SMART, SMART ITL

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hyun Sik; Moon, Sang Ki; Kim, Yeon Sik; Cho, Seok; Choi, Ki Yong; Bae, Hwang; Kim, Dong Eok; Choi, Nam Hyun; Min, Kyoung Ho; Ko, Yung Joo; Shin, Yong Cheol; Park, Rae Joon; Lee, Won Jae; Song, Chul Hwa; Yi, Sung Jae [KAERI, Daejeon (Korea, Republic of)

    2012-10-15

    SMART (System integrated Modular Advanced ReacTor) is a 330 MWth integral pressurized water reactor (iPWR) developed by KAERI and had obtained standard design approval (SDA) from Korean regulatory authority on July 2012. In this SMART design main components including a pressurizer, reactor coolant pumps and steam generators are installed in a reactor pressure vessel without any large connecting pipes. As the LBLOCA scenario is inherently excluded, its safety systems could be simplified only to ensure the safety during the SBLOCA scenarios and the other system transients. An integral effect test loop for the SMART (SMART ITL), or called as FESTA, had been designed to simulate the integral thermal hydraulic behavior of the SMART. The objectives of the SMART ITL are to investigate and understand the integral performance of reactor systems and components and the thermal hydraulic phenomena occurred in the system during normal, abnormal and emergency conditions, and to verify the system safety during various design basis events of the SMART. The integral effect test data will also be used to validate the related thermal hydraulic models of the safety analysis code such as TASS/SMR S, which is used for performance and accident analysis of the SMART design. This paper introduces the scaling analysis and scientific design of the integral test facility of the SMART, SMART ITL and its scaling analysis results.

  5. Efficacy of biorhythmic transdermal combined hormone treatment in relieving climacteric symptoms: a pilot study

    Directory of Open Access Journals (Sweden)

    B Formby

    2011-02-01

    Full Text Available B Formby, F SchmidtThe Rasmus Institute for Medical Research, Program in Reproductive Endocrinology, Santa Barbara, CA, USAObjective: To evaluate the efficacy of a combination of bioidentical combined 17β-estradiol and progesterone transdermal delivery system (lipophilic emulsion-type base to relieve climacteric symptoms. The hormonal replacement was given during a period of 6 months at four different cyclic doses to mimic the normal ovary secretory pattern.Design: An open, randomized, comparative, between-patient trial conducted over 6 months in 29 menopausal women with climacteric symptoms assessed with the Kupperman index at baseline and during treatments. Saliva and serum values of 17β-estradiol and progesterone were quantitated before treatment and after 3 and 6 months. Pharmacokinetic data following transdermal administration of 17β-estradiol (0.3 mg, daily and progesterone (100 mg, daily were calculated from saliva levels using high-performance liquid chromatography analysis.Results: Improvement in climacteric symptoms was reported in 93% of women evaluated before and after 3 and 6 months of treatment. Values of saliva 17β-estradiol increased after 6 months from 0.6 ± 0.3 pg/mL to 14.1 ± 3.3 pg/mL, and the values of serum 17β-estradiol increased from 3.3 ± 2.8 pg/mL to 80.6 ± 21.9 pg/mL. Of responders, 88% characterized symptom relief as complete. No adverse health-related events were attributed to the bioidentical hormone therapy. Time to maximum saliva concentrations (Tmax, in all experimental cases, was observed after 6 hours. Baseline values were reached within 24 hours, indicating a diurnal rhythm of 17β-estradiol seen in normally cyclic women over the 24-hour period, ie, its daily biological rhythm.Conclusion: Percutaneous absorption of 17β-estradiol, as well as the absorption of progesterone, was associated with relief of climacteric symptoms. The cyclical transdermal delivery of combined bioidentical hormones may be

  6. Diclofenac epolamine topical patch relieves pain associated with ankle sprain

    Directory of Open Access Journals (Sweden)

    David R Lionberger

    2011-03-01

    Full Text Available David R Lionberger1, Eric Joussellin2, Arturo Lanzarotti3, Jillmarie Yanchick4, Merrell Magelli5 1Southwest Orthopedic Group, LLP, Houston, Texas, USA; 2Institut National du Sport, Paris, France; 3Institut Biochimique SA, Pambionoranco, Switzerland; 4Alpharma Pharmaceuticals LLC, a wholly owned subsidiary of King Pharmaceuticals®, Inc, Piscataway, New Jersey, USA; 5GTx, Inc, Memphis, Tennessee, USABackground: Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs, which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclofenac epolamine topical patch (DETP, 1.3%, a topical NSAID for the treatment of acute minor sprains and strains.Methods: This multicenter, randomized, placebo-controlled clinical study enrolled adult patients (n = 134 with acute ankle pain (due to a minor sprain occurring less than 48 hours prior to entering the study. Patients were treated with either the DETP or a placebo topical patch daily for seven days. Pain intensity was evaluated during the first six hours after application of the patch, and on treatment days 1, 2, 3, and 7.Results: Patients treated with the DETP experienced a significantly greater reduction in pain associated with their ankle injury compared with placebo, beginning four hours after the first patch application (P = 0.02. The DETP was well tolerated and was comparable with placebo in terms of safety.Conclusion: Overall, the results of this study demonstrate that the DETP is an effective analgesic for local treatment of pain in mild acute ankle sprain.Keywords: soft tissue injury, acute pain, visual analog scale, efficacy, tolerability 

  7. Smart photonic materials for theranostic applications

    Science.gov (United States)

    Keum, Do Hee; Beack, Songeun; Hahn, Sei Kwang

    2017-05-01

    We developed melanoidin nanoparticles for in vivo noninvasive photoacoustic mapping of sentinel lymph nodes, photoacoustic tomography of gastro-intestinal tracts, and photothermal ablation cancer therapy. In addition, we developed cell-integrated poly(ethylene glycol) hydrogels for in vivo optogenetic sensing and therapy. Real-time optical readout of encapsulated heat-shock-protein-coupled fluorescent reporter cells made it possible to measure the nanotoxicity of cadmium-based quantum dots in vivo. Using optogenetic cells producing glucagon-like peptide-1, we performed lightcontrolled diabetic therapy for glucose homeostasis. Finally, we developed a smart contact lens composed of biosensors, drug delivery systems, and power sources for the treatment of diabetes as a model disease.

  8. SmartInspect: Smart Contract Inspection Technical Report

    OpenAIRE

    Bragagnolo , Santiago; Rocha , Henrique ,; Denker , Marcus; Ducasse , Stéphane

    2017-01-01

    Smart contracts are embedded procedures stored with the data they act upon. Debugging deployed Smart Contracts is a difficult task since once deployed, the code cannot be reexecuted and inspecting a simple attribute is not easily possible because data is encoded. In this technical report, we present SmartInspect to address the lack of inspectability of a deployed contract. Our solution analyses the contract state by using decompilation techniques and a mirror-based architecture to represent t...

  9. Smart City and Smart Tourism: A Case of Dubai

    OpenAIRE

    M. Sajid Khan; Mina Woo; Kichan Nam; Prakash K. Chathoth

    2017-01-01

    Over the past decade, the advent of new technology has brought about the emergence of smart cities aiming to provide their stakeholders with technology-based solutions that are effective and efficient. Insofar as the objective of smart cities is to improve outcomes that are connected to people, systems and processes of businesses, government and other public- and private-sector entities, its main goal is to improve the quality of life of all residents. Accordingly, smart tourism has emerged o...

  10. Towards a smart learning environment for smart city governance

    OpenAIRE

    Hammad, R.; Ludlow, D.; Computer Science and Creative Technology; Centre for Sustainable Planning

    2016-01-01

    Educational services provided to various stakeholders need to be actively developed to accommodate the diversity of learning models and to get the advantages of available resources (e.g. data) in smart cities governance. Despite the substantial literature on smart cities, for Technology-Enhanced Learning (TEL) and its related domains such as learning analytics and big data, little effort has been given to the creation of connectivity to smart cities governance to meet stakeholders’ demands, e...

  11. [Theory analysis and clinical application of spirit-regulating and pain-relieving acupuncture method].

    Science.gov (United States)

    Chen, Liang; Tang, Lewei; Du, Huaibin; Zheng, Hui; Liang, Fanrong

    2015-04-01

    The theoretical foundation and scientific connotation of spirit-regulating and pain-relieving acupuncture method as well as its clinical application for pain are discussed. During spirit regulation, attention should be paid on regulating heart and brain, while acupoints should be selected mainly from the Heart Meridian, Pericardium Meridian and Governor Vessel. It has significant efficacy for refractory pain in clinical treatment. Spirit-regulating and pain-relieving acupuncture method is development of acupuncture treating spirit, and it is an important method for pain in clinic. Improvement on sensitization of pain center and brain function is considered as one of the mechanisms in spirit-regulating and pain-relieving acupuncture method.

  12. Smart blood pressure holter.

    Science.gov (United States)

    İlhan, İlhan

    2018-03-01

    In this study, a wireless blood pressure holter that can be used with smart mobile devices was developed. The developed blood pressure holter consists of two parts, which are a smart mobile device and a cuff. The smart mobile device is used as a recording, control and display device through a developed interface, while the cuff was designed to take measurements from the arm. Resistor-Capacitor (RC) and digital filters were used on the cuff that communicates with the smart mobile device via Bluetooth. The blood pressure was estimated using the Simple Hill Climbing Algorithm (HCA). It is possible to measure instantaneous or programmable blood pressure and heart rate values at certain intervals using this holter. The test was conducted with 30 individuals at different ages with the guidance of a specialist health personnel. The results showed that an accuracy at 93.89% and 91.95% rates could be obtained for systolic and diastolic pressure values, respectively, when compared with those obtained using a traditional sphygmomanometer. The accuracy level for the heart rate was measured as 97.66%. Furthermore, this device was tested day and night in the holter mode in terms of working time, the continuity of the Bluetooth connection and the reliability of the measurement results. The test results were evaluated separately in terms of measurement accuracy, working time, the continuity of the Bluetooth connection and the reliability of the measurement results. The measurement accuracy for systolic, diastolic blood pressure and heart rate values was obtained as 93.89%, 91.95% and 97.66%, respectively. The maximum number of measurements which can be conducted with four 1000 mA alkaline batteries at 20 min intervals was found approximately 79 (little more than 24 h). In addition, it was determined that the continuity of the Bluetooth connection and the reliability of the measurement results were automatically achieved through the features in the interface developed for the

  13. Smart learning services based on smart cloud computing.

    Science.gov (United States)

    Kim, Svetlana; Song, Su-Mi; Yoon, Yong-Ik

    2011-01-01

    Context-aware technologies can make e-learning services smarter and more efficient since context-aware services are based on the user's behavior. To add those technologies into existing e-learning services, a service architecture model is needed to transform the existing e-learning environment, which is situation-aware, into the environment that understands context as well. The context-awareness in e-learning may include the awareness of user profile and terminal context. In this paper, we propose a new notion of service that provides context-awareness to smart learning content in a cloud computing environment. We suggest the elastic four smarts (E4S)--smart pull, smart prospect, smart content, and smart push--concept to the cloud services so smart learning services are possible. The E4S focuses on meeting the users' needs by collecting and analyzing users' behavior, prospecting future services, building corresponding contents, and delivering the contents through cloud computing environment. Users' behavior can be collected through mobile devices such as smart phones that have built-in sensors. As results, the proposed smart e-learning model in cloud computing environment provides personalized and customized learning services to its users.

  14. Smart Learning Services Based on Smart Cloud Computing

    Directory of Open Access Journals (Sweden)

    Yong-Ik Yoon

    2011-08-01

    Full Text Available Context-aware technologies can make e-learning services smarter and more efficient since context-aware services are based on the user’s behavior. To add those technologies into existing e-learning services, a service architecture model is needed to transform the existing e-learning environment, which is situation-aware, into the environment that understands context as well. The context-awareness in e-learning may include the awareness of user profile and terminal context. In this paper, we propose a new notion of service that provides context-awareness to smart learning content in a cloud computing environment. We suggest the elastic four smarts (E4S—smart pull, smart prospect, smart content, and smart push—concept to the cloud services so smart learning services are possible. The E4S focuses on meeting the users’ needs by collecting and analyzing users’ behavior, prospecting future services, building corresponding contents, and delivering the contents through cloud computing environment. Users’ behavior can be collected through mobile devices such as smart phones that have built-in sensors. As results, the proposed smart e-learning model in cloud computing environment provides personalized and customized learning services to its users.

  15. The smart - development and technology; Der smart - Entwicklung und Technik

    Energy Technology Data Exchange (ETDEWEB)

    Goppelt, G.

    1999-06-01

    The smart is the first representative of a radically new vehicle concept, with minimum space requirements and trend-setting in terms of ecology, safety, and individualism. The new design is not rooted in any tradition. The contribution describes the development process and constructional features of the smart. [Deutsch] Der smart ist der erste Vertreter eines voellig neuen Fahrzeugkonzepts. Bei kleinstem Raumbedarf soll er neue Massstaebe bei Oekologie, Sicherheit und Individualitaet setzen. Entstanden ist eine konsequente Neukonstruktion, die sich von bisherigen Traditionen loest. In diesem Beitrag sind der Entwicklungsprozess sowie die Konstruktionsmerkmale des smart beschrieben. (orig.)

  16. Smart City and Smart Tourism: A Case of Dubai

    Directory of Open Access Journals (Sweden)

    M. Sajid Khan

    2017-12-01

    Full Text Available Over the past decade, the advent of new technology has brought about the emergence of smart cities aiming to provide their stakeholders with technology-based solutions that are effective and efficient. Insofar as the objective of smart cities is to improve outcomes that are connected to people, systems and processes of businesses, government and other public- and private-sector entities, its main goal is to improve the quality of life of all residents. Accordingly, smart tourism has emerged over the past few years as a subset of the smart city concept, aiming to provide tourists with solutions that address specific travel related needs. Dubai is an emerging tourism destination that has implemented smart city and smart tourism platforms to engage various stakeholders. The objective of this study is to identify best practices related to Dubai’s smart city and smart tourism. In so doing, Dubai’s mission and vision along with key dimensions and pillars are identified in relation to the advancements in the literature while highlighting key resources and challenges. A Smart Tourism Dynamic Responsive System (STDRS framework is proposed while suggesting how Dubai may able to enhance users’ involvement and their overall experience.

  17. Smart Grid: Network simulator for smart grid test-bed

    International Nuclear Information System (INIS)

    Lai, L C; Ong, H S; Che, Y X; Do, N Q; Ong, X J

    2013-01-01

    Smart Grid become more popular, a smaller scale of smart grid test-bed is set up at UNITEN to investigate the performance and to find out future enhancement of smart grid in Malaysia. The fundamental requirement in this project is design a network with low delay, no packet drop and with high data rate. Different type of traffic has its own characteristic and is suitable for different type of network and requirement. However no one understands the natural of traffic in smart grid. This paper presents the comparison between different types of traffic to find out the most suitable traffic for the optimal network performance.

  18. Smart grid: hope or hype?

    DEFF Research Database (Denmark)

    Lunde, Morten; Røpke, Inge; Heiskanen, Eva

    2016-01-01

    how their (intentional or unintentional) choices serve to create or maintain certain boundaries in smart grid development: for example, an exclusive focus on electricity within the broader context of a sustainable energy system. As serious investment starts being made in the smart grid, concepts like......The smart grid is an important but ambiguous element in the future transition of the European energy system. The current paper unpacks one influential national vision of the smart grid to identify what kinds of expectations guide the work of smart grid innovators and how the boundaries of the smart...... research and development and to attract new players into the field. A scenario process such as that demonstrated in this article can serve to articulate some of these implicit assumptions and help actors to navigate the ongoing transition. On the basis of our analysis, European policy makers might consider...

  19. Smart Sensor ASIC for Nuclear Power Monitoring

    International Nuclear Information System (INIS)

    Kerwin, David B.; Merkel, Kenneth G.; Rouxel, Olivier

    2013-06-01

    Mixed-signal integrated circuits are used in a variety of applications where ionizing radiation is present, including satellites, space vehicles, nuclear reactor monitoring, medical imaging, and cancer therapy. While total ionizing radiation is present in each of these environments, the type of radiation (e.g. heavy ions vs. high-energy x-rays) and other environmental factors present unique challenges to the mixed-signal designer. This paper discusses a Smart Sensor radiation hardened, mixed-signal, application specific integrated circuit (ASIC) specifically designed for sensor monitoring in a nuclear reactor environment. Results after exposure to gamma rays, neutrons, and temperatures up to 200 deg. C are reported. (authors)

  20. Smart Energi i Hjemmet

    DEFF Research Database (Denmark)

    Jensen, Ole Michael

    Med denne rapport foreligger en evaluering af det såkaldte SEIH-projekt: Smart Energi i Hjemmet. Projektet er gennemført i samarbejde med 191 husejere i Middelfart Kommune med formål at afsøge mulighederne for at opnå energibesparelser i enfamiliehuse ved at bruge automatik til at sænke temperatu......Med denne rapport foreligger en evaluering af det såkaldte SEIH-projekt: Smart Energi i Hjemmet. Projektet er gennemført i samarbejde med 191 husejere i Middelfart Kommune med formål at afsøge mulighederne for at opnå energibesparelser i enfamiliehuse ved at bruge automatik til at sænke...

  1. Smart parking barrier

    KAUST Repository

    Alharbi, Abdulrazaq M.

    2016-05-06

    Various methods and systems are provided for smart parking barriers. In one example, among others, a smart parking barrier system includes a movable parking barrier located at one end of a parking space, a barrier drive configured to control positioning of the movable parking barrier, and a parking controller configured to initiate movement of the parking barrier, via the barrier drive. The movable parking barrier can be positioned between a first position that restricts access to the parking space and a second position that allows access to the parking space. The parking controller can initiate movement of the movable parking barrier in response to a positive identification of an individual allowed to use the parking space. The parking controller can identify the individual through, e.g., a RFID tag, a mobile device (e.g., a remote control, smartphone, tablet, etc.), an access card, biometric information, or other appropriate identifier.

  2. Engineering the smart factory

    Science.gov (United States)

    Harrison, Robert; Vera, Daniel; Ahmad, Bilal

    2016-10-01

    The fourth industrial revolution promises to create what has been called the smart factory. The vision is that within such modular structured smart factories, cyber-physical systems monitor physical processes, create a virtual copy of the physical world and make decentralised decisions. This paper provides a view of this initiative from an automation systems perspective. In this context it considers how future automation systems might be effectively configured and supported through their lifecycles and how integration, application modelling, visualisation and reuse of such systems might be best achieved. The paper briefly describes limitations in current engineering methods, and new emerging approaches including the cyber physical systems (CPS) engineering tools being developed by the automation systems group (ASG) at Warwick Manufacturing Group, University of Warwick, UK.

  3. Communication technologies in smart grid

    Directory of Open Access Journals (Sweden)

    Miladinović Nikola

    2013-01-01

    Full Text Available The role of communication technologies in Smart Grid lies in integration of large number of devices into one telecommunication system. This paper provides an overview of the technologies currently in use in electric power grid, that are not necessarily in compliance with the Smart Grid concept. Considering that the Smart Grid is open to the flow of information in all directions, it is necessary to provide reliability, protection and security of information.

  4. Smart metering gateway works as Smart Home Energy Manager; Smart Metering Gateway als Smart Home Energy Manager

    Energy Technology Data Exchange (ETDEWEB)

    Walter, Klaus-Dieter [SSV Software Systems GmbH, Hannover (Germany)

    2011-07-01

    The installation of smart meters together with real time consumption data visualization doesn't help to save energy CO2 emissions. With regards to refinancing options, the situation in Germany has been quite different since the middle of last year for buildings equipped with a photovoltaic system. If a heat pump system is also present, intelligent energy use in conjunction with smart meters can save considerable amounts of money. A Smart Home Energy Manager (SHEM) automates the energy saving. (orig.)

  5. Advanced smart-photosensitizers for more effective cancer treatment.

    Science.gov (United States)

    Park, Wooram; Cho, Soojeong; Han, Jieun; Shin, Heejun; Na, Kun; Lee, Byeongdu; Kim, Dong-Hyun

    2017-12-19

    Photodynamic therapy (PDT) based upon the use of light and photosensitizers (PSs) has been used as a novel treatment approach for a variety of tumors. It, however, has several major limitations in the clinic: poor water solubility, long-term phototoxicity, low tumor targeting efficacy, and limited light penetration. With advances in nanotechnology, materials science, and clinical interventional imaging procedures, various smart-PSs have been developed for improving their cancer-therapeutic efficacy while reducing the adverse effects. Here, we briefly review state-of-the-art smart-PSs and discuss the future directions of PDT technology.

  6. Air Force Smart Bases

    Science.gov (United States)

    2017-10-19

    initiates notification to all personnel on the base, the giant voice announces a lock down, everyone’s smart device shows an alarm requesting...location of the detected sound, they easily find a hunter and send his picture back to the IOC, where the hunter’s identity is verified through facial...computer goes into sleep mode, the thermostat goes back to unoccupied mode and his door locks as he walks through. Meanwhile over in the IOC

  7. Simulating the Smart Grid

    OpenAIRE

    Pöchacker, Manfred; Sobe, Anita; Elmenreich, Wilfried

    2013-01-01

    Major challenges for the transition of power systems do not only tackle power electronics but also communication technology, power market economy and user acceptance studies. Simulation is an important research method therein, as it helps to avoid costly failures. A common smart grid simulation platform is still missing. We introduce a conceptual model of agents in multiple flow networks. Flow networks extend the depth of established power flow analysis through use of networks of information ...

  8. Smart Cities Will Need Chemistry

    Directory of Open Access Journals (Sweden)

    Alexandru WOINAROSCHY

    2016-06-01

    Full Text Available A smart city is a sustainable and efficient urban centre that provides a high quality of life to its inhabitants through optimal management of its resources. Chemical industry has a key role to play in the sustainable evolution of the smart cities. Additionally, chemistry is at the heart of all modern industries, including electronics, information technology, biotechnology and nano-technology. Chemistry can make the smart cities project more sustainable, more energy efficient and more cost effective. There are six broad critical elements of any smart city: water management systems; infrastructure; transportation; energy; waste management and raw materials consumption. In all these elements chemistry and chemical engineering are deeply involved.

  9. Wireless Communications in Smart Grid

    Science.gov (United States)

    Bojkovic, Zoran; Bakmaz, Bojan

    Communication networks play a crucial role in smart grid, as the intelligence of this complex system is built based on information exchange across the power grid. Wireless communications and networking are among the most economical ways to build the essential part of the scalable communication infrastructure for smart grid. In particular, wireless networks will be deployed widely in the smart grid for automatic meter reading, remote system and customer site monitoring, as well as equipment fault diagnosing. With an increasing interest from both the academic and industrial communities, this chapter systematically investigates recent advances in wireless communication technology for the smart grid.

  10. Smart nanomaterials for biomedics.

    Science.gov (United States)

    Choi, Soonmo; Tripathi, Anuj; Singh, Deepti

    2014-10-01

    Nanotechnology has become important in various disciplines of technology and science. It has proven to be a potential candidate for various applications ranging from biosensors to the delivery of genes and therapeutic agents to tissue engineering. Scaffolds for every application can be tailor made to have the appropriate physicochemical properties that will influence the in vivo system in the desired way. For highly sensitive and precise detection of specific signals or pathogenic markers, or for sensing the levels of particular analytes, fabricating target-specific nanomaterials can be very useful. Multi-functional nano-devices can be fabricated using different approaches to achieve multi-directional patterning in a scaffold with the ability to alter topographical cues at scale of less than or equal to 100 nm. Smart nanomaterials are made to understand the surrounding environment and act accordingly by either protecting the drug in hostile conditions or releasing the "payload" at the intended intracellular target site. All of this is achieved by exploiting polymers for their functional groups or incorporating conducting materials into a natural biopolymer to obtain a "smart material" that can be used for detection of circulating tumor cells, detection of differences in the body analytes, or repair of damaged tissue by acting as a cell culture scaffold. Nanotechnology has changed the nature of diagnosis and treatment in the biomedical field, and this review aims to bring together the most recent advances in smart nanomaterials.

  11. Integrated smart structures wingbox

    Science.gov (United States)

    Simon, Solomon H.

    1993-09-01

    One objective of smart structures development is to demonstrate the ability of a mechanical component to monitor its own structural integrity and health. Achievement of this objective requires the integration of different technologies, i.e.: (1) structures, (2) sensors, and (3) artificial intelligence. We coordinated a team of experts from these three fields. These experts used reliable knowledge towards the forefront of their technologies and combined the appropriate features into an integrated hardware/software smart structures wingbox (SSW) test article. A 1/4 in. hole was drilled into the SSW test article. Although the smart structure had never seen damage of this type, it correctly recognized and located the damage. Based on a knowledge-based simulation, quantification and assessment were also carried out. We have demonstrated that the SSW integrated hardware & software test article can perform six related functions: (1) identification of a defect; (2) location of the defect; (3) quantification of the amount of damage; (4) assessment of performance degradation; (5) continued monitoring in spite of damage; and (6) continuous recording of integrity data. We present the successful results of the integrated test article in this paper, along with plans for future development and deployment of the technology.

  12. For smart electric grids

    International Nuclear Information System (INIS)

    Tran Thiet, Jean-Paul; Leger, Sebastien; Bressand, Florian; Perez, Yannick; Bacha, Seddik; Laurent, Daniel; Perrin, Marion

    2012-01-01

    The authors identify and discuss the main challenges faced by the French electric grid: the management of electricity demand and the needed improvement of energy efficiency, the evolution of consumer's state of mind, and the integration of new production capacities. They notably outline that France have been living until recently with an electricity abundance, but now faces the highest consumption peaks in Europe, and is therefore facing higher risks of power cuts. They also notice that the French energy mix is slowly evolving, and outline the problems raised by the fact that renewable energies which are to be developed, are decentralised and intermittent. They propose an overview of present developments of smart grids, and outline their innovative characteristics, challenges raised by their development and compare international examples. They show that smart grids enable a better adapted supply and decentralisation. A set of proposals is formulated about how to finance and to organise the reconfiguration of electric grids, how to increase consumer's responsibility for peak management and demand management, how to create the conditions of emergence of a European market of smart grids, and how to support self-consumption and the building-up of an energy storage sector

  13. Smart Meter Rollout: Intelligente Messsysteme als Schnittstelle zum Kunden im Smart Grid und Smart Market

    Science.gov (United States)

    Vortanz, Karsten; Zayer, Peter

    Das Gesetz zur Digitalisierung der Energiewende ist verabschiedet. Ab 2017 sind moderne Messeinrichtungen (mME) und intelligente Messsysteme (iMSys) zu verbauen und zu betreiben. Der "deutsche Weg" für die Einführung von Smart Metern sieht einen stufenweisen Rollout sowie ein Höchstmaß an Informations- und Datensicherheit vor. Dabei spielen iMSys und mME eine wichtige Rolle bei der Neugestaltung der intelligenten Netze (Smart Grids) und des neuen Marktmodells (Smart Market). Dieser Beitrag beschäftigt sich mit den neuen Gesetzen, den Marktrollen und ihren Aufgaben, Datenschutz und Datensicherheit, dem iMSys als sichere Lösung, dem sicheren Betrieb von Smart Meter Gateways, Smart Grid - Smart Market, dem Zusammenspiel zwischen reguliertem Bereich und Markt, den Einsatzbereichen der iMSys sowie den Auswirkungen auf Prozesse und Systeme und gibt Handlungsempfehlungen.

  14. The role of smart home in smart real estate

    NARCIS (Netherlands)

    Allameh, E.; Heidari Jozam, M.; Vries, de B.; Timmermans, H.J.P.; Beetz, J.; Mozaffar, F.

