WorldWideScience

Sample records for relative importance numbers

  1. Some relations between entropy and approximation numbers

    Institute of Scientific and Technical Information of China (English)

    郑志明

    1999-01-01

    A general result is obtained which relates the entropy numbers of compact maps on Hilbert space to its approximation numbers. Compared with previous works in this area, it is particularly convenient for dealing with the cases where the approximation numbers decay rapidly. A nice estimation between entropy and approximation numbers for noncompact maps is given.

  2. The importance of copy number variation in congenital heart disease

    Science.gov (United States)

    Costain, Gregory; Silversides, Candice K; Bassett, Anne S

    2016-01-01

    Congenital heart disease (CHD) is the most common class of major malformations in humans. The historical association with large chromosomal abnormalities foreshadowed the role of submicroscopic rare copy number variations (CNVs) as important genetic causes of CHD. Recent studies have provided robust evidence for these structural variants as genome-wide contributors to all forms of CHD, including CHD that appears isolated without extra-cardiac features. Overall, a CNV-related molecular diagnosis can be made in up to one in eight patients with CHD. These include de novo and inherited variants at established (chromosome 22q11.2), emerging (chromosome 1q21.1), and novel loci across the genome. Variable expression of rare CNVs provides support for the notion of a genetic spectrum of CHD that crosses traditional anatomic classification boundaries. Clinical genetic testing using genome-wide technologies (e.g., chromosomal microarray analysis) is increasingly employed in prenatal, paediatric and adult settings. CNV discoveries in CHD have translated to changes to clinical management, prognostication and genetic counselling. The convergence of findings at individual gene and at pathway levels is shedding light on the mechanisms that govern human cardiac morphogenesis. These clinical and research advances are helping to inform whole-genome sequencing, the next logical step in delineating the genetic architecture of CHD. PMID:28706735

  3. Nonclassicality in phase-number uncertainty relations

    International Nuclear Information System (INIS)

    Matia-Hernando, Paloma; Luis, Alfredo

    2011-01-01

    We show that there are nonclassical states with lesser joint fluctuations of phase and number than any classical state. This is rather paradoxical since one would expect classical coherent states to be always of minimum uncertainty. The same result is obtained when we replace phase by a phase-dependent field quadrature. Number and phase uncertainties are assessed using variance and Holevo relation.

  4. Nonclassicality in phase-number uncertainty relations

    Energy Technology Data Exchange (ETDEWEB)

    Matia-Hernando, Paloma; Luis, Alfredo [Departamento de Optica, Facultad de Ciencias Fisicas, Universidad Complutense, 28040 Madrid (Spain)

    2011-12-15

    We show that there are nonclassical states with lesser joint fluctuations of phase and number than any classical state. This is rather paradoxical since one would expect classical coherent states to be always of minimum uncertainty. The same result is obtained when we replace phase by a phase-dependent field quadrature. Number and phase uncertainties are assessed using variance and Holevo relation.

  5. Copy number variation plays an important role in clinical epilepsy

    Science.gov (United States)

    Olson, Heather; Shen, Yiping; Avallone, Jennifer; Sheidley, Beth R.; Pinsky, Rebecca; Bergin, Ann M.; Berry, Gerard T.; Duffy, Frank H.; Eksioglu, Yaman; Harris, David J.; Hisama, Fuki M.; Ho, Eugenia; Irons, Mira; Jacobsen, Christina M.; James, Philip; Kothare, Sanjeev; Khwaja, Omar; Lipton, Jonathan; Loddenkemper, Tobias; Markowitz, Jennifer; Maski, Kiran; Megerian, J. Thomas; Neilan, Edward; Raffalli, Peter C.; Robbins, Michael; Roberts, Amy; Roe, Eugene; Rollins, Caitlin; Sahin, Mustafa; Sarco, Dean; Schonwald, Alison; Smith, Sharon E.; Soul, Janet; Stoler, Joan M.; Takeoka, Masanori; Tan, Wen-Han; Torres, Alcy R.; Tsai, Peter; Urion, David K.; Weissman, Laura; Wolff, Robert; Wu, Bai-Lin; Miller, David T.; Poduri, Annapurna

    2015-01-01

    Objective To evaluate the role of copy number abnormalities detectable by chromosomal microarray (CMA) testing in patients with epilepsy at a tertiary care center. Methods We identified patients with ICD-9 codes for epilepsy or seizures and clinical CMA testing performed between October 2006 and February 2011 at Boston Children’s Hospital. We reviewed medical records and included patients meeting criteria for epilepsy. We phenotypically characterized patients with epilepsy-associated abnormalities on CMA. Results Of 973 patients who had CMA and ICD-9 codes for epilepsy or seizures, 805 patients satisfied criteria for epilepsy. We observed 437 copy number variants (CNVs) in 323 patients (1–4 per patient), including 185 (42%) deletions and 252 (58%) duplications. Forty (9%) were confirmed de novo, 186 (43%) were inherited, and parental data were unavailable for 211 (48%). Excluding full chromosome trisomies, CNV size ranged from 18 kb to 142 Mb, and 34% were over 500 kb. In at least 40 cases (5%), the epilepsy phenotype was explained by a CNV, including 29 patients with epilepsy-associated syndromes and 11 with likely disease-associated CNVs involving epilepsy genes or “hotspots.” We observed numerous recurrent CNVs including 10 involving loss or gain of Xp22.31, a region described in patients with and without epilepsy. Interpretation Copy number abnormalities play an important role in patients with epilepsy. Given that the diagnostic yield of CMA for epilepsy patients is similar to the yield in autism spectrum disorders and in prenatal diagnosis, for which published guidelines recommend testing with CMA, we recommend the implementation of CMA in the evaluation of unexplained epilepsy. PMID:24811917

  6. A Research on a Certain Family of Numbers and Polynomials Related to Stirling Numbers, Central Factorial Numbers, and Euler Numbers

    Directory of Open Access Journals (Sweden)

    J. Y. Kang

    2013-01-01

    Full Text Available Recently, many mathematicians have studied different kinds of the Euler, Bernoulli, and Genocchi numbers and polynomials. In this paper, we give another definition of polynomials Ũn(x. We observe an interesting phenomenon of “scattering” of the zeros of the polynomials Ũn(x in complex plane. We find out some identities and properties related to polynomials Ũn(x. Finally, we also derive interesting relations between polynomials Ũn(x, Stirling numbers, central factorial numbers, and Euler numbers.

  7. Surgery in cerebral metastases: Are numbers so important?

    Directory of Open Access Journals (Sweden)

    Alessandro Agnoletti

    2014-01-01

    The selection of candidates for surgery requires several considerations and entails the success rate of this treatment. In patients with the multiple lesions who fulfilled the selection criteria we observed a nevertheless satisfying success after the operation. Our results imply that surgery may be applied also in selected patients with more diffuse intracranial disease. A pre-operative accurate patient selection is related to acceptable quality-of-life following the operation even in cases of multiple MTS.

  8. The Relative Importance of the European Languages

    DEFF Research Database (Denmark)

    Hjorth-Andersen, Christian

    the relevant measure GNP rather than the population measure usually preferred by linguists and politicians. The results are quite dramatic as English can be shown to be completely dominant. In the second part of the paper, I look at the relative importance of the European languages in Europe. In order to put...

  9. The relative importance of inheritances in Norway

    OpenAIRE

    Johansson, Marianne Lefsaker

    2014-01-01

    In a very influential paper, Piketty (2011) finds that inherited wealth is of increasing importance in France. He describes a U-shaped pattern in the long-run development of inheritance flows. Two driving factors in this development are the relative ratio of wealth of the deceased to wealth of the living, and the wealth-income ratio. In periods with high economic growth, wealth of the past is weakened and inheritances as share of national income decreases. As soon as growth declines, however,...

  10. The Increasing Importance of Employee Relations

    Science.gov (United States)

    Keckley, Paul

    1977-01-01

    Surveys corporate public relations executives for information about their concern for and involvement with employee relations programming in their organizations and analyzes current public relations education as it relates to these findings. Available from: Public Relations Review, Ray Hiebert, Dean, College of Journalism, University of Maryland,…

  11. Baryon number violation and novel canonical anti-commutation relations

    Science.gov (United States)

    Fujikawa, Kazuo; Tureanu, Anca

    2018-02-01

    The possible neutron-antineutron oscillation is described by an effective quadratic Lagrangian analogous to the BCS theory. It is shown that the conventional equal-time anti-commutation relations of the neutron variable n (t , x →) are modified by the baryon number violating terms. This is established by the Bjorken-Johnson-Low prescription and also by the canonical quantization combined with equations of motion. This novel canonical behavior can give rise to an important physical effect, which is illustrated by analyzing the Lagrangian that violates the baryon number but gives rise to the degenerate effective Majorana fermions and thus no neutron-antineutron oscillation. Technically, this model is neatly treated using a relativistic analogue of the Bogoliubov transformation.

  12. Genome-wide association study identified copy number variants important for appendicular lean mass.

    Science.gov (United States)

    Ran, Shu; Liu, Yong-Jun; Zhang, Lei; Pei, Yufang; Yang, Tie-Lin; Hai, Rong; Han, Ying-Ying; Lin, Yong; Tian, Qing; Deng, Hong-Wen

    2014-01-01

    Skeletal muscle is a major component of the human body. Age-related loss of muscle mass and function contributes to some public health problems such as sarcopenia and osteoporosis. Skeletal muscle, mainly composed of appendicular lean mass (ALM), is a heritable trait. Copy number variation (CNV) is a common type of human genome variant which may play an important role in the etiology of many human diseases. In this study, we performed genome-wide association analyses of CNV for ALM in 2,286 Caucasian subjects. We then replicated the major findings in 1,627 Chinese subjects. Two CNVs, CNV1191 and CNV2580, were detected to be associated with ALM (p = 2.26×10(-2) and 3.34×10(-3), respectively). In the Chinese replication sample, the two CNVs achieved p-values of 3.26×10(-2) and 0.107, respectively. CNV1191 covers a gene, GTPase of the immunity-associated protein family (GIMAP1), which is important for skeletal muscle cell survival/death in humans. CNV2580 is located in the Serine hydrolase-like protein (SERHL) gene, which plays an important role in normal peroxisome function and skeletal muscle growth in response to mechanical stimuli. In summary, our study suggested two novel CNVs and the related genes that may contribute to variation in ALM.

  13. Genome-wide association study identified copy number variants important for appendicular lean mass.

    Directory of Open Access Journals (Sweden)

    Shu Ran

    Full Text Available Skeletal muscle is a major component of the human body. Age-related loss of muscle mass and function contributes to some public health problems such as sarcopenia and osteoporosis. Skeletal muscle, mainly composed of appendicular lean mass (ALM, is a heritable trait. Copy number variation (CNV is a common type of human genome variant which may play an important role in the etiology of many human diseases. In this study, we performed genome-wide association analyses of CNV for ALM in 2,286 Caucasian subjects. We then replicated the major findings in 1,627 Chinese subjects. Two CNVs, CNV1191 and CNV2580, were detected to be associated with ALM (p = 2.26×10(-2 and 3.34×10(-3, respectively. In the Chinese replication sample, the two CNVs achieved p-values of 3.26×10(-2 and 0.107, respectively. CNV1191 covers a gene, GTPase of the immunity-associated protein family (GIMAP1, which is important for skeletal muscle cell survival/death in humans. CNV2580 is located in the Serine hydrolase-like protein (SERHL gene, which plays an important role in normal peroxisome function and skeletal muscle growth in response to mechanical stimuli. In summary, our study suggested two novel CNVs and the related genes that may contribute to variation in ALM.

  14. Egg number-egg size: an important trade-off in parasite life history strategies.

    Science.gov (United States)

    Cavaleiro, Francisca I; Santos, Maria J

    2014-03-01

    Parasites produce from just a few to many eggs of variable size, but our understanding of the factors driving variation in these two life history traits at the intraspecific level is still very fragmentary. This study evaluates the importance of performing multilevel analyses on egg number and egg size, while characterising parasite life history strategies. A total of 120 ovigerous females of Octopicola superba (Copepoda: Octopicolidae) (one sample (n=30) per season) were characterised with respect to different body dimensions (total length; genital somite length) and measures of reproductive effort (fecundity; mean egg diameter; total reproductive effort; mean egg sac length). While endoparasites are suggested to follow both an r- and K-strategy simultaneously, the evidence found in this and other studies suggests that environmental conditions force ectoparasites into one of the two alternatives. The positive and negative skewness of the distributions of fecundity and mean egg diameter, respectively, suggest that O. superba is mainly a K-strategist (i.e. produces a relatively small number of large, well provisioned eggs). Significant sample differences were recorded concomitantly for all body dimensions and measures of reproductive effort, while a general linear model detected a significant influence of season*parasite total length in both egg number and size. This evidence suggests adaptive phenotypic plasticity in body dimensions and size-mediated changes in egg production. Seasonal changes in partitioning of resources between egg number and size resulted in significant differences in egg sac length but not in total reproductive effort. Evidence for a trade-off between egg number and size was found while controlling for a potential confounding effect of parasite total length. However, this trade-off became apparent only at high fecundity levels, suggesting a state of physiological exhaustion. Copyright © 2014 Australian Society for Parasitology Inc. Published

  15. Number of generations related to coupling constants by confusion

    International Nuclear Information System (INIS)

    Bennett, D.L.; Nielsen, H.B.

    1987-01-01

    In the context of random dynamics, the mechanism of confusion is used to obtain a relation between the number of generations and standard model coupling constants. Preliminary results predict the existence of four generations. (orig.)

  16. Froude Number is the Single Most Important Hydraulic Parameter for Salmonid Spawning Habitat.

    Science.gov (United States)

    Gillies, E.; Moir, H. J.

    2015-12-01

    Many gravel-bed rivers exhibit historic straightening or embanking, reducing river complexity and the available habitat for key species such as salmon. A defensible method for predicting salmonid spawning habitat is an important tool for anyone engaged in assessing a river restoration. Most empirical methods to predict spawning habitat use lookup tables of depth, velocity and substrate. However, natural site selection is different: salmon must pick a location where they can successfully build a redd, and where eggs have a sufficient survival rate. Also, using dimensional variables, such as depth and velocity, is problematic: spawning occurs in rivers of differing size, depth and velocity range. Non-dimensional variables have proven useful in other branches of fluid dynamics, and instream habitat is no different. Empirical river data has a high correlation between observed salmon redds and Froude number, without insight into why. Here we present a physics based model of spawning and bedform evolution, which shows that Froude number is indeed a rational choice for characterizing the bedform, substrate, and flow necessary for spawning. It is familiar for Froude to characterize surface waves, but Froude also characterizes longitudinal bedform in a mobile bed river. We postulate that these bedforms and their hydraulics perform two roles in salmonid spawning: allowing transport of clasts during redd building, and oxygenating eggs. We present an example of this Froude number and substrate based habitat characterization on a Scottish river for which we have detailed topography at several stages during river restoration and subsequent evolution of natural processes. We show changes to the channel Froude regime as a result of natural process and validate habitat predictions against redds observed during 2014 and 2015 spawning seasons, also relating this data to the Froude regime in other, nearby, rivers. We discuss the use of the Froude spectrum in providing an indicator of

  17. On the Relation Between Grammatical Number and Cardinal Numbers in Development

    Directory of Open Access Journals (Sweden)

    Barbara W Sarnecka

    2014-10-01

    Full Text Available This mini-review focuses on the question of how the grammatical number system of a child’s language may help the child learn the meanings of cardinal number words (e.g., ‘one’ and ‘two’. Evidence from young children learning English, Russian, Japanese, Mandarin, Slovenian or Saudi Arabic suggests that trajectories of number-word learning differ for children learning different languages. Children learning English, which distinguishes between singular and plural, seem to learn the meaning of the cardinal number ‘one’ earlier than children learning Japanese or Mandarin, which have very little singular/plural marking. Similarly, children whose languages have a singular/dual/plural system (Slovenian and Saudi Arabic learn the meaning of ‘two’ earlier than English-speaking children. This relation between grammatical and cardinal number may shed light on how humans acquire cardinal-number concepts. There is an ongoing debate about whether mental symbols for small cardinalities (concepts for ‘oneness,’ ‘twoness,’ etc. are innate or learned. Although an effect of grammatical number on number-word learning does not rule out nativist accounts, it seems more consistent with constructivist accounts, which portray the number-learning process as one that requires significant conceptual change.

  18. On the relation between grammatical number and cardinal numbers in development.

    Science.gov (United States)

    Sarnecka, Barbara W

    2014-01-01

    This mini-review focuses on the question of how the grammatical number system of a child's language may help the child learn the meanings of cardinal number words (e.g., "one" and "two"). Evidence from young children learning English, Russian, Japanese, Mandarin, Slovenian, or Saudi Arabic suggests that trajectories of number-word learning differ for children learning different languages. Children learning English, which distinguishes between singular and plural, seem to learn the meaning of the cardinal number "one" earlier than children learning Japanese or Mandarin, which have very little singular/plural marking. Similarly, children whose languages have a singular/dual/plural system (Slovenian and Saudi Arabic) learn the meaning of "two" earlier than English-speaking children. This relation between grammatical and cardinal number may shed light on how humans acquire cardinal-number concepts. There is an ongoing debate about whether mental symbols for small cardinalities (concepts for "oneness," "twoness," etc.) are innate or learned. Although an effect of grammatical number on number-word learning does not rule out nativist accounts, it seems more consistent with constructivist accounts, which portray the number-learning process as one that requires significant conceptual change.

  19. Optimization of approximate decision rules relative to number of misclassifications

    KAUST Repository

    Amin, Talha M.; Chikalov, Igor; Moshkov, Mikhail; Zielosko, Beata

    2012-01-01

    In the paper, we study an extension of dynamic programming approach which allows optimization of approximate decision rules relative to the number of misclassifications. We introduce an uncertainty measure J(T) which is a difference between the number of rows in a decision table T and the number of rows with the most common decision for T. For a nonnegative real number γ, we consider γ-decision rules that localize rows in subtables of T with uncertainty at most γ. The presented algorithm constructs a directed acyclic graph Δγ(T). Based on this graph we can describe the whole set of so-called irredundant γ-decision rules. We can optimize rules from this set according to the number of misclassifications. Results of experiments with decision tables from the UCI Machine Learning Repository are presented. © 2012 The authors and IOS Press. All rights reserved.

  20. Optimization of approximate decision rules relative to number of misclassifications

    KAUST Repository

    Amin, Talha

    2012-12-01

    In the paper, we study an extension of dynamic programming approach which allows optimization of approximate decision rules relative to the number of misclassifications. We introduce an uncertainty measure J(T) which is a difference between the number of rows in a decision table T and the number of rows with the most common decision for T. For a nonnegative real number γ, we consider γ-decision rules that localize rows in subtables of T with uncertainty at most γ. The presented algorithm constructs a directed acyclic graph Δγ(T). Based on this graph we can describe the whole set of so-called irredundant γ-decision rules. We can optimize rules from this set according to the number of misclassifications. Results of experiments with decision tables from the UCI Machine Learning Repository are presented. © 2012 The authors and IOS Press. All rights reserved.

  1. Optimization of Approximate Inhibitory Rules Relative to Number of Misclassifications

    KAUST Repository

    Alsolami, Fawaz

    2013-10-04

    In this work, we consider so-called nonredundant inhibitory rules, containing an expression “attribute:F value” on the right- hand side, for which the number of misclassifications is at most a threshold γ. We study a dynamic programming approach for description of the considered set of rules. This approach allows also the optimization of nonredundant inhibitory rules relative to the length and coverage. The aim of this paper is to investigate an additional possibility of optimization relative to the number of misclassifications. The results of experiments with decision tables from the UCI Machine Learning Repository show this additional optimization achieves a fewer misclassifications. Thus, the proposed optimization procedure is promising.

  2. Range and number-of-levels effects in derived and stated measures of attribute importance

    NARCIS (Netherlands)

    Verlegh, PWJ; Schifferstein, HNJ; Wittink, DR

    We study how the range of variation and the number of ttribute levels affect five measures of attribute importance: full profile conjoint estimates, ranges in attribute level attractiveness ratings. regression coefficients. graded paired comparisons. and self-reported ratings, We find that all

  3. The Stokes-Einstein relation at moderate Schmidt number.

    Science.gov (United States)

    Balboa Usabiaga, Florencio; Xie, Xiaoyi; Delgado-Buscalioni, Rafael; Donev, Aleksandar

    2013-12-07

    The Stokes-Einstein relation for the self-diffusion coefficient of a spherical particle suspended in an incompressible fluid is an asymptotic result in the limit of large Schmidt number, that is, when momentum diffuses much faster than the particle. When the Schmidt number is moderate, which happens in most particle methods for hydrodynamics, deviations from the Stokes-Einstein prediction are expected. We study these corrections computationally using a recently developed minimally resolved method for coupling particles to an incompressible fluctuating fluid in both two and three dimensions. We find that for moderate Schmidt numbers the diffusion coefficient is reduced relative to the Stokes-Einstein prediction by an amount inversely proportional to the Schmidt number in both two and three dimensions. We find, however, that the Einstein formula is obeyed at all Schmidt numbers, consistent with linear response theory. The mismatch arises because thermal fluctuations affect the drag coefficient for a particle due to the nonlinear nature of the fluid-particle coupling. The numerical data are in good agreement with an approximate self-consistent theory, which can be used to estimate finite-Schmidt number corrections in a variety of methods. Our results indicate that the corrections to the Stokes-Einstein formula come primarily from the fact that the particle itself diffuses together with the momentum. Our study separates effects coming from corrections to no-slip hydrodynamics from those of finite separation of time scales, allowing for a better understanding of widely observed deviations from the Stokes-Einstein prediction in particle methods such as molecular dynamics.

  4. Relative importance of the different radionuclides for radiological consequences

    International Nuclear Information System (INIS)

    Manesse, D.

    1984-12-01

    This paper tries, for several source-terms, to estimate the relative importance of the different families of radioactive products in the calculation of radiological consequences; the study takes place in the case of accidental situations of PWR reactors [fr

  5. Relative Importance for Linear Regression in R: The Package relaimpo

    OpenAIRE

    Groemping, Ulrike

    2006-01-01

    Relative importance is a topic that has seen a lot of interest in recent years, particularly in applied work. The R package relaimpo implements six different metrics for assessing relative importance of regressors in the linear model, two of which are recommended - averaging over orderings of regressors and a newly proposed metric (Feldman 2005) called pmvd. Apart from delivering the metrics themselves, relaimpo also provides (exploratory) bootstrap confidence intervals. This paper offers a b...

  6. Hospital-physician relations: the relative importance of economic, relational and professional attributes to organizational attractiveness

    Science.gov (United States)

    2014-01-01

    Background Belgian hospitals face a growing shortage of physicians and increasingly competitive market conditions. In this challenging environment hospitals are struggling to build effective hospital-physician relationships which are considered to be a critical determinant of organizational success. Methods Employed physicians of a University hospital were surveyed. Organizational attributes were identified through the literature and two focus groups. Variables were measured using validated questionnaires. Descriptive analyses and linear regression were used to test the model and relative importance analyses were performed. Results The selected attributes predict hospital attractiveness significantly (79.3%). The relative importance analysis revealed that hospital attractiveness is most strongly predicted by professional attributes (35.3%) and relational attributes (29.7%). In particular, professional development opportunities (18.8%), hospital prestige (16.5%), organizational support (17.2%) and leader support (9.3%) were found to be most important. Besides these non-economic aspects, the employed physicians indicated pay and financial benefits (7.4%) as a significant predictor of hospital attractiveness. Work-life balance and job security were not significantly related to hospital attractiveness. Conclusions This study shows that initiatives aimed at strengthening physicians’ positive perceptions of professional and relational aspects of practicing medicine in hospitals, while assuring satisfactory financial conditions, may offer useful avenues for increasing the level of perceived hospital attractiveness. Overall, hospitals are advised to use a differentiated approach to increase their attractiveness to physicians. PMID:24884491

  7. Hospital-physician relations: the relative importance of economic, relational and professional attributes to organizational attractiveness.

    Science.gov (United States)

    Trybou, Jeroen; Gemmel, Paul; Van Vaerenbergh, Yves; Annemans, Lieven

    2014-05-21

    Belgian hospitals face a growing shortage of physicians and increasingly competitive market conditions. In this challenging environment hospitals are struggling to build effective hospital-physician relationships which are considered to be a critical determinant of organizational success. Employed physicians of a University hospital were surveyed. Organizational attributes were identified through the literature and two focus groups. Variables were measured using validated questionnaires. Descriptive analyses and linear regression were used to test the model and relative importance analyses were performed. The selected attributes predict hospital attractiveness significantly (79.3%). The relative importance analysis revealed that hospital attractiveness is most strongly predicted by professional attributes (35.3%) and relational attributes (29.7%). In particular, professional development opportunities (18.8%), hospital prestige (16.5%), organizational support (17.2%) and leader support (9.3%) were found to be most important. Besides these non-economic aspects, the employed physicians indicated pay and financial benefits (7.4%) as a significant predictor of hospital attractiveness. Work-life balance and job security were not significantly related to hospital attractiveness. This study shows that initiatives aimed at strengthening physicians' positive perceptions of professional and relational aspects of practicing medicine in hospitals, while assuring satisfactory financial conditions, may offer useful avenues for increasing the level of perceived hospital attractiveness. Overall, hospitals are advised to use a differentiated approach to increase their attractiveness to physicians.

  8. Ensembles of a small number of conformations with relative populations

    Energy Technology Data Exchange (ETDEWEB)

    Vammi, Vijay, E-mail: vsvammi@iastate.edu; Song, Guang, E-mail: gsong@iastate.edu [Iowa State University, Bioinformatics and Computational Biology Program, Department of Computer Science (United States)

    2015-12-15

    In our previous work, we proposed a new way to represent protein native states, using ensembles of a small number of conformations with relative Populations, or ESP in short. Using Ubiquitin as an example, we showed that using a small number of conformations could greatly reduce the potential of overfitting and assigning relative populations to protein ensembles could significantly improve their quality. To demonstrate that ESP indeed is an excellent alternative to represent protein native states, in this work we compare the quality of two ESP ensembles of Ubiquitin with several well-known regular ensembles or average structure representations. Extensive amount of significant experimental data are employed to achieve a thorough assessment. Our results demonstrate that ESP ensembles, though much smaller in size comparing to regular ensembles, perform equally or even better sometimes in all four different types of experimental data used in the assessment, namely, the residual dipolar couplings, residual chemical shift anisotropy, hydrogen exchange rates, and solution scattering profiles. This work further underlines the significance of having relative populations in describing the native states.

  9. A practical relation between atomic numbers and alpha coefficients

    International Nuclear Information System (INIS)

    Lachance, G.R.

    1980-01-01

    A first approximation indicates that fundamental alpha coefficients for a given analyte vary as a function of the ratio of their respective atomic number raised to a power. This simple rule applies mainly at the limits (i.e., when the weight fraction of analyte i, Wsub(i) is of the order of 0.0 or 1.0) in cases of absorption and weak enhancement. The relation thus provides a means of generating coefficients for the system i-k from experimental data obtained on system i-j and a means of verifying experimental alphas, since arrays of coefficients must show a high degree of concordance. (author)

  10. The relative importance of ingestion for multiple pathway dose assessments

    International Nuclear Information System (INIS)

    Wicker, W.; Grogan, H.; Bergstroem, U.; Hoffman, O.

    1991-01-01

    The general purpose of this report is to examine the relative importance of ingestion pathways, and particularly food chain transport in overall dose assessment. The importance of ingestion pathways is examined for various release scenarios and radionuclides because the findings are expected to differ with circumstances. The degree to which contaminated food products contribute to the total dose will affect the importance of accuracy and uncertainty of food chain model predictions, which is the main thrust of the Biospheric Model Validation Study (BIOMOVS). This analysis requires that all modes of radiation exposure be examined, including inhalation, external exposure, and the various ingestion pathways. (2 figs., 2 tabs.)

  11. How math anxiety relates to number-space associations

    Directory of Open Access Journals (Sweden)

    Carrie Georges

    2016-09-01

    Full Text Available Given the considerable prevalence of math anxiety, it is important to identify the factors contributing to it in order to improve mathematical learning. Research on math anxiety typically focusses on the effects of more complex arithmetic skills. Recent evidence, however, suggests that deficits in basic numerical processing and spatial skills also constitute potential risk factors of math anxiety. Given these observations, we determined whether math anxiety also depends on the quality of spatial-numerical associations. Behavioural evidence for a tight link between numerical and spatial representations is given by the SNARC (spatial-numerical association of response codes effect, characterized by faster left-/right-sided responses for small/large digits respectively in binary classification tasks. We compared the strength of the SNARC effect between high and low math anxious individuals using the classical parity judgment task in addition to evaluating their spatial skills, arithmetic performance, working memory and inhibitory control. Greater math anxiety was significantly associated with stronger spatio-numerical interactions. This finding adds to the recent evidence supporting a link between math anxiety and basic numerical abilities and strengthens the idea that certain characteristics of low-level number processing such as stronger number-space associations constitute a potential risk factor of math anxiety.

  12. How Math Anxiety Relates to Number-Space Associations.

    Science.gov (United States)

    Georges, Carrie; Hoffmann, Danielle; Schiltz, Christine

    2016-01-01

    Given the considerable prevalence of math anxiety, it is important to identify the factors contributing to it in order to improve mathematical learning. Research on math anxiety typically focusses on the effects of more complex arithmetic skills. Recent evidence, however, suggests that deficits in basic numerical processing and spatial skills also constitute potential risk factors of math anxiety. Given these observations, we determined whether math anxiety also depends on the quality of spatial-numerical associations. Behavioral evidence for a tight link between numerical and spatial representations is given by the SNARC (spatial-numerical association of response codes) effect, characterized by faster left-/right-sided responses for small/large digits respectively in binary classification tasks. We compared the strength of the SNARC effect between high and low math anxious individuals using the classical parity judgment task in addition to evaluating their spatial skills, arithmetic performance, working memory and inhibitory control. Greater math anxiety was significantly associated with stronger spatio-numerical interactions. This finding adds to the recent evidence supporting a link between math anxiety and basic numerical abilities and strengthens the idea that certain characteristics of low-level number processing such as stronger number-space associations constitute a potential risk factor of math anxiety.

  13. Attachment insecurity and perceived importance of relational features

    NARCIS (Netherlands)

    Ren, D.; Arriaga, X.B.; Mahan, E.R.

    2017-01-01

    Chronic attachment insecurity can affect the outlook people have on relationships. This research examines how attachment insecurity relates to perceived importance of various features in a romantic relationship (e.g., intimacy, independence). Consistent with predictions, the results from Studies 1–3

  14. The Relative Importance of Job Factors: A New Measurement Approach.

    Science.gov (United States)

    Nealey, Stanley M.

    This paper reports on a new two-phase measurement technique that permits a direct comparison of the perceived relative importance of economic vs. non-economic factors in a job situation in accounting for personnel retention, the willingness to produce, and job satisfaction. The paired comparison method was used to measure the preferences of 91…

  15. Relative Importance of Common Bean Attributes and Variety ...

    African Journals Online (AJOL)

    The work assessed the relative importance of production and consumption attributes of different wealth groups of households and tested the effect of attribute preference and that of other factors on common bean variety demand in the drought areas of Eastern Kenya. Variety demand was conceptualized within the ...

  16. Relative Importance for Linear Regression in R: The Package relaimpo

    Directory of Open Access Journals (Sweden)

    Ulrike Gromping

    2006-09-01

    Full Text Available Relative importance is a topic that has seen a lot of interest in recent years, particularly in applied work. The R package relaimpo implements six different metrics for assessing relative importance of regressors in the linear model, two of which are recommended - averaging over orderings of regressors and a newly proposed metric (Feldman 2005 called pmvd. Apart from delivering the metrics themselves, relaimpo also provides (exploratory bootstrap confidence intervals. This paper offers a brief tutorial introduction to the package. The methods and relaimpo’s functionality are illustrated using the data set swiss that is generally available in R. The paper targets readers who have a basic understanding of multiple linear regression. For the background of more advanced aspects, references are provided.

  17. Radioactivity measurement in imported food and food related items

    International Nuclear Information System (INIS)

    Sombrito, E.Z.; Santos, F.L.; Rosa, A.M. de la; Tangonan, M.C.; Bulos, A.D.; Nuguid, Z.F.

    1989-01-01

    The Philippine Nuclear Research Institute (PNRI), formerly Philippine Atomic Energy Commission (PAEC) undertook the radioactivity monitoring of imported food and food-related products after the Chernobyl Plant accident in April 1986. Food samples were analyzed for 137 Cs and 134 Cs by gamma spectral method of analysis. This report deals with the measurement process and gives the result of the activity covering the period June 1986 to December 1987. (Auth.). 9 tabs., 7 figs., 4 refs

  18. Quantifying the relative irreplaceability of important bird and biodiversity areas.

    Science.gov (United States)

    Di Marco, Moreno; Brooks, Thomas; Cuttelod, Annabelle; Fishpool, Lincoln D C; Rondinini, Carlo; Smith, Robert J; Bennun, Leon; Butchart, Stuart H M; Ferrier, Simon; Foppen, Ruud P B; Joppa, Lucas; Juffe-Bignoli, Diego; Knight, Andrew T; Lamoreux, John F; Langhammer, Penny F; May, Ian; Possingham, Hugh P; Visconti, Piero; Watson, James E M; Woodley, Stephen

    2016-04-01

    World governments have committed to increase the global protected areas coverage by 2020, but the effectiveness of this commitment for protecting biodiversity depends on where new protected areas are located. Threshold- and complementarity-based approaches have been independently used to identify important sites for biodiversity. We brought together these approaches by performing a complementarity-based analysis of irreplaceability in important bird and biodiversity areas (IBAs), which are sites identified using a threshold-based approach. We determined whether irreplaceability values are higher inside than outside IBAs and whether any observed difference depends on known characteristics of the IBAs. We focused on 3 regions with comprehensive IBA inventories and bird distribution atlases: Australia, southern Africa, and Europe. Irreplaceability values were significantly higher inside than outside IBAs, although differences were much smaller in Europe than elsewhere. Higher irreplaceability values in IBAs were associated with the presence and number of restricted-range species; number of criteria under which the site was identified; and mean geographic range size of the species for which the site was identified (trigger species). In addition, IBAs were characterized by higher irreplaceability values when using proportional species representation targets, rather than fixed targets. There were broadly comparable results when measuring irreplaceability for trigger species and when considering all bird species, which indicates a good surrogacy effect of the former. Recently, the International Union for Conservation of Nature has convened a consultation to consolidate global standards for the identification of key biodiversity areas (KBAs), building from existing approaches such as IBAs. Our results informed this consultation, and in particular a proposed irreplaceability criterion that will allow the new KBA standard to draw on the strengths of both threshold- and

  19. Prey responses to predator chemical cues: disentangling the importance of the number and biomass of prey consumed.

    Directory of Open Access Journals (Sweden)

    Michael W McCoy

    Full Text Available To effectively balance investment in predator defenses versus other traits, organisms must accurately assess predation risk. Chemical cues caused by predation events are indicators of risk for prey in a wide variety of systems, but the relationship between how prey perceive risk in relation to the amount of prey consumed by predators is poorly understood. While per capita predation rate is often used as the metric of relative risk, studies aimed at quantifying predator-induced defenses commonly control biomass of prey consumed as the metric of risk. However, biomass consumed can change by altering either the number or size of prey consumed. In this study we determine whether phenotypic plasticity to predator chemical cues depends upon prey biomass consumed, prey number consumed, or both. We examine the growth response of red-eyed treefrog tadpoles (Agalychnis callidryas to cues from a larval dragonfly (Anax amazili. Biomass consumed was manipulated by either increasing the number of prey while holding individual prey size constant, or by holding the number of prey constant and varying individual prey size. We address two questions. (i Do prey reduce growth rate in response to chemical cues in a dose dependent manner? (ii Does the magnitude of the response depend on whether prey consumption increases via number or size of prey? We find that the phenotypic response of prey is an asymptotic function of prey biomass consumed. However, the asymptotic response is higher when more prey are consumed. Our findings have important implications for evaluating past studies and how future experiments should be designed. A stronger response to predation cues generated by more individual prey deaths is consistent with models that predict prey sensitivity to per capita risk, providing a more direct link between empirical and theoretical studies which are often focused on changes in population sizes not individual biomass.

  20. Some types of parent number talk count more than others: relations between parents' input and children's cardinal-number knowledge.

    Science.gov (United States)

    Gunderson, Elizabeth A; Levine, Susan C

    2011-09-01

    Before they enter preschool, children vary greatly in their numerical and mathematical knowledge, and this knowledge predicts their achievement throughout elementary school (e.g. Duncan et al., 2007; Ginsburg & Russell, 1981). Therefore, it is critical that we look to the home environment for parental inputs that may lead to these early variations. Recent work has shown that the amount of number talk that parents engage in with their children is robustly related to a critical aspect of mathematical development - cardinal-number knowledge (e.g. knowing that the word 'three' refers to sets of three entities; Levine, Suriyakham, Rowe, Huttenlocher & Gunderson, 2010). The present study characterizes the different types of number talk that parents produce and investigates which types are most predictive of children's later cardinal-number knowledge. We find that parents' number talk involving counting or labeling sets of present, visible objects is related to children's later cardinal-number knowledge, whereas other types of parent number talk are not. In addition, number talk that refers to large sets of present objects (i.e. sets of size 4 to 10 that fall outside children's ability to track individual objects) is more robustly predictive of children's later cardinal-number knowledge than talk about smaller sets. The relation between parents' number talk about large sets of present objects and children's cardinal-number knowledge remains significant even when controlling for factors such as parents' socioeconomic status and other measures of parents' number and non-number talk. © 2011 Blackwell Publishing Ltd.

  1. Clinical Trials With Large Numbers of Variables: Important Advantages of Canonical Analysis.

    Science.gov (United States)

    Cleophas, Ton J

    2016-01-01

    Canonical analysis assesses the combined effects of a set of predictor variables on a set of outcome variables, but it is little used in clinical trials despite the omnipresence of multiple variables. The aim of this study was to assess the performance of canonical analysis as compared with traditional multivariate methods using multivariate analysis of covariance (MANCOVA). As an example, a simulated data file with 12 gene expression levels and 4 drug efficacy scores was used. The correlation coefficient between the 12 predictor and 4 outcome variables was 0.87 (P = 0.0001) meaning that 76% of the variability in the outcome variables was explained by the 12 covariates. Repeated testing after the removal of 5 unimportant predictor and 1 outcome variable produced virtually the same overall result. The MANCOVA identified identical unimportant variables, but it was unable to provide overall statistics. (1) Canonical analysis is remarkable, because it can handle many more variables than traditional multivariate methods such as MANCOVA can. (2) At the same time, it accounts for the relative importance of the separate variables, their interactions and differences in units. (3) Canonical analysis provides overall statistics of the effects of sets of variables, whereas traditional multivariate methods only provide the statistics of the separate variables. (4) Unlike other methods for combining the effects of multiple variables such as factor analysis/partial least squares, canonical analysis is scientifically entirely rigorous. (5) Limitations include that it is less flexible than factor analysis/partial least squares, because only 2 sets of variables are used and because multiple solutions instead of one is offered. We do hope that this article will stimulate clinical investigators to start using this remarkable method.

  2. Domain General Mediators of the Relation between Kindergarten Number Sense and First-Grade Mathematics Achievement

    Science.gov (United States)

    Hassinger-Das, Brenna; Jordan, Nancy C.; Glutting, Joseph; Irwin, Casey; Dyson, Nancy

    2013-01-01

    Domain general skills that mediate the relation between kindergarten number sense and first-grade mathematics skills were investigated. Participants were 107 children who displayed low number sense in the fall of kindergarten. Controlling for background variables, multiple regression analyses showed that attention problems and executive functioning both were unique predictors of mathematics outcomes. Attention problems were more important for predicting first-grade calculation performance while executive functioning was more important for predicting first-grade performance on applied problems. Moreover, both executive functioning and attention problems were unique partial mediators of the relationship between kindergarten and first-grade mathematics skills. The results provide empirical support for developing interventions that target executive functioning and attention problems in addition to instruction in number skills for kindergartners with initial low number sense. PMID:24237789

  3. Optimization of Approximate Inhibitory Rules Relative to Number of Misclassifications

    KAUST Repository

    Alsolami, Fawaz; Chikalov, Igor; Moshkov, Mikhail; Zielosko, Beata

    2013-01-01

    In this work, we consider so-called nonredundant inhibitory rules, containing an expression “attribute:F value” on the right- hand side, for which the number of misclassifications is at most a threshold γ. We study a dynamic programming approach

  4. Number and importance of somatic cells in goat’s milk

    Directory of Open Access Journals (Sweden)

    Lidija Kozačinski

    2001-04-01

    Full Text Available Goat’s milk samples were examined on mastitis using stable procedure (California-mastitis test. 427 of the examined milk samples (46.82% had positive reaction from 1 to 3 while other 485 samples (53.18% had negative reaction on the mastitis test, indicating that no illness of mammary gland occurred. Number of somatic cells, counted using “Fossomatic” counter, was 1.3x106/ml average. By comparing the results of mastitis-test evaluation (CMT with the number of somatic cells and findings of mastitis agents in milk showed that higher number of somatic cells is not the only indication of goat’s mammary gland illness. Mastitis-test is method that can exclude inflammation of goat’s mammary gland, but every positive reaction should be confirmed or eliminate with bacteriological examination. Based on the results of this research, it has been shown that the limit for somatic cells number in goat's milk can be over 1 000 000/ml.

  5. Carbohydrate-related enzymes of important Phytophthora plant pathogens.

    Science.gov (United States)

    Brouwer, Henk; Coutinho, Pedro M; Henrissat, Bernard; de Vries, Ronald P

    2014-11-01

    Carbohydrate-Active enZymes (CAZymes) form particularly interesting targets to study in plant pathogens. Despite the fact that many CAZymes are pathogenicity factors, oomycete CAZymes have received significantly less attention than effectors in the literature. Here we present an analysis of the CAZymes present in the Phytophthora infestans, Ph. ramorum, Ph. sojae and Pythium ultimum genomes compared to growth of these species on a range of different carbon sources. Growth on these carbon sources indicates that the size of enzyme families involved in degradation of cell-wall related substrates like cellulose, xylan and pectin is not always a good predictor of growth on these substrates. While a capacity to degrade xylan and cellulose exists the products are not fully saccharified and used as a carbon source. The Phytophthora genomes encode larger CAZyme sets when compared to Py. ultimum, and encode putative cutinases, GH12 xyloglucanases and GH10 xylanases that are missing in the Py. ultimum genome. Phytophthora spp. also encode a larger number of enzyme families and genes involved in pectin degradation. No loss or gain of complete enzyme families was found between the Phytophthora genomes, but there are some marked differences in the size of some enzyme families. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. 75 FR 63849 - Proposed Information Collection; OMB Control Number 1018-0078; Injurious Wildlife; Importation...

    Science.gov (United States)

    2010-10-18

    ... provide the fish health data upon which we base our decision to allow importation. We use three forms to... certifying official uses this form to affirm the health status of the fish or their reproductive products to... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R9-FHC-2011-N228; 94100-1311-0000-N5...

  7. Some relations between rank, chromatic number and energy of graphs

    International Nuclear Information System (INIS)

    Akbari, S.; Ghorbani, E.; Zare, S.

    2006-08-01

    The energy of a graph G is defined as the sum of the absolute values of all eigenvalues of G and denoted by E(G). Let G be a graph and rank(G) be the rank of the adjacency matrix of G. In this paper we characterize all the graphs with E(G) = rank(G). Among other results we show that apart from a few families of graphs, E(G) ≥ 2max(χ(G), n - χ(G--bar)), where G-bar and χ(G) are the complement and the chromatic number of G, respectively. Moreover some new lower bounds for E(G) in terms of rank(G) are given. (author)

  8. The importance of plot size and the number of sampling seasons on capturing macrofungal species richness.

    Science.gov (United States)

    Li, Huili; Ostermann, Anne; Karunarathna, Samantha C; Xu, Jianchu; Hyde, Kevin D; Mortimer, Peter E

    2018-07-01

    The species-area relationship is an important factor in the study of species diversity, conservation biology, and landscape ecology. A deeper understanding of this relationship is necessary, in order to provide recommendations on how to improve the quality of data collection on macrofungal diversity in different land use systems in future studies, a systematic assessment of methodological parameters, in particular optimal plot sizes. The species-area relationship of macrofungi in tropical and temperate climatic zones and four different land use systems were investigated by determining the macrofungal species richness in plot sizes ranging from 100 m 2 to 10 000 m 2 over two sampling seasons. We found that the effect of plot size on recorded species richness significantly differed between land use systems with the exception of monoculture systems. For both climate zones, land use system needs to be considered when determining optimal plot size. Using an optimal plot size was more important than temporal replication (over two sampling seasons) in accurately recording species richness. Copyright © 2018 British Mycological Society. Published by Elsevier Ltd. All rights reserved.

  9. Positive approach: Implications for the relation between number theory and geometry, including connection to Santilli mathematics, from Fibonacci reconstitution of natural numbers and of prime numbers

    Energy Technology Data Exchange (ETDEWEB)

    Johansen, Stein E., E-mail: stein.johansen@svt.ntnu.no [Institute for Basic Research, Division of Physics, Palm Harbor, Florida, USA and Norwegian University of Science and Technology, Department of Social Anthropology, Trondheim (Norway)

    2014-12-10

    The paper recapitulates some key elements in previously published results concerning exact and complete reconstitution of the field of natural numbers, both as ordinal and as cardinal numbers, from systematic unfoldment of the Fibonacci algorithm. By this natural numbers emerge as Fibonacci 'atoms' and 'molecules' consistent with the notion of Zeckendorf sums. Here, the sub-set of prime numbers appears not as the primary numbers, but as an epistructure from a deeper Fibonacci constitution, and is thus targeted from a 'positive approach'. In the Fibonacci reconstitution of number theory natural numbers show a double geometrical aspect: partly as extension in space and partly as position in a successive structuring of space. More specifically, the natural numbers are shown to be distributed by a concise 5:3 code structured from the Fibonacci algorithm via Pascal's triangle. The paper discusses possible implications for the more general relation between number theory and geometry, as well as more specifically in relation to hadronic mathematics, initiated by R.M. Santilli, and also briefly to some other recent science linking number theory more directly to geometry and natural systems.

  10. Positive approach: Implications for the relation between number theory and geometry, including connection to Santilli mathematics, from Fibonacci reconstitution of natural numbers and of prime numbers

    International Nuclear Information System (INIS)

    Johansen, Stein E.

    2014-01-01

    The paper recapitulates some key elements in previously published results concerning exact and complete reconstitution of the field of natural numbers, both as ordinal and as cardinal numbers, from systematic unfoldment of the Fibonacci algorithm. By this natural numbers emerge as Fibonacci 'atoms' and 'molecules' consistent with the notion of Zeckendorf sums. Here, the sub-set of prime numbers appears not as the primary numbers, but as an epistructure from a deeper Fibonacci constitution, and is thus targeted from a 'positive approach'. In the Fibonacci reconstitution of number theory natural numbers show a double geometrical aspect: partly as extension in space and partly as position in a successive structuring of space. More specifically, the natural numbers are shown to be distributed by a concise 5:3 code structured from the Fibonacci algorithm via Pascal's triangle. The paper discusses possible implications for the more general relation between number theory and geometry, as well as more specifically in relation to hadronic mathematics, initiated by R.M. Santilli, and also briefly to some other recent science linking number theory more directly to geometry and natural systems

  11. Importance of the effective atomic number (Zeff) of TL materials for radiation dosimetry in clinical applications

    International Nuclear Information System (INIS)

    Gonzalez M, P.R.

    2008-01-01

    The electric power generation, it has been one of the radiation applications of bigger weight, mainly in developed countries. Another sector of more impact is without a doubt that of the medicine. However, for a sure operation with radiations, those international organisms of radiological safety, exist every time more precise detection systems. The thermoluminescent dosimetry is one of the more reliable methods for this purpose, for that several groups of investigators from different parts of the world, they have guided its investigations in the development of new TL materials. However, to avoid underestimate or overestimation of the measured dose with the use of these materials, it should take into account it effective atomic number (Z eff ) it is well known that some TL materials considered as equivalent to the tissue, presents smaller TL intensity when being irradiated with low energy photons, while the TL material known as not equivalent to the tissue, they present the supra sensitivity effect for this radiation type. Nowadays, the estimate of the Z eff has not been clear, in this work the Z eff is determined by means of the traditional methods and an own method is presented for its determination. The results of the TL signal of different materials, when being irradiated with photons of effective energy between 24 keV and 1.25 MeV and their relationship with their calculated Z eff are also presented. (Author)

  12. The importance of mammography in relationship to the number of treated carcinomas of the breast

    International Nuclear Information System (INIS)

    Paterok, E.M.; Weishaar, J.; Bischoff, J.; Mueller, D.

    1980-01-01

    From 1976 to 1978 11,197 women were examined clinically and mammographically. Biopsy material from 1,673 breasts were examined microscopically. In 536 cases, or almost every third case a carcinoma of the breast was detected. The cancer was bilateral in 19 cases and the total number of women was therefore 517. A clinically occult tumour was only found in 7.7% of the cases. 5% of these patients were high risk patients and 2.7% preventive examinations. 5 women with occult carcinoma of the breast were under age 40 and 14 under age 50. Benign changes of the glandular tissue were found in 59.5% of the cases. Marked proliferative changes were found in 4.6% of the cases and carcinoma in situ was found in 3.8% of the patients. In the age group 45-54 benign and malignant findings was 1:1 in the age group 55-59 and was less than 1:2 in the age group over 70. A sophistication of the mammographic technique must be obtained. A thorough microscopic examination of tissue from subcutaneous mastectomies and tissue obtained at the time of reduction mammoplasties showed occasionally unexpected malignant tissue in an unexpected location. Expecially these cases are suitable for later comparison to the mammographies. (orig./MG) [de

  13. The covariance between the number of accidents and the number of victims in multivariate analysis of accident related outcomes

    NARCIS (Netherlands)

    Bijleveld, F. D.

    In this study some statistical issues involved in the simultaneous analysis of accident related outcomes of the road traffic process are investigated. Since accident related outcomes like the number of victims, fatalities or accidents show interdependencies, their simultaneous analysis requires that

  14. The Prime Numbers Hidden Symmetric Structure and its Relation to the Twin Prime Infinitude and an Improved Prime Number Theorem

    CERN Document Server

    Mikoss, I

    2006-01-01

    Due to the sieving process represented by a Secondary Sieving Map; during the generation of the prime numbers, geometric structures with definite symmetries are formed which become evident through their geometrical representations. The study of these structures allows the development of a constructive prime generating formula. This defines a mean prime density yielding a second order recursive and discrete prime producing formula and a second order differential equation whose solutions produce an improved Prime Number Theorem. Applying these results to twin prime pairs is possible to generate a Twin Prime Number Theorem and important conclusions about the infinitude of the twin primes.

  15. The importance of health-related physical fitness

    Directory of Open Access Journals (Sweden)

    Maria Fátima Glaner

    2003-12-01

    Full Text Available Mechanization and automation, swift communication and transport, computer usage and television viewing have reduced the need for vigorous occupations and discouraged involvement in leisure-time recreational activity. Studies have reported that there is a causal relationship between the risk of chronic disease incidence and mortality and physical activity and/or physical fi tness. Therefore, the aim of this review is to summarize and synthesize the association between health-related physical fi tness (aerobic endurance, fl exibility, strength/ endurance, body fat and chronic diseases. The papers reviewed demonstrate that higher and moderate levels of aerobic endurance, fl exibility, muscular strength/endurance, and desirable body fat levels, are very important for promoting health at all ages, and to avoid early development of chronic diseases. RESUMO A mecanização e a automação, o transporte e a comunicação rápidos, o uso do computador e da televisão têm diminuído atividades vigorosas, inclusive no tempo livre. Estudos reportam que a relação entre o risco de incidência de doenças crônico-degenerativas e a atividade física e/ou a aptidão física é causal. Portanto, o objetivo desta revisão é resumir e sintetizar a associação entre aptidão física relacionada à saúde (aptidão cardiorrespiratória, fl exibilidade, força/resistência muscular e gordura corporal e as doenças crônicodegenerativas. Os estudos mostram que altos e moderados níveis de aptidão cardiorrespiratória, fl exibilidade, força/resistência muscular, e um nível adequado de gordura são muito importantes para promover a saúde em todas idades, bem como evitar o desenvolvimento precoce de doenças crônico-degenerativas.

  16. Measuring the relative importance of strategic thinking dimensions in relation to counterproductive behavior

    Directory of Open Access Journals (Sweden)

    Afsaneh Zamani Moghaddam

    2013-11-01

    Full Text Available The purpose of this paper is to explore the relative importance of strategic thinking dimensions in prediction of counter-productive behavior. The research method is based on a descriptive- Survey research. After collecting the questionnaires from 73 top managers and 110 staffs, the correlations between strategic thinking dimensions and counterproductive behavior were calculated. The relative importance method was used to calculate the relative weight of each dimension of strategic thinking in prediction of counterproductive behaviors. The results show that the strategic thinking of top managers is associated with their counterproductive behavior (correlation coefficient -0.38. Furthermore, The results of the Relative Importance Method indicate that the relative importance of each dimension of strategic thinking in prediction of counterproductive behavior is not the same. System perspective with 31.1% has the highest importance and hypothesis driven with 11.7% has the lowest weight. Intent focus, thinking in time and intelligent opportunism predict 14.1%, 13.3%, and 29.8% of counter-productive changes, respectively.

  17. Yield in almond is related more to the abundance of flowers than the relative number of flowers that set fruit

    Directory of Open Access Journals (Sweden)

    Sergio Tombesi

    2016-11-01

    Full Text Available Almond tree yield is a function of the number of flowers on a tree and the percentage of flowers that set fruit. Almonds are borne on spurs (short proleptic shoots that can have both leaves and flowers. Almond tree spur dynamics research has documented that previous year spur leaf area is a predictive parameter for year-to-year spur survival, spur flowering and to a lesser extent spur fruiting, while previous year fruit bearing has a negative impact on subsequent year flowering. However, a question remained about whether yields are more dependent on flower numbers or relative fruit set of the flowers that are present. The aim of the present work was to compare the importance of flower abundance with that of relative fruit set in determining the productivity of a population of tagged spurs in almond trees over a 6-year period. Overall tree yield among years was more sensitive to total number of flowers on a tree rather than relative fruit set. These results emphasize the importance of maintaining large populations of healthy flowering spurs for sustained high production in almond orchards.

  18. Elevate or Relegate? The Relative Importance of Mathematics

    Science.gov (United States)

    Huckstep, Peter

    2007-01-01

    The value of any subject on a crowded, contested and compulsory curriculum is, or at least should be, open to debate. More importantly, when different subjects are prioritized over others, the justification for the ranking of such subjects should also be submitted to sustained enquiry. Mathematics enjoys a prestigious place in the English National…

  19. Introduction: The Growing Importance of Traditional Forest-Related Knowledge

    Science.gov (United States)

    Ronald L. Trosper; John A. Parrotta

    2012-01-01

    The knowledge, innovations, and practices of local and indigenous communities have supported their forest-based livelihoods for countless generations. The role of traditional knowledge—and the bio-cultural diversity it sustains—is increasingly recognized as important by decision makers, conservation and development organizations, and the scientifi c community. However...

  20. The Relative Importance of the Channels of Monetary Policy ...

    African Journals Online (AJOL)

    importance channels of monetary policy which are working in Zambia. It answers the ... several ways through which monetary policy affect the balance sheets of economic agents and hence ... economies, especially those with flexible exchange rate regimes. ..... transmission channels work endogenously or exogenously.

  1. Relative Importance of Professional Practice and Engineering Management Competencies

    Science.gov (United States)

    Pons, Dirk

    2016-01-01

    Problem: The professional practice of engineering always involves engineering management, but it is difficult to know what specifically to include in the undergraduate curriculum. Approach: The population of New Zealand practising engineers was surveyed to determine the importance they placed on specific professional practice and engineering…

  2. Relative importance of professional practice and engineering management competencies

    Science.gov (United States)

    Pons, Dirk

    2016-09-01

    Problem: The professional practice of engineering always involves engineering management, but it is difficult to know what specifically to include in the undergraduate curriculum. Approach: The population of New Zealand practising engineers was surveyed to determine the importance they placed on specific professional practice and engineering management competencies. Findings: Results show that communication and project planning were the two most important topics, followed by others as identified. The context in which practitioners use communication skills was found to be primarily with project management, with secondary contexts identified. The necessity for engineers to develop the ability to use multiple soft skills in an integrative manner is strongly supported by the data. Originality: This paper is one of only a few large-scale surveys of practising engineers to have explored the soft skill attributes. It makes a didactic contribution of providing a ranked list of topics which can be used for designing the curriculum and prioritising teaching effort, which has not previously been achieved. It yields the new insight that combinations of topics are sometimes more important than individual topics.

  3. The relative importance of climatic gradient versus human ...

    African Journals Online (AJOL)

    The study aimed to investigate the relative significance of effects of climatic variability and human disturbance on the population structure of the threatened species Afzelia africana Sm. ex Pers. in the Republic of Benin in West Africa. Forest inventory data such as regeneration density, tree diameter and total height were ...

  4. Helping Students Assess the Relative Importance of Different Intermolecular Interactions

    Science.gov (United States)

    Jasien, Paul G.

    2008-01-01

    A semi-quantitative model has been developed to estimate the relative effects of dispersion, dipole-dipole interactions, and H-bonding on the normal boiling points ("T[subscript b]") for a subset of simple organic systems. The model is based upon a statistical analysis using multiple linear regression on a series of straight-chain organic…

  5. Travel-related leptospirosis: a series of 15 imported cases.

    Science.gov (United States)

    van de Werve, Charlotte; Perignon, Alice; Jauréguiberry, Stéphane; Bricaire, François; Bourhy, Pascal; Caumes, Eric

    2013-01-01

    Leptospirosis belongs to the spectrum of travel-related infections. We retrospectively studied all the consecutive cases of travel-related leptospirosis seen in our department between January 2008 and September 2011. Patients were included with a clinical picture compatible with the disease within 21 days after return, the presence of a thermoresistant antigen or IgM antibodies, Elisa ≥ 1 /400, and a positive microagglutination test (MAT) ≥ 1/100. Fifteen leptospirosis cases were evaluated. Exposure occurred in Asia (47%), Africa (20%), the Caribbean (20%), and Indian Ocean (13%). Fourteen patients were infected during water-related activities. On admission the most frequent symptoms were fever (100%), headache (80%), and digestive disorders (67%). Relevant laboratory findings included impaired liver function tests (100%), lymphocytopenia (80%), thrombocytopenia (67%), and elevated C-reactive protein (CRP) (67%). Our cases were confirmed by MAT that found antibodies against nine different serovars. Seven patients were cured with amoxicillin, four with doxycycline, two with ceftriaxone, one with ceftriaxone, doxycycline, and spiramycin, whereas one recovered spontaneously (retrospective diagnosis). Eight patients were hospitalized. All patients recovered. Our cases involved nine different serovars. They were related to travel in Asia, Africa, and the Caribbean. Bathing or other fresh-water leisure activities (canoeing, kayaking, rafting) are the most likely at-risk exposure. Any traveler with fever and at-risk exposure should be investigated for leptospirosis. © 2013 International Society of Travel Medicine.

  6. The relative importance of relational and scientific characteristics of psychotherapy: Perceptions of community members vs. therapists.

    Science.gov (United States)

    Farrell, Nicholas R; Deacon, Brett J

    2016-03-01

    Although client preferences are an integral component of evidence-based practice in psychology (American Psychological Association, 2006), relatively little research has examined what potential mental health consumers value in the psychotherapy they may receive. The present study was conducted to examine community members' preferences for the scientific and relational aspects of psychotherapy for different types of presenting problems, and how accurately therapists perceive these preferences. Community members (n = 200) were surveyed about the importance of scientific (e.g., demonstrated efficacy in clinical trials) and relational (e.g., therapist empathy) characteristics of psychotherapy both for anxiety disorders (e.g., obsessive-compulsive disorder) and disorder-nonspecific issues (e.g., relationship difficulties). Therapists (n = 199) completed the same survey and responded how they expected the average mental health consumer would. Results showed that although community members valued relational characteristics significantly more than scientific characteristics, the gap between these two was large for disorder-nonspecific issues (d = 1.24) but small for anxiety disorders (d = .27). Community members rated scientific credibility as important across problem types. Therapists significantly underestimated the importance of scientific characteristics to community members, particularly in the treatment of disorder-nonspecific issues (d = .74). Therapists who valued research less in their own practice were more likely to underestimate the importance of scientific credibility to community members. The implications of the present findings for understanding the nature of client preferences in evidence-based psychological practice are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Student emotions in class : The relative importance of teachers and their interpersonal relations with students

    NARCIS (Netherlands)

    Mainhard, M.T.; Oudman, V.S.; Hornstra, T.E.; Bosker, R.J.; T., Goetz

    2018-01-01

    This study highlights the importance of teachers in relation to the emotions students experience in class. First, in line with the work of Kenny, we argue that the specific relationship that evolves between teachers and students drives students' emotional experiences. We decompose variability in

  8. Number-Phase Wigner Representation and Entropic Uncertainty Relations for Binomial and Negative Binomial States

    International Nuclear Information System (INIS)

    Amitabh, J.; Vaccaro, J.A.; Hill, K.E.

    1998-01-01

    We study the recently defined number-phase Wigner function S NP (n,θ) for a single-mode field considered to be in binomial and negative binomial states. These states interpolate between Fock and coherent states and coherent and quasi thermal states, respectively, and thus provide a set of states with properties ranging from uncertain phase and sharp photon number to sharp phase and uncertain photon number. The distribution function S NP (n,θ) gives a graphical representation of the complimentary nature of the number and phase properties of these states. We highlight important differences between Wigner's quasi probability function, which is associated with the position and momentum observables, and S NP (n,θ), which is associated directly with the photon number and phase observables. We also discuss the number-phase entropic uncertainty relation for the binomial and negative binomial states and we show that negative binomial states give a lower phase entropy than states which minimize the phase variance

  9. The relative importance of service dimensions in a healthcare setting.

    Science.gov (United States)

    Ramsaran-Fowdar, Rooma Roshnee

    2008-01-01

    The paper aims to focus on an augmented SERVQUAL instrument that was used to measure private patients' service expectations and perceptions. A questionnaire was administered to 750 and 34 per cent responded. A new service quality instrument called PRIVHEALTHQUAL emerged from the study, based on factor and reliability analysis. The "reliability and fair and equitable treatment" factor was found to be the most important healthcare service quality dimension. Adds to the existing body of research on service quality and demonstrates that SERVQUAL is not a generic service quality measure for all industries.

  10. The importance of relations and rationality in ethnography

    DEFF Research Database (Denmark)

    Kjær, Malene

    I claim that it is hard to understand the cooperation and also the distance that there is between the ethnographic field and the researcher when we are involved in ethnographic data collection. From the classical scholarly point of view, in an observation situation we can either be participatory...... place. I see nexus analysis as a methodology that can solve this dilemma. With nexus analysis, the researcher uses a fair amount of time to understand the people, their routines, work conditions, etc. in the field in question. Also, it is equally relevant for the researcher to get to know the concrete...... locations and places with their specific work practices. This is why the first and important step in nexus analysis is to “engage” in the practices that constitute the ethnographic field under analysis. This means in practice that the researcher will familiarize oneself with the field without becoming part...

  11. The importance of context: When relative relief renders pain pleasant

    Science.gov (United States)

    Leknes, Siri; Berna, Chantal; Lee, Michael C.; Snyder, Gregory D.; Biele, Guido; Tracey, Irene

    2013-01-01

    Context can influence the experience of any event. For instance, the thought that “it could be worse” can improve feelings towards a present misfortune. In this study we measured hedonic feelings, skin conductance, and brain activation patterns in 16 healthy volunteers who experienced moderate pain in two different contexts. In the “relative relief context,” moderate pain represented the best outcome, since the alternative outcome was intense pain. However, in the control context, moderate pain represented the worst outcome and elicited negative hedonic feelings. The context manipulation resulted in a “hedonic flip,” such that moderate pain elicited positive hedonics in the relative relief context. Somewhat surprisingly, moderate pain was even rated as pleasant in this context, despite being reported as painful in the control context. This “hedonic flip” was corroborated by physiological and functional neuroimaging data. When moderate pain was perceived as pleasant, skin conductance and activity in insula and dorsal anterior cingulate were significantly attenuated relative to the control moderate stimulus. “Pleasant pain” also increased activity in reward and valuation circuitry, including the medial orbitofrontal and ventromedial prefrontal cortices. Furthermore, the change in outcome hedonics correlated with activity in the periacqueductal grey (PAG) of the descending pain modulatory system (DPMS). The context manipulation also significantly increased functional connectivity between reward circuitry and the PAG, consistent with a functional change of the DPMS due to the altered motivational state. The findings of this study point to a role for brainstem and reward circuitry in a context-induced “hedonic flip” of pain. PMID:23352758

  12. The importance planning of public relations in tourist organizations’ communication

    Directory of Open Access Journals (Sweden)

    Maria Carmenl IORDACHE

    2009-12-01

    Full Text Available Accomplishing efficient communication on tourist markets means efficiently developing and operating a communication system, that is designing and implementing an adequate structure of communication activities. Tourist organizations must have a communication strategy according to communication activities’ target, global objectives pursued, communication targets aimed, communication media used and contents of transmitted messages and, last but not least, resources allocated to implement communicational procedures. In order to attract consumers on a highly competitive market, there are several management-marketing instruments of which some are public relations whose role is to create a positive image of a tourist organization and, implicitly, of its products and services.

  13. How Do Different Aspects of Spatial Skills Relate to Early Arithmetic and Number Line Estimation?

    Directory of Open Access Journals (Sweden)

    Véronique Cornu

    2017-12-01

    Full Text Available The present study investigated the predictive role of spatial skills for arithmetic and number line estimation in kindergarten children (N = 125. Spatial skills are known to be related to mathematical development, but due to the construct’s non-unitary nature, different aspects of spatial skills need to be differentiated. In the present study, a spatial orientation task, a spatial visualization task and visuo-motor integration task were administered to assess three different aspects of spatial skills. Furthermore, we assessed counting abilities, knowledge of Arabic numerals, quantitative knowledge, as well as verbal working memory and verbal intelligence in kindergarten. Four months later, the same children performed an arithmetic and a number line estimation task to evaluate how the abilities measured at Time 1 predicted early mathematics outcomes. Hierarchical regression analysis revealed that children’s performance in arithmetic was predicted by their performance on the spatial orientation and visuo-motor integration task, as well as their knowledge of the Arabic numerals. Performance in number line estimation was significantly predicted by the children’s spatial orientation performance. Our findings emphasize the role of spatial skills, notably spatial orientation, in mathematical development. The relation between spatial orientation and arithmetic was partially mediated by the number line estimation task. Our results further show that some aspects of spatial skills might be more predictive of mathematical development than others, underlining the importance to differentiate within the construct of spatial skills when it comes to understanding numerical development.

