WorldWideScience

Sample records for released policy directive

  1. Gliclazide directly inhibits arginine-induced glucagon release

    DEFF Research Database (Denmark)

    Cejvan, Kenan; Coy, David H; Holst, Jens Juul

    2002-01-01

    Arginine-stimulated insulin and somatostatin release is enhanced by the sulfonylurea gliclazide. In contrast, gliclazide inhibits the glucagon response. The aim of the present study was to investigate whether this inhibition of glucagon release was mediated by a direct suppressive effect of glicl......Arginine-stimulated insulin and somatostatin release is enhanced by the sulfonylurea gliclazide. In contrast, gliclazide inhibits the glucagon response. The aim of the present study was to investigate whether this inhibition of glucagon release was mediated by a direct suppressive effect....... In islet perifusions with DC-41-33, arginine-induced glucagon release was inhibited by 66%. We therefore concluded that gliclazide inhibits glucagon release by a direct action on the pancreatic A cell....

  2. Sustained Release of a Water-Soluble Drug from Directly ...

    African Journals Online (AJOL)

    Okra gum was evaluated as a controlled-release agent in modified release matrices in comparison with sodium carboxymethylcellulose (NaCMC) using aspirin as the model drug. Tablets were produced by direct compression and the in vitro drug release was assessed under conditions similar to those in the gastrointestinal ...

  3. Sustained Release of a Watermgoluble tiring from Directly ...

    African Journals Online (AJOL)

    Sustained Release of a Watermgoluble tiring from Directly Compressed Okra Gum Matrix. Tablets. Val). Mill, MA. Gilllllbll'ifl'l' AND KT. ... in near noromorder release of aspirin from the matrix tablets. The results indicate that okra gum is .... porous structure including alteration of the shape and size distribution of the pores.

  4. Direct releases to the surface and associated complementary cumulative distribution functions in the 1996 performance assessment for the Waste Isolation Pilot Plant: direct brine release

    International Nuclear Information System (INIS)

    Stoelzel, D.M.; O'Brien, D.G.; Garner, J.W.; Helton, J.C.; Johnson, J.D.; Smith, L.N.

    2000-01-01

    The following topics related to the treatment of direct brine releases to the surface environment in the 1996 performance assessment for the Waste Isolation Pilot Plant (WIPP) are presented: (i) mathematical description of models; (ii) uncertainty and sensitivity analysis results arising from subjective (i.e. epistemic) uncertainty for individual releases; (iii) construction of complementary cumulative distribution functions (CCDFs) arising from stochastic (i.e. aleatory) uncertainty; and (iv) uncertainty and sensitivity analysis results for CCDFs. The presented analyses indicate that direct brine releases do not constitute a serious threat to the effectiveness of the WIPP as a disposal facility for transuranic waste. Even when the effects of uncertain analysis inputs are taken into account, the CCDFs for direct brine releases fall substantially to the left of the boundary line specified in the US Environmental Protection Agency's standard for the geologic disposal of radioactive waste (40 CFR 191, 40 CFR 194)

  5. 14 CFR 1213.102 - Policy.

    Science.gov (United States)

    2010-01-01

    ... INFORMATION MEDIA § 1213.102 Policy. (a) NASA, a scientific and technical Agency, is committed to a culture of... culture of openness, NASA employees may, consistent with this policy, speak to the press and the public... Policy Directives). Examples of information not releasable under this policy include, without limitation...

  6. Effectiveness Of Foreign Direct Investment Policy In Nigeria (1986 ...

    African Journals Online (AJOL)

    The paper dwells on an investigation of the effectiveness of foreign direct investment policy in Nigeria. Employing the ordinary least square regression technique, the null hypothesis of no significant relationship between foreign direct investment policy measures and foreign direct investment was tested. The null hypothesis ...

  7. Transient fission gas release during direct electrical heating experiments

    International Nuclear Information System (INIS)

    Fenske, G.R.; Emerson, J.E.; Savoie, F.E.

    1983-12-01

    The gas release behavior of irradiated EBR-II fuel was observed to be dependent on several factors: the presence of cladding, the retained gas content, and the energy absorbed. Fuel that retained in excess of 16 to 17 μmoles/g of fission gas underwent spallation as the cladding melted and released 22 to 45% of its retained gas, while fuel with retained gas levels below approx. 15 to 16 μmoles/g released less than approx. 9% of its gas as the cladding melted. During subsequent direct electrical heating ramps, fuel that did not spall released an additional quantity of gas (up to 4 μmoles/g), depending on the energy absorbed

  8. Directed Technical Change and Economic Growth Effects of Environmental Policy

    DEFF Research Database (Denmark)

    Kruse-Andersen, Peter Kjær

    2016-01-01

    A Schumpeterian growth model is developed to investigate how environmental policy affects economic growth when environmental policy also affects the direction of technical change. In contrast to previous models, production and pollution abatement technologies are embodied in separate intermediate...... unambiguously directs research efforts toward pollution abatement technologies and away from production technologies. This directed technical change reduces economic growth and pollution emission growth. Simulation results indicate that even large environmental policy reforms have small economic growth effects....... However, these economic growth effects have relatively large welfare effects which suggest that static models and exogenous growth models leave out an important welfare effect of environmental policy....

  9. 77 FR 46805 - Small Business Innovation Research Program Policy Directive

    Science.gov (United States)

    2012-08-06

    ... Vol. 77 Monday, No. 151 August 6, 2012 Part II Small Business Administration 13 CFR Chapter I Small Business Innovation Research Program Policy Directive; Small Business Technology Transfer Program Policy Directive; Small Business Innovation Research (SBIR) Program and Small Business Technology...

  10. 77 FR 46855 - Small Business Technology Transfer Program Policy Directive

    Science.gov (United States)

    2012-08-06

    ... SMALL BUSINESS ADMINISTRATION 13 CFR Chapter I RIN 3245-AF45 Small Business Technology Transfer Program Policy Directive AGENCY: Small Business Administration. ACTION: Final policy directive with request for comments. SUMMARY: The U.S. Small Business Administration (SBA) is amending its Small Business...

  11. 75 FR 15756 - Small Business Innovation Research Program Policy Directive

    Science.gov (United States)

    2010-03-30

    ... SMALL BUSINESS ADMINISTRATION RIN 3244-AF61 Small Business Innovation Research Program Policy Directive AGENCY: U.S. Small Business Administration. ACTION: Notice of Final Amendments to Policy Directive. SUMMARY: This document announces a final amendment to the Small Business Innovation Research (SBIR...

  12. Application of innovative policies for controlling radionuclide releases: The open-quotes open-market trading ruleclose quotes

    International Nuclear Information System (INIS)

    Moeller, D.W.

    1997-01-01

    In the past, most efforts for reducing airborne radio nuclide releases and controlling radioactive wastes have been directed to the development of new and improved technologies. Little attention has been paid to the possible application to these problems of new, innovative policies. Yet, experience in other fields shows that such applications could be beneficial. A prime example is the open-quotes open-market trading rule,close quotes now being widely used in the U.S. for the control of a range of environmental problems. Through this rule, nuclear facility operators would be permitted to control airborne emissions in a more cost-effective manner, and those responsible for decommissioning and decontaminating nuclear facilities no longer in operation could do so at far lower costs while generating significantly smaller volumes of radioactive wastes. Application of such a policy would also significantly reduce the demands on existing, and the need for research to develop new, improved, control technologies. 16 refs

  13. 43 CFR 2.2 - What is DOI's policy regarding release of records under the FOIA?

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What is DOI's policy regarding release of... RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT General Information § 2.2 What is DOI's policy regarding... public consistent with the spirit of the FOIA and the Privacy Act. ...

  14. Directed Technical Change and Climate Policy

    NARCIS (Netherlands)

    Otto, V.M.; Löschel, A.; Reilly, J.

    2006-01-01

    This paper studies the cost effectiveness of climate policy if there are technology externalities. For this purpose, we develop a forward-looking CGE model that captures empirical links between CO2 emissions associated with energy use, directed technical change and the economy. We find the

  15. Application of innovative policies for controlling radionuclide releases: The {open_quotes}open-market trading rule{close_quotes}

    Energy Technology Data Exchange (ETDEWEB)

    Moeller, D.W. [Dade Moeller & Associates, Inc., New Bern, NC (United States)

    1997-08-01

    In the past, most efforts for reducing airborne radio nuclide releases and controlling radioactive wastes have been directed to the development of new and improved technologies. Little attention has been paid to the possible application to these problems of new, innovative policies. Yet, experience in other fields shows that such applications could be beneficial. A prime example is the {open_quotes}open-market trading rule,{close_quotes} now being widely used in the U.S. for the control of a range of environmental problems. Through this rule, nuclear facility operators would be permitted to control airborne emissions in a more cost-effective manner, and those responsible for decommissioning and decontaminating nuclear facilities no longer in operation could do so at far lower costs while generating significantly smaller volumes of radioactive wastes. Application of such a policy would also significantly reduce the demands on existing, and the need for research to develop new, improved, control technologies. 16 refs.

  16. Directed Security Policies: A Stateful Network Implementation

    Directory of Open Access Journals (Sweden)

    Cornelius Diekmann

    2014-05-01

    Full Text Available Large systems are commonly internetworked. A security policy describes the communication relationship between the networked entities. The security policy defines rules, for example that A can connect to B, which results in a directed graph. However, this policy is often implemented in the network, for example by firewalls, such that A can establish a connection to B and all packets belonging to established connections are allowed. This stateful implementation is usually required for the network's functionality, but it introduces the backflow from B to A, which might contradict the security policy. We derive compliance criteria for a policy and its stateful implementation. In particular, we provide a criterion to verify the lack of side effects in linear time. Algorithms to automatically construct a stateful implementation of security policy rules are presented, which narrows the gap between formalization and real-world implementation. The solution scales to large networks, which is confirmed by a large real-world case study. Its correctness is guaranteed by the Isabelle/HOL theorem prover.

  17. BULGARIAN EMPLOYMENT POLICY: PRIORITIES AND DIRECTIONS 2017

    Directory of Open Access Journals (Sweden)

    Ekaterina Arabska

    2017-04-01

    Full Text Available Development of labor market and employment policy in Bulgaria in contemporary dynamic conditions of social and economic life is in close relation to the European policies and programs and the needs of creating conditions for raising the level of employability of some special target groups on the labor market determined as the most vulnerable and needing particular measures of support. Current study makes analyses of priorities and directions in Bulgarian national employment policy for 2017 as set into the National action plan on employment considering a number of strategic and legislative documents on both national and European level. The general conclusions are focused on the systematization of actions and the importance of social dialogue.

  18. STRATEGIC DIRECTIONS FOR REFORMING FISCAL POLICY OF UKRAINE

    Directory of Open Access Journals (Sweden)

    Тymoshenko A.

    2018-01-01

    Full Text Available The article is about the current direction of the transformation of the Ukrainian fiscal policy. The analysis of tax revenues to the State Budget and expenditures from it was carried out. Negative trends in the implementation of fiscal policy have been identified. A mechanism for implementing the fiscal policy is proposed. The main strategic directions of reforming fiscal policy have been identified. It is substantiated that in order to achieve an effective fiscal policy at the macro level it is necessary to create conditions for optimal filling of the state budget and contain inflationary processes. At the meso level it is necessary to ensure the fulfillment of tasks that promote economic growth in the regions and at the micro level ̶ to identify and implement measures to enhance the development of business structures through improvement of the investment climate. It is argued that for this purpose it is important to develop and implement an effective fiscal policy of Ukraine strategy that should include the following smart directions in the field of fiscal policy: improving the combination of fiscal and budgetary spheres in regulation, planning, management with the goal of achieving the maximum results of increasing the welfare of the population; determination of effective communication chains between business centers and the state fiscal service in the course of tax administration, the formation of an objective tax control system. It is pointed that the implementation of the fiscal mechanism combines the fiscal and budgetary mechanisms and includes the mobilization of financial resources from tax payments, as well as their distribution and effective use. It is noted that the instruments of the fiscal mechanism are means for influencing the formation of the optimal amount of financial resources for their further use, in turn, each instrument within the fiscal mechanism has its own functional load. So, expanding the functional boundaries of

  19. National energy policy provides scant power direction. [Canada

    Energy Technology Data Exchange (ETDEWEB)

    1976-05-07

    More federal direction on electric power developments was expected than actually materialized in the national energy policy released recently by Energy, Mines, and Resources. None of the primary objectives was specifically geared to improving the sagging power outlook. The five targets mentioned would have varying positive influences on Canadian power security if achieved, but oil and gas problems stole the spotlight. Failure of a national energy grid to make the top priority list was a disappointment. Observers had been expecting more prominent treatment for grid schemes in light of comments made by energy minister Alastair Gillespie at the recent energy conservation conference in Ottawa. But the strategy paper merely endorses the strengthening of regional interconnections, particularly in eastern Canada, and urges closer coordination among provincial utilities in planning and development. It reveals no new move to spur grid action and only reiterates the federal offer to back 50 percent of interconnection studies and capital costs. The paper does recognize that strengthened regional ties would lead to a form of integrated national system permitting more efficient systems growth, mutual assistance in the event of power failures, and some averaging out of peak and off-peak loads. They would economize on the need for stand-by power and enhance more rational expansion.

  20. Direct effect of nicotine on mesolimbic dopamine release in rat nucleus accumbens shell

    NARCIS (Netherlands)

    Kleijn, J.; Folgering, J. H. A.; van der Hart, M. C. G.; Rollema, H.; Cremers, T. I. F. H.; Westerink, B. H. C.

    2011-01-01

    Nicotine stimulates dopamine (DA) cell firing via a local action at somatodendritic sites in the ventral tegmental area (VTA), increasing DA release in the nucleus accumbens (NAcc). Additionally, nicotine may also modulate DA release via a direct effect in the NAcc. This study examined the

  1. New welfare, new policies: towards preventive worker-directed active labour market policies?

    NARCIS (Netherlands)

    van Berkel, H.H.A.; van der Aa, P.H.J.

    2015-01-01

    Debates about the new welfare, and the new social policies that go (or should go) with it, share an emphasis on risk-prevention strategies and pluralistic risk management. Focusing specifically on the risk of unemployment, this article discusses the case for so-called preventive worker-directed

  2. A Korean perspective on developing a global policy for advance directives.

    Science.gov (United States)

    Kim, Soyoon; Hahm, Ki-Hyun; Park, Hyoung Wook; Kang, Hyun Hee; Sohn, Myongsei

    2010-03-01

    Despite the wide and daunting array of cross-cultural obstacles that the formulation of a global policy on advance directives will clearly pose, the need is equally evident. Specifically, the expansion of medical services driven by medical tourism, just to name one important example, makes this issue urgently relevant. While ensuring consistency across national borders, a global policy will have the additional and perhaps even more important effect of increasing the use of advance directives in clinical settings and enhancing their effectiveness within each country, regardless of where that country's state of the law currently stands. One cross-cultural issue that may represent a major obstacle in formulating, let alone applying, a global policy is whether patient autonomy as the underlying principle for the use of advance directives is a universal norm or a construct of western traditions that must be reconciled with alternative value systems that may place lesser significance on individual choice. A global policy, at a minimum, must emphasize respect for patient autonomy, provision of medical information, limits to the obligations for physicians, and portability. And though the development of a global policy will be no easy task, active engagement in close collaboration with the World Health Organization can make it possible.

  3. Directed technical change and differentiation of climate policy

    International Nuclear Information System (INIS)

    Otto, Vincent M.; Loeschel, Andreas; Reilly, John

    2008-01-01

    This paper studies the cost effectiveness of climate policy if there are technology externalities. For this purpose, we develop a forward looking model that captures empirical links between CO 2 emissions associated with energy use, directed technical change and the economy. We find our most cost effective climate policy to include a combination of R and D subsidies and CO 2 emission constraints, although R and D subsidies raise the shadow value of the CO 2 constraint (i.e. CO 2 price) because of a strong rebound effect from stimulating innovation. Furthermore, we find that cost effectiveness of climate policy improves if it is differentiated between technologies. Even our rudimentary distinction between CO 2 intensive technologies and non-CO 2 intensive technologies lead to this result. Such differentiated climate policy encourages growth in the non-CO 2 intensive sectors and discourages growth in CO 2 intensive sectors by harnessing positive effects of technology externalities on total factor productivity in the former and letting the latter bear relatively more of the abatement burden. This result is robust to whether emission constraints, R and D subsidies or combinations of both are used as climate policy instruments. (author)

  4. Directed technical change and differentiation of climate policy

    NARCIS (Netherlands)

    Otto, V.M.; Löschel, A.; Reilly, J.

    2008-01-01

    This paper studies the cost effectiveness of climate policy if there are technology externalities. For this purpose, we develop a forward looking model that captures empirical links between CO2 emissions associated with energy use, directed technical change and the economy. We find our most cost

  5. New Directions for Hardware-assisted Trusted Computing Policies (Position Paper)

    Science.gov (United States)

    Bratus, Sergey; Locasto, Michael E.; Ramaswamy, Ashwin; Smith, Sean W.

    The basic technological building blocks of the TCG architecture seem to be stabilizing. As a result, we believe that the focus of the Trusted Computing (TC) discipline must naturally shift from the design and implementation of the hardware root of trust (and the subsequent trust chain) to the higher-level application policies. Such policies must build on these primitives to express new sets of security goals. We highlight the relationship between enforcing these types of policies and debugging, since both activities establish the link between expected and actual application behavior. We argue that this new class of policies better fits developers' mental models of expected application behaviors, and we suggest a hardware design direction for enabling the efficient interpretation of such policies.

  6. How effective are directed credit policies in the United States? A literature survey

    OpenAIRE

    Schwarz, Anita M.

    1992-01-01

    Schwarz surveys U.S. experience with directed credit as background for a larger study of the Asian experience. Almost half of net credit lent in the United States annually is directly affected by government policies - half of net credit covering budget deficits, and half falling under various federal credit programs. The main difference between U.S. and Asian credit policy is that U.S. credit policy is oriented more toward equity than toward growth. Different sectors are affected differently ...

  7. Carbon leakage revisited. Unilateral climate policy under directed technical change

    International Nuclear Information System (INIS)

    Maria, Corrado Di; Van derWerf, E.

    2005-01-01

    This paper analyzes the consequences of unilateral climate policy in the presence of directed technical change. We develop a dynamic two-country model in which two otherwise identical countries differ in their environmental policy: one of the countries enforces a (binding) cap on emissions while the other does not. Focusing on carbon leakage, we show how, compared with a 'traditional' endogenous growth model, directed technical change will always lead to lower emissions in the unconstrained country. When clean and dirty goods are good substitutes, it may even be induced to reduce its emissions below the optimum level when both countries are unconstrained, so leakage is negative

  8. fundamental objectives and directives principles of state policy

    African Journals Online (AJOL)

    Mofasony

    and Directive Principles of State policy in the Constitution of the Federal ... The Social Contract theory of the school of jurisprudence opines that the ... privatization process contrary to law and public concerns as expressed by local ... among Nigerians of different ethnic, linguistic, religions or other background and the.

  9. 78 FR 54466 - Federal Open Market Committee; Domestic Policy Directive of July 30-31, 2013

    Science.gov (United States)

    2013-09-04

    ... percent. The Committee directs the Desk to undertake open market operations as necessary to maintain such... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of July 30-31... 271), there is set forth below the domestic policy directive issued by the Federal Open Market...

  10. 78 FR 70945 - Federal Open Market Committee; Domestic Policy Directive of October 29-30, 2013

    Science.gov (United States)

    2013-11-27

    ...\\ percent. The Committee directs the Desk to undertake open market operations as necessary to maintain such... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of October 29-30... 271), there is set forth below the domestic policy directive issued by the Federal Open Market...

  11. 78 FR 13673 - Federal Open Market Committee; Domestic Policy Directive of January 29-30, 2013

    Science.gov (United States)

    2013-02-28

    ... percent. The Committee directs the Desk to undertake open market operations as necessary to maintain such... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of January 29-30... 271), there is set forth below the domestic policy directive issued by the Federal Open Market...

  12. 78 FR 22880 - Federal Open Market Committee; Domestic Policy Directive of March 19-20, 2013

    Science.gov (United States)

    2013-04-17

    ...\\ percent. The Committee directs the Desk to undertake open market operations as necessary to maintain such... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of March 19-20... 271), there is set forth below the domestic policy directive issued by the Federal Open Market...

  13. 78 FR 43883 - Federal Open Market Committee; Domestic Policy Directive of June 18-19, 2013

    Science.gov (United States)

    2013-07-22

    ...\\ percent. The Committee directs the Desk to undertake open market operations as necessary to maintain such... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of June 18-19... 271), there is set forth below the domestic policy directive issued by the Federal Open Market...

  14. Fiscal policy and TFP in the OECD: Measuring direct and indirect effects

    OpenAIRE

    Everaert, Gerdie; Heylen, Freddy; Schoonackers, Ruben

    2014-01-01

    This paper analyzes the direct and indirect effects of fiscal policy on total factor productivity (TFP) in a panel of OECD countries over the period 1970-2012. Our contribution is twofold. First, when estimating the impact of fiscal policy on TFP from a production function approach, we identify the worldwide available level of technology by exploiting the observed strong cross-sectional dependence between countries instead of using ad hoc proxies for technology. Second, next to direct effects...

  15. Implementing Indigenous Education Policy Directives in Ontario Public Schools: Experiences, Challenges and Successful Practices

    Directory of Open Access Journals (Sweden)

    Emily Milne

    2017-08-01

    Full Text Available The Ontario Ministry of Education has declared a commitment to Indigenous student success and has advanced a policy framework that articulates inclusion of Indigenous content in schooling curriculum (Ontario Ministry of Education, 2007. What are the perceptions among educators and parents regarding the implementation of policy directives, and what is seen to encourage or limit meaningful implementation? To answer these questions, this article draws on interviews with 100 Indigenous (mainly Haudenosaunee, Anishinaabe, and Métis and non-Indigenous parents and educators from Ontario Canada. Policy directives are seen to benefit Indigenous and non-Indigenous students. Interviews also reveal challenges to implementing Indigenous curricular policy, such as unawareness and intimidation among non-Indigenous educators regarding how to teach material. Policy implications are considered.

  16. Suggestions of Policy Direction to Improve the Housing Quality in South Korea

    Directory of Open Access Journals (Sweden)

    Miyeon Park

    2016-05-01

    Full Text Available Following the recent global climate changes, many countries, including developed nations, are announcing greenhouse gas (GHG reduction targets and are actively participating in reducing GHG. Therefore, the role of the building sector on reducing GHG is being emphasized, and the establishment of policy structures for both making environmentally friendly capacity compulsory and improving the housing quality is being demanded. South Korea is also developing a policy for improving housing quality, but in order to achieve more competitive growth, this must be preceded by an analysis of current policy status within various countries on improving housing quality. This study aims to suggest direction about policies that will improve the housing quality in South Korea. For this, the policies of major countries were able to categorize and compare according to three major categories (performance, function, and aesthetics, and seven factors (safety, durability, cost and maintenance, response to residents’ needs, habitability, energy saving, and building design regarding housing quality. As a result, from the performance aspect, policy directions were suggested for safe housing, the urban environment, regeneration of quality stock, and the usage of existing stock; from the functional aspect, policies for improving housing quality that responds to the aging population and energy saving housing were suggested; from the aesthetic aspect, housing designs that consider the urban environment were suggested.

  17. Development and release of phenological data products—A case study in compliance with federal open data policy

    Science.gov (United States)

    Rosemartin, Alyssa H.; Langseth, Madison L.; Crimmins, Theresa M.; Weltzin, Jake F.

    2018-01-31

    In Autumn 2015, USA National Phenology Network (USA-NPN) staff implemented new U.S. Geological Survey (USGS) data-management policies intended to ensure that the results of Federally funded research are made available to the public. The effort aimed both to improve USA-NPN data releases and to provide a model for similar programs within the USGS. This report provides an overview of the steps taken to ensure compliance, following the USGS Science Data Lifecycle, and provides lessons learned about the data-release process for USGS program leaders and data managers.

  18. 78 FR 33841 - Federal Open Market Committee; Domestic Policy Directive of April 30-May 1, 2013

    Science.gov (United States)

    2013-06-05

    ... from 0 to \\1/4\\ percent. The Committee directs the Desk to undertake open market operations as... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of April 30-May 1... 271), there is set forth below the domestic policy directive issued by the Federal Open Market...

  19. Innovation policy for directing technical change in the power sector

    International Nuclear Information System (INIS)

    Aalbers, Rob; Shestalova, Victoria; Kocsis, Viktória

    2013-01-01

    This paper discusses policy instruments for redirecting technical change within the electricity sector to mitigate climate change. First, we unravel the mechanism behind directed technical change, explaining why markets may underprovide innovations in expensive renewable technologies in comparison to innovations in energy-efficient fossil-fuel generators. Subsequently, we characterize technical change in electricity generation technologies, stressing the heterogeneity of knowledge spillovers both within and between clean electricity generation technologies. We argue that there exists a rationale for a portfolio approach to innovation in the electricity sector, i.e., optimal innovation policies are neither fully generic nor fully specific; and they need to be adapted, in response to new information learned by the government. The existing innovation literature does not, however, provide a clear-cut answer for designing such a policy. We compare policy instruments and argue that public R and D support to clean technologies, either in the form of subsidies or prizes, seems to be the prime candidate for implementing non-generic innovation policy. - Highlights: • We analyze policies for spurring innovations in renewable electricity technologies. • The analysis unravels why research markets underprovide such innovations. • We conclude that non-generic R and D subsidies and prizes are the most suitable policies

  20. Intersectional policy analysis of self-directed mental health care in Canada.

    Science.gov (United States)

    Cook, Judith A; Morrow, Marina; Battersby, Lupin

    2017-06-01

    Recovery from mental illness is influenced by one's social location along multiple dimensions of identity, such as race, class, gender, age, and ability, and by how these social locations are expressed through structural and institutional barriers. This project was developed using an intersectional policy analysis framework designed to promote equity across identity locations-called the multistrand method-to examine the potential use of self-directed care financing approaches in the Canadian mental health system. A panel of 16 diverse stakeholders came together 4 times at structured 6-hr meetings to examine the evidence for self-directed care and explore its application in the Canadian context. Telephone interviews with evidence panel members were conducted to assess their perceptions of the group process and outcomes. Our analysis revealed ways that intersecting strand locations might differentially influence the degree of choice and recovery experienced by self-directed care participants. Individualized resource allocation, draining financial resources from ethnically specific services, unevenness in acceptance of the recovery orientation, and paucity of service options in different geographical regions were identified as contexts in which self-directed care policies could promote inequity. However, greater peer involvement in the model's implementation, use of indigenous community supports, purchase of material goods by economically disenfranchised persons, and access to services from ethnically diverse clinicians in the private sector were identified as equity-promoting model features. By couching their analysis at the level of unique socially-situated perspectives, the group developed detailed policy recommendations and insights into both the potential and limitations of self-directed care. The knowledge gained from our project can be used to develop uniquely Canadian self-directed care models tailored to promote recovery through empowerment and self

  1. Fundamental Objectives and Directives Principles of State Policy: A ...

    African Journals Online (AJOL)

    Corruption is a term that is eclectic. It is a global phenomenon that has paired itself with both past and present civilizations. Financial corruption is a variant of this obnoxious ill of modern state, Nigeria not being an exception. The provisions of the Fundamental Objectives and Directive Principles of State policy in the ...

  2. FOREIGN DIRECT INVESTMENT: DIAGNOSIS AND PROPOSALS FOR A BRAZILIAN PUBLIC POLICY

    Directory of Open Access Journals (Sweden)

    Milton de Abreu Campanario

    2011-01-01

    Full Text Available The text is the part of public policy of a larger research project on Brazilian Outward ForeignDirect Investment - OFDI. The text analyses the viability to adopt policies to enhance FDI,particularly outward. Based on statistical data and on literature review, the policy agenda framesthe underling questions surrounding the theme. There is not yet a theoretical framework to dealwith emergent countries’ FDI and related policies. There exist strong evidences that capital flowsthrough FDI generate externalities in the following domains: macroeconomics, microeconomicsand foreign relations particularly in areas related to industrial organization and innovation. Thetheoretical proposition is that international capital flows are compatible to monetary stability,commercial openness, investment promotion and industrial innovation policies. A betterpositioning of national enterprises internationally may result in growing partnership within theforeign environment. Brazil has not a set of policies to deal with inward and outward BrazilianFDI flows. These policies do not necessarily jeopardize macroeconomic policy and the relatedmonetary and currency stabilization goals. It contends that FDI stimulus by means of publicpolicies may contribute not just to a better competitiveness and innovation of Brazilianenterprises, but also assure a balanced growing and economic structural change.

  3. National policy measures. Right approach to foreign direct investment flows

    Directory of Open Access Journals (Sweden)

    Cătălin-Emilian HUIDUMAC-PETRESCU

    2013-02-01

    Full Text Available 2011 was a difficult year for all the countries, developed and emerging ones. For overcoming the negative effects of the financial crisis, many economies have established as purpose to adopt new economic policies regarding the foreign direct investment flows (FDI, even to stimulate the flows or to reduce it (protectionism measures. So, there can be identified two categories of national policies: measures for the FDI flows stimulation and measures whose aim was the weighting of FDI developing, through restriction and regulation. In the first category we could include the liberalization measures and promotional and faciletation policies. In this study we evidenced that the fundament of the second category of policies is the belief that the FDI outward lead to job exports, to a raise of unemployment and a weakness of the industrial base.Many reports on FDI flows, here we talk about those made by UNCTAD, show that the regulation and restriction policies are seen as a possible protectionism, especially in the agricultural and extractive industries, where there have been required nationalization processes and divestments. Even more, the economies which adopted this kind of policies have been less interested in investing abroad, the outward of FDI being affected and globally the total outward decreased.

  4. The Initial Purging Policies after the 1965 Incident at Lubang Buaya

    Directory of Open Access Journals (Sweden)

    Yosef Djakababa

    2013-01-01

    Full Text Available After the Lubang Buaya incident on 1 October 1965 in which six top Indonesian Army generals and a lieutenant were killed, the Army began to implement a nationwide purging campaign with the assistance of civilian anti-communist groups. Thousands of PKI members, supporters and pro-Sukarno groups/individuals immediately became the target of this purge. For organisational purposes, several purging policies were released and then strictly enforced. The official purging policies that are highlighted in this paper are a series of initial directives that were released within days of the generals’ executions. They do not explicitly translate into orders to kill, but are more of a guideline to help anti-communist officials classify and contain communists and other PKI followers. This article attempts to show how these initial directives evolved and also discusses competing purge policies from non-military sources. The co-existence and overlapping nature of the various directives indicate that a power struggle existed between the anti-communist group led by General Soeharto and the presidium of the Dwikora Cabinet who were loyal to President Soekarno.

  5. Direct payments as an instrument of the environmental policy

    Directory of Open Access Journals (Sweden)

    Adrian Sadłowski

    2011-01-01

    Full Text Available Agriculture is the area of human activity that is accompanied by the formation of positive and negative external environmental effects. In order to motivate farmers to conduct production activities in a way that reduces the negative impact of these activities on the environment, the so-called principle of cross compliance has been incorporated into the direct support system. This study characterises the area payments as an instrument of the environmental policy and is a review of the European Commission’s different proposals for the reform of direct payments through the prism of environmental functions of this instrument.

  6. New Directions in Education? A Critique of Contemporary Policy Reforms

    Science.gov (United States)

    Skourdoumbis, Andrew

    2016-01-01

    This paper draws on facets of Foucault's theoretical resources to critique current education policy reform from within the Australian State of Victoria, namely the Department of Education and Early Childhood Development's (DEECD) discussion paper "New directions for school leadership and the teaching profession." Implicit in the reform…

  7. Metering Best Practices, A Guide to Achieving Utility Resource Efficiency, Release 2.0

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Greg; Hunt, W. D.; Pugh, Ray; Sandusky, William F.; Koehler, Theresa M.; Boyd, Brian K.

    2011-08-31

    This release is an update and expansion of the information provided in Release 1.0 of the Metering Best Practice Guide that was issued in October 2007. This release, as was the previous release, was developed under the direction of the U.S. Department of Energy's Federal Energy Management Program (FEMP). The mission of FEMP is to facilitate the Federal Government's implementation of sound cost-effective energy management and investment practices to enhance the nation's energy security and environmental stewardship. Each of these activities is directly related to achieving requirements set forth in the Energy Policy Acts of 1992 and 2005, the Energy Independence and Security Act (EISA) of 2007, and the goals that have been established in Executive Orders 13423 and 13514 - and also those practices that are inherent in sound management of Federal financial and personnel resources.

  8. The Effects of Foreign Government Policies on the Location of U.S. Direct Investment Abroad

    Directory of Open Access Journals (Sweden)

    Kee Min

    2001-06-01

    Full Text Available Many argue about which policy and non-policy variables play an important role in influencing foreign direct investment decisions. This article contributes to this debate by considering the effects of foreign government policies on the location of U.S. direct investment abroad. The analysis used pooled cross-section and time series data for 44 countries over three time periods to examine the effects of different types of non-policy and policy variables, including market size, per capita income, country risks, tax rates, investment incentives, and investment regulations. This study found that a policy variable, investment regulation and two non-policy variables, market size and per capita income impact investment decision. A moderately strong effect is found in investment incentive policy, whereas country risks and tax rates turned out not to be strong factors in influencing U.S. investment locations. However, in the case of FDI in developing countries, country risk and tax rates appeared to be more important factors for the location of U.S. FDI than host countries' market size. Strong interaction effects between policy variable and market size are found, while less strong interaction is found between policy variable and per capita income. This study concludes that policy variables are also important factors along with non-policy factors and the determinants of FDI are not independently exerting an influence but jointly affecting U.S. investment locations.

  9. Advancing the Field Elder Abuse: Future Directions and Policy Implications

    Science.gov (United States)

    Dong, XinQi

    2012-01-01

    Elder abuse, sometime called elder mistreatment or elder maltreatment, includes psychological, physical, and sexual abuse, neglect (caregiver neglect and self-neglect), and financial exploitation. Evidence suggests that 1 out of 10 older adult experiences some form of elder abuse, and only 1 of out 25 cases are actually reported to social services agencies. At the same time, elder abuse is associated with significant morbidity and premature mortality. Despite these findings, there is a great paucity in research, practice, and policy dealing with the pervasive issues of elder abuse. Through my experiences as a American Political Sciences Association Congressional Policy Fellow/Health and Aging Policy Fellow working with Administration on Community Living (ACL) (Previously known at Administration on Aging (AoA)) for the last two years, I will describe the major functions of the ACL; and highlight on two major pieces of federal legislation: The Older Americans Act (OAA) and the Elder Justice Act (EJA). Moreover, I will highlight major research gaps and future policy relevant research directions for the field of elder abuse. PMID:23110488

  10. Integrating Financial Aid and Financial Policies: Case Studies from Five States. Changing Direction: Integrating Higher Education Financial Aid and Financing Policies.

    Science.gov (United States)

    Western Interstate Commission for Higher Education, Boulder, CO.

    This report is a collection of five state case studies comprising a major component of the first phase of the project, "Changing Direction: Integrating Higher Education Financial Aid and Financing Policies." The project explored state-level strategies to better align financing and financial aid policies and support more informed decision…

  11. Optimal advanced credit releases in ecosystem service markets.

    Science.gov (United States)

    BenDor, Todd K; Guo, Tianshu; Yates, Andrew J

    2014-03-01

    Ecosystem service markets are popular policy tools for ecosystem protection. Advanced credit releases are an important factor affecting the supply side of ecosystem markets. Under an advanced credit release policy, regulators give ecosystem suppliers a fraction of the total ecosystem credits generated by a restoration project before it is verified that the project actually achieves the required ecological thresholds. In spite of their prominent role in ecosystem markets, there is virtually no regulatory or research literature on the proper design of advanced credit release policies. Using U.S. aquatic ecosystem markets as an example, we develop a principal-agent model of the behavior of regulators and wetland/stream mitigation bankers to determine and explore the optimal degree of advance credit release. The model highlights the tension between regulators' desire to induce market participation, while at the same time ensuring that bankers successfully complete ecological restoration. Our findings suggest several simple guidelines for strengthening advanced credit release policy.

  12. Challenges for decommissioning policies

    International Nuclear Information System (INIS)

    Riotte, H.

    2007-01-01

    In the coming years, OECD member countries will be increasingly faced with the need to make appropriate provisions, in terms of policy, finance and management, for all aspects of decommissioning. Decommissioning requires regulatory approval and oversight, the directions of which are guided by national policy. In several instances, governments have only recently begun to address their approaches to decommissioning policy and regulation in national legislation, and international overviews of such approaches, which may eventually lead to international harmonization, are only now beginning to emerge. In parallel, policy and regulation have been evolving and a broadened competence has developed in relevant regulatory authorities. The challenge lying ahead is to establish a framework that will allow for the growth of nuclear industrial activities in competitive, globalized markets, while maintaining and assuring the safety of decommissioning for the public and for workers. Within this context, institutional arrangements, stakeholder issues, costs and funding, waste management and policies for release from regulatory control, as well as the availability of technologies and skills, need to be reviewed. (author)

  13. The comparison between limited open carpal tunnel release using direct vision and tunneling technique and standard open carpal tunnel release: a randomized controlled trial study.

    Science.gov (United States)

    Suppaphol, Sorasak; Worathanarat, Patarawan; Kawinwongkovit, Viroj; Pittayawutwinit, Preecha

    2012-04-01

    To compare the operative outcome of carpal tunnel release between limited open carpal tunnel release using direct vision and tunneling technique (group A) with standard open carpal tunnel release (group B). Twenty-eight patients were enrolled in the present study. A single blind randomized control trial study was conducted to compare the postoperative results between group A and B. The study parameters were Levine's symptom severity and functional score, grip and pinch strength, and average two-point discrimination. The postoperative results between two groups were comparable with no statistical significance. Only grip strength at three months follow up was significantly greater in group A than in group B. The limited open carpal tunnel release in the present study is effective comparable to the standard open carpal tunnel release. The others advantage of this technique are better cosmesis and improvement in grip strength at the three months postoperative period.

  14. Foreign Direct Investment and Government Policy in Central and Eastern Europe

    DEFF Research Database (Denmark)

    Meyer, Klaus E.; Jensen, Camilla

    2004-01-01

    The 1990s have been a period of extraordinary politics in Central and Eastern Europe (CEE). This chapter discusses how the transition from state to market has created bureaucratic barriers to entry, but also windows of opportunity for foreign direct investment (FDI). The high costs and high...... investment risks associated with FDI in CEE are a reflection the institutional development. Thus, inflows of FDI have been largest in those countries that made most progress in establishing a market-oriented institutional framework. After outlining trends of institutional change and their impact on FDI......, this chapter discusses how aspects of the institutional framework and FDI policy affect diverse types of investment projects. Acquisition and Greenfield investors are concerned with different aspects of government policy: privatization and regulatory policies for acquirers and investment incentives, regional...

  15. A novel co-processed directly compressible release-retarding polymer: In vitro, solid state and in vivo evaluation

    Directory of Open Access Journals (Sweden)

    Prashant Kumar Choudhari

    2018-06-01

    Full Text Available Directly compressible (DC co-processed excipient capable of providing nearly zero order release with improved functionality was developed without any chemical modification by employed various techniques such as physical mixing, high shear mixer granulation and spray drying. Co-processed excipient was developed by using release retarding polymer Eudragit RSPO, separately, in combination with different concentration of hydroxyl propyl methyl cellulose 100 cps (Methocel K100 LV, HPMC, ethyl cellulose (Ethocel N50, EC and hydroxyl propyl cellulose (Klucel EF, HPC. All co-processed excipients were evaluated for their flow properties in terms of angle of repose, bulk density, tapped density, compressibility index and Hausner's ratio. Out of eighteen combinations, the nine co-processed excipients exhibited promising flow properties were found suitable for direct compression and formulated as tablets. Metoprolol succinate, a BCS Class I drug, was selected as a model drug and the formulation was developed employing direct compression approach. The developed tablets were evaluated for physical parameters like uniformity of weight, thickness, hardness, friability and assay. In vitro dissolution study confirms that formulation prepared using co-processed excipient showed sustained drug release. The optimized tablet formulation was characterized by DSC, FTIR and PXRD which confirms the absence of any chemical change during co-processing. The optimized formulation was kept for stability study for six months as per ICH guidelines and found to be stable. In vivo pharmacokinetic study of optimized formulation in rats showed similar pharmacokinetic behaviour as was observed with the marketed brand. Study revealed that co-processed excipient has advantage over polymers with single property and can be utilised for sustained release formulation. Keywords: Co-processed excipient, Metoprolol succinate, Extended-release, Direct compression, Zero-order release

  16. Advancing the field of elder abuse: future directions and policy implications.

    Science.gov (United States)

    Dong, XinQi

    2012-11-01

    Elder abuse, sometimes called elder mistreatment or elder maltreatment, includes psychological, physical, and sexual abuse; neglect (caregiver neglect and self-neglect); and financial exploitation. Evidence suggests that one in 10 older adults experiences some form of elder abuse, but only one in 25 cases is reported to social services agencies. At the same time, elder abuse is associated with significant morbidity and premature mortality. Despite these findings, there is a great paucity in research, practice, and policy addressing the pervasive issues of elder abuse. Through my experiences as a American Political Sciences Association Congressional Policy Fellow and Health and Aging Policy Fellow working with the Administration on Community Living (ACL) (previously known as the Administration on Aging) for the last 2 years, I will describe the major functions of the ACL and highlight two major pieces of federal legislation: The Older Americans Act and the Elder Justice Act. I will also highlight major research gaps and future policy relevant research directions for the field of elder abuse. © 2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society.

  17. Outcomes of Direct Facial-to-Hypoglossal Neurorrhaphy with Parotid Release.

    Science.gov (United States)

    Jacobson, Joel; Rihani, Jordan; Lin, Karen; Miller, Phillip J; Roland, J Thomas

    2011-01-01

    Lesions of the temporal bone and cerebellopontine angle and their management can result in facial nerve paralysis. When the nerve deficit is not amenable to primary end-to-end repair or interpositional grafting, nerve transposition can be used to accomplish the goals of restoring facial tone, symmetry, and voluntary movement. The most widely used nerve transposition is the hypoglossal-facial nerve anastamosis, of which there are several technical variations. Previously we described a technique of single end-to-side anastamosis using intratemporal facial nerve mobilization and parotid release. This study further characterizes the results of this technique with a larger patient cohort and longer-term follow-up. The design of this study is a retrospective chart review and the setting is an academic tertiary care referral center. Twenty-one patients with facial nerve paralysis from proximal nerve injury at the cerebellopontine angle underwent facial-hypoglossal neurorraphy with parotid release. Outcomes were assessed using the Repaired Facial Nerve Recovery Scale, questionnaires, and patient photographs. Of the 21 patients, 18 were successfully reinnervated to a score of a B or C on the recovery scale, which equates to good oral and ocular sphincter closure with minimal mass movement. The mean duration of paralysis between injury and repair was 12.1 months (range 0 to 36 months) with a mean follow-up of 55 months. There were no cases of hemiglossal atrophy, paralysis, or subjective dysfunction. Direct facial-hypoglossal neurorrhaphy with parotid release achieved a functional reinnervation and good clinical outcome in the majority of patients, with minimal lingual morbidity. This technique is a viable option for facial reanimation and should be strongly considered as a surgical option for the paralyzed face.

  18. News/Press Releases

    Data.gov (United States)

    Office of Personnel Management — A press release, news release, media release, press statement is written communication directed at members of the news media for the purpose of announcing programs...

  19. Southern Philippines and the policy of the second front in the global war on terrorism

    OpenAIRE

    Choi, Jihoon P.

    2009-01-01

    Approved for public release, distribution unlimited This thesis analyzes the effects of the United States' policy of the second front in the global war on terrorism (GWOT) on the conflict in the southern Philippines. The policy's reliance on intervention measures that are both "preemptive" and "direct" by military means echoes Mearsheimer's argument that "simply put, great powers are primed for offense." The question may be asked: how effective is the second front policy in terms of resolv...

  20. Effectiveness of a personalized ventilation system in reducing personal exposure against directly released simulated cough droplets

    DEFF Research Database (Denmark)

    Pantelic, J.; Tham, K. W.; Licina, Dusan

    2015-01-01

    manikin at distances between 1 and 4m. Cough droplet concentration was measured with an aerosol spectrometer in the breathing zone of a thermal manikin. Particle image velocimetry was used to characterize the velocity field in the breathing zone. Desktop personalized ventilation substantially reduced......The inhalation intake fraction was used as an indicator to compare effects of desktop personalized ventilation and mixing ventilation on personal exposure to directly released simulated cough droplets. A cough machine was used to simulate cough release from the front, back, and side of a thermal...

  1. An exploration of potential directions for climate change policy in Northern Canada

    International Nuclear Information System (INIS)

    Newton, J.

    2001-01-01

    The challenges facing decision and policy makers for climate change actions in the Canadian North were described. While Northern Canada contributes only a small fraction of the world's greenhouse gas (GHG) emissions, the impacts are already being felt there, and scientists forecast changes in average annual temperatures to be among the highest in the world. Canada is well positioned to take a lead role in addressing climate change in northern regions. This paper examined the policy choices in the North and outlined the policy directions worthy of further consideration and development. The objective of the paper is to provide a catalyst for on-going discussion and deliberation on climate change actions and policy options in Northern Canada. The paper also addressed the global context that influences national framework and local initiatives. Some tentative policy choices were proposed and described within the general context of the global challenge that climate change presents for the design of coherent regional public policy. It was suggested that integration and mitigation measures should not be approached in isolation from other environmental and socio-economic changes, such as pollution abatement and economic and social development. It was emphasized that building on the sound foundation of current policy frameworks in these areas is essential to the integration of climate change initiatives within established and complementary processes. It was concluded that the evolution of policy options for climate change in the North will be driven by a political willingness to take deliberate actions. 13 refs., 2 tabs., 1 fig

  2. Hospital policies on life-sustaining treatments and advance directives in Canada.

    OpenAIRE

    Rasooly, I; Lavery, J V; Urowitz, S; Choudhry, S; Seeman, N; Meslin, E M; Lowy, F H; Singer, P A

    1994-01-01

    OBJECTIVE: To determine the prevalence and content of hospital policies on life-sustaining treatments (cardiopulmonary resuscitation [CPR], mechanical ventilation, dialysis, artificial nutrition and hydration, and antibiotic therapy for life-threatening infections) and advance directives in Canada. DESIGN: Cross-sectional mailed survey. SETTING: Canada. PARTICIPANTS: Chief executive officers or their designates at public general hospitals. MAIN OUTCOME MEASURES: Information regarding the exis...

  3. Future directions for environmental policy

    Energy Technology Data Exchange (ETDEWEB)

    O' Riordan, T

    1984-01-01

    Environmentalism is an elusive concept with many meanings. Its changing character is examined together with an analysis of how it is likely to influence public policy across a broad front. The paper also reviews the major environmental issues which QECD countries are likely to face nationally, regionally and globally over the next twenty years and discusses the type of politics that may emerge within the new environmentalism. The overriding global issue will be the tragic interconnection between poverty and environmental damage in the underdeveloped countries. In the developed but de-industrialising economies of the 'north' greatest attention will be placed on devising means for creating jobs and providing satisfying occupations for people forced out of a job or never in employment. Environmental rehabilitation can create jobs, but it will involve the denial of resources otherwise available to create jobs elsewhere. It will therefore be necessary to consider the 'next job effectiveness' of environmental policies. Another policy area that requires new thinking is the management of environmental hazards, notably how to dispose of toxic wastes in a manner acceptable to a majority of people. Finally serious efforts will have to be made, not only to infuse environmental principles within all policy arenas, but also to ensure that departmental responsibilities and budgets are properly linked. The principle that those who exploit environmental resources should subsidise those who use environmental resources frugally and benignly by means of transfer taxes and payments should also become established. (orig.).

  4. [Nursing performance in the policy transfer of directly observed treatment of tuberculosis].

    Science.gov (United States)

    Souza, Káren Mendes Jorge de; Sá, Lenilde Duarte de; Silva, Laís Mara Caetano da; Palha, Pedro Fredemir

    2014-10-01

    Analyzing the policy transfer of directly observed treatment of tuberculosis from the perspective of nursing. This is a descriptive study with qualitative approach, which had 10 nurses of the Family Health Strategy in São Paulo as subjects. The interviews were carried out between May and June 2013, and were adopted the technique of thematic content analysis and the referential of policy transfer. On the signification of this treatment, are related the senses of disciplinary monitoring, the bond and approximation to the context of patients' lives. Operationally, nurses, community health agents and nursing technicians stand out as agents of implementation of this policy, developing multiple actions of user embracement. The nurse is evidenced as an educator in health, leader in the family health team, and capable of creating emotional bond with users. It was found that the innovations proposed in the treatment are incipient in the daily work of nurses.

  5. Country policy profile - Romania. April 2015

    International Nuclear Information System (INIS)

    2015-04-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Romania is 24%, whereas in 2012 it reached 21,3%. The Romanian renewable electricity promotion relies primarily on a quota system. Grid operators are obliged to develop their grids on the request of a plant operator, if the connection of a plant to the grid requires so. Romania has certain policies pertaining to renewable energy like training programmes for RES installers and on enhancing the development of RES-H infrastructure. This report monitors the policy changes after the release of the 2013 Progress Report for Romania and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  6. Country policy profile - Romania. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Romania is 24%, whereas in 2012 it reached 21,3%. The Romanian renewable electricity promotion relies primarily on a quota system. Grid operators are obliged to develop their grids on the request of a plant operator, if the connection of a plant to the grid requires so. Romania has certain policies pertaining to renewable energy like training programmes for RES installers and on enhancing the development of RES-H infrastructure. This report monitors the policy changes after the release of the 2013 Progress Report for Romania and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  7. Direct and indirect effects of paliperidone extended-release tablets on negative symptoms of schizophrenia

    OpenAIRE

    Bossie, Cynthia

    2008-01-01

    Ibrahim Turkoz, Cynthia A Bossie, Bryan Dirks, Carla M CanusoOrtho-McNeil Janssen Scientific Affairs, LLC, Titusville, NJ, USAAbstract: Direct and indirect effects of the new psychotropic paliperidone extended-release (paliperidone ER) tablets on negative symptom improvement in schizophrenia were investigated using path analysis. A post hoc analysis of pooled data from three 6-week, double-blind, placebo-controlled studies of paliperidone ER in patients experiencing acute exacerbation was con...

  8. Foreign direct investment and policy framework: New Granger causality evidence from African countries

    Directory of Open Access Journals (Sweden)

    Rafiu Adewale Aregbeshola

    2014-11-01

    Full Text Available The strategic importance of foreign direct investment in the contemporary economies has been tremendous.While various countries (developed and developing economies have benefitted from the direct and spillovereffects of FDI, which range from improved technology and knowledge diffusion through to individual andcorporate capability enhancement, FDI outflow remains largely channelled to the developed countries, andthe rapidly developing countries in Asia and South America. Evidence suggests that the developmentenhancingeffects of FDI are felt more highly in the developing economies, such as economies in Africa.However, FDI inflow to the developing economies has been very low. Using data generated from the AfricanDevelopment Indicators (ADI between 1980 and 2008 in econometric estimations, this paper finds thatgovernment policies (especially fiscal and monetary policies play significant roles in facilitating FDI inflow tothe African countries studied. The study thereby suggests an improved regulatory framework to make Africamore attractive to inflow of FDI.

  9. Myanmar’s China Policy since 2011: Determinants and Directions

    Directory of Open Access Journals (Sweden)

    Maung Aung Myoe

    2015-01-01

    Full Text Available This paper argues that a key factor in Myanmar’s new approach towards China since 2011 has been the Myanmar government’s foreign policy goal to reintegrate itself into the international community. The success of this approach is dependent on Myanmar’s rapprochement with the United States, which requires both domestic political reforms and a foreign policy realignment – a need to reduce Myanmar’s dependence on China, particularly in the context of US–China strategic competition in the Indo-Pacific region. In the context of China–Myanmar relations, the factors that have influenced Myanmar’s China policy since 2011 are growing anti-China sentiment in Myanmar, growing concern over China’s interference in Myanmar affairs, and the rapprochement with the United States. Myanmar’s China policy shift, in terms of direction, is by no means to seek to be independent of China, but rather for there to be an increased interdependence between the two countries.

  10. Nursing performance in the policy transfer of directly observed treatment of tuberculosis

    Directory of Open Access Journals (Sweden)

    Káren Mendes Jorge de Souza

    2014-10-01

    Full Text Available Objective Analyzing the policy transfer of directly observed treatment of tuberculosis from the perspective of nursing. Method This is a descriptive study with qualitative approach, which had 10 nurses of the Family Health Strategy in São Paulo as subjects. The interviews were carried out between May and June 2013, and were adopted the technique of thematic content analysis and the referential of policy transfer. Results On the signification of this treatment, are related the senses of disciplinary monitoring, the bond and approximation to the context of patients’ lives. Operationally, nurses, community health agents and nursing technicians stand out as agents of implementation of this policy, developing multiple actions of user embracement. The nurse is evidenced as an educator in health, leader in the family health team, and capable of creating emotional bond with users. Conclusion It was found that the innovations proposed in the treatment are incipient in the daily work of nurses.

  11. Transformation Directions of the Financial Policy in the Process of Stabilisation of the Ukrainian Economy

    Directory of Open Access Journals (Sweden)

    Petrushevska Viktoriya V.

    2013-11-01

    Full Text Available The goal of the article is consideration of theoretical provisions with respect to the state financial policy. The article considers the role of the financial policy in ensuring stabilisation of the Ukrainian financial system. It presents conceptual provisions regarding main goals, mechanisms and instruments of the stabilisation financial policy of the state. It develops economic indicators of its efficiency. The use of indicators of economic efficiency of the stabilisation financial policy by the bodies of state authority in their practical activity would provide the society with a possibility to assess expediency of measures of this policy increasing its efficiency and decreasing criticism at the government. A necessary direction of achievement of effectiveness and efficiency of the stabilisation financial policy is taking into consideration interests of all social groups (population, entrepreneurs, financial institutes and companies, etc. by the bodies of state authority in the process of its development and realisation.

  12. New directions in stabilisation policies

    Directory of Open Access Journals (Sweden)

    Ralf Fendel

    2004-12-01

    Full Text Available Recently, a new class of macroeconomic business cycle models has emerged. Stochastic dynamic general equilibrium models with rational expectations originally employed by RBC researchers are combined with nominal rigidities and imperfect competition traditionally highlighted by New Keynesian economists. This class of models leads to a new paradigm in business cycle theory and stabilization policies. The paper presents the main characteristics and implications of the new class of models in a predominantly non-technical way. In order to highlight the progress connected with the new class of models, it puts them into the context of former debates on stabilization policy, such as the Phillips curve dispute.

  13. Spatial Policy оf Exporting Direct Investments: Features оf China

    Directory of Open Access Journals (Sweden)

    Alina Nikolaevna Novopashina

    2014-03-01

    Full Text Available In recent years, China has shown rapid growth in volumes of foreign direct investment (FDI, which is the consequence of implementing policy. However, the structure of FDI does not correspond to the government-supported areas. Existing theoretical and empirical studies don’t reveal the causes of China’s FDI. Results of the regression analysis (based on panel data for 2003-2010 prove that the most attractive for Chinese investors were countries with following features: 1 rich in mineral resources, 2 possessing advanced technologies, 3 higher than in China income levels, 4 geographic proximity to China and 5 foreign trade openness. Furthermore, features of the current institutional environment in China affect the directions of foreign direct investment. Investors from PRC direct FDI in developing countries which have low quality of institutions as well as China. Investing in these countries is primarily aimed at getting access to their mineral resources and consumer markets. As for investing in developed countries, the reason is acquisition of advanced technologies which they possess. Directions of FDI in these countries, on the contrary, are determined by the high quality of institutions

  14. Label, nudge or tax? A review of health policies for risky behaviours.

    Science.gov (United States)

    Galizzi, Matteo M

    2012-02-17

    This work proposes a critical, non systematic, review of the three main lines of health policy interventions to deal with risky behaviours, such as over-eating, smoking, sedentary lives, and excess alcohol drinking, namely: i) the release of information on health risks and consequences; ii) the use of incentives; and iii) direct policy intervention in markets, through regulation and taxation. First, the health and economic impact of the risky behaviours epidemics are briefly described. Then a critical review follows on the evidence existing on the effectiveness of each type of intervention. The review will also highlight the public health approach staying beyond each type of policy on risky behaviours and critically consider them within the context of more general health and social policy interventions.

  15. The challenges and directions for nuclear energy policy in Japan. Japan's nuclear energy national plan

    International Nuclear Information System (INIS)

    Yanase, Tadao

    2007-01-01

    According to the 'framework for nuclear energy policy' (October, 2005 adopted by cabinet), basic goals of nuclear policy are (1) for nuclear energy to continue to meet more than around 30-40% of electricity supply, and also (2) to further promote a fuel cycle steadily aiming at commercial introduction of a fast breeder by 2050. In order to realize an aim of this framework for nuclear energy policy', the nuclear energy subcommittee of the METI advisory committee deliberated concrete actions and the subcommittee recommendations were drawn up as 'Japan's nuclear energy national plan' in August, 2006 and incorporated as main part of the revised 'basic plan on energy' adopted by the cabinet in March 2007. Backgrounds and directions of future actions for nuclear energy policy were described. (T. Tanaka)

  16. Investigators find hundreds of intentional nuclear releases

    International Nuclear Information System (INIS)

    Lobsenz, G.