    2012-01-01

    Purpose – The purpose of this paper is to review an emerging type of dwelling, indicated as Smart Home, with a focus on future user lifestyles and needs. Trends toward sustainability and technological changes dramatically alter the concepts of Smart Home. Consequently, real estate decisions are

  15. Smart Grid Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Craig [National Rural Electric Cooperative Association, Arlington, VA (United States); Carroll, Paul [National Rural Electric Cooperative Association, Arlington, VA (United States); Bell, Abigail [National Rural Electric Cooperative Association, Arlington, VA (United States)

    2015-03-11

    The National Rural Electric Cooperative Association (NRECA) organized the NRECA-U.S. Department of Energy (DOE) Smart Grid Demonstration Project (DE-OE0000222) to install and study a broad range of advanced smart grid technologies in a demonstration that spanned 23 electric cooperatives in 12 states. More than 205,444 pieces of electronic equipment and more than 100,000 minor items (bracket, labels, mounting hardware, fiber optic cable, etc.) were installed to upgrade and enhance the efficiency, reliability, and resiliency of the power networks at the participating co-ops. The objective of this project was to build a path for other electric utilities, and particularly electrical cooperatives, to adopt emerging smart grid technology when it can improve utility operations, thus advancing the co-ops’ familiarity and comfort with such technology. Specifically, the project executed multiple subprojects employing a range of emerging smart grid technologies to test their cost-effectiveness and, where the technology demonstrated value, provided case studies that will enable other electric utilities—particularly electric cooperatives— to use these technologies. NRECA structured the project according to the following three areas: Demonstration of smart grid technology; Advancement of standards to enable the interoperability of components; and Improvement of grid cyber security. We termed these three areas Technology Deployment Study, Interoperability, and Cyber Security. Although the deployment of technology and studying the demonstration projects at coops accounted for the largest portion of the project budget by far, we see our accomplishments in each of the areas as critical to advancing the smart grid. All project deliverables have been published. Technology Deployment Study: The deliverable was a set of 11 single-topic technical reports in areas related to the listed technologies. Each of these reports has already been submitted to DOE, distributed to co-ops, and

  16. Pain-relieving properties of topically applied morphine on arterial leg ulcers: a pilot study.

    NARCIS (Netherlands)

    Jansen, M.M.; Horst, J.C. van der; Valk, P.G.M. van der; Kuks, P.F.M.; Zylicz, Z.; Sorge, A.A. van

    2009-01-01

    OBJECTIVE: To assess whether topical morphine is pharmacologically effective in relieving pain from ulcers caused by arterial insufficiency and identify whether this effect is centrally or peripherally mediated. METHOD: The analgesic effect of a topically applied hydrogel containing 0.5% of morphine

  17. Using psychodrama to relieve social barriers in an autistic child: A case study and literature review

    Directory of Open Access Journals (Sweden)

    Jing Li

    2015-12-01

    Conclusions: It was possible for autistic children to relieve social barriers by implementing psychodrama training, then to improve the social cognitive ability and enhance the social function of the autistic children. These results provided basic Clinical implications for exploring a new intervention technique to reduce autistic symptom severity.

  18. Misuse of Prescription Pain Relievers: The Buzz Takes Your Breath Away. Permanently.

    Science.gov (United States)

    ... have taken prescription pain relievers, here are the danger signs to watch for: Slow breathing (less than ... لعربية | Kreyòl Ayisyen | Français | Polski | Português | Italiano | Deutsch | 日本語 | ف ...

  19. Korean Emotional Laborers' Job Stressors and Relievers: Focus on Work Conditions and Emotional Labor Properties.

    Science.gov (United States)

    Lee, Garam

    2015-12-01

    The present study aims to investigate job stressors and stress relievers for Korean emotional laborers, specifically focusing on the effects of work conditions and emotional labor properties. Emotional laborers are asked to hide or distort their real emotions in their interaction with clients. They are exposed to high levels of stress in the emotional labor process, which leads to serious mental health risks including burnout, depression, and even suicide impulse. Exploring job stressors and relieving factors would be the first step in seeking alternatives to protect emotional laborers from those mental health risks. Using the third wave data of Korean Working Conditions Survey, logistic regression analysis was conducted for two purposes: to examine the relations of emotional labor and stress, and to find out job stressors and relievers for emotional laborers. The chances of stress arousal are 3.5 times higher for emotional laborers; emotional laborers experience double risk-burden for stress arousal. In addition to general job stressors, emotional laborers need to bear burdens related to emotional labor properties. The effect of social support at the workplace is not significant for stress relief, unlike common assumptions, whereas subjective satisfaction (wage satisfaction and work-life balance) is proven to have relieving effects on emotional laborers' job stress. From the results, the importance of a balanced understanding of emotional labor for establishing effective policies for emotional laborer protection is stressed.

  20. Oxygen relieves the CO2 and acetate dependency of Lactobacillus johnsonii NCC 533

    NARCIS (Netherlands)

    Hertzberger, R.Y.; Pridmore, R.D.; Gysler, C.; Kleerebezem, M.; Teixeira de Mattos, M.J.

    2013-01-01

    Oxygen relieves the CO2 and acetate dependency of Lactobacillus johnsonii NCC 533. The probiotic Lactobacillus johnsonii NCC 533 is relatively sensitive to oxidative stress; the presence of oxygen causes a lower biomass yield due to early growth stagnation. We show however that oxygen can also be

  1. Directing traffic on DNA-How transcription factors relieve or induce transcriptional interference.

    Science.gov (United States)

    Hao, Nan; Palmer, Adam C; Dodd, Ian B; Shearwin, Keith E

    2017-03-15

    Transcriptional interference (TI) is increasingly recognized as a widespread mechanism of gene control, particularly given the pervasive nature of transcription, both sense and antisense, across all kingdoms of life. Here, we discuss how transcription factor binding kinetics strongly influence the ability of a transcription factor to relieve or induce TI.

  2. Prescription Pain Reliever Abuse and Dependence among Adolescents: A Nationally Representative Study

    Science.gov (United States)

    Wu, Li-Tzy; Ringwalt, Christopher L.; Mannelli, Paolo; Patkar, Ashwin A.

    2008-01-01

    The study investigates the prevalence, patterns, and correlates of adolescents' abuse, sub-threshold dependence, and dependence on prescription pain relievers (PPRs) in a nationally representative sample. Results show dependence on PPRs can take place without abuse and that sub-threshold dependence could have implications for major diagnostic…

  3. SMART-NPA evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hee Kyung; Lee, G. H.; Yoon, H. Y.; Kim, H. C. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2002-05-01

    SMART(System-integrated Modular Advanced ReacTor) is a 330 MWt integral reactor which is currently under development at Korea Atomic Energy Research Institute for desalination and electricity generation. SMART-NPA is the second user interface part of TASS/SMR in order to improve GUI(Graphic User Interface). Using SMART-NPA the analyzer not only can see the running status of SMART but make change of major SMART parameters. TASS/SMR, the calculation part, was written in Fortran whereas the first user interface part, called TASSWin, was written in Visual C{sup ++}. For these reason, the ActiveX control was chosen as the solution of SMART-NPA development. The five ActiveX controls were built in Visual Basic. They were Overview, Primary, Secondary, PRHRS and Control Panel ActiveX controls. They were contained in tab control, and can easily selected by user. They could communicate with TASSWin using many interface functions. The graph screens were also developed for the display of major variable's trend. The purpose of this report is the verification of SMART-NPA. The input decks were 100-200-100% power maneuvering operation, Feed Line Break Accident and user's input on Control Panel. The results of SMART-NPA for these cases were compared with the results of TASS/SMR stand alone version. The comparison results were same respectively. And all screens of SMART-NPA reflected the calculated results of TASS/SMR very well. That means SMART-NPA was calculated results of TASS/SMR very well. That means SMART-NPA was verified. 9 refs., 30 figs., 4 tabs. (Author)

  4. Managing Emergency Situations in the Smart City: The Smart Signal

    Directory of Open Access Journals (Sweden)

    Ángel Asensio

    2015-06-01

    Full Text Available In a city there are numerous items, many of them unnoticed but essential; this is the case of the signals. Signals are considered objects with reduced technological interest, but in this paper we prove that making them smart and integrating in the IoT (Internet of Things could be a relevant contribution to the Smart City. This paper presents the concept of Smart Signal, as a device conscious of its context, with communication skills, able to offer the best message to the user, and as a ubiquitous element that contributes with information to the city. We present the design considerations and a real implementation and validation of the system in one of the most challenging environments that may exist in a city: a tunnel. The main advantages of the Smart Signal are the improvement of the actual functionality of the signal providing new interaction capabilities with users and a new sensory mechanism of the Smart City.

  5. Managing Emergency Situations in the Smart City: The Smart Signal.

    Science.gov (United States)

    Asensio, Ángel; Blanco, Teresa; Blasco, Rubén; Marco, Álvaro; Casas, Roberto

    2015-06-18

    In a city there are numerous items, many of them unnoticed but essential; this is the case of the signals. Signals are considered objects with reduced technological interest, but in this paper we prove that making them smart and integrating in the IoT (Internet of Things) could be a relevant contribution to the Smart City. This paper presents the concept of Smart Signal, as a device conscious of its context, with communication skills, able to offer the best message to the user, and as a ubiquitous element that contributes with information to the city. We present the design considerations and a real implementation and validation of the system in one of the most challenging environments that may exist in a city: a tunnel. The main advantages of the Smart Signal are the improvement of the actual functionality of the signal providing new interaction capabilities with users and a new sensory mechanism of the Smart City.

  6. Is the 'blue' colour convention for inhaled reliever medications important? A UK-based survey of healthcare professionals and patients with airways disease.

    Science.gov (United States)

    Fletcher, Monica; Scullion, Jane; White, John; Thompson, Bronwen; Capstick, Toby

    2016-11-03

    In many countries, short-acting β 2 -agonist inhalers have traditionally been coloured blue. This inhaled therapy has also conventionally been known as a 'reliever' by patients and healthcare professionals (HCPs), in comparison with 'preventer' medications (inhaled steroids). With the rapidly changing market in inhaled therapy for COPD and asthma and growing numbers of devices, there has been some concern that the erosion of traditional colour conventions is leading to patients (and HCPs) becoming confused about the role of different therapies. In order to assess whether there was concern over the perceived changing colour conventions, the UK Inhaler Group carried out a large online survey of patients and HCPs. The aim was to determine how patients and HCPS identify and describe inhaled drugs, and how this might impact on use of medicines and safety. The results of the survey highlighted the importance of the term 'blue inhaler' for patients with only 11.3% never referring to the colour when referring to their inhaler. For HCPs, 95% felt colour conventions were important when referring to reliever medication. In addition, HCPs appear to refer to inhalers mainly by colour when talking to patients. Our conclusions were that the concept of a 'blue inhaler' remains important to patients and healthcare professionals. These results add to the debate about the need to formalise the colour coding of inhaled therapies, in particular using the colour blue for inhalers for rapid relief of symptoms, as this convention may be an important measure and contributor to patient safety. Our survey should provide impetus for all interested parties to discuss and agree a formal industry-wide approach to colour coding of inhaled therapies for the benefit of patients and carers and HCPs.

  7. Comparison of Prandtl–Ishlinskiı and Preisach modeling for smart devices applications

    Energy Technology Data Exchange (ETDEWEB)

    Al Janaideh, Mohammad [Department of Mechanical and Industrial Engineering, The Mechatronics and Microsystems Design Laboratory, University of Toronto, Toronto (Canada); Department of Mechatronics Engineering, The University of Jordan, Amman 11942 (Jordan); Davino, Daniele, E-mail: davino@unisannio.it [Department of Engineering, University of Sannio, I-82100 Benevento (Italy); Krejčí, Pavel [Institute of Mathematics, Czech Academy of Sciences, Zitna 25, CZ-11567 Praha 1 (Czech Republic); Visone, Ciro [Department of Engineering, University of Sannio, I-82100 Benevento (Italy)

    2016-04-01

    Hysteresis of smart devices should be modeled in order to improve the performances and to relieve the control system tasks. Prandtl–Ishlinskiı (PI) and Generalized Prandtl–Ishlinskiı (GPI) hysteresis operators are popular because of their easiness of implementation and of the availability of inverse closed formulas. Nevertheless, PI and GPI are a subset of Preisach model (PM). Therefore, in principle, they are limited in representing hysteretic behaviors with respect to PM. In this paper, a first attempt to study the representation error of GPI with respect to general Preisach hysteretic behavior is presented and evaluated through two numerical experiments.

  8. Improving Photovoltaic and Electric Vehicle Penetration in Distribution Grids with Smart Transformer

    DEFF Research Database (Denmark)

    Huang, Shaojun; Pillai, Jayakrishnan Radhakrishna; Liserre, Marco

    2013-01-01

    High penetration of electrical vehicles (EVs) and photovoltaics (PVs) can cause significant voltage issues in low voltage distribution grids. To certain extent, the transformer with on-load tap changers can regulate its output voltage, thus relieving the voltage issues and improve the hosting...... capacity of the grid. Smart transformer (ST) is a more powerful component providing faster and superior voltage regulation, as it can regulate the voltage, the frequency and the harmonic behavior of each feeder. This paper will discuss the benefit of this new feature offered by ST through simulation......, analysis and comparison with traditional transformer, where load flow analysis, optimization and multiple line drop compensation (MLDC) methods are involved....

  9. Who will buy smart glasses?

    DEFF Research Database (Denmark)

    Rauschnabel, Philipp; Brem, Alexander; Ivens, Bjørn S.

    2015-01-01

    Recent market studies reveal that augmented reality (AR) devices, such as smart glasses, will substantially influence the media landscape. Yet, little is known about the intended adoption of smart glasses, particularly: Who are the early adopters of such wearables? We contribute to the growing bo...

  10. Smart City trends and ambitions

    NARCIS (Netherlands)

    de Wijs, Lisanne; Witte, P.A.; de Klerk, Daniel; Geertman, S.C.M.

    2017-01-01

    Research into smart city projects and applications has been increasing in recent years (Meijer & Bolivar, 2015). The smart city concept is mostly considered from a technology-oriented perspective that stresses the usage of data technologies, big data and ICT to ‘smarten up’ cities. In contrast,

  11. Design considerations for smart microgrids

    NARCIS (Netherlands)

    Wattjes, F.D.; Slootweg, J.G.

    2013-01-01

    The sustainable transition towards a smarter electricity system with an emphasis on decentralized systems and additional functionalities will be facilitated in the near future by smart (micro) grids. Smart (micro) Grids are very complex systems which must be developed in an efficient, effective and

  12. Preliminary design of smart fuel

    International Nuclear Information System (INIS)

    Kim, Y.; Ha, D.; Park, S.; Nahm, K.; Lee, K.; Kim, J.

    2007-01-01

    SMART (System-integrated Modular Advanced Reactor) is a novel light water rector with a modular, integral primary system configuration. This concept has been developing a 660 MWt by Korean Nuclear Power Industry Group with KAERI. SMART is being developed for use as an energy source for small-scale power generation and seawater desalination. Although the design of SMART is based on the current pressurized water reactor technology, new technologies such as enhanced safety, and passive safety have been applied, and system simplification and modularization, innovations in manufacturing and installation technologies have been implemented culminating in a design that has enhanced safety and economy, and is environment -friendly. In this paper described the preliminary design of the nuclear Fuel for this SMART, the design concept and the characteristics of SMART Fuel. In specially this paper describe the optimization of grid span adjustment to improve the thermal performance of the SMART Fuel as well as to improve the seismic resistance performance of the SMART Fuel, it is not easy to improve the both performance simultaneously because of design parameter of each performance inversely proportional. SMART Fuel enable to extra-long extended fuel cycle length and resistance of proliferation, enhanced safety, improved economics and reduced nuclear waste

  13. Good standards for smart meters

    NARCIS (Netherlands)

    Hoenkamp, R.A.; Huitema, G.B.

    2012-01-01

    This paper examines what lessons can be learned from the rollout of smart meters in the Netherlands to improve the European smart meter standardization. This study is based on the case of the Dutch meter rollout which preparations started in 2005 but finally was delayed until 2011 by governmental

  14. What is smart for retailing?

    NARCIS (Netherlands)

    Pantano, Eleonora; Timmermans, Harry

    2014-01-01

    While the last decade has seen increasing interest in the smart city phenomenon from both scholars and practitioners, little attention has been paid to what extent retailing might be considered as part of smart cities, with benefits for all the actors involved in the process. In fact, retailing is

  15. Smart Cards and remote entrusting

    Science.gov (United States)

    Aussel, Jean-Daniel; D'Annoville, Jerome; Castillo, Laurent; Durand, Stephane; Fabre, Thierry; Lu, Karen; Ali, Asad

    Smart cards are widely used to provide security in end-to-end communication involving servers and a variety of terminals, including mobile handsets or payment terminals. Sometime, end-to-end server to smart card security is not applicable, and smart cards must communicate directly with an application executing on a terminal, like a personal computer, without communicating with a server. In this case, the smart card must somehow trust the terminal application before performing some secure operation it was designed for. This paper presents a novel method to remotely trust a terminal application from the smart card. For terminals such as personal computers, this method is based on an advanced secure device connected through the USB and consisting of a smart card bundled with flash memory. This device, or USB dongle, can be used in the context of remote untrusting to secure portable applications conveyed in the dongle flash memory. White-box cryptography is used to set the secure channel and a mechanism based on thumbprint is described to provide external authentication when session keys need to be renewed. Although not as secure as end-to-end server to smart card security, remote entrusting with smart cards is easy to deploy for mass-market applications and can provide a reasonable level of security.

  16. Smart antennas in aerospace applications

    NARCIS (Netherlands)

    Verpoorte, Jaco; Schippers, Harmen; Roeloffzen, C.G.H.; Marpaung, D.A.I.

    2010-01-01

    The interest in Smart Antennas for aerospace applications is growing. This paper describes smart antennas which can be used on aircraft. Two aerospace applications are discussed in more detail: a phased array antenna with optical beam forming and a large vibrating phased array antenna with

  17. Prototyping a Smart City

    DEFF Research Database (Denmark)

    Korsgaard, Henrik; Brynskov, Martin

    In this paper, we argue that by approaching the so-called Smart City as a design challenge, and an interaction design perspective, it is possible to both uncover existing challenges in the interplay between people, technology and society, as well as prototype possible futures. We present a case...... in which we exposed data about the online communication between the citizens and the municipality on a highly visible media facade, while at the same time prototyped a tool that enabled citizens to report ‘bugs’ within the city....

  18. SMART Product Innovation

    DEFF Research Database (Denmark)

    Cramer-Petersen, Claus L.; Ahmed-Kristensen, Saeema; Li, Xuemeng

    2016-01-01

    . The ambition of The Danish Industry Foundation and The Kata Foundation was to develop a method; a robust and specific approach to ensure that product innovation in Danish enterprises in practice would result in products of the highest quality, producible at lower costs and profitable at competitive prices...... products to our neighboring countries continues to suffer. The customers’ financial capacity has been reduced and cheaper products from Asia and other regions have found their way into our local markets. Competition is fierce – especially pricewise. This was the starting point for the SMART project...

  19. Smart power grids 2011

    CERN Document Server

    Keyhani, Ali

    2012-01-01

    Electric power systems are experiencing significant changes at the worldwide scale in order to become cleaner, smarter, and more reliable. This edited book examines a wide range of topics related to these changes, which are primarily caused by the introduction of information technologies, renewable energy penetration, digitalized equipment, new operational strategies, and so forth. The emphasis will be put on the modeling and control of smart grid systems. This book addresses research topics such as high efficiency transforrmers, wind turbines and generators, fuel cells, or high speed turbines

  20. Smart contracts sobre Bitcoin

    OpenAIRE

    Andreu Alemany, Josep Miquel

    2016-01-01

    El present treball final de màster realitza una introducció als smart contracts. El treball introdueix el concepte de contracte intel·ligent, els seus usos i alguns exemples existents. Seguidament proporciona les nocions necessàries de les transaccions del protocol Bitcoin per poder implementar un contracte intel·ligent, usant la blockchain que ofereix el protocol. Per últim, s'explica la implementació d'un contracte intel·ligent usant bitcoin: un canal de micropagaments. El presente traba...

  1. Mischief Humor in Smart and Playable Cities

    NARCIS (Netherlands)

    Nijholt, Anton; Nijholt, Anton

    2017-01-01

    In smart cities we can expect to witness human behavior that is not be different from human behavior in present-day cities. There will be demonstrations, flash mobs, and organized events to provoke the smart city establishment. Smart cities will have bugs that can be exploited by hackers. Smart

  2. Smart Inverters for Utility and Industry Applications

    DEFF Research Database (Denmark)

    Xue, Yaosuo; Guerrero, Josep M.

    2015-01-01

    Smart inverters are emerging with increasing renewable energy and smart grid development. While the recent work reviewed mostly focuses on defining standardized control functionalities and smart grid communication protocols, we take a holistic approach in this paper and propose a holon-type smart...

  3. Interactive application of a virtual smart home

    NARCIS (Netherlands)

    Allameh, E.; Heidari Jozam, M.; Vries, de B.; Timmermans, H.J.P.

    2014-01-01

    Smart Homes confront many challenges trying to move from vision to reality. Poor understanding of the concept of Smart Homes by both designers and end users causes many challenges in accepting smart homes by public. To overcome this problem, user participation in Smart Home design is advocated. On

  4. Electricity usage scheduling in smart building environments using smart devices.

    Science.gov (United States)

    Lee, Eunji; Bahn, Hyokyung

    2013-01-01

    With the recent advances in smart grid technologies as well as the increasing dissemination of smart meters, the electricity usage of every moment can be detected in modern smart building environments. Thus, the utility company adopts different price of electricity at each time slot considering the peak time. This paper presents a new electricity usage scheduling algorithm for smart buildings that adopts real-time pricing of electricity. The proposed algorithm detects the change of electricity prices by making use of a smart device and changes the power mode of each electric device dynamically. Specifically, we formulate the electricity usage scheduling problem as a real-time task scheduling problem and show that it is a complex search problem that has an exponential time complexity. An efficient heuristic based on genetic algorithms is performed on a smart device to cut down the huge searching space and find a reasonable schedule within a feasible time budget. Experimental results with various building conditions show that the proposed algorithm reduces the electricity charge of a smart building by 25.6% on average and up to 33.4%.

  5. From climate-smart agriculture to climate-smart landscapes

    Directory of Open Access Journals (Sweden)

    Scherr Sara J

    2012-08-01

    Full Text Available Abstract Background For agricultural systems to achieve climate-smart objectives, including improved food security and rural livelihoods as well as climate change adaptation and mitigation, they often need to be take a landscape approach; they must become ‘climate-smart landscapes’. Climate-smart landscapes operate on the principles of integrated landscape management, while explicitly incorporating adaptation and mitigation into their management objectives. Results An assessment of climate change dynamics related to agriculture suggests that three key features characterize a climate-smart landscape: climate-smart practices at the field and farm scale; diversity of land use across the landscape to provide resilience; and management of land use interactions at landscape scale to achieve social, economic and ecological impacts. To implement climate-smart agricultural landscapes with these features (that is, to successfully promote and sustain them over time, in the context of dynamic economic, social, ecological and climate conditions requires several institutional mechanisms: multi-stakeholder planning, supportive landscape governance and resource tenure, spatially-targeted investment in the landscape that supports climate-smart objectives, and tracking change to determine if social and climate goals are being met at different scales. Examples of climate-smart landscape initiatives in Madagascar’s Highlands, the African Sahel and Australian Wet Tropics illustrate the application of these elements in contrasting contexts. Conclusions To achieve climate-smart landscape initiatives widely and at scale will require strengthened technical capacities, institutions and political support for multi-stakeholder planning, governance, spatial targeting of investments and multi-objective impact monitoring.

  6. Conversion of SMART I. Zur Konvertierung von SMART I

    Energy Technology Data Exchange (ETDEWEB)

    Argyris, J H; Szimmat, J; William, K J [Stuttgart Univ. (TH) (Germany, F.R.). Inst. fuer Statik und Dynamik der Luft- und Raumfahrtkonstruktionen

    1977-01-01

    The report describes the conversion of the programming system SMART I on CDC, UNIVAC and IBM computers under the BMFT grant RK 21 I/SBB 31. There were four tasks for the development of a machine-independent SMART-version: a) Updating of the CDC source library (ca. 180.000 Fortran statements); b) Conversion into double precision; c) Primary installation on UNIVAC; d) Primary installation on IBM. The conversion of the SMART I program was carried out in cooperation with the consulting firms RIB, Stuttgart, and IKOSS Stuttgart, under the leadership of ISD.

  7. Smart nanoparticles as targeting platforms for HIV infections

    Science.gov (United States)

    Adhikary, Rishi Rajat; More, Prachi; Banerjee, Rinti

    2015-04-01

    While Human Immunodeficiency Virus (HIV) infections are reducing in incidence with the advent of Highly Active Anti-retroviral Therapy (HAART), there remain a number of challenges including the existence of reservoirs, drug resistance and anatomical barriers to antiretroviral therapy. To overcome these, smart nanoparticles with stimuli responsive release are proposed for delivery of anti-retroviral agents. The paper highlights the strategic similarities between the design of smart antiretroviral nanocarriers and those optimized for cancer chemotherapy. This includes the development of nanoparticles capable of passive and active targeting as well as those that are responsive to various internal and external triggers. For antiretroviral therapy, the relevant triggers for stimuli responsive release of drugs include semen, enzymes, endosomal escape, temperature and magnetic field. Deriving from the experience of cancer chemotherapy, additional potential triggers are light and ultrasound which remain hitherto unexplored in HIV therapy. In addition, the roles of nanomicrobicides (nanogels) and virus mimetic nanoparticles are discussed from the point of view of prevention of HIV transmission. The challenges associated with translation of smart nanoparticles for HIV infections to realize the Millennium Development Goal of combating HIV infections are discussed.

  8. Smart Grid Enabled EVSE

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-01-12

    The combined team of GE Global Research, Federal Express, National Renewable Energy Laboratory, and Consolidated Edison has successfully achieved the established goals contained within the Department of Energy’s Smart Grid Capable Electric Vehicle Supply Equipment funding opportunity. The final program product, shown charging two vehicles in Figure 1, reduces by nearly 50% the total installed system cost of the electric vehicle supply equipment (EVSE) as well as enabling a host of new Smart Grid enabled features. These include bi-directional communications, load control, utility message exchange and transaction management information. Using the new charging system, Utilities or energy service providers will now be able to monitor transportation related electrical loads on their distribution networks, send load control commands or preferences to individual systems, and then see measured responses. Installation owners will be able to authorize usage of the stations, monitor operations, and optimally control their electricity consumption. These features and cost reductions have been developed through a total system design solution.

  9. A smart rock

    Science.gov (United States)

    Pressel, Phil

    2014-12-01

    This project was to design and build a protective weapon for a group of associations that believed in aliens and UFO's. They collected enough contributions from societies and individuals to be able to sponsor and totally fund the design, fabrication and testing of this equipment. The location of this facility is classified. It also eventually was redesigned by the Quartus Engineering Company for use at a major amusement park as a "shoot at targets facility." The challenge of this project was to design a "smart rock," namely an infrared bullet (the size of a gallon can of paint) that could be shot from the ground to intercept a UFO or any incoming suspicious item heading towards the earth. Some of the challenges to design this weapon were to feed cryogenic helium at 5 degrees Kelvin from an inair environment through a unique rotary coupling and air-vacuum seal while spinning the bullet at 1500 rpm and maintain its dynamic stability (wobble) about its spin axis to less than 10 micro-radians (2 arc seconds) while it operated in a vacuum. Precision optics monitored the dynamic motion of the "smart rock."

