WorldWideScience

Sample records for regulatory research res

  1. Progress in research and regulatory development by the Materials Engineering Branch, RES Engineering Division

    International Nuclear Information System (INIS)

    Serpan, C.Z. Jr.

    1988-01-01

    Much activity has been underway In NRC this past year on definition of aging Issues for nuclear power plants that will be applicable to the regulatory considerations of applications for license renewals following the Initial 40-year operating period. The Materials Engineering Branch has been reviewing its program to assure that aging Issues are prominent, and to identify regulatory documents that will have to be validated or revised to provide a proper basis for license renewal safety evaluation. A report on the branch plan for aging and needs for extended life review is under preparation and should be available early in 1988

  2. Regulatory design for RES-E support mechanisms: Learning curves, market structure, and burden-sharing

    International Nuclear Information System (INIS)

    Batlle, C.; Pérez-Arriaga, I.J.; Zambrano-Barragán, P.

    2012-01-01

    Drawing from relevant experiences in power systems around the world, this paper offers a review of existing policy support mechanisms for RES-E, with a detailed analysis of their regulatory implications. While recent studies provide an account of current RES-E support systems, in this paper we focus on some of the impacts these mechanisms have on the overall energy market structure and its performance. Given the rising importance of RES-E in systems everywhere, these impacts should no longer be overlooked. - Highlights: ► This paper offers a critical review of RES-E support mechanisms and their regulatory implications. ► The discussion focuses on how the different schemes impact the performance of the energy markets. ► We propose to redesign of current RES-E mechanisms to optimize incentives and market performance. ► Our recommendation is also to gradually move from price-based mechanisms to auctions.

  3. Research and regulatory review

    International Nuclear Information System (INIS)

    Macleod, J.S.; Fryer, D.R.H.

    1979-01-01

    To enable the regulatory review to be effectively undertaken by the regulatory body, there is a need for it to have ready access to information generated by research activities. Certain advantages have been seen to be gained by the regulatory body itself directly allocating and controlling some portion of these activities. The princial reasons for reaching this conclusion are summarised and a brief description of the Inspectorates directly sponsored programme outlined. (author)

  4. ResDE Two-Component Regulatory System Mediates Oxygen Limitation-Induced Biofilm Formation by Bacillus amyloliquefaciens SQR9.

    Science.gov (United States)

    Zhou, Xuan; Zhang, Nan; Xia, Liming; Li, Qing; Shao, Jiahui; Shen, Qirong; Zhang, Ruifu

    2018-04-15

    Efficient biofilm formation and root colonization capabilities facilitate the ability of beneficial plant rhizobacteria to promote plant growth and antagonize soilborne pathogens. Biofilm formation by plant-beneficial Bacillus strains is triggered by environmental cues, including oxygen deficiency, but the pathways that sense these environmental signals and regulate biofilm formation have not been thoroughly elucidated. In this study, we showed that the ResDE two-component regulatory system in the plant growth-promoting rhizobacterium Bacillus amyloliquefaciens strain SQR9 senses the oxygen deficiency signal and regulates biofilm formation. ResE is activated by sensing the oxygen limitation-induced reduction of the NAD + /NADH pool through its PAS domain, stimulating its kinase activity, and resulting in the transfer of a phosphoryl group to ResD. The phosphorylated ResD directly binds to the promoter regions of the qoxABCD and ctaCDEF operons to improve the biosynthesis of terminal oxidases, which can interact with KinB to activate biofilm formation. These results not only revealed the novel regulatory function of the ResDE two-component system but also contributed to the understanding of the complicated regulatory network governing Bacillus biofilm formation. This research may help to enhance the root colonization and the plant-beneficial efficiency of SQR9 and other Bacillus rhizobacteria used in agriculture. IMPORTANCE Bacillus spp. are widely used as bioinoculants for plant growth promotion and disease suppression. The exertion of their plant-beneficial functions is largely dependent on their root colonization, which is closely related to their biofilm formation capabilities. On the other hand, Bacillus is the model bacterium for biofilm study, and the process and molecular network of biofilm formation are well characterized (B. Mielich-Süss and D. Lopez, Environ Microbiol 17:555-565, 2015, https://doi.org/10.1111/1462-2920.12527; L. S. Cairns, L. Hobley, and

  5. 77 FR 9273 - WORKSHOP Sponsored by the Nuclear Regulatory Commission and the Electric Power Research Institute...

    Science.gov (United States)

    2012-02-16

    ... Commission and the Electric Power Research Institute on the Treatment of Probabilistic Risk Assessment.... SUMMARY: The U.S. Nuclear Regulatory Commission (NRC), Office of Nuclear Regulatory Research (RES), in cooperation with the Electric Power Research Institute (EPRI), will hold a joint workshop on the Treatment of...

  6. Human Factors Regulatory Research Program Plan, FY 1989--FY 1992

    International Nuclear Information System (INIS)

    Coffman, F.; Persensky, J.; Ryan, T.; Ramey-Smith, A.; Goodman, C.; Serig, D.; Trager, E; Nuclear Regulatory Commission, Washington, DC; Nuclear Regulatory Commission, Washington, DC; Nuclear Regulatory Commission, Washington, DC

    1989-10-01

    This report describes the currently ongoing (FY 1989) and planned (FY 1989-1992) Human Factors Regulatory Research Program in the NRC Office of Nuclear Regulatory Research (RES). Examples of the influence of human factors on nuclear safety are presented, and the role of personnel is discussed. Current regulatory issues associated with human factors in the nuclear system and the purpose of the research plan are provided. The report describes the research process applied to the human factors research issues and the program activities: Personnel Performance Measurement, Personnel Subsystem, Human-System Interface. Organization and Management, and Reliability Assessment. The research being conducted within each activity is summarized along with the objectives, background information, and expected regulatory products. Budget and personnel forecasts are provided along with a summary of contractors performing some of the ongoing research. Appendices contain a chronology of human factors research at NRC, a description of the research approach, an update on human factors programs and initiatives in RES and other NRC offices, and the integration among these programs. 46 refs., 5 tabs

  7. Principles of good regulatory research

    International Nuclear Information System (INIS)

    Rogers, K.

    1991-01-01

    The Commissioner of the US Regulatory Commission addresses several important research-related subjects. The paper describes the Agency philosophy with respect to independence, openness, efficiency, clarity, and reliability; research philosophy with respect to the need for research, the need for quality, and the need for efficiency; research areas with respect to plant aging, human factors, severe accident analysis, advanced reactors, and radioactive waste management; and systems approach to reactor operations, training, licensing, and maintenance

  8. Current experience with support schemes for RES-E in Europe. A regulatory point of view

    International Nuclear Information System (INIS)

    Lackner, Ursula

    2006-01-01

    The need to reduce the dependence of the European economy on imported primary energy and the impact of fossil fuels on the environment has encouraged countries to increase the share of renewable energy sources (RES) for electricity supply. EU Directive 2001/77/EC requires EU Member States to take appropriate steps to introduce new incentive mechanisms in order to reach the target of generating 21 % of the electricity in the EU from RES. At the same time EU Directive 2003/54/EC takes significant steps towards establishing a single market in electricity across the EU. Under this directive, European energy regulators have a number of responsibilities. These include the avoidance of discrimination and the promotion of effective competition along with an efficient functioning of the market. One of their main tasks is to ensure that European consumers pay a final electricity price that is as cost reflective as possible. The final price shall also reflect the social and the environmental costs. At the current stage it is not unlikely that the promotion of renewable energy sources will create significant barriers and distortions on the liberalized electricity market. Several issues arising from the implementation of renewable incentive schemes and policies can be identified and are analysed below; - Conflicting targets on EU-Level; - The variation in the level of incentives may be greater among Member States than is justified by the real level of technology costs, or other factors; - Unbalanced burden sharing for final consumers, due to different allocation mechanisms and designs of support schemes; -The regulation and charges for relevant items of the electricity chain, such as connection and balancing costs, vary significantly among Member States and may introduce competitive advantages. The contents of the paper is as follows: 1 Background; 2 Conflicting targets on EU-Level; 3 Different support levels; 4 Unbalanced burden sharing of final customers; 5 Allocation of

  9. Research program on regulatory safety research

    International Nuclear Information System (INIS)

    Mailaender, R.

    2010-02-01

    This paper elaborated for the Swiss Federal Office of Energy (SFOE) presents the synthesis report for 2009 made by the SFOE's program leader on the research program concerning regulatory nuclear safety research, as co-ordinated by the Swiss Nuclear Safety Inspectorate ENSI. Work carried out in various areas is reviewed, including that done on reactor safety, radiation protection and waste disposal as well as human aspects, organisation and safety culture. Work done concerning materials, pressure vessel integrity, transient analysis, the analysis of serious accidents in light-water reactors, fuel and material behaviour, melt cooling and concrete interaction is presented. OECD data bank topics are discussed. Transport and waste disposal research at the Mont Terri rock laboratory is looked at. Requirements placed on the personnel employed in nuclear power stations are examined and national and international co-operation is reviewed

  10. Safety research programs sponsored by Office of Nuclear Regulatory Research

    International Nuclear Information System (INIS)

    Weiss, A.J.; Azarm, A.; Baum, J.W.

    1989-07-01

    This progress report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the Division of Regulatory Applications, Division of Engineering, Division of Safety Issue Resolution, and Division of Systems Research of the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research following the reorganization in July 1988. The previous reports have covered the period October 1, 1976 through September 30, 1988

  11. Research in the regulatory context

    International Nuclear Information System (INIS)

    Frescura, G.

    2001-01-01

    The purpose of this paper is to summarize the actions taken by the OECD/NEA to help its member countries deal with the problem of maintaining adequate safety research programmes to ensure effective regulation and operation of nuclear power plants. In particular the paper will summarize the conclusions of a major workshop held in June 2001 in which top regulators, heads of industry and research organisations discussed in broad terms what is needed to ensure adequate research capability. A number of collective needs have been identified, some of the key recommendations are: -) thermo-hydraulics: maintain one major facility per reactor type because of the need to perform tests, to support code development and provide educational opportunities; -) severe accident: address the need for a centre of excellence in fuel-coolant interaction and fission product behaviour; -) fuel reactor physics and integrity of structures: maintain status of hot cells and research reactors; -) human factors and plant control and monitoring: maintain the Halden project as a centre of excellence; -) seismic: monitor availability of large shaking tables; and -) fire safety: establish international database, consider possible additional research

  12. Research in the regulatory context

    Energy Technology Data Exchange (ETDEWEB)

    Frescura, G. [OECD Nuclear Energy Agency, 92 - Issy les Moulineaux (France)

    2001-07-01

    The purpose of this paper is to summarize the actions taken by the OECD/NEA to help its member countries deal with the problem of maintaining adequate safety research programmes to ensure effective regulation and operation of nuclear power plants. In particular the paper will summarize the conclusions of a major workshop held in June 2001 in which top regulators, heads of industry and research organisations discussed in broad terms what is needed to ensure adequate research capability. A number of collective needs have been identified, some of the key recommendations are: -) thermo-hydraulics: maintain one major facility per reactor type because of the need to perform tests, to support code development and provide educational opportunities; -) severe accident: address the need for a centre of excellence in fuel-coolant interaction and fission product behaviour; -) fuel reactor physics and integrity of structures: maintain status of hot cells and research reactors; -) human factors and plant control and monitoring: maintain the Halden project as a centre of excellence; -) seismic: monitor availability of large shaking tables; and -) fire safety: establish international database, consider possible additional research.

  13. Needs of research for regulatory purposes

    International Nuclear Information System (INIS)

    Wanner, H.

    2010-01-01

    Hans Wanner, Swiss Federal Nuclear Safety Inspectorate (ENSI), presented a general overview of regulatory research at the international level based on a preliminary input from international colleagues and observed that the question of active involvement of nuclear regulatory and supervisory bodies in R and D projects has become a topic of increasing interest in recent years even if the way in which research is included in regulatory activities varies from country to country. The range spans from countries with no regulatory R and D activities to countries with extensive activities that are often carried out by independent research organisations acting on behalf of the regulatory body. In a few countries, the regulator and implementer have their research carried out by the same research institutes. As an example H. Wanner explained the organisation of R and D work in Switzerland. He presented the potential merits of R and D work carried out by the regulator and introduced a number of questions that would gain from being addressed at an international level. He stressed that the R and D work performed by the implementer must be comprehensive and there should be, in principle, no need for complementary work by the regulatory body. Nevertheless, R and D work of the regulator has still several merits. It improves the regulator's necessary competence to review the safety case allowing it to rely on the scientific community. It provides the regulator's independence, allowing a different view on the safety case from the implementer's view. By bringing to the fore the scientific and technical ability of the regulator, R and D work by the regulator provides additional confidence to the stakeholders in the credibility of the regulator. There may exist further motivations for the regulator to carry out its own R and D projects, among which is the verification of key safety issues or the investigation of topics not addressed by the implementer, i.e., to fill scientific gaps. The

  14. Dietary Supplements: Regulatory Challenges and Research Resources.

    Science.gov (United States)

    Dwyer, Johanna T; Coates, Paul M; Smith, Michael J

    2018-01-04

    Many of the scientific and regulatory challenges that exist in research on the safety, quality and efficacy of dietary supplements are common to all countries as the marketplace for them becomes increasingly global. This article summarizes some of the challenges in supplement science and provides a case study of research at the Office of Dietary Supplements at the National Institutes of Health, USA, along with some resources it has developed that are available to all scientists. It includes examples of some of the regulatory challenges faced and some resources for those who wish to learn more about them.

  15. The Union and Médecins Sans Frontières approach to operational research.

    Science.gov (United States)

    Harries, A D; Rusen, I D; Reid, T; Detjen, A K; Berger, S D; Bissell, K; Hinderaker, S G; Edginton, M; Fussell, M; Fujiwara, P I; Zachariah, R

    2011-02-01

    Operational research (OR) has become a hot topic at national meetings, international conferences and donor fora. The International Union Against Tuberculosis and Lung Disease (The Union) and Médecins Sans Frontières (MSF) Operational Centre Brussels strongly promote and implement OR with colleagues in low- and middle-income countries. Here we describe how the two organisations define OR, and explain the guiding principles and methodology that underpin the strategy for developing and expanding OR in those countries. We articulate The Union's and MSF's approach to supporting OR, highlighting the main synergies and differences. Then, using the Malawi National Tuberculosis Control Programme as an example, we show how OR can be embedded within tuberculosis control activities, leading to changes in policy and practice at the national level. We discuss the difficult, yet vitally important, issue of capacity building, and share our vision of a new paradigm of product-related training and performance-based OR fellowships as two ways of developing the necessary skills at country level to ensure research is actually performed. Finally, we highlight the need to consider and incorporate into practice the ethical components of OR. This is a key moment to be involved in OR. We are confident that in partnership with interested stakeholders, including the World Health Organization, we can stimulate the implementation of quality, relevant OR as an integral part of health service delivery that in turn will lead to better health for people, particularly for those living in the poorer parts of the world.

  16. Dietary Supplements: Regulatory Challenges and Research Resources

    OpenAIRE

    Johanna T. Dwyer; Paul M. Coates; Michael J. Smith

    2018-01-01

    Many of the scientific and regulatory challenges that exist in research on the safety, quality and efficacy of dietary supplements are common to all countries as the marketplace for them becomes increasingly global. This article summarizes some of the challenges in supplement science and provides a case study of research at the Office of Dietary Supplements at the National Institutes of Health, USA, along with some resources it has developed that are available to all scientists. It includes e...

  17. Regulatory research program for 1987/88

    International Nuclear Information System (INIS)

    1987-01-01

    The regulatory research program of Canada's Atomic Energy Control Board (AECB) is intended to augment the AECB's research program beyond the capability of in-house resources. The overall objective of the research program is to produce pertinent and independent information that will assist the Board and its staff in making correct, timely and credible decisions on regulating nuclear energy. The program covers the following areas: the safety of nuclear facilities, radioactive waste management, health physics, physical security, and the development of regulatory processes. Sixty-seven projects are planned for 1987/88; as well, there are some projects held in reserve in case funding becomes available. This information bulletin contains a list of the projects with a brief description of each

  18. Regulatory research / Pesquisa regulatória

    Directory of Open Access Journals (Sweden)

    Altair Souza de Assis

    2013-05-01

    Full Text Available We present in this paper the concept, importance, and scope of research into the regulatory framework of regulation and legislation, with a particular focus on legislation related to legal metrology. This study also describes a comparative analysis of the various forms of regulation and the associated regulatory research, with the ultimate goal of better defi ning the concept and to validate the need to have research groups within a country’s regulatory bodies. Based on this work, we conclude that regulatory research is a key factor in the success of any regulatory body’s activities. Such research helps to avoid the creation of absurd or impractical regulatory barriers to a country’s technological development, or worse, to permit “orphans,” that is, technologies that are outside regulatory control, as is currently the case. Indeed, for a country to have a robust technological infrastructure, especially if it is still a developing country, strong and competent regulatory control is essential. However, this must be balanced by an atmosphere that fosters continuous and consistent technological innovation, and such development must also be self-sustainable from economic, social, and environmental viewpoints. ------------------------------------------------ Apresenta-se neste trabalho o conceito, a importância e a abrangência da pesquisa regulatória no âmbito da regulação e da regulamentação, com foco particular na regulamentação relacionada à metrologia legal. Faz-se também uma análise comparativa entre as várias formas de regular e regulamentar, e as suas pesquisas regulatórias afi ns, tendo como meta principal situar melhor o conceito e validar a necessidade de se fazer pesquisa nos órgãos e agências regulatórias do país. Com base neste trabalho, concluímos que a pesquisa regulatória é um fator chave para o sucesso de qualquer plano de ação de regulação para os agentes regulatórios do país. Ela ajuda a

  19. Reactor aging research. United States Nuclear Regulatory Commission

    International Nuclear Information System (INIS)

    Vassilaros, M.G.

    1998-01-01

    The reactor ageing research activities in USA described, are focused on the research of reactor vessel integrity, including regulatory issues and technical aspects. Current emphasis are described for fracture analysis, embrittlement research, inspection capabilities, validation od annealing rule, revision of regulatory guide

  20. The BonaRes Centre - A virtual institute for soil research in the context of a sustainable bio-economy

    Science.gov (United States)

    Wollschläger, Ute; Helming, Katharina; Heinrich, Uwe; Bartke, Stephan; Kögel-Knabner, Ingrid; Russell, David; Eberhardt, Einar; Vogel, Hans-Jörg

    2016-04-01

    Fertile soils are central resources for the production of biomass and provision of food and energy. A growing world population and latest climate targets lead to an increasing demand for both, food and bio-energy, which require preserving and improving the long-term productivity of soils as a bio-economic resource. At the same time, other soil functions and ecosystem services need to be maintained. To render soil management sustainable, we need to establish a scientific knowledge base about complex soil system processes that allows for the development of model tools to quantitatively predict the impact of a multitude of management measures on soil functions. This, finally, will allow for the provision of site-specific options for sustainable soil management. To face this challenge, the German Federal Ministry of Education and Research recently launched the funding program "Soil as a Natural Resource for the Bio-Economy - BonaRes". In a joint effort, ten collaborative projects and the coordinating BonaRes Centre are engaged to close existing knowledge gaps for a profound and systemic understanding of soil functions and their sensitivity to soil management. This presentation provides an overview of the concept of the BonaRes Centre which is responsible for i) setting up a comprehensive data base for soil-related information, ii) the development of model tools aiming to estimate the impact of different management measures on soil functions, and iii) establishing a web-based portal providing decision support tools for a sustainable soil management. A specific focus of the presentation will be laid on the so-called "knowledge-portal" providing the infrastructure for a community effort towards a comprehensive meta-analysis on soil functions as a basis for future model developments.

  1. 21 CFR 312.86 - Focused FDA regulatory research.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Focused FDA regulatory research. 312.86 Section 312.86 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Severely-debilitating Illnesses § 312.86 Focused FDA regulatory research. At the discretion of the agency...

  2. Status of nuclear regulatory research and its future perspectives

    International Nuclear Information System (INIS)

    Lee, J. I.; Kim, W. S.; Kim, M. W.

    1999-01-01

    A comprehensive investigation of the regulatory research comprising an examination of the research system, its areas and contents, and the goals and financial resources is undertaken. As a result of this study, the future direction of regulatory research and its implementation strategies are suggested to resolve the current issues emerging from this examination. The major issues identified in the study are; (a) an insufficient investment in nuclear regulatory and safety research, (b) an interfacial discrepancy between similar research areas, and (c) a limitation of utilizing research results. To resolve these issues, several measures are proposed : (1) developing a lead project to establish a comprehensive infrastructure for enhancing research cooperation between nuclear organizations including institutes, industry, and universities, with an aim to improve cooperation between projects and to strengthen overall coordination functions among research projects, (2) introducing a certification system on research outcome to promote the proliferation of both research results themselves and their application with a view to enhancing the research quality, (3) strengthening the cooperative system to promote the international cooperative research, and (4) digitalizing all documents and materials relevant to safety and regulatory research to establish KIMS (knowledge and information based management system). It is expected that the aforementioned measures suggested in this study will enhance the efficiency and effectiveness of both nuclear regulatory and safety research, if they are implemented after deliberating with the government and related nuclear industries in the near future

  3. Safety Committees for Argentinean Research Reactor - Regulatory Issues

    International Nuclear Information System (INIS)

    Perrin, Carlos D.

    2009-01-01

    In the field of radiological and nuclear safety, the Nuclear Regulatory Authority (ARN) of Argentina controls three research reactors and three critical assemblies, by means of evaluations, audits and inspections, in order to ensure the fulfillment of the requirements established in the Licenses, in the Regulatory Standards and in the Mandatory Documentation in general. From the Nuclear Regulatory Authority's point of view, within the general process of research reactors safety management, the Operational Organization self verification of radiological and nuclear safety plays an outstanding role. In this aspect the ARN has established specific requirements in the Regulatory Standards, in the Operation Licenses and in the Operational Limits and Conditions. These requirements include the figure of different safety committees, which act as reviewers or advisers in diverse situations. This paper describes the main characteristics of the committees, their function, scope and the regulatory documents where the requirements are included. (author)

  4. U.S. Nuclear Regulatory Commission natural analogue research program

    International Nuclear Information System (INIS)

    Kovach, L.A.; Ott, W.R.

    1995-01-01

    This article describes the natural analogue research program of the U.S. Nuclear Regulatory Commission (US NRC). It contains information on the regulatory context and organizational structure of the high-level radioactive waste research program plan. It also includes information on the conditions and processes constraining selection of natural analogues, describes initiatives of the US NRC, and describes the role of analogues in the licensing process

  5. Regulatory research for waste disposal - Objectives and international approaches

    International Nuclear Information System (INIS)

    Wanner, Hans; Fischer-Appelt, Klaus; Pescatore, Claudio

    2011-01-01

    The question of active involvement of nuclear regulatory and supervisory bodies in research and development (R and D) projects has become a topic of increasing interest in recent years. The way in which research is included in regulatory activities varies from country to country, ranging from countries with no regulatory R and D activities to countries with extensive activities which are often carried out by independent research organisations acting on behalf of the regulatory body. The present report outlines (part 1) the potential merits of R and D work carried out by the regulator, and summarizes (part 2) the results of a questionnaire that was circulated among the members of the Regulators' Forum of NEA's Radioactive Waste Management Committee in 2009. Part 3 presents the conclusions of discussions within the RWMC-RF. The detailed answers to the questionnaire are also provided

  6. An appropriate level for reactor regulatory research

    International Nuclear Information System (INIS)

    Budnitz, R.J.; Kouts, H.J.C.

    1986-01-01

    In this brief paper the appropriate role for NRC's research program is set down, based on the experience of the last decade; and the broad outlines of an appropriate research program for the next decade are discussed. The two authors bring to this topic direct personal experience: they are two of only three former directors of NRC's research program in its history (the other was the last Saul Levine). The discussion considers only reactor safety research, although NRC's research program covers several other areas as well. Safeguards, environmental and health studies, waste management, and transportation are not covered

  7. The Atomic Energy Control Board's regulatory research and support program

    International Nuclear Information System (INIS)

    1988-04-01

    The purpose of the Regulatory Research and Support Program is to augment and extend the capability of the Atomic Energy Control Board's (AECB) regulatory program beyond the capability of in-house resources. The overall objective of the program is to produce pertinent and independent scientific and other knowledge and expertise that will assist the AECB in making correct, timely and credible decisions on regulating the development, application and use of atomic energy. The objectives are achieved through contracted research, development, studies, consultant and other kinds of projects administered by the Research and Radiation Protection Branch (RRB) of the AECB

  8. In medias res

    DEFF Research Database (Denmark)

    Foote, Jonathan

    2017-01-01

    nor does he begin the Trojan War ab ovo (with the egg) but always he hurries to the action and snatches the listener in medias res (into the middle of things)      Horace, Ars Poetica 145–147 Good epic poets do not commence their tale from the beginning—ab ovo (with the egg)—as Horace states......, but rather descend in medias res (into the middle of things), a reference to the Illiad opening already many years into the Trojan War. Perhaps this sentiment of plunging into the middle of action was felt by researchers in 1976 when, upon the walls of the San Lorenzo New Sacristy in Florence, they uncovered...

  9. Overview of the Nuclear Regulatory Commission's safety research program

    International Nuclear Information System (INIS)

    Beckjord, E.S.

    1989-01-01

    Accomplishments during 1988 of the Office of Nuclear Regulatory Research and the program of safety research are highlighted, and plans, expections, and needs of the next year and beyond are discussed. Topics discussed include: ECCS Appendix K Revision; pressurized thermal shock; NUREG-1150, or the PRA method performance document; resolution of station blackout; severe accident integration plan; nuclear safety research review committee; and program management

  10. Interactions of severe accident research and regulatory positions (ISARRP)

    International Nuclear Information System (INIS)

    Sehgal, B.R.

    2001-12-01

    The work Programme of the ISARRP Project was divided into several work packages. The work was conducted in the form of presentations and discussions, held during several meetings whose character was that of workshops. Short reports were prepared by the partners assigned to each task. Work Package 1: Critical review of the SA phenomenological research. The objective of this work package was to consider the progress made world-wide in research on the resolution of the outstanding phenomenological issues posed by severe accidents. Work Package 2: Relevance of severe accident research to SAMG requirements and implementation. The objective of this work package was to relate the progress made in the resolution of the SA issues to the practical matter of what results are required or have been used for the management of severe accidents. Clearly, the SAMG is the most important avenue employed by the regulatory organizations to assure themselves of the safe (from public perspective) performance of a nuclear plant in a postulated severe accident event. Work Package 3: Relevance of severe accident research to PSA and the risk informed regulatory approach. The objectives of this work package is to relate the results obtained by the severe accident research to the requirements of a PSA and of the new trend of employing the risk informed approach in promulgating regulations. Clearly a PSA identifies vulnerabilities in the knowledge base, however, their importance is decidedly plant specific. Nevertheless the uncertainties in the phenomenology or in resolution of issues lead to uncertainties in the PSA conclusions and in the adoption of the risk informed approach. Work Package 4: Questionnaire and the evaluation of responses to the questions. The purpose of this work package is to solicit the views of the regulatory organizations towards the results of the SA research and the benefits they have derived from it in terms of regulatory actions, or in the confidence they have gained

  11. Interactions of severe accident research and regulatory positions (ISARRP)

    Energy Technology Data Exchange (ETDEWEB)

    Sehgal, B.R. (comp.) [Royal Inst. of Tech., Stockholm (Sweden). Nuclear Power Safety

    2001-12-01

    The work Programme of the ISARRP Project was divided into several work packages. The work was conducted in the form of presentations and discussions, held during several meetings whose character was that of workshops. Short reports were prepared by the partners assigned to each task. Work Package 1: Critical review of the SA phenomenological research. The objective of this work package was to consider the progress made world-wide in research on the resolution of the outstanding phenomenological issues posed by severe accidents. Work Package 2: Relevance of severe accident research to SAMG requirements and implementation. The objective of this work package was to relate the progress made in the resolution of the SA issues to the practical matter of what results are required or have been used for the management of severe accidents. Clearly, the SAMG is the most important avenue employed by the regulatory organizations to assure themselves of the safe (from public perspective) performance of a nuclear plant in a postulated severe accident event. Work Package 3: Relevance of severe accident research to PSA and the risk informed regulatory approach. The objectives of this work package is to relate the results obtained by the severe accident research to the requirements of a PSA and of the new trend of employing the risk informed approach in promulgating regulations. Clearly a PSA identifies vulnerabilities in the knowledge base, however, their importance is decidedly plant specific. Nevertheless the uncertainties in the phenomenology or in resolution of issues lead to uncertainties in the PSA conclusions and in the adoption of the risk informed approach. Work Package 4: Questionnaire and the evaluation of responses to the questions. The purpose of this work package is to solicit the views of the regulatory organizations towards the results of the SA research and the benefits they have derived from it in terms of regulatory actions, or in the confidence they have gained

  12. Status of Regulatory Research for Sodium cooled Fast Reactor

    International Nuclear Information System (INIS)

    Shin, Andong

    2012-01-01

    Strategy: • Keeping up with Design Technology: – Information exchange between designer/regulation. • Involvement of Industry, Academy and Research Institute and Taking an Experts Technical Opinion: – Internal and external expert consultation for practical and reasonable results. • Participation of International Cooperation Research: – Cooperation with experienced regulatory organizations; – Keeping up with state of the art and current status of resoling issues in the field of V&V of evaluation codes for SFR

  13. Regulatory Framework for Controlling the Research Reactor Decommissioning Project

    International Nuclear Information System (INIS)

    Melani, Ai; Chang, Soon Heung

    2009-01-01

    Decommissioning is one of important stages in construction and operation of research reactors. Currently, there are three research reactors operating in Indonesia. These reactors are operated by the National Nuclear Energy Agency (BATAN). The age of the three research reactors varies from 22 to 45 years since the reactors reached their first criticality. Regulatory control of the three reactors is conducted by the Nuclear Energy Regulatory Agency (BAPETEN). Controlling the reactors is carried out based on the Act No. 10/1997 on Nuclear Energy, Government Regulations and BAPETEN Chairman Decrees concerning the nuclear safety, security and safeguards. Nevertheless, BAPETEN still lack of the regulation, especially for controlling the decommissioning project. Therefore, in the near future BAPETEN has to prepare the regulations for decommissioning, particularly to anticipate the decommissioning of the oldest research reactors, which probably will be done in the next ten years. In this papers author give a list of regulations should be prepared by BAPETEN for the decommissioning stage of research reactor in Indonesia based on the international regulatory practice

  14. Ethical and regulatory aspects of embryonic stem cell research.

    Science.gov (United States)

    Jain, Kewal K

    2002-12-01

    Ethical and regulatory issues concerning embryonic stem (ES) cell research are reviewed here a year after the controversy became a public and political issue in the US. The background of various issues are examined and the current regulations in various countries are reviewed. In the US, the debate is linked with abortion, as well as the status of a fetus as a human being, and is politically driven. Obtaining stem cells from embryonic tissues involves destruction of the embryo, to which objections are raised. Religious beliefs are examined and no serious impediments to ES cell research could be identified. Regulations vary from one country to another and it is unlikely that there will ever be any universally uniform ethical and regulatory standards for ES cell research. Currently, the most liberal and favourable environments for ES cell research are in the UK, Singapore, Sweden, India, Israel and China. Unless the US liberalises ES cell research, it may lose its lead in ES cell research and investments in this area may drift to countries with better environments for research. Suggestions are offered in this review to improve the ethical environment for ES cell research.

  15. Nudging Healthy Lifestyles – Informing Regulatory Governance with Behavioural Research

    OpenAIRE

    Alemanno , Alberto; Amir , On; Bovens , Luc; Burgess , Adam; Lobel , Orly; Powys Whyte , Kyle; Selinger , Evan

    2012-01-01

    At a time when policy makers want to change the behaviour of citizens to tackle a broad range of social problems, such as climate change, excessive drinking, obesity and crime, a promising new policy approach has appeared that seems capable of escaping the liberal reservations typically associated with all forms of regulatory action. The approach, which stems from the increasingly ubiquitous findings of behavioural research, is generally captured under the evocative concept of ‘nudge.’ Inspir...

  16. The FDA “Deeming Rule” and Tobacco Regulatory Research

    OpenAIRE

    Backinger, Cathy L.; Meissner, Helen I.; Ashley, David L.

    2016-01-01

    In May 2016, the Food and Drug Administration extended its tobacco regulatory authorities to other products meeting the definition of a tobacco product (Deeming Rule). This authority now includes, but is not limited to, electronic nicotine delivery systems (ENDS), such as electronic cigarettes, as well as all cigars, pipes, and hookahs (waterpipes). The FDA’s Center for Tobacco Products has been able to fund research projects addressing these newly deemed tobacco products through a variety of...

  17. Regulatory research and support program for 1989/90

    International Nuclear Information System (INIS)

    1989-01-01

    The Regulatory Research and Support Program is intended to augment and extend the Atomic Energy Control Board's regulatory program beyond the capability of in-house resources. The overall objective of the research and support program is to produce pertinent and independent information that will assist the Board and its staff in making correct, timely and credible decisions on regulating nuclear energy. The program is divided into eight main areas of research covering the safety of nuclear facilities, radioactive waste management, health physics, physical security and the development of regulatory processes. A total of 83 projects are planned for 1989/90, including a number which are ongoing from the previous fiscal year. Projects that are held in reserve in case funding becomes available are also listed. Most of the projects will be carried out under contracts issued through the Department of Supply and Services. This Information Bulletin contains a list of the projects with a brief description of each, and additional supporting information

  18. Behavioral Economic Laboratory Research in Tobacco Regulatory Science.

    Science.gov (United States)

    Tidey, Jennifer W; Cassidy, Rachel N; Miller, Mollie E; Smith, Tracy T

    2016-10-01

    Research that can provide a scientific foundation for the United States Food and Drug Administration (FDA) tobacco policy decisions is needed to inform tobacco regulatory policy. One factor that affects the impact of a tobacco product on public health is its intensity of use, which is determined, in part, by its abuse liability or reinforcing efficacy. Behavioral economic tasks have considerable utility for assessing the reinforcing efficacy of current and emerging tobacco products. This paper provides a narrative review of several behavioral economic laboratory tasks and identifies important applications to tobacco regulatory science. Behavioral economic laboratory assessments, including operant self-administration, choice tasks and purchase tasks, can be used generate behavioral economic data on the effect of price and other constraints on tobacco product consumption. These tasks could provide an expedited simulation of the effects of various tobacco control policies across populations of interest to the FDA. Tobacco regulatory research questions that can be addressed with behavioral economic tasks include assessments of the impact of product characteristics on product demand, assessments of the abuse liability of novel and potential modified risk tobacco products (MRTPs), and assessments of the impact of conventional and novel products in vulnerable populations.

  19. Research program on regulatory safety research - Synthesis report 2008

    International Nuclear Information System (INIS)

    Mailaender, R

    2009-06-01

    This report for the Swiss Federal Office of Energy (SFOE) summarises the program's main points of interest, work done in the year 2008 and the results obtained. The main points of the research program, which is co-ordinated by the Swiss Federal Nuclear Safety Inspectorate ENSI, are discussed. Topics covered concern reactor safety as well as human, organisational and safety aspects. Work done in several areas concerning reactor safety and materials as well as interactions in severe accidents in light-water reactors is described. Radiation protection, the transport and disposal of radioactive wastes and safety culture are also looked at. Finally, national and international co-operation is briefly looked at and work to be done in 2009 is reviewed. The report is completed with a list of research and development projects co-ordinated by ENSI

  20. Overview of NRC's human factors regulatory research program

    International Nuclear Information System (INIS)

    Coffman, F.D. Jr.

    1989-01-01

    The human factors research program is divided into distinct and interrelated program activities: (1) Personnel Performance measurement, (2) Personnel Subsystem, (3) Human-System Interface, (4) Organization and Management, and (5) a group of Reliability Assessment activities. The purpose of the Personnel Performance Measurement activity is to improve the Agency's understanding of the factors influencing personnel performance and the effects on the safety of nuclear operations and maintenance by developing improvements to methods for collecting and managing personnel performance data. Personnel Subsystem research will broaden the understanding of such factors as staffing, qualifications, and training that influence human performance in the nuclear system and will develop the technical basis for regulatory guidance to reduce any adverse impact of these influences on nuclear safety. Research in the Human-System Interface activity will provide the technical basis for ensuring that the interface between the system and the human user supports safe operations and maintenance. Organization and Management research will result in the development of tools for evaluating organization and management issues within the nuclear industry. And finally, the Reliability Assessment group of activities includes multidisciplinary research that will integrate human and hardware considerations for evaluating reliability and risk in NRC licensing, inspection, and regulatory decisions

  1. ENRICH Forum: Ethical aNd Regulatory Issues in Cancer ResearcH

    Science.gov (United States)

    ENRICH Forum: Ethical aNd Regulatory Issues in Cancer ResearcH, designed to stimulate dialogue on ethical and regulatory issues in cancer research and promote awareness of developing policies and best practices.

  2. Safety and regulatory researches on the SMART reactor

    International Nuclear Information System (INIS)

    Seul, Kwang Won; Kim, Wee Kyong; Chang, Moo Hee

    2000-01-01

    The 330 MW thermal power of integral pressurized water reactor, named SMART (System integrated Modular Advanced ReacTor), is under development at the Korea Atomic Energy Research Institute (KAERI) for seawater desalination application and electricity generation. The plant is expected to install near the population zone. Thus, the public around the plant should be in depth protected from the possible release of radioactive materials, and also the fresh water should be prevented from radioactivity contamination. Currently, in parallel with the design development, the regulatory research is being conducted to identify and resolve the safety concerns of the nuclear desalination plant. Until now, some general items to be considered in the safety aspects have been identified for the conceptual design of SMART. They include the use of proven technology, application of strengthening defense-in-depth, event categorization and selection, effects of desalination plant, and maintainability of major components. These cooperative researches with regulatory body in the design stage are expected to provide an opportunity to early resolve the safety concerns and eventually the licensing stability of the SMART design. (author)

  3. Safety system upgrades to a research reactor: A regulatory perspective

    International Nuclear Information System (INIS)

    Lamarre, G.B.; Martin, W.G.

    2003-01-01

    The NRU (National Research Universal) reactor, located at the Chalk River Laboratories of Atomic Energy of Canada Limited (AECL), first achieved criticality November 3, 1957. AECL continues to operate NRU for research to support safety and reliability studies for CANDU reactors and as a major supplier of medical radioisotopes. Following a detailed systematic review and assessment of NRU's design and the condition of its primary systems, AECL formally notified the Canadian Nuclear Safety Commission's (CNSC) predecessor - the Atomic Energy Control Board - in 1992 of its intention to upgrade NRU's safety systems. AECL proposed seven major upgrades to provide improvements in shutdown capability, heat removal, confinement, and reactor monitoring, particularly during and after a seismic event. From a CNSC perspective, these upgrades were necessary to meet modern safety standards. From the start of the upgrades project, the CNSC provided regulatory oversight aimed at ensuring that AECL maintained a structured approach to the upgrades. The elements of the approach include, but are not limited to, the determination of project milestones and target dates; the formalization of the design process and project quality assurance requirements; the requirements for updated documentation, including safety reports, safety notes and commissioning reports; and the approval and authorization process. This paper details, from a regulatory perspective, the structured approach used in approving the design, construction, commissioning and subsequent operation of safety system upgrades for an existing and operating research reactor, including the many challenges faced when attempting to balance the requirements of the upgrades project with AECL's need to keep NRU operating to meet its important research and production objectives. (author)

  4. Caffeine addiction: Need for awareness and research and regulatory measures.

    Science.gov (United States)

    Jain, Shobhit; Srivastava, Adya Shanker; Verma, Raghunath Prasad; Maggu, Gaurav

    2017-02-04

    Caffeine consumption has been constantly growing in India especially among children and youngsters. Addictive potential of caffeine has long been reported, still there is lack of awareness about caffeine abuse in India. There is an intense need for appropriate public health regulatory measures and awareness about addictive potential & harms related to caffeine. To the best of our knowledge this is first case from India highlighting several important issues with progressive caffeine abuse resulting in dependence leading to physical, psychological, academic and social consequences; psychotic symptoms during intoxication; predisposing factors as impulsivity and novelty seeking traits in pre-morbid personality; psychosis in family; poor awareness of health hazards even among medical professionals. Widely variable caffeine containing products are available but caffeine content or its safety limit is not mentioned on caffeine products in India. Due to harmful consequences, legal availability to children, growing consumption of caffeine products, it is utmost essential to recognize caffeine as addictive substance and impose regulatory measures on sale, advertisement, maximum caffeine content, health consequences and safety limits of caffeine containing products. Further school teachers, parents and medical practitioners need to be made aware of health hazards of caffeine. Caffeine use shall always be enquired from patients presenting with psychiatric complaints. Further research and survey are required on caffeine use and related problems. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Regulatory Framework for Conducting Clinical Research in Canada.

