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  1. National Center for Mathematics and Science - links to related sites

    Science.gov (United States)

    Mathematics and Science (NCISLA) HOME | WHAT WE DO | K-12 EDUCATION RESEARCH | PUBLICATIONS | TEACHER Modeling Middle School Mathematics National Association of Biology Teachers National Association for Mathematics National Science Teachers Assocation Show-Me Center Summit on Science TERC - Weaving Gender Equity

  2. Design and development of linked data from the National Map

    Science.gov (United States)

    Usery, E. Lynn; Varanka, Dalia E.

    2012-01-01

    The development of linked data on the World-Wide Web provides the opportunity for the U.S. Geological Survey (USGS) to supply its extensive volumes of geospatial data, information, and knowledge in a machine interpretable form and reach users and applications that heretofore have been unavailable. To pilot a process to take advantage of this opportunity, the USGS is developing an ontology for The National Map and converting selected data from nine research test areas to a Semantic Web format to support machine processing and linked data access. In a case study, the USGS has developed initial methods for legacy vector and raster formatted geometry, attributes, and spatial relationships to be accessed in a linked data environment maintaining the capability to generate graphic or image output from semantic queries. The description of an initial USGS approach to developing ontology, linked data, and initial query capability from The National Map databases is presented.

  3. Marketing activities and national development: is there a link ...

    African Journals Online (AJOL)

    The main objective of this study is to establish the link that exists between marketing and national development without losing sight of the intervening variables that might exist between them. The study suggested comparative advantage (CAD), resource-use efficiency (RUET), wealth creation (WECRE) as the possible ...

  4. Linking National and International Educational Assessments: NAEP and TIMSS

    Science.gov (United States)

    Rahman, Taslima

    2013-03-01

    In an increasingly global economy, comparisons of student achievement in the United States to student achievement in other countries are of interest to the nation. The National Center for Education Statistics (NCES) reports on mathematics and science achievement of 4th- and 8th-grade students for the all U.S. states and 60 countries. However, the reports are based on two separate assessments. Results for the U.S. states are based on the National Assessment of Educational Progress (NAEP) and results for the other countries are based on the Trends in International Mathematics and Science Study (TIMSS). Further, unlike NAEP, TIMSS does not have an on-going state component. Thus, U.S. states cannot compare performance of their students with those of the students in other countries. To enable such comparisons, NCES launched a NAEP-TIMSS Linking study where the goal is to project TIMSS mathematics and science scores for the students in the 50 states that participated in NAEP. This linking study targeted eighth-grade students. NAEP assessments of mathematics and science were conducted in winter 2011 (January-March) and TIMSS assessments of mathematics and science were conducted in spring 2011 (April-June). Three approaches-- statistical moderation, calibration, and projection--are applied in linking the two scales. In this presentation, discussion will focus on the study design and approaches applied. In addition, results will be shared if released to the public by the NCES before March 2013. Otherwise results of earlier linking study conducted by the American Institutes for Research in 2007 using the statistical moderation technique will be shared.

  5. International Relations: Understanding the Behavior of Nations.

    Science.gov (United States)

    Zack, David R.; And Others

    In today's world, no nation acts in isolation; the interdependence of nations makes international relations complex and ever-changing. This book is designed to help students understand why nations compete, why they cooperate, and why they sometimes go to war. Chapter 1 examines the behavior of nations and how national interest dictates the…

  6. Prospective Links between Social Anxiety and Adolescent Peer Relations

    Science.gov (United States)

    Tillfors, Maria; Persson, Stefan; Willen, Maria; Burk, William J.

    2012-01-01

    This study examines bi-directional links between social anxiety and multiple aspects of peer relations (peer acceptance, peer victimization, and relationship quality) in a longitudinal sample of 1528 adolescents assessed twice with one year between (754 females and 774 males; M = 14.7 years of age). Lower levels of peer acceptance predicted…

  7. Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project.

    Science.gov (United States)

    Cannon-Albright, Lisa A; Dintelman, Sue; Maness, Tim; Backus, Steve; Thomas, Alun; Meyer, Laurence J

    2013-07-01

    Creation of a genealogy of the United States and its ancestral populations is under way. When complete, this US genealogy will be record linked to the National Veteran's Health Administration medical data representing more than 8 million US veterans. Genealogical data are gathered from public sources, primarily the Internet. Record linking using data from relatives is accomplished to integrate multiple data sources and then to link genealogical data to the veteran's demographic data. This resource currently includes genealogy for more than 22 million individuals representing the Intermountain West and the East Coast. The demographic data for more than 40,000 veteran patients using Veterans Hospital Administration services in Utah and Massachusetts have already been record linked. The resource is only in its second year of creation and already represents the largest such combination of genealogy and medical data in the world. The data sources, the creation of the genealogy, record-linking methods and results, proposed genetic analyses, and future directions are discussed.

  8. NHRIC (National Health Related Items Code)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Health Related Items Code (NHRIC) is a system for identification and numbering of marketed device packages that is compatible with other numbering...

  9. Linking School and Work. Promising Practices from a National Demonstration.

    Science.gov (United States)

    Pressman, Harvey

    This book describes experimental demonstration programs in the United States on different ways to link school and work more meaningfully for disadvantaged teenagers. The programs are sponsored by Youthwork, Incorporated, a public-private partnership concerned with youth unemployment and the transition from school to work. The book provides…

  10. LINKS to NATIONAL WEATHER SERVICE MARINE FORECAST OFFICES

    Science.gov (United States)

    ; Organization Search Search Landlubber's forecast: "City, St" or zip code (Pan/Zoom for Marine) Search SERVICE MARINE FORECAST OFFICES (Click on the NWS Forecast Center/Office of interest to link to that Marine Forecasts in text form ) Coastal NWS Forecast Offices have regionally focused marine webpages

  11. Links between the Philippines and Spain: migration and bilateral relations

    Directory of Open Access Journals (Sweden)

    Rogelia Pe-Pua

    2005-01-01

    Full Text Available This paper analyses the implications which Spanish policy regarding foreign workers has on the living and working conditions of the Filipino community in Spain. The author pays special attention to bilateral relations between the Philippines and Spain in issues suchas Spanish investment in the Philippines, the trade balance between the two countries and labour relations. In conclusion the article considers the necessity of reaching a bilateral labour agreement which would be beneficial to both countries and which at the same time would improve the working conditions and the integration of Philippine nationals living in Spain.

  12. Big Five Traits Related to Short-Term Mating: From Personality to Promiscuity across 46 Nations

    Directory of Open Access Journals (Sweden)

    David P. Schmitt

    2008-04-01

    Full Text Available As part of the International Sexuality Description Project, 13,243 participants from 46 nations responded to self-report measures of personality and mating behavior. Several traits showed consistent links with short-term mating. Extraversion positively correlated with interest in short-term mating, unrestricted sociosexuality, having engaged in short-term mate poaching attempts, having succumbed to short-term poaching attempts of others, and lacking relationship exclusivity. Low levels of agreeableness and conscientiousness also related to short-term mating, especially with extra-pair mating. Neuroticism and openness were associated with short-term mating as well, but these links were less consistent across sex and nation. Nation-level links between personality and sexuality replicated within-region findings, such as the strong association between national extraversion and national sociosexuality. Discussion focuses on the origins of personality-sexuality links and their implications across nations.

  13. Public relations for a national observatory

    Science.gov (United States)

    Finley, David G.

    The National Radio Astronomy Observatory (NRAO) is a government-funded organization providing state-of-the art observational facilities to the astronomical community on a peer-reviewed basis. In this role, the NRAO must address three principal constituencies with its public-relations efforts. These are: the astronomical community; the funding and legislative bodies of the Federal Government; and the general public. To serve each of these constituencies, the Observatory has developed a set of public-relations initiatives supported by public-relations and outreach professionals as well as by management and scientific staff members. The techniques applied and the results achieved in each of these areas are described.

  14. Linking global scenarios to national assessments: Experiences from the Resources Planning Act (RPA) Assessment

    Science.gov (United States)

    Linda L. Langner; Peter J. Ince

    2012-01-01

    The Resources Planning Act (RPA) Assessment provides a nationally consistent analysis of the status and trends of the Nation's renewable forest resources. A global scenario approach was taken for the 2010 RPA Assessment to provide a shared world view of potential futures. The RPA Assessment scenarios were linked to the global scenarios and climate projections used...

  15. Linking national and global population agendas: case studies from eight developing countries.

    Science.gov (United States)

    Lee, K; Walt, G

    1995-06-01

    This comparative study of the determinants of family planning policy initiation and implementation focuses on four pairs of countries: Zambia/Zimbabwe, Algeria/Tunisia, Pakistan/Bangladesh, and Philippines/Thailand. The conclusion is drawn that global efforts had an influence on national policy makers and on putting family planning issues on the policy agenda. Global impacts were affected by national economic and social conditions and the broader political and economic relations with Western countries. The absolute level of economic development was found to be unrelated to the timing of initiation of family planning on national policy agendas. Stronger national family planning programs occurred in countries where policy makers linked economic development at whatever level with the need to limit population growth. Pakistan and Thailand in the 1960s illustrated this commitment to family planning programs, and Zambia and Algeria illustrated the lack of connection between development and population growth at the policy level and the lack of family planning on the policy agenda. Affiliation with the West during the 1960s meant early initiation of family planning in Pakistan/Bangladesh and Philippines/Thailand. Stronger commitment to program implementation occurred only in Thailand during the 1970s and Zimbabwe during the 1980s. Commitment lessened in the Philippines and Pakistan. Program implementation and national support of family planning were viewed as also dependent upon domestic factors, such as sufficient resources. Algeria/Tunisia and Zambia/Zimbabwe were countries that promoted family planning only after national political ideology shifted and anti-imperialist sentiments subsided. The impact of the international Cairo conference on these countries was minimal in terms of policy change. Most of the countries however desired greater support from donors. Even objections from the Vatican and internal domestic pressures were insufficient to prevent countries such as

  16. Inequality and adolescent cannabis use: A qualitative comparative analysis of the link at national level

    OpenAIRE

    Stevens, Alex

    2016-01-01

    Aim: This article explores the link between income inequality and adolescent cannabis use at the national level, in the context of other relevant social conditions, in developed countries. Methods and data: Fuzzy set qualitative comparative analysis is applied to two data sets that contain information on the national prevalence of past year cannabis use among 15 and 16 year olds, taken from the ESPAD and HBSC surveys, with supplementary data from the MtF and ASSAD surveys for the USA and Aust...

  17. Introducing technology learning for energy technologies in a national CGE model through soft links to global and national energy models

    International Nuclear Information System (INIS)

    Martinsen, Thomas

    2011-01-01

    This paper describes a method to model the influence by global policy scenarios, particularly spillover of technology learning, on the energy service demand of the non-energy sectors of the national economy. It is exemplified by Norway. Spillover is obtained from the technology-rich global Energy Technology Perspective model operated by the International Energy Agency. It is provided to a national hybrid model where a national bottom-up Markal model carries forward spillover into a national top-down CGE model at a disaggregated demand category level. Spillover of technology learning from the global energy technology market will reduce national generation costs of energy carriers. This may in turn increase demand in the non-energy sectors of the economy because of the rebound effect. The influence of spillover on the Norwegian economy is most pronounced for the production level of industrial chemicals and for the demand for electricity for residential energy services. The influence is modest, however, because all existing electricity generating capacity is hydroelectric and thus compatible with the low emission policy scenario. In countries where most of the existing generating capacity must be replaced by nascent energy technologies or carbon captured and storage the influence on demand is expected to be more significant. - Highlights: → Spillover of global technology learning may be forwarded into a macroeconomic model. → The national electricity price differs significantly between the different global scenarios. → Soft-linking global and national models facilitate transparency in the technology learning effect chain.

  18. A Link between Mothers' Disciplinary Strategies and Children's Relational Aggression

    Science.gov (United States)

    Sandstrom, Marlene J.

    2007-01-01

    This study examines the association between maternal disciplinary strategies and children's level of relational aggression, and then compares these associations with those found with overt aggression. Eighty-two 4th graders (aged 9-11 years) completed peer nomination measures of relational and overt aggression, and their mothers completed a…

  19. Emotional Intelligence and Its Link to Public Relations Education

    Science.gov (United States)

    Howard, Timothy Lent

    2011-01-01

    The purpose of this study is to examine the ethics chapters in five introduction-to-public relations textbooks and the codes of ethics of four major public relations associations contained within those chapters to determine the prevalence of language that either uses the same terms Daniel Goleman employs for his 25 competencies of emotional…

  20. Tuvan-Mongolian relations and links under the People’s Republic of Tuva

    Directory of Open Access Journals (Sweden)

    Lubov K. Hertek

    2016-09-01

    Full Text Available The article examines the links and relations between Tuva and Mongolia during the two decades of People’s Republic of Tuva (1921-1944. Although some aspects of these relations have been studied by a number of Russian, Mongolian and Chinese scholars, they have so far failed to outline their general tendencies. In this article, we aim to study the Tuvan-Mongolian relations in the PRT period in the light of new archival materials, which will help us trace the main stages of their development and characterize the specific features of each stage. The first stage (1921-1925 opens with the establishment of Tuvan statehood and its non-recognition by Mongolia. Tuvan lamas and noyons retained their links to the highest-profile Mongolian clergy and the rulers of Mongolian aimags in the borderlands. The second stage (1926–1929 begins with the changes in leadership of both states, which led to PRT being officially recognized by the Mongolian People’s Republic. The recognition was followed by signing a Treaty of Friendship between the two states and the restoration of cultural links, given that traditional culture and the Mongolian written language still prevailed in Tuva. We have reconstructed a full list of Tuvan diplomatic envoys in Mongolia and Mongolian envoys in Tuva. The third stage (1930–1944 was marked by the victory of the political left in both Tuva and Mongolia. The new leaders of both states had been educated in Moscow, in Communist University of the Toilers of the East. This helped establish what was deemed ‘truly revolutionary mutual relations’ and build up an interparty network. Indirectly, it also helped enhance economic, trade and cultural links. Our study was based, among other sources, on archival documents from the State Archive of the Republic of Tuva, the research archive of Tuva Institute for Humanities and Applied Socioeconomic Studies, and some published sources from the Mongolian Ministry of Foreign Affairs’ archive

  1. Possible Links among Mirror Neurons and Genes Related to Autism

    OpenAIRE

    MOCHIZUKI, Mai; 望月,麻衣

    2016-01-01

    Autism includes many neurodevelopmental disorders and defi cits in communication. Althoughresearchers have considered various origins, the onset mechanism is still not clear. The aim ofthis article is to provide some clues for interaction of autism with mirror neuronal and geneticfactors. First, the impact of neural brain cells considered to infl uence autism will be discussedwith reference to mirror neurons. Then, the discussion will move to genes related to autism.Consequently, it is argued...

  2. LINK BETWEEN SKELETAL RELATIONS AND ROOT RESORPTION IN ORTHODONTIC PATIENTS

    Directory of Open Access Journals (Sweden)

    Cristina Teodora Preoteasa

    2011-09-01

    Full Text Available External root resorption is one of the possible complications of the orthodontic treatment, severe cases presenting a higher frequency. The aim of the present study was to test the existence of a relation between the severity of root resorption and the sagittal or vertical skeletal relations. A cross-sectional study was conducted on a group of 55 patients with fixed orthodontic devices, applied bimaxillarily for at least 6 months. The sample presented mostly mild or moderate apical root resorption, with an average value of 1.31 mm (standard deviation 0.60. Patients with abnormal sagittal skeletal relations presented a more severe root resorption compared to those with a normal pattern. The tendency towards more severe external root resorption was also noticed in cases with mandibular clockwise rotation and hiperdivergent facial pattern. A good knowledge on the variables associated to severe root resorption is essential for the identification of the high risk patients, as well as for the selection of the best suited treatment alternative in terms of low probability of root resorption occurrence.

  3. Cell protein cross-linking by erbstatin and related compounds | Center for Cancer Research

    Science.gov (United States)

    The scheme depicts a possible mechanism of cross-linking by erbstatin and related analogues. A mechanism of action is proposed which involves initial oxidation to reactive quinone intermediates that subsequently cross-link protein nucleophiles via multiple 1,4-Michael-type additions. Similar alkylation of protein by protein-tyrosine kinase inhibitors, such as herbimycin A, has

  4. National outbreak of Salmonella Give linked to a local food manufacturer in Malta, October 2016.

    Science.gov (United States)

    Donachie, A; Melillo, T; Bubba, L; Hartman, H; Borg, M-L

    2018-06-26

    Salmonella Give is a rare serotype across Europe. In October 2016, a national outbreak of S. Give occurred in Malta. We describe the epidemiological, environmental, microbiological and veterinary investigations. Whole-genome sequencing (WGS) was performed on human, food, environmental and veterinary isolates. Thirty-six human cases were reported between October and November 2016, 10 (28%) of whom required hospitalisation. Twenty-six (72%) cases were linked to four restaurants. S. Give was isolated from ready-to-eat antipasti served by three restaurants which were all supplied by the same local food manufacturer. Food-trace-back investigations identified S. Give in packaged bean dips, ham, pork and an asymptomatic food handler at the manufacturer; inspections found inadequate separation between raw and ready-to-eat food during processing. WGS indicated two genetically distinguishable strains of S. Give with two distinct clusters identified; one cluster linked to the local food manufacturer and a second linked to veterinary samples. Epidemiological, environmental and WGS evidence pointed towards cross-contamination of raw and ready-to-eat foods at the local manufacturer as the likely source of one cluster. Severity of illness indicates a high virulence of this specific serotype. To prevent future cases and outbreaks, adherence to food safety practices at manufacturing level need to be reinforced.

  5. National practices in relation to severe accidents

    International Nuclear Information System (INIS)

    Soda, Kunihisa

    1989-01-01

    After the accidents at Three Mile Island and Chernobyl, many studies have been carried out on severe accidents by various organizations including IAEA and OECD/CSNI. In the present article, measures taken in different countries against severe accidents are outlined based on the results of these studies. In Sweden, policies for the management of a severe accident and reduction in the release of radioactive materials were established based on reports issued by the Atomic Energy Committee, which was set up after the Three Mile Island accident. The current policies require that filter vents be provided where necessary. France, following Sweden, adopted the use of filter vents. Operation procedures to be followed in the event of a severe accident have been established in the nation. The measures against severe accidents adopted in West Germany mainly focus on the weakening of the effects of accidents, and are not covered by the design standards. The use of filter vents are also required in Finland and Switzerland. In the U.S., a program for individual plant examination will be implemented over the three-year period beginning in 1989. Studies on measures against severe accidents seem to be performed also in the Soviet Union. (N.K.)

  6. Managing coopetition through horizontal supply chain relations : Linking dyadic and network levels of analysis

    NARCIS (Netherlands)

    Wilhelm, Miriam M.

    2011-01-01

    A growing research stream has expanded the level of analysis beyond single buyer-supplier relations to the network, including supplier-supplier relations. These supplier-supplier relations may constitute a missing link between the traditional analysis of the dyadic and the network level of analysis

  7. Managing coopetition through horizontal supply chain relations : Linking dyadic and network levels of analysis

    NARCIS (Netherlands)

    Wilhelm, Miriam M.

    A growing research stream has expanded the level of analysis beyond single buyer-supplier relations to the network, including supplier-supplier relations. These supplier-supplier relations may constitute a missing link between the traditional analysis of the dyadic and the network level of analysis

  8. Mach-Zehnder Fiber-Optic Links for Reaction History Measurements at the National Ignition Facility

    International Nuclear Information System (INIS)

    Miller, E. Kirk; Herrmann, H.W.; Stoeffl, W.; Horsfield, C.J.

    2009-01-01

    We present the details of the analog fiber-optic data link that will be used in the chamber-mounted Gamma Reaction History (GRH) diagnostic at the National Ignition Facility (NIF) located at the Lawrence Livermore Laboratory in Livermore, California. The system is based on Mach-Zehnder (MZ) modulators integrated into the diagnostic, with the source lasers and bias control electronics located remotely to protect the active electronics. A complete recording system for a single GRH channel comprises two MZ modulators, with the fiber signals split onto four channels on a single digitizer. By carefully selecting the attenuation, the photoreceiver, and the digitizer settings, the dynamic range achievable is greater than 1000:1 at the full system bandwidth of greater than 10 GHz. The system is designed to minimize electrical reflections and mitigate the effects of transient radiation darkening on the fibers.

  9. Explaining Differences in Subjective Well-Being Across 33 Nations Using Multilevel Models: Universal Personality, Cultural Relativity, and National Income.

    Science.gov (United States)

    Cheng, Cecilia; Cheung, Mike W-L; Montasem, Alex

    2016-02-01

    This multinational study simultaneously tested three prominent hypotheses--universal disposition, cultural relativity, and livability--that explained differences in subjective well-being across nations. We performed multilevel structural equation modeling to examine the hypothesized relationships at both individual and cultural levels in 33 nations. Participants were 6,753 university students (2,215 men; 4,403 women; 135 did not specify), and the average age of the entire sample was 20.97 years (SD = 2.39). Both individual- and cultural-level analyses supported the universal disposition and cultural relativity hypotheses by revealing significant associations of subjective well-being with Extraversion, Neuroticism, and independent self-construal. In addition, interdependent self-construal was positively related to life satisfaction at the individual level only, whereas aggregated negative affect was positively linked with aggregate levels of Extraversion and interdependent self-construal at the cultural level only. Consistent with the livability hypothesis, gross national income (GNI) was related to aggregate levels of negative affect and life satisfaction. There was also a quadratic relationship between GNI and aggregated positive affect. Our findings reveal that universal disposition, cultural self-construal, and national income can elucidate differences in subjective well-being, but the multilevel analyses advance the literature by yielding new findings that cannot be identified in studies using individual-level analyses alone. © 2014 Wiley Periodicals, Inc.

  10. Scotland's Water Map: Understanding water sector links to support decision making for the Hydro Nation Agenda

    Science.gov (United States)

    Falconer, Ruth E.; Gilmour, Daniel; Duffy, Alison; Isaacs, John; Stojanovic, Vladeta; O'Keeffe, Juliette; Blackwood, David

    2015-04-01

    The value of Scotland's water and sewerage market is projected to grow to £1.24bn by 2016/17. Developing future opportunities must take place alongside maintaining current service provision; however the demand on water and waste water services is constantly evolving. An integrated approach to water management requires an understanding of complex interactions that exist between key actors in the sector to allow water management strategies to exploit inter-sectorial links. Successful integrated analysis of the water sector in Scotland will support management activities key to responding to the Hydro Nation themes of 1) Governance and international development 2) Environmental protection 3) Economic opportunities 4) Research development. In order to deliver on these objectives an approach is required to capture and communicate the scope and scale of the water sector and its interconnectedness. The methodology required to determine scope, scale and interconnectedness of water sector involved the identification and application of an appropriate range of techniques from the Information and Knowledge Management disciplines combined with the Information Visualisation field. Scope and scale of the water sector was identified by a desk based study and this data was visualized using a geographic map. Sector interconnectedness was determined by interviewing key actors. The interviews identified the stakeholders associated with information flows, and the purpose of the information transfer through Reporting/Managing (R/M), Influence and Information sharing (I) or Control (C) activities. Primary information flows were also scored with respect to importance against the 4 key Hydro Nation agenda themes. Many organisations were identified who interact within Scotland's water sector including the Scottish Government and Ministers, the Regulators (WICS, DWQR, SEPA), Scottish Water (core and non-core functions), plus many other stakeholders ranging from research institutions to

  11. National Database for Clinical Trials Related to Mental Illness (NDCT)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Database for Clinical Trials Related to Mental Illness (NDCT) is an extensible informatics platform for relevant data at all levels of biological and...

  12. Interactive Links between Relational Aggression, Theory of Mind, and Moral Disengagement among Early Adolescents

    Science.gov (United States)

    Kokkinos, Constantinos M.; Voulgaridou, Ioanna; Mandrali, Marianna; Parousidou, Chrysoula

    2016-01-01

    The aim of this study was to investigate possible interactive links between theory of mind (ToM), moral disengagement and relational aggression, using a moderated mediation analysis, with gender as a moderator, in a sample of 120 Greek preadolescents. Results indicated that relational aggression was significantly positively associated with moral…

  13. Bauhinia forficata Link authenticity using flavonoids profile: relation with their biological properties.

    Science.gov (United States)

    Ferreres, Federico; Gil-Izquierdo, Angel; Vinholes, Juliana; Silva, Sara T; Valentão, Patrícia; Andrade, Paula B

    2012-09-15

    HPLC-DAD-ESI/MS(n) was used to ascertain the authenticity of two certified and two commercial Bauhinia forficata Link samples. Different flavonoids profiles were obtained, involving 39 compounds. Just kaempferol-3-O-(2-rhamnosyl)rutinoside was found in all analysed samples. Five compounds were common to the certified samples of B. forficata Link and B. forficata Link subsp. pruinosa (Vogel) Fortunato & Wunderlin, being kaempferol derivatives the most representative ones. The phenolic composition of B. forficata Link subsp. pruinosa (Vogel) Fortunato & Wunderlin is described herein for the first time, accounting for eight compounds, while 10 new compounds were identified in B. forficata Link. Commercial B. forficata Link showed higher contents of quercetin derivatives, in addition to the presence of myricetin derivatives and flavonoids-(galloyl)glycosides, for which the MS fragmentation pattern is reported for the first time. B. forficata Link and the two commercial samples were able to inhibit α-glucosidase, with EC(50) values lower than that found for acarbose. Mild effects on cholinesterases were observed with the certified samples, while commercial ones were more effective. The same behaviour was observed concerning the scavenging of DPPH, nitric oxide and superoxide radicals. The presence of high contents of quercetin derivatives in commercial samples seems to directly influence their biological properties. The differences between phenolic profiles and their relation with the authenticity of commercial samples are discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation.

    Directory of Open Access Journals (Sweden)

    Katherine I Morley

    Full Text Available National electronic health records (EHR are increasingly used for research but identifying disease cases is challenging due to differences in information captured between sources (e.g. primary and secondary care. Our objective was to provide a transparent, reproducible model for integrating these data using atrial fibrillation (AF, a chronic condition diagnosed and managed in multiple ways in different healthcare settings, as a case study.Potentially relevant codes for AF screening, diagnosis, and management were identified in four coding systems: Read (primary care diagnoses and procedures, British National Formulary (BNF; primary care prescriptions, ICD-10 (secondary care diagnoses and OPCS-4 (secondary care procedures. From these we developed a phenotype algorithm via expert review and analysis of linked EHR data from 1998 to 2010 for a cohort of 2.14 million UK patients aged ≥ 30 years. The cohort was also used to evaluate the phenotype by examining associations between incident AF and known risk factors.The phenotype algorithm incorporated 286 codes: 201 Read, 63 BNF, 18 ICD-10, and four OPCS-4. Incident AF diagnoses were recorded for 72,793 patients, but only 39.6% (N = 28,795 were recorded in primary care and secondary care. An additional 7,468 potential cases were inferred from data on treatment and pre-existing conditions. The proportion of cases identified from each source differed by diagnosis age; inferred diagnoses contributed a greater proportion of younger cases (≤ 60 years, while older patients (≥ 80 years were mainly diagnosed in SC. Associations of risk factors (hypertension, myocardial infarction, heart failure with incident AF defined using different EHR sources were comparable in magnitude to those from traditional consented cohorts.A single EHR source is not sufficient to identify all patients, nor will it provide a representative sample. Combining multiple data sources and integrating information on treatment and

  15. Water resources planning in a strategic context: Linking the water sector to the national economy

    Science.gov (United States)

    Rogers, Peter; Hurst, Christopher; Harshadeep, Nagaraja

    1993-07-01

    In many parts of the developing world investment in water resources takes a large proportion of the available public investment funds. As the conflicts for funds between the water and other sectors become more severe, the traditional ways of analyzing and planning water investments has to move away from project-by-project (or even a river basin-by-river basin) approaches to include the relationships of water investments to other sectors and to overall national development policies. Current approaches to water resources investments are too narrow. There is a need for ways to expand the strategic thinking of water sector managers. This paper develops a water resources planning methodology with the primary objective of giving insights into the linking of water sector investments and macroeconomic policies. The model optimizes the present value of investments for water resources development, while embedding a macroeconomic model into the framework to allow for an examination of the interactions between water investments, the growth in the agricultural sector, and the performance of the overall economy. A case study of Bangladesh is presented which shows how strategic thinking could lead to widely differing implications for water investments than would conventional water resources systems planning models.

  16. National Take-Back Initiative

    Science.gov (United States)

    ... Disposal Information Drug and Chemical Information E-commerce Initiatives Federal Agencies & Related Links Federal Register Notices National ... Disposal Information Drug and Chemical Information E-commerce Initiatives Federal Agencies & Related Links Federal Register Notices National ...

  17. Testing links between childhood positive peer relations and externalizing outcomes through a randomized controlled intervention study

    NARCIS (Netherlands)

    Witvliet, M.; van Lier, P.A.C.; Cuijpers, P.; Koot, H.M.

    2009-01-01

    In this study, the authors used a randomized controlled trial to explore the link between having positive peer relations and externalizing outcomes in 758 children followed from kindergarten to the end of 2nd grade. Children were randomly assigned to the Good Behavior Game (GBG), a universal

  18. Longitudinal Links between Spanking and Children's Externalizing Behaviors in a National Sample of White, Black, Hispanic, and Asian American Families

    Science.gov (United States)

    Gershoff, Elizabeth T.; Lansford, Jennifer E.; Sexton, Holly R.; Davis-Kean, Pamela; Sameroff, Arnold J.

    2012-01-01

    This study examined whether the longitudinal links between mothers' use of spanking and children's externalizing behaviors are moderated by family race/ethnicity, as would be predicted by cultural normativeness theory, once mean differences in frequency of use are controlled. A nationally representative sample of White, Black, Hispanic, and Asian…

  19. CONSTITUTIONAL ORDER, NATIONAL DEFENSE AND CI IL MILITARY RELATIONS

    Directory of Open Access Journals (Sweden)

    Miguel Navarro Meza

    2017-12-01

    Full Text Available Since the beginning of its independent life, the several constitutions of Chile have included concepts related ith defence, sovereignty and national security. At the same time, those constitutional texts have recognized the existence of the armed organizations of the State, under the generic name of Public Force and have addressed their relation ith the political authorities, both ith the Executive and Congress. his has not been a permanent process. n the contrary, it has suffered upheavals and bac steps, but the general path has been clear and progressive. For one thing, the norms related to the armed forces have been, in comparative terms, more thoroughly developed than those referring to defence, sovereignty and national security. hen, from the 1833 Constitution, the basic elements of the relations bet een the political authorities and the military have evolved so as to ensure a genuine civilian control over the military, in line ith contemporary theories of civilDmilitary relations. he ay in hich the 1980 Constitution addresses national security and defence and its provisions that recognize the existence of the armed forces, their missions and roles and that regulate the ay in hich they relate to the political authorities, are the result of a progressive development starting ith the Provisional Constitution of 1811 up to present times, and they are completely in line ith current theories about civilDmilitary relations in democracy.

  20. Tackling Work Related Stress in a National Health Service Trust

    Science.gov (United States)

    Vick, Donna; Whyatt, Hilary

    2004-01-01

    The challenge of tackling the problem of coping with work related stress in a National Health Service (NHS) Trust was undertaken. Ideas were developed within the context of two different action learning sets and led to actions resulting in a large therapy Taster Session event and the establishment of a centre offering alternative therapies and…

  1. Relative tracking control of constellation satellites considering inter-satellite link

    Science.gov (United States)

    Fakoor, M.; Amozegary, F.; Bakhtiari, M.; Daneshjou, K.

    2017-11-01

    In this article, two main issues related to the large-scale relative motion of satellites in the constellation are investigated to establish the Inter Satellite Link (ISL) which means the dynamic and control problems. In the section related to dynamic problems, a detailed and effective analytical solution is initially provided for the problem of satellite relative motion considering perturbations. The direct geometric method utilizing spherical coordinates is employed to achieve this solution. The evaluation of simulation shows that the solution obtained from the geometric method calculates the relative motion of the satellite with high accuracy. Thus, the proposed analytical solution will be applicable and effective. In the section related to control problems, the relative tracking control system between two satellites will be designed in order to establish a communication link between the satellites utilizing analytical solution for relative motion of satellites with respect to the reference trajectory. Sliding mode control approach is employed to develop the relative tracking control system for body to body and payload to payload tracking control. Efficiency of sliding mode control approach is compared with PID and LQR controllers. Two types of payload to payload tracking control considering with and without payload degree of freedom are designed and suitable one for practical ISL applications is introduced. Also, Fuzzy controller is utilized to eliminate the control input in the sliding mode controller.

  2. Linking social capital and mortality in the elderly: a Swedish national cohort study.

    Science.gov (United States)

    Sundquist, Kristina; Hamano, Tsuyoshi; Li, Xinjun; Kawakami, Naomi; Shiwaku, Kuninori; Sundquist, Jan

    2014-07-01

    Our objective was to examine the association between neighborhood linking social capital (a concept describing the amount of trust between individuals and societal institutions) and all-cause and cause-specific mortality in the elderly. The entire Swedish population aged 65+, a total of 1,517,336 men and women, was followed from 1 January 2002 until death, emigration, or the end of the study on 31 December 2010. Small geographic units were used to define neighborhoods. The definition of linking social capital was based on neighborhood voting participation rates, categorized into three groups. Multilevel logistic regression was used to estimate odds ratios (ORs) and between-neighborhood variance in three different models. The results showed an overall association between linking social capital and all-cause mortality. The significant OR of 1.53 in the group with low linking social capital decreased, but remained significant (OR=1.27), after accounting for age, sex, family income, marital status, country of birth, education level, and region of residence. There were also significant associations between linking social capital and cause-specific mortality in coronary heart disease, psychiatric disorders, cancer, stroke, chronic lower respiratory diseases, type 2 diabetes, and suicide. There are associations between low linking social capital and mortality from chronic disorders and suicide in the elderly population. Community support for elderly people living in neighborhoods with low levels of linking social capital may need to be strengthened. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Inter-firm relations in SME clusters and the link to marketing performance

    OpenAIRE

    Lamprinopoulou, C.; Tregear, A.

    2011-01-01

    Purpose – Networks are increasingly recognised as being important to successful marketing amongst small and medium-sized enterprises (SMEs). Thepurpose of this study is to investigate the structure and content of network relations amongst SME clusters, and explore the link to marketing performance.Design/methodology/approach – Following a review of the literature on SME networks and marketing performance, case study analysis isperformed on four SME clusters in the Greek agrifood sector.Findin...

  4. Investigation of China’s national public relations strategy under globalization : the hotspots around the national media

    OpenAIRE

    雷, 紫雯

    2014-01-01

    This study investigates on China’s national public relations strategy under the globalization by analyzing the national media. In recent years, in order to improve the global public opinion environment, and to improve its national public relations capabilities that match its economic power status, China has actively strengthened its national public relations strategies, including making the national “media go out”, and building world-class media. By researching on the localization of Chinese ...

  5. Dwelling on it may make it worse: the links between relational victimization, relational aggression, rumination, and depressive symptoms in adolescents.

    Science.gov (United States)

    Mathieson, Lindsay C; Klimes-Dougan, Bonnie; Crick, Nicki R

    2014-08-01

    Although there is considerable evidence that relational victimization is associated with depressive symptoms in youth, our understanding about the mechanisms by which victimization and depressive symptoms are linked is limited. The current study explored ruminating about victimization experiences as a potential mechanism that might contribute to an understanding of the association between relational victimization and depressive symptoms. We also tested the specificity of the proposed models by controlling for and testing parallel models of a highly related behavior: relational aggression. A sample of 499 adolescents from sixth through eighth grades participated. Teacher reports were used to assess relational victimization and relational aggression. Self-reports were used to assess depressive symptoms and rumination. The results showed that rumination partially mediated the association between relational victimization and depressive symptoms. No moderation effect was found. In contrast, rumination moderated the association between relational aggression and depressive symptoms. Specifically, relational aggression was associated with depressive symptoms for those adolescents who were also ruminators. Thus, ruminating about victimization experiences appears to be an important mechanism that functions differently for relational aggression and relational victimization in conferring risk for depressive symptoms. The findings offer important practical implications for those working with adolescents and also lay the groundwork for future research.

  6. Reliving emotional personal memories: affective biases linked to personality and sex-related differences.

    Science.gov (United States)

    Denkova, Ekaterina; Dolcos, Sanda; Dolcos, Florin

    2012-06-01

    Although available evidence suggests that the emotional valence and recollective properties of autobiographical memories (AMs) may be influenced by personality- and sex-related differences, overall these relationships remain poorly understood. The present study investigated these issues by comparing the effect of general personality traits (extraversion and neuroticism) and specific traits linked to emotion regulation (ER) strategies (reappraisal and suppression) on the retrieval of emotional AMs and on the associated postretrieval emotional states, in men and women. First, extraversion predicted recollection of positive AMs in both men and women, whereas neuroticism predicted the proportion of negative AMs in men and the frequency of rehearsing negative AMs in women. Second, reappraisal predicted positive AMs in men, and suppression predicted negative AMs in women. Third, while reliving of positive memories had an overall indirect effect on postretrieval positive mood through extraversion, reliving of negative AMs had a direct effect on postretrieval negative mood, which was linked to inefficient engagement of suppression in women. Our findings suggest that personality traits associated with positive affect predict recollection of positive AMs and maintenance of a positive mood, whereas personality traits associated with negative affect, along with differential engagement of habitual ER strategies in men and women, predict sex-related differences in the recollection and experiencing of negative AMs. These findings provide insight into the factors that influence affective biases in reliving AMs, and into their possible link to sex-related differences in the susceptibility to affective disorders.

  7. Hybrid Multidimensional Relational and Link Analytical Knowledge Discovery for Law Enforcement

    Energy Technology Data Exchange (ETDEWEB)

    Joslyn, Cliff A.; Gillen, David S.; Burke, John S.; Critchlow, Terence J.; Damante, Matt; Fernandes, Robert

    2008-08-01

    The challenges facing the Department of Homeland Security (DHS) require not only multi-dimensional, but also multi-scale data analysis. In particular, the ability to seamlessly move from summary information, such as trends, into detailed analysis of individual entities, while critical for law enforcement, typically requires manually transferring information among multiple tools. Such time-consuming and error prone processes significantly hamper the analysts' ability to quickly explore data and identify threats. As part of a DHS Science and Technology effort, we have been developing and deploying for Immigration and Customs Enforcement the CubeLink system integrating information between relational data cubes and link analytical semantic graphs. In this paper we describe CubeLink in terms of the underlying components, their integration, and the formal mapping from multidimensional data analysis into link analysis. In so doing, we provide a formal basis for one particular form of automatic schema-ontology mapping from OLAP data cubes to semantic graphs databases, and point the way towards future ``intelligent'' OLAP data cubes equipped with meta-data about their dimensional typing.

  8. Multiple Brain Markers are Linked to Age-Related Variation in Cognition

    Science.gov (United States)

    Hedden, Trey; Schultz, Aaron P.; Rieckmann, Anna; Mormino, Elizabeth C.; Johnson, Keith A.; Sperling, Reisa A.; Buckner, Randy L.

    2016-01-01

    Age-related alterations in brain structure and function have been challenging to link to cognition due to potential overlapping influences of multiple neurobiological cascades. We examined multiple brain markers associated with age-related variation in cognition. Clinically normal older humans aged 65–90 from the Harvard Aging Brain Study (N = 186) were characterized on a priori magnetic resonance imaging markers of gray matter thickness and volume, white matter hyperintensities, fractional anisotropy (FA), resting-state functional connectivity, positron emission tomography markers of glucose metabolism and amyloid burden, and cognitive factors of processing speed, executive function, and episodic memory. Partial correlation and mediation analyses estimated age-related variance in cognition shared with individual brain markers and unique to each marker. The largest relationships linked FA and striatum volume to processing speed and executive function, and hippocampal volume to episodic memory. Of the age-related variance in cognition, 70–80% was accounted for by combining all brain markers (but only ∼20% of total variance). Age had significant indirect effects on cognition via brain markers, with significant markers varying across cognitive domains. These results suggest that most age-related variation in cognition is shared among multiple brain markers, but potential specificity between some brain markers and cognitive domains motivates additional study of age-related markers of neural health. PMID:25316342

  9. Linking Attitudes, Policy, and Forest Cover Change in Buffer Zone Communities of Chitwan National Park, Nepal

    Science.gov (United States)

    Stapp, Jared R.; Lilieholm, Robert J.; Leahy, Jessica; Upadhaya, Suraj

    2016-06-01

    Deforestation in Nepal threatens the functioning of complex social-ecological systems, including rural populations that depend on forests for subsistence, as well as Nepal's biodiversity and other ecosystem services. Nepal's forests are particularly important to the nation's poorest inhabitants, as many depend upon them for daily survival. Two-thirds of Nepal's population relies on forests for sustenance, and these pressures are likely to increase in the future. This, coupled with high population densities and growth rates, highlights the importance of studying the relationship between human communities, forest cover trends through time, and forest management institutions. Here, we used surveys to explore how household attitudes associated with conservation-related behaviors in two rural communities—one that has experienced significant forest loss, and the other forest gain—compare with forest cover trends as indicated by satellite-derived forest-loss and -regeneration estimates between 2005 and 2013. Results found a significant difference in attitudes in the two areas, perhaps contributing to and reacting from current forest conditions. In both study sites, participation in community forestry strengthened support for conservation, forest conservation-related attitudes aligned with forest cover trends, and a negative relationship was found between economic status and having supportive forest conservation-related attitudes. In addition, on average, respondents were not satisfied with their district forest officers and did not feel that the current political climate in Nepal supported sustainable forestry. These findings are important as Nepal's Master Plan for the Forestry Sector has expired and the country is in the process of structuring a new Forestry Sector Strategy.

  10. Linking Attitudes, Policy, and Forest Cover Change in Buffer Zone Communities of Chitwan National Park, Nepal.

    Science.gov (United States)

    Stapp, Jared R; Lilieholm, Robert J; Leahy, Jessica; Upadhaya, Suraj

    2016-06-01

    Deforestation in Nepal threatens the functioning of complex social-ecological systems, including rural populations that depend on forests for subsistence, as well as Nepal's biodiversity and other ecosystem services. Nepal's forests are particularly important to the nation's poorest inhabitants, as many depend upon them for daily survival. Two-thirds of Nepal's population relies on forests for sustenance, and these pressures are likely to increase in the future. This, coupled with high population densities and growth rates, highlights the importance of studying the relationship between human communities, forest cover trends through time, and forest management institutions. Here, we used surveys to explore how household attitudes associated with conservation-related behaviors in two rural communities-one that has experienced significant forest loss, and the other forest gain-compare with forest cover trends as indicated by satellite-derived forest-loss and -regeneration estimates between 2005 and 2013. Results found a significant difference in attitudes in the two areas, perhaps contributing to and reacting from current forest conditions. In both study sites, participation in community forestry strengthened support for conservation, forest conservation-related attitudes aligned with forest cover trends, and a negative relationship was found between economic status and having supportive forest conservation-related attitudes. In addition, on average, respondents were not satisfied with their district forest officers and did not feel that the current political climate in Nepal supported sustainable forestry. These findings are important as Nepal's Master Plan for the Forestry Sector has expired and the country is in the process of structuring a new Forestry Sector Strategy.

  11. US HealthLink: a national information resource for health care professionals.

    Science.gov (United States)

    Yasnoff, W A

    1992-06-01

    US HealthLink is a new, comprehensive online medical information system designed specifically for health care professionals. Available to individuals for a fixed fee, it includes literature, news, diagnostic decision support, drug interactions, electronic mail, and bulletin boards. It also provides user-specific current awareness via clipping service, and fax delivery of both clipping and electronic mail information. US HealthLink can now be utilized to access a wide variety of medical information sources inexpensively.

  12. The Link between National Foreign Policy and the Performance of a Country in the European Union: The Polish Case

    Directory of Open Access Journals (Sweden)

    Joanna Kaminska

    2010-05-01

    Full Text Available This article examines the link between the adaptation of national executives and diplomats to the EU and the capacity of a state to influence EU foreign policy outcomes. It argues that, in the case of Poland, the politicization of the domestic administrative structures before 2004 constrained the ability of the state to impact on the EU’s external agenda after the enlargement. It also claims that a rapid adaptation to the EU occurred only after the Polish accession to the EU, as the will to influence the EU’s policy towards Eastern Europe was a main driver for changes in the national diplomacy.

  13. Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs

    Directory of Open Access Journals (Sweden)

    Liang Kung-Yee

    2010-07-01

    Full Text Available Abstract Background Many dichotomous traits for complex diseases are often involved more than one locus and/or associated with quantitative biomarkers or environmental factors. Incorporating these quantitative variables into linkage analysis as well as localizing two linked disease loci simultaneously could therefore improve the efficiency in mapping genes. We extended the robust multipoint Identity-by-Descent (IBD approach with incorporation of covariates developed previously to simultaneously estimate two linked loci using different types of affected relative pairs (ARPs. Results We showed that the efficiency was enhanced by incorporating a quantitative covariate parametrically or non-parametrically while localizing two disease loci using ARPs. In addition to its help in identifying factors associated with the disease and in improving the efficiency in estimating disease loci, this extension also allows investigators to account for heterogeneity in risk-ratios for different ARPs. Data released from the collaborative study on the genetics of alcoholism (COGA for Genetic Analysis Workshop 14 (GAW 14 were used to illustrate the application of this extended method. Conclusions The simulation studies and example illustrated that the efficiency in estimating disease loci was demonstratively enhanced by incorporating a quantitative covariate and by using all relative pairs while mapping two linked loci simultaneously.

  14. Linking the Revised National Standards to Teaching Games for Understanding: An Eighth-Grade Soccer Example

    Science.gov (United States)

    Parkes, Craig; Subramaniam, Prithwi Raj

    2015-01-01

    In the United States it is estimated that over 3 million children and young people currently participate in youth soccer programs. This number has the potential to increase following a surge of interest in the U.S. Men's National Team World Cup performance in Brazil in 2014, and the U.S. Women's National Team World Cup win in Canada in 2015. This…

  15. Towards a National Discursive Construction of Nurses' Diversity Related Competencies?

    DEFF Research Database (Denmark)

    Jensen, Annie Aarup; Jæger, Kirsten

    2009-01-01

    's journal, "The Nurse", covering an eight-year period it is concluded that the nursing profession understood as a community of practice continues to encounter the same type of problems related to diversity and that increased knowledge, skills and competencies are needed. The discourse of a new Bachelor......This paper will explore the premises for developing a national discursive construction of the professional competencies needed by nurses when confronted with cultural difference and intercultural contact. Based on an analysis of the Danish nursing community's articles in the Danish Nursing Union...... degree programme in nursing containing a national, standardised curriculum is therefore analysed to uncover how cultural difference and intercultural issues are prioritised in terms of learning goals and resources, and to examine whether the discourse contributes significantly to the understanding...

  16. Performance of adaptive DD-OFDM multicore fiber links and its relation with intercore crosstalk.

    Science.gov (United States)

    Alves, Tiago M F; Luís, Ruben S; Puttnam, Benjamin J; Cartaxo, Adolfo V T; Awaji, Yoshinari; Wada, Naoya

    2017-07-10

    Adaptive direct-detection (DD) orthogonal frequency-division multiplexing (OFDM) is proposed to guarantee signal quality over time in weakly-coupled homogenous multicore fiber (MCFs) links impaired by stochastic intercore crosstalk (ICXT). For the first time, the received electrical power of the ICXT and the performance of the adaptive DD-OFDM MCF link are experimentally monitored quasi-simultaneously over a 210 hour period. Experimental results show that the time evolution of the error vector magnitude due to the ICXT can be suitably estimated from the normalized power of the detected crosstalk. The detected crosstalk results from the beating between the carrier in the test core and ICXT originating from the carrier and modulated signal from interfering core. The results show that the operation of DD-OFDM systems employing fixed modulation can be severely impaired by the presence of ICXT that may unpredictable vary in both power and frequency. The system may suffer from deleterious impact of moderate ICXT levels over a time duration of several hours or from peak ICXT levels occurring over a number of minutes. Such power fluctuations can lead to large variations in bit error ratio (BER) for static modulation schemes. Here, we show that BER fluctuations may be minimized by the use of adaptive modulation techniques and that in particular, the adaptive OFDM is a viable solution to guarantee link quality in MCF-based systems. An experimental model of an adaptive DD-OFDM MCF link shows an average throughput of 12 Gb/s that represents a reduction of only 9% compared to the maximum throughput measured without ICXT and an improvement of 23% relative to throughput obtained with static modulation.

  17. Towards a National Discursive Construction of Nurses' Diversity Related Competencies?

    DEFF Research Database (Denmark)

    Jensen, Annie Aarup; Jæger, Kirsten

    2009-01-01

    This paper will explore the premises for developing a national discursive construction of the professional competencies needed by nurses when confronted with cultural difference and intercultural contact. Based on an analysis of the Danish nursing community's articles in the Danish Nursing Union......'s journal, "The Nurse", covering an eight-year period it is concluded that the nursing profession understood as a community of practice continues to encounter the same type of problems related to diversity and that increased knowledge, skills and competencies are needed. The discourse of a new Bachelor...

  18. Convoys of Social Relations in Cross-National Context.

    Science.gov (United States)

    Ajrouch, Kristine J; Fuller, Heather R; Akiyama, Hiroko; Antonucci, Toni C

    2018-05-08

    This study examines national variations in social networks among older adults across 4 countries in diverse regions of the world: Japan, Lebanon, Mexico, and the United States. The aim is to provide insights into universal as well as unique attributes of social networks in later life. The analyses examine convoy characteristics among adults aged 50+ in metropolitan areas of Japan (N = 557), Lebanon (N = 284), Mexico (N = 556), and the United States (N = 583). Data were collected using the hierarchical mapping technique on representative samples in each locale. Multilevel models were conducted by nation to examine whether convoy characteristics vary by age and closeness. Network size and geographic proximity were dimensions of social networks sensitive to national context. By contrast, how age and feelings of closeness varied with contact frequency and the presence of children in networks revealed universal patterns. Furthermore, feelings of closeness varied by age with regard to size and contact frequency in Lebanon, proximity in Japan, and composition in Mexico. Identifying universal and unique characteristics of social networks in later life provide a preliminary empirical basis upon which to advance a global perspective on convoys of social relations and how they inform policies that can facilitate health and well-being among middle-aged and older people around the world.

  19. 76 FR 40937 - Public Availability of National Labor Relations Board's FY 2010 Service Contract Inventory

    Science.gov (United States)

    2011-07-12

    ... NATIONAL LABOR RELATIONS BOARD Public Availability of National Labor Relations Board's FY 2010 Service Contract Inventory AGENCY: National Labor Relations Board. ACTION: Notice of public availability... Consolidated Appropriations Act of 2010 (Pub. L. 111-117), the National Labor Relations Board (NLRB) is...

  20. 77 FR 5062 - Public Availability of National Labor Relations Board's FY 2011 Service Contract Inventory

    Science.gov (United States)

    2012-02-01

    ... NATIONAL LABOR RELATIONS BOARD Public Availability of National Labor Relations Board's FY 2011 Service Contract Inventory AGENCY: National Labor Relations Board. ACTION: Notice of public availability... Consolidated Appropriations Act of 2010 (Pub. L. 111-117), the National Labor Relations Board (NLRB) is...

  1. Linking carbon and water relations to drought-induced mortality in Pinus flexilis seedlings.

    Science.gov (United States)

    Reinhardt, Keith; Germino, Matthew J; Kueppers, Lara M; Domec, Jean-Christophe; Mitton, Jeffry

    2015-07-01

    Survival of tree seedlings at high elevations has been shown to be limited by thermal constraints on carbon balance, but it is unknown if carbon relations also limit seedling survival at lower elevations, where water relations may be more important. We measured and modeled carbon fluxes and water relations in first-year Pinus flexilis seedlings in garden plots just beyond the warm edge of their natural range, and compared these with dry-mass gain and survival across two summers. We hypothesized that mortality in these seedlings would be associated with declines in water relations, more so than with carbon-balance limitations. Rather than gradual declines in survivorship across growing seasons, we observed sharp, large-scale mortality episodes that occurred once volumetric soil-moisture content dropped below 10%. By this point, seedling water potentials had decreased below -5 MPa, seedling hydraulic conductivity had decreased by 90% and seedling hydraulic resistance had increased by >900%. Additionally, non-structural carbohydrates accumulated in aboveground tissues at the end of both summers, suggesting impairments in phloem-transport from needles to roots. This resulted in low carbohydrate concentrations in roots, which likely impaired root growth and water uptake at the time of critically low soil moisture. While photosynthesis and respiration on a leaf area basis remained high until critical hydraulic thresholds were exceeded, modeled seedling gross primary productivity declined steadily throughout the summers. At the time of mortality, modeled productivity was insufficient to support seedling biomass-gain rates, metabolism and secondary costs. Thus the large-scale mortality events that we observed near the end of each summer were most directly linked with acute, episodic declines in plant hydraulic function that were linked with important changes in whole-seedling carbon relations. © The Author 2015. Published by Oxford University Press. All rights reserved

  2. Neighborhood linking social capital as a predictor of drug abuse: A Swedish national cohort study.

    Science.gov (United States)

    Sundquist, Jan; Sjöstedt, Cecilia; Winkleby, Marilyn; Li, Xinjun; Kendler, Kenneth S; Sundquist, Kristina

    2016-12-01

    This study examines the association between the incidence of drug abuse (DA) and linking (communal) social capital, a theoretical concept describing the amount of trust between individuals and societal institutions. We present results from an 8-year population-based cohort study that followed all residents in Sweden, aged 15-44, from 2003 through 2010, for a total of 1,700,896 men and 1,642,798 women. Linking social capital was conceptualized as the proportion of people in a geographically defined neighborhood who voted in local government elections. Multilevel logistic regression was used to estimate odds ratios (ORs) and between-neighborhood variance. We found robust associations between linking social capital and DA in men and women. For men, the OR for DA in the crude model was 2.11 [95% confidence interval (CI) 2.02-2.21] for those living in neighborhoods with the lowest vs. highest level of social capital. After accounting for neighborhood level deprivation, the OR fell to 1.59 (1.51-1-68). The ORs remained significant after accounting for age, family income, marital status, country of birth, education level, and region of residence, and after further accounting for comorbidities and family history of comorbidities and family history of DA. For women, the OR decreased from 2.15 (2.03-2.27) in the crude model to 1.31 (1.22-1.40) in the final model, adjusted for multiple neighborhood-level, individual-level variables, and family history for DA. Our study suggests that low linking social capital may have significant independent effects on DA. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Transnational caregiving: Part 1, caring for family relations across nations.

    Science.gov (United States)

    Dhar, V Erica

    2011-01-01

    This article concerns how globalization and the aging of the world's population are affecting the already complex issue of intergenerational transnational caregiving. Globalization has caused an increase in workforce mobility with large numbers of individuals seeking employment overseas. This, coupled with increased longevity globally, has resulted in many workers leaving their elderly parents in need of care in their home countries. This has spawned caregiving across national borders, or caring for family relations across nations. Currently in the United States, not enough emphasis is given to family caregiving. Data compiled by AARP and the National Alliance for Caregiving estimate the economic value for this group of family caregivers in 2007 to be $375 billion, accounting for 34-52 million family caregivers per given year. This does not include those families who are transnational caregivers. The seminal work in this emerging field has been done by social anthropologists Loretta Baldassar, Cora Velekoop Baldock, and Raelene Wilding, who have defined the components of transnational caregiving based on an ethnographic study using qualitative data to study nine immigrant communities in Western Australia. Although their research focused on caregiving from a distance, additional work has been added to the discussion by introducing the element of "care drain" and further cultural perspectives. Therefore, this research is an exploratory study on intergenerational transnational caregiving within the context of the changing world and its demographics. Within the context of globalization and global aging, the following questions are addressed: What is the significance of family caregiving? What is a transnational? How has technology changed "transnationalism" today? What are the elements that comprise transnational caregiving? How does culture play a role in transnational caregiving? What are some of the national initiatives undertaken by governments to aid in workforce

  4. Relative age effects in Australian Football League National Draftees.

    Science.gov (United States)

    Coutts, Aaron J; Kempton, Thomas; Vaeyens, Roel

    2014-01-01

    This study examined the birth distribution for adolescent (i.e. born in the first part of the classification period for both quartile (P born in the latter part of the selection period for both quartile (P = 0.047) and half-year (P = 0.028) compared to the Australian national population. The selection bias towards relatively older players in adolescent AFL draftees may be related to advanced physical and psychological maturity, and exposure to higher-level coaching compared to their younger counterparts. The reverse RAE in mature age draftees is a novel finding and supports the need for strategies to encourage continued participation pathways for talented Australian football players born later in the selection year.

  5. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability.

    Science.gov (United States)

    Colotta, Francesco; Allavena, Paola; Sica, Antonio; Garlanda, Cecilia; Mantovani, Alberto

    2009-07-01

    Inflammatory conditions in selected organs increase the risk of cancer. An inflammatory component is present also in the microenvironment of tumors that are not epidemiologically related to inflammation. Recent studies have begun to unravel molecular pathways linking inflammation and cancer. In the tumor microenvironment, smoldering inflammation contributes to proliferation and survival of malignant cells, angiogenesis, metastasis, subversion of adaptive immunity, reduced response to hormones and chemotherapeutic agents. Recent data suggest that an additional mechanism involved in cancer-related inflammation (CRI) is induction of genetic instability by inflammatory mediators, leading to accumulation of random genetic alterations in cancer cells. In a seminal contribution, Hanahan and Weinberg [(2000) Cell, 100, 57-70] identified the six hallmarks of cancer. We surmise that CRI represents the seventh hallmark.

  6. The link between health governance models and global health innovation: an exploration of OECD nations.

    Science.gov (United States)

    Schnarr, Karin; Snowdon, Anne; Cramm, Heidi; Cohen, Jason; Alessi, Charles

    2015-01-01

    While there is established research that explores individual innovations across countries or developments in a specific health area, there is less work that attempts to match national innovations to specific systems of health governance to uncover themes across nations. We used a cross-comparison design that employed content analysis of health governance models and innovation patterns in eight OECD nations (Australia, Britain, Canada, France, Germany, The Netherlands, Switzerland, and the United States). Country-level model of health governance may impact the focus of health innovation within the eight jurisdictions studied. Innovation across all governance models has targeted consumer engagement in health systems, the integration of health services across the continuum of care, access to care in the community, and financial models that drive competition. Improving our understanding of the linkage between health governance and innovation in health systems may heighten awareness of potential enablers and barriers to innovation success.

  7. The Link between National Paid Leave Policy and Work-Family Conflict among Married Working Parents

    NARCIS (Netherlands)

    Allen, T.D.; Lapierre, L.M.; Spector, P.E.; Poelmans, S.A.Y.; O'Driscoll, M.P.; Sanchez, J.I.; Cooper, G.L.; Walvoord, A.G.; Antoniou, A.S.; Brough, P.; Geurts, S.A.E.; Kinnunen, U.; Pagon, M.; Shima, S.; Woo, J.M.

    2014-01-01

    We investigated relationships between four dimensions of work–family conflict (time- and strain-based work interference with family, time- and strain-based family interference with work) and three key national paid leave policies (paid parental leave, paid sick leave, paid annual leave) among a

  8. Ethnic Variations of Pathways Linking Socioeconomic Status, Parenting, and Preacademic Skills in a Nationally Representative Sample

    Science.gov (United States)

    Iruka, Iheoma U.; Dotterer, Aryn M.; Pungello, Elizabeth P.

    2014-01-01

    Research Findings: Grounded in the investment model and informed by the integrative theory of the study of minority children, this study used the Early Childhood Longitudinal Study-Birth Cohort data set, a nationally representative sample of young children, to investigate whether the association between socioeconomic status (family income and…

  9. Reluctant Partners in Modernization: The National Autonomous University of Mexico and Its Links with Industry.

    Science.gov (United States)

    Castanos-Lomnitz, Heriberta

    1997-01-01

    Analyzes interviews with 44 Mexicans representative of industry, government, and the National Autonomous University of Mexico concerning modernization, industrialization, and technology transfer in the context of higher education. Although all supported an active role for higher education in technology transfer in public statements, they were…

  10. Linking community-based and national REDD+ monitoring: a review of the potential

    NARCIS (Netherlands)

    Pratihast, A.K.; Herold, M.; Sy, de V.; Murdiyarso, D.; Skutsch, M.

    2013-01-01

    Countries participating in REDD+ schemes are required to establish a national monitoring system that keeps track of forest carbon changes over time. Community-based monitoring (CBM) can be useful for tracking locally driven forest change activities and their impacts. In this paper, we review some of

  11. National Identification and Intercultural Relations in Foreign Language Learning

    Science.gov (United States)

    Rivers, Damian J.

    2010-01-01

    Framed within debates concerning national identification and English as a Foreign Language education within Japan, the current study explores the relationships between three specific attitudinal facets of Japanese national identification (internationalism, patriotism and nationalism), the perceived vitality of English-speaking nations, the…

  12. Developments related to the National Nuclear Safety Authority of Romania

    International Nuclear Information System (INIS)

    Baciu, Florin

    1998-01-01

    The contribution presents the status of the National Commission for Nuclear Activity Control (CNCAN) as indicated by the provisions of a Romanian Government Decision of May 1998. As specified in the art.3 the main tasks of the Commission are the following: to issue authorization and exercise permits of activities in nuclear field; to supervise the applications of the provisions stipulated by the law concerning development in safety conditions of nuclear activities; to develop instructions as well as nuclear safety regulations to ensure the quality assurance and functioning in safety conditions of the nuclear facilities and plants, the protection against nuclear radiation of the professionally exposed personnel, of the population, of the environment and of the material goods, the physical protection, the records, preservation and transport of radioactive material and of fissionable materials as well as the management of radioactive waste; organizes expert and is responsible for the state control concerning the integrated application of the law provisions in the field of quality constructions in which nuclear installations of national interest are located, during all the phases and for all the components of the quality system in this field; issues specialty and information documentation specific to its own activity, provides the information of the public through official publication, official statements to the press and other specific form of information; carries out any other tasks provided by law in the field of regulations and control of nuclear activity. Author presents also the CNCAN staff number evolution, the new structure, the staff distribution at headquarters, local agencies and national radiation monitoring network. Finally, the author discusses the legal provisions related to management manual procedures

  13. Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention

    Directory of Open Access Journals (Sweden)

    Andrew T. Ludlow

    2011-01-01

    Full Text Available Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence of the molecular and cellular factors associated with reduced disease risk and increased longevity resulting from physical activity is sparse. A long-standing hypothesis of aging is the telomere hypothesis: as a cell divides, telomeres shorten resulting eventually in replicative senescence and an aged phenotype. Several reports have recently associated telomeres and telomere-related proteins to diseases associated with physical inactivity and aging including cardiovascular disease, insulin resistance, and hypertension. Interestingly several reports have also shown that longer telomeres are associated with higher physical activity levels, indicating a potential mechanistic link between physical activity, reduced age-related disease risk, and longevity. The primary purpose of this review is to discuss the potential importance of physical activity in telomere biology in the context of inactivity- and age-related diseases. A secondary purpose is to explore potential mechanisms and important avenues for future research in the field of telomeres and diseases associated with physical inactivity and aging.

  14. Firework-related childhood injuries in Greece: a national problem.

    Science.gov (United States)

    Vassilia, Konte; Eleni, Petridou; Dimitrios, Trichopoulos

    2004-03-01

    During a 5-year period, out of 110066 children with injuries recorded in the Greek Emergency Department Injury Surveillance System (EDISS), 91 had firework-related injuries. Descriptive analyses and the Barrell matrix were used to determine risk factors and extrapolated national firework childhood injury figures were calculated. The estimated annual incidence of childhood firework injuries treated in the emergency departments of hospitals countrywide, was 7 per 100000 children years. Seventy percent of injuries concerned older children (10-14 years), mostly boys with self-inflicted injuries, whereas girls suffered injuries as bystanders. A sharp peak in spring was noted, when the Greek Orthodox Easter is celebrated. Illicitly sold fireworks caused most injuries, but in eight instances homemade firecrackers were responsible.