  10. Smart energy management system

    Science.gov (United States)

    Desai, Aniruddha; Singh, Jugdutt

    2010-04-01

    Peak and average energy usage in domestic and industrial environments is growing rapidly and absence of detailed energy consumption metrics is making systematic reduction of energy usage very difficult. Smart energy management system aims at providing a cost-effective solution for managing soaring energy consumption and its impact on green house gas emissions and climate change. The solution is based on seamless integration of existing wired and wireless communication technologies combined with smart context-aware software which offers a complete solution for automation of energy measurement and device control. The persuasive software presents users with easy-to-assimilate visual cues identifying problem areas and time periods and encourages a behavioural change to conserve energy. The system allows analysis of real-time/statistical consumption data with the ability to drill down into detailed analysis of power consumption, CO2 emissions and cost. The system generates intelligent projections and suggests potential methods (e.g. reducing standby, tuning heating/cooling temperature, etc.) of reducing energy consumption. The user interface is accessible using web enabled devices such as PDAs, PCs, etc. or using SMS, email, and instant messaging. Successful real-world trial of the system has demonstrated the potential to save 20 to 30% energy consumption on an average. Low cost of deployment and the ability to easily manage consumption from various web enabled devices offers gives this system a high penetration and impact capability offering a sustainable solution to act on climate change today.

  11. Smart city analytics

    DEFF Research Database (Denmark)

    Hansen, Casper; Hansen, Christian; Alstrup, Stephen

    2017-01-01

    We present an ensemble learning method that predicts large increases in the hours of home care received by citizens. The method is supervised, and uses different ensembles of either linear (logistic regression) or non-linear (random forests) classifiers. Experiments with data available from 2013 ...... is very useful when full records are not accessible or available. Smart city analytics does not necessarily require full city records. To our knowledge this preliminary study is the first to predict large increases in home care for smart city analytics.......We present an ensemble learning method that predicts large increases in the hours of home care received by citizens. The method is supervised, and uses different ensembles of either linear (logistic regression) or non-linear (random forests) classifiers. Experiments with data available from 2013...... to 2017 for every citizen in Copenhagen receiving home care (27,775 citizens) show that prediction can achieve state of the art performance as reported in similar health related domains (AUC=0.715). We further find that competitive results can be obtained by using limited information for training, which...

  12. RANCANG BANGUN APLIKASI SMART CARD INTERFACE

    OpenAIRE

    I Putu Agus Swastika; Siti Saibah Pua Luka; Yanno Dwi Ananda

    2012-01-01

    Opportunity to development smart card -based application is quite large as the need for smart card technology in various fields of both business and government agencies and BUMN. One brand that is widely used smart card is a smart card type from a vendor production NFC ACR122U ACS (Advanced Card System Limited) because prices are relatively affordable, but fairly tough. At the Thesis is done, the ACS (Advanced Card System Limited) as a manufacturer of smart card vendor type ...

  13. The Internet of things and Smart Grid

    Science.gov (United States)

    Li, Biao; Lv, Sen; Pan, Qing

    2018-02-01

    The Internet of things and smart grid are the frontier of information and Industry. The combination of Internet of things and smart grid will greatly enhance the ability of smart grid information and communication support. The key technologies of the Internet of things will be applied to the smart grid, and the grid operation and management information perception service centre will be built to support the commanding heights of the world’s smart grid.

  14. Ecosystem Based Business Model of Smart Grid

    OpenAIRE

    Lundgaard, Morten Raahauge; Ma, Zheng; Jørgensen, Bo Nørregaard

    2015-01-01

    This paper tries to investigate the ecosystem based business model in a smart grid infrastructure and the potential of value capture in the highly complex macro infrastructure such as smart grid. This paper proposes an alternative perspective to study the smart grid business ecosystem to support the infrastructural challenges, such as the interoperability of business components for smart grid. So far little research has explored the business ecosystem in the smart grid concept. The study on t...

  15. Green Technology for Smart Cities

    Science.gov (United States)

    Casini, M.

    2017-08-01

    In view of the enormous social and environmental changes at the global level, more and more cities worldwide have directed their development strategies towards smart policies aimed at sustainable mobility, energy upgrading of the building stock, increase of energy production from renewable sources, improvement of waste management and implementation of ICT infrastructures. The goal is to turn into Smart Cities, able to improve the quality of life of their inhabitants by offering a lasting opportunity for cultural, economic and social growth within a healthy, safe, stimulating and dynamic environment. After an overview of the role of cities in climate changes and environmental pollution worldwide, the article provides an up to date definition of Smart City and of its main expected features, focussing on technology innovation, smart governance and main financing and support programs. An analysis of the most interesting initiatives at the international level pursued by cities investigating the three main areas of Green Buildings, Smart grid-Smart lighting, and Smart mobility is given, with the objective to offer a broad reference for the identification of development sustainable plans and programs at the urban level within the current legislative framework.

  16. Smart market. From smart grid to the intelligent energy market; Smart Market. Vom Smart Grid zum intelligenten Energiemarkt

    Energy Technology Data Exchange (ETDEWEB)

    Aichele, Christian [Hochschule Kaiserslautern, Zweibruecken (Germany). Fachbereich Betriebswirtschaft; Doleski, Oliver D. (ed.)

    2014-07-01

    Dare more market. - The design of this postulate provides an important contribution to the success of the German energy transition. The Bundesnetzagentur has shown with its highly regarded benchmark paper on smart grids and markets leads the way towards more market in the energy sector. The therein required differentiation in a network and market sphere contributes to greater transparency on the consumer side and enables a gid releaving shift in energy consumption. The book focuses on actors and roles in the modified market circumstances as well as components and products of a future Smart Markets. Finally, to the reader concrete business models are offered. Authors from science and practice give in this book answers on how the interaction of Smart Grid and Smart Market works. [German] Mehr Markt wagen. - Die Ausgestaltung dieses Postulats liefert einen wichtigen Beitrag zum Gelingen der deutschen Energiewende. Die Bundesnetzagentur hat mit ihrem vielbeachteten Eckpunktepapier zu intelligenten Netzen und Maerkten diesen Weg in Richtung mehr Markt in der Energiewirtschaft gewiesen. Die darin geforderte Differenzierung in eine Netz- und Marktsphaere traegt zu mehr Transparenz auf der Verbraucherseite bei und ermoeglicht eine netzentlastende Verlagerung des Energieverbrauchs. Das Buch beleuchtet Akteure und Rollen im geaenderten Marktumfeld ebenso wie Komponenten und Produkte eines zukuenftigen Smart Markets. Schliesslich werden dem Leser konkrete Geschaeftsmodelle angeboten. Autoren aus Wissenschaft und Praxis geben in diesem Buch Antworten darauf, wie das Zusammenspiel von Smart Grid und Smart Market funktioniert.

  17. Acute effects of massage or active exercise in relieving muscle soreness

    DEFF Research Database (Denmark)

    Andersen, Lars L; Jay, Kenneth; Andersen, Christoffer H

    2013-01-01

    Massage is commonly believed to be the best modality for relieving muscle soreness. However, actively warming up the muscles with exercise may be an effective alternative. The purpose of this study was to compare the acute effect of massage with active exercise for relieving muscle soreness. Twenty...... healthy female volunteers (mean age 32 years) participated in this examiner-blind randomized controlled trial (ClinicalTrials.gov NCT01478451). The participants performed eccentric contractions for the upper trapezius muscle on a Biodex dynamometer. Delayed onset muscle soreness (DOMS) presented 48 hours...... later, at which the participants (a) received 10 minutes of massage of the trapezius muscle or (b) performed 10 minutes of active exercise (shoulder shrugs 10 × 10 reps) with increasing elastic resistance (Thera-Band). First, 1 treatment was randomly applied to 1 shoulder while the contralateral...

  18. The Research on the Impact of Green Beans Sports Drinks on Relieving Fatigue in Sports Training.

    Science.gov (United States)

    Qi, Li; Ying, Liu

    2015-01-01

    For researching the function of relieving fatigue of green beans sports drinks, this paper selected 60 mice as subjects. They were randomly divided into four groups (low dose group, middle dose group, high dose group and physiological saline group). Each time they were respectively feed 10g 20g/L, 40g/L, 80 g/L green beans sports drinks and 15ml/(kg.d) physiological saline. The experiment lasted for a month. We recorded weight of mice, swimming time and blood urea nitrogen indicators. The results show that green beans sports drinks can significantly prolong swimming time of mice (p beans sports drinks have a certain function of relieving physical fatigue.

  19. Automatic stress-relieving music recommendation system based on photoplethysmography-derived heart rate variability analysis.

    Science.gov (United States)

    Shin, Il-Hyung; Cha, Jaepyeong; Cheon, Gyeong Woo; Lee, Choonghee; Lee, Seung Yup; Yoon, Hyung-Jin; Kim, Hee Chan

    2014-01-01

    This paper presents an automatic stress-relieving music recommendation system (ASMRS) for individual music listeners. The ASMRS uses a portable, wireless photoplethysmography module with a finger-type sensor, and a program that translates heartbeat signals from the sensor to the stress index. The sympathovagal balance index (SVI) was calculated from heart rate variability to assess the user's stress levels while listening to music. Twenty-two healthy volunteers participated in the experiment. The results have shown that the participants' SVI values are highly correlated with their prespecified music preferences. The sensitivity and specificity of the favorable music classification also improved as the number of music repetitions increased to 20 times. Based on the SVI values, the system automatically recommends favorable music lists to relieve stress for individuals.

  20. A Novel Scheme to Relieve Parking Pressure at Tourist Attractions on Holidays

    Directory of Open Access Journals (Sweden)

    Juan Li

    2016-02-01

    Full Text Available Parking is a key component of urban transportation managements and has become a severe problem at many tourist attractions during holidays in China. This paper presents a novel scheme to relieve the holiday parking pressure. Based on the perspectives of the activity-based travel characteristics, we propose an effort to develop parking alternatives by utilizing existing traffic facilities. A conceptual model is employed to explore the influence of additional leisure activity of parking and various options of transportation modes. The results indicate that compared to commuters, the scenery is the major factor affecting tourists’ parking preference, besides parking time and cost. Based on the finding, a tourist-centered strategy is designed to satisfy the peak hours parking demands in order to relieve the parking pressure at tourist attractions during holidays.

  1. Feasibility of local stress relieving close to main shell of a large vessel

    International Nuclear Information System (INIS)

    Hancinsky, O.A.

    1978-01-01

    This work determines the feasibility of local stress relieving for a circumferential pipe-to-nozzle field weld positioned close to the main shell of a large pressure vessel. This is applicable to nuclear as well as conventional vessels. ANSYS computer program is utilized to perform thermal and thermal stress analysis and ASME Pressure Vessels Code is adhered to. Conclusions and recommendations are made with a view on their applicability in practice

  2. Euglena gracilis Z and its carbohydrate storage substance relieve arthritis symptoms by modulating Th17 immunity.

    Directory of Open Access Journals (Sweden)

    Kengo Suzuki

    Full Text Available Euglena gracilis Z is a microorganism classified as a microalga and is used as a food or nutritional supplement. Paramylon, the carbohydrate storage substance of E. gracilis Z, is reported to affect the immunological system. This study evaluated the symptom-relieving effects of E. gracilis Z and paramylon in rheumatoid arthritis in a collagen-induced arthritis mouse model. The efficacy of both substances was assessed based on clinical arthritis signs, as well as cytokine (interleukin [IL]-17, IL-6, and interferon [IFN]-γ levels in lymphoid tissues. Additionally, the knee joints were harvested and histopathologically examined. The results showed that both substances reduced the transitional changes in the visual assessment score of arthritis symptoms compared with those in the control group, indicating their symptom-relieving effects on rheumatoid arthritis. Furthermore, E. gracilis Z and paramylon significantly reduced the secretion of the cytokines, IL-17, IL-6, and IFN-γ. The histopathological examination of the control group revealed edema, inflammation, cell hyperplasia, granulation tissue formation, fibrosis, and exudate in the synovial membrane, as well as pannus formation and articular cartilage destruction in the femoral trochlear groove. These changes were suppressed in both treatment groups. Particularly, the E. gracilis Z group showed no edema, inflammation, and fibrosis of the synovial membrane, or pannus formation and destruction of articular cartilage in the femoral trochlear groove. Furthermore, E. gracilis Z and paramylon exhibited symptom-relieving effects on rheumatoid arthritis and suppressed the secretion of cytokines IL-17, IL-6, and IFN-γ. These effects were likely mediated by the regulatory activities of E. gracilis Z and paramylon on Th17 immunity. In addition, the symptom-relieving effects of both substances were comparable, which suggests that paramylon is the active component of Euglena gracilis Z.

  3. Korean Emotional Laborers' Job Stressors and Relievers: Focus on Work Conditions and Emotional Labor Properties

    OpenAIRE

    Garam Lee

    2015-01-01

    Background: The present study aims to investigate job stressors and stress relievers for Korean emotional laborers, specifically focusing on the effects of work conditions and emotional labor properties. Emotional laborers are asked to hide or distort their real emotions in their interaction with clients. They are exposed to high levels of stress in the emotional labor process, which leads to serious mental health risks including burnout, depression, and even suicide impulse. Exploring job st...

  4. Effects of herbal medicine Sijunzi decoction on rabbits after relieving intestinal obstruction

    Directory of Open Access Journals (Sweden)

    L. Li

    2017-09-01

    Full Text Available Intestinal obstruction leads to blockage of the movement of intestinal contents. After relieving the obstruction, patients might still suffer with compromised immune function and nutritional deficiency. This study aimed to evaluate the effects of Sijunzi decoction on restoring the immune function and nutritional status after relieving the obstruction. Experimental rabbits (2.5±0.2 kg were randomly divided into normal control group, 2-day intestinal obstruction group, 2-day natural recovery group, 4-day natural recovery group, 2-day treated group, and 4-day treated group. Sijunzi decoction was given twice a day to the treated groups. The concentration of markers was analyzed to evaluate the immune function and nutritional status. The concentration of interleukin-2, immunoglobulins and complement components of the treated groups were significantly higher than the natural recovery group (P<0.05. The levels of CD4+ and CD4+/CD8+ increased then decreased in the treated groups. The levels of tumor necrosis factor-α and CD8+ were significantly lower than the natural recovery group. The level of total protein in the treated groups also increased then decreased after relieving the obstruction. The levels of albumin, prealbumin and insulin-like growth factor-1 were significantly higher in the treated groups than in the natural recovery group (P<0.05. Transferrin level in the treated groups was significantly higher than the obstruction group (P<0.05. Sijunzi decoction can lessen the inflammatory response and improve the nutrition absorption after relieving the obstruction.

  5. Development of smart solar tanks

    DEFF Research Database (Denmark)

    Furbo, Simon; Andersen, Elsa

    1999-01-01

    The aim of the project is to develop smart solar tanks. A smart solar tank is a tank in which the domestic water can bee heated both by solar collectors and by an auxiliary energy supply system. The auxiliary energy supply system heats up the hot-water tank from the top and the water volume heated...... by the auxiliary energy supply system is fitted to the hot water consumption and consumption pattern. In periods with a large hot-water demand the volume is large, in periods with a small hot-water demand the volume is small. Based on measurements and calculations the advantage of smart SDHW systems is visualised....

  6. Smart market. From smart grid to the intelligent energy market

    International Nuclear Information System (INIS)

    Aichele, Christian; Doleski, Oliver D.

    2014-01-01

    Dare more market. - The design of this postulate provides an important contribution to the success of the German energy transition. The Bundesnetzagentur has shown with its highly regarded benchmark paper on smart grids and markets leads the way towards more market in the energy sector. The therein required differentiation in a network and market sphere contributes to greater transparency on the consumer side and enables a gid releaving shift in energy consumption. The book focuses on actors and roles in the modified market circumstances as well as components and products of a future Smart Markets. Finally, to the reader concrete business models are offered. Authors from science and practice give in this book answers on how the interaction of Smart Grid and Smart Market works. [de

  7. Smart earphone: Controlling tasks by earphone in smart phone by ...

    African Journals Online (AJOL)

    DR OKE

    International Journal of Engineering, Science and Technology. Vol. ... Using this technique Authors have implemented that a smart earphone system can be used to make ..... aware home: A living laboratory for ubiquitous computing research, ...

  8. Gerontechnology for demented patients: smart homes for smart aging.

    Science.gov (United States)

    Frisardi, Vincenza; Imbimbo, Bruno P

    2011-01-01

    In an aging world, maintaining good health and independence for as long as possible is essential. Instead of hospitalization or institutionalization, the elderly with chronic conditions, especially those with cognitive impairment, can be assisted in their own environment with numerous 'smart' devices that support them in their activity of daily living. A "smart home" is a residence equipped with technology that facilitates monitoring of residents to improve quality of life and promote physical independence, as well as to reduce caregiver burden. Several projects worldwide have been conducted, but some ethical and legal issues are still unresolved and, at present, there is no evidence of the effects of smart homes on health outcomes. Randomized controlled trials are needed to understand the plus and minuses of these projects, but this will only be possible with a widespread proliferation and penetration of smart homes in the social network.

  9. Survey report on smart-tribo-mechanics; Smart tribo mechanics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    Survey results of smart-tribo-mechanics are described. For the smart-tribo-mechanics differing from the conventional tribology, an intelligent system is constructed by making full use of various science and technology ranging from basic to application, to solve problems. Self-diagnosis and self-remediation, active control, passive control, and smart-biotribo-mechanics are typical methods. Electronics, telecommunication, healthcare, and new biotechnology are new and advanced application areas. In these areas, tribology to control and act to the material surface in the atomic and molecular scale should be the key technology. In addition, the smart-tribo-mechanics is expected to be used for sustaining basic industry, such as material, transportation, and life industries. 101 refs., 67 figs., 14 tabs.

  10. Effects of Competing Narratives on Public Perceptions of Opioid Pain Reliever Addiction during Pregnancy.

    Science.gov (United States)

    Kennedy-Hendricks, Alene; McGinty, Emma E; Barry, Colleen L

    2016-10-01

    Opioid pain reliever addiction has increased among women of reproductive age over the last fifteen years. News media and public attention have focused on the implications of this trend for infants exposed to opioids prenatally, with state policy responses varying in the extent to which they are punitive or public health oriented. We fielded a six-group randomized experiment among a nationally representative sample of US adults to test the effects of narratives portraying a woman with opioid pain reliever addiction during pregnancy on beliefs about people addicted to opioid pain relievers, perceptions of treatment effectiveness, policy attitudes, and emotional responses. Portraying a high socioeconomic status (SES) woman in the narrative lowered perceptions of individual blame for addiction and reduced public support for punitive policies. Depicting the barriers to treatment faced by a low SES woman lowered support for punitive policies and increased support for expanded insurance coverage for treatment. The extent to which narratives portraying successfully treated addiction affected public attitudes depended on the SES of the woman portrayed. These findings can inform the development of communication strategies to reduce stigma toward this population, reduce support for punitive policies, and increase support for more public health-oriented approaches to addressing this problem. Copyright © 2016 by Duke University Press.

  11. The relieving effects of shelter modes on physiological stress of traffic police in summer

    Science.gov (United States)

    Zheng, G. Z.; Wang, Y. J.; Bu, W. T.; Lu, Y. Z.; Li, Ke; Li, Z. H.

    2018-03-01

    In summer, high temperature and strong sun radiation last for a long time. However, traffic police still stick to their positions to ensure normal traffic order. Therefore, the health and safety of traffic police are challenged by the high temperature weather. To protect the safety of the traffic police in the outdoor high temperature environment, some shelter modes, such as sun hat and sun umbrella are selected for duty traffic police. The relieving effects on the physiological stress of the shelter modes are analyzed by comparison of the physiological parameters in these shelter modes. The results show that sun umbrella has a good effect on relieving physiological stress. And sun hat has no effect on relieving physiological stress, although it avoids the direct sunlight on the face. However, it causes the increase of the thermal sensation. This study can provide important methods for health protecting of traffic police in the outdoor high temperature environment. It also provides a theoretical support for the revision of the outdoor high temperature labour protection standard.

  12. Long Island Smart Energy Corridor

    Energy Technology Data Exchange (ETDEWEB)

    Mui, Ming [Long Island Power Authority, Uniondale, NY (United States)

    2015-02-04

    The Long Island Power Authority (LIPA) has teamed with Stony Brook University (Stony Brook or SBU) and Farmingdale State College (Farmingdale or FSC), two branches of the State University of New York (SUNY), to create a “Smart Energy Corridor.” The project, located along the Route 110 business corridor on Long Island, New York, demonstrated the integration of a suite of Smart Grid technologies from substations to end-use loads. The Smart Energy Corridor Project included the following key features: -TECHNOLOGY: Demonstrated a full range of smart energy technologies, including substations and distribution feeder automation, fiber and radio communications backbone, advanced metering infrastructure (AM”), meter data management (MDM) system (which LIPA implemented outside of this project), field tools automation, customer-level energy management including automated energy management systems, and integration with distributed generation and plug-in hybrid electric vehicles. -MARKETING: A rigorous market test that identified customer response to an alternative time-of-use pricing plan and varying levels of information and analytical support. -CYBER SECURITY: Tested cyber security vulnerabilities in Smart Grid hardware, network, and application layers. Developed recommendations for policies, procedures, and technical controls to prevent or foil cyber-attacks and to harden the Smart Grid infrastructure. -RELIABILITY: Leveraged new Smart Grid-enabled data to increase system efficiency and reliability. Developed enhanced load forecasting, phase balancing, and voltage control techniques designed to work hand-in-hand with the Smart Grid technologies. -OUTREACH: Implemented public outreach and educational initiatives that were linked directly to the demonstration of Smart Grid technologies, tools, techniques, and system configurations. This included creation of full-scale operating models demonstrating application of Smart Grid technologies in business and residential

  13. Smart material screening machines using smart materials and controls

    Science.gov (United States)

    Allaei, Daryoush; Corradi, Gary; Waigand, Al

    2002-07-01

    The objective of this product is to address the specific need for improvements in the efficiency and effectiveness in physical separation technologies in the screening areas. Currently, the mining industry uses approximately 33 billion kW-hr per year, costing 1.65 billion dollars at 0.05 cents per kW-hr, of electrical energy for physical separations. Even though screening and size separations are not the single most energy intensive process in the mining industry, they are often the major bottleneck in the whole process. Improvements to this area offer tremendous potential in both energy savings and production improvements. Additionally, the vibrating screens used in the mining processing plants are the most costly areas from maintenance and worker health and safety point of views. The goal of this product is to reduce energy use in the screening and total processing areas. This goal is accomplished by developing an innovative screening machine based on smart materials and smart actuators, namely smart screen that uses advanced sensory system to continuously monitor the screening process and make appropriate adjustments to improve production. The theory behind the development of Smart Screen technology is based on two key technologies, namely smart actuators and smart Energy Flow ControlT (EFCT) strategies, developed initially for military applications. Smart Screen technology controls the flow of vibration energy and confines it to the screen rather than shaking much of the mass that makes up the conventional vibratory screening machine. Consequently, Smart Screens eliminates and downsizes many of the structural components associated with conventional vibratory screening machines. As a result, the surface area of the screen increases for a given envelope. This increase in usable screening surface area extends the life of the screens, reduces required maintenance by reducing the frequency of screen change-outs and improves throughput or productivity.

  14. Smart and Intelligent Sensors

    Science.gov (United States)

    Lansaw, John; Schmalzel, John; Figueroa, Jorge

    2009-01-01

    John C. Stennis Space Center (SSC) provides rocket engine propulsion testing for NASA's space programs. Since the development of the Space Shuttle, every Space Shuttle Main Engine (SSME) has undergone acceptance testing at SSC before going to Kennedy Space Center (KSC) for integration into the Space Shuttle. The SSME is a large cryogenic rocket engine that uses Liquid Hydrogen (LH2) as the fuel. As NASA moves to the new ARES V launch system, the main engines on the new vehicle, as well as the upper stage engine, are currently base lined to be cryogenic rocket engines that will also use LH2. The main rocket engines for the ARES V will be larger than the SSME, while the upper stage engine will be approximately half that size. As a result, significant quantities of hydrogen will be required during the development, testing, and operation of these rocket engines.Better approaches are needed to simplify sensor integration and help reduce life-cycle costs. 1.Smarter sensors. Sensor integration should be a matter of "plug-and-play" making sensors easier to add to a system. Sensors that implement new standards can help address this problem; for example, IEEE STD 1451.4 defines transducer electronic data sheet (TEDS) templates for commonly used sensors such as bridge elements and thermocouples. When a 1451.4 compliant smart sensor is connected to a system that can read the TEDS memory, all information needed to configure the data acquisition system can be uploaded. This reduces the amount of labor required and helps minimize configuration errors. 2.Intelligent sensors. Data received from a sensor be scaled, linearized; and converted to engineering units. Methods to reduce sensor processing overhead at the application node are needed. Smart sensors using low-cost microprocessors with integral data acquisition and communication support offer the means to add these capabilities. Once a processor is embedded, other features can be added; for example, intelligent sensors can make

  15. Educating the smart city: Schooling smart citizens through computational urbanism

    Directory of Open Access Journals (Sweden)

    Ben Williamson

    2015-11-01

    Full Text Available Coupled with the ‘smart city’, the idea of the ‘smart school’ is emerging in imaginings of the future of education. Various commercial, governmental and civil society organizations now envisage education as a highly coded, software-mediated and data-driven social institution. Such spaces are to be governed through computational processes written in computer code and tracked through big data. In an original analysis of developments from commercial, governmental and civil society sectors, the article examines two interrelated dimensions of an emerging smart schools imaginary: (1 the constant flows of digital data that smart schools depend on and the mobilization of analytics that enable student data to be used to anticipate and shape their behaviours; and (2 the ways that young people are educated to become ‘computational operatives’ who must ‘learn to code’ in order to become ‘smart citizens’ in the governance of the smart city. These developments constitute an emerging educational space fabricated from intersecting standards, technologies, discourses and social actors, all infused with the aspirations of technical experts to govern the city at a distance through both monitoring young people as ‘data objects’ and schooling them as active ‘computational citizens’ with the responsibility to compute the future of the city.

  16. Hydro One smart meter/smart grid : realizing the vision

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, R. [Hydro One Networks Inc., Toronto, ON (Canada)

    2010-07-01

    Ontario's Hydro One Networks has been installing smart meters as part of its smart grid plan since 2007. The smart grid plan forms part of the utility's overall aim to create an energy conservation culture across the province. The utility now has over 1 million installed meters over a 640,000{sup 2} km territory. The smart grid planning team has adopted the use of an upgraded open protocol standards-based communications as part of its 2-way high bandwidth network. The utility is using a 1.8 Ghz worldwide interoperability for microwave access (WiMAX) spectrum designed specifically for the protection of electric utility infrastructure. The utility is now incorporating proof-of-concept applications including automated reclosers, remote terminal units, demand management devices and mobile technologies for use in its smart grid procedures. Various smart zone business scenarios were also described in this power point presentation, as well as details of Hydro One's integration plans for vendors and other power systems. tabs., figs.

  17. Smart practice: smart card design considerations in health care.

    Science.gov (United States)

    Lindley, R A; Pacheco, F

    1995-01-01

    Recent innovations in microelectronics and advances in cryptography are driving the appearance of a new generation of smart cards with wider applications; this has important repercussions for our society in the coming years. Essentially, these breakthroughs include built-in microprocessors capable of generating cryptographic transactions (e.g.,Jelectronic blinded signatures, digital pseudonyms, and digital credentials), developments toward a single electronic card offering multi-access to services such as transport, telecommunications, health, financial, and entertainment (Universal Access Services), and incorporation of personal identification technologies such as voice, eye, or skin pattern recognition. For example, by using electronic representatives or cryptographic blinded signatures, a smart card can be used for multi transactions across different organizations and under different generated pseudonyms. These pseudonyms are capable of recognizing an individual unambiguously, while none of her records can be linked [1]. Moreover, tamper-proof electronic observers would make smart cards a very attractive technology for high-security based applications, such as those in the health care field. New trends in smart card technology offer excellent privacy and confidentiality safeguards. Therefore, smart cards constitute a promising technology for the health sector in Australia and other countries around the world in their pursuit of technology to support the delivery of quality care services. This paper addresses the main issues and the key design criteria which may be of strategic importance to the success of future smart card technology in the health care sector.