    Science.gov (United States)

    Alas, Josmar K; Godlovitch, Glenys; Mohan, Connie M; Jelinski, Shelly A; Khan, Aneal A

    2017-09-01

    Research in human subjects is at the core of achieving improvements in health outcomes. For clinical trials, in addition to the peer review of the results before publication, it is equally important to consider whether the trial will be conducted in a manner that generates data of the highest quality and provides a measure of safety for the participating subjects. In Canada, there is no definitive legislation that governs the conduct of research involving human subjects, but a network of regulations at different levels does provide a framework for both principal investigators and sponsors. In this paper, we provide an overview of the federal, provincial and institutional legislation, guidelines and policies that will inform readers about the requirements for clinical trial research. This includes a review of the role of the Food and Drug Regulations under the Food and Drugs Act and the Tri-Council Policy Statement (TCPS2), an overview of provincial legislation across the country, and a focus on selected policies from institutional research ethics boards and public health agencies. Many researchers may find navigation through regulations frustrating, and there is a paucity of information that explains the interrelationship between the different regulatory agencies in Canada. Better understanding the process, we feel, will facilitate investigators interested in clinical trials and also enhance the long-term health of Canadians.

  6. Changing emphasis at the NRC's Office of Nuclear Regulatory Research

    International Nuclear Information System (INIS)

    Remick, F.J.

    1994-01-01

    One of the major objectives of the Office of Research is to ensure availability of sound technical information for timely decision making in support of the NRC's safety mission. The Office of Research is changing some of its emphasis to better meet the expected needs of the NRC's regulatory offices. Long-standing programs in support of operating reactors are nearing completion. These programs include plant aging and severe accident research for currently operating plants. This meeting will also address the new challenges faced by the NRC in its review of the advanced light water and non-light water reactors. As plant aging and severe accident research programs are nearing completion, the research activities are coming to focus on the emerging technologies, for example, digital instrumentation and control systems, both as replacement equipment for operating plants and as the technology of choice and necessity for the advanced reactors. Necessity, because analog equipment is becoming obsolete. Other examples include the use of new materials in operating plants, human factors considerations in the design and operation of the advanced plants, thermal-hydraulic characteristics of the advanced reactors, and new construction techniques

  7. Stem cell therapy clinical research: A regulatory conundrum for academia.

    Science.gov (United States)

    Nagpal, Anjali; Juttner, Chris; Hamilton-Bruce, Monica Anne; Rolan, Paul; Koblar, Simon A

    2017-12-01

    The encouraging pace of discovery and development in the field of regenerative medicine holds tremendous potential for bringing therapies to the clinic that may offer meaningful benefit to patients, particularly in diseases with no or suboptimal therapeutic options. Academic researchers will continue to play a critical role in developing concepts and therapies, thus determining whether regenerative medicine will be able to live up to this potential that clearly excites clinicians, researchers and patients alike. This review summarises recent developments in regulatory frameworks across different countries that aim to ensure adequate oversight of the development of regenerative medicine products, which are unique in structural and functional complexity when compared to traditional chemical drugs and fully characterised biological drugs. It discusses the implications of these developments for researchers aiming to make the challenging transition from laboratory to clinical development of these therapies and considers possible pragmatic solutions that could accelerate this process that is essential to maintain research credibility and ensure patient safety. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. January 1978 monthly highlights for Office of Nuclear Regulatory Research Programs at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Mynatt, F.R.

    1978-01-01

    Highlights of technical progress during January 1978 are presented for sixteen separate program activities which comprise the ORNL research program for the Office of Nuclear Regulatory Research's Division of Reactor Safety Research

  9. Monthly highlights for Office of Nuclear Regulatory Research Programs at Oak Ridge National Laboratory, March 1977

    International Nuclear Information System (INIS)

    Fee, G.G.

    1977-01-01

    Highlights of technical progress during March 1977 are presented for thirteen separate program activities which comprise the ORNL research program for the Office of Nuclear Regulatory Research's Division of Reactor Safety Research

  10. Safety research programs sponsored by Office of Nuclear Regulatory Research: Progress report, October 1--December 31, 1988

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, A J; Azarm, A; Baum, J W; Boccio, J L; Carew, J; Diamond, D J; Fitzpatrick, R; Ginsberg, T; Greene, G A; Guppy, J G; Haber, S B

    1989-07-01

    This progress report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the Division of Regulatory Applications, Division of Engineering, Division of Safety Issue Resolution, and Division of Systems Research of the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research following the reorganization in July 1988. The previous reports have covered the period October 1, 1976 through September 30, 1988.

  11. Safety research programs sponsored by Office of Nuclear Regulatory Research: Progress report, January 1--June 30, 1988

    Energy Technology Data Exchange (ETDEWEB)

    Baum, J W; Boccio, J L; Diamond, D; Fitzpatrick, R; Ginsberg, T; Greene, G A; Guppy, J G; Hall, R E; Higgins, J C; Weiss, A J [comp.

    1988-12-01

    This progress report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the Division of Regulatory Applications, Division of Engineering, Division of Safety Issue Resolution, and Division of Systems Research of the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research following the reorganization in July 1988. The previous reports have covered the period October 1, 1976 through December 31, 1987.

  12. Safety research programs sponsored by Office of Nuclear Regulatory Research: Progress report, January 1--June 30, 1988

    International Nuclear Information System (INIS)

    Baum, J.W.; Boccio, J.L.; Diamond, D.

    1988-12-01

    This progress report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the Division of Regulatory Applications, Division of Engineering, Division of Safety Issue Resolution, and Division of Systems Research of the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research following the reorganization in July 1988. The previous reports have covered the period October 1, 1976 through December 31, 1987

  13. Radiation safety in educational, medical and research institutions. Regulatory guide G-121

    International Nuclear Information System (INIS)

    2000-05-01

    This regulatory guide is intended to help educational, medical and research institutions design and implement radiation protection programs that meed regulatory requirements. This guide applied to educational, medical or research institutions that require a licence from the CNSC to posses or use radioactive materials. It describes programs to assure that radioactive materials are used safely during licensed activities. (author)

  14. Regulatory aspects and experience with Russian research reactors

    International Nuclear Information System (INIS)

    Morozov, S.I.

    2003-01-01

    Regulatory activity of Gosatomnadzor of Russia in the field of research reactors (RR) safety implies implementing three major aspects: 1) establishing the nuclear and radiation safety standards; 2) licensing; and 3) inspection and enforcement. Relatively recently a full set of safety standards and regulations for RR has been established thus allowing Gosatomnadzor of Russia to effectively implement its designated functions in the field of RR safety. A minimum set of these documents is shown as follows: Level I: Fundamentals: Law 'On the use of nuclear energy'; Law 'On Public radiation protection' Level II: Safety Standard: 'General Provisions for Safety of Research Facilities' Level III: Safety Rules: Nuclear Safety; - Radiation Safety; Waste Management; Safe Decommissioning of RR; Safety Analysis Report; QAP Level IV: Safety Regulations: Licensing (incl. Peer Review and Safety Assessment) - Inspection Gosatomnadzor of Russia has created and regularly updates the database on nuclear research reactors based on the actual status of all facilities. According to the database many facilities have been shutdown during recent years whether temporary or permanently waiting for the final decision on their decommissioning. For example, in 2003 Gosatomnadzor of Russia has 85 nuclear research reactors under its supervision (compared to 113 in 1998). This fact can be explained by three main reasons: 1) experimental program finished and no other programmes in place; 2) lack of resources (financial and human); 3) safety problems (physical obsolescence and ageing of equipment). One of the main difficulties in regulating RR safety is a variety of operating organizations - 21, with different financial and human resource capabilities. Ministries responsible for supporting their operation are of a little help. It becomes obvious that a unified governmental program for RR utilization is urgently needed to decide what number of RR and for what needed purposes is required to support the

  15. Role of in-house safety analysis and research activities in regulatory decision making

    International Nuclear Information System (INIS)

    Pradhan, Santosh K.; Nagrale, Dhanesh B.; Gaikwad, Avinash J.

    2015-01-01

    Achievement of an acceptable level of nuclear safety is an essential requirement for the peaceful utilization of nuclear energy. The success of Global Nuclear Safety Regime is built upon a foundation of research. Such research has been sponsored by Governments and industry and has led to improved designs, safer and more reliable plant operation, and improvements in operating plant efficiency. A key element of this research has been the nuclear safety research performed or sponsored by regulatory organizations. In part, it has been the safety research performed or sponsored by regulatory organizations that has contributed to improved safety and has laid the foundation for activities such as risk-informed regulation, plant life extension, improved plant performance (e.g. power uprates) and new plant designs. The regulatory research program is meant to improve the regulatory authority’s knowledge where uncertainty exists, where safety margins are not well-characterized, and where regulatory decisions need to be confirmed in existing or new designs and technologies. The regulatory body get research initiated either in-house or by the licensee or through technical support organizations (TSOs). Research and analysis carried out within the regulatory body is of immense value in this context. This could be in the form of analysis of safety significant events, analysis of severe accidents, review of operating experience, independent checks of critical designs and even review of operator responses under different situations towards arriving at modifications to training programmes and licensing procedures for operating personnel. A latent benefit of regulatory research carried out by the regulators themselves is that it improves their technical competence considerably which in turn leads to high quality safety reviews and improved regulation in general. The aim of the present paper is to provide an overview of role of regulatory research and the in-house regulatory safety

  16. Safety research programs sponsored by Office of Nuclear Regulatory Research: Progress report, July 1--September 30, 1988

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, A J [comp.

    1989-02-01

    This progress report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the Division of Regulatory Applications, Division of Engineering, Division of Safety Issue Resolution, and Division of Systems of the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research following the reorganization in July 1988. The previous reports have covered the period October 1, 1976 through June 30, 1988. 71 figs., 24 tabs.

  17. Safety research programs sponsored by Office of Nuclear Regulatory Research: Progress report, July 1--September 30, 1988

    International Nuclear Information System (INIS)

    Weiss, A.J.

    1989-02-01

    This progress report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the Division of Regulatory Applications, Division of Engineering, Division of Safety Issue Resolution, and Division of Systems of the US Nuclear Regulatory Commission, Office of Nuclear Regulatory Research following the reorganization in July 1988. The previous reports have covered the period October 1, 1976 through June 30, 1988. 71 figs., 24 tabs

  18. Prevention as a main objective in the regulatory practices relating to research reactors

    International Nuclear Information System (INIS)

    Waldman, Ricardo M.

    2006-01-01

    In Argentina the use of research reactors and critical facilities are very diverse, varying since the production of radionuclides, to the investigation or the teaching. Also diverse are the licensing characteristics, going from the National Atomic Energy Commission-Argentina to national universities. The strategy utilized for the regulatory control is based especially in the prevention. The prevention covers: regulatory framework, to emit standards and regulatory guides, to licensing installations and the personnel. (author) [es

  19. The regulatory requirements, design bases, researches and assessments in the field of Ukrainian NPP's seismic safety

    International Nuclear Information System (INIS)

    Mykolaychuk, O.; Mayboroda, O.; Krytskyy, V.; Karnaukhov, O.

    2001-01-01

    State Nuclear Regulatory Authority of Ukraine (SNRA) pays large attention to problem of nuclear installations seismic stability. As a result the seismic design regulatory guides is revised, additional seismic researches of NPP sites are conducted, seismic reassessment of NPP designs were begun. The experts involved address all seismic related factors under close contact with the staff of NPP, design institutes and research organizations. This document takes stock on the situation and the research programs. (author)

  20. Regulatory research program for 1986/87 project descriptions. Information bulletin 86-1

    International Nuclear Information System (INIS)

    1986-01-01

    The regulatory research program is intended to augment and extend the Atomic Energy Control Board's regulatory program beyond the capability of in-house resources. The overall objective of the research program is to produce pertinent and independent information that will assist the Board and its staff in making correct, timely and credible decisions on regulating nuclear energy. The program is divided into ten main areas of research covering the safety of nuclear facilities, radioactive waste management, health physics, physical security and the development of regulatory processes. A total of 92 projects are planned for 1986/87, including a number which are ongoing from the previous fiscal year

  1. NRC [Nuclear Regulatory Commission] safety research in support of regulation, 1987

    International Nuclear Information System (INIS)

    1988-05-01

    This report, the third in a series of annual reports, was prepared in response to congressional inquiries concerning how nuclear regulatory research is used. It summarizes the accomplishments of the Office of Nuclear Regulatory Research during 1987. The goal of this office is to ensure that research provides the technical bases for rulemaking and for related decisions in support of NRC licensing and inspection activities. This report describes both the direct contributions to scientific and technical knowledge with regard to nuclear safety and their regulatory applications

  2. Regulatory research program for 1986/87 project descriptions. Information bulletin 86-1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1986-07-08

    The regulatory research program is intended to augment and extend the Atomic Energy Control Board`s regulatory program beyond the capability of in-house resources. The overall objective of the research program is to produce pertinent and independent information that will assist the Board and its staff in making correct, timely and credible decisions on regulating nuclear energy. The program is divided into ten main areas of research covering the safety of nuclear facilities, radioactive waste management, health physics, physical security and the development of regulatory processes. A total of 92 projects are planned for 1986/87, including a number which are ongoing from the previous fiscal year.

  3. Office of Nuclear Regulatory Research summary of advanced reactors activities, June 4, 2001

    International Nuclear Information System (INIS)

    2001-01-01

    Pre-application interactions with potential licensee applicants will help NRC prepare for future submittals, through the development of the infrastructure necessary for licensing application reviews. RES has the lead for non-LWR advanced reactor pre-application initiatives and longer-range new technology initiatives. An advanced reactor group has been formed in REAHFB, and is currently performing a pre-application review of Exelon's Pebble Bed Modular Reactor. Recent industry requests for future pre application interaction include General Atomics' Gas Turbine-Modular Helium Reactor (GT-MHR) and Westinghouse International Reactor Innovative and Secure (IRIS) design. RES advanced reactors activities also include participation as an observer in DOE's Generation IV initiative. Pre-Application review objectives include the development of regulatory guidance, licensing approach, and technology-basis expectations for licensing advanced designs, including identifying significant technology, design, safety, licensing and policy issues that would need to be addressed in the licensing process. The presentation described the pre-application process for the Exelon PBMR. NRC first identifies additional information following topical meetings with Exelon, and Exelon formally documents and submits required topical Information. The staff then develops a preliminary assessment and drafts a response which is followed by stakeholder input and comments at a public workshop. Preliminary assessments are discussed with ACRS and ACNW, and Commission papers are written which provide staff positions and recommendations on proposed policy decisions. Some of the significant areas for the PBMR include: Process Issues, Legal and Financial Issues; Regulatory Framework; Fuel Performance and Qualification; Traditional Engineering Design (e.g, Nuclear, Thermal-Fluid, Materials); Fuel Cycle Safety Areas; PRA, SSC Safety Classification; PBMR Prototype Testing

  4. Regulatory research and support program for 1988/89 - project descriptions

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-03-15

    Information Bulletin, 1988. Project descriptions for the Regulatory Research and Support Program. This Information Bulletin contains a list of the projects with a brief description of each, and additional supporting information.

  5. Regulatory research and support program for 1988/89 - project descriptions

    International Nuclear Information System (INIS)

    1988-01-01

    Information Bulletin, 1988. Project descriptions for the Regulatory Research and Support Program. This Information Bulletin contains a list of the projects with a brief description of each, and additional supporting information

  6. Regulatory research and support program for 1992/93 - project descriptions. Information bulletin

    International Nuclear Information System (INIS)

    1992-01-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend the Atomic Energy Control Board's regulatory program beyond the capability of in-house resources. The overall objective of the research and support program is to produce pertinent and independent information that will assist the Board and its staff in making correct, timely and credible decisions on regulating nuclear facilities and materials

  7. Regulatory research and support program for 1992/93 - project descriptions. Information bulletin

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-03-02

    The Regulatory Research and Support Program (RSP) is intended to augment and extend the Atomic Energy Control Board`s regulatory program beyond the capability of in-house resources. The overall objective of the research and support program is to produce pertinent and independent information that will assist the Board and its staff in making correct, timely and credible decisions on regulating nuclear facilities and materials.

  8. Research ethics and integrity for social scientists beyond regulatory compliance

    CERN Document Server

    Israel, Mark

    2014-01-01

    This book explores recent developments and debates around researching ethically and with integrity, and complying with ethical requirements, and has been updated and expanded to now cover issues relating to international, indigenous, interdisciplinary and internet research.  

  9. Regulatory T Cells As Potential Targets for HIV Cure Research

    Science.gov (United States)

    Kleinman, Adam J.; Sivanandham, Ranjit; Pandrea, Ivona; Chougnet, Claire A.; Apetrei, Cristian

    2018-01-01

    T regulatory cells (Tregs) are a key component of the immune system, which maintain a delicate balance between overactive responses and immunosuppression. As such, Treg deficiencies are linked to autoimmune disorders and alter the immune control of pathogens. In HIV infection, Tregs play major roles, both beneficial and detrimental. They regulate the immune system such that inflammation and spread of virus through activated T cells is suppressed. However, suppression of immune activation also limits viral clearance and promotes reservoir formation. Tregs can be directly targeted by HIV, thereby harboring a fraction of the viral reservoir. The vital role of Tregs in the pathogenesis and control of HIV makes them a subject of interest for manipulation in the search of an HIV cure. Here, we discuss the origin and generation, homeostasis, and functions of Tregs, particularly their roles and effects in HIV infection. We also present various Treg manipulation strategies, including Treg depletion techniques and interventions that alter Treg function, which may be used in different cure strategies, to simultaneously boost HIV-specific immune responses and induce reactivation of the latent virus.

  10. EPRI/NRC-RES fire PRA guide for nuclear power facilities. Volume 1, summary and overview

    International Nuclear Information System (INIS)

    2004-01-01

    This report documents state-of-the-art methods, tools, and data for the conduct of a fire Probabilistic Risk Assessment (PRA) for a commercial nuclear power plant (NPP) application. The methods have been developed under the Fire Risk Re-quantification Study. This study was conducted as a joint activity between EPRI and the U. S. NRC Office of Nuclear Regulatory Research (RES) under the terms of an EPRI/RES Memorandum of Understanding (RS.1) and an accompanying Fire Research Addendum (RS.2). Industry participants supported demonstration analyses and provided peer review of this methodology. The documented methods are intended to support future applications of Fire PRA, including risk-informed regulatory applications. The documented method reflects state-of-the-art fire risk analysis approaches. The primary objective of the Fire Risk Study was to consolidate recent research and development activities into a single state-of-the-art fire PRA analysis methodology. Methodological issues raised in past fire risk analyses, including the Individual Plant Examination of External Events (IPEEE) fire analyses, have been addressed to the extent allowed by the current state-of-the-art and the overall project scope. Methodological debates were resolved through a consensus process between experts representing both EPRI and RES. The consensus process included a provision whereby each major party (EPRI and RES) could maintain differing technical positions if consensus could not be reached. No cases were encountered where this provision was invoked. While the primary objective of the project was to consolidate existing state-of-the-art methods, in many areas, the newly documented methods represent a significant advancement over previously documented methods. In several areas, this project has, in fact, developed new methods and approaches. Such advances typically relate to areas of past methodological debate.

  11. License renewal of the HFR research reactor - A regulatory view

    International Nuclear Information System (INIS)

    Van der Plas, Y.

    2006-01-01

    Full text: Regulatory policy in The Netherlands is having safety evaluations of a nuclear installation each ten year. Recently a periodic safety evaluation has been finished on the 45 MW High Flux Reactor (HFR) in Petten divided over the following main topics: Risk Scoping Study; HEU-LEU fuel conversion; Evaluation against a pre-defined Reference Licensing Basis; Ageing study. The Risk Scoping Study is a limited probabilistic safety assessment showing scenarios towards serious core degradation and their probabilities. Individual risks for members of the public induced by the incidents analyzed in the first phase are compared with the mortality limits and probabilistic doses limits of the national BKSE decree. For non- proliferation reasons the fuel is converted from high to low enriched uranium. Before starting the project a reference licensing basis (RLB) was defined. A list of postulated initiating events (PIEs), re-establishing a design basis has been approved. An ageing management system shall provide information on the actual status and the residual life time of the plant. The evaluation results into a list of deficiencies, recommendations and suggestions from which modifications are to be proposed. Examples are: more redundancy and separation within the reactor protection system; renewal of the emergency and decay heat cooling; addition of a secundary reactor shut down system; more redundancy in the electric power supply; addition of injection valves introducing efficient use of passive cooling inventor) under LOCA conditions; damping of the impact from loads accidentally falling into the pool. A new nuclear license was issued begin 2004, covering all modifications which are to be implemented ultimate end 2007

  12. The Swiss regulatory framework for paediatric health research.

    Science.gov (United States)

    Junod, Valerie

    2008-07-01

    Medical research on minors entails both risks and benefits. Under Swiss law, clinical trials on children, including nontherapeutic drug trials, are permissible. However, ethics committees must systematically verify that all clinical studies have a favorable risk-benefit profile. Additional safeguards are designed to ensure that children are not unnecessarily involved in research and that proper consent is always obtained. Federal Swiss law is undergoing revision to extend these protections beyond clinical trials to a broad array of health research. The Swiss drug agency also seeks to improve the incentives for pharmaceutical firms to develop new paediatric drugs and relevant paediatric drug labels.

  13. Future regulatory research needs on risk-informed and performance-based regulation

    International Nuclear Information System (INIS)

    Kim, Wong Sik; Kim, Hho Jung

    2004-01-01

    The USNRC has pursued the incorporation of risk-informed and performance-based regulation (RIPBR) into nuclear safety regulatory system, as an alternative to improve existing nuclear safety regulation of nuclear power plants, which is deterministic and prescriptive. It focuses on the use of risk insight from probabilistic safety assessment (PSA). Recently, it becomes necessary to find a way to improve regulatory efficiency and effectiveness in order to cover the increasing regulatory needs in Korea. Also, the utility has optimized design and operation of the plant using PSA insight and equipment performance information. According to the increase of the necessity for regulatory improvement using risk and performance information, KINS (Korea Institute of Nuclear Safety) is developing, as a part of a mid and long-term project of Nuclear R and D program, how to adopt the RIPBR in Korean nuclear regulatory system. As the interim results, three basic directions and several principles that are necessary to implement RIPBR model were already identified from the previous study. This paper suggests a direction to future regulatory research on RIPBR based on the previous studies including the review of international trend of RIPBR and the evaluation of risk-informed regulatory environment

  14. Nuclear regulatory guides for LWR (PWR) fuel in Japan and some related safety research

    International Nuclear Information System (INIS)

    Ichikawa, M.

    1994-01-01

    The general aspects of licensing procedure for NPPs in Japan and regulatory guides are described. The expert committee reports closely related to PWR fuel are reviewed. Some major results of reactor safety research experiments at NSPR (Nuclear Safety Research Reactor of JAERI) used for establishment of related guide, are discussed. It is pointed out that the reactor safety research in Japan supports the regularity activities by establishing and revising guides and preparing the necessary regulatory data as well as improving nuclear safety. 10 figs., 4 refs

  15. Nuclear regulatory guides for LWR (PWR) fuel in Japan and some related safety research

    Energy Technology Data Exchange (ETDEWEB)

    Ichikawa, M [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan)

    1994-12-31

    The general aspects of licensing procedure for NPPs in Japan and regulatory guides are described. The expert committee reports closely related to PWR fuel are reviewed. Some major results of reactor safety research experiments at NSPR (Nuclear Safety Research Reactor of JAERI) used for establishment of related guide, are discussed. It is pointed out that the reactor safety research in Japan supports the regularity activities by establishing and revising guides and preparing the necessary regulatory data as well as improving nuclear safety. 10 figs., 4 refs.

  16. Current products and future plan of regulatory research for risk-informed regulation in Korea

    International Nuclear Information System (INIS)

    Sung, Key Yong; Lee, Chang Ju; Kim, Woong Sik; Kim, Hho Jung

    2003-01-01

    The first phase of a regulatory research project for risk-informed regulation (RIR) and applications (RIA) was finished in March of 2002. Various results that could be useful for preparing Korean RIR system have been developed. One of the remarkable outputs is development of reactor safety goals and acceptance criteria for RIR and RIA in Korea. The Safety Goal has a 4-tier hierarchical structure and each tier has specified goals classified for their usage. Regulatory review guides for probabilistic safety assessment (PSA) including level-1, level-2 and low power and shutdown PSA have been updated by reflecting new information obtained from not only the overseas documents but also experience and insights from regulatory review in Korea. In addition, draft regulatory guides for risk-informed in-service inspection, in-service testing, importance ranking of motor-operated valves, and AOT/STI change of Technical Specifications have been developed for preparing ongoing and future licensing work. Risk-based inspection guides with inspection items selected from a viewpoint of risk importance have been suggested for Korean standard NPPs as well. In the second phase of a research project (April of 2002 to March of 2005), two regulatory research projects on RIR were initiated. One is a study on institutionalization of risk-informed and performance-based regulation. Main topics of this project are evaluation of benefit and characteristics of RIR, development of optimized Korean RIR model, impact analysis for the change of current regulation framework, and suggestion of RIR-related laws and rules. The other is focusing on the development in the areas of a regulatory audit PSA model and regulatory guides for risk monitoring, and application techniques of risk information to the significance determination of plant performance indicators and inspection findings. It is expected that a concrete scheme and detailed regulatory techniques for embodiment of RIR system in Korea will be

  17. Ethical and regulatory issues arising from proteomic research and technology.

    Science.gov (United States)

    Reymond, Marc A; Steinert, Ralf; Eder, Frank; Lippert, Hans

    2003-08-01

    Over the last two decades, medical research has begun to make extensive use of products of human origin in therapeutics, oncology, and most recently, in genetic diseases. This has raised many ethical issues involving patient rights, including issues of consent. Besides informed consent, researchers should address several topics when designing studies using human tissues. Reward for the patient should be kept minimal. Sample transfer should be organized along non-profit lines, at least in Europe. Sampling procedures should be at no risk for human volunteers, and at minimal risk for patients. Biosafety aspects should be addressed, in particular when international collaborations are intended or when collaboration is existing between academia and industry. Regulations on importation and exportation of human tissues should be observed. Data acquisition and storage should be addressed in accordance with national data protection regulations, in particular when using computerized databases. If follow-up information is to be taken, the authorization for such information should be requested. The right for patient's information (or for no information) on the research results should also be addressed. The issues of validation and patenting should be also solved, usually by informing the patient that he/she will have no commercial rights on potential research results. The patient should be told if the samples are transferred to another research laboratory or private company. Samples and related data should be destroyed on request at any time point during the course of the study. If possible, traceability of the donor should be ensured.

  18. Turning research on the psychosocial working environment into regulatory practice

    DEFF Research Database (Denmark)

    Hansen, Agnete Meldgaard; Nielsen, Klaus Tranetoft; Starheim, Liv

    The psychosocial working environment is an expanding field of research. Within the last decades a lot of knowledge has been developed in the field. The question however remains how this knowledge can be, and is being, utilized in the regulation of the psychosocial working environment. This question...... we understand this process as a translation of knowledge into policies, tools and actors dealing with the psychosocial working environment. Drawing on this understanding we develop a model that illustrates the utility of different types of research on the psychosocial working environment...

  19. Methodology for value/impact assessment of nuclear regulatory research programs

    International Nuclear Information System (INIS)

    Carlson, D.D.

    1978-12-01

    A methodology for conducting a value/impact assessment of research programs has been developed to provide the Nuclear Regulatory Commission (NRC) an improved capability for allocating resources for confirmatory research. This report presents a seven-step evaluation process and applies it to selected units of research. The methodology is intended to provide insight into the technical merits of the programs, one dimension of the complex problem of resource allocation for confirmatory research

  20. RESEARCH Analysis of time to regulatory and ethical approval of ...

    African Journals Online (AJOL)

    against TB.5-7 As a result of this work, the SATVI clinical research site in Worcester, Western ... TB vaccine in 2004 were included in this analysis. ..... Bollyky TJ, Cockburn IM, Berndt E. Bridging the gap: improving clinical development and the.

  1. TOXICOLOGICAL RESEARCH INVOLVING HUMANS: ETHICAL AND REGULATORY CONSIDERATIONS

    Science.gov (United States)

    This paper discusses the need for the Society of Toxicology (SOT) to develop a policy for ethical research in humans, and a review for publication of these studies. Observations on human beings have been the foundation upon which toxicologic knowledge has been built since the in...

  2. Res Publica aps / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2003-01-01

    Autori sõnul tekitavad tänavatel ülesseatud postrid, kus peaminister Juhan Parts kutsub üles ütlema "jah" Euroopa Liidule, kummastust, sest ehkki on tegemist Res Publica kampaaniaga, on tavainimesel raske vahet teha valitsuse justkui neutraalse referendumikampaania ja Res Publica "jah"-kampaania vahel

  3. Lõhe Res Publicas / Eve Heinla

    Index Scriptorium Estoniae

    Heinla, Eve, 1966-

    2005-01-01

    Tallinna linnapea Tõnis Palts on vastu Tallinna volikogu Res Publica fraktsiooni esimehe Toomas Tautsi abikaasa Kristina Tautsi tööleasumisele Lääne-Tallinna keskhaigla haldusjuhina. T. Paltsi kirjast Res Publica Tallinna piirkonna juhatusele. Lisa: Kuidas lahvatas pealinna võimutüli. Kommenteerivad: Maret Maripuu, Tõnis Palts, Vladimir Maslov

  4. Bridging the gap between academic research and regulatory health risk assessment of Endocrine Disrupting Chemicals.

    Science.gov (United States)

    Beronius, Anna; Hanberg, Annika; Zilliacus, Johanna; Rudén, Christina

    2014-12-01

    Regulatory risk assessment is traditionally based primarily on toxicity studies conducted according to standardized and internationally validated test guidelines. However, health risk assessment of endocrine disrupting chemicals (EDCs) is argued to rely on the efficient integration of findings from academic research. The aim of this review was to provide an overview of current developments to facilitate the use of academic research in regulatory risk assessment of chemicals and how certain aspects of study design and reporting are particularly important for the risk assessment process. By bridging the gap between academic research and regulatory health risk assessment of EDCs, scientific uncertainty in risk assessment conclusions can be reduced, allowing for better targeted policy decisions for chemical risk reduction. Copyright © 2014. Published by Elsevier Ltd.

  5. Anticipated Ethics and Regulatory Challenges in PCORnet: The National Patient-Centered Clinical Research Network.

    Science.gov (United States)

    Ali, Joseph; Califf, Robert; Sugarman, Jeremy

    2016-01-01

    PCORnet, the National Patient-Centered Clinical Research Network, seeks to establish a robust national health data network for patient-centered comparative effectiveness research. This article reports the results of a PCORnet survey designed to identify the ethics and regulatory challenges anticipated in network implementation. A 12-item online survey was developed by leadership of the PCORnet Ethics and Regulatory Task Force; responses were collected from the 29 PCORnet networks. The most pressing ethics issues identified related to informed consent, patient engagement, privacy and confidentiality, and data sharing. High priority regulatory issues included IRB coordination, privacy and confidentiality, informed consent, and data sharing. Over 150 IRBs and five different approaches to managing multisite IRB review were identified within PCORnet. Further empirical and scholarly work, as well as practical and policy guidance, is essential if important initiatives that rely on comparative effectiveness research are to move forward.

  6. A European Res publica

    Directory of Open Access Journals (Sweden)

    Ola Zetterquist

    2011-05-01

    Full Text Available The article analyses the fundamental constitutional enigma of the European Union (EU, namely whether the EU can be considered as a (from its Member States separate and independent constitutional legal order. The EU is often referred to as a legal order sui generis, i.e. of a unique character that defies traditional definitions. More specifically, the notion of an independent and separate EU is at odds with the idea of the sovereign state. The notion of the EU as a legal order sui generis is too much influenced by the models of the sovereign state and sovereignty (in the vein of Thomas Hobbes. The key component in the Hobbesian idea of sovereignty is freedom as non-interference. A sovereign state is consequently a state that is free from, i.e. not interfered with by, external actors like, for example, the EU. Put differently, either the EU is sovereign or the Member States are sovereign. By shifting the perspective to a neo-Roman republican understanding of freedom as non-domination the constitutional picture of the EU will become more nuanced. Res publica is best understood as what citizens hold in common and above their narrow self-interest. According to a republican notion of the constitution the purpose of the law is to eliminate the possibility of arbitrary domination. For that reason, not all interference is to be considered as a restriction of freedom but only those restrictions that cannot be justified according to the res publica. Viewed through the republican prism it can be argued that the EU represents an important advancement in securing freedom as non-domination without implying that the EU must become a state. The fundamental enigma can thus be rephrased as a clash between two diverging concepts of freedom. Whereas the EU will always be at odds with the idea of sovereignty (however framed it will be much easier to reconcile with the republican ideal. DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=1837332

  7. Research program on regulatory safety - Overview report 2010

    International Nuclear Information System (INIS)

    Mailaender, R

    2011-01-01

    This report for the Swiss Federal Office of Energy (SFOE) summarises the program's main points of interest, work done in the year 2010 and the results obtained. The main highlights of the research program, which was co-ordinated by the Swiss Federal Nuclear Safety Inspectorate ENSI are reported on. Topics reported on include nuclear fuels and materials, the development of a data base on damage and internal incidents, external incidents and human factors. Also, system behaviour and hazardous accident events are reported on, as are radiation protection and waste disposal. Project highlights include the KORA II project, which examined corrosion crack development in austenitic structural materials, the OECD's Halden Reactor Project in the man-technology-organisational area, and work done in the Mont Terri rock research laboratory. Also, national and international co-operation is briefly looked at and work to be done in 2011 is reviewed. A list of current and completed projects completes the report

  8. SB loca research: regulatory application and needs for the future

    International Nuclear Information System (INIS)

    Brisbois, J.; Tellier, N.

    1985-06-01

    Besides the long term safety research whose main purpose is to develop and improve safety analysis tools, the lessons learned from the TMI accident showed that the emphasis should be given on small break analysis, with multiple failures or not, to have a thorough understanding of nuclear power and decay heat removal processes in its many modes in order to develop good plant procedures. The impact of these studies on the design and on the emergency procedures, resulting from the licensing process, are described and the needs for the future are identified

  9. A complex process - transforming scientific research into regulatory rules for environmental protection

    International Nuclear Information System (INIS)

    Yan, J.J.; Goss, D.; Huffman, A.

    2002-01-01

    The protection of isolated wetlands from consumptive use withdrawals has been a policy in the South Florida Water Management District (SFWMD) for over 15 years. A guideline for protecting isolated wetlands was established in the mid-1980's for the consumptive water use permitting program administered by the SFWMD. The guideline specifies groundwater drawdown criteria associated with well field pumpage. In 1994, the SFWMD convened a panel of wetland scientists to review the existing groundwater drawdown criteria. The panel concluded there was insufficient information to determine if the criteria were either too restrictive or insufficient in protecting wetlands. The panel recommended that the SFWMD conduct research to answer related questions. Since that time, staff at the SFWMD have developed a research plan, selected 38 isolated wetland monitoring sites in seven study areas, collected over four years of data, and developed an integrated surface water and groundwater simulation model. However, the staff at the SFWMD has had difficulties in transforming the research results into regulatory rules. The nature of an isolated wetland is quite complicated. Its setting changes significantly from time to time depending on the variation of rainfall, hydro-geological conditions, and human activities. A regulatory rule requires simple and more easily measurable criteria. The regulatory staff need simple tools to evaluate many permit applications within a limited time frame. The tools used in the research process are often complicated and time consuming. This paper describes the wetland research, and the difficulties of transforming research results into regulatory rules. (author)

  10. Bibliography of reports on research sponsored by the NRC Office of Nuclear Regulatory Research, July--December 1976

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.

    1977-03-01

    A bibliography of 148 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period July through December 1976 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are sorted by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography.

  11. Bibliography of reports on research sponsored by the NRC office of nuclear regulatory research, July--December 1977

    International Nuclear Information System (INIS)

    Buchanan, J.R.

    1978-04-01

    A bibliography of 198 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period July through December 1977 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are arranged first by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography

  12. Bibliography of reports on research sponsored by the NRC Office of Nuclear Regulatory Research, July--December 1976

    International Nuclear Information System (INIS)

    Buchanan, J.R.

    1977-01-01

    A bibliography of 148 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period July through December 1976 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are sorted by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography

  13. Bibliography of reports on research sponsored by the NRC office of nuclear regulatory research, July--December 1977

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.

    1978-04-01

    A bibliography of 198 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period July through December 1977 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are arranged first by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography.

  14. Bibliography of reports on research sponsored by the NRC Office of Nuclear Regulatory Research, November 1975--June 1976

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, J.R.

    1976-09-30

    A bibliography of 152 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period November 1975 through June 1976 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are sorted by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography.

  15. Bibliography of reports on research sponsored by the NRC Office of Nuclear Regulatory Research, November 1975--June 1976

    International Nuclear Information System (INIS)

    Buchanan, J.R.

    1976-01-01

    A bibliography of 152 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period November 1975 through June 1976 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are sorted by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography

  16. Proceedings of the seminar on Leak-Before-Break: Progress in regulatory policies and supporting research

    International Nuclear Information System (INIS)

    Kashima, K.; Wilkowski, G.M.

    1988-03-01

    The third in a series of international Leak-Before-Break (LBB) Seminars supported in part by the US Nuclear Regulatory Commission was held at TEPCO Hall in the Tokyo Electric Power Company's (TEPCO) Electric Power Museum on May 14 and 15, 1987. The seminar updated the international policies and supporting research on LBB. Attendees included representatives from regulatory agencies, electric utility representatives, fabricators of nuclear power plants, research organizations, and university professors. Regulatory policy was the subject of presentations by Mr. G. Arlotto (US NRC, USA), Dr. H. Schultz (GRS, W. Germany), Dr. P. Milella (ENEA-DISP, Italy), Dr. C. Faidy, P. Jamet, and S. Bhandari (EDF/Septen, CEA/CEN, and Framatome, France), and Mr. T. Fukuzawa (MITI, Japan). Dr. F. Nilsson presented revised nondestructive inspection requirements relative to LBB in Sweden. In addition, several papers on the supporting research programs discussed regulatory policy. Questions following the presentations of the papers focused on the impact of various LBB policies or the impact of research findings. Supporting research programs were reviewed on the first and second day by several participants from the US, Japan, Germany, Canada, Italy, Sweden, England, and France

  17. Regulatory Drivers of Multimedia Reactive Nitrogen Research (Invited)

    Science.gov (United States)

    Shaw, S. L.; Knipping, E.; Kumar, N.

    2010-12-01

    The presence of nitrogenous compounds can impact biogeochemical processes in the atmosphere, oceans and freshwater, and land surfaces. As a result, a number of regulations exist that are intended to control the amount and forms of nitrogen present in the environment. These range from the newly proposed Transport Rule, both the primary and secondary National Ambient Air Quality Standards (NAAQS) for nitrogen oxide targeted at ozone and particulate matter formation and nitrogen deposition, and waterbody requirements such as the Total Maximum Daily Load. This talk will cover a subset of research activities at EPRI that inform environmental nitrogen concerns. A multimedia modeling framework has facilitated effect studies of atmospheric loadings on ecosystems. Improvements in emissions estimates, such as for mobile sources, suggest large current underestimates that will substantially impact air quality modeling of nitrogen oxides. Analyses of wintertime nitrate formation in the northern U.S. are demonstrating the roles of NH3 and NOx in particle formation there. Novel measurements of power plant stack emissions suggest operating configurations can influence the isotopic composition of emitted NOx. Novel instruments for ambient measurements of nitrogen, and suggestions for improved deposition estimates, are being developed. EPRI results suggest that multimedia solutions across multiple economic sectors, such as electrification of a wide variety of engines and water quality treatment and trading, have the potential to improve environmental quality effectively.

  18. Alternatives to animal testing: research, trends, validation, regulatory acceptance.

    Science.gov (United States)

    Huggins, Jane

    2003-01-01

    Current trends and issues in the development of alternatives to the use of animals in biomedical experimentation are discussed in this position paper. Eight topics are considered and include refinement of acute toxicity assays; eye corrosion/irritation alternatives; skin corrosion/irritation alternatives; contact sensitization alternatives; developmental/reproductive testing alternatives; genetic engineering (transgenic) assays; toxicogenomics; and validation of alternative methods. The discussion of refinement of acute toxicity assays is focused primarily on developments with regard to reduction of the number of animals used in the LD(50) assay. However, the substitution of humane endpoints such as clinical signs of toxicity for lethality in these assays is also evaluated. Alternative assays for eye corrosion/irritation as well as those for skin corrosion/irritation are described with particular attention paid to the outcomes, both successful and unsuccessful, of several validation efforts. Alternative assays for contact sensitization and developmental/reproductive toxicity are presented as examples of methods designed for the examination of interactions between toxins and somewhat more complex physiological systems. Moreover, genetic engineering and toxicogenomics are discussed with an eye toward the future of biological experimentation in general. The implications of gene manipulation for research animals, specifically, are also examined. Finally, validation methods are investigated as to their effectiveness, or lack thereof, and suggestions for their standardization and improvement, as well as implementation are reviewed.