  15. College drinking behaviors: mediational links between parenting styles, impulse control, and alcohol-related outcomes.

    Science.gov (United States)

    Patock-Peckham, Julie A; Morgan-Lopez, Antonio A

    2006-06-01

    Mediational links between parenting styles (authoritative, authoritarian, permissive), impulsiveness (general control), drinking control (specific control), and alcohol use and abuse were tested. A pattern-mixture approach (for modeling non-ignorable missing data) with multiple-group structural equation models with 421 (206 female, 215 male) college students was used. Gender was examined as a potential moderator of parenting styles on control processes related to drinking. Specifically, the parent-child gender match was found to have implications for increased levels of impulsiveness (a significant mediator of parenting effects on drinking control). These findings suggest that a parent with a permissive parenting style who is the same gender as the respondent can directly influence control processes and indirectly influence alcohol use and abuse.

  16. The national public's values and interests related to the Arctic National Wildlife Refuge: A computer content analysis

    Science.gov (United States)

    David N. Bengston; David P. Fan; Roger Kaye

    2010-01-01

    This study examined the national public's values and interests related to the Arctic National Wildlife Refuge. Computer content analysis was used to analyze more than 23,000 media stories about the refuge from 1995 through 2007. Ten main categories of Arctic National Wildlife Refuge values and interests emerged from the analysis, reflecting a diversity of values,...

  17. Testing links between childhood positive peer relations and externalizing outcomes through a randomized controlled intervention study.

    Science.gov (United States)

    Witvliet, Miranda; van Lier, Pol A C; Cuijpers, Pim; Koot, Hans M

    2009-10-01

    In this study, the authors used a randomized controlled trial to explore the link between having positive peer relations and externalizing outcomes in 758 children followed from kindergarten to the end of 2nd grade. Children were randomly assigned to the Good Behavior Game (GBG), a universal classroom-based preventive intervention, or a control condition. Children's acceptance by peers, their number of mutual friends, and their proximity to others were assessed annually through peer ratings. Externalizing behavior was annually rated by teachers. Reductions in children's externalizing behavior and improvements in positive peer relations were found among GBG children, as compared with control-group children. Reductions in externalizing behavior appeared to be partly mediated by the improvements in peer acceptance. This mediating role of peer acceptance was found for boys only. The results suggest that positive peer relations are not just markers, but they are environmental mediators of boys' externalizing behavior development. Implications for research and prevention are discussed. (c) 2009 APA, all rights reserved.

  18. Sagittal synostosis in X-linked hypophosphatemic rickets and related diseases

    Energy Technology Data Exchange (ETDEWEB)

    Currarino, Guido [Texas Scottish Rite Hospital, Department of Radiology, Dallas, TX (United States)

    2007-08-15

    The recent observations of two new cases of X-linked hypophosphatemic rickets associated with premature closure of the sagittal suture prompted a review of similar cases seen in this institution. To review the clinical records and skull radiographs of 28 children with hypophosphatemic rickets in order to investigate the frequency and type of craniosynostosis and other cranial vault changes seen in these conditions and to review the literature for relevant findings. Clinical and imaging records were reviewed on 28 patients with hypophosphatemic rickets, all younger than 18 years. Most patients had X-linked hypophosphatemic rickets and a few had autosomal-dominant hypophosphatemic rickets or were non-familial cases. Of the 28 patients, 13 had sagittal synostosis. Dolichocephaly was present in ten patients. The configuration of the cranial vault in some of these ten patients with dolichocephaly varied somewhat from that seen in nonsyndromic sagittal synostosis. In one patient, a Chiari I malformation was demonstrated by MRI. In another patient with increased intracranial pressure the sagittal suture closure was associated with lambdoidal synostosis. Dolichocephaly was not present in three patients, suggesting that the synostosis started later than in the other patients, probably in the second year of life, a period of slower brain growth than in the first year. The two patients in this group of three showed thickening and sclerosis of the cranial vault of uncertain etiology. There is an increased risk of sagittal synostosis in hypophosphatemic rickets and related diseases in children. The appearance of the cranial vault in this type of synostosis can vary from that seen in nonsyndromic synostosis. In this setting, careful clinical and imaging follow-up is warranted. (orig.)

  19. Sagittal synostosis in X-linked hypophosphatemic rickets and related diseases

    International Nuclear Information System (INIS)

    Currarino, Guido

    2007-01-01

    The recent observations of two new cases of X-linked hypophosphatemic rickets associated with premature closure of the sagittal suture prompted a review of similar cases seen in this institution. To review the clinical records and skull radiographs of 28 children with hypophosphatemic rickets in order to investigate the frequency and type of craniosynostosis and other cranial vault changes seen in these conditions and to review the literature for relevant findings. Clinical and imaging records were reviewed on 28 patients with hypophosphatemic rickets, all younger than 18 years. Most patients had X-linked hypophosphatemic rickets and a few had autosomal-dominant hypophosphatemic rickets or were non-familial cases. Of the 28 patients, 13 had sagittal synostosis. Dolichocephaly was present in ten patients. The configuration of the cranial vault in some of these ten patients with dolichocephaly varied somewhat from that seen in nonsyndromic sagittal synostosis. In one patient, a Chiari I malformation was demonstrated by MRI. In another patient with increased intracranial pressure the sagittal suture closure was associated with lambdoidal synostosis. Dolichocephaly was not present in three patients, suggesting that the synostosis started later than in the other patients, probably in the second year of life, a period of slower brain growth than in the first year. The two patients in this group of three showed thickening and sclerosis of the cranial vault of uncertain etiology. There is an increased risk of sagittal synostosis in hypophosphatemic rickets and related diseases in children. The appearance of the cranial vault in this type of synostosis can vary from that seen in nonsyndromic synostosis. In this setting, careful clinical and imaging follow-up is warranted. (orig.)

  20. Gender-specific mediational links between parenting styles, parental monitoring, impulsiveness, drinking control, and alcohol-related problems.

    Science.gov (United States)

    Patock-Peckham, Julie A; King, Kevin M; Morgan-Lopez, Antonio A; Ulloa, Emilio C; Moses, Jennifer M Filson

    2011-03-01

    Recently, it has been suggested that traits may dynamically change as conditions change. One possible mechanism that may influence impulsiveness is parental monitoring. Parental monitoring reflects a knowledge regarding one's offspring's whereabouts and social connections. The aim of this investigation was to examine potential gender-specific parental influences to impulsiveness (general behavioral control), control over one's own drinking (specific behavioral control), and alcohol-related problems among individuals in a period of emerging adulthood. Direct and mediational links between parenting styles (permissive, authoritarian, and authoritative), parental monitoring, impulsiveness, drinking control, and alcohol-related problems were investigated. A multiple-group, SEM model with (316 women, 265 men) university students was examined. In general, the overall pattern among male and female respondents was distinct. For daughters, perceptions of a permissive father were indirectly linked to more alcohol-related problems through lower levels of monitoring by fathers and more impulsive symptoms. Perceptions of an authoritative father were also indirectly linked to fewer impulsive symptoms through higher levels of monitoring by fathers among daughters. For men, perceptions of a permissive mother were indirectly linked to more alcohol-related problems through lower levels of monitoring by mothers and more impulsive symptoms. For sons, perceptions of mother authoritativeness were indirectly linked to fewer alcohol-related problems through more monitoring by mothers and fewer impulsive symptoms. Monitoring by an opposite-gender parent mediated the link between parenting styles (i.e., permissive, authoritative) on impulsiveness.

  1. Shame and Alienation Related to Child Maltreatment: Links to Symptoms Across Generations.

    Science.gov (United States)

    Babcock Fenerci, Rebecca L; DePrince, Anne P

    2017-11-20

    The current study investigated associations between appraisals of shame and alienation related to mothers' own experiences of child maltreatment and symptoms across generations-in mothers themselves as well as their toddler/preschool-aged children. Mothers who survived maltreatment (N = 113) with a child between the ages of 2 and 5 were recruited to participate in an online study on Maternal Coping, Attachment and Health. Mother participants completed a series of questionnaires, including those that asked about posttrauma appraisals of their own maltreatment experiences as well as their child's and their own mental health symptoms. When taking into account other posttrauma appraisals (e.g., fear, betrayal, anger, self-blame), maternal shame and alienation were both significantly associated with maternal trauma-related distress (a composite of anxiety, PTSD, dissociation, and depressive symptoms). Maternal shame was also significantly linked to child internalizing symptoms and externalizing symptoms. Lower levels of fear and higher levels of betrayal were associated with externalizing symptoms as well. Maternal trauma-related distress mediated the relationship between maternal shame and child externalizing symptoms, and partially mediated the relationship between shame and internalizing symptoms. This study is the first of its kind to examine the role of posttrauma appraisals among mother survivors of maltreatment as they relate to symptoms in their young children. Although additional research is necessary, findings suggest that mothers' posttrauma appraisals, such as shame, could be a relevant factor in the early social-emotional development of survivors' children. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  2. Linking families and facilities for care at birth: What works to avert intrapartum-related deaths?

    Science.gov (United States)

    Lee, Anne CC; Lawn, Joy E.; Cousens, Simon; Kumar, Vishwajeet; Osrin, David; Bhutta, Zulfiqar A.; Wall, Steven N.; Nandakumar, Allyala K.; Syed, Uzma; Darmstadt, Gary L.

    2012-01-01

    Background Delays in receiving effective care during labor and at birth may be fatal for the mother and fetus, contributing to 2 million annual intrapartum stillbirths and intrapartum-related neonatal deaths each year. Objective We present a systematic review of strategies to link families and facilities, including community mobilization, financial incentives, emergency referral and transport systems, prenatal risk screening, and maternity waiting homes. Results There is moderate quality evidence that community mobilization with high levels of community engagement can increase institutional births and significantly reduce perinatal and early neonatal mortality. Meta-analysis showed a doubling of skilled birth attendance and a 35% reduction in early neonatal mortality. However, no data are available on intrapartum-specific outcomes. Evidence is limited, but promising, that financial incentive schemes and community referral/transport systems may increase rates of skilled birth attendance and emergency obstetric care utilization; however, impact on mortality is unknown. Current evidence for maternity waiting homes and risk screening is low quality. Conclusions Empowering communities is an important strategy to reduce the large burden of intrapartum complications. Innovations are needed to bring the poor closer to obstetric care, such as financial incentives and cell phone technology. New questions need to be asked of “old” strategies such as risk screening and maternity waiting homes. The effect of all of these strategies on maternal and perinatal mortality, particularly intrapartum-related outcomes, requires further evaluation. PMID:19815201

  3. Synaptic Effects of Dopamine Breakdown and Their Relation to Schizophrenia-Linked Working Memory Deficits

    Directory of Open Access Journals (Sweden)

    Andrew D. Bolton

    2018-06-01

    Full Text Available Working memory is the ability to hold information “online” over a time delay in order to perform a task. This kind of memory is encoded in the brain by persistent neural activity that outlasts the presentation of a stimulus. Patients with schizophrenia perform poorly in working memory tasks that require the brief memory of a target location in space. This deficit indicates that persistent neural activity related to spatial locations may be impaired in the disease. At the circuit level, many studies have shown that NMDA receptors and the dopamine system are involved in both schizophrenia pathology and working memory-related persistent activity. In this Hypothesis and Theory article, we examine the possible connection between NMDA receptors, the dopamine system, and schizophrenia-linked working memory deficits. In particular, we focus on the dopamine breakdown product homocysteine (HCY, which is consistently elevated in schizophrenia patients. Our previous studies have shown that HCY strongly reduces the desensitization of NMDA currents. Here, we show that HCY likely affects NMDA receptors in brain regions that support working memory; this is because these areas favor dopamine breakdown over transport to clear dopamine from synapses. Finally, within the context of two NMDA-based computational models of working memory, we suggest a mechanism by which HCY could give rise to the working memory deficits observed in schizophrenia patients.

  4. Medical Care Tasks among Spousal Dementia Caregivers: Links to Care-Related Sleep Disturbances.

    Science.gov (United States)

    Polenick, Courtney A; Leggett, Amanda N; Maust, Donovan T; Kales, Helen C

    2018-05-01

    Medical care tasks are commonly provided by spouses caring for persons living with dementia (PLWDs). These tasks reflect complex care demands that may interfere with sleep, yet their implications for caregivers' sleep outcomes are unknown. The authors evaluated the association between caregivers' medical/nursing tasks (keeping track of medications; managing tasks such as ostomy care, intravenous lines, or blood testing; giving shots/injections; and caring for skin wounds/sores) and care-related sleep disturbances. A retrospective analysis of cross-sectional data from the 2011 National Health and Aging Trends Study and National Study of Caregiving was conducted. Spousal caregivers and PLWDs/proxies were interviewed by telephone at home. The U.S. sample included 104 community-dwelling spousal caregivers and PLWDs. Caregivers reported on their sociodemographic and health characteristics, caregiving stressors, negative caregiving relationship quality, and sleep disturbances. PLWDs (or proxies) reported on their health conditions and sleep problems. Caregivers who performed a higher number of medical/nursing tasks reported significantly more frequent care-related sleep disturbances, controlling for sociodemographic and health characteristics, caregiving stressors, negative caregiving relationship quality, and PLWDs' sleep problems and health conditions. Post hoc tests showed that wound care was independently associated with more frequent care-related sleep disturbances after accounting for the other medical/nursing tasks and covariates. Spousal caregivers of PLWDs who perform medical/nursing tasks may be at heightened risk for sleep disturbances and associated adverse health consequences. Interventions to promote the well-being of both care partners may benefit from directly addressing caregivers' needs and concerns about their provision of medical/nursing care. Copyright © 2018 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights

  5. Data Systems Linking Resources to Actions and Outcomes: One of the Nation's Most Pressing Education Challenges

    Science.gov (United States)

    Guthrie, James W.

    2007-01-01

    The inadequacy of present-day public school financial and performance reporting restricts policymakers. With existing spending and activity information now generally available, public officials can determine only overall education resource levels and make allocative decisions only among gross input categories such as relative amounts of labor and…

  6. A Tri-National program for estimating the link between snow resources and hydrological droughts

    Directory of Open Access Journals (Sweden)

    M. Zappa

    2015-06-01

    Full Text Available To evaluate how summer low flows and droughts are affected by the winter snowpack, a Tri-National effort will analyse data from three catchments: Alpbach (Prealps, central Switzerland, Gudjaretis-Tskali (Little Caucasus, central Georgia, and Kamenice (Jizera Mountains, northern Czech Republic. Two GIS-based rainfall-runoff models will simulate over 10 years of runoff in streams based on rain and snowfall measurements, and further meteorological variables. The models use information on the geographical settings of the catchments together with knowledge of the hydrological processes of runoff generation from rainfall, looking particularly at the relationship between spring snowmelt and summer droughts. These processes include snow accumulation and melt, evapotranspiration, groundwater recharge in spring that contributes to (the summer runoff, and will be studied by means of the environmental isotopes 18O and 2H. Knowledge about the isotopic composition of the different water sources will allow to identify the flow paths and estimate the residence time of snow meltwater in the subsurface and its contribution to the stream. The application of the models in different nested or neighbouring catchments will explore their potential for further development and allow a better early prediction of low-flow periods in various mountainous zones across Europe. The paper presents the planned activities including a first analysis of already available dataset of environmental isotopes, discharge, snow water equivalent and modelling experiments of the (already available datasets.

  7. Linking NASA Environmental Data with a National Public Health Cohort Study and a CDC On-Line System to Enhance Public Health Decision Making

    Science.gov (United States)

    Al-Hamdan, Mohammad; Crosson, William; Economou, Sigrid; Estes, Maurice, Jr.; Estes, Sue; Hemmings, Sarah; Kent, Shia; Puckett, Mark; Quattrochi, Dale; Wade, Gina; hide

    2012-01-01

    The overall goal of this study is to address issues of environmental health and enhance public health decision making by utilizing NASA remotely-sensed data and products. This study is a collaboration between NASA Marshall Space Flight Center, Universities Space Research Association (USRA), the University of Alabama at Birmingham (UAB) School of Public Health and the Centers for Disease Control and Prevention (CDC) National Center for Public Health Informatics. The objectives of this study are to develop high-quality spatial data sets of environmental variables, link these with public health data from a national cohort study, and deliver the linked data sets and associated analyses to local, state and federal end-user groups. Three daily environmental data sets were developed for the conterminous U.S. on different spatial resolutions for the period 2003-2008: (1) spatial surfaces of estimated fine particulate matter (PM2.5) exposures on a 10-km grid utilizing the US Environmental Protection Agency (EPA) ground observations and NASA s MODerate-resolution Imaging Spectroradiometer (MODIS) data; (2) a 1-km grid of Land Surface Temperature (LST) using MODIS data; and (3) a 12-km grid of daily Solar Insolation (SI) and maximum and minimum air temperature using the North American Land Data Assimilation System (NLDAS) forcing data. These environmental datasets were linked with public health data from the UAB REasons for Geographic and Racial Differences in Stroke (REGARDS) national cohort study to determine whether exposures to these environmental risk factors are related to cognitive decline and other health outcomes. These environmental national datasets will also be made available to public health professionals, researchers and the general public via the CDC Wide-ranging Online Data for Epidemiologic Research (WONDER) system, where they can be aggregated to the county, state or regional level as per users need and downloaded in tabular, graphical, and map formats. The

  8. Linking emotional distress to unhealthy sleep duration: analysis of the 2009 National Health Interview Survey

    Directory of Open Access Journals (Sweden)

    Seixas AA

    2015-09-01

    Full Text Available Azizi A Seixas,1 Joao V Nunes,2 Collins O Airhihenbuwa,3 Natasha J Williams,1 Seithikurippu Ratnas Pandi-Perumal,1 Caryl C James,4 Girardin Jean-Louis11Center for Healthful Behavior Change, Department of Population Health, Division of Population Health, New York University School of Medicine, 2Sophie Davis School of Biomedical Education, City College of New York, New York, NY, USA; 3Department of Biobehavioral Health, The Pennsylvania State University, State College, PA, USA; 4Department of Sociology, Psychology and Social Work, The University of the West Indies, Mona, JamaicaObjective: The objective of the study was to examine the independent association of emotional distress with unhealthy sleep duration (defined as <7 or >8 hours.Methods: Data from the 2009 National Health Interview Survey (NHIS, a cross-sectional household survey, were analyzed to investigate the associations of emotional distress with unhealthy sleep durations, adjusting for sociodemographic factors, health risks, and chronic diseases through hierarchical multiple logistic regression analysis.Participants: A total of 27,731 participants (age range 18–85 years from the NHIS 2009 dataset were interviewed.Measures: Unhealthy sleep duration is defined as sleep duration <7 or >8 hours, whereas healthy sleep is defined as sleep duration lasting for 7–8 hours. Emotional distress is based on the Kessler 6 Non-Specific Distress Battery, which assesses the frequency of feeling sad, nervous, restless, hopeless, worthless, and burdened, over a 30-day period.Results: Of the sample, 51.7% were female; 83.1% were white and 16.9% were black. Eleven percent experienced emotional distress and 37.6% reported unhealthy sleep. Adjusted logistic regression analysis revealed that individuals with emotional distress had 55% greater odds of reporting unhealthy sleep (odds ratio [OR] =1.55, 95% confidence interval [CI] =1.42, 1.68, P<0.001.Conclusion: Emotional distress, an important proxy for

  9. The Link between Knowledge, Attitudes and Practices in Relation to Atmospheric Haze Pollution in Peninsular Malaysia

    Science.gov (United States)

    De Pretto, Laura; Acreman, Stephen; Ashfold, Matthew J.; Mohankumar, Suresh K.; Campos-Arceiz, Ahimsa

    2015-01-01

    Transboundary haze episodes caused by seasonal forest fires have become a recurrent phenomenon in Southeast Asia, with serious environmental, economic, and public health implications. Here we present a cross-sectional survey conducted among people in Kuala Lumpur and surrounds to assess the links between knowledge, attitudes, and practices in relation to the transboundary haze episodes. Of 305 respondents, 125 were amateur athletes participating in a duathlon event and the remainder were surveyed in an inner-city shopping mall. Across the whole sample, people who possessed more factual information about the haze phenomenon showed significantly higher levels of concern. Duathletes were more knowledgeable than non-duathletes and also more concerned about the negative effects of haze, especially on health. For all people who regularly practice outdoor sports (including people interviewed at the shopping mall), higher levels of knowledge and concerned attitudes translated into a greater likelihood of engaging in protective practices, such as cancelling their outdoor training sessions, while those with greater knowledge were more likely to check the relevant air pollution index on a daily basis. Our results indicate that the provision of accurate and timely information about air quality to residents will translate into beneficial practices, at least among particularly exposed individuals, such as amateur athletes who regularly practice outdoor sports. PMID:26646896

  10. Link between Work-Related Prosocial Orientation and Professional Capability of Employees: A Preliminary Exploratory Investigation

    Directory of Open Access Journals (Sweden)

    Małgorzata Adamska-Chudzińska

    2015-05-01

    Full Text Available The paper explores the link between work-related prosocial orientation of organizations and professional capabilities of employees suggesting that the prosocial orientation impacts the level of professional capability and proactive engagement. The article applies three main methods: literature studies, in-depth questionnaire surveys and multi-person method of assessment. The applied sub-measures for both leading constructs were formed and collinearity was tested using linear correlation coefficient. In prosocial environments psychological predispositions as essential aspects of personality and determinants of human behaviour, activate and stimulate professional activity. The implementation of a prosocial orientation leads to significant growth in professional capability and can influence employees’ entrepreneurial behaviour. An important aspect of employee proactive behaviour is building an internal policy based on prosocial mechanisms. Effective stimulation of prosocial and proactive attitudes and actions requires the creation of an environment where activities are realized alongside social values and with respect for individual personal determinants of activity. Considerations and findings presented in the paper contribute to the area of determinants of effective and lasting proactive employee development. The use of the multi-person method can be considered valuable in behavioural research in entrepreneurship.

  11. The Link between Knowledge, Attitudes and Practices in Relation to Atmospheric Haze Pollution in Peninsular Malaysia.

    Directory of Open Access Journals (Sweden)

    Laura De Pretto

    Full Text Available Transboundary haze episodes caused by seasonal forest fires have become a recurrent phenomenon in Southeast Asia, with serious environmental, economic, and public health implications. Here we present a cross-sectional survey conducted among people in Kuala Lumpur and surrounds to assess the links between knowledge, attitudes, and practices in relation to the transboundary haze episodes. Of 305 respondents, 125 were amateur athletes participating in a duathlon event and the remainder were surveyed in an inner-city shopping mall. Across the whole sample, people who possessed more factual information about the haze phenomenon showed significantly higher levels of concern. Duathletes were more knowledgeable than non-duathletes and also more concerned about the negative effects of haze, especially on health. For all people who regularly practice outdoor sports (including people interviewed at the shopping mall, higher levels of knowledge and concerned attitudes translated into a greater likelihood of engaging in protective practices, such as cancelling their outdoor training sessions, while those with greater knowledge were more likely to check the relevant air pollution index on a daily basis. Our results indicate that the provision of accurate and timely information about air quality to residents will translate into beneficial practices, at least among particularly exposed individuals, such as amateur athletes who regularly practice outdoor sports.

  12. The Link between Knowledge, Attitudes and Practices in Relation to Atmospheric Haze Pollution in Peninsular Malaysia.

    Science.gov (United States)

    De Pretto, Laura; Acreman, Stephen; Ashfold, Matthew J; Mohankumar, Suresh K; Campos-Arceiz, Ahimsa

    2015-01-01

    Transboundary haze episodes caused by seasonal forest fires have become a recurrent phenomenon in Southeast Asia, with serious environmental, economic, and public health implications. Here we present a cross-sectional survey conducted among people in Kuala Lumpur and surrounds to assess the links between knowledge, attitudes, and practices in relation to the transboundary haze episodes. Of 305 respondents, 125 were amateur athletes participating in a duathlon event and the remainder were surveyed in an inner-city shopping mall. Across the whole sample, people who possessed more factual information about the haze phenomenon showed significantly higher levels of concern. Duathletes were more knowledgeable than non-duathletes and also more concerned about the negative effects of haze, especially on health. For all people who regularly practice outdoor sports (including people interviewed at the shopping mall), higher levels of knowledge and concerned attitudes translated into a greater likelihood of engaging in protective practices, such as cancelling their outdoor training sessions, while those with greater knowledge were more likely to check the relevant air pollution index on a daily basis. Our results indicate that the provision of accurate and timely information about air quality to residents will translate into beneficial practices, at least among particularly exposed individuals, such as amateur athletes who regularly practice outdoor sports.

  13. National legal system in relation to vulnerable population groups

    Directory of Open Access Journals (Sweden)

    Sjeničić Marta

    2015-01-01

    Full Text Available Vulnerable social groups can be recognized in everyday life, and local legal regulations identify them as well. Strategies and laws clearly identify the increased needs of vulnerable groups. Local legislation, for example, observes comparative law trends and attempts to prevent discrimination of persons with disabilities, emphasizes their human rights and creates the legal framework for taking these persons out of the institutional form of protection and including them into the community. In Serbia however, strategies and laws, as well as by-laws, are written in sectors, and not in cross-sectors manner. Proper caring for persons with disabilities, including persons with mental disabilities, requires an integral approach, namely a mutual approach of the social, health, educational and other sectors. True enough, local regulations stress the need for an intersectional approach, but such an approach is scantily applied in practice, so the comprehensive care that would satisfy the multiple needs of persons with mental disabilities often turns out to be less than expected in the community. Pursuant to national laws and basic ethic principals, all citizens of the Republic of Serbia have the right to health protection without discrimination. Therefore, methods for using health protection, easier than the existing ones, should be found for certain vulnerable groups, depending on their characteristics, and so for the Roma as well, and bearing in mind that systemic health regulations in Serbia open the door to special treatment of these groups. The inaccessible approach to health care of the Roma population persists primarily due to insufficient basic health documentation and basic personal documentation. Personal documents are linked with the registered place of residence, which the Roma, largely do not have. The problem is thus on a wider scale and is not only focused on the health sector. As such, it requires a wider, intersectional approach and a

  14. DIA1R is an X-linked gene related to Deleted In Autism-1.

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    Azhari Aziz

    Full Text Available BACKGROUND: Autism spectrum disorders (ASDS are frequently occurring disorders diagnosed by deficits in three core functional areas: social skills, communication, and behaviours and/or interests. Mental retardation frequently accompanies the most severe forms of ASDs, while overall ASDs are more commonly diagnosed in males. Most ASDs have a genetic origin and one gene recently implicated in the etiology of autism is the Deleted-In-Autism-1 (DIA1 gene. METHODOLOGY/PRINCIPAL FINDINGS: Using a bioinformatics-based approach, we have identified a human gene closely related to DIA1, we term DIA1R (DIA1-Related. While DIA1 is autosomal (chromosome 3, position 3q24, DIA1R localizes to the X chromosome at position Xp11.3 and is known to escape X-inactivation. The gene products are of similar size, with DIA1 encoding 430, and DIA1R 433, residues. At the amino acid level, DIA1 and DIA1R are 62% similar overall (28% identical, and both encode signal peptides for targeting to the secretory pathway. Both genes are ubiquitously expressed, including in fetal and adult brain tissue. CONCLUSIONS/SIGNIFICANCE: Examination of published literature revealed point mutations in DIA1R are associated with X-linked mental retardation (XLMR and DIA1R deletion is associated with syndromes with ASD-like traits and/or XLMR. Together, these results support a model where the DIA1 and DIA1R gene products regulate molecular traffic through the cellular secretory pathway or affect the function of secreted factors, and functional deficits cause disorders with ASD-like symptoms and/or mental retardation.

  15. The rise of global health diplomacy: An interdisciplinary concept linking health and international relations.

    Science.gov (United States)

    Chattu, Vijay Kumar

    2017-01-01

    Global health diplomacy (GHD) is relatively a very new field that has yet to be clearly defined and developed though there are various definitions given by different experts from foreign policy, global health, diplomacy, international relations, governance, and law. With the intensification of globalization and increasing gaps between countries, new and reemerging health threats such as HIV/AIDS, tuberculosis, influenza, severe acute respiratory syndrome, Ebola, and Zika and a gradual rethinking on security concepts framed a new political context. The health problems addressed diplomatically have also become diverse ranging from neglected tropical diseases, infectious diseases, sale of unsafe, counterfeit drugs to brain drain crisis. We see that global health has become more diverse as the actors widened and also the interests appealing not only to the traditional humanitarian ideals associated with health but also to the principles grounded in national and global security. Recently, we are witnessing the increased priority given to the GHD because the issue of health is discussed by various actors outside the WHO to shape the global policy for health determinants. In fact, the area of health has become the part of UN Summit Diplomacy involving the G8, G20, BRICS, and the EU. The recent WHO Pandemic Influenza Framework, UN High Level Framework on Prevention and Control of Noncommunicable Diseases, and the WHO Framework Convention on Tobacco Control are some of the examples of long-term negotiation processes for agreements that took place.

  16. Nuclear energy related capabilities at Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Pickering, Susan Y. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-02-01

    Sandia National Laboratories' technology solutions are depended on to solve national and global threats to peace and freedom. Through science and technology, people, infrastructure, and partnerships, part of Sandia's mission is to meet the national needs in the areas of energy, climate and infrastructure security. Within this mission to ensure clean, abundant, and affordable energy and water is the Nuclear Energy and Fuel Cycle Programs. The Nuclear Energy and Fuel Cycle Programs have a broad range of capabilities, with both physical facilities and intellectual expertise. These resources are brought to bear upon the key scientific and engineering challenges facing the nation and can be made available to address the research needs of others. Sandia can support the safe, secure, reliable, and sustainable use of nuclear power worldwide by incorporating state-of-the-art technologies in safety, security, nonproliferation, transportation, modeling, repository science, and system demonstrations.

  17. Relating Operational Art to the National Guard State Partnership Program

    Science.gov (United States)

    2014-05-15

    Program Coordinator GEF Global Employment of the Force DSCA Defense Support of Civil Authorities BCA Budget Control Act NATO North Atlantic Treaty...between Florida and the U.S. Virgin Islands are referred to as the Regional Security System (RSS). Florida and the U.S. Virgin Islands partner with... Atlantic Treaty Organization (NATO) in 2004 due, in part, to the mentorship from the Maryland National Guard.54 Not only did the Maryland National Guard

  18. Study on the Workspace of a 6-DOF Parallel Topology Robot Related to Binary Link Lengths

    Directory of Open Access Journals (Sweden)

    Calin-Octavian Miclosina

    2016-12-01

    Full Text Available The paper presents a study on the workspace of a parallel topology robot with the structure FP3+6•SPS+MP3. The variable parameters are the binary link lengths, from both upper and lower levels, and the driving kinematical joint strokes. The workspace boundary is determined by SolidWorks software simulations. For different binary link lengths, workspace volume is determined and sections through the workspace are presented.

  19. Water relations link carbon and oxygen isotope discrimination to phloem sap sugar concentration in eucalyptus globulus

    International Nuclear Information System (INIS)

    Cernusak, L.A.; Farquhar, G.D.; Arthur, D.J; Pate, J.S.

    2002-01-01

    Full text: The carbon isotope ratio of phloem sap sugars has been previously observed to correlate strongly with the phloem sap sugar concentration in Eucalyptus globulus. We hypothesized that the correspondence between these two parameters results from co-linearity in their responses to variation in plant water potential. Carbon isotope discrimination is expected to decrease with decreasing plant water potential due to the influence of stomatal conductance on the ratio of intercellular to ambient CO 2 , concentrations (c 1 /c a ). Conversely, we expected the phloem sap sugar concentration to increase with decreasing plant water potential, thereby maintaining positive turgor pressure within the sieve tubes. The study comprised 40 individual Eucalyptus globulus trees growing in three plantations situated on opposing ends of a rainfall gradient in southwestern Australia. A strong correlation was observed between the carbon isotope ratio in phloem sap sugars and phloem sap sugar concentration. Carbon isotope discrimination correlated positively with shoot water potential, whereas phloem sap sugar concentration correlated negatively with shoot water potential. The relationship between carbon isotope discrimination measured in phloem sap sugars collected from the stem and c 1 /c a measured instantaneously on subtending leaves was close to that theoretically predicted. Accordingly, a strong, negative relationship was observed between instantaneous c 1 /c a and the phloem sap sugar concentration. Oxygen isotope discrimination in phloem sap sugars also correlated strongly with phloem sap sugar concentration. A theoretical model suggested that the observed variation in stomatal conductance was sufficient to account for the variation observed in oxygen isotope discrimination across the study. Results strongly support the contention that water relations form a mechanistic link between phloem sap sugar concentration and both instantaneous and integrated measures of the

  20. Monitoring air quality in Southeast Alaska’s National Parks and Forests: Linking atmospheric pollutants with ecological effects

    Science.gov (United States)

    D. Schirokauer; L. Geiser; A. Bytnerowicz; M. Fenn; K. Dillman

    2014-01-01

    Air quality and air quality related values are important resources to the National Park Service (NPS) units and Wilderness areas in northern Southeast Alaska. Air quality monitoring was prioritized as a high-priority Vital Sign at the Southeast Alaska Network’s (SEAN) Inventory and Monitoring Program’s terrestrial scoping workshop (Derr and Fastie 2006). Air quality...

  1. The Coordination Dynamics of Observational Learning: Relative Motion Direction and Relative Phase as Informational Content Linking Action-Perception to Action-Production.

    Science.gov (United States)

    Buchanan, John J

    2016-01-01

    The primary goal of this chapter is to merge together the visual perception perspective of observational learning and the coordination dynamics theory of pattern formation in perception and action. Emphasis is placed on identifying movement features that constrain and inform action-perception and action-production processes. Two sources of visual information are examined, relative motion direction and relative phase. The visual perception perspective states that the topological features of relative motion between limbs and joints remains invariant across an actor's motion and therefore are available for pickup by an observer. Relative phase has been put forth as an informational variable that links perception to action within the coordination dynamics theory. A primary assumption of the coordination dynamics approach is that environmental information is meaningful only in terms of the behavior it modifies. Across a series of single limb tasks and bimanual tasks it is shown that the relative motion and relative phase between limbs and joints is picked up through visual processes and supports observational learning of motor skills. Moreover, internal estimations of motor skill proficiency and competency are linked to the informational content found in relative motion and relative phase. Thus, the chapter links action to perception and vice versa and also links cognitive evaluations to the coordination dynamics that support action-perception and action-production processes.

  2. Comparative Results From a National Joint Registry Hip Data Set of a New Cross-Linked Annealed Polyethylene vs Both Conventional Polyethylene and Ceramic Bearings.

    Science.gov (United States)

    Epinette, Jean-Alain; Jolles-Haeberli, Brigitte M

    2016-07-01

    Major concerns in hip arthroplasty concern the fate of bearing surfaces. Highly cross-linked polyethylene materials (HXLPE) currently demonstrate successful in vitro results with new technical procedures of cross-linking the polyethylene material, whereas processing the polyethylene below its melting temperature to produce so-called "annealed HXLPE" would allow retention of important mechanical properties. Data released by the National Joint Registry of England and Wales addressing in 45,877 hips the same Trident uncemented cup, allowed us to compare the performance of a consecutive cohort of patients implanted with the newest generation of annealed HXLPE acetabular bearings (X3: 21,470) vs 2 consecutive nonselected cohorts, one with conventional polyethylene (N2vac: 8225) and one with ceramic-on-ceramic (CoC) hip bearings (AL: 16,182). The main end point in survivorship has been first defined as revision for any cause, then for any cause which could be related to a failure of the bearing couple. At 6-year follow-up, all Trident cups demonstrated encouraging global survival cumulative rates all between 95% and 99%. A first study demonstrated better survivorship with X3-HXLPE liners vs conventional ultrahigh molecular weight polyethylene. On the second parallel study, the cumulative survival rates were better for X3 liners as compared to CoC bearings. Moreover, when ranking the yearly cumulative percent revision rates, again the best results were obtained with X3 liners with small alumina heads (cumulative percent revision rate at 0.298). Within the frame of this Trident study, the use of this X3 highly cross-linked annealed polyethylene could be considered as a reliable alternate solution to CoC bearings. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. The influence of nationality and playing position on relative age ...

    African Journals Online (AJOL)

    These results suggest that late maturing players have been disproportionately lost to the South African system across all positions. Conclusion: Nation-specific youth sport culture appears to be more important than playing position for determining who is at risk of RAEs in rugby union. Keywords: birth date, team sport, talent ...

  4. Effect of marijuana use on cardiovascular and cerebrovascular mortality: A study using the National Health and Nutrition Examination Survey linked mortality file.

    Science.gov (United States)

    Yankey, Barbara A; Rothenberg, Richard; Strasser, Sheryl; Ramsey-White, Kim; Okosun, Ike S

    2017-11-01

    Background Reports associate marijuana use with cardiovascular emergencies. Studies relating marijuana use to cardiovascular mortality are scarce. Recent advance towards marijuana use legalization emphasizes the importance of understanding relationships between marijuana use and cardiovascular deaths; the primary ranked mortality. Recreational marijuana is primarily smoked; we hypothesize that like cigarette smoking, marijuana use will be associated with increased cardiovascular mortalities. Design The design of this study was based on a mortality follow-up. Method We linked participants aged 20 years and above, who responded to questions on marijuana use during the 2005 US National Health and Nutrition Examination Survey to data from the 2011 public-use linked mortality file of the National Center for Health Statistics, Centers for Disease Control and Prevention. Only participants eligible for mortality follow-up were included. We conducted Cox proportional hazards regression analyses to estimate hazard ratios for hypertension, heart disease, and cerebrovascular mortality due to marijuana use. We controlled for cigarette smoking and other relevant variables. Results Of the 1213 eligible participants 72.5% were presumed to be alive. The total follow-up time was 19,569 person-years. Adjusted hazard ratios for death from hypertension among marijuana users compared to non-marijuana users was 3.42 (95% confidence interval: 1.20-9.79) and for each year of marijuana use was 1.04 (95% confidence interval: 1.00-1.07). Conclusion From our results, marijuana use may increase the risk for hypertension mortality. Increased duration of marijuana use is associated with increased risk of death from hypertension. Recreational marijuana use potentially has cardiovascular adverse effects which needs further investigation.

  5. Reactive and Proactive Subtypes of Relational and Physical Aggression in Middle Childhood: Links to Concurrent and Longitudinal Adjustment

    Science.gov (United States)

    Mathieson, Lindsay C.; Crick, Nicki R.

    2010-01-01

    Peer aggression in children is a serious issue that school psychologists often encounter on a daily basis. To develop a better understanding of aggression, it is important to look at specific subtypes of aggression and how they are related to adjustment difficulties. Past research has examined the links between reactive and proactive physical…

  6. Learning with LinkedIn: Students' Perceptions of Incorporating Subject-Related Blogging in an International Marketing Course

    Science.gov (United States)

    Galan, Nataliya; Khodabandehloo, Akbar

    2016-01-01

    Purpose: This paper aims to report the results of implementation of blogging within a LinkedIn discussion group in an international marketing course for a multicultural group of students focusing on the students' perceptions of the subject-related blogging. Design/Methodology/ Approach: This study adopts a qualitative approach; data have been…

  7. Relational Regulation Theory : A New Approach to Explain the Link Between Perceived Social Support and Mental Health

    NARCIS (Netherlands)

    Lakey, Brian; Orehek, Edward

    Perceived support is consistently linked to good mental health, which is typically explained as resulting from objectively supportive actions that buffer stress. Yet this explanation has difficulty accounting for the often-observed main effects between support and mental health. Relational

  8. The Broader Context of Relational Aggression in Adolescent Romantic Relationships: Predictions from Peer Pressure and Links to Psychosocial Functioning

    Science.gov (United States)

    Schad, Megan M.; Szwedo, David E.; Antonishak, Jill; Hare, Amanda; Allen, Joseph P.

    2008-01-01

    The broader context of relational aggression in adolescent romantic relationships was assessed by considering the ways such aggression emerged from prior experiences of peer pressure and was linked to concurrent difficulties in psychosocial functioning. Longitudinal, multi-reporter data were obtained from 97 adolescents and their best friends at…

  9. Linking habitat selection to fitness-related traits in herbivores: the role of the energy landscape

    Science.gov (United States)

    Ryan A. Long; R. T. Bowyer; Warren P. Porter; Paul Mathewson; Kevin L. Monteith; Scott L. Findholt; Brian L. Dick; John G. Kie

    2016-01-01

    Animals may partially overcome environmental constraints on fitness by behaviorally adjusting their exposure to costs and supplies of energy. Few studies, however, have linked spatiotemporal variation in the energy landscape to behaviorally mediated measures of performance that ostensibly influence individual fitness. We hypothesized that strength of selection by North...

  10. Legal questions relating to nuclear installations close to national frontiers

    International Nuclear Information System (INIS)

    Zieger, G.

    1983-01-01

    Main emphasis is placed on the criteria to decide whether the construction and operation of a nulcear power plant close to a national frontier is permissible or not. The author discusses the relevant provisions of the international law and those of the Treaty of Rome pertaining to the settlement of conflicts between neighbour states. According to the opinion of the author, nuclear installations close to borders are incompatible with international law only if they do not comply with accepted safety standards. The international agreements do not prohibit the construction of nuclear installations close to frontiers. It would be desirable, however, the author says, to conclude international treaties providing for mutual consultation and information, thus offering a platform for discussing controversial national interests; this idea already being put into practice in customary international law. (WB) [de

  11. Monitoring selected conditions related to wilderness character: a national framework

    Science.gov (United States)

    Peter Landres; Steve Boutcher; Linda Merigliano; Chris Barns; Denis Davis; Troy Hall; Steve Henry; Brad Hunter; Patrice Janiga; Mark Laker; Al McPherson; Douglas S. Powell; Mike Rowan; Susan Sater

    2005-01-01

    One of the central mandates of the 1964 Wilderness Act is that “each agency administering any area designated as wilderness shall be responsible for preserving the wilderness character of the area.” Although wilderness comprises about 20 percent of National Forest System lands (over 35 million acres), the agency lacks a way to evaluate progress in fulfilling this...

  12. Viruses as the causative agent related to 'dampness' and the missing link between allergen exposure and onset of allergic disease

    DEFF Research Database (Denmark)

    Hersoug, Lars-Georg

    2005-01-01

    concentration and symptoms indicate a missing link between allergen exposure and onset of asthma. Respiratory viruses have been identified in up to 85% cases of asthma or exacerbations of asthma. The missing link between respiratory diseases and humid indoor climates could therefore be attributed to viruses....... The infectious effectiveness of respiratory viruses depends strongly on the environment where the viruses are spread. For respiratory viruses, survival and infectivity are dependent on temperature and relative humidity. A direct link between virus-induced inflammation and the asthmatogenic process has been...... subjects. Therefore, a humid indoor climate could also represent a higher risk for persons already sensitized to one or more allergens. PRACTICAL IMPLICATIONS: In epidemiological studies where the relationship between moisture in the indoor climate, respiratory symptoms and exposure to allergens...

  13. An Overview of National Trends Related to Innovative Ventilation Systems

    DEFF Research Database (Denmark)

    Heijmans, Nicolas; Wouters, Peter; Heiselberg, Per

    2008-01-01

    This paper summarises the discussion related to innovative (ventilation) systems that took place at the AIVC workshop organised in Ghent, Belgium, in March 2008.......This paper summarises the discussion related to innovative (ventilation) systems that took place at the AIVC workshop organised in Ghent, Belgium, in March 2008....

  14. Developmental Links Between Children's Working Memory and their Social Relations with Teachers and Peers in the Early School Years.

    Science.gov (United States)

    de Wilde, Amber; Koot, Hans M; van Lier, Pol A C

    2016-01-01

    This study assessed the developmental links between children's working memory development and their relations with teachers and peers across 2 years of kindergarten and early elementary school. Kindergarten and first grade children, N = 1109, 50% boys, were followed across 2 school-years. Children were assessed across 3 waves, in the fall and spring of the first school-year (within school-year), and finally in the spring of the second school-year. Working memory was assessed using a visuo-spatial working memory task. The developmental links between working memory and child-reported teacher-child relationship quality (warmth and conflict) and peer-nominated likeability and friendedness were assessed using autoregressive cross-lagged models. Lower working memory scores were related to increases in teacher-child conflict and decreases in teacher-child warmth one school-year later, in addition to decreases in likeability by peers within the same school-year. Conversely, teacher-child conflict was negatively associated with the development of working memory across the studied period. Path estimates between working memory and social relational factors were similar for boys and girls. Findings show developmental links between working memory and social-relational factors and vice versa. These results suggest that children's working memory development can be fostered through pro-social relations with teachers in early elementary school children.

  15. Suspected X-linked facial dysmorphia and growth retardation in related Labrador retriever puppies.

    Science.gov (United States)

    Dierks, C; Hoffmann, H; Heinrich, F; Hellige, M; Hewicker-Trautwein, M; Distl, O

    2017-02-01

    Seven male Labrador retriever puppies from four different litters were identified with a brachycephalic-like face and skull, associated with low birth weight, severe growth retardation, and reduced abilities to crawl and suckle, which were not compatible with survival. Excessive doming of the cranium, brachygnathia superior and inferior, and an abnormally opened fontanelle were found in all affected puppies by computed tomography and at post-mortem examination. Pedigree analysis supported an X-linked recessive mode of inheritance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. The influence of nationality and playing position on relative age ...

    African Journals Online (AJOL)

    Kathryn van Boom

    for this phenomenon, termed the relative age effect (RAE), is that children born in the ... of countries have introduced modified games or weight categories in some ... A review of an online database (http://www.itsrugby.co.uk/) revealed the names ... positive SR indicated a higher than expected number of births in that quarter.

  17. Strengthening health-related rehabilitation services at national levels.

    Science.gov (United States)

    Gutenbrunner, Christoph; Bickenbach, Jerome; Melvin, John; Lains, Jorge; Nugraha, Boya

    2018-04-18

    One of the aims of the World Health Organization's Global Disability Action Plan is to strengthen rehabilitation services. Some countries have requested support to develop (scale-up) rehabilitation services. This paper describes the measures required and how (advisory) missions can support this purpose, with the aim of developing National Disability, Health and Rehabilitation Plans. It is important to clarify the involvement of governments in the mission, to define clear terms of reference, and to use a systematic pathway for situation assessment. Information must be collected regarding policies, health, disability, rehabilitation, social security systems, the need for rehabilitation, and the existing rehabilitation services and workforce. Site visits and stakeholder dialogues must be done. In order to develop a Rehabilitation Service Implementation Framework, existing rehabilitation services, workforce, and models for service implementation and development of rehabilitation professions are described. Governance, political will and a common understanding of disability and rehabilitation are crucial for implementation of the process. The recommendations of the World Report on Disability are used for reporting purposes. This concept is feasible, and leads to concrete recommendations and proposals for projects and a high level of consensus stakeholders.

  18. Strengthening health-related rehabilitation services at national levels

    Directory of Open Access Journals (Sweden)

    Christoph Gutenbrunner

    2017-04-01

    Full Text Available Objective: One of the aims of the World Health Organization’s Global Disability Action Plan is to strengthen rehabilitation services. Some countries have requested support to develop (scale-up rehabilitation services. This paper describes the measures required and how (advisory missions can support this purpose, with the aim of developing National Disability, Health and Rehabilitation Plans. Recommendations: It is important to clarify the involvement of governments in the mission, to define clear terms of reference, and to use a systematic pathway for situation assessment. Information must be collected regarding policies, health, disability, rehabilitation, social security systems, the need for rehabilitation, and the existing rehabilitation services and workforce. Site visits and stakeholder dialogues must be done. In order to develop a Rehabilitation Service Implementation Framework, existing rehabilitation services, workforce, and models for service implementation and development of rehabilitation professions are described. Governance, political will and a common understanding of disability and rehabilitation are crucial for implementation of the process. The recommendations of the World Report on Disability are used for reporting purposes. Conclusion: This concept is feasible, and leads to concrete recommendations and proposals for projects and a high level of consensus stakeholders.

  19. Adolescents' and mothers' conflict management constellations: Links with individual and relational functioning

    NARCIS (Netherlands)

    Missotten, L.; Luyckx, Koen; Vanhalst, J.; Nelemans, S.A.; Branje, S.J.T.

    2017-01-01

    In the present multi-informant study, we examined dyadic combinations of adolescent and maternal conflict management styles through stepwise latent class analysis. We investigated how these dyadic conflict classes related to adolescents' and mothers' perceptions of individual and relational

  20. 77 FR 25868 - Notification of Employee Rights Under the National Labor Relations Act

    Science.gov (United States)

    2012-05-02

    ..., 2011.) On October 12, 2011, the Board amended that rule to delay the effective date from November 14... announce that delay in the effective date of the rule. DATES: The effective date of the final rule... the National Labor Relations Act AGENCY: National Labor Relations Board. ACTION: Final rule; Court...

  1. 76 FR 82133 - Notification of Employee Rights Under the National Labor Relations Act

    Science.gov (United States)

    2011-12-30

    ... the National Labor Relations Act AGENCY: National Labor Relations Board. ACTION: Final rule; delay of....) The Board hereby further amends that rule to delay the effective date from January 31, 2012, to April... rule requiring employers, including labor organizations in their capacity as employers, subject to the...

  2. 76 FR 63188 - Notification of Employee Rights Under the National Labor Relations Act

    Science.gov (United States)

    2011-10-12

    ... the National Labor Relations Act AGENCY: National Labor Relations Board. ACTION: Final rule; delay of... rule requiring employers, including labor organizations in their capacity as employers, subject to the... under the NLRA. The Board hereby amends that rule to change the effective date from November 14, 2011...

  3. Direct and indirect links between parenting styles, self-concealment (secrets), impaired control over drinking and alcohol-related outcomes.

    Science.gov (United States)

    Hartman, Jessica D; Patock-Peckham, Julie A; Corbin, William R; Gates, Jonathan R; Leeman, Robert F; Luk, Jeremy W; King, Kevin M

    2015-01-01

    Self-concealment reflects uncomfortable feelings, thoughts, and information people have about themselves that they avoid telling others (Larson & Chastain, 1990). According to Larson and Chastain (1990) these secrets range from the slightly embarrassing to the very distressing with an individual's most traumatic experiences often concealed. Parental attitudes including those involving self-disclosure are thought to be expressed in their choice of parenting style (Brand, Hatzinger, Beck, & Holsboer-Trachsler, 2009). The specific aim of this investigation was to examine the direct and indirect influences of parenting styles on self-concealment, impaired control over drinking (i.e. the inability to stop drinking when intended), alcohol use (quantity/frequency), and alcohol-related problems. A structural equation model with 419 (223 men, 196 women) university students was examined. Two and three path mediated effects were examined with the bias corrected bootstrap technique in Mplus. Having an authoritarian mother was directly linked to more self-concealment, while having an authoritative father was directly linked to less self-concealment. Higher levels of mother authoritarianism were indirectly linked to both increased alcohol use and alcohol-related problems through more self-concealment and more impaired control over drinking. Moreover, higher levels of father authoritativeness were indirectly linked to less alcohol use and alcohol-related problems through less self-concealment and less impaired control over drinking. These findings suggest that parenting styles influence vulnerabilities such as self-concealment in the impaired control over the drinking pathway to alcohol use and alcohol-related problems. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Investigation and Analysis on the Construction Situation of “Three Links and Two Platforms” of Education for Nationalities in Yunnan Province in China

    Directory of Open Access Journals (Sweden)

    Zhilin Zhao

    2017-01-01

    Full Text Available “Three Links and Two Platforms”, which refers to schools links to ICTs, high-quality resource of class links to ICTs, people links to ICTs, public service platform for educational resources and public service platform for educational management, has played a crucial role in improving the educational equality in minority areas in Yunnan province and in realizing the sharing of high-quality educational resources. This research mainly adopts method of document investigation, which has investigated the construction situation of “Three Links and Two Platforms” in eight ethnic autonomous prefectures in Yunnan province in China including Chuxiong Yi Nationality Autonomous Prefecture, etc. The results show that the average value of the construction of “Three Links” is 63.55%n 14.75% and 9.00% respectively. “Two Platforms” mainly focus on public service platform for educational resources and public service platform for the construction of educational statistics, and the informatization of national education in Yunnan province should be improved greatly.

  5. The Work–Home Interface : Linking Work-Related Wellbeing and Volunteer Work

    OpenAIRE

    Brauchli, Rebecca; Peeters, Maria C W; van Steenbergen, Elianne F.; Wehner, Theo; Hämmig, Oliver

    2017-01-01

    An abundance of research shows the benefits of participation in volunteer work for individuals, employers and the society as a whole. However, relatively little is known about the precursors of volunteer work. In this study, we aim to fill this gap by investigating to what extent work-related well-being can function as a driver of volunteer work. Moreover, building on the Conservations of Resources Theory (Hobfoll,), we propose that the relationship between work-related well-being (burnout an...

  6. Presidential Elections and HIV-Related National Policies and Programs.

    Science.gov (United States)

    Holtgrave, David R; Bonacci, Robert A; Valdiserri, Ronald O

    2017-03-01

    The November 2016 general election and subsequent voting of the Electoral College resulted in the selection of Donald Trump as President of the United States. The incoming Administration ran a campaign that indicated a desire for substantial change in health policy, including the repeal of the Affordable Care Act (ACA). President Trump has said very little directly about HIV programs and policies, but some campaign positions (such as the repeal of the ACA) would clearly and substantially impact the lives of persons living with HIV. In this editorial, we highlight important HIV-related goals to which we must recommit ourselves, and we underscore several key points about evidence-based advocacy that are important to revisit at any time (but most especially when there is a change in Administration).

  7. Hypertension prevalence and living conditions related to air pollution: results of a national epidemiological study in Lebanon.

    Science.gov (United States)

    Salameh, Pascale; Chahine, Mirna; Hallit, Souheil; Farah, Rita; Zeidan, Rouba Karen; Asmar, Roland; Hosseiny, Hassan

    2018-04-01

    Hypertension is a risk factor of several diseases, linked to high mortality and morbidity, particularly in developing countries. Some studies have linked indoor and outdoor pollution exposure items to hypertension, but results were inconsistent. Our objective was to assess the association of living conditions related to air pollution to hypertension in Lebanon, a Middle Eastern country. A national cross-sectional study was conducted all over Lebanon. Blood pressure and its related medications were assessed to be able to classify participants as hypertensive or not. Moreover, in addition to living conditions related to air pollution exposure, we assessed potential predictors of hypertension, including sociodemographic characteristics, self-reported health information and biological measurements. Furthermore, we assessed dose-effect relationship of air pollution items in relation with hypertension. Living conditions related to indoor and outdoor air pollution exposures were associated with hypertension, with or without taking biological values into account. Moreover, we found a dose-effect relationship of exposure with risk of disease (15% increase in risk of disease for every additional pollution exposure item), after adjustment for sociodemographics and biological characteristics (Ora = 1.15 [1.03-1.28]). Although additional studies would be necessary to confirm these findings, interventions should start to sensitize the population about the effect of air pollution on chronic diseases. The work on reducing pollution and improving air quality should be implemented to decrease the disease burden on the population and health system.

  8. Gambling and physical intimate partner violence: Results from the national epidemiologic survey on alcohol and related conditions (NESARC).

    Science.gov (United States)

    Roberts, Amanda; Landon, Jason; Sharman, Stephen; Hakes, Jahn; Suomi, Aino; Cowlishaw, Sean

    2018-01-01

    Links between intimate partner violence (IPV) and gambling problems are under researched in general population samples. Understanding these relationships will allow for improved identification and intervention. We investigated these relationships and sought to determine whether links were attenuated by axis I and II disorders. This study examined data from waves 1 and 2 (N = 25,631) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC); a nationally representative survey of U.S. adults. Gambling symptoms and other psychiatric disorders were measured at wave 1 by the Alcohol Use Disorder and Associated Disability Interview Schedule-DSM-IV Version (AUDADIS-IV). Physical IPV victimization and perpetration in the last 12 months were assessed 3 years later at wave 2 using items from the Conflict Tactics Scale-R. Binary logistic regression models were used to examine associations separately for males and females. Problem gambling was associated with increased odds of both IPV perpetration for males (OR = 2.62, 95%CI = 1.22-5.60) and females (OR = 2.87, 95%CI = 1.29-6.42), and with IPV victimization for females only (OR = 2.97, 95%CI = 1.31-6.74). Results were attenuated with inclusion of axis I and axis II disorders; links between gambling and IPV were weaker than those involving other mental health conditions. There are prospective associations with gambling problems and physical IPV which have implications for identification, spontaneous disclosure, and treatment seeking. The links between gambling problems and violence are complex and should not be considered independently of co-occurring mental health and substance use disorders. (Am J Addict 2018;27:7-14). © 2017 American Academy of Addiction Psychiatry.

  9. National labour relations in internationalized markets : a comparative study of institutions, change, and performance

    NARCIS (Netherlands)

    Traxler, F.; Blaschke, S.; Kittel, B.E.A.

    2001-01-01

    Presents and examines evidence and theories about changing patterns of industrial relations and their links to convergence on the one hand, and economic competitiveness on the other. Includes a comprehensive set of comparable date on industrial relations in twenty OECD countries including Australia,

  10. Dark personality traits and impulsivity among adolescents : Differential links to problem behaviors and family relations

    NARCIS (Netherlands)

    Dubas, Judith Semon; Baams, Laura; Doornwaard, Suzan M.; van Aken, Marcel A.G.

    2017-01-01

    Research on how dark personality traits develop and relate to risky behaviors and family relations during adolescence is scarce. This study used a person-oriented approach to examine (a) whether distinct groups of adolescents could be identified based on their developmental profiles of

  11. The Work–Home Interface : Linking Work-Related Wellbeing and Volunteer Work

    NARCIS (Netherlands)

    Brauchli, Rebecca; Peeters, Maria C W; van Steenbergen, Elianne F.; Wehner, Theo; Hämmig, Oliver

    2017-01-01

    An abundance of research shows the benefits of participation in volunteer work for individuals, employers and the society as a whole. However, relatively little is known about the precursors of volunteer work. In this study, we aim to fill this gap by investigating to what extent work-related

  12. Relational Aggression in Peer and Dating Relationships: Links to Psychological and Behavioral Adjustment

    Science.gov (United States)

    Ellis, Wendy E.; Crooks, Claire V.; Wolfe, David A.

    2009-01-01

    We examined the contribution of relational aggression in adolescents' peer and dating relationships to their psychological and behavioral adjustment. In the Fall and again four months later, 1279 (646 female) grade 9 students reported on relational aggression perpetration and victimization in their romantic and peer relationships,…

  13. Decay of Iconic Memory Traces Is Related to Psychometric Intelligence: A Fixed-Links Modeling Approach

    Science.gov (United States)

    Miller, Robert; Rammsayer, Thomas H.; Schweizer, Karl; Troche, Stefan J.

    2010-01-01

    Several memory processes have been examined regarding their relation to psychometric intelligence with the exception of sensory memory. This study examined the relation between decay of iconic memory traces, measured with a partial-report task, and psychometric intelligence, assessed with the Berlin Intelligence Structure test, in 111…

  14. Reading-Related Causal Attributions for Success and Failure: Dynamic Links With Reading Skill.

    Science.gov (United States)

    Frijters, Jan C; Tsujimoto, Kimberley C; Boada, Richard; Gottwald, Stephanie; Hill, Dina; Jacobson, Lisa A; Lovett, Maureen W; Mahone, E Mark; Willcutt, Erik G; Wolf, Maryanne; Bosson-Heenan, Joan; Gruen, Jeffrey R

    2018-01-01

    The present study investigated the relation among reading skills and attributions, naming speed, and phonological awareness across a wide range of reading skill. Participants were 1,105 school-age children and youths from two understudied populations: African Americans and Hispanic Americans. Individual assessments of children ranging in age from 8 to 15 years were conducted for reading outcomes, cognitive and linguistic predictors of reading, and attributions for success and failure in reading situations. Quantile regressions were formulated to estimate these relations across the full skill span of each outcome. Reading-related attributions predicted contextual word recognition, sight word and decoding fluency, and comprehension skills. Attributions to ability in success situations were positively related to each outcome across the full span. On three reading outcomes, this relation strengthened at higher skill levels. Attributions to effort in success situations were consistently and negatively related to all reading outcomes. The results provide evidence that the strength of the relation between reading and attributions varies according to reading skill levels, with the strongest evidence for ability-based attributions in situations of reading success.

  15. Dolichol related intermediates involved in N-linked gloycoprotein synthesis in Drosophila Kc cells

    International Nuclear Information System (INIS)

    Sagami, H.; Chap, R.; Rivero, M.; Lennarz, W.J.

    1986-01-01

    The purpose of this investigation is to study the regulation of the biosynthesis of dolichyl phosphate (Dol-P) in embryonic cells. Using embryonic Drosophila Kc cells which are known to lack the squalene-cholesterol branch of polyisoprenoid biosynthetic pathway, the authors labeled the cells in suspension culture for 4 hrs with [5- 3 H]mevalonic acid. After harvesting the cells, the incorporated radioactive lipids were extracted with CHCl 3 /CH 3 OH (2/1). Analysis of the extract by a combination of several methods consisting of ion exchange chromatography on DEAE-cellulose, gel filtration on Fractogel TSK-HW 40, and silica gel thin layer chromatography revealed that the extract contained coenzyme Q, farnesol, dolichol (Dol), Dol-P, and dolichol-linked sugar (Dol-P-Sugar). In a pulse-chase experiment the metabolism of these intermediates was measured for various times up to 30 hrs. The amount of radioactivity in Dol slightly increased with the chase time, while that in Dol-P decreased. The amount of radioactive Dol-P-Sugar remained unchanged. These results suggest that the de novo end product in dolichol biosynthesis is Dol-P and that the level of Dol-P can be controlled by varying the rate of de novo biosynthesis and by dephosphorylation. The authors are now investigating the effect of ecdysone, the molting hormone, on the level of these intermediates and on incorporation of sugars into glycoproteins

  16. 75 FR 8791 - Continuation of the National Emergency Relating to Cuba and of the Emergency Authority Relating...

    Science.gov (United States)

    2010-02-25

    ... to Cuba and of the Emergency Authority Relating to the Regulation of the Anchorage and Movement of... February 23, 2010 Continuation of the National Emergency Relating to Cuba and of the Emergency Authority....-registered civilian aircraft in international airspace north of Cuba. On February 26, 2004, by Proclamation...

  17. Framing Mechanisms Linking HIV-Related Stigma, Adherence to Treatment, and Health Outcomes

    Science.gov (United States)

    Hatcher, Abigail M.; Weiser, Sheri D.; Johnson, Mallory O.; Rice, Whitney S.; Turan, Janet M.