  18. Smart electromechanical systems

    CERN Document Server

    2016-01-01

    This carefully edited book introduces the latest achievements of the scientists of the Russian Academy of Sciences in the field of theory and practice of Smart Electromechanical Systems (SEMS). The book also focuses on methods of designing and modeling of SEMS based on the principles of adaptability, intelligence, biomorphism of parallel kinematics and parallelism in information processing and control computation. The book chapters are dedicated to the following points of interest: - methods of design of SEMS modules and intelligent robots based on them; - synthesis of neural systems of automatic control over SEMS modules; - mathematical and computer modeling of SEMS modules and Cyber Physical Systems based on them; - vitality control and reliability analysis based on logic-and-probabilistic and logic-and-linguistic forecasting; - methods of optimization of SEMS control systems based on mathematical programming methods in ordinal scale and generalized mathematical programming; - information-measuring software...

  19. Smart network. The information nework in the smart grid; Smart Network. Das Informationsnetz im Smart Grid

    Energy Technology Data Exchange (ETDEWEB)

    Horrmeyer, Bernd [Phoenix Contact GmbH und Co. KG, Blomberg (Germany). Industrielle Netzwerkverkabelung; Wissig, Claus [Phoenix Contact GmbH und Co. KG, Blomberg (Germany). Geraeteverbindungstechnik

    2012-07-01

    So far, the distribution of electricity was constructed unidirectional - from the generating power plant over the power distribution systems to the consumer. In the last decade, the utilization of renewable energies became popular. Thus the energy flows bi-directionally in the lines. Since the current has to be consumed at the moment of generation, the control becomes more difficult when bi-directional feeding. The techniques are demanding, and the number of devices for controlling and monitoring the of the distribution networks increases. The need for digital communication between the devices increases - the existing information networks in the energy sector are not dimensioned for this. With its bi-directional supply of energy, the smart grid requires a more frequent and faster communication between the devices. New cabling concepts according to IEC 61850 provide reliable and easy to maintain electrical and optical ethernet connections.

  20. Smart Energy Europe

    DEFF Research Database (Denmark)

    Connolly, D.; Lund, H.; Mathiesen, B. V.

    2016-01-01

    is presented in terms of energy (primary energy supply), environment (carbon dioxide emissions), and economy (total annual socio-economic cost). The steps are ordered in terms of their scientific and political certainty as follows: Decommissioning nuclear power, implementing a large amount of heat savings......This study presents one scenario for a 100% renewable energy system in Europe by the year 2050. The transition from a business-as-usual situation in 2050, to a 100% renewable energy Europe is analysed in a series of steps. Each step reflects one major technological change. For each step, the impact......, converting the private car fleet to electricity, providing heat in rural areas with heat pumps, providing heat in urban areas with district heating, converting fuel in heavy-duty vehicles to a renewable electrofuel, and replacing natural gas with methane. The results indicate that by using the Smart Energy...

  1. The Market for Smart Growth

    Science.gov (United States)

    Based on several studies of market demand, the authors determined that consumer demand for smart growth would translate into more than 600,000 houses out of the approximately 2 million new housing units built in 2007.

  2. Imaging standards for smart cards

    Science.gov (United States)

    Ellson, Richard N.; Ray, Lawrence A.

    1996-02-01

    "Smart cards" are plastic cards the size of credit cards which contain integrated circuits for the storage of digital information. The applications of these cards for image storage has been growing as card data capacities have moved from tens of bytes to thousands of bytes. This has prompted the recommendation of standards by the X3B10 committee of ANSI for inclusion in ISO standards for card image storage of a variety of image data types including digitized signatures and color portrait images. This paper will review imaging requirements of the smart card industry, challenges of image storage for small memory devices, card image communications, and the present status of standards. The paper will conclude with recommendations for the evolution of smart card image standards towards image formats customized to the image content and more optimized for smart card memory constraints.

  3. Smart roadside initiative : user manual.

    Science.gov (United States)

    2015-09-01

    This document provides the user instructions for the Smart Roadside Initiative (SRI) applications including mobile and web-based SRI applications. These applications include smartphone-enabled information exchange and notification, and software compo...

  4. Smart roadside initiative : final report.

    Science.gov (United States)

    2015-09-01

    This is the Final Report for the Smart Roadside Initiative (SRI) prototype system deployment project. The SRI prototype was implemented at weigh stations in Grass Lake, Michigan and West Friendship, Maryland. The prototype was developed to integrate ...

  5. SMART SKINS - A Development Roadmap

    Science.gov (United States)

    Lochocki, Joseph M.

    1990-02-01

    The Air Force Project Forecast II identified a number of key technology initiatives for development. This paper addresses one such initiative, PT-16, Smart Skins. The concept of the Smart Skin is introduced by briefly highlighting its attributes and potential advantages over standard avionics packaging and maintenance, and then goes on to describe some of the key ingredients necessary for its development. Problem areas are brought out along with some of the required trades that must be made. Finally, a time phased development roadmap is introduced which shows Calspan's proposed sequence of technology development programs that can, in combination, lead to first functional Smart Skins implementations in narrowband form in the late 1990's and in wideband form in first decade of the twenty - first century. A Smart Skins implementation in integral aircraft skin structure form will take at least until 2010.

  6. Hadoop Oriented Smart Cities Architecture

    Science.gov (United States)

    Bologa, Ana-Ramona; Bologa, Razvan

    2018-01-01

    A smart city implies a consistent use of technology for the benefit of the community. As the city develops over time, components and subsystems such as smart grids, smart water management, smart traffic and transportation systems, smart waste management systems, smart security systems, or e-governance are added. These components ingest and generate a multitude of structured, semi-structured or unstructured data that may be processed using a variety of algorithms in batches, micro batches or in real-time. The ICT architecture must be able to handle the increased storage and processing needs. When vertical scaling is no longer a viable solution, Hadoop can offer efficient linear horizontal scaling, solving storage, processing, and data analyses problems in many ways. This enables architects and developers to choose a stack according to their needs and skill-levels. In this paper, we propose a Hadoop-based architectural stack that can provide the ICT backbone for efficiently managing a smart city. On the one hand, Hadoop, together with Spark and the plethora of NoSQL databases and accompanying Apache projects, is a mature ecosystem. This is one of the reasons why it is an attractive option for a Smart City architecture. On the other hand, it is also very dynamic; things can change very quickly, and many new frameworks, products and options continue to emerge as others decline. To construct an optimized, modern architecture, we discuss and compare various products and engines based on a process that takes into consideration how the products perform and scale, as well as the reusability of the code, innovations, features, and support and interest in online communities. PMID:29649172

  7. Nuclear design characteristics of SMART

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chung Chan; Park, Sang Yoon; Lee, Ki Bog; Zee, Sung Quun; Chang, Moon Hee [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1998-12-31

    Nuclear design bases for System-Integrated Modular Advanced ReacTor(SMART) core are presented. Based on the proposed design bases, a SMART core loading pattern is constructed and its nuclear characteristics are studied. The proposed core loading pattern satisfies 3-year cycle length and soluble boron-free operation requirements at any time during the cycle. 10 refs., 2 figs., 1 tab. (Author)

  8. Wireless smart shipboard sensor network

    OpenAIRE

    Nozik, Andrew B.

    2005-01-01

    This thesis studies the feasibility of developing a smart shipboard sensor network. The objective of the thesis is to prove that sensors can be made smart by keeping calibration constants and other relevant data such as network information stored on the sensor and a server computer. Study will focus on the design and implementation of an Ipsil IP(micro)8930 microcontroller, which is then connected, by the standard TCP/IP implementation, to a network where the sensor information can be see...

  9. Smart BIT/TSMD Integration

    Science.gov (United States)

    1991-12-01

    integracion . Smart BIT/TSMD provides Rome Laboratory with a laboratory testbed to evaluate and assess the individual characteristics as well as the integration...that assessment. These windows are color-keyed to tie together multiple windows for the same Smart BIT techniques. The display of the neural net- work... Multiple accelerometer icons of any type may therefore be placed (non-overlapping) in the accelerometer Time Line region. The BIT Time Line Editor allows

  10. Hadoop Oriented Smart Cities Architecture

    Directory of Open Access Journals (Sweden)

    Vlad Diaconita

    2018-04-01

    Full Text Available A smart city implies a consistent use of technology for the benefit of the community. As the city develops over time, components and subsystems such as smart grids, smart water management, smart traffic and transportation systems, smart waste management systems, smart security systems, or e-governance are added. These components ingest and generate a multitude of structured, semi-structured or unstructured data that may be processed using a variety of algorithms in batches, micro batches or in real-time. The ICT architecture must be able to handle the increased storage and processing needs. When vertical scaling is no longer a viable solution, Hadoop can offer efficient linear horizontal scaling, solving storage, processing, and data analyses problems in many ways. This enables architects and developers to choose a stack according to their needs and skill-levels. In this paper, we propose a Hadoop-based architectural stack that can provide the ICT backbone for efficiently managing a smart city. On the one hand, Hadoop, together with Spark and the plethora of NoSQL databases and accompanying Apache projects, is a mature ecosystem. This is one of the reasons why it is an attractive option for a Smart City architecture. On the other hand, it is also very dynamic; things can change very quickly, and many new frameworks, products and options continue to emerge as others decline. To construct an optimized, modern architecture, we discuss and compare various products and engines based on a process that takes into consideration how the products perform and scale, as well as the reusability of the code, innovations, features, and support and interest in online communities.

  11. Nuclear design characteristics of SMART

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chung Chan; Park, Sang Yoon; Lee, Ki Bog; Zee, Sung Quun; Chang, Moon Hee [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1999-12-31

    Nuclear design bases for System-Integrated Modular Advanced ReacTor(SMART) core are presented. Based on the proposed design bases, a SMART core loading pattern is constructed and its nuclear characteristics are studied. The proposed core loading pattern satisfies 3-year cycle length and soluble boron-free operation requirements at any time during the cycle. 10 refs., 2 figs., 1 tab. (Author)

  12. Smart grid applications and developments

    CERN Document Server

    Mah, Daphne; Li, Victor OK; Balme, Richard

    2014-01-01

    Meeting today's energy and climate challenges require not only technological advancement but also a good understanding of stakeholders' perceptions, political sensitivity, well-informed policy analyses and innovative interdisciplinary solutions. This book will fill this gap. This is an interdisciplinary informative book to provide a holistic and integrated understanding of the technology-stakeholder-policy interactions of smart grid technologies. The unique features of the book include the following: (a) interdisciplinary approach - by bringing in the policy dimensions to smart grid technologi

  13. The energy aware smart home

    OpenAIRE

    Jahn, M.; Jentsch, M.; Prause, C.R.; Pramudianto, F.; Al-Akkad, A.; Reiners, R.

    2010-01-01

    In this paper, we present a novel smart home system integrating energy efficiency features. The smart home application is built on top of Hydra, a middleware framework that facilitates the intelligent communication of heterogeneous embedded devices through an overlay P2P network. We interconnect common devices available in private households and integrate wireless power metering plugs to gain access to energy consumption data. These data are used for monitoring and analyzing consumed energy o...

  14. Streamlining Smart Meter Data Analytics

    OpenAIRE

    Liu, Xiufeng; Nielsen, Per Sieverts

    2015-01-01

    Today smart meters are increasingly used in worldwide. Smart meters are the advanced meters capable of measuring customer energy consumption at a fine-grained time interval, e.g., every 15 minutes. The data are very sizable, and might be from different sources, along with the other social-economic metrics such as the geographic information of meters, the information about users and their property, geographic location and others, which make the data management very complex. On the other hand, ...

  15. Hadoop Oriented Smart Cities Architecture.

    Science.gov (United States)

    Diaconita, Vlad; Bologa, Ana-Ramona; Bologa, Razvan

    2018-04-12

    A smart city implies a consistent use of technology for the benefit of the community. As the city develops over time, components and subsystems such as smart grids, smart water management, smart traffic and transportation systems, smart waste management systems, smart security systems, or e-governance are added. These components ingest and generate a multitude of structured, semi-structured or unstructured data that may be processed using a variety of algorithms in batches, micro batches or in real-time. The ICT architecture must be able to handle the increased storage and processing needs. When vertical scaling is no longer a viable solution, Hadoop can offer efficient linear horizontal scaling, solving storage, processing, and data analyses problems in many ways. This enables architects and developers to choose a stack according to their needs and skill-levels. In this paper, we propose a Hadoop-based architectural stack that can provide the ICT backbone for efficiently managing a smart city. On the one hand, Hadoop, together with Spark and the plethora of NoSQL databases and accompanying Apache projects, is a mature ecosystem. This is one of the reasons why it is an attractive option for a Smart City architecture. On the other hand, it is also very dynamic; things can change very quickly, and many new frameworks, products and options continue to emerge as others decline. To construct an optimized, modern architecture, we discuss and compare various products and engines based on a process that takes into consideration how the products perform and scale, as well as the reusability of the code, innovations, features, and support and interest in online communities.

  16. Smart Markets for Water Resources

    Science.gov (United States)

    Raffensperger, John

    2017-04-01

    Commercial water users often want to trade water, but their trades can hurt other users and the environment. So government has to check every transaction. This checking process is slow and expensive. That's why "free market" water trading doesn't work, especially with trading between a single buyer and a single seller. This talk will describe a water trading mechanism designed to solve these problems. The trading mechanism is called a "smart market". A smart market allows simultaneous many-to-many trades. It can reduce the transaction costs of water trading, while improving environmental outcomes. The smart market depends on a combination of recent technologies: hydrology simulation, computer power, and the Internet. Our smart market design uses standard hydrological models, user bids from a web page, and computer optimization to maximize the economic value of water while meeting all environmental constraints. Before the smart market can be implemented, however, users and the water agency must meet six critical prerequisites. These prerequisites may be viewed as simply good water management that should be done anyway. I will describe these prerequisites, and I will briefly discuss common arguments against water markets. This talk will be an abstract of a forthcoming book, "Smart Markets for Water Resources: A Manual for Implementation," by John F. Raffensperger and Mark W. Milke, from Springer Publishing.

  17. Research Advance in Smart Metamaterials

    Directory of Open Access Journals (Sweden)

    YU Xiang-long

    2016-07-01

    Full Text Available Metamaterials, man-made materials, enable us to design our own "atoms", and thereby to create materials with unprecedented effective properties that have not yet been found in nature. Smart metamaterial is one of those that is an intelligent perceptive to the changes from external environments and simultaneously having the capability to respond to thermal and mechanical stimuli. This paper can provide a review on these smart metamaterials in perspective of science, engineering and industrial products. We divide smart metamaterials according to what they are tuning into: optical, mechanical, thermal and coupled smart metamaterials. The rest of two techniques we addressed are modelling/simulation and fabrication/gene engineering. All of these types smart materials presented here are associated with at least five fundamental research: coupled mechanism of multi-physics fields, man-made design for atom/molecular, metamaterials coupled with natural materials, tunability of metamaterials, and mechanism of sensing metamaterials. Therefore, we give a systematic overview of various potential smart metamaterials together with the upcoming challenges in the intriguing and promising research field.

  18. Smart Nacre-inspired Nanocomposites.

    Science.gov (United States)

    Peng, Jingsong; Cheng, Qunfeng

    2018-03-15

    Nacre-inspired nanocomposites with excellent mechanical properties have achieved remarkable attention in the past decades. The high performance of nacre-inspired nanocomposites is a good basis for the further application of smart devices. Recently, some smart nanocomposites inspired by nacre have demonstrated good mechanical properties as well as effective and stable stimuli-responsive functions. In this Concept, we summarize the recent development of smart nacre-inspired nanocomposites, including 1D fibers, 2D films and 3D bulk nanocomposites, in response to temperature, moisture, light, strain, and so on. We show that diverse smart nanocomposites could be designed by combining various conventional fabrication methods of nacre-inspired nanocomposites with responsive building blocks and interface interactions. The nacre-inspired strategy is versatile for different kinds of smart nanocomposites in extensive applications, such as strain sensors, displays, artificial muscles, robotics, and so on, and may act as an effective roadmap for designing smart nanocomposites in the future. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Smart Grid Communications System Blueprint

    Science.gov (United States)

    Clark, Adrian; Pavlovski, Chris

    2010-10-01

    Telecommunications operators are well versed in deploying 2G and 3G wireless networks. These networks presently support the mobile business user and/or retail consumer wishing to place conventional voice calls and data connections. The electrical power industry has recently commenced transformation of its distribution networks by deploying smart monitoring and control devices throughout their networks. This evolution of the network into a `smart grid' has also motivated the need to deploy wireless technologies that bridge the communication gap between the smart devices and information technology systems. The requirements of these networks differ from traditional wireless networks that communications operators have deployed, which have thus far forced energy companies to consider deploying their own wireless networks. We present our experience in deploying wireless networks to support the smart grid and highlight the key properties of these networks. These characteristics include application awareness, support for large numbers of simultaneous cell connections, high service coverage and prioritized routing of data. We also outline our target blueprint architecture that may be useful to the industry in building wireless and fixed networks to support the smart grid. By observing our experiences, telecommunications operators and equipment manufacturers will be able to augment their current networks and products in a way that accommodates the needs of the emerging industry of smart grids and intelligent electrical networks.

  20. Enhancing integrated indoor/outdoor mobility in a smart campus

    OpenAIRE

    Torres Sospedra, Joaquín; Avariento, Joan; Rambla Risueño, David; Montoliu Colás, Raúl; Casteleyn, Sven; Benedito Bordonau, Mauri; Gould Carlson, Michael; Huerta Guijarro, Joaquín

    2015-01-01

    A Smart City relies on six key factors: Smart Governance, Smart People, Smart Economy, Smart Environment, Smart Living and Smart Mobility. This paper focuses on Smart Mobility by improving one of its key components: positioning. We developed and deployed a novel indoor positioning system (IPS) that is combined with an outdoor positioning system to support seamless indoor and outdoor navigation and wayfinding. The positioning system is implemented as a service in our broader cartography-based ...

  1. Smart grids are advancing, light and supple

    International Nuclear Information System (INIS)

    Petitot, Pauline

    2016-01-01

    While indicating some innovations produced by the Greenlys laboratory (SmartScan to localize losses by means of smart counters, a system for grid self-healing, Sequoia to manage a low voltage network, a tool for the prediction of photovoltaic production in real time), and also the main smart grid projects in France (Nice Grid, Solenn, SoGrid, Smart Electric Lyon, Poste intelligent, Greenlys, Smart Grids Vendee, BienVEnu), this article comments the emergence of several experiments on smart grids in France, the first drawn conclusions and recommendations. Some issues for this new architecture are discussed: the active demand management, cut-offs and flexibility, and the search for profitability

  2. Smart Home, Smart Grid, Smart Meter - digitale Konzepte und das Recht an Daten

    Science.gov (United States)

    Spiecker genannt Döhmann, Indra

    Modernes Energiemanagement setzt auf ein intelligent gesteuertes Energieinformationsnetz, das Smart Grid. In diesem ist der Smart Meter, die intelligente Messstelle beim Nutzer, ein zentrales Instrument für den wechselseitigen Austausch von Informationen. Allerdings werfen die über diverse Gesetze forcierten Informationsströme erhebliche datenschutzrechtliche Fragen auf. Der Beitrag stellt zentrale datenschutzrechtliche Leitlinien und Probleme vor und behandelt auch offene Fragestellungen.

  3. Increasing the use of 'smart' pump drug libraries by nurses: a continuous quality improvement project.

    Science.gov (United States)

    Harding, Andrew D

    2012-01-01

    The use of infusion pumps that incorporate "smart" technology (smart pumps) can reduce the risks associated with receiving IV therapies. Smart pump technology incorporates safeguards such as a list of high-alert medications, soft and hard dosage limits, and a drug library that can be tailored to specific patient care areas. Its use can help to improve patient safety and to avoid potentially catastrophic harm associated with medication errors. But when one independent community hospital in Massachusetts switched from older mechanical pumps to smart pumps, it neglected to assign an "owner" to oversee the implementation process. One result was that nurses were using the smart pump library for only 37% of all infusions.To increase pump library usage percentage-thereby reducing the risks associated with infusion and improving patient safety-the hospital undertook a continuous quality improvement project over a four-month period in 2009. With the involvement of direct care nurses, and using quantitative data available from the smart pump software, the nursing quality and pharmacy quality teams identified ways to improve pump and pump library use. A secondary goal was to calculate the hospital's return on investment for the purchase of the smart pumps. Several interventions were developed and, on the first of each month, implemented. By the end of the project, pump library usage had nearly doubled; and the hospital had completely recouped its initial investment.

  4. Verification of dimensional stability on ITER blanket shield block after stress relieving

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sa-Woong, E-mail: swkim12@nfri.re.kr; Jung, Hun-Chea; Ha, Min-Su; Shim, Hee-Jin

    2016-11-01

    Highlights: • The SB#08 FSP were manufactured by using conventional manufacturing processes such as cutting, milling, drilling and welding. • Especially, a strong back system was adopted in order to prevent welding deformation during cover plate welding process. • Post-Welding Heat Treatment (PWHT) for stress relieving and Hot He Leak Test (HHLT) were waived from the lake of huge test facility in the pre-qualification program. • The PWHT combined with the HHLT, however, were implemented to remove the residual stress and to confirm the soundness of welded parts as an internal R&D activities after the pre-qualification program. • Three dimensional inspection also carried out after the PWHT to check the dimensional stabilization. - Abstract: The tight tolerance requirement is one of key issue to manufacture the ITER blanket shield blocks (SBs) which have many interfaces with the First Wall (FW) and Vacuum Vessel (VV). Manufactured SB shall be satisfied with general tolerances (Class “C” of ISO 2768-1 and “L” of ISO 2768-2) and specific tolerance in 2D general assembly drawings. In order to fulfill the tight tolerance requirements in the final stage of SB, stress relieving after welding operations in the manufacturing process shall be performed. Hot helium leak test, Post Welding Heat Treatment (PWHT) and three-dimensional inspection before and after heat treatment were implemented by using the Full Scale Prototype (FSP) of SB in the framework of domestic R&D activities. The hot He leak test was performed at 250 °C for 30 min, and the result was satisfied the requirements. PWHT was carried out at 400 °C for 24 h by brazing furnace with test chamber. The deformation value before and after was measured by contact type coordinate measuring machine. The objective of this study is to verify dimensional stability of SB after stress relieving. The results will support to determine the machining allowance prior to welding process.

  5. Precipitating and Relieving Factors of Migraine Headache in 200 Iraqi Kurdish Patients

    Directory of Open Access Journals (Sweden)

    Ehsan K. Al-Shimmery

    2010-07-01

    Full Text Available Objectives: To study the precipitating and relieving factors of migraine headache in a group of Iraqi Kurdish patients including the effect of fasting in Ramadan, and to estimate the percentage of family history of migraine. Methods: A series of 200 migraine cases from different parts of the Kurdistan region in the North of Iraq attending the out-patient Neurology clinic at Rizgary Teaching Hospital and a private Neurology clinic at Erbil City was carried out between October 2007 and May 2008 were reviewed. The precipitating factors and relieving factors for migraine headache were registered and tabulated to be compared with others. Case definition of migraine was based on the International Headache Society (IHS criteria.Results: 33% of the patients were aged between 30-39 years, while 40.5% of patients experienced their first attack aged between 20-29 years. Stress or psychological upset was the commonest triggering factor (80%, followed by increasing physical activity (68%, change in weather (65.5%, and in relation to fasting (65%. Fasting in Ramadan was a triggering factor for headaches in 65% of patients. However, there was no significant association between the triggering factors with regards to sex difference. Relief of migraine in the studied sample was achieved using NSAIDs in 50% of patients, and sleep (45.5%. Hence, 61% of the study population had positive family history of migraine, 32.5% of them reported maternal history of migraine. Conclusion: Psychological upset, stress and excessive physical activity were the commonest triggering factors of migraine headache, while NSAID was the commonest relieving factor of migraine in this population. Family history was present in 61% of migraine patients based mainly from maternal root.

  6. Smart portable rehabilitation devices

    Directory of Open Access Journals (Sweden)

    Leahey Matt

    2005-07-01

    Full Text Available Abstract Background The majority of current portable orthotic devices and rehabilitative braces provide stability, apply precise pressure, or help maintain alignment of the joints with out the capability for real time monitoring of the patient's motions and forces and without the ability for real time adjustments of the applied forces and motions. Improved technology has allowed for advancements where these devices can be designed to apply a form of tension to resist motion of the joint. These devices induce quicker recovery and are more effective at restoring proper biomechanics and improving muscle function. However, their shortcoming is in their inability to be adjusted in real-time, which is the most ideal form of a device for rehabilitation. This introduces a second class of devices beyond passive orthotics. It is comprised of "active" or powered devices, and although more complicated in design, they are definitely the most versatile. An active or powered orthotic, usually employs some type of actuator(s. Methods In this paper we present several new advancements in the area of smart rehabilitation devices that have been developed by the Northeastern University Robotics and Mechatronics Laboratory. They are all compact, wearable and portable devices and boast re-programmable, real time computer controlled functions as the central theme behind their operation. The sensory information and computer control of the three described devices make for highly efficient and versatile systems that represent a whole new breed in wearable rehabilitation devices. Their applications range from active-assistive rehabilitation to resistance exercise and even have applications in gait training. The three devices described are: a transportable continuous passive motion elbow device, a wearable electro-rheological fluid based knee resistance device, and a wearable electrical stimulation and biofeedback knee device. Results Laboratory tests of the devices

  7. Smart portable rehabilitation devices.

    Science.gov (United States)

    Mavroidis, Constantinos; Nikitczuk, Jason; Weinberg, Brian; Danaher, Gil; Jensen, Katherine; Pelletier, Philip; Prugnarola, Jennifer; Stuart, Ryan; Arango, Roberto; Leahey, Matt; Pavone, Robert; Provo, Andrew; Yasevac, Dan

    2005-07-12

    The majority of current portable orthotic devices and rehabilitative braces provide stability, apply precise pressure, or help maintain alignment of the joints with out the capability for real time monitoring of the patient's motions and forces and without the ability for real time adjustments of the applied forces and motions. Improved technology has allowed for advancements where these devices can be designed to apply a form of tension to resist motion of the joint. These devices induce quicker recovery and are more effective at restoring proper biomechanics and improving muscle function. However, their shortcoming is in their inability to be adjusted in real-time, which is the most ideal form of a device for rehabilitation. This introduces a second class of devices beyond passive orthotics. It is comprised of "active" or powered devices, and although more complicated in design, they are definitely the most versatile. An active or powered orthotic, usually employs some type of actuator(s). In this paper we present several new advancements in the area of smart rehabilitation devices that have been developed by the Northeastern University Robotics and Mechatronics Laboratory. They are all compact, wearable and portable devices and boast re-programmable, real time computer controlled functions as the central theme behind their operation. The sensory information and computer control of the three described devices make for highly efficient and versatile systems that represent a whole new breed in wearable rehabilitation devices. Their applications range from active-assistive rehabilitation to resistance exercise and even have applications in gait training. The three devices described are: a transportable continuous passive motion elbow device, a wearable electro-rheological fluid based knee resistance device, and a wearable electrical stimulation and biofeedback knee device. Laboratory tests of the devices demonstrated that they were able to meet their design

  8. Smart sensing surveillance system

    Science.gov (United States)

    Hsu, Charles; Chu, Kai-Dee; O'Looney, James; Blake, Michael; Rutar, Colleen

    2010-04-01

    An effective public safety sensor system for heavily-populated applications requires sophisticated and geographically-distributed infrastructures, centralized supervision, and deployment of large-scale security and surveillance networks. Artificial intelligence in sensor systems is a critical design to raise awareness levels, improve the performance of the system and adapt to a changing scenario and environment. In this paper, a highly-distributed, fault-tolerant, and energy-efficient Smart Sensing Surveillance System (S4) is presented to efficiently provide a 24/7 and all weather security operation in crowded environments or restricted areas. Technically, the S4 consists of a number of distributed sensor nodes integrated with specific passive sensors to rapidly collect, process, and disseminate heterogeneous sensor data from near omni-directions. These distributed sensor nodes can cooperatively work to send immediate security information when new objects appear. When the new objects are detected, the S4 will smartly select the available node with a Pan- Tilt- Zoom- (PTZ) Electro-Optics EO/IR camera to track the objects and capture associated imagery. The S4 provides applicable advanced on-board digital image processing capabilities to detect and track the specific objects. The imaging detection operations include unattended object detection, human feature and behavior detection, and configurable alert triggers, etc. Other imaging processes can be updated to meet specific requirements and operations. In the S4, all the sensor nodes are connected with a robust, reconfigurable, LPI/LPD (Low Probability of Intercept/ Low Probability of Detect) wireless mesh network using Ultra-wide band (UWB) RF technology. This UWB RF technology can provide an ad-hoc, secure mesh network and capability to relay network information, communicate and pass situational awareness and messages. The Service Oriented Architecture of S4 enables remote applications to interact with the S4

  9. National Smart Water Grid

    Energy Technology Data Exchange (ETDEWEB)

    Beaulieu, R A

    2009-07-13

    The United States repeatedly experiences floods along the Midwest's large rivers and droughts in the arid Western States that cause traumatic environmental conditions with huge economic impact. With an integrated approach and solution these problems can be alleviated. Tapping into the Mississippi River and its tributaries, the world's third largest fresh water river system, during flood events will mitigate the damage of flooding and provide a new source of fresh water to the Western States. The trend of increased flooding on the Midwest's large rivers is supported by a growing body of scientific literature. The Colorado River Basin and the western states are experiencing a protracted multi-year drought. Fresh water can be pumped via pipelines from areas of overabundance/flood to areas of drought or high demand. Calculations document 10 to 60 million acre-feet (maf) of fresh water per flood event can be captured from the Midwest's Rivers and pumped via pipelines to the Colorado River and introduced upstream of Lake Powell, Utah, to destinations near Denver, Colorado, and used in areas along the pipelines. Water users of the Colorado River include the cities in southern Nevada, southern California, northern Arizona, Colorado, Utah, Indian Tribes, and Mexico. The proposed start and end points, and routes of the pipelines are documented, including information on right-of-ways necessary for state and federal permits. A National Smart Water Grid{trademark} (NSWG) Project will create thousands of new jobs for construction, operation, and maintenance and save billions in drought and flood damage reparations tax dollars. The socio-economic benefits of NWSG include decreased flooding in the Midwest; increased agriculture, and recreation and tourism; improved national security, transportation, and fishery and wildlife habitats; mitigated regional climate change and global warming such as increased carbon capture; decreased salinity in Colorado River water

  10. Smart Metering. Technological, economic and legal aspects. 2. ed.; Smart Metering. Technologische, wirtschaftliche und juristische Aspekte des Smart Metering

    Energy Technology Data Exchange (ETDEWEB)

    Koehler-Schute, Christiana (ed.)

