WorldWideScience

Sample records for releases complex meteorological

  1. Mesoscale meteorological measurements characterizing complex flows

    International Nuclear Information System (INIS)

    Hubbe, J.M.; Allwine, K.J.

    1993-09-01

    Meteorological measurements are an integral and essential component of any emergency response system for addressing accidental releases from nuclear facilities. An important element of the US Department of Energy's (DOE's) Atmospheric Studies in Complex Terrain (ASCOT) program is the refinement and use of state-of-the-art meteorological instrumentation. ASCOT is currently making use of ground-based remote wind sensing instruments such as doppler acoustic sounders (sodars). These instruments are capable of continuously and reliably measuring winds up to several hundred meters above the ground, unattended. Two sodars are currently measuring the winds, as part of ASCOT's Front Range Study, in the vicinity of DOE's Rocky Flats Plant (RFP) near Boulder, Colorado. A brief description of ASCOT's ongoing Front Range Study is given followed by a case study analysis that demonstrates the utility of the meteorological measurement equipment and the complexity of flow phenomena that are experienced near RFP. These complex flow phenomena can significantly influence the transport of the released material and consequently need to be identified for accurate assessments of the consequences of a release

  2. Transport of radionuclides in the atmosphere during complex meteorological conditions

    International Nuclear Information System (INIS)

    Antic, D.; Telenta, B.

    1991-01-01

    Radionuclides from various sources (nuclear and fossil fuel power plants, nuclear facilities, medical facilities, etc.) are being released to the atmosphere. The meteorological conditions determine the atmospheric turbulence, dispersion, and removal processes of the radionuclides. A two-dimensional version of the cloud model based on the Klemp-Wilhelmson dynamic and Lin et al.'s microphysics and thermodynamics has been adapted and used to simulate the transport of radionuclides emitted from a power plant or other source to the atmosphere. Calculations of the trajectories and radii for a few puffs are included in this paper. These numerical investigations show that the presented model can be used for the transport simulation of radionuclides and for the assessment of the radiological impact of power plants and other sources in safety assessments and comparative studies. Because it can simulate puff trajectories, this model is especially valuable in the presence of complex meteorological conditions

  3. Meso-meteorological effect of thermal releases from nuclear power plants in the GW range

    International Nuclear Information System (INIS)

    Bahloul, C.; Le Berre, P.

    1975-01-01

    A comparison is made between the energy released by nuclear power plants into the environment and the energy brought into action by meso-meteorological phenomena. Observations on the occasion of important heat release (forest fires) are made and compared with the thermal effluents generated by nuclear power plants [fr

  4. The variation of health effects based on the scenarios considering release parameters and meteorological data

    International Nuclear Information System (INIS)

    Jeong, Jong Tae; Ha, Jae Joo

    2000-01-01

    The variation of health effects resulting from the severe accidents of the YGN 3 and 4 nuclear power plants was examined based on scenarios considering the release parameters and meteorological data. The release parameters and meteorological data considered in making basic scenarios are release height, heat content, release time, warning time, wind speed, rainfall rate, and atmospheric stability class. The seasonal scenarios were also made in order to estimate the seasonal variation of health effects by considering seasonal characteristics of Korea. According to the results, there are large differences in consequence analysis from scenario to although an equal amount of radioactive materials is released to the atmosphere. Also, there are large differences in health effects from season to season due to distinct seasonal characteristics of Korea. Therefore, it is necessary to consider seasonal characteristics in developing optimum emergency response strategies

  5. The estimation of early health effects for different combinations of release parameters and meteorological data

    International Nuclear Information System (INIS)

    Jeong, Jong Tae; Jung, Won Dea

    2001-01-01

    Variations in the number of early health effects resulting from the severe accidents of the YGN 3 and 4 nuclear power plants were examined for different combinations of release parameters and meteorological data. The release parameters and meteorological data were selected in combination to define a limited number of basic spectra characterized by release height, heat content, release time, warning time, wind speed, rainfall rate, and atmospheric stability class. Variant seasonal spectra were also defined in order to estimate the potential significance of seasonal variations as a factor determining the incidence or number of early health effects. The results show that there are large differences in consequences from spectrum to spectrum, although an equal amount and mix of radioactive material is released to the atmosphere in each case. Also, there are large differences in the estimated number of health effects from season to season due to distinct seasonal variations in meteorological combinations in Korea. Therefore, it is necessary to consider seasonal characteristics in developing optimum emergency response strategies

  6. Meteorological Effects of Thermal Energy Releases (METER) Program. Annual progress report, October 1978-September 1979

    International Nuclear Information System (INIS)

    Patrinos, A.A.N.; Hoffman, H.W.

    1980-04-01

    The METER (Meteorological Effects of Thermal Energy Releases) Program was organized to develop and verify methods for predicting the maximum amount of energy that can be dissipated to the atmosphere (through cooling towers or cooling ponds) from proposed nuclear energy centers without affecting...the local and regional environment. The initial program scope (mathematical modeling, laboratory and field experimentation, and societal impact assessment) has now narrowed to emphasis on the acquisition of field data of substantial quality and extent

  7. Meteorological conditions at the release site during the two tracer experiments

    DEFF Research Database (Denmark)

    Gryning, Sven-Erik; Batchvarova, E.; Schneiter, D.

    1998-01-01

    The state of the boundary layer at the release site during the two tracer experiments is described, based on measurements of atmospheric turbulence carried our by a sonic anemometer, profiles of horizontal and vertical wind by a SODAR as well as frequent radiosonde releases. The boundary layer...... height is derived from radiosoundings, modelled and discussed. The study is meant as background for discussions of the tracer behaviour near the release site, and possible influence of the local meteorology at the release site on the long-range dispersion. The difference in the initial mese...... model development. It is concluded that the micrometeorological measurements are very important as background information for the understanding of plume behaviour on small as well as long scales. (C) 1998 Elsevier Science Ltd. All rights reserved....

  8. Overall analysis of meteorological information in the Daeduk nuclear complex

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byung Woo; Lee, Young Bok; Han, Moon Hee; Kim, Eun Han; Suh, Kyung Suk; Hwang, Won Tae [Korea Atomic Energy Res. Inst., Taejon (Korea, Republic of)

    1994-01-01

    Inspection and repair of tower structure and lift, instrument calibration have been done with DAS (data aquisition system) updating. Wind direction, wind speed, temperature, humidity at 67m, 27m, and 10m height and temperature, humidity, atmospheric pressure, solar radiation, precipitation, and visibility at surface have been measured and analyzed with statistical methods. Wireless data transmission to MIPS (Meteorological Information Processing System) has been done after collection in the DAS where enviromental assessment can be done by the developed simulation programs in both cases of normal operation and emergency. The meteorological data as the result of this project had been used to report `Environmental Impact Assessment of the Korean Multi-purpose Research Reactor` and {sup S}ite Selection of Meteorological Tower and Environment Impact Assessment of the Cooling Tower of the Korean Multi-purpose Research Reactor{sup .} (Author).

  9. Applications of complex terrain meteorological models to emergency response management

    International Nuclear Information System (INIS)

    Yamada, Tetsuji; Leone, J.M. Jr.; Rao, K.S.; Dickerson, M.H.; Bader, D.C.; Williams, M.D.

    1989-01-01

    The Office of Health and Environmental Research (OHER), US Department of Energy (DOE), has supported the development of mesoscale transport and diffusion and meteorological models for several decades. The model development activities are closely tied to the OHER field measurement program which has generated a large amount of meteorological and tracer gas data that have been used extensively to test and improve both meteorological and dispersion models. This paper briefly discusses the history of the model development activities associated with the OHER atmospheric science program. The discussion will then focus on how results from this program have made their way into the emergency response community in the past, and what activities are presently being pursued to improve real-time emergency response capabilities. Finally, fruitful areas of research for improving real-time emergency response modeling capabilities are suggested. 35 refs., 5 figs

  10. Micro-meteorological data from the Guardo dispersion experiment in complex terrain

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, M.; Mikkelsen, T.

    1992-11-01

    The present report contains micrometeorological data from an atmospheric dispersion experiment in complex terrain. The experiment took place near the Guardo power plant, Palencia, Spain under various atmospheric conditions during the month of November 1990. It consisted of 14 tracer releases either from the power plant chimney or from the valley floor north of the town. Two kinds of observations are presented: (1) The 25 m meteorological mast at the Vivero site in the central part of the experimental area measured surface-layer profiles of wind velocity, wind direction, temperature and thermal stability together with turbulent wind and temperature fluctuations at the top level. (2) A radiosonde on a tethered balloon was launched at Camporredondo de Alba in the northern part of the area and measured boundary-layer profiles of pressure, temperature, humidity, wind speed and wind direction. (au) (4 tabs., 227 ills., 7 refs.).

  11. Overall analysis of meteorological information in the Daeduk nuclear complex

    International Nuclear Information System (INIS)

    Kim, Eun Han; Lee, Yung Bok; Han, Moon Heui; Suh, Kyung Suk; Hwang Won Tae

    1995-01-01

    Inspection and repair of tower structure and lift, instrument calibration have been done. Wireless data transmission to MIPS(Meteorological Information Processing System) has been done after collection in the DAS where environmental assessment can be done by the developed simulation programs in both cases of normal operation and emergency. Wind direction, wind speed, temperature, humidity, at 67 m, 27 m, and 10 m height and temperature, humidity, atmospheric pressure, solar radiation, precipitation, and visibility at surface have been measured and analyzed with statistical methods. At the site, the prevailing wind directions were SW in spring and summer, N and NW in autumn and winter season. The calm distributed 13.6% at 67 m, 24.5% at 27 m, 40.8% at 10 m height. 4 figs, 9 tabs, 6 refs. (Author)

  12. Overall analysis of meteorological information in the Daeduk nuclear complex

    Energy Technology Data Exchange (ETDEWEB)

    Han, Moon Hee; Lee, Young Bok; Kim, Eun Han; Seo, Kyung Seok; Hwang, Wan Tae [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-12-01

    Inspection and repair of tower structure and lift, instrument calibration have been done. Wireless data transmission to MIPS(Meteorological Information Processing System) has been done after collection in the DAS where environmental assessment can be done by the developed simulation programs in both cases of normal operation and emergency. Wind direction, wind speed, temperature, humidity at 67m, 27m, and 10m height and temperature, humidity, atmospheric pressure, solar radiation, precipitation, and visibility at surface have been measured and analyzed with statistical methods. At the site, the prevailing wind directions were SW in spring and summer, NNW in winter season. The calm distributed 28.6% at 67m, 20.5% at 27m, 39.2% at 10m height. 9 tabs., 4 figs., 6 refs. (Author).

  13. Overall analysis of meteorological information in the Daeduk nuclear complex

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Han; Lee, Yung Bok; Han, Moon Heui; Suh, Kyung Suk; Tae, Hwang Won [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-01-01

    Inspection and repair of tower structure and lift, instrument calibration have been done. Wireless data transmission to MIPS(Meteorological Information Processing System) has been done after collection in the DAS where environmental assessment can be done by the developed simulation programs in both cases of normal operation and emergency. Wind direction, wind speed, temperature, humidity, at 67 m, 27 m, and 10 m height and temperature, humidity, atmospheric pressure, solar radiation, precipitation, and visibility at surface have been measured and analyzed with statistical methods. At the site, the prevailing wind directions were SW in spring and summer, N and NW in autumn and winter season. The calm distributed 13.6% at 67 m, 24.5% at 27 m, 40.8% at 10 m height. 4 figs, 9 tabs, 6 refs. (Author).

  14. Overall analysis of meteorological information in the daeduk nuclear complex

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byung Woo; Lee, Young Bok; Han, Moon Hee; Kim, Eun Han; Suh, Kyung Suk; Hwang, Won Tae; Hong, Suk Boong [Korea Atomic Energy Res. Inst., Taejon (Korea, Republic of)

    1992-12-01

    Problem shooting in tower structure, sensor installation, earth, and cabling have been done with integrated field-test, establishment of data acquisition system, and instrument calibration since the completion of the main tower construction in this year. Procedure guide was also made for the effective management covering instrument operation, calibration and repair. Real measurement has been done during two months from this October after whole integration of equipments. Occurrence of nocturnal inversion layer, fogging, and frequent stable condition of atmospheric stability were shown as the analysis results of measured data which well represented seasonal and regional characteristics in the site. Wireless data transmission to MIPS(Meteorological Information Processing System) has been done after collection in the DAS(data acquision system) where environmental assessment can be done by the developed simulation programs in both cases of normal operation and emergency. (Author).

  15. Results of development and field tests of a radar-tracer system providing meteorological support to modeling hazardous technological releases

    International Nuclear Information System (INIS)

    Shershakov, V.M.; Zukov, G.P.; Kosykh, V.S.

    2003-01-01

    radiation monitoring laboratory and the LDU was on the bank of the cooling pond. The main characteristics of a cloud of substances are standard deviations in the spatial concentration distributions in the cloud along mutually perpendicular directions, which are representative spatial scales of the cloud in these directions. The squares of these values are relative variances of the cloud. These characteristics were the first to determine and are among the most important input parameters in different models assessing transport and dispersion of hazardous substances. Dispersion of a cloud of substances is influenced by turbulence and vertical shifts of the mean wind speed, with the patterns of dispersion being different depending an diffusion time (or distance to a source). The results of the conducted experiments have revealed an important advantage of the used radar complex in terms of support to predictions of possible contamination in case of release of hazardous materials. As the chaff cloud moves with the wind and is dispersed, it echoes the meteorological situation at a given time moment (vertical wind distribution and air temperature, turbulence level, boundary layer thickness, type of underlying surface) and any changes occurring in the conditions on its way. Based on obtained radar data, the radar complex is capable of assessing the dispersion parameters which can then be used in the mathematical transport and dispersion models. What's more, determination of these parameters does not require any meteorological measurements. In addition, using data about movement of the cloud centroid, the wind speed and direction is estimated at the release height by the radar complex itself. The conducted experiments have shown that the developed technology makes possible measuring key parameters of a cloud of substances at the height of dispersion and taking into account local features of the distribution of meteorological quantities occurring in the vicinity of a source. This

  16. Flash release an alternative for releasing complex MEMS devices

    NARCIS (Netherlands)

    Deladi, S.; Krijnen, Gijsbertus J.M.; Elwenspoek, Michael Curt

    2004-01-01

    A novel time-saving and cost-effective release technique has been developed and is described. The physical nature of the process is explained in combination with experimental observations. The results of the flash release process are compared with those of freeze-drying and supercritical CO2

  17. Impact of atmospheric release in stable night meteorological conditions; can emergency models predict dispersion

    Energy Technology Data Exchange (ETDEWEB)

    Connan, O.; Hebert, D.; Solier, L.; Voiseux, C.; Lamotte, M.; Laguionie, P.; Maro, D.; Thomas, L. [IRSN/PRP-ENV/SERIS/LRC (France)

    2014-07-01

    Atmospheric dispersion of pollutant or radionuclides in stratified meteorological condition, i.e. especially when weather conditions are very stable, mainly at night, is still poorly understood and not well apprehended by the operational atmospheric dispersion models. However, correctly predicting the dispersion of a radioactive plume, and estimating the radiological consequences for the population, following an unplanned atmospheric release of radionuclides are crucial steps in an emergency response. To better understand dispersion in these special weather conditions, IRSN performed a series of 22 air sampling campaigns between 2010 and 2013 in the vicinity of the La Hague nuclear reprocessing plant (AREVA - NC, France), at distances between 200 m and 3000 m from the facility. Krypton-85 ({sup 85}Kr), a b-and g-emitting radionuclide, released during the reprocessing of spent nuclear fuel was used as a non-reactive tracer of radioactive plumes. Experimental campaigns were realized in stability class stable or very stable (E or F according to Pasquill classification) 18 times, and in neutral conditions (D according to Pasquill classification) 4 times. During each campaign, Krypton-85 real time measurement were made to find the plume around the plant, and then integrated samples (30 min) were collected in bag perpendicularly to the assumed wind direction axis. After measurement by gamma spectrometry, we have, when it was possible, estimate the point of impact and the width of the plume. The objective was to estimate the horizontal dispersion (width) of the plume at ground level in function of the distance and be able to calculate atmospheric transfer coefficients. In a second step, objective was to conclude on the use of common model and on their uncertainties. The results will be presented in terms of impact on the near-field. They will be compared with data obtained in previous years in neutral atmospheric conditions, and finally the results will be confronted with

  18. The radiological consequences of notional accidental releases of radioactivity from fast breeder reactors: the influence of the meteorological conditions

    International Nuclear Information System (INIS)

    Hemming, C.R.; Hallam, J.; Kelly, G.N.

    1980-04-01

    The radiological consequences of a wide range of notional accidental releases from a 1300 MW(e) LMFBR (liquid Metal-cooled Fast Breeder Reactor) were assessed in a previous study by the National Radiological Protection Board. In the present study the sensitivity of the predicted consequences to the meteorological conditions was investigated. The influence of the wind direction, and hence the distribution of the exposed population, and of atmospheric stability at the time of the release are considered separately. Conclusions are reached on the precision required in specifying atmospheric stability conditions to estimate reliably the distribution of possible consequences following a given release of activity. The probability distributions of consequences for selected releases from two locations are evaluated taking account of the frequency distribution of wind direction and atmospheric stability at each location. The variation is large and demonstrates the importance of taking account of the whole range of meteorological conditions when assessing the risk presented by an accidental release of activity. (author)

  19. Real-time modeling of complex atmospheric releases in urban areas

    International Nuclear Information System (INIS)

    Baskett, R.L.; Ellis, J.S.; Sullivan, T.J.

    1994-08-01

    If a nuclear installation in or near an urban area has a venting, fire, or explosion, airborne radioactivity becomes the major concern. Dispersion models are the immediate tool for estimating the dose and contamination. Responses in urban areas depend on knowledge of the amount of the release, representative meteorological data, and the ability of the dispersion model to simulate the complex flows as modified by terrain or local wind conditions. A centralized dispersion modeling system can produce realistic assessments of radiological accidents anywhere in a country within several minutes if it is computer-automated. The system requires source-term, terrain, mapping and dose-factor databases, real-time meteorological data acquisition, three-dimensional atmospheric transport and dispersion models, and experienced staff. Experience with past responses in urban areas by the Atmospheric Release Advisory Capability (ARAC) program at Lawrence Livermore National Laboratory illustrate the challenges for three-dimensional dispersion models

  20. Real-time modelling of complex atmospheric releases in urban areas

    International Nuclear Information System (INIS)

    Baskett, R.L.; Ellis, J.S.; Sullivan, T.J.

    2000-01-01

    If a nuclear installation in or near an urban area has a venting, fire, or explosion, airborne radioactivity becomes the major concern. Dispersion models are the immediate tool for estimating the dose and contamination. Responses in urban areas depend on knowledge of the amount of the release, representative meteorological data, and the ability of the dispersion model to simulate the complex flows as modified by terrain or local wind conditions. A centralised dispersion modelling system can produce realistic assessments of radiological accidents anywhere in a country within several minutes if it is computer-automated. The system requires source-term, terrain, mapping and dose-factor databases, real-time meteorological data acquisition, three-dimensional atmospheric transport and dispersion models, and experienced staff. Experience with past responses in urban areas by the Atmospheric Release Advisory Capability (ARAC) program at Lawrence Livermore National Laboratory illustrate the challenges for three-dimensional dispersion models. (author)

  1. XOQDOQ: computer program for the meteorological evaluation of routine effluent releases at nuclear power stations. Final report

    International Nuclear Information System (INIS)

    Sagendorf, J.F.; Goll, J.T.; Sandusky, W.F.

    1982-09-01

    Provided is a user's guide for the US Nuclear Regulatory Commission's (NRC) computer program X0QDOQ which implements Regulatory Guide 1.111. This NUREG supercedes NUREG-0324 which was published as a draft in September 1977. This program is used by the NRC meteorology staff in their independent meteorological evaluation of routine or anticipated intermittent releases at nuclear power stations. It operates in a batch input mode and has various options a user may select. Relative atmospheric dispersion and deposition factors are computed for 22 specific distances out to 50 miles from the site for each directional sector. From these results, values for 10 distance segments are computed. The user may also select other locations for which atmospheric dispersion deposition factors are computed. Program features, including required input data and output results, are described. A program listing and test case data input and resulting output are provided

  2. Consequences of varied soil hydraulic and meteorological complexity on unsaturated zone time lag estimates.

    Science.gov (United States)

    Vero, S E; Ibrahim, T G; Creamer, R E; Grant, J; Healy, M G; Henry, T; Kramers, G; Richards, K G; Fenton, O

    2014-12-01

    The true efficacy of a programme of agricultural mitigation measures within a catchment to improve water quality can be determined only after a certain hydrologic time lag period (subsequent to implementation) has elapsed. As the biophysical response to policy is not synchronous, accurate estimates of total time lag (unsaturated and saturated) become critical to manage the expectations of policy makers. The estimation of the vertical unsaturated zone component of time lag is vital as it indicates early trends (initial breakthrough), bulk (centre of mass) and total (Exit) travel times. Typically, estimation of time lag through the unsaturated zone is poor, due to the lack of site specific soil physical data, or by assuming saturated conditions. Numerical models (e.g. Hydrus 1D) enable estimates of time lag with varied levels of input data. The current study examines the consequences of varied soil hydraulic and meteorological complexity on unsaturated zone time lag estimates using simulated and actual soil profiles. Results indicated that: greater temporal resolution (from daily to hourly) of meteorological data was more critical as the saturated hydraulic conductivity of the soil decreased; high clay content soils failed to converge reflecting prevalence of lateral component as a contaminant pathway; elucidation of soil hydraulic properties was influenced by the complexity of soil physical data employed (textural menu, ROSETTA, full and partial soil water characteristic curves), which consequently affected time lag ranges; as the importance of the unsaturated zone increases with respect to total travel times the requirements for high complexity/resolution input data become greater. The methodology presented herein demonstrates that decisions made regarding input data and landscape position will have consequences for the estimated range of vertical travel times. Insufficiencies or inaccuracies regarding such input data can therefore mislead policy makers regarding

  3. Meteorological and sulphur dioxide dispersion modelling for an industrial complex near Mexico city metropolitan area

    International Nuclear Information System (INIS)

    Mora, V.R.; Sosa, G.; Molina, M.M.; Palmerin-ruiz, M.E.; Melgarejo-flores, L.E.

    2009-01-01

    Major sulphur dioxide emissions in Mexico are due largely to fuel of oil refining and coal combustion. In Tula-Vito-Apasco industrial corridor (TVA) are located two important sources of SO/sub 2/: the 'Miguel Hidalgo' refinery and the 'Francisco Perez Rios' power plant. Due to from March 25 to April 22 of 2006 a major field campaign took place as part of a collaborative research program called MILAGRO. Data collected around the Industrial Complex were used to: a) evaluate the air quality to local and regional scale; b) study the structure of the atmospheric boundary layer (BL); and c) validate meteorological and dispersion models. In this study we presented the behaviour of daytime BL, and the results of meteorological and dispersion modelling for selected episodes of high sulfur dioxide (SO/sub 2/). The Regional Atmospheric Modeling System (RAMS) and the Hybrid and Particle Concentration Transport Model (HYPACT) were used to evaluate the impact of SO/sub 2/ emissions to regional scale. For modelling, we selected the days where higher mean daily levels of SO/sub 2 /surface concentrations were observed, these corresponded to March 31 and April 6. The results indicate that: The daytime BL in TVA, exhibited a normal behavior, a stable layer or thermal inversion close to surface was observed at 0800 LST (up to 80% of the cases), then the mixing height (MH) growths, with a growth rate of 313 m h-1 (between 0800 to 1200 LST). The most rapid MH growth happened between 1200 to 1500 LST;. The maximum MH was observed at 1500 LST (90% of the cases); the mean maximum MH was close to 2794 m AGL; Potential temperature and humidity profiles showed a normal behavior; High persistence in wind direction (> 0.6) close to surface up to 500 m AGL, was observed at 1500, and 1800 LST, at the same time, a low level jet, penetrating from the NE, with wind speed between 6 to 8 m s/sup -1/ was observed. Meteorological modelling was used to determine the circulation patterns in the region

  4. Algorithmic complexity of growth hormone release in humans

    Energy Technology Data Exchange (ETDEWEB)

    Prank, K.; Wagner, M.; Brabant, G. [Medical School Hannover (Germany)

    1996-12-31

    Most hormones are secreted in an pulsatile rather than in a constant manner. This temporal pattern of pulsatile hormone release plays an important role in the regulation of cellular function and structure. In healthy humans growth hormone (GH) secretion is characterized by distinct pulses whereas patients bearing a GH producing tumor accompanied with excessive secretion (acromegaly) exhibit a highly irregular pattern of GH release. It has been hypothesized that this highly disorderly pattern of GH release in acromegaly arises from random events in the GH-producing tumor under decreased normal control of GH secretion. Using a context-free grammar complexity measure (algorithmic complexity) in conjunction with random surrogate data sets we demonstrate that the temporal pattern of GH release in acromegaly is not significantly different from a variety of stochastic processes. In contrast, normal subjects clearly exhibit deterministic structure in their temporal patterns of GH secretion. Our results support the hypothesis that GH release in acromegaly is due to random events in the GH-producing tumorous cells which might become independent from hypothalamic regulation. 17 refs., 1 fig., 2 tabs.

  5. The Effects of Anthropogenic Heat Release on Urban Meteorology and Implication for Haze Pollution in the Beijing-Tianjin-Hebei Region

    Directory of Open Access Journals (Sweden)

    Ruiting Liu

    2016-01-01

    Full Text Available In this study, the effect of anthropogenic heat release (AHR on meteorological variables and atmospheric diffusion capability and implication for haze pollution in the Beijing-Tianjin-Hebei region in January 2013 were investigated by using Weather Research and Forecasting (WRF model with an urban canopy model (UCM and an AHR scheme. The comparison with observation demonstrated the WRF/UCM model taking AHR into account apparently improved meteorological prediction, especially for surface air temperature at 2 m (T2. The model also exhibited a better performance for planetary boundary layer (PBL height. This study revealed that AHR from cities exerted a significant impact on meteorology by generally increasing surface air temperature and wind speed, decreasing relative humidity, and elevating PBL height and near surface turbulent kinetic energy (TKE, which could consequently reduce surface pollutant concentration and mitigate haze pollution by enhancing atmospheric instability and turbulent mixing and reducing aerosol hygroscopic growth.

  6. A database on tritium behavior in the chronic HT release experiment. 1. Meteorological data and tritium concentrations in air and soil

    Energy Technology Data Exchange (ETDEWEB)

    Noguchi, Hiroshi; Yokoyama, Sumi; Kinouchi, Nobuyuki; Murata, Mikio; Amano, Hikaru; Ando, Mariko [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Fukutani, Satoshi

    1999-03-01

    This report comprises a database that can be used to develop and validate tritium models to assess doses to the general public due to HT continuously released from fusion facilities into the atmosphere. The data was collected in the 1994 chronic HT release experiment carried out at the Chalk River Laboratories in Canada. The data set include meteorological conditions such as solar radiation, net solar radiation, wind speed, air temperature and humidity, soil temperature and soil heat flux; soil conditions such as bulk density, water content and free pore volume fraction; HT and HTO concentrations in air, HTO concentrations in soil moisture and HTO deposition to water surface. Evapo-transpiration rates and turbulent diffusivity are estimated and tabulated. The report also contains experimental methods to observe meteorological conditions and take air and soil samples. (author)

  7. Improved Meteorological Input for Atmospheric Release Decision support Systems and an Integrated LES Modeling System for Atmospheric Dispersion of Toxic Agents: Homeland Security Applications

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, E; Simpson, M; Larsen, S; Gash, J; Aluzzi, F; Lundquist, J; Sugiyama, G

    2010-04-26

    When hazardous material is accidently or intentionally released into the atmosphere, emergency response organizations look to decision support systems (DSSs) to translate contaminant information provided by atmospheric models into effective decisions to protect the public and emergency responders and to mitigate subsequent consequences. The Department of Homeland Security (DHS)-led Interagency Modeling and Atmospheric Assessment Center (IMAAC) is one of the primary DSSs utilized by emergency management organizations. IMAAC is responsible for providing 'a single piont for the coordination and dissemination of Federal dispersion modeling and hazard prediction products that represent the Federal position' during actual or potential incidents under the National Response Plan. The Department of Energy's (DOE) National Atmospheric Release Advisory Center (NARAC), locatec at the Lawrence Livermore National Laboratory (LLNL), serves as the primary operations center of the IMAAC. A key component of atmospheric release decision support systems is meteorological information - models and data of winds, turbulence, and other atmospheric boundary-layer parameters. The accuracy of contaminant predictions is strongly dependent on the quality of this information. Therefore, the effectiveness of DSSs can be enhanced by improving the meteorological options available to drive atmospheric transport and fate models. The overall goal of this project was to develop and evaluate new meteorological modeling capabilities for DSSs based on the use of NASA Earth-science data sets in order to enhance the atmospheric-hazard information provided to emergency managers and responders. The final report describes the LLNL contributions to this multi-institutional effort. LLNL developed an approach to utilize NCAR meteorological predictions using NASA MODIS data for the New York City (NYC) region and demonstrated the potential impact of the use of different data sources and data

  8. A real-time PUFF-model for accidental releases in complex terrain

    International Nuclear Information System (INIS)

    Thykier-Nielsen, S.; Mikkelsen, T.; Larsen, S.E.; Troen, I.; Baas, A.F. de; Kamada, R.; Skupniewicz, C.; Schacher, G.

    1990-01-01

    LINCOM-RIMPUFF, a combined flow/puff model, was developed at Riso National Laboratory for the Vandenberg AFB Meteorology and Plume Dispersion Handbook and is suitable as is for real time response to emergency spills and vents of gases and radionuclides. LINCOM is a linear, diagnostic, spectral, potential flow model which extends the Jackson-Hunt theory of non-hydrostatic, adiabatic wind flow over hills to the mesoscale domain. It is embedded in a weighted objective analysis (WOA) of real-time Vandenberg tower winds and may be used in ultra-high speed lookup table mode. The mesoscale dispersion model RIMPUFF is a flexible Gaussian puff model equipped with computer-time effective features for terrain and stability-dependent dispersion parameterization, plume rise formulas, inversion and ground-level reflection capabilities and wet/dry (source) depletion. It can treat plume bifurcation in complex terrain by using a puff-splitting scheme. It allows the flow-model to compute the larger scale wind field, reserving turbulent diffusion calculations for the sub-grid scale. In diagnostic mode toxic exposure are well assessed via the release of a single initial puff. With optimization, processing time for RIMPUFF should be on the order of 2 CPU minutes or less on a PC-system. In prognostic mode with shifting winds, multiple puff releases may become necessary, thereby lengthening processing time

  9. Meteorological Monitoring Program

    International Nuclear Information System (INIS)

    Hancock, H.A. Jr.; Parker, M.J.; Addis, R.P.

    1994-01-01

    The purpose of this technical report is to provide a comprehensive, detailed overview of the meteorological monitoring program at the Savannah River Site (SRS) near Aiken, South Carolina. The principle function of the program is to provide current, accurate meteorological data as input for calculating the transport and diffusion of any unplanned release of an atmospheric pollutant. The report is recommended for meteorologists, technicians, or any personnel who require an in-depth understanding of the meteorological monitoring program

  10. Meteorological Monitoring Program

    Energy Technology Data Exchange (ETDEWEB)

    Hancock, H.A. Jr. [ed.; Parker, M.J.; Addis, R.P.

    1994-09-01

    The purpose of this technical report is to provide a comprehensive, detailed overview of the meteorological monitoring program at the Savannah River Site (SRS) near Aiken, South Carolina. The principle function of the program is to provide current, accurate meteorological data as input for calculating the transport and diffusion of any unplanned release of an atmospheric pollutant. The report is recommended for meteorologists, technicians, or any personnel who require an in-depth understanding of the meteorological monitoring program.

  11. Simulation of tracer dispersion from elevated and surface releases in complex terrain

    Science.gov (United States)

    Hernández, J. F.; Cremades, L.; Baldasano, J. M.

    A new version of an advanced mesoscale dispersion modeling system for simulating passive air pollutant dispersion in the real atmospheric planetary boundary layer (PBL), is presented. The system comprises a diagnostic mass-consistent meteorological model and a Lagrangian particle dispersion model (LADISMO). The former version of LADISMO, developed according to Zannetti (Air pollution modelling, 1990), was based on the Monte Carlo technique and included calculation of higher-order moments of vertical random forcing for convective conditions. Its ability to simulate complex flow dispersion has been stated in a previous paper (Hernández et al. 1995, Atmospheric Environment, 29A, 1331-1341). The new version follows Thomson's scheme (1984, Q. Jl Roy. Met. Soc.110, 1107-1120). It is also based on Langevin equation and follows the ideas given by Brusasca et al. (1992, Atmospheric Environment26A, 707-723) and Anfossi et al. (1992, Nuovo Cemento 15c, 139-158). The model is used to simulate the dispersion and predict the ground level concentration (g.l.c.) of a tracer (SF 6) released from both an elevated source ( case a) and a ground level source ( case b) in a highly complex mountainous terrain during neutral and synoptically dominated conditions ( case a) and light and apparently stable conditions ( case b). The last case is considered as being a specially difficult task to simulate. In fact, few works have reported situations with valley drainage flows in complex terrains and real stable atmospheric conditions with weak winds. The model assumes that nearly calm situations associated to strong stability and air stagnation, make the lowest layers of PBL poorly diffusive (Brusasca et al., 1992, Atmospheric Environment26A, 707-723). Model results are verified against experimental data from Guardo-90 tracer experiments, an intensive field campaign conducted in the Carrion river valley (Northern Spain) to study atmospheric diffusion within a steep walled valley in mountainous

  12. Stress accumulation and release at complex transform plate boundaries

    Energy Technology Data Exchange (ETDEWEB)

    Verdonck, D.; Furlong, K.P. (Pennsylvania State Univ., University Park (United States))

    1992-10-01

    Finite element methods are used to model the dynamics of deformation along complex transform plate boundaries, specifically the San Andreas fault system, California. Effects of mantle rheology and fault geometry on the stress buildup and release are investigated. No prior knowledge of the earthquake cycle time or amount of fault slip is assumed that the results suggest that the San Andreas fault slips at low shear stress (about 15 MPa). Although the maximum stress on the fault is 15 MPa, models with an upper mantle shear zone deforming entirely by dislocation creep accumulate stresses that exceed 100 MPa, a stress level high enough to drive localized dynamic recrystallization and a shift in dominant deformation mechanism to diffusion creep. Models in which the mantle shear zone deform locally by diffusion creep reach a dynamic steady state where lithospheric shear stresses never exceed the specified fault stress anywhere in the model and indicate that the strength of the upper mantle is an important parameter in the dynamics of plate boundary deformation. 17 refs.

  13. Normalization of informatisation parameter on airfield light-signal bar at flights in complex meteorological conditions

    Directory of Open Access Journals (Sweden)

    П.В. Попов

    2005-03-01

    Full Text Available  The technique of maintenance of the set level of flights safetivness is developed by normalization of informatisation parameters functional groups of light-signal lightings at technological stages of interaction of crew of the airplane with the airfield light-signals bar at flights in a complex weathercast conditions.

  14. Motivational Meteorology.

    Science.gov (United States)

    Benjamin, Lee

    1993-01-01

    Describes an introductory meteorology course for nonacademic high school students. The course is made hands-on by the use of an educational software program offered by Accu-Weather. The program contains a meteorology database and instructional modules. (PR)

  15. Smoke Dispersion Modeling Over Complex Terrain Using High-Resolution Meteorological Data and Satellite Observations: The FireHub Platform

    Science.gov (United States)

    Solomos, S.; Amiridis, V.; Zanis, P.; Gerasopoulos, E.; Sofiou, F. I.; Herekakis, T.; Brioude, J.; Stohl, A.; Kahn, R. A.; Kontoes, C.

    2015-01-01

    A total number of 20,212 fire hot spots were recorded by the Moderate Resolution Imaging Spectroradiometer (MODIS) satellite instrument over Greece during the period 2002e2013. The Fire Radiative Power (FRP) of these events ranged from 10 up to 6000 MW at 1 km resolution, and many of these fire episodes resulted in long-range transport of smoke over distances up to several hundred kilometers. Three different smoke episodes over Greece are analyzed here using real time hot-spot observations from the Spinning Enhanced Visible and Infrared Imager (SEVIRI) satellite instrument as well as from MODIS hot-spots. Simulations of smoke dispersion are performed with the FLEXPART-WRF model and particulate matter emissions are calculated directly from the observed FRP. The modeled smoke plumes are compared with smoke stereo-heights from the Multiangle Imaging Spectroradiometer (MISR) instrument and the sensitivities to atmospheric and modeling parameters are examined. Driving the simulations with high resolution meteorology (4 4 km) and using geostationary satellite data to identify the hot spots allows the description of local scale features that govern smoke dispersion. The long-range transport of smoke is found to be favored over the complex coastline environment of Greece due to the abrupt changes between land and marine planetary boundary layers (PBL) and the decoupling of smoke layers from the surface.

  16. Gastrin release: Antrum microdialysis reveals a complex neural control

    DEFF Research Database (Denmark)

    Ericsson, P; Håkanson, R; Rehfeld, Jens F.

    2010-01-01

    in both serum and microdialysate. Food intake induced a 2- to 3-fold increase in serum gastrin, while gastrin in antral microdialysate increased 10- to 15-fold. In unilaterally vagotomized rats (fasted, 3 days post-op.), food evoked a prompt peak gastrin release followed by a gradual decline on the intact......We used microdialysis to monitor local gastrin release in response to food, acid blockade and acute vagal excitation. For the first time, gastrin release has been monitored continuously in intact conscious rats in a physiologically relevant experimental setting in a fashion that minimizes...... in serum regardless of the prandial state. The rats were conscious during microdialysis except when subjected to electrical vagal stimulation. Acid blockade (omeprazole treatment of freely fed rats for 4 days), or bilateral sectioning of the abdominal vagal trunks (fasted, 3 days post-op.), raised...

  17. Slow release of tetracycline from a mucoadhesive complex with sucralfate for eradication of Helicobacter pylori.

    Science.gov (United States)

    Higo, Shoichi; Takeuchi, Hirofumi; Yamamoto, Hiromitsu; Hino, Tomoaki; Kawashima, Yoshiaki

    2008-10-01

    Treatment composed of a gastric mucoadhesive antibiotic with slow release drug delivery is expected to be effective for the eradication of Helicobacter pylori (H. pylori). In this study, we evaluated the slow release property of the tetracycline-sucralfate acidic complex. Tetracycline was the antibiotic selected because of its complexation capacity with sucralfate. Sustained release was tested using two different dissolution test methods: paddle and flow-through cell. The adhesive paste formed from the acidic complex displayed a longer sustained release profile of tetracycline using flow-through cell method. The milder conditions of the flow-through cell method better mimicked the fasted state of the stomach, suggesting that the oral administration with fasting is appropriate for the acidic complex. Furthermore, the paste formation protected the tetracycline from decomposition under an acidic condition, which apparently contributes to long-term release. Change in the zeta potential of the acidic complex particles was helpful in clarifying the release mechanisms of the tetracycline. The data indicated that the immediate release of tetracycline in the early stage of the test was indispensable to the subsequent paste formation that enables slow release. If administrated orally with fasting, the acidic complex rapidly adheres to the gastric mucosa and sustains long-term release of the tetracycline to the gastric lumen or mucus layer. This antibiotic delivery mechanism, which requires only a minimum dosage, may be effective for efficient eradication of H. pylori.

  18. Slow diuron release formulations based on clay-phosphatidylcholine complexes

    Czech Academy of Sciences Publication Activity Database

    Undabeytia, T.; Recio, E.; Maqueda, C.; Sanchez-Verdejo, T.; Balek, Vladimír

    2012-01-01

    Roč. 55, JAN (2012), s. 53-61 ISSN 0169-1317 R&D Projects: GA MŠk(CZ) LC523 Institutional support: RVO:61388980 Keywords : Diuron * Phosphatidylcholine * Clay mineral * Leaching * Bioactivity * Slow release Subject RIV: CA - Inorganic Chemistry OBOR OECD: Inorganic and nuclear chemistry Impact factor: 2.342, year: 2012

  19. An overview of MADONA: A multinational field study of high-resolution meteorology and diffusion over complex terrain

    DEFF Research Database (Denmark)

    Cionco, R.M.; aufm Kampe, W.; Biltoft, C.

    1999-01-01

    The multination, high-resolution field study of Meteorology And Diffusion Over Non-Uniform Areas (MADONA) was conducted by scientists from the United States, the United Kingdom, Germany, Denmark, Sweden, and the Netherlands at Porton Down, Salisbury, Wiltshire, United Kingdom, during September...... and October 1992. The host of the field study was the Chemical and Biological Defence Establishment (CBDE, now part of Defence Evaluation and Research Agency) at Porton Down. MADONA was designed and conducted for high-resolution meteorological data collection and diffusion experiments using smoke......, sulphurhexaflouride (SF6), and propylene gas during unstable, neutral, and stable atmospheric conditions in an effort to obtain terrain-influenced meteorological fields, dispersion, and concentration fluctuation measurements using specialized sensors and tracer generators. Thirty-one days of meteorological data were...

  20. Gastrin release: Antrum microdialysis reveals a complex neural control

    DEFF Research Database (Denmark)

    Ericsson, P; Håkanson, R; Rehfeld, Jens F.

    2010-01-01

    We used microdialysis to monitor local gastrin release in response to food, acid blockade and acute vagal excitation. For the first time, gastrin release has been monitored continuously in intact conscious rats in a physiologically relevant experimental setting in a fashion that minimizes...... in serum regardless of the prandial state. The rats were conscious during microdialysis except when subjected to electrical vagal stimulation. Acid blockade (omeprazole treatment of freely fed rats for 4 days), or bilateral sectioning of the abdominal vagal trunks (fasted, 3 days post-op.), raised...... the gastrin concentration in blood as well as microdialysate. The high gastrin concentration following omeprazole treatment was not affected by vagotomy. Vagal excitation stimulated the G cells: electrical vagal stimulation and pylorus ligation (fasted rats) raised the gastrin concentration transiently...

  1. Meteorology and atomic energy

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    The science of meteorology is useful in providing information that will be of assistance in the choice of favorable plant locations and in the evaluation of significant relations between meteorology and the design, construction, and operation of plant and facilities, especially those from which radioactive or toxic products could be released to the atmosphere. Under a continuing contract with the Atomic Energy Commission, the Weather Bureau has carried out this study. Some of the meteorological techniques that are available are summarized, and their applications to the possible atmospheric pollution deriving from the use of atomic energy are described. Methods and suggestions for the collection, analysis, and use of meteorological data are presented. Separate abstracts are included of 12 chapters in this publication for inclusion in the Energy Data Base

  2. Preparation of a novel breviscapine-loaded halloysite nanotubes complex for controlled release of breviscapine

    Science.gov (United States)

    Gao, Min; Lu, Liqian; Wang, Xiaoyue; Lin, Houke; Zhou, Qingsong

    2017-11-01

    For sustain the release rate and prolong half-life of breviscapine in vivo, the breviscapine-loaded halloysite nanotubes complex was prepared. The breviscapine was encapsulated into halloysite nanotubes (HNTs) using a vacuum process. The complex were investigated by scanning electron microscopy (SEM), differential scanning calorimetry (DSC), transmission electron microscope (TEM), X-ray diffraction (XRD) and fourier transform infrared spectroscopy(FT-IR). The formation of breviscapine-loaded HNTs complex was proved by the test results of SEM, DSC, TEM and IR analysise. The results confirmed that breviscapine was successfully loaded in the halloysite nanotubes. Additionally, the in vitro drug release of breviscapine from breviscapine-loaded HNTs complex was investigated, the result indicated this complex has apparent sustained-release effect.

  3. Meteorological Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Multi-year summaries of one or more meteorological elements at a station or in a state. Primarily includes Form 1078, a United States Weather Bureau form designed...

  4. Meteorology Online.

    Science.gov (United States)

    Kahl, Jonathan D. W.

    2001-01-01

    Describes an activity to learn about meteorology and weather using the internet. Discusses the National Weather Service (NWS) internet site www.weather.gov. Students examine maximum and minimum daily temperatures, wind speed, and direction. (SAH)

  5. NO Exchange for a Water Molecule Favorably Changes Iontophoretic Release of Ruthenium Complexes to the Skin

    Directory of Open Access Journals (Sweden)

    Danielle C. A. S. de Santana

    2017-01-01

    Full Text Available Ruthenium (Ru complexes have been studied as promising anticancer agents. Ru nitrosyl complex (Ru-NO is one which acts as a pro-drug for the release of nitric oxide (NO. The Ru-aqueous complex formed by the exchange of NO for a water molecule after NO release could also possess therapeutic effects. This study evaluates the influence of iontophoresis on enhancing the skin penetration of Ru-NO and Ru-aqueous and assesses its applicability as a tool in treating diverse skin diseases. Passive and iontophoretic (0.5 mA·cm−2 skin permeation of the complexes were performed for 4 h. The amount of Ru and NO in the stratum corneum (SC, viable epidermis (VE, and receptor solution was quantified while the influence of iontophoresis and irradiation on NO release from Ru-NO complex was also evaluated. Iontophoresis increased the amount of Ru-NO and Ru-aqueous recovered from the receptor solution by 15 and 400 times, respectively, as compared to passive permeation. Iontophoresis produced a higher accumulation of Ru-aqueous in the skin layers as compared to Ru-NO. At least 50% of Ru-NO penetrated the SC was stable after 4 h. The presence of Ru-NO in this skin layer suggests that further controlled release of NO can be achieved by photo-stimulation after iontophoresis.

  6. Lateral release of proteins from the TOM complex into the outer membrane of mitochondria.

    Science.gov (United States)

    Harner, Max; Neupert, Walter; Deponte, Marcel

    2011-07-15

    The TOM complex of the outer membrane of mitochondria is the entry gate for the vast majority of precursor proteins that are imported into the mitochondria. It is made up by receptors and a protein conducting channel. Although precursor proteins of all subcompartments of mitochondria use the TOM complex, it is not known whether its channel can only mediate passage across the outer membrane or also lateral release into the outer membrane. To study this, we have generated fusion proteins of GFP and Tim23 which are inserted into the inner membrane and, at the same time, are spanning either the TOM complex or are integrated into the outer membrane. Our results demonstrate that the TOM complex, depending on sequence determinants in the precursors, can act both as a protein conducting pore and as an insertase mediating lateral release into the outer membrane.

  7. Photolabile ruthenium complexes to cage and release a highly cytotoxic anticancer agent.

    Science.gov (United States)

    Wei, Jianhua; Renfrew, Anna K

    2018-02-01

    CHS-828 (N-(6-(4-chlorophenoxy)hexyl)-N'-cyano-N″-4-pyridyl guanidine) is an anticancer agent with low bioavailability and high systemic toxicity. Here we present an approach to improve the therapeutic profile of the drug using photolabile ruthenium complexes to generate light-activated prodrugs of CHS-828. Both prodrug complexes are stable in the dark but release CHS-828 when irradiated with visible light. The complexes are water-soluble and accumulate in tumour cells in very high concentrations, predominantly in the mitochondria. Both prodrug complexes are significantly less cyototoxic than free CHS-828 in the dark but their toxicity increases up to 10-fold in combination with visible light. The cellular responses to light treatment are consistent with release of the cytotoxic CHS-828 ligand. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Modified gum Arabic hydrogels as matrices for controlled release of curcumin supramolecular complexes

    International Nuclear Information System (INIS)

    Gerola, Adriana P.; Silva, Danielle C.; Rubira, Adley F.; Muniz, Edvani C.

    2015-01-01

    Modified gum Arabic (GA) hydrogels show a pH-responsive behavior making them excellent matrices to be used for oral administration of drugs. Our goal is to study the behavior of those matrices in simulated gastric and intestinal fluids. In this work we will present how the methacrylation degree of GA, by using glycidyl methacrylate, can affect the properties of these hydrogels for controlled release. The drug used in this work is the curcumin (Cur). Cur is associated with numerous pharmacological activities, but their application is limited by the low water solubility. We will present some studies involving the formation of host-guest complexes between Cur and natural cyclodextrins. Both modified GA and hydrogels were characterized by different techniques. The kinetics release of Cur complex-containing modified GA hydrogels was studied to have an insight on the release mechanism and rate constants. Toxicity studies on undifferentiated and differentiated Caco-2 were also carried out. (author)

  9. Depolarization-induced release of amino acids from the vestibular nuclear complex.

    Science.gov (United States)

    Godfrey, Donald A; Sun, Yizhe; Frisch, Christopher; Godfrey, Matthew A; Rubin, Allan M

    2012-04-01

    There is evidence from immunohistochemistry, quantitative microchemistry, and pharmacology for several amino acids as neurotransmitters in the vestibular nuclear complex (VNC), including glutamate, γ-aminobutyrate (GABA), and glycine. However, evidence from measurements of release has been limited. The purpose of this study was to measure depolarization-stimulated calcium-dependent release of amino acids from the VNC in brain slices. Coronal slices containing predominantly the VNC were prepared from rats and perfused with artificial cerebrospinal fluid (ACSF) in an interface chamber. Fluid was collected from the chamber just downstream from the VNC using a microsiphon. Depolarization was induced by 50 mM potassium in either control calcium and magnesium concentrations or reduced calcium and elevated magnesium. Amino acid concentrations in effluent fluid were measured by high performance liquid chromatography. Glutamate release increased fivefold during depolarization in control calcium concentration and twofold in low calcium/high magnesium. These same ratios were 6 and 1.5 for GABA, 2 and 1.3 for glycine, and 2 and 1.5 for aspartate. Differences between release in control and low calcium/high magnesium ACSF were statistically significant for glutamate, GABA, and glycine. Glutamine release decreased during and after depolarization, and taurine release slowly increased. No evidence for calcium-dependent release was found for serine, glutamine, alanine, threonine, arginine, taurine, or tyrosine. Our results support glutamate and GABA as major neurotransmitters in the VNC. They also support glycine as a neurotransmitter and some function for taurine.

  10. Platelet 3H-serotonin releasing immune complexes induced by pseudomonas aeruginosa in cystic fibrosis

    International Nuclear Information System (INIS)

    Permin, H.; Stahl Skov, P.; Norn, S.; Hoeiby, N.; Schioetz, P.O.

    1982-01-01

    In vitro formation of immune complexes was studied by 3 H-serotonin release from human platelets by P. aeruginosa antigens in the presence of serum from 22 cyctic fibrosis patients, chronically infected with mucoid P. aeruginosa (CF+P) and with a pronounced antibody response against these bacteria, and in 24 patients without P. aeruginosa (CF-P). All CF+P patients responded with 3 H-serotonin release (16-34%), whereas CF-P patients released less than 15%. In the group of CF+P patients the number of P. aeruginosa precipitins was correlated to the serotonin titer. Time courses indicated that 3 H-serotonin release was maximal between 2 and 5 min, and that no further release was observed up to 20 min. There was a gradual increase in 3 H-serotonin release with higher platelet concentrations. The response was not changed by complement inactivation, and fractionation of serum demonstrated that the serotonin release was dependent on the presence of the immunoglobulin fraction. These experiments support the suggestion of a type III reaction being involved in the lung damage in CF+P patients and also suggest a possible involvement of serotonin in the inflammatory reaction during chronic P. aeruginosa lung infection. (author)

  11. Hydrologic and Meteorological Data for an Unsaturated-Zone Study Area near the Radioactive Waste Management Complex, Idaho National Engineering and Environmental Laboratory, Idaho, 1990-96

    International Nuclear Information System (INIS)

    Perkins, K. S.; Nimmo, J. R.; Pittman, J. R.

    1998-01-01

    Trenches and pits at the Radioactive Waste Management Complex (RWMC) Subsurface Disposal Area (SDA) at the Idaho National Engineering and Environmental Laboratory (formerly known as the Idaho National Engineering Laboratory) have been used for burial of radioactive waste since 1952. In 1985, the U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Energy, began a multi-phase study of the geohydrology of the RWMC to provide a basis for estimating the extent of and the potential for migration of radionuclides in the unsaturated zone beneath the waste trenches and pits. This phase of the study provides hydrologic and meteorological data collected at a designated test trench area adjacent to the northern boundary of the RWMC SDA from 1990 through 1996. The test trench area was constructed by the USGS in 1985. Hydrologic data presented in this report were collected during 1990-96 in the USGS test trench area. Soil-moisture content measurement from disturbed and undisturbed soil were collected approximately monthly during 1990-96 from 11 neutron-probe access holes with a neutron moisture gage. In 1994, three additional neutron access holes were completed for monitoring. A meteorological station inside the test trench area provided data for determination of evapotranspiration rates. The soil-moisture and meteorological data are contained in files on 3-1/2 inch diskettes (disks 1 and 2) included with this report. The data are presented in simple American Standard Code for Information Interchange (ASCII) format with tab-delimited fields. The files occupy a total of 1.5 megabytes of disk space

  12. Complex Regional Pain Syndrome (CRPS Type II After Carpal Tunnel Release Surgery: Case Report

    Directory of Open Access Journals (Sweden)

    Hakan Tunç

    2010-08-01

    Full Text Available Summary Complex regional pain syndrome is a chronic syndrome characterised with dystrophic changes and neurovascular disordes of bone and skin of extremities. The most common etiological factors are trauma, ischemic heart disease, cerebral lesions, servical region disorders, infections, and surgical treatments. Carpal tunnel syndrome is the most common compressive neuropaty of the upper extremity. There are various surgical and conservative alternatives in the treatment of carpal tunnel syndrome. Complex regional pain syndrome has been reported as a complication of surgical carpal tunnel release in 2-5% of patients. In this case report clinical characteristics and rehabilitation outcomes of a patient with complex regional pain syndrome after carpal tunnel release surgery is presented. (Osteoporoz Dünyasından 2010;16:41-3

  13. Hydrological, meteorological and geohydrological data for an unsaturated zone study near the Radioactive Waste Management Complex, Idaho National Engineering Laboratory, Idaho - 1987

    International Nuclear Information System (INIS)

    Davis, L.C.; Pittman, J.R.

    1990-01-01

    Since 1952, radioactive waste has been buried at the RWMC (Radioactive Waste Management Complex) at the Idaho National Engineering Laboratory in southeastern Idaho. In 1985, the US Geological Survey, in cooperation with the US Department of Energy, began a study of the geohydrology of the RWMC to provide a basis for estimating the extent of and the potential for migration of radionuclides in the unsaturated zone beneath the waste burial trenches and pits. This study is being conducted to provide hydrological, meteorological and geohydrological data for the test trench area adjacent to the northern boundary of the RWMC. During 1987, data were collected from the test trench area, where several types of instrumentation were installed in the surficial sediment in 1985. Hydrological data collected from both disturbed and undisturbed soil included measurements, from 28 thermocouple psychrometers placed at selected depths to about 6m. Soil moisture content measurements were collected bi-weekly in 9 neutron-probe access holes with a neutron moisture depth gage. Meteorological data summarized daily included: (1) incoming and emitted long-wave radiation; (2) incoming and reflected short-wave radiation; (3) air temperature; (4) relative humidity; (5) wind speed; (6) wind direction; and (7) precipitation. To describe grain-size distribution with depth, 17 samples were analyzed using sieve and pipette methods. Statistical parameters, carbonate content, color, particle roundness and sphericity, and mineralogic and clastic constituents were determined for each sample. Some samples were analyzed by x-ray diffraction techniques to determine bulk and clay mineralogy

  14. Suppression of grasshopper sound production by nitric oxide-releasing neurons of the central complex

    Science.gov (United States)

    Weinrich, Anja; Kunst, Michael; Wirmer, Andrea; Holstein, Gay R.

    2008-01-01

    The central complex of acridid grasshoppers integrates sensory information pertinent to reproduction-related acoustic communication. Activation of nitric oxide (NO)/cyclic GMP-signaling by injection of NO donors into the central complex of restrained Chorthippus biguttulus females suppresses muscarine-stimulated sound production. In contrast, sound production is released by aminoguanidine (AG)-mediated inhibition of nitric oxide synthase (NOS) in the central body, suggesting a basal release of NO that suppresses singing in this situation. Using anti-citrulline immunocytochemistry to detect recent NO production, subtypes of columnar neurons with somata located in the pars intercerebralis and tangential neurons with somata in the ventro-median protocerebrum were distinctly labeled. Their arborizations in the central body upper division overlap with expression patterns for NOS and with the site of injection where NO donors suppress sound production. Systemic application of AG increases the responsiveness of unrestrained females to male calling songs. Identical treatment with the NOS inhibitor that increased male song-stimulated sound production in females induced a marked reduction of citrulline accumulation in central complex columnar and tangential neurons. We conclude that behavioral situations that are unfavorable for sound production (like being restrained) activate NOS-expressing central body neurons to release NO and elevate the behavioral threshold for sound production in female grasshoppers. PMID:18574586

  15. Bounds on the sample complexity for private learning and private data release

    Energy Technology Data Exchange (ETDEWEB)

    Kasiviswanathan, Shiva [Los Alamos National Laboratory; Beime, Amos [BEN-GURION UNIV.; Nissim, Kobbi [BEN-GURION UNIV.

    2009-01-01

    Learning is a task that generalizes many of the analyses that are applied to collections of data, and in particular, collections of sensitive individual information. Hence, it is natural to ask what can be learned while preserving individual privacy. [Kasiviswanathan, Lee, Nissim, Raskhodnikova, and Smith; FOCS 2008] initiated such a discussion. They formalized the notion of private learning, as a combination of PAC learning and differential privacy, and investigated what concept classes can be learned privately. Somewhat surprisingly, they showed that, ignoring time complexity, every PAC learning task could be performed privately with polynomially many samples, and in many natural cases this could even be done in polynomial time. While these results seem to equate non-private and private learning, there is still a significant gap: the sample complexity of (non-private) PAC learning is crisply characterized in terms of the VC-dimension of the concept class, whereas this relationship is lost in the constructions of private learners, which exhibit, generally, a higher sample complexity. Looking into this gap, we examine several private learning tasks and give tight bounds on their sample complexity. In particular, we show strong separations between sample complexities of proper and improper private learners (such separation does not exist for non-private learners), and between sample complexities of efficient and inefficient proper private learners. Our results show that VC-dimension is not the right measure for characterizing the sample complexity of proper private learning. We also examine the task of private data release (as initiated by [Blum, Ligett, and Roth; STOC 2008]), and give new lower bounds on the sample complexity. Our results show that the logarithmic dependence on size of the instance space is essential for private data release.