    1994-01-01

    Investigators with the federal Advisory Committee on Human Radiation Experiments have said that the category of intentional releases is now known to be larger, in variety and quantity, than the 13 releases identified prior to the committee's formation in January 1994 by President Clinton. The committee is now aware of hundreds of additional intentional releases. In addition to the intentional releases, the committee said it had compiled documents on 400 biomedical experiments involving radiation prior to 1975, and had at least fragmentary evidence of more than 1,000 more. The committee also discovered a top secret 1953 Defense Department policy statement on human experimentation that was based on the World War II-era Nuremberg Code. The committee said it was looking into how or whether the policy was implemented. The committee is expected to issue a final report, including recommendations on possible compensation for victims by April 1995

  17. Direct encapsulation of water-soluble drug into silica microcapsules for sustained release applications

    International Nuclear Information System (INIS)

    Wang Jiexin; Wang Zhihui; Chen Jianfeng; Yun, Jimmy

    2008-01-01

    Direct encapsulation of water-soluble drug into silica microcapsules was facilely achieved by a sol-gel process of tetraethoxysilane (TEOS) in W/O emulsion with hydrochloric acid (HCl) aqueous solution containing Tween 80 and drug as well as cyclohexane solution containing Span 80. Two water-soluble drugs of gentamicin sulphate (GS) and salbutamol sulphate (SS) were chosen as model drugs. The characterization of drug encapsulated silica microcapsules by scanning electronic microscopy (SEM), FTIR, thermogravimetry (TG) and N 2 adsorption-desorption analyses indicated that drug was successfully entrapped into silica microcapsules. The as-prepared silica microcapsules were uniform spherical particles with hollow structure, good dispersion and a size of 5-10 μm, and had a specific surface area of about 306 m 2 /g. UV-vis and thermogravimetry (TG) analyses were performed to determine the amount of drug encapsulated in the microcapsules. The BJH pore size distribution (PSD) of silica microcapsules before and after removing drug was examined. In vitro release behavior of drug in simulated body fluid (SBF) revealed that such system exhibited excellent sustained release properties

  18. 76 FR 21894 - Federal Open Market Committee; Domestic Policy Directive of March 15, 2011

    Science.gov (United States)

    2011-04-19

    .... The Federal Open Market Committee seeks monetary and financial conditions that will foster price... Market Account Manager and the Secretary will keep the Committee informed of ongoing developments... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of March 15, 2011...

  19. 76 FR 1616 - Federal Open Market Committee; Domestic Policy Directive of December 14, 2010

    Science.gov (United States)

    2011-01-11

    ... Report. The Federal Open Market Committee seeks monetary and financial conditions that will foster price... Market Account Manager and the Secretary will keep the Committee informed of ongoing developments... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of December 14...

  20. Prediction and Validation of Heat Release Direct Injection Diesel Engine Using Multi-Zone Model

    Science.gov (United States)

    Anang Nugroho, Bagus; Sugiarto, Bambang; Prawoto; Shalahuddin, Lukman

    2014-04-01

    The objective of this study is to develop simulation model which capable to predict heat release of diesel combustion accurately in efficient computation time. A multi-zone packet model has been applied to solve the combustion phenomena inside diesel cylinder. The model formulations are presented first and then the numerical results are validated on a single cylinder direct injection diesel engine at various engine speed and timing injections. The model were found to be promising to fulfill the objective above.

  1. TOURISM POLICY IN ROMANIA: A NECESSARY CHANGE OF DIRECTION

    Directory of Open Access Journals (Sweden)

    Vasile DINU

    2009-06-01

    Full Text Available In modern economies services are dominant. As the role of services is increasing, the difference between goods and services is vanishing, but most of our economics and business knowledge is developed from a manufacturing perspective which is no more satisfactory in the new service economy conditions. One important aspect is that the ability of a country to participate effectively to the growing international trade in services depends more and more on its attractiveness as a visitors' destination. Although there is a well developed understanding of the role of tourism to the general economic and social development, it is less understood the effect of economic and social living conditions as visitor attractiveness factors.Reviewing recent studies, assessments and reports regarding the travel & tourism economy of Romania, authors found out that achieving the economic potential of tourism faces serious challenges due, primarily, to the discrepancy between the conditions visitors are increasingly looking for and the conditions provided by Romanian destinations. In order to accept the challenges with chances of success the tourism policy making should radically change direction. The authors identify three main priorities: focus on general development, put policy in the service of visitors first, improve communication and branding.

  2. Leaders' mental health at work: Empirical, methodological, and policy directions.

    Science.gov (United States)

    Barling, Julian; Cloutier, Anika

    2017-07-01

    While employees' mental health is the focus of considerable attention from researchers, the public, and policymakers, leaders' mental health has almost escaped attention. We start by considering several reasons for this, followed by discussions of the effects of leaders' mental health on their own leadership behaviors, the emotional toll of high-quality leadership, and interventions to enhance leaders' mental health. We offer 8 possible directions for future research on leaders' mental health. Finally, we discuss methodological obstacles encountered when investigating leaders' mental health, and policy dilemmas raised by leaders' mental health. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  3. The Direct and Indirect Effects of Paliperidone Extended-release on Depressive Symptoms in Schizoaffective Disorder: A Path Analysis.

    Science.gov (United States)

    Turkoz, Ibrahim; Fu, Dong-Jing; Bossie, Cynthia A; Alphs, Larry

    2015-01-01

    This analysis evaluates improvement in symptoms of depression in patients with schizoaffective disorder administered oral paliperidone extended-release by accounting for the magnitude of direct and indirect (changes in negative and positive symptoms and worsening of extrapyramidal symptoms) treatment effects on depressive symptoms. Data for this post hoc analysis were drawn from two six-week, randomized, placebo-controlled studies of paliperidone extended-release versus placebo in adult subjects with schizoaffective disorder (N=614; NCT00412373, NCT00397033). Subjects with baseline 17-item Hamilton Rating Scale for Depression scores of 16 or greater were included. Structural equation models (path analyses) were used to separate total effects into direct and indirect effects on depressive symptoms. Change from baseline in 17-item Hamilton Rating Scale for Depression score at the Week 6 end point was the dependent variable; changes in Positive and Negative Syndrome Scale positive and negative factors and Simpson-Angus Scale (to evaluate extrapyramidal symptoms) scores were independent variables. At baseline, 332 of 614 (54.1%) subjects had a 17-item Hamilton Rating Scale for Depression score of 16 or greater. Path analysis determined that up to 26.4 percent of the paliperidone extended-release versus placebo effect on depressive symptoms may be attributed to a direct treatment effect, and 45.8 percent and 28.4 percent were mediated indirectly through improvements on positive and negative symptoms, respectively. No effects were identified as mediated through extrapyramidal symptoms changes (-0.7%). RESULTS of this analysis suggest that paliperidone's effect on depressive symptoms in subjects with schizoaffective disorder participating in two six-week, randomized, placebo-controlled studies is mediated through indirect effects (e.g., positive and negative symptom changes) and a direct treatment effect.

  4. Policy Directions Addressing the Public Health Impact of Climate Change in South Korea: The Climate-change Health Adaptation and Mitigation Program.

    Science.gov (United States)

    Shin, Yong Seung; Ha, Jongsik

    2012-01-01

    Climate change, caused by global warming, is increasingly recognized as a major threat to mankind's survival. Climate change concurrently has both direct and modifying influences on environmental, social, and public health systems undermining human health as a whole. Environmental health policy-makers need to make use of political and technological alternatives to address these ramifying effects. The objective of this paper is to review public health policy in Korea, as well as internationally, particularly as it relates to climate change health adaptation and mitigation programs (such as C-CHAMP of Korea), in order to assess and elicit directions for a robust environmental health policy that is adaptive to the health impacts of climate change. In Korea, comprehensive measures to prevent or mitigate overall health effects are limited, and the diffusion of responsibility among various government departments makes consistency in policy execution very difficult. This paper proposes integration, synergy, and utilization as the three core principles of policy direction for the assessment and adaptation to the health impacts of climate change. For specific action plans, we suggest policy making based on scientifically integrated health impact assessments and the prioritization of environmental factors in climate change; the development of practical and technological tools that support policy decisions by making their political implementation more efficient; and customized policy development that deals with the vulnerability of local communities.

  5. Policy Directions Addressing the Public Health Impact of Climate Change in South Korea: The Climate-change Health Adaptation and Mitigation Program

    Science.gov (United States)

    Shin, Yong Seung

    2012-01-01

    Climate change, caused by global warming, is increasingly recognized as a major threat to mankind's survival. Climate change concurrently has both direct and modifying influences on environmental, social, and public health systems undermining human health as a whole. Environmental health policy-makers need to make use of political and technological alternatives to address these ramifying effects. The objective of this paper is to review public health policy in Korea, as well as internationally, particularly as it relates to climate change health adaptation and mitigation programs (such as C-CHAMP of Korea), in order to assess and elicit directions for a robust environmental health policy that is adaptive to the health impacts of climate change. In Korea, comprehensive measures to prevent or mitigate overall health effects are limited, and the diffusion of responsibility among various government departments makes consistency in policy execution very difficult. This paper proposes integration, synergy, and utilization as the three core principles of policy direction for the assessment and adaptation to the health impacts of climate change. For specific action plans, we suggest policy making based on scientifically integrated health impact assessments and the prioritization of environmental factors in climate change; the development of practical and technological tools that support policy decisions by making their political implementation more efficient; and customized policy development that deals with the vulnerability of local communities. PMID:23256088

  6. Foreign direct investment and liberalization policies in Pakistan: An empirical analysis

    Directory of Open Access Journals (Sweden)

    Rana Ejaz Ali Khan

    2014-12-01

    Full Text Available To enhance the inflow of foreign direct investment (FDI and ultimately to increase the economic growth, the countries have implemented a variety of financial and trade liberalization policies in the last three decades. Pakistan also initiated such type of policies. This study makes an analysis of the impact of liberalization (financial and trade in Pakistan, on the inflow of FDI using the time series data of 1971–2009. The DF-GLS test is used to determine the level of integration, and autoregressive distributed lag model to examine the long-run relationship. The results indicate that liberalization indicators, like financial liberalization index and trade openness along with real interest rate, negatively affect the inflow of FDI in Pakistan. Tax revenue of product also negatively affects the FDI. On the other hand, the gross fixed capital formation, infrastructure, and inflation positively influence the FDI in Pakistan. The market size (proxied by real gross domestic product has shown insignificant effect on FDI.

  7. Label, nudge or tax? A review of health policies for risky behaviours

    Directory of Open Access Journals (Sweden)

    Matteo M. Galizzi

    2012-02-01

    Full Text Available This work proposes a critical, non systematic, review of the three main lines of health policy interventions to deal with risky behaviours, such as over-eating, smoking, sedentary lives, and excess alcohol drinking, namely: i the release of information on health risks and consequences; ii the use of financial incentives; and iii direct policy intervention in markets, through regulation and taxation. First, the health and economic impact of the risky behaviours epidemics are briefly described. Then a critical review follows on the evidence existing on the effectiveness of each type of intervention. The review will also highlight the public health approach staying beyond each type of policy on risky behaviours and critically consider them within the context of more general health and social policy interventions.

  8. Direct-to-consumer genetic testing: perceptions, problems, and policy responses.

    Science.gov (United States)

    Caulfield, Timothy; McGuire, Amy L

    2012-01-01

    Direct-to-consumer (DTC) genetic testing has attracted a great amount of attention from policy makers, the scientific community, professional groups, and the media. Although it is unclear what the public demand is for these services, there does appear to be public interest in personal genetic risk information. As a result, many commentators have raised a variety of social, ethical, and regulatory issues associated with this emerging industry, including privacy issues, ensuring that DTC companies provide accurate information about the risks and limitations of their services, the possible adverse impact of DTC genetic testing on healthcare systems, and concern about how individuals may interpret and react to genetic risk information.

  9. Effectiveness of a personalized ventilation system in reducing personal exposure against directly released simulated cough droplets.

    Science.gov (United States)

    Pantelic, J; Tham, K W; Licina, D

    2015-12-01

    The inhalation intake fraction was used as an indicator to compare effects of desktop personalized ventilation and mixing ventilation on personal exposure to directly released simulated cough droplets. A cough machine was used to simulate cough release from the front, back, and side of a thermal manikin at distances between 1 and 4 m. Cough droplet concentration was measured with an aerosol spectrometer in the breathing zone of a thermal manikin. Particle image velocimetry was used to characterize the velocity field in the breathing zone. Desktop personalized ventilation substantially reduced the inhalation intake fraction compared to mixing ventilation for all investigated distances and orientations of the cough release. The results point out that the orientation between the cough source and the breathing zone of the exposed occupant is an important factor that substantially influences exposure. Exposure to cough droplets was reduced with increasing distance between cough source and exposed occupant. The results from this study show that an advanced air distribution system such as personalized ventilation reduces exposure to cough-released droplets better than commonly applied overhead mixing ventilation. This work can inform HVAC engineers about different aspects of air distribution systems’ performance and can serve as an aid in making critical design decisions. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. 76 FR 10364 - Federal Open Market Committee; Domestic Policy Directive of January 25-26, 2011

    Science.gov (United States)

    2011-02-24

    ... Report. The Federal Open Market Committee seeks monetary and financial conditions that will foster price... Market Account Manager and the Secretary will keep the Committee informed of ongoing developments... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of January 25-26...

  11. 76 FR 37114 - Federal Open Market Committee; Domestic Policy Directive of April 26-27, 2011

    Science.gov (United States)

    2011-06-24

    ... Report. The Federal Open Market Committee seeks monetary and financial conditions that will foster price... Market Account Manager and the Secretary will keep the Committee informed of ongoing developments... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of April 26-27...

  12. A study on the long-term nuclear policy direction responding the changes of international and domestic nuclear situation

    International Nuclear Information System (INIS)

    Kim, Hyun Jun; Yang, M. H.; Lee, B. O.; Ham, C. H.; Chung, W. S.; Lee, T. J.; Yun, S. W.; Ko, H. S.; Nha, K. H.

    1998-06-01

    The long-term nuclear policy directions are proposed with three aspects of nuclear technology development policy, nuclear regulatory policy, and tasks required for promoting pro-nuclear movement. Several nuclear technology areas, such as technology for the improvement of nuclear economics, safety enhancement technology, radwaste, treatment/disposal technology, fuel cycle technology, and proliferation-resistant nuclear technology, fuel recycle technology, and proliferation-resistant nuclear technology, appear very important in the future nuclear technology development policy. Nuclear regulation policy should be established with balancing between public safety and expansion of nuclear industry. Objective of nuclear regulation should be recognized not to collapse a nuclear industry, and the worth of nuclear regulatory regime may be also meaningful if nuclear industry can be well developed. It should be necessary to make a proper atmosphere that can resolve revealed or potential problems and issues against the harmonious implementation of nuclear policy. For the purpose, nuclear policy should contain certain policies to promote a nuclear development, such as social policy, international cooperation strategy, and national resource allocation policy. (author). 20 refs., 8 tabs., 5 figs

  13. Heat release effects on mixing scales of non-premixed turbulent wall-jets: A direct numerical simulation study

    International Nuclear Information System (INIS)

    Pouransari, Zeinab; Vervisch, Luc; Johansson, Arne V.

    2013-01-01

    Highlights: ► A non-premixed turbulent flame close to a solid surface is studied using DNS. ► Heat release effects delay transition and enlarge fluctuation of density and pressure. ► The fine-scale structures damped and surface wrinkling diminished due to heat-release. ► Using semilocal scaling improves the collapse of turbulence statistic in inner region. ► There are regions of the flame where considerable (up to 10%) premixed burning occurs. -- Abstract: The present study concerns the role of heat release effects on characteristics mixing scales of turbulence in reacting wall-jet flows. Direct numerical simulations of exothermic reacting turbulent wall-jets are performed and compared to the isothermal reacting case. An evaluation of the heat-release effects on the structure of turbulence is given by examining the mixture fraction surface characteristics, diagnosing vortices and exploring the dissipation rate of the fuel and passive scalar concentrations, and moreover by illustration of probability density functions of reacting species and scatter plots of the local temperature against the mixture fraction. Primarily, heat release effects delay the transition, enlarge the fluctuation intensities of density and pressure and also enhance the fluctuation level of the species concentrations. However, it has a damping effect on all velocity fluctuation intensities and the Reynolds shear stress. A key result is that the fine-scale structures of turbulence are damped, the surface wrinkling is diminished and the vortices become larger due to heat-release effects. Taking into account the varying density by using semi-local scaling improves the collapse of the turbulence statistics in the inner region, but does not eliminate heat release induced differences in the outer region. Examining the two-dimensional premultiplied spanwise spectra of the streamwise velocity fluctuations indicates a shifting in the positions of the outer peaks, associated with large

  14. 78 FR 2996 - Federal Open Market Committee; Domestic Policy Directive of December 11-12, 2012

    Science.gov (United States)

    2013-01-15

    ...'s Annual Report. The Federal Open Market Committee seeks monetary and financial conditions that will... Open Market Account Manager and the Secretary will keep the Committee informed of ongoing developments... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of December 11-12...

  15. 76 FR 43687 - Federal Open Market Committee; Domestic Policy Directive of June 21-22, 2011

    Science.gov (United States)

    2011-07-21

    ... Report. The Federal Open Market Committee seeks monetary and financial conditions that will foster price... Open Market Account Manager and the Secretary will keep the Committee informed of ongoing developments... FEDERAL RESERVE SYSTEM Federal Open Market Committee; Domestic Policy Directive of June 21-22...

  16. Alberta's transmission development policy : review and recommendations

    International Nuclear Information System (INIS)

    Stubbings, R.V.

    2004-01-01

    Alberta's Department of Energy (ADOE) released a policy paper in November 2003 regarding power transmission development for the province. The transmission development policy (TDP) is intended to promote economic growth in Alberta while ensuring consumers with reliable, reasonably priced electricity. This presentation reviewed the main features of the policy and then focused on the allocation of costs to generation customers. The author argued that the proposed changes would result in a sub-optimal development of generation and higher total electricity bills for consumers. He argued that the policy will spare generation customers of any obligation to pay wire-related costs other than local interconnection costs. This would weaken a long-standing ADOE policy which requires generators to pay costs that depend on their location on the transmission system. With the new proposal, generators would not be responsible for ancillary service costs even when they provide direct benefits, and they would pay for system losses on a zonal basis. The author recommended that location charges should be large enough to influence the siting decisions of generators. He also recommended that generators should pay their fare share of transmission use-of-system charges, including ancillary services that provide benefits to generators in the form of a stable, reliable transmission system. 2 tabs., 2 figs

  17. Are Chinese Green Transport Policies Effective? A New Perspective from Direct Pollution Rebound Effect, and Empirical Evidence From the Road Transport Sector

    Directory of Open Access Journals (Sweden)

    Lu-Yi Qiu

    2017-03-01

    Full Text Available Air pollution has become a serious challenge in China. Emissions from motor vehicles have been found to be one main sources of air pollution. Although the Chinese government has undertaken numerous green policies to mitigate harmful emissions from road transport sector, it is still uncertain for both policy makers and researchers to know whether the policies are effective in the short and long terms. We propose a new concept of “pollution rebound effect” (PRE to estimate the effectiveness of green traffic policies. We estimate direct air PRE as a measure of the effectiveness of the policies of reducing air pollution from the transport sector based on time-series data from the period 1986–2014. We find that the short-term direct air PRE is −0.4105, and the corresponding long-run PRE is −0.246. The negative results indicate that the direct air PRE does not exist in the road passenger transport sector in China, both in the short term and in the long term during the period 1986–2014. This implies that the Chinese green transport policies are effective in terms of harmful emissions reduction in the transport sector. This research, to the best of our knowledge, is the first attempt to quantify the effectiveness of the green transport policies in the transitional period that China is currently undergoing.

  18. New directions in Mexican environmental policy

    Science.gov (United States)

    Mumme, Stephen P.; Sanchez, Roberto A.

    1992-07-01

    Since taking office 1 December 1988, Mexico's incumbent president, Carlos Salinas de Gortari, has introduced important innovations in environmental policy that distinguish his administration from those of his predecessors. Greater administrative continuity, improved regulatory capacity achieved through statutory change, focused priorities centering on pollution abatement in Mexico City, and an aggressive search for external financing for pollution control are hallmarks of Salinas' approach. The success of these environmental reforms depends heavily on economic recovery, however, and environmental policy still suffers from underfunding, bureaucratic fragmentation, and heavy reliance on voluntarist enforcement mechanisms. Recently, U.S. congressional debate on a proposed free trade agreement with Mexico has been a factor in spurring the Salinas government to take new antipollution and conservation measures. Mexico's growing environmental movement is also an important force behind the government's new responsiveness in environmental matters. The Salinas administration recognizes the issue's political salience and has sought to defuse environmental criticism using a large arsenal of resources at its disposal. Salinas' environmental policy strategy may thus be characterized as both proactive and reactive in nature. While the reforms are evidence that Mexico is beginning to take environmental matters more seriously, economic recovery and sustained environmental activism remain vital to further progress.

  19. An Analysis of U.S. Foreign Direct Investment Policy and Economic Development. A.I.D. Discussion Paper No. 36.

    Science.gov (United States)

    Bergsten, C. Fred; De Castro, Bruce

    The purpose of the paper is to analyze U.S. policies toward financial investment in developing nations. The paper is presented in two sections. In section I, the controversial effects of direct foreign investment on development are discussed. Case studies of investment policies toward India, the Philippines, Ghana, Guatemala, and Argentina are…

  20. Country policy profile - Hungary. April 2015

    International Nuclear Information System (INIS)

    2015-04-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Hungary is 13%, whereas in 2012 it reached 9,8%. Hungarian renewable electricity meets the support in shape of feed-in tariffs. In the aspect of transport the main means of support for the energy from renewable sources is a quota system. The connection of renewable energy plants to the grid will be ranked as a priority. The costs for the connection of renewable energy plants to and the expansion of the grid are borne either by the plant operator or by the grid operator, depending on certain criteria. There are a number of policies intending to promote the development, installation and use of RES installations. However, some policies are currently not available due to exhausted funds of the related subsidy programs. This report monitors the policy changes after the release of the 2013 Progress Report for Hungary and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  1. Country policy profile - Hungary. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Hungary is 13%, whereas in 2012 it reached 9,8%. Hungarian renewable electricity meets the support in shape of feed-in tariffs. In the aspect of transport the main means of support for the energy from renewable sources is a quota system. The connection of renewable energy plants to the grid will be ranked as a priority. The costs for the connection of renewable energy plants to and the expansion of the grid are borne either by the plant operator or by the grid operator, depending on certain criteria. There are a number of policies intending to promote the development, installation and use of RES installations. However, some policies are currently not available due to exhausted funds of the related subsidy programs. This report monitors the policy changes after the release of the 2013 Progress Report for Hungary and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  2. Country policy profile - Portugal. October 2014

    International Nuclear Information System (INIS)

    2014-10-01

    In Portugal, electricity from renewable sources is mainly promoted through a feed-in tariff (FiT). The support regime for electricity generated from renewable energy sources (except large hydropower plants) is still in place for existing installations and for micro and mini generation units. Support to new installations can be provided through specific power granting tenders. There is currently no direct support mechanism for RES-H. In the transport sector, the main incentives are a bio-fuel quota system and a tax exemption to small producers (PPDs). The Portuguese progress report was released by the EC in June 2014 and no further policy changes have been documented since then

  3. Policies for patient access to clinical data via PHRs: current state and recommendations.

    Science.gov (United States)

    Collins, Sarah A; Vawdrey, David K; Kukafka, Rita; Kuperman, Gilad J

    2011-12-01

    Healthcare delivery organizations are increasingly using online personal health records (PHRs) to provide patients with direct access to their clinical information; however, there may be a lack of consistency in the data made available. We aimed to understand the general use and functionality of PHRs and the organizational policies and decision-making structures for making data available to patients. A cross-sectional survey was administered by telephone structured interview to 21 organizations to determine the types of data made available to patients through PHRs and the presence of explicit governance for PHR data release. Organizations were identified based on a review of the literature, PHR experts, and snowball sampling. Organizations that did not provide patients with electronic access to their data via a PHR were excluded. Interviews were conducted with 17 organizations for a response rate of 81%. Half of the organizations had explicit governance in the form of a written policy that outlined the data types made available to patients. Overall, 88% of the organizations used a committee structure for the decision-making process and included senior management and information services. All organizations sought input from clinicians. Discussion There was considerable variability in the types of clinical data and the time frame for releasing these data to patients. Variability in data release policies may have implications for PHR use and adoption. Future policy activities, such as requirement specification for the latter stages of Meaningful Use, should be leveraged as an opportunity to encourage standardization of functionality and broad deployment of PHRs.

  4. The ecology of work and health: Research and policy directions for the promotion of employee health

    OpenAIRE

    Stokols, D; Pelletier, KR; Fielding, JE

    1996-01-01

    This article identifies new research and policy directions for the field of worksite health in the context of the changing American workplace. These directions are viewed from an ecological perspective on worksite health and are organized around three major themes: (1) the joint influence of physical and social environmental factors on occupational health, (2) the effects of nonoccupational settings (e.g., households, the health care system) on employee well-being and the implications of rece...

  5. Agricultural price and income policy in the EC : alternative policies and their implications

    NARCIS (Netherlands)

    Meester, G.

    1980-01-01

    Alternative forms of income policy without direct supply control. Alternative forms of income policy with direct supply control: quota arrangements. The influence of EC policy on the world market prices of agricultural produce

  6. Direct effect of gonadal and contraceptive steroids on insulin release from mouse pancreatic islets in organ culture

    DEFF Research Database (Denmark)

    Nielsen, Jens Høiriis

    1984-01-01

    Sex steroids are supposed to contribute to the normal glucose homeostasis and to the altered glucose and insulin metabolism in pregnancy and during contraception. In the present study isolated mouse pancreatic islets were maintained in tissue culture medium RPMI 1640 supplemented with 0.5% newborn...... calf serum and 100 ng/ml of one of the following steroids: oestradiol, progesterone, testosterone, megestrol acetate, medroxyprogesterone, chlormadinone acetate, norethynodrel, norethindrone acetate, and ethynyloestradiol. Release of insulin to the culture medium was measured during a 2 week culture...... in the presence of oestradiol, progesterone, or testosterone were subjected to 30 min stimulation with 5.5, 11, 22 mmol/l glucose, only the progesterone-treated islets released more insulin in response to glucose than the control islets. It is concluded that progesterone and its derivatives have a direct effect...

  7. Country policy profile - Slovakia. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Slovakia is 14%, whereas in 2012 it reached 10,6%. The Slovak Republic uses a feed-in tariff system in the promotion of renewable electricity. Energy companies are obliged to purchase and pay for electricity transmitted to the grid. Renewable energy utilization is furthermore incentivised in a form of exemption from excise tax. Currently the Slovak Republic conducts a professional training programme for RES-installers and there are RES-H building obligations. This report monitors the policy changes after the release of the 2013 Progress Report for Slovakia and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  8. Country policy profile - Slovakia. April 2015

    International Nuclear Information System (INIS)

    2015-04-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Slovakia is 14%, whereas in 2012 it reached 10,6%. The Slovak Republic uses a feed-in tariff system in the promotion of renewable electricity. Energy companies are obliged to purchase and pay for electricity transmitted to the grid. Renewable energy utilization is furthermore incentivised in a form of exemption from excise tax. Currently the Slovak Republic conducts a professional training programme for RES-installers and there are RES-H building obligations. This report monitors the policy changes after the release of the 2013 Progress Report for Slovakia and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  9. U.S. nuclear policy, strategy, and force structure: insights and issues from the 1994, 2001, and 2010 nuclear posture reviews

    OpenAIRE

    Lyons, Marco J.

    2014-01-01

    Approved for public release; distribution is unlimited This thesis examines the main decisions taken in the 1994, 2001, and 2010 Nuclear Posture Reviews regarding U.S. nuclear capabilities and declaratory strategy, and the policy debates that followed the publication of each NPR, focusing on deterrence and other objectives of U.S. national security strategy. It analyzes and compares the post–Cold War NPRs to understand how each administration attempted to shape and direct policy, and how k...

  10. Effectiveness of US state policies in reducing CO2 emissions from power plants

    Science.gov (United States)

    Grant, Don; Bergstrand, Kelly; Running, Katrina

    2014-11-01

    President Obama's landmark initiative to reduce the CO2 emissions of existing power plants, the nation's largest source of greenhouse gas (GHG) pollutants, depends heavily on states and their ability to devise policies that meet the goals set by the Environmental Protection Agency (EPA). Under the EPA's proposed Clean Power Plan, states will be responsible for cutting power plants' carbon pollution 30% from 2005 levels by 2030. States have already adopted several policies to reduce the electricity sector's climate impact. Some of these policies focus on reducing power plants' CO2 emissions, and others address this outcome in a more roundabout fashion by encouraging energy efficiency and renewable energy. However, it remains unclear which, if any, of these direct and indirect strategies actually mitigate plants' emissions because scholars have yet to test their effects using plant-level emission data. Here we use a newly released data source to determine whether states' policies significantly shape individual power plants' CO2 emissions. Findings reveal that certain types of direct strategy (emission caps and GHG targets) and indirect ones (public benefit funds and electric decoupling) lower plants' emissions and thus are viable building blocks of a federal climate regime.

  11. Relapse to smoking following release from smoke-free correctional facilities in Queensland, Australia.

    Science.gov (United States)

    Puljević, Cheneal; de Andrade, Dominique; Coomber, Ross; Kinner, Stuart A

    2018-06-01

    Smoke-free prison policies are increasingly common, but few studies have investigated relapse to smoking after release from prison. This study investigated return to tobacco smoking and correlates of smoking at reduced levels after release among adults recently released from smoke-free prisons in Queensland, Australia. A cross-sectional survey of 114 people at parole offices within two months of release from prison was used. The survey measured health, social, and criminological factors related to tobacco smoking. We used logistic regression to identify factors associated with reduced post-release smoking levels compared to pre-incarceration levels. 94% of participants relapsed to smoking within two months of release; 72% relapsed on the day of release. 62% of participants smoked significantly less per day after compared with before incarceration. Living with a partner (Odds Ratio (OR) 2.77, 95%CI 1.02-7.52), expressing support for smoke-free prison policies (OR 2.44, 95%CI 1.12-5.32), intending to remain abstinent post-release (OR 4.29, 95%CI 1.88-9.82), and intending to quit in the future (OR 3.88, 95%CI 1.66-9.07) were associated with reduced smoking post-release. Use of illicit drugs post-release was negatively associated with reduced smoking post-release (OR 0.27, 95%CI 0.09-0.79). In multivariate analyses, pre-release intention to remain smoke-free was associated with reduced smoking post-release (AOR 2.69, 95%CI 1.01-7.14). Relapse to smoking after release from smoke-free prisons is common, but many who relapse smoke less than before incarceration, suggesting that smoke-free prison policies may reduce post-release tobacco smoking. There is a need for tailored, evidence-based tobacco cessation interventions for people recently released from prison. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. Hanford Environmental Dose Reconstruction Project independent direction and oversight

    International Nuclear Information System (INIS)

    Blazek, M.L.; Power, M.

    1991-01-01

    Hanford was selected in 1942 as one of the sites for the Manhattan Project. It produced plutonium for one of the world's first nuclear weapons. The US Department of Energy (DOE) and its predecessors continued to make plutonium for nuclear weapons at Hanford for more than four decades. In the early days of Hanford operations, radioactive materials routinely were released to the environment by many processes. The DOE disclosed documents about these releases in 1986. In 1987, Washington, Oregon, and regional Indian tribes gathered an independent panel of experts. This group recommended dose reconstruction and health effects feasibility studies. Later that year, DOE hired Battelle Pacific Northwest Laboratory (PNL) to reconstruct potential public radiation doses from Hanford's past releases of radioactive material. The DOE agreed with the states and tribes that project direction would come from an independent technical steering panel (TSP). This approach was critical to gain public credibility for the project and the science. The TSP directs the project and makes policy. That is now clear - but, it was hard-earned. Conducting science in an open public process is new, challenging, and clearly worthwhile. The panel's product is good science that is believed and accepted by the public - our client

  13. Development of New Gonadotropin-Releasing Hormone-Modified Dendrimer Platforms with Direct Antiproliferative and Gonadotropin Releasing Activity.

    Science.gov (United States)

    Varamini, Pegah; Rafiee, Amirreza; Giddam, Ashwini Kumar; Mansfeld, Friederike M; Steyn, Frederik; Toth, Istvan

    2017-10-26

    Gonadotropin-releasing hormone (GnRH) agonists (e.g., triptorelin) are used for androgen suppression therapy. They possess improved stability as compared to the natural GnRH, yet they suffer from a poor pharmacokinetic profile. To address this, we used a GnRH peptide-modified dendrimer platform with and without lipidation strategy. Dendrimers were synthesized on a polylysine core and bore either native GnRH (1, 2, and 5) or lipid-modified GnRH (3 and 4). Compound 3, which bore a lipidic moiety in a branched tetramer structure, showed approximately 10-fold higher permeability and metabolic stability and 39 times higher antitumor activity against hormone-resistant prostate cancer cells (DU145) relative to triptorelin. In gonadotropin-release experiments, dendrimer 3 was shown to be the most potent construct. Dendrimer 3 showed similar luteinizing hormone (LH)-release activity to triptorelin in mice. Our findings indicate that dendrimer 3 is a promising analog with higher potency for the treatment of hormone-resistant prostate cancer than the currently available GnRH agonists.

  14. Dormancy release and flowering time in Ziziphus jujuba Mill., a "direct flowering" fruit tree, has a facultative requirement for chilling.

    Science.gov (United States)

    Meir, Michal; Ransbotyn, Vanessa; Raveh, Eran; Barak, Simon; Tel-Zur, Noemi; Zaccai, Michele

    2016-03-15

    In deciduous fruit trees, the effect of chilling on flowering has mostly been investigated in the "indirect flowering" group, characterized by a period of rest between flower bud formation and blooming. In the present study, we explored the effects of chilling and chilling deprivation on the flowering of Ziziphus jujuba, a temperate deciduous fruit tree belonging to the "direct flowering" group, in which flower bud differentiation, blooming and fruit development occur after dormancy release, during a single growing season. Dormancy release, vegetative growth and flowering time in Z. jujuba cv. Ben-Li were assessed following several treatments of chilling. Chilling treatments quantitatively decreased the timing of vegetative bud dormancy release, thereby accelerating flowering, but had no effect on the time from dormancy release to flowering. Trees grown at a constant temperature of 25°C, without chilling, broke dormancy and flowered, indicating the facultative character of chilling in this species. We measured the expression of Z. jujuba LFY and AP1 homologues (ZjLFY and ZjAP1). Chilling decreased ZjLFY expression in dormant vegetative buds but had no effect on ZjAP1expression, which reached peak expression before dormancy release and at anthesis. In conclusion, chilling is not obligatory for dormancy release of Z. jujuba cv. Ben-Li vegetative buds. However, the exposure to chilling during dormancy does accelerate vegetative bud dormancy release and flowering. Copyright © 2016 Elsevier GmbH. All rights reserved.

  15. The Effect of the Common Agricultural Policy Reform by 2013 on Direct Payments in Relation to Animal Welfare in the European Union - Review

    Directory of Open Access Journals (Sweden)

    Marek Angelovič

    2011-10-01

    Full Text Available The primary role of agriculture is to provide food and the European Union should be able to contribute to rising world food demand. The Common Agriculture Policy covers the wide variety of measures used to support and protect the European Union farmers. The most important measure within the Common Agriculture Policy is direct payments paid directly to farmers to protect their income. The Common Agriculture Policy is due to be reformed by 2013. The main object of the Common Agriculture Policy, which is a provision of safe, healthy choice of food at transparent and affordable prices, will remain unchanged, but further changes of the Common Agriculture Policy are necessary to respond to the new challenges such as animal welfare, global food security, natural resources such as water, air, biodiversity and soil, climate changes, increasing globalization and rising price volatility.

  16. Economic reform in Vietnam - the role of foreign direct investment and trade policy

    International Nuclear Information System (INIS)

    Tran, D.L.

    1998-11-01

    Vietnam was one of the five poorest countries in the world in the 1980's. Since then, Vietnam has adopted a market economic policy, and she has made substantial economic progress. In the last 10 years Meanwhile Vietnam's per capita income has increased by 3 times, the volume of export doubled very two years, and the inflation rate was reduced to 4.5 % in 1997 from 775 % in 1986. The GDP also has increased, the exchange rate with the US$ was stabilized and foreign direct investment (FDI) and trade has increased. There was about US$35 billion were invested by the foreign investors between 1987 to the middle of June 1998. However, the current crisis in the economies of Southeast Asian countries has put pressure on Vietnam to rethink seriously her future reform program with respect to stabilization and sustainable current economic policies. Since FDI is an imperative for the development of a country like Vietnam, it is necessary to use this capital very careful for her economy. Thus, the main objective of this dissertation is to study the role of FDI in the development of Vietnam. To examine this objective, various investigations were made, especially focusing on development dimensions such as reforming state enterprises, foreign trade policy, foreign investment and so on. Therefore, in the future, FDI and privatization policies should be strengthened to maintain and create an international market. Moreover, there are some major reforms required to transform the state sector into a private sector with appropriate policy measures, such as improving management of financial companies, developing the agricultural sector and minimizing bureaucracy and red tapism of the government. This dissertation provides a set of recommendations how to strengthen Vietnams economic and market situation in the 21st century. (author)

  17. Directionality across Diversity: Governing Contending Policy Rationales in the Transition towards the Bioeconomy

    Directory of Open Access Journals (Sweden)

    Lisa Scordato

    2017-02-01

    Full Text Available Although the bioeconomy has been embraced by many governments around the world as a way of responding to the grand challenge of climate change, it remains unclear what the bioeconomy is and how it can contribute to achieving these broad policy objectives. The aim of this paper is to improve our understanding of whether, and how, the bioeconomy includes contending rationales for governance and policy-making. In order to do this, we apply a typology of three bioeconomy visions onto the policy discourse on the bioeconomy. These visions are (1 a bio-technology vision; (2 a bio-resource vision; and (3 a bio-ecology vision. Based on a discourse analysis of 41 submissions to a public hearing on the development of a bioeconomy strategy in Norway, the paper explores the actors involved in shaping the new bioeconomy and analyses their positions on this emerging field. The paper finds that it is possible to categorise the consultative inputs into these three visions, and also that the bio-resource vision is predominant, which reflects the structure of the national economy. Moreover, the paper reflects upon how the contending visions observed imply negotiations and power struggles, which may hamper directionality in the current socio-technical transition.

  18. Law project on the energy policy direction; Projet de loi d'orientation sur l'energie

    Energy Technology Data Exchange (ETDEWEB)

    Raffarin, J.P.; Sarkozy, N

    2004-05-01

    The law of the energy direction aims to define, in the first article, the objectives and the directions of the french energy policy and to complete the today dispositions in matter of energy. The first part is devoted to the energy demand control and presents a system of energy saving certificates, the thermal regulation increasing of buildings and a better information of the consumers. The second part promotes the renewable energies development. (A.L.B.)

  19. 25 CFR 900.5 - Effect of these regulations on Federal program guidelines, manual, or policy directives.

    Science.gov (United States)

    2010-04-01

    ... SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT General Provisions § 900.5 Effect of these regulations... 25 Indians 2 2010-04-01 2010-04-01 false Effect of these regulations on Federal program guidelines, manual, or policy directives. 900.5 Section 900.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE...

  20. 42 CFR 93.100 - General policy.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false General policy. 93.100 Section 93.100 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

  1. Enacting Policy: The Capacity of School Leaders to Support Early Career Teachers through Policy Work

    Science.gov (United States)

    Sullivan, Anna M.; Morrison, Chad

    2014-01-01

    Early career teachers often feel overwhelmed by the complex, intense and unpredictable nature of their work. Recently, policy initiatives have been introduced to provide new teachers with extra release-time from face-to-face classroom teaching duties to assist them in their transition to the workforce. This paper reports on a critical policy study…

  2. Analysis of Department of Defense social media policy and its impact on operational security

    OpenAIRE

    Leonhardi, Eric V.; Murphy, Mark; Kim, Hannah

    2015-01-01

    Approved for public release; distribution is unlimited The emergence and rapid adoption of social media by society has forced the Department of Defense (DOD) to adapt, and ultimately develop and incorporate, social media policy into its cybersecurity strategy. While social media has influenced DOD strategy, it has also had a direct impact on the organization’s operational security (OPSEC). DOD personnel using social media represent a potential OPSEC risk through the various ways and means ...

  3. The End of the Deterrence Paradigm? Future Directions for Global Refugee Policy

    Directory of Open Access Journals (Sweden)

    Thomas Gammeltoft-Hansen

    2017-02-01

    facilitating irregular migration grows, unfortunately so too do attempts to exploit migrants and refugees by smugglers, criminal networks, governments, or members of local communities (Gammeltoft-Hansen and Nyberg Sørensen 2013. The “deterrence paradigm” can be understood as a particular instantiation of the global refugee protection regime. It shows how deterrence policies have come to dominate responses to  asylum seekers arriving in developed states, and how such policies have continued to develop in response to changes in migration patterns as well as legal impositions. The dominance of the deterrence paradigm also explains the continued reliance on deterrence as a response to the most recent “crisis,” despite continued calls from scholars and civil society for a more protection-oriented and sustainable response. The paper argues that the current “crisis,” more than a crisis in terms of refugee numbers and global protection capacity, should be seen a crisis in terms of the institutionalized responses so far pursued by states. Deterrence policies are being increasingly challenged, both by developments in international law and by less wealthy states left to shoulder the vast majority of the world’s refugees. At the same time, recent events suggest that deterrence policies may not remain an effective tool to prevent secondary movement of refugees in the face of rising global protection needs, while deterrence involves increasing direct and indirect costs for the states involved. The present situation may thus be characterized as, or at least approaching, a period of paradigm crisis, and we may be seeing the beginning of the end for deterrence as a dominant policy paradigm in regard to global refugee policy. In its place, a range of more or less developed alternative policy frameworks are currently competing, though so far none of them appear to have gained sufficient traction to initiate an actual paradigm shift in terms of global refugee policy. Nonetheless

  4. Drug release kinetic analysis and prediction of release data via polymer molecular weight in sustained release diltiazem matrices.

    Science.gov (United States)

    Adibkia, K; Ghanbarzadeh, S; Mohammadi, G; Khiavi, H Z; Sabzevari, A; Barzegar-Jalali, M

    2014-03-01

    This study was conducted to investigate the effects of HPMC (K4M and K100M) as well as tragacanth on the drug release rate of diltiazem (DLTZ) from matrix tablets prepared by direct compression method.Mechanism of drug transport through the matrices was studied by fitting the release data to the 10 kinetic models. 3 model independent parameters; i. e., mean dissolution time (MDT), mean release rate (MRR) and release rate efficacy (RE) as well as 5 time point approaches were established to compare the dissolution profiles. To find correlation between fraction of drug released and polymer's molecular weight, dissolution data were fitted into two proposed equations.All polymers could sustain drug release up to 10 h. The release data were fitted best to Peppas and Higuchi square root kinetic models considering squared correlation coefficient and mean percent error (MPE). RE and MRR were decreased when polymer to drug ratio was increased. Conversely, t60% was increased with raising polymer /drug ratio. The fractions of drug released from the formulations prepared with tragacanth were more than those formulated using the same amount of HPMC K4M and HPMC K100M.Preparation of DLTZ matrices applying HPMCK4M, HPMC K100M and tragacanth could effectively extend the drug release. © Georg Thieme Verlag KG Stuttgart · New York.

  5. Strategic environmental noise mapping: methodological issues concerning the implementation of the EU Environmental Noise Directive and their policy implications.

    LENUS (Irish Health Repository)

    Murphy, E

    2010-04-01

    This paper explores methodological issues and policy implications concerning the implementation of the EU Environmental Noise Directive (END) across Member States. Methodologically, the paper focuses on two key thematic issues relevant to the Directive: (1) calculation methods and (2) mapping methods. For (1), the paper focuses, in particular, on how differing calculation methods influence noise prediction results as well as the value of the EU noise indicator L(den) and its associated implications for comparability of noise data across EU states. With regard to (2), emphasis is placed on identifying the issues affecting strategic noise mapping, estimating population exposure, noise action planning and dissemination of noise mapping results to the general public. The implication of these issues for future environmental noise policy is also examined.

  6. EPICS release 3.11 specific documentation -- EPICS release notes for 3.11

    International Nuclear Information System (INIS)

    1994-01-01

    EPICS release 3.11 is now ready for user testing. A person who wants to set up a simplified application environment to boot an IOC and create databases using R3.11 should follow the directions in Appendix B, page 27, of the EPICS Source/Release Control Manual, Sept. 20, 1993. The R3.11 EPICS path at ANL/APS is /net/phebos/epics/R3.11 so the command to get the new release is /net/phebos/epics/R3.11/Unix/share/bin/getrel /net/phebos/epics/R3.11. An existing R3.8 short form report can be copied to this new directory and used to create a database. ANL/APS is currently testing an Application Developers Source/Release control system. It is not yet ready for general distribution. Attached are the EPICS R3.11 release notes

  7. Laws, directives and policy instruments important for the development of the waste management system; Lagar, direktiv och styrmedel viktiga foer avfallssystemets utveckling

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, Karolina; Sundberg, Johan

    2010-01-15

    This report gives a survey and a description of present and future policy instruments that have been or will become important for the development of the waste management system. Policy instruments here refers to laws, directives, taxes/fees, national/local goals and other regulating measures that the society introduce to steer the development of the waste management system. This work can thus be used as a dictionary or a guideline for these measures. The investigation has two goals: 1. To give representatives of the Swedish waste management system a summary of important policy instruments for the future development of the waste management system. 2. To give Waste Refinery a summary of these policy instruments that can be used for the discussions of how the research within the centre should develop during stage 2. A large number of policy instruments have been found during the study. These instruments have been, most likely will become, or may become important for the development of the waste management system. Most of them are described in this report. The selection made is presented in Table 1. Focus for the selection has been policy instruments that are important for the research activities within Waste Refinery, meaning policy instruments that direct or indirect can change the use of thermal and/or biological treatment as well as techniques and methods supporting these treatment methods. [Table 1. Policy instruments that are presented in the report

  8. England Policy in Gifted Education: Current Problems and Promising Directions

    Science.gov (United States)

    Koshy, Valsa; Smith, Carole Portman; Casey, Ronald

    2018-01-01

    This article presents and analyzes policies in identification and provisions in England with respect to gifted education. England has developed a national policy to provide services to identified students. Surveys and interviews with teachers illustrate how implementation of both identification and provision policy elements were handled. Although…

  9. Social determinants of health in selected slum areas in Jordan: challenges and policy directions.

    Science.gov (United States)

    Ajlouni, Musa T

    2016-01-01

    The unplanned urbanization in Jordan has over time created many informal settlements "slums" around big cities as Amman, Zerka and Aqaba. The purpose of this study was to highlight the most common challenges related to social determinants of health in two selected slum areas in Amman and Aqaba and suggest policy directions and interventions to meet these challenges. In addition to a prestructured interview with all household heads living in the two slum sites, focus group meetings with a purposefully selected sample of 12 slum dwellers in each site were used to assess the structural and intermediary determinants of health as perceived by slum residents in the two study locations. The study found that slum residents in the two locations suffer from many challenges as severe poverty; unemployment; illiteracy and low education attainments; gender discrimination; insufficient and poor diet; social and official exclusion; unhealthy environment; lack of water supply, electricity and basic sanitation facilities; high prevalence of diseases; and insufficient and inappropriate health services. Specific policy directions to meet these challenges were recommended and grouped into three main clusters: social protection, social inclusion and empowerment. New plans and tools should be developed by local authorities in Jordan to understand, protect, include and empower those vulnerable people who are forced to live in these unhealthy and inhuman environments. Copyright © 2014 John Wiley & Sons, Ltd.

  10. Direct conversion from tramadol to tapentadol prolonged release for moderate to severe, chronic malignant tumour-related pain.

    Science.gov (United States)

    Kress, H G; Koch, E D; Kosturski, H; Steup, A; Karcher, K; Dogan, C; Etropolski, M; Eerdekens, M

    2016-10-01

    A recent randomized-withdrawal, active- and placebo-controlled, double-blind phase 3 study showed that tapentadol prolonged release (PR) was effective and well tolerated for managing moderate to severe, chronic malignant tumour-related pain in patients who were opioid naive or dissatisfied with current treatment (Pain Physician, 2014, 17, 329-343). This post hoc, subgroup analysis evaluated the efficacy and tolerability of tapentadol PR in patients who previously received and were dissatisfied with tramadol for any reason and who had a pain intensity ≥5 (11-point numerical rating scale) before converting directly to tapentadol PR. In the original study, eligible patients had been randomized (2:1) and titrated to their optimal dose of tapentadol PR (100-250 mg bid) or morphine sulphate-controlled release (40-100 mg bid) over 2 weeks. The present report focuses on results during the titration period for a subgroup of patients randomized to tapentadol PR after having been on tramadol treatment prior to randomization in the study (n = 129). Results for this subgroup are compared with results for all 338 patients who received tapentadol PR during titration (overall tapentadol PR group). Responder rates (responders: completed titration, mean pain intensity pain could safely switch from prior treatment with the weak centrally acting analgesic tramadol directly to the strong centrally acting analgesic tapentadol PR, for an improved analgesic therapy for severe pain. WHAT DOES THIS STUDY ADD?: Results of this post hoc analysis show that patients who had received prior tramadol therapy could switch directly to tapentadol PR, with the majority (˜70%) experiencing improved efficacy. © 2016 The Authors. European Journal of Pain published by John Wiley & Sons Ltd on behalf of European Pain Federation - EFIC®.

  11. Innovations in climate policy: conclusions and new directions

    OpenAIRE

    Jordan, A.; Huitema, D.

    2014-01-01

    Academics and practitioners have responded to the gridlock in the international climate-change regime by more actively exploring the ability of individuals and/or groups of states to fill in the associated ‘governance gaps’ by engaging in policy innovation at the level of the nation state, including its regional and local emanations. Here, we draw together the findings of a collection that, for the first time, explores policy innovation at this level from three key perspectives: the source of...

  12. Canadian pollutant releases and transfers : NPRI data 1998

    International Nuclear Information System (INIS)

    2001-03-01

    A large, two-sided fold-out poster showing pollution hotspots throughout Canada, has been released by the Canadian Institute for Environmental Law and Policy (CIELAP). The poster is based on the maps and tables of the National Pollutant Release Inventory (NPRI) 1998. It presents the top on-site releases and off-site transfers of pollutants by facilities across Canada, and provides a summary of releases, transfers and recycling of pollutants by province. The map depicts the facilities with the five largest quantities of individual pollutants released to each medium, i. e. water, air, land, underground. The crude oil and gas, other utilities, primary metal, paper and chemical industrial sectors are responsible for the largest on-site releases, while the business services, fabricated metal. primary metal and chemical industrial sectors account for the largest off-site transfers. Twenty-five of the 176 substances whose releases and transfers are reported under the NPRI are classified as 'toxic' or 'carcinogenic'. tabs., maps

  13. Assessment of Direct-to-Consumer Genetic Testing Policy in Korea Based on Consumer Preference.

    Science.gov (United States)

    Jeong, Gicheol

    2017-01-01

    In June 2016, Korea permitted direct-to-consumer genetic testing (DTC-GT) on 42 genes. However, both the market and industry have not yet been fully activated. Considering the aforementioned context, this study provides important insights. The Korean DTC-GT policy assessment is based on consumer preference analysis using a discrete choice experiment. In August 2016, a web-based survey was conducted to collect data from 1,200 respondents. The estimation results show that consumers prefer a DTC-GT product that is cheap, tests various items or genes, offers accurate test results, and guarantees the confidentiality of all information. However, consumers are not entirely satisfied by current DTC-GT products due to the existence of insufficient and/or inadequate policies. First, the permitted testing of 42 genes is insufficient to satisfy consumers' curiosity regarding their genes. Second, the accuracy of the DTC-GT products has not been fully verified, assessed, and communicated to consumers. Finally, regulatory loopholes that allow information leaks in the DTC-GT process can occur. These findings imply that DTC-GT requires an improvement in government policy-making criteria and the implementation of practical measures to guarantee test accuracy and genetic information. © 2017 S. Karger AG, Basel.

  14. BASES OF PUBLIC POLICY FORMATION DIRECTED AT ENSURING BUDGET SECURITY

    Directory of Open Access Journals (Sweden)

    S. Onishchenko

    2015-03-01

    Full Text Available In the article the priorities and public policies that can improve the safety level of the budget of Ukraine have been grounded. Attention on the problems of imbalance and deficiency trends accumulation of public debt has been focused. The detailed analysis of the budget deficit of the European community to further research the main problems of fiscal security has been carried out. The formation of the concept of budget policy should include long-term and medium-term priorities of the state priorities areas have been concluded. Budget policy on public debt must deal with interrelated issues of debt bondage and effective use of public credit, promote economic growth with respect safe level and structure of public debt have been emphasized by author. Debt policy as part of fiscal policy under certain conditions can be a powerful tool to intensify investment and innovation processes in society, promote economic and social development. The reorientation of fiscal policy to address current problems through debt and use it as the basis of investment and innovation development provides an effective public debt management is designed to reduce state budget expenditures on its servicing and repayment, optimizing the scope and structure of debt according to economic growth. The role of debt policy in modern terms increases is clearly subordinate to and consistent with long-term goals and priorities of fiscal policy. There is an urgent development and implementation of effective mechanisms for investing borrowed resources, increasing the efficiency of public investment, including the improvement of organizational, financial, legal and controls. Strategically budget security guarantees only competitive economy, which can be constructed only by recovery and accelerated development of promising sectors of the national economy in the presence of a balanced budget policy. Now there is a tendency to implement only measures to stabilize the political and socio

  15. Strategic environmental noise mapping: methodological issues concerning the implementation of the EU Environmental Noise Directive and their policy implications.

    Science.gov (United States)

    Murphy, E; King, E A

    2010-04-01

    This paper explores methodological issues and policy implications concerning the implementation of the EU Environmental Noise Directive (END) across Member States. Methodologically, the paper focuses on two key thematic issues relevant to the Directive: (1) calculation methods and (2) mapping methods. For (1), the paper focuses, in particular, on how differing calculation methods influence noise prediction results as well as the value of the EU noise indicator L(den) and its associated implications for comparability of noise data across EU states. With regard to (2), emphasis is placed on identifying the issues affecting strategic noise mapping, estimating population exposure, noise action planning and dissemination of noise mapping results to the general public. The implication of these issues for future environmental noise policy is also examined. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

  16. Interaction of the EU emissions Trading Directive with climate policy instrument in the Netherlands. Policy Brief

    International Nuclear Information System (INIS)

    Sijm, J.P.M.

    2003-11-01

    This policy brief presents an overview of the implications of the proposed EU Emissions Trading Scheme (EU ETS) for some selected energy and climate policy instruments in the Netherlands. It summarises the results of research that has been conducted by the Energy research Centre of the Netherlands (ECN) as part of the EU-funded project Interaction in EU Climate Policy

  17. Modelling the effect of injection pressure on heat release parameters and nitrogen oxides in direct injection diesel engines

    Directory of Open Access Journals (Sweden)

    Yüksek Levent

    2014-01-01

    Full Text Available Investigation and modelling the effect of injection pressure on heat release parameters and engine-out nitrogen oxides are the main aim of this study. A zero-dimensional and multi-zone cylinder model was developed for estimation of the effect of injection pressure rise on performance parameters of diesel engine. Double-Wiebe rate of heat release global model was used to describe fuel combustion. extended Zeldovich mechanism and partial equilibrium approach were used for modelling the formation of nitrogen oxides. Single cylinder, high pressure direct injection, electronically controlled, research engine bench was used for model calibration. 1000 and 1200 bars of fuel injection pressure were investigated while injection advance, injected fuel quantity and engine speed kept constant. The ignition delay of injected fuel reduced 0.4 crank angle with 1200 bars of injection pressure and similar effect observed in premixed combustion phase duration which reduced 0.2 crank angle. Rate of heat release of premixed combustion phase increased 1.75 % with 1200 bar injection pressure. Multi-zone cylinder model showed good agreement with experimental in-cylinder pressure data. Also it was seen that the NOx formation model greatly predicted the engine-out NOx emissions for both of the operation modes.

  18. A Comparative Study on the Lot Release Systems for Vaccines as of 2016.

    Science.gov (United States)

    Fujita, Kentaro; Naito, Seishiro; Ochiai, Masaki; Konda, Toshifumi; Kato, Atsushi

    2017-09-25

    Many countries have already established their own vaccine lot release system that is designed for each country's situation: while the World Health Organization promotes for the convergence of these regulatory systems so that vaccines of assured quality are provided globally. We conducted a questionnaire-based investigation of the lot release systems for vaccines in 7 countries and 2 regions. We found that a review of the summary protocol by the National Regulatory Authorities was commonly applied for the independent lot release of vaccines, however, we also noted some diversity between countries, especially in regard to the testing policy. Some countries and regions, including Japan, regularly tested every lot of vaccines, whereas the frequency of these tests was reduced in other countries and regions as determined based on the risk assessment of these products. Test items selected for the lot release varied among the countries or regions investigated, although there was a tendency to prioritize the potency tests. An understanding of the lot release policy may contribute to improving and harmonizing the lot release system globally in the future.

  19. Analysis of Silicones Released from Household Items and Baby Articles by Direct Analysis in Real Time-Mass Spectrometry

    Science.gov (United States)

    Gross, Jürgen H.

    2015-03-01

    Direct analysis in real time-mass spectrometry (DART-MS) enables screening of articles of daily use made of polydimethylsiloxanes (PDMS), commonly known as silicone rubber, to assess their tendency to release low molecular weight silicone oligomers. DART-MS analyses were performed on a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. Flexible silicone baking molds, a watch band, and a dough scraper, as baby articles different brands of pacifiers, nipples, and a teething ring have been examined. While somewhat arbitrarily chosen, the set can be regarded as representative of household items, baby articles, and other objects made of silicone rubber. For comparison, two brands of silicone septa and as blanks a glass slide and a latex pacifier were included. Differences between the objects were mainly observed in terms of molecular weight distribution and occasional release of other compounds in addition to PDMS. Other than that, all objects made of silicone rubber released significant amounts of PDMS during DART analysis. To provide a coarse quantification, a calibration based on silicone oil was established, which delivered PDMS losses from 20 μg to >100 μg during the 16-s period per measurement. Also, the extraction of baking molds in rapeseed oil demonstrated a PDMS release at the level of 1 μg mg-1. These findings indicate a potential health hazard from frequent or long-term use of such items. This work does not intend to blame certain brands of such articles. Nonetheless, a higher level of awareness of this source of daily silicone intake is suggested.

  20. Investigating the in vitro drug release kinetics from controlled release diclofenac potassium-ethocel matrix tablets and the influence of co-excipients on drug release patterns.