    2010-07-01

    Smart metering comprises more than just meter technology, and the use of information and communication technologies is indispensable. Processes, roles and business models must be reconsidered as further challenges arise in the context of smart metering. For one, there is the operator of the metering points. Secondly, there is the end user who is in the role of an active market partner. Further, there is smart metering as a basic technology, e.g. for smart grids and smart homes. In spite of the need for action, many utilities are reluctant to introduce smart metering. Reasons for this are the cost, a lack of defined standards, and an unclear legal situation. On the other hand, smart metering offers potential for grids and distribution that should be made use of. The authors discuss all aspects of the subject. The point out the chances and limitations of smart metering and present their own experience. [German] Smart Metering geht weit ueber die Zaehlertechnologie hinaus und der Einsatz von Informations- und Kommunikationstechnologien ist unabdingbar. Damit einhergehend muessen Prozesse, Rollen und auch Geschaeftsmodelle neu durchdacht werden. Denn weitere Herausforderungen stehen im direkten Zusammenhang mit Smart Metering. Das ist zum einen die Rolle des Messstellenbetreibers / Messdienstleisters. Das ist zum anderen der Endnutzer, dem die Rolle des aktiven Marktpartners zugedacht wird. Das ist des Weiteren das Smart Metering als Basistechnologie beispielsweise fuer Smart Grid und Smart Home. Trotz des Handlungsdrucks stehen viele Unternehmen der Energiewirtschaft dem Smart Metering zurueckhaltend gegenueber. Drei gewichtige Gruende werden ins Feld gefuehrt: die Kostenfrage, nicht definierte Standards und die in vielen Bereichen ungeklaerte Gesetzeslage. Demgegenueber bietet das Smart Metering Potenziale fuer Netz und Vertrieb, die es zu nutzen gilt. Die Autoren setzen sich in ihren Beitraegen mit diesen Themen auseinander, zeigen Chancen, aber auch Grenzen des

  11. Experimental and Theoretical Analysis of Headlight Surface Temperature in an Infrared Heated Stress Relieving Oven

    Directory of Open Access Journals (Sweden)

    Mustafa MUTLU

    2016-04-01

    Full Text Available In this study, the IR heated stress relieve oven was experimentally and theoretically examined. In experimental measurements, temperature was measured on headlight surface, placed in IR oven at various conveyor speeds and various distances between IR lamps and headlight surface. In theoretical study, a mathematical model was developed for the headlights surface temperature by using heat transfer theory. The results obtained by the mathematical model and the measurement showed very good agreement with a 6.5 % average error. It is shown that mathematical models can be used to estimate the surface temperatures when the oven is operated under different conditions.

  12. Relieving stress. A short-term support group for home attendants.

    Science.gov (United States)

    Blaine, M

    2000-01-01

    Home attendants (HAs) work in relative isolation, burdened by conflicting demands. This article details an eight-session support group for HAs, designed to explore its effects on their work life. Meeting for hour-and-a-half sessions with no fixed agenda, the group offered members an opportunity to communicate with others in similar situations. Participants reported that the group experience helped relieve stress and made them feel less alone. Other benefits included gaining strategies for coping with difficult situations and learning to set boundaries. Further investigation into the effectiveness of similar groups is suggested.

  13. Best practices for rural smart growth.

    Science.gov (United States)

    2010-07-01

    Smart growth is a development strategy that encompasses economic, environmental and social objectives to manage : the growth of a community. The basic principles of smart growth are to: : Mix land uses. : Take advantage of compact building de...

  14. Smart grids opportunities, developments, and trends

    CERN Document Server

    Ali, A B M Shawkat

    2013-01-01

    This book provides up to date knowledge, research results, and innovations in smart grids spanning design, implementation, analysis and evaluation of smart grid solutions to the challenging problems in all areas of the power industry.

  15. Ecosystem Based Business Model of Smart Grid

    DEFF Research Database (Denmark)

    Lundgaard, Morten Raahauge; Ma, Zheng; Jørgensen, Bo Nørregaard

    2015-01-01

    This paper tries to investigate the ecosystem based business model in a smart grid infrastructure and the potential of value capture in the highly complex macro infrastructure such as smart grid. This paper proposes an alternative perspective to study the smart grid business ecosystem to support...... the infrastructural challenges, such as the interoperability of business components for smart grid. So far little research has explored the business ecosystem in the smart grid concept. The study on the smart grid with the theory of business ecosystem may open opportunities to understand market catalysts. This study...... contributes an understanding of business ecosystem applicable for smart grid. Smart grid infrastructure is an intricate business ecosystem, which have several intentions to deliver the value proposition and what it should be. The findings help to identify and capture value from markets....

  16. Sustainability, Smart Growth, and Landscape Architecture

    Science.gov (United States)

    Sustainability, Smart Growth, and Landscape Architecture is an overview course for landscape architecture students interested in sustainability in landscape architecture and how it might apply to smart growth principles in urban, suburban, and rural areas

  17. Smart dental practice: capitalising on smart mobile technology.

    Science.gov (United States)

    Plangger, K; Bredican, J; Mills, A J; Armstrong, J

    2015-08-14

    To keep pace with consumer adoption of smart mobile devices, such as smartphones and tablets, and the applications ('apps') developed for these devices, dental professionals should consider how this technology could be used to simultaneously improve both patient service experiences and dental practice management. Using U-Commerce as a theoretical lens, this article discusses the potential value of smart mobile technology to the dental practice context, with a particular focus on the unique and customisable capabilities of apps. To take full advantage of this technology, a process is outlined for identifying and designing bespoke dental apps that takes into account the unique advantages of these devices. Dental practices, with increasing financial and competitive pressures, may improve the efficiency and profitability of operations and better manage patients, employees and stakeholders by integrating smart mobile technology.

  18. Smart cities of the future

    Science.gov (United States)

    Batty, M.; Axhausen, K. W.; Giannotti, F.; Pozdnoukhov, A.; Bazzani, A.; Wachowicz, M.; Ouzounis, G.; Portugali, Y.

    2012-11-01

    Here we sketch the rudiments of what constitutes a smart city which we define as a city in which ICT is merged with traditional infrastructures, coordinated and integrated using new digital technologies. We first sketch our vision defining seven goals which concern: developing a new understanding of urban problems; effective and feasible ways to coordinate urban technologies; models and methods for using urban data across spatial and temporal scales; developing new technologies for communication and dissemination; developing new forms of urban governance and organisation; defining critical problems relating to cities, transport, and energy; and identifying risk, uncertainty, and hazards in the smart city. To this, we add six research challenges: to relate the infrastructure of smart cities to their operational functioning and planning through management, control and optimisation; to explore the notion of the city as a laboratory for innovation; to provide portfolios of urban simulation which inform future designs; to develop technologies that ensure equity, fairness and realise a better quality of city life; to develop technologies that ensure informed participation and create shared knowledge for democratic city governance; and to ensure greater and more effective mobility and access to opportunities for urban populations. We begin by defining the state of the art, explaining the science of smart cities. We define six scenarios based on new cities badging themselves as smart, older cities regenerating themselves as smart, the development of science parks, tech cities, and technopoles focused on high technologies, the development of urban services using contemporary ICT, the use of ICT to develop new urban intelligence functions, and the development of online and mobile forms of participation. Seven project areas are then proposed: Integrated Databases for the Smart City, Sensing, Networking and the Impact of New Social Media, Modelling Network Performance

  19. Smart Grid Information Clearinghouse (SGIC)

    Energy Technology Data Exchange (ETDEWEB)

    Rahman, Saifur [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2014-08-31

    Since the Energy Independence and Security Act of 2007 was enacted, there has been a large number of websites that discusses smart grid and relevant information, including those from government, academia, industry, private sector and regulatory. These websites collect information independently. Therefore, smart grid information was quite scattered and dispersed. The objective of this work was to develop, populate, manage and maintain the public Smart Grid Information Clearinghouse (SGIC) web portal. The information in the SGIC website is comprehensive that includes smart grid information, research & development, demonstration projects, technical standards, costs & benefit analyses, business cases, legislation, policy & regulation, and other information on lesson learned and best practices. The content in the SGIC website is logically grouped to allow easily browse, search and sort. In addition to providing the browse and search feature, the SGIC web portal also allow users to share their smart grid information with others though our online content submission platform. The Clearinghouse web portal, therefore, serves as the first stop shop for smart grid information that collects smart grid information in a non-bias, non-promotional manner and can provide a missing link from information sources to end users and better serve users’ needs. The web portal is available at www.sgiclearinghouse.org. This report summarizes the work performed during the course of the project (September 2009 – August 2014). Section 2.0 lists SGIC Advisory Committee and User Group members. Section 3.0 discusses SGIC information architecture and web-based database application functionalities. Section 4.0 summarizes SGIC features and functionalities, including its search, browse and sort capabilities, web portal social networking, online content submission platform and security measures implemented. Section 5.0 discusses SGIC web portal contents, including smart grid 101, smart grid projects

  20. Data privacy for the smart grid

    CERN Document Server

    Herold, Rebecca

    2015-01-01

    The Smart Grid and PrivacyWhat Is the Smart Grid? Changes from Traditional Energy Delivery Smart Grid Possibilities Business Model Transformations Emerging Privacy Risks The Need for Privacy PoliciesPrivacy Laws, Regulations, and Standards Privacy-Enhancing Technologies New Privacy Challenges IOT Big Data What Is the Smart Grid?Market and Regulatory OverviewTraditional Electricity Business SectorThe Electricity Open Market Classifications of Utilities Rate-Making ProcessesElectricity Consumer

  1. Hardware Design of a Smart Meter

    OpenAIRE

    Ganiyu A. Ajenikoko; Anthony A. Olaomi

    2014-01-01

    Smart meters are electronic measurement devices used by utilities to communicate information for billing customers and operating their electric systems. This paper presents the hardware design of a smart meter. Sensing and circuit protection circuits are included in the design of the smart meter in which resistors are naturally a fundamental part of the electronic design. Smart meters provides a route for energy savings, real-time pricing, automated data collection and elimina...

  2. Basic design report of SMART

    International Nuclear Information System (INIS)

    Chang, M. H.; Yeo, J. W.; Zee, Q. S.; Lee, D. J.; Park, K. B.; Koo, I. S.; Kim, H. C.; Kim, J. I.

    2002-03-01

    KAERI has been developing a 330MWt integral reactor, SMART and its application system since 1997. SMART is being developed for use as an energy source for small-scale power generation and seawater desalination. The SMART system can produce portable water of 40.000m 3 /day using the MED-TVC desalination process and about 90MW of electricity. Although the design of SMART is based on the current pressurized water reactor technology, new technologies such as inherent safety and passive safety have been applied, and system simplification and modularization, innovations in manufacturing and installation technologies have been implemented culminating in a design that has enhanced safety and economy, and is environment-friendly. The objective of this design report is to provide the overall information on the basic design of SMART NSSS, and the applied technologies. The information covers mainly NSSS design with some information on the desalination system. For the secondary system, only the information directly related to the coupling with NSSS are covered

  3. A Review of Systems and Technologies for Smart Homes and Smart Grids

    OpenAIRE

    Lobaccaro, Gabriele; Carlucci, Salvatore; Löfström, Erica

    2016-01-01

    In the actual era of smart homes and smart grids, advanced technological systems that allow the automation of domestic tasks are developing rapidly. There are numerous technologies and applications that can be installed in smart homes today. They enable communication between home appliances and users, and enhance home appliances’ automation, monitoring and remote control capabilities. This review article, by introducing the concept of the smart home and the advent of the smart grid, investiga...

  4. Smart Grid Security A Smart Meter-Centric Perspective

    DEFF Research Database (Denmark)

    Vigo, Roberto; Yuksel, Ender; Ramli, Carroline Dewi Puspa Kencana

    2012-01-01

    , leading to what is known as the Smart Grid. The development of this Cyber-Physical System introduces new security issues, thus calling for efforts in studying possible attacks and devising suitable countermeasures. In this paper, we review a generic model for the Smart Grid, and present possible attacks......The electricity grid is a key infrastructure for our society, therefore its security is a critical public concern. This physical system is becoming more and more complex as it is coupled with a cyber layer carrying information about power usage and control instructions for intelligent appliances...

  5. Effects of Moderate Exercise on Relieving Mental Load of Elementary School Teachers

    Directory of Open Access Journals (Sweden)

    Shing-Hong Liu

    2015-01-01

    Full Text Available Long-term endurance exercise could increase activity of parasympathetic nervous and decrease activity of sympathetic nervous at rest. However, previous studies all focused on the effect of endurance training on heart rate variability (HRV for athletes or sedentary subjects. In Taiwan, elementary school teachers teaching and processing the children’s and administrative problems always stand and walk. They will sit down only when they review and correct the students’ home work. Thus, the goal of this study was to elucidate the beneficial effect of moderate intensity exercise on relieving mental load of elementary school teachers. There were 20 participants in the exercise group and another 20 participants in the nonexercise group. The exercising teachers performed 12 weeks of moderate intensity exercise training for an average of 30 minutes per day, 3 times per week. HRV was measured before and after the 4th, 6th, and 12th weeks. The time and frequency domain parameters of HRV all had significant increases between the beginning and after 12 weeks of training. However, the time and frequency domain parameters of HRV in the nonexercise group had significant decreases between the beginning and after 12 weeks of training. The long-term moderate exercises can relieve mental load of elementary school teachers. Moreover, age was the considerable factor affecting HRV in this study.

  6. A study on the mechanical stress relieving and safety assessment without post-weld heat treatment

    International Nuclear Information System (INIS)

    Xu Jijin; Chen Ligong; Ni Chunzhen

    2007-01-01

    For full welded body valve, the temperature of grommet cannot exceed 150 deg. C in order to prevent it from damaging and assure the tightness and the service life of valve. Therefore, post-weld heat treatment (PWHT) cannot be used to relieve the residual stresses. In this study, the effect of the mechanical stress relieving (MSR) treatment on the residual stresses was studied by the finite element method and experimental work. A pressure and time diagram of MSR treatment was established. A two-dimensional axisymmetric finite element model was used to simulate the residual stresses field. Before and after MSR treatment, the residual stresses on the outer surface were measured by the blind hole drilling method. Finally, the fracture toughness behaviors of weld zone (WZ) and heat affected zone (HAZ) were investigated in terms of crack tip opening displacement (CTOD) according to BS7448 and DNV-OS-C401 fracture toughness tests standards. The safety of the valve in active service was assessed without PWHT. Through comparison and analysis, the axial residual stresses and the hoop residual stresses on the outer surface of valve are mainly tensile. The peak value of tensile stress occurs nearer to the outer surface of the valve. MSR treatment can decrease the peak value of axial residual stresses and hoop residual stresses on the outer surface obviously and make the residual stresses distribution more uniform. The safety of the valve in active service is reliable without PWHT

  7. Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions: a randomized controlled trial.

    Science.gov (United States)

    Maenthaisong, Ratree; Chaiyakunapruk, Nathorn; Tiyaboonchai, Waree; Tawatsin, Apiwat; Rojanawiwat, Archawin; Thavara, Usavadee

    2014-02-01

    Trikatu is composed of dried fruits of Piper nigrum L and Piper retrofractum Vahl, and dried rhizomes of Zingiber officinale R. Although this preparation has been used to relieve pruritis, pain, and inflammation for a long time, there is no clinical evidence to confirm its efficacy and safety. Therefore, we performed a double-blind, within person-randomized controlled study of 30 healthy volunteers to determine efficacy and safety of topical Trikatu on mosquito bite reactions. All subjects were bitten by Aedes aegypti laboratory mosquitoes on their forearms and they were randomly assigned arms to apply either Trikatu or reference product on the mosquito bite papule. The main outcome was the difference of papule size reduction at 30 min, measured by a caliper, between the Trikatu and reference arms. Pruritis, redness, pain, and patient satisfaction were assessed at 15, 30, 60, 180, and 360 min as secondary outcomes. There were no significant differences between treatment and reference arms on any outcome at any time of measurement. Trikatu did not show additional effects for relieving mosquito bite reaction as compared with the reference product containing camphor, menthol, and eucalyptus. For further study, it is very important to consider a proper selection of subjects, comparator product, and concentration of extract when Trikatu preparation is investigated. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Smart City Governance: A Local Emergent Perspective

    NARCIS (Netherlands)

    Meijer, Albert

    2016-01-01

    This chapter presents a local emergent perspective on smart city governance. Smart city governance is about using new technologies to develop innovative governance arrangements. Cities all around the world are struggling to find smart solutions to wicked problems and they hope to learn from

  9. Scalable Open Source Smart Grid Simulator (SGSim)

    DEFF Research Database (Denmark)

    Ebeid, Emad Samuel Malki; Jacobsen, Rune Hylsberg; Stefanni, Francesco

    2017-01-01

    . This paper presents an open source smart grid simulator (SGSim). The simulator is based on open source SystemC Network Simulation Library (SCNSL) and aims to model scalable smart grid applications. SGSim has been tested under different smart grid scenarios that contain hundreds of thousands of households...

  10. Ontologies for commitment-based smart contracts

    NARCIS (Netherlands)

    de Kruijff, Joost; Weigand, Hans; Panetto, H; Debruyne, C.; Gaaloul, W.; Papazoglou, M.; Paschke, A.; Ardagna, C.A.; Meersman, R.

    2017-01-01

    Smart contracts gain rapid exposure since the inception of blockchain technology. Yet there is no unified ontology for smart contracts. Being categorized as coded contracts or substitutes of conventional legal contracts, there is a need to reduce the conceptual ambiguity of smart contracts. We

  11. Creating Smart-er Cities: An Overview

    Science.gov (United States)

    Allwinkle, Sam; Cruickshank, Peter

    2011-01-01

    The following offers an overview of what it means for cities to be "smart." It draws the supporting definitions and critical insights into smart cities from a series of papers presented at the 2009 Trans-national Conference on Creating Smart(er) Cities. What the papers all have in common is their desire to overcome the all too often…

  12. Rancangbangun Smart Green House untuk Tanaman Hidroponik

    OpenAIRE

    Syam, Rafiuddin

    2011-01-01

    Penelitian ini bertujuan merancang sistem kendali dan membuat manipulator smart green house. Metode penelitian yang dilakukan adalah eksperimen pada model smart green house. Dalam sistem ini mengggunakan mikrokontroller sebagai antar muka untuk melakukan peregerakan manipulator dalam sistem secara integritas. Smart greenhouse menggunakan sensor suhu, cahaya dan mikrokontroller yang digunakan adalah ATMEGA 8535. Torsi motor digunakan untuk mengangkat dan mendorong jendela dengan lengan manipul...

  13. Smart Mobility Stakeholders - Curating Urban Data & Models

    Energy Technology Data Exchange (ETDEWEB)

    Sperling, Joshua [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-01

    This presentation provides an overview of the curation of urban data and models through engaging SMART mobility stakeholders. SMART Mobility Urban Science Efforts are helping to expose key data sets, models, and roles for the U.S. Department of Energy in engaging across stakeholders to ensure useful insights. This will help to support other Urban Science and broader SMART initiatives.

  14. Streamlining Smart Meter Data Analytics

    DEFF Research Database (Denmark)

    Liu, Xiufeng; Nielsen, Per Sieverts

    2015-01-01

    of the so-called big data possible. This can improve energy management, e.g., help utilities improve the management of energy and services, and help customers save money. As this regard, the paper focuses on building an innovative software solution to streamline smart meter data analytic, aiming at dealing......Today smart meters are increasingly used in worldwide. Smart meters are the advanced meters capable of measuring customer energy consumption at a fine-grained time interval, e.g., every 15 minutes. The data are very sizable, and might be from different sources, along with the other social......-economic metrics such as the geographic information of meters, the information about users and their property, geographic location and others, which make the data management very complex. On the other hand, data-mining and the emerging cloud computing technologies make the collection, management, and analysis...

  15. Co-designing smart tourism

    DEFF Research Database (Denmark)

    Liburd, Janne J.; Nielsen, Tanja K.; Heape, Chris

    2017-01-01

    Emerging theories of smart tourism are chiefly concerned with how Internet Communication Technology and Big Data can influence marketing, product and destination development. The risk being that an overt focus on formal outcomes, namely technology, products and services, diverts attention from how...... things and operations are actually achieved. This paper challenges the notions of smart and value co-creation by introducing tourism co-design as a learning and experiment driven development process. Tourism co-design leverages the communicative interaction between people and enables tourism operators...... to change their practices. Based on fieldwork in the northern part of Denmark we explore how smart tourism can become smarter through tourism co-design processes. We argue that a shift is needed from: How can we efficiently achieve a more or less known goal? To: How can we effectively explore and give sense...

  16. Smart Phones and their Substitutes

    DEFF Research Database (Denmark)

    Bødker, Mads; Gimpel, Gregory; Hedman, Jonas

    2009-01-01

    Drawing on data from a longitudinal field study, this paper investigates the influence of existing, better and stand-alone technology substitutes on the use of smart phones. By applying prospect theory, media richness theory, and business model literature, the purpose of this paper is to improve...... our understanding of the role of substitutes, device content fit issues, and implications for business models by asking the question: What is an effective business model to address the relationship between user preference and the fit of the smart phone and everyday task? The field study data suggest...... the need for business models to recognize that adoption decisions are reference-dependent and strongly influenced by the fit between task and smart phone....

  17. Aging well with smart technology.

    Science.gov (United States)

    Cheek, Penny; Nikpour, Linda; Nowlin, Heather D

    2005-01-01

    As baby-boomers age, the need for long-term nursing care services increases. In the future, there will simply not be enough long-term care facilities to accommodate all of these patients. In addition, many people prefer to grow old at home, a concept known as aging-in-place. Smart home technology facilities aging-in-place by assisting patients with emergency assistance, fall prevention/detection, reminder systems, medication administration and assistance for those with hearing, visual or cognitive impairments. Benefits include making aging-in-place a reality, continuous monitoring, and improved psychosocial effects. Concerns of this technology include cost, availability of technology, retrofitting complications, and potential inappropriate use of the technology. Overall, the concept of smart homes is gaining in popularity and will expand the role of the nurse in the future. It is important for all nurses to understand how their practices will be transformed as smart homes become a reality for the aging population.

  18. Smart systems integration and simulation

    CERN Document Server

    Poncino, Massimo; Pravadelli, Graziano

    2016-01-01

    This book-presents new methods and tools for the integration and simulation of smart devices. The design approach described in this book explicitly accounts for integration of Smart Systems components and subsystems as a specific constraint. It includes methodologies and EDA tools to enable multi-disciplinary and multi-scale modeling and design, simulation of multi-domain systems, subsystems and components at all levels of abstraction, system integration and exploration for optimization of functional and non-functional metrics. By covering theoretical and practical aspects of smart device design, this book targets people who are working and studying on hardware/software modelling, component integration and simulation under different positions (system integrators, designers, developers, researchers, teachers, students etc.). In particular, it is a good introduction to people who have interest in managing heterogeneous components in an efficient and effective way on different domains and different abstraction l...

  19. SMART POWER TURBINE

    Energy Technology Data Exchange (ETDEWEB)

    Nirm V. Nirmalan

    2003-11-01

    Gas turbines are the choice technology for high-performance power generation and are employed in both simple and combined cycle configurations around the world. The Smart Power Turbine (SPT) program has developed new technologies that are needed to further extend the performance and economic attractiveness of gas turbines for power generation. Today's power generation gas turbines control firing temperatures indirectly, by measuring the exhaust gas temperature and then mathematically calculating the peak combustor temperatures. But temperatures in the turbine hot gas path vary a great deal, making it difficult to control firing temperatures precisely enough to achieve optimal performance. Similarly, there is no current way to assess deterioration of turbine hot-gas-path components without shutting down the turbine. Consequently, maintenance and component replacements are often scheduled according to conservative design practices based on historical fleet-averaged data. Since fuel heating values vary with the prevalent natural gas fuel, the inability to measure heating value directly, with sufficient accuracy and timeliness, can lead to maintenance and operational decisions that are less than optimal. GE Global Research Center, under this Smart Power Turbine program, has developed a suite of novel sensors that would measure combustor flame temperature, online fuel lower heating value (LHV), and hot-gas-path component life directly. The feasibility of using the ratio of the integrated intensities of portions of the OH emission band to determine the specific average temperature of a premixed methane or natural-gas-fueled combustion flame was demonstrated. The temperature determined is the temperature of the plasma included in the field of view of the sensor. Two sensor types were investigated: the first used a low-resolution fiber optic spectrometer; the second was a SiC dual photodiode chip. Both methods worked. Sensitivity to flame temperature changes was

  20. Hiring for smarts.

    Science.gov (United States)

    Menkes, Justin

    2005-11-01

    Yes, it's nice when a leader is charismatic and confident. And a great resume can tell you a lot about a person's knowledge and experience. But such assets are no substitute for sheer business intelligence, and they reveal very little about a leader's ability to consistently reach the "right" answer. How can hiring managers flag individuals with such smarts? Historically, the only reliable measure of brainpower has been the standard IQ test, which is rarely used in business settings because of the specific subjects it tests for-math, reading, and spatial reasoning-and because of its multiple-choice format. Despite its shortcomings, the standard IQ test is still a better predictor of managerial success than any other assessment tool companies currently use, Justin Menkes argues. It's true that there isn't a version of IQ testing that applies to the corporate world, but in rejecting IQ tests altogether, hiring managers have thwarted their own attempts to identify true business stars. The author defines the specific subjects that make up "executive intelligence"-namely, accomplishing tasks, working with people, and judging oneself. He describes how to formulate questions to test job candidates for their mastery of these subjects, offering several examples based on real situations. Knowledge questions, such as those used in standard behavioral interviews, require people to recite what they have learned or experienced; intelligence questions call for individuals to demonstrate their abilities. Therefore, the questions in an executive intelligence test shouldn't require specific industry expertise or experience; any knowledge they call for must be rudimentary and common to all executives. And the questions should not be designed to ask whether the candidate has a particular skill; they should be configured so that the candidate will have to demonstrate that skill in the course of answering them.