  19. Res Publica objedinjajetsja s Sojuzom Otetshestva

    Index Scriptorium Estoniae

    2006-01-01

    Res Publica ja Isamaaliidu liitumisel tekib uus erakond - Eesti Eest!. Ida-Viru Isamaaliidu ja Res Publica esimeeste Hans Pindre, Vladislav Ponjatovski ning Narva Res Publica endise liidri Nikolai Golubevi arvamused

  20. Collective statement on the role of research in a nuclear regulatory context

    International Nuclear Information System (INIS)

    2001-01-01

    In the present context of deregulation and privatisation of the nuclear industry, maintaining an adequate level of nuclear safety research is a primary concern for nuclear regulators, researchers and nuclear power plant licensees, as well as for government officials and the public. While these different stakeholders may have common concerns and interests, there may also be differences. At the international level, it is important to understand that divisions exist both within and among countries, not only in national cultures but also in the way regulators, researchers and licensees view the rote of research. An international gathering under the auspices of the OECD Nuclear Energy Agency (NEA) took place in June 2001, bringing together heads of nuclear regulatory bodies of NEA Member countries, senior regulators, senior executives of research organisations and leaders from the nuclear industry to discuss their perceptions of the rote of research in a nuclear regulatory context. This collective statement represents an international consensus on a rationale for regulatory research for currently operating nuclear reactors and for future reactors, and sets forth specific recommendations to NEA standing technical committees and Member countries. The intended audience is primarily nuclear safety regulators, senior researchers and industry leaders. Government authorities, nuclear power plant operators and the general public may also be interested. (author)

  1. Safety research and development in relation to regulatory review in the UKAEA

    International Nuclear Information System (INIS)

    Ablitt, J.F.

    1979-01-01

    The basic functions of the regulatory review process are defined in principle, and the need for constructive interplay between regulation on the one hand and research and development on the other, in order to avoid the dangers of being over-restrictive or too permissive, is established. A number of practical examples from operating experience are quoted, which illustrate the chosen theme. (author)

  2. Trust in regulatory relations: how new insights from trust research improve regulation theory

    NARCIS (Netherlands)

    Six, F.E.

    2013-01-01

    Regulatory oversight is a key feature of public governance. This study argues - based on recent trust research - that the way in which the relation between trust and control is conceptualized in the dominant responsive regulation theory (RRT) may be improved using self determination theory (SDT).

  3. Leak-Before-Break: Further developments in regulatory policies and supporting research

    International Nuclear Information System (INIS)

    Wilkowski, G.M.; Chao, K.-S.

    1990-02-01

    The fourth in a series of international Leak-Before-Break (LBB) Seminars supported in part by the US Nuclear Regulatory Commission was held at the National Central Library in Taipei, Taiwan on May 11 and 12, 1989. The seminar updated the international polices and supporting research on LBB. Attendees included representatives from regulatory agencies, electric utilities, nuclear power plant fabricators, research organizations, and academic institutions. Regulatory policy was the subject of presentations by Mr. G. Arlotto (US NRC, USA) Dr. B. Jarman (AECB, Canada), Dr.P. Milella (ENEA-DISP, Italy), Dr. C. Faidy (EDF/Septen, France ), and Dr. K. Takumi (NUPEC, Japan). A paper by Mr. K. Wichman and Mr. A. Lee of the US NRC Office of Nuclear Reactor Regulation is included as background material to these proceedings; it discusses the history and status of LBB applications in US nuclear power plants. In addition, several papers on the supporting research programs described regulatory policy or industry standards for flaw evaluations, e.g., the ASME Section XI code procedures. Supporting research programs were reviewed on the first and second day by several participants from Taiwan, US, Japan, Canada, Italy, and France. Each individual paper has been cataloged separately

  4. Evaluation of research reactor fuel reliability in support of regulatory requirements

    International Nuclear Information System (INIS)

    Sokolov, Eugene N.

    2005-01-01

    This standards, codes and practices survey is devoted to the problem of reliability of R and D especially research reactor fuel (RRF) performance-related processes. Regulatory R and D evaluations were based on one standard and just few of them provide correlation to other relative standards whereas synthetic process approach reflects actual status of particular R and D practices. Fuel performance regulatory parameters are based on quality standards. A reliability process-based method similar to PSA/FMEA is proposed to evaluate RRF performance- related parameters in terms of reactor safety. (author)

  5. Evaluation of research reactor fuel reliability in support of regulatory requirements

    Energy Technology Data Exchange (ETDEWEB)

    Sokolov, Eugene N [Chalk River Laboratories, AECL, Chalk River, ON, K0J 1J0 (Canada)

    2005-07-01

    This standards, codes and practices survey is devoted to the problem of reliability of R and D especially research reactor fuel (RRF) performance-related processes. Regulatory R and D evaluations were based on one standard and just few of them provide correlation to other relative standards whereas synthetic process approach reflects actual status of particular R and D practices. Fuel performance regulatory parameters are based on quality standards. A reliability process-based method similar to PSA/FMEA is proposed to evaluate RRF performance- related parameters in terms of reactor safety. (author)

  6. Hypoglycemic depression of RES function.

    Science.gov (United States)

    Buchanan, B J; Filkins, J P

    1976-07-01

    The intravascular removal rates of colloidal carbon and of biologically active endotoxin by the reticuloendothelial system (RES) were evaluated as a function of blood-glucose levels. There was a significant negative correlation of carbon clearance half time on blood glucose in both saline-treated and insulin-treated rats. Insulin hypoglycemia depressed RES carbon clearance with the maximal effect occurring at blood glucose values below 30 mg/dl. Insulin hypoglycemia also severely impaired the intravascular removal of endotoxin as evaluated by lethality bioassay in lead-sensitized rats. It is concluded that blood glucose may modulate RES phagocytic function and that the hypoglycemia of endotoxin shock may augment the shock state due to impairment of RES host defense clearance functions.

  7. Reactor safety research program. A description of current and planned reactor safety research sponsored by the Nuclear Regulatory Commission's Division of Reactor Safety Research

    International Nuclear Information System (INIS)

    1975-06-01

    The reactor safety research program, sponsored by the Nuclear Regulatory Commission's Division of Reactor Safety Research, is described in terms of its program objectives, current status, and future plans. Elements of safety research work applicable to water reactors, fast reactors, and gas cooled reactors are presented together with brief descriptions of current and planned test facilities. (U.S.)

  8. NRC safety research in support of regulation - FY 1994. Volume 9

    International Nuclear Information System (INIS)

    1995-06-01

    This report, the tenth in a series of annual reports, was prepared in response to congressional inquiries concerning how nuclear regulatory research is used. It summarizes the accomplishments of the Office of Nuclear Regulatory Research during FY 1994. The goal of the Office of Nuclear Regulatory Research (RES) is to ensure the availability of sound technical bases for timely rulemaking and related decisions in support of NRC regulatory/licensing/inspection activities. RES also has responsibilities related to the resolution of generic safety issues and to the review of licensee submittals regarding individual plant examinations. It is the responsibility of RES to conduct the NRC's rulemaking process, including the issuance of regulatory guides and rules that govern NRC licensed activities

  9. The U.S. Nuclear Regulatory Commission seismic safety research program

    International Nuclear Information System (INIS)

    Kenneally, R.M.; Guzy, D.J.; Murphy, A.J.

    1988-01-01

    The seismic safety research program sponsored by the U.S. Nuclear Regulatory Commission is directed toward improving the evaluation of potential earthquake effects on nuclear power plant operations. The research has been divided into three major program areas: earth sciences, seismic design margins, and fragilities and response. A major thrust of this research is to assess plant behavior for seismic events more severe and less probable than those considered in design. However, there is also research aimed at improving the evaluation of earthquake input and plant response at plant design levels

  10. Global regulatory developments for clinical stem cell research: diversification and challenges to collaborations.

    Science.gov (United States)

    Rosemann, Achim; Bortz, Gabriela; Vasen, Federico; Sleeboom-Faulkner, Margaret

    2016-10-01

    In this article, we explore regulatory developments in stem cell medicine in seven jurisdictions: Japan, China, India, Argentina, Brazil, the USA and the EU. We will show that the research methods, ethical standards and approval procedures for the market use of clinical stem cell interventions are undergoing an important process of global diversification. We will discuss the implications of this process for international harmonization and the conduct of multicountry clinical research collaborations. It will become clear that the increasing heterogeneity of research standards and regulations in the stem cell field presents a significant challenge to international clinical trial partnerships, especially with countries that diverge from the regulatory models that have been developed in the USA and the EU.

  11. Res Publica v respublike / Roman Gornev

    Index Scriptorium Estoniae

    Gornev, Roman

    2002-01-01

    Järg 29. november nr. 48 lk. 7. Res Publica - uue poliitika partei. Res Publica Ida-Virumaal, partei juhtfiguurid, Res Publica Kohtla-Järvel. Koalitsioonileping Keskerakonnaga viis konfliktini partei juhtkonnaga. Kohtla-Järve Res Publica kohaliku organisatsiooni konflikti partei juhtkonnaga kommenteerib Hants Hint

  12. Res Publica kogub uut hoogu / Andres Jalak

    Index Scriptorium Estoniae

    Jalak, Andres, 1953-

    2005-01-01

    Kommenteerides Res Publica senise esimehe ja endise peaministri Juhan Partsi ning uueks esimeheks valitud Taavi Veskimäe kõnet Res Publica üldkogul, väljendab Res Publica fraktsiooni aseesimees usku, et Res Publica juhtimisel suudetakse 2007. aasta parlamendivalimistel taastada tulevikku suunatud mõtlemisega valitsus

  13. Barred from better medicine? Reexamining regulatory barriers to the inclusion of prisoners in research.

    Science.gov (United States)

    Huang, Elaine; Cauley, Jacqueline; Wagner, Jennifer K

    2017-04-01

    In 2015, President Obama announced plans for the Precision Medicine Initiative ® (PMI), an ambitious longitudinal project aimed at revolutionizing medicine. Integral to this Initiative is the recruitment of over one million Americans into a volunteer research cohort, the All of Us SM Research Program. The announcement has generated much excitement but absent is a discussion of how the All of Us Research Program-to be implemented within the context of social realities of mass incarcerations and racial disparities in criminal justice and healthcare-might excaberate health disparities. We examine how attainment of Initiative's stated goals of reflecting the diversity of the American population and including all who are interested in participating might be impeded by regulatory and administrative barriers to the involvement of participants who become incarcerated during longitudinal studies. Changes have been proposed to the federal policy for human subjects research protections, but current regulations and administrative policies-developed under a protectionist paradigm in response to scandalous research practices with confined populations-dramatically limit research involving prisoners. Our review provides rationale for the development of Initiative policies that anticipate recruitment and retention obstacles that might frustrate inclusivity and exacerbate health disparities. Furthermore, we question the effective ban on biomedical and behavioral research involving prisoners and advocate for regulatory reforms that restore participatory research rights of prisoners. Disparities in health and justice are intertwined, and without regulatory reforms to facilitate participatory research rights of prisoners and careful planning of viable and responsible recruitment, engagement, and retention strategies, Initiative could miss discovery opportunities, exacerbate health disparities, and increase levels of distrust in science.

  14. Collaborative international research: ethical and regulatory issues pertaining to human biological materials at a South African institutional research ethics committee.

    Science.gov (United States)

    Sathar, Aslam; Dhai, Amaboo; van der Linde, Stephan

    2014-12-01

    Human Biological Materials (HBMs) are an invaluable resource in biomedical research. To determine if researchers and a Research Ethics Committee (REC) at a South African institution addressed ethical issues pertaining to HBMs in collaborative research with developed countries. Ethically approved retrospective cross-sectional descriptive audit. Of the 1305 protocols audited, 151 (11.57%) fulfilled the study's inclusion criteria. Compared to other developed countries, a majority of sponsors (90) were from the USA (p = 0.0001). The principle investigators (PIs) in all 151 protocols informed the REC of their intent to store HBMs. Only 132 protocols informed research participants (P ethical and regulatory issues pertaining to HBMs. There was a lack of congruence between the ethical guidelines of developed countries and their actions which are central to the access to HBMs in collaborative research. HBMs may be leaving South Africa without EPs and MTAs during the process of international collaborative research. © 2013 John Wiley & Sons Ltd.

  15. Current role of the USNRC safety research program in support of the regulatory process

    International Nuclear Information System (INIS)

    Levine, S.

    1979-01-01

    The current role of the USNRC's safety research program is shown. Some aspects of this role in the wake of the TMI accident are discused as well as some historical perspective on the development of USNRC's program, its relationship with the NRC mission, an overview of the program activities and some recent research results, and finally the impact of the TMI accident in clarifiying needs for expedited and new research activities, including the need for a greatly enhanced use of probabilistic analysis techniques to improve the coherence of its regulatory process. (author)

  16. Res Cover Oct 07

    Indian Academy of Sciences (India)

    space, independent of wind-induced rotation of the balloon clusters. ... facilities built up at the TIFR, presented a unique combination for research on many other basic ... The several hundred particles created in our event were incompatible.

  17. Regulatory activities and their research and development support in the CSSR

    International Nuclear Information System (INIS)

    Klik, F.; Kriz, Z.

    1977-01-01

    According to the existing laws the Czechoslovak Atomic Energy Commission (CSAEC) is authorized to regulate the Czechoslovak nuclear activities with respect to the nuclear safety, waste management and accountability and control of nuclear materials. Its activity with respect to nuclear safety consists mainly of: preparation of safety code of practices supplemented by safety guides for nuclear facilities, assessment of nuclear safety and issuing of binding opinion on nuclear safety for licensing of nuclear facilities, inspection of nuclear safety during construction and operation of nuclear facilities. The first part of the paper deals with the regulatory implementation. This covers the first stage specified by the construction and operation of research reactors only, the second stage specified by the design, construction, commissioning and operation of the first prototype nuclear power plant and the present stage specified by the construction and commissioning of a number of industrially developed nuclear power reactors. The present stage of regulatory implementation is described in detail. This covers the development of regulatory documentation such as safety code of practices and safety guides and the main safety requirements included in the existing safety code of practices for the siting, design and operation of nuclear power plants equipped with pressure water reactors. Then the general licensing procedures and organization including the structure and contents of safety documentation required for the licensing of siting, construction and operation of nuclear power plants is also described. The paper deals also with the inspection practices applied during construction, commissioning and operation of nuclear power plant in order to verify that the licensing conditions and requirements are fulfilled. The paper gives also some basic information about coordination of CSAEC nuclear safety regulatory activity with the regulatory activities of other governmental bodies

  18. Regulatory research and support program for 1993/1994 - project descriptions

    International Nuclear Information System (INIS)

    1993-01-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend the Atomic Energy Control Board's regulatory program beyond the capability of in-house resources. The overall objective of the research and support program is to produce pertinent and independent information that will assist the Board and its staff in making sound, timely and credible decisions on regulating nuclear facilities and materials. The program is divided into nine main areas of research (mission objects) covering the safety of nuclear facilities, radioactive waste management, health physics, physical security, the development of regulatory processes, and special services. In addition, for the first time in this year's program, sub-programs (collections of related projects) have been organized in some areas of study; these sub-programs may cut across several mission objects. More sub-programs will be introduced in future years. A total of 96 projects are planned for 1993/94, including a number which are ongoing from the previous fiscal year. Projects that are held in reserve in case funding becomes available are also listed and provisionally ranked. The spending estimates for the RSP were calculated on the basis of an expected budget of $3.85 M

  19. Regulatory research and support program for 1993/1994 - project descriptions

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-03-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend the Atomic Energy Control Board`s regulatory program beyond the capability of in-house resources. The overall objective of the research and support program is to produce pertinent and independent information that will assist the Board and its staff in making sound, timely and credible decisions on regulating nuclear facilities and materials. The program is divided into nine main areas of research (mission objects) covering the safety of nuclear facilities, radioactive waste management, health physics, physical security, the development of regulatory processes, and special services. In addition, for the first time in this year`s program, sub-programs (collections of related projects) have been organized in some areas of study; these sub-programs may cut across several mission objects. More sub-programs will be introduced in future years. A total of 96 projects are planned for 1993/94, including a number which are ongoing from the previous fiscal year. Projects that are held in reserve in case funding becomes available are also listed and provisionally ranked. The spending estimates for the RSP were calculated on the basis of an expected budget of $3.85 M.

  20. Res Jan 08 Print

    Indian Academy of Sciences (India)

    effectively promoted Neurospora as an experimental organism, ... research program, as an Emeritus Professor “recalled to active duty,” after his official ... Perkins' guidance on basic Neurospora genetics methodology. Several of ... Perkins was a true .... colonies into separate sterile envelopes, 7–10 samples from each site.

  1. Ethics and Regulatory Challenges and Opportunities in Patient-Centered Comparative Effectiveness Research.

    Science.gov (United States)

    Sugarman, Jeremy

    2016-04-01

    The Affordable Care Act includes provisions for the conduct of large-scale, patient-centered comparative effectiveness research. Such efforts aim toward the laudable moral goal of having evidence to improve health care decision making. Nevertheless, these pragmatic clinical research efforts that typically pose minimal incremental risk and are enmeshed in routine care settings perhaps surprisingly encounter an array of ethics and regulatory challenges and opportunities for academic health centers. An emphasis on patient-centeredness forces an examination of the appropriateness of traditional methods used to protect the rights, interests, and welfare of participants. At the same time, meaningful collaboration with patients throughout the research process also necessitates ensuring that novel approaches to research (including recruitment and consent) entail necessary protections regarding such issues as privacy. As the scientific and logistical aspects of this research are being developed, substantial attention is being focused on the accompanying ethics and regulatory issues that have emerged, which should help to facilitate ethically appropriate research in a variety of contexts.

  2. Meta-Analysis of Single-Case Design Research on Self-Regulatory Interventions for Academic Performance

    Science.gov (United States)

    Perry, Valerie; Albeg, Loren; Tung, Catherine

    2012-01-01

    The current study examined the effects of self-regulatory interventions on reading, writing, and math by conducting a meta-analysis of single-case design research. Self-regulatory interventions have promise as an effective approach that is both minimally invasive and involves minimal resources. Effects of the interventions were analyzed by…

  3. Review of regulatory requirements relevant to calibration of monitoring instruments in research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Gomaa, Hassan; Khedr, Ahmed; El-Din Talha, Kamal [Egyptian Nuclear and Radiological Regulatory Authority, Cairo (Egypt). Nuclear Safety Engineering Dept.

    2015-05-15

    The objective of this work is to demonstrate the regulatory requirements pertaining to calibration of monitoring instruments in research reactors. The regulatory statements concerning this subject in IAEA safety standards and the implementation of such regulations in twelve countries with different levels of nuclear programs are surveyed: Australia, Bulgaria, Canada, Egypt, Finland, Germany, Hungary, Slovenia, South Korea, Spain, United Kingdom of England and United States of America. In addition, the requirements of ISO/IEC17025 and NUPIC (Nuclear Utilities Procurement Issues Committee) are compared. Seven technical and administrate aspects are suggested as the comparison criteria and the explicit expression of the statements, the level of document (i.e.: act, requirement or guide) are the considered resources. The main differences and similarities between the different approaches are identified in order to provide an input for future development of the national regulations.

  4. Training related research and development conducted at Oak Ridge National Laboratory for the US Nuclear Regulatory Commission

    International Nuclear Information System (INIS)

    Haas, P.M.

    1985-01-01

    For a number of years Oak Ridge National Laboratory (ORNL) has conducted a sizeable program of human factors research and development in support of the Office of Nuclear Regulatory Research of the US Nuclear Regulatory Commission (NRC). The history of this effort has in many ways paralleled the growth of human factors R and D throughout the nuclear industry and the program has contributed to advances in the industry as well as to NRC regulatory and research programs. This paper reviews the major projects and products of the program relevant to training and concludes with an identification of future R and D needs

  5. BioMagResBank.

    NARCIS (Netherlands)

    Ulrich, E.L.; Akutsu, H.; Doreleijers, J.; Harano, Y.; Ioannidis, Y.E.; Lin, J.; Livny, M.; Mading, S.; Maziuk, D.; Miller, Z.; Nakatani, E.; Schulte, C.F.; Tolmie, D.E.; Wenger, R.K.; Yao, H.; Markley, J.L.

    2008-01-01

    The BioMagResBank (BMRB: www.bmrb.wisc.edu) is a repository for experimental and derived data gathered from nuclear magnetic resonance (NMR) spectroscopic studies of biological molecules. BMRB is a partner in the Worldwide Protein Data Bank (wwPDB). The BMRB archive consists of four main data

  6. Resúmenes Conferencias Magistrales

    Directory of Open Access Journals (Sweden)

    Editor Gabriel Vargas Arana

    2015-12-01

    Full Text Available En este artículo se pueden encontrar los resúmenes de las conferencias magistrales del III Congreso Latinoamericano de Plantas Medicinales, desarrollado del 12 al 14 de agosto de 2015 en la ciudad de Iquitos, Perú.

  7. Resúmenes Presentaciones Orales

    Directory of Open Access Journals (Sweden)

    Editor Gabriel Vargas Arana

    2015-12-01

    Full Text Available En este artículo se pueden encontrar los resúmenes de las presentaciones orales del III Congreso Latinoamericano de Plantas Medicinales, desarrollado del 12 al 14 de agosto de 2015 en la ciudad de Iquitos, Perú.

  8. RES: Regularized Stochastic BFGS Algorithm

    Science.gov (United States)

    Mokhtari, Aryan; Ribeiro, Alejandro

    2014-12-01

    RES, a regularized stochastic version of the Broyden-Fletcher-Goldfarb-Shanno (BFGS) quasi-Newton method is proposed to solve convex optimization problems with stochastic objectives. The use of stochastic gradient descent algorithms is widespread, but the number of iterations required to approximate optimal arguments can be prohibitive in high dimensional problems. Application of second order methods, on the other hand, is impracticable because computation of objective function Hessian inverses incurs excessive computational cost. BFGS modifies gradient descent by introducing a Hessian approximation matrix computed from finite gradient differences. RES utilizes stochastic gradients in lieu of deterministic gradients for both, the determination of descent directions and the approximation of the objective function's curvature. Since stochastic gradients can be computed at manageable computational cost RES is realizable and retains the convergence rate advantages of its deterministic counterparts. Convergence results show that lower and upper bounds on the Hessian egeinvalues of the sample functions are sufficient to guarantee convergence to optimal arguments. Numerical experiments showcase reductions in convergence time relative to stochastic gradient descent algorithms and non-regularized stochastic versions of BFGS. An application of RES to the implementation of support vector machines is developed.

  9. XSpRES

    DEFF Research Database (Denmark)

    Mainka, Christian; Jensen, Meiko; Iacono, Luigi Lo

    2012-01-01

    XML Encryption and XML Signature are fundamental security standards forming the core for many applications which require to process XML-based data. Due to the increased usage of XML in distributed systems and platforms such as in SOA and Cloud settings, the demand for robust and effective security...... mechanisms increased as well. Recent research work discovered, however, substantial vulnerabilities in these standards as well as in the vast majority of the available implementations. Amongst them, the so-called XML Signature Wrapping attack belongs to the most relevant ones. With the many possible...... instances of this attack type, it is feasible to annul security systems relying on XML Signature and to gain access to protected resources as has been successfully demonstrated lately for various Cloud infrastructures and services. This paper contributes a comprehensive approach to robust and effective XML...

  10. Drinking Water Research Division's research activities in support of EPA's regulatory agenda

    International Nuclear Information System (INIS)

    Clark, R.M.; Feige, W.A.

    1991-01-01

    The Safe Drinking Water Act and its Amendments will have a dramatic impact on the way in which one views the treatment and distribution of water in the U.S. The paper discusses the regulatory agenda, including proposed and promulgated regulations for volatile and synthetic organic contaminants, pesticides, lead, copper, inorganic contaminants, and radionuclides. In addition, the Surface Water Treatment and Coliform Rules are discussed in some detail. Tables are presented that list the Maximum Contaminant Levels (MCLs) and Maximum Contaminant Level Goals (MCLGs), as well as Best Available Technology (BAT) for reducing many of these contaminants to acceptable levels. Finally, a discussion of expected disinfection requirements and the regulation of disinfection by-products (DBP) is made. Treatment techniques for controlling DBPs are briefly described

  11. Villain of Molecular Biology: Why are we not reproducible in research? [v1; ref status: indexed, http://f1000r.es/5ou

    Directory of Open Access Journals (Sweden)

    Vikash Bhardwaj

    2015-07-01

    Full Text Available Worldwide, there is an issue of irreproducibility in life science research. In the USA alone $28 billion per year spent on preclinical research is not reproducible. Within this opinion article, I provide a brief historical account of the discovery of the Watson-Crick DNA model and introduce another neglected model of DNA. This negligence may be one of the fundamental reasons behind irreproducibility in molecular biology research.

  12. Global Regulatory T-Cell Research from 2000 to 2015: A Bibliometric Analysis.

    Directory of Open Access Journals (Sweden)

    Yin Zongyi

    Full Text Available We aimed to analyze the global scientific output of regulatory T-cell (Treg research and built a model to qualitatively and quantitatively evaluate publications from 2000 to 2015. Data were obtained from the Web of Science Core Collection (WoSCC of Thomson Reuters on January 1, 2016. The bibliometric method and Citespace III were used to analyze authors, journals, publication outputs, institutions, countries, research areas, research hotspots, and trends. In total, we identified 35,741 publications on Treg research from 2000 to 2015, and observed that the annual publication rate increased with time. The Journal of Immunology published the highest number of articles, the leading country was the USA, and the leading institute was Harvard University. Sakaguchi, Hori, Fontenot, and Wang were the top authors in Treg research. Immunology accounted for the highest number of publications, followed by oncology, experimental medicine, cell biology, and hematology. Keyword analysis indicated that autoimmunity, inflammation, cytokine, gene expression, foxp3, and immunotherapy were the research hotspots, whereas autoimmune inflammation, gene therapy, granzyme B, RORγt, and th17 were the frontiers of Treg research. This bibliometric analysis revealed that Treg-related studies are still research hotspots, and that Treg-related clinical therapies are the research frontiers; however, further study and collaborations are needed worldwide. Overall, our findings provide valuable information for the editors of immunology journals to identify new perspectives and shape future research directions.

  13. A brief review of recent Charcot-Marie-Tooth research and priorities [v1; ref status: indexed, http://f1000r.es/53g

    Directory of Open Access Journals (Sweden)

    Sean Ekins

    2015-02-01

    Full Text Available This brief review of current research progress on Charcot-Marie-Tooth (CMT disease is a summary of discussions initiated at the Hereditary Neuropathy Foundation (HNF scientific advisory board meeting on November 7, 2014. It covers recent published and unpublished in vitro and in vivo research. We discuss recent promising preclinical work for CMT1A, the development of new biomarkers, the characterization of different animal models, and the analysis of the frequency of gene mutations in patients with CMT. We also describe how progress in related fields may benefit CMT therapeutic development, including the potential of gene therapy and stem cell research. We also discuss the potential to assess and improve the quality of life of CMT patients. This summary of CMT research identifies some of the gaps which may have an impact on upcoming clinical trials. We provide some priorities for CMT research and areas which HNF can support. The goal of this review is to inform the scientific community about ongoing research and to avoid unnecessary overlap, while also highlighting areas ripe for further investigation. The general collaborative approach we have taken may be useful for other rare neurological diseases.

  14. Mida ootame Res Publica poliitikutelt? / Andreas Kaju

    Index Scriptorium Estoniae

    Kaju, Andreas

    2003-01-01

    Res Publica Juventus on piirkondadele saadetud küsitlustega otsinud vastuseid mitmetele probleemidele. Eesmärk Res Publica poliitilise käitumise raamide määramine. Tabel: Juventuse küsimused piirkondadele

  15. Rahvaliit likvideerib Res Publica veeuputust / Janno Reiljan

    Index Scriptorium Estoniae

    Reiljan, Janno, 1951-2018

    2005-01-01

    Ilmunud ka: Molodjozh Estonii 1. august lk. 5. Selgitused Res Publica esimehe Taavi Veskimägi artiklile 25. juuli Postimehes "Pärast meid tulgu või veeuputus". Res Publica ja Rahvaliidu poliitika võrdlus

  16. Miks Res Publica kaotas / Juhan Parts

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 29. juuni 2004, lk. 2; Koit, 29. juuni 2004, lk. 6. Europarlamendi valimiste tulemused erakonnale Res Publica. Juhan Partsi kõne 26. juunil Pärnus toimunud Res Publica volikogul. Lühendatult

  17. Padenije Res Publica / Viktoria Jürmann

    Index Scriptorium Estoniae

    Jürmann, Viktoria

    2005-01-01

    Res Publica üks rajajatest, Rein Taagepera, lahkus parteist, süüdistades erakonda paremtsentristlikust maailmavaatest loobumises. Res Publica Riigikogu fraktsioon tahab avaldada umbusaldust haridus- ja teadusminister Mailis Repsile

  18. Res Publica esitas avalduse kaposse / Virkko Lepassalu

    Index Scriptorium Estoniae

    Lepassalu, Virkko, 1971-

    2003-01-01

    Kaposse jõudis Res Publica avaldus, milles palutakse uurida erakonda seadusvastaselt anonüümselt sponsoreerima kutsuva kirja tagamaid. Vt. ka Äripäev 19. veebruar lk. 6 "Kapo ei alustanud Res Publica avalduse peale kriminaalmenetlust"

  19. Rein Taagepera lahkub Res Publicast / Kristjan Roos

    Index Scriptorium Estoniae

    Roos, Kristjan, 1978-

    2005-01-01

    Res Publica asutaja Rein Taagepera, Jaan Einasto, Mare Taagepera ja Lauri Aaspõllu lahkuvad Res Publicast, kuna erakond on nende väitel muutunud paremtsentrist paremäärmuslikuks. Vt. samas: Erakonnad hoiavad uksed valla

  20. Collaboration for rare disease drug discovery research [v1; ref status: indexed, http://f1000r.es/4l6

    Directory of Open Access Journals (Sweden)

    Nadia K. Litterman

    2014-10-01

    Full Text Available Rare disease research has reached a tipping point, with the confluence of scientific and technologic developments that if appropriately harnessed, could lead to key breakthroughs and treatments for this set of devastating disorders. Industry-wide trends have revealed that the traditional drug discovery research and development (R&D model is no longer viable, and drug companies are evolving their approach. Rather than only pursue blockbuster therapeutics for heterogeneous, common diseases, drug companies have increasingly begun to shift their focus to rare diseases. In academia, advances in genetics analyses and disease mechanisms have allowed scientific understanding to mature, but the lack of funding and translational capability severely limits the rare disease research that leads to clinical trials. Simultaneously, there is a movement towards increased research collaboration, more data sharing, and heightened engagement and active involvement by patients, advocates, and foundations. The growth in networks and social networking tools presents an opportunity to help reach other patients but also find researchers and build collaborations. The growth of collaborative software that can enable researchers to share their data could also enable rare disease patients and foundations to manage their portfolio of funded projects for developing new therapeutics and suggest drug repurposing opportunities. Still there are many thousands of diseases without treatments and with only fragmented research efforts. We will describe some recent progress in several rare diseases used as examples and propose how collaborations could be facilitated. We propose that the development of a center of excellence that integrates and shares informatics resources for rare diseases sponsored by all of the stakeholders would help foster these initiatives.

  1. agINFRA: a research data hub for agriculture, food and the environment [v2; ref status: indexed, http://f1000r.es/5hk

    Directory of Open Access Journals (Sweden)

    Andreas Drakos

    2015-06-01

    Full Text Available The agINFRA project (www.aginfra.eu was a European Commission funded project under the 7th Framework Programme that aimed to introduce agricultural scientific communities to the vision of open and participatory data-intensive science. agINFRA has now evolved into the European hub for data-powered research on agriculture, food and the environment, serving the research community through multiple roles. Working on enhancing the interoperability between heterogeneous data sources, the agINFRA project has left a set of grid- and cloud- based services that can be reused by future initiatives and adopted by existing ones, in order to facilitate the dissemination of agricultural research, educational and other types of data. On top of that, agINFRA provided a set of domain-specific recommendations for the publication of agri-food research outcomes. This paper discusses the concept of the agINFRA project and presents its major outcomes, as adopted by existing initiatives activated in the context of agricultural research and education.

  2. PWR and BWR anticipated and abnormal plant transient research sponsored by the US Nuclear Regulatory Commission

    International Nuclear Information System (INIS)

    Beckner, W.D.; Sullivan, L.H.

    1984-01-01

    This chapter reviews the regulatory activities of the US NRC since the realization that anticipated transients with multiple failures (including operator actions) are the major contributors to risk from reactor operations and that the low probability design basis accidents (DBA) are relatively small contributors to risk. The Three Mile Island-2 accident demonstrated that anticipated transients, combined with multiple equipment and/or operator failures, can result in significant core damage. Topics considered include research in direct response to Three Mile Island-2, research in response to specific safety issues, and research to improve the overall understanding of transients (experimental facilities, computer codes). It is concluded that the US NRC has made significant progress in improving its ability to analyze and evaluate abnormal and anticipated transients

  3. Resources, challenges and way forward in rare mitochondrial diseases research [v1; ref status: indexed, http://f1000r.es/54x

    Directory of Open Access Journals (Sweden)

    Anshu Bhardwaj

    2015-03-01

    Full Text Available Over 300 million people are affected by about 7000 rare diseases globally. There are tremendous resource limitations and challenges in driving research and drug development for rare diseases. Hence, innovative approaches are needed to identify potential solutions. This review focuses on the resources developed over the past years for analysis of genome data towards understanding disease biology especially in the context of mitochondrial diseases, given that mitochondria are central to major cellular pathways and their dysfunction leads to a broad spectrum of diseases. Platforms for collaboration of research groups, clinicians and patients and the advantages of community collaborative efforts in addressing rare diseases are also discussed. The review also describes crowdsourcing and crowdfunding efforts in rare diseases research and how the upcoming initiatives for understanding disease biology including analyses of large number of genomes are also applicable to rare diseases.

  4. Resources, challenges and way forward in rare mitochondrial diseases research [v2; ref status: indexed, http://f1000r.es/5r6

    Directory of Open Access Journals (Sweden)

    Neeraj Kumar Rajput

    2015-08-01

    Full Text Available Over 300 million people are affected by about 7000 rare diseases globally. There are tremendous resource limitations and challenges in driving research and drug development for rare diseases. Hence, innovative approaches are needed to identify potential solutions. This review focuses on the resources developed over the past years for analysis of genome data towards understanding disease biology especially in the context of mitochondrial diseases, given that mitochondria are central to major cellular pathways and their dysfunction leads to a broad spectrum of diseases. Platforms for collaboration of research groups, clinicians and patients and the advantages of community collaborative efforts in addressing rare diseases are also discussed. The review also describes crowdsourcing and crowdfunding efforts in rare diseases research and how the upcoming initiatives for understanding disease biology including analyses of large number of genomes are also applicable to rare diseases.

  5. DataUp: A tool to help researchers describe and share tabular data [v2; ref status: indexed, http://f1000r.es/48u

    Directory of Open Access Journals (Sweden)

    Carly Strasser

    2014-09-01

    Full Text Available Scientific datasets have immeasurable value, but they lose their value over time without proper documentation, long-term storage, and easy discovery and access. Across disciplines as diverse as astronomy, demography, archeology, and ecology, large numbers of small heterogeneous datasets (i.e., the long tail of data are especially at risk unless they are properly documented, saved, and shared. One unifying factor for many of these at-risk datasets is that they reside in spreadsheets. In response to this need, the California Digital Library (CDL partnered with Microsoft Research Connections and the Gordon and Betty Moore Foundation to create the DataUp data management tool for Microsoft Excel. Many researchers creating these small, heterogeneous datasets use Excel at some point in their data collection and analysis workflow, so we were interested in developing a data management tool that fits easily into those work flows and minimizes the learning curve for researchers. The DataUp project began in August 2011. We first formally assessed the needs of researchers by conducting surveys and interviews of our target research groups: earth, environmental, and ecological scientists. We found that, on average, researchers had very poor data management practices, were not aware of data centers or metadata standards, and did not understand the benefits of data management or sharing. Based on our survey results, we composed a list of desirable components and requirements and solicited feedback from the community to prioritize potential features of the DataUp tool. These requirements were then relayed to the software developers, and DataUp was successfully launched in October 2012.

  6. Drosophila's contribution to stem cell research [v1; ref status: indexed, http://f1000r.es/5h7

    Directory of Open Access Journals (Sweden)

    Gyanesh Singh

    2015-06-01

    Full Text Available The discovery of Drosophila stem cells with striking similarities to mammalian stem cells has brought new hope for stem cell research. A recent development in Drosophila stem cell research is bringing wider opportunities for contemporary stem cell biologists. In this regard, Drosophila germ cells are becoming a popular model of stem cell research. In several cases, genes that controlled Drosophila stem cells were later discovered to have functional homologs in mammalian stem cells. Like mammals, Drosophila germline stem cells (GSCs are controlled by both intrinsic as well as external signals. Inside the Drosophila testes, germline and somatic stem cells form a cluster of cells (the hub. Hub cells depend on JAK-STAT signaling, and, in absence of this signal, they do not self-renew. In Drosophila, significant changes occur within the stem cell niche that contributes to a decline in stem cell number over time. In case of aging Drosophila, somatic niche cells show reduced DE-cadherin and unpaired (Upd proteins. Unpaired proteins are known to directly decrease stem cell number within the niches, and, overexpression of upd within niche cells restored GSCs in older males also . Stem cells in the midgut of Drosophila are also very promising. Reduced Notch signaling was found to increase the number of midgut progenitor cells. On the other hand, activation of the Notch pathway decreased proliferation of these cells. Further research in this area should lead to the discovery of additional factors that regulate stem and progenitor cells in Drosophila.

  7. 10 teesi Res Publica valitsemisprogrammist aastani 2007

    Index Scriptorium Estoniae

    2004-01-01

    Ilmunud ka: Ottshjot narodu Estonii. Res Publica 2003, 2004, lk. 4-5, 8-9. Res Publica valitsemisprogrammi lubadustest ja täitmisest. Vt. lk. 8-9 Res Publica ministrite olulisemad tegevused 2004. aastal - lühiülevaate teevad Ken-Marti Vaher, Taavi Veskimägi, Marko Pomerants, Toivo Maimets

  8. Shaping the Future of Research: a perspective from junior scientists [v2; ref status: indexed, http://f1000r.es/4yc

    Directory of Open Access Journals (Sweden)

    Gary S. McDowell

    2015-01-01

    Full Text Available The landscape of scientific research and funding is in flux as a result of tight budgets, evolving models of both publishing and evaluation, and questions about training and workforce stability. As future leaders, junior scientists are uniquely poised to shape the culture and practice of science in response to these challenges. A group of postdocs in the Boston area who are invested in improving the scientific endeavor, planned a symposium held on October 2nd and 3rd, 2014, as a way to join the discussion about the future of US biomedical research. Here we present a report of the proceedings of participant-driven workshops and the organizers’ synthesis of the outcomes.

  9. Confronting Ethical and Regulatory Challenges of Emergency Care Research With Conscious Patients.

    Science.gov (United States)

    Dickert, Neal W; Brown, Jeremy; Cairns, Charles B; Eaves-Leanos, Aaliyah; Goldkind, Sara F; Kim, Scott Y H; Nichol, Graham; O'Conor, Katie J; Scott, Jane D; Sinert, Richard; Wendler, David; Wright, David W; Silbergleit, Robert

    2016-04-01

    Barriers to informed consent are ubiquitous in the conduct of emergency care research across a wide range of conditions and clinical contexts. They are largely unavoidable; can be related to time constraints, physical symptoms, emotional stress, and cognitive impairment; and affect patients and surrogates. US regulations permit an exception from informed consent for certain clinical trials in emergency settings, but these regulations have generally been used to facilitate trials in which patients are unconscious and no surrogate is available. Most emergency care research, however, involves conscious patients, and surrogates are often available. Unfortunately, there is neither clear regulatory guidance nor established ethical standards in regard to consent in these settings. In this report-the result of a workshop convened by the National Institutes of Health Office of Emergency Care Research and Department of Bioethics to address ethical challenges in emergency care research-we clarify potential gaps in ethical understanding and federal regulations about research in emergency care in which limited involvement of patients or surrogates in enrollment decisions is possible. We propose a spectrum of approaches directed toward realistic ethical goals and a research and policy agenda for addressing these issues to facilitate clinical research necessary to improve emergency care. Copyright © 2015 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

  10. A report to Congress Nuclear Regulatory Research: Project descriptions for FY88

    International Nuclear Information System (INIS)

    1988-08-01

    This report has been written in response to a request of the United States Congress that the Nuclear Regulatory Commission prepare and submit to the Congress a summary description of its research projects. Commercial contracts and research efforts at the Department of Energy (DOE) laboratories are assigned a five-digit financial number (FIN). This report provides a project descriptions for each FIN number. The project descriptions are divided into five major sections called program areas. These areas are: integrity of reactor components, prevent damage to reactor cores, reactor containment safety, confirming safety of nuclear waste disposal, and resolving safety issues and developing regulations. An explanation of each program area is given in an overview at the beginning of each section

  11. Geothermal industry position paper: EPA regulatory options and research and development information needs

    Energy Technology Data Exchange (ETDEWEB)

    D' Alessio, G.

    1977-08-01

    The environmental impact of geothermal energy development may be less intense or widespread than that of some other energy sources; however, it is the first example of a number of emerging energy technologies that must be dealt with by EPA. EPA may consider a spectrum of options ranging from a posutre of business as usual to one of immediate setting of standards, as favored by ERDA. The paper discusses the regulatory approaches and the potential problems that geothermal energy may present in the areas of air quality, water quality, and other impacts. It is recommended that a coordinated program of research be drawn up, comprised of specific research projects, the types of geothermal resource to which they apply, and the date by which the information is required.

  12. Geothermal Industry Position Paper: EPA Regulatory Options and Research and Development Information Needs

    Energy Technology Data Exchange (ETDEWEB)

    Swetnam, G.F.