    2017-01-01

    We present a conceptual framework that highlights how unique dimensions of individual-level HIV-related stigma (perceived community stigma, experienced stigma, internalized stigma, and anticipated stigma) might differently affect the health of those living with HIV. HIV-related stigma is recognized as a barrier to both HIV prevention and engagement in HIV care, but little is known about the mechanisms through which stigma leads to worse health behaviors or outcomes. Our conceptual framework posits that, in the context of intersectional and structural stigmas, individual-level dimensions of HIV-related stigma operate through interpersonal factors, mental health, psychological resources, and biological stress pathways. A conceptual framework that encompasses recent advances in stigma science can inform future research and interventions aiming to address stigma as a driver of HIV-related health. PMID:28426316

  18. Links between human LINE-1 retrotransposons and hepatitis virus-related hepatocellular carcinoma

    Science.gov (United States)

    Honda, Tomoyuki

    2016-05-01

    Hepatocellular carcinoma (HCC) accounts for approximately 80% of liver cancers, the third most frequent cause of cancer mortality. The most prevalent risk factors for HCC are infections by hepatitis B or hepatitis C virus. Findings suggest that hepatitis virus-related HCC might be a cancer in which LINE-1 retrotransposons, often termed L1, activity plays a potential role. Firstly, hepatitis viruses can suppress host defense factors that also control L1 mobilization. Secondly, many recent studies also have indicated that hypomethylation of L1 affects the prognosis of HCC patients. Thirdly, endogenous L1 retrotransposition was demonstrated to activate oncogenic pathways in HCC. Fourthly, several L1 chimeric transcripts with host or viral genes are found in hepatitis virus-related HCC. Such lines of evidence suggest a linkage between L1 retrotransposons and hepatitis virus-related HCC. Here, I briefly summarize current understandings of the association between hepatitis virus-related HCC and L1. Then, I discuss potential mechanisms of how hepatitis viruses drive the development of HCC via L1 retrotransposons. An increased understanding of the contribution of L1 to hepatitis virus-related HCC may provide unique insights related to the development of novel therapeutics for this disease.

  19. Flight deck human factors issues for National Airspace System (NAS) en route controller pilot data link communications (CPDLC)

    Science.gov (United States)

    2017-05-01

    Fundamental differences exist between transmissions of Air Traffic Control clearances over voice and those transmitted via Controller Pilot Data Link Communications (CPDLC). This paper provides flight deck human factors issues that apply to processin...

  20. Current-phase relation of a Bose-Einstein condensate flowing through a weak link

    International Nuclear Information System (INIS)

    Piazza, F.; Smerzi, A.; Collins, L. A.

    2010-01-01

    We study the current-phase relation of a Bose-Einstein condensate flowing through a repulsive square barrier by solving analytically the one-dimensional Gross-Pitaevskii equation. The barrier height and width fix the current-phase relation j(δφ), which tends to j∼cos(δφ/2) for weak barriers and to the Josephson sinusoidal relation j∼sin(δφ) for strong barriers. Between these two limits, the current-phase relation depends on the barrier width. In particular, for wide-enough barriers, we observe two families of multivalued current-phase relations. Diagrams belonging to the first family, already known in the literature, can have two different positive values of the current at the same phase difference. The second family, new to our knowledge, can instead allow for three different positive currents still corresponding to the same phase difference. Finally, we show that the multivalued behavior arises from the competition between hydrodynamic and nonlinear-dispersive components of the flow, the latter due to the presence of a soliton inside the barrier region.

  1. Sexual orientation of trans adults is not linked to outcome of transition-related health care, but worth asking.

    Science.gov (United States)

    Nieder, Timo O; Elaut, Els; Richards, Christina; Dekker, Arne

    2016-01-01

    Since the beginning of contemporary transition-related care at the outset of the 20th century, sexual orientation has ben considered to be closely connected with gender identity and the developmental trajectories of trans people. Specifically, health professionals have regarded the anticipated post-transitional heterosexual behaviour of trans adults as predictive of a good outcome of cross-sex hormones and gender-confirming surgeries. This article reviews the current literature according to the question of whether the sexual orientation of trans people is linked to outcome measures following transition-related interventions. A comprehensive review was undertaken using the Medline database, searching for empirical studies published between 2010 and 2015. Out of a total of 474 studies, only 10 studies reported a follow-up of trans adults and assessed sexual orientation in the study protocol at all. Sexual orientation was predominantly assessed as homosexual versus non-homosexual related to sex assigned at birth. Only one 1 of 10 follow-up studies found a significant association according to the outcome between groups differentiated by sexual orientation. Empirically there is no link between sexual orientation and outcome of transition-related health care for trans adults. In order to provide comprehensive health care, we recommend asking for sexual behaviours, attractions and identities, as well as for gender experiences and expressions; however, this knowledge should not drive, but simply inform, such comprehensive care.

  2. Evolution of Interethnic Relations and National Policy in USSR in 1920s − 1991

    Directory of Open Access Journals (Sweden)

    Владимир Матвеевич Козьменко

    2012-06-01

    Full Text Available The article is dedicated to the main stages of the international relations evolution from the first days of the USSR existence to its collapse in 1991. The authors pay attention to the serious mistakes in the national policy of the Communist Party and the Soviet Government that led to the aggravation of the national situation in the USSR and finally to the national and state crisis in the Soviet Union.

  3. The User Interface: A Hypertext Model Linking Art Objects and Related Information.

    Science.gov (United States)

    Moline, Judi

    This report presents a model combining the emerging technologies of hypertext and expert systems. Hypertext is relatively unexplored but promises an innovative approach to information retrieval. In contrast, expert systems have been used experimentally in many different application areas ranging from medical diagnosis to oil exploration. The…

  4. Linking Shared Organisational Context and Relational Capital through Unlearning: An Initial Empirical Investigation in SMEs

    Science.gov (United States)

    Cegarra-Navarro, Juan G.; Dewhurst, Frank W.

    2006-01-01

    Purpose: The environment provided by an organisation to facilitate learning and create knowledge has been defined as the shared organisational context. The value to an organisation of knowledge created by the shared organisational context is called intellectual capital, of which one key component is relational capital. The purpose of this paper is…

  5. Influence of relative humidity on radiosensitivity of Aspergillus flavus Link. infecting cocoa beans

    International Nuclear Information System (INIS)

    Amoako-Atta, B.; Odamtten, G.T.; Appiah, V.

    1981-01-01

    The first part of this paper deals with the moisture sorption isotherms of dried cocoa beans under different relative humidities of 55, 65, 75, 85 or 95%. The second part evaluates the effects of relative humidity (RH), initial moisture content (m.c.) of cocoa beans, and different radiation exposure doses (0, 250, 350, 450, 500 or 550 krad) on Aspergillus flavus spore inoculated cocoa beans kept in fixed RH environmental chamber of 75 or 85% RH post-irradiation for forty days. The results discussed suggest that the m.c. of beans increased from an initial level of 6.4% to 7, 7.8 and 8.9% at 55, 65, and 75% respectively, after a storage period of 6-8 days. However, beans stored under 85% or 95% RH continued to absorb moisture from their respective environments indefinitely during the 64-day storage period. Furthermore, the ambient relative humidity to which the beans are subjected before or after irradiation significantly affect the radiosensitivity of toxigenic A. flavus; the differences in such radiosensitivity are influenced by either the available moisture or the initial m.c. of the beans to the inoculum. The authors conclude from their study that high environmental RH increased the radio-resistance of A. flavus spores making it difficult to establish a radiation decontamination level of practical value under a tropical environment with high ambient relative humidity. (author)

  6. Linking functional and relational service quality to customer satisfaction and loyalty: differences between men and women.

    Science.gov (United States)

    Sánchez-Hernández, Rosa M; Martínez-Tur, Vicente; Peiró, José M; Moliner, Carolina

    2010-04-01

    This study assessed differences between men and women in the association of perceptions of service quality with customer evaluations. Functional (efficiency with which the service is delivered) and relational (customers' emotional benefits, beyond the core performance, related to the social interaction of customers with employees) dimensions of service quality were measured as well as customer satisfaction and loyalty. The sample of 277 customers (191 men, 86 women), surveyed in 29 Mexican hotels, had a mean age of 38.1 yr. (SD=9.7) for men and 34.5 yr. (SD=11.0) for women. To be eligible for survey, customers had to have spent at least one night in the hotel in question. Analysis indicated that the women and men differed in the association of functional and relational dimensions of service quality with their satisfaction and loyalty. Functional service quality was higher for the men than the women, while relational service quality showed greater predictive power for women than for men, although these accounted for only 4% of the customers' satisfaction variance and 6% of the loyalty variance.

  7. Reading-Related Causal Attributions for Success and Failure: Dynamic Links with Reading Skill

    Science.gov (United States)

    Frijters, Jan C.; Tsujimoto, Kimberley C.; Boada, Richard; Gottwald, Stephanie; Hill, Dina; Jacobson, Lisa A.; Lovett, Maureen W.; Mahone, E. Mark; Willcutt, Erik G.; Wolf, Maryanne; Bosson-Heenan, Joan; Gruen, Jeffrey R.

    2018-01-01

    The present study investigated the relation among reading skills and attributions, naming speed, and phonological awareness across a wide range of reading skill. Participants were 1,105 school-age children and youths from two understudied populations: African Americans and Hispanic Americans. Individual assessments of children ranging in age from…

  8. Longitudinal Pathways Linking Child Maltreatment, Emotion Regulation, Peer Relations, and Psychopathology

    Science.gov (United States)

    Kim, Jungmeen; Cicchetti, Dante

    2010-01-01

    Background: The aim of this study was to investigate longitudinal relations among child maltreatment, emotion regulation, peer acceptance and rejection, and psychopathology. Methods: Data were collected on 215 maltreated and 206 nonmaltreated children (ages 6-12 years) from low-income families. Children were evaluated by camp counselors on emotion…

  9. Early estimation of pandemic influenza Antiviral and Vaccine Effectiveness (EAVE): use of a unique community and laboratory national data-linked cohort study.

    Science.gov (United States)

    Simpson, Colin R; Lone, Nazir; McMenamin, Jim; Gunson, Rory; Robertson, Chris; Ritchie, Lewis D; Sheikh, Aziz

    2015-10-01

    After the introduction of any new pandemic influenza, population-level surveillance and rapid assessment of the effectiveness of a new vaccination will be required to ensure that it is targeted to those at increased risk of serious illness or death from influenza. We aimed to build a pandemic influenza reporting platform that will determine, once a new pandemic is under way: the uptake and effectiveness of any new pandemic vaccine or any protective effect conferred by antiviral drugs once available; the clinical attack rate of pandemic influenza; and the existence of protection provided by previous exposure to, and vaccination from, A/H1N1 pandemic or seasonal influenza/identification of susceptible groups. An observational cohort and test-negative study design will be used (post pandemic). A national linkage of patient-level general practice data from 41 Practice Team Information general practices, hospitalisation and death certification, virological swab and serology-linked data. We will study a nationally representative sample of the Scottish population comprising 300,000 patients. Confirmation of influenza using reverse transcription polymerase chain reaction and, in a subset of the population, serology. Future available pandemic influenza vaccination and antivirals will be evaluated. To build a reporting platform tailored towards the evaluation of pandemic influenza vaccination. This system will rapidly measure vaccine effectiveness (VE), adjusting for confounders, estimated by determining laboratory-confirmed influenza; influenza-related morbidity and mortality, including general practice influenza-like illnesses (ILIs); and hospitalisation and death from influenza and pneumonia. Once a validated haemagglutination inhibition assay has been developed (and prior to the introduction of any vaccination), cross-reactivity with previous exposure to A/H1N1 or A/H1N1 vaccination, other pandemic influenza or other seasonal influenza vaccination or exposure will be

  10. 78 FR 9420 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-02-08

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-WASO-NRNHL-12128; 2200-3200-665] National Register of Historic Places; Notification of Pending Nominations and Related Actions Nominations for the... Bacon--Harding Farm, (Cobblestone Architecture of New York State MPS), 3077 Oak Orchard Rd., Gaines...

  11. 77 FR 1722 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-01-11

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-WASO-NRNHL-1212-9138; 2200-3200-665] National Register of Historic Places; Notification of Pending Nominations and Related Actions Nominations... and Architecture MPS) 318 S. Houston Ave., Russellville, 11001049 Pulaski County Capitol--Main...

  12. Linking public relations processes and organizational effectiveness at a state health department.

    Science.gov (United States)

    Wise, Kurt

    2003-01-01

    This qualitative case study explored a state health department's relationships with strategic constituencies from a public relations perspective. The relationships were explored within the theoretical framework of the Excellence Theory, the dominant paradigm in public research. Findings indicate application of the Excellence Theory has the potential to increase organizational effectiveness at public health entities. With respect to the case investigated, findings indicate that the state health department could increase its organizational effectiveness through the adoption of recommendations based on the Excellence Theory.

  13. Dark personality traits and impulsivity among adolescents: Differential links to problem behaviors and family relations.

    Science.gov (United States)

    Dubas, Judith Semon; Baams, Laura; Doornwaard, Suzan M; van Aken, Marcel A G

    2017-10-01

    Research on how dark personality traits develop and relate to risky behaviors and family relations during adolescence is scarce. This study used a person-oriented approach to examine (a) whether distinct groups of adolescents could be identified based on their developmental profiles of callous-unemotional (CU), grandiose manipulative (GM), and dysfunctional impulsivity (DI) traits and (b) whether these groups differ in their problem behaviors and parent-adolescent relationship quality. Latent class growth analyses on 4-wave data of 1,131 Dutch adolescents revealed 3 personality profiles: (1) a dark impulsive group (13.9%), with high scores on all 3 traits (CU, GM, and DI) that were stable over time; (2) an impulsive group (26.1%), with high and increasing levels of impulsivity and relatively low scores on CU and GM; and (3) and a low risk group (60.0%), with relatively low levels on all 3 personality characteristics, with impulsivity decreasing over time. Compared with adolescents in the low risk group, adolescents in the dark impulsive and impulsive groups reported higher initial levels of substance use, sexual risk behaviors, permissive sexual attitudes, parent-adolescent conflict, and lower parent-adolescent satisfaction, as well as greater increases in sexual risk behavior over time. Compared with adolescents in the impulsive group, those in the dark impulsive group showed the highest levels of risk behaviors. Hence, dark personality traits coupled with impulsivity may be indicative of an earlier and more severe trajectory of problem behaviors that may differ from the trajectory of youth who are only impulsive. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  14. Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention

    OpenAIRE

    Andrew T. Ludlow; Stephen M. Roth

    2011-01-01

    Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence of the molecular and cellular factors associated with reduced disease risk and increased longevity resulting from physical activity is sparse. A long-standing hypothesis of aging is the telomere hypothesis: as a cell divides, telomeres shorten resulting eventually in replicative senescence and...

  15. The Nation and the Soldier in German Civil-Military Relations, 1800-1945

    National Research Council Canada - National Science Library

    Brumley, Donald W

    2005-01-01

    This study of civil-military relations addresses the parallel development of the professional soldier and the Prussian-German Army from 1806 until 1945, as well as the rise of nationalism in central...

  16. Expectations and experiences of gamete donors and donor-conceived adults searching for genetic relatives using DNA linking through a voluntary register.

    Science.gov (United States)

    van den Akker, O B A; Crawshaw, M A; Blyth, E D; Frith, L J

    2015-01-01

    experiences of donor-conceived adults and donors using a DNA-based voluntary register to seek information about and contact with genetic relatives and the first to measure aspects of identity using standardized measures. Findings provide valuable information about patterns of expectations and experiences of searching through DNA linking, identity and of having contact in the context of donor conception that will inform future research, practice and policy development. No funding was obtained for this study. The authors have no competing interests to declare except for M.C. who was national adviser to UKDL from 2003-2013. Not applicable. © The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. Going against the flow: A critical analysis of virtual water trade in the context of India's National River Linking Programme

    NARCIS (Netherlands)

    Verma, Shilp; Kampman, Doeke A.; van der Zaag, Pieter; Hoekstra, Arjen Ysbert

    2008-01-01

    Virtual water trade has been promoted as a tool to address national and regional water scarcity. In the context of international (food) trade, this concept has been applied with a view to optimize the flow of commodities considering the water endowments of nations. The concept states that water-rich

  18. The missing link: Mothers’ neural response to infant cry related to infant attachment behaviors

    Science.gov (United States)

    Laurent, Heidemarie K.; Ablow, Jennifer C.

    2012-01-01

    This study addresses a gap in the attachment literature by investigating maternal neural response to cry related to infant attachment classifications and behaviors. Twenty-two primiparous mothers and their 18-month old infants completed the Strange Situation Procedure (SS) to elicit attachment behaviors. During a separate functional MRI session, mothers were exposed to their own infant’s cry sound, as well as an unfamiliar infant’s cry and control sound. Maternal neural response to own infant cry related to both overall attachment security and specific infant behaviors. Mothers of less secure infants maintained greater activation to their cry in left parahippocampal and amygdala regions and the right posterior insula. consistent with a negative schematic response bias. Mothers of infants exhibiting more avoidant or contact maintaining behaviors during the SS showed diminished response across left prefrontal, parietal, and cerebellar areas involved in attentional processing and cognitive control. Mothers of infants exhibiting more disorganized behavior showed reduced response in bilateral temporal and subcallosal areas relevant to social cognition and emotion regulation. No differences by attachment classification were found. Implications for attachment transmission models are discussed. PMID:22982277

  19. The missing link: mothers' neural response to infant cry related to infant attachment behaviors.

    Science.gov (United States)

    Laurent, Heidemarie K; Ablow, Jennifer C

    2012-12-01

    This study addresses a gap in the attachment literature by investigating maternal neural response to cry related to infant attachment classifications and behaviors. Twenty-two primiparous mothers and their 18-month old infants completed the Strange Situation (SS) procedure to elicit attachment behaviors. During a separate functional MRI session, mothers were exposed to their own infant's cry sound, as well as an unfamiliar infant's cry and control sound. Maternal neural response to own infant cry related to both overall attachment security and specific infant behaviors. Mothers of less secure infants maintained greater activation to their cry in left parahippocampal and amygdala regions and the right posterior insula consistent with a negative schematic response bias. Mothers of infants exhibiting more avoidant or contact maintaining behaviors during the SS showed diminished response across left prefrontal, parietal, and cerebellar areas involved in attentional processing and cognitive control. Mothers of infants exhibiting more disorganized behavior showed reduced response in bilateral temporal and subcallosal areas relevant to social cognition and emotion regulation. No differences by attachment classification were found. Implications for attachment transmission models are discussed. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. The missing link between sleep disorders and age-related dementia: recent evidence and plausible mechanisms.

    Science.gov (United States)

    Zhang, Feng; Zhong, Rujia; Li, Song; Chang, Raymond Chuen-Chung; Le, Weidong

    2017-05-01

    Sleep disorders are among the most common clinical problems and possess a significant concern for the geriatric population. More importantly, while around 40% of elderly adults have sleep-related complaints, sleep disorders are more frequently associated with co-morbidities including age-related neurodegenerative diseases and mild cognitive impairment. Recently, increasing evidence has indicated that disturbed sleep may not only serve as the consequence of brain atrophy, but also contribute to the pathogenesis of dementia and, therefore, significantly increase dementia risk. Since the current therapeutic interventions lack efficacies to prevent, delay or reverse the pathological progress of dementia, a better understanding of underlying mechanisms by which sleep disorders interact with the pathogenesis of dementia will provide possible targets for the prevention and treatment of dementia. In this review, we briefly describe the physiological roles of sleep in learning/memory, and specifically update the recent research evidence demonstrating the association between sleep disorders and dementia. Plausible mechanisms are further discussed. Moreover, we also evaluate the possibility of sleep therapy as a potential intervention for dementia.

  1. On the link between column density distribution and density scaling relation in star formation regions

    Science.gov (United States)

    Veltchev, Todor; Donkov, Sava; Stanchev, Orlin

    2017-07-01

    We present a method to derive the density scaling relation ∝ L^{-α} in regions of star formation or in their turbulent vicinities from straightforward binning of the column-density distribution (N-pdf). The outcome of the method is studied for three types of N-pdf: power law (7/5≤α≤5/3), lognormal (0.7≲α≲1.4) and combination of lognormals. In the last case, the method of Stanchev et al. (2015) was also applied for comparison and a very weak (or close to zero) correlation was found. We conclude that the considered `binning approach' reflects rather the local morphology of the N-pdf with no reference to the physical conditions in a considered region. The rough consistency of the derived slopes with the widely adopted Larson's (1981) value α˜1.1 is suggested to support claims that the density-size relation in molecular clouds is indeed an artifact of the observed N-pdf.

  2. Construction of an integrated gene regulatory network link to stress-related immune system in cattle.

    Science.gov (United States)

    Behdani, Elham; Bakhtiarizadeh, Mohammad Reza

    2017-10-01

    The immune system is an important biological system that is negatively impacted by stress. This study constructed an integrated regulatory network to enhance our understanding of the regulatory gene network used in the stress-related immune system. Module inference was used to construct modules of co-expressed genes with bovine leukocyte RNA-Seq data. Transcription factors (TFs) were then assigned to these modules using Lemon-Tree algorithms. In addition, the TFs assigned to each module were confirmed using the promoter analysis and protein-protein interactions data. Therefore, our integrated method identified three TFs which include one TF that is previously known to be involved in immune response (MYBL2) and two TFs (E2F8 and FOXS1) that had not been recognized previously and were identified for the first time in this study as novel regulatory candidates in immune response. This study provides valuable insights on the regulatory programs of genes involved in the stress-related immune system.

  3. Operative Links

    DEFF Research Database (Denmark)

    Wistoft, Karen; Højlund, Holger

    2012-01-01

    and have been the object of great expectations concerning the ability to incorporate health concerns into every welfare area through health promotion strategies. The paper draws on results and analyses of a collective research project funded by the Danish National Research Council and carried out...... links' that indicate cooperative levels which facilitate a creative and innovative effort in disease prevention and health promotion targeted at children and adolescents - across traditional professional boundaries. It is proposed that such links are supported by network structures, shared semantics...

  4. National Survey of Oral/Dental Conditions Related to Tobacco and Alcohol Use in Mexican Adults

    Directory of Open Access Journals (Sweden)

    Carlo Eduardo Medina-Solís

    2014-03-01

    Full Text Available Oral diseases are a major burden on individuals and health systems. The aim of this study was to determine whether consumption of tobacco and alcohol were associated with the prevalence of oral/dental problems in Mexican adults. Using data from the National Performance Evaluation Survey 2003, a cross-sectional study part of the World Health Survey, dental information from a representative sample of Mexico (n = 22,229, N = 51,155,740 was used to document self-reported oral/dental problems in the 12 months prior to the survey. Questionnaires were used to collect information related to sociodemographic, socioeconomic, and other risk factors. Three models were generated for each age group (18–30, 31–45 and 46–98 years. The prevalence of oral/dental conditions was 25.7%. Adjusting for sex, schooling, socioeconomic position, diabetes, and self-reported health, those who used tobacco (sometimes or daily (OR = 1.15, p = 0.070; OR = 1.24, p < 0.01; and OR = 1.16, p < 0.05, for each age group respectively or alcohol (moderate or high (OR = 1.26, p < 0.001; OR = 1.18, p < 0.01 and OR = 1.30, p < 0.001, for each age group respectively had a higher risk of reporting oral/dental problems. Because tobacco and alcohol use were associated with self-reported oral/dental problems in one out of four adults, it appears advisable to ascertain how direct is such link; more direct effects would lend greater weight to adopting measures to reduce consumption of tobacco and alcohol for the specific purpose of improving oral health.

  5. Growing inter-Asian connections: Links, rivalries, and challenges in South Korean–Central Asian relations

    Directory of Open Access Journals (Sweden)

    Matteo Fumagalli

    2016-01-01

    Full Text Available The geopolitical context, which emerged from the collapse of the Soviet Union and the end of the Cold War, combined with Korea's growing economic prowess, enabled greater dynamism and diversification in Seoul's foreign policy-making. Growing pressure from energy-intensive economies coupled with new developments and investment in logistics and infrastructure has brought different parts of the Eurasian landmass closer together in recent years. Inter-Asian connections are especially growing. This article uses the case of deepening relations between Korea and the post-Soviet Central Asian republics as a vantage point to reflect on one such example of unfolding Asian inter-connectedness. In addition it sees Seoul's engagement in the region as a fitting example of Korea's broader ambitions to assert itself as a global economic player. The article shows that Korea's policy toward Central Asia has been primarily driven by energy needs and is defined by pragmatism. It finds that the economic dimension of the relationship has greatly overshadowed other aspects such as politics and security. In its pursuit of closer ties with the region Seoul has sought to turn structural weaknesses into added value and has attempted to develop a distinctive, non-threatening profile built around the lack of a political baggage and geopolitical ambitions, and the desire to share its experience of formerly impoverished turned leading economy. In turn, Central Asia's selective integration in the world economy has continued, also thanks to its ties with Korea. The Central Asian republics welcomed the opportunity to diversify their foreign relations, the sources of foreign investment and export routes. At the same time the opaque business environment, a leadership succession, which cannot be postponed for much longer, and Seoul's “no-strings attached” approach expose Korea to some risks as regime stability might not last forever.

  6. The links between healthy, problematic, and addicted Internet use regarding comorbidities and self-concept-related characteristics.

    Science.gov (United States)

    Leménager, Tagrid; Hoffmann, Sabine; Dieter, Julia; Reinhard, Iris; Mann, Karl; Kiefer, Falk

    2018-03-01

    Background Addicted Internet users present with higher rates of comorbidities, e.g., attention-deficit hyperactivity disorder (ADHD), depressive, and anxiety disorders. In addition, deficits in self-concept-related characteristics were found in addicted Internet gamers and social network users. The aim of this study was to examine the links between healthy, problematic, and addicted Internet use regarding comorbidities and self-concept-related characteristics. The association between recently developed ADHD-like symptoms without an underlying diagnosis and addictive Internet use was also examined. Methods n = 79 healthy controls, n = 35 problematic, and n = 93 addicted Internet users were assessed for comorbidities, social and emotional competencies, body image, self-esteem, and perceived stress. Apart from an ADHD-diagnosis, recently developed ADHD-like symptoms were also assessed. Results Addicted users showed more self-concept-related deficits and higher rates of comorbidities with ADHD, depressive, and anxiety disorders. Addicted and problematic users showed similarities in the prevalence of cluster B personality disorders and decreased levels of characteristics related to emotional intelligence. Participants with recently developed ADHD-like symptoms scored higher in lifetime and current severity of Internet use compared with those without ADHD symptoms. Addicted participants with recently developed ADHD symptoms showed higher lifetime Internet use severity compared with those without any symptoms. Conclusions Our findings indicate that cluster B personality disorders and premorbid problems in emotional intelligence might present a link between problematic and addictive Internet use. Furthermore, the findings provide a first indication that addictive Internet use is related to ADHD-like symptoms. Symptoms of ADHD should therefore be assessed against the background of possible addicted Internet use.

  7. Linking Excessive Heat with Daily Heat-Related Mortality over the Coterminous United States

    Science.gov (United States)

    Quattrochi, Dale A.; Crosson, William L.; Al-Hamdan, Mohammad Z.; Estes, Maurice G., Jr.

    2014-01-01

    In the United States, extreme heat is the most deadly weather-related hazard. In the face of a warming climate and urbanization, which contributes to local-scale urban heat islands, it is very likely that extreme heat events (EHEs) will become more common and more severe in the U.S. This research seeks to provide historical and future measures of climate-driven extreme heat events to enable assessments of the impacts of heat on public health over the coterminous U.S. We use atmospheric temperature and humidity information from meteorological reanalysis and from Global Climate Models (GCMs) to provide data on past and future heat events. The focus of research is on providing assessments of the magnitude, frequency and geographic distribution of extreme heat in the U.S. to facilitate public health studies. In our approach, long-term climate change is captured with GCM outputs, and the temporal and spatial characteristics of short-term extremes are represented by the reanalysis data. Two future time horizons for 2040 and 2090 are compared to the recent past period of 1981- 2000. We characterize regional-scale temperature and humidity conditions using GCM outputs for two climate change scenarios (A2 and A1B) defined in the Special Report on Emissions Scenarios (SRES). For each future period, 20 years of multi-model GCM outputs are analyzed to develop a 'heat stress climatology' based on statistics of extreme heat indicators. Differences between the two future and the past period are used to define temperature and humidity changes on a monthly time scale and regional spatial scale. These changes are combined with the historical meteorological data, which is hourly and at a spatial scale (12 km) much finer than that of GCMs, to create future climate realizations. From these realizations, we compute the daily heat stress measures and related spatially-specific climatological fields, such as the mean annual number of days above certain thresholds of maximum and minimum air

  8. Sandia`s network for Supercomputing `94: Linking the Los Alamos, Lawrence Livermore, and Sandia National Laboratories using switched multimegabit data service

    Energy Technology Data Exchange (ETDEWEB)

    Vahle, M.O.; Gossage, S.A.; Brenkosh, J.P. [Sandia National Labs., Albuquerque, NM (United States). Advanced Networking Integration Dept.

    1995-01-01

    Supercomputing `94, a high-performance computing and communications conference, was held November 14th through 18th, 1994 in Washington DC. For the past four years, Sandia National Laboratories has used this conference to showcase and focus its communications and networking endeavors. At the 1994 conference, Sandia built a Switched Multimegabit Data Service (SMDS) network running at 44.736 megabits per second linking its private SMDS network between its facilities in Albuquerque, New Mexico and Livermore, California to the convention center in Washington, D.C. For the show, the network was also extended from Sandia, New Mexico to Los Alamos National Laboratory and from Sandia, California to Lawrence Livermore National Laboratory. This paper documents and describes this network and how it was used at the conference.

  9. Neighborhood linking social capital as a predictor of psychiatric medication prescription in the elderly: a Swedish national cohort study.

    Science.gov (United States)

    Sundquist, Jan; Hamano, Tsuyoshi; Li, Xinjun; Kawakami, Naomi; Shiwaku, Kuninori; Sundquist, Kristina

    2014-08-01

    Little is known about the association between neighborhood linking social capital and psychiatric medication in the elderly. The present study analyzes whether there is an association between linking social capital (a theoretical concept describing the amount of trust between individuals and societal institutions) and prescription of antipsychotics, anxiolytics, hypnotics/sedatives, antidepressants, or anti-dementia drugs. The entire Swedish population aged 65+, a total of 1,292,816 individuals, were followed from 1 July 2005 until first prescription of psychiatric medication, death, emigration, or the end of the study on 31 December 2010. Small geographic units were used to define neighborhoods. The definition of linking social capital was based on mean voting participation in each neighborhood unit, categorized in three groups. Multilevel logistic regression was used to estimate odds ratios (ORs) and between-neighborhood variance in three different models. There was an inverse association between the level of linking social capital and prescription of psychiatric medications (except for anti-dementia drugs). The associations decreased, but remained significant, after accounting for age, sex, family income, marital status, country of birth, and education level (except for antidepressants). The OR for prescription of antipsychotics in the crude model was 1.65 (95% CI 1.53-1.78) and decreased, but remained significant (OR = 1.26; 95% CI 1.17-1.35), after adjustment for the individual-level sociodemographic variables. Decision-makers should take into account the potentially negative effect of linking social capital on psychiatric disorders when planning sites of primary care centers and psychiatric clinics, as well as other kinds of community support for elderly patients with such disorders. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Link between Motor Competence and Health Related Fitness in Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Carlos Luz

    2017-06-01

    Full Text Available This study examined motor competence (MC behavior in 6- to 14-year-old children, and investigated the differences in health-related fitness (HRF between high and low MC groups, according to sex and age. A sample of 564 children (288 males participated in this study, divided into three age groups (6–8 years; 9–11 years; 12–14 years. Total MC and its three components (stability, locomotor, and manipulative were assessed with a quantitative instrument. HRF was evaluated using a maximal multistage 20-m shuttle-run test and the handgrip test. Participants were divided into tertiles according to their MC level and high and low MC groups were analyzed. Overall, MC increased across age groups for both sexes, but boys presented better results than girls. The high MC group outperformed their low MC peers in all HRF variables, independent of their age group. Although cardiovascular fitness increased with age for both the high and low MC groups, the differences between these groups were greater in older children compared to younger children, within the study age range. The findings suggest that MC interventions should be considered as an important strategy to enhance HRF, and girls at a young age should be a priority target.

  11. Link between Motor Competence and Health Related Fitness in Children and Adolescents.

    Science.gov (United States)

    Luz, Carlos; Cordovil, Rita; Almeida, Gabriela; Rodrigues, Luis P

    2017-06-15

    This study examined motor competence (MC) behavior in 6- to 14-year-old children, and investigated the differences in health-related fitness (HRF) between high and low MC groups, according to sex and age. A sample of 564 children (288 males) participated in this study, divided into three age groups (6⁻8 years; 9⁻11 years; 12⁻14 years). Total MC and its three components (stability, locomotor, and manipulative) were assessed with a quantitative instrument. HRF was evaluated using a maximal multistage 20-m shuttle-run test and the handgrip test. Participants were divided into tertiles according to their MC level and high and low MC groups were analyzed. Overall, MC increased across age groups for both sexes, but boys presented better results than girls. The high MC group outperformed their low MC peers in all HRF variables, independent of their age group. Although cardiovascular fitness increased with age for both the high and low MC groups, the differences between these groups were greater in older children compared to younger children, within the study age range. The findings suggest that MC interventions should be considered as an important strategy to enhance HRF, and girls at a young age should be a priority target.

  12. Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders

    Directory of Open Access Journals (Sweden)

    Freddy Jeanneteau

    2016-01-01

    Full Text Available The brain evolved cellular mechanisms for adapting synaptic function to energy supply. This is particularly evident when homeostasis is challenged by stress. Signaling loops between the mitochondria and synapses scale neuronal connectivity with bioenergetics capacity. A biphasic “inverted U shape” response to the stress hormone glucocorticoids is demonstrated in mitochondria and at synapses, modulating neural plasticity and physiological responses. Low dose enhances neurotransmission, synaptic growth, mitochondrial functions, learning, and memory whereas chronic, higher doses produce inhibition of these functions. The range of physiological effects by stress and glucocorticoid depends on the dose, duration, and context at exposure. These criteria are met by neuronal activity and the circadian, stress-sensitive and ultradian, stress-insensitive modes of glucocorticoid secretion. A major hallmark of stress-related neuropsychiatric disorders is the disrupted glucocorticoid rhythms and tissue resistance to signaling with the glucocorticoid receptor (GR. GR resistance could result from the loss of context-dependent glucocorticoid signaling mediated by the downregulation of the activity-dependent neurotrophin BDNF. The coincidence of BDNF and GR signaling changes glucocorticoid signaling output with consequences on mitochondrial respiration efficiency, synaptic plasticity, and adaptive trajectories.

  13. LINKING MOTOR-RELATED BRAIN POTENTIALS AND VELOCITY PROFILES IN MULTI-JOINT ARM REACHING MOVEMENTS

    Directory of Open Access Journals (Sweden)

    Julià L Amengual

    2014-04-01

    Full Text Available The study of the movement related brain potentials (MRPBs needs accurate technical approaches to disentangle the specific patterns of bran activity during the preparation and execution of movements. During the last forty years, synchronizing the electromiographic activation (EMG of the muscle with the electrophysiological recordings (EEG has been commonly ussed for these purposes. However, new clinical approaches in the study of motor diseases and rehabilitation suggest the demand of new paradigms that might go further into the study of the brain activity associated with the kinematics of movement. As a response to this call, we have used a 3-D hand tracking system with the aim to record continuously the position of an ultrasonic sender located on the hand during the performance of multi-joint self-pace movements. We synchronized the time-series of position of velocity of the sender with the EEG recordings, obtaining specific patterns of brain activity as a function of the fluctuations of the kinematics during the natural movement performance. Additionally, the distribution of the brain activity during the preparation and execution phases of movement was similar that reported previously using the EMG, suggesting the validity of our technique. We claim that this paradigm could be usable in patients because of its simplicity and the potential knowledge that can be extracted from clinical protocols.

  14. Geriatric Patient Safety Indicators Based on Linked Administrative Health Data to Assess Anticoagulant-Related Thromboembolic and Hemorrhagic Adverse Events in Older Inpatients: A Study Proposal.

    Science.gov (United States)

    Le Pogam, Marie-Annick; Quantin, Catherine; Reich, Oliver; Tuppin, Philippe; Fagot-Campagna, Anne; Paccaud, Fred; Peytremann-Bridevaux, Isabelle; Burnand, Bernard

    2017-05-11

    -based algorithms, (3) empirical measurement of indicators using linked administrative health data, (4) validation of indicators, (5) analyses of geographic and temporal variations for reliable and valid indicators, and (6) data visualization. Study populations will consist of 166,670 Swiss and 5,902,037 French residents aged 65 years and older admitted to an acute care hospital at least once during the 2012-2014 period and insured for at least 1 year before admission and 1 year after discharge. We will extract Swiss data from the Helsana Group data warehouse and French data from the national health insurance information system (SNIIR-AM). The study has been approved by Swiss and French ethics committees and regulatory organizations for data protection. Validated GPSIs and GQIs should help support and drive quality and safety improvement in older inpatients, inform health care stakeholders, and enable international comparisons. We discuss several limitations relating to the representativeness of study populations, accuracy of administrative health data, methods used for GPSI criterion validity assessment, and potential confounding bias in comparisons based on GQIs, and we address these limitations to strengthen study feasibility and validity. ©Marie-Annick Le Pogam, Catherine Quantin, Oliver Reich, Philippe Tuppin, Anne Fagot-Campagna, Fred Paccaud, Isabelle Peytremann-Bridevaux, Bernard Burnand. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 11.05.2017.

  15. Regorafenib-induced hypothyroidism and cancer-related fatigue: is there a potential link?

    Science.gov (United States)

    Pani, Fabiana; Massidda, Matteo; Pusceddu, Valeria; Puzzoni, Marco; Massa, Elena; Madeddu, Clelia; Scartozzi, Mario; Mariotti, Stefano

    2017-07-01

    Thyroid dysfunction has been reported during Regorafenib (Reg) administration, but no detailed study is presently available. Prospective, observational cohort study. Patients with documented metastatic colorectal cancer and progression of disease during or within 3 months after the last standard therapy, with no evidence and history of previous thyroid disease were enrolled. Twenty-five consecutive patients were evaluated before and 8-50 weeks after initiating Reg therapy by monthly clinical, ultrasound and laboratory (thyrotropin (TSH), free thyroxine (fT4), antithyroglobulin (TgAb) and antithyroid peroxidase (TPOAb)) evaluation. Thirteen/25 patients (52%) became hypothyroid (TSH: 12.5 ± 4.01 IU/L, range: 4.6-22.0) within 5 months of therapy. TPOAb became detectable (99-155 IU/mL) in 2/25 (8%) patients. Thyroid volume progressively decreased (from 8.6  ±  2.2 mL to 4.9 ± 2.4 mL after 5 months of Reg therapy, P  hypothyroidism (43 weeks) than in those remaining euthyroid (17 weeks, P  hypothyroidism severity and reversed after levothyroxine therapy (L-T4). Reg rapidly causes hypothyroidism in about 50% of patients and in a minority of them also triggers thyroid autoimmunity. Reg-induced hypothyroidism was strictly related to fatigue, easily reversed by L-T4 administration and associated to longer survival. These results suggest that prompt recognition of hypothyroidism in patients with severe fatigue may prevent unnecessary Reg dose reduction or withdrawal. © 2017 European Society of Endocrinology.

  16. Osteomalacia: the missing link in the pathogenesis of bisphosphonate-related osteonecrosis of the jaws?

    Science.gov (United States)

    Bedogni, Alberto; Saia, Giorgia; Bettini, Giordana; Tronchet, Anita; Totola, Andrea; Bedogni, Giorgio; Tregnago, Paolo; Valenti, Maria Teresa; Bertoldo, Francesco; Ferronato, Giuseppe; Nocini, Pier Francesco; Blandamura, Stella; Dalle Carbonare, Luca

    2012-01-01

    Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a well-documented adverse event from treatment with nitrogen-containing bisphosphonates (NBPs). During a preliminary histomorphometric study aimed at assessing the rate of bone remodeling in the jaws of patients with surgically resected BRONJ, we found a defect of bone mineralization (unpublished data). We hypothesized that osteomalacia could be a risk factor for BRONJ in patients taking NBPs. Therefore, we looked for static and dynamic histomorphometric evidence of osteomalacia in biopsies from subjects with and without BRONJ. This case-control study used histomorphometric analysis of bone specimens of patients using NBPs (22 patients with BRONJ and 21 patients without BRONJ) who required oral surgical interventions for the treatment/prevention of osteonecrosis. Patients were given tetracycline hydrochloride according to a standardized protocol before taking bone biopsies from their jaws. Biopsies with evidence of osteomyelitis or necrosis at histology were excluded from the study. Osteomalacia was defined as a mineralization lag time >100 days, a corrected mean osteoid thickness >12.5 mm, and an osteoid volume >10%. In all, 77% of patients with BRONJ were osteomalacic compared with 5% of patients without BRONJ, according to histomorphometry. Because osteomalacia was found almost exclusively in NBP users with BRONJ, this is likely to be a generalized process in which the use of NBPs further deteriorates mechanisms of bone repair. Osteomalacia represents a new and previously unreported risk factor for disease development. This finding may contribute to a better understanding of the pathogenesis of this disease and help with the development of strategies to increase the safety of NBP administration.

  17. Olympic citizenship and the (un)specialness of the national vest: rethinking the links between sport and citizenship law

    NARCIS (Netherlands)

    Kostakopoulou, D.; Schrauwen, A.

    2014-01-01

    The increasing mobility of athletes prompts a reconsideration of the presumed connection between allegiance, identity and nationality. Olympic citizenship challenges traditional understandings of community membership by calling into question the privileged status of birthright citizenship and by

  18. Absorbing aerosols at high relative humidity: linking hygroscopic growth to optical properties

    Directory of Open Access Journals (Sweden)

    J. Michel Flores

    2012-06-01

    Full Text Available One of the major uncertainties in the understanding of Earth's climate system is the interaction between solar radiation and aerosols in the atmosphere. Aerosols exposed to high humidity will change their chemical, physical, and optical properties due to their increased water content. To model hydrated aerosols, atmospheric chemistry and climate models often use the volume weighted mixing rule to predict the complex refractive index (RI of aerosols when they interact with high relative humidity, and, in general, assume homogeneous mixing. This study explores the validity of these assumptions. A humidified cavity ring down aerosol spectrometer (CRD-AS and a tandem hygroscopic DMA (differential mobility analyzer are used to measure the extinction coefficient and hygroscopic growth factors of humidified aerosols, respectively. The measurements are performed at 80% and 90%RH at wavelengths of 532 nm and 355 nm using size-selected aerosols with different degrees of absorption; from purely scattering to highly absorbing particles. The ratio of the humidified to the dry extinction coefficients (fRHext(%RH, Dry is measured and compared to theoretical calculations based on Mie theory. Using the measured hygroscopic growth factors and assuming homogeneous mixing, the expected RIs using the volume weighted mixing rule are compared to the RIs derived from the extinction measurements.

    We found a weak linear dependence or no dependence of fRH(%RH, Dry with size for hydrated absorbing aerosols in contrast to the non-monotonically decreasing behavior with size for purely scattering aerosols. No discernible difference could be made between the two wavelengths used. Less than 7% differences were found between the real parts of the complex refractive indices derived and those calculated using the volume weighted mixing rule, and the imaginary parts had up to a 20% difference. However, for substances with growth factor less than 1

  19. 77 FR 19525 - National School Lunch Program: School Food Service Account Revenue Amendments Related to the...

    Science.gov (United States)

    2012-04-02

    ... National School Lunch Program: School Food Service Account Revenue Amendments Related to the Healthy... Food Service Account Revenue Amendments Related to the Healthy, Hunger-Free Kids Act of 2010'' on June... sold in a school and purchased with funds from the nonprofit school food service account, other than...

  20. 78 FR 16715 - National Council on Federal Labor-Management Relations Meeting

    Science.gov (United States)

    2013-03-18

    ... functions listed in Section 1(b) of the Executive Order. The meetings are open to the public. Please contact... OFFICE OF PERSONNEL MANAGEMENT National Council on Federal Labor-Management Relations Meeting... Federal Labor-Management Relations plans to meet on the following date-- Wednesday, May 15, 2013. The...

  1. Business continuity and disaster management within the public service in relation to a national development plan.

    Science.gov (United States)

    Ferguson, Cliff

    2018-01-01

    Within South Africa, few public service departments understand the concepts of business continuity management (BCM) and what it takes to implement a well-constructed business continuity plan. Likewise, few of these entities understand the purpose of designing and maintaining resilient systems that are immune to incidents. This paper discusses the integration of the South African Disaster Management Act 2002, the Disaster Management Framework and the National Development Plan, linking these to BCM, through a resilience period model, as a means for the implementation of resilience strategies. The goals of the National Development Plan are outlined with a view to how resilience can be achieved in each. A resilience period model has been advocated for the implementation of projects within the public sector in order to provide continuity and sustainability.

  2. Reducing Risks to Women Linked to Shift Work, Long Work Hours, and Related Workplace Sleep and Fatigue Issues.

    Science.gov (United States)

    Caruso, Claire C

    2015-10-01

    In the United States, an estimated 12% to 28% of working women are on shift work schedules, and 12% work more than 48 hours per week. Shift work and long work hours are associated with many health and safety risks, including obesity, injuries, and negative reproductive outcomes. Over time, the worker is at risk for developing a wide range of chronic diseases. These work schedules can also strain personal relationships, owing to fatigue and poor mood from sleep deprivation and reduced quality time to spend with family and friends. Worker errors from fatigue can lead to reduced quality of goods and services, negatively impacting the employer. In addition, mistakes by fatigued workers can have far-reaching negative effects on the community, ranging from medical care errors to motor vehicle crashes and industrial disasters that endanger others. To reduce the many risks that are linked to these demanding work hours, the National Institute for Occupational Safety and Health (NIOSH) conducts research, develops guidance and authoritative recommendations, and translates and disseminates scientific information to protect workers, their families, employers, and the community. The key message to reduce these risks is making sleep a priority in the employer's systems for organizing work and in the worker's personal life. The NIOSH website has freely available online training programs with suggestions for workers and their managers to help them better cope with this workplace hazard.

  3. The study of Relation between Cultural Components and National Attachment among Citizens of Yazd city.

    Directory of Open Access Journals (Sweden)

    M. Farahmand

    2017-03-01

    Full Text Available National attachment sense as one of the components of social Property is a key word in national culture. Any definition of society is Occurred by accepting attachment and commitment sense and the society is existed to some extent because people have positive sense about that. National attachment sense is considered as one the important affairs of any society and its proper recognition and full knowledge of authorities and affair operators about the effective social factors on that can be an effective step in recognizing the existent problems in society. The present research reviewed the relation between cultural components and national attachment among the Yazd citizens. The research statistical society was all of the Yazd’s 15 to 65 years old citizens that 384 people were selected as sample by Cochran formula. The tool of data gathering was researcher-made questionnaire that had appropriate validity and reliability. Sampling method has been multi-stage clustered. Results showed that there was a meaningful relationship between secularization, consumerism and virtual social networks with national attachment has been reverse and meaningful, but the relationship between age and values preferences with national attachment has been direct and meaningful. Independent variables in regression equation managed to explain 39 percent of national attachment variable changes. The greatest impact on dependent variable (national attachment has belonged to the variables of secularization, age, values preferences and consumerism.

  4. Association between home visiting interventions and First Nations families' health and social outcomes in Manitoba, Canada: protocol for a study of linked population-based administrative data.

    Science.gov (United States)

    Brownell, Marni D; Nickel, Nathan C; Enns, Jennifer E; Chartier, Mariette; Campbell, Rhonda; Phillips-Beck, Wanda; Chateau, Dan; Burland, Elaine; Santos, Rob; Katz, Alan

    2017-10-10

    First Nations people are descendants of Canada's original inhabitants. In consequence of historical and ongoing structural injustices, many First Nations families struggle with challenging living conditions, including high rates of poverty, poor housing conditions, mental illness and social isolation. These risk factors impede caregivers' abilities to meet their children's basic physical and psychosocial needs. Home visiting programmes were developed to support child developmental health in families facing parenting challenges. However, whether home visiting is an effective intervention for First Nations families has not been examined. We are evaluating two home visiting programmes in Manitoba, Canada, to determine whether they promote nurturing family environments for First Nations children. This research builds on new and established relationships among academic researchers, government decision-makers and First Nations stakeholders. We will link health, education and social services data from the Manitoba Population Research Data Repository to data from two home visiting programmes in Manitoba. Logistic regression modelling will be used to assess whether programme participation is associated with improved child developmental health, better connections between families and social services, reduced instances of child maltreatment and being taken into out-of-home care by child welfare and reduced inequities for First Nations families. Non-participating individuals with similar sociodemographic characteristics will serve as comparators. We will use an interrupted time series approach to test for differences in outcomes before and after programme implementation and a propensity score analysis to compare differences between participants and non-participants. Approvals were granted by the Health Information Research Governance Committee of the First Nations Health and Social Secretariat of Manitoba and the University of Manitoba Health Research Ethics Board. Our

  5. Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7

    Energy Technology Data Exchange (ETDEWEB)

    Duggirala, R.; Stern, M.P.; Reinhart, L.J. [Univ. of Texas Health Science Center, San Antonio, TX (United States)] [and others

    1996-09-01

    Despite the evidence that human obesity has strong genetic determinants, efforts at identifying specific genes that influence human obesity have largely been unsuccessful. Using the sibship data obtained from 32 low-income Mexican American pedigrees ascertained on a type II diabetic proband and a multipoint variance-components method, we tested for linkage between various obesity-related traits plus associated metabolic traits and 15 markers on human chromosome 7. We found evidence for linkage between markers in the OB gene region and various traits, as follows: D7S514 and extremity skinfolds (LOD = 3.1), human carboxypeptidase A1 (HCPA1) and 32,33-split proinsulin level (LOD = 4.2), and HCPA1 and proinsulin level (LOD = 3.2). A putative susceptibility locus linked to the marker D7S514 explained 56% of the total phenotypic variation in extremity skinfolds. Variation at the HCPA1 locus explained 64% of phenotypic variation in proinsulin level and {approximately}73% of phenotypic variation in split proinsulin concentration, respectively. Weaker evidence for linkage to several other obesity-related traits (e.g., waist circumference, body-mass index, fat mass by bioimpedance, etc.) was observed for a genetic location, which is {approximately}15 cM telomeric to OB. In conclusion, our study reveals that the OB region plays a significant role in determining the phenotypic variation of both insulin precursors and obesity-related traits, at least in Mexican Americans. 66 refs., 3 figs., 4 tabs.

  6. The Relative Age Effect On The Selection In The Slovakia National Football Teams

    Directory of Open Access Journals (Sweden)

    Mikulič Martin

    2015-11-01

    Full Text Available The focus of this research was to determine the relative age effect (RAE on selection in the Slovakia national football teams. A factor that may have a significant impact on the quality of players chosen for the national teams or may result in a poor selection of players for the elite teams. Anthropometric and cognitive acceleration of players born in the first months of the calendar year concerning the overall context of the competition for placement in the national teams may be considered as a significant advantage. The aim of this research was to examine, determine and verify the presence of relative age effect in the selection of football players for the Slovakia national teams starting with the under 16 age category (U-16 through to the A - senior national football team. We presumed that the elite teams under this review and study consisted predominantly of players born in the first quarter of the calendar year, while also presuming that relative age effect receded with the increasing age category. Our survey sample U16 consisted of 79 players, U17 consisted of 47 players, U18 consisted of 58 players, U19 consisted of 71 players, U21 consisted of 52 players and A - senior national team consisted of 302 Slovakia national football players. The information obtained from the Slovak Football Association has been processed by the application of statistical methods and statistical significance test (T-test. Our research confirmed the presence of relative age effect in the U-16, U-17 and U-18 teams under our investigation (p≤0.01. In the U19 and U21 age categories, statistical significance has not been confirmed. As for the senior national team, statistically significant difference has been found in relation to players born in the last quarter of the year as opposed to players born in the first three months of the year (p≤0.01. Our results have shown that with the increasing age, the relative age effect fades and vanishes in full in the

  7. Expanding the g-Nexus: Further Evidence Regarding the Relations among National IQ, Religiosity and National Health Outcomes

    Science.gov (United States)

    Reeve, Charlie L.

    2009-01-01

    The current study seeks to better understand how religiosity and health are positioned within the g-nexus. Specifically, the degree to which differences in average IQ across nations is associated with differences in national religiosity (i.e., belief rate) and national health statistics independent of differences in national wealth is examined.…

  8. Are the metabolomic responses to folivory of closely related plant species linked to macroevolutionary and plant-folivore coevolutionary processes?

    Energy Technology Data Exchange (ETDEWEB)

    Rivas-Ubach, Albert [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland Washington 99354 USA; CREAF, Cerdanyola del Vallès 08913 Catalonia Spain; Hódar, José A. [Grupo de Ecología Terrestre, Departamento de Biología Animal y Ecología, Facultad de Ciencias, Universidad de Granada, 18071 Granada Spain; Sardans, Jordi [CREAF, Cerdanyola del Vallès 08913 Catalonia Spain; CSIC, Global Ecology Unit CREAF-CEAB-CSIC-UAB, Cerdanyola del Vallès 08913 Catalonia Spain; Kyle, Jennifer E. [Biological Sciences Division, Pacific Northwest National Laboratory, Richland Washington 99354 USA; Kim, Young-Mo [Biological Sciences Division, Pacific Northwest National Laboratory, Richland Washington 99354 USA; Oravec, Michal [Global Change Research Centre, Academy of Sciences of the Czech Republic, Bĕlidla 4a CZ-603 00 Brno Czech Republic; Urban, Otmar [Global Change Research Centre, Academy of Sciences of the Czech Republic, Bĕlidla 4a CZ-603 00 Brno Czech Republic; Guenther, Alex [Department of Earth System Science, University of California, Irvine California 92697 USA; Peñuelas, Josep [CREAF, Cerdanyola del Vallès 08913 Catalonia Spain; CSIC, Global Ecology Unit CREAF-CEAB-CSIC-UAB, Cerdanyola del Vallès 08913 Catalonia Spain

    2016-06-02

    The debate whether the coevolution of plants and insects or macroevolutionary processes (phylogeny) is the main driver determining the arsenal of molecular defensive compounds of plants remains unresolved. Attacks by herbivorous insects affect not only the composition of defensive compounds in plants but the entire metabolome (the set of molecular metabolites), including defensive compounds. Metabolomes are the final products of genotypes and are directly affected by macroevolutionary processes, so closely related species should have similar metabolomic compositions and may respond in similar ways to attacks by folivores. We analyzed the elemental compositions and metabolomes of needles from Pinus pinaster, P. nigra and P. sylvestris to determine if these closely related Pinus species with different coevolutionary histories with the caterpillars of the processionary moth respond similarly to attacks by this lepidopteran. All pines had different metabolomes and metabolic responses to herbivorous attack. The metabolomic variation among the pine species and the responses to folivory reflected their macroevolutionary relationships, with P. pinaster having the most divergent metabolome. The concentrations of phenolic metabolites were generally not higher in the attacked trees, which had lower concentrations of terpenes, suggesting that herbivores avoid individuals with high concentrations of terpenes. Our results suggest that macroevolutionary history plays important roles in the metabolomic responses of these pine species to folivory, but plant-insect coevolution probably constrains those responses. Combinations of different evolutionary factors and trade-offs are likely responsible for the different responses of each species to folivory, which is not necessarily exclusively linked to plant-insect coevolution.

  9. National Estimates of Marijuana Use and Related Indicators - National Survey on Drug Use and Health, United States, 2002-2014.

    Science.gov (United States)

    Azofeifa, Alejandro; Mattson, Margaret E; Schauer, Gillian; McAfee, Tim; Grant, Althea; Lyerla, Rob

    2016-09-02

    In the United States, marijuana is the most commonly used illicit drug. In 2013, 7.5% (19.8 million) of the U.S. population aged ≥12 years reported using marijuana during the preceding month. Because of certain state-level policies that have legalized marijuana for medical or recreational use, population-based data on marijuana use and other related indicators are needed to help monitor behavioral health changes in the United States. 2002-2014. The National Survey on Drug Use and Health (NSDUH) is a national- and state-level survey of a representative sample of the civilian, noninstitutionalized U.S. population aged ≥12 years. NSDUH collects information about the use of illicit drugs, alcohol, and tobacco; initiation of substance use; frequency of substance use; substance dependence and abuse; perception of substance harm risk or no risk; and other related behavioral health indicators. This report describes national trends for selected marijuana use and related indicators, including prevalence of marijuana use; initiation; perception of harm risk, approval, and attitudes; perception of availability and mode of acquisition; dependence and abuse; and perception of legal penalty for marijuana possession. In 2014, a total of 2.5 million persons aged ≥12 years had used marijuana for the first time during the preceding 12 months, an average of approximately 7,000 new users each day. During 2002-2014, the prevalence of marijuana use during the past month, past year, and daily or almost daily increased among persons aged ≥18 years, but not among those aged 12-17 years. Among persons aged ≥12 years, the prevalence of perceived great risk from smoking marijuana once or twice a week and once a month decreased and the prevalence of perceived no risk increased. The prevalence of past year marijuana dependence and abuse decreased, except among persons aged ≥26 years. Among persons aged ≥12 years, the percentage reporting that marijuana was fairly easy or very easy

  10. The link between industry and social interests in health in Brazil's National Health Innovation System: the experience of the Brazilian National Institute of Traumatology and Orthopedics (INTO).

    Science.gov (United States)

    Vianna, Cid Manso de Mello; Fermam, Marcelo Kropf Santos; Rodrigues, Marcus Paulo da Silva; Mosegui, Gabriela Bittencourt Gonzalez

    2016-11-03

    This article has two parts. The first discusses the relationship between industry and health interests based on three different but non-mutually exclusive "logics": (a) independent; (b) divergent; and (c) convergent. The second part describes the experience at the Brazilian National Institute of Traumatology and Orthopedics (INTO) with a technology management model. The accumulated expertise in orthopedics at INTO can favor Brazil's domestic medical equipment industry without jeopardizing the country's social health needs. This means directing the production of feasible technologies adapted to the national reality, with a focus on safety and quality, without burdening the public coffers and by overcoming the country's dependency on imported products. The proposal is to promote socioeconomic development through a virtuous circle by attracting reserves and fomenting national competitiveness in domestic and foreign markets while improving social conditions and access to health. Resumo: Este artigo está dividido em duas partes. Na primeira, discute-se como se relacionam os interesses produtivos e a saúde a partir de três "lógicas" ou perspectivas diferentes que não são mutuamente excludentes: (a) independente; (b) divergente e (c) convergente. Na segunda, descreve-se a experiência do Instituto Nacional de Traumatologia e Ortopedia (INTO) na montagem de um modelo de gestão de tecnologia. O conhecimento internalizado em ortopedia do INTO pode favorecer a indústria nacional de equipamentos médicos sem abandonar as necessidades sociais brasileiras de saúde. Isto é, direcionar a produção de tecnologias viáveis e adaptadas à realidade nacional, com foco em segurança e qualidade, sem onerar os cofres públicos e abandonando a dependência de produtos importados. A proposta é a de promover um desenvolvimento socioeconômico que construa um ciclo virtuoso, por atrair divisas e fomentar a competitividade nacional em mercados internos e externos, melhorando as

  11. Decreased expression of the ATM gene linked to poor prognosis for gastric cancer of different nationalities in Xinjiang.

    Science.gov (United States)

    Han, Mei; Ma, Lanying; Qu, Yanli; Tang, Yong

    2017-08-01

    To explore the clinicopathological significance of ATM gene in the occurrence and prognosis of gastric cancer (GC) from different nationalities in Xinjiang. The expression of ATM in 385 patients with GC (including 98 Uygurs, 231 Hans and 56 Kazaks) and its corresponding adjacent tissues were examined by quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry assay to, analyze its correlations with clinicopathological features and prognosis of GC. The ATM expression in GC tissues was significantly decreased when compared to that in adjacent normal tissues of Uygur, Han and Kazak patients in Xinjiang, while Uygurs and Kazaks were much lower than Hans in the ATM expression of GC tissues (all PATM-negative tumors had a markedly lower survival rate than patients in Hans (P=0.028), and GC patients with ATM negative expression presented more unfavorable overall survival rate than those with positive expression among the three different nationalities (all PATM expression, TNM staging, depth of invasion, and lymph node metastasis were independent factors affecting the prognosis of GC patients in Xinjiang (all PATM was downregulated in GC patients in Xinjiang, especially for Uygurs and Kazaks, which suggested ATM to be an independent indicator of prognosis for GC therapy. Copyright © 2017 Elsevier GmbH. All rights reserved.

  12. Investigating the link between liking versus wanting self-esteem and depression in a nationally representative sample of American adults.

    Science.gov (United States)

    Bushman, Brad J; Moeller, Scott J; Konrath, Sara; Crocker, Jennifer

    2012-10-01

    The self-esteem movement has been around since the 1970s, and may have influenced how much value people place on self-esteem. We predicted a negative relationship between age and the amount of value placed on self-esteem boosts. We also investigated the correlates of liking versus wanting self-esteem boosts (and other pleasant rewards) on depression. A nationally representative sample of American adults (N = 867) indicated how much they liked and wanted several pleasant rewards (i.e., sex, food, alcohol, money, friendship, self-esteem boost). They also completed a standardized measure of depressive symptoms. As expected, there was a negative relationship between age and valuing self-esteem boosts, sex, and alcohol. People with depressive symptoms wanted self-esteem boosts, even though they did not like them very much. Similar effects were obtained for depressive symptoms and alcohol and friendship. This is the first research to show that self-esteem boosts are more valued among a nationally representative sample of younger American adults. It also is the first research to explore the association between depression and the motivation to boost self-esteem. People with depressive symptoms want self-esteem, and may pursue it, but this pursuit may feel unrewarding because they do not derive pleasure from it. © 2012 The Authors. Journal of Personality © 2012, Wiley Periodicals, Inc.

  13. 75 FR 80410 - Proposed Rules Governing Notification of Employee Rights Under the National Labor Relations Act

    Science.gov (United States)

    2010-12-22

    ... proposed rule, search ``documents open for comment'' and use key words such as ``National Labor Relations... their Beck rights. See footnote 5 above. In other words, existing law already requires notice of this.... Proposed Sec. 104.202(e) states that the Board will print the notice poster and provide copies to employers...