    Science.gov (United States)

    Shah, Shefaat Ullah; Shah, Kifayat Ullah; Rehman, Asimur; Khan, Gul Majid

    2011-04-01

    The objective of the study was to formulate and evaluate controlled release polymeric tablets of Diclofenac Potassium for the release rate, release patterns and the mechanism involved in the release process of the drug. Formulations with different types and grades of Ethyl Cellulose Ether derivatives in several drug-to-polymer ratios (D:P) were compressed into tablets using the direct compression method. In vitro drug release studies were performed in phosphate buffer (pH 7.4) as dissolution medium by using USP Method-1 (Rotating Basket Method). Similarity factor f2 and dissimilarity factor f1 were applied for checking the similarities and dissimilarities of the release profiles of different formulations. For the determination of the release mechanism and drug release kinetics various mathematical/kinetic models were employed. It was found that all of the Ethocel polymers could significantly slow down the drug release rate with Ethocel FP polymers being the most efficient, especially at D:P ratios of 10:03 which lead towards the achievement of zero or near zero order release kinetics.

  1. Performance and efficiency evaluation and heat release study of a direct-injection stratified-charge rotary engine

    Science.gov (United States)

    Nguyen, H. L.; Addy, H. E.; Bond, T. H.; Lee, C. M.; Chun, K. S.

    1987-01-01

    A computer simulation which models engine performance of the Direct Injection Stratified Charge (DISC) rotary engines was used to study the effect of variations in engine design and operating parameters on engine performance and efficiency of an Outboard Marine Corporation (OMC) experimental rotary combustion engine. Engine pressure data were used in a heat release analysis to study the effects of heat transfer, leakage, and crevice flows. Predicted engine data were compared with experimental test data over a range of engine speeds and loads. An examination of methods to improve the performance of the rotary engine using advanced heat engine concepts such as faster combustion, reduced leakage, and turbocharging is also presented.

  2. Data Sharing For Precision Medicine: Policy Lessons And Future Directions.

    Science.gov (United States)

    Blasimme, Alessandro; Fadda, Marta; Schneider, Manuel; Vayena, Effy

    2018-05-01

    Data sharing is a precondition of precision medicine. Numerous organizations have produced abundant guidance on data sharing. Despite such efforts, data are not being shared to a degree that can trigger the expected data-driven revolution in precision medicine. We set out to explore why. Here we report the results of a comprehensive analysis of data-sharing guidelines issued over the past two decades by multiple organizations. We found that the guidelines overlap on a restricted set of policy themes. However, we observed substantial fragmentation in the policy landscape across specific organizations and data types. This may have contributed to the current stalemate in data sharing. To move toward a more efficient data-sharing ecosystem for precision medicine, policy makers should explore innovative ways to cope with central policy themes such as privacy, consent, and data quality; focus guidance on interoperability, attribution, and public engagement; and promote data-sharing policies that can be adapted to multiple data types.

  3. Determination of the average number of electrons released during the oxidation of ethanol in a direct ethanol fuel cell

    International Nuclear Information System (INIS)

    Majidi, Pasha; Pickup, Peter G.

    2015-01-01

    The energy efficiency of a direct ethanol fuel cell (DEFC) is directly proportional to the average number of electrons released per ethanol molecule (n-value) at the anode. An approach to measuring n-values in DEFC hardware is presented, validated for the oxidation of methanol, and shown to provide n-values for ethanol oxidation that are consistent with trends and estimates from full product analysis. The method is based on quantitative oxidation of fuel that crosses through the membrane to avoid the errors that would otherwise result from crossover. It will be useful for rapid screening of catalysts, and allows performances (polarization curves) and n-values to be determined simultaneously under well controlled transport conditions.

  4. Environmental policy and technological change: The effects of economic incentives and direct regulation on energy-saving innovation

    Science.gov (United States)

    Newell, Richard G., Jr.

    Over the long run, the impacts of environmental policies will be greatly affected by the influence these policies have on the rate and direction of technological change. In particular, the roles played by energy prices and product regulation in energy-saving technology innovation are exceptionally important considerations in modeling climate change and evaluating alternative policy options. We analyze the effects of energy prices and energy-efficiency regulations on the menu of air conditioner and water heater models available on the market over a period of more than three decades, measuring their innovation in terms of improvements in the products' underlying characteristics. Through estimation of a series of "characteristics transformation surfaces," we find that during less than four decades, substantial innovation in these products reduced the total capital and operating costs of air conditioning by one-half and water heating by more than one-fifth. Although the overall rate of innovation in these products appears to be independent of energy prices and regulations, the evidence suggests that the direction of innovation may be responsive to energy price changes. This would imply that energy price increases induced innovation in a direction that lowered the capital cost tradeoffs inherent in producing more energy-efficient products. The evidence supporting "regulation-induced" changes in these tradeoffs is much weaker. Our estimates indicate that about one- to two-fifths of the energy-efficiency improvements in these products from 1973 to 1993 were associated with historical changes in energy prices. We also find that this responsiveness to price changes increased substantially after product labeling requirements came into effect, and that minimum efficiency standards had a significant positive effect on average efficiency levels. Nonetheless, a sizeable portion of historical efficiency improvements in these technologies is associated with the products' overall

  5. Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors

    Directory of Open Access Journals (Sweden)

    Adriana Bajetto

    2017-10-01

    Full Text Available Glioblastoma (GBM, the most common primary brain tumor in adults, is an aggressive, fast-growing and highly vascularized tumor, characterized by extensive invasiveness and local recurrence. In GBM and other malignancies, cancer stem cells (CSCs are believed to drive invasive tumor growth and recurrence, being responsible for radio- and chemo-therapy resistance. Mesenchymal stem cells (MSCs are multipotent progenitors that exhibit tropism for tumor microenvironment mediated by cytokines, chemokines and growth factors. Initial studies proposed that MSCs might exert inhibitory effects on tumor development, although, to date, contrasting evidence has been provided. Different studies reported either MSC anti-tumor activity or their support to tumor growth. Here, we examined the effects of umbilical cord (UC-MSCs on in vitro GBM-derived CSC growth, by direct cell-to-cell interaction or indirect modulation, via the release of soluble factors. We demonstrate that UC-MSCs and CSCs exhibit reciprocal tropism when co-cultured as 3D spheroids and their direct cell interaction reduces the proliferation of both cell types. Contrasting effects were obtained by UC-MSC released factors: CSCs, cultured in the presence of conditioned medium (CM collected from UC-MSCs, increased proliferation rate through transient ERK1/2 and Akt phosphorylation/activation. Analysis of the profile of the cytokines released by UC-MSCs in the CM revealed a strong production of molecules involved in inflammation, angiogenesis, cell migration and proliferation, such as IL-8, GRO, ENA-78 and IL-6. Since CXC chemokine receptor 2 (CXCR2, a receptor shared by several of these ligands, is expressed in GBM CSCs, we evaluated its involvement in CSC proliferation induced by UC-MSC-CM. Using the CXCR2 antagonist SB225002, we observed a partial but statistically significant inhibition of CSC proliferation and migration induced by the UC-MSC-released cytokines. Conversely, CXCR2 blockade did not

  6. Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors

    Science.gov (United States)

    Bajetto, Adriana; Pattarozzi, Alessandra; Corsaro, Alessandro; Barbieri, Federica; Daga, Antonio; Bosio, Alessia; Gatti, Monica; Pisaturo, Valerio; Sirito, Rodolfo; Florio, Tullio

    2017-01-01

    Glioblastoma (GBM), the most common primary brain tumor in adults, is an aggressive, fast-growing and highly vascularized tumor, characterized by extensive invasiveness and local recurrence. In GBM and other malignancies, cancer stem cells (CSCs) are believed to drive invasive tumor growth and recurrence, being responsible for radio- and chemo-therapy resistance. Mesenchymal stem cells (MSCs) are multipotent progenitors that exhibit tropism for tumor microenvironment mediated by cytokines, chemokines and growth factors. Initial studies proposed that MSCs might exert inhibitory effects on tumor development, although, to date, contrasting evidence has been provided. Different studies reported either MSC anti-tumor activity or their support to tumor growth. Here, we examined the effects of umbilical cord (UC)-MSCs on in vitro GBM-derived CSC growth, by direct cell-to-cell interaction or indirect modulation, via the release of soluble factors. We demonstrate that UC-MSCs and CSCs exhibit reciprocal tropism when co-cultured as 3D spheroids and their direct cell interaction reduces the proliferation of both cell types. Contrasting effects were obtained by UC-MSC released factors: CSCs, cultured in the presence of conditioned medium (CM) collected from UC-MSCs, increased proliferation rate through transient ERK1/2 and Akt phosphorylation/activation. Analysis of the profile of the cytokines released by UC-MSCs in the CM revealed a strong production of molecules involved in inflammation, angiogenesis, cell migration and proliferation, such as IL-8, GRO, ENA-78 and IL-6. Since CXC chemokine receptor 2 (CXCR2), a receptor shared by several of these ligands, is expressed in GBM CSCs, we evaluated its involvement in CSC proliferation induced by UC-MSC-CM. Using the CXCR2 antagonist SB225002, we observed a partial but statistically significant inhibition of CSC proliferation and migration induced by the UC-MSC-released cytokines. Conversely, CXCR2 blockade did not reduce the

  7. Evaluating indirect and direct effects of eco-restoration policy on soil conservation service in Yangtze River Basin.

    Science.gov (United States)

    Kong, Lingqiao; Zheng, Hua; Rao, Enming; Xiao, Yi; Ouyang, Zhiyun; Li, Cong

    2018-08-01

    The conservation impacts of policies that promote large-scale ecological restoration of ecosystem services and socio-economic development are well documented around the world. However, the effect of socio-economic development resulting from such policies on ecosystem services is rarely analysed, although it is important to do so if these policies are to be sustainable. We analysed the socio-economic impacts of soil conservation services from 2000 to 2015 in the Yangtze River Basin under the Grain to Green Programme (GTGP). Also we assessed the driving forces behind the programme: conservation policies, urbanization, agricultural development, and population growth. Our results show that during 2000-2015, cultivated area decreased by 7.5%, urban area increased by 67.5%, forest area increased by 2.1%, and soil erosion was reduced by 19.5%. The programme not only contributed significantly to an improvement in soil conservation services but also enhanced them significantly through faster urbanization. Furthermore, vegetation cover and crop yields increased synergistically, mainly due to high-efficiency agriculture that reduced the negative effect of the GTGP on agricultural production. Overall determining the indirect and direct effects of the GTGP on soil conservation and agricultural production are important for furthering our understanding of the long-term effects of ecological restoration policies, and the present study offers practical insights for ecological restoration of other watersheds. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Sensitivity of the engineered barrier system (EBS) release rate to alternative conceptual models of advective release from waste packages under dripping fractures

    International Nuclear Information System (INIS)

    Lee, J.H.; Atkins, J.E.; McNeish, J.A.; Vallikat, V.

    1996-01-01

    The first model assumed that dripping water directly contacts the waste form inside the ''failed'' waste package and radionuclides are released from the EBS by advection. The second model assumed that dripping water is diverted around the package (because of corrosion products plugging the perforations), thereby being prevented from directly contacting the waste form. In the second model, radionuclides were assumed to diffuse through the perforations, and, once outside the waste package, to be released from the EBS by advection. For the case with the second EBS release model, most radionuclides had lower peak EBS release rates than with the first model. Impacts of the alternative EBS release models were greater for the radionuclides with low solubility. The analysis indicated that the EBS release model representing advection through a ''failed'' waste package (the first model) may be too conservative; thus a ''failed'' waste package container with multiple perforations may still be an important barrier to radionuclide release

  9. BUSINESS DEVELOPMENT, FOREIGN DIRECT INVESTMENT AND INTERNATIONAL TRADE: A policy and economic comparative analysis for Canada

    Directory of Open Access Journals (Sweden)

    Isabel Husid

    2015-01-01

    Full Text Available The present work aims to achieve an overall view of Foreign Direct Investment and International Trade in Canada, analyzing both the current situation and the actions and policies being implemented by several provinces to promote this subject. This study will be valuable to companies and governments to understand what has been done and to support strategic planning to invest and trade with Canada, especially for the Brazilian market.

  10. Democratic cultural policy : democratic forms and policy consequences

    OpenAIRE

    Gray, Clive

    2012-01-01

    The forms that are adopted to give practical meaning to democracy are assessed to identify what their implications are for the production of public policies in general and cultural policies in particular. A comparison of direct, representative, democratic elitist and deliberative versions of democracy identifies clear differences between them in terms of policy form and democratic practice. Further elaboration of these differences and their consequences are identified as areas for further res...

  11. Dynamics of rapid dopamine release in the nucleus accumbens during goal-directed behaviors for cocaine versus natural rewards.

    Science.gov (United States)

    Cameron, Courtney M; Wightman, R Mark; Carelli, Regina M

    2014-11-01

    Electrophysiological studies show that distinct subsets of nucleus accumbens (NAc) neurons differentially encode information about goal-directed behaviors for intravenous cocaine versus natural (food/water) rewards. Further, NAc rapid dopamine signaling occurs on a timescale similar to phasic cell firing during cocaine and natural reward-seeking behaviors. However, it is not known whether dopamine signaling is reinforcer specific (i.e., is released during responding for only one type of reinforcer) within discrete NAc locations, similar to neural firing dynamics. Here, fast-scan cyclic voltammetry (FSCV) was used to measure rapid dopamine release during multiple schedules involving sucrose reward and cocaine self-administration (n = 8 rats) and, in a separate group of rats (n = 6), during a sucrose/food multiple schedule. During the sucrose/cocaine multiple schedule, dopamine increased within seconds of operant responding for both reinforcers. Although dopamine release was not reinforcer specific, more subtle differences were observed in peak dopamine concentration [DA] across reinforcer conditions. Specifically, peak [DA] was higher during the first phase of the multiple schedule, regardless of reinforcer type. Further, the time to reach peak [DA] was delayed during cocaine-responding compared to sucrose. During the sucrose/food multiple schedule, increases in dopamine release were also observed relative to operant responding for both natural rewards. However, peak [DA] was higher relative to responding for sucrose than food, regardless of reinforcer order. Overall, the results reveal the dynamics of rapid dopamine signaling in discrete locations in the NAc across reward conditions, and provide novel insight into the functional role of this system in reward-seeking behaviors. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. 19 CFR 12.114 - Release or refusal of delivery.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Release or refusal of delivery. 12.114 Section 12... delivery. If the completed Notice of Arrival directs the port director to release the shipment of... directs the port director to refuse delivery of the shipment, the shipment shall be refused delivery and...

  13. The New Cannabis Policy Taxonomy on APIS: Making Sense of the Cannabis Policy Universe.

    Science.gov (United States)

    Klitzner, Michael D; Thomas, Sue; Schuler, Jonathan; Hilton, Michael; Mosher, James

    2017-06-01

    The National Institute on Alcohol Abuse and Alcoholism's Alcohol Policy Information System (APIS) is, for the first time, adding legal data pertaining to recreational cannabis use to its current offerings on alcohol policy. Now that Colorado, Washington, Oregon, Alaska, and the District of Columbia have legalized aspects of recreational cannabis, and more states are considering it, there is an urgency to provide high-quality, multi-dimensional legal data to the public health community. This article introduces the Cannabis Policy Taxonomy recently posted on APIS, and explores its theoretical and empirical contributions to the substance abuse literature and its potential for use in policy research. We also present results of interviews with public health experts in alcohol and cannabis policy, which sought to determine the most important variables to address in the initial release of cannabis policy data. From this process, we found that pricing controls emerged as the variable singled out by the largest number of experts. This analysis points to a host of vital policies that are of increasing importance to public health policy scholars and their current and future research.

  14. Changing U.S. Ocean Policy Can Set a New Direction for Marine Resource Management

    Directory of Open Access Journals (Sweden)

    Andrew A. Rosenberg

    2009-12-01

    Full Text Available A central concept in a new direction for ocean policy in the United States is ecosystem-based management, that is, implementation of management integrated across sectors of human activity to achieve the common goal of conserving the structure and function of marine ecosystems to provide a full suite of ecosystem services. Fisheries are a critical sector of ocean activity that impacts these ecosystems, and fishery management is in urgent need of reform to perform better from a conservation perspective. Here, I suggest some specific changes in perspective for fishery management as part of an overall ecosystem-based approach.

  15. Why are common quality and development policies needed?

    International Nuclear Information System (INIS)

    Alandes, M; Abad, A; Dini, L; Guerrero, P

    2012-01-01

    The EMI project is based on the collaboration of four major middleware projects in Europe, all already developing middleware products and having their pre-existing strategies for developing, releasing and controlling their software artefacts. In total, the EMI project is made up of about thirty development individual teams, called “Product Teams” in EMI. A Product Team is responsible for the entire lifecycle of specific products or small groups of tightly coupled products, including the development of test-suites to be peer reviewed within the overall certification process. The Quality Assurance in EMI (European Middleware Initiative), as requested by the grid infrastructures and the EU funding agency, must support the teams in providing uniform releases and interoperable middleware distributions, with a common degree of verification and validation of the software and with metrics and objective criteria to compare product quality and evolution over time. In order to achieve these goals, the QA team in EMI has defined and now it monitors the development work and release with a set of comprehensive policies covering all aspects of a software project such as packaging, configuration, documentation, certification, release management and testing. This contribution will present with practical and useful examples the achievements, problems encountered and lessons learned in the definition, implementation and review of Quality Assurance and Development policies. It also describes how these policies have been implemented in the EMI project including the benefits and difficulties encountered by the developers in the project. The main value of this contribution is that all the policies explained are not depending on EMI or grid environments and can be used by any software project.

  16. Carbon Leakage Revisited : Unilateral Climate Policy with Directed Technical Change

    NARCIS (Netherlands)

    Di Maria, C.; van der Werf, E.H.

    2005-01-01

    The increase in carbondioxide emissions by some countries in reaction to an emission reduction by countries with climate policy (carbon leakage) is seen as a serious threat to unilateral climate policy.Using a two-country model where only one of the countries enforces an exogenous cap on emissions,

  17. Development of DOE complexwide authorized release protocols for radioactive scrap metals

    International Nuclear Information System (INIS)

    Chen, S. Y.

    1998-01-01

    Within the next few decades, several hundred thousand tons of metal are expected to be removed from nuclear facilities across the U.S. Department of Energy (DOE) complex as a result of decontamination and decommissioning (D and D) activities. These materials, together with large quantities of tools, equipment, and other items that are commonly recovered from site cleanup or D and D activities, constitute non-real properties that warrant consideration for reuse or recycle, as permitted and practiced under the current DOE policy. The provisions for supporting this policy are contained in the Draft Handbook for Controlling Release for Reuse or Recycle of Property Containing Residual Radioactive Material published by DOE in 1997 and distributed to DOE field offices for interim use and implementation. The authorized release of such property is intended to permit its beneficial use across the entire DOE complex. The objective of this study is to develop readily usable computer-based release protocols to facilitate implementation of the Handbook in evaluating the scrap metals for reuse and recycle. The protocols provide DOE with an effective oversight tool for managing release activities

  18. LTER network data access policy revision: report and recommendations.

    Science.gov (United States)

    James Brunt; Peter McCartney; Stuart Gage; Don. Henshaw

    2004-01-01

    This document is a report on work carried out to update the LTER Network Data Access Policy. The current LTER Network Data Access Policy, approved by the coordinating committee in 1997, has been in use since 1990. An analysis of the current policies related to the release, access, and use of LTER data has been undertaken by a sub-committee of the LTER Network...

  19. Pollutant Release and Transfer Register

    International Nuclear Information System (INIS)

    2008-01-01

    Since 1974 a number of organisations have been working closely together in this pollutant register (PRTR) project to collect and formally establish the yearly releases of pollutants to air, water and soil in the Netherlands. Results of this project serve to underpin the national environmental policy. Data is in this way also provided for the many environmental reports to international organisations such as the European Union and the United Nations, e.g. the National Inventory Report for the Kyoto Protocol. This website shows the yearly releases (emissions) of the most important pollutants in the Netherlands. You can explore the emission data through various channels, such as maps, graphs and tables. But you can also download all the details into your own database. The data shown in this website is updated 2 to 3 times a year. The current release shows emissions for 1990, 1995, 2000, 2004, 2005 and 2006 The 2006 emissions are preliminary data and not yet shown in the maps. We expect to add an extra year in August 2008 [nl

  20. Reduction of prostate intrafraction motion using gas-release rectal balloons

    International Nuclear Information System (INIS)

    Su Zhong; Zhao Tianyu; Li Zuofeng; Hoppe, Brad; Henderson, Randy; Mendenhall, William; Nichols, R. Charles; Marcus, Robert; Mendenhall, Nancy

    2012-01-01

    Purpose: To analyze prostate intrafraction motion using both non-gas-release (NGR) and gas-release (GR) rectal balloons and to evaluate the ability of GR rectal balloons to reduce prostate intrafraction motion. Methods: Twenty-nine patients with NGR rectal balloons and 29 patients with GR balloons were randomly selected from prostate patients treated with proton therapy at University of Florida Proton Therapy Institute (Jacksonville, FL). Their pretreatment and post-treatment orthogonal radiographs were analyzed, and both pretreatment setup residual error and intrafraction-motion data were obtained. Population histograms of intrafraction motion were plotted for both types of balloons. Population planning target-volume (PTV) margins were calculated with the van Herk formula of 2.5Σ+ 0.7σ to account for setup residual errors and intrafraction motion errors. Results: Pretreatment and post-treatment radiographs indicated that the use of gas-release rectal balloons reduced prostate intrafraction motion along superior–inferior (SI) and anterior–posterior (AP) directions. Similar patient setup residual errors were exhibited for both types of balloons. Gas-release rectal balloons resulted in PTV margin reductions from 3.9 to 2.8 mm in the SI direction, 3.1 to 1.8 mm in the AP direction, and an increase from 1.9 to 2.1 mm in the left–right direction. Conclusions: Prostate intrafraction motion is an important uncertainty source in radiotherapy after image-guided patient setup with online corrections. Compared to non-gas-release rectal balloons, gas-release balloons can reduce prostate intrafraction motion in the SI and AP directions caused by gas buildup.

  1. Reduction of prostate intrafraction motion using gas-release rectal balloons

    Energy Technology Data Exchange (ETDEWEB)

    Su Zhong; Zhao Tianyu; Li Zuofeng; Hoppe, Brad; Henderson, Randy; Mendenhall, William; Nichols, R. Charles; Marcus, Robert; Mendenhall, Nancy [Department of Radiation Oncology, University of Florida Proton Therapy Institute, Jacksonville, Florida 32206 (United States)

    2012-10-15

    Purpose: To analyze prostate intrafraction motion using both non-gas-release (NGR) and gas-release (GR) rectal balloons and to evaluate the ability of GR rectal balloons to reduce prostate intrafraction motion. Methods: Twenty-nine patients with NGR rectal balloons and 29 patients with GR balloons were randomly selected from prostate patients treated with proton therapy at University of Florida Proton Therapy Institute (Jacksonville, FL). Their pretreatment and post-treatment orthogonal radiographs were analyzed, and both pretreatment setup residual error and intrafraction-motion data were obtained. Population histograms of intrafraction motion were plotted for both types of balloons. Population planning target-volume (PTV) margins were calculated with the van Herk formula of 2.5{Sigma}+ 0.7{sigma} to account for setup residual errors and intrafraction motion errors. Results: Pretreatment and post-treatment radiographs indicated that the use of gas-release rectal balloons reduced prostate intrafraction motion along superior-inferior (SI) and anterior-posterior (AP) directions. Similar patient setup residual errors were exhibited for both types of balloons. Gas-release rectal balloons resulted in PTV margin reductions from 3.9 to 2.8 mm in the SI direction, 3.1 to 1.8 mm in the AP direction, and an increase from 1.9 to 2.1 mm in the left-right direction. Conclusions: Prostate intrafraction motion is an important uncertainty source in radiotherapy after image-guided patient setup with online corrections. Compared to non-gas-release rectal balloons, gas-release balloons can reduce prostate intrafraction motion in the SI and AP directions caused by gas buildup.

  2. An inter-disciplinary assessment of the implementation of a European environmental policy. The municipal waste incineration directive (89/429/CEE); Une evaluation interdisciplinaire de la mise en oeuvre d'une politique environnementale europeenne. La directive relative aux incinerateurs des dechets municipaux (89/429/CEE)

    Energy Technology Data Exchange (ETDEWEB)

    Schucht, S

    2005-12-15

    In its communications, the European Commission regularly points to a shortfall between the objectives defined by European environmental Directives and their implementation in the Member States. While from the legal perspective of this institution, such implementation gaps are undesirable, from a normative economic point of view they can in certain cases be justified by efficiency considerations, provided the initial policy is subject to inefficiencies. This thesis analyses the implementation of European environmental Directives. More specifically, it studies in detail the efficiency of the Council Directive of 21 June 1989 on the reduction of air pollution from existing municipal waste-incineration plants (89/429/EEC) and the cost-effectiveness of its implementation in France, Germany, the Netherlands and the United Kingdom. One of the guiding questions is whether possible inefficiencies in this policy may have justified an implementation deficit from an economic point of view and whether implementation has (partly) restored the efficiency of the policy. A review of frequent origins of implementation gaps in European environmental policy suggested by political science based literature highlights two features of European policy making: the separation of competences in policy making and implementation which potentially results in policy makers neglecting implementation issues during the policy design phase; and the heterogeneity of national contexts which arc difficult to accommodate by one European policy. Both are important with respect to implementation costs, as one lesson of economic theory is that minimising the overall costs of a regulation requires to properly take into account local situations. Studying the economic efficiency of the municipal waste incineration Directive with respect to its allocation of tasks between the European and the Member State levels and with respect to the cost-effectiveness of its standard differentiation suggests that this policy

  3. An inter-disciplinary assessment of the implementation of a European environmental policy. The municipal waste incineration directive (89/429/CEE); Une evaluation interdisciplinaire de la mise en oeuvre d'une politique environnementale europeenne. La directive relative aux incinerateurs des dechets municipaux (89/429/CEE)

    Energy Technology Data Exchange (ETDEWEB)

    Schucht, S.

    2005-12-15

    In its communications, the European Commission regularly points to a shortfall between the objectives defined by European environmental Directives and their implementation in the Member States. While from the legal perspective of this institution, such implementation gaps are undesirable, from a normative economic point of view they can in certain cases be justified by efficiency considerations, provided the initial policy is subject to inefficiencies. This thesis analyses the implementation of European environmental Directives. More specifically, it studies in detail the efficiency of the Council Directive of 21 June 1989 on the reduction of air pollution from existing municipal waste-incineration plants (89/429/EEC) and the cost-effectiveness of its implementation in France, Germany, the Netherlands and the United Kingdom. One of the guiding questions is whether possible inefficiencies in this policy may have justified an implementation deficit from an economic point of view and whether implementation has (partly) restored the efficiency of the policy. A review of frequent origins of implementation gaps in European environmental policy suggested by political science based literature highlights two features of European policy making: the separation of competences in policy making and implementation which potentially results in policy makers neglecting implementation issues during the policy design phase; and the heterogeneity of national contexts which arc difficult to accommodate by one European policy. Both are important with respect to implementation costs, as one lesson of economic theory is that minimising the overall costs of a regulation requires to properly take into account local situations. Studying the economic efficiency of the municipal waste incineration Directive with respect to its allocation of tasks between the European and the Member State levels and with respect to the cost-effectiveness of its standard differentiation suggests that this policy

  4. Global mHealth policy arena: status check and future directions.

    Science.gov (United States)

    Malvey, Donna M; Slovensky, Donna J

    2017-01-01

    In this review, we examine an important piece of the mHealth puzzle that has received scant attention-health policy. The question is whether health policy ultimately will serve to unite nations in advancing global mHealth or, as Mars and Scott suggested in 2010, keep nations isolated and ultimately making their policy decisions in "eHealth silos". Such a non-collaborative approach seriously hampers the potential for using mobile health technologies to deliver health care across borders, assuring individuals access to affordable, convenient, and quality healthcare in underserved regions. From a global perspective, mHealth policy review is difficult as some important policies may be subsumed in comprehensive planning and strategy documents. Political, environmental, economic, organizational, and technology disparities across nations represent a significant impediment to developing mHealth products and services that can be deployed globally. To date, there is modest evidence that such challenges are being addressed. Even though payers can encourage adoption of mHealth with financial incentives for use, it appears that payment or reimbursement tends to be a roadblock for almost all nations, whether they are emerging or developed. If payment for mHealth services is not guaranteed, business models will not be sustainable and providers will have fewer opportunities for scalability. Furthermore, because mHealth policies typically are subject to some type of government scrutiny and oversight, many product developers and entrepreneurs may turn elsewhere for their investments. Global resource scarcity also challenges optimal mHealth deployment, and governments seek to ensure improved population health outcomes as return on their mHealth investments. Unfortunately, such justification is difficult as evaluation methods simply have not kept pace with mHealth technology capability. Requisite measurement tools are sorely lacking when it comes to evaluating efficacy of m

  5. Single Policy Study

    DEFF Research Database (Denmark)

    Kronsell, Annica; Manners, Ian James

    2015-01-01

    Single policy studies are the most common form of European Union (EU) research. Single policy studies are widely used to understand the role of the EU in a wide variety of sectors, together with their development over time, and often offer public policy prescriptions. This chapter discusses...... the relevance of single policy studies in EU research and give examples of how such research can be designed and carried out. The chapter reviews three examples of single policy studies using different methods based on EU environmental policy, the EU biofuels directive, and the EU Common Security and Defence...... Policy (CSDP). The examples are illustrative of how single policy studies can be designed to use different approaches in the analysis: multiple streams approach to policy-making; a comparative hypothesis testing; and feminist institutional theory....

  6. Can the Nigerian biofuel policy and incentives (2007) transform Nigeria into a biofuel economy?

    International Nuclear Information System (INIS)

    Ohimain, Elijah I.

    2013-01-01

    Nigeria's economy is largely dependent on petroleum, yet the country is suffering from fuel supply shortages. In response to the transportation fuel supply difficulties in Nigeria, the country released the Nigerian Biofuel Policy and Incentives in 2007 to create favorable investment climate for the entrance of Nigeria into the biofuel sector. The paper assessed the progress made thus far by Nigeria, 4 years after the Nigerian biofuel was released in an attempt to answer the question whether the policy is adequate to transform Nigeria into a biofuel economy. The study found that little progress has been made, which includes commencement of the construction of 20 bioethanol factories, installation of biofuel handling facilities at two depots (Mosimi and Atlas Cove), and selection of retail outlets for biofuel/conventional fuel mix. The site construction of the announced biofuel projects is now slow and other progress is marginal. We therefore conclude that the Nigerian biofuel policy is unlikely to transform Nigeria into a biofuel economy unless the Government revert and refocus on biofuel and include additional financial incentives such as grants and subsidy to complement the tax waivers (income, import duty, VAT), loans, and insurance cover contained in the policy. - Highlights: ► Nigeria's economy is dependent on petroleum, yet the country is suffering from fuel shortages. ► The Nigerian Biofuel Policy and Incentives was released in 2007. ► Little progress has been made since the policy was released 4 years ago. ► Hence, the policy is unlikely to transform Nigeria into a biofuel economy

  7. Development and analysis of security policies in security enhanced Android

    OpenAIRE

    Rimando, Ryan A.

    2012-01-01

    Approved for public release; distribution is unlimited. This thesis examines Security Enhanced Android. Both its policy and its additional security features are explored. The policy is examined in depth, providing a better understanding of the security provided by SE Android. We analyze the default SE Android policy. We identify a potential weakness and change the policy to facilitate control over communication channels. A proof-of-concept set of applications is developed to demonstrate ho...

  8. Sensitivity of the engineered barrier system (EBS) release rate to alternative conceptual models of advective release from waste packages under dripping fractures

    International Nuclear Information System (INIS)

    Lee, J.H.; Atkins, J.E.; McNeish, J.A.; Vallikat, V.

    1996-01-01

    Simulations were conducted to analyze the sensitivity of the engineered barrier system (EBS) release rate to alternative conceptual models of the advective release from waste packages under dripping fractures. The first conceptual model assumed that dripping water directly contacts the waste form inside the 'failed' waste package, and radionuclides are released from the EBS by advection. The second conceptual model assumed that dripping water is diverted around the 'failed' waste package (because of the presence of corrosion products plugging the perforations) and dripping water is prevented from directly contacting the waste form. In the second model, radionuclides were assumed to transport through the perforations by diffusion, and, once outside the waste package, to be released from the EBS by advection. The second model was to incorporate more realism into the EBS release calculations. For the case with the second EBS release model, most radionuclides had significantly lower peak EBS release rates (from at least one to several orders of magnitude) than with the first EBS release model. The impacts of the alternative EBS release models were greater for the radionuclides with a low solubility (or solubility-limited radionuclides) than for the radionuclides with a high solubility (or waste form dissolution-limited radionuclides). The analyses indicated that the EBS release model representing advection through a 'failed' waste package (the first EBS release model) may be too conservative in predicting the EBS performance. One major implication from this sensitivity study was that a 'failed' waste package container with multiple perforations may still be able to perform effectively as an important barrier to radionuclide release. (author)

  9. Tracing policy movements: methods for studying learning and policy circulation

    OpenAIRE

    Wood, Astrid

    2016-01-01

    Policy flows are not quantifiable and calculating processes but part of the uneven movement of ideas and experiences that involves power and personalities. Processes of learning and policy circulation have thus proven difficult to study especially as the exchanges taking place between actors and localities rarely lead directly to uptake. This paper outlines a conceptual and methodological framework for conducting policy mobilities research by attending to the plethora of ordinary practices – ...

  10. Directions and deviations in the Brazilian nuclear policy

    International Nuclear Information System (INIS)

    Leal, M.C.

    1982-01-01

    The emergence of the Brazilian nuclear policy as a subject of interest to the Brazilian society, the conflicts characterizing its formulation and implementation between 1945 and 1958 and the political criteria for executing a Brazilian nuclear program are presented. (M.C.K.) [pt

  11. Developing radioactive waste management policy

    International Nuclear Information System (INIS)

    Gichana, Z.

    2012-04-01

    A policy for radioactive waste management with defined goals and requirements is needed as a basis for the preparation of legislation, review or revision of related legislation and to define roles and responsibilities for ensuring the safe management of radioactive waste. A well defined policy and associated strategies are useful in promoting consistency of emphasis and direction within all of the sectors involved in radioactive waste management. The absence of policy and strategy can lead to confusion or lack of coordination and direction. A policy and/or strategy may sometimes be needed to prevent inaction on a particular waste management issue or to resolve an impasse. (author)

  12. Fracture patterns and the energy release rate of phosphorene.

    Science.gov (United States)

    Liu, Ning; Hong, Jiawang; Pidaparti, Ramana; Wang, Xianqiao

    2016-03-14

    Phosphorene, also known as monolayer black phosphorus, has been enjoying popularity in electronic devices due to its superior electrical properties. However, it's relatively low Young's modulus, low fracture strength and susceptibility to structural failure have limited its application in mechanical devices. Therefore, in order to design more mechanically reliable devices that utilize phosphorene, it is necessary to explore the fracture patterns and energy release rate of phosphorene. In this study, molecular dynamics simulations are performed to investigate phosphorene's fracture mechanism. The results indicate that fracture under uniaxial tension along the armchair direction is attributed to a break in the interlayer bond angles, while failure in the zigzag direction is triggered by the break in both intra-layer angles and bonds. Furthermore, we developed a modified Griffith criterion to analyze the energy release rate of phosphorene and its dependence on the strain rates and orientations of cracks. Simulation results indicate that phosphorene's energy release rate remains almost unchanged in the armchair direction while it fluctuates intensively in the zigzag direction. Additionally, the strain rate was found to play a negligible role in the energy release rate. The geometrical factor α in the Griffith's criterion is almost constant when the crack orientation is smaller than 45 degree, regardless of the crack orientation and loading direction. Overall, these findings provide helpful insights into the mechanical properties and failure behavior of phosphorene.

  13. Main directions and priorities of Ukraine state migration policy in the context of its european integration changes

    Directory of Open Access Journals (Sweden)

    К.V. Shymanska

    2016-09-01

    Full Text Available The exceptional socio-economic importance of migration and its significant impact on the living standards and welfare of the population, labor market, ethnic and religious profile of Ukrainians, cultural and educational environment and migration activation social context cause the raising of the relevance of the research issues on international migration. This article is devoted to the study of existing approaches to identification of main directions and priorities of state migration policy for eliminating of external migration negative effects in Ukraine, ensuring an adequate level of social and economic protection of people and national security of Ukraine. The article considers the current problems of Ukraine's migration policy formation, characterizes the main priorities of Ukraine's migration policy according to its basic component, and describes the tendencies of migration processes in Ukraine and over the world. It is determined that the cooperation between Ukraine and the EU in the case of migratory flow regulating will have a number of advantages including the reduction of illegal migration, preservation of the professional level of Ukrainian migrants and receiving work experience abroad, strengthening their social protection and reduction of illegal employed migrants.

  14. The EU sustainable energy policy indicators framework.

    Science.gov (United States)

    Streimikiene, Dalia; Sivickas, Gintautas

    2008-11-01

    The article deals with indicators framework to monitor implementation of the main EU (European Union) directives and other policy documents targeting sustainable energy development. The main EU directives which have impact on sustainable energy development are directives promoting energy efficiency and use of renewable energy sources, directives implementing greenhouse gas mitigation and atmospheric pollution reduction policies and other policy documents and strategies targeting energy sector. Promotion of use of renewable energy sources and energy efficiency improvements are among priorities of EU energy policy because the use of renewable energy sources and energy efficiency improvements has positive impact on energy security and climate change mitigation. The framework of indicators can be developed to establish the main targets set by EU energy and environmental policies allowing to connect indicators via chain of mutual impacts and to define policies and measures necessary to achieve established targets based on assessment of their impact on the targeted indicators representing sustainable energy development aims. The article discusses the application of indicators framework for EU sustainable energy policy analysis and presents the case study of this policy tool application for Baltic States. The article also discusses the use of biomass in Baltic States and future considerations in this field.

  15. CSchema: A Downgrading Policy Language for XML Access Control

    Institute of Scientific and Technical Information of China (English)

    Dong-Xi Liu

    2007-01-01

    The problem of regulating access to XML documents has attracted much attention from both academic and industry communities.In existing approaches, the XML elements specified by access policies are either accessible or inac-cessible according to their sensitivity.However, in some cases, the original XML elements are sensitive and inaccessible, but after being processed in some appropriate ways, the results become insensitive and thus accessible.This paper proposes a policy language to accommodate such cases, which can express the downgrading operations on sensitive data in XML documents through explicit calculations on them.The proposed policy language is called calculation-embedded schema (CSchema), which extends the ordinary schema languages with protection type for protecting sensitive data and specifying downgrading operations.CSchema language has a type system to guarantee the type correctness of the embedded calcula-tion expressions and moreover this type system also generates a security view after type checking a CSchema policy.Access policies specified by CSchema are enforced by a validation procedure, which produces the released documents containing only the accessible data by validating the protected documents against CSchema policies.These released documents are then ready tobe accessed by, for instance, XML query engines.By incorporating this validation procedure, other XML processing technologies can use CSchema as the access control module.

  16. Country policy profile - Poland. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Poland is 15%. Poland promotes renewable electricity through a quota system, tax relief and subsidies, as well as loans. There are three subsidy models and a loan scheme, which support heat generated from renewable energy sources. In dimension to transport renewable energy is promoted primarily by bio-fuels. The Republic of Poland established two programmes for renewable energy plants: a training programme, which is dedicated to installers in RES sector and certification system pertaining solar thermal installations. This report monitors the policy changes after the release of the 2013 Progress Report for Poland and was regularly updated (updated until December 2015)

  17. Toward a better union: improving the effectiveness of foreign policies

    OpenAIRE

    Bradshaw, Daniel J.

    2014-01-01

    Approved for public release; distribution is unlimited A fundamental characteristic of state-state interaction in a globalized system is the explicitness with which states communicate their foreign policies to each other. In order to understand the role and the importance of foreign policy explicitness in the global foreign policy system, I first created a simple mesh model of the actors and institutions that form the U.S. foreign policy system. By optimizing this model with various system...

  18. [The Catalan Patient Council: the direct voice of the patient in health policies in Catalonia].

    Science.gov (United States)

    Vallès Navarro, Roser; Costa Vilar, Núria; Davins Miralles, Josep; Garcia Cirera, Montserrat; Hernando Ortega, Maria Rosario; Iniesta Blasco, Cristina

    2015-11-01

    The transition from a more paternalistic model of care focused on the disease and on the medical professional's authority towards a more participatory model centered on the rights and duties of informed patients represents a significant change in public health policy. One of the most widespread methods of social participation in Catalonia today is the tendency to form associations around a particular disease. This kind of organizational participation is a pioneering tool in the debate around public health policy. The Government of the Generalitat de Catalunya undertook to promote the Strategic Plan of patient participation within the public health system. The Department of Health created the Patient Advisory Council of Catalonia (CCPC, as per the acronym in Catalan). This initiative constitutes a permanent consultative and participatory body for patient representatives in the Catalan healthcare system. The CCPC was set up with a solid determination to place the patient at the centre of the healthcare system, including them in the decision-making processes which directly affect them. This patient participation plan has defined and developed 8 different lines approved by the government, with consensus approval between regional government and the organisations. The CCPC has proven itself to be an effective tool for fostering active patient participation in health policy and its relationship with the system has evolved from that of a monologue to becoming the mechanism for dialogue it is today. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

  19. Orchestrating Policy Ideas: Philanthropies and Think Tanks in US Education Policy Advocacy Networks

    Science.gov (United States)

    Lubienski, Christopher; Brewer, T. Jameson; La Londe, Priya Goel

    2016-01-01

    While think tanks are a global phenomenon, their role in shaping US policy offers an instructive example of think tank influence on policymaking due to the immensity of resources directed towards those ends, with education policy serving as a prime example. Focusing on a distinct set of "incentivist" education policies, this analysis…

  20. Dynamic water allocation policies improve the global efficiency of storage systems

    Science.gov (United States)

    Niayifar, Amin; Perona, Paolo

    2017-06-01

    Water impoundment by dams strongly affects the river natural flow regime, its attributes and the related ecosystem biodiversity. Fostering the sustainability of water uses e.g., hydropower systems thus implies searching for innovative operational policies able to generate Dynamic Environmental Flows (DEF) that mimic natural flow variability. The objective of this study is to propose a Direct Policy Search (DPS) framework based on defining dynamic flow release rules to improve the global efficiency of storage systems. The water allocation policies proposed for dammed systems are an extension of previously developed flow redistribution rules for small hydropower plants by Razurel et al. (2016).The mathematical form of the Fermi-Dirac statistical distribution applied to lake equations for the stored water in the dam is used to formulate non-proportional redistribution rules that partition the flow for energy production and environmental use. While energy production is computed from technical data, riverine ecological benefits associated with DEF are computed by integrating the Weighted Usable Area (WUA) for fishes with Richter's hydrological indicators. Then, multiobjective evolutionary algorithms (MOEAs) are applied to build ecological versus economic efficiency plot and locate its (Pareto) frontier. This study benchmarks two MOEAs (NSGA II and Borg MOEA) and compares their efficiency in terms of the quality of Pareto's frontier and computational cost. A detailed analysis of dam characteristics is performed to examine their impact on the global system efficiency and choice of the best redistribution rule. Finally, it is found that non-proportional flow releases can statistically improve the global efficiency, specifically the ecological one, of the hydropower system when compared to constant minimal flows.

  1. Integrated Hatchery Operations Team: Policies and Procedures for Columbia Basin Anadromous Salmonid Hatcheries, 1994 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Integrated Hatchery Operations Team (Northwest Power Planning Council, Portland, OR)

    1995-01-01

    This document outlines regional policies and procedures for hatchery operations in the Columbia River Basin. The purpose of these policies is to provide regional guidelines by which all anadromous fish hatcheries will be operated. These policies will be adopted by the fisheries co-managers, and will provide guidance to operate hatcheries in an efficient and biologically sound manner. The hatchery policies presented in this manual are not intended to establish production priorities. Rather, the intent is to guide hatchery operations once production numbers are established. Hatchery operations discussed in this report include broodstock collection, spawning, incubation of eggs, fish rearing and feeding, fish release, equipment maintenance and operations, and personnel training. Decisions regarding production priorities must be provided by fishery managers through a comprehensive plan that addresses both natural and hatchery fish production. The Integrated Hatchery Operations Team is a multi-agency group called for by the Northwest Power Planning Council. This team was directed to develop new basinwide policies for managing and operating all existing and future anadromous fish hatcheries in the Columbia River Basin. The parties pledge to confer with each other and to use their authorities and resources to accomplish these mutually acceptable hatchery practices.

  2. The challenge of multilingualism: in response to the language policy ...

    African Journals Online (AJOL)

    This article investigates the requirements of the newly released Language Policy for Higher Education and provides guidelines for an educational approach that would support multilingual, higher education. In a nutshell, this policy challenges higher education institutions to provide in the linguistic needs of the new, more ...

  3. The use of a policy dialogue to facilitate evidence-informed policy development for improved access to care: the case of the Winnipeg Central Intake Service (WCIS).

    Science.gov (United States)

    Damani, Zaheed; MacKean, Gail; Bohm, Eric; DeMone, Brie; Wright, Brock; Noseworthy, Tom; Holroyd-Leduc, Jayna; Marshall, Deborah A

    2016-10-18

    Policy dialogues are critical for developing responsive, effective, sustainable, evidence-informed policy. Our multidisciplinary team, including researchers, physicians and senior decision-makers, comprehensively evaluated The Winnipeg Central Intake Service, a single-entry model in Winnipeg, Manitoba, to improve patient access to hip/knee replacement surgery. We used the evaluation findings to develop five evidence-informed policy directions to help improve access to scheduled clinical services across Manitoba. Using guiding principles of public participation processes, we hosted a policy roundtable meeting to engage stakeholders and use their input to refine the policy directions. Here, we report on the use and input of a policy roundtable meeting and its role in contributing to the development of evidence-informed policy. Our evidence-informed policy directions focused on formal measurement/monitoring of quality, central intake as a preferred model for service delivery, provincial scope, transparent processes/performance indicators, and patient choice of provider. We held a policy roundtable meeting and used outcomes of facilitated discussions to refine these directions. Individuals from our team and six stakeholder groups across Manitoba participated (n = 44), including patients, family physicians, orthopaedic surgeons, surgical office assistants, Winnipeg Central Intake team, and administrators/managers. We developed evaluation forms to assess the meeting process, and collected decision-maker partners' perspectives on the value of the policy roundtable meeting and use of policy directions to improve access to scheduled clinical services after the meeting, and again 15 months later. We analyzed roundtable and evaluation data using thematic analysis to identify key themes. Four key findings emerged. First, participants supported all policy directions, with revisions and key implementation considerations identified. Second, participants felt the policy roundtable

  4. Direct releases to the surface and associated complementary cumulative distribution functions in the 1996 performance assessment for the Waste Isolation Pilot Plant: cuttings, cavings and spallings

    International Nuclear Information System (INIS)

    Berglund, J.W.; Garner, J.W.; Helton, J.C.; Johnson, J.D.; Smith, L.N.

    2000-01-01

    The following topics related to the treatment of cuttings, cavings and spallings releases to the surface environment in the 1996 performance assessment for the Waste Isolation Pilot Plant (WIPP) are presented: (i) mathematical description of models; (ii) uncertainty and sensitivity analysis results arising from subjective (i.e. epistemic) uncertainty for individual releases; (iii) construction of complementary cumulative distribution functions (CCDFs) arising from stochastic (i.e. aleatory) uncertainty; and (iv) uncertainty and sensitivity analysis results for CCDFs. The presented results indicate that direct releases due to cuttings, cavings and spallings do not constitute a serious threat to the effectiveness of the WIPP as a disposal facility for transuranic waste. Even when the effects of uncertain analysis inputs are taken into account, the CCDFs for cuttings, cavings and spallings releases fall substantially to the left of the boundary line specified in the US Environmental Protection Agency's standard for the geologic disposal of radioactive waste (40 CFR 191, 40 CFR 194)

  5. Direct releases to the surface and associated complementary cumulative distribution functions in the 1996 performance assessment for the Waste Isolation Pilot Plant: Cuttings, cavings and spallings

    International Nuclear Information System (INIS)

    Berglund, J.W.; Garner, J.W.; Helton, Jon Craig; Johnson, J.D.; Smith, L.N.; Anderson, R.P.

    2000-01-01

    The following topics related to the treatment of cuttings, cavings and spallings releases to the surface environment in the 1996 performance assessment for the Waste Isolation Pilot Plant (WIPP) are presented: (1) mathematical description of models. (2) uncertainty and sensitivity analysis results arising from subjective (i.e., epistemic) uncertainty for individual releases, (3) construction of complementary cumulative distribution functions (CCDFs) arising from stochastic (i.e., aleatory) uncertainty, and (4) uncertainty and sensitivity analysis results for CCDFs. The presented results indicate that direct releases due to cuttings, cavings and spallings do not constitute a serious threat to the effectiveness of the WIPP as a disposal facility for transuranic waste. Even when the effects of uncertain analysis inputs are taken into account, the CCDFs for cuttings, cavings and spallings releases fall substantially to the left of the boundary line specified in the US Environmental Protection Agency standard for the geologic disposal of radioactive waste (40 CFR 191, 40 CFR 194)

  6. Wrong directions of the energetic policy; Descaminhos da politica energetica

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Joaquim Francisco

    1997-12-31

    The energetic planning should take an important role in the formulation of the economic and social development policy of any country. This work presents the opinion of the author in relation to this issue in what concerns the Brazilian experience. Several actions considered wrong by the author, which were taken by the government in what concerns energetic policy are presented and their expected consequences in the near future are discussed 6 refs., 1 tab.

  7. Innovations in climate policy: conclusions and new directions

    NARCIS (Netherlands)

    Jordan, A.; Huitema, D.

    2014-01-01

    Academics and practitioners have responded to the gridlock in the international climate-change regime by more actively exploring the ability of individuals and/or groups of states to fill in the associated ‘governance gaps’ by engaging in policy innovation at the level of the nation state, including

  8. Regulatory policy governing cadmium-telluride photovoltaics: A case study contrasting life cycle management with the precautionary principle

    International Nuclear Information System (INIS)

    Sinha, Parikhit; Kriegner, Christopher J.; Schew, William A.; Kaczmar, Swiatoslav W.; Traister, Matthew; Wilson, David J.

    2008-01-01

    Market projections for cadmium-telluride (CdTe) thin-film photovoltaics (PV) are tempered by global environmental policies based on the precautionary principle which restrict electronic products containing cadmium, a known human carcinogen. An alternative to the precautionary principle is life cycle management, which involves manufacturers assuming product stewardship from beginning to end of product life. Both approaches have the aim of minimizing environmental contamination, but attempt to do so in different ways. Restrictions on electronic products containing cadmium by the precautionary principle-based restriction of hazardous substances (RoHS) directive in the European Union and a similar policy in China are presented, relative to their potential impact on CdTe PV. Life cycle environmental risks with respect to potential release of cadmium to the environment are also presented for routine operation of CdTe PV panels, potential catastrophic release of cadmium from a residential fire, and at the end of the product life. There is negligible risk of environmental cadmium contamination during routine operation and insignificant risk during catastrophic exposure events such as fire. At the end of the product life, risks of contamination are minimized by take-back programs that may be paid for by insurance premiums incorporated into the cost of the product. Therefore, policies based on the precautionary principle that could potentially ban the product based on its cadmium content may not be warranted

  9. Regulatory policy governing cadmium-telluride photovoltaics: A case study contrasting life cycle management with the precautionary principle

    Energy Technology Data Exchange (ETDEWEB)

    Sinha, Parikhit; Kriegner, Christopher J.; Schew, William A.; Kaczmar, Swiatoslav W.; Traister, Matthew; Wilson, David J. [O' Brien and Gere, Ecological Sciences, E. 512 Township Line Road, Two Valley Square, Suite 120, Blue Bell, PA 19422 (United States)

    2008-01-15

    Market projections for cadmium-telluride (CdTe) thin-film photovoltaics (PV) are tempered by global environmental policies based on the precautionary principle which restrict electronic products containing cadmium, a known human carcinogen. An alternative to the precautionary principle is life cycle management, which involves manufacturers assuming product stewardship from beginning to end of product life. Both approaches have the aim of minimizing environmental contamination, but attempt to do so in different ways. Restrictions on electronic products containing cadmium by the precautionary principle-based restriction of hazardous substances (RoHS) directive in the European Union and a similar policy in China are presented, relative to their potential impact on CdTe PV. Life cycle environmental risks with respect to potential release of cadmium to the environment are also presented for routine operation of CdTe PV panels, potential catastrophic release of cadmium from a residential fire, and at the end of the product life. There is negligible risk of environmental cadmium contamination during routine operation and insignificant risk during catastrophic exposure events such as fire. At the end of the product life, risks of contamination are minimized by take-back programs that may be paid for by insurance premiums incorporated into the cost of the product. Therefore, policies based on the precautionary principle that could potentially ban the product based on its cadmium content may not be warranted. (author)

  10. Directed International Technological Change and Climate Policy: New Methods for Identifying Robust Policies Under Conditions of Deep Uncertainty

    Science.gov (United States)

    Molina-Perez, Edmundo

    It is widely recognized that international environmental technological change is key to reduce the rapidly rising greenhouse gas emissions of emerging nations. In 2010, the United Nations Framework Convention on Climate Change (UNFCCC) Conference of the Parties (COP) agreed to the creation of the Green Climate Fund (GCF). This new multilateral organization has been created with the collective contributions of COP members, and has been tasked with directing over USD 100 billion per year towards investments that can enhance the development and diffusion of clean energy technologies in both advanced and emerging nations (Helm and Pichler, 2015). The landmark agreement arrived at the COP 21 has reaffirmed the key role that the GCF plays in enabling climate mitigation as it is now necessary to align large scale climate financing efforts with the long-term goals agreed at Paris 2015. This study argues that because of the incomplete understanding of the mechanics of international technological change, the multiplicity of policy options and ultimately the presence of climate and technological change deep uncertainty, climate financing institutions such as the GCF, require new analytical methods for designing long-term robust investment plans. Motivated by these challenges, this dissertation shows that the application of new analytical methods, such as Robust Decision Making (RDM) and Exploratory Modeling (Lempert, Popper and Bankes, 2003) to the study of international technological change and climate policy provides useful insights that can be used for designing a robust architecture of international technological cooperation for climate change mitigation. For this study I developed an exploratory dynamic integrated assessment model (EDIAM) which is used as the scenario generator in a large computational experiment. The scope of the experimental design considers an ample set of climate and technological scenarios. These scenarios combine five sources of uncertainty

  11. Universal approximators for multi-objective direct policy search in water reservoir management problems: a comparative analysis

    Science.gov (United States)

    Giuliani, Matteo; Mason, Emanuele; Castelletti, Andrea; Pianosi, Francesca

    2014-05-01

    The optimal operation of water resources systems is a wide and challenging problem due to non-linearities in the model and the objectives, high dimensional state-control space, and strong uncertainties in the hydroclimatic regimes. The application of classical optimization techniques (e.g., SDP, Q-learning, gradient descent-based algorithms) is strongly limited by the dimensionality of the system and by the presence of multiple, conflicting objectives. This study presents a novel approach which combines Direct Policy Search (DPS) and Multi-Objective Evolutionary Algorithms (MOEAs) to solve high-dimensional state and control space problems involving multiple objectives. DPS, also known as parameterization-simulation-optimization in the water resources literature, is a simulation-based approach where the reservoir operating policy is first parameterized within a given family of functions and, then, the parameters optimized with respect to the objectives of the management problem. The selection of a suitable class of functions to which the operating policy belong to is a key step, as it might restrict the search for the optimal policy to a subspace of the decision space that does not include the optimal solution. In the water reservoir literature, a number of classes have been proposed. However, many of these rules are based largely on empirical or experimental successes and they were designed mostly via simulation and for single-purpose reservoirs. In a multi-objective context similar rules can not easily inferred from the experience and the use of universal function approximators is generally preferred. In this work, we comparatively analyze two among the most common universal approximators: artificial neural networks (ANN) and radial basis functions (RBF) under different problem settings to estimate their scalability and flexibility in dealing with more and more complex problems. The multi-purpose HoaBinh water reservoir in Vietnam, accounting for hydropower

  12. Internet marketing directed at children on food and restaurant websites in two policy environments.

    Science.gov (United States)

    Kent, M Potvin; Dubois, L; Kent, E A; Wanless, A J

    2013-04-01

    Food and beverage marketing has been associated with childhood obesity yet little research has examined the influence of advertising policy on children's exposure to food/beverage marketing on the Internet. The purpose of this study was to assess the influence of Quebec's Consumer Protection Act and the self-regulatory Canadian Children's Food and Beverage Advertising Initiative (CAI) on food manufacturer and restaurant websites in Canada. A content analysis of 147 French and English language food and restaurant websites was undertaken. The presence of child-directed content was assessed and an analysis of marketing features, games and activities, child protection features, and the promotion of healthy lifestyle messages was then examined on those sites with child-directed content. There were statistically no fewer French language websites (n = 22) with child-directed content compared to English language websites (n = 27). There were no statistically significant differences in the number of the various marketing features, or in the average number of marketing features between the English and French websites. There were no fewer CAI websites (n = 14) with child-directed content compared to non-CAI websites (n = 13). The CAI sites had more healthy lifestyle messages and child protection features compared to the non-CAI sites. Systematic surveillance of the Consumer Protection Act in Quebec is recommended. In the rest of Canada, the CAI needs to be significantly expanded or replaced by regulatory measures to adequately protect children from the marketing of foods/beverages high in fat, sugar, and sodium on the Internet. Copyright © 2012 The Obesity Society.

  13. Environmental policy and environment-saving technologies. Economic aspects of policy making under uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Ossokina, I.

    2003-07-01

    It is generally known that natural environment is profoundly influenced by technological change. The direction and the size of this influence are, however, surrounded by uncertainties, which substantially complicate environmental policy making. This dissertation uses game-theoretical models to study policy making under uncertainty about (a) the costs of technological advances in pollution control, (b) the preferences of the policy maker and the voters, and (c) the consequences of policy measures. From a positive point of view the analysis provides explanations for environmental policies in modern democracies. From a normative point of view it gives a number of recommendations to improve environmental policies.