  14. The approximate number system and its relation to early math achievement: evidence from the preschool years.

    Science.gov (United States)

    Bonny, Justin W; Lourenco, Stella F

    2013-03-01

    Humans rely on two main systems of quantification; one is nonsymbolic and involves approximate number representations (known as the approximate number system or ANS), and the other is symbolic and allows for exact calculations of number. Despite the pervasiveness of the ANS across development, recent studies with adolescents and school-aged children point to individual differences in the precision of these representations that, importantly, have been shown to relate to symbolic math competence even after controlling for general aspects of intelligence. Such findings suggest that the ANS, which humans share with nonhuman animals, interfaces specifically with a uniquely human system of formal mathematics. Other findings, however, point to a less straightforward picture, leaving open questions about the nature and ontogenetic origins of the relation between these two systems. Testing children across the preschool period, we found that ANS precision correlated with early math achievement but, critically, that this relation was nonlinear. More specifically, the correlation between ANS precision and math competence was stronger for children with lower math scores than for children with higher math scores. Taken together, our findings suggest that early-developing connections between the ANS and mathematics may be fundamentally discontinuous. Possible mechanisms underlying such nonlinearity are discussed. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Bank Control and the Number of Bank Relations of Japanese Firms

    NARCIS (Netherlands)

    Sterken, Elmer; Ogawa, Kazuo; Tokutsu, Ichiro

    2005-01-01

    We explore the determinants of the number of long-term bank relations of listed Japanese firms using a unique data set covering the period 1982-1999. Having a relation with a top-equity holding bank reduces the number of bank relations, while debt-rich and cash-poor firms have more bank relations.

  16. Calculation of the number of branches of multi-valued decision trees in computer aided importance rank of parameters

    Directory of Open Access Journals (Sweden)

    Tiszbierek Agnieszka

    2017-01-01

    Full Text Available An elaborated digital computer programme supporting the time-consuming process of selecting the importance rank of construction and operation parameters by means of stating optimum sets is based on the Quine – McCluskey algorithm of minimizing individual partial multi-valued logic functions. The example with real time data, calculated by means of the programme, showed that among the obtained optimum sets there were such which had a different number of real branches after being presented on the multi-valued logic decision tree. That is why an idea of elaborating another functionality of the programme – a module calculating the number of branches of real, multi-valued logic decision trees presenting optimum sets chosen by the programme was pursued. This paper presents the idea and the method for developing a module calculating the number of branches, real for each of optimum sets indicated by the programme, as well as to the calculation process.

  17. Number of endemic and native plant species in the Galapagos Archipelago in relation to geographical parameters

    DEFF Research Database (Denmark)

    Willerslev, Eske; Hansen, Anders J.; Nielsen, Kirstine Klitgaard

    2002-01-01

    By simple and multiple regression analyses we investigate updated species numbers of endemic and native vascular plants and seed plants in the Galapagos Archipelago in relation to geographical parameters. We find that the best models to describe species numbers are regression models with log......-transformed species numbers as dependent and log-transformed modified area (i.e. area not covered with barren lava) as an independent variable. This holds both for total species number, for native species number, for endemic species number and for total number of seed plants as well as number of endemic seed plants...

  18. Recurrence Relations and Generating Functions of the Sequence of Sums of Corresponding Factorials and Triangular Numbers

    Directory of Open Access Journals (Sweden)

    Romer C. Castillo

    2015-11-01

    Full Text Available This study established some recurrence relations and exponential generating functions of the sequence of factoriangular numbers. A factoriangular number is defined as a sum of corresponding factorial and triangular number. The proofs utilize algebraic manipulations with some known results from calculus, particularly on power series and Maclaurin’s series. The recurrence relations were found by manipulating the formula defining a factoringular number while the ascertained exponential generating functions were in the closed form.

  19. Mass and number size distributions of emitted particulates at five important operation units in a hazardous industrial waste incineration plant.

    Science.gov (United States)

    Lin, Chi-Chi; Huang, Hsiao-Lin; Hsiao, Wen-Yuan

    2016-01-01

    Past studies indicated particulates generated by waste incineration contain various hazardous compounds. The aerosol characteristics are very important for particulate hazard control and workers' protection. This study explores the detailed characteristics of emitted particulates from each important operation unit in a rotary kiln-based hazardous industrial waste incineration plant. A dust size analyzer (Grimm 1.109) and a scanning mobility particle sizer (SMPS) were used to measure the aerosol mass concentration, mass size distribution, and number size distribution at five operation units (S1-S5) during periods of normal operation, furnace shutdown, and annual maintenance. The place with the highest measured PM10 concentration was located at the area of fly ash discharge from air pollution control equipment (S5) during the period of normal operation. Fine particles (PM2.5) constituted the majority of the emitted particles from the incineration plant. The mass size distributions (elucidated) made it clear that the size of aerosols caused by the increased particulate mass, resulting from work activities, were mostly greater than 1.5 μm. Whereas the number size distributions showed that the major diameters of particulates that caused the increase of particulate number concentrations, from work activities, were distributed in the sub micrometer range. The process of discharging fly ash from air pollution control equipment can significantly increase the emission of nanoparticles. The mass concentrations and size distributions of emitted particulates were different at each operation unit. This information is valuable for managers to take appropriate strategy to reduce the particulate emission and associated worker exposure.

  20. 77 FR 65702 - Agency Information Collection Activities: Refugee/Asylee Relative Petition, Form Number I-730...

    Science.gov (United States)

    2012-10-30

    ...-0037] Agency Information Collection Activities: Refugee/Asylee Relative Petition, Form Number I-730... request. (2) Title of the Form/Collection: Refugee/Asylee Relative Petition. (3) Agency form number, if... households. Form I- 730 will be used by an asylee or refugee to file on behalf of his or her spouse and/or...

  1. From rational numbers to algebra: separable contributions of decimal magnitude and relational understanding of fractions.

    Science.gov (United States)

    DeWolf, Melissa; Bassok, Miriam; Holyoak, Keith J

    2015-05-01

    To understand the development of mathematical cognition and to improve instructional practices, it is critical to identify early predictors of difficulty in learning complex mathematical topics such as algebra. Recent work has shown that performance with fractions on a number line estimation task predicts algebra performance, whereas performance with whole numbers on similar estimation tasks does not. We sought to distinguish more specific precursors to algebra by measuring multiple aspects of knowledge about rational numbers. Because fractions are the first numbers that are relational expressions to which students are exposed, we investigated how understanding the relational bipartite format (a/b) of fractions might connect to later algebra performance. We presented middle school students with a battery of tests designed to measure relational understanding of fractions, procedural knowledge of fractions, and placement of fractions, decimals, and whole numbers onto number lines as well as algebra performance. Multiple regression analyses revealed that the best predictors of algebra performance were measures of relational fraction knowledge and ability to place decimals (not fractions or whole numbers) onto number lines. These findings suggest that at least two specific components of knowledge about rational numbers--relational understanding (best captured by fractions) and grasp of unidimensional magnitude (best captured by decimals)--can be linked to early success with algebraic expressions. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Sequential optimization of approximate inhibitory rules relative to the length, coverage and number of misclassifications

    KAUST Repository

    Alsolami, Fawaz; Chikalov, Igor; Moshkov, Mikhail

    2013-01-01

    This paper is devoted to the study of algorithms for sequential optimization of approximate inhibitory rules relative to the length, coverage and number of misclassifications. Theses algorithms are based on extensions of dynamic programming approach

  3. Navigating the complexities of qualitative comparative analysis: case numbers, necessity relations, and model ambiguities.

    Science.gov (United States)

    Thiem, Alrik

    2014-12-01

    In recent years, the method of Qualitative Comparative Analysis (QCA) has been enjoying increasing levels of popularity in evaluation and directly neighboring fields. Its holistic approach to causal data analysis resonates with researchers whose theories posit complex conjunctions of conditions and events. However, due to QCA's relative immaturity, some of its technicalities and objectives have not yet been well understood. In this article, I seek to raise awareness of six pitfalls of employing QCA with regard to the following three central aspects: case numbers, necessity relations, and model ambiguities. Most importantly, I argue that case numbers are irrelevant to the methodological choice of QCA or any of its variants, that necessity is not as simple a concept as it has been suggested by many methodologists, and that doubt must be cast on the determinacy of virtually all results presented in past QCA research. By means of empirical examples from published articles, I explain the background of these pitfalls and introduce appropriate procedures, partly with reference to current software, that help avoid them. QCA carries great potential for scholars in evaluation and directly neighboring areas interested in the analysis of complex dependencies in configurational data. If users beware of the pitfalls introduced in this article, and if they avoid mechanistic adherence to doubtful "standards of good practice" at this stage of development, then research with QCA will gain in quality, as a result of which a more solid foundation for cumulative knowledge generation and well-informed policy decisions will also be created. © The Author(s) 2014.

  4. Domain-general mediators of the relation between kindergarten number sense and first-grade mathematics achievement.

    Science.gov (United States)

    Hassinger-Das, Brenna; Jordan, Nancy C; Glutting, Joseph; Irwin, Casey; Dyson, Nancy

    2014-02-01

    Domain-general skills that mediate the relation between kindergarten number sense and first-grade mathematics skills were investigated. Participants were 107 children who displayed low number sense in the fall of kindergarten. Controlling for background variables, multiple regression analyses showed that both attention problems and executive functioning were unique predictors of mathematics outcomes. Attention problems were more important for predicting first-grade calculation performance, whereas executive functioning was more important for predicting first-grade performance on applied problems. Moreover, both executive functioning and attention problems were unique partial mediators of the relationship between kindergarten and first-grade mathematics skills. The results provide empirical support for developing interventions that target executive functioning and attention problems in addition to instruction in number skills for kindergartners with initial low number sense. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. On Sequences of Numbers and Polynomials Defined by Linear Recurrence Relations of Order 2

    Directory of Open Access Journals (Sweden)

    Tian-Xiao He

    2009-01-01

    Full Text Available Here we present a new method to construct the explicit formula of a sequence of numbers and polynomials generated by a linear recurrence relation of order 2. The applications of the method to the Fibonacci and Lucas numbers, Chebyshev polynomials, the generalized Gegenbauer-Humbert polynomials are also discussed. The derived idea provides a general method to construct identities of number or polynomial sequences defined by linear recurrence relations. The applications using the method to solve some algebraic and ordinary differential equations are presented.

  6. Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis.

    Science.gov (United States)

    Kenins, Linda; Gill, Jason W; Holländer, Georg A; Wodnar-Filipowicz, Aleksandra

    2010-01-01

    T-cell production throughout life depends on efficient colonization and intrathymic expansion of BM-derived hematopoietic precursors. After irradiation-induced thymic damage, thymic recovery is facilitated by Flt3 ligand (FL), expressed by perivascular fibroblasts surrounding the thymic entry site of Flt3 receptor-positive progenitor cells. Whether intrathymic FL-Flt3 interactions play a role in steady-state replenishment of T cells remains unknown. Here, using competitive BM transplantation studies and fetal thymic organ cultures we demonstrated the continued numerical advantage of Flt3+ intrathymic T-cell precursors. Sub-kidney capsule thymic transplantation experiments, in which WT and FL-/- thymic lobes were grafted into FL-/- recipients, revealed that FL expression by the thymic microenvironment plays a role in steady-state thymopoiesis. The deficiency of the most immature thymic T-cell precursors correlated to upregulation of FL by thymic MTS15+ fibroblasts, suggesting that the number of Flt3+ progenitor cells may regulate the thymic expression of this cytokine. Together, these results show that FL expression by thymic stromal fibroblasts interacting with Flt3+ T-cell progenitors is important for the physiological maintenance of early T-cell development.

  7. Conceptualisation of ageing in relation to factors of importance for extending working life - a review.

    Science.gov (United States)

    Nilsson, Kerstin

    2016-07-01

    The aim of this study was to explore and understand the complexity of ageing in relation to factors of importance for extending working life. Discourse analysis of documents was used in an integrative review including 128 articles. Four different conceptualisation of ageing are shown to affect older workers' ability to extend their working life: (a) biological ageing people's health in relation to their physical and mental work environment, their pace of work and recuperation needs; (b) chronological ageing statutory retirement age and policies and economic incentives devised for older workers by society, unions and organisations/enterprises; (c) social ageing inclusion in different social groups, the attitude of managers, organisations and family members, the leisure activities and surrounding environment; and (d) mental/cognitive ageing self-crediting, motivating and meaningful activities, competence and skills in working life. CONCLUSIONS SOCIETIES TODAY FOCUS MOSTLY ON CHRONOLOGICAL AGEING AND ARE LOOKING TO INCREASE THE RETIREMENT AGE WITH REGARD TO STATUTORY PENSION SYSTEMS, EG BEYOND 65 YEARS OF AGE THE INTER-RELATIONSHIPS BETWEEN CHRONOLOGICAL, MENTAL, BIOLOGICAL AND SOCIAL AGEING AND THE NINE AREAS IDENTIFIED AS BEING IMPORTANT TO OLDER WORKERS IN THESE RESPECTS NEED TO BE CONSIDERED WHEN AIMING TO PROVIDE A SUSTAINABLE WORKING LIFE FOR THE INCREASING NUMBERS OF OLDER WORKERS IN MODERN SOCIETY THE THEORETICAL MODEL DEVELOPED IS A CONTRIBUTION TO THE CRITICAL DEBATE THAT CAN BE APPLIED BY SOCIETIES, EMPLOYERS AND MANAGERS IN ORDER TO PROVIDE OLDER WORKERS WITH AN INCLUSIVE AND SUSTAINABLE EXTENDED WORKING LIFE. © 2016 the Nordic Societies of Public Health.

  8. Effects of relative thickness on aerodynamic characteristics of airfoil at a low Reynolds number

    Directory of Open Access Journals (Sweden)

    Ma Dongli

    2015-08-01

    Full Text Available This study focuses on the characteristics of low Reynolds number flow around airfoil of high-altitude unmanned aerial vehicles (HAUAVs cruising at low speed. Numerical simulation on the flows around several representative airfoils is carried out to investigate the low Reynolds number flow. The water tunnel model tests further validate the accuracy and effectiveness of the numerical method. Then the effects of the relative thickness of airfoil on aerodynamic performance are explored, using the above numerical method, by simulating flows around airfoils of different relative thicknesses (12%, 14%, 16%, 18%, as well as different locations of the maximum relative thickness (x/c = 22%, 26%, 30%, 34%, at a low Reynolds number of 5 × 105. Results show that performance of airfoils at low Reynolds number is mainly affected by the laminar separation bubble. On the premise of good stall characteristics, the value of maximum relative thickness should be as small as possible, and the location of the maximum relative thickness ought to be closer to the trailing edge to obtain fine airfoil performance. The numerical method is feasible for the simulation of low Reynolds number flow. The study can help to provide a basis for the design of low Reynolds number airfoil.

  9. Amphibian and reptile communities in eleven Sites of Community Importance (SCI: relations between SCI area, heterogeneity and richness

    Directory of Open Access Journals (Sweden)

    Luca Canova

    2007-11-01

    Full Text Available Seven species of amphibians and reptiles were observed in eleven Sites of Community Importance (SCI of the Lodi Province (NW Italy. Distribution and relative abundance of amphibians appeared more variable than reptiles. Some species of conservation concern as R. latastei were influenced by habitat physiognomy, i.e. the surface of wooded areas are important in predict presence and relative abundance of this species. SCI with wider surfaces and higher habitat heterogeneity included higher number of species. Species richness, here considered as a raw index of biodiversity value and community quality, was significantly related to SCI area and habitat heterogeneity; since this significant positive relation is confirmed both for amphibians and reptiles we suggest that, in planning of natural areas, priority must be retained for biotopes able to host the higher number of species.

  10. QTL Mapping of Kernel Number-Related Traits and Validation of One Major QTL for Ear Length in Maize.

    Science.gov (United States)

    Huo, Dongao; Ning, Qiang; Shen, Xiaomeng; Liu, Lei; Zhang, Zuxin

    2016-01-01

    The kernel number is a grain yield component and an important maize breeding goal. Ear length, kernel number per row and ear row number are highly correlated with the kernel number per ear, which eventually determines the ear weight and grain yield. In this study, two sets of F2:3 families developed from two bi-parental crosses sharing one inbred line were used to identify quantitative trait loci (QTL) for four kernel number-related traits: ear length, kernel number per row, ear row number and ear weight. A total of 39 QTLs for the four traits were identified in the two populations. The phenotypic variance explained by a single QTL ranged from 0.4% to 29.5%. Additionally, 14 overlapping QTLs formed 5 QTL clusters on chromosomes 1, 4, 5, 7, and 10. Intriguingly, six QTLs for ear length and kernel number per row overlapped in a region on chromosome 1. This region was designated qEL1.10 and was validated as being simultaneously responsible for ear length, kernel number per row and ear weight in a near isogenic line-derived population, suggesting that qEL1.10 was a pleiotropic QTL with large effects. Furthermore, the performance of hybrids generated by crossing 6 elite inbred lines with two near isogenic lines at qEL1.10 showed the breeding value of qEL1.10 for the improvement of the kernel number and grain yield of maize hybrids. This study provides a basis for further fine mapping, molecular marker-aided breeding and functional studies of kernel number-related traits in maize.

  11. Kindergartners' Spontaneous Focusing on Numerosity in Relation to Their Number-Related Utterances during Numerical Picture Book Reading

    Science.gov (United States)

    Rathé, Sanne; Torbeyns, Joke; Hannula-Sormunen, Minna M.; Verschaffel, Lieven

    2016-01-01

    This study investigated the relationship between kindergartners' Spontaneous Focusing on Numerosity (SFON) and their number-related utterances during numerical picture book reading. Forty-eight 4- to 5-year-olds were individually interviewed via a SFON Imitation Task and a numerical picture book reading activity. We expected differences in the…

  12. Unpacking symbolic number comparison and its relation with arithmetic in adults.

    Science.gov (United States)

    Sasanguie, Delphine; Lyons, Ian M; De Smedt, Bert; Reynvoet, Bert

    2017-08-01

    Symbolic number - or digit - comparison has been a central tool in the domain of numerical cognition for decades. More recently, individual differences in performance on this task have been shown to robustly relate to individual differences in more complex math processing - a result that has been replicated across many different age groups. In this study, we 'unpack' the underlying components of digit comparison (i.e. digit identification, digit to number-word matching, digit ordering and general comparison) in a sample of adults. In a first experiment, we showed that digit comparison performance was most strongly related to digit ordering ability - i.e., the ability to judge whether symbolic numbers are in numerical order. Furthermore, path analyses indicated that the relation between digit comparison and arithmetic was partly mediated by digit ordering and fully mediated when non-numerical (letter) ordering was also entered into the model. In a second experiment, we examined whether a general order working memory component could account for the relation between digit comparison and arithmetic. It could not. Instead, results were more consistent with the notion that fluent access and activation of long-term stored associations between numbers explains the relation between arithmetic and both digit comparison and digit ordering tasks. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Incubation period for campylobacteriosis and its importance in the estimation of incidence related to travel.

    Science.gov (United States)

    Horn, B J; Lake, R J

    2013-10-03

    Differentiation between travel-related and domestic cases of infectious disease is important in managing risk. Incubation periods of cases from several outbreaks of campylobacteriosis in Canada, Europe, and the United States with defined exposure time of less than 24 hours were collated to provide information on the incubation period distribution. This distribution was consistent across the varied outbreaks considered, with 84% (702/832) of cases having an incubation period of four days or less and 1% having an incubation period of eight days or more. The incubation period distribution was incorporated into a model for the number of travel-related cases presenting with symptom onset at given dates after return to their country of residence. Using New Zealand notification data between 2006 and 2010 for cases who had undertaken foreign travel within 10 days prior to symptom onset, we found that 29.6% (67/227 cases; 95% confidence interval (CI): 28.3–30.8%) of these cases were likely to have been domestic cases. When cases with symptom onset prior to arrival were included, the probable domestic cases represented 11.8% (67/571; 95% CI: 11.2–12.3%). Consideration of incubation time distributions and consistent collection of travel start/end dates with symptom onset dates would assist attribution of cases to foreign travel.

  14. Signals of speciation: Volatile organic compounds resolve closely related sagebrush taxa, suggesting their importance in evolution

    Science.gov (United States)

    Deidre M. Jaeger; Justin B. Runyon; Bryce A. Richardson

    2016-01-01

    Volatile organic compounds (VOCs) play important roles in the environmental adaptation and fitness of plants. Comparison of the qualitative and quantitative differences in VOCs among closely related taxa and assessing the effects of environment on their emissions are important steps to deducing VOC function and evolutionary importance.

  15. Relative Numbers of Certain Microbial Groups Present in Compost Used for Mushroom (Agaricus bisporus) Propagation

    Science.gov (United States)

    Fordyce, C.

    1970-01-01

    The relative numbers of microorganisms associated with compost during mushroom production were studied by the dilution plate method. Thermophilic actinomycetes and fungi were isolated with a very high frequency early in the growing season. Although numbers of thermophilic bacteria diminished slowly during the season, the thermophilic fungi and actinomycetes diminished rapidly with the latter disappearing after 6 weeks. Mesophilic fungi other than Agaricus or Trichoderma remained relatively stable throughout the growing period. Agaricus could be isolated between the first and third break. Trichoderma became dominant after the fourth break. The mesophilic bacterial counts diminished during the most productive portion of the mushroom cropping season and then increased to much higher numbers toward the end of the season. PMID:5529631

  16. Effective atomic numbers and electron densities of some biologically important compounds containing H, C, N and O in the energy range 145-1330 keV

    International Nuclear Information System (INIS)

    Manjunathaguru, V; Umesh, T K

    2006-01-01

    A semi-empirical relation which can be used to determine the total attenuation cross sections of samples containing H, C, N and O in the energy range 145-1332 keV has been derived based on the total attenuation cross sections of several sugars, amino acids and fatty acids. The cross sections have been measured by performing transmission experiments in a narrow beam good geometry set-up by employing a high-resolution hyperpure germanium detector at seven energies of biological importance such as 145.4 keV, 279.2 keV, 514 keV, 661.6 keV, 1115.5 keV, 1173.2 keV and 1332.1 keV. The semi-empirical relation can reproduce the experimental values within 1-2%. The total attenuation cross sections of five elements carbon, aluminium, titanium, copper and zirconium measured in the same experimental set-up at the energies mentioned above have been used in a new matrix method to evaluate the effective atomic numbers and the effective electron densities of samples such as cholesterol, fatty acids, sugars and amino acids containing H, C, N and O atoms from their effective atomic cross sections. The effective atomic cross sections are the total attenuation cross sections divided by the total number of atoms of all types in a particular sample. Further, a quantity called the effective atomic weight was defined as the ratio of the molecular weight of a sample to the total number of atoms of all types in it. The variation of the effective atomic number was systematically studied with respect to the effective atomic weight and a new semi-empirical relation for Z eff has been evolved. It is felt that this relation can be very useful to determine the effective atomic number of any sample having H, C, N and O atoms in the energy range 145-1332 keV irrespective of its chemical structure

  17. The Relation between Teachers' Math Talk and the Acquisition of Number Sense within Kindergarten Classrooms

    Science.gov (United States)

    Boonen, Anton J. H.; Kolkman, Meijke E.; Kroesbergen, Evelyn H.

    2011-01-01

    The aim of the present study was to investigate the relation between teachers' math talk and the acquisition of number sense within kindergarten classrooms. The mathematical language input provided by 35 kindergarten teachers was examined with 9 different input categories. The results of this study indicate that the role of each of these math talk…

  18. Sequential optimization of approximate inhibitory rules relative to the length, coverage and number of misclassifications

    KAUST Repository

    Alsolami, Fawaz

    2013-01-01

    This paper is devoted to the study of algorithms for sequential optimization of approximate inhibitory rules relative to the length, coverage and number of misclassifications. Theses algorithms are based on extensions of dynamic programming approach. The results of experiments for decision tables from UCI Machine Learning Repository are discussed. © 2013 Springer-Verlag.

  19. Duration in Poverty-Related Programs and Number of Child Maltreatment Reports.

    Science.gov (United States)

    Kim, Hyunil; Drake, Brett

    2017-02-01

    This study examined the relationship of a family's duration in poverty-related programs (i.e., Aid to Families with Dependent Children/Temporary Assistance for Needy Families and Medicaid) to the subject child's number of maltreatment reports while considering race and baseline neighborhood poverty. Children from a large Midwestern metropolitan area were followed through a linked cross-sector administrative database from birth to age 15. Generalized multilevel models were employed to account for the multilevel structure of the data (i.e., nesting of families within neighborhoods). The data showed a unique and significant contribution of duration in poverty-related programs to the number of maltreatment reports. The predicted number of maltreatment reports increased by between 2.5 and 3.7 times, as duration in poverty-related programs increased from 0 to 9 years. This relationship was consistent between Whites and non-Whites (over 98% Black), but non-Whites showed a significantly lower number of total maltreatment reports while controlling for duration in poverty-related programs. We were unable to find a significant association between child maltreatment reports and baseline neighborhood poverty.

  20. The challenge for genetic epidemiologists: how to analyze large numbers of SNPs in relation to complex diseases.

    Science.gov (United States)

    Heidema, A Geert; Boer, Jolanda M A; Nagelkerke, Nico; Mariman, Edwin C M; van der A, Daphne L; Feskens, Edith J M

    2006-04-21

    Genetic epidemiologists have taken the challenge to identify genetic polymorphisms involved in the development of diseases. Many have collected data on large numbers of genetic markers but are not familiar with available methods to assess their association with complex diseases. Statistical methods have been developed for analyzing the relation between large numbers of genetic and environmental predictors to disease or disease-related variables in genetic association studies. In this commentary we discuss logistic regression analysis, neural networks, including the parameter decreasing method (PDM) and genetic programming optimized neural networks (GPNN) and several non-parametric methods, which include the set association approach, combinatorial partitioning method (CPM), restricted partitioning method (RPM), multifactor dimensionality reduction (MDR) method and the random forests approach. The relative strengths and weaknesses of these methods are highlighted. Logistic regression and neural networks can handle only a limited number of predictor variables, depending on the number of observations in the dataset. Therefore, they are less useful than the non-parametric methods to approach association studies with large numbers of predictor variables. GPNN on the other hand may be a useful approach to select and model important predictors, but its performance to select the important effects in the presence of large numbers of predictors needs to be examined. Both the set association approach and random forests approach are able to handle a large number of predictors and are useful in reducing these predictors to a subset of predictors with an important contribution to disease. The combinatorial methods give more insight in combination patterns for sets of genetic and/or environmental predictor variables that may be related to the outcome variable. As the non-parametric methods have different strengths and weaknesses we conclude that to approach genetic association

  1. A Study on Relative Importance and Priority Regarding Airport Selection Attributes Utilizing AHP

    Directory of Open Access Journals (Sweden)

    Sung-Oun Oh

    2014-10-01

    Full Text Available The aim of this study is to investigate relative importance and priority regarding airport selection attributes using Incheon International Airport and Gimpo International Airport, the two main gateway airports to Seoul, Korea, as the target. For the purpose, a survey was carried out with aviation experts as target utilizing five factors which consist of 15 airport selection attributes. The analysis has been conducted on the relative importance and priority of the airport selection factors by expert group using Analytic Hierarchy Process (AHP. As a result of the analysis, the relative importance of airport selection attributes turned out to be different depending on the expert group. Aviation experts working in government agencies and aviation experts working in educational institutions and research institutes regarded accessibility as the most important airport selection factor, and aviation experts working for airlines and companies related to air travel regarded operation as the most important selection factor.

  2. Imported brucellosis in Denmark: Molecular identification and multiple-locus variable number tandem repeat analysis (MLVA) genotyping of the bacteria

    DEFF Research Database (Denmark)

    Aftab, H.; Dargis, R.; Christensen, J. J.

    2011-01-01

    A polymerase chain reaction was used to identify Brucella species isolated from humans in Denmark. Consecutive analysis of referred bacteria and re-examination of historical isolates identified all as Brucella melitensis. Multiple-locus variable number tandem repeat analysis (MLVA) placed...... the isolates in the previously defined 'East Mediterranean' B. melitensis group....

  3. Optimization of β-decision rules relative to number of misclassifications

    KAUST Repository

    Zielosko, Beata

    2012-01-01

    In the paper, we present an algorithm for optimization of approximate decision rules relative to the number of misclassifications. The considered algorithm is based on extensions of dynamic programming and constructs a directed acyclic graph Δ β (T). Based on this graph we can describe the whole set of so-called irredundant β-decision rules. We can optimize rules from this set according to the number of misclassifications. Results of experiments with decision tables from the UCI Machine Learning Repository are presented. © 2012 Springer-Verlag.

  4. Exploration of Methodological and Participant-Related Influences on the Number of Artifacts in ERP Data

    Directory of Open Access Journals (Sweden)

    Stephanie M. Shields

    2017-11-01

    Full Text Available Event-related potential (ERP data has low signal-to-noise ratio, requiring the conduction of a large number of trials in order to collect sufficient amounts of data for subsequent analysis. Therefore, it would be highly beneficial if researchers could minimize the number of artifacts that occur in the data, minimizing the number of discarded trials and the total number of trials needed. This study thus examined connections between the number of trials that have to be eliminated due to artifacts and a set of methodological variables, physical considerations, and individual differences. In half of the electroencephalography (EEG data collection blocks, naïve undergraduate participants were asked not to blink for the duration of the block (approximately 2.5 minutes, but in the other half, the stimulus set included blinking cues to give participants a chance to blink during blocks. The number of artifacts did not differ based on whether participants were cued to blink during blocks nor which type of block participants experienced first. However, the first block had significantly more artifacts than other blocks, and the third block had significantly fewer. Participants who had previously known one or both investigators had significantly fewer artifacts in their data than participants who had not, but no significant relationship was found between the number of artifacts and any other individual difference or physical consideration examined. These results imply that researchers could preemptively reduce the number of artifacts in their EEG data by including practice blocks and recruiting friends or acquaintances for studies if possible. Based on subjective, unsolicited participant feedback, the authors also recommend having blink cues in data collection blocks in order to make the task more comfortable for participants. Future studies with similar aims could use different equipment setups, e.g. electrode caps, and experimental manipulation of

  5. Subtelomeric Copy Number Variations: The Importance of 4p/4q Deletions in Patients with Congenital Anomalies and Developmental Disability.

    Science.gov (United States)

    Novo-Filho, Gil M; Montenegro, Marília M; Zanardo, Évelin A; Dutra, Roberta L; Dias, Alexandre T; Piazzon, Flavia B; Costa, Taís V M M; Nascimento, Amom M; Honjo, Rachel S; Kim, Chong A; Kulikowski, Leslie D

    2016-01-01

    The most prevalent structural variations in the human genome are copy number variations (CNVs), which appear predominantly in the subtelomeric regions. Variable sizes of 4p/4q CNVs have been associated with several different psychiatric findings and developmental disability (DD). We analyzed 105 patients with congenital anomalies (CA) and developmental and/or intellectual disabilities (DD/ID) using MLPA subtelomeric specific kits (P036 /P070) and 4 of them using microarrays. We found abnormal subtelomeric CNVs in 15 patients (14.3%), including 8 patients with subtelomeric deletions at 4p/4q (53.3%). Additional genomic changes were observed at 1p36, 2q37.3, 5p15.3, 5q35.3, 8p23.3, 13q11, 14q32.3, 15q11.2, and Xq28/Yq12. This indicates the prevalence of independent deletions at 4p/4q, involving PIGG, TRIML2, and FRG1. Furthermore, we identified 15 genes with changes in copy number that contribute to neurological development and/or function, among them CRMP1, SORCS2, SLC25A4, and HELT. Our results highlight the association of genes with changes in copy number at 4p and 4q subtelomeric regions and the DD phenotype. Cytogenomic characterization of additional cases with distal deletions should help clarifying the role of subtelomeric CNVs in neurological diseases. © 2016 S. Karger AG, Basel.

  6. Quality of life related to health chronic kidney disease: Predictive importance of mood and somatic symptoms.

    Science.gov (United States)

    Perales Montilla, Carmen M; Duschek, Stefan; Reyes Del Paso, Gustavo A

    2016-01-01

    To compare the predictive capacity of self-reported somatic symptoms and mood (depression and anxiety) on health-related quality of life (HRQOL) in patients with chronic renal disease. Data were obtained from 52 patients undergoing haemodialysis. Measures included a) the SF-36 health survey, b) the somatic symptoms scale revised (ESS-R) and c) the hospital anxiety and depression scale (HADS). Multiple regression was the main method of statistical analysis. Patients exhibited HRQOL levels below normative values, with anxiety and depression prevalence at 36.5% and 27%, respectively. Mood was the strongest predictor of physical (β=-.624) and mental (β=-.709) HRQOL. Somatic symptoms were also associated with physical HRQOL, but their predictive value was weaker (β=-.270). These results indicate that mood is a superior predictor of the physical and mental components of HRQOL in patients compared with the number and severity of physical symptoms. The data underline the importance of assessing negative emotional states (depression and anxiety) in kidney patients as a basis for intervention, which may facilitate reduction of the impact of chronic renal disease on HRQOL. Copyright © 2016 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.

  7. Conceptual structure and the procedural affordances of rational numbers: relational reasoning with fractions and decimals.

    Science.gov (United States)

    DeWolf, Melissa; Bassok, Miriam; Holyoak, Keith J

    2015-02-01

    The standard number system includes several distinct types of notations, which differ conceptually and afford different procedures. Among notations for rational numbers, the bipartite format of fractions (a/b) enables them to represent 2-dimensional relations between sets of discrete (i.e., countable) elements (e.g., red marbles/all marbles). In contrast, the format of decimals is inherently 1-dimensional, expressing a continuous-valued magnitude (i.e., proportion) but not a 2-dimensional relation between sets of countable elements. Experiment 1 showed that college students indeed view these 2-number notations as conceptually distinct. In a task that did not involve mathematical calculations, participants showed a strong preference to represent partitioned displays of discrete objects with fractions and partitioned displays of continuous masses with decimals. Experiment 2 provided evidence that people are better able to identify and evaluate ratio relationships using fractions than decimals, especially for discrete (or discretized) quantities. Experiments 3 and 4 found a similar pattern of performance for a more complex analogical reasoning task. When solving relational reasoning problems based on discrete or discretized quantities, fractions yielded greater accuracy than decimals; in contrast, when quantities were continuous, accuracy was lower for both symbolic notations. Whereas previous research has established that decimals are more effective than fractions in supporting magnitude comparisons, the present study reveals that fractions are relatively advantageous in supporting relational reasoning with discrete (or discretized) concepts. These findings provide an explanation for the effectiveness of natural frequency formats in supporting some types of reasoning, and have implications for teaching of rational numbers.

  8. Tidal Love numbers and moment-Love relations of polytropic stars

    Science.gov (United States)

    Yip, Kenny L. S.; Leung, P. T.

    2017-12-01

    The physical significance of tidal deformation in astronomical systems has long been known. The recently discovered universal I-Love-Q relations, which connect moment of inertia, quadrupole tidal Love number and spin-induced quadrupole moment of compact stars, also underscore the special role of tidal deformation in gravitational wave astronomy. Motivated by the observation that such relations also prevail in Newtonian stars and crucially depend on the stiffness of a star, we consider the tidal Love numbers of Newtonian polytropic stars whose stiffness is characterized by a polytropic index n. We first perturbatively solve the Lane-Emden equation governing the profile of polytropic stars through the application of the scaled delta expansion method and then formulate perturbation series for the multipolar tidal Love number about the two exactly solvable cases with n = 0 and n = 1, respectively. Making use of these two series to form a two-point Padé approximant, we find an approximate expression of the quadrupole tidal Love number, whose error is less than 2.5 × 10-5 per cent (0.39 per cent) for n ∈ [0, 1] (n ∈ [0, 3]). Similarly, we also determine the mass moments for polytropic stars accurately. Based on these findings, we are able to show that the I-Love-Q relations are in general stationary about the incompressible limit irrespective of the equation of state of a star. Moreover, for the I-Love-Q relations, there is a secondary stationary point near n ≈ 0.4444, thus showing the insensitivity to n for n ∈ [0, 1]. Our investigation clearly tracks the universality of the I-Love-Q relations from their validity for stiff stars such as neutron stars to their breakdown for soft stars.

  9. Assessing the relative importance of health and conformation traits in the cavalier king Charles spaniel.

    Science.gov (United States)

    Wijnrocx, Katrien; François, Liesbeth; Goos, Peter; Buys, Nadine; Janssens, Steven

    2018-01-01

    The selection of a future breeding dog is a complicated task, in which disease characteristics and different traits have to be combined and weighed against one another. Truncation selection, that is the exclusion of affected animals, may be very inefficient when selecting on a large number of traits, and may result in a reduction of the genetic diversity in a population or breed. Selection could be facilitated by the use of a selection index that combines multiple traits or breeding values into one score. This however requires a consideration of their relative value according to their economic weight, which is difficult to express in monetary units for health traits. The use of a choice experiment to derive non-market values might be a solution to this problem. This is a pilot study to assess the potential use of choice experiments to ascertain the public preference and relative importance attached to health- and conformation traits in the selection of a Cavalier King Charles spaniel. The focus was on two prevalent disorders, mitral valve disease and syringomyelia, and on several important conformation traits such as muzzle length and eye shape. Based on available prior information, a Bayesian D-optimal design approach was used to develop a choice experiment and the resulting choice sets. Every participant (breeder or owner) in the choice experiment was presented with a total of 17 choice sets, in which at most four traits could vary to reduce the cognitive burden. A total of 114 respondents participated in the choice experiment and results showed that respondents (breeders/owners) current attitudes were directed towards health (syringomyelia and mitral valve disease), followed by eye shape and level of inbreeding. This approach identifies the value breeders and owners attach to certain traits in the breeding objective. The resulting relative weights, represented as the logworths obtained from the choice experiment, could be an alternative to economic weights. They

  10. The policy relevance of absolute and relative poverty headcounts: What's in a number?

    OpenAIRE

    Notten, Geranda; de Neubourg, Chris

    2007-01-01

    Financial poverty indicators still play an important role in policymaking and evaluation. Countries such as the USA and the EU member states use one or several ‘official’ poverty indicators on which success of poverty reduction policy is regularly monitored. Whereas the US poverty indicator is based on an absolute concept of poverty, the EU Laeken indicator is based on a relative concept. But the consequences of such a decision are considerable. As absolute and relative poverty indicators ref...

  11. Two-colour QCD at finite fundamental quark-number density and related theories

    International Nuclear Information System (INIS)

    Hands, S.J.; Kogut, J.B.; Morrison, S.E.; Sinclair, D.K.

    2001-01-01

    We are simulating SU(2) Yang-Mills theory with four flavours of dynamical quarks in the fundamental representation of SU(2) 'colour' at finite chemical potential, μ for quark number, as a model for QCD at finite baryon number density. In particular we observe that for μ large enough this theory undergoes a phase transition to a state with a diquark condensate which breaks quark-number symmetry. In this phase we examine the spectrum of light scalar and pseudoscalar bosons and see evidence for the Goldstone boson associated with this spontaneous symmetry breaking. This theory is closely related to QCD at finite chemical potential for isospin, a theory which we are now studying for SU(3) colour

  12. Two-colour QCD at finite fundamental quark-number density and related theories

    International Nuclear Information System (INIS)

    Hands, S. J.; Kogut, J. B.; Morrison, S. E.; Sinclair, D. K.

    2000-01-01

    We are simulating SU(2) Yang-Mills theory with four flavours of dynamical quarks in the fundamental representation of SU(2) colour at finite chemical potential, p for quark number, as a model for QCD at finite baryon number density. In particular we observe that for p large enough this theory undergoes a phase transition to a state with a diquark condensate which breaks quark-number symmetry. In this phase we examine the spectrum of light scalar and pseudoscalar bosons and see evidence for the Goldstone boson associated with this spontaneous symmetry breaking. This theory is closely related to QCD at finite chemical potential for isospin, a theory which we are now studying for SU(3) colour

  13. Assessing the relative importance of correlates of loneliness in later life

    DEFF Research Database (Denmark)

    Ejlskov, Linda; Wulff, Jesper; Bøggild, Henrik

    2017-01-01

    OBJECTIVES: Improving the design and targeting of interventions is important for alleviating loneliness among older adults. This requires identifying which correlates are the most important predictors of loneliness. This study demonstrates the use of recursive partitioning in exploring...... the characteristics and assessing the relative importance of correlates of loneliness in older adults. METHOD: Using exploratory regression trees and random forests, we examined combinations and the relative importance of 42 correlates in relation to loneliness at age 68 among 2453 participants from the birth cohort...... study the MRC National Survey of Health and Development. RESULTS: Positive mental well-being, personal mastery, identifying the spouse as the closest confidant, being extrovert and informal social contact were the most important correlates of lower loneliness levels. Participation in organised groups...

  14. Investigation of relation between singular points and number of limit cycles for a rotor-AMBs system

    International Nuclear Information System (INIS)

    Li, J.; Tian, Y.; Zhang, W.

    2009-01-01

    The relation between singular points and the number of limit cycles is investigated for a rotor-active magnetic bearings system with time-varying stiffness and single-degree-of-freedom. The averaged equation of the system is a perturbed polynomial Hamiltonian system of degree 5. The dynamic characteristics of the unperturbed system are first analyzed for a certain parameter group. The number of limit cycles and their configurations of the perturbed system under eight different parametric groups are obtained and the influence of eight control conditions on the number of limit cycles is studied. The results obtained here will play an important leading role in the study of the properties of nonlinear dynamics and control of the rotor-active magnetic bearings system with time-varying stiffness.

  15. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering.

    Science.gov (United States)

    Novitsky, Vlad; Moyo, Sikhulile; Lei, Quanhong; DeGruttola, Victor; Essex, M

    2015-05-01

    To improve the methodology of HIV cluster analysis, we addressed how analysis of HIV clustering is associated with parameters that can affect the outcome of viral clustering. The extent of HIV clustering and tree certainty was compared between 401 HIV-1C near full-length genome sequences and subgenomic regions retrieved from the LANL HIV Database. Sliding window analysis was based on 99 windows of 1,000 bp and 45 windows of 2,000 bp. Potential associations between the extent of HIV clustering and sequence length and the number of variable and informative sites were evaluated. The near full-length genome HIV sequences showed the highest extent of HIV clustering and the highest tree certainty. At the bootstrap threshold of 0.80 in maximum likelihood (ML) analysis, 58.9% of near full-length HIV-1C sequences but only 15.5% of partial pol sequences (ViroSeq) were found in clusters. Among HIV-1 structural genes, pol showed the highest extent of clustering (38.9% at a bootstrap threshold of 0.80), although it was significantly lower than in the near full-length genome sequences. The extent of HIV clustering was significantly higher for sliding windows of 2,000 bp than 1,000 bp. We found a strong association between the sequence length and proportion of HIV sequences in clusters, and a moderate association between the number of variable and informative sites and the proportion of HIV sequences in clusters. In HIV cluster analysis, the extent of detectable HIV clustering is directly associated with the length of viral sequences used, as well as the number of variable and informative sites. Near full-length genome sequences could provide the most informative HIV cluster analysis. Selected subgenomic regions with a high extent of HIV clustering and high tree certainty could also be considered as a second choice.

  16. Chromosome numbers and karyotype evolution in holoparasitic Orobanche (Orobanchaceae) and related genera

    Science.gov (United States)

    Schneeweiss, G.M.; Palomeque, T.; Colwell, A.E.; Weiss-Schneeweiss, H.

    2004-01-01

    Chromosome numbers and karyotypes of species of Orobanche, Cistanche, and Diphelypaea (Orobanchaceae) were investigated, and 108 chromosome counts of 53 taxa, 19 counted for the first time, are presented with a thorough compilation of previously published data. Additionally, karyotypes of representatives of these genera, including Orobanche sects. Orobanche and Trionychon, are reported. Cistanche (x = 20) has large meta- to submetacentric chromosomes, while those of Diphelypaea (x = 19) are medium-sized submeta-to acrocentrics. Within three analyzed sections of Orobanche, sects. Myzorrhiza (x = 24) and Trionychon (x = 12) possess medium-sized submeta- to acrocentrics, while sect. Orobanche (x = 19) has small, mostly meta- to submetacentric, chromosomes. Polyploidy is unevenly distributed in Orobanche and restricted to a few lineages, e.g., O. sect. Myzorrhiza or Orobanche gracilis and its relatives (sect. Orobanche). The distribution of basic chromosome numbers supports the groups found by molecular phylogenetic analyses: Cistanche has x = 20, the Orobanche-group (Orobanche sect. Orobanche, Diphelypaea) has x = 19, and the Phelipanche-group (Orobanche sects. Gymnocaulis, Myzorrhiza, Trionychon) has x = 12, 24. A model of chromosome number evolution in Orobanche and related genera is presented: from two ancestral base numbers, xh = 5 and xh = 6, independent polyploidizations led to x = 20 (Cistanche) and (after dysploidization) x = 19 (Orobanche-group) and to x = 12 and x = 24 (Phelipanche-group), respectively.

  17. Age-related effect of cell death on fiber morphology and number in tongue muscle.

    Science.gov (United States)

    Kletzien, Heidi; Hare, Allison J; Leverson, Glen; Connor, Nadine P

    2018-01-01

    Multiple pathways may exist for age-related tongue muscle degeneration. Cell death is one mechanism contributing to muscle atrophy and decreased function. We hypothesized with aging, apoptosis, and apoptotic regulators would be increased, and muscle fiber size and number would be reduced in extrinsic tongue muscles. Cell death indices, expression of caspase-3 and Bcl-2, and measures of muscle morphology and number were determined in extrinsic tongue muscles of young and old rats. Significant increases in cell death, caspase-3, and Bcl-2 were observed in all extrinsic tongue muscles along with reductions in muscle fiber number in old rats. We demonstrated that apoptosis indices increase with age in lingual muscles and that alterations in apoptotic regulators may be associated with age-related degeneration in muscle fiber size and number. These observed apoptotic processes may be detrimental to muscle function, and may contribute to degradation of cranial functions with age. Muscle Nerve 57: E29-E37, 2018. © 2017 Wiley Periodicals, Inc.

  18. What really matters: An inquiry into the relative importance of dimensions of informal caregiver burden

    NARCIS (Netherlands)

    Exel, N.J.A. van; Brouwer, W.B.F.; Berg, B. van den; Koopmanschap, M.A.; Bos, G.A.M. van den

    2004-01-01

    Objective: Prevailing measures of subjective caregiver burden either have no overall summary score or do not consider the relative importance caregivers attach to different dimensions of burden. Our aim was to assess which dimensions informal caregivers perceive as being important to their overall

  19. What really matters: an inquiry into the relative importance of dimensions of informal caregiver burden

    NARCIS (Netherlands)

    van Exel, N. J. A.; Brouwer, W. B. F.; van den Berg, B.; Koopmanschap, M. A.; van den Bos, G. A. M.

    2004-01-01

    Objective: Prevailing measures of subjective caregiver burden either have no overall summary score or do not consider the relative importance caregivers attach to different dimensions of burden. Our aim was to assess which dimensions informal caregivers perceive as being important to their overall

  20. Cognition and relative importance underlying consumer valuation of park-and-ride facilities

    NARCIS (Netherlands)

    Bos, D.M.; Molin, E.J.E.; Timmermans, H.J.P.; vd Heijden, R.E.C.M.

    2003-01-01

    Results are reported of a study designed to identify the cognitive constructs underlying the valuation of park-and-ride (P&R) facilities and to measure the relative importance attached to the attributes of such facilities. Results show that the reliability of public transport is quite important.

  1. Role of Academic Self-Efficacy in Moderating the Relation between Task Importance and Test Anxiety

    Science.gov (United States)

    Nie, Youyan; Lau, Shun; Liau, Albert K.

    2011-01-01

    Emphasizing task importance, which is regarded as a way of motivating engaged behavior, may increase an individual's anxiety. The present research investigated whether academic self-efficacy could moderate the maladaptive relation between task importance and test anxiety. 1978 and 1670 Grade 9 Singaporean students participated in a survey related…

  2. The Relative Importance of Aesthetics in the Adoption Process of Solar Panels in the Netherlands

    NARCIS (Netherlands)

    Ad Breukel; van Chantal Dijk; Karel Spee

    2016-01-01

    This study focuses on the possible advantage of an aesthetic appeal on the adoption of photovoltaic (PV) cells and panels. Study deals with the importance of this perception of solar panels by potential buyers. It reports the relative importance of aesthetics compared with other attributes, namely

  3. Inequalities for finite trigonometric sums. An interplay: with some series related to harmonic numbers

    Directory of Open Access Journals (Sweden)

    Omran Kouba

    2016-07-01

    Full Text Available Abstract An interplay between the sum of certain series related to harmonic numbers and certain finite trigonometric sums is investigated. This allows us to express the sum of these series in terms of the considered trigonometric sums, and permits us to find sharp inequalities bounding these trigonometric sums. In particular, this answers positively an open problem of Chen (Excursions in Classical Analysis, 2010.

  4. Ombuds’ corner: Is the number of cases involving women related to their percentage in an organization?

    CERN Multimedia

    Vincent Vuillemin

    2013-01-01

    Over the past two years, the Ombuds has seen double the number of cases involving women staff members compared to those involving men, relative to their populations. Two questions can thus be asked: is that a general phenomenon also seen in other organizations? Or is it related to the under-representation of women, namely is this a common situation in organizations with fewer women than men? If so, the Ombuds should notice different statistics in organizations where the number of women and men is comparable.   To answer these questions, several annual reports from international organizations have been analysed. The names of these organizations are kept confidential, as the reports are not public. Relation between the percentage of cases involving women and their percentage in an Organization. The circled data point is CERN’s. The results can be seen in this graph (right), limited solely by the number of Organizations for which such data is available. Note that if the ...

  5. The importance of multidisciplinary teamwork and team climate for relational coordination among teams delivering care to older patients.

    Science.gov (United States)

    Hartgerink, J M; Cramm, J M; Bakker, T J E M; van Eijsden, A M; Mackenbach, J P; Nieboer, A P

    2014-04-01

    To identify predictors of relational coordination among professionals delivering care to older patients. Relational coordination is known to enhance quality of care in hospitals. The underlying mechanisms, however, remain poorly understood. This cross-sectional study was part of a larger evaluation study examining the opportunity to prevent loss of function in older patients due to hospitalization in the Netherlands. This study was performed in spring 2010 among team members delivering care to older hospitalized patients (192 respondents; 44% response rate) in one hospital. Relational coordination was measured by the Relational Coordination survey; team climate by the Team Climate Inventory and questions were asked about participation in multidisciplinary team meetings and disciplines represented in these meetings. To account for the hierarchical structure, a multilevel analysis was performed. Correlation analysis revealed a positive relationship among being female, being a nurse and relational coordination; medical specialists showed a negative relationship. The number of disciplines represented during multidisciplinary team meetings and team climate were positively related with relational coordination. The multilevel analysis showed a positive relationship between the number of disciplines represented during multidisciplinary team meetings and team climate with relational coordination. The enhancement of team climate and attendance of diverse professionals during multidisciplinary team meetings are expected to improve relational coordination. Furthermore, this study underscores the importance of enhancing relational coordination between medical specialists and other professionals. © 2013 The Authors. Journal of Advanced Nursing published by John Wiley & Sons Ltd.

  6. Which factors are important for effectiveness of sport- and health-related apps?

    NARCIS (Netherlands)

    Dallinga, Joan; Janssen, Mark; van der Werf, Jet; Vos, Steven; Deutekom-Baart de la Faille, Marije

    2017-01-01

    Which factors are important for effectiveness of sport- and health-related apps? Results of focus groups with experts. Dallinga, J, van der Werf, J , Janssen, M, Vos, S, Deutekom-Baart de la Faille, M. A huge amount of sport- and health-related smartphone applications (apps) is available in the app

  7. Assessing the relative importance of correlates of loneliness in later life: Gaining insight using recursive partitioning

    DEFF Research Database (Denmark)

    Ejlskov, Linda; Wulff, Jesper; Bøggild, Henrik

    2017-01-01

    and demographic correlates were poor identifiers of loneliness. The regression tree suggested that loneliness was not raised among those with poor mental wellbeing if they identified their partner as closest confidante and had frequent social contact. CONCLUSION: Recursive partitioning can identify which......OBJECTIVES: Improving the design and targeting of interventions is important for alleviating loneliness among older adults. This requires identifying which correlates are the most important predictors of loneliness. This study demonstrates the use of recursive partitioning in exploring...... the characteristics and assessing the relative importance of correlates of loneliness in older adults. METHOD: Using exploratory regression trees and random forests, we examined combinations and the relative importance of 42 correlates in relation to loneliness at age 68 among 2453 participants from the birth cohort...

  8. The Importance of Localized Related Variety for International Diversification of Corporate Technology

    DEFF Research Database (Denmark)

    Dettmann, Eva; Lacasa, Iciar Dominguez; Günther, Jutta

    2016-01-01

    The importance of localized related variety for international diversification of corporate technology, Regional Studies. Internationalization of research and development has increased substantially in recent years. This paper analyses the determinants of spatial distribution of foreign technologi......The importance of localized related variety for international diversification of corporate technology, Regional Studies. Internationalization of research and development has increased substantially in recent years. This paper analyses the determinants of spatial distribution of foreign...... technological activities across 96 regions in Germany. It identifies foreign technological activities by applying the cross-border ownership concept to patent applications. The main proposition is that regions with higher related variety of technological activities between sectors attract more foreign...

  9. Age-ordered shirt numbering reduces the selection bias associated with the relative age effect.

    Science.gov (United States)

    Mann, David L; van Ginneken, Pleun J M A

    2017-04-01

    When placed into age groups for junior sporting competition, the relative differences in age between children leads to a bias in who is evaluated as being talented. While the impact of this relative age effect (RAE) is clear, until now there has been no evidence to show how to reduce it. The aim of this study was to determine whether the selection bias associated with the RAE could be reduced. Talent scouts from an elite football club watched junior games and ranked players on the basis of their potential. Scouts were allocated to one of three groups provided with contrasting information about the age of the players: (1) no age information, (2) players' birthdates or (3) knowledge that the numbers on the playing shirts corresponded to the relative age of the players. Results revealed a significant selection bias for the scouts in the no-age information group, and that bias remained when scouts knew the players' dates-of-birth. Strikingly though, the selection bias was eliminated when scouts watched the games knowing the shirt numbers corresponded to the relative ages of the players. The selection bias associated with the RAE can be reduced if information about age is presented appropriately.

  10. Approximate Bayesian algorithm to estimate the basic reproduction number in an influenza pandemic using arrival times of imported cases.

    Science.gov (United States)

    Chong, Ka Chun; Zee, Benny Chung Ying; Wang, Maggie Haitian

    2018-04-10

    In an influenza pandemic, arrival times of cases are a proxy of the epidemic size and disease transmissibility. Because of intense surveillance of travelers from infected countries, detection is more rapid and complete than on local surveillance. Travel information can provide a more reliable estimation of transmission parameters. We developed an Approximate Bayesian Computation algorithm to estimate the basic reproduction number (R 0 ) in addition to the reporting rate and unobserved epidemic start time, utilizing travel, and routine surveillance data in an influenza pandemic. A simulation was conducted to assess the sampling uncertainty. The estimation approach was further applied to the 2009 influenza A/H1N1 pandemic in Mexico as a case study. In the simulations, we showed that the estimation approach was valid and reliable in different simulation settings. We also found estimates of R 0 and the reporting rate to be 1.37 (95% Credible Interval [CI]: 1.26-1.42) and 4.9% (95% CI: 0.1%-18%), respectively, in the 2009 influenza pandemic in Mexico, which were robust to variations in the fixed parameters. The estimated R 0 was consistent with that in the literature. This method is useful for officials to obtain reliable estimates of disease transmissibility for strategic planning. We suggest that improvements to the flow of reporting for confirmed cases among patients arriving at different countries are required. Copyright © 2018 Elsevier Ltd. All rights reserved.

  11. INSIDE THE NUMBERS: USING PRIVATE COMMERCIAL DATA TO ANALYZE EAST AFRICAN IMPORTED SOAP CONSUMPTION, 1870-1914

    Directory of Open Access Journals (Sweden)

    Laird Jones

    2015-06-01

    Full Text Available Social historians identify soap as a “new need,” and argue its consumption indicates changing notions of bodily cleanliness, beauty and status. Relying largely on qualitative evidence such as traveler and missionary accounts, print advertising and oral interviews, they contend African soap use was influenced by Christian missions, colonial education and branding in the marketplace. Quantitative evidence – limited customs data – neither confirms nor challenges this position. More detailed commercial records, however, paint a somewhat different picture. The East African correspondence of William O’Swald & Co. indicates that soap marketing predated both Christian missions and colonial influence. Further, general purpose laundry soap was the overwhelming best seller. Personal toilette soaps lagged far behind. Laundering imported cotton textiles appeared the motive for initial soap purchases, and perhaps also the first step toward later personal soap use.

  12. The Relative Importance of Persons, Items, Subtests, and Languages to TOEFL Test Variance.

    Science.gov (United States)

    Brown, James Dean

    1999-01-01

    Explored the relative contributions to Test of English as a Foreign Language (TOEFL) score dependability of various numbers of persons, items, subtests, languages, and their various interactions. Sampled 15,000 test takers, 1000 each from 15 different language backgrounds. (Author/VWL)

  13. Accounting for sampling patterns reverses the relative importance of trade and climate for the global sharing of exotic plants

    Science.gov (United States)

    Sofaer, Helen R.; Jarnevich, Catherine S.

    2017-01-01

    AimThe distributions of exotic species reflect patterns of human-mediated dispersal, species climatic tolerances and a suite of other biotic and abiotic factors. The relative importance of each of these factors will shape how the spread of exotic species is affected by ongoing economic globalization and climate change. However, patterns of trade may be correlated with variation in scientific sampling effort globally, potentially confounding studies that do not account for sampling patterns.LocationGlobal.Time periodMuseum records, generally from the 1800s up to 2015.Major taxa studiedPlant species exotic to the United States.MethodsWe used data from the Global Biodiversity Information Facility (GBIF) to summarize the number of plant species with exotic occurrences in the United States that also occur in each other country world-wide. We assessed the relative importance of trade and climatic similarity for explaining variation in the number of shared species while evaluating several methods to account for variation in sampling effort among countries.ResultsAccounting for variation in sampling effort reversed the relative importance of trade and climate for explaining numbers of shared species. Trade was strongly correlated with numbers of shared U.S. exotic plants between the United States and other countries before, but not after, accounting for sampling variation among countries. Conversely, accounting for sampling effort strengthened the relationship between climatic similarity and species sharing. Using the number of records as a measure of sampling effort provided a straightforward approach for the analysis of occurrence data, whereas species richness estimators and rarefaction were less effective at removing sampling bias.Main conclusionsOur work provides support for broad-scale climatic limitation on the distributions of exotic species, illustrates the need to account for variation in sampling effort in large biodiversity databases, and highlights the

  14. Salinity shifts in marine sediment: Importance of number of fluctuation rather than their intensities on bacterial denitrifying community.

    Science.gov (United States)

    Zaghmouri, Imen; Michotey, Valerie D; Armougom, Fabrice; Guasco, Sophie; Bonin, Patricia C

    2018-05-01

    The sensitivity of denitrifying community to salinity fluctuations was studied in microcosms filled with marine coastal sediments subjected to different salinity disturbances over time (sediment under frequent salinity changes vs sediment with "stable" salinity pattern). Upon short-term salinity shift, denitrification rate and denitrifiers abundance showed high resistance whatever the sediment origin is. Denitrifying community adapted to frequent salinity changes showed high resistance when salinity increases, with a dynamic nosZ relative expression level. Marine sediment denitrifying community, characterized by more stable pattern, was less resistant when salinity decreases. However, after two successive variations of salinity, it shifted toward the characteristic community of fluctuating conditions, with larger proportion of Pseudomonas-nosZ, exhibiting an increase of nosZ relative expression level. The impact of long-term salinity variation upon bacterial community was confirmed at ribosomal level with a higher percentage of Pseudomonas and lower proportion of nosZII clade genera. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Relation between surface roughness and number of cathode spots of a low-pressure arc

    International Nuclear Information System (INIS)

    Sato, Atsushi; Iwao, Toru; Yumoto, Motoshige

    2008-01-01

    A remarkable characteristic of the cathode spot of a low-pressure arc is that it can remove an oxide layer preferentially. Recently, cathode spots of a low-pressure arc have been used for cleaning metal oxide surfaces before thermal spraying or surface modification. Nevertheless, few reports have described the cathode spot movement or the oxide removal process. This experiment was carried out using a Fe+C cathode workpiece and a cylindrical copper anode. The cathode spot movement was recorded using a high-speed video camera. The images were later analysed using plasma image processing. The workpiece surface, which was covered with a 9.67 μm thick oxide, was analysed using laser microscopy after processing. The surface roughness and the number of cathode spots showed no direct relation because the current density per cathode spot did not change according to the number of cathode spots.

  16. Relation among different parameters of damaged starch content, falling number and mechanical damage level

    Directory of Open Access Journals (Sweden)

    Živančev Dragan

    2012-01-01

    Full Text Available This work presents examination of damaged starch content expressed by different parameters, which were obtained by iodometric method presented by the Chopin Company using their SD matic instrument on wheat flour samples. Two wheat samples were similar by protein level (14.6 and 14.2% on dry basis matter and different by Falling number values (409 and 121 s. Wheat flours were gained by single-stage and two-stage extraction in laboratory milling system. Eight independent measurements of every wheat flour sample were statistically analyzed by method of variance. It was found that Chopin iodometric method shows that damaged starch content expressed by different parameters is related to Falling number value and damage caused by the pressure and shear forces generated during roller milling.

  17. Relation of the Number of Parity to Left Ventricular Diastolic Function in Pregnancy.

    Science.gov (United States)

    Keskin, Muhammed; Avşar, Şahin; Hayıroğlu, Mert İlker; Keskin, Taha; Börklü, Edibe Betül; Kaya, Adnan; Uzun, Ahmet Okan; Akyol, Burcu; Güvenç, Tolga Sinan; Kozan, Ömer

    2017-07-01

    Left ventricular diastolic dysfunction (LVDD) has been relatively less studied than other cardiac changes during pregnancy. Previous studies revealed a mild diastolic deterioration during pregnancy. However, these studies did not evaluate the long-term effect of parity on left ventricular diastolic function. A comprehensive study evaluating the long-term effect of parity on diastolic function is required. A total of 710 women with various number of parity were evaluated through echocardiography to reveal the status of diastolic function. Echocardiographic parameters were compared among the women by parity number and categorized accordingly: none, 0 to 4 and 4 4 parity and that had 21 and 5.8 times higher than nulliparous group, respectively. In conclusion, according to the present study, grand multiparity but not multiparity, severely deteriorates left ventricular diastolic function. Further studies are warranted to evaluate the risk of gradual diastolic dysfunction after each pregnancy. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. The relative importance of topography and RGD ligand density for endothelial cell adhesion.

    Directory of Open Access Journals (Sweden)

    Guillaume Le Saux

    Full Text Available The morphology and function of endothelial cells depends on the physical and chemical characteristics of the extracellular environment. Here, we designed silicon surfaces on which topographical features and surface densities of the integrin binding peptide arginine-glycine-aspartic acid (RGD could be independently controlled. We used these surfaces to investigate the relative importance of the surface chemistry of ligand presentation versus surface topography in endothelial cell adhesion. We compared cell adhesion, spreading and migration on surfaces with nano- to micro-scaled pyramids and average densities of 6×10(2-6×10(11 RGD/mm(2. We found that fewer cells adhered onto rough than flat surfaces and that the optimal average RGD density for cell adhesion was 6×10(5 RGD/mm(2 on flat surfaces and substrata with nano-scaled roughness. Only on surfaces with micro-scaled pyramids did the topography hinder cell migration and a lower average RGD density was optimal for adhesion. In contrast, cell spreading was greatest on surfaces with 6×10(8 RGD/mm(2 irrespectively of presence of feature and their size. In summary, our data suggest that the size of pyramids predominately control the number of endothelial cells that adhere to the substratum but the average RGD density governs the degree of cell spreading and length of focal adhesion within adherent cells. The data points towards a two-step model of cell adhesion: the initial contact of cells with a substratum may be guided by the topography while the engagement of cell surface receptors is predominately controlled by the surface chemistry.

  19. Individual differences in algebraic cognition: Relation to the approximate number and semantic memory systems.

    Science.gov (United States)

    Geary, David C; Hoard, Mary K; Nugent, Lara; Rouder, Jeffrey N

    2015-12-01

    The relation between performance on measures of algebraic cognition and acuity of the approximate number system (ANS) and memory for addition facts was assessed for 171 ninth graders (92 girls) while controlling for parental education, sex, reading achievement, speed of numeral processing, fluency of symbolic number processing, intelligence, and the central executive component of working memory. The algebraic tasks assessed accuracy in placing x,y pairs in the coordinate plane, speed and accuracy of expression evaluation, and schema memory for algebra equations. ANS acuity was related to accuracy of placements in the coordinate plane and expression evaluation but not to schema memory. Frequency of fact retrieval errors was related to schema memory but not to coordinate plane or expression evaluation accuracy. The results suggest that the ANS may contribute to or be influenced by spatial-numerical and numerical-only quantity judgments in algebraic contexts, whereas difficulties in committing addition facts to long-term memory may presage slow formation of memories for the basic structure of algebra equations. More generally, the results suggest that different brain and cognitive systems are engaged during the learning of different components of algebraic competence while controlling for demographic and domain general abilities. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. SOLAR CYCLE 24: CURIOUS CHANGES IN THE RELATIVE NUMBERS OF SUNSPOT GROUP TYPES

    International Nuclear Information System (INIS)

    Kilcik, A.; Yurchyshyn, V. B.; Ozguc, A.; Rozelot, J. P.

    2014-01-01

    Here, we analyze different sunspot group (SG) behaviors from the points of view of both the sunspot counts (SSCs) and the number of SGs, in four categories, for the time period of 1982 January-2014 May. These categories include data from simple (A and B), medium (C), large (D, E, and F), and decaying (H) SGs. We investigate temporal variations of all data sets used in this study and find the following results. (1) There is a very significant decrease in the large groups' SSCs and the number of SGs in solar cycle 24 (cycle 24) compared to cycles 21-23. (2) There is no strong variation in the decaying groups' data sets for the entire investigated time interval. (3) Medium group data show a gradual decrease for the last three cycles. (4) A significant decrease occurred in the small groups during solar cycle 23, while no strong changes show in the current cycle (cycle 24) compared to the previous ones. We confirm that the temporal behavior of all categories is quite different from cycle to cycle and it is especially flagrant in solar cycle 24. Thus, we argue that the reduced absolute number of the large SGs is largely, if not solely, responsible for the weak cycle 24. These results might be important for long-term space weather predictions to understand the rate of formation of different groups of sunspots during a solar cycle and the possible consequences for the long-term geomagnetic activity

  1. Understanding the increase in the number of childbirth-related leave beneficiaries in Serbia

    Directory of Open Access Journals (Sweden)

    Stanić Katarina

    2017-01-01

    Full Text Available Over the past number of years, the public expenditures for childbirth-related leave benefits have more than doubled – in 2015 amounted to 0.7% GDP in relation to 0.3% GDP in 2002. This increase can mainly be attributed to the increased number of beneficiaries that grew consistently from 24 thousand in 2002 up to 40 thousand in 2015, despite the fact that the annual number of live births has been almost continually decreasing and the registered employment has dropped by almost 20 per cent in the observed period. One of the clear reasons explaining part of this increase is the extension of 3+ order of birth leaves in 2006, from one to two years, which can explain the increase of around 3.5 thousand of beneficiaries. Another reason is high number of beneficiaries using special child-care leave meant for parents with children with disabilities, but which, in reality, is very often used simply as the extension of parental leave. The average number of special child-care leave beneficiaries in the second half of 2015 amounted to 2.8 thousand. When these two effects are taken into account, we still notice significant increase of beneficiaries of around 10 thousand in the observed period. Fictitious employment during the pregnancy can explain this increase to some extent. Available data unambiguously show that a number of women formally employing during the second and third trimester of pregnancy has increased from 800 in 2002 to almost 3.5 thousand monthly average in the second half of 2015. There are two flaws of the childbirth-related leave programme in Serbia, which together lead to the constant increase of the number of beneficiaries. First is the lack of flexibility of the programme, both in terms of eligibility for acquiring the right as well as in terms of flexibility in use. Maternity/parental leave benefit may acquire only those in „standard employment” i.e. employed under employment contract (and entrepreneurs while other type of

  2. Frequency of Home Numeracy Activities Is Differentially Related to Basic Number Processing and Calculation Skills in Kindergartners

    Science.gov (United States)

    Mutaf Yıldız, Belde; Sasanguie, Delphine; De Smedt, Bert; Reynvoet, Bert

    2018-01-01

    Home numeracy has been shown to play an important role in children’s mathematical performance. However, findings are inconsistent as to which home numeracy activities are related to which mathematical skills. The present study disentangled between various mathematical abilities that were previously masked by the use of composite scores of mathematical achievement. Our aim was to shed light on the specific associations between home numeracy and various mathematical abilities. The relationships between kindergartners’ home numeracy activities, their basic number processing and calculation skills were investigated. Participants were 128 kindergartners (Mage = 5.43 years, SD = 0.29, range: 4.88–6.02 years) and their parents. The children completed non-symbolic and symbolic comparison tasks, non-symbolic and symbolic number line estimation tasks, mapping tasks (enumeration and connecting), and two calculation tasks. Their parents completed a home numeracy questionnaire. Results indicated small but significant associations between formal home numeracy activities that involved more explicit teaching efforts (i.e., identifying numerals, counting) and children’s enumeration skills. There was no correlation between formal home numeracy activities and non-symbolic number processing. Informal home numeracy activities that involved more implicit teaching attempts, such as “playing games” and “using numbers in daily life,” were (weakly) correlated with calculation and symbolic number line estimation, respectively. The present findings suggest that disentangling between various basic number processing and calculation skills in children might unravel specific relations with both formal and informal home numeracy activities. This might explain earlier reported contradictory findings on the association between home numeracy and mathematical abilities. PMID:29623055

  3. Frequency of Home Numeracy Activities Is Differentially Related to Basic Number Processing and Calculation Skills in Kindergartners.