  16. Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate.

    LENUS (Irish Health Repository)

    O'Connor, Roisin

    2010-01-01

    Proteomic approaches have proven powerful at identifying large numbers of proteins, but there are fewer reports of functional characterization of proteins in biological tissues. Here, we describe an experimental approach that fractionates proteins released from human platelets, linking bioassay activity to identity. We used consecutive orthogonal separation platforms to ensure sensitive detection: (a) ion-exchange of intact proteins, (b) SDS-PAGE separation of ion-exchange fractions and (c) HPLC separation of tryptic digests coupled to electrospray tandem mass spectrometry. Migration of THP-1 monocytes in response to complete or fractionated platelet releasate was assessed and located to just one of the forty-nine ion-exchange fractions. Over 300 proteins were identified in the releasate, with a wide range of annotated biophysical and biochemical properties, in particular platelet activation, adhesion, and wound healing. The presence of PEDF and involucrin, two proteins not previously reported in platelet releasate, was confirmed by western blotting. Proteins identified within the fraction with monocyte promigratory activity and not in other inactive fractions included vimentin, PEDF, and TIMP-1. We conclude that this analytical platform is effective for the characterization of complex bioactive samples.

  17. Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex

    Energy Technology Data Exchange (ETDEWEB)

    Supavilai, P.; Karobath, M.

    1985-02-04

    GABA, THIP and muscimol enhance spontaneous and inhibit electrically induced release of tritium labelled compounds from rat striatal slices which have been pre-labelled with /sup 3/H-choline. Baclofen is inactive in this model. Muscimol can inhibit electrically induced release of tritiated material by approximately 75% with half maximal effects at 2 ..mu..M. The response to muscimol can be blocked by the GABA antagonists bicuculline methobromide, picrotoxin, anisatin, R 5135 and CPTBO (cyclopentylbicyclophosphate). Drugs which act on the benzodiazepine receptor (BR) require the presence of muscimol to be effective and they modulate the effects of muscimol in a bidirectional manner. Thus BR agonists enhance and inverse BR agonists attenuate the inhibitory effects of muscimol on electrically induced release. Ro15-1788, a BR antagonist, does not modulate the inhibitory effects of muscimol but antagonizes the actions of clonazepam, a BR agonist, and of DMCM, an inverse BR agonist. These results demonstrate that a GABA/benzodiazepine receptor complex can modulate acetylcholine release from rat striatal slices in vitro. 24 references, 3 figures, 5 table.

  18. Tannate complexes of antihistaminic drug: sustained release and taste masking approaches.

    Science.gov (United States)

    Rahman, Ziyaur; Zidan, Ahmed S; Berendt, Robert T; Khan, Mansoor A

    2012-01-17

    The aim of this investigation was to evaluate the complexation potential of brompheniramine maleate (BPM) and tannic acid (TA) for sustained release and taste masking effects. The complexes (1:1-1:7 TA to BPM ratio) were prepared by the solvent evaporation method using methanol, phosphate buffer pH 6.8 or 0.1N HCl as common solvents. The complexes were characterized microscopically by scanning electron microscopy (SEM), chemically by Fourier transform infrared (FTIR) and solid-state NMR (SSNMR), thermally by differential scanning calorimetry (DSC), for crystallinity by powder X-ray powder diffraction (PXRD), for organoleptic evaluation by electronic tongue (e-tongue), and for solubility in 0.1N HCl and phosphate buffer pH 6.8. The dissolution studies were carried out using the USP II method at 50 rpm in 500 ml of dissolution media (0.1N HCl or phosphate buffer pH 6.8). SEM images revealed that the morphology of complexes were completely different from the individual components, and all complexes had the same morphological characteristics, irrespective of the solvent used for their preparation, pH or ratio of BPM and TA. The FTIR spectra showed the presence of chemical interactions between the TA and BPM. DSC, PXRD and SSNMR indicated that the drug lost its crystalline nature by formation of the complex. Complexation has significantly reduced the solubility of BPM and sustained the drug release up to 24h in phosphate buffer pH 6.8 media. The bitter taste of the BPM was completely masked which was indicated by Euclidean distance values which was far from the drug but near to its placebo in the complexes in all ratios studied. The taste masked complexes can be potentially developed as suitable dosage forms for pediatric use. In summary, complexation of BPM and TA effectively sustained the dissolution and masked the bitter taste of drug for the development of suitable dosage forms for pediatric use. Published by Elsevier B.V.

  19. Selective Release of anti–TB Drugs Complex from Smart Copolymeric Bioactive nano–carriers

    Directory of Open Access Journals (Sweden)

    Alejandro Arredondo–Peñaranda

    2014-07-01

    Full Text Available Smart nano–copolymeric matrices have been employed to load and release anti tuberculosis (anti – TB drugs combinated complexes of Ethambutol (EMB, Isoniazid (INH, Rifampicin (RMP and Pyrazinamide (PZA. Copolymeric nanocarriers were synthesized using a microemulsion polymerization method previously reported. These nanocarriers can show selective swelling–collapse response under changes in local environments such a temperature, pH, solvent composition and electrical stimuli. The employ of these kinds of systems permits a controlled and selective delivery and release on specific human tissues. High Performance Liquid Chromatography technique was used to allow the detection of combinated mixtures of different active principles of anti–TB drugs using an acetonitrile mobile phase at 0.5 mL/min of flow rate whit a Spherisorb ODS2, C18 column. The results obtained suggest that the employ of smart nanohydrogels is a novel method in several tuberculosis therapies.

  20. Meteorological instrumentation

    International Nuclear Information System (INIS)

    1982-06-01

    RFS or ''Regles Fondamentales de Surete'' (Basic Safety Rules) applicable to certain types of nuclear facilities lay down requirements with which compliance, for the type of facilities and within the scope of application covered by the RFS, is considered to be equivalent to compliance with technical French regulatory practice. The object of the RFS is to take advantage of standardization in the field of safety , while allowing for technical progress in that field. They are designed to enable the operating utility and contractors to know the rules pertaining to various subjects which are considered to be acceptable by the ''Service Central de Surete des Installations Nucleaires'' or the SCSIN (Central Department for the Safety of Nuclear Facilities). These RFS should make safety analysis easier and lead to better understanding between experts and individuals concerned with the problems of nuclear safety. The SCSIN reserves the right to modify, when considered necessary any RFS and specify, if need be, the terms under which a modification is deemed retroactive. The purpose of this RFS is to specify the meteorological instrumentation required at the site of each nuclear power plant equipped with at least one pressurized water reactor

  1. Airline meteorological requirements

    Science.gov (United States)

    Chandler, C. L.; Pappas, J.

    1985-01-01

    A brief review of airline meteorological/flight planning is presented. The effects of variations in meteorological parameters upon flight and operational costs are reviewed. Flight path planning through the use of meteorological information is briefly discussed.

  2. Diclofenac sodium ion exchange resin complex loaded melt cast films for sustained release ocular delivery.

    Science.gov (United States)

    Adelli, Goutham R; Balguri, Sai Prachetan; Bhagav, Prakash; Raman, Vijayasankar; Majumdar, Soumyajit

    2017-11-01

    The goal of the present study is to develop polymeric matrix films loaded with a combination of free diclofenac sodium (DFS free ) and DFS:Ion exchange resin complexes (DFS:IR) for immediate and sustained release profiles, respectively. Effect of ratio of DFS and IR on the DFS:IR complexation efficiency was studied using batch processing. DFS:IR complex, DFS free , or a combination of DFS free  +   DFS:IR loaded matrix films were prepared by melt-cast technology. DFS content was 20% w/w in these matrix films. In vitro transcorneal permeability from the film formulations were compared against DFS solution, using a side-by-side diffusion apparatus, over a 6 h period. Ocular disposition of DFS from the solution, films and corresponding suspensions were evaluated in conscious New Zealand albino rabbits, 4 h and 8 h post-topical administration. All in vivo studies were carried out as per the University of Mississippi IACUC approved protocol. Complexation efficiency of DFS:IR was found to be 99% with a 1:1 ratio of DFS:IR. DFS release from DFS:IR suspension and the film were best-fit to a Higuchi model. In vitro transcorneal flux with the DFS free  +   DFS:IR (1:1) (1 + 1) was twice that of only DFS:IR (1:1) film. In vivo, DFS solution and DFS:IR (1:1) suspension formulations were not able to maintain therapeutic DFS levels in the aqueous humor (AH). Both DFS free and DFS free  +   DFS:IR (1:1) (3 + 1) loaded matrix films were able to achieve and maintain high DFS concentrations in the AH, but elimination of DFS from the ocular tissues was much faster with the DFS free formulation. DFS free  +   DFS:IR combination loaded matrix films were able to deliver and maintain therapeutic DFS concentrations in the anterior ocular chamber for up to 8 h. Thus, free drug/IR complex loaded matrix films could be a potential topical ocular delivery platform for achieving immediate and sustained release characteristics.

  3. Integration of ambient seismic noise monitoring, displacement and meteorological measurements to infer the temperature-controlled long-term evolution of a complex prone-to-fall cliff

    Science.gov (United States)

    Colombero, C.; Baillet, L.; Comina, C.; Jongmans, D.; Larose, E.; Valentin, J.; Vinciguerra, S.

    2018-06-01

    Monitoring the temporal evolution of resonance frequencies and velocity changes detected from ambient seismic noise recordings can help in recognizing reversible and irreversible modifications within unstable rock volumes. With this aim, the long-term ambient seismic noise data set acquired at the potentially unstable cliff of Madonna delSasso (NW Italian Alps) was analysed in this study, using both spectral analysis and cross-correlation techniques. Noise results were integrated and compared with direct displacement measurements and meteorological data, to understand the long-term evolution of the cliff. No irreversible modifications in the stability of the site were detected over the monitored period. Conversely, daily and seasonal air temperature fluctuations were found to control resonance frequency values, amplitudes and directivities and to induce reversible velocity changes within the fractured rock mass. The immediate modification in the noise parameters due to temperature fluctuations was interpreted as the result of rock mass thermal expansion and contraction, inducing variations in the contact stiffness along the fractures isolating two unstable compartments. Differences with previous case studies were highlighted in the long-term evolution of noise spectral amplitudes and directivities, due to the complex 3-D fracture setting of the site and to the combined effects of the two unstable compartments.

  4. Surface meteorology and Solar Energy

    Science.gov (United States)

    Stackhouse, Paul W. (Principal Investigator)

    The Release 5.1 Surface meteorology and Solar Energy (SSE) data contains parameters formulated for assessing and designing renewable energy systems. Parameters fall under 11 categories including: Solar cooking, solar thermal applications, solar geometry, tilted solar panels, energy storage systems, surplus product storage systems, cloud information, temperature, wind, other meteorological factors, and supporting information. This latest release contains new parameters based on recommendations by the renewable energy industry and it is more accurate than previous releases. On-line plotting capabilities allow quick evaluation of potential renewable energy projects for any region of the world. The SSE data set is formulated from NASA satellite- and reanalysis-derived insolation and meteorological data for the 10-year period July 1983 through June 1993. Results are provided for 1 degree latitude by 1 degree longitude grid cells over the globe. Average daily and monthly measurements for 1195 World Radiation Data Centre ground sites are also available. [Mission Objectives] The SSE project contains insolation and meteorology data intended to aid in the development of renewable energy systems. Collaboration between SSE and technology industries such as the Hybrid Optimization Model for Electric Renewables ( HOMER ) may aid in designing electric power systems that employ some combination of wind turbines, photovoltaic panels, or diesel generators to produce electricity. [Temporal_Coverage: Start_Date=1983-07-01; Stop_Date=1993-06-30] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180].

  5. Characterisation, in vitro release study, and antibacterial activity of montmorillonite-gentamicin complex material

    International Nuclear Information System (INIS)

    Rapacz-Kmita, A.; Bućko, M.M.; Stodolak-Zych, E.; Mikołajczyk, M.; Dudek, P.; nd Department of Surgery, Kopernika 21, 31-501 Krakow (Poland))" data-affiliation=" (Jagiellonian University, Medical College, 2nd Department of Surgery, Kopernika 21, 31-501 Krakow (Poland))" >Trybus, M.

    2017-01-01

    The present paper concerns the potential use of montmorillonite as a drug carrier and focusses on the intercalation of the studied clay with gentamicin (an aminoglycoside antibiotic) at various temperatures (20, 50 and 80 °C). The experiments were performed to identify the temperature required for the optimum intercalation of gentamicin into the interlayer of montmorillonite. The structural and microstructural properties of gentamicin and the potential for introducing it between smectite clay layers were investigated by means of X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopic techniques, and SEM with EDS analysis. Additionally, the in vitro drug release behaviour of the montmorillonite-gentamicin complex and its antibacterial activity against Escherichia coli (E. coli) bacteria was investigated. Based on these studies, the impact of temperature on the intercalation of the drug between layers of smectite was evaluated. It was found that an intercalation temperature of 50 °C resulted in the highest shift in the position of principle peak d (001) as measured by XRD, suggesting, that the greatest amount of gentamicin had been introduced into the interlayer space of montmorillonite at this temperature. Subsequently, the montmorillonite-gentamicin complex material obtained at 50 °C revealed the greatest capacity for killing E. coli bacteria during an in vitro test. - Highlights: • A novel montmorillonite-gentamicin hybrid materials was prepared as potential drug carrier. • Optimal conditions for the intercalation of gentamicin into the interlayer space of montmorillonite were tested. • The MMT-G complex material obtained at 50 °C revealed the greatest capacity for killing E. coli during the inhibitory zone test. • Modulating drug delivery was monitored and confirmed in in vitro drug release study.

  6. Characterisation, in vitro release study, and antibacterial activity of montmorillonite-gentamicin complex material

    Energy Technology Data Exchange (ETDEWEB)

    Rapacz-Kmita, A., E-mail: kmita@agh.edu.pl [AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Krakow (Poland); Bućko, M.M.; Stodolak-Zych, E. [AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Krakow (Poland); Mikołajczyk, M. [The University Hospital in Krakow, Division of Microbiology, Kopernika 19, 31-501 Krakow (Poland); Dudek, P. [AGH University of Science and Technology, Faculty of Mechanical Engineering and Robotics, Mickiewicza 30, 30-059 Krakow (Poland); Trybus, M. [Jagiellonian University, Medical College, 2" n" d Department of Surgery, Kopernika 21, 31-501 Krakow (Poland)

    2017-01-01

    The present paper concerns the potential use of montmorillonite as a drug carrier and focusses on the intercalation of the studied clay with gentamicin (an aminoglycoside antibiotic) at various temperatures (20, 50 and 80 °C). The experiments were performed to identify the temperature required for the optimum intercalation of gentamicin into the interlayer of montmorillonite. The structural and microstructural properties of gentamicin and the potential for introducing it between smectite clay layers were investigated by means of X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopic techniques, and SEM with EDS analysis. Additionally, the in vitro drug release behaviour of the montmorillonite-gentamicin complex and its antibacterial activity against Escherichia coli (E. coli) bacteria was investigated. Based on these studies, the impact of temperature on the intercalation of the drug between layers of smectite was evaluated. It was found that an intercalation temperature of 50 °C resulted in the highest shift in the position of principle peak d{sub (001)} as measured by XRD, suggesting, that the greatest amount of gentamicin had been introduced into the interlayer space of montmorillonite at this temperature. Subsequently, the montmorillonite-gentamicin complex material obtained at 50 °C revealed the greatest capacity for killing E. coli bacteria during an in vitro test. - Highlights: • A novel montmorillonite-gentamicin hybrid materials was prepared as potential drug carrier. • Optimal conditions for the intercalation of gentamicin into the interlayer space of montmorillonite were tested. • The MMT-G complex material obtained at 50 °C revealed the greatest capacity for killing E. coli during the inhibitory zone test. • Modulating drug delivery was monitored and confirmed in in vitro drug release study.

  7. Potential Impact of Atmospheric Releases at Russian Far East Nuclear Submarine Complexes

    Energy Technology Data Exchange (ETDEWEB)

    Parker, F.; Mahura, A.; Compton, K.; Brown, K.; Takano, M.; Novikov, V.; Soerensen, J. H.; Baklanov, A.

    2003-02-25

    An ''Assessment of the Impact of Russian Nuclear Fleet Operations on Far Eastern Coastal Regions'' is being performed as part of the Radiation Safety of the Biosphere Project (RAD) of the International Institute for Applied Systems Analysis (IIASA) of Laxenburg, Austria. To the best of our knowledge, this is the first comprehensive unclassified analysis of the potential impact of accidents at the Russian Far East nuclear submarine sites near Vladivostok and Petropavlovsk. We have defined the situation there based upon available information and studies commissioned by RAD in collaboration with Russian research institutes including Russian Research Center-''Kurchatov Institute'', Institute of Northern Environmental Problems and Lazurit Central Design Bureau. Further, in our original work, some in collaboration with the staff of the Danish Meteorological Institute (DMI) and members of the Japan Atomic Energy Research Institute, we have calculated the nuclide trajectories from these sites in the atmospheric boundary layer, less than 1.5 kilometers high, and determined their probability of crossing any of the nearby countries as well as Asiatic Russia. We have further determined the concentrations in each of these crossings as well as the total, dry and wet depositions of nuclides on these areas. Finally, we have calculated the doses to the Japanese Island population from typical winter airflow patterns (those most likely to cross the Islands in the minimum times), strong north winds, weak north winds and cyclonic winds for conditions similar to the Chazhma Bay criticality accident (fresh fuel) and for a criticality accident for the same type of reactor with fuel being withdrawn (spent fuel). The maximum individual committed dosages were less than 2 x 10-7 and 2 x 10-3 mSv, respectively. The long-term external doses by radionuclides deposited on the ground and the internal doses by consumption of foods were not evaluated as it is

  8. Pea Border Cell Maturation and Release Involve Complex Cell Wall Structural Dynamics.

    Science.gov (United States)

    Mravec, Jozef; Guo, Xiaoyuan; Hansen, Aleksander Riise; Schückel, Julia; Kračun, Stjepan Krešimir; Mikkelsen, Maria Dalgaard; Mouille, Grégory; Johansen, Ida Elisabeth; Ulvskov, Peter; Domozych, David S; Willats, William George Tycho

    2017-06-01

    The adhesion of plant cells is vital for support and protection of the plant body and is maintained by a variety of molecular associations between cell wall components. In some specialized cases, though, plant cells are programmed to detach, and root cap-derived border cells are examples of this. Border cells (in some species known as border-like cells) provide an expendable barrier between roots and the environment. Their maturation and release is an important but poorly characterized cell separation event. To gain a deeper insight into the complex cellular dynamics underlying this process, we undertook a systematic, detailed analysis of pea ( Pisum sativum ) root tip cell walls. Our study included immunocarbohydrate microarray profiling, monosaccharide composition determination, Fourier-transformed infrared microspectroscopy, quantitative reverse transcription-PCR of cell wall biosynthetic genes, analysis of hydrolytic activities, transmission electron microscopy, and immunolocalization of cell wall components. Using this integrated glycobiology approach, we identified multiple novel modes of cell wall structural and compositional rearrangement during root cap growth and the release of border cells. Our findings provide a new level of detail about border cell maturation and enable us to develop a model of the separation process. We propose that loss of adhesion by the dissolution of homogalacturonan in the middle lamellae is augmented by an active biophysical process of cell curvature driven by the polarized distribution of xyloglucan and extensin epitopes. © 2017 American Society of Plant Biologists. All Rights Reserved.

  9. Pea Border Cell Maturation and Release Involve Complex Cell Wall Structural Dynamics1[OPEN

    Science.gov (United States)

    2017-01-01

    The adhesion of plant cells is vital for support and protection of the plant body and is maintained by a variety of molecular associations between cell wall components. In some specialized cases, though, plant cells are programmed to detach, and root cap-derived border cells are examples of this. Border cells (in some species known as border-like cells) provide an expendable barrier between roots and the environment. Their maturation and release is an important but poorly characterized cell separation event. To gain a deeper insight into the complex cellular dynamics underlying this process, we undertook a systematic, detailed analysis of pea (Pisum sativum) root tip cell walls. Our study included immunocarbohydrate microarray profiling, monosaccharide composition determination, Fourier-transformed infrared microspectroscopy, quantitative reverse transcription-PCR of cell wall biosynthetic genes, analysis of hydrolytic activities, transmission electron microscopy, and immunolocalization of cell wall components. Using this integrated glycobiology approach, we identified multiple novel modes of cell wall structural and compositional rearrangement during root cap growth and the release of border cells. Our findings provide a new level of detail about border cell maturation and enable us to develop a model of the separation process. We propose that loss of adhesion by the dissolution of homogalacturonan in the middle lamellae is augmented by an active biophysical process of cell curvature driven by the polarized distribution of xyloglucan and extensin epitopes. PMID:28400496

  10. Drug Release Kinetics and Front Movement in Matrix Tablets Containing Diltiazem or Metoprolol/λ-Carrageenan Complexes

    Directory of Open Access Journals (Sweden)

    Ruggero Bettini

    2014-01-01

    Full Text Available In this work we investigated the moving boundaries and the associated drug release kinetics in matrix tablets prepared with two complexes between λ-carrageenan and two soluble model drugs, namely, diltiazem HCl and metoprolol tartrate aiming at clarifying the role played by drug/polymer interaction on the water uptake, swelling, drug dissolution, and drug release performance of the matrix. The two studied complexes released the drug with different mechanism indicating two different drug/polymer interaction strengths. The comparison between the drug release behaviour of the complexes and the relevant physical mixtures indicates that diltiazem gave rise to a less soluble and more stable complex with carrageenan than metoprolol. The less stable metoprolol complex afforded an erodible matrix, whereas the stronger interaction between diltiazem and carrageenan resulted in a poorly soluble, slowly dissolving matrix. It was concluded that the different stability of the studied complexes affords two distinct drug delivery systems: in the case of MTP, the dissociation of the complex, as a consequence of the interaction with water, affords a classical soluble matrix type delivery system; in the case of DTZ, the dissolving/diffusing species is the complex itself because of the very strong interaction between the drug and the polymer.

  11. High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal

    Directory of Open Access Journals (Sweden)

    Kilbride Seán M

    2011-07-01

    Full Text Available Abstract Background The activities of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2 and complex IV (cytochrome c oxidase EC 1.9.3.1 are reduced by 30-70% in Huntington's disease and Alzheimer's disease, respectively, and are associated with excitotoxic cell death in these disorders. In this study, we investigated the control that complexes III and complex IV exert on glutamate release from the isolated nerve terminal. Results Inhibition of complex III activity by 60-90% was necessary for a major increase in the rate of Ca2+-independent glutamate release to occur from isolated nerve terminals (synaptosomes depolarized with 4-aminopyridine or KCl. Similarly, an 85-90% inhibition of complex IV activity was required before a major increase in the rate of Ca2+-independent glutamate release from depolarized synaptosomes was observed. Inhibition of complex III and IV activities by ~ 60% and above was required before rates of glutamate efflux from polarized synaptosomes were increased. Conclusions These results suggest that nerve terminal mitochondria possess high reserves of complex III and IV activity and that high inhibition thresholds must be reached before excess glutamate is released from the nerve terminal. The implications of the results in the context of the relationship between electron transport chain enzyme deficiencies and excitotoxicity in neurodegenerative disorders are discussed.

  12. High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal

    LENUS (Irish Health Repository)

    Kilbride, Sean M

    2011-07-26

    Abstract Background The activities of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2) and complex IV (cytochrome c oxidase EC 1.9.3.1) are reduced by 30-70% in Huntington\\'s disease and Alzheimer\\'s disease, respectively, and are associated with excitotoxic cell death in these disorders. In this study, we investigated the control that complexes III and complex IV exert on glutamate release from the isolated nerve terminal. Results Inhibition of complex III activity by 60-90% was necessary for a major increase in the rate of Ca2+-independent glutamate release to occur from isolated nerve terminals (synaptosomes) depolarized with 4-aminopyridine or KCl. Similarly, an 85-90% inhibition of complex IV activity was required before a major increase in the rate of Ca2+-independent glutamate release from depolarized synaptosomes was observed. Inhibition of complex III and IV activities by ~ 60% and above was required before rates of glutamate efflux from polarized synaptosomes were increased. Conclusions These results suggest that nerve terminal mitochondria possess high reserves of complex III and IV activity and that high inhibition thresholds must be reached before excess glutamate is released from the nerve terminal. The implications of the results in the context of the relationship between electron transport chain enzyme deficiencies and excitotoxicity in neurodegenerative disorders are discussed.

  13. Protein Complexation and pH Dependent Release Using Boronic Acid Containing PEG-Polypeptide Copolymers.

    Science.gov (United States)

    Negri, Graciela E; Deming, Timothy J

    2017-01-01

    New poly(L-lysine)-b-poly(ethylene glycol) copolypeptides have been prepared, where the side-chain amine groups of lysine residues are modified to contain ortho-amine substituted phenylboronic acid, i.e., Wulff-type phenylboronic acid (WBA), groups to improve their pH responsive, carbohydrate binding properties. These block copolymers form nanoscale complexes with glycosylated proteins that are stable at physiological pH, yet dissociate and release the glycoproteins under acidic conditions, similar to those found in endosomal and lysosomal compartments within cells. These results suggest that WBA modified polypeptide copolymers are promising for further development as degradable carriers for intracellular protein delivery. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Pea border cell maturation and release involve complex cell wall structural dynamics

    DEFF Research Database (Denmark)

    Mravec, Jozef; Guo, Xiaoyuan; Hansen, Aleksander Riise

    2017-01-01

    The adhesion of plant cells is vital for support and protection of the plant body and is maintained by a variety of molecular associations between cell wall components. In some specialized cases though, plant cells are programmed to detach and root cap-derived border cells are examples of this....... Border cells (in some species known as border-like cells) provide an expendable barrier between roots and the environment. Their maturation and release is an important but poorly characterized cell separation event. To gain a deeper insight into the complex cellular dynamics underlying this process, we...... undertook a systematic, detailed analysis of pea (Pisum sativum) root tip cell walls. Our study included immuno-carbohydrate microarray profiling, monosaccharide composition determination, Fourier-transformed infrared microspectroscopy (FT-IR), quantitative RT-PCR of cell wall biosynthetic genes, analysis...

  15. Statistics of meteorological data at Tokai Research Establishment in JAERI

    International Nuclear Information System (INIS)

    Sekita, Tsutomu; Tachibana, Haruo; Matsuura, Kenichi; Yamaguchi, Takenori

    2003-12-01

    The meteorological observation data at Tokai site were analyzed statistically based on a 'Guideline of meteorological statistics for the safety analysis of nuclear power reactor' (Nuclear Safety Commission on January 28, 1982; revised on March 29, 2001). This report shows the meteorological analysis of wind direction, wind velocity and atmospheric stability etc. to assess the public dose around the Tokai site caused by the released gaseous radioactivity. The statistical period of meteorological data is every 5 years from 1981 to 1995. (author)

  16. Polymer-surfactant complexes for microencapsulation of vitamin E and its release.

    Science.gov (United States)

    Sharipova, A A; Aidarova, S B; Grigoriev, D; Mutalieva, B; Madibekova, G; Tleuova, A; Miller, R

    2016-01-01

    Microencapsulation of vitamin E directly from oil-in-water (o/w) emulsions was carried out by means of a novel practically relevant approach. For the first time, a preformed polyelectrolyte-surfactant complex (sodium polystyrene sulfonate/dodecyl trimethyl ammonium bromide) was simultaneously used as an electrosteric emulsion stabilizer and as a charged precursor for the following build up of microcapsules. Subsequently, a layer-by-layer technique was applied to emulsions leading to the formation of core-shell microcapsules with oily cores and polyelectrolyte shells. The effect of the complexes on the process of emulsion formation and on the stability and characteristics of the resulting emulsions was investigated by measurements of dynamic and equilibrium interfacial tension, size distribution (DLS) and interfacial charge (zeta-potential). The resulting microcapsules were characterized by confocal laser scanning microscopy (CLSM), Cryo-SEM, size distribution and zeta-potential measurements on each stage of the shell assembly. The release kinetics of vitamin E was monitored during the consecutive steps of the encapsulation procedure using UV-vis spectroscopy and showed the progressive enhancement of sustainability. The developed approach may be promising for the practical use in the cosmetic and food industry. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. RNA-Seq reveals complex genetic response to deepwater horizon oil release in Fundulus grandis

    Directory of Open Access Journals (Sweden)

    Garcia Tzintzuni I

    2012-09-01

    Full Text Available Abstract Background The release of oil resulting from the blowout of the Deepwater Horizon (DH drilling platform was one of the largest in history discharging more than 189 million gallons of oil and subject to widespread application of oil dispersants. This event impacted a wide range of ecological habitats with a complex mix of pollutants whose biological impact is still not yet fully understood. To better understand the effects on a vertebrate genome, we studied gene expression in the salt marsh minnow Fundulus grandis, which is local to the northern coast of the Gulf of Mexico and is a sister species of the ecotoxicological model Fundulus heteroclitus. To assess genomic changes, we quantified mRNA expression using high throughput sequencing technologies (RNA-Seq in F. grandis populations in the marshes and estuaries impacted by DH oil release. This application of RNA-Seq to a non-model, wild, and ecologically significant organism is an important evaluation of the technology to quickly assess similar events in the future. Results Our de novo assembly of RNA-Seq data produced a large set of sequences which included many duplicates and fragments. In many cases several of these could be associated with a common reference sequence using blast to query a reference database. This reduced the set of significant genes to 1,070 down-regulated and 1,251 up-regulated genes. These genes indicate a broad and complex genomic response to DH oil exposure including the expected AHR-mediated response and CYP genes. In addition a response to hypoxic conditions and an immune response are also indicated. Several genes in the choriogenin family were down-regulated in the exposed group; a response that is consistent with AH exposure. These analyses are in agreement with oligonucleotide-based microarray analyses, and describe only a subset of significant genes with aberrant regulation in the exposed set. Conclusion RNA-Seq may be successfully applied to feral and

  18. Meteorological perspective on intermediate range atmospheric dispersion

    International Nuclear Information System (INIS)

    Van der Hoven, I.

    1981-01-01

    The intermediate range of atmospheric transport and diffusion is defined as those dispersion processes which take place at downwind distances of 10 to 100 kilometers from pollutant sources. Meteorologists often define this range as the mesoscale. It is the range of distances where certain environmental assessments are of concern such as the determination of significant deterioration of visibility, the effect of effluent releases from tall stacks, and the effect of pollutant sources in rural settings upon the more distant urban centers. Atmospheric diffusion theory is based on steady state conditions and spatial homogeniety. Techniques must be developed to measure the inhomogenieties, models must be devised to account for the complexities, and a data base consisting of appropriate measured meteorological parameters concurrent with tracer gas concentrations should be collected

  19. Monitoring of meteorology and air quality at influence area of COMPERJ (Rio de Janeiro Petrochemical Complex); Monitoramento meteorologico e da qualidade do ar na regiao de influencia do COMPERJ (Complexo Petroquimico do Rio de Janeiro)

    Energy Technology Data Exchange (ETDEWEB)

    Albuquerque, Edler Lins de; Villa, Felipe de Santana; Lyra, Diogenes Ganghis Pimentel de [CETREL-LUMINA Solucoes Ambientais, Salvador, BA (Brazil); Secron, Marcelo; Iorio, Patricia Freire; Mendes, Marcos Faistauer [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2008-07-01

    Rio de Janeiro Petrochemical Complex (COMPERJ) will be installed in the north region of Itaborai city. The start of COMPERJ operations is foreseen to 2012. Because of the intensification of industrialization and urbanization processes, the implantation of COMPERJ will bring environmental modifications for Itaborai city and neighbors areas. Thus, meteorological and air quality monitoring was initiated in February of 2007 with the intention of carrying out a characterization of air pollution in this area, before COMPERJ operations. In this work are presented the results found in campaigns performed of February of 2007 until April of 2008. The meteorological monitoring disclosed that the meteorological parameters have varied enough throughout the months, but these are representative of a global behavior of the studied area. Monitoring of air quality has shown that atmospheric levels of monitored pollutants has been generally below of Brazilian air quality standards. This fact corroborates the basic aspect of the present study: identification of the concentrations 'background' in the studied area. Throughout the period of monitoring, the primary air quality standard for ozone has been reached. Observations of meteorological parameters indicate that this fact is associated to the emissions originated from Sao Goncalo, Niteroi and Rio de Janeiro cities. (author)

  20. Sustained release of antibiotic complexed by multivalent ion: in vitro and in vivo study for the treatment of peritonitis.

    Science.gov (United States)

    Na, Seung Yeon; Oh, Se Heang; Kim, Tae Ho; Yoon, Jin A; Lee, In Soo; Lee, Jin Ho

    2014-12-10

    The main aims of this study are (i) the development of an antibiotic complexed with multivalent ion, which can allow sustained release of the antibiotic without any additional matrix or difficult process and (ii) the feasibility study of the ion-complexed antibiotic as a therapeutic technique for peritonitis treatment. An ion-complexed antibiotic is prepared by simple mixing of two aqueous solutions containing an ionized (water-soluble) drug (tetracycline) and a multivalent counter ionic compound. The ion-complexed antibiotic shows a continuous release of the antibiotic up to 21 days, and thus prolonged anti-bacterial effect by gradual ionic exchange between the multivalent ions in the complex and same-charged monovalent ions in surrounding medium. From the in vivo animal study using a cecum perforated peritonitis mouse model, the ion-complexed antibiotic group shows sufficient anti-bacterial effect and thus effectively treat the peritonitis because of the extermination of the contaminated enteric bacteria in the peritoneum during wound healing of injury cecum (by the sustained release of antibiotic from the ion complex). These results suggest that the ion-complexed antibiotic system may be promising for the effective treatment of the peritonitis caused by frequent gastrointestinal defect in clinical fields. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Automated emergency meteorological response system

    International Nuclear Information System (INIS)

    Pepper, D.W.

    1980-01-01

    A sophisticated emergency response system was developed to aid in the evaluation of accidental releases of hazardous materials from the Savannah River Plant to the environment. A minicomputer system collects and archives data from both onsite meteorological towers and the National Weather Service. In the event of an accidental release, the computer rapidly calculates the trajectory and dispersion of pollutants in the atmosphere. Computer codes have been developed which provide a graphic display of predicted concentration profiles downwind from the source, as functions of time and distance

  2. Comparative In Vitro Controlled Release Studies on the Chronobiotic Hormone Melatonin from Cyclodextrins-Containing Matrices and Cyclodextrin: Melatonin Complexes.

    Science.gov (United States)

    Vlachou, Marilena; Papamichael, Marianna; Siamidi, Angeliki; Fragouli, Irene; Afroudakis, Pandelis A; Kompogennitaki, Rodanthi; Dotsikas, Yannis

    2017-07-28

    A series of hydrophilic matrix tablets was prepared and tested with respect to their ability to release the hormone melatonin in a controlled manner, in order to alleviate sleep onset and sleep maintenance dysfunctions. Besides the active ingredient, the tablets were comprised of combinations of the following: HPMC K 15M, low viscosity sodium alginate, microcrystalline cellulose (Avicel PH 102), magnesium stearate, and the cyclodextrins, α-CD, β-CD, γ-CD, HP-β-CD, sulfated β-CD, HP-α-CD and HP-γ-CD, and MLT (guest):CD (host) complexes of the above cyclodextrins, in 1:1 ratio. The controlled release studies were conducted in two aqueous dissolution media at pH 1.2 and 7.4. The stoichiometry of the formed complexes was examined by applying the continuous variation method (Job plot), while the stability constants were calculated by monitoring the spectrophotometric properties of free and CD-encapsulated melatonin (UV-Vis). Host-guest interactions were studied by Nuclear Magnetic Resonance (NMR) spectroscopy. The dissolution data suggest that melatonin is released faster from the MLT:CD complexes than from the rest matrix systems. This enhancement in the dissolution rate and the % release of melatonin from the complexes is due to the increased solubility of the MLT:CD complexes.

  3. Complex Enzyme-Assisted Extraction Releases Antioxidative Phenolic Compositions from Guava Leaves.

    Science.gov (United States)

    Wang, Lu; Wu, Yanan; Liu, Yan; Wu, Zhenqiang

    2017-09-30

    Phenolics in food and fruit tree leaves exist in free, soluble-conjugate, and insoluble-bound forms. In this study, in order to enhance the bioavailability of insoluble-bound phenolics from guava leaves (GL), the ability of enzyme-assisted extraction in improving the release of insoluble-bound phenolics was investigated. Compared to untreated GL, single xylanase-assisted extraction did not change the composition and yield of soluble phenolics, whereas single cellulase or β -glucosidase-assisted extraction significantly enhanced the soluble phenolics content of PGL. However, complex enzyme-assisted extraction (CEAE) greatly improved the soluble phenolics content, flavonoids content, ABTS, DPPH, and FRAP by 103.2%, 81.6%, 104.4%, 126.5%, and 90.3%, respectively. Interestingly, after CEAE, a major proportion of phenolics existed in the soluble form, and rarely in the insoluble-bound form. Especially, the contents of quercetin and kaempferol with higher bio-activity were enhanced by 3.5- and 2.2-fold, respectively. More importantly, total soluble phenolics extracts of GL following CEAE exhibited the highest antioxidant activity and protective effect against supercoiled DNA damage. This enzyme-assisted extraction technology can be useful for extracting biochemical components from plant matrix, and has good potential for use in the food and pharmaceutical industries.

  4. Complex Enzyme-Assisted Extraction Releases Antioxidative Phenolic Compositions from Guava Leaves

    Directory of Open Access Journals (Sweden)

    Lu Wang

    2017-09-01

    Full Text Available Phenolics in food and fruit tree leaves exist in free, soluble-conjugate, and insoluble-bound forms. In this study, in order to enhance the bioavailability of insoluble-bound phenolics from guava leaves (GL, the ability of enzyme-assisted extraction in improving the release of insoluble-bound phenolics was investigated. Compared to untreated GL, single xylanase-assisted extraction did not change the composition and yield of soluble phenolics, whereas single cellulase or β-glucosidase-assisted extraction significantly enhanced the soluble phenolics content of PGL. However, complex enzyme-assisted extraction (CEAE greatly improved the soluble phenolics content, flavonoids content, ABTS, DPPH, and FRAP by 103.2%, 81.6%, 104.4%, 126.5%, and 90.3%, respectively. Interestingly, after CEAE, a major proportion of phenolics existed in the soluble form, and rarely in the insoluble-bound form. Especially, the contents of quercetin and kaempferol with higher bio-activity were enhanced by 3.5- and 2.2-fold, respectively. More importantly, total soluble phenolics extracts of GL following CEAE exhibited the highest antioxidant activity and protective effect against supercoiled DNA damage. This enzyme-assisted extraction technology can be useful for extracting biochemical components from plant matrix, and has good potential for use in the food and pharmaceutical industries.

  5. Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.

    Science.gov (United States)

    Cloutier, Nathalie; Allaeys, Isabelle; Marcoux, Genevieve; Machlus, Kellie R; Mailhot, Benoit; Zufferey, Anne; Levesque, Tania; Becker, Yann; Tessandier, Nicolas; Melki, Imene; Zhi, Huiying; Poirier, Guy; Rondina, Matthew T; Italiano, Joseph E; Flamand, Louis; McKenzie, Steven E; Cote, Francine; Nieswandt, Bernhard; Khan, Waliul I; Flick, Matthew J; Newman, Peter J; Lacroix, Steve; Fortin, Paul R; Boilard, Eric

    2018-02-13

    There is a growing appreciation for the contribution of platelets to immunity; however, our knowledge mostly relies on platelet functions associated with vascular injury and the prevention of bleeding. Circulating immune complexes (ICs) contribute to both chronic and acute inflammation in a multitude of clinical conditions. Herein, we scrutinized platelet responses to systemic ICs in the absence of tissue and endothelial wall injury. Platelet activation by circulating ICs through a mechanism requiring expression of platelet Fcγ receptor IIA resulted in the induction of systemic shock. IC-driven shock was dependent on release of serotonin from platelet-dense granules secondary to platelet outside-in signaling by αIIbβ3 and its ligand fibrinogen. While activated platelets sequestered in the lungs and leaky vasculature of the blood-brain barrier, platelets also sequestered in the absence of shock in mice lacking peripheral serotonin. Unexpectedly, platelets returned to the blood circulation with emptied granules and were thereby ineffective at promoting subsequent systemic shock, although they still underwent sequestration. We propose that in response to circulating ICs, platelets are a crucial mediator of the inflammatory response highly relevant to sepsis, viremia, and anaphylaxis. In addition, platelets recirculate after degranulation and sequestration, demonstrating that in adaptive immunity implicating antibody responses, activated platelets are longer lived than anticipated and may explain platelet count fluctuations in IC-driven diseases.

  6. BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements.

    Science.gov (United States)

    Bhagwat, Anand S; Roe, Jae-Seok; Mok, Beverly Y L; Hohmann, Anja F; Shi, Junwei; Vakoc, Christopher R

    2016-04-19

    The bromodomain and extraterminal (BET) protein BRD4 can physically interact with the Mediator complex, but the relevance of this association to the therapeutic effects of BET inhibitors in cancer is unclear. Here, we show that BET inhibition causes a rapid release of Mediator from a subset of cis-regulatory elements in the genome of acute myeloid leukemia (AML) cells. These sites of Mediator eviction were highly correlated with transcriptional suppression of neighboring genes, which are enriched for targets of the transcription factor MYB and for functions related to leukemogenesis. A shRNA screen of Mediator in AML cells identified the MED12, MED13, MED23, and MED24 subunits as performing a similar regulatory function to BRD4 in this context, including a shared role in sustaining a block in myeloid maturation. These findings suggest that the interaction between BRD4 and Mediator has functional importance for gene-specific transcriptional activation and for AML maintenance. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  7. Lloyd Berkner: Catalyst for Meteorology's Fabulous Fifties

    Science.gov (United States)

    Lewis, J. M.

    2002-05-01

    In the long sweep of meteorological history - from Aristotle's Meteorologica to the threshold of the third millennium - the 1950s will surely be recognized as a defining decade. The contributions of many individuals were responsible for the combination of vision and institution building that marked this decade and set the stage for explosive development during the subsequent forty years. In the minds of many individuals who were active during those early years, however, one name stands out as a prime mover par excellence: Lloyd Viel Berkner. On May 1, 1957, Berkner addressed the National Press Club. The address was entitled, "Horizons of Meteorology". It reveals Berkner's insights into meteorology from his position as Chairman of the Committee on Meteorology of the National Academy of Sciences, soon to release the path-breaking report, Research and Education in Meteorology (1958). The address also reflects the viewpoint of an individual deeply involved in the International Geophysical Year (IGY). It is an important footnote to meteorological history. We welcome this opportunity to profile Berkner and to discuss "Horizons of Meteorology" in light of meteorology's state-of-affairs in the 1950s and the possible relevance to Berkner's ideas to contemporary issues.

  8. Complexity of the influence of gangliosides on histamine release from human basophils and rat mast cells

    DEFF Research Database (Denmark)

    Jensen, C; Svendsen, U G; Thastrup, Ole

    1987-01-01

    The influence of exogenous addition of gangliosides on histamine release from human basophils and rat mast cells was examined in vitro. Gangliosides dose-dependently inhibited histamine release, and this inhibition was dependent on the ganglioside sialic acid content, since GT1b, having 3 sialic...... was reflected in the sensitivity of the cells to extracellular calcium, since inhibition of the release could be counteracted by increasing the extracellular concentration of calcium....

  9. XOQDOQ, Meteorological Evaluation of Atmospheric Nuclear Power Plant Effluents

    International Nuclear Information System (INIS)

    Sagendorf, J.F.; Goll, J.T.; Sandusky, W.F.; Eyberger, L.R.

    1990-01-01

    1 - Description of program or function: XOQDOQ was designed for meteorological evaluation of continuous and anticipated intermittent releases from commercial nuclear power reactors. It calculates annual relative effluent concentrations and average relative deposition values at locations specified by the user and at various standard radial distances and segments for downwind sectors. It also calculates these values at the specified locations for anticipated intermittent (e.g. containment or purge) releases, which occur during routine operation. The program computes an effective plume height that accounts for physical release height, aerodynamic down-wash, plume rise, and terrain features. The user may optionally select additional plume dispersion due to building wakes, plume depletion via dry deposition, and plume radioactive decay, or specify adjustments to represent non-straight line trajectories (recirculation or stagnation). 2 - Method of solution: XOQDOQ is based on the principle that diffusion of material released to the atmosphere can be described by a Gaussian distribution within the plume with transport described by a straight-line trajectory. The horizontal and vertical dispersion coefficients are empirically determined, largely from observations at or near ground level. The program implements the assumptions outlined in Section C of NRC Regulatory Guide 1.111. Long-term average values of relative effluent concentration are calculated by assuming a long-term continuous release with effluent distributed evenly across a 22-1/2 degree sector. 3 - Restrictions on the complexity of the problem - Maxima of: 30 receptor locations/receptor type, 14 wind-speed classes, 10 distances of site-specific recirculation correction factors, 8 receptor types, 7 atmospheric stability categories, 5 separate release points. XOQDOQ cannot handle multiple emission sources or plume depletion via wet deposition, or evaluate the meteorological aspects of the consequences of

  10. Metal ion-assisted self-assembly of complexes for controlled and sustained release of minocycline for biomedical applications

    International Nuclear Information System (INIS)

    Zhang, Zhiling; Wang, Zhicheng; Nong, Jia; Nix, Camilla A; Zhong, Yinghui; Ji, Hai-Feng

    2015-01-01

    This study reports the development of novel drug delivery complexes self-assembled by divalent metal ion-assisted coacervation for controlled and sustained release of a hydrophilic small drug molecule minocycline hydrochloride (MH). MH is a multifaceted agent that has demonstrated therapeutic effects in infection, inflammation, tumor, as well as cardiovascular, renal, and neurological disorders due to its anti-microbial, anti-inflammatory, and cytoprotective properties. However, the inability to translate the high doses used in experimental animals to tolerable doses in human patients limits its clinical application. Localized delivery can potentially expose the diseased tissue to high concentrations of MH that systemic delivery cannot achieve, while minimizing the side effects from systemic exposure. The strong metal ion binding-assisted interaction enabled high drug entrapment and loading efficiency, and stable long term release for more than 71 d. Released MH demonstrated potent anti-biofilm, anti-inflammatory, and neuroprotective activities. Furthermore, MH release from the complexes is pH-sensitive as the chelation between minocycline and metal ions decreases with pH, allowing ‘smart’ drug release in response to the severity of pathology-induced tissue acidosis. This novel metal ion binding-mediated drug delivery mechanism can potentially be applied to other drugs that have high binding affinity for metal ions and may lead to the development of new delivery systems for a variety of drugs. (paper)

  11. Effective Anti-miRNA Oligonucleotides Show High Releasing Rate of MicroRNA from RNA-Induced Silencing Complex.

    Science.gov (United States)

    Ariyoshi, Jumpei; Matsuyama, Yohei; Kobori, Akio; Murakami, Akira; Sugiyama, Hiroshi; Yamayoshi, Asako

    2017-10-01

    MicroRNAs (miRNAs) regulate gene expression by forming RNA-induced silencing complexes (RISCs) and have been considered as promising therapeutic targets. MiRNA is an essential component of RISC for the modulation of gene expression. Therefore, the release of miRNA from RISC is considered as an effective method for the inhibition of miRNA functions. In our previous study, we reported that anti-miRNA oligonucleotides (AMOs), which are composed of the 2'-O-methyl (2'-OMe) RNA, could induce the release of miRNA from RISC. However, the mechanisms underlying the miRNA-releasing effects of chemically modified AMOs, which are conventionally used as anti-cancer drugs, are still unclear. In this study, we investigated the relationship between the miRNA releasing rate from RISC and the inhibitory effect on RISC activity (IC 50 ) using conventional chemically modified AMOs. We demonstrated that the miRNA-releasing effects of AMOs are directly proportional to the IC 50 values, and AMOs, which have an ability to promote the release of miRNA from RISC, can effectively inhibit RISC activity in living cells.

  12. Half-Sandwich Ru(II and Os(II Bathophenanthroline Complexes Containing a Releasable Dichloroacetato Ligand

    Directory of Open Access Journals (Sweden)

    Pavel Štarha

    2018-02-01

    Full Text Available We report on the preparation and thorough characterization of cytotoxic half-sandwich complexes [Ru(η6-pcym(bphen(dca]PF6 (Ru-dca and [Os(η6-pcym(bphen(dca]PF6 (Os-dca containing dichloroacetate(1– (dca as the releasable O-donor ligand bearing its own cytotoxicity; pcym = 1-methyl-4-(propan-2-ylbenzene (p-cymene, bphen = 4,7-diphenyl-1,10-phenanthroline (bathophenanthroline. Complexes Ru-dca and Os-dca hydrolyzed in the water-containing media, which led to the dca ligand release (supported by 1H NMR and electrospray ionization mass spectra. Mass spectrometry studies revealed that complexes Ru-dca and Os-dca do not interact covalently with the model proteins cytochrome c and lysozyme. Both complexes exhibited slightly higher in vitro cytotoxicity (IC50 = 3.5 μM for Ru-dca, and 2.6 μM for Os-dca against the A2780 human ovarian carcinoma cells than cisplatin (IC50 = 5.9 μM, while their toxicity on the healthy human hepatocytes was found to be IC50 = 19.1 μM for Ru-dca and IC50 = 19.7 μM for Os-dca. Despite comparable cytotoxicity of complexes Ru-dca and Os-dca, both the complexes modified the cell cycle, mitochondrial membrane potential, and mitochondrial cytochrome c release by a different way, as revealed by flow cytometry experiments. The obtained results point out the different mechanisms of action between the complexes.

  13. Lectures in Micro Meteorology

    DEFF Research Database (Denmark)

    Larsen, Søren Ejling

    This report contains the notes from my lectures on Micro scale meteorology at the Geophysics Department of the Niels Bohr Institute of Copenhagen University. In the period 1993-2012, I was responsible for this course at the University. At the start of the course, I decided that the text books...... available in meteorology at that time did not include enough of the special flavor of micro meteorology that characterized the work of the meteorology group at Risø (presently of the Institute of wind energy of the Danish Technical University). This work was focused on Boundary layer flows and turbulence...

  14. Complex comprised of dextran magnetite and conjugated cisplatin exhibiting selective hyperthermic and controlled-release potential

    Directory of Open Access Journals (Sweden)

    Akinaga Sonoda

    2010-07-01

    Full Text Available Akinaga Sonoda1, Norihisa Nitta1, Ayumi Nitta-Seko1, Shinich Ohta1, Shigeyuki Takamatsu2, Yoshio Ikehata3, Isamu Nagano3, Jun-ichiro Jo4, Yasuhiko Tabata4, Masashi Takahashi1, Osamu Matsui3, Kiyoshi Murata11Department of Radiology, Shiga University of Medical Science, Setatsukinowa-cho, Otsu, Shiga, 520-2192, Japan; 2Department of Radiology, Graduate School of Medical Science, Kanazawa University, Takara-machi 13-1, Kanazawa Ishikawa, 920-8641, Japan; 3Department of Natural Science and Technology, Graduate School of Engineering, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan; 4Department of Biomaterials, Institute for Frontier Medical Sciences, Kyoto University, Shogoin kawara-machi 53, Sakyo-ku 606-8507, Kyoto, JapanAbstract: We developed a dextran-magnetite conjugated cisplatin (DM-Cis complex for use in thermal ablation and as a chemotherapeutic drug. To produce DM-Cis we reacted Cis with 1 mL DM (56 mg/mL iron. The temperature rise of DM-Cis was measured in vitro and in vivo under a portable induction-heating (IH device. Platinum desorption from DM-Cis over 24 hours was measured in bovine serum. In in vivo accumulation and magnet and exothermic experiments we used four rat groups. In group 1 we delivered DM-Cis intraperitoneally (ip and placed magnets subcutaneously (sc. In group 2 we injected saline (ip and placed magnets (sc. In group 3 we injected DM-Cis (ip and placed a sc incision (sham. The control (group 4 received an ip injection of saline. Rectus abdominis muscle tissue was stained with hematoxylin-eosin and iron-stained tissue areas (µm2 were calculated. The maximum platinum concentration in DM-Cis was approximately 105.6 µg/mL. Over 24 hours, 33.48% of platinum from DM-Cis was released. There was a significant difference (P < 0.05 in the iron-stained area between group 1 and the other groups. The temperature in muscle tissue registered a maximum of 56°C after about 4 min. DM-Cis may represent a

  15. Tetrapeptide-coumarin conjugate 3D networks based on hydrogen-bonded charge transfer complexes: gel formation and dye release.

    Science.gov (United States)

    Guo, Zongxia; Gong, Ruiying; Jiang, Yi; Wan, Xiaobo

    2015-08-14

    Oligopeptide-based derivatives are important synthons for bio-based functional materials. In this article, a Gly-(L-Val)-Gly-(L-Val)-coumarin (GVGV-Cou) conjugate was synthesized, which forms 3D networks in ethanol. The gel nanostructures were characterized by UV-vis spectroscopy, FT-IR spectroscopy, X-ray diffraction (XRD), SEM and TEM. It is suggested that the formation of charge transfer (CT) complexes between the coumarin moieties is the main driving force for the gel formation. The capability of the gel to encapsulate and release dyes was explored. Both Congo Red (CR) and Methylene Blue (MB) can be trapped in the CT gel matrix and released over time. The present gel might be used as a functional soft material for guest encapsulation and release.

  16. Drug Release from ß-Cyclodextrin Complexes and Drug Transfer into Model Membranes Studied by Affinity Capillary Electrophoresis.

    Science.gov (United States)

    Darwish, Kinda A; Mrestani, Yahya; Rüttinger, Hans-Hermann; Neubert, Reinhard H H

    2016-05-01

    Is to characterize the drug release from the ß-cyclodextrin (ß-CD) cavity and the drug transfer into model membranes by affinity capillary electrophoresis. Phospholipid liposomes with and without cholesterol were used to mimic the natural biological membrane. The interaction of cationic and anionic drugs with ß-CD and the interaction of the drugs with liposomes were detected separately by measuring the drug mobility in ß-CD containing buffer and liposome containing buffer; respectively. Moreover, the kinetics of drug release from ß-CD and its transfer into liposomes with or without cholesterol was studied by investigation of changes in the migration behaviours of the drugs in samples, contained drug, ß-CD and liposome, at 1:1:1 molar ratio at different time intervals; zero time, 30 min, 1, 2, 4, 6, 8, 10 and 24 h. Lipophilic drugs such as propranolol and ibuprofen were chosen for this study, because they form complexes with ß-CD. The mobility of the both drug liposome mixtures changed with time to a final state. For samples of liposomal membranes with cholesterol the final state was faster reached than without cholesterol. The study confirmed that the drug release from the CD cavity and its transfer into the model membrane was more enhanced by the competitive displacement of the drug from the ß-CD cavity by cholesterol, the membrane component. The ACE method here developed can be used to optimize the drug release from CD complexes and the drug transfer into model membranes.

  17. Preparation, physicochemical characterization and release behavior of the inclusion complex of trans-anethole and β-cyclodextrin.

    Science.gov (United States)

    Zhang, Wenwen; Li, Xinying; Yu, Taocheng; Yuan, Lun; Rao, Gang; Li, Defu; Mu, Changdao

    2015-08-01

    Trans-anethole (AT) has a variety of antimicrobial properties and is widely used as food functional ingredient. However, the applications of AT are limited due to its low water solubility, strong odor and low physicochemical stability. Therefore, the aim of this work was to encapsulate AT with β-cyclodextrin (β-CD) for obtaining inclusion complex by co-precipitation method. The measurements effectively confirmed the formation of inclusion complex between AT and β-CD. The results showed that the inclusion complex presented new solid crystalline phases and was more thermally stable than the physical mixture and β-CD. The phase solubility study showed that the aqueous solubility of AT was increased by being included in β-CD. The calculated stability constant of inclusion complex was 1195M -1 , indicating the strong interaction between AT and β-CD. Furthermore, the release study suggested that β-CD provided the protection for AT against evaporation. The release behavior of AT from the inclusion complex was controlled. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Fire and forest meteorology

    Science.gov (United States)

    SA Ferguson; T.J. Brown; M. Flannigan

    2005-01-01

    The American Meteorological Society symposia series on Fire and Forest Meteorology provides biennial forums for atmospheric and fire scientists to introduce and discuss the latest and most relevant research on weather, climate and fire. This special issue highlights significant work that was presented at the Fifth Symposium in Orlando, Florida during 16-20 November...

  19. METRODOS: Meteorological preprocessor chain

    DEFF Research Database (Denmark)

    Astrup, P.; Mikkelsen, T.; Deme, S.

    2001-01-01

    The METRODOS meteorological preprocessor chain combines measured tower data and coarse grid numerical weather prediction (NWP) data with local scale flow models and similarity scaling to give high resolution approximations of the meteorological situation. Based on available wind velocity and dire...

  20. Meteorological satellite systems

    CERN Document Server

    Tan, Su-Yin

    2014-01-01

    Meteorological Satellite Systems” is a primer on weather satellites and their Earth applications. This book reviews historic developments and recent technological advancements in GEO and polar orbiting meteorological satellites. It explores the evolution of these remote sensing technologies and their capabilities to monitor short- and long-term changes in weather patterns in response to climate change. Satellites developed by various countries, such as U.S. meteorological satellites, EUMETSAT, and Russian, Chinese, Japanese and Indian satellite platforms are reviewed. This book also discusses international efforts to coordinate meteorological remote sensing data collection and sharing. This title provides a ready and quick reference for information about meteorological satellites. It serves as a useful tool for a broad audience that includes students, academics, private consultants, engineers, scientists, and teachers.