    1976-11-01

    The environmental impact of geothermal energy development may be less intense or widespread than that of some other energy sources; however, it is the first example of a number of emerging energy technologies that must be dealt with by EPA. EPA may consider a spectrum of options ranging from a posture of business as usual to one of immediate setting of standards, as favored by ERDA. The paper discusses the regulatory approaches and the potential problems that geothermal energy may present in the areas of air quality, water quality, and other impacts. It is recommended that a coordinated program of research be drawn up, comprised of specific research projects, the types of geothermal resource to which they apply, and the date by which the information is required.

  13. 23 mai 2008 - Madame Micheline Calmy-Rey Conseillère fédérale, Cheffe du Département fédéral des affaires étrangères (DFAE), Confédération suisse et Dr Annette Schavan, Federal Minister of Education and Research, Germany visitent le CERN

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    23 mai 2008 - Madame Micheline Calmy-Rey Conseillère fédérale, Cheffe du Département fédéral des affaires étrangères (DFAE), Confédération suisse et Dr Annette Schavan, Federal Minister of Education and Research, Germany visitent le CERN

  14. The Response Regulator ResD Plays a Role in Metabolism of Listeria monocytogenes

    DEFF Research Database (Denmark)

    Larsen, Marianne Halberg; Sørensen, Martine; Ingmer, Hanne

    to be transmitted to food processing plants from where it can establish and survive for extended periods of time contaminating processed food products. Recently we have identified the response regulator ResD of L. monocytogenes and showed that it is important for growth in laboratory media and for sugar uptake...... in the upstream regulatory region of several genes of L. monocytogenes and the binding of the ResD protein to some of these regulatory regions upstream putative target genes is analysed by electrophoretic mobility shift assays (EMSAs). In conclusion, the response regulator ResD act is important for metabolisme...

  15. Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.

    Science.gov (United States)

    Hamm, Jon; Sullivan, Kristie; Clippinger, Amy J; Strickland, Judy; Bell, Shannon; Bhhatarai, Barun; Blaauboer, Bas; Casey, Warren; Dorman, David; Forsby, Anna; Garcia-Reyero, Natàlia; Gehen, Sean; Graepel, Rabea; Hotchkiss, Jon; Lowit, Anna; Matheson, Joanna; Reaves, Elissa; Scarano, Louis; Sprankle, Catherine; Tunkel, Jay; Wilson, Dan; Xia, Menghang; Zhu, Hao; Allen, David

    2017-06-01

    Acute systemic toxicity testing provides the basis for hazard labeling and risk management of chemicals. A number of international efforts have been directed at identifying non-animal alternatives for in vivo acute systemic toxicity tests. A September 2015 workshop, Alternative Approaches for Identifying Acute Systemic Toxicity: Moving from Research to Regulatory Testing, reviewed the state-of-the-science of non-animal alternatives for this testing and explored ways to facilitate implementation of alternatives. Workshop attendees included representatives from international regulatory agencies, academia, nongovernmental organizations, and industry. Resources identified as necessary for meaningful progress in implementing alternatives included compiling and making available high-quality reference data, training on use and interpretation of in vitro and in silico approaches, and global harmonization of testing requirements. Attendees particularly noted the need to characterize variability in reference data to evaluate new approaches. They also noted the importance of understanding the mechanisms of acute toxicity, which could be facilitated by the development of adverse outcome pathways. Workshop breakout groups explored different approaches to reducing or replacing animal use for acute toxicity testing, with each group crafting a roadmap and strategy to accomplish near-term progress. The workshop steering committee has organized efforts to implement the recommendations of the workshop participants. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Introductory user's manual for the US Nuclear Regulatory Commission Reactor Safety Research Data Bank

    International Nuclear Information System (INIS)

    Scofield, N.R.; Hardy, H.A.; Laats, E.T.

    1983-02-01

    The United States Nuclear Regulatory Commission (NRC) has established the NRC/Division of Accident Evaluation (DAE) Data Bank Program to collect, store, and make available data from the many domestic and foreign water safety research programs. Local direction of the program is provided by E G and G Idaho, Inc., prime contractor for the Department of Energy (DOE) at the Idaho National Engineering Laboratory (INEL). The NRC/DAE Data Bank Program provides a central computer storage mechanism and access software for data that is to be used by code development and assessment groups in meeting the code and correlation needs of the nuclear industry. The administrative portion of the program provides data entry, documentation, training, and advisory services to users and the NRC. The NRC/DAE Data Bank and the capabilities of the data access software are described

  17. Introductory user's manual for the US Nuclear Regulatory Commission Reactor Safety Research Data Bank. Revision 3

    International Nuclear Information System (INIS)

    Hardy, H.A.; Laats, E.T.

    1985-03-01

    The United States Nuclear Regulatory Commission (USNRC) has established the NRC/Division of Accident Evaluation (DAE) Data Bank Program to collect, store, and make available data from the many domestic and foreign water reactor safety research programs. Local direction of the program is provided by EG and G Idaho, Inc., prime contractor for the Department of Energy (DOE) at the Idaho National Engineering Laboratory (INEL). The NRC/DAE Data Bank Program provides a central computer storage mechanism and access software for data to be used by code development and assessment groups in meeting the code correlation needs of the nuclear industry. The administrative portion of the program provides data entry, documentation, training, and advisory services to users and the USNRC. The NRC/DAE Data Bank and the capabilities of the data access software are described in this document

  18. Review and evaluation of the Nuclear Regulatory Commission safety research program for Fiscal Year 1983. Report to the Congress

    International Nuclear Information System (INIS)

    1982-02-01

    Public Law 95-209 includes a requirement that the Advisory Committee on Reactor Safeguards submit an annual report to Congress on the safety research program of the Nuclear Regulatory Commission. This report presents the results of the ACRS review and evaluation of the NRC safety research program for Fiscal Year 1983. The report contains a number of comments and recommendations

  19. A call for action: Improve reporting of research studies to increase the scientific basis for regulatory decision-making

    DEFF Research Database (Denmark)

    Ågerstrand, Marlene; Christiansen, Sofie; Hanberg, Annika

    2018-01-01

    This is a call for action to scientific journals to introduce reporting requirements for toxicity and ecotoxicity studies. Such reporting requirements will support the use of peer-reviewed research studies in regulatory decision-making. Moreover, this could improve the reliability...... and reproducibility of published studies in general and make better use of the resources spent in research....

  20. TuBaFrost 3: regulatory and ethical issues on the exchange of residual tissue for research across Europe

    NARCIS (Netherlands)

    van Veen, E.-B.; Riegman, P. H. J.; Dinjens, W. N. M.; Lam, K. H.; Oomen, M. H. A.; Spatz, A.; Mager, R.; Ratcliffe, C.; Knox, K.; Kerr, D.; van Damme, B.; van de Vijver, M.; van Boven, H.; Morente, M. M.; Alonso, S.; Kerjaschki, D.; Pammer, J.; Lopez-Guerrero, J. A.; Llombart Bosch, A.; Carbone, A.; Gloghini, A.; Teodorovic, I.; Isabelle, M.; Passioukov, A.; Lejeune, S.; Therasse, P.; Oosterhuis, J. W.

    2006-01-01

    The regulatory regimes for research with residual tissue and accompanying data differ widely between countries in the European Union (EU): from specific consent to opt-out or even no consent at all. This could greatly hamper research where the exchange of tissue and accompanying data has become the

  1. PRA research and the development of risk-informed regulation at the U.S. nuclear regulatory commission

    International Nuclear Information System (INIS)

    Siu, Nathan; Collins, Dorothy

    2008-01-01

    Over the years, Probabilistic Risk Assessment (PRA) research activities conducted at the U.S. Nuclear Regulatory Commission (NRC) have played an essential role in support of the agency's move towards risk-informed regulation. These research activities have provided the technical basis for NRC's regulatory activities in key areas; provided PRA methods, tools, and data enabling the agency to meet future challenges; supported the implementation of NRC's 1995 PRA Policy Statement by assessing key sources of risk; and supported the development of necessary technical and human resources supporting NRC's risk-informed activities. PRA research aimed at improving the NRC's understanding of risk can positively affect the agency's regulatory activities, as evidenced by three case studies involving research on fire PRA, Human Reliability Analysis (HRA), and Pressurized Thermal Shock (PTS) PRA. These case studies also show that such research can take a considerable amount of time, and that the incorporation of research results into regulatory practice can take even longer. The need for sustained effort and appropriate lead time is an important consideration in the development of a PRA research program aimed at helping the agency address key sources of risk for current and potential future facilities

  2. Spanish regulatory perspective for the decommissioning of an old civilian nuclear research centre (CIEMAT)

    International Nuclear Information System (INIS)

    Gil, E.; Revilla, J.L.; Rodrigo, F.; Ortiz, J.

    1999-01-01

    The Center for Energy-related, Environmental and Technical Research (CIEMAT) is the main Spanish energy research center. CIEMAT is the heir of the former Nuclear Energy Board (Junta de Energia Nuclear - JEN), which was created in 1951 with a view to promoting the development and use of nuclear energy in Spain. Most of the centres for civilian nuclear research created in the fifties, like the JEN, had among their basic objectives to carry out investigations guided to the industrial development of the nuclear fuel cycle. The majority of them were endowed with experimental facilities that reproduced in a pilot scale the different stages of the full nuclear cycle facilities. The JEN main experimental facilities were: Plants for the treatment of uranium ores and for the concentration process; The manufacturing of fuel elements for research reactors; The JEN-1 thermal neutron experimental reactor, and CORAL fast reactor; The pilot plant for the treatment of irradiated fuel (M-1); The metallurgical hot cells for research relating to irradiated fuel; and Plants for the treatment and storage of liquid radioactive wastes. It should be pointed out that most of these installations were designed, built, operated, and even definitively shut down, prior a regulatory system as currently conceived is in force. The Science Act was passed in 1986, transforming the JEN into CIEMAT, and assigning to the latter a series of new functions, while making it the direct heir of the assets and strategic functions of its predecessor. The CIEMAT continued the process of 'denuclearization' of the installations inherited from the JEN, and used certain of them for the performance of research projects oriented towards the development of decontamination and dismantling techniques. (author)

  3. PHITS code improvements by Regulatory Standard and Research Department Secretariat of Nuclear Regulation Authority

    International Nuclear Information System (INIS)

    Goko, Shinji

    2017-01-01

    As for the safety analysis to be carried out when a nuclear power company applies for installation permission of facility or equipment, business license, design approval etc., the Regulatory Standard and Research Department Secretariat of Nuclear Regulation Authority continuously conducts safety research for the introduction of various technologies and their improvement in order to evaluate the adequacy of this safety analysis. In the field of the shielding analysis of nuclear fuel transportation materials, this group improved the code to make PHITS applicable to this field, and has been promoting the improvement as a tool used for regulations since FY2013. This paper introduced the history and progress of this safety research. PHITS 2.88, which is the latest version as of November 2016, was equipped with the automatic generation function of variance reduction parameters [T-WWG] etc., and developed as the tool equipped with many effective functions in practical application to nuclear power regulations. In addition, this group conducted the verification analysis against nuclear fuel packages, which showed a good agreement with the analysis by MCNP, which is extensively used worldwide and abundant in actual results. It also shows a relatively good agreement with the measured values, when considering differences in analysis and measurement. (A.O.)

  4. Regulatory Guidance for Lightning Protection in Nuclear Power Plants

    International Nuclear Information System (INIS)

    Kisner, Roger A.; Wilgen, John B.; Ewing, Paul D.; Korsah, Kofi; Antonescu, Christina E.

    2006-01-01

    Oak Ridge National Laboratory (ORNL) was engaged by the U.S. Nuclear Regulatory Commission (NRC) Office of Nuclear Regulatory Research (RES) to develop the technical basis for regulatory guidance to address design and implementation practices for lightning protection systems in nuclear power plants (NPPs). Lightning protection is becoming increasingly important with the advent of digital and low-voltage analog systems in NPPs. These systems have the potential to be more vulnerable than older analog systems to the resulting power surges and electromagnetic interference (EMI) when lightning strikes facilities or power lines. This paper discusses the technical basis for guidance to licensees and applicants covered in Regulatory Guide (RG) 1.204, Guidelines for Lightning Protection of Nuclear Power Plants, issued August 2005. RG 1.204 describes guidance for practices that are acceptable to the NRC staff for protecting nuclear power structures and systems from direct lightning strikes and the resulting secondary effects.

  5. Teine Res Musica ilmunud / Jaan Ross

    Index Scriptorium Estoniae

    Ross, Jaan, 1957-

    2010-01-01

    Artiklikogumikust: Res musica [2] : Eesti Muusikateaduse Seltsi ja Eesti Muusika- ja Teatriakadeemia muusikateaduse osakonna aastaraamat / peatoimetaja Urve Lippus. Tallinn : Eesti Muusika- ja Teatriakadeemia, 2010

  6. Research Project Control System (RPCS); research results utilization data as of 06/30/81. Status summary report

    International Nuclear Information System (INIS)

    1981-09-01

    The report on 'Research Results Utilization' provides status and control information concerning the utilization of research results in the regulatory policies and practices of the NRC. Research Information Letters (RILs) are prepared by RES to transmit research results to NRC user offices upon completion of a substantial, coherent and reasonably complete body of experimental and/or analytical research work. Section 3.0 of this report lists the RILs issued to date, together with an identification of the research program manager and the research program element which generated the RIL. The potential applicability of each RIL to the regulatory process is also identified, and comments from the cognizant RES and user office staff are summarized which relate to the expected impact of the reported RILs on the regulatory process

  7. Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor.

    Science.gov (United States)

    Surya, Sanjna L; Long, Marcus J C; Urul, Daniel A; Zhao, Yi; Mercer, Emily J; EIsaid, Islam M; Evans, Todd; Aye, Yimon

    2018-02-08

    Small heat shock protein (sHSP)-B7 (HSPB7) is a muscle-specific member of the non-ATP-dependent sHSPs. The precise role of HSPB7 is enigmatic. Here, we disclose that zebrafish Hspb7 is a kinetically privileged sensor that is able to react rapidly with native reactive electrophilic species (RES), when only substoichiometric amounts of RES are available in proximity to Hspb7 expressed in living cells. Among the two Hspb7-cysteines, this RES sensing is fulfilled by a single cysteine (C117). Purification and characterizations in vitro reveal that the rate for RES adduction is among the most efficient reported for protein-cysteines with native carbonyl-based RES. Covalent-ligand binding is accompanied by structural changes (increase in β-sheet-content), based on circular dichroism analysis. Among the two cysteines, only C117 is conserved across vertebrates; we show that the human ortholog is also capable of RES sensing in cells. Furthermore, a cancer-relevant missense mutation reduces this RES-sensing property. This evolutionarily conserved cysteine-biosensor may play a redox-regulatory role in cardioprotection.

  8. Regulatory Approach to Safety of Long Time Operating Research Reactors in Russia

    International Nuclear Information System (INIS)

    Sapozhnikov, Alexander

    2013-01-01

    In the Russian Federation more than 60% of operating Nuclear Research Facilities (NRFs) are of age over 30 years old or their usage exceeds originally conceived continuous operation. In this regard, important areas of regulatory body activity are: 1) a systematic assessment of the actual state of structures, systems and components (SSCs) important to safety, 2) control of implementation of organizational and technical measures to mitigate ageing impact on the basis of programmes to manage reliability (service life) of SSCs, and 3) issues of facility modification/reconstruction in line with up-to-day safety requirements. The practice of licensing NRFs with long operating times shows that the national regulations are generally in compliance with IAEA recommendations for ageing management of research reactors. In operating organizations, the ageing management is being effectively provided as a part of the integrated management system for NRFs, including the monitoring of the reliability of SSCs, a methodology to detect their ageing, reporting and investigation of events, analysis of their root causes, and measures to prevent and mitigate ageing effects to safety. The report outlines a good practice of safety regulation of NRFs with long operating times and based on lessons learned from experience, including challenges for future improvement of ageing management

  9. Regulatory Approach to Safety of Long Time Operating Research Reactors in Russia

    Energy Technology Data Exchange (ETDEWEB)

    Sapozhnikov, Alexander [Industrial and Nuclear Supervision Service, Moscow (Russian Federation)

    2013-07-01

    In the Russian Federation more than 60% of operating Nuclear Research Facilities (NRFs) are of age over 30 years old or their usage exceeds originally conceived continuous operation. In this regard, important areas of regulatory body activity are: 1) a systematic assessment of the actual state of structures, systems and components (SSCs) important to safety, 2) control of implementation of organizational and technical measures to mitigate ageing impact on the basis of programmes to manage reliability (service life) of SSCs, and 3) issues of facility modification/reconstruction in line with up-to-day safety requirements. The practice of licensing NRFs with long operating times shows that the national regulations are generally in compliance with IAEA recommendations for ageing management of research reactors. In operating organizations, the ageing management is being effectively provided as a part of the integrated management system for NRFs, including the monitoring of the reliability of SSCs, a methodology to detect their ageing, reporting and investigation of events, analysis of their root causes, and measures to prevent and mitigate ageing effects to safety. The report outlines a good practice of safety regulation of NRFs with long operating times and based on lessons learned from experience, including challenges for future improvement of ageing management.

  10. Development of Regulatory Technical Requirements for the Advanced Integral Type Research Reactor

    International Nuclear Information System (INIS)

    Jo, Jong Chull; Yune, Young Gill; Kim, Woong Sik; Kim, Hho Jung

    2004-01-01

    This paper presents the current status of the study on the development of regulatory technical requirements for the licensing review of an advanced integral type research reactor of which the license application is expected in a few years. According to the Atomic Energy Act of Korea, both research and education reactors are subject to the technical requirements for power reactors in the licensing review. But, some of the requirements may not be applicable or insufficient for the licensing reviews of reactors with unique design features. Thus it is necessary to identify which review topics or areas can not be addressed by the existing requirements and to develop the required ones newly or supplement appropriately. Through the study performed so far, it has been identified that the following requirements need to be developed newly for the licensing review of SMART-P: the use of proven technology, the interfacial facility, the non-safety systems, and the metallic fuels. The approach and basis for the development of each of the requirements are discussed. (authors)

  11. A deviation from standard design? Clinical trials, research ethics committees, and the regulatory co-construction of organizational deviance.

    Science.gov (United States)

    Hedgecoe, Adam

    2014-02-01

    Focusing on the high-profile drug disaster at London's Northwick Park Hospital in 2006, this article explores how such an event can be seen as an example of organizational deviance co-constructed between the company running the research and the research ethics committee which approved the trial. This deviance was the result of the normalization of a specific dosing practice in the broader regulatory field, allowing the researchers and regulators to take a risky dosing strategy for granted as best practice. Drawing on the work of Diane Vaughan, this article uses interview data with researchers and members of the research ethics committee concerned as well as documentary material, to show how work group cultures between regulators and those they are intended to oversee are maintained, and how the culturally embedded assumptions of such work groups can result in organizational and regulatory deviance.

  12. Frontières sociales, frontières culturelles, frontières techniques

    Directory of Open Access Journals (Sweden)

    2010-12-01

    Full Text Available Les sociétés démocratiques modernes ont basé leur unité sur l'égalité des chances et sur la mobilité sociale. Or, ce modèle d'intégration est fortement mis à l'épreuve aujourd'hui. Des discriminations structurelles viennent contredire le principe l'égalité de traitement. Des barrières difficilement franchissables, quel que soit le niveau, viennent contrecarrer la possibilité de promotion sociale. Un double phénomène est ainsi observable. D'une part, la société se fractionne en des espaces soc...

  13. A call for action: Improve reporting of research studies to increase the scientific basis for regulatory decision-making

    DEFF Research Database (Denmark)

    Ågerstrand, Marlene; Christiansen, Sofie; Hanberg, Annika

    2018-01-01

    This is a call for action to scientific journals to introduce reporting requirements for toxicity and ecotoxicity studies. Such reporting requirements will support the use of peer-reviewed research studies in regulatory decision-making. Moreover, this could improve the reliability and reproducibi...

  14. Res Publica soolo rikkus tavasid / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    Riigikogu aseesimeheks valiti Res Publica liige Taavi Veskimägi, nüüd on Riigikogu juhatuses kaks ühe partei liiget. Riigikogu aseesimeheks tagasi valitud Toomas Vareki hinnangul näitab see samm nii Res Publica kogenematust kui ka Eesti poliitilise kultuuri kehva taset

  15. Res Publica otsib kandepinda / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2004-01-01

    Res Publica peasekretäri Ott Lumi sõnul on erakond teinud tõsised järeldused Euroopa Parlamendi valimiste tulemusest. Res Publica parlamendifraktsiooni väljasõidul pidas kriitilise kõne erakonna esimees Juhan Parts

  16. U.S. Department of Energy & Nuclear Regulatory Commission Advanced Fuel Cycle Research & Development Seminar Series FY 2007 & 2008

    Energy Technology Data Exchange (ETDEWEB)

    Grandy, Christopher [Argonne National Lab. (ANL), Argonne, IL (United States)

    2008-08-01

    In fiscal year 2007, the Advanced Burner Reactor project initiated an educational seminar series for the Department of Energy (DOE) and Nuclear Regulatory Commission (NRC) personnel on various aspects of fast reactor fuel cycle closure technologies. This important work was initiated to inform DOE and NRC personnel on initial details of sodium-cooled fast reactor, separations, waste form, and safeguard technologies being considered for the Advanced Fuel Cycle Research and Development program, and to learn the important lesson from the licensing process for the Clinch River Breeder Reactor Plant that educating the NRC staff early in the regulatory process is very important and critical to a project success.

  17. Regulatory Research of the PWR Severe Accident. Information Needs and Instrumentation for Hydrogen Control and Management

    International Nuclear Information System (INIS)

    Park, Gun Chul; Suh, Kune Y.; Lee, Jin Yong; Lee, Seung Dong

    2001-03-01

    The current research is concerned with generation of basic engineering data needed in the process of developing hydrogen control guidelines as part of accident management strategies for domestic nuclear power plants and formulating pertinent regulatory requirements. Major focus is placed on identification of information needs and instrumentation methods for hydrogen control and management in the primary system and in the containment, development of decision-making trees for hydrogen management and their quantification, the instrument availability under severe accident conditions, critical review of relevant hydrogen generation model and phenomena In relation to hydrogen behavior, we analyzed the severe accident related hydrogen generation in the UCN 3·4 PWR with modified hydrogen generation model. On the basis of the hydrogen mixing experiment and related GASFLOW calculation, the necessity of 3-dimensional analysis of the hydrogen mixing was investigated. We examined the hydrogen control models related to the PAR(Passive Autocatalytic Recombiner) and performed MAAP4 calculation in relation to the decision tree to estimate the capability and the role of the PAR during a severe accident

  18. Regulatory Research of the PWR Severe Accident. Information Needs and Instrumentation for Hydrogen Control and Management

    Energy Technology Data Exchange (ETDEWEB)

    Park, Gun Chul; Suh, Kune Y.; Lee, Jin Yong; Lee, Seung Dong [Seoul Nat' l Univ., Seoul (Korea, Republic of)

    2001-03-15

    The current research is concerned with generation of basic engineering data needed in the process of developing hydrogen control guidelines as part of accident management strategies for domestic nuclear power plants and formulating pertinent regulatory requirements. Major focus is placed on identification of information needs and instrumentation methods for hydrogen control and management in the primary system and in the containment, development of decision-making trees for hydrogen management and their quantification, the instrument availability under severe accident conditions, critical review of relevant hydrogen generation model and phenomena In relation to hydrogen behavior, we analyzed the severe accident related hydrogen generation in the UCN 3{center_dot}4 PWR with modified hydrogen generation model. On the basis of the hydrogen mixing experiment and related GASFLOW calculation, the necessity of 3-dimensional analysis of the hydrogen mixing was investigated. We examined the hydrogen control models related to the PAR(Passive Autocatalytic Recombiner) and performed MAAP4 calculation in relation to the decision tree to estimate the capability and the role of the PAR during a severe accident.

  19. U.S. regulatory initiatives related to nuclear research and development

    International Nuclear Information System (INIS)

    Carr, K.M.

    1987-01-01

    U.S. Nuclear Regulatory Commission is working to improve its 'early warning system' in order to recognize trends and identify potential safety problems whether the source of the problems relates to a reactor safety system or to a utility management or organizational issue. The Commission has approved the use of performance indicators to provide a more effective means for top NRC management and the Commission to recognize changes in the safety performance of operating reactors. Research also has a leading role in assuring the safety of the evolving nuclear technology. The primary role of NRC's program is to provide a sound technical basis for decisions on the resolution of safety issues for the current generation of plants and safety issues that may arise for future designs. Topical areas essential to resolve the remaining safety issues or uncertainties related to LWR operation are human factors and accident management, life extension and plant aging, studies on containment integrity, severe accident risk analysis and uncertainty resolution, reliability engineering and the analysis of thermal-hydraulic transients. (Nogami, K.)

  20. Isamaaliidu ühinemisjutt ajas Res Publica keema / Toomas Sildam

    Index Scriptorium Estoniae

    Sildam, Toomas, 1961-

    2005-01-01

    Ilmunud ka: Postimees : na russkom jazõke 14. nov., lk 3. Isamaaliidu esimehe Tõnis Lukase ettepanekut Isamaaliidu ja Res Publica ühinemiseks pooldavad ka Res Publica eestseisuse liikmed Juhan Parts ja Tõnis Palts, kuid Res Publica esimehe Taavi Veskimäe kinnitusel läheb Res Publica 2007. aasta parlamendivalimistele vastu iseseisvalt. Lisa: Isamaaliit ja Res Publica

  1. Reactors licensing: proposal of an integrated quality and environment regulatory structure for nuclear research reactors in Brazil

    International Nuclear Information System (INIS)

    Serra, Reynaldo Cavalcanti

    2014-01-01

    A new integrated regulatory structure based on quality and integrated issues has been proposed to be implemented on the licensing process of nuclear research reactors in Brazil. The study starts with a literature review about the licensing process in several countries, all of them members of the International Atomic Energy Agency. After this phase it is performed a comparative study with the Brazilian licensing process to identify good practices (positive aspects), the gaps on it and to propose an approach of an integrated quality and environmental management system, in order to contribute with a new licensing process scheme in Brazil. The literature review considered the following research nuclear reactors: Jules-Horowitz and OSIRIS (France), Hanaro (Korea), Maples 1 and 2 (Canada), OPAL (Australia), Pallas (Holand), ETRR-2 (Egypt) and IEA-R1 (Brazil). The current nuclear research reactors licensing process in Brazil is conducted by two regulatory bodies: the Brazilian National Nuclear Energy Commission (CNEN) and the Brazilian Institute of Environment and Renewable Natural Resources (IBAMA). CNEN is responsible by nuclear issues, while IBAMA by environmental one. To support the study it was applied a questionnaire and interviews based on the current regulatory structure to four nuclear research reactors in Brazil. Nowadays, the nuclear research reactor’s licensing process, in Brazil, has six phases and the environmental licensing process has three phases. A correlation study among these phases leads to a proposal of a new quality and environmental integrated licensing structure with four harmonized phases, hence reducing potential delays in this process. (author)

  2. Problematizing Digital Research Evaluation using DOIs in Practice-Based Arts, Humanities and Social Science Research [v1; ref status: indexed, http://f1000r.es/5dy

    Directory of Open Access Journals (Sweden)

    Muriel Swijghuisen Reigersberg

    2015-07-01

    Full Text Available This paper explores emerging practices in research data management in the arts, humanities and social sciences (AHSS. It will do so vis-à-vis current citation conventions and impact measurement for research in AHSS. Case study findings on research data inventoried at Goldsmiths’, University of London will be presented. Goldsmiths is a UK research-intensive higher education institution which specialises in arts, humanities and social science research. The paper’s aim is to raise awareness of the subject-specific needs of AHSS scholars to help inform the design of future digital tools for impact analysis in AHSS. Firstly, I shall explore the definition of research data and how it is currently understood by AHSS researchers. I will show why many researchers choose not to engage with digital dissemination techniques and ORCID. This discussion must necessarily include the idea that practice-based and applied AHSS research are processes which are not easily captured in numerical ‘sets’ and cannot be labelled electronically without giving careful consideration to what a group or data item ‘represents’ as part of the academic enquiry, and therefore how it should be cited and analysed as part of any impact assessment. Then, the paper will explore: the role of the monograph and arts catalogue in AHSS scholarship; how citation practices and digital impact measurement in AHSS currently operate in relation to authorship and how digital identifiers may hypothetically impact on metrics, intellectual property (IP, copyright and research integrity issues in AHSS. I will also show that, if we are to be truly interdisciplinary, as research funders and strategic thinkers say we should, it is necessary to revise the way we think about digital research dissemination. This will involve breaking down the boundaries between AHSS and other types of research.

  3. Recent NRC research activities addressing valve and pump issues

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, D.L.

    1996-12-01

    The mission of the U.S. Nuclear Regulatory Commission (NRC) is to ensure the safe design, construction, and operation of commercial nuclear power plants and other facilities in the U.S.A. One of the main roles that the Office of Nuclear Regulatory Research (RES) plays in achieving the NRC mission is to plan, recommend, and implement research programs that address safety and technical issues deemed important by the NRC. The results of the research activities provide the bases for developing NRC positions or decisions on these issues. Also, RES performs confirmatory research for developing the basis to evaluate industry responses and positions on various regulatory requirements. This presentation summarizes some recent RES supported research activities that have addressed safety and technical issues related to valves and pumps. These activities include the efforts on determining valve and motor-operator responses under dynamic loads and pressure locking events, evaluation of monitoring equipment, and methods for detecting and trending aging of check valves and pumps. The role that RES is expected to play in future years to fulfill the NRC mission is also discussed.

  4. Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN

    Directory of Open Access Journals (Sweden)

    Sanz Nuria

    2009-10-01

    Full Text Available Abstract Background Thorough knowledge of the regulatory requirements is a challenging prerequisite for conducting multinational clinical studies in Europe given their complexity and heterogeneity in regulation and perception across the EU member states. Methods In order to summarise the current situation in relation to the wide spectrum of clinical research, the European Clinical Research Infrastructures Network (ECRIN developed a multinational survey in ten European countries. However a lack of common classification framework for major categories of clinical research was identified, and therefore reaching an agreement on a common classification was the initial step in the development of the survey. Results The ECRIN transnational working group on regulation, composed of experts in the field of clinical research from ten European countries, defined seven major categories of clinical research that seem relevant from both the regulatory and the scientific points of view, and correspond to congruent definitions in all countries: clinical trials on medicinal products; clinical trials on medical devices; other therapeutic trials (including surgery trials, transplantation trials, transfusion trials, trials with cell therapy, etc.; diagnostic studies; clinical research on nutrition; other interventional clinical research (including trials in complementary and alternative medicine, trials with collection of blood or tissue samples, physiology studies, etc.; and epidemiology studies. Our classification was essential to develop a survey focused on protocol submission to ethics committees and competent authorities, procedures for amendments, requirements for sponsor and insurance, and adverse event reporting following five main phases: drafting, consensus, data collection, validation, and finalising. Conclusion The list of clinical research categories as used for the survey could serve as a contribution to the, much needed, task of harmonisation and

  5. Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN)

    LENUS (Irish Health Repository)

    Kubiak, Christine

    2009-10-16

    Abstract Background Thorough knowledge of the regulatory requirements is a challenging prerequisite for conducting multinational clinical studies in Europe given their complexity and heterogeneity in regulation and perception across the EU member states. Methods In order to summarise the current situation in relation to the wide spectrum of clinical research, the European Clinical Research Infrastructures Network (ECRIN) developed a multinational survey in ten European countries. However a lack of common classification framework for major categories of clinical research was identified, and therefore reaching an agreement on a common classification was the initial step in the development of the survey. Results The ECRIN transnational working group on regulation, composed of experts in the field of clinical research from ten European countries, defined seven major categories of clinical research that seem relevant from both the regulatory and the scientific points of view, and correspond to congruent definitions in all countries: clinical trials on medicinal products; clinical trials on medical devices; other therapeutic trials (including surgery trials, transplantation trials, transfusion trials, trials with cell therapy, etc.); diagnostic studies; clinical research on nutrition; other interventional clinical research (including trials in complementary and alternative medicine, trials with collection of blood or tissue samples, physiology studies, etc.); and epidemiology studies. Our classification was essential to develop a survey focused on protocol submission to ethics committees and competent authorities, procedures for amendments, requirements for sponsor and insurance, and adverse event reporting following five main phases: drafting, consensus, data collection, validation, and finalising. Conclusion The list of clinical research categories as used for the survey could serve as a contribution to the, much needed, task of harmonisation and simplification of the

  6. CCR 20th Anniversary Commentary: From Regulatory T Cells to Checkpoint Monoclonal Antibodies--Immuno-oncology Advances Clinical Cancer Research.

    Science.gov (United States)

    Wolf, Dominik; Wolf, Anna Maria

    2015-06-15

    Immune escape is a hallmark of cancer development and metastasis. Regulatory T cells (Treg) are potent inhibitors of cancer immune surveillance but also prevent inflammation-driven tumorigenesis. The study by Wolf and colleagues, which was published in the February 2003 issue of Clinical Cancer Research, showed the expansion of Treg in solid cancer patients, providing a deeper understanding of cancer immune escape mechanisms that later set the stage for the development of scientific breakthroughs in cancer immunotherapy. ©2015 American Association for Cancer Research.

  7. Implementation of Good Laboratory Practices (GLP) in basic scientific research: Translating the concept beyond regulatory compliance.

    Science.gov (United States)

    Jena, G B; Chavan, Sapana

    2017-10-01

    The principles of Good Laboratory Practices (GLPs) are mainly intended for the laboratories performing studies for regulatory compliances. However, today GLP can be applied to broad disciplines of science to cater to the needs of the experimental objectives, generation of quality data and assay reproducibility. Considering its significance, it can now be applied in academics; industries as well as government set ups throughout the world. GLP is the best way to promote the reliability, reproducibility of the test data and hence facilitates the international acceptability. Now it is high time to translate and implement the concept of GLP beyond regulatory studies. Thus, it can pave the way for better understanding of scientific problems and help to maintain a good human and environmental health. Through this review, we have made an attempt to explore the uses of GLP principles in different fields of science and its acceptability as well as looking for its future perspectives. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Nuclear Energy Research Initiative. Risk Informed Assessment of Regulatory and Design Requirements for Future Nuclear Power Plants. Annual Report

    International Nuclear Information System (INIS)

    Ritterbusch, S.E.

    2000-01-01

    The overall goal of this research project is to support innovation in new nuclear power plant designs. This project is examining the implications, for future reactors and future safety regulation, of utilizing a new risk-informed regulatory system as a replacement for the current system. This innovation will be made possible through development of a scientific, highly risk-informed approach for the design and regulation of nuclear power plants. This approach will include the development and.lor confirmation of corresponding regulatory requirements and industry standards. The major impediment to long term competitiveness of new nuclear plants in the U.S. is the capital cost component--which may need to be reduced on the order of 35% to 40% for Advanced Light Water Reactors (ALWRs) such as System 80+ and Advanced Boiling Water Reactor (ABWR). The required cost reduction for an ALWR such as AP600 or AP1000 would be expected to be less. Such reductions in capital cost will require a fundamental reevaluation of the industry standards and regulatory bases under which nuclear plants are designed and licensed. Fortunately, there is now an increasing awareness that many of the existing regulatory requirements and industry standards are not significantly contributing to safety and reliability and, therefore, are unnecessarily adding to nuclear plant costs. Not only does this degrade the economic competitiveness of nuclear energy, it results in unnecessary costs to the American electricity consumer. While addressing these concerns, this research project will be coordinated with current efforts of industry and NRC to develop risk-informed, performance-based regulations that affect the operation of the existing nuclear plants; however, this project will go farther by focusing on the design of new plants

  9. Nuclear Energy Research Initiative. Risk Informed Assessment of Regulatory and Design Requirements for Future Nuclear Power Plants. Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Ritterbusch, S.E.

    2000-08-01

    The overall goal of this research project is to support innovation in new nuclear power plant designs. This project is examining the implications, for future reactors and future safety regulation, of utilizing a new risk-informed regulatory system as a replacement for the current system. This innovation will be made possible through development of a scientific, highly risk-informed approach for the design and regulation of nuclear power plants. This approach will include the development and.lor confirmation of corresponding regulatory requirements and industry standards. The major impediment to long term competitiveness of new nuclear plants in the U.S. is the capital cost component--which may need to be reduced on the order of 35% to 40% for Advanced Light Water Reactors (ALWRs) such as System 80+ and Advanced Boiling Water Reactor (ABWR). The required cost reduction for an ALWR such as AP600 or AP1000 would be expected to be less. Such reductions in capital cost will require a fundamental reevaluation of the industry standards and regulatory bases under which nuclear plants are designed and licensed. Fortunately, there is now an increasing awareness that many of the existing regulatory requirements and industry standards are not significantly contributing to safety and reliability and, therefore, are unnecessarily adding to nuclear plant costs. Not only does this degrade the economic competitiveness of nuclear energy, it results in unnecessary costs to the American electricity consumer. While addressing these concerns, this research project will be coordinated with current efforts of industry and NRC to develop risk-informed, performance-based regulations that affect the operation of the existing nuclear plants; however, this project will go farther by focusing on the design of new plants.

  10. Renewables portfolio, individual preferences and social values towards RES technologies

    International Nuclear Information System (INIS)

    Kontogianni, Areti; Tourkolias, Christos; Skourtos, Michalis

    2013-01-01

    The massive deployment of renewable energy sources represents a high priority for Greece in order to comply with the Directive 2009/28/EC on the promotion of the use of energy from renewable sources by 2020. In this perspective, Aegean islands especially Lesvos, are endowed with a considerable potential of a portfolio of renewables, a fact that the entrepreneurial interest has already been targeted. However, regulatory attempts for a massive penetration of renewables do not take seriously into account preferences and risk perceptions of local communities where the proposed projects are to be installed. The aim of this study is to investigate individual preferences and social values towards specific technologies of renewables in Lesvos island. We apply an open-ended contingent valuation survey in order to analyze factors shaping public attitudes towards a portfolio of renewable technologies and estimate the economic welfare (Willingness To Pay) of the preferred technologies. We argue that such information is relevant for energy policy design and the establishment of effective measures for the promotion of renewable energy sources. - Highlights: ► We investigate individual preferences and attitudes towards a portfolio of RES technologies. ► We elicit public acceptance for investing in specific RES technologies. ► We analyze factors shaping public preferences of the preferred technologies. ► We estimate the economic welfare of the preferred technologies

  11. The role of research-article writing motivation and self-regulatory strategies in explaining research-article abstract writing ability.

    Science.gov (United States)

    Lin, Ming-Chia; Cheng, Yuh-Show; Lin, Sieh-Hwa; Hsieh, Pei-Jung

    2015-04-01

    The purpose of the study was to investigate the effects of research-article writing motivation and use of self-regulatory writing strategies in explaining second language (L2) research-article abstract writing ability, alongside the L2 literacy effect. Four measures were administered: a L2 literacy test, a research abstract performance assessment, and inventories of writing motivation and strategy. Participants were L2 graduate students in Taiwan (N=185; M age=25.8 yr., SD=4.5, range=22-53). Results of structural equation modeling showed a direct effect of motivation on research-article writing ability, but no direct effect of strategy or indirect effect of motivation via strategy on research-article writing ability, with L2 literacy controlled. The findings suggest research-article writing instruction should address writing motivation, besides L2 literacy.

  12. Review and evaluation of the Nuclear Regulatory Commission Safety Research Program for Fiscal Years 1984 and 1985

    International Nuclear Information System (INIS)

    1983-02-01

    This is the sixth report by the Advisory Committee on Reactor Safeguards (ACRS) that has been prepared in response to the Congressional requirement for an annual report on the Nuclear Regulatory Commission (NRC) Reactor Safety Research Program. Part I is a compilation of our general comments and recommendations regarding the NRC Safety Research Program, and includes budget recommendations and an identification of matters of special importance that deserve increased emphasis. It is intended to serve as an Executive Summary. Part II is divided into ten chapters, each of which represents a Decision Unit of the NRC research program. In each chapter, specific comments are included on the research involved in the Decision Unit, an assessment of priorities, and recommendations regarding new directions and levels of funding

  13. The U.S. Nuclear Regulatory Commission Thermal-Hydraulic Research Program: Maintaining expertise in a changing environment

    International Nuclear Information System (INIS)

    Sheron, B.W.; Shotkin, L.M.; Baratta, A.J.

    1993-01-01

    Throughout the 1970s and early 1980s, the U.S. Nuclear Regulatory Commission's (NRC's) thermal-hydraulic research program enjoyed ample funding, sponsored extensive experimental and analytical development programs, and attracted worldwide expertise. With the completion of the major experimental programs and with the promulgation of the revised emergency core-cooling system rule, both the funding and prominence of thermal-hydraulic research at the NRC have declined in recent years. This has led justifiably to the concern by some that the program may no longer have the minimal elements needed to maintain both expertise and world-class status. The purpose of this article is to describe the NRC's current thermal-hydraulic research program and to show how this program ensures maintenance of a viable, robust research effort and retention of needed expertise and international leadership

  14. Arrangement between the US Nuclear Regulatory Commission (USNRC) and the Belgian Government for Exchange of Technical Information in Regulatory Matters and in Cooperation in Safety Research and in Standards Development

    International Nuclear Information System (INIS)

    1978-01-01

    This Arrangement was concluded on 6 June 1978 between the United States Nuclear Regulatory Commission and the Belgian Government for exchange of technical information in regulatory matters and in co-operation in safety research and in standards development. Both Parties agree to exchange, as available, technical information related to the regulation of safety and the environmental impact of designated nuclear energy facilities and to safety research of designated types of nuclear facilities. As regards co-operation in safety research, the execution of joint programmes and projects under which activities are divided between the two Parties will be agreed on a case by case basis. The Parties further agree to co-operate in the development of regulatory standards applicable to the designated nuclear facilities. The Arrangement is valid for 5 years and may be extended. (NEA) [fr

  15. How Has CDER Prepared for the Nano Revolution? A Review of Risk Assessment, Regulatory Research, and Guidance Activities.