    Science.gov (United States)

    Mutaf Yıldız, Belde; Sasanguie, Delphine; De Smedt, Bert; Reynvoet, Bert

    2018-01-01

    Home numeracy has been shown to play an important role in children's mathematical performance. However, findings are inconsistent as to which home numeracy activities are related to which mathematical skills. The present study disentangled between various mathematical abilities that were previously masked by the use of composite scores of mathematical achievement. Our aim was to shed light on the specific associations between home numeracy and various mathematical abilities. The relationships between kindergartners' home numeracy activities, their basic number processing and calculation skills were investigated. Participants were 128 kindergartners ( M age = 5.43 years, SD = 0.29, range: 4.88-6.02 years) and their parents. The children completed non-symbolic and symbolic comparison tasks, non-symbolic and symbolic number line estimation tasks, mapping tasks (enumeration and connecting), and two calculation tasks. Their parents completed a home numeracy questionnaire. Results indicated small but significant associations between formal home numeracy activities that involved more explicit teaching efforts (i.e., identifying numerals, counting) and children's enumeration skills. There was no correlation between formal home numeracy activities and non-symbolic number processing. Informal home numeracy activities that involved more implicit teaching attempts , such as "playing games" and "using numbers in daily life," were (weakly) correlated with calculation and symbolic number line estimation, respectively. The present findings suggest that disentangling between various basic number processing and calculation skills in children might unravel specific relations with both formal and informal home numeracy activities. This might explain earlier reported contradictory findings on the association between home numeracy and mathematical abilities.

  4. Relative Importance and Additive Effects of Maternal and Infant Risk Factors on Childhood Asthma.

    Science.gov (United States)

    Wu, Pingsheng; Feldman, Amy S; Rosas-Salazar, Christian; James, Kristina; Escobar, Gabriel; Gebretsadik, Tebeb; Li, Sherian Xu; Carroll, Kecia N; Walsh, Eileen; Mitchel, Edward; Das, Suman; Kumar, Rajesh; Yu, Chang; Dupont, William D; Hartert, Tina V

    2016-01-01

    Environmental exposures that occur in utero and during early life may contribute to the development of childhood asthma through alteration of the human microbiome. The objectives of this study were to estimate the cumulative effect and relative importance of environmental exposures on the risk of childhood asthma. We conducted a population-based birth cohort study of mother-child dyads who were born between 1995 and 2003 and were continuously enrolled in the PRIMA (Prevention of RSV: Impact on Morbidity and Asthma) cohort. The individual and cumulative impact of maternal urinary tract infections (UTI) during pregnancy, maternal colonization with group B streptococcus (GBS), mode of delivery, infant antibiotic use, and older siblings at home, on the risk of childhood asthma were estimated using logistic regression. Dose-response effect on childhood asthma risk was assessed for continuous risk factors: number of maternal UTIs during pregnancy, courses of infant antibiotics, and number of older siblings at home. We further assessed and compared the relative importance of these exposures on the asthma risk. In a subgroup of children for whom maternal antibiotic use during pregnancy information was available, the effect of maternal antibiotic use on the risk of childhood asthma was estimated. Among 136,098 singleton birth infants, 13.29% developed asthma. In both univariate and adjusted analyses, maternal UTI during pregnancy (odds ratio [OR] 1.2, 95% confidence interval [CI] 1.18, 1.25; adjusted OR [AOR] 1.04, 95%CI 1.02, 1.07 for every additional UTI) and infant antibiotic use (OR 1.21, 95%CI 1.20, 1.22; AOR 1.16, 95%CI 1.15, 1.17 for every additional course) were associated with an increased risk of childhood asthma, while having older siblings at home (OR 0.92, 95%CI 0.91, 0.93; AOR 0.85, 95%CI 0.84, 0.87 for each additional sibling) was associated with a decreased risk of childhood asthma, in a dose-dependent manner. Compared with vaginal delivery, C

  5. Relative Importance and Additive Effects of Maternal and Infant Risk Factors on Childhood Asthma.

    Directory of Open Access Journals (Sweden)

    Pingsheng Wu

    Full Text Available Environmental exposures that occur in utero and during early life may contribute to the development of childhood asthma through alteration of the human microbiome. The objectives of this study were to estimate the cumulative effect and relative importance of environmental exposures on the risk of childhood asthma.We conducted a population-based birth cohort study of mother-child dyads who were born between 1995 and 2003 and were continuously enrolled in the PRIMA (Prevention of RSV: Impact on Morbidity and Asthma cohort. The individual and cumulative impact of maternal urinary tract infections (UTI during pregnancy, maternal colonization with group B streptococcus (GBS, mode of delivery, infant antibiotic use, and older siblings at home, on the risk of childhood asthma were estimated using logistic regression. Dose-response effect on childhood asthma risk was assessed for continuous risk factors: number of maternal UTIs during pregnancy, courses of infant antibiotics, and number of older siblings at home. We further assessed and compared the relative importance of these exposures on the asthma risk. In a subgroup of children for whom maternal antibiotic use during pregnancy information was available, the effect of maternal antibiotic use on the risk of childhood asthma was estimated.Among 136,098 singleton birth infants, 13.29% developed asthma. In both univariate and adjusted analyses, maternal UTI during pregnancy (odds ratio [OR] 1.2, 95% confidence interval [CI] 1.18, 1.25; adjusted OR [AOR] 1.04, 95%CI 1.02, 1.07 for every additional UTI and infant antibiotic use (OR 1.21, 95%CI 1.20, 1.22; AOR 1.16, 95%CI 1.15, 1.17 for every additional course were associated with an increased risk of childhood asthma, while having older siblings at home (OR 0.92, 95%CI 0.91, 0.93; AOR 0.85, 95%CI 0.84, 0.87 for each additional sibling was associated with a decreased risk of childhood asthma, in a dose-dependent manner. Compared with vaginal delivery, C

  6. Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?

    Directory of Open Access Journals (Sweden)

    Malheiros Suzana M. F.

    2001-01-01

    Full Text Available Coronary artery bypass surgery (CABG without cardiopulmonary bypass (CPB may potentially reduce the number of microembolic signals (MES associated with aortic manipulation or generated by the pump circuit, resulting in a better neurologic outcome after surgery. Our aim was to compare the frequency of MES and neurologic complications in CABG with and without CPB. Twenty patients eligible to routine CABG without CPB were randomized to surgery with CPB and without CPB and continuously monitored by transcranial Doppler. Neurologic examination was performed in all patients before and after surgery. The two groups were similar with respect to demographics, risk factors, grade of aortic atheromatous disease and number of grafts. The frequency of MES in the nonCPB group was considerably lower than in CPB patients, however, we did not observe any change in the neurologic examination during the early postoperative period. Neurologic complications after CABG may be related to the size and composition of MES rather than to their absolute numbers. A large prospective multicentric randomized trial may help to elucidate this complex issue.

  7. The importance of building construction materials relative to other factors affecting structure survival during wildfire

    Science.gov (United States)

    Syphard, Alexandra D.; Brennan, Teresa J.; Keeley, Jon E.

    2017-01-01

    Structure loss to wildfire is a serious problem in wildland-urban interface areas across the world. Laboratory experiments suggest that fire-resistant building construction and design could be important for reducing structure destruction, but these need to be evaluated under real wildfire conditions, especially relative to other factors. Using empirical data from destroyed and surviving structures from large wildfires in southern California, we evaluated the relative importance of building construction and structure age compared to other local and landscape-scale variables associated with structure survival. The local-scale analysis showed that window preparation was especially important but, in general, creating defensible space adjacent to the home was as important as building construction. At the landscape scale, structure density and structure age were the two most important factors affecting structure survival, but there was a significant interaction between them. That is, young structure age was most important in higher-density areas where structure survival overall was more likely. On the other hand, newer-construction structures were less likely to survive wildfires at lower density. Here, appropriate defensible space near the structure and accessibility to major roads were important factors. In conclusion, community safety is a multivariate problem that will require a comprehensive solution involving land use planning, fire-safe construction, and property maintenance.

  8. Number of meals eaten in relation to weight status among Norwegian adolescents.

    Science.gov (United States)

    Vik, Frøydis N; Overby, Nina C; Lien, Nanna; Bere, Elling

    2010-11-01

    To assess the relationship between number of meals eaten and weight status, and to assess potential confounders of this relationship. A total of 2870 (participation rate: 85%) 9th and 10th graders (mean age: 15.5 years) at 33 schools completed questionnaires in May 2005. Number of meals was measured with questions asking whether they ate breakfast, lunch, dinner, and supper the day before, giving a scale ranging from zero to four meals/day. Data on gender, height, weight, education plans, intake of fruits and vegetables, consumption of unhealthy snacks, TV/computer time, physical activity level, and dieting were also collected. The proportions of overweight adolescents related to the number of meals eaten were: 10% (0-1 meals, n = 107), 18% (2 meals, n = 399), 14% (3 meals, n = 925), and 10% (4 meals, n = 1402), p ≤ 0.001. Low education plans, high TV/computer time, low physical activity level, and dieting were all positively associated with both being overweight and not having four meals. Being a boy was positively associated with being overweight but negatively associated with not having four meals. High intake of unhealthy snacks was negatively associated with being overweight, but positively associated with not having four meals. In a logistic regression analysis, adjusting for all variables mentioned, odds ratio for being overweight were 0.8 (95% CI 0.3-1.9), 1.8 (95% CI 1.2-2.7) and 1.6 (95% CI 1.2-2.3), respectively, for eating one or zero, two, and three meals compared to four meals. Eating four meals/day was significantly negatively related to being overweight, also when controlling for potential confounding factors.

  9. The relative importance of health, income and social relations for subjective well-being: An integrative analysis.

    Science.gov (United States)

    Lamu, Admassu N; Olsen, Jan Abel

    2016-03-01

    There is much evidence that health, income and social relationships are important for our well-being, but little evidence on their relative importance. This study makes an integrative analysis of the relative influence of health related quality of life (HRQoL), household income and social relationships for subjective well-being (SWB), where SWB is measured by the first three of the five items on the satisfaction with life scale (SWLS). In a comprehensive 2012 survey from six countries, seven disease groups and representative healthy samples (N = 7933) reported their health along several measures of HRQoL. A Shapley value decomposition method measures the relative importance of health, income and social relationships, while a quantile regression model tests how the effects of each of the three predictors vary across different points of SWB distributions. Results are compared with the standard regression. The respective marginal contribution of social relationships, health and income to SWB (as a share of goodness-of-fit) is 50.2, 19.3 and 7.3% when EQ-5D-5L is used as a measure of health. These findings are consistent across models based on five alternative measures of HRQoL. The influence of the key determinants varied significantly between low and high levels of the SWB distribution, with health and income having stronger influence among those with relatively lower SWB. Consistent with several studies, income has a significantly positive association with SWB, but with diminishing importance. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. The Relative Importance of Motives for International Self-Initiated Mobility

    Science.gov (United States)

    Thorn, Kaye

    2009-01-01

    Purpose: This paper aims to explore the relative importance of the motives and sub-motives which influence a highly educated individual's decision to move across global boundaries. Design/methodology/approach: The approach takes a multi-dimensional perspective of mobility, resulting in the development of a range of motives for self-initiated…

  11. Relative importance of vertebrates and invertebrates in epigeaic weed seed predation in organic cereal fields

    NARCIS (Netherlands)

    Westerman, P.R.; Hofman, A.; Vet, L.E.M.; Van der Werf, W.

    2003-01-01

    Exclosure trials were conducted in four organic cereal fields in The Netherlands in 1999 and 2000 to determine the relative importance of vertebrates and invertebrates in weed seed predation. The trials showed that seed predation by vertebrates was rather consistent and predictable, occurring on all

  12. Relative importance of cohesion and adhesion for sensory stickiness of semisolid foods

    NARCIS (Netherlands)

    Dunnewind, B.; Janssen, A.M.; Vliet, T. van; Weenen, H.

    2004-01-01

    The relative importance of cohesion and adhesion for sensory stickness of semisolid foods was investigated using a texture analyzers. Products included commercial mayon-naises, custard desserts and warm sauces which varied in apparent viscosity between 0.3 and 18.3 Pa.s. It was observed that the

  13. New EU Policies Towards Animal Welfare: The Relative Importance of Pig Castration

    NARCIS (Netherlands)

    Kallas, Z.; Gil, J.M.; Panella-Riera, N.; Blanch, M.; Tacken, G.M.L.; Chevillon, P.; Roest, de K.; Oliver, M.A.

    2012-01-01

    Animal welfare is becoming one of the most contentious issues in animal husbandry and meat production industries. We assess the relative importance of animal welfare, with respect to pig castration and the avoidance of boar taint, alongside different attributes of pork meat, amongst consumers in six

  14. Job performance ratings : The relative importance of mental ability, conscientiousness, and career adaptability

    NARCIS (Netherlands)

    Ohme, Melanie; Zacher, Hannes

    According to career construction theory, continuous adaptation to the work environment is crucial to achieve work and career success. In this study, we examined the relative importance of career adaptability for job performance ratings using an experimental policy-capturing design. Employees (N =

  15. The Relative Importance of Low Significance Level and High Power in Multiple Tests of Significance.

    Science.gov (United States)

    Westermann, Rainer; Hager, Willi

    1983-01-01

    Two psychological experiments--Anderson and Shanteau (1970), Berkowitz and LePage (1967)--are reanalyzed to present the problem of the relative importance of low Type 1 error probability and high power when answering a research question by testing several statistical hypotheses. (Author/PN)

  16. The ring of fire: the relative importance of fuel packing versus intrinsic leaf flammability

    NARCIS (Netherlands)

    Grootemaat, S.; Wright, I.J.; Cornelissen, J.H.C.; Viegas, D.X.

    2014-01-01

    Two different experimental set-ups were used to disentangle the relative importance of intrinsic leaf traits versus fuel packing for the flammability in fuel beds. Dried leaves from 25 Australian perennial species were burnt in fuel bed rings under controlled conditions. The flammability parameters

  17. Importance of Health-Related Fitness Knowledge to Increasing Physical Activity and Physical Fitness

    Science.gov (United States)

    Ferkel, Rick C.; Judge, Lawrence W.; Stodden, David F.; Griffin, Kent

    2014-01-01

    Physical inactivity is expanding across all ages in the United States. Research has documented a deficiency in health-related fitness knowledge (HRFK) among elementary- through college-aged students. The need for a credible and reliable resource that provides research-based information regarding the importance of HRFK is significant. The purpose…

  18. Business Student Preferences: Exploring the Relative Importance of Web Management in Course Design

    Science.gov (United States)

    Taylor, Steven A.; Humphreys, Michael; Singley, Roger; Hunter, Gary L.

    2004-01-01

    The following study investigates the relative importance of Web management practices in business curricular pedagogy from an undergraduate student perspective. Using conjoint methodology, the results suggest that students early in their program of studies tend to most value (more) tests in terms of course attributes, while students later in their…

  19. Online shopping interface components: relative importance as peripheral and central cues.

    Science.gov (United States)

    Warden, Clyde A; Wu, Wann-Yih; Tsai, Dungchun

    2006-06-01

    The Elaboration Likelihood Model (ELM) uses central (more thoughtful) and peripheral (less thoughtful) routes of persuasion to maximize communication effectiveness. This research implements ELM to investigate the relative importance of different aspects of the user experience in online shopping. Of all the issues surrounding online shopping, convenience, access to information, and trust were found to be the most important. These were implemented in an online conjoint shopping task. Respondents were found to use the central route of the ELM on marketing messages that involved issues of minimizing travel, information access, and assurances of system security. Users employed the peripheral ELM route when considering usability, price comparison, and personal information protection. A descriptive model of Web-based marketing components, their roles in the central and peripheral routes, and their relative importance to online consumer segments was developed.

  20. Burnout and Engagement: Relative Importance of Predictors and Outcomes in Two Health Care Worker Samples.

    Science.gov (United States)

    Fragoso, Zachary L; Holcombe, Kyla J; McCluney, Courtney L; Fisher, Gwenith G; McGonagle, Alyssa K; Friebe, Susan J

    2016-06-09

    This study's purpose was twofold: first, to examine the relative importance of job demands and resources as predictors of burnout and engagement, and second, the relative importance of engagement and burnout related to health, depressive symptoms, work ability, organizational commitment, and turnover intentions in two samples of health care workers. Nurse leaders (n = 162) and licensed emergency medical technicians (EMTs; n = 102) completed surveys. In both samples, job demands predicted burnout more strongly than job resources, and job resources predicted engagement more strongly than job demands. Engagement held more weight than burnout for predicting commitment, and burnout held more weight for predicting health outcomes, depressive symptoms, and work ability. Results have implications for the design, evaluation, and effectiveness of workplace interventions to reduce burnout and improve engagement among health care workers. Actionable recommendations for increasing engagement and decreasing burnout in health care organizations are provided. © 2016 The Author(s).

  1. Perceived importance of sustainability and ethics related to fish: a consumer behavior perspective.

    Science.gov (United States)

    Verbeke, Wim; Vanhonacker, Filiep; Sioen, Isabelle; Van Camp, John; De Henauw, Stefaan

    2007-11-01

    Although sustainability and ethics are of increasing public importance, little research has been conducted to reveal its association with fish consumer behavior. Cross-sectional data were collected through a postal self-administered survey (June 2005) from a sample of 381 Flemish women aged 20-50 years. Consumers attach high perceived importance to sustainability and ethics related to fish. However, this perceived importance is neither correlated with fish consumption frequency nor with general attitude toward eating fish. Refusing to eat wild fish is grounded in sustainability and ethical concerns, whereas the decision not to eat farmed fish is associated with a lower expected intrinsic quality rather than shaped by importance attached to sustainability and ethical issues.

  2. [Prenatal control related to the number of consultations as hyperglycemia diagnostic method].

    Science.gov (United States)

    Hernández-Valencia, Marcelino; Carrillo Pacheco, Adia

    2002-12-01

    The impaired in the metabolism of the carbohydrates in a previously healthy woman who develops hyperglycemia during the pregnancy is know as gestational diabetes, the maternal-fetal mortality and morbility is almost the same one that a pregnant normal woman, if the metabolic dysfunction is appropriately controlled, the complications can be treated with success if the pregnant one attends prenatal control. The aim of this study was to know the relationship between number of consultations and the hyperglycemia frequency to settle down. 304 pregnant patients were studied that who request childbirth attention at emergency room of the gynecology and obstetrics service were studied; two groups were formed. The first group, 176 patients with term pregnancy in inadequate control with four or less prenatal consultations. The second group, 128 patients with five or more prenatal consultations. All had a fast of at least 4 hours, to take them a sample of blood and to determine the glucose during their entrance with initial childbirth labor. There was difference in the number of consultations that received each group with 1.4 +/- 1.0 consultations for the irregular group and 6.5 +/- 1.1 for the group with regular control. The pregnant ones with no prenatal consultation presented the biggest hyperglycemia percentage, but this percentage diminished as the pregnant ones attended to a bigger number of consultations, since they were detected the dysfunction of glucose on time and they could be treated appropriately. The glycemia was normal in all the patients that had more than 6 prenatal consultations because hyperglycemia was detected in 55 (31.2%) patients of the group with irregular prenatal control, in comparison with 4 (3.1%) of those with appropriate control (p control with a smaller number of prenatal consultations, they have the biggest hyperglycemia percentage, because it was not possible to detect this dysfunction in an opportune way, this situation demonstrates the

  3. The relative importance of wife abuse as a risk factor for violence against children.

    Science.gov (United States)

    Tajima, E A

    2000-11-01

    To investigate the relative importance of wife abuse as a risk factor for physical child abuse, physical punishment, and verbal child abuse. The study explored the importance of wife abuse relative to blocks of parent, child, and family characteristics and also relative to specific risk factors. This study re-analyzed a sub-sample (N = 2,733) of data from the 1985 National Family Violence Survey. Hierarchical logistic regressions were conducted, using five different criterion variables measuring physical child abuse, physical punishment, and verbal abuse separately and in combination. Blocks of parent, child, and family characteristics were more important predictors of violence towards children than was wife abuse, though the presence of wife abuse in the home was a consistently significant specific risk factor for all forms of violence against children. Of specific risk factors, a respondent's history of having been hit as an adolescent was a larger risk factor for physical child abuse than was wife abuse. Wife abuse was an important predictor of physical punishment. Non-violent marital discord was a greater factor in predicting likelihood of verbal child abuse than was wife abuse. Though this study confirms the association between wife abuse and violence towards children, it cautions us not to overlook the contribution of other factors in our attempts to understand the increased risk attributed to wife abuse.

  4. The perceived importance of physical activity: associations with psychosocial and health-related outcomes.

    Science.gov (United States)

    Wójcicki, Thomas R; Szabo, Amanda N; White, Siobhan M; Mailey, Emily L; Kramer, Arthur F; McAuley, Edward

    2013-03-01

    The purpose of this study was to assess the extent to which participation in a 12-month exercise program changed the degree of importance that older adults attached to physical activity. In addition, associations among changes in physical activity importance and health-related and psychosocial outcomes were examined. Community-dwelling older adults (N = 179) were recruited to participate in a 12-month exercise trial examining the association between changes in physical activity and fitness with changes in brain structure and psychological health. Participants were randomly assigned to a walking condition or a flexibility, toning, and balance condition. Physical, psychological, and cognitive assessments were taken at months 0, 6, and 12. Involvement in a 12-month exercise program increased the importance that participants placed on physical activity; this positive change was similar across exercise condition and sex. Changes in importance, however, were only associated with changes in physical health status and outcome expectations for exercise midway through the intervention. There were no significant associations at the end of the program. Regular participation in physical activity can positively influence the perceived importance of the behavior itself. Yet, the implications of such changes on physical activity-related outcomes remain equivocal and warrant further investigation.

  5. The Relation between the Number of Hours That Authorize the Sale of Alcoholic Beverages and Violence

    Directory of Open Access Journals (Sweden)

    Carlos Huaco

    2012-07-01

    Full Text Available Background: La Victoria was considered, the most violent area in Lima City, the local governmentenforced a public policy regarding number of hours for selling of alcoholic beverages inJanuary 2007. The study was designed to compare its results in Violence between one districtwith the law and other without the law.Methods: This retrospective cross-sectional was an ecological study with a chronological andgeographical comparison between La Victoria, with the restriction and Cercado de Lima withoutthe ban. The participants in the study were patients from a local National Hospital, with aggressionsfrom fighting, or were wounded in traffic accidents, and violent death bodies at NationalInstitute of Legal Medicine. Data were analyzed, using clinical histories (2006 vs. 2007-8 and necropsies(2005-6 vs. 2007-8Results: The reduction of aggression rates at La Victoria in 2007 and 2008 in comparison to2006, were 40.7% and 36.4% respectively (P< 0.05. It was related to the number of hours of liquorauthorized selling Y= -11.25+27.32 X (P<0.05. There was a reduction of 44% in homicide(P<0.05 and 35% in suicide rates between biennia’s. The female/ male ratio of homicideschanged from 1/7.3 to 1/4.6. A significant increase in the rate of alcohol positive dead bodieswas observed (20.3% to 41.5%, (Relative Risk (RR = 2.03, (95% Confidence Interval (CI =(1.09-3.8, χ²(1=5.24, ( P< 0.05.Conclusions: The reduction of violence was probably due to the ban, indicating the importanceof programs to control alcohol consumption which lead to decrease the rate of violence and its’consequences like homicides, impulsive violence.

  6. Parents' Judgments of the Acceptability and Importance of Socially Interactive Robots for Intervening with Young Children with Disabilities. Social Robots Research Reports, Number 1

    Science.gov (United States)

    Dunst, Carl J.; Trivette, Carol M.; Prior, Jeremy; Hamby, Deborah W.; Embler, Davon

    2013-01-01

    A number of different types of socially interactive robots are being used as part of interventions with young children with disabilities to promote their joint attention and language skills. Parents' judgments of two dimensions (acceptance and importance) of the social validity of four different social robots were the focus of the study described…

  7. Influence of contact definitions in assessment of the relative importance of social settings in disease transmission risk.

    Directory of Open Access Journals (Sweden)

    Kirsty J Bolton

    Full Text Available BACKGROUND: Realistic models of disease transmission incorporating complex population heterogeneities require input from quantitative population mixing studies. We use contact diaries to assess the relative importance of social settings in respiratory pathogen spread using three measures of person contact hours (PCH as proxies for transmission risk with an aim to inform bipartite network models of respiratory pathogen transmission. METHODS AND FINDINGS: Our survey examines the contact behaviour for a convenience sample of 65 adults, with each encounter classified as occurring in a work, retail, home, social, travel or "other" setting. The diary design allows for extraction of PCH-interaction (cumulative time in face-face conversational or touch interaction with contacts--analogous to the contact measure used in several existing surveys--as well as PCH-setting (product of time spent in setting and number of people present and PCH-reach (product of time spent in setting and number of people in close proximity. Heterogeneities in day-dependent distribution of risk across settings are analysed using partitioning and cluster analyses and compared between days and contact measures. Although home is typically the highest-risk setting when PCH measures isolate two-way interactions, its relative importance compared to social and work settings may reduce when adopting a more inclusive contact measure that considers the number and duration of potential exposure events. CONCLUSIONS: Heterogeneities in location-dependent contact behaviour as measured by contact diary studies depend on the adopted contact definition. We find that contact measures isolating face-face conversational or touch interactions suggest that contact in the home dominates, whereas more inclusive contact measures indicate that home and work settings may be of higher importance. In the absence of definitive knowledge of the contact required to facilitate transmission of various

  8. Why are agricultural impacts of climate change so uncertain? The importance of temperature relative to precipitation

    International Nuclear Information System (INIS)

    Lobell, David B; Burke, Marshall B

    2008-01-01

    Estimates of climate change impacts are often characterized by large uncertainties that reflect ignorance of many physical, biological, and socio-economic processes, and which hamper efforts to anticipate and adapt to climate change. A key to reducing these uncertainties is improved understanding of the relative contributions of individual factors. We evaluated uncertainties for projections of climate change impacts on crop production for 94 crop-region combinations that account for the bulk of calories consumed by malnourished populations. Specifically, we focused on the relative contributions of four factors: climate model projections of future temperature and precipitation, and the sensitivities of crops to temperature and precipitation changes. Surprisingly, uncertainties related to temperature represented a greater contribution to climate change impact uncertainty than those related to precipitation for most crops and regions, and in particular the sensitivity of crop yields to temperature was a critical source of uncertainty. These findings occurred despite rainfall's important contribution to year-to-year variability in crop yields and large disagreements among global climate models over the direction of future regional rainfall changes, and reflect the large magnitude of future warming relative to historical variability. We conclude that progress in understanding crop responses to temperature and the magnitude of regional temperature changes are two of the most important needs for climate change impact assessments and adaptation efforts for agriculture

  9. Relative importance index (RII) in ranking of procrastination factors among university students

    Science.gov (United States)

    Aziz, Nazrina; Zain, Zakiyah; Mafuzi, Raja Muhammad Zahid Raja; Mustapa, Aini Mastura; Najib, Nur Hasibah Mohd; Lah, Nik Fatihah Nik

    2016-08-01

    Procrastination is the action of delaying or postponing something such as making a decision or starting or completing some tasks or activities. According to previous studies, students who have a strong tendency to procrastinate get low scores in their tests, resulting in poorer academic performance compared to those who do not procrastinate. This study aims to identify the procrastination factors in completing assignments among three groups of undergraduate students. The relative importance of procrastination factors was quantified by the relative importance index (RII) method prior to ranking. A multistage sampling technique was used in selecting the sample. The findings revealed that `too many works in one time' is one of the top three factors contributing to procrastination in all groups.

  10. Relative Importance of Political Instability and Economic Variables on Perceived Country Creditworthiness

    OpenAIRE

    Suk Hun Lee

    1993-01-01

    This paper examines the relative importance of political instability and economic variables on perceived country creditworthiness. Our results indicate that both political instability and economic variables are taken into account in evaluating country creditworthiness; however, it appears that bankers assign larger weight to economic performances, which we except of reflect longer term political stability. In addition, the frequency of changes in the regime and armed conflict, both proxying f...

  11. On the Relative Importance of Corporate Working Capital Determinants: Findings from the EU Countries

    OpenAIRE

    Julia Koralun-Bereźnicka

    2014-01-01

    The corporate finance literature traditionally abounds in both theoretical discussion and empirical research concerning financing and long-term investment decisions. Managing short-term resources appears to be a much less remarkable issue, despite this resource's significant share of a firm's balance sheet and the time and effort required to manage the current assets and liabilities. This article provides insights into the relative importance of the selected working capital determinants from ...

  12. Energy saving in Swedish households. The (relative) importance of environmental attitudes

    International Nuclear Information System (INIS)

    Martinsson, Johan; Lundqvist, Lennart J.; Sundstroem, Aksel

    2011-01-01

    The objectives for energy saving in the housing sector set by recent Swedish energy and climate policies are quite demanding. This article uses nation-wide Swedish survey data from 2004 to 2007 to explore the potential for achieving those targets. Earlier findings that socio-economic characteristics such as age, housing type and income are strongly linked to higher propensities to save on heating and hot water usage are confirmed by ordered logistic regression models. However, general environmental attitudes are also found to play a crucial role. When assessing the relative importance of socio-economic factors and environmental attitudes, the effect on energy saving is generally greater for the former than the latter. In addition, important interaction effects are identified. In relative terms, the effect of environmental attitudes is clearly stronger among households in apartment blocks than among those in detached housing, and stronger among households with higher income than among those with lower income. We end by discussing the implications for the selection and targeting of policy measures to tap the energy savings potential in the population. - Highlights: → We use Swedish survey data to analyse the determinants of household energy saving. → Housing type plays a crucial role for individuals' propensity to save energy. → Environmental attitudes are clearly more important in high-income households. → Environmental attitudes are clearly more important for people in apartment blocks.

  13. Relative importance and interrelations between psychosocial factors and individualized quality of life of hemodialysis patients.

    Science.gov (United States)

    Tovbin, David; Gidron, Yori; Jean, Tzipora; Granovsky, Ricardo; Schnieder, Alla

    2003-09-01

    Since quality of life (QOL) of hemodialysis (HD) patients is low and frequently difficult to improve by medical therapy, it is important to identify psychosocial correlates and life-domains important for HD patients' QOL. Our hypothesis was that psychosocial factors reflecting appraisal, external and internal resources/impediments correlate with QOL and compensate for adverse effects of disease-related variables on QOL. Forty-eight chronic HD-patients identified and rank-ordered life-domains important for QOL and rated their level of satisfaction with those domains. This was performed using a slightly modified version of the Self-Evaluated Individualized QOL (SEiQOL) Scale. Psychosocial factors included perceived-control (PC), social-support and hostility. Demographic and disease-related factors included age, gender, cardiovascular disease (CVD), diabetes, hematocrit, albumin and C-reactive protein. QOL was significantly correlated with PC (r = 0.65) and social-support (r = 0.38), and inversely correlated with hostility (r = -0.31), diabetes and hypoalbuminemia (all at least p < 0.05). PC mediated effects of certain variables (e.g., albumin, gender, hostility) and moderated effects of little social-support and hypoalbuminemia on QOL. Patients' most important QOL domains were health, with which satisfaction was lowest, followed by family, with which satisfaction was highest. Pending replication with larger samples, assessment and enhancement of PC may improve HD patients' QOL.

  14. The relative importance of water temperature and residence time in predicting cyanobacteria abundance in regulated rivers.

    Science.gov (United States)

    Cha, YoonKyung; Cho, Kyung Hwa; Lee, Hyuk; Kang, Taegu; Kim, Joon Ha

    2017-11-01

    Despite a growing awareness of the problems associated with cyanobacterial blooms in rivers, and particularly in regulated rivers, the drivers of bloom formation and abundance in rivers are not well understood. We developed a Bayesian hierarchical model to assess the relative importance of predictors of summer cyanobacteria abundance, and to test whether the relative importance of each predictor varies by site, using monitoring data from 16 sites in the four major rivers of South Korea. The results suggested that temperature and residence time, but not nutrient levels, are important predictors of summer cyanobacteria abundance in rivers. Although the two predictors were of similar significance across the sites, the residence time was marginally better in accounting for the variation in cyanobacteria abundance. The model with spatial hierarchy demonstrated that temperature played a consistently significant role at all sites, and showed no effect from site-specific factors. In contrast, the importance of residence time varied significantly from site to site. This variation was shown to depend on the trophic state, indicated by the chlorophyll-a and total phosphorus levels. Our results also suggested that the magnitude of weir inflow is a key factor determining the cyanobacteria abundance under baseline conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Relative importance of habitat area and isolation for bird occurrence patterns in a naturally patchy landscape

    Science.gov (United States)

    Wilson, T.L.; Johnson, E.J.; Bissonette, J.A.

    2009-01-01

    There is debate among ecologists about whether total habitat area or patch arrangement contributes most to population and/or community responses to fragmented or patchy landscapes. We tested the relative effects of patch area and isolation for predicting bird occurrence in a naturally patchy landscape in the Bear River Mountains of Northern Utah, USA. We selected focal patches (mountain meadows) ranging in elevation from 1,920 to 2,860 m and in size from 0.6 to 182 ha. Breeding birds were sampled in each focal meadow during the summers of 2003 and 2004 using variable-distance point transects. Logistic regression and likelihood-based model selection were used to determine the relationship between likelihood of occurrence of three bird species (Brewer's sparrow, vesper sparrow, and white-crowned sparrow) and area, isolation, and proximity metrics. We used model weights and model-averaged confidence intervals to assess the importance of each predictor variable. Plots of area versus isolation were used to evaluate complex relationships between the variables. We found that meadow area was the most important variable for explaining occurrence for two species, and that isolation was the most important for the other. We also found that the absolute distance was more appropriate for evaluating isolation responses than was the species-specific proximity metric. Our findings add clarity to the debate between ecologists regarding the relative importance of area and isolation in species responses to patchy landscapes.

  16. Mitigation of naphthenate related production upsets in high TAN (Total Acid Number) crude oil

    Energy Technology Data Exchange (ETDEWEB)

    Ostojic, Nik [Maersk Oil, Copenhagen (Denmark); Vijn, Pieter; Reiners, Robert [Champion Technologies Europe BV, Delden (Netherlands)

    2012-07-01

    This paper describes a strategy for prediction, evaluation and mitigation of calcium naphthenate related production problems. Developing fields with acidic crude in the North Sea, West Africa, Bohai Bay (China) and Brazil is becoming more common in recent years. The high acid crude contains a considerable amount of naphthenic acids, typically having a Total Acid Number (TAN) higher than 0.5 mg KOH/g. Formation of either hard type 'calcium naphthenate precipitates' or soft type 'sodium carboxylate/emulsions' during crude oil production can lead to severe flow assurance and separation problems. In severe cases this may lead to production shutdowns to clean-up the equipment. A number of different naphthenate mitigation approaches have been published but no one particular approach is considered to be the most efficient as it depends significantly on the particular field conditions. Initially, this problem was addressed by deploying large volumes of (usually organic) acid, but more recently high efficiency low dose naphthenate inhibitors have been introduced. For predicting naphthenate scaling potential, methods were developed to determine the concentration of 1230 Dalton naphthenic tetra acid (ARN acids) in either deposit or crude oil and this information can be used to locate and potentially isolate the problem to a certain reservoir. Also, methods were developed to design suitable low dose naphthenate inhibitors. As these inhibitors are field tested, monitoring is required to ensure the product is performing most efficiently. In cases of tight emulsions however, this is less difficult as the oil dehydration and water quality is affected instantly. Methods were developed to allow monitoring of the calcium naphthenate deposition in field trails, thus allow trending and evaluation of the chemicals performance. After detailed analyses and discussions of the developed methods, a North Sea case history is presented reviewing several years of treating

  17. Violence associated with combat-related posttraumatic stress disorder: The importance of anger.

    Science.gov (United States)

    Novaco, Raymond W; Chemtob, Claude M

    2015-09-01

    The importance of anger with regard to violence among veterans with combat-related PTSD has received little attention. We previously proposed that in PTSD the activation of threat-related cognitive networks strongly potentiates anger in a positive feedback loop and that inhibitory controls on aggression can be overridden when PTSD and anger activation are conjoined. We predicted that violence would be intensified when combat-related PTSD was conjoined with anger. We used the National Vietnam Veterans Readjustment Study (NVVRS) public use data set, selecting the male combat theater veterans, which entailed 1,200 from the main survey (Study 1) and 259 from the clinical interview component (Study 2). Anger indices were constructed from NVVRS variables. PTSD was assessed by continuous symptom scores and by clinical diagnostic measures. Conjoined anger and PTSD was associated with greatly increased violence. PTSD was not associated with violence in the absence of anger. This result was obtained using alternative measures of PTSD and of anger in both the main survey and the clinical interview component. These findings call for reconceptualizing the association of PTSD and violence. Concerted attention should be given to anger as a risk factor for violence in the assessment and treatment of combat-related PTSD, and as an important portal of entry for treatment. (c) 2015 APA, all rights reserved).

  18. An analysis of psychotropic drug sales. Increasing sales of selective serotonin reuptake inhibitors are closely related to number of products.

    Science.gov (United States)

    Nielsen, Margrethe; Gøtzsche, Peter

    2011-01-01

    Prescribing of selective serotonin reuptake inhibitors (SSRIs) has increased dramatically. To compare the sales of benzodiazepines and SSRIs within the primary care sector in Denmark and relate changes in usage to number of indications and products on the market. We used data from various sources to establish the sales curves of psychotropic drugs in the period 1970 to 2007, based on the Anatomic Therapeutic Classification system and Defined Daily Doses. Fluctuations in sales of psychotropic drugs that cannot be explained by disease prevalence were caused by changes in sales of the benzodiazepines and SSRIs. We found a decline in the sales of benzodiazepines after a peak in 1986, likely due to the recognition that they cause dependence. From a low level in 1992, we found that the sales of SSRIs increased almost linearly by a factor of 18, up to 44 DDD per 1000 inhabitants, which was closely related to the number of products on the market that increased by a factor of 16. Sales of antidepressant drugs are mainly determined by market availability of products indicating that marketing pressures are playing an important role. Thus the current level of use of SSRIs may not be evidence-based, which is supported by studies showing that the effect of SSRIs has been overestimated.

  19. Relational Reasoning about Numbers and Operations--Foundation for Calculation Strategy Use in Multi-Digit Multiplication and Division

    Science.gov (United States)

    Schulz, Andreas

    2018-01-01

    Theoretical analysis of whole number-based calculation strategies and digit-based algorithms for multi-digit multiplication and division reveals that strategy use includes two kinds of reasoning: reasoning about the relations between numbers and reasoning about the relations between operations. In contrast, algorithms aim to reduce the necessary…

  20. The relative importance of different perceptual-cognitive skills during anticipation.

    Science.gov (United States)

    North, Jamie S; Hope, Ed; Williams, A Mark

    2016-10-01

    We examined whether anticipation is underpinned by perceiving structured patterns or postural cues and whether the relative importance of these processes varied as a function of task constraints. Skilled and less-skilled soccer players completed anticipation paradigms in video-film and point light display (PLD) format. Skilled players anticipated more accurately regardless of display condition, indicating that both perception of structured patterns between players and postural cues contribute to anticipation. However, the Skill×Display interaction showed skilled players' advantage was enhanced in the video-film condition, suggesting that they make better use of postural cues when available during anticipation. We also examined anticipation as a function of proximity to the ball. When participants were near the ball, anticipation was more accurate for video-film than PLD clips, whereas when the ball was far away there was no difference between viewing conditions. Perceiving advance postural cues appears more important than structured patterns when the ball is closer to the observer, whereas the reverse is true when the ball is far away. Various perceptual-cognitive skills contribute to anticipation with the relative importance of perceiving structured patterns and advance postural cues being determined by task constraints and the availability of perceptual information. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Towards a risk map of malaria for Sri Lanka: the importance of house location relative to vector breeding sites

    DEFF Research Database (Denmark)

    Van Der Hoek, Wim; Konradsen, Flemming; Amerasinghe, Priyanie H

    2003-01-01

    of house location relative to vector breeding sites for the occurrence of malaria in order to assess the usefulness of this parameter in future malaria risk maps. Such risk maps could be important tools for planning efficient malaria control measures. METHODS: In a group of seven villages in north central......BACKGROUND: In Sri Lanka, the major malaria vector Anopheles culicifacies breeds in pools formed in streams and river beds and it is likely that people living close to such breeding sites are at higher risk of malaria than people living further away. This study was done to quantify the importance...... Sri Lanka, malaria cases were compared with community controls for distance from house to breeding sites and a number of other variables, including type of housing construction and use of anti-mosquito measures. The presence of An. culicifacies in bedrooms was determined by indoor insecticide spray...

  2. Relative importance of natural and anthropogenic factors influencing karst rocky desertification

    Science.gov (United States)

    Xu, Erqi; Zhang, Hongqi

    2017-04-01

    As the most severe ecological issue in southwest China, karst rocky desertification (KRD) has both threatened and constrained regional sustainable development. Comprehensively understanding the relationship between the evolution of KRD and relevant driving data would provide more information to combat KRD in such complex karst environments. Past studies have been limited in quantifying the relative importance of driving factors influencing fine-scale KRD evolution, and have also lacked insight into their interactive impacts. To address these issues, we have used geographical information system techniques and a geographical detector model to explore the spatial consistency of driving factors and their interactions in relation to the evolution of KRD. Changshun County in China was selected as a representative area for the study. Nine relevant driving factors, including both natural and anthropogenic factors, were studied in regard to their relationships with KRD transformation between 2000 and 2010. Our results demonstrate the relative importance of driving data in influencing the improvement and deterioration of KRD. Lithology, soil type and road influence are identified as the leading factors. Interestingly, to our study at least, there is no significant difference between the impacts of natural and anthropogenic factors influencing KRD improvement, and even natural factors have a higher impact on KRD deterioration. Factors were found to enhance the influence of each other for KRD transformation. In particular, the results show a non-linearly enhanced effect between driving factors, which significantly aggravates KRD. New information found in our study helps to effectively control and restore areas afflicted by KRD.

  3. Important characteristics of an entrepreneur in relation to risk taking: Czech Republic case study

    Directory of Open Access Journals (Sweden)

    Ludmila Kozubíková

    2017-10-01

    Full Text Available New businesses arising at the market usually operate in the sector of small and medium-sized enterprises and account for a significant part of the whole global economy. Not only the success of a start-up company, but also its sequel within the SME sector are significantly influenced by entrepreneur's personality. The aim of this article is to explore the attitude to financial risk in relation to sociodemographic characteristics (gender, education, age and the most important personality traits of entrepreneurs (risk-taking, decisiveness, optimism. We have analyzed the data collected from 1141 respondents during 2015 in 14 regions of Czech Republic. Empirical results of our paper show that the researched entrepreneurs rather can't manage financial risks in their firms regardless their gender, education, age or personality traits. Most entrepreneurs consider the importance of financial risk to increase during the crisis period. These opinions differed in relation to age, gender and such personality traits as "decisiveness" and "optimism". The results also show that the entrepreneurs try to minimise the financial risk through building-up reserves in relation to such qualities as "risk-taking" and "decisiveness" in comparison to a rather negative attitude to "optimism".

  4. Environment and Spatial Influences on Aquatic Insect Communities in Cerrado Streams: the Relative Importance of Conductivity, Altitude, and Conservation Areas.

    Science.gov (United States)

    Godoy, B S; Queiroz, L L; Lodi, S; Oliveira, L G

    2017-04-01

    The aquatic insect community is an important element for stream functionality and diversity, but the effects of altitude and conservation areas on the aquatic insect community have been poorly explored in neotropical ecozone. The lack of studies about the relative importance of space and environment on community structure is another obstacle within aquatic insect ecology, which precludes the inclusion of these studies in more current frameworks, like the metacommunity dynamics. We evaluated the relationship between the aquatic insect community structure at 19 streams in the Brazilian Cerrado and spatial and environmental variables, namely geographical distance among sites, stream altitude, chemical variables, and environmental protection areas. We partitioned the variance explained by spatial and environmental components using a partial redundancy analysis. The environment exhibited a strong spatial structure for abundance and number of genera, increasing these community parameters with elevated water conductivity. Only community composition had a large unexplained portion of variance, with a small portion constrained by environmental (altitude and conductivity) and spatial factors. A relevant point in the result was the streams with high conductivity were located outside of the conservation areas. These results suggest that the relationship between number of genera and abundance with environmental conditions is always associated with spatial configuration of streams. Our study shows that altitude is an important determinant of community structure, as it exerts indirect influences, and electrical conductivity directly determines community composition, and that some national parks may be inefficient in maintaining the diversity of aquatic insects in the Cerrado region.

  5. Relative Importance and Knowledge Distribution of Medicinal Plants in a Kichwa Community in the Ecuadorian Amazon

    Directory of Open Access Journals (Sweden)

    Brian Joseph Doyle

    2017-01-01

    Full Text Available Traditional knowledge, such as knowledge of the use of plants as medicine, influences how indigenous people manage forest resources. Gender and age-associated differences in traditional knowledge may impact forest resource management because of the traditional division of labor. We interviewed 18 men and 18 women between 9 and 74 years old in San José de Payamino, an indigenous community of the Kichwa ethnicity in the Ecuadorian Amazon, to determine if there are gender or age-associated differences in medicinal plant knowledge among the Payamino people and to identify the most important species from a sample of medicinal plants. Individuals were interviewed using a tablet that displayed images of 34 plants, which had been cited by traditional healers in the community. Quantitative analysis provided insight into the relative importance of plants in the sample as well as the distribution of medicinal plant knowledge among members of the community. The most important plants were Tradescantia zanonia and Monolena primuliflora. These plants should be considered candidates for further investigation. There was a positive correlation between age and knowledge of medicinal plants, but no significant difference between genders. Our results suggest that an interview method that relies on digital images can reveal differences in the importance of medicinal plants as well as provide insight into the distribution of traditional medical knowledge. While men and women are likely to manage forest resources similarly, younger members of the community may not have the same regard for forest resources as their elder counterparts.

  6. “Counterterrorism Bookshelf” – 20 Important Books on Terrorism & Counterterrorism Related Subjects

    Directory of Open Access Journals (Sweden)

    Joshua Sinai

    2013-12-01

    Full Text Available This review column is the first in a series of columns that will provide a selective listing of important books by leading publishers on terrorism and counterterrorism-related subjects. The listings of publishers and their books are arranged in alphabetical order by publishers’ names, with their imprints included in their particular section. Within each section, the books are listed in alphabetical order, according to the lead author’s last name. Although most of the reviewed books are current, a few were published within the last several years, but are still considered to be important. Future columns will review books by publishers such as CRC Press, Hurst, Oxford University Press, Routledge, Stanford University Press, Springer, and University of Chicago Press.

  7. The Relative Importance of Language in Guiding Social Preferences Through Development.

    Science.gov (United States)

    Esseily, Rana; Somogyi, Eszter; Guellai, Bahia

    2016-01-01

    In this paper, we review evidence from infants, toddlers, and preschoolers to tackle the question of how individuals orient preferences and actions toward social partners and how these preferences change over development. We aim at emphasizing the importance of language in guiding categorization relatively to other cues such as age, race and gender. We discuss the importance of language as part of a communication system that orients infants and older children's attention toward relevant information in their environment and toward affiliated social partners who are potential sources of knowledge. We argue that other cues (visually perceptible features) are less reliable in informing individuals whether others share a common knowledge and whether they can be source of information.

  8. The relative importance of language in guiding social preferences through development

    Directory of Open Access Journals (Sweden)

    Rana Esseily

    2016-10-01

    Full Text Available In this paper, we review evidence from infants, toddlers and preschoolers to tackle the ques-tion of how individuals orient preferences and actions towards social partners and how these preferences change over development. We aim at emphasizing the importance of language in guiding categorization relatively to other cues such as age, race and gender. We discuss the importance of language as part of a communication system that orients infants and older chil-dren’s attention towards relevant information in their environment and towards affiliated so-cial partners who are potential sources of knowledge. We argue that other cues (visually per-ceptible features are less reliable in informing individuals whether others share a common knowledge and whether they can be source of information.

  9. Examination of the relative importance of hospital employment in non-metropolitan counties using location quotients.

    Science.gov (United States)

    Smith, Jon L

    2013-01-01

    The US Health Care and Social Services sector (North American Industrial Classification System 'sector 62') has become an extremely important component of the nation's economy, employing approximately 18 million workers and generating almost $753 billion in annual payrolls. At the county level, the health care and social services sector is typically the largest or second largest employer. Hospital employment is often the largest component of the sector's total employment. Hospital employment is particularly important to non-metropolitan or rural communities. A high quality healthcare sector serves to promote economic development and attract new businesses and to provide stability in economic downturns. The purpose of this study was to examine the intensity of hospital employment in rural counties relative to the nation as a whole using location quotients and to draw conclusions regarding how potential changes in Medicare and Medicaid might affect rural populations. Estimates for county-level hospital employment are not commonly available. Estimates of county-level hospital employment were therefore generated for all counties in the USA the Census Bureau's County Business Pattern Data for 2010. These estimates were used to generate location quotients for each county which were combined with demographic data to generate a profile of factors that are related to the magnitude of location quotients. The results were then used to draw inferences regarding the possible impact of the Patient Protection and Affordable Care Act 2010 (ACA) and the possible imposition of aspects of the Budget Control Act 2011 (BCA). Although a very high percentage of rural counties contain medically underserved areas, an examination of location quotients indicates that the percentage of the county workforce employed by hospitals in the most rural counties tends to be higher than for the nation as a whole, a counterintuitive finding. Further, when location quotients are regressed upon data

  10. On the relative importance of audio and video in the presence of packet losses

    DEFF Research Database (Denmark)

    Korhonen, Jari; Reiter, Ulrich; Myakotnykh, Eugene

    2010-01-01

    In streaming applications, unequal protection of audio and video tracks may be necessary to maintain the optimal perceived overall quality. For this purpose, the application should be aware of the relative importance of audio and video in an audiovisual sequence. In this paper, we propose...... a subjective test arrangement for finding the optimal tradeoff between subjective audio and video qualities in situations when it is not possible to have perfect quality for both modalities concurrently. Our results show that content poses a significant impact on the preferred compromise between audio...... and video quality, but also that the currently used classification criteria for content are not sufficient to predict the users’ preference...

  11. Relative importance of food and water pathways in the bio-accumulation of zinc

    International Nuclear Information System (INIS)

    Renfro, W.C.; Fowler, S.W.; Heyraud, M.; LaRosa, J.

    1974-01-01

    The relative importance of the food versus water pathway as a source of radionuclides to aquatic organisms is studied through laboratory experiments allowing groups of animals to accumulate 65 Zn from the two pathways simultaneously in the same simulated ecosystem. Mean whole body concentration factors of 65 Zn and stable zinc in shrimp, crab, fish and mussels are recorded. In shrimp and fish accumulation of 65 Zn through the food pathway is reported more than the water pathway though fluctuations in food quality and feeding rates could alter zinc absorption kinetics

  12. Measuring the importance of oil-related revenues in total fiscal income for Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Reyes-Loya, Manuel Lorenzo; Blanco, Lorenzo [Facultad de Economia, Universidad Autonoma de Nuevo Leon, Loma Redonda 1515 Pte., Col. Loma Larga, C.P. 64710, Monterrey, Nuevo Leon (Mexico)

    2008-09-15

    Revenues from oil exports are an important part of government budgets in Mexico. A time-series analysis is conducted using monthly data from 1990 to 2005 examining three different specifications to determine how international oil price fluctuations and government income generated from oil exports influence fiscal policy in Mexico. The behavior of government spending and taxation is consistent with the spend-tax hypothesis. The results show that there is an inverse relationship between oil-related revenues and tax revenue from non-oil sources. Fiscal policy reform is urgently needed in order to improve tax collection as oil reserves in Mexico become more and more depleted. (author)

  13. Measuring the importance of oil-related revenues in total fiscal income for Mexico

    International Nuclear Information System (INIS)

    Reyes-Loya, Manuel Lorenzo; Blanco, Lorenzo

    2008-01-01

    Revenues from oil exports are an important part of government budgets in Mexico. A time-series analysis is conducted using monthly data from 1990 to 2005 examining three different specifications to determine how international oil price fluctuations and government income generated from oil exports influence fiscal policy in Mexico. The behavior of government spending and taxation is consistent with the spend-tax hypothesis. The results show that there is an inverse relationship between oil-related revenues and tax revenue from non-oil sources. Fiscal policy reform is urgently needed in order to improve tax collection as oil reserves in Mexico become more and more depleted. (author)

  14. The relative importance of relativistic induced interactions in the beta decay of 170Tm

    International Nuclear Information System (INIS)

    Bogdan, D.; Cristu, M.I.; Holan, S.; Faessler, A.

    1982-09-01

    The log ft-values, the spectrum shape functions, and the beta-gamma angular correlation coefficients of the 170 Tm beta decay are computed in the framework of relativistic formfactor formalism using asymmetric rotor model wavefunctions. Main vector and axial vector hadron currents being strongly hindered, the relative importance of induced interaction matrix elements is accurately estimated. Good agreement with experiment is obtained for the beta decay observables when the main induced interaction terms were taken into account. The contribution of the pseudoscalar term was found insignificant. (authors)

  15. Trust-Building in Electronic Markets: Relative Importance and Interaction Effects of Trust-Building Mechanisms

    Science.gov (United States)

    Tams, Stefan

    We examine the relative and complementary effectiveness of trust-building strategies in online environments. While prior research has examined various antecedents to trust, we investigated two trust-building mechanisms more in depth: Web site trust and vendor reputation. We tried to understand the relative effectiveness of these two important mechanisms to provide online businesses with a clear recommendation of how to establish trust in an effective and efficient manner. Drawing from the literature on trust, we proposed vendor reputation to be more effective than Web site trust. Moreover, we examined a potential complementary effect of these mechanisms so as to provide online businesses with a deeper understanding of how to derive superior trust. We hypothesize a small such effect. The study proposes a laboratory experiment to test the model.

  16. Relation of Different Type Love-Shida Numbers Determined with the Use of Time-Varying Incremental Gravitational Potential

    Science.gov (United States)

    Varga, Peter; Grafarend, Erik; Engels, Johannes

    2017-03-01

    There are different equations to describe relations between different classes of Love-Shida numbers. In this study with the use of the time-varying gravitational potential an integral relation was obtained which connects tidal Love-Shida numbers (h, l, k), load numbers (h', l', k'), potential free Love-Shida numbers generated by normal (h″, l″, k″) and horizontal (h‴, l‴, k‴) stresses. The equations obtained in frame of present study is the only one which - holds for every type of Love-Shida numbers, - describes a relationship not between different, but the same type of Love-Shida numbers, - does not follow from the sixth-order differential equation system of motion usually applied to calculate the Love-Shida numbers.

  17. The number of taste buds is related to bitter taste sensitivity in layer and broiler chickens.

    Science.gov (United States)

    Kudo, Ken-ichi; Shiraishi, Jun-ichi; Nishimura, Shotaro; Bungo, Takashi; Tabata, Shoji

    2010-04-01

    The relationship between taste sensitivity and the number of taste buds using a bitter tastant, quinine hydrochloride, was investigated in White Leghorn, Rhode Island Red, and broiler chickens. The White Leghorn and Rhode Island Red strains were able to perceive 2.0 mmol/L quinine hydrochloride, but the taste sensitivity of Rhode Island Red chickens was higher than that of White Leghorn chickens. Broiler chickens perceived 0.5 mmol/L quinine hydrochloride. The number of taste buds in the White Leghorn strain was the lowest, then the Rhode Island Red strain, with the number of taste buds highest in the broiler chickens. The number of taste buds was well correlated with bitter taste sensitivity. Therefore, we suggest that the number of taste buds is a vital factor in the perception of bitter taste and may be useful in selecting appropriate feeds for chickens.

  18. The importance of family relations for cannabis users: the case of serbian adolescents.

    Science.gov (United States)

    Terzic Supic, Zorica; Santric Milicevic, Milena; Sbutega, Isidora; Vasic, Vladimir

    2013-01-01

    Adolescence is transitional stage of physical and mental human development occuring between childhood and adult life. Social interactions and environmental factors together are important predictors of adolescent cannabis use. This study aimed to examine the relationship between the social determinants and adolescents behavior with cannabis consumption. A cross sectional study as part of the European School Survey Project on Alcohol and other Drugs was conducted among 6.150 adolescents aged 16 years in three regions of Serbia, and three types of schools (gymnasium, vocational - professional, and vocational - handicraft) during May - June 2008. A multivariate logistic regression analysis was carried out to obtain adjusted odds ratios with 95% confidence intervals in which the dependent variable was cannabis consumption non-user and user. Among 6.7% of adolescents who had tried cannabis at least one in their lives, boys were more involved in cannabis use than girls, especially boys from gymnasium school. Well off family, lower education of mother, worse relations with parents were significantly associated with cannabis use (P related to cannabis use (P study confirmed the importance of family relationship development. Drug use preventive programmes should include building interpersonal trust in a family lifecycle and school culture.

  19. Relative importance of methylotrophic methanogenesis in sediments of the Western Mediterranean Sea

    Science.gov (United States)

    Zhuang, Guang-Chao; Heuer, Verena B.; Lazar, Cassandre S.; Goldhammer, Tobias; Wendt, Jenny; Samarkin, Vladimir A.; Elvert, Marcus; Teske, Andreas P.; Joye, Samantha B.; Hinrichs, Kai-Uwe

    2018-03-01

    Microbial production of methane is an important terminal metabolic process during organic matter degradation in marine sediments. It is generally acknowledged that hydrogenotrophic and acetoclastic methanogenesis constitute the dominant pathways of methane production; the importance of methanogenesis from methylated compounds remains poorly understood. We conducted various biogeochemical and molecular genetic analyses to characterize substrate availability, rates of methanogenesis, and methanogen community composition, and further evaluated the contribution of different substrates and pathways for methane production in deltaic surface and subsurface sediments of the Western Mediterranean Sea. Major substrates representing three methanogenic pathways, including H2, acetate, and methanol, trimethylamine (TMA), and dimethylsulfide (DMS), were detected in the pore waters and sediments, and exhibited variability over depth and between sites. In accompanying incubation experiments, methanogenesis rates from various 14C labeled substrates varied as well, suggesting that environmental factors, such as sulfate concentration and organic matter quality, could significantly influence the relative importance of individual pathway. In particular, methylotrophic and hydrogenotrophic methanogenesis contributed to the presence of micromolar methane concentrations in the sulfate reduction zone, with methanogenesis from methanol accounting for up to 98% of the total methane production in the topmost surface sediment. In the sulfate-depleted zone, hydrogenotrophic methanogenesis was the dominant methanogenic pathway (67-98%), and enhanced methane production from acetate was observed in organic-rich sediment (up to 31%). Methyl coenzyme M reductase gene (mcrA) analysis revealed that the composition of methanogenic communities was generally consistent with the distribution of methanogenic activity from different substrates. This study provides the first quantitative assessment of

  20. Some properties of the Catalan-Qi function related to the Catalan numbers.

    Science.gov (United States)

    Qi, Feng; Mahmoud, Mansour; Shi, Xiao-Ting; Liu, Fang-Fang

    2016-01-01

    In the paper, the authors find some properties of the Catalan numbers, the Catalan function, and the Catalan-Qi function which is a generalization of the Catalan numbers. Concretely speaking, the authors present a new expression, asymptotic expansions, integral representations, logarithmic convexity, complete monotonicity, minimality, logarithmically complete monotonicity, a generating function, and inequalities of the Catalan numbers, the Catalan function, and the Catalan-Qi function. As by-products, an exponential expansion and a double inequality for the ratio of two gamma functions are derived.

  1. Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics

    Directory of Open Access Journals (Sweden)

    Liu Melissa M

    2012-08-01

    Full Text Available Abstract Age-related macular degeneration (AMD is a complex and multifaceted disease involving contributions from both genetic and environmental influences. Previous work exploring the genetic contributions of AMD has implicated numerous genomic regions and a variety of candidate genes as modulators of AMD susceptibility. Nevertheless, much of this work has revolved around single-nucleotide polymorphisms (SNPs, and it is apparent that a significant portion of the heritability of AMD cannot be explained through these mechanisms. In this review, we consider the role of common variants, rare variants, copy number variations, epigenetics, microRNAs, and mitochondrial genetics in AMD. Copy number variations in regulators of complement activation genes (CFHR1 and CFHR3 and glutathione S transferase genes (GSTM1 and GSTT1 have been associated with AMD, and several additional loci have been identified as regions of potential interest but require further evaluation. MicroRNA dysregulation has been linked to the retinal pigment epithelium degeneration in geographic atrophy, ocular neovascularization, and oxidative stress, all of which are hallmarks in the pathogenesis of AMD. Certain mitochondrial DNA haplogroups and SNPs in mitochondrially encoded NADH dehydrogenase genes have also been associated with AMD. The role of these additional mechanisms remains only partly understood, but the importance of their further investigation is clear to elucidate more completely the genetic basis of AMD.

  2. The relative importance of avoidance and restoration-oriented stressors for grief and depression in bereaved parents.

    Science.gov (United States)

    Harper, Mairi; O'Connor, Rory C; O'Carroll, Ronan E

    2015-01-01

    Previous research has identified a number of individual risk factors for parental bereavement including the sex of the parent, the sex of the child, avoidance-focussed coping style and time since death. These factors emerged from research where variables were tested univariately and their relative importance is currently unknown. The current research, therefore, aims to investigate which risk factors are important, multivariately, for the outcomes of grief and depression in parents following the death of their child. Psychosocial measures were completed by 106 bereaved parents four years post-loss, recruited from death records in Scotland. The cause of the child's death included long-term illness and stillbirths as well as sudden and violent deaths. In multivariate regression analyses, depression was predicted by higher avoidance-focussed coping and higher number of restoration-oriented stressors such as relationship difficulties, problems at work and financial issues. Grief was predicted by higher avoidance, restoration stressors and level of continuing bonds. The present study adds to the knowledge about the phenomenon of parental bereavement with participants recruited directly from death records rather than through support, clinical or obituary sources. Factors previously found to be associated with outcomes when tested univariately such as sudden, violent death or sex of the parent were not significant when tested multivariately. This study highlights that different vulnerability factors exist for grief and depression in bereaved parents.

  3. Health-related quality of life and risk factor control: the importance of educational level in prevention of cardiovascular diseases.

    Science.gov (United States)

    Ose, Dominik; Rochon, Justine; Campbell, Stephen M; Wensing, Michel; Freund, Tobias; van Lieshout, Jan; Längst, Gerda; Szecsenyi, Joachim; Ludt, Sabine

    2014-08-01

    This study aimed to describe and to analyse the importance of educational level for controlled risk factors and health-related quality of life (HRQoL). This observational study was conducted in nine European countries (5632 patients in 249 practices). We compared patients with a low level of education (up to 9 years) with patients with a high level of education (>9 years), with regard to controlled cardiovascular disease risk factors and HRQoL. A multilevel approach was used for statistical analysis. Patients with a low level of education were older (P education, female gender, living as single, patient group (coronary heart disease patients) and the number of other conditions were negatively associated with HRQoL. A higher sum of controlled risk factors were positively associated with higher HRQoL in the whole sample (r = 0.0086, P educational-level groups (r = 0.0075, P = 0.038 in the low-level group and r = 0.0082, P = 0.001 in the high-level group). Patients with a lower educational level were more often females, singles, had a higher number of other conditions, a higher number of uncontrolled risk factors and a lower HRQoL. However, the higher the control of risk factors was, the higher the HRQoL was overall as well as in both educational-level groups. © The Author 2013. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  4. The Importance of Augustin Hallerstein for Cultural and Political Relations with China and Korea

    Directory of Open Access Journals (Sweden)

    Mitja SAJE

    2015-12-01

    Full Text Available Since symbols of early cultural relations between Europe and East Asia are important, we are striving to restore the image of Augustin Hallerstein (1703–1774 in China and earn his legacy its appropriate position in the history of the Qing dynasty next to other great Jesuits like Adam Shall von Bell (1591–1666, Ferdinand Verbiest (1623–1688, or Ignatius Kogler (1680–1746. A two-year EU project made possible the publication of a monograph in English, which was translated into Chinese and published in China in February 2015. Wider popularization of his achievements should be beneficial to Slovenia as well as to China, where he did his work. Such common heroes of the past could often be used to promote better understanding and cooperation between China and Slovenia. Through strong connections with Korean scholars he gained a high reputation in Korea as well.

  5. The relative importance of information sources in consumers' choice of hospitals.

    Science.gov (United States)

    Gooding, S K

    1995-01-01

    The research presented focuses on an examination of the relative importance of word-of-mouth, expert opinion, external communication, and past experience in the context of hospital choice. Past research has examined the effect of each individually and various combinations of the four sources, but not all four simultaneously. Results of the present study suggest that past experience plays a greater role in hospital choice than other information sources, including expert opinion. The strength of word-of-mouth as a source of information is also verified. The implications of this research include the following: (1) health care researchers need to incorporate word-of-mouth when investigating informations sources, and (2) local hospitals need to be aware of "negative perceptions" and strive for consumer satisfaction. Health care delivery systems incorporating consumer-based choice render these findings especially valuable as researchers and practitioners address the challenges that these evolving systems will bring.

  6. On the Relative Importance of Corporate Working Capital Determinants: Findings from the EU Countries

    Directory of Open Access Journals (Sweden)

    Julia Koralun-Bereźnicka

    2014-12-01

    Full Text Available The corporate finance literature traditionally abounds in both theoretical discussion and empirical research concerning financing and long-term investment decisions. Managing short-term resources appears to be a much less remarkable issue, despite this resource’s significant share of a firm’s balance sheet and the time and effort required to manage the current assets and liabilities. This article provides insights into the relative importance of the selected working capital determinants from the European Union perspective. The determinants considered in the study include both external and internal factors, specifically the country in which a company operates, its industrial classification and the firm size. Using more than 10,000 aggregated observations from a sample of firms from 13 industries, 9 countries and 3 group sizes, covering the period 2000-2009, the findings provide evidence that corporate working capital is most affected by country-specific factors, followed by industrial factors and firm size.