  1. Smart Sensors for Launch Vehicles

    Science.gov (United States)

    Ray, Sabooj; Mathews, Sheeja; Abraham, Sheena; Pradeep, N.; Vinod, P.

    2017-12-01

    Smart Sensors bring a paradigm shift in the data acquisition mechanism adopted for launch vehicle telemetry system. The sensors integrate signal conditioners, digitizers and communication systems to give digital output from the measurement location. Multiple sensors communicate with a centralized node over a common digital data bus. An in-built microcontroller gives the sensor embedded intelligence to carry out corrective action for sensor inaccuracies. A smart pressure sensor has been realized and flight-proven to increase the reliability as well as simplicity in integration so as to obtain improved data output. Miniaturization is achieved by innovative packaging. This work discusses the construction, working and flight performance of such a sensor.

  2. Smart wheelchairs: A literature review.

    Science.gov (United States)

    Simpson, Richard C

    2005-01-01

    Several studies have shown that both children and adults benefit substantially from access to a means of independent mobility. While the needs of many individuals with disabilities can be satisfied with traditional manual or powered wheelchairs, a segment of the disabled community finds it difficult or impossible to use wheelchairs independently. To accommodate this population, researchers have used technologies originally developed for mobile robots to create "smart wheelchairs." Smart wheelchairs have been the subject of research since the early 1980s and have been developed on four continents. This article presents a summary of the current state of the art and directions for future research.

  3. SODA: Smart Objects, Dumb Archives

    Science.gov (United States)

    Nelson, Michael L.; Maly, Kurt; Zubair, Mohammad; Shen, Stewart N. T.

    2004-01-01

    We present the Smart Object, Dumb Archive (SODA) model for digital libraries (DLs). The SODA model transfers functionality traditionally associated with archives to the archived objects themselves. We are exploiting this shift of responsibility to facilitate other DL goals, such as interoperability, object intelligence and mobility, and heterogeneity. Objects in a SODA DL negotiate presentation of content and handle their own terms and conditions. In this paper we present implementations of our smart objects, buckets, and our dumb archive (DA). We discuss the status of buckets and DA and how they are used in a variety of DL projects.

  4. Smart Grid enabled heat pumps

    DEFF Research Database (Denmark)

    Carmo, Carolina; Detlefsen, Nina; Nielsen, Mads Pagh

    2014-01-01

    The transition towards a 100 % fossil-free energy system, while achieving extreme penetration levels of intermittent wind and solar power in electricity generation, requires demand-side technologies that are smart (intermittency-friendly) and efficient. The integration of Smart Grid enabling...... with an empirical study in order to achieve a number of recommendations with respect to technology concepts and control strategies that would allow residential vapor-compression heat pumps to support large-scale integration of intermittent renewables. The analysis is based on data gathered over a period of up to 3...

  5. Smart Grid Security. White Paper

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-09-15

    One of the biggest concerns for smart grid developers is cyber security due to the reliance on IT communication networks. While the current grid is not immune to energy theft, fraud and malicious cyber-attacks, the smart grid poses new security issues. It is more likely now that theft, malicious attack and fraud will be committed by people working remotely from a laptop several miles away, even in a different country, than someone physically manipulating meters. This makes it difficult to predict where attacks will come from.

  6. IBM SmartCloud essentials

    CERN Document Server

    Schouten, Edwin

    2013-01-01

    A practical, user-friendly guide that provides an introduction to cloud computing using IBM SmartCloud, along with a thorough understanding of resource management in a cloud environment.This book is great for anyone who wants to get a grasp of what cloud computing is and what IBM SmartCloud has to offer. If you are an IT specialist, IT architect, system administrator, or a developer who wants to thoroughly understand the cloud computing resource model, this book is ideal for you. No prior knowledge of cloud computing is expected.

  7. Smart Grids and Distributed Generation

    Directory of Open Access Journals (Sweden)

    Dorin BICĂ

    2018-06-01

    Full Text Available This paper describes the main characteristics of Smart Grids and distributed generation. Smart Grids can be defined as a modernization of the power system so it monitors, protects and automatically optimizes the operation of its interconnected elements (power plants, transmission and distribution system, industrial and residential loads. Distributed generation (DG refers to the production of electricity near the consumption place using renewable energy sources. A load flow analysis is performed for the IEEE14 system in which a DG source (a 5MW wind turbine is added that is on-grid or off-grid. The power losses are determined for these two cases.

  8. Smart query answering for marine sensor data.

    Science.gov (United States)

    Shahriar, Md Sumon; de Souza, Paulo; Timms, Greg

    2011-01-01

    We review existing query answering systems for sensor data. We then propose an extended query answering approach termed smart query, specifically for marine sensor data. The smart query answering system integrates pattern queries and continuous queries. The proposed smart query system considers both streaming data and historical data from marine sensor networks. The smart query also uses query relaxation technique and semantics from domain knowledge as a recommender system. The proposed smart query benefits in building data and information systems for marine sensor networks.

  9. Evaluation of Smart Gun Technologies preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, D.R.

    1996-01-01

    The Smart Gun Technology Project has a goal to eliminate the capability of an unauthorized user from firing a law enforcement officer`s firearm by implementing {open_quote}smart{close_quote} technologies. Smart technologies are those that can in some manner identify an officer. This report will identify, describe, and grade various technologies as compared to the requirements that were obtained from officers. This report does not make a final recommendation for a smart gun technology, nor does it give the complete design of a smart gun system.

  10. Communication and Networking in Smart Grids

    CERN Document Server

    Xiao, Yang

    2012-01-01

    Appropriate for researchers, practitioners, and students alike, Communication and Networking in Smart Grids presents state-of-the-art approaches and novel technologies for communication networks in smart grids. It explains how contemporary grid networks are developed and deployed and presents a collection of cutting-edge advances to help improve current practice. Prominent researchers working on smart grids and in related fields around the world explain the fundamental aspects and applications of smart grids. Describing the role that communication and networking will play in future smart grids

  11. Smart Query Answering for Marine Sensor Data

    Directory of Open Access Journals (Sweden)

    Paulo de Souza

    2011-03-01

    Full Text Available We review existing query answering systems for sensor data. We then propose an extended query answering approach termed smart query, specifically for marine sensor data. The smart query answering system integrates pattern queries and continuous queries. The proposed smart query system considers both streaming data and historical data from marine sensor networks. The smart query also uses query relaxation technique and semantics from domain knowledge as a recommender system. The proposed smart query benefits in building data and information systems for marine sensor networks.

  12. Detection of Social Interaction in Smart Spaces.

    Science.gov (United States)

    Cook, Diane J; Crandall, Aaron; Singla, Geetika; Thomas, Brian

    2010-02-01

    The pervasive sensing technologies found in smart environments offer unprecedented opportunities for monitoring and assisting the individuals who live and work in these spaces. An aspect of daily life that is important for one's emotional and physical health is social interaction. In this paper we investigate the use of smart environment technologies to detect and analyze interactions in smart spaces. We introduce techniques for collect and analyzing sensor information in smart environments to help in interpreting resident behavior patterns and determining when multiple residents are interacting. The effectiveness of our techniques is evaluated using two physical smart environment testbeds.

  13. CASAS: A Smart Home in a Box.

    Science.gov (United States)

    Cook, Diane J; Crandall, Aaron S; Thomas, Brian L; Krishnan, Narayanan C

    2013-07-01

    While the potential benefits of smart home technology are widely recognized, a lightweight design is needed for the benefits to be realized at a large scale. We introduce the CASAS "smart home in a box", a lightweight smart home design that is easy to install and provides smart home capabilities out of the box with no customization or training. We discuss types of data analysis that have been performed by the CASAS group and can be pursued in the future by using this approach to designing and implementing smart home technologies.

  14. Smart Distribution Boxes, Complete Energy Management

    Energy Technology Data Exchange (ETDEWEB)

    Platise, Uros

    2010-09-15

    Present households demand side management implementations are turning conventional appliances into smart ones to support auto demand (AutoDR) response function. Present concept features a direct link between the power meters and appliances. In this paper new concept and example of implementation of a so-called Smart Distribution Box (SmartDB) is represented for complete energy and power management. SmartDBs, as an intermediate layer, are extending smart grid power meter functionality to support AutoDR with fast and guaranteed response times, distributed power sources, and besides provide full control over energy management and extra safety functions to the consumers.

  15. Smart grid standards specifications, requirements, and technologies

    CERN Document Server

    Sato, Takuro; Duan, Bin; Macuha, Martin; Zhou, Zhenyu; Wu, Jun; Tariq, Muhammad; Asfaw, Solomon A

    2015-01-01

    With numerous existing Smart Grid standards, it is clear that governments and industrial organizations world-wide have understood and acknowledged the critical role they play. This timely book is a useful guide for Smart Grid professionals in easily classifying fundamental Smart Grid standards, and to quickly find the building blocks they need to analyse and implement a Smart Grid system. The standards are organized in a systematic manner that aids identification, according to grid requirements. It also covers broader Smart Grid areas including, but not limited to, the following: A fully c

  16. Smart cities, smart lights. Digital signane and the city experience

    OpenAIRE

    Fiori, Giovanni

    2012-01-01

    This article is about the experience of light in the smart and digital city or, in other words, the existing and widening use of visual digital signane in the urban environment, open air and in public places. This research focuses on where in towns this digital "contamination" is more visible and accessible, i.e. in shopping districts.

  17. Smart Grids. Innovators talking; Smart Grids. Innovators aan het woord

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-02-15

    Qualitative studies have been conducted of the results of completed projects focused on energy innovation, spread over the seven themes of the top sector Energy: Energy saving in industry, Energy conservation in the built environment, Gas, Bio-energy, Smart grids, Offshore Wind, Solar PV. This provides insight into the follow-up activities and lessons of some EOS (Energy Research Subsidy) completed projects with the aim to inspire, connect and strengthen the TKIs (Topconsortia for Knowledge and Innovation) and individual companies and researchers working on energy innovation. This report concerns the research on Smart Grids [Dutch] Er is een kwalitatief onderzoek uitgevoerd naar de resultaten van afgeronde projecten gericht op energie-innovatie, verdeeld over de zeven thema's van de topsector Energie: Energiebesparing in de industrie; Energiebesparing in de gebouwde omgeving; Gas; Bio-energie; Smart grids; Wind op zee; Zon-pv. Daarmee wordt inzicht gegeven in de vervolgactiviteiten en lessen van een aantal afgesloten EOS-projecten (Energie Onderzoek Subsidie) met het oog op het inspireren, verbinden en versterken van de TKI's (Topconsortia voor Kennis en Innovatie) en individuele bedrijven en onderzoekers die werken aan energie-innovatie. Dit rapport betreft het onderzoek naar Smart Grids.

  18. Ten questions concerning integrating smart buildings into the smart grid

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, Thomas M.; Boudreau, Marie-Claude; Helsen, Lieve; Henze, Gregor; Mohammadpour, Javad; Noonan, Doug; Patteeuw, Dieter; Pless, Shanti; Watson, Richard T.

    2016-11-01

    Recent advances in information and communications technology (ICT) have initiated development of a smart electrical grid and smart buildings. Buildings consume a large portion of the total electricity production worldwide, and to fully develop a smart grid they must be integrated with that grid. Buildings can now be 'prosumers' on the grid (both producers and consumers), and the continued growth of distributed renewable energy generation is raising new challenges in terms of grid stability over various time scales. Buildings can contribute to grid stability by managing their overall electrical demand in response to current conditions. Facility managers must balance demand response requests by grid operators with energy needed to maintain smooth building operations. For example, maintaining thermal comfort within an occupied building requires energy and, thus an optimized solution balancing energy use with indoor environmental quality (adequate thermal comfort, lighting, etc.) is needed. Successful integration of buildings and their systems with the grid also requires interoperable data exchange. However, the adoption and integration of newer control and communication technologies into buildings can be problematic with older legacy HVAC and building control systems. Public policy and economic structures have not kept up with the technical developments that have given rise to the budding smart grid, and further developments are needed in both technical and non-technical areas.

  19. Smart Grids. Innovators talking; Smart Grids. Innovators aan het woord

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-02-15

    Qualitative studies have been conducted of the results of completed projects focused on energy innovation, spread over the seven themes of the top sector Energy: Energy saving in industry, Energy conservation in the built environment, Gas, Bio-energy, Smart grids, Offshore Wind, Solar PV. This provides insight into the follow-up activities and lessons of some EOS (Energy Research Subsidy) completed projects with the aim to inspire, connect and strengthen the TKIs (Topconsortia for Knowledge and Innovation) and individual companies and researchers working on energy innovation. This report concerns the research on Smart Grids [Dutch] Er is een kwalitatief onderzoek uitgevoerd naar de resultaten van afgeronde projecten gericht op energie-innovatie, verdeeld over de zeven thema's van de topsector Energie: Energiebesparing in de industrie; Energiebesparing in de gebouwde omgeving; Gas; Bio-energie; Smart grids; Wind op zee; Zon-pv. Daarmee wordt inzicht gegeven in de vervolgactiviteiten en lessen van een aantal afgesloten EOS-projecten (Energie Onderzoek Subsidie) met het oog op het inspireren, verbinden en versterken van de TKI's (Topconsortia voor Kennis en Innovatie) en individuele bedrijven en onderzoekers die werken aan energie-innovatie. Dit rapport betreft het onderzoek naar Smart Grids.

  20. Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases

    Directory of Open Access Journals (Sweden)

    Darkovska-Serafimovska M

    2018-04-01

    Full Text Available Marija Darkovska-Serafimovska,1 Tijana Serafimovska,2 Zorica Arsova-Sarafinovska,1 Sasho Stefanoski,3 Zlatko Keskovski,3 Trajan Balkanov4 1Department of Pharmacology, Faculty of Medical Sciences, Goce Delcev University, Stip, Republic of Macedonia; 2Faculty of Pharmacy, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia; 3NYSK Holdings, Skopje, Republic of Macedonia; 4Department of Pharmacology and Toxicology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia Purpose: The aim of this review was to assess the efficacy of cannabis preparations for relieving pain in patients with malignant diseases, through a systematic review of randomized controlled trials (RCTs, which were predominantly double-blind trials that compared cannabis preparation to a placebo.Methods: An electronic search of all literature published until June 2017 was made in MEDLINE/PubMed, Embase, The Cochrane Controlled Trials Register and specific web pages devoted to cannabis.Results: Fifteen of the 18 trials demonstrated a significant analgesic effect of cannabinoids as compared to placebo. The most commonly reported adverse effects were generally well tolerated, mild to moderate. The main side effects were drowsiness, nausea, vomiting and dry mouth. There is evidence that cannabinoids are safe and modestly effective in neuropathic pain and also for relieving pain in patients with malignant diseases. The proportion of “responders” (patients who at the end of 2 weeks of treatment reported ≥30% reduction in pain intensity on a scale of 0–10, which is considered to be clinically important was 43% in comparison with placebo (21%. Conclusion: The target dose for relieving pain in patients with malignant diseases is most likely about 10 actuations per day, which is about 27 mg tetrahydrocannabinol (THC and 25 mg cannabidiol (CBD, and the highest approved recommended dose is 12 actuations per day (32 mg THC

  1. 3rd international KES conference on Smart Education and Smart e-Learning

    CERN Document Server

    Howlett, Robert; Jain, Lakhmi

    2016-01-01

    This book contains the contributions presented at the 3rd international KES conference on Smart Education and Smart e-Learning, which took place in Puerto de la Cruz, Tenerife, Spain, June 15-17, 2016. It contains a total of 56 peer-reviewed book chapters that are grouped into several parts: Part 1 - Smart University: Conceptual Modeling, Part 2 – Smart Education: Research and Case Studies, Part 3 – Smart e-Learning, Part 4 – Smart Education: Software and Hardware Systems, and Part 5 – Smart Technology as a Resource to Improve Education and Professional Training. We believe that the book will serve as a useful source of research data and valuable information for faculty, scholars, Ph.D. students, administrators, and practitioners - those who are interested in innovative areas of smart education and smart e-learning. .

  2. 2nd international KES conference on Smart Education and Smart e-Learning

    CERN Document Server

    Howlett, Robert; Jain, Lakhmi

    2015-01-01

    This book contains the contributions presented at the 2nd international KES conference on Smart Education and Smart e-Learning, which took place in Sorrento, Italy, June 17-19, 2015. It contains a total of 45 peer-reviewed book chapters that are grouped into several parts: Part 1 - Smart Education, Part 2 – Smart Educational Technology, Part 3 – Smart e-Learning, Part 4 – Smart Professional Training and Teachers’ Education, and Part 5 – Smart Teaching and Training related Topics.  This book can be a useful source of research data and valuable information for faculty, scholars, Ph.D. students, administrators, and practitioners  - those who are interested in innovative areas of smart education and smart e-learning.  .

  3. Complex IoT Systems as Enablers for Smart Homes in a Smart City Vision

    DEFF Research Database (Denmark)

    Lynggaard, Per; Skouby, Knud Erik

    2016-01-01

    The world is entering a new era, where Internet-of-Things (IoT), smart homes, and smart cities will play an important role in meeting the so-called big challenges. In the near future, it is foreseen that the majority of the world’s population will live their lives in smart homes and in smart cities...... the “smart” vision. This paper proposes a specific solution in the form of a hierarchical layered ICT based infrastructure that handles ICT issues related to the “big challenges” and seamlessly integrates IoT, smart homes, and smart city structures into one coherent unit. To exemplify benefits......% of the wastewater energy in a smart residential building. By letting the smart city infrastructure coordinate and control the harvest time and duration, it is possible to achieve considerable energy savings in the smart homes, and it is possible to reduce the peak-load for district heating plants....

  4. Gamification in the context of smart cities

    Science.gov (United States)

    Zica, M. R.; Ionica, A. C.; Leba, M.

    2018-01-01

    The recent emergence of smart cities is highly supported by the development of IT and IoT technologies. Nevertheless, a smart city needs to be built to meet the needs and requirements of its citizens. In order to build a smart city it is necessary to understand the benefits of such a city. A smart city is, beyond technology, populated by people. A smart city can be raised by its citizens’ contribution, and gamification is the means to motivate them. In this paper we included gamification techniques in the stage of capturing the citizens’ requirements for building a smart city. The system proposed in the paper is to create an application that allows the building of a virtual smart city customized by each user. From this virtual city, the most relevant features are extracted.

  5. Metacognitive components in smart learning environment

    Science.gov (United States)

    Sumadyo, M.; Santoso, H. B.; Sensuse, D. I.

    2018-03-01

    Metacognitive ability in digital-based learning process helps students in achieving learning goals. So that digital-based learning environment should make the metacognitive component as a facility that must be equipped. Smart Learning Environment is the concept of a learning environment that certainly has more advanced components than just a digital learning environment. This study examines the metacognitive component of the smart learning environment to support the learning process. A review of the metacognitive literature was conducted to examine the components involved in metacognitive learning strategies. Review is also conducted on the results of study smart learning environment, ranging from design to context in building smart learning. Metacognitive learning strategies certainly require the support of adaptable, responsive and personalize learning environments in accordance with the principles of smart learning. The current study proposed the role of metacognitive component in smart learning environment, which is useful as the basis of research in building environment in smart learning.

  6. Smart sensing surveillance system

    Science.gov (United States)

    Hsu, Charles; Chu, Kai-Dee; O'Looney, James; Blake, Michael; Rutar, Colleen

    2010-04-01

    Unattended ground sensor (UGS) networks have been widely used in remote battlefield and other tactical applications over the last few decades due to the advances of the digital signal processing. The UGS network can be applied in a variety of areas including border surveillance, special force operations, perimeter and building protection, target acquisition, situational awareness, and force protection. In this paper, a highly-distributed, fault-tolerant, and energyefficient Smart Sensing Surveillance System (S4) is presented to efficiently provide 24/7 and all weather security operation in a situation management environment. The S4 is composed of a number of distributed nodes to collect, process, and disseminate heterogeneous sensor data. Nearly all S4 nodes have passive sensors to provide rapid omnidirectional detection. In addition, Pan- Tilt- Zoom- (PTZ) Electro-Optics EO/IR cameras are integrated to selected nodes to track the objects and capture associated imagery. These S4 camera-connected nodes will provide applicable advanced on-board digital image processing capabilities to detect and track the specific objects. The imaging detection operations include unattended object detection, human feature and behavior detection, and configurable alert triggers, etc. In the S4, all the nodes are connected with a robust, reconfigurable, LPI/LPD (Low Probability of Intercept/ Low Probability of Detect) wireless mesh network using Ultra-wide band (UWB) RF technology, which can provide an ad-hoc, secure mesh network and capability to relay network information, communicate and pass situational awareness and messages. The S4 utilizes a Service Oriented Architecture such that remote applications can interact with the S4 network and use the specific presentation methods. The S4 capabilities and technologies have great potential for both military and civilian applications, enabling highly effective security support tools for improving surveillance activities in densely crowded

  7. Switchable Materials for Smart Windows.

    Science.gov (United States)

    Wang, Yang; Runnerstrom, Evan L; Milliron, Delia J

    2016-06-07

    This article reviews the basic principles of and recent developments in electrochromic, photochromic, and thermochromic materials for applications in smart windows. Compared with current static windows, smart windows can dynamically modulate the transmittance of solar irradiation based on weather conditions and personal preferences, thus simultaneously improving building energy efficiency and indoor human comfort. Although some smart windows are commercially available, their widespread implementation has not yet been realized. Recent advances in nanostructured materials provide new opportunities for next-generation smart window technology owing to their unique structure-property relations. Nanomaterials can provide enhanced coloration efficiency, faster switching kinetics, and longer lifetime. In addition, their compatibility with solution processing enables low-cost and high-throughput fabrication. This review also discusses the importance of dual-band modulation of visible and near-infrared (NIR) light, as nearly 50% of solar energy lies in the NIR region. Some latest results show that solution-processable nanostructured systems can selectively modulate the NIR light without affecting the visible transmittance, thus reducing energy consumption by air conditioning, heating, and artificial lighting.

  8. Smart ampholytic ABC block copolypeptide

    Czech Academy of Sciences Publication Activity Database

    Schlaad, H.; Sun, J.; Černoch, Peter; Ruokolainen, J.

    2017-01-01

    Roč. 254, 20 August (2017), s. 79 ISSN 0065-7727. [ACS National Meeting & Exposition /254./. 20.08.2017-24.08.2017, Washington] Institutional support: RVO:61389013 Keywords : block copolypeptide * smart ampholytic Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science

  9. The smart grid research network

    DEFF Research Database (Denmark)

    Troi, Anders; Jørgensen, Bo Nørregaard; Larsen, Emil Mahler

    2013-01-01

    Grid Network’s recommendations’, which relate to strengthening and marketing the research infrastructure that will position Denmark as the global hub for Smart Grid development; strengthening basic research into the complex relationships in electric systems with large quantities of independent parties...

  10. Smart Grid Control and Communication

    DEFF Research Database (Denmark)

    Ciontea, Catalin-Iosif; Pedersen, Rasmus; Kristensen, Thomas le Fevre

    2015-01-01

    to the reliability due to the stochastic behavior found in such networks. Therefore, key concepts are presented in this paper targeting the support of proper smart grid control in these network environments and its Real-Time Hardware-In-the Loop (HIL) verification. An overview on the required Information...

  11. Designing Smart Charter School Caps

    Science.gov (United States)

    Dillon, Erin

    2010-01-01

    In 2007, Andrew J. Rotherham proposed a new approach to the contentious issue of charter school caps, the statutory limits on charter school growth in place in several states. Rotherham's proposal, termed "smart charter school caps," called for quality sensitive caps that allow the expansion of high-performing charter schools while also…

  12. Smart Houses and Uncomfortable Homes.

    Science.gov (United States)

    Alm, Norman; Arnott, John

    2015-01-01

    In order for smart houses to achieve acceptance from potential beneficiaries they will need to match the users' expectation that their house is also their home, with the sense of privacy and control that this implies. Designers of this technology will need to be aware of findings in this regard from fields such as architecture and design ethnography.

  13. Smart Home Wireless Sensor Nodes

    DEFF Research Database (Denmark)

    Lynggaard, Per

    . This paper introduces an approach that considerably lowers the wireless sensor node power consumption and the amount of transmitted sensor events. It uses smart objects that include artificial intelligence to efficiently process the sensor event on location and thereby saves the costly wireless...

  14. Conducted interference on smart meters

    NARCIS (Netherlands)

    Keyer, Cornelis H.A.; Leferink, Frank

    2017-01-01

    The increasing conducted interference caused by modern electronic equipment is causing more problems for electronic, or static, energy meters. These meters are called smart meters when equipped with a communication link, and are replacing the conventional electromechanical meters. It is known that

  15. Privacy concerns in smart cities

    NARCIS (Netherlands)

    E.A. van Zoonen (Liesbet)

    2016-01-01

    textabstractIn this paper a framework is constructed to hypothesize if and how smart city technologies and urban big data produce privacy concerns among the people in these cities (as inhabitants, workers, visitors, and otherwise). The framework is built on the basis of two recurring dimensions in

  16. Business case for smart homes

    NARCIS (Netherlands)

    Franck, E.; Nauta, J.; Haan, R. de

    2016-01-01

    The application of home automation in “smart homes” has been successful from a technological point of view. In practice, however, few projects seem able to survive after the initial financing period has ended, failing to establish a positive business case. This chapter addresses why the positive

  17. Smart lighting using LED luminaries

    NARCIS (Netherlands)

    Bhardwaj, S.; Ozcelebi, T.; Lukkien, J.J.

    2010-01-01

    The target of a smart lighting system is to control light sources in an environment (e.g. home, office) adaptively according to user contexts and preferences. Literature work in this area focuses on traditional light sources such as incandescent and fluorescent lights, whereas this paper takes a

  18. Stability Studies of a New Design Au/Pt Thermocouple Without a Strain Relieving Coil

    Science.gov (United States)

    Jahan, Ferdouse; Ballico, Mark

    2007-12-01

    The performance of a simple, new design Au/Pt thermocouple developed by NMIA is assessed. This thermocouple is proposed as a more accurate replacement, over the temperature range from 0 to 1,000°C, for the commonly used Type R and S industrial transfer standards, in a robust form familiar to industrial calibration laboratories. Due to the significantly different thermal expansions of the Au and Pt thermoelements, reported designs of the Au/Pt thermocouple incorporate a strain-relieving coil or bridge at the thermocouple junction. As the strain relieving coil is mechanically delicate, these thermocouples are usually mounted in a protective quartz tube assembly, like a standard platinum resistance thermometer (SPRT). Although providing uncertainties at the mK level, they are more delicate than the commonly used Type R and S thermocouples. A new and simple design of the Au/Pt thermocouple was developed in which the differential thermal expansion between Au and Pt is accommodated in the thermocouple leads, facilitated by a special head design. The resulting thermocouple has the appearance and robustness of the traditional Type R and S thermocouples, while retaining stability better than 10 mK up to 961°C. Three thermocouples of this design were calibrated at fixed points and by comparison to SPRTs in a stirred salt bath. In order to assess possible impurity migration, strain effects, and mechanical robustness, sequences of heat treatment up to a total of 500 h together with over 50 thermal cycles from 900°C to ambient were performed. The effect of these treatments on the calibration was assessed, demonstrating the sensors to be robust and stable to better than 10 mK. The effects on the measured inhomogeneity of the thermocouple were assessed using the NMIA thermocouple scanning bath.