  14. Politics and Policies of Promoting Multilingualism in the European Union

    Science.gov (United States)

    Romaine, Suzanne

    2013-01-01

    This article examines the politics of policies promoting multilingualism in the European Union (EU), specifically in light of the recently released European Union Civil Society Platform on Multilingualism. As the most far-reaching and ambitious policy document issued by the European Commission, the Platform warrants close scrutiny at a significant…

  15. Introduction of direct-to-consumer advertising of prescription drugs in Canada: an opinion survey on regulatory policy.

    Science.gov (United States)

    Mintzes, Barbara; Barer, Morris; Lexchin, Joel; Bassett, Ken L

    2005-06-01

    Canada is strongly influenced by US cross-border direct-to-consumer advertising (DTCA) and has held consultations to discuss introduction of DTCA since 1996. This article describes a survey of Canadian drug policy experts carried out in 2001, during one such legislative review. The survey results are compared to more recent DTCA policy developments. We recruited key informants on pharmaceutical policy to complete a faxed questionnaire that queried their opinions on DTCA information quality, effects on drug and health care use, and regulatory issues. Respondents were asked about the evidence they had used to back their opinions. Analysis was descriptive. Of 79 identified potential participants, 60 (76%) participated, 40% of whom were from federal and provincial government; 3% were private insurers; 18%, 15%, and 8% were from health professional groups, consumer groups, and patient groups, respectively; 8% and 7% were from pharmaceutical and advertising industries, respectively. Opinions were highly polarized on the effects of DTCA on drug and health care use. Advertising and pharmaceutical industry respondents were generally positive, public sector, health professional and consumer groups generally negative. Over 80% believed DTCA leads to higher private and public drug costs and more frequent physician visits. Fewer judged billboards or television to be appropriate media for DTCA than magazines or the Internet, and most believed that children and adolescents should not be targeted. Given the polarization observed within this survey, we examined how DTCA policy has evolved in Canada since 2001. The federal government has legislative authority over DTCA, but bears few of the additional costs potentially incurred through policy change. These fall to the provinces, which provide an eroding patchwork of public coverage for prescription drugs in the face of rapidly increasing costs. No new federal legislation has been tabled since 2001. However, considerable shifts in

  16. EPA Releases Draft Policy to Reduce Animal Testing for Skin Sensitization

    Science.gov (United States)

    The document, Draft Interim Science Policy: Use of Alternative Approaches for Skin Sensitization as a Replacement for Laboratory Animal Testing, describes the science behind the non-animal alternatives that can now be used to identify skin sensitization.

  17. Current Policies and New Directions for Speech-Language Pathology Assistants.

    Science.gov (United States)

    Paul-Brown, Diane; Goldberg, Lynette R

    2001-01-01

    This article provides an overview of current American Speech-Language-Hearing Association (ASHA) policies for the appropriate use and supervision of speech-language pathology assistants with an emphasis on the need to preserve the role of fully qualified speech-language pathologists in the service delivery system. Seven challenging issues surrounding the appropriate use of speech-language pathology assistants are considered. These include registering assistants and approving training programs; membership in ASHA; discrepancies between state requirements and ASHA policies; preparation for serving diverse multicultural, bilingual, and international populations; supervision considerations; funding and reimbursement for assistants; and perspectives on career-ladder/bachelor-level personnel. The formation of a National Leadership Council is proposed to develop a coordinated strategic plan for addressing these controversial and potentially divisive issues related to speech-language pathology assistants. This council would implement strategies for future development in the areas of professional education pertaining to assistant-level supervision, instruction of assistants, communication networks, policy development, research, and the dissemination/promotion of information regarding assistants.

  18. Radiotherapy boost dose-escalation for invasive breast cancer after breast-conserving surgery: 2093 Patients treated with a prospective margin-directed policy

    International Nuclear Information System (INIS)

    Livi, Lorenzo; Meattini, Icro; Franceschini, Davide; Saieva, Calogero; Meacci, Fiammetta; Marrazzo, Livia; Gerlain, Elena; Desideri, Isacco; Scotti, Vieri; Nori, Jacopo; Sanchez, Luis Jose; Orzalesi, Lorenzo; Bonomo, Pierluigi; Greto, Daniela; Bianchi, Simonetta; Biti, Giampaolo

    2013-01-01

    Purpose: To investigate the outcome of invasive early breast cancer patients that underwent breast-conserving surgery and adjuvant radiotherapy (RT), treated with a prospective margin-directed institutional policy for RT boost dose, based on final margins status (FMS). Methods and materials: A total of 2093 patients were treated between 2000 and 2008. 10 Gy boost was prescribed in case of FMS > 5 mm; 16 Gy boost with FMS between 2 and 5 mm; 20 Gy boost in case of FMS 5 mm. At multivariate analysis, higher nuclear grade (p = 0.045), triple negative subtype (p = 0.036) and higher T-stage (p = 0.02) resulted as the independent predictors of LR occurrence. Conclusions: Our experience showed that a margin-directed policy of RT boost dose-escalation seems to reduce the negative impact of FMS on LR, but it is not able to overcome the unfavorable effect of higher nuclear grade, higher T stage and triple negative subtype

  19. Unemployment effects of climate policy

    International Nuclear Information System (INIS)

    Babiker, Mustafa H.; Eckaus, Richard S.

    2007-01-01

    This paper models the unemployment effects of restrictions on greenhouse gas emissions, embodying two of the most significant types of short-term economic imperfections that generate unemployment: sectoral rigidities in labor mobility and sectoral rigidities in wage adjustments. A labor policy is also analyzed that would reduce the direct negative economic effects of the emissions restrictions. The politics of limiting greenhouse gas emissions are often dominated by relatively short-term considerations. Yet the current economic modeling of emissions limitations does not embody economic features that are likely to be particularly important in the short term, in particular, the politically sensitive unemployment rate. Moreover, only a few of these studies also consider policies that would offset the negative direct economic effects of emissions restrictions. For plausible estimates of the parameters, the model shows that, with the labor market imperfections, if there were no offsetting policies, the reductions in GNP in the U.S. in the first 10 years after emissions restrictions were imposed would be as much as 4%. However, if there were two policies, instead of just one: a counteracting labor market policy, as well as the emissions restrictions, the negative direct economic effects could be completely eliminated

  20. Readily releasable pool of synaptic vesicles measured at single synaptic contacts.

    Science.gov (United States)

    Trigo, Federico F; Sakaba, Takeshi; Ogden, David; Marty, Alain

    2012-10-30

    To distinguish between different models of vesicular release in brain synapses, it is necessary to know the number of vesicles of transmitter that can be released immediately at individual synapses by a high-calcium stimulus, the readily releasable pool (RRP). We used direct stimulation by calcium uncaging at identified, single-site inhibitory synapses to investigate the statistics of vesicular release and the size of the RRP. Vesicular release, detected as quantal responses in the postsynaptic neuron, showed an unexpected stochastic variation in the number of quanta from stimulus to stimulus at high intracellular calcium, with a mean of 1.9 per stimulus and a maximum of three or four. The results provide direct measurement of the RRP at single synaptic sites. They are consistent with models in which release proceeds from a small number of vesicle docking sites with an average occupancy around 0.7.

  1. Summary 1998. Releases control and environment monitoring for the CEA Centers

    International Nuclear Information System (INIS)

    1998-01-01

    In the framework of its environmental policy, the CEA aims at reduce as weak as possible, in regards to the technological and economic needs, its activities impacts on the people and the environment. This paper contributes to the public information on the radioactive gaseous and liquid releases during the year 1998. It presents data on the releases and the radioactivity levels around the CEA sites and gathers the associated regulation and monitoring methods. (A.L.B.)

  2. Pressure releasing device for reactor container

    International Nuclear Information System (INIS)

    Takeda, Mika.

    1994-01-01

    In the present invention, dose rate to public caused by radioactive rare gases can be decreased. That is, a reactor container contains a reactor pressure vessel incorporating a reactor core. There are disposed a pressure releasing system for releasing the pressure in the reactor pressure vessel to the outside, and a burning device for burning gases released from the pressure releasing system. An exhaustion pipe is disposed to the pressure releasing system. A burning device is disposed to the exhaustion pipe. It is effective to dispose a ventilation port at a portion of the exhaustion pipe upstream of the burning device. In addition, the burning device may preferably be disposed in a multi-stage in the axial direction of the exhaustion pipe. With such procedures, hydrogen in gases discharged along with the release of the pressure in the container is burned. Buoyancy is caused to the exhaustion gases by heat energy upon burning. Since the exhaustion gases can reach a higher level by the buoyancy, the dose rate due to the rare gases can be reduced. (I.S.)

  3. Environmental policy performance revisited

    DEFF Research Database (Denmark)

    Daugbjerg, Carsten; Sønderskov, Kim Mannemar

    2012-01-01

    . On the basis of the typology, a hypothesis on their ability to expand green markets is generated and tested in a comparative analysis of the performance of organic food policies in Denmark, Sweden, the UK and the US, focusing on their impact on organic consumption. Our analysis demonstrates that cross......Studies of environmental policy performance tend to concentrate on the impact of particular policy institutions or of single policy instruments. However, environmental policies most often consist of a package of policy instruments. Further, these studies pay no or very little attention to policy...... instruments directed at the demand side of the market. Therefore this article develops a policy typology for government intervention aimed at creating green markets. The typology distinguishes between four types of policy based on the balance between the supply-side and demand-side policy instruments...

  4. Co-formation and co-release of genotoxic PAHs, alkyl-PAHs and soot nanoparticles from gasoline direct injection vehicles

    Science.gov (United States)

    Muñoz, Maria; Haag, Regula; Honegger, Peter; Zeyer, Kerstin; Mohn, Joachim; Comte, Pierre; Czerwinski, Jan; Heeb, Norbert V.

    2018-04-01

    Gasoline direct injection (GDI) vehicles quickly replace traditional port-fuel injection (PFI) vehicles in Europe reaching about 50 million vehicles on roads in 2020. GDI vehicles release large numbers of soot nanoparticles similar to conventional diesel vehicles without particle filters. These exhausts will increasingly affect air quality in European cities. We hypothesized that such particles are released together with polycyclic aromatic hydrocarbons (PAHs) formed under the same combustion conditions. Emission data of a fleet of 7 GDI vehicles (1.2-1.8 L) including Euro-3,-4,-5 and -6 technologies revealed substantial particle emissions on average of 2.5 × 1012 particles km-1 in the cold worldwide harmonized light vehicle test cycle (cWLTC), the future European legislative driving cycle. Particle emissions increased 2-3 orders of magnitude during acceleration like CO, indicating that transient driving produces fuel-rich conditions with intense particle formation. For comparison, an Euro-5 diesel vehicle (1.6 L) equipped with a particle filter released 3.9 × 1010 particles km-1 (cWLTC), clearly within the Euro-5/6 limit value of 6.0 × 1011 particles km-1 and 64-fold below the GDI fleet average. PAH and alkyl-PAH emissions of the GDI vehicles also exceeded those of the diesel vehicle. Mean GDI emissions of 2-, 3-, 4-, 5- and 6-ring PAHs in the cWLTC were 240, 44, 5.8, 0.5 and 0.4 μg km-1, those of the diesel vehicle were only 8.8, 7.1, 8.6, 0.02 and 0.02 μg km-1, respectively. Thus mean PAH emissions of the GDI fleet were 2 orders of magnitude higher than the bench mark diesel vehicle. A comparison of the toxicity equivalent concentrations (TEQ) in the cWLTC of the GDI fleet and the diesel vehicle revealed that GDI vehicles released 200-1700 ng TEQ m-3 genotoxic PAHs, being 6-40 times higher than the diesel vehicle with 45 ng TEQ km-1. The co-release of genotoxic PAHs adsorbed on numerous soot nanoparticles is critical due to the Trojan horse effect

  5. Graphene oxide directed in-situ synthesis of Prussian blue for non-enzymatic sensing of hydrogen peroxide released from macrophages

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, Weiwei; Zhu, Qionghua; Gao, Fei; Gao, Feng [College of Chemistry and Environment, Fujian Province Key Laboratory of Morden Analytical Science and Separation Technology, Minnan Normal University, Zhangzhou 363000 (China); Huang, Jiafu; Pan, Yutian [College of Biological Science and Technology, Minnan Normal University, Zhangzhou 363000 (China); Wang, Qingxiang, E-mail: axiang236@126.com [College of Chemistry and Environment, Fujian Province Key Laboratory of Morden Analytical Science and Separation Technology, Minnan Normal University, Zhangzhou 363000 (China)

    2017-03-01

    A novel electrochemical non-enzymatic hydrogen peroxide (H{sub 2}O{sub 2}) sensor has been developed based on Prussian blue (PB) and electrochemically reduced graphene oxide (ERGO). The GO was covalently modified on glassy carbon electrode (GCE), and utilized as a directing platform for in-situ synthesis of electroactive PB. Then the GO was electrochemically treated to reduction form to improve the effective surface area and electroactivity of the sensing interface. The fabrication process was characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and atomic force microscopy (AFM). The results showed that the rich oxygen containing groups play a crucial role for the successful synthesis of PB, and the obtained PB layer on the covalently immobilized GO has good stability. Electrochemical sensing assay showed that the modified electrode had tremendous electrocatalytic property for the reduction of H{sub 2}O{sub 2}. The steady-state current response increased linearly with H{sub 2}O{sub 2} concentrations from 5 μM to 1 mM with a fast response time (less than 3 s). The detection limit was estimated to be 0.8 μM. When the sensor was applied for determination of H{sub 2}O{sub 2} released from living cells of macrophages, satisfactory results were achieved. - Highlights: • Covalent method was applied for immobilization of GO on glassy carbon electrode. • GO directed in-situ synthesis of electroactive PB. • PB-ERGO composite shows high electrocatalytic activity toward H{sub 2}O{sub 2}. • The modified biosensor is capable of detecting H{sub 2}O{sub 2} released from living macrophages.

  6. Simplified approach for estimating large early release frequency

    International Nuclear Information System (INIS)

    Pratt, W.T.; Mubayi, V.; Nourbakhsh, H.; Brown, T.; Gregory, J.

    1998-04-01

    The US Nuclear Regulatory Commission (NRC) Policy Statement related to Probabilistic Risk Analysis (PRA) encourages greater use of PRA techniques to improve safety decision-making and enhance regulatory efficiency. One activity in response to this policy statement is the use of PRA in support of decisions related to modifying a plant's current licensing basis (CLB). Risk metrics such as core damage frequency (CDF) and Large Early Release Frequency (LERF) are recommended for use in making risk-informed regulatory decisions and also for establishing acceptance guidelines. This paper describes a simplified approach for estimating LERF, and changes in LERF resulting from changes to a plant's CLB

  7. EUROPEAN MARITIME TRANSPORT POLICY

    Directory of Open Access Journals (Sweden)

    Jerzy Kujawa

    2014-03-01

    Full Text Available The article describes the common EU policy on maritime transport, which comprises almost 80% of the volume of external trade of the Union and about 40% of internal transport needs. The first part of the paper presents the origins of the common maritime transport policy and the difficulties encountered during its initial formation. Subsequently, the evolution of the concepts of the policy and its current shape is discussed. The final, substantial part of the article describes the main aims and directions of the EU maritime transport policy and includes an evaluation of the effects of the policy.

  8. A direct healthcare cost analysis of the cryopreserved versus fresh transfer policy at the blastocyst stage.

    Science.gov (United States)

    Papaleo, Enrico; Pagliardini, Luca; Vanni, Valeria Stella; Delprato, Diana; Rubino, Patrizia; Candiani, Massimo; Viganò, Paola

    2017-01-01

    A cost analysis covering direct healthcare costs relating to IVF freeze-all policy was conducted. Normal- and high- responder patients treated with a freeze-all policy (n = 63) compared with fresh transfer IVF (n = 189) matched by age, body mass index, duration and cause of infertility, predictive factors for IVF (number of oocytes used for fertilization) and study period, according to a 1:3 ratio were included. Total costs per patient (€6952 versus €6863) and mean costs per live birth were similar between the freeze-all strategy (€13,101, 95% CI 10,686 to 17,041) and fresh transfer IVF (€15,279, 95% CI 13,212 to 18,030). A mean per live birth cost-saving of €2178 (95% CI -1810 to 6165) resulted in a freeze-all strategy owing to fewer embryo transfer procedures (1.29 ± 0.5 versus 1.41 ± 0.7); differences were not significant. Sensitivity analysis revealed that the freeze-all strategy remained cost-effective until the live birth rate is either higher or only slightly lower (≥-0.59%) in the freeze-all group compared with fresh cycles. A freeze-all policy does not increase costs compared with fresh transfer, owing to negligible additional expenses, i.e. vitrification, endometrial priming and monitoring, against fewer embryo transfer procedures required to achieve pregnancy. Copyright © 2016 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  9. Country policy profile - Bulgaria. April 2015

    International Nuclear Information System (INIS)

    2015-04-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Bulgaria is 16%, whereas in 2012 it reached 17,9%. Renewable electricity in Bulgaria is promoted primarily through a feed-in tariff. Producers are contractually entitled against the grid operator to the purchase and payment of electricity at a guaranteed price. The use of renewable energy for heating and cooling is promoted through a subsidy from the European Regional Development Fund and through an exemption for building owners from property tax. Main Bulgarian support scheme for renewable energy in transport is a quota system. There is a professional training programme for RES-installers as wells as a building obligation for the use of renewable heating and for the exemplary role of public authorities. This report monitors the policy changes after the release of the 2013 Progress Report for Bulgaria and is regularly updated. Recent RES policy changes in Bulgaria involve imposing a fee of 20% on the production of electricity in solar and wind power plants, however this decision was set aside due to the unconstitutional nature of this regulation

  10. Country policy profile - Bulgaria. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Bulgaria is 16%, whereas in 2012 it reached 17,9%. Renewable electricity in Bulgaria is promoted primarily through a feed-in tariff. Producers are contractually entitled against the grid operator to the purchase and payment of electricity at a guaranteed price. The use of renewable energy for heating and cooling is promoted through a subsidy from the European Regional Development Fund and through an exemption for building owners from property tax. Main Bulgarian support scheme for renewable energy in transport is a quota system. There is a professional training programme for RES-installers as wells as a building obligation for the use of renewable heating and for the exemplary role of public authorities. This report monitors the policy changes after the release of the 2013 Progress Report for Bulgaria and is regularly updated. Recent RES policy changes in Bulgaria involve imposing a fee of 20% on the production of electricity in solar and wind power plants, however this decision was set aside due to the unconstitutional nature of this regulation

  11. Generating news media interest in tobacco control; challenges in an advanced policy environment.

    Science.gov (United States)

    MacKenzie, Ross; Chapman, Simon

    2012-08-01

    To determine the efficacy of using media releases for tobacco control advocacy in Australia's advanced policy environment. Between February and August 2010, news releases that summarised either newly published but unpublicized research findings, or local developments in tobacco control, were sent to NSW media outlets. Reports arising from the releases were tracked using commercial services Media Monitors and Factiva, as well as Google and Google News. Other tobacco control related news items during the same period were also tracked and recorded. Twenty-one news releases generated 93 news items across all news media, with a quarter of these related to a story of porcine haemoglobin in cigarette filters. By comparison, 'live' policy issues (especially plain packaging and a significant tobacco tax increase) covered in this period attracted 1,033 news stories in the Australian media. Press releases describing recently published, but underpublicized research were issued in weeks where no major competing tobacco control news occurred. Results of this project indicate that in environments with advanced tobacco policy, media opportunities related to tobacco control advocacy are limited, as many objectives have been achieved. The media can still play a key advocacy role in such environments, and advocates need to be particularly vigilant for opportunities that do arise. The paper also highlights the increasingly important role of internet-based media, including opportunities presented by social media for tobacco control.

  12. Nuclear safety policy statement in korea

    International Nuclear Information System (INIS)

    Kim, W.S.; Kim, H.J.; Choi, K.S.; Choi, Y.S.; Park, D.K.

    2006-01-01

    Full text: Wide varieties of programs to enhance nuclear safety have been established and implemented by the Korean government in accordance with the Nuclear Safety Policy Statement announced in September 1994. The policy statement was intended to set the long-term policy goals for maintaining and achieving high-level of nuclear safety and also help the public understand the national policy and a strong will of the government toward nuclear safety. It has been recognized as very effective in developing safety culture in nuclear-related organizations and also enhancing nuclear safety in Korea. However, ageing of operating nuclear power plants and increasing of new nuclear facilities have demanded a new comprehensive national safety policy to cover the coming decade, taking the implementation results of the policy statement of 1994 and the changing environment of nuclear industries into consideration. Therefore, the results of safety policy implementation have been reviewed and, considering changing environment and future prospects, a new nuclear safety policy statement as a highest level national policy has been developed. The implementation results of 11 regulatory policy directions such as the use of Probabilistic Safety Assessment, introduction of Periodic Safety Review, strengthening of safety research, introduction of Risk Based Regulation stipulated in the safety policy statement of 1994 were reviewed and measures taken after various symposia on nuclear safety held in Nuclear Safety Days since 1995 were evaluated. The changing international and domestic environment of nuclear industry were analysed and future prospects were explored. Based on the analysis and review results, a draft of new nuclear safety policy statement was developed. The draft was finalized after the review of many prominent experts in Korea. Considering changing environment and future prospects, new policy statement that will show government's persistent will for nuclear safety has been

  13. Direct payments as an instrument of the environmental policy Płatności obszarowe jako instrument polityki ochrony środowiska

    Directory of Open Access Journals (Sweden)

    Adrian Sadłowski

    2011-12-01

    Full Text Available Agriculture is the area of human activity that is accompanied by the formation of positive and negative external environmental effects. In order to motivate farmers to conduct production activities in a way that reduces the negative impact of these activities on the environment, the so-called principle of cross compliance has been incorporated into the direct support system. This study characterises the area payments as an instrument of the environmental policy and is a review of the European Commission’s different proposals for the reform of direct payments through the prism of environmental functions of this instrument.

  14. The Impact of the FOMC's Monetary Policy Actions on the growth of Credit Risk: the Monetary Policy - Liquidity Paradox

    OpenAIRE

    Kwamie Dunbar

    2008-01-01

    Credit risk is influenced by interest rates and market liquidity. This paper examines the direct and indirect impacts of unexpected monetary policy shifts on the growth of corporate credit risk, with the aim of quantifying the size and direction of the response. The results surprisingly indicate that monetary policy and liquidity impulses move counter to each other in their effects on credit risk ("The monetary policy-liquidity paradox"). The analysis indicates that while contractionary monet...

  15. ATLAS and CMS Data Release and Tools

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00355153; The ATLAS collaboration

    2016-01-01

    The data collected at the LHC has provided the basis for a vast body of scientific publications and the training of physicists. In light of these benefits it is desirable to also enable people outside the LHC collaborations to profit from the educational opportunities of the LHC data. The goal of the open data initiative is to provide these opportunities by making LHC data available to the general public. This talk will discuss the open data policies of both the ATLAS and CMS document and how these policies are implemented in practice. The open data portal will be presented and the contents made available by the collaborations reviewed emphasising possible use cases. The talk will be concluded with a summary of the plans for upcoming data releases.

  16. Co-operative agreements and the EU Water Framework Directive in conjunction with the Common Agricultural Policy

    Science.gov (United States)

    Heinz, I.

    2008-05-01

    This paper discusses the significance of voluntary arrangements for the water and agricultural policies in the European Union. The current implementation of the European Water Framework Directive (WFD) and the reform of the Common Agricultural Policy (CAP) require new approaches in water management. As many case studies have shown, co-operative agreements (CAs) between water companies, farmers and authorities can help to reduce environmental pressures on water bodies. The main reasons for that are: i) water companies are ready to advise and financially support farmers in changing production methods; ii) changes of farming practices are tailored to the site-specific requirements; iii) farmers and water companies are interested in minimising the costs and environmental pressures as they benefit, for example, from modernization of farming methods, and reductions in cost of water treatment, and iv) voluntarily agreed commitments to change farming practices are often stricter than statutory rules. Moreover, precautionary rather than remedial measures are preferred. Tackling diffuse pollution is one of the main concerns of the WFD. CAs can enhance the cost-effectiveness of actions within the programmes of measures so that good water status is achieved by 2015. In CAs all relevant stakeholders, located in catchment areas of agricultural usage, can be involved. Thus, they can help to foster integrated water resources management. In particular, disproportionate costs of changing farming practices can be identified. With regard to the recent CAP reform, financial support for farmers will be linked to compliance with environmental standards and further commitments. This concerns both direct payments and agri-environmental programmes. The experience gained in CAs can provide information on best agricultural practices. Informed farmers are more ready to meet environmental requirements. Because CAs implement the most cost-effective changes in farming practice, it can be assumed

  17. Electronic U.S. Government Information: Policy Issues and Directions.

    Science.gov (United States)

    Hernon, Peter; McClure, Charles R.

    1993-01-01

    Provides an overview of U.S. federal information policy and its treatment of electronic information resources. Highlights include government publications; electronic government information; main providers of government information, including the Government Printing Office; the Freedom of Information Act; public access and use; information…

  18. PAVAN, Atmospheric Dispersion of Radioactive Releases from Nuclear Power Plants

    International Nuclear Information System (INIS)

    2001-01-01

    1 - Description of program or function: PAVAN estimates down-wind ground-level air concentrations for potential accidental releases of radioactive material from nuclear facilities. Options can account for variation in the location of release points, additional plume dispersion due to building wakes, plume meander under low wind speed conditions, and adjustments to consider non-straight trajectories. It computes an effective plume height using the physical release height which can be reduced by inputted terrain features. 2 - Method of solution: Using joint frequency distributions of wind direction and wind speed by atmospheric stability, the program provides relative air concentration (X/Q) values as functions of direction for various time periods at the exclusion area boundary (EAB) and the outer boundary of the low population zone (LPZ). Calculations of X/Q values can be made for assumed ground-level releases or evaluated releases from free-standing stacks. The X/Q calculations are based on the theory that material released to the atmosphere will be normally distributed (Gaussian) about the plume centerline. A straight-line trajectory is assumed between the point of release and all distances for which X/Q values are calculated. 3 - Restrictions on the complexity of the problem: - The code cannot handle multiple emission sources

  19. The impact of the treaty basis on health policy legislation in the European Union: A case study on the tobacco advertising directive

    Directory of Open Access Journals (Sweden)

    Maarse Hans

    2008-04-01

    Full Text Available Abstract Background The Europe Against Cancer programme was initiated in the late 1980s, recognising, among other risk factors, the problematic relationship between tobacco use and cancer. In an attempt to reduce the number of smokers in the European Community, the European Commission proposed a ban on tobacco advertising. The question of why it took over ten years of negotiating before the EU adopted a policy measure that could in fact improve the health situation in the Community, can only be answered by focusing on politics. Methods We used an actor-centred institutionalist approach, focusing on the strategic behaviour of the major actors involved. We concentrated our analysis on the legal basis as an important institution and evaluated how the absence of a proper legal basis for public health measures in the Treaties influenced policy-making, framing the discussion in market-making versus market-correcting policy interventions. For our analysis, we used primary and secondary sources, including policy documents, communications and press releases. We also conducted 9 semi-structured interviews. Results The ban on tobacco advertising was, in essence, a public health measure. The Commission used its agenda-setting power and framed the market-correcting proposal in market-making terms. The European Parliament and the Council of Ministers then used the discussion on the legal basis as a vehicle for real political controversies. After adoption of the ban on tobacco advertising, Germany appealed to the European Court of Justice, which annulled the ban but also offered suggestions for a possible solution with article 100a as the legal basis. Conclusion The whole market-making versus market-correcting discussion is related to a broader question, namely how far European health regulation can go in respect to the member states. In fact, the policy-making process of a tobacco advertising ban, as described in this paper, is related to the 'constitutional

  20. The impact of the treaty basis on health policy legislation in the European Union: a case study on the tobacco advertising directive.

    Science.gov (United States)

    Boessen, Sandra; Maarse, Hans

    2008-04-08

    The Europe Against Cancer programme was initiated in the late 1980s, recognising, among other risk factors, the problematic relationship between tobacco use and cancer. In an attempt to reduce the number of smokers in the European Community, the European Commission proposed a ban on tobacco advertising. The question of why it took over ten years of negotiating before the EU adopted a policy measure that could in fact improve the health situation in the Community, can only be answered by focusing on politics. We used an actor-centred institutionalist approach, focusing on the strategic behaviour of the major actors involved. We concentrated our analysis on the legal basis as an important institution and evaluated how the absence of a proper legal basis for public health measures in the Treaties influenced policy-making, framing the discussion in market-making versus market-correcting policy interventions. For our analysis, we used primary and secondary sources, including policy documents, communications and press releases. We also conducted 9 semi-structured interviews. The ban on tobacco advertising was, in essence, a public health measure. The Commission used its agenda-setting power and framed the market-correcting proposal in market-making terms. The European Parliament and the Council of Ministers then used the discussion on the legal basis as a vehicle for real political controversies. After adoption of the ban on tobacco advertising, Germany appealed to the European Court of Justice, which annulled the ban but also offered suggestions for a possible solution with article 100a as the legal basis. The whole market-making versus market-correcting discussion is related to a broader question, namely how far European health regulation can go in respect to the member states. In fact, the policy-making process of a tobacco advertising ban, as described in this paper, is related to the 'constitutional' foundation of health policy legislation in the Community. The

  1. Formulating Public Policy in Croatia and the Problem of Policy Coordination

    Directory of Open Access Journals (Sweden)

    Zdravko Petak

    2008-01-01

    Full Text Available The paper explores the role of politicians and civil servants in the process of horizontal and vertical policy coordination, with a special emphasis on the specific context of Croatia. Starting from Guy Peters’ typology, which distinguishes four distinct types of coordination, ranging from more simple to more complex ones – negative coordination, positive coordination, policy integration and development of strategies for government, the author stresses that the Croatian case is connected with failure in achieving all types of coordination. One of the reasons for such a situation lies in a low level of applying classical policy analysis in the Croatian public administration system. A direct consequence of this is the existence of the system of coordination based on ad hoc assessment of proposed policies, and not on standard policy analysis tools. Therefore, in the lack of central government policy unit the prominent role in such a system belongs to the finance Minister, who serves as some kind of “policy switchman”.

  2. 34 CFR 361.38 - Protection, use, and release of personal information.

    Science.gov (United States)

    2010-07-01

    ... through appropriate modes of communication of the confidentiality of personal information and the... individual's native language or through the appropriate mode of communication; and (v) These policies and... the record of services, consistent with § 361.47(a)(12). (d) Release for audit, evaluation, and...

  3. Local control of striatal dopamine release

    Directory of Open Access Journals (Sweden)

    Roger eCachope

    2014-05-01

    Full Text Available The mesolimbic and nigrostriatal dopamine (DA systems play a key role in the physiology of reward seeking, motivation and motor control. Importantly, they are also involved in the pathophysiology of Parkinson’s and Huntington’s disease, schizophrenia and addiction. Control of DA release in the striatum is tightly linked to firing of DA neurons in the ventral tegmental area (VTA and the substantia nigra (SN. However, local influences in the striatum affect release by exerting their action directly on axon terminals. For example, endogenous glutamatergic and cholinergic activity is sufficient to trigger striatal DA release independently of cell body firing. Recent developments involving genetic manipulation, pharmacological selectivity or selective stimulation have allowed for better characterization of these phenomena. Such termino-terminal forms of control of DA release transform considerably our understanding of the mesolimbic and nigrostriatal systems, and have strong implications as potential mechanisms to modify impaired control of DA release in the diseased brain. Here, we review these and related mechanisms and their implications in the physiology of ascending DA systems.

  4. Nuclear power and public policy

    International Nuclear Information System (INIS)

    Shrader-Frechette, K.S.

    1980-01-01

    The authors' purpose is to raise some of the social, political, and ethical issues which for so long have been ignored in making government assessments of nuclear power. In particular she asks whether current policy (governing admissible releases of radioactivity during electricity generation) is based on sound ethical premises. She argues that it is ethically reprehensible to generate long-lived nuclear wastes without knowing whether they can be safety stored. An ethical and methodological assessment of public policy is presented based on the presupposition that a core melt accident is improbable. It is then argued that the alleged cost-effectiveness of fission generated electricity is based on economical methodology which is both illogical and unethical. Finally, an outline of the sorts of policy-making procedures which ought to be followed in dealing with nuclear technology is given. (Auth.)

  5. 5 CFR 1310.1 - Policy guidelines.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Policy guidelines. 1310.1 Section 1310.1 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES OMB CIRCULARS § 1310.1 Policy guidelines. In carrying out its responsibilities, the Office of Management and Budget issues policy guidelines to...

  6. Argentina's radioactive waste disposal policy

    International Nuclear Information System (INIS)

    Palacios, E.

    1986-01-01

    The Argentina policy for radioactive waste disposal from nuclear facilities is presented. The radioactive wastes are treated and disposed in confinement systems which ensure the isolation of the radionucles for an appropriate period. The safety criteria adopted by Argentina Authorities in case of the release of radioactive materials under normal conditions and in case of accidents are analysed. (M.C.K.) [pt

  7. Modeling Nutrient Release in the Tai Lake Basin of China: Source Identification and Policy Implications

    Science.gov (United States)

    Liu, Beibei; Liu, Heng; Zhang, Bing; Bi, Jun

    2013-03-01

    Because nutrient enrichment has become increasingly severe in the Tai Lake Basin of China, identifying sources and loads is crucial for watershed nutrient management. This paper develops an empirical framework to estimate nutrient release from five major sectors, which requires fewer input parameters and produces acceptable accuracy. Sectors included are industrial manufacturing, livestock breeding (industrial and family scale), crop agriculture, household consumption (urban and rural), and atmospheric deposition. Results show that in the basin (only the five sectors above), total nutrient loads of nitrogen (N) and phosphorus (P) into aquatic systems in 2008 were 33043.2 tons N a-1 and 5254.4 tons P a-1, and annual area-specific nutrient loads were 1.94 tons N km-2 and 0.31 tons P km-2. Household consumption was the major sector having the greatest impact (46 % in N load, 47 % in P load), whereas atmospheric deposition (18 %) and crop agriculture (15 %) sectors represented other significant proportions of N load. The load estimates also indicate that 32 % of total P came from the livestock breeding sector, making it the second largest phosphorus contributor. According to the nutrient pollution sectors, six best management practices are selected for cost-effectiveness analysis, and feasible options are recommended. Overall, biogas digester construction on industrial-scale farms is proven the most cost-effective, whereas the building of rural decentralized facilities is the best alternative under extreme financial constraint. However, the reduction potential, average monetary cost, and other factors such as risk tolerance of policy makers should all be considered in the actual decision-making process.

  8. Oxaliplatin loaded PLAGA microspheres: design of specific release profiles.

    Science.gov (United States)

    Lagarce, F; Cruaud, O; Deuschel, C; Bayssas, M; Griffon-Etienne, G; Benoit, J

    2002-08-21

    Oxaliplatin loaded PLAGA microspheres have been prepared by solvent extraction process. Parameters affecting the release kinetics in vitro have been studied in order to design specific release profiles suitable for direct intra-tumoral injection. By varying the nature and the relative proportions of different polymers we managed to prepare microspheres with good encapsulation efficiency (75-90%) and four different release profiles: zero order kinetics (type II) and the classical sigmoïd release profile with three different sizes of plateau and burst. These results, if correlated with in vivo activity, are promising to enhance effectiveness of local tumor treatment.

  9. Educational Elements of a Comprehensive State Policy on Aging.

    Science.gov (United States)

    New York State Education Dept., Albany. Center for Educational and Cultural Opportunities for the Aging.

    This document, a policy statement adopted by the New York State Board of Regents in 1986, describes program options to implement each of six policy directions adopted by the Regents and to be coordinated by the Center for Educational and Cultural Opportunities for the Aging. The six policy directions are (1) involve the elderly as active…

  10. New Directions in Land Remote Sensing Policy and International Cooperation

    Science.gov (United States)

    Stryker, Timothy

    2010-12-01

    Recent changes to land remote sensing satellite data policies in Brazil and the United States have led to the phenomenal growth in the delivery of land imagery to users worldwide. These new policies, which provide free and unrestricted access to land remote sensing data over a standard electronic interface, are expected to provide significant benefits to scientific and operational users, and open up new areas of Earth system science research and environmental monitoring. Freely-available data sets from the China-Brazil Earth Resources Satellites (CBERS), the U.S. Landsat satellites, and other satellite missions provide essential information for land surface monitoring, ecosystems management, disaster mitigation, and climate change research. These missions are making important contributions to the goals and objectives of regional and global terrestrial research and monitoring programs. These programs are in turn providing significant support to the goals and objectives of the United Nations Framework Convention on Climate Change (UN FCCC), the Global Earth Observation System of Systems (GEOSS), and the UN Reduction in Emissions from Deforestation and Degradation (REDD) program. These data policies are well-aligned with the "Data Democracy" initiative undertaken by the international Committee on Earth Observation Satellites (CEOS), through its current Chair, Brazil's National Institute for Space Research (Instituto Nacional de Pesquisas Espaciais, or INPE), and its former chairs, South Africa's Council for Scientific and Industrial Research (CSIR) and Thailand's Geo Informatics and Space Technology Development Agency (GISTDA). Comparable policies for land imaging data are under consideration within Europe and Canada. Collectively, these initiatives have the potential to accelerate and improve international mission collaboration, and greatly enhance the access, use, and application of land surface imagery for environmental monitoring and societal adaption to changing

  11. Modeling Security-Enhanced Linux Policy Specifications for Analysis (Preprint)

    National Research Council Canada - National Science Library

    Archer, Myla; Leonard, Elizabeth; Pradella, Matteo

    2003-01-01

    Security-Enhanced (SE) Linux is a modification of Linux initially released by NSA in January 2001 that provides a language for specifying Linux security policies and, as in the Flask architecture, a security server...

  12. Introducing a new operational policy : the PIS operational policy

    CSIR Research Space (South Africa)

    Pattinson, T

    2009-01-01

    Full Text Available ; No. of Pages 14 Computers and Chemical Engineering xxx (2009) xxx–xxx Contents lists available at ScienceDirect Computers and Chemical Engineering journa l homepage: www.e lsev ier .com/ locate /compchemeng Introducing a new operational policy...), • Finite Intermediate Storage (FIS), • Unlimited Intermediate Storage (UIS), ARTICLE IN PRESSG ModelCACE-3875; No. of Pages 14 2 T. Pattinson, T. Majozi / Computers and Chemical Engineering xxx (2009) xxx–xxx W situatio ationa polic u CI policie...

  13. Sulphur release from alternative fuel firing

    DEFF Research Database (Denmark)

    Cortada Mut, Maria del Mar; Nørskov, Linda Kaare; Glarborg, Peter

    2014-01-01

    The cement industry has long been dependent on the use of fossil fuels, although a recent trend in replacing fossil fuels with alternative fuels has arisen. 1, 2 However, when unconverted or partly converted alternative fuels are admitted directly in the rotary kiln inlet, the volatiles released...... from the fuels may react with sulphates present in the hot meal to form SO 2 . Here Maria del Mar Cortada Mut and associates describe pilot and industrial scale experiments focusing on the factors that affect SO 2 release in the cement kiln inlet....

  14. Advanced health biotechnologies in Thailand: redefining policy directions.

    Science.gov (United States)

    Velasco, Román Pérez; Chaikledkaew, Usa; Myint, Chaw Yin; Khampang, Roongnapa; Tantivess, Sripen; Teerawattananon, Yot

    2013-01-02

    Thailand faces a significant burden in terms of treating and managing degenerative and chronic diseases. Moreover, incidences of rare diseases are rising. Many of these-such as diabetes, cancer, and inherited inborn metabolic diseases-have no definite treatments or cure. Meanwhile, advanced health biotechnology has been found, in principle, to be an effective solution for these health problems. Qualitative approaches were employed to analyse the current situation and examine existing public policies related to advanced health biotechnologies in Thailand. The results of this analysis were then used to formulate policy recommendations. Our research revealed that the system in Thailand in relation to advanced health biotechnologies is fragmented, with multiple unaddressed gaps, underfunding of research and development (R&D), and a lack of incentives for the private sector. In addition, there are no clear definitions of advanced health biotechnologies, and coverage pathways are absent. Meanwhile, false advertising and misinformation are prevalent, with no responsible bodies to actively and effectively provide appropriate information and education (I&E). The establishment of a specialised institution to fill the gaps in this area is warranted. The development and implementation of a comprehensive national strategic plan related to advanced health biotechnologies, greater investment in R&D and I&E for all stakeholders, collaboration among agencies, harmonisation of reimbursement across public health schemes, and provision of targeted I&E are specifically recommended.

  15. Experimental study of PLLA/INH slow release implant fabricated by three dimensional printing technique and drug release characteristics in vitro.

    Science.gov (United States)

    Wu, Gui; Wu, Weigang; Zheng, Qixin; Li, Jingfeng; Zhou, Jianbo; Hu, Zhilei

    2014-07-19

    Local slow release implant provided long term and stable drug release in the lesion. The objective of this study was to fabricate biodegradable slow release INH/PLLA tablet via 3 dimensional printing technique (3DP) and to compare the drug release characteristics of three different structured tablets in vitro. Three different drug delivery systems (columnar-shaped tablet (CST), doughnut-shaped tablet (DST) and multilayer doughnut-shaped tablet (MDST)) were manufactured by the three dimensional printing machine and isoniazid was loaded into the implant. Dynamic soaking method was used to study the drug release characteristics of the three implants. MTT cytotoxicity test and direct contact test were utilized to study the biocompatibility of the implant. The microstructures of the implants' surfaces were observed with electron microscope. The PLLA powder in the tablet could be excellently combined through 3DP without disintegration. Electron microscope observations showed that INH distributed evenly on the surface of the tablet in a "nest-shaped" way, while the surface of the barrier layer in the multilayer doughnut shaped tablet was compact and did not contain INH. The concentration of INH in all of the three tablets were still higher than the effective bacteriostasis concentration (Isoniazid: 0.025 ~ 0.05 μg/ml) after 30 day's release in vitro. All of the tablets showed initial burst release of the INH in the early period. Drug concentration of MDST became stable and had little fluctuation starting from the 6th day of the release. Drug concentration of DST and CST decreased gradually and the rate of decrease in concentration was faster in DST than CST. MTT cytotoxicity test and direct contact test indicated that the INH-PLLA tablet had low cytotoxicity and favorable biocompatibility. Three dimensional printing technique was a reliable technique to fabricate complicated implants. Drug release pattern in MDST was the most stable among the three implants. It was

  16. Natural and technologic hazardous material releases during and after natural disasters: a review.

    Science.gov (United States)

    Young, Stacy; Balluz, Lina; Malilay, Josephine

    2004-04-25

    Natural disasters may be powerful and prominent mechanisms of direct and indirect hazardous material (hazmat) releases. Hazardous materials that are released as the result of a technologic malfunction precipitated by a natural event are referred to as natural-technologic or na-tech events. Na-tech events pose unique environmental and human hazards. Disaster-associated hazardous material releases are of concern, given increases in population density and accelerating industrial development in areas subject to natural disasters. These trends increase the probability of catastrophic future disasters and the potential for mass human exposure to hazardous materials released during disasters. This systematic review summarizes direct and indirect disaster-associated releases, as well as environmental contamination and adverse human health effects that have resulted from natural disaster-related hazmat incidents. Thorough examination of historic disaster-related hazmat releases can be used to identify future threats and improve mitigation and prevention efforts.

  17. Commissions of audit in Australia: health system privatisation directives and civil conscription protections.

    Science.gov (United States)

    Colton, Caroline; Faunce, Thomas

    2014-03-01

    The use of commissions of audit as vehicles to drive privatisation policy agendas in areas such as health service delivery has become popular with conservative federal and State governments. Such commissions have characteristically been established early in the terms of such governments with carefully planned terms of reference and membership. The policy directions they advocate, unlike election policies, have not come under the intense scrutiny, wide public debate or the opportunities for (dis)endorsement afforded by the electoral process. Governments do, however, anticipate and often accept recommendations from these reviews, and use them as justification to implement policy based on their findings. This highlights the power entrusted to review bodies and the risks to the public interest arising from limited public consultation. An example can be seen in the proposed privatisation of important aspects of Australia's public sector, particularly including those related to health systems delivery, currently entering a new iteration through the work of the National Commission of Audit appointed in October 2013. The NCA follows on from various State audit commissions which in recent years have directed the divestment of government responsibilities to the private and not-for-profit sectors. Through a discussion on the formation of policy frameworks by the NCA and the Queensland Commission of Audit, this column examines the ideological thrust of the commissions and how they synergise to produce a national directive on the future of public sector health services. The practical impacts on health service procurement and delivery in critical areas are examined, using the case of the federally contracted out medical service for asylum seekers and two hospitals in Western Australia, a State which is well advanced in the privatisation of public hospitals. The column then examines the release to the media early in the NCA's process of the submission to introduce a $6 general

  18. Policy options to reduce consumer waste to zero: comparing product stewardship and extended producer responsibility for refrigerator waste.

    Science.gov (United States)

    Nicol, Scott; Thompson, Shirley

    2007-06-01

    Today, over-consumption, pollution and resource depletion threaten sustainability. Waste management policies frequently fail to reduce consumption, prevent pollution, conserve resources and foster sustainable products. However, waste policies are changing to focus on lifecycle impacts of products from the cradle to the grave by extending the responsibilities of stakeholders to post-consumer management. Product stewardship and extended producer responsibility are two policies in use, with radically different results when compared for one consumer product, refrigerators. North America has enacted product stewardship policies that fail to require producers to take physical or financial responsibility for recycling or for environmentally sound disposal, so that releases of ozone depleting substances routinely occur, which contribute to the expanding the ozone hole. Conversely, Europe's Waste Electrical and Electronic Equipment (WEEE) Directive requires extended producer responsibility, whereby producers collect and manage their own post-consumer waste products. WEEE has resulted in high recycling rates of greater than 85%, reduced emissions of ozone-depleting substances and other toxins, greener production methods, such as replacing greenhouse gas refrigerants with environmentally friendly hydrocarbons and more reuse of refrigerators in the EU in comparison with North America.

  19. Implementation of Releasing Time to Care - the productive ward.

    Science.gov (United States)

    Wilson, Gwyneth

    2009-07-01

    This paper describes the implementation of the NHS Institute for Innovation and Improvement Productive Ward - releasing time to care programme. It will discuss the benefits and key successes and provides advice for those wishing to implement the programme. In Lord Darzi's Next Stage Review, he advocates an ambitious vision of patient centred - clinician led, locally driven NHS. The Releasing Time to Care programme is a unique opportunity for everyone working within the NHS to improve effectiveness, safety and reliability of the services we provide. Whilst being situated within a National Health Service policy environment learning from this work can be translated nationally and internationally, as the principles underpin the provision of high quality care. Evaluation is currently in relation to each of the 15 modules rather than as the programme as a whole. It uses various methods including audit, observation, activity follow through, satisfaction surveys and process mapping. Each month data is colated for each of the 11 metrics which has shown a reduction in falls, drug administration errors and improvement in the recording of patient observations. One of the key issues is that an essential component for the success of the programme lies in the tangible support of the Trust Board/Board of Directors. Evidence shows that this programme improves patient satisfaction as it enables the provision of an increase in direct patient care by staff and subsequently improved clinical and safety outcomes. Ward Sister/Charge Nurse development includes Leadership, Project management and Lean Methodology techniques. The Releasing Time to Care programme is a key component of the Next Stage Review. It will create productive organisations by being a catalyst for the transformation of Trust services, enabling staff to spend more time caring for patients and users. This release in time will result in better outcomes and subsequent improvement with patient and staff satisfaction and

  20. Development of theophylline sustained release dosage form based on Kollidon SR.

    Science.gov (United States)

    Reza, Md Selim; Quadir, Mohiuddin Abdul; Haider, Syed Shabbir

    2002-01-01

    Sustained release theophylline matrix tablets constituting Kollidon SR (Polyvinyl acetate and povidone based matrix retarding polymer) were developed in this study in an attempt to design a dosage form that manifests desirable release profile and thorough adherence to official monographs. Four matrix tablet formulations were prepared by dry blending and direct compression of Kollidon SR and HPMC-15cps (hydroxypropylmethylcellulose) in varying proportion with fixed percentage of theophylline. Tablets containing only Kollidon SR with the active ingredient demonstrated a rapid rate of drug release with an initial burst effect. Incorporation of HPMC-15cps in the matrix tablet prolonged the release of drug with subsequent minimization of burst effect as confirmed by mean dissolution time, T50 and Higuchi release rate data. Among the batches containing HPMC-15 cps, a direct relationship was obtained between release rate and the percentage of HPMC used. A suitable controlled release profile was obtained with the matrix tablets containing 20% Kollidon SR and 30% HPMC-15cps. The formulation showed close resemblance to commercial products and compliance with USP specification. The results were explored and explained by the difference of physico-chemical property and hydration characteristics of the polymers. In addition to this result, the exponential model was applied to characterize the drug release behaviour from polymeric systems. It was found that, Fickian release is predominant in tablets containing Kollidon SR alone and non-Fickian mechanism plays an important role in the release of drug from HPMC containing tablets with a trend towards zero-order or case II release. In vitro release profile of two commercial brands were also undertaken for comparison and modulation of the experimental batches.

  1. The Use of Evidence in Public Debates in the Media: The Case of Swiss Direct-Democratic Campaigns in the Health Policy Sector

    Science.gov (United States)

    Stucki, Iris

    2016-01-01

    This article analyses the reporting of evidence in Swiss direct-democratic campaigns in the health policy sector, assuming that an informed public helps democracy function successfully. A content analysis of the media's news reporting shows that of 5030 media items retrieved, a reference to evidence is found in 6.8%. The voter receives evidence in…

  2. Is group A thawed plasma suitable as the first option for emergency release transfusion? (CME).

    Science.gov (United States)

    Chhibber, Vishesh; Greene, Mindy; Vauthrin, Michelle; Bailey, Jeff; Weinstein, Robert

    2014-07-01

    Group AB plasma, which lacks anti-A and anti-B isohemagglutinins, is issued for emergency transfusion when a patient's ABO group is unknown, but the relative scarcity of group AB blood donors limits its availability. We sought to establish a thawed plasma inventory to improve the rapid availability of plasma in the emergency release setting but were concerned about potential wastage of group AB plasma. Recognizing that plasma-incompatible apheresis platelets are routinely transfused and only rarely result in hemolytic reactions if the donor is blood group O, and considering that group A plasma would be compatible with approximately 85% of our patient population, we instituted an emergency release policy whereby thawed group A plasma is issued to all patients of unknown blood group or if compatible plasma is not available. ABO-compatible plasma is then issued, if needed, once the patient's blood group is determined. We prospectively assessed the outcomes of all patients who received incompatible plasma under our policy. During the first 5 years under this policy, 385 emergency release requests for plasma were received by our blood bank. Among them, 23 group B or AB patients met criteria for receiving a median of 2 units of incompatible group A plasma. No hemolytic transfusion reactions or other adverse events related to transfusion were seen in any of these 23 patients. We propose that group A plasma may be an acceptable alternative to AB plasma as the first option in the emergency release setting. © 2014 AABB.

  3. 25 CFR 63.2 - Policy.

    Science.gov (United States)

    2010-04-01

    ... AFFAIRS, DEPARTMENT OF THE INTERIOR TRIBAL GOVERNMENT INDIAN CHILD PROTECTION AND FAMILY VIOLENCE PREVENTION Purpose, Policy, and Definitions § 63.2 Policy. In enacting the Indian Child Protection and Family... and integrity of Indian tribes than their children and that the United States has a direct interest...

  4. Policy harmonized approach for the EU agricultural sector modelling

    Directory of Open Access Journals (Sweden)

    G. SALPUTRA

    2008-12-01

    Full Text Available Policy harmonized (PH approach allows for the quantitative assessment of the impact of various elements of EU CAP direct support schemes, where the production effects of direct payments are accounted through reaction prices formed by producer price and policy price add-ons. Using the AGMEMOD model the impacts of two possible EU agricultural policy scenarios upon beef production have been analysed – full decoupling with a switch from historical to regional Single Payment scheme or alternatively with re-distribution of country direct payment envelopes via introduction of EU-wide flat area payment. The PH approach, by systematizing and harmonizing the management and use of policy data, ensures that projected differential policy impacts arising from changes in common EU policies reflect the likely actual differential impact as opposed to differences in how “common” policies are implemented within analytical models. In the second section of the paper the AGMEMOD model’s structure is explained. The policy harmonized evaluation method is presented in the third section. Results from an application of the PH approach are presented and discussed in the paper’s penultimate section, while section 5 concludes.;

  5. Energy Policy Act of 2005 and Underground Storage Tanks (USTs)

    Science.gov (United States)

    The Energy Policy Act of 2005 significantly affected federal and state underground storage tank programs, required major changes to the programs, and is aimed at reducing underground storage tank releases to our environment.

  6. Advanced health biotechnologies in Thailand: redefining policy directions

    Directory of Open Access Journals (Sweden)

    Velasco Román Pérez

    2013-01-01

    Full Text Available Abstract Background Thailand faces a significant burden in terms of treating and managing degenerative and chronic diseases. Moreover, incidences of rare diseases are rising. Many of these—such as diabetes, cancer, and inherited inborn metabolic diseases—have no definite treatments or cure. Meanwhile, advanced health biotechnology has been found, in principle, to be an effective solution for these health problems. Methods Qualitative approaches were employed to analyse the current situation and examine existing public policies related to advanced health biotechnologies in Thailand. The results of this analysis were then used to formulate policy recommendations. Results Our research revealed that the system in Thailand in relation to advanced health biotechnologies is fragmented, with multiple unaddressed gaps, underfunding of research and development (R&D, and a lack of incentives for the private sector. In addition, there are no clear definitions of advanced health biotechnologies, and coverage pathways are absent. Meanwhile, false advertising and misinformation are prevalent, with no responsible bodies to actively and effectively provide appropriate information and education (I&E. The establishment of a specialised institution to fill the gaps in this area is warranted. Conclusion The development and implementation of a comprehensive national strategic plan related to advanced health biotechnologies, greater investment in R&D and I&E for all stakeholders, collaboration among agencies, harmonisation of reimbursement across public health schemes, and provision of targeted I&E are specifically recommended.

  7. Considerations When Including Students with Disabilities in Test Security Policies. NCEO Policy Directions. Number 23

    Science.gov (United States)

    Lazarus, Sheryl; Thurlow, Martha

    2015-01-01

    Sound test security policies and procedures are needed to ensure test security and confidentiality, and to help prevent cheating. In this era when cheating on tests draws regular media attention, there is a need for thoughtful consideration of the ways in which possible test security measures may affect accessibility for some students with…

  8. Environmental and sustainability education policy

    DEFF Research Database (Denmark)

    The volume draws on a wide range of policy studies and syntheses to provide readers with insights into the international genealogy and priorities of ESE policy. Editors and contributors call for renewed attention to the possibilities for future directions in light of previously published work and......, ideological orthodoxy and critique, curriculum making and educational theory, globalisation and neoliberalism, climate change and environmental worldviews, and much more....... and innovations in scholarship. They also offer critical commentary on the evolution of research trends, approaches and findings. Including a wide range of examples of ESE policy and policy research, the book draws on studies of educational initiatives and legislation, policy making processes and rhetoric...

  9. Sustainable winter cities: Future directions for planning, policy and design

    Science.gov (United States)

    Pressman, Norman E. P.

    Attempts to generate a "climate-responsive" northern urban form are part of a relatively recent phenomenon and field of investigation. In conjunction with the international "winter cities" movement, the need has been established for explicit, systematic inquiry directed toward national and local action to improve the comfort and lifestyles of all northern inhabitants. It is important to recognize that winter-induced discomforts exist and that they must be acknowledged in planning theory and practice. For northern cities to function more satisfactorily, the negative impacts of winter must be reduced while its beneficial characteristics are enhanced. While not all summer activities can or should be abandoned during winter, proper micro-climatic control is essential if human life is to be retained outside. The outdoor season should be extended since so much indoor isolation occurs. The main principles to be incorporated in exemplary "winter city" design should be contact with nature, year-round usability, user participation, cultural continuity, and the creation of comfortable micro-climatic conditions throughout much of the city's open spaces. All valuable sources of inspiration must be harnessed in the attempt to mediate between organic regionalism and internationalism, on the one hand, and romanticism and pragmatic realism, on the other. Creating optimum conditions for human well-being, habitation, work and intellectual development in each of the four seasons is vital under harsh environments. Adopting a climate-sensitive approach to planning policy and urban design can render everyday life less stressful, especially during the lengthy winter periods found in many northern latitude and high altitude settings.

  10. EPICS release 3.11.6 specific documentation -- Release notes for EPICS 3.11.6

    International Nuclear Information System (INIS)

    1994-01-01

    These notes cover the following: (1) directions for switching to production APS release R3.11.6; (2) unbundling of channel access clients; (3) access security; (4) channel access additions; synchronous time support; and (5) description of major differences between R3.11.3 and R3.11.6 Also included is a list of new and/or updated documentation for the program

  11. Applying Behavioral Economics to Public Health Policy: Illustrative Examples and Promising Directions.

    Science.gov (United States)

    Matjasko, Jennifer L; Cawley, John H; Baker-Goering, Madeleine M; Yokum, David V

    2016-05-01

    Behavioral economics provides an empirically informed perspective on how individuals make decisions, including the important realization that even subtle features of the environment can have meaningful impacts on behavior. This commentary provides examples from the literature and recent government initiatives that incorporate concepts from behavioral economics in order to improve health, decision making, and government efficiency. The examples highlight the potential for behavioral economics to improve the effectiveness of public health policy at low cost. Although incorporating insights from behavioral economics into public health policy has the potential to improve population health, its integration into government public health programs and policies requires careful design and continual evaluation of such interventions. Limitations and drawbacks of the approach are discussed. Copyright © 2016 American Journal of Preventive Medicine. All rights reserved.