    Science.gov (United States)

    Tyner, Katherine M; Zheng, Nan; Choi, Stephanie; Xu, Xiaoming; Zou, Peng; Jiang, Wenlei; Guo, Changning; Cruz, Celia N

    2017-07-01

    The Nanotechnology Risk Assessment Working Group in the Center for Drug Evaluation and Research (CDER) within the United States Food and Drug Administration (FDA) was established to assess the potential impact of nanotechnology on drug products. One of the working group's major initiatives has been to conduct a comprehensive risk management exercise regarding the potential impact of nanomaterial pharmaceutical ingredients and excipients on drug product quality, safety, and efficacy. This exercise concluded that current review practices and regulatory guidance are capable of detecting and managing the potential risks to quality, safety, and efficacy when a drug product incorporates a nanomaterial. However, three risk management areas were identified for continued focus during the review of drug products containing nanomaterials: (1) the understanding of how to perform the characterization of nanomaterial properties and the analytical methods used for this characterization, (2) the adequacy of in vitro tests to evaluate drug product performance for drug products containing nanomaterials, and (3) the understanding of properties arising from nanomaterials that may result in different toxicity and biodistribution profiles for drug products containing nanomaterials. CDER continues to actively track the incorporation of nanomaterials in drug products and the methodologies used to characterize them, in order to continuously improve the readiness of our science- and risk-based review approaches. In parallel to the risk management exercise, CDER has also been supporting regulatory research in the area of nanotechnology, specifically focused on characterization, safety, and equivalence (between reference and new product) considerations. This article provides a comprehensive summary of regulatory and research efforts supported by CDER in the area of drug products containing nanomaterials and other activities supporting the development of this emerging technology.

  16. Uranium recovery research sponsored by the Nuclear Regulatory Commission at Pacific Northwest Laboratory. Annual progress report, May 1982-May 1983

    International Nuclear Information System (INIS)

    Foley, M.G.; Opitz, B.E.; Deutsch, W.J.

    1983-06-01

    Pacific Northwest Laboratory (PNL) is currently conducting research for the US Nuclear Regulatory Commission (NRC) on uranium recovery process wastes for both active and inactive operations. NRC-sponsored uranium recovery research at PNL is focused on NRC regulatory responsibilities for uranium-recovery operations: license active milling and in situ extraction operations; concur on the acceptability of DOE remedial-action plans for inactive sites; and license DOE to maintain inactive sites following remedial actions. PNL's program consists of four coordinated projects comprised of a program management task and nine research tasks that address the critical technical and safety issues for uranium recovery. Specifically, the projects endeavor to find and evaluate methods to: prevent erosion of tailings piles and prevent radon release from tailings piles; evaluate the effectiveness of interim stabilization techniques to prevent wind erosion and transport of dry tailings from active piles; estimate the dewatering and consolidation behavior of slurried tailings to promote early cover placement; design a cover-protection system to prevent erosion of the cover by expected environmental stresses; reduce seepage into ground water and prevent ground-water degradation; control solution movement and reaction with ground water in in-situ extraction operations; evaluate natural and induced restoration of ground water in in-situ extraction operations; and monitor releases to the environment from uranium recovery facilities

  17. Uranium recovery research sponsored by the Nuclear Regulatory Commission at Pacific Northwest Laboratory. Annual progress report, May 1982-May 1983

    Energy Technology Data Exchange (ETDEWEB)

    Foley, M.G.; Opitz, B.E.; Deutsch, W.J.; Peterson, S.R.; Gee, G.W.; Serne, R.J.; Hartley, J.N.; Thomas, V.W.; Kalkwarf, D.R.; Walters, W.H.

    1983-06-01

    Pacific Northwest Laboratory (PNL) is currently conducting research for the US Nuclear Regulatory Commission (NRC) on uranium recovery process wastes for both active and inactive operations. NRC-sponsored uranium recovery research at PNL is focused on NRC regulatory responsibilities for uranium-recovery operations: license active milling and in situ extraction operations; concur on the acceptability of DOE remedial-action plans for inactive sites; and license DOE to maintain inactive sites following remedial actions. PNL's program consists of four coordinated projects comprised of a program management task and nine research tasks that address the critical technical and safety issues for uranium recovery. Specifically, the projects endeavor to find and evaluate methods to: prevent erosion of tailings piles and prevent radon release from tailings piles; evaluate the effectiveness of interim stabilization techniques to prevent wind erosion and transport of dry tailings from active piles; estimate the dewatering and consolidation behavior of slurried tailings to promote early cover placement; design a cover-protection system to prevent erosion of the cover by expected environmental stresses; reduce seepage into ground water and prevent ground-water degradation; control solution movement and reaction with ground water in in-situ extraction operations; evaluate natural and induced restoration of ground water in in-situ extraction operations; and monitor releases to the environment from uranium recovery facilities.

  18. Hierarchical architecture of ReS_2/rGO composites with enhanced electrochemical properties for lithium-ion batteries

    International Nuclear Information System (INIS)

    Qi, Fei; Chen, Yuanfu; Zheng, Binjie; He, Jiarui; Li, Qian; Wang, Xinqiang; Lin, Jie; Zhou, Jinhao; Yu, Bo; Li, Pingjian; Zhang, Wanli

    2017-01-01

    Highlights: • The ReS_2/rGO composites have been synthesized by a facile one-pot method. • The ReS_2/rGO composites exhibit hierarchical architecture. • The ReS_2/rGO composites deliver better electrochemical performances than ReS_2. • The enhanced performance is due to porous and conductive structure of ReS_2/rGO. - Abstract: Rhenium disulfide (ReS_2), a two-dimensional (2D) semiconductor, has attracted more and more attention due to its unique anisotropic electronic, optical, mechanical properties. However, the facile synthesis and electrochemical property of ReS_2 and its composite are still necessary to be researched. In this study, for the first time, the ReS_2/reduced graphene oxide (rGO) composites have been synthesized through a facile and one-pot hydrothermal method. The ReS_2/rGO composites exhibit a hierarchical, interconnected, and porous architecture constructed by nanosheets. As anode for lithium-ion batteries, the as-synthesized ReS_2/rGO composites deliver a large initial capacity of 918 mAh g"−"1 at 0.2 C. In addition, the ReS_2/rGO composites exhibit much better electrochemical cycling stability and rate capability than that of bare ReS_2. The significant enhancement in electrochemical property can be attributed to its unique architecture constructed by nanosheets and porous structure, which can allow for easy electrolyte infiltration, efficient electron transfer, and ionic diffusion. Furthermore, the graphene with high electronic conductivity can provide good conductive passageways. The facile synthesis approach can be extended to prepare other 2D transition metal dichalcogenides semiconductors for energy storage and catalytic application.

  19. ResStock Analysis Tool | Buildings | NREL

    Science.gov (United States)

    Energy and Cost Savings for U.S. Homes Contact Eric Wilson to learn how ResStock can benefit your approach to large-scale residential energy analysis by combining: Large public and private data sources uncovered $49 billion in potential annual utility bill savings through cost-effective energy efficiency

  20. Resíduos e contaminantes químicos em alimentos de origem animal no Brasil: histórico, legislação e atuação da vigilância sanitária e demais sistemas regulatórios Chemical residues and contaminants in food of animal origin in Brazil: history, legislation and actions of sanitary surveillance and other regulatory systems

    Directory of Open Access Journals (Sweden)

    Bernardete Ferraz Spisso

    2009-12-01

    Full Text Available A segurança de alimentos é um tema cada vez mais relevante, devido à crescente busca por uma melhor qualidade de vida e conscientização dos consumidores quanto ao direito de adquirir produtos seguros à saúde. O uso de substâncias em animais produtores de alimentos para o consumo humano requer de estudos de farmacocinética à depleção dos resíduos, com o estabelecimento de valores limitativos, de forma que não constituam em um risco à saúde. Além das substâncias utilizadas intencionalmente, outras advindas da contaminação ambiental ou contaminação das rações ingeridas por esses animais podem atingir o homem através da dieta. Os objetivos deste artigo são reunir e discutir os principais atos federais relativos a resíduos e contaminantes químicos em alimentos de origem animal no Brasil, além daqueles relativos ao controle de medicamentos de uso veterinário e aditivos para produtos destinados à alimentação animal. A apresentação cronológica das bases legais pretende facilitar a interpretação dos atos dentro dos respectivos cenários políticos e econômicos. As propostas de ação dos diferentes agentes envolvidos nos sistemas regulatórios são discutidas sob o ponto de vista da saúde pública.Food safety became a relevant subject due to the increasing search for a better way of life and consciousness of the consumers to stand on one's rights to acquire healthy products. The use of substances in animals destined for human consumption requires from pharmacokinetics to residue depletion studies, with the establishment of limitative values so that do not constitute a risk to health. Beyond the substances used deliberately, others coming from environment contamination or contamination of feeding stuffs consumed by these animals may reach human through the diet. The aims of this paper are to collect and discuss the main federal acts covering chemical residues and contaminants in food of animal origin in Brazil

  1. Ethical and regulatory issues with conducting sexuality research with LGBT adolescents: a call to action for a scientifically informed approach.

    Science.gov (United States)

    Mustanski, Brian

    2011-08-01

    Lesbian, gay, bisexual, and transgender (LGBT) adolescents experience disparities in mental and sexual health. There is also a lack of research on this population relative to other adolescents, which limits our ability to effectively address these health disparities. Researchers may unfortunately avoid conducting research with this population because of anticipated or actual experiences with difficulties in obtaining IRB approval. A case example is provided to illustrate the ethical and regulatory issues related to research with LGBT adolescents. Relevant U.S. federal and local regulations related to research on sexual and mental health with adolescents is then reviewed. Data are presented demonstrating that requiring parental consent for LGBT youth under age 18 would likely alter study result. Data are also presented on participants' appraisals of the risks and discomforts associated with research participation. The provision of such empirical data on the risks of research participation is consistent with the goal of moving the IRB process of risk/benefit assessment from being entirely subjective to being evidence-based. Finally, recommendations are provided on how to approach these issues in IRB applications and investigators are called to help to build a corpus of scholarship that can advance empirical knowledge in this area.

  2. Relationship between research and regulatory review in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Kellermann, O.

    1979-01-01

    The current role of all authorities involved in the nuclear safety research programmes is presented. Later this paper discusses the influence of research results on rules, regulations and guidelines for the design of nuclear power plants. (author)

  3. Ethical and regulatory challenges of research using pervasive sensing and other emerging technologies: IRB perspectives.

    Science.gov (United States)

    Nebeker, Camille; Harlow, John; Espinoza Giacinto, Rebeca; Orozco-Linares, Rubi; Bloss, Cinnamon S; Weibel, Nadir

    2017-01-01

    Vast quantities of personal health information and private identifiable information are being created through mobile apps, wearable sensors, and social networks. While new strategies and tools for obtaining health data have expanded researchers' abilities to design and test personalized and adaptive health interventions, the deployment of pervasive sensing and computational techniques to gather research data is raising ethical challenges for Institutional Review Boards (IRBs) charged with protecting research participants. To explore experiences with, and perceptions about, technology-enabled research, and identify solutions for promoting responsible conduct of this research we conducted focus groups with human research protection program and IRB affiliates. Our findings outline the need for increased collaboration across stakeholders in terms of: (1) shared and dynamic resources that improve awareness of technologies and decrease potential threats to participant privacy and data confidentiality, and (2) development of appropriate and dynamic standards through collaboration with stakeholders in the research ethics community.

  4. Safety cases for radioactive waste disposal facilities: guidance on confidence building and regulatory review IAEA-ASAM co-ordinated research project

    International Nuclear Information System (INIS)

    Ben Belfadhel, M.; Bennett, D.G.; Metcalf, P.; Nys, V.; Goldammer, W.

    2008-01-01

    The IAEA has been conducting two co-ordinated research programmes (CRPs) projects to develop and apply improved safety assessment methodologies for near-surface radioactive waste disposal facilities. The more recent of these projects, ASAM (application of safety assessment methodologies), included a Regulatory Review Working Group (RRWG) which has been working to develop guidance on how to gain confidence in safety assessments and safety cases, and on how to conduct regulatory reviews of safety assessments. This paper provides an overview of the ASAM project, focusing on the safety case and regulatory review. (authors)

  5. Optimizing the Nation's Investment in Academic Research: A New Regulatory Framework for the 21st Century

    Science.gov (United States)

    National Academies Press, 2016

    2016-01-01

    Research universities are critical contributors to our national research enterprise. They are the principal source of a world-class labor force and fundamental discoveries that enhance our lives and the lives of others around the world. These institutions help to create an educated citizenry capable of making informed and crucial choices as…

  6. The purifying bridge of Res Publica / Rein Taagepera

    Index Scriptorium Estoniae

    Taagepera, Rein, 1933-

    2004-01-01

    Res Publica edust Eesti poliitilisel maastikul. Autor käsitleb Res Publicat kui puhastava toimega ja silla funktsiooni täitvat parteid, mis üritab siduda tervikuks Keskerakonna ja Reformierakonna seisukohad

  7. Parts ei soovi Res Publica esimehe ametit / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2005-01-01

    Kõige tõenäolisem kandidaat Res Publica juhi kohale on Taavi Veskimägi, aseesimeesteks kandideerivad Marko Mihkelson ja Henn Pärn. Res Publica fraktsiooni koosolekul leidis Mihhail Lotman, et erakond võiks olla feminiinsem

  8. Res Publica meelitab valla- ja linnajuhte / Henrik Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Henrik

    2001-01-01

    Valitsusliidu regionaalpoliitikas pettunud 30 omavalitsusjuhti on astunud ühenduse Res Publica liikmeks, lootes selle põhjal tekkiva partei abil kohaliku ja riigivõimu taas omavahel suhtlema panna. Vt. samas Res Publica liikmetest omavalitsusjuhid

  9. Mastery of Content Representation (CoRes) Related TPACK High School Biology Teacher

    Science.gov (United States)

    Nasution, W. R.; Sriyati, S.; Riandi, R.; Safitri, M.

    2017-09-01

    The purpose of this study was to determine the mastery of Content Representation (CoRes) teachers related to the integration of technology and pedagogy in teaching Biology (TPACK). This research uses a descriptive method. The data were taken using instruments CoRes as the primary data and semi-structured interviews as supporting data. The subjects were biology teacher in class X MIA from four schools in Bandung. Teachers raised CoRes was analyzed using a scoring rubric CoRes with coding 1-3 then categorized into a group of upper, middle, or lower. The results showed that the two teachers in the lower category. This results means that the control of teachers in defining the essential concept in the CoRes has not been detailed and specific. Meanwhile, two other teachers were in the middle category. This means that the ability of teachers to determine the essential concepts in the CoRes are still inadequate so that still needs to be improved.

  10. A report to Congress on Nuclear Regulatory research: Project descriptions for FY87

    International Nuclear Information System (INIS)

    1987-02-01

    The report presents project descriptions of NRC research projects funded in Fiscal Year 1987. The individual project descriptions presented in this report are divided into six major groups of related projects. These groups, called issues, are as follows: Severe Accident, Risk and Reliability, Thermal Hydraulic Transients, Plant Aging and Life Extension, Seismic Research, and Waste Management. Within each issue, the project descriptions are further divided into subgroups, called subissues. An overview is provided prior to each issue and subissue giving a statement of the problem being addressed and the research objectives

  11. The importance of research for the regulatory framework of radiation protection

    International Nuclear Information System (INIS)

    Schmitt-Hannig, A.

    1998-01-01

    On behalf of the Federal ministry for Environment, Nature Conservation and Nuclear Safety (BMU), the Federal Office for Radiation Protection in Germany (BfS) is carrying out a research program in the field of radiation protection. More that 60 research and study contracts in 11 different radiation protection areas are funded every year, and these are carried out mainly by universities and research centers. The results of these projects are used in developing radiation protection regulations, guidelines and procedures to fulfill the special radiation protection tasks of the BMU, the execution of which is required by law. Planning, scientific and administrative management, provision of assistance as well as expert evaluation of the results from these projects lies within the area of responsibility of the BfS. A report issued annually provides information on preliminary and final results of radiation protection research projects in Germany (author) Germany (author)

  12. 78 FR 15953 - Cooperative Agreement To Support Regulatory Research Related to Food and Drug Administration...

    Science.gov (United States)

    2013-03-13

    ... enacted in 1992, has provided FDA with the resources and process enhancements to enable a transformation... performance goals and procedures outlined within PDUFA V will require a high degree of leadership, research...

  13. Juhan Parts soovib Res Publica tagasi tippu viia / Toomas Sildam

    Index Scriptorium Estoniae

    Sildam, Toomas, 1961-

    2004-01-01

    Res Publica esimees peaminister Juhan Parts plaanib minna oma erakonnaga kohalikele valimistele ning uurib võimalusi paremerakondade ühinemiseks. Rakveres toimunud erakonna üldkogust. Lisad: Peaministri neli rasket hetke; Res Publica ministrid said parteilt toetuse. Vt. samas: Reformierakond kiitis Res Publicat hea koostöö eest; Parts: 191 vastuhäält on hea tulemus

  14. Kes tegelikult lõid Res Publica? / Valeri Kalabugin

    Index Scriptorium Estoniae

    Kalabugin, Valeri

    2005-01-01

    Enne erakonnaks kuulutamist oli Res Publica Eesti iseseisvust ja demokraatiat taotlev ühendus, kuhu on kuulunud mitmed poliitika- ning ühiskonnategelased. Vt. samas: Ühendus Res Publica avaldus. Küsimustele vastavad Res Publica avalike suhete juht Riina Vändre, Riigikogu liige Mart Nutt, ajakirjanik Toomas Kümmel

  15. Australia's bio-regulatory framework: leading the way for stem cell research.

    Science.gov (United States)

    Hill, Helen

    2004-01-01

    Biotechnology in Australia has flourished over the past five years. During this time the number of companies has doubled to over 370, and over 40 companies are now publicly listed. The total market capitalization of the biotechnology companies listed on the Australian Stock Exchange (ASX) in 2003 was US$1.5 billion. Total market capitalization of the health and biotech companies on the ASX was US$13 billion. The size of the total Australian pharmaceutical market in 2003 was US$9 billion. This article highlights the role of Australia in advancing stem cell research and its contribution to biotechnology research, development and commercialization.

  16. Stem cell research and therapies in Argentina: the legal and regulatory approach.

    Science.gov (United States)

    de Arzuaga, Fabiana C

    2013-12-01

    Argentina has a significant number of researchers in public and private institutions conducting research in regenerative medicine and stem cells. There is not specific legislation in this area; however, the National Ministry of Health has issued regulations under the scope of the Transplant Act and the Medicines Act. Alongside the groups doing research, it is possible to find professionals offering experimental stem cell therapies to patients. These professionals take refuge in the term "medical practice" and sell experimental treatment to patients with no guarantee of safety and security given that they were not tested in clinical research. These practices offered to patients in a scheme, apparently legal, are generating an important number of judicial actions requesting the payment of said treatments. The decisions of the courts ordering payment in most cases are generating a transfer of funds from patients, social welfare systems, and the state to medical centers offering stem cell experimental therapies. This article describes the current regulations as well as the course of action to solve the emerging problems of these new technologies at legislative level.

  17. Long-range research plan. FY 1987-FY 1991. Volume 3

    International Nuclear Information System (INIS)

    1986-08-01

    The Long-Range Research Plan (LRRP) was prepared by the Office of Nuclear Regulatory Research (RES) to assist the NRC in coordinating its long-range research planning with the short-range budget cycles. The LRRP lays out programmatic approaches for research to help resolve regulatory issues. The plan will be updated annually. It covers: operating reactor inspection, maintenance, and repair; equipment qualification; seismic research; reactor operations and risk; thermal-hydraulic transients; severe accidents; radiation protection and health effects; and waste management

  18. Long-Range Research Plan, FY 1986-FY 1990. Volume 2

    International Nuclear Information System (INIS)

    1985-08-01

    The Long-Range Research Plan (LRRP) was prepared by the Office of Nuclear Regulatory Research (RES) to assist the NRC in coordinating its long-range research planning with the short-range budget cycles. The LRRP lays out programmatic approaches for research to help resolve regulatory issues. The plan will be updated annually. It covers: operating reactor inspection, maintenance, and repair; equipment qualification; seismic research; reactor operations and risk; thermal-hydraulic transients; severe accidents; radiation protection and health effects; and waste management

  19. [Translational/regulatory science researches of NIHS for regenerative medicine and cellular therapy products].

    Science.gov (United States)

    Sato, Yoji

    2014-01-01

    In 2013, the Japanese Diet passed the Regenerative Medicine Promotion Act and the revisions to the Pharmaceutical Affairs Act, which was also renamed as the Therapeutic Products Act (TPA). One of the aims of the new/revised Acts is to promote the development and translation of and access to regenerative/cellular therapies. In the TPA, a product derived from processing cells is categorized as a subgroup of "regenerative medicine, cellular therapy and gene therapy products" (RCGPs), products distinct from pharmaceuticals and medical devices, allowing RCGPs to obtain a conditional and time- limited marketing authorization much earlier than that under the conventional system. To foster not only RCGPs, but also innovative pharmaceuticals and medical devices, the Ministry of Health, Labour and Welfare recently launched Translational Research Program for Innovative Pharmaceuticals, Medical Devices and RCGPs. This mini-review introduces contributions of the National Institute of Health Sciences (NIHS) to research projects on RCGPs in the Program.

  20. Monthly highlights for Office of Nuclear Regulatory Research Programs at Oak Ridge National Laboratory, August 1977

    International Nuclear Information System (INIS)

    Fee, G.G.

    1977-01-01

    Technical highlights are presented for the following safety-related studies: heavy section steel technology, fission product beta and gamma energy release, fission product release from LWR fuel, fission product transport tests, multirod burst tests, Nuclear Safety Information Center, PWR blowdown heat transfer-separate effects, zircaloy fuel cladding collapse studies, zirconium metal-water oxidation kinetics, aerosol release and transport from LMFBR fuel, HTGR safety analysis and research, design criteria for piping and nozzles, and noise diagnostics for safety assessment

  1. Monthly highlights for Office of Nuclear Regulatory research programs at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Fee, G.G.

    1975-04-01

    Summaries are given of the following programs: heavy section steel technology, fission product beta and gamma energy release, LOCA release from LWR fuel, multirod burst tests, Nuclear Safety Information Center, PWR blowdown heat transfer--separate effects, Zircaloy fuel cladding collapse studies, Zr metal--water oxidation kinetics, transient vaporization of LMFBR fuel, and HTGR safety analysis and research. Technical highlights and cost/budget reports are included. (U.S.)

  2. Monthly highlights for Office of Nuclear Regulatory Research Programs at Oak Ridge National Laboratory, August 1976

    International Nuclear Information System (INIS)

    Fee, G.G.

    1976-10-01

    Technical highlights are presented for the following activities: heavy section steel technology, fission product beta and gamma energy release, LOCA release from LWR fuel, Nuclear Safety Information Center, PWR blowdown heat transfer-separate effects, Zircaloy fuel cladding collapse studies, zirconium metal-water oxidation kinetics, aerosol release and transport from LMFBR fuel, HTGR safety analysis and research, design criteria for piping and nozzles, and dose conversion factors for inhalation of radionuclides

  3. Monthly highlights for Office of Nuclear Regulatory Research Programs at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Fee, G.G.

    1976-02-01

    Brief highlights are presented for the following activities: heavy section steel technology program, fission product β and γ energy release, LOCA release from LWR fuel, multirod burst tests, Nuclear Safety Information Center, PWR blowdown heat transfer-separate effects, zircaloy fuel cladding collapse studies, zirconium metal-water oxidation kinetics, aerosol release and transport from LMFBR fuel, HTGR safety analysis and research, and design criteria for piping and nozzles

  4. Immunization in pregnancy clinical research in low- and middle-income countries - Study design, regulatory and safety considerations.

    Science.gov (United States)

    Kochhar, Sonali; Bonhoeffer, Jan; Jones, Christine E; Muñoz, Flor M; Honrado, Angel; Bauwens, Jorgen; Sobanjo-Ter Meulen, Ajoke; Hirschfeld, Steven

    2017-12-04

    Immunization of pregnant women is a promising public health strategy to reduce morbidity and mortality among both the mothers and their infants. Establishing safety and efficacy of vaccines generally uses a hybrid design between a conventional interventional study and an observational study that requires enrolling thousands of study participants to detect an unknown number of uncommon events. Historically, enrollment of pregnant women in clinical research studies encountered many barriers based on risk aversion, lack of knowledge, and regulatory ambiguity. Conducting research enrolling pregnant women in low- and middle-income countries can have additional factors to address such as limited availability of baseline epidemiologic data on disease burden and maternal and neonatal outcomes during and after pregnancy; challenges in recruiting and retaining pregnant women in research studies, variability in applying and interpreting assessment methods, and variability in locally acceptable and available infrastructure. Some measures to address these challenges include adjustment of study design, tailoring recruitment, consent process, retention strategies, operational and logistical processes, and the use of definitions and data collection methods that will align with efforts globally. Copyright © 2017. Published by Elsevier Ltd.

  5. Influence of regulatory requirements for nuclear power plants on the backfitting of Austrian research reactors

    International Nuclear Information System (INIS)

    Boeck, H.; Hammer, J.

    1985-01-01

    In general the licensing and backfitting activities have once more demonstrated the fact that safety assessment of a research reactor is by no means just a scaled-down version of a nuclear power plant licensing procedure. Naturally the risk potential is much lower, however, the very nature of research calls for much more flexibility in operation, for temporary installations and for experimental methods which cannot be covered by detailed regulations in advance. Therefore the application of nuclear power reactor criteria to such facilities has to be considered with extreme caution. If NPP standards are applicable at all, they have to be carefully interpreted in each individual case. It is interesting to compare the original reactor safety reports with their modern versions: emphasis has shifted from reactivity accident calculations to thermal-hydraulic considerations, to better instrumentation (both in quality and quantity) and to more effort in reducing, measuring and documenting all radioactive effluents. This tendency is also reflected in most of the backfitting requirements. In summary, the result of the lengthy licensing and backfitting process is certainly a considerable improvement in performance and safety of the Austrian research reactors

  6. Coordination among industry, academic society and regulatory body in the research on aging management

    International Nuclear Information System (INIS)

    Ishigaki, Hiroki; Osaki, Toru; Kanno, Masanori; Miyano, Hiroshi

    2010-01-01

    Many activities for the coordinated research on aging management are reviewed, and examples of fruitful results are introduced according to the technical strategy map. Industry-Academia-Government exchanging system of the information each other on aging management was established for autonomy, diversity, collaboration. To clarify the concept of the role of industry, government and academia to address aging management without duplication algorithm is for the overall coordination of industrial and academic information and response issues, technological strategy map for aging management formulated. (author)

  7. Making cities energy efficient. Urban and regional planning adopting RES

    Energy Technology Data Exchange (ETDEWEB)

    Ahonen, A.-M.; David, T.; Dorfner, J. [and others

    2013-06-01

    This report summarises the outcomes of a 30 months duration continuing education project entitled 'Urban Planners with Renewable Energy Skills' (UP-RES). The project was carried out by a multi-disciplinary international consortium with the aim of informing planners and related professionals about energy-efficient and CO{sub 2} reducing technologies, practices and systems that can be developed across urban areas to serve whole communities. This report provides an overview of the key issues: The overall project approach to devising a training program based on preceding training needs analysis The key tasks involved in creating the training materials The marketing of the training as well as evaluation results Best practise examples of RES in urban planning. The UP-RES project has focused on several major target groups. These include those groups directly involved in taking forward renewable energy projects for whom the UP-RES training was principally focused; those who wish to deliver such training programmes; and policy makers who are ultimately responsible for the decisions that govern how widely such technologies will be implemented. Each of these groups has its own perspective concerning renewable energy technologies so the report is structured accordingly: For professionals involved in implementation: Among those professions that are likely to become involved with renewable energy initiatives in urban areas are urban planners, architects, energy suppliers, developers, building owners, and consulting engineers. For these professionals chapters 3.2 (summary of training need analysis) and 4 (best practise examples) are most likely to appeal. For training experts and organisations: Training programmes that address the relevance of renewable energies in urban areas require a comprehensive set of materials. As an example of how to organise training courses and lessons learnt, chapter 3 might be interesting. For the generally interested: Renewable energies are

  8. Regulatory aspects of the non-clinical researches in the Isotope Center

    International Nuclear Information System (INIS)

    Castro Alfonso, Yusniel

    2017-01-01

    For the quality control of radiopharmaceuticals produced by Centis and in pharmacokinetic studies carried out in this institution, scintigraphic images of animals are obtained. This allows the assessment of the distribution and behavior of these radiolabeled molecules inside the organism in order to use them in clinical trials in people having different pathologies. Besides following the CNSN regulations involving work with open radioactive sources, non-clinical research laboratory areas are subject to Biosafety Regulations particularly those established by Cecmed. The world trend to integrate the management systems in the organization processes requires the harmonization of Good Laboratory Practices, the compliance with Biosafety Regulations and International Standards concerning the ethics, when working with laboratory animals. This kind of laboratory coordinates its services directly with institutions developing drugs and with the Department of Quality Control for Products used in Nuclear Medicine in Centis. The present work is aimed at assessing the legislation and regulations related with non-clinical research area to take actions intended to improve the integrated management of biosafety for structuring a safety program. (author)

  9. Special committee review of the Nuclear Regulatory Commission's severe accident risks report (NUREG--1150)

    International Nuclear Information System (INIS)

    Kouts, H.J.C.; Apostolakis, G.; Kastenberg, W.E.; Birkhofer, E.H.A.; Hoegberg, L.G.; LeSage, L.G.; Rasmussen, N.C.; Teague, H.J.; Taylor, J.J.

    1990-08-01

    In April 1989, the Nuclear Regulatory Commission's (NRC) Office of Nuclear Regulatory Research (RES) published a draft report ''Severe Accident Risks: An Assessment for Five US Nuclear Power Plants,'' NUREG-1150. This report updated, extended and improved upon the information presented in the 1974 ''Reactor Safety Study,'' WASH-1400. Because the information in NUREG-1150 will play a significant role in implementing the NRC's Severe Accident Policy, its quality and credibility are of critical importance. Accordingly, the Commission requested that the RES conduct a peer review of NUREG-1150 to ensure that the methods, safety insights and conclusions presented are appropriate and adequately reflect the current state of knowledge with respect to reactor safety. To this end, RES formed a special committee in June of 1989 under the provisions of the Federal Advisory Committee Act. The Committee, composed of a group of recognized national and international experts in nuclear reactor safety, was charged with preparing a report reflecting their review of NUREG-1150 with respect to the adequacy of the methods, data, analysis and conclusions it set forth. The report which precedes reflects the results of this peer review

  10. Farm Shop : Augmenter l'accès aux matières premières agricoles au ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Farm Shop est un modèle de franchise social novateur qui permet d'obtenir des matières premières d'excellente qualité à des prix abordables grâce à des économies d'échelle. Il forme également des franchisés et des agriculteurs sur la façon d'utiliser les matières premières. Au cours de ses trois premières années ...

  11. [Advance in research on regulatory mechanism and functions of neutral sphingomyelinse 2].

    Science.gov (United States)

    Zhang, Lan; Guo, Jun

    2013-10-01

    Neutral sphingomyelinase 2 (nSMase2), which located mainly on the plasma membrane, hydrolyzes sphingomyelin into ceramide and plays an important role in the physiological and pathological regulation of cell apoptosis, cell growth arrest, and inflammation. nSMase2 is also involved in the development of Alzheimer's disease and the bone growth.Under neutral pH and the presence of Ca(2+), Mg(2+), and Mn(+), the activity of nSMase2 is induced by oxidative stress through phosphorylation. Furthermore, the induced interaction of anionic phospholipids and the signaling molecules like receptor for activated C-kinase 1/embryonic ectodermal development with nSMase2 are also crucial mechanisms of protein activation. In the review, recent research advances in the structure and function of nSMase2 and its underlying mechanisms are summarized.

  12. Introductory user's manual for the US Nuclear Regulatory Commission Reactor Safety Research Data Bank

    International Nuclear Information System (INIS)

    Scofield, N.R.; Hardy, H.A.; Laats, E.T.

    1984-03-01

    The United States NRC has established the NRC/Division of Accident Evaluation (DAE) Data Bank Program to collect, store, and make available data from the many domestic and foreign water reactor safety research programs. Local direction of the program is provided by EG and G Idaho, Inc., prime contractor for the Department of Energy (DOE) at the Idaho National Engineering Laboratory (INEL). The NRC/DAE Data Bank Program provides a central computer storage mechanism and access software for data that is to be used by code development and assessment groups in meeting the code and correlation needs of the nuclear industry. The administrative portion of the program provides data entry, documentation, training, and advisory services to users and the NRC. The NRC/DAE Data Bank and the capabilities of the data access software are described in this document

  13. U.S. Nuclear Regulatory Commission seismic regulations, research, and emerging trends

    Energy Technology Data Exchange (ETDEWEB)

    Chokshi, N C; Shao, L C [Nuclear Regulatory Commission, Washington, DC (United States). Office of Nuclear Regulatory Research; Apostolakis, G

    1997-03-01

    Historically in the United States, seismic issues have played an important role in determining site suitability and, in some cases, have determined the ultimate fate of power plants. During the late 1960s and early 1970s, a seismic design philosophy evolved as the licensing of the earlier plants was in progress. Concepts such as the Safe Shutdown Earthquake (SSE) and the Operating Basis Earthquake (OBE) emerged and were codified into the federal regulations with the publication in December 1973 of Appendix A, `Seismic and Geologic Siting Criteria for Nuclear Power Plants,` to 10 CFR Part 100, `Reactor Site Criteria.` Seismic considerations are also important in siting and design of other fuel cycle and waste facilities. In this paper, a brief overview of the current seismic siting and design regulations are described along with some recent and planned changes based on the past experience, advancement in the state-of-the-art, and research results. In particular, the recently revised siting rule and use of the probabilistic seismic hazard analysis in implementation of the rule will be described in more detail. The paper includes discussion of some recent seismic issues and research activities, including issues related to aging. Some emerging trends are highlighted. In particular, the paper focuses on use of `expert opinion` in the probabilistic analysis and risk informed regulations and their implications to the seismic design. An additional focus is on international cooperative programs and how to initiate such programs such that better use can be made of limited resources to resolve issues of common interest. (author)

  14. U.S. Nuclear Regulatory Commission seismic regulations, research, and emerging trends

    International Nuclear Information System (INIS)

    Chokshi, N.C.; Shao, L.C.; Apostolakis, G.

    1997-01-01

    Historically in the United States, seismic issues have played an important role in determining site suitability and, in some cases, have determined the ultimate fate of power plants. During the late 1960s and early 1970s, a seismic design philosophy evolved as the licensing of the earlier plants was in progress. Concepts such as the Safe Shutdown Earthquake (SSE) and the Operating Basis Earthquake (OBE) emerged and were codified into the federal regulations with the publication in December 1973 of Appendix A, 'Seismic and Geologic Siting Criteria for Nuclear Power Plants,' to 10 CFR Part 100, 'Reactor Site Criteria.' Seismic considerations are also important in siting and design of other fuel cycle and waste facilities. In this paper, a brief overview of the current seismic siting and design regulations are described along with some recent and planned changes based on the past experience, advancement in the state-of-the-art, and research results. In particular, the recently revised siting rule and use of the probabilistic seismic hazard analysis in implementation of the rule will be described in more detail. The paper includes discussion of some recent seismic issues and research activities, including issues related to aging. Some emerging trends are highlighted. In particular, the paper focuses on use of 'expert opinion' in the probabilistic analysis and risk informed regulations and their implications to the seismic design. An additional focus is on international cooperative programs and how to initiate such programs such that better use can be made of limited resources to resolve issues of common interest. (author)

  15. Individual air pollution monitors. 2. Examination of some nonoccupational research and regulatory uses and needs

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, M.G.; Morris, S.C.

    1977-01-01

    Knowledge of the relationship between ambient air pollution levels measured at fixed monitoring stations and the actual exposure of the population is very limited. Indeed, there is rapidly growing evidence that fixed-station monitors do not provide adequate data for population exposure. This report examines available data for carbon monoxide (CO) and sulfur dioxide (SO/sub 2/) and presents a new analysis. Actual population exposure to CO appears to be consistently higher than expected from fixed-station data, while limited evidence suggests that exposures to SO/sub 2/ are lower. A reported general relationship between indoor and outdoor levels of SO/sub 2/ is not supported by the data. If air pollution represents a threat to public health, then more attention must be given to total population exposure to pollutants. A selective use of individual air pollution monitors that can be worn or carried appears to be required at some stage by any experimental design seeking to uncover the relation between air pollution exposure and health effects. Additionally, potential uses of individual monitoring in air pollution regulation are explored. Current status and research needs for individual air pollution monitors are examined and a first-order evaluation is given of the promise held by the candidate instrumentation technologies. A national program of support for the development of individual air pollution monitors is recommended.

  16. Scientific research and regulatory control: An interaction that must be reviewed

    International Nuclear Information System (INIS)

    Nouailhetas, Y.; Mezrahi, A.; Bonacossa Almeida, C.E. de; Xavier, A.M.

    1997-01-01

    The control of radiological impact, in Brazil, at nuclear facilities is based on radiological protection guidelines adopted by the Nuclear Energy National Commission (CNEN), following recommendations of the International Commission on Radiological Protection (ICRP), Publication 26. ICRP adopted ''prudently'', for radiological protection purposes, the hypothesis, in case of stochastic effects, of linearity dose/effect, without dose threshold, based on absence of conclusive data concerning the real behaviour of dose/effect curve. Additionally, the position of ICRP is not sustained specially considering as non existent individually accumulated doses, accumulated doses through generations and origin of radiation, either natural or anthropogenic. Brazil follows ICRP recommendations despite existing high background radiation areas. In absence of a definitive position, professionals of different areas, such as jurists and psychologists infer on ''effects of radiation'', no matter it exists. ICRP should: clarify as being just operational linearity hypothesis; consider that an excess of prudence can cause a non-sense public rejection to nuclear applications; incentive participation of different fields scientists to elaborate radiological protection procedures and radiological protection scientists to develop researches based on realistic data. Finally, it would be possible to achieve a new philosophy for public protection considering real risks associated with exposure to radiation. (author)

  17. Research and development and related capabilities for safety and licensing of nuclear power reactors: a regulatory perspective

    International Nuclear Information System (INIS)

    Newland, D.B.

    2001-01-01

    In today's increasingly competitive environment within the electrical power generation industry, the nuclear power utilities are constantly striving for greater efficiency and lower operating costs. Economic de-regulation costs. Economic de-regulation of the electrical market is occurring in a number of countries, including Canada, and this places additional pressure on utilities to be economically competitive. The industry examines all its business activities critically to determine if they provide benefit and good value for money. In these circumstances there can be a tendency for the longer term strategic activities to be treated as lower priority and have reduced funding. Such activities include research and development, design authority, corporate knowledge, and technical expertise, and their associated infrastructure. This paper discusses how the situation with regard to funding of research and development (R and D) has evolved in Canada over the past 5 years, and how the Canadian Nuclear Safety Commission (CNSC) has responded to the changing environment. Of particular interest is a R and D capability review that the industry undertook, the results of which are briefly described. Other related infrastructure aspects such as technical expertise, design authority, education and their inter-relationship with R and D. are also discussed. There are a number of important elements that are needed for a successful way forward: recognition of the depth of the problem by stakeholders; clarification of the roles and responsibilities of these stakeholders; strong leadership within the power reactor industry; improved co-ordinating amongst the industry partners; effective international co-operation; and succession planning in the broadest sense. It is finally concluded that the issue of R and D funding and expertise maintenance is one that will not go away and will inevitably worsen. It is a difficult issue to tackle and there are no simple solutions. The situation has

  18. RES-E-NEXT: Next Generation of RES-E Policy Instruments

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.; Bird, L.; Cochran, J.; Milligan, M.; Bazilian, M. [National Renewable Energy Laboratory, Golden, CO (United States); Denny, E.; Dillon, J.; Bialek, J.; O’Malley, M. [Ecar Limited (Ireland); Neuhoff, K. [DIW Berlin (Germany)

    2013-07-04

    The RES-E-NEXT study identifies policies that are required for the next phase of renewable energy support. The study analyses policy options that secure high shares of renewable electricity generation and adequate grid infrastructure, enhance flexibility and ensure an appropriate market design. Measures have limited costs or even save money, and policies can be gradually implemented.