  14. Parasite stress and pathogen avoidance relate to distinct dimensions of political ideology across 30 nations

    Science.gov (United States)

    Tybur, Joshua M.; Inbar, Yoel; Aarøe, Lene; Barclay, Pat; Barlow, Fiona Kate; de Barra, Mícheál; Becker, D. Vaughn; Borovoi, Leah; Choi, Incheol; Choi, Jong An; Consedine, Nathan S.; Conway, Alan; Conway, Jane Rebecca; Conway, Paul; Adoric, Vera Cubela; Demirci, Dilara Ekin; Fernández, Ana María; Ferreira, Diogo Conque Seco; Ishii, Keiko; Jakšić, Ivana; Ji, Tingting; van Leeuwen, Florian; Lewis, David M. G.; Li, Norman P.; McIntyre, Jason C.; Mukherjee, Sumitava; Park, Justin H.; Pawlowski, Boguslaw; Petersen, Michael Bang; Pizarro, David; Prodromitis, Gerasimos; Prokop, Pavol; Rantala, Markus J.; Reynolds, Lisa M.; Sandin, Bonifacio; Sevi, Bariş; De Smet, Delphine; Srinivasan, Narayanan; Tewari, Shruti; Wilson, Cameron; Yong, Jose C.; Žeželj, Iris

    2016-01-01

    People who are more avoidant of pathogens are more politically conservative, as are nations with greater parasite stress. In the current research, we test two prominent hypotheses that have been proposed as explanations for these relationships. The first, which is an intragroup account, holds that these relationships between pathogens and politics are based on motivations to adhere to local norms, which are sometimes shaped by cultural evolution to have pathogen-neutralizing properties. The second, which is an intergroup account, holds that these same relationships are based on motivations to avoid contact with outgroups, who might pose greater infectious disease threats than ingroup members. Results from a study surveying 11,501 participants across 30 nations are more consistent with the intragroup account than with the intergroup account. National parasite stress relates to traditionalism (an aspect of conservatism especially related to adherence to group norms) but not to social dominance orientation (SDO; an aspect of conservatism especially related to endorsements of intergroup barriers and negativity toward ethnic and racial outgroups). Further, individual differences in pathogen-avoidance motives (i.e., disgust sensitivity) relate more strongly to traditionalism than to SDO within the 30 nations. PMID:27791090

  15. National Academic Award Winners over Time: Their Family Situation, Education and Interpersonal Relations

    Science.gov (United States)

    Sekowski, Andrzej; Siekanska, Malgorzata

    2008-01-01

    The article presents the results of a study focusing on the family situation, education and interpersonal relations of adults (26-35 years old) who in their adolescence (16-19 years old) displayed exceptional giftedness. One group of those surveyed were national academic award winners (90). The control group consisted of 90 people of no…

  16. Parasite stress and pathogen avoidance relate to distinct dimensions of political ideology across 30 nations.

    Science.gov (United States)

    Tybur, Joshua M; Inbar, Yoel; Aarøe, Lene; Barclay, Pat; Barlow, Fiona Kate; de Barra, Mícheál; Becker, D Vaughn; Borovoi, Leah; Choi, Incheol; Choi, Jong An; Consedine, Nathan S; Conway, Alan; Conway, Jane Rebecca; Conway, Paul; Adoric, Vera Cubela; Demirci, Dilara Ekin; Fernández, Ana María; Ferreira, Diogo Conque Seco; Ishii, Keiko; Jakšić, Ivana; Ji, Tingting; van Leeuwen, Florian; Lewis, David M G; Li, Norman P; McIntyre, Jason C; Mukherjee, Sumitava; Park, Justin H; Pawlowski, Boguslaw; Petersen, Michael Bang; Pizarro, David; Prodromitis, Gerasimos; Prokop, Pavol; Rantala, Markus J; Reynolds, Lisa M; Sandin, Bonifacio; Sevi, Bariş; De Smet, Delphine; Srinivasan, Narayanan; Tewari, Shruti; Wilson, Cameron; Yong, Jose C; Žeželj, Iris

    2016-11-01

    People who are more avoidant of pathogens are more politically conservative, as are nations with greater parasite stress. In the current research, we test two prominent hypotheses that have been proposed as explanations for these relationships. The first, which is an intragroup account, holds that these relationships between pathogens and politics are based on motivations to adhere to local norms, which are sometimes shaped by cultural evolution to have pathogen-neutralizing properties. The second, which is an intergroup account, holds that these same relationships are based on motivations to avoid contact with outgroups, who might pose greater infectious disease threats than ingroup members. Results from a study surveying 11,501 participants across 30 nations are more consistent with the intragroup account than with the intergroup account. National parasite stress relates to traditionalism (an aspect of conservatism especially related to adherence to group norms) but not to social dominance orientation (SDO; an aspect of conservatism especially related to endorsements of intergroup barriers and negativity toward ethnic and racial outgroups). Further, individual differences in pathogen-avoidance motives (i.e., disgust sensitivity) relate more strongly to traditionalism than to SDO within the 30 nations.

  17. Cross-National Perspectiveson Intergenerational Family Relations: The Influence of Public Policy Arrangements

    NARCIS (Netherlands)

    P.A. Dykstra (Pearl)

    2017-01-01

    textabstractFocusing mostly on Europe,this overview reveals how the research on cross-national differences in intergenerational family relations has movedfrombasic descriptions to a focus on understanding how support exchanges are shaped by macro-level processes.A key issue concerns generational

  18. Validation of non-formal and informal learning from a European perspective – linking validation arrangements with national qualifications frameworks

    Directory of Open Access Journals (Sweden)

    Borut Mikulec

    2015-12-01

    Full Text Available The paper analyses European policy on the validation of non-formal and informal learning, which is presented as a “salvation narrative” that can improve the functioning of the labour market, provide a way out from unemployment and strengthen the competitiveness of the economy. Taking as our starting point recent findings in adult education theory on the validation of non-formal and informal learning, we aim to prove the thesis that what European validation policy promotes is above all economic purpose and that it establishes a “Credential/Credit-exchange” model of validation of non-formal and informal learning. We proceed to ecxamine the effect of European VNIL policy in selected European countries where validation arrangements are linked to the qualifications framework. We find that the “Credential/ Credit-exchange” validation model was first established in a few individual European countries and then transferred, as a “successful” model, to the level of common European VNIL policy.

  19. Are we Europeans?: Correlates and the relation between national and European identity

    Directory of Open Access Journals (Sweden)

    Mihić Vladimir

    2009-01-01

    Full Text Available Researches of the correlates of the national identity are plentiful both in Serbian and foreign literature. However, in the past decade or so, a new social identity starts to make its way into the researches of the social psychologists-European identity or the sense of belonging to the Europe and the Europeans. This paper deals with the relation between national and European identity, as well as with the correlates of both of these, or one of them. The sample consisted of 451 subjects, all residents of major cities in the Vojvodina region (northern Serbia, divided into several categories-ethnicity (Serbs and Hungarians, educational level (primary and secondary school or University degree, gender and age. Several scales have been used: Cinnirela's national and European identity scale, Collective self-esteem scale, scale measuring attitudes towards the European integration-STEIN and Social dominance orientation scale-SDO. The questionnaire with the demographic characteristics has also been the part of the instrument. The research has been conducted in 2005 and 2006 in the all of the major Vojvodinian cities. Results show the relation between national and European identity is foggy, but general conclusion is that we can observe them as independent identities. The correlates of the national identity were ethnicity, high social dominance orientation, high collective self-esteem and negative attitude towards the European integrations. Correlates of the European identity were fewer: ethnicity, positive attitude towards the European integration and low social dominance orientation.

  20. Nation

    DEFF Research Database (Denmark)

    Østergaard, Uffe

    2014-01-01

    Nation er et gammelt begreb, som kommer af det latinske ord for fødsel, natio. Nationalisme bygger på forestillingen om, at mennesker har én og kun én national identitet og har ret til deres egen nationalstat. Ordet og forestillingen er kun godt 200 år gammel, og i 1900-tallet har ideologien bredt...

  1. The health-related, social, and economic consequences of parkinsonism: a controlled national study

    DEFF Research Database (Denmark)

    Jennum, Poul Jørgen; Assenholt, Maria Elizabeth Anna; Korbo, Lise

    2011-01-01

    Parkinson's disease (PD) and atypical parkinsonism (AP) cause a significant socioeconomic burden, but there is insufficient information about the total disease burden at a national level. Thus, the goal of this study was to estimate the excess direct and indirect costs of PD and AP in a national...... on income data derived from the Coherent Social Statistics. Patients with PD and AP had significantly higher rates of health-related contact and medication use and a higher socioeconomic cost. Furthermore, they had very low employment rates, and those in employment had a lower income level than employed...

  2. NATION-STATE COMING BACK ON THE SCENE OF INTERNATIONAL RELATIONS

    Directory of Open Access Journals (Sweden)

    Cristian Moisoiu

    2017-07-01

    Full Text Available This paper is trying to present the hypothesis of nation-state’s return as a relevant actor in foreign relations. Globalization, together with pax Americana, as a main nuclei of globalization, have extrapolated the idea of natural order and market economy, as it seemed that any discussion related to the role of state becomes obsolete. The recent events, with political and economic resonance, the market failures and instability, which required interventionist measures of the state for recovery and stability, major changes and trends of political spectrum, especially in the Western world have contradicted the prospect of natural order. Nevertheless, the discussion surrounding the role of state in economy, the invigoration of nation-state in international relations with possible future implications is regaining momentum.

  3. Examining gambling-related crime reports in the National Finnish Police Register.

    Science.gov (United States)

    Kuoppamäki, Sanna-Mari; Kääriäinen, Juha; Lind, Kalle

    2014-12-01

    The aim of this study is to examine the connection between gambling and criminal activity in the National Finnish Police Register. First, a method was created that enabled the search for gambling-related police reports in the National Finnish Police Register. The method is based on finding gambling-related police reports by using gambling-related headwords. Second, all police reports from 2011 that included any mention of gambling were read through (n = 2,233). Suspected gambling-related of crimes (n = 737) were selected from these reports. Those suspected gambling-related crimes were then described and categorized into six different categories: suspected online-related crimes; suspected crimes that were related to lifestyle-gaming; suspected crimes that involved a gambler as a victim of a crime; criminal activity related to problem gambling; casino-connected crimes, and intimate partnership violence resulting from gambling problems. This study, being the first in Finland, generated information on the connection between gambling and criminal activity from the perspective of police reports. Moreover, the study highlights methodological issues that are involved in studying police reports.

  4. Linked data management

    CERN Document Server

    Hose, Katja; Schenkel, Ralf

    2014-01-01

    Linked Data Management presents techniques for querying and managing Linked Data that is available on today’s Web. The book shows how the abundance of Linked Data can serve as fertile ground for research and commercial applications. The text focuses on aspects of managing large-scale collections of Linked Data. It offers a detailed introduction to Linked Data and related standards, including the main principles distinguishing Linked Data from standard database technology. Chapters also describe how to generate links between datasets and explain the overall architecture of data integration systems based on Linked Data. A large part of the text is devoted to query processing in different setups. After presenting methods to publish relational data as Linked Data and efficient centralized processing, the book explores lookup-based, distributed, and parallel solutions. It then addresses advanced topics, such as reasoning, and discusses work related to read-write Linked Data for system interoperation. Desp...

  5. Lessons learned from the management of a national outbreak of Salmonella ohio linked to pork meat processing and distribution.

    Science.gov (United States)

    Bertrand, Sophie; Dierick, Katelijne; Heylen, Kim; De Baere, Thierry; Pochet, Brigitte; Robesyn, Emmanuel; Lokietek, Sophie; Van Meervenne, Eva; Imberechts, Hein; De Zutter, Lieven; Collard, Jean-Marc

    2010-03-01

    During the summer of 2005, an increase in reports of human cases of Salmonella enterica serovar Ohio infection was observed in Belgium. During 11 weeks, between 1 July and 13 September, 60 cases of laboratory-confirmed Salmonella Ohio infection were reported to the National Reference Centre for Salmonella, with a peak onset of symptoms in the third week of July. All clinical isolates caused self-limiting gastroenteritis; both genders (32 males and 28 females) and all age groups (three children 65 years of age) were affected. The isolates were distributed throughout Belgium but a cluster of several cases was observed around Brussels. At the same time, an increase in the incidence of this serovar was observed in the Salmonella isolates originating from the official surveillance campaign conducted by the Federal Agency for the Safety of the Food Chain, which identified pork as a likely source of the outbreak strain. Pulsed-field gel electrophoresis typing confirmed the clonal relationship between the human isolates, the isolates from samples collected in the cutting plants, and the isolates from pork meat in distribution. Further epidemiological investigations indicated that one particular slaughterhouse was involved. In that slaughterhouse, the carcasses were contaminated during the evisceration process because of contaminated equipment and uncontrolled environmental conditions. This study highlights the importance of a centralized surveillance laboratory in the management of outbreaks and the need of strict implementation of hygienic rules to avoid this type of outbreak.

  6. Hungarian national report on activities related to operator support systems for nuclear power plants

    International Nuclear Information System (INIS)

    Adorjan, F.; Lux, I.; Vegh, J.; Vegh, E.

    1993-01-01

    According to the summary report of the Co-ordinated Research Meeting on ''Operator Support Systems in Nuclear Power Plants'', 13-16 October 1992, the national reports shall cover the following topics: General summary of the national activity; description of the results in the framework of the CRP; overview of the OSS related recent national activity. Accordingly, in the first section we give an overview of the operator support systems developed in Hungary. The second section summarizes the data collected in order to comply with the Tasks 4.1.1 and 4.1.2 of the CRP. In the third section we summarize the most recent works pertaining to the development and application of OSS at nuclear power plants

  7. The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases.

    Science.gov (United States)

    Mukherjee, Mome; Stoddart, Andrew; Gupta, Ramyani P; Nwaru, Bright I; Farr, Angela; Heaven, Martin; Fitzsimmons, Deborah; Bandyopadhyay, Amrita; Aftab, Chantelle; Simpson, Colin R; Lyons, Ronan A; Fischbacher, Colin; Dibben, Christopher; Shields, Michael D; Phillips, Ceri J; Strachan, David P; Davies, Gwyneth A; McKinstry, Brian; Sheikh, Aziz

    2016-08-29

    There are a lack of reliable data on the epidemiology and associated burden and costs of asthma. We sought to provide the first UK-wide estimates of the epidemiology, healthcare utilisation and costs of asthma. We obtained and analysed asthma-relevant data from 27 datasets: these comprised national health surveys for 2010-11, and routine administrative, health and social care datasets for 2011-12; 2011-12 costs were estimated in pounds sterling using economic modelling. The prevalence of asthma depended on the definition and data source used. The UK lifetime prevalence of patient-reported symptoms suggestive of asthma was 29.5 % (95 % CI, 27.7-31.3; n = 18.5 million (m) people) and 15.6 % (14.3-16.9, n = 9.8 m) for patient-reported clinician-diagnosed asthma. The annual prevalence of patient-reported clinician-diagnosed-and-treated asthma was 9.6 % (8.9-10.3, n = 6.0 m) and of clinician-reported, diagnosed-and-treated asthma 5.7 % (5.7-5.7; n = 3.6 m). Asthma resulted in at least 6.3 m primary care consultations, 93,000 hospital in-patient episodes, 1800 intensive-care unit episodes and 36,800 disability living allowance claims. The costs of asthma were estimated at least £1.1 billion: 74 % of these costs were for provision of primary care services (60 % prescribing, 14 % consultations), 13 % for disability claims, and 12 % for hospital care. There were 1160 asthma deaths. Asthma is very common and is responsible for considerable morbidity, healthcare utilisation and financial costs to the UK public sector. Greater policy focus on primary care provision is needed to reduce the risk of asthma exacerbations, hospitalisations and deaths, and reduce costs.

  8. Linking well-being with cultural revitalization for greater cognitive justice in conservation: lessons from Venezuela in Canaima National Park

    Directory of Open Access Journals (Sweden)

    Iokiñe Rodriguez

    2017-12-01

    Full Text Available Across the globe, conservation policies have often suppressed nonscientific forms of knowledge and ways of knowing nature, along with the social practices of the groups that are informed by such knowledge. Reversing this process of epistemic supremacy is crucial both for achieving greater cognitive justice in conservation areas and ensuring that conservation aims are achieved. Doing so, however, is not an easy task. In situations of cultural violence, hidden environmental knowledge is not easily made visible unless adequate conditions for it to emerge are created. I show that one way forward is by conservation engaging with the well-being agendas of indigenous people, in particular, with the construction of their life plans. This discussion is illustrated through a case study in Canaima National Park, Venezuela, where over the last 20 years, social-ecological research has been studying existing conflicts over the use of fire while supporting the development of Pemon (the indigenous peoples in this area Life Plans. Assisting in the development of life plans through participatory historical reconstructions, territorial self-demarcation processes, and facilitation of community reflexivity about its social-ecological changes and desired future has been decisive for the Pemon, and has revealed fire management knowledge that challenges conventional explanations of landscape change that simplistically place the blame for such changes on the local use of fire. This local knowledge, combined with results from studies of Pemon fire regimes, fire behavior ecology, and paleoecological research, now informs a counter narrative of landscape change that is influencing a shift in environmental discourse and policy-making toward an intercultural fire management approach. By documenting how social-ecological research has engaged with the Pemon Life Plan processes, I show the important role that cultural revitalization plays in making hidden and silenced local

  9. Irregular menses linked to vomiting in a nonclinical sample: findings from the National Eating Disorders Screening Program in high schools.

    Science.gov (United States)

    Austin, S Bryn; Ziyadeh, Najat J; Vohra, Sameer; Forman, Sara; Gordon, Catherine M; Prokop, Lisa A; Keliher, Anne; Jacobs, Douglas

    2008-05-01

    Using data from an eating disorders screening initiative conducted in high schools across the United States, we examined the relationship between vomiting frequency and irregular menses in a nonclinical sample of adolescent females. A self-report questionnaire was administered to students from U.S. high schools participating in the National Eating Disorders Screening Program in 2000. The questionnaire included items on frequency of vomiting for weight control in the past 3 months, other eating disorder symptoms, frequency of menses, height, and weight. Multivariable regression analyses were conducted using data from 2791 girls to estimate the risk of irregular menses (defined as menses less often than monthly) associated with vomiting frequency, adjusting for other eating disorder symptoms, weight status, age, race/ethnicity, and school clusters. Girls who vomited to control their weight one to three times per month were one and a half times more likely (risk ratio [RR] = 1.6; 95% confidence interval [CI] = 1.2-2.2), and girls who vomited once per week or more often were more than three times more likely (RR = 3.2; 95% CI = 2.3-4.4), to experience irregular menses than were girls who did not report vomiting for weight control. Vomiting for weight control remained a strong predictor of irregular menses even when overweight and underweight participants were excluded. Our study adds to the evidence that vomiting may have a direct effect on hormonal function in adolescent girls, and that vomiting for weight control may be a particularly deleterious component of eating disorders.

  10. Bioanalysis-related highlights from the 2011 AAPS National Biotechnology Conference.

    Science.gov (United States)

    Crisino, Rebecca M; Dulanto, Beatriz

    2011-08-01

    The American Association of Pharmaceutical Scientists is a dynamic international forum for the exchange of knowledge among scientists to enhance their contributions to drug development. The annual National Biotechnology Conference, conducted and organized by the American Association of Pharmaceutical Scientists, is a forum dedicated to advancements in science and technology related to discovery, development and manufacture of medical biotechnology products. The 2011 National Biotechnology Conference meeting convened in San Francisco, CA, USA on 16-18 May. Over 300 abstracts were submitted and approximately 50 sessions examined topics pertaining to advances in drug development, emerging analytical technologies, bioanalysis-related issues, biosimilar therapies, updates on global regulatory documents and expectations, and other topics. The focus of this article is to highlight key developments relevant to immunogenicity and pharmacokinetic drug concentration bioanalysis.

  11. Linking National Parks with its Gateway Communities for Tourism Development in Central America: Nindiri, Nicaragua, Bagazit, Costa Rica and Portobelo, Panama

    Directory of Open Access Journals (Sweden)

    Aguirre G., J. A.

    2006-01-01

    Full Text Available Protected areas and national parks are becoming one of the most important forms of land use in Central America. All the projections made by the World Tourism Organization seems to agree that by 2010 Central America, maybe receiving between eight and ten millions tourists, a figure that is almost twice what the region is receiving today. A study was conducted base on 369 direct field surveys conducted in three Central American communities: Bagazit gateway community to Palo Verde National Park, Costa Rica, Nindiri, gateway community to Volcan Masaya National Park, Nicaragua and Portobelo, gateway community to Por-tobelo National Park, Panama. The study found that relative to the socio-demographic variables, that there were no significance differences at the 95% probability level in all four variables, age, sex, education and monthly income of the family. Educational level seems to be the socio-demographic variables affecting more the state of relations. The perception variable being has taken into account in the decision that affects the communities and responsibility to help with community problems are present in two of the three models. The perception variables related to tourism, feel trained to take care of the tourist and existence of businesses that can caters to tourist seem to be key elements in the community perception about the state of relation. Tourism related economic activities and community participation in park decisions are today and will be in the future essential elements in the shaping of community/park relations in Central America as tourism becomes a major economic sector in the region economy.

  12. Activation of a PGC-1-related Coactivator (PRC)-dependent Inflammatory Stress Program Linked to Apoptosis and Premature Senescence*

    Science.gov (United States)

    Gleyzer, Natalie; Scarpulla, Richard C.

    2013-01-01

    PGC-1-related coactivator (PRC), a growth-regulated member of the PGC-1 coactivator family, contributes to the expression of the mitochondrial respiratory apparatus. PRC also orchestrates a robust response to metabolic stress by promoting the expression of multiple genes specifying inflammation, proliferation, and metabolic reprogramming. Here, we demonstrate that this PRC-dependent stress program is activated during apoptosis and senescence, two major protective mechanisms against cellular dysfunction. Both PRC and its targets (IL1α, SPRR2D, and SPRR2F) were rapidly induced by menadione, an agent that promotes apoptosis through the generation of intracellular oxidants. Menadione-induced apoptosis and the PRC stress program were blocked by the antioxidant N-acetylcysteine. The PRC stress response was also activated by the topoisomerase I inhibitor 7-ethyl-10-hydroxycamptothecin (SN-38), an inducer of premature senescence in tumor cells. Cells treated with SN-38 displayed morphological characteristics of senescence and express senescence-associated β-galactosidase activity. In contrast to menadione, the SN-38 induction of the PRC program occurred over an extended time course and was antioxidant-insensitive. The potential adaptive function of the PRC stress response was investigated by treating cells with meclizine, a drug that promotes glycolytic energy metabolism and has been linked to cardio- and neuroprotection against ischemia-reperfusion injury. Meclizine increased lactate production and was a potent inducer of the PRC stress program, suggesting that PRC may contribute to the protective effects of meclizine. Finally, c-MYC and PRC were coordinately induced under all conditions tested, implicating c-MYC in the biological response to metabolic stress. The results suggest a general role for PRC in the adaptive response to cellular dysfunction. PMID:23364789

  13. Possible Link Between Stress-related Factors and Altered Body Composition in Women with Polycystic Ovarian Syndrome.

    Science.gov (United States)

    Basu, Barnali Ray; Chowdhury, Olivia; Saha, Sudip Kumar

    2018-01-01

    Stress is an invisible factor affecting modern day living and is strongly associated with many disease pathogenesis including polycystic ovarian syndrome (PCOS) in women. PCOS is the most frequent endocrinological disorder that affects women of reproductive age, leading to metabolic dysfunction and body composition alterations. Salivary amylase and cortisol are major stress mediators that have been implicated in PCOS. However, their role in altering body composition in PCOS is yet to be deciphered. The present study aimed at understanding the relation between stress-associated factors and alterations in body composition among PCOS patients. This study enrolled a total of 100 patients (PCOS) and 60 age-matched controls. The female patients were of ages between 13 and 30 years. Standard assay kits were used to evaluate the α-amylase activity and cortisol level in saliva. The participants were chosen on the basis of the Rotterdam American Society for Reproductive Medicine/European Society of Human Reproduction criteria. Saliva was collected from each participant as per the protocol of Salimetrics, USA. Statistical analysis was performed using SPSS version 20 for Windows. The quantitative variables are described as mean ± standard deviation. P stress scenario in their system. Moreover, overweight PCOS participants reflected higher amylase activity than the lean patients participants. Pulse rate, body mass index (BMI), visceral adiposity, and waist-hip ratio (WHR) was considerably higher in the PCOS patients participants compared to controls. A significant correlation could be drawn between the α-amylase activity and BMI or WHR, respectively, among PCOS patients. These observations indicate a strong link between the stress marker and alterations in the body composition parameters of PCOS patients participants. Higher prevalence of stress in PCOS patients participants has a critical role in their altered body composition.

  14. The associations between nationality, fertility history and diabetes-related mortality: a retrospective cohort study in the Brussels-Capital Region (2001-2005).

    Science.gov (United States)

    Vandenheede, Hadewijch; Deboosere, Patrick; Gadeyne, Sylvie; De Spiegelaere, Myriam

    2012-03-01

    The relationship between women's parity and diabetes mortality has been investigated in several studies, with mixed results. This study aims to establish if parity and age at first birth are associated with diabetes-related mortality and if these factors contribute to variations in diabetes-related mortality among women with different nationalities. Data of the 2001 census are linked to registration records of all deaths and emigrations (period 2001-2005). The study population comprises all female inhabitants of the Brussels-Capital Region aged 45-74 of either Belgian or North African nationality (n = 108 296). Age-standardized mortality rates (direct standardization) and mortality rate ratios (Poisson's regression) are computed. Both parity and age at first birth are associated with diabetes-related mortality. Highest risks of dying from diabetes are observed among grandmultiparous women and teenage mothers. Differences in diabetes-related mortality according to nationality are observed. Age-standardized diabetes mortality rates are higher in North African [ASMR = 417.4/100,000; 95% confidence interval (CI) 227.2-607.7] than in Belgian women (ASMR = 184.0/100,000; 95% CI 157.3-210.8). Taking parity, age at first birth and education into account, these differences largely disappear. Reproductive factors are associated with diabetes-related mortality and play an important part in the higher diabetes-related mortality of North African compared with Belgian women.

  15. Urban national parks in the global South: Linking management perceptions, policies and practices to water-related ecosystem services

    CSIR Research Space (South Africa)

    Brill, G

    2017-12-01

    Full Text Available systems. Protected areas are now considered part of a broader social, cultural and social-economic landscape and management approaches need to incorporate social-ecological systems (SES) thinking....

  16. Possible link between stress-related factors and altered body composition in women with polycystic ovarian syndrome

    Directory of Open Access Journals (Sweden)

    Barnali Ray Basu

    2018-01-01

    Full Text Available Background: Stress is an invisible factor affecting modern day living and is strongly associated with many disease pathogenesis including polycystic ovarian syndrome (PCOS in women. PCOS is the most frequent endocrinological disorder that affects women of reproductive age, leading to metabolic dysfunction and body composition alterations. Salivary amylase and cortisol are major stress mediators that have been implicated in PCOS. However, their role in altering body composition in PCOS is yet to be deciphered. Aim: The present study aimed at understanding the relation between stress-associated factors and alterations in body composition among PCOS patients. Design: This study enrolled a total of 100 patients (PCOS and 60 age-matched controls. The female patients were of ages between 13 and 30 years. Materials and Methods: Standard assay kits were used to evaluate the α-amylase activity and cortisol level in saliva. The participants were chosen on the basis of the Rotterdam American Society for Reproductive Medicine/European Society of Human Reproduction criteria. Saliva was collected from each participant as per the protocol of Salimetrics, USA. Statistical Analysis: Statistical analysis was performed using SPSS version 20 for Windows. The quantitative variables are described as mean ± standard deviation. P < 0.05 was considered significant. Results: Increased salivary cortisol level and α-amylase activity were seen in the PCOS population as compared to age-matched controls suggesting patients a sustained stress scenario in their system. Moreover, overweight PCOS participants reflected higher amylase activity than the lean patients participants. Pulse rate, body mass index (BMI, visceral adiposity, and waist-hip ratio (WHR was considerably higher in the PCOS patients participants compared to controls. A significant correlation could be drawn between the α-amylase activity and BMI or WHR, respectively, among PCOS patients. These observations

  17. Missing rings in Pinus halepensis – the missing link to relate the tree-ring record to extreme climatic events

    Directory of Open Access Journals (Sweden)

    Klemen eNovak

    2016-05-01

    Full Text Available Climate predictions for the Mediterranean Basin include increased temperatures, decreased precipitation, and increased frequency of extreme climatic events (ECE. These conditions are associated with decreased growth of trees and their increased vulnerability to pests and diseases. The anatomy of tree rings is responsive to these environmental conditions. Quantitatively, the width of a tree ring is largely determined by the rate and duration of cell division by the vascular cambium. In the Mediterranean climate, cambial cell division may occur throughout almost the entire year. Alternatively, cell division may stop during relatively cool and dry winters, only to resume in the same year with milder temperatures and increased availability of water. Under particularly adverse conditions, no xylem may be produced in parts of the stem, resulting in a missing ring (MR, which can link tree-ring anatomy to the occurrence of extreme events. A dendrochronological network of Pinus halepensis, a widespread tree species in the Mediterranean basin, was used to determine the relationship of MR to ECE. The network consisted of 113 sites throughout its distribution range. Binomial logistic regression analysis of 2595 MR series determined that MR increased in frequency with increased cambial age. Spatial analysis indicated that the geographic areas of southeastern Spain and northern Algeria contained the greatest frequency of MR. Further regression analysis indicated that the relationship of MR to total monthly precipitation and mean temperature was non-linear. In this first determination of climatic influences on MR, the formation of MR was most strongly associated with the combination of monthly mean temperature above 10°C from previous October till current February and total precipitation below 50 mm from previous September till current May. This conclusion is global and can be applied to every site across the distribution area. Rather than simply being a

  18. MgADP-induced changes in the structure of myosin S1 near the ATPase-related thiol SH1 probed by cross-linking

    International Nuclear Information System (INIS)

    Rajasekharan, K.N.; Mayadevi, M.; Agarwal, R.; Burke, M.

    1990-01-01

    The structural consequence of MgADP binding at the vicinity of the ATPase-related thiol SH1 (Cys-707) have been examined by subjecting myosin subfragment 1, premodified at SH2 (Cys-697) with N-ethylmaleimide (NEM), to reaction with the bifunctional reagent p-phenylenedimaleimide (pPDM) in the presence and absence of MgADP. By monitoring the changes in the Ca 2+ -ATPase activity as a function of reaction time, it appears that the reagent rapidly modifies SH1 irrespective of whether MgADP is present or not. In the absence of nucleotide, only extremely low levels of cross-linking to the 50-kDa middle segment of S1 can be detected, while in the presence of MgADP substantial cross-linking to this segment is observed. A similar cross-link is also formed if MgADP is added subsequent to the reaction of the SH2-NEM-premodified S1 with pPDM in the absence of nucleotide. Isolation of the labeled tryptic peptide from the cross-linked adduct formed with [ 14 C]pPDM, and subsequent partial sequence analyses, indicates that the cross-link is made from SH1 to Cys-522. Moreover, it appears that this cross-link results in the trapping of MgADP in this S1 species. These data suggest that the binding of MgADP results in a change in the structure of S1 in the vicinity of the SH1 thiol relative to the 50-kDa domain which enables Cys-522 to adopt the appropriate configuration to enable it to be cross-linked to SH1 by pPDM

  19. Impact of Weight of the Nation Community Screenings on Obesity-Related Beliefs

    Science.gov (United States)

    Luecking, Courtney T.; Noar, Seth M.; Dooley, Rachel M.; Gizlice, Ziya; Ammerman, Alice S.

    2017-01-01

    Introduction HBO’s Weight of the Nation was a collaborative effort among several national organizations to raise awareness about the complexity of the obesity epidemic and promote action through media and community forums. The primary aim of this study was to assess the short-term effects of Weight of the Nation community screenings on obesity-related beliefs, intentions, and policy support. Methods Five Prevention Research Centers across the U.S. administered surveys at nine Weight of the Nation community screenings between September 2012 and May 2013. Adults aged ≥18 years who completed pre–post surveys were included. The survey assessed demographic information, perceptions of the documentary, efficacy to take action and influence policies that affect obesity, intentions to take actions to support a healthy weight, and positions on policy changes that impact food systems. Data were analyzed in 2015. Results A convenience sample of 442 individuals completed surveys. The sample was mostly health workers, female, college educated, aged 25–44 years, and racially and ethnically diverse. Significant increases (p<0.001) were observed for perceived self- and collective efficacy that individuals and communities can influence policies and environmental factors that affect obesity, intentions to take actions that contribute to a healthy weight, and support for policies that change the food system. Conclusions A broad, nationwide effort, such as Weight of the Nation, that combines media with opportunities to bring community members together for discussion, may play a role in influencing beliefs, intentions, and policy support regarding obesity prevention. PMID:28215388

  20. Links between Local Language Competence and Peer Relations among Swiss and Immigrant Children: The Mediating Role of Social Behavior

    Science.gov (United States)

    von Grunigen, Renate; Kochenderfer-Ladd, Becky; Perren, Sonja; Alsaker, Francoise D.

    2012-01-01

    The primary aim of this investigation was to evaluate a model in which children's social behaviors, including prosocial behavior, setting limits, and social withdrawal, were hypothesized to mediate the links between local language competence (LLC) and peer acceptance and victimization. Longitudinal data were collected via teacher and peer reports…

  1. 45 CFR 2526.60 - May an individual receive an education award and related interest benefits from the National...

    Science.gov (United States)

    2010-10-01

    ... an individual receive an education award and related interest benefits from the National Service... education award and related interest benefits from the National Service Trust for a term of service and have... 45 Public Welfare 4 2010-10-01 2010-10-01 false May an individual receive an education award and...

  2. THE EFFECTS OF NATIONAL SCIENTIFIC STYLE ON THE UNDERSTANDING OF SCIENTIFIC INNOVATION--SPECIAL RELATIVITY, A CASE HISTORY. FINAL REPORT.

    Science.gov (United States)

    GOLDBERG, STANLEY

    COMPARED ARE THE RESPONSES TO EINSTEIN'S THEORY OF RELATIVITY IN FOUR COUNTRIES BETWEEN THE YEARS 1905 AND 1911. THE COUNTRIES STUDIED ARE GERMANY, FRANCE, ENGLAND, AND THE UNITED STATES. ON THE BASIS OF THE RESPONSE, NATIONAL SCIENTIFIC STYLES ARE IDENTIFIED, AND THESE STYLES ARE RELATED TO PREVIOUS NATIONAL CHARACTERISTICS OF DOING SCIENCE AND…

  3. European Lifelong Guidance Policy Network Representatives' Conceptions of the Role of Information and Communication Technologies Related to National Guidance Policies

    Science.gov (United States)

    Kettunen, Jaana; Vuorinen, Raimo; Ruusuvirta, Outi

    2016-01-01

    This article reports findings from a phenomenographic investigation into European Lifelong Guidance Policy Network representatives' conceptions of the role of information and communication technologies (ICT) related to national lifelong guidance policies. The role of ICT in relation to national lifelong guidance policies was conceived as (1)…

  4. The topology of inter-industry relations from the Portuguese national accounts

    Science.gov (United States)

    Araújo, Tanya; Faustino, Rui

    2017-08-01

    In last years, the Portuguese economy has gone through a severe adjustment process, affecting almost all industrial sectors, the building blocks of economic structures. Research on economic structural changes has made use of input/output tables to define networks of industrial relations. Here, these networks are induced from output tables of the Portuguese national accounting system, being each inter-industry relation defined by the output made by any two industries for the products that they both produce. The topological analysis of these networks allows to uncover a particular structure that comes out during the Portuguese adjustment program. The evolution of the industrial networks shows an important structural change in 2011-2014, confirming the usefulness of inducting similarity networks from output tables and the consequent promising power of the graph formulation for the analysis of inter-industry relations.

  5. Spent fuel reprocessing and minor actinide partitioning safety related research at the UK National Nuclear Laboratory

    International Nuclear Information System (INIS)

    Carrott, Michael; Flint, Lauren; Gregson, Colin; Griffiths, Tamara; Hodgson, Zara; Maher, Chris; Mason, Chris; McLachlan, Fiona; Orr, Robin; Reilly, Stacey; Rhodes, Chris; Sarsfield, Mark; Sims, Howard; Shepherd, Daniel; Taylor, Robin; Webb, Kevin; Woodall, Sean; Woodhead, David

    2015-01-01

    The development of advanced separation processes for spent nuclear fuel reprocessing and minor actinide recycling is an essential component of international R and D programmes aimed at closing the nuclear fuel cycle around the middle of this century. While both aqueous and pyrochemical processes are under consideration internationally, neither option will gain broad acceptance without significant advances in process safety, waste minimisation, environmental impact and proliferation resistance; at least when compared to current reprocessing technologies. The UK National Nuclear Laboratory (NNL) is developing flowsheets for innovative aqueous separation processes. These include advanced PUREX options (i.e. processes using tributyl phosphate as the extractant for uranium, plutonium and possibly neptunium recovery) and GANEX (grouped actinide extraction) type processes that use diglycolamide based extractants to co-extract all transuranic actinides. At NNL, development of the flowsheets is closely linked to research on process safety, since this is essential for assessing prospects for future industrialisation and deployment. Within this context, NNL is part of European 7. Framework projects 'ASGARD' and 'SACSESS'. Key topics under investigation include: hydrogen generation from aqueous and solvent phases; decomposition of aqueous phase ligands used in separations prior to product finishing and recycle of nitric acid; dissolution of carbide fuels including management of organics generated. Additionally, there is a strong focus on use of predictive process modelling to assess flowsheet sensitivities as well as engineering design and global hazard assessment of these new processes. (authors)

  6. Breast Cancer Survivors Report Similar Concerns Related to Return to Work in Developed and Developing Nations.

    Science.gov (United States)

    Luo, Shi-Xiang; Liu, Jun-E; Cheng, Andy S K; Xiao, Shu-Qin; Su, Ya-Li; Feuerstein, Michael

    2018-02-14

    Aim To determine whether breast cancer survivors (BCS) at work following the diagnosis and/or treatment of breast cancer, in a rapidly developing country such as China experience similar to return to work challenges as reported in nations with established return to work (RTW) policy and procedures for employees with cancer. Methods Semi-structured interviews were conducted with 16 BCS who returned to work following diagnosis and/or primary cancer treatment. An Interpretative Phenomenological Analysis was used to investigate responses. Results Three recurring themes emerged: (1) challenges at work related to residual effects of diagnosis and/or primary treatment; (2) positive and negative responses from employers and/or supervisors; and (3) positive and negative responses from co-workers/colleagues. Although several participants experienced a high level of workplace support, there was a subgroup that did report challenges related to symptom burden, cognitive limitations, and both positive and negative responses by employers and co-workers were reported. Conclusions Findings indicate similar challenges in BCS who RTW during and/or following cancer treatment in both rapidly developing and developed nations. Results suggest that regardless of the existence of workplace policies and practices related to RTW for workers with a history of cancer, a subgroup of BCS experience similar challenges when returning to work. These findings highlight the international nature of RTW challenges and suggest the need for more global efforts to develop and evaluate workplace interventions to assist with these similarities.

  7. The influence of distance and level of care on delivery place in rural Zambia: a study of linked national data in a geographic information system.

    Directory of Open Access Journals (Sweden)

    Sabine Gabrysch

    Full Text Available BACKGROUND: Maternal and perinatal mortality could be reduced if all women delivered in settings where skilled attendants could provide emergency obstetric care (EmOC if complications arise. Research on determinants of skilled attendance at delivery has focussed on household and individual factors, neglecting the influence of the health service environment, in part due to a lack of suitable data. The aim of this study was to quantify the effects of distance to care and level of care on women's use of health facilities for delivery in rural Zambia, and to compare their population impact to that of other important determinants. METHODS AND FINDINGS: Using a geographic information system (GIS, we linked national household data from the Zambian Demographic and Health Survey 2007 with national facility data from the Zambian Health Facility Census 2005 and calculated straight-line distances. Health facilities were classified by whether they provided comprehensive EmOC (CEmOC, basic EmOC (BEmOC, or limited or substandard services. Multivariable multilevel logistic regression analyses were performed to investigate the influence of distance to care and level of care on place of delivery (facility or home for 3,682 rural births, controlling for a wide range of confounders. Only a third of rural Zambian births occurred at a health facility, and half of all births were to mothers living more than 25 km from a facility of BEmOC standard or better. As distance to the closest health facility doubled, the odds of facility delivery decreased by 29% (95% CI, 14%-40%. Independently, each step increase in level of care led to 26% higher odds of facility delivery (95% CI, 7%-48%. The population impact of poor geographic access to EmOC was at least of similar magnitude as that of low maternal education, household poverty, or lack of female autonomy. CONCLUSIONS: Lack of geographic access to emergency obstetric care is a key factor explaining why most rural deliveries

  8. The influence of distance and level of care on delivery place in rural Zambia: a study of linked national data in a geographic information system.

    Science.gov (United States)

    Gabrysch, Sabine; Cousens, Simon; Cox, Jonathan; Campbell, Oona M R

    2011-01-25

    Maternal and perinatal mortality could be reduced if all women delivered in settings where skilled attendants could provide emergency obstetric care (EmOC) if complications arise. Research on determinants of skilled attendance at delivery has focussed on household and individual factors, neglecting the influence of the health service environment, in part due to a lack of suitable data. The aim of this study was to quantify the effects of distance to care and level of care on women's use of health facilities for delivery in rural Zambia, and to compare their population impact to that of other important determinants. Using a geographic information system (GIS), we linked national household data from the Zambian Demographic and Health Survey 2007 with national facility data from the Zambian Health Facility Census 2005 and calculated straight-line distances. Health facilities were classified by whether they provided comprehensive EmOC (CEmOC), basic EmOC (BEmOC), or limited or substandard services. Multivariable multilevel logistic regression analyses were performed to investigate the influence of distance to care and level of care on place of delivery (facility or home) for 3,682 rural births, controlling for a wide range of confounders. Only a third of rural Zambian births occurred at a health facility, and half of all births were to mothers living more than 25 km from a facility of BEmOC standard or better. As distance to the closest health facility doubled, the odds of facility delivery decreased by 29% (95% CI, 14%-40%). Independently, each step increase in level of care led to 26% higher odds of facility delivery (95% CI, 7%-48%). The population impact of poor geographic access to EmOC was at least of similar magnitude as that of low maternal education, household poverty, or lack of female autonomy. Lack of geographic access to emergency obstetric care is a key factor explaining why most rural deliveries in Zambia still occur at home without skilled care

  9. The role of the National INIS Center in presenting Macedonian nuclear and nuclear related sciences

    International Nuclear Information System (INIS)

    Sejmenova-Gichevska, Marija

    2007-01-01

    The Republic of Macedonia is 95th Member State of INIS and its participation in this cooperative decentralized system started in 1996 when the Macedonian INIS Center was established to be operated by the National and University Library 'Kliment Ohridski' in Skopje. The main objective of this study is to give an overview of the Macedonian nuclear and nuclear related scientific thought presented in the INIS Database. A statistical analysis of the Macedonian INIS Center's contribution to the INIS Database for the period of its constitution to 2006, by quantifying and reviewing the language, publication type and INIS subject categories of the submitted records is presented. (author)

  10. Proposed national strategies for the prevention of leading work-related diseases and injuries. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    Preliminary strategies developed at the National Symposium on the Prevention of Leading Work Related Diseases and Injuries, held in Atlanta, Georgia on May 1 to 3, 1985 were revised, elaborated, and further developed. Strategies were developed for the prevention of occupational lung diseases, musculoskeletal injuries, occupational cancers, severe occupational traumatic injuries, and occupational cardiovascular diseases. Lung diseases considered included silicosis, asbestosis, lung cancer mesothelioma, coal workers' pneumoconiosis, byssinosis, occupational asthma, hypersensitivity pneumonitis, asphyxiation, irritation, pulmonary edema, brucellosis, psitticosis, anthrax, mycobacterioses, histoplasmosis, aspergillosis, and coccidioidomycosis. Occupational cancers were discussed as they occur in the lung, pleura, peritoneum, bladder, kidneys, blood, nasal cavity, skin, nasal sinuses, and liver.

  11. The health-related, social, and economic consequences of parkinsonism: a controlled national study

    DEFF Research Database (Denmark)

    Zoetmulder, Marielle

    2011-01-01

    on income data derived from the Coherent Social Statistics. Patients with PD and AP had significantly higher rates of health-related contact and medication use and a higher socioeconomic cost. Furthermore, they had very low employment rates, and those in employment had a lower income level than employed...... sample. Using records from the Danish National Patient Registry (1997-2007), 13,400 PD and 647 AP patients were identified and compared with, respectively, 53,600 and 2,588 control cases randomly selected with respect to age, gender, civil status, and geographic location. Direct costs including....../$1,165), respectively. The employment- and health-related consequences could be identified up to 8 years before the first diagnosis and increased with disease advancement. PD and AP have major socioeconomic consequences for patients and society. The health effects are present for up to more than 8 years before...

  12. Laterality related to the successive selection of Dutch national youth soccer players.

    Science.gov (United States)

    Verbeek, Jan; Elferink-Gemser, Marije T; Jonker, Laura; Huijgen, Barbara C H; Visscher, Chris

    2017-11-01

    In the general population, estimates of left-foot preference are around 20%. In soccer, specific tasks create positional demands, requiring 40% of the players to be left-footed. Whether and how this is related to the selection of players is unknown. To examine the successive selection of soccer players for Dutch national youth teams in relation to foot preference, 280 youth players (age = 16.2 ± 1.08 years) were monitored from the U16 through the U19 teams over the last 5 years. No difference in successive selection between left- and right-footed players was found (p soccer teams.

  13. [UNHEALTHY FOOD INTAKE IS LINKED TO HIGHER PREVALENCE OF METABOLIC SYNDROME IN CHILEAN ADULT POPULATION: CROSS SECTIONAL STUDY IN 2009-2010 NATIONAL HEALTH SURVEY].

    Science.gov (United States)

    Dussaillant, Catalina; Echeverría, Guadalupe; Villarroel, Luis; Marin, Pedro Paulo; Rigotti, Attilio

    2015-11-01

    metabolic syndrome (MS) is a clustering of risk factors known to promote cardiovascular disease and diabetes. Environmental factors, such as unhealthy diet, play a major role in the development of this condition. In this study, we evaluated the prevalence of MS and its association with food intake quality among Chilean adults. we analyzed data of 2 561 adults (≥ 18 years-old) included in the last National Health Survey (NHS 2009-2010) who had appropriate information to diagnose MS based on ATP III-NCEP guidelines. Consumption frequency of fish, whole grains, dairy, fruits and vegetables was also analyzed and associated with MS prevalence. Using a healthy diet score (HDS), we described the overall diet quality and further correlated it with MS prevalence. we found that lower whole grain intake was associated with greater MS prevalence (OR = 1.78; 95% CI: 1.088-2.919; p = 0.022). HDS showed better diet quality among women and in subjects with increasing age and higher educational level. A HDS Chilean adult population exhibits a high prevalence of MS linked to a poor diet quality. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  14. Investigation and Analysis on the Construction Situation of “Three Links and Two Platforms” of Education for Nationalities in Yunnan Province in China

    OpenAIRE

    Zhilin Zhao; Jianhou Gan

    2017-01-01

    “Three Links and Two Platforms”, which refers to schools links to ICTs, high-quality resource of class links to ICTs, people links to ICTs, public service platform for educational resources and public service platform for educational management, has played a crucial role in improving the educational equality in minority areas in Yunnan province and in realizing the sharing of high-quality educational resources. This research mainly adopts method of document investigation, which has investigat...

  15. Asbestos-related occupational cancers compensated under the Spanish National Insurance System, 1978-2011.

    Science.gov (United States)

    García-Gómez, Montserrat; Menéndez-Navarro, Alfredo; López, Rosario Castañeda

    2015-01-01

    In 1978, asbestos-related occupational cancers were added to the Spanish list of occupational diseases. However, there are no full accounts of compensated cases since their inclusion. To analyze the cases of asbestos-related cancer recognized as occupational in Spain between 1978 and 2011. Cases were obtained from the Spanish Employment Ministry. Specific incidence rates by year, economic activity, and occupation were obtained. We compared mortality rates of mesothelioma and bronchus and lung cancer mortality in Spain and the European Union. Between 1978 and 2011, 164 asbestos-related occupational cancers were recognized in Spain, with a mean annual rate of 0·08 per 10(5) employees (0·13 in males, 0·002 in females). Under-recognition rates were an estimated 93·6% (males) and 99·7% (females) for pleural mesothelioma and 98·8% (males) and 100% (females) for bronchus and lung cancer. In Europe for the year 2000, asbestos-related occupational cancer rates ranged from 0·04 per 10(5) employees in Spain to 7·32 per 10(5) employees in Norway. These findings provide evidence of gross under-recognition of asbestos-related occupational cancers in Spain. Future work should investigate cases treated in the National Healthcare System to better establish the impact of asbestos on health in Spain.

  16. Plutonium research and related activities at the Amarillo National Resource Center for Plutonium

    International Nuclear Information System (INIS)

    Hartley, R.S.; Beard, C.A.; Barnes, D.L.

    1998-01-01

    With the end of the Cold War, the US and Russia are reducing their nuclear weapons stockpiles. What to do with the materials from thousands of excess nuclear weapons is an important international challenge. How to handle the remaining US stockpile to ensure safe storage and reliability, in light of the aging support infrastructure, is an important national challenge. To help address these challenges and related issues, the Amarillo National Resource Center for Plutonium is working on behalf of the State of Texas with the US Department of Energy (DOE). The center directs three major programs that address the key aspects of the plutonium management issue: (1) the Communications, Education, Training and Community Involvement Program, which focuses on informing the public about plutonium and providing technical education at all levels; (2) the Environmental, Safety, and Health (ES and H) Program, which investigates the key ES and H impacts of activities related to the DOE weapons complex in Texas; and (3) the Nuclear and Other Materials Program, which is aimed at minimizing safety and proliferation risks by helping to develop and advocate safe stewardship, storage, and disposition of nuclear weapons materials. This paper provides an overview of the center's nuclear activities described in four broad categories of international activities, materials safety, plutonium storage, and plutonium disposition

  17. Evaluating a national science and technology program using the human capital and relational asset perspectives.

    Science.gov (United States)

    Hung, Chia-Liang; Chou, Jerome Chih-Lung; Roan, Hung-Wei

    2010-11-01

    The purpose of this research is to evaluate the performance of the National Science and Technology Program (NSTP) by targeting the Taiwan National Telecommunication Program (NTP) initiated in 1998. The Taiwan telecommunications industry has prospered, currently occupying key positions in global markets even though NTP seldom contributes positively to patent citation performance. Hence, the authors of this study investigate the qualitative perspective of intellectual capital rather than quantitative technological indices. The current study focuses on both human capital and relational assets through surveys of 53 principal investigators of NTP projects and 63 industrial R&D managers of telecommunications corporations in the Taiwan market. Results show that NSTP member quality and the flow of employment are good indicators of human capital and that both perform better than the middle value in the case of Taiwan NTP. In addition, we find that industrial participants are more likely to share R&D resources than other academic researchers with higher intention of co-publishing, co-funding, and sharing equipment and facilities. The industrial NTP participants also have higher expectations regarding achieving advanced technology breakthroughs in contrast to non-NTP industrial interviewees. Moreover, industrial participants with greater industry-university cooperation intensity indeed obtain a particular advantage, that is, greater knowledge acquisition from other fields related to the effect of knowledge spillovers through the particular NSTP linkage. Accordingly, from the perspectives of human capital and relational assets, the authors conclude by articulating the importance of absorptive capacity resulting from good human capital and knowledge spillover contributed by relational assets within governmental technology policy and NSTP programming. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  18. Transient Relative Age Effects across annual age groups in National level Australian Swimming.

    Science.gov (United States)

    Cobley, Stephen; Abbott, Shaun; Dogramaci, Sera; Kable, Adam; Salter, James; Hintermann, Mirjam; Romann, Michael

    2017-12-29

    To determine the prevalence, magnitude and transient patterning of Relative Age Effects (RAEs) according to sex and stroke event across all age-groups at the Australian National age swimming Championships. Repeated years of cross-sectional participation data were examined. Participants were 6014 unique male (3185) and female (2829) swimmers (aged 12-18 years) who participated in Freestyle (50, 400m) and/or Breaststroke (100, 200m) at the National age swimming Championships between 2000-2014 (inclusive). RAE prevalence, magnitude and transience were determined using Chi-square tests and Cramer's V estimates for effect size. Odds Ratios (OR) and 95% Confidence Intervals (CI) examined relative age quartile discrepancies. These steps were applied across age-groups and according to sex and each stroke event. Consistent RAEs with large-medium effect sizes were evident for males at 12-15 years of age respectively, and with large-medium effects for females at 12-14 respectively across all four swimming strokes. RAE magnitude then consistently reduced with age across strokes (e.g., Q1 vs. Q4 OR range 16year old males=0.94-1.20; females=0.68-1.41). With few exceptions, by 15-16 years RAEs had typically dissipated; and by 17-18 years, descriptive and significant inverse RAEs emerged, reflecting overrepresentation of relatively younger swimmers. Performance advantages associated with relative age (and thereby likely growth and maturation) are transient. Greater consideration of transient performance and participation in athlete development systems is necessary. This may include revising the emphasis of sport programmes according to developmental stages and delaying forms of athlete selection to improve validity. Copyright © 2018 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  19. 75 FR 65647 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-10-26

    .... Paul Loether, National Register of Historic Places/National Historic Landmarks Program. AMERICAN SAMOA...., Maiden's Alley, Cherry Alley, Mulberry Alley, Bardstown, 10000905 Todd County Woodstock, 6338 Clarksville...

  20. New initiative links scientists and entertainers

    Science.gov (United States)

    Gwynne, Peter

    2009-01-01

    The US National Academy of Sciences has teamed up with Hollywood to improve the quality of science portrayed in films, TV shows and video games. The new Science and Entertainment Exchange (SEE) aims to create better links between entertainment-industry professionals and scientists to improve the credibility of programming related to science.

  1. The relative stabilities of cyclic dicationic derivatives of diphosphanes with three (3P) or four (4P) linked phosphorus atoms.

    Science.gov (United States)

    Bashforth, Rachel; Boyall, Alice J; Coffer, Philippa K; Dillon, Keith B; Goeta, Andrés E; Howard, Judith A K; Kenwright, Alan M; Probert, Michael R; Shepherd, Helena J; Thompson, Amber L

    2012-01-28

    Reaction of a diphosphane with a chlorophosphane in the presence of SnCl(2) or AlCl(3) leads to the formation of dicationic heterocycles with three (3P) or four (4P) linked phosphorus atoms. Some 3P derivatives with small alkyl substituents may also be prepared by direct alkylation of cyclic triphosphenium ions. Several new species were prepared in solution, some of which were isolated and characterised by single-crystal X-ray diffraction. Investigations into the factors favouring formation of 3P or 4P species are described.

  2. Sexual orientation, treatment utilization, and barriers for alcohol related problems: Findings from a nationally representative sample.

    Science.gov (United States)

    Allen, Junior Lloyd; Mowbray, Orion

    2016-04-01

    Gay, lesbian, and bisexual (GLB) individuals appear to have an increased likelihood of alcohol use disorders and treatment utilization for alcohol related problems compared to heterosexual individuals. Despite this increase, treatment utilization rates among GLB individuals remain low. In an effort to address this, our paper examined whether or not GLB individuals encounter unique barriers when pursuing treatment for alcohol related problems. Using data from the National Epidemiologic Survey on Alcohol Related Conditions (NESARC), we examined service sector specific factors, some of which included (a) utilization rates, (b) self-reported treatment barriers, and (c) whether or not there were emergent differences among GLB individuals, after controlling for socio-demographic and clinical characteristics. Findings indicated that GLB individuals reported higher severity rates for alcohol use disorders when compared to heterosexual individuals, and were significantly more likely to utilize treatment services for alcohol related problems, however, not across all treatment sectors. While similar patterns were observed when examining barriers to treatment, bisexual individuals reported significantly more barriers than heterosexual and gay/lesbian individuals. These findings underscored the importance of identifying and developing interventions that addresses treatment barriers associated with alcohol use service utilization among GLB populations, and creating improved outreach and education programs to better address stigmas associated with substance use and sexuality. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  3. Options for a National Framework for Benefit Distribution and Their Relation to Community-Based and National REDD+ Monitoring

    Directory of Open Access Journals (Sweden)

    Margaret Skutsch

    2014-07-01

    Full Text Available Monitoring is a central element in the implementation of national REDD+ and may be essential in providing the data needed to support benefit distribution. We discuss the options for benefit sharing systems in terms of technical feasibility and political acceptability in respect of equity considerations, and the kind of data that would be needed for the different options. We contrast output-based distribution systems, in which rewards are distributed according to performance measured in terms of carbon impacts, with input-based systems in which performance is measured in term of compliance with prescribed REDD+ activities. Output-based systems, which would require regular community carbon inventories to produce Tier 3 data locally, face various challenges particularly for the case of assessing avoided deforestation, and they may not be perceived as equitable. Input-based systems would require data on activities undertaken rather than change in stocks; this information could come from community-acquired data. We also consider how community monitored data could support national forest monitoring systems and the further development of national REDD+.

  4. Social outcomes associated with alcohol-related diagnoses: a population-based analysis using linked administrative data

    Directory of Open Access Journals (Sweden)

    Nathan Nickel

    2017-04-01

    Receiving an alcohol-related diagnosis is associated with subsequent increased use of social services and contacts with the justice system. Upstream efforts to reduce alcohol-related diagnoses may result in reduced use of social services and justice contacts.

  5. National nostalgia : A group-based emotion that benefits the in-group but hampers intergroup relations

    NARCIS (Netherlands)

    Smeekes, A.N.

    2015-01-01

    Social psychological research on nostalgia has mainly considered this emotion at the individual level rather than the group level. The current paper proposes that group-based nostalgia for the nation (i.e., national nostalgia) is likely to be related to a positive in-group orientation and a negative

  6. 76 FR 22665 - Release of Final Document Related to the Review of the National Ambient Air Quality Standards for...

    Science.gov (United States)

    2011-04-22

    ... criteria. The revised air quality criteria reflect advances in scientific knowledge on the effects of the... National Ambient Air Quality Standards, contains staff analyses of the scientific bases for alternative... Document Related to the Review of the National Ambient Air Quality Standards for Particulate Matter AGENCY...

  7. A qualitative study exploring the experiences and emotional responses of female community continence link workers and female patients in relation to performing clean intermittent self-catheterisation

    OpenAIRE

    Ramm, Dianne; Kane, Ros

    2011-01-01

    Aim: This paper represents a report of a study designed to explore the experiences of female community continence link nurses in relation to female catheterisation and their psychological and educational preparedness to teach it. The lived experiences and emotional responses of female patients learning to perform Clean Intermittent Self-Catheterisation (CISC) are also examined. Background: There is general consensus that CISC should be considered in preference to indwelling catheterisat...

  8. Activities of the National Academy of Sciences in relation to the Radiation Effects Research Foundation

    International Nuclear Information System (INIS)

    Edington, C.W.

    1991-02-01

    The activities of the National Academy of Sciences (NAS), in relation to the Radiation Effects Research Foundation (RERF), has a long history and the specific time period supported by this contract is but a small piece of the long-term continuing program. As a background, in August 1945, atomic bombs were dropped on Hiroshima (6 August) and Nagasaki (9 August). Shortly after the bombings, US medical teams joined forces with their Japanese counterparts to form a Joint Commission for the Investigation of the Effects of the Atomic Bombs. As a result of the Joint Commission's investigations, it was determined that consideration should be given to the establishment of a long-term study of the potential late health effects of exposure of the survivors to radiation from the bombs. The results obtained from RERF studies contribute the vast majority of information that provides a better understanding of radiation effects on humans. This information has been used extensively by national organizations and international committees for estimating risks associated with radiation exposures. The estimated risks developed by these independent organizations are used by government agencies around the world to establish standards for protection of individuals exposed in the occupational, medical, and general environment. Some of these results are described briefly in this report

  9. Lay Definitions of Happiness across Nations: The Primacy of Inner Harmony and Relational Connectedness.

    Science.gov (United States)

    Delle Fave, Antonella; Brdar, Ingrid; Wissing, Marié P; Araujo, Ulisses; Castro Solano, Alejandro; Freire, Teresa; Hernández-Pozo, María Del Rocío; Jose, Paul; Martos, Tamás; Nafstad, Hilde E; Nakamura, Jeanne; Singh, Kamlesh; Soosai-Nathan, Lawrence

    2016-01-01

    In well-being research the term happiness is often used as synonymous with life satisfaction. However, little is known about lay people's understanding of happiness. Building on the available literature, this study explored lay definitions of happiness across nations and cultural dimensions, analyzing their components and relationship with participants' demographic features. Participants were 2799 adults (age range = 30-60, 50% women) living in urban areas of Argentina, Brazil, Croatia, Hungary, India, Italy, Mexico, New Zealand, Norway, Portugal, South Africa, and United States. They completed the Eudaimonic and Hedonic Happiness Investigation (EHHI), reporting, among other information, their own definition of happiness. Answers comprised definitions referring to a broad range of life domains, covering both the contextual-social sphere and the psychological sphere. Across countries and with little variation by age and gender, inner harmony predominated among psychological definitions, and family and social relationships among contextual definitions. Whereas relationships are widely acknowledged as basic happiness components, inner harmony is substantially neglected. Nevertheless, its cross-national primacy, together with relations, is consistent with the view of an ontological interconnectedness characterizing living systems, shared by several conceptual frameworks across disciplines and cultures. At the methodological level, these findings suggest the potential of a bottom-up, mixed method approach to contextualize psychological dimensions within culture and lay understanding.

  10. Lay Definitions of Happiness across Nations: The Primacy of Inner Harmony and Relational Connectedness

    Science.gov (United States)

    Delle Fave, Antonella; Brdar, Ingrid; Wissing, Marié P.; Araujo, Ulisses; Castro Solano, Alejandro; Freire, Teresa; Hernández-Pozo, María Del Rocío; Jose, Paul; Martos, Tamás; Nafstad, Hilde E.; Nakamura, Jeanne; Singh, Kamlesh; Soosai-Nathan, Lawrence

    2016-01-01

    In well-being research the term happiness is often used as synonymous with life satisfaction. However, little is known about lay people's understanding of happiness. Building on the available literature, this study explored lay definitions of happiness across nations and cultural dimensions, analyzing their components and relationship with participants' demographic features. Participants were 2799 adults (age range = 30–60, 50% women) living in urban areas of Argentina, Brazil, Croatia, Hungary, India, Italy, Mexico, New Zealand, Norway, Portugal, South Africa, and United States. They completed the Eudaimonic and Hedonic Happiness Investigation (EHHI), reporting, among other information, their own definition of happiness. Answers comprised definitions referring to a broad range of life domains, covering both the contextual-social sphere and the psychological sphere. Across countries and with little variation by age and gender, inner harmony predominated among psychological definitions, and family and social relationships among contextual definitions. Whereas relationships are widely acknowledged as basic happiness components, inner harmony is substantially neglected. Nevertheless, its cross-national primacy, together with relations, is consistent with the view of an ontological interconnectedness characterizing living systems, shared by several conceptual frameworks across disciplines and cultures. At the methodological level, these findings suggest the potential of a bottom-up, mixed method approach to contextualize psychological dimensions within culture and lay understanding. PMID:26858677

  11. Assessment of COPD-related outcomes via a national electronic medical record database.

    Science.gov (United States)

    Asche, Carl; Said, Quayyim; Joish, Vijay; Hall, Charles Oaxaca; Brixner, Diana

    2008-01-01

    The technology and sophistication of healthcare utilization databases have expanded over the last decade to include results of lab tests, vital signs, and other clinical information. This review provides an assessment of the methodological and analytical challenges of conducting chronic obstructive pulmonary disease (COPD) outcomes research in a national electronic medical records (EMR) dataset and its potential application towards the assessment of national health policy issues, as well as a description of the challenges or limitations. An EMR database and its application to measuring outcomes for COPD are described. The ability to measure adherence to the COPD evidence-based practice guidelines, generated by the NIH and HEDIS quality indicators, in this database was examined. Case studies, before and after their publication, were used to assess the adherence to guidelines and gauge the conformity to quality indicators. EMR was the only source of information for pulmonary function tests, but low frequency in ordering by primary care was an issue. The EMR data can be used to explore impact of variation in healthcare provision on clinical outcomes. The EMR database permits access to specific lab data and biometric information. The richness and depth of information on "real world" use of health services for large population-based analytical studies at relatively low cost render such databases an attractive resource for outcomes research. Various sources of information exist to perform outcomes research. It is important to understand the desired endpoints of such research and choose the appropriate database source.