  12. A multi-level analysis of the EU linking directive process: the controversial connection between EU and global climate policy

    Energy Technology Data Exchange (ETDEWEB)

    Flaam, Karoline Haegstad

    2007-10-15

    Despite initial scepticism in the EU towards the Kyoto Protocol's project mechanisms (the CDM and JI), the 'Linking Directive' was adopted in October 2004, connecting the EU emissions trading scheme with the project mechanisms. Not only was the Linking Directive settled remarkably quickly, the decision-making process also left a more liberal text, with fewer restrictions on the use of the project mechanisms, as compared to the initial directive proposal. This report examines possible explanations to this puzzle, evaluating whether Member State preferences, EU institutions or external influence from the climate regime best can contribute to understanding the process. On the basis of the analysis of written sources stemming from the decision-making process, as well as seven in-depth interviews, the report finds that Member State preferences were the main driver in the Linking Directive process. This gives support to the intergovernmentalist mantra, that Member States are the main decision-makers in the EU. It also challenges much recent research claiming that EU policy-making is increasingly being taken out of the hands of the nation-state and into supranational actors such as the Commission and the European Parliament. (author). 41 refs., figs., tabs

  13. A multi-level analysis of the EU linking directive process: the controversial connection between EU and global climate policy

    Energy Technology Data Exchange (ETDEWEB)

    Flaam, Karoline Haegstad

    2007-10-15

    Despite initial scepticism in the EU towards the Kyoto Protocol's project mechanisms (the CDM and JI), the 'Linking Directive' was adopted in October 2004, connecting the EU emissions trading scheme with the project mechanisms. Not only was the Linking Directive settled remarkably quickly, the decision-making process also left a more liberal text, with fewer restrictions on the use of the project mechanisms, as compared to the initial directive proposal. This report examines possible explanations to this puzzle, evaluating whether Member State preferences, EU institutions or external influence from the climate regime best can contribute to understanding the process. On the basis of the analysis of written sources stemming from the decision-making process, as well as seven in-depth interviews, the report finds that Member State preferences were the main driver in the Linking Directive process. This gives support to the intergovernmentalist mantra, that Member States are the main decision-makers in the EU. It also challenges much recent research claiming that EU policy-making is increasingly being taken out of the hands of the nation-state and into supranational actors such as the Commission and the European Parliament. (author). 41 refs., figs., tabs

  14. Progress in tourism planning and policy

    DEFF Research Database (Denmark)

    Dredge, Dianne; Jamal, Tazim

    2015-01-01

    This paper examines progress in tourism planning and policy knowledge and identifies gaps and future directions for research. The study employs a post-structuralist perspective presented in two analytical movements: a bibliographic study of tourism policy and planning publications in Scopus...

  15. Direct observation of the release of alkali vapor species in biofuel combustion and gasification

    Energy Technology Data Exchange (ETDEWEB)

    French, R.J.; Milne, T.A. [National Renewable Energy Lab., Golden, CO (United States)

    1993-12-31

    The largest present use of biomass for energy is in combustion for steam and electrical power. Biofuels have an acknowledged advantage over coal as a solid fuel because of their low sulfur and ash content. However, some forms of biomass have substantial quantities of alkali metals and chlorine. In addition, evidence indicates that the alkali in biomass is largely atomically dispersed, resulting in its facile mobilization into the gas-phase. Gaseous alkali compounds aggravate problems of slagging, fouling, and corrosion on heat transfer surfaces in present-day boilers. These problems can be particularly severe when mixed and variable agricultural residues are burned. Furthermore, the next generation of biomass-to-power systems will likely involve combined cycle gas turbines, where alkali tolerances are especially restrictive. In this paper, we report on laboratory studies in which biofuels are combusted under simulated turbine or boiler-firing conditions. Gaseous alkali, sulfur, nitrogen, and halogen-containing species are measured by direct extraction from the hot gases through molecular-beam mass spectrometry (MBMS). The experimental apparatus will be described and its capability illustrated with results of time-resolved evolution of species like K, KCl, KOH, SO{sub 2} and NO{sub x} from small samples of biomass in combustion environments. The nature and release of such species will be explicated by referring to thermodynamic equilibrium predictions and the form of alkali in solid, gaseous, and liquid biofuels.

  16. Environmental macroeconomics : Environmental policy, business cycles, and directed technical change

    NARCIS (Netherlands)

    Fischer, Carolyn; Heutel, Garth

    Environmental economics has traditionally fallen in the domain of microeconomics, but approaches from macroeconomics have recently been applied to studying environmental policy. We focus on two macroeconomic tools and their application to environmental economics. First, real-business-cycle models

  17. Formulation and evaluation of sustained release matrix tablets of pioglitazone hydrochloride using processed Aloe vera mucilage as release modifier

    Directory of Open Access Journals (Sweden)

    Manoj Choudhary

    2015-01-01

    Full Text Available Background: Natural gums and mucilage which hydrates and swells on contact with aqueous media are used as additives in the formulation of hydrophilic drug delivery system. Aim: The purpose of this study was to develop a new monolithic matrix system for complete delivery of Pioglitazone hydrochloride (HCl, in a zero-order manner over an extended time period using processed Aloe vera gel mucilage (PAG as a release modifier. Materials and Methods: The matrices were prepared by dry blending of selected ratios of polymer and ingredients using direct compression technique. Physicochemical properties of dried powdered mucilage of A. vera were studied. Various formulations of pioglitazone HCl and A. vera mucilage were prepared using different drug: Polymer ratios viz., 1:1, 1:2, 1:3, 1:4, 1:5 for PAG by direct compression technique. Results: The formulated matrix tablets were found to have better uniformity of weight and drug content with low statistical deviation. The swelling behavior and in vitro release rate characteristics were also studied. Conclusion: The study proved that the dried A. vera mucilage can be used as a matrix forming material for controlled release of Pioglitazone HCl matrix tablets.

  18. Redistribution of Income: Policy Directions

    Directory of Open Access Journals (Sweden)

    James B. Davies

    2013-08-01

    Full Text Available Poverty and rising income inequality in Canada have brought demands for improved government action on redistribution. Unfortunately, such pleas risk being overshadowed by a looming fiscal crunch as the baby boomers retire. An expanding population of seniors will add at least one percent annually to both growing health and OAS/GIS costs so that, absent meaningful change, other spending will have to be slashed by an average of 20.2 percent by 2032 if total spending and revenues are not to rise relative to GDP. For Canada’s tax-transfer system to keep fulfilling its redistributive role, a fundamental rethink is required. With non-seniors spending being squeezed, some changes in tax mix, moderate revenue increases and refined targeting of transfers will be needed to protect the system’s progressive nature. Increasing personal income tax and reducing property tax by an offsetting amount would improve redistribution without raising taxes. More revenue could be obtained without severe distortions via a capital transfer tax, the elimination of boutique credits aimed at niche beneficiaries, or perhaps a dual income tax which exacts more from labor than capital income. Improvements to existing transfer programs are another way forward. The conversion of EI to a purely insurance basis, freeing up funds to support redistribution via refundable credits is a possibility. Another cost-saver involves removing the indexation of the OAS/GIS income threshold and allowing its real value to decline, making more recipients subject to clawbacks. Whichever course governments pursue, revamping Canada’s taxtransfer system will be a delicate and difficult task. This paper explores the policy choices available, and makes it clear that time is not on our side.

  19. The releases control and the environment survey of the Cea Centers

    International Nuclear Information System (INIS)

    2002-01-01

    The Cea sets the environment protection in the heart of its security policy, which is based on the mastership of risks resulting from the researches activities and installations development. This policy aims to reduce as small as possible compared with the technical and economical necessities, the impact of its activities on the human and the environment. This document, takes stock for the year 2002, of the liquid and gas radioactive effluents releases as also of the radioactivity level around the Cea Centers, by a systematic monitoring of the atmosphere, the waters, the vegetation and the milk. (A.L.B.)

  20. A research on EU trade policy system

    Directory of Open Access Journals (Sweden)

    Qi Sitong

    2017-08-01

    Full Text Available The EU is the world’s largest trade group, occupying an important position in the world trade in goods and services, especially in the field of service trade. The EU trade in services exports and imports are higher than the United States and Japan, and the EU is the world’s largest capital output and input group, and the world’s largest foreign aid providers. With the deepening of the European integration process, Europe’s position in the world economy and trade is on the rise. Therefore, the EU’s trade policy has increasingly become the focus of attention. From the vertical point of view, research directions can be divided into trade in goods policy, trade in services policy, international direct investment policy, trade-related intellectual property policy four field. In this paper, the four vertical areas are illustrated as the focus of the study.

  1. Work load and management in the delivery room: changing the direction of healthcare policy.

    Science.gov (United States)

    Sfregola, Gianfranco; Laganà, Antonio Simone; Granese, Roberta; Sfregola, Pamela; Lopinto, Angela; Triolo, Onofrio

    2017-02-01

    Nurse staffing, increased workload and unstable nursing unit environments are linked to negative patient outcomes including falls and medication errors on medical/surgical units. Considering this evidence, the aim of our study was to overview midwives' workload and work setting. We created a questionnaire and performed an online survey. We obtained information about the type and level of hospital, workload, the use of standardised procedures, reporting of sentinel and 'near-miss' events. We reported a severe understaffing in midwives' work settings and important underuse of standard protocols according to the international guidelines, especially in the South of Italy. Based on our results, we strongly suggest a change of direction of healthcare policy, oriented to increase the number of employed midwives, in order to let them fulfil their duties according to the international guidelines (especially one-to-one care). On the other hand, we encourage the adoption of standardised protocols in each work setting.

  2. Policy Driven Development: Flexible Policy Insertion for Large Scale Systems.

    Science.gov (United States)

    Demchak, Barry; Krüger, Ingolf

    2012-07-01

    The success of a software system depends critically on how well it reflects and adapts to stakeholder requirements. Traditional development methods often frustrate stakeholders by creating long latencies between requirement articulation and system deployment, especially in large scale systems. One source of latency is the maintenance of policy decisions encoded directly into system workflows at development time, including those involving access control and feature set selection. We created the Policy Driven Development (PDD) methodology to address these development latencies by enabling the flexible injection of decision points into existing workflows at runtime , thus enabling policy composition that integrates requirements furnished by multiple, oblivious stakeholder groups. Using PDD, we designed and implemented a production cyberinfrastructure that demonstrates policy and workflow injection that quickly implements stakeholder requirements, including features not contemplated in the original system design. PDD provides a path to quickly and cost effectively evolve such applications over a long lifetime.

  3. Policy issues on the control of major accident hazards and the new Seveso II directive

    International Nuclear Information System (INIS)

    Porter, S.; Wettig, J.

    1999-01-01

    No one wants a major accident to occur! This paper describes the development of EC policies to convert this simple and obvious fact into a coherent prevention strategy which can deliver a high level of protection throughout the European Community. The Seveso II Directive is described in detail, being the relevant Community Instrument which Member States must implement in their national laws. The need to achieve the correct balance between setting general goals and being over prescriptive is discussed, commensurate with the intent to be flexible but yet consistent and effective at the same time. The main changes from Seveso I are discussed, including requirements related to the operator's management systems, the competent authority's systems for inspection, and information and consultation arrangements with the public. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

  4. Do release-site biases reflect response to the Earth's magnetic field during position determination by homing pigeons?

    Science.gov (United States)

    Mora, Cordula V; Walker, Michael M

    2009-09-22

    How homing pigeons (Columba livia) return to their loft from distant, unfamiliar sites has long been a mystery. At many release sites, untreated birds consistently vanish from view in a direction different from the home direction, a phenomenon called the release-site bias. These deviations in flight direction have been implicated in the position determination (or map) step of navigation because they may reflect local distortions in information about location that the birds obtain from the geophysical environment at the release site. Here, we performed a post hoc analysis of the relationship between vanishing bearings and local variations in magnetic intensity using previously published datasets for pigeons homing to lofts in Germany. Vanishing bearings of both experienced and naïve birds were strongly associated with magnetic intensity variations at release sites, with 90 per cent of bearings lying within +/-29 degrees of the magnetic intensity slope or contour direction. Our results (i) demonstrate that pigeons respond in an orderly manner to the local structure of the magnetic field at release sites, (ii) provide a mechanism for the occurrence of release-site biases and (iii) suggest that pigeons may derive spatial information from the magnetic field at the release site that could be used to estimate their current position relative to their loft.

  5. Navigating the science-policy spectrum: Opportunities to work on policies related to your research

    Science.gov (United States)

    Licker, R.; Ekwurzel, B.; Goldman, G. T.; DeLonge, M. S.

    2017-12-01

    Many scientists conduct research with direct policy relevance, whether it be producing sea-level projections that are taken-up by local decision-makers, or developing new agricultural technologies. All scientists are affected by policies made by their respective local, regional, and federal governments. For example, budgets affect the grant resources available to conduct research and policies on visas influence the accessibility of new positions for foreign scientists. As a result, many scientists would like to engage with the policy domain, and either bring their science to bear on new policies that are in the works (science-for-policy) or inform policies on the scientific research enterprise (policy-for-science). Some scientists prefer to engage and be neutral to the policy outcome, serving primarily as an information resource. Many may choose to also advocate for a particular outcome based on their expertise and experience. Research shows that policy decisions benefit greatly from the input of scientific experts. We explore the spectrum between informing policies in a "non-prescriptive" manner to working on policies in an advocacy space. We highlight tips for successful engagement along this spectrum. Finally, we review current science-for-policy and policy-for-science issues of relevance to the geophysical sciences.

  6. NEAMS Software Licensing, Release, and Distribution: Implications for FY2013 Work Package Planning

    International Nuclear Information System (INIS)

    Bernholdt, David E.

    2012-01-01

    The vision of the NEAMS program is to bring truly predictive modeling and simulation (M and S) capabilities to the nuclear engineering community in order to enable a new approach to the analysis of nuclear systems. NEAMS anticipates issuing in FY 2018 a full release of its computational 'Fermi Toolkit' aimed at advanced reactor and fuel cycles. The NEAMS toolkit involves extensive software development activities, some of which have already been underway for several years, however, the Advanced Modeling and Simulation Office (AMSO), which sponsors the NEAMS program, has not yet issued any official guidance regarding software licensing, release, and distribution policies. This motivated an FY12 task in the Capability Transfer work package to develop and recommend an appropriate set of policies. The current preliminary report is intended to provide awareness of issues with implications for work package planning for FY13. We anticipate a small amount of effort associated with putting into place formal licenses and contributor agreements for NEAMS software which doesn't already have them. We do not anticipate any additional effort or costs associated with software release procedures or schedules beyond those dictated by the quality expectations for the software. The largest potential costs we anticipate would be associated with the setup and maintenance of shared code repositories for development and early access to NEAMS software products. We also anticipate an opportunity, with modest associated costs, to work with the Radiation Safety Information Computational Center (RSICC) to clarify export control assessment policies for software under development.

  7. Pharmaceutical policy and the lay public

    DEFF Research Database (Denmark)

    Traulsen, Janine Marie; Almarsdóttir, Anna Birna

    2005-01-01

    Almost every national and supranational health policy document accords high importance to the need to listen to and 'empower' patients. The relationship between pharmaceutical policy and the lay public is not direct but mediated by several actors, including health care workers, patient organisati......Almost every national and supranational health policy document accords high importance to the need to listen to and 'empower' patients. The relationship between pharmaceutical policy and the lay public is not direct but mediated by several actors, including health care workers, patient...... organisations, industry and, most recently, the media. Although the overall aim of health and pharmaceutical policy is to address the needs of all citizens, there are only a few, well organised groups who are actually consulted and involved in the policymaking process, often with the support of the industry....... The reasons for this lack of citizen involvement in health and pharmaceutical policymaking are many, for example: there is no consensus about what public involvement means; there is a predominance of special interest groups with narrow, specific agendas; not all decision makers welcome lay participation...

  8. Ultrasound-assisted endoscopic partial plantar fascia release.

    Science.gov (United States)

    Ohuchi, Hiroshi; Ichikawa, Ken; Shinga, Kotaro; Hattori, Soichi; Yamada, Shin; Takahashi, Kazuhisa

    2013-01-01

    Various surgical treatment procedures for plantar fasciitis, such as open surgery, percutaneous release, and endoscopic surgery, exist. Skin trouble, nerve disturbance, infection, and persistent pain associated with prolonged recovery time are complications of open surgery. Endoscopic partial plantar fascia release offers the surgeon clear visualization of the anatomy at the surgical site. However, the primary medial portal and portal tract used for this technique have been shown to be in close proximity to the posterior tibial nerves and their branches, and there is always the risk of nerve damage by introducing the endoscope deep to the plantar fascia. By performing endoscopic partial plantar fascia release under ultrasound assistance, we could dynamically visualize the direction of the endoscope and instrument introduction, thus preventing nerve damage from inadvertent insertion deep to the fascia. Full-thickness release of the plantar fascia at the ideal position could also be confirmed under ultrasound imaging. We discuss the technique for this new procedure.

  9. Direct and indirect effects of waste management policies on household waste behaviour: The case of Sweden.

    Science.gov (United States)

    Andersson, Camilla; Stage, Jesper

    2018-03-28

    Swedish legislation makes municipalities responsible for recycling or disposing of household waste. Municipalities therefore play an important role in achieving Sweden's increased levels of ambition in the waste management area and in achieving the goal of a more circular economy. This paper studies how two municipal policy instruments - weight-based waste tariffs and special systems for the collection of food waste - affect the collected volumes of different types of waste. We find that a system of collecting food waste separately is more effective overall than imposing weight-based waste tariffs in respect not only of reducing the amounts of waste destined for incineration, but also of increasing materials recycling and biological recovery, despite the fact that the direct incentive effects of these two systems should be similar. Separate food waste collection was associated with increased recycling not only of food waste but also of other waste. Introducing separate food waste collection indirectly signals to households that recycling is important and desirable, and our results suggest that this signalling effect may be as important as direct incentive effects. Copyright © 2018. Published by Elsevier Ltd.

  10. Effect Of Ether Derivative Cellulose Polymers On Hydration, Erosion And Release Kinetics Of Diclofenac Sodium Matrix Tablets

    Directory of Open Access Journals (Sweden)

    Muhammad Akhlaq*1,2, Gul Majid Khan1 , Abdul Wahab1, Waqas Rabbani1, Abid Hussain1, Asif Nawaz1, & Alam Zeb1

    2011-09-01

    Full Text Available Objectives: The work aims to investigate the effect ofhydrophilic and hydrophobic polymers swelling and erosionon the release behaviour of DCL-Na from controlled matrixtablets prepared by direct compression and wet-granulationtechniques.Materials and Methods: Powder preformulation studies wereconducted. Tablets were prepared by direct compressiontechnique and their physicochemical properties wereevaluated. Drug-polymer interaction was analyzed by FTIRspectroscopy. The in-vitro drug release study was conductedusing phosphte buffer pH 7.4 as dissolution medium anddifferent kinetic parameters were applied.Results and Discussion: F-1 and F-5 containing ethycelluloseprepared by direct compression and wet granulationtechniques released 94 % and 84 % drug after 24hrs, while F-2and F-6 containing hydroxypropylmethylcellulose polymerprepared by direct compression and wet granulation released98.46 % and 91.25 % drug after within 24 hrs respectively.Ethylcellulose and hydroxypropylmethylcellulose based matrixtablets showed the best anomalous drug release behaviour,with the release exponents “ n ” ranging from 0.685 to 0.809.Conclusion: It has been concluded that ethylcellulose etherderivative polymer is used to prepare oral controlled releasematrix tablet of diclofenac sodium. Fickian drug diffusion,polymer hydration and erosion mechanisms occurredsimultaneously and were considered as the main drug releasecontrolling factors.

  11. Rabbit IgG directed to a synthetic C-terminal peptide of the major grass pollen allergen Lol p I inhibits human basophil histamine release induced by natural Lol p I.

    Science.gov (United States)

    van Ree, R; Aalberse, R C

    1995-03-01

    The potential role of allergen-specific IgG antibodies as 'blocking' antibodies in allergen-induced human basophil histamine release was investigated. This was studied in a model with the major grass pollen allergen Lol p I and polyclonal rabbit antisera directed against this allergen and against a synthetic peptide of its C terminus. When allergen and antibodies were allowed to preincubate, Lol p I induced histamine release was inhibited up to 85% by the antiserum against Lol p I. By omitting preincubation, and thereby more closely mimicking an in vivo situation, up to 55% inhibition was realized. This indicates that allergen-specific IgG can act as 'blocking' antibody without preincubation. Immunization of rabbits with a synthetic C-terminal peptide of Lol p I resulted in antibodies reactive with natural Lol p I. Despite their 100-fold lower avidity for Lol p I (as compared with antinatural Lol p I), these antibodies had the capacity to inhibit Lol p I induced histamine release for > 90% (up to 50% without preincubation). This indicates that it is possible to block histamine release induced by a major allergen with low-avidity IgG antibodies directed against a minor proportion of the allergen (25 amino acids). IgE antibodies from the donors studied were unreactive with this synthetic peptide, indicating that for blocking activity identical epitope specificity of IgE and IgG is not essential. This opens interesting perspectives for application of synthetic peptides in immunotherapy, distinct from their effects on T cell reactivity.

  12. Implementing Health Policy: Lessons from the Scottish Well Men's Policy Initiative.

    Science.gov (United States)

    Douglas, Flora; van Teijlingen, Edwin; Smith, Cairns; Moffat, Mandy

    2015-01-01

    Little is known about how health professionals translate national government health policy directives into action. This paper examines that process using the so-called Well Men's Services (WMS) policy initiative as a 'real world' case study. The WMS were launched by the Scottish Government to address men's health inequalities. Our analysis aimed to develop a deeper understanding of policy implementation as it naturally occurred, used an analytical framework that was developed to reflect the 'rational planning' principles health professionals are commonly encouraged to use for implementation purposes. A mixed-methods qualitative enquiry using a data archive generated during the WMS policy evaluation was used to critically analyze (post hoc) the perspectives of national policy makers, and local health and social care professionals about the: (a) 'policy problem', (b) interventions intended to address the problem, and (c) anticipated policy outcomes. This analysis revealed four key themes: (1) ambiguity regarding the policy problem and means of intervention; (2) behavioral framing of the policy problem and intervention; (3) uncertainty about the policy evidence base and outcomes, and; (4) a focus on intervention as outcome . This study found that mechanistic planning heuristics (as a means of supporting implementation) fails to grapple with the indeterminate nature of population health problems. A new approach to planning and implementing public health interventions is required that recognises the complex and political nature of health problems; the inevitability of imperfect and contested evidence regarding intervention, and, future associated uncertainties.

  13. Foreign Policy Involvement Matters: Towards an Analytical Framework Examining the Role of the Media in the Making of Foreign Policy

    Directory of Open Access Journals (Sweden)

    Kerstin Schulz

    2013-05-01

    Full Text Available Foreign policy processes have long played a minor role in the study of political communication. There is a broad consensus that the media is the central mediating actor and primary conduit between political decision-makers and the public. However, the media’s influence on foreign policy remains contingent across various processes and phases of foreign policy making; it is dynamic and multi-directional. Considering that the public sphere is essential for the legitimacy of foreign policy making, there is a demand for further research on the media’s performance in the making of foreign policy. Based on secondary research, this paper proposes an analytical framework for the systematic analysis of media–foreign policy relations by integrating foreign-policy context conditions as a research variable. The framework is based on the assumption that the role of the media varies across diverse foreign policy contexts depending on the intensity of governmental involvement in foreign affairs. The intensity is distinguished according to three dimensions: no involvement, indirect involvement and direct involvement. Finally, a case study is suggested in order to demonstrate the framework’s explanatory power: the German media coverage of Russia.

  14. 78 FR 63380 - Farm Credit Administration Board Policy Statements

    Science.gov (United States)

    2013-10-24

    ... Business of the Farm Credit Administration Board FCA-PS-65 Release of Consolidated Reporting System... FCS Building Association Management Operations Policies and Practices FCA-PS-71 Disaster Relief... the Members of Farm Credit System Institutions FCA-PS-81 Ethics, Independence, Arm's-Length Role, Ex...

  15. Transformation Directions of the Financial Policy in the Process of Stabilisation of the Ukrainian Economy

    OpenAIRE

    Petrushevska Viktoriya V.

    2013-01-01

    The goal of the article is consideration of theoretical provisions with respect to the state financial policy. The article considers the role of the financial policy in ensuring stabilisation of the Ukrainian financial system. It presents conceptual provisions regarding main goals, mechanisms and instruments of the stabilisation financial policy of the state. It develops economic indicators of its efficiency. The use of indicators of economic efficiency of the stabilisation financial policy b...

  16. Release of silver nanoparticles from outdoor facades

    International Nuclear Information System (INIS)

    Kaegi, Ralf; Sinnet, Brian; Zuleeg, Steffen; Hagendorfer, Harald; Mueller, Elisabeth; Vonbank, Roger; Boller, Markus; Burkhardt, Michael

    2010-01-01

    In this study we investigate the release of metallic silver nanoparticles (Ag-NP) from paints used for outdoor applications. A facade panel mounted on a model house was exposed to ambient weather conditions over a period of one year. The runoff volume of individual rain events was determined and the silver and titanium concentrations of 36 out of 65 runoff events were measured. Selected samples were prepared for electron microscopic analysis. A strong leaching of the Ag-NP was observed during the initial runoff events with a maximum concentration of 145 μ Ag/l. After a period of one year, more than 30% of the Ag-NP were released to the environment. Particles were mostly 2 S. - We provide direct evidence for the release of silver nanoparticles from exterior paints to the aquatic environment.

  17. Rabbit IgG directed to a synthetic C-terminal peptide of the major grass pollen allergen Lol p I inhibits human basophil histamine release induced by natural Lol p I

    NARCIS (Netherlands)

    van Ree, R.; Aalberse, R. C.

    1995-01-01

    The potential role of allergen-specific IgG antibodies as 'blocking' antibodies in allergen-induced human basophil histamine release was investigated. This was studied in a model with the major grass pollen allergen Lol p I and polyclonal rabbit antisera directed against this allergen and against a

  18. Department of Defense energy policy and research: A framework to support strategy

    International Nuclear Information System (INIS)

    Strakos, Joshua K.; Quintanilla, Jose A.; Huscroft, Joseph R.

    2016-01-01

    The Department of Defense (DOD) is the major consumer of energy within the Federal government, and it has been directed to implement cost cutting measures related to energy dependence through numerous Executive Orders and Congressional legislation. As a result, the DOD released an Energy Strategy which outlines ways to reduce energy requirements in order to meet both Presidential and Congressional mandates for energy security. With this research, we provide a historical review (1973–2014) of energy policy, legislation, and research. Additionally we identify gaps between strategy and research. The results show that DOD energy research lacks a unifying structure and guiding framework. We propose a knowledge management framework to unify and guide research efforts in direct support of the DOD Energy Strategy. - Highlights: •Unification of effort is needed to support strategic goals. •Provides the current state of DOD energy research. •Proposes a framework to guide DOD energy research. •Frames the DOD energy research context and landscape. •Promotes a unifying structure for DOD energy research.

  19. A review of low carbon fuel policies: Principles, program status and future directions

    International Nuclear Information System (INIS)

    Yeh, Sonia; Witcover, Julie; Lade, Gabriel E.; Sperling, Daniel

    2016-01-01

    A low carbon fuel standard (LCFS) is a market-based policy that specifies declining standards for the average lifecycle fuel carbon intensity (AFCI) of transportation fuels sold in a region. This paper: (i) compares transportation fuel carbon policies in terms of their economic efficiency, fuel price impacts, greenhouse gas emission reductions, and incentives for innovation; (ii) discusses key regulatory design features of LCFS policies; and (iii) provides an update on the implementation status of LCFS policies in California, the European Union, British Columbia, and Oregon. The economics literature finds that an intensity standard implicitly taxes emissions and subsidizes output. The output subsidy results in an intensity standard being inferior to a carbon tax in a first-best world, although the inefficiency can be corrected with a properly designed consumption tax (or mitigated by a properly designed carbon tax or cap-and-trade program). In California, from 2011 to 2015 the share of alternative fuels in the regulated transportation fuels pool increased by 30%, and the reported AFCI of all alternative fuels declined 21%. LCFS credit prices have varied considerably, rising to above $100/credit in the first half of 2016. LCFS programs in other jurisdictions share many features with California's, but have distinct provisions as well. - Highlights: • LCFS is a market-based policy that sets standards for carbon intensity of fuels. • We compare efficiency, price impacts, GHG emissions, and innovation of C policies. • In California, reported carbon intensity of alternative fuels declined 21% 2011–2015. • LCFS credit prices have varied considerably, rising to above $100/credit in the first half of 2016. • Other LCFS programs share many features with CA's and have distinct provisions.

  20. FAA Directives System

    Science.gov (United States)

    1992-08-26

    Consistent with the Federal Aviation Administration's mission to foster a safe, : secure, and efficient aviation system is the need for an effective and efficient : process for communitcating policy and procedures. The FAA Directives System : provide...

  1. Policies promoting Biofuels in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Holmgren, Kristina [IVL Swedish Environmental Research Inst., Goeteborg (Sweden); Chalmers Univ. of Technology, Div. of Heat and Power Technology., Goeteborg (Sweden)

    2012-07-01

    This report was written as part of a course in Environmental Economics and Policy Instruments at the University of Gothenburg. It aims at summarizing the policy instruments introduced to directly affect the production and use of biofuels in Sweden. Since Sweden is part of the EU also EU policies were included. There are additional policy instruments which affect the production and utilization of biofuels in a more indirect way that are not presented here. The economic analysis in this paper is limited and could be developed from the information presented in order to draw further conclusions on necessary changes in order to reach set targets.

  2. Renal epithelial cells can release ATP by vesicular fusion

    Directory of Open Access Journals (Sweden)

    Randi G Bjaelde

    2013-09-01

    Full Text Available Renal epithelial cells have the ability to release nucleotides as paracrine factors. In the intercalated cells of the collecting duct, ATP is released by connexin30 (cx30, which is selectively expressed in this cell type. However, ATP is released by virtually all renal epithelia and the aim of the present study was to identify possible alternative nucleotide release pathways in a renal epithelial cell model. We used MDCK (type1 cells to screen for various potential ATP release pathways. In these cells, inhibition of the vesicular H+-ATPases (bafilomycin reduced both the spontaneous and hypotonically (80%-induced nucleotide release. Interference with vesicular fusion using N-ethylamide markedly reduced the spontaneous nucleotide release, as did interference with trafficking from the endoplasmic reticulum to the Golgi apparatus (brefeldin A1 and vesicular transport (nocodazole. These findings were substantiated using a siRNA directed against SNAP-23, which significantly reduced spontaneous ATP release. Inhibition of pannexin and connexins did not affect the spontaneous ATP release in this cell type, which consists of ∼90% principal cells. TIRF-microscopy of either fluorescently-labeled ATP (MANT-ATP or quinacrine-loaded vesicles, revealed that spontaneous release of single vesicles could be promoted by either hypoosmolality (50% or ionomycin. This vesicular release decreased the overall cellular fluorescence by 5.8% and 7.6% respectively. In summary, this study supports the notion that spontaneous and induced ATP release can occur via exocytosis in renal epithelial cells.

  3. International Organisations and Transnational Education Policy

    Science.gov (United States)

    Moutsios, Stavros

    2009-01-01

    This paper focuses on the World Bank/IMF (International Monetary Fund), the OECD (Organisation for Economic Cooperation and Development) and the WTO (World Trade Organisation) as institutions of transnational policy making. They are all at present making education policies which are decisively shaping current directions and developments in…

  4. Policy entrepreneurs and strategies for change

    NARCIS (Netherlands)

    Brouwer, Stijn; Huitema, Dave

    2018-01-01

    Despite the fact that we currently witness an increasing interest in the study of the role of agency in policy dynamics, it remains in many respects a puzzle how policy change can be explained, let alone directed. This paper focusses intently on the concept, incidence, and strategic behaviour of

  5. Thermoresponsive latexes for fragrance encapsulation and release.

    Science.gov (United States)

    Popadyuk, N; Popadyuk, A; Kohut, A; Voronov, A

    2016-04-01

    To synthesize cross-linked latex particles protecting the encapsulated fragrance at ambient temperatures and facilitating the release of cargo at the temperature of the surface of the skin that varies in different regions of the body between 33.5 and 36.9°C. Poly(stearyl acrylate) (PSA), a polymer with long crystallizable alkyl side chains (undergoes order-disorder transitions at 45°C), was chosen as the main component of the polymer particles. As a result, new thermoresponsive polymer particles for fragrance encapsulation were synthesized and characterized, including assessing the performance of particles in triggered release by elevated temperature. To obtain network domains of various crystallinity, stearyl acrylate was copolymerized with dipropylene glycol acrylate caprylate (DGAC) (comonomer) in the presence of a dipropylene glycol diacrylate sebacate (cross-linker) using the miniemulsion process. Comonomers and a cross-linker were mixed directly in a fragrance during polymerization. Fragrance release was evaluated at 25, 31, 35 and 39°C to demonstrate a new material potential in personal/health care skin-related applications. Particles protect the fragrance from evaporation at 25°C. The fragrance release rate gradually increases at 31, 35 and 39°C. Two slopes were found on release plots. The first slope corresponds to a rapid fragrance release. The second slope indicates a subsequent reduction in the release rate. Crystalline-to-amorphous transition of PSA triggers the release of fragrances from cross-linked latex particles at elevated temperatures. The presence of the encapsulated fragrance, as well as the inclusion of amorphous fragments in the polymer network, reduces the particle crystallinity and enhances the release. Release profiles can be tuned by temperature and controlled by the amount of loaded fragrance and the ratio of comonomers in the feed mixture. © 2015 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

  6. International Organisations and Transnational Education Policy

    DEFF Research Database (Denmark)

    Moutsios, Stavros

    2009-01-01

    This paper focuses on the World Bank/IMF (International Monetary Fund), the OECD (Organisation for Economic Cooperation and Development) and the WTO (World Trade Organisation) as institutions of transnational policy making. They are all at present making education policies which are decisively...... shaping current directions and developments in national education systems. The paper reviews the enhanced role of these institutions in producing education policies and investigates the ideological basis as well as the processes through which these policies are made. It is argued that decisions are taken...... the transnationalisation of education policy making but also the full submission of education to the pursuits of global economy....

  7. Optimal Policy under Restricted Government Spending

    DEFF Research Database (Denmark)

    Sørensen, Anders

    2006-01-01

    Welfare ranking of policy instruments is addressed in a two-sector Ramsey model with monopoly pricing in one sector as the only distortion. When government spending is restricted, i.e. when a government is unable or unwilling to finance the required costs for implementing the optimum policy...... effectiveness canexceed the welfare loss from introducing new distortions. Moreover, it is found that the investment subsidy is gradually phased out of the welfare maximizing policy, which may be a policy combining the two subsidies, when the level of government spending is increased.Keywords: welfare ranking......, indirect and direct policy instruments, restricted government spending JEL: E61, O21, O41...

  8. Disability Policy Evaluation: Combining Logic Models and Systems Thinking

    Science.gov (United States)

    Claes, Claudia; Ferket, Neelke; Vandevelde, Stijn; Verlet, Dries; De Maeyer, Jessica

    2017-01-01

    Policy evaluation focuses on the assessment of policy-related personal, family, and societal changes or benefits that follow as a result of the interventions, services, and supports provided to those persons to whom the policy is directed. This article describes a systematic approach to policy evaluation based on an evaluation framework and an…

  9. [Modern directions of scientific and practical research of the policy of active and healthy longevity: experience and perspectives].

    Science.gov (United States)

    Golubeva, E Yu

    Modern terminology on active and healthy aging used in scientific and project activities is discussed. There have been analyzed the WHO conception on active aging, which has no precise universally agreed definition, its main determinants. The directions of scientific expertise in the major European projects INNOVAGE - assessment of potentially profitable social innovations relating to the welfare and quality of life and health in old age; MOPACT - the interference between the demographic development and the main dimensions of economic and social contribution of older persons is defined. The approach to implement the policy of active and healthy longevity as a valuable asset of the modern society is underlined.

  10. Tailored sequential drug release from bilayered calcium sulfate composites

    International Nuclear Information System (INIS)

    Orellana, Bryan R.; Puleo, David A.

    2014-01-01

    The current standard for treating infected bony defects, such as those caused by periodontal disease, requires multiple time-consuming steps and often multiple procedures to fight the infection and recover lost tissue. Releasing an antibiotic followed by an osteogenic agent from a synthetic bone graft substitute could allow for a streamlined treatment, reducing the need for multiple surgeries and thereby shortening recovery time. Tailorable bilayered calcium sulfate (CS) bone graft substitutes were developed with the ability to sequentially release multiple therapeutic agents. Bilayered composite samples having a shell and core geometry were fabricated with varying amounts (1 or 10 wt.%) of metronidazole-loaded poly(lactic-co-glycolic acid) (PLGA) particles embedded in the shell and simvastatin directly loaded into either the shell, core, or both. Microcomputed tomography showed the overall layered geometry as well as the uniform distribution of PLGA within the shells. Dissolution studies demonstrated that the amount of PLGA particles (i.e., 1 vs. 10 wt.%) had a small but significant effect on the erosion rate (3% vs. 3.4%/d). Mechanical testing determined that introducing a layered geometry had a significant effect on the compressive strength, with an average reduction of 35%, but properties were comparable to those of mandibular trabecular bone. Sustained release of simvastatin directly loaded into CS demonstrated that changing the shell to core volume ratio dictates the duration of drug release from each layer. When loaded together in the shell or in separate layers, sequential release of metronidazole and simvastatin was achieved. By introducing a tunable, layered geometry capable of releasing multiple drugs, CS-based bone graft substitutes could be tailored in order to help streamline the multiple steps needed to regenerate tissue in infected defects. - Highlights: • Bilayered CS composites were fabricated as potential bone graft substitutes. • The shell

  11. Tailored sequential drug release from bilayered calcium sulfate composites

    Energy Technology Data Exchange (ETDEWEB)

    Orellana, Bryan R.; Puleo, David A., E-mail: puleo@uky.edu

    2014-10-01

    The current standard for treating infected bony defects, such as those caused by periodontal disease, requires multiple time-consuming steps and often multiple procedures to fight the infection and recover lost tissue. Releasing an antibiotic followed by an osteogenic agent from a synthetic bone graft substitute could allow for a streamlined treatment, reducing the need for multiple surgeries and thereby shortening recovery time. Tailorable bilayered calcium sulfate (CS) bone graft substitutes were developed with the ability to sequentially release multiple therapeutic agents. Bilayered composite samples having a shell and core geometry were fabricated with varying amounts (1 or 10 wt.%) of metronidazole-loaded poly(lactic-co-glycolic acid) (PLGA) particles embedded in the shell and simvastatin directly loaded into either the shell, core, or both. Microcomputed tomography showed the overall layered geometry as well as the uniform distribution of PLGA within the shells. Dissolution studies demonstrated that the amount of PLGA particles (i.e., 1 vs. 10 wt.%) had a small but significant effect on the erosion rate (3% vs. 3.4%/d). Mechanical testing determined that introducing a layered geometry had a significant effect on the compressive strength, with an average reduction of 35%, but properties were comparable to those of mandibular trabecular bone. Sustained release of simvastatin directly loaded into CS demonstrated that changing the shell to core volume ratio dictates the duration of drug release from each layer. When loaded together in the shell or in separate layers, sequential release of metronidazole and simvastatin was achieved. By introducing a tunable, layered geometry capable of releasing multiple drugs, CS-based bone graft substitutes could be tailored in order to help streamline the multiple steps needed to regenerate tissue in infected defects. - Highlights: • Bilayered CS composites were fabricated as potential bone graft substitutes. • The shell

  12. Building sustainable policy framework for transport development: A review of national transport policy initiatives in Nigeria

    Directory of Open Access Journals (Sweden)

    Sumaila A.F.

    2013-06-01

    Full Text Available This paper is concerned with building a sustainable policy framework for transport development in Nigeria. Its objective is to review the country’s transport policy initiatives in order to understand the extent to which it addresses Nigeria’s mobility and transportation problems. From published materials and official government documents and files, the study identifies four national policy initiatives which are reviewed and analysed with regard to their context, contents, and consequences. The study reveals that while the policy initiatives could be said to be adequate and comprehensive in terms of their context and contents, the major challenge is implementation of recommended solutions. The study therefore provides a general checklist to guide policy direction, while advocating for policy-based researches and empirical studies in order to provide the data base for formulation of a sustainable national transport policy for Nigeria.

  13. New directions in US development policies: A view from Washington ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-04-15

    Apr 15, 2011 ... Development expert Todd Moss analyzes these trends in US development policy and forecasts what changes to expect. He also relates these trends to Canada – facing some similar issues – including how the challenges will affect the way the two countries cooperate on development. Listen to the audio ...

  14. Solar energy policy review

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-08-17

    A number of memoranda and reports are collected which deal with evaluations of solar energy policy options, including direct and indirect labor impacts and costs of different options and consumer protection. (LEW)

  15. Tritium release from neutron irradiated beryllium pebbles

    Energy Technology Data Exchange (ETDEWEB)

    Scaffidi-Argentina, F.; Werle, H. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Inst. fuer Neutronenphysik und Reactortechnik

    1998-01-01

    One of the most important open issues related to beryllium for fusion applications refers to the kinetics of the tritium release as a function of neutron fluence and temperature. The EXOTIC-7 as well as the `Beryllium` experiments carried out in the HFR reactor in Petten are considered as the most detailed and significant tests for investigating the beryllium response under neutron irradiation. This paper reviews the present status of beryllium post-irradiation examinations performed at the Forschungszentrum Karlsruhe with samples from the above mentioned irradiation experiments, trying to elucidate the tritium release controlling processes. In agreement with previous studies it has been found that release starts at about 500-550degC and achieves a maximum at about 700-750degC. The observed release at about 500-550degC is probably due to tritium escaping from chemical traps, while the maximum release at about 700-750degC is due to tritium escaping from physical traps. The consequences of a direct contact between beryllium and ceramics during irradiation, causing tritium implanting in a surface layer of beryllium up to a depth of about 40 mm and leading to an additional inventory which is usually several times larger than the neutron-produced one, are also presented and the effects on the tritium release are discussed. (author)

  16. US energy policy

    International Nuclear Information System (INIS)

    Katz, J.E.

    1984-01-01

    After three years in power, the Reagan Administration has been able to reverse much of the US federal government's energy policy measures that had occurred since 1973, particularly the build-up that took place during the Carter presidency. Another change is a repudiation of social equity concerns, which were an important part of the energy policies of the Nixon, Ford and Carter presidencies. Instead of using government to direct energy policy, the Reagan Administration has stressed the pre-eminence of the private sector. One exception is nuclear energy, which the Administration strongly supports. While the Reagan policies implemented have increased economic efficiency and reduced federal-related budgets and staffs, they have caused environmental degradation and hardship on the poor. Yet their greatest implication is that of a nation less well prepared to handle a severe energy shortage. The Administration believes this is not a problem, based on its optimistic expectations of the extent of untapped resources worldwide and the resilience of the free market. (author)

  17. Role of various natural, synthetic and semi-synthetic polymers on drug release kinetics of losartan potassium oral controlled release tablets.

    Science.gov (United States)

    Jayasree, J; Sivaneswari, S; Hemalatha, G; Preethi, N; Mounika, B; Murthy, S Vasudeva

    2014-10-01

    The objective of the present work was to formulate and to characterize controlled release matrix tablets of losartan potassium in order to improve bioavailability and to minimize the frequency of administration and increase the patient compliance. Losartan potassium controlled release matrix tablets were prepared by direct compression technique by the use of different natural, synthetic and semisynthetic polymers such as gum copal, gum acacia, hydroxypropyl methyl cellulose K100 (HPMC K100), eudragit RL 100 and carboxy methyl ethyl cellulose (CMEC) individually and also in combination. Studies were carried out to study the influence of type of polymer on drug release rate. All the formulations were subjected to physiochemical characterization such as weight variation, hardness, thickness, friability, drug content, and swelling index. In vitro dissolution studies were carried out simulated gastric fluid (pH 1.2) for first 2 h and followed by simulated intestinal fluid (pH 6.8) up to 24 h, and obtained dissolution data were fitted to in vitro release kinetic equations in order to know the order of kinetics and mechanism of drug release. Results of physiochemical characterization of losartan potassium matrix tablets were within acceptable limits. Formulation containing HPMC K100 and CMEC achieved the desired drug release profile up to 24 h followed zero order kinetics, release pattern dominated by Korsmeyer - Peppas model and mechanism of drug release by nonfickian diffusion. The good correlation obtained from Hixson-Crowell model indicates that changes in surface area of the tablet also influences the drug release. Based on the results, losartan potassium controlled release matrix tablets prepared by employing HPMC K100 and CMEC can attain the desired drug release up to 24 h, which results in maintaining steady state concentration and improving bioavailability.

  18. Excessive nickel release from mobile phones--a persistent cause of nickel allergy and dermatitis.

    Science.gov (United States)

    Jensen, Peter; Johansen, Jeanne D; Zachariae, Claus; Menné, Torkil; Thyssen, Jacob P

    2011-12-01

    Despite the political intention to limit nickel allergy and dermatitis in Europeans, nickel allergy remains frequent. There are several explanations for the persistence of nickel allergy and dermatitis, including the increasing use of mobile phones. Before regulation of nickel release from mobile phones, we showed that eight (19.5%) of 41 mobile phones marketed in Denmark between 2003 and 2007 released nickel in concentrations that may result in nickel allergy and dermatitis. In 2009, the EU Nickel Directive was revised to include nickel-releasing mobile phones. To investigate the proportion of mobile phones sold in Denmark that release nickel after regulation. Metallic parts from 50 randomly selected mobile phones currently for sale in Denmark were tested for nickel release by use of the dimethylglyoxime (DMG)-nickel spot test. Nine (18%) phones showed at least one positive DMG test reaction and two phones had more than one DMG test-positive spot. Apparently, the proportion of mobile phones with significant nickel release remains unchanged, despite the 2009 revision of the EU Nickel Directive. We encourage manufacturers to measure nickel release from metallic components used in the assembly of mobile phones to ensure safe products. © 2011 John Wiley & Sons A/S.

  19. Sustained release of BMP-2 in bioprinted alginate for osteogenicity in mice and rats.

    Directory of Open Access Journals (Sweden)

    Michelle T Poldervaart

    Full Text Available The design of bioactive three-dimensional (3D scaffolds is a major focus in bone tissue engineering. Incorporation of growth factors into bioprinted scaffolds offers many new possibilities regarding both biological and architectural properties of the scaffolds. This study investigates whether the sustained release of bone morphogenetic protein 2 (BMP-2 influences osteogenicity of tissue engineered bioprinted constructs. BMP-2 loaded on gelatin microparticles (GMPs was used as a sustained release system, which was dispersed in hydrogel-based constructs and compared to direct inclusion of BMP-2 in alginate or control GMPs. The constructs were supplemented with goat multipotent stromal cells (gMSCs and biphasic calcium phosphate to study osteogenic differentiation and bone formation respectively. BMP-2 release kinetics and bioactivity showed continuous release for three weeks coinciding with osteogenicity. Osteogenic differentiation and bone formation of bioprinted GMP containing constructs were investigated after subcutaneous implantation in mice or rats. BMP-2 significantly increased bone formation, which was not influenced by the release timing. We showed that 3D printing of controlled release particles is feasible and that the released BMP-2 directs osteogenic differentiation in vitro and in vivo.

  20. Impact of Industrial Releases on Inshas Area

    International Nuclear Information System (INIS)

    El-Messiry, A.M.; Aly, M.M.

    1999-01-01

    Two Egyptian research reactors are located within the nuclear research center at Inshas area, 30 km north east of Cairo. This area are crowded by different industrial plants. The releases from them has a hazardous and economical effects on the research center workers and the surrounding inhabitancy. In the present work we study these effects. A meteorological regional specific data is considered all over the year, including a wind rose characterization. The study considered both normal operating conditions and an accidental releases. The results shows that there are a considerable risk due to normal releases in some areas downwind direction of the major releases, and a highly risk in areas subjected to major exposure. Regional maps of emission distribution, economical damage , pollutant concentration are obtained. The study helps to identify solutions to problems of atmospheric protection. It can be used as a decision support for the environmental, economic, and innovation planning at the national levels taking into consideration the national pollution standards and variety of existing emission sources

  1. Competition Policy in Malaysia

    OpenAIRE

    Lee, Cassey

    2004-01-01

    Malaysia does not have a national competition law. Competition is regulated at the sectoral level in the country. Two economic sectors have legal provisions for competition law but these have been relatively ineffectively enforced. The benefits of Malaysia's industrial policy as well as the policy reforms in regulation and trade have been compromised by the lack of a formal institution to address competition related issues. Hence, the future priority and direction of regulatory reform is obvi...

  2. Monetary Policy Analysis in Serbia

    Directory of Open Access Journals (Sweden)

    Martin Vesna

    2015-09-01

    Full Text Available The paper focuses on analysing monetary policy in Serbia. The National Bank of Serbia chose inflation targeting, which sets price stability as the main objective of monetary policy. To achieve this goal, the central bank uses different monetary policy instruments which analysis can provide us with the understanding of the main directions of their actions but also of the limitations of its application. Only through improvement of both instruments and monetary policy the central bank will create a better foundation for achieving monetary stability. In addition, the implementation of exchange rate policy is entrusted to the National Bank of Serbia, as the main regulator of the financial system. A mere use of managed floating exchange rate, as the chosen exchange rate regime, is an appropriate solution in the current economic circumstances and in accordance with the desired objective of monetary policy.

  3. Models for environmental impact assessments of releases of radioactive substances from CERN facilities

    CERN Document Server

    Vojtyla, P

    2005-01-01

    The document describes generic models for environmental impact assessments of releases of radioactive substances from CERN facilities. Except for few models developed in the Safety Commission, the models are based on the 1997 Swiss directive HSK-R-41 and on the 2001 IAEA Safety Report No. 19. The writing style is descriptive, facilitating the practical implementation of the models at CERN. There are four scenarios assumed for airborne releases: (1) short-term releases for release limit calculations, (2) actual short-term releases, (3) short-term releases during incidents/accidents, and (4) chronic long-term releases during the normal operation of a facility. For water releases, two scenarios are considered: (1) a release into a river, and (2) a release into a water treatment plant. The document shall be understood as a reference for specific environmental studies involving radioactive releases and as a recommendation of the Safety Commission.

  4. Understanding the direct involvement of parents in policy development and school activities in a primary school

    Directory of Open Access Journals (Sweden)

    Tobin Bernie

    2017-12-01

    Full Text Available It is acknowledged that parental engagement with children’s learning and education is of vital importance. But, there is a tendency to confuse engagement with learning with engagement with the school. While all types of parents’ involvement can have a positive effect, it is actually what parents do with their child at home that has the greatest impact. However, unless parental involvement in learning is embedded in whole-school processes it is unlikely to as effective as possible. This paper documents an action research study that explores the inclusion of parents and home values in the construction of the teaching and learning environment. This was a small step towards positive parent-teacher collaboration, which allowed an exchange of knowledge, values and cultural background experiences. In acknowledging the ways in which the parents already engaged with their children’s learning, it began to enhance self-efficacy in their ability to directly affect this learning. This work has also provoked reflexive engagement of my influence and understanding of involving parents of children with additional and diverse learning needs. But, it also details the transformative journey that influenced my thinking about how we as a school could begin to develop whole-school processes to directly involve parents in policy development and school activities.

  5. Employment Policies in an Aging Society: Review of the Experiences of the OECD Countries with Population Aging and Their Policy Responses

    Directory of Open Access Journals (Sweden)

    Dong-Heon Kim

    2005-06-01

    Full Text Available In this paper we review the experiences of OECD countries with population aging and their policy responses, and suggest directions and measures of medium and long-term employment policies to cope with population aging in a comprehensive perspective. Specifically, following the policy objective of sustainable economic growth, we systematically classify policy types to cope with population aging and review possibilities and limitations of each policy type, while also considering Korea-specific situations as well as the experiences of other OECD countries. There are two broad types of employment policies to sustain economic growth in an aging society. One is to increase the quantity of labor force and the other is to enhance the quality of labor force. Policies to increase the quantity of labor force include pro-natalist policies, immigration policies, and policies to fully mobilize the labor resources of women and older people. Policies to enhance the quality of labor force include human resource development and flexicurity policies in the labor market. Our review suggests that direct pro-natalist policies seem to be ineffective. Also immigration policies cannot fundamentally solve the problem caused by population aging. Policies to fully mobilize the labor resources of women and older people seem to be the most effective policy. However, labor productivity should be an engine of economic growth in the long run when labor input reaches the limit of its capacity. In conclusion, in the long run, it is most important to enhance the quality of human capital and improve the functioning of the labor market to cope with the challenges of population aging.

  6. Fluoride and sodium trimetaphosphate (TMP release from fluoride varnishes supplemented with TMP

    Directory of Open Access Journals (Sweden)

    Michele Mauricio MANARELLI

    2016-01-01

    Full Text Available Abstract This study assessed fluoride (F and sodium trimetaphosphate (TMP release into artificial saliva from varnishes containing 0%, 2.5%, and 5% NaF, supplemented or not with 5% TMP. The varnishes were applied on polyester sheets (n = 8/group, and F and TMP released into artificial saliva were measured for up to 24 hours. The amount of F and TMP released were directly related to NaF and TMP concentrations in the varnishes. The highest F release was seen for 5% NaF and 5% NaF + 5% TMP, whereas 5% TMP released the highest amount of TMP. However, the simultaneous addition of NaF and TMP to varnishes significantly reduced the amount of F and TMP released from the products.

  7. Altered elementary calcium release events and enhanced calcium release by thymol in rat skeletal muscle.

    Science.gov (United States)

    Szentesi, Péter; Szappanos, Henrietta; Szegedi, Csaba; Gönczi, Monika; Jona, István; Cseri, Julianna; Kovács, László; Csernoch, László

    2004-03-01

    The effects of thymol on steps of excitation-contraction coupling were studied on fast-twitch muscles of rodents. Thymol was found to increase the depolarization-induced release of calcium from the sarcoplasmic reticulum, which could not be attributed to a decreased calcium-dependent inactivation of calcium release channels/ryanodine receptors or altered intramembrane charge movement, but rather to a more efficient coupling of depolarization to channel opening. Thymol increased ryanodine binding to heavy sarcoplasmic reticulum vesicles, with a half-activating concentration of 144 micro M and a Hill coefficient of 1.89, and the open probability of the isolated and reconstituted ryanodine receptors, from 0.09 +/- 0.03 to 0.22 +/- 0.04 at 30 micro M. At higher concentrations the drug induced long-lasting open events on a full conducting state. Elementary calcium release events imaged using laser scanning confocal microscopy in the line-scan mode were reduced in size, 0.92 +/- 0.01 vs. 0.70 +/- 0.01, but increased in duration, 56 +/- 1 vs. 79 +/- 1 ms, by 30 micro M thymol, with an increase in the relative proportion of lone embers. Higher concentrations favored long events, resembling embers in control, with duration often exceeding 500 ms. These findings provide direct experimental evidence that the opening of a single release channel will generate an ember, rather than a spark, in mammalian skeletal muscle.

  8. Percutaneous carpal tunnel release compared with mini-open release using ultrasonographic guidance for both techniques.

    Science.gov (United States)

    Nakamichi, Ken-ichi; Tachibana, Shintaro; Yamamoto, Seizo; Ida, Masayoshi

    2010-03-01

    To compare the outcomes of percutaneous carpal tunnel release (PCTR) and mini-open carpal tunnel release (mini-OCTR) using ultrasonographic guidance for both techniques. We included 74 hands of 65 women with idiopathic carpal tunnel syndrome (age, 52-71 y; mean, 58 y). Thirty-five hands of 29 women had the PCTR (release with a device consisting of an angled blade, guide, and holder, along a line midway between the median nerve and ulnar artery (safe line) under ultrasonography (incision, 4 mm), and 39 hands of 36 women had the mini-OCTR (release along the safe line, distally under direct vision (incision, 1-1.5 cm) and proximally under ultrasonography, using a device consisting of a basket punch and outer tube. Assessments at 3, 6, 13, 26, 52, and 104 weeks showed no significant differences in neurologic recovery between the groups (p > .05). The PCTR group had significantly less pain, greater grip and key-pinch strengths, and better satisfaction scores at 3 and 6 weeks (p < .05), and less scar sensitivity at 3, 6, and 13 weeks (p < .05). There were no complications. The PCTR provides the same neurologic recovery as does the mini-OCTR. The former leads to less postoperative morbidity and earlier functional return and achievement of satisfaction. Therapeutic III. Copyright 2010. Published by Elsevier Inc.

  9. Electrochemically controlled release of anticancer drug methotrexate using nanostructured polypyrrole modified with cetylpyridinium: Release kinetics investigation

    International Nuclear Information System (INIS)

    Alizadeh, Naader; Shamaeli, Ehsan

    2014-01-01

    A new simple strategy for direct electrochemical incorporation of chemotherapeutic methotrexate (MTX) into conductive polypyrrole (PPy) has been suggested for an electrochemically controlled loading and release system. Electropolymerization of MTX doped polypyrrole yielded poor quality with low efficiency of doping, but a well-doped, nanostructure and increased capacity of drug loading (24.5 mg g −1 ) has been obtained in the presence of cetylpyridinium (CP) as a modifier. When CP was preloaded onto PPy, the hydrophobic surface of the PPy serves as a backbone to which the hydrophobic chain of the CP can be attached. Electrostatic interaction between cationic CP with anionic MTX and aromatic interaction between pyridinium head of CP with pyrimidine and pyrazine rings of MTX increases drug doping. Then release kinetics were investigated at various applied potentials and temperatures. Kinetics analysis based on Avrami's equation showed that the drug release was controlled and accelerated by increasing temperature and negative potential and sustained by increasing positive potential. At open circuit condition, the release parameter (n) represented a diffusive mechanism and at applying electrochemical potentials, a first-order mode. Activation energy parameters (E a , ΔG ≠ , ΔH ≠ and ΔS ≠ ) and half-life time (t 1/2 ) of drug release are also analyzed as a function of applied potential. The nanostructured polymer films (PPy/CP/MTX) were characterized by several techniques: scanning electron microscopy, Furrier transforms Infrared, UV-vis spectroscopy. Overall, our results demonstrate that the PPy/CP/MTX films, combined with electrical stimulation, permit a programmable release of MTX by altering the interaction strength between the PPy/CP and MTX

  10. Framing the Framework: Discourses in Australia's National Values Education Policy

    Science.gov (United States)

    Jones, Tiffany Mary

    2009-01-01

    In the past, many Australian state schools avoided teaching about values explicitly. However, the Australian government released Australia's first official values education policy in 2005: the "National Framework for Values Education in Australian Schools" (NFVEAS). This framework represents a local manifestation of the recent…

  11. Towards a systematic framework for the analysis of environmental policy Integration

    NARCIS (Netherlands)

    Runhaar, Hens; Driessen, Peter; Uittenbroek, Caroline

    Environmental policy integration (EPI) refers to the incorporation of environmental concerns in non-environmental policy sectors. EPI aims to avoid conflicts between environmental and other policy objectives and to enhance environmental policy by directly targeting the driving forces of

  12. Road safety policy of the European Union.

    NARCIS (Netherlands)

    2013-01-01

    The European Union (EU) is important for national road safety policies. The EU has several policymaking instruments, such as binding regulations and directives, and non-binding recommendations. An important element in the EU policy plans on road safety are the non-binding European road safety

  13. Alcohol Control and Harm Reduction Policies in Lebanon | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Findings will document the current national alcohol policy and identify the direct and indirect influences of policy-relevant factors and psychosocial mediators on alcohol consumption and purchasing. Researchers will also assess the potential impact of specific alcohol-control policy packages. The results should help to ...