  1. Wind Power Meteorology

    DEFF Research Database (Denmark)

    Lundtang Petersen, Erik; Mortensen, Niels Gylling; Landberg, Lars

    Wind power meteorology has evolved as an applied science, firmly founded on boundary-layer meteorology, but with strong links to climatology and geography. It concerns itself with three main areas: siting of wind turbines, regional wind resource assessment, and short-term prediction of the wind...... resource. The history, status and perspectives of wind power meteorology are presented, with emphasis on physical considerations and on its practical application. Following a global view of the wind resource, the elements of boundary layer meteorology which are most important for wind energy are reviewed......: wind profiles and shear, turbulence and gust, and extreme winds. The data used in wind power meteorology stem mainly from three sources: onsite wind measurements, the synoptic networks, and the re-analysis projects. Wind climate analysis, wind resource estimation and siting further require a detailed...

  2. Unraveling complexities of velocity dependent retention and release parameters for E. coli in saturated porous media

    Science.gov (United States)

    Escherichia coli transport and release experiments were conducted to investigate the pore-water velocity (v) dependency of the sticking efficiency (a), the fraction of the solid surface area that contributed to retention (Sf), the percentage of injected cells that were irreversibly retained (Mirr), ...

  3. Controlled release of astaxanthin from nanoporous silicified-phospholipids assembled boron nitride complex for cosmetic applications

    Science.gov (United States)

    Lee, Hye Sun; Sung, Dae Kyung; Kim, Sung Hyun; Choi, Won Il; Hwang, Ee Tag; Choi, Doo Jin; Chang, Jeong Ho

    2017-12-01

    Nanoporous silicified-phospholipids assembled boron nitride (nSPLs@BN) powder was prepared and demonstrated for use in controlled release of anti-oxidant astaxanthin (AX) as a cosmetic application. The nanoporous silicified phospholipids (nSPLs) were obtained by the silicification with tetraethyl orthosilicate (TEOS) of the hydrophilic region of phospholipid bilayers. This process involved the co-assembly of chemically active phospholipid bilayers within the porous silica matrix. In addition, nSPLs@BN was characterized using several analytical techniques and tested to assess their efficiency as drug delivery systems. We calculated the maximum release amounts as a function of time and various pH. The release rate of AX from the nSPLs@BN for the initial 24 h was 10.7 μmol/(h mg) at pH 7.4. Furthermore, we determined the antioxidant activity (KD) for the released AX with DPPH (1,1-diphenyl-2-picryl-hydrazyl) radical and the result was 34.6%.

  4. Silver release and antimicrobial properties of PMMA films doped with silver ions, nano-particles and complexes

    Energy Technology Data Exchange (ETDEWEB)

    Lyutakov, O., E-mail: lyutakoo@vscht.cz [Department of Solid State Engineering, Institute of Chemical Technology, Prague (Czech Republic); Goncharova, I. [Department of Analytical Chemistry, Institute of Chemical Technology, Prague (Czech Republic); Rimpelova, S. [Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague (Czech Republic); Kolarova, K.; Svanda, J.; Svorcik, V. [Department of Solid State Engineering, Institute of Chemical Technology, Prague (Czech Republic)

    2015-04-01

    Materials prepared on the base of bioactive silver compounds have become more and more popular due to low microbial resistance to silver. In the present work, the efficiency of polymethylmethacrylate (PMMA) thin films doped with silver ions, nanoparticles and silver–imidazole polymer complex was studied by a combination of AAS, XPS and AFM techniques. The biological activities of the proposed materials were discussed in view of the rate of silver releasing from the polymer matrix. Concentrations of Ag active form were estimated by its ability to interact with L-cysteine using electronic circular dichroism spectroscopy. Rates of the released silver were compared with the biological activity in dependence on the form of embedded silver. Antimicrobial properties of doped polymer films were studied using two bacterial strains: Staphylococcus epidermidis and Escherichia coli. It was found that PMMA films doped with Ag{sup +} had greater activity than those doped with nanoparticles and silver–imidazole polymeric complexes. However, the antimicrobial efficiency of Ag{sup +} doped films was only short-term. Contrary, the antimicrobial activity of silver–imidazole/PMMA films increased in time of sample soaking. - Highlights: • PMMA thin films doped with silver ions, nanoparticles (AgNPs) and silver–imidazole helical complexes (AgIm) were studied. • Silver release from doped polymer films and its biological activity were estimated. • Antimicrobial properties of doped polymer films were also studied. • Ag ions doped films showed the strongest antimicrobial activity, which quickly disappeared. • AgIm and AgNPs doped films showed more stable antimicrobial properties. • AgIm complexes conserve their structure after addition into polymer and after leaching.

  5. Silver release and antimicrobial properties of PMMA films doped with silver ions, nano-particles and complexes

    International Nuclear Information System (INIS)

    Lyutakov, O.; Goncharova, I.; Rimpelova, S.; Kolarova, K.; Svanda, J.; Svorcik, V.

    2015-01-01

    Materials prepared on the base of bioactive silver compounds have become more and more popular due to low microbial resistance to silver. In the present work, the efficiency of polymethylmethacrylate (PMMA) thin films doped with silver ions, nanoparticles and silver–imidazole polymer complex was studied by a combination of AAS, XPS and AFM techniques. The biological activities of the proposed materials were discussed in view of the rate of silver releasing from the polymer matrix. Concentrations of Ag active form were estimated by its ability to interact with L-cysteine using electronic circular dichroism spectroscopy. Rates of the released silver were compared with the biological activity in dependence on the form of embedded silver. Antimicrobial properties of doped polymer films were studied using two bacterial strains: Staphylococcus epidermidis and Escherichia coli. It was found that PMMA films doped with Ag + had greater activity than those doped with nanoparticles and silver–imidazole polymeric complexes. However, the antimicrobial efficiency of Ag + doped films was only short-term. Contrary, the antimicrobial activity of silver–imidazole/PMMA films increased in time of sample soaking. - Highlights: • PMMA thin films doped with silver ions, nanoparticles (AgNPs) and silver–imidazole helical complexes (AgIm) were studied. • Silver release from doped polymer films and its biological activity were estimated. • Antimicrobial properties of doped polymer films were also studied. • Ag ions doped films showed the strongest antimicrobial activity, which quickly disappeared. • AgIm and AgNPs doped films showed more stable antimicrobial properties. • AgIm complexes conserve their structure after addition into polymer and after leaching

  6. Fast-Dissolving, Prolonged Release, and Antibacterial Cyclodextrin/Limonene-Inclusion Complex Nanofibrous Webs via Polymer-Free Electrospinning.

    Science.gov (United States)

    Aytac, Zeynep; Yildiz, Zehra Irem; Kayaci-Senirmak, Fatma; San Keskin, Nalan Oya; Kusku, Semran Ipek; Durgun, Engin; Tekinay, Turgay; Uyar, Tamer

    2016-10-05

    We have proposed a new strategy for preparing free-standing nanofibrous webs from an inclusion complex (IC) of a well-known flavor/fragrance compound (limonene) with three modified cyclodextrins (HPβCD, MβCD, and HPγCD) via electrospinning (CD/limonene-IC-NFs) without using a polymeric matrix. The experimental and computational modeling studies proved that the stoichiometry of the complexes was 1:1 for CD/limonene systems. MβCD/limonene-IC-NF released much more limonene at 37, 50, and 75 °C than HPβCD/limonene-IC-NF and HPγCD/limonene-IC-NF because of the greater amount of preserved limonene. Moreover, MβCD/limonene-IC-NF has released only 25% (w/w) of its limonene, whereas HPβCD/limonene-IC-NF and HPγCD/limonene-IC-NF released 51 and 88% (w/w) of their limonene in 100 days, respectively. CD/limonene-IC-NFs exhibited high antibacterial activity against E. coli and S. aureus. The water solubility of limonene increased significantly and CD/limonene-IC-NFs were dissolved in water in a few seconds. In brief, CD/limonene-IC-NFs with fast-dissolving character enhanced the thermal stability and prolonged the shelf life along with antibacterial properties could be quite applicable in food and oral care applications.

  7. Kinetic, spectroscopic and chemical modification study of iron release from transferrin; iron(III) complexation to adenosine triphosphate

    International Nuclear Information System (INIS)

    Thompson, C.P.

    1985-01-01

    Amino acids other than those that serve as ligands have been found to influence the chemical properties of transferrin iron. The catalytic ability of pyrophosphate to mediate transferrin iron release to a terminal acceptor is largely quenched by modification non-liganded histine groups on the protein. The first order rate constants of iron release for several partially histidine modified protein samples were measured. A statistical method was employed to establish that one non-liganded histidine per metal binding domain was responsible for the reduction in rate constant. These results imply that the iron mediated chelator, pyrophosphate, binds directly to a histidine residue on the protein during the iron release process. EPR spectroscopic results are consistent with this interpretation. Kinetic and amino acid sequence studies of ovotransferrin and lactoferrin, in addition to human serum transferrin, have allowed the tentative assignment of His-207 in the N-terminal domain and His-535 in the C-terminal domain as the groups responsible for the reduction in rate of iron release. The above concepts have been extended to lysine modified transferrin. Complexation of iron(II) to adenosine triphosphate (ATP) was also studied to gain insight into the nature of iron-ATP species present at physiological pH. 31 P NMR spectra are observed when ATP is presented in large excess

  8. US Marine Meteorological Journals

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This series consists of volumes entitled 'Meteorological Journal' (a regulation Navy-issue publication) which were to be completed by masters of merchant vessels...

  9. Wave Meteorology and Soaring

    Science.gov (United States)

    Wiley, Scott

    2008-01-01

    This viewgraph document reviews some mountain wave turbulence and operational hazards while soaring. Maps, photographs, and satellite images of the meteorological phenomena are included. Additionally, photographs of aircraft that sustained mountain wave damage are provided.

  10. Climate and meteorology

    International Nuclear Information System (INIS)

    Hoitink, D.J.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the significant activities conducted in 1994 to monitor the meteorology and climatology of the site. Meteorological measurements are taken to support Hanford Site emergency preparedness and response, Hanford Site operations, and atmospheric dispersion calculations. Climatological data are collected to help plan weather-dependent activities and are used as a resource to assess the environmental effects of Hanford Site operations

  11. Climate and meteorology

    Energy Technology Data Exchange (ETDEWEB)

    Hoitink, D.J.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the significant activities conducted in 1994 to monitor the meteorology and climatology of the site. Meteorological measurements are taken to support Hanford Site emergency preparedness and response, Hanford Site operations, and atmospheric dispersion calculations. Climatological data are collected to help plan weather-dependent activities and are used as a resource to assess the environmental effects of Hanford Site operations.

  12. Implantable biodegradable sponges: effect of interpolymer complex formation of chitosan with gelatin on the release behavior of tramadol hydrochloride.

    Science.gov (United States)

    Foda, Nagwa H; El-laithy, Hanan M; Tadros, Mina I

    2007-01-01

    The effect of interpolymer complex formation between positively charged chitosan and negatively charged gelatin (Type B) on the release behavior of tramadol hydrochloride from biodegradable chitosan-gelatin sponges was studied. Mixed sponges were prepared by freeze-drying the cross-linked homogenous stable foams produced from chitosan and gelatin solutions where gelatin acts as a foam builder. Generation of stable foams was optimized where concentration, pH of gelatin solution, temperature, speed and duration of whipping process, and, chitosan-gelatin ratio drastically affect the properties and the stability of the produced foams. The prepared sponges were evaluated for their morphology, drug content, and microstructure using scanning electron microscopy, mechanical properties, uptake capacity, drug release profile, and their pharmacodynamic activity in terms of the analgesic effect after implantation in Wistar rats. It was revealed that whipping 7% (w/w) gelatin solution, of pH 5.5, for 15 min at 25 degrees C with a stirring speed of 1000 rpm was the optimum conditions for stable gelatin foam generation. Moreover, homogenous, uniform chitosan-gelatin foam with small air bubbles were produced by mixing 2.5% w/w chitosan solution with 7% w/w gelatin solution in 1:5 ratio. Indeed, polyionic complexation between chitosan and gelatin overcame the drawbacks of chitosan sponge mechanical properties where, pliable, soft, and compressible sponge with high fluid uptake capacity was produced at 25 degrees C and 65% relative humidity without any added plasticizer. Drug release studies showed a successful retardation of the incorporated drug where the t50% values of the dissolution profiles were 0.55, 3.03, and 4.73 hr for cross-linked gelatin, un-cross-linked chitosan-gelatin, and cross-linked chitosan-gelatin sponges, respectively. All the release experiments followed Higuchi's diffusion mechanism over 12 hr. The achieved drug prolongation was a result of a combined effect

  13. [An experimental study on a slow-release complex with rifampicin-polylactic-co-glycolic acid-calcium 
phosphate cement].

    Science.gov (United States)

    Wu, Jianhuang; Ding, Zhou; Lei, Qing; Li, Miao; Liang, Yan; Lu, Tao

    2016-09-28

    To prepare the slow-release complex with rifampicin (RFP)-polylactic-co-glycolic acid (PLGA)-calcium phosphate cement (CPC) (RFP-PLGA-CPC complex), and to study its physical and chemical properties and drug release properties in vitro.
 The emulsification-solvent evaporation method was adopted to prepare rifampicin polylactic acid-glycolic acid (RFP-PLGA) slow-release microspheres, which were divided into 3 groups: a calcium phosphate bone cement group (CPC group), a CPC embedded with RFP group (RFP-CPC group), and a PLGA slow-release microspheres carrying RFP and the self-curing CPC group (RFP- PLGA-CPC complex group). The solidification time and porosity of materials were determined. The drug release experiments in vitro were carried out to observe the compressive strength, the change of section morphology before and after drug release. 
 The CPC group showed the shortest solidification time, while the RFP-PLGA-CPC complex group had the longest one. There was statistical difference in the porosity between the CPC group and the RFP-CPC group (Pbehavior of the complex, which was in accordance with zero order kinetics equation F=0.168×t.
 The porosity of RFP-PLGA-CPC complex is significantly higher than that of CPC, and it can keep slow release of the effective anti-tuberculosis drugs and maintain a certain mechanical strength for a long time.

  14. Meteorology and lidar data from the URAHFREP field trials

    DEFF Research Database (Denmark)

    Ott, Søren; Ejsing Jørgensen, Hans

    2002-01-01

    to the HF release. The instrumentation included various types of HF sensors, thermocouple arrays, a fully instrumented release rig, a passive smokemachine, a meteorological mast and a lidar backscatter system. This report deals exclusively with the meteorological data and the lidar data. The trials cover...... a range meteorological conditions. These include neutral conditions with relatively highwindspeed and low humidity as well as unstable conditions with low windspeed and high humidity, the most favorable conditions for lift-off to occur. The lidar was used to scan vertical cross-plume slices 100 meter...

  15. Release of polyanions from polyelectrolyte complexes by selective degradation of the polycation

    Czech Academy of Sciences Publication Activity Database

    Etrych, Tomáš; Boustta, M.; Leclercq, L.; Vert, M.

    2006-01-01

    Roč. 21, č. 2 (2006), s. 89-105 ISSN 0883-9115 Institutional research plan: CEZ:AV0Z40500505 Keywords : polyelectrolyte complex * enzymatic degradation * hydrolytic degradation Subject RIV: CD - Macromolecular Chemistry Impact factor: 0.925, year: 2006

  16. Robotic Transversus Abdominis Release (TAR: is it possible to offer minimally invasive surgery for abdominal wall complex defects?

    Directory of Open Access Journals (Sweden)

    MARIA VITÓRIA FRANÇA DO AMARAL

    Full Text Available ABSTRACT We describe the preliminary national experience and the early results of the use of robotic surgery to perform the posterior separation of abdominal wall components by the Transversus Abdominis Release (TAR technique for the correction of complex defects of the abdominal wall. We performed the procedures between 04/2/2015 and 06/15/2015 and the follow-up time was up to six months, with a minimum of two months. The mean surgical time was five hours and 40 minutes. Two patients required laparoscopic re-intervention, since one developed hernia by peritoneal migration of the mesh and one had mesh extrusion. The procedure proved to be technically feasible, with a still long surgical time. Considering the potential advantages of robotic surgery and those related to TAR and the results obtained when these two techniques are associated, we conclude that they seem to be a good option for the correction of complex abdominal wall defects.

  17. Meteorology Products - Naval Oceanography Portal

    Science.gov (United States)

    section Advanced Search... Sections Home Time Earth Orientation Astronomy Meteorology Oceanography Ice You are here: Home › FNMOC › Meteorology Products FNMOC Logo FNMOC Navigation Meteorology Products Oceanography Products Tropical Applications Climatology and Archived Data Info Meteorology Products Global

  18. Automated data system for emergency meteorological response

    International Nuclear Information System (INIS)

    Kern, C.D.

    1975-01-01

    The Savannah River Plant (SRP) releases small amounts of radioactive nuclides to the atmosphere as a consequence of the production of radioisotopes. The potential for larger accidental releases to the atmosphere also exists, although the probability for most accidents is low. To provide for emergency meteorological response to accidental releases and to conduct research on the transport and diffusion of radioactive nuclides in the routine releases, a series of high-quality meteorological sensors have been located on towers in and about SRP. These towers are equipped with instrumentation to detect and record temperature and wind turbulence. Signals from the meterological sensors are brought by land-line to the SRL Weather Center-Analysis Laboratory (WC-AL). At the WC-AL, a Weather Information and Display (WIND) system has been installed. The WIND system consists of a minicomputer with graphical displays in the WC-AL and also in the emergency operating center (EOC) of SRP. In addition, data are available to the system from standard weat []er teletype services, which provide both routine surface weather observations and routine upper air wind and temperature observations for the southeastern United States. Should there be an accidental release to the atmosphere, available recorded data and computer codes would allow the calculation and display of the location, time, and downwind concentration of the atmospheric release. These data are made available to decision makers in near real-time to permit rapid decisive action to limit the consequences of such accidental releases. (auth)

  19. Polyelectrolyte Complex Based Interfacial Drug Delivery System with Controlled Loading and Improved Release Performance for Bone Therapeutics

    Directory of Open Access Journals (Sweden)

    David Vehlow

    2016-03-01

    Full Text Available An improved interfacial drug delivery system (DDS based on polyelectrolyte complex (PEC coatings with controlled drug loading and improved release performance was elaborated. The cationic homopolypeptide poly(l-lysine (PLL was complexed with a mixture of two cellulose sulfates (CS of low and high degree of substitution, so that the CS and PLL solution have around equal molar charged units. As drugs the antibiotic rifampicin (RIF and the bisphosphonate risedronate (RIS were integrated. As an important advantage over previous PEC systems this one can be centrifuged, the supernatant discarded, the dense pellet phase (coacervate separated, and again redispersed in fresh water phase. This behavior has three benefits: (i Access to the loading capacity of the drug, since the concentration of the free drug can be measured by spectroscopy; (ii lower initial burst and higher residual amount of drug due to removal of unbound drug and (iii complete adhesive stability due to the removal of polyelectrolytes (PEL excess component. It was found that the pH value and ionic strength strongly affected drug content and release of RIS and RIF. At the clinically relevant implant material (Ti40Nb similar PEC adhesive and drug release properties compared to the model substrate were found. Unloaded PEC coatings at Ti40Nb showed a similar number and morphology of above cultivated human mesenchymal stem cells (hMSC compared to uncoated Ti40Nb and resulted in considerable production of bone mineral. RIS loaded PEC coatings showed similar effects after 24 h but resulted in reduced number and unhealthy appearance of hMSC after 48 h due to cell toxicity of RIS.

  20. Effect of pullulan nanoparticle surface charges on HSA complexation and drug release behavior of HSA-bound nanoparticles.

    Directory of Open Access Journals (Sweden)

    Xiaojun Tao

    Full Text Available Nanoparticle (NP compositions such as hydrophobicity and surface charge are vital to determine the presence and amount of human serum albumin (HSA binding. The HSA binding influences drug release, biocompatibility, biodistribution, and intercellular trafficking of nanoparticles (NPs. Here, we prepared 2 kinds of nanomaterials to investigate HSA binding and evaluated drug release of HSA-bound NPs. Polysaccharides (pullulan carboxyethylated to provide ionic derivatives were then conjugated to cholesterol groups to obtain cholesterol-modified carboxyethyl pullulan (CHCP. Cholesterol-modified pullulan (CHP conjugate was synthesized with a similar degree of substitution of cholesterol moiety to CHCP. CHCP formed self-aggregated NPs in aqueous solution with a spherical structure and zeta potential of -19.9 ± 0.23 mV, in contrast to -1.21 ± 0.12 mV of CHP NPs. NPs could quench albumin fluorescence intensity with maximum emission intensity gradually decreasing up to a plateau at 9 to 12 h. Binding constants were 1.12 × 10(5 M(-1 and 0.70 × 10(5 M(-1 to CHP and CHCP, respectively, as determined by Stern-Volmer analysis. The complexation between HSA and NPs was a gradual process driven by hydrophobic force and inhibited by NP surface charge and shell-core structure. HSA conformation was altered by NPs with reduction of α-helical content, depending on interaction time and particle surface charges. These NPs could represent a sustained release carrier for mitoxantrone in vitro, and the bound HSA assisted in enhancing sustained drug release.

  1. Suppression of the release of arsenic from arsenopyrite by carrier-microencapsulation using Ti-catechol complex.

    Science.gov (United States)

    Park, Ilhwan; Tabelin, Carlito Baltazar; Magaribuchi, Kagehiro; Seno, Kensuke; Ito, Mayumi; Hiroyoshi, Naoki

    2018-02-15

    Arsenopyrite is the most common arsenic-bearing sulfide mineral in nature, and its weathering contributes to acid mine drainage (AMD) formation and the release of toxic arsenic (As). To mitigate this problem, carrier-microencapsulation (CME) using titanium (Ti)-catechol complex (i.e., Ti-based CME) was investigated to passivate arsenopyrite by forming a protective coating. Ti 4+ ion dissolved in sulfuric acid and catechol were used to successfully synthesize Ti(IV) tris-catecholate complex, [Ti(Cat) 3 ] 2- , which was stable in the pH range of 5-12. Electrochemical studies on the redox properties of this complex indicate that its oxidative decomposition was a one-step, irreversible process. The leaching of As from arsenopyrite was suppressed by CME treatment using the synthesized Ti-catechol complex. Scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDX) and diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) indicate that this suppression was primarily due to the formation of an anatase (β-TiO 2 )-containing coating. Based on these results, a detailed 4-step mechanism to explain the decomposition of [Ti(Cat) 3 ] 2- and formation of TiO 2 coating in Ti-based CME is proposed: (1) adsorption, (2) partial oxidation-intermediate formation, (3) non electrochemical dissociation, and (4) hydrolysis-precipitation. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. In-situ complex with by-product HCl and release chloride ions to dissolve aramid.

    Science.gov (United States)

    Dai, Yu; Cheng, Zheng; Yuan, Yihao; Meng, Chenbo; Qin, Jiaqiang; Liu, Xiangyang

    2018-06-20

    Because of the strong hydrogen-bond interaction among macromolecular chains, addition of chloride salts is generally needed to offer Cl- ions for dissolution of aromatic polyamides. In this paper, poly-(benzimidazole-terephthalamide) which complexed with by-product HCl during polymerization (PABI-HCl) was prepared and imidazole compound as cosolvent was added into dimethylacetamide (DMAc) to dissolve PABI-HCl. Due to stronger affinity to protons, imidazole compound could in-situ complex with HCl of PABI-HCl and form imidazolium hydrochloride. Then imidazolium hydrochloride would ionize and produce much free Cl- ions which acted as stronger hydrogen-bond acceptor to disrupt interaction among macromolecular chains. As a result, solubility of PABI-HCl in DMAc was improved significantly in existence of small amount of imidazole compound. Moreover, DMAc-imidazole mixture was utlized for synthesis of different kinds of aramids and no precipitation was observed with progress of the reaction. So the mixture was suitable to be utlized as solvent for polymerization of aramid. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Combination of binaural and harmonic masking release effects in the detection of a single component in complex tones.

    Science.gov (United States)

    Klein-Hennig, Martin; Dietz, Mathias; Hohmann, Volker

    2018-03-01

    Both harmonic and binaural signal properties are relevant for auditory processing. To investigate how these cues combine in the auditory system, detection thresholds for an 800-Hz tone masked by a diotic (i.e., identical between the ears) harmonic complex tone were measured in six normal-hearing subjects. The target tone was presented either diotically or with an interaural phase difference (IPD) of 180° and in either harmonic or "mistuned" relationship to the diotic masker. Three different maskers were used, a resolved and an unresolved complex tone (fundamental frequency: 160 and 40 Hz) with four components below and above the target frequency and a broadband unresolved complex tone with 12 additional components. The target IPD provided release from masking in most masker conditions, whereas mistuning led to a significant release from masking only in the diotic conditions with the resolved and the narrowband unresolved maskers. A significant effect of mistuning was neither found in the diotic condition with the wideband unresolved masker nor in any of the dichotic conditions. An auditory model with a single analysis frequency band and different binaural processing schemes was employed to predict the data of the unresolved masker conditions. Sensitivity to modulation cues was achieved by including an auditory-motivated modulation filter in the processing pathway. The predictions of the diotic data were in line with the experimental results and literature data in the narrowband condition, but not in the broadband condition, suggesting that across-frequency processing is involved in processing modulation information. The experimental and model results in the dichotic conditions show that the binaural processor cannot exploit modulation information in binaurally unmasked conditions. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Jesuits' Contribution to Meteorology.

    Science.gov (United States)

    Udías, Agustín

    1996-10-01

    Starting in the middle of the nineteenth century, as part of their scientific tradition, Jesuits founded a considerable number of meteorological observatories throughout the world. In many countries, Jesuits established and maintained the first meteorological stations during the period from 1860 to 1950. The Jesuits' most important contribution to atmospheric science was their pioneer work related to the study and forecast of tropical hurricanes. That research was carried out at observatories of Belén (Cuba), Manila (Philippines), and Zikawei (China). B. Viñes, M. Decheyrens, J. Aigué, and C.E. Deppermann stood out in this movement.

  5. Meteorology in site operations

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    During the site selection and design phases of a plant, meteorological assistance must be based on past records, usually accumulated at stations not actually on the site. These preliminary atadvices will be averages and extremes that might be expected. After a location has been chosen and work has begun, current and forecast weather conditions become of immediate concern. On-site meteorological observations and forecasts have many applications to the operating program of an atomic energy site. Requirements may range from observations of the daily minimum temperatures to forecasts of radiation dosages from airborne clouds

  6. Applied Meteorology Unit (AMU)

    Science.gov (United States)

    Bauman, William; Crawford, Winifred; Barrett, Joe; Watson, Leela; Wheeler, Mark

    2010-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the first quarter of Fiscal Year 2010 (October - December 2009). A detailed project schedule is included in the Appendix. Included tasks are: (1) Peak Wind Tool for User Launch Commit Criteria (LCC), (2) Objective Lightning Probability Tool, Phase III, (3) Peak Wind Tool for General Forecasting, Phase II, (4) Upgrade Summer Severe Weather Tool in Meteorological Interactive Data Display System (MIDDS), (5) Advanced Regional Prediction System (ARPS) Data Analysis System (ADAS) Update and Maintainability, (5) Verify 12-km resolution North American Model (MesoNAM) Performance, and (5) Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) Graphical User Interface.

  7. Health risk evaluation in a population exposed to chemical releases from a petrochemical complex in Thailand.

    Science.gov (United States)

    Kampeerawipakorn, Ormrat; Navasumrit, Panida; Settachan, Daam; Promvijit, Jeerawan; Hunsonti, Potchanee; Parnlob, Varabhorn; Nakngam, Netnapa; Choonvisase, Suppachai; Chotikapukana, Passaornrawan; Chanchaeamsai, Samroeng; Ruchirawat, Mathuros

    2017-01-01

    Emissions from petrochemical industries may contain toxic and carcinogenic compounds that can pose health risk to human populations. The scenario may be worse in developing countries where management of such exposure-health problems is typically not well-implemented and the public may not be well-informed about such health risk. In Thailand, increasing incidences of respiratory diseases and cancers have been reported for the population around a major petrochemical complex, the Map Ta Phut Industrial Estate (MTPIE). This study aimed to systematically investigate an exposure-health risk among these populations. One-hundred and twelve healthy residents living nearby MTPIE and 50 controls located approximately 40km from MTPIE were recruited. Both external and internal exposure doses to benzene and 1,3-butadiene, known to be associated with the types of cancer that are of concern, were measured because they represent exposure to industrial and/or traffic-related emissions. Health risk was assessed using the biomarkers of early biological effects for cancer and inflammatory responses, as well as biomarkers of exposure for benzene and 1,3-butadiene. The exposure levels of benzene and 1,3-butadiene were similar for both the exposed and control groups. This was confirmed by a non-significant difference in the levels of specific urinary metabolites for benzene (trans,trans-muconic acid, t,t-MA) and 1,3-butadiene (monohydroxy-butyl mercapturic acid, MHBMA). Levels of 8-hydroxydeoxyguanosine (8-OHdG) and DNA strand breaks between the two groups were not statistically significantly different. However, functional biomarkers, interleukin-8 (IL-8) expression was significantly higher (pindustrial complex could be causing these functional abnormalities. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Computer Exercises in Meteorology.

    Science.gov (United States)

    Trapasso, L. Michael; Conner, Glen; Stallins, Keith

    Beginning with Western Kentucky University's (Bowling Green) fall 1999 semester, exercises required for the geography and meteorology course used computers for learning. This course enrolls about 250 students per year, most of whom choose it to fulfill a general education requirement. Of the 185 geography majors, it is required for those who…

  9. Comparison of generation 3 polyamidoamine dendrimer and generation 4 polypropylenimine dendrimer on drug loading, complex structure, release behavior, and cytotoxicity

    Science.gov (United States)

    Shao, Naimin; Su, Yunzhang; Hu, Jingjing; Zhang, Jiahai; Zhang, Hongfeng; Cheng, Yiyun

    2011-01-01

    Background Polyamidoamine (PAMAM) and polypropylenimine (PPI) dendrimers are the commercially available and most widely used dendrimers in pharmaceutical sciences and biomedical engineering. In the present study, the loading and release behaviors of generation 3 PAMAM and generation 4 PPI dendrimers with the same amount of surface amine groups (32 per dendrimer) were compared using phenylbutazone as a model drug. Methods The dendrimer-phenylbutazone complexes were characterized by 1H nuclear magnetic resonance and nuclear Overhauser effect techniques, and the cytotoxicity of each dendrimer was evaluated. Results Aqueous solubility results suggest that the generation 3 PAMAM dendrimer has a much higher loading ability towards phenylbutazone in comparison with the generation 4 PPI dendrimer at high phenylbutazone-dendrimer feeding ratios. Drug release was much slower from the generation 3 PAMAM matrix than from the generation 4 PPI dendrimer. In addition, the generation 3 PAMAM dendrimer is at least 50-fold less toxic than generation 4 PPI dendrimer on MCF-7 and A549 cell lines. Conclusion Although the nuclear Overhauser effect nuclear magnetic resonance results reveal that the generation 4 PPI dendrimer with a more hydrophobic interior encapsulates more phenylbutazone, the PPI dendrimer-phenylbutazone inclusion is not stable in aqueous solution, which poses a great challenge during drug development. PMID:22267921

  10. Background of the Military Aviation Meteorological Service

    Directory of Open Access Journals (Sweden)

    V.I. Zshumatiy

    2016-09-01

    Full Text Available The article is devoted to the birth of aviation and its meteorological service in the early twentieth century. The article details the military aviation meteorological services in Italy, France, Germany, Austria, the USA and Russia. Are described the problems, which arose with the takeoff and landings of flight vehicles with complex weather conditions. It is shown that the information about the actual and forthcoming weather is capable of reducing a quantity of failures of flight vehicles, of increasing safety of pilots and accuracy of the defeat of enemy, of planning the application of aviation.

  11. Surface Meteorology and Solar Energy

    Data.gov (United States)

    National Aeronautics and Space Administration — Surface Meteorology and Solar Energy data - over 200 satellite-derived meteorology and solar energy parameters, monthly averaged from 22 years of data, global solar...

  12. In silico, experimental, mechanistic model for extended-release felodipine disposition exhibiting complex absorption and a highly variable food interaction.

    Directory of Open Access Journals (Sweden)

    Sean H J Kim

    Full Text Available The objective of this study was to develop and explore new, in silico experimental methods for deciphering complex, highly variable absorption and food interaction pharmacokinetics observed for a modified-release drug product. Toward that aim, we constructed an executable software analog of study participants to whom product was administered orally. The analog is an object- and agent-oriented, discrete event system, which consists of grid spaces and event mechanisms that map abstractly to different physiological features and processes. Analog mechanisms were made sufficiently complicated to achieve prespecified similarity criteria. An equation-based gastrointestinal transit model with nonlinear mixed effects analysis provided a standard for comparison. Subject-specific parameterizations enabled each executed analog's plasma profile to mimic features of the corresponding six individual pairs of subject plasma profiles. All achieved prespecified, quantitative similarity criteria, and outperformed the gastrointestinal transit model estimations. We observed important subject-specific interactions within the simulation and mechanistic differences between the two models. We hypothesize that mechanisms, events, and their causes occurring during simulations had counterparts within the food interaction study: they are working, evolvable, concrete theories of dynamic interactions occurring within individual subjects. The approach presented provides new, experimental strategies for unraveling the mechanistic basis of complex pharmacological interactions and observed variability.

  13. Virtual Meteorological Center

    Directory of Open Access Journals (Sweden)

    Marius Brinzila

    2007-10-01

    Full Text Available A virtual meteorological center, computer based with Internet possibility transmission of the information is presented. Circumstance data is collected with logging field meteorological station. The station collects and automatically save data about the temperature in the air, relative humidity, pressure, wind speed and wind direction, rain gauge, solar radiation and air quality. Also can perform sensors test, analyze historical data and evaluate statistical information. The novelty of the system is that it can publish data over the Internet using LabVIEW Web Server capabilities and deliver a video signal to the School TV network. Also the system performs redundant measurement of temperature and humidity and was improved using new sensors and an original signal conditioning module.

  14. Meteorological instrumentation for nuclear facilities

    International Nuclear Information System (INIS)

    Costa, A.C.L. da.

    1983-01-01

    The main requirements of regulatory agencies, concerning the meteorological instrumentation needed for the licensing of nuclear facilities are discussed. A description is made of the operational principles of sensors for the various meteorological parameters and associated electronic systems. An analysis of the problems associated with grounding of a typical meteorological station is presented. (Author) [pt

  15. Meteorological instrumentation for nuclear installations

    International Nuclear Information System (INIS)

    Costa, A.C.L. da.

    1983-01-01

    The main requirements of regulatory agencies, concerning the meteorological instrumentation needed for the licensing of nuclear facilities are discussed. A description is made of the operational principles of sensors for the various meteorological parameters and associated electronic systems. Finally, it is presented an analysis of the problems associated with grounding of a typical meteorological station. (Author) [pt

  16. Pantex Plant meteorological monitoring program

    International Nuclear Information System (INIS)

    Snyder, S.F.

    1993-07-01

    The current meteorological monitoring program of the US Department of Energy's Pantex Plant, Amarillo, Texas, is described in detail. Instrumentation, meteorological data collection and management, and program management are reviewed. In addition, primary contacts are noted for instrumentation, calibration, data processing, and alternative databases. The quality assurance steps implemented during each portion of the meteorological monitoring program are also indicated

  17. Gold nanoparticles interacting with β-cyclodextrin-phenylethylamine inclusion complex: a ternary system for photothermal drug release.

    Science.gov (United States)

    Sierpe, Rodrigo; Lang, Erika; Jara, Paul; Guerrero, Ariel R; Chornik, Boris; Kogan, Marcelo J; Yutronic, Nicolás

    2015-07-22

    We report the synthesis of a 1:1 β-cyclodextrin-phenylethylamine (βCD-PhEA) inclusion complex (IC) and the adhesion of gold nanoparticles (AuNPs) onto microcrystals of this complex, which forms a ternary system. The formation of the IC was confirmed by powder X-ray diffraction and NMR analyses ((1)H and ROESY). The stability constant of the IC (760 M(-1)) was determined using the phase solubility method. The adhesion of AuNPs was obtained using the magnetron sputtering technique, and the presence of AuNPs was confirmed using UV-vis spectroscopy (surface plasmon resonance effect), which showed an absorbance at 533 nm. The powder X-ray diffractograms of βCD-PhEA were similar to those of the crystals decorated with AuNPs. A comparison of the one- and two-dimensional NMR spectra of the IC with and without AuNPs suggests partial displacement of the guest to the outside of the βCD due to attraction toward AuNPs, a characteristic tropism effect. The size, morphology, and distribution of the AuNPs were analyzed using TEM and SEM. The average size of the AuNPs was 14 nm. Changes in the IR and Raman spectra were attributed to the formation of the complex and to the specific interactions of this group with the AuNPs. Laser irradiation assays show that the ternary system βCD-PhEA-AuNPs in solution enables the release of the guest.

  18. Effect of harmonicity on the detection of a signal in a complex masker and on spatial release from masking.

    Directory of Open Access Journals (Sweden)

    Astrid Klinge

    Full Text Available The amount of masking of sounds from one source (signals by sounds from a competing source (maskers heavily depends on the sound characteristics of the masker and the signal and on their relative spatial location. Numerous studies investigated the ability to detect a signal in a speech or a noise masker or the effect of spatial separation of signal and masker on the amount of masking, but there is a lack of studies investigating the combined effects of many cues on the masking as is typical for natural listening situations. The current study using free-field listening systematically evaluates the combined effects of harmonicity and inharmonicity cues in multi-tone maskers and cues resulting from spatial separation of target signal and masker on the detection of a pure tone in a multi-tone or a noise masker. A linear binaural processing model was implemented to predict the masked thresholds in order to estimate whether the observed thresholds can be accounted for by energetic masking in the auditory periphery or whether other effects are involved. Thresholds were determined for combinations of two target frequencies (1 and 8 kHz, two spatial configurations (masker and target either co-located or spatially separated by 90 degrees azimuth, and five different masker types (four complex multi-tone stimuli, one noise masker. A spatial separation of target and masker resulted in a release from masking for all masker types. The amount of masking significantly depended on the masker type and frequency range. The various harmonic and inharmonic relations between target and masker or between components of the masker resulted in a complex pattern of increased or decreased masked thresholds in comparison to the predicted energetic masking. The results indicate that harmonicity cues affect the detectability of a tonal target in a complex masker.

  19. Extreme meteorological conditions

    International Nuclear Information System (INIS)

    Altinger de Schwarzkopf, M.L.

    1983-01-01

    Different meteorological variables which may reach significant extreme values, such as the windspeed and, in particular, its occurrence through tornadoes and hurricanes that necesarily incide and wich must be taken into account at the time of nuclear power plants' installation, are analyzed. For this kind of study, it is necessary to determine the basic phenomenum of design. Two criteria are applied to define the basic values of design for extreme meteorological variables. The first one determines the expected extreme value: it is obtained from analyzing the recurence of the phenomenum in a convened period of time, wich may be generally of 50 years. The second one determines the extreme value of low probability, taking into account the nuclear power plant's operating life -f.ex. 25 years- and considering, during said lapse, the occurrence probabilities of extreme meteorological phenomena. The values may be determined either by the deterministic method, which is based on the acknowledgement of the fundamental physical characteristics of the phenomena or by the probabilistic method, that aims to the analysis of historical statistical data. Brief comments are made on the subject in relation to the Argentine Republic area. (R.J.S.) [es

  20. Development of adequate meteorological monitoring standards for safety analysis of nuclear facilities

    International Nuclear Information System (INIS)

    Alp, E.; Lewis, P.J.

    1985-09-01

    The aim of this report is to identify what constitutes adequate meteorological information for airborne dispersion calculations in case of releases from nuclear facilities during 'normal operation', 'design postulated accidents', and 'emergency situations'. The models used for estimating downwind dispersion are reviewed, including short-range simple terrain, short-range complex terrain and medium to long range models with emphasis on Lagrangian models. The meteorogolical input parameters required for running these models are identified. The methods by which these parameters may be obtained from raw meteorological data are then considered. Emphasis is placed on well-tried and recommended methods rather than those which are currently being developed and lack long-term field tests. The meteorological data required to calculate the parameters that are in turn input to dispersion calculation methods can be obtained mainly from tower measurements. Recommended tower height is 50 m, with two levels of instruments (10 and 50 m) for wind speed, wind direction and temperature. Data for precipitation and solar radiation, that may be required under certain conditions and for special calculations, may be estimated from nearby representative weather stations (if available). For simple terrain, a single tower is sufficient. For complex terrain, such as coastal regions, two towers are desirable for accurate characterization of the turbulence regime in the vicinity of a release site. The report provides the necessary accuracy specifications for instruments required for the meteorological measurements. Data monitoring and recording, maintenance, quality control and assurance are also discussed. Error propagation analyses are recommended to determine the full implications of instrument accuracies on the accuracy of dispersion model predictions. 82 refs

  1. Women in Meteorology.

    Science.gov (United States)

    Lemone, Margaret A.; Waukau, Patricia L.

    1982-11-01

    The names of 927 women who are or have been active in meteorology or closely related fields have been obtained from various sources. Of these women, at least 500 are presently active. An estimated 4-5% of the total number of Ph.D.s in meteorology are awarded to women. About 10% of those receiving B.S. and M.S. degrees are women.The work patterns, accomplishments, and salaries of employed women meteorologists have been summarized from 330 responses to questionnaires, as functions of age, family status, part- or full-time working status, and employing institutions. It was found that women meteorologists holding Ph.D.s are more likely than their male counterparts to be employed by universities. As increasing number of women were employed in operational meteorology, although few of them were married and fewer still responsible for children. Several women were employed by private industry and some had advanced into managerial positions, although at the present time, such positions remain out of the reach of most women.The subjective and objective effects of several gender-related factors have been summarized from the comments and responses to the questionnaires. The primary obstacles to advancement were found to be part-time work and the responsibility for children. Part-time work was found to have a clearly negative effect on salary increase as a function of age. prejudicated discrimination and rules negatively affecting women remain important, especially to the older women, and affirmative action programs are generally seen as beneficial.Surprisingly, in contrast to the experience of women in other fields of science, women Ph.D.s in meteorology earn salaries comparable of their employment in government or large corporations and universities where there are strong affirmative action programs and above-average salaries. Based on the responses to the questionnaire, the small size of the meteorological community is also a factor, enabling women to become recognized

  2. Development and application of artificial neural network models to estimate values of a complex human thermal comfort index associated with urban heat and cool island patterns using air temperature data from a standard meteorological station.

    Science.gov (United States)

    Moustris, Konstantinos; Tsiros, Ioannis X; Tseliou, Areti; Nastos, Panagiotis

    2018-04-11

    The present study deals with the development and application of artificial neural network models (ANNs) to estimate the values of a complex human thermal comfort-discomfort index associated with urban heat and cool island conditions inside various urban clusters using as only inputs air temperature data from a standard meteorological station. The index used in the study is the Physiologically Equivalent Temperature (PET) index which requires as inputs, among others, air temperature, relative humidity, wind speed, and radiation (short- and long-wave components). For the estimation of PET hourly values, ANN models were developed, appropriately trained, and tested. Model results are compared to values calculated by the PET index based on field monitoring data for various urban clusters (street, square, park, courtyard, and gallery) in the city of Athens (Greece) during an extreme hot weather summer period. For the evaluation of the predictive ability of the developed ANN models, several statistical evaluation indices were applied: the mean bias error, the root mean square error, the index of agreement, the coefficient of determination, the true predictive rate, the false alarm rate, and the Success Index. According to the results, it seems that ANNs present a remarkable ability to estimate hourly PET values within various urban clusters using only hourly values of air temperature. This is very important in cases where the human thermal comfort-discomfort conditions have to be analyzed and the only available parameter is air temperature.

  3. Development and application of artificial neural network models to estimate values of a complex human thermal comfort index associated with urban heat and cool island patterns using air temperature data from a standard meteorological station

    Science.gov (United States)

    Moustris, Konstantinos; Tsiros, Ioannis X.; Tseliou, Areti; Nastos, Panagiotis

    2018-04-01

    The present study deals with the development and application of artificial neural network models (ANNs) to estimate the values of a complex human thermal comfort-discomfort index associated with urban heat and cool island conditions inside various urban clusters using as only inputs air temperature data from a standard meteorological station. The index used in the study is the Physiologically Equivalent Temperature (PET) index which requires as inputs, among others, air temperature, relative humidity, wind speed, and radiation (short- and long-wave components). For the estimation of PET hourly values, ANN models were developed, appropriately trained, and tested. Model results are compared to values calculated by the PET index based on field monitoring data for various urban clusters (street, square, park, courtyard, and gallery) in the city of Athens (Greece) during an extreme hot weather summer period. For the evaluation of the predictive ability of the developed ANN models, several statistical evaluation indices were applied: the mean bias error, the root mean square error, the index of agreement, the coefficient of determination, the true predictive rate, the false alarm rate, and the Success Index. According to the results, it seems that ANNs present a remarkable ability to estimate hourly PET values within various urban clusters using only hourly values of air temperature. This is very important in cases where the human thermal comfort-discomfort conditions have to be analyzed and the only available parameter is air temperature.

  4. Resource selection by the California condor (Gymnogyps californianus relative to terrestrial-based habitats and meteorological conditions.

    Directory of Open Access Journals (Sweden)

    James W Rivers

    Full Text Available Condors and vultures are distinct from most other terrestrial birds because they use extensive soaring flight for their daily movements. Therefore, assessing resource selection by these avian scavengers requires quantifying the availability of terrestrial-based habitats, as well as meteorological variables that influence atmospheric conditions necessary for soaring. In this study, we undertook the first quantitative assessment of habitat- and meteorological-based resource selection in the endangered California condor (Gymnogyps californianus within its California range and across the annual cycle. We found that condor use of terrestrial areas did not change markedly within the annual cycle, and that condor use was greatest for habitats where food resources and potential predators could be detected and where terrain was amenable for taking off from the ground in flight (e.g., sparse habitats, coastal areas. Condors originating from different release sites differed in their use of habitat, but this was likely due in part to variation in habitats surrounding release sites. Meteorological conditions were linked to condor use of ecological subregions, with thermal height, thermal velocity, and wind speed having both positive (selection and negative (avoidance effects on condor use in different areas. We found little evidence of systematic effects between individual characteristics (i.e., sex, age, breeding status or components of the species management program (i.e., release site, rearing method relative to meteorological conditions. Our findings indicate that habitat type and meteorological conditions can interact in complex ways to influence condor resource selection across landscapes, which is noteworthy given the extent of anthropogenic stressors that may impact condor populations (e.g., lead poisoning, wind energy development. Additional studies will be valuable to assess small-scale condor movements in light of these stressors to help minimize

  5. The Meteorological Monitoring program at a former nuclear weapons plant

    International Nuclear Information System (INIS)

    Maxwell, D.R.; Bowen, B.M.

    1994-01-01

    The purpose of the Meteorological Monitoring program at Rocky Flats Plant (RFP) is to provide meteorological information for use in assessing the transport, and diffusion, and deposition of effluent actually or potentially released into the atmosphere by plant operations. Achievement of this objective aids in protecting health and safety of the public, employees, and environment, and directly supports Emergency Response programs at RFP. Meteorological information supports the design of environmental monitoring networks for impact assessments, environmental surveillance activities, remediation activities, and emergency responses. As the mission of the plant changes from production of nuclear weapons parts to environmental cleanup and economic development, smaller releases resulting from remediation activities become more likely. These possible releases could result from airborne fugitive dust, evaporation from collection ponds, or grass fires

  6. Enhancement of solubility, dissolution release profile and reduction in ulcerogenicity of piroxicam by inclusion complex with skimmed milk.

    Science.gov (United States)

    Sanka, Krishna; Munjulury, Venkata Saidheeraj; Mohd, Abdul Bari; Diwan, Prakash V

    2014-11-01

    Piroxicam (PXM), a non-steroidal anti-inflammatory drug which is poorly soluble in water and ulcerogenic. Milk has been used against the gastric disturbances caused by non-steroidal anti-inflammatory drugs. In this study, skimmed milk (SKM) is used as the carrier for inclusion complex (IC) due to its surface active agent and amino acid content. To enhance the solubility, dissolution rate and prevent ulcerogenicity of PXM though IC with SKM. IC of PXM were prepared with SKM by solvent evaporation method using rota evaporator and were evaluated for solubility, dissolution, solid state characterization, drug excipient interaction, rat intestinal permeation, ulcerogenicity and histopathological studies. Solubility of PXM was enhanced 2.5 times with IC. The dissolution release and amount of PXM permeated through rat small intestine was enhanced significantly with IC. Decreases in the gastric lesion index values of IC were observed than physical mixture (PM) and free PXM. The histopathological studies revealed significant reduction in ulceration in rat stomach after treatment with IC. It is concluded that SKM is a good carrier to prepare IC of PXM for oral administration.

  7. Nano-encapsulation of olive leaf phenolic compounds through WPC-pectin complexes and evaluating their release rate.

    Science.gov (United States)

    Mohammadi, Adeleh; Jafari, Seid Mahdi; Assadpour, Elham; Faridi Esfanjani, Afshin

    2016-01-01

    In this study, W/O micro-emulsions as primary emulsions and a complex of whey protein concentrate (WPC) and pectin in the external aqueous phase were used to produce W/O/W emulsions. Average droplet size of primary W/O emulsion and multiple emulsions stabilized by WPC or WPC-pectin after one day of production was 6.16, 675.7 and 1443 nm, respectively, which achieved to 22.97, 347.7 and, 1992.4 nm after 20 days storage without any sedimentation. The encapsulation efficiency of phenolic compounds for stabilized W/O/W emulsions with WPC and WPC-pectin were 93.34% and 96.64%, respectively, which was decreased to 72.73% and 88.81% at 20th storage day. The lowest release of phenolics observed in multiple emulsions of WPC-pectin. These results suggest that nano-encapsulation of olive leaf extract within inner aqueous phase of W/O/W emulsions was successful, and there could be a high potential for the application of olive leaf extract in fortification of food products. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Mapping the Martian Meteorology

    Science.gov (United States)

    Allison, M.; Ross, J. D.; Solomon, N.

    1999-01-01

    The Mars-adapted version of the NASA/GISS general circulation model (GCM) has been applied to the hourly/daily simulation of the planet's meteorology over several seasonal orbits. The current running version of the model includes a diurnal solar cycle, CO2 sublimation, and a mature parameterization of upper level wave drag with a vertical domain extending from the surface up to the 6microb level. The benchmark simulations provide a four-dimensional archive for the comparative evaluation of various schemes for the retrieval of winds from anticipated polar orbiter measurements of temperatures by the Pressure Modulator Infrared Radiometer. Additional information is contained in the original extended abstract.

  9. Air pollution meteorology

    Energy Technology Data Exchange (ETDEWEB)

    Shirvaikar, V V; Daoo, V J [Environmental Assessment Div., Bhabha Atomic Research Centre, Mumbai (India)

    2002-06-01

    This report is intended as a training cum reference document for scientists posted at the Environmental Laboratories at the Nuclear Power Station Sites and other sites of the Department of Atomic Energy with installations emitting air pollutants, radioactive or otherwise. Since a manual already exists for the computation of doses from radioactive air pollutants, a general approach is take here i.e. air pollutants in general are considered. The first chapter presents a brief introduction to the need and scope of air pollution dispersion modelling. The second chapter is a very important chapter discussing the aspects of meteorology relevant to air pollution and dispersion modelling. This chapter is important because without this information one really does not understand the phenomena affecting dispersion, the scope and applicability of various models or their limitations under various weather and site conditions. The third chapter discusses the air pollution models in detail. These models are applicable to distances of a few tens of kilometres. The fourth chapter discusses the various aspects of meteorological measurements relevant to air pollution. The chapters are followed by two appendices. Apendix A discusses the reliability of air pollution estimates. Apendix B gives some practical examples relevant to general air pollution. It is hoped that the document will prove very useful to the users. (author)

  10. Meteorological data assimilation for real-time emergency response

    International Nuclear Information System (INIS)

    Sugiyama, G.; Chan, S.T.

    1996-11-01

    The US Department of Energy's Atmospheric Release Advisory Capability (ARAC) provides real-time dose assessments of airborne pollutant releases. Diverse data assimilation techniques are required to meet the needs of a new generation of ARAC models and to take advantage of the rapidly expanding availability of meteorological data. We are developing a hierarchy of algorithms to provide gridded meteorological fields which can be used to drive dispersion codes or to provide initial fields for mesoscale models. Data to be processed include winds, temperature, moisture, and turbulence

  11. Modified gum Arabic hydrogels as matrices for controlled release of curcumin supramolecular complexes; Hidrogeis de goma arabica modificada como matrizes para libertacao controlada de complexos supramoleculares de curcumina

    Energy Technology Data Exchange (ETDEWEB)

    Gerola, Adriana P.; Silva, Danielle C., E-mail: avalente@ci.uc.pt [Department of Chemistry, University of Coimbra, Coimbra (Portugal); Rubira, Adley F.; Muniz, Edvani C. [Universidade Estadual de Maringa (GMPC/UEM), PR (Brazil). Grupo de Materiais Polimericos e Compositos; Jesus, Sandra; Borges, Olga [Faculty of Pharmacy, University of Coimbra, Coimbra (Portugal)

    2015-07-01

    Modified gum Arabic (GA) hydrogels show a pH-responsive behavior making them excellent matrices to be used for oral administration of drugs. Our goal is to study the behavior of those matrices in simulated gastric and intestinal fluids. In this work we will present how the methacrylation degree of GA, by using glycidyl methacrylate, can affect the properties of these hydrogels for controlled release. The drug used in this work is the curcumin (Cur). Cur is associated with numerous pharmacological activities, but their application is limited by the low water solubility. We will present some studies involving the formation of host-guest complexes between Cur and natural cyclodextrins. Both modified GA and hydrogels were characterized by different techniques. The kinetics release of Cur complex-containing modified GA hydrogels was studied to have an insight on the release mechanism and rate constants. Toxicity studies on undifferentiated and differentiated Caco-2 were also carried out. (author)

  12. Stabilization of diastolic calcium signal via calcium pump regulation of complex local calcium releases and transient decay in a computational model of cardiac pacemaker cell with individual release channels.

    Directory of Open Access Journals (Sweden)

    Alexander V Maltsev

    2017-08-01

    Full Text Available Intracellular Local Ca releases (LCRs from sarcoplasmic reticulum (SR regulate cardiac pacemaker cell function by activation of electrogenic Na/Ca exchanger (NCX during diastole. Prior studies demonstrated the existence of powerful compensatory mechanisms of LCR regulation via a complex local cross-talk of Ca pump, release and NCX. One major obstacle to study these mechanisms is that LCR exhibit complex Ca release propagation patterns (including merges and separations that have not been characterized. Here we developed new terminology, classification, and computer algorithms for automatic detection of numerically simulated LCRs and examined LCR regulation by SR Ca pumping rate (Pup that provides a major contribution to fight-or-flight response. In our simulations the faster SR Ca pumping accelerates action potential-induced Ca transient decay and quickly clears Ca under the cell membrane in diastole, preventing premature releases. Then the SR generates an earlier, more synchronized, and stronger diastolic LCR signal activating an earlier and larger inward NCX current. LCRs at higher Pup exhibit larger amplitudes and faster propagation with more collisions to each other. The LCRs overlap with Ca transient decay, causing an elevation of the average diastolic [Ca] nadir to ~200 nM (at Pup = 24 mM/s. Background Ca (in locations lacking LCRs quickly decays to resting Ca levels (<100 nM at high Pup, but remained elevated during slower decay at low Pup. Release propagation is facilitated at higher Pup by a larger LCR amplitude, whereas at low Pup by higher background Ca. While at low Pup LCRs show smaller amplitudes, their larger durations and sizes combined with longer transient decay stabilize integrals of diastolic Ca and NCX current signals. Thus, the local interplay of SR Ca pump and release channels regulates LCRs and Ca transient decay to insure fail-safe pacemaker cell operation within a wide range of rates.

  13. Atlantic Oceanographic and Meteorological Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Atlantic Oceanographic and Meteorological Laboratory conducts research to understand the physical, chemical, and biological characteristics and processes of the...

  14. Meteorology ans solar physics

    Science.gov (United States)

    Schwarz, Oliver

    When in the second half of the 19th century both solar physics and astrophysics came into existence, various solar phenomena were described by analogies encountered in the terrestrial atmosphere. For a certain time, meteorology played a central role in research on solar processes. At first glance, this may appear as a curious and old-fashioned specialty. However, solar physics owes its first insights into solar structure to various analogies in terrestrial atmospheric studies. The present investigation intends to elucidate this fact, to present details of the historical development, and to demonstrate how our present knowledge in certain fields is based on considerations which were originally taken from the description of the terrestrial atmosphere.

  15. Meteorology as an infratechnology

    Science.gov (United States)

    Williams, G. A.; Smith, L. A.