  12. Understanding drug-related mortality in released prisoners: a review of national coronial records

    Directory of Open Access Journals (Sweden)

    Andrews Jessica Y

    2012-04-01

    Full Text Available Abstract Background The prisoner population is characterised by a high burden of disease and social disadvantage, and ex-prisoners are at increased risk of death following release. Much of the excess mortality can be attributed to an increased risk of unnatural death, particularly from drug overdose; however, relatively few studies have investigated the circumstances surrounding drug-related deaths among released prisoners. This study aimed to explore and compare the circumstances of death for those who died from accidental drug-related causes to those who died from all other reportable causes. Methods A nationwide search of the Australian National Coroners Information System (NCIS was conducted to identify reportable deaths among ex-prisoners from 2000 to 2007. Using a structured coding form, NCIS records for these cases were interrogated to explore causes and circumstances of death. Results Coronial records for 388 deceased ex-prisoners were identified. Almost half of these deaths were a result of accidental drug-related causes (45%. The majority of accidental drug-related deaths occurred in a home environment, and poly-substance use at or around the time of death was common, recorded in 72% of drug-related deaths. Ex-prisoners who died of accidental drug-related causes were on average younger and less likely to be Indigenous, born in Australia, married, or living alone at or around the time of death, compared with those who died from all other reportable causes. Evidence of mental illness or self-harm was less common among accidental drug-related deaths, whereas evidence of previous drug overdose, injecting drug use, history of heroin use and history of drug withdrawal in the previous six months were more common. Conclusions Drug-related deaths are common among ex-prisoners and often occur in a home (vs. public setting. They are often associated with use of multiple substances at or around the time of death, risky drug-use patterns, and even

  13. National action plan 2016-2019 for the management of the radon-related risk

    International Nuclear Information System (INIS)

    Mortureux, Marc; Vallet, Benoit; Struillou, Yves; Girometti, Laurent

    2017-01-01

    After a brief presentation of the context, and a presentation of aspects related to the plan governance and strategies (plan steering, actors in the radon risk management, synthesis of main actions in France, regulatory evolutions and new strategies), this report presents the three axes of the national action plan for 2016-2019. The first one consists in the implementation of a global strategy of information and in developing tools to collect and share information. The second one consists in a continuous knowledge improvement. The third one consists in a better taking into account of radon risk management in buildings. Sheets are then proposed which describe the various actions associated with these axes (5 actions for the first one, 10 for the second, and 5 for the third one). Each sheet comprises the action title, its objectives, methods and tools, its coordinator and actors, its agenda and current status

  14. The mental health impact of AIDS-related mortality in South Africa: a national study

    Science.gov (United States)

    Myer, L; Seedat, S; Stein, D J; Moomal, H; Williams, D R

    2011-01-01

    Background Few data exist on how the HIV/AIDS epidemic may influence population mental health. The associations were examined between knowing someone who died of HIV/AIDS and common mental disorders among South African adults. Methods Between 2002 and 2004, a nationally representative sample of 4351 adults were interviewed about personally knowing someone who died of HIV/AIDS, and the World Health Organization Composite International Diagnostic Interview was used to generate psychiatric diagnoses for depression, anxiety and substance abuse disorders during the preceding 12 months based on the Diagnostic and Statistical Manual, 4th edition (DSM-IV). Results Overall, 42.2% of the sample knew someone who died of HIV/AIDS, and 16.5% met the criteria for at least one DSM-IV diagnosis. Individuals who knew someone who died of HIV/AIDS were significantly more likely to have any DSM-IV defined disorder, including any depressive, anxiety or substance-related disorder (pdrug dependence or abuse. Based on these results, it is estimated that up to 15% of 12-month DSM-IV disorders in the South African adult population may be related to knowing someone who died of HIV/AIDS. Conclusion These novel data suggest that AIDS-related mortality may contribute substantially to the burden of mental disorders in settings of high HIV prevalence. While this finding requires further investigation, these data suggest the need to strengthen mental health services in communities where HIV/AIDS is prevalent. PMID:19074926

  15. Oral health related behaviors among adult Tanzanians: a national pathfinder survey

    Directory of Open Access Journals (Sweden)

    Senkoro Ahadieli R

    2009-09-01

    Full Text Available Abstract Background The oral health education programs which have been organised and delivered in Tanzania were not based on a thorough understanding of behaviours which influence oral health. Therefore, evaluation of these programs became difficult. This study aimed at investigating the oral health related behaviours and their determinants among Tanzanian adults. Methods A national pathfinder cross sectional survey was conducted in 2006 involving 1759 respondents from the six geographic zones of mainland Tanzania. Frequency distributions, Chi square and multiple logistic regression analyses were performed using SPSS version 13.0. Results The rates of abstinence from alcohol for the past 30 days and life time smoking were 61.6% and 16.7% respectively, with males being more likely to smoke (OR 9.2, CI 6.3 -12.9, p Conclusion The findings of this study demonstrated social demographic disparities in relation to oral health related behaviors, while dental pain was associated with low consumption of sugar and high likelihood to take alcohol.

  16. Change in the structures, dynamics and disease-related mortality rates of the population of Qatari nationals: 2007–2011

    Directory of Open Access Journals (Sweden)

    Mohamed H. Al-Thani

    2014-12-01

    Conclusion: Public health strategies, approaches and programs developed to reduce disease burden and the related death, should be tailored to target the population of Qatari nationals which exhibits characteristics that vary from the entire Qatari population.

  17. Relating follicly-challenged compact stars to bald black holes: A link between two no-hair properties

    Science.gov (United States)

    Yagi, Kent; Yunes, Nicolás

    2015-05-01

    Compact stars satisfy certain no-hair relations through which their multipole moments are given by their mass, spin and quadrupole moment. These relations are approximately independent of their equation of state, relating pressure to density. Such relations are similar to the black hole no-hair theorems, but these possess event horizons inside which information that led to their formation can hide. Compact stars do not possess horizons, so whether their no-hair relations are related to the black hole ones is unclear. We investigate how the two relations are related by studying relations among multipole moments for compact stars with anisotropic pressure as a toy model, which allows such stars to be more compact than those with isotropic pressure. We here show numerically that the compact star no-hair relations approach the black hole ones as the compactness approaches that of a black hole. We also prove analytically that the current dipole moment exactly reaches the black hole limit quadratically in compactness as strongly anisotropic stars approach the black hole limit. We moreover show that compact stars become progressively oblate in this limit, even if prolate at low compactness due to strong anisotropies.

  18. Body weight concerns: Cross-national study and identification of factors related to eating disorders

    Science.gov (United States)

    da Silva, Wanderson Roberto; Santana, Moema de Souza; Maroco, João; Maloa, Benvindo Felismino Samuel

    2017-01-01

    Background Body weight concerns are common among individuals with eating disorders, and this construct can be assessed using psychometric instruments. The Weight Concerns Scale (WCS) is commonly used to assess body weight concerns. Aims To evaluate the psychometric properties of the WCS with Brazilian, Portuguese, and Mozambican female college students; to estimate body weight concerns; and to identify factors related to eating disorders. Methods Confirmatory factor analysis was performed. Factorial, convergent, concurrent, and divergent validity, as well as reliability, were assessed. Cross-national invariance was tested by means of multigroup analysis. Structural models were tested using the WCS as the dependent variable, while demographic and academic variables and body mass index were used as independent variables. Logistic models were tested to estimate the likelihood of eating disorders being developed in specific groups. Results Participants were 2,068 female students. The psychometric properties of the WCS were adequate for the Portuguese sample; however, for the Brazilian and Mozambican samples, it was necessary to correlate the errors of two items to improve model fit. The WCS did not show cross-national invariance. The variables “thoughts about dropping out of college,” “medication use because of studies,” “medication and supplements use for body change,” “body mass index,” “socioeconomic status,” “age,” and “performance in course” were significant predictors of body weight concerns. Overall, 24.4% (95% confidence interval = 22.9–26.7) of the students were likely to develop eating disorders. Students under 21 years old, who use medication and supplements for body change, and who were classified as overweight/obese have increased likelihood of developing eating disorders. Conclusion The WCS showed good psychometric properties with Brazilian, Portuguese, and Mozambican students; however, it did not show cross-national

  19. Bullying perpetration and victimization as externalizing and internalizing pathways: A retrospective study linking parenting styles and self-esteem to depression, alcohol use, and alcohol-related problems

    Science.gov (United States)

    Patock-Peckham, Julie A; Medina, Mia; Terrell, Nathan; Belton, Daniel; King, Kevin M

    2016-01-01

    Emerging research suggests significant positive associations between bullying and substance use behaviors. However, these studies typically focused either on the link between substance use and bullying perpetration or victimization, and few have conceptualized bullying perpetration and/or victimization as mediators. In this study, we simultaneously tested past bullying perpetration and victimization as mediational pathways from retrospective report of parenting styles and global self-esteem to current depressive symptoms, alcohol use and alcohol-related problems. Data were collected from a college sample of 419 drinkers. Mediation effects were conducted using a bias-corrected bootstrap technique in structural equation modeling. Two-path mediation analyses indicated that mother and father authoritativeness were protective against bully victimization and depression through higher self-esteem. Conversely, having a permissive or authoritarian mother was positively linked to bullying perpetration, which in turn was associated with increased alcohol use, and to a lesser degree, more alcohol-related problems. Mother authoritarianism was associated with alcohol-related problems through depressive symptoms. Three-path mediation analyses suggested a trend in which individuals with higher self-esteem were less likely to report alcohol-related problems through lower levels of bullying victimization and depression. Results suggested that bullying perpetration and victimization may respectively serve as externalizing and internalizing pathways through which parenting styles and self-esteem are linked to depression and alcohol-related outcomes. The present study identified multiple modifiable precursors of, and mediational pathways to, alcohol-related problems which could guide the development and implementation of prevention programs targeting problematic alcohol use. PMID:26757486

  20. Bullying Perpetration and Victimization as Externalizing and Internalizing Pathways: A Retrospective Study Linking Parenting Styles and Self-Esteem to Depression, Alcohol Use, and Alcohol-Related Problems.

    Science.gov (United States)

    Luk, Jeremy W; Patock-Peckham, Julie A; Medina, Mia; Terrell, Nathan; Belton, Daniel; King, Kevin M

    2016-01-02

    Emerging research suggests significant positive associations between bullying and substance use behaviors. However, these studies typically focused either on the link between substance use and bullying perpetration or victimization, and few have conceptualized bullying perpetration and/or victimization as mediators. In this study, we simultaneously tested past bullying perpetration and victimization as mediational pathways from retrospective report of parenting styles and global self-esteem to current depressive symptoms, alcohol use, and alcohol-related problems. Data were collected from a college sample of 419 drinkers. Mediation effects were conducted using a bias-corrected bootstrap technique within a structural equation modeling framework. Two-path mediation analyses indicated that mother and father authoritativeness were protective against bully victimization and depression through higher self-esteem. Conversely, having a permissive or authoritarian mother was positively linked to bullying perpetration, which in turn, was associated with increased alcohol use, and to a lesser degree, more alcohol-related problems. Mother authoritarianism was associated with alcohol-related problems through depressive symptoms. Three-path mediation analyses suggested a trend in which individuals with higher self-esteem were less likely to report alcohol-related problems through lower levels of bullying victimization and depression. Results suggested that bullying perpetration and victimization may, respectively, serve as externalizing and internalizing pathways through which parenting styles and self-esteem are linked to depression and alcohol-related outcomes. The present study identified multiple modifiable precursors of, and mediational pathways to, alcohol-related problems which could guide the development and implementation of prevention programs targeting problematic alcohol use.

  1. AIDS-related primary central nervous system lymphoma: a Norwegian national survey 1989–2003

    International Nuclear Information System (INIS)

    Haldorsen, Ingfrid S; Kråkenes, Jostein; Goplen, Anne K; Dunlop, Oona; Mella, Olav; Espeland, Ansgar

    2008-01-01

    Primary central nervous system lymphoma (PCNSL) is a frequent complication in acquired immunodeficiency syndrome (AIDS). The objective of this survey was to investigate incidence, clinical features, radiological findings, histologic diagnosis, treatment and outcome for all patients with histologically verified AIDS-related PCNSL diagnosed in Norway in 1989–2003. We identified the patients by chart review of all cases recorded as PCNSL in The Norwegian Cancer Registry (by law recording all cases of cancer in Norway) and all cases recorded as AIDS-related PCNSL in the autopsy registry at a hospital having 67% autopsy rate and treating 59% of AIDS patients in Norway, from 1989 to 2003. Histologic material and radiological images were reviewed. We used person-time techniques to calculate incidence rates of PCNSL among AIDS patients based on recordings on AIDS at the Norwegian Surveillance System for Communicable Diseases (by law recording all cases of AIDS in Norway). Twenty-nine patients had histologically confirmed, newly diagnosed AIDS-related PCNSL in Norway from 1989–2003. Only 2 patients had this diagnosis established while alive. AIDS patients had 5.5% lifetime risk of PCNSL. Their absolute incidence rate of PCNSL per 100 person-years was 1.7 (95%CI: 1.1–2.4) and decreased during the consecutive 5-year periods from 3.6, to 2.5, and to 0.4 (p < 0.001). Median survival from initial symptom of PCNSL was 2.3 months, but one patient was still alive 4 years after completed radiotherapy. This is the first national survey to confirm decreasing incidence of AIDS-related PCNSL. Despite dismal survival in most patients, the possibility of long term survival should prompt more aggressive diagnostics in suspected PCNSL

  2. Prevalence and nature of cardiovascular disease in methamphetamine-related death: A national study.

    Science.gov (United States)

    Darke, Shane; Duflou, Johan; Kaye, Sharlene

    2017-10-01

    Methamphetamine dependence is a major public health problem. This study examined the nature, and extent, of cardiovascular disease amongst cases of methamphetamine-related death in Australia, 2009-2015. Analysis of 894 cases of methamphetamine-related death with full autopsy reports retrieved from the National Coronial Information System. The mean age was 37.9yrs (range 15-69yrs) and 78.5% were male. A quarter (26.3%) of cases had enlarged hearts and left ventricular hypertrophy was diagnosed in 18.9%. Severe coronary artery disease was present in 19.0%, the left coronary artery being the vessel most frequently stenosed (16.6%). Replacement fibrosis (evidence of earlier ischaemic events) in the heart muscle was observed in 19.8% of cases, and cardiomyopathy was diagnosed in 5.5%. Histological evidence of hypertension was observed in 32.7% of cases. With the exception of cardiomyopathy, equally common amongst both sexes, cardiovascular disease was more common amongst males, and those aged >35yrs. Clinically significant levels of cardiovascular disease were also observed amongst cases where the cause of death was not attributed to cardiovascular disease: cardiomegaly (19.3%), left ventricular hypertrophy (14.6%), severe coronary artery disease (9.4%), replacement fibrosis (14.4%), cardiomyopathy (3.3%). Cardiovascular disease was highly prevalent, despite the relatively young age of cases. With methamphetamine use increasing rapidly in major regions, cardiovascular disease and cardiovascular-related death will likely increase amongst methamphetamine users. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. The Role of Preschool Relational and Physical Aggression in the Transition to Kindergarten: Links with Social-Psychological Adjustment

    Science.gov (United States)

    Gower, Amy L.; Lingras, Katherine A.; Mathieson, Lindsay C.; Kawabata, Yoshito; Crick, Nicki R.

    2014-01-01

    Research Findings: The transition to kindergarten has important ramifications for future achievement and psychosocial outcomes. Research suggests that physical aggression may be related to difficulty during school transitions, yet no studies to date have examined the role of relational aggression in these transitions. This article examines how…

  4. 76 FR 46839 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-08-03

    ... to do so. J. Paul Loether, Chief, National Register of Historic Places/National Historic Landmarks..., 7632 US 20, Cherry Valley, 11000543 NORTH CAROLINA Ashe County Lansing Historic District, Roughly...

  5. 78 FR 24232 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-04-24

    ..., National Register of Historic Places/National Historic Landmarks Program. GEORGIA Coffee County 63rd Army... Market, 6115 Maple St., Omaha, 13000276 TEXAS Wood County Carlock, Marcus DeWitt, House, 407 S. Main St...

  6. Linking data to tobacco control program action among students aged 13-15 in Association of Southeast Asian Nations (ASEAN) member states, 2000-2006.

    Science.gov (United States)

    Sirichotiratana, N; Sovann, S; Aditama, T Y; Krishnan, M; Kyaing, N N; Miguel-Baquilod, M; Hai, P T; Sinha, D N; Warren, C W; Jones, N R

    2008-12-01

    The Association of Southeast Asian Nations (ASEAN) has made tobacco use prevention a primary health issue. All ASEAN countries except Indonesia have ratified the World Health Organization Framework Convention on Tobacco Control (WHO FCTC), the world's first public health treaty on tobacco control. Global Youth Tobacco Survey (GYTS) data were collected from representative samples of students in school grades associated with ages 13-15 in Cambodia, Indonesia, Laos (Vientiane), Malaysia, Myanmar, Philippines, Singapore, Thailand and Vietnam (Hanoi). Current cigarette smoking ranged from less than 5% (Vietnam and Cambodia) to 20.2% in Malaysia. Current use of tobacco products other than cigarettes was less than 10% in all countries. Boys were significantly more likely than girls to smoke cigarettes or use other tobacco products. Exposure to second-hand smoke in public places was greater than 50%, direct pro-tobacco advertising exposure was greater than 75% and over 10% of students were exposed to indirect advertising. Over 60% of students who currently smoked cigarettes wanted to stop, but 80% who tried to quit in the year prior to the survey failed. Efforts to reduce the current and projected harm caused by tobacco use in the ASEAN countries are urgently needed. ASEAN countries need to expand their national comprehensive tobacco prevention and control programs and enforce those laws already passed. Without this effort little reduction can be expected in the burden of chronic diseases and tobacco-related mortality.

  7. Inherent X-Linked Genetic Variability and Cellular Mosaicism Unique to Females Contribute to Sex-Related Differences in the Innate Immune Response

    Directory of Open Access Journals (Sweden)

    Zoltan Spolarics

    2017-11-01

    Full Text Available Females have a longer lifespan and better general health than males. Considerable number of studies also demonstrated that, after trauma and sepsis, females present better outcomes as compared to males indicating sex-related differences in the innate immune response. The current notion is that differences in the immuno-modulatory effects of sex hormones are the underlying causative mechanism. However, the field remains controversial and the exclusive role of sex hormones has been challenged. Here, we propose that polymorphic X-linked immune competent genes, which are abundant in the population are important players in sex-based immuno-modulation and play a key role in causing sex-related outcome differences following trauma or sepsis. We describe the differences in X chromosome (ChrX regulation between males and females and its consequences in the context of common X-linked polymorphisms at the individual as well as population level. We also discuss the potential pathophysiological and immune-modulatory aspects of ChrX cellular mosaicism, which is unique to females and how this may contribute to sex-biased immune-modulation. The potential confounding effects of ChrX skewing of cell progenitors at the bone marrow is also presented together with aspects of acute trauma-induced de novo ChrX skewing at the periphery. In support of the hypothesis, novel observations indicating ChrX skewing in a female trauma cohort as well as case studies depicting the temporal relationship between trauma-induced cellular skewing and the clinical course are also described. Finally, we list and discuss a selected set of polymorphic X-linked genes, which are frequent in the population and have key regulatory or metabolic functions in the innate immune response and, therefore, are primary candidates for mediating sex-biased immune responses. We conclude that sex-related differences in a variety of disease processes including the innate inflammatory response to injury

  8. PERIPHERAL IMMUNE SYSTEM SUPPRESSION IN EARLY ABSTINENT ALCOHOL DEPENDENT INDIVIDUALS: LINKS TO STRESS AND CUE-RELATED CRAVING

    Science.gov (United States)

    Fox, Helen C; Milivojevic, Verica; Angarita, Gustavo A; Stowe, Raymond; Sinha, Rajita

    2017-01-01

    Background Peripheral immune system cytokines may play an integral role in underlying sensitized stress response and alcohol craving during early withdrawal. To date, the nature of these immune changes during early abstinence have not been examined. Methods Thirty-nine early abstinent, treatment-seeking alcohol dependent individuals and 46 socially drinking controls were exposed to three guided imageries: stress, alcohol cue and neutral. These were presented randomly across consecutive days. Plasma measures of tumor necrosis factor alpha (TNFα), tumor necrosis factor receptor 1 (TNFR1), interleukin-6 (IL-6), and interleukin-10 (IL-10), were collected at baseline, immediately after imagery and at various recovery time-points. Ratings of alcohol craving, negative mood and anxiety were also obtained at the same time-points. Results The alcohol group demonstrated decreased basal IL-10 compared with controls particularly following exposure to alcohol cue. They also showed a dampened TNFα and TNFR1 response to stress and cue, respectively, and a generalized suppression of IL-6. In the alcohol group, these immune system adaptations occurred alongside significant elevations in anxiety, negative mood and alcohol craving. Conclusions Findings demonstrate that broad immuno-suppression is still observed in alcohol dependent individuals after three weeks of abstinence and may be linked to motivation for alcohol. PMID:28675117

  9. A link between double-strand break-related repair and V(D)J recombination: the scid mutation

    International Nuclear Information System (INIS)

    Hendrickson, E.A.; Qin, X.Q.; Bump, E.A.; Schatz, D.G.; Oettinger, M.; Weaver, D.T.

    1991-01-01

    We show here that mammalian site-specific recombination and DNA-repair pathways share a common factor. The effects of DNA-damaging agents on cell lines derived from mice homozygous for the scid (severe combined immune deficiency) mutation were studied. Surprisingly, all scid cell lines exhibited a profound hypersensitivity to DNA-damaging agents that caused double-strand breaks (x-irradiation and bleomycin) but not to other chemicals that caused single-strand breaks or cross-links. Neutral filter elution assays demonstrated that the x-irradiation hypersensitivity could be correlated with a deficiency in repairing double-strand breaks. These data suggest that the scid gene product is involved in two pathways: DNA repair of random double-strand breaks and the site-specific and lymphoid-restricted variable-(diversity)-joining [V(D)J] DNA rearrangement process. We propose that the scid gene product performs a similar function in both pathways and may be a ubiquitous protein

  10. Can the dopaminergic-related effects of general anesthetics be linked to mechanisms involved in drug abuse and addiction?

    Science.gov (United States)

    Melo, A; Tavares, I; Sousa, N; Pêgo, J M

    2015-08-01

    General anesthetics (GA) are well known for the ability to induce a state of reversible loss of consciousness and unresponsiveness to painful stimuli. However, evidence from animal models and clinical studies show that GA exposure may induce behavioral changes beyond acute effects. Most research and concerns are focused on changes in cognition and memory. We will look at effects of GA on behavior that is mediated by the dopaminergic system. Pharmacological resemblance of GA with drugs of abuse, and the complexity and importance of dopaminergic systems in both reward seeking and addictive illnesses make us believe that it deserves an overview about what is already known and what matters to us as healthcare workers and specifically as anesthesiologists. A review of available evidence strongly suggests that there may be a link between the effects of GA on the brain and substance abuse, partly explained by their influence on the dopaminergic system. © 2015 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  11. Injuries to children in the United States related to trampolines, 1990-1995: a national epidemic.

    Science.gov (United States)

    Smith, G A

    1998-03-01

    To describe the epidemiology of trampoline-related injuries among children in the United States. A retrospective analysis of data for children 18 years old and younger from the National Electronic Injury Surveillance System of the United States Consumer Product Safety Commission for 1990 through 1995. There were an estimated 249 400 trampoline-related injuries [95% confidence interval (CI), 166 300-332 500] to children 18 years old and younger treated in hospital emergency departments in the United States during the 6-year study period. The number of injuries increased by 98% from 29 600 in 1990 to 58 400 in 1995, with an average of 41 600 (95% CI, 27 700-55 500) injuries per year, or 59.4 injuries per 100 000 United States children per year (95% CI, 39.6-79.3). The median age of injured children was 10 years, and 50% were males. Ninety-three percent of injuries occurred at home. Injuries to the extremities predominated among children of all ages and accounted for more than 70% of all injuries. This study identified several age-specific injury patterns. There was an inverse relationship between age versus the relative frequency of upper extremity injuries, and fractures and dislocations; and there was a direct relationship between age versus lower extremity injuries and soft tissue injury. There was also an inverse relationship between age versus facial injuries, head and neck injuries, and lacerations. Annually, an estimated 1400 children (95% CI, 800-2000), or 2.0 per 100 000 United States children (95% CI, 1. 1-2.9), required hospital admission or interhospital transfer because of a trampoline-related injury. This represented 3.3% of all children with a trampoline-associated injury. Fractures or dislocations accounted for 83% of injuries among admitted or transferred children, and children with a fracture or dislocation were more likely to be admitted or transferred to another hospital (8.4%) than children with other types of injury (relative risk, 10.80; 95% CI

  12. Determinants in Adolescence of Stroke-Related Hospital Stay Duration in Men: A National Cohort Study.

    Science.gov (United States)

    Bergh, Cecilia; Udumyan, Ruzan; Appelros, Peter; Fall, Katja; Montgomery, Scott

    2016-09-01

    Physical and psychological characteristics in adolescence are associated with subsequent stroke risk. Our aim is to investigate their relevance to length of hospital stay and risk of second stroke. Swedish men born between 1952 and 1956 (n=237 879) were followed from 1987 to 2010 using information from population-based national registers. Stress resilience, body mass index, cognitive function, physical fitness, and blood pressure were measured at compulsory military conscription examinations in late adolescence. Joint Cox proportional hazards models estimated the associations of these characteristics with long compared with short duration of stroke-related hospital stay and with second stroke compared with first. Some 3000 men were diagnosed with nonfatal stroke between ages 31 and 58 years. Low stress resilience, underweight, and higher systolic blood pressure (per 1-mm Hg increase) during adolescence were associated with longer hospital stay (compared with shorter) in ischemic stroke, with adjusted relative hazard ratios (and 95% confidence intervals) of 1.46 (1.08-1.89), 1.41 (1.04-1.91), and 1.01 (1.00-1.02), respectively. Elevated systolic and diastolic blood pressures during adolescence were associated with longer hospital stay in men with intracerebral hemorrhage: 1.01 (1.00-1.03) and 1.02 (1.00-1.04), respectively. Among both stroke types, obesity in adolescence conferred an increased risk of second stroke: 2.06 (1.21-3.45). Some characteristics relevant to length of stroke-related hospital stay and risk of second stroke are already present in adolescence. Early lifestyle influences are of importance not only to stroke risk by middle age but also to recurrence and use of healthcare resources among stroke survivors. © 2016 American Heart Association, Inc.

  13. Socio-Economic Factors Related to Moral Reasoning in Childhood and Adolescence: The Missing Link between Brain and Behavior

    Directory of Open Access Journals (Sweden)

    Simona Carla Silvia eCaravita

    2012-09-01

    Full Text Available Neuroscientific and psychological research on moral development has until now developed independently, referring to distinct theoretical models, contents and methods. In particular, the influence of socio-economic and cultural factors on morality has been broadly investigated by psychologists but as yet has not been investigated by neuroscientists. The value of bridging these two areas both theoretically and methodologically has, however, been suggested. This study aims at providing a first connection between neuroscientific and psychological literature on morality by investigating whether socio-economic dimensions, i.e. living socio-geographic/economic area, immigrant status and SES, affect moral reasoning as operationalized in moral domain theory (a seminal approach in psychological studies on morality and in Greene and colleagues’ (2001 perspective (one of the main approaches in neuroethics research. Participants were 81 primary school (M = 8.98 yrs.; SD = 0.39, 72 middle school (M = 12.14 yrs.; SD = 0.61 and 73 high school (M = 15.10 yrs.; SD = 0.38 students from rural and urban areas. Participants’ immigrant status (native vs. immigrant and family SES level were recorded. Moral reasoning was assessed by means of a series of personal and impersonal dilemmas based on Greene and colleagues' (2001 neuroimaging experiment and a series of moral and socio-conventional rule dilemmas based on the moral domain theory. Living socio-geographic/economic area, immigrant status and SES mainly affected evaluations of moral and, to a higher extent, socio-conventional dilemmas, but had no impact on judgment of personal and impersonal dilemmas. Results are mainly discussed from the angle of possible theoretical links and suggestions emerging for studies on moral reasoning in the frameworks of neuroscience and psychology.

  14. Mediational links among parenting styles, perceptions of parental confidence, self-esteem, and depression on alcohol-related problems in emerging adulthood.

    Science.gov (United States)

    Patock-Peckham, Julie A; Morgan-Lopez, Antonio A

    2009-03-01

    Depression is often found to be comorbid with alcohol-related problems. Parental overprotection, which may be of particular importance during emerging adulthood, has been linked to internalizing symptoms in offspring. This article evaluates the impact of parenting styles and parental confidence in their offspring on an internalizing pathway to alcohol-related problems through self-esteem and depression. Mediational links were tested among parenting styles (authoritative, authoritarian, permissive), parental confidence (overprotection, autonomy), self-esteem, depression, and alcohol-related problems. A two-group, multiple indicator multiple-cause structural equation model with 441 (216 female, 225 male) college students was examined. Overall, having a father who was confident in his child's ability to make autonomous decisions was protective against depression for both genders. Perceptions of paternal autonomy mediated the impact of the fathers' parenting styles (authoritative, permissive) on depression for both genders. For men, parental overprotection mediated the impact of an authoritarian father on self-esteem, and self-esteem mediated the impact of parental overprotection on depression. Moreover, among men, perceptions of maternal autonomy mediated the impact of the mothers' parenting styles (authoritative, permissive) on self-esteem, and self-esteem mediated the impact of maternal autonomy on depression. The current pattern of findings is distinct from pathways through behavioral undercontrol with influences from the same-sex parent for both genders. These findings indicate that parenting may have differential influences on internalizing pathways to alcohol-related problems.

  15. Mediational Links Among Parenting Styles, Perceptions of Parental Confidence, Self-Esteem, and Depression on Alcohol-Related Problems in Emerging Adulthood*

    Science.gov (United States)

    Patock-Peckham, Julie A.; Morgan-Lopez, Antonio A.

    2009-01-01

    Objective: Depression is often found to be comorbid with alcohol-related problems. Parental overprotection, which may be of particular importance during emerging adulthood, has been linked to internalizing symptoms in offspring. This article evaluates the impact of parenting styles and parental confidence in their offspring on an internalizing pathway to alcohol-related problems through self-esteem and depression. Method: Mediational links were tested among parenting styles (authoritative, authoritarian, permissive), parental confidence (overprotection, autonomy), self-esteem, depression, and alcohol-related problems. A two-group, multiple indicator multiple-cause structural equation model with 441 (216 female, 225 male) college students was examined. Results: Overall, having a father who was confident in his child's ability to make autonomous decisions was protective against depression for both genders. Perceptions of paternal autonomy mediated the impact of the fathers' parenting styles (authoritative, permissive) on depression for both genders. For men, parental overprotection mediated the impact of an authoritarian father on self-esteem, and self-esteem mediated the impact of parental overprotection on depression. Moreover, among men, perceptions of maternal autonomy mediated the impact of the mothers' parenting styles (authoritative, permissive) on self-esteem, and self-esteem mediated the impact of maternal autonomy on depression. Conclusions: The current pattern of findings is distinct from pathways through behavioral undercontrol with influences from the same-sex parent for both genders. These findings indicate that parenting may have differential influences on internalizing pathways to alcohol-related problems. PMID:19261233

  16. Peering into the Brain to Predict Behavior: Peer-Reported, but not Self-Reported, Conscientiousness Links Threat-Related Amygdala Activity to Future Problem Drinking

    Science.gov (United States)

    Swartz, Johnna R.; Knodt, Annchen R.; Radtke, Spenser R.; Hariri, Ahmad R.

    2016-01-01

    Personality traits such as conscientiousness as self-reported by individuals can help predict a range of outcomes, from job performance to longevity. Asking others to rate the personality of their acquaintances often provides even better predictive power than using self-report. Here, we examine whether peer-reported personality can provide a better link between brain function, namely threat-related amygdala activity, and future health-related behavior, namely problem drinking, than self-reported personality. Using data from a sample of 377 young adult university students who were rated on five personality traits by peers, we find that higher threat-related amygdala activity to fearful facial expressions is associated with higher peer-reported, but not self-reported, conscientiousness. Moreover, higher peer-reported, but not self-reported, conscientiousness predicts lower future problem drinking more than one year later, an effect specific to men. Remarkably, relatively higher amygdala activity has an indirect effect on future drinking behavior in men, linked by peer-reported conscientiousness to lower future problem drinking. Our results provide initial evidence that the perceived conscientiousness of an individual by their peers uniquely reflects variability in a core neural mechanism supporting threat responsiveness. These novel patterns further suggest that incorporating peer-reported measures of personality into individual differences research can reveal novel predictive pathways of risk and protection for problem behaviors. PMID:27717769

  17. Peering into the brain to predict behavior: Peer-reported, but not self-reported, conscientiousness links threat-related amygdala activity to future problem drinking.

    Science.gov (United States)

    Swartz, Johnna R; Knodt, Annchen R; Radtke, Spenser R; Hariri, Ahmad R

    2017-02-01

    Personality traits such as conscientiousness as self-reported by individuals can help predict a range of outcomes, from job performance to longevity. Asking others to rate the personality of their acquaintances often provides even better predictive power than using self-report. Here, we examine whether peer-reported personality can provide a better link between brain function, namely threat-related amygdala activity, and future health-related behavior, namely problem drinking, than self-reported personality. Using data from a sample of 377 young adult university students who were rated on five personality traits by peers, we find that higher threat-related amygdala activity to fearful facial expressions is associated with higher peer-reported, but not self-reported, conscientiousness. Moreover, higher peer-reported, but not self-reported, conscientiousness predicts lower future problem drinking more than one year later, an effect specific to men. Remarkably, relatively higher amygdala activity has an indirect effect on future drinking behavior in men, linked by peer-reported conscientiousness to lower future problem drinking. Our results provide initial evidence that the perceived conscientiousness of an individual by their peers uniquely reflects variability in a core neural mechanism supporting threat responsiveness. These novel patterns further suggest that incorporating peer-reported measures of personality into individual differences research can reveal novel predictive pathways of risk and protection for problem behaviors. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Transfusion-related adverse reactions: From institutional hemovigilance effort to National Hemovigilance program

    Directory of Open Access Journals (Sweden)

    Rahul Vasudev

    2016-01-01

    Full Text Available Aims: In this study we have evaluated the various adverse reactions related to transfusion occurring in our institution as a pilot institutional effort toward a hemovigilance program. This study will also help in understanding the problems faced by blood banks/Transfusion Medicine departments in implementing an effective hemovigilance program. Materials and Methods: All the adverse reactions related to transfusion of whole blood and its components in various clinical specialties were studied for a period of 1 year. Any transfusion-related adverse event was worked up in accordance with guidelines laid down by the Directorate General of Health Services (DGHS and departmental standard operating procedures. Results: During the study period from November 1, 2011 to October 31, 2012, 45812 components were issued [30939 WB/PRBC; 12704 fresh frozen plasma (FFP; 2169 platelets]. Risk estimation per 1000 units of red cells (WB/PRBC transfused was estimated to be: 0.8 for febrile nonhemolytic transfusion reaction (FNHTR, 0.7 for allergic reaction, 0.19 for acute hemolytic transfusion reaction (AcHTR, 0.002 for anaphylactoid reactions, 0.1 for bacterial sepsis, and 0.06 for hypervolemia and hypocalcemia. 0.09 is the risk for delayed transfusion reaction and 0.03 is the risk for transfusion-related acute lung injury (TRALI. Risk estimate per 1,000 units of platelets transfused was estimated to be 1.38 for FNHTR, 1.18 for allergic reaction, and 1 in case of bacterial sepsis. Risk estimation per 1,000 units of FFP was estimated to be 0.15 for FNHTR and 0.2 for allergic reactions. Conclusions: Factors such as clerical checks at various levels, improvement in blood storage conditions outside blood banks, leukodepletion, better inventory management, careful donor screening, bedside monitoring of transfusion, and documentation of adverse events may decrease transfusion-related adverse events. Better coordination between transfusion specialists and various clinical

  19. The consequences of increasing assertiveness of trans-national religious communities for international relations

    Directory of Open Access Journals (Sweden)

    Najamudin Najamudin

    2012-12-01

    Full Text Available The transnational communities, or in other terms, the migrant communities whowent to the US and the UK, or to any other European states had strong belief intheir religion in which they might not be contaminated by the secular ideology inthe Western countries. In this respect, the phenomenology of religion in internationalrelations is a relatively new and surprising. Accordingly, this paper aims atinvestigating the implications of the emergence of trans-national religious groupsfor international relations. The paper will argue that the rise of trans-nationalreligious groups has produced a profound impact on international relations. Thefactors that influenced this transformation in international relations is the contemporaryprocesses of globalization which scholars argue, are pivotal to bringingreligion to the centre stage of international relations. In order to deepen theunderstanding of this process, two case scenarios will be analyzed, namely, theSikh Diasporas and the imagined Islamic community, the umma. In this paper, ithas been argued that the rise of trans-national religious actors may affect statesovereignty in one way or another. Under secular ideology, the role of religion ismarginalized from the public sphere, in particular, the domain of politics and religion is being obviously separated. This separation, according to both groups,is problematic. It is therefore, the emergence of Islamic and Sikh communities isconsidered by some liberal democratic countries like India as a peril to its statesovereignty. In Islamic doctrines, the Muslims hold a principle in din wa dawla,the unity of state and religion, while in Sikhism, the Sikhs have to trust miri andpiri, the unification of religious and political institution.Masyarakat transnasional atau dalam terma lain disebut juga sebagai masyarakatmigran yang menetap di Amerika dan Inggris, atau ke negara-negara Eropalainnya memiliki keyakinan yang kuat terhadap agama mereka dan

  20. Knowledge Cities and Transport Sustainability: The Link between the Travel Behavior of Knowledge Workers and Car-Related Job Perks

    DEFF Research Database (Denmark)

    Frenkel, Amnon; Bendit, Edward; Kaplan, Sigal

    2014-01-01

    from a survey among knowledge workers in Tel-Aviv. Results show that car-related job perks are associated with (1) high annual kilometrage, (2) increased commute by car, (3) long commute travel times, (4) high trip chaining frequency, and (5) many long-distance leisure trips. Results suggest......This study analyzes the linkage between the travel behavior of knowledge workers and car-related job perks. The importance of this issue derives from the tendency of knowledge economy to concentrate in highly populated metropolitan regions. The analyzed data comprise 750 observations, retrieved...... that the development of sustainable knowledge-based cities should consider decoupling knowledge workers from car-related job perks. © 2014 Copyright Taylor and Francis Group, LLC....

  1. Peer Victimization and Social Dominance as Intervening Variables of the Link between Peer Liking and Relational Aggression

    Science.gov (United States)

    Adams, Ryan E.; Bartlett, Nancy H.; Bukowski, William M.

    2010-01-01

    The current study examined social dominance and peer victimization as possible intervening and moderating variables of the association between peer liking and relational aggression because previous findings suggest that social dominance and peer victimization are important for predicting the acceptableness and success of aggression. A total of 367…

  2. Academic Procrastination in Linking Motivation and Achievement-Related Behaviours: A Perspective of Expectancy-Value Theory

    Science.gov (United States)

    Wu, Fan; Fan, Weihua

    2017-01-01

    The objective of the present study was to investigate the relationships among college students' achievement motivation (subjective task value and academic self-efficacy), academic procrastination (delay and missing deadlines) and achievement-related behaviours (effort and persistence). More specifically, the study investigated the mediating role…

  3. Bullying-related behaviour in adolescents with autism: Links with autism severity and emotional and behavioural problems

    NARCIS (Netherlands)

    Fink, Elian; Olthof, Tjeert; Goossens, Frits; van der Meijden, Sandra; Begeer, Sander

    2017-01-01

    This study examined the association between peer-reported bullying-related behaviours (bully, victim, outsider and defender), age, gender, autism severity and teacher-rated emotional and behavioural problems in adolescents with autism spectrum disorder, using a multi-informant approach. The sample

  4. The contribution of nuclear-related technical cooperation to national development

    International Nuclear Information System (INIS)

    Cook, D.

    1988-01-01

    The present situation of nuclear technical assistance and the IAEA's programs are reviewed. The perspectives of the developing and of the developed countries are discussed. Australia's aid administrators have been showing an increasing preference for administering its nuclear technical assistance through the Regional Cooperation Agreement for Asia and the Pacific (RCA), because of its direct benefits to the countries in the region, its flexibility, its emphasis on training, and its cooperative nature. The RCA also benefits from IAEA management and IAEA and United Nations Development Program funding. Two examples of Australia's successful RCA activities are the 1988 radiation protection training course held in Sydney and one of the many individual projects within the 1980-86 RCA hydrology program - the application of radioisotope tracer techniques to locating the seepage areas in the Pedu dam in Kedah State, Malaysia. Australia's experience has shown that project design, successful training of the right people, adequate infrastructure in both donor and recipient countries, and detailed post-project evaluation are the keys to successful project implementation. The RCA has achieved wide recognition as a successful tool in nuclear-related technology transfer

  5. Volcano related atmospheric toxicants in Hilo and Hawaii Volcanoes National Park: implications for human health.

    Science.gov (United States)

    Michaud, Jon-Pierre; Krupitsky, Dmitry; Grove, John S; Anderson, Bruce S

    2005-08-01

    Volcanic fog (vog) from Kilauea volcano on the island of Hawaii includes a variety of chemical species including sulfur compounds and traces of metals such as mercury. The metal species seen tended to be in the nanograms per cubic meter range, whereas oxides of sulfur: SO2 and SO3 and sulfate aerosols, were in the range of micrograms per cubic meter and rarely even as high as a few milligrams per cubic meter of air (nominally ppb to ppm). These sulfur species are being investigated for associations with both acute and chronic changes in human health status. The sulfate aerosols tend to be less than 1 microm in diameter and tend to dominate the mass of this submicron size mode. The sulfur chemistry is dynamic, changing composition from predominantly sulfur dioxide and trioxide gasses near the volcano, to predominantly sulfate aerosols on the west side of the island. Time, concentration and composition characteristics of submicron aerosols and sulfur dioxide are described with respect to the related on-going health studies and public health management concerns. Exposures to sulfur dioxide and particulate matter equal to or less than 1 microm in size were almost always below the national ambient air quality standards (NAAQS). These standards do not however consider the acidic nature and submicron size of the aerosol, nor the possibility of the aerosol and the sulfur dioxide interacting in their toxicity. Time series plots, histograms and descriptive statistics of hourly averages give the reader a sense of some of the exposures observed.

  6. Relation between the national handbook of recommended methods for water data acquisition and ASTM standards

    Science.gov (United States)

    Glysson, G. Douglas; Skinner, John V.

    1991-01-01

    In the late 1950's, intense demands for water and growing concerns about declines in the quality of water generated the need for more water-resources data. About thirty Federal agencies, hundreds of State, county and local agencies, and many private organizations had been collecting water data. However, because of differences in procedures and equipment, many of the data bases were incompatible. In 1964, as a step toward establishing more uniformity, the Bureau of the Budget (now the Office of Management and Budget, OMB) issued 'Circular A-67' which presented guidelines for collecting water data and also served as a catalyst for creating the Office of Water Data Coordination (OWDC) within the U.S. Geological Survey. This paper discusses past, present, and future aspects of the relation between methods in the National Handbook and standards published by ASTM (American Society for Testing and Materials) Committee D-19 on Water's Subcommittee D-19.07 on Sediment, Geomorphology, and Open Channel Flow. The discussion also covers historical aspects of standards - development work jointly conducted by OWDC and ASTM.

  7. German National Proficiency Scales in Biology: Internal Structure, Relations to General Cognitive Abilities and Verbal Skills

    Science.gov (United States)

    KÖLLER, OLAF

    2016-01-01

    ABSTRACT National and international large‐scale assessments (LSA) have a major impact on educational systems, which raises fundamental questions about the validity of the measures regarding their internal structure and their relations to relevant covariates. Given its importance, research on the validity of instruments specifically developed for LSA is still sparse, especially in science and its subdomains biology, chemistry, and physics. However, policy decisions for the improvement of educational quality based on LSA can only be helpful if valid information on students’ achievement levels is provided. In the present study, the nature of the measurement instruments based on the German Educational Standards in Biology is examined. On the basis of data from 3,165 students in Grade 10, we present dimensional analyses and report the relationship between different subdimensions of biology literacy and cognitive covariates such as general cognitive abilities and verbal skills. A theory‐driven two‐dimensional model fitted the data best. Content knowledge and scientific inquiry, two subdimensions of biology literacy, are highly correlated and show differential correlational patterns to the covariates. We argue that the underlying structure of biology should be incorporated into curricula, teacher training and future assessments. PMID:27818532

  8. Relative validation of a food frequency questionnaire for national health and nutrition monitoring

    Directory of Open Access Journals (Sweden)

    Haftenberger Marjolein

    2010-09-01

    Full Text Available Abstract Background Validation of a food frequency questionnaire (FFQ is important as incorrect information may lead to biased associations. Therefore the relative validity of an FFQ developed for use in the German Health Examination Survey for Adults 2008-2011 (DEGS was examined. Methods Cross-sectional comparisons of food consumption data from the FFQ and from two 24-hour recalls were made in a sample of 161 participants (aged 18 to 80 years of an ongoing nationwide survey, the German National Nutrition Monitoring (NEMONIT. The data collection took place from November 2008 to April 2009. Results Spearman rank correlations between the FFQ and the 24-hour dietary recalls ranged from 0.15 for pizza to 0.80 for tea, with two third of the correlation coefficients exceeding 0.30. All correlation coefficients were statistically significant except those for pizza and cooked vegetables. The proportion of participants classified into the same or adjacent quartile of intake assessed by both methods varied between 68% for cooked vegetables and 94% for coffee. There were no statistically significant differences in food consumption estimates between both methods for 38% of the food groups. For the other food groups, the estimates of food consumption by the FFQ were not generally higher or lower than estimates from the 24-hour dietary recalls. Conclusions The FFQ appears to be reasonably valid in the assessment of food consumption of German adults. For some food groups, such as raw and cooked vegetables, relative risks estimates should be interpreted with caution because of the poor ranking agreement.

  9. 77 FR 41447 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-07-13

    ... National Register criteria for evaluation. Comments may be forwarded by United States Postal Service, to... Independent city Manchester Industrial Historic District (Boundary Increase), Parts of Decatur, Everett, Hull...

  10. Goals and everyday problem solving: examining the link between age-related goals and problem-solving strategy use.

    Science.gov (United States)

    Hoppmann, Christiane A; Coats, Abby Heckman; Blanchard-Fields, Fredda

    2008-07-01

    Qualitative interviews on family and financial problems from 332 adolescents, young, middle-aged, and older adults, demonstrated that developmentally relevant goals predicted problem-solving strategy use over and above problem domain. Four focal goals concerned autonomy, generativity, maintaining good relationships with others, and changing another person. We examined both self- and other-focused problem-solving strategies. Autonomy goals were associated with self-focused instrumental problem solving and generative goals were related to other-focused instrumental problem solving in family and financial problems. Goals of changing another person were related to other-focused instrumental problem solving in the family domain only. The match between goals and strategies, an indicator of problem-solving adaptiveness, showed that young individuals displayed the greatest match between autonomy goals and self-focused problem solving, whereas older adults showed a greater match between generative goals and other-focused problem solving. Findings speak to the importance of considering goals in investigations of age-related differences in everyday problem solving.

  11. Questioning the link between Self-Expressed Attitudes and Repurchasing Behavior: Relations Between Cognitive, Affective and Action Loyalty

    Directory of Open Access Journals (Sweden)

    Guven Ordun

    2015-04-01

    Full Text Available In psychology attitude is defined as favorable or unfavorable evaluations towards a person, group, object or event. Attitudes are formed by past and present experiences and are expected to change as a function of experience. Three components of the attitude defined as cognitive (what we know about the subject, affective (how we feel towards the subject and behavioral (intention to behave towards the subject. Our behavior is defined as a complex combination of beliefs, feelings, capabilities and norms. The majority of consumer behavior literature examined the main antecedents of purchase behavior. Attitudes are described as one of the most important determinant of the behavior. There are several methods and techniques to assess attitude; the most used one is the self-report paper and pencil measures. Brand loyalty is another important concept related with repetitive purchasing behavior. While cognitive loyalty is related with the information, affective loyalty is related with feelings. Behavioral loyalty is described as the past behaviors or experiences. Some of our behaviors are determined by the cognitive component of the attitude while others may be directed by the affective part. Main focus of the research is to find out whether there is a level of compliance between cognitive, affective and behavioral attitude of consumers. 1000 forms are distributed in order to identify the attitudes and purchasing behaviors of consumers 783 forms are evaluated

  12. Questioning the Link between Self-Expressed Attitudes and Repurchasing Behavior: Relations Between Cognitive, Affective and Action Loyalty

    Directory of Open Access Journals (Sweden)

    Guven Ordun

    2016-01-01

    Full Text Available In psychology attitude is defined as favorable or unfavorable evaluations towards a person, group, object or event. Attitudes are formed by past and present experiences and are expected to change as a function of experience. Three components of the attitude defined as cognitive (what we know about the subject, affective (how we feel towards the subject and behavioral (intention to behave towards the subject. Our behavior is defined as a complex combination of beliefs, feelings, capabilities and norms. The majority of consumer behavior literature examined the main antecedents of purchase behavior. Attitudes are described as one of the most important determinant of the behavior. There are several methods and techniques to assess attitude; the most used one is the self-report paper and pencil measures. Brand loyalty is another important concept related with repetitive purchasing behavior. While cognitive loyalty is related with the information, affective loyalty is related with feelings. Behavioral loyalty is described as the past behaviors or experiences. Some of our behaviors are determined by the cognitive component of the attitude while others may be directed by the affective part. Main focus of the research is to find out whether there is a level of compliance between cognitive, affective and behavioral attitude of consumers. 1000 forms are distributed in order to identify the attitudes and purchasing behaviors of consumers 783 forms are evaluated

  13. Activity-related parenting practices: development of the Parenting Related to Activity Measure (PRAM) and links with mothers' eating psychopathology and compulsive exercise beliefs.

    Science.gov (United States)

    Haycraft, Emma; Powell, Faye; Meyer, Caroline

    2015-01-01

    This is a two-study paper that developed a measure to assess parenting practices related to children's physical activity and explored maternal predictors of such parenting practices. Study 1: A self-report measure of parents' activity-related practices (the Parenting Related to Activity Measure) was developed, and a principal component analysis was carried out using data from 233 mothers of 4.5- to 9-year-old children. The results supported a six-factor model and yielded the following subscales: Responsibility/monitoring; Activity regulation; Control of active behaviours; Overweight concern; Rewarding parenting; and Pressure to exercise. Study 2: Mothers (N = 170) completed the Parenting Related to Activity Measure, alongside measures of eating psychopathology and compulsive exercise, to identify predictors of activity-related parenting practices. Mothers' eating psychopathology and exercise beliefs predicted activity parenting practices with their sons and daughters, but different predictors were seen for mothers of daughters versus sons. Mothers' eating and exercise attitudes are important predictors of their activity-related parenting practices, particularly with girls. Identifying early interactions around activity/exercise could be important in preventing the development of problematic beliefs about exercise, which are often a key symptom of eating disorders. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.

  14. Patterns of Alcohol Consumption and Related Behaviors in Brazil: Evidence from the 2013 National Health Survey (PNS 2013)

    OpenAIRE

    Macinko, James; Mullachery, Pricila; Silver, Diana; Jimenez, Geronimo; Libanio Morais Neto, Otaliba

    2015-01-01

    © 2015 Macinko et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This study uses data from a nationally representative household survey (the 2013 National Health Survey, n = 62,986) to describe patterns of alcohol consumption and related behaviors among Brazilian adults. Analyses include descriptive and...

  15. SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1.

    Science.gov (United States)

    Anafi, M; Kiefer, F; Gish, G D; Mbamalu, G; Iscove, N N; Pawson, T

    1997-10-31

    Ste20-related protein kinases have been implicated as regulating a range of cellular responses, including stress-activated protein kinase pathways and the control of cytoskeletal architecture. An important issue involves the identities of the upstream signals and regulators that might control the biological functions of mammalian Ste20-related protein kinases. HPK1 is a protein-serine/threonine kinase that possesses a Ste20-like kinase domain, and in transfected cells activates a protein kinase pathway leading to the stress-activated protein kinase SAPK/JNK. Here we have investigated candidate upstream regulators that might interact with HPK1. HPK1 possesses an N-terminal catalytic domain and an extended C-terminal tail with four proline-rich motifs. The SH3 domains of Grb2 bound in vitro to specific proline-rich motifs in the HPK1 tail and functioned synergistically to direct the stable binding of Grb2 to HPK1 in transfected Cos1 cells. Epidermal growth factor (EGF) stimulation did not affect the binding of Grb2 to HPK1 but induced recruitment of the Grb2.HPK1 complex to the autophosphorylated EGF receptor and to the Shc docking protein. Several activated receptor and cytoplasmic tyrosine kinases, including the EGF receptor, stimulated the tyrosine phosphorylation of the HPK1 serine/threonine kinase. These results suggest that HPK1, a mammalian Ste20-related protein-serine/threonine kinase, can potentially associate with protein-tyrosine kinases through interactions mediated by SH2/SH3 adaptors such as Grb2. Such interaction may provide a possible mechanism for cross-talk between distinct biochemical pathways following the activation of tyrosine kinases.

  16. Linking black hole growth with host galaxies: the accretion-stellar mass relation and its cosmic evolution

    Science.gov (United States)

    Yang, G.; Brandt, W. N.; Vito, F.; Chen, C.-T. J.; Trump, J. R.; Luo, B.; Sun, M. Y.; Xue, Y. Q.; Koekemoer, A. M.; Schneider, D. P.; Vignali, C.; Wang, J.-X.

    2018-04-01

    Previous studies suggest that the growth of supermassive black holes (SMBHs) may be fundamentally related to host-galaxy stellar mass (M⋆). To investigate this SMBH growth-M⋆ relation in detail, we calculate long-term SMBH accretion rate as a function of M⋆ and redshift [\\overlineBHAR(M_{\\star }, z)] over ranges of log (M⋆/M⊙) = 9.5-12 and z = 0.4-4. Our \\overlineBHAR(M_{\\star }, z) is constrained by high-quality survey data (GOODS-South, GOODS-North and COSMOS), and by the stellar mass function and the X-ray luminosity function. At a given M⋆, \\overlineBHAR is higher at high redshift. This redshift dependence is stronger in more massive systems [for log (M⋆/M⊙) ≈ 11.5, \\overlineBHAR is three decades higher at z = 4 than at z = 0.5], possibly due to AGN feedback. Our results indicate that the ratio between \\overlineBHAR and average star formation rate (\\overlineSFR) rises towards high M⋆ at a given redshift. This \\overlineBHAR/\\overlineSFR dependence on M⋆ does not support the scenario that SMBH and galaxy growth are in lockstep. We calculate SMBH mass history [MBH(z)] based on our \\overlineBHAR(M_{\\star }, z) and the M⋆(z) from the literature, and find that the MBH-M⋆ relation has weak redshift evolution since z ≈ 2. The MBH/M⋆ ratio is higher towards massive galaxies: it rises from ≈1/5000 at log M⋆ ≲ 10.5 to ≈1/500 at log M⋆ ≳ 11.2. Our predicted MBH/M⋆ ratio at high M⋆ is similar to that observed in local giant ellipticals, suggesting that SMBH growth from mergers is unlikely to dominate over growth from accretion.

  17. Operative Links

    DEFF Research Database (Denmark)

    Wistoft, Karen; Højlund, Holger

    2012-01-01

    educational goals, learning content, or value clarification. Health pedagogy is often a matter of retrospective rationalization rather than the starting point of planning. Health and risk behaviour approaches override health educational approaches. Conclusions: Operational links between health education......, health professionalism, and management strategies pose the foremost challenge. Operational links indicates cooperative levels that facilitate a creative and innovative effort across traditional professional boundaries. It is proposed that such links are supported by network structures, shared semantics...

  18. The mediating role of work-related musculoskeletal disorders on the link between psychosocial factors and absenteeism among administrative workers.

    Science.gov (United States)

    Abdullah, Mohd Zulkifli; Othman, Abdul Kadir; Ahmad, Mohamad Fahimi; Justine, Maria

    2015-01-01

    This study aimed to investigate the association between psychosocial factors (i.e., job demand, decision latitude, social support, physical environment, and personal risk factors), work-related musculoskeletal disorders (WRMDs), and productivity as measured by workers' perceived absenteeism. Data were collected from the selected administrative workers (administrative assistant) and analyzed using cross tabulation. The results indicate that all psychological factors are not significantly associated with WRMDs, except for the association between personal risk factors and hip/thigh disorders. Subsequently, WRMDs do not significantly contribute to explaining absenteeism. The managerial and research implications of this study are deliberately discussed.

  19. 76 FR 43342 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-07-20

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-WASO-NRNHL-0611-7822; 2280-665] National... 19th and Early 20th Century Development and Architecture in Pasadena MPS), 438-516 Cypress Ave... Architecture in Pasadena MPS), 510 Locke Haven St., Pasadena, 11000490. Denham, Mary E., House (Late 19th and...

  20. Children's Development of Concepts Related to Country and Nationality: A Canadian Perspective.

    Science.gov (United States)

    Brown, James A.

    1980-01-01

    Canadian children follow an apparent sequence in the development of a concept of nationality from a verbal level of understanding of geographical relationships (beginning about age six), to an ability to demonstrate spatial relationships, then to an understanding of one's nationality, at about age 10. There are important educational implications.…

  1. Evaluating a National Science and Technology Program Using the Human Capital and Relational Asset Perspectives

    Science.gov (United States)

    Hung, Chia-Liang; Chou, Jerome Chih-Lung; Roan, Hung-Wei

    2010-01-01

    The purpose of this research is to evaluate the performance of the National Science and Technology Program (NSTP) by targeting the Taiwan National Telecommunication Program (NTP) initiated in 1998. The Taiwan telecommunications industry has prospered, currently occupying key positions in global markets even though NTP seldom contributes positively…

  2. Linking Indigenous Peoplesr Health-Related Decision Making to Information Communication Technology: Insights from an Emerging Economy

    Directory of Open Access Journals (Sweden)

    Md. Jahir Uddin Palas

    2017-04-01

    Full Text Available Indigenous peoples are being marginalised globally from a socioeconomic perspective and are often excluded from mainstream communities for social and/or geographic reasons. Historically, they tend to have lower living standards, including poor health conditions as compared to the rest of the population. Literature suggests that information and communication technologies (ICTs have the potential to improve awareness about how to improve health and wellbeing. In order to both deepen and broaden the understanding of how ICTs can influence Indigenous peoplesr health-related decision-making, this study has developed a conceptual framework based on the capability approach, focusing on the five dimensions of freedoms suggested by Amartya Sen. Data collected from a sample of members of an Indigenous community in Bangladesh, using a purposive sampling method, were analysed through qualitative techniques to identify ways in which a mobile-based health system have influenced the lives of indigenous people. The findings revealed that the mobile healthcare system explored in this study addressed a number of factors pertaining to indigenous peoplesr quality of life. These findings are useful for policy formulation related to the design and implementation of healthcare strategies in Bangladesh. The conceptual framework, following further validation, could serve as a platform for the advancement of research towards understanding how mobile healthcare systems can improve the wellbeing of individuals in indigenous communities.

  3. Proceedings of the fifth national symposium on environment: focal theme environmental issues related to mining, milling and metallurgy

    International Nuclear Information System (INIS)

    Sastry, V.N.; Bapat, V.N.; Desai, M.V.M.

    1996-02-01

    The fifth National Symposium on Environment was held in Calcutta from February 28 to March 1, 1996. It focused on environmental issues related to mining, milling and metallurgy. Some of the topics covered are coal mining and related environmental issues, chromium mining and associated environmental problems, heavy metals especially nuclear materials and the environmental management strategies, arsenic contamination in water in West Bengal areas and radiological issues related to fertilizers and gypsum industries. Papers relevant to INIS are indexed separately. refs., figs., tabs

  4. 78 FR 43916 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-07-22

    ...) Ave. P, .75 mi. W. of 30th Rd., Little River, 13000580 Santa Fe Trail--Rice County Segment 3, (Santa... MISSOURI St. Charles County Link, Oliver L. and Catherine, House, 1005 Jefferson, St. Charles, 13000584 NEW... Manitowoc County Klingholz, Charles and Herriette, House, 224 Mill Rd., Manitowoc Rapids, 13000587 Waukesha...

  5. Emergency Medical Services (EMS) Public Information, Education and Relations (PIER): National Standard Curriculum (Administrator's Guide)

    Science.gov (United States)

    1997-01-01

    Imagine a transportation network linked by information and technology that makes travel quicker, safer and easier. Imagine being able to plot your route before you leave your home or office and know exactly how long it will take you - by car, subway ...

  6. Lung Cancer Cell Line Screen Links Fanconi Anemia/BRCA Pathway Defects to Increased Relative Biological Effectiveness of Proton Radiation

    International Nuclear Information System (INIS)

    Liu, Qi; Ghosh, Priyanjali; Magpayo, Nicole; Testa, Mauro; Tang, Shikui; Gheorghiu, Liliana; Biggs, Peter; Paganetti, Harald; Efstathiou, Jason A.; Lu, Hsiao-Ming; Held, Kathryn D.; Willers, Henning

    2015-01-01

    Purpose: Growing knowledge of genomic heterogeneity in cancer, especially when it results in altered DNA damage responses, requires re-examination of the generic relative biological effectiveness (RBE) of 1.1 of protons. Methods and Materials: For determination of cellular radiosensitivity, we irradiated 17 lung cancer cell lines at the mid-spread-out Bragg peak of a clinical proton beam (linear energy transfer, 2.5 keV/μm). For comparison, 250-kVp X rays and 137 Cs γ-rays were used. To estimate the RBE of protons relative to 60 Co (Co60eq), we assigned an RBE(Co60Eq) of 1.1 to X rays to correct the physical dose measured. Standard DNA repair foci assays were used to monitor damage responses. FANCD2 was depleted using RNA interference. Results: Five lung cancer cell lines (29.4%) exhibited reduced clonogenic survival after proton irradiation compared with X-irradiation with the same physical doses. This was confirmed in a 3-dimensional sphere assay. Corresponding proton RBE(Co60Eq) estimates were statistically significantly different from 1.1 (P≤.05): 1.31 to 1.77 (for a survival fraction of 0.5). In 3 of these lines, increased RBE was correlated with alterations in the Fanconi anemia (FA)/BRCA pathway of DNA repair. In Calu-6 cells, the data pointed toward an FA pathway defect, leading to a previously unreported persistence of proton-induced RAD51 foci. The FA/BRCA-defective cells displayed a 25% increase in the size of subnuclear 53BP1 foci 18 hours after proton irradiation. Conclusions: Our cell line screen has revealed variations in proton RBE that are partly due to FA/BRCA pathway defects, suggesting that the use of a generic RBE for cancers should be revisited. We propose that functional biomarkers, such as size of residual 53BP1 foci, may be used to identify cancers with increased sensitivity to proton radiation

  7. Lung Cancer Cell Line Screen Links Fanconi Anemia/BRCA Pathway Defects to Increased Relative Biological Effectiveness of Proton Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Qi; Ghosh, Priyanjali; Magpayo, Nicole [Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Testa, Mauro; Tang, Shikui [Division of Radiation Physics, Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Gheorghiu, Liliana [Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Biggs, Peter; Paganetti, Harald [Division of Radiation Physics, Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Efstathiou, Jason A. [Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Lu, Hsiao-Ming [Division of Radiation Physics, Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Held, Kathryn D. [Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Willers, Henning, E-mail: hwillers@mgh.harvard.edu [Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)

    2015-04-01

    Purpose: Growing knowledge of genomic heterogeneity in cancer, especially when it results in altered DNA damage responses, requires re-examination of the generic relative biological effectiveness (RBE) of 1.1 of protons. Methods and Materials: For determination of cellular radiosensitivity, we irradiated 17 lung cancer cell lines at the mid-spread-out Bragg peak of a clinical proton beam (linear energy transfer, 2.5 keV/μm). For comparison, 250-kVp X rays and {sup 137}Cs γ-rays were used. To estimate the RBE of protons relative to {sup 60}Co (Co60eq), we assigned an RBE(Co60Eq) of 1.1 to X rays to correct the physical dose measured. Standard DNA repair foci assays were used to monitor damage responses. FANCD2 was depleted using RNA interference. Results: Five lung cancer cell lines (29.4%) exhibited reduced clonogenic survival after proton irradiation compared with X-irradiation with the same physical doses. This was confirmed in a 3-dimensional sphere assay. Corresponding proton RBE(Co60Eq) estimates were statistically significantly different from 1.1 (P≤.05): 1.31 to 1.77 (for a survival fraction of 0.5). In 3 of these lines, increased RBE was correlated with alterations in the Fanconi anemia (FA)/BRCA pathway of DNA repair. In Calu-6 cells, the data pointed toward an FA pathway defect, leading to a previously unreported persistence of proton-induced RAD51 foci. The FA/BRCA-defective cells displayed a 25% increase in the size of subnuclear 53BP1 foci 18 hours after proton irradiation. Conclusions: Our cell line screen has revealed variations in proton RBE that are partly due to FA/BRCA pathway defects, suggesting that the use of a generic RBE for cancers should be revisited. We propose that functional biomarkers, such as size of residual 53BP1 foci, may be used to identify cancers with increased sensitivity to proton radiation.