  7. The Relative Importance of the Service Sector in the Mexican Economy: A Time Series Analysis

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Flores

    2014-01-01

    Full Text Available We conduct a study of the secondary and tertiary sectors with the goal of highlighting the relative im-portance of services in the Mexican economy. We consider a time series analysis approach designed to identify the stochastic nature of the series, as well as to define their long-run and-short run relationships with Gross Domestic Product (GDP. The results of cointegration tests suggest that, for the most part, activities in the secondary and tertiary sectors share a common trend with GDP. Interestingly, the long-run elasticities of GDP with respect to services are on average larger than those with respect to secondary activities. Common cycle tests results identify the existence of common cycles between GDP and the disaggregated sectors, as well as with manufacturing, commerce, real estate and transportation. In this case, the short-run elasticities of secondary activities are on average larger than those corresponding to services.

  8. Partitioning the Relative Importance of Phylogeny and Environmental Conditions on Phytoplankton Fatty Acids

    Science.gov (United States)

    Galloway, Aaron W. E.; Winder, Monika

    2015-01-01

    Essential fatty acids (EFA), which are primarily generated by phytoplankton, limit growth and reproduction in diverse heterotrophs. The biochemical composition of phytoplankton is well-known to be governed both by phylogeny and environmental conditions. Nutrients, light, salinity, and temperature all affect both phytoplankton growth and fatty acid composition. However, the relative importance of taxonomy and environment on algal fatty acid content has yet to be comparatively quantified, thus inhibiting predictions of changes to phytoplankton food quality in response to global environmental change. We compiled 1145 published marine and freshwater phytoplankton fatty acid profiles, consisting of 208 species from six major taxonomic groups, cultured in a wide range of environmental conditions, and used a multivariate distance-based linear model to quantify the total variation explained by each variable. Our results show that taxonomic group accounts for 3-4 times more variation in phytoplankton fatty acids than the most important growth condition variables. The results underscore that environmental conditions clearly affect phytoplankton fatty acid profiles, but also show that conditions account for relatively low variation compared to phylogeny. This suggests that the underlying mechanism determining basal food quality in aquatic habitats is primarily phytoplankton community composition, and allows for prediction of environmental-scale EFA dynamics based on phytoplankton community data. We used the compiled dataset to calculate seasonal dynamics of long-chain EFA (LCEFA; ≥C20 ɷ-3 and ɷ-6 polyunsaturated fatty acid) concentrations and ɷ-3:ɷ-6 EFA ratios in Lake Washington using a multi-decadal phytoplankton community time series. These analyses quantify temporal dynamics of algal-derived LCEFA and food quality in a freshwater ecosystem that has undergone large community changes as a result of shifting resource management practices, highlighting diatoms

  9. Expected number of asbestos-related lung cancers in the Netherlands in the next two decades : a comparison of methods

    NARCIS (Netherlands)

    Van der Bij, Sjoukje; Vermeulen, Roel C H; Portengen, Lützen; Moons, Karel G M; Koffijberg, Hendrik

    2016-01-01

    OBJECTIVES: Exposure to asbestos fibres increases the risk of mesothelioma and lung cancer. Although the vast majority of mesothelioma cases are caused by asbestos exposure, the number of asbestos-related lung cancers is less clear. This number cannot be determined directly as lung cancer causes are

  10. Relative importance of nitrate and sulfate aerosol production mechanisms in urban atmospheres

    International Nuclear Information System (INIS)

    Middleton, P.; Kiang, C.S.

    1979-01-01

    The relative importance of the various sulfate and nitrate aerosol production mechanisms is calculated for different atmospheric conditions. The calculation scheme used to determine the rates of nitrate and sulfate production, based on the concept that vapor transfer to the aerosols and nitrate and sulfate formation within the aerosols are coupled kinetic processes, considers sulfate formation by ozone and hydrogen peroxide oxidation and catalytic oxidation in the presence of soot, iron and manganese of sulfite solutions and sulfuric acid condensation and nitrate formation by the liquid-phase oxidation of dissolved nitrogen oxides for different initial gas concentrations and particle compositions and sizes. It is found that sulfate production is higher under daytime conditions, primarily proceeding by mechanisms involving sulfuric acid and hydrogen peroxide, while at night oxidation processes on the surface of the aerosol film are more important. Nitrate tends to decrease nighttime sulfate production due to an increase in aerosol acidity and nitrate production is found to be higher under nighttime conditions and in the winter

  11. Virulence factors of Escherichia coli in relation to the importance of vaccination in pigs

    Directory of Open Access Journals (Sweden)

    Daniele Araujo Pereira

    2016-08-01

    Full Text Available ABSTRACT: Enterotoxigenic Escherichia coli (ETEC is the major cause of diarrhea in newborn and weaned pigs. Bacteria adhesion to the host cell is considered a specific phenomenon among fimbrial and non-fimbrial adhesins with their respective receptors on enterocytes. Enteric disorders are related with the fimbriae F4 (K88, F5 (K99, F6 (987P, F41, and F18. In addition to ETEC, another category of E. coli , porcine pathogenic E. coli (PEPEC,can cause diarrhea in pigs; it produces the porcine attaching and effacing-associated (Paa adhesin in, which is capable to cause a typical lesion known as an attaching and effacing (A/E lesion. Immunization of sows with adhesin is important to stimulate the production of antibodies and their subsequent transfer to piglets through colostrum. The aim of this paper is to illustrate the main impacts of enteric diseases caused by E. coli in swine production and to highlight the importance of continuing research on this bacterium to improve disease prevention through vaccination.

  12. Remote Sensing of plant functional types: Relative importance of biochemical and structural plant traits

    Science.gov (United States)

    Kattenborn, Teja; Schmidtlein, Sebastian

    2017-04-01

    Monitoring ecosystems is a key priority in order to understand vegetation patterns, underlying resource cycles and changes their off. Driven by biotic and abiotic factors, plant species within an ecosystem are likely to share similar structural, physiological or phenological traits and can therefore be grouped into plant functional types (PFT). It can be assumed that plants which share similar traits also share similar optical characteristics. Therefore optical remote sensing was identified as a valuable tool for differentiating PFT. Although several authors list structural and biochemical plant traits which are important for differentiating PFT using hyperspectral remote sensing, there is no quantitative or qualitative information on the relative importance of these traits. Thus, little is known about the explicit role of plant traits for an optical discrimination of PFT. One of the main reasons for this is that various optical traits affect the same wavelength regions and it is therefore difficult to isolate the discriminative power of a single trait. A way to determine the effect of single plant traits on the optical reflectance of plant canopies is given by radiative transfer models. The most established radiative transfer model is PROSAIL, which incorporates biochemical and structural plant traits, such as pigment contents or leaf area index. In the present study 25 grassland species of different PFT were cultivated and traits relevant for PROSAIL were measured for the entire vegetation season of 2016. The information content of each trait for differentiating PFTs was determined by applying a Multi-response Permutation Procedure on the actual traits, as well as on simulated canopy spectra derived from PROSAIL. According to our results some traits, especially biochemical traits, show a weaker separability of PFT on a spectral level than compared to the actual trait measurements. Overall structural traits (leaf angle and leaf area index) are more important for

  13. Institutional delivery in rural India: the relative importance of accessibility and economic status.

    Science.gov (United States)

    Kesterton, Amy J; Cleland, John; Sloggett, Andy; Ronsmans, Carine

    2010-06-06

    Skilled attendance at delivery is an important indicator in monitoring progress towards Millennium Development Goal 5 to reduce the maternal mortality ratio by three quarters between 1990 and 2015. In addition to professional attention, it is important that mothers deliver their babies in an appropriate setting, where life saving equipment and hygienic conditions can also help reduce the risk of complications that may cause death or illness to mother and child. Over the past decade interest has grown in examining influences on care-seeking behavior and this study investigates the determinants of place of delivery in rural India, with a particular focus on assessing the relative importance of community access and economic status. A descriptive analysis of trends in place of delivery using data from two national representative sample surveys in 1992 and 1998 is followed by a two-level (child/mother and community) random-effects logistical regression model using the second survey to investigate the determinants. In this investigation of institutional care seeking for child birth in rural India, economic status emerges as a more crucial determinant than access. Economic status is also the strongest influence on the choice between a private-for-profit or public facility amongst institutional births. Greater availability of obstetric services will not alone solve the problem of low institutional delivery rates. This is particularly true for the use of private-for-profit institutions, in which the distance to services does not have a significant adjusted effect. In the light of these findings a focus on increasing demand for existing services seems the most rational action. In particular, financial constraints need to be addressed, and results support current trials of demand side financing in India.

  14. Beyond Precipitation: Physiographic Gradients Dictate the Relative Importance of Environmental Drivers on Savanna Vegetation

    Science.gov (United States)

    Campo-Bescós, Miguel A.; Muñoz-Carpena, Rafael; Kaplan, David A.; Southworth, Jane; Zhu, Likai; Waylen, Peter R.

    2013-01-01

    Background Understanding the drivers of large-scale vegetation change is critical to managing landscapes and key to predicting how projected climate and land use changes will affect regional vegetation patterns. This study aimed to improve our understanding of the role, magnitude and spatial distribution of the key environmental factors driving vegetation change in southern African savanna, and how they vary across physiographic gradients. Methodology/Principal Findings We applied Dynamic Factor Analysis (DFA), a multivariate times series dimension reduction technique to ten years of monthly remote sensing data (MODIS-derived normalized difference vegetation index, NDVI) and a suite of environmental covariates: precipitation, mean and maximum temperature, soil moisture, relative humidity, fire and potential evapotranspiration. Monthly NDVI was described by cyclic seasonal variation with distinct spatiotemporal patterns in different physiographic regions. Results support existing work emphasizing the importance of precipitation, soil moisture and fire on NDVI, but also reveal overlooked effects of temperature and evapotranspiration, particularly in regions with higher mean annual precipitation. Critically, spatial distributions of the weights of environmental covariates point to a transition in the importance of precipitation and soil moisture (strongest in grass-dominated regions with precipitation950 mm). Conclusions/Significance We quantified the combined spatiotemporal effects of an available suite of environmental drivers on NDVI across a large and diverse savanna region. The analysis supports known drivers of savanna vegetation but also uncovers important roles of temperature and evapotranspiration. Results highlight the utility of applying the DFA approach to remote sensing products for regional analyses of landscape change in the context of global environmental change. With the dramatic increase in global change research, this methodology augurs well for

  15. Microarray MAPH: accurate array-based detection of relative copy number in genomic DNA.

    Science.gov (United States)

    Gibbons, Brian; Datta, Parikkhit; Wu, Ying; Chan, Alan; Al Armour, John

    2006-06-30

    Current methods for measurement of copy number do not combine all the desirable qualities of convenience, throughput, economy, accuracy and resolution. In this study, to improve the throughput associated with Multiplex Amplifiable Probe Hybridisation (MAPH) we aimed to develop a modification based on the 3-Dimensional, Flow-Through Microarray Platform from PamGene International. In this new method, electrophoretic analysis of amplified products is replaced with photometric analysis of a probed oligonucleotide array. Copy number analysis of hybridised probes is based on a dual-label approach by comparing the intensity of Cy3-labelled MAPH probes amplified from test samples co-hybridised with similarly amplified Cy5-labelled reference MAPH probes. The key feature of using a hybridisation-based end point with MAPH is that discrimination of amplified probes is based on sequence and not fragment length. In this study we showed that microarray MAPH measurement of PMP22 gene dosage correlates well with PMP22 gene dosage determined by capillary MAPH and that copy number was accurately reported in analyses of DNA from 38 individuals, 12 of which were known to have Charcot-Marie-Tooth disease type 1A (CMT1A). Measurement of microarray-based endpoints for MAPH appears to be of comparable accuracy to electrophoretic methods, and holds the prospect of fully exploiting the potential multiplicity of MAPH. The technology has the potential to simplify copy number assays for genes with a large number of exons, or of expanded sets of probes from dispersed genomic locations.

  16. Suppression of lymphocyte proliferation by marijuana components is related to cell number and cell source

    International Nuclear Information System (INIS)

    Klein, T.; Pross, S.; Newton, C.; Friedman, H.

    1986-01-01

    Conflicting reports have appeared concerning the effect of marijuana components on immune responsiveness. The authors have observed that the effect of cannabinoids on lymphocyte proliferation varied with both the concentration of the drug and the mitogen used. They now report that at a constant concentration of drug, the cannabinoid effect varied from no effect to suppression depending upon the number of cells in culture and the organ source of the cells. Dispersed cell suspensions of mouse lymph node, spleen, and thymus were prepared and cultured at varying cell numbers with either delta-9-tetrahydrocannabinol or 11-hydroxy-delta-9-tetrahydrocannabinol and various mitogens. Lymphocyte proliferation was analyzed by 3 H-thymidine incorporation. T-lymphocyte mitogen responses in cultures containing high cell numbers were unaffected by the cannabinoids but as cell numbers were reduced a suppression of the response was observed. Furthermore, thymus cells were considerably more susceptible to cannabinoid suppression than cells from either lymph node or spleen. These results suggest that certain lymphocyte subpopulations are more sensitive to cannabinoid suppression and that in addition to drug concentration other variables such as cell number and cell source must be considered when analyzing cannabinoid effects

  17. Orphan Drug Pricing: An Original Exponential Model Relating Price to the Number of Patients

    Directory of Open Access Journals (Sweden)

    Andrea Messori

    2016-10-01

    Full Text Available In managing drug prices at the national level, orphan drugs represent a special case because the price of these agents is higher than that determined according to value-based principles. A common practice is to set the orphan drug price in an inverse relationship with the number of patients, so that the price increases as the number of patients decreases. Determination of prices in this context generally has a purely empirical nature, but a theoretical basis would be needed. The present paper describes an original exponential model that manages the relationship between price and number of patients for orphan drugs. Three real examples are analysed in detail (eculizumab, bosentan, and a data set of 17 orphan drugs published in 2010. These analyses have been aimed at identifying some objective criteria to rationally inform this relationship between prices and patients and at converting these criteria into explicit quantitative rules.

  18. Relative Importance of Chemoautotrophy for Primary Production in a Light Exposed Marine Shallow Hydrothermal System

    Directory of Open Access Journals (Sweden)

    Gonzalo V. Gomez-Saez

    2017-04-01

    Full Text Available The unique geochemistry of marine shallow-water hydrothermal systems promotes the establishment of diverse microbial communities with a range of metabolic pathways. In contrast to deep-sea vents, shallow-water vents not only support chemosynthesis, but also phototrophic primary production due to the availability of light. However, comprehensive studies targeting the predominant biogeochemical processes are rare, and consequently a holistic understanding of the functioning of these ecosystems is currently lacking. To this end, we combined stable isotope probing of lipid biomarkers with an analysis of the bacterial communities to investigate if chemoautotrophy, in parallel to photoautotrophy, plays an important role in autotrophic carbon fixation and to identify the key players. The study was carried out at a marine shallow-water hydrothermal system located at 5 m water depth off Dominica Island (Lesser Antilles, characterized by up to 55°C warm hydrothermal fluids that contain high amounts of dissolved Fe2+. Analysis of the bacterial diversity revealed Anaerolineae of the Chloroflexi as the most abundant bacterial class. Furthermore, the presence of key players involved in iron cycling generally known from deep-sea hydrothermal vents (e.g., Zetaproteobacteria and Geothermobacter, supported the importance of iron-driven redox processes in this hydrothermal system. Uptake of 13C-bicarbonate into bacterial fatty acids under light and dark conditions revealed active photo- and chemoautotrophic communities, with chemoautotrophy accounting for up to 65% of the observed autotrophic carbon fixation. Relatively increased 13C-incorporation in the dark allowed the classification of aiC15:0, C15:0, and iC16:0 as potential lipid biomarkers for bacterial chemoautotrophy in this ecosystem. Highest total 13C-incorporation into fatty acids took place at the sediment surface, but chemosynthesis was found to be active down to 8 cm sediment depth. In conclusion

  19. The relative importance of physical and biological energy in landscape evolution

    Science.gov (United States)

    Turowski, J. M.; Schwanghart, W.

    2017-12-01

    Landscapes are formed by the interplay of uplift and geomorphic processes, including interacting and competing physical and biological processes. For example, roots re-inforce soil and thereby stabilize hillslopes and the canopy cover of the forest may mediate the impact of precipitation. Furthermore, plants and animals act as geomorphic agents, directly altering landscape response and dynamics by their actions: tree roots may crack rocks, thus changing subsurface water flows and exposing fresh material for denudation; fungi excrete acids that accelerate rates of chemical weathering, and burrowing animals displace soil and rocks while digging holes for shelter or in search of food. Energetically, landscapes can be viewed as open systems in which topography stores potential energy above a base level. Tectonic processes add energy to the system by uplift and mechanically altering rock properties. Especially in unvegetated regions, erosion and transport by wind can be an important geomorphic process. Advection of atmospheric moisture in high altitudes provides potential energy that is converted by water fluxes through catchments. At the same time, the conversion of solar energy through atmospheric and biological processes drives primary production of living organisms. If we accept that biota influence geomorphic processes, then what is their energetic contribution to landscape evolution relative to physical processes? Using two case studies, we demonstrate that all components of energy input are negligible apart from biological production, quantified by net primary productivity (NPP) and potential energy conversion by water that is placed high up in the landscape as rainfall and leaves it as runoff. Assuming that the former is representative for biological energy and the latter for physical energy, we propose that the ratio of these two values can be used as a proxy for the relative importance of biological and physical processes in landscape evolution. All necessary

  20. Value change in oil and gas production: V. Incorporation of uncertainties and determination of relative importance

    International Nuclear Information System (INIS)

    Lerche, I.; Noeth, S.

    2002-01-01

    The influence of two fundamentally different types of uncertainty on the value of oil field production are investigated here. First considered is the uncertainty caused by the fact that the expected value estimate is not one of the possible outcomes. To correctly allow for the risk attendant upon using the expected value as a measure of worth, even with statistically sharp parameters, one needs to incorporate the uncertainty of the expected value. Using a simple example we show how such incorporation allows for a clear determination of the relative risk of projects that may have the same expected value but very different risks. We also show how each project can be risked on its own using the expected value and variance. This uncertainty type is due to the possible pathways for different outcomes even when parameters categorizing the system are taken to be known. Second considered is the risk due to the fact that parameters in oil field estimates are just estimates and, as such, have their own intrinsic errors that influence the possible outcomes and make them less certain. This sort of risk depends upon the uncertainty of each parameter, and also the type of distribution the parameters are taken to be drawn from. In addition, not all uncertainties in parameters values are of equal importance in influencing an outcome probability. We show how can determine the relative importance for the parameters and so determine where to place effort to resolve the dominant contributions to risk if it is possible to do so. Considerations of whether to acquire new information, and also whether to undertake further studies under such an uncertain environment, are used as vehicles to address these concerns of risk due to uncertainty. In general, an oil field development project has to contend with all the above types of risk and uncertainty. It is therefore of importance to have quantitative measures of risk so that one can compare and contrast the various effects, and so that

  1. Selection of Suitable Endogenous Reference Genes for Relative Copy Number Detection in Sugarcane

    Directory of Open Access Journals (Sweden)

    Bantong Xue

    2014-05-01

    Full Text Available Transgene copy number has a great impact on the expression level and stability of exogenous gene in transgenic plants. Proper selection of endogenous reference genes is necessary for detection of genetic components in genetically modification (GM crops by quantitative real-time PCR (qPCR or by qualitative PCR approach, especially in sugarcane with polyploid and aneuploid genomic structure. qPCR technique has been widely accepted as an accurate, time-saving method on determination of copy numbers in transgenic plants and on detection of genetically modified plants to meet the regulatory and legislative requirement. In this study, to find a suitable endogenous reference gene and its real-time PCR assay for sugarcane (Saccharum spp. hybrids DNA content quantification, we evaluated a set of potential “single copy” genes including P4H, APRT, ENOL, CYC, TST and PRR, through qualitative PCR and absolute quantitative PCR. Based on copy number comparisons among different sugarcane genotypes, including five S. officinarum, one S. spontaneum and two S. spp. hybrids, these endogenous genes fell into three groups: ENOL-3—high copy number group, TST-1 and PRR-1—medium copy number group, P4H-1, APRT-2 and CYC-2—low copy number group. Among these tested genes, P4H, APRT and CYC were the most stable, while ENOL and TST were the least stable across different sugarcane genotypes. Therefore, three primer pairs of P4H-3, APRT-2 and CYC-2 were then selected as the suitable reference gene primer pairs for sugarcane. The test of multi-target reference genes revealed that the APRT gene was a specific amplicon, suggesting this gene is the most suitable to be used as an endogenous reference target for sugarcane DNA content quantification. These results should be helpful for establishing accurate and reliable qualitative and quantitative PCR analysis of GM sugarcane.

  2. The relative importance of seed competition, resource competition and perturbations on community structure

    Directory of Open Access Journals (Sweden)

    K. Bohn

    2011-05-01

    Full Text Available While the regional climate is the primary selection pressure for whether a plant strategy can survive, however, competitive interactions strongly affect the relative abundances of plant strategies within communities. Here, we investigate the relative importance of competition and perturbations on the development of vegetation community structure. To do so, we develop DIVE (Dynamics and Interactions of VEgetation, a simple general model that links plant strategies to their competitive dynamics, using growth and reproduction characteristics that emerge from climatic constraints. The model calculates population dynamics based on establishment, mortality, invasion and exclusion in the presence of different strengths of perturbations, seed and resource competition. The highest levels of diversity were found in simulations without competition as long as mortality is not too high. However, reasonable successional dynamics were only achieved when resource competition is considered. Under high levels of competition, intermediate levels of perturbations were required to obtain coexistence. Since succession and coexistence are observed in plant communities, we conclude that the DIVE model with competition and intermediate levels of perturbation represents an adequate way to model population dynamics. Because of the simplicity and generality of DIVE, it could be used to understand vegetation structure and functioning at the global scale and the response of vegetation to global change.

  3. Quantifying relative importance: Computing standardized effects in models with binary outcomes

    Science.gov (United States)

    Grace, James B.; Johnson, Darren; Lefcheck, Jonathan S.; Byrnes, Jarrett E.K.

    2018-01-01

    Scientists commonly ask questions about the relative importances of processes, and then turn to statistical models for answers. Standardized coefficients are typically used in such situations, with the goal being to compare effects on a common scale. Traditional approaches to obtaining standardized coefficients were developed with idealized Gaussian variables in mind. When responses are binary, complications arise that impact standardization methods. In this paper, we review, evaluate, and propose new methods for standardizing coefficients from models that contain binary outcomes. We first consider the interpretability of unstandardized coefficients and then examine two main approaches to standardization. One approach, which we refer to as the Latent-Theoretical or LT method, assumes that underlying binary observations there exists a latent, continuous propensity linearly related to the coefficients. A second approach, which we refer to as the Observed-Empirical or OE method, assumes responses are purely discrete and estimates error variance empirically via reference to a classical R2 estimator. We also evaluate the standard formula for calculating standardized coefficients based on standard deviations. Criticisms of this practice have been persistent, leading us to propose an alternative formula that is based on user-defined “relevant ranges”. Finally, we implement all of the above in an open-source package for the statistical software R.

  4. The reactor core configuration and important systems related to physics tests of Daya Bay NPP

    International Nuclear Information System (INIS)

    Tao Shaoping

    1995-06-01

    A brief introduction to reactor core configuration and important systems related to physics tests of Daya Bay NPP is given. These systems involve the reactor core system (COR), the full length rod control system (RGL), the in-core instrumentation system (RIC), the out-of-core nuclear instrumentation system (RPN), and the LOCA surveillance system (LSS), the centralized data processing system (KIT) and the test data acquisition system (KDO). In addition, that the adjustment and evaluation of boron concentration related to other systems, for example the reactor coolant system (RCP), the chemical and volume control system (RCV), the reactor boron and water makeup system (REA), the nuclear sampling system (REN) and the reactor control system (RRC), etc. is also described. Analysis of these systems helps not only to familiarize their functions and acquires a deepen understanding for the principle procedure, points for attention and technical key of the core physics tests, but also to further analyze the test results. (3 refs., 11 figs., 1 tab.)

  5. Diabetes and oral health: the importance of oral health-related behavior.

    Science.gov (United States)

    Kanjirath, Preetha P; Kim, Seung Eun; Rohr Inglehart, Marita

    2011-01-01

    The objective of this study was to explore oral health-related behavior, how patients with diabetes differ from patients not diagnosed with diabetes in their oral health and whether oral health-related behavior moderates the oral health status of patients with diabetes. Survey and chart review data were collected from 448 patients (52% male, 48% female, average age: 57 years) of which 77 were diagnosed with diabetes (17%). Patients with diabetes had a higher percentage of teeth with mobility than those not diagnosed with diabetes (14% vs. 8%, p=0.023), as well as gingival recession (16% vs. 12%, p=0.035) and more teeth with recession in the esthetic zone (1.17 vs. 0.88, p=0.046). They also had more decayed, missing and filled surfaces due to caries (101 vs. 82, pteeth due to caries (11 vs. 7, pbrushed and flossed less frequently. Patients with diabetes who did not brush regularly had poorer periodontal health (percentage of teeth with probing depth of teeth: 32% vs. 15%, p=0.033) than regularly brushing patients with diabetes. Educating patients with diabetes about the importance of good oral self care needs to become a priority for their oral health care providers.

  6. Number needed to treat and number needed to harm with paliperidone palmitate relative to long-acting haloperidol, bromperidol, and fluphenazine decanoate for treatment of patients with schizophrenia

    Directory of Open Access Journals (Sweden)

    Srihari Gopal

    2011-03-01

    Full Text Available Srihari Gopal1, Joris Berwaerts1, Isaac Nuamah1, Kasem Akhras2, Danielle Coppola1, Ella Daly1, David Hough1, Joseph Palumbo11Johnson & Johnson Pharmaceutical Research & Development, LLC, Raritan, NJ, USA; 2Johnson & Johnson Pharmaceutical Services, LLC, Raritan, NJ, USABackground: We analyzed data retrieved through a PubMed search of randomized, placebo-controlled trials of first-generation antipsychotic long-acting injectables (haloperidol decanoate, bromperidol decanoate, and fluphenazine decanoate, and a company database of paliperidone palmitate, to compare the benefit-risk ratio in patients with schizophrenia.Methods: From the eight studies that met our selection criteria, two efficacy and six safety parameters were selected for calculation of number needed to treat (NNT, number needed to harm (NNH, and the likelihood of being helped or harmed (LHH using comparisons of active drug relative to placebo. NNTs for prevention of relapse ranged from 2 to 5 for paliperidone palmitate, haloperidol decanoate, and fluphenazine decanoate, indicating a moderate to large effect size.Results: Among the selected maintenance studies, NNH varied considerably, but indicated a lower likelihood of encountering extrapyramidal side effects, such as akathisia, tremor, and tardive dyskinesia, with paliperidone palmitate versus placebo than with first-generation antipsychotic depot agents versus placebo. This was further supported by an overall higher NNH for paliperidone palmitate versus placebo with respect to anticholinergic use and Abnormal Involuntary Movement Scale positive score. LHH for preventing relapse versus use of anticholinergics was 15 for paliperidone palmitate and 3 for fluphenazine decanoate, favoring paliperidone palmitate.Conclusion: Overall, paliperidone palmitate had a similar NNT and a more favorable NNH compared with the first-generation long-acting injectables assessed.Keywords: long-acting injectables, first-generation antipsychotics

  7. The relative dietary importance of haem and non-haem iron

    International Nuclear Information System (INIS)

    Bezwoda, W.R.; Bothwell, T.H.; Charlton, R.W.; Torrance, J.D.; MacPhail, A.P.; Derman, D.P.; Mayet, F.

    1983-01-01

    A study was undertaken to find out the relative amounts of haem and non-haem iron absorbed from meals in which varying amounts of these substances were present. Four meals, each containing 6 mg of iron but with varying ratios of haem and non-haem iron, were fed to two groups of subjects, each group receiving two meals. The geometric mean percentage absorption of non-haem iron decreased from 18,0% (SD range 14,6-22,3%) to 6,4% (SD range 3,4-11,8%) as the non-haem iron content of the meal increased from 1,52 mg to 5,72 mg - there was therefore little variation in the actual amounts of non-haem iron absorbed from the different meals. In contrast, the geometric mean absorption of haem iron was approximately 20% from all four meals, although the haem iron content varied between 0,28 mg and 4,48 mg. The amount of haem iron absorbed was thus a linear function of the amount of haem iron in the meal. Two points emerged from the study. Firstly, the relative importance of haem iron in overall iron nutrition was confirmed. Secondly, the fact that the pattern of absorption in relation to dosage was so different from haem iron and non-haem iron suggested that a controlling mechanism for non-haem iron absorption may be located at the mucosal surface. This conclusion is based on the fact that haem iron, the percentage absorption of which was found to be independent of the size of the dose, is absorped into the mucosal cell when still contained within the porphyrin ring and the iron thus bypasses some controlling mechanism at the mucosal border

  8. Evaluation of Related Risk Factors in Number of Musculoskeletal Disorders Among Carpet Weavers in Iran

    Directory of Open Access Journals (Sweden)

    Nasim Karimi

    2016-12-01

    Conclusion: According to the results of this study, it can be concluded that occupational factors are associated with the number of MSDs developing among carpet weavers. Thus, using standard tools and decreasing hours of work per day can reduce frequency of MSDs among carpet weavers.

  9. On the convergence of series of reciprocal of primes related to the Fermat numbers

    Czech Academy of Sciences Publication Activity Database

    Křížek, Michal; Luca, F.; Somer, L.

    2002-01-01

    Roč. 97, č. 1 (2002), s. 95-112 ISSN 0022-314X Institutional research plan: CEZ:AV0Z1019905 Keywords : Fermat numbers%elite primes%density Subject RIV: BA - General Mathematics Impact factor: 0.365, year: 2002

  10. Factors Related to the Number of Fast Food Meals Obtained by College Meal Plan Students

    Science.gov (United States)

    Dingman, Deirdre A.; Schulz, Mark R.; Wyrick, David L.; Bibeau, Daniel L.; Gupta, Sat N.

    2014-01-01

    Objectives: This study tested whether days on campus, financial access through a meal plan, and health consciousness were associated with number of meals that college students obtained from fast food restaurants. Participants and Methods: In April 2013, all students currently enrolled in a meal plan were invited to participate in an online survey…

  11. Microarray MAPH: accurate array-based detection of relative copy number in genomic DNA

    Directory of Open Access Journals (Sweden)

    Chan Alan

    2006-06-01

    Full Text Available Abstract Background Current methods for measurement of copy number do not combine all the desirable qualities of convenience, throughput, economy, accuracy and resolution. In this study, to improve the throughput associated with Multiplex Amplifiable Probe Hybridisation (MAPH we aimed to develop a modification based on the 3-Dimensional, Flow-Through Microarray Platform from PamGene International. In this new method, electrophoretic analysis of amplified products is replaced with photometric analysis of a probed oligonucleotide array. Copy number analysis of hybridised probes is based on a dual-label approach by comparing the intensity of Cy3-labelled MAPH probes amplified from test samples co-hybridised with similarly amplified Cy5-labelled reference MAPH probes. The key feature of using a hybridisation-based end point with MAPH is that discrimination of amplified probes is based on sequence and not fragment length. Results In this study we showed that microarray MAPH measurement of PMP22 gene dosage correlates well with PMP22 gene dosage determined by capillary MAPH and that copy number was accurately reported in analyses of DNA from 38 individuals, 12 of which were known to have Charcot-Marie-Tooth disease type 1A (CMT1A. Conclusion Measurement of microarray-based endpoints for MAPH appears to be of comparable accuracy to electrophoretic methods, and holds the prospect of fully exploiting the potential multiplicity of MAPH. The technology has the potential to simplify copy number assays for genes with a large number of exons, or of expanded sets of probes from dispersed genomic locations.

  12. The relative contribution of band number to phylogenetic accuracy in AFLP data sets.

    Science.gov (United States)

    García-Pereira, M J; Caballero, A; Quesada, H

    2011-11-01

    We examined the effect of increasing the number of sampled amplified fragment length polymorphism (AFLP) bands to reconstruct an accurate and well-supported AFLP-based phylogeny. In silico AFLP was performed using simulated DNA sequences evolving along balanced and unbalanced model trees with recent, uniform and ancient radiations and average branch lengths (from the most internal node to the tip) ranging from 0.02 to 0.05 substitutions per site. Trees were estimated by minimum evolution (ME) and maximum parsimony (MP) methods from both DNA sequences and virtual AFLP fingerprints. The comparison of the true tree with the estimated AFLP trees suggests that moderate numbers of AFLP bands are necessary to recover the correct topology with high bootstrap support values (i.e. >70%). Fewer numbers of bands are necessary for shorter tree lengths and for balanced than for unbalanced tree topologies. However, branch length estimation was rather unreliable and did not improve substantially after a certain number of bands were sampled. These results hold for different levels of genome coverage and number of taxa analysed. In silico AFLP using bacterial genomic DNA sequences recovered a well-supported tree topology that mirrored an empirical phylogeny based on a set of 31 orthologous gene sequences when as few as 263 AFLP bands were scored. These results suggest that AFLPs may be an efficient alternative to traditional DNA sequencing for accurate topology reconstruction of shallow trees when not very short ancestral branches exist. © 2011 The Authors. Journal of Evolutionary Biology © 2011 European Society For Evolutionary Biology.

  13. Optimization of approximate decision rules relative to number of misclassifications: Comparison of greedy and dynamic programming approaches

    KAUST Repository

    Amin, Talha

    2013-01-01

    In the paper, we present a comparison of dynamic programming and greedy approaches for construction and optimization of approximate decision rules relative to the number of misclassifications. We use an uncertainty measure that is a difference between the number of rows in a decision table T and the number of rows with the most common decision for T. For a nonnegative real number γ, we consider γ-decision rules that localize rows in subtables of T with uncertainty at most γ. Experimental results with decision tables from the UCI Machine Learning Repository are also presented. © 2013 Springer-Verlag.

  14. Measuring perceptions related to e-cigarettes: Important principles and next steps to enhance study validity.

    Science.gov (United States)

    Gibson, Laura A; Creamer, MeLisa R; Breland, Alison B; Giachello, Aida Luz; Kaufman, Annette; Kong, Grace; Pechacek, Terry F; Pepper, Jessica K; Soule, Eric K; Halpern-Felsher, Bonnie

    2018-04-01

    Measuring perceptions associated with e-cigarette use can provide valuable information to help explain why youth and adults initiate and continue to use e-cigarettes. However, given the complexity of e-cigarette devices and their continuing evolution, measures of perceptions of this product have varied greatly. Our goal, as members of the working group on e-cigarette measurement within the Tobacco Centers of Regulatory Science (TCORS) network, is to provide guidance to researchers developing surveys concerning e-cigarette perceptions. We surveyed the 14 TCORS sites and received and reviewed 371 e-cigarette perception items from seven sites. We categorized the items based on types of perceptions asked, and identified measurement approaches that could enhance data validity and approaches that researchers may consider avoiding. The committee provides suggestions in four areas: (1) perceptions of benefits, (2) harm perceptions, (3) addiction perceptions, and (4) perceptions of social norms. Across these 4 areas, the most appropriate way to assess e-cigarette perceptions depends largely on study aims. The type and number of items used to examine e-cigarette perceptions will also vary depending on respondents' e-cigarette experience (i.e., user vs. non-user), level of experience (e.g., experimental vs. established), type of e-cigarette device (e.g., cig-a-like, mod), and age. Continuous formative work is critical to adequately capture perceptions in response to the rapidly changing e-cigarette landscape. Most important, it is imperative to consider the unique perceptual aspects of e-cigarettes, building on the conventional cigarette literature as appropriate, but not relying on existing conventional cigarette perception items without adjustment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. The relative importance of regional, local, and evolutionary factors structuring cryptobenthic coral-reef assemblages

    Science.gov (United States)

    Ahmadia, Gabby N.; Tornabene, Luke; Smith, David J.; Pezold, Frank L.

    2018-03-01

    Factors shaping coral-reef fish species assemblages can operate over a wide range of spatial scales (local versus regional) and across both proximate and evolutionary time. Niche theory and neutral theory provide frameworks for testing assumptions and generating insights about the importance of local versus regional processes. Niche theory postulates that species assemblages are an outcome of evolutionary processes at regional scales followed by local-scale interactions, whereas neutral theory presumes that species assemblages are formed by largely random processes drawing from regional species pools. Indo-Pacific cryptobenthic coral-reef fishes are highly evolved, ecologically diverse, temporally responsive, and situated on a natural longitudinal diversity gradient, making them an ideal group for testing predictions from niche and neutral theories and effects of regional and local processes on species assemblages. Using a combination of ecological metrics (fish density, diversity, assemblage composition) and evolutionary analyses (testing for phylogenetic niche conservatism), we demonstrate that the structure of cryptobenthic fish assemblages can be explained by a mixture of regional factors, such as the size of regional species pools and broad-scale barriers to gene flow/drivers of speciation, coupled with local-scale factors, such as the relative abundance of specific microhabitat types. Furthermore, species of cryptobenthic fishes have distinct microhabitat associations that drive significant differences in assemblage community structure between microhabitat types, and these distinct microhabitat associations are phylogenetically conserved over evolutionary timescales. The implied differential fitness of cryptobenthic fishes across varied microhabitats and the conserved nature of their ecology are consistent with predictions from niche theory. Neutral theory predictions may still hold true for early life-history stages, where stochastic factors may be more

  16. Relative importance and interactions of furan precursors in sterilised, vegetable-based food systems.

    Science.gov (United States)

    Palmers, Stijn; Grauwet, Tara; Buvé, Carolien; Vanratingen, Koen; Kebede, Biniam T; Goos, Peter; Hendrickx, Marc E; Van Loey, Ann

    2016-01-01

    Mitigation strategies aimed at an intervention in the reaction pathways for furan formation (e.g., by adjusting precursor concentrations) might offer an additional route for furan reduction in sterilised, vegetable-based foods, without adverse effects on other food safety or quality attributes. As a first step towards product reformulation, the aim of the present study was to determine the relative importance and interactions of possible furan precursors in these types of foods. Based on an I-optimal experimental design, potato purée (naturally low in furan precursors) was spiked with known amounts of sugars, ascorbic acid, olive oil and β-carotene, and subjected to a thermal sterilisation. Significant correlations were observed between furan concentrations after thermal treatment and starting concentrations of ascorbic acid and monosaccharides (i.e., fructose and glucose). Ascorbic acid had a clear furan-reducing effect as an antioxidant by protecting (polyunsaturated) fatty acids against oxidative degradation. Fructose and glucose were the main precursors, which can most probably be attributed to their high, but realistic, concentrations in the product. The contributions of fatty acids and β-carotene were strongly dependent on redox interactions with other food constituents. In the same potato purées, only low concentrations (0-2 ng g(-1) purée) of 2-methylfuran were detected, indicating that the direct importance of the spiked food constituents as a precursor for methylfuran formation was rather small. Based on the results of this study, reducing the amount of monosaccharides or adjusting the redox conditions of the matrix are suggested as two possible approaches for furan mitigation on the product side.

  17. Does the number of implants have any relation with peri-implant disease?

    Directory of Open Access Journals (Sweden)

    Bernardo Born PASSONI

    2014-10-01

    Full Text Available Objective: The aim of this study was to evaluate the relationship between the number of pillar implants of implant-supported fixed prostheses and the prevalence of periimplant disease. Material and Methods: Clinical and radiographic data were obtained for the evaluation. The sample consisted of 32 patients with implant-supported fixed prostheses in function for at least one year. A total of 161 implants were evaluated. Two groups were formed according to the number of implants: G1 ≤5 implants and G2 >5 implants. Data collection included modified plaque index (MPi, bleeding on probing (BOP, probing depth (PD, width of keratinized mucosa (KM and radiographic bone loss (BL. Clinical and radiographic data were grouped for each implant in order to conduct the diagnosis of mucositis or peri-implantitis. Results: Clinical parameters were compared between groups using Student’s t test for numeric variables (KM, PD and BL and Mann-Whitney test for categorical variables (MPi and BOP. KM and BL showed statistically significant differences between both groups (p<0.001. Implants from G1 – 19 (20.43% – compared with G2 – 26 (38.24% – showed statistically significant differences regarding the prevalence of peri-implantitis (p=0.0210. Conclusion: It seems that more than 5 implants in total fixed rehabilitations increase bone loss and consequently the prevalence of implants with periimplantitis. Notwithstanding, the number of implants does not have any influence on the prevalence of mucositis.

  18. Evaluation of Related Risk Factors in Number of Musculoskeletal Disorders Among Carpet Weavers in Iran.

    Science.gov (United States)

    Karimi, Nasim; Moghimbeigi, Abbas; Motamedzade, Majid; Roshanaei, Ghodratollah

    2016-12-01

    Musculoskeletal disorders (MSDs) are a common problem among carpet weavers. This study was undertaken to introduce affecting personal and occupational factors in developing the number of MSDs among carpet weavers. A cross-sectional study was performed among 862 weavers in seven towns with regard to workhouse location in urban or rural regions. Data were collected by using questionnaires that contain personal, workplace, and information tools and the modified Nordic MSDs questionnaire. Statistical analysis was performed by applying Poisson and negative binomial mixed models using a full Bayesian hierarchical approach. The deviance information criterion was used for comparison between models and model selection. The majority of weavers (72%) were female and carpet weaving was the main job of 85.2% of workers. The negative binomial mixed model with lowest deviance information criterion was selected as the best model. The criteria showed the convergence of chains. Based on 95% Bayesian credible interval, the main job and weaving type variables statistically affected the number of MSDs, but variables age, sex, weaving comb, work experience, and carpet weaving looms were not significant. According to the results of this study, it can be concluded that occupational factors are associated with the number of MSDs developing among carpet weavers. Thus, using standard tools and decreasing hours of work per day can reduce frequency of MSDs among carpet weavers.

  19. Age-related macular degeneration: the importance of family history as a risk factor.

    Science.gov (United States)

    Shahid, Humma; Khan, Jane C; Cipriani, Valentina; Sepp, Tiina; Matharu, Baljinder K; Bunce, Catey; Harding, Simon P; Clayton, David G; Moore, Anthony T; Yates, John R W

    2012-03-01

    Family history is considered a risk factor for age-related macular degeneration (AMD). With the advent of effective therapy for the disease, the importance of family history merits further investigation. This study quantifies the risk associated with family history, first, by a case-control study of reported family history and, second, by examining the siblings of AMD cases. The authors recruited cases with advanced AMD, spouses and siblings. All subjects were carefully phenotyped. Clinical findings in the siblings were compared with spouses. Information about family history was collected. The ORs for reported family history of AMD were calculated. Analyses were adjusted for age, smoking and genotype. 495 AMD cases, 259 spouses and 171 siblings were recruited. The OR for AMD was 27.8 (CI 3.8 to 203.0; p=0.001) with a reported family history of an affected parent and 12.0 (CI 3.7 to 38.6; p<0.0001) with a history of an affected sibling. ORs adjusted for age and smoking were higher. Examination of siblings confirmed their increased risk with 23% affected by AMD and an OR of 10.8 (4.5 to 25.8; p<0.0001). Adjusting for age increased the OR to 16.1 (6.2 to 41.8). The risk of AMD is greatly increased by having an affected first-degree relative. Those at risk need to be made aware of this and AMD patients should advise siblings and children to seek prompt ophthalmological advice if they develop visual symptoms of distortion or reduced vision.

  20. Baseline neurocognitive testing in sports-related concussions: the importance of a prior night's sleep.

    Science.gov (United States)

    McClure, D Jake; Zuckerman, Scott L; Kutscher, Scott J; Gregory, Andrew J; Solomon, Gary S

    2014-02-01

    The management of sports-related concussions (SRCs) utilizes serial neurocognitive assessments and self-reported symptom inventories to assess recovery and safety for return to play (RTP). Because postconcussive RTP goals include symptom resolution and a return to neurocognitive baseline levels, clinical decisions rest in part on understanding modifiers of this baseline. Several studies have reported age and sex to influence baseline neurocognitive performance, but few have assessed the potential effect of sleep. We chose to investigate the effect of reported sleep duration on baseline Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) performance and the number of patient-reported symptoms. We hypothesized that athletes receiving less sleep before baseline testing would perform worse on neurocognitive metrics and report more symptoms. Cross-sectional study; Level of evidence, 3. We retrospectively reviewed 3686 nonconcussed athletes (2371 male, 1315 female; 3305 high school, 381 college) with baseline symptom and ImPACT neurocognitive scores. Patients were stratified into 3 groups based on self-reported sleep duration the night before testing: (1) short, sleep duration on baseline ImPACT performance. A univariate ANCOVA was performed to investigate the influence of sleep on total self-reported symptoms. When controlling for age and sex as covariates, the MANCOVA revealed significant group differences on ImPACT reaction time, verbal memory, and visual memory scores but not visual-motor (processing) speed scores. An ANCOVA also revealed significant group differences in total reported symptoms. For baseline symptoms and ImPACT scores, subsequent pairwise comparisons revealed these associations to be most significant when comparing the short and intermediate sleep groups. Our results indicate that athletes sleeping fewer than 7 hours before baseline testing perform worse on 3 of 4 ImPACT scores and report more symptoms. Because SRC management and RTP

  1. Adhesive systems: important aspects related to their composition and clinical use

    Directory of Open Access Journals (Sweden)

    Mario Honorato Silva e Souza Junior

    2010-06-01

    Full Text Available This literature review article addresses the types and the main components of different etch-and-rinse and self-etch adhesive systems available in the market, and relates them to their function, possible chemical interactions and infuence of handling characteristics. Scanning electron microscopy (SEM images are presented to characterize the interface between adhesives and dentin. Adhesive systems have been recently classifed according to their adhesion approaches in etch-and-rinse, self-etch and glass ionomer. The etch-and-rinse systems require a specifc acid-etch procedure and may be performed in two or three steps. Self-etch systems employ acidic monomers that demineralize and impregnate dental substrates almost at the same time. These systems are separated in one or two steps. Some advantages and defciencies were noted for etch-and-rinse and self-etch approaches, mainly for the simplifed ones due to some chemical associations and interactions. The SEM micrographs illustrate different relationships between adhesive systems and dental structures, particularly dentin. The knowledge of composition, characteristics and mechanisms of adhesion of each adhesive system is of fundamental importance to permit the adoption of ideal bonding strategies under clinical conditions.

  2. Relative importance of social status and physiological need in determining leadership in a social forager.

    Science.gov (United States)

    Öst, Markus; Jaatinen, Kim

    2013-01-01

    Group decisions on the timing of mutually exclusive activities pose a dilemma: monopolized decision-making by a single leader compromises the optimal timing of activities by the others, while independent decision-making by all group members undermines group coherence. Theory suggests that initiation of foraging should be determined by physiological demand in social foragers, thereby resolving the dilemma of group coordination. However, empirical support is scant, perhaps because intrinsic qualities predisposing individuals to leadership (social status, experience or personality), or their interactions with satiation level, have seldom been simultaneously considered. Here, we examine which females initiated foraging in eider (Somateria mollissima) brood-rearing coalitions, characterized by female dominance hierarchies and potentially large individual differences in energy requirements due to strenuous breeding effort. Several physiological and social factors, except for female breeding experience and boldness towards predators, explained foraging initiation. Initiators spent a larger proportion of time submerged during foraging bouts, had poorer body condition and smaller structural size, but they were also aggressive and occupied central positions. Initiation probability also declined with female group size as expected given random assignment of initiators. However, the relative importance of physiological predictors of leadership propensity (active foraging time, body condition, structural size) exceeded those of social predictors (aggressiveness, spatial position) by an order of magnitude. These results confirm recent theoretical work suggesting that 'leading according to need' is an evolutionary viable strategy regardless of group heterogeneity or underlying dominance structure.

  3. Relative importance of social status and physiological need in determining leadership in a social forager.

    Directory of Open Access Journals (Sweden)

    Markus Öst

    Full Text Available Group decisions on the timing of mutually exclusive activities pose a dilemma: monopolized decision-making by a single leader compromises the optimal timing of activities by the others, while independent decision-making by all group members undermines group coherence. Theory suggests that initiation of foraging should be determined by physiological demand in social foragers, thereby resolving the dilemma of group coordination. However, empirical support is scant, perhaps because intrinsic qualities predisposing individuals to leadership (social status, experience or personality, or their interactions with satiation level, have seldom been simultaneously considered. Here, we examine which females initiated foraging in eider (Somateria mollissima brood-rearing coalitions, characterized by female dominance hierarchies and potentially large individual differences in energy requirements due to strenuous breeding effort. Several physiological and social factors, except for female breeding experience and boldness towards predators, explained foraging initiation. Initiators spent a larger proportion of time submerged during foraging bouts, had poorer body condition and smaller structural size, but they were also aggressive and occupied central positions. Initiation probability also declined with female group size as expected given random assignment of initiators. However, the relative importance of physiological predictors of leadership propensity (active foraging time, body condition, structural size exceeded those of social predictors (aggressiveness, spatial position by an order of magnitude. These results confirm recent theoretical work suggesting that 'leading according to need' is an evolutionary viable strategy regardless of group heterogeneity or underlying dominance structure.

  4. The relative importance of rapid evolution for plant-microbe interactions depends on ecological context.

    Science.gov (United States)

    Terhorst, Casey P; Lennon, Jay T; Lau, Jennifer A

    2014-06-22

    Evolution can occur on ecological time-scales, affecting community and ecosystem processes. However, the importance of evolutionary change relative to ecological processes remains largely unknown. Here, we analyse data from a long-term experiment in which we allowed plant populations to evolve for three generations in dry or wet soils and used a reciprocal transplant to compare the ecological effect of drought and the effect of plant evolutionary responses to drought on soil microbial communities and nutrient availability. Plants that evolved under drought tended to support higher bacterial and fungal richness, and increased fungal : bacterial ratios in the soil. Overall, the magnitudes of ecological and evolutionary effects on microbial communities were similar; however, the strength and direction of these effects depended on the context in which they were measured. For example, plants that evolved in dry environments increased bacterial abundance in dry contemporary environments, but decreased bacterial abundance in wet contemporary environments. Our results suggest that interactions between recent evolutionary history and ecological context affect both the direction and magnitude of plant effects on soil microbes. Consequently, an eco-evolutionary perspective is required to fully understand plant-microbe interactions.

  5. Hurwitz numbers, moduli of curves, topological recursion, Givental's theory and their relations

    NARCIS (Netherlands)

    Spitz, L.

    2014-01-01

    The study of curves is an important area of research in algebraic geometry and mathematical physics. In my thesis I study so-called moduli spaces of curves; these are spaces that parametrize all curves with some specified properties. In particular, I study maps from curves to other spaces, recursive

  6. Correlation study regarding the pelvic floor hypotonia in relation to labour, age and number of births

    Directory of Open Access Journals (Sweden)

    Doriana Ioana CIOBANU

    2017-03-01

    Full Text Available Background. During pregnancy, there is an increased pressure on pelvic floor. During labour and delivery the pelvic floor is stretched and can be damaged, leading to urine leakage, mostly during laughing, sneezing, coughing, running. This condition is called urinary incontinence. Aim. This paperwork aims to emphasize if there is a significant correlation between labor parameters, age, number of deliveries and the presence of pelvic floor hypotonia and urinary incontinence in women, after delivery. Material and method. Study was made on 24 women in the first days after delivery, ages between 21- 42 years old. 66,7% are primiparous, 33,3% are multiparous. As the assessment tools were used: stop urine test, number of perineal muscle contractions, questionnaire regarding the presence of urge urinary incontinence. Results. From the total number of subjects, 33.3% have stress incontinence and 29.2% have urge incontinence. There is a significant correlation between the presence of urinary incontinence and living environment [p = 0,014, (df. = 1], smoking [p = 0,014], the onset of labor [p = 0,014], administration of antispaspasmodic medication in labor [p = 0,010], administration of antialgic medication [p = 0,014] and the duration of delivery period [p = 0,028]. Conclusions. From the 24 subjects, 62,5% of them have urinary incontinence after labor and delivery. From these, 33.3% have stress incontinence, and 29.2% have urge incontinence. After labor and delivery more affected are fast fibers of perineal muscles, responsible withholding the urine during coughing, sneezing, lifting objects, going upstairs, as well as withholding the urine in case of overflow bladder. After labor and delivery, most women have hypotonia of perineal muscles.

  7. Assessing the relative importance of dispersal in plant communities using an ecoinformatics approach

    NARCIS (Netherlands)

    Ozinga, W.A.; Hennekens, S.M.; Schaminée, J.H.J.; Bekker, R.M.; Prinzing, A.; Bonn, S.; Poschlod, P.; Tackenberg, O.; Thompson, K.; Bakker, J.P.; Groenendael, van J.M.

    2005-01-01

    Increased insight into the factors that determine the importance of dispersal limitation on species richness and species composition is of paramount importance for conservation and restoration ecology. One way to explore the importance of dispersal limitation is to use seed-sowing experiments, but

  8. Applying citizen-science data and mark-recapture models to estimate numbers of migrant golden eagles in an important bird area in eastern North America

    Science.gov (United States)

    Dennhardt, Andrew J.; Duerr, Adam E.; Brandes, David; Katzner, Todd

    2017-01-01

    Estimates of population abundance are important to wildlife management and conservation. However, it can be difficult to characterize the numbers of broadly distributed, low-density, and elusive bird species. Although Golden Eagles (Aquila chrysaetos) are rare, difficult to detect, and broadly distributed, they are concentrated during their autumn migration at monitoring sites in eastern North America. We used hawk-count data collected by citizen scientists in a virtual mark–recapture modeling analysis to estimate the numbers of Golden Eagles that migrate in autumn along Kittatinny Ridge, an Important Bird Area in Pennsylvania, USA. In order to evaluate the sensitivity of our abundance estimates to variation in eagle capture histories, we applied candidate models to 8 different sets of capture histories, constructed with or without age-class information and using known mean flight speeds 6 1, 2, 4, or 6 SE for eagles to travel between hawk-count sites. Although some abundance estimates were produced by models that poorly fitted the data (ĉ > 3.0), 2 sets of population estimates were produced by acceptably performing models (cˆ less than or equal to 3.0). Application of these models to count data from November, 2002–2011, suggested a mean population abundance of 1,354 6 117 SE (range: 873–1,938). We found that Golden Eagles left the ridgeline at different rates and in different places along the route, and that typically ,50% of individuals were detected at the hawk-count sites. Our study demonstrates a useful technique for estimating population abundance that may be applicable to other migrant species that are repeatedly detected at multiple monitoring sites along a topographic diversion or leading line.

  9. Common pitfalls in statistical analysis: Absolute risk reduction, relative risk reduction, and number needed to treat

    Science.gov (United States)

    Ranganathan, Priya; Pramesh, C. S.; Aggarwal, Rakesh

    2016-01-01

    In the previous article in this series on common pitfalls in statistical analysis, we looked at the difference between risk and odds. Risk, which refers to the probability of occurrence of an event or outcome, can be defined in absolute or relative terms. Understanding what these measures represent is essential for the accurate interpretation of study results. PMID:26952180

  10. Home-School Relations. The Montessori Observer. Volume 30, Number 1

    Science.gov (United States)

    International Montessori Society (NJ3), 2009

    2009-01-01

    "The Montessori Observer" is mailed four times each year, in March, May, September and November, to Society members throughout the world. The purpose is to provide news and information about the Society's work in Montessori education, and to extend awareness. This issue contains a feature article, "Home-School Relations," by…

  11. Anxiety as Related to Thinking and Forgetting. What Research Says to the Teacher Series, Number 30.

    Science.gov (United States)

    Lighthall, Frederick F.

    The purpose of this pamphlet is to increase teachers' comprehension of anxiety and its relation to children's thinking and forgetting, to their problem solving ability and their sense of competence. The pamphlet describes four parts of the anxiety experience: 1) the anxiety cue, the particular thought, memory, or sensation which precipitates the…

  12. Relational Priming Based on a Multiplicative Schema for Whole Numbers and Fractions

    Science.gov (United States)

    DeWolf, Melissa; Son, Ji Y.; Bassok, Miriam; Holyoak, Keith J.

    2017-01-01

    Why might it be (at least sometimes) beneficial for adults to process fractions componentially? Recent research has shown that college-educated adults can capitalize on the bipartite structure of the fraction notation, performing more successfully with fractions than with decimals in relational tasks, notably analogical reasoning. This study…

  13. Relation between number of hemopoietic stem cells in newborn mice and their radiosensitivity

    International Nuclear Information System (INIS)

    Sutter, T.; Maes, J.; Gerber, G.B.; Leonard, A.

    1985-01-01

    Fractionation of a radiation exposure causes greater damage in newborn mice than a single application since it induces radioresistant foetal hemopoietic stem cells to differentiate prematurely to more radiosensitive adult ones. In the present investigation, it was studied whether other agents that give rise to extensive stem cell destruction also lead to such a change in radiosensitivity. Indeed, treatment with cytostatic drugs which reduces the number of spleen colony forming units (CFU-s) and total cells also diminished the D 0 value of the surviving cells 3 days later. Adriamycin was most effective in causing damage to hemopoietic stem cells and in inducing micronuclei in bone marrow; it also had the most marked action on the D 0 of the surviving stem cells. (orig.)

  14. The relative importance of different types of rewards for employee motivation and commitment in South Africa

    Directory of Open Access Journals (Sweden)

    Aleeshah Nujjoo

    2012-02-01

    Full Text Available Orientation: Employees’ perceptions of rewards are related to their affective commitment and intrinsic motivation, which have been associated with staff turnover.Research purpose: The study sought to establish the relationship between intrinsic and different extrinsic rewards with intrinsic motivation and affective commitment.Motivation for the study: South African organisations are grappling with employee retention. Literature shows that employees who are more motivated and committed to their organisation are less likely to quit. Rewards management strategies serve to create a motivated and committed workforce. Using the correct types of rewards can thus provide a competitive advantage.Research design, approach and method: A cross-sectional, correlational study was conducted. Questionnaire data of 399 South African employees were analysed using bivariate correlations and multiple regression.Main findings: Three main findings emerged. Firstly, there is a relationship between all types of rewards investigated and the two outcome variables. Secondly, this relationship is stronger for intrinsic than for extrinsic rewards and thirdly, monetary rewards do not account for the variance in intrinsic motivation above that of non-monetary rewards.Practical/managerial implications: Rewards management strategies should focus on job characteristics and designs to increase staff intrinsic rewards and include non-monetary rewards, such as supportive leadership, to encourage employees’ intrinsic motivation and affective commitment.Contribution/value-add: This research demonstrated the important role different rewards, particularly intrinsic non-monetary rewards, play in creating a committed and motivated workforce. The insights gained from this study can promote organisational effectiveness. Suggestions of how to expand on and refine the current study are addressed.

  15. The relative importance of the adsorption and partitioning mechanisms in hydrophilic interaction liquid chromatography.

    Science.gov (United States)

    Gritti, Fabrice; Höltzel, Alexandra; Tallarek, Ulrich; Guiochon, Georges

    2015-01-09

    We propose an original model of effective diffusion along packed beds of mesoporous particles for HILIC developed by combining Torquatos model for heterogeneous beds (external eluent+particles), Landauers model for porous particles (solid skeleton+internal eluent), and the time-averaged model for the internal eluent (bulk phase+diffuse water (W) layer+rigid W layer). The new model allows to determine the analyte concentration in rigid and diffuse W layer from the experimentally determined retention factor and intra-particle diffusivity and thus to distinguish the retentive contributions from adsorption and partitioning. We apply the model to investigate the separation of toluene (TO, as a non-retained compound), nortriptyline (NT), cytosine (CYT), and niacin (NA) on an organic ethyl/inorganic silica hybrid adsorbent. Elution conditions are varied through the choice of a third solvent (W, ethanol, tetrahydrofuran (THF), acetonitrile (ACN), or n-hexane) in a mobile phase (MP) of ACN/aqueous acetate buffer (pH 5)/third solvent (90/5/5, v/v/v). Whereas NA and CYT retention factors increase monotonously from W to n-hexane as third solvent, NT retention reaches its maximum with polar aprotic third solvents. The involved equilibrium constants for adsorption and partitioning, however, do not follow the same trends as the overall retention factors. NT retention is dominated by partitioning and NA retention by adsorption, while CYT retention is controlled by adsorption rather than partitioning. Our results reveal that the relative importance of adsorption and partitioning mechanisms depends in a complex way from analyte properties and experimental parameters and cannot be predicted generally. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Estimating regional methane surface fluxes: the relative importance of surface and GOSAT mole fraction measurements

    Directory of Open Access Journals (Sweden)

    A. Fraser

    2013-06-01

    Full Text Available We use an ensemble Kalman filter (EnKF, together with the GEOS-Chem chemistry transport model, to estimate regional monthly methane (CH4 fluxes for the period June 2009–December 2010 using proxy dry-air column-averaged mole fractions of methane (XCH4 from GOSAT (Greenhouse gases Observing SATellite and/or NOAA ESRL (Earth System Research Laboratory and CSIRO GASLAB (Global Atmospheric Sampling Laboratory CH4 surface mole fraction measurements. Global posterior estimates using GOSAT and/or surface measurements are between 510–516 Tg yr−1, which is less than, though within the uncertainty of, the prior global flux of 529 ± 25 Tg yr−1. We find larger differences between regional prior and posterior fluxes, with the largest changes in monthly emissions (75 Tg yr−1 occurring in Temperate Eurasia. In non-boreal regions the error reductions for inversions using the GOSAT data are at least three times larger (up to 45% than if only surface data are assimilated, a reflection of the greater spatial coverage of GOSAT, with the two exceptions of latitudes >60° associated with a data filter and over Europe where the surface network adequately describes fluxes on our model spatial and temporal grid. We use CarbonTracker and GEOS-Chem XCO2 model output to investigate model error on quantifying proxy GOSAT XCH4 (involving model XCO2 and inferring methane flux estimates from surface mole fraction data and show similar resulting fluxes, with differences reflecting initial differences in the proxy value. Using a series of observing system simulation experiments (OSSEs we characterize the posterior flux error introduced by non-uniform atmospheric sampling by GOSAT. We show that clear-sky measurements can theoretically reproduce fluxes within 10% of true values, with the exception of tropical regions where, due to a large seasonal cycle in the number of measurements because of clouds and aerosols, fluxes are within 15% of true fluxes. We evaluate our

  17. Restoring lepidopteran diversity in a tropical dry forest: relative importance of restoration treatment, tree identity and predator pressure

    Directory of Open Access Journals (Sweden)

    Lizet Solis-Gabriel

    2017-05-01

    Full Text Available Tropical dry forests (TDFs have been widely transformed by human activities worldwide and the ecosystem services they provide are diminishing. There has been an urgent call for conservation and restoration of the degraded lands previously occupied by TDFs. Restoration experiences aim to recover species diversity and ecological functions. Different restoration strategies have been used to maximize plant performance including weeding, planting or using artificial mulching. In this investigation, we evaluated whether different restoration practices influence animal arrival and the reestablishment of biotic interactions. We particularly evaluated lepidopteran larvae diversity and caterpillar predation on plants established under different restoration treatments (mulching, weeding and control in the Pacific West Coast of México. This study corroborated the importance of plant host identity for lepidopteran presence in a particular area. Lepidopteran diversity and herbivory rates were not affected by the restoration treatment but they were related to tree species. In contrast, caterpillar predation marks were affected by restoration treatment, with a greater number of predation marks in control plots, while caterpillar predation marks among plant species were not significantly different. This study highlights the importance of considering the introduction of high plant species diversity when planning TDF restoration to maximize lepidopteran diversity and ecosystem functioning.

  18. Restoring lepidopteran diversity in a tropical dry forest: relative importance of restoration treatment, tree identity and predator pressure.

    Science.gov (United States)

    Solis-Gabriel, Lizet; Mendoza-Arroyo, Wendy; Boege, Karina; Del-Val, Ek

    2017-01-01

    Tropical dry forests (TDFs) have been widely transformed by human activities worldwide and the ecosystem services they provide are diminishing. There has been an urgent call for conservation and restoration of the degraded lands previously occupied by TDFs. Restoration experiences aim to recover species diversity and ecological functions. Different restoration strategies have been used to maximize plant performance including weeding, planting or using artificial mulching. In this investigation, we evaluated whether different restoration practices influence animal arrival and the reestablishment of biotic interactions. We particularly evaluated lepidopteran larvae diversity and caterpillar predation on plants established under different restoration treatments (mulching, weeding and control) in the Pacific West Coast of México. This study corroborated the importance of plant host identity for lepidopteran presence in a particular area. Lepidopteran diversity and herbivory rates were not affected by the restoration treatment but they were related to tree species. In contrast, caterpillar predation marks were affected by restoration treatment, with a greater number of predation marks in control plots, while caterpillar predation marks among plant species were not significantly different. This study highlights the importance of considering the introduction of high plant species diversity when planning TDF restoration to maximize lepidopteran diversity and ecosystem functioning.

  19. Relative Copy Number Variations of CYP2C19 in South Indian Population

    OpenAIRE

    Devendran, Anichavezhi; Uppugunduri, Chakradhara Rao Satyanarayana; Sundaram, Rajan; Shewade, Deepak Gopal; Rajagopal, Krishnamoorthy; Chandrasekaran, Adithan

    2012-01-01

    CYP2C19 is a polymorphic enzyme involved in the metabolism of clinically important drugs. Genotype-phenotype association studies of CYP2C19 have reported wide ranges in the metabolic ratios of its substrates. These discrepancies could be attributed to the variations in the promoter region and this aspect has been reported recently. The observations in the recent reports on the influence of promoter region variants on the metabolism of CYP2C19 substrates might also have been influenced by the ...

  20. Implementation Of Law Number 11 Of 2012 Concerning Child Related Criminal Justice System Concept Restorative Justice

    Directory of Open Access Journals (Sweden)

    Intan Karangan

    2016-09-01

    Full Text Available This study aims to determine how the application of the concept of restorative justice in accordance with Law No. 11 of 2012 on Child Criminal Justice system. This study uses normative namely a study that discusses the problem based on the literature and legislation relating to the matter to be investigated. Law No. 11 of 2012 on the Criminal Justice System Child has provided a new concept in the criminal justice system, especially those in the juvenile justice system. Related to the concept of Restorative Justice or restorative justice is a resolution processes involving perpetrators, victims, families, and other relevant parties in a criminal act, jointly seek solutions to the offense and its implications by emphasizing restoration and not retribution

  1. Multiple system responses program: Identification of concerns related to a number of specific regulatory issues

    International Nuclear Information System (INIS)

    Murphy, G.A.; Casada, M.L.; Palko, L.E.; Roberts, M.W.

    1989-10-01

    This document describes the activities and results of the Multiple System Responses (MSR) program conducted by the Nuclear Operations Analysis Center (NOAC) at Oak Ridge National Laboratory (ORNL). The objective of the MSR program was to gather and review documentation for several unresolved safety issues and related programs of interest, and from that documentation, describe any additional potential safety concerns. The MSR program provides information that will aid the NRC staff in making an assessment of the relative safety significance of the concerns through the established prioritization process. Judgments were not made regarding the validity of the concerns expressed by others. Rather, the concerns were documented and potential safety issues were developed and defined as specifically as possible. Twenty-one potential safety issues were developed from the documented concerns. Additional information was gathered to support the NRC efforts in reviewing these issues for prioritization. 73 refs., 2 tabs

  2. Interaction of cationic porphyrins with DNA: Importance of the number and position of the charges and minimum structural requirements for intercalation

    International Nuclear Information System (INIS)

    Sari, M.A.; Battioni, J.P.; Dupre, D.; Mansuy, D.; Le Pecq, J.B.