  19. Regulatory agencies and regulatory risk

    OpenAIRE

    Knieps, Günter; Weiß, Hans-Jörg

    2008-01-01

    The aim of this paper is to show that regulatory risk is due to the discretionary behaviour of regulatory agencies, caused by a too extensive regulatory mandate provided by the legislator. The normative point of reference and a behavioural model of regulatory agencies based on the positive theory of regulation are presented. Regulatory risk with regard to the future behaviour of regulatory agencies is modelled as the consequence of the ex ante uncertainty about the relative influence of inter...

  20. An Exploration of the Legal and Regulatory Environment of Privacy and Security through Active Research, Guided Study, Blog Creation, and Discussion

    Science.gov (United States)

    Peslak, Alan R.

    2010-01-01

    One of the most important topics for today's information technology professional is the study of legal and regulatory issues as they relate to privacy and security of personal and business data and identification. This manuscript describes the topics and approach taken by the instructors that focuses on independent research of source documents and…

  1. Systematic assessment of benefits and risks: study protocol for a multi-criteria decision analysis using the Analytic Hierarchy Process for comparative effectiveness research [v1; ref status: indexed, http://f1000r.es/1fk

    Directory of Open Access Journals (Sweden)

    Nisa M Maruthur

    2013-07-01

    Full Text Available Background: Regulatory decision-making involves assessment of risks and benefits of medications at the time of approval or when relevant safety concerns arise with a medication. The Analytic Hierarchy Process (AHP facilitates decision-making in complex situations involving tradeoffs by considering risks and benefits of alternatives. The AHP allows a more structured method of synthesizing and understanding evidence in the context of importance assigned to outcomes. Our objective is to evaluate the use of an AHP in a simulated committee setting selecting oral medications for type 2 diabetes.  Methods: This study protocol describes the AHP in five sequential steps using a small group of diabetes experts representing various clinical disciplines. The first step will involve defining the goal of the decision and developing the AHP model. In the next step, we will collect information about how well alternatives are expected to fulfill the decision criteria. In the third step, we will compare the ability of the alternatives to fulfill the criteria and judge the importance of eight criteria relative to the decision goal of the optimal medication choice for type 2 diabetes. We will use pairwise comparisons to sequentially compare the pairs of alternative options regarding their ability to fulfill the criteria. In the fourth step, the scales created in the third step will be combined to create a summary score indicating how well the alternatives met the decision goal. The resulting scores will be expressed as percentages and will indicate the alternative medications' relative abilities to fulfill the decision goal. The fifth step will consist of sensitivity analyses to explore the effects of changing the estimates. We will also conduct a cognitive interview and process evaluation.  Discussion: Multi-criteria decision analysis using the AHP will aid, support and enhance the ability of decision makers to make evidence-based informed decisions consistent

  2. A Case Study of the Impediments to the Commercialization of Research at the University of Kentucky [v2; ref status: indexed, http://f1000r.es/5pi

    Directory of Open Access Journals (Sweden)

    Nathan L. Vanderford

    2015-08-01

    Full Text Available The commercialization of university-based research occurs to varying degrees between academic institutions. Previous studies have found that multiple barriers can impede the effectiveness and efficiency by which academic research is commercialized. This case study was designed to better understand the impediments to research commercialization at the University of Kentucky via a survey and interview with three successful academic entrepreneurs. The study also garnered insight from the individuals as to how the commercialization process could be improved. Issues with commercialization infrastructure; a lack of emphasis, at the university level, on the importance of research commercialization; a void in an entrepreneurial culture on campus; inhibitory commercialization policies; and a lack of business and commercialization knowledge among faculty were highlighted as the most significant barriers. The research subjects also suggested that commercialization activity may generally increase if a number of factors were mitigated. Such insight can be communicated to the administrative leadership of the commercialization process at the University of Kentucky. Long term, improving university-based research commercialization will allow academic researchers to be more active and successful entrepreneurs such that intellectual property will progress more freely to the marketplace for the benefit of inventors, universities and society.

  3. Afrique : ressources minières, environnement et gouvernance ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    25 janv. 2011 ... ils regorgent de richesses inouïes », assure Bonnie Campbell, directrice du Groupe de recherche sur les activités minières en Afrique (GRAMA) et titulaire de la Chaire C.-A. Poissant de recherche sur la gouvernance et l'aide au développement, faisant référence aux ressources minières et pétrolières dont ...

  4. Resúmenes de proyectos de grado

    Directory of Open Access Journals (Sweden)

    Revista Ingeniería e Investigación

    2002-01-01

    Full Text Available Para la Facultad de Ingeniería de la Universidad Nacional de Colombia sede Bogotá los trabajos desarrollados por los estudiantes con la dirección de docentes como condición para obtener su título profesional, expresan la dinámica de las investigaciones y las áreas de conocimiento en la que están comprometidos los diferentes estamentos de la facultad, Es por esta razón que la revista Ingeniería e Investigación comenzará a publicar, a partir de la fecha los resúmenes de los trabajos de pregrado y las tesis de posgrado que permanentemente se están desarrollando en la Facultad de Ingeniería.

  5. Res Publica Euroopas / Eiki Berg, Marko Mihkelson ; interv. Lauri Lugna

    Index Scriptorium Estoniae

    Berg, Eiki, 1970-

    2003-01-01

    Res Publica välispoliitika eksperdid Eiki Berg ja Marko Mihkelson vastavad küsimustele, mis käsitlevad Res Publica saamist Euroopa Rahvapartei (ERP) liikmeks, koostööd ERP-ga, EL-i põhiseaduslikku lepet

  6. Res Publica viskab Oleg Rebase välja

    Index Scriptorium Estoniae

    2006-01-01

    Res Publica Tallinna piirkonna juhatus leidis, et Oleg Rebane läks Keskerakonna provokatsiooniga kaasa minnes vastuollu Res Publica põhimõtetega. Tallinna linnapea Jüri Ratase suhtes algatatud umbusaldushääletuse põhjustest. Sven Sester vastab küsimusele, mis seotud Oleg Rebase ja Tõnis Bittmani juhtumiga

  7. Journal ratings as predictors of articles quality in Arts, Humanities and Social Sciences: an analysis based on the Italian Research Evaluation Exercise [v1; ref status: indexed, http://f1000r.es/5d3

    Directory of Open Access Journals (Sweden)

    Andrea Bonaccorsi

    2015-07-01

    Full Text Available The aim of this paper is to understand whether the probability of receiving positive peer reviews is influenced by having published in an independently assessed, high-ranking journal: we eventually interpret a positive relationship among peer evaluation and journal ranking as evidence that journal ratings are good predictors of article quality. The analysis is based on a large dataset of over 11,500 research articles published in Italy in the period 2004-2010 in the areas of architecture, arts and humanities, history and philosophy, law, sociology and political sciences. These articles received a score by a large number of externally appointed referees in the context of the Italian research assessment exercise (VQR; similarly, journal scores were assigned in a panel-based independent assessment, which involved all academic journals in which Italian scholars have published, carried out under a different procedure. The score of an article is compared with that of the journal it is published in: more specifically, we first estimate an ordered probit model, assessing the probability for a paper of receiving a higher score, the higher the score of the journal; in a second step, we concentrate on the top papers, evaluating the probability of a paper receiving an excellent score having been published in a top-rated journal. In doing so, we control for a number of characteristics of the paper and its author, including the language of publication, the scientific field and its size, the age of the author and the academic status. We add to the literature on journal classification by providing for the first time a large scale test of the robustness of expert-based classification.

  8. Occupational Radiation Exposure at Commercial Nuclear Power Reactors and Other Facilities 2010, Prepared for the Nuclear Regulatory Commission, Office of Nuclear Regulatory Research, May 2012

    Energy Technology Data Exchange (ETDEWEB)

    D. E. Lewis D. A. Hagemeyer Y. U. McCormick

    2012-07-07

    This report summarizes the occupational exposure data that are maintained in the U.S. Nuclear Regulatory Commission’s (NRC) Radiation Exposure Information and Reporting System (REIRS). The bulk of the information contained in the report was compiled from the 2010 annual reports submitted by five of the seven categories of NRC licensees subject to the reporting requirements of 10 CFR 20.2206. Because there are no geologic repositories for high-level waste currently licensed and no NRC-licensed low-level waste disposal facilities currently in operation, only five categories will be considered in this report. The annual reports submitted by these licensees consist of radiation exposure records for each monitored individual. These records are analyzed for trends and presented in this report in terms of collective dose and the distribution of dose among the monitored individuals. Annual reports for 2010 were received from a total of 190 NRC licensees. The summation of reports submitted by the 190 licensees indicated that 192,424 individuals were monitored, 81,961 of whom received a measurable dose. When adjusted for transient workers who worked at more than one licensee during the year, there were actually 142,471 monitored individuals and 62,782 who received a measurable dose. The collective dose incurred by these individuals was 10,617 person-rem, which represents a 12% decrease from the 2009 value. This decrease was primarily due to the decrease in collective dose at commercial nuclear power reactors, as well as a decrease in the collective dose for most of the other categories of NRC licensees. The number of individuals receiving a measurable dose also decreased, resulting in an average measurable dose of 0.13 rem for 2010. The average measurable dose is defined as the total effective dose equivalent (TEDE) divided by the number of individuals receiving a measurable dose. In calendar year 2010, the average annual collective dose per reactor for light water reactor

  9. Twenty-third water reactor safety information meeting. Volume 3, structural and seismic engineering, primary systems integrity, equipment operability and aging, ECCS strainer blockage research and regulatory issues

    Energy Technology Data Exchange (ETDEWEB)

    Monteleone, S. [comp.] [Brookhaven National Lab., Upton, NY (United States)

    1996-03-01

    This three-volume report contains papers presented at the Twenty- Third Water Reactor Safety Information Meeting held at the Bethesda Marriott Hotel, Bethesda, Maryland, October 23-25, 1995. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Italy, Japan, Norway, Russia, Sweden, and Switzerland. This document, Volume 3, presents topics in Structural & Seismic Engineering, Primary Systems Integrity, Equipment Operability and Aging, and ECCS Strainer Blockage Research & Regulatory Issues. Individual papers have been cataloged separately.

  10. Twenty-third water reactor safety information meeting. Volume 3, structural and seismic engineering, primary systems integrity, equipment operability and aging, ECCS strainer blockage research and regulatory issues

    International Nuclear Information System (INIS)

    Monteleone, S.

    1996-03-01

    This three-volume report contains papers presented at the Twenty- Third Water Reactor Safety Information Meeting held at the Bethesda Marriott Hotel, Bethesda, Maryland, October 23-25, 1995. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Italy, Japan, Norway, Russia, Sweden, and Switzerland. This document, Volume 3, presents topics in Structural ampersand Seismic Engineering, Primary Systems Integrity, Equipment Operability and Aging, and ECCS Strainer Blockage Research ampersand Regulatory Issues. Individual papers have been cataloged separately

  11. Regulatory activities

    International Nuclear Information System (INIS)

    2001-01-01

    This publication, compiled in 8 chapters, presents the regulatory system developed by the Nuclear Regulatory Authority (NRA) of the Argentine Republic. The following activities and developed topics in this document describe: the evolution of the nuclear regulatory activity in Argentina; the Argentine regulatory system; the nuclear regulatory laws and standards; the inspection and safeguards of nuclear facilities; the emergency systems; the environmental systems; the environmental monitoring; the analysis laboratories on physical and biological dosimetry, prenatal irradiation, internal irradiation, radiation measurements, detection techniques on nuclear testing, medical program on radiation protection; the institutional relations with national and international organization; the training courses and meeting; the technical information

  12. Power utility generation portfolio optimization as function of specific RES and decarbonisation targets – EPBiH case study

    International Nuclear Information System (INIS)

    Kazagic, Anes; Merzic, Ajla; Redzic, Elma; Music, Mustafa

    2014-01-01

    Highlights: • Guidelines for power utilities to reach specific decarbonisation targets offered. • Optimization model of RES share to be introduced into power system is proposed. • Single criteria analysis and multicriteria sustainability assessment are applied. • The optimization method has been demonstrated on a real power system. • In the considered case, HIGH RES scenario showed to be the preferable one. - Abstract: This paper provides guidelines and principles for power utilities to reach specific energy and decarbonisation targets. Method of power generation portfolio optimization, as function of sustainability and decarbonisation, along with appropriate criteria, has been proposed. Application of this optimization method has been demonstrated on a real power system – power utility JP Elektroprivreda BiH d.d. – Sarajevo (EPBiH), a typical example of South East European power system. The software tool WASP IV has been employed in the analysis, in order to define the dynamics and an optimized expansion of generation portfolio of the power system under consideration for the next period. The mid-term generation portfolio development plan for the EPBiH power system until year 2030 has been made during this research, taking into account the shutdown dynamics of existing power units and commissioning new ones, in order to provide safe supply of electric and heat energy for local consumers. Three basic scenario of renewable energy sources (RES) expansion have been analysed to reach specific RES and decarbonisation targets set for 2030, including RES share increase from the current level of 18% up to 35% (LOW RES), 45% (MID RES) and 55% (HIGH RES). Effects to the sustainability are considered through environmental, economic and social indicators. Multicriteria sustainability assessment gave an advantage to the HIGH RES, under assumption of equal weighting factors of economic and environment groups of indicators. Also, single criteria analysis has been

  13. Long-Range Research Plan, FY 1985-FY 1989

    International Nuclear Information System (INIS)

    1984-09-01

    The Long-Range Research Plan (LRRP) was prepared by the Office of Nuclear Regulatory Research (RES) to assist the NRC in coordinating its long-range research planning with the short-range budget cycles. The LRRP lays out programmatic approaches for research to help resolve regulatory issues. The plan will be updated annually. This document is divided into the following sections: operating reactor inspection, maintenance, and repair; equipment qualification; seismic research; reactor operations and risk; thermal-hydraulic transients; severe accidents; advanced concepts; radiation protection and health effects; and waste management. The following are also listed as appendices: unresolved safety issues and TMI action plan items, priorities for research program, research program outline, and research utilization report. A glossary of acronyms is included

  14. Gestão de resíduos sólidos em restaurante escola

    Directory of Open Access Journals (Sweden)

    Bianca Peruchin

    2013-01-01

    Full Text Available Um dos maiores problemas ambientais da atualidade é a excessiva geração de resíduos e a sua destinação final ambientalmente adequada. As Instituições de Ensino Superior (IES são importantes fontes geradoras devido à diversidade de atividades de ensino, pesquisa e extensão realizadas no seu âmbito. Os Restaurantes Escola (RE atendem à comunidade acadêmica dos campi universitários, e caracterizam-se por produzir resíduos similares aos domésticos, mas em maior quantidade. Este estudo foi realizado com o objetivo de investigar a composição gravimétrica dos resíduos produzidos em um RE de uma IES localizada no sul do país, bem como conhecer a situação atual do gerenciamento dos resíduos. Os dados foram obtidos através da caracterização dos resíduos do RE durante cinco dias, de entrevista com os gestores responsáveis pelo estabelecimento e da observação direta no local. Averiguou-se a inexistência de um Plano de Gerenciamento dos Resíduos Sólidos no RE, bem como a ausência de práticas efetivas relacionadas ao manejo destes. A segregação dos resíduos é prejudicada devido à falta de lixeiras específicas e a sobrecarga dos funcionários quanto às atividades desempenhadas. Ao longo do período experimental foram caracterizados 547,068 Kg de resíduos, dos quais mais de 80% corresponderam à matéria orgânica. Conclui-se que o montante de resíduo orgânico gerado pode ser destinado à compostagem. Recomenda-se a implantação de uma infraestrutura adequada para o manejo dos resíduos, que pode ser feita através da elaboração e aplicação de um plano de gestão integrada dos resíduos sólidos no RE.Abstract Nowadays, the amount of waste generated and its proper final destination is one of the greatest environmental issues. Higher education institutions are an important source of waste due to the diversity of teaching, researching and extension activities performed in their facilities. The university

  15. Nuclear power plant thermal-hydraulic performance research program plan

    International Nuclear Information System (INIS)

    1988-07-01

    The purpose of this program plan is to present a more detailed description of the thermal-hydraulic research program than that provided in the NRC Five-Year Plan so that the research plan and objectives can be better understood and evaluated by the offices concerned. The plan is prepared by the Office of Nuclear Regulatory Research (RES) with input from the Office of Nuclear Reactor Regulation (NRR) and updated periodically. The plan covers the research sponsored by the Reactor and Plant Systems Branch and defines the major issues (related to thermal-hydraulic behavior in nuclear power plants) the NRC is seeking to resolve and provides plans for their resolution; relates the proposed research to these issues; defines the products needed to resolve these issues; provides a context that shows both the historical perspective and the relationship of individual projects to the overall objectives; and defines major interfaces with other disciplines (e.g., structural, risk, human factors, accident management, severe accident) needed for total resolution of some issues. This plan addresses the types of thermal-hydraulic transients that are normally considered in the regulatory process of licensing the current generation of light water reactors. This process is influenced by the regulatory requirements imposed by NRC and the consequent need for technical information that is supplied by RES through its contractors. Thus, most contractor programmatic work is administered by RES. Regulatory requirements involve the normal review of industry analyses of design basis accidents, as well as the understanding of abnormal occurrences in operating reactors. Since such transients often involve complex thermal-hydraulic interactions, a well-planned thermal-hydraulic research plan is needed

  16. Res Publica lükkas tagasi Isamaaliidu ühinemisettepaneku / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2005-01-01

    Kuigi Res Publica juhid lükkasid tagasi idee ühineda Isamaaliiduga, on Res Publica valmis koostööks nii Isamaaliidu kui ka kõigi teiste erakondadega. Res Publica parlamendifraktsiooni esimehe Marko Pomerantsi arvamus

  17. Time-Line in HFEA Developments and Regulatory Challenges: 20 Years of Overseeing Fertility Practices and Research in the UK.

    Science.gov (United States)

    Agrawal, Rina; Burt, Elizabeth; Homburg, Roy

    2013-12-01

    In the wake of political upheaval, the Human Fertilisation and Embryo Authority (HFEA) has faced increasing insecurity over its future as a pivotal regulatory body of fertility practices in the UK. HFEA regulates activities by means of licensing, audit, and inspection of fertility centers and maintaining the Code of Practice, which ensures the optimum undertaking of licensed activities by fertility centers. In 2009, amendments to the 1990 Act came into force representing an amalgamation of cumulative proposals, debates, and changes in legislation, which have shaped the world of reproductive medicine. The medical world has, in many cases, adapted to righteous political and social demands, and continues to evolve at a rapid rate. The HFEA has faced many regulatory challenges and changes, and through this study, we aim to provide an overview of some of these changes, particularly those during the last 10 years and the implications that they may have had to fertility practices.

  18. Regulatory Considerations for the Clinical and Research Use of Transcranial Direct Current Stimulation (tDCS): review and recommendations from an expert panel

    Science.gov (United States)

    Fregni, F; Nitsche, MA; Loo, C.K.; Brunoni, AR; Marangolo, P; Leite, J; Carvalho, S; Bolognini, N; Caumo, W; Paik, NJ; Simis, M; Ueda, K; Ekhitari, H; Luu, P; Tucker, DM; Tyler, WJ; Brunelin, J; Datta, A; Juan, CH; Venkatasubramanian, G; Boggio, PS; Bikson, M

    2014-01-01

    The field of transcranial electrical stimulation (tES) has experienced significant growth in the past 15 years. One of the tES techniques leading this increased interest is transcranial direct current stimulation (tDCS). Significant research efforts have been devoted to determining the clinical potential of tDCS in humans. Despite the promising results obtained with tDCS in basic and clinical neuroscience, further progress has been impeded by a lack of clarity on international regulatory pathways. We therefore convened a group of research and clinician experts on tDCS to review the research and clinical use of tDCS. In this report, we review the regulatory status of tDCS, and we summarize the results according to research, off-label and compassionate use of tDCS in the following countries: Australia, Brazil, France, Germany, India, Iran, Italy, Portugal, South Korea, Taiwan and United States. Research use, off label treatment and compassionate use of tDCS are employed in most of the countries reviewed in this study. It is critical that a global or local effort is organized to pursue definite evidence to either approve and regulate or restrict the use of tDCS in clinical practice on the basis of adequate randomized controlled treatment trials. PMID:25983531

  19. Long-term Field Experiments as Important Source of Knowledge - Aims of the BonaRes Data Centre

    Science.gov (United States)

    Grosse, Meike; Hierold, Wilfried

    2017-04-01

    BonaRes is short for "soil as a sustainable resource for the bioeconomy". It is funded by the German Federal Ministry of Education and Research (BMBF) under the umbrella of the National Research Strategy BioEconomy 2030. BonaRes consists of ten interdisciplinary research project consortia and the 'BonaRes - Centre for Soil Research' (see also Wollschläger et al 2016). It is one task of the BonaRes Data Centre as part of the 'BonaRes - Centre for Soil Research', to collect data and meta-data of agricultural long-term field experiments (LTFE) in Germany. The definition of LTFE in the context of BonaRes is a minimum duration of twenty years and a static design. LTFE are essential research infrastructures for agricultural sciences and soil sciences amongst other disciplines. Some LTFE run since a very long time; the start of the oldest one in Germany was 1878. Therefore, in many cases valuable time series exist. Data sets of LTFE shall be compiled and made publicly available by the BonaRes Data Centre. The public availability together with an easy access will lead to an enhanced usability of the data. This probably makes the LTFE itself more valuable through an improved visibility and may also help to maintain the LTFE. Beyond the data compilation there is the possibility for every data owner to make a data publication, which offers an additional value for the data owner after his first right of use. A first step towards a joint database is a compilation of all existing LTFE in Germany with meta information to each trial. This information is shown in an interactive web map, what is completely new in that context. Besides the exact position of the LTFE the following metadata are shown: name of the LTFE, website (if available), institution, land use category, participation in existing networks, research theme, start (and maybe end) of the trial, and research parameters. Details on the meta information will be presented in the speech. Literature Wollschläger, U; Helming

  20. Isamaa ja Res Publica Liidu plaan / Juhan Parts

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2008-01-01

    Ilmunud ka: Eesti Eest = Za Estoniju : Izdanije objedinenija "Sojuz Otetshestva i Res Publica" 15. mai 2008, lk. 4-5. Eesti majanduse uutest ülesannetest. Kommenteerib: Mart Laar. Vt. samas: IRL-i ettepanekud koalitsioonileppe täienduseks

  1. Comentário sobre as Res Gestae Divi Avgvsti

    Directory of Open Access Journals (Sweden)

    Maria Luiza Corassin

    2004-12-01

    Full Text Available This article studies an epigraphic source, Augustus's Res gestae, which provides elements that elucidate the construction of the imperial power system and the relationship between ruler and ruled.

  2. Comment rendre les villes plus sûres

    International Development Research Centre (IDRC) Digital Library (Canada)

    qui travaillent à l'initiative Villes sûres et inclusives font la lumière sur ce qui fonctionne – et ne fonctionne pas – pour rendre les villes plus sûres. Le présent compte rendu comporte certains enseignements tirés de leur travail, ainsi que les lacunes dans les connaissances et les domaines où il faut poursuivre la recherche.

  3. Annual report to the Atomic Energy Control Board on the Regulatory Research and Support Program April 1, 1994 - March 31, 1995

    International Nuclear Information System (INIS)

    1996-03-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend activities, undertaken by the Atomic Energy Control Board, beyond what would be possible with in-house resources. The overall objective of the research and support activity is to produce pertinent and independent information that will assist the Board and its staff in making sound, timely and credible decisions for the regulation of nuclear facilities and materials. During Fiscal Year 1994/95, a total of $3.245M was spent of RSP research and support work. The range of activities included projects in the general fields of nuclear reactors, fuel cycle facilities, uranium mines and mills, waste management, dosimetry, health physics, regulations and regulatory process development, and other special support services. Some of this work was organized into sub-program groups, each of which addresses research and support effort in theme-related areas. Five sub-programs were launched during the year bringing to eight the total number of such sub-programs. Areas addressed in the sub-programs are environmental impact assessment and management, safety critical software, seismologic studies, pressure boundary integrity, integrity of containment and safety-related structures, human factors, internal dosimetry, and health effects in human populations. During the year, there were a total of 157 active projects

  4. Regulatory review and confidence building in post-closure safety assessments and safety cases for near surface disposal facilities-IAEA ASAM coordinated research programme

    International Nuclear Information System (INIS)

    Gonzales, A.; Simeonov, G.; Bennett, D.G.; Nys, V.; Ben Belfadhel, M.

    2005-01-01

    Some years ago, the IAEA successfully concluded a Coordinated Research Program (CRP) called Islam, which focussed on the development of an Improved Safety Assessment Methodology for near-surface radioactive waste disposal facilities. In November 2002, and as an extension of ISAM, the IAEA launched a new CRP called ASAM, designed to test the Application of the Safety Assessment Methodology by considering a range of near-surface disposal facilities. The ASAM work programme is being implemented by three application working groups and two cross-cutting working groups. The application working groups are testing the applicability of the ISAM methodology by assessing an existing disposal facility in Hungary, a copper mine in South Africa, and a hypothetical facility containing heterogenous wastes, such as disused sealed sources. The first cross-cutting working group is addressing a number of technical issues that are common to all near-surface disposal facilities, while the second group, the Regulatory Review Working Group (RRWG) is developing guidance on how to gain confidence in safety assessments and safety cases, and on how to conduct regulatory reviews of safety assessments. This paper provides a brief overview of the work being conducted by the Regulatory Review Working Group. (author)

  5. Soil as a Sustainable Resource for the Bioeconomy - BonaRes

    Science.gov (United States)

    Wollschläger, Ute; Amelung, Wulf; Brüggemann, Nicolas; Brunotte, Joachim; Gebbers, Robin; Grosch, Rita; Heinrich, Uwe; Helming, Katharina; Kiese, Ralf; Leinweber, Peter; Reinhold-Hurek, Barbara; Veldkamp, Edzo; Vogel, Hans-Jörg; Winkelmann, Traud

    2017-04-01

    Fertile soils are a fundamental resource for the production of biomass and provision of food and energy. A growing world population and latest climate targets lead to an increasing demand for bio-based products which require preserving and - ideally - improving the long-term productivity of soils as a bio-economic resource. At the same time, other soil functions and ecosystem services need to be maintained: filter for clean water, carbon sequestration, provision and recycling of nutrients, and habitat for biological activity. All these soil functions result from the interaction of a multitude of physical, chemical and biological processes which are insufficiently understood. In addition, we lack understanding about the interplay between the socio-economic system and the soil system and how soil functions benefit human wellbeing, including SDGs. However, a solid and integrated assessment of soil quality requires the consideration of the ensemble of soil functions and its relation to soil management. To make soil management sustainable, we need to establish a scientific knowledge base of complex soil system processes that allows for developing models and tools to quantitatively predict the impact of a multitude of management measures on soil functions. This will finally allow for the provision of options for a site-specific, sustainable soil management. To face this challenge, the German Federal Ministry of Education and Research (BMBF) recently launched the funding program "Soil as a Sustainable Resource for the Bioeconomy - BonaRes". In a joint effort, ten collaborative projects and the coordinating BonaRes Centre are engaged to close existing knowledge gaps for a profound and systemic assessment and understanding of soil functions and their sensitivity to soil management. In BonaRes, the complete process chain of sustainable soil use in the context of a sustainable bio-economy is being addressed: from understanding of soil processes using state-of the art and

  6. Environmental Regulatory Compliance Plan for Site Characterization; Yucca Mountain Site, Nevada Research and Development Area, Nevada: Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-12-01

    The DOE is committed to conduct its operations in an environmentally safe and sound manner, and will comply with applicable environmental statutes and regulations. These objectives are described in DOE Order 5400.1 (Environmental Protection Program Requirements). This document -- the Environmental Regulatory Compliance Plan (ERCP) -- is one method of implementing the policy set forth in DOE Order 5400.1 and the NWPA. The ERCP describes the plan by which the DOE will comply with applicable Federal environmental statutes and regulations. The ERCP also discusses how DOE will address State and local environmental statutes and regulations. 180 refs., 27 figs., 1 tab.

  7. ResStock - Targeting Energy and Cost Savings for U.S. Homes

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Eric J [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-29

    The ResStock analysis tool is helping states, municipalities, utilities, and manufacturers identify which home upgrades save the most energy and money. Across the country there's a vast diversity in the age, size, construction practices, installed equipment, appliances, and resident behavior of the housing stock, not to mention the range of climates. These variations have hindered the accuracy of predicting savings for existing homes. Researchers at the National Renewable Energy Laboratory (NREL) developed ResStock. It's a versatile tool that takes a new approach to large-scale residential energy analysis by combining: large public and private data sources, statistical sampling, detailed subhourly building simulations, high-performance computing. This combination achieves unprecedented granularity and most importantly - accuracy - in modeling the diversity of the single-family housing stock.

  8. Nsite, NsiteH and NsiteM Computer Tools for Studying Tran-scription Regulatory Elements

    KAUST Repository

    Shahmuradov, Ilham

    2015-07-02

    Summary: Gene transcription is mostly conducted through interactions of various transcription factors and their binding sites on DNA (regulatory elements, REs). Today, we are still far from understanding the real regulatory content of promoter regions. Computer methods for identification of REs remain a widely used tool for studying and understanding transcriptional regulation mechanisms. The Nsite, NsiteH and NsiteM programs perform searches for statistically significant (non-random) motifs of known human, animal and plant one-box and composite REs in a single genomic sequence, in a pair of aligned homologous sequences and in a set of functionally related sequences, respectively.

  9. Electricity market models and RES integration: The Greek case

    International Nuclear Information System (INIS)

    Simoglou, Christos K.; Biskas, Pandelis N.; Vagropoulos, Stylianos I.; Bakirtzis, Anastasios G.

    2014-01-01

    This paper presents an extensive analysis of the Greek electricity market for the next 7-year period (2014–2020) based on an hour-by-hour simulation considering five different RES technologies, namely wind, PV, small hydro, biomass and CHP with emphasis on PV integration. The impact of RES penetration on the electricity market operation is evaluated under two different models regarding the organization of the Greek wholesale day-ahead electricity market: a mandatory power pool for year 2014 (current market design) and a power exchange for the period 2015–2020 (Target Model). An integrated software tool is used for the simulation of the current and the future day-ahead market clearing algorithm of the Greek wholesale electricity market. Simulation results indicate the impact of the anticipated large-scale RES integration, in conjunction with each market model, on specific indicators of the Greek electricity market in the long-term. - Highlights: • Analysis of the Greek electricity market for the next 7-year period (2014–2020) based on hour-by-hour simulation. • Five different RES technologies are considered with emphasis on PV integration. • A power pool (for 2014) and a power exchange (for 2015–2020) are considered. • Various market indicators are used for the analysis of the impact of the RES integration on the Greek electricity market. • Two alternative tariff schemes for the compensation of the new ground-mounted PV units from 2015 onwards are investigated

  10. Safety research programs sponsored by Office of Nuclear Regulatory Research. Volume 3. No. 2. Quarterly progress report, April 1-June 30, 1983

    Energy Technology Data Exchange (ETDEWEB)

    Bari, R A; Cerbone, R J; Ginsberg, T; Greene, G A; Guppy, J G; Hall, R E; Luckas, Jr, W J; Reich, M; Saha, P; Sastre, C

    1983-09-01

    The projects reported are the following: HTGR Safety Evaluation, SSC development, Validation and Application, CRBR balance of plant modeling, thermal-hydraulic reactor safety experiments, LWR plant analyzer development, LWR code assessment and application, thermal reactor code development (RAMONA-3B); stress corrosion cracking of PWR steam generator tubing, bolting failure analysis, probability based load combinations for design of category I structures, mechanical piping benchmark problems; human error data for nuclear power plant safety related events, criteria for human engineering regulatory guides and human factors in nuclear power plant safeguards.

  11. Annual report to the Atomic Energy Control Board on the regulatory research and support program April 1, 1995 - March 31, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend activities, undertaken by the Atomic Energy Control Board, beyond what would be possible with in-house resources. The overall objective of the research and support activity is to produce pertinent and independent information that will assist the Board and its staff in making sound, timely and credible decisions for the regulation of nuclear facilities and materials. During Fiscal Year 1995/96, a total of $3,029M was spent on RSP research and support work. The range of activities included projects in the general fields of nuclear reactors, fuel cycle facilities, uranium mines and mills, waste management, dosimetry, health physics, regulations and regulatory process development, and other special support services. Some of this work was organized into sub-program groups. Four sub-programs were launched during the year bringing to twelve the total number. Areas addressed in the sub-programs are environmental impact assessment and management, safety-related computerized systems, seismologic studies, pressure boundary integrity, integrity of containment and safety-related structures, human factors, internal dosimetry, health effects in human populations, physics and fuel studies, probabilistic safety assessment, emergency preparedness, and radiobiology. During the year, there were a total of 118 active projects. This number included projects planned for the year, others which remained incomplete from the previous year and a significant number of projects which were initiated in response to new, high-priority needs. This report presents information on the scope of RSP activities during the year and describes how the program was managed, organized and implemented. Overviews are presented of research and support work undertaken in each field of activity and some highlights of results obtained are included. (Abstract Truncated)

  12. Intricate Resonant Raman Response in Anisotropic ReS2.

    Science.gov (United States)

    McCreary, Amber; Simpson, Jeffrey R; Wang, Yuanxi; Rhodes, Daniel; Fujisawa, Kazunori; Balicas, Luis; Dubey, Madan; Crespi, Vincent H; Terrones, Mauricio; Hight Walker, Angela R

    2017-10-11

    The strong in-plane anisotropy of rhenium disulfide (ReS 2 ) offers an additional physical parameter that can be tuned for advanced applications such as logic circuits, thin-film polarizers, and polarization-sensitive photodetectors. ReS 2 also presents advantages for optoelectronics, as it is both a direct-gap semiconductor for few-layer thicknesses (unlike MoS 2 or WS 2 ) and stable in air (unlike black phosphorus). Raman spectroscopy is one of the most powerful characterization techniques to nondestructively and sensitively probe the fundamental photophysics of a 2D material. Here, we perform a thorough study of the resonant Raman response of the 18 first-order phonons in ReS 2 at various layer thicknesses and crystal orientations. Remarkably, we discover that, as opposed to a general increase in intensity of all of the Raman modes at excitonic transitions, each of the 18 modes behave differently relative to each other as a function of laser excitation, layer thickness, and orientation in a manner that highlights the importance of electron-phonon coupling in ReS 2 . In addition, we correct an unrecognized error in the calculation of the optical interference enhancement of the Raman signal of transition metal dichalcogenides on SiO 2 /Si substrates that has propagated through various reports. For ReS 2 , this correction is critical to properly assessing the resonant Raman behavior. We also implemented a perturbation approach to calculate frequency-dependent Raman intensities based on first-principles and demonstrate that, despite the neglect of excitonic effects, useful trends in the Raman intensities of monolayer and bulk ReS 2 at different laser energies can be accurately captured. Finally, the phonon dispersion calculated from first-principles is used to address the possible origins of unexplained peaks observed in the Raman spectra, such as infrared-active modes, defects, and second-order processes.

  13. CoRes utilization for building PCK in pre-service teacher education on the digestive system topic

    Science.gov (United States)

    Nugraha, Ikmanda

    2017-05-01

    Knowledge of teachers in learning activities in the classroom has a close relationship with how well and how much students learn. Recently, a promising development in teacher education has appeared that centers on the academic construct of pedagogical content knowledge (PCK). This study was an exploratory study into a science teacher education program that seeks to build the foundations on which pre-service teachers can begin to build their pedagogical content knowledge (PCK). The program involved the use of Content Representations (CoRes), which was initially applied as component of a strategy for exploring and gaining insights into the PCK of in-service science teachers. This study involved the researcher and 20 students (third year) in a pre-service teacher education course (School Science I) in science education when the students worked to make content analysis on the digestive system topic. During the course, the students make their own CoRes through a workshop for digestive system topic individually, in pairs and whole class discussion. Data were recorded from students' CoRes, student reflective journals, interviews, and field notes recorded in the researcher's reflective journal. Pre-service teachers' comments from interviews and reflective journals were coded in relation to references about: (1) the effectiveness of variety strategies in building the knowledge bases required to design a CoRes and (2) their awareness and/or development of tentative components of future PCK for a digestive system topic as a result of CoRes construction. Observational data were examined for indications of increasing independence and competency on the part of student teachers when locating appropriate information for designing their CoRes. From this study, it is hoped that the pre-service science teachers are able to build knowledge and then transform it into a form of PCK for digestive system topic for their first classroom planning and teaching to teach digestive system

  14. Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN)

    DEFF Research Database (Denmark)

    Kubiak, Christine; de Andres-Trelles, Fernando; Kuchinke, Wolfgang

    2009-01-01

    in relation to the wide spectrum of clinical research, the European Clinical Research Infrastructures Network (ECRIN) developed a multinational survey in ten European countries. However a lack of common classification framework for major categories of clinical research was identified, and therefore reaching...... with cell therapy, etc.); diagnostic studies; clinical research on nutrition; other interventional clinical research (including trials in complementary and alternative medicine, trials with collection of blood or tissue samples, physiology studies, etc.); and epidemiology studies. Our classification...

  15. Mining Contratação License in the New Regulatory Framework of Brazilian Mining: Some Notes on the Institutes of Research Authorization and Mining Concession

    Directory of Open Access Journals (Sweden)

    Adhemar Ronquim Filho

    2013-06-01

    Full Text Available Given the importance of mining nowadays, Government seeks ways to stimulate its growth, focusing on potentializing research and the advancement of mineral processing, the basic items for speeding up this activity in a profitable way. In this sense, the discussions on the crystallization of a new regulatory framework for the Brazilian mining have been deepened and, despite gathering a significant number of proposals, it does not have a closed text, and, currently, it is far from obtaining an approval or a final word (despite the urgency. However, the analysis of the proposals that have been presented reveals that there is an intention to institute new rules for the modernization of Brazilian mining, and this paper has the purpose of suggesting ways to reconcile conflicts permeated by various dissonant interests that surround the Brazilian mining at this time. It should be emphasized that, given the lack of official disclosure of the amendments proposed, the approach will continue limited to what has been released by MME (Ministry of Mines and Energy and by the studies that have already been presented by experts in the field (connected to government and/or private businesses. It is restricted to discuss changes to be implemented with the new regulatory framework, highlighting points to be observed, and, among the topics that require mandatory update, we can emphasize the changes in the procedures of exploration permits and mining.

  16. Abstracts: HortFlora Res. Spectrum

    OpenAIRE

    Umrao, Dr. V.K.

    2014-01-01

    Overview The HortFlora Research Spectrum (HRS), is an international-peer reviewed, open access journal that serves as a forum for the exchange and dissemination of R & D advances and innovations in all facets of Horticultural Science (Pomology, Olericulture, Floriculture, Post Harvest Technology, Plant Biotechnology, and Medicinal & Aromatic Plants etc.) and its allied branches on an international level. HRS is officially published quarterly (March, June, September and December) every y...

  17. The impact of the privacy rule on cancer research: variations in attitudes and application of regulatory standards.

    Science.gov (United States)

    Goss, Elizabeth; Link, Michael P; Bruinooge, Suanna S; Lawrence, Theodore S; Tepper, Joel E; Runowicz, Carolyn D; Schilsky, Richard L

    2009-08-20

    The American Society of Clinical Oncology (ASCO) Cancer Research Committee designed a qualitative research project to assess the attitudes of cancer researchers and compliance officials regarding compliance with the US Privacy Rule and to identify potential strategies for eliminating perceived or real barriers to achieving compliance. A team of three interviewers asked 27 individuals (13 investigators and 14 compliance officials) from 13 institutions to describe the anticipated approach of their institutions to Privacy Rule compliance in three hypothetical research studies. The interviews revealed that although researchers and compliance officials share the view that patients' cancer diagnoses should enjoy a high level of privacy protection, there are significant tensions between the two groups related to the proper standards for compliance necessary to protect patients. The disagreements are seen most clearly with regard to the appropriate definition of a "future research use" of protected health information in biospecimen and data repositories and the standards for a waiver of authorization for disclosure and use of such data. ASCO believes that disagreements related to compliance and the resulting delays in certain projects and abandonment of others might be eased by additional institutional training programs and consultation on Privacy Rule issues during study design. ASCO also proposes the development of best practices documents to guide 1) creation of data repositories, 2) disclosure and use of data from such repositories, and 3) the design of survivorship and genetics studies.

  18. Reinsalu : Res Publica lisab kiirust / Urmas Reinsalu ; interv. Lauri Tankler

    Index Scriptorium Estoniae

    Reinsalu, Urmas, 1975-

    2004-01-01

    Ilmunud ka: Võta Võim : na russkom jazõke, 28. apr. 2004, lk. 4. Res Publica esikandidaat Urmas Reinsalu erakonna valimiskampaania eesmärkidest, võimalustest nende eesmärkide saavutamiseks ja erakonna valimisprogrammi ning kandidaatide eelistest konkurentide ees

  19. Resúmenes Presentaciones de Pósteres

    Directory of Open Access Journals (Sweden)

    Editor Gabriel Vargas Arana

    2015-12-01

    Full Text Available En este artículo se pueden encontrar los resúmenes de las presentaciones de pósteres del III Congreso Latinoamericano de Plantas Medicinales, desarrollado del 12 al 14 de agosto de 2015 en la ciudad de Iquitos, Perú.

  20. Medical negligence and res ipsa loquitur in South Africa | Patel ...

    African Journals Online (AJOL)

    The inter-relationship between Medicine and Law is most commonly brought to the fore by cases involving medical negligence. This relationship needs to protect all parties concerned based on the probability of reasonableness in terms of who performs the act as well as the patient affected by the act in question. The res ...