  8. Pain Processing in a Social Context and the Link with Psychopathic Personality Traits—An Event-Related Potential Study

    Directory of Open Access Journals (Sweden)

    Casper H. van Heck

    2017-09-01

    Full Text Available Empathy describes the ability to understand another person’s feelings. Psychopathy is a disorder that is characterized by a lack of empathy. Therefore, empathy and psychopathy are interesting traits to investigate with respect to experiencing and observing pain. The present study aimed to investigate pain empathy and pain sensitivity by measuring event-related potentials (ERPs extracted from the ongoing EEG in an interactive setup. Each participant fulfilled subsequently the role of “villain” and “victim”. In addition, mode of control was modulated resulting in four different conditions; passive villain, active villain, active victim and passive victim. Response-, visual- and pain ERPs were compared between the four conditions. Furthermore, the role of psychopathic traits in these outcomes was investigated. Our findings suggested that people experience more conflict when hurting someone else than hurting themselves. Furthermore, our results indicated that self-controlled pain was experienced as more painful than uncontrolled pain. People that scored high on psychopathic traits seemed to process and experience pain differently. According to the results of the current study, social context, attention and personality traits seem to modulate pain processing and the empathic response to pain in self and others. The within-subject experimental design described here provides an excellent approach to further unravel the influence of social context and personality traits on social cognition.

  9. Children and Nature: Linking Accessibility of Natural Environments and Children’s Health-Related Quality of Life

    Directory of Open Access Journals (Sweden)

    Suzanne Tillmann

    2018-05-01

    Full Text Available A growing body of research suggests that increasing children’s nature interactions can have positive benefits for their health-related quality of life (HRQOL; however, researchers have yet to examine how geographical context influences this relationship. The purpose of this study was to examine individual-level and environmental factors that are associated with HRQOL of children from different geographical contexts. Data were collected for 851 children from 34 elementary schools in Ontario, Canada. The natural environments around each child’s home were computed using geospatial analyses in a geographic information system. Natural environment measures were combined with HRQOL and the demographics from child surveys to be used in a series of step-wise linear regression models. These models explored the relationship between children’s HRQOL and the natural environment in urban/suburban and rural populations. In addition to important individual-level determinants, the findings revealed that characteristics of the natural environment, including the amount of greenness, park, and water, show significant relationships in the urban/suburban population. Interpersonal variables were the key predictors of HRQOL in the rural population. Where children live influences relationships between nature and HRQOL. These findings have implications for policymakers, health practitioners, educators, and parents in the design and the promotion of nature for children’s HRQOL.

  10. Relation between enzyme-linked immunosorbent assay and radioimmunoassay for detection of antibodies to the capsular polysaccharide of Haemophilus influenzae type b

    International Nuclear Information System (INIS)

    Kristensen, K.; Weis Bentzon, M.

    1992-01-01

    The measurement of antibodies to the capsular polysaccharide (PRP) of Haemophilus influenzae type b (Hib) is important because vaccines inducing such antibodies are now available. We developed and evaluated an enzyme-linked immunosorbent assay (ELISA) for detection of these antibodies based on direct coating of the plates with tyraminated PRP. The assay fulfilled the requirements for parallel line assays; it was sensitive, specific, and reproducible with a coefficient of variation between days of 19%. Results from the ELISA were compared with results from radioimmunoassay and a correlation coefficient of 0.93 was found. Results obtained by the two methods were proportional and the relation was indepenedent of the antibody level. The relation between them was also unaffected by the contribution of different antibody isotypes, indicating that these were measured to the same extent by both methods. ELISA employing direct coating of the plates with tyraminated PRP represents a useful alternative for detection of antibodies when studying immunogenicity of Hib vaccines. (au)

  11. Weierstrass polynomials for links

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    1997-01-01

    There is a natural way of identifying links in3-space with polynomial covering spaces over thecircle. Thereby any link in 3-space can be definedby a Weierstrass polynomial over the circle. Theequivalence relation for covering spaces over thecircle is, however, completely different from...

  12. 15th March 2011 - Singapore National Research Foundation Permanent Secretary(National Research and Development)T. M. Kian signing the guest book with Head of International Relations F. Pauss and visiting CMS control centre with Collaboration Spokesperson G. Tonelli.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    15th March 2011 - Singapore National Research Foundation Permanent Secretary(National Research and Development)T. M. Kian signing the guest book with Head of International Relations F. Pauss and visiting CMS control centre with Collaboration Spokesperson G. Tonelli.

  13. Development and field testing of satellite-linked fluorometers for marine mammals

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset includes telemetry data related to the development and testing of an animal-borne satellite-linked fluorometer tag, used on northern fur seals and...

  14. 78 FR 14356 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-03-05

    ... properties under the National Register criteria for evaluation. Comments may be forwarded by United States... Tobacco Storage Warehouse, 1211 Manchester St., Lexington, 13000110 Kenton County Ludlow Theater, The, 322...

  15. 77 FR 56231 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-09-12

    ... National Register criteria for evaluation. Comments may be forwarded by United States Postal Service, to... Hook, 12000831 Rensselaer County Cornell--Manchester Farmstead, (Farmsteads of Pittstown, New York MPS...

  16. 77 FR 19694 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-04-02

    ... under the National Register criteria for evaluation. Comments may be forwarded by United States Postal... in the United States, 1830-1960 MPS) Roughly bounded by Armour Blvd., The Paseo, 39th St., & Troost...

  17. 78 FR 44149 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-07-23

    ... guarantee that we will be able to do so. Dated: July 5, 2013. J. Paul Loether, Chief, National Register of..., 13000591 COLORADO Logan County Downtown Sterling Historic District, Roughly bounded by Division Ave...

  18. 76 FR 24050 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-04-29

    ... guarantee that we will be able to do so. J. Paul Loether, Chief, National Register of Historic Places... Logan County Booneville Methodist Episcopal Church South, 355 N. Broadway, Booneville, 11000301 Prairie...

  19. 77 FR 29681 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-05-18

    ... guarantee that we will be able to do so. J. Paul Loether, Chief, National Register of Historic Places..., 12000324 Belvidere South State Street Historic District, State St. between Logan Ave. & Madison St...

  20. 77 FR 51566 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-08-24

    ... guarantee that we will be able to do so. Dated: August 1, 2012. J. Paul Loether, Chief, National Register of... Bexar County Hays Street Bridge, (Historic Bridges of Texas MPS) Hays St. over UPRR, N. Cherry...

  1. 77 FR 57114 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-09-17

    ... guarantee that we will be able to do so. Dated: August 29, 2012. J. Paul Loether, Chief, National Register... Brown County Christ Episcopal Church Complex, 425 Cherry St., Green Bay, 12000852 A request for removal...

  2. 77 FR 3280 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-01-23

    ... review, we cannot guarantee that we will be able to do so. J. Paul Loether, Chief, National Register of... Goodhue County Oakwood Cemetery, 1258 Cherry St., Red Wing, 12000005 Kandiyohi County Lakeland Hotel, 407...

  3. 76 FR 66323 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-10-26

    ... guarantee that we will be able to do so. J. Paul Loether, Chief, National Register of Historic Places..., Roughly bounded by Ewing, Park & Cherry Sts., Guthrie, 11000801 Warren County Hardcastle Store, The, 7286...

  4. 75 FR 4415 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-01-27

    ... comments should be submitted by Dated: February 11, 2010. J. Paul Loether, Chief, National Register of... Building, 125 Cherry St., Buffalo, 10000027 Montgomery County Chalmers Knitting Mills, 21-41 Bridge St...

  5. 75 FR 3246 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-01-20

    ... comments should be submitted by February 4, 2010. J. Paul Loether, Chief, National Register of Historic...., Spencer, 10000002 Wapello County Garner, J.W., Building, (Ottumwa MPS) 222-224 E. 2nd St., Ottumwa...

  6. Missing Rings in Pinus halepensis – The Missing Link to Relate the Tree-Ring Record to Extreme Climatic Events

    Science.gov (United States)

    Novak, Klemen; de Luis, Martin; Saz, Miguel A.; Longares, Luis A.; Serrano-Notivoli, Roberto; Raventós, Josep; Čufar, Katarina; Gričar, Jožica; Di Filippo, Alfredo; Piovesan, Gianluca; Rathgeber, Cyrille B. K.; Papadopoulos, Andreas; Smith, Kevin T.

    2016-01-01

    Climate predictions for the Mediterranean Basin include increased temperatures, decreased precipitation, and increased frequency of extreme climatic events (ECE). These conditions are associated with decreased tree growth and increased vulnerability to pests and diseases. The anatomy of tree rings responds to these environmental conditions. Quantitatively, the width of a tree ring is largely determined by the rate and duration of cell division by the vascular cambium. In the Mediterranean climate, this division may occur throughout almost the entire year. Alternatively, cell division may cease during relatively cool and dry winters, only to resume in the same calendar year with milder temperatures and increased availability of water. Under particularly adverse conditions, no xylem may be produced in parts of the stem, resulting in a missing ring (MR). A dendrochronological network of Pinus halepensis was used to determine the relationship of MR to ECE. The network consisted of 113 sites, 1,509 trees, 2,593 cores, and 225,428 tree rings throughout the distribution range of the species. A total of 4,150 MR were identified. Binomial logistic regression analysis determined that MR frequency increased with increased cambial age. Spatial analysis indicated that the geographic areas of south-eastern Spain and northern Algeria contained the greatest frequency of MR. Dendroclimatic regression analysis indicated a non-linear relationship of MR to total monthly precipitation and mean temperature. MR are strongly associated with the combination of monthly mean temperature from previous October till current February and total precipitation from previous September till current May. They are likely to occur with total precipitation lower than 50 mm and temperatures higher than 5°C. This conclusion is global and can be applied to every site across the distribution area. Rather than simply being a complication for dendrochronology, MR formation is a fundamental response of trees

  7. Missing Rings in Pinus halepensis - The Missing Link to Relate the Tree-Ring Record to Extreme Climatic Events.

    Science.gov (United States)

    Novak, Klemen; de Luis, Martin; Saz, Miguel A; Longares, Luis A; Serrano-Notivoli, Roberto; Raventós, Josep; Čufar, Katarina; Gričar, Jožica; Di Filippo, Alfredo; Piovesan, Gianluca; Rathgeber, Cyrille B K; Papadopoulos, Andreas; Smith, Kevin T

    2016-01-01

    Climate predictions for the Mediterranean Basin include increased temperatures, decreased precipitation, and increased frequency of extreme climatic events (ECE). These conditions are associated with decreased tree growth and increased vulnerability to pests and diseases. The anatomy of tree rings responds to these environmental conditions. Quantitatively, the width of a tree ring is largely determined by the rate and duration of cell division by the vascular cambium. In the Mediterranean climate, this division may occur throughout almost the entire year. Alternatively, cell division may cease during relatively cool and dry winters, only to resume in the same calendar year with milder temperatures and increased availability of water. Under particularly adverse conditions, no xylem may be produced in parts of the stem, resulting in a missing ring (MR). A dendrochronological network of Pinus halepensis was used to determine the relationship of MR to ECE. The network consisted of 113 sites, 1,509 trees, 2,593 cores, and 225,428 tree rings throughout the distribution range of the species. A total of 4,150 MR were identified. Binomial logistic regression analysis determined that MR frequency increased with increased cambial age. Spatial analysis indicated that the geographic areas of south-eastern Spain and northern Algeria contained the greatest frequency of MR. Dendroclimatic regression analysis indicated a non-linear relationship of MR to total monthly precipitation and mean temperature. MR are strongly associated with the combination of monthly mean temperature from previous October till current February and total precipitation from previous September till current May. They are likely to occur with total precipitation lower than 50 mm and temperatures higher than 5°C. This conclusion is global and can be applied to every site across the distribution area. Rather than simply being a complication for dendrochronology, MR formation is a fundamental response of trees

  8. Going against the flow: a critical analysis of inter-state virtual water trade in the context of India's national river linking programme

    NARCIS (Netherlands)

    Verma, Shilp; Kampman, Doeke A.; van der Zaag, Pieter; Hoekstra, Arjen Ysbert

    2009-01-01

    Virtual water trade has been promoted as a tool to address national and regional water scarcity. In the context of international (food) trade, this concept has been applied with a view to optimize the flow of commodities considering the water endowments of nations. The concept states that water rich

  9. Using the Internet for Health-Related Activities: Findings From a National Probability Sample

    Science.gov (United States)

    Saperstein, Sandra L; Pleis, John

    2009-01-01

    Background eHealth tools on the Internet have the potential to help people manage their health and health care. However, little is known about the distribution and use of different kinds of eHealth tools across the population or within population subgroups. Objective The purpose of this study was to examine the prevalence and predictors of participation in specific online health-related activities. Methods A secondary data analysis of the National Cancer Institute’s Health Information National Trends Survey (HINTS) 2005 was conducted to study three online behaviors among Internet users (n = 3244): searching for health information for oneself, participating in a support group for those with similar health or medical conditions, and purchasing medicine or vitamins. Results A total of 58% of Internet users reported searching for health information for themselves, 3.8% used online support groups, and 12.8% bought medicine or vitamins online in the past year. Multivariate analysis found that those seeking health information were more likely to be women (OR = 2.23, 95% CI = 1.60, 3.09), have cable or satellite Internet connections (OR = 1.73, 95% CI = 1.22, 2.45) or DSL connections (OR = 1.94, 95% CI = 1.36, 2.76), have Internet access from work (OR = 2.43, 95% CI = 1.27, 4.67) or from home and work (OR = 1.73, 95% CI = 1.31, 2.30), and report more hours of weekday Internet use (OR = 4.12, 95% CI = 2.41, 7.07). Those with a high school education or less (OR = 0.44, 95% CI = 0.31, 0.63) and those with some college (OR = 0.66, 95% CI = 0.49, 0.89) were less likely to search for health information. Online support groups were more likely to be used by those with “fair” health (OR = 3.28, 95% CI = 1.21, 8.92) and “poor” health (OR = 5.98, 95% CI = 1.49, 24.07) and those with lower incomes (OR = 2.64, 95% CI = 1.09, 6.41) and less likely to be used by those with Internet access both at home and work (OR = 0.56, 95% CI = 0.35, 0.90). Those who were age 35-49 (OR = 2

  10. An analysis of national and cross-national consumer segments using the food-related lifestyle instrument in Denmark, France, Germany and the United Kingdom

    DEFF Research Database (Denmark)

    Bredahl, Lone; Grunert, Klaus G.

    1996-01-01

    Food markets are claimed to be characterized by two opposing tendencies: On the one hand, food culture seems to be a domain of increasingly transnational character. On the other hand, there is substantial evidence that food culture has considerabl inertia. This papers reports a series of studies...... aimed at investigating whether cross-national food consumer segments can be found. Food consumer segments are derived using the food-related lifestyle instrument, which characterizes consumers by ho employ food and eating to obtain life values. The instrument, which has been developed especially...... have at least weak cross-cultural comparability. Nation-wise cluster analysis using Ward method yielded sets of five or six segments per country. The segments were named the uninvolved, the careless, the rational, the conservative, and the adventurous food consumers. A comparison of the segment...

  11. An analysis of national and cross-national consumer segments using the food-related lifestyle instrument in Denmark, France, Germany and Great Britain

    DEFF Research Database (Denmark)

    Brunsø, Karen; Grunert, Klaus G.; Bredahl, Lone

    Executive summary 1. Food markets are claimed to be characterized by two opposing tendencies. On the one hand, food culture seems to be a domain of increasingly transnational character. On the other hand, there is substantial evidence that food culture has considerable inertia. This paper reports...... a series of studies aimed at investigating whether cross-national food consumer segments can be found. 2. Food consumer segments are derived using the food-related lifestyle instrument, which characterizes consumers by how they employ food and eating to obtain life values. The instrument, which has been...... of cross-cultural comparability. 5. Nation-wise cluster analysis using Ward's method yielded sets of five or six segments per country. The segments were labelled the uninvolved food consumer, the careless food consumer, the rational food consumer, the conservative food consumer, the adventurous consumer...

  12. Roles of body image-related experiential avoidance and uncommitted living in the link between body image and women's quality of life.

    Science.gov (United States)

    Trindade, Inês A; Ferreira, Cláudia; Pinto-Gouveia, José

    2018-01-01

    The current study aimed to test whether the associations of body mass index, body image discrepancy, and social comparison based on physical appearance with women's psychological quality of life (QoL) would be explained by the mechanisms of body image-related experiential avoidance and patterns of uncommitted living. The sample was collected from October 2014 to March 2015 and included 737 female college students (aged between 18 and 25 years) who completed validated self-report measures. Results demonstrated that the final path model explained 43% of psychological QoL and revealed an excellent fit. Body image-related experiential avoidance had a meditational role in the association between body image discrepancy and psychological QoL. Further, the link between social comparison based on physical appearance and psychological QoL was partially mediated by body image-related experiential avoidance and uncommitted living. These findings indicate that the key mechanisms of the relationship between body image and young women's QoL were those related to maladaptive emotion regulation. It thus seems that interventions aiming to promote mental health in this population should promote acceptance of internal experiences related to physical appearance (e.g., sensations, thoughts, or emotions) and the engagement in behaviors committed to life values.

  13. Proxy and patient reports of health-related quality of life in a national cancer survey.

    Science.gov (United States)

    Roydhouse, Jessica K; Gutman, Roee; Keating, Nancy L; Mor, Vincent; Wilson, Ira B

    2018-01-05

    Proxy respondents are frequently used in surveys, including those assessing health-related quality of life (HRQOL). In cancer, most research involving proxies has been undertaken with paired proxy-patient populations, where proxy responses are compared to patient responses for the same individual. In these populations, proxy-patient differences are small and suggest proxy underestimation of patient HRQOL. In practice, however, proxy responses will only be used when patient responses are not available. The difference between proxy and patient reports of patient HRQOL where patients are not able to report for themselves in cancer is not known. The objective of this study was to evaluate the difference between patient and proxy reports of patient HRQOL in a large national cancer survey, and determine if this difference could be mitigated by adjusting for clinical and sociodemographic information about patients. Data were from the Cancer Care Outcomes Research and Surveillance (CanCORS) study. Patients or their proxies were recruited within 3-6 months of diagnosis with lung or colorectal cancer. HRQOL was measured using the SF-12 mental and physical composite scales. Differences of ½ SD (=5 points) were considered clinically significant. The primary independent variable was proxy status. Linear regression models were used to adjust for patient sociodemographic and clinical covariates, including cancer stage, patient age and education, and patient co-morbidities. Of 6471 respondents, 1011 (16%) were proxies. Before adjustment, average proxy-reported scores were lower for both physical (-6.7 points, 95% CI -7.4 to -5.9) and mental (-6 points, 95% CI -6.7 to -5.2) health. Proxy-reported scores remained lower after adjustment (physical: -5.8 points, -6.6 to -5; mental: -5.8 points, -6.6 to 5). Proxy-patient score differences remained clinically and statistically significant, even after adjustment for sociodemographic and clinical variables. Proxy-reported outcome scores

  14. Managing EHS of PV-Related Equipment at the National Renewable Energy Laboratory: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    McCuskey, T.; Nelson, B. P.

    2012-06-01

    Managing environment, health, and safety (EHS) risks at a national laboratory, or university, can be intimidating to a researcher who is focused on research results. Laboratory research and development (R&D) operations are often driven by scientists with limited engineering support and lack well-refined equipment development resources. To add to the burden for a researcher, there is a plethora of codes, standards, and regulations that govern the safe installation and operation of photovoltaic-related R&D equipment -- especially those involving hazardous production materials. To help guide the researcher through the vast list of requirements, the EHS office at NREL has taken a variety of steps. Organizationally, the office has developed hazard-specific laboratory-level procedures to govern particular activities. These procedures are a distillation of appropriate international codes, fire agencies, SEMI standards, U.S. Department of Energy orders, and other industry standards to those necessary and sufficient to govern the safe operation of a given activity. The EHS office works proactively with researchers after a concept for a new R&D capability is conceived to help guide the safe design, acquisition, installation, and operation of the equipment. It starts with a safety assessment at the early stages such that requirements are implemented to determine the level of risk and degree of complexity presented by the activity so appropriate controls can be put in place to manage the risk. As the equipment requirements and design are refined, appropriate equipment standards are applied. Before the 'to-build' specifications are finalized, a process hazard analysis is performed to ensure that no single-point failure presents an unacceptable risk. Finally, as the tool goes through construction and installation stages, reviews are performed at logical times to ensure that the requisite engineering controls and design are in place and operational. Authorization to

  15. Change in the structures, dynamics and disease-related mortality rates of the population of Qatari nationals: 2007-2011.

    Science.gov (United States)

    Al-Thani, Mohamed H; Sadoun, Eman; Al-Thani, Al-Anoud; Khalifa, Shamseldin A; Sayegh, Suzan; Badawi, Alaa

    2014-12-01

    Developing effective public health policies and strategies for interventions necessitates an assessment of the structure, dynamics, disease rates and causes of death in a population. Lately, Qatar has undertaken development resurgence in health and economy that resulted in improving the standard of health services and health status of the entire Qatari population (i.e., Qatari nationals and non-Qatari residents). No study has attempted to evaluate the population structure/dynamics and recent changes in disease-related mortality rates among Qatari nationals. The present study examines the population structure/dynamics and the related changes in the cause-specific mortality rates and disease prevalence in the Qatari nationals. This is a retrospective, analytic descriptive analysis covering a period of 5years (2007-2011) and utilizes a range of data sources from the State of Qatar including the population structure, disease-related mortality rates, and the prevalence of a range of chronic and infectious diseases. Factors reflecting population dynamics such as crude death (CDR), crude birth (CBR), total fertility (TFR) and infant mortality (IMR) rates were also calculated. The Qatari nationals is an expansive population with an annual growth rate of ∼4% and a stable male:female ratio. The CDR declined by 15% within the study period, whereas the CBR was almost stable. The total disease-specific death rate, however, was decreased among the Qatari nationals by 23% due to the decline in mortality rates attributed to diseases of the blood and immune system (43%), nervous system (44%) and cardiovascular system (41%). There was a high prevalence of a range of chronic diseases, whereas very low frequencies of the infectious diseases within the study population. Public health strategies, approaches and programs developed to reduce disease burden and the related death, should be tailored to target the population of Qatari nationals which exhibits characteristics that vary from

  16. Earth Science and Public Health: Proceedings of the Second National Conference on USGS Health-Related Research

    Science.gov (United States)

    Buxton, Herbert T.; Griffin, Dale W.; Pierce, Brenda S.

    2007-01-01

    The mission of the U.S. Geological Survey (USGS) is to serve the Nation by providing reliable scientific information to describe and understand the earth; minimize loss of life and property from natural disasters; manage water, biological, energy, and mineral resources; and enhance and protect our quality of life. As the Nation?s largest water, earth, and biological science and civilian mapping agency, the USGS can play a significant role in providing scientific knowledge and information that will improve our understanding of the relations of environment and wildlife to human health and disease. USGS human health-related research is unique in the Federal government because it brings together a broad spectrum of natural science expertise and information, including extensive data collection and monitoring on varied landscapes and ecosystems across the Nation. USGS can provide a great service to the public health community by synthesizing the scientific information and knowledge on our natural and living resources that influence human health, and by bringing this science to the public health community in a manner that is most useful. Partnerships with health scientists and managers are essential to the success of these efforts. USGS scientists already are working closely with the public health community to pursue rigorous inquiries into the connections between natural science and public health. Partnering agencies include the Armed Forces Institute of Pathology, Agency for Toxic Substances Disease Registry, Centers for Disease Control and Prevention, U.S. Environmental Protection Agency, Food and Drug Administration, Mine Safety and Health Administration, National Cancer Institute, National Institute of Allergy and Infectious Disease, National Institute of Environmental Health Sciences, National Institute for Occupational Safety and Health, U.S. Public Health Service, and the U.S. Army Medical Research Institute of Infectious Diseases. Collaborations between public

  17. [Issues related to national university medical schools: focusing on the low wages of university hospital physicians].

    Science.gov (United States)

    Takamuku, Masatoshi

    2015-01-01

    University hospitals, bringing together the three divisions of education, research, and clinical medicine, could be said to represent the pinnacle of medicine. However, when compared with physicians working at public and private hospitals, physicians working at university hospitals and medical schools face extremely poor conditions. This is because physicians at national university hospitals are considered to be "educators." Meanwhile, even after the privatization of national hospitals, physicians working for these institutions continue to be perceived as "medical practitioners." A situation may arise in which physicians working at university hospitals-performing top-level medical work while also being involved with university and postgraduate education, as well as research-might leave their posts because they are unable to live on their current salaries, especially in comparison with physicians working at national hospitals, who focus solely on medical care. This situation would be a great loss for Japan. This potential loss can be prevented by amending the classification of physicians at national university hospitals from "educators" to "medical practitioners." In order to accomplish this, the Japan Medical Association, upon increasing its membership and achieving growth, should act as a mediator in negotiations between national university hospitals, medical schools, and the government.

  18. Hypertension and hypertension-related disease in Mongolia; findings of a national knowledge, attitudes and practices study

    DEFF Research Database (Denmark)

    Demaio, Alessandro R; Otgontuya, Dugee; de Courten, Maximilian

    2013-01-01

    Mongolia has a high and increasing burden of hypertension and related disease, with cardiovascular diseases among the leading causes of death. Yet little is known about the knowledge, attitudes and practices of the Mongolian population with regards to blood pressure. With this in mind, a national...

  19. Self-Rated Health in Relation to Rape and Mental Health Disorders in a National Sample of College Women

    Science.gov (United States)

    Zinzow, Heidi M.; Amstadter, Ananda B.; McCauley, Jenna L.; Ruggiero, Kenneth J.; Resnick, Heidi S.; Kilpatrick, Dean G.

    2011-01-01

    Objective: The purpose of this study was to employ a multivariate approach to examine the correlates of self-rated health in a college sample of women, with particular emphasis on sexual assault history and related mental health outcomes. Participants: A national sample of 2,000 female college students participated in a structured phone interview…

  20. Rehabilitation-Related Research on Disability and Employer Practices Using Individual-Based National and Administrative Data Sets

    Science.gov (United States)

    Nazarov, Zafar E.; Erickson, William A.; Bruyère, Susanne M.

    2014-01-01

    Objective: It is useful to examine workplace factors influencing employment outcomes of individuals with disabilities and the interplay of disability, employment-related, and employer characteristics to inform rehabilitation practice. Design: A number of large national survey and administrative data sets provide information on employers and can…

  1. Dietary Habits and Supplement Use in Relation to National Pregnancy Recommendations: Data from the EuroPrevall Birth Cohort

    NARCIS (Netherlands)

    Oliver, E. M.; Grimshaw, K. E. C.; Schoemaker, A. A.; Keil, T.; McBride, D.; Sprikkelman, A. B.; Ragnarsdottir, H. S.; Trendelenburg, V.; Emmanouil, E.; Reche, M.; Fiocchi, A.; Fiandor, A.; Stanczyk-Przyluska, A.; Wilczynski, J.; Busacca, M.; Sigurdardottir, S. T.; Dubakiene, R.; Rudzeviciene, O.; Vlaxos, G. D.; Beyer, K.; Roberts, G.

    2014-01-01

    Assessing maternal dietary habits across Europe during pregnancy in relation to their national pregnancy recommendations. A collaborative, multi-centre, birth cohort study in nine European countries was conducted as part of European Union funded EuroPrevall project. Standardised baseline

  2. Relative validity of the pre-coded food diary used in the Danish National Survey of Diet and Physical Activity

    DEFF Research Database (Denmark)

    Knudsen, Vibeke Kildegaard; Gille, Maj-Britt; Nielsen, Trine Holmgaard

    2011-01-01

    Objective: To determine the relative validity of the pre-coded food diary applied in the Danish National Survey of Dietary Habits and Physical Activity. Design: A cross-over study among seventy-two adults (aged 20 to 69 years) recording diet by means of a pre-coded food diary over 4 d and a 4 d...

  3. External costs related to power production technologies. ExternE national implementation for Denmark

    International Nuclear Information System (INIS)

    Schleisner, L.; Sieverts Nielsen, P.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results; to aggregate these site- and technology-specific results to more general figures. The current report covers the results of the national implementation for Denmark. Three different fuel cycles have been chosen as case studies. These are fuel cycles for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant based on biogas. The report covers all the details of the application of the methodology to these fuel cycles aggregation to a national level. (au) EU-JOULE 3. 59 tabs., 25 ills., 61 refs

  4. External costs related to power production technologies. ExternE national implementation for Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Schleisner, L; Sieverts Nielsen, P

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results; to aggregate these site- and technology-specific results to more general figures. The current report covers the results of the national implementation for Denmark. Three different fuel cycles have been chosen as case studies. These are fuel cycles for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant based on biogas. The report covers all the details of the application of the methodology to these fuel cycles aggregation to a national level. (au) EU-JOULE 3. 59 tabs., 25 ills., 61 refs.

  5. Effectiveness of Chain Link Turtle Fence and Culverts in Reducing Turtle Mortality and Providing Connectivity along U.S. Hwy 83, Valentine National Wildlife Refuge, Nebraska, USA

    Science.gov (United States)

    2017-12-01

    We evaluated the effectiveness of existing turtle fences through collecting and analyzing turtle mortality data along U.S. Hwy 83, in and around Valentine National Wildlife Refuge, Nebraska, USA. We also investigated the level of connectivity for tur...

  6. 76 FR 47594 - National Institutes of Health; Proposed Collection; Comment Request; Simulations for Drug Related...

    Science.gov (United States)

    2011-08-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES [Billing Code 4140-01-P] National Institutes of Health... request for a one-time clearance to evaluate an interactive multimedia module developed by ArchieMD. This evaluation seeks to determine whether the multimedia module Archie MD: The Science of Drugs (1) Increases...

  7. 78 FR 68470 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-11-14

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-WASO-NRNHL-14338; PPWOCRADI0, PCU00RP14... County House at 1111 North Los Robles Avenue, (Residential Architecture of Pasadena: Influence of the... Robles Avenue, (Residential Architecture of Pasadena: Influence of the Arts and Crafts Movement MPS) 1121...

  8. 76 FR 50494 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-08-15

    ... comments should be submitted by August 30, 2011. Before including your address, phone number, e-mail... Historic Places/National Historic Landmarks Program. COLORADO Huerfano County Veta Pass, 3652, 3665, 3688 Cty. Rd. 443, La Veta, 11000607 Pueblo County Pueblo Christopher Columbus Monument, Median in 100 Blk...

  9. 75 FR 14181 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-03-24

    ... public review, we cannot guarantee that we will be able to do so. J. Paul Loether, Chief, National... Parkway System 1817-1959) 5083 Colerain Ave., Cincinnati, 10000191 Hocking County Logan Historic District, Roughly Bounded by Second St., Spring St., Hill St., Keynes Dr. & Culver St., Logan, 10000192 Miami County...

  10. 76 FR 52968 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-08-24

    ... Clarke County Cleridge, 1649 Old Charles Town Rd., Stephenson, 11000653 In the interest of preservation.../National Historic Landmarks Program. ARIZONA Maricopa County el chaparral, 4935 E. Lafayette Blvd., Phoenix, 11000631 COLORADO Park County Threemile Gulch, Address Restricted, Hartsel, 11000632 MAINE Knox County Land...

  11. 77 FR 74511 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-12-14

    ... of Historic Places/National Historic Landmarks Program. ALABAMA Morgan County East Old Town Historic District, Address Restricted, Decatur, 12001079 West Old Town Historic District, Address Restricted, Decatur, 12001080 COLORADO Routt County Bell and Canant Mercantile--Crossan's M and A Market, 101 Main St...

  12. 76 FR 22142 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-04-20

    .../National Historic Landmarks Program. ARKANSAS Cleburne County Old Highway 16 Bridge, Lakefront Resort Rd., Edgemont, 11000262 GEORGIA Coweta County Vinewood, 1324 Roscoe Rd., Newnan, 11000263 Troup County Westside... Syracuse MPS), 223 DeWitt St., Syracuse, 11000277 Sullivan County Forestburgh Town Hall, 305 Cty Rd. 48...

  13. 78 FR 26391 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-05-06

    ... Architecture MPS), 100 Casey Key Rd., Nokomis, 13000320 MICHIGAN Genesee County United States Post Office, 600 Church St., Flint, 13000321 Wayne County United States Immigration Station, 333 Mount Elliott St... properties under the National Register criteria for evaluation. Comments may be forwarded by United States...

  14. 76 FR 17670 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-03-30

    ... Canyon, Globe, 11000205 Maricopa County Eisendrath, Rose, House, 1400 N College Ave, Tempe, 11000206... Bomber), Lake Mead National Recreation Area, Overton, 11000212 NORTH CAROLINA Guilford County Model Farm... Office Building, 300 E 8th St, Austin, 11000211 WISCONSIN Winnebago County Whiting, Frank, Boathouse, 98...

  15. Glacier-related landforms and glacial lakes in Huascarán National Park, Peru

    Czech Academy of Sciences Publication Activity Database

    Vilímek, V.; Klimeš, Jan; Červená, L.

    2016-01-01

    Roč. 12, č. 1 (2016), s. 193-202 ISSN 1744-5647 R&D Projects: GA ČR(CZ) GAP209/11/1000 Institutional support: RVO:67985891 Keywords : moraines * rock glaciers * glacial lakes * Cordillera Blanca * Huascarán National Park * Peru Subject RIV: DE - Earth Magnetism, Geodesy, Geography Impact factor: 2.174, year: 2016

  16. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the Link - Drugs and HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors ... GA: CDC, DHHS. Retrieved November 2017. How are Drug Misuse and HIV Related? Drug misuse and addiction ...

  17. Research strategies and programs related to the National Plan of Management of Radioactive Materials and Wastes. Issue 2008

    International Nuclear Information System (INIS)

    2008-01-01

    After having recalled the legal context defining the requirements of the PNGMDR (Plan national de gestion des matieres et dechets radioactifs, national plan of management of radioactive materials and wastes), this report presents several research programs which address various domains: waste packaging and behaviour (decontamination, waste characterization, waste processing, the storage sizing inventory model, parcel behaviour, used fuel evolution, future wastes), warehousing and storage in deep geological formation (characterization of the Meuse/Haute-Marne site, scientific program, simulation programs, measurement means for storage monitoring, knowledge base, security and reversibility options for storage design, security studies, warehousing options), storage of radiferous and graphite wastes, investigation of separation/transmutation scenarios, investigations related to separation, investigations related to fuel fabrication, investigations related to the transmutation of minor actinides, researches in social and human sciences

  18. The national and subnational prevalence and burden of age-related macular degeneration in China.

    Science.gov (United States)

    Song, Peige; Du, Yuhang; Chan, Kit Yee; Theodoratou, Evropi; Rudan, Igor

    2017-12-01

    Age-related macular degeneration (AMD) is the third most common cause of blindness, and the fourth leading cause of visual impairment worldwide, but little is known about the burden of this disease in the most populous country-China. This study provides the first comprehensive estimates of the prevalence and burden of AMD in China from 1990 to 2015, with projections till 2050. In this study, a systematic review and meta-analysis was conducted to estimate the prevalence of AMD in China. China National Knowledge Infrastructure (CNKI), Wanfang, Chinese Biomedicine Literature Database (CBM-SinoMed), PubMed, Embase and Medline were searched before September 2016. Multilevel mixed-effect meta-regression was performed to define the prevalence rates of AMD and its subtypes. UN population data were used to estimate and project the number of people affected from 1990 to 2050. Based on different demographic and geographic features, the national burden of AMD in 2000 and 2010 was distributed to different regions in China. Our search returned 2016 citations, of which 25 met the inclusion criteria. The prevalence of any AMD ranged from 2.44% (95% CI = 1.85-3.22) in people aged 45-49 years to 18.98% (95% CI = 15.05-23.66) in people aged 85-89 years. Prevalence of early AMD ranged from 1.79% (95% CI = 1.05-3.02) to 10.05% (95% CI = 6.17-15.97), and, in the case of late AMD, from 0.38% (95% CI = 0.16-0.97) to 3.88% (95% CI = 1.68-9.13). In late AMD, the prevalence of geographic atrophy (GA) was 0.15% (95% CI = 0.05-0.47) in people aged 45-49 years and 1.09% (95% CI = 0.35-3.36) in those aged 85-89 years, and the prevalence of neovascular AMD (NVAMD) ranged between 0.24% (95% CI = 0.11-0.50) and 2.79% (95% CI = 1.33-5.77). The number of people with any AMD was 12.01 million (95% CI = 9.29-15.46) in 1990 and 26.65 million (95% CI = 20.62-34.27) in 2015. Within the same period, the number of people with early AMD increased from 9

  19. MULTI-CORE AND OPTICAL PROCESSOR RELATED APPLICATIONS RESEARCH AT OAK RIDGE NATIONAL LABORATORY

    Energy Technology Data Exchange (ETDEWEB)

    Barhen, Jacob [ORNL; Kerekes, Ryan A [ORNL; ST Charles, Jesse Lee [ORNL; Buckner, Mark A [ORNL

    2008-01-01

    High-speed parallelization of common tasks holds great promise as a low-risk approach to achieving the significant increases in signal processing and computational performance required for next generation innovations in reconfigurable radio systems. Researchers at the Oak Ridge National Laboratory have been working on exploiting the parallelization offered by this emerging technology and applying it to a variety of problems. This paper will highlight recent experience with four different parallel processors applied to signal processing tasks that are directly relevant to signal processing required for SDR/CR waveforms. The first is the EnLight Optical Core Processor applied to matched filter (MF) correlation processing via fast Fourier transform (FFT) of broadband Dopplersensitive waveforms (DSW) using active sonar arrays for target tracking. The second is the IBM CELL Broadband Engine applied to 2-D discrete Fourier transform (DFT) kernel for image processing and frequency domain processing. And the third is the NVIDIA graphical processor applied to document feature clustering. EnLight Optical Core Processor. Optical processing is inherently capable of high-parallelism that can be translated to very high performance, low power dissipation computing. The EnLight 256 is a small form factor signal processing chip (5x5 cm2) with a digital optical core that is being developed by an Israeli startup company. As part of its evaluation of foreign technology, ORNL's Center for Engineering Science Advanced Research (CESAR) had access to a precursor EnLight 64 Alpha hardware for a preliminary assessment of capabilities in terms of large Fourier transforms for matched filter banks and on applications related to Doppler-sensitive waveforms. This processor is optimized for array operations, which it performs in fixed-point arithmetic at the rate of 16 TeraOPS at 8-bit precision. This is approximately 1000 times faster than the fastest DSP available today. The optical core

  20. MULTI-CORE AND OPTICAL PROCESSOR RELATED APPLICATIONS RESEARCH AT OAK RIDGE NATIONAL LABORATORY

    International Nuclear Information System (INIS)

    Barhen, Jacob; Kerekes, Ryan A.; St Charles, Jesse Lee; Buckner, Mark A.

    2008-01-01

    High-speed parallelization of common tasks holds great promise as a low-risk approach to achieving the significant increases in signal processing and computational performance required for next generation innovations in reconfigurable radio systems. Researchers at the Oak Ridge National Laboratory have been working on exploiting the parallelization offered by this emerging technology and applying it to a variety of problems. This paper will highlight recent experience with four different parallel processors applied to signal processing tasks that are directly relevant to signal processing required for SDR/CR waveforms. The first is the EnLight Optical Core Processor applied to matched filter (MF) correlation processing via fast Fourier transform (FFT) of broadband Dopplersensitive waveforms (DSW) using active sonar arrays for target tracking. The second is the IBM CELL Broadband Engine applied to 2-D discrete Fourier transform (DFT) kernel for image processing and frequency domain processing. And the third is the NVIDIA graphical processor applied to document feature clustering. EnLight Optical Core Processor. Optical processing is inherently capable of high-parallelism that can be translated to very high performance, low power dissipation computing. The EnLight 256 is a small form factor signal processing chip (5x5 cm2) with a digital optical core that is being developed by an Israeli startup company. As part of its evaluation of foreign technology, ORNL's Center for Engineering Science Advanced Research (CESAR) had access to a precursor EnLight 64 Alpha hardware for a preliminary assessment of capabilities in terms of large Fourier transforms for matched filter banks and on applications related to Doppler-sensitive waveforms. This processor is optimized for array operations, which it performs in fixed-point arithmetic at the rate of 16 TeraOPS at 8-bit precision. This is approximately 1000 times faster than the fastest DSP available today. The optical core

  1. The Effect of individual Difference on Perceptions of Job-related Stress among National College and University Librarians in Taiwan

    Directory of Open Access Journals (Sweden)

    Su-may Sheih Chen

    2004-06-01

    Full Text Available Defined as an environmental force in the workplace, either real or imagined, job-related stress interacts with an individual’s perception. Individuals’ perceptions alter with age, gender, work experience, job characteristics, and personality behavior of individuals. In an attempt to gain a comprehensive understanding, this study examines the relationship between individual difference and the perceptions of job-related stress in the library settings of national colleges and universities on Taiwan. The result shows that individual difference is influential for librarians’ perceptions of job-related stress. [Article content in Chinese

  2. Trail impacts and trail impact management related to ecotourism visitation at Torres del Paine National Park, Chile

    Science.gov (United States)

    Farrell, T.A.; Marion, J.L.

    2002-01-01

    Ecotourism and protected area visitation in Central and South America are largely dependent upon a relatively undisturbed quality of natural resources. However, visitation may impact vegetation, soil, water and wildlife resources, and degrade visitor facilities such as recreation sites and trails. Findings are reported from trail impact research conducted at Torres del Paine National Park in Patagonia, Chile. The frequency and magnitude of selected trail impacts and the relative effect of the amount of use, vegetation type, trail position and trail grade are investigated. Findings differed from previous studies in that amount of use was significantly related to both trail width increases and trail erosion. Management actions to minimize trail impacts are offered.

  3. N.3201 National Assembly law project relative to the energy sector

    International Nuclear Information System (INIS)

    2006-01-01

    This law text, elaborated in the framework of the energy market deregulation, presents the market deregulation and the free choice for the consumers, the dispositions relative to the gas and electric power distribution, the dispositions relative to the Gaz de France capital and the State control and dispositions relatives to contracts of natural ags and electric power supply. (A.L.B.)

  4. Evaluation of national health-care related infection criteria for epidemiological surveillance in neonatology.

    Science.gov (United States)

    Ferreira, Janita; Bouzada, Maria C F; Jesus, Lenize A de; Cortes, Maria da Conceição Werneck; Armond, Guilherme A; Clemente, Wanessa T; Anchieta, Lêni M; Romanelli, Roberta M C

    2014-01-01

    to assess the use of the Brazilian criteria for reporting of hospital-acquired infections (HAIs) in the neonatal unit and compare them with the criteria proposed by the National Healthcare Safety Network (NHSN). this was a cross-sectional study conducted from 2009 to 2011. It included neonates with HAI reporting by at least one of the criteria. Statistical analysis included calculation of incidence density of HAIs, distribution by weight, and by reporting criterion. Analysis of sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for the national criteria was performed considering the NHSN as the gold standard, with agreement assessed by kappa. a total of 882 newborns were followed, and 330 had at least one infection notified by at least one of the criteria. A total of 522 HAIs were reported, regardless of the criteria. An incidence density of 27.28 infections per 1,000 patient-days was observed, and the main topographies were sepsis (58.3%), candidiasis (15.1%), and conjunctivitis (6.5%). A total of 489 (93.7%) were notified by both criteria, eight infections were notified only by the national criteria (six cases of necrotizing enterocolitis and two cases of conjunctivitis), and 25 cases of clinical sepsis were reported by NHSN criteria only. The sensitivity, specificity, PPV, and NPV were 95.1%, 98.6%, 98.4%, and 95.7%, respectively, for all topographies, and were 91.8%, 100%, 100%, and 96.3% for the analysis of sepsis. Kappa analysis showed an agreement of 96.9%. there was a high rate of agreement between the criteria. The use of the national criteria facilitates the reporting of sepsis in newborns, and can help to improve the specificity and PPV. Copyright © 2014 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  5. National evaluation commission relative to the researches on the radioactive wastes management

    International Nuclear Information System (INIS)

    2004-01-01

    Implemented in april 1994, the National Evaluation Commission (CNE) continues in this tenth report, its study on the radioactive wastes management following the three axis defined by the 1991 law: separation and transmutation, underground disposal, conditioning and log time storage. This report takes stock on the CNE activity in 2003 as on the researches advances around these three axis. In the framework of the international cooperation, the commission details also the researches and realizations abroad. (A.L.B.)

  6. Identification of gaps in the national research effort related to radioactive waste management

    International Nuclear Information System (INIS)

    Thorne, M.C.; Plews, M.; Kane, P.

    1987-08-01

    Based on papers submitted to the Government's Radioactivity Research and Environmental Monitoring Committee (RadREM), this report presents a consolidated summary of perceived research requirements for 1988/89 and a comparison with the research proposed for that period. On this basis, discussion is included of gaps in the national research effort to 1989, duplication of research plans and areas where better co-ordination or funding of research might be appropriate. (author)

  7. United Nations Peacekeeping Participation and Civil-Military Relations in Troop Contributing Countries

    Science.gov (United States)

    2010-03-01

    required the NA to be more inclusive, incorporating specified percentages of women and Madheshi, Dalit , Janjati and other ethnic groups.92 The Maoists...character, the entry of citizens, including Madhesis, indigenous nationalities, Dalits , women and those from marginalized areas, shall be ensured...as India . The thesis also relies on the literature on peacekeeping and CMR. It is widely believed that participation in peacekeeping operations

  8. Evaluation of national health-care related infection criteria for epidemiological surveillance in neonatology

    Directory of Open Access Journals (Sweden)

    Janita Ferreira

    2014-07-01

    Full Text Available OBJECTIVE: to assess the use of the Brazilian criteria for reporting of hospital-acquired infections (HAIs in the neonatal unit and compare them with the criteria proposed by the National Healthcare Safety Network (NHSN. METHODS: this was a cross-sectional study conducted from 2009 to 2011. It included neonates with HAI reporting by at least one of the criteria. Statistical analysis included calculation of incidence density of HAIs, distribution by weight, and by reporting criterion. Analysis of sensitivity, specificity, positive predictive value (PPV, and negative predictive value (NPV for the national criteria was performed considering the NHSN as the gold standard, with agreement assessed by kappa. RESULTS: a total of 882 newborns were followed, and 330 had at least one infection notified by at least one of the criteria. A total of 522 HAIs were reported, regardless of the criteria. An incidence density of 27.28 infections per 1,000 patient-days was observed, and the main topographies were sepsis (58.3%, candidiasis (15.1%, and conjunctivitis (6.5%. A total of 489 (93.7% were notified by both criteria, eight infections were notified only by the national criteria (six cases of necrotizing enterocolitis and two cases of conjunctivitis, and 25 cases of clinical sepsis were reported by NHSN criteria only. The sensitivity, specificity, PPV, and NPV were 95.1%, 98.6%, 98.4%, and 95.7%, respectively, for all topographies, and were 91.8%, 100%, 100%, and 96.3% for the analysis of sepsis. Kappa analysis showed an agreement of 96.9%. CONCLUSION: there was a high rate of agreement between the criteria. The use of the national criteria facilitates the reporting of sepsis in newborns, and can help to improve the specificity and PPV.

  9. Development of national standards related to the integrated safety and security of high-rise buildings

    Science.gov (United States)

    Voskresenskaya, Elena; Vorona-Slivinskaya, Lubov

    2018-03-01

    The article considers the issues of developing national standards for high-rise construction. The system of standards should provide industrial, operational, economic and terrorist safety of high-rise buildings and facilities. Modern standards of high-rise construction should set the rules for designing engineering systems of high-rise buildings, which will ensure the integrated security of buildings, increase their energy efficiency and reduce the consumption of resources in construction and operation.

  10. Contributions of national and global health estimates to monitoring health-related sustainable development goals.

    Science.gov (United States)

    Bundhamcharoen, Kanitta; Limwattananon, Supon; Kusreesakul, Khanitta; Tangcharoensathien, Viroj

    2016-01-01

    The millennium development goals triggered an increased demand for data on child and maternal mortalities for monitoring progress. With the advent of the sustainable development goals and growing evidence of an epidemiological transition toward non-communicable diseases, policymakers need data on mortality and disease trends and distribution to inform effective policies and support monitoring progress. Where there are limited capacities to produce national health estimates (NHEs), global health estimates (GHEs) can fill gaps for global monitoring and comparisons. This paper discusses lessons learned from Thailand's burden of disease (BOD) study on capacity development on NHEs and discusses the contributions and limitations of GHEs in informing policies at the country level. Through training and technical support by external partners, capacities are gradually strengthened and institutionalized to enable regular updates of BOD at national and subnational levels. Initially, the quality of cause-of-death reporting in death certificates was inadequate, especially for deaths occurring in the community. Verbal autopsies were conducted, using domestic resources, to determine probable causes of deaths occurring in the community. This method helped to improve the estimation of years of life lost. Since the achievement of universal health coverage in 2002, the quality of clinical data on morbidities has also considerably improved. There are significant discrepancies between the Global Burden of Disease 2010 study estimates for Thailand and the 1999 nationally generated BOD, especially for years of life lost due to HIV/AIDS, and the ranking of priority diseases. National ownership of NHEs and an effective interface between researchers and decision-makers contribute to enhanced country policy responses, whereas subnational data are intended to be used by various subnational partners. Although GHEs contribute to benchmarking country achievement compared with global health

  11. Development of national standards related to the integrated safety and security of high-rise buildings

    Directory of Open Access Journals (Sweden)

    Voskresenskaya Elena

    2018-01-01

    Full Text Available The article considers the issues of developing national standards for high-rise construction. The system of standards should provide industrial, operational, economic and terrorist safety of high-rise buildings and facilities. Modern standards of high-rise construction should set the rules for designing engineering systems of high-rise buildings, which will ensure the integrated security of buildings, increase their energy efficiency and reduce the consumption of resources in construction and operation.

  12. Environmental assessment related to the operation of Argonne National Laboratory, Argonne, Illinois

    Energy Technology Data Exchange (ETDEWEB)

    1982-08-01

    In order to evaluate the environmental impacts of Argonne National Laboratory (ANL) operations, this assessment includes a descriptive section which is intended to provide sufficient detail to allow the various impacts to be viewed in proper perspective. In particular, details are provided on site characteristics, current programs, characterization of the existing site environment, and in-place environmental monitoring programs. In addition, specific facilities and operations that could conceivably impact the environment are described at length. 77 refs., 16 figs., 47 tabs.

  13. Cultural Connectedness and Its Relation to Mental Wellness for First Nations Youth.

    Science.gov (United States)

    Snowshoe, Angela; Crooks, Claire V; Tremblay, Paul F; Hinson, Riley E

    2017-04-01

    We explored the interrelationships among components of cultural connectedness (i.e., identity, traditions, and spirituality) and First Nations youth mental health using a brief version of the original Cultural Connectedness Scale. Participants included 290 First Nations youth (M age  = 14.4) who were recruited from both urban and rural school settings in Saskatchewan and Southwestern Ontario. We performed a confirmatory factor analysis of the Cultural Connectedness Scale-Short Version (CCS-S) items to investigate the factor stability of the construct in our sample. We examined the relationships between the CCS-S subscales and self-efficacy, sense of self (present and future), school connectedness, and life satisfaction using hierarchical multiple linear regression analyses to establish the validity of the abbreviated measure. The results revealed that cultural connectedness, as measured by the 10-item CCS-S, had strong associations with the mental health indicators assessed and, in some cases, was associated with First Nations youth mental health above and beyond other social determinants of health. Our results extend findings from previous research on cultural connectedness by elucidating the meaning of its components and demonstrate the importance of culture for positive youth development.

  14. Between Jewish settlers and Palestinian citizens of Israel: negotiating ethno-national power relations through the discourse of PTSD.

    Science.gov (United States)

    Friedman-Peleg, Keren

    2014-12-01

    This article traces a critical change in the professional implementation of posttraumatic stress disorder (PTSD): the broadening of its use from an apolitical sign of psychopathology, to an interpretative framework in which clinical questions of diagnosis and treatment intersect with political questions of ethno-national power relations. The aid discourse of a new NGO--the "Israeli Trauma Coalition" (ITC)--serves as my case study. I analyze how the experts negotiated similar clinical questions, associated with a single biomedical idiom, PTSD, but in relation to two different matrices of political relations: the "Disengagement Plan" (August 2005), which led to the evacuation of National-Orthodox Jews who had settled in the Occupied Territories, and the Second Lebanon War (July 2006), which led to the exposure of Palestinian citizens of Israel to missile attacks. In particular, I shed light on the ITC's decision-making processes regarding the organizational representation of suffering and its empirical validation. I found that the distress of both groups has been left dangling between the processes of medicalization and de-medicalization, while a context-related transition from one meaning of trauma to another has taken place. Finally, I discuss how this implementation of PTSD compares with other national sites of its growing globalization.

  15. Guide on a national system for collecting, assessing and disseminating information on safety-related events in nuclear power plants

    International Nuclear Information System (INIS)

    1983-02-01

    There is a wide spectrum of safety significance in the events that can occur during nuclear power plant operations. It is important that lessons be learned from safety-related events (hereinafter referred to as unusual events) so as to improve the safety of nuclear power plants. Hence formal procedures should be established for this purpose. The purpose of this document is to provide guidance to Member States for establishing a system (hereinafter referred to as a national system) for collecting, storing, retrieving, assessing and disseminating information on unusual events in nuclear power plants. The guidance given is based on experience gained in the use of existing national and international systems. This guide covers a national system that is part of a programme to improve nuclear power plant safety using experience gained from operating plants both within and outside the country. Implementing the recommendations in this guide would render any national system compatible with other national systems and facilitate the participation in the IAEA System for Reporting Unusual Events with Safety Significance (hereinafter referred to as the IAEA Incident Reporting System, IAEA-IRS) for more widespread dissemination of lessons learned from nuclear power plant operation

  16. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Notes Podcasts E-Newsletters Public Education Projects National Drug & Alcohol Facts Week NIDA TV PEERx Drugs & Health Blog ... Award for Addiction Science USA Science & Engineering Festival Drug & Alcohol Chat Day HBO Addiction Project Learn the Link ...

  17. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Process Funding Priorities Research Training News & Events News Nora's Blog NIDA in the News NIDA Notes Podcasts ... of the National Institute on Drug Abuse, Dr. Nora D. Volkow. Message from the Director The Link ...

  18. Linking Recognition Practices and National Qualifications Frameworks: International Benchmarking of Experiences and Strategies on the Recognition, Validation and Accreditation (RVA) of Non-Formal and Informal Learning

    Science.gov (United States)

    Singh, Madhu, Ed.; Duvekot, Ruud, Ed.

    2013-01-01

    This publication is the outcome of the international conference organized by UNESCO Institute for Lifelong Learning (UIL), in collaboration with the Centre for Validation of Prior Learning at Inholland University of Applied Sciences, the Netherlands, and in partnership with the French National Commission for UNESCO that was held in Hamburg in…

  19. A workplace email-linked website intervention for modifying cancer-related dietary and lifestyle risk factors: rationale, design and baseline findings.

    Science.gov (United States)

    Ang, Y K; Mirnalini, K; Zalilah, M S

    2013-04-01

    The use of email and website as channels for workplace health information delivery is not fully explored. This study aims to describe the rationale, design, and baseline findings of an email-linked website intervention to improve modifiable cancer risk factors. Employees of a Malaysian public university were recruited by systematic random sampling and randomised into an intervention (n = 174) or control group (n = 165). A website was developed for the intervention and educational modules were uploaded onto the website. The intervention group received ten consecutive weekly emails with hypertext links to the website for downloading the modules and two individual phone calls as motivational support whilst the control group received none. Diet, lifestyle, anthropometric measurements, psychosocial factors and stages of change related to dietary fat, fruit and vegetable intake, and physical activity were assessed. Participants were predominantly female and in non-academic positions. Obesity was prevalent in 15% and 37% were at risk of co-morbidities. Mean intake of fats was 31%, fruit was -1 serving/day and vegetable was < 1 serving/day. Less than 20% smoked and drank alcohol and about 40% were physically inactive. The majority of the participants fell into the Preparation stage for decreasing fat intake, eating more fruit and vegetables, and increasing physical activity. Self-efficacy and perceived benefits were lowest among participants in the Precontemplation/Contemplation stage compared to the Preparation and Action/Maintenance stages. Baseline data show that dietary and lifestyle practices among the employees did not meet the international guidelines for cancer prevention. Hence the findings warrant the intervention planned.

  20. Privacy preserving probabilistic record linkage (P3RL): a novel method for linking existing health-related data and maintaining participant confidentiality.

    Science.gov (United States)

    Schmidlin, Kurt; Clough-Gorr, Kerri M; Spoerri, Adrian

    2015-05-30

    Record linkage of existing individual health care data is an efficient way to answer important epidemiological research questions. Reuse of individual health-related data faces several problems: Either a unique personal identifier, like social security number, is not available or non-unique person identifiable information, like names, are privacy protected and cannot be accessed. A solution to protect privacy in probabilistic record linkages is to encrypt these sensitive information. Unfortunately, encrypted hash codes of two names differ completely if the plain names differ only by a single character. Therefore, standard encryption methods cannot be applied. To overcome these challenges, we developed the Privacy Preserving Probabilistic Record Linkage (P3RL) method. In this Privacy Preserving Probabilistic Record Linkage method we apply a three-party protocol, with two sites collecting individual data and an independent trusted linkage center as the third partner. Our method consists of three main steps: pre-processing, encryption and probabilistic record linkage. Data pre-processing and encryption are done at the sites by local personnel. To guarantee similar quality and format of variables and identical encryption procedure at each site, the linkage center generates semi-automated pre-processing and encryption templates. To retrieve information (i.e. data structure) for the creation of templates without ever accessing plain person identifiable information, we introduced a novel method of data masking. Sensitive string variables are encrypted using Bloom filters, which enables calculation of similarity coefficients. For date variables, we developed special encryption procedures to handle the most common date errors. The linkage center performs probabilistic record linkage with encrypted person identifiable information and plain non-sensitive variables. In this paper we describe step by step how to link existing health-related data using encryption methods to

  1. Identification of sequence-related amplified polymorphism markers linked to the red leaf trait in ornamental kale (Brassica oleracea L. var. acephala).

    Science.gov (United States)

    Wang, Y S; Liu, Z Y; Li, Y F; Zhang, Y; Yang, X F; Feng, H

    2013-04-02

    Artistic diversiform leaf color is an important agronomic trait that affects the market value of ornamental kale. In the present study, genetic analysis showed that a single-dominant gene, Re (red leaf), determines the red leaf trait in ornamental kale. An F2 population consisting of 500 individuals from the cross of a red leaf double-haploid line 'D05' with a white leaf double-haploid line 'D10' was analyzed for the red leaf trait. By combining bulked segregant analysis and sequence-related amplified polymorphism technology, we identified 3 markers linked to the Re/re locus. A genetic map of the Re locus was constructed using these sequence-related amplified polymorphism markers. Two of the markers, Me8Em4 and Me8Em17, were located on one side of Re/re at distances of 2.2 and 6.4 cM, whereas the other marker, Me9Em11, was located on the other side of Re/re at a distance of 3.7 cM. These markers could be helpful for the subsequent cloning of the red trait gene and marker-assisted selection in ornamental kale breeding programs.

  2. Relations between circumcision status, sexually transmitted infection history, and HIV serostatus among a national sample of men who have sex with men in the United States.

    Science.gov (United States)

    Jozkowski, Kristen; Rosenberger, Joshua G; Schick, Vanessa; Herbenick, Debby; Novak, David S; Reece, Michael

    2010-08-01

    Circumcision's potential link to HIV/sexually transmitted infections (STI) has been at the center of recent global public health debates. However, data related to circumcision and sexual health remain limited, with most research focused on heterosexual men. This study sought to assess behavioral differences among a large sample of circumcised and noncircumcised men who have sex with men (MSM) in the United States. Data were collected from 26,257 U.S. MSM through an online survey. Measures included circumcision status, health indicators, HIV/STI screening and diagnosis, sexual behaviors, and condom use. Bivariate and regression analyses were conducted to determine differences between HIV/STI status, sexual behaviors, and condom use among circumcised and noncircumcised men. Circumcision status did not significantly predict HIV testing (p > 0.05), or HIV serostatus (p > 0.05), and there were no significant differences based on circumcision status for most STI diagnosis [syphilis, gonorrhea, chlamydia, human papilloma virus (HPV)]. Being noncircumcised was predictive of herpes-2 diagnosis, however, condom use mediated this relationship. These data provide one of the first large national assessments of circumcision among MSM. While being noncircumcised did not increase the likelihood of HIV and most STI infections, results indicated that circumcision was associated with higher rates of condom use, suggesting that those who promote condoms among MSM may need to better understand condom-related behaviors and attitudes among noncircumcised men to enhance the extent to which they are willing to use condoms consistently.

  3. Overwork-related disorders in Japan: recent trends and development of a national policy to promote preventive measures.

    Science.gov (United States)

    Yamauchi, Takashi; Yoshikawa, Toru; Takamoto, Masahiro; Sasaki, Takeshi; Matsumoto, Shun; Kayashima, Kotaro; Takeshima, Tadashi; Takahashi, Masaya

    2017-06-08

    Overwork-related disorders, such as cerebrovascular/cardiovascular diseases (CCVD) and mental disorders due to overwork, are a major occupational and public health issue worldwide, particularly in East Asian countries. This report discusses the recent trend of overwork-related disorders in Japan from the perspective of workers' compensated occupational diseases, as well as the development of a national policy for preventive measures against overwork-related disorders in Japan. Recently, the number of claimed and compensated cases of occupational mental disorders has increased substantially, particularly among young workers, as compared to those of occupational CCVD. In response to these situations and action from society, the Japanese Government passed the "Act on Promotion of Preventive Measures against Karoshi and Other Overwork-Related Health Disorders" in June 2014 to develop a national initiative towards the prevention of overwork-related disorders. Changes in the trend of overwork-related disorders in Japan under a legal foundation and an initiative by the central government should be closely monitored so that other countries can benefit from the experiences.

  4. CHINA RISE SYNDROMES? DRAFTING NATIONAL SCHOOLS OF INTERNATIONAL RELATIONS IN ASIA

    Directory of Open Access Journals (Sweden)

    Chih-Yu Shih

    2014-01-01

    Full Text Available The rise of China is now one of the primary issues in IR literature. However, this development promotes also changes in the structure of the discipline itself, as it fosters self-reflection in the rapid expansion of the Chinese IR school. Moreover, the quest for Chinese theory of IR provokes other Asian countries to conceptualize their place in the world, in order not to be intellectually submerged by the rising neighbour. This theorizing is enlightened by the national traditions of thinking about international politics, largely overseen in the West. This trend promotes genuine liberalization of the discipline. 