    2003-04-01

    From an economists perspective, meteorology is an underpinning or infratechnology in the sense that in general it does not of its own accord lead to actual products. Its value added comes from the application of its results to the activities of other forms of economic and technological activity. This contribution discusses both the potential applications of meteorology as an ininfratechnology, and quantifying its socio-economic impact. Large economic and social benefits are both likely in theory and can be identified in practice. Case studies of particular weather dependent industries or particular episodes are suggested, based on the methodology developed by NIST to analyze the social impact of technological innovation in US industries (see www.nist.gov/director/planning/strategicplanning.htm ). Infratechnologies can provide economic benefits in the support of markets. Incomplete information is a major cause of market failure because it inhibits the proper design of contracts. The performance of markets in general can be influenced by strategies adopted by different firms within a market to regulate the performance of others especially suppliers or purchasers. This contribution will focus on benefits to society from mechanisms which enhance and enforce mitigating actions. When the market mechanism fails, who might social benefits be gained, for example, by widening the scope of authorities to ensure that those who could have taken mitigating action, given prior warning, cover the costs. This goes beyond the design and implementation of civil responses to severe weather warnings to include the design of legislative recourse in the event of negligence given prior knowledge, or the modification of insurance contracts. The aim here, for example, would be to avoid the loss of an oil tanker in heavy seas at a location where a high probability of heavy seas had been forecast for some time.

  16. The role of hyaluronan as a drug carrier to enhance the bioavailability of extended release ophthalmic formulations. Hyaluronan-timolol ionic complexes as a model case.

    Science.gov (United States)

    Battistini, F D; Tártara, L I; Boiero, C; Guzmán, M L; Luciani-Giaccobbe, L C; Palma, S D; Allemandi, D A; Manzo, R H; Olivera, M E

    2017-07-15

    The aim of this work was to obtain information concerning the properties of ophthalmic formulations based on hyaluronic-drug ionic complexes, to identify the factors that determine the onset, intensity and duration of the pharmacotherapeutic effect. Dispersions of a complex of 0.5% w/v of sodium hyaluronate (HyNa) loaded with 0.5% w/v of timolol maleate (TM) were obtained and presented a counterionic condensation higher than 75%. For comparison a similar complex obtained with hyaluronic acid (HyH) was also prepared. Although the viscosity of HyNa-TM was significantly higher than that of HyH-TM, in vitro release of TM from both complexes showed a similar extended drug release profile (20-31% over 5h) controlled by diffusion and ionic exchange. Ocular pharmacokinetic study performed in normotensive rabbits showed that HyNa-TM complex exhibited attractive bioavailability properties in the aqueous humor (AUC and Cmax significantly higher and later Tmax) compared to commercial TM eye-drops. Moreover, a more prolonged period of lowered intra-ocular pressure (10h) and a more intense hypotensive activity was observed after instillation of a drop of HyNa-TM as compared to the eye-drops. Such behavior was related to the longer pre-corneal residence times (400%) observed with HyNa-TM complex. No significant changes in rabbit transcorneal permeation were detected upon complexation. These results demonstrate that the ability of HyNa to modulate TM release, together with its mucoadhesiveness related to the viscosity, affected both the pharmacokinetic and pharmacodynamic parameters. The HyNa-TM complex is a potentially useful carrier for ocular drug delivery, which could improve the TM efficacy and reduce the frequency of administration to improve patient compliance. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Hydrophobic ion pairing of a minocycline/Ca(2+)/AOT complex for preparation of drug-loaded PLGA nanoparticles with improved sustained release.

    Science.gov (United States)

    Holmkvist, Alexander Dontsios; Friberg, Annika; Nilsson, Ulf J; Schouenborg, Jens

    2016-02-29

    Polymeric nanoparticles is an established and efficient means to achieve controlled release of drugs. Incorporation of minocycline, an antibiotic with anti-inflammatory and neuroprotective properties, into biodegradable nanoparticles may therefore provide an efficient means to combat foreign body reactions to implanted electrodes in the brain. However, minocycline is commonly associated with poor encapsulation efficiencies and/or fast release rates due to its high solubility in water. Moreover, minocycline is unstable under conditions of low and high pH, heat and exposure to light, which exacerbate the challenges of encapsulation. In this work drug loaded PLGA nanoparticles were prepared by a modified emulsification-solvent-diffusion technique and characterized for size, drug encapsulation and in vitro drug release. A novel hydrophobic ion pair complex of minocycline, Ca(2+) ions and the anionic surfactant AOT was developed to protect minocycline from degradation and prolong its release. The optimized formulation resulted in particle sizes around 220 nm with an entrapment efficiency of 43% and showed drug release over 30 days in artificial cerebrospinal fluid. The present results constitute a substantial increase in release time compared to what has hitherto been achieved for minocycline and indicate that such particles might provide useful for sustained drug delivery in the CNS. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  18. What governs successful performance of a complex whole body movement: The Kovacs release-regrasp on horizontal bar?

    Science.gov (United States)

    Hiley, Michael J; Yeadon, Maurice R

    2016-12-08

    The Kovacs is a release and regrasp skill performed on the horizontal bar in men׳s artistic gymnastics. It is a popular skill in elite competitive gymnastics with over 40% of male gymnasts performing a variation of the Kovacs at the London 2012 Olympics. In the qualifying competition 84% of Kovacs were successfully regrasped, with the remaining 16% resulting in a fall. The aim of the present study was to determine why some gymnasts are more successful than others at regrasping the bar, with a secondary aim to determine how a less successful gymnast could alter his technique in order to become more successful. Nine performances of the Kovacs by each of two gymnasts, one 100% successful and one 11% successful, were analysed to determine differences in release and regrasp parameters. The technique of the less successful gymnast was optimised using a computer simulation model to increase the percentage of catches (success rate). The successful gymnast had larger and more consistent release windows and a radial velocity towards the bar at regrasp. The less successful gymnast had higher horizontal velocity at release and a mean radial velocity away from the bar at regrasp. Optimising his simulated technique increased the rate of success from 11% to 93%. The actions prior to release were performed earlier than in the recorded performances leading to a more vertical path of the mass centre at release and a radial velocity towards the bar at regrasp. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Meteorological experiments for emergency preparedness. part 1

    International Nuclear Information System (INIS)

    Leao, I.L.B.; Nicolli, D.

    1993-12-01

    Since the preliminary studies for the Angra dos Reis Nuclear Power Plant (NPP) siting, by an American consultant company, it was verified that the micro scale and mesoscale meteorological conditions in the region show a unique complex pattern, so that no similar nuclear installation site could be found for reference. Therefore, it was recommended to install onsite a correspondingly complex meteorological data acquisition system which comprises a 100-meter tower with instruments at three different levels and three 15-meter satellite towers on the hills around. In this report, are described the equipment and instruments sent by the IAEA to CNEN as well as the procedures and particular computer programming developed by the staff. It is also reported on the bureaucratic problems and meager budget allocation for the Project which delayed the installation of the two meteorological stations and hindered the implementation of the Project. The equipment for the atmospheric boundary layer sounding were used for the first time in September 1993, when CNEN provided some resource for the purchase of gas and batteries. The first atmospheric sounding campaign showed the occurrence of strong night winds and intense thermal inversion at the higher level of the boundary layer, until now unknown by the Brazilian meteorologists. By way of this report, the staff of meteorologists tries to show the status of Project BRA/09/031 and the know-how gained with it. (author)

  20. Operative meteorological data base in Forsmark

    International Nuclear Information System (INIS)

    Appelgren, A.; Hallberg, B.; Nordlinder, S.

    1990-01-01

    This report describes how data collected during a field measurement campaign were analysed and compiled to create a data base for operative use. The data base gives information about the wind and the atmospheric stability at five locations around the Forsmark nuclear power plant. In the measurement campaign, sodar systems and a 100 m high tower at Forsmark were used. Temperature, wind speed and wind direction were measured by sensors on the tower, while wind speed and direction, and the standard deviation of the vertical wind, were monitored by the sodar systems. This gave meteorological data from several heights. At Forsmark, the temperature difference and the wind speed from the tower were used to determine the atmospheric stability. At the sodar locations, the stability was deduced by employing a scheme which considered the season, the time of day, the wind direction and the wind speed. To create the operative data base, the wind speeds and wind directions, respectively, from two locations at the time were correlated. A code for graphical and numerical presentation of the data from the data base was developed. A special system of warnings was included, featuring notification about phenomena such as sea breeze, warnings about large variation in the wind conditions within the area, and warnings for situations in which the meteorological conditions make the results from the atmospheric dispersion calculations uncertain. This feature was implemented to alert the user to the fact that ordinary dispersion and dose calculations, using meteorological data from a single point, might give erroneous results. The operative data base and the presentation code were integrated with the dispersion and dose calculation code AIRPAC/EMMA, which is to be used in case of increased releases from nuclear power plants. The possibility to use the data from the operative data base in the dispersion calculations was investigated. It was found that a modification of AIRPAC/EMMA, in such a

  1. Protein S-glutathionylation lowers superoxide/hydrogen peroxide release from skeletal muscle mitochondria through modification of complex I and inhibition of pyruvate uptake.

    Directory of Open Access Journals (Sweden)

    Robert M Gill

    Full Text Available Protein S-glutathionylation is a reversible redox modification that regulates mitochondrial metabolism and reactive oxygen species (ROS production in liver and cardiac tissue. However, whether or not it controls ROS release from skeletal muscle mitochondria has not been explored. In the present study, we examined if chemically-induced protein S-glutathionylation could alter superoxide (O2●-/hydrogen peroxide (H2O2 release from isolated muscle mitochondria. Disulfiram, a powerful chemical S-glutathionylation catalyst, was used to S-glutathionylate mitochondrial proteins and ascertain if it can alter ROS production. It was found that O2●-/H2O2 release rates from permeabilized muscle mitochondria decreased with increasing doses of disulfiram (100-500 μM. This effect was highest in mitochondria oxidizing succinate or palmitoyl-carnitine, where a ~80-90% decrease in the rate of ROS release was observed. Similar effects were detected in intact mitochondria respiring under state 4 conditions. Incubation of disulfiram-treated mitochondria with DTT (2 mM restored ROS release confirming that these effects were associated with protein S-glutathionylation. Disulfiram treatment also inhibited phosphorylating and proton leak-dependent respiration. Radiolabelled substrate uptake experiments demonstrated that disulfiram inhibited pyruvate import but had no effect on carnitine uptake. Immunoblot analysis of complex I revealed that it contained several protein S-glutathionylation targets including NDUSF1, a subunit required for NADH oxidation. Taken together, these results demonstrate that O2●-/H2O2 release from muscle mitochondria can be altered by protein S-glutathionylation. We attribute these changes to the protein S-glutathionylation complex I and inhibition of mitochondrial pyruvate carrier.

  2. Instruments for meteorological measurement

    International Nuclear Information System (INIS)

    1983-08-01

    The Fundamental Safety Rules applicable to certain types of nuclear installation are intended to clarify the conditions of which observance, for the type of installation concerned and for the subject that they deal with, is considered as equivalent to compliance with regulatory French technical practice. These Rules should facilitate safety analysises and the clear understanding between persons interested in matters related to nuclear safety. They in no way reduce the operator's liability and pose no obstacle to statutory provisions in force. For any installation to which a Fundamental Safety Rule applies according to the foregoing paragraph, the operator may be relieved from application of the Rule if he shows proof that the safety objectives set by the Rule are attained by other means that he proposes within the framework of statutory procedures. Furthermore, the Central Service for the Safety of Nuclear Installations reserves the right at all times to alter any Fundamental Safety Rule, as required, should it deem this necessary, while specifying the applicability conditions. This present rule has for objective to determine the means for meteorological measurement near a site of nuclear facility in which there is not a PWR power plant [fr

  3. Using a combination of radiogenic and stable isotopes coupled with hydrogeochemistry, limnometrics and meteorological data in hydrological research of complex underground mine-pit lake systems: The case of Cueva de la Mora

    Science.gov (United States)

    Sánchez-España, J.; Diez Ercilla, M.; Pérez Cerdán, F.; Yusta, I.

    2012-04-01

    This study presents a combination of radiogenic and stable isotopes (3H, 2H and 18O on pit lake water, and 34S on dissolved sulfate) coupled with bathymetric, meteorological and limnometric investigations, and detailed hydrogeochemical studies to decipher the flooding history and hydrological dynamics of a meromictic and deeply stratified pit lake in SW Spain. The application of these combined techniques has been specially succesful considering the complexity of the studied system, which includes a substantial number of horizontal galleries, shafts and large rooms physically connected to the pit lake. Specific conductance and temperature profiles have depicted a physical structure of the water body which includes four monimolimnetic layers of increasing density with depth. This internal configuration includes m-scale layers separated by sharp transional zones and is rarely observed in natural, fresh water bodies and most other pit lakes. The tritium abundance of the different layers indicate that the deepest water consists in strongly acidified and metal-laden meteoric water infiltrated in the mine system soon after the mine closure in 1971-72. Oxygen and hydrogen isotope ratios of the different layers reflect a sharp stratification with increasing evaporative influence towards the lake surface. The combination of tritium data with the oxygen and hydrogen isotope composition of the different layers suggests a model of pit lake formation with an initial stage of flooding (with entrance of highly metal- and sulfate-loaded mine drainage from the underlying mine galleries) that deeply determined the physical structure and meromictic nature of the lake. After reaching the present water level and morphology, the stagnant, anoxic part of pit lake seems to have remained chemically and isotopically unmodified during its 40 year-old history. Although the pit lake receives significant water input during autumn and winter (which in turn provoke significant volumetric increases

  4. [Influence of LDAO on the conformation and release of bacteriochlorophyll of peripheral light-harvesting complex (LH2) from Rhodobacter azotoformans].

    Science.gov (United States)

    Zhao, Gen-gui; Dong, Yan-min; Yang, Su-ping; Jiao, Nian-zhi; Qu, Yin-bo

    2010-10-01

    The aim of this study is to reveal the interaction relationships between lauryl dimethylamine N-oxide (LDAO) and peripheral light-harvesting complex (LH2) as well as the influence of LDAO on structure and function of LH2. In the present work, the effects of LDAO on the conformation and release processes of bacteriochlorophyll (BChl) of LH2 when incubated under different temperature and pH in the presence and absence of LDAO were investigated by spectroscopy. The results indicated that (1) the presence of LDAO resulted in alterations in the conformation, alpha-helix content, and spectra of Tyr and B850 band of LH2 at room temperature and pH 8.0. Moreover, energy transfer efficiency of LH2 was enhanced markedly in the presence of LDAO. (2) At 60 degrees C, both the B800 and B850 band of LH2 were released and transited into free BChl at pH 8.0. However, the release rates of bacteriochlorophylls of B800 and B850 band from LH2 were slowed down and the release processes were changed when incubated in the presence of LDAO. Hence, the stability of LH2 was improved in the presence of LDAO. (3) The accelerated release processes of bacteriochlorophylls of B800 and B850 band of LH2 were induced to transform into bacteriopheophytin (BPhe) and free BChl by LDAO in strong acid and strong alkalic solution at room temperature. However, the kinetic patterns of the B800 and B850 band were remarkably different. The release and self-assemble processes of B850 in LH2 were observed in strong acid solution without LDAO. Therefore, the different release behaviors of B800 and B850 of LH2 are induced by LDAO under different extreme environmental conditions.

  5. The Physico-Mechanical Properties and Release Kinetics of Eugenol in Chitosan-Alginate Polyelectrolyte Complex Films as Active Food Packaging

    Directory of Open Access Journals (Sweden)

    Baiq Amelia Riyandari

    2018-02-01

    Full Text Available A study of eugenol release and its kinetics model from chitosan-alginate polyelectrolyte complex (PEC films has been conducted. Some factors that affected the eugenol release were also studied, including the composition of chitosan-alginate PEC and the concentration of eugenol. The chitosan-alginate-eugenol PEC films were synthesized at pH ± 4.0, then the PEC films were characterized using a Fourier-transform infrared spectroscopy (FTIR spectrophotometer. An investigation of the films’ properties was also conducted, including morphology analysis using a scanning electron microscope (SEM, differential thermal analysis (DTA / thermogravimetric analysis (TGA, mechanical strength, transparency testing, water absorption, and water vapor permeability. The release of eugenol was investigated through in vitro assay in ethanol 96% (v/v for four days, and the concentration of eugenol was measured using an ultraviolet-visible (UV-Vis spectrophotometer. The characterization of the films using FTIR showed that the formation of PEC occurred through ionic interaction between the amine groups (–NH3+of the chitosan and the carboxylate groups (–COO– of the alginate. The result showed that the composition of chitosan-alginate PEC and the concentration of eugenol can affect the release of eugenol from PEC films. A higher concentration of alginate and eugenol could increase the concentration of eugenol that was released from the films. The mechanism for the release of eugenol from chitosan-alginate PEC films followed the Korsmeyer-Peppas model with an n value of < 0.5, which means the release mechanism for eugenol was controlled by a Fickian diffusion process. The antioxidant activity assay of the films using the 2,2-diphenyl-1-picrylhydrazyl (DPPH method resulted in a high radical scavenging activity (RSA value of 55.99% in four days.

  6. Environmental significance of copper, lead, manganese, uranium and zinc speciation in the event of contaminated waters release from the Ranger Uranium Mining Complex

    International Nuclear Information System (INIS)

    Noller, B.N.; Currey, N.A.

    1983-01-01

    The likely impact of the accidental release of tailings dam water during the dry season at the Ranger Uranium Mining Complex was examined. A speciation scheme utilising sizing by filtration and ion-exchange with Chelex 100 has given an insight into the likely partitioning of zinc, copper, lead, manganese and uranium following the addition of tailings dam water to samples from waterbodies in the vicinity of the uranium mining/milling complex. The speciation findings are discussed in terms of likely toxic effects on fish

  7. The meteorological data acquisition system

    International Nuclear Information System (INIS)

    Bouharrour, S.; Thomas, P.

    1975-07-01

    The 200 m meteorological tower of the Karlsruhe Nuclear Research Center has been equipped with 45 instruments measuring the meteorological parameters near the ground level. Frequent inquiry of the instruments implies data acquisition with on-line data reduction. This task is fulfilled by some peripheral units controlled by a PDP-8/I. This report presents details of the hardware configuration and a short description of the software configuration of the meteorological data acquisition system. The report also serves as an instruction for maintenance and repair work to be carried out at the system. (orig.) [de

  8. Particulate Matter Dispersion (PM10, with interrelation of topographic and meteorological factors

    Directory of Open Access Journals (Sweden)

    Alvaro Javier Arrieta-Fuentes

    2016-07-01

    Full Text Available Mining-industrial processes carried out by anthropic action, bring the generation of impacts to the environment. Between the impacts associated with mining is the involvement of the air quality produced by the release of atmospheric pollutants, being subject to study the behavior of the respirable fraction of particulate matter less than 10 microns (PM10 with respect to meteorological and topographical factors. The analyzed scenarios in the study involved daily and annual exposure times of PM10, in wich modeling with AERMOD View Software was made. The model was carried out in two topographic zones, a complex area, located in the municipality of Socha and a simple area located in the municipality of Sogamoso. It was used meteorological data type satellite, in format .SAM for modeled areas. Three types of emission sources were identified in the areas; considering that the disperse fixed emission sources predominate, followed by the mobile sources and point sources were found in low proportion. PM10 dispersion models made for the zones of simple and complex topography, gave as result that direction and the wind speed is conditioned by the type of zone. It allowed a free flow in the predominant direction in wind rose to the area of simple topography and a turbulent flow in the complex area. It was determined that the sources of emission of PM10 in both cases are local scale; They presented a critical radius of drag and deposition of particles of 200 m approximately.

  9. Tannic acid promotes ion release of copper oxide nanoparticles: Impacts from solution pH change and complexation reactions.

    NARCIS (Netherlands)

    Zhao, Jing; Liu, Yang; Pan, Bo; Gao, Guoqian; Liu, Ying; Liu, Siqian; Liang, Ni; Zhou, Dandan; Vijver, Martina G; Peijnenburg, Willie J G M

    2017-01-01

    The increasing number of applications in which copper oxide nanoparticles (CuO NPs) are used, may lead to potential release of CuO NPs into the environment. However, the impact of natural organic matters on the behavior and fate of CuO NPs in aquatic media is still largely unknown. In this study,

  10. Unraveling the complexities of the velocity dependency of E. coli retention and release parameters in saturated porous media.

    Science.gov (United States)

    Sasidharan, Salini; Bradford, Scott A; Torkzaban, Saeed; Ye, Xueyan; Vanderzalm, Joanne; Du, Xinqiang; Page, Declan

    2017-12-15

    Escherichia coli transport and release experiments were conducted to investigate the pore-water velocity (v) dependency of the sticking efficiency (α), the fraction of the solid surface area that contributed to retention (S f ), the percentage of injected cells that were irreversibly retained (M irr ), and cell release under different (10-300mM) ionic strength (IS) conditions. Values of α, S f , and M irr increased with increasing IS and decreasing v, but the dependency on v was greatest at intermediate IS (30 and 50mM). Following the retention phase, successive increases in v up to 100 or 150mday -1 and flow interruption of 24h produced negligible amounts of cell release. However, excavation of the sand from the columns in excess electrolyte solution resulted in the release of >80% of the retained bacteria. These observations were explained by: (i) extended interaction energy calculations on a heterogeneous sand collector; (ii) an increase in adhesive strength with the residence time; and (iii) torque balance consideration on rough surfaces. In particular, α, S f , and M irr increased with IS due to lower energy barriers and stronger primary minima. The values of α, S f , and M irr also increased with decreasing v because the adhesive strength increased with the residence time (e.g., an increased probability to diffuse over the energy barrier) and lower hydrodynamic forces diminished cell removal. The controlling influence of lever arms at microscopic roughness locations and grain-grain contacts were used to explain negligible cell removal with large increases in v and large amounts of cell recovery following sand excavation. Results reveal the underlying causes (interaction energy, torque balance, and residence time) of the velocity dependency of E. coli retention and release parameters (k sw , α, and S f ) that are not accounted for in colloid filtration theory. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Mathematical problems in meteorological modelling

    CERN Document Server

    Csomós, Petra; Faragó, István; Horányi, András; Szépszó, Gabriella

    2016-01-01

    This book deals with mathematical problems arising in the context of meteorological modelling. It gathers and presents some of the most interesting and important issues from the interaction of mathematics and meteorology. It is unique in that it features contributions on topics like data assimilation, ensemble prediction, numerical methods, and transport modelling, from both mathematical and meteorological perspectives. The derivation and solution of all kinds of numerical prediction models require the application of results from various mathematical fields. The present volume is divided into three parts, moving from mathematical and numerical problems through air quality modelling, to advanced applications in data assimilation and probabilistic forecasting. The book arose from the workshop “Mathematical Problems in Meteorological Modelling” held in Budapest in May 2014 and organized by the ECMI Special Interest Group on Numerical Weather Prediction. Its main objective is to highlight the beauty of the de...

  12. Defense Meteorological Satellite Program (DMSP)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Defense Meteorological Satellite Program (DMSP) satellites collect visible and infrared cloud imagery as well as monitoring the atmospheric, oceanographic,...

  13. Average wind statistics for SRP area meteorological towers

    International Nuclear Information System (INIS)

    Laurinat, J.E.

    1987-01-01

    A quality assured set of average wind Statistics for the seven SRP area meteorological towers has been calculated for the five-year period 1982--1986 at the request of DOE/SR. A Similar set of statistics was previously compiled for the years 1975-- 1979. The updated wind statistics will replace the old statistics as the meteorological input for calculating atmospheric radionuclide doses from stack releases, and will be used in the annual environmental report. This report details the methods used to average the wind statistics and to screen out bad measurements and presents wind roses generated by the averaged statistics

  14. Release of dissolved phosphorus from riparian wetlands: Evidence for complex interactions among hydroclimate variability, topography and soil properties.

    Science.gov (United States)

    Gu, Sen; Gruau, Gérard; Dupas, Rémi; Rumpel, Cornélia; Crème, Alexandra; Fovet, Ophélie; Gascuel-Odoux, Chantal; Jeanneau, Laurent; Humbert, Guillaume; Petitjean, Patrice

    2017-11-15

    In agricultural landscapes, establishment of vegetated buffer zones in riparian wetlands (RWs) is promoted to decrease phosphorus (P) emissions because RWs can trap particulate P from upslope fields. However, long-term accumulation of P risks the release of dissolved P, since the unstable hydrological conditions in these zones may mobilize accumulated particulate P by transforming it into a mobile dissolved P species. This study evaluates how hydroclimate variability, topography and soil properties interact and influence this mobilization, using a three-year dataset of molybdate-reactive dissolved P (MRDP) and total dissolved P (TDP) concentrations in soil water from two RWs located in an agricultural catchment in western France (Kervidy-Naizin), along with stream P concentrations. Two main drivers of seasonal dissolved P release were identified: i) soil rewetting during water-table rise after dry periods and ii) reductive dissolution of soil Fe (hydr)oxides during prolonged water saturation periods. These mechanisms were shown to vary greatly in space (according to topography) and time (according to intra- and interannual hydroclimate variability). The concentration and speciation of the released dissolved P also varied spatially depending on soil chemistry and local topography. Comparison of sites revealed a similar correlation between soil P speciation (percentage of organic P ranging from 35-70%) and the concentration and speciation of the released P (MRDP from topography and soil chemistry must be considered to decrease the risk of remobilizing legacy soil P when establishing riparian buffer zones in agricultural landscapes. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Carbon dioxide diffuse emission and thermal energy release from hydrothermal systems at Copahue-Caviahue Volcanic Complex (Argentina)

    Science.gov (United States)

    Chiodini, Giovanni; Cardellini, Carlo; Lamberti, María Clara; Agusto, Mariano; Caselli, Alberto; Liccioli, Caterina; Tamburello, Giancarlo; Tassi, Franco; Vaselli, Orlando; Caliro, Stefano

    2015-10-01

    The north-western sector of Caviahue caldera (Argentina), close to the active volcanic system of Copahue, is characterized by the presence of several hydrothermal sites that host numerous fumarolic emissions, anomalous soil diffuse degassing of CO2 and hot soils. In March 2014, measurements of soil CO2 fluxes in 5 of these sites (namely, Las Máquinas, Las Maquinitas I, Las Maquinitas II, Anfiteatro, and Termas de Copahue) allowed an estimation that 165 t of deeply derived CO2 is daily released. The gas source is likely related to a relatively shallow geothermal reservoir containing a single vapor phase as also suggested by both the geochemical data from the 3 deep wells drilled in the 1980s and gas geoindicators applied to the fumarolic discharges. Gas equilibria within the H-C-O gas system indicate the presence of a large, probably unique, single phase vapor zone at 200-210 °C feeding the hydrothermal manifestations of Las Máquinas, Las Maquinitas I and II and Termas de Copahue. A natural thermal release of 107 MW was computed by using CO2 as a tracer of the original vapor phase. The magmatic signature of the incondensable fumarolic gases, the wide expanse of the hydrothermal areas and the remarkable high amount of gas and heat released by fluid expulsion seem to be compatible with an active magmatic intrusion beneath this portion of the Caviahue caldera.

  16. A novel gel based on an ionic complex from a dendronized polymer and ciprofloxacin: Evaluation of its use for controlled topical drug release

    Energy Technology Data Exchange (ETDEWEB)

    García, Mónica C. [Unidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), CONICET and Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, X5000HUA Córdoba (Argentina); Cuggino, Julio C. [Instituto de Desarrollo Tecnológico para la Industria Química (INTEC), CONICET, Colectora Ruta Nac. N° 168, km. 0, Pje. El Pozo, 3000 Santa Fe (Argentina); Rosset, Clarisa I.; Páez, Paulina L. [Unidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), CONICET and Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, X5000HUA Córdoba (Argentina); Strumia, Miriam C. [Instituto Multidisciplinario de Biología Vegetal (IMBIV), CONICET and Laboratorio de Materiales Poliméricos (LAMAP), Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, X5000HUA Córdoba (Argentina); and others

    2016-12-01

    The development and characterization of a novel, gel-type material based on a dendronized polymer (DP) loaded with ciprofloxacin (CIP), and the evaluation of its possible use for controlled drug release, are presented in this work. DP showed biocompatible and non-toxic behaviors in cultured cells, both of which are considered optimal properties for the design of a final material for biomedical applications. These results were encouraging for the use of the polymer loaded with CIP (as a drug model), under gel form, in the development of a new controlled-release system to be evaluated for topical administration. First, DP-CIP ionic complexes were obtained by an acid-base reaction using the high density of carboxylic acid groups of the DP and the amine groups of the CIP. The complexes obtained in the solid state were broadly characterized using FTIR spectroscopy, XRP diffraction, DSC-TG analysis and optical microscopy techniques. Gels based on the DP-CIP complexes were easily prepared and presented excellent mechanical behaviors. In addition, optimal properties for application on mucosal membranes and skin were achieved due to their high biocompatibility and acute skin non-irritation. Slow and sustained release of CIP toward simulated physiological fluids was observed in the assays (in vitro), attributed to ion exchange phenomenon and to the drug reservoir effect. An in vitro bacterial growth inhibition assay showed significant CIP activity, corresponding to 38 and 58% of that exhibited by a CIP hydrochloride solution at similar CIP concentrations, against Staphylococcus aureus and Pseudomonas aeruginosa, respectively. However, CIP delivery was appropriate, both in terms of magnitude and velocity to allow for a bactericidal effect. In conclusion, the final product showed promising behavior, which could be exploited for the treatment of topical and mucosal opportunistic infections in human or veterinary applications. - Highlights: • A novel hydrogel based on

  17. A novel gel based on an ionic complex from a dendronized polymer and ciprofloxacin: Evaluation of its use for controlled topical drug release

    International Nuclear Information System (INIS)

    García, Mónica C.; Cuggino, Julio C.; Rosset, Clarisa I.; Páez, Paulina L.; Strumia, Miriam C.

    2016-01-01

    The development and characterization of a novel, gel-type material based on a dendronized polymer (DP) loaded with ciprofloxacin (CIP), and the evaluation of its possible use for controlled drug release, are presented in this work. DP showed biocompatible and non-toxic behaviors in cultured cells, both of which are considered optimal properties for the design of a final material for biomedical applications. These results were encouraging for the use of the polymer loaded with CIP (as a drug model), under gel form, in the development of a new controlled-release system to be evaluated for topical administration. First, DP-CIP ionic complexes were obtained by an acid-base reaction using the high density of carboxylic acid groups of the DP and the amine groups of the CIP. The complexes obtained in the solid state were broadly characterized using FTIR spectroscopy, XRP diffraction, DSC-TG analysis and optical microscopy techniques. Gels based on the DP-CIP complexes were easily prepared and presented excellent mechanical behaviors. In addition, optimal properties for application on mucosal membranes and skin were achieved due to their high biocompatibility and acute skin non-irritation. Slow and sustained release of CIP toward simulated physiological fluids was observed in the assays (in vitro), attributed to ion exchange phenomenon and to the drug reservoir effect. An in vitro bacterial growth inhibition assay showed significant CIP activity, corresponding to 38 and 58% of that exhibited by a CIP hydrochloride solution at similar CIP concentrations, against Staphylococcus aureus and Pseudomonas aeruginosa, respectively. However, CIP delivery was appropriate, both in terms of magnitude and velocity to allow for a bactericidal effect. In conclusion, the final product showed promising behavior, which could be exploited for the treatment of topical and mucosal opportunistic infections in human or veterinary applications. - Highlights: • A novel hydrogel based on

  18. A Smart Europium-Ruthenium Complex as Anticancer Prodrug: Controllable Drug Release and Real-Time Monitoring under Different Light Excitations.

    Science.gov (United States)

    Li, Hongguang; Xie, Chen; Lan, Rongfeng; Zha, Shuai; Chan, Chi-Fai; Wong, Wing-Yan; Ho, Ka-Lok; Chan, Brandon Dow; Luo, Yuxia; Zhang, Jing-Xiang; Law, Ga-Lai; Tai, William C S; Bünzli, Jean-Claude G; Wong, Ka-Leung

    2017-11-09

    A unique, dual-function, photoactivatable anticancer prodrug, RuEuL, has been tailored that features a ruthenium(II) complex linked to a cyclen-europium chelate via a π-conjugated bridge. Under irradiation at 488 nm, the dark-inactive prodrug undergoes photodissociation, releasing the DNA-damaging ruthenium species. Under evaluation-window irradiation (λ irr = one-photon 350 nm or two-photon 700 nm), the drug delivery process can be quantitatively monitored in real-time because of the long-lived red europium emission. Linear relationships between released drug concentration and ESI-MS or luminescence responses are established. Finally, the efficiency of the new prodrug is demonstrated both in vitro RuEuL anticancer prodrug over some existing ones and open the way for decisive improvements in multipurpose prodrugs.

  19. Core-shell nanofibers of curcumin/cyclodextrin inclusion complex and polylactic acid: Enhanced water solubility and slow release of curcumin.

    Science.gov (United States)

    Aytac, Zeynep; Uyar, Tamer

    2017-02-25

    Core-shell nanofibers were designed via electrospinning using inclusion complex (IC) of model hydrophobic drug (curcumin, CUR) with cyclodextrin (CD) in the core and polymer (polylactic acid, PLA) in the shell (cCUR/HPβCD-IC-sPLA-NF). CD-IC of CUR and HPβCD was formed at 1:2 molar ratio. The successful formation of core-shell nanofibers was revealed by TEM and CLSM images. cCUR/HPβCD-IC-sPLA-NF released CUR slowly but much more in total than PLA-CUR-NF at pH 1 and pH 7.4 due to the restriction of CUR in the core of nanofibers and solubility improvement shown in phase solubility diagram, respectively. Improved antioxidant activity of cCUR/HPβCD-IC-sPLA-NF in methanol:water (1:1) is related with the solubility enhancement achieved in water based system. The slow reaction of cCUR/HPβCD-IC-sPLA-NF in methanol is associated with the shell inhibiting the quick release of CUR. On the other hand, cCUR/HPβCD-IC-sPLA-NF exhibited slightly higher rate of antioxidant activity than PLA-CUR-NF in methanol:water (1:1) owing to the enhanced solubility. To conclude, slow release of CUR was achieved by core-shell nanofiber structure and inclusion complexation of CUR with HPβCD provides high solubility. Briefly, electrospinning of core-shell nanofibers with CD-IC core could offer slow release of drugs as well as solubility enhancement for hydrophobic drugs. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Colloid, adhesive and release properties of nanoparticular ternary complexes between cationic and anionic polysaccharides and basic proteins like bone morphogenetic protein BMP-2.

    Science.gov (United States)

    Petzold, R; Vehlow, D; Urban, B; Grab, A L; Cavalcanti-Adam, E A; Alt, V; Müller, M

    2017-03-01

    Herein we describe an interfacial local drug delivery system for bone morphogenetic protein 2 (BMP-2) based on coatings of polyelectrolyte complex (PEC) nanoparticles (NP). The application horizon is the functionalization of bone substituting materials (BSM) used for the therapy of systemic bone diseases. Nanoparticular ternary complexes of cationic and anionic polysaccharides and BMP-2 or two further model proteins, respectively, were prepared in dependence of the molar mixing ratio, pH value and of the cationic polysaccharide. As further proteins chymotrypsin (CHY) and papain (PAP) were selected, which served as model proteins for BMP-2 due to similar isoelectric points and molecular weights. As charged polysaccharides ethylenediamine modified cellulose (EDAC) and trimethylammonium modified cellulose (PQ10) were combined with cellulose sulphatesulfate (CS). Mixing diluted cationic and anionic polysaccharide and protein solutions according to a slight either anionic or cationic excess charge colloidal ternary dispersions formed, which were cast onto germanium model substrates by water evaporation. Dynamic light scattering (DLS) demonstrated, that these dispersions were colloidally stable for at least one week. Fourier Transform Infrared (FTIR) showed, that the cast protein loaded PEC NP coatings were irreversibly adhesive at the model substrate in contact to HEPES buffer and solely CHY, PAP and BMP-2 were released within long-term time scale. Advantageously, out of the three proteins BMP-2 showed the smallest initial burst and the slowest release kinetics and around 25% of the initial BMP-2 content were released within 14days. Released BMP-2 showed significant activity in the myoblast cells indicating the ability to regulate the formation of new bone. Therefore, BMP-2 loaded PEC NP are suggested as novel promising tool for the functionalization of BSM used for the therapy of systemic bone diseases. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Meteorology/Oceanography Help - Naval Oceanography Portal

    Science.gov (United States)

    section Advanced Search... Sections Home Time Earth Orientation Astronomy Meteorology Oceanography Ice You are here: Home › Help › Meteorology/Oceanography Help USNO Logo USNO Info Meteorology/Oceanography Help Send an e-mail regarding meteorology or oceanography products. Privacy Advisory Your E-Mail

  2. The role of the Finnish Meteorological Institute

    International Nuclear Information System (INIS)

    Savolainen, A.L.; Valkama, I.

    1993-01-01

    The Finnish Meteorological Institute is responsible for the dispersion forecasts for the radiation control in Finland. In addition to the normal weather forecasts the duty forecaster has the work station based three dimensional trajectory model and the short range dispersion model YDINO at his disposal. For expert use, dispersion and dose model TRADOS is available. The TRADOS, developed by the Finnish Meteorological Institute and by the Technical Research Centre of Finland, includes a meteorological data base that utilizes the numerical forecasts of the High Resolution Limited Area Model (HIRLAM) weather prediction model. The transport is described by three-dimensional air-parcel trajectories. For each time step the integrated air concentrations as well as dry and wet deposition for selected groups of radionuclides are computed. In the operational emergency application only external dose rates are computed. In the statistical version also individual and population dose estimates via several external and internal pathways can be made. The TRADOS is currently run under two separate user interfaces. The trajectory and dispersion model interface includes ready-made lists of the nuclear power plants and other installations. The dose model has a set of release terms for several groups of radionuclides. There is also a graphical module that enables the computed results to be presented in grid or also isolines. A new graphical user interface and presentation lay-outs redesigned as visual and end-user friendly as possible and with the aim of possible and with the aim of possible adoption as a Nordic standard will be installed in the near future. (orig.)

  3. Survival, differentiation, and neuroprotective mechanisms of human stem cells complexed with neurotrophin-3-releasing pharmacologically active microcarriers in an ex vivo model of Parkinson's disease.

    Science.gov (United States)

    Daviaud, Nicolas; Garbayo, Elisa; Sindji, Laurence; Martínez-Serrano, Alberto; Schiller, Paul C; Montero-Menei, Claudia N

    2015-06-01

    Stem cell-based regenerative therapies hold great potential for the treatment of degenerative disorders such as Parkinson's disease (PD). We recently reported the repair and functional recovery after treatment with human marrow-isolated adult multilineage inducible (MIAMI) cells adhered to neurotrophin-3 (NT3) releasing pharmacologically active microcarriers (PAMs) in hemiparkinsonian rats. In order to comprehend this effect, the goal of the present work was to elucidate the survival, differentiation, and neuroprotective mechanisms of MIAMI cells and human neural stem cells (NSCs), both adhering to NT3-releasing PAMs in an ex vivo organotypic model of nigrostriatal degeneration made from brain sagittal slices. It was shown that PAMs led to a marked increase in MIAMI cell survival and neuronal differentiation when releasing NT3. A significant neuroprotective effect of MIAMI cells adhering to PAMs was also demonstrated. NSCs barely had a neuroprotective effect and differentiated mostly into dopaminergic neuronal cells when adhering to PAM-NT3. Moreover, those cells were able to release dopamine in a sufficient amount to induce a return to baseline levels. Reverse transcription-quantitative polymerase chain reaction and enzyme-linked immunosorbent assay analyses identified vascular endothelial growth factor (VEGF) and stanniocalcin-1 as potential mediators of the neuroprotective effect of MIAMI cells and NSCs, respectively. It was also shown that VEGF locally stimulated tissue vascularization, which might improve graft survival, without excluding a direct neuroprotective effect of VEGF on dopaminergic neurons. These results indicate a prospective interest of human NSC/PAM and MIAMI cell/PAM complexes in tissue engineering for PD. Stem cell-based regenerative therapies hold great potential for the treatment of degenerative disorders such as Parkinson's disease (PD). The present work elucidates and compares the survival, differentiation, and neuroprotective mechanisms

  4. Atmospheric release advisory capability

    International Nuclear Information System (INIS)

    Sullivan, T.J.

    1981-01-01

    The ARAC system (Atmospheric Release Advisory Capability) is described. The system is a collection of people, computers, computer models, topographic data and meteorological input data that together permits a calculation of, in a quasi-predictive sense, where effluent from an accident will migrate through the atmosphere, where it will be deposited on the ground, and what instantaneous and integrated dose an exposed individual would receive

  5. A pH-independent instantaneous release of flurbiprofen: a study of the preparation of complexes, their characterization and in vitro/in vivo evaluation.

    Science.gov (United States)

    Wang, Han-Bing; Yang, Fei-Fei; Gai, Xiu-Mei; Cheng, Bing-Chao; Li, Jin-Yu; Pan, Hao; Yang, Xing-Gang; Pan, Wei-San

    2017-09-01

    In this study, furbiprofen/hydroxypropyl-β-cyclodextrin (HPβCD) inclusion complexes were prepared to improve the drug dissolution and facilitate its application in hydrophilic gels. Inclusion complexes were prepared using a supercritical fluid processing and a conventional optimized co-lypholization method was employed as a reference. The entrapment efficacy and drug loading of both methods were investigated. Evaluation of drug dissolution enhancement was conducted in deionized water as well as buffer solutions of different pH. Carbopol 940 gels of both flurbiprofen and flurbiprofen/HPβCD inclusion complexes, with or without penetration enhancers, were prepared and percutaneous permeation studies were performed using rat abdominal skin samples. Formation of flurbiprofen/HPβCD inclusion complexes was confirmed by Fourier transform-infrared spectroscopy, differential scanning calorimetry, X-ray diffraction and scanning electron microscopy. The results obtained showed that SCF processing produced a higher EE (81.91 ± 1.54%) and DL (6.96 ± 0.17%) compared with OCL with values of 69.11 ± 2.23% and 4.00 ± 1.01%, respectively. A marked instantaneous release of flurbiprofen/HPβCD inclusion complexes prepared by SCF processing (103.04 ± 2.66% cumulative release within 5 min, a 10-fold increase in comparison with flurbiprofen alone) was observed. In addition, this improvement in dissolution was shown to be pH-independent (the percentage cumulative release at pH 1.2, 4.5, 6.8 and 7.4 at 5 min was 95.19 ± 1.71, 101.75 ± 1.44, 105.37 ± 4.58 and 96.84 ± 0.56, respectively). Percutaneous permeability of flurbiprofen-in-HPβCD-in-gels could be significantly accelerated by turpentine oil and was related to the water content in the system. An in vivo pharmacokinetic study showed a 2-fold increase in C max and a shortened T max as well as a comparable relative bioavailability when compared with the commercial flurbiprofen

  6. Design and characterization of controlled-release edible packaging films prepared with synergistic whey-protein polysaccharide complexes.

    Science.gov (United States)

    Liu, Fei; Jiang, Yanfeng; Du, Bingjian; Chai, Zhi; Jiao, Tong; Zhang, Chunyue; Ren, Fazheng; Leng, Xiaojing

    2013-06-19

    This paper describes an investigation into the properties of a doubly emulsified film incorporated with protein-polysaccharide microcapsules, which serves as a multifunctional food packaging film prepared using common edible materials in place of petroleum--based plastics. The relationships between the microstructural properties and controlled release features of a series of water-in-oil-in-water (W/O/W) microcapsulated edible films prepared in thermodynamically incompatible conditions were analyzed. The hydrophilic riboflavin (V(B2)) nano-droplets (13-50 nm) dispersed in α-tocopherol (V(E)) oil phase were embedded in whey protein-polysaccharide (WPs) microcapsules with a shell thickness of 20-56 nm. These microcapsules were then integrated in 103 μm thick WPs films. Different polysaccharides, including gum arabic (GA), low-methoxyl pectin (LMP), and κ-carrageenan (KCG), exhibited different in vitro synergistic effects on the ability of both films to effect enteric controlled release of both vitamins. GA, which showed a strong emulsifying ability, also showed better control of V(E) than other polysaccharides, and the highly charged KCG showed better control of V(B2) than GA did.

  7. Site evaluation using measured meteorology data

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, R. E.; Rusche, B. C. [Savannah River Lab., E.I. du Pont de Nemours and Co., Aiken, South Carolina (United States)

    1967-07-01

    A key factor in reactor site evaluation is the frequency of occurrence of various dispersion conditions and this relationship to potential off-site doses following a reactor accident. Detailed measurements of the wind speed, wind direction, and temperature at heights up to 1200 ft at the Savannah River Plant form the basis for a comprehensive analysis of the frequency of occurrence of potential off-site doses. A complete set of data was taken about every five minutes, and 107,000 sets (about one year of data) were analyzed. The meteorology data were converted to ordinary dispersion parameters through correlating equations developed at Brookhaven National Laboratory. The results were expressed on curves in dose per unit release of activity vs distance from the reactor with probability of occurrence as a parameter. Separate sets of curves were calculated for releases of noble gas and of halogens and at release heights of 200 ft (a nominal stack height) and of 850 ft (about the height of the tallest power plant stacks). Additional curves were developed to show dose as a function of direction and probability of occurrence. In addition to the dose frequency distribution analyses performed as a function of height of release, direction, and distance; more conventional frequency distributions of wind speed, wind direction, and thermal stability were developed as a function of height. All the analyses were carried out on the IBM 360/65. These results represent the first known analysis utilizing data up to 1200 ft and taken often enough to develop reliable frequency distributions for a short term release. (author)

  8. Future directions of meteorology related to air-quality research.

    Science.gov (United States)

    Seaman, Nelson L

    2003-06-01

    Meteorology is one of the major factors contributing to air-pollution episodes. More accurate representation of meteorological fields has been possible in recent years through the use of remote sensing systems, high-speed computers and fine-mesh meteorological models. Over the next 5-20 years, better meteorological inputs for air quality studies will depend on making better use of a wealth of new remotely sensed observations in more advanced data assimilation systems. However, for fine mesh models to be successful, parameterizations used to represent physical processes must be redesigned to be more precise and better adapted for the scales at which they will be applied. Candidates for significant overhaul include schemes to represent turbulence, deep convection, shallow clouds, and land-surface processes. Improvements in the meteorological observing systems, data assimilation and modeling, coupled with advancements in air-chemistry modeling, will soon lead to operational forecasting of air quality in the US. Predictive capabilities can be expected to grow rapidly over the next decade. This will open the way for a number of valuable new services and strategies, including better warnings of unhealthy atmospheric conditions, event-dependent emissions restrictions, and now casting support for homeland security in the event of toxic releases into the atmosphere.

  9. Meteorological tracers in regional planning

    International Nuclear Information System (INIS)

    Mueller, K.H.

    1974-11-01

    Atmospheric tracers can be used as indicators to study both the ventilation of an urban region and its dispersion meteorology for air pollutants. A correlation analysis applied to the space-time dependent tracer concentrations is able to give transfer functions, the structure and characteristic parameters of which describe the meteorological and topographical situation of the urban region and its surroundings in an integral manner. To reduce the number of persons usually involved in a tracer experiment an automatic air sampling system had to be developed

  10. Site-specific meteorology identification for DOE facility accident analysis

    International Nuclear Information System (INIS)

    Rabin, S.B.

    1995-01-01

    Currently, chemical dispersion calculations performed for safety analysis of DOE facilities assume a Pasquill D-Stability Class with a 4.5 m/s windspeed. These meteorological conditions are assumed to conservatively address the source term generation mechanism as well as the dispersion mechanism thereby resulting in a net conservative downwind consequence. While choosing this Stability Class / Windspeed combination may result in an overall conservative consequence, the level of conservative can not be quantified. The intent of this paper is to document a methodology which incorporates site-specific meteorology to determine a quantifiable consequence of a chemical release. A five-year meteorological database, appropriate for the facility location, is utilized for these chemical consequence calculations, and is consistent with the approach used for radiological releases. The hourly averages of meteorological conditions have been binned into 21 groups for the chemical consequence calculations. These 21 cases each have a probability of occurrence based on the number of times each case has occurred over the five year sampling period. A code has been developed which automates the running of all the cases with a commercially available air modeling code. The 21 cases are sorted by concentration. A concentration may be selected by the user for a quantified level of conservatism. The methodology presented is intended to improve the technical accuracy and defensability of Chemical Source Term / Dispersion Safety Analysis work. The result improves the quality of safety analyses products without significantly increasing the cost

  11. Microparticles obtained by complex coacervation: influence of the type of reticulation and the drying process on the release of the core material

    Directory of Open Access Journals (Sweden)

    Izabela Dutra Alvim

    2010-12-01

    Full Text Available Microparticles obtained by complex coacervation were crosslinked with glutaraldehyde or with transglutaminase and dried using freeze drying or spray drying. Moist samples presented Encapsulation Efficiency (%EE higher than 96%. The mean diameters ranged from 43.7 ± 3.4 to 96.4 ± 10.3 µm for moist samples, from 38.1 ± 5.36 to 65.2 ± 16.1 µm for dried samples, and from 62.5 ± 7.5 to 106.9 ± 26.1 µm for rehydrated microparticles. The integrity of the particles without crosslinking was maintained when freeze drying was used. After spray drying, only crosslinked samples were able to maintain the wall integrity. Microparticles had a round shape and in the case of dried samples rugged walls apparently without cracks were observed. Core distribution inside the particles was multinuclear and homogeneous and core release was evaluated using anhydrous ethanol. Moist particles crosslinked with glutaraldehyde at the concentration of 1.0 mM.g-1 protein (ptn, were more efficient with respect to the core retention compared to 0.1 mM.g-1 ptn or those crosslinked with transglutaminase (10 U.g-1 ptn. The drying processes had a strong influence on the core release profile reducing the amount released to all dry samples

  12. Development of Novel Antisense Oligonucleotides for the Functional Regulation of RNA-Induced Silencing Complex (RISC) by Promoting the Release of microRNA from RISC.

    Science.gov (United States)

    Ariyoshi, Jumpei; Momokawa, Daiki; Eimori, Nao; Kobori, Akio; Murakami, Akira; Yamayoshi, Asako

    2015-12-16

    MicroRNAs (miRNAs) are known to be important post-transcription regulators of gene expression. Aberrant miRNA expression is associated with pathological disease processes, including carcinogenesis. Therefore, miRNAs are considered significant therapeutic targets for cancer therapy. MiRNAs do not act alone, but exhibit their functions by forming RNA-induced silencing complex (RISC). Thus, the regulation of RISC activity is a promising approach for cancer therapy. MiRNA is a core component of RISC and is an essential to RISC for recognizing target mRNA. Thereby, it is expected that development of the method to promote the release of miRNA from RISC would be an effective approach for inhibition of RISC activity. In this study, we synthesized novel peptide-conjugated oligonucleotides (RINDA-as) to promote the release of miRNA from RISC. RINDA-as showed a high rate of miRNA release from RISC and high level of inhibitory effect on RISC activity.

  13. Tech-X Corporation releases simulation code for solving complex problems in plasma physics : VORPAL code provides a robust environment for simulating plasma processes in high-energy physics, IC fabrications and material processing applications

    CERN Multimedia

    2005-01-01

    Tech-X Corporation releases simulation code for solving complex problems in plasma physics : VORPAL code provides a robust environment for simulating plasma processes in high-energy physics, IC fabrications and material processing applications

  14. The Relationship Between the Sesamoid Complex and the First Metatarsal After Hallux Valgus Surgery Without Lateral Soft-Tissue Release: A Prospective Study.

    Science.gov (United States)

    Lamo-Espinosa, José María; Flórez, Borja; Villas, Carlos; Pons-Villanueva, Juan; Bondía, José M; Aquerreta, Jesús Dámaso; Alfonso, Matias

    2015-01-01

    Some investigators have emphasized restoring the relationship between the sesamoid complex and the first metatarsal head to reduce the risk of hallux valgus recurring after surgical reconstruction. In a prospective study, we analyzed whether the first metatarsophalangeal joint could be realigned after scarf-Akin bunionectomy without lateral soft tissue release. A total of 25 feet, in 22 patients, were prospectively enrolled and analyzed using anteroposterior radiographs and coronal computed tomography scans obtained before and 3 months after surgery. The Yildirim sesamoid position decreased from a preoperative of 2 (range 1 to 3) to a postoperative position of 0 (range 0 to 1; p < .001), the mean first intermetatarsal angle decreased from 12.6° ± 2.4° to 5.8° ± 2.1° (p < .001), and the mean distance between the second metatarsal and the tibial sesamoid changed from 25.7 ± 4.6 to 25.9 ± 4.6 (p = .59). Our findings suggest that dislocation of the sesamoid complex is actually caused by displacement of the first metatarsal. In conclusion, the scarf-Akin bunionectomy adequately restores the alignment of the first metatarsophalangeal joint, including restoration of the sesamoid apparatus, without direct plantar-lateral soft tissue release. Copyright © 2015 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

  15. Urban meteorological modelling for nuclear emergency preparedness

    International Nuclear Information System (INIS)

    Baklanov, Alexander; Sorensen, Jens Havskov; Hoe, Steen Cordt; Amstrup, Bjarne

    2006-01-01

    The main objectives of the current EU project 'Integrated Systems for Forecasting Urban Meteorology, Air Pollution and Population Exposure' (FUMAPEX) are the improvement of meteorological forecasts for urban areas, the connection of numerical weather prediction (NWP) models to urban air pollution and population dose models, the building of improved urban air quality information and forecasting systems, and their application in cities in various European climates. In addition to the forecast of the worst air-pollution episodes in large cities, the potential use of improved weather forecasts for nuclear emergency management in urban areas, in case of hazardous releases from nuclear accidents or terror acts, is considered. Such use of NWP data is tested for the Copenhagen metropolitan area and the Oresund region. The Danish Meteorological Institute (DMI) is running an experimental version of the HIRLAM NWP model over Zealand including the Copenhagen metropolitan area with a horizontal resolution of 1.4 km, thus approaching the city-scale. This involves 1-km resolution physiographic data with implications for the urban surface parameters, e.g. surface fluxes, roughness length and albedo. For the city of Copenhagen, the enhanced high-resolution NWP forecasting will be provided to demonstrate the improved dispersion forecasting capabilities of the Danish nuclear emergency preparedness decision-support system, the Accident Reporting and Guidance Operational System (ARGOS), used by the Danish Emergency Management Agency (DEMA). Recently, ARGOS has been extended with a capability of real-time calculation of regional-scale atmospheric dispersion of radioactive material from accidental releases. This is effectuated through on-line interfacing with the Danish Emergency Response Model of the Atmosphere (DERMA), which is run at DMI. For local-scale modelling of atmospheric dispersion, ARGOS utilises the Local-Scale Model Chain (LSMC), which makes use of high-resolution DMI

  16. WJBF TV tower meteorological database for the ERAD Code-1993

    International Nuclear Information System (INIS)

    Weber, A.H.

    1996-07-01

    The Explosive Release Atmospheric Dispersion (ERAD) model (Boughton and DeLaurentis 1992) is a three-dimensional numerical model for simulating atmospheric transport and dispersion. The ERAD code is particularly adept at handling explosive releases into the atmosphere and is being used by the Materials and Accountability Department at the Savannah River Site (SRS) to provide risk estimates. The Environmental Technology Section (ETS) was asked to provide meteorological data to be used for applying ERAD to some site facilities. The ERAD model requires a vertical profile of meteorological measurements. The 1993 data from the WJBF-TV tower has been processed and provided for this purpose. This document describes the steps taken to prepare and format the database

  17. The Atmospheric Release Advisory Capability Site Workstation System

    International Nuclear Information System (INIS)

    Foster, K.T.; Sumikawa, D.A.; Foster, C.S.; Baskett, R.L.

    1993-01-01

    The Atmospheric Release Advisory Capability (ARAC) is a centralized emergency response service that assesses the consequences that may result from an atmospheric release of toxic material. ARAC was developed by the Lawrence Livermore National Laboratory (LLNL) for the Departments of Energy (DOE) and Defense (DOD) and responds principally to radiological accidents. ARAC provides radiological health and safety guidance to decision makers in the form of computer-generated estimates of the effects of an actual, or potential release of radioactive material into the atmosphere. Upon receipt of the release scenario, the ARAC assessment staff extracts meteorological, topographic, and geographic data from resident world-wide databases for use in complex, three-dimensional transport and diffusion models. These dispersion models generate air concentration (or dose) and ground deposition contour plots showing estimates of the contamination patterns produced as the toxic material is carried by the prevailing winds. To facilitate the ARAC response to a release from specific DOE and DOD sites and to provide these sites with a local emergency response tool, a remote Site Workstation System (SWS) is being placed at various ARAC-supported facilities across the country.. This SWS replaces the existing antiquated ARAC Site System now installed at many of these sites. The new system gives users access to complex atmospheric dispersion models that may be run either by the ARAC staff at LLNL, or (in a later phase of the system) by site personnel using the computational resources of the SWS. Supporting this primary function are a variety of SWS-resident supplemental capabilities that include meteorological data acquisition, manipulation of release-specific databases, computer-based communications, and the use of a simpler Gaussian trajectory puff model that is based on Environmental Protection Agency's INPUFF code

  18. Evaporation in hydrology and meteorology

    NARCIS (Netherlands)

    Brandsma, T.

    1990-01-01

    In this paper the role of evaporation in hydrology and meteorology is discussed, with the emphasis on hydrology. The basic theory of evaporation is given and methods to determine evaporation are presented. Some applications of evaporation studies in literature are given in order to illustrate the

  19. A bipyridine-ligated zinc(II) complex with bridging flavonolate ligation: synthesis, characterization, and visible-light-induced CO release reactivity.