  14. Controlled release of tetracycline-HCl from halloysite-polymer composite films.

    Science.gov (United States)

    Ward, Christopher J; Song, Shang; Davis, Edward W

    2010-10-01

    The first direct comparison between two common methods for loading halloysite with a small molecule for controlled release is presented. While the methods differ in the degree of simplicity, they provide essentially the same level of loading and release kinetics. A tentative explanation of the "burst" effect often seen in the release of low molecular weight molecules from halloysite is provided. The ability of halloysite to mediate the release rate of a water soluble drug, tetracycline, from solution cast polyvinyl alcohol and polymethyl methacrylate films was evaluated. In some films, montmorillonite was also incorporated. The addition of montmorillonite to solutions used to cast tetracycline containing films significantly reduced the release rate from the dried films. The same overall effect was seen when the drug was loaded into halloysite prior to preparation of the films. In both cases, the release was best fit with the simple Higuchi model. However, when montmorillonite was added to solutions of polyvinyl alcohol and drug loaded halloysite the release profiles were better fit by the Ritgar-Peppas model for anomalous transport. Release from polymethyl methacrylate was reduced by a factor of three by incorporating the drug in halloysite prior to producing the films.

  15. International Organisations and Transnational Education Policy

    DEFF Research Database (Denmark)

    Moutsios, Stavros

    2009-01-01

    This paper focuses on the World Bank/IMF (International Monetary Fund), the OECD (Organisation for Economic Cooperation and Development) and the WTO (World Trade Organisation) as institutions of transnational policy making. They are all at present making education policies which are decisively...... shaping current directions and developments in national education systems. The paper reviews the enhanced role of these institutions in producing education policies and investigates the ideological basis as well as the processes through which these policies are made. It is argued that decisions are taken...... largely through asymmetric, non-democratic and opaque procedures. It is also argued that the proposed policies purport to serve the principles of relentless economic competition. Taking into account similar policies and initiatives, the paper concludes that we are experiencing not only...

  16. The future of European health policies.

    Science.gov (United States)

    Koivusalo, Meri Tuulikki

    2005-01-01

    The role of the European Union in health policies is changing. The European social model is under threat due to shifts in E.U. policies on liberalization of service provision, limited public budgets, a focus on the health sector as a productive sector in the context of broader European policies and the Lisbon strategy, and changes in the context of the new Constitutional Treaty. These changes are evident in a new reflection paper on European health strategy and its focus. E.U. health policies are at a critical juncture. The danger is that the current processes will lead European health policies and the health systems of member states more in the direction of U.S. health policies and the commercialization of health systems than toward improvement of the current situation.

  17. Exchange Rate Policy in Philippine Development

    OpenAIRE

    Bautista, Romeo M.

    2003-01-01

    This paper examines the conduct of exchange rate policy in the Philippines since the early 1980s, paying particular attention to the influence of exchange rate adjustments on relative production incentives. While primary interest is in the exchange rate regime and its incentive effects, the role of trade policy has to be simultaneously analyzed in view of its influence on the conduct of exchange rate policy as well as its direct effect on the real exchange rate. Moreover, there are analytical...

  18. NRC Enforcement Policy Review, July 1995-July 1997

    International Nuclear Information System (INIS)

    Lieberman, J.; Pedersen, R.M.

    1998-04-01

    On June 30, 1995, the Nuclear Regulatory Commission (NRC) issued a complete revision of its General Statement of Policy and Procedure for Enforcement Action (Enforcement Policy) (60 FR 34381). In approving the 1995 revision to the Enforcement Policy, the Commission directed the staff to perform a review of its implementation of the Policy after approximately 2 years of experience and to consider public comments. This report represents the results of that review

  19. BUDGETARY REGIONAL POLICY: THEORETICAL CONCEPTUALIZATION

    Directory of Open Access Journals (Sweden)

    Shyshpanova Nataliia

    2018-01-01

    Full Text Available Introduction. Formation and implementation of the budget policy of the regions in Ukraine is directly related to the processes of decentralization of power, increase of budget powers and strengthening of financial capacity of the territories. Formation of balanced local budgets and support of an effective system of managing budget resources is a key to strengthening the economic potential of the regions and increasing the well-being of citizens. The purpose of this article is to assess the current concepts of the fiscal policy of the region in Ukraine and to determine the impact of fiscal policy on the socio-economic development of the regions. Results. In this article the essence and content of budget policy are considered, the interpretation of different scientists is presented. An author’s approach to the definition of the essence of the budget policy of the region as a set of economic and administrative measures in the budget sphere, determined by the interrelated goals and objectives of the state and local self-government, aimed at the socio-economic development of the territory. The conceptual model of the fiscal policy of the region is presented and it is determined that the strategic goal of fiscal policy at the local level should be to ensure sustainable socio-economic development of the territories. The main principles that need to be observed during the implementation of the budget policy of the region are described; functions to be performed by local level fiscal policy; and the main tools by which local authorities carry out their functions. Conclusions. It is noted that the content of the budget policy of the region should be to determine the course, tasks and directions of the state and local self-government activities in the field of the formation and use of budget funds. The budget policy of the region should respond to a combination of the following systemic challenges: 1. the restoration of economic growth, as soon as

  20. Direction and Policies Needed to Support Hybrid Electric Car Research

    Directory of Open Access Journals (Sweden)

    Ridwan Arief Subekti

    2012-07-01

    Full Text Available The rising number of vehicles over the years has driven the increase of air pollution and fuel consumption. One of the solutions to overcome this problem is using hybrid electric car because it is environmentally friendly and efficient in fuel consumption. LIPI has conducted electric car research since 1997, but there were so many problems in its development that electric car can not be developed into a national industry scale. Therefore, it is important to conduct a study that maps the problems and finds the solutions to prevent the same failure of electric car commercialization process from happening to hybrid electric car . This study was done by collecting and analyzing the primary and secondary data through interviews, discussing electric hybrid car with stakeholders, and examining earlier study results and regulations. Based on this study, several policies to support sustainability research of hybrid electric car were proposed. Some recommendations were the making of national roadmap and regulation for the usage of hybrid electric car on the road. For policy makers at LIPI, a research focus, research coordination, and pre-commercialization program were recommended.

  1. Australian television news coverage of alcohol, health and related policies, 2005 to 2010: implications for alcohol policy advocates.

    Science.gov (United States)

    Fogarty, Andrea S; Chapman, Simon

    2012-12-01

    To describe television news coverage between 2005 and 2010 of alcohol, health and relevant alcohol-control policies, with a view to informing policy advocacy. A content analysis of all alcohol stories archived by the Australian Health News Research Collaboration. We recorded what triggered a news item, the main topics covered, whether risks to health were communicated, whether alcohol-control policies were featured and which news-actors appeared. We identified 612 stories, where 69.2% were triggered by a particular newsworthy incident or the release of new findings. The most frequently reported alcohol stories were focused on associated harms (30.2%) and 'binge drinking' (19.0%). A majority (75.3%) reported a variety of positive and negative health effects, yet mainly focused on short-term consequences. Combined, 63% mentioned an alcohol-control policy, yet no one particular policy was featured in more than 10% of all stories. The most commonly featured news-actors included public-health professionals (50.0%), members of affected communities (28.4%) and government representatives (24.3%) Problems related to alcohol were well-established foci of news attention and reportage and covered a broad spectrum of issues related to public health goals, yet less coverage centred on long-term health consequences or effective policy solutions. Future policy advocacy could focus on moving the debate away from simple problem definition to better communication of long-term health risks, existing policies, and evidence of their effectiveness and arguments for their adoption. Future research might consider audience understanding of the information. © 2012 The Authors. ANZJPH © 2012 Public Health Association of Australia.

  2. An exploration of potential directions for climate change policy in Northern Canada

    International Nuclear Information System (INIS)

    Newton, J.; Burton, I.

    2001-01-01

    Despite the relatively small contribution to greenhouse gas emissions by residents of Northern Canada, scientists project changes in average annual temperatures in the North to be among the highest in the world. For this reason it is important to understand what may happen, as well as actions of a precautionary nature that can be taken now, and what action are likely to be required in the longer term. While focusing on climate change policy options and implementation measures for Northern Canada, the paper also discusses basic policy considerations as well as the global context that influences the national frameworks and local initiatives. 14 refs., 2 tabs., 1 fig

  3. Specialists' meeting on fission product release and transport in gas-cooled reactors. Summary report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1985-07-01

    The purpose of the Meeting on Fission Product Release and Transport in Gas-Cooled Reactors was to compare and discuss experimental and theoretical results of fission product behaviour in gas-cooled reactors under normal and accidental conditions and to give direction for future development. The technical part of the meeting covered operational experience and laboratory research, activity release, and behaviour of released activity.

  4. Specialists' meeting on fission product release and transport in gas-cooled reactors. Summary report

    International Nuclear Information System (INIS)

    1985-01-01

    The purpose of the Meeting on Fission Product Release and Transport in Gas-Cooled Reactors was to compare and discuss experimental and theoretical results of fission product behaviour in gas-cooled reactors under normal and accidental conditions and to give direction for future development. The technical part of the meeting covered operational experience and laboratory research, activity release, and behaviour of released activity

  5. Barrier and operational risk analysis of hydrocarbon releases (BORA-Release)

    International Nuclear Information System (INIS)

    Sklet, Snorre; Vinnem, Jan Erik; Aven, Terje

    2006-01-01

    This paper presents results from a case study carried out on an offshore oil and gas production platform with the purpose to apply and test BORA-Release, a method for barrier and operational risk analysis of hydrocarbon releases. A description of the BORA-Release method is given in Part I of the paper. BORA-Release is applied to express the platform specific hydrocarbon release frequencies for three release scenarios for selected systems and activities on the platform. The case study demonstrated that the BORA-Release method is a useful tool for analysing the effect on the release frequency of safety barriers introduced to prevent hydrocarbon releases, and to study the effect on the barrier performance of platform specific conditions of technical, human, operational, and organisational risk influencing factors (RIFs). BORA-Release may also be used to analyse the effect on the release frequency of risk reducing measures

  6. Activated human neutrophils release hepatocyte growth factor/scatter factor.

    LENUS (Irish Health Repository)

    McCourt, M

    2012-02-03

    BACKGROUND: Hepatocyte growth factor or scatter factor (HGF\\/SF) is a pleiotropic cytokine that has potent angiogenic properties. We have previously demonstrated that neutrophils (PMN) are directly angiogenic by releasing vascular endothelial growth factor (VEGF). We hypothesized that the acute inflammatory response can stimulate PMN to release HGF. AIMS: To examine the effects of inflammatory mediators on PMN HGF release and the effect of recombinant human HGF (rhHGF) on PMN adhesion receptor expression and PMN VEGF release. METHODS: In the first experiment, PMN were isolated from healthy volunteers and stimulated with tumour necrosis factor-alpha (TNF-alpha), lipopolysaccharide (LPS), interleukin-8 (IL-8), and formyl methionyl-leucyl-phenylalanine (fMLP). Culture supernatants were assayed for HGF using ELISA. In the second experiment, PMN were lysed to measure total HGF release and HGF expression in the PMN was detected by Western immunoblotting. Finally, PMN were stimulated with rhHGF. PMN CD 11a, CD 11b, and CD 18 receptor expression and VEGF release was measured using flow cytometry and ELISA respectively. RESULTS: TNF-alpha, LPS and fMLP stimulation resulted in significantly increased release of PMN HGF (755+\\/-216, 484+\\/-221 and 565+\\/-278 pg\\/ml, respectively) compared to controls (118+\\/-42 pg\\/ml). IL-8 had no effect. Total HGF release following cell lysis and Western blot suggests that HGF is released from intracellular stores. Recombinant human HGF did not alter PMN adhesion receptor expression and had no effect on PMN VEGF release. CONCLUSIONS: This study demonstrates that pro-inflammatory mediators can stimulate HGF release from a PMN intracellular store and that activated PMN in addition to secreting VEGF have further angiogenic potential by releasing HGF.

  7. Presynaptic M1 muscarinic receptor modulates spontaneous release of acetylcholine from rat basal forearm slices

    International Nuclear Information System (INIS)

    Suzuki, T.; Fujimoto, LK.; Oohata, H.; Kawashima, K.

    1988-01-01

    Spontaneous release of (ACh) from rat basal forebrain slices in the presence of cholinesterase inhibitor was directly determined using a specific radioimmunoassay for ACh. The release was calcium dependent. A consistent amount of ACh release was observed throughout the experiment. Atropine (10- 8 to 10- 5 M) and pirenzepine (10- 7 to 10- 5 M) enhanced spontaneous ACh release. These findings indicate the presence of an M 1 muscarenic autoreceptor that modulates spontaneous release of ACh in the rat forebrain

  8. Major Environmental Policy in 2000

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Hong Jin [Ministry Of Environment, Kwachon (Korea)

    2000-04-01

    As a new millennium has started, there are active movements developing a basic paradigm of vision and policy over a nation-wide to prepare changes actively. For the environmental sector, it is possible to live in a pleasant environment if everyone prepare and work together like dealing with Y2K problem. With a goal of being an environmentally advanced country in the early new millennium, it is planned to improve a basic life environment such as water and air and to promote an advanced environmental management policy for showing results of its reform in 2000. Therefore, it examines environmental management circumstances and a direction of environmental policy first and it discusses more about major environmental policy related to petroleum industry. 7 tabs.

  9. Understanding release kinetics of biopolymer drug delivery microcapsules for biomedical applications

    International Nuclear Information System (INIS)

    Desai, Salil; Perkins, Jessica; Harrison, Benjamin S.; Sankar, Jag

    2010-01-01

    Drug delivery and dosage concentrations are considered as major focal points in conventional as well as battlefield emergency medicine. The concept of localizing drug delivery via microcapsules is an evolving field to confine the adverse side effects of high concentration drug doses. This paper focuses on understanding release kinetics through biopolymer microcapsules for time-dependent drug release. Calcium alginate microcapsules were manufactured using a direct-write inkjet technique. Rhodamine 6G was used as the release agent to observe the release kinetics from calcium alginate beads in distilled water. A design of experiments was constructed to compare the effect of the microcapsule diameter and different concentrations of calcium chloride (M) and sodium alginate (%, w/v) solutions on the release kinetics profiles of the microcapsules. This research gives insight to identify favorable sizes of microcapsules and concentrations of sodium alginate and calcium chloride solutions for controlled release behavior of drug delivery microcapsules.

  10. Coordination of environmental policy for transboundary environmental problems?

    Energy Technology Data Exchange (ETDEWEB)

    Hoel, M.

    1996-01-01

    In order to reach a Pareto optimal outcome with transboundary environmental problems, there must be some kind of international agreement. One possibility would be an international agreement focusing directly on emissions in each country. Given such an agreement, an important issue is whether one should supplement the agreement with some kind of policy coordination, or if the choice of environmental policies should be left for each country to decide for itself. The present paper shows that under ``ideal`` conditions, policies need not be coordinated across countries. Such ideal conditions include, among other things, that all markets, including the labour market, are competitive. However, if one has imperfect competition in goods markets, or unemployment, it may be desirable to let an international environmental agreement not only specify emission levels, but also the policy mix between emission taxes and direct regulation. 16 refs.

  11. Pragmatics of policy: the compliance of dutch environmental policy instruments to European union standards.

    Science.gov (United States)

    Kruitwagen, Sonja; Reudink, Melchert; Faber, Albert

    2009-04-01

    Despite a general decrease in Dutch environmental emission trends, it remains difficult to comply with European Union (EU) environmental policy targets. Furthermore, environmental issues have become increasingly complex and entangled with society. Therefore, Dutch environmental policy follows a pragmatic line by adopting a flexible approach for compliance, rather than aiming at further reduction at the source of emission. This may be politically useful in order to adequately reach EU targets, but restoration of environmental conditions may be delayed. However, due to the complexity of today's environmental issues, the restoration of environmental conditions might not be the only standard for a proper policy approach. Consequently this raises the question how the Dutch pragmatic approach to compliance qualifies in a broader policy assessment. In order to answer this question, we adapt a policy assessment framework, developed by Hemerijck and Hazeu (Bestuurskunde 13(2), 2004), based on the dimensions of legitimacy and policy logic. We apply this framework for three environmental policy assessments: flexible instruments in climate policy, fine-tuning of national and local measures to meet air quality standards, and derogation for the Nitrate Directive. We conclude with general assessment notes on the appliance of flexible instruments in environmental policy, showing that a broad and comprehensive perspective can help to understand the arguments to put such policy instruments into place and to identify trade-offs between assessment criteria.

  12. An integrated energy policy for Korea

    International Nuclear Information System (INIS)

    Kim, Tai-Yoo; Kim, Seung-Rae

    1993-01-01

    Economic theory defines a market failure when competitive markets cannot reach an equilibrium maximizing social welfare. One of its most typical examples has proved to be the energy market. Exhaustible energy resources provide the limits to economic growth, at least in the short term. Thus an energy policy for energy importing countries like Korea has been focused on minimizing the negative influences of external energy price shocks to the domestic economy. This study suggests one of the possible directions for an integrated energy policy which seeks to present a flow of policy rules which lead government policy to attain equilibrium, maximizing the national economic benefits by offsetting the market failure

  13. Foreign Language Education Policy on the Horizon

    Science.gov (United States)

    Hult, Francis M.

    2018-01-01

    Language policy has developed into a major area of research that continues to expand and develop. This article examines potential directions for cross-pollination between the fields of language policy and foreign language education. First, publication trends are examined. Database searches were conducted for the journals "Foreign Language…

  14. 48 CFR 237.7502 - Policy.

    Science.gov (United States)

    2010-10-01

    ... DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Acquisition and Management of Industrial Resources 237.7502 Policy. (a) Comply with DoD Directive 4275.5, Acquisition and Management of Industrial...

  15. Contact: Releasing the news

    Science.gov (United States)

    Pinotti, Roberto

    The problem of mass behavior after man's future contacts with other intelligences in the universe is not only a challenge for social scientists and political leaders all over the world, but also a cultural time bomb as well. In fact, since the impact of CETI (Contact with Extraterrestrial Intelligence) on human civilization, with its different cultures, might cause a serious socio-anthropological shock, a common and predetermined worldwide strategy is necessary in releasing the news after the contact, in order to keep possible manifestations of fear, panic and hysteria under control. An analysis of past studies in this field and of parallel historical situations as analogs suggests a definite "authority crisis" in the public as a direct consequence of an unexpected release of the news, involving a devastating "chain reaction" process (from both the psychological and sociological viewpoints) of anomie and maybe the collapse of today's society. The only way to prevent all this is to prepare the world's public opinion concerning contact before releasing the news, and to develop a long-term strategy through the combined efforts of scientists, political leaders, intelligence agencies and the mass media, in order to create the cultural conditions in which a confrontation with ETI won't affect mankind in a traumatic way. Definite roles and tasks in this multi-level model are suggested.

  16. The Vietnamese lending rate, policy-related rate, and monetary policy post-1997 Asian financial crisis

    Directory of Open Access Journals (Sweden)

    Chu V. Nguyen

    2015-12-01

    Full Text Available Asymmetries in the Vietnamese lending central bank’s policy-related rate spread were documented. Empirical results revealed that the spread adjusts to the threshold faster when the central bank’s policy-related rates decrease relative to the lending rates than when the central bank’s policy-related rates move in the opposite direction. Additionally, the empirical findings indicate that Vietnamese commercial banks exhibit competitive rate setting behavior which may be attributable to graft maximization by bank’s management. The results also show bidirectional Granger causality between the Vietnamese lending rate and the central bank’s policy-related rate, indicating that the lending rate and the central bank’s policy-related rate affect each other’s movements. These results suggest that monetary authority can use its countercyclical monetary policy instruments to achieve its macroeconomics objectives. However, the estimation results of the GARCH (2, 3-in-Mean model suggest that they should intervene more frequently and by small policy measures to minimize the conditional variance of the spread to minimize the magnitude of the cycle of the lending rate.

  17. Energy market review releases draft report

    International Nuclear Information System (INIS)

    Anon

    2002-01-01

    The Energy Market Review Releases draft report has made recommendations consistent with the Australian Gas Association (AGA)'s submissions in a number of areas. In particular, it has endorsed: 1. the need for an independent review of the gas access regime, to address the deficiencies with current access regulation identified by the Productivity Commission's Review of the National Access Regime; 2. the need for greater upstream gas market competition; 3. the principle that significant regulatory decisions should be subject to clear merits and judicial review; and 4. the need to avoid restrictions on retail energy prices. The report also endorses the need for a 'technology neutral' approach to greenhouse emissions abatement policy. It states that 'many of the current measures employed to reduce greenhouse gas emissions are poorly targeted', and that they 'target technologies or fuel types rather than greenhouse gas abatement.' Additionally, it explicitly recognises the key conclusions of the AGA's recently-released Research Paper, Reducing Greenhouse Emissions from Water Heating: Natural Gas as a Cost-effective Option. The draft report recommends the development of an economy-wide emissions trading system, to achieve a more cost-effective approach to greenhouse abatement

  18. Endoscopic cubital tunnel release using the Hoffmann technique.

    Science.gov (United States)

    Hoffmann, Reimer; Lubahn, John

    2013-06-01

    Endoscopic cubital tunnel release was originally described in 1989 by Tsai, and his technique has been modified by other surgeons including Mirza and Cobb. In 2006, Hoffmann and Siemionow described an endoscopic technique quite different from Tsai's original description. Instead of working from the "inside out," Hoffmann's technique is performed through an incision similar to that which would be used for an in situ release of the ulnar nerve. The main difference being that the nerve can be explored and decompressed 10 cm proximal and distal to the arcuate ligament as the surgeon looks down on the nerve and the surrounding tissues while viewing the anatomy through a camera attached to a soft tissue endoscope that is inserted in the wound. The arcuate (Osborne's) ligament is released under direct vision much like a standard in situ decompression. Using a blunt dissection instrument, a workspace is created proximally and distally to the cubital tunnel. Next an illuminated speculum is introduced, the nerve is directly visualized between 4 and 5 cm proximal and distal to the cubital tunnel, and potential compressive forearm fasciae or fibrous bands are released. Finally, a 15-cm, 30° soft tissue endoscope is introduced into the incision, and viewing the internal anatomy on a video monitor, the decompression continues using longer scissors. Any potential bleeding is controlled with a long bayonet bipolar cautery. The authors discuss indications, contraindications, and the surgical technique. Postoperative management and associated complications are also discussed. Copyright © 2013 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  19. EU internal energy market policy: new dynamics in the Brussels policy game?

    Energy Technology Data Exchange (ETDEWEB)

    Eikeland, Per Ove

    2008-11-15

    The paper analyses the September 2007 European Commission proposal for a third internal energy policy package. It asks if the proposal reflected fundamental changes in the Brussels policy game from 2003, when the existing legislation had been adopted. A multi-level governance approach has inspired this check of alternative propositions. We find that the proposal was primarily the result of greater will on the part of the Commission to pressure unwilling member-state governments. There is also strong evidence that the Commission pursued a new form of multi-level game, pressing non-state agents directly to change the political game at the national level. Our study finally discusses whether different network approaches would add explanatory power to our study, acknowledging that agents working in larger networks could have greater thrust on the Commission. The main conclusion is that EU policy networks have become less stable and more issue-specific, making policy predictions less certain than before. (author).refs.,tab

  20. Stretch-induced Ca2+ independent ATP release in hippocampal astrocytes.

    Science.gov (United States)

    Xiong, Yingfei; Teng, Sasa; Zheng, Lianghong; Sun, Suhua; Li, Jie; Guo, Ning; Li, Mingli; Wang, Li; Zhu, Feipeng; Wang, Changhe; Rao, Zhiren; Zhou, Zhuan

    2018-02-28

    Similar to neurons, astrocytes actively participate in synaptic transmission via releasing gliotransmitters. The Ca 2+ -dependent release of gliotransmitters includes glutamate and ATP. Following an 'on-cell-like' mechanical stimulus to a single astrocyte, Ca 2+ independent single, large, non-quantal, ATP release occurs. Astrocytic ATP release is inhibited by either selective antagonist treatment or genetic knockdown of P2X7 receptor channels. Our work suggests that ATP can be released from astrocytes via two independent pathways in hippocampal astrocytes; in addition to the known Ca 2+ -dependent vesicular release, larger non-quantal ATP release depends on P2X7 channels following mechanical stretch. Astrocytic ATP release is essential for brain functions such as synaptic long-term potentiation for learning and memory. However, whether and how ATP is released via exocytosis remains hotly debated. All previous studies of non-vesicular ATP release have used indirect assays. By contrast, two recent studies report vesicular ATP release using more direct assays. In the present study, using patch clamped 'ATP-sniffer cells', we re-investigated astrocytic ATP release at single-vesicle resolution in hippocampal astrocytes. Following an 'on-cell-like' mechanical stimulus of a single astrocyte, a Ca 2+ independent single large non-quantal ATP release occurred, in contrast to the Ca 2+ -dependent multiple small quantal ATP release in a chromaffin cell. The mechanical stimulation-induced ATP release from an astrocyte was inhibited by either exposure to a selective antagonist or genetic knockdown of P2X7 receptor channels. Functional P2X7 channels were expressed in astrocytes in hippocampal brain slices. Thus, in addition to small quantal ATP release, larger non-quantal ATP release depends on P2X7 channels in astrocytes. © 2018 The Authors. The Journal of Physiology © 2018 The Physiological Society.

  1. Country policy profile - Cyprus. August 2015

    International Nuclear Information System (INIS)

    2015-08-01

    In 2013, four renewable energy sources (RES) support schemes were implemented in Cyprus: grants and/or subsidies for the use of renewable energy sources and energy saving, regulation on cost of ancillary services and the use of system. Moreover, support is available for investments for the improvement of competitiveness and management of farm waste (RES-Legal Europe, 2014). This report monitors the policy changes after the release of the Cypriotic 2013 Progress Report and is regularly updated

  2. Tunable Molecular Logic Gates Designed for Imaging Released Neurotransmitters.

    Science.gov (United States)

    Klockow, Jessica L; Hettie, Kenneth S; Secor, Kristen E; Barman, Dipti N; Glass, Timothy E

    2015-08-03

    Tunable dual-analyte fluorescent molecular logic gates (ExoSensors) were designed for the purpose of imaging select vesicular primary-amine neurotransmitters that are released from secretory vesicles upon exocytosis. ExoSensors are based on the coumarin-3-aldehyde scaffold and rely on both neurotransmitter binding and the change in environmental pH associated with exocytosis to afford a unique turn-on fluorescence output. A pH-functionality was directly integrated into the fluorophore π-system of the scaffold, thereby allowing for an enhanced fluorescence output upon the release of labeled neurotransmitters. By altering the pH-sensitive unit with various electron-donating and -withdrawing sulfonamide substituents, we identified a correlation between the pKa of the pH-sensitive group and the fluorescence output from the activated fluorophore. In doing so, we achieved a twelvefold fluorescence enhancement upon evaluating the ExoSensors under conditions that mimic exocytosis. ExoSensors are aptly suited to serve as molecular imaging tools that allow for the direct visualization of only the neurotransmitters that are released from secretory vesicles upon exocytosis. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Recidivism after release from a prison nursery program.

    Science.gov (United States)

    Goshin, Lorie S; Byrne, Mary W; Henninger, Alana M

    2014-01-01

    To analyze 3-year recidivism after release from a prison nursery, a secure unit that allows imprisoned women to care for their infants. Descriptive study of 139 women who co-resided with their infants between 2001 and 2007 in a New York State prison nursery. Administrative criminal justice data were analyzed along with prospective study data on demographic, mental health, and prison nursery policy-related factors. Results reflect a sample of young women of color with histories of clinically significant depressive symptoms and substance dependence, who were convicted of nonviolent crimes and had multiple prior arrests. Three years after release 86.3% remained in the community. Only 4% of women returned to prison for new crimes. Survival modeling indicated that women who had previously violated parole had a significantly shorter mean return to prison time than those who were in the nursery for a new crime. Women released from a prison nursery have a low likelihood of recidivism. Innovative interventions are needed to address incarceration's public health effects. Nurses can partner with criminal justice organizations to develop, implement, and evaluate programs to ensure the health needs of criminal justice involved people and their families are met. © 2013 Wiley Periodicals, Inc.

  4. Direct monitoring of dopamine and 5-HT release in substantia nigra and ventral tegmental area in vitro

    DEFF Research Database (Denmark)

    Rice, M E; Richards, C D; Nedergaard, S

    1994-01-01

    Fast-scan cyclic voltammetry with carbon fibre microelectrodes was used to detect endogenous dopamine (DA) and 5-hydroxytryptamine (5-HT) release from three distinct regions of guinea-pig mid-brain in vitro: rostral and caudal substantia nigra (SN) and the ventral tegmental area (VTA). Previous...... these regions with in situ electrodes and demonstrates the utility of fast-scan cyclic voltammetry to investigate the mechanisms and possible non-classical functions of somato-dendritic DA release....

  5. Transport and environment: policy directions for Europe

    International Nuclear Information System (INIS)

    Tinch, R.

    2001-01-01

    Transport externalities are among the most important environmental problems affecting quality of life in Europe. Forecasts suggest that past environmental improvements may now be rolled back by traffic growth, and current traffic trends are not sustainable. The theory of environmental policy proposes pricing external costs at their marginal social costs as one solution. Although full marginal social cost pricing is impracticable, advances in tolling technology and environmental valuation mean that it is now a viable option to approximate such charging. There are signs that the European Commission and other bodies are starting to favour pricing over regulatory instruments. However, often overlooked is the potential for non-convexities in the transport sector or between transport and the rest of the economy. For example it may be that small increases in resources for public transport would not result in welfare gains, whereas large increases would. Non-convexities would mean that market forces under marginal social cost pricing might lead away from the optimal transport system. This is one reason why pricing instruments cannot in themselves be a panacea for transport externalities or bring about a sustainable transport system. (Author)

  6. 48 CFR 9904.407 - Use of standard costs for direct material and direct labor.

    Science.gov (United States)

    2010-10-01

    ... ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.407 Use of standard costs for direct...

  7. Flood Risk Management Policy in Scotland: Research Questions Past, Present and Future

    Science.gov (United States)

    Wilkinson, Mark; Hastings, Emily; MacDonald, Jannette

    2016-04-01

    Scotland's Centre of Expertise for Waters (CREW) delivers accessible research and expert opinion to support the Scottish Government and its delivery partners in the development and implementation of water policy. It was established in 2011 by the Scottish Government (Rural and Environmental Science and Analytical Services) in recognition of a gap in the provision of short term advice and research to policy (development and implementation). Key policy areas include the Water Framework Directive, Floods Directive, Drinking Water Directive, Habitats Directive and Scotland's Hydro Nation Strategy. CREW is unique in its demand-driven and free service for policy makers and practitioners, managing the engagement between scientists, policy makers and practitioners to work effectively across this interface. The users of CREW are the Scottish Government, Scottish Environment Protection Agency, Scottish Natural Heritage and Scottish Water. CREW has funded around 100 projects relating to water policy since its inception in 2011. Of these, a significant number relate to flood risk management policy. Based on a review of work to date, this poster will give an overview of these projects and a forward look at the challenges that remain. From learning from community led flood risk management to surface water flood forecasting for urban communities, links will be made between sustainable and traditional flood risk management while considering the perceptions of stakeholders to flood risk management. How can we deliver fully integrated flood risk management options? How policy makers, scientists and land managers can better work together will also be explored.

  8. How Smog Awareness Influences Public Acceptance of Congestion Charge Policies

    Directory of Open Access Journals (Sweden)

    Lingyi Zhou

    2017-09-01

    Full Text Available Although various studies have investigated public acceptance of congestion charge policies, most of them have focused on behavioral and policy-related factors, and did not consider the moderating influence that individual concern about smog and perceived smog risk may have on public acceptance. This paper takes the congestion charge policy in China, targeted at smog and traffic control, and checks how smog awareness—including smog concerns and perceived smog risks, besides behavioral and policy-related factors—might influence public acceptance of the policy. In this paper, we found both a direct and moderating causal relationship between smog awareness and public acceptance. Based on a sample of 574 valid questionnaires in Beijing and Shanghai in 2016, an ordered logistic regression modeling approach was used to delineate the causality between smog awareness and public acceptance. We found that both smog concerns, such as perceived smog risk, and willingness to pay (WTP were both directly and indirectly positively correlated with public acceptance. These findings imply that policymakers should increase policy fairness with environmental-oriented policy design and should express potential policy effectiveness of the smog controlling policy to citizens to increase their acceptance level.

  9. Impairment of Release Site Clearance within the Active Zone by Reduced SCAMP5 Expression Causes Short-Term Depression of Synaptic Release

    Directory of Open Access Journals (Sweden)

    Daehun Park

    2018-03-01

    Full Text Available Summary: Despite being a highly enriched synaptic vesicle (SV protein and a candidate gene for autism, the physiological function of SCAMP5 remains mostly enigmatic. Here, using optical imaging and electrophysiological experiments, we demonstrate that SCAMP5 plays a critical role in release site clearance at the active zone. Truncation analysis revealed that the 2/3 loop domain of SCAMP5 directly interacts with adaptor protein 2, and this interaction is critical for its role in release site clearance. Knockdown (KD of SCAMP5 exhibited pronounced synaptic depression accompanied by a slower recovery of the SV pool. Moreover, it induced a strong frequency-dependent short-term depression of synaptic release, even under the condition of sufficient release-ready SVs. Super-resolution microscopy further proved the defects in SV protein clearance induced by KD. Thus, reduced expression of SCAMP5 may impair the efficiency of SV clearance at the active zone, and this might relate to the synaptic dysfunction observed in autism. : Park et al. show that SCAMP5 plays an important role in release site clearance during intense neuronal activity. Loss of SCAMP5 results in a traffic jam at release sites, causing aberrant short-term synaptic depression that might be associated with the synaptic dysfunction observed in autism. Keywords: secretory carrier membrane protein, SCAMP5, autism spectrum disorder, adaptor protein 2, release site clearance, presynaptic active zone, short-term depression, endocytosis, super-resolution microscopy

  10. Controlled release of biofunctional substances by radiation-induced polymerization

    International Nuclear Information System (INIS)

    Yoshida, M.; Kumakura, M.; Kaetsu, I.

    1978-01-01

    The controlled release of potassium chloride from flat circular matrices made by radiation-induced polymerization of a glass-forming monomer at low temperatures has been studied. The water-particle phase content formed in a poly(diethylene glycol dimethacrylate) matrix was controlled by the addition of polyethylene glycol 600. The dispersed water-particle phase content in the matrix was estimated directly and by scanning electron microscopic observations. The release of potassium chloride from the matrix increased linearly with the square root of time. The water content of the matrix had an important effect on the release rate which increases roughly in proportion to water content. This effect can be attributed to the apparent increase of the rate of drug diffusion. (author)

  11. Policy stability and democratic change

    Energy Technology Data Exchange (ETDEWEB)

    Lancaster, T.D.

    1989-01-01

    This book examines the effects of peaceful regime change on public policy making. Spain's National Energy Plan (PEN) in particular illustrates a situation in which a critical policy issue permits direct comparison of decision making across regime change, that being from the Franco dictatorship to the present liberal democracy. Energy policy in Spain is revealing not only because the Spanish state plays a central role in this fundamental economic area but also because the first PEN was caught up in the politics of the transition; it was written in 1977 but not approved by the Cortes until 1979, and its revision was published in early 1982.

  12. Marijuana: A Study of State Policies & Penalties.

    Science.gov (United States)

    Peat, Marwick, Mitchell and Co., Columbia, MD.

    This study is a comprehensive analysis of issues concerning marijuana that are of importance to state policy makers. It reviews the medical, legal, and historical dimensions of marijuana use and examines the range of policy approaches toward marijuana possession and use which state officials have considered. Attention is directed to the experience…

  13. Economic Models as Devices of Policy Change

    DEFF Research Database (Denmark)

    Henriksen, Lasse Folke

    2013-01-01

    Can the emergence of a new policy model be a catalyst for a paradigm shift in the overall interpretative framework of how economic policy is conducted within a society? This paper claims that models are understudied as devices used by actors to induce policy change. This paper explores the role...... of models in Danish economic policy, where, from the 1970s onwards, executive public servants in this area have exclusively been specialists in model design. To understand changes in economic policy, this paper starts with a discussion of whether the notion of paradigm shift is adequate. It then examines...... the extent to which the performativity approach can help identify macroscopic changes in policy from seemingly microscopic changes in policy models. The concept of performativity is explored as a means of thinking about the constitution of agency directed at policy change. The paper brings this concept...

  14. Library Operations Policies and Procedures, Volume 2. Central Archive for Reusable Defense Software (CARDS)

    Science.gov (United States)

    1994-02-28

    use and customize those policies and procedures applicable to the implementor’s situation. It is not the intent of this manual to restrict the library...improvements. Pare 10 ka•- V •DkI U Release Manager The Release Manager provides franchisees with media copies of existing libraries, as needed. Security...implementors, and potential library franchisees . Security Team The Security Team assists the Security Officer with security analysis. Team members are

  15. Party politics and Greek security policy from 1974 to 1984: change and continuity

    OpenAIRE

    Haines, John L.

    1984-01-01

    Approved for public release; distribution is unlimited This thesis explores the effects of political change on Greek security policy during the period 1974 to 1984. This period encompasses significant change in Greece's foreign relations including those with the United States. The central question is: Are the elements of Greek security policy based on long-term basic interests which find consistent expression, or are they a function of domestic political factors, more ideologicall...

  16. Modelling Common Agricultural Policy-Water Framework Directive interactions and cost-effectiveness of measures to reduce nitrogen pollution.

    Science.gov (United States)

    Mouratiadou, Ioanna; Russell, Graham; Topp, Cairistiona; Louhichi, Kamel; Moran, Dominic

    2010-01-01

    Selecting cost-effective measures to regulate agricultural water pollution to conform to the Water Framework Directive presents multiple challenges. A bio-economic modelling approach is presented that has been used to explore the water quality and economic effects of the 2003 Common Agricultural Policy Reform and to assess the cost-effectiveness of input quotas and emission standards against nitrate leaching, in a representative case study catchment in Scotland. The approach combines a biophysical model (NDICEA) with a mathematical programming model (FSSIM-MP). The results indicate only small changes due to the Reform, with the main changes in farmers' decision making and the associated economic and water quality indicators depending on crop price changes, and suggest the use of target fertilisation in relation to crop and soil requirements, as opposed to measures targeting farm total or average nitrogen use.

  17. Country policy profile - Cyprus. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    In 2013, four renewable energy sources (RES) support schemes were implemented in Cyprus: grants and/or subsidies for the use of renewable energy sources and energy saving, regulation on cost of ancillary services and the use of system. Moreover, support is available for investments for the improvement of competitiveness and management of farm waste (RES-Legal Europe, 2014). This report monitors the policy changes after the release of the Cypriot 2013 Progress Report and is has been updated until December 2015

  18. Nuclear energy national plan. The directions for nuclear energy policy in Japan

    International Nuclear Information System (INIS)

    2006-11-01

    Nuclear energy is a key attaining an integrated solution for energy security and global warming issues. Under the Framework for Nuclear Energy Policy Japan aims to (1) maintain the 30 to 40% or more share of nuclear energy on electricity generation up to 2030 and afterwards, (2) promote the nuclear fuel cycle and (3) commercialize the fast-breeder reactors. As for policies to realize the basic targets, the 'Nuclear Energy National Plan' was compiled in August 2006 as follows: (1) Investment to construct new nuclear power plants and replace existing reactors in an era of electric power liberalization, 2) Appropriate use of existing nuclear power plants with assuring safety as a key prerequisite, (3) Steady advancement of the nuclear fuel cycle and strategic reinforcement of nuclear fuel cycle industries, (4) Strategy to secure uranium supplied, (5) Early commercialization of the fast breeder reactor cycle, (6) Achieving and developing advanced, technologies, industries and personnel, (7) Assisting the Japanese nuclear industry in promoting the international development, (8) Involved in and/or creating international frameworks to uphold both nonproliferation and expansion of nuclear power generation, (9) Fostering trust between the sates and communities where plants are located by making public hearings and public relations highly detailed and (10) Steady promotion of measures for disposal of radioactive wastes. Implementation policies were presented in details in this book with relevant data and documents. (T. Tanaka)

  19. 3 CFR - Continuation of the National Emergency With Respect to the Actions and Policies of Certain...

    Science.gov (United States)

    2010-01-01

    ... processes or institutions; committed human rights abuses related to political repression, including..., including the release of internationally recognized political prisoners, the actions and policies of certain...

  20. Grenada School Nutrition Study: Evidence to Inform Policy | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Grenada School Nutrition Study: Evidence to Inform Policy ... LMICs can direct their efforts to changing the environments and habits that promote ... Report Card that will be suited for advocacy work, and could be used to influence policy.

  1. Lyophilized sustained release mucoadhesive chitosan sponges for buccal buspirone hydrochloride delivery: formulation and in vitro evaluation.

    Science.gov (United States)

    Kassem, Mohamed A A; ElMeshad, Aliaa N; Fares, Ahmed R

    2015-06-01

    This work aims to prepare sustained release buccal mucoadhesive lyophilized chitosan sponges of buspirone hydrochloride (BH) to improve its systemic bioavailability. Chitosan sponges were prepared using simple casting/freeze-drying technique according to 3(2) factorial design where chitosan grade was set at three levels (low, medium, and high molecular weight), and concentration of chitosan solution at three levels (0.5, 1, and 2%). Mucoadhesion force, ex vivo mucoadhesion time, percent BH released after 8 h (Q8h), and time for release of 50% BH (T50%) were chosen as dependent variables. Additional BH cup and core buccal chitosan sponge were prepared to achieve uni-directional BH release toward the buccal mucosa. Sponges were evaluated in terms of drug content, surface pH, scanning electron microscopy, swelling index, mucoadhesion strength, ex vivo mucoadhesion time, and in vitro drug release. Cup and core sponge (HCH 0.5E) were able to adhere to the buccal mucosa for 8 h. It showed Q8h of 68.89% and exhibited a uni-directional drug release profile following Higuchi diffusion model.

  2. Release procedures and disposal of radioactive residual substances at the Medical University Hanover (MHH)

    International Nuclear Information System (INIS)

    Scheller, F.; Behrendt, R.; Harke, H.

    2005-01-01

    The disposal of all radioactive residual packages of the MHH is regulated by the German radiation protection ordinance from 26 th July 2001; shown in appendix III, table 1, column 5: unrestricted release of solid materials and liquids. All radioactive waste packages are collected and handled by the central MHH department for radiation protection. They are sorted for type, nuclide and specific radioactivity. A few packages can directly be released as conventional waste after performing incoming measurements showing very low activity concentrations. Longer living radionuclides with specific activities above the release limits have to be delivered to the national waste disposal. For direct measurements of gamma-emitting radionuclides we use two in-situ-measuring units (ISOCS, Canberra) and a special release unit with 9 plastic scintillators in a fixed geometry (FR-9 PVT, MED Medizintechnik). Fluid beta-emitting radionuclides are measured by taking a fraction and using liquid scintillation counting (LSC). Solid beta-emitting radionuclides activity are calculated. (orig.)

  3. Direct Energy Marketing Ltd. 1998 annual report

    International Nuclear Information System (INIS)

    1999-01-01

    A corporate profile of Direct Energy Marketing Ltd. was presented for the benefit of shareholders. Direct Energy is responsible for marketing and distributing natural gas to residential, commercial and industrial customers. The company owns physical natural gas reserves that serve as a supply hedge to its growing customer base. The highlights for the natural gas distribution income fund (OPTUS) for 1998 were described. OPTUS acquired WestCastle Energy, adding 38 mmcf/d of natural gas supply. It also amalgamated Channel Lake Petroleum and WestCastle Energy into Direct Energy and created the production division, Direct Energy Resources. It also formed Energy America with Sempra Energy, adding over 160,000 retail customers in Michigan and Ohio. Direct Energy's consolidated financial statements were presented for the benefit of shareholders. These included statements of earnings and deficit, balance sheets, and statements of changes in financial position. Notes to the consolidated financial statements included highlights of significant accounting policies, changes in accounting policies, acquisitions, discontinued operations, and capital assets. tabs., figs

  4. Containment response and radiological release for a TMLB' accident sequence in a large dry containment

    International Nuclear Information System (INIS)

    Gasser, R.D.; Bieniarz, P.P.; Tills, J.L.

    1987-01-01

    An analysis has been performed for the Bellefonte Pressurized Water Reactor (PWR) Unit 1 to determine the containment loading and the radiological releases into the environment from a station blackout accident. A number of issues have been addressed in this analysis, which include the effects of direct heating on containment loading and the effects of fission product heating and natural convection on releases from the primary system. The results indicate that direct heating, which involves more than about 50% of the core, may fail the Bellefonte containment, but natural convection in the Reactor Coolant System (RCS) may lead to overheating and failure of the primary system piping before core slump, thus, eliminating or mitigating direct heating. Releases from the primary system are significantly increased before vessel breach, due to natural circulation, and after vessel breach, due to reevolution of retained fission products by fission product heating of RCS structures. (orig.)

  5. Road pricing policy implementation

    NARCIS (Netherlands)

    Vonk Noordegraaf, D.M.

    2016-01-01

    Urban areas suffer from the negative externalities of road transport like congested road networks, air pollution and road traffic accidents. A measure to reduce these negative externalities is road pricing, meaning policies that impose direct charges on road use (Jones and Hervik, 1992). Since the

  6. A review of EIAs on trade policy in China: Exploring the way for economic policy EIAs

    Energy Technology Data Exchange (ETDEWEB)

    Mao, Xianqiang, E-mail: maoxq@bnu.edu.cn [Center for Global Environmental Policy, School of Environment, Beijing Normal University, Beijing 100875 (China); Song, Peng, E-mail: songpeng_ee@163.com [Center for Global Environmental Policy, School of Environment, Beijing Normal University, Beijing 100875 (China); Kørnøv, Lone, E-mail: lonek@plan.aau.dk [The Danish Centre for Environmental Assessment, Department of Planning, Aalborg University, Skibbrogade 5, B1-04, 9000 Aalborg (Denmark); Corsetti, Gabriel, E-mail: gabriel.corsetti@gmail.com [Center for Global Environmental Policy, School of Environment, Beijing Normal University, Beijing 100875 (China)

    2015-01-15

    During the discussion on the “Environmental Protection Law Amendment (draft)” in 2011, it was decided to drop the proposed clauses related to environmental impact assessments (EIAs) on policy, which means that there remained no provisions for policy EIAs, and China's strategic environmental assessment system stayed limited to the planning level. However, considering that economic policy making is causing significant direct and indirect environmental problems and that almost every aspect of governmental policy has an economic aspect, EIAs on economic policies are of the utmost urgency. The purpose of this study is to review the EIA work that has been carried out on trade policy in China through four case studies, and illustrate how trade policy EIAs can be helpful in achieving better environmental outcomes in the area of trade. Through the trade policy EIA case studies we try to argue for the feasibility of conducting EIAs on economic policies in China. We also discuss the implications of the case studies from the point of view of how to proceed with EIAs on economic policy and how to promote their practice. - Highlights: • SEA system is incomplete and stays limited to the plan EIA level in China. • EIA on economic policy is of utmost importance for all the developing countries. • Four case studies of trade policy EIA in China are reviewed for policy implications. • Departmental competition for political power impedes economic policy EIAs in China. • Legislative regulation on policy EIA is the first thing needed to overcome barrier.

  7. A review of EIAs on trade policy in China: Exploring the way for economic policy EIAs

    International Nuclear Information System (INIS)

    Mao, Xianqiang; Song, Peng; Kørnøv, Lone; Corsetti, Gabriel

    2015-01-01

    During the discussion on the “Environmental Protection Law Amendment (draft)” in 2011, it was decided to drop the proposed clauses related to environmental impact assessments (EIAs) on policy, which means that there remained no provisions for policy EIAs, and China's strategic environmental assessment system stayed limited to the planning level. However, considering that economic policy making is causing significant direct and indirect environmental problems and that almost every aspect of governmental policy has an economic aspect, EIAs on economic policies are of the utmost urgency. The purpose of this study is to review the EIA work that has been carried out on trade policy in China through four case studies, and illustrate how trade policy EIAs can be helpful in achieving better environmental outcomes in the area of trade. Through the trade policy EIA case studies we try to argue for the feasibility of conducting EIAs on economic policies in China. We also discuss the implications of the case studies from the point of view of how to proceed with EIAs on economic policy and how to promote their practice. - Highlights: • SEA system is incomplete and stays limited to the plan EIA level in China. • EIA on economic policy is of utmost importance for all the developing countries. • Four case studies of trade policy EIA in China are reviewed for policy implications. • Departmental competition for political power impedes economic policy EIAs in China. • Legislative regulation on policy EIA is the first thing needed to overcome barrier

  8. Public Policies Analysis and the Prince System

    Directory of Open Access Journals (Sweden)

    Behxhet Brajshori

    2017-07-01

    Full Text Available Public Policies present governmental sectorial policies and according to several scholars those are defined based on "what does the Government do". In fact, those are mandatory state's principles for the Government that aims the implementation of the strategy, objectives and Government's goals in the function of its promises' fulfilment towards the electors and all of the country's citizens. Public Policies Analysis has to do with the monitoring of government's agenda which directly can influence on a specific community. The idea of public policies analysis in linked with the need that the Government through statistical data has to prove what is being worked. Public Policies Analysis evolves in terms of design, implementation and public policies' effects. One of the methods for predicting the probability that a specifi c public policy will be implemented or not, is the Prince System. The Prince System, actually, presents a technique for assessing the relative support or opposition to a particular policy from individuals, groups or organizations.

  9. Integrated performance assessment model for waste policy package behavior and radionuclide release

    International Nuclear Information System (INIS)

    Kossik, R.; Miller, I.; Cunnane, M.

    1992-01-01

    Golder Associates Inc. (GAI) has developed a probabilistic total system performance assessment and strategy evaluation model (RIP) which can be applied in an iterative manner to evaluate repository site suitability and guide site characterization. This paper describes one component of the RIP software, the waste package behavior and radionuclide release model. The waste package component model considers waste package failure by various modes, matrix alteration/dissolution, and radionuclide mass transfer. Model parameters can be described as functions of local environmental conditions. The waste package component model is coupled to component models for far-field radionuclide transport and disruptive events. The model has recently been applied to the proposed repository at Yucca Mountain

  10. Measuring the Effect of Gender-Based Policies on Economic Growth

    OpenAIRE

    Pierre-Richard Agénor; Otaviano Canuto

    2012-01-01

    To this day, policy makers, policy advisers, and economists in development institutions do not have any practical tools to help them to assess the impacts of policies aimed at promoting gender equality and quantify the effect of these policies on growth. Yet, there has been limited effort in that direction. This note lays out such a tool, a framework for quantifying the growth effects of g...

  11. Quantification of tephritid fruit fly dispersal. Guidelines for a sterile release programme

    International Nuclear Information System (INIS)

    Baker, P.S.; Chan, A.S.T.

    1991-01-01

    The dispersal of sterile Anastrepha ludens and Ceratitis capitata was studied in a mango and coffee plantation in Chiapas, S. Mexico. Flies were released at the centre of a rectangular array of McPhail and Jackson traps. There were small though significant downwind movements in very light winds (below 1 m/s). Fly distributions were significantly correlated in the x-y plane on several days and these orientations were also related to wind direction. Released flies disappeared quickly, more than 90 % were caught within 5 days of release. Methodology for the presentation and analysis of data is discussed in relation to the needs of a practical sterile release programme. Recommendations are made for routine studies of fly dispersal

  12. Benchmarking and Sustainable Transport Policy

    DEFF Research Database (Denmark)

    Gudmundsson, Henrik; Wyatt, Andrew; Gordon, Lucy

    2004-01-01

    Order to learn from the best. In 2000 the European Commission initiated research to explore benchmarking as a tool to promote policies for ‘sustainable transport’. This paper reports findings and recommendations on how to address this challenge. The findings suggest that benchmarking is a valuable...... tool that may indeed help to move forward the transport policy agenda. However, there are major conditions and limitations. First of all it is not always so straightforward to delimit, measure and compare transport services in order to establish a clear benchmark. Secondly ‘sustainable transport......’ evokes a broad range of concerns that are hard to address fully at the level of specific practices. Thirdly policies are not directly comparable across space and context. For these reasons attempting to benchmark ‘sustainable transport policies’ against one another would be a highly complex task, which...

  13. RELEASE AND MUCOADHESION PROPERTIES OF DICLOFENAC MATRIX TABLETS FROM NATURAL AND SYNTHETIC POLYMER BLENDS.

    Science.gov (United States)

    Odeniyi, Michael A; Khan, Nasir H; Peh, Kok K

    2015-01-01

    The delayed release and mucoadhesive properties of Cedrela gum and hydroxypropylmethylcellulose blend in diclofenac sodium tablet formulations were evaluated. Tablets were prepared by direct compression and the crushing strength and detachment force were found to increase from 74.49 ± 1.22 to 147.25 ± 2.57 N and 0.302 ± 0.36 to 1.141 ± 0.05 N from low to high level of polymers, respectively. The release kinetics followed Korsmeyer-Peppas release and the n varied between 0.834 and 1.273, indicating that the release mechanism shifts from Fickian to super case I (anomalous release). The drug release profile fits a pulsatile-release pattern characterized by a lag time followed by a more or less rapid and complete drug release. The Cedrela gum-hydroxypropylmethylcelluse blend tablets delayed diclofenac release for 2 h and sustained the release for 12 h. The polymer blend delayed drug release in the 0.1 M HCl simulating gastric environment and subsequent release pH 6.8 phosphate buffer.

  14. Transition to low carbon energy policies in China-from the Five-Year Plan perspective

    International Nuclear Information System (INIS)

    Yuan Xueliang; Zuo Jian

    2011-01-01

    Energy policy plays a critical role not only in the energy development, but also in the social and environmental aspects of a nation. Five-Year Plan for National Economic and Social Development is one of the most important government plans, which documents the national strategy during that period. This study presents a critical review of 12 Five-Year Plans that have been released by the Chinese central government in last 58 years. In particular, the recently released Twelfth Five-Year Plan is reviewed. The results clearly show a pattern of increasingly level of attention of Chinese government to energy efficiency improvement, air pollutant emission reduction, new and renewable energy development, carbon dioxide emission and climate change. - Highlights: → Critical review of the energy related contents in the 12 Five-Year Plans. → Energy policy of China is focusing on energy efficiency, new and renewable energy. → China is improving the capability of dealing with CO 2 emission and climate change. → China is on transition to low carbon energy policies for a sustainable development.

  15. Technological policy and wage inequality

    OpenAIRE

    Cozzi, Guido; Impullitti, Giammario

    2006-01-01

    In this paper we argue that government procurement policy played a role in stimulating the wave of innovation that hit the US economy in the 1980's, as well as the simultaneous increase in inequality and in education attainment. Since the early 1980's U.S. policy makers began targeting commercial innovations more directly and explicitly. We focus on the shift in the composition of public demand towards high-tech goods which, by increasing the market-size of innovative �rms, fun...

  16. Self-Replenishing Vascularized Fouling-Release Surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Howell, C; Vu, TL; Lin, JJ; Kolle, S; Juthani, N; Watson, E; Weaver, JC; Alvarenga, J; Aizenberg, J

    2014-08-13

    Inspired by the long-term effectiveness of living antifouling materials, we have developed a method for the self-replenishment of synthetic biofouling-release surfaces. These surfaces are created by either molding or directly embedding 3D vascular systems into polydimethylsiloxane (PDMS) and filling them with a silicone oil to generate a nontoxic oil-infused material. When replenished with silicone oil from an outside source, these materials are capable of self-lubrication and continuous renewal of the interfacial fouling-release layer. Under accelerated lubricant loss conditions, fully infused vascularized samples retained significantly more lubricant than equivalent nonvascularized controls. Tests of lubricant-infused PDMS in static cultures of the infectious bacteria Staphylococcus aureus and Escherichia coli as well as the green microalgae Botryococcus braunii, Chlamydomonas reinhardtii, Dunaliella sauna, and Nannochloropsis oculata showed a significant reduction in biofilm adhesion compared to PDMS and glass controls containing no lubricant. Further experiments on vascularized versus nonvascularized samples that had been subjected to accelerated lubricant evaporation conditions for up to 48 h showed significantly less biofilm adherence on the vascularized surfaces. These results demonstrate the ability of an embedded lubricant-filled vascular network to improve the longevity of fouling-release surfaces.

  17. Desirable Strategic Petroleum Reserves policies in response to supply uncertainty: A stochastic analysis

    International Nuclear Information System (INIS)

    Bai, Yang; Zhou, Peng; Tian, Lixin; Meng, Fanyi

    2016-01-01

    Highlights: • A stochastic model is proposed to study Strategic Petroleum Reserves (SPR) policy. • The model aims to find desirable SPR size, acquisition, drawdown and refilling policy. • The impact of SPR policy and supply disruption on oil price has been examined. - Abstract: The paper proposes a survey on three issues related to Strategic Petroleum Reserves (SPR) policy. Firstly, what are the optimal SPR acquisition, drawdown and refilling policy in response to various market risks? Secondly, how SPR policy or actions will affect the market factors, i.e. oil demand or price. Thirdly, in what extend a disruption may induce price shock. For the purpose, the study proposed a Markov Decision Process model (SPR-MDP). In the model, oil supply, disruption size and duration are considered to be highly stochastic. Oil price is determined by market fundamentals exclusively. According to the empirical study, we come to some interesting conclusions. Firstly, oil price and disruption risk show different ways in influencing the desirable SPR size. It is found that the SPR size increases with the decrease of oil price while increase of disruption risk. Secondly, SPR acquisition may increase oil price slightly by influencing the basic fundamentals. In given case, we find acquisition of 7 million barrels per month increase the price by 2.6%. But the influence weakens with decrease of acquisition size. Thirdly, disruption duration shows significant impact on SPR drawdown policy. In a two-month disruption case, it is found that 51% of SPR should be released in the first month. Another 40% is released in the following month. The other 9% SPR is left for forthcoming disruptions. Meanwhile, SPR drawdown shows high efficient in damping oil price in the disruption. In given case, after drawdown of SPR, the oil prices only increases by 0.7% in the second month though continue disruption.