    1990-01-01

    Thirty-three porphyrins or metalloporphyrins corresponding to the general formula [meso-[N-methyl-4(or 3 or 2)-pyridiniumyl] n (aryl) 4-n porphyrin]M (M = H 2 , Cu II , or ClFe III ), with n = 2-4, have been synthesized and characterized by UV-visible and 1 H NMR spectroscopy and mass spectrometry. These porphyrins differ not only in the number (2-4) and position of their cationic charges but also in the steric requirements to reach even temporarily a completely planar geometry. Interaction of these porphyrins or metalloporphyrins with calf thymus DNA has been studied and their apparent affinity binding constants have been determined by use of a competition method with ethidium bromide which was applicable not only for all the free base porphyrins but also for their copper (II) or iron (III) complexes. Whatever their mode of binding may be, their apparent affinity binding constants were relatively high and a linear decrease of log K app with the number of porphyrin charges was observed. Studies of porphyrin-DNA interactions by UV and fluorescence spectroscopy, viscosimetry, and fluorescence energy transfer experiments showed that not only the tetracationic meso-tetrakis[N-methyl-4(or 3)-pyridiniumyl]porphyrins, which both involved four freely rotating meso-aryl groups, but also the corresponding tri- and dicationic porphyrins were able to intercalate into calf thymus DNA. These results show that only half of the porphyrin ring is necessary for intercalation to occur

  3. The Relative Importance of Specific Self-Efficacy Sources in Pretraining Self-Efficacy Beliefs

    Science.gov (United States)

    Howardson, Garett N.; Behrend, Tara S.

    2015-01-01

    Self-efficacy is clearly important for learning. Research identifying the most important sources of self-efficacy beliefs, however, has been somewhat limited to date in that different disciplines focus largely on different sources of self-efficacy. Whereas education researchers focus on Bandura's original sources of "enactive mastery,"…

  4. Relative importance of dissolved and food pathways for lead contamination in shrimp

    International Nuclear Information System (INIS)

    Boisson, F.; Cotret, O.; Teyssie, J.-L.; El-Baradeie, M.; Fowler, S.W.

    2003-01-01

    The relative importance of dissolved and food pathways and the influence of food type in the bioaccumulation and retention of lead in the shrimp Palaemonetes varians were examined using a radiotracer method. Shrimp were exposed to 210 Pb-labelled seawater or fed two types of 210 Pb-labelled food, viz. mussels or worms. The amount of radiotracer accumulated by shrimp was examined over a 7-day period, followed by a 1-month and a 7-day depuration period for the dissolved and food source, respectively. Steady state in the uptake was reached after 2 days exposure to dissolved lead, with a resultant estimated concentration factor of 98 ± 3. Transfer factors following ingestion of contaminated mussels and worms were lower than unity for both food types, with lead transfer from worms being significantly higher than that from mussels. Accumulation of dissolved Pb by shrimp was found to occur mainly through adsorption on the exoskeleton with a minor accumulation in the internal tissues probably resulting from the intake of seawater for osmoregulation. In contrast, lead taken up from contaminated food was readily absorbed and bound in the internal tissues of P. varians. Although the transfer of lead to P. varians through the ingestion of contaminated food was low (TF < 1%), it still represented 4 to 8% of the lead content in the prey which is a significant additional contribution of lead to the shrimp body burden. Independent of food type, following ingestion of contaminated food, approximately 23-27% of total lead accumulated in shrimp was located in the edible parts (e.g. muscle). Therefore, the food pathway is suggested to be a significant contributor to the lead transfer to humans through ingestion of contaminated shrimp. After exposure to contaminated food, lead loss kinetics were described by a two-component model, whereas Pb loss following direct uptake from seawater was best described by a three-component model. The additional compartment representing 64% of total Pb

  5. Relative importance of dissolved and food pathways for lead contamination in shrimp

    Energy Technology Data Exchange (ETDEWEB)

    Boisson, F.; Cotret, O.; Teyssie, J.-L.; El-Baradeie, M.; Fowler, S.W

    2003-12-01

    The relative importance of dissolved and food pathways and the influence of food type in the bioaccumulation and retention of lead in the shrimp Palaemonetes varians were examined using a radiotracer method. Shrimp were exposed to {sup 210}Pb-labelled seawater or fed two types of {sup 210}Pb-labelled food, viz. mussels or worms. The amount of radiotracer accumulated by shrimp was examined over a 7-day period, followed by a 1-month and a 7-day depuration period for the dissolved and food source, respectively. Steady state in the uptake was reached after 2 days exposure to dissolved lead, with a resultant estimated concentration factor of 98 {+-} 3. Transfer factors following ingestion of contaminated mussels and worms were lower than unity for both food types, with lead transfer from worms being significantly higher than that from mussels. Accumulation of dissolved Pb by shrimp was found to occur mainly through adsorption on the exoskeleton with a minor accumulation in the internal tissues probably resulting from the intake of seawater for osmoregulation. In contrast, lead taken up from contaminated food was readily absorbed and bound in the internal tissues of P. varians. Although the transfer of lead to P. varians through the ingestion of contaminated food was low (TF < 1%), it still represented 4 to 8% of the lead content in the prey which is a significant additional contribution of lead to the shrimp body burden. Independent of food type, following ingestion of contaminated food, approximately 23-27% of total lead accumulated in shrimp was located in the edible parts (e.g. muscle). Therefore, the food pathway is suggested to be a significant contributor to the lead transfer to humans through ingestion of contaminated shrimp. After exposure to contaminated food, lead loss kinetics were described by a two-component model, whereas Pb loss following direct uptake from seawater was best described by a three-component model. The additional compartment representing 64

  6. Epigenetics of autism-related impairment: copy number variation and maternal infection.

    Science.gov (United States)

    Mazina, Varvara; Gerdts, Jennifer; Trinh, Sandy; Ankenman, Katy; Ward, Tracey; Dennis, Megan Y; Girirajan, Santhosh; Eichler, Evan E; Bernier, Raphael

    2015-01-01

    Epidemiological data have suggested maternal infection and fever to be associated with increased risk of autism spectrum disorder (ASD). Animal studies show that gestational infections perturb fetal brain development and result in offspring with the core features of autism and have demonstrated that behavioral effects of maternal immune activation are dependent on genetic susceptibility. The goal of this study was to explore the impact of ASD-associated copy number variants (CNVs) and prenatal maternal infection on clinical severity of ASD within a dataset of prenatal history and complete genetic and phenotypic findings. We analyzed data from the Simons Simplex Collection sample including 1971 children with a diagnosis of ASD aged 4 to 18 years who underwent array comparative genomic hybridization screening. Information on infection and febrile episodes during pregnancy was collected through parent interview. ASD severity was clinically measured through parent-reported interview and questionnaires. We found significant interactive effects between the presence of CNVs and maternal infection during pregnancy on autistic symptomatology, such that individuals with CNVs and history of maternal infection demonstrated increased rates of social communicative impairments and repetitive/restricted behaviors. In contrast, no significant interactions were found between presence of CNVs and prenatal infections on cognitive and adaptive functioning of individuals with ASD. Our findings support a gene-environment interaction model of autism impairment, in that individuals with ASD-associated CNVs are more susceptible to the effects of maternal infection and febrile episodes in pregnancy on behavioral outcomes and suggest that these effects are specific to ASD rather than to global neurodevelopment.

  7. Research on the Impacts of Expensive Food and Luxury Goods Import Tariff Adjustment on Chinese Economy and Related Measures

    OpenAIRE

    Qishen Zhou; Mingxing Yang

    2013-01-01

    This study aims to investigate the impacts of expensive food and luxury goods import tariff adjustment on Chinese economy and related measures. Nowadays, Asia especially China has been the world’s biggest expensive food and luxury goods market. However, due to relatively higher luxury import tariff in China, most consumers have chosen to purchase expensive food and luxury goods abroad which leads to a large of domestic consumption cash outflow. Therefore, whether to cut the luxury import tari...

  8. The importance of being "me": The relation between authentic identity expression and transgender employees' work-related attitudes and experiences.

    Science.gov (United States)

    Martinez, Larry R; Sawyer, Katina B; Thoroughgood, Christian N; Ruggs, Enrica N; Smith, Nicholas A

    2017-02-01

    The present research examined the relation between authentic identity expression and transgender employees' work-related attitudes and experiences. Drawing on Kernis' (2003) theoretical conceptualization of authenticity and expanding on current workplace identity management research, we predicted that employees who had taken steps to reduce the discrepancy between their inner gender identities and their outward manifestations of gender would report more positive job attitudes and workplace experiences, in part because the reduction of this discrepancy is related to greater feelings of authenticity. In Study 1, we found that the extent to which one has transitioned was related to higher job satisfaction and perceived person-organization (P-O) fit and lower perceived discrimination. In Study 2, we replicate and extend these results by showing that the extent to which employees felt that others at work perceived them in a manner consistent with how they perceived themselves (relational authenticity) mediated the relations between extent of transition and all 3 of these outcomes. However, perceptions of alignment between one's felt and expressed identity (action authenticity) only mediated this link for job satisfaction. We discuss the theoretical and practical implications of our results, as well as avenues for future research on authenticity in the workplace. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. How "fun/importance" fit affects performance: relating implicit theories to instructions.

    Science.gov (United States)

    Bianco, Amy T; Higgins, E Tory; Klem, Adena

    2003-09-01

    People experience a regulatory fit when they employ means of goal pursuit that fit their regulatory orientation, and this fit increases motivation that can enhance performance. The present studies extend previous research on regulatory fit to the classic motivational variables of fun and importance. They also examine for the first time the effect on performance of the fit between individuals' implicit theories about a task's fun or importance and their strategic engagement of the task as fun or important as induced by task instructions. In all three studies, task performance was better when the external task instructions "fit" rather than did not fit participants' implicit theory for the task. The implications of these findings for understanding the motivational effects of fun and importance are discussed.

  10. THE ROLE AND IMPORTANCE OF “PUBLIC INFORMATION” IN POLITICAL PUBLIC RELATIONS

    OpenAIRE

    Kazım Özkan ERTÜRK

    2015-01-01

    Public relations is the practice of managing a communication process that aims to build mutual goodwill and trust between organizations and their publics with the help of publicity, information and positive image building efforts. Public information is the public relations approach which aims for providing mutual goodwill and trust by sharing the organization-related information with target audience in complete openness and honesty. Public Information, firstly introduced by Ivy Ledbette...

  11. Relative Importance of Perceived Value, Satisfaction and Perceived Risk on Willingness to Pay More

    OpenAIRE

    Demirgüneş, Banu Külter

    2015-01-01

    The consumer perceived value construct is a very important component in the consumer value literature and it has been identified as one of the most important measures for gaining a competitive advantage. All its consequences can be combined in a construct, defined as consumer behavior. The present article sustains the idea that consumer’s perceived value can been associated with satisfaction, which leads a behavioral intention such as willingness to pay a higher price. In the case of potentia...

  12. Influence of patient related factors on number of mesenchymal stromal cells reached after in vitro culture expansion for clinical treatment

    DEFF Research Database (Denmark)

    Qayyum, Abbas Ali; Kaur, Kamal Preet; Mathiasen, Anders Bruun

    2017-01-01

    of autologous stromal cells reached after in vitro culture expansion for clinical therapy. METHODS: Culture expansion data from 111 patients with IHD treated with autologous stromal cells in three clinical trials were used. We correlated the final cell count after two passages of cultivation with different...... correlation between left ventricular ejection fraction and number of MSCs was found (r = -0.287, p = .017). CONCLUSIONS: Patient related factors such as BMI, hypertension and gender may influence the number of MSCs reached after in vitro culture expansion....... patient factors. RESULTS: There was a significant relation between body mass index (BMI) and the number of adipose derived stromal cells (ASCs) reached after culture expansion and for all patients included into the three studies (r = 0.375, p = .019 and r = 0.200, p = .036, respectively). Moreover...

  13. The Marginal Distributions of a Crossing Time and Renewal Numbers Related with Two Poisson Processes are as Ph-Distributions

    Directory of Open Access Journals (Sweden)

    Mir G. H. Talpur

    2006-01-01

    Full Text Available In this paper we consider, how to find the marginal distributions of crossing time and renewal numbers related with two poisson processes by using probability arguments. The obtained results show that the one-dimension marginal distributions are N+1 order PH-distributions.

  14. White matter alterations in cocaine users are negatively related to the number of additionally (ab)used substances

    NARCIS (Netherlands)

    Kaag, A.M.; van Wingen, G.A.; Caan, M.W.A.; Homberg, J.R.; van den Brink, W.; Reneman, L.

    Diffusion tensor imaging studies have provided evidence for white matter (WM) alterations in cocaine users. While polysubstance use is a widespread phenomenon among cocaine users, its role in WM alterations in cocaine users is currently unknown. This study examined the relation between the number of

  15. [Analysis of factors related to the number of mesenchymal stem cells derived from synovial fluid of the temporomandibular joint].

    Science.gov (United States)

    Sun, Y P; Zheng, Y H; Zhang, Z G

    2017-06-09

    Objective: To analyze related factors on the number of mesenchymal stem cells in the synovial fluid of the temporomandibular joint (TMJ) and provide an research basis for understanding of the source and biological role of mesenchymal stem cells derived from synovial fluid in TMJ. Methods: One hundred and twenty-two synovial fluid samples from 91 temporomandibular disorders (TMD) patients who visited in Department of TMJ Center, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University from March 2013 to December 2013 were collected in this study, and 6 TMJ synovial fluid samples from 6 normal volunteers who were studying in the North Campus of Sun Yat-sen University were also collected, so did their clinical information. Then the relation between the number of mesenchymal stem cells derived from synovial fluid and the health status of the joints, age of donor, disc perforation, condylar bony destruction, blood containing and visual analogue scale score of pain were investigated using Mann-Whitney U test and Spearman rank correlation test. Results: The number of mesenchymal stem cells derived from synovial fluid had no significant relation with visual analogue scale score of pain ( r= 0.041, P= 0.672), blood containing ( P= 0.063), condylar bony destruction ( P= 0.371). Linear correlation between the number of mesenchymal stem cells derived from synovial fluid and age of donor was very week ( r= 0.186, P= 0.043). The number of mesenchymal stem cells up-regulated when the joint was in a disease state ( P= 0.001). The disc perforation group had more mesenchymal stem cells in synovial fluid than without disc perforation group ( P= 0.042). Conclusions: The number of mesenchymal stem cells derived from synovial fluid in TMJ has no correlation with peripheral blood circulation and condylar bony destruction, while has close relation with soft tissue structure damage of the joint.

  16. The Importance of Self-Beliefs on Relational Aggression of College Students

    Science.gov (United States)

    Weber, Dana; Kurpius, Sharon Robinson

    2011-01-01

    This study examined the interrelationships among mattering to friends, self-esteem, spirituality, and perpetration of relational aggression in friendships among 457 college students. While the three self-belief variables were positively related to each other, only spirituality and mattering to friends discriminated between men and women. Women…

  17. Challenging Assumptions of International Public Relations: When Government Is the Most Important Public.

    Science.gov (United States)

    Taylor, Maureen; Kent, Michael L.

    1999-01-01

    Explores assumptions underlying Malaysia's and the United States' public-relations practice. Finds many assumptions guiding Western theories and practices are not applicable to other countries. Examines the assumption that the practice of public relations targets a variety of key organizational publics. Advances international public-relations…

  18. The relative importance of the brand of music festivals: a customer equity perspective

    NARCIS (Netherlands)

    Leenders, M.A.A.M.

    2010-01-01

    The aim of the paper is to examine the relative impact of tangible and intangible factors on the success of music festivals. The paper draws on literature relating to hedonic consumption, customer equity, loyalty, and the success of music festivals. Data are collected among music festival goers by

  19. The importance of Justinian's codification work in the field of marital relations

    Directory of Open Access Journals (Sweden)

    Deretić Nataša

    2011-01-01

    Full Text Available This paper tries to describe theoretically some of the numerous questions regarding the marriage in Justinian's time (525-565. By finishing the work of his predecessors (Gregorian, Hermogenian, Theodosius, Justinian codified the whole of Roman law. Of course, when we speak about Justinian, we also have in mind Tribonian and other members of his team. He introduced many innovations in family, i.e. marital relations: cognate kinship (blood kinship replaced agnate kinship; the head of a family had no more 'right of life or death' (ius vitae ac necis over the family members; marriage was reformed and a lot of restrictions were abolished as well as many pagan rituals involved in the act of getting married, and the divorce was no more 'duty but right'. Under the influence of Christianity that was spread in the first century among slaves and the poor and the moral purity that had been preached by Christianity - Justinian continued the policy of his predecessors (August, Constantine, Theodosius towards strengthening marriage and family. Even in the period of spreading Christianity across the Roman Empire, ancient Roman religious rituals were becoming less common due to decreased importance of religion and ethics. Roman legislation in that period did not insist on formalities in the process of getting married; it insisted on a mutual agreement of a bride and bridegroom and after that the marriage was contracted as a 'legal union' - consensus facit nuptias - as the Romans said. In the Justinian time, although the marriage was under a great influence of Christianity, it required no church blessing for a contracted marriage. That condition will be introduced by Leo the Wise in the 9th century for the Eastern Roman Empire. According to Justinian, a marriage is 'the relationship of a husband and wife that contains permanent life community'. The procedure and the attached activities that accompany the act of getting married (engagement, dowry, premarital gift

  20. The Relative Importance of Spatial Versus Temporal Structure in the Perception of Biological Motion: An Event-Related Potential Study

    Science.gov (United States)

    Hirai, Masahiro; Hiraki, Kazuo

    2006-01-01

    We investigated how the spatiotemporal structure of animations of biological motion (BM) affects brain activity. We measured event-related potentials (ERPs) during the perception of BM under four conditions: normal spatial and temporal structure; scrambled spatial and normal temporal structure; normal spatial and scrambled temporal structure; and…

  1. The meaning and importance of vigilant attendance for the relatives of intensive care unit patients.

    Science.gov (United States)

    Plakas, Sotirios; Taket, Ann; Cant, Bob; Fouka, Georgia; Vardaki, Zambia

    2014-09-01

    To explore the meaning of vigilant attendance for relatives of critically ill patients in Greece. A plethora of international research has identified proximity to the patient to be a major concern for relatives of critically ill patients. Greece however follows a strict visiting policy in intensive care units (ICUs) so Greek relatives spend great amounts of time just outside the ICUs. This qualitative study adopted the social constructionist version of grounded theory. Data were collected from three ICUs in Athens through in depth interviews with 25 informants and approximately 10 h of observations outside the ICUs on 159 relatives. Vigilant attendance was one of the main coping mechanisms identified for relatives. Four subcategories were found to comprise vigilant attendance: (1) being as close as possible to feel relief, (2) being there to find out what is going on, (3) monitoring changes in the loved one and making own diagnosis and (4) interacting with the ICU professionals. Vigilant attendance describes the way in which relatives in Greece stayed outside the ICUs. Relatives felt satisfaction from being close as the best alternative for not actually being inside the ICU and they tried to learn what was going on by alternative methods. By seeing the patients, relatives were also able to make their own diagnoses and could therefore avoid relying solely on information given to them. However, a prerequisite for successful vigilant attendance was to get on well with doctors and nurses. Changes in visiting policies in Greece are needed to meet the needs of relatives adequately. Recommendations for changes with minimal investment of time and funding are made. © 2013 British Association of Critical Care Nurses.

  2. Which features are important for effectiveness of sport- and health-related apps?

    NARCIS (Netherlands)

    Joan Dallinga; Marije Baart de la Faille-Deutekom; Mark Janssen; Steven Vos

    2017-01-01

    In this presentation we presented the results of expert meetings. The aim was to identify which features in sport- and health-related apps contribute to effectiveness of apps. A nominal group technique was used.

  3. Importance of public relations in recycling strategies: principles and case studies.

    Science.gov (United States)

    Salhofer, Stefan; Isaac, Nicole A

    2002-07-01

    The separate collection of waste, and especially of recyclables with specific collection systems, would not be possible without the involvement of the users. Apart from the physical installations such as collection containers, collection points, etc., the motivation of the users is an essential component. Motivation can be reinforced through public relations work. In addition to the underlying technical considerations, this paper describes the difference between communication in general and public relations and specifically examines public involvement in recycling. Through the use of examples, we look at the targeted users and typical media employed. Furthermore, we analyzes the development of public involvement. The examples show that public relations for recycling strategies relies to a great extent on attitudes, habits, and access to the target group. Thus, standardized procedures cannot be developed. For these reasons, public relation activities must be planned carefully and professionally and include an analysis of the target group, choice of media, and verification of success.

  4. Fear of Falling in Women with Fibromyalgia and Its Relation with Number of Falls and Balance Performance.

    Science.gov (United States)

    Collado-Mateo, D; Gallego-Diaz, J M; Adsuar, J C; Domínguez-Muñoz, F J; Olivares, P R; Gusi, N

    2015-01-01

    To evaluate fear of falling, number of falls, and balance performance in women with FM and to examine the relationship between these variables and others, such as balance performance, quality of life, age, pain, and impact of fibromyalgia. A total of 240 women participated in this cross-sectional study. Of these, 125 had fibromyalgia. Several variables were assessed: age, fear of falling from 0 to 100, number of falls, body composition, balance performance, lower limb strength, health-related quality of life, and impact of fibromyalgia. Women with fibromyalgia reported more falls and more fear of falling. Fear of falling was associated with number of falls in the last year, stiffness, perceived balance problems, impact of FM, and HRQoL whereas the number of falls was related to fear of falling, balance performance with eyes closed, pain, tenderness to touch level, anxiety, self-reported balance problems, impact of FM, and HRQoL. FM has an impact on fear of falling, balance performance, and number of falls. Perceived balance problems seem to be more closely associated with fear of falling than objective balance performance.

  5. Fear of Falling in Women with Fibromyalgia and Its Relation with Number of Falls and Balance Performance

    Directory of Open Access Journals (Sweden)

    D. Collado-Mateo

    2015-01-01

    Full Text Available Objective. To evaluate fear of falling, number of falls, and balance performance in women with FM and to examine the relationship between these variables and others, such as balance performance, quality of life, age, pain, and impact of fibromyalgia. Methods. A total of 240 women participated in this cross-sectional study. Of these, 125 had fibromyalgia. Several variables were assessed: age, fear of falling from 0 to 100, number of falls, body composition, balance performance, lower limb strength, health-related quality of life, and impact of fibromyalgia. Results. Women with fibromyalgia reported more falls and more fear of falling. Fear of falling was associated with number of falls in the last year, stiffness, perceived balance problems, impact of FM, and HRQoL whereas the number of falls was related to fear of falling, balance performance with eyes closed, pain, tenderness to touch level, anxiety, self-reported balance problems, impact of FM, and HRQoL. Conclusion. FM has an impact on fear of falling, balance performance, and number of falls. Perceived balance problems seem to be more closely associated with fear of falling than objective balance performance.

  6. The relative importance of factors that determine log-hauling costs

    Science.gov (United States)

    A. Jeff Martin; A. Jeff Martin

    1971-01-01

    Hauling costs are a major expense to lumbermen, but little is known about which factors affect hauling costs the most. A recent Forest Service study of hauling costs on 34 logging operations sheds light on whmich factors of cost are important and which might require less attention. These results should help lumbermen adopt a cost accounting procedure and help them with...

  7. Religious and spiritual importance moderate relation between default mode network connectivity and familial risk for depression.

    Science.gov (United States)

    Svob, Connie; Wang, Zhishun; Weissman, Myrna M; Wickramaratne, Priya; Posner, Jonathan

    2016-11-10

    Individuals at high risk for depression have increased default mode network (DMN) connectivity, as well as reduced inverse connectivity between the DMN and the central executive network (CEN) [8]. Other studies have indicated that the belief in the importance of religion/spirituality (R/S) is protective against depression in high risk individuals [5]. Given these findings, we hypothesized that R/S importance would moderate DMN connectivity, potentially reducing DMN connectivity or increasing DMN-CEN inverse connectivity in individuals at high risk for depression. Using resting-state functional connectivity MRI (rs-fcMRI) in a sample of 104 individuals (aged 11-60) at high and low risk for familial depression, we previously reported increased DMN connectivity and reduced DMN-CEN inverse connectivity in high risk individuals. Here, we found that this effect was moderated by self-report measures of R/S importance. Greater R/S importance in the high risk group was associated with decreased DMN connectivity. These results may represent a protective neural adaptation in the DMN of individuals at high risk for depression, and may have implications for other meditation-based therapies for depression. Published by Elsevier Ireland Ltd.

  8. The relative importance of social media for accessing, finding, and engaging with news

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Kleis; Schrøder, Kim Christian

    2014-01-01

    , but also important country-to-country differences, in particular in terms of how widespread the more active and participatory forms of media use are. Surprisingly, these differences do not correspond to differences in levels of internet use, suggesting that more than mere availability shapes the role...

  9. 77 FR 66662 - Generalized System of Preferences (GSP): Import Statistics Relating to Competitive Need Limitations

    Science.gov (United States)

    2012-11-06

    ... into effect. Exclusions for exceeding a CNL will be based on full 2012 calendar-year import statistics...--Ferrosilicon containing between 55% and 80% of silicon (Russia) 2106.90.99--Miscellaneous food preparations not canned or frozen (Thailand) 9506.70.40--Ice skates w/footwear permanently attached (Thailand) The list...

  10. OPACITY BROADENING OF {sup 13}CO LINEWIDTHS AND ITS EFFECT ON THE VARIANCE-SONIC MACH NUMBER RELATION

    Energy Technology Data Exchange (ETDEWEB)

    Correia, C.; De Medeiros, J. R. [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, 59072-970 (Brazil); Burkhart, B.; Lazarian, A. [Astronomy Department, University of Wisconsin, Madison, 475 North Charter Street, WI 53711 (United States); Ossenkopf, V.; Stutzki, J. [Physikalisches Institut der Universität zu Köln, Zülpicher Strasse 77, D-50937 Köln (Germany); Kainulainen, J. [Max-Planck-Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); Kowal, G., E-mail: caioftc@dfte.ufrn.br [Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Universidade de São Paulo, 05508-090 (Brazil)

    2014-04-10

    We study how the estimation of the sonic Mach number (M{sub s} ) from {sup 13}CO linewidths relates to the actual three-dimensional sonic Mach number. For this purpose we analyze MHD simulations that include post-processing to take radiative transfer effects into account. As expected, we find very good agreement between the linewidth estimated sonic Mach number and the actual sonic Mach number of the simulations for optically thin tracers. However, we find that opacity broadening causes M{sub s} to be overestimated by a factor of ≈1.16-1.3 when calculated from optically thick {sup 13}CO lines. We also find that there is a dependence on the magnetic field: super-Alfvénic turbulence shows increased line broadening compared with sub-Alfvénic turbulence for all values of optical depth for supersonic turbulence. Our results have implications for the observationally derived sonic Mach number-density standard deviation (σ{sub ρ/(ρ)}) relationship, σ{sub ρ/〈ρ〉}{sup 2}=b{sup 2}M{sub s}{sup 2}, and the related column density standard deviation (σ {sub N/(N)}) sonic Mach number relationship. In particular, we find that the parameter b, as an indicator of solenoidal versus compressive driving, will be underestimated as a result of opacity broadening. We compare the σ {sub N/(N)}-M{sub s} relation derived from synthetic dust extinction maps and {sup 13}CO linewidths with recent observational studies and find that solenoidally driven MHD turbulence simulations have values of σ {sub N/(N)}which are lower than real molecular clouds. This may be due to the influence of self-gravity which should be included in simulations of molecular cloud dynamics.

  11. Determining the relative importance of figures in journal articles to find representative images

    Science.gov (United States)

    Müller, Henning; Foncubierta-Rodríguez, Antonio; Lin, Chang; Eggel, Ivan

    2013-03-01

    When physicians are searching for articles in the medical literature, images of the articles can help determining relevance of the article content for a specific information need. The visual image representation can be an advantage in effectiveness (quality of found articles) and also in efficiency (speed of determining relevance or irrelevance) as many articles can likely be excluded much quicker by looking at a few representative images. In domains such as medical information retrieval, allowing to determine relevance quickly and accurately is an important criterion. This becomes even more important when small interfaces are used as it is frequently the case on mobile phones and tablets to access scientific data whenever information needs arise. In scientific articles many figures are used and particularly in the biomedical literature only a subset may be relevant for determining the relevance of a specific article to an information need. In many cases clinical images can be seen as more important for visual appearance than graphs or histograms that require looking at the context for interpretation. To get a clearer idea of image relevance in articles, a user test with a physician was performed who classified images of biomedical research articles into categories of importance that can subsequently be used to evaluate algorithms that automatically select images as representative examples. The manual sorting of images of 50 journal articles of BioMedCentral with each containing more than 8 figures by importance also allows to derive several rules that determine how to choose images and how to develop algorithms for choosing the most representative images of specific texts. This article describes the user tests and can be a first important step to evaluate automatic tools to select representative images for representing articles and potentially also images in other contexts, for example when representing patient records or other medical concepts when selecting

  12. Two important safety-related verification tests in the design of Qinshan NPP 600 MWe reactor

    International Nuclear Information System (INIS)

    Li Pengzhou; Li Tianyong; Yu Danping; Sun Lei

    2005-01-01

    This paper summarizes two most important verification tests performed in the design of reactor of Qinshan NPP Phase II: seismic qualification test of control rod drive line (CRDL), flow-induced vibration test of reactor internals both in 1:5 scaled model and on-site measurement during heat function testing (HFT). Both qualification tests proved that the structural design of the reactor has large safety margin. (authors)

  13. The relative importance of mass and wind data in the FGGE observing system

    Science.gov (United States)

    Kalnay, E.; Jusem, J. C.; Pfaendtner, J.

    1986-01-01

    The use of mass and wind data in numerical weather prediction is examined. The applicability of the mass and wind data on the skill of numerical weather prediction is evaluated by real data assimilation experiments using the the NASA/Goddard Laboratory for Atmospheres analysis/forecast system of Baker (1983) and Kalnay et al. (1983). It is observed that the wind observations are important for small scales and in the tropics and that the wind observations are more accurate than mass observations.

  14. Staff perception of relative importance of quality dimensions for patients at tertiary public services in oman.

    Science.gov (United States)

    Alrashdi, Ismail; Al Qasmi, Ahmed

    2012-09-01

    This research attempted to explore the public healthcare providers understanding the quality dimensions and patient priorities in Oman. It also addresses the issue of risks confronting health professionals in management without "a customer focused" approach. A descriptive study was carried out using a self-administered questionnaire distributed around two tertiary public hospitals. A total of 838 respondents from several specialties and levels of hierarchy participated in the study. The data was analyzed to compare the perception of two groups; the group of junior and frontline staff, as well as of managers and senior staff involved in management. The results showed that 61% of the junior and frontline staff, and 68.3% of the senior staff and managers think that cure or improvement in overall health is the single most important quality dimension in healthcare. Both groups perceive that technical dimensions have greater importance (to patients) over interpersonal aspects such as communication with the exception of dignity and respect. There was no significant difference between the perception of the managers and senior staff vis-à-vis the perception of junior and frontline staff on the importance of technical dimensions and the interpersonal aspects of service quality. Despite the proven contribution of empathy to patient satisfaction, it was ranked by both groups as the least important among the dimensions examined. The findings of this research are therefore informative of the need to implement strategies that deal effectively with such attitudes and create the platform and programs that reinforce the culture of good quality service amongst healthcare providers, managers in particular, and to improve patient satisfaction.

  15. The effect of fasting on the important molecular mechanisms related to cancer treatment

    OpenAIRE

    Vahideh Keyvani; Mohammad Amin Kerachian

    2014-01-01

    Fasting does have remarkable benefits in the treatment of cancer and another diseases such as metabolic syndrome, diabetes, and a multitude of other chronic diseases. It has been determined that fasting could play an important role during cancer treatment and progression via the regulation of insulin-like growth factor-1 (IGF-1) as well as other growth factors. Also, it has been shown that fasting would enhance the chemotherapy effect in cancer patients, selectively protects normal cells and ...

  16. LIVEABILITY DIMENSIONS AND ATTRIBUTES: THEIR RELATIVE IMPORTANCE IN THE EYES OF NEIGHBOURHOOD RESIDENTS

    Directory of Open Access Journals (Sweden)

    Ahmad Hariza Hashim

    2010-06-01

    Full Text Available It is important for a neighbourhood to provide a quality and good environment to ensure that inhabitants are able to live their lives in a satisfying way. There have been few attempts to investigate people’s perceptions about the places they currently live, especially what makes their neighbourhoods a good or bad place to live. Thus, this study aims (1 to identify the attributes and the dimensions that residents consider in evaluating the liveability of their neighbourhood and (2 to assess the importance of these attributes and dimensions. A literature review found that four dimensions are used in most studies to understand the liveability issues: social, physical, functional and safe. Sixteen attributes are also identified to be indicators for the four dimensions. The study was conducted in one of the neighbourhoods in the Subang Jaya Municipal Council vicinity, and data were collected using mailed questionnaires. A total of 170 questionnaires were completed and returned, which represented a 57% response rate. Results revealed that residents are most concerned about safety, while social issues are deemed to be the least important factor. Thus, efforts to promote neighbourhood liveability should be focused on ensuring the overall safety of the community by incorporating a design that creates territoriality and allows more surveillance. Neighbourhoods should be maintained to avoid incivilities to reduce the fear of crime and crime itself.

  17. Shell biofilm-associated nitrous oxide production in marine molluscs: processes, precursors and relative importance.

    Science.gov (United States)

    Heisterkamp, Ines M; Schramm, Andreas; Larsen, Lone H; Svenningsen, Nanna B; Lavik, Gaute; de Beer, Dirk; Stief, Peter

    2013-07-01

    Emission of the greenhouse gas nitrous oxide (N2 O) from freshwater and terrestrial invertebrates has exclusively been ascribed to N2 O production by ingested denitrifying bacteria in the anoxic gut of the animals. Our study of marine molluscs now shows that also microbial biofilms on shell surfaces are important sites of N2 O production. The shell biofilms of Mytilus edulis, Littorina littorea and Hinia reticulata contributed 18-94% to the total animal-associated N2 O emission. Nitrification and denitrification were equally important sources of N2 O in shell biofilms as revealed by (15) N-stable isotope experiments with dissected shells. Microsensor measurements confirmed that both nitrification and denitrification can occur in shell biofilms due to a heterogeneous oxygen distribution. Accordingly, ammonium, nitrite and nitrate were important drivers of N2 O production in the shell biofilm of the three mollusc species. Ammonium excretion by the animals was found to be sufficient to sustain N2 O production in the shell biofilm. Apparently, the animals provide a nutrient-enriched microenvironment that stimulates growth and N2 O production of the shell biofilm. This animal-induced stimulation was demonstrated in a long-term microcosm experiment with the snail H. reticulata, where shell biofilms exhibited the highest N2 O emission rates when the animal was still living inside the shell. © 2012 John Wiley & Sons Ltd and Society for Applied Microbiology.

  18. Importance of chemical speciation of iodine in relation to dose estimates from 129I

    International Nuclear Information System (INIS)

    Sheppard, S.C.

    1996-12-01

    Biota live in a chemical milieu and take up elements according to laws of chemistry and physics. Radioactivity is not important to accumulation processes. However, for radionuclides it is almost always the radiological consequences that are important. As such, most discussions and modelling of the processes of distribution, exposure and consequences tend to deal with radionuclides and do not dwell on chemistry. In fact, the chemical aspects of dose estimation are dealt with quite adequately, but usually in an implicit rather than explicit manner. This report discusses the chemistry and chemical speciation of iodine (1) and illustrates how these topics have been implicitly included in biosphere models such as BIOTRAC, the model employed in the assessment of Canada's nuclear fuel waste disposal concept. Iodine is emphasized because 129 I is the dominant contributor to the hypothetical doses estimated. Not all aspects of the behaviour of 1 are implicit in BIOTRAC, but the exceptions are of minor importance. In general, the very broad ranges in parameter values specified for BIOTRAC encompass substantial latitude for the possible effects of chemical behaviour and speciation. Nonetheless, detailed understanding of the behavior of 1 in the environment is essential to the credibility of models such as BIOTRAC. There is substantial room for improved knowledge of the speciation of I, especially in freshwater and soil environments. (author)

  19. Social Support and Attachment to Teachers: Relative Importance and Specificity Among Low-Income Children and Youth of Color

    Science.gov (United States)

    Murray, Christopher; Kosty, Derek; Hauser-McLean, Kristin

    2016-01-01

    A growing number of researchers are examining how teacher-student relationships contribute to child and adolescent development. Much of this work is based on two distinct theoretical perspectives: social support and attachment. The current study investigates the importance of teacher-student relationships from each of these perspectives among…

  20. Relative importance of fuel management, ignition management and weather for area burned: Evidence from five landscape-fire-succession models

    Science.gov (United States)

    Geoffrey J. Cary; Mike D. Flannigan; Robert E. Keane; Ross A. Bradstock; Ian D. Davies; James M. Lenihan; Chao Li; Kimberley A. Logan; Russell A. Parsons

    2009-01-01

    The behaviour of five landscape fire models (CAFE, FIRESCAPE, LAMOS(HS), LANDSUM and SEMLAND) was compared in a standardised modelling experiment. The importance of fuel management approach, fuel management effort, ignition management effort and weather in determining variation in area burned and number of edge pixels burned (a measure of potential impact on assets...

  1. Travel-related imported infections in Europe, EuroTravNet 2009

    NARCIS (Netherlands)

    Odolini, S.; Parola, P.; Gkrania-Klotsas, E.; Caumes, E.; Schlagenhauf, P.; López-Vélez, R.; Burchard, G.-D.; Santos-O'Connor, F.; Weld, L.; von Sonnenburg, F.; Field, V.; de Vries, P.; Jensenius, M.; Loutan, L.; Castelli, F.

    2012-01-01

    The aim of this study was to investigate travel-associated morbidity in European travellers in 2009 in comparison with 2008, with a particular emphasis on emerging infectious diseases with the potential for introduction into Europe. Diagnoses with demographic, clinical and travel-related predictors

  2. The Relative Importance of Psychological Acceptance and Emotional Intelligence to Workplace Well-Being

    Science.gov (United States)

    Donaldson-Feilder, Emma J.; Bond, Frank W.

    2004-01-01

    Psychological acceptance (acceptance) and emotional intelligence (EI) are two relatively new individual characteristics that are hypothesised to affect well-being and performance at work. This study compares both of them, in terms of their ability to predict various well-being outcomes (i.e. general mental health, physical well-being, and job…

  3. Building the Case for Educating Business Leaders on the Importance of Public Relations

    Science.gov (United States)

    Hagan, Linda M.

    2011-01-01

    An organization's well-developed strategic plan and reputation can crumble in minutes if it mishandles key communications, particularly during crises. Today's leaders need to appreciate the value of professional public relations and how it helps organizational effectiveness by building strategic relationships, maintaining a favorable reputation,…

  4. Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis

    NARCIS (Netherlands)

    Lai, Xuelei; Wichers, Harry J.; Soler-Lopez, Montserrat; Dijkstra, Bauke W.

    2017-01-01

    Tyrosinase-related protein 1 (TYRP1) is one of three tyrosinase-like glycoenzymes in human melanocytes that are key to the production of melanin, the compound responsible for the pigmentation of skin, eye, and hair. Difficulties with producing these enzymes in pure form have hampered the

  5. University Faculty and Work-Related Well-Being: The Importance of the Triple Work Profile

    Science.gov (United States)

    Vera, Maria; Salanova, Marisa; Martin, Beatriz

    2010-01-01

    Introduction: The main aim of this study is to test whether different university faculty work profiles (i.e., teaching, research and management) relate with the experience of well-being at work (i.e., burnout, work engagement and intrinsic satisfaction). Method: Hypotheses were tested through a K-means cluster, ANOVA, and confirmatory factor…

  6. How important is the relative balance of fat and carbohydrate as sources of energy in relation to health?

    Science.gov (United States)

    Sanders, Thomas A B

    2016-05-01

    Both the intake of fat, especially saturated trans fatty acids, and refined carbohydrates, particularly sugar, have been linked to increased risk of obesity, diabetes and CVD. Dietary guidelines are generally similar throughout the world, restrict both intake of SFA and added sugar to no more than 10 and 35 % energy for total fat and recommend 50 % energy from carbohydrates being derived from unrefined cereals, tubers, fruit and vegetables. Current evidence favours partial replacement of SFA with PUFA with regard to risk of CVD. The translation of these macronutrient targets into food-based dietary guidelines is more complex because some high-fat foods play an important part in meeting nutrient requirements as well as influencing the risk of chronic disease. Some of the recent controversies surrounding the significance of sugar and the type of fat in the diet are discussed. Finally, data from a recently published randomised controlled trial are presented to show the impact of following current dietary guidelines on cardiovascular risk and nutrient intake compared with a traditional UK diet.

  7. Relations between Perceived Competence, Importance Ratings, and Self-Worth among African American School-Age Children

    Science.gov (United States)

    Grier, Leslie K.

    2013-01-01

    The purpose of this research was to investigate how domain-specific importance ratings affect relations between perceived competence and self-worth among African American school-age children. Importance ratings have been found to affect the strength of the relationship between perceived competence and self-worth and have implications for…

  8. Relative importance of Farmers’ Characteristics in Predicting their Knowledge about Indigenous Agricultural Practices

    Directory of Open Access Journals (Sweden)

    A. Sakeer Husain

    2017-09-01

    Full Text Available This study was conducted to identify the farmers’ characteristics that act as factors in influencing their knowledge on indigenous agricultural practices. The study was conducted in the state of Kerala among 40 farmers each of ten selected horticultural crops. Step wise regression analysis and multiple linear regression analysis were employed to identify the influencing factors. The study revealed that age, farm power status, innovativeness, rational orientation, communication status, and social participation status positively influence knowledge of farmers on indigenous agricultural practices whereas material status, educational status, and family status were the important characteristics of farmers negatively influencing the knowledge of indigenous practices.

  9. The effect of fasting on the important molecular mechanisms related to cancer treatment

    Directory of Open Access Journals (Sweden)

    Vahideh Keyvani

    2014-11-01

    Full Text Available Fasting does have remarkable benefits in the treatment of cancer and another diseases such as metabolic syndrome, diabetes, and a multitude of other chronic diseases. It has been determined that fasting could play an important role during cancer treatment and progression via the regulation of insulin-like growth factor-1 (IGF-1 as well as other growth factors. Also, it has been shown that fasting would enhance the chemotherapy effect in cancer patients, selectively protects normal cells and organisms from chemotherapy toxicity, while simultaneously sensitizing tumors. In this article, we discuss the benefits of fasting in the treatment of cancer through several different molecular pathways.

  10. The incidence of falls among geriatric outpatients in relation to the number and types of drugs taken

    Directory of Open Access Journals (Sweden)

    Magdalena Sylwia Kamińska

    2016-06-01

    Full Text Available Background . Causes of falls among people over 65 are complex because of age-related involutional changes, comorbidity and polypragmasy that exert negative influence on physical mobility. Objectives . The purpose of this study is to assess the incidence of falls in geriatric outpatients in relation to the number and type of drugs taken. Material and methods . The study involved 304 subjects aged 65–100 years, using ambulatory care services. The mean age of the respondents was 78.6 ± 7.4. Women constituted 77.3% of those analyzed, men – 22.7%. This survey-based study was performed using the Geriatric Environmental Inquiry. Results . A higher number of drugs corresponded with more frequent falls (χ2 test; p 0.05. Gender was proved to influence the number of drugs (χ 2 test; p < 0.05. There was a statistically significant relationship between the number of falls and taking hypotensive, anxiolytic and oral antidiabetic drugs (χ2; p < 0.05. Conclusions . 1. The use of a higher number of drugs, irrespective of their pharmacological group, contributes to a higher number of falls, which may be associated with an interaction between particular drugs or be a consequence of a multitude of diseases predisposing to falls. 2. Polypharmacotherapy is a fall risk factor, however it is difficult to say which pharmacology group, discussed in the study, contributes most to the incidence of falls. 3. It is suggested that geriatric pharmacotherapy should be individualized to minimize the incidence of the iatrogenic geriatric syndrome, which predisposes to falls.

  11. Clonal composition of human ovarian cancer based on copy number analysis reveals a reciprocal relation with oncogenic mutation status.

    Science.gov (United States)

    Sakai, Kazuko; Ukita, Masayo; Schmidt, Jeanette; Wu, Longyang; De Velasco, Marco A; Roter, Alan; Jevons, Luis; Nishio, Kazuto; Mandai, Masaki

    2017-10-01

    Intratumoral heterogeneity of cancer cells remains largely unexplored. Here we investigated the composition of ovarian cancer and its biological relevance. A whole-genome single nucleotide polymorphism array was applied to detect the clonal composition of 24 formalin-fixed, paraffin-embedded samples of human ovarian cancer. Genome-wide segmentation data consisting of the log2 ratio (log2R) and B allele frequency (BAF) were used to calculate an estimate of the clonal composition number (CC number) for each tumor. Somatic mutation profiles of cancer-related genes were also determined for the same 24 samples by next-generation sequencing. The CC number was estimated successfully for 23 of the 24 cancer samples. The mean ± SD value for the CC number was 1.7 ± 1.1 (range of 0-4). A somatic mutation in at least one gene was identified in 22 of the 24 ovarian cancer samples, with the mutations including those in the oncogenes KRAS (29.2%), PIK3CA (12.5%), BRAF (8.3%), FGFR2 (4.2%), and JAK2 (4.2%) as well as those in the tumor suppressor genes TP53 (54.2%), FBXW7 (8.3%), PTEN (4.2%), and RB1 (4.2%). Tumors with one or more oncogenic mutations had a significantly lower CC number than did those without such a mutation (1.0 ± 0.8 versus 2.3 ± 0.9, P = 0.0027), suggesting that cancers with driver oncogene mutations are less heterogeneous than those with other mutations. Our results thus reveal a reciprocal relation between oncogenic mutation status and clonal composition in ovarian cancer using the established method for the estimation of the CC number. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  12. Avoiding Systematic Errors in Isometric Squat-Related Studies without Pre-Familiarization by Using Sufficient Numbers of Trials

    Directory of Open Access Journals (Sweden)

    Pekünlü Ekim

    2014-10-01

    Full Text Available There is no scientific evidence in the literature indicating that maximal isometric strength measures can be assessed within 3 trials. We questioned whether the results of isometric squat-related studies in which maximal isometric squat strength (MISS testing was performed using limited numbers of trials without pre-familiarization might have included systematic errors, especially those resulting from acute learning effects. Forty resistance-trained male participants performed 8 isometric squat trials without pre-familiarization. The highest measures in the first “n” trials (3 ≤ n ≤ 8 of these 8 squats were regarded as MISS obtained using 6 different MISS test methods featuring different numbers of trials (The Best of n Trials Method [BnT]. When B3T and B8T were paired with other methods, high reliability was found between the paired methods in terms of intraclass correlation coefficients (0.93-0.98 and coefficients of variation (3.4-7.0%. The Wilcoxon’s signed rank test indicated that MISS obtained using B3T and B8T were lower (p < 0.001 and higher (p < 0.001, respectively, than those obtained using other methods. The Bland- Altman method revealed a lack of agreement between any of the paired methods. Simulation studies illustrated that increasing the number of trials to 9-10 using a relatively large sample size (i.e., ≥ 24 could be an effective means of obtaining the actual MISS values of the participants. The common use of a limited number of trials in MISS tests without pre-familiarization appears to have no solid scientific base. Our findings suggest that the number of trials should be increased in commonly used MISS tests to avoid learning effect-related systematic errors

  13. Relations between high and low power groups: the importance of legitimacy.

    Science.gov (United States)

    Hornsey, Matthew J; Spears, Russell; Cremers, Iris; Hogg, Michael A

    2003-02-01

    Using a social identity perspective, two experiments examined the effects of power and the legitimacy of power differentials on intergroup bias. In Experiment 1, 125 math-science students were led to believe that they had high or low representation in a university decision-making body relative to social-science students and that this power position was either legitimate or illegitimate. Power did not have an independent effect on bias; rather, members of both high and low power groups showed more bias when the power hierarchy was illegitimate than when it was legitimate. This effect was replicated in Experiment 2 (N = 105). In addition, Experiment 2 showed that groups located within an unfair power hierarchy expected the superordinate power body to be more discriminatory than did those who had legitimately high or low power. The results are discussed in terms of their implications for group relations. Copyright 2003 Society for Personality and Social Psychology, Inc.

  14. The relative importance of different types of rewards for employee motivation and commitment in South Africa

    OpenAIRE

    Aleeshah Nujjoo; Ines Meyer

    2012-01-01

    Orientation: Employees’ perceptions of rewards are related to their affective commitment and intrinsic motivation, which have been associated with staff turnover.Research purpose: The study sought to establish the relationship between intrinsic and different extrinsic rewards with intrinsic motivation and affective commitment.Motivation for the study: South African organisations are grappling with employee retention. Literature shows that employees who are more motivated and committed to ...

  15. Important considerations related to the construction of observation wells in radiation facilities sites: A review research

    International Nuclear Information System (INIS)

    El-Sayed, S. A.; Salem, W. M.; Atta, E. R.

    2012-01-01

    Observation wells in radiation facility sites are considered the main sources of the required subsurface geologic and hydrogeologic data. They are the most important means to detect the radioactive and/or chemical contaminants within the ground water. Also, they are used to observe the groundwater level fluctuations and perform the different aquifer tests to understand the hydraulic properties of aquifers and the behavior of contaminants transportation. This research reviews the necessary considerations and available techniques for constructing the observation wells properly. The review process depends on the international guidelines presented in the literature and the field experience. The proper well completion is essential for the well efficiency and longevity. Three main important topics are considered and discussed briefly in this review. They are the preliminary considerations, the drilling program and the well protection procedures. The preliminary considerations included are the collection of the available geologic and hydrogeologic data and information, selection of drilling method and the legal requirements. The drilling program comprises the site preparation, drilling processes, sampling, well logging, well design, casing components and materials, gravel pack and well development. The well protection procedures include well grout, concrete slab and others requirements. Observation wells should be constructed to a high standard and should be properly maintained and protected to ensure ongoing and reliable data collection

  16. Management competencies in higher education: Perceived job importance in relation to level of training required

    Directory of Open Access Journals (Sweden)

    Ingrid L. Potgieter

    2010-11-01

    Research purpose: The aim of this article is to determine the relationship between a specific set of HOD managerial competencies identified as being important for the job and the level of training required in terms of these competencies. Motivation for the study: Research has provided evidence that HODs are often ill-prepared for their managerial role, which requires the development of specific management competencies to enable them to fulfil their roles effectively. Research design, approach and method: A non-experimental quantitative survey design approach was followed and correlational data analyses were performed. A cross-sectional sample of 41 HODs of 22 departments from various faculties of a higher education institution in Gauteng participated in this study. The Management Competency Inventory (MCI of Visser (2009 was applied as a measure. Main findings: The Pearson product-moment analysis indicated that there is a significant relationship between the competencies indicated as being important for the job and the level of training required. Practical/Managerial implications: Training needs of HODs should be formally assessed and the depth of training required in terms of the identified management competencies should be considered in the design of training programmes. Contributions/Value-add: The information obtained in this study may potentially serve as a foundation for the development of an HOD training programme in the South African higher education environment.

  17. Number conservation is related to children's prefrontal inhibitory control: an fMRI study of a piagetian task.

    Directory of Open Access Journals (Sweden)

    Nicolas Poirel

    Full Text Available Although young children can accurately determine that two rows contain the same number of coins when they are placed in a one-to-one correspondence, children younger than 7 years of age erroneously think that the longer row contains more coins when the coins in one of the rows are spread apart. To demonstrate that prefrontal inhibitory control is necessary to succeed at this task (Piaget's conservation-of-number task, we studied the relationship between the percentage of BOLD signal changes in the brain areas activated in this developmental task and behavioral performance on a Stroop task and a Backward Digit Span task. The level of activation in the right insula/inferior frontal gyrus was selectively related to inhibitory control efficiency (i.e., the Stroop task, whereas the activation in the left intraparietal sulcus (IPS was selectively related to the ability to manipulate numerical information in working memory (i.e., the Backward Digit Span task. Taken together, the results indicate that to acquire number conservation, children's brains must not only activate the reversibility of cognitive operations (supported by the IPS but also inhibit a misleading length-equal-number strategy (supported by the right insula/inferior frontal gyrus.

  18. Comprehension of verb number morphemes in Czech children: Singular and plural show different relations to age and vocabulary

    Czech Academy of Sciences Publication Activity Database

    Smolík, Filip; Bláhová, Veronika

    2017-01-01

    Roč. 37, č. 1 (2017), s. 42-57 ISSN 0142-7237 R&D Projects: GA ČR GA13-26779S Institutional support: RVO:68081740 Keywords : comprehension * grammatical agreement * grammatical number * morphology * picture-pointing task * picture-pointing task Subject RIV: AN - Psychology OBOR OECD: Psychology (including human - machine relations) Impact factor: 1.196, year: 2016

  19. The relative importance of habitual and deliberative factors in food consumer behaviour

    DEFF Research Database (Denmark)

    Scholderer, Joachim; Olsen, Svein Ottar; Brunsø, Karen

    2006-01-01

    Rational-choice approaches to consumer behaviour neglect the influence of habitual factors. Previous research outside the food choice area has found that habitual factors tend to dominate when the target behaviour is performed often and in stable contexts, whilst deliberative factors tend......), 0.18 (Denmark), 0.10 (Spain), 0.16 (Netherlands), 0.00 (Poland). Although no general answer may exist to the question whether habitual or deliberative factors are more important in food consumer behaviour, habits appear to dominate behaviour in the domain of seafood consumption....... to dominate when the target behaviour is performed rarely and in unstable contexts. In the food choice area, only little research exists that would allow a similar assessment. As part of the SEAFOODplus project, representative surveys were conducted in Belgium, Denmark, Spain, the Netherlands, and Poland...

  20. The various scenarios leading to WR stars: Their relative importance and the role of mixing

    International Nuclear Information System (INIS)

    Maeder, A.

    1982-01-01

    Over the last 40 years WR stars have been associated with almost all possible evolutionary stages. The author lists 7 scenarios which may be considered as most relevant in view of recent surface abundance determinations. He then considers the importance of mass loss in WR formation and discusses properties of binary WR which suggest that formation is dependent on metallicity and thus galactic location. The role of internal mixing in WR formation is also considered. Mass loss on the MS is shown only to be able to explain a minute fraction of the observed WR stars, whereas internal mixing by shear instability has, for all stellar masses, a larger effect on MS evolution than mass loss. (Auth./C.F.)

  1. Importance of Photobacterium phosphoreum in relation to spoilage of modified atmosphere-packed fish products

    DEFF Research Database (Denmark)

    Dalgaard, Paw; Mejlholm, Ole; Christiansen, T.J.

    1997-01-01

    Occurrence and growth of Photobacterium phosphoreum were studied in 20 experiments with fresh fish from Denmark, Iceland and Greece. The organism was detected in all marine fish species but not in fish from fresh water. Growth of P. phosphoreum to high levels (>10(7) cfu g(-1)) was observed in most...... products and the organism is likely to be of importance for spoilage of several modified atmosphere-packed (MAP) marine fish species when stored at chill temperatures. Some microbiological methods recommended for control of fish products by national and international authorities are inappropriate...... for detection of psychrotolerant and heat-labile micro-organisms like P. phosphoreum. These methods have been used in many previous studies of MAP fish and this could explain why, contrary to the findings in the present study, P. phosphoreum in general was not detected previously in spoiled MAP fish....

  2. FOOD SECURITY IN TUNISIA WITHIN WATER SCARCITY THE RELATIVE IMPORTANCE OF THE MEAT SECTOR

    Directory of Open Access Journals (Sweden)

    Emna Ouertani

    2016-01-01

    Full Text Available This paper analyzes the evolution of food and nutrition security in Tunisia, judges its sustainability within water scarcity conditions and free trade areas, with a specific focus on the meat sector. For such purpose, the FAO indicators and Food Balance Sheets, as well as the Global Food Security Index are all analyzed. Virtual water, owed to meat and cereals for animal feed production and trade, was estimated to expect food security sustainability. Results indicated that Tunisian food and nutrition security (FNS has been improved over the years, but its stability remains vulnerable because of the political and economic risks and the dependence of Tunisia on imported cereals for animal feed due to water scarcity. Tunisian agricultural policy, especially in both sectors of cereals and meat, should be readjusted to guarantee food and nutrition sustainability.

  3. The relative importance of habitual and deliberative factors in food consumer behaviour

    DEFF Research Database (Denmark)

    Scholderer, Joachim; Olsen, Svein Ottar; Brunsø, Karen

    2006-01-01

    Rational-choice approaches to consumer behaviour neglect the influence of habitual factors. Previous research outside the food choice area has found that habitual factors tend to dominate when the target behaviour is performed often and in stable contexts, whilst deliberative factors tend...... to dominate when the target behaviour is performed rarely and in unstable contexts. In the food choice area, only little research exists that would allow a similar assessment. As part of the SEAFOODplus project, representative surveys were conducted in Belgium, Denmark, Spain, the Netherlands, and Poland......), 0.18 (Denmark), 0.10 (Spain), 0.16 (Netherlands), 0.00 (Poland). Although no general answer may exist to the question whether habitual or deliberative factors are more important in food consumer behaviour, habits appear to dominate behaviour in the domain of seafood consumption....

  4. THE RELATIVE IMPORTANCE OF FINANCIAL RATIOS AND NONFINANCIAL VARIABLES IN PREDICTING OF INSOLVENCY

    Directory of Open Access Journals (Sweden)

    Ivica Pervan

    2013-02-01

    Full Text Available One of the most important decisions in every bank is approving loans to firms, which is based on evaluated credit risk and collateral. Namely, it is necessary to evaluate the risk that client will be unable to repay the obligations according to the contract. After Beaver's (1967 and Altman's (1968 seminal papers many authors extended the initial research by changing the methodology, samples, countries, etc. But majority of business failure papers as predictors use financial ratios, while in the real life banks combine financial and nonfinancial variables. In order to test predictive power of nonfinancial variables authors in the paper compare two insolvency prediction models. The first model that used financial rations resulted with classification accuracy of 82.8%, while the combined model with financial and nonfinancial variables resulted with classification accuracy of 88.1%.

  5. The importance of having an appropriate relational data segmentation in ATLAS

    CERN Document Server

    Dimitrov, Gancho; The ATLAS collaboration

    2015-01-01

    In this paper we describe specific technical solutions put in place in various database applications of the ATLAS experiment at LHC where we make use of several partitioning techniques available in Oracle 11g. With the broadly used range partitioning and its option of automatic interval partitioning we add our own logic in PLSQL procedures and scheduler jobs to sustain data sliding windows in order to enforce various data retention policies. We also make use of the new Oracle 11g reference partitioning in the Nightly Build System to achieve uniform data segmentation. However the most challenging issue was to segment the data of the new ATLAS Distributed Data Management system (Rucio), which resulted in tens of thousands list type partitions and sub-partitions. Partition and sub-partition management, index strategy, statistics gathering and queries execution plan stability are important factors when choosing an appropriate physical model for the application data management. The so-far accumulated knowledge and...

  6. The Importance of Postural Control in Relation to Technical Abilities in Small-Sided Soccer Games.

    Science.gov (United States)

    Edis, Çağlar; Vural, Faik; Vurgun, Hikmet

    2016-12-01

    Making assessments regarding postural control and balance is very important for injury prevention in soccer. However, there has been no study that has associated postural control variables with branch-specific technical properties in a game. The aim of the present study was to determine the relationships between variables designating postural control levels and technical performance variables in different (1:1, 2:2 and 3:3) small-sided games (SSGs). Sixteen trained male amateur soccer players volunteered to take part in the study (age 17.2 ± 1.02 years, body height 176.25 ± 0.07 m, body mass 67.67 ± 13.27 kg). Following familiarization sessions, postural control was evaluated using one-leg and both-leg quiet-stance positions by measuring postural sway with a Tekscan HR Mat™ in anterior-posterior and medial-lateral directions. Later, 1:1, 2:2 and 3:3 SSGs were performed at two-day intervals and the technical variables specified for each game were analyzed. A Spearman's rank-order correlation analysis demonstrated the relationship between postural control and soccer-specific technical variables in 1:1 (r-values ranging from 0.582 to 0.776), 2:2 (rvalues ranging from 0.511 to 0.740) and 3:3 (r-values ranging from 0.502 to 0.834) SSGs. In addition, a Wilcoxon signed rank test revealed differences between SSGs in terms of several variables. The results of the study showed that higher postural control levels are among the important variables that affect success in the performance of technical skills under rival pressure and suddenly changing conditions. Therefore, it is recommended that in addition to its use for injury prevention purposes, balance training should be conducted to improve branch-specific technical skills and to increase the levels of their successful performance in a game.

  7. The relative importance of patient-reported barriers to colorectal cancer screening.

    Science.gov (United States)

    Jones, Resa M; Woolf, Steven H; Cunningham, Tina D; Johnson, Robert E; Krist, Alex H; Rothemich, Stephen F; Vernon, Sally W

    2010-05-01

    Colorectal cancer (CRC) screening rates are suboptimal. The most important barriers identified by patients are poorly understood. A comprehensive assessment of barriers to all recommended modalities is needed. In 2007, a questionnaire was mailed to 6100 patients, aged 50-75 years, from 12 family medicine practices in the Virginia Ambulatory Care Outcomes Research Network. People aged 65-75 years and African Americans were oversampled. Patients were asked to rate 19-21 barriers to each of four recommended tests. In 2008, responses were coded on a 5-point scale; higher scores reflected stronger barrier endorsement. The response rate was 55% (n=3357). Approximately 40% of respondents were aged >/=65 years, 30% were African-American, and 73% were adherent to screening. A clinician's failure to suggest screening and not knowing testing was necessary received the highest mean scores as barriers. Financial concerns and misconceptions were also cited. Barrier scores differed depending on whether respondents were never screened, overdue for screening, or adherent to guidelines. The top five barriers for each modality included test-specific barriers (e.g., handling stool, bowel preparation), which often outranked generic barriers to screening. Not knowing testing was necessary was a top barrier for all tests but colonoscopy. Although physician advice and awareness of the need for screening are important, barriers to screening are not homogenous across tests, and test-specific barriers warrant consideration in designing strategies to improve screening rates. Barrier scores differ by screening status, highlighting the need to address prior screening experience. Evidence that patients are more familiar with colonoscopy than with other modalities suggests an opportunity to improve screening rates by educating patients about alternative tests. 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  8. Use of surveillance data on HIV diagnoses with HIV-related symptoms to estimate the number of people living with undiagnosed HIV in need of antiretroviral therapy.

    Science.gov (United States)

    Lodwick, Rebecca K; Nakagawa, Fumiyo; van Sighem, Ard; Sabin, Caroline A; Phillips, Andrew N

    2015-01-01

    It is important to have methods available to estimate the number of people who have undiagnosed HIV and are in need of antiretroviral therapy (ART). The method uses the concept that a predictable level of occurrence of AIDS or other HIV-related clinical symptoms which lead to presentation for care, and hence diagnosis of HIV, arises in undiagnosed people with a given CD4 count. The method requires surveillance data on numbers of new HIV diagnoses with HIV-related symptoms, and the CD4 count at diagnosis. The CD4 count-specific rate at which HIV-related symptoms develop are estimated from cohort data. 95% confidence intervals can be constructed using a simple simulation method. For example, if there were 13 HIV diagnoses with HIV-related symptoms made in one year with CD4 count at diagnosis between 150-199 cells/mm3, then since the CD4 count-specific rate of HIV-related symptoms is estimated as 0.216 per person-year, the estimated number of person years lived in people with undiagnosed HIV with CD4 count 150-199 cells/mm3 is 13/0.216 = 60 (95% confidence interval: 29-100), which is considered an estimate of the number of people living with undiagnosed HIV in this CD4 count stratum. The method is straightforward to implement within a short period once a surveillance system of all new HIV diagnoses, collecting data on HIV-related symptoms at diagnosis, is in place and is most suitable for estimating the number of undiagnosed people with CD4 count HIV-related symptoms at higher CD4 counts. A potential source of bias is under-diagnosis and under-reporting of diagnoses with HIV-related symptoms. Although this method has limitations as with all approaches, it is important for prompting increased efforts to identify undiagnosed people, particularly those with low CD4 count, and for informing levels of unmet need for ART.

  9. Off-site relations and emergency planning or the importance of being earnest

    International Nuclear Information System (INIS)

    Dunkle, M.K.

    1987-01-01

    Emergency planning is and will continue to be a vulnerable spot for the nuclear industry. Emergency planning issues can be reopened at any time during the life of the plant and this represents a threat that continues for the life of the plant. The area of planning in which utilities find themselves most vulnerable is off-site relations with the state and local government officials, the public, and even the news media. Utilities face two very basic challenges in developing and maintaining good off-site relations for emergency preparedness: (1) utility managers must understand and be capable of working with the myriad of personalities and dynamics in the emergency preparedness arena. (2) Emergency preparedness is an emotional issue and a technical subject not well understood by the average citizen. The public looks to well-founded emergency plans and strong leaders to effect them. With these, a sound communications strategy, and a good plant record, a utility stands a chance of achieving the real key to success, credibility

  10. Nuisance Flooding and Relative Sea-Level Rise: the Importance of Present-Day Land Motion.

    Science.gov (United States)

    Karegar, Makan A; Dixon, Timothy H; Malservisi, Rocco; Kusche, Jürgen; Engelhart, Simon E

    2017-09-11

    Sea-level rise is beginning to cause increased inundation of many low-lying coastal areas. While most of Earth's coastal areas are at risk, areas that will be affected first are characterized by several additional factors. These include regional oceanographic and meteorological effects and/or land subsidence that cause relative sea level to rise faster than the global average. For catastrophic coastal flooding, when wind-driven storm surge inundates large areas, the relative contribution of sea-level rise to the frequency of these events is difficult to evaluate. For small scale "nuisance flooding," often associated with high tides, recent increases in frequency are more clearly linked to sea-level rise and global warming. While both types of flooding are likely to increase in the future, only nuisance flooding is an early indicator of areas that will eventually experience increased catastrophic flooding and land loss. Here we assess the frequency and location of nuisance flooding along the eastern seaboard of North America. We show that vertical land motion induced by recent anthropogenic activity and glacial isostatic adjustment are contributing factors for increased nuisance flooding. Our results have implications for flood susceptibility, forecasting and mitigation, including management of groundwater extraction from coastal aquifers.

  11. Role of size on the relative importance of fluid dynamic losses in linear cryocoolers

    Science.gov (United States)

    Kirkconnell, Carl; Ghavami, Ali; Ghiaasiaan, S. Mostafa; Perrella, Matthew

    2017-12-01

    Thermodynamic modeling results for a novel small satellite (SmallSat) Stirling Cryocooler, capable of delivering over 200 mW net cooling power at 80 K for less than 6 W DC input power, are used in this paper as the basis for related pulse tube computational fluid dynamics (CFD) analysis. Industry and government requirements for SmallSat infrared sensors are driving the development of ever-more miniaturized cryocooler systems. Such cryocoolers must be extremely compact and lightweight, a challenge met by this research team through operating a Stirling cryocooler at a frequency of approximately 300 Hz. The primary advantage of operating at such a high frequency is that the required compression and expansion swept volumes are reduced relative to linear coolers operating at lower frequencies, which evidently reduces the size of the motor mechanisms and the thermodynamic components. In the case of a pulse tube cryocooler, this includes a reduction in diameter of the pulse tube itself. This unfortunately leads to high boundary layer losses, as the presented results demonstrate. Using a Stirling approach with a mechanical moving expander piston eliminates this small pulse tube loss mechanism, but other challenges are introduced, such as maintaining very tight clearance gaps between moving and stationary elements. This paper focuses on CFD modelling results for a highly miniaturized pulse tube cooler.