  19. DOCUMENTATION AND DETECTION OF COLOUR CHANGES OF BAS RELIEVES USING CLOSE RANGE PHOTOGRAMMETRY

    Directory of Open Access Journals (Sweden)

    E. S. Malinverni

    2017-05-01

    Full Text Available The digitization of complex buildings, findings or bas relieves can strongly facilitate the work of archaeologists, mainly for in depth analysis tasks. Notwithstanding, whether new visualization techniques ease the study phase, a classical naked-eye approach for determining changes or surface alteration could bring towards several drawbacks. The research work described in these pages is aimed at providing experts with a workflow for the evaluation of alterations (e.g. color decay or surface alterations, allowing a more rapid and objective monitoring of monuments. More in deep, a pipeline of work has been tested in order to evaluate the color variation between surfaces acquired at different époques. The introduction of reliable tools of change detection in the archaeological domain is needful; in fact, the most widespread practice, among archaeologists and practitioners, is to perform a traditional monitoring of surfaces that is made of three main steps: production of a hand-made map based on a subjective analysis, selection of a sub-set of regions of interest, removal of small portion of surface for in depth analysis conducted in laboratory. To overcome this risky and time consuming process, digital automatic change detection procedure represents a turning point. To do so, automatic classification has been carried out according to two approaches: a pixel-based and an object-based method. Pixel-based classification aims to identify the classes by means of the spectral information provided by each pixel belonging to the original bands. The object-based approach operates on sets of pixels (objects/regions grouped together by means of an image segmentation technique. The methodology was tested by studying the bas-relieves of a temple located in Peru, named Huaca de la Luna. Despite the data sources were collected with unplanned surveys, the workflow proved to be a valuable solution useful to understand which are the main changes over time.

  20. Documentation and Detection of Colour Changes of Bas Relieves Using Close Range Photogrammetry

    Science.gov (United States)

    Malinverni, E. S.; Pierdicca, R.; Sturari, M.; Colosi, F.; Orazi, R.

    2017-05-01

    The digitization of complex buildings, findings or bas relieves can strongly facilitate the work of archaeologists, mainly for in depth analysis tasks. Notwithstanding, whether new visualization techniques ease the study phase, a classical naked-eye approach for determining changes or surface alteration could bring towards several drawbacks. The research work described in these pages is aimed at providing experts with a workflow for the evaluation of alterations (e.g. color decay or surface alterations), allowing a more rapid and objective monitoring of monuments. More in deep, a pipeline of work has been tested in order to evaluate the color variation between surfaces acquired at different époques. The introduction of reliable tools of change detection in the archaeological domain is needful; in fact, the most widespread practice, among archaeologists and practitioners, is to perform a traditional monitoring of surfaces that is made of three main steps: production of a hand-made map based on a subjective analysis, selection of a sub-set of regions of interest, removal of small portion of surface for in depth analysis conducted in laboratory. To overcome this risky and time consuming process, digital automatic change detection procedure represents a turning point. To do so, automatic classification has been carried out according to two approaches: a pixel-based and an object-based method. Pixel-based classification aims to identify the classes by means of the spectral information provided by each pixel belonging to the original bands. The object-based approach operates on sets of pixels (objects/regions) grouped together by means of an image segmentation technique. The methodology was tested by studying the bas-relieves of a temple located in Peru, named Huaca de la Luna. Despite the data sources were collected with unplanned surveys, the workflow proved to be a valuable solution useful to understand which are the main changes over time.

  1. European and Italian experience of Smart Cities: A model for the smart planning of city built

    Directory of Open Access Journals (Sweden)

    Starlight Vattano

    2013-05-01

    Full Text Available The construction of the city through smart measures is now a frontier reached from many cities in the world. The built environment requires smart planning able to relate urban realities that are relegated to a marginal change. But how does the smart cities can create a relationship between sustainable cities of the future and their heritage? The article highlights the way of smart urban transformation of reality European and Italian proposing critical comparisons from which to infer smart parameters most used and easy to apply for the sustainable construction of these smart cities focusing on the urban sources of intelligent retrieval for quality their historical and cultural heritage.

  2. A Smart Home Gateway Platform for Data Collection and Awareness

    OpenAIRE

    Wang, Pan; Ye, Feng; Chen, Xuejiao

    2018-01-01

    Smart homes have attracted much attention due to the expanding of Internet-of-Things (IoT) and smart devices. In this paper, we propose a smart gateway platform for data collection and awareness in smart home networks. A smart gateway will replace the traditional network gateway to connect the home network and the Internet. A smart home network supports different types of smart devices, such as in home IoT devices, smart phones, smart electric appliances, etc. A traditional network gateway is...

  3. Determining the feasibility of objective adherence measurement with blister packaging smart technology

    NARCIS (Netherlands)

    Onzenoort, H.A. van; Neef, C.; Verberk, W.W.; van Iperen, H.P.; Leeuw, P.W. de; van der Kuy, P.H.

    2012-01-01

    PURPOSE: The results of a feasibility study of blister-pack smart technology for monitoring medication adherence are reported. METHODS: Research in the area of objective therapy compliance measurement has led to the development of microprocessor-driven systems that record the time a unit dose is

  4. Correlates of Abusing and Misusing Over-the-Counter Pain Relievers Among Adult Population of Wrocław (Poland).

    Science.gov (United States)

    Wójta-Kempa, Monika; Krzyżanowski, Dominik M

    2016-01-01

    Almost 90% of households in Poland buy medicines on their own initiative. The most popular OTC medicines bought by Polish consumers are painkillers and non-steroid-anti-inflammatory drugs. The aim of this article was to recognize and describe the most important predictive factors of the abuse and misuse of over-the-counter pain relievers among adults in Wrocław (Poland). The groups of users were selected and described. Some examples of misuse were analyzed. Three hundred eighty six adult inhabitants of Wrocław took part in the survey. The quota sample was representative referring to the most important socio-demographic factors (sex and median age). Almost 91% of participants declare taking OTC pain relievers, and 1.3% of them are their daily users. Only 6.2% of adult inhabitants of Wrocław never take OTC pain relievers. The category of "heavy users" embraces 11% of participants. The most important risk factors of overusing OTC pain relievers are sex (female), age over 55 years and the low health status. Only half of participants read the box label regularly and 25% of users admit they have modified recommended doses. Over 60% shortened recommended intervals between doses and 16% took two or more different pain medications (containing different substances). The non-medical purposes of using OTC pain relievers were: tiredness (7%), stressful situations (5.4%), and discomfort (18.4%). Some users take pain medications to cure hangovers (26%), or instead of the appropriate medicine (7%). About 20% take pain medications without a doctor's advice for longer than the recommended 3 days, and 10% never consult taking such medications with doctors. Pain should be treated aggressively and successfully, especially among chronically ill patients. We should monitor the consumption of OTC pain relievers and limit their current excessively supply and high availability.

  5. Determining the feasibility of objective adherence measurement with blister packaging smart technology.

    Science.gov (United States)

    van Onzenoort, Hein A; Neef, Cees; Verberk, Willem W; van Iperen, H Peter; de Leeuw, Peter W; van der Kuy, Paul-Hugo M

    2012-05-15

    The results of a feasibility study of blister-pack smart technology for monitoring medication adherence are reported. Research in the area of objective therapy compliance measurement has led to the development of microprocessor-driven systems that record the time a unit dose is removed from blister packaging. One device under development is the Smart Blister-a label imprinted with event-detection circuitry that can be affixed to standard commercial blister cards. In the first trial of the device in actual clinical practice, 115 community-dwelling Dutch patients receiving valsartan maintenance therapy (160 mg once daily) were given 14-day blister packages equipped with the Smart Blister. On the return of empty blister cards to the 20 participating community pharmacies, the stored information was scanned and downloaded for data analysis and patient counseling purposes. A total of 245 Smart Blister-equipped packages were used by valsartan recipients during the eight-month study. The device was largely effective in recording patient and blister-card identification data and other desired information. However, in 17% of cases, the Smart Blister system registered multiple tablet-removal events at the same time, presumably indicating unintentional breakage of nearby conductive circuits and the need for design refinements. The Smart Blister-equipped medication cards were generally well received by patients and pharmacies. An evaluation of the functionality and robustness of the Smart Blister in a real-world clinical practice situation yielded some promising results, but the findings also indicated a need for design refinements and additional performance testing of the device.

  6. Energy conservation through smart homes in a smart city: A lesson for Singapore households

    International Nuclear Information System (INIS)

    Bhati, Abhishek; Hansen, Michael; Chan, Ching Man

    2017-01-01

    Energy saving is a hot topic due to the proliferation of climate changes and energy challenges globally. However, people's perception about using smart technology for energy saving is still in the concept stage. This means that people talk about environmental awareness readily, yet in reality, they accept to pay the given energy bill. Due to the availability of electricity and its integral role, modulating consumers’ attitudes towards energy savings can be a challenge. Notably, the gap in today's smart technology design in smart homes is the understanding of consumers’ behaviour and the integration of this understanding into the smart technology. As part of the Paris Climate change agreement (2015), it is paramount for Singapore to introduce smart technologies targeted to reduce energy consumption. This paper focused on the perception of Singapore households on smart technology and its usage to save energy. Areas of current research include: (1) energy consumption in Singapore households, (2) public programs and policies in energy savings, (3) use of technology in energy savings, and (4) household perception of energy savings in smart homes. Furthermore, three case studies are reviewed in relation to smart homes and smart technology, while discussing the maturity of existing solutions. - Highlights: • Analyse perception of Singapore households about the usage of smart technology to save energy. • Reviews energy consumption, public policies and household perception of energy savings. • Three case studies were developed and reviewed in relation to smart homes and smart technology. • Analyse research gap of household behaviours and perceptions as smart home design focus.

  7. Smart Energy 2012. How smart is the way towards the turnaround in the energy policy; Smart Energy 2012. Wie smart ist der Weg zur Energiewende?

    Energy Technology Data Exchange (ETDEWEB)

    Grossmann, Uwe; Kunold, Ingo (eds.)

    2012-07-01

    The contribution under consideration contains fifteen contributions of well-known authors from commercial enterprises, public institutions and universities on smart energy: (1) Smart grids, but surely (Claudia Eckert); (2) Requirements concerning the further development of data protection and data security as part of the technological change (Reinhold Harnisch); (3) Standardization in the smart grid (Harald Orlamuender); (4) IEC 61850 - The standard for energy automation (Georg Harnischmacher); (5) Smart City, the intelligent grid in the city (Michael Laskowski); (6) IKT is a basis for a real smart power distribution system (Justus Bross); (7) Power transparency and optimized building optimization by means of a holistic automation concepts (Joerg Wollert); (8) Distributed architecture for a balancing aggregation of consumption and generation of power in private households (Kilian Hemmeboehle); (9) Development of an e-energy market place and first experiences from the field test in the E-DeMa project (Bernd Werner); (10) Smart metering rollout pilot ''30,000er'' (Axel Lauterkorn); (11) Experiences with the connexion and communication to smart meters in the project eTelligence (Guenter Pistoor); (12) Smart Phoenix - Intelligent energy networks in Dortmund (Roland Brueggemann); (13) Smart planning (C. Engels); Intelligent house control by means of smart metering (Sabine Wieland); (14) Dynamic billing of energy and value-added service in the networked home (Frank C. Bormann).

  8. Deformaciones neotectónicas en el relieve fluvial de la Llanura Sur de Pinar del Río, Cuba

    OpenAIRE

    Estévez Cruz, Elmidio; Ordaz Hernández, Alexis; Hernández Santana, José Ramón

    2017-01-01

    Resumen: Las investigaciones neotectónicas se enfocan a la determinación de los movimientos tectónicos más recientes de la corteza terrestre y poseen un gran significado en el análisis geomorfológico de la estructura del relieve moderno. En las regiones relativamente llanas no siempre resulta fácil el reconocimiento de evidencias de las deformaciones neotectónicas en el relieve fluvial. Desde el punto de vista metodológico, quedó demostrada la eficiencia del empleo de los métodos geológicos, ...

  9. A smart ROV solution for ship hull and harbor inspection

    Science.gov (United States)

    Reed, Scott; Wood, Jon; Vazquez, Jose; Mignotte, Pierre-Yves; Privat, Benjamin

    2010-04-01

    Hull and harbor infrastructure inspections are frequently performed manually and involve quite a bit of risk and human and monetary resources. In any kind of threat and resource constrained environment, this involves unacceptable levels of risk and cost. Modern Remotely Operated Vehicles are highly refined machines that provide features and capabilities previously unavailable. Operations once carried out by divers can now be carried out more quickly, efficiently and safely by smart enabled ROVs. ROVs are rapidly deployable and capable of continuous, reliable operations in adverse conditions. They also provide a stable platform on which multiple sensors may be mounted and utilized to meet the harbor inspection problem. Automated Control software provides ROV's and their pilots with the capability to inspect complex, constrained environments such as those found in a harbor region. This application and the user interface allow the ROV to automatically conduct complex maneuvers relative to the area being inspected and relieves the training requirements and work load for the pilot, allowing he or she to focus on the primary task of survey, inspection and looking for possible threats (such as IEDs, Limpet Mines, signs of sabotage, etc). Real-time sensor processing tools can be integrated into the smart ROV solution to assist the operator. Automatic Target Recognition (ATR) algorithms are used to search through the sensor data collected by the ROV in real time. These algorithms provide immediate feedback on possible threats and notify the operator of regions that may require manual verification. Sensor data (sonar or video) is also mosaiced, providing the operator with real-time situational awareness and a coverage map of the hull or seafloor. Detected objects may also be placed in the context of the large scale characteristics of the hull (or bottom or pilings) and localized. Within the complex areas such as the harbor pier pilings and the running gear of the ship, real

  10. Where's the smartness of learning in smart territories ?

    Directory of Open Access Journals (Sweden)

    Carlo Giovannella

    2014-11-01

    Full Text Available In the future smarter territories are expected to induce transformations of many aspects of the learning processes, but how their smartness is and will be related to that of the learning ecosystems ? In this paper, by means of Principal Component Analysis, we critically analyse methods presently used to benchmark and produce University rankings, by focusing on the case study of the Italian Universities. The outcomes of such analysis allow us to demonstrate the existence of a strong correlation between smart cities' and universities' rankings, i.e. between learning ecosystems and their territories of reference. Present benchmarking approaches, however, need to take in more consideration people feelings and expectations. Accordingly we suggest an innovative point of view on the benchmarking of learning ecosystems based, also, on the so called flow.

  11. Smart City Through a Flexible Approach to Smart Energy

    Science.gov (United States)

    Mutule, A.; Teremranova, J.; Antoskovs, N.

    2018-02-01

    The paper provides an overview of the development trends of the smart city. Over the past decades, the trend of the new urban model called smart city has been gaining momentum, which is an aggregate of the latest technologies, intelligent administration and conscious citizens, which allows the city to actively develop, and effectively and efficiently solve the problems it is facing. Profound changes are also taking place in the energy sector. Researchers and other specialists offer a wide variety of innovative solutions and approaches for the concepts of intelligent cities. The paper reviews and analyses the existing methodological solutions in the field of power industry, as well as provides recommendations how to introduce the common platform on the basis of disparate sources of information on energy resources existing in the city as an optimal solution for developing the city's intelligence, flexibility and sustainability based on its starting conditions.

  12. Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial.

    Science.gov (United States)

    Mandel, David R; Eichas, Katy; Holmes, Judith

    2010-01-12

    Lactic acid-producing bacteria (LAB) probiotics demonstrate immunomodulating and anti-inflammatory effects and the ability to lessen the symptoms of arthritis in both animals and humans. This randomized, double-blind, placebo-controlled, parallel-design, clinical pilot trial was conducted to evaluate the effects of the LAB probiotic preparation, Bacillus coagulans GBI-30, 6086, on symptoms and measures of functional capacity in patients with rheumatoid arthritis (RA) in combination with pharmacological anti-arthritic medications. Forty-five adult men and women with symptoms of RA were randomly assigned to receive Bacillus coagulans GBI-30, 6086 or placebo once a day in a double-blind fashion for 60 days in addition to their standard anti-arthritic medications. Arthritis activity was evaluated by clinical examination, the American College of Rheumatology (ACR) criteria, the Stanford Health Assessment Questionnaire Disability Index (HAQ-DI), and laboratory tests for erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Subjects who received Bacillus coagulans GBI-30, 6086 experienced borderline statistically significant improvement in the Patient Pain Assessment score (P = .052) and statistically significant improvement in Pain Scale (P = .046) vs placebo. Compared with placebo, Bacillus coagulans GBI-30, 6086 treatment resulted in greater improvement in patient global assessment and self-assessed disability; reduction in CRP; as well as the ability to walk 2 miles, reach, and participate in daily activities. There were no treatment-related adverse events reported throughout this study. Results of this pilot study suggest that adjunctive treatment with Bacillus coagulans GBI-30, 6086 LAB probiotic appeared to be a safe and effective for patients suffering from RA. Because of the low study population size, larger trials are needed to verify these results. ACTRN12609000435280.

  13. Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial

    Directory of Open Access Journals (Sweden)

    Eichas Katy

    2010-01-01

    Full Text Available Abstract Background Lactic acid-producing bacteria (LAB probiotics demonstrate immunomodulating and anti-inflammatory effects and the ability to lessen the symptoms of arthritis in both animals and humans. This randomized, double-blind, placebo-controlled, parallel-design, clinical pilot trial was conducted to evaluate the effects of the LAB probiotic preparation, Bacillus coagulans GBI-30, 6086, on symptoms and measures of functional capacity in patients with rheumatoid arthritis (RA in combination with pharmacological anti-arthritic medications. Methods Forty-five adult men and women with symptoms of RA were randomly assigned to receive Bacillus coagulans GBI-30, 6086 or placebo once a day in a double-blind fashion for 60 days in addition to their standard anti-arthritic medications. Arthritis activity was evaluated by clinical examination, the American College of Rheumatology (ACR criteria, the Stanford Health Assessment Questionnaire Disability Index (HAQ-DI, and laboratory tests for erythrocyte sedimentation rate (ESR and C-reactive protein (CRP. Results Subjects who received Bacillus coagulans GBI-30, 6086 experienced borderline statistically significant improvement in the Patient Pain Assessment score (P = .052 and statistically significant improvement in Pain Scale (P = .046 vs placebo. Compared with placebo, Bacillus coagulans GBI-30, 6086 treatment resulted in greater improvement in patient global assessment and self-assessed disability; reduction in CRP; as well as the ability to walk 2 miles, reach, and participate in daily activities. There were no treatment-related adverse events reported throughout this study. Conclusions Results of this pilot study suggest that adjunctive treatment with Bacillus coagulans GBI-30, 6086 LAB probiotic appeared to be a safe and effective for patients suffering from RA. Because of the low study population size, larger trials are needed to verify these results. Trial registration ACTRN12609000435280

  14. Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial

    Science.gov (United States)

    2010-01-01

    Background Lactic acid-producing bacteria (LAB) probiotics demonstrate immunomodulating and anti-inflammatory effects and the ability to lessen the symptoms of arthritis in both animals and humans. This randomized, double-blind, placebo-controlled, parallel-design, clinical pilot trial was conducted to evaluate the effects of the LAB probiotic preparation, Bacillus coagulans GBI-30, 6086, on symptoms and measures of functional capacity in patients with rheumatoid arthritis (RA) in combination with pharmacological anti-arthritic medications. Methods Forty-five adult men and women with symptoms of RA were randomly assigned to receive Bacillus coagulans GBI-30, 6086 or placebo once a day in a double-blind fashion for 60 days in addition to their standard anti-arthritic medications. Arthritis activity was evaluated by clinical examination, the American College of Rheumatology (ACR) criteria, the Stanford Health Assessment Questionnaire Disability Index (HAQ-DI), and laboratory tests for erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Results Subjects who received Bacillus coagulans GBI-30, 6086 experienced borderline statistically significant improvement in the Patient Pain Assessment score (P = .052) and statistically significant improvement in Pain Scale (P = .046) vs placebo. Compared with placebo, Bacillus coagulans GBI-30, 6086 treatment resulted in greater improvement in patient global assessment and self-assessed disability; reduction in CRP; as well as the ability to walk 2 miles, reach, and participate in daily activities. There were no treatment-related adverse events reported throughout this study. Conclusions Results of this pilot study suggest that adjunctive treatment with Bacillus coagulans GBI-30, 6086 LAB probiotic appeared to be a safe and effective for patients suffering from RA. Because of the low study population size, larger trials are needed to verify these results. Trial registration ACTRN12609000435280 PMID:20067641

  15. Fall Detection Using Commodity Smart Watch and Smart Phone

    OpenAIRE

    Maglogiannis , Ilias; Ioannou , Charalampos; Spyroglou , George; Tsanakas , Panayiotis

    2014-01-01

    Part 3: Social Media and Mobile Applications of AI; International audience; Human motion data captured from wearable devices such as smart watches can be utilized for activity recognition or emergency event detection, especially in the case of elderly or disabled people living independently in their homes. The output of such sensors is data streams that require real-time recognition, especially in emergency situations. This paper presents a novel application that utilizes the low-cost Pebble ...

  16. SMART-ITEM: IoT-Enabled Smart Living

    OpenAIRE

    Kor, A; Pattinson, C; Yanovsky, M; Kharchenko, V

    2017-01-01

    The main goal of this proposed project is to harness the emerging IoT technology to empower elderly population to self-manage their own health, stay active, healthy, and independent as long as possible within a smart and secured living environment. An integrated open-sourced IoT ecosystem will be developed. It will encompass the entire data lifecycle which involves the following processes: data acquisition, data transportation; data integration, processing, manipulation and computation; visua...

  17. Smart grid for comfort; Smart grid voor comfort

    Energy Technology Data Exchange (ETDEWEB)

    Zeiler, W.; Van der Velden, J.A.J. [Kropman, Rijswijk (Netherlands); Vissers, D.R.; Maaijen, H.N. [Faculteit Bouwkunde, Technische Universiteit Eindhoven TUE, Eindhoven (Netherlands); Kling, W.L. [Faculteit Electrical Engineering, Technische Universiteit Eindhoven TUE, Eindhoven (Netherlands); Larsen, J.P. [Sense Observation Systems, Rotterdam (Netherlands)

    2012-04-15

    A new control strategy was developed based on the application of wireless sensor network with the connection to a smart grid to investigate if it is possible to save energy on the level of the user under the condition of maintaining the same or even improved level of individual comfort. By using different scenarios, for individual comfort and energy consumption, agents provide the steering of the process control This forms the basis of a new approach to optimize the energy consumption, after which the effect of it can be used on the level of residential building to optimize the interaction with the electrical infrastructure, the smart grid. [Dutch] Er vindt onderzoek plaats naar een nieuwe regelstrategie gebaseerd op de toepassing van een draadloos sensor netwerk dat is gekoppeld aan het smart grid. Doel van deze regelstrategie is om op gebruikersniveau energie te kunnen besparen met behoud of zelfs verbetering van het individueel comfort. Er zijn verschillende scenario's voor individueel comfort en energiegebruik van apparatuur met behulp van agents die voor de aansturing kunnen zorgen. Zo wordt de kern van de energievraag geoptimaliseerd. De doorwerking hiervan tot op het niveau van woninggebouw en de koppeling met het externe elektriciteitsnet kan vervolgens worden geoptimaliseerd.

  18. Design of smart functional apparel products for moxa moxibustion

    Science.gov (United States)

    Li, Li; Au, Wai-man; Ding, Feng; Wong, Kwok-shing

    2013-08-01

    Moxa Moxibustion is a common traditional Chinese therapy in which burning Moxa is applied to affected body areas. This method has been employed for thousands of years to achieve certain medical objectives, such as pain relief or antibacterial and anti-inflammatory effects. Its therapeutic effectiveness has been demonstrated successfully both in research and clinical studies. However, this traditional approach may cause undesirable side effects, for example: 1) burning of Moxa produces by-products such as smoke and ash; 2) patients are at risk of being burnt; 3) the active ingredients of the Moxa leaf oil are volatile, odorous, unstable in air and easy to dissipate, and difficult to store and transport; 4) it is inconvenient to operate. These side effects limit its further high-potential and high-value applications. This study is aimed at developing a multi-functional smart textile system that will adopt smart fabrics containing encapsulated Moxa oil integrated with thermally conductive materials to replace the conventional Moxa products. This will efficiently deliver the active ingredients of Moxa to a human body at optimum conditions, i.e., in a precise and controllable way, with maximum convenience and a high level of comfort. Doing so would solve the existing problems mentioned above. Both garment design skill and textile technology will be applied to Moxa Moxibustion textile to enhance the aesthetics and functionality. The smart garment performance will be assessed subjectively in a clinical trial and objectively by a number of instrumental methods.

  19. Traffic Information Systems for Smart Mobility as part of Smart Cities

    OpenAIRE

    Suske, David; Touko Tcheumadjeu, Louis Calvin; Sohr, Alexander; Xiaoxu, Bei

    2016-01-01

    The unlimited and unrestricted mobility of people and goods in urban areas is one of the key factors for economic and social development of the city. Today with the availability of smart technologies and various intelligent transportation and telematics solutions the Smart Mobility as part of a Smart City is possible to maintain the mobility ecosystem in the city. But to make the urban mobility smart by assuring the sustainability, safety, low emission and comfort in urban transport new mobil...

  20. Smart Home Test Bed: Examining How Smart Homes Interact with the Power Grid

    Energy Technology Data Exchange (ETDEWEB)

    2016-11-01

    This fact sheet highlights the Smart Home Test Bed capability at the Energy Systems Integration Facility. The National Renewable Energy Laboratory (NREL) is working on one of the new frontiers of smart home research: finding ways for smart home technologies and systems to enhance grid operations in the presence of distributed, clean energy technologies such as photovoltaics (PV). To help advance this research, NREL has developed a controllable, flexible, and fully integrated Smart Home Test Bed.

  1. 2016 SmartWay Affiliate Challenge Recognition Webinar

    Science.gov (United States)

    This EPA presentation gives an overview of the SmartWay program and showcases the SmartWay Affiliate awardees raising awareness of the benefits of the SmartWay program and sustainable freight transportation.