  5. Scandinavian links

    DEFF Research Database (Denmark)

    Matthiessen, Christian Wichmann; Knowles, Richard D.

    2014-01-01

    are impressive mega structures spanning international waterways. These waterways between the Baltic Sea and the North Sea have played major roles in history. The length of each of the crossings are around 20 km. The fixed links closes gaps between the Scandinavian and European motorway and rail networks...

  6. Assessment of the administrative burdens for businesses in Bulgaria according to the national legislation related to the European Union internal market

    Directory of Open Access Journals (Sweden)

    Atanas Atanassov

    2017-01-01

    Full Text Available The key objective of the paper is to identify and assess the administrative burdens for businesses in Bulgaria according to the selected national laws related to the EU Internal Market. The study relies on objective data and analytical frameworks with a view to identify and assess the information obligations stemming from selected laws and regulations, including national rules implementing or transposing European legislation. This is an important step in strengthening Bulgaria’s national policy on better regulation for businesses. Information obligations are those arising from regulation to provide information and data to the public sector or third parties. Administrative burdens represent the “extra” administrative costs linked to collecting and providing information that businesses would not normally have to do in the absence of a legal obligation. While regulation is important and necessary, these additional costs represent a burden for businesses. It is a burden for business both in terms of money and time, which diverts resources from productive investments and generally discourages entrepreneurship. The methodology used in the paper is based on the Standard Cost Model for Estimating Administrative Costs established for assessing administrative costs imposed by the EU legislation. The paper is developed taking into account the findings of the OECD and the European Commission. The study outlines the results of the administrative costs and administrative burdens for businesses in Bulgaria of totally measured 742 information obligations (IOs in 16 national laws and regulations to them in 9 selected priority areas during 2013. Even though the study is limited to specific legal acts and to an assessment of costs to business, the results are helpful in understanding the mechanisms by which the administrative costs and administrative burdens accrue. All IOs identified and verified in the paper, related both to national rules implementing or

  7. Evaluating the Effectiveness of National Labor Relations Act Remedies: Analysis and Comparison with Other Workplace Penalty Policies

    OpenAIRE

    Morris M. Kleiner; David Weil

    2010-01-01

    The goal of this paper is to examine the implied penalty policies underlying the remedies created by the National Labor Relations Act (NLRA) in terms of the policies' impact on employer and union behaviors. We present a simple model of deterrence as a means of evaluating workplace penalty policies in terms of their influence on employer behavior, particularly through deterrence effects. We also compare the remedies for violations embodied in the NLRA with penalty policies under other workplac...

  8. Female labour force participation in MENA's manufacturing sector: The implications of firm-related and national factors

    OpenAIRE

    Fakih, Ali; Ghazalian, Pascal L.

    2013-01-01

    The Middle East and North Africa (MENA) region falls behind several other geo-economic regions in terms of women's participation rates in the labour market. This paper examines the implications of firm-related and national factors for Female Labour Force Participation (FLFP) rates in manufacturing firms located in the MENA region. The empirical investigation uses data derived from the World Bank's Enterprise Surveys database and applies fractional logit models to carry out the estimations. Th...

  9. The Longitudinal Relation Between Peer Violent Victimization and Delinquency: Results From a National Representative Sample of U.S. Adolescents

    OpenAIRE

    Jackson, Corrie L.; Hanson, Rochelle F.; Amstadter, Ananda B.; Saunders, Benjamin E.; Kilpatrick, Dean G.

    2012-01-01

    Using a nationally representative sample of adolescents from the United States aged 12 to 17 years (Wave 1, n = 3,614; Wave 2, n = 2,511), this study examined (a) demographic and descriptive information about peer violent victimization (PVV); and (b) the longitudinal relation between a history of PVV and delinquency. Results indicated that 12.4% of adolescents reported lifetime exposure to PVV, and many of these adolescents with a previous history of PVV also reported exposure to other forms ...

  10. Assessing the Brazilian-Chilean bilateral relations : public diplomacy, nation branding and presidential diplomacy

    NARCIS (Netherlands)

    Marcuzzo do Canto Cavalheiro, C.

    2017-01-01

    This thesis explores the main characteristics of the bilateral relations between Brazil and Chile since the late 1990s. The study goes beyond the traditional state-centric approach that solely focuses on the classic channels of traditional diplomacy. Contemporary international relations are not the

  11. 76 FR 58535 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-09-21

    ... Railroad District, (Post-World War II Development in Ottumwa, IA 1944-1959 MPS), Main St. to BNSFRR tracks..., Horace and Rosemond, Farmstead, (Agriculture-Related Resources of Kansas), 25761 151st. St., Leavenworth... Pottawatomie County Heptig, Joseph, Barn, (Agriculture-Related Resources of Kansas), 12115 Antons Rd., Flush...

  12. External costs related to power production technologies. ExternE national implementation for Denmark

    International Nuclear Information System (INIS)

    Schleisner, L.; Sieverts Nielsen, P.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results, to aggregate these site- and technology-specific results to more general figures. The current report covers the detailed information concerning the ExternE methodology. Importance is attached to the computer system used in the project and the assessment of air pollution effects on health, materials and ecological effects. Also the assessment of global warming damages are described. Finally the report covers the detailed information concerning the national implementation for Denmark for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant base on biogas. (au) EU-JOULE 3. 79 tabs., 11 ills., 201 refs

  13. External costs related to power production technologies. ExternE national implementation for Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Schleisner, L; Sieverts Nielsen, P [eds.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results, to aggregate these site- and technology-specific results to more general figures. The current report covers the detailed information concerning the ExternE methodology. Importance is attached to the computer system used in the project and the assessment of air pollution effects on health, materials and ecological effects. Also the assessment of global warming damages are described. Finally the report covers the detailed information concerning the national implementation for Denmark for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant base on biogas. (au) EU-JOULE 3. 79 tabs., 11 ills., 201 refs.

  14. Dragonfly Mercury Project—A citizen science driven approach to linking surface-water chemistry and landscape characteristics to biosentinels on a national scale

    Science.gov (United States)

    Eagles-Smith, Collin A.; Nelson, Sarah J.; Willacker,, James J.; Flanagan Pritz, Colleen M.; Krabbenhoft, David P.

    2016-02-29

    Mercury is a globally distributed pollutant that threatens human and ecosystem health. Even protected areas, such as national parks, are subjected to mercury contamination because it is delivered through atmospheric deposition, often after long-range transport. In aquatic ecosystems, certain environmental conditions can promote microbial processes that convert inorganic mercury to an organic form (methylmercury). Methylmercury biomagnifies through food webs and is a potent neurotoxicant and endocrine disruptor. The U.S. Geological Survey (USGS), the University of Maine, and the National Park Service (NPS) Air Resources Division are working in partnership at more than 50 national parks across the United States, and with citizen scientists as key participants in data collection, to develop dragonfly nymphs as biosentinels for mercury in aquatic food webs. To validate the use of these biosentinels, and gain a better understanding of the connection between biotic and abiotic pools of mercury, this project also includes collection of landscape data and surface-water chemistry including mercury, methylmercury, pH, sulfate, and dissolved organic carbon and sediment mercury concentration. Because of the wide geographic scope of the research, the project also provides a nationwide “snapshot” of mercury in primarily undeveloped watersheds.

  15. Impact assessment of Public Relations in the Fiscal Control Management of the National Agency for Fiscal Administration

    Directory of Open Access Journals (Sweden)

    D.Haranguş

    2013-12-01

    Full Text Available The present study examines the role of public relations as a socio-economic tool of persuasion and educating taxpayers of their civic responsibility to honor fair tax obligations. We propose solutions for improving and restructuring the fiscal control management by diversifying and expanding the range of the instrument constant communication/ public relations and increasing their efficiency in the National Agency for Fiscal Administration, diversifying forms of public communication. The proposed work aims to fill a niche in tax audit work of taxpayers to be felt in practice equitable collection of taxes.

  16. For optimum safety technologies: understanding relations between the different national authorities and the technical support organizations

    International Nuclear Information System (INIS)

    Mahmoud, N.S.; Mostafa Aziz, Mostafa

    2010-01-01

    TSOs describe expert independent organizations, which provide supports for government, regulatory authorities, utilities and industry. The TSO must dispose different competences and objectives in order to deliver to the four independent authorities the technical and scientific knowledge. This comprehensive knowledge, from TSO, should perform through the research and development activities (R and D). Concerning the government, TSOs consider the R and D on the management procedures to characterize the links, to differentiate roles to prevent the overlapping efforts, and finally to build a central data bank in nuclear technologies for the other three authorities. For regulatory organizations, R and D are involved in the regulatory requirements and surveillance processes. On the other side R and D, in case of utilities, activities should focus on the improvement of safety operations for nuclear power and its new generations, and for other nuclear/radiological facilities. Finally, the forth TSOs has R and D targets that should concentrate mainly on material, efficiency, and durability of different equipment and parts involved in the nuclear activities during manufacturing. (author)

  17. Nuclear education and training related issues: Needs and lessons learned in national and international context

    International Nuclear Information System (INIS)

    Lubomir, Sklenka

    2010-01-01

    The paper is focused on nuclear education and training at research reactors and universities. Lack of experts and high educated and skilled professionals in nuclear engineering in the world caused by fast aging of the NPPs and research reactors staff and expected ''nuclear renaissance'' brings a new needs to the universities and research reactors. During the last few years some new trends in nuclear education became visible. Customers expect high quality nuclear education in wide range of knowledge and the complex services, which forces universities and research reactors to bring new challenges in the domain of education and training. State-of-the-art experimental equipment and methodologies specifically developed for the education, networking and dose cooperation between universities and research reactors at national and international levels, and sharing the experimental facilities are the trends which can be noticed today all over the world. Research reactors are suitable for education of students at all academic levels (BSc, MSc and PhD) not only in nuclear engineering, but also in various non-nuclear engineering studies (power engineering, electrical engineering, natural sciences, medical sciences, physical sciences, etc.). An effective way on how to provide the education and training at the research reactor should be started by evaluation of the initial students' background and then adaptation of the educational methodology to that level. Networking and closer co-operation between universities at national and international level in nuclear education started in late nineties in Europe and within a few years several networks were establish. The European Nuclear Education Network (ENEN) as an European regional network with more than 40 European universities was inspiration for creating national networks in Europe (e.g. Belgium, UK, Czech Republic, etc.) and Non-European regional networks (Asia, North America, etc.). Research reactors play an important role in all

  18. 75 FR 39040 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-07-07

    ... Manistee Iron Works Machine Shop, 254 River St., Manistee, 10000477 Wayne County Rosedale Gardens Historic... Berry Morot Car Service Building, (Auto-Related Resources of St. Louis, Missouri [[Page 39041

  19. 78 FR 17429 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-03-21

    ... review, we cannot guarantee that we will be able to do so. Dated: February 21, 2013. J. Paul Loether..., Barn, (Agriculture-Related Resources of Kansas MPS) 200th Ave. & M Rd., Penokee, 13000149 Logan County...

  20. Coding completeness and quality of relative survival-related variables in the National Program of Cancer Registries Cancer Surveillance System, 1995-2008.

    Science.gov (United States)

    Wilson, Reda J; O'Neil, M E; Ntekop, E; Zhang, Kevin; Ren, Y

    2014-01-01

    Calculating accurate estimates of cancer survival is important for various analyses of cancer patient care and prognosis. Current US survival rates are estimated based on data from the National Cancer Institute's (NCI's) Surveillance, Epidemiology, and End RESULTS (SEER) program, covering approximately 28 percent of the US population. The National Program of Cancer Registries (NPCR) covers about 96 percent of the US population. Using a population-based database with greater US population coverage to calculate survival rates at the national, state, and regional levels can further enhance the effective monitoring of cancer patient care and prognosis in the United States. The first step is to establish the coding completeness and coding quality of the NPCR data needed for calculating survival rates and conducting related validation analyses. Using data from the NPCR-Cancer Surveillance System (CSS) from 1995 through 2008, we assessed coding completeness and quality on 26 data elements that are needed to calculate cancer relative survival estimates and conduct related analyses. Data elements evaluated consisted of demographic, follow-up, prognostic, and cancer identification variables. Analyses were performed showing trends of these variables by diagnostic year, state of residence at diagnosis, and cancer site. Mean overall percent coding completeness by each NPCR central cancer registry averaged across all data elements and diagnosis years ranged from 92.3 percent to 100 percent. RESULTS showing the mean percent coding completeness for the relative survival-related variables in NPCR data are presented. All data elements but 1 have a mean coding completeness greater than 90 percent as was the mean completeness by data item group type. Statistically significant differences in coding completeness were found in the ICD revision number, cause of death, vital status, and date of last contact variables when comparing diagnosis years. The majority of data items had a coding

  1. Seismic link at plate boundary

    Indian Academy of Sciences (India)

    time series to determine the causality and related orientation. The resulting link ... Triggering causes changes in the Coulomb stress on a specified fault, which is ... work link shows that the alignment of the links is parallel to the Honshu Trench ...

  2. National action plan 2011-2015 for the management of the radon-related risk. Assessment of the National action plan 2011-2015 for the management of the radon-related risk

    International Nuclear Information System (INIS)

    Grall, Jean-Yves; Crepon, Etienne; Combrexelle, Jean-Denis; Niel, Jean-Christophe

    2011-01-01

    After a presentation of the context, and a brief assessment of the previous national action plan (2005-2008), a first report presents the second national action plan for 2011-2015 with its 8 main axes (implementation of a policy for the management of radon-related risk in existing dwellings, implementation of a regulation for new dwellings, follow-up of the regulation for buildings open to public and of the regulations applied to workers, development of new management tools and of a new operational device to perform building diagnosis and to perform works by building professionals, coordination of the study and research policy) and its 8 main measures. After a synthetic presentation of actions, 30 sheets present the different actions associated with each axis. A second report proposes an assessment of these 30 actions

  3. Physics issues related to the confinement of ICF experiments in the US National Ignition Facility

    International Nuclear Information System (INIS)

    Tobin, M.; Anderson, A.; Latkowski, J.

    1995-04-01

    ICF experiments planned for the proposed US National Ignition Facility (NIF) will produce emissions of neutrons, x rays, debris, and shrapnel. The NIF Target Area (TA) must acceptably confine these emissions and respond to their effects to allow an efficient rate of experiments, from 600 to possibly 1500 per year, and minimal down time for maintenance. Detailed computer code predictions of emissions are necessary to study their effects and impacts on Target Area operations. Preliminary results show that the rate of debris shield transmission loss (and subsequent periodicity of change-out) due to ablated material deposition is acceptable, neutron effects on optics are manageable, and preliminary safety analyses show a facility rating of low hazard, non-nuclear. Therefore, NIF Target Area design features such as fused silica debris shields, refractory first wall coating, and concrete shielding are effective solutions to confinement of ICF experiment emissions

  4. National character and communication. Attitude toward nuclear power plant and its public relations

    International Nuclear Information System (INIS)

    Hayashi, Chikio; Morikawa, Shinichi.

    1994-01-01

    The attitude structure toward nuclear power plant is analyzed with the attitudes toward relevant matters, for example image for nuclear power, knowledge of nuclear power, attitudes toward energy and environment, anxiety about various matters, cognition of risk, social and political attitudes and Japanese national character. Six types are revealed, that is to say, indifference group (13%), strongly favorable group (11%), strongly unfavorable group (9%), fairly favorable group (12%), fairly unfavorable group (5%), and intermediate group (50%). Strongly favorable and unfavorable groups are similar in some points and different in other points, for they are both rational whereas the former is optimistic in the attitude toward science and technology and less interested in environmental problems, and the latter is pessimistic in the attitude toward science and technology and extremely sensitive to environmental problems. The intermediate group has so-called Japanese -like characteristics. It is shown that the emotional persuasion and that based on fact presentation are particularly desirable for this group. (author)

  5. Time trends for injuries and illness, and their relation to performance in the National Basketball Association.

    Science.gov (United States)

    Podlog, Leslie; Buhler, Craig F; Pollack, Harvey; Hopkins, Paul N; Burgess, Paul R

    2015-05-01

    To survey injury/illness in the National Basketball Association over a 25-year period and examine the relationship of injury/illness to team performance. A retrospective correlational design. Trends were examined in reported numbers of players injured/ill during a season and games missed due to injury/illness from seasons ending in 1986 through 2005. This period was compared to years 2006-2010, when NBA teams were allowed to increase the total number of players on the team from 12 to 15. There was a highly significant trend (pBasketball Association up until the expansion of team size in 2006. Following 2006, team expansion was positively associated with decreased injury/illness rates. The latter finding suggests the importance of maintaining a healthy roster with respect to winning outcomes. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  6. National character and communication. Attitude toward nuclear power plant and its public relations

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, Chikio [Institute of Statistical Mathematics, Tokyo (Japan); Morikawa, Shinichi

    1995-10-01

    The attitude structure toward nuclear power plant is analyzed with the attitudes toward relevant matters, for example image for nuclear power, knowledge of nuclear power, attitudes toward energy and environment, anxiety about various matters, cognition of risk, social and political attitudes and Japanese national character. Six types are revealed, that is to say, indifference group (13%), strongly favorable group (11%), strongly unfavorable group (9%), fairly favorable group (12%), fairly unfavorable group (5%), and intermediate group (50%). Strongly favorable and unfavorable groups are similar in some points and different in other points, for they are both rational whereas the former is optimistic in the attitude toward science and technology and less interested in environmental problems, and the latter is pessimistic in the attitude toward science and technology and extremely sensitive to environmental problems. The intermediate group has so-called Japanese-like characteristics. It is shown that the emotional persuasion and that based on fact presentation are particularly desirable for this group. (author)

  7. National character and communication. Attitude toward nuclear power plant and its public relations

    International Nuclear Information System (INIS)

    Hayashi, Chikio; Morikawa, Shinichi.

    1995-01-01

    The attitude structure toward nuclear power plant is analyzed with the attitudes toward relevant matters, for example image for nuclear power, knowledge of nuclear power, attitudes toward energy and environment, anxiety about various matters, cognition of risk, social and political attitudes and Japanese national character. Six types are revealed, that is to say, indifference group (13%), strongly favorable group (11%), strongly unfavorable group (9%), fairly favorable group (12%), fairly unfavorable group (5%), and intermediate group (50%). Strongly favorable and unfavorable groups are similar in some points and different in other points, for they are both rational whereas the former is optimistic in the attitude toward science and technology and less interested in environmental problems, and the latter is pessimistic in the attitude toward science and technology and extremely sensitive to environmental problems. The intermediate group has so-called Japanese-like characteristics. It is shown that the emotional persuasion and that based on fact presentation are particularly desirable for this group. (author)

  8. National character and communication. Attitude toward nuclear power plant and its public relations

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, Chikio [Institute of Statistical Mathematics, Tokyo (Japan); Morikawa, Shinichi

    1994-05-01

    The attitude structure toward nuclear power plant is analyzed with the attitudes toward relevant matters, for example image for nuclear power, knowledge of nuclear power, attitudes toward energy and environment, anxiety about various matters, cognition of risk, social and political attitudes and Japanese national character. Six types are revealed, that is to say, indifference group (13%), strongly favorable group (11%), strongly unfavorable group (9%), fairly favorable group (12%), fairly unfavorable group (5%), and intermediate group (50%). Strongly favorable and unfavorable groups are similar in some points and different in other points, for they are both rational whereas the former is optimistic in the attitude toward science and technology and less interested in environmental problems, and the latter is pessimistic in the attitude toward science and technology and extremely sensitive to environmental problems. The intermediate group has so-called Japanese -like characteristics. It is shown that the emotional persuasion and that based on fact presentation are particularly desirable for this group. (author)

  9. Linking Student Achievement and Teacher Science Content Knowledge about Climate Change: Ensuring the Nations 3 Million Teachers Understand the Science through an Electronic Professional Development System

    Science.gov (United States)

    Niepold, F.; Byers, A.

    2009-12-01

    The scientific complexities of global climate change, with wide-ranging economic and social significance, create an intellectual challenge that mandates greater public understanding of climate change research and the concurrent ability to make informed decisions. The critical need for an engaged, science literate public has been repeatedly emphasized by multi-disciplinary entities like the Intergovernmental Panel on Climate Change (IPCC), the National Academies (Rising Above the Gathering Storm report), and the interagency group responsible for the recently updated Climate Literacy: The Essential Principles of Climate Science. There is a clear need for an American public that is climate literate and for K-12 teachers confident in teaching relevant science content. A key goal in the creation of a climate literate society is to enhance teachers’ knowledge of global climate change through a national, scalable, and sustainable professional development system, using compelling climate science data and resources to stimulate inquiry-based student interest in science, technology, engineering, and mathematics (STEM). This session will explore innovative e-learning technologies to address the limitations of one-time, face-to-face workshops, thereby adding significant sustainability and scalability. The resources developed will help teachers sift through the vast volume of global climate change information and provide research-based, high-quality science content and pedagogical information to help teachers effectively teach their students about the complex issues surrounding global climate change. The Learning Center is NSTA's e-professional development portal to help the nations teachers and informal educators learn about the scientific complexities of global climate change through research-based techniques and is proven to significantly improve teacher science content knowledge.

  10. Relative efficiency of polymerase chain reaction and enzyme-linked immunosorbant assay in determination of viral etiology in congenital cataract in infants

    Directory of Open Access Journals (Sweden)

    Shyamala G

    2008-01-01

    Full Text Available Background: Perinatal viral infections of fetus are among the leading causes of congenital cataract and identifying the viral etiology is important. Objectives: To detect the presence of Rubella virus (RV, herpes simplex virus (HSV and cytomegalovirus (CMV in lens aspirate specimens obtained from patients with congenital cataract and relate the results with serology. Setting and Design: Prospective study carried out in tertiary care hospital. Materials and Methods: Fifty lens aspirates from 50 infants with congenital cataract were subjected to HSV, RV isolation and polymerase chain reaction (PCR for detection of HSV and CMV. Reverse transcription polymerase chain reaction (RT-PCR was applied for RV detection. Peripheral blood specimens were screened for anti-HSV, RV and CMV antibodies by enzyme-linked immunosorbant assay (ELISA. Results: Rubella virus was detected in nine (18% lens aspirates, by nRT-PCR which includes six positive by culture. HSV-2 DNA was detected in nine other lens aspirates, while CMV was not detected by PCR. Serological results did not correlate with the presence of viruses in the lens aspirates. This is the first report of detection of HSV-2 DNA in cases of congenital cataract. Conclusions: Cytomegalovirus may not be playing a significant role in causation of congenital cataract. The role of serology in identifying causative viral infection for congenital cataract needs to be re-evaluated.

  11. Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.

    Science.gov (United States)

    Reddy, Vemuri B; Lerner, Ethan A

    2017-10-20

    Cysteine and serine proteases function via protease-activated and mas-related G-protein-coupled receptors (Mrgprs) to contribute to allergy and inflammation. Der p1 is a cysteine protease and major allergen from the house dust mite and is associated with allergic rhinitis and allergic asthma. Der p1 activates protease-activated receptor 2 and induces the release of the pro-inflammatory cytokine IL-6 from cells. However, the possibility that Der p1 acts on Mrgprs has not been considered. We report here that ratiometric calcium imaging reveals that Der p1 activates the human receptor MRGPRX1 and the mouse homolog MrgprC11, implicated previously in itch. Der p1 cleavage of N-terminal receptor peptides followed by site-directed mutagenesis of the cleavage sites links receptor activation to specific amino acid residues. Der p1 also induced the release of IL-6 from heterologous cells expressing MRGPRX1. In summary, activation of Mrgprs by the allergen Der p1 may contribute to inflammation. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  12. Dietary habits and supplement use in relation to national pregnancy recommendations: data from the EuroPrevall birth cohort.

    Science.gov (United States)

    Oliver, E M; Grimshaw, K E C; Schoemaker, A A; Keil, T; McBride, D; Sprikkelman, A B; Ragnarsdottir, H S; Trendelenburg, V; Emmanouil, E; Reche, M; Fiocchi, A; Fiandor, A; Stanczyk-Przyluska, A; Wilczynski, J; Busacca, M; Sigurdardottir, S T; Dubakiene, R; Rudzeviciene, O; Vlaxos, G D; Beyer, K; Roberts, G

    2014-12-01

    Assessing maternal dietary habits across Europe during pregnancy in relation to their national pregnancy recommendations. A collaborative, multi-centre, birth cohort study in nine European countries was conducted as part of European Union funded EuroPrevall project. Standardised baseline questionnaire data included details of food intake, nutritional supplement use, exposure to cigarette smoke during pregnancy and socio-demographic data. Pregnancy recommendations were collected from all nine countries from the appropriate national organisations. The most commonly taken supplement in pregnancy was folic acid (55.6 % Lithuania-97.8 % Spain) and was favoured by older, well-educated mothers. Vitamin D supplementation across the cohort was very poor (0.3 % Spain-5.1 % Lithuania). There were significant differences in foods consumed in different countries during pregnancy e.g. only 2.7 % Dutch mothers avoided eating peanut, while 44.4 % of British mothers avoided it. Some countries have minimal pregnancy recommendations i.e. Lithuania, Poland and Spain while others have similar, very specific recommendations i.e. UK, the Netherlands, Iceland, Greece. Allergy specific recommendations were associated with food avoidance during pregnancy [relative rate (RR) 1.18 95 % CI 0.02-1.37]. Nutritional supplement recommendations were also associated with avoidance (RR 1.08, 1.00-1.16). Maternal dietary habits and the use of dietary supplements during pregnancy vary significantly across Europe and in some instances may be influenced by national recommendations.

  13. National and Local Vulnerability to Climate-Related Disasters in Latin America

    DEFF Research Database (Denmark)

    Rubin, Olivier; Rossing, Tine

    2012-01-01

    are main determinants of natural disaster mortality in Latin America. Locally, the region's poor are particularly susceptible to climate-related natural hazards. As a result of their limited access to capital, adaptation based on social assets constitutes an effective coping strategy. Evidence from Bolivia......The Latin American region is particularly prone to climate-related natural hazards. However, this article argues that natural hazards are only partly to blame for the region's vulnerability to natural disasters with quantitative evidence suggesting instead that income per capita and inequality...... and Belize illustrates the importance of social assets in protecting the most vulnerable against natural disasters....

  14. Victimization and adversity among children experiencing war-related parental absence or deployment in a nationally representative US sample.

    Science.gov (United States)

    Turner, Heather A; Finkelhor, David; Hamby, Sherry; Henly, Megan

    2017-05-01

    This study compares children and youth who have experienced lifetime war-related parental absence or deployment with those having no such history on a variety of victimization types, non-victimization adversity, trauma symptoms, and delinquency; and assesses whether cumulative adversity and victimization help to explain elevated emotional and behavioral problems among children of parents who have experienced war-related absence or deployment. The National Surveys of Children's Exposure to Violence (NatSCEV) are comprised of three cross-sectional telephone surveys conducted in 2008, 2011, and 2014. Data were collected on the experiences of children aged one month to seventeen years. In each survey, interviews were conducted with youth 10-17 years old and with caregivers of children 0-9 years old. The analyses use pooled data from all three U.S. nationally-representative samples (total sample size of 13,052). Lifetime parental war-related absence or deployment was a marker for elevated childhood exposure to a wide array of victimization and adversity types. Cumulative past year exposure to multiple forms of victimization and adversity fully explained elevated trauma symptoms and delinquency in this population of children. Given the breadth of victimization and adversity risk, children with histories of parental war-related absence or deployment, as well as their families, represent important target groups for broad-based prevention and interventions to reduce exposure and ameliorate consequences when it does occur. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. 78 FR 31847 - Designation of National Security Positions in the Competitive Service, and Related Matters

    Science.gov (United States)

    2013-05-28

    ...) Positions requiring eligibility for access to Top Secret or ``Q'' classified information; (ii) Positions... information classified at the Top Secret or ``Q'' level; (xix) Positions working with significant life... intelligence-related Special Sensitive information, requiring involvement in Top Secret Special Access Programs...

  16. Laterality related to the successive selection of Dutch national youth soccer players

    NARCIS (Netherlands)

    Verbeek, Jan; Elferink-Gemser, Marije T.; Jonker, Laura; Huijgen, Barbara C. H.; Visscher, Chris

    2017-01-01

    In the general population, estimates of left-foot preference are around 20%. In soccer, specific tasks create positional demands, requiring 40% of the players to be left-footed. Whether and how this is related to the selection of players is unknown. To examine the successive selection of soccer

  17. 78 FR 40202 - National Council on Federal Labor-Management Relations Meeting

    Science.gov (United States)

    2013-07-03

    ... Services,'' which was signed by the President on December 9, 2009. Along with its other responsibilities... the responsibilities and functions listed in section 1(b) of the Executive Order. The meetings are... information. FOR FURTHER INFORMATION CONTACT: Thomas Wachter, Labor Relations Manager, Partnership and Labor...

  18. College law enforcement and security department responses to alcohol-related incidents: a national study.

    Science.gov (United States)

    Bernat, Debra H; Lenk, Kathleen M; Nelson, Toben F; Winters, Ken C; Toomey, Traci L

    2014-08-01

    Campus police and security personnel are often the first to respond to alcohol-related incidents on campus. The purpose of this study is to examine how campus law enforcement and security respond to alcohol-related incidents, and how consequences and communication differ based on characteristics of the incident. Directors of campus police/security from 343 colleges across the United States completed a survey regarding usual practice following serious, underage, and less serious alcohol incidents on and off campus. Campus law enforcement and security most commonly reported contacting campus officials. A minority reported issuing citations and referring students to the health center. Enforcement actions were more commonly reported for serious and underage incidents than for less serious incidents. Large (vs. small) colleges, public (vs. private) colleges, and those located in small (vs. large) towns more consistently reported taking actions against drinkers. Understanding how campus police and security respond to alcohol-related incidents is essential for reducing alcohol-related problems on college campuses. Copyright © 2014 by the Research Society on Alcoholism.

  19. Vegetation-environment relations of the Chisos Mountains, Big Bend National Park, Texas

    Science.gov (United States)

    Helen M. Poulos; Ann E. Camp

    2005-01-01

    The Sky Island Archipelagos of the Sierra Madre Oriental and Occidental contain a unique array of endemic flora and fauna. Plant species composition in these elevationally restricted forests is thought to vary in relation to environmental gradients. This study quantifies plant population abundance and spatial distribution patterns in pine-oak woodlands of Big Bend...

  20. Relative age effect and the re-selection of Danish male handball players for national teams

    DEFF Research Database (Denmark)

    Wrang, Christian Meedom; Rossing, Niels Nygaard; Lilholt, Rasmus Mølgaard

    2018-01-01

    The relationship between date of birth and expertise in various sports is well established, and known as the relative age effect (RAE). However, new results in e.g. Canadian Hockey (Gibbs et al., 2012) and British cricket and rugby (McCarthy & Collins, 2014; McCarthy, Collins, & Court, 2015) have...

  1. Hungarian national report on activities related to operator support systems for nuclear power plants

    International Nuclear Information System (INIS)

    Adorjan, F.; Lux, I.; Vegh, J.; Vegh, E.

    1996-01-01

    Computerized operator support systems and related activities in Hungary are summarized. Systems developed in the past, presently developed and used as well as being in a planning phase are briefly described. Activity of the Hungarian participants in the framework of the co-ordinated project on operator support systems for nuclear power plant is summarized. (author). 55 refs

  2. First Nations: Race, Class, and Gender Relations. Canadian Plains Reprint Series 7.

    Science.gov (United States)

    Wotherspoon, Terry; Satzewich, Vic

    Canadian social life and public policy are increasingly influenced by Aboriginal people, their roles in Canadian society, and the issues that concern them. Drawing on a political economy perspective, this book provides a systematic analysis of how changing social dynamics, organized particularly around race, class, and gender relations, have…

  3. A two-state comparative implementation of peer-support intervention to link veterans to health-related services after incarceration: a study protocol.

    Science.gov (United States)

    Simmons, Molly M; Fincke, Benjamin G; Drainoni, Mari-Lynn; Kim, Bo; Byrne, Tom; Smelson, David; Casey, Kevin; Ellison, Marsha L; Visher, Christy; Blue-Howells, Jessica; McInnes, D Keith

    2017-09-12

    Approximately 600,000 persons are released from prison annually in the United States. Relatively few receive sufficient re-entry services and are at risk for unemployment, homelessness, poverty, substance abuse relapse and recidivism. Persons leaving prison who have a mental illness and/or a substance use disorder are particularly challenged. This project aims to create a peer mentor program to extend the reach and effectiveness of reentry services provided by the Department of Veterans' Affairs (VA). We will implement a peer support for reentry veterans sequentially in two states. Our outcome measures are 1) fidelity of the intervention, 2) linkage to VA health care and, 3) continued engagement in health care. The aims for this project are as follows: (1) Conduct contextual analysis to identify VA and community reentry resources, and describe how reentry veterans use them. (2) Implement peer-support, in one state, to link reentry veterans to Veterans' Health Administration (VHA) primary care, mental health, and SUD services. (3) Port the peer-support intervention to another, geographically, and contextually different state. This intervention involves a 2-state sequential implementation study (Massachusetts, followed by Pennsylvania) using a Facilitation Implementation strategy. We will conduct formative and summative analyses, including assessment of fidelity, and a matched comparison group to evaluate the intervention's outcomes of veteran linkage and engagement in VHA health care (using health care utilization measures). The study proceeds in 3 phases. We anticipate that a peer support program will be effective at improving the reentry process for veterans, particularly in linking them to health, mental health, and SUD services and helping them to stay engaged in those services. It will fill a gap by providing veterans with access to a trusted individual, who understands their experience as a veteran and who has experienced justice involvement. The outputs from

  4. Childhood Household Dysfunction, Social Inequality and Alcohol Related Illness in Young Adulthood. A Swedish National Cohort Study.

    Directory of Open Access Journals (Sweden)

    Karl Gauffin

    Full Text Available The aim of this paper is to estimate the cumulative effect of childhood household dysfunction (CHD on alcohol related illness and death later in life and to test the interaction between CHD and socioeconomic background. The study utilised Swedish national registers including data of a Swedish national cohort born 1973-82 (n = 872,912, which was followed from age 18 to 29-40 years. Cox regression analyses were used to calculate hazard ratios (HR for alcohol related illness or death in young adulthood. The CHD measure consisted of seven indicators: parental alcohol/drug misuse, mental health problems, criminality, death, divorce, social assistance, and child welfare interventions. Childhood socioeconomic position (SEP was indicated by parental occupational status. Outcomes were alcohol related inpatient hospital care, specialised outpatient care or deaths. Using the highest socioeconomic group without CHD experience as a reference, those in the same socioeconomic group with one indicator of CHD had HRs of 2.1 [95% CI: 1.7-2.5], two CHD indicators 5.6 [4.4-7.1], three or more indicators 9.4 [7.1-12.4] for retrieving inpatient care. Socioeconomic disadvantage further increased the risks-those with low socioeconomic background and three CHD indicators or more had a HR of 12.5 [10.9-14.3]. Testing for interaction suggests that the combined HRs deviates from additivity [Synergy index: 1.6, 95% CI: 1.4-1.9]. The results for outpatient care were similar, but not as pronounced. In conclusion, this Swedish national cohort study shows that childhood household dysfunction is strongly and cumulatively associated to alcohol related illness later in life and that it interacts with socioeconomic disadvantage.

  5. Intermittent Divertor Filaments in the National Spherical Torus Experiment and Their Relation to Midplane Blobs

    International Nuclear Information System (INIS)

    Maqueda, R.J.; Stotler, D.P.

    2010-01-01

    While intermittent filamentary structures, also known as blobs, are routinely seen in the low-field-side scrape-off layer of the National Spherical Torus Experiment (NSTX) (Ono et al 2000 Nucl. Fusion 40 557), fine structured filaments are also seen on the lower divertor target plates of NSTX. These filaments, not associated with edge localized modes, correspond to the interaction of the turbulent blobs seen near the midplane with the divertor plasma facing components. The fluctuation level of the neutral lithium light observed at the divertor, and the skewness and kurtosis of its probability distribution function, is similar to that of midplane blobs seen in D α ; e.g. increasing with increasing radii outside the outer strike point (OSP) (separatrix). In addition, their toroidal and radial movement agrees with the typical movement of midplane blobs. Furthermore, with the appropriate magnetic topology, i.e. mapping between the portion of the target plates being observed into the field of view of the midplane gas puff imaging diagnostic, very good correlation is observed between the blobs and the divertor filaments. The correlation between divertor plate filaments and midplane blobs is lost close to the OSP. This latter observation is consistent with the existence of 'magnetic shear disconnection' due to the lower X-point, as proposed by Cohen and Ryutov (1997 Nucl. Fusion 37 621).

  6. A financial analysis of revision hip arthroplasty: the economic burden in relation to the national tariff.

    Science.gov (United States)

    Vanhegan, I S; Malik, A K; Jayakumar, P; Ul Islam, S; Haddad, F S

    2012-05-01

    Revision arthroplasty of the hip is expensive owing to the increased cost of pre-operative investigations, surgical implants and instrumentation, protracted hospital stay and drugs. We compared the costs of performing this surgery for aseptic loosening, dislocation, deep infection and peri-prosthetic fracture. Clinical, demographic and economic data were obtained for 305 consecutive revision total hip replacements in 286 patients performed at a tertiary referral centre between 1999 and 2008. The mean total costs for revision surgery in aseptic cases (n = 194) were £11 897 (sd 4629), for septic revision (n = 76) £21 937 (sd 10 965), for peri-prosthetic fracture (n = 24) £18 185 (sd 9124), and for dislocation (n = 11) £10 893 (sd 5476). Surgery for deep infection and peri-prosthetic fracture was associated with longer operating times, increased blood loss and an increase in complications compared to revisions for aseptic loosening. Total inpatient stay was also significantly longer on average (p < 0.001). Financial costs vary significantly by indication, which is not reflected in current National Health Service tariffs.

  7. Game injuries in relation to game schedules in the National Basketball Association.

    Science.gov (United States)

    Teramoto, Masaru; Cross, Chad L; Cushman, Daniel M; Maak, Travis G; Petron, David J; Willick, Stuart E

    2017-03-01

    Injury management is critical in the National Basketball Association (NBA), as players experience a wide variety of injuries. Recently, it has been suggested that game schedules, such as back-to-back games and four games in five days, increase the risk of injuries in the NBA. The aim of this study was to examine the association between game schedules and player injuries in the NBA. Descriptive epidemiology study. The present study analyzed game injuries and game schedules in the 2012-13 through 2014-15 regular seasons. Game injuries by game schedules and players' profiles were examined using an exact binomial test, the Fisher's exact test and the Mann-Whitney-Wilcoxon test. A Poisson regression analysis was performed to predict the number of game injuries sustained by each player from game schedules and injured players' profiles. There were a total of 681 cases of game injuries sustained by 280 different players during the three years (total N=1443 players). Playing back-to-back games or playing four games in five days alone was not associated with an increased rate of game injuries, whereas a significant positive association was found between game injuries and playing away from home (pNBA. The findings could be useful for designing optimal game schedules in the NBA as well as helping NBA teams make adjustments to minimize game injuries. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  8. The role of the United Nations Scientific Committee on the Effects of Atomic Radiation in relation to medical radiation exposures

    International Nuclear Information System (INIS)

    Shrimpton, P.C.

    2001-01-01

    In 1955, growing global concerns about ionizing radiation led the General Assembly of the United Nations to establish the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). The mandate of this committee, which presently includes 21 Member States, is to assess and report on the levels and effects of exposure to ionizing radiation. Accordingly, UNSCEAR applies scientific judgement in undertaking comprehensive reviews and evaluations concerning radiation and maintains an independent and neutral position in drawing its conclusions. These are published in authoritative reports to the UN General Assembly, with there having been 14 such substantive reports, with technical annexes, since 1958. The information provided by UNSCEAR assists the General Assembly in making recommendations in relation, for example, to international collaboration in the field of health. Governments and organizations all over the world rely on the committee's evaluations as the scientific basis for estimating radiation risk, establishing radiation protection and safety standards, and regulating radiation sources

  9. Current management of pregnancy-related low back pain: a national cross-sectional survey of U.K. physiotherapists.

    Science.gov (United States)

    Bishop, A; Holden, M A; Ogollah, R O; Foster, N E

    2016-03-01

    Pregnancy-related low back pain (LBP) is very common. Evidence from a systematic review supports the use of exercise and acupuncture, although little is known about the care received by women with pregnancy-related back pain in the U.K. To describe current acupuncture and standard care management of pregnancy-related LBP by U.K. physiotherapists. Cross-sectional survey of physiotherapists with experience of treating women with pregnancy-related LBP from three professional networks of the Chartered Society of Physiotherapy. In total, 1093 physiotherapists were mailed a questionnaire. The questionnaire captured respondents' demographic and practice setting information, and experience of managing women with pregnancy-related back pain, and investigated the reported management of pregnancy-related LBP using a patient case vignette of a specific, 'typical' case. The overall response rate was 58% (629/1093). Four hundred and ninety-nine physiotherapists had experience of treating women with pregnancy-related LBP and were included in the analysis. Most respondents worked wholly or partly in the U.K. National Health Service (78%). Most respondents reported that they treat patients with pregnancy-related LBP in three to four one-to-one treatment sessions over 3 to 6 weeks. The results show that a range of management strategies are employed for pregnancy-related LBP, and multimodal management is common. The most common reported treatment was home exercises (94%), and 24% of physiotherapists reported that they would use acupuncture with the patient described in the vignette. This study provides the first robust data on the management of pregnancy-related LBP by U.K. physiotherapists. Multimodal management is common, although exercise is the most frequently used treatment for pregnancy-related LBP. Acupuncture is used less often for this patient group. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. American National Standard: guidelines for evaluating site-related geotechnical parameters at nuclear power sites

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    This standard presents guidelines for evaluating site-related geotechnical parameters for nuclear power sites. Aspects considered include geology, ground water, foundation engineering, and earthwork engineering. These guidelines identify the basic geotechnical parameters to be considered in site evaluation, and in the design, construction, and performance of foundations and earthwork aspects for nuclear power plants. Also included are tabulations of typical field and laboratory investigative methods useful in identifying geotechnical parameters. Those areas where interrelationships with other standards may exist are indicated

  11. Greenland as a self-governing sub-national territory in international relations: past, current and future perspectives

    DEFF Research Database (Denmark)

    Ackrén, Maria; Jakobsen, Uffe

    2015-01-01

    Greenland was used by the US as a platform and as an extended arm within its security and foreign policy during the World War II and the cold war. After this things changed, although Greenland remained important in Danish-US relations under the umbrella of NATO. Nowadays, the geostrategic position...... of Greenland between North America and Europe is gaining fresh prominence in the race for natural resources in the Arctic. Many issues arise from the prospective opening of the Arctic, all of which may have fateful impacts on future development in the region. Climate change, claims related to the extension....... This article reviews developments from the World War II to the present regarding international relations from a Greenlandic perspective. As a self-governing sub-national territory within the realm of Denmark, Greenland does not have the ultimate decision-making power within foreign and security policy. The new...

  12. One or two nation projects? Discourse on inequalities and equality-related policies in South Africa and Brazil

    Directory of Open Access Journals (Sweden)

    Bernhard Leubolt

    2015-09-01

    Full Text Available AbstractThis contribution focuses on the social production and reproduction of social inequalities in Brazil and South Africa. It aims at interlinking different theoretical perspectives and applying them to a comparative analysis of inequality-related policies. Resorting to strategic-relational institutionalism, the historical heritage of discourse formation and the institutionalization of inequality regimes in the two countries to inform the analysis of the more recent conjuncture will be analysed. While South Africa is an example of formal racist discrimination, the Brazilian inequality regime worked on more informal patterns. The different historical heritage influences current foci of equality-related policies, which tend to be dominantly anti-racist in South Africa, while focusing on poverty reduction in Brazil during the recent years. The latter experience tended more towards a discourse of a ‘common interest’ and was better able to institutionalize policies to reduce income inequalities. South Africa is still discursively divided into ‘two nations’. Social uplifting for Africans linked to the governing parties was only partially accompanied by improved living conditions for the poor majority of Africans. Both countries are significantly structured by the respective historical heritage concerning both the creation and the reduction of inequalities. The Brazilian ‘one nation’ discourse was more successful in promoting equality-related policies than its ‘two nations’ counterpart in South Africa. Despite important improvements, both countries are now in critical junctures and societal contradictions are beginning to create new crisis tendencies.

  13. Surgeon length of service and risk-adjusted outcomes: linked observational analysis of the UK National Adult Cardiac Surgery Audit Registry and General Medical Council Register.

    Science.gov (United States)

    Hickey, Graeme L; Grant, Stuart W; Freemantle, Nick; Cunningham, David; Munsch, Christopher M; Livesey, Steven A; Roxburgh, James; Buchan, Iain; Bridgewater, Ben

    2014-09-01

    To explore the relationship between in-hospital mortality following adult cardiac surgery and the time since primary clinical qualification for the responsible consultant cardiac surgeon (a proxy for experience). Retrospective analysis of prospectively collected national registry data over a 10-year period using mixed-effects multiple logistic regression modelling. Surgeon experience was defined as the time between the date of surgery and award of primary clinical qualification. UK National Health Service hospitals performing cardiac surgery between January 2003 and December 2012. All patients undergoing coronary artery bypass grafts and/or valve surgery under the care of a consultant cardiac surgeon. All-cause in-hospital mortality. A total of 292,973 operations performed by 273 consultant surgeons (with lengths of service from 11.2 to 42.0 years) were included. Crude mortality increased approximately linearly until 33 years service, before decreasing. After adjusting for case-mix and year of surgery, there remained a statistically significant (p=0.002) association between length of service and in-hospital mortality (odds ratio 1.013; 95% CI 1.005-1.021 for each year of 'experience'). Consultant cardiac surgeons take on increasingly complex surgery as they gain experience. With this progression, the incidence of adverse outcomes is expected to increase, as is demonstrated in this study. After adjusting for case-mix using the EuroSCORE, we observed an increased risk of mortality in patients operated on by longer serving surgeons. This finding may reflect under-adjustment for risk, unmeasured confounding or a real association. Further research into outcomes over the time course of surgeon's careers is required. © The Royal Society of Medicine.

  14. Permanent link

    Indian Academy of Sciences (India)

    This special issue of Sadhana is a compilation of papers selected from those presented at the 7th National Power Electronics Conference (NPEC), held at the Indian Institute of Technology, Bombay, on 21–23 December 2015. From among the papers presented in NPEC-2017, selected papers were peer-reviewed for ...

  15. Missing Links

    DEFF Research Database (Denmark)

    Lange, Ida Sofie Gøtzsche; Laursen, Lea Louise Holst; Lassen, Claus

    2014-01-01

    passerer gennem området i form af turister, forretningsrejsende, gods og offshore-industri, og det har en national motorvej, en togrute og færgeforbindelser til en række nordiske lande. Dog oplever byen stadig de samme problemer som en række andre perifere byer: fraflytning, bymæssigt forfald, mangel på...

  16. Operative links

    DEFF Research Database (Denmark)

    Wistoft, Karen

    2010-01-01

    and have been the object of great expectations concerning the ability to incorporate health concerns into every welfare area through health promotion strategies. The paper draws on results and analyses of a collective research project funded by the Danish National Research Council and carried out...

  17. Public and private maternal health service capacity and patient flows in Southern Tanzania: using a geographic information system to link hospital and national census data.

    Science.gov (United States)

    Tabatabai, Patrik; Henke, Stefanie; Sušac, Katharina; Kisanga, Oberlin M E; Baumgarten, Inge; Kynast-Wolf, Gisela; Ramroth, Heribert; Marx, Michael

    2014-01-01

    Strategies to improve maternal health in low-income countries are increasingly embracing partnership approaches between public and private stakeholders in health. In Tanzania, such partnerships are a declared policy goal. However, implementation remains challenging as unfamiliarity between partners and insufficient recognition of private health providers prevail. This hinders cooperation and reflects the need to improve the evidence base of private sector contribution. To map and analyse the capacities of public and private hospitals to provide maternal health care in southern Tanzania and the population reached with these services. A hospital questionnaire was applied in all 16 hospitals (public n=10; private faith-based n=6) in 12 districts of southern Tanzania. Areas of inquiry included selected maternal health service indicators (human resources, maternity/delivery beds), provider-fees for obstetric services and patient turnover (antenatal care, births). Spatial information was linked to the 2002 Population Census dataset and a geographic information system to map patient flows and socio-geographic characteristics of service recipients. The contribution of faith-based organizations (FBOs) to hospital maternal health services is substantial. FBO hospitals are primarily located in rural areas and their patient composition places a higher emphasis on rural populations. Also, maternal health service capacity was more favourable in FBO hospitals. We approximated that 19.9% of deliveries in the study area were performed in hospitals and that the proportion of c-sections was 2.7%. Mapping of patient flows demonstrated that women often travelled far to seek hospital care and where catchment areas of public and FBO hospitals overlap. We conclude that the important contribution of FBOs to maternal health services and capacity as well as their emphasis on serving rural populations makes them promising partners in health programming. Inclusive partnerships could increase

  18. National stereotypes of older people's competence are related to older adults' participation in paid and volunteer work.

    Science.gov (United States)

    Bowen, Catherine E; Skirbekk, Vegard

    2013-11-01

    Why are older people perceived as more competent in some countries relative to others? In the current study, we investigate the extent to which national variation in perceptions of older people's competence is systematically related to national variation in the extent to which older people participate in paid and volunteer work. We used multilevel regression to analyze data from the European Social Survey and test the relationship between perceptions of older people's competence and older people's participation in paid and volunteer work across 28 countries. We controlled for a number of potentially confounding variables, including life expectancy as well as the gender ratio and average education of the older population in each country. We controlled for the average objective cognitive abilities of the older population in a subsample of 11 countries. Older people were perceived as more competent in countries in which more older people participated in paid or volunteer work, independent of life expectancy and the average education, gender makeup, and average cognitive abilities of the older population. The results suggest that older people's participation in paid and volunteer work is related to perceptions of older people's competence independent of older people's actual competence.

  19. Work-related musculoskeletal symptoms among otolaryngologists by subspecialty: A national survey.

    Science.gov (United States)

    Ho, Thuy-Van Tina; Hamill, Chelsea S; Sykes, Kevin J; Kraft, Shannon M

    2018-03-01

    Given the high prevalence of work-related musculoskeletal symptoms, increased appreciation for workplace ergonomics is critical. The purpose of this study is to assess work-related musculoskeletal symptoms and injury among otolaryngologists across subspecialties, as well as to quantify the understanding and application of ergonomic principles in the operating room. Cross-sectional study. An online REDCap survey was distributed electronically to University of Kansas faculty, alumni, and residents; members of the American Academy of Facial Plastic and Reconstructive Surgery; and residency program coordinators for distribution to residents and faculty between August 2016 and March 2017. The survey assessed caseload, ergonomic practices, and associated musculoskeletal symptoms by type of procedure and impact of symptoms on surgeon practice. The survey was distributed to 3,006 individuals. We received 377 responses (12.5%), with 63.9% reporting symptoms. The majority of respondents began to experience symptoms in residency or fellowship. Neck and shoulder were the most affected body areas across all types of surgeries. One-third of surgeons were formally taught or actively sought information on ergonomics principles. Among those who applied ergonomics in practice, 69.6% observed improvement in their symptoms. Although musculoskeletal issues are prevalent among otolaryngologists, awareness of surgical ergonomics principles among otolaryngologists remains limited. Early instruction in ergonomic principles is important because work-related musculoskeletal symptoms commonly present in residency. Most respondents reporting the application of ergonomic principles also acknowledge symptom improvement. NA. Laryngoscope, 128:632-640, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  20. Impact of the energy-related inventions program on the national economy

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A.; Morell, J.A.; Snell, S.A.; Kerley, C.R.

    1987-01-01

    The market entry, sales, and employment data presented in this paper suggest that ERIP has been able to efficiently produce positive economic impacts. It is likely that the documented successes of ERIP's inventors will be even greater as their projects mature and more current commercialization information is collected. Survey data presented elsewhere indicate that the ERIP financial support, endorsement, encouragement, and commercialization education are viewed by participants as the most important benefits of the program (Brown, Morell, Snell, Soderstrom, and Friggle, 1987). Other federal, state, and local programs might profit substantially from modelling the composition and delivery of their assistance after the Energy-Related Inventions Program.

  1. 2011-2015 National action plan for the management of radon-related risk

    International Nuclear Information System (INIS)

    2011-01-01

    After an assessment of the 2005-2008 action plan, this report presents the 2011-2015 plan. It comprises five main axis: the implementation of a policy regarding the management of the radon-related risk in existing dwellings, the implementation of a regulation for new dwellings, the follow-up of the regulation regarding public places and that applicable to workers, the development and the implementation of new management tools for the diagnosis of buildings and works performed by professionals, and the coordination of policy regarding investigation and research. Each axis comprises several actions which are defined and presented. Eight key measures are also defined

  2. Exploring the relationship between national economic indicators and relative fitness and frailty in middle-aged and older Europeans

    Science.gov (United States)

    Theou, Olga; Brothers, Thomas D.; Rockwood, Michael R.; Haardt, David; Mitnitski, Arnold; Rockwood, Kenneth

    2013-01-01

    Background: on an individual level, lower-income has been associated with disability, morbidity and death. On a population level, the relationship of economic indicators with health is unclear. Objective: the purpose of this study was to evaluate relative fitness and frailty in relation to national income and healthcare spending, and their relationship with mortality. Design and setting: secondary analysis of data from the Survey of Health, Ageing and Retirement in Europe (SHARE); a longitudinal population-based survey which began in 2004. Subjects: a total of 36,306 community-dwelling people aged 50 and older (16,467 men; 19,839 women) from the 15 countries which participated in the SHARE comprised the study sample. A frailty index was constructed as the proportion of deficits present in relation to the 70 deficits available in SHARE. The characteristics of the frailty index examined were mean, prevalence of frailty and proportion of the fittest group. Results: the mean value of the frailty index was lower in higher-income countries (0.16 ± 0.12) than in lower-income countries (0.20 ± 0.14); the overall mean frailty index was negatively correlated with both gross domestic product (r = −0.79; P < 0.01) and health expenditure (r = −0.63; P < 0.05). Survival in non-frail participants at 24 months was not associated with national income (P = 0.19), whereas survival in frail people was greater in higher-income countries (P < 0.05). Conclusions: a country's level of frailty and fitness in adults aged 50+ years is strongly correlated with national economic indicators. In higher-income countries, not only is the prevalence of frailty lower, but frail people also live longer. PMID:23443511

  3. Age-Related Imbalance Is Associated With Slower Walking Speed: An Analysis From the National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Xie, Yanjun J; Liu, Elizabeth Y; Anson, Eric R; Agrawal, Yuri

    Walking speed is an important dimension of gait function and is known to decline with age. Gait function is a process of dynamic balance and motor control that relies on multiple sensory inputs (eg, visual, proprioceptive, and vestibular) and motor outputs. These sensory and motor physiologic systems also play a role in static postural control, which has been shown to decline with age. In this study, we evaluated whether imbalance that occurs as part of healthy aging is associated with slower walking speed in a nationally representative sample of older adults. We performed a cross-sectional analysis of the previously collected 1999 to 2002 National Health and Nutrition Examination Survey (NHANES) data to evaluate whether age-related imbalance is associated with slower walking speed in older adults aged 50 to 85 years (n = 2116). Balance was assessed on a pass/fail basis during a challenging postural task-condition 4 of the modified Romberg Test-and walking speed was determined using a 20-ft (6.10 m) timed walk. Multivariable linear regression was used to evaluate the association between imbalance and walking speed, adjusting for demographic and health-related covariates. A structural equation model was developed to estimate the extent to which imbalance mediates the association between age and slower walking speed. In the unadjusted regression model, inability to perform the NHANES balance task was significantly associated with 0.10 m/s slower walking speed (95% confidence interval: -0.13 to -0.07; P imbalance mediates 12.2% of the association between age and slower walking speed in older adults. In a nationally representative sample, age-related balance limitation was associated with slower walking speed. Balance impairment may lead to walking speed declines. In addition, reduced static postural control and dynamic walking speed that occur with aging may share common etiologic origins, including the decline in visual, proprioceptive, and vestibular sensory and

  4. Road traffic related mortality in Vietnam: Evidence for policy from a national sample mortality surveillance system

    Directory of Open Access Journals (Sweden)

    Ngo Anh D

    2012-07-01

    Full Text Available Abstract Background Road traffic injuries (RTIs are among the leading causes of mortality in Vietnam. However, mortality data collection systems in Vietnam in general and for RTIs in particular, remain inconsistent and incomplete. Underlying distributions of external causes and body injuries are not available from routine data collection systems or from studies till date. This paper presents characteristics, user type pattern, seasonal distribution, and causes of 1,061 deaths attributable to road crashes ascertained from a national sample mortality surveillance system in Vietnam over a two-year period (2008 and 2009. Methods A sample mortality surveillance system was designed for Vietnam, comprising 192 communes in 16 provinces, accounting for approximately 3% of the Vietnamese population. Deaths were identified from commune level data sources, and followed up by verbal autopsy (VA based ascertainment of cause of death. Age-standardised mortality rates from RTIs were computed. VA questionnaires were analysed in depth to derive descriptive characteristics of RTI deaths in the sample. Results The age-standardized mortality rates from RTIs were 33.5 and 8.5 per 100,000 for males and females respectively. Majority of deaths were males (79%. Seventy three percent of all deaths were aged from 15 to 49 years and 58% were motorcycle users. As high as 80% of deaths occurred on the day of injury, 42% occurred prior to arrival at hospital, and a further 29% occurred on-site. Direct causes of death were identified for 446 deaths (42% with head injuries being the most common cause attributable to road traffic injuries overall (79% and to motorcycle crashes in particular (78%. Conclusion The VA method can provide a useful data source to analyse RTI mortality. The observed considerable mortality from head injuries among motorcycle users highlights the need to evaluate current practice and effectiveness of motorcycle helmet use in Vietnam. The high number of

  5. Validity of preeclampsia-related diagnoses recorded in a national hospital registry and in a postpartum interview of the women

    DEFF Research Database (Denmark)

    Klemmensen, Ase K; Olsen, Sjurdur F; Osterdal, Marie Louise

    2007-01-01

    In a population-based sample, the authors examined the validity of preeclampsia and related diagnoses recorded in a mandatory Danish national hospital discharge registry and in a standardized telephone interview of women who gave birth between 1998 and 2002. Using a "gold standard" for preeclamps...... defined in accordance with the guidelines from the American College of Obstetricians and Gynecologists, the authors reviewed hospital charts of 3,039 women and found that 61 of 88 preeclampsia cases (69.3%) and 24 of 55 cases of serious subtypes of preeclampsia (43.6%) were recorded...

  6. Preliminary study of highly cross-linked hyaluronic acid-based combination therapy for management of knee osteoarthritis-related pain

    Directory of Open Access Journals (Sweden)

    Palmieri B

    2013-01-01

    Full Text Available Beniamino Palmieri,1,2 Valentina Rottigni,1,2 Tommaso Iannitti2,31Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy; 2Poliambulatorio del Secondo Parere, Modena, Italy; 3Department of Physiology, School of Medicine, University of Kentucky Medical Center, Lexington, KY, USABackground: Hyaluronic acid has been extensively used for treatment of knee osteoarthritis due to its anti-inflammatory properties and its ability to act as a synovial lubricant. Furthermore, it has found application in combination with other drugs in the dermatological field and in pre-clinical studies in animal models of osteoarthritis. Experimental evidence suggests that a combination of this macromolecule with other drugs may act as a slow-release depot. However, to date, to the best of our knowledge, no one has tested local intra-articular delivery of highly cross-linked hyaluronic acid combined with bisphosphonate or nonsteroidal anti-inflammatory drugs for management of knee osteoarthritis pain in the clinical setting. The aim of the present randomized double-blind study was to investigate, for the first time, the effect of a highly cross-linked hyaluronic acid, Variofill®, alone or in combination with diclofenac sodium or sodium clodronate, for management of bilateral knee osteoarthritis-related pain.Methods: Sixty-two patients with symptomatic bilateral medial tibiofemoral knee osteoarthritis (Kellgren–Lawrence grade II and III and pain in both knees corresponding to a daily visual analog scale (VAS score ≥ 30 in the month before the beginning of the study were included in this investigation. Patients were divided into three groups: group 1, treated with an injection of hyaluronic acid alone (66 mg into each knee; group 2, treated with an injection of hyaluronic acid (49.5 mg plus diclofenac sodium (5 mg into each knee; group 3, treated with an injection of hyaluronic acid

  7. Exploring national surveillance for health-related workplace absenteeism: lessons learned from the 2009 influenza A pandemic.

    Science.gov (United States)

    Groenewold, Matthew R; Konicki, Doris L; Luckhaupt, Sara E; Gomaa, Ahmed; Koonin, Lisa M

    2013-04-01

    During the 2009 influenza A (H1N1) virus pandemic, the Centers for Disease Control and Prevention did a pilot study to test the feasibility of using national surveillance of workplace absenteeism to assess the pandemic's impact on the workplace to plan for preparedness and continuity of operations and to contribute to health awareness during the emergency response. Population-based and sentinel worksite approaches were used. Monthly measures of the 1-week prevalence of health-related absenteeism among full-time workers were estimated using nationally representative data from the Current Population Survey. Enhanced passive surveillance of absenteeism was conducted using weekly data from a convenience sample of sentinel worksites. Nationally, the pandemic's impact on workplace absenteeism was small. Estimates of 1-week absenteeism prevalence did not exceed 3.7%. However, peak workplace absenteeism was correlated with the highest occurrence of both influenza-like illness and influenza-positive laboratory tests. Systems for monitoring workplace absenteeism should be included in pandemic preparedness planning.

  8. Cost-related Nonadherence to Medication Treatment Plans: Native Hawaiian and Pacific Islander National Health Interview Survey, 2014.

    Science.gov (United States)

    McElfish, Pearl A; Long, Christopher R; Payakachat, Nalin; Felix, Holly; Bursac, Zoran; Rowland, Brett; Hudson, Jonell S; Narcisse, Marie-Rachelle

    2018-04-01

    Adherence to medication treatment plans is important for chronic disease (CD) management. Cost-related nonadherence (CRN) puts patients at risk for complications. Native Hawaiians and Pacific Islanders (NHPI) suffer from high rates of CD and socioeconomic disparities that could increase CRN behaviors. Examine factors related to CRN to medication treatment plans within an understudied population. Using 2014 NHPI-National Health Interview Survey data, we examined CRN among a nationally representative sample of NHPI adults. Bonferroni-adjusted Wald test and multivariable logistic regression were performed to examine associations among financial burden-related factors, CD status, and CRN. Across CD status, NHPI engaged in CRN behaviors had, on an average, increased levels of perceived financial stress, financial insecurity with health care, and food insecurity compared with adults in the total NHPI population. Regression analysis indicated perceived financial stress [adjusted odds ratio (AOR)=1.16; 95% confidence intervals (CI), 1.10-1.22], financial insecurity with health care (AOR=1.96; 95% CI, 1.32-2.90), and food insecurity (AOR=1.30; 95% CI, 1.06-1.61) all increase the odds of CRN among those with CD. We also found significant associations between perceived financial stress (AOR=1.15; 95% CI, 1.09-1.20), financial insecurity with health care (AOR=1.59; 95% CI, 1.19-2.12), and food insecurity (AOR=1.31; 95% CI, 1.04-1.65) and request for lower cost medication. This study demonstrated health-related and non-health-related financial burdens can influence CRN behaviors. It is important for health care providers to collect and use data about the social determinants of health to better inform their conversations about medication adherence and prevent CRN.