  18. Modelling tools to support the harmonization of Water Framework Directive and Common Agricultural Policy

    Science.gov (United States)

    Tediosi, A.; Bulgheroni, C.; Sali, G.; Facchi, A.; Gandolfi, C.

    2009-04-01

    After a few years from the delivery of the EU Water Framework Directive (WFD) the need to link agriculture and WFD has emerged as one of the highest priorities; therefore, it is important to discuss on how the EU Common Agricultural Policy (CAP) can contribute to the achievements of the WFD objectives. The recent CAP reform - known as Mid Term Review (MTR) or Fischler Reform - has increased the opportunities, offering to farmers increased support to address some environmental issues. The central novelty coming from the MTR is the introduction of a farm single payment which aims to the Decoupling of EU Agricultural Support from production. Other MTR important topics deal with the Modulation of the payments, the Cross-Compliance and the strengthening of the Rural Development policy. All these new elements will affect the farmers' behaviour, steering their productive choices for the future, which, in turn, will have consequences on the water demand for irrigation. Indeed, from the water quantity viewpoint, agriculture is a large consumer and improving water use efficiency is one of the main issues at stake, following the increasing impacts of water scarcity and droughts across Europe in a context of climate change. According to a recent survey of the European Commission the saving potential in the agricultural sector is 43% of present abstraction and 95% of it is concentrated in southern europe. Many models have been developed to forecast the farmers' behaviour as a consequence of agricultural policies, both at sector and regional level; all of them are founded on Mathematical Programming techniques and many of them use the Positive approach, which better fits the territorial dimension. A large body of literature also exists focusing on the assessment of irrigation water requirements. The examples of conjunctive modelling of the two aspects are however much more limited. The work presented has got some innovative aspects: not only does it couple an economical model

  19. A controlled release of ibuprofen by systematically tailoring the morphology of mesoporous silica materials

    International Nuclear Information System (INIS)

    Qu Fengyu; Zhu Guangshan; Lin Huiming; Zhang Weiwei; Sun Jinyu; Li Shougui; Qiu Shilun

    2006-01-01

    A series of mesoporous silica materials with similar pore sizes, different morphologies and variable pore geometries were prepared systematically. In order to control drug release, ibuprofen was employed as a model drug and the influence of morphology and pore geometry of mesoporous silica on drug release profiles was extensively studied. The mesoporous silica and drug-loaded samples were characterized by X-ray diffraction, Fourier transform IR spectroscopy, N 2 adsorption and desorption, scanning electron microscopy, and transmission electron microscopy. It was found that the drug-loading amount was directly correlated to the Brunauer-Emmett-Teller surface area, pore geometry, and pore volume; while the drug release profiles could be controlled by tailoring the morphologies of mesoporous silica carriers. - Graphical abstract: The release of ibuprofen is controlled by tailoring the morphologies of mesoporous silica. The mesoporous silica and drug-loaded samples are characterized by powder X-ray diffraction, Fourier transform IR spectroscopy, N 2 adsorption and desorption, scanning electron microscopy, and transmission electron microscopy. The drug-loading amount is directly correlated to the Brunauer-Emmett-Teller surface area, pore geometry, and pore volume; while the drug release profiles can be controlled by tailoring the morphologies of mesoporous silica carriers

  20. Recent trends in policies, socioeconomy and future directions of the biodiesel industry

    Energy Technology Data Exchange (ETDEWEB)

    Ng, J.H.; Ng, Hoon Kiat [University of Nottingham Malaysia Campus, Department of Mechanical, Materials and Manufacturing Engineering, Semenyih, Selangor (Malaysia); Gan, S. [University of Nottingham Malaysia Campus, Department of Chemical and Environmental Engineering, Semenyih, Selangor (Malaysia)

    2010-06-15

    The growing uncertainty of available petroleum reserves and the associated environmental impacts from the usage of fossil fuels has led to a worldwide search for renewable energy sources. Biodiesel is currently placed at the forefront as the most viable alternative fuel for compression ignition engines as it can be produced from renewable sources through simple cost-effective transesterification, while being compatible with existing infrastructures. Despite these, biodiesel is still not economically feasible for large-scale adoption at present day, mainly due to the high cost of conventional feedstocks. Governmental policies, fiscal incentives and emissions laws have all shown to encourage the uptake of biodiesel in the early stages of market development. The rapid growth enjoyed by the biodiesel industry thereafter has raised concerns of various ethical issues, which must be addressed if the industry is to maintain its positive growth. The strategies required for a stable and sustained biodiesel industry will predominantly be based on the principles of a free market with minimal artificial interventions from policy makers, and the appropriate technological advances in production techniques and feedstocks options to stay competitive economically. This paper reviews the recent trends in global policies and legislative measures governing the economy of the biodiesel industry, and how these will impact the future outlook of the industry as a whole. Historical backgrounds and pertinent issues on socioeconomical and ethical aspects of the industry are also addressed here. (orig.)

  1. 29 CFR 786.1 - Enforcement policy concerning performance of nonexempt work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Enforcement policy concerning performance of nonexempt work... OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS MISCELLANEOUS EXEMPTIONS Carriers by Air § 786.1 Enforcement policy concerning performance of nonexempt work...

  2. 29 CFR 786.100 - Enforcement policy concerning performance of nonexempt work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Enforcement policy concerning performance of nonexempt work..., DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS MISCELLANEOUS EXEMPTIONS Switchboard Operator Exemption § 786.100 Enforcement policy concerning performance of...

  3. 29 CFR 786.200 - Enforcement policy concerning performance of nonexempt work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Enforcement policy concerning performance of nonexempt work..., DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS MISCELLANEOUS EXEMPTIONS Taxicab Operators § 786.200 Enforcement policy concerning performance of nonexempt work...

  4. Health-related direct-to-consumer genetic testing: a review of companies' policies with regard to genetic testing in minors.

    Science.gov (United States)

    Borry, Pascal; Howard, Heidi C; Sénécal, Karine; Avard, Denise

    2010-03-01

    More and more companies are advertising and selling genetic tests directly to consumers. Considering the ethical, legal, and psychological concerns surrounding genetic testing in minors, a study of companies' websites was performed in order to describe and analyze their policies with respect to this issue. Of the 29 companies analyzed, 13 did not provide any information about this matter, eight companies allowed genetic testing upon parental request, four companies stated that their website is not directed to children under 18 years, and four companies suggested that in order to be tested, applicants should have reached the age of legal majority. If private companies offer genetic tests which are also offered in a clinical setting, can they be expected to adhere to the existing clinical guidelines with regard to these tests? If so, a certain ambiguity exists. Many companies are emphasizing in their disclaimers that their services are not medical services and should not be used as a basis for making medical decisions. Nonetheless, it remains debatable whether genetic testing in minors would be appropriate in this context. In line with the Advisory Committee on Genetic Testing, the Human Genetics Commission addressed the problem of non-consensual testing and recommended not to supply genetic testing services directly to those under the age of 16 or to those not able to make a competent decision regarding testing.

  5. Accidental Continuous Releases from Coal Processing in Semi-Confined Environment

    Directory of Open Access Journals (Sweden)

    Bruno Fabiano

    2013-09-01

    Full Text Available Notwithstanding the enforcement of ATEX EU Directives (94/9/EC of 23 March 1994 and safety management system application, explosions in the coal sector still claim lives and cause huge economic losses. Even a consolidated activity like coke dry distillation allows the opportunity of preventing explosion risk connected to fugitive emissions of coke oven gas. Considering accidental releases under semi-confined conditions, a simplified mathematical approach to the maximum allowed gaseous build-up is developed on the basis of the intrinsic hazards of the released compound. The results will help identifying and assessing low rate release consequences therefore to set-up appropriate prevention and control measures. The developed methodology was tested at the real-scale and validated by numerical computational fluid dynamics (CFD simulations showing the effectiveness of the methodology to evaluate and mitigate the risk connected to confined hazardous releases.

  6. THE DIRECTIONS OF IMPROVEMENT OF A COMPETITION POLICY ON THE BASIS OF DEVELOPMENT OF CONTRACT FORMS OF JOINT ACTIVITY OF SMALL AND LARGE BUSINESS

    Directory of Open Access Journals (Sweden)

    N. A. Serebriakova

    2014-01-01

    Full Text Available Summary: The analysis of the foreign economic theory and practice of antimonopoly regulation, the principles of the Russian civil law and the antitrust law, allows to formulate a number of the basic principles and approaches to an assessment of influence of different types of the contract relations on efficiency of use of public resources, welfare of consumers and the competitive environment, the research basis presented in this article also consists in it. Support of the competition is guaranteed by the Constitution of the Russian Federation, is one of bases of the constitutional system of the Russian Federation, and also relevance of a subject of research is confirmed by a constant priority of a state policy it. Development of the competition in economy is a multidimensional task which decision substantially depends on efficiency of carrying out a state policy in a wide range of the directions: from macroeconomic policy, creation of favorable investment climate, including development of financial and tax system, decrease in administrative and infrastructure barriers, before protection of the rights of citizens and national policy. Due to the complexity of a task dynamic landmark approach to work on development of a competition policy in connection with development of contract forms of joint activity of small and large business in the Russian Federation and to formation of the respective directions is necessary. For research by authors of research the following methods are chosen: a statistical method, a reference method to value, a comparative method, system approach, a historical method and a method of the economic analysis of the public relations and the right. Research covers the latest sources in the field reflecting the last economic and standard and legal changes, in particular, them treat: the statistical given, expert estimates, regulations, acts of judicial and administrative practice, scientific publications of economists

  7. Simulated atmospheric disperison of radioactive material released in an urban area

    International Nuclear Information System (INIS)

    Akins, R.E.; Church, H.W.; Tierney, M.S.

    1977-01-01

    A combination of Gaussian plume and particle-in-cell techniques is used to simulate the atmospheric transport and dispersion of a puff release of radioactive material. The release is caused by an accident that is assumed to occur during the shipment of the radioactive material through central New York City. The simulation provides estimates of volumetric and surface concentrations of the dispersed material that are used to predict radiation doses incurred by the City's population in the event of an accidental release. In the simulation, the release point is arbitrary and the material is assumed to be either a gas or fine particles. The Gaussian plume model follows cloud concentrations from the release time until times when transport over distances up to 500 m has been achieved. The released cloud may stabilize at street level or above the mean buildings height; at a street intersection or in the middle of the block. The possibility of the formation of multiple clouds, owing to circumstances of wind flow direction and street geometry, is allowed

  8. A study on the nuclear technology policy

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Maeng Ho; Ham, C. H.; Kim, H. J.; Chung, W. S.; Lee, T. J.; Lee, B. O.; Yun, S. W.; Choi, Y. M.; Eom, T. Y

    1998-01-01

    This study analyzed the major issues as the research activities for the support of establishment and implementation of national policy. The analyses were focused on the recommendations of the responsive direction of national policy in positive and effective manners in accordance with the changes of international nuclear affairs. This study also analyzed the creation of environmental foundation for effective implementation of the national policy and national R and D investment such as securing national consensus and openings of policy information to the public. The major results of the role and position of nuclear policy, trends of nuclear policy and nuclear R and D activities of USA, France, Japan, Asian developing countries etc. and international trends of small- and medium-sized reactor as well as spin-offs of nuclear R and D activities, were analyzed. (author). 66 refs., 27 tabs., 15 figs

  9. Homeless and Policy – Part I

    Centers for Disease Control (CDC) Podcasts

    2010-11-19

    Homelessness in the 21st century is an ongoing problem, increasing due to the country's recent economic downturn, especially in urban areas. This podcast discusses how homelessness impacts policy and what public health professionals can do about it.  Created: 11/19/2010 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) and National Center for Environmental Health (NCEH).   Date Released: 11/19/2010.

  10. Homeless and Policy – Part II

    Centers for Disease Control (CDC) Podcasts

    2010-11-19

    Homelessness in the 21st century is an ongoing problem, increasing due to the country's recent economic downturn, especially in urban areas. This podcast discusses how homelessness impacts policy and what public health professionals can do about it.  Created: 11/19/2010 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) and National Center for Environmental Health (NCEH).   Date Released: 11/19/2010.

  11. Local/regional policies: Acting globally by thinking locally

    International Nuclear Information System (INIS)

    Hillsman, E.L.

    1991-01-01

    Policies to reduce greenhouse gas emissions from present levels will require changes in local and regional decision making as well as decisions made at national and multinational scales. A number of cities and states have taken action to reduce emissions either directly or as a byproduct of solving local problems such as air quality. These initiatives represent a potential resource to be mobilized in national policy. A series of case studies is under way to understand the decision making involved and its implications, and to identify ways that national policy might support and benefit from local efforts. Preliminary results from the first of these case studies indicate that reductions in greenhouse gas emissions may be greater when set as a direct target than when resulting as a byproduct of other local problem solving

  12. Policy for Promotion of Women's Mental Health: Insight from Analysis of Policy on Postnatal Depression in Mexico.

    Science.gov (United States)

    Place, Jean Marie S; Billings, Deborah L; Frongillo, Edward A; Blake, Christine E; Mann, Joshua R; deCastro, Filipa

    2016-03-01

    This article critically examines federal, state and facility-level policies, as well as clinical practice guidelines regarding postnatal depression in Mexico. Thirteen documents including national health plans, national action plans, federal and state laws and regulations, clinical practice guidelines, and public-sector healthcare facility policies were collected and evaluated according to whether they included a statement of intent and/or actions related to the care of women at risk for or experiencing postnatal depression. While postnatal depression is included in several policies in Mexico, it is not addressed in ways that guide actions to manage postnatal depression. Specific direction on postnatal depression in policies would bridge a gap in maternal mental healthcare given that medication, treatment, and timing of interventions is unique in the postpartum context.

  13. Energy poverty policies in the EU: A critical perspective

    International Nuclear Information System (INIS)

    Bouzarovski, Stefan; Petrova, Saska; Sarlamanov, Robert

    2012-01-01

    Once confined to the UK context – where it was struggling to receive political recognition for years – the concept of energy (or fuel) poverty is slowly entering the EU's agenda, where it has crept into a number of regulatory documents and policy proposals. Using evidence gathered from an international workshop and semi-structured interviews with decision-makers, experts and advocacy activists in Brussels and Sofia, this paper explores the adoption of policies aimed at addressing energy poverty within (i) the organisational context of the EU; and (ii) national state institutions in Bulgaria – a member state facing considerable problems at the energy affordability – social inequality nexus. While the former are largely nascent and poorly co-ordinated, the latter have already been implemented de jure to a significant extent. However, many unresolved issues surrounding their de facto implementation remain. At the same time, national policy makers remain largely unaware of the existence of direct energy poverty related initiatives at the EU level. - Highlights: ► This paper explores the adoption of energy poverty policies within the EU and Bulgaria. ► We establish the existence of a range of nascent efforts to address the issue at EU level. ► Bulgaria has been good at implementing EU energy poverty relevant directives. ► However, policy makers speak a different language when it comes to direct energy poverty action.

  14. Artificial intelligence and foreign policy decision-making

    OpenAIRE

    Berkoff, Russ H.

    1997-01-01

    Approved for public release; distribution is unlimited With the advent of a global information society, the US will seek to tap the potential of advanced computing capability to enhance its ability to conduct foreign policy decision making. This thesis explores the potential for improving individual and organizational decision making capabilities by means of artificial intelligence (AI). The use of AI will allow us to take advantage of the plethora of information available to obtain an edg...

  15. Dynamic Systems Modeling in Educational System Design & Policy

    Science.gov (United States)

    Groff, Jennifer Sterling

    2013-01-01

    Over the last several hundred years, local and national educational systems have evolved from relatively simple systems to incredibly complex, interdependent, policy-laden structures, to which many question their value, effectiveness, and direction they are headed. System Dynamics is a field of analysis used to guide policy and system design in…

  16. Simulation experiments on the radial pool growth in gas-releasing melting system

    International Nuclear Information System (INIS)

    Farhadieh, R.; Purviance, R.; Carlson, N.

    1983-01-01

    Following an HCDA, molten core-debris can contact the concrete foundation of the reactor building resulting in a molten UO 2 /concrete interaction and considerable gas release. The released gas can pressurize the containment building potentially leading to radiological releases. Furthermore, directional growth of the molten core-debris pool can reduce the reactor building structural integrity. To implement design changes that insure structural integrity, an understanding of the thermal-hydraulic and mass-transfer process associated with such a growth is most desirable. Owing to the complex nature of the combined heat, mass, and hydrodynamic processes associated with the two-dimensional problem of gas release and melting, the downward and radial penetration problems have been investigated separately. The present experimental study addresses the question of sideward penetration of the molten core debris into a gas-releasing, meltable, miscible solid

  17. A study on the alternative option for nuclear policy

    International Nuclear Information System (INIS)

    Choi, J. W.; Choi, H. J.; Lee, J. Y.; Cho, D. K.; Jeon, K. S.; Park, S. W.; Hahn, D. H.; Yoon, J. S.; Lee, K. S.

    2008-02-01

    Since a decision-making by intuitive judgement under uncertain future conditions can not select an optimum alternative, reaching an agreement for alternatives between experts requires a development of several scientific opinion collection methodologies and performing these methodologies. Therefore, opinion collection for all points related to the nuclear energy, public hearing induction related researches and the acts, procedure, etc. performed in developed countries such as U.S, U.K, France, etc. are reviewed and analyzed in this research. And after the analysis of domestic spent nuclear fuel management plan, Task Force Team composed of experts in several related areas is organized to suggest strategies and directions which are necessary for making a national policy. Beside, Task Force Team selects an optimum technical alternative by the analysis and comparison in depth between these technical alternatives to establish the policy direction. They also established the procedures such as opinion collecting, etc. through policy conference and forum and suggested the technical data related nuclear policy which supports the nuclear policy conference. Results from this research are expected to decrease the trial and error that has been occurred in the present policy-making procedure such as radioactive waste repository related procedure and contribute for socio-cultural stability. Moreover, opinion collection plan for developing a nuclear policy alternative is expected to contribute for making a nuclear policy in the nuclear policy conference so that the nuclear technology will be enhanced more

  18. A study on the alternative option for nuclear policy

    Energy Technology Data Exchange (ETDEWEB)

    Choi, J. W.; Choi, H. J.; Lee, J. Y.; Cho, D. K.; Jeon, K. S.; Park, S. W.; Hahn, D. H.; Yoon, J. S.; Lee, K. S. [KAERI, Daejeon (Korea, Republic of)

    2008-02-15

    Since a decision-making by intuitive judgement under uncertain future conditions can not select an optimum alternative, reaching an agreement for alternatives between experts requires a development of several scientific opinion collection methodologies and performing these methodologies. Therefore, opinion collection for all points related to the nuclear energy, public hearing induction related researches and the acts, procedure, etc. performed in developed countries such as U.S, U.K, France, etc. are reviewed and analyzed in this research. And after the analysis of domestic spent nuclear fuel management plan, Task Force Team composed of experts in several related areas is organized to suggest strategies and directions which are necessary for making a national policy. Beside, Task Force Team selects an optimum technical alternative by the analysis and comparison in depth between these technical alternatives to establish the policy direction. They also established the procedures such as opinion collecting, etc. through policy conference and forum and suggested the technical data related nuclear policy which supports the nuclear policy conference. Results from this research are expected to decrease the trial and error that has been occurred in the present policy-making procedure such as radioactive waste repository related procedure and contribute for socio-cultural stability. Moreover, opinion collection plan for developing a nuclear policy alternative is expected to contribute for making a nuclear policy in the nuclear policy conference so that the nuclear technology will be enhanced more.

  19. Examining the Role of Familial Support During Prison and After Release on Post-Incarceration Mental Health.

    Science.gov (United States)

    Wallace, Danielle; Fahmy, Chantal; Cotton, Lindsy; Jimmons, Charis; McKay, Rachel; Stoffer, Sidney; Syed, Sarah

    2016-01-01

    A significant number of prisoners experience mental health problems, and adequate social support is one way that facilitates better mental health. Yet, by being incarcerated, social support, particularly family support, is likely to be strained or even negative. In this study, we examine whether familial support--either positive or negative--in-prison and after release affects mental health outcomes post-release. Using the Serious and Violent Offender Reentry Initiative (SVORI) dataset, we regress post-release mental health on in-prison familial support, post-incarceration familial support, and changes in familial support. We find that while in-prison family support does not affect mental health, post-release familial support does. Also, experiencing an increase in negative familial support is associated with lower post-incarceration mental health. We conclude with a discussion of policies which may facilitate better familial support environments. © The Author(s) 2014.

  20. 29 CFR 783.37 - Enforcement policy for non-seaman's work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Enforcement policy for non-seaman's work. 783.37 Section... policy for non-seaman's work. In the enforcement of the Act, an employee will be regarded as “employed as... STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS APPLICATION OF THE FAIR...

  1. 48 CFR 702.170-17 - Automated Directives System.

    Science.gov (United States)

    2010-10-01

    .... “Automated Directives System” (“ADS”) sets forth the Agency's policies and essential procedures, as well as supplementary informational references. It contains six functional series, interim policy updates, valid USAID handbook chapters, a resource library, and a glossary. References to “ADS” throughout this chapter 7 are...

  2. Interactions management in environmental policy

    NARCIS (Netherlands)

    Krozer, Yoram; Franco Garcia, Maria Maria; Micallef, David

    2013-01-01

    Purpose: The paper aims to address regulator-management interactions in environmental policy with reference to direct regulations, social regulations and market-based regulation. Design/methodology/approach: Revision of literature to identify the European Union regulations for companies producing

  3. Federal Republic of Germany: family planning, family policy and demographic policy.

    Science.gov (United States)

    Zuhlke, W

    1989-01-01

    Decades of social change in West Germany and the emergence of an ideology that stresses individualism have altered dramatically procreative behavioral patterns. At present, West Germany is characterized by a low marriage rate (6.1/1000 in 1986), declining fertility (10.3 birth/1000), rising divorce rates (20.1/1000), and increases in the proportion of single-person households (34%). The relationship between family planning, family policy, and demographic policy is unclear and changing. Family planning practice is viewed as a part of comprehensive life planning and is based on factors such as partnership or marital status, sex roles, the conflict between working in the home and having a career, consumer aspirations, and housing conditions. The Government's family policy includes the following components: child benefits, tax relief on children, tax splitting arrangements for married couples, childcare allowance, parental leave, student grants, tax deductions for domiciliary professional help and nursing assistance, and the provision of daycare. Thus, West Germany's family policy is directed more at encouraging and facilitating parenthood and family life than at a setting demographic goals. There is no evidence, however, that such measures will be successful and divergent influences of other policy areas are often more compelling. Nor is there any way to quantify the fertility-costing impact of individual family policy measures. The indistinct nature of family planning policy in West Germany mirrors political differences between the current coalition government, which maintains a traditional view of the family, and the opposition Social-Democratic and Green Parties, which question whether the equality of men and women can be achieved in the context of old family structures.

  4. 29 CFR 786.150 - Enforcement policy concerning performance of nonexempt work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Enforcement policy concerning performance of nonexempt work..., DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS MISCELLANEOUS EXEMPTIONS Employers Subject to Part 1 of Interstate Commerce Act § 786.150 Enforcement policy...

  5. How trust and emotions influence policy acceptance: The case of the Irish water charges.

    Science.gov (United States)

    Rodriguez-Sanchez, Carla; Schuitema, Geertje; Claudy, Marius; Sancho-Esper, Franco

    2018-02-01

    The introduction of new policies can evoke strong emotional reactions by the public. Yet, social-psychological research has paid little attention to affective determinants of individual-level policy acceptance. Building on recent theoretical and empirical advances around emotions and decision-making, we evaluate how people's trust and integral emotions function as important antecedents of cognitive evaluations, and subsequent acceptance of policies. We test our hypotheses within a sample of Irish citizens (n = 505), who were subject to the introduction of water charges in 2015. In line with our hypotheses, results show that general trust in government shapes emotions regarding water charges, which in turn, directly and via expected costs and benefits, influence policy acceptance. Additionally, we find that negative emotions have a larger direct effect on policy acceptance than positive emotions. Specifically, 'anger' was the main negative emotion that influenced the acceptance of the water charge. We conclude by discussing directions for future research around emotions and policy acceptance. © 2018 The British Psychological Society.

  6. Completion of decommissioning: Monitoring for site release and license termination

    International Nuclear Information System (INIS)

    Boing, L.E.

    1997-01-01

    To request termination of a license upon completion of dismantling or decommissioning activities, documenting any residual radioactivity to show that the levels are environmentally acceptable will be necessary. When the regulators approve the decommissioning plan, they establish what the release criteria for the decommissioned site will be at the time of the site release and license termination. The criteria are numeric guidelines for direct radiation in soils and on surfaces. If the regulatory body finds that the measured on-site values are below the guidelines, the site will be acceptable for unrestricted release (no radiological controls or future use). If areas are found above those values, more decontamination or cleanup of these areas may be required unless the regulatory body grants an exemption

  7. Renewable Energy Policy Fact sheet - Finland

    International Nuclear Information System (INIS)

    2017-09-01

    The EurObserv'ER policy profiles give a snapshot of the renewable energy policy in the EU Member States. By 2014 Finland already surpassed its 2020 target for renewable energy use under the 2009 EU Renewable Energy Directive. The current feed-in premium system will be discontinued and is expected to be replaced with a competitive technology-neutral tendering scheme, in line with the requirements set in the 2014 State Aid guidelines

  8. Hurricane Harvey, Houston's Petrochemical Industry, and US Chemical Safety Policy: Impacts to Environmental Justice Communities

    Science.gov (United States)

    Goldman, G. T.; Johnson, C.; Gutierrez, A.; Declet-Barreto, J.; Berman, E.; Bergman, A.

    2017-12-01

    When Hurricane Harvey made landfall outside Houston, Texas, the storm's wind speeds and unprecedented precipitation caused significant damage to the region's petrochemical infrastructure. Most notably, the company Arkema's Crosby facility suffered a power failure that led to explosions and incineration of six of its peroxide tanks. Chemicals released into the air from the explosions sent 15 emergency responders to the hospital with severe respiratory conditions and led to the evacuation of hundreds of surrounding households. Other petrochemical facilities faced other damages that resulted in unsafe and acute chemical releases into the air and water. What impacts did such chemical disasters have on the surrounding communities and emergency responders during Harvey's aftermath? What steps might companies have taken to prevent such chemical releases? And what chemical safety policies might have ensured that such disaster risks were mitigated? In this talk we will report on a survey of the extent of damage to Houston's oil and gas infrastructure and related chemical releases and discuss the role of federal chemical safety policy in preventing and mitigating the potential for such risks for future storms and other extreme weather and climate events. We will also discuss how these chemical disasters created acute toxics exposures on environmental justice communities already overburdened with chronic exposures from the petrochemical industry.

  9. Drug release control and system understanding of sucrose esters matrix tablets by artificial neural networks.

    Science.gov (United States)

    Chansanroj, Krisanin; Petrović, Jelena; Ibrić, Svetlana; Betz, Gabriele

    2011-10-09

    Artificial neural networks (ANNs) were applied for system understanding and prediction of drug release properties from direct compacted matrix tablets using sucrose esters (SEs) as matrix-forming agents for controlled release of a highly water soluble drug, metoprolol tartrate. Complexity of the system was presented through the effects of SE concentration and tablet porosity at various hydrophilic-lipophilic balance (HLB) values of SEs ranging from 0 to 16. Both effects contributed to release behaviors especially in the system containing hydrophilic SEs where swelling phenomena occurred. A self-organizing map neural network (SOM) was applied for visualizing interrelation among the variables and multilayer perceptron neural networks (MLPs) were employed to generalize the system and predict the drug release properties based on HLB value and concentration of SEs and tablet properties, i.e., tablet porosity, volume and tensile strength. Accurate prediction was obtained after systematically optimizing network performance based on learning algorithm of MLP. Drug release was mainly attributed to the effects of SEs, tablet volume and tensile strength in multi-dimensional interrelation whereas tablet porosity gave a small impact. Ability of system generalization and accurate prediction of the drug release properties proves the validity of SOM and MLPs for the formulation modeling of direct compacted matrix tablets containing controlled release agents of different material properties. Copyright © 2011 Elsevier B.V. All rights reserved.

  10. Policy on stable iodine prophylaxis following nuclear reactor accidents (1989)

    International Nuclear Information System (INIS)

    1989-09-01

    This policy considers the alleviation of possible hazards that may arise from any radioiodines inhaled from a plume of fission products emanating from a nuclear reactor accident. Such a nuclear reactor may be land or ship-based. In any accident that releases radioiodines to the environment, one countermeasure that may need to be considered to reduce the effect of inhalation of radioiodines by persons downwind of the point of release is to provide those persons with tablets containing stable iodine. Both potassium iodide (KI) and potassium iodate (KIO 3 ) are recommended as effective prophylactics tablets for this purpose in Australia. Action levels, doses and contraindicatories are briefly outlined

  11. THE INFLUENCES OF INFLATION ON THE MONETARY POLICY INTEREST

    Directory of Open Access Journals (Sweden)

    Popa Coralia Emilia

    2012-12-01

    Full Text Available In the context of sovereign debt crisis in Europe, a crisis entirely felt also in the direct relation between credit institutions, the National Bank of Romania (NBR adopted a monetary policy strategy meant to determine the reinforcement of its image, by initiating in the autumn of 2011 a new series of reduction of the monetary policy interest rate and implicitly the appropriate resizing of liquidity conditions. By increasing the role of liquidity adjustment, the European Central Bank (ECB succeeded to determine in the money market the decrease of interbank rate interests under the interest rate level of monetary policy. The direct inflation targeting strategy used by the European Central Bank in applying its monetary policy has the first criterion of implementation the expression of inflation target in terms of „headline inflation” (consumer price index - CPI given that the economic market in Romania is familiar with this indicator. Also, the main criterion considered by the investment segment of the market to achieve capital infusions in economic transactions is represented by the consumer price index, this one ensuring the necessary transparency related to the effects of inflation phenomenon. A strong argument supporting the use of consumer price index in monetary policy is represented by its upward flexibility towards the limited effectiveness of monetary aggregates in sizing inflationary anticipations. The downward slope of inflation phenomenon, in whose depreciation the evolution of consumer price index, whose positive trend surprised the European Central Bank, played a significant role, determined adjustments in the monetary policy strategy of the National Bank of Romania and at the same time the achievement of the inflationary target proposed with a direct effect on the monetary policy interest rate. The same measure to reduce the key interest rate is outlined in the monetary policy of the European Central Bank and it is

  12. Dose estimation models for environmental tritium released from fusion facilities

    International Nuclear Information System (INIS)

    Murata, Mikio

    1993-01-01

    Various mathematical models are being developed to predict the behavior of HT released to the natural environment and their consequent impact. This report outlines models and the major findings of HT field release studies in France and Canada. The models are constructed to incorporate the key processes thought to be responsible for the formation of atmospheric HTO from a release of HT. It has been established from the experiments that HT oxidized in surface soil is incorporated almost entirely into soil water as HTO. This tritium may be reemitted to the atmosphere in the form of HTO through exchange of soil and atmospheric moisture as well as through the bulk water mass flux from the soil the atmosphere due to evaporation and transpiration. The direct conversion of HT to HTO in air and direct uptake of HT by vegetation are expected to be negligible for the time and space scales of interest in considering short duration releases. HTO emitted to the atmosphere is can further exchange with soil and vegetation water. Validation of these models against experimental data is conducted to demonstrate their credibility. It may be concluded that further laboratory and field works are needed in order to develop a sufficiently good understanding of the dependence of the key processes on environmental factors (including diurnal cycling and seasonality) to allow the rates of the processes to be predicted from a knowledge of environmental conditions. (author)

  13. Regime change and public policy: the political and macro-economic decision-making of Spanish energy policy

    Energy Technology Data Exchange (ETDEWEB)

    Lancaster, T.D.

    1983-01-01

    This dissertation examines the effects of peaceful regime change on public policy-making. Spain's National Energy Plan (PEN) in particular, and energy planning in general, constitute a critical policy issue which permits direct comparison of decision-making across regime change from the Franco dictatorship to the present constitutional monarchy. The research reveals that the nature of the political coalition underlying Spain's regime change accounts of the lack of significant change in policy-making processes in this particular policy issue. This thesis develops a two-pronged argument to explain the absence of significant policy change. The first is based on a general view of the Franco regime's and the democratic system's coalitional support. In each, three major political forces are seen as central: the military, business, and labor. One of these, business, is seen as being pivotal in the regime transition. Business' pivotal position, it is argued, has permitted a defence of a national energy policy beneficial to its economic interests in energy. The argument's second part focuses on the binding constraint on policy outcomes imposed by private interests in state planning and the generally non-binding nature of oppositional party policy proposals and public opinion.

  14. SU-F-19A-08: Optimal Time Release Schedule of In-Situ Drug Release During Permanent Prostate Brachytherapy

    International Nuclear Information System (INIS)

    Cormack, R; Ngwa, W; Makrigiorgos, G; Tangutoori, S; Rajiv, K; Sridhar, S

    2014-01-01

    Purpose: Permanent prostate brachytherapy spacers can be used to deliver sustained doses of radiosentitizing drug directly to the target, in order to enhance the radiation effect. Implantable nanoplatforms for chemo-radiation therapy (INCeRTs) have a maximum drug capacity and can be engineered to control the drug release schedule. The optimal schedule for sensitization during continuous low dose rate irradiation is unknown. This work studies the optimal release schedule of drug for both traditional sensitizers, and those that work by suppressing DNA repair processes. Methods: Six brachytherapy treatment plans were used to model the anatomy, implant geometry and calculate the spatial distribution of radiation dose and drug concentrations for a range of drug diffusion parameters. Three state partial differential equations (cells healthy, damaged or dead) modeled the effect of continuous radiation (radiosensitivities α,β) and cellular repair (time tr) on a cell population. Radiosensitization was modeled as concentration dependent change in α,β or tr which with variable duration under the constraint of fixed total drug release. Average cell kill was used to measure effectiveness. Sensitization by means of both enhanced damage and reduced repair were studied. Results: Optimal release duration is dependent on the concentration of radiosensitizer compared to the saturation concentration (csat) above which additional sensitization does not occur. Long duration drug release when enhancing α or β maximizes cell death when drug concentrations are generally over csat. Short term release is optimal for concentrations below saturation. Sensitization by suppressing repair has a similar though less distinct trend that is more affected by the radiation dose distribution. Conclusion: Models of sustained local radiosensitization show potential to increase the effectiveness of radiation in permanent prostate brachytherapy. INCeRTs with high drug capacity produce the greatest

  15. Sustained-release progesterone vaginal suppositories 1--development of sustained-release granule--.

    Science.gov (United States)

    Nakayama, Ayako; Sunada, Hisakazu; Okamoto, Hirokazu; Furuhashi, Kaoru; Ohno, Yukiko; Ito, Mikio

    2009-02-01

    Progesterone (P) is an important hormone for the establishment of pregnancy, and its administration is useful for luteal insufficiency. Considering the problems of commercially available oral and injection drugs, hospital-formulated vaginal suppositories are clinically used. However, since the half-life of P suppositories is short, it is difficult to maintain its constant blood concentration. To sustain drug efficacy and prevent side-effects, we are attempting to develop sustained-release suppositories by examining the degree of sustained-release of active ingredients. In this study, we examined the combinations of granulation methods and release systems for the preparation of sustained-release granules of P, and produced 13 types of sustained-release granules. We also examined the diameter, content, and dissolution of each type of granules, and confirmed that the sustained-release of all types of granules was satisfactory. Among the sustained-release granules, we selected granules with a content and a degree of sustained-release suitable for sustained-release suppositories.

  16. Re-examination of sea lamprey control policies for the St. Marys River: Completion of an adaptive management cycle

    Science.gov (United States)

    Jones, Michael L.; Brenden, Travis O.; Irwin, Brian J.

    2015-01-01

    The St. Marys River (SMR) historically has been a major producer of sea lampreys (Petromyzon marinus) in the Laurentian Great Lakes. In the early 2000s, a decision analysis (DA) project was conducted to evaluate sea lamprey control policies for the SMR; this project suggested that an integrated policy of trapping, sterile male releases, and Bayluscide treatment was the most cost-effective policy. Further, it concluded that formal assessment of larval sea lamprey abundance and distribution in the SMR would be valuable for future evaluation of control strategies. We updated this earlier analysis, adding information from annual larval assessments conducted since 1999 and evaluating additional control policies. Bayluscide treatments continued to be critical for sea lamprey control, but high recruitment compensation minimized the effectiveness of trapping and sterile male release under current feasible ranges. Because Bayluscide control is costly, development of strategies to enhance trapping success remains a priority. This study illustrates benefits of an adaptive management cycle, wherein models inform decisions, are updated based on learning achieved from those decisions, and ultimately inform future decisions.

  17. Policy Impact on the Chinese Stock Market: From the 1994 Bailout Policies to the 2015 Shanghai-Hong Kong Stock Connect

    Directory of Open Access Journals (Sweden)

    Yang-Chao Wang

    2017-01-01

    Full Text Available From the 1994 bailout policies to the 2015 Shanghai-Hong Kong Stock Connect, the policy impact on the Chinese stock market has changed over time. By May 2015, global investors can directly invest in a more legalized and normalized Chinese stock market, whereas they are still concerned about the policy-oriented market and its attendant risks. In this study, we employ the family of GARCH models to investigate the structural changes in risks with the implementation of a series of policies. Our results show that although many policies improve or stabilize the stock market, certain policies lead to substantial volatility. Among them, macro-control policies and transaction cost adjustments are a double-edged sword, which should be used with caution. Furthermore, with opening-up policies being launched recently, the Chinese stock market has entered a new stage in which it affects international capital markets. However, the increased risks, which may result in a sharp turnaround, cause worry.

  18. Macroprudential policies on banking system

    Directory of Open Access Journals (Sweden)

    Ionuţ Mircea

    2015-05-01

    Full Text Available The macro-prudential tool kit deals with those risks that contributed to the outbreak of the last economic crisis or materialized during it, namely the excessive credit growth, the excessive price assets growth driven by the credit growth, the excessive increase in leverage, the liquidity risk, the volatile capital flows and foreign currency lending. It can be argued that macro-prudential policies underestimated the systemic risks mentioned, although they were better positioned than other policies aimed at financial stability. The impact of macro-prudential policy is difficult to be determined, because is usually applied simultaneously and in the same direction with other macroeconomic policies. Thus, it is necessary a better coordination of policies and a better calibration of instruments in order to get a quick and effective response during their implementation. These must be in line with national specificities and the risks identified. Until the new macro-prudential tools introduced by Basel III will prove their effectiveness, the issue of finding proper tools is still open.

  19. South African HIV self-testing policy and guidance considerations

    Directory of Open Access Journals (Sweden)

    Francois Venter

    2017-10-01

    Full Text Available The gap in HIV testing remains significant and new modalities such as HIV self-testing (HIVST have been recommended to reach key and under-tested populations. In December 2016, the World Health Organization (WHO released the Guidelines on HIV Self-Testing and Partner Notification: A Supplement to the Consolidated Guidelines on HIV Testing Services (HTS and urged member countries to develop HIVST policy and regulatory frameworks. In South Africa, HIVST was included as a supplementary strategy in the National HIV Testing Services Policy in 2016, and recently, guidelines for HIVST were included in the South African National Strategic Plan for HIV, sexually transmitted infections and tuberculosis 2017–2022. This document serves as an additional guidance for the National HIV Testing Services Policy 2016, with specific focus on HIVST. It is intended for policy advocates, clinical and non-clinical HTS providers, health facility managers and healthcare providers in private and public health facilities, non-governmental, community-based and faith-based organisations involved in HTS and outreach, device manufacturers, workplace programmes and institutes of higher education.

  20. Are national policies on global health in fact national policies on global health governance? A comparison of policy designs from Norway and Switzerland.

    Science.gov (United States)

    Jones, Catherine M; Clavier, Carole; Potvin, Louise

    2017-01-01

    Since the signing of the Oslo Ministerial Declaration in 2007, the idea that foreign policy formulation should include health considerations has gained traction on the United Nations agenda as evidenced by annual General Assembly resolutions on global health and foreign policy. The adoption of national policies on global health (NPGH) is one way that some member states integrate health and foreign policymaking. This paper explores what these policies intend to do and how countries plan to do it. Using a most similar systems design, we carried out a comparative study of two policy documents formally adopted in 2012. We conducted a directed qualitative content analysis of the Norwegian White Paper on Global health in foreign and development policy and the Swiss Health Foreign Policy using Schneider and Ingram's policy design framework. After replicating analysis methods for each document, we analysed them side by side to explore the commonalities and differences across elements of NPGH design. Analyses indicate that NPGH expect to influence change outside their borders. Targeting the international level, they aim to affect policy venues, multilateral partnerships and international institutions. Instruments for supporting desired changes are primarily those of health diplomacy, proposed as a tool for negotiating interests and objectives for global health between multiple sectors, used internally in Switzerland and externally in Norway. Findings suggest that NPGH designs contribute to constructing the global health governance system by identifying it as a policy target, and policy instruments may elude the health sector actors unless implementation rules explicitly include them. Research should explore how future NPGH designs may construct different kinds of targets as politicised groups of actors on which national governments seek to exercise influence for global health decision-making.

  1. Are national policies on global health in fact national policies on global health governance? A comparison of policy designs from Norway and Switzerland

    Science.gov (United States)

    Clavier, Carole; Potvin, Louise

    2017-01-01

    Background Since the signing of the Oslo Ministerial Declaration in 2007, the idea that foreign policy formulation should include health considerations has gained traction on the United Nations agenda as evidenced by annual General Assembly resolutions on global health and foreign policy. The adoption of national policies on global health (NPGH) is one way that some member states integrate health and foreign policymaking. This paper explores what these policies intend to do and how countries plan to do it. Methods Using a most similar systems design, we carried out a comparative study of two policy documents formally adopted in 2012. We conducted a directed qualitative content analysis of the Norwegian White Paper on Global health in foreign and development policy and the Swiss Health Foreign Policy using Schneider and Ingram's policy design framework. After replicating analysis methods for each document, we analysed them side by side to explore the commonalities and differences across elements of NPGH design. Results Analyses indicate that NPGH expect to influence change outside their borders. Targeting the international level, they aim to affect policy venues, multilateral partnerships and international institutions. Instruments for supporting desired changes are primarily those of health diplomacy, proposed as a tool for negotiating interests and objectives for global health between multiple sectors, used internally in Switzerland and externally in Norway. Conclusion Findings suggest that NPGH designs contribute to constructing the global health governance system by identifying it as a policy target, and policy instruments may elude the health sector actors unless implementation rules explicitly include them. Research should explore how future NPGH designs may construct different kinds of targets as politicised groups of actors on which national governments seek to exercise influence for global health decision-making. PMID:28589007

  2. Foreign direct investment in China

    OpenAIRE

    Bredero, Q.S.

    2007-01-01

    Foreign Direct Investment in China is one of the most comprehensive studies of FDI in China and provides a remarkable background of information on the evolution of China’s FDI policies over the last 30 years.

  3. Participation in European water policy

    NARCIS (Netherlands)

    J.A. van Ast (Jacko); S.P. Boot (Sander Paul)

    2003-01-01

    textabstractThis paper considers the possibilities for interactive policy-making in European water management. In the new European Water Framework Directive, public information and consultation are major elements in the procedure (process) that leads to River Basin Management Plans. In general,

  4. Agricultural intensification and policy interventions

    NARCIS (Netherlands)

    Falconnier, Gatien N.; Descheemaeker, Katrien; Traore, Bouba; Bayoko, Arouna; Giller, Ken E.

    2018-01-01

    Assessing how livelihoods in rural sub-Saharan Africa might change given future trends in socio-economic and biophysical conditions helps to identify and direct effective efforts towards poverty reduction. Based on existing literature, hypothetical changes in farmer practices and policy

  5. Design of generic coal conversion facilities: Process release---Direct coal liquefaction

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    The direct liquefaction portion of the PETC generic direct coal liquefaction process development unit (PDU) is being designed to provide maximum operating flexibility. The PDU design will permit catalytic and non-catalytic liquefaction concepts to be investigated at their proof-of-the-concept stages before any larger scale operations are attempted. The principal variations from concept to concept are reactor configurations and types. These include thermal reactor, ebullating bed reactor, slurry phase reactor and fixed bed reactor, as well as different types of catalyst. All of these operating modes are necessary to define and identify the optimum process conditions and configurations for determining improved economical liquefaction technology.

  6. ECONOMIC EFFECTS OF ENERGY POLICIES

    Directory of Open Access Journals (Sweden)

    Mihaela ȘTEȚ

    2014-12-01

    Full Text Available This paper highlights some of the issues raised by the implementation of energy policies and the fiscal measures in the energy sector and it aims to identify the impact of energy policies at regional level. It is emphasized, along with the environmental impact of the use of renewable resources and economic and social effects on sustainable regional development which can generate state intervention through direct and indirect, financial and non-financial instruments. Given the complex energy profile of Romania, the paper reveals also, the problems that have had to face in the last two decades and the impact of energy policies of Romanian governments. The research is based on an analysis of statistics, publications in energy sector, as well as primary and specific legislation.

  7. Evaluating a traditional medicine policy in South Africa: phase 1 development of a policy assessment tool

    Directory of Open Access Journals (Sweden)

    Georgios Gavriilidis

    2012-05-01

    Full Text Available Background: Policies that empower individuals and communities may be appropriate for public health, and more broadly. Simple, transparent and acceptable tools are therefore required to evaluate policies from an empowerment perspective. In 2008, the South African Department of Health (DOHSA drafted a policy to endorse the integration of African Traditional Medicine (ATM into the public health sector, following the World Health Organization's (WHO long-standing directives. Objective: The purpose of this study is to critically analyze this policy using a novel evaluation tool. Design: A 12-point ‘Policy Empowerment Index’ (PEI is introduced, and used to classify and score the policy according to five theoretical policy types. The evaluation was based on a stepwise review and associated publications: policy drafts, policy statements and news announcements. Results: According to the assessment tool, the ATM policy was marginally ‘supportive’ of constituent empowerment, although several ‘directive’ features were also observed. The importance of ATM to SA's communities and the promotion of education, employment, entrepreneurship and peripheral resource mobilization were the main empowering elements. Centralised conception, planning and implementation, the absence of provisions for local adaptations and the authoritative legislation context were sub-optimal features. Conclusions: South Africa's ATM legislation may need to further involve communities in policy design and implementation to capitalise upon the broader benefits of community empowerment. However, the iterative nature of method and evaluation is important. Indeed, they are proposed as points to initiate participatory development, and improve policy evaluation . Such instruments can empower constituents in the political process.

  8. Discussion: European Commission policy

    International Nuclear Information System (INIS)

    Coldwell, R.

    1993-01-01

    This paper documents the debate which arose following two papers presented to a seminar run by the Centre for the Study of Regulated Industries, on 11th November 1992, on European Commission (EC) energy policies. The issues raised cover how an internal market for electricity and natural gas will be implemented under a proposed EC directive, bearing in mind the level of opposition from a number of Member States. How this Directive will apply to vertically integrated structures, such as Scottish Electricity Industry, is also considered. (UK)

  9. Big ideas: innovation policy

    OpenAIRE

    John Van Reenen

    2011-01-01

    In the last CentrePiece, John Van Reenen stressed the importance of competition and labour market flexibility for productivity growth. His latest in CEP's 'big ideas' series describes the impact of research on how policy-makers can influence innovation more directly - through tax credits for business spending on research and development.

  10. Characterization of unsaturated fatty acid sustained-release microspheres for long-term algal inhibition.

    Science.gov (United States)

    Ni, Lixiao; Jie, Xiaoting; Wang, Peifang; Li, Shiyin; Hu, Shuzhen; Li, Yiping; Li, Yong; Acharya, Kumud

    2015-02-01

    The unsaturated fatty acid (linoleic acid) sustained-release microspheres were prepared with linoleic acid (LA) using alginate-chitosan microcapsule technology. These LA sustained-release microspheres had a high encapsulation efficiency (up to 62%) tested by high performance liquid chromatography with a photo diode array. The dry microspheres were characterized by a scanning electron microscope, X-ray diffraction measurement, dynamic thermogravimetric analysis and Fourier transform infrared spectral analysis. The results of characterization showed that the microspheres had good thermal stability (decomposition temperature of 236°C), stable and temperature independent release properties (release time of more than 40 d). Compared to direct dosing of LA, LA sustained-released microspheres could inhibit Microcystis aeruginosa growth to the non-growth state. The results of this study suggested that the LA sustained-release microspheres may be a potential candidate for algal inhibition. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. The law enforcement approach to combating terrorism : an analysis of US policy

    OpenAIRE

    Nagel, William C.

    2002-01-01

    Approved for public release; distribution is unlimited. This thesis examines the US policy for combating terrorism from 1988 to 2000 using five case studies; the bombing of Pan Am flight 103, the bombing of the World Trade Center in 1993, the bombing of the US barracks in Saudi Arabia in 1996, the bombings of two US embassies in Africa in 1998 and the bombing of the USS Cole in 2000. The thesis begins by outlining the minimum requirements for a counter-terrorism policy. They are; that a po...

  12. Release Report for Building Debris for TA-21 Sewage Treatment Facility

    Energy Technology Data Exchange (ETDEWEB)

    Whicker, Jeffrey Jay [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Gillis, Jessica [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ruedig, Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-03

    ENV-ES finds that the materials associated with TA-21 Buildings 227 (superstructure only), and 229 (see Figure 1) meet the criteria for unrestricted release to the public for recycle or as sanitary/commercial waste. The interior and exterior of the metal shed, building 387, passed the release criteria collectively; however, results from the roof of the structure were above reference background measurements. Waste management should be consulted for waste disposition options for the roofing metal. These findings are consistent with the requirements of DOE Order 458.1 “Radiation Protection of the Public and the Environment” and LANL Policy 412 “Environmental Radiation Protection.” Sampling and data analysis, as described in this report, were sufficient to meet measurement objectives under the Multi-Agency Radiation Survey and Assessment of Materials and Equipment (MARSAME) manual (2009).

  13. An interagency space nuclear propulsion safety policy for SEI - Issues and discussion

    Science.gov (United States)

    Marshall, A. C.; Sawyer, J. C., Jr.

    1991-01-01

    An interagency Nuclear Safety Policy Working Group (NSPWG) was chartered to recommend nuclear safety policy, requirements, and guidelines for the Space Exploration Initiative nuclear propulsion program to facilitate the implementation of mission planning and conceptual design studies. The NSPWG developed a top level policy to provide the guiding principles for the development and implementation of the nuclear propulsion safety program and the development of Safety Functional Requirements. In addition, the NSPWG reviewed safety issues for nuclear propulsion and recommended top level safety requirements and guidelines to address these issues. Safety topics include reactor start-up, inadvertent criticality, radiological release and exposure, disposal, entry, safeguards, risk/reliability, operational safety, ground testing, and other considerations. In this paper the emphasis is placed on the safety policy and the issues and considerations that are addressed by the NSPWG recommendations.

  14. Consumer information or direct product experience? Alternative information policies and their effects on consumer acceptance of GM foods

    DEFF Research Database (Denmark)

    Scholderer, Joachim

    an informed purchase decision. Unfortunately, things are not that simple. Previous research has shown that Europeans already hold firm negative attitudes to GM foods. These attitudes are not based on risk-benefit evaluations of particular products. Rather, they seem to be a function of consumers? general......) consumers can be given the opportunity to evaluate GM products on the basis of direct experience, i.e. after the products have been launched. The first approach represents the transparency/precaution policy that was actually adopted in Europe, whilst the second one was dismissed after confrontations arose...... between different stakeholder groups in connection with Nestle's "Butterfinger" launch in 1998. Both approaches would have to compete against a strong network of pre-existing consumer attitudes, but surprisingly, neither of them has ever been experimentally tested on a broad scale. Two experiments...

  15. Public policy, rationality and reason

    Directory of Open Access Journals (Sweden)

    Rodolfo Canto Sáenz

    2015-07-01

    Full Text Available This work suggests the incorporation of practical reason in the design, implementation and evaluation of public policies, alongside instrumental rationality. It takes two proposals that today point in this direction: Rawls distinction between reasonable (practical reason and rational (instrumental reason and what this author calls the CI Procedure (categorical imperative procedure and Habermas model of deliberative democracy. The main conclusion is that the analysis of public policies can not be limited to rather narrow limits of science, but requires the contribution of political and moral philosophy.

  16. Evidence for endogenous opioid release in the amygdala during positive emotion.

    Science.gov (United States)

    Koepp, M J; Hammers, A; Lawrence, A D; Asselin, M C; Grasby, P M; Bench, C J

    2009-01-01

    Endogenous opioid release has been linked to relief from aversive emotional memories, thereby promoting a euphoric state and subsequent interactions towards social stimuli resulting in the formation of social preferences. However, this theory remains controversial. Using positron emission tomography and [(11)C]diprenorphine (DPN) in healthy volunteers, we found significantly reduced DPN binding to opioid receptor in the hippocampus during positive mood induction compared to neutral mood. Furthermore, the magnitude of positive mood change correlated negatively with DPN binding in the amygdala bilaterally. Our finding of reduced DPN binding is consistent with increased release of endogenous opioids, providing direct evidence that localised release of endogenous opioids is involved in the regulation of positive emotion in humans.

  17. DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN

    Directory of Open Access Journals (Sweden)

    K. H. Janardhana

    2015-07-01

    Full Text Available Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug. Baclofen was chosen because of its poor water solubility and short elimination half-life. Poloxamer 188 and PEG 6000 were used as solid dispersion carrier. Free flowing solid dispersion granules were prepared by adsorbing the melt of the drug and carriers onto the surface of an adsorbent, Carbopol 934P followed by direct compression with HPMC K4M and HPMC K100 to obtain an solid dispersion loaded sustained release tablets. FTIR studies confirmed that the compatibility of drug and carriers. Differential scanning calorimetry (DSC and X-ray diffraction (XRD revealed partially amorphous structures of the drug in solid dispersion granules. The solid dispersion granules dissolved completely within 30 min, which was much faster than that of pure drug baclofen. The sustained release of baclofen from the solid dispersion containing tablet was achieved for 2 h in gastric fluid (pH 1.2 and for up to 10 h in intestinal fluid (pH 6.8. A combination of solid dispersion techniques using adsorption and sustained release concepts is a promising approach to control the release rate of poorly water-soluble drugs.

  18. DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN

    Directory of Open Access Journals (Sweden)

    K. H. Janardhana

    2013-12-01

    Full Text Available Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug. Baclofen was chosen because of its poor water solubility and short elimination half-life. Poloxamer 188 and PEG 6000 were used as solid dispersion carrier. Free flowing solid dispersion granules were prepared by adsorbing the melt of the drug and carriers onto the surface of an adsorbent, Carbopol 934P followed by direct compression with HPMC K4M and HPMC K100 to obtain an solid dispersion loaded sustained release tablets. FTIR studies confirmed that the compatibility of drug and carriers. Differential scanning calorimetry (DSC and X-ray diffraction (XRD revealed partially amorphous structures of the drug in solid dispersion granules. The solid dispersion granules dissolved completely within 30 min, which was much faster than that of pure drug baclofen. The sustained release of baclofen from the solid dispersion containing tablet was achieved for 2 h in gastric fluid (pH 1.2 and for up to 10 h in intestinal fluid (pH 6.8. A combination of solid dispersion techniques using adsorption and sustained release concepts is a promising approach to control the release rate of poorly water-soluble drugs.

  19. Government Policies for Corporate Social Responsibility in Europe:

    DEFF Research Database (Denmark)

    Knudsen, Jette Steen; Moon, Jeremy; Slager, Rieneke

    2015-01-01

    This paper analyses policies of 22 European Union member governments, designed to encourage corporate social responsibility (CSR) between 2000 and 2011. It categorises these policies by their regulatory strength and identifies the range of issues to which CSR policies are directed. The paper argues...... that Northern European, Scandinavian and UK governments are reconstructing their respective institutional structures to embed CSR concerns more explicitly therein. It concludes that these government CSR initiatives are converging, particularly around their increased regulatory strength and the broadening...

  20. Radiological effluents released from US continental tests, 1961 through 1992. Revision 1

    International Nuclear Information System (INIS)

    Schoengold, C.R.; DeMarre, M.E.; Kirkwood, E.M.

    1996-08-01

    This report documents all continental tests from September 15, 1961, through September 23, 1992, from which radioactive effluents were released. The report includes both updated information previously published in the publicly available May, 1990 report, DOE/NV-317, ''Radiological Effluents Released from Announced US Continental Tests 1961 through 1988'', and effluent release information on formerly unannounced tests. General information provided for each test includes the date, time, location, type of test, sponsoring laboratory and/or agency or other sponsor, depth of burial, purpose, yield or yield range, extent of release (onsite only or offsite), and category of release (detonation-time versus post-test operations). Where a test with simultaneous detonations is listed, location, depth of burial and yield information are given for each detonation if applicable, as well as the specific source of the release. A summary of each release incident by type of release is included. For a detonation-time release, the effluent curies are expressed at R+12 hours. For a controlled releases from tunnel-tests, the effluent curies are expressed at both time of release and at R+12 hours. All other types are listed at the time of the release. In addition, a qualitative statement of the isotopes in the effluent is included for detonation-time and controlled releases and a quantitative listing is included for all other types. Offsite release information includes the cloud direction, the maximum activity detected in the air offsite, the maximum gamma exposure rate detected offsite, the maximum iodine level detected offsite, and the maximum distance radiation was detected offsite. A release summary incudes whatever other pertinent information is available for each release incident. This document includes effluent release information for 433 tests, some of which have simultaneous detonations. However, only 52 of these are designated as having offsite releases

  1. Radiological effluents released from US continental tests, 1961 through 1992. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Schoengold, C.R.; DeMarre, M.E.; Kirkwood, E.M.