    Science.gov (United States)

    Sorenson, Shayne; Popova, Marina; Arif, Atta M; Berreau, Lisa M

    2017-09-01

    Metal-flavonolate compounds are of significant current interest as synthetic models for quercetinase enzymes and as bioactive compounds of importance to human health. Zinc-3-hydroxyflavonolate compounds, including those of quercetin, kampferol, and morin, generally exhibit bidentate coordination to a single Zn II center. The bipyridine-ligated zinc-flavonolate compound reported herein, namely bis(μ-4-oxo-2-phenyl-4H-chromen-3-olato)-κ 3 O 3 :O 3 ,O 4 ;κ 3 O 3 ,O 4 :O 3 -bis[(2,2'-bipyridine-κ 2 N,N')zinc(II)] bis(perchlorate), {[Zn 2 (C 15 H 9 O 3 ) 2 (C 10 H 8 N 2 ) 2 ](ClO 4 ) 2 } n , (1), provides an unusual example of bridging 3-hydroxyflavonolate ligation in a dinuclear metal complex. The symmetry-related Zn II centers of (1) exhibit a distorted octahedral geometry, with weak coordination of a perchlorate anion trans to the bridging deprotonated O atom of the flavonolate ligand. Variable-concentration conductivity measurements provide evidence that, when (1) is dissolved in CH 3 CN, the complex dissociates into monomers. 1 H NMR resonances for (1) dissolved in d 6 -DMSO were assigned via HMQC to the H atoms of the flavonolate and bipyridine ligands. In CH 3 CN, (1) undergoes quantitative visible-light-induced CO release with a quantum yield [0.004 (1)] similar to that exhibited by other mononuclear zinc-3-hydroxyflavonolate complexes. Mass spectroscopic identification of the [(bpy) 2 Zn(O-benzoylsalicylate)] + ion provides evidence of CO release from the flavonol and of ligand exchange at the Zn II center.

  20. Choosing the best meteorological conditions for atmospheric diffusion experiments at the Angra site

    International Nuclear Information System (INIS)

    Nicolli, D.; Thomas, P.

    1983-01-01

    The most appropriate meteorological conditions and time of the day advisable for carrying out diffusion experiments at the Angra site are described. Two emission points were defined, and the sampling area was determined with easy access to the complex terrain taken into consideration. The onsite meteorological measuring system is briefly described. (Author) [pt

  1. Complex weathering in drylands: Implications of ‘stress’ history for rock debris breakdown and sediment release

    Science.gov (United States)

    Warke, P. A.

    2007-03-01

    Weathering studies have often sought to explain features in terms of a prevailing set of environmental conditions. However, it is clear that in most present-day hot desert regions, the surface rock debris has been exposed to a range of weathering environments and processes. These different weathering conditions can arise in two ways, either from the effects of long-term climate change acting on debris that remains relatively static within the landscape or through the spatial relocation of debris from high to low altitude. Consequently, each fragment of rock may contain a unique weathering-related legacy of damage and alteration — a legacy that may greatly influence its response to present-day weathering activity. Experiments are described in which blocks of limestone, sandstone, granite and basalt are given 'stress histories' by subjecting them to varying numbers of heating and freezing cycles as a form of pre-treatment. These imposed stress histories act as proxies for a weathering history. Some blocks were used in a laboratory salt weathering simulation study while others underwent a 2 year field exposure trial at high, mid and low altitude sites in Death Valley, California. Weight loss and ultrasonic pulse velocity measurements suggest that blocks with stress histories deteriorate more rapidly than unstressed samples of the same rock type exposed to the same environmental conditions. Laboratory data also indicate that the result of imposing a known 'weathering history' on samples by pre-stressing them is an increase in the amount of fine sediment released during salt weathering over a given period of time in comparison to unstressed samples.

  2. METEOROLOGICAL INFLUENCES ON VAPOR INCIDENTS IN THE 200 EAST and 200 WEST TANK FARMS FROM CY2001 THRU CY2004

    International Nuclear Information System (INIS)

    FAUROTE, J.M.

    2004-01-01

    Investigation into the meteorological influences on vapor incidents in the tank farms to determine what, if any, meteorological influences contribute to the reporting of odors, smells, vapors, and other gases. Weather phenomena, specifically barometric pressure, and wind velocity and direction can potentially cause or exacerbate a vapor release within the farm systems

  3. Defense Meteorological Satellite Program (DMSP) Film

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The United States Air Force Defense Meteorological Satellite Program (DMSP) Operational Linescan System (OLS) is a polar orbiting meteorological sensor with two...

  4. Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine-poly(ethylene glycol copolymers complexed to oligonucleotides

    Directory of Open Access Journals (Sweden)

    Wheatley Margaret A

    2009-04-01

    Full Text Available Abstract Antisense oligonucleotides (AOs have been shown to induce dystrophin expression in muscles cells of patients with Duchenne Muscular Dystrophy (DMD and in the mdx mouse, the murine model of DMD. However, ineffective delivery of AOs limits their therapeutic potential. Copolymers of cationic poly(ethylene imine (PEI and non-ionic poly(ethylene glycol (PEG form stable nanoparticles when complexed with AOs, but the positive surface charge on the resultant PEG-PEI-AO nanoparticles limits their biodistribution. We adapted a modified double emulsion procedure for encapsulating PEG-PEI-AO polyplexes into degradable polylactide-co-glycolic acid (PLGA nanospheres. Formulation parameters were varied including PLGA molecular weight, ester end-capping, and sonication energy/volume. Our results showed successful encapsulation of PEG-PEI-AO within PLGA nanospheres with average diameters ranging from 215 to 240 nm. Encapsulation efficiency ranged from 60 to 100%, and zeta potential measurements confirmed shielding of the PEG-PEI-AO cationic charge. Kinetic measurements of 17 kDa PLGA showed a rapid burst release of about 20% of the PEG-PEI-AO, followed by sustained release of up to 65% over three weeks. To evaluate functionality, PEG-PEI-AO polyplexes were loaded into PLGA nanospheres using an AO that is known to induce dystrophin expression in dystrophic mdx mice. Intramuscular injections of this compound into mdx mice resulted in over 300 dystrophin-positive muscle fibers distributed throughout the muscle cross-sections, approximately 3.4 times greater than for injections of AO alone. We conclude that PLGA nanospheres are effective compounds for the sustained release of PEG-PEI-AO polyplexes in skeletal muscle and concomitant expression of dystrophin, and may have translational potential in treating DMD.

  5. Meteorological data fields 'in perspective'

    Science.gov (United States)

    Hasler, A. F.; Pierce, H.; Morris, K. R.; Dodge, J.

    1985-01-01

    Perspective display techniques can be applied to meteorological data sets to aid in their interpretation. Examples of a perspective display procedure applied to satellite and aircraft visible and infrared image pairs and to stereo cloud-top height analyses are presented. The procedure uses a sophisticated shading algorithm that produces perspective images with greatly improved comprehensibility when compared with the wire-frame perspective displays that have been used in the past. By changing the 'eye-point' and 'view-point' inputs to the program in a systematic way, movie loops that give the impression of flying over or through the data field have been made. This paper gives examples that show how several kinds of meteorological data fields are more effectively illustrated using the perspective technique.

  6. The antimicrobial efficacy of sustained release silver–carbene complex-loaded l-tyrosine polyphosphate nanoparticles: Characterization, in vitro and in vivo studies

    Science.gov (United States)

    Hindi, Khadijah M.; Ditto, Andrew J.; Panzner, Matthew J.; Medvetz, Douglas A.; Han, Daniel S.; Hovis, Christine E.; Hilliard, Julia K.; Taylor, Jane B.; Yun, Yang H.; Cannon, Carolyn L.; Youngs, Wiley J.

    2009-01-01

    The pressing need to treat multi-drug resistant bacteria in the chronically infected lungs of cystic fibrosis (CF) patients has given rise to novel nebulized antimicrobials. We have synthesized a silver–carbene complex (SCC10) active against a variety of bacterial strains associated with CF and chronic lung infections. Our studies have demonstrated that SCC10-loaded into l-tyrosine polyphosphate nanoparticles (LTP NPs) exhibits excellent antimicrobial activity in vitro and in vivo against the CF relevant bacteria Pseudomonas aeruginosa. Encapsulation of SCC10 in LTP NPs provides sustained release of the antimicrobial over the course of several days translating into efficacious results in vivo with only two administered doses over a 72 h period. PMID:19395021

  7. Technology and Meteorology. An Action Research Paper.

    Science.gov (United States)

    Taggart, Raymond F.

    Meteorology, the science of weather and weather conditions, has traditionally been taught via textbook and rote demonstration. This study was intended to determine to what degree utilizing technology in the study of meteorology improves students' attitudes towards science and to measure to what extent technology in meteorology increases…

  8. Syllabi for Instruction in Agricultural Meteorology.

    Science.gov (United States)

    De Villiers, G. D. B.; And Others

    A working group of the Commission for Agricultural Meteorology has prepared this report to fill a need for detailed syllabi for instruction in agricultural meteorology required by different levels of personnel. Agrometeorological personnel are classified in three categories: (1) professional meteorological personnel (graduates with basic training…

  9. Epicurean Meteorology: Sources, method, scope and organization

    NARCIS (Netherlands)

    Bakker, F.A.

    2016-01-01

    In Epicurean Meteorology Frederik Bakker discusses the meteorology as laid out by Epicurus (341-270 BCE) and Lucretius (1st century BCE). Although in scope and organization their ideas are clearly rooted in the Peripatetic tradition, their meteorology sets itself apart from this tradition by its

  10. Journal of Meteorology and Climate Science

    African Journals Online (AJOL)

    The Journal of Meteorology and Climate Science publishes rigorous theoretical reasoning and advanced empirical research in all areas of Meteorology and Climate Sciences. We welcome articles or proposals from all perspectives and on all subjects pertaining to Meteorology, Agriculture, Humanity, Physics, Geography, ...

  11. Evaporation in hydrology and meteorology

    OpenAIRE

    Brandsma, T.

    1990-01-01

    In this paper the role of evaporation in hydrology and meteorology is discussed, with the emphasis on hydrology. The basic theory of evaporation is given and methods to determine evaporation are presented. Some applications of evaporation studies in literature are given in order to illustrate the theory. Further, special conditions in evaporation are considered, followed by a fotmulation of the difficulties in determining evaporation, The last part of the paper gives a short discussion about ...

  12. Meteorological monitoring for dose assessment and emergency response modeling - how much is enough?

    International Nuclear Information System (INIS)

    Glantz, C.S.

    1990-01-01

    Individuals responsible for emergency response or environmental/dose assessment routinely ask if there are enough meteorological data to adequately support their objectives. The answer requires detailed consideration of the intended applications, capabilities of the atmospheric dispersion model data, pollutant release characteristics, terrain in the modeling region, and size and distribution of the human population in the modeling domain. The meteorologist's detailed knowledge of, and experience in, studying atmospheric transport and diffusion can assist in determining the appropriate level of meteorological monitoring

  13. Release of the cyano moiety in the crystal structure of N-cyanomethyl-N-(2-methoxyethyl)-daunomycin complexed with d(CGATCG).

    Science.gov (United States)

    Saminadin, P; Dautant, A; Mondon, M; Langlois D'estaintot, B; Courseille, C; Précigoux, G

    2000-01-01

    Doxorubicin is among the most widely used anthracycline in cancer chemotherapy. In an attempt to avoid the cardiotoxicity and drug resistance of doxorubicin therapy, several analogues were synthesized. The cyanomorpholinyl derivative is the most cytotoxic. They differ greatly from their parent compound in their biological and pharmacological properties, inducing cross-links in drug DNA complexes. The present study concerns N-cyanomethyl-N-(2-methoxyethyl)-daunomycin (CMDa), a synthetic analogue of cyanomorpholino-daunomycin. Compared to doxorubicin, CMDa displays a cytotoxic activity on L1210 leukemia cells at higher concentration but is effective on doxorubicin resistant cells. The results of fluorescence quenching experiments as well as the melting temperature (DeltaTm = 7.5 degrees C) studies are consistent with a drug molecule which intercalates between the DNA base pairs and stabilizes the DNA double helix. The crystal structure of CMDa complexed to the hexanucleotide d(CGATCG) has been determined at 1.5 A resolution. The complex crystallizes in the space group P41212 and is similar to other anthracycline-hexanucleotide complexes. In the crystal state, the observed densities indicate the formation of N-hydroxymethyl-N-(2-methoxyethyl)-daunomycin (HMDa) with the release of the cyano moiety without DNA alkylation. The formation of this degradation compound is discussed in relation with other drug modifications when binding to DNA. Comparison with two other drug-DNA crystal structures suggests a correlation between a slight change in DNA conformation and the nature of the amino sugar substituents at the N3' position located in the minor groove.

  14. Effect of the Duration of Meteorological Data Collection on the Atmospheric Dispersion Assessment

    International Nuclear Information System (INIS)

    Choi, Yoo-mi; Kim, Eun-hee

    2017-01-01

    This study regards the duration of meteorological data record for a prospective assessment of the environmental impact of gas release from Kori nuclear power plant under normal operation. We compared the atmospheric dispersion factors obtained by employing the meteorological data from 2- and 5-year durations with the corresponding values obtained by employing yearly meteorological data in the period of 2001 to 2008. Influence of the duration of meteorological data collection on short-term atmospheric dispersion factors was previously studied. In this study, long-term dispersion factors were assessed to investigate the influence of the duration of meteorological data collection on the assessment of environmental impact by gas release from Kori nuclear power plant under normal operation. We counted how many yearly meteorological conditions would be represented by 2 or 5 years of long-term data collection. The distribution of shaded cells in Tables I and II indicated that some of the yearly meteorological condition could be properly represented by the conditions averaged over 2- or 5-year durations.

  15. Vulnerability of Cochin Backwaters to meteorological disturbances with special reference to tidal propagation

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, A.; Balachandran, K.K.; Mehra, P.; Desai, R.G.P.; Dabholkar, N.; Kumar, V.; Revichandran, C.; Agarvadekar, Y.

    to meteorological disturbances has significant implications on its ecological and environmental health. Spectral analysis of tides revealed some of the special features of a complex shallow estuary. As the tide propagates into the interior estuary, it undergoes...

  16. An evaluation of meteorologic data differences between the Pantex Plant and Amarillo, Texas

    Energy Technology Data Exchange (ETDEWEB)

    Snyder, S.F.

    1993-06-01

    Meteorologic data from the Pantex Plant and from the nearby National Weather Service (NWS) station at the Amarillo, Texas, International Airport were evaluated to determine if the NWS data adequately represented meteorologic conditions at the Pantex Plant. Annual site environmental dose calculations for the Pantex Plant have previously used the NWS data; information from this data comparison helped determine if future environmental dose calculations should use site-specific Pantex meteorologic data. The meteorologic data evaluated were wind speed, wind direction, and atmospheric stability class. Atmospheric stability class data were compared for years 1990 and 1991 and found to be very similar. Stability class designations were identical and one class different in 63% and 30%, respectively, of the paired hourly data. An unexpected finding was the preponderance of Class D stability, which occurred approximately 62% of the time in both data sets. The overall effect of meteorological differences between the two locations was evaluated by performing environmental dose assessments using the GENII dose assessment computer code. Acute and chronic releases of {sup 3}H and {sup 239}Pu were evaluated. Results using the NWS Amarillo meteorologic data were approximately one-half of those generated using Pantex meteorologic data. The two-fold difference in dose results is within the uncertainty expected from current dose assessment codes; therefore, the two meteorologic databases can be used interchangeably and prior dose calculation results using the NWS Amarillo data are acceptable.

  17. Blast forecasting guide for the Site 300 Meteorology Center

    International Nuclear Information System (INIS)

    Odell, B.N.; Pfeifer, H.E.; Arganbright, V.E.

    1978-01-01

    These step-by-step procedures enable an occasional operator to run the Site 300 Meteorological Center. The primary function of the Center is to determine the maximum weight of high explosives that can be fired at Site 300 under any given meteorological conditions. A secondary function is to supply weather data for other programs such as ARAC (Atmospheric Release Advisory Capability). Included in the primary function are radar and theodolite operations for balloon tracking; calculation of temperatures for various altitudes using Oakland weather obtained from a teletype; computer terminal operation to obtain wind directions, wind velocities, temperatures, and pressure at various altitudes; and methods to determine high-explosive weight limits for simple inversions and focus conditions using pressure-versus-altitude information obtained from the computer. General information is included such as names, telephone numbers, and addresses of maintenance personnel, additional sources of weather information, chart suppliers, balloons, spare parts, etc

  18. Blast forecasting guide for the Site 300 Meteorology Center

    Energy Technology Data Exchange (ETDEWEB)

    Odell, B.N.; Pfeifer, H.E.; Arganbright, V.E.

    1978-06-01

    These step-by-step procedures enable an occasional operator to run the Site 300 Meteorological Center. The primary function of the Center is to determine the maximum weight of high explosives that can be fired at Site 300 under any given meteorological conditions. A secondary function is to supply weather data for other programs such as ARAC (Atmospheric Release Advisory Capability). Included in the primary function are radar and theodolite operations for balloon tracking; calculation of temperatures for various altitudes using Oakland weather obtained from a teletype; computer terminal operation to obtain wind directions, wind velocities, temperatures, and pressure at various altitudes; and methods to determine high-explosive weight limits for simple inversions and focus conditions using pressure-versus-altitude information obtained from the computer. General information is included such as names, telephone numbers, and addresses of maintenance personnel, additional sources of weather information, chart suppliers, balloons, spare parts, etc.

  19. Meteorology and dispersion forecast in nuclear emergency in Argentina

    International Nuclear Information System (INIS)

    Kunst, Juan J.; Boutet, Luis I.; Jordan, Osvaldo D.; Hernandez, Daniel G.; Guichandut, M.E.; Chiappesoni, H.

    2008-01-01

    The 'Nuclear Regulatory Authority (NRA) (ARN in Spanish)' and the 'National Meteorological Office (NMO) (SMN in Spanish)' of Argentine has been working together on the improvement of both meteorological forecasting and dispersion prediction. In the pre-release phase of a nuclear emergency, it is very important to know the wind direction and the forecast of it, to establish the area, around the installation, where the emergency state is declared and to foresee the modification of this area. Information is also needed about deterministic effects, to begin the evacuation. At this time, meteorological forecast of wind direction and speed, and the real time meteorological information is available in the nuclear power plant (NPP) and in the Nuclear Emergency Control Centre at the ARN headquarters, together with the short-range dose calculation provided by our dispersion code, SEDA. By means of the SEDA code, we can estimate the optimum place to measure the radioactive material concentration in air, needed do to reduce evaluation uncertainties due, among others, to poor knowledge of the source term. The SEDA code allows considering atmospheric condition, and the need to reduced doses of the measuring team in charge of the measurements. For the evaluation in the medium range, we participate in the project IXP, which provides four hours and about 50 kilometres forecast. In the long-range movement of air borne radioactivity, the World Meteorological Organization (WMO), whose contact point in Argentina is the SMN, can assist us. We have developed together, with the SMN, a detailed procedure to request assistance from the WMO. In this work, we describe the combined tasks that were carried out with the SMN to define the procedures and the concepts for their application during a real emergency. The results of an application exercise carried out in 2006 are also described. (author)

  20. A risk evaluation model using on-site meteorological data

    International Nuclear Information System (INIS)

    Kang, C.S.

    1979-01-01

    A model is considered in order to evaluate the potential risk from a nuclear facility directly combining the on site meteorological data. The model is utilized to evaluate the environmental consequences from the routine releases during normal plant operation as well as following postulated accidental releases. The doses to individual and risks to the population-at-large are also analyzed in conjunction with design of rad-waste management and safety systems. It is observed that the conventional analysis, which is done in two separate unaffiliated phases of releases and atmospheric dispersion tends to result in unnecessary over-design of the systems because of high resultant doses calculated by multiplication of two extreme values. (author)

  1. Complex Flow Workshop Report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2012-05-01

    This report documents findings from a workshop on the impacts of complex wind flows in and out of wind turbine environments, the research needs, and the challenges of meteorological and engineering modeling at regional, wind plant, and wind turbine scales.

  2. Modelling the meteorological forest fire niche in heterogeneous pyrologic conditions.

    Science.gov (United States)

    De Angelis, Antonella; Ricotta, Carlo; Conedera, Marco; Pezzatti, Gianni Boris

    2015-01-01

    Fire regimes are strongly related to weather conditions that directly and indirectly influence fire ignition and propagation. Identifying the most important meteorological fire drivers is thus fundamental for daily fire risk forecasting. In this context, several fire weather indices have been developed focussing mainly on fire-related local weather conditions and fuel characteristics. The specificity of the conditions for which fire danger indices are developed makes its direct transfer and applicability problematic in different areas or with other fuel types. In this paper we used the low-to-intermediate fire-prone region of Canton Ticino as a case study to develop a new daily fire danger index by implementing a niche modelling approach (Maxent). In order to identify the most suitable weather conditions for fires, different combinations of input variables were tested (meteorological variables, existing fire danger indices or a combination of both). Our findings demonstrate that such combinations of input variables increase the predictive power of the resulting index and surprisingly even using meteorological variables only allows similar or better performances than using the complex Canadian Fire Weather Index (FWI). Furthermore, the niche modelling approach based on Maxent resulted in slightly improved model performance and in a reduced number of selected variables with respect to the classical logistic approach. Factors influencing final model robustness were the number of fire events considered and the specificity of the meteorological conditions leading to fire ignition.

  3. Some directions in laser meteorology

    International Nuclear Information System (INIS)

    Derr, V.E.

    1977-01-01

    Applications of lidar systems in studies of pollution meteorology are discussed. It is pointed out that lidar can contribute to the determination of characteristics of particulate pollutants and also the study of the dynamics of dispersion. Agricultural and energy related problems require both short and longer term forecasting. It is as yet not completely clear whether lidar will be significant in longer term forecasts, of benefit to agriculture and conservation, or whether its usefulness will be primarily in the study of basic atmospheric processes involving the effect of clouds and aerosols on radiation balance. However, recent studies indicate that lidar will be important, in the future, in global wind sensing from satellites. Lidar and radar systems for cloud observations are compared

  4. Optimizing Time Intervals of Meteorological Data Used with Atmospheric Dose Modeling at SRS

    International Nuclear Information System (INIS)

    Simpkins, A.A.

    1999-01-01

    Measured tritium oxide concentrations in air have been compared with calculated values using routine release Gaussian plume models for different time intervals of meteorological data. These comparisons determined an optimum time interval of meteorological data used with atmospheric dose models at the Savannah River Site (SRS). Meteorological data of varying time intervals (1-yr to 10-yr) were used for the comparison. Insignificant differences are seen in using a one-year database as opposed to a five-year database. Use of a ten-year database results in slightly more conservative results. For meteorological databases of length one to five years the mean ratio of predicted to measured tritium oxide concentrations is approximately 1.25 whereas for the ten-year meteorological database the ration is closer to 1.35. Currently at the Savannah River Site a meteorological database of five years duration is used for all dose models. This study suggests no substantially improved accuracy using meteorological files of shorter or longer time intervals

  5. Preliminary results of consequence assessment of a hypothetical severe accident using Thai meteorological data

    Science.gov (United States)

    Silva, K.; Lawawirojwong, S.; Promping, J.

    2017-06-01

    Consequence assessment of a hypothetical severe accident is one of the important elements of the risk assessment of a nuclear power plant. It is widely known that the meteorological conditions can significantly influence the outcomes of such assessment, since it determines the results of the calculation of the radionuclide environmental transport. This study aims to assess the impacts of the meteorological conditions to the results of the consequence assessment. The consequence assessment code, OSCAAR, of Japan Atomic Energy Agency (JAEA) is used for the assessment. The results of the consequence assessment using Thai meteorological data are compared with those using Japanese meteorological data. The Thai case has following characteristics. Low wind speed made the radionuclides concentrate at the center comparing to the Japanese case. The squalls induced the peaks in the ground concentration distribution. The evacuated land is larger than the Japanese case though the relocated land is smaller, which is attributed to the concentration of the radionuclides near the release point.

  6. DESCARTES AND THE METEOROLOGY OF THE WORLD

    Directory of Open Access Journals (Sweden)

    Patrick BRISSEY

    2012-11-01

    Full Text Available Descartes claimed that he thought he could deduce the assumptions of his Meteorology by the contents of the Discourse. He actually began the Meteorology with assumptions. The content of the Discourse, moreover, does not indicate how he deduced the assumptions of the Meteorology. We seem to be left in a precarious position. We can examine the text as it was published, independent of Descartes’ claims, which suggests that he incorporated a presumptive or hypothetical method. On the other hand, we can take Descartes’ claims as our guide and search for the epistemic foundations of the Meteorology independent of the Discourse. In this paper, I will pursue the latter route. My aim is to explain why, and how, Descartes thought that he had deduced the assumptions of the Meteorology. My interest, in this case, is solely Descartes’ physical foundation for the Meteorology, in the physics and physiology that resulted in Descartes’ explanation. With this aim, I provide an interpretation of Descartes’ World where many of its conclusions serve as evidence for the assumptions of the Meteorology. I provisionally conclude that Descartes thought that his World was the epistemic foundation for his Meteorology.

  7. Meteorological Factors Affecting Evaporation Duct Height Climatologies.

    Science.gov (United States)

    1980-07-01

    Italy Maritime Meteorology Division Japan Meteorological Agency Ote-Machi 1-3-4 Chiyoda-Ku Tokyo, Japan Instituto De Geofisica U.N.A.M. Biblioteca ...Torre De Ciencias, 3ER Piso Ciudad Universitaria Mexico 20, D.F. Koninklijk Nederlands Meteorologisch Instituu. Postbus 201 3730 AE Debilt Netherlands

  8. Spatial clustering and meteorological drivers of summer ozone in Europe

    Science.gov (United States)

    Carro-Calvo, Leopoldo; Ordóñez, Carlos; García-Herrera, Ricardo; Schnell, Jordan L.

    2017-10-01

    We have applied the k-means clustering technique on a maximum daily 8-h running average near-surface ozone (MDA8 O3) gridded dataset over Europe at 1° × 1° resolution for summer 1998-2012. This has resulted in a spatial division of nine regions where ozone presents coherent spatiotemporal patterns. The role of meteorology in the variability of ozone at different time scales has been investigated by using daily meteorological fields from the NCEP-NCAR meteorological reanalysis. In the five regions of central-southern Europe ozone extremes (exceedances of the summer 95th percentile) occur mostly under anticyclonic circulation or weak sea level pressure gradients which trigger elevated temperatures and the recirculation of air masses. In the four northern regions extremes are associated with high-latitude anticyclones that divert the typical westerly flow at those latitudes and cause the advection of aged air masses from the south. The impact of meteorology on the day-to-day variability of ozone has been assessed by means of two different types of multiple linear models. These include as predictors meteorological fields averaged within the regions (;region-based; approach) or synoptic indices indicating the degree of resemblance between the daily meteorological fields over a large domain (25°-70° N, 35° W - 35° E) and their corresponding composites for extreme ozone days (;index-based; approach). With the first approach, a reduced set of variables, always including daily maximum temperature within the region, explains 47-66% of the variability (adjusted R2) in central-southern Europe, while more complex models are needed to explain 27-49% of the variability in the northern regions. The index-based approach yields better results for the regions of northern Europe, with adjusted R2 = 40-57%. Finally, both methodologies have also been applied to reproduce the interannual variability of ozone, with the best models explaining 66-88% of the variance in central

  9. A temporal comparison of sex-aggregation pheromone gland content and dynamics of release in three members of the Lutzomyia longipalpis (Diptera: Psychodidae species complex.

    Directory of Open Access Journals (Sweden)

    Mikel A González

    2017-12-01

    Full Text Available Lutzomyia longipalpis is the South American vector of Leishmania infantum, the etiologic agent of visceral leishmaniasis (VL. Male L. longipalpis produce a sex-aggregation pheromone that is critical in mating, yet very little is known about its accumulation over time or factors involved in release. This laboratory study aimed to compare accumulation of pheromone over time and determine factors that might influence release in three members of the L. longipalpis species complex.We investigated male sex-aggregation pheromone gland content at different ages and the release rate of pheromone in the presence or absence of females under different light conditions by gas chromatography-mass spectrometry (GC-MS. Pheromone gland content was determined by extraction of whole males and pheromone release rate was determined by collection of headspace volatiles. Pheromone gland content appeared age-related and pheromone began to accumulate between 6 to 12 h post eclosion and gradually increased until males were 7-9 days old. The greatest amount was detected in 9-day old Campo Grande males ((S-9-methylgermacrene-B; X ± SE: 203.5 ± 57.4 ng/male followed by Sobral 2S males (diterpene; 199.9 ± 34.3 and Jacobina males ((1S,3S,7R-3-methyl-α-himachalene; 128.8 ± 30.3 at 7 days old. Pheromone release was not continuous over time. During a 4-hour period, the greatest quantities of pheromone were released during the first hour, when wing beating activity was most intense. It was then substantially diminished for the remainder of the time. During a 24 h period, 4-5 day old male sand flies released approximately 63 ± 11% of the pheromone content of their glands, depending on the chemotype. The presence of females significantly increased pheromone release rate. The light regime under which the sand flies were held had little influence on pheromone release except on Sobral 2S chemotype.Accumulation of pheromone appears to occur at different rates in the different

  10. A temporal comparison of sex-aggregation pheromone gland content and dynamics of release in three members of the Lutzomyia longipalpis (Diptera: Psychodidae) species complex.

    Science.gov (United States)

    González, Mikel A; Bandi, Krishna K; Bell, Melissa J; Brazil, Reginaldo P; Dilger, Erin; Guerrero, Angel; Courtenay, Orin; Hamilton, James G C

    2017-12-01

    Lutzomyia longipalpis is the South American vector of Leishmania infantum, the etiologic agent of visceral leishmaniasis (VL). Male L. longipalpis produce a sex-aggregation pheromone that is critical in mating, yet very little is known about its accumulation over time or factors involved in release. This laboratory study aimed to compare accumulation of pheromone over time and determine factors that might influence release in three members of the L. longipalpis species complex. We investigated male sex-aggregation pheromone gland content at different ages and the release rate of pheromone in the presence or absence of females under different light conditions by gas chromatography-mass spectrometry (GC-MS). Pheromone gland content was determined by extraction of whole males and pheromone release rate was determined by collection of headspace volatiles. Pheromone gland content appeared age-related and pheromone began to accumulate between 6 to 12 h post eclosion and gradually increased until males were 7-9 days old. The greatest amount was detected in 9-day old Campo Grande males ((S)-9-methylgermacrene-B; X ± SE: 203.5 ± 57.4 ng/male) followed by Sobral 2S males (diterpene; 199.9 ± 34.3) and Jacobina males ((1S,3S,7R)-3-methyl-α-himachalene; 128.8 ± 30.3) at 7 days old. Pheromone release was not continuous over time. During a 4-hour period, the greatest quantities of pheromone were released during the first hour, when wing beating activity was most intense. It was then substantially diminished for the remainder of the time. During a 24 h period, 4-5 day old male sand flies released approximately 63 ± 11% of the pheromone content of their glands, depending on the chemotype. The presence of females significantly increased pheromone release rate. The light regime under which the sand flies were held had little influence on pheromone release except on Sobral 2S chemotype. Accumulation of pheromone appears to occur at different rates in the different chemotypes

  11. Probabilistic approach to external cloud dose calculations using onsite meteorological data

    International Nuclear Information System (INIS)

    Strenge, D.L.; Watson, E.C.; Bander, T.J.; Kennedy, W.E.

    1976-01-01

    A method is described for calculation of external total body and skin doses from accidental atmospheric releases of radionuclides based on hourly onsite meteorological data. The method involves calculation of dose values from a finite size cloud for each hourly observation for a given radionuclide inventory. These values are then used to determine the probability of occurrence of dose levels for specified release times ranging from one hour to 30 days

  12. Meteorological Data Visualization in Multi-User Virtual Reality

    Science.gov (United States)

    Appleton, R.; van Maanen, P. P.; Fisher, W. I.; Krijnen, R.

    2017-12-01

    Due to their complexity and size, visualization of meteorological data is important. It enables the precise examining and reviewing of meteorological details and is used as a communication tool for reporting, education and to demonstrate the importance of the data to policy makers. Specifically for the UCAR community it is important to explore all of such possibilities.Virtual Reality (VR) technology enhances the visualization of volumetric and dynamical data in a more natural way as compared to a standard desktop, keyboard mouse setup. The use of VR for data visualization is not new but recent developments has made expensive hardware and complex setups unnecessary. The availability of consumer of the shelf VR hardware enabled us to create a very intuitive and low cost way to visualize meteorological data. A VR viewer has been implemented using multiple HTC Vive head sets and allows visualization and analysis of meteorological data in NetCDF format (e.g. of NCEP North America Model (NAM), see figure). Sources of atmospheric/meteorological data include radar and satellite as well as traditional weather stations. The data includes typical meteorological information such as temperature, humidity, air pressure, as well as those data described by the climate forecast (CF) model conventions (http://cfconventions.org). Other data such as lightning-strike data and ultra-high-resolution satellite data are also becoming available. The users can navigate freely around the data which is presented in a virtual room at a scale of up to 3.5 X 3.5 meters. The multiple users can manipulate the model simultaneously. Possible mutations include scaling/translating, filtering by value and using a slicing tool to cut-off specific sections of the data to get a closer look. The slicing can be done in any direction using the concept of a `virtual knife' in real-time. The users can also scoop out parts of the data and walk though successive states of the model. Future plans are (a.o.) to

  13. AEROS: a real-time emergency response system for atmospheric releases of toxic material

    International Nuclear Information System (INIS)

    Nasstrom, J.S.; Greenly, G.D.

    1986-01-01

    The Atmospheric Release Advisory Capability (ARAC) at the Lawrence Livermore National Laboratory has developed a sophisticated computer-based real-time emergency response system for radiotoxic releases into the atmosphere. The ARAC Emergency Response Operating System (AEROS) has a centralized computer facility linked to remote site computers, meteorological towers, and meteorological data sources. The system supports certain fixed sites, but has the ability to respond to accidents at arbitrary locations. Product quality and response time are optimized by using complex three-dimensional dispersion models; extensive on-line data bases; automated data processing; and an efficient user interface, employing graphical computer displays and computer-displayed forms. Upon notification, the system automatically initiates a response to an emergency and proceeds through preliminary calculations, automatically processing accident information, meteorological data, and model parameters. The model calculations incorporate mass-consistent three-dimensional wind fields, terrain effects, and particle-in-cell diffusion. Model products are color images of dose or deposition contours overlaid on a base map

  14. Meteorological Data Analysis Using MapReduce

    Directory of Open Access Journals (Sweden)

    Wei Fang

    2014-01-01

    Full Text Available In the atmospheric science, the scale of meteorological data is massive and growing rapidly. K-means is a fast and available cluster algorithm which has been used in many fields. However, for the large-scale meteorological data, the traditional K-means algorithm is not capable enough to satisfy the actual application needs efficiently. This paper proposes an improved MK-means algorithm (MK-means based on MapReduce according to characteristics of large meteorological datasets. The experimental results show that MK-means has more computing ability and scalability.

  15. Communicating meteorology through popular music

    Science.gov (United States)

    Brown, Sally; Aplin, Karen; Jenkins, Katie; Mander, Sarah; Walsh, Claire; Williams, Paul

    2015-04-01

    Previous studies of weather-inspired classical music showed that all forms of music (as well as visual arts and literature) reflect the significance of the environment in society. Here we quantify the extent to which weather has inspired popular musicians, and how weather is represented in English-language pop music. Our work is in press at Weather. Over 750 songs have been identified which were found to refer to meteorological phenomena, mainly in their lyrics, but also in the title of the song, name of the band or songwriter and occasionally in the song's music or sound effects. Over one third of the songs analysed referred to either sun or rain, out of a possible 20 weather categories. It was found that artists use weather to describe emotion, for example, to mirror the changes in a relationship. In this context, rain was broadly seen negatively, and might be used to signify the end of a relationship. Rain could also be perceived in a positive way, such as in songs from more agricultural communities. Wind was the next most common weather phenomenon, but did not represent emotions as much as sun or rain. However, it was the most frequently represented weather type in the music itself, such as in instrumental effects, or non-verbally in choruses. From the limited evidence available, we found that artists were often inspired by a single weather event in writing lyrics, whereas the outcomes were less clearly identifiable from longer periods of good or bad weather. Some artists were influenced more by their environment than others, but they were often inspired to write many songs about their surroundings as part of every-day life, rather than weather in particular. Popular singers and songwriters can therefore emotionally connect their listeners to the environment; this could be exploited to communicate environmental science to a broad audience.

  16. PREVIMER : Meteorological inputs and outputs

    Science.gov (United States)

    Ravenel, H.; Lecornu, F.; Kerléguer, L.

    2009-09-01

    PREVIMER is a pre-operational system aiming to provide a wide range of users, from private individuals to professionals, with short-term forecasts about the coastal environment along the French coastlines bordering the English Channel, the Atlantic Ocean, and the Mediterranean Sea. Observation data and digital modelling tools first provide 48-hour (probably 96-hour by summer 2009) forecasts of sea states, currents, sea water levels and temperatures. The follow-up of an increasing number of biological parameters will, in time, complete this overview of coastal environment. Working in partnership with the French Naval Hydrographic and Oceanographic Service (Service Hydrographique et Océanographique de la Marine, SHOM), the French National Weather Service (Météo-France), the French public science and technology research institute (Institut de Recherche pour le Développement, IRD), the European Institute of Marine Studies (Institut Universitaire Européen de la Mer, IUEM) and many others, IFREMER (the French public institute fo marine research) is supplying the technologies needed to ensure this pertinent information, available daily on Internet at http://www.previmer.org, and stored at the Operational Coastal Oceanographic Data Centre. Since 2006, PREVIMER publishes the results of demonstrators assigned to limited geographic areas and to specific applications. This system remains experimental. The following topics are covered : Hydrodynamic circulation, sea states, follow-up of passive tracers, conservative or non-conservative (specifically of microbiological origin), biogeochemical state, primary production. Lastly, PREVIMER provides researchers and R&D departments with modelling tools and access to the database, in which the observation data and the modelling results are stored, to undertake environmental studies on new sites. The communication will focus on meteorological inputs to and outputs from PREVIMER. It will draw the lessons from almost 3 years during

  17. Inversion of GPS meteorology data

    Directory of Open Access Journals (Sweden)

    K. Hocke

    Full Text Available The GPS meteorology (GPS/MET experiment, led by the Universities Corporation for Atmospheric Research (UCAR, consists of a GPS receiver aboard a low earth orbit (LEO satellite which was launched on 3 April 1995. During a radio occultation the LEO satellite rises or sets relative to one of the 24 GPS satellites at the Earth's horizon. Thereby the atmospheric layers are successively sounded by radio waves which propagate from the GPS satellite to the LEO satellite. From the observed phase path increases, which are due to refraction of the radio waves by the ionosphere and the neutral atmosphere, the atmospheric parameter refractivity, density, pressure and temperature are calculated with high accuracy and resolution (0.5–1.5 km. In the present study, practical aspects of the GPS/MET data analysis are discussed. The retrieval is based on the Abelian integral inversion of the atmospheric bending angle profile into the refractivity index profile. The problem of the upper boundary condition of the Abelian integral is described by examples. The statistical optimization approach which is applied to the data above 40 km and the use of topside bending angle profiles from model atmospheres stabilize the inversion. The retrieved temperature profiles are compared with corresponding profiles which have already been calculated by scientists of UCAR and Jet Propulsion Laboratory (JPL, using Abelian integral inversion too. The comparison shows that in some cases large differences occur (5 K and more. This is probably due to different treatment of the upper boundary condition, data runaways and noise. Several temperature profiles with wavelike structures at tropospheric and stratospheric heights are shown. While the periodic structures at upper stratospheric heights could be caused by residual errors of the ionospheric correction method, the periodic temperature fluctuations at heights below 30 km are most likely caused by atmospheric waves (vertically

  18. Modern history of meteorological services with pictures for a century

    International Nuclear Information System (INIS)

    2004-07-01

    This book deals with modern history of meteorological services with pictures for a century. It is divided into twelve chapters, which mention meteorological services before the Joseon Dynasty period, meteorological observation about surface weather observation, aero logical observation, meteorological satellite, seismometry, observation on yellow dust, and observation on the falling of thunderbolt, weather forecast, meteorological telecommunication, education for weather, research for weather, promotion on weather, international cooperation, main events, special aid on meteorological services, meteorological disaster and the list of the offices for meteorological services.

  19. Interim report on the meteorological database

    International Nuclear Information System (INIS)

    Stage, S.A.; Ramsdell, J.V.; Simonen, C.A.; Burk, K.W.

    1993-01-01

    The Hanford Environmental Dose Reconstruction (HEDR) Project is estimating radiation doses that individuals may have received from operations at Hanford from 1944 to the present. An independent Technical Steering Panel (TSP) directs the project, which is being conducted by the Battelle, Pacific Northwest Laboratories in Richland, Washington. The goals of HEDR, as approved by the TSP, include dose estimates and determination of confidence ranges for these estimates. This letter report describes the current status of the meteorological database. The report defines the meteorological data available for use in climate model calculations, describes the data collection procedures and the preparation and control of the meteorological database. This report also provides an initial assessment of the data quality. The available meteorological data are adequate for atmospheric calculations. Initial checks of the data indicate the data entry accuracy meets the data quality objectives

  20. Index of Meteorological Observations Publication (Before 1890)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Index of meteorological observations in the United States made prior to January 1, 1890, organized by state. Includes station name, coordinates, elevation, period of...

  1. A marine meteorological data acquisition system

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, R.G.P.; Desa, E.; Vithayathil, G.

    A marine meteorological data acquisition system has been developed for long term unattended measurements at remote coastal sites, ocean surface platforms and for use on board research vessels. The system has an open and modular configuration...

  2. NDBC Standard Meteorological Buoy Data, 1970-present

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Data Buoy Center (NDBC) distributes meteorological data from moored buoys maintained by NDBC and others. Moored buoys are the weather sentinels of the...

  3. Ionospheric irregularities in periods of meteorological disturbances

    Science.gov (United States)

    Borchevkina, O. P.; Karpov, I. V.

    2017-09-01

    The results of observations of the total electron content (TEC) in periods of storm disturbances of meteorological situation are presented in the paper. The observational results have shown that a passage of a meteorological storm is accompanied by a substantial decrease in values of TEC and critical frequencies of the ionospheric F2 region. The decreases in values of these ionospheric parameters reach 50% and up to 30% in TEC and critical frequency of the F2 layer, respectively, as compared to meteorologically quiet days. Based on qualitative analysis, it is found that the processes related to formation of local regions of thermospheric heating due to a dissipation of AGW coming into the upper atmosphere from the region of the meteorological disturbance in the lower atmosphere are a possible cause of these ionospheric disturbances.

  4. Meteorological interpretation of transient LOD changes

    Science.gov (United States)

    Masaki, Y.

    2008-04-01

    The Earth’s spin rate is mainly changed by zonal winds. For example, seasonal changes in global atmospheric circulation and episodic changes accompanied with El Nĩ os are clearly detected n in the Length-of-day (LOD). Sub-global to regional meteorological phenomena can also change the wind field, however, their effects on the LOD are uncertain because such LOD signals are expected to be subtle and transient. In our previous study (Masaki, 2006), we introduced atmospheric pressure gradients in the upper atmosphere in order to obtain a rough picture of the meteorological features that can change the LOD. In this presentation, we compare one-year LOD data with meteorological elements (winds, temperature, pressure, etc.) and make an attempt to link transient LOD changes with sub-global meteorological phenomena.

  5. Adaptive Weather Forecasting using Local Meteorological Information

    NARCIS (Netherlands)

    Doeswijk, T.G.; Keesman, K.J.

    2005-01-01

    In general, meteorological parameters such as temperature, rain and global radiation are important for agricultural systems. Anticipating on future conditions is most often needed in these systems. Weather forecasts then become of substantial importance. As weather forecasts are subject to

  6. The 1989 progress report: dynamic meteorology

    International Nuclear Information System (INIS)

    Sadourny, R.

    1989-01-01

    The 1989 progress report of the laboratory of Dynamic Meteorology of the Polytechnic School (France) is presented. The aim of the research programs is the dynamic study of climate and environment in relationship with the global athmospheric behavior. The investigations reported were performed in the fields of: climate modelling, dynamic study of Turbulence, analysis of atmospheric radiation and nebulosity, tropical meteorology and climate, Earth radioactive balance, lidar measurements, middle atmosphere studies. The published papers, the conferences and Laboratory staff are listed [fr

  7. Meteorological circumstances during the 'Chernobyl-period'

    International Nuclear Information System (INIS)

    Ivens, R.; Lablans, W.N.; Wessels, H.R.A.

    1987-01-01

    The progress of the meteorological circumstances and air flows in Europe from 26th April up to 8th May 1986, which caused the spread of contaminated air originating from Chernobyl is outlined and mapped out. Furthermore a global survey is presented of the precipitation in the Netherlands during the period 2nd May to 10th May based on observations of various observation stations of the Royal Dutch Meteorologic Institute (KNMI). 11 figs.; 1 table (H.W.)

  8. Meteorological measurements at nuclear power plants

    International Nuclear Information System (INIS)

    1995-01-01

    On-site meteorological measurements are necessary for evaluating atmospheric dispersion of gaseous effluents. Radiation doses in a plant's vicinity due to these effluents are calculated from the results of dispersion evaluations. The guide addresses the requirements for on-site meteorological measurement systems. Guide YVL 7.3 addresses atmospheric dispersion evaluations and calculation methods, Guide YVL 7.2 radiation dose calculations and Guide YVL 7.8 environmental data reporting. (5 refs.)

  9. Investigations of the adequacy of the meteorological transport model developed for the reactor safety study

    International Nuclear Information System (INIS)

    Spring, J.L.; Brown, W.D.; Church, H.W.; McGrath, P.E.; Ritchie, L.T.; Russo, A.J.; Steck, G.P.; Wayland, J.R.; Blond, R.M.; Wall, I.B.

    1978-01-01

    A computer model (CRAC) was developed for the Reactor Safety Study (WASH-1400) [1] to estimate the consequences of postulated accidents at U.S. commercial nuclear power plants. One hundred reactors at 68 sites were included in the study. The 68 sites were divided into 6 classes according to their geographic location and meteorology. For each site class, a composite population distribution was constructed from the true population distributions at each of the sites comprising that class, and a reference site was chosen for which a full year of meteorological data (wind speed, atmospheric stability, occurrence of rain) was obtained. Given data about a postulated accident (probability, amounts of the released radionuclides, etc.) and the reference reactor site (meteorology, composite population, land usage), CRAC was used to calculate the atmospheric dispersion and ground deposition of the released radionuclides (Gaussian plume submodel) and the health effects (dosimetric and dose response submodels) and costs (land interdiction and decontamination submodel) resulting from their release. The Gaussian plume model used in CRAC either did not treat or treated simplistically a number of meteorological phenomena. Simplified models were used to treat plume rise, inversion layers, and rainstorms, while wind shear, wind direction, and correlations between wind fields and population distributions were not treated at all. Some of the effects of all of these phenomena on predictions of accident consequences as calculated using CRAC have been or are being investigated. The results of these studies are summarized

  10. Modeling the wind-fields of accidental releases with an operational regional forecast model

    International Nuclear Information System (INIS)

    Albritton, J.R.; Lee, R.L.; Sugiyama, G.

    1995-01-01

    The Atmospheric Release Advisory Capability (ARAC) is an operational emergency preparedness and response organization supported primarily by the Departments of Energy and Defense. ARAC can provide real-time assessments of atmospheric releases of radioactive materials at any location in the world. ARAC uses robust three-dimensional atmospheric transport and dispersion models, extensive geophysical and dose-factor databases, meteorological data-acquisition systems, and an experienced staff. Although it was originally conceived and developed as an emergency response and assessment service for nuclear accidents, the ARAC system has been adapted to also simulate non-radiological hazardous releases. For example, in 1991 ARAC responded to three major events: the oil fires in Kuwait, the eruption of Mt. Pinatubo in the Philippines, and the herbicide spill into the upper Sacramento River in California. ARAC's operational simulation system, includes two three-dimensional finite-difference models: a diagnostic wind-field scheme, and a Lagrangian particle-in-cell transport and dispersion scheme. The meteorological component of ARAC's real-time response system employs models using real-time data from all available stations near the accident site to generate a wind-field for input to the transport and dispersion model. Here we report on simulation studies of past and potential release sites to show that even in the absence of local meteorological observational data, readily available gridded analysis and forecast data and a prognostic model, the Navy Operational Regional Atmospheric Prediction System, applied at an appropriate grid resolution can successfully simulate complex local flows

  11. Helicobacter pylori-elicited induction in gastric mucosal matrix metalloproteinase-9 (MMP-9) release involves ERK-dependent cPLA2 activation and its recruitment to the membrane-localized Rac1/p38 complex.

    Science.gov (United States)

    Slomiany, B L; Slomiany, A

    2016-06-01

    Matrix metalloproteinases (MMPs) are a family of endopeptidases implicated in a wide rage of degenerative and inflammatory diseases, including Helicobacter pylori-associated gastritis, and gastric and duodenal ulcer. As gastric mucosal inflammatory responses to H. pylori are characterized by the rise in MMP-9 production, as well as the induction in mitogen-activated protein kinase (MAPK) and Rac1 activation, we investigated the role of Rac1/MAPK in the processes associated with the release of MMP-9. We show that H. pylori LPS-elicited induction in gastric mucosal MMP-9 release is associated with MAPK, ERK and p38 activation, and occurs with the involvement of Rac1 and cytosolic phospholipase A2 (cPLA2). Further, we demonstrate that the LPS-induced MMP-9 release requires ERK-mediated phosphorylation of cPLA2 on Ser(505) that is essential for its membrane localization with Rac1, and that this process necessitates p38 participation. Moreover, we reveal that the activation and membrane translocation of p38 to the Rac1-GTP complex plays a pivotal role in cPLA2-dependent enhancement in MMP-9 release. Hence, our findings provide a strong evidence for the role of ERK/cPLA2 and Rac1/p38/cPLA2 cascade in H. pylori LPS-induced up-regulation in gastric mucosal MMP-9 release.

  12. Influence of ionic complexation on release rate profiles from multiple water-in-oil-in-water (W/O/W) emulsions.

    Science.gov (United States)

    Bonnet, Marie; Cansell, Maud; Placin, Frédéric; David-Briand, Elisabeth; Anton, Marc; Leal-Calderon, Fernando

    2010-07-14

    Water-in-oil-in-water (W/O/W) double emulsions were prepared, and the kinetics of release of magnesium ions from the internal to the external water phase was followed. Different chelating agents (phosvitin and gluconate) were used to bind magnesium within the prospect of improving the ion retention in the internal aqueous droplets. Magnesium release was monitored for 1 month of storage, for each formulation, with and without chelation, at two storage temperatures (4 and 25 degrees C). Leakage occurred without film rupturing (coalescence) and was mainly due to entropically driven diffusion/permeation phenomena. The experimental results revealed a clear correlation between the effectiveness of chelating agents to delay the delivery and their binding capacity characterized by the equilibrium affinity constant. The kinetic data (percent released versus time curves) were interpreted within the framework of a kinetic model based on diffusion and taking into account magnesium chelation.

  13. The Fleet Numerical Meteorology and Oceanography Center (FNMOC) - Naval

    Science.gov (United States)

    Meteorology Oceanography Ice You are here: Home › FNMOC FNMOC Logo FNMOC Navigation Meteorology Products Oceanography Products Tropical Applications Climatology and Archived Data Info The Fleet Numerical Meteorology and Oceanography Center (FNMOC) The Fleet Numerical Meteorology and Oceanography Center (FNMOC

  14. Eighth joint conference on applications of air pollution meteorology with A & WMA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    The eighth Joint Conference on Applications of Air Pollution Meteorology, held January 23-28, 1994, again brings together the American Meteorological Society and Air and Waste Management Association with a broader scientific community to examine the role of the atmosphere on current air quality issues. The CAA Amendments non-attainment title has brought renewed interest in the pairing of complex dynamical meteorological models with photochemical air quality models. Requirements that future attainment to regulations be demonstrated with these models invite a new look at model evaluation. The CAAA titles addressing air toxics have brought renewed interest in near-source dispersion and deposition of toxic chemicals. Consequently, this conference is divided into sessions focusing on topics related to these issues. They include: The Dispersion Environment; Meteorology in Emissions Determination; Long-Range and Mesoscale Pollutant Transport and Fate; Meteorology and Photochemistry; Advanced Dispersion Models and Modeling Systems; Topics in Model Evaluation; Complex Flow Affecting Dispersion Near Structures; and Coastal and Complex Terrain Issues Evaluation.

  15. Summary of Data and Steps for Processing the 1997-2001 SRS Meteorological Database

    International Nuclear Information System (INIS)

    Weber, A.H.

    2003-01-01

    Every five years since the mid-1970s DOE has requested an update on the meteorological conditions at SRS in order to provide dose calculations for accident or routine release scenarios for onsite and offsite populations. The meteorological database includes wind speed, wind direction, temperature, dew point, and horizontal and vertical turbulence intensities. The two most recent databases prior to the current one were completed in 1998 for the time period 1992-96 (Weber, 1998) and one for 1987-91 (Parker, et. al., 1992). The current database covers the period 1997-2001. The advantage of updating the database every five years is that meteorological observations are steadily growing more complete and less subject to errors with the implementation of better electronic data archiving software and hardware, and improved data quality assurance procedures. Also, changes in the region's climate may be manifest

  16. Meteorological monitoring for environmental/dose assessment and emergency response modeling: How much is enough?

    International Nuclear Information System (INIS)

    Glantz, C.S.

    1989-01-01

    In evaluation the effectiveness and appropriateness of meteorological monitoring programs, managers responsible for planning and operating emergency response or environmental/dose assessment systems must routinely question whether enough meteorological data are being obtained to adequately support system applications. There is no simple answer or cookbook procedure that can be followed in generating an appropriate answer to this question. The answer must be developed through detailed consideration of the intended applications for the data, the capabilities of the models that would use the data, pollutant release characteristics, terrain in the modeling region, the size of the modeling domain, and the distribution of human population in the modeling domain. It is recommended that manager consult meteorologists when assessing these factors; the meteorologist's detailed knowledge of, and experience in, studying atmospheric transport and diffusion should assist the manager in determining the appropriate level of meteorological monitoring. 1 ref

  17. Meteorological Drivers of Extreme Air Pollution Events

    Science.gov (United States)

    Horton, D. E.; Schnell, J.; Callahan, C. W.; Suo, Y.

    2017-12-01

    The accumulation of pollutants in the near-surface atmosphere has been shown to have deleterious consequences for public health, agricultural productivity, and economic vitality. Natural and anthropogenic emissions of ozone and particulate matter can accumulate to hazardous concentrations when atmospheric conditions are favorable, and can reach extreme levels when such conditions persist. Favorable atmospheric conditions for pollutant accumulation include optimal temperatures for photochemical reaction rates, circulation patterns conducive to pollutant advection, and a lack of ventilation, dispersion, and scavenging in the local environment. Given our changing climate system and the dual ingredients of poor air quality - pollutants and the atmospheric conditions favorable to their accumulation - it is important to characterize recent changes in favorable meteorological conditions, and quantify their potential contribution to recent extreme air pollution events. To facilitate our characterization, this study employs the recently updated Schnell et al (2015) 1°×1° gridded observed surface ozone and particulate matter datasets for the period of 1998 to 2015, in conjunction with reanalysis and climate model simulation data. We identify extreme air pollution episodes in the observational record and assess the meteorological factors of primary support at local and synoptic scales. We then assess (i) the contribution of observed meteorological trends (if extant) to the magnitude of the event, (ii) the return interval of the meteorological event in the observational record, simulated historical climate, and simulated pre-industrial climate, as well as (iii) the probability of the observed meteorological trend in historical and pre-industrial climates.

  18. Meteorological considerations in emergency response capability at nuclear power plant

    International Nuclear Information System (INIS)

    Fairobent, J.E.

    1985-01-01

    Meteorological considerations in emergency response at nuclear power plants are discussed through examination of current regulations and guidance documents, including discussion of the rationale for current regulatory requirements related to meteorological information for emergency response. Areas discussed include: major meteorological features important to emergency response; onsite meteorological measurements programs, including redundant and backup measurements; access to offsite sources of meteorological information; consideration of real-time and forecast conditions and atmospheric dispersion modeling

  19. A Methodological Inter-Comparison of Gridded Meteorological Products

    Science.gov (United States)

    Newman, A. J.; Clark, M. P.; Longman, R. J.; Giambelluca, T. W.; Arnold, J.

    2017-12-01

    Here we present a gridded meteorology inter-comparison using the state of Hawaíi as a testbed. This inter-comparison is motivated by two general goals: 1) the broad user community of gridded observation based meteorological fields should be aware of inter-product differences and the reasons they exist, which allows users to make informed choices on product selection to best meet their specific application(s); 2) we want to demonstrate the utility of inter-comparisons to meet the first goal, yet highlight that they are limited to mostly generic statements regarding attribution of differences that limits our understanding of these complex algorithms and obscures future research directions. Hawaíi is a useful testbed because it is a meteorologically complex region with well-known spatial features that are tied to specific physical processes (e.g. the trade wind inversion). From a practical standpoint, there are now several monthly climatological and daily precipitation and temperature datasets available that are being used for impact modeling. General conclusions that have emerged are: 1) differences in input station data significantly influence product differences; 2) prediction of precipitation occurrence is crucial across multiple metrics; 3) derived temperature statistics (e.g. diurnal temperature range) may have large spatial differences across products; and 4) attribution of differences to methodological choices is difficult and may limit the outcomes of these inter-comparisons, particularly from a development viewpoint. Thus, we want to continue to move the community towards frameworks that allow for multiple options throughout the product generation chain and allow for more systematic testing.

  20. Air pollutants, meteorology and plant injury

    Energy Technology Data Exchange (ETDEWEB)

    Mukammal, E I; Brandt, C S; Neuwirth, R; Pack, D H; Swinbank, W C

    1968-01-01

    The study of the effect of air pollutants on plant growth inevitably involves meteorological factors, and the World Meteorological Organization has therefore been giving much attention to this matter for some time. Within the Organization, responsibility for this work naturally fell to the Commission for Agricultural Meteorology (CAgM), and following the time-honored procedure in such cases, the Commission established in 1962 a small international group of acknowledged experts to study plant injury and reduction of yield by non-radioactive air pollutants, and charged it with the specific task of preparing a review of present knowledge of the subjects involved. After several years' work, the group fulfilled its appointed task and the resulting report is now published in this WMO Technical Note. 95 references.