  1. Pettumus Res Publicas algas kirikus antud vandest / Margus Tsahkna

    Index Scriptorium Estoniae

    Tsahkna, Margus, 1977-

    2005-01-01

    Autori sõnul on Res Publica petnud inimeste põhiväärtustele tuginevaid ootusi, Eesti riik kaugeneb kodanikust ja tema elulistest huvidest. Isamaaliit paneb ette asuda tegelike probleemide lahendamisele ning kutsub erakondi üles kaitsma rahvuslikke huve

  2. Au Cern, premières collisions de protons hier

    CERN Multimedia

    Galeazzi, Juliette

    2009-01-01

    "Hier, les scientifiques du monde entier ont salué le redémarrage du LHC, grand collisionneur de hadrons, au Cern à Genève. Après quatorze mois d'arrêt, à la suite d'une panne, les expériences ont pris et les premières collisions ont eu lieu" (2 pages)

  3. Overview of the U.S. Nuclear Regulatory Commission collaborative research program to assess tsunami hazard for nuclear power plants on the Atlantic and Gulf Coasts

    Science.gov (United States)

    Kammerer, A.M.; ten Brink, Uri S.; Titov, V.V.

    2017-01-01

    In response to the 2004 Indian Ocean Tsunami, the United States Nuclear Regulatory Commission (US NRC) initiated a long-term research program to improve understanding of tsunami hazard levels for nuclear facilities in the United States. For this effort, the US NRC organized a collaborative research program with the United States Geological Survey (USGS) and the National Oceanic and Atmospheric Administration (NOAA) with a goal of assessing tsunami hazard on the Atlantic and Gulf Coasts of the United States. Necessarily, the US NRC research program includes both seismic- and landslide-based tsunamigenic sources in both the near and the far fields. The inclusion of tsunamigenic landslides, an important category of sources that impact tsunami hazard levels for the Atlantic and Gulf Coasts is a key difference between this program and most other tsunami hazard assessment programs. The initial phase of this work consisted of collection, interpretation, and analysis of available offshore data, with significant effort focused on characterizing offshore near-field landslides and analyzing their tsunamigenic potential and properties. In the next phase of research, additional field investigations will be conducted in key locations of interest and additional analysis will be undertaken. Simultaneously, the MOST tsunami generation and propagation model used by NOAA will first be enhanced to include landslide-based initiation mechanisms and then will be used to investigate the impact of the tsunamigenic sources identified and characterized by the USGS. The potential for probabilistic tsunami hazard assessment will also be explore in the final phases of the program.

  4. Clinical trial regulation in Argentina: overview and analysis of regulatory framework, use of existing tools, and researchers' perspectives to identify potential barriers.

    Science.gov (United States)

    White, Lauren; Ortiz, Zulma; Cuervo, Luis G; Reveiz, Ludovic

    2011-11-01

    To review and analyze the regulatory framework of clinical trial registration, use of existing tools (publicly accessible national/international registration databases), and users' perspectives to identify possible barriers to registration compliance by sponsors and researchers in Argentina. Internationally registered trials recruiting patients in Argentina were found through clincialtrials.gov and the International Clinical Trial Registration Platform (ICTRP) and compared with publically available clinical trials registered through the National Administration of Drugs, Foods, and Medical Devices (ANMAT). A questionnaire addressing hypothesized attitudinal, knowledge-related, idiomatic, technical, economic, and regulatory barriers that could discourage or impede registration of clinical trials was developed, and semi-structured, in-depth interviews were conducted with a purposively selected sample of researchers (investigators, sponsors, and monitors) in Argentina. A response rate of 74.3% (n = 29) was achieved, and 27 interviews were ultimately used for analysis. Results suggested that the high proportion of foreign-sponsored or multinational trials (64.8% of all protocols approved by ANMAT from 1994-2006) may contribute to a communication gap between locally based investigators and foreign-based administrative officials. A lack of knowledge about available international registration tools and limited awareness of the importance of registration were also identified as limiting factors for local investigators and sponsors. To increase compliance and promote clinical trial registration in Argentina, national health authorities, sponsors, and local investigators could take the following steps: implement a grassroots educational campaign to improve clinical trial regulation, support local investigator-sponsor-initiated clinical trials, and/or encourage local and regional scientific journal compliance with standards from the International Committee of Medical Journal

  5. Intervention Research with Youths at Elevated Risk for Suicide: Meeting the Ethical and Regulatory Challenges of Informed Consent and Assent

    Science.gov (United States)

    King, Cheryl A.; Kramer, Anne C.

    2008-01-01

    Intervention research with youths at elevated risk for suicidal behavior and suicide--a vulnerable and high risk population--presents investigators with numerous ethical challenges. This report specifically addresses those challenges involving the informed consent and assent process with parents/guardians and youths. The challenges are delineated…

  6. Annual report to the Atomic Energy Control Board on the regulatory research and support program April 1, 1995 - March 31, 1996

    International Nuclear Information System (INIS)

    1996-10-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend activities, undertaken by the Atomic Energy Control Board, beyond what would be possible with in-house resources. The overall objective of the research and support activity is to produce pertinent and independent information that will assist the Board and its staff in making sound, timely and credible decisions for the regulation of nuclear facilities and materials. During Fiscal Year 1995/96, a total of $3,029M was spent on RSP research and support work. The range of activities included projects in the general fields of nuclear reactors, fuel cycle facilities, uranium mines and mills, waste management, dosimetry, health physics, regulations and regulatory process development, and other special support services. Some of this work was organized into sub-program groups, each of which addresses research and support effort in theme-related areas. Four sub-programs were launched during the year bringing to twelve the total number of such sub-programs. Areas addressed in the sub-programs are environmental impact assessment and management, safety-related computerized systems, seismologic studies, pressure boundary integrity, integrity of containment and safety-related structures, human factors, internal dosimetry, health effects in human populations, physics and fuel studies, probabilistic safety assessment, emergency preparedness, and radiobiology. During the year, there were a total of 118 active projects. This number included projects planned for the year, others which remained incomplete from the previous year and a significant number of projects which were initiated in response to new, high-priority needs. This report presents information on the scope of RSP activities during the year and describes how the program was managed, organized and implemented. Overviews are presented of research and support work undertaken in each field of activity and some highlights of results obtained are

  7. Regulatory Anatomy

    DEFF Research Database (Denmark)

    Hoeyer, Klaus

    2015-01-01

    This article proposes the term “safety logics” to understand attempts within the European Union (EU) to harmonize member state legislation to ensure a safe and stable supply of human biological material for transplants and transfusions. With safety logics, I refer to assemblages of discourses, le...... they arise. In short, I expose the regulatory anatomy of the policy landscape....

  8. Regulatory Governance

    DEFF Research Database (Denmark)

    Kjær, Poul F.; Vetterlein, Antje

    2018-01-01

    Regulatory governance frameworks have become essential building blocks of world society. From supply chains to the regimes surrounding international organizations, extensive governance frameworks have emerged which structure and channel a variety of social exchanges, including economic, political...... by the International Transitional Administrations (ITAs) in Kosovo and Iraq as well as global supply chains and their impact on the garment industry in Bangladesh....

  9. [Bioethical Approach for Nursing Research -Focused on the Use of Research Ethics Committees].

    Science.gov (United States)

    Jeong, Ihn Sook

    2015-06-01

    This paper was written to introduce methods of using the research ethics committee (RES) from requesting the initial review to reporting the close-out for nursing researchers. General ethical principles were described by reviewing the 'Bioethics and Safety Act' and other related guidelines, and constructing some questions and answers. The results were composed of three parts; definition of RES, steps in using RES, and archiving. The 7 steps for using RES were; identifying whether the study needed to be reviewed, by the RES identifying whether the study could be exempted, requesting the initial review after preparing documents, requesting the re-review, requesting an amendment review, requesting a continuing review and reporting the close-out. Nursing researchers need to receive RES approval before starting nursing research involving human subjects. Nursing researchers are urged to use the steps reported in this paper to receive RES approval easily and quickly.

  10. Prediction of regulatory elements

    DEFF Research Database (Denmark)

    Sandelin, Albin

    2008-01-01

    Finding the regulatory mechanisms responsible for gene expression remains one of the most important challenges for biomedical research. A major focus in cellular biology is to find functional transcription factor binding sites (TFBS) responsible for the regulation of a downstream gene. As wet......-lab methods are time consuming and expensive, it is not realistic to identify TFBS for all uncharacterized genes in the genome by purely experimental means. Computational methods aimed at predicting potential regulatory regions can increase the efficiency of wet-lab experiments significantly. Here, methods...

  11. Proceedings of the US Nuclear Regulatory Commission twentieth water reactor safety information meeting; Volume 2, Severe accident research, Thermal hydraulics

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, A.J. [comp.] [Brookhaven National Lab., Upton, NY (United States)

    1993-03-01

    This three-volume report contains papers presented at the Twentieth Water Reactor Safety Information Meeting held at the Bethesda Marriott Hotel, Bethesda, Maryland, during the week of October 21--23, 1992. The papers describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included 10 different papers presented by researchersfrom CEC, China, Finland, France, Germany, Japan, Spain and Taiwan. Selected papers have been processed separately for inclusion in the Energy Science and Technology Database.

  12. Nuclear regulatory decision making

    International Nuclear Information System (INIS)

    Wieland, Patricia; Almeida, Ivan Pedro Salati de

    2011-01-01

    The scientific considerations upon which the nuclear regulations are based provide objective criteria for decisions on nuclear safety matters. However, the decisions that a regulatory agency takes go far beyond granting or not an operating license based on assessment of compliance. It may involve decisions about hiring experts or research, appeals, responses to other government agencies, international agreements, etc.. In all cases, top management of the regulatory agency should hear and decide the best balance between the benefits of regulatory action and undue risks and other associated impacts that may arise, including issues of credibility and reputation. The establishment of a decision framework based on well established principles and criteria ensures performance stability and consistency, preventing individual subjectivity. This article analyzes the challenges to the decision-making by regulatory agencies to ensure coherence and consistency in decisions, even in situations where there is uncertainty, lack of reliable information and even divergence of opinions among experts. The article explores the basic elements for a framework for regulatory decision-making. (author)

  13. Res Publica tähistab sünnipäeva konverentsiga / Lauri Tankler

    Index Scriptorium Estoniae

    Tankler, Lauri

    2003-01-01

    Ilmunud ka: Võta Võim : na russkom jazõke 3. dets. lk. 3. Res Publica saab 2-aastaseks, mille puhul korraldatakse konverents "Riik ja Res Publica". Vt. samas: Selle aasta veebruaris said kuldmärgid

  14. Res Publica kärbiks võimuorganite koosseise / Argo Ideon

    Index Scriptorium Estoniae

    Ideon, Argo, 1966-

    2002-01-01

    Res Publica taotleb Riigikogu kärpimist 61 liikmeni, lubab kahandada kohalike volikogude koosseise, Tallinna abilinnapeade arvu ja kaotada portfellita ministrite kohad. Vt. samas: Res Publica valimisnimekiri Tallinnas

  15. Res Publica asus Reformierakonda Tallinna võimuliidust tõrjuma / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2005-01-01

    Res Publica Tallinna piirkonna juhatuse liikme Siim Roode sõnul teeb Res Publica Keskerakonna Tallinna piirkonna juhatusele ettepaneku koalitsiooniläbirääkimiste alustamiseks. Lisa: Paltsu ettekäändeks Unicom

  16. Res Publica hakkab kaaluma Kohtla-Järve võimuliidust lahkumist / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje 19. nov. lk. 1. Res Publica eestseisuse ettepanek Kohtla-Järve osakonnale lahkuda koalitsioonist. Osakonna juhatuse otsus esitada Hants Hint volikogu esimehe kandidaadiks. Res Publica liikmete käitumise arutelu aukohtus

  17. Res Publica presidendikandidaatide nimed selguvad neljapäevaks / Rauno Veri, Urmo Kübar

    Index Scriptorium Estoniae

    Veri, Rauno, 1978-

    2006-01-01

    Res Publica, Isamaaliit, Reformierakond, SDE ja Keskerakond otsivad ühist presidendikandidaati, ainsa parlamendierakonnana ei osale läbirääkimistel Rahvaliit. Reformierakonna, SDE presidendikandidaatidest; Res Publica naiskogu ja Väärikate Kogu ühisavaldusest

  18. Sisetülides Res Publica heitis liidu Keskerakonnaga kõrvale / Urmas Seaver

    Index Scriptorium Estoniae

    Seaver, Urmas, 1973-

    2005-01-01

    Res Publica juhatus otsustas toetada senise koalitsiooni jätkamist Tallinnas. Res Publica ja Reformierakonna täiendatud koalitsioonileppest. Reformierakonna Tallinna piirkonna juhi Keit Pentuse hinnang võimutülile. Lisa: Võimuleppe lisa

  19. Res Publica : umbusaldamine võib lõpetada senise koalitsiooni / Villy Paimets

    Index Scriptorium Estoniae

    Paimets, Villy, 1972-

    2005-01-01

    Res Publica erakorraline volikogu avaldas toetust justiitsministrile ja andis peaministrile volitused lõpetada justiitsministri umbusaldamise korral senine koalitsioon ning alustada läbirääkimisi Isamaaliiduga. Lisa: Res Publica toetab Vaherit

  20. Res Publica andis kolmele poliitikule fiktiivse elukoha / Kärt Karpa

    Index Scriptorium Estoniae

    Karpa, Kärt, 1973-

    2002-01-01

    Väidetavalt lasi Res Publica enne kohalikke valimisi ühte Pirita eramajja sisse registreerida Jaanus Rahumäe ja veel kaks Res Publica liiget, et nad saaksid kandideerida Tallinna volikogusse ja Pirita halduskogusse

  1. Riigikogu aseesimeeste valimine tekitas paksu verd : Res Publical riigikogu juhatuses kaks kohta / Katrin Pauts

    Index Scriptorium Estoniae

    Pauts, Katrin, 1977-

    2005-01-01

    Riigikogu aseesimeesteks valiti Res Publica liige Taavi Veskimägi ja Keskerakonna liige Toomas Varek. Opositsiooniparteil Res Publica on nüüd juhatuses kaks kohta. Erakondade juhtpoliitikute kommentaare

  2. RES scintigraphy in polycythemia vera and secondary or relative polycythemia

    Energy Technology Data Exchange (ETDEWEB)

    Rudberg, U. (Depts. of Diagnostic Radiology and Internal Medicine, St. Goeran' s Hospital, Stockholm (Sweden)); Skaarberg, K.O. (Depts. of Diagnostic Radiology and Internal Medicine, St. Goeran' s Hospital, Stockholm (Sweden))

    1993-03-01

    Scintigraphy of the reticuloendothelial system (RES) was performed in 19 patients with polycythemia vera (PCV) and in 18 with secondary or relative polycythemia (PS). Bone marrow extension was found in all patients with PCV and in 11 of 18 patients with PS. The patients with PCV had a higher degree of extension than those with PS. Increased pelvic bone marrow activity was found in 16 of 19 PCV patients, but in none with PS. Splenomegaly was found in 9 patients with PCV, and in none with PS. It is concluded that RES scintigraphy in the majority of patients may differentiate between PCV and PS using the parameters pelvic bone marrow activity, bone marrow extension and splenic size. (orig.).

  3. RES scintigraphy in polycythemia vera and secondary or relative polycythemia

    International Nuclear Information System (INIS)

    Rudberg, U.; Skaarberg, K.O.

    1993-01-01

    Scintigraphy of the reticuloendothelial system (RES) was performed in 19 patients with polycythemia vera (PCV) and in 18 with secondary or relative polycythemia (PS). Bone marrow extension was found in all patients with PCV and in 11 of 18 patients with PS. The patients with PCV had a higher degree of extension than those with PS. Increased pelvic bone marrow activity was found in 16 of 19 PCV patients, but in none with PS. Splenomegaly was found in 9 patients with PCV, and in none with PS. It is concluded that RES scintigraphy in the majority of patients may differentiate between PCV and PS using the parameters pelvic bone marrow activity, bone marrow extension and splenic size. (orig.)

  4. Annual report to the Atomic Energy Control Board on the Regulatory Research and Support Program April 1, 1994 - March 31, 1995

    International Nuclear Information System (INIS)

    1996-03-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend activities, undertaken by the Atomic Energy Control Board, beyond what would be possible with in-house resources. The overall objective of the research and support activity is to produce pertinent and independent information that will assist the Board and its staff in making sound, timely and credible decisions for the regulation of nuclear facilities and materials. Represented in this report is a cataloging of seven appendices. The membership of active review panels is given in Appendix A. Appendix B contains summary descriptions and information on the status of individual projects. Appendix C presents a list of those projects which were within the overall RSP but were not active during the year. Appendix D lists the projects undergoing review of final report or post-project evaluation. All projects which were worked on during the year are listed in Appendix E. Specific objectives set for the RSP for Fiscal Year 1994/95 and the degree to which the objectives were achieved are outlined in Appendix F. Appendix G lists the INFO-series reports that were published during Fiscal Year 1994/95. 157 tabs

  5. Annual report to the Atomic Energy Control Board on the Regulatory Research and Support Program April 1, 1994 - March 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The Regulatory Research and Support Program (RSP) is intended to augment and extend activities, undertaken by the Atomic Energy Control Board, beyond what would be possible with in-house resources. The overall objective of the research and support activity is to produce pertinent and independent information that will assist the Board and its staff in making sound, timely and credible decisions for the regulation of nuclear facilities and materials. Represented in this report is a cataloging of seven appendices. The membership of active review panels is given in Appendix A. Appendix B contains summary descriptions and information on the status of individual projects. Appendix C presents a list of those projects which were within the overall RSP but were not active during the year. Appendix D lists the projects undergoing review of final report or post-project evaluation. All projects which were worked on during the year are listed in Appendix E. Specific objectives set for the RSP for Fiscal Year 1994/95 and the degree to which the objectives were achieved are outlined in Appendix F. Appendix G lists the INFO-series reports that were published during Fiscal Year 1994/95. 157 tabs.

  6. Further developments of the RES3T sorption database

    International Nuclear Information System (INIS)

    Brendler, V.

    2002-01-01

    RES 3 T - the Rossendorf expert system for surface and sorption thermodynamics currently under development has been expanded towards the provision of comprehensive sorption data sets suitable for complex natural systems of rocks and soils. Also a statistical evaluation of the available SCM (surface complexation model) data is now implemented. Finally, a normalization of SCM parameters to a standard site density has been incorporated. (orig.)

  7. Regulatory research of the PWR severe accident information needs and instrumentation availability for hydrogen control and management

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jae-Hong; Park, Gun-Chul; Suh, Kune Y.; Kang, Yun-Moon; Lee, Un-Jang; Oh, Se-Chul; Lee, Jin-Yong [Seoul Nationl Univ., Seoul (Korea, Republic of)

    1998-03-15

    During the current research period, we have set forth the methodology for identification of a severe accident, developed a framework for hydrogen management decision trees, and analyzed the literature on hydrogen management and experimental data for hydrogen bum. Specifically, we have summarized me results for information needs in a severe accident obtained in the U.S. and other countries, and applied the methodology to the reference plant YGN 3 and 4 as part of severe accident management. We have also examined the existing instruments in terms of their availability and survivability during a severe accident, and identified additionally needed information needs and instruments. We have identified dominant accident sequences for me reference plant YGN 3 and 4 to construct decision trees, and extracted available data from the IPE study of the plant. Based upon the data we have performed preliminary study on the decision tree and decision node. Last, we have examined various mechanisms for hydrogen generation and reIevant experimental data to predict me amount of hydrogen generation and governing factors in me process. We have also reviewed the hydrogen generation related models in the severe accident analysis.

  8. Res Publica pakub sponsoritele anonüümsust / Virkko Lepassalu

    Index Scriptorium Estoniae

    Lepassalu, Virkko, 1971-

    2003-01-01

    Mõnede tõenäoliselt Res Publica lähedaste ettevõtjate seas levib erakonna nimel rahapalumiskiri, mis lubab sponsorile anonüümsust. Vt. samas: Telefonikõne ettevõtja ja Res Publica aseesimehe Ken-Marti Vaheri vahel ; Teisedki on saanud rahaallikaid varjates ; Res Publica on loobunud reklaamibroneeringutest

  9. Res Publica aukohus heidab juhtidele ette eetikavääratust / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2002-01-01

    Ilmunud ka: Põhjarannik ; Severnoje Poberezhje 22. november lk. 3;4. Res Publica aukohus arvab, et Res Publica juhid on rikkunud erakonna põhikirja, sisekorda ja eetikakoodeksit Kohtla-Järve juhtumi lahendamisel. Kohtla-Järvel sai linnapeaks riisumiskahtlusega uurimise all olev Valeri Korb tänu Keskerakonna ja Res Publica koalitsioonileppele. Kommenteerib Juhan Kivirähk

  10. Res Publica toetus pole aastaga üle viie protsendi tõusnud / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2006-01-01

    Emori jaanuarikuu küsitluse põhjal on 22 protsendiga suurim toetajaskond Keskerakonnal, Res Publica reiting on aasta aega püsinud viie ja kolme toetusprotsendi vahel. Vt. samas: Taavi Veskimägi. 2 küsimust. Diagrammid: Res Publica valiks riigikogusse tagasi vaid kolm protsenti valijaist; Toetus Res Publicale

  11. Res Publica ladvikus hõõgub võimutüli / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2006-01-01

    22. aprillil kogunenud Res Publica volikogu toetas 60 poolthäälega ühe vastu Res Publica ja Isamaaliidu ühinemist. Tõnis Palts teatas volikogul esinedes, et Taavi Veskimägi ei sobi Res Publica poolseks läbirääkimiste juhiks

  12. Res Publicas käärib mäss / Hants Hint

    Index Scriptorium Estoniae

    Hint, Hants

    2002-01-01

    Res Publica eestseisuse liige ja Ida-Viru piirkonna esimees Hants Hint vastab küsimustele Res Publica ja Keskerakonna võimuliidu moodustamisega tekkinud skandaali, Res Publica esimehe Juhan Partsiga kohtumise kohta. Vt. samas: "Korbi toetajaid ootab hukkamõist"

  13. Nuclear energy research initiative, an overview of the cooperative program for the risk-informed assessment of regulatory and design requirements for future nuclear power plants

    International Nuclear Information System (INIS)

    Ritterbusch, Stanley E.

    2000-01-01

    EPRI sstudies have shown that nuclear plant capital costs will have to decrease by about 35% to 40% to be competitive with fossil-generated electricity in the Unite States. Also, the ''first concrete'' to fuel load construction schedule will have to be decreased to less than 40 months. Therefore, the U. S. Department of Energy (DOE) initiate the Nuclear Energy Research Initiative (NERI) and ABB CENP proposed a cooperative program with Sandia National Laboratory (SNL) and Duke Engineering and Services (DE and S) to begin an innovative research effort to drastically cut the cost of new nuclear power plant construction for the U. S. de-regulated market place. This program was approved by the DOE through three separate but coordinated ''cooperative agreements.'' They are the ''Risk-Informed Assessment of Regulatory and Design Requirements for Future Nuclear Power Plants'' (Risk-Informed NPP), the ''Smart Nuclear Power Plant Program'' (Smart-NPP), and ''Design, Procure, Construct, Install and Test'' (DPCIT) Program. DOE funded the three cooperative agreements at a level of $2.6 million for the first year of the program. Funding for the complete program is durrently at a level $6.9 million, however, ABB CENP and all partners anticipate that the scope of the NERI program will be increased as a result of the overall importance of NERI to the U. S. Government. The Risk-Informed NPP program, which is aimed at revising costly regularory and design requirements without reducing overall plant safety, has two basic tasks: ''development of Risk-Informed Methods'' and ''strengthening the Reliability Database.'' The overall objective of the first task is to develop a scientific, risk-informed approach for identifying and simplifying deterministic industry standards, regulatory requirements, and safety systems that do not significantly contribute to nuclear power plant reliability and safety. The second basic task is to develop a means for strengthening the reliability database

  14. Regulatory Control of Radiation Sources. Safety Guide

    International Nuclear Information System (INIS)

    2009-01-01

    This Safety Guide is intended to assist States in implementing the requirements established in Safety Standards Series No. GS-R-1, Legal and Governmental Infrastructure for Nuclear, Radiation, Radioactive Waste and Transport Safety, for a national regulatory infrastructure to regulate any practice involving radiation sources in medicine, industry, research, agriculture and education. The Safety Guide provides advice on the legislative basis for establishing regulatory bodies, including the effective independence of the regulatory body. It also provides guidance on implementing the functions and activities of regulatory bodies: the development of regulations and guides on radiation safety; implementation of a system for notification and authorization; carrying out regulatory inspections; taking necessary enforcement actions; and investigating accidents and circumstances potentially giving rise to accidents. The various aspects relating to the regulatory control of consumer products are explained, including justification, optimization of exposure, safety assessment and authorization. Guidance is also provided on the organization and staffing of regulatory bodies. Contents: 1. Introduction; 2. Legal framework for a regulatory infrastructure; 3. Principal functions and activities of the regulatory body; 4. Regulatory control of the supply of consumer products; 5. Functions of the regulatory body shared with other governmental agencies; 6. Organization and staffing of the regulatory body; 7. Documentation of the functions and activities of the regulatory body; 8. Support services; 9. Quality management for the regulatory system.

  15. The progress of RES environment in the most recent member states of the EU

    Energy Technology Data Exchange (ETDEWEB)

    Patlitzianas, Konstantinos [Management and Decision Support Systems Lab (EPU-NTUA), School of Electrical and Computer Engineering, National Technical University of Athens, 9, Iroon Polytechniou str., 15773, Athens (Greece); Karagounis, Konstantinos [National and Kapodistrian University of Athens, Dental School, 2 Thivon Str., Goudi, 11527 Athens (Greece)

    2011-02-15

    The most recent EU member states seem to have important Renewable Energy Sources (RES) potential. However, they have serious structural difficulties in development and integration of RES policies. Indeed, the balanced development of RES between the member states is urgent today. The penetration of the RES in these member states is related to the existence of an appropriate environment (political, economical, social, and technological). The current paper is based on an analytical review and specific PEST analysis aiming to assess the current RES environment and the progress so far in each of these most recent EU members. (author)

  16. [Advances in research on regulatory effects of chemical ingredients of traditional Chinese medicine on UDP-glucuronosyltransferase 1A1 expression and activity].

    Science.gov (United States)

    Xin, Hong; Xu, Wei

    2017-02-01

    Uridine 5'-diphosphate-glucuronosyltransferase1A1(UGT1A1) is a major phase Ⅱ metabolism enzyme, responsible for glucuronidation and elimination of drugs and endogenous compounds, playing a vital role in sustaining endogenous metabolism balance. Therefore, changes in UGT1A1 expression/functional can not only cause adverse clinical drug/herbs-drug interactions, but also lead to metabolic disorder of endogenous substances, causing high blood bilirubin, bilirubin encephalopathy and liver injury, as well as other side effects. To date, many studies have found that a variety of clinical medicines and medicinal ingredients can regulate UGT1A1 activity. This article would summarize the advances in research on drug metabolism and toxicology in domestic and foreign literature, and investigate the regulatory effects of different types of traditional Chinese medicine(TCM) ingredients(such as flavonoids, coumarins, alkaloids) on UGT1A1 expression and activity, including inhibitory effect of TCM chemical ingredients on UGT1A1 and effect of TCM chemical ingredients on UGT1A1. It is hoped that this review could provide depth understanding and certain reference for the interaction between chemical ingredients of TCM and UGT1A1, which is of great significance to guide the rational clinical use in future. Copyright© by the Chinese Pharmaceutical Association.

  17. Anti-regulatory T cells

    DEFF Research Database (Denmark)

    Andersen, Mads Hald

    2017-01-01

    responses to tumours or inhibiting autoimmunity development. However, recent studies report the discovery of self-reactive pro-inflammatory T cells—termed anti-regulatory T cells (anti-Tregs)—that target immune-suppressive cells. Thus, regulatory cells can now be defined as both cells that suppress immune...... reactions as well as effector cells that counteract the effects of suppressor cells and support immune reactions. Self-reactive anti-Tregs have been described that specifically recognize human leukocyte antigen-restricted epitopes derived from proteins that are normally expressed by regulatory immune cells......Our initial understanding of immune-regulatory cells was based on the discovery of suppressor cells that assure peripheral T-cell tolerance and promote immune homeostasis. Research has particularly focused on the importance of regulatory T cells (Tregs) for immune modulation, e.g. directing host...

  18. Research

    African Journals Online (AJOL)

    abp

    9 juil. 2015 ... stratégique de la gestion des ressources hospitalières. Hermès ... soins et les décideurs politiques s'aperçoivent que les objectifs du millénium pour le ..... un mauvais recrutement des syndicalistes, la faible collaboration du.

  19. Tesis doctorales 2012-2013 : Serie resúmenes

    OpenAIRE

    Di Gregori, María Cristina

    2014-01-01

    En continuidad con la publicación de Serie Resúmenes, Tesis Doctorales, la Universidad Nacional de La Plata presenta un nuevo libro que contiene información sobre las tesis defendidas y aprobadas correspondiente a los doctores titulados en el período 2012-2013. Como señalarámos en nuestro volumen inaugural, esta publicación se inscribe en el marco de la revalorización que sostiene nuestra institución respecto del valor de la comunicación y difusión del conocimiento; en este caso, la producció...

  20. Resúmenes de los trabajos sobre las Enfermedades Neuromusculares

    OpenAIRE

    Congreso Nacional de Neurología

    2010-01-01

    Las enfermedades neuromusculares constituyen un conjunto de afectaciones que afectan las neuronas motoras periférica, las vías motoras eferentes o los efectores (músculos esqueléticos). Sus manifestaciones clínicas son muy variadas y dependen de la causa y de los niveles de afectación. En este acápite se pueden encontrar los resúmenes de trabajos relacionados con el síndrome de Guillain Barre, polineuropatía diabética, Atrofia Muscular Espinal, Distrofia miotónica y otros todos presentados en...

  1. Regulatory Physiology

    Science.gov (United States)

    Lane, Helen W.; Whitson, Peggy A.; Putcha, Lakshmi; Baker, Ellen; Smith, Scott M.; Stewart, Karen; Gretebeck, Randall; Nimmagudda, R. R.; Schoeller, Dale A.; Davis-Street, Janis

    1999-01-01

    As noted elsewhere in this report, a central goal of the Extended Duration Orbiter Medical Project (EDOMP) was to ensure that cardiovascular and muscle function were adequate to perform an emergency egress after 16 days of spaceflight. The goals of the Regulatory Physiology component of the EDOMP were to identify and subsequently ameliorate those biochemical and nutritional factors that deplete physiological reserves or increase risk for disease, and to facilitate the development of effective muscle, exercise, and cardiovascular countermeasures. The component investigations designed to meet these goals focused on biochemical and physiological aspects of nutrition and metabolism, the risk of renal (kidney) stone formation, gastrointestinal function, and sleep in space. Investigations involved both ground-based protocols to validate proposed methods and flight studies to test those methods. Two hardware tests were also completed.

  2. Regulatory Benchmarking

    DEFF Research Database (Denmark)

    Agrell, Per J.; Bogetoft, Peter

    2017-01-01

    Benchmarking methods, and in particular Data Envelopment Analysis (DEA), have become well-established and informative tools for economic regulation. DEA is now routinely used by European regulators to set reasonable revenue caps for energy transmission and distribution system operators. The appli......Benchmarking methods, and in particular Data Envelopment Analysis (DEA), have become well-established and informative tools for economic regulation. DEA is now routinely used by European regulators to set reasonable revenue caps for energy transmission and distribution system operators....... The application of bench-marking in regulation, however, requires specific steps in terms of data validation, model specification and outlier detection that are not systematically documented in open publications, leading to discussions about regulatory stability and economic feasibility of these techniques...

  3. Regulatory Benchmarking

    DEFF Research Database (Denmark)

    Agrell, Per J.; Bogetoft, Peter

    2017-01-01

    Benchmarking methods, and in particular Data Envelopment Analysis (DEA), have become well-established and informative tools for economic regulation. DEA is now routinely used by European regulators to set reasonable revenue caps for energy transmission and distribution system operators. The appli......Benchmarking methods, and in particular Data Envelopment Analysis (DEA), have become well-established and informative tools for economic regulation. DEA is now routinely used by European regulators to set reasonable revenue caps for energy transmission and distribution system operators....... The application of benchmarking in regulation, however, requires specific steps in terms of data validation, model specification and outlier detection that are not systematically documented in open publications, leading to discussions about regulatory stability and economic feasibility of these techniques...

  4. Reactors licensing: proposal of an integrated quality and environment regulatory structure for nuclear research reactors in Brazil; Licenciamento de reatores: proposta de uma estrutura regulatoria integrada com abordagem em qualidade e meio ambiente para reatores de pesquisa no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Serra, Reynaldo Cavalcanti

    2014-07-01

    A new integrated regulatory structure based on quality and integrated issues has been proposed to be implemented on the licensing process of nuclear research reactors in Brazil. The study starts with a literature review about the licensing process in several countries, all of them members of the International Atomic Energy Agency. After this phase it is performed a comparative study with the Brazilian licensing process to identify good practices (positive aspects), the gaps on it and to propose an approach of an integrated quality and environmental management system, in order to contribute with a new licensing process scheme in Brazil. The literature review considered the following research nuclear reactors: Jules-Horowitz and OSIRIS (France), Hanaro (Korea), Maples 1 and 2 (Canada), OPAL (Australia), Pallas (Holand), ETRR-2 (Egypt) and IEA-R1 (Brazil). The current nuclear research reactors licensing process in Brazil is conducted by two regulatory bodies: the Brazilian National Nuclear Energy Commission (CNEN) and the Brazilian Institute of Environment and Renewable Natural Resources (IBAMA). CNEN is responsible by nuclear issues, while IBAMA by environmental one. To support the study it was applied a questionnaire and interviews based on the current regulatory structure to four nuclear research reactors in Brazil. Nowadays, the nuclear research reactor’s licensing process, in Brazil, has six phases and the environmental licensing process has three phases. A correlation study among these phases leads to a proposal of a new quality and environmental integrated licensing structure with four harmonized phases, hence reducing potential delays in this process. (author)

  5. Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

    OpenAIRE

    Chen, Yvonne Y.; Jensen, Michael C.; Smolke, Christina D.

    2010-01-01

    RNA molecules perform diverse regulatory functions in natural biological systems, and numerous synthetic RNA-based control devices that integrate sensing and gene-regulatory functions have been demonstrated, predominantly in bacteria and yeast. Despite potential advantages of RNA-based genetic control strategies in clinical applications, there has been limited success in extending engineered RNA devices to mammalian gene-expression control and no example of their application to functional res...

  6. Écuyères and "doing gender"

    DEFF Research Database (Denmark)

    Hedenborg, Susanna; Pfister, Gertrud Ursula

    2012-01-01

    masculinity and horsemanship conveys the impression that women had nothing to do with horses. This is true for many situations. The circus arena, however, seems to have been an exception as women could perform there. At the heart of the performances was not only equestrianism, but also the notion of gender......The purpose of this article is to analyse gender relations in equestrianism from the beginning of the 19th to the first decades of the 20th century. Focus will be on the female horse riding circus artists, the écuyères. The fact that women were circus riders at this time is interesting as in many....... It is even likely that ”doing gender” was an indispensable part of the show, as the allure of the écuyères depended on the embodiment and presentation of seemingly incompatible features: beauty, grace and femininity as well as mastery of an art that was a traditionally male domain....

  7. Nuclear regulatory developments in Canada

    International Nuclear Information System (INIS)

    Binder, M.

    2012-01-01

    This paper from CNSC discusses nuclear regulatory developments in Canada. It starts with the Fukushima accident and the effect on the nuclear sector. It summarises what CNSC has done, what it has learned and their plans going forward. It has made recommendations to IAEA for international enhancements to regulatory procedures. It outline the activities of Canada's nuclear power plants, Canada's uranium projects, deep geological repository and waste management as well as nuclear research in Canada.

  8. 76 FR 28102 - Notice of Issuance of Regulatory Guide

    Science.gov (United States)

    2011-05-13

    ..., Probabilistic Risk Assessment Branch, Division of Risk Analysis, Office of Nuclear Regulatory Research, U.S... results of risk analyses are used to help justify regulatory action. As such, the principles, process, and... NUCLEAR REGULATORY COMMISSION [NRC-2009-0385] Notice of Issuance of Regulatory Guide AGENCY...

  9. Joint US Geological Survey, US Nuclear Regulatory Commission workshop on research related to low-level radioactive waste disposal, May 4-6, 1993, National Center, Reston, Virginia; Proceedings

    Science.gov (United States)

    Stevens, Peter R.; Nicholson, Thomas J.

    1996-01-01

    This report contains papers presented at the "Joint U.S. Geological Survey (USGS) and U.S. Nuclear Regulatory Commission (NRC) Technical Workshop on Research Related to Low-Level Radioactive Waste (LLW) Disposal" that was held at the USGS National Center Auditorium, Reston, Virginia, May 4-6, 1993. The objective of the workshop was to provide a forum for exchange of information, ideas, and technology in the geosciences dealing with LLW disposal. This workshop was the first joint activity under the Memorandum of Understanding between the USGS and NRC's Office of Nuclear Regulatory Research signed in April 1992.Participants included invited speakers from the USGS, NRC technical contractors (U.S. Department of Energy (DOE) National Laboratories and universities) and NRC staff for presentation of research study results related to LLW disposal. Also in attendance were scientists from the DOE, DOE National Laboratories, the U.S. Environmental Protection Agency, State developmental and regulatory agencies involved in LLW disposal facility siting and licensing, Atomic Energy Canada Limited (AECL), private industry, Agricultural Research Service, universities, USGS and NRC.

  10. The impact of ISO 9001:2008 quality management system implementation on organizational performance of the Nuclear Regulatory Division of Philippine Nuclear Research Institute

    International Nuclear Information System (INIS)

    Borras, Alan M.

    2012-02-01

    This report aims to determine the perception of Nuclear Regulatory Division staff of the Phiippine Nuclear Research Institute on the implementation of ISO 9001-2008 Quality Management System in terms of the eight quality management principles, its effect to their process performance and its impact to NRD organizational performance. Likewise, it aims to determine if there are direct relationshops between the ISO-QMS implementation, the process performance, and organizational performance in terms of customers' satisfaction. Two survey instruments were used for quantitative data collection from two groups of respondents, i.e., the NRD staff for their perception and as internal customers and the licenses (holder of valid radioactive material license) as the external customers. All items were measured on a 4-point Likert Scale ranging from 1 as Strongly Disagree/Strongly Dissatisfied to 4 Strongly Agree/Strongly Satisfied. The data were analyzed statistically by means of Microsoft Ofice Excel and Statistical Analysis Software (SAS). Linear regression was used to test the hypotheses. The results show that the perception of the NRD staff are agreeable with the implementation of the ISO 9001:2008 in their organization which indicated 'customer focused' and 'process approach' as the strength of the practices while 'leadership' and 'mutually beneficial supplier relationship' as the weakest. Data on NRD staff perceptions of ISO 9001:2008 also show that QMS implementation has improved the effectiveness and efficiency of their core business processes which impacted on the organizational performance. The external customers rated 'competence', 'courtesy' and 'credibility' as the three highest attributes of NRD service quality which denote their full trust and confidence to NRD as a nuclear regulatory body. Meanwhile, the same external customers rated 'tangibles', 'reliability' and 'access' as the lowest attributes. Furthermore, the results also show a significant and strong

  11. Research

    African Journals Online (AJOL)

    ebutamanya

    9 juin 2015 ... &Corresponding author: Manel Limam, Département de Médecine ... Key words: Partogramm, évaluation, audit clinique, obstétrique ... critères portant sur la naissance et la surveillance immédiate qui ... de trois quarts de la mortalité maternelle entre 2000 et 2015 et la .... l'anesthésie générale (60%).

  12. Research

    African Journals Online (AJOL)

    raoul

    8 mars 2012 ... SA sont souvent plus sévères que celles à SCN. Elles peuvent entraîner des complications abdominales et conduire à un retrait anticipé du cathéter ainsi qu'à un passage plus rapide en hémodialyse. Une péritonite polymicrobienne est survenue dans 10.7% des cas. Ce chiffre rejoint celui de e Szeto et al ...

  13. Research

    African Journals Online (AJOL)

    abp

    10 mars 2016 ... Introduction: Les grossesses gémellaires sont associées à un risque de morbimortalité périnatale plus élevé que les grossesses simples. ... étaient plus à risque en exposant notamment à l'hypotrophie chez les nouveau-nés à terme. ... Les critères d'inclusion des patients se sont basés sur la définition.

  14. Strengthening Regulatory Competence in Pakistan

    International Nuclear Information System (INIS)

    Sadiq, M.