    1996-08-01

    This report documents all continental tests from September 15, 1961, through September 23, 1992, from which radioactive effluents were released. The report includes both updated information previously published in the publicly available May, 1990 report, DOE/NV-317, ``Radiological Effluents Released from Announced US Continental Tests 1961 through 1988``, and effluent release information on formerly unannounced tests. General information provided for each test includes the date, time, location, type of test, sponsoring laboratory and/or agency or other sponsor, depth of burial, purpose, yield or yield range, extent of release (onsite only or offsite), and category of release (detonation-time versus post-test operations). Where a test with simultaneous detonations is listed, location, depth of burial and yield information are given for each detonation if applicable, as well as the specific source of the release. A summary of each release incident by type of release is included. For a detonation-time release, the effluent curies are expressed at R+12 hours. For a controlled releases from tunnel-tests, the effluent curies are expressed at both time of release and at R+12 hours. All other types are listed at the time of the release. In addition, a qualitative statement of the isotopes in the effluent is included for detonation-time and controlled releases and a quantitative listing is included for all other types. Offsite release information includes the cloud direction, the maximum activity detected in the air offsite, the maximum gamma exposure rate detected offsite, the maximum iodine level detected offsite, and the maximum distance radiation was detected offsite. A release summary incudes whatever other pertinent information is available for each release incident. This document includes effluent release information for 433 tests, some of which have simultaneous detonations. However, only 52 of these are designated as having offsite releases.

  2. Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells

    Science.gov (United States)

    Sakata, Ichiro; Park, Won-Mee; Walker, Angela K.; Piper, Paul K.; Chuang, Jen-Chieh; Osborne-Lawrence, Sherri

    2012-01-01

    The peptide hormone ghrelin is released from a distinct group of gastrointestinal cells in response to caloric restriction, whereas its levels fall after eating. The mechanisms by which ghrelin secretion is regulated remain largely unknown. Here, we have used primary cultures of mouse gastric mucosal cells to investigate ghrelin secretion, with an emphasis on the role of glucose. Ghrelin secretion from these cells upon exposure to different d-glucose concentrations, the glucose antimetabolite 2-deoxy-d-glucose, and other potential secretagogues was assessed. The expression profile of proteins involved in glucose transport, metabolism, and utilization within highly enriched pools of mouse ghrelin cells and within cultured ghrelinoma cells was also determined. Ghrelin release negatively correlated with d-glucose concentration. Insulin blocked ghrelin release, but only in a low d-glucose environment. 2-Deoxy-d-glucose prevented the inhibitory effect of high d-glucose exposure on ghrelin release. mRNAs encoding several facilitative glucose transporters, hexokinases, the ATP-sensitive potassium channel subunit Kir6.2, and sulfonylurea type 1 receptor were expressed highly within ghrelin cells, although neither tolbutamide nor diazoxide exerted direct effects on ghrelin secretion. These findings suggest that direct exposure of ghrelin cells to low ambient d-glucose stimulates ghrelin release, whereas high d-glucose and glucose metabolism within ghrelin cells block ghrelin release. Also, low d-glucose sensitizes ghrelin cells to insulin. Various glucose transporters, channels, and enzymes that mediate glucose responsiveness in other cell types may contribute to the ghrelin cell machinery involved in regulating ghrelin secretion under these different glucose environments, although their exact roles in ghrelin release remain uncertain. PMID:22414807

  3. Energy policies of the European Union

    International Nuclear Information System (INIS)

    Lyons, P.K.

    1994-09-01

    This report takes stock of what has been achieved and where the European Community is going in terms of energy policy and also looks at the full extent of the Union's energy sector competances. The chapters deal with the European Commission's programme to create an internal energy market through implementing new Directives and by means of an approach through competition. A further two chapters concentrate on environmental policy with respect to emissions control and the greenhouse effect. Two broad policy areas - Community Initiative and trans-European networks - are examined in a consideration of the connections between energy and economic and social cohesion. Security of supply is the fourth and traditional pillar of energy policy to be considered. Three policy areas which do not fit into these first four categories are dealt with in individual chapters. These are: nuclear issues, research and development, and a wider Europe. A concluding chapter suggests that there is an urgent need for a new way of dealing with energy in the European Union which has a myriad of policies affecting energy but no energy policy. The appendices include a document summary for each of the main chapters and a glossary. (UK)

  4. International perceptions of US nuclear policy.

    Energy Technology Data Exchange (ETDEWEB)

    Stanley, Elizabeth A. (Georgetown Universtiy, Washington, DC)

    2006-02-01

    The report presents a summary of international perceptions and beliefs about US nuclear policy, focusing on four countries--China, Iran, Pakistan and Germany--chosen because they span the spectrum of states with which the United States has relationships. A paradox is pointed out: that although the goal of US nuclear policy is to make the United States and its allies safer through a policy of deterrence, international perceptions of US nuclear policy may actually be making the US less safe by eroding its soft power and global leadership position. Broadly held perceptions include a pattern of US hypocrisy and double standards--one set for the US and its allies, and another set for all others. Importantly, the US nuclear posture is not seen in a vacuum, but as one piece of the United States behavior on the world stage. Because of this, the potential direct side effects of any negative international perceptions of US nuclear policy can be somewhat mitigated, dependent on other US policies and actions. The more indirect and long term relation of US nuclear policy to US international reputation and soft power, however, matters immensely to successful multilateral and proactive engagement on other pressing global issues.

  5. International perceptions of US nuclear policy

    International Nuclear Information System (INIS)

    Stanley, Elizabeth A.

    2006-01-01

    The report presents a summary of international perceptions and beliefs about US nuclear policy, focusing on four countries--China, Iran, Pakistan and Germany--chosen because they span the spectrum of states with which the United States has relationships. A paradox is pointed out: that although the goal of US nuclear policy is to make the United States and its allies safer through a policy of deterrence, international perceptions of US nuclear policy may actually be making the US less safe by eroding its soft power and global leadership position. Broadly held perceptions include a pattern of US hypocrisy and double standards--one set for the US and its allies, and another set for all others. Importantly, the US nuclear posture is not seen in a vacuum, but as one piece of the United States behavior on the world stage. Because of this, the potential direct side effects of any negative international perceptions of US nuclear policy can be somewhat mitigated, dependent on other US policies and actions. The more indirect and long term relation of US nuclear policy to US international reputation and soft power, however, matters immensely to successful multilateral and proactive engagement on other pressing global issues

  6. Nursing work directions in Australia: does evidence drive the policy?

    Science.gov (United States)

    Roche, Michael; Duffield, Christine; Aisbett, Chris; Diers, Donna; Stasa, Helen

    2012-01-01

    A significant body of research has shown a relationship between nurse staffing (in particular, skill-mix: the proportion of Registered Nurses [RNs]) and both morbidity and mortality. This relationship is typically investigated by measuring the incidence of Nursing Sensitive Outcomes (NSOs) under different skill-mix levels. Yet whilst the evidence suggests that richer skill-mix is associated with a lower incidence of NSOs, recent Australian policy reforms have proposed the replacement of Registered Nurses with less qualified staff. The present study sought to examine the relationship between staffing, skill-mix, and incidence of NSOs at two hospitals in one Australian state. The study sought to determine the rate of occurrence of several NSOs, the relationship of skill-mix to that rate, and the number of patients affected per annum. It was found that the current rate of NSOs across wards ranged from 0.17% to 1.05%, and that there was an inverse relationship between the proportion of hours worked by RNs and NSO rates: an increase of 10% in the proportion of hours worked by RNs was linked to a decrease in NSO rates by between 11% and 45%. It was estimated that increasing the RN staffing percentage by 10% would mean 160 fewer adverse outcomes for patients per year across these two hospitals. Importantly, increases in nursing hours overall (without increases in skill-mix) had no significant effect on patient outcomes. These findings challenge current policy recommendations, which propose increasing the number of unregistered staff without increasing skill-mix.

  7. Direct contamination - seasonality

    International Nuclear Information System (INIS)

    Aarkrog, A.

    1994-01-01

    Direct contamination is the primary pathway to terrestrial vegetation in the first period after an activity release to the atmosphere. All radionuclides are able to be transferred via this pathway. Deposition, interception and retention are the three processes involved in direct contamination of crops. Wet deposition is more important than dry deposition in temperature regions. Resuspension and rainsplash both belong to secondary direct deposition and became evident for e.g. radiocaesium after the Chernobyl accident. Seasonality is the varying response to radioactive contamination of crops according to the time of the year when the contamination occurs. Shortlived radionuclides (as 131 I) and those that mainly enter the foodchain by direct contamination (e.g. 137 Cs) are especially important in this connection. In particular, the contamination of cereal crops is influenced by seasonality. As a result of seasonality the impact of the Chernobyl accident on the radioactive contamination of human diet was for the same deposition density higher in southern than in northern Europe. (orig.)

  8. Environmental policy in the 9th German Bundestag and the Bundesrat (1980-1983)

    International Nuclear Information System (INIS)

    1983-01-01

    This presentation of environmental policy constitutes the continuation of copies No. 49 and No. 72 of the 'Materialien' [Materials] (Environmental policy in the 7th German Bundestag or environmental policy in the 8. German Bundestag and in the Bundesrat, resp. - 1976 to 1980). References to factual terms espec. indications of speech references, apply to the register annexed to 'Verhandlungen des Deutschen Bundestages und des Bundesrates' (Deliberations of the German Bundestag and the Bundesrat) for the 9th period of office on which the 'Materialie' is based. Among other things, the 'Materialie' comprises: General fundamentals and primaples, aspects of structural policy, scientific and technical/technological fundamentals, organizational fundamentals, international and intergovernmental co-operation, air-borne emission abatement, waste management, chemical substances released to environment, nuclear energy. (orig./HP) [de

  9. Red light for Green Paper: The EU policy on energy efficiency

    International Nuclear Information System (INIS)

    Nilsson, Mats

    2007-01-01

    The EU Green Paper on energy efficiency calls for action to decrease energy use and thus achieve increased competitiveness, fulfil the environmental targets and increase security of supply. In this comment, we examine the role the EU Commission suggest that energy efficiency, and policies supporting energy efficiency, takes. The policies and the suggestions are qualitatively elaborated upon in the light of the goal of a common European electricity market. We suggest that the rationales for the energy efficiency measures are weak, and that the suggested goals of increased competitiveness, environmental targets, and security of supply are best reached with the direct measures especially designed for each goal. Some of the energy efficiency measures may counter-act other direct policies. Further, The Green Paper measures may prove detrimental to the European Electricity market insofar as the policies suggested could lead to a policy fatigue among the electricity consumers

  10. Reagan outlines nonproliferation policy

    International Nuclear Information System (INIS)

    Walsh, J.

    1981-01-01

    The Reagan Administration wants to shift from efforts to impose direct control over the fuel cycle and nuclear technology to a framework based on cooperation and initiatives for greater political stability. A nuclear-free zone for the Middle East is one area to explore. Congress responded to this announced plan with a counter move to tighten non-proliferation strategies. Reagan's policy will be to restore the US as an aggressive, but reliable nuclear trading partner operating under adequate safeguards. Critics find this approach dangerous and contradictory. The policy is still too general to answer specific questions about bilateral arrangements, generic permits, plutonium recycling, and other matters

  11. The NPC: A Higher Priority for Networking Policy

    Science.gov (United States)

    Kuhns, Jeff C.

    2006-01-01

    This article discusses the scope of activities of the Network Policy Council (NPC), which has been designed to provide a more direct channel of communications within EDUCAUSE and to provide policy formulation more visibility. The NPC is an advisory council to EDUCAUSE whose members are selected from those who have interest in this area and are…

  12. Compliance. Regulatory policy P-211

    International Nuclear Information System (INIS)

    2001-05-01

    This regulatory policy describes the basic principles and directives for establishing and conducting the Canadian Nuclear Safety Commission (CNSC) Compliance Program. The program is aimed at securing compliance by regulated persons with regulatory requirements made under the Nuclear Safety and Control Act ('the Act'). The policy applies to persons who are regulated by the CNSC through the Act, regulations and licences, as well as by decisions and orders made under the Act. The policy applies to officers and employees of the CNSC, and its authorized representatives or agents, who are involved in developing and carrying out compliance activities. Compliance, in the context of this policy, means conformity by regulated persons with the legally binding requirements of the Act, and the CNSC regulations, licences, decisions, and orders made under the Act. Compliance activities are CNSC measures of promotion, verification and enforcement aimed at securing compliance by regulated person with the applicable legally binding requirements. (author)

  13. 32 CFR 286h.3 - Policy.

    Science.gov (United States)

    2010-07-01

    ... cost or pricing data, profit data, overhead and direct labor rates, and manufacturing processes and... requests for information contained in the National Military Strategy Document (including annexes) and the... cost estimates) or would adversely impact the government negotiating strategy shall not be released. (7...

  14. A new technique of single portal endoscopic carpal tunnel release.

    Science.gov (United States)

    Ip, Wing-Yuk Josephine; Sweed, Tamer Ahmed; Fung, Kwok Keung Boris; Tipoe, George L; Pun, Tze Shing

    2012-03-01

    Since the first description of endoscopic carpal tunnel release (ECTR) in 1987 by Okutsu many endoscopic techniques have been developed, but the majority of the literature on ECTR has dealt with the Chow and Agee techniques. ECTR is indicated for carpal tunnel syndrome that is not responding to conservative treatment for 6 months. This new technique of ECTR is a single-portal technique using instruments originally designed for endoscopic cubital tunnel release, with no disposable instruments used. It also has the advantage of performing the release with the median nerve protected under direct vision. Ten cases were operated with this technique after performing the procedure on 8 hands of 4 fresh frozen cadavers. There were no neurovascular or tendon injuries with this technique and patients were satisfied with the results.

  15. Mode of foreign entry, technology transfer, and foreign direct investment policy

    OpenAIRE

    Mattoo, Aaditya; Olarreaga, Marcelo; Saggi, Kamal

    2001-01-01

    Foreign direct investment can take place through the direct entry of foreign firms or the acquisition of existing domestic firms. Mattoo, Olarreaga, and Saggi examine the preferences of a foreign firm and the host country government with respect to these two modes of foreign direct investment in the presence of costly technology transfer. The tradeoff between technology transfer and market...

  16. Direct projection from the suprachiasmatic nucleus to hypophysiotrophic corticotropin-releasing factor immunoreactive cells in the paraventricular nucleus of the hypothalamus demonstrated...

    DEFF Research Database (Denmark)

    Vrang, N.; Larsen, P.J.; Mikkelsen, J.D.

    1995-01-01

    Suprachiasmatic nucleus, paraventricular nucleus, circadian rhythms, phaseolus vulgaris-leucoagglutinin, corticotropin-releasing factor, dual immunocytochemistry......Suprachiasmatic nucleus, paraventricular nucleus, circadian rhythms, phaseolus vulgaris-leucoagglutinin, corticotropin-releasing factor, dual immunocytochemistry...

  17. The policy relevance of global environmental change research

    International Nuclear Information System (INIS)

    Yarnal, Brent

    1996-01-01

    Many scientists are striving to identify and promote the policy implications of their global change research. Much basic research on global environmental change cannot advance policy directly, but new projects can determine the relevance of their research to decision makers and build policy-relevant products into the work. Similarly, many ongoing projects can alter or add to the present science design to make the research policy relevant. Thus, this paper shows scientists working on global change how to make their research policy relevant. It demonstrates how research on physical global change relates to human dimensions studies and integrated assessments. It also presents an example of how policy relevance can be fit retroactively into a global change project (in this case, SRBEX-the Susquehanna River Basin Experiment) and how that addition can enhance the project's status and science. The paper concludes that policy relevance is desirable from social and scientific perspectives

  18. Excessive nickel release from mobile phones--a persistent cause of nickel allergy and dermatitis

    DEFF Research Database (Denmark)

    Jensen, Peter; Johansen, Jeanne D; Zachariae, Claus

    2011-01-01

    Despite the political intention to limit nickel allergy and dermatitis in Europeans, nickel allergy remains frequent. There are several explanations for the persistence of nickel allergy and dermatitis, including the increasing use of mobile phones. Before regulation of nickel release from mobile...... phones, we showed that eight (19.5%) of 41 mobile phones marketed in Denmark between 2003 and 2007 released nickel in concentrations that may result in nickel allergy and dermatitis. In 2009, the EU Nickel Directive was revised to include nickel-releasing mobile phones....

  19. Excessive nickel release from mobile phones--a persistent cause of nickel allergy and dermatitis

    DEFF Research Database (Denmark)

    Jensen, Peter; Johansen, Jeanne D; Zachariae, Claus

    2011-01-01

    phones, we showed that eight (19.5%) of 41 mobile phones marketed in Denmark between 2003 and 2007 released nickel in concentrations that may result in nickel allergy and dermatitis. In 2009, the EU Nickel Directive was revised to include nickel-releasing mobile phones.......Despite the political intention to limit nickel allergy and dermatitis in Europeans, nickel allergy remains frequent. There are several explanations for the persistence of nickel allergy and dermatitis, including the increasing use of mobile phones. Before regulation of nickel release from mobile...

  20. Regional impacts of abolishing direct payments

    DEFF Research Database (Denmark)

    Uthes, Sandra; Priorr, Annette; Zander, Peter

    2011-01-01

    The direct payment system of the Common Agricultural Policy (CAP) provides income transfers to European farmers. Recently, several countries including England and Sweden have advocated the elimination of direct payments after 2013. The extent to which an elimination of direct payments would affect...... with different production orientations and land management types was modeled under the presence and absence of direct payments using a combination of agent-based and bio-economic modeling. We found that the initial characteristics of the regions, such as the historical farm structure and regional site conditions...

  1. ROLE OF STATE PROTECTIONISM IN DEPRECIATION POLICY FORMATION

    Directory of Open Access Journals (Sweden)

    Darya Trachova

    2017-12-01

    Full Text Available The purpose of the paper is a generalization of state protectionism measures concerning the depreciation policy formation, which has resulted in economic growth in countries with a stable economy and their adaptation to economic conditions of Ukraine. Methodology. For writing the paper, the grouping and comparison methods were used for the research of business peculiarities of foreign and national enterprises’ operation and their impact on the enterprise depreciation policy formation; abstract-logic one was used during the examination of peculiarities of depreciation policy formation abroad; analysis and synthesis were used for the investigation of impact factors of different state regulation measures on efficiency of assets’ renewal and enterprise depreciation fund use, as well as stimulation of investments in the science and technology progress. Results. State depreciation policy is the basis in investment and innovation process, as well as one of the most important mechanisms for promoting the self-financing policy. In the developed countries, the state policy concerning the accelerated depreciation has become the main tool for economic growth. Depreciation policy reforming has to be conducted within and out of an enterprise simultaneously. Under existing conditions, the enterprise’s depreciation fund formation is impossible at the expense of its own resources. The changes of regulatory support for enterprise activity are necessary for depreciation fund forming. Tax protectionism has to be carried out in two directions: at the expense of profit redistribution before taxation as the special-purpose funding of fixed assets’ renewal as far as enterprise profitability allows and under the condition of the document approved the renewal of manufacturing capacities after the end of operation period. The control over state protectionism implementation regarding the tax heaven and directing funds for innovative renewal of fixed assets has to

  2. Political motives in climate and energy policy

    Energy Technology Data Exchange (ETDEWEB)

    Bruvoll, Annegrete; Dalen, Hanne Marit; Larsen, Bodil M.

    2012-07-01

    Standard economic theory provides clear guidance on the design of cost-efficient policy in the presence of imperfect markets and externalities. However, observed policies reveal extensive discrepancies between principles and practise. Based on interviews with core politicians from the Norwegian parliament, we investigate causes for the lack of cost efficiency in climate and energy policy. We find that politicians agree with the notion of cost efficiency in principle, but rather than ascribing efficient instruments directed at specific policy goals, they include concerns for industrial and regional development, income distribution and employment in the environmental policy design. Lacking insight in the functioning of economic instruments and perceptions of a non-binding budget constraint also violate the requirements for efficient policy decisions. The findings point to the role of economists and social scientists to communicate the functioning of complex instruments. Improved compensation procedures could help reduce the politicians' incentives to undermine efficiency in order to avoid unwanted distributional effects.(Author)

  3. Accelerated in-vitro release testing methods for extended-release parenteral dosage forms.

    Science.gov (United States)

    Shen, Jie; Burgess, Diane J

    2012-07-01

    This review highlights current methods and strategies for accelerated in-vitro drug release testing of extended-release parenteral dosage forms such as polymeric microparticulate systems, lipid microparticulate systems, in-situ depot-forming systems and implants. Extended-release parenteral dosage forms are typically designed to maintain the effective drug concentration over periods of weeks, months or even years. Consequently, 'real-time' in-vitro release tests for these dosage forms are often run over a long time period. Accelerated in-vitro release methods can provide rapid evaluation and therefore are desirable for quality control purposes. To this end, different accelerated in-vitro release methods using United States Pharmacopeia (USP) apparatus have been developed. Different mechanisms of accelerating drug release from extended-release parenteral dosage forms, along with the accelerated in-vitro release testing methods currently employed are discussed. Accelerated in-vitro release testing methods with good discriminatory ability are critical for quality control of extended-release parenteral products. Methods that can be used in the development of in-vitro-in-vivo correlation (IVIVC) are desirable; however, for complex parenteral products this may not always be achievable. © 2012 The Authors. JPP © 2012 Royal Pharmaceutical Society.

  4. Accelerated in vitro release testing methods for extended release parenteral dosage forms

    Science.gov (United States)

    Shen, Jie; Burgess, Diane J.

    2012-01-01

    Objectives This review highlights current methods and strategies for accelerated in vitro drug release testing of extended release parenteral dosage forms such as polymeric microparticulate systems, lipid microparticulate systems, in situ depot-forming systems, and implants. Key findings Extended release parenteral dosage forms are typically designed to maintain the effective drug concentration over periods of weeks, months or even years. Consequently, “real-time” in vitro release tests for these dosage forms are often run over a long time period. Accelerated in vitro release methods can provide rapid evaluation and therefore are desirable for quality control purposes. To this end, different accelerated in vitro release methods using United States Pharmacopoeia (USP) apparatus have been developed. Different mechanisms of accelerating drug release from extended release parenteral dosage forms, along with the accelerated in vitro release testing methods currently employed are discussed. Conclusions Accelerated in vitro release testing methods with good discriminatory ability are critical for quality control of extended release parenteral products. Methods that can be used in the development of in vitro-in vivo correlation (IVIVC) are desirable, however for complex parenteral products this may not always be achievable. PMID:22686344

  5. Renewable resource policy when distributional impacts matter

    International Nuclear Information System (INIS)

    Horan, R.D.; Shortle, J.S.; Bulte, E.H.

    1999-01-01

    The standard assumption in bioeconomic resource models is that optimal policies maximize the present value of economic surplus to society. This assumption implies that regulatory agencies should not be concerned with the distributional consequences of management strategies. Both contemporary welfare-theoretic and rent-seeking approaches suggests distributional issues are important in designing resource management policies. This paper explores resource management when the managing agency has preferences defined over the economic welfare of various groups with a direct economic interest in the use of resources. Policy schemes consistent with this approach are derived and compared with standard results. 42 refs

  6. Nuclear power hazard control policy

    Energy Technology Data Exchange (ETDEWEB)

    Chicken, J C

    1982-01-01

    This study presents an analysis of the factors that appear to have influenced the formation and form of nuclear power hazard control policy in Britain. A simple account is given of the technical nature of nuclear hazards and of the legal and administrative framework that has been constructed to control them. The subsequent analysis concentrates primarily on the influence exerted by social and political factors. Particular attention is directed to those political groups which have developed a special interest in the problems of nuclear power, and to the interplay between organised groupings and public opinion generally. The metamorphosis of these groupings is traced from the origins of the nuclear industry in the Second World War to their prominent role during the Windscale Inquiry. Attention is given to the policy constraint imposed by increased expectations in the form of demands for higher standards of living, and improvements in the quality of the environment. The study is concerned with both policy-making and with policy implementation; with interest articulation as well as with the functioning of formal institutions. The evolution of policy takes place in an atmosphere of keen economic debate and conflicting moral perceptions. A model of the policy-making system is postulated.

  7. Nuclear power hazard control policy

    International Nuclear Information System (INIS)

    Chicken, J.C.

    1982-01-01

    This study presents an analysis of the factors that appear to have influenced the formation and form of nuclear power hazard control policy in Britain. A simple account is given of the technical nature of nuclear hazards and of the legal and administrative framework that has been constructed to control them. The subsequent analysis concentrates primarily on the influence exerted by social and political factors. Particular attention is directed to those political groups which have developed a special interest in the problems of nuclear power, and to the interplay between organised groupings and public opinion generally. The metamorphosis of these groupings is traced from the origins of the nuclear industry in the Second World War to their prominent role during the Windscale Inquiry. Attention is given to the policy constraint imposed by increased expectations in the form of demands for higher standards of living, and improvements in the quality of the environment. The study is concerned with both policy-making and with policy implementation; with interest articulation as well as with the functioning of formal institutions. The evolution of policy takes place in an atmosphere of keen economic debate and conflicting moral perceptions. A model of the policy-making system is postulated. (author)

  8. FEDERAL AND REGIONAL CLUSTER POLICY OF THE RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    Markov L. S.

    2017-12-01

    Full Text Available The article reviews the history of cluster policy in Russia at the federal and regional levels. The federal cluster policy is realized in three directions, studying which allowed us to outline the main features of a formalized cluster that claims state support. The trend of reorientation of the cluster policy from supporting clusters and their infrastructure to cluster projects is revealed. Systematization and comparative analysis of the cluster policy in the regions of the country leading in terms of cluster development is carried out. It is established that the regional cluster policy is at a nascent stage and is a projection of the federal programs. At the regional level, there is no institutional basis for the cluster policy in Russia. The regional cluster policy is characterized by homogeneity of organizational structures.

  9. Russia's Energy Policies and Ukraine's NATO Candidacy

    National Research Council Canada - National Science Library

    Imblum, Mark A

    2008-01-01

    .... The emerging interaction between Alliance enlargement and energy policies may yet affect Ukraine's future relationship with NATO as well as Russia and even determine which direction NATO takes...

  10. The evolution of Malaysia’s immigration policy since 1970

    OpenAIRE

    Avila, Michelle B.

    2015-01-01

    Approved for public release; distribution is unlimited In the 1970s, Malaysia’s government promoted economic growth through an economic structural change from agriculture to industry. During the economic changeover, Malaysia’s lack of human capital contributed to the persistent labor shortages. To meet the demand for labor, especially in manufacturing and construction, the government adopted a liberal immigration policy that permitted large numbers of workers to enter the country. Although...

  11. Profile of Fluoride Release from a Nanohybrid Composite Resin

    Directory of Open Access Journals (Sweden)

    Raquel Assed Bezerra Silva

    2015-02-01

    Full Text Available The aim of this study was to evaluate in vitro the amount and profile of fluoride release from a fluoride-containing nanohybrid composite resin (Tetric® N-Ceram by direct potentiometry. Thirty specimens (5 mm diameter x 3 mm high; n=10/material were made of Tetric® N-Ceram, Vitremer® resin-modified glass ionomer cement (RMGIC (positive control or Filtek® Z350 nanofill composite resin (negative control. The specimens were stored individually in plastic tubes containing 1 mL of artificial saliva at 37°C, which was daily renewed during 15 days. At each renewal of saliva, the amount of fluoride ions released in the solution was measured using a fluoride ion-selective electrode with ion analyzer, and the values obtained in mV were converted to ppm (µg/mL. Data were analyzed statistically by ANOVA and Tukey’s post-hoc test at a significance level of 5%. The results showed that the resins Tetric® N-Ceram and Filtek® Z350 did not release significant amounts of fluoride during the whole period of evaluation (p>0.05. Only Vitremer® released significant amounts of fluoride ions during the 15 days of the experiment, with greater release in first 2 days (p0.05. In conclusion, the nanohybrid composite resin Tetric® N-Ceram did not present in vitro fluoride-releasing capacity throughout the 15 days of study.

  12. Effects of tetracaine on insulin release and calcium handling by rat pancreatic islets

    International Nuclear Information System (INIS)

    Abdel El Motal, S.M.A.; Pian-Smith, M.C.M.; Sharp, G.W.G.

    1987-01-01

    The effects of tetracaine on insulin release and 45 Ca 2+ handling by rat pancreatic islets have been studied under basal, glucose-stimulated, and 3-isobutyl-1-methylxanthine (IBMX)-stimulated conditions. Islets were isolated by the use of collagenase and used either directly (freshly isolated islets) or after a period under tissue culture conditions. Tetracaine was found to stimulate insulin release under basal conditions, to inhibit glucose-stimulated insulin release, and to potentiate insulin release stimulated by IBMX. In studies on the mechanisms underlying these effects, tetracaine was found to decrease glucose-stimulated net retention of 45 Ca 2+ (by an action to block the voltage-dependent Ca channels) and to mobilize Ca 2+ from intracellular stores. These two actions form the basis for the inhibition of glucose-stimulated insulin release, which depends heavily on Ca 2+ entry via the voltage-dependent channels and the synergism with IBMX to potentiate release. No inhibition of IBMX-stimulated release occurs because IBMX does not use the voltage-dependent channels to raise intracellular Ca 2+

  13. Health as foreign policy: harnessing globalization for health.

    Science.gov (United States)

    Fidler, David P

    2006-12-01

    This paper explores the importance for health promotion of the rise of public health as a foreign policy issue. Although health promotion encompassed foreign policy as part of 'healthy public policy', mainstream foreign policy neglected public health and health promotion's role in it. Globalization forces health promotion, however, to address directly the relationship between public health and foreign policy. The need for 'health as foreign policy' is apparent from the prominence public health now has in all the basic governance functions served by foreign policy. The Secretary-General's United Nations (UN) reform proposals demonstrate the importance of foreign policy to health promotion as a core component of public health because the proposals embed public health in each element of the Secretary-General's vision for the UN in the 21st century. The emergence of health as foreign policy presents opportunities and risks for health promotion that can be managed by emphasizing that public health constitutes an integrated public good that benefits all governance tasks served by foreign policy. Any effort to harness globalization for public health will have to make health as foreign policy a centerpiece of its ambitions, and this task is now health promotion's burden and opportunity.

  14. Active social policies in the EU

    DEFF Research Database (Denmark)

    Berkel, Rik van; Møller, Iver Hornemann

    of work in modern societies and the implications this has or should have for scientific and sociopolitical thinking about inclusion, participation and activation; the "paradigm shift" that can be observed in present social policies, which increasingly become directed at participation rather than (income...... and training/education schemes; and the implications of these research findings for the issues outlined above, that is our thinking of work in relation to participation on the one hand, and social policies aiming at increasing participation on the other....

  15. Controlled release of insect sex pheromones from paraffin wax and emulsions.

    Science.gov (United States)

    Atterholt, C A; Delwiche, M J; Rice, R E; Krochta, J M

    1999-02-22

    Paraffin wax and aqueous paraffin emulsions can be used as controlled release carriers for insect sex pheromones for mating disruption of orchard pests. Paraffin can be applied at ambient temperature as an aqueous emulsion, adheres to tree bark or foliage, releases pheromone for an extended period of time, and will slowly erode from bark and biodegrade in soil. Pheromone emulsions can be applied with simple spray equipment. Pheromone release-rates from paraffin were measured in laboratory flow-cell experiments. Pheromone was trapped from an air stream with an adsorbent, eluted periodically, and quantified by gas chromatography. Pheromone release from paraffin was partition-controlled, providing a constant (zero-order) release rate. A typical paraffin emulsion consisted of 30% paraffin, 4% pheromone, 4% soy oil, 1% vitamin E, 2% emulsifier, and the balance water. Soy oil and vitamin E acted as volatility suppressants. A constant release of oriental fruit moth pheromone from paraffin emulsions was observed in the laboratory for more than 100 days at 27 degreesC, with release-rates ranging from 0.4 to 2 mg/day, depending on the concentration and surface area of the dried emulsion. The use of paraffin emulsions is a viable method for direct application of insect pheromones for mating disruption. Sprayable formulations can be designed to release insect pheromones to the environment at a rate necessary for insect control by mating disruption. At temperatures below 38 degreesC, zero-order release was observed. At 38 degreesC and higher, pheromone oxidation occurred. A partition-controlled release mechanism was supported by a zero-order pheromone release-rate, low air/wax partition coefficients, and pheromone solubility in paraffin.

  16. Outside-out "sniffer-patch" clamp technique for in situ measures of neurotransmitter release.

    Science.gov (United States)

    Muller-Chrétien, Emilie

    2014-01-01

    The mechanism underlying neurotransmitter release is a critical research domain for the understanding of neuronal network function; however, few techniques are available for the direct detection and measurement of neurotransmitter release. To date, the sniffer-patch clamp technique is mainly used to investigate these mechanisms from individual cultured cells. In this study, we propose to adapt the sniffer-patch clamp technique to in situ detection of neurosecretion. Using outside-out patches from donor cells as specific biosensors plunged in acute cerebral slices, this technique allows for proper detection and quantification of neurotransmitter release at the level of the neuronal network.

  17. Proinflammatory mediators stimulate neutrophil-directed angiogenesis.

    LENUS (Irish Health Repository)

    McCourt, M

    2012-02-03

    BACKGROUND: Vascular endothelial growth factor (VEGF; vascular permeability factor) is one of the most potent proangiogenic cytokines, and it plays a central role in mediating the process of angiogenesis or new blood vessel formation. Neutrophils (PMNs) recently have been shown to produce VEGF. HYPOTHESIS: The acute inflammatory response is a potent stimulus for PMN-directed angiogenesis. METHODS: Neutrophils were isolated from healthy volunteers and stimulated with lipopolysaccharide (LPS), tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), and anti-human Fas monoclonal antibody. Culture supernatants were assayed for VEGF using enzyme-linked immunosorbent assays. Culture supernatants from LPS- and TNF-alpha-stimulated PMNs were then added to human umbilical vein endothelial cells and human microvessel endothelial cells and assessed for endothelial cell proliferation using 5-bromodeoxyuridine labeling. Tubule formation was also assessed on MATRIGEL basement membrane matrix. Neutrophils were lysed to measure total VEGF release, and VEGF expression was detected using Western blot analysis. RESULTS: Lipopolysaccharide and TNF-alpha stimulation resulted in significantly increased release of PMN VEGF (532+\\/-49 and 484+\\/-80 pg\\/mL, respectively; for all, presented as mean +\\/- SEM) compared with control experiments (32+\\/-4 pg\\/mL). Interleukin 6 and Fas had no effect. Culture supernatants from LPS- and TNF-alpha-stimulated PMNs also resulted in significant increases (P<.005) in macrovascular and microvascular endothelial cell proliferation and tubule formation. Adding anti-human VEGF-neutralizing polyclonal antibody to stimulated PMN supernatant inhibited these effects. Total VEGF release following cell lysis and Western blot analysis suggests that the VEGF is released from an intracellular store. CONCLUSION: Activated human PMNs are directly angiogenic by releasing VEGF, and this has important implications for inflammation, capillary leak syndrome

  18. Breast screening policy: Are we heading in the right direction?

    International Nuclear Information System (INIS)

    Evans, A.; Whelehan, P.

    2011-01-01

    There is a large body of evidence supporting 2-yearly screening of women aged 50-69 years. There is good evidence for a mortality reduction from mammographic screening in women aged 40 to 49 years but a 1-year interval is required. The lack of specificity of screening in young women does remain a problem. There is no evidence to suggest that a single screen between the ages of 47 and 50 years within a programme screening at 3-year intervals will reduce mortality; the trials showing a mortality benefit in women in their 40s included multiple screening episodes and shorter screening intervals. There is no randomized, controlled trial evidence to support screening in women aged above 70 years and screening this age group will cause greater harm than in younger women through higher rates of over-diagnosis and consequent over-treatment. The randomized phase of the screening age extension, which at the moment is planned to last only 6 years, should not be immediately followed by general implementation of the policy. Only if and when additional mortality reductions and an acceptable balance between benefit and harms are shown to be achieved by the extra screens should the 2007 Cancer Reform Strategy policy on age extension be implemented. Resources saved by delaying or abandoning the roll-out of the age extension could potentially be redirected towards reducing the current 3 year screening interval to 2 years in women aged 50-69 years. However, reducing the screening interval to 2 years for women aged 50-69 years would require significantly more screening invitations and resources than the proposed age extension.

  19. Breast screening policy: Are we heading in the right direction?

    Energy Technology Data Exchange (ETDEWEB)

    Evans, A., E-mail: a.z.evans@dundee.ac.uk [Dundee Cancer Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee (United Kingdom); Whelehan, P. [Dundee Cancer Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee (United Kingdom)

    2011-10-15

    There is a large body of evidence supporting 2-yearly screening of women aged 50-69 years. There is good evidence for a mortality reduction from mammographic screening in women aged 40 to 49 years but a 1-year interval is required. The lack of specificity of screening in young women does remain a problem. There is no evidence to suggest that a single screen between the ages of 47 and 50 years within a programme screening at 3-year intervals will reduce mortality; the trials showing a mortality benefit in women in their 40s included multiple screening episodes and shorter screening intervals. There is no randomized, controlled trial evidence to support screening in women aged above 70 years and screening this age group will cause greater harm than in younger women through higher rates of over-diagnosis and consequent over-treatment. The randomized phase of the screening age extension, which at the moment is planned to last only 6 years, should not be immediately followed by general implementation of the policy. Only if and when additional mortality reductions and an acceptable balance between benefit and harms are shown to be achieved by the extra screens should the 2007 Cancer Reform Strategy policy on age extension be implemented. Resources saved by delaying or abandoning the roll-out of the age extension could potentially be redirected towards reducing the current 3 year screening interval to 2 years in women aged 50-69 years. However, reducing the screening interval to 2 years for women aged 50-69 years would require significantly more screening invitations and resources than the proposed age extension.

  20. Regulation of gonadotropin-releasing hormone neurons by glucose

    Science.gov (United States)

    Roland, Alison V.; Moenter, Suzanne M.

    2011-01-01

    Reproduction is influenced by energy balance, but the physiological pathways mediating their relationship have not been fully elucidated. As the central regulators of fertility, gonadotropin-releasing hormone (GnRH) neurons integrate numerous physiological signals, including metabolic cues. Circulating glucose levels regulate GnRH release and may in part mediate the effects of negative energy balance on fertility. Existing evidence suggests that neural pathways originating in the hindbrain, as well as in the hypothalamic feeding nuclei, transmit information concerning glucose availability to GnRH neurons. Here we review recent evidence suggesting that GnRH neurons may directly sense changes in glucose availability by a mechanism involving adenosine monophosphate-activated protein kinase (AMPK). These findings expand our understanding of how metabolic signaling in the brain regulates reproduction. PMID:21855365

  1. Therapeutic effects of 5-fluorouracil sustained-release particles in 81 malignant pericardial effusion patients

    Directory of Open Access Journals (Sweden)

    Yong-Li Ji

    2015-02-01

    Full Text Available This study aimed to investigate the clinical application value of the 5-fluorouracil (5-FU sustained-release particles implanted along the cardiac tangent direction into malignant pericardial effusion (MPCE. A total of 81 MPCE patients underwent pericardiocentesis, and were implanted with 5-FU sustained-release particles into the pericardial cavity under ultrasound guidance. The puncturing path was along the cardiac tangent direction. Ultrasound examinations were performed every week, and the efficacy was evaluated 4 weeks after treatment. The 45 patients who were treated with pericardial catheter drainage and simultaneous intracavitary chemotherapy were used as the control group. The success rate of pericardiocentesis was 100%. Ultrasound reviews performed 4 weeks after treatment showed that 71 cases achieved complete remission and eight cases achieved partial remission, while treatment was completely ineffective in two cases. The total remission rate was 97.53%, which was significantly higher than that of the control group (77.78%, p < 0.01. The implantation of 5-FU sustained-release particles along the cardiac tangent direction was safe, and demonstrated good efficacy and fewer adverse reactions. Thus, this method could be ideal for the treatment of MPCE.

  2. New mitotic regulators released from chromatin

    Directory of Open Access Journals (Sweden)

    Hideki eYokoyama

    2013-12-01

    Full Text Available Faithful action of the mitotic spindle segregates duplicated chromosomes into daughter cells. Perturbations of this process result in chromosome mis-segregation, leading to chromosomal instability and cancer development. Chromosomes are not simply passengers segregated by spindle microtubules but rather play a major active role in spindle assembly. The GTP bound form of the Ran GTPase (RanGTP, produced around chromosomes, locally activates spindle assembly factors. Recent studies have uncovered that chromosomes organize mitosis beyond spindle formation. They distinctly regulate other mitotic events, such as spindle maintenance in anaphase, which is essential for chromosome segregation. Furthermore, the direct function of chromosomes is not only to produce RanGTP but, in addition, to release key mitotic regulators from chromatin. Chromatin-remodeling factors and nuclear pore complex proteins, which have established functions on chromatin in interphase, dissociate from mitotic chromatin and function in spindle assembly or maintenance. Thus, chromosomes actively organize their own segregation using chromatin-releasing mitotic regulators as well as RanGTP.

  3. Radioimmunological and clinical studies with luteinizing hormone releasing hormone (LRH)

    International Nuclear Information System (INIS)

    Dahlen, H.G.

    1986-01-01

    Radioimmunoassay for Luteinizing Hormone Releasing Hormone (LRH) has been established, tested and applied. Optimal conditions for the performance with regards to incubation time, incubation temperature, concentration of antiserum and radiolabelled LRH have been established. The specificity of the LRH immunoassay was investigated. Problems with direct measurement of LRH in plasmas of radioimmunoassay are encountered. The LRH distribution in various tissues of the rat are investigated. By means of a system for continuous monitoring of LH and FSH in women the lowest effective dose of LRH causing a significant release of LH and FSH could be established. (Auth.)

  4. Exploring Alcohol Policy Approaches to Prevent Sexual Violence Perpetration

    Science.gov (United States)

    Lippy, Caroline; DeGue, Sarah

    2018-01-01

    Sexual violence continues to be a significant public health problem worldwide with serious consequences for individuals and communities. The implementation of prevention strategies that address risk and protective factors for sexual violence at the community level are important components of a comprehensive approach, but few such strategies have been identified or evaluated. The current review explores one potential opportunity for preventing sexual violence perpetration at the community level: alcohol policy. Alcohol policy has the potential to impact sexual violence perpetration through the direct effects of excessive alcohol consumption on behavior or through the impact of alcohol and alcohol outlets on social organization within communities. Policies affecting alcohol pricing, sale time, outlet density, drinking environment, marketing, and college environment are reviewed to identify existing evidence of impact on rates of sexual violence or related outcomes, including risk factors and related health behaviors. Several policy areas with initial evidence of an association with sexual violence outcomes were identified, including policies affecting alcohol pricing, alcohol outlet density, barroom management, sexist content in alcohol marketing, and policies banning alcohol on campus and in substance-free dorms. We identify other policy areas with evidence of an impact on related outcomes and risk factors that may also hold potential as a preventative approach for sexual violence perpetration. Evidence from the current review suggests that alcohol policy may represent one promising avenue for the prevention of sexual violence perpetration at the community level, but additional research is needed to directly examine effects on sexual violence outcomes. PMID:25403447

  5. Fostering cooperation in power asymmetrical water systems by the use of direct release rules and index-based insurance schemes

    Science.gov (United States)

    Denaro, Simona; Castelletti, Andrea; Giuliani, Matteo; Characklis, Gregory W.

    2018-05-01

    In river basin systems, power asymmetry is often responsible of inefficient and unbalanced water allocations. Climate change and anthropogenic pressure will possibly exacerbate such disparities as the dominant party controls an increasingly limited shared resource. In this context, the deployment of cooperation mechanisms giving greater consideration to a balanced distribution of the benefits, while improving system-wide efficiency, may be desirable. This often implies the intervention of a third party (e.g., the river basin water authority) imposing normative constraints (e.g., a minimum release) on the party in the dominant position. However, this imposition will be more acceptable to the dominant party if coupled with some form of compensation. For a public agency, compensation may be burdensome, especially when the allowance is triggered by natural events whose timing and magnitude are highly uncertain. In this context, index-based insurance contracts may represent a viable alternative and reduce the cost of achieving socially desirable outcomes. In this paper, we develop a hybrid cooperation mechanism composed of i) a direct normative constraint imposed by a regulator, and ii) an indirect financial tool, an index-based insurance contract, to be used as a compensation measure. The approach is developed for the Lake Como multi-purpose water system, Italy: a complex Alpine river basin, supporting several hydropower reservoirs and finally flowing into a regulated lake which supplies water to several downstream uses, mostly irrigated agriculture. The system is characterized by a manifest geographic power asymmetry: the upstream hydropower companies are free to release their stored water in time irrespective of the timing of the downstream demands. This situation can lead to financial losses by the downstream users and undesirable social outcomes. Results suggest that financial instruments may offer a reliable and relatively inexpensive alternative to other forms of

  6. Gastrin-releasing peptide in the porcine pancreas

    DEFF Research Database (Denmark)

    Holst, J J; Poulsen, Steen Seier

    1987-01-01

    to consist of one main form, namely the 27-amino acid peptide originally extracted from porcine stomach, and small amounts of a C-terminal fragment identical with the C-terminal 10-amino acid peptide. Gastrin-releasing peptide-like immunoreactivity released from the isolated perfused porcine pancreas during...... electrical vagal stimulation was shown by gel filtration to consist of the same two forms. By use of immunocytochemical techniques employing an antiserum directed against its N terminus, GRP was localized to varicose nerve fibers in close association with the exocrine tissue of the porcine pancreas...... in particular. Some fibers were found penetrating into pancreatic islets also. Immunoreactive nerve cell bodies as well as fibers were found within intrapancreatic ganglia. The potency of GRP in stimulating exocrine as well as endocrine secretion from the porcine pancreas, its presence in close contact...

  7. Preparation of acetaminophen capsules containing beads prepared by hot-melt direct blend coating.

    Science.gov (United States)

    Pham, Loan; Christensen, John M

    2014-02-01

    Twelve hydrophobic coating agents were assessed for their effects on drug release after coating sugar cores by a flexible hot-melt coating method using direct blending. Drug-containing pellets were also produced and used as cores. The cores were coated with single or double wax layers containing acetaminophen (APAP). The harder the wax, the slower the resultant drug releases from single-coated beads. Wax coating can be deposited on cores up to 28% of the beads final weight and reaching 58% with wax and drug. Carnauba-coated beads dissolved in approximately 6 h releasing 80% of the loaded drug. Applying another wax layer extended drug release over 20 h, while still delivering 80% of the loaded drug. When drug-containing pellets (33-58% drug loading) were used as cores, double wax-coated pellets exhibited a near zero-order drug release for 16 h, releasing 80% of the loaded drug delivering 18 mg/h. The simple process of hot-melt coating by direct blending of pellet-containing drug-coated formulations provides excellent options for immediate and sustained release formulations when higher lipid coating or drug loading is warranted. Predicted plasma drug concentration time profiles using convolution and in vitro drug release properties of the beads were performed for optimal formulations.

  8. In Search for a Pronatalist Population Policy for Turkey

    Directory of Open Access Journals (Sweden)

    Yusuf YÜKSEL

    2015-06-01

    Full Text Available Turkey has witnessed high fertility rates and low mortality rates until 2000s. Young population structure, need for infrastructure for growing population and reproductive health issues were always on the agenda of policy makers throughout the history of Turkey. After the decline in total fertility rate below replacement level, vibrant discussions and search for a new policy framework began to be visible in the recent years. After the establishment of new Republic in Turkey in 1923 pronatalist policies were active until the beginning 1960s. After the First Development Plan in 1962, policy shift was towards an antinatalist direction until 2000. After a short period between 2000 and 2012 which can not be put any category in terms of fertility policy government clearly declared its position favouring pronatalist policies and mobilised bureaucracy for developing new policy options. This paper summarizes the fertility policies and demographic transition of Turkey and evaluates possible policy options

  9. Formulation and In vitro/In vivo Evaluation of Sustained Release ...

    African Journals Online (AJOL)

    HP

    ISSN: 1596-5996 (print); 1596-9827 (electronic). © Pharmacotherapy ... (DHL). Methods: DHL tablets were prepared by direct compression and consisted of .... subjected to 3D response surface methodology to determine the .... Table 3: Release of diltiazem HCl from the test formulations as per factorial design. Formulation ...

  10. Review of Policy Documents for Nuclear Safety and Regulation

    International Nuclear Information System (INIS)

    Kim, Woong Sik; Choi, Kwang Sik; Choi, Young Sung; Kim, Hho Jung; Kim, Ho Ki

    2006-01-01

    The goal of regulation is to protect public health and safety as well as environment from radiological hazards that may occur as a result of the use of atomic energy. In September 1994, the Korean government issued the Nuclear Safety Policy Statement (NSPS) to establish policy goals of maintaining and achieving high-level of nuclear safety and also help the public understand the national policy and a strong will of the government toward nuclear safety. It declares the importance of establishing safety culture in nuclear community and also specifies five nuclear regulatory principles (Independence, Openness, Clarity, Efficiency and Reliability) and provides the eleven regulatory policy directions. In 2001, the Nuclear Safety Charter was declared to make the highest goal of safety in driving nuclear business clearer; to encourage atomic energy- related institutions and workers to keep in mind the mission and responsibility for assuring safety; to guarantee public confidence in related organizations. The Ministry of Science and Technology (MOST) also issues Yearly Regulatory Policy Directions at the beginning of every year. Recently, the third Atomic Energy Promotion Plan (2007-2011) has been established. It becomes necessary for the relevant organizations to prepare the detailed plans on such areas as nuclear development, safety management, regulation, etc. This paper introduces a multi-level structure of nuclear safety and regulation policy documents in Korea and presents some improvements necessary for better application of the policies

  11. Review of Policy Documents for Nuclear Safety and Regulation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woong Sik; Choi, Kwang Sik; Choi, Young Sung; Kim, Hho Jung; Kim, Ho Ki [Korea Institute of Nuclear Safety, Taejon (Korea, Republic of)

    2006-07-01

    The goal of regulation is to protect public health and safety as well as environment from radiological hazards that may occur as a result of the use of atomic energy. In September 1994, the Korean government issued the Nuclear Safety Policy Statement (NSPS) to establish policy goals of maintaining and achieving high-level of nuclear safety and also help the public understand the national policy and a strong will of the government toward nuclear safety. It declares the importance of establishing safety culture in nuclear community and also specifies five nuclear regulatory principles (Independence, Openness, Clarity, Efficiency and Reliability) and provides the eleven regulatory policy directions. In 2001, the Nuclear Safety Charter was declared to make the highest goal of safety in driving nuclear business clearer; to encourage atomic energy- related institutions and workers to keep in mind the mission and responsibility for assuring safety; to guarantee public confidence in related organizations. The Ministry of Science and Technology (MOST) also issues Yearly Regulatory Policy Directions at the beginning of every year. Recently, the third Atomic Energy Promotion Plan (2007-2011) has been established. It becomes necessary for the relevant organizations to prepare the detailed plans on such areas as nuclear development, safety management, regulation, etc. This paper introduces a multi-level structure of nuclear safety and regulation policy documents in Korea and presents some improvements necessary for better application of the policies.

  12. Newly released EIA-law. A palette of wishes?; Das neue UVP-Recht. Ein Wunschkonzert?

    Energy Technology Data Exchange (ETDEWEB)

    Feldmann, Ulrike

    2015-05-15

    The EU-directive on Environmental Impact Assessment (EIA) for certain public and private projects was once again amended in 2014 after controversial discussions, three previous modifications during 1985 and 2010 and an aggregation of all amendments within the EU-EIA-2011/92 directive. This newly released EU-EIA-directive 2014/52/EU (hereinafter RL 2014/52) is published within the EU-official journal EU L 124 p. 1 from 25.04.2014, came into force on 15. May 2014 and has to be adopted into international law until 16.05.2017. The modifications made are also valid, apart from certain exceptions, for licensing procedures (including decommissioning of nuclear power plants) in the field of nuclear energy, as far as they might have possible, significant environmental effects. The European EIA directive's 30th ''anniversary'' on 27.06.2015 raises the question, which substantial changes will come soon along with the newly released EU-EIA law. All in all it seems like if authorities and industry might get along with the newly released EU-EIA regulations. The responsible Federal Ministry for the Environment is already working on a first preliminary draft. It is under consideration if the EIA-regulation should be submitted additionally, beyond required amendments by EU-law, to a general revision. EIA-law remains exciting.

  13. National Space Weather Program Releases Strategy for the New Decade

    Science.gov (United States)

    Williamson, Samuel P.; Babcock, Michael R.; Bonadonna, Michael F.

    2010-12-01

    The National Space Weather Program (NSWP; http://www.nswp.gov) is a U.S. federal government interagency program established by the Office of the Federal Coordinator for Meteorology (OFCM) in 1995 to coordinate, collaborate, and leverage capabilities across stakeholder agencies, including space weather researchers, service providers, users, policy makers, and funding agencies, to improve the performance of the space weather enterprise for the United States and its international partners. Two important documents released in recent months have established a framework and the vision, goals, and strategy to move the enterprise forward in the next decade. The U.S. federal agency members of the NSWP include the departments of Commerce, Defense, Energy, Interior, State, and Transportation, plus NASA, the National Science Foundation, and observers from the White House Office of Science and Technology Policy (OSTP) and the Office of Management and Budget (OMB). The OFCM is also working with the Department of Homeland Security's Federal Emergency Management Agency to formally join the program.

  14. Health Policy Training: A Review of the Literature.

    Science.gov (United States)

    Heiman, Harry J; Smith, L Lerissa; McKool, Marissa; Mitchell, Denise N; Roth Bayer, Carey

    2015-12-23

    The context within which health care and public health systems operate is framed by health policies. There is growing consensus about the need for increased health policy leadership and a health professional workforce prepared to assume these leadership roles. At the same time, there is strong evidence supporting the need for a broader policy lens and the need to intentionally target health disparities. We reviewed the published literature between 1983 and 2013 regarding health policy training. From 5124 articles identified, 33 met inclusion criteria. Articles varied across common themes including target audience, goal(s), health policy definition, and core curricular content. The majority of articles were directed to medical or nursing audiences. Most articles framed health policy as health care policy and only a small number adopted a broader health in all policies definition. Few articles specifically addressed vulnerable populations or health disparities. The need for more rigorous research and evaluation to inform health policy training is compelling. Providing health professionals with the knowledge and skills to engage and take leadership roles in health policy will require training programs to move beyond their limited health care-oriented health policy framework to adopt a broader health and health equity in all policies approach.

  15. Health Policy Training: A Review of the Literature

    Directory of Open Access Journals (Sweden)

    Harry J. Heiman

    2015-12-01

    Full Text Available The context within which health care and public health systems operate is framed by health policies. There is growing consensus about the need for increased health policy leadership and a health professional workforce prepared to assume these leadership roles. At the same time, there is strong evidence supporting the need for a broader policy lens and the need to intentionally target health disparities. We reviewed the published literature between 1983 and 2013 regarding health policy training. From 5124 articles identified, 33 met inclusion criteria. Articles varied across common themes including target audience, goal(s, health policy definition, and core curricular content. The majority of articles were directed to medical or nursing audiences. Most articles framed health policy as health care policy and only a small number adopted a broader health in all policies definition. Few articles specifically addressed vulnerable populations or health disparities. The need for more rigorous research and evaluation to inform health policy training is compelling. Providing health professionals with the knowledge and skills to engage and take leadership roles in health policy will require training programs to move beyond their limited health care-oriented health policy framework to adopt a broader health and health equity in all policies approach.

  16. Drug policy in United States of America

    OpenAIRE

    Stahl, Edmundo G.; Médico internista, President and Chief Executive Officer, LatAmScience. Florida, USA.

    2009-01-01

    The USA federal prescription drug policies are inconsistent. The federal government regulates the development, production, marketing and safety of prescription drugs in the country through various legal mechanisms as well as private and governmental institutions. Patent laws also play an important role in this process protecting the pharmaceutical industry. The government has no direct mechanism to control prices of prescription drugs nor does it have a policy to cover the whole US popula...

  17. Bacteria-Triggered Release of Antimicrobial Agents

    DEFF Research Database (Denmark)

    Komnatnyy, Vitaly V.; Chiang, Wen-Chi; Tolker-Nielsen, Tim

    2014-01-01

    Medical devices employed in healthcare practice are often susceptible to microbial contamination. Pathogenic bacteria may attach themselves to device surfaces of catheters or implants by formation of chemically complex biofilms, which may be the direct cause of device failure. Extracellular...... bacterial lipases are particularly abundant at sites of infection. Herein it is shown how active or proactive compounds attached to polymeric surfaces using lipase‐sensitive linkages, such as fatty acid esters or anhydrides, may be released in response to infection. Proof‐of‐concept of the responsive...

  18. Bacteria‐Triggered Release of Antimicrobial Agents

    DEFF Research Database (Denmark)

    Komnatnyy, Vitaly V.; Chiang, Wen‐Chi; Tolker‐Nielsen, Tim

    2014-01-01

    Medical devices employed in healthcare practice are often susceptible to microbial contamination. Pathogenic bacteria may attach themselves to device surfaces of catheters or implants by formation of chemically complex biofilms, which may be the direct cause of device failure. Extracellular...... bacterial lipases are particularly abundant at sites of infection. Herein it is shown how active or proactive compounds attached to polymeric surfaces using lipase‐sensitive linkages, such as fatty acid esters or anhydrides, may be released in response to infection. Proof‐of‐concept of the responsive...

  19. Evaluation of Radionuclide Release from Aluminum-Based SNF in Basin Storage

    International Nuclear Information System (INIS)

    Sindelar, R.L.; Burke, S.D.; Howell, J.P.

    1998-09-01

    This report provides an evaluation of the release rates of radionuclides from breached A1-SNF assemblies and evaluates the effect of direct storage of breached fuel at a conservative upper bound reference condition on the SRS basin water activity levels

  20. The OPL Access Control Policy Language

    Science.gov (United States)

    Alm, Christopher; Wolf, Ruben; Posegga, Joachim

    Existing policy languages suffer from a limited ability of directly and elegantly expressing high-level access control principles such as history-based separation of duty [22], binding of duty [26], context constraints [24], Chinese wall properties [10], and obligations [20]. It is often difficult to extend a language in order to retrofit these features once required or it is necessary to use complicated and complex language constructs to express such concepts. The latter, however, is cumbersome and error-prone for humans dealing with policy administration.