  2. Smart Cards 101: Everything a Beginner Needs To Get Started.

    Science.gov (United States)

    Wiens, Janet

    2001-01-01

    Discusses how to implement a smart card system at a college or university, and explains what smart cards are, their potential applications, benefits, and costs. Provides a resource for obtaining additional information about smart cards. (GR)

  3. Comprehensive measures of sound exposures in cinemas using smart phones.

    Science.gov (United States)

    Huth, Markus E; Popelka, Gerald R; Blevins, Nikolas H

    2014-01-01

    Sensorineural hearing loss from sound overexposure has a considerable prevalence. Identification of sound hazards is crucial, as prevention, due to a lack of definitive therapies, is the sole alternative to hearing aids. One subjectively loud, yet little studied, potential sound hazard is movie theaters. This study uses smart phones to evaluate their applicability as a widely available, validated sound pressure level (SPL) meter. Therefore, this study measures sound levels in movie theaters to determine whether sound levels exceed safe occupational noise exposure limits and whether sound levels in movie theaters differ as a function of movie, movie theater, presentation time, and seat location within the theater. Six smart phones with an SPL meter software application were calibrated with a precision SPL meter and validated as an SPL meter. Additionally, three different smart phone generations were measured in comparison to an integrating SPL meter. Two different movies, an action movie and a children's movie, were measured six times each in 10 different venues (n = 117). To maximize representativeness, movies were selected focusing on large release productions with probable high attendance. Movie theaters were selected in the San Francisco, CA, area based on whether they screened both chosen movies and to represent the largest variety of theater proprietors. Measurements were analyzed in regard to differences between theaters, location within the theater, movie, as well as presentation time and day as indirect indicator of film attendance. The smart phone measurements demonstrated high accuracy and reliability. Overall, sound levels in movie theaters do not exceed safe exposure limits by occupational standards. Sound levels vary significantly across theaters and demonstrated statistically significant higher sound levels and exposures in the action movie compared to the children's movie. Sound levels decrease with distance from the screen. However, no influence on

  4. Bandwidth Analysis of Smart Meter Network Infrastructure

    DEFF Research Database (Denmark)

    Balachandran, Kardi; Olsen, Rasmus Løvenstein; Pedersen, Jens Myrup

    2014-01-01

    Advanced Metering Infrastructure (AMI) is a net-work infrastructure in Smart Grid, which links the electricity customers to the utility company. This network enables smart services by making it possible for the utility company to get an overview of their customers power consumption and also control...... devices in their costumers household e.g. heat pumps. With these smart services, utility companies can do load balancing on the grid by shifting load using resources the customers have. The problem investigated in this paper is what bandwidth require-ments can be expected when implementing such network...... to utilize smart meters and which existing broadband network technologies can facilitate this smart meter service. Initially, scenarios for smart meter infrastructure are identified. The paper defines abstraction models which cover the AMI scenarios. When the scenario has been identified a general overview...

  5. Smart city planning and development shortcomings

    Directory of Open Access Journals (Sweden)

    Margarita Angelidou

    2017-04-01

    Full Text Available This paper explores smart city planning and development shortcomings. In particular, it investigates eleven cases of smart city strategies and the shortcomings that were observed during their planning and implementation stages. The cases include: Barcelona Smart City, PlanlT Valley, Stockholm Smart City, Cyberjaya, King Abdullah Economic City, Masdar City, Skolkovo, Songdo International Business District, Chicago Smart City, Rio de Janeiro Smart City, and Konza Technology City. The paper proceeds with the synthesis of the findings and their critical appraisal. Shortcomings are classified into economic and budget shortages, bureaucratic and organizational challenges, challenges in the development and layout of digital services, poor physical planning, struggle to attract investment and support the development of new businesses, low performance in attracting and engaging users, and stakeholder resistance. In turn, the shortcomings are clustered in two distinct groups and analyzed in terms of causes and effects. The paper closes with mitigation propositions, accounting for past experience and novel approaches to this end.

  6. Triple-layer smart grid business model

    DEFF Research Database (Denmark)

    Ma, Zheng; Lundgaard, Morten; Jørgensen, Bo Nørregaard

    2016-01-01

    Viewing the smart grid with the theory of business models may open opportunities in understanding and capturing values in new markets. This study tries to discover and map the smart grid ecosystem-based business model framework with two different environments (sub-Saharan Africa and Denmark......), and identifies the parameters for the smart grid solutions to the emerging markets. This study develops a triple-layer business model including the organizational (Niche), environmental (Intermediate), and global (Dominators) factors. The result uncovers an interface of market factors and stakeholders...... in a generic smart grid constellation. The findings contribute the transferability potential of the smart grid solutions between countries, and indicate the potential to export and import smart grid solutions based on the business modeling....

  7. Basis of valve operator selection for SMART

    International Nuclear Information System (INIS)

    Kang, H. S.; Lee, D. J.; See, J. K.; Park, C. K.; Choi, B. S.

    2000-05-01

    SMART, an integral reactor with enhanced safety and operability, is under development for use of the nuclear energy. The valve operator of SMART system were selected through the data survey and technical review of potential valve fabrication vendors, and it will provide the establishment and optimization of the basic system design of SMART. In order to establish and optimize the basic system design of SMART, the basis of selection for the valve operator type were provided based on the basic design requirements. The basis of valve operator selection for SMART will be used as a basic technical data for the SMART basic and detail design and a fundamental material for the new reactor development in the future

  8. A DISTRIBUTED SMART HOME ARTIFICIAL INTELLIGENCE SYSTEM

    DEFF Research Database (Denmark)

    Lynggaard, Per

    2013-01-01

    A majority of the research performed today explore artificial intelligence in smart homes by using a centralized approach where a smart home server performs the necessary calculations. This approach has some disadvantages that can be overcome by shifting focus to a distributed approach where...... the artificial intelligence system is implemented as distributed as agents running parts of the artificial intelligence system. This paper presents a distributed smart home architecture that distributes artificial intelligence in smart homes and discusses the pros and cons of such a concept. The presented...... distributed model is a layered model. Each layer offers a different complexity level of the embedded distributed artificial intelligence. At the lowest layer smart objects exists, they are small cheap embedded microcontroller based smart devices that are powered by batteries. The next layer contains a more...

  9. Minat Masyarakat dalam Menggunakan Smart Appliances

    Directory of Open Access Journals (Sweden)

    Diah Yuniarti

    2014-09-01

    Full Text Available Harga sumber energi yang semakin naik dari tahun ke tahun dan kemajuan teknologi telah mendorong perkembangan smart grid. Smart appliance merupakan salah satu komponen penting dalam smart grid. Penerapan smart appliance sejalan dengan kebijakan untuk mengurangi konsumsi energi, mengurangi emisi karbon dan penyediaan energi dari energi terbarukan. Penetrasi telepon bergerak turut memudahkan manajemen energi dan otomatisasi home appliance. Penelitian ini dilakukan untuk menganalisis minat masyarakat, yang merupakan aktor aktif dalam konsumsi dan manajemen energi di rumah tangga. Data penelitian dianalisis  dengan menggunakan metode structural equation modeling (SEM Hasil penelitian menunjukkan bahwa variabel enjoyment memiliki pengaruh yang signifikan terhadap minat dalam menggunakan smart appliance. Sedangkan, variabel compatibility ease of use, relative advantage dan image tidak memiliki pengaruh yang signifikan terhadap minat menggunakan smart appliance.

  10. Basis of valve operator selection for SMART

    Energy Technology Data Exchange (ETDEWEB)

    Kang, H. S.; Lee, D. J.; See, J. K.; Park, C. K.; Choi, B. S

    2000-05-01

    SMART, an integral reactor with enhanced safety and operability, is under development for use of the nuclear energy. The valve operator of SMART system were selected through the data survey and technical review of potential valve fabrication vendors, and it will provide the establishment and optimization of the basic system design of SMART. In order to establish and optimize the basic system design of SMART, the basis of selection for the valve operator type were provided based on the basic design requirements. The basis of valve operator selection for SMART will be used as a basic technical data for the SMART basic and detail design and a fundamental material for the new reactor development in the future.

  11. Japan. Superconductivity for Smart Grids

    Energy Technology Data Exchange (ETDEWEB)

    Hayakawa, K.

    2012-11-15

    Currently, many smart grid projects are running or planned worldwide. These aim at controlling the electricity supply more efficiently and more stably in a new power network system. In Japan, especially superconductivity technology development projects are carried out to contribute to the future smart grid. Japanese cable makers such as Sumitomo Electric and Furukawa Electric are leading in the production of high-temperature superconducting (HTS) power cables. The world's largest electric current and highest voltage superconductivity proving tests have been started this year. Big cities such as Tokyo will be expected to introduce the HTS power cables to reduce transport losses and to meet the increased electricity demand in the near future. Superconducting devices, HTS power cables, Superconducting Magnetic Energy Storage (SMES) and flywheels are the focus of new developments in cooperations between companies, universities and research institutes, funded by the Japanese research and development funding organization New Energy and Industrial Technology Development Organization (NEDO)

  12. Smart Metering System for Microgrids

    DEFF Research Database (Denmark)

    Palacios-Garcia, Emilio; Guan, Yajuan; Savaghebi, Mehdi

    2015-01-01

    suppliers, but they can also play a big role in the control of the Microgrid since the recorded power and energy profiles can be integrated in energy management systems (EMS). In addition, basic power quality (PQ) disturbance can de detected and reported by some advanced metering systems. Thus, this paper...... will expose an example of Smart Meters integration in a Microgrid scenario, which is the Intelligent Microgrid Lab of Aalborg University (AAU). To do this, first the installation available in the Microgrid Lab will be introduced. Then, three different test scenarios and their respective results...... will be presented, regarding the capabilities of this system and the advantages of integration the Smart Meters information in the Microgrid control....

  13. Hierarchical Control for Smart Grids

    DEFF Research Database (Denmark)

    Trangbæk, K; Bendtsen, Jan Dimon; Stoustrup, Jakob

    2011-01-01

    of autonomous consumers. The control system is tasked with balancing electric power production and consumption within the smart grid, and makes active use of the flexibility of a large number of power producing and/or power consuming units. The objective is to accommodate the load variation on the grid, arising......This paper deals with hierarchical model predictive control (MPC) of smart grid systems. The design consists of a high level MPC controller, a second level of so-called aggregators, which reduces the computational and communication-related load on the high-level control, and a lower level...... on one hand from varying consumption, and on the other hand by natural variations in power production e.g. from wind turbines. The high-level MPC problem is solved using quadratic optimisation, while the aggregator level can either involve quadratic optimisation or simple sorting-based min-max solutions...

  14. SMART core protection system design

    International Nuclear Information System (INIS)

    Lee, J. K.; Park, H. Y.; Koo, I. S.; Park, H. S.; Kim, J. S.; Son, C. H.

    2003-01-01

    SMART COre Protection System(SCOPS) is designed with real-tims Digital Signal Processor(DSP) board and Network Interface Card(NIC) board. SCOPS has a Control Rod POSition (CRPOS) software module while Core Protection Calculator System(CPCS) consists of Core Protection Calculators(CPCs) and Control Element Assembly(CEA) Calculators(CEACs) in the commercial nuclear plant. It's not necessary to have a independent cabinets for SCOPS because SCOPS is physically very small. Then SCOPS is designed to share the cabinets with Plant Protection System(PPS) of SMART. Therefor it's very easy to maintain the system because CRPOS module is used instead of the computer with operating system

  15. [Smart cards in health services].

    Science.gov (United States)

    Rienhoff, O

    2001-10-01

    Since the early 1980-ties it has been tried to utilise smart cards in health care. All industrialised countries participated in those efforts. The most sustainable analyses took place in Europe--specifically in the United Kingdom, France, and Germany. The first systems installed (the service access cards in F and G, the Health Professional Card in F) are already conceptionally outdated today. The senior understanding of the great importance of smart cards for security of electronic communication in health care does contrast to a hesitating behaviour of the key players in health care and health politics in Germany. There are clear hints that this may relate to the low informatics knowledge of current senior management.

  16. Smart antennas for nuclear instruments

    International Nuclear Information System (INIS)

    Jain, Ranjan Bala; Singhi, B.M.

    2005-01-01

    The advances in the field of computer and communications are leading to the development of smart embedded nuclear instruments. These instruments have highly sophisticated signal-processing algorithms based on FPGA and ASICS, provisions of present day connectivity and user interfaces. The developments in the connectivity, standards and bus technologies have made possible to access these instruments on LAN and WAN with suitable reliability and security. To get rid of wires i.e. in order to access these instruments, without wires at any place, wireless technology has evolved and become integral part of day-to-day activities. The environment monitoring can be done remotely, if smart antennas are incorporated on these instruments

  17. Reliability evaluation of smart distribution grids

    OpenAIRE

    Kazemi, Shahram

    2011-01-01

    The term "Smart Grid" generally refers to a power grid equipped with the advanced technologies dedicated for purposes such as reliability improvement, ease of control and management, integrating of distributed energy resources and electricity market operations. Improving the reliability of electric power delivered to the end users is one of the main targets of employing smart grid technologies. The smart grid investments targeted for reliability improvement can be directed toward the generati...

  18. PLCs used in smart home control

    Science.gov (United States)

    Barz, C.; Deaconu, S. I.; Latinovic, T.; Berdie, A.; Pop-Vadean, A.; Horgos, M.

    2016-02-01

    This paper presents the realization of a smart home automation using Siemens PLCs. The smart home interface is realized using the HMI Weintek eMT3070a touchscreen, which shows the window for controlling and monitoring the lighting, room temperature, irrigation systems, swimming pool, etc. By using PLCs, the smart home can be controlled via Ethernet and it can be programmed to the needs of tenants.

  19. Development of a Smart Grid Simulation Environment

    OpenAIRE

    Delamare, J; Bitachon, B.; Peng, Z.; Wang, Y.; Haverkort, Boudewijn R.H.M.; Jongerden, M.R.

    2015-01-01

    With the increased integration of renewable energy sources the interaction between energy producers and consumers has become a bi-directional exchange. Therefore, the electrical grid must be adapted into a smart grid which effectively regulates this two-way interaction. With the aid of simulation, stakeholders can obtain information on how to properly develop and control the smart grid. In this paper, we present the development of an integrated smart grid simulation model, using the Anylogic ...

  20. Smart Grid Status and Metrics Report

    Energy Technology Data Exchange (ETDEWEB)

    Balducci, Patrick J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Weimar, Mark R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kirkham, Harold [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-07-01

    To convey progress made in achieving the vision of a smart grid, this report uses a set of six characteristics derived from the National Energy Technology Laboratory Modern Grid Strategy. It measures 21 metrics to provide insight into the grid’s capacity to embody these characteristics. This report looks across a spectrum of smart grid concerns to measure the status of smart grid deployment and impacts.

  1. SMART - Structure mechanical analysis in reactor technology

    International Nuclear Information System (INIS)

    Argyris, J.H.; Faust, G.; Szimmat, J.; Warnke, E.P.; Willam, K.J.

    1975-01-01

    The programme system SMART was developed in the years 1970-75 to calculate prestressed-concrete reactor pressure vessels with finite elements. The present report outlines the course and present state of research and development work. Following the specification of SMART, a brief presentation of the analytical possibilities and of the expansions for investigating creep, ultimate load behaviour and thermodiffusion is given. In conclusion, the fields of application of SMART are illustrated by means of examples. (orig./LH) [de

  2. Smart TV Privacy Risks and Protection Measures

    OpenAIRE

    Ghiglieri, Marco

    2017-01-01

    Smart TVs have been becoming more popular in recent years. They are not entirely new devices, they are rather traditional TVs with current technology and increased functionality. In addition to streaming traditional broadcast content, Smart TVs facilitate access to Internet content and services. Thus, different Internet functionality on Smart TVs is available. For instance, Facebook, different video on demand services or online games. Some Internet functionality can access and uti...

  3. Securing the smart grid information exchange

    Energy Technology Data Exchange (ETDEWEB)

    Fries, Steffen; Falk, Rainer [Siemens AG, Corporate Technology, Muenchen (Germany)

    2012-07-01

    The smart grid is based on information exchange between various stakeholders using open communication technologies, to control the physical electric grid through the information grid. Protection against cyber attacks is essential to ensure a reliable operation of the smart grid. This challenge is addressed by various regulatory, standardization, and research activities. After giving an overview of the security demand of a smart grid, existing and appearing standardization activities are described. (orig.)

  4. Smart TV privacy risks and protection measures

    OpenAIRE

    Ghiglieri, Marco

    2017-01-01

    Smart TVs have been becoming more popular in recent years. They are not entirely new devices, they are rather traditional TVs with current technology and increased functionality. In addition to streaming traditional broadcast content, Smart TVs facilitate access to Internet content and services. Thus, different Internet functionality on Smart TVs is available. For instance, Facebook, different video on demand services or online games. Some Internet functionality can access and uti...

  5. Complex IoT Systems as Enablers for Smart Homes in a Smart City Vision.

    Science.gov (United States)

    Lynggaard, Per; Skouby, Knud Erik

    2016-11-02

    The world is entering a new era, where Internet-of-Things (IoT), smart homes, and smart cities will play an important role in meeting the so-called big challenges. In the near future, it is foreseen that the majority of the world's population will live their lives in smart homes and in smart cities. To deal with these challenges, to support a sustainable urban development, and to improve the quality of life for citizens, a multi-disciplinary approach is needed. It seems evident, however, that a new, advanced Information and Communications Technology ICT infrastructure is a key feature to realize the "smart" vision. This paper proposes a specific solution in the form of a hierarchical layered ICT based infrastructure that handles ICT issues related to the "big challenges" and seamlessly integrates IoT, smart homes, and smart city structures into one coherent unit. To exemplify benefits of this infrastructure, a complex IoT system has been deployed, simulated and elaborated. This simulation deals with wastewater energy harvesting from smart buildings located in a smart city context. From the simulations, it has been found that the proposed infrastructure is able to harvest between 50% and 75% of the wastewater energy in a smart residential building. By letting the smart city infrastructure coordinate and control the harvest time and duration, it is possible to achieve considerable energy savings in the smart homes, and it is possible to reduce the peak-load for district heating plants.

  6. A Brief Survey on the Advancement of Smart Grid

    OpenAIRE

    Chandra Mukherjee,; Pratibha Bharti

    2014-01-01

    The Smart Grid, regarded as the next generation power grid, uses two-way communication of electricity and information to create a widely distributed automated energy delivery network. In this article, a review work on different aspects on the enabling technologies for the Smart Grid is being presented. Infrastructure of Smart Grid can be broadly classified into three terms namely the smart infrastructure system, the smart management system, and the smart protection system. We ...

  7. Healthcare Applications of Smart Watches

    Science.gov (United States)

    Lu, Tsung-Chien; Fu, Chia-Ming; Ma, Matthew Huei-Ming; Fang, Cheng-Chung

    2016-01-01

    Summary Objective The aim of this systematic review is to synthesize research studies involving the use of smart watch devices for healthcare. Materials and Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was chosen as the systematic review methodology. We searched PubMed, CINAHL Plus, EMBASE, ACM, and IEEE Xplore. In order to include ongoing clinical trials, we also searched ClinicalTrials.gov. Two investigators evaluated the retrieved articles for inclusion. Discrepancies between investigators regarding article inclusion and extracted data were resolved through team discussion. Results 356 articles were screened and 24 were selected for review. The most common publication venue was in conference proceedings (13, 54%). The majority of studies were published or presented in 2015 (19, 79%). We identified two registered clinical trials underway. A large proportion of the identified studies focused on applications involving health monitoring for the elderly (6, 25%). Five studies focused on patients with Parkinson’s disease and one on cardiac arrest. There were no studies which reported use of usability testing before implementation. Discussion Most of the reviewed studies focused on the chronically ill elderly. There was a lack of detailed description of user-centered design or usability testing before implementation. Based on our review, the most commonly used platform in healthcare research was that of the Android Wear. The clinical application of smart watches as assistive devices deserves further attention. Conclusion Smart watches are unobtrusive and easy to wear. While smart watch technology supplied with biosensors has potential to be useful in a variety of healthcare applications, rigorous research with their use in clinical settings is needed. PMID:27623763

  8. SMART SECURITY SYSTEM FOR CARS

    OpenAIRE

    Akshay V. Balki*, Ankit A. Ramteke, Akshay Dhankar, Prof. Nilesh S. Panchbudhe

    2017-01-01

    This propose work is an attempt to model design an smart advance vehicle security system that uses biometric scanner and RFID card reader to give ignition pulse using two main module and to prevent theft. The system contains biometric scanner, RFID card reader, alcohol sensor, vibration sensor, GSM module, microcontroller (8051), relay switch, high voltage mesh..The safety of car is exceptionally essential. It provides pulse to ignition system by synchronizing driver’s data from license and t...

  9. Metrics for smart security awareness

    CSIR Research Space (South Africa)

    Labuschagne, William A

    2017-06-01

    Full Text Available informing the response teams for reparations. These capabilities are possible by collecting data from the environment and ensuring intelligence is developed to react automatically without human intervention. The concept of smart cities has also been.... The data would be transported to a centralized situational awareness capability for analyses and create the appropriate response in the form of remedial action. The use of threat intelligence feeds could automatically sense the existence of a new threat...

  10. Inkjet printed wireless smart bandage

    KAUST Repository

    Farooqui, Muhammad Fahad; Shamim, Atif

    2016-01-01

    Chronic wounds affect millions of patients around the world and requires a major portion of health care budget for treatment. In this article, we present an unprecedented low cost continuous wireless monitoring system, realized through inkjet printing on a standard bandage strip, which can send early warnings as well as record long term wound progression data. The smart bandage can communicate upto a distance of 60 m when worn on the body.

  11. Micro Grid: A Smart Technology

    OpenAIRE

    Naveenkumar, M; Ratnakar, N

    2012-01-01

    Distributed Generation (DG) is an approach that employs small-scale technologies to produce electricity close to the end users of power. Todays DG technologies often consist of renewable generators, and offer a number of potential benefits. This paper presents a design of micro grid as part of Smart grid technologies with renewable energy resources like solar, wind and Diesel generator. The design of the microgrid with integration of Renewable energy sources are done in PSCAD/EMTDC.This paper...

  12. Privacy concerns in smart cities

    OpenAIRE

    van Zoonen, Liesbet

    2016-01-01

    textabstractIn this paper a framework is constructed to hypothesize if and how smart city technologies and urban big data produce privacy concerns among the people in these cities (as inhabitants, workers, visitors, and otherwise). The framework is built on the basis of two recurring dimensions in research about people's concerns about privacy: one dimensions represents that people perceive particular data as more personal and sensitive than others, the other dimension represents that people'...

  13. Inkjet printed wireless smart bandage

    KAUST Repository

    Farooqui, Muhammad Fahad

    2016-12-19

    Chronic wounds affect millions of patients around the world and requires a major portion of health care budget for treatment. In this article, we present an unprecedented low cost continuous wireless monitoring system, realized through inkjet printing on a standard bandage strip, which can send early warnings as well as record long term wound progression data. The smart bandage can communicate upto a distance of 60 m when worn on the body.

  14. Use of symptom-relieving drugs before and after surgery for urinary incontinence in women: a cohort study

    DEFF Research Database (Denmark)

    Sørensen, Guldberg; Brostrøm, Søren; Kesmodel, Ulrik Schiøler

    2013-01-01

    To describe the use of symptom-relieving drugs (antimuscarinic drugs or duloxetine) before and after surgery for urinary incontinence (UI); and for those with use of antimuscarinic drugs or duloxetine before surgery, to estimate the risk of being a postoperative user, relative to those without use...

  15. Canadian Economic Evaluation of Budesonide-Formoterol as Maintenance and Reliever Treatment in Patients with Moderate to Severe Asthma

    Directory of Open Access Journals (Sweden)

    Elizabeth Miller

    2007-01-01

    Full Text Available OBJECTIVES: To compare the cost-effectiveness of budesonide-formoterol in a single inhaler used as both maintenance and reliever medication versus clinician-directed titration of salmeterol-fluticasone as maintenance medication, plus salbutamol taken as needed, in controlling asthma in adults and adolescents.

  16. Implementing the PAIN RelieveIt Randomized Controlled Trial in Hospice Care: Mechanisms for Success and Meeting PCORI Methodology Standards.

    Science.gov (United States)

    Ezenwa, Miriam O; Suarez, Marie L; Carrasco, Jesus D; Hipp, Theresa; Gill, Anayza; Miller, Jacob; Shea, Robert; Shuey, David; Zhao, Zhongsheng; Angulo, Veronica; McCurry, Timothy; Martin, Joanna; Yao, Yingwei; Molokie, Robert E; Wang, Zaijie Jim; Wilkie, Diana J

    2017-07-01

    This purpose of this article is to describe how we adhere to the Patient-Centered Outcomes Research Institute's (PCORI) methodology standards relevant to the design and implementation of our PCORI-funded study, the PAIN RelieveIt Trial. We present details of the PAIN RelieveIt Trial organized by the PCORI methodology standards and components that are relevant to our study. The PAIN RelieveIt Trial adheres to four PCORI standards and 21 subsumed components. The four standards include standards for formulating research questions, standards associated with patient centeredness, standards for data integrity and rigorous analyses, and standards for preventing and handling missing data. In the past 24 months, we screened 2,837 cancer patients and their caregivers; 874 dyads were eligible; 223.5 dyads consented and provided baseline data. Only 55 patients were lost to follow-up-a 25% attrition rate. The design and implementation of the PAIN RelieveIt Trial adhered to PCORI's methodology standards for research rigor.

  17. Stress relieving procedure and facility by shot-peening the inside surface of NPP steam generators tubes

    International Nuclear Information System (INIS)

    Banica, I.; Maioru, H.

    1994-01-01

    Residual stress relieving of the transition zones between the deformed part and the non deformed part of the heat exchanger tubes expanded in tube sheets of the NPP equipment, is a technological problem attacked on international level as well as on national level through the continuing programme initiated by ICEMENERG. The most recent statistical data point out that over 75% of tube failures are taking place in the tube-to-tubesheet connection zone, a great number of them being produced in this area by intergranular attack and stress corrosion cracking. The increased occurrence of these incidents is explained first by the existence of residual stresses inside tube surfaces, induced by expanding the tubes. Relieving these residual stresses is the purpose of the outlined procedure and it is achieved by overlapping effects (compression stresses added over tensile stresses). In this paper aspects of the procedure are presented and also a facility is described for stress relieving by introducing compressive stresses from uniform and generalized collisions of the inside surface with micro balls of great kinetic energy carried by a pressurized gas. The stress relieving facility can be acted by remote control, the whole process being completely automatic. The procedure aims to the operation maintenance of the NPP steam generators. (Author)

  18. Kinetic mechanism of an aldehyde reductase of Saccharomyces cerevisiae that relieves toxicity of furfural and 5-hydroxymethylfurfural

    Science.gov (United States)

    An effective means of relieving the toxicity of furan aldehydes, furfural (FFA) and 5-hydroxymethylfurfural (HMF), on fermenting organisms is essential for achieving efficient fermentation of lignocellulosic biomass to ethanol and other products. Ari1p, an aldehyde reductase from Saccharomyces cerev...

  19. Smart City Environmental Pollution Prevention and Control Design Based on Internet of Things

    Science.gov (United States)

    Peng, He; Bohong, Zheng; Qinpei, Kuang

    2017-11-01

    Due to increasingly serious urban pollution, this paper proposes an environmental pollution prevention and control system in combination with Internet of things. The system transfers data through the Internet, which also utilizes sensor, pH sensor and smoke sensor to obtain environmental data. Besides, combined with the video data acquired through monitoring, the data are transferred to data center to analyze the haze pollution, water pollution and fire disaster in environment. According to the results, multi-purpose vehicles are mobilized to complete the tasks such as spraying water to relieve haze, water source purification and fire fighting in city environment. Experiments show that the environmental pollution prevention and control system designed in this paper can automatically complete the urban environmental pollution detection, prevention and control, which thus reduces human and material resources and improves the efficiency of pollution prevention and control. Therefore, it possesses greatly practical significance to the construction of smart city.

  20. A Development Framework for Smart Cities Assessment

    Directory of Open Access Journals (Sweden)

    Mustafa Khudhair Al-Alwani

    2018-02-01

    Full Text Available A smart city is rising as an approach and strategy to reduce the troubles produced by rapid urbanization and the growth of urban population. Although, cities continue to develop and purify their social, economic and environmental goals along with the strategies to achieve them, this phenomenon has been discussed by little research yet. However, due to the requiring immediate action or attention for practical application of the principles of smart cities, city authorities, stakeholders and local communities need to know the current reality of their city and where development is being attained in their systems. Therefore, constructing a framework for smart cities assessment will help share or exchange the newcomer strong and weak points, and emphasize where actual development is taking place and update a plan for future developments. Moreover, this assessment is able to assist cities prioritizes actions. This paper developed a guiding assessment framework for smart cites that will help the creating, carefully choosing and priorities of crucial indicators. These indicators can then show the way to the smart cites performance assessment and monitoring. Drawing on the investigation of an extensive and wide collection of literature from a variety of disciplinary areas and based on the conceptual literature on smart cities, in addition to interviews this study identify a good tool to help recognizing of virtual achievement of smart city. Furthermore, it is significant to be taken into consideration in assessing smart city smartness level.