  1. Meteorological aspects of siting large wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Hiester, T.R.; Pennell, W.T.

    1981-01-01

    This report, which focuses on the meteorological aspects of siting large wind turbines (turbines with a rated output exceeding 100 kW), has four main goals. The first is to outline the elements of a siting strategy that will identify the most favorable wind energy sites in a region and that will provide sufficient wind data to make responsible economic evaluations of the site wind resource possible. The second is to critique and summarize siting techniques that were studied in the Department of Energy (DOE) Wind Energy Program. The third goal is to educate utility technical personnel, engineering consultants, and meteorological consultants (who may have not yet undertaken wind energy consulting) on meteorological phenomena relevant to wind turbine siting in order to enhance dialogues between these groups. The fourth goal is to minimize the chances of failure of early siting programs due to insufficient understanding of wind behavior.

  2. Meteorological Integration for the Biological Warning and Incident Characterization (BWIC) System: General Guidance for BWIC Cities

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, William J.; Wang, Weiguo; Rutz, Frederick C.; Chapman, Elaine G.; Rishel, Jeremy P.; Xie, YuLong; Seiple, Timothy E.; Allwine, K Jerry

    2007-02-16

    The U.S. Department of Homeland Security (DHS) is responsible for developing systems to detect the release of aerosolized bioagents in urban environments. The system that accomplishes this, known as BioWatch, is a robust first-generation monitoring system. In conjunction with the BioWatch detection network, DHS has also developed a software tool for cities to use to assist in their response when a bioagent is detected. This tool, the Biological Warning and Incident Characterization (BWIC) System, will eventually be deployed to all BioWatch cities to aid in the interpretation of the public health significance of indicators from the BioWatch networks. BWIC consists of a set of integrated modules, including meteorological models, that estimate the effect of a biological agent on a city’s population once it has been detected. For the meteorological models in BWIC to successfully calculate the distribution of biological material, they must have as input accurate meteorological data, and wind fields in particular. The purpose of this document is to provide guidance for cities to use in identifying sources of good-quality local meteorological data that BWIC needs to function properly. This process of finding sources of local meteorological data, evaluating the data quality and gaps in coverage, and getting the data into BWIC, referred to as meteorological integration, is described. The good news for many cities is that meteorological measurement networks are becoming increasingly common. Most of these networks allow their data to be distributed in real time via the internet. Thus, cities will often only need to evaluate the quality of available measurements and perhaps add a modest number of stations where coverage is poor.

  3. HARAD, Decay Isotope Concentration from Atmospheric Noble-Gas Release

    International Nuclear Information System (INIS)

    Moore, R.E.

    1986-01-01

    1 - Description of problem or function: HARAD calculates concentrations of radioactive daughters in air following the atmospheric release of a parent radionuclide for a variety of release heights and meteorological conditions. It can be applied most profitably to the assessment of doses to man from the noble gases such as Rn-222, Rn-220, and Xe and Kr isotopes. These gases can produce significant quantities of short-lived particulate daughters in an airborne plume, which are the major contributors to dose. The simultaneous processes of radioactive decay, buildup and environmental loss due to wet and dry deposition on ground surfaces are calculated for a daughter chain in an airborne plume as it is dispersed downwind from a point of release of a parent. 2 - Method of solution: The code evaluates the analytic solution to the set of coupled first order differential equations describing time variation of the concentration of a chain of radionuclides. The analytic solutions assume that the coefficient describing the fractional rate of dry deposition is constant with time. To account for the variation the time coordinate is automatically divided into intervals and a set of average values are used. 3 - Restrictions on the complexity of the problem: - The maximum length of decay chain is 10 nuclides; calculations can be made at a maximum of 24 downwind distances

  4. GASPAR-II, Radiation Exposure to Man from Air Releases of Reactor Effluents

    International Nuclear Information System (INIS)

    1993-01-01

    1 - Description of program or function: GASPAR implements the air release dose models of the NRC Regulatory Guide 1.109 for noble gases (semi-infinite plume only) and the radioiodine and particulate emissions. GASPAR computes both population (ALARA-As Low As Reasonably Achievable and NEPA-National Environmental Policy Act) and individual doses. Site data, meteorological data, radionuclide release source terms, and location meteorological data for selected individuals are specified as input data. The site data includes population data and milk, meat, and vegetation production. The meteorological data includes dispersion X/Q, X/Q decayed, X/Q decayed and depleted, and deposition. Population doses, individual doses, and cost benefit tables are calculated. 2 - Method of solution: There are two basic types of calculations, the population dose calculation and the individual dose calculation; however, both may be combined in a single GASPAR execution. There are usually several source terms corresponding to several release points. As the dose is computed for each source term it is accumulated so that the dose printed for the first source term is the actual dose for that term. For all subsequent source terms the dose printed is the accumulated dose with the dose printed for the last source term, the grand total for the problem. For the cost benefit table, individual source term doses are generated. Seven pathways by which the nuclides travel to man are considered. These are plume, ground, inhalation, vegetation, cows' milk, goats' milk, and meat. For the individual dose calculations, man is subdivided into the four age groups of infant (0 to 1 year), child (1-11 years), teenager (12-18 years) and adult (over 18 years). Each of these calculations take into account eight body organs - T. body, G.I. track, bone, liver, kidney, thyroid, lung, and skin. 3 - Restrictions on the complexity of the problem: None noted

  5. Workshop on meteorological aspects of emergency-response plans for nuclear power plants

    International Nuclear Information System (INIS)

    SethuRaman, S.; Tichler, J.; Patrinos, A.; Dabbert, W.F.; Ludwig, F.L.; Ruff, R.E.

    1982-08-01

    The workshop was organized into five short introductory technical sessions, followed by working sessions. The technical sessions provided an overview of the state of the art in health physics; release characteristics; transport, diffusion, and deposition; and operational aspects. Three working groups of approximately 15 members each met for two days to develop specific recommendations and guidance for implementation of the regulatory requirements. The three working groups addressed the themes of health physics and meteorology, release characteristics and meteorology, and dispersion and deposition. This report summarizes the activities and results of both parts of the workshop. The main body of the report is organized in three chapters: an introduction; detailed recommendations of the three working groups; and a summary of the recommendations

  6. The virion RNA species of the Kirsten murine sarcoma-leukemia virus complex released from a clonally related series of mouse cells

    International Nuclear Information System (INIS)

    Clewley, J.P.; Avery, R.J.

    1982-01-01

    We have characterized the virion RNA species of Kirsten sarcoma (KiSV) and Kirsten leukemia (KiLV) viruses released from a clonally related series of mouse cells (14). We have identified the KiLV and KiSV genome RNAs. In addition to the viral RNA species we find large amounts of a virus-like RNA (VL30 RNA), which is heterogeneous and shows variability in its expression. The amount of VL30 RNA in virions does not correlate with the state of transformation of the cells releasing the virus or the ability of the virus to transform other cells. Characterization of RNA rescued from non-producer cells has revealed a sarcoma virus (KiSVsub(SB3) with an oligonucleotide fingerprint different from that of a standard KiSV RNA, suggesting that it has lost some viral sequences. The oligonucleotide fingerprints of KiLV and VL30 RNAs are distinct from each other and from those reported for other murine leukemia virus RNAs. (Author)

  7. Meteorological influences on coastal new particle formation

    NARCIS (Netherlands)

    Leeuw, G. de; Kunz, G.J.; Buzorius, G.; O`Dowd, C.D.

    2002-01-01

    The meteorological situation at the midlatitude coastal station of Mace Head, Ireland, is described based on observations during the New Particle Formation and Fate in the Coastal Environment (PARFORCE) experiments in September 1998 and June 1999. Micrometeorological sensors were mounted near the

  8. assessment and monitoring of meteorological and hydrological ...

    African Journals Online (AJOL)

    F. Djellouli, A. Bouanani and K. Babahamed

    2016-09-01

    Sep 1, 2016 ... en meteorological drought indices was found for 9-month time step ... Drought severity is expected to increase further in the next 50 years [20]. ... In the present study, our interest to examine the applicability of various drought ...

  9. Meteorological features associated with unprecedented precipitation ...

    Indian Academy of Sciences (India)

    56

    India Meteorological Department, Lodi Road, New Delhi-110003 .... adjoining Iran & Arabian Sea with temperature gradient of order 5 Kelvin on 28th February, 2015. (Fig. 4a). On 1st .... Indian Region on 00 UTC of 1st March and seen in two patches, one over north Pakistan & .... Accordingly, the precipitation belt also.

  10. Meteorological data related to the Chernobyl accident

    International Nuclear Information System (INIS)

    Graziani, G.; Zarimpas, N.

    1989-01-01

    This report presents a detailed technical description of the JRC-Ispra comprehensive collection of meteorological information related to the Chernobyl accident and attempts an analysis of the data in order to perform an initial checking of their quality and facilitate a suitable and compact way of display

  11. Integrating meteorology into research on migration.

    Science.gov (United States)

    Shamoun-Baranes, Judy; Bouten, Willem; van Loon, E Emiel

    2010-09-01

    Atmospheric dynamics strongly influence the migration of flying organisms. They affect, among others, the onset, duration and cost of migration, migratory routes, stop-over decisions, and flight speeds en-route. Animals move through a heterogeneous environment and have to react to atmospheric dynamics at different spatial and temporal scales. Integrating meteorology into research on migration is not only challenging but it is also important, especially when trying to understand the variability of the various aspects of migratory behavior observed in nature. In this article, we give an overview of some different modeling approaches and we show how these have been incorporated into migration research. We provide a more detailed description of the development and application of two dynamic, individual-based models, one for waders and one for soaring migrants, as examples of how and why to integrate meteorology into research on migration. We use these models to help understand underlying mechanisms of individual response to atmospheric conditions en-route and to explain emergent patterns. This type of models can be used to study the impact of variability in atmospheric dynamics on migration along a migratory trajectory, between seasons and between years. We conclude by providing some basic guidelines to help researchers towards finding the right modeling approach and the meteorological data needed to integrate meteorology into their own research. © The Author 2010. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved.

  12. Atmospheric Science: It's More than Meteorology.

    Science.gov (United States)

    Smith, David R.; Krockover, Gerald H.

    1988-01-01

    Indicates that atmospheric science is not just forcasting the weather. Gives an overview of current topics in meteorology including ozone depletion, acid precipitation, winter cyclones, severe local storms, the greenhouse effect, wind shear and microbursts. Outlines the Atmospheric Sciences Education Program at Purdue University to produce…

  13. Problem-Based Learning Approaches in Meteorology

    Science.gov (United States)

    Charlton-Perez, Andrew James

    2013-01-01

    Problem-Based Learning, despite recent controversies about its effectiveness, is used extensively as a teaching method throughout higher education. In meteorology, there has been little attempt to incorporate Problem-Based Learning techniques into the curriculum. Motivated by a desire to enhance the reflective engagement of students within a…

  14. How To...Activities in Meteorology.

    Science.gov (United States)

    Nimmer, Donald N.; Sagness, Richard L.

    This series of experiments seeks to provide laboratory exercises which demonstrate concepts in Earth Science, particularly meteorology. Materials used in the experiments are easily obtainable. Examples of experiments include: (1) making a thermometer; (2) air/space relationship; (3) weight of air; (4) barometers; (5) particulates; (6) evaporation;…

  15. assessment and monitoring of meteorological and hydrological ...

    African Journals Online (AJOL)

    During the last century, Algeria experienced a rainfall deficit was recorded in 1944, then successive drought periods since 1975 to the present day in Northen and Eastern. The most recent has repercussions on water resources and on agriculture. In this paper, we focus on the meteorological and hydrological drought.

  16. Meteorological Development Laboratory Student Career Experience Program

    Science.gov (United States)

    McCalla, C., Sr.

    2007-12-01

    The National Oceanic and Atmospheric Administration's (NOAA) National Weather Service (NWS) provides weather, hydrologic, and climate forecasts and warnings for the protection of life and property and the enhancement of the national economy. The NWS's Meteorological Development Laboratory (MDL) supports this mission by developing meteorological prediction methods. Given this mission, NOAA, NWS, and MDL all have a need to continually recruit talented scientists. One avenue for recruiting such talented scientist is the Student Career Experience Program (SCEP). Through SCEP, MDL offers undergraduate and graduate students majoring in meteorology, computer science, mathematics, oceanography, physics, and statistics the opportunity to alternate full-time paid employment with periods of full-time study. Using SCEP as a recruiting vehicle, MDL has employed students who possess some of the very latest technical skills and knowledge needed to make meaningful contributions to projects within the lab. MDL has recently expanded its use of SCEP and has increased the number of students (sometimes called co- ops) in its program. As a co-op, a student can expect to develop and implement computer based scientific techniques, participate in the development of statistical algorithms, assist in the analysis of meteorological data, and verify forecasts. This presentation will focus on describing recruitment, projects, and the application process related to MDL's SCEP. In addition, this presentation will also briefly explore the career paths of students who successfully completed the program.

  17. NASA's aviation safety - meteorology research programs

    Science.gov (United States)

    Winblade, R. L.

    1983-01-01

    The areas covering the meteorological hazards program are: severe storms and the hazards to flight generated by severe storms; clear air turbulence; icing; warm fog dissipation; and landing systems. Remote sensing of ozone by satellites, and the use of satellites as data relays is also discussed.

  18. A meteorological distribution system for high-resolution terrestrial modeling (MicroMet)

    Science.gov (United States)

    Glen E. Liston; Kelly Elder

    2006-01-01

    An intermediate-complexity, quasi-physically based, meteorological model (MicroMet) has been developed to produce high-resolution (e.g., 30-m to 1-km horizontal grid increment) atmospheric forcings required to run spatially distributed terrestrial models over a wide variety of landscapes. The following eight variables, required to run most terrestrial models, are...

  19. Meteorology and climatology as parameters on low level waste disposal monitoring

    International Nuclear Information System (INIS)

    Culkowski, W.M.

    1982-01-01

    Once a site has been chosen for the burial of low level wastes, meteorological input is required in two forms, as climatology and as an estimator of airborne concentrations. The climatological data are fundamental to assessing hydrologic flow which may transport waste material from the original site. Airborne nuclear activity may occur by accidental release of material during the active burial phase or may result from gas formation in the trenches over a period of years

  20. Priority of a Hesitant Fuzzy Linguistic Preference Relation with a Normal Distribution in Meteorological Disaster Risk Assessment.

    Science.gov (United States)

    Wang, Lihong; Gong, Zaiwu

    2017-10-10

    As meteorological disaster systems are large complex systems, disaster reduction programs must be based on risk analysis. Consequently, judgment by an expert based on his or her experience (also known as qualitative evaluation) is an important link in meteorological disaster risk assessment. In some complex and non-procedural meteorological disaster risk assessments, a hesitant fuzzy linguistic preference relation (HFLPR) is often used to deal with a situation in which experts may be hesitant while providing preference information of a pairwise comparison of alternatives, that is, the degree of preference of one alternative over another. This study explores hesitation from the perspective of statistical distributions, and obtains an optimal ranking of an HFLPR based on chance-restricted programming, which provides a new approach for hesitant fuzzy optimisation of decision-making in meteorological disaster risk assessments.

  1. Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry

    DEFF Research Database (Denmark)

    Müller, Margit S; Obel, Linea Lykke Frimodt; Waagepetersen, Helle S

    2013-01-01

    The polyether antibiotic ionomycin is a common research tool employed to raise cytosolic Ca(2+) in almost any cell type. Although initially thought to directly cause physicochemical translocation of extracellular Ca(2+) into the cytosol, a number of studies have demonstrated that the mechanism of......(2+), consisting of an initial peak and a subsequent sustained plateau. The response was dependent on concentration and exposure time. While the plateau phase was abolished in the absence of extracellular Ca(2+), the peak phase persisted. The peak amplitude could be lowered significantly...... by application of dantrolene, demonstrating involvement of Ca(2+)-induced Ca(2+)-release (CICR). The plateau phase was markedly reduced when store-operated Ca(2+)-entry (SOCE) was blocked with 2-aminoethoxydiphenyl borate. Our results show that ionomycin directly affects internal Ca(2+) stores in astrocytes...

  2. Model variations in predicting incidence of Plasmodium falciparum malaria using 1998-2007 morbidity and meteorological data from south Ethiopia

    OpenAIRE

    Loha, Eskindir; Lindtj?rn, Bernt

    2010-01-01

    Abstract Background Malaria transmission is complex and is believed to be associated with local climate changes. However, simple attempts to extrapolate malaria incidence rates from averaged regional meteorological conditions have proven unsuccessful. Therefore, the objective of this study was to determine if variations in specific meteorological factors are able to consistently predict P. falciparum malaria incidence at different locations in south Ethiopia. Methods Retrospective data from 4...

  3. Comparison of HYSPLIT-4 model simulations of the ETEX data, using meteorological input data of differing spatial and temporal resolution

    International Nuclear Information System (INIS)

    Hess, G.D.; Mills, G.A.; Draxler, R.R.

    1997-01-01

    Model simulations of air concentrations during ETEX-1 using the HYSPLIT-4 (HYbrid Single-Particle Lagrangian Integrated Trajectories, version 4) code and analysed meteorological data fields provided by ECMWF and the Australian Bureau of Meteorology are presented here. The HYSPLIT-4 model is a complete system for computing simple trajectories to complex dispersion and deposition simulations using either puff or particle approaches. A mixed dispersion algorithm is employed in this study: puffs in the horizontal and particles in the vertical

  4. The role of seasonal, climatic and meteorological conditions in modifying nuclear accident consequences

    International Nuclear Information System (INIS)

    Mueller, H.; Proehl, G.

    1989-01-01

    One of the most important factors which influence the ingestion doses after an accidental release of radionuclides is the season of the year at which the release occurs. This is demonstrated with some examples for German conditions. This seasonal effect depends strongly on the growing periods of the different plants. Therefore it is influenced by the climatic conditions which vary to a large degree in the different countries causing very different growing periods. The influence of the meteorological conditions during and after the passing of a radioactive cloud on the initial contamination of the plants is discussed

  5. ICON - Port Everglades 2015 Meteorological Observations (NCEI Accession 0156578)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  6. Research Ship Oceanus Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Oceanus Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  7. NOAA Ship Okeanos Explorer Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Okeanos Explorer Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System...

  8. Research Ship Melville Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Melville Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  9. Research Ship Atlantic Explorer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Atlantic Explorer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  10. NOAA Ship Nancy Foster Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Nancy Foster Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  11. Research Ship Healy Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Healy Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  12. Research Ship Knorr Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Knorr Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  13. Research Ship Nathaniel B. Palmer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Nathaniel B. Palmer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  14. NOAA Ship Delaware II Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Delaware II Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  15. Research Ship Atlantis Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Atlantis Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  16. NOAA Ship Pisces Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Pisces Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  17. Research Ship Robert Gordon Sproul Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Robert Gordon Sproul Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  18. Research Ship Roger Revelle Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Roger Revelle Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  19. NOAA Ship Fairweather Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Fairweather Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  20. NOAA Ship Bell M. Shimada Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Bell M. Shimada Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  1. NOAA Ship Hi'ialakai Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Hi'ialakai Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  2. Research Ship New Horizon Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship New Horizon Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  3. NOAA Ship Ronald Brown Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Ronald Brown Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  4. Research Ship Aurora Australis Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Aurora Australis Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  5. NOAA Ship Miller Freeman Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Miller Freeman Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  6. NOAA Ship David Starr Jordan Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship David Starr Jordan Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  7. NOAA Ship Gordon Gunter Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Gordon Gunter Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  8. NOAA Ship Henry B. Bigelow Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Henry B. Bigelow Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  9. NOAA Ship Oregon II Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oregon II Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  10. NOAA Ship Oscar Dyson Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oscar Dyson Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  11. NOAA Ship Oscar Elton Sette Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oscar Elton Sette Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  12. NOAA Ship Fairweather Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Fairweather Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  13. Research Ship Kilo Moana Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Kilo Moana Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  14. NOAA Ship Nancy Foster Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Nancy Foster Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  15. NOAA Ship Gordon Gunter Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Gordon Gunter Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  16. Research Ship Southern Surveyor Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Southern Surveyor Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  17. NOAA Ship Rainier Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Rainier Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  18. Research Ship Tangaroa Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Tangaroa Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  19. NOAA Ship Ka'imimoana Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Ka'imimoana Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  20. NOAA Ship Oregon II Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oregon II Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  1. ICON - Media Luna Reef 2009 Meteorological and Oceanographic Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  2. NOAA Ship Rainier Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Rainier Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  3. NOAA Ship Pisces Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Pisces Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  4. ICON - Port Everglades 2014 Meteorological Observations (NCEI Accession 0137094)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  5. ICON - Salt River Bay 2010 Meteorological and Oceanographic Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  6. ICON - Port Everglades 2013 Meteorological Observations (NODC Accession 0124002)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  7. ICON - Little Cayman, Cayman Islands 2009 Meteorological and Oceanographic Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  8. ICON - Salt River Bay 2009 Meteorological and Oceanographic Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  9. Research Ship T. G. Thompson Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship T. G. Thompson Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  10. Research Ship Laurence M. Gould Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Laurence M. Gould Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  11. NOAA Ship Ronald Brown Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Ronald Brown Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  12. NOAA Ship Okeanos Explorer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Okeanos Explorer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  13. NOAA Ship Oscar Dyson Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oscar Dyson Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  14. ICON - Port Everglades 2012 Meteorological Observations (NODC Accession 0117727)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  15. Instrumentation for high-frequency meteorological observations from research vessel

    Digital Repository Service at National Institute of Oceanography (India)

    VijayKumar, K.; Khalap, S.; Mehra, P.

    Ship provides an attractive platform from which high-frequency meteorological observations (e.g., wind components, water vapor density, and air temperature) can be made accurately. However, accurate observations of meteorological variables depend...

  16. ICON - Salt River Bay 2005 Meteorological and Oceanographic Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  17. Frequency modulator. Transmission of meteorological signals in LVC

    International Nuclear Information System (INIS)

    Rivero G, P.T.; Ramirez S, R.; Gonzalez M, J.L.; Rojas N, P.; Celis del Angel, L.

    2007-01-01

    The development of the frequency modulator and demodulator circuit for transmission of meteorological signals by means of fiber optics of the meteorology station to the nuclear reactor unit 1 in the Laguna Verde Central in Veracruz is described. (Author)

  18. ICON - North Norman's Patch Reef 2004 Meteorological and Oceanographic Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Atlantic Oceanographic and Meteorological Laboratory (AOML) of OAR is conducting research on the influence of meteorological and oceanographic factors upon coral...

  19. Use of data assimilation procedures in the meteorological pre-processors of decision support systems to improve the meteorological input of atmospheric dispersion models

    International Nuclear Information System (INIS)

    Kovalets, I.; Andronopoulos, S.; Bartzis, J.G.

    2003-01-01

    Full text: The Atmospheric Dispersion Models (ADMs) play a key role in decision support systems for nuclear emergency management, as they are used to determine the current, and predict the future spatial distribution of radionuclides after an accidental release of radioactivity to the atmosphere. Meteorological pre-processors (MPPs), usually act as interface between the ADMs and the incoming meteorological data. Therefore the quality of the results of the ADMs crucially depends on the input that they receive from the MPPs. The meteorological data are measurements from one or more stations in the vicinity of the nuclear power plant and/or prognostic data from Numerical Weather Prediction (NWP) models of National Weather Services. The measurements are representative of the past and current local conditions, while the NWP data cover a wider range in space and future time, where no measurements exist. In this respect, the simultaneous use of both by an MPP immediately poses the questions of consistency and of the appropriate methodology for reconciliation of the two kinds of meteorological data. The main objective of the work presented in this paper is the introduction of data assimilation (DA) techniques in the MPP of the RODOS (Real-time On-line Decision Support) system for nuclear emergency management in Europe, developed under the European Project 'RODOS-Migration', to reconcile the NWP data with the local observations coming from the meteorological stations. More specifically, in this paper: the methodological approach for simultaneous use of both meteorological measurements and NWP data in the MPP is presented; the method is validated by comparing results of calculations with experimental data; future ways of improvement of the meteorological input for the calculations of the atmospheric dispersion in the RODOS system are discussed. The methodological approach for solving the DA problem developed in this work is based on the method of optimal interpolation (OI

  20. PM10 Pollution: Its Prediction and Meteorological Influence in PasirGudang, Johor

    International Nuclear Information System (INIS)

    Afzali, A; Ramli, M; Rashid, M; Sabariah, B

    2014-01-01

    Ambient PM 10 (i.e particulate diameter less than 10 um in size) pollution has negative impacts on human health and it is influenced by meteorological conditions. Although the correlation between meteorological parameters and PM 10 concentrations is significant in most cases, the linear relationship between them implies that the fraction of the variance, R2 rarely exceeds 25%. However, considering the previous day's concentration of pollutants to the multi-linear regression enhances the model performance and increases the value of R2. Alternatively, artificial neural networks (ANN) are used to capture the complex relationships among many factors considered which present a better prediction. Thus, this study presents the results of predicting ambient PM 10 concentration and the influence of meteorological parameters based on the data sampled from 2008 – 2010 in an industrial area of PasirGudang, Johor

  1. Meteorological services annual data report for 2015

    Energy Technology Data Exchange (ETDEWEB)

    Heiser, John [Brookhaven National Lab. (BNL), Upton, NY (United States); Smith, Scott [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-01-25

    This document presents the meteorological data collected at Brookhaven National Laboratory (BNL) by Meteorological Services (Met Services) for the calendar year 2015. The purpose is to publicize the data sets available to emergency personnel, researchers and facility operations. Met services has been collecting data at BNL since 1949. Data from 1994 to the present is available in digital format. Data is presented in monthly plots of one-minute data. This allows the reader the ability to peruse the data for trends or anomalies that may be of interest to them. Full data sets are available to BNL personnel and to a limited degree outside researchers. The full data sets allow plotting the data on expanded time scales to obtain greater details (e.g., daily solar variability, inversions, etc.).

  2. Meteorological services annual data report for 2016

    Energy Technology Data Exchange (ETDEWEB)

    Heiser, John [Brookhaven National Lab. (BNL), Upton, NY (United States); Smith, S.

    2017-01-18

    This document presents the meteorological data collected at Brookhaven National Laboratory (BNL) by Meteorological Services (Met Services) for the calendar year 2016. The purpose is to publicize the data sets available to emergency personnel, researchers and facility operations. Met services has been collecting data at BNL since 1949. Data from 1994 to the present is available in digital format. Data is presented in monthly plots of one-minute data. This allows the reader the ability to peruse the data for trends or anomalies that may be of interest to them. Full data sets are available to BNL personnel and to a limited degree outside researchers. The full data sets allow plotting the data on expanded time scales to obtain greater details (e.g., daily solar variability, inversions, etc.).

  3. Meteorological Automatic Weather Station (MAWS) Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Holdridge, Donna J [Argonne National Lab. (ANL), Argonne, IL (United States); Kyrouac, Jenni A [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-08-01

    The Meteorological Automatic Weather Station (MAWS) is a surface meteorological station, manufactured by Vaisala, Inc., dedicated to the balloon-borne sounding system (BBSS), providing surface measurements of the thermodynamic state of the atmosphere and the wind speed and direction for each radiosonde profile. These data are automatically provided to the BBSS during the launch procedure and included in the radiosonde profile as the surface measurements of record for the sounding. The MAWS core set of measurements is: Barometric Pressure (hPa), Temperature (°C), Relative Humidity (%), Arithmetic-Averaged Wind Speed (m/s), and Vector-Averaged Wind Direction (deg). The sensors that collect the core variables are mounted at the standard heights defined for each variable.

  4. Meteorological observatory for Antarctic data collection

    International Nuclear Information System (INIS)

    Grigioni, P.; De Silvestri, L.

    1996-01-01

    In the last years, a great number of automatic weather stations was installed in Antarctica, with the aim to examine closely the weather and climate of this region and to improve the coverage of measuring points on the Antarctic surface. In 1987 the Italian Antarctic Project started to set up a meteorological network, in an area not completely covered by other countries. Some of the activities performed by the meteorological observatory, concerning technical functions such as maintenance of the AWS's and the execution of radio soundings, or relating to scientific purposes such as validation and elaboration of collected data, are exposed. Finally, some climatological considerations on the thermal behaviour of the Antarctic troposphere such as 'coreless winter', and on the wind field, including katabatic flows in North Victoria Land are described

  5. Meteorological services annual data report for 2017

    Energy Technology Data Exchange (ETDEWEB)

    Heiser, John

    2018-01-18

    This document presents the meteorological data collected at Brookhaven National Laboratory (BNL) by Meteorological Services (Met Services) for the calendar year 2017. The purpose is to publicize the data sets available to emergency personnel, researchers and facility operations. Met services has been collecting data at BNL since 1949. Data from 1994 to the present is available in digital format. Data is presented in monthly plots of one-minute data. This allows the reader the ability to peruse the data for trends or anomalies that may be of interest to them. Full data sets are available to BNL personnel and to a limited degree outside researchers. The full data sets allow plotting the data on expanded time scales to obtain greater details (e.g., daily solar variability, inversions, etc.).

  6. Autonomous Aerial Sensors for Wind Power Meteorology

    DEFF Research Database (Denmark)

    Giebel, Gregor; Schmidt Paulsen, Uwe; Reuder, Joachim

    2011-01-01

    , UAVs could be quite cost-effective. In order to test this assumption and to test the limits of UAVs for wind power meteorology, this project assembles four different UAVs from four participating groups. Risø has built a lighter-than-air kite with a long tether, Bergen University flies a derivative......This paper describes a new approach for measurements in wind power meteorology using small unmanned flying platforms. Large-scale wind farms, especially offshore, need an optimisation between installed wind power density and the losses in the wind farm due to wake effects between the turbines. Good...... movement. In any case, a good LIDAR or SODAR will cost many tenthousands of euros. Another current problem in wind energy is the coming generation of wind turbines in the 10-12MW class, with tip heights of over 200m. Very few measurement masts exist to verify our knowledge of atmospheric physics, and most...

  7. Uncertainty in dispersion forecasts using meteorological ensembles

    International Nuclear Information System (INIS)

    Chin, H N; Leach, M J

    1999-01-01

    The usefulness of dispersion forecasts depends on proper interpretation of results. Understanding the uncertainty in model predictions and the range of possible outcomes is critical for determining the optimal course of action in response to terrorist attacks. One of the objectives for the Modeling and Prediction initiative is creating tools for emergency planning for special events such as the upcoming the Olympics. Meteorological forecasts hours to days in advance are used to estimate the dispersion at the time of the event. However, there is uncertainty in any meteorological forecast, arising from both errors in the data (both initial conditions and boundary conditions) and from errors in the model. We use ensemble forecasts to estimate the uncertainty in the forecasts and the range of possible outcomes

  8. RAVEN Beta Release

    International Nuclear Information System (INIS)

    Rabiti, Cristian; Alfonsi, Andrea; Cogliati, Joshua Joseph; Mandelli, Diego; Kinoshita, Robert Arthur; Wang, Congjian; Maljovec, Daniel Patrick; Talbot, Paul William

    2016-01-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  9. RAVEN Beta Release

    Energy Technology Data Exchange (ETDEWEB)

    Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Alfonsi, Andrea [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cogliati, Joshua Joseph [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kinoshita, Robert Arthur [Idaho National Lab. (INL), Idaho Falls, ID (United States); Wang, Congjian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Maljovec, Daniel Patrick [Idaho National Lab. (INL), Idaho Falls, ID (United States); Talbot, Paul William [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-02-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  10. Method to characterize local meteorology at nuclear facilities for application to emergency response needs

    International Nuclear Information System (INIS)

    Lindsey, C.G.; Glantz, C.S.

    1986-04-01

    Effluent dispersion is evaluated using computer codes that require various meteorological parameters such as wind and stability data. These data will be based on current conditions at the site in question, and on forecasts of the expected local meteorology for the time period to be simulated. To assist NRC personnel in preparing these forecasts, a weather-typing model was implemented to analyze the characteristic behavior of local meteorology as it responds to various synoptic-scale weather features (e.g., warm fronts, cold fronts, high pressure systems). Historical observations acquired by instrumented towers at several nuclear power plants were analyzed as a function of the prevailing synoptic weather feature, synoptic-scale pressure gradient, and time of year. This study focused on sites located in shoreline and complex terrain environments because of the occurrence of mesoscale circulations, which are the sea/lake-land breeze and valley wind systems. Such circulations produce diurnally changing wind and stability conditions that cannot be readily identified by synoptic-scale weather forecasts. The advantage in analyzing the climatological behavior of local meteorology as it responds to various synoptic weather systems is that certain weather systems will control the local meteorology and produce persistent conditions

  11. Integrating Current Meteorological Research Through Club Fundraising

    Science.gov (United States)

    Gill, S. S.; Kauffman, C. M.

    2003-12-01

    Earth science programs whose focus is primarily an undergraduate education do not often have the funding to take students to very many conferences which could expose the student to new research as well as possible graduate programs and employment opportunities. Conferences also give the more enthusiastic and hardworking students a venue in which to present their research to the meteorological community. In addition, the California University services largely lower income counties, which make student attendance at conferences even more difficult even though the student in SW PA may be individually motivated. This issue is compounded by the fact that the Meteorology Concentration within the Earth Science department at Cal U is composed of only two full-time Professors, which limits the amount of research students can be exposed to within a classroom setting. New research ideas presented at conferences are thus an important mechanism for broadening what could be an isolated program. One way in which the meteorology program has circumvented the funding problem to a certain extent is through an active student club. With nearly 60 majors (3/4 of which are active in club activities, the meteorology club is able to execute a variety of fundraising activities. Money that is raised can then request from student services matching funds. Further money is given to clubs, which are very active not only in fundraising, but using that money for academic related activities. For the last 3 years the club budget has been in the neighborhood of \\$4500. The money has then been used to partially finance student registration and accommodation costs making conference attendance much more affordable. Normally 8-16 students attend conferences that they would otherwise not be able to attend without great expense. There are times when more than 16 students wish to attend, but travel arrangements prohibit more than 16. Moreover club money is also use to supplement student costs on a summer

  12. Uncertainty analysis of hydro-meteorological forecasts

    OpenAIRE

    Grythe, Karl Kristian; Gao, Yukun

    2010-01-01

    Masteroppgave i informasjons- og kommunikasjonsteknologi 2010 – Universitetet i Agder, Grimstad Meteorological and hydrological forecasts are very important to human’s life which concerns agriculture, industry, transport, etc. The Nordic hydropower industry use and develop hydrological forecasting models to make predictions of rivers steam flow. The quantity of incoming stream flow is important to the electricity production because excessive water in reservoir will cause flood ...

  13. Naval Meteorology and Oceanography Command exhibit entrance

    Science.gov (United States)

    2000-01-01

    StenniSphere at NASA's John C. Stennis Space Center in Hancock County, Miss., invites visitors to discover why America comes to Stennis Space Center before going into space. Designed to entertain while educating, StenniSphere includes informative displays and exhibits from NASA and other agencies located at Stennis, such as this one from the Naval Meteorology and Oceanography Command. Visitors can 'travel' three-dimensionally under the sea and check on the weather back home in the Weather Center.

  14. Naval Meteorology and Oceanography Command exhibit

    Science.gov (United States)

    2000-01-01

    Designed to entertain while educating, StenniSphere at the John C. Stennis Space Center in Hancock County, Miss., includes informative displays and exhibits from NASA and other agencies located at Stennis, such as this one from the Naval Meteorology and Oceanography Command. Visitors can 'travel' three-dimensionally under the sea and check on the weather back home in the Weather Center. StenniSphere is open free of charge from 9 a.m. to 5 p.m. daily.

  15. Computer code to assess accidental pollutant releases

    International Nuclear Information System (INIS)

    Pendergast, M.M.; Huang, J.C.

    1980-07-01

    A computer code was developed to calculate the cumulative frequency distributions of relative concentrations of an air pollutant following an accidental release from a stack or from a building penetration such as a vent. The calculations of relative concentration are based on the Gaussian plume equations. The meteorological data used for the calculation are in the form of joint frequency distributions of wind and atmospheric stability

  16. Reliability analysis of meteorological data registered during nuclear power plant normal operation

    International Nuclear Information System (INIS)

    Amado, V.; Ulke, A.; Marino, B.; Thomas, L.

    2011-01-01

    The atmosphere is the environment in which gaseous radioactive discharges from nuclear power plants are transported. It is therefore essential to have reliable meteorological information to characterize the dispersion and feed evaluation models and radiological environmental impact during normal operation of the plant as well as accidental releases. In this way it is possible to determine the effects on the environment and in humans. The basic data needed to represent adequately the local weather include air temperature, wind speed and direction, rainfall, humidity and pressure. On the other hand, specific data consistent with the used model is required to determine the turbulence, for instance, radiation, cloud cover and vertical temperature gradient. It is important that the recorded data are representative of the local meteorology. This requires, first, properly placed instruments, that should be kept in operation and undergoing maintenance on a regular basis. Second, but equally substantial, a thorough analysis of its reliability must be performed prior to storage and/or data processing. In this paper we present the main criteria to consider choosing the location of a meteorological tower in the area of a nuclear power plant and propose a methodology for assessing the reliability of recorded data. The methodology was developed from the analysis of meteorological data registered in nuclear power plants in Argentina. (authors) [es

  17. Dispersion modeling of accidental releases of toxic gases - utility for the fire brigades.

    Science.gov (United States)

    Stenzel, S.; Baumann-Stanzer, K.

    2009-09-01

    Several air dispersion models are available for prediction and simulation of the hazard areas associated with accidental releases of toxic gases. The most model packages (commercial or free of charge) include a chemical database, an intuitive graphical user interface (GUI) and automated graphical output for effective presentation of results. The models are designed especially for analyzing different accidental toxic release scenarios ("worst-case scenarios”), preparing emergency response plans and optimal countermeasures as well as for real-time risk assessment and management. The research project RETOMOD (reference scenarios calculations for toxic gas releases - model systems and their utility for the fire brigade) was conducted by the Central Institute for Meteorology and Geodynamics (ZAMG) in cooperation with the Viennese fire brigade, OMV Refining & Marketing GmbH and Synex Ries & Greßlehner GmbH. RETOMOD was funded by the KIRAS safety research program of the Austrian Ministry of Transport, Innovation and Technology (www.kiras.at). The main tasks of this project were 1. Sensitivity study and optimization of the meteorological input for modeling of the hazard areas (human exposure) during the accidental toxic releases. 2. Comparison of several model packages (based on reference scenarios) in order to estimate the utility for the fire brigades. For the purpose of our study the following models were tested and compared: ALOHA (Areal Location of Hazardous atmosphere, EPA), MEMPLEX (Keudel av-Technik GmbH), Trace (Safer System), Breeze (Trinity Consulting), SAM (Engineering office Lohmeyer). A set of reference scenarios for Chlorine, Ammoniac, Butane and Petrol were proceed, with the models above, in order to predict and estimate the human exposure during the event. Furthermore, the application of the observation-based analysis and forecasting system INCA, developed in the Central Institute for Meteorology and Geodynamics (ZAMG) in case of toxic release was

  18. Transport of breeder reactor-fire-generated sodium oxide aerosols for building-wake-dominated meteorology

    Energy Technology Data Exchange (ETDEWEB)

    Fields, D.E.; Cooper, A.C.; Miller, C.W.

    1987-02-01

    This report describes the methodology used and results obtained in efforts to estimate the sodium aerosol concentrations at air intake ports of a liquid-metal cooled, fast-breeder nuclear reactor. An earlier version of this methodology has been previously discussed (Fields and Miller, 1985). A range of wind speeds from 2 to 10 m/s is assumed, and an effort is made to include building wake effects which, in many cases, dominate the dispersal of aerosols near buildings. For relatively small release rates, on the order of 1 to 10 kg/s, the plume rise is small and estimates of aerosol concentrations are derived using the methodology of Wilson and Britter (1982), which describes releases from surface vents. For release rates on the order of 100 kg/s much higher release velocities are expected, and plume rise is considered. An effective increase in release height is computed using the Split-H methodology with a parameterization suggested by Ramsdell (1983), and the release source strength is transformed to rooftop level. Evaluation of the acute release aerosol concentration is then based on the methodology for releases from a surface release of this transformed source strength. For a horizontal release, a methodology is developed to chart the plume path as a function of release and site meteorology parameters. Results described herein must be regarded as maximum aerosol concentrations, based on models derived from generic wind tunnel studies. More accurate and site-specific results may be obtained through wind tunnel simulations and through simulating emissions from release points other than those assumed here.

  19. Investigations of the uptake of transuranic radionuclides by humic and fulvic acids chemically immobilized on silica gel and their competitive release by complexing agents

    International Nuclear Information System (INIS)

    Bulman, R.A.; Szabo, G.; Clayton, R.F.; Clayton, C.R.

    1998-01-01

    The chemistry of the interactions of transuranic elements (TUs) with humic substances needs to be understood so that humate-mediated movement of transuranic radionuclides through the environment can be predicted. This paper reports the chemical immobilization on silica gel of humic and fulvic acids and evaluates the potential of these new materials for the retention of Pu and Am. In addition to the preparation of the foregoing immobilized humic substances, other low molecular weight metal-binding ligands have also been immobilized on silica gel to investigate the binding sites for transuranic elements (TUs) in humic substances. The X-ray photoelectron spectra (XPS) of Th(IV) complexed by humic acid and the immobilized humic acid are similar thus it appears that immobilization of humic acid does not generate any configurational changes in the Th(IV)-binding sites of the macromolecule. A variety of chelating agents partly mobilize these TUs sorbed on the solid phases. A batch method was used to determine the distribution coefficients (R d ) of Pu and Am between the silica gels and aqueous solutions of phosphate and citrate. The effects of the immobilized ligands, the anions and pH in the solution on sorption were assessed. Distributed coefficients (R d ) for the uptake of Pu and Am by these prepared solid phases are, in some cases, of a similar order of magnitude as those determined for soil and particles suspended in terrestrial surface waters

  20. Methane release

    International Nuclear Information System (INIS)

    Seifert, M.

    1999-01-01

    The Swiss Gas Industry has carried out a systematic, technical estimate of methane release from the complete supply chain from production to consumption for the years 1992/1993. The result of this survey provided a conservative value, amounting to 0.9% of the Swiss domestic output. A continuation of the study taking into account new findings with regard to emission factors and the effect of the climate is now available, which provides a value of 0.8% for the target year of 1996. These results show that the renovation of the network has brought about lower losses in the local gas supplies, particularly for the grey cast iron pipelines. (author)

  1. Autonomous Operation of Mars Meteorological Network

    Science.gov (United States)

    Schmidt, W.; Harri, A.-M.; Vázquez, L.; Linkin, V.; Alexashkin, S.

    2012-09-01

    In the next years a series of small landing vehicles concentrating on Martian meteorology should be deployed to the surface of Mars. As commanding from Earth will not be possible most of the time, the station software has to be capable of adapting to any foreseeable conditions and optimize the science return as much as feasible. In this paper we outline the constraints and strategies implemented into the control system of the MetNet Landers. For details to the mission and its instruments see the mission home page [1].

  2. Defense meteorological satellite measurements of total ozone

    International Nuclear Information System (INIS)

    Lovill, J.E.; Ellis, J.S.; Luther, F.M.; Sullivan, R.J.; Weichel, R.L.

    1992-01-01

    A multichannel filter radiometer (MFR) on Defense Meteorological Satellites (DMS) that measured total ozone on a global-scale from March 1977 - February 1980 is described. The total ozone data measured by the MFR were compared with total ozone data taken by surfaced-based Dobson spectrophotometers. When comparisons were made for five months, the Dobson spectrophotometer measured 2-5% more total ozone than the MFR. Comparisons between the Dobson spectrophotometer and the MFR showed a reduced RMS difference as the comparisons were made at closer proximity. A Northern Hemisphere total ozone distribution obtained from MFR data is presented

  3. Improvement of Disease Prediction and Modeling through the Use of Meteorological Ensembles: Human Plague in Uganda

    Science.gov (United States)

    Moore, Sean M.; Monaghan, Andrew; Griffith, Kevin S.; Apangu, Titus; Mead, Paul S.; Eisen, Rebecca J.

    2012-01-01

    Climate and weather influence the occurrence, distribution, and incidence of infectious diseases, particularly those caused by vector-borne or zoonotic pathogens. Thus, models based on meteorological data have helped predict when and where human cases are most likely to occur. Such knowledge aids in targeting limited prevention and control resources and may ultimately reduce the burden of diseases. Paradoxically, localities where such models could yield the greatest benefits, such as tropical regions where morbidity and mortality caused by vector-borne diseases is greatest, often lack high-quality in situ local meteorological data. Satellite- and model-based gridded climate datasets can be used to approximate local meteorological conditions in data-sparse regions, however their accuracy varies. Here we investigate how the selection of a particular dataset can influence the outcomes of disease forecasting models. Our model system focuses on plague (Yersinia pestis infection) in the West Nile region of Uganda. The majority of recent human cases have been reported from East Africa and Madagascar, where meteorological observations are sparse and topography yields complex weather patterns. Using an ensemble of meteorological datasets and model-averaging techniques we find that the number of suspected cases in the West Nile region was negatively associated with dry season rainfall (December-February) and positively with rainfall prior to the plague season. We demonstrate that ensembles of available meteorological datasets can be used to quantify climatic uncertainty and minimize its impacts on infectious disease models. These methods are particularly valuable in regions with sparse observational networks and high morbidity and mortality from vector-borne diseases. PMID:23024750

  4. Improvement of disease prediction and modeling through the use of meteorological ensembles: human plague in Uganda.

    Directory of Open Access Journals (Sweden)

    Sean M Moore

    Full Text Available Climate and weather influence the occurrence, distribution, and incidence of infectious diseases, particularly those caused by vector-borne or zoonotic pathogens. Thus, models based on meteorological data have helped predict when and where human cases are most likely to occur. Such knowledge aids in targeting limited prevention and control resources and may ultimately reduce the burden of diseases. Paradoxically, localities where such models could yield the greatest benefits, such as tropical regions where morbidity and mortality caused by vector-borne diseases is greatest, often lack high-quality in situ local meteorological data. Satellite- and model-based gridded climate datasets can be used to approximate local meteorological conditions in data-sparse regions, however their accuracy varies. Here we investigate how the selection of a particular dataset can influence the outcomes of disease forecasting models. Our model system focuses on plague (Yersinia pestis infection in the West Nile region of Uganda. The majority of recent human cases have been reported from East Africa and Madagascar, where meteorological observations are sparse and topography yields complex weather patterns. Using an ensemble of meteorological datasets and model-averaging techniques we find that the number of suspected cases in the West Nile region was negatively associated with dry season rainfall (December-February and positively with rainfall prior to the plague season. We demonstrate that ensembles of available meteorological datasets can be used to quantify climatic uncertainty and minimize its impacts on infectious disease models. These methods are particularly valuable in regions with sparse observational networks and high morbidity and mortality from vector-borne diseases.

  5. The scaffold protein calcium/calmodulin-dependent serine protein kinase controls ATP release in sensory ganglia upon P2X3 receptor activation and is part of an ATP keeper complex.

    Science.gov (United States)

    Bele, Tanja; Fabbretti, Elsa

    2016-08-01

    P2X3 receptors, gated by extracellular ATP, are expressed by sensory neurons and are involved in peripheral nociception and pain sensitization. The ability of P2X3 receptors to transduce extracellular stimuli into neuronal signals critically depends on the dynamic molecular partnership with the calcium/calmodulin-dependent serine protein kinase (CASK). The present work used trigeminal sensory neurons to study the impact that activation of P2X3 receptors (evoked by the agonist α,β-meATP) has on the release of endogenous ATP and how CASK modulates this phenomenon. P2X3 receptor function was followed by ATP efflux via Pannexin1 (Panx1) hemichannels, a mechanism that was blocked by the P2X3 receptor antagonist A-317491, and by P2X3 silencing. ATP efflux was enhanced by nerve growth factor, a treatment known to potentiate P2X3 receptor function. Basal ATP efflux was not controlled by CASK, and carbenoxolone or Pannexin silencing reduced ATP release upon P2X3 receptor function. CASK-controlled ATP efflux followed P2X3 receptor activity, but not depolarization-evoked ATP release. Molecular biology experiments showed that CASK was essential for the transactivation of Panx1 upon P2X3 receptor activation. These data suggest that P2X3 receptor function controls a new type of feed-forward purinergic signaling on surrounding cells, with consequences at peripheral and spinal cord level. Thus, P2X3 receptor-mediated ATP efflux may be considered for the future development of pharmacological strategies aimed at containing neuronal sensitization. P2X3 receptors are involved in sensory transduction and associate to CASK. We have studied in primary sensory neurons the molecular mechanisms downstream P2X3 receptor activation, namely ATP release and partnership with CASK or Panx1. Our data suggest that CASK and P2X3 receptors are part of an ATP keeper complex, with important feed-forward consequences at peripheral and central level. © 2016 International Society for Neurochemistry.

  6. Real time quality control of meteorological data used in SRP's emergency response system

    International Nuclear Information System (INIS)

    Pendergast, M.M.

    1980-05-01

    The Savannah River Laboratory's WIND minicomputer system allows quick and accurate assessment of an accidental release at the Savannah River Plant using data from eight meteorological towers. The accuracy of the assessment is largely determined by the accuracy of the meteorological data; therefore quality control is important in an emergency response system. Real-time quality control of this data will be added to the WIND system to automatically identify inaccurate data. Currently, the system averages the measurements from the towers to minimize the influence of inaccurate data being used in calculations. The computer code used in the real-time quality control has been previously used to identify inaccurate measurements from the archived tower data

  7. The meteorological monitoring audit, preventative maintenance and quality assurance programs at a former nuclear weapons facility

    International Nuclear Information System (INIS)

    Maxwell, D.R.

    1995-01-01

    The purposes of the meteorological monitoring audit, preventative maintenance, and quality assurance programs at the Rocky Flats Environmental Technology Site (Site), are to (1) support Emergency Preparedness (EP) programs at the Site in assessing the transport, dispersion, and deposition of effluents actually or potentially released into the atmosphere by Site operations; and (2) provide information for onsite and offsite projects concerned with the design of environmental monitoring networks for impact assessments, environmental surveillance activities, and remediation activities. The risk from the Site includes chemical and radioactive emissions historically related to nuclear weapons component production activities that are currently associated with storage of large quantities of radionuclides (plutonium) and radioactive waste forms. The meteorological monitoring program provides information for site-specific weather forecasting, which supports Site operations, employee safety, and Emergency Preparedness operations

  8. Review of uncertainty estimates associated with models for assessing the impact of breeder reactor radioactivity releases

    International Nuclear Information System (INIS)

    Miller, C.; Little, C.A.

    1982-08-01

    The purpose is to summarize estimates based on currently available data of the uncertainty associated with radiological assessment models. The models being examined herein are those recommended previously for use in breeder reactor assessments. Uncertainty estimates are presented for models of atmospheric and hydrologic transport, terrestrial and aquatic food-chain bioaccumulation, and internal and external dosimetry. Both long-term and short-term release conditions are discussed. The uncertainty estimates presented in this report indicate that, for many sites, generic models and representative parameter values may be used to calculate doses from annual average radionuclide releases when these calculated doses are on the order of one-tenth or less of a relevant dose limit. For short-term, accidental releases, especially those from breeder reactors located in sites dominated by complex terrain and/or coastal meteorology, the uncertainty in the dose calculations may be much larger than an order of magnitude. As a result, it may be necessary to incorporate site-specific information into the dose calculation under these circumstances to reduce this uncertainty. However, even using site-specific information, natural variability and the uncertainties in the dose conversion factor will likely result in an overall uncertainty of greater than an order of magnitude for predictions of dose or concentration in environmental media following shortterm releases

  9. Viking-1 meteorological measurements - First impressions

    Science.gov (United States)

    Hess, S. L.; Henry, R. M.; Leovy, C. B.; Tillman, J. E.; Ryan, J. A.

    1976-01-01

    A preliminary evaluation is given of in situ meteorological measurements made by Viking 1 on Mars. The data reported show that: (1) the atmosphere has approximate volume mixing ratios of 1.5% argon, 3% nitrogen, and 95% carbon dioxide; (2) the diurnal temperature range is large and regular, with a sunrise minimum of about 188 K and a midafternoon maximum near 244 K; (3) air and ground temperatures coincide quite closely during the night, but ground temperature exceeds air temperature near midday by as much as 25 C; (4) the winds exhibit a marked diurnal cycle; and (5) a large diurnal pressure variation with an afternoon minimum and an early-morning maximum parallels the wind pattern. The variations are explained in terms of familiar meteorological processes. It is suggested that latent heat is unlikely to play an important role on Mars because no evidence has been observed for traveling synoptic-scale disturbances such as those that occur in the terrestrial tropics.

  10. Meteorological effects on variation of airborne algae in Mexico

    Science.gov (United States)

    Rosas, Irma; Roy-Ocotla, Guadalupe; Mosiño, Pedro

    1989-09-01

    Sixteen species of algae were collected from 73.8 m3 of air. Eleven were obtained in Minatitlán and eleven in México City. The data show that similar diversity occurred between the two localities, in spite of the difference in altitude. This suggests that cosmopolitan airborne microorganisms might have been released from different sources. Three major algal divisions (Chlorophyta, Cyanophyta and Chrysophyta) formed the airborne algal group. Also, a large concentration of 2220 algae m-3 was found near sea-level, while lower amounts were recorded at the high altitude of México City. The genera Scenedesmus, Chlorella and Chlorococcum dominated. Striking relationships were noted between the concentration of airborne green and blue-green algae, and meteorological conditions such as rain, vapour pressure, temperature and winds for different altitudes. In Minatitlán a linear relationship was established between concentration of algae and both vapour pressure (mbar) and temperature (° C), while in México City the wind (m s-1) was associated with variations in the algal count.

  11. GPM GROUND VALIDATION METEOROLOGICAL TOWER ENVIRONMENT CANADA GCPEX V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The GPM Ground Validation Meteorological Tower Environment Canada GCPEx dataset provides temperature, relative humidity, 10 m winds, pressure and solar radiation...

  12. Monitoring Forsmark. Meteorological monitoring at Forsmark, January-December 2010

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Cari; Jones, Joergen (Swedish Meteorological and Hydrological Institute (SMHI), Norrkoeping (Sweden))

    2011-01-15

    In the Forsmark area, SKB's meteorological monitoring started in 2003 at the sites Storskaeret and Hoegmasten. However, since July 1, 2007 measurements are only performed at Hoegmasten. Measured and calculated parameters at Hoegmasten are precipitation and corrected precipitation, air temperature, barometric pressure, wind speed and direction, air humidity, global radiation and potential evapotranspiration. The Swedish Meteorological and Hydrological Institute, SMHI, has been responsible for planning and design, as well as for the operation of the stations used for meteorological monitoring. In general, the quality of the meteorological measurements during the period concerned, starting January 1, 2010, and ending December 31, 2010, has shown to be good

  13. Nowcasting Surface Meteorological Parameters Using Successive Correction Method

    National Research Council Canada - National Science Library

    Henmi, Teizi

    2002-01-01

    The successive correction method was examined and evaluated statistically as a nowcasting method for surface meteorological parameters including temperature, dew point temperature, and horizontal wind vector components...

  14. An intercomparison of several diagnostic meteorological processors used in mesoscale air quality modeling

    Energy Technology Data Exchange (ETDEWEB)

    Vimont, J.C. [National Park Service, Lakewood, CO (United States); Scire, J.S. [Sigma Research Corp., Concord, MA (United States)

    1994-12-31

    A major component, and area of uncertainty, in mesoscale air quality modeling, is the specification of the meteorological fields which affect the transport and dispersion of pollutants. Various options are available for estimating the wind and mixing depth fields over a mesoscale domain. Estimates of the wind field can be obtained from spatial and temporal interpolation of available observations or from diagnostic meteorological models, which estimate a meteorological field from available data and adjust those fields based on parameterizations of physical processes. A major weakness of these processors is their dependence on spatially and temporally sparse input data, particularly upper air data. These problems are exacerbated in regions of complex terrain and along the shorelines of large bodies of water. Similarly, the estimation of mixing depth is also reliant upon sparse observations and the parameterization of the convective and mechanical processes. The meteorological processors examined in this analysis were developed to drive different Lagrangian puff models. This paper describes the algorithms these processors use to estimate the wind fields and mixing depth fields.

  15. A real case simulation of the air-borne effluent dispersion on a typical summer day under CDA scenario for PFBR using an advanced meteorological and dispersion model

    International Nuclear Information System (INIS)

    Srinivas, C.V; Venkatesan, R.; Bagavath Singh, A.; Somayaji, K.M.

    2003-11-01

    Environmental concentrations and radioactive doses within and beyond the site boundary for the CDA situation of PFBR have been estimated using an Advanced Radiological Impact Prediction system for a real atmospheric situation on a typical summer day in the month of May 2003. The system consists of a meso-scale atmospheric prognostic model MM5 coupled with a random walk Lagrangian particle dispersion model FLEXPART for the simulation of transport, diffusion and deposition of radio nuclides. The details of the modeling system, its capabilities and various features are presented. The model has been validated for the simulated coastal atmospheric features of land-sea breeze, development of TIBL etc., with site and regional meteorological observations from IMD. Analysis of the dose distribution in a situation that corresponds to the atmospheric conditions on the chosen day shows that the doses for CDA through different pathways are 8 times less than the earlier estimations made according to regulatory requirements using the Gaussian Plume Model (GPM) approach. However for stack releases a higher dose than was reported earlier occurred beyond the site boundary at 2-4 km range under stable and fumigation conditions. The doses due to stack releases under these conditions maintained almost the same value in 3 to 10 km range and decreased there after. Deposition velocities computed from radionuclide species, wind speed, surface properties were 2 orders lower than the values used earlier and hence gave more realistic estimates of ground deposited activity. The study has enabled to simulate the more complex meteorological situation that actually is present at the site of interest and the associated spatial distribution of radiological impact around Kalpakkam. In order to draw meaningful conclusion that can be compared with regulatory estimates future study would be undertaken to simulate the dispersion under extreme meteorological situations which could possibly be worse than

  16. METEOROLOGICAL INFLUENCES ON VAPOR INCIDENTS IN THE 200 EAST and 200 WEST TANK FARMS FROM CY1995 TO CY2004

    International Nuclear Information System (INIS)

    HOCKING, M.J.