  12. The relative importance of the energy problems in North-South relationships

    International Nuclear Information System (INIS)

    Freymond, J.

    1980-01-01

    The article summarises political situations which have influenced the development of electricity in Switzerland, discussed at a Geneva conference on 22 August 1980. The history is briefly related from 1949 (developments in Communist China), 1956 Budapest, Suez, 1968 Prague, Paris, 1973 the Yom Kippur War and 1974 the Middle East Oil Crisis. All these events have, in various ways, lead to pressure on global reserves of recoverable oil. Some figures are quoted for 1977 giving a global regional breakdown of production totalling 260 gigatonnes. More recent studies refer to the Brandlt Commission studies (a Programme for Survival) and the American studies on 'Entering the 21st Century'. These include references to population growth studies, future oil exploration possibilities and the development of nuclear power for electricity production, with suitable safeguards vis-a-vis health hazards and proliferation of nuclear weapons in the Third World. (G.C.)

  13. The importance of gender of patients and general practitioners in relation to treatment practices for overweight

    DEFF Research Database (Denmark)

    Rohde, Jeanett Friis; Hessner, Marie Vik; Lous, Jørgen

    2014-01-01

    BACKGROUND: Several studies suggest that men and women are treated differently for similar disease including diabetes and cardiovascular disease. Differences in attitudes and treatment practices towards men and women with obesity are not well recognized. OBJECTIVE: To investigate the attitudes...... and treatment practices among Danish general practitioners (GPs), in relation to treatment of overweight, while taking gender of both the patients and practitioners into account. DESIGN: Questionnaire inventory covertly examining attitudes and practices among Danish general practitioners towards treatment......: Among general practitioners in Denmark, treatment for weight loss is more often practiced for overweight male than overweight female patients presenting with same symptoms. In addition, hyperlipidemia among overweight males is also more often treated with lipid lowering medicine than hyperlipidemia...

  14. Dynamic hyporheic exchange at intermediate timescales: testing the relative importance of evapotranspiration and flood pulses

    Science.gov (United States)

    Larsen, Laurel G.; Harvey, Judson W.; Maglio, Morgan M.

    2014-01-01

    Hyporheic fluxes influence ecological processes across a continuum of timescales. However, few studies have been able to characterize hyporheic fluxes and residence time distributions (RTDs) over timescales of days to years, during which evapotranspiration (ET) and seasonal flood pulses create unsteady forcing. Here we present a data-driven, particle-tracking piston model that characterizes hyporheic fluxes and RTDs based on measured vertical head differences. We used the model to test the relative influence of ET and seasonal flood pulses in the Everglades (FL, USA), in a manner applicable to other low-energy floodplains or broad, shallow streams. We found that over the multiyear timescale, flood pulses that drive relatively deep (∼1 m) flow paths had the dominant influence on hyporheic fluxes and residence times but that ET effects were discernible at shorter timescales (weeks to months) as a break in RTDs. Cumulative RTDs on either side of the break were generally well represented by lognormal functions, except for when ET was strong and none of the standard distributions applied to the shorter timescale. At the monthly timescale, ET increased hyporheic fluxes by 1–2 orders of magnitude; it also decreased 6 year mean residence times by 53–87%. Long, slow flow paths driven by flood pulses increased 6 year hyporheic fluxes by another 1–2 orders of magnitude, to a level comparable to that induced over the short term by shear flow in streams. Results suggest that models of intermediate-timescale processes should include at least two-storage zones with different RTDs, and that supporting field data collection occur over 3–4 years.

  15. Know your public: the importance of the EMS provider in community and media relations.

    Science.gov (United States)

    Silvester, A

    1997-10-01

    In the hundreds, and even the thousands, of hours that are spent in EMS training, none of the time is dedicated to community relations and public information. You have learned how to provide a service, but not how to sell the product. We relate to stories about physicians who were unsuccessful because of a poor "bedside manner." The patient's perception of you has very little to do with your score on the final exam or the terminology used as you explain an illness. You are judged by the same rules by which store clerks, telephone operators, waitresses and all others in the field of public service are gauged everyday. You may never do great things, but you can do small things in a great way. Just calling 911 is not enough to save a life. The very idea that we can get everywhere in the nick of time to snatch victims from the jaws of death is a fallacy. You most be concerned with the training provided for the lay public as you are with your own continuing education. There is no better way to make your service more effective than to train your entire community to save lives. There are many reasons why you should know how to deal with the media. A strong relationship can be formed simply by knowing how to make their job easier. Following the golden rules for news releases and interviews help us all appear more professional. The career of an EMT is in metamorphosis. You have been accepted by the patients you served and your fellow members of the medical community. Now you must continue to evolve as practitioners; your skills must change to meet the demands of modern medicine, and your knowledge base must continue to increase as new information becomes available. The one thing that must remain the same is your total commitment to patient care.

  16. Ethnomedicinal knowledge and relative importance of indigenous medicinal plants of Cholistan desert, Punjab Province, Pakistan.

    Science.gov (United States)

    Ahmed, Nadeem; Mahmood, Adeel; Tahir, S S; Bano, Asghari; Malik, Riffat Naseem; Hassan, Seema; Ashraf, Aisha

    2014-09-11

    Ethnomedicinal studies are significant for the discovery of new crude drugs from indigenous reported medicinal plants. The current study aimed to report the indigenous medicinal knowledge of plants and herbal remedies used as folk medicines in Cholistan desert, Punjab Province, Pakistan. Rapid appraisal approach (RAA), semi-structured interviews, group meetings with herbalists, landowners and local people having awareness about the medicinal action of plants were employed to collect the data. This study reports 70 medicinal plants belonging to 27 families that were disseminated among 60 different genera and Poaceae was the predominant family over others with 13 reported medicinal plants. Among plant parts, leaves were the dominant over others with 26.4% used in herbal preparations followed by the stem (25.2%), fruit (21.5%), flower (16.3%), seed (6.5%), bark and pod (02%). Haloxylon recurvum exhibited the highest use vale (UV) 0.83 while least UV was exhibited by Mollugo cerviana that was 0.16. Important medicinal plants, reported in this study have been screened for phytochemical and pharmaceutical activities in different parts of the globe. It is recommended that reported medicinal plants having potent action for cancer and hepatitis must be screened for pharmacological activities. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. The relative importance of different types of rewards for employee motivation and commitment in South Africa

    Directory of Open Access Journals (Sweden)

    Aleeshah Nujjoo

    2012-11-01

    Research purpose: The study sought to establish the relationship between intrinsic and different extrinsic rewards with intrinsic motivation and affective commitment. Motivation for the study: South African organisations are grappling with employee retention. Literature shows that employees who are more motivated and committed to their organisation are less likely to quit. Rewards management strategies serve to create a motivated and committed workforce. Using the correct types of rewards can thus provide a competitive advantage. Research design, approach and method: A cross-sectional, correlational study was conducted. Questionnaire data of 399 South African employees were analysed using bivariate correlations and multiple regression. Main findings: Three main findings emerged. Firstly, there is a relationship between all types of rewards investigated and the two outcome variables. Secondly, this relationship is stronger for intrinsic than for extrinsic rewards and thirdly, monetary rewards do not account for the variance in intrinsic motivation above that of non-monetary rewards. Practical/managerial implications: Rewards management strategies should focus on job characteristics and designs to increase staff intrinsic rewards and include non-monetary rewards, such as supportive leadership, to encourage employees’ intrinsic motivation and affective commitment. Contribution/value-add: This research demonstrated the important role different rewards, particularly intrinsic non-monetary rewards, play in creating a committed and motivated workforce. The insights gained from this study can promote organisational effectiveness. Suggestions of how to expand on and refine the current study are addressed.

  18. Relative importance of moisture migration and amylopectin retrogradation for pound cake crumb firming.

    Science.gov (United States)

    Luyts, A; Wilderjans, E; Van Haesendonck, I; Brijs, K; Courtin, C M; Delcour, J A

    2013-12-15

    Moisture migration largely impacts cake crumb firmness during storage at ambient temperature. To study the importance of phenomena other than crumb to crust moisture migration and to exclude moisture and temperature gradients during baking, crustless cakes were baked using an electrical resistance oven (ERO). Cake crumb firming was evaluated by texture analysis. First, ERO cakes with properties similar to those baked conventionally were produced. Cake batter moisture content (MC) was adjusted to ensure complete starch gelatinisation in the baking process. In cakes baked conventionally, most of the increase in crumb firmness during storage was caused by moisture migration. Proton nuclear magnetic resonance ((1)H NMR) showed that the population containing protons of crystalline starch grew during cake storage. These and differential scanning calorimetry (DSC) data pointed to only limited amylopectin retrogradation. The limited increase in amylopectin retrogradation during cake storage cannot solely account for the significant firming of ERO cakes and, hence, other phenomena are involved in cake firming. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Comparisons of Organic Carbon Analyzers and Related Importance to Water Quality Assessments

    Directory of Open Access Journals (Sweden)

    Murage Ngatia

    2007-05-01

    Full Text Available This study tested whether analyzers using different methods were equally capable of measuring organic carbon in diverse environmental water samples from California’s Sacramento/San Joaquin Delta and its watersheds. The study also evaluated whether the different instruments might provide differing organic carbon concentration measurements, which could in turn trigger (or not a regulatory requirement for enhanced coagulation at a water treatment plant. In Phase 1, samples were collected in eight monthly events at five stations associated with California’s State Water Project and analyzed using three high temperature combustion and three chemical oxidation instruments. Significant differences between instruments occurred in only 20% of the analyses. However, 80% of the observed differences were attributed to one combustion instrument that reported higher values compared to the other instruments. In Phase 2, four certified standards were analyzed with nine instruments. Results suggested that the main contributor of the observed differences was some instruments’ inability to remove inorganic carbon, an important step in the analytical process. There were no significant differences in the frequencies at which different instruments would have prescribed enhanced coagulation at a water treatment plant. We concluded that properly operating instruments using any of the standard methods were equally capable of analyzing the diverse concentration levels of organic carbon in the Delta.

  20. Situational Strength Cues from Social Sources at Work: Relative Importance and Mediated Effects.

    Science.gov (United States)

    Alaybek, Balca; Dalal, Reeshad S; Sheng, Zitong; Morris, Alexander G; Tomassetti, Alan J; Holland, Samantha J

    2017-01-01

    Situational strength is considered one of the most important situational forces at work because it can attenuate the personality-performance relationship. Although organizational scholars have studied the consequences of situational strength, they have paid little attention to its antecedents. To address this gap, the current study focused on situational strength cues from different social sources as antecedents of overall situational strength at work. Specifically, we examined how employees combine situational strength cues emanating from three social sources (i.e., coworkers, the immediate supervisor, and top management). Based on field theory, we hypothesized that the effect of situational strength from coworkers and immediate supervisors (i.e., proximal sources of situational strength) on employees' perceptions of overall situational strength on the job would be greater than the effect of situational strength from the top management (i.e., the distal source of situational strength). We also hypothesized that the effect of situational strength from the distal source would be mediated by the effects of situational strength from the proximal sources. Data from 363 full-time employees were collected at two time points with a cross-lagged panel design. The former hypothesis was supported for one of the two situational strength facets studied. The latter hypothesis was fully supported.

  1. The importance of having an appropriate relational data segmentation in ATLAS

    Science.gov (United States)

    Dimitrov, G.

    2015-12-01

    In this paper we describe specific technical solutions put in place in various database applications of the ATLAS experiment at LHC where we make use of several partitioning techniques available in Oracle 11g. With the broadly used range partitioning and its option of automatic interval partitioning we add our own logic in PLSQL procedures and scheduler jobs to sustain data sliding windows in order to enforce various data retention policies. We also make use of the new Oracle 11g reference partitioning in the Nightly Build System to achieve uniform data segmentation. However the most challenging issue was to segment the data of the new ATLAS Distributed Data Management system (Rucio), which resulted in tens of thousands list type partitions and sub-partitions. Partition and sub-partition management, index strategy, statistics gathering and queries execution plan stability are important factors when choosing an appropriate physical model for the application data management. The so-far accumulated knowledge and analysis on the new Oracle 12c version features that could be beneficial will be shared with the audience.

  2. Situational Strength Cues from Social Sources at Work: Relative Importance and Mediated Effects

    Directory of Open Access Journals (Sweden)

    Balca Alaybek

    2017-09-01

    Full Text Available Situational strength is considered one of the most important situational forces at work because it can attenuate the personality–performance relationship. Although organizational scholars have studied the consequences of situational strength, they have paid little attention to its antecedents. To address this gap, the current study focused on situational strength cues from different social sources as antecedents of overall situational strength at work. Specifically, we examined how employees combine situational strength cues emanating from three social sources (i.e., coworkers, the immediate supervisor, and top management. Based on field theory, we hypothesized that the effect of situational strength from coworkers and immediate supervisors (i.e., proximal sources of situational strength on employees' perceptions of overall situational strength on the job would be greater than the effect of situational strength from the top management (i.e., the distal source of situational strength. We also hypothesized that the effect of situational strength from the distal source would be mediated by the effects of situational strength from the proximal sources. Data from 363 full-time employees were collected at two time points with a cross-lagged panel design. The former hypothesis was supported for one of the two situational strength facets studied. The latter hypothesis was fully supported.

  3. The importance of having an appropriate relational data segmentation in ATLAS

    International Nuclear Information System (INIS)

    Dimitrov, G

    2015-01-01

    In this paper we describe specific technical solutions put in place in various database applications of the ATLAS experiment at LHC where we make use of several partitioning techniques available in Oracle 11g. With the broadly used range partitioning and its option of automatic interval partitioning we add our own logic in PLSQL procedures and scheduler jobs to sustain data sliding windows in order to enforce various data retention policies. We also make use of the new Oracle 11g reference partitioning in the Nightly Build System to achieve uniform data segmentation. However the most challenging issue was to segment the data of the new ATLAS Distributed Data Management system (Rucio), which resulted in tens of thousands list type partitions and sub-partitions. Partition and sub-partition management, index strategy, statistics gathering and queries execution plan stability are important factors when choosing an appropriate physical model for the application data management. The so-far accumulated knowledge and analysis on the new Oracle 12c version features that could be beneficial will be shared with the audience. (paper)

  4. Enabling Pupils to Conceive Part-Whole Relations of Numbers and Develop Number Sense: Year One of Primary Schools in Malaysia

    Science.gov (United States)

    Sinnakaudan, Santi; Kuldas, Seffetullah; Hashim, Shahabuddin; Ghazali, Munirah

    2016-01-01

    This review examines reasons for Malaysian pupils' underperformance in solving mathematics problems that demand numerical estimation and mental computation. Their underdeveloped number sense appears to be the major reason. According to the Ministry of Education, the national mathematics curriculum is unlikely to account for this underachievement.…

  5. Belonging and doing: important factors for satisfaction with sexual relations as perceived by people with persistent mental illness.

    Science.gov (United States)

    Eklund, Mona; Ostman, Margareta

    2010-07-01

    It is increasingly acknowledged that satisfaction with sexual relations forms an important aspect of people's lives, but little is known of factors associated with this phenomenon among people with mental illness. This study aimed to investigate how demographic, social, clinical, and health-related factors were related to satisfaction with sexual relations. Patients with persistent mental illness (N = 103), recruited from an outpatient unit, were assessed regarding the target variables. No clinical variable, and only one demographic factor, namely being a cohabitant, was found to be important to satisfaction with sexual relations. Several social factors, pertaining to how everyday occupations were valued and how the social network was perceived, were shown to be of importance. General quality of life, but not self-rated health or interviewer-assessed psychopathology, was also important for satisfaction with sexual relations. A multivariate analysis showed that the most significant factor for satisfaction with sexual relations was how everyday activities were valued, and being a cohabitant explained some additional variation. Previous research indicates that the mental health care services largely neglect sexual problems among people with mental illness, and the findings may provide additional knowledge that may be used in the support of this target group.

  6. On the relative importance of bending and compression in cervical spine bilateral facet dislocation.

    Science.gov (United States)

    Nightingale, Roger W; Bass, Cameron R; Myers, Barry S

    2018-03-08

    Cervical bilateral facet dislocations are among the most devastating spine injuries in terms of likelihood of severe neurological sequelae. More than half of patients with tetraparesis had sustained some form of bilateral facet fracture dislocation. They can occur at any level of the sub-axial cervical spine, but predominate between C5 and C7. The mechanism of these injuries has long been thought to be forceful flexion of the chin towards the chest. This "hyperflexion" hypothesis comports well with intuition and it has become dogma in the clinical literature. However, biomechanical studies of the human cervical spine have had little success in producing this clinically common and devastating injury in a flexion mode of loading. The purpose of this manuscript is to review the clinical and engineering literature on the biomechanics of bilateral facet dislocations and to describe the mechanical reasons for the causal role of compression, and the limited role of head flexion, in producing bilateral facet dislocations. Bilateral facet dislocations have only been produced in experiments where compression is the primary loading mode. To date, no biomechanical study has produced bilateral facet dislocations in a whole spine by bending. Yet the notion that it is primarily a hyper-flexion injury persists in the clinical literature. Compression and compressive buckling are the primary causes of bilateral facet dislocations. It is important to stop using the hyper-flexion nomenclature to describe this class of cervical spines injuries because it may have a detrimental effect on designs for injury prevention. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Relapse of imported Plasmodium vivax malaria is related to primaquine dose: a retrospective study

    Directory of Open Access Journals (Sweden)

    Townell Nicola

    2012-06-01

    Full Text Available Abstract Background Relapsing Plasmodium vivax infection results in significant morbidity for the individual and is a key factor in transmission. Primaquine remains the only licensed drug for prevention of relapse. To minimize relapse rates, treatment guidelines have recently been revised to recommend an increased primaquine dose, aiming to achieve a cumulative dose of ≥6 mg/kg, i.e. ≥420 mg in a 70 kg patient. The aims of this study were to characterize the epidemiology of P. vivax infection imported into Queensland Australia, to determine the rates of relapse, to investigate the use of primaquine therapy, and its efficacy in the prevention of relapse. Methods A retrospective study was undertaken of laboratory confirmed P. vivax infection presenting to the two major tertiary hospitals in Queensland, Australia between January 1999 and January 2011. Primaquine dosing was classified as no dose, low dose ( Results Twenty relapses occurred following 151 primary episodes of P. vivax infection (13.2%. Relapses were confirmed among 3/21 (14.2%, 9/50 (18.0%, 1/54 (1.9% and 7/18 (38.9% of patients administered no dose, low dose, high dose and unknown primaquine dose respectively. High dose primaquine therapy was associated with a significantly lower rate of relapse compared to patients who were prescribed low dose therapy (OR 11.6, 95% CI 1.5-519, p = 0.005. Conclusions Relapse of P. vivax infection is more likely in patients who received low dose primaquine therapy. This study supports the recommendations that high dose primaquine therapy is necessary to minimize relapse of P. vivax malaria.

  8. The importance of age-related decline in forest NPP for modeling regional carbon balances.

    Science.gov (United States)

    Zaehle, Sönke; Sitch, Stephen; Prentice, I Colin; Liski, Jari; Cramer, Wolfgang; Erhard, Markus; Hickler, Thomas; Smith, Benjamin

    2006-08-01

    We show the implications of the commonly observed age-related decline in aboveground productivity of forests, and hence forest age structure, on the carbon dynamics of European forests in response to historical changes in environmental conditions. Size-dependent carbon allocation in trees to counteract increasing hydraulic resistance with tree height has been hypothesized to be responsible for this decline. Incorporated into a global terrestrial biosphere model (the Lund-Potsdam-Jena model, LPJ), this hypothesis improves the simulated increase in biomass with stand age. Application of the advanced model, including a generic representation of forest management in even-aged stands, for 77 European provinces shows that model-based estimates of biomass development with age compare favorably with inventory-based estimates for different tree species. Model estimates of biomass densities on province and country levels, and trends in growth increment along an annual mean temperature gradient are in broad agreement with inventory data. However, the level of agreement between modeled and inventory-based estimates varies markedly between countries and provinces. The model is able to reproduce the present-day age structure of forests and the ratio of biomass removals to increment on a European scale based on observed changes in climate, atmospheric CO2 concentration, forest area, and wood demand between 1948 and 2000. Vegetation in European forests is modeled to sequester carbon at a rate of 100 Tg C/yr, which corresponds well to forest inventory-based estimates.

  9. The relative importance of genetic and environmental effects for the early stages of thyroid autoimmunity

    DEFF Research Database (Denmark)

    Hansen, Pia S; Brix, Thomas H; Iachine, Ivan

    2006-01-01

    OBJECTIVE: In euthyroid individuals, autoantibodies to thyroid peroxidase (TPOab) and thyroglobulin (Tgab) are regarded as early markers of thyroid autoimmunity. Family and twin studies suggest that development of thyroid autoantibodies in first-degree relatives of patients with autoimmune thyroi....... The analyses suggest that it is the same set of genes that operate in males and females. However, complex mechanisms such as dominance and/or epistasis may be involved....... concordance and intraclass correlations were consistently higher for MZ than for DZ twin pairs indicating genetic influence. Genetic components (with 95% confidence intervals) accounted for 73% (46-89%) of the liability of being thyroid antibody positive. Adjusting for covariates (age, TSH and others......), the estimate for genetic influence on serum TPOab concentrations was 61% (49-70%) in males and 72% (64-79%) in females. For serum Tgab concentrations, the estimates were 39% (24-51%) and 75% (66-81%) respectively. CONCLUSIONS: Early markers of thyroid autoimmunity appear to be under strong genetic influence...

  10. HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy

    Science.gov (United States)

    Smeets, Cleo J. L. M.; Franklin, Sophie A.; Bondulich, Marie K.; Jolinon, Nelly; Muller, Thomas; Ahmed, Mhoriam; Dick, James R. T.; Piotrowska, Izabela; Greensmith, Linda; Smolenski, Ryszard T.; Bates, Gillian P.

    2015-01-01

    Skeletal muscle remodelling and contractile dysfunction occur through both acute and chronic disease processes. These include the accumulation of insoluble aggregates of misfolded amyloid proteins that is a pathological feature of Huntington’s disease (HD). While HD has been described primarily as a neurological disease, HD patients’ exhibit pronounced skeletal muscle atrophy. Given that huntingtin is a ubiquitously expressed protein, skeletal muscle fibres may be at risk of a cell autonomous HD-related dysfunction. However the mechanism leading to skeletal muscle abnormalities in the clinical and pre-clinical HD settings remains unknown. To unravel this mechanism, we employed the R6/2 transgenic and HdhQ150 knock-in mouse models of HD. We found that symptomatic animals developed a progressive impairment of the contractile characteristics of the hind limb muscles tibialis anterior (TA) and extensor digitorum longus (EDL), accompanied by a significant loss of motor units in the EDL. In symptomatic animals, these pronounced functional changes were accompanied by an aberrant deregulation of contractile protein transcripts and their up-stream transcriptional regulators. In addition, HD mouse models develop a significant reduction in muscle force, possibly as a result of a deterioration in energy metabolism and decreased oxidation that is accompanied by the re-expression of the HDAC4-DACH2-myogenin axis. These results show that muscle dysfunction is a key pathological feature of HD. PMID:25748626

  11. Calcitonin gene related family peptides: importance in normal placental and fetal development.

    Science.gov (United States)

    Yallampalli, Chandra; Chauhan, Madhu; Endsley, Janice; Sathishkumar, Kunju

    2014-01-01

    Synchronized molecular and cellular events occur between the uterus and the implanting embryo to facilitate successful pregnancy outcome. Nevertheless, the molecular signaling network that coordinates strategies for successful decidualization, placentation and fetal growth are not well understood. The discovery of calcitonin/calcitonin gene-related peptides (CT/CGRP) highlighted new signaling mediators in various physiological processes, including reproduction. It is known that CGRP family peptides including CGRP, adrenomedulin and intermedin play regulatory functions during implantation, trophoblast proliferation and invasion, and fetal organogenesis. In addition, all the CGRP family peptides and their receptor components are found to be expressed in decidual, placental and fetal tissues. Additionally, plasma levels of peptides of the CGRP family were found to fluctuate during normal gestation and to induce placental cellular differentiation, proliferation, and critical hormone signaling. Moreover, aberrant signaling of these CGRP family peptides during gestation has been associated with pregnancy disorders. It indicates the existence of a possible regulatory role for these molecules during decidualization and placentation processes, which are known to be particularly vulnerable. In this review, the influence of the CGRP family peptides in these critical processes is explored and discussed.

  12. Important sources and chemical species of ambient fine particles related to adverse health effects

    Science.gov (United States)

    Heo, J.

    2017-12-01

    Although many epidemiological studies have reported that exposure to ambient fine particulate matter (PM2.5) has been linked to increases in mortality and mobidity health outcomes, the key question of which chemical species and sources of PM2.5 are most harmful to public health remains unanswered in the air pollution research area. This study was designed to address the key question with evaluating the risks of exposure to chemical species and source-specific PM2.5 mass on morbidity. Hourly measurements of PM2.5 mass and its major chemical species, including organic carbon, elemental carbon, ions, and trace elements, were observed from January 1 to December 31, 2013 at four of the PM2.5 supersites in urban environments in Korea and the reuslts were used in a positive matrix factorization to estimate source contributions to PM2.5 mass. Nine sources, including secondary sulfate, secondary nitrate, mobile, biomass burning, roadway emission, industry, oil combustion, soil, and aged sea salt, were identified and secondary inorganic aerosol factors (i.e. secondary sulfalte, and secondary nitrate) were the dominant sources contributing to 40% of the total PM2.5 mass in the study region. In order to evaluate the risks of exposure to chemical species and sources of PM2.5 on morbidity, emergency room visits for cardivascular disease and respiratory disease were considered. Hourly health outcomes were compared with hourly measurments of the PM2.5 chemical species and sources using a poission generalized linear model incorporating natural splines, as well as time-stratified case-crossover design. The PM2.5 mass and speveral chemical components, such as organic carbon, elemetal carbon, zinc, and potassium, were strongly associated with morbidity. Source-apporitionmened PM2.5 mass derived from biomass burning, and mobile sources, was significantly associated with cardiovascular and respiratory diseases. The findings represent that local combustion may be particularly important

  13. EVALUATION OF THE IMPORTANCE OF BIOCHEMICAL PARAMETERS IN RELATION TO ULTRASONOGRAPHIC FINDING IN ECTOPIC PREGNANCY DIAGNOSIS

    Directory of Open Access Journals (Sweden)

    Dragan Lončar

    2011-09-01

    Full Text Available The implantation of the fertilized egg outside the uterine cavity leads to the development of ectopic pregnancy. The incidence of ectopic pregnancy is 1/100 births. The most common place of ectopic implantation of the fertilized ovum is the oviduct (98% with predilection for the ampullar part of the Fallopian tube. The aim of this study was to determine the predictive importance of beta-hCG and progesterone concentration compared to ultrasonographic finding in the ectopic pregnancy diagnosis.We examined 24 patients with ectopic pregnancies which we divided according to the days of amenorrhea into two groups: the first group with the total of 28 patients from 16–42 days and another group of 8 patients with amenorrhea longer than 42 days. The control group was comprised of 20 patients with vital intrauterine pregnancy, gestational age of 42-52 days. Blood samples for quantitative determination of hormones were collected on three occasions after 48 hours in the forenoon time in the examined and control group of pregnant women. Ultrasonographic examinations of all pregnant women were carried out immediately after blood sampling, with the trans-vaginal approach using "make loop" option, and measurements with an accuracy of 0.1 mm.Mean values for beta-hCG range from 698-1774 mlU/ml in the first group of pregnant women, and in the second group of 1896 mlU/ml to 4410 mlU/ml with a statistically significant difference compared to the values in the control group (p <0.001. The concentration of progesterone in the first group of women ranging from 41-70 nmol/l, and in the second group of 76-94 nmol/l which is also the statistically significant difference compared to the control group (p<0.002. We have shown that ultrasonographic finding with its parameters reliably predicts the values of biochemical parameters both in normal intrauterine pregnancy and in the case of ectopic pregnancy.Embryo viability and implantation place condition the values of

  14. Variable feeding behavior in Orchestoidea tuberculata (Nicolet 1849): Exploring the relative importance of macroalgal traits

    Science.gov (United States)

    Duarte, Cristian; Acuña, Karin; Navarro, Jorge M.; Gómez, Iván; Jaramillo, Eduardo; Quijón, Pedro

    2014-03-01

    The feeding behavior of algal consumers inhabiting sandy beaches and the consequences of this behavior on their performance are poorly understood. Food quality has been shown to influence the food preference of algal consumers. However, food preference can often be altered or subordinated to habitat choice. This study analyzes the feeding behavior (preference and consumption rate), absorption efficiency and growth rates of the talitrid amphipod Orchestoidea tuberculata (Nicolet, 1849) in relation to the nutritional characteristics of two of the most common macroalgae stranded in the Chilean north-central region. Our experiments show that these amphipods prefer Macrocystis integrifolia over Lessonia nigrescens when presented with fresh fragments of both algae simultaneously. However, this preference did not match the performance of the amphipods when reared on diets of a single algal species: in that growth rates were not different. These results suggest that M. integrifolia is not a superior food item compared to L. nigrescens. The lower content of proteins and total organic matter found in M. integrifolia supports this interpretation. The preference of the amphipods for L. nigrescens over M. integrifolia when dry powdered algae of each species were provided (artificial food), suggested that some aspect of the physical structure of these two algae determined food preference. When the amphipods were maintained with each of the algal species in no choice experiments, they consumed 2 times more M. integrifolia, but showed higher absorption efficiency on L. nigrescens. These results suggest that food quantity and not absorption efficiency was used to compensate for the lower nutritional quality of M. integrifolia. The feeding behavior documented in this study differs significantly from that observed in populations of the same species inhabiting southern Chile, cautioning against generalizing results obtained even within a single species. Our results suggest that

  15. Postnatal care for newborns in Bangladesh: The importance of health-related factors and location.

    Science.gov (United States)

    Singh, Kavita; Brodish, Paul; Chowdhury, Mahbub Elahi; Biswas, Taposh Kumar; Kim, Eunsoo Timothy; Godwin, Christine; Moran, Allisyn

    2017-12-01

    Bangladesh achieved Millennium Development Goal 4, a two thirds reduction in under-five mortality from 1990 to 2015. However neonatal mortality remains high, and neonatal deaths now account for 62% of under-five deaths in Bangladesh. The objective of this paper is to understand which newborns in Bangladesh are receiving postnatal care (PNC), a set of interventions with the potential to reduce neonatal mortality. Using data from the Bangladesh Maternal Mortality Survey (BMMS) 2010 we conducted logistic regression analysis to understand what socio-economic and health-related factors were associated with early postnatal care (PNC) by day 2 and PNC by day 7. Key variables studied were maternal complications (during pregnancy, delivery or after delivery) and contact with the health care system (receipt of any antenatal care, place of delivery and type of delivery attendant). Using data from the BMMS 2010 and an Emergency Obstetric and Neonatal Care (EmONC) 2012 needs assessment, we also presented descriptive maps of PNC coverage overlaid with neonatal mortality rates. There were several significant findings from the regression analysis. Newborns of mothers having a skilled delivery were significantly more likely to receive PNC (Day 7: OR = 2.16, 95% confidence interval (CI) 1.81, 2.58; Day 2: OR = 2.11, 95% 95% CI 1.76). Newborns of mothers who reported a complication were also significantly more likely to receive PNC with odds ratios varying between 1.3 and 1.6 for complications at the different points along the continuum of care. Urban residence and greater wealth were also significantly associated with PNC. The maps provided visual images of wide variation in PNC coverage and indicated that districts with the highest PNC coverage, did not necessarily have the lowest neonatal mortality rates. Newborns of mothers who had a skilled delivery or who experienced a complication were more likely to receive PNC than newborns of mothers with a home delivery or who did

  16. Different indicators of socioeconomic status and their relative importance as determinants of health in old age.

    Science.gov (United States)

    Darin-Mattsson, Alexander; Fors, Stefan; Kåreholt, Ingemar

    2017-09-26

    Socioeconomic status has been operationalised in a variety of ways, most commonly as education, social class, or income. In this study, we also use occupational complexity and a SES-index as alternative measures of socioeconomic status. Studies show that in analyses of health inequalities in the general population, the choice of indicators influence the magnitude of the observed inequalities. Less is known about the influence of indicator choice in studies of older adults. The aim of this study is twofold: i) to analyse the impact of the choice of socioeconomic status indicator on the observed health inequalities among older adults, ii) to explore whether different indicators of socioeconomic status are independently associated with health in old age. We combined data from two nationally representative Swedish surveys, providing more than 20 years of follow-up. Average marginal effects were estimated to compare the association between the five indicators of SES, and three late-life health outcomes: mobility limitations, limitations in activities of daily living (ADL), and psychological distress. All socioeconomic status indicators were associated with late-life health; there were only minor differences in the effect sizes. Income was most strongly associated to all indicators of late-life health, the associations remained statistically significant when adjusting for the other indicators. In the fully adjusted models, education contributed to the model fits with 0-3% (depending on the outcome), social class with 0-1%, occupational complexity with 1-8%, and income with 3-18%. Our results indicate overlapping properties between socioeconomic status indicators in relation to late-life health. However, income is associated to late-life health independently of all other variables. Moreover, income did not perform substantially worse than the composite SES-index in capturing health variation. Thus, if the primary objective of including an indicator of socioeconomic

  17. Phase relations in a forced turbulent boundary layer: implications for modelling of high Reynolds number wall turbulence.

    Science.gov (United States)

    Duvvuri, Subrahmanyam; McKeon, Beverley

    2017-03-13

    Phase relations between specific scales in a turbulent boundary layer are studied here by highlighting the associated nonlinear scale interactions in the flow. This is achieved through an experimental technique that allows for targeted forcing of the flow through the use of a dynamic wall perturbation. Two distinct large-scale modes with well-defined spatial and temporal wavenumbers were simultaneously forced in the boundary layer, and the resulting nonlinear response from their direct interactions was isolated from the turbulence signal for the study. This approach advances the traditional studies of large- and small-scale interactions in wall turbulence by focusing on the direct interactions between scales with triadic wavenumber consistency. The results are discussed in the context of modelling high Reynolds number wall turbulence.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).

  18. Relative importance of the determinants of serum levels of 25-hydroxy vitamin D in patients with chronic kidney disease.

    Science.gov (United States)

    Caravaca-Fontán, Fernando; Gonzales-Candia, Boris; Luna, Enrique; Caravaca, Francisco

    The cause of vitamin D deficiency in chronic kidney disease (CKD) is probably multi-factorial; however, the relative importance of each potential determinant is uncertain. To determine factors associated with serum levels of 25-hydroxy vitamin D (25OHD) and their relative importance in a cohort of pre-dialysis CKD patients. Incident patients admitted to a CKD outpatient clinic were included. Those who were receiving vitamin D supplements or anticonvulsants were excluded. In addition to demographic and clinical data, information about outdoor physical activity, season of blood collection, prescription of statins, anti-angiotensin drugs and xanthine-oxidase inhibitors were included as potential determinants. Johnson's relative weights analysis was used to estimate the relative importance of each potential determinant and the results were expressed as percentage contribution to multiple R. The study group consisted of 397 patients, 30 of whom were excluded. The mean serum level of 25OHD was 13.7±7.4ng/ml, and 81% of patients had serum levels lower than 20ng/ml. By multiple linear regression and relative weights analyses, the best determinants of low serum 25OHD levels and their relative importance were: higher proteinuria (28.5%), old age (21.4%), low physical activity (19.4%), female gender (19.3%) and low serum bicarbonate levels (11.4%). Proteinuria and age are the determinants with the highest relative importance for predicting 25OHD levels in CKD patients. Copyright © 2016. Published by Elsevier España, S.L.U.

  19. A simulation study of sample size demonstrated the importance of the number of events per variable to develop prediction models in clustered data

    NARCIS (Netherlands)

    Wynants, L.; Bouwmeester, W.; Moons, K. G. M.; Moerbeek, M.; Timmerman, D.; Van Huffel, S.; Van Calster, B.; Vergouwe, Y.

    2015-01-01

    Objectives: This study aims to investigate the influence of the amount of clustering [intraclass correlation (ICC) = 0%, 5%, or 20%], the number of events per variable (EPV) or candidate predictor (EPV = 5, 10, 20, or 50), and backward variable selection on the performance of prediction models.

  20. The work-related fatal injury study: numbers, rates and trends of work-related fatal injuries in New Zealand 1985-1994.

    Science.gov (United States)

    Feyer, A M; Langley, J; Howard, M; Horsburgh, S; Wright, C; Alsop, J; Cryer, C

    2001-01-26

    To determine the number and rates of work-related fatal injuries by employment status, occupation, industry, age and gender in New Zealand 1985-1994. Potential cases of work-related injury deaths of persons aged 15-84 years were identified from the national electronic mortality data files. Main exclusions were deaths due to suicide and deaths due to motor vehicle crashes. The circumstances of the deaths of each fatal incident meeting inclusion criteria were then reviewed directly from coronial files to determine work-relatedness. The rate of work-related fatal injury in New Zealand was 5.03/100000 workers per year for the study period. There was a significant decline in crude rate over the study period. However, this was in substantial part accounted for by changes in occupation and industry mix. Older workers, male workers, self-employed workers, and particular occupational groups, all had substantially elevated rates. Agricultural and helicopter pilots, forestry workers and fishery workers had the highest rates. Farmers, forestry workers, and fishery workers also had high numbers of deaths, together accounting for nearly 40% of all deaths. This study has demonstrated that work-related fatal injury remains a pressing problem for New Zealand. Several areas in urgent need of prevention efforts were highlighted.

  1. Number-related discrimination and summation by squirrel monkeys (Saimiri sciureus sciureus and S. boliviensus boliviensus) on the basis of the number of sides of polygons.

    Science.gov (United States)

    Terrell, D F; Thomas, R K

    1990-09-01

    In Experiment 1, with the number of sides or angles of irregular polygons as cues, programmed training, and a 90% correct criterion (36 of 40), 2 squirrel monkeys' (Saimiri sciureus sciureus and S. boliviensus boliviensus) best performances were to discriminate heptagons from octagons, a 3rd's best was hexagons from heptagons, and a 4th's best was pentagons from heptagons. In Experiment 2, on most trials 2 polygons on one or both discriminanda had to be summed to determine which discrimination had the total fewer sides. Only 1 monkey met criterion (27 of 30) on the 2 tasks, 6 vs. 8 and 7 vs. 8 sides, but the other 3 performed better than chance on the 6 vs. 8 task. We conclude that previous studies of animals' discrimination of polygons in terms of complexity were minimally relevant to this work, and counting and subitizing were rejected in favor of a prototype-matching process to explain our monkeys' performances.

  2. Copy number variation in VEGF gene as a biomarker of susceptibility to age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Norshakimah Md Bakri

    2018-07-01

    Full Text Available Background: Several studies in various populations have been conducted to determine candidate genes that could contribute to age-related macular degeneration (AMD pathogenesis. Objective: The present study was undertaken to determine the association of high temperature requirement A-1 (HTRA1, vascular endothelial growth factor (VEGF and very-low-density receptor (VLDR genes with wet AMD subjects in Malaysia. Methods: A total of 125 subjects with wet AMD and 120 subjects without AMD from the Malaysian population were selected for this study. Genomic DNA was extracted and copy number variations (CNVs were determined using quantitative real-time Polymerase Chain Reaction (qPCR and comparison between the two groups was done. The demographic characteristics were also recorded. Statistical analysis was carried out using software where a level of P  0.05. Conclusion: Observations of an association between CNVs of VEGF gene and wet AMD have revealed that the CNVs of VEGF gene appears to be a possible contributor to wet AMD subjects in Malaysia. Keywords: Age-related macular degeneration, Copy number variations, VEGF, HTRA1, VLDR genes and Malaysia

  3. What is the relation between number of sessions worked and productivity of radiologists-a pilot study?

    Science.gov (United States)

    Khan, Shah H M; Hedges, William P

    2016-04-01

    Increasing workloads and the current austerity measures are putting UK radiology departments under considerable stress. We need to look at the most efficient ways to manage radiology departments in order to cope with increasing demand. Consequently, a system is needed that can compare productivity between radiologists with different jobs. We measured workload in a UK radiology department and compared the productivities of consultants working different numbers of sessions, which are called programmed activities (PAs), to identify the optimal job plan structure for reporting productivity. Reporting data was gathered from electronic records for 14 consultants working different numbers of PA during the period April 2010-March 2011. These were converted into relative value unit (RVU) scores using a modified RCSI RVU system. Crude and net workloads were calculated for each consultant by dividing their total RVU score by the number of PAs they were contracted for and how many they spent reporting. The consultants reported 118,001 imaging studies. There was statistically significant variation in productivity between consultants working different numbers of PAs on χ (2) analysis (p working 12 PAs were more productive than consultants working 11 PAs, with net workloads of 7636 RVU/PA/year versus net 6146 RVU/PA/year, p working 12 PAs per week are more productive than their colleagues, the reasons why are unclear. We have identified a method that can be developed further to identify efficient working practices in UK radiology departments. However, a UK-specific RVU system would make this productivity analysis more accurate.

  4. The relation of the number of languages spoken to performance in different cognitive abilities in old age.

    Science.gov (United States)

    Ihle, Andreas; Oris, Michel; Fagot, Delphine; Kliegel, Matthias

    2016-12-01

    Findings on the association of speaking different languages with cognitive functioning in old age are inconsistent and inconclusive so far. Therefore, the present study set out to investigate the relation of the number of languages spoken to cognitive performance and its interplay with several other markers of cognitive reserve in a large sample of older adults. Two thousand eight hundred and twelve older adults served as sample for the present study. Psychometric tests on verbal abilities, basic processing speed, and cognitive flexibility were administered. In addition, individuals were interviewed on their different languages spoken on a regular basis, educational attainment, occupation, and engaging in different activities throughout adulthood. Higher number of languages regularly spoken was significantly associated with better performance in verbal abilities and processing speed, but unrelated to cognitive flexibility. Regression analyses showed that the number of languages spoken predicted cognitive performance over and above leisure activities/physical demand of job/gainful activity as respective additional predictor, but not over and above educational attainment/cognitive level of job as respective additional predictor. There was no significant moderation of the association of the number of languages spoken with cognitive performance in any model. Present data suggest that speaking different languages on a regular basis may additionally contribute to the build-up of cognitive reserve in old age. Yet, this may not be universal, but linked to verbal abilities and basic cognitive processing speed. Moreover, it may be dependent on other types of cognitive stimulation that individuals also engaged in during their life course.

  5. Impact of Article Page Count and Number of Authors on Citations in Disability Related Fields: A Systematic Review Article.

    Science.gov (United States)

    Ahmed, Abubakar; Adam, Mastura; Ghafar, Norafida A; Muhammad, Murtala; Ebrahim, Nader Ale

    2016-09-01

    Citation metrics and total publications in a field has become the gold standard for rating researchers and viability of a field. Hence, stimulating demand for citation has led to a search for useful strategies to improve performance metric index. Meanwhile, title, abstract and morphologic qualities of the articles attract researchers to scientific publications. Yet, there is relatively little understanding of the citation trend in disability related fields. We aimed to provide an insight into the factors associated with citation increase in this field. Additionally, we tried to know at what page number an article might appear attractive to disability researchers needs. Thus, our focus is placed on the article page count and the number of authors contributing to the fields per article. To this end, we evaluated the quantitative characteristics of top cited articles in the fields with a total citation (≥50) in the Web of Science (WoS) database. Using one-way independent ANOVA, data extracted spanning a period of 1980-2015 were analyzed, while the non-parametric data analysis uses Kruskal-Walis test. Articles with 11 to 20 pages attract more citations followed by those within the range of zero to 10. Articles with upward 21 pages are the least cited. Surprisingly, articles with more than two authors are significantly ( P <0.05) less cited and the citation decreases as the number of authors increased. Collaborative studies enjoy wider utilization and more citation, yet discounted merit of additional pages and limited collaborative research in disability field is revealed in this study.

  6. Chasing sympatric speciation: The relative importance and genetic basis of prezygotic isolation barriers in diverging populations of Spodoptera frugiperda

    NARCIS (Netherlands)

    Hänniger, S.

    2015-01-01

    This thesis investigates the mechanisms underlying three prezygotic isolation barriers between the corn- and the rice-strain of the noctuid moth Spodoptera frugiperda to determine possible interactions between these isolation barriers and their relative importance for sympatric speciation. First, we

  7. The relative importance of food biomass and quality for patch and habitat choice in Brent Geese Branta bernicla

    NARCIS (Netherlands)

    Bos, D; Drent, RH; Rubinigg, M; Stahl, J

    2005-01-01

    We studied the relative importance of food biomass and food quality for habitat preference in Brent Geese Branta bernicla by expefimentally manipulating forage parameters. Levels of biomass and ford quality (nitrogen content) were independently enhanced in plots of 2 x 6 m by temporary exclusion

  8. On the relative importance of vegetation terms in computational fluid dynamics on flow and Dispersion in the urban environment

    NARCIS (Netherlands)

    Gromke, C.B.; Blocken, B.J.E.

    2013-01-01

    The relative importance of vegetation terms was analysed for flow and dispersion in an urban street canyon with avenue-trees. To this end, simulations with three k-e turbulence models and different approaches to model vegetation were performed. The different approaches resulted in rather slight

  9. 78 FR 29392 - Embedded Digital Devices in Safety-Related Systems, Systems Important to Safety, and Items Relied...

    Science.gov (United States)

    2013-05-20

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0098] Embedded Digital Devices in Safety-Related Systems, Systems Important to Safety, and Items Relied on for Safety AGENCY: Nuclear Regulatory Commission. ACTION... (NRC) is issuing for public comment Draft Regulatory Issue Summary (RIS) 2013-XX, ``Embedded Digital...

  10. Relative importance of plant-mediated bottom-up and top-down forces on herbivore abundance on Brassica oleracea

    NARCIS (Netherlands)

    Kos, M.; Broekgaarden, C.; Kabouw, P.; Oude Lenferink, K.; Poelman, E.H.; Vet, L.E.M.; Dicke, M.; Loon, van J.J.A.

    2011-01-01

    1. Arthropod communities are structured by complex interactions between bottom-up (resource-based) and top-down (natural enemy-based) forces. Their relative importance in shaping arthropod communities, however, continues to be under debate. Bottom-up and top-down forces can be affected by

  11. The Fit between Students’ Lesson Perceptions and Desires: Relations with Student Characteristics and the Importance of Motivation

    NARCIS (Netherlands)

    Könings, Karen; Brand-Gruwel, Saskia; Van Merriënboer, Jeroen

    2011-01-01

    Könings, K. D., Brand-Gruwel, S., & Van Merriënboer, J. J. G. (2011). The match between students’ lesson perceptions and preferences: Relations with student characteristics and the importance of motivation. Educational Research, 53(4), 439-457.

  12. 31 CFR 560.505 - Importation of certain Iranian-origin services authorized; activities related to certain visa...

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Importation of certain Iranian-origin... Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN..., provided that the persons are not coming to the United States to work as an agent, employee or contractor...

  13. Child-rearing practices toward children with hemophilia: The relative importance of clinical characteristics and parental emotional reactions

    NARCIS (Netherlands)

    Banis, Hendrika; Suurmeijer, Th.P.B.M.; van Peer, D.R.

    This study addresses the relative importance of clinical characteristics of the child and parental emotional reactions, to child-rearing practices towards children who suffer from hemophilia. The variables were assessed in a Dutch sample of 108 zero-to-twelve-year-old boys with hemophilia and their

  14. Methodological Adaptations for Investigating the Perceptions of Language-Impaired Adolescents Regarding the Relative Importance of Selected Communication Skills

    Science.gov (United States)

    Reed, Vicki A.; Brammall, Helen

    2006-01-01

    This article describes the systematic and detailed processes undertaken to modify a research methodology for use with language-impaired adolescents. The original methodology had been used previously with normally achieving adolescents and speech pathologists to obtain their opinions about the relative importance of selected communication skills…

  15. A discussion of system reliability and the relative importance of pumps and valves to overall system availability

    Energy Technology Data Exchange (ETDEWEB)

    Poole, A.B. [Oak Ridge National Lab., TN (United States)

    1996-12-01

    An analysis was undertaken to establish preliminary trends for how component aging can effect failure rates for swing check valves, centrifugal pumps and motor operated valves. These failure rate trends were evaluated over time and linear aging rate models established. The failure rate models were then used with classic reliability theories to estimate reliability as a function of operating time. Reliability theory was also used to establish a simple system reliability model. Using the system model, the relative importance of pumps and valves to the overall system reliability were studied. Conclusions were established relative to overall system availability over time and the relative unavailabilities of the various components studied.

  16. A discussion of system reliability and the relative importance of pumps and valves to overall system availability

    International Nuclear Information System (INIS)

    Poole, A.B.

    1996-01-01

    An analysis was undertaken to establish preliminary trends for how component aging can effect failure rates for swing check valves, centrifugal pumps and motor operated valves. These failure rate trends were evaluated over time and linear aging rate models established. The failure rate models were then used with classic reliability theories to estimate reliability as a function of operating time. Reliability theory was also used to establish a simple system reliability model. Using the system model, the relative importance of pumps and valves to the overall system reliability were studied. Conclusions were established relative to overall system availability over time and the relative unavailabilities of the various components studied

  17. Decree from July 25, 2015 related to general prescriptions applicable to geothermal activities of minor importance. Decree from July 25, 2015 related to the certification of drilling companies intervening in geothermal energy of minor importance. Decree from July 25, 2015 related to the zoning map in the field minor importance geothermal energy

    International Nuclear Information System (INIS)

    Delduc, P.; Blanc, P.; Michel, L.

    2015-01-01

    These decrees concern various actors of the geothermal sector in the case of projects and works of minor importance. The first one defines general technical prescriptions applicable to a geothermal site of minor importance, the conditions related to the implantation of a geothermal installation of minor importance, measures to be implemented when performing geothermal works and when stopping its exploitation, control and maintenance modalities in order to prevent risks for the environment and to preserve water resource quality. The second decree defines measures to be implemented by drilling companies in the case of geothermal projects of minor importance. The third decree defines the map of geothermal areas of minor importance, specifies the map elaboration methodology and its reviewing modalities

  18. The development process and its relation to oil revenues and dependence on imported labor market in Saudi Arabia

    International Nuclear Information System (INIS)

    Almtairi, N.M.

    1991-01-01

    This study describes and analyzes the process of development in Saudi Arabia in relation to oil revenues and Saudi Arabian dependence on imported foreign labor. Modern development and societal change in Saudi Arabia began with the commercial exploitation of oil in 1939, therefore Saudi economy must be viewed from a dual perspective: a highly capital-intensive oil sector and a labor-intensive non-oil sector. In one generation the Kingdom created an infrastructure suitable to a rapid transformation from Bedouin tribes to a modern state, which became a leading regional power and now occupies an important place in international society. Important advances were made in social services, health services and education at all levels. Large-scale importation of foreign labor workers during the 1970s and early 1980s was necessary for the Development Plans. By the 1990s the major infrastructure was completed and only the maintenance work and minor projects remained for foreign labor sources

  19. A Theory of Evolving Natural Constants Based on the Unification of General Theory of Relativity and Dirac's Large Number Hypothesis

    International Nuclear Information System (INIS)

    Peng Huanwu

    2005-01-01

    Taking Dirac's large number hypothesis as true, we have shown [Commun. Theor. Phys. (Beijing, China) 42 (2004) 703] the inconsistency of applying Einstein's theory of general relativity with fixed gravitation constant G to cosmology, and a modified theory for varying G is found, which reduces to Einstein's theory outside the gravitating body for phenomena of short duration in small distances, thereby agrees with all the crucial tests formerly supporting Einstein's theory. The modified theory, when applied to the usual homogeneous cosmological model, gives rise to a variable cosmological tensor term determined by the derivatives of G, in place of the cosmological constant term usually introduced ad hoc. Without any free parameter the theoretical Hubble's relation obtained from the modified theory seems not in contradiction to observations, as Dr. Wang's preliminary analysis of the recent data indicates [Commun. Theor. Phys. (Beijing, China) 42 (2004) 703]. As a complement to Commun. Theor. Phys. (Beijing, China) 42 (2004) 703 we shall study in this paper the modification of electromagnetism due to Dirac's large number hypothesis in more detail to show that the approximation of geometric optics still leads to null geodesics for the path of light, and that the general relation between the luminosity distance and the proper geometric distance is still valid in our theory as in Einstein's theory, and give the equations for homogeneous cosmological model involving matter plus electromagnetic radiation. Finally we consider the impact of the modification to quantum mechanics and statistical mechanics, and arrive at a systematic theory of evolving natural constants including Planck's h-bar as well as Boltzmann's k B by finding out their cosmologically combined counterparts with factors of appropriate powers of G that may remain truly constant to cosmologically long time.

  20. Intra-uterine insemination: pregnancy rate in relation to number, size of pre-ovulatory follicles and day of insemination.

    Science.gov (United States)

    Karuppaswamy, J; Smedley, Mamin; Carter, Lindsay

    2009-03-01

    The objective of the study was to analyse the pregnancy rate in intra-uterine insemination (IUI) in relation to pre-ovulatory follicular number, size and day of insemination. A retrospective analysis of 216 completed IUI cycles was used in an attempt to identify significant variables predictive of treatment success. Couples with unexplained infertility and male factor infertility underwent IUI with or without ovarian stimulation. The mean number of IUI cycles per patient was 4.1, the overall pregnancy rate was 27.3% per patient, and the pregnancy rate per cycle was 6.9%. The pregnancy rate was 4.4% when one follicle was produced, whereas with more than two follicles, the rate increased to 21.2%. Hormonal stimulation using clomiphene citrate and/or human menopausal gonadotrophin/follicle stimulating hormone yielded a significant higher pregnancy rate compared to IUI in natural cycles (10.3% versus 3.3%). Although not statistically significant, the pregnancy rate decreased with advancing age of woman. The results suggest that IUI is a useful method of assisted conception in unexplained infertility and higher pregnancy rates can be achieved with good patient selection and ovarian stimulation.

  1. Emotional Reactions to Deviance in Groups: The Relation between Number of Angry Reactions, Felt Rejection, and Conformity

    Directory of Open Access Journals (Sweden)

    Marc W. Heerdink

    2015-06-01

    Full Text Available How many members of a group need to express their anger in order to influence a deviant group member's behavior? In two studies, we examine whether an increase in number of angry group members affects the extent to which a deviant individual feels rejected, and we investigate downstream effects on conformity. We show that each additional angry reaction linearly increases the extent to which a deviant individual feels rejected, and that this relation is independent of the total number of majority members (Study 1. This felt rejection is then shown to lead to anti-conformity unless two conditions are met: (1 the deviant is motivated to seek reacceptance in the group, and (2 conformity is instrumental in gaining reacceptance because it is observable by the majority (Study 2. These findings show that angry reactions are likely to trigger anti-conformity in a deviant, but they are also consistent with a motivational account of conformity, in which conformity is strategic behavior aimed at gaining reacceptance from the group.

  2. Emotional reactions to deviance in groups: the relation between number of angry reactions, felt rejection, and conformity.

    Science.gov (United States)

    Heerdink, Marc W; van Kleef, Gerben A; Homan, Astrid C; Fischer, Agneta H

    2015-01-01

    How many members of a group need to express their anger in order to influence a deviant group member's behavior? In two studies, we examine whether an increase in number of angry group members affects the extent to which a deviant individual feels rejected, and we investigate downstream effects on conformity. We show that each additional angry reaction linearly increases the extent to which a deviant individual feels rejected, and that this relation is independent of the total number of majority members (Study 1). This felt rejection is then shown to lead to anti-conformity unless two conditions are met: (1) the deviant is motivated to seek reacceptance in the group, and (2) conformity is instrumental in gaining reacceptance because it is observable by the majority (Study 2). These findings show that angry reactions are likely to trigger anti-conformity in a deviant, but they are also consistent with a motivational account of conformity, in which conformity is strategic behavior aimed at gaining reacceptance from the group.

  3. Moment of inertia, quadrupole moment, Love number of neutron star and their relations with strange-matter equations of state

    Science.gov (United States)

    Bandyopadhyay, Debades; Bhat, Sajad A.; Char, Prasanta; Chatterjee, Debarati

    2018-02-01

    We investigate the impact of strange-matter equations of state involving Λ hyperons, Bose-Einstein condensate of K- mesons and first-order hadron-quark phase transition on moment of inertia, quadrupole moment and tidal deformability parameter of slowly rotating neutron stars. All these equations of state are compatible with the 2 M_{solar} constraint. The main findings of this investigation are the universality of the I- Q and I -Love number relations, which are preserved by the EoSs including Λ hyperons and antikaon condensates, but broken in the presence of a first-order hadron-quark phase transition. Furthermore, it is also noted that the quadrupole moment approaches the Kerr value of a black hole for maximum-mass neutron stars.

  4. Importance of Women's Relative Socioeconomic Status within Sexual Relationships in Communication about Safer Sex and HIV/STI Prevention.

    Science.gov (United States)

    Muchomba, Felix M; Chan, Christine; El-Bassel, Nabila

    2015-06-01

    The socioeconomic status (SES) of women is increasingly considered an important factor for HIV/STI risk. The HIV/STI literature has largely focused on women's absolute levels of SES, and therefore, the importance of their SES relative to their male sexual partners remains understudied. This paper examines the association between women's relative SES and frequency of safer sex communication among heterosexual couples. A convenience sample of 342 couples (N = 684) recruited in New York City was asked about frequency of discussions with their partner about the need to use male condoms, about HIV prevention, and about STI prevention in the previous 90 days. Differences between partners in education, income, employment, housing, and incarceration history were combined using principal component analysis to form an index of women's relative SES. Negative binomial regression models assessed associations between woman's relative SES and communication frequency controlling for age, sex, race, ethnicity, education, and relationship type using a generalized estimating equation framework. On average, participants had 2.5, 4.2, and 4.8 discussions regarding the need to use male condoms, about HIV prevention, and about STI prevention, respectively. A one standard deviation increase in a woman's relative SES score was associated with increased frequency of discussions about male condom use (adjusted rate ratio [aRR], 1.15; 95% confidence interval [CI], 1.03-1.29), about HIV prevention (aRR, 1.25; CI, 1.14-1.37), and about STI prevention (aRR, 1.29; CI, 1.18-1.41). Women's relative SES may be an important factor for sexual communication, and further research on its role in HIV/STI risk may uncover avenues for intervention.

  5. Changing Mental Representations Using Related Physical Models: The Effects of Analyzing Number Lines on Learner Internal Scale of Numerical Magnitude

    Science.gov (United States)

    Bengtson, Barbara J.

    2013-01-01

    Understanding the linear relationship of numbers is essential for doing practical and abstract mathematics throughout education and everyday life. There is evidence that number line activities increase learners' number sense, improving the linearity of mental number line representations (Siegler & Ramani, 2009). Mental representations of…

  6. FIRE: an SPSS program for variable selection in multiple linear regression analysis via the relative importance of predictors.

    Science.gov (United States)

    Lorenzo-Seva, Urbano; Ferrando, Pere J

    2011-03-01

    We provide an SPSS program that implements currently recommended techniques and recent developments for selecting variables in multiple linear regression analysis via the relative importance of predictors. The approach consists of: (1) optimally splitting the data for cross-validation, (2) selecting the final set of predictors to be retained in the equation regression, and (3) assessing the behavior of the chosen model using standard indices and procedures. The SPSS syntax, a short manual, and data files related to this article are available as supplemental materials from brm.psychonomic-journals.org/content/supplemental.

  7. Alpha proteobacteria of genus Anaplasma (Rickettsiales: Anaplasmataceae): Epidemiology and characteristics of Anaplasma species related to veterinary and public health importance.

    Science.gov (United States)

    Atif, Farhan Ahmad

    2016-05-01

    The Anaplasma species are important globally distributed tick-transmitted bacteria of veterinary and public health importance. These pathogens, cause anaplasmosis in domestic and wild animal species including humans. Rhipicephalus, Ixodes, Dermacentor and Amblyomma genera of ticks are the important vectors of Anaplasma. Acute anaplasmosis is usually diagnosed upon blood smear examination followed by antibodies and nucleic acid detection. All age groups are susceptible but prevalence increases with age. Serological cross-reactivity is one of the important issues among Anaplasma species. They co-exist and concurrent infections occur in animals and ticks in same geographic area. These are closely related bacteria and share various common attributes which should be considered while developing vaccines and diagnostic assays. Movement of susceptible animals from non-endemic to endemic regions is the major risk factor of bovine/ovine anaplasmosis and tick-borne fever. Tetracyclines are currently available drugs for clearance of infection and treatment in humans and animals. Worldwide vaccine is not yet available. Identification, elimination of reservoirs, vector control (chemical and biological), endemic stability, habitat modification, rearing of tick resistant breeds, chemotherapy and tick vaccination are major control measures of animal anaplasmosis. Identification of reservoirs and minimizing the high-risk tick exposure activities are important control strategies for human granulocytic anaplasmosis.

  8. The effect of visual parameters on neural activation during nonsymbolic number comparison and its relation to math competency.

    Science.gov (United States)

    Wilkey, Eric D; Barone, Jordan C; Mazzocco, Michèle M M; Vogel, Stephan E; Price, Gavin R

    2017-10-01

    Nonsymbolic numerical comparison task performance (whereby a participant judges which of two groups of objects is numerically larger) is thought to index the efficiency of neural systems supporting numerical magnitude perception, and performance on such tasks has been related to individual differences in math competency. However, a growing body of research suggests task performance is heavily influenced by visual parameters of the stimuli (e.g. surface area and dot size of object sets) such that the correlation with math is driven by performance on trials in which number is incongruent with visual cues. Almost nothing is currently known about whether the neural correlates of nonsymbolic magnitude comparison are also affected by visual congruency. To investigate this issue, we used functional magnetic resonance imaging (fMRI) to analyze neural activity during a nonsymbolic comparison task as a function of visual congruency in a sample of typically developing high school students (n = 36). Further, we investigated the relation to math competency as measured by the preliminary scholastic aptitude test (PSAT) in 10th grade. Our results indicate that neural activity was modulated by the ratio of the dot sets being compared in brain regions previously shown to exhibit an effect of ratio (i.e. left anterior cingulate, left precentral gyrus, left intraparietal sulcus, and right superior parietal lobe) when calculated from the average of congruent and incongruent trials, as it is in most studies, and that the effect of ratio within those regions did not differ as a function of congruency condition. However, there were significant differences in other regions in overall task-related activation, as opposed to the neural ratio effect, when congruent and incongruent conditions were contrasted at the whole-brain level. Math competency negatively correlated with ratio-dependent neural response in the left insula across congruency conditions and showed distinct correlations when

  9. Investigation of nuclide importance to functional requirements related to transport and long-term storage of LWR spent fuel

    International Nuclear Information System (INIS)

    Broadhead, B.L.; DeHart, M.D.; Ryman, J.C.; Tang, J.S.; Parks, C.V.

    1995-06-01

    This study investigates the relative importances of the various actinide, fission-product, and light-element isotopes associated with LWR spent fuel with respect to five analysis areas: criticality safety (absorption fractions), shielding (dose rate fractions), curies (fractional curies levels), decay heat (fraction of total watts), and radiological toxicity (fraction of potential committed effective dose equivalent). These rankings are presented for up to six different burnup/enrichment scenarios and at decay times from 2 to 100,000 years. Ranking plots for each of these analysis areas are given in an Appendix for completeness, as well as summary tables in the main body of the report. Summary rankings are presented in terms of high (greater than 10% contribution to the total), medium (between 1% and 10% contribution), and low (less than 1% contribution) for both short- and long-term cooling. When compared with the expected measurement accuracies, these rankings show that most of the important isotopes can be characterized sufficiently for the purpose of radionuclide generation/depletion code validation in each of the analysis areas. Because the main focus of this work is on the relative importances of isotopes associated with L at sign spent fuel, some conclusions may not be applicable to similar areas such as high-level waste (HLW) and nonfuel-bearing components (NFBC)

  10. Effects of competition on great and blue tit reproduction: intensity and importance in relation to habitat quality.

    Science.gov (United States)

    Dhondt, André A

    2010-01-01

    1. In studies on the effect of competition in plant communities two terms are used to describe its effects: the absolute reduction in growth of an individual as a consequence of the presence of another one is called intensity, while the relative impact of competition on an individual as a proportion of the impact of the whole environment is called importance. One school of thought is that the role of competition remains constant across productivity gradients, while the other is that it decreases with increasing severity. J.B. Grace (1991. A clarification of the debate between grime and tilman. Functional Ecology, 5, 583-587.) suggested that the apparent contradiction might be solved if we acknowledge that the two schools are discussing different aspects of competition: the intensity of competition might remain constant while its importance declines with increasing severity. 2. There are no studies that compare intensity and importance of competition in bird populations between areas that differ in quality or productivity and hence it is not possible to make predictions how intensity or importance of competition would vary between them. 3. I compared variation in intensity and importance of competition of three demographic variables between five plots that differ strongly in quality for great Parus major L. and blue tit Cyanistes caeruleus (L.). 4. Both intensity and importance of competition are larger in great than in blue tit populations meaning that the effect of competition on demographic variables is stronger in great than in blue tits and that the contribution of competition to variation in these variables is relatively higher in great than in blue tits. 5. Intensity of competition is higher in low quality than in high quality plots for both species, a result not expected from studies in plant communities. 6. Importance of competition varies strongly between plots. It is larger in oak-dominated plots than in mixed deciduous plots. 7. In birds breeding density

  11. Yeast communities from host plants and associated Drosophila in southern arizona: new isolations and analysis of the relative importance of hosts and vectors on comunity composition.

    Science.gov (United States)

    Ganter, Philip F; Starmer, William T; Lachance, Marc-Andre; Phaff, Herman J

    1986-10-01

    The yeast communities from slime fluxes of three deciduous trees (Prosopis juliflora, Populus fremontii and Quercus emoryi) and the necroses of two cacti (Opuntia phaeacantha and Carnegiea gigantea) were surveyed in the region of Tucson, Arizona. In addition, the yeasts carried by dipterans associated with the fluxes or necroses (Drosophila carbonaria, D. brooksae, D. nigrospiracula, D. mettleri, and Aulacigaster leucopeza) were sampled. The results indicate that each host sampled had a distinct community of yeasts associated with it. The dipterans, which can act as vectors of the yeasts, deposited yeasts from other sources in addition to those found on their associated hosts. It is argued that host plant physiology is relatively more important than the activity of the vector in determining yeast community composition. Furthermore, the average number of yeast species per flux or necrosis is not different from the average number of yeast species per fly. It is hypothesized that the vector may affect the number of species per individual flux or not, and that the number is lower than the rot or necrosis could potentially support.

  12. Relative effects of disturbance on red imported fire ants and native ant species in a longleaf pine ecosystem

    DEFF Research Database (Denmark)

    Stuble, Katharine L.; Kirkman, L. Katherine; Carroll, C. Ronald

    2011-01-01

    and cases in which non-native species become established in intact (lacking extensive anthropogenic soil disturbance) communities and subsequently diminish the abundance and richness of native species is challenging on the basis of observation alone. The red imported fire ant (Solenopsis invicta......), an invasive species that occurs throughout much of the southeastern United States, is such an example. Rather than competitively displacing native species, fire ants may become established only in disturbed areas in which native species richness and abundance are already reduced. We used insecticide to reduce......, the abundance of native ants increased to levels comparable to those in control plots after 1 year. Our findings suggest that factors other than large reductions in ant abundance and species density (number of species per unit area) may affect the establishment of fire ants and that the response of native ants...