  9. Milk progesterone enzyme-linked immunosorbent assay as a tool to investigate ovarian cyclicity of water buffaloes in relation to body condition score and milk production

    Directory of Open Access Journals (Sweden)

    Banu Turgish A

    2012-05-01

    Full Text Available Abstract Background Application of assisted reproductive technologies in buffaloes is limited to some extent by farmers’ inability to detect oestrus because of its poor expression. The present study aimed at investigating reliability of a milk progesterone enzyme-linked immunosorbent assay (ELISA to assess the ovarian cyclicity during post partum, oestrus and post-breeding periods in water buffaloes. Methods Progesterone concentrations were measured by an ELISA in milk of 23 postpartum buffaloes in relation to oestrus, pregnancy, body condition score (BCS and milk production. Two milk samples were taken at 10 days intervals, every month starting from day 30 and continued to day 150 post partum. BCS and milk production were recorded during sample collection. Milk samples from bred buffaloes were collected at Day 0 (day of breeding, Days 10–12 and Days 22–24. Defatted milk was preserved at −80°C until analysis. Pregnancy was confirmed by palpation per rectum on Days 70–90. Results Seventeen buffaloes had 47 ovulatory cycles, one to four in each, 13 were detected in oestrus once (28 % oestrus detection rate. Progesterone concentration ≥1 ng/ml in one of the two 10-day-interval milk samples reflected ovulation and corpus luteum formation. The intervals between calving to first luteal activity and to first detected oestrus varied from 41 to 123 days (n = 17 and 83 to 135 (n = 13 days, respectively. Eight buffaloes were bred in the course of the study and seven were found pregnant. These buffaloes had a progesterone profile of low (P P  Conclusions Milk progesterone ELISA is a reliable tool for monitoring ovarian cyclicity and good BCS may be an indicator of resuming cyclicity in water buffalo.

  10. Milk progesterone enzyme-linked immunosorbent assay as a tool to investigate ovarian cyclicity of water buffaloes in relation to body condition score and milk production.

    Science.gov (United States)

    Banu, Turgish A; Shamsuddin, Mohammed; Bhattacharjee, Jayonta; Islam, Mohammad F; Khan, Saiful I; Ahmed, Jalal U

    2012-05-03

    Application of assisted reproductive technologies in buffaloes is limited to some extent by farmers' inability to detect oestrus because of its poor expression. The present study aimed at investigating reliability of a milk progesterone enzyme-linked immunosorbent assay (ELISA) to assess the ovarian cyclicity during post partum, oestrus and post-breeding periods in water buffaloes. Progesterone concentrations were measured by an ELISA in milk of 23 postpartum buffaloes in relation to oestrus, pregnancy, body condition score (BCS) and milk production. Two milk samples were taken at 10 days intervals, every month starting from day 30 and continued to day 150 post partum. BCS and milk production were recorded during sample collection. Milk samples from bred buffaloes were collected at Day 0 (day of breeding), Days 10-12 and Days 22-24. Defatted milk was preserved at -80°C until analysis. Pregnancy was confirmed by palpation per rectum on Days 70-90. Seventeen buffaloes had 47 ovulatory cycles, one to four in each, 13 were detected in oestrus once (28 % oestrus detection rate). Progesterone concentration ≥1 ng/ml in one of the two 10-day-interval milk samples reflected ovulation and corpus luteum formation. The intervals between calving to first luteal activity and to first detected oestrus varied from 41 to 123 days (n = 17) and 83 to 135 (n = 13) days, respectively. Eight buffaloes were bred in the course of the study and seven were found pregnant. These buffaloes had a progesterone profile of low (progesterone ELISA is a reliable tool for monitoring ovarian cyclicity and good BCS may be an indicator of resuming cyclicity in water buffalo.

  11. Sources of information about mental health and links to help seeking: findings from the 2007 Australian National Survey of Mental Health and Wellbeing.

    Science.gov (United States)

    Reavley, Nicola J; Cvetkovski, Stefan; Jorm, Anthony F

    2011-12-01

    The aim of this paper is to provide an analysis of data from the National Survey of Mental Health and Wellbeing (NSMHWB) on the factors associated with the use of sources of information on mental health. A further aim is to examine the associations between the use of information sources and professional help-seeking. Data from the 2007 NSMHWB were used. The survey sample comprised 8,841 residents of private dwellings across Australia aged 16-85 years. Television was the most common source of information about mental health issues in the previous 12 months (accessed by 20.5% of respondents) followed by pamphlets and brochures (accessed by 15.6% of respondents). Having an anxiety or affective disorder, female gender, higher levels of education and having a family member with a mental health problem was associated with the seeking of information on mental health issues from the internet, non-fiction books and brochures/pamphlets. Accessing information on the internet was associated with increased use of any mental health services, GPs and mental health professionals (MHPs). The results suggest that promotion of internet resources may offer the opportunity to increase help seeking for mental health problems and may offer the opportunity to engage those least likely to seek professional help, notably young males.

  12. A national drug related problems database: evaluation of use in practice, reliability and reproducibility

    DEFF Research Database (Denmark)

    Kjeldsen, Lene Juel; Birkholm, Trine; Fischer, Hanne Lis

    2014-01-01

    Background A drug related problems database (DRP-database) was developed on request by clinical pharmacists. The information from the DRP-database has only been used locally e.g. to identify focus areas and to communicate identified DRPs to the hospital wards. Hence the quality of the data...... by clinical pharmacists with categorization performed by the project group. Reproducibility was explored by re-categorization of a sample of existing records in the DRP-database by two project group members individually. Main outcome measures Observed proportion of agreement and Fleiss' kappa as measures...... reliability study of 34 clinical pharmacists showed high inter-rater reliability with the project group (Fleiss' kappa = 0.79 with 95 % CI (0.70; 0.88)), and the reproducibility study also documented high inter-rater reliability of a sample of 379 records from the DRP-database re-categorized by two project...

  13. Improved Formulations for Air-Surface Exchanges Related to National Security Needs: Dry Deposition Models

    Energy Technology Data Exchange (ETDEWEB)

    Droppo, James G.

    2006-07-01

    The Department of Homeland Security and others rely on results from atmospheric dispersion models for threat evaluation, event management, and post-event analyses. The ability to simulate dry deposition rates is a crucial part of our emergency preparedness capabilities. Deposited materials pose potential hazards from radioactive shine, inhalation, and ingestion pathways. A reliable characterization of these potential exposures is critical for management and mitigation of these hazards. A review of the current status of dry deposition formulations used in these atmospheric dispersion models was conducted. The formulations for dry deposition of particulate materials from am event such as a radiological attack involving a Radiological Detonation Device (RDD) is considered. The results of this effort are applicable to current emergency preparedness capabilities such as are deployed in the Interagency Modeling and Atmospheric Assessment Center (IMAAC), other similar national/regional emergency response systems, and standalone emergency response models. The review concludes that dry deposition formulations need to consider the full range of particle sizes including: 1) the accumulation mode range (0.1 to 1 micron diameter) and its minimum in deposition velocity, 2) smaller particles (less than .01 micron diameter) deposited mainly by molecular diffusion, 3) 10 to 50 micron diameter particles deposited mainly by impaction and gravitational settling, and 4) larger particles (greater than 100 micron diameter) deposited mainly by gravitational settling. The effects of the local turbulence intensity, particle characteristics, and surface element properties must also be addressed in the formulations. Specific areas for improvements in the dry deposition formulations are 1) capability of simulating near-field dry deposition patterns, 2) capability of addressing the full range of potential particle properties, 3) incorporation of particle surface retention/rebound processes, and

  14. Why Is Health Literacy Related to Health? An Exploration among U.S. National Assessment of Adult Literacy Participants 40 Years of Age and Older

    Science.gov (United States)

    Ownby, Raymond L.; Waldrop-Valverde, Drenna; Taha, Jessica

    2012-01-01

    Health literacy has emerged as an important factor related to health in older persons. The reason for the link between health literacy and health outcomes is not clear. Possible explanations include common relations among income, education, access to health care, health-promotion behaviors, frequency of reading, and perceptual impairments. In this…

  15. Cold Climate Related Structural Sinks Accommodate Unusual Soil Constituents, Pinelands National Reserve, New Jersey, USA

    Science.gov (United States)

    Demitroff, M.; Lecompte, M. A.; Rock, B. N.

    2009-12-01

    Firestone and others proposed an extraterrestrial (ET) impact upon the Laurentide Ice Sheet 12,900 years ago led to abrupt climate change and left behind a distinct suite of microscopic soil markers. If so, then soil memory of such an extreme event should be apparent across a wide swath of ice-marginal North America. New Jersey’s Pine Barrens has a remarkably well-preserved record of Late Pleistocene soil structures that provide snapshots of rigorous climatic episodes, the youngest of which are potential reservoirs for ET markers. Cryogenic macrostructures are fissures related to episodic temperature and moisture extremes providing excellent chronostratigraphic control - unlike soil horizons that are often affected by denudation and pedogenic modification. Three distinct ground structures were sampled for evidence of infill-related ET markers: 1) two ground (soil) wedges (early Holocene?); 2) a younger sand-wedge cast (late-Wisconsinan?); and 3) an older sand-wedge cast (early-Wisconsinan?). Attendant host sediment and capping colluvium coversand samples were also collected for evidence of ET markers to detect potential source sinks. Our pedocomplex contained elements ranging from Miocene Cohansey Formation basement sands to early-Holocene fluvioeolian coversands. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive x-ray analysis (EDX) are being used to characterize soil constituents of interest. Carbon and luminescence dating are underway to provide geomorphic events timing associated with specific soil constituent trap formation. Fly ash collected from a coal-fired electrical plant 13-km distant was also examined. Several soil constituents atypical to the local petrology as currently understood were found. Infill from two ground (soil) wedges contained ~100,000 to ~500,000 magnetic spherules/kg, 25 to 50 translucent amber-colored spherules/kg, 250 to 500 carbon spherules/kg, charcoal, and pieces of glass-like carbon

  16. Asbestos and Asbestos-related Diseases in Vietnam: In reference to the International Labor Organization/World Health Organization National Asbestos Profile

    Directory of Open Access Journals (Sweden)

    Van Hai Pham

    2013-06-01

    Full Text Available This paper describes progress on formulating a national asbestos profile for the country of Vietnam. The Center of Asbestos Resource, Vietnam, formulated a National Profile on Asbestos-related Occupational Health, with due reference to the International Labor Organization/World Health Organization National Asbestos Profile. The Center of Asbestos Resource was established by the Vietnamese Health Environment Management Agency and the National Institute of Labor Protection, with the support of the Australian Agency for International Development, as a coordinating point for asbestos-related issues in Vietnam. Under the National Profile on Asbestos-related Occupational Health framework, the Center of Asbestos Resource succeeded in compiling relevant information for 15 of the 18 designated items outlined in the International Labor Organization/World Health Organization National Asbestos Profile, some overlaps of the information items notwithstanding. Today, Vietnam continues to import and use an average of more than 60,000 metric tons of raw asbestos per year. Information on asbestos-related diseases is limited, but the country has begun to diagnose mesothelioma cases, with the technical cooperation of Japan. As it stands, the National Profile on Asbestos-related Occupational Health needs further work and updating. However, we envisage that the National Profile on Asbestos-related Occupational Health will ultimately facilitate the smooth transition to an asbestos-free Vietnam.

  17. Estimating internal exposure risks by the relative risk and the National Institute of Health risk models

    International Nuclear Information System (INIS)

    Mehta, S.K.; Sarangapani, R.

    1995-01-01

    This paper presents tabulations of risk (R) and person-years of life lost (PYLL) for acute exposures of individual organs at ages 20 and 40 yrs for the Indian and Japanese populations to illustrate the effect of age at exposure in the two models. Results are also presented for the organ wise nominal probability coefficients (NPC) and PYLL for individual organs for the age distributed Indian population by the two models. The results presented show that for all organs the estimates of PYLL and NPC for the Indian population are lower than those for the Japanese population by both models except for oesophagus, breast and ovary by the relative risk (RR) model, where the opposite trend is observed. The results also show that the Indian all-cancer values of NPC averaged over the two models is 2.9 x 10 -2 Sv -1 , significantly lower than the world average value of 5x10 -2 Sv -1 estimated by the ICRP. (author). 9 refs., 2 figs., 2 tabs

  18. Clinical Characteristics of Fatal Methamphetamine-related Stroke: A National Study.

    Science.gov (United States)

    Darke, Shane; Lappin, Julia; Kaye, Sharlene; Duflou, Johan

    2018-05-01

    The study aimed to determine the clinical characteristics of fatal methamphetamine-related stroke in Australia, 2009-2015. There were 38 cases, 60.5% male, with a mean age of 40.3 years. In no case was there evidence that this was the first time methamphetamine had been used by the decedent, and 52.6% had known histories of injecting drug use. The stroke was hemorrhagic in 37 of 38 cases. In 21.1% of cases, the stroke was purely parenchymal and, in 18.4%, involved purely the subarachnoid space. A ruptured berry aneurysm was present in 31.6% and in 68.8% of initial subarachnoid hemorrhages. There was evidence of systemic hypertension in 8 of 25 cases in which full autopsy findings were available. With increased use of methamphetamine, there is a high probability of increased hemorrhagic stroke incidence among young people. In cases of fatal hemorrhagic stroke among young cases presenting to autopsy, the possibility of methamphetamine use should be borne in mind. © 2017 American Academy of Forensic Sciences.

  19. Activities of the National Academy of Sciences in relation to the Radiation Effects Research Foundation

    Energy Technology Data Exchange (ETDEWEB)

    Edington, C.W.

    1992-06-01

    This progress report relates progress in the various research projects evaluating the late health effects, both somatic and genetic, resulting from radiation exposure of the survivors of the atomic bombs at Hiroshima and Nagasaki, Japan. Considerable progress has been made in the collection and utilization of the various epidemiological data bases. These include the Life Span Study, (LSS) cohort, the Adult Health Study (AHS) cohort, the In Utero cohort, the leukemia registry and the F-1 Study population. Important progress has been made in using RERF Tumor and Tissue Registry records for evaluation of cancer incidence and radiation risk estimates for comparison with cancer mortality and risk in the LSS cohort. At the present time, a manuscript on the incidence of solid tumors (1950-1987) is undergoing internal and external review for publication as an RERF Technical report (TR) and for publication in a peer-reviewed scientific journal. In addition, manuscripts are in preparation on (1) a comprehensive report on the incidence of hematological cancers, including analysis of leukemia by cell type (1950-1987), (2) a general description of Tumor Registry operations and (3) a comparison of incidence- and mortality-based estimates of radiation risk in the LSS cohort.

  20. Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases

    Directory of Open Access Journals (Sweden)

    Hawkes Corinna

    2006-03-01

    Full Text Available Abstract In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related chronic diseases worldwide, is rooted in the processes of globalization. Globalization affects the nature of agri-food systems, thereby altering the quantity, type, cost and desirability of foods available for consumption. Understanding the links between globalization and the nutrition transition is therefore necessary to help policy makers develop policies, including food policies, for addressing the global burden of chronic disease. While the subject has been much discussed, tracing the specific pathways between globalization and dietary change remains a challenge. To help address this challenge, this paper explores how one of the central mechanisms of globalization, the integration of the global marketplace, is affecting the specific diet patterns. Focusing on middle-income countries, it highlights the importance of three major processes of market integration: (I production and trade of agricultural goods; (II foreign direct investment in food processing and retailing; and (III global food advertising and promotion. The paper reveals how specific policies implemented to advance the globalization agenda account in part for some recent trends in the global diet. Agricultural production and trade policies have enabled more vegetable oil consumption; policies on foreign direct investment have facilitated higher consumption of highly-processed foods, as has global food marketing. These dietary outcomes also reflect the socioeconomic and cultural context in which these policies are operating. An important finding is that the dynamic, competitive forces unleashed as a result of global market integration facilitates not only convergence in consumption habits (as is commonly assumed in the "Coca-Colonization" hypothesis, but adaptation to

  1. Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases

    Science.gov (United States)

    Hawkes, Corinna

    2006-01-01

    In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related chronic diseases worldwide, is rooted in the processes of globalization. Globalization affects the nature of agri-food systems, thereby altering the quantity, type, cost and desirability of foods available for consumption. Understanding the links between globalization and the nutrition transition is therefore necessary to help policy makers develop policies, including food policies, for addressing the global burden of chronic disease. While the subject has been much discussed, tracing the specific pathways between globalization and dietary change remains a challenge. To help address this challenge, this paper explores how one of the central mechanisms of globalization, the integration of the global marketplace, is affecting the specific diet patterns. Focusing on middle-income countries, it highlights the importance of three major processes of market integration: (I) production and trade of agricultural goods; (II) foreign direct investment in food processing and retailing; and (III) global food advertising and promotion. The paper reveals how specific policies implemented to advance the globalization agenda account in part for some recent trends in the global diet. Agricultural production and trade policies have enabled more vegetable oil consumption; policies on foreign direct investment have facilitated higher consumption of highly-processed foods, as has global food marketing. These dietary outcomes also reflect the socioeconomic and cultural context in which these policies are operating. An important finding is that the dynamic, competitive forces unleashed as a result of global market integration facilitates not only convergence in consumption habits (as is commonly assumed in the "Coca-Colonization" hypothesis), but adaptation to products targeted at different

  2. The Age-Related Macular Degeneration Complex: Linking Epidemiology and Histopathology Using the Minnesota Grading System (The Inaugural Frederick C. Blodi Lecture).

    Science.gov (United States)

    Olsen, Timothy W; Bottini, Alexander R; Mendoza, Pia; Grossniklausk, Hans E

    2015-09-01

    To describe the histopathologic findings of the four stages of age-related macular degeneration (AMD) as defined by the Age-Related Eye Disease Study (AREDS) using the Minnesota grading system (MGS). There are no animal models for AMD. Eye banks enable access to human tissue with AMD. The level of AMD (grades 1 through 4) as defined by AREDS is determined ex vivo using the MGS. The AREDS has the largest collection to date of prospectively gathered data on the natural history of AMD. Since the MGS uses the same clinical criteria as AREDS, the addition of histopathologic findings of graded tissue confirms important pathophysiology at each stage of AMD. Four eye bank eyes were graded according to the MGS. Only the right eyes were dissected for phenotype grading. The fellow (left) eyes were fixed for histopathologic study. The eyes were serially sectioned (7 μm) through the macula. Individual slides were examined, and a two-dimensional reconstruction of the topography of the macula was created for each donor. Selected, unstained slides were used for immunohistochemical staining. In one donor, portions of tissue were obtained for transmission electron microscopic (TEM) processing. Donor 1 had a rare hard, nodular druse (MGS1). Donor 2 had intermediate confluent drusen (MGS2). Donor 3 had numerous intermediate drusen (MGS3) in the right eye. Histopathology of the fellow left showed basal laminar deposits (BLamD), soft drusen, and an area of occult choroidal neovascularization underlying the retinal pigment epithelium (RPE) with endothelial cells (CD31-positive). Donor 4 also had MGS 3 along with reticular pseudodrusen (RPD). Histologic and TEM examination demonstrated diffuse BLamD, thickening of Bruch's membrane, hard drusen, and focal nodules underlying the RPE that corresponded to the RPD. EM examination demonstrated both BLamD and electron-dense material located just external to the elastic layer of Bruch's membrane. Eye bank eyes graded using the MGS serve as an

  3. Comorbidity of social anxiety disorder and antisocial personality disorder in the National Epidemiological Survey on Alcohol and Related Conditions (NESARC).

    Science.gov (United States)

    Galbraith, Todd; Heimberg, Richard G; Wang, Shuai; Schneier, Franklin R; Blanco, Carlos

    2014-01-01

    Social anxiety disorder (SAD) and antisocial personality disorder (ASPD) are not often thought of as being comorbid. However, recent research suggests the existence of a SAD subtype with characteristics atypical of SAD but common to ASPD. Thus, we explored two competing hypotheses: (1) SAD and ASPD represent opposite ends of a single dimension, or (2) SAD and ASPD exist on two separate dimensions that may be positively correlated. Data were obtained from the National Epidemiological Survey on Alcohol and Related Conditions. SAD-ASPD was related to greater impairment and psychiatric comorbidity than either disorder alone. The SAD-ASPD group was also more likely to seek treatment for their SAD symptoms and to drink before/during antisocial acts than the SAD only group. The presence of SAD for individuals with ASPD (and vice versa) does not appear to provide any "protective benefits." SAD and ASPD appear to be two separate but correlated disorders. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. An overview of intravenous-related medication administration errors as reported to MEDMARX, a national medication error-reporting program.

    Science.gov (United States)

    Hicks, Rodney W; Becker, Shawn C

    2006-01-01

    Medication errors can be harmful, especially if they involve the intravenous (IV) route of administration. A mixed-methodology study using a 5-year review of 73,769 IV-related medication errors from a national medication error reporting program indicates that between 3% and 5% of these errors were harmful. The leading type of error was omission, and the leading cause of error involved clinician performance deficit. Using content analysis, three themes-product shortage, calculation errors, and tubing interconnectivity-emerge and appear to predispose patients to harm. Nurses often participate in IV therapy, and these findings have implications for practice and patient safety. Voluntary medication error-reporting programs afford an opportunity to improve patient care and to further understanding about the nature of IV-related medication errors.

  5. Self-rated health in relation to rape and mental health disorders in a national sample of college women.

    Science.gov (United States)

    Zinzow, Heidi M; Amstadter, Ananda B; McCauley, Jenna L; Ruggiero, Kenneth J; Resnick, Heidi S; Kilpatrick, Dean G

    2011-01-01

    The purpose of this study was to employ a multivariate approach to examine the correlates of self-rated health in a college sample of women, with particular emphasis on sexual assault history and related mental health outcomes. A national sample of 2,000 female college students participated in a structured phone interview between January and June 2006. Interview modules assessed demographics, posttraumatic stress disorder, major depressive episode, substance use, rape experiences, and physical health. Logistic regression analyses showed that poor self-rated health was associated with low income (odds ratio [OR] = 2.70), lifetime posttraumatic stress disorder (OR = 2.47), lifetime major depressive episode (OR = 2.56), past year illicit drug use (OR = 2.48), and multiple rape history (OR = 2.25). These findings highlight the need for university mental health and medical service providers to assess for rape history, and to diagnose and treat related psychiatric problems in order to reduce physical morbidity.

  6. Comorbidity of Social Anxiety Disorder and Antisocial Personality Disorder in the National Epidemiological Survey on Alcohol and Related Conditions (NESARC)

    Science.gov (United States)

    Galbraith, Todd; Heimberg, Richard G.; Wang, Shuai; Schneier, Franklin R.; Blanco, Carlos

    2013-01-01

    Social anxiety disorder (SAD) and antisocial personality disorder (ASPD) are not often thought of as being comorbid. However, recent research suggests the existence of a SAD subtype with characteristics atypical of SAD but common to ASPD. Thus, we explored two competing hypotheses: 1) SAD and ASPD represent opposite ends of a single dimension, or 2) SAD and ASPD exist on two separate dimensions that may be positively correlated. Data were obtained from the National Epidemiological Survey on Alcohol and Related Conditions. SAD-ASPD was related to greater impairment and psychiatric comorbidity than either disorder alone. The SAD-ASPD group was also more likely to seek treatment for their SAD symptoms and to drink before/during antisocial acts than the SAD only group. The presence of SAD for individuals with ASPD (and vice versa) does not appear to provide any “protective benefits.” SAD and ASPD appear to be two separate but correlated disorders. PMID:24384071

  7. The longitudinal relation between peer violent victimization and delinquency: results from a national representative sample of u.s. Adolescents.

    Science.gov (United States)

    Jackson, Corrie L; Hanson, Rochelle F; Amstadter, Ananda B; Saunders, Benjamin E; Kilpatrick, Dean G

    2013-05-01

    Using a nationally representative sample of adolescents from the United States aged 12 to 17 years (Wave 1, n = 3,614; Wave 2, n = 2,511), this study examined (a) demographic and descriptive information about peer violent victimization (PVV); and (b) the longitudinal relation between a history of PVV and delinquency. Results indicated that 12.4% of adolescents reported lifetime exposure to PVV, and many of these adolescents with a previous history of PVV also reported exposure to other forms of interpersonal violence, with witnessing community/school violence being the most commonly endorsed exposure category. Males, older adolescents, African American adolescents, and adolescents from low-income households were significantly more likely to endorse PVV. Regardless of the victim's gender, the majority of the perpetrators were male. After controlling for exposure to other forms of interpersonal violence and a history of delinquency, PVV was related to subsequent delinquency. Implications for policy, practice, and future research are discussed.

  8. Evidence of increased STI/HIV-related risk behavior among male perpetrators of intimate partner violence in Guatemala: results from a national survey.

    Science.gov (United States)

    Hembling, John; Andrinopoulos, Katherine

    2014-01-01

    Intimate partner violence (IPV) is a significant public health problem with a demonstrated link to increased sexually transmitted infection (STI)/HIV-related risk and vulnerability. While IPV is an important issue in Central America, the link to STI/HIV risk has not been explored in this region. In this study, the relationship between emotional and physical/sexual IPV and the STI/HIV-related risk behaviors of sex worker patronage and infidelity is assessed among male IPV perpetrators using data from a national survey conducted in 2009 in Guatemala (n = 4773 married/partnered men). Bivariate associations between background characteristics and emotional and physical IPV perpetration were explored. Logistic regression models were run to test associations between IPV for each sexual risk behavior. Perpetration of emotional and physical/sexual IPV was more common among married/partnered men who were older than 24, had more education, lived in urban areas, or were in common law versus married unions. Reports of past-year emotional IPV perpetration increased as wealth quintile increased. After adjusting for demographics and other characteristics, physical/sexual IPV perpetration was associated with past-year infidelity (AOR 1.9, 95% CI: 1.1-3.6). Lifetime emotional IPV (AOR 1.4, 95% CI: 1.1-1.7) and physical/sexual IPV 1.6 (95% CI 1.2-2.0) were positively associated with a history of sex worker patronage. Endorsement of traditional gender role norms showed a marginally positive association with past-year infidelity in the adjusted model (AOR 1.3, 95% CI 1.0-1.8). The study findings from Guatemala reinforce the growing evidence globally that male IPV perpetrators are more likely to engage in risky sexual behavior, including sex worker patronage and main partner infidelity. The concurrency of violence and increased STI/HIV risk may compound the health risks for female victims of IPV who also face injury and psychological trauma. Integration of prevention and screening of

  9. Weight-related behaviors among non-overweight adolescents: results from the Korean national survey from 2005 to 2007.

    Science.gov (United States)

    Lee, Kayoung

    2012-01-01

    This study aimed to assess the prevalence of overweight misperception, unhealthy diet practices, and factors associated with these weight-related behaviors among Korean adolescents. The subjects were a nationally representative sample of non-overweight students (52,515 in 2005, 64,084 in 2006, and 67,113 in 2007) in middle and high schools who completed the Korea Youth Risk Behavior Web-Based Survey. The prevalence of weight-related behaviors and factors associated with these behaviors were assessed using a complex sampling design. Of non-overweight students, 14.9% of boys and 22.2% of girls reported their weight as overweight/obese. Dieting within the last year was reported by 19.8% of boys and 41.8% of girls. Of those who attempted dieting, 17.1% of boys and 24.6% of girls indicated practicing at least one unhealthy diet behavior within the last month. Overweight misperceptions were independently associated with diet attempts and unhealthy diets after adjustment for weight status, and demographic, social, and psychological factors. Additionally, these weight-related behaviors were also associated with psychosocial factors such as low school achievement, sadness, suicidal ideation, increased stress perception, and cigarette or alcohol use. In conclusion, the high prevalence of inappropriate weight-related behaviors suggests a need for comprehensive approaches to improve weight-related behaviors in non-overweight Korean adolescents.

  10. CONTEMPORARY ISSUES RELATED TO ILLICIT DRUG TRAFFICKING AND CONSUMPTION TARGETING THE NATIONAL SECURITY OF ROMANIA

    Directory of Open Access Journals (Sweden)

    Bogdan MARINESCU

    2018-05-01

    Full Text Available A serious social problem is drug use, which is very widespread all over the world. Drugs are a terrible problem whose seriousness becomes more visible every day. Problems caused by drug abuse and illegal trafficking are among the most serious problems faced by the world today but also threatening future generations. After the First World War, drugs began to be consumed on a large scale. Up to the end of the 30s, they were legal. Their marketing over time has led to enormous profits outlaw, making drugs an invaluable source for the black market. Scourge illicit drug trafficking from South America and the Middle East comprised the whole the planet. Governments have begun to allocate more resources to the fight against drugs, but the processes were slow because the problem was very complex. The impact was very high among young people who out of curiosity, terrible or solidarity with the entourage, have begun to consume. The Romanian society was caught by surprise by this drug scourge, coming out so very serious problems both in justice and in the medical world. Weak reactions and untrained authorities have favored the phenomenon of drug abuse that has come to be devastating. Drug use is a high-risk activity. Optimism and illusion of maintaining self-control is also dangerous because it affects reasoning. The drug consumer becomes not only an unfortunate person, but also a social problem. Changes made by traffickers are evident in street-related lawsuits: thefts, arsonists, assassinations. We are all affected in some way by drug trafficking. The extent of the problem current narcotics outweighs the concerns of the police forces and the medical world, constituting a threat to the economic and social order of the world.

  11. Epidemiology of DSM-5 bipolar I disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions - III.

    Science.gov (United States)

    Blanco, Carlos; Compton, Wilson M; Saha, Tulshi D; Goldstein, Benjamin I; Ruan, W June; Huang, Boji; Grant, Bridget F

    2017-01-01

    The objective of this study was to present 12-month and lifetime prevalence, correlates, comorbidity, treatment and disability of DSM-5 bipolar I disorder. Nationally representative U.S. adult sample (N = 36,309), the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions - III. Prevalences of 12-month and lifetime DSM-5 bipolar I disorder were 1.5% and 2.1% and did not differ between men (1.6% and 2.2%) and women (1.5% and 2.0%). Prevalences of bipolar I disorder were greater among Native Americans, and lower among Blacks, Hispanics and Asians/Pacific Islanders than whites. Rates were also lower among younger than older individuals, those previously married than currently married and with lower education and income relative to higher education and income. Bipolar I disorder was more strongly related to borderline and schizotypal personality disorders (adjusted odds ratios (AORS) = 2.2-4.7)), than to anxiety disorders (AORs = 1.3-2.9), and substance use disorders (AORs = 1.3-2.1) overall and among men and women. Quality of life was lower among individuals with bipolar I disorder relative to those without the disorder. Treatment rates among individuals with bipolar I disorder were low in the total sample (46%, SE = 2.63), among men (36.7%, SE = 3.82) and among women (55.8%, SE = 3.32). Bipolar I disorder continues to be common disabling and highly comorbid disorder among men and women, contributing substantially to low quality of life and burden of disease in our society. Copyright © 2016. Published by Elsevier Ltd.

  12. Evaluation of drinking patterns and their impact on alcohol-related aggression: a national survey of adolescent behaviours.

    Science.gov (United States)

    Siciliano, Valeria; Mezzasalma, Lorena; Lorenzoni, Valentina; Pieroni, Stefania; Molinaro, Sabrina

    2013-10-10

    Although there have been a wide range of epidemiological studies examining the impact of patterns of alcohol consumption among adolescents, there remains considerable variability in both defining these patterns and the ability to comprehensively evaluate their relationship to behavioural patterns. This study explores a new procedure for defining and evaluating drinking patterns and integrating well-established indicators. The composite measure is then used to estimate the impact of these patterns on alcohol-related aggressive behaviour among Italian adolescents. Data were collected as part of the 2011 European School Survey Project on Alcohol and other Drugs (ESPAD). A national sample of 14,199 students aged 15-19 years was collected using an anonymous, self-administered questionnaire completed in a classroom setting. Drinking patterns were established using principal component analysis. Alcohol-related aggression was analysed as to its relationship to patterns of drinking, behaviour of friends towards alcohol use, substance use/abuse, school performance, family relationships and leisure activities. Several specific drinking patterns were identified: "Drinking to Excess" (DE), "Drinking with Intoxication" (DI) and "Drinking but Not to Excess" (DNE). A higher percentage of males were involved in alcohol-related aggression compared with females. In males, the DE and DI patterns significantly increased the likelihood of alcohol-related aggression, whereas the DNE pattern was negatively associated. Similar results were found in females, although the DI pattern was not significantly associated with alcohol-related aggression. Overall, cigarette smoking, illegal drug use, truancy, limited parental monitoring, frequent evenings spent outside of the home and peer influence associated strongly with alcohol-related aggression. Our findings suggest that drinking patterns, as uniquely monitored with an integrated metric, can: 1) explain drinking habits better than commonly

  13. Associations of breakfast skipping with obesity and health-related quality of life: evidence from a national survey in Taiwan.

    Science.gov (United States)

    Huang, C-J; Hu, H-T; Fan, Y-C; Liao, Y-M; Tsai, P-S

    2010-04-01

    This study investigated the associations of breakfast skipping with obesity and health-related quality of life (QOL). We also tested the hypothesis that there is a dose-dependent relationship between frequency of breakfast consumption and prevalence of obesity. This cross-section study used a national representative sample (n=15 340) from the 2005 Taiwan National Health Interview Survey. Breakfast skippers were defined as those who ate breakfast about once a week or less often and those who never ate breakfast. Individuals were classified as 'obese' if their body mass index was >or=27. Health-related QOL was assessed using the Medical Outcome Studies 36-Item Short-Form (SF-36) Health Survey. Logistic regression was used to examine the odds ratio of obesity and associated 95% confidence intervals (CIs) in breakfast skippers compared with breakfast eaters. Multivariable logistic regression modeling was used to adjust all risk estimates for covariates. The unadjusted odds ratio of obesity in breakfast skippers was 1.23 (95% CI: 1.06, 1.43). The odds of developing obesity for breakfast skippers was 1.34 (95% CI: 1.15, 1.56) controlling for age, sex, marital status, educational level, monthly income, smoking, alcohol, betel nut chewing and exercise habit. The Cochran-Armitage trend test revealed that the prevalence rate of obesity decreased as the frequency of breakfast consumption increased (P=0.005). Breakfast skippers had significantly worse health-related QOL than breakfast eaters (Pbreakfast skippers had significantly lower scores in 5 out of 8 domain scores of the SF-36, namely general health perceptions (Pmental health (Pbreakfast eating in obesity prevention.

  14. The Transformation of Teaching Habits in Relation to the Introduction of Grading and National Testing in Science Education in Sweden

    Science.gov (United States)

    Lidar, Malena; Lundqvist, Eva; Ryder, Jim; Östman, Leif

    2017-12-01

    In Sweden, a new curriculum and new methods of assessment (grading of students and national tests) in science education were introduced in grade 6 in 2012/2013. We have investigated what implications these reforms have for teachers' teaching and assessment practices in order to explore the question of how teachers transform their teaching habits in relation to policy reforms. Interviews with 16 teachers teaching science in grade 6 (Y6), over 3 years after the reforms were introduced, were analysed. Building on the ideas of John Dewey, we consider teachers' talk about their everyday practice as expressions of their habits of teaching. Habits of teaching are related both to individual experiences as well as institutional traditions in and about teaching. A categorisation of educational philosophies was used to teachers' habits of teaching to a collective level and to show how habits can be transformed and developed over time in specific sociocultural contexts. The teachers were categorised as using essentialist and/or progressivist educational philosophy. In the responses to the introduction of grading and national testing, the teachers took three approaches: Their habits being reinforced, revised or unchanged in relation to the reforms. Although the responses were different, a striking similarity was that all teachers justified their responses with wanting to do what is best for students. However, how to show care for students differed, from delivering scientific knowledge in alignment with an essentialist educational philosophy, to preparing students to do well on tests, to supporting their development as individuals, which is in alignment with a progressivist educational philosophy.

  15. The impact of cessation media messages on cessation-related outcomes: results from a national experiment of smokers.

    Science.gov (United States)

    Duke, Jennifer C; Nonnemaker, James M; Davis, Kevin C; Watson, Kimberly A; Farrelly, Matthew C

    2014-01-01

    Examine effects of exposure to two types of cessation advertisements on changes in cessation-related outcomes. Experimental data from a nationally representative, longitudinal sample of smokers, collected in three waves over 4 weeks. National. Subjects. Three thousand and two adult U.S. smokers aged 18+ completed baseline and follow-up interviews at 2 and 4 weeks, from December 2010 to February 2011. Six randomly assigned conditions consisting of repeated exposure to cessation advertisements: why-to-quit advertisements featuring emotional, personal testimonies (1: WTQ-T) or graphic images (2: WTQ-G); how-to-quit advertisements (3: HTQ), a combination of both (4: WTQ-T + HTQ; 5: WTQ-G + HTQ), and no-ad condition (6: control). Cessation-related beliefs, attitudes, intentions, and quitting behavior. Multivariable ordinary least squares and logistic regressions testing whether exposure to antitobacco television advertisements were associated with changes in tobacco-related outcomes. Exposure to WTQ-T or WTQ-G advertisements, both alone and combined with HTQ advertisements, elicited positive change in beliefs, attitudes, and intentions as compared to controls. Smokers in three of four WTQ conditions were substantially more likely to have quit smoking at 4 weeks than controls (odds ratios range from 5.9 to 10.1, p advertisements markedly increases the odds that a smoker will quit in the study period, suggesting positive movement toward successful, long-term cessation. HTQ advertisements did not enhance advertising effectiveness and may not be suitable as a primary message strategy.

  16. Game Related Statistics Discriminating Between Starters and Nonstarters Players in Women’S National Basketball Association League (WNBA)

    Science.gov (United States)

    Gòmez, Miguel-Ángel; Lorenzo, Alberto; Ortega, Enrique; Sampaio, Jaime; Ibàñez, Sergio-José

    2009-01-01

    The aim of the present study was to identify the game-related statistics that allow discriminating between starters and nonstarter players in women’s basketball when related to winning or losing games and best or worst teams. The sample comprised all 216 regular season games from the 2005 Women’s National Basketball Association League (WNBA). The game-related statistics included were 2- and 3- point field-goals (both successful and unsuccessful), free-throws (both successful and unsuccessful), defensive and offensive rebounds, assists, blocks, fouls, steals, turnovers and minutes played. Results from multivariate analysis showed that when best teams won, the discriminant game-related statistics were successful 2-point field-goals (SC = 0.47), successful free-throws (SC = 0.44), fouls (SC = -0.41), assists (SC = 0.37), and defensive rebounds (SC = 0.37). When the worst teams won, the discriminant game-related statistics were successful 2-point field- goals (SC = 0.37), successful free-throws (SC = 0.45), assists (SC = 0.58), and steals (SC = 0.35). The results showed that the successful 2-point field-goals, successful free-throws and the assists were the most powerful variables discriminating between starters and nonstarters. These specific characteristics helped to point out the importance of starters’ players shooting and passing ability during competitions. Key points The players’ game-related statistical profile varied according to team status, game outcome and team quality in women’s basketball. The results of this work help to point out the different player’s performance described in women’s basketball compared with men’s basketball. The results obtained enhance the importance of starters and nonstarters contribution to team’s performance in different game contexts. Results showed the power of successful 2-point field-goals, successful free-throws and assists discriminating between starters and nonstarters in all the analyses. PMID:24149538

  17. Major Links.

    Science.gov (United States)

    Henderson, Tona

    1995-01-01

    Provides electronic mail addresses for resources and discussion groups related to the following academic majors: art, biology, business, chemistry, computer science, economics, health sciences, history, literature, math, music, philosophy, political science, psychology, sociology, and theater. (AEF)

  18. Pedagogical Staff in Children's Day Care Centres in Germany--Links between Working Conditions, Job Satisfaction, Commitment and Work-Related Stress

    Science.gov (United States)

    Schreyer, Inge; Krause, Martin

    2016-01-01

    This article investigates links between staff working conditions in children's day care centres ("Kindertageseinrichtungen"--known as "Kitas" in Germany), job satisfaction, commitment and perceived stress at work. Data are based on the nationwide, representative questionnaire survey AQUA ("Arbeitsplatz und Qualität in…

  19. Cerebral, cerebellar, and colobomatous anomalies in three related males: Sex-linked inheritance in a newly recognized syndrome with features overlapping with Joubert syndrome

    NARCIS (Netherlands)

    Kroes, Hester Y.; Nievelstein, Rutger-Jan A. J.; Barth, Peter G.; Nikkels, Peter G. J.; Bergmann, Carsten; Gooskens, Rob H. J. M.; Visser, Gepke; van Amstel, Hans-Kristian Ploos; Beemer, Frits A.

    2005-01-01

    We present a so far unrecognized X-linked mental retardation syndrome with features overlapping with Joubert syndrome (JBS). Two brothers showed hypotonia, mental retardation, ocular abnormalities with impaired vision and colobomas and a breathing pattern compatible with JBS. Neuroimaging revealed

  20. C2 Link Security for UAS: Technical Literature Study and Preliminary Functional Requirements. Version 0.9 (Working Draft)

    Science.gov (United States)

    2005-01-01

    This document provides a study of the technical literature related to Command and Control (C2) link security for Unmanned Aircraft Systems (UAS) for operation in the National Airspace System (NAS). Included is a preliminary set of functional requirements for C2 link security.

  1. 50 CFR 36.33 - What do I need to know about using cabins and related structures on Alaska National Wildlife...

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false What do I need to know about using cabins and related structures on Alaska National Wildlife Refuges? 36.33 Section 36.33 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE...

  2. How did national life expectation related to school years in developing countries - an approach using panel data mining.

    Science.gov (United States)

    Jian, Wen-Shan; Huang, Chen-Ling; Iqbal, Usman; Nguyen, Phung-Anh; Hsiao, George; Li, Hsien-Chang

    2014-03-01

    The purpose of the study was to probe into the changes in life expectancy associated with schooling years found by the Organization for Economic Co-operation and Development (OECD). The study was based on the OECD database from the period 2000 to 2006. The data of thirty countries were constructed to allow comparisons over time and across these countries. Panel data analysis was used to estimate the relationship of national education, as defined as school years, with life expectancy. The control factors considered were numbers of practicing physicians, practicing nurses, hospital beds, and GDP. We used fixed effects of both country and time through linear regression, the coefficient of school years in relation to life expectancy was statistically significant but negative. This finding is not in accord with the hypothesis that investing in human capital through education stimulates better health outcomes. Within developing countries, educational attainment is no longer keeping the same pace with life expectancy as before. Therefore, we suggest that an effective education policy should cover diverse topics, for example, balancing economic growth and mental hygiene, to improve national life expectancy. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  3. Patterns of Alcohol Consumption and Related Behaviors in Brazil: Evidence from the 2013 National Health Survey (PNS 2013.

    Directory of Open Access Journals (Sweden)

    James Macinko

    Full Text Available This study uses data from a nationally representative household survey (the 2013 National Health Survey, n = 62,986 to describe patterns of alcohol consumption and related behaviors among Brazilian adults. Analyses include descriptive and multivariable Poisson regression for self-reports in the past 30 days of: drinking any alcohol, binge drinking, binge drinking 4 or more times, and driving after drinking (DD; as well as age of alcohol consumption initiation. Results show that current drinking prevalence was 26%, with an average age of initiation of 18.7 years. Binge drinking was reported by 51% of drinkers, 43% of whom reported binge drinking 4 or more times. Drinking and driving was reported by nearly one quarter of those who drive a car/motorcycle. Current drinking was more likely among males, ages 25-34, single, urban, and those with more education. Binge drinking was more likely among males, older age groups, and people who started drinking before 18. Drinking and driving was higher among males, those with more education, and rural residents. Those who binge-drink were nearly 70% more likely to report DD. All behaviors varied significantly among Brazilian states. Given their potential health consequences, the levels of injurious alcohol behaviors observed here warrant increased attention from Brazilian policymakers and civil society.

  4. Socioeconomic Status and Age Variations in Health-Related Quality of Life: Results From the National Health Measurement Study

    Science.gov (United States)

    Cherepanov, Dasha; Palta, Mari; Dunham, Nancy Cross; Feeny, David; Fryback, Dennis G.

    2009-01-01

    Objectives We examine whether multiple health-related quality of life (HRQoL) measures are stratified by socioeconomic status (SES) and age in the United States. Methods Data are from the 2005/2006 National Health Measurement Study, a telephone survey of a nationally representative sample of U.S. adults. We plot mean HRQoL scores by SES within age groups. Regression analyses test whether education, income, and assets each have independent associations with three “preference-based” HRQoL measures and self-rated health (SRH). We test whether these associations vary by age. Results There are SES disparities in HRQoL and SRH among adults in the United States at all age groups. Income differentials in HRQoL are strong across current adult age cohorts, except the 75–89 age cohort. Education and assets have statistically significant but weaker associations with HRQoL. All three SES measures are associated with SRH (net of each other) at every age group. Those in the lowest income and education groups in the 35–44 age cohort have worse HRQoL and SRH than those in higher SES groups in the 65+ age cohort. Discussion Significant improvements in HRQoL at the population level will only be possible if we improve the HRQoL of people at the lowest end of the socioeconomic distribution. PMID:19307286

  5. Psychiatric correlates of past year adult bullying behaviors: Findings from the National Epidemiology Survey of Alcohol and Related Conditions.

    Science.gov (United States)

    McMillan, Katherine A; Thorisdottir, Audur S; Asmundson, Gordon J G

    2016-12-30

    Previous research on bully perpetration and psychiatric outcomes has been limited to examination of lifetime associations and has not included evaluation of posttraumatic stress disorder (PTSD), despite previously reported correlations between PTSD and anger and aggression. The purpose of the present study was to provide a comprehensive evaluation of the association between bullying behaviour and mental disorders within a past-year framework. Data was obtained from Wave 2 of the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC; n=34,653), a nationally-representative survey of American adults. Cross-tabulations and logistic regression analyses were conducted to evaluate the relationship between bullying behaviour and psychiatric diagnosis. A total of 239 individuals (138 males, 101 females) reported engaging in bullying behaviour within the past-year. Mood, anxiety, substance use, and personality disorders were all more common among bully perpetrators compared to others. Of note, strong associations were found between PTSD and bully perpetration. Findings from the current study demonstrate strong associations between bullying perpetration and mental health concerns. The proximity of bullying behaviors and mental health concerns may be important, suggesting avenues for efforts at intervention and bullying prevention. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  6. Modeling and control of a hydraulically actuated flexible-prismatic link robot

    International Nuclear Information System (INIS)

    Love, L.; Kress, R.; Jansen, J.

    1996-12-01

    Most of the research related to flexible link manipulators to date has focused on single link, fixed length, single plane of vibration test beds. In addition, actuation has been predominantly based upon electromagnetic motors. Ironically, these elements are rarely found in the existing industrial long reach systems. This manuscript describes a new hydraulically actuated, long reach manipulator with a flexible prismatic link at Oak Ridge National Laboratory (ORNL). Focus is directed towards both modeling and control of hydraulic actuators as well as flexible links that have variable natural frequencies

  7. An Empirical Study on Ways of Coping with Job-related Stress among National College and University Librarian in Taiwan

    Directory of Open Access Journals (Sweden)

    Chen Su-may Sheih

    2004-03-01

    Full Text Available Stress is not a naturedly bad thing - it may be stimulating, motivating and provide excitement to individuals. However, when it exceeds individuals’ ability to cope it becomes harmful both to library and staff. Adequate coping strategies keep the librarians in a state of good health and high job performance. The purpose of this study is trying to explore librarians’ ways of coping with job-related stress in the library settings of national colleges and universities in Taiwan. The study indicates that librarians’ ways of coping are both problem-focused and emotion-focused. And as the stress getting greater, librarians are inclined to cope with emotion-focused ways.[Article content in Chinese

  8. Fundamentals of establishment of the European model of implementation of copyright and related rights of national scientific and educational staff

    Directory of Open Access Journals (Sweden)

    Polyova Tetiana

    2016-04-01

    Full Text Available National higher education system has considerable scientific and educational potential. In higher education the educational process and scientific research are interrelated, and the scientific and teaching staff are the main participants of intellectual creative activity, that creates scientific works. Declaratively the state creates conditions for motivation (encouragement of scientists’ creativity, but universities generally do not pay compensation to the authors (performers for using the results of their intellectual activity, which indicates the absence of civilized mechanism of implementing the rights in this area. It is also an indicator of the absence of effective methods of copyright protection by the state. The study does not cover all the aspects of the target problem, because the prospect of the further study is seen in the matters, related to the emergence and implementation of copyright in higher education.

  9. Maturity status influences the relative age effect in national top level youth alpine ski racing and soccer

    Science.gov (United States)

    Müller, Lisa; Gonaus, Christoph; Perner, Christoph; Müller, Erich; Raschner, Christian

    2017-01-01

    Since the relative age effect (RAE) characterizes a problem in all age categories of alpine ski racing and soccer and the fact that, yet, to date the underlying factors have not been well investigated, the aim of the present study was to assess the influence of the biological maturity status on the RAE among youth alpine ski racers (YSR) and soccer players (SP). In total, 183 male and female YSR selected for national final races and 423 male SP selected for Elite Youth Development Centres were investigated. Additionally, a comparison group of 413 non-athletes was evaluated. The birth months were split into four relative age quarters. The biological maturity status was assessed by the age at peak height velocity (APHV) method; according to the M±SD of the comparison group, the athletes were divided into normal, early and late maturing. Chi2-tests indicated a significant RAE among YSR (χ2(3,N = 183) = 18.0; psports are effectively based on early biological development and relatively older age, both of which should be considered in future in the talent selection process. In this context, the easy feasible method of assessing the APHV can be used. PMID:28759890

  10. Culture as an explanation for substance-related problems: a cross-national study among French and Dutch adolescents.

    Science.gov (United States)

    Knibbe, Ronald Arnold; Joosten, Jan; Choquet, Marie; Derickx, Mieke; Morin, Delphine; Monshouwer, Karin

    2007-02-01

    Our main goal was to establish whether French and Dutch adolescents differ in rates of substance-related adverse events (e.g. fights, robbery), problems with peers or socializing agents even when controlling for pattern of substance use. For problems with peers and socializing agents due to alcohol we hypothesized that, because of stronger informal control of drinking in France, French adolescents are more likely to report problems with peers and socializing agents. For adverse events due to alcohol no difference was expected after controlling for consumption patterns. For drug-related problems, the hypothesis was that, due to the more restrictive drug policy in France, French adolescents are more likely to report problems with peers, socializing agents and adverse events. Comparable surveys based on samples of adolescent schoolchildren in France (n=9646) and the Netherlands (n=4291) were used. Data were analysed using multilevel logistic regression in which school, age and gender, indicators of substance use and country were used as predictors of substance-related problems. The outcomes show that French adolescents are more likely to report problems with peers and socializing agents due to alcohol even when consumption pattern is controlled for. For adverse events due to alcohol no difference was found between French and Dutch adolescents. For drug-related problems the expected differences were found; i.e. French adolescents are more likely to report problems with peers, socializing agents and adverse events even when controlling for pattern of drug use. It is concluded that there are culturally embedded differences in the rates of some types of problems due to alcohol or drug use. With respect to alcohol use, these differences are most likely due to culturally embedded differences in the informal social control of alcohol use. The differences in rates of drug-related problems are interpreted in the context of national differences in drug policy.

  11. Young Adults' Risk Perceptions of Various Tobacco Products Relative to Cigarettes: Results From the National Young Adult Health Survey.

    Science.gov (United States)

    Wackowski, Olivia A; Delnevo, Cristine D

    2016-06-01

    Objectives Tobacco product risk perceptions may influence whether individuals use those products instead of or in addition to regular cigarettes. This study aimed to explore risk perceptions of various tobacco products relative to traditional cigarettes with young adults, a group with higher rates of tobacco use. Method We examined risk perception responses among a nationally representative sample of young adults (age 18-34 years; n = 2,871, including tobacco and non-tobacco users) from the 2011 National Young Adult Health Survey. Results Most (57.8%) respondents believed that e-cigarettes were less risky than cigarettes. Respondents were more likely to rate combustible products hookah (24.5%) and cigars (13.9%) as being less risky compared to noncombustible snus (10%) and other smokeless tobacco (SLT) products (7.1%) relative to cigarettes. Few (2.5%) rated menthol cigarettes as less risky. For e-cigarettes, hookah, and SLT, less risky beliefs were significantly higher among ever or current versus never product users. Between 22% and 33% of all respondents believed that SLT, snus, menthol cigarettes, and cigars were more risky than cigarettes, but differences in this belief between current and nonusers of these products were small and insignificant. Younger young adults were more likely to rate e-cigarettes and hookah as being "less risky" and rate cigars and SLT as being "more risky" than older young adults. Conclusion The public's views of comparative tobacco risk perceptions vary widely by tobacco product type and age-group. While "less risky" perceptions may be associated with product use, perceptions that products are "more risky" than cigarettes may not necessarily dissuade people from their use. © 2015 Society for Public Health Education.

  12. Young adults’ risk perceptions of various tobacco products relative to cigarettes – results from the National Young Adult Health Survey

    Science.gov (United States)

    Delnevo, Cristine D.

    2015-01-01

    Objectives Tobacco product risk perceptions may influence whether individuals use those products instead of or in addition to regular cigarettes. This study aimed to explore risk perceptions of various tobacco products relative to traditional cigarettes with young adults, a group with higher rates of tobacco use. Methods We examined risk perception responses among a nationally representative sample of young adults (ages 18–34)(n=2871)(including tobacco and non-tobacco users) from the 2011 National Young Adult Health Survey. Results Most (57.8%) respondents believed that e-cigarettes were less risky than cigarettes. Respondents were more likely to rate combustible products hookah (24.5%) and cigars (13.9%) as being less risky compared to non-combustible snus (10%) and other smokeless tobacco (SLT) products (7.1%) relative to cigarettes. Few (2.5%) rated menthol cigarettes as less risky. For e-cigarettes, hookah, and SLT, less risky beliefs were significantly higher among ever or current versus never product users. Between 22–33% of all respondents believed that SLT, snus, menthol cigarettes and cigars were more risky than cigarettes, but differences in this belief between current and non-users of these products were small and insignificant. Younger young adults were more likely to rate e-cigarettes and hookah as being “less risky” and rate cigars and SLT as being “more risky” than older young adults. Conclusion The public’s views of comparative tobacco risk perceptions vary widely by tobacco product type, and age group. While “less risky” perceptions may be associated with product use, perceptions that products are “more risky” than cigarettes may not necessarily dissuade people from their use. PMID:26304709

  13. Swedish National Registry of Urinary Bladder Cancer: No difference in relative survival over time despite more aggressive treatment.

    Science.gov (United States)

    Jahnson, Staffan; Hosseini Aliabad, Abolfazl; Holmäng, Sten; Jancke, Georg; Liedberg, Fredrik; Ljungberg, Börje; Malmström, Per-Uno; Rosell, Johan

    2016-01-01

    The aim of this study was to use the Swedish National Registry of Urinary Bladder Cancer (SNRUBC) to investigate changes in patient and tumour characteristics, management and survival in bladder cancer cases over a period of 15 years. All patients with newly detected bladder cancer reported to the SNRUBC during 1997-2011 were included in the study. The cohort was divided into three groups, each representing 5 years of the 15 year study period. The study included 31,266 patients (74% men, 26% women) with a mean age of 72 years. Mean age was 71.7 years in the first subperiod (1997-2001) and 72.5 years in the last subperiod (2007-2011). Clinical T categorization changed from the first to the last subperiod: Ta from 45% to 48%, T1 from 21.6% to 22.4%, and T2-T4 from 27% to 25%. Also from the first to the last subperiod, intravesical treatment after transurethral resection for T1G2 and T1G3 tumours increased from 15% to 40% and from 30% to 50%, respectively, and cystectomy for T2-T4 tumours increased from 30% to 40%. No differences between the analysed subperiods were found regarding relative survival in patients with T1 or T2-T4 tumours, or in the whole cohort. This investigation based on a national bladder cancer registry showed that the age of the patients at diagnosis increased, and the proportion of muscle-invasive tumours decreased. The treatment of all tumour stages became more aggressive but relative survival showed no statistically significant change over time.

  14. Lessons from the Central European History – Wars and Changes of Ethnic and National Relations in Central Europe during the 20th Century

    Czech Academy of Sciences Publication Activity Database

    Prokš, Petr

    2015-01-01

    Roč. 16, č. 60 (2015), s. 91-106 ISSN 1586-4197 Institutional support: RVO:67985963 Keywords : World War I * World War II * Central Europe * Czechoslovakia * National Relations Subject RIV: AB - History

  15. Linking unlinkability

    NARCIS (Netherlands)

    Brusó, Mayla; Chatzikokolakis, Konstantinos; Etalle, Sandro; den Hartog, Jeremy

    Unlinkability is a privacy property of crucial importance for several systems (such as RFID or voting systems). Informally, unlinkability states that, given two events/items in a system, an attacker is not able to infer whether they are related to each other. However, in the literature we find

  16. Related factors and incidence risk of acute myocardial infarction among the people with disability: A national population-based study.

    Science.gov (United States)

    Huang, Ying-Ying; Kung, Pei-Tseng; Chiu, Li-Ting; Tsai, Wen-Chen

    2014-11-06

    Cardiovascular disease has always been a leading cause of death worldwide. Because the mobility of people with disability is relatively decreased, their risk of cardiovascular disease is increased. This study investigated the risks and relevant factors of acute myocardial infarction (AMI) among people with disability. This is a retrospective cohort study based on secondary data analysis. This study focused on 798,328 people with disability who were aged 35 and above during 2002-2008 and were registered in the National Disability Registration Database; the relevant medical data from 2000 to 2011 were acquired from the National Health Insurance Research Database. A Cox proportional hazards model was adopted for analyzing the relative AMI risks among different disability types and finding latent risk factors. The results indicated that the AMI incidence rate (per 1000 patient-years) among people with disability was 2.48. Men had an AMI incidence rate of 2.68 per 1000 patient-years, which was significantly higher than that of women (2.21; pdisability aged 65 and above had an AMI risk that was 5.01-6.03 times the risk for people with disability aged below 45. Disabled indigenous people had a relatively higher AMI risk (HR=1.35, 95% CI=1.19-1.52). The AMI risk for people with disability with a Charlson comorbidity index (CCI) of 4 and above was 5.89 times (95% CI=5.56-6.25) the risk for those with a CCI of 0. Compared with people with physical disabilities, people with visual impairment and people with dysfunctional primary organs had significantly higher AMI risks (HR=1.15; HR=1.66). This study found that people with disability who were male, aged 65 and above, married, indigenous, with physical disabilities, with high comorbidity, or with high disability levels had relatively higher AMI risks than other people with disability. The research outcomes can be used as references by public health authorities to improve the engagement of people with disability in AMI

  17. Physical Samples Linked Data in Action

    Science.gov (United States)

    Ji, P.; Arko, R. A.; Lehnert, K.; Bristol, S.

    2017-12-01

    Most data and metadata related to physical samples currently reside in isolated relational databases driven by diverse data models. How to approach the challenge for sharing, interchanging and integrating data from these difference relational databases motivated us to publish Linked Open Data for collections of physical samples, using Semantic Web technologies including the Resource Description Framework (RDF), RDF Query Language (SPARQL), and Web Ontology Language (OWL). In last few years, we have released four knowledge graphs concentrated on physical samples, including System for Earth Sample Registration (SESAR), USGS National Geochemical Database (NGDC), Ocean Biogeographic Information System (OBIS), and Earthchem Database. Currently the four knowledge graphs contain over 12 million facets (triples) about objects of interest to the geoscience domain. Choosing appropriate domain ontologies for representing context of data is the core of the whole work. Geolink ontology developed by Earthcube Geolink project was used as top level to represent common concepts like person, organization, cruise, etc. Physical sample ontology developed by Interdisciplinary Earth Data Alliance (IEDA) and Darwin Core vocabulary were used as second level to describe details about geological samples and biological diversity. We also focused on finding and building best tool chains to support the whole life cycle of publishing linked data we have, including information retrieval, linked data browsing and data visualization. Currently, Morph, Virtuoso Server, LodView, LodLive, and YASGUI were employed for converting, storing, representing, and querying data in a knowledge base (RDF triplestore). Persistent digital identifier is another main point we concentrated on. Open Researcher & Contributor IDs (ORCIDs), International Geo Sample Numbers (IGSNs), Global Research Identifier Database (GRID) and other persistent identifiers were used to link different resources from various graphs with

  18. Bullying perpetration and victimization as externalizing and internalizing pathways: A retrospective study linking parenting styles and self-esteem to depression, alcohol use, and alcohol-related problems

    OpenAIRE

    Luk, Jeremy W; Patock-Peckham, Julie A; Medina, Mia; Terrell, Nathan; Belton, Daniel; King, Kevin M

    2016-01-01

    Emerging research suggests significant positive associations between bullying and substance use behaviors. However, these studies typically focused either on the link between substance use and bullying perpetration or victimization, and few have conceptualized bullying perpetration and/or victimization as mediators. In this study, we simultaneously tested past bullying perpetration and victimization as mediational pathways from retrospective report of parenting styles and global self-esteem t...

  19. The A-chain of insulin contacts the insert domain of the insulin receptor. Photo-cross-linking and mutagenesis of a diabetes-related crevice.

    Science.gov (United States)

    Huang, Kun; Chan, Shu Jin; Hua, Qing-xin; Chu, Ying-Chi; Wang, Run-ying; Klaproth, Birgit; Jia, Wenhua; Whittaker, Jonathan; De Meyts, Pierre; Nakagawa, Satoe H; Steiner, Donald F; Katsoyannis, Panayotis G; Weiss, Michael A

    2007-11-30

    The contribution of the insulin A-chain to receptor binding is investigated by photo-cross-linking and nonstandard mutagenesis. Studies focus on the role of Val(A3), which projects within a crevice between the A- and B-chains. Engineered receptor alpha-subunits containing specific protease sites ("midi-receptors") are employed to map the site of photo-cross-linking by an analog containing a photoactivable A3 side chain (para-azido-Phe (Pap)). The probe cross-links to a C-terminal peptide (residues 703-719 of the receptor A isoform, KTFEDYLHNVVFVPRPS) containing side chains critical for hormone binding (underlined); the corresponding segment of the holoreceptor was shown previously to cross-link to a Pap(B25)-insulin analog. Because Pap is larger than Val and so may protrude beyond the A3-associated crevice, we investigated analogs containing A3 substitutions comparable in size to Val as follows: Thr, allo-Thr, and alpha-aminobutyric acid (Aba). Substitutions were introduced within an engineered monomer. Whereas previous studies of smaller substitutions (Gly(A3) and Ser(A3)) encountered nonlocal conformational perturbations, NMR structures of the present analogs are similar to wild-type insulin; the variant side chains are accommodated within a native-like crevice with minimal distortion. Receptor binding activities of Aba(A3) and allo-Thr(A3) analogs are reduced at least 10-fold; the activity of Thr(A3)-DKP-insulin is reduced 5-fold. The hormone-receptor interface is presumably destabilized either by a packing defect (Aba(A3)) or by altered polarity (allo-Thr(A3) and Thr(A3)). Our results provide evidence that Val(A3), a site of mutation causing diabetes mellitus, contacts the insert domain-derived tail of the alpha-subunit in a hormone-receptor complex.

  20. The Advisory Opinion of the International Tribunal for the Law of the Sea: Matters related to the determination of effective link between the States and the legal persons they sponsor to carry out activities in the Area

    Directory of Open Access Journals (Sweden)

    Juan Nicolás Guerrero Peniche

    2012-12-01

    Tribunal for the Law of the Sea so it could be clarified. The advisory opinion of the Tribunal advanced conclusions particularly relevant for the determination of a nationality link between the legal persons and the States that sponsor them. This matter, which plays an essential role for achieving an effective protection of the marine environment within the sponsorship mechanisms for exploration and exploitation of the resources of the Area, also has some relevant consequences for the activities in reserved areas.