    2005-01-01

    Revised for a more comprehensive overview of vapor incidents reported at the Hanford Tank Farms. Investigation into the meteorological influences on vapor incidents in the tank farm to determine what, if any, meteorological influences contribute to the reporting of odors, smells, vapors, and other gases. Weather phenomena, specifically barometric pressure, and wind velocity and direction can potentially cause or exacerbate a vapor release within the farm systems. The purpose of this document is to gather and evaluate the meteorological and weather information for the Tank Farms Shift Log Vapor Incident entries and determine what, if any, meteorological influences contribute to the reporting of odors, smells, vapors, and other gases such as propane. A part of the evaluation will be determining which of the incidents are related to actual ''intrusive'' work, and which are ''transient.'' Transient vapor incidents are herein defined as those vapors encountered during walkdowns, surveys, or other activities that did not require working directly with the tanks, pits, transfer lines, etc. Another part of the investigation will involve determining if there are barometric pressures or other weather related phenomena that might cause or contribute vapors being released when there are no ''intrusive'' activities. A final purpose is to evaluate whether there is any correlation between the 242-A Evaporator operations and Vapor Incidents entered on the Shift Log

  17. METEOROLOGICAL INFLUENCES ON VAPOR INCIDENTS IN THE 200 EAST & 200 WEST TANK FARMS FROM CY1995 TO CY2004

    Energy Technology Data Exchange (ETDEWEB)

    HOCKING, M.J.

    2005-01-31

    Revised for a more comprehensive overview of vapor incidents reported at the Hanford Tank Farms. Investigation into the meteorological influences on vapor incidents in the tank farm to determine what, if any, meteorological influences contribute to the reporting of odors, smells, vapors, and other gases. Weather phenomena, specifically barometric pressure, and wind velocity and direction can potentially cause or exacerbate a vapor release within the farm systems. The purpose of this document is to gather and evaluate the meteorological and weather information for the Tank Farms Shift Log Vapor Incident entries and determine what, if any, meteorological influences contribute to the reporting of odors, smells, vapors, and other gases such as propane. A part of the evaluation will be determining which of the incidents are related to actual ''intrusive'' work, and which are ''transient.'' Transient vapor incidents are herein defined as those vapors encountered during walkdowns, surveys, or other activities that did not require working directly with the tanks, pits, transfer lines, etc. Another part of the investigation will involve determining if there are barometric pressures or other weather related phenomena that might cause or contribute vapors being released when there are no ''intrusive'' activities. A final purpose is to evaluate whether there is any correlation between the 242-A Evaporator operations and Vapor Incidents entered on the Shift Log.

  18. Meteorological research studies at Jervis Bay, Australia

    International Nuclear Information System (INIS)

    Clark, G.H.; Bendun, E.O.K.

    1974-07-01

    A climatological study of the winds and temperature from the Jervis Bay region which commenced in October 1970 has shown the presence of a coastal sea breeze and secondary bay breeze circulation system. In an attempt to define the influence of the Murray's Beach site on the local atmospheric dispersion, special smoke plume photography studies were conducted in the lower atmosphere. In June 1972 a meteorological acoustic sounding research programme was initiated at the Jervis Bay settlement. The aims of the research are to calibrate the sounder in terms of surface wind, turbulence and temperature measurements pertinent to a description of the lower atmospheric dispersion potential. Preliminary results on six months' data have shown encouraging correlations between the acoustic sounder patterns and particularly the wind direction turbulence traces. (author)

  19. Meteorología y clima

    OpenAIRE

    Alarcón Jordán, Marta; Casas Castillo, M. del Carmen

    1999-01-01

    Este libro constituye una introducción al estudio de la atmósfera en los campos de la meteorología y la climatología. Se ha concebido especialmente como herramienta de apoyo para los estudiantes de ciencias y tecnología que inician los estudios de estos temas. El libro incorpora un programa informático de simulación del cambio climático. En él se exponen las características generales de la atmósfera, su estructura física y la composición química y también se hace una introducción al proble...

  20. Multifractal Conceptualisation of Hydro-Meteorological Extremes

    Science.gov (United States)

    Tchiguirinskaia, I.; Schertzer, D.; Lovejoy, S.

    2009-04-01

    Hydrology and more generally sciences involved in water resources management, technological or operational developments face a fundamental difficulty: the extreme variability of hydro-meteorological fields. It clearly appears today that this variability is a function of the observation scale and yield hydro-meteorological hazards. Throughout the world, the development of multifractal theory offers new techniques for handling such non-classical variability over wide ranges of time and space scales. The resulting stochastic simulations with a very limited number of parameters well reproduce the long range dependencies and the clustering of rainfall extremes often yielding fat tailed (i.e., an algebraic type) probability distributions. The goal of this work was to investigate the ability of using very short or incomplete data records for reliable statistical predictions of the extremes. In particular we discuss how to evaluate the uncertainty in the empirical or semi-analytical multifractal outcomes. We consider three main aspects of the evaluation, such as the scaling adequacy, the multifractal parameter estimation error and the quantile estimation error. We first use the multiplicative cascade model to generate long series of multifractal data. The simulated samples had to cover the range of the universal multifractal parameters widely available in the scientific literature for the rainfall and river discharges. Using these long multifractal series and their sub-samples, we defined a metric for parameter estimation error. Then using the sets of estimated parameters, we obtained the quantile values for a range of excedance probabilities from 5% to 0.01%. Plotting the error bars on a quantile plot enable an approximation of confidence intervals that would be particularly important for the predictions of multifractal extremes. We finally illustrate the efficiency of such concept on its application to a large database (more than 16000 selected stations over USA and

  1. GEMPAK 5.1 - A GENERAL METEOROLOGICAL PACKAGE (UNIX VERSION)

    Science.gov (United States)

    Desjardins, M. L.

    1994-01-01

    GEMPAK is a general meteorological software package developed at NASA/Goddard Space Flight Center. It includes programs to analyze and display surface, upper-air, and gridded data, including model output. There are very general programs to list, edit, and plot data on maps, to display profiles and time series, to draw and fill contours, to draw streamlines, to plot symbols for clouds, sky cover, and pressure tendency, and draw cross sections in the case of gridded data and sounding data. In addition, there are Barnes objective analysis programs to grid surface and upper-air data. The programs include the capabilities to derive meteorological parameters from those found in the dataset, to perform vertical interpolations of sounding data to different coordinate systems, and to compute an extensive set of gridded diagnostic quantities by specifying various nested combinations of scalars and vector arithmetic, algebraic, and differential operators. The GEMPAK 5.1 graphics/transformation subsystem, GEMPLT, provides device-independent graphics. GEMPLT also has the capability to display output in a variety of map projections or overlaid on satellite imagery. GEMPAK 5.1 is written in FORTRAN 77 and C-language and has been implemented on VAX computers under VMS and on computers running the UNIX operating system. During installation and normal use, this package occupies approximately 100Mb of hard disk space. The UNIX version of GEMPAK includes drivers for several graphic output systems including MIT's X Window System (X11,R4), Sun GKS, PostScript (color and monochrome), Silicon Graphics, and others. The VMS version of GEMPAK also includes drivers for several graphic output systems including PostScript (color and monochrome). The VMS version is delivered with the object code for the Transportable Applications Environment (TAE) program, version 4.1 which serves as a user interface. A color monitor is recommended for displaying maps on video display devices. Data for rendering

  2. Medical Meteorology: the Relationship between Meteorological Parameters (Humidity, Rainfall, Wind, and Temperature and Brucellosis in Zanjan Province

    Directory of Open Access Journals (Sweden)

    Yousefali Abedini

    2016-06-01

    Full Text Available Background: Brucellosis (Malta fever is a major contagious zoonotic disease, with economic and public health importance. Methods To assess the effect of meteorological (temperature, rainfall, humidity, and wind and climate parameters on incidence of brucellosis, brucellosis distribution and meteorological zoning maps of Zanjan Province were prepared using Inverse Distance Weighting (IDW and Kriging technique in Arc GIS medium. Zoning maps of mean temperature, rainfall, humidity, and wind were compared to brucellosis distribution maps. Results: Correlation test showed no relationship between the mean number of patients with brucellosis and any of the four meteorological parameters. Conclusion: It seems that in Zanjan province there is no correlation between brucellosis and meteorological parameters.

  3. A portable meteorological station plus nuclear radiation monitoring system using a basic-8052 micro-controller

    International Nuclear Information System (INIS)

    Al-Mohamad, A.; Aghabi, S.; Weiss, C.

    2002-01-01

    a portable meteorology station capable of measuring various atmospheric parameters (mainly ambient temperature, relative humidity, atmospheric pressure, wind speed and direction) was designed and built. The physical quantities were converted to electrical signals using suitable sensors. These signals were then processed and transferred to digital values to be stored in suitable memories. A nuclear radiation alarm system was also built, on the main board, to monitor the nuclear radiation releases levels. The system consists of three main parts: control board, data acquisition board and signals conditioning board. the overall system is controlled by a BASIC-8052 micro-controller. (authors)

  4. Variations in environmental tritium doses due to meteorological data averaging and uncertainties in pathway model parameters

    Energy Technology Data Exchange (ETDEWEB)

    Kock, A.

    1996-05-01

    The objectives of this research are: (1) to calculate and compare off site doses from atmospheric tritium releases at the Savannah River Site using monthly versus 5 year meteorological data and annual source terms, including additional seasonal and site specific parameters not included in present annual assessments; and (2) to calculate the range of the above dose estimates based on distributions in model parameters given by uncertainty estimates found in the literature. Consideration will be given to the sensitivity of parameters given in former studies.

  5. Variations in environmental tritium doses due to meteorological data averaging and uncertainties in pathway model parameters

    International Nuclear Information System (INIS)

    Kock, A.

    1996-05-01

    The objectives of this research are: (1) to calculate and compare off site doses from atmospheric tritium releases at the Savannah River Site using monthly versus 5 year meteorological data and annual source terms, including additional seasonal and site specific parameters not included in present annual assessments; and (2) to calculate the range of the above dose estimates based on distributions in model parameters given by uncertainty estimates found in the literature. Consideration will be given to the sensitivity of parameters given in former studies

  6. Comparison of methods for generating typical meteorological year using meteorological data from a tropical environment

    Energy Technology Data Exchange (ETDEWEB)

    Janjai, S.; Deeyai, P. [Laboratory of Tropical Atmospheric Physics, Department of Physics, Faculty of Science, Silpakorn University, Nakhon Pathom 73000 (Thailand)

    2009-04-15

    This paper presents the comparison of methods for generating typical meteorological year (TMY) data set using a 10-year period of meteorological data from four stations in a tropical environment of Thailand. These methods are the Sadia National Laboratory method, the Danish method and the Festa and Ratto method. In investigating their performance, these methods were employed to generate TMYs for each station. For all parameters of the TMYs and the stations, statistical test indicates that there is no significant difference between the 10-year average values of these parameters and the corresponding average values from TMY generated from each method. The TMY obtained from each method was also used as input data to simulate two solar water heating systems and two photovoltaic systems with different sizes at the four stations by using the TRNSYS simulation program. Solar fractions and electrical output calculated using TMYs are in good agreement with those computed employing the 10-year period hourly meteorological data. It is concluded that the performance of the three methods has no significant difference for all stations under this investigation. Due to its simplicity, the method of Sandia National Laboratories is recommended for the generation of TMY for this tropical environment. The TMYs developed in this work can be used for solar energy and energy conservation applications at the four locations in Thailand. (author)

  7. Sensitivity and uncertainty studies of the CRAC2 code for selected meteorological models and parameters

    International Nuclear Information System (INIS)

    Ward, R.C.; Kocher, D.C.; Hicks, B.B.; Hosker, R.P. Jr.; Ku, J.Y.; Rao, K.S.

    1985-01-01

    We have studied the sensitivity of results from the CRAC2 computer code, which predicts health impacts from a reactor-accident scenario, to uncertainties in selected meteorological models and parameters. The sources of uncertainty examined include the models for plume rise and wet deposition and the meteorological bin-sampling procedure. An alternative plume-rise model usually had little effect on predicted health impacts. In an alternative wet-deposition model, the scavenging rate depends only on storm type, rather than on rainfall rate and atmospheric stability class as in the CRAC2 model. Use of the alternative wet-deposition model in meteorological bin-sampling runs decreased predicted mean early injuries by as much as a factor of 2-3 and, for large release heights and sensible heat rates, decreased mean early fatalities by nearly an order of magnitude. The bin-sampling procedure in CRAC2 was expanded by dividing each rain bin into four bins that depend on rainfall rate. Use of the modified bin structure in conjunction with the CRAC2 wet-deposition model changed all predicted health impacts by less than a factor of 2. 9 references

  8. Weather scenarios for dose calculations with incomplete meteorological data. V.IV

    International Nuclear Information System (INIS)

    Alp, E.; Lam, L.H.; Moran, M.D.

    1985-09-01

    This report documents a study to substantiate or modify the weather scenarios proposed by the Atomic Energy Control Board Staff Position Paper on meteorological acceptance criteria for estimating the potential radiological consequences of postulated accidents (AECB, 1982) for short-, prolonged-, and long-term releases from ground level and elevated sources. The study examined available meteorological data in Canada to determine whether the AECB-proposed scenarios are sufficiently general that they are appropriate and conservative for any potential nuclear power plant in Canada, but also realistic, i.e., not so conservative that the results of dose calculations using these scenarios would be wholly unrepresentative leading to incorrect design decisions. Three different sets of scenarios were derived using three site-specific data sets from weather stations that are representative of existing nuclear power plants in Canada. When compared, the scenarios for the three sites are not significantly different from each other, especially in terms of trends, considering that they have been based on data from widely differing meteorological regions in Canada. Conservative envelopes of the scenarios for the three sites were taken to give the recommended general weather scenario set. The recommended set was then compared with the AECB proposed scenarios. The recommended scenarios are, in general, conservative

  9. Weather scenarios for dose calculations with incomplete meteorological data. V.I.(rev.1)

    International Nuclear Information System (INIS)

    Alp, E.; Lam, L.H.; Moran, M.D.

    1985-09-01

    This report documents a study to substantiate or modify the weather scenarios proposed by the Atomic Energy Control Board Staff Position Paper on meteorological acceptance criteria for estimating the potential radiological consequences of postulated accidents (AECB, 1982) for short-, prolonged-, and long-term releases from ground level and elevated sources. The study examined available meteorological data in Canada to determine whether the AECB-proposed scenarios are sufficiently general that they are appropriate and conservative for any potential nuclear power plant in Canada, but also realistic, i.e., not so conservative that the results of dose calculations using these scenarios would be wholly unrepresentative leading to incorrect design decisions. Three different sets of scenarios were derived using three site-specific data sets from weather stations that are representative of existing nuclear power plants in Canada. When compared, the scenarios for the three sites are not significantly different from each other, especially in terms of trends, considering that they have been based on data from widely differing meteorological regions in Canada. Conservative envelopes of the scenarios for the three sites were taken to give the recommended general weather scenario set. The recommended set was then compared with the AECB proposed scenarios. The recommended scenarios are, in general, conservative

  10. Annual report of the Dynamic Meteorology Laboratory, 1986

    International Nuclear Information System (INIS)

    1987-01-01

    Research on climate simulation; data assimilation and forecasting; nonlinear dynamics and atmospheric turbulence; wave dynamics in the middle atmosphere; African and tropical meteorology and climatology; spectroscopy and modeling of atmospheric radiation; satellite meteorology and climatology; and active lidar remote sensing is presented [fr

  11. Brookhaven National Laboratory meteorological services instrument calibration plan and procedures

    Energy Technology Data Exchange (ETDEWEB)

    Heiser, John [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2013-02-16

    This document describes the Meteorological Services (Met Services) Calibration and Maintenance Schedule and Procedures, The purpose is to establish the frequency and mechanism for the calibration and maintenance of the network of meteorological instrumentation operated by Met Services. The goal is to maintain the network in a manner that will result in accurate, precise and reliable readings from the instrumentation.

  12. Climatic condition of Calabar as typified by some meteorological ...

    African Journals Online (AJOL)

    This study aims at analysing some meteorological data collected by the meteorological department of the Margaret Ekpo International Airport, Calabar between 1985 and 2003. The main objectives were to provide average figures and curves of Calabar climate, and to identify possible trends since 1985. Results show that ...

  13. Meteorological aspects of site selection for nuclear power plants

    International Nuclear Information System (INIS)

    Artemova, N.E.

    1983-01-01

    Factors are considered that characterize the NPP safe layout in a specified region and the physicogeographical conditions determining the meteorological dilution coefficient of NPP radioactive wastes in the atmosphere. A three-point scale system is proposed for estimating physicogeographical factors in three ''fitness'' classes. The data required for calculating meteorological dilution coefficient are given

  14. 10 CFR 960.5-2-3 - Meteorology.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Meteorology. 960.5-2-3 Section 960.5-2-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Preclosure Guidelines Preclosure Radiological Safety § 960.5-2-3 Meteorology. (a) Qualifying...

  15. Meteorological Observations Available for the State of Utah

    Energy Technology Data Exchange (ETDEWEB)

    Wharton, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-09-12

    The National Weather Service’s Meteorological Assimilation Data Ingest System (MADIS) contains a large number of station networks of surface and upper air meteorological observations for the state of Utah. In addition to MADIS, observations from individual station networks may also be available. It has been confirmed that LLNL has access to the data sources listed below.

  16. Propagation of hydro-meteorological uncertainty in a model cascade framework to inundation prediction

    Science.gov (United States)

    Rodríguez-Rincón, J. P.; Pedrozo-Acuña, A.; Breña-Naranjo, J. A.

    2015-07-01

    This investigation aims to study the propagation of meteorological uncertainty within a cascade modelling approach to flood prediction. The methodology was comprised of a numerical weather prediction (NWP) model, a distributed rainfall-runoff model and a 2-D hydrodynamic model. The uncertainty evaluation was carried out at the meteorological and hydrological levels of the model chain, which enabled the investigation of how errors that originated in the rainfall prediction interact at a catchment level and propagate to an estimated inundation area and depth. For this, a hindcast scenario is utilised removing non-behavioural ensemble members at each stage, based on the fit with observed data. At the hydrodynamic level, an uncertainty assessment was not incorporated; instead, the model was setup following guidelines for the best possible representation of the case study. The selected extreme event corresponds to a flood that took place in the southeast of Mexico during November 2009, for which field data (e.g. rain gauges; discharge) and satellite imagery were available. Uncertainty in the meteorological model was estimated by means of a multi-physics ensemble technique, which is designed to represent errors from our limited knowledge of the processes generating precipitation. In the hydrological model, a multi-response validation was implemented through the definition of six sets of plausible parameters from past flood events. Precipitation fields from the meteorological model were employed as input in a distributed hydrological model, and resulting flood hydrographs were used as forcing conditions in the 2-D hydrodynamic model. The evolution of skill within the model cascade shows a complex aggregation of errors between models, suggesting that in valley-filling events hydro-meteorological uncertainty has a larger effect on inundation depths than that observed in estimated flood inundation extents.

  17. PROMET - The Journal of Meteorological Education issued by DWD

    Science.gov (United States)

    Rapp, J.

    2009-09-01

    Promet is published by the German Meteorological Service (DWD) since 1971 to improve meteorologists and weather forecasters skills. The journal comprises mainly contributions to topics like biometeorology, the NAO, or meteorology and insurance business. The science-based articles should illustrate the special issue in an understandable and transparent way. In addition, the journal contains portraits of other national meteorological services and university departments, book reviews, list of university degrees, and other individual papers. Promet is published only in German language, but included English titles and abstracts. The journal is peer-reviewed by renowned external scientists. It is distributed free of charge by DWD to the own meteorological staff. On the other hand, DMG (the German Meteorological Society) hand it out to all members of the society. The current issues deal with "Modern procedures of weather forecasting in DWD” and "E-Learning in Meteorology”.

  18. The data collection component of the Hanford Meteorology Monitoring Program

    Energy Technology Data Exchange (ETDEWEB)

    Glantz, C.S.; Islam, M.M.

    1988-09-01

    An intensive program of meteorological monitoring is in place at the US Department of Energy's Hanford Site. The Hanford Meteorology Monitoring Program involves the measurement, observation, and storage of various meteorological data; continuous monitoring of regional weather conditions by a staff of professional meteorologists; and around-the-clock forecasting of weather conditions for the Hanford Site. The objective of this report is to document the data collection component of the program. In this report, each meteorological monitoring site is discussed in detail. Each site's location and instrumentation are described and photographs are presented. The methods for processing and communicating data to the Hanford Meteorology Station are also discussed. Finally, the procedures followed to maintain and calibrate these instruments are presented. 2 refs., 83 figs., 15 tabs.

  19. BUBBLE - an urban boundary layer meteorology project

    DEFF Research Database (Denmark)

    Rotach, M.W.; Vogt, R.; Bernhofer, C.

    2005-01-01

    ground truth, as well as on urban turbulence and profiling (sodar, RASS, tethered balloon) were performed. Also tracer experiments with near-roof-level release and sampling were performed. In parallel to the experimental activities within BUBBLE, a meso-scale numerical atmospheric model, which contains...

  20. Mathematical models for atmospheric pollutants. Appendix A. Elements of meteorology. Final report

    International Nuclear Information System (INIS)

    Drake, R.L.; Laulainen, N.S.

    1979-08-01

    The meteorological elements that are important in the transport and fate of airborne pollutants are summarized. The summary consists of descriptions of the thermal, water, kinematic and dynamic structures of the atmosphere, the time and space scale classifications of atmospheric motions, and modifications of pollutant plumes as they pass over nonhomogeneous surface conditions and complex terrain. The discussions consider the atmospheric thermal layers and their stability, formation of clouds and the production of rain and snow, the movement of air masses and weather fronts, the horizontal winds in the planetary boundary layer, and wind profiles over transition zones and complex terrain

  1. Synopsis of TC4 Missions and Meteorology

    Science.gov (United States)

    Starr, D.; Pfister, L.; Selkirk, H.; Nguyen, L.

    2007-12-01

    The TC4 (Tropical Composition, Clouds and Climate Coupling) Experiment conducted 26 aircraft sorties on 13 flight days from July 17 to August 8, 2007 (23 days). Quality science observations were also obtained during the transit flights to/from from San Jose, Costa Rica, where the mission was based. On 9 days, coordinated aircraft missions were flown with the NASA ER-2 and DC-8, and with the NASA WB-57 on 3 occasions (and transit flights). The ER-2 served as an A-Train simulator (MODIS, CloudSat, CALIPSO, AIRS/TES, partial AMSR-E) while the WB-57 provided in-situ measurements of upper tropospheric cloud particles, aerosols and trace gases. The DC-8 provided both in-situ and remote sensing measurements, where the latter were focused on Aura validation, and also including a down-looking scanning precipitation radar (TRMM PR simulator). This paper will provide a synopsis of the science observations that were obtained, as regards the clouds and cloud systems sampled, from a meteorological perspective. A diversity of clouds were sampled and the meteorology proved more interesting than expected, at least to this author. Upper tropospheric cirrus outflows were sampled from a number of convective cloud systems including ITCZ-type systems as well as systems close to and affected by land. The low level inflows to these systems were also sampled in some cases (DC-8) and missions were flown to sample stratocumulus clouds over the Pacific Ocean exploiting the unique instrumentation on the DC-8 to add to the knowledge of these clouds which are so important to the Earth radiation budget. Measurements were made in the tropical Tropopause Transition Layer (TTL) by the WB-57. Upper tropospheric clouds and TTL properties and processes were central TC4 objectives. Excellent data were also obtained on the fate of the Saharan Air Layer and its aerosols over the Caribbean and Central America, as well as samples of plumes from volcanoes in Ecuador and Columbia and biogenic emissions over

  2. Providing Meteorological Information for Controlled Burns at the Savannah River Site

    International Nuclear Information System (INIS)

    Buckley, R.

    1999-01-01

    Regional and local weather information are important for a variety of applications at the Savannah River Site (SRS), a Department of Energy (DOE) facility covering approximately 800 square kilometers of southwest South Carolina east of the Savannah River. For example, meteorological observations and forecasts are used to assess the consequences of an accidental radiological or chemical release. Traditionally, hazards posed by SRS operations have been associated with nuclear reactors, chemical reprocessing plants, fuel fabrication, or waste-vitrification facilities. However, recent events have shown site-specific meteorology to be a valuable tool to the United States Forest Service (USFS) in mitigating potential hazards from controlled burns that are conducted at the SRS. Prescribed burns at the SRS are important for a variety of reasons. The removal of thick undergrowth allows wildlife to more easily feed and migrate, accelerates the growth of young pine stands, and controls certain diseases that affect local pine forests (e.g. Adams et al. 1973). In addition, the removal of twigs, pine needles, or leaves (a fuel source) reduces the chance of serious wildfire damage. However, the threat of smoke inhalation and reduced visibility requires careful planning on the part of the fire professionals. At the SRS, approximately 100 square kilometers of land per year are burned in a controlled manner, mainly in the spring.To reduce the potentially harmful effects to any onsite activity, it is important that USFS personnel understand current and predicted weather patterns within the area. This paper discusses two sources of meteorological information that are provided to SRS-USFS personnel for use in planning forest burns: (1) a meteorological tower system which provides current data from a series of onsite locations, and (2) an operational prognostic mesoscale model used to generate forecast information. The forecast data supplements the basic National Weather Service (NWS

  3. Sea-air boundary meteorological sensor

    Science.gov (United States)

    Barbosa, Jose G.

    2015-05-01

    The atmospheric environment can significantly affect radio frequency and optical propagation. In the RF spectrum refraction and ducting can degrade or enhance communications and radar coverage. Platforms in or beneath refractive boundaries can exploit the benefits or suffer the effects of the atmospheric boundary layers. Evaporative ducts and surface-base ducts are of most concern for ocean surface platforms and evaporative ducts are almost always present along the sea-air interface. The atmospheric environment also degrades electro-optical systems resolution and visibility. The atmospheric environment has been proven not to be uniform and under heterogeneous conditions substantial propagation errors may be present for large distances from homogeneous models. An accurate and portable atmospheric sensor to profile the vertical index of refraction is needed for mission planning, post analysis, and in-situ performance assessment. The meteorological instrument used in conjunction with a radio frequency and electro-optical propagation prediction tactical decision aid tool would give military platforms, in real time, the ability to make assessments on communication systems propagation ranges, radar detection and vulnerability ranges, satellite communications vulnerability, laser range finder performance, and imaging system performance predictions. Raman lidar has been shown to be capable of measuring the required atmospheric parameters needed to profile the atmospheric environment. The atmospheric profile could then be used as input to a tactical decision aid tool to make propagation predictions.

  4. Influence of seasonal and meteorological factors on nuclear emergency planning. Report by a group of consultants

    International Nuclear Information System (INIS)

    1991-01-01

    The extent of the consequences of an accidental release of radioactivity is strongly dependent upon a wide number of parameters. In particular, the characteristics of the source term, and seasonal, climatic and meteorological conditions have a substantial influence on the physical factors involved in transport and deposition of airborne contaminants, and on the transfer and accumulation of radionuclides in terrestrial and aquatic ecosystems. These environmental conditions also have a significant influence on living habits and practices, and thus on potential radiological and economic impacts. Moreover, these conditions may affect the features and the impact of countermeasures which are adopted for the protection of the public in the event of an accidental release. The NEA organized a workshop to discuss such matters. The workshop provided a review of the influence of such environmental conditions as season, climate and weather on the radiological consequences of an accident, and on the implication of these conditions for the implementation of mitigative measures

  5. Meteorological effects of thermal energy releases (METER) program. Progress report, October 1980-September 1982

    International Nuclear Information System (INIS)

    Patrinos, A.A.N.; Hoffman, H.W.

    1983-03-01

    This report examines the inadvertent weather modification effects of large cooling towers and cooling ponds. Emphasis was placed on field studies, and the focus of the program was on a precipitation modification study around the Bowen Electric Generating Plant in northwestern Georgia. The field effort includes the study of wetfall chemistry in the plant's vicinity. The analysis of three years of precipitation data have failed to show a significant effect of the plant on rainfall volume; the investigation of rainfall pattern variability has been inconclusive. The studies of wetfall chemistry have provided valuable information on the mechanisms of plume washout from large point sources and on the general characteristics of precipitation chemistry in the southeastern US

  6. Meteorological effects of heat and moisture releases from large power stations (precipitation modification)

    International Nuclear Information System (INIS)

    Patrinos, A.A.N.; Eissenberg, D.M.

    1978-01-01

    The Bowen Electric Generating Plant (Plant Bowen) in Northwest Georgia has been chosen as a test site to investigate the atmospheric effects of cooling towers. This 3,200-MWe coal-fired power plant uses four natural-draft cooling towers and is the largest of U.S. power plants having cooling towers as the sole cooling method. Results are reported from both climatological and field studies. Extensive use has been made of the U.S. National Weather Service (NWS) data accumulated over several decades in Northwest Georgia. Apart from providing preliminary indications of precipitation modification effects, these data have aided in the general understanding of the climatology in the vicinity of Plant Bowen and have paved the way for the field studies currently underway. These field studies, employing a dense network of rain gauges and windsets, are expected to provide the statistical data base necessary to estimate the plant's effect (if any) on precipitation

  7. Green River air quality model development: meteorological and tracer data, July/August 1982 field study in Brush Valley, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    Whiteman, C.D.; Lee, R.N.; Orgill, M.M.; Zak, B.D.

    1984-06-01

    Meteorological and atmospheric tracer studies were conducted during a 3-week period in July and August of 1982 in the Brush Creek Valley of northwestern Colorado. The objective of the field experiments was to obtain data to evaluate a model, called VALMET, developed at PNL to predict dispersion of air pollutants released from an elevated stack located within a deep mountain valley in the post-sunrise temperature inversion breakup period. Three tracer experiments were conducted in the valley during the 2-week period. In these experiments, sulfur hexafluoride (SF/sub 6/) was released from a height of approximately 100 m, beginning before sunrise and continuing until the nocturnal down-valley winds reversed several hours after sunrise. Dispersion of the sulfur hexafluoride after release was evaluated by measuring SF/sub 6/ concentrations in ambient air samples taken from sampling devices operated within the valley up to about 8 km down valley from the source. An instrumented research aircraft was also used to measure concentrations in and above the valley. Tracer samples were collected using a network of radio-controlled bag sampling stations, two manually operated gas chromatographs, a continuous SF/sub 6/ monitor, and a vertical SF/sub 6/ profiler. In addition, basic meteorological data were collected during the tracer experiments. Frequent profiles of vertical wind and temperature structure were obtained with tethered balloons operated at the release site and at a site 7.7 km down the valley from the release site. 10 references, 63 figures, 50 tables.

  8. Application of WRF/Chem-MADRID and WRF/Polyphemus in Europe - Part 1: Model description, evaluation of meteorological predictions, and aerosol-meteorology interactions

    Science.gov (United States)

    Zhang, Y.; Sartelet, K.; Wu, S.-Y.; Seigneur, C.

    2013-07-01

    Comprehensive model evaluation and comparison of two 3-D air quality modeling systems (i.e., the Weather Research and Forecast model (WRF)/Polyphemus and WRF with chemistry and the Model of Aerosol Dynamics, Reaction, Ionization, and Dissolution (MADRID) (WRF/Chem-MADRID)) are conducted over Western Europe. Part 1 describes the background information for the model comparison and simulation design, the application of WRF for January and July 2001 over triple-nested domains in Western Europe at three horizontal grid resolutions: 0.5°, 0.125°, and 0.025°, and the effect of aerosol/meteorology interactions on meteorological predictions. Nine simulated meteorological variables (i.e., downward shortwave and longwave radiation fluxes (SWDOWN and LWDOWN), outgoing longwave radiation flux (OLR), temperature at 2 m (T2), specific humidity at 2 m (Q2), relative humidity at 2 m (RH2), wind speed at 10 m (WS10), wind direction at 10 m (WD10), and precipitation (Precip)) are evaluated using available observations in terms of spatial distribution, domainwide daily and site-specific hourly variations, and domainwide performance statistics. The vertical profiles of temperature, dew points, and wind speed/direction are also evaluated using sounding data. WRF demonstrates its capability in capturing diurnal/seasonal variations and spatial gradients and vertical profiles of major meteorological variables. While the domainwide performance of LWDOWN, OLR, T2, Q2, and RH2 at all three grid resolutions is satisfactory overall, large positive or negative biases occur in SWDOWN, WS10, and Precip even at 0.125° or 0.025° in both months and in WD10 in January. In addition, discrepancies between simulations and observations exist in T2, Q2, WS10, and Precip at mountain/high altitude sites and large urban center sites in both months, in particular, during snow events or thunderstorms. These results indicate the model's difficulty in capturing meteorological variables in complex terrain and

  9. Application of WRF/Chem-MADRID and WRF/Polyphemus in Europe – Part 1: Model description, evaluation of meteorological predictions, and aerosol–meteorology interactions

    Directory of Open Access Journals (Sweden)

    Y. Zhang

    2013-07-01

    Full Text Available Comprehensive model evaluation and comparison of two 3-D air quality modeling systems (i.e., the Weather Research and Forecast model (WRF/Polyphemus and WRF with chemistry and the Model of Aerosol Dynamics, Reaction, Ionization, and Dissolution (MADRID (WRF/Chem-MADRID are conducted over Western Europe. Part 1 describes the background information for the model comparison and simulation design, the application of WRF for January and July 2001 over triple-nested domains in Western Europe at three horizontal grid resolutions: 0.5°, 0.125°, and 0.025°, and the effect of aerosol/meteorology interactions on meteorological predictions. Nine simulated meteorological variables (i.e., downward shortwave and longwave radiation fluxes (SWDOWN and LWDOWN, outgoing longwave radiation flux (OLR, temperature at 2 m (T2, specific humidity at 2 m (Q2, relative humidity at 2 m (RH2, wind speed at 10 m (WS10, wind direction at 10 m (WD10, and precipitation (Precip are evaluated using available observations in terms of spatial distribution, domainwide daily and site-specific hourly variations, and domainwide performance statistics. The vertical profiles of temperature, dew points, and wind speed/direction are also evaluated using sounding data. WRF demonstrates its capability in capturing diurnal/seasonal variations and spatial gradients and vertical profiles of major meteorological variables. While the domainwide performance of LWDOWN, OLR, T2, Q2, and RH2 at all three grid resolutions is satisfactory overall, large positive or negative biases occur in SWDOWN, WS10, and Precip even at 0.125° or 0.025° in both months and in WD10 in January. In addition, discrepancies between simulations and observations exist in T2, Q2, WS10, and Precip at mountain/high altitude sites and large urban center sites in both months, in particular, during snow events or thunderstorms. These results indicate the model's difficulty in capturing meteorological variables in complex

  10. Meteorological characteristics of nuclear installations sites

    International Nuclear Information System (INIS)

    Doumenc, A.

    1988-01-01

    The atmosphere is the most propitious medium to a rapid transport and diffusion of a pollutant. So, it is important to know its local characteristics which is decisive for every evaluation of radioactive release consequences using transfer models. It is also the siege of intense sudden hazardous phenomena, as tornados and typhoons, that should be taken into account in the installation conception. 1 tab., 6 refs. (F.M.)

  11. Configuring the HYSPLIT Model for National Weather Service Forecast Office and Spaceflight Meteorology Group Applications

    Science.gov (United States)

    Dreher, Joseph; Blottman, Peter F.; Sharp, David W.; Hoeth, Brian; Van Speybroeck, Kurt

    2009-01-01

    The National Weather Service Forecast Office in Melbourne, FL (NWS MLB) is responsible for providing meteorological support to state and county emergency management agencies across East Central Florida in the event of incidents involving the significant release of harmful chemicals, radiation, and smoke from fires and/or toxic plumes into the atmosphere. NWS MLB uses the National Oceanic and Atmospheric Administration Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model to provide trajectory, concentration, and deposition guidance during such events. Accurate and timely guidance is critical for decision makers charged with protecting the health and well-being of populations at risk. Information that can describe the geographic extent of areas possibly affected by a hazardous release, as well as to indicate locations of primary concern, offer better opportunity for prompt and decisive action. In addition, forecasters at the NWS Spaceflight Meteorology Group (SMG) have expressed interest in using the HYSPLIT model to assist with Weather Flight Rules during Space Shuttle landing operations. In particular, SMG would provide low and mid-level HYSPLIT trajectory forecasts for cumulus clouds associated with smoke plumes, and high-level trajectory forecasts for thunderstorm anvils. Another potential benefit for both NWS MLB and SMG is using the HYSPLIT model concentration and deposition guidance in fog situations.

  12. Russian Meteorological and Geophysical Rockets of New Generation

    Science.gov (United States)

    Yushkov, V.; Gvozdev, Yu.; Lykov, A.; Shershakov, V.; Ivanov, V.; Pozin, A.; Afanasenkov, A.; Savenkov, Yu.; Kuznetsov, V.

    2015-09-01

    To study the process in the middle and upper atmosphere, ionosphere and near-Earth space, as well as to monitor the geophysical environment in Russian Federal Service for Hydrology and Environmental Monitoring (ROSHYDROMET) the development of new generation of meteorological and geophysical rockets has been completed. The modern geophysical research rocket system MR-30 was created in Research and Production Association RPA "Typhoon". The basis of the complex MR-30 is a new geophysical sounding rocket MN-300 with solid propellant, Rocket launch takes place at an angle of 70º to 90º from the launcher, which is a farm with a guide rail type required for imparting initial rotation rocket. The Rocket is spin stabilized with a spin rate between 5 and 7 Hz. Launch weight is 1564 kg, and the mass of the payload of 50 to 150 kg. MR-300 is capable of lifting up to 300 km, while the area of dispersion points for booster falling is an ellipse with parameters 37x 60 km. The payload of the rocket MN-300 consists of two sections: a sealed, located below the instrument compartment, and not sealed, under the fairing. Block of scientific equipment is formed on the platform in a modular layout. This makes it possible to solve a wide range of tasks and conduct research and testing technologies using a unique environment of space, as well as to conduct technological experiments testing and research systems and spacecraft equipment. New Russian rocket system MERA (MEteorological Rocket for Atmospheric Research) belongs to so called "dart" technique that provide lifting of small scientific payload up to altitude 100 km and descending with parachute. It was developed at Central Aerological Observatory jointly with State Unitary Enterprise Instrument Design Bureau. The booster provides a very rapid acceleration to about Mach 5. After the burning phase of the buster the dart is separated and continues ballistic flight for about 2 minutes. The dart carries the instrument payload+ parachute

  13. European meteorological data: contribution to research, development, and policy support

    Science.gov (United States)

    Biavetti, Irene; Karetsos, Sotiris; Ceglar, Andrej; Toreti, Andrea; Panagos, Panos

    2014-08-01

    The Joint Research Centre of the European Commission has developed Interpolated Meteorological Datasets available on a regular 25x25km grid both to the scientific community and the general public. Among others, the Interpolated Meteorological Datasets include daily maximum/minimum temperature, cumulated daily precipitation, evapotranspiration and wind speed. These datasets can be accessed through a web interface after a simple registration procedure. The Interpolated Meteorological Datasets also serve the Crop Growth Monitoring System (CGMS) at European level. The temporal coverage of the datasets is more than 30 years and the spatial coverage includes EU Member States, neighboring European countries, and the Mediterranean countries. The meteorological data are highly relevant for the development, implementation and assessment of a number of European Union (EU) policy areas: agriculture, soil protection, environment, agriculture, food security, energy, climate change. An online user survey has been carried out in order to assess the impact of the Interpolated Meteorological Datasets on research developments. More than 70% of the users have used the meteorological datasets for research purposes and more than 50% of the users have used those sources as main input for their models. The usefulness of the data scored more than 70% and it is interesting to note that around 25% of the users have published their scientific outputs based on the Interpolated Meteorological Datasets. Finally, the user feedback focuses mostly on improving the data distribution process as well as the visibility of the web platform.

  14. On the early history of the Finnish Meteorological Institute

    Science.gov (United States)

    Nevanlinna, H.

    2014-03-01

    This article is a review of the foundation (in 1838) and later developments of the Helsinki (Finland) magnetic and meteorological observatory, today the Finnish Meteorological Institute (FMI). The main focus of the study is in the early history of the FMI up to the beginning of the 20th century. The first director of the observatory was Physics Professor Johan Jakob Nervander (1805-1848). He was a famous person of the Finnish scientific, academic and cultural community in the early decades of the 19th century. Finland was an autonomously part of the Russian Empire from 1809 to 1917, but the observatory remained organizationally under the University of Helsinki, independent of Russian scientific institutions, and funded by the Finnish Government. Throughout the late-19th century the Meteorological Institute was responsible of nationwide meteorological, hydrological and marine observations and research. The observatory was transferred to the Finnish Society of Sciences and Letters under the name the Central Meteorological Institute in 1881. The focus of the work carried out in the Institute was changed gradually towards meteorology. Magnetic measurements were still continued but in a lower level of importance. The culmination of Finnish geophysical achievements in the 19th century was the participation to the International Polar Year programme in 1882-1883 by setting up a full-scale meteorological and magnetic observatory in Sodankylä, Lapland.

  15. News/Press Releases

    Data.gov (United States)

    Office of Personnel Management — A press release, news release, media release, press statement is written communication directed at members of the news media for the purpose of announcing programs...

  16. Evolutionary Forecast Engines for Solar Meteorology

    Science.gov (United States)

    Coimbra, C. F.

    2012-12-01

    A detailed comparison of non-stationary regression and stochastic learning methods based on k-Nearest Neighbor (kNN), Artificial Neural Networks (ANN) and Genetic Algorithm (GA) approaches is carried out in order to develop high-fidelity solar forecast engines for several time horizons of interest. A hybrid GA/ANN method emerges as the most robust stochastic learning candidate. The GA/ANN approach In general the following decisions need to be made when creating an ANN-based solar forecast model: the ANN architecture: number of layers, numbers of neurons per layer; the preprocessing scheme; the fraction and distribution between training and testing data, and the meteorological and radiometric inputs. ANNs are very well suited to handle multivariate forecasting models due to their overall flexibility and nonlinear pattern recognition abilities. However, the forecasting skill of ANNs depends on a new set of parameters to be optimized within the context of the forecast model, which is the selection of input variables that most directly impact the fidelity of the forecasts. In a data rich scenario where irradiation, meteorological, and cloud cover data are available, it is not always evident which variables to include in the model a priori. New variables can also arise from data preprocessing such as smoothing or spectral decomposition. One way to avoid time-consuming trial-and-error approaches that have limited chance to result in optimal ANN topology and input selection is to couple the ANN with some optimization algorithm that scans the solution space and "evolves" the ANN structure. Genetic Algorithms (GAs) are well suited for this task. Results and Discussion The models built upon the historical data of 2009 and 2010 are applied to the 2011 data without modifications or retraining. We consider 3 solar variability seasons or periods, which are subsets of the total error evaluation data set. The 3 periods are defined based on the solar variability study as: - a high

  17. The Quality Control Algorithms Used in the Creation of NASA Kennedy Space Center Lightning Protection System Towers Meteorological Database

    Science.gov (United States)

    Orcutt, John M.; Brenton, James C.

    2016-01-01

    An accurate database of meteorological data is essential for designing any aerospace vehicle and for preparing launch commit criteria. Meteorological instrumentation were recently placed on the three Lightning Protection System (LPS) towers at Kennedy Space Center (KSC) launch complex 39B (LC-39B), which provide a unique meteorological dataset existing at the launch complex over an extensive altitude range. Data records of temperature, dew point, relative humidity, wind speed, and wind direction are produced at 40, 78, 116, and 139 m at each tower. The Marshall Space Flight Center Natural Environments Branch (EV44) received an archive that consists of one-minute averaged measurements for the period of record of January 2011 - April 2015. However, before the received database could be used EV44 needed to remove any erroneous data from within the database through a comprehensive quality control (QC) process. The QC process applied to the LPS towers' meteorological data is similar to other QC processes developed by EV44, which were used in the creation of meteorological databases for other towers at KSC. The QC process utilized in this study has been modified specifically for use with the LPS tower database. The QC process first includes a check of each individual sensor. This check includes removing any unrealistic data and checking the temporal consistency of each variable. Next, data from all three sensors at each height are checked against each other, checked against climatology, and checked for sensors that erroneously report a constant value. Then, a vertical consistency check of each variable at each tower is completed. Last, the upwind sensor at each level is selected to minimize the influence of the towers and other structures at LC-39B on the measurements. The selection process for the upwind sensor implemented a study of tower-induced turbulence. This paper describes in detail the QC process, QC results, and the attributes of the LPS towers meteorological

  18. Meteorological phenomena in Western classical orchestral music

    Science.gov (United States)

    Williams, P. D.; Aplin, K. L.

    2012-12-01

    The creative output of composers, writers, and artists is often influenced by their surroundings. To give a literary example, it has been claimed recently that some of the characters in Oliver Twist and A Christmas Carol were based on real-life people who lived near Charles Dickens in London. Of course, an important part of what we see and hear is not only the people with whom we interact, but also our geophysical surroundings. Of all the geophysical phenomena to influence us, the weather is arguably the most significant, because we are exposed to it directly and daily. The weather was a great source of inspiration for Monet, Constable, and Turner, who are known for their scientifically accurate paintings of the skies. But to what extent does weather inspire composers? The authors of this presentation, who are atmospheric scientists by day but amateur classical musicians by night, have been contemplating this question. We have built a systematic musical database, which has allowed us to catalogue and analyze the frequencies with which weather is depicted in a sample of classical orchestral music. The depictions vary from explicit mimicry using traditional and specialized orchestral instruments, through to subtle suggestions. We have found that composers are generally influenced by their own environment in the type of weather they choose to represent. As befits the national stereotype, British composers seem disproportionately keen to depict the UK's variable weather patterns and stormy coastline. Reference: Aplin KL and Williams PD (2011) Meteorological phenomena in Western classical orchestral music. Weather, 66(11), pp 300-306. doi:10.1002/wea.765

  19. Air concentration and ground deposition following radioactive airborne releases

    International Nuclear Information System (INIS)

    Brofferio, C.; Cagnetti, P.; Ferrara, V.

    1985-01-01

    The fundamental aim of this report is to provide the mathematical and physical operational basis for the evaluation of air concentration and ground deposition, following radioactive airborne releases from a nuclear power plant, both during normal operations and in accidental conditions. As far as accidental releases are concerned, the basical assumptions on meteorological and diffusive situation are considered from a safety point of view: namely those pessimistic but realistically representative situation are taken into account which lead to maximum air concentration and ground deposition values, even if characterized by low recurrence probability. Those elements are the inputs for many environmental transfer models of maximum consequence evaluations up to man. As far as routine releases are concerned, it is shown, together with the usual models based on long term averaged meteorological conditions, also models studied to estimate atmospheric diffusion and deposition in low wind situations and in fog conditions, being those latter very frequent in the Po valley. Finally, the main operations and modalities of collecting and elaborating meteorological data for for radioprotection evaluations are also shown. It is to be pointed out that the methods and the models developed and considered in this work are of a more general validity, and can be also used for applications concerning non-radioactive releases, as it is the case when dealing with conventional power plants

  20. Assessment of consequences from airborne releases of radioactive material

    International Nuclear Information System (INIS)

    McGrath, P.E.; Blond, R.M.

    1976-01-01

    Over the past several years, the manner in which assessments have been made of the consequences of large airborne releases of radioactive material has not changed much conceptually. The models to describe the atmospheric dispersion of the radioactive material have generally been time-invariant, i.e., the meteorological conditions (thermal stability, wind speed, and precipitation) are invariant during release and the subsequent period of radiation exposure of the population to the airborne material. The frequency distribution of the meteorological conditions are determined by analyzing several years of weather data from the appropriate geographical location. In reality, weather is continuously changing over short time periods (hours) following the release. It is to be expected that the changing meteorological conditions would have important effects on the potential consequences of the release. A time-dependent atmospheric dispersion model was developed and implemented in the Reactor Safety Study. This paper provides a description of the model and the nature of the results generated. Emphasis is given to an explanation of how, and why, these results differ from those estimated with time-invariant models

  1. EVALUATION OF METEOROLOGICAL ALERT CHAIN IN CASTILLA Y LEÓN (SPAIN): How can the meteorological risk managers help researchers?

    Science.gov (United States)

    López, Laura; Guerrero-Higueras, Ángel Manuel; Sánchez, José Luis; Matía, Pedro; Ortiz de Galisteo, José Pablo; Rodríguez, Vicente; Lorente, José Manuel; Merino, Andrés; Hermida, Lucía; García-Ortega, Eduardo; Fernández-Manso, Oscar

    2013-04-01

    Evaluating the meteorological alert chain, or, how information is transmitted from the meteorological forecasters to the final users, passing through risk managers, is a useful tool that benefits all the links of the chain, especially the meteorology researchers and forecasters. In fact, the risk managers can help significantly to improve meteorological forecasts in different ways. Firstly, by pointing out the most appropriate type of meteorological format, and its characteristics when representing the meteorological information, consequently improving the interpretation of the already-existing forecasts. Secondly, by pointing out the specific predictive needs in their workplaces related to the type of significant meteorological parameters, temporal or spatial range necessary, meteorological products "custom-made" for each type of risk manager, etc. In order to carry out an evaluation of the alert chain in Castilla y León, we opted for the creation of a Panel of Experts made up of personnel specialized in risk management (Responsible for Protection Civil, Responsible for Alert Services and Hydrological Planning of Hydrographical Confederations, Responsible for highway maintenance, and management of fires, fundamentally). In creating this panel, a total of twenty online questions were evaluated, and the majority of the questions were multiple choice or open-ended. Some of the results show how the risk managers think that it would be interesting, or very interesting, to carry out environmental educational campaigns about the meteorological risks in Castilla y León. Another result is the elevated importance that the risk managers provide to the observation data in real-time (real-time of wind, lightning, relative humidity, combined indices of risk of avalanches, snowslides, index of fires due to convective activity, etc.) Acknowledgements The authors would like to thank the Junta de Castilla y León for its financial support through the project LE220A11-2.

  2. Tornado frequency in the USA - meteorological and non-meteorological factors of a downward trend

    Directory of Open Access Journals (Sweden)

    Mihajlović Jovan

    2015-01-01

    Full Text Available Citing numerical simulations, climate alarmists believe that global warming will lead to more frequent and more intensive tornadoes. Considering temperature increase data in the contiguous USA, this study has investigated the trend of strong tornadoes in F3+ category in the 1954-2012 period. Statistically significant decrease of tornadoes per year at an average rate of 0.44 has been recorded, that is, 4.4 tornadoes per decade. Tornado increase has been recorded with F0 and F1 categories and the cause of this increase lies in meteorological and non-meteorological factors. By using upper and lower standard deviation values, the stages of tornado activity have been singled out. The 1957-1974 period may be considered as an active stage and the 1978-2009 period as an inactive stage. Upward trend of air temperature increase does not correspond with the downward trend of the number of F3+ tornado category, while the correlation coefficient between these two variables is R = −0.14. This fact does not correspond with the simulation results and output data of various numerical models anticipating an increase in the number and intensity of tornado events in the conditions of surface air temperature growth.

  3. Trends and variability of meteorological drought over the districts of ...

    Indian Academy of Sciences (India)

    4

    Keywords: Meteorological drought, standardized precipitation index, monsoon, sea ... Drought is one of the most serious problem for human societies and ecosystems. ... They found that SPI satisfactorily explains the development of conditions.

  4. Hyperion technology enables unified meteorological and radiological monitoring

    International Nuclear Information System (INIS)

    Zigic, A.; Saponjic, D.; Arandjelovic, V.; Zunic, Z. . E-mail address of corresponding author: alex@vin.bg.ac.yu; Zigic, A.)

    2005-01-01

    The present state of meteorological and radiological measurement and monitoring are quite localized to smaller areas which implies the difficulties in knowing the measurement results in the wider region instantly. The need for establishing a distributed, flexible, modular and centralized measurement system for both meteorological and radiological parameters of environment is arising. The measurement and monitoring of radiological parameters of environment are not sufficient since there is a strong correlation between radiological and meteorological parameters which implies a unified distributed automatic monitoring system. The unified monitoring system makes it possible to transfer, process and store measured data in local and central databases. Central database gives a possibility of easy access to all measured data for authorized personnel and institutions. Stored measured data in central database gives a new opportunity to create a base for meteorological and radiological modelling and studies. (author)

  5. Arctic Sea Ice Charts from Danish Meteorological Institute, 1893 - 1956

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — From 1893 to 1956, the Danish Meteorological Institute (DMI) created charts of observed and inferred sea ice extent for each summer month. These charts are based on...

  6. Meteorology observations in the Athabasca oil sands region

    International Nuclear Information System (INIS)

    1996-01-01

    Meteorological data was collected in the Athabasca oil sands area of Alberta in support of Syncrude' application for approval to develop and operate the Aurora Mine. Meteorology controls the transport and dispersion of gaseous and particulate emissions which are vented into the atmosphere. Several meteorological monitoring stations have been set up in the Fort McMurray and Fort McKay area. The study was part of Suncor's commitment to Alberta Environmental Protection to substantially reduce SO 2 emissions by July 1996. Also, as a condition of approval of the proposed Aurora Mine, the company was required to develop additional ambient air quality, sulphur deposition and biomonitoring programs. Background reports were prepared for: (1) source characterization, (2) ambient air quality observations, (3) meteorology observations, and (4) air quality monitoring. The following factors were incorporated into dispersion modelling: terrain, wind, turbulence, temperature, net radiation and mixing height, relative humidity and precipitation. 15 refs., 9 tabs., 40 figs

  7. Meteorological Data from the Russian Arctic, 1961-2000

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains monthly means of meteorological observation data from Russian stations from 1961-2000 (for most stations). The Russian station observations...

  8. Assessment of Meteorological Drought Hazard Area using GIS in ...

    African Journals Online (AJOL)

    Michael Horsfall

    The purpose of this study was to make a model of the meteorological drought hazard area using GIS. ... overlaying different hazard indicator maps in the GIS, deploying the new model. The final ..... Northeast Thailand Project Bangkok. Min. of.

  9. ISLSCP II Reanalysis Near-Surface Meteorology Data

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set for the ISLSCP Initiative II data collection provides near surface meteorological variables, fluxes of heat, moisture and momentum at the surface, and...

  10. ISLSCP II Reanalysis Near-Surface Meteorology Data

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: This data set for the ISLSCP Initiative II data collection provides near surface meteorological variables, fluxes of heat, moisture and momentum at the...

  11. Analysis of some meteorological parameters using artificial neural ...

    African Journals Online (AJOL)

    Analysis of some meteorological parameters using artificial neural network method for ... The mean daily data for sunshine hours, maximum temperature, cloud cover and ... The study used artificial neural networks (ANN) for the estimation.

  12. Meteorological safeguarding of nuclear power plant operation in Czechoslovakia

    International Nuclear Information System (INIS)

    Rak, J.; Skulec, S.

    1976-01-01

    A meteorological tower 200 m high has to be built for meteorological control of the operation of the A-1 nuclear power plant at Jaslovske Bohunice. This meteorological station will measure the physical properties of the lower layers of the atmosphere, carry out experimental verifications of the models of air pollution, investigate the effects of waste heat and waste water from the nuclear power plant on the microclimate, provide the theoretical processing of measured data with the aim of selecting the most favourable model for conditions prevailing in the Czechoslovak Socialist Republic, perform basic research of the physical properties of the ground and boundary layers of the atmosphere and the coordination of state-wide plans in the field of securing the operation of nuclear power plants with regard to meteorology. (Z.M.)

  13. CAMEX-4 DC-8 METEOROLOGICAL MEASUREMENT SYSTEM (MMS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The NASA DC-8 Meteorological Measurement System consists of three major systems: an air-motion sensing system to measure air velocity with respect to the aircraft,...

  14. CAMEX-3 DC-8 METEOROLOGICAL MEASUREMENT SYSTEM (MMS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-3 Meteorological Measurement System (MMS) dataset consists of atmospheric parameters measured by the MMS instruments aboard NASA DC-8 aircraft. The MMS...

  15. CAMEX-4 DC-8 METEOROLOGICAL MEASUREMENT SYSTEM (MMS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-4 DC-8 Meteorological Measurement System (MMS) was collected by the MMS, which consists of three major systems: an air-motion sensing system to measure air...

  16. Developing International Standards for Meteorological Balloon to Facilitate Industrial Progress

    Institute of Scientific and Technical Information of China (English)

    Deng Yizhi

    2011-01-01

    Meteorological balloon is made of natural rubber latex with a special process.On natural conditions,it carries the air sounding instrument into the high air to detect the meteorological elements in the air.As a means of delivery used in the aerological sounding,it is widely used in the meteorological,sailing,aeronautical,aerospace and other fields,and plays an extremely important role in the weather report,disaster prevention,disaster relief,guaranteeing ships and aircrafts to leave ports safely,and scientific research in relevant spaces,etc.Especially,the role of meteorological balloons is not ignorable in the forecast of extremely adverse weather frequently occurring around the world in recent years.

  17. Defense Meteorological Satellite Program (DMSP) - Space Weather Sensors

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Defense Meteorological Satellite Program (DMSP) maintains a constellation of sun-synchronous, near-polar orbiting satellites. The orbital period is 101 minutes...

  18. Meteorological fluid dynamics asymptotic modelling, stability and chaotic atmospheric motion

    CERN Document Server

    Zeytounian, Radyadour K

    1991-01-01

    The author considers meteorology as a part of fluid dynamics. He tries to derive the properties of atmospheric flows from a rational analysis of the Navier-Stokes equations, at the same time analyzing various types of initial and boundary problems. This approach to simulate nature by models from fluid dynamics will be of interest to both scientists and students of physics and theoretical meteorology.

  19. Bridging the Radiative Transfer Models for Meteorology and Solar Energy Applications

    Science.gov (United States)

    Xie, Y.; Sengupta, M.