  13. Chocolate Numbers

    OpenAIRE

    Ji, Caleb; Khovanova, Tanya; Park, Robin; Song, Angela

    2015-01-01

    In this paper, we consider a game played on a rectangular $m \\times n$ gridded chocolate bar. Each move, a player breaks the bar along a grid line. Each move after that consists of taking any piece of chocolate and breaking it again along existing grid lines, until just $mn$ individual squares remain. This paper enumerates the number of ways to break an $m \\times n$ bar, which we call chocolate numbers, and introduces four new sequences related to these numbers. Using various techniques, we p...

  14. The number of sectors and other risk factors related to fatigue among shorthaul commercial pilots in Indonesia

    Directory of Open Access Journals (Sweden)

    Inne Yuliawati

    2016-03-01

     AbstractBackground: Fatigue could impair cognitive function in pilots which may lead to accidents in short-haul flight. Theaim of this study was to identify the risk factors related to fatigue among short-haul commercial pilots in Indonesia.Methods: A cross-sectional study with purposive sampling was conducted among Boeing 737 seriestyped-rating pilots taking medical examination at the Civil Aviation Medical Center, Jakarta from May5-26, 2014. Fatigue was measured with Self-Reporting Questionnaire, Fatigue Severity Scale (FSS. Datawere collected using anonymous self-reporting questionnaire on demographics, workload, sleep restriction(Epworth Sleepiness Scale-ESS, personal factors, and managerial support. Linear regression was used toidentify dominant risk factors related to fatigue.Results: During data collection, 785 pilots were taking medical examination, 382 pilots were willing toparticipate, and 239 pilots met the criteria. The FSS mean was 4.66 ± 1.202. The number of sectors in 24hours, flight times of unplanned flights in 30 days, and sleep restriction were dominant factors of fatigue.Each additional sector increased FSS by 0.371 points [regression coefficient (β = 0.371; P = 0.000].Furthermore, each additional ESS, increased FSS by 0.043 points (β = 0.043; P = 0.008, while eachadditional unplanned flights increased FSS by 0.033 points (β = 0.033; P = 0.000.Conclusions: Additional number of sectors in 24 hours, additional unplanned flight times within 30 days,and sleep restriction increased the risk of fatigue among short-haul commercial pilots in Indonesia. (HealthScience Journal of Indonesia 2015;6:69-75Keyword: Fatigue, number of sectors, pilots, Indonesia

  15. Criticality accident in uranium fuel processing plant. The estimation of the total number of fissions with related reactor physics parameters

    International Nuclear Information System (INIS)

    Nishina, Kojiro; Oyamatsu, Kazuhiro; Kondo, Shunsuke; Sekimoto, Hiroshi; Ishitani, Kazuki; Yamane, Yoshihiro; Miyoshi, Yoshinori

    2000-01-01

    This accident occurred when workers were pouring a uranium solution into a precipitation tank with handy operation against the established procedure and both the cylindrical diameter and the total mass exceeded the limited values. As a result, nuclear fission chain reactor in the solution reached not only a 'criticality' state continuing it independently but also an instantly forming criticality state exceed the criticality and increasing further nuclear fission number. The place occurring the accident at this time was not reactor but a place having not to form 'criticality' called by a processing process of uranium fuel. In such place, as because of relating to mechanism of chain reaction, it is required naturally for knowledge on the reactor physics, it is also necessary to understand chemical reaction in chemical process, and functions of tanks, valves and pumps mounted at the processes. For this purpose, some information on uranium concentration ratio, atomic density of nuclides largely affecting to chain reaction such as uranium, hydrogen, and so forth in the solution, shape, inner structure and size of container for the solution, and its temperature and total volume, were necessary for determining criticality volume of the accident uranium solution by using nuclear physics procedures. Here were described on estimation of energy emission in the JCO accident, estimation from analytical results on neutron and solution, calculation of various nuclear physics property estimation on the JCO precipitation tank at JAERI. (G.K.)

  16. Relative importance of precipitation frequency and intensity in inter-annual variation of precipitation in Singapore during 1980-2013

    Science.gov (United States)

    Li, Xin; Babovic, Vladan

    2017-04-01

    Observed studies on inter-annual variation of precipitation provide insight into the response of precipitation to anthropogenic climate change and natural climate variability. Inter-annual variation of precipitation results from the concurrent variations of precipitation frequency and intensity, understanding of the relative importance of frequency and intensity in the variability of precipitation can help fathom its changing properties. Investigation of the long-term changes of precipitation schemes has been extensively carried out in many regions across the world, however, detailed studies of the relative importance of precipitation frequency and intensity in inter-annual variation of precipitation are still limited, especially in the tropics. Therefore, this study presents a comprehensive framework to investigate the inter-annual variation of precipitation and the dominance of precipitation frequency and intensity in a tropical urban city-state, Singapore, based on long-term (1980-2013) daily precipitation series from 22 rain gauges. First, an iterative Mann-Kendall trend test method is applied to detect long-term trends in precipitation total, frequency and intensity at both annual and seasonal time scales. Then, the relative importance of precipitation frequency and intensity in inducing the inter-annual variation of wet-day precipitation total is analyzed using a dominance analysis method based on linear regression. The results show statistically significant upward trends in wet-day precipitation total, frequency and intensity at annual time scale, however, these trends are not evident during the monsoon seasons. The inter-annual variation of wet-day precipitation is mainly dominated by precipitation intensity for most of the stations at annual time scale and during the Northeast monsoon season. However, during the Southwest monsoon season, the inter-annual variation of wet-day precipitation is mainly dominated by precipitation frequency. These results have

  17. Phytophthora megakarya and Phytophthora palmivora, Closely Related Causal Agents of Cacao Black Pod Rot, Underwent Increases in Genome Sizes and Gene Numbers by Different Mechanisms

    Science.gov (United States)

    Ali, Shahin S.; Shao, Jonathan; Lary, David J.; Kronmiller, Brent A.; Shen, Danyu; Strem, Mary D.; Amoako-Attah, Ishmael; Akrofi, Andrew Yaw; Begoude, B.A. Didier; ten Hoopen, G. Martijn; Coulibaly, Klotioloma; Kebe, Boubacar Ismaël; Melnick, Rachel L.; Guiltinan, Mark J.; Tyler, Brett M.; Meinhardt, Lyndel W.

    2017-01-01

    Phytophthora megakarya (Pmeg) and Phytophthora palmivora (Ppal) are closely related species causing cacao black pod rot. Although Ppal is a cosmopolitan pathogen, cacao is the only known host of economic importance for Pmeg. Pmeg is more virulent on cacao than Ppal. We sequenced and compared the Pmeg and Ppal genomes and identified virulence-related putative gene models (PGeneM) that may be responsible for their differences in host specificities and virulence. Pmeg and Ppal have estimated genome sizes of 126.88 and 151.23 Mb and PGeneM numbers of 42,036 and 44,327, respectively. The evolutionary histories of Pmeg and Ppal appear quite different. Postspeciation, Ppal underwent whole-genome duplication whereas Pmeg has undergone selective increases in PGeneM numbers, likely through accelerated transposable element-driven duplications. Many PGeneMs in both species failed to match transcripts and may represent pseudogenes or cryptic genetic reservoirs. Pmeg appears to have amplified specific gene families, some of which are virulence-related. Analysis of mycelium, zoospore, and in planta transcriptome expression profiles using neural network self-organizing map analysis generated 24 multivariate and nonlinear self-organizing map classes. Many members of the RxLR, necrosis-inducing phytophthora protein, and pectinase genes families were specifically induced in planta. Pmeg displays a diverse virulence-related gene complement similar in size to and potentially of greater diversity than Ppal but it remains likely that the specific functions of the genes determine each species’ unique characteristics as pathogens. PMID:28186564

  18. Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

    Directory of Open Access Journals (Sweden)

    Christiaan Klijn

    2010-01-01

    Full Text Available Tumorigenesis is a multi-step process in which normal cells transform into malignant tumors following the accumulation of genetic mutations that enable them to evade the growth control checkpoints that would normally suppress their growth or result in apoptosis. It is therefore important to identify those combinations of mutations that collaborate in cancer development and progression. DNA copy number alterations (CNAs are one of the ways in which cancer genes are deregulated in tumor cells. We hypothesized that synergistic interactions between cancer genes might be identified by looking for regions of co-occurring gain and/or loss. To this end we developed a scoring framework to separate truly co-occurring aberrations from passenger mutations and dominant single signals present in the data. The resulting regions of high co-occurrence can be investigated for between-region functional interactions. Analysis of high-resolution DNA copy number data from a panel of 95 hematological tumor cell lines correctly identified co-occurring recombinations at the T-cell receptor and immunoglobulin loci in T- and B-cell malignancies, respectively, showing that we can recover truly co-occurring genomic alterations. In addition, our analysis revealed networks of co-occurring genomic losses and gains that are enriched for cancer genes. These networks are also highly enriched for functional relationships between genes. We further examine sub-networks of these networks, core networks, which contain many known cancer genes. The core network for co-occurring DNA losses we find seems to be independent of the canonical cancer genes within the network. Our findings suggest that large-scale, low-intensity copy number alterations may be an important feature of cancer development or maintenance by affecting gene dosage of a large interconnected network of functionally related genes.

  19. Childhood Maltreatment and the Development of Relational and Physical Aggression: The Importance of a Gender-Informed Approach

    Science.gov (United States)

    Cullerton-Sen, Crystal; Cassidy, Adam R.; Murray-Close, Dianna; Cicchetti, Dante; Crick, Nicki R.; Rogosch, Fred A.

    2012-01-01

    This investigation examined the associations between maltreatment and aggression using a gender-informed approach. Peer ratings, peer nominations, and counselor reports of aggression were collected on 211 maltreated and 199 non-maltreated inner-city youth (mean age = 9.9 years) during a summer day camp. Maltreatment was associated with aggressive conduct; however, these effects were qualified by gender, maltreatment subtype, and the form of aggression under investigation. Findings revealed that maltreatment was associated with physical aggression for boys and relational aggression for girls. Physical abuse was associated with physically aggressive behaviors, but sexual abuse predicted relational aggression for girls only. Findings suggest that investigating the interaction between familial risk and gender is important in understanding aggressive behaviors of boys and girls. PMID:19037946

  20. CME Dynamics Using STEREO and LASCO Observations: The Relative Importance of Lorentz Forces and Solar Wind Drag

    Science.gov (United States)

    Sachdeva, Nishtha; Subramanian, Prasad; Vourlidas, Angelos; Bothmer, Volker

    2017-09-01

    We seek to quantify the relative contributions of Lorentz forces and aerodynamic drag on the propagation of solar coronal mass ejections (CMEs). We use Graduated Cylindrical Shell (GCS) model fits to a representative set of 38 CMEs observed with the Solar and Heliospheric Observatory (SOHO) and the Solar and Terrestrial Relations Observatory (STEREO) spacecraft. We find that the Lorentz forces generally peak between 1.65 and 2.45 R⊙ for all CMEs. For fast CMEs, Lorentz forces become negligible in comparison to aerodynamic drag as early as 3.5 - 4 R⊙. For slow CMEs, however, they become negligible only by 12 - 50 R⊙. For these slow events, our results suggest that some of the magnetic flux might be expended in CME expansion or heating. In other words, not all of it contributes to the propagation. Our results are expected to be important in building a physical model for understanding the Sun-Earth dynamics of CMEs.

  1. Comparison of x ray computed tomography number to proton relative linear stopping power conversion functions using a standard phantom.

    Science.gov (United States)

    Moyers, M F

    2014-06-01

    Adequate evaluation of the results from multi-institutional trials involving light ion beam treatments requires consideration of the planning margins applied to both targets and organs at risk. A major uncertainty that affects the size of these margins is the conversion of x ray computed tomography numbers (XCTNs) to relative linear stopping powers (RLSPs). Various facilities engaged in multi-institutional clinical trials involving proton beams have been applying significantly different margins in their patient planning. This study was performed to determine the variance in the conversion functions used at proton facilities in the U.S.A. wishing to participate in National Cancer Institute sponsored clinical trials. A simplified method of determining the conversion function was developed using a standard phantom containing only water and aluminum. The new method was based on the premise that all scanners have their XCTNs for air and water calibrated daily to constant values but that the XCTNs for high density/high atomic number materials are variable with different scanning conditions. The standard phantom was taken to 10 different proton facilities and scanned with the local protocols resulting in 14 derived conversion functions which were compared to the conversion functions used at the local facilities. For tissues within ±300 XCTN of water, all facility functions produced converted RLSP values within ±6% of the values produced by the standard function and within 8% of the values from any other facility's function. For XCTNs corresponding to lung tissue, converted RLSP values differed by as great as ±8% from the standard and up to 16% from the values of other facilities. For XCTNs corresponding to low-density immobilization foam, the maximum to minimum values differed by as much as 40%. The new method greatly simplifies determination of the conversion function, reduces ambiguity, and in the future could promote standardization between facilities. Although it

  2. Environmental radiological surveillance in perspective: the relative importance of environmental media as a function of effluent pathway and radionuclides

    International Nuclear Information System (INIS)

    Denham, D.H.

    1977-10-01

    Most published guidelines for environmental surveillance emphasize the collection and analysis of specific media (e.g. air, water, milk, direct radiation) without total regard for the potential dose impact of the radionuclides expected in or actually present in the effluent streams from nuclear facilities. To determine the relative importance of medium/nuclide combinations in environmental surveillance, the experience at major ERDA sites and at operating nuclear power plants was reviewed. Typical release rates for nuclide groupings (tritium, noble gases, radioiodine, mixed fission or activation products, and transuranics) in those effluent streams were followed through various environmental pathways. By using this scheme the environmental medium which is most prominent in the critical dose pathway to man was determined. It was also possible to determine points of short-or long-term contaminant accumulation. Following these calculations, each medium was ranked for a given nuclide/effluent pathway combination providing the relative importance of sampling specific environmental media with emphasis on the radiation dose to a critical population group. Finally, the results of these environmental pathway studies are presented in tabular form to provide ready reference for environmental surveillance program design or evaluation

  3. Disentangling the relative importance of changes in climate and land-use intensity in driving recent bird population trends.

    Directory of Open Access Journals (Sweden)

    Sarah M Eglington

    Full Text Available Threats to biodiversity resulting from habitat destruction and deterioration have been documented for many species, whilst climate change is regarded as increasingly impacting upon species' distribution and abundance. However, few studies have disentangled the relative importance of these two drivers in causing recent population declines. We quantify the relative importance of both processes by modelling annual variation in population growth of 18 farmland bird species in the UK as a function of measures of land-use intensity and weather. Modelled together, both had similar explanatory power in accounting for annual fluctuations in population growth. When these models were used to retrodict population trends for each species as a function of annual variation in land-use intensity and weather combined, and separately, retrodictions incorporating land-use intensity were more closely linked to observed population trends than retrodictions based only on weather, and closely matched the UK farmland bird index from 1970 onwards. Despite more stable land-use intensity in recent years, climate change (inferred from weather trends has not overtaken land-use intensity as the dominant driver of bird populations.

  4. Environmental radiological surveillance in perspective: the relative importance of environmental media as a function of effluent pathway and radionuclides

    International Nuclear Information System (INIS)

    Denham, D.H.

    1977-01-01

    Most published guidelines for environmental surveillance emphasize the collection and analysis of specific media (e.g. air, water, milk, direct radiation) without total regard for the potential dose impact of the radionuclides expected in or actually present in the effluent streams FR-om nuclear facilities. To determine the relative importance of medium/nuclide combinations in environmental surveillance, the experience at major ERDA sites and at operating nuclear power plants was reviewed. Typical release rates for nuclide groupings (tritium, noble gases, radioiodine, mixed fission or activation products, and transuranics) in those effluent streams were followed through various environmental pathways. By using this scheme the environmental medium which is most prominent in the critical dose pathway to man was determined. It was also possible to determine points of short-or long-term contaminant accumulation. Following these combination providing the relative importance of sampling specific environmental media with emphasis on the radiation dose to a critical population group. Finally, the results of these environmental pathway studies are presented in tabular form to provide ready reference for environmental surveillance program design or evaluation

  5. The relative importance among anthropogenic forcings of land use/land cover change in affecting temperature extremes

    Science.gov (United States)

    Chen, Liang; Dirmeyer, Paul A.

    2018-05-01

    Land use/land cover change (LULCC) exerts significant influence on regional climate extremes, but its relative importance compared with other anthropogenic climate forcings has not been thoroughly investigated. This study compares land use forcing with other forcing agents in explaining the simulated historical temperature extreme changes since preindustrial times in the CESM-Last Millennium Ensemble (LME) project. CESM-LME suggests that the land use forcing has caused an overall cooling in both warm and cold extremes, and has significantly decreased diurnal temperature range (DTR). Due to the competing effects of the GHG and aerosol forcings, the spatial pattern of changes in 1850-2005 climatology of temperature extremes in CESM-LME can be largely explained by the land use forcing, especially for hot extremes and DTR. The dominance of land use forcing is particularly evident over Europe, eastern China, and the central and eastern US. Temporally, the land-use cooling is relatively stable throughout the historical period, while the warming of temperature extremes is mainly influenced by the enhanced GHG forcing, which has gradually dampened the local dominance of the land use effects. Results from the suite of CMIP5 experiments partially agree with the local dominance of the land use forcing in CESM-LME, but inter-model discrepancies exist in the distribution and sign of the LULCC-induced temperature changes. Our results underline the overall importance of LULCC in historical temperature extreme changes, implying land use forcing should be highlighted in future climate projections.

  6. Genotypes analysis of ten genes related to eating quality of 22 Shanghai important rice varieties by molecular marker

    Directory of Open Access Journals (Sweden)

    XIE Mixue

    2013-08-01

    Full Text Available The improvement of rice eating quality is a very important direction of rice breeding.Clearing the different genotype of rice eating quality provides the basis for the parent selection on breeding good eating quality rice.Using molecular marker detection technology,genotypes of ten genes related to eating quality of 22 Shanghai important rice varieties,including conventional rice and hybrid parents were detected.The results showed that "Zixiangnuo 861" rice contained many poor genotypes which might affect rice eating quality.The genotypes of 3 male parents,"Xiangqin","R44" and "Fan14" for three kinds of hybrid rice,"Hannyouxiangqing","Qiuyoujinfeng" and "Huayou14",respectively,were not as good as their corresponding female parents,"HanfengA","JinfengA" and "Shen9A" and another conventional rice varieties.Wx polymorphism analysis showed that there were two glutinous rice,four soft rice japonica and 16 non-soft rice japonica."Baonong34","Jinfeng" and "Yinxiang18" had relatively better genotypes of the genes controlling eating quality among the 16 non-soft rice japonica.

  7. Environment and geographic distance differ in relative importance for determining fungal community of rhizosphere and bulk soil.

    Science.gov (United States)

    Zhang, Kaoping; Adams, Jonathan M; Shi, Yu; Yang, Teng; Sun, Ruibo; He, Dan; Ni, Yingying; Chu, Haiyan

    2017-09-01

    Rhizospheric fungi play major roles in both natural and agricultural ecosystems. However, little is known about the determinants of their diversity and biogeographic patterns. Here, we compared fungal communities in rhizosphere and bulk soils of wheat fields in the North China Plain. The rhizosphere had a lower fungal diversity (observed OTUs and Chao1) than bulk soil, and a distinct fungal community structure in rhizosphere compared with bulk soil. The relative importance of environmental factors and geographic distance for fungal distribution differed between rhizosphere and bulk soil. Environmental factors were the primary cause of variations in total fungal community and major fungal phyla in bulk soil. By contrast, fungal communities in soils loosely attached to roots were predictable from both environmental factors and influences of geographic distance. Communities in soils tightly attached to roots were mainly determined by geographic distance. Our results suggest that both contemporary environment processes (present-day abiotic and biotic environment characters) and historical processes (spatial isolation, dispersal limitation occurred in the past) dominate variations of fungal communities in wheat fields, but their relative importance of all these processes depends on the proximity of fungal community to the plant roots. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

  8. Quantifying The Relative Importance Of Phylogeny And Environmental Preferences As Drivers Of Gene Content In Prokaryotic Microorganisms

    Directory of Open Access Journals (Sweden)

    Javier eTamames

    2016-03-01

    Full Text Available Two complementary forces shape microbial genomes: vertical inheritance of genes by phylogenetic descent, and acquisition of new genes related to adaptation to particular habitats and lifestyles. Quantification of the relative importance of each driving force proved difficult. We determined the contribution of each factor, and identified particular genes or biochemical/cellular processes linked to environmental preferences (i.e., propensity of a taxon to live in particular habitats. Three types of data were confronted: [i] complete genomes, which provide gene content of different taxa; [ii] phylogenetic information, via alignment of 16S rRNA sequences, which allowed determination of the distance between taxa, and [iii] distribution of species in environments via 16S rRNA sampling experiments, reflecting environmental preferences of different taxa. The combination of these three datasets made it possible to describe and quantify the relationships among them. We found that, although phylogenetic descent was responsible for shaping most genomes, a discernible part of the latter was correlated to environmental adaptations. Particular families of genes were identified as environmental markers, as supported by direct studies such as metagenomic sequencing. These genes are likely important for adaptation of bacteria to particular conditions or habitats, such as carbohydrate or glycan metabolism genes being linked to host-associated environments.

  9. Relative Importance of Human Resource Practices on Affective Commitment and Turnover Intention in South Korea and United States

    Directory of Open Access Journals (Sweden)

    Jaeyoon Lee

    2018-05-01

    Full Text Available The main purpose of this study was to investigate the impact of perceived HR practices on affective commitment and turnover intention. This study explored which HR practices were relatively more important in predicting affective commitment and turnover intention. A total of 302 employees from the United States and 317 from South Korea completed the same questionnaires for assessing the aforementioned relationships. The results illustrated that among perceived HR practices, internal mobility had the most significant association with turnover intention in both the United States and South Korea. While internal mobility was a stronger predictor of affective commitment for the United States sample, training was the most important variable for predicting affective commitment in South Korea. The second purpose of the study was to examine whether individuals’ positive affect influences the relationship between perceived HR practices and affective commitment and turnover intention. In the United States, positive affect moderated the relationship between perceived HR practices and affective commitment and turnover intention such that the relationships were stronger for individuals reporting high positive affect relative to those reporting low positive affect. However, these relationships were not significant in South Korea. We discuss the implications of these results, study limitations, and practical suggestions for future research.

  10. Oral hygiene and number of oral mucosal lesion correlate with oral health-related quality of life in elderly communities

    Directory of Open Access Journals (Sweden)

    Dewi Agustina

    2014-03-01

    Full Text Available Background: Quality of life assessment mostly is based on general health. Deterioration of physiologic condition, polypharmacy and the high occurrence of chronic disease in elderly may manifest in oral cavity that can affect oral function, in turn it will affect quality of life of elderly. Purpose: This study was aimed to determine the correlation of oral health status and oral health-related quality of life (OHRQoL in elderly communities of Yogyakarta city. Method: Seventy three elders were subjects of this study. Data of OHRQoL and oral health status were obtained from modification of questionnaire of Dental Impact of Daily Living (DIDL Index and from intraoral examination, respectively. Intraoral examination comprised oral mucosal lesion amount, oral hygiene, DMFT index and periodontal tissue status. The data then were analyzed statistically using Pearson Product Moment Correlation. Result: The results showed that mean of DMFT index was 16.9 and 63% of subjects were found with gingivitis, most subject had moderate oral hygiene and each subject at least had two oral mucosal lesions. Mean score of quality of life was 27.2 and classified as satisfying. Oral hygiene and number of oral mucosal lesion had correlation with OHRQoL with r were -0.236 (Sig. : 0.045 and -0.288 (Sig. : 0.013, respectively. Conclusion: The study suggested that oral hygiene and number of oral mucosal lesion correlate with oral health related-quality of life in elderly communities of Yogyakarta city.Latar belakang: Penilaian kualitas hidup terutama didasarkan pada kesehatan umum. Memburuknya kondisi fisiologis, polifarmasi dan tingginya kejadian penyakit kronis pada lansia dapat termanifestasi di dalam rongga mulut sehingga dapat mempengaruhi fungsi mulut yang pada gilirannya akan mempengaruhi kualitas hidup lansia. Tujuan: Penelitian ini bertujuan untuk meneliti hubungan antara status kesehatan mulut dan kualitas hidup berdasarkan kesehatan mulut pada masyarakat lanjut

  11. Relative Importance Assigned to Health Care Rationing Principles at the Bedside: Evidence From a Portuguese and Bulgarian Survey.

    Science.gov (United States)

    Pinho, Micaela Moreira; Pinto Borges, Ana

    Activity was undertaken to develop a Prioritization Scoring Index for Portugal and Bulgaria that weights the importance given to ethical rationing principles that should guide decisions at the bedside. Data from two random samples of 355 Portuguese and 298 Bulgarian members of the public were collected from an online questionnaire. Questions asked about the level of importance given to specific issues related to patient's prioritization criteria. Responses were analyzed quantitatively with the SPSS. In the process of selecting the patient to treat, Portuguese and Bulgarian respondents seem unanimous in giving greater importance to (i) the treatment outcomes, (ii) the severity of illness, (iii) children, and (iv) patients' fragility. In general, Portuguese and Bulgarian respondents allocate more than 50% of the prioritization weight to equity considerations, approximately 35% to efficiency considerations, and 5% to lottery selection. Even so, Bulgarian respondents rate highly the equity and less the efficiency consideration than Portuguese respondents. Although the pursuit of efficiency seems to be valued by respondents, their major concern seems to be with the reduction of inequalities in health.

  12. Relative importance of social factors, conspecific density, and forest structure on space use by the endangered Red-cockaded Woodpecker: A new consideration for habitat restoration

    Energy Technology Data Exchange (ETDEWEB)

    Garabedian, James E. [Fisheries, Wildlife, and Conservation Biology Program, North Carolina State University, Raleigh, North Carolina, USA; Moorman, Christopher E. [Fisheries, Wildlife, and Conservation Biology Program, North Carolina State University, Raleigh, North Carolina, USA; Peterson, M. Nils [Fisheries, Wildlife, and Conservation Biology Program, North Carolina State University, Raleigh, North Carolina, USA; Kilgo, John C. [Southern Research Station, USDA Forest Service, Savannah River, New Ellenton, South Carolina, USA

    2018-03-14

    Understanding how the interplay between social behaviors and habitat structure influences space use is important for conservation of birds in restored habitat. We integrated fine-grained LiDAR-derived habitat data, spatial distribution of cavity trees, and spatially explicit behavioral observations in a multi-scale model to determine the relative importance of conspecific density, intraspecific interactions, and the distribution of cavities on space use by Red-cockaded Woodpeckers (Picoides borealis) on 2 sites in South Carolina, USA. We evaluated candidate models using information theoretic methods. Top scale-specific models included effects of conspecific density and number of cavity tree starts within 200 m of Red-cockaded Woodpecker foraging locations, and effects of the number of intraspecific interactions within 400 m of Red-cockaded Woodpecker foraging locations. The top multi-scale model for 22 of 34 Red-cockaded Woodpecker groups included covariates for the number of groups within 200 m of foraging locations and LiDARderived habitat with moderate densities of large pines (Pinus spp.) and minimal hardwood overstory. These results indicate distribution of neighboring groups was the most important predictor of space use once a minimal set of structural habitat thresholds was reached, and that placing recruitment clusters as little as 400 m from foraging partitions of neighboring groups may promote establishment of new breeding groups in unoccupied habitat. The presence of neighboring groups likely provides cues to foraging Red-cockaded Woodpeckers that facilitate prospecting prior to juvenile dispersal and, to a lesser extent, indicates high-quality forage resources. Careful consideration of local distribution of neighboring groups in potential habitat may improve managers’ ability to increase Red-cockaded Woodpecker density on restored landscapes and mitigate isolation of Red-cockaded Woodpecker groups, a problem that negatively affects fitness across the

  13. The number of injected same-day preschool vaccines relates to preadolescent needle fear and HPV uptake.

    Science.gov (United States)

    Baxter, Amy L; Cohen, Lindsey L; Burton, Mark; Mohammed, Anaam; Lawson, M Louise

    2017-07-24

    Fear of needles develops at approximately five years of age, and decreases compliance with healthcare. We sought to examine the relationship of preschool vaccine history, parent and preadolescent needle fear, and subsequent compliance with optional vaccines. As part of a private practice randomized controlled trial, parents and 10-12year olds rated needle anxiety on a 100mm visual analog scale. This follow-up cohort study compared their needle anxiety to previous vaccination records, including number of vaccinations between ages four and six years (total and same-day maximum), and subsequent initiation of the HPV vaccine through age 13. Of the 120 preadolescents enrolled between 4.28.09 and 1.19.2010, 117 received preschool vaccinations between ages four and six years. The likelihood of being in the upper quartile of fear (VAS≥83) five years later increased with each additional same-day injection (OR=3.108, p=0.0100 95%CI=1.311, 7.367), but was not related to total lifetime or total four-to-six year injections. Only 12.5% (15) of parents reported anxiety about their preadolescents' vaccines (VAS>50). Parent and child anxiety was weakly correlated (r=0.15). Eight children in the upper fear quartile began their HPV series (26.67%) compared to 14 in the lower quartile (48.28% VASfear needles five years later. Preadolescent needle fear was a stronger predictor than parent vaccine anxiety of subsequent HPV vaccine uptake. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. The Relative Importance of Spatial and Local Environmental Factors in Determining Beetle Assemblages in the Inner Mongolia Grassland.

    Directory of Open Access Journals (Sweden)

    Xiao-Dong Yu

    Full Text Available The aim of this paper is to increase understanding of the relative importance of the input of geographic and local environmental factors on richness and composition of epigaeic steppe beetles (Coleoptera: Carabidae and Tenebrionidae along a geographic (longitudinal/precipitation gradient in the Inner Mongolia grassland. Specifically, we evaluate the associations of environmental variables representing climate and environmental heterogeneity with beetle assemblages. Beetles were sampled using pitfall traps at 25 sites scattered across the full geographic extent of the study biome in 2011-2012. We used variance partitioning techniques and multi-model selection based on the Akaike information criterion to assess the relative importance of the spatial and environmental variables on beetle assemblages. Species richness and abundance showed unimodal patterns along the geographic gradient. Together with space, climate variables associated with precipitation, water-energy balance and harshness of climate had strong explanatory power in richness pattern. Abundance pattern showed strongest association with variation in temperature and environmental heterogeneity. Climatic factors associated with temperature and precipitation variables and the interaction between climate with space were able to explain a substantial amount of variation in community structure. In addition, the turnover of species increased significantly as geographic distances increased. We confirmed that spatial and local environmental factors worked together to shape epigaeic beetle communities along the geographic gradient in the Inner Mongolia grassland. Moreover, the climate features, especially precipitation, water-energy balance and temperature, and the interaction between climate with space and environmental heterogeneity appeared to play important roles on controlling richness and abundance, and species compositions of epigaeic beetles.

  15. The relative importance of climate and vegetation properties on patterns of North American breeding bird species richness

    International Nuclear Information System (INIS)

    Goetz, Scott J; Sun, Mindy; Zolkos, Scott; Hansen, Andy; Dubayah, Ralph

    2014-01-01

    Recent advances in remote sensing and ecological modeling warrant a timely and robust investigation of the ecological variables that underlie large-scale patterns of breeding bird species richness, particularly in the context of intensifying land use and climate change. Our objective was to address this need using an array of bioclimatic and remotely sensed data sets representing vegetation properties and structure, and other aspects of the physical environment. We first build models of bird species richness across breeding bird survey (BBS) routes, and then spatially predict richness across the coterminous US at moderately high spatial resolution (1 km). Predictor variables were derived from various sources and maps of species richness were generated for four groups (guilds) of birds with different breeding habitat affiliation (forest, grassland, open woodland, scrub/shrub), as well as all guilds combined. Predictions of forest bird distributions were strong (R 2 = 0.85), followed by grassland (0.76), scrub/shrub (0.63) and open woodland (0.60) species. Vegetation properties were generally the strongest determinants of species richness, whereas bioclimatic and lidar-derived vertical structure metrics were of variable importance and dependent upon the guild type. Environmental variables (climate and the physical environment) were also frequently selected predictors, but canopy structure variables were not as important as expected based on more local to regional scale studies. Relatively sparse sampling of canopy structure metrics from the satellite lidar sensor may have reduced their importance relative to other predictor variables across the study domain. We discuss these results in the context of the ecological drivers of species richness patterns, the spatial scale of bird diversity analyses, and the potential of next generation space-borne lidar systems relevant to vegetation and ecosystem studies. This study strengthens current understanding of bird species

  16. Investigating Kindergarteners' Number Sense and Self-Regulation Scores in Relation to Their Mathematics and Turkish Scores in Middle School

    Science.gov (United States)

    Ivrendi, Asiye

    2016-01-01

    Number sense and self-regulation are considered foundational skills for later school learning. This study aimed to investigate the predictive power of kindergarten children's number sense and self-regulation scores on their mathematics and Turkish language examination scores in the 5th and 6th grades. The participants in this study were 5th grade…

  17. Perfluoroalkyl acids and their precursors in Swedish food: The relative importance of direct and indirect dietary exposure

    International Nuclear Information System (INIS)

    Gebbink, Wouter A.; Glynn, Anders; Darnerud, Per Ola; Berger, Urs

    2015-01-01

    We analyzed food market basket samples obtained in Sweden from 1999, 2005, and 2010 for perfluoroalkyl acids (PFAAs) and a range of precursor compounds. Perfluorooctane sulfonic acid (PFOS) precursors were detected in all food year pools with the highest concentrations in 1999. Six polyfluoroalkyl phosphate diesters (diPAPs, 4:2/6:2, 6:2/6:2, 6:2/8:2, 8:2/8:2, 6:2/10:2, and 10:2/10:2) were detected in the year pools with the highest ∑diPAP concentrations in 1999 and 2005. All precursors were predominantly found in meat, fish, and/or eggs based on analysis of individual food groups from 1999. Based on year pools, PFOS precursors contributed between 4 and 1% as an indirect source to total dietary PFOS intakes between 1999 and 2010. Perfluorohexanoic acid (PFHxA) exposure originated entirely from diPAPs, whereas for perfluorooctanoic acid (PFOA) and perfluorodecanoic acid (PFDA), diPAPs contributed between 1 and 19% to total exposure. The lowest precursor contributions were generally seen in food samples from 2010. - Highlights: • Three PFOS precursors and six diPAPs were detected in food pools. • Precursor concentrations were highest in 1999 and 2005 food pools, and lowest in 2010. • The relative importance of precursors to total PFOS dietary intake was <4%. • The relative importance of diPAPs as an indirect dietary source of PFCAs was chain length dependent. - The relative contribution of precursors to PFOS dietary intakes is small, whereas the contribution of diPAPs to PFCA dietary intakes varies with the PFCA chain length

  18. Trajectories of childhood weight gain: the relative importance of local environment versus individual social and early life factors.

    Directory of Open Access Journals (Sweden)

    Megan A Carter

    Full Text Available To determine the association between local environmental factors with child weight status in a longitudinal study, using a semi-parametric, group-based method, while also considering social and early life factors.Standardized, directly measured BMI from 4-10 y of age, and group-based trajectory modeling (PROC TRAJ were used to estimate developmental trajectories of weight change in a Québec birth cohort (n = 1,566. Associations between the weight trajectories and living location, social cohesion, disorder, and material and social deprivation were estimated after controlling for social and early life factors.FOUR WEIGHT TRAJECTORY GROUPS WERE ESTIMATED: low-increasing (9.7%; low-medium, accelerating (36.2%; medium-high, increasing (43.0%; and high-stable (11.1%. In the low-increasing and medium-high trajectory groups, living in a semi-urban area was inversely related to weight, while living in a rural area was positively related to weight in the high-stable group. Disorder was inversely related to weight in the low-increasing group only. Other important risk factors for high-stable weight included obesity status of the mother, smoking during pregnancy, and overeating behaviors.In this study, associations between local environment factors and weight differed by trajectory group. Early life factors appear to play a more consistent role in weight status. Further work is needed to determine the influence of place on child weight.

  19. Decreasing the number of small eating occasions (total energy intake) regardless of the time of day may be important to improve diet quality but not adiposity: a cross-sectional study in British children and adolescents.

    Science.gov (United States)

    Murakami, Kentaro; Livingstone, M Barbara E

    2016-01-28

    Evidence of associations between meal frequency (MF) and snack frequency (SF) and diet and obesity in young populations is limited. This cross-sectional study examined MF and SF in relation to dietary intake and adiposity measures in British children aged 4-10 years (n 818) and adolescents aged 11-18 years (n 818). Based on data from a 7-d weighed dietary record, all eating occasions were divided into meals or snacks on the basis of contribution to energy intake (≥15 or total sugar, lower intakes of cereals, fish, meat, protein, PUFA, starch and dietary fibre, and a lower diet quality (assessed by the Mediterranean diet score, except for SF based on energy contribution in adolescents). MF based on time, but not based on energy contribution, was associated with higher intakes of confectionery and total sugar, lower intakes of fish, protein, PUFA and starch, and, only in children, a lower diet quality. All measures of MF and SF showed no association with adiposity measures. In conclusion, this cross-sectional study in British children and adolescents suggests that decreasing the number of small eating occasions (total energy intake) regardless of the time of day may be important to improve diet quality but not adiposity.

  20. Importance of factors determining the low health-related quality of life in people presenting with a diabetic foot ulcer

    DEFF Research Database (Denmark)

    Siersma, V; Thorsen, H; Holstein, P E

    2013-01-01

    To identify the factors responsible for the low health-related quality of life associated with foot ulcers and the relative importance of these factors.......To identify the factors responsible for the low health-related quality of life associated with foot ulcers and the relative importance of these factors....

  1. Investigation of Nuclide Importance to Functional Requirements Related to Transport and Long-Term Storage of LWR Spent Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Broadhead, B.L.

    1995-01-01

    The radionuclide characteristics of light-water-reactor (LWR) spent fuel play key roles in the design and licensing activities for radioactive waste transportation systems, interim storage facilities, and the final repository site. Several areas of analysis require detailed information concerning the time-dependent behavior of radioactive nuclides including (1) neutron/gamma-ray sources for shielding studies, (2) fissile/absorber concentrations for criticality safety determinations, (3) residual decay heat predictions for thermal considerations, and (4) curie and/or radiological toxicity levels for materials assumed to be released into the ground/environment after long periods of time. The crucial nature of the radionuclide predictions over both short and long periods of time has resulted in an increased emphasis on thorough validation for radionuclide generation/depletion codes. Current radionuclide generation/depletion codes have the capability to follow the evolution of some 1600 isotopes during both irradiation and decay time periods. Of these, typically only 10 to 20 nuclides dominate contributions to each analysis area. Thus a quantitative ranking of nuclides over various time periods is desired for each of the analysis areas of shielding, criticality, heat transfer, and environmental dose (radiological toxicity). These rankings should allow for validation and data improvement efforts to be focused only on the most important nuclides. This study investigates the relative importances of the various actinide, fission-product, and light-element isotopes associated with LWR spent fuel with respect to five analysis areas: criticality safety (absorption fractions), shielding (dose rate fractions), curies (fractional curies levels), decay heat (fraction of total watts), and radiological toxicity (fraction of potential committed effective dose equivalent). These rankings are presented for up to six different burnup/enrichment scenarios and at decay times from 2 to

  2. Book Trade Research and Statistics. Prices of U.S. and Foreign Published Materials; Book Title Output and Average Prices: 2001 Final and 2002 Preliminary Figures; Book Sales Statistics, 2002: AAP Preliminary Estimates; U.S. Book Exports and Imports:2002; Number of Book Outlets in the United States and Canada; Review Media Statistics.

    Science.gov (United States)

    Sullivan, Sharon G.; Grabois, Andrew; Greco, Albert N.

    2003-01-01

    Includes six reports related to book trade statistics, including prices of U.S. and foreign materials; book title output and average prices; book sales statistics; book exports and imports; book outlets in the U.S. and Canada; and numbers of books and other media reviewed by major reviewing publications. (LRW)

  3. Fear of Falling in Women with Fibromyalgia and Its Relation with Number of Falls and Balance Performance

    OpenAIRE

    Collado-Mateo, D.; Gallego-Diaz, J. M.; Adsuar, J. C.; Domínguez-Muñoz, F. J.; Olivares, P. R.; Gusi, N.

    2015-01-01

    Objective. To evaluate fear of falling, number of falls, and balance performance in women with FM and to examine the relationship between these variables and others, such as balance performance, quality of life, age, pain, and impact of fibromyalgia. Methods. A total of 240 women participated in this cross-sectional study. Of these, 125 had fibromyalgia. Several variables were assessed: age, fear of falling from 0 to 100, number of falls, body composition, balance performance, lower limb stre...

  4. Changes in the importance of work-related values in Central and Eastern Europe: Slovenia and Hungary against the trend?

    Directory of Open Access Journals (Sweden)

    Agnes Borgulya

    2013-11-01

    Full Text Available The past decade has seen significant political, economic and social changes in several Central and Eastern European (CEE countries. The reasons for the most important transformation processes were the EU membership and the global recession of the late 2000’s. Our study focuses on the effects of these circumstances on people’s work-related values and attitudes. This longitudinal comparative analysis is based on the results of the European Values Study of 1999/2000 and 2008/2009. Our aim is to detect the priorities that determine employees' attitudes to work in ten CEE countries of the EU. Slovenia and Hungary will be paid special attention since these two countries seem not to be followingthe main direction of changes found in the CEE region.

  5. On the relative importance of loads acting on a floating verticalaxis wind turbine system when evaluating the global system response

    DEFF Research Database (Denmark)

    Collu, Maurizio; Borg, Michael; Manuel, Lance

    2016-01-01

    of the VAWT aerodynamic forces, the platform hydrodynamic forces, and the mooring forces. The results help evaluate the relative importance of hydrodynamic with respect to aerodynamic forces, depending on the loading condition. A deeper insight into the aerodynamic forces is provided, which shows the impact...... their potential advantages. Due to the substantial differences between HAWT and VAWT systems, analysis procedures employed for a floating HAWT analyses cannot be extended to use for floating VAWT systems. Here, the main aim is to provide a systematic analysis and comparison of the forces acting on a reference...... by the OC4-Phase II semisubmersible. Using the coupled model of dynamics for VAWT "FloVAWT", the global response of the system is estimated for a set of load cases, allowing the assessment of the contributions of individual force components. In particular, the simulations allow us to assess the impact...

  6. Comparisons of Traffic-Related Ultrafine Particle Number Concentrations Measured in Two Urban Areas by Central, Residential, and Mobile Monitoring.

    Science.gov (United States)

    Simon, Matthew C; Hudda, Neelakshi; Naumova, Elena N; Levy, Jonathan I; Brugge, Doug; Durant, John L

    2017-11-01

    Traffic-related ultrafine particles (UFP; monitoring strategies upon which the models are based have varied between studies. Our study compares particle number concentrations (PNC; a proxy for UFP) measured by three different monitoring approaches (central-site, short-term residential-site, and mobile on-road monitoring) in two study areas in metropolitan Boston (MA, USA). Our objectives were to quantify ambient PNC differences between the three monitoring platforms, compare the temporal patterns and the spatial heterogeneity of PNC between the monitoring platforms, and identify factors that affect correlations across the platforms. We collected >12,000 hours of measurements at the central sites, 1,000 hours of measurements at each of 20 residential sites in the two study areas, and >120 hours of mobile measurements over the course of ~1 year in each study area. Our results show differences between the monitoring strategies: mean one-minute PNC on-roads were higher (64,000 and 32,000 particles/cm 3 in Boston and Chelsea, respectively) compared to central-site measurements (23,000 and 19,000 particles/cm 3 ) and both were higher than at residences (14,000 and 15,000 particles/cm 3 ). Temporal correlations and spatial heterogeneity also differed between the platforms. Temporal correlations were generally highest between central and residential sites, and lowest between central-site and on-road measurements. We observed the greatest spatial heterogeneity across monitoring platforms during the morning rush hours (06:00-09:00) and the lowest during the overnight hours (18:00-06:00). Longer averaging times (days and hours vs. minutes) increased temporal correlations (Pearson correlations were 0.69 and 0.60 vs. 0.39 in Boston; 0.71 and 0.61 vs. 0.45 in Chelsea) and reduced spatial heterogeneity (coefficients of divergence were 0.24 and 0.29 vs. 0.33 in Boston; 0.20 and 0.27 vs. 0.31 in Chelsea). Our results suggest that combining stationary and mobile monitoring may lead

  7. Comparisons of traffic-related ultrafine particle number concentrations measured in two urban areas by central, residential, and mobile monitoring

    Science.gov (United States)

    Simon, Matthew C.; Hudda, Neelakshi; Naumova, Elena N.; Levy, Jonathan I.; Brugge, Doug; Durant, John L.

    2017-11-01

    Traffic-related ultrafine particles (UFP; strategies upon which the models are based have varied between studies. Our study compares particle number concentrations (PNC; a proxy for UFP) measured by three different monitoring approaches (central-site, short-term residential-site, and mobile on-road monitoring) in two study areas in metropolitan Boston (MA, USA). Our objectives were to quantify ambient PNC differences between the three monitoring platforms, compare the temporal patterns and the spatial heterogeneity of PNC between the monitoring platforms, and identify factors that affect correlations across the platforms. We collected >12,000 h of measurements at the central sites, 1000 h of measurements at each of 20 residential sites in the two study areas, and >120 h of mobile measurements over the course of ∼1 year in each study area. Our results show differences between the monitoring strategies: mean 1 min PNC on-roads were higher (64,000 and 32,000 particles/cm3 in Boston and Chelsea, respectively) compared to central-site measurements (23,000 and 19,000 particles/cm3) and both were higher than at residences (14,000 and 15,000 particles/cm3). Temporal correlations and spatial heterogeneity also differed between the platforms. Temporal correlations were generally highest between central and residential sites, and lowest between central-site and on-road measurements. We observed the greatest spatial heterogeneity across monitoring platforms during the morning rush hours (06:00-09:00) and the lowest during the overnight hours (18:00-06:00). Longer averaging times (days and hours vs. minutes) increased temporal correlations (Pearson correlations were 0.69 and 0.60 vs. 0.39 in Boston; 0.71 and 0.61 vs. 0.45 in Chelsea) and reduced spatial heterogeneity (coefficients of divergence were 0.24 and 0.29 vs. 0.33 in Boston; 0.20 and 0.27 vs. 0.31 in Chelsea). Our results suggest that combining stationary and mobile monitoring may lead to improved characterization of

  8. A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism.

    Science.gov (United States)

    Mitozo, Péricles Arruda; de Souza, Luiz Felipe; Loch-Neckel, Gecioni; Flesch, Samira; Maris, Angelica Francesca; Figueiredo, Cláudia Pinto; Dos Santos, Adair Roberto Soares; Farina, Marcelo; Dafre, Alcir Luiz

    2011-07-01

    Cells are endowed with several overlapping peroxide-degrading systems whose relative importance is a matter of debate. In this study, three different sources of neural cells (rat hippocampal slices, rat C6 glioma cells, and mouse N2a neuroblastoma cells) were used as models to understand the relative contributions of individual peroxide-degrading systems. After a pretreatment (30 min) with specific inhibitors, each system was challenged with either H₂O₂ or cumene hydroperoxide (CuOOH), both at 100 μM. Hippocampal slices, C6 cells, and N2a cells showed a decrease in the H₂O₂ decomposition rate (23-28%) by a pretreatment with the catalase inhibitor aminotriazole. The inhibition of glutathione reductase (GR) by BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) significantly decreased H₂O₂ and CuOOH decomposition rates (31-77%). Inhibition of catalase was not as effective as BCNU at decreasing cell viability (MTT assay) and cell permeability or at increasing DNA damage (comet test). Impairing the thioredoxin (Trx)-dependent peroxiredoxin (Prx) recycling by thioredoxin reductase (TrxR) inhibition with auranofin neither potentiated peroxide toxicity nor decreased the peroxide-decomposition rate. The results indicate that neural peroxidatic systems depending on Trx/TrxR for recycling are not as important as those depending on GSH/GR. Dimer formation, which leads to Prx2 inactivation, was observed in hippocampal slices and N2a cells treated with H₂O₂, but not in C6 cells. However, Prx-SO₃ formation, another form of Prx inactivation, was observed in all neural cell types tested, indicating that redox-mediated signaling pathways can be modulated in neural cells. These differences in Prx2 dimerization suggest specific redox regulation mechanisms in glia-derived (C6) compared to neuron-derived (N2a) cells and hippocampal slices. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Deep brain stimulation may reduce the relative risk of clinically important worsening in early stage Parkinson's disease.

    Science.gov (United States)

    Hacker, Mallory L; Tonascia, James; Turchan, Maxim; Currie, Amanda; Heusinkveld, Lauren; Konrad, Peter E; Davis, Thomas L; Neimat, Joseph S; Phibbs, Fenna T; Hedera, Peter; Wang, Lily; Shi, Yaping; Shade, David M; Sternberg, Alice L; Drye, Lea T; Charles, David

    2015-10-01

    The Vanderbilt pilot trial of deep brain stimulation (DBS) in early Parkinson's disease (PD) enrolled patients on medications six months to four years without motor fluctuations or dyskinesias. We conducted a patient-centered analysis based on clinically important worsening of motor symptoms and complications of medical therapy for all subjects and a subset of subjects with a more focused medication duration. Continuous outcomes were also analyzed for this focused cohort. A post hoc analysis was conducted on all subjects from the pilot and a subset of subjects taking PD medications 1-4 years at enrollment. Clinically important worsening is defined as both a ≥ 3 point increase in UPDRS Part III and a ≥ 1 point increase in Part IV. DBS plus optimal drug therapy (DBS + ODT) subjects experienced a 50-80% reduction in the relative risk of worsening after two years. The DBS + ODT group was improved compared to optimal drug therapy (ODT) at each time point on Total UPDRS and Part III (p = 0.04, p = 0.02, respectively, at 24 months). Total UPDRS, Part IV, and PDQ-39 scores significantly worsened in the ODT group after two years (p < 0.003), with no significant change in the DBS + ODT group. DBS + ODT in early PD may reduce the risk of clinically important worsening. These findings further confirm the need to determine if DBS + ODT is superior to medical therapy for managing symptoms, reducing the complications of medications, and improving quality of life. The FDA has approved the conduct of a large-scale, pivotal clinical trial of DBS in early stage PD. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Importance of implementation level when evaluating the effect of the Hi Five Intervention on infectious illness and illness-related absenteeism.

    Science.gov (United States)

    Denbæk, Anne Maj; Andersen, Anette; Bast, Lotus Sofie; Bonnesen, Camilla Thørring; Ersbøll, Annette Kjær; Due, Pernille; Johansen, Anette

    2018-05-01

    There is limited research on the importance of implementation when evaluating the effect of hand hygiene interventions in school settings in developed countries. The aim of this study was to examine the association between an implementation index and the effect of the intervention. The Hi Five Intervention was evaluated in a 3-armed cluster randomized controlled trial involving 43 randomly selected Danish schools. Analyses investigating the association between implementation of the Hi Five Intervention and infectious illness days, infectious illness episodes, illness-related absenteeism, and hand hygiene were carried out in a multilevel model (school, class, and child). The level of implementation was associated with hand hygiene and potentially associated with number of infectious illness days and infectious illness episodes among children. This association was not found for illness-related absenteeism. Classes that succeeded in achieving a high level of implementation of the Hi Five Intervention had a lower number of infectious illness days and infectious illness episodes, suggesting that the Hi Five Intervention, if implemented adequately, may be relevant as a tool to decrease infectious illness in a Danish school setting. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  11. Tooth replacement related to number of natural teeth in a dentate adult population in Bulgaria: a cross-sectional study

    NARCIS (Netherlands)

    Damyanov, N.D.; Witter, D.J.; Bronkhorst, E.M.; Creugers, N.H.J.

    2013-01-01

    PURPOSE: This study aimed to explore the relationships among tooth replacement, number of present natural teeth, and sociodemographic and behavioral factors in an adult population in Bulgaria. MATERIALS AND METHODS: Quota sampling was used to recruit 2,531 dentate subjects aged 20 years and over

  12. Emotional reactions to deviance in groups: the relation between number of angry reactions, felt rejection, and conformity

    NARCIS (Netherlands)

    Heerdink, M.W.; van Kleef, G.A.; Homan, A.C.; Fischer, A.H.

    2015-01-01

    How many members of a group need to express their anger in order to influence a deviant group member’s behavior? In two studies, we examine whether an increase in number of angry group members affects the extent to which a deviant individual feels rejected, and we investigate downstream effects on

  13. The challenge for genetic epidemiologists: how to analyze large numbers of SNPs in relation to complex diseases

    NARCIS (Netherlands)

    Heidema, A.G.; Boer, J.M.A.; Nagelkerke, N.; Mariman, E.C.M.; A, van der D.L.; Feskens, E.J.M.

    2006-01-01

    Genetic epidemiologists have taken the challenge to identify genetic polymorphisms involved in the development of diseases. Many have collected data on large numbers of genetic markers but are not familiar with available methods to assess their association with complex diseases. Statistical methods

  14. The relative importance of impacts from climate change vs. emissions change on air pollution levels in the 21st century

    Directory of Open Access Journals (Sweden)

    G. B. Hedegaard

    2013-04-01

    Full Text Available So far several studies have analysed the impacts of climate change on future air pollution levels. Significant changes due to impacts of climate change have been made clear. Nevertheless, these changes are not yet included in national, regional or global air pollution reduction strategies. The changes in future air pollution levels are caused by both impacts from climate change and anthropogenic emission changes, the importance of which needs to be quantified and compared. In this study we use the Danish Eulerian Hemispheric Model (DEHM driven by meteorological input data from the coupled Atmosphere-Ocean General Circulation Model ECHAM5/MPI-OM and forced with the newly developed RCP4.5 emissions. The relative importance of the climate signal and the signal from changes in anthropogenic emissions on the future ozone, black carbon (BC, total particulate matter with a diameter below 2.5 μm (total PM2.5 including BC, primary organic carbon (OC, mineral dust and secondary inorganic aerosols (SIA and total nitrogen (including NHx + NOy has been determined. For ozone, the impacts of anthropogenic emissions dominate, though a climate penalty is found in the Arctic region and northwestern Europe, where the signal from climate change dampens the effect from the projected emission reductions of anthropogenic ozone precursors. The investigated particles are even more dominated by the impacts from emission changes. For black carbon the emission signal dominates slightly at high latitudes, with an increase up to an order of magnitude larger, close to the emission sources in temperate and subtropical areas. Including all particulate matter with a diameter below 2.5 μm (total PM2.5 enhances the dominance from emissions change. In contrast, total nitrogen (NHx + NOy in parts of the Arctic and at low latitudes is dominated by impacts of climate change.

  15. Determining the relative importance of the mechanisms of behavior change within Alcoholics Anonymous: a multiple mediator analysis.

    Science.gov (United States)

    Kelly, John F; Hoeppner, Bettina; Stout, Robert L; Pagano, Maria

    2012-02-01

    Evidence indicates that Alcoholics Anonymous (AA) participation reduces relapse risk but less is known about the mechanisms through which AA confers this benefit. Initial studies indicate self-efficacy, negative affect, adaptive social networks and spiritual practices are mediators of this effect, but because these have been tested in isolation, their relative importance remains elusive. This study tested multiple mediators simultaneously to help determine the most influential pathways. Prospective, statistically controlled, naturalistic investigation examined the extent to which these previously identified mechanisms mediated AA attendance effects on alcohol outcomes controlling for baseline outcome values, mediators, treatment, and other confounders. Nine clinical sites within the United States. Adults (n = 1726) suffering from alcohol use disorder (AUD) initially enrolled in a randomized study with two arms: aftercare (n = 774); and out-patient (n = 952) comparing three out-patient treatments (Project MATCH). AA attendance during treatment; mediators at 9 months; and outcomes [percentage of days abstinent (PDA) and drinks per drinking day (DDD)] at 15 months. Among out-patients the effect of AA attendance on alcohol outcomes was explained primarily by adaptive social network changes and increases in social abstinence self-efficacy. Among more impaired aftercare patients, in addition to mediation through adaptive network changes and increases in social self-efficacy, AA lead to better outcomes through increasing spirituality/religiosity and by reducing negative affect. The degree to which mediators explained the relationship between AA and outcomes ranged from 43% to 67%. While Alcoholics Anonymous facilitates recovery by mobilizing several processes simultaneously, it is changes in social factors which appear to be of primary importance. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

  16. Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor

    Directory of Open Access Journals (Sweden)

    Kareem Mohideen-Abdul

    2017-06-01

    Full Text Available Most nuclear receptors (NRs bind DNA as dimers, either as hetero- or as homodimers on DNA sequences organized as two half-sites with specific orientation and spacing. The dimerization of NRs on their cognate response elements (REs involves specific protein–DNA and protein–protein interactions. The estrogen-related receptor (ERR belongs to the steroid hormone nuclear receptor (SHR family and shares strong similarity in its DNA-binding domain (DBD with that of the estrogen receptor (ER. In vitro, ERR binds with high affinity inverted repeat REs with a 3-bps spacing (IR3, but in vivo, it preferentially binds to single half-site REs extended at the 5′-end by 3 bp [estrogen-related response element (ERREs], thus explaining why ERR was often inferred as a purely monomeric receptor. Since its C-terminal ligand-binding domain is known to homodimerize with a strong dimer interface, we investigated the binding behavior of the isolated DBDs to different REs using electrophoretic migration, multi-angle static laser light scattering (MALLS, non-denaturing mass spectrometry, and nuclear magnetic resonance. In contrast to ER DBD, ERR DBD binds as a monomer to EREs (IR3, such as the tff1 ERE-IR3, but we identified a DNA sequence composed of an extended half-site embedded within an IR3 element (embedded ERRE/IR3, where stable dimer binding is observed. Using a series of chimera and mutant DNA sequences of ERREs and IR3 REs, we have found the key determinants for the binding of ERR DBD as a dimer. Our results suggest that the sequence-directed DNA shape is more important than the exact nucleotide sequence for the binding of ERR DBD to DNA as a dimer. Our work underlines the importance of the shape-driven DNA readout mechanisms based on minor groove recognition and electrostatic potential. These conclusions may apply not only to ERR but also to other members of the SHR family, such as androgen or glucocorticoid, for which a strong well-conserved half

  17. Importance of relative humidity in the oxidative ageing of organic aerosols: case study of the ozonolysis of maleic acid aerosol

    Directory of Open Access Journals (Sweden)

    P. J. Gallimore

    2011-12-01

    Full Text Available Many important atmospheric aerosol processes depend on the chemical composition of the aerosol, e.g. water uptake and particle cloud interactions. Atmospheric ageing processes, such as oxidation reactions, significantly and continuously change the chemical composition of aerosol particles throughout their lifetime. These ageing processes are often poorly understood. In this study we utilize an aerosol flow tube set up and an ultra-high resolution mass spectrometer to explore the effect of relative humidity (RH in the range of <5–90% on the ozonolysis of maleic acid aerosol which is employed as model organic aerosol system. Due to the slow reaction kinetics relatively high ozone concentrations of 160–200 ppm were used to achieve an appreciable degree of oxidation of maleic acid. The effect of oxidative ageing on the hygroscopicity of maleic acid particles is also investigated using an electrodynamic balance and thermodynamic modelling. RH has a profound effect on the oxidation of maleic acid particles. Very little oxidation is observed at RH < 50% and the only observed reaction products are glyoxylic acid and formic acid. In comparison, when RH > 50% there are about 15 oxidation products identified. This increased oxidation was observed even when the particles were exposed to high humidities long after a low RH ozonolysis reaction. This result might have negative implications for the use of water as an extraction solvent for the analysis of oxidized organic aerosols. These humidity-dependent differences in the composition of the ozonolyzed aerosol demonstrate that water is both a key reactant in the oxidation scheme and a determinant of particle phase and hence diffusivity. The measured chemical composition of the processed aerosol is used to model the hygroscopic growth, which compares favourably with water uptake results from the electrodynamic balance measurements. A reaction mechanism is presented which takes into account the RH dependent

  18. The relative importance of maternal body mass index and glucose levels for prediction of large-for-gestational-age births.

    Science.gov (United States)

    Berntorp, Kerstin; Anderberg, Eva; Claesson, Rickard; Ignell, Claes; Källén, Karin

    2015-10-29

    The risk of gestational diabetes mellitus (GDM) increases substantially with increasing maternal body mass index (BMI). The aim of the present study was to evaluate the relative importance of maternal BMI and glucose levels in prediction of large-for-gestational-age (LGA) births. This observational cohort study was based on women giving birth in southern Sweden during the years 2003-2005. Information on 10,974 pregnancies was retrieved from a population-based perinatal register. A 75-g oral glucose tolerance test (OGTT) was performed in the 28 week of pregnancy for determination of the 2-h plasma glucose concentration. BMI was obtained during the first trimester. The dataset was divided into a development set and a validation set. Using the development set, multiple logistic regression analysis was used to identify maternal characteristics associated with LGA. The prediction of LGA was assessed by receiver-operating characteristic (ROC) curves, with LGA defined as birth weight > +2 standard deviations of the mean. In the final multivariable model including BMI, 2-h glucose level and maternal demographics, the factor most strongly associated with LGA was BMI (odds ratio 1.1, 95% confidence interval [CI] 1.08-1.30). Based on the total dataset, the area under the ROC curve (AUC) of 2-h glucose level to predict LGA was 0.54 (95% CI 0.48-0.60), indicating poor performance. Using the validation database, the AUC for the final multiple model was 0.69 (95% CI 0.66-0.72), which was identical to the AUC retrieved from a model not including 2-h glucose (0.69, 95% CI 0.66-0.72), and larger than from a model including 2-h glucose but not BMI (0.63, 95% CI 0.60-0.67). Both the 2-h glucose level of the OGTT and maternal BMI had a significant effect on the risk of LGA births, but the relative contribution was higher for BMI. The findings highlight the importance of concentrating on healthy body weight in pregnant women and closer monitoring of weight during pregnancy as a

  19. Relative importance of different exposure routes of heavy metals for humans living near a municipal solid waste incinerator

    International Nuclear Information System (INIS)

    Li, Tong; Wan, Yi; Ben, Yujie; Fan, Senrong; Hu, Jianying

    2017-01-01

    The potential health effects of toxic chemicals (e.g. heavy metals) emitted by municipal solid waste incinerators (MSWIs) are of great concern to local residents, however there have been few studies on the contributions of different exposure pathways and their subsequent effects on the body burden of residents living near MSWIs. In this study, multiple exposure routes of heavy metals including Pb, Cr, Cd and Mn were assessed by investigating the metals in foods (such as vegetables, crops, meats and fruits etc.), drinking water, ambient air and soil collected surrounding an MSWI in Shenzhen, south China. Vegetable ingestion played the most important role in the total average daily dose of Pb and Cr, and cereals were the key exposure routes for Mn and Cd. Compound-specific contaminations were observed in the investigated areas, with Pb and Cr present in the surrounding environment, having accumulated to relatively high levels in the local vegetables, and the intake of contaminated vegetable foods greatly influencing the body burden of Pb and Cr. Consistently, significantly high blood concentrations of Pb and Cr were detected in the local residents compared to a referenced population, and a lack of significant differences was found for Cd and Mn. The results possibly suggested that emission of MSWI influenced the external exposure doses of the major pathways of Pb and Cr in this study, and resulted in the different body burden of metals in humans living near a MSWI. MSWI-local food-humans is an important exposure pathway for residents living near MSWI, and thus should not be neglected in developing future strategies and policies to prevent the high risks suffered by residents living near MSWIs. - Highlights: • Vegetable and cereal ingestion were the main contributors to exposure of Pb/Cr and Mn/Cd, respectively. • Concentrations of Pb/Cr in vegetables grown near MSWI were significantly higher. • Blood concentrations of Pb/Cr in populations near MSWI were

  20. Dynamics of energy-related CO2 emissions in China during 1980-2002: the relative importance of energy supply-side and demand-side effects

    International Nuclear Information System (INIS)

    Libo Wu; Kaneko, Shinji; Matsuoka, Shunji

    2006-01-01

    Based on a newly developed model that integrates energy production, transformation and consumption processes, this paper compares the relative importance of some traditionally recognized factors operating on the energy demand side with a body of newly defined factors on the supply side, in terms of their contribution to trends in China's CO 2 emissions related to the total primary energy supply (C-TPES). Before 1996, changes in China's C-TPES were mainly driven by changes on the energy demand side. Factors operating on the energy supply side played trivial roles. During the period 1996-2000, however, increasing demand-side effects declined dramatically and at the same time decreasing effects from supply side expanded significantly. Such changes resulted directly in a decline in the C-TPES. The decreasing effects from international trade as well as statistical imbalances between supply and demand reinforced the declining trend. The shrinkage of demand side effects mainly arose from the slowdown of economic growth and speed of decrease in energy intensity. The expansion of supply-side effects was principally attributed to the speed of decrease in gross unit consumption in transformation sectors, especially in electricity sector. Therefore, the acceleration of efficiency improvements in end-use and transformation sectors accounted for the decline in the C-TPES over the period 1996-2000. (author)

  1. Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.

    Science.gov (United States)

    Ghosh, Debolina; Levault, Kelsey R; Brewer, Gregory J

    2014-08-01

    Aging, a major risk factor in Alzheimer's disease (AD), is associated with an oxidative redox shift, decreased redox buffer protection, and increased free radical reactive oxygen species (ROS) generation, probably linked to mitochondrial dysfunction. While NADH is the ultimate electron donor for many redox reactions, including oxidative phosphorylation, glutathione (GSH) is the major ROS detoxifying redox buffer in the cell. Here, we explored the relative importance of NADH and GSH to neurodegeneration in aging and AD neurons from nontransgenic and 3xTg-AD mice by inhibiting their synthesis to determine whether NADH can compensate for the GSH loss to maintain redox balance. Neurons stressed by either depleting NAD(P)H or GSH indicated that NADH redox control is upstream of GSH levels. Further, although depletion of NAD(P)H or GSH correlated linearly with neuron death, compared with GSH depletion, higher neurodegeneration was observed when NAD(P)H was extrapolated to zero, especially in old age, and in the 3xTg-AD neurons. We also observed an age-dependent loss of gene expression of key redox-dependent biosynthetic enzymes, NAMPT (nicotinamide phosphoribosyltransferase), and NNT (nicotinamide nucleotide transhydrogenase). Moreover, age-related correlations between brain NNT or NAMPT gene expression and NADPH levels suggest that these genes contribute to the age-related declines in NAD(P)H. Our data indicate that in aging and more so in AD-like neurons, NAD(P)H redox control is upstream of GSH and an oxidative redox shift that promotes neurodegeneration. Thus, NAD(P)H generation may be a more efficacious therapeutic target upstream of GSH and ROS. © 2014 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

  2. Two clusters of ciguatera fish poisoning in Paris, France, related to tropical fish imported from the French Caribbean by travelers.

    Science.gov (United States)

    Epelboin, Loïc; Pérignon, Alice; Hossen, Virginie; Vincent, Renaud; Krys, Sophie; Caumes, Eric

    2014-01-01

    Ciguatera fish poisoning (CFP) is a food-borne illness due to the consumption of reef fish containing pathogenic toxins. CFP is endemic to tropical areas and may be described in travelers in non-endemic areas. We describe two clusters of autochthonous cases of CFP in Paris, France. They were related to two fish caught in Guadeloupe (French West Indies) and consumed in Paris after being air-transported in a cooler. In both cases, fish flesh was analyzed and the presence of ciguatoxins by mouse bioassay (MBA) was confirmed. The first cluster involved eight individuals among whom five presented gastrointestinal symptoms and four presented neurological symptoms after consuming barracuda flesh (Sphyraena barracuda). The second cluster involved a couple who consumed a grey snapper (Lutjanus griseus). Most of them consulted at different emergency departments in the region of Paris. CFP may be seen in non-traveler patients outside endemic countries resulting from imported species of fish. Thus, CFP may be undiagnosed as physicians are not aware of this tropical disease outside endemic countries. The detection of ciguatoxins by MBA in the French National Reference Laboratory is useful in the confirmation of the diagnosis. © 2014 International Society of Travel Medicine.

  3. Nutritional support of estuary perch ( Macquaria colonorum) in a temperate Australian inlet: Evaluating the relative importance of invasive Spartina

    Science.gov (United States)

    Hindell, J. S.; Warry, F. Y.

    2010-12-01

    The invasive saltmarsh grass Spartina is widely considered a threat to the health of coastal ecosystems in south-eastern Australia, however, the ecological impacts of Spartina on estuarine communities are poorly understood. The largest infestation of Spartina in Victoria occurs in Anderson Inlet. The relative contribution of Spartina, vs. non-invasive autotrophs, to the nutrition of an estuarine fish, Macquaria colonorum was assessed using stable isotopes and gut content analyses. The δ 13C and δ 15N compositions of autotrophs and M. colonorum varied spatially across the study area. Based on gut content analyses, adults and juveniles were between two and three trophic levels above autotrophs. Isosource modelling of δ 13C signatures, suggested several autotrophs contributed to the nutrition of M. colonorum with a combination of seagrass and Spartina likely important contributors, particularly for adults. Isotopic sulphur was subsequently used to distinguish between seagrass and Spartina. Modelling of δ 13C and δ 34S signatures of M. colonorum and a subset of autotrophs again indicated a combination of seagrass and Spartina was likely a major contributor to nutritional support of M. colonorum. Given the limited areal extent of seagrass within Anderson Inlet, current Spartina eradication programs may compromise the nutritional support of M. colonorum.

  4. Community regulation: the relative importance of recruitment and predation intensity of an intertidal community dominant in a seascape context.

    Science.gov (United States)

    Rilov, Gil; Schiel, David R

    2011-01-01

    Predicting the strength and context-dependency of species interactions across multiple scales is a core area in ecology. This is especially challenging in the marine environment, where populations of most predators and prey are generally open, because of their pelagic larval phase, and recruitment of both is highly variable. In this study we use a comparative-experimental approach on small and large spatial scales to test the relationship between predation intensity and prey recruitment and their relative importance in shaping populations of a dominant rocky intertidal space occupier, mussels, in the context of seascape (availability of nearby subtidal reef habitat). Predation intensity on transplanted mussels was tested inside and outside cages and recruitment was measured with standard larval settlement collectors. We found that on intertidal rocky benches with contiguous subtidal reefs in New Zealand, mussel larval recruitment is usually low but predation on recruits by subtidal consumers (fish, crabs) is intense during high tide. On nearby intertidal rocky benches with adjacent sandy subtidal habitats, larval recruitment is usually greater but subtidal predators are typically rare and predation is weaker. Multiple regression analysis showed that predation intensity accounts for most of the variability in the abundance of adult mussels compared to recruitment. This seascape-dependent, predation-recruitment relationship could scale up to explain regional community variability. We argue that community ecology models should include seascape context-dependency and its effects on recruitment and species interactions for better predictions of coastal community dynamics and structure.

  5. Relative importance of local habitat complexity and regional factors for assemblages of oribatid mites (Acari: Oribatida) in Sphagnum peat bogs.

    Science.gov (United States)

    Minor, M A; Ermilov, S G; Philippov, D A; Prokin, A A

    2016-11-01

    We investigated communities of oribatid mites in five peat bogs in the north-west of the East European plain. We aimed to determine the extent to which geographic factors (latitude, separation distance), local environment (Sphagnum moss species, ground water level, biogeochemistry) and local habitat complexity (diversity of vascular plants and bryophytes in the surrounding plant community) influence diversity and community composition of Oribatida. There was a significant north-to-south increase in Oribatida abundance. In the variance partitioning, spatial factors explained 33.1 % of variability in abundance across samples; none of the environmental factors were significant. Across all bogs, Oribatida species richness and community composition were similar in Sphagnum rubellum and Sphagnum magellanicum, but significantly different and less diverse in Sphagnum cuspidatum. Sphagnum microhabitat explained 52.2 % of variability in Oribatida species richness, whereas spatial variables explained only 8.7 %. There was no distance decay in community similarity between bogs with increased geographical distance. The environmental variables explained 34.9 % of the variance in community structure, with vascular plants diversity, bryophytes diversity, and ground water level all contributing significantly; spatial variables explained 15.1 % of the total variance. Overall, only 50 % of the Oribatida community variance was explained by the spatial structure and environmental variables. We discuss relative importance of spatial and local environmental factors, and make general inferences about the formation of fauna in Sphagnum bogs.

  6. Community regulation: the relative importance of recruitment and predation intensity of an intertidal community dominant in a seascape context.

    Directory of Open Access Journals (Sweden)

    Gil Rilov

    Full Text Available Predicting the strength and context-dependency of species interactions across multiple scales is a core area in ecology. This is especially challenging in the marine environment, where populations of most predators and prey are generally open, because of their pelagic larval phase, and recruitment of both is highly variable. In this study we use a comparative-experimental approach on small and large spatial scales to test the relationship between predation intensity and prey recruitment and their relative importance in shaping populations of a dominant rocky intertidal space occupier, mussels, in the context of seascape (availability of nearby subtidal reef habitat. Predation intensity on transplanted mussels was tested inside and outside cages and recruitment was measured with standard larval settlement collectors. We found that on intertidal rocky benches with contiguous subtidal reefs in New Zealand, mussel larval recruitment is usually low but predation on recruits by subtidal consumers (fish, crabs is intense during high tide. On nearby intertidal rocky benches with adjacent sandy subtidal habitats, larval recruitment is usually greater but subtidal predators are typically rare and predation is weaker. Multiple regression analysis showed that predation intensity accounts for most of the variability in the abundance of adult mussels compared to recruitment. This seascape-dependent, predation-recruitment relationship could scale up to explain regional community variability. We argue that community ecology models should include seascape context-dependency and its effects on recruitment and species interactions for better predictions of coastal community dynamics and structure.

  7. Relative importance of deterministic and stochastic processes in driving arbuscular mycorrhizal fungal assemblage during the spreading of a toxic plant.

    Directory of Open Access Journals (Sweden)

    Guoxi Shi

    Full Text Available Both deterministic and stochastic processes are expected to drive the assemblages of arbuscular mycorrhizal (AM fungi, but little is known about the relative importance of these processes during the spreading of toxic plants. Here, the species composition and phylogenetic structure of AM fungal communities colonizing the roots of a toxic plant, Ligularia virgaurea, and its neighborhood plants, were analyzed in patches with different individual densities of L. virgaurea (represents the spreading degree. Community compositions of AM fungi in both root systems were changed significantly by the L. virgaurea spreading, and also these communities fitted the neutral model very well. AM fungal communities in patches with absence and presence of L. virgaurea were phylogenetically random and clustered, respectively, suggesting that the principal ecological process determining AM fungal assemblage shifted from stochastic process to environmental filtering when this toxic plant was present. Our results indicate that deterministic and stochastic processes together determine the assemblage of AM fungi, but the dominant process would be changed by the spreading of toxic plants, and suggest that the spreading of toxic plants in alpine meadow ecosystems might be involving the mycorrhizal symbionts.

  8. Disparities in lifestyle habits and health related factors of Montreal immigrants: is immigration an important exposure variable in public health?

    Science.gov (United States)

    Meshefedjian, Garbis A; Leaune, Viviane; Simoneau, Marie-Ève; Drouin, Mylène

    2014-10-01

    Study disparities in lifestyle habits and health characteristics of Canadian born population and immigrants with different duration of residence. Data are extracted from 2009 to 2010 public use micro-data files of Canadian Community Health Survey representing about 1.5 million people. Sixty-one percent of the study sample was born in Canada; 49 % males and 59 % below age 50. Amongst lifestyle habits, recent immigrants were less likely to be regular smokers, RR (95 % CI) 0.56 (0.36-0.88) and frequent consumers of alcohol 0.49 (0.27-0.89), but more likely to consume less fruits and vegetables 1.26 (1.04-1.53) than those born in Canada. Amongst health related factors, recent immigrants were less likely to be overweight 0.79 (0.62-0.99) and suffer from chronic diseases 0.59 (0.44-0.80), but more likely to have limited access to family medicine 1.24 (1.04-1.47) than Canada-born population. Immigration status is an important population characteristic which influenced distribution of health indicators. Prevention and promotion strategies should consider immigration status as an exposure variable in the development and implementation of public health programs.

  9. Relative Importance of Various Sources of Defect-Producing Hydrogen Introduced into Steel During Application of Vitreous Coatings

    Science.gov (United States)

    Moore, Dwight G; Mason, Mary A; Harrison, William N

    1953-01-01

    When porcelain enamels or vitreous-type ceramic coatings are applied to ferrous metals, there is believed to be an evolution of hydrogen gas both during and after the firing operation. At elevated temperatures rapid evolution may result in blistering while if hydrogen becomes trapped in the steel during the rapid cooling following the firing operation gas pressures may be generated at the coating-metal interface and flakes of the coating literally blown off the metal. To determine experimentally the relative importance of the principal sources of the hydrogen causing the defects, a procedure was devised in which heavy hydrogen (deuterium) was substituted in turn for regular hydrogen in each of five possible hydrogen-producing operations in the coating process. The findings of the study were as follows: (1) the principal source of the defect-producing hydrogen was the dissolved water present in the enamel frit that was incorporated into the coating. (2) the acid pickling, the milling water, the chemically combined water in the clay, and the quenching water were all minor sources of defect-producing hydrogen under the test conditions used. Confirming experiments showed that fishscaling could be eliminated by using a water-free coating.

  10. Importance of stress-response genes to the survival of airborne Escherichia coli under different levels of relative humidity.

    Science.gov (United States)

    Ng, Tsz Wai; Chan, Wing Lam; Lai, Ka Man

    2017-12-01

    Other than the needs for infection control to investigate the survival and inactivation of airborne bacterial pathogens, there has been a growing interest in exploring bacterial communities in the air and the effect of environmental variables on them. However, the innate biological mechanism influencing the bacterial viability is still unclear. In this study, a mutant-based approach, using Escherichia coli as a model, was used to prove the concept that common stress-response genes are important for airborne survival of bacteria. Mutants with a single gene knockout that are known to respond to general stress (rpoS) and oxidative stress (oxyR, soxR) were selected in the study. Low relative humidity (RH), 30-40% was more detrimental to the bacteria than high RH, >90%. The log reduction of ∆rpoS was always higher than that of the parental strain at all RH levels but the ∆oxyR had a higher log reduction than the parental strain at intermediate RH only. ∆soxR had the same viability compared to the parental strain at all RH levels. The results hint that although different types and levels of stress are produced under different RH conditions, stress-response genes always play a role in the bacterial viability. This study is the first reporting the association between stress-response genes and viability of airborne bacteria.

  11. Relative importance of driving force and electrostatic interactions in the reduction of multihaem cytochromes by small molecules.

    Science.gov (United States)

    Quintas, Pedro O; Cepeda, Andreia P; Borges, Nuno; Catarino, Teresa; Turner, David L

    2013-06-01

    Multihaem cytochromes are essential to the energetics of organisms capable of bioremediation and energy production. The haems in several of these cytochromes have been discriminated thermodynamically and their individual rates of reduction by small electron donors were characterized. The kinetic characterization of individual haems used the Marcus theory of electron transfer and assumed that the rates of reduction of each haem by sodium dithionite depend only on the driving force, while electrostatic interactions were neglected. To determine the relative importance of these factors in controlling the rates, we studied the effect of ionic strength on the redox potential and the rate of reduction by dithionite of native Methylophilus methylotrophus cytochrome c″ and three mutants at different pH values. We found that the main factor determining the rate is the driving force and that Marcus theory describes this satisfactorily. This validates the method of the simultaneous fitting of kinetic and thermodynamic data in multihaem cytochromes and opens the way for further investigation into the mechanisms of these proteins. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. The Relative Importance of Random Error and Observation Frequency in Detecting Trends in Upper Tropospheric Water Vapor

    Science.gov (United States)

    Whiteman, David N.; Vermeesch, Kevin C.; Oman, Luke D.; Weatherhead, Elizabeth C.

    2011-01-01

    Recent published work assessed the amount of time to detect trends in atmospheric water vapor over the coming century. We address the same question and conclude that under the most optimistic scenarios and assuming perfect data (i.e., observations with no measurement uncertainty) the time to detect trends will be at least 12 years at approximately 200 hPa in the upper troposphere. Our times to detect trends are therefore shorter than those recently reported and this difference is affected by data sources used, method of processing the data, geographic location and pressure level in the atmosphere where the analyses were performed. We then consider the question of how instrumental uncertainty plays into the assessment of time to detect trends. We conclude that due to the high natural variability in atmospheric water vapor, the amount of time to detect trends in the upper troposphere is relatively insensitive to instrumental random uncertainty and that it is much more important to increase the frequency of measurement than to decrease the random error in the measurement. This is put in the context of international networks such as the Global Climate Observing System (GCOS) Reference Upper-Air Network (GRUAN) and the Network for the Detection of Atmospheric Composition Change (NDACC) that are tasked with developing time series of climate quality water vapor data.

  13. Importance of Sulfate Aerosol in Evaluating the Relative Contributions of Regional Emissions to the Historical Global Temperature Change

    International Nuclear Information System (INIS)

    Andronova, N.; Schlesinger, M.

    2004-01-01

    During the negotiations of the Kyoto Protocol the delegation of Brazil presented an approach for distributing the burden of emissions reductions among the Parties based on the effect of their cumulative historical emissions on the global-average near-surface temperature. The Letter to the Parties does not limit the emissions to be considered to be only greenhouse gas (GHG) emissions. Thus, in this paper we explore the importance of anthropogenic SOx emissions that are converted to sulfate aerosol in the atmosphere, together with the cumulative greenhouse gas emissions, in attributing historical temperature change. We use historical emissions and our simple climate model to estimate the relative contributions to global warming of the regional emissions by four Parties: OECD90, Africa and Latin America, Asia, and Eastern Europe and the Former Soviet Union. Our results show that for most Parties the large warming contributed by their GHG emissions is largely offset by the correspondingly large cooling by their SOx emissions. Thus, OECD90 has become the dominant contributor to recent global warming following its large reduction in SOx emissions after 1980

  14. The assessment of science: the relative merits of post-publication review, the impact factor, and the number of citations.

    Science.gov (United States)

    Eyre-Walker, Adam; Stoletzki, Nina

    2013-10-01

    The assessment of scientific publications is an integral part of the scientific process. Here we investigate three methods of assessing the merit of a scientific paper: subjective post-publication peer review, the number of citations gained by a paper, and the impact factor of the journal in which the article was published. We investigate these methods using two datasets in which subjective post-publication assessments of scientific publications have been made by experts. We find that there are moderate, but statistically significant, correlations between assessor scores, when two assessors have rated the same paper, and between assessor score and the number of citations a paper accrues. However, we show that assessor score depends strongly on the journal in which the paper is published, and that assessors tend to over-rate papers published in journals with high impact factors. If we control for this bias, we find that the correlation between assessor scores and between assessor score and the number of citations is weak, suggesting that scientists have little ability to judge either the intrinsic merit of a paper or its likely impact. We also show that the number of citations a paper receives is an extremely error-prone measure of scientific merit. Finally, we argue that the impact factor is likely to be a poor measure of merit, since it depends on subjective assessment. We conclude that the three measures of scientific merit considered here are poor; in particular subjective assessments are an error-prone, biased, and expensive method by which to assess merit. We argue that the impact factor may be the most satisfactory of the methods we have considered, since it is a form of pre-publication review. However, we emphasise that it is likely to be a very error-prone measure of merit that is qualitative, not quantitative.

  15. Antibodies to hepatitis A antigen in relation to the number of lifetime sexual partners in patients attending an STD clinic.

    OpenAIRE

    McFarlane, E S; Embil, J A; Manuel, F R; Thiébaux, H J

    1981-01-01

    Samples of serum from 421 patients attending a clinic for sexually transmitted diseases (STDs) were tested by radioimmunoassay for determination of the prevalence of antibodies to hepatitis A antigen (anti-HA). It was found that 42 . 4% of 33 homosexual men, 39 . 4% of 218 heterosexual men, and 38 . 8% of 170 female patients had positive results for anti-HA. The association between serological results and data on STD patients, using the variables of age, sexual type and preference, number of ...

  16. Assessing the relative importance of local and regional processes on the survival of a threatened salmon population.

    Science.gov (United States)

    Miller, Jessica A; Teel, David J; Peterson, William T; Baptista, Antonio M

    2014-01-01

    Research on regulatory mechanisms in biological populations often focuses on environmental covariates. An integrated approach that combines environmental indices with organismal-level information can provide additional insight on regulatory mechanisms. Survival of spring/summer Snake River Chinook salmon (Oncorhynchus tshawytscha) is consistently low whereas some adjacent populations with similar life histories experience greater survival. It is not known if populations with differential survival respond similarly during early marine residence, a critical period in the life history. Ocean collections, genetic stock identification, and otolith analyses were combined to evaluate the growth-mortality and match-mismatch hypotheses during early marine residence of spring/summer Snake River Chinook salmon. Interannual variation in juvenile attributes, including size at marine entry and marine growth rate, was compared with estimates of survival and physical and biological metrics. Multiple linear regression and multi-model inference were used to evaluate the relative importance of biological and physical metrics in explaining interannual variation in survival. There was relatively weak support for the match-mismatch hypothesis and stronger evidence for the growth-mortality hypothesis. Marine growth and size at capture were strongly, positively related to survival, a finding similar to spring Chinook salmon from the Mid-Upper Columbia River. In hindcast models, basin-scale indices (Pacific Decadal Oscillation (PDO) and the North Pacific Gyre Oscillation (NPGO)) and biological indices (juvenile salmon catch-per-unit-effort (CPUE) and a copepod community index (CCI)) accounted for substantial and similar portions of variation in survival for juvenile emigration years 1998-2008 (R2>0.70). However, in forecast models for emigration years 2009-2011, there was an increasing discrepancy between predictions based on the PDO (50-448% of observed value) compared with those based on

  17. Assessing the relative importance of local and regional processes on the survival of a threatened salmon population.

    Directory of Open Access Journals (Sweden)

    Jessica A Miller

    Full Text Available Research on regulatory mechanisms in biological populations often focuses on environmental covariates. An integrated approach that combines environmental indices with organismal-level information can provide additional insight on regulatory mechanisms. Survival of spring/summer Snake River Chinook salmon (Oncorhynchus tshawytscha is consistently low whereas some adjacent populations with similar life histories experience greater survival. It is not known if populations with differential survival respond similarly during early marine residence, a critical period in the life history. Ocean collections, genetic stock identification, and otolith analyses were combined to evaluate the growth-mortality and match-mismatch hypotheses during early marine residence of spring/summer Snake River Chinook salmon. Interannual variation in juvenile attributes, including size at marine entry and marine growth rate, was compared with estimates of survival and physical and biological metrics. Multiple linear regression and multi-model inference were used to evaluate the relative importance of biological and physical metrics in explaining interannual variation in survival. There was relatively weak support for the match-mismatch hypothesis and stronger evidence for the growth-mortality hypothesis. Marine growth and size at capture were strongly, positively related to survival, a finding similar to spring Chinook salmon from the Mid-Upper Columbia River. In hindcast models, basin-scale indices (Pacific Decadal Oscillation (PDO and the North Pacific Gyre Oscillation (NPGO and biological indices (juvenile salmon catch-per-unit-effort (CPUE and a copepod community index (CCI accounted for substantial and similar portions of variation in survival for juvenile emigration years 1998-2008 (R2>0.70. However, in forecast models for emigration years 2009-2011, there was an increasing discrepancy between predictions based on the PDO (50-448% of observed value compared with

  18. Relating the octane numbers of fuels to ignition delay times measured in an ignition quality tester (IQT)

    KAUST Repository

    Naser, Nimal

    2016-09-21

    A methodology for estimating the octane index (OI), the research octane number (RON) and the motor octane number (MON) using ignition delay times from a constant volume combustion chamber with liquid fuel injection is proposed by adopting an ignition quality tester. A baseline data of ignition delay times were determined using an ignition quality tester at a charge pressure of 21.3 bar between 770 and 850 K and an equivalence ratio of 0.7 for various primary reference fuels (PRFs, mixtures of isooctane and n-heptane). Our methodology was developed using ignition delay times for toluene reference fuels (mixtures of toluene and n-heptane). A correlation between the OI and the ignition delay time at the initial charge temperature enabled the OI of non-PRFs to be predicted at specified temperatures. The methodology was validated using ignition delay times for toluene primary reference fuels (ternary mixtures of toluene, iso-octane, and n-heptane), fuels for advanced combustion engines (FACE) gasolines, and certification gasolines. Using this methodology, the RON, the MON, and the octane sensitivity were estimated in agreement with values obtained from standard test methods. A correlation between derived cetane number and RON is also provided. (C) 2016 Elsevier Ltd. All rights reserved.

  19. The Role of Equivalence and Order Relations in the Development and Coordination of the Concepts of Unit Size and Number of Units in Selected Conservation Type Measurement Problems.

    Science.gov (United States)

    Carpenter, Thomas P.

    The major purpose of this study was 1) to investigate the development of the concept of a unit of measure and the coordination of unit size and the number of units 2) to relate this development to the development of conservation and 3) to determine the role of equivalence and nonequivalence relations in certain conservation and measurement…

  20. Visual acuity and contrast sensitivity are two important factors affecting vision-related quality of life in advanced age-related macular degeneration.

    Science.gov (United States)

    Roh, Miin; Selivanova, Alexandra; Shin, Hyun Joon; Miller, Joan W; Jackson, Mary Lou

    2018-01-01

    Vision loss from age-related macular degeneration (AMD) has a profound effect on vision-related quality of life (VRQoL). The pupose of this study is to identify clinical factors associated with VRQoL using the Rasch- calibrated NEI VFQ-25 scales in bilateral advanced AMD patients. We retrospectively reviewed 47 patients (mean age 83.2 years) with bilateral advanced AMD. Clinical assessment included age, gender, type of AMD, high contrast visual acuity (VA), history of medical conditions, contrast sensitivity (CS), central visual field loss, report of Charles Bonnet Syndrome, current treatment for AMD and Rasch-calibrated NEI VFQ-25 visual function and socioemotional function scales. The NEI VFQ visual function scale includes items of general vision, peripheral vision, distance vision and near vision-related activity while the socioemotional function scale includes items of vision related-social functioning, role difficulties, dependency, and mental health. Multiple regression analysis (structural regression model) was performed using fixed item parameters obtained from the one-parameter item response theory model. Multivariate analysis showed that high contrast VA and CS were two factors influencing VRQoL visual function scale (β = -0.25, 95% CI-0.37 to -0.12, p<0.001 and β = 0.35, 95% CI 0.25 to 0.46, p<0.001) and socioemontional functioning scale (β = -0.2, 95% CI -0.37 to -0.03, p = 0.023, and β = 0.3, 95% CI 0.18 to 0.43, p = 0.001). Central visual field loss was not assoicated with either VRQoL visual or socioemontional functioning scale (β = -0.08, 95% CI-0.28 to 0.12,p = 0.44 and β = -0.09, 95% CI -0.03 to 0.16, p = 0.50, respectively). In patients with vision impairment secondary to bilateral advanced AMD, high contrast VA and CS are two important factors affecting VRQoL.

  1. Visual acuity and contrast sensitivity are two important factors affecting vision-related quality of life in advanced age-related macular degeneration

    Science.gov (United States)

    Selivanova, Alexandra; Shin, Hyun Joon; Miller, Joan W.; Jackson, Mary Lou

    2018-01-01

    Purpose Vision loss from age-related macular degeneration (AMD) has a profound effect on vision-related quality of life (VRQoL). The pupose of this study is to identify clinical factors associated with VRQoL using the Rasch- calibrated NEI VFQ-25 scales in bilateral advanced AMD patients. Methods We retrospectively reviewed 47 patients (mean age 83.2 years) with bilateral advanced AMD. Clinical assessment included age, gender, type of AMD, high contrast visual acuity (VA), history of medical conditions, contrast sensitivity (CS), central visual field loss, report of Charles Bonnet Syndrome, current treatment for AMD and Rasch-calibrated NEI VFQ-25 visual function and socioemotional function scales. The NEI VFQ visual function scale includes items of general vision, peripheral vision, distance vision and near vision-related activity while the socioemotional function scale includes items of vision related-social functioning, role difficulties, dependency, and mental health. Multiple regression analysis (structural regression model) was performed using fixed item parameters obtained from the one-parameter item response theory model. Results Multivariate analysis showed that high contrast VA and CS were two factors influencing VRQoL visual function scale (β = -0.25, 95% CI-0.37 to -0.12, p<0.001 and β = 0.35, 95% CI 0.25 to 0.46, p<0.001) and socioemontional functioning scale (β = -0.2, 95% CI -0.37 to -0.03, p = 0.023, and β = 0.3, 95% CI 0.18 to 0.43, p = 0.001). Central visual field loss was not assoicated with either VRQoL visual or socioemontional functioning scale (β = -0.08, 95% CI-0.28 to 0.12,p = 0.44 and β = -0.09, 95% CI -0.03 to 0.16, p = 0.50, respectively). Conclusion In patients with vision impairment secondary to bilateral advanced AMD, high contrast VA and CS are two important factors affecting VRQoL. PMID:29746512

  2. Gender & Racial Inequality at Work: The Sources & Consequences of Job Segregation. Cornell Studies in Industrial and Labor Relations Number 27.

    Science.gov (United States)

    Tomaskovic-Devey, Donald

    This book proposes that job-level segregation by sex and race is a fundamentally important source of black-white and male-female inequalities in employment. Drawing on the North Carolina Employment and Health Survey, the first general population survey that measures the gender and racial compositions of jobs, the book explores this thesis in the…

  3. Fish assemblages in coastal lagoons in land-uplift succession: The relative importance of local and regional environmental gradients

    Science.gov (United States)

    Snickars, Martin; Sandström, Alfred; Lappalainen, Antti; Mattila, Johanna; Rosqvist, Kajsa; Urho, Lauri

    2009-01-01

    . We suggest that this difference in the relative importance of the two gradients depending on the level of respective gradient ultimately forms these heterogeneous coastal habitats in a successional landscape. Rutilus rutilus and P. fluviatilis were responsible for large parts of the assemblage patterns. Although sympatric due to similar habitat requirements, differences in dispersal capability, competitive ability and predation vulnerability may add explanation to detected differences in distribution and abundance in these two species in an open system. Our results also stress the structuring role of vegetation in terms of total coverage and species composition, as these two aspects of macrophyte diversity may act as complementary habitat modifiers across gradients of physical harshness.

  4. Risk factors for chronic undernutrition among children in India: Estimating relative importance, population attributable risk and fractions.

    Science.gov (United States)

    Corsi, Daniel J; Mejía-Guevara, Iván; Subramanian, S V

    2016-05-01

    Nearly 40% of the world's stunted children live in India and the prevalence of undernutrition has been persistently high in recent decades. Given numerous available interventions for reducing undernutrition in children, it is not clear of the relative importance of each within a multifactorial framework. We assess the simultaneous contribution of 15 known risk factors for child chronic undernutrition in India. Data are from the 3rd Indian National Family Health Survey (NFHS-3), a nationally representative cross-sectional survey undertaken in 2005-2006. The study population consisted of children aged 6-59 months [n = 26,842 (stunting/low height-for-age), n = 27,483 (underweight/low weight-for-age)]. Risk factors examined for their association with undernutrition were: vitamin A supplementation, vaccination, use of iodized salt, household air quality, improved sanitary facilities, safe disposal of stools, improved drinking water, prevalence of infectious disease, initiation of breastfeeding, dietary diversity, age at marriage, maternal BMI, height, education, and household wealth. Age/sex-adjusted and multivariable adjusted effect sizes (odds ratios) were calculated for risk factors along with Population Attributable Risks (PAR) and Fractions (PAF) using logistic regression. In the mutually adjusted models, the five most important predictors of childhood stunting/underweight were short maternal stature, mother having no education, households in lowest wealth quintile, poor dietary diversity, and maternal underweight. These five factors had a combined PAR of 67.2% (95% CI: 63.3-70.7) and 69.7% (95% CI: 66.3-72.8) for stunting and underweight, respectively. The remaining factors were associated with a combined PAR of 11.7% (95% CI: 6.0-17.4) and 15.1% (95% CI: 8.9-21.3) for stunting and underweight, respectively. Implementing strategies focused on broader progress on social circumstances and infrastructural domains as well as investments in nutrition specific

  5. High frequency of rare copy number variants affecting functionally related genes in patients with structural brain malformations

    DEFF Research Database (Denmark)

    Kariminejad, Roxana; Lind-Thomsen, Allan; Tümer, Zeynep

    2011-01-01

    ) to investigate copy number variants (CNVs) in a cohort of 169 patients with various structural brain malformations including lissencephaly, polymicrogyria, focal cortical dysplasia, and corpus callosum agenesis. The majority of the patients had intellectual disabilities (ID) and suffered from symptomatic...... that genes involved in "axonal transport," "cation transmembrane transporter activity," and the "c-Jun N-terminal kinase (JNK) cascade" play a significant role in the etiology of brain malformations. This is to the best of our knowledge the first systematic study of CNVs in patients with structural brain...

  6. A STUDY TO DETERMINE CO‐RELATION BETWEEN DISEASE BURDEN, NUMBER OF CLINICAL TRIALS DONE AND SUCCESS RATES FOR GERMANY AND INDIA.

    Directory of Open Access Journals (Sweden)

    Dnyanesh Limaye

    2014-12-01

    Full Text Available The drugs we use to treat any condition – from an innocuous cough to a lifethreatening cancer – are the outcome of painstaking human clinical trials. These trials are the only way to credibly determine the safety and efficacy of drugs. In recent years there has been a clear shift in clinical trial sites from core developed countries like USA, European countries to developing countries like India, China, South American countries. This shift is related to challenges and opportunities like costs of trials, recruitment issues, and regulatory challenges in developed vs. developing countries. Developing countries and developed countries have their unique disease burden patterns based on various parameters like but not limited to age, health care facilities, health insurance, sanitary conditions, environmental issues, education, nutrition and GDP. Previous studies have reported that many of the important global diseases are not much explored in clinical trials and many published clinical trials have very less international health relevance. This study was aimed at finding the correlation between disease burdens, number of clinical trials done and trial success rates. We compared 2005-2010 Global Burden of Disease data for Germany, India and number of clinical trials from clinicaltrials.gov database done in the same period. Our findings indicated that there was a good correlation between the disease burden and clinical trials for Germany in 2005 and 2010. For India in 2005 there was a moderate positive correlation, 2010 data showed the improvement in India in terms of match between disease burden and clinical Trials. But careful observation of the data shows still a need for more trials on Communicable, maternal, neonatal and nutritional disorders.

  7. Dynamics in copy numbers of five plasmids of a dairy Lactococcus lactis in dairy-related conditions including near-zero growth rates.

    Science.gov (United States)

    van Mastrigt, Oscar; Lommers, Marcel M A N; de Vries, Yorick C; Abee, Tjakko; Smid, Eddy J

    2018-03-23

    Lactic acid bacteria can carry multiple plasmids affecting their performance in dairy fermentations. The expression of plasmid-encoded genes and the activity of the corresponding proteins is severely affected by changes in the number of plasmid copies. We studied the impact of growth rate on dynamics of plasmid copy numbers at high growth rates in chemostat cultures and down to near-zero growth rates in retentostat cultures. Five plasmids of the dairy strain Lactococcus lactis FM03-V1 were selected which varied in size (3 to 39 kb), in replication mechanism (theta or rolling-circle) and in putative (dairy-associated) functions. Copy numbers ranged from 1.5 to 40.5 and the copy number of theta-type replicating plasmids were negatively correlated to the plasmid size. Despite the extremely wide range of growth rates (0.0003 h -1 to 0.6 h -1 ), copy numbers of the five plasmids were stable and only slightly increased at near-zero growth rates showing that the plasmid replication rate was strictly controlled. One low-copy number plasmid, carrying a large exopolysaccharide gene cluster, was segregationally unstable during retentostat cultivations reflected in complete loss of the plasmid in one of the retentostat cultures. The copy number of the five plasmids was also hardly affected by varying the pH value, nutrient limitation or presence of citrate (maximum 2.2-fold) signifying the stability in copy number of the plasmids. Importance Lactococcus lactis is extensively used in starter cultures for dairy fermentations. Important traits for growth and survival of L. lactis in dairy fermentations are encoded by genes located on plasmids, such as genes involved in lactose and citrate metabolism, protein degradation and oligopeptide uptake and bacteriophage resistance. Because the number of plasmid copies could affect the expression of plasmid-encoded genes, it is important to know the factors that influence the plasmid copy numbers. We monitored plasmid copy numbers of L

  8. Relative importance of H2 and H2S as energy sources for primary production in geothermal springs.

    Science.gov (United States)

    D'Imperio, Seth; Lehr, Corinne R; Oduro, Harry; Druschel, Greg; Kühl, Michael; McDermott, Timothy R

    2008-09-01

    Geothermal waters contain numerous potential electron donors capable of supporting chemolithotrophy-based primary production. Thermodynamic predictions of energy yields for specific electron donor and acceptor pairs in such systems are available, although direct assessments of these predictions are rare. This study assessed the relative importance of dissolved H(2) and H(2)S as energy sources for the support of chemolithotrophic metabolism in an acidic geothermal spring in Yellowstone National Park. H(2)S and H(2) concentration gradients were observed in the outflow channel, and vertical H(2)S and O(2) gradients were evident within the microbial mat. H(2)S levels and microbial consumption rates were approximately three orders of magnitude greater than those of H(2). Hydrogenobaculum-like organisms dominated the bacterial component of the microbial community, and isolates representing three distinct 16S rRNA gene phylotypes (phylotype = 100% identity) were isolated and characterized. Within a phylotype, O(2) requirements varied, as did energy source utilization: some isolates could grow only with H(2)S, some only with H(2), while others could utilize either as an energy source. These metabolic phenotypes were consistent with in situ geochemical conditions measured using aqueous chemical analysis and in-field measurements made by using gas chromatography and microelectrodes. Pure-culture experiments with an isolate that could utilize H(2)S and H(2) and that represented the dominant phylotype (70% of the PCR clones) showed that H(2)S and H(2) were used simultaneously, without evidence of induction or catabolite repression, and at relative rate differences comparable to those measured in ex situ field assays. Under in situ-relevant concentrations, growth of this isolate with H(2)S was better than that with H(2). The major conclusions drawn from this study are that phylogeny may not necessarily be reliable for predicting physiology and that H(2)S can dominate over H(2

  9. The relative importance of oceanic nutrient inputs for Bass Harbor Marsh Estuary at Acadia National Park, Maine

    Science.gov (United States)

    Huntington, Thomas G.; Culbertson, Charles W.; Fuller, Christopher; Glibert, Patricia; Sturtevant, Luke

    2014-01-01

    years. Oceanic inputs of nitrate and ammonium were an important source of inorganic nitrogen to the estuary in both years. In both years, the total seasonal inputs of ammonium to the estuary in flood tides were much larger than the inputs from watershed runoff or direct precipitation. In 2011, the total seasonal input of nitrate from flood tides to the estuary was more than twice as large the inputs from watershed runoff and precipitation, but in 2012, the inputs from flood tides were only marginally larger than the inputs from watershed runoff and precipitation. Turbidity was measured intermittently in 2012, and the pattern that emerged from the measurements indicated that the estuary was a source of particulate matter to the ocean rather than the ocean being a source to the estuary. From the nutrient budgets determined for the estuary it is evident that oceanic sources of nitrate and ammonium are an important part of the supply of nutrients that are contributing to the growth of macroalgae in the estuary. The relative importance of these oceanic nutrients compared with sources within the watershed typically increases as the summer progresses and runoff decreases. It is likely that rising sea levels, estimated by the National Oceanic and Atmospheric Administration to be 11 centimeters from 1950 through 2006 in nearby Bar Harbor, have resulted in an increase in oceanic inputs (tidal volume and nutrients derived from oceanic sources).

  10. The effect on the bones of condensed phosphate when used as food additives: Its Importance in Relation to Preventive Medicine.

    Science.gov (United States)

    Omoto, M; Imai, T; Seki, K; Nomura, R; Otahara, Y

    1997-10-01

    Based on the fact that chemical products such as binding agents are produced by mixing three kinds of phosphates with different ratios, we mixed metaphosphate, polyphosphate and pyrophosphate. Each was made to Na-phosphate, K-phosphate, and Ca-phosphate and each was mixed with commercial feeds so that the content of P would be approximately 0.1, 0.15, 0.3, 0.4, 0.6 and 1.0%. The prepared pellets were given to ICR, CF # 1 and AKR strains of mice at 29 days of age for 680 days and observations were made through this experimental period at different stages. The observations were also carried out on the mice administered with the experimental feeds for 1.5 months from 9 to 10.5 months of age. The observations were compared with those of the control group at all times. As a result, plasma 1 α, 25 (OH)(2) D(3) and P levels were always significantly higher in the phosphate administered groups relative to the control. Urine P and Fe increased while urine Ca decreased in the phosphate-treated groups.The effect of phosphates on the bones was studied taking soft X-ray pictures of hind legs and applying microdensitometry to them. Through these observations we recognized thinning of the cortex of bones, reduction of marrow trabecules and development of osteophyte. Histological observations disclosed that changes in knee joint tissues were apparent; that is, a decrease in or an irregular loss of the number of cells in superficial, intermediate, and radial strata of the joint cartilage, proliferation of subchondral bone, and the development of osteophytes were noted. As for muscles, diameters of musclar fibers became smaller; in particular, type II fibers showed greater shrinkage. Regarding kidneys, swelling and atrophy of glomerular capillaries, proliferation of mesangial cells, nephroselerosis, swelling, thinning, and loss of tubular epithelium, interstitial tissue inflammation, development of cylindruria, and deposition of calcium were observed. All these changes seem to be a

  11. No effect of a graded training program on the number of running-related injuries in novice runners

    NARCIS (Netherlands)

    Buist, Ida; Bredeweg, Steef W.; van Mechelen, Willem; Lemmink, Koen A. P. M.; Pepping, Gert-Jan; Diercks, Ron L.

    Background: Although running has positive effects on health and fitness, the incidence of a running-related injury (RRI) is high. Research on prevention of RRI is scarce; to date, no studies have involved novice runners. Hypothesis: A graded training program for novice runners will lead to a

  12. The total workload of male and female white collar workers as related to age, occupational level, and number of children.

    Science.gov (United States)

    Lundberg, U; Mårdberg, B; Frankenhaeuser, M

    1994-12-01

    A questionnaire assessing various aspects of paid as well as unpaid forms of productive activity was mailed to stratified samples of male and female white collar workers, approximately matched for educational and occupational level. Data from 501 men and 679 women employed full time revealed traditional gender differences in terms of main responsibility for household duties, child care etc. In keeping with this, women reported higher levels of work overload, stress and conflict than men, which increased significantly with the number of children at home. The various stress indices reached a peak between the ages of 35 and 39. Men reported more autonomy in their paid work whereas women reported more control at home. Men and women at the upper managerial levels reported more control over their total work situation and less conflict between demands.

  13. An inequality relating gauge group coupling constants and the number of generations in a string inspired model

    International Nuclear Information System (INIS)

    Nielsen, H.B.; Bennett, D.L.

    1987-12-01

    Using a model with a regularized (e.g. latticized) Kaluza-Klein space-time at the fundamental scale with Yang-Mills fields in the compactified dimensions, we examine the β-function for a dimensionless expression for the coupling constants g in D-dimensions. In going from the Planck scale of D > 4 down in energy to the scale where D goes from D > 4 to D = 4, it is argued that couplings are weakened by a factor roughly equal to the number of fundamental string regions that can be accommadated in the volume of the compactification space. Subsequently this factor is claimed to be greater than the number of generations by using an argument reminiscent of that often encountered in string model T.O.E. in which various quark and lepton generations are said to correspond to various zero modes of a Weyl operator in the compactifying space. Finally, it is argued that the inequality, which can be shown to be more saturated the larger the gauge group, is already near saturation for the group factors of the SMG. This fact leads to several conclusions: 1. there is not room for many more than 3 generations; 2. G.U.T. can be accommadated only at scales very close to the fundamental scale; 3. No new blossoms are expected to be found in the desert; 4. the compactifying space should not be 'larger than necessary'; 5. at the fundamental scale, couplings are expected to be close to (but not suspiciousely close to) β crit. . (orig./HSI)

  14. The importance of multidisciplinary teamwork and team climate for relational coordination among teams delivering care to older patients

    NARCIS (Netherlands)

    J.M. Hartgerink (Jacqueline); J.M. Cramm (Jane); T.J.E.M. Bakker (Ton); A.M. van Eijsden (A.); J.P. Mackenbach (Johan); A.P. Nieboer (Anna)

    2013-01-01

    textabstractAim: To identify predictors of relational coordination among professionals delivering care to older patients. Background: Relational coordination is known to enhance quality of care in hospitals. The underlying mechanisms, however, remain poorly understood. Design: This cross-sectional

  15. Using speeding detections and numbers of fatalities to estimate relative risk of a fatality for motorcyclists and car drivers.

    Science.gov (United States)

    Huggins, Richard

    2013-10-01

    Precise estimation of the relative risk of motorcyclists being involved in a fatal accident compared to car drivers is difficult. Simple estimates based on the proportions of licenced drivers or riders that are killed in a fatal accident are biased as they do not take into account the exposure to risk. However, exposure is difficult to quantify. Here we adapt the ideas behind the well known induced exposure methods and use available summary data on speeding detections and fatalities for motorcycle riders and car drivers to estimate the relative risk of a fatality for motorcyclists compared to car drivers under mild assumptions. The method is applied to data on motorcycle riders and car drivers in Victoria, Australia in 2010 and a small simulation study is conducted. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. The number of postsynaptic currents necessary to produce locomotor- related cyclic information in neurons in the neonatal rat spinal cord

    DEFF Research Database (Denmark)

    Raastad, Morten; Johnson, Bruce R.; Kiehn, Ole

    1996-01-01

    To understand better how synaptic signaling contributes to network activity, we analyzed the potential contribution of putative unitary postsynaptic currents (PSCs) to locomotor-related information received by spinal interneurons in neonatal rats. The average cyclic modulation of the whole-cell c......-5) of the synapses contributing to the cyclic information need to be active simultaneously. This suggests that individual presynaptic cells in a central locomotor network can have a powerful influence on other neurons....

  17. 31 CFR 593.510 - Transactions related to the importation of any round log or timber product originating in Liberia...

    Science.gov (United States)

    2010-07-01

    ... importation of any round log or timber product originating in Liberia authorized. 593.510 Section 593.510... importation of any round log or timber product originating in Liberia authorized. Except as otherwise... into the United States of any round log or timber product originating in Liberia are authorized. ...

  18. The Effectiveness of Clomiphene Citrate and Letrozole for Ovulation Induction Related to Endometrial Thickness and Number of Dominant Follicle

    Directory of Open Access Journals (Sweden)

    Budi Wiweko

    2016-09-01

    Full Text Available The aim of the study is to know the effectiveness of clomiphene citrate and letrozole for ovulationrelated to endometrial thickness and number of dominant follicle. Study design was cross sectional basedon medical records of women who underwent ovulation induction from January 2011-May 2015. A numberof 143 anovulation women were divided into clomiphene citrate 50mg, clomiphene citrate 100 mg, letrozole2.5mg and letrozole 5mg. Each group received the agent daily on 3rd-7th day of menstrual cycle. On 12thday of menstrual cycle, the transvaginal ultrasound was performed to measure endometrial thickness anddominant follicle number. From all subjects, 45 subjects (31.5% were in 50mg clomiphene citrate groups, 29subjects (20.3% in 100mg clomiphene citrate group, 23 subjects (16.1% in 2,5mg letrozole group, and 46subjects (32.2% in 5mg letrozole group. Subjects who received letrozole had thicker endometrium comparedto clomiphene citrate (p<0.05. Different doses were not associated with endometrial thickness betweensubjects who received either letrozole or clomiphene citrate. In addition, subjects receiving letrozole hadhigher proportion of having trilaminar endometrium morphology. We did not observe the difference in totalnumber of dominant follicle between groups. It is concluded that letrozole is more effective than clomiphenecitrate in terms of endometrial thickness but not for number of dominant follicles. Keywords: clomiphene citrate, letrozole, ovulation induction, endometrial thickness, dominant follicle   Efektivitas Induksi Ovulasi Klomifen Sitrat dan Letrozol dalam Hal KetebalanEndometrium dan Jumlah Folikel Dominan Abstrak Studi ini bertujuan untuk menilai efektivitas induksi ovulasi klomifen sitrat dan letrozol dalam halketebalan endometrium dan jumlah folikel dominan pada perempuan yang tidak berovulasi. Desain studiadalah potong lintang menggunakan rekam medik pasien yang menjalani induksi ovulasi pada bulan Januari2011-Mei 2015

  19. Analytic Hierarchy Process (AHP) for examining healthcare professionals' assessments of risk factors. The relative importance of risk factors for falls in community-dwelling older people.

    Science.gov (United States)

    Pecchia, L; Bath, P A; Pendleton, N; Bracale, M

    2011-01-01

    A gap exists between evidence-based medicine and clinical-practice. Every day, healthcare professionals (HCPs) combine empirical evidence and subjective experience in order to maximize the effectiveness of interventions. Consequently, it is important to understand how HCPs interpret the research evidence and apply it in everyday practice. We focused on the prevention of falls, a common cause of injury-related morbidity and mortality in later life, for which there is a wide range of known risk factors. To use the Analytic Hierarchy Process (AHP) to investigate the opinions of HCPs in prioritizing risk factors for preventing falls. We used the AHP to develop a hierarchy of risk factors for falls based on the knowledge and experience of experts. We submitted electronic questionnaires via the web, in order to reach a wider number of respondents. With a web service, we pooled the results and weighted the coherence and the experience of respondents. Overall, 232 respondents participated in the study: 32 in the technical pilot study, nine in the scientific pilot study and 191 respondents in the main study. We identified a hierarchy of 35 risk factors, organized in two categories and six sub-categories. The hierarchy of risk factors provides further insights into clinicians' perceptions of risk factors for falls. This hierarchy helps understand the relative importance that clinicians place on risk factors for falls in older people and why evidence-based guidelines are not always followed. This information may be helpful in improving intervention programs and in understanding how clinicians prioritize multiple risk factors in individual patients. The AHP method allows the opinions of HCPs to be investigated, giving appropriate weight to their coherence, background and experience.

  20. On-line Processing of German Number-marked Relative Clauses in the Visual-world Paradigm

    Directory of Open Access Journals (Sweden)

    Anne Adelt

    2014-04-01

    (3 Filler: Wo ist das Schwein mit dem Ballon? (Where is the pig with the balloon? All sentences are randomized and presented auditorily. Simultaneously, colored illustrations of animals performing an action are shown on a computer screen (see Figure 1. Participants have to identify via button press (left/right the target animal to which the question refers. During this task, eye movements are collected as an on-line measure of sentence processing. Off-line comprehension is measured in terms of accuracy of target identification. Ten IWAs with sentence comprehension deficits and 30 healthy controls are tested. Discussion Following Burchert et al. (2003, we expect the IWA’s off-line comprehension of SRCs and ORCs to be at chance level, while controls make hardly any errors. In the on-line data, the number of fixations to the target picture are supposed to increase only at the verb or shortly after the sentence offset, since disambiguation occurs sentence finally at the verb. Controls are expected to show faster or longer fixations to the target in SRCs compared to ORCs (Caplan et al., 2007. In line with Hanne, Sekerina, Vasishth, Burchert, and De Bleser (2011, IWA’s fixations to the target should not differ qualitatively from those of controls, at least for correct responses, but eye gaze patterns may be delayed. Data collection and analysis is still ongoing. Results will be ready by October and presented and discussed at the Academy of Aphasia conference.

  1. IMPLEMENTATION OF CORPORATE SOCIAL RESPONSIBILITY (CSR THROUGH WAQF RELATED TO LAW NUMBER 41 YEAR 2004 ON WAQF

    Directory of Open Access Journals (Sweden)

    Helza Nova Lita

    2015-04-01

    Full Text Available Objective - Corporate Social Responsibility (CSR is expected to continue to exist as an integral part of the management of a company. The existence of Law No. 41 Year 2004 on Waqf may be an appropriate alternative for the company to develop the concept of CSR through waqf management. Waqf is basically a form of philanthropy that is derived from Islamic law. It has its own characteristics that differentiate from other philanthropies. Characteristics of waqf  can provide a guarantee of legal protection for waqf objects that can be used to develop sustainable good deeds programs, instead of a normal charity program. The research discussess how the implementation of the concept of Corporate Social Responsibility through Waqf based on Law Number. 41 of 2004, and how the legal position of the company in the management of waqf.Methods – Analytical qualitative method on the legal aspect of waqf and theories of Islamic economics.Results - CSR within an Islamic framework includes a series of business activities in its various forms. The forms of CSR activities can be synergized through a planned management pattern, with separate funding sources.  Conclusions – The allocation of CSR through Waqf should be in accordance with the characteristics and conditions of the receiving society. Moreover, the role of  company in CSR management through waqf is either being a Wakif, Nazhir or partner of waqf institutions to improve productivity of waqf assets. Keywords : CSR, Waqf, Law

  2. Greek (Hesychian κόρος ‘great number of men’ and related words

    Directory of Open Access Journals (Sweden)

    Elwira Kaczyńska

    2007-12-01

    Full Text Available In this paper one Hesychian gloss is discussed from the historical-comparative point of view. It is suggested that the Ancient Greek appellative κόρος denoting ‘great number of men’ (πλῆθος ὰνθρώπων represents an archaic term (IE. *kóros ‘army, crowd; the people under arms’, which is attested also at the eastern periphery (especially in Iranian and Baltic and the western one (in Lusitanian, cf. Lusit. PN Coro-cuta, Coro-poti, Corobulti and so on. A variant Indo-European form *koryos appears as an appellative in Celtic, Germanic and Baltic, also as a first or second part of the ethnic and personal names (e.g. in Boeotian Greek, Celtic and Germanic. A primitive derivative *koryanos ‘army leader’ is firmly attested in Greek (see Gk. κοίρανος m. ‘ruler, leader, commander (in war or peace’, generally ‘lord, master’, also ‘king’ in the Boeotian dialect, North Germanic (cf. Odin’s by-name Herjann and perhaps in Lusitanian (see Lusit. PN Coriana.

  3. Study of the knowledge of Pediatricians and Senior Residents Relating to the Importance of Hearing Impairment and Deafness Screening Among Newborns in Isfahan city in 2012

    Directory of Open Access Journals (Sweden)

    Mehrdad Rogha

    2014-04-01

    Full Text Available Introduction: Newborn hearing screening leads to the early detection of hearing impairment. The aim of screening is to decrease or remove the effect of hearing impairment on development of speech and language by timely diagnosis and effective treatment. A number of risk factors lead to delayed start of decreased hearing ability including: 1. Congenital infection with cytomegalovirus  (CMV virus, 2. Meningitis, 3. Mumps, 4. Positive family history, 5. Head trauma, 6. Chemotherapy, 7. Syndrome pertaining to delayed start of decreased hearing. Unfortunately, lack of attention to early diagnosis of hearing impairment is becoming a general health problem. No research has yet been carried out relating to the knowledge of pediatricians on this issue, particularly the importance of hearing impairment and hearing screening. The aim of this study was to determine the attitude to newborn hearing screening among pediatricians.   Materials and Methods: This cross-sectional, descriptive-analytic study was conducted in Isfahan in 2012 among 300 pediatricians and final-year pediatric residents. An adjusted 22-question version of the Early Hearing Detection and Intervention (EHDI questionnaire was used to collect data. The validity and reliability of the EHDI questionnaire was previously demonstrated by Boys Town National Research Hospital and its Farsi translated version was validated by the EDC Center at the Isfahan University of Medical Sciences.   Results: In our study, 83% of pediatricians agreed on the importance of hearing impairment screening for all infants. However 65% were not aware of special needs for hearing-impaired patients.   Conclusion:  Newborn hearing impairment and deafness screening is important, irrespective of the costs, and lack of timely diagnosis results in both individual and social consequences. The majority of physicians use textbooks to gain information about hearing screening, but recognize that this is insufficient. Although

  4. Work-family conflict among Indonesian working couples: In relation to work and family role importance, support, and satisfaction

    NARCIS (Netherlands)

    Kuntari, I.S.R.

    2018-01-01

    Over the past two decades, the number of women entering the labour market has grown sharply in Indonesia. This led to a situation in which many couples experience work-family conflicts. Work-family conflicts can occur in two directions, work-to-family (WFC) and family-to-work (FWC) conflicts. WFC

  5. Imbalances in the German public health system - numbers of state-certified occupational physicians and relation to socioeconomic data.

    Science.gov (United States)

    Gyo, Christoph; Boll, Michael; Brüggmann, Dörthe; Klingelhöfer, Doris; Quarcoo, David; Groneberg, David A

    2016-01-01

    State-certified occupational physicians who work as civil servants in the Federal Republic of Germany are key players in the German Public Health system. They control i.e. the legal compliance in occupational health and participate in the occupational disease procedures. Despite the role model function of the German Public health system for many developing countries, this area of Public health is debated to have been hampered in the past years by a disregard concerning structural developments. Different databases were screened for occupational health benchmarks. Obtained data were compared to socioeconomic data and indices were calculated. The overall numbers of State-certified occupational physicians decreased in Germany between 1992 and 2012 from 136 to 86 (63 %). On the single state level, the ratios of State-certified occupational physicians per 1 Mio. working population ranged from 8 for the state of Saarland to 0.8 for the state of North Rhine Westphalia. A general difference was found for old versus new German states. Also, large differences were present for the ratios of State-certified occupational physicians per 10 6 employees towards public debt per capita (€) and the ratios of State-certified occupational physicians per Gross Domestic Product (GDP) in the 16 German states in 2012. In striking contrast to the WHO document on the Occupational safety and health (OSH) system that states in its executive summary that the human and institutional capacities of the German occupational health system are very strong in both quantity and quality, we here show extreme imbalances present at the single state levels that developed over the past 20 years. With a regard to the increasing complexity of the economic system a reversal of this trend should be demanded.

  6. Decreased physical effort, fatigue, and mental distress in patients with coronary artery disease : Importance of personality-related differences

    NARCIS (Netherlands)

    Bunevicius, A.; Brozaitiene, J.; Staniute, M.; Gelziniene, V.; Duoneliene, I.; Pop, V.J.M.; Bunevicius, R.; Denollet, J.

    2014-01-01

    Background Identification of cardio-toxic psychological symptoms in coronary artery disease (CAD) patients is important. Purpose We examined the association of negative affectivity (NA), social inhibition (SI), and their combination in the distressed (Type D) personality with functional status,

  7. The importance of team level tacit knowledge and related characteristics of high-performing health care teams.

    Science.gov (United States)

    Friedman, Leonard H; Bernell, Stephanie L

    2006-01-01

    Team level tacit knowledge is related to the collective knowledge of the team members. It is the shared experience that results in the ability to successfully anticipate the reactions of teammates in typical and nontypical situations. This study evaluates how tacit knowledge and related team characteristics influence the performance of cardiothoracic surgery teams.

  8. The importance of job autonomy, cognitive ability, and job-related skill for predicting role breadth and job performance.

    Science.gov (United States)

    Morgeson, Frederick P; Delaney-Klinger, Kelly; Hemingway, Monica A

    2005-03-01

    Role theory suggests and empirical research has found that there is considerable variation in how broadly individuals define their jobs. We investigated the theoretically meaningful yet infrequently studied relationships between incumbent job autonomy, cognitive ability, job-related skill, role breadth, and job performance. Using multiple data sources and multiple measurement occasions in a field setting, we found that job autonomy, cognitive ability, and job-related skill were positively related to role breadth, accounting for 23% of the variance in role breadth. In addition, role breadth was positively related to job performance and was found to mediate the relationship between job autonomy, cognitive ability, job-related skill, and job performance. These results add to our understanding of the factors that predict role breadth, as well as having implications for how job aspects and individual characteristics are translated into performance outcomes and the treatment of variability in incumbent reports of job tasks.

  9. Work-family conflict among Indonesian working couples: In relation to work and family role importance, support, and satisfaction

    OpenAIRE

    Kuntari, I.S.R.

    2018-01-01

    Over the past two decades, the number of women entering the labour market has grown sharply in Indonesia. This led to a situation in which many couples experience work-family conflicts. Work-family conflicts can occur in two directions, work-to-family (WFC) and family-to-work (FWC) conflicts. WFC and FWC decrease couples marital satisfaction and their job satisfaction. The negative impact of WFC decreases if couples receive social support from their supervisors, while spouse and extended fami...

  10. IMPORTANT NOTIFICATION

    CERN Multimedia

    HR Department

    2009-01-01

    Green plates, removals and importation of personal effects Please note that, as from 1 April 2009, formalities relating to K and CD special series French vehicle plates (green plates), removals and importation of personal effects into France and Switzerland will be dealt with by GS Department (Building 73/3-014, tel. 73683/74407). Importation and purchase of tax-free vehicles in Switzerland, as well as diplomatic privileges, will continue to be dealt with by the Installation Service of HR Department (Building 33/1-011, tel. 73962). HR and GS Departments

  11. A String Number-Line Lesson Sequence to Promote Students' Relative Thinking and Understanding of Scale, Key Elements of Proportional Reasoning

    Science.gov (United States)

    Hilton, Annette; Hilton, Geoff

    2018-01-01

    This article describes part of a study in which researchers designed lesson sequences based around using a string number line to help teachers support children's development of relative thinking and understanding of linear scale. In the first year of the study, eight teachers of Years 3-5 participated in four one-day professional development…

  12. The effect of relational constructs on customer referrals and number of services purchases from a multi-service provider: Does age of a relationship matter?

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); P.C. Verhoef (Peter); J.C. Hoekstra (Janny)

    2002-01-01

    textabstractThe authors examine the effect of relational constructs (e.g., satisfaction, trust, and affective and calculative commitment) on customer referrals and the number of services purchased, as well as the moderating effect of age of the relationship on these relationships. The research

  13. The importance of multidisciplinary teamwork and team climate for relational coordination among teams delivering care to older patients

    OpenAIRE

    Hartgerink, Jacqueline; Cramm, Jane; Bakker, Ton; Eijsden, A.; Mackenbach, Johan; Nieboer, Anna

    2013-01-01

    textabstractAim: To identify predictors of relational coordination among professionals delivering care to older patients. Background: Relational coordination is known to enhance quality of care in hospitals. The underlying mechanisms, however, remain poorly understood. Design: This cross-sectional study was part of a larger evaluation study examining the opportunity to prevent loss of function in older patients due to hospitalization in the Netherlands. Methods: This study was performed in sp...

  14. The importance of multidisciplinary teamwork and team climate for relational coordination among teams delivering care to older patients

    OpenAIRE

    J.M. Hartgerink; J.M. Cramm; T.J.E.M. Bakker; A.M. van Eijsden; J.P. Mackenbach; A.P. Nieboer

    2013-01-01

    Aim To identify predictors of relational coordination among professionals delivering care to older patients. Background Relational coordination is known to enhance quality of care in hospitals. The underlying mechanisms, however, remain poorly understood. Design This cross-sectional study was part of a larger evaluation study examining the opportunity to prevent loss of function in older patients due to hospitalization in the Netherlands. Methods This study was performed in spring 2010 among ...

  15. Lay Concepts of the Relative Importance of Different Influences on Health; Are There Major Socio-Demographic Variations?

    Science.gov (United States)

    Macintyre, Sally; McKay, Laura; Ellaway, Anne

    2006-01-01

    There is an extensive literature within anthropology, sociology and psychology about lay concepts of determinants of health and illness. Many of these studies have used single sex or social class samples, often in narrow age bands, and many are qualitative in approach. We asked respondents in a health survey to say how important (on a five-point…

  16. SU-C-BRC-05: Monte Carlo Calculations to Establish a Simple Relation of Backscatter Dose Enhancement Around High-Z Dental Alloy to Its Atomic Number

    Energy Technology Data Exchange (ETDEWEB)

    Utsunomiya, S; Kushima, N; Katsura, K; Tanabe, S; Hayakawa, T; Sakai, H; Yamada, T; Takahashi, H; Abe, E; Wada, S; Aoyama, H [Niigata University, Niigata (Japan)

    2016-06-15

    Purpose: To establish a simple relation of backscatter dose enhancement around a high-Z dental alloy in head and neck radiation therapy to its average atomic number based on Monte Carlo calculations. Methods: The PHITS Monte Carlo code was used to calculate dose enhancement, which is quantified by the backscatter dose factor (BSDF). The accuracy of the beam modeling with PHITS was verified by comparing with basic measured data namely PDDs and dose profiles. In the simulation, a high-Z alloy of 1 cm cube was embedded into a tough water phantom irradiated by a 6-MV (nominal) X-ray beam of 10 cm × 10 cm field size of Novalis TX (Brainlab). The ten different materials of high-Z alloys (Al, Ti, Cu, Ag, Au-Pd-Ag, I, Ba, W, Au, Pb) were considered. The accuracy of calculated BSDF was verified by comparing with measured data by Gafchromic EBT3 films placed at from 0 to 10 mm away from a high-Z alloy (Au-Pd-Ag). We derived an approximate equation to determine the relation of BSDF and range of backscatter to average atomic number of high-Z alloy. Results: The calculated BSDF showed excellent agreement with measured one by Gafchromic EBT3 films at from 0 to 10 mm away from the high-Z alloy. We found the simple linear relation of BSDF and range of backscatter to average atomic number of dental alloys. The latter relation was proven by the fact that energy spectrum of backscatter electrons strongly depend on average atomic number. Conclusion: We found a simple relation of backscatter dose enhancement around high-Z alloys to its average atomic number based on Monte Carlo calculations. This work provides a simple and useful method to estimate backscatter dose enhancement from dental alloys and corresponding optimal thickness of dental spacer to prevent mucositis effectively.

  17. Factors related to condom use behavior among club-working women in South Korea: importance of subjective norms and customer-related attitudes.

    Science.gov (United States)

    Jeong, Heon-Jae; Jo, Heui-Sug; Jung, Su-Mi; Lee, Ja-young

    2014-03-01

    The primary aim of this study was to understand factors associated with condom use behavior among club-working women and identify the most influential factors to be addressed in future health programs. A total of 158 club-working women were surveyed from 3 midsize cities in South Korea from July to September 2004. Survey questionnaires were developed based on the theory of planned behavior. A total of 7 distinct themes emerged: Health aspects, Customer related, Pleasure related, Finance related, Societal norm, Occupational norm, and Perceived control. The results indicated that the Customer-related theme, Societal norm, and Occupational norm were statistically significant factors affecting condom use. On the other hand, self-related factors such as health, pleasure, and finance are not significantly related to the condom use behavior of club-working women in South Korea, suggesting that the currently used knowledge-focused education programs may not be sufficient for this population.

  18. New Multilocus Variable-Number Tandem-Repeat Analysis (MLVA) Scheme for Fine-Scale Monitoring and Microevolution-Related Study of Ralstonia pseudosolanacearum Phylotype I Populations

    Science.gov (United States)

    Guinard, Jérémy; Latreille, Anne; Guérin, Fabien; Poussier, Stéphane

    2016-01-01

    ABSTRACT Bacterial wilt caused by the Ralstonia solanacearum species complex (RSSC) is considered one of the most harmful plant diseases in the world. Special attention should be paid to R. pseudosolanacearum phylotype I due to its large host range, its worldwide distribution, and its high evolutionary potential. So far, the molecular epidemiology and population genetics of this bacterium are poorly understood. Until now, the genetic structure of the RSSC has been analyzed on the worldwide and regional scales. Emerging questions regarding evolutionary forces in RSSC adaptation to hosts now require genetic markers that are able to monitor RSSC field populations. In this study, we aimed to evaluate the multilocus variable-number tandem-repeat analysis (MLVA) approach for its ability to discriminate genetically close phylotype I strains and for population genetics studies. We developed a new MLVA scheme (MLVA-7) allowing us to genotype 580 R. pseudosolanacearum phylotype I strains extracted from susceptible and resistant hosts and from different habitats (stem, soil, and rhizosphere). Based on specificity, polymorphism, and the amplification success rate, we selected seven fast-evolving variable-number tandem-repeat (VNTR) markers. The newly developed MLVA-7 scheme showed higher discriminatory power than the previously published MLVA-13 scheme when applied to collections sampled from the same location on different dates and to collections from different locations on very small scales. Our study provides a valuable tool for fine-scale monitoring and microevolution-related study of R. pseudosolanacearum phylotype I populations. IMPORTANCE Understanding the evolutionary dynamics of adaptation of plant pathogens to new hosts or ecological niches has become a key point for the development of innovative disease management strategies, including durable resistance. Whereas the molecular mechanisms underlying virulence or pathogenicity changes have been studied thoroughly, the

  19. Bathymetric variation in recruitment and relative importance of pre- and post-settlement processes in coral assemblages at Lyudao (Green Island, Taiwan.

    Directory of Open Access Journals (Sweden)

    Yoko Nozawa

    Full Text Available Studies on coral communities have typically been conducted in shallow waters (∼5 m. However, in the face of climate change, and as shallow coral communities become degraded, a greater understanding of deeper coral communities is needed as they become the main reef remnants, playing a central role in the future of coral reefs. To understand the dynamics of deeper coral assemblages, the recruitment and taxonomic composition of different life-stages at 5 and 15 m depths were compared at three locations in Lyudao, southeastern Taiwan in 2010. Coral recruits (5 cm, several years to decades old were examined using transect lines. Pocilloporid and poritid corals had similar and higher numbers of recruits at 5 m compared to 15 m, whereas acroporid recruits were more abundant at 15 m. The primary cause for the former may be larval behavior, such that they position themselves in shallow waters, while that for the latter may be the dominance of brooding acroporid species (Isopora spp. at 15 m. The taxonomic composition, especially between recruits and juveniles/adults, was more similar at 15 m than at 5 m. These results suggest a change in the relative importance of pre- and post-settlement processes in assemblage determinants with depth; coral assemblages in shallow habitats (more disturbed are more influenced by post-settlement processes (mortality events, while those in deeper habitats (more protected are more influenced by pre-settlement processes (larval supply.

  20. Aromatic plants play an important role in promoting soil biological activity related to nitrogen cycling in an orchard ecosystem.

    Science.gov (United States)

    Chen, Xinxin; Song, Beizhou; Yao, Yuncong; Wu, Hongying; Hu, Jinghui; Zhao, Lingling

    2014-02-15

    Aromatic plants can substantially improve the diversity and structure of arthropod communities, as well as reduce the number of herbivore pests and regulate the abundance of predators and parasitoids. However, it is not clear whether aromatic plants are also effective in improving soil quality by enhancing nutrient cycling. Here, field experiments are described involving intercropping with aromatic plants to investigate their effect on soil nitrogen (N) cycling in an orchard ecosystem. The results indicate that the soil organic nitrogen and available nitrogen contents increased significantly in soils intercropped with aromatic plants. Similarly, the activities of soil protease and urease increased, together with total microbial biomass involved in N cycling, including nitrifying bacteria, denitrifying bacteria and azotobacters, as well as the total numbers of bacteria and fungi. This suggests that aromatic plants improve soil N cycling and nutrient levels by enriching the soil in organic matter through the regulation of both the abundance and community structure of microorganisms, together with associated soil enzyme activity, in orchard ecosystems. Copyright © 2013 Elsevier B.V. All rights reserved.