    2017-12-01

    Radiative transfer models are used to compute solar radiation reaching the earth surface and play an important role in both meteorology and solar energy studies. Therefore, they are designed to meet the needs of specialized applications. For instance, radiative transfer models for meteorology seek to provide more accurate cloudy-sky radiation compared to models used in solar energy that are geared towards accuracy in clear-sky conditions associated with the maximum solar resource. However, models for solar energy applications are often computationally faster, as the complex solution of the radiative transfer equation is parameterized by atmospheric properties that can be acquired from surface- or satellite-based observations. This study introduces the National Renewable Energy Laboratory's (NREL's) recent efforts to combine the advantages of radiative transfer models designed for meteorology and solar energy applictions. A fast all-sky radiation model, FARMS-NIT, was developed to efficiently compute narrowband all-sky irradiances over inclined photovoltaic (PV) panels. This new model utilizes the optical preperties from a solar energy model, SMARTS, to computes surface radiation by considering all possible paths of photon transmission and the relevent scattering and absorption attenuation. For cloudy-sky conditions, cloud bidirectional transmittance functions (BTDFs) are provided by a precomputed lookup table (LUT) by LibRadtran. Our initial results indicate that FARMS-NIT has an accuracy that is similar to LibRadtran, a highly accurate multi-stream model, but is significantly more efficient. The development and validation of this model will be presented.

  20. Latin American Network of students in Atmospheric Sciences and Meteorology

    Science.gov (United States)

    Cuellar-Ramirez, P.

    2017-12-01

    The Latin American Network of Students in Atmospheric Sciences and Meteorology (RedLAtM) is a civil nonprofit organization, organized by students from Mexico and some Latin- American countries. As a growing organization, providing human resources in the field of meteorology at regional level, the RedLAtM seeks to be a Latin American organization who helps the development of education and research in Atmospheric Sciences and Meteorology in order to engage and promote the integration of young people towards a common and imminent future: Facing the still unstudied various weather and climate events occurring in Latin America. The RedLAtM emerges from the analysis and observation/realization of a limited connection between Latin American countries around research in Atmospheric Sciences and Meteorology. The importance of its creation is based in cooperation, linking, research and development in Latin America and Mexico, in other words, to join efforts and stablish a regional scientific integration who leads to technological progress in the area of Atmospheric Sciences and Meteorology. As ultimate goal the RedLAtM pursuit to develop climatic and meteorological services for those countries unable to have their own programs, as well as projects linked with the governments of Latin American countries and private companies for the improvement of prevention strategies, research and decision making. All this conducing to enhance the quality of life of its inhabitants facing problems such as poverty and inequality.

  1. Development of regional meteorological and atmospheric diffusion simulation system

    International Nuclear Information System (INIS)

    Kubota, Ryuji; Iwashige, Kengo; Kasano, Toshio

    2002-01-01

    Regional atmospheric diffusion online network (RADON) with atmospheric diffusion analysis code (ADAC) : a simulation program of diffusion of radioactive materials, volcanic ash, pollen, NOx and SOx was developed. This system can be executed in personal computer (PC) and note PC on Windows. Emission data consists of online, offline and default data. It uses the meteorology data sources such as meteorological forecasting mesh data, automated meteorological data acquisition system (AMeDAS) data, meteorological observation data in site and municipality observation data. The meteorological forecasting mesh data shows forecasting value of temperature, wind speed, wind direction and humidity in about two days. The nuclear environmental monitoring center retains the online data (meteorological data, emission source data, monitoring station data) in its PC server and can run forecasting or repeating calculation using these data and store and print out the calculation results. About 30 emission materials can be calculated simultaneously. This system can simulate a series of weather from the past and real time to the future. (S.Y.)

  2. Comparative analysis of meteorological performance of coupled chemistry-meteorology models in the context of AQMEII phase 2

    Science.gov (United States)

    Air pollution simulations critically depend on the quality of the underlying meteorology. In phase 2 of the Air Quality Model Evaluation International Initiative (AQMEII-2), thirteen modeling groups from Europe and four groups from North America operating eight different regional...

  3. Medical Meteorology: the Relationship between Meteorological Parameters (Humidity, Rainfall, Wind, and Temperature) and Brucellosis in Zanjan Province

    OpenAIRE

    Yousefali Abedini; Nahideh Mohammadi; Koorosh Kamali; Mohsen Ahadnejad; Mehdi Azari

    2016-01-01

    Background: Brucellosis (Malta fever) is a major contagious zoonotic disease, with economic and public health importance. Methods To assess the effect of meteorological (temperature, rainfall, humidity, and wind) and climate parameters on incidence of brucellosis, brucellosis distribution and meteorological zoning maps of Zanjan Province were prepared using Inverse Distance Weighting (IDW) and Kriging technique in Arc GIS medium. Zoning maps of mean temperature, rainfall, humidity, and win...

  4. Fleet Numerical Meteorology and Oceanography Center support for GODAE

    Science.gov (United States)

    Dimitriou, D.; Sharfstein, P.; Ignaszewski, M.; Clancy, M.

    2003-04-01

    The U.S. Navy's Fleet Numerical Meteorology and Oceanography Center (FNMOC; see http://www.fnmoc.navy.mil/), located in Monterey, CA, is the lead activity within the U.S. Department of Defense (DoD) for numerical weather prediction and coupled air-sea modeling. FNMOC fulfills this role through means of a suite of sophisticated global and regional meteorological and oceanographic (METOC) models, extending from the top of the atmosphere to the bottom of the ocean, which is supported by one of the world's most complete real-time METOC databases. Fleet Numerical operates around-the-clock, 365 days per year and distributes METOC products to military and civilian users around the world, both ashore and afloat, through a variety of means, including a rapidly growing and innovative use of Web technology. FNMOC's customers include all branches of the Department of Defense (DoD), other government organizations such as the National Weather Service, private companies such as the Weather Channel, a number of colleges and universities, and the general public. FNMOC acquires and processes over 6 million METOC observations per day—creating one of the world's most comprehensive real-time databases of meteorological and oceanographic observations for assimilation into its models. FNMOC employs three primary models, the Navy Operational Global Atmospheric Prediction System (NOGAPS), the Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS), and the WaveWatch III model (WW3), along with a number of specialized models and related applications. NOGAPS is a global weather model, driving nearly all other FNMOC models and applications in some fashion. COAMPS is a high-resolution regional model that has proved to be particularly valuable for forecasting weather and ocean conditions in highly complex coastal areas. WW3 is a state-of-the-art ocean wave model that is employed both globally and regionally in support of a wide variety of naval operations. Specialized models support and

  5. A 'Puff' dispersion model for routine and accidental releases

    International Nuclear Information System (INIS)

    Grsic, Z.; Rajkovic, B.; Milutinovic, P.

    1999-01-01

    A Puff dispersion model for accidental or routine releases is presented. This model was used as a constitutive part of an automatic meteorological station.All measured quantities are continuously displayed on PC monitor in a digital and graphical form, they are averaging every 10 minutes and sending to the civil information center of Belgrade. In the paper simulation of a pollutant plume dispersion from The oil refinery 'Pancevo', on April 18 th 1999 is presented. (author)

  6. Sensitivity of modeled estuarine circulation to spatial and temporal resolution of input meteorological forcing of a cold frontal passage

    Science.gov (United States)

    Weaver, Robert J.; Taeb, Peyman; Lazarus, Steven; Splitt, Michael; Holman, Bryan P.; Colvin, Jeffrey

    2016-12-01

    In this study, a four member ensemble of meteorological forcing is generated using the Weather Research and Forecasting (WRF) model in order to simulate a frontal passage event that impacted the Indian River Lagoon (IRL) during March 2015. The WRF model is run to provide high and low, spatial (0.005° and 0.1°) and temporal (30 min and 6 h) input wind and pressure fields. The four member ensemble is used to force the Advanced Circulation model (ADCIRC) coupled with Simulating Waves Nearshore (SWAN) and compute the hydrodynamic and wave response. Results indicate that increasing the spatial resolution of the meteorological forcing has a greater impact on the results than increasing the temporal resolution in coastal systems like the IRL where the length scales are smaller than the resolution of the operational meteorological model being used to generate the forecast. Changes in predicted water elevations are due in part to the upwind and downwind behavior of the input wind forcing. The significant wave height is more sensitive to the meteorological forcing, exhibited by greater ensemble spread throughout the simulation. It is important that the land mask, seen by the meteorological model, is representative of the geography of the coastal estuary as resolved by the hydrodynamic model. As long as the temporal resolution of the wind field captures the bulk characteristics of the frontal passage, computational resources should be focused so as to ensure that the meteorological model resolves the spatial complexities, such as the land-water interface, that drive the land use responsible for dynamic downscaling of the winds.

  7. Remote sensing in meteorology, oceanography and hydrology

    Energy Technology Data Exchange (ETDEWEB)

    Cracknell, A P [ed.

    1981-01-01

    Various aspects of remote sensing are discussed. Topics include: the EARTHNET data acquisition, processing, and distribution facility the design and implementation of a digital interactive image processing system geometrical aspects of remote sensing and space cartography remote sensing of a complex surface legal aspects of remote sensing remote sensing of pollution, dust storms, ice masses, and ocean waves and currents use of satellite images for weather forecasting. Notes on field trips and work-sheets for laboratory exercises are included.

  8. Radiation protection at the RA Reactor in 1998, Part -2, Annex 4, meteorology measurements

    International Nuclear Information System (INIS)

    Grsic, Z.; Adamovic, M.

    1998-01-01

    Meteorology measurements are part of the control of Institute environment, and are performed according to the regulations about methods, scope and time-limits for measuring the radioactivity levels in the vicinity of nuclear facilities. Since April 15 1997 meteorology measurements, data acquisition and processing are done by automated meteorology station. The meteorology bulletin for the Vinca Institute is completed every day by computer codes developed by the meteorology staff in the Institute. This Annex contains tables and diagrams of meteorology data collected at the special meteorology station located at the Vinca Institute [sr

  9. Radiation protection at the RA Reactor in 1999, Part -2, Annex 4, meteorology measurements

    International Nuclear Information System (INIS)

    Grsic, Z.; Adamovic, M.

    1999-01-01

    Meteorology measurements are part of the control of Institute environment, and are performed according to the regulations about methods, scope and time-limits for measuring the radioactivity levels in the vicinity of nuclear facilities. Since April 15 1997 meteorology measurements, data acquisition and processing are done by automated meteorology station. The meteorology bulletin for the Vinca Institute is completed every day by computer codes developed by the meteorology staff in the Institute. This Annex contains tables and diagrams of meteorology data collected at the special meteorology station located at the Vinca Institute [sr

  10. Radiation protection at the RA Reactor in 2000, Part 2, Annex 4, meteorology measurements

    International Nuclear Information System (INIS)

    Grsic, Z.; Adamovic, M.

    2000-01-01

    Meteorology measurements are part of the control of Institute environment, and are performed according to the regulations about methods, scope and time-limits for measuring the radioactivity levels in the vicinity of nuclear facilities. Since April 15, 1997 meteorology measurements, data acquisition and processing are done by automated meteorology station. The meteorology bulletin for the Vinca Institute is completed every day by computer codes developed by the meteorology staff in the Institute. This Annex contains tables and diagrams of meteorology data collected at the special meteorology station located at the Vinca Institute [sr

  11. Computational methods in wind power meteorology

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann Joergensen, B.; Ott, S.; Mann, J.; Badger, J.

    2006-06-15

    Subsets of measured wind data from the Hjardemael field experiment are extracted in order to produce test cases representing nearly stationary, neutral conditions with well defined upstream flow. Model solutions of the Reynolds Averaged Navier-Stokes (RANS) equations are obtained by utilizing the numerical flow solver EllipSys3D. When utilizing the well-knowh k - e model as a turbulence closure, the result is a nearly complete agreement between the measurements and the model solution - not only for the forward flow but also for the separating backward flow over the Hjardemael escarpment. Smal1 deviations can be understood from analyzing the conditions of the field experiment. It is of vital importance to understand the conditions under which the flow solver yields accurate solutions, in particular with respect to the grid generation, which was performed with the hyperbolic grid generator HypGrid2D/3D. The grid must allow the model to represent the underlying physics of the flow problem and the grid resolution must be sufficient to produce grid independent solutions. This fields not only the correct mean velocity but also the correct Turbulent Kinetic Energy (TKE). Devitations of the TKE in the zone very close to onset of separation can be understood by addressing the assumptions of a zero horizontal pressure gradient in the momentum balance near the surface. It is argued on basis of the obtained results that the model can be extended to non-neutral conditions and more complex terrain. The difficulties in using existing measurement data from a sparsely instrumented site, Porto, in complex terrain in Portugal for evaluating the model is demonstrated. Suggestions are offered to assist future field work incorporating wind measurements for complex terrain and non-neutral conditions in order to evaluate numerical flow models. (au)

  12. Meteorological Controls on Wind Turbine Wakes

    DEFF Research Database (Denmark)

    Barthelmie, Rebecca J.; Hansen, Kurt Schaldemose; Pryor, S.C.

    2013-01-01

    , modeling, and predicting this complex and interdependent system is therefore critical to understanding and modeling wind farm power losses due to wakes, and to optimizing wind farm layout. This paper quantifies the impact of these variables on the power loss due to wakes using data from the large offshore......The primary control on the magnitude of the power losses induced by wind turbine wakes in large wind farms is the hub-height wind speed via its link to the turbine thrust coefficient. Hence, at low to moderate wind speeds (between cut-in and rated turbine wind speeds) when the thrust coefficient...

  13. Integrated environmental modeling system for noble gas releases at the Savannah River Plant

    International Nuclear Information System (INIS)

    Cooper, R.E.

    1973-01-01

    The Savannah River Plant (SRP) is a large nuclear complex engaged in varied activities and is the AEC's major site for the production of weapons material. As a result of these activities, there are continuous and intermittent releases of radioactive gases to the atmosphere. Of these releases, the noble gases constitute about 11 percent of the total man-rem exposure to the population out to a distance of 100 km. Although SRP has an extensive radiological monitoring program, an environmental modeling system is necessary for adequately estimating effects on the environment. The integrated environmental modeling system in use at SRP consists of a series of computer programs that generate and use a library of environmental effects data as a function of azimuth and distance. Annual average atmospheric dispersion and azimuthal distribution of material assumed to be released as unit sources is estimated from a 2-year meteorological data base--assuming an arbitrary point of origin. The basic library of data consists of: ground-level concentrations according to isotope, and whole body gamma dose calculations that account for the total spatial distribution at discrete energy levels. These data are normalized to tritium measurements, and are subsequently used to generate similar library data that pertain to specific source locations, but always with respect to the same population grid. Thus, the total additive effects from all source points, both on- and off-site, can be estimated. The final program uses the library data to estimate population exposures for specified releases and source points for the nuclides of interest (including noble gases). Multiple source points are considered within a single pass to obtain the integrated effects from all sources

  14. Meteorological uncertainty of atmospheric dispersion model results (MUD)

    Energy Technology Data Exchange (ETDEWEB)

    Havskov Soerensen, J.; Amstrup, B.; Feddersen, H. [Danish Meteorological Institute, Copenhagen (Denmark)] [and others

    2013-08-15

    The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as possibilities for optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the 'most likely' dispersion scenario. However, recent developments in numerical weather prediction (NWP) include probabilistic forecasting techniques, which can be utilised also for long-range atmospheric dispersion models. The ensemble statistical methods developed and applied to NWP models aim at describing the inherent uncertainties of the meteorological model results. These uncertainties stem from e.g. limits in meteorological observations used to initialise meteorological forecast series. By perturbing e.g. the initial state of an NWP model run in agreement with the available observational data, an ensemble of meteorological forecasts is produced from which uncertainties in the various meteorological parameters are estimated, e.g. probabilities for rain. Corresponding ensembles of atmospheric dispersion can now be computed from which uncertainties of predicted radionuclide concentration and deposition patterns can be derived. (Author)

  15. Meteorological uncertainty of atmospheric dispersion model results (MUD)

    International Nuclear Information System (INIS)

    Havskov Soerensen, J.; Amstrup, B.; Feddersen, H.

    2013-08-01

    The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as possibilities for optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the 'most likely' dispersion scenario. However, recent developments in numerical weather prediction (NWP) include probabilistic forecasting techniques, which can be utilised also for long-range atmospheric dispersion models. The ensemble statistical methods developed and applied to NWP models aim at describing the inherent uncertainties of the meteorological model results. These uncertainties stem from e.g. limits in meteorological observations used to initialise meteorological forecast series. By perturbing e.g. the initial state of an NWP model run in agreement with the available observational data, an ensemble of meteorological forecasts is produced from which uncertainties in the various meteorological parameters are estimated, e.g. probabilities for rain. Corresponding ensembles of atmospheric dispersion can now be computed from which uncertainties of predicted radionuclide concentration and deposition patterns can be derived. (Author)

  16. Generation of typical meteorological year for different climates of China

    International Nuclear Information System (INIS)

    Jiang, Yingni

    2010-01-01

    Accurate prediction of building energy performance requires precise information of the local climate. Typical weather year files like typical meteorological year (TMY) are commonly used in building simulation. They are also essential for numerical analysis of sustainable and renewable energy systems. The present paper presents the generation of typical meteorological year (TMY) for eight typical cities representing the major climate zones of China. The data set, which includes global solar radiation data and other meteorological parameters referring to dry bulb temperature, relative humidity, wind speed, has been analyzed. The typical meteorological year is generated from the available meteorological data recorded during the period 1995-2004, using the Finkelstein-Schafer statistical method. The cumulative distribution function (CDF) for each year is compared with the CDF for the long-term composite of all the years in the period. Typical months for each of the 12 calendar months from the period of years are selected by choosing the one with the smallest deviation from the long-term CDF. The 12 typical months selected from the different years are used for the formulation of a TMY.

  17. Impact of Industrial Releases on Inshas Area

    International Nuclear Information System (INIS)

    El-Messiry, A.M.; Aly, M.M.

    1999-01-01

    Two Egyptian research reactors are located within the nuclear research center at Inshas area, 30 km north east of Cairo. This area are crowded by different industrial plants. The releases from them has a hazardous and economical effects on the research center workers and the surrounding inhabitancy. In the present work we study these effects. A meteorological regional specific data is considered all over the year, including a wind rose characterization. The study considered both normal operating conditions and an accidental releases. The results shows that there are a considerable risk due to normal releases in some areas downwind direction of the major releases, and a highly risk in areas subjected to major exposure. Regional maps of emission distribution, economical damage , pollutant concentration are obtained. The study helps to identify solutions to problems of atmospheric protection. It can be used as a decision support for the environmental, economic, and innovation planning at the national levels taking into consideration the national pollution standards and variety of existing emission sources

  18. Impact of rainstorm and runoff modeling on predicted consequences of atmospheric releases from nuclear reactor accidents

    International Nuclear Information System (INIS)

    Ritchie, L.T.; Brown, W.D.; Wayland, J.R.

    1980-05-01

    A general temperate latitude cyclonic rainstorm model is presented which describes the effects of washout and runoff on consequences of atmospheric releases of radioactive material from potential nuclear reactor accidents. The model treats the temporal and spatial variability of precipitation processes. Predicted air and ground concentrations of radioactive material and resultant health consequences for the new model are compared to those of the original WASH-1400 model under invariant meteorological conditions and for realistic weather events using observed meteorological sequences. For a specific accident under a particular set of meteorological conditions, the new model can give significantly different results from those predicted by the WASH-1400 model, but the aggregate consequences produced for a large number of meteorological conditions are similar

  19. Model variations in predicting incidence of Plasmodium falciparum malaria using 1998-2007 morbidity and meteorological data from south Ethiopia.

    Science.gov (United States)

    Loha, Eskindir; Lindtjørn, Bernt

    2010-06-16

    Malaria transmission is complex and is believed to be associated with local climate changes. However, simple attempts to extrapolate malaria incidence rates from averaged regional meteorological conditions have proven unsuccessful. Therefore, the objective of this study was to determine if variations in specific meteorological factors are able to consistently predict P. falciparum malaria incidence at different locations in south Ethiopia. Retrospective data from 42 locations were collected including P. falciparum malaria incidence for the period of 1998-2007 and meteorological variables such as monthly rainfall (all locations), temperature (17 locations), and relative humidity (three locations). Thirty-five data sets qualified for the analysis. Ljung-Box Q statistics was used for model diagnosis, and R squared or stationary R squared was taken as goodness of fit measure. Time series modelling was carried out using Transfer Function (TF) models and univariate auto-regressive integrated moving average (ARIMA) when there was no significant predictor meteorological variable. Of 35 models, five were discarded because of the significant value of Ljung-Box Q statistics. Past P. falciparum malaria incidence alone (17 locations) or when coupled with meteorological variables (four locations) was able to predict P. falciparum malaria incidence within statistical significance. All seasonal AIRMA orders were from locations at altitudes above 1742 m. Monthly rainfall, minimum and maximum temperature was able to predict incidence at four, five and two locations, respectively. In contrast, relative humidity was not able to predict P. falciparum malaria incidence. The R squared values for the models ranged from 16% to 97%, with the exception of one model which had a negative value. Models with seasonal ARIMA orders were found to perform better. However, the models for predicting P. falciparum malaria incidence varied from location to location, and among lagged effects, data

  20. Model variations in predicting incidence of Plasmodium falciparum malaria using 1998-2007 morbidity and meteorological data from south Ethiopia

    Directory of Open Access Journals (Sweden)

    Loha Eskindir

    2010-06-01

    Full Text Available Abstract Background Malaria transmission is complex and is believed to be associated with local climate changes. However, simple attempts to extrapolate malaria incidence rates from averaged regional meteorological conditions have proven unsuccessful. Therefore, the objective of this study was to determine if variations in specific meteorological factors are able to consistently predict P. falciparum malaria incidence at different locations in south Ethiopia. Methods Retrospective data from 42 locations were collected including P. falciparum malaria incidence for the period of 1998-2007 and meteorological variables such as monthly rainfall (all locations, temperature (17 locations, and relative humidity (three locations. Thirty-five data sets qualified for the analysis. Ljung-Box Q statistics was used for model diagnosis, and R squared or stationary R squared was taken as goodness of fit measure. Time series modelling was carried out using Transfer Function (TF models and univariate auto-regressive integrated moving average (ARIMA when there was no significant predictor meteorological variable. Results Of 35 models, five were discarded because of the significant value of Ljung-Box Q statistics. Past P. falciparum malaria incidence alone (17 locations or when coupled with meteorological variables (four locations was able to predict P. falciparum malaria incidence within statistical significance. All seasonal AIRMA orders were from locations at altitudes above 1742 m. Monthly rainfall, minimum and maximum temperature was able to predict incidence at four, five and two locations, respectively. In contrast, relative humidity was not able to predict P. falciparum malaria incidence. The R squared values for the models ranged from 16% to 97%, with the exception of one model which had a negative value. Models with seasonal ARIMA orders were found to perform better. However, the models for predicting P. falciparum malaria incidence varied from location

  1. Temporal variations of reference evapotranspiration and its sensitivity to meteorological factors in Heihe River Basin, China

    OpenAIRE

    Zhao, Jie; Xu, Zong-xue; Zuo, De-peng; Wang, Xu-ming

    2015-01-01

    On the basis of daily meteorological data from 15 meteorological stations in the Heihe River Basin (HRB) during the period from 1959 to 2012, long-term trends of reference evapotranspiration (ET0) and key meteorological factors that affect ET0 were analyzed using the Mann-Kendall test. The evaporation paradox was also investigated at 15 meteorological stations. In order to explore the contribution of key meteorological factors to the temporal variation of ET0, a sensitivity coefficient method...

  2. Evaluation of Savannah River Plant emergency response models using standard and nonstandard meteorological data

    International Nuclear Information System (INIS)

    Hoel, D.D.

    1984-01-01

    Two computer codes have been developed for operational use in performing real time evaluations of atmospheric releases from the Savannah River Plant (SRP) in South Carolina. These codes, based on mathematical models, are part of the SRP WIND (Weather Information and Display) automated emergency response system. Accuracy of ground level concentrations from a Gaussian puff-plume model and a two-dimensional sequential puff model are being evaluated with data from a series of short range diffusion experiments using sulfur hexafluoride as a tracer. The models use meteorological data collected from 7 towers on SRP and at the 300 m WJBF-TV tower about 15 km northwest of SRP. The winds and the stability, which is based on turbulence measurements, are measured at the 60 m stack heights. These results are compared to downwind concentrations using only standard meteorological data, i.e., adjusted 10 m winds and stability determined by the Pasquill-Turner stability classification method. Scattergrams and simple statistics were used for model evaluations. Results indicate predictions within accepted limits for the puff-plume code and a bias in the sequential puff model predictions using the meteorologist-adjusted nonstandard data. 5 references, 4 figures, 2 tables

  3. Influence of meteorological variables on diversity of plant species in Yellandu coal belt region

    Energy Technology Data Exchange (ETDEWEB)

    Prameela, K.; Singaracharya, M.A. [Kakatiya University, Warangal (India). Dept. of Botany

    2002-07-01

    Meteorological studies of the coal mining area of Yellandu in Andhra Pradesh, India during 1991-94 showed climatic fluctuations. Constant increase in temperature levels due to release of high amounts of greenhouse gases was noticed. The vigorous growth of weeds were observed during June-November and afterwards, the disappearance of these plants explained the role of rain fall in the floristic observation. Relative humidity of this area varied from 38% in May to 98% in August. Wind (1.4 km/hr min. 8.7 km/hr max) played a vital role in dispersing different coal particles in the atmosphere. The depth of water level ranged from 0.6 mt to 4.0 mt below ground level in the monsoon season and 3.0 to 14.35 mt at below ground level in summer. This meteorological data showed its influence on species diversity, biochemical processes and metabolic functioning of organisms present in ecosystem of Yellandu coal fields. 9 refs., 5 tabs.

  4. Land surface modelling in hydrology and meteorology – lessons learned from the Baltic Basin

    Directory of Open Access Journals (Sweden)

    L. P. Graham

    2000-01-01

    Full Text Available By both tradition and purpose, the land parameterization schemes of hydrological and meteorological models differ greatly. Meteorologists are concerned primarily with solving the energy balance, whereas hydrologists are most interested in the water balance. Meteorological climate models typically have multi-layered soil parameterisation that solves temperature fluxes numerically with diffusive equations. The same approach is carried over to a similar treatment of water transport. Hydrological models are not usually so interested in soil temperatures, but must provide a reasonable representation of soil moisture to get runoff right. To treat the heterogeneity of the soil, many hydrological models use only one layer with a statistical representation of soil variability. Such a hydrological model can be used on large scales while taking subgrid variability into account. Hydrological models also include lateral transport of water – an imperative if' river discharge is to be estimated. The concept of a complexity chain for coupled modelling systems is introduced, together with considerations for mixing model components. Under BALTEX (Baltic Sea Experiment and SWECLIM (Swedish Regional Climate Modelling Programme, a large-scale hydrological model of runoff in the Baltic Basin is used to review atmospheric climate model simulations. This incorporates both the runoff record and hydrological modelling experience into atmospheric model development. Results from two models are shown. A conclusion is that the key to improved models may be less complexity. Perhaps the meteorological models should keep their multi-layered approach for modelling soil temperature, but add a simpler, yet physically consistent, hydrological approach for modelling snow processes and water transport in the soil. Keywords: land surface modelling; hydrological modelling; atmospheric climate models; subgrid variability; Baltic Basin

  5. Toxics Release Inventory (TRI)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxics Release Inventory (TRI) is a dataset compiled by the U.S. Environmental Protection Agency (EPA). It contains information on the release and waste...

  6. Modeling of meteorology, chemistry and aerosol for the 2017 Utah Winter Fine Particle Study

    Science.gov (United States)

    McKeen, S. A.; Angevine, W. M.; McDonald, B.; Ahmadov, R.; Franchin, A.; Middlebrook, A. M.; Fibiger, D. L.; McDuffie, E. E.; Womack, C.; Brown, S. S.; Moravek, A.; Murphy, J. G.; Trainer, M.

    2017-12-01

    The Utah Winter Fine Particle Study (UWFPS-17) field project took place during January and February of 2017 within the populated region of the Great Salt Lake, Utah. The study focused on understanding the meteorology and chemistry associated with high particulate matter (PM) levels often observed near Salt Lake City during stable wintertime conditions. Detailed composition and meteorological observations were taken from the NOAA Twin-Otter aircraft and several surface sites during the study period, and extremely high aerosol conditions were encountered for two cold-pool episodes occurring in the last 2 weeks of January. A clear understanding of the photochemical and aerosol processes leading to these high PM events is still lacking. Here we present high spatiotemporal resolution simulations of meteorology, PM and chemistry over Utah from January 13 to February 1, 2017 using the WRF/Chem photochemical model. Correctly characterizing the meteorology is difficult due to the complex terrain and shallow inversion layers. We discuss the approach and limitations of the simulated meteorology, and evaluate low-level pollutant mixing using vertical profiles from missed airport approaches by the NOAA Twin-Otter performed routinely during each flight. Full photochemical simulations are calculated using NOx, ammonia and VOC emissions from the U.S. EPA NEI-2011 emissions inventory. Comparisons of the observed vertical column amounts of NOx, ammonia, aerosol nitrate and ammonium with model results shows the inventory estimates for ammonia emissions are low by a factor of four and NOx emissions are low by nearly a factor of two. The partitioning of both nitrate and NH3 between gas and particle phase depends strongly on the NH3 and NOx emissions to the model and calculated NOx to nitrate conversion rates. These rates are underestimated by gas-phase chemistry alone, even though surface snow albedo increases photolysis rates by nearly a factor of two. Several additional conversion

  7. Application of nonlinear forecasting techniques for meteorological modeling

    Directory of Open Access Journals (Sweden)

    V. Pérez-Muñuzuri

    2000-10-01

    Full Text Available A nonlinear forecasting method was used to predict the behavior of a cloud coverage time series several hours in advance. The method is based on the reconstruction of a chaotic strange attractor using four years of cloud absorption data obtained from half-hourly Meteosat infrared images from Northwestern Spain. An exhaustive nonlinear analysis of the time series was carried out to reconstruct the phase space of the underlying chaotic attractor. The forecast values are used by a non-hydrostatic meteorological model ARPS for daily weather prediction and their results compared with surface temperature measurements from a meteorological station and a vertical sounding. The effect of noise in the time series is analyzed in terms of the prediction results.Key words: Meterology and atmospheric dynamics (mesoscale meteorology; general – General (new fields

  8. Application of nonlinear forecasting techniques for meteorological modeling

    Directory of Open Access Journals (Sweden)

    V. Pérez-Muñuzuri

    Full Text Available A nonlinear forecasting method was used to predict the behavior of a cloud coverage time series several hours in advance. The method is based on the reconstruction of a chaotic strange attractor using four years of cloud absorption data obtained from half-hourly Meteosat infrared images from Northwestern Spain. An exhaustive nonlinear analysis of the time series was carried out to reconstruct the phase space of the underlying chaotic attractor. The forecast values are used by a non-hydrostatic meteorological model ARPS for daily weather prediction and their results compared with surface temperature measurements from a meteorological station and a vertical sounding. The effect of noise in the time series is analyzed in terms of the prediction results.

    Key words: Meterology and atmospheric dynamics (mesoscale meteorology; general – General (new fields

  9. The importance of meteorology in the environmental impacts assessment of nuclear power plants: scenarios studies using geographic information system

    International Nuclear Information System (INIS)

    Leao, I.L.B.; Biagio, R.M.S.; Costa, E.M.; Alves, R.N.

    1999-01-01

    The Brazilian Nuclear Power Plant (CNAAA) is located in a very complex region of the state of Rio de Janeiro. The environmental impact caused by the normal operation of such installation can be better evaluated by using an integrated approach, in which a geographical information system plays a very important role. In this study, environmental scenarios are integrated with some extreme and representative meteorological situations. (author)

  10. The Influence Analysis of the Rainfall Meteorological Conditions on the Operation of the Balloon Borne Radar in Plateau

    Science.gov (United States)

    Li, Qiong; Geng, Fangzhi

    2018-03-01

    Based on the characteristics of complex terrain and different seasons’ weather in Qinghai Tibet Plateau, through statistic the daily rainfall that from 2002 to 2012, nearly 11 years, by Bomi meteorological station, Bomi area rainfall forecast model is established, and which can provide the basis forecasting for dangerous weather warning system on the balloon borne radar in the next step, to protect the balloon borne radar equipment’s safety work and combat effectiveness.

  11. Coupling meteorological and hydrological models for flood forecasting

    Directory of Open Access Journals (Sweden)

    Bartholmes

    2005-01-01

    Full Text Available This paper deals with the problem of analysing the coupling of meteorological meso-scale quantitative precipitation forecasts with distributed rainfall-runoff models to extend the forecasting horizon. Traditionally, semi-distributed rainfall-runoff models have been used for real time flood forecasting. More recently, increased computer capabilities allow the utilisation of distributed hydrological models with mesh sizes from tenths of metres to a few kilometres. On the other hand, meteorological models, providing the quantitative precipitation forecast, tend to produce average values on meshes ranging from slightly less than 10 to 200 kilometres. Therefore, to improve the quality of flood forecasts, the effects of coupling the meteorological and the hydrological models at different scales were analysed. A distributed hydrological model (TOPKAPI was developed and calibrated using a 1x1 km mesh for the case of the river Po closed at Ponte Spessa (catchment area c. 37000 km2. The model was then coupled with several other European meteorological models ranging from the Limited Area Models (provided by DMI and DWD with resolutions from 0.0625° * 0.0625°, to the ECMWF ensemble predictions with a resolution of 1.85° * 1.85°. Interesting results, describing the coupled model behaviour, are available for a meteorological extreme event in Northern Italy (Nov. 1994. The results demonstrate the poor reliability of the quantitative precipitation forecasts produced by meteorological models presently available; this is not resolved using the Ensemble Forecasting technique, when compared with results obtainable with measured rainfall.

  12. Wind power variations under humid and arid meteorological conditions

    International Nuclear Information System (INIS)

    Şen, Zekâi

    2013-01-01

    Highlights: • It indicates the role of weather parameters’ roles in the wind energy calculation. • Meteorological variables are more significant in arid regions for wind power. • It provides opportunity to take into consideration air density variability. • Wind power is presented in terms of the wind speed, temperature and pressure. - Abstract: The classical wind power per rotor area per time is given as the half product of the air density by third power of the wind velocity. This approach adopts the standard air density as constant (1.23 g/cm 3 ), which ignores the density dependence on air temperature and pressure. Weather conditions are not taken into consideration except the variations in wind velocity. In general, increase in pressure and decrease in temperature cause increase in the wind power generation. The rate of increase in the pressure has less effect on the wind power as compared with the temperature rate. This paper provides the wind power formulation based on three meteorological variables as the wind velocity, air temperature and air pressure. Furthermore, from the meteorology point of view any change in the wind power is expressed as a function of partial changes in these meteorological variables. Additionally, weather conditions in humid and arid regions differ from each other, and it is interesting to see possible differences between the two regions. The application of the methodology is presented for two meteorology stations in Istanbul, Turkey, as representative of the humid regions and Al-Madinah Al-Monawwarah, Kingdom of Saudi Arabia, for arid region, both on daily record bases for 2010. It is found that consideration of air temperature and pressure in the average wind power calculation gives about 1.3% decrease in Istanbul, whereas it is about 13.7% in Al-Madinah Al-Monawwarah. Hence, consideration of meteorological variables in wind power calculations becomes more significant in arid regions

  13. Atmospheric corrosion in Gran Canaria specifically meteorological and pollution conditions

    International Nuclear Information System (INIS)

    Gonzalez, J.E.G.; Valles, M.L.; Mirza R, J.C.

    1998-01-01

    Carbon steel, copper, zinc and aluminium samples were exposed in different sizes with known ambient parameters in Gran Canaria Island and atmospheric corrosion was investigated. Weight-loss measurements used to determine corrosion damage were complemented with metallographic and XP S determination in order to characterize the structure and morphology of surface corrosion products. The ambient aggressiveness could be well evaluated from meteorological and pollution data. All atmospheric corrosion and environmental data were statistically processed for establishing general corrosion damage functions for carbon steel, copper, aluminium and zinc in terms of Gran Canaria extreme meteorological and pollution parameters. (Author)

  14. Meteorological buoy measurements in the Iceland Sea, 2007-2009

    Science.gov (United States)

    Nína Petersen, Guðrún

    2017-10-01

    The Icelandic Meteorological Office (IMO) conducted meteorological buoy measurements in the central Iceland Sea in the time period 2007-2009, specifically in the northern Dreki area on the southern segment of the Jan Mayen Ridge. Due to difficulties in deployment and operations, in situ measurements in this region are sparse. Here the buoy, deployment and measurements are described with the aim of giving a future user of the data set information that is as comprehensive as possible. The data set has been quality-checked, suspect data removed and the data set made publicly available from PANGAEA Data Publisher (PANGAEA.876206" target="_blank">https://doi.org/10.1594/PANGAEA.876206).

  15. Barrier island forest ecosystem: role of meteorologic nutrient inputs.

    Science.gov (United States)

    Art, H W; Bormann, F H; Voigt, G K; Woodwell, G M

    1974-04-05

    The Sunken Forest, located on Fire Island, a barrier island in the Atlantic Ocean off Long Island, New York, is an ecosystem in which most of the basic cation input is in the form of salt spray. This meteorologic input is sufficient to compensate for the lack of certain nutrients in the highly weathered sandy soils. In other ecosystems these nutrients are generally supplied by weathering of soil particles. The compensatory effect of meteorologic input allows for primary production rates in the Sunken Forest similar to those of inland temperate forests.

  16. Natural radioactive environmental pollution and meteorological characteristics of Faisalabad environment

    International Nuclear Information System (INIS)

    Shahid, M.A.K.; Sharif, R.; Hussain, K.

    1999-01-01

    This study is about Faisalabad, the third largest and industrial city of Pakistan, where the maximum temperature in summer reaches up to 50 deg. C and in winter it may fall below the freezing point. In this study on attempt has been made to find co-relation between local weather conditions and natural radioactive concentrations. The natural radioactivity was found to have no co-relation with meteorological parameters. Thus the natural activity is independent of meteorological characteristics, which confirms the random nature of radioactivity. (author)

  17. Numerical simulation of meteorological conditions for peak pollution in Paris

    Energy Technology Data Exchange (ETDEWEB)

    Carissimo, B. [Electricite de France (EDF), 78 - Chatou (France). Direction des Etudes et Recherches

    1997-06-01

    Results obtained on the simulation of meteorological conditions during two episodes of peak pollution in Paris are presented, one in the winter, the other in the summer. The A3UR air quality modelling system is first described followed by the MERCURE mesoscale meteorological model. The conditions of simulation are described. The results obtained on these two causes show satisfactory agreement, for example on the magnitude of the urban heat island which is correctly reproduced. In this study, several areas of progress have been identified: improvement of the altitude measurement network around cities, the simulation of light wind conditions and the simulation of formation and dissipation of fog. (author) 24 refs.

  18. Towards A Grid Infrastructure For Hydro-Meteorological Research

    Directory of Open Access Journals (Sweden)

    Michael Schiffers

    2011-01-01

    Full Text Available The Distributed Research Infrastructure for Hydro-Meteorological Study (DRIHMS is a coordinatedaction co-funded by the European Commission. DRIHMS analyzes the main issuesthat arise when designing and setting up a pan-European Grid-based e-Infrastructure for researchactivities in the hydrologic and meteorological fields. The main outcome of the projectis represented first by a set of Grid usage patterns to support innovative hydro-meteorologicalresearch activities, and second by the implications that such patterns define for a dedicatedGrid infrastructure and the respective Grid architecture.

  19. Multivariate analysis between air pollutants and meteorological variables in Seoul

    International Nuclear Information System (INIS)

    Kim, J.; Lim, J.

    2005-01-01

    Multivariate analysis was conducted to analyze the relationship between air pollutants and meteorological variables measured in Seoul from January 1 to December 31, 1999. The first principal component showed the contrast effect between O 3 and the other pollutants. The second principal component showed the contrast effect between CO, SO 2 , NO 2 , and O 3 , PM 10 , TSP. Based on the cluster analysis, three clusters represented different air pollution levels, seasonal characteristics of air pollutants, and meteorological conditions. Discriminant analysis with air environment index (AEI) was carried out to develop an air pollution index function. (orig.)

  20. ROMANIAN AERONAUTICAL METEOROLOGY APPLICABLE LEGAL FRAMEWORK –BRIEFING

    Directory of Open Access Journals (Sweden)

    CATALIN POPA

    2012-05-01

    Full Text Available The purpose of this briefing is toprovide an overview of the aeronautical meteorology legal framework in Romania. In this context, the role and importance of aeronautical meteorology in international air traffic management will be underlined, with focus on the civil aviation activity in Romania. The international legal framework and modalities of implementing these rules at national level will constitute a significant part of the present study., Specific accent will be put on the national regulatory framework and structure, means of updating it, and how it responds to changing regulatory requirements.

  1. Kaiseraugst nuclear power station: meteorological effects of the cooling towers

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    Considerations of water conservation persuaded the German Government in 1971 not to allow the use of the Aar and Rhine for direct cooling of nuclear power stations. The criticism is often made that the Kaiseraugst cooling towers were built without full consideration of the resulting meteorological effects. The criticism is considered unjustified because the Federal Cooling Tower Commission considered all the relevant aspects before making its recommendations in 1972. Test results and other considerations show that the effect of the kaiseraugst cooling towers on meteorological and climatic conditions is indeed minimal and details are given. (P.G.R.)

  2. Application of meteorology to safety at nuclear plants

    International Nuclear Information System (INIS)

    1968-01-01

    This report was prepared on behalf of the International Atomic Energy Agency by an international panel of experts who met at the Agency's headquarters from 10 to 14 April 1967. The application of meteorology to safety at nuclear plants is discussed in connection with site selection, design and construction, operation, and emergency planning and action. The final chapter considers the training to be given to operators and health and safety personnel on meteorology problems. The appendix gives a simple method for computing air concentration values at ground level. An extensive bibliography is also included.

  3. Inherent uncertainties in meteorological parameters for wind turbine design

    Science.gov (United States)

    Doran, J. C.

    1982-01-01

    Major difficulties associated with meteorological measurments such as the inability to duplicate the experimental conditions from one day to the next are discussed. This lack of consistency is compounded by the stochastic nature of many of the meteorological variables of interest. Moreover, simple relationships derived in one location may be significantly altered by topographical or synoptic differences encountered at another. The effect of such factors is a degree of inherent uncertainty if an attempt is made to describe the atmosphere in terms of universal laws. Some of these uncertainties and their causes are examined, examples are presented and some implications for wind turbine design are suggested.

  4. Abstraction the public from scientific - applied meteorological-climatologic data

    Science.gov (United States)

    Trajanoska, L.

    2010-09-01

    Mathematical and meteorological statistic processing of meteorological-climatologic data, which includes assessment of the exactness, level of confidence of the average and extreme values, frequencies (probabilities) of the occurrence of each meteorological phenomenon and element e.t.c. helps to describe the impacts climate may have on different social and economic activities (transportation, heat& power generation), as well as on human health. Having in mind the new technology and the commercial world, during the work with meteorological-climatologic data we have meet many different challenges. Priority in all of this is the quality of the meteorological-climatologic set of data. First, we need compatible modern, sophisticated measurement and informatics solution for data. Results of this measurement through applied processing and analyze is the second branch which is very important also. Should we all (country) need that? Today we have many unpleasant events connected with meteorology, many questions which are not answered and all of this has too long lasting. We must give the answers and solve the real and basic issue. In this paper the data issue will be presented. We have too much of data but so little of real and quality applied of them, Why? There is a data for: -public applied -for jurisdiction needs -for getting fast decision-solutions (meteorological-dangerous phenomenon's) -for getting decisions for long-lasting plans -for explore in different sphere of human living So, it is very important for what kind of data we are talking. Does the data we are talking are with public or scientific-applied character? So,we have two groups. The first group which work with the data direct from the measurement place and instrument. They are store a quality data base and are on extra help to the journalists, medical workers, human civil engineers, electromechanical engineers, agro meteorological and forestry engineer e.g. The second group do work with all scientific

  5. Effects of nearby surface features on wind speed at a nuclear plant meteorological station

    International Nuclear Information System (INIS)

    Nielsen, N.A.; Goodwin, R.J.; Pittman, D.E.

    1984-01-01

    There is a definite cause and effect relationship between the trees in the vicinity of the meteorological tower and the wind speed at the 10-meter level on the meteorological tower. For the affected directions, horizontal wind speed is significantly reduced below what it would be for that level if the trees were not present. This effect is only slightly less for the 10:1 exposure achieved with the 1977 tree clearing, which illustrates that meeting this commonly accepted distance to height ratio does not assure representativeness of 10-meter data collected at a nuclear plant site. The somewhat stronger effect for winds from the south through southwest directions may be partly attributable to the abrupt change in roughness and elevation encountered by air moving at an angle or directly across the reservoir, which is 3.5 to 5.0 kilometers wide at this site. This general reduction in wind speed values below what would be expected at the plant location will result in biased dispersion estimates. Calculated relative concentration values for releases treated as ground-level or building-wake releases would be larger than actual concentrations. While this would provide conservative concentration values, radioactive plume transport calculations would be nonconservative. The calculated, or predicted, transport rate would be slower than the actual transport rate. Such local biases affecting the spatial representativeness of airflow at 10 meters are a primary reason for TVA's decision to use 46-meter wind data for ground-level transport and diffusion modeling in its radiological emergency preparedness program

  6. A study of the atmospheric dispersion of a high release of krypton-85 above a complex coastal terrain, comparison with the predictions of Gaussian models (Briggs, Doury, ADMS4).

    Science.gov (United States)

    Leroy, C; Maro, D; Hébert, D; Solier, L; Rozet, M; Le Cavelier, S; Connan, O

    2010-11-01

    Atmospheric releases of krypton-85, from the nuclear fuel reprocessing plant at the AREVA NC facility at La Hague (France), were used to test Gaussian models of dispersion. In 2001-2002, the French Institute for Radiological Protection and Nuclear Safety (IRSN) studied the atmospheric dispersion of 15 releases, using krypton-85 as a tracer for plumes emitted from two 100-m-high stacks. Krypton-85 is a chemically inert radionuclide. Krypton-85 air concentration measurements were performed on the ground in the downwind direction, at distances between 0.36 and 3.3 km from the release, by neutral or slightly unstable atmospheric conditions. The standard deviation for the horizontal dispersion of the plume and the Atmospheric Transfer Coefficient (ATC) were determined from these measurements. The experimental results were compared with calculations using first generation (Doury, Briggs) and second generation (ADMS 4.0) Gaussian models. The ADMS 4.0 model was used in two configurations; one takes account of the effect of the built-up area, and the other the effect of the roughness of the surface on the plume dispersion. Only the Briggs model correctly reproduced the measured values for the width of the plume, whereas the ADMS 4.0 model overestimated it and the Doury model underestimated it. The agreement of the models with measured values of the ATC varied according to distance from the release point. For distances less than 2 km from the release point, the ADMS 4.0 model achieved the best agreement between model and measurement; beyond this distance, the best agreement was achieved by the Briggs and Doury models.

  7. Atmospheric dilution factors for radioactive releases from Inshas research reactor, Egypt

    International Nuclear Information System (INIS)

    Abdel Aal, M.M.; Aly, A.I.M.; Tawfik, F.S.

    1994-01-01

    In the frame of assessing the suitability of Inshas site for constructing a new research reactor 20 MW, the meteorological condition are analyzed to determine the most affected population sectors. The atmospheric stability classes are estimated by a developed computer program in which the meteorological data for one year are used as input data. The results indicate that stability class F (moderately stable) is predominant one. The dilution factor is calculated using the computer code XOQDOQ for meteorological evaluation of routine effluent releases at nuclear power stations, which implements regulatory Guide 1.111 for both normal and desert conditions and for ground and elevated releases. The concentration isopleths are plotted and the most affected sector is the southern one with higher values for desert condition than the corresponding normal condition at same distance from the source. 4 fig., 3 tab

  8. EarthLabs - Investigating Hurricanes: Earth's Meteorological Monsters

    Science.gov (United States)

    McDaris, J. R.; Dahlman, L.; Barstow, D.

    2007-12-01

    Earth science is one of the most important tools that the global community needs to address the pressing environmental, social, and economic issues of our time. While, at times considered a second-rate science at the high school level, it is currently undergoing a major revolution in the depth of content and pedagogical vitality. As part of this revolution, labs in Earth science courses need to shift their focus from cookbook-like activities with known outcomes to open-ended investigations that challenge students to think, explore and apply their learning. We need to establish a new model for Earth science as a rigorous lab science in policy, perception, and reality. As a concerted response to this need, five states, a coalition of scientists and educators, and an experienced curriculum team are creating a national model for a lab-based high school Earth science course named EarthLabs. This lab course will comply with the National Science Education Standards as well as the states' curriculum frameworks. The content will focus on Earth system science and environmental literacy. The lab experiences will feature a combination of field work, classroom experiments, and computer access to data and visualizations, and demonstrate the rigor and depth of a true lab course. The effort is being funded by NOAA's Environmental Literacy program. One of the prototype units of the course is Investigating Hurricanes. Hurricanes are phenomena which have tremendous impact on humanity and the resources we use. They are also the result of complex interacting Earth systems, making them perfect objects for rigorous investigation of many concepts commonly covered in Earth science courses, such as meteorology, climate, and global wind circulation. Students are able to use the same data sets, analysis tools, and research techniques that scientists employ in their research, yielding truly authentic learning opportunities. This month-long integrated unit uses hurricanes as the story line by

  9. Regional applicability of seven meteorological drought indices in China

    Institute of Scientific and Technical Information of China (English)

    YANG Qing; LI MingXing; ZHENG ZiYan; MA ZhuGuo

    2017-01-01

    The definition of a drought index is the foundation of drought research.However,because of the complexity of drought,there is no a unified drought index appropriate for different drought types and objects at the same time.Therefore,it is crucial to determine the regional applicability of various drought indices.Using terrestrial water storage obtained from the Gravity Recovery And Climate Experiment,and the observed soil moisture and streamflow in China,we evaluated the regional applicability of seven meteorological drought indices:the Palmer Drought Severity Index(PDSI),modified PDSI(PDSI_CN) based on observations in China,self-calibrating PDSI(scPDSI),Surface Wetness Index(SWI),Standardized Precipitation Index(SPI),Standardized Precipitation Evapotranspiration Index(SPEI),and soil moisture simulations conducted using the community land model driven by observed atmospheric forcing(CLM3.5/ObsFC).The results showed that the scPDSI is most appropriate for China.However,it should be noted that the scPDSI reduces the value range slightly compared with the PDSI and PDSI_CN;thus,the classification of dry and wet conditions should be adjusted accordingly.Some problems might exist when using the PDSI and PDSI_CN in humid and arid areas because of the unsuitability of empiricalparameters.The SPI and SPEI are more appropriate for humid areas than arid and semiarid areas.This is because contributions of temperature variation to drought are neglected in the SPI,but overestimated in the SPEI,when potential evapotranspiration is estimated by the Thornthwaite method in these areas.Consequently,the SPI and SPEI tend to induce wetter and drier results,respectively.The CLM3.5/ObsFC is suitable for China before 2000,but not for arid and semiarid areas after 2000.Consistent with other drought indices,the SWI shows similar interannual and decadal change characteristics in detecting annual dry/wet variations.Although the long-term trends of drought areas in China detected by these seven

  10. Prospects of application of survey satellite image for meteorology

    Science.gov (United States)

    Kapochkina, A. B.; Kapochkin, B. B.; Kucherenko, N. V.

    The maximal interest is represented with the information from geostationary satellites. These satellites repeat shootings the chosen territories, allowing to study dynamics of images. Most interesting shootings in IR a range. Studying of survey image is applied to studying linear elements of clouds (LEC). It is established, that "LEC " arise only above breaks of an earth's crust. In research results of the complex analysis of the satellite data, hydrometeorological supervision, seismicity, supervision over deformations of a surface of the Earth are used. It is established that before formation "LEC " in a ground layer arise anomalies of temperature and humidity. The situation above Europe 16 May, 2001 is considered. "LEC " in Europe block carry of air weights from the west to the east. Synoptic conditions above the Great Britain July, 7-10, 2000 is considered. Moving "LEC" trace distribution of deformation waves to an earth's crust. Satellite shootings Europe before earthquake in Greece 14.08.2003 are considered. These days ground supervision were conducted and the data of the geostationary satellite were analyzed. During moving "LEC " occur failures (destruction houses & of gas mains), earthquake. The situation above Iberian peninsula 12-16.11.2001 is considered. "LEC" arose before flooding in Europe. The situation before flooding in Germany June, 6-8, 2002 and flooding on the river Kuban June, 16-23, 2002 is considered. In case of occurrence of tectonic compression of an earth's crust there are "LEC ", tracer intensive movements of air upwards and downwards above negative and positive anomalies of the form of a terrestrial surface, accordingly. Such meteorological situations are dangerous to flights of aircraft, the fast gravitational anomalies influencing into orbits of movement of satellites trace. The situation above equatorial Atlantic 26.03.2003 years is considered. At tectonic compression of continental scale overcast covers the whole continents for more

  11. Sorghum yield and associated satellite-derived meteorological ...

    African Journals Online (AJOL)

    Sorghum yield and associated satellite-derived meteorological parameters in semi-arid Botswana. ... African Crop Science Journal ... Sorghum (Sorghum bicolor) yield for five seasons (2005/6 to 2009/10) from the Botswana Department of Crop ... Key Words: Coefficient of determination, NDVI, Pearson correlation ...

  12. Mesoscale meteorological model based on radioactive explosion cloud simulation

    International Nuclear Information System (INIS)

    Zheng Yi; Zhang Yan; Ying Chuntong

    2008-01-01

    In order to simulate nuclear explosion and dirty bomb radioactive cloud movement and concentration distribution, mesoscale meteorological model RAMS was used. Particles-size, size-active distribution and gravitational fallout in the cloud were considered. The results show that the model can simulate the 'mushroom' clouds of explosion. Three-dimension fluid field and radioactive concentration field were received. (authors)

  13. Meteorology and Wind Energy Department annual report 1996

    Energy Technology Data Exchange (ETDEWEB)

    Hauge Madsen, P.; Dannemand Andersen, P.; Skrumsager, B. [eds.

    1997-07-01

    In 1996 the Meteorology and Wind Energy Department has performed research within the programme areas: (1) wind energy and (2) atmospheric processes. The objectives are through research in boundary layer meteorology, fluid dynamics, aerodynamics and structural mechanics to contribute with new knowledge within (1) wind energy in relation to development, manufacturing, operation and export as well as testing and certification of wind turbines, and (2) aspects of boundary-layer meteorology related to environmental and energy problems of society. The work is supported by the research programs of the Ministry of Environment and Energy, the Nordic Council of Ministers, EU as well as by industry. Through our research and development work we develop and provide methodologies including computer models for use by industry, institutions, and governmental authorities. In the long view we are developing facilities and programs enabling us to serve as a national and European centre for wind-energy and boundary-layer meteorological research. A summary of our activities in 1996 is presented. (au) 4 tabs., 5 ills.

  14. Seasonal variation of meteorological factors on air parameters and ...

    African Journals Online (AJOL)

    The impacts of gas flaring on meteorological factors at Ibeno, Eket, Onna, Esit Eket and Umudike - Nigeria were investigated by measuring air quality parameters. The results show that the mean concentration of air parameters value were below Federal Environmental Protection Agency (FEPA) and United States ...

  15. design, construction and evaluation of a meteorological mobile mast

    African Journals Online (AJOL)

    Vincent

    gathering meteorological information through the use of radiosondes [3]. Earlier measurements of wind and air pressure were done by launching balloons which climb through the denser air close to the earth to the thinner air in the upper atmosphere and the instruments carried collect data about wind in the different layers ...

  16. Effects of meteorological factors on the incidence of meningococcal ...

    African Journals Online (AJOL)

    Background and Objectives: Substantial climate changes have led to the emergence and re-emergence of various infectious diseases worldwide, presenting an imperative need to explore the effects of meteorological factors on serious contagious disease incidences such as that of meningococcal meningitis (MCM).

  17. The Effect of Meteorological Factors on the Population Dynamics of ...

    African Journals Online (AJOL)

    Michael Horsfall

    Regression equations of fly incidence with all the meteorological parameters were also determined. Results of the present investigation may be utilized in chalking out sustainable pest management strategy in the agro-ecological system under consideration. @ JASEM. Fruit flies are important pests of fruits, vegetables and.

  18. Thermometric convection coefficients for rocket meteorological sensors (tables)

    Science.gov (United States)

    Staffanson, F. L.

    1974-01-01

    Values of the convective heat transfer coefficient h, and the recovery factor r, for miniature beads, fine wires, and films in rarefied air flow are shown. Data provide a standard reference for computing consistent operational corrections to rocket meteorological measurements, and for predicting the performance of existing and proposed sensor systems.

  19. Influence of the Meteorology Mast on a Cup Anemometer

    DEFF Research Database (Denmark)

    Hansen, Martin O. L.; Pedersen, B.M.

    1999-01-01

    The actuator disc model is applied on lattice-type meteorological masts to estimate the influence of the tower on the accuracy of the measured wind speed. Combining the results with corrections for the boom, on which the anemometer is mounted, good agreement is found for measurements made on the ...

  20. Mutual Coupling Between Meteorological Parameters and Secondary Microseisms

    Czech Academy of Sciences Publication Activity Database

    Holub, Karel; Kalenda, Pavel; Rušajová, Jana

    2013-01-01

    Roč. 24, č. 6 (2013), s. 933-949 ISSN 1017-0839 R&D Projects: GA MŠk LM2010008 Institutional support: RVO:68145535 ; RVO:67985891 Keywords : secondary microseisms * meteorological elements * statistics Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.061, year: 2013 http://tao.cgu.org.tw/pdf/v246p933.pdf