    2016-01-01

    Capacity building of Pakistan Nuclear Regulatory Authority is considered an essential element in pursuit of its vision to become a world class regulatory body. Since its inception in 2001, PNRA has continuously endeavoured to invest in its people, develop training infrastructure and impart sound knowledge and professional skills with the aim to improve its regulatory effectiveness. The use of nuclear and radioactive material in Pakistan has increased manifold in recent years, thus induction of more manpower was needed for regulatory oversight. PNRA adopted two pronged approach for meeting the manpower demand (a) employment of university graduates through fast track recruitment drive and (b) induction of graduates by offering fellowships for Master degree programs. Although, the newly employed staff was selected on the basis of their excellent academic qualifications in basic and applied sciences, but they required rigorous knowledge and skills in regulatory perspectives. In order to implement a structured training program, PNRA conducted Training Needs Assessment (TNA) and identified competency gaps of the regulatory staff in legal, technical, regulatory practice and behavioural domains. PNRA took several initiatives for capacity building which included establishment of a training centre for sustainability of trainings, initiation of a fellowship scheme for Master program, attachment of staff at local institutes for on-the-job training and placement at foreign regulatory bodies and organizations for technical development with the assistance of IAEA. The above strategies have been very beneficial in competence building of the PNRA staff to perform all regulatory activities indigenously for nuclear power plants, research reactors and radiation facilities. Provision of vibrant technical support to IAEA and Member States in various programs by PNRA is a landmark of these competence development efforts. This paper summarizes PNRA initiatives and the International Atomic

  15. In media res: commenting on the trajectory of lives.

    Science.gov (United States)

    Bishop, Jeffery; Barina, Rachelle; Stahl, Devan

    2013-01-01

    The stories in this issue of Narrative Inquiry in Bioethics demonstrate two important things. First these stories explore the space between bodily impairment and the social structures that both enable and constrain the flourishing of those who are differently embodied. The authors of these narratives resist the dominant biomedical interpretation of their impairments, but also demonstrate their dependency upon others--social, medical, or familial others. Second, in writing these narratives, the authors are also engaged in an act of identity formation, which sometimes challenge and sometimes embrace the label of disability. By telling their stories in the middle of the action of their lives--in media res, taking up or resisting the label of disability-they also demonstrate the way in which lives can be lived open to new possibilities and interpretations.

  16. Regulatory aspects of radiopharmaceuticals

    International Nuclear Information System (INIS)

    Kristensen, K.

    1985-01-01

    Regulatory systems in the field of radiopharmaceuticals have two main purposes: efficacy and safety. Efficacy expresses the quality of the diagnostic and therapeutic process for the patient. Safety involves the patient, the staff, and the environment. The world situation regarding regulations for radiopharmaceuticals is reviewed on the basis of a survey in WHO Member States. The main content of such regulations is discussed. The special properties of radiopharmaceuticals compared with ordinary drugs may call for modified regulations. Several countries are preparing such regulations. Close co-operation and good understanding among scientists working in hospital research, industry and regulatory bodies will be of great importance for the fast and safe introduction of new radiopharmaceuticals for the benefit of the patient. Before introducing new legislation in this field, a radiopharmaceutical expert should analyse the situation in the country and the relationship to the existing regulations. It is expected that the most important factor in promoting the fast introduction of new, safe and effective radiopharmaceuticals will be the training of people working within the regulatory bodies. It is foreseen that the IAEA and WHO will have an important role to play by providing expert advice and training in this area. (author)

  17. Regulatory foci and the big five

    OpenAIRE

    Bak, Waclaw

    2009-01-01

    The distinction between promotion and prevention focus (Higgins, 1997) have been employed by many researchers dealing with processes of self-regulation. Little is known however about relations between regulatory orientations and more general personality traits. The present paper reports results of the study in which regulatory foci are analyzed in the context of five factor model of personality. To measure personality traits the NEO-FFI was used. Promotion and prevention regulatory foci was a...

  18. 78 FR 54669 - Draft Environmental Impact Statement for the Proposed RES Americas Moapa Solar Energy Center...

    Science.gov (United States)

    2013-09-05

    ... Environmental Impact Statement for the Proposed RES Americas Moapa Solar Energy Center, Clark County, Nevada... environmental impact statement (DEIS) for the proposed RES Americas Moapa Solar Energy Center on the Moapa River... Progress and on the following Web site: www.MoapaSolarEnergyCenterEIS.com . In order to be fully considered...

  19. Res Publica kõrvaldas mässaja / Kristjan Roos

    Index Scriptorium Estoniae

    Roos, Kristjan, 1978-

    2005-01-01

    Tallinna linnavolikogu Res Publica fraktsiooni juhi kohalt, Res Publica Tallinna piirkonna juhatusest ja erakonna eestseisusest end taandanud Toomas Tautsi sõnul esitati talle erakonna eestseisuses mitmeid süüdistusi, mis kokkuvõtvalt olid etteheited tema vastuseisule võimalikule koalitsioonile Keskerakonnaga. Lisa: Abilinnapeadeks saavad Promm, Reivik ja Pevkur

  20. Res Publica Ida-Viru piirkond valis uue juhatuse / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje 4. dets. lk. 1. Res Publica Ida-Viru piirkonna üldkogul valiti uus juhatus, Vladimir Sarantsevi sõnul oli koosolek enamiku Kohtla-Järve osakonna liikmete arvates õigustühine. Res Publica peasekretäri Tõnis Konsi kommentaare

  1. Res Publica seisab vastu homse arvel elamisele / Siim Männik

    Index Scriptorium Estoniae

    Männik, Siim

    2005-01-01

    Ilmunud ka: Vabariik (venek.) 30. august lk. 1. Res Publica koostab praegu kohalikeks valimisteks nimekirju. Erakond ei plaani korraldada mitte ühte üleriigilist valimiskampaaniat, vaid 120 kohalikku kampaaniat, peale selle on kavas üleriigiline n.-ö. foonikampaania. Lisa: Miks valida Res Publica? Vt. samas: Sisevalimised 1.-3. septembrini

  2. Presidendilossis pidutses ka üks Res Publica liige / Kadri Jakobson

    Index Scriptorium Estoniae

    Jakobson, Kadri, 1970-

    2006-01-01

    SL Õhtulehele presidendilossis toimunud noortepidudest rääkinud neiu on Res Publica liige, kuid tema sõnul pole tema parteiline kuuluvus pidudega seotud. Arvamust avaldavad Res Publica juhatuse liige Andreas Kaju, erakonna esimees Taavi Veskimägi, ERL-i pressiesindaja Agu Uudelepp jt.

  3. Res Publica mängis topeltmängu / Risto Berendson

    Index Scriptorium Estoniae

    Berendson, Risto, 1975-

    2005-01-01

    Res Publica jätkab koostööd Tallinna linnavalitsuses Reformierakonnaga. Tallinna linnapea Tõnis Paltsi sõnul oli paralleelsete läbirääkimiste pidamine Keskerakonna ja Reformierakonnaga Res Publica Tallinna piirkonna juhatuse valitud taktika. Kommenteerib Jaanus Piirsalu

  4. Ühendpartei Res Publica tiib oli häältekogumisel Isamaast pisut edukam

    Index Scriptorium Estoniae

    2007-01-01

    Ühenderakonna Res Publica tiiva kandidaadid said Riigikogu valimistel umbes tuhat häält rohkem kui Isamaaliidu tiiva kandidaadid, samas oli IRL-i valimisnimekirjas Res Publica tiiva kandidaate ka mõne inimese võrra rohkem. Isamaaliidu edukaimad hääletoojad

  5. Res Publica lihtliikmed tõrjuvad Veskimäge / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2006-01-01

    Ilmunud ka: Pärnu Postimees 17. okt. lk. 6. Isamaa ja Res Publica liidu peaministrikandidaadiks sai Mart Laar, kuid pinged erakondade sees kestavad edasi. Res Publica opositsioon toetab isamaaliitlast Mart Laari ja on Taavi Veskimäe vastu. Lisa: Otsitakse peaministrit

  6. Epidemiology of Chronic Wasting Disease: PrP(res) Detection, Shedding, and Environmental Contamination

    National Research Council Canada - National Science Library

    Williams, Elizabeth S; Miller, Michael W; Lewis, Randolf V; Raisbeck, Merl F; Cook, Walter W

    2004-01-01

    .... The specific goals of these studies are to develop sensitive as says for PrP(exp res) as a marker for infectivity, and use these techniques to monitor the dynamics and modes of shedding of PrP(exp res...

  7. Res Publica nõuab veel üht abilinnapea kohta / Urmas Seaver

    Index Scriptorium Estoniae

    Seaver, Urmas, 1973-

    2005-01-01

    Tallinna linnapea Tõnis Palts on seisukohal, et Reformierakond surus koalitsiooni moodustamisel Res Publicale peale ebaõiglase vastutusvaldkondade jaotuse. Res Publica peasekretär Ott Lumi ei välista võimuliidu loomist Keskerakonnaga, kui Reformierakond järeleandmisi ei tee. ERL tegi ettepaneku kokku kutsuda erakondade ümarlaud. Vt. samas intervjuud Ott Lumiga

  8. As to achieve regulatory action, regulatory approaches

    International Nuclear Information System (INIS)

    Cid, R.; Encinas, D.

    2014-01-01

    The achievement of the effectiveness in the performance of a nuclear regulatory body has been a permanent challenge in the recent history of nuclear regulation. In the post-Fukushima era this challenge is even more important. This article addresses the subject from two complementary points of view: the characteristics of an effective regulatory body and the regulatory approaches. This work is based on the most recent studies carried out by the Committee on Nuclear Regulatory Activities, CNRA (OECD/NEA), as well as on the experience of the Consejo de Seguridad Nuclear, CSN, the Spanish regulatory body. Rafael Cid is the representative of CSN in these project: Diego Encinas has participated in the study on regulatory approaches. (Author)

  9. Research

    African Journals Online (AJOL)

    abp

    14 août 2012 ... par l'utilisation fréquente des médicaments de la dysfonction érectile ; ils ont en effet été associés à des comportements sexuels à risque [23] ; la méconnaissance des risques de transmission ... La mesure de l'observance a été évaluée sur les 24 dernières heures afin de limiter l'effet d'un éventuel biais de ...

  10. Research

    African Journals Online (AJOL)

    abp

    29 oct. 2013 ... nouveau-né et l'âge maternelle situé entre 20 et 34 ans, l'âge gestationnel inférieur à 37 SA, et le score d'APGAR<7, mais aussi le rôle d´autres facteurs tels que les .... mères ayant un âge gestationnel supérieur ou égal à 37 SA, il y a ... les nouveau-nés de poids de naissance normal, le score d'APGAR.

  11. Research

    African Journals Online (AJOL)

    ebutamanya

    28 avr. 2016 ... L'objectif de ce travail était de déterminer la proportion des AVC du sujet jeune, les facteurs de risque cérébro- vasculaire (FRCV) et de rechercher les facteurs prédictifs de .... utilisée était non probabiliste basée sur le recrutement consécutif des dossiers obéissant aux critères d'éligibilité. Les données.

  12. Hi-Res scan mode in clinical MDCT systems: Experimental assessment of spatial resolution performance.

    Science.gov (United States)

    Cruz-Bastida, Juan P; Gomez-Cardona, Daniel; Li, Ke; Sun, Heyi; Hsieh, Jiang; Szczykutowicz, Timothy P; Chen, Guang-Hong

    2016-05-01

    The introduction of a High-Resolution (Hi-Res) scan mode and another associated option that combines Hi-Res mode with the so-called High Definition (HD) reconstruction kernels (referred to as a Hi-Res/HD mode in this paper) in some multi-detector CT (MDCT) systems offers new opportunities to increase spatial resolution for some clinical applications that demand high spatial resolution. The purpose of this work was to quantify the in-plane spatial resolution along both the radial direction and tangential direction for the Hi-Res and Hi-Res/HD scan modes at different off-center positions. A technique was introduced and validated to address the signal saturation problem encountered in the attempt to quantify spatial resolution for the Hi-Res and Hi-Res/HD scan modes. Using the proposed method, the modulation transfer functions (MTFs) of a 64-slice MDCT system (Discovery CT750 HD, GE Healthcare) equipped with both Hi-Res and Hi-Res/HD modes were measured using a metal bead at nine different off-centered positions (0-16 cm with a step size of 2 cm); at each position, both conventional scans and Hi-Res scans were performed. For each type of scan and position, 80 repeated acquisitions were performed to reduce noise induced uncertainties in the MTF measurements. A total of 15 reconstruction kernels, including eight conventional kernels and seven HD kernels, were used to reconstruct CT images of the bead. An ex vivo animal study consisting of a bone fracture model was performed to corroborate the MTF results, as the detection of this high-contrast and high frequency task is predominantly determined by spatial resolution. Images of this animal model generated by different scan modes and reconstruction kernels were qualitatively compared with the MTF results. At the centered position, the use of Hi-Res mode resulted in a slight improvement in the MTF; each HD kernel generated higher spatial resolution than its counterpart conventional kernel. However, the MTF along the

  13. A global regulatory science agenda for vaccines.

    Science.gov (United States)

    Elmgren, Lindsay; Li, Xuguang; Wilson, Carolyn; Ball, Robert; Wang, Junzhi; Cichutek, Klaus; Pfleiderer, Michael; Kato, Atsushi; Cavaleri, Marco; Southern, James; Jivapaisarnpong, Teeranart; Minor, Philip; Griffiths, Elwyn; Sohn, Yeowon; Wood, David

    2013-04-18

    The Decade of Vaccines Collaboration and development of the Global Vaccine Action Plan provides a catalyst and unique opportunity for regulators worldwide to develop and propose a global regulatory science agenda for vaccines. Regulatory oversight is critical to allow access to vaccines that are safe, effective, and of assured quality. Methods used by regulators need to constantly evolve so that scientific and technological advances are applied to address challenges such as new products and technologies, and also to provide an increased understanding of benefits and risks of existing products. Regulatory science builds on high-quality basic research, and encompasses at least two broad categories. First, there is laboratory-based regulatory science. Illustrative examples include development of correlates of immunity; or correlates of safety; or of improved product characterization and potency assays. Included in such science would be tools to standardize assays used for regulatory purposes. Second, there is science to develop regulatory processes. Illustrative examples include adaptive clinical trial designs; or tools to analyze the benefit-risk decision-making process of regulators; or novel pharmacovigilance methodologies. Included in such science would be initiatives to standardize regulatory processes (e.g., definitions of terms for adverse events [AEs] following immunization). The aim of a global regulatory science agenda is to transform current national efforts, mainly by well-resourced regulatory agencies, into a coordinated action plan to support global immunization goals. This article provides examples of how regulatory science has, in the past, contributed to improved access to vaccines, and identifies gaps that could be addressed through a global regulatory science agenda. The article also identifies challenges to implementing a regulatory science agenda and proposes strategies and actions to fill these gaps. A global regulatory science agenda will enable

  14. Research

    African Journals Online (AJOL)

    Internship following graduation is an essential period for junior doctors to develop their ... The Health Professionals Council of SA (HPCSA) is the regulatory body ..... prescribing medication, communication and mental-state examinations were.

  15. RES hyperphagocytosis by rats with streptozotocin-induced diabetes mellitus.

    Science.gov (United States)

    Cornell, R P

    1981-03-01

    In contrast to previous studies of neutrophils from diabetic animals and humans in vitro and of macrophages from diabetic humans in vivo, which reported phagocytic depression, reticuloendothelial system (RES) hyperphagocytosis of colloidal carbon was observed in rats at 14 and 28 days after diabetes induction with streptozotocin (STZ). Carbon clearance half times were significantly enhanced to 6.3 +/- 0.79 and 8.1 +/- 1.04 min at 14 and 28 days post-STZ, respectively, compared with the nondiabetic value (12.7 +/- 0.98 min). The severity of uncontrolled STZ-induced diabetes in rats was confirmed by significant hypoinsulinemia, hyperglucagonemia, hyperglycemia, and hyperlipidemia. Although body weights of STZ-diabetic animals declined progressively, liver weights as a percent of body weight increased above the control value at 14 and 28 days post-STZ. In fact, expression of carbon phagocytosis as the corrected phagocytic index, which accounts for changes in liver and spleen weights relative to body weight, eliminated the significant difference between STZ-diabetic and nondiabetic animals. Antibiotic treatment of diabetic rats failed to alter the hyperphagocytosis, implying that a chronic bacterial infection was not the cause of phagocytic stimulation. Daily insulin replacements, but not a single large insulin dose to 14-day post-STZ rats, reversed the enhanced phagocytosis of colloidal carbon.

  16. Les frontières de la violence au Kenya

    Directory of Open Access Journals (Sweden)

    Claire Médard

    2008-03-01

    Full Text Available Au cours des violences post électorales récentes, au Kenya, de nombreux observateurs ont été surpris par la forme prise par les protestations partisanes. Elle nous rappelle que la fabrique territoriale de l’ethnicité est toujours d’actualité dans ce pays. La réactivation de frontières internes qui portent la marque des violences du passé, certaines héritées de la colonisation et d’autres renégociées depuis l’indépendance, ont mis en péril l’Etat.During the recent post electoral crisis in Kenya, the turn of the protest took many by surprise. We were reminded that the making of ethnicity is on ongoing process in which violence plays a part. New boundaries have appeared, re-enacting old divisions and creating new rifts. Once the mark of administration, internal boundaries now threaten the existence of the State.

  17. Intelligent energy buildings based on RES and nanotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Kaplanis, S., E-mail: kaplanis@teipat.gr; Kaplani, E. [R.E.S. Laboratory, Mechanical Engineering Dept., Technological Educational Institute of Western Greece M. Alexandrou 1, Koukouli 26 334, Patra (Greece)

    2015-12-31

    The paper presents the design features, the energy modelling and optical performance details of two pilot Intelligent Energy Buildings, (IEB). Both are evolution of the Zero Energy Building (ZEB) concept. RES innovations backed up by signal processing, simulation models and ICT tools were embedded into the building structures in order to implement a new predictive energy management concept. In addition, nano-coatings, produced by TiO2 and ITO nano-particles, were deposited on the IEB structural elements and especially on the window panes and the PV glass covers. They exhibited promising SSP values which lowered the cooling loads and increased the PV modules yield. Both pilot IEB units were equipped with an on-line dynamic hourly solar radiation prediction model, implemented by sensors and the related software to manage effectively the energy source, the loads and the storage or the backup system. The IEB energy sources covered the thermal loads via a south façade embedded in the wall and a solar roof which consists of a specially designed solar collector type, while a PV generator is part of the solar roof, like a compact BIPV in hybrid configuration to a small wind turbine.

  18. Big Data-Led Cancer Research, Application, and Insights.

    Science.gov (United States)

    Brown, James A L; Ni Chonghaile, Triona; Matchett, Kyle B; Lynam-Lennon, Niamh; Kiely, Patrick A

    2016-11-01

    Insights distilled from integrating multiple big-data or "omic" datasets have revealed functional hierarchies of molecular networks driving tumorigenesis and modifiers of treatment response. Identifying these novel key regulatory and dysregulated elements is now informing personalized medicine. Crucially, although there are many advantages to this approach, there are several key considerations to address. Here, we examine how this big data-led approach is impacting many diverse areas of cancer research, through review of the key presentations given at the Irish Association for Cancer Research Meeting and importantly how the results may be applied to positively affect patient outcomes. Cancer Res; 76(21); 6167-70. ©2016 AACR. ©2016 American Association for Cancer Research.

  19. A "Research" into International Student-Related Research: (Re)visualising Our Stand?

    Science.gov (United States)

    Abdullah, Doria; Abd Aziz, Mohd Ismail; Mohd Ibrahim, Abdul Latiff

    2014-01-01

    This paper uses Tight ("High Educ Res Dev" 23(4):395-411, 2004; "High Educ Res Dev" 31(5):723-740, 2012; "High Educ Res Dev" 32(1):136-151, 2013)'s journal analysis and review framework to review a sample of 497 journal articles on researches concerning international students over the past 30 years. It was found…

  20. Hydrogen-induced structural transition in single layer ReS2

    Science.gov (United States)

    Yagmurcukardes, M.; Bacaksiz, C.; Senger, R. T.; Sahin, H.

    2017-09-01

    By performing density functional theory-based calculations, we investigate how structural, electronic and mechanical properties of single layer ReS2 can be tuned upon hydrogenation of its surfaces. It is found that a stable, fully hydrogenated structure can be obtained by formation of strong S-H bonds. The optimized atomic structure of ReS2H2 is considerably different than that of the monolayer ReS2 which has a distorted-1T phase. By performing phonon dispersion calculations, we also predict that the Re2-dimerized 1T structure (called 1T {{}\\text{R{{\\text{e}}2}}} ) of the ReS2H2 is dynamically stable. Unlike the bare ReS2 the 1T {{}\\text{R{{\\text{e}}2}}} -ReS2H2 structure which is formed by breaking the Re4 clusters into separated Re2 dimers, is an indirect-gap semiconductor. Furthermore, mechanical properties of the 1T {{}\\text{R{{\\text{e}}2}}} phase in terms of elastic constants, in-plane stiffness (C) and Poisson ratio (ν) are investigated. It is found that full hydrogenation not only enhances the flexibility of the single layer ReS2 crystal but also increases anisotropy of the elastic constants.

  1. Professional and Regulatory Search

    Science.gov (United States)

    Professional and Regulatory search are designed for people who use EPA web resources to do their job. You will be searching collections where information that is not relevant to Environmental and Regulatory professionals.

  2. Technical support for the Ohio Clean Coal Technology Program. Volume 2, Baseline of knowledge concerning process modification opportunities, research needs, by-product market potential, and regulatory requirements: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Olfenbuttel, R.; Clark, S.; Helper, E.; Hinchee, R.; Kuntz, C.; Means, J.; Oxley, J.; Paisley, M.; Rogers, C.; Sheppard, W.; Smolak, L. [Battelle, Columbus, OH (United States)

    1989-08-28

    This report was prepared for the Ohio Coal Development Office (OCDO) under Grant Agreement No. CDO/R-88-LR1 and comprises two volumes. Volume 1 presents data on the chemical, physical, and leaching characteristics of by-products from a wide variety of clean coal combustion processes. Volume 2 consists of a discussion of (a) process modification waste minimization opportunities and stabilization considerations; (b) research and development needs and issues relating to clean coal combustion technologies and by-products; (c) the market potential for reusing or recycling by-product materials; and (d) regulatory considerations relating to by-product disposal or reuse.

  3. Res Publica jäi järjekordselt ilma mitmest nimekast liikmest / Tuuli Koch, Kärt Anvelt

    Index Scriptorium Estoniae

    Koch, Tuuli

    2005-01-01

    Oma lahkumiset Res Publicast teatasid erakonna esimene esimees Rein Taagepera, tema abikaasa Mare Taagepera, akadeemik Jaan Einasto ja 2002. aastal erakonna esimeheks kandideerinud Lauri Aaspõllu. Rein Taagepera põhjendas otsust Res Publica liikumisega paremtsentrist paremäärmusse. Lisa: Tuntud inimesi, kes seni Res Publicast lahkunud. Vt. samas lühiintervjuud Jaan Einastoga: Res Publica peab tegema koostööd

  4. Gestão integrada de resíduos : o impacto ambiental

    OpenAIRE

    Oliveira, Rosário

    2004-01-01

    Faz-se uma introducão à politica de gestão integrada de resíduos para enquadrar a valorização de resíduos como política desejável para assegurar um desenvolvimento sustentado. Referem-se de seguida metodologias para avaliação do impacto ambiental da utilização de resíduos que possam ser usados como materiais de construção civil e obras públicas, ressalvando-se alguma falta de enquadramento legal.

  5. Dynamique de fréquentation des grands mammifères dans une ...

    African Journals Online (AJOL)

    SARAH

    31 juil. 2016 ... RÉSUMÉ. Objectifs : Dans le but de connaitre les animaux fréquentant les clairières (ou Baï) forestières au Gabon, une étude sur la fréquentation du Baï de Momba par les grands mammifères a été conduite durant la petite saison des pluies pendant deux mois du 19 février au 13 mars 2012. Méthodologie ...

  6. Regulatory Expectations for Safety Culture

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Su Jin; Oh, Jang Jin; Choi, Young Sung [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2014-05-15

    The oversight of licensee's safety culture becomes an important issue that attracts great public and political concerns recently in Korea. Beginning from the intended violation of rules, a series of corruptions, documents forgery and disclosure of wrong-doings made the public think that the whole mindset of nuclear workers has been inadequate. Thus, they are demanding that safety culture shall be improved and that regulatory body shall play more roles and responsibilities for the improvements and oversight for them. This paper introduces, as an effort of regulatory side, recent changes in the role of regulators in safety culture, regulatory expectations on the desired status of licensee's safety culture, the pilot inspection program for safety culture and research activity for the development of oversight system. After the Fukushima accident in Japan 2011, many critics has searched for cultural factors that caused the unacceptable negligence pervaded in Japan nuclear society and the renewed emphasis has been placed on rebuilding safety culture by operators, regulators, and relevant institutions globally. Significant progress has been made in how to approach safety culture and led to a new perspective different from the existing normative assessment method both in operators and regulatory side. Regulatory expectations and oversight of them are based on such a new holistic concept for human, organizational and cultural elements to maintain and strengthen the integrity of defense in depth and consequently nuclear safety.

  7. Regulatory Expectations for Safety Culture

    International Nuclear Information System (INIS)

    Jung, Su Jin; Oh, Jang Jin; Choi, Young Sung

    2014-01-01

    The oversight of licensee's safety culture becomes an important issue that attracts great public and political concerns recently in Korea. Beginning from the intended violation of rules, a series of corruptions, documents forgery and disclosure of wrong-doings made the public think that the whole mindset of nuclear workers has been inadequate. Thus, they are demanding that safety culture shall be improved and that regulatory body shall play more roles and responsibilities for the improvements and oversight for them. This paper introduces, as an effort of regulatory side, recent changes in the role of regulators in safety culture, regulatory expectations on the desired status of licensee's safety culture, the pilot inspection program for safety culture and research activity for the development of oversight system. After the Fukushima accident in Japan 2011, many critics has searched for cultural factors that caused the unacceptable negligence pervaded in Japan nuclear society and the renewed emphasis has been placed on rebuilding safety culture by operators, regulators, and relevant institutions globally. Significant progress has been made in how to approach safety culture and led to a new perspective different from the existing normative assessment method both in operators and regulatory side. Regulatory expectations and oversight of them are based on such a new holistic concept for human, organizational and cultural elements to maintain and strengthen the integrity of defense in depth and consequently nuclear safety

  8. Res Publicat on täna vaja rohkem kui kunagi varem / Taavi Veskimägi

    Index Scriptorium Estoniae

    Veskimägi, Taavi, 1974-

    2005-01-01

    Res Publica esimees seab erakonnale ülesandeks selgitada inimestele, et Res Publicat võib usaldada. Ta selgitab, et Res Publica parempoolne poliitika tähendab ka hoolimist nendest, kes ei saa endaga hakkama. Vt. samas: Viimased kampaaniapäevad

  9. Future nuclear regulatory challenges

    International Nuclear Information System (INIS)

    Royen, J.

    1998-01-01

    In December 1996, the NEA Committee on Nuclear Regulatory Activities concluded that changes resulting from economic deregulation and other recent developments affecting nuclear power programmes have consequences both for licensees and regulatory authorities. A number of potential problems and issues which will present a challenge to nuclear regulatory bodies over the next ten years have been identified in a report just released. (author)

  10. Diagnóstico dos resíduos sólidos do setor agrossilvopastoril : resíduos sólidos inorgânicos

    OpenAIRE

    Rosseto, Renato

    2013-01-01

    Este trabalho buscou realizar o diagnóstico preliminar dos resíduos sólidos inorgânicos gerados no setor agrossilvopastoril, especialmente nos segmentos de agrotóxicos, fertilizantes, insumos farmacêuticos veterinários, além dos resíduos sólidos domésticos (RSDs) rurais Os assuntos foram separados em seções. De forma geral, a ausência de informações oficiais sistematizadas seguiu como a principal dificuldade em realizar o diagnóstico dos resíduos sólidos inorgânicos presentes no setor agrossi...

  11. Regulatory inspection of nuclear facilities and enforcement by the regulatory body. Safety guide

    International Nuclear Information System (INIS)

    2002-01-01

    The purpose of this Safety Guide is to provide recommendations for regulatory bodies on the inspection of nuclear facilities, regulatory enforcement and related matters. The objective is to provide the regulatory body with a high level of confidence that operators have the processes in place to ensure compliance and that they do comply with legal requirements, including meeting the safety objectives and requirements of the regulatory body. However, in the event of non-compliance, the regulatory body should take appropriate enforcement action. This Safety Guide covers regulatory inspection and enforcement in relation to nuclear facilities such as: enrichment and fuel manufacturing plants; nuclear power plants; other reactors such as research reactors and critical assemblies; spent fuel reprocessing plants; and facilities for radioactive waste management, such as treatment, storage and disposal facilities. This Safety Guide also covers issues relating to the decommissioning of nuclear facilities, the closure of waste disposal facilities and site rehabilitation. Section 2 sets out the objectives of regulatory inspection and enforcement. Section 3 covers the management of regulatory inspections. Section 4 covers the performance of regulatory inspections, including internal guidance, planning and preparation, methods of inspection and reports of inspections. Section 5 deals with regulatory enforcement actions. Section 6 covers the assessment of regulatory inspections and enforcement activities. The Appendix provides further details on inspection areas for nuclear facilities

  12. Regulatory activities; Actividades regulatorias

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This publication, compiled in 8 chapters, presents the regulatory system developed by the Nuclear Regulatory Authority (NRA) of the Argentine Republic. The following activities and developed topics in this document describe: the evolution of the nuclear regulatory activity in Argentina; the Argentine regulatory system; the nuclear regulatory laws and standards; the inspection and safeguards of nuclear facilities; the emergency systems; the environmental systems; the environmental monitoring; the analysis laboratories on physical and biological dosimetry, prenatal irradiation, internal irradiation, radiation measurements, detection techniques on nuclear testing, medical program on radiation protection; the institutional relations with national and international organization; the training courses and meeting; the technical information.

  13. Res Publica ja Isamaaliit ühendavad jõud / Urmo Kübar, Rauno Veri

    Index Scriptorium Estoniae

    Kübar, Urmo, 1978-

    2006-01-01

    Res Publica esimees Taavi Veskimägi ja Isamaaliidu esimees Tõnis Lukas kirjutasid alla ühiste kavatsuste deklaratsioonile, milles nad teevad ettepaneku moodustada ühine erakond. Lisad: Erakonna Eesti Eest deklaratsioon; Lühiülevaade ajaloost

  14. Res Publica üldkogu hääletab poliitilisi resolutsioone / Lauri Tankler

    Index Scriptorium Estoniae

    Tankler, Lauri

    2004-01-01

    Res Publica üldkogul hääletusele pandavate resolutsioonide eesmärgiks on teavitada avalikkust erakonna seisukohtadest. Olulisemad resolutsioonid on ette valmistatud ideoloogia, majanduse, hariduse ja sotsiaalpoliitika valdkonnas

  15. RES-E Support Policies In The Baltic States: Development Aspect (Part I

    Directory of Open Access Journals (Sweden)

    Bobinaite V.

    2015-02-01

    Full Text Available Despite quite similar conditions (natural resources for electricity production from renewable energy sources (RES-E in three Baltic States (Estonia, Latvia and Lithuania, significant differences exist in these countries as to the RES-E production volume. In Latvia this volume is the highest, while in Estonia and Lithuania it is half as high. One of the factors that determine the RES-E production volumes is support policies, which in the Baltic States are different. The main objective of this work was to analyze and compare these support policies. The results have shown that for rapid RES-E development the most effective policy is to be market-oriented (as in Estonia, whereas for more stable development such policy should be producer-oriented (as in Lithuania.

  16. Res Publica nõuab Leinatammelt 44 600 krooni / Kadri Jakobson

    Index Scriptorium Estoniae

    Jakobson, Kadri, 1970-

    2005-01-01

    Res Publica nõuab Reformierakonda üle läinud Tarmo Leinatammelt maksmata jäänud liikmemaksu, fraktsioon kutsub teda üles loobuma kohast Riigikogus. Erakonna pressiesindaja Riina Vändre selgitus

  17. Res Publica tahab muuta Riigikogu kuluhüvitiste süsteemi / Alari Rammo

    Index Scriptorium Estoniae

    Rammo, Alari

    2003-01-01

    Riigikogu Res Publica fraktsiooni ettepanekutest reformida Riigikogu liikmetele ette nähtud kuluhüvitiste süsteemi. Tabel: Kasutatud kuluhüvitised seisuga 15. oktoober 2003. Kommenteerib Urmo Kübar

  18. Rationales for technology-specific RES support and their relevance for German policy

    International Nuclear Information System (INIS)

    Gawel, Erik; Lehmann, Paul; Purkus, Alexandra; Söderholm, Patrik; Witte, Katherina

    2017-01-01

    In order to achieve cost-effective RES-E deployment it is often argued that technology-neutral support schemes for renewables are indispensable. Against this background, RES-E support policies making widely use of technology differentiation in remuneration settings, e.g. across the EU, are frequently criticized from a theoretical point of view. However, in this paper we provide a systematic critique of the technology neutrality concept as a foundation for designing policy support schemes in the RES-E technology field. Specifically, the main objective of the paper is to scrutinize the arguments for technology-neutrality, and discuss three conceptual arguments for why technology-specific support schemes could in fact help minimize the societal costs of reaching future RES-E targets. We also briefly address different political economy concerns, which could constrain the choice of cost-effective policy support schemes, and that have to be taken into account for economic policy advice. For empirical illustration of the key arguments we refer to the case of German RES-E policy-making. The central conclusion from this paper is that technology-specific RES-E support schemes may generate significant economic benefits, particularly if technology markets work imperfectly and in second-best policy settings with additional non-internalized market failures. - Highlights: • Three theoretical cost-effectiveness reasons for technology-specific RES-E support. • German case study to show relevance of theoretical arguments for policy-making. • Political economy constraints to technology-neutral support are demonstrated. • Technology-specific RES-E support may generate significant economic benefits.

  19. Comment rendre les villes plus sûres | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    29 oct. 2015 ... À mi-chemin d'un programme quinquennal de recherche, les experts qui travaillent à l'initiative Villes sûres et inclusives font la lumière sur ce qui fonctionne – et ne fonctionne pas – pour rendre les villes plus sûres. Le présent compte rendu présente certains enseignements tirés de leur travail, ainsi que ...

  20. Ressources minières en Afrique : Quelle réglementation pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ressources minières en Afrique : Quelle réglementation pour le développement ? Couverture du livre Ressources minières en Afrique : Quelle réglementation pour le développement ? Directeur(s):. Bonnie Campbell. Maison(s) d'édition: Presses de l'Université du Québec, CRDI. 6 juillet 2009. ISBN : 9782760525214.

  1. The performances of standard and ResMed masks during bag-valve-mask ventilation.

    Science.gov (United States)

    Lee, Hyoung Youn; Jeung, Kyung Woon; Lee, Byung Kook; Lee, Seung Joon; Jung, Yong Hun; Lee, Geo Sung; Min, Yong Il; Heo, Tag

    2013-01-01

    A tight mask seal is frequently difficult to obtain and maintain during single-rescuer bag-valve-mask (BVM) ventilation. The ResMed mask (Bella Vista, NSW, Australia) is a continuous-positive-airway-pressure mask (CM) designed for noninvasive ventilation. In this study, we compared the ventilation performances of a standard mask (SM) and a ResMed CM using a simulation manikin in an out-of-hospital single-rescuer BVM ventilation scenario. Thirty emergency medical technicians (EMTs) performed two 2-minute attempts to ventilate a simulation manikin using BVM ventilation, alternatively, with the SM or the ResMed CM in a randomized order. Ventilation parameters including tidal volume and peak airway pressure were measured using computer analysis software connected to the simulation manikin. Successful volume delivery was defined as delivery of 440-540 mL of tidal volume in accord with present cardiopulmonary resuscitation guidelines. BVM ventilation using the ResMed CM produced higher mean (± standard deviation) tidal volumes (452 ± 50 mL vs. 394 ± 113 mL, p = 0.014) and had a higher proportion of successful volume deliveries (65.3% vs. 26.7%, p < 0.001) than that using the SM. Peak airway pressure was higher in BVM ventilation using the ResMed CM (p = 0.035). Stomach insufflation did not occur during either method. Twenty-nine of the participants (96.7%) preferred BVM ventilation using the ResMed CM. BVM ventilations using ResMed CM resulted in a significantly higher proportion of successful volume deliveries meeting the currently recommended range of tidal volume. Clinical studies are needed to determine the value of the ResMed CM for BVM ventilation.

  2. Isamaa ja Res Publica liit tõotab neile kõrget kohta edetabelis / Rasmus Kagge

    Index Scriptorium Estoniae

    Kagge, Rasmus, 1977-

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke 10. apr. lk. 7. TNS Emori märtsikuu erakondade populaarsusuuringu tulemused näitavad, et Res Publicaga liituda otsustanud Isamaaliit on tõusnud poliitedetabelis kolmandale kohale. Res Publica reiting on endiselt madal, edetabelit juhib Keskerakond. Diagrammid: Isamaaliit kogub toetajaid tõusvas tempos. Vt. samas: Ühendpartei Eesti Eest! otsib endale uut nime

  3. Liquefied natural gas tender crashworthiness research

    Science.gov (United States)

    2015-03-23

    Research is being conducted to develop technical : information needed to formulate effective natural gas fuel : tender crashworthiness standards. This research is being : performed for the Federal Railroad Administrations (FRAs) : Office of Res...

  4. Biossorção de azul de metileno utilizando resíduos agroindustriais

    Directory of Open Access Journals (Sweden)

    Andressa C. Honorato

    2015-07-01

    Full Text Available O presente trabalho avaliou a capacidade de adsorção do corante azul de metileno nos resíduos da palha de milho e da bainha do palmito pupunha in natura. A caracterização dos resíduos foi determinada utilizando-se a microscopia eletrônica de varredura e espectroscopia na região do infravermelho a qual indicou a presença de grupos carboxílicos, hidroxila e carbonila. O tempo necessário para que o sistema atingisse o equilíbrio para ambos os resíduos foi de 240 min, seguindo uma cinética descrita pelo modelo de pseudo-segunda ordem. A capacidade máxima de adsorção foi de 102,8 mg g-1 para o resíduo da palha de milho, seguindo o modelo de isoterma de Langmuir e 50,9 mg g-1 para o resíduo de palmito pupunha, sendo que o modelo que melhor se ajusta foi Freundlich. Desta forma, esses resíduos são promissores para a adsorção do corante azul de metileno em efluentes.

  5. Revisiting long-run relations in power markets with high RES penetration

    International Nuclear Information System (INIS)

    Gianfreda, Angelica; Parisio, Lucia; Pelagatti, Matteo

    2016-01-01

    Electricity generation from renewable energy resources (RES) has become increasingly significant to reach EU and emissions reduction targets. At the same time, one of the main EU policy goals has been the creation of a common internal energy market for Europe. In this paper, we focus on these two issues previously studied separately, considering their possible interactions. We first analyze the long-run relationship between day-ahead electricity prices and fuel prices (natural gas and coal) looking at two samples of years characterized by low and high RES penetration, then we explore the integration of EU markets. We show that the electricity–fuel nexus found over 2006–2008 changed dramatically over 2010–2014 for the majority of countries considered. In particular, the long-run dependence of electricity from gas and coal prices is much lower in recent years. Furthermore, our results confirm that the considered EU countries are becoming less integrated as RES-E increases. Our findings suggest that nationally implemented policies to support renewables are successful in increasing RES penetration, but they have lessened the linkage among EU markets, then making integration more difficult to obtain. - Highlights: •RES lower the intra-daily electricity dependence from coal and natural gas. •RES affect the EU wholesale electricity market integration, studied at hourly level. •Overlapping national and supranational policies tackle the achievement of EU targets. •Strong policy coordination is required to avoid that the “greens” promote the “dirtiest”.

  6. Epitaxial growth of ReS2(001) thin film via deposited-Re sulfurization

    Science.gov (United States)

    Urakami, Noriyuki; Okuda, Tetsuya; Hashimoto, Yoshio

    2018-02-01

    In this paper, we present the formation of large-size rhenium disulfide (ReS2) films via the sulfurization of Re films deposited on sapphire substrates. The effects of sulfurization temperature and pressure on the crystal quality were investigated. A [001]-oriented single crystal of ReS2 films with 6 × 10 mm2 area was realized. By sulfurizing Re films at 1100 °C, ReS2 films with well-defined sharp interfaces to c-plane sapphire substrates could be formed. Below and above the sulfurization temperature of 1100 °C, incomplete sulfurization and film degradation were observed. The twofold symmetry of the monocrystalline in-plane structure composed of Re-Re bonds along with Re-S bonds pointed to a distorted 1T structure, indicating that this structure is the most stable atomic arrangement for ReS2. For a S/Re compositional ratio equal to or slightly lower than 2.0, characteristic Raman vibrational modes with the narrowest line widths were observed. The typical absorption peak of ReS2 can be detected at 1.5 eV.

  7. Regulatory Control of Radiation Sources. Safety Guide (Arabic Edition)

    International Nuclear Information System (INIS)

    2012-01-01

    This Safety Guide is intended to assist States in implementing the requirements established in Safety Standards Series No. GS-R-1, Legal and Governmental Infrastructure for Nuclear, Radiation, Radioactive Waste and Transport Safety, for a national regulatory infrastructure to regulate any practice involving radiation sources in medicine, industry, research, agriculture and education. The Safety Guide provides advice on the legislative basis for establishing regulatory bodies, including the effective independence of the regulatory body. It also provides guidance on implementing the functions and activities of regulatory bodies: the development of regulations and guides on radiation safety; implementation of a system for notification and authorization; carrying out regulatory inspections; taking necessary enforcement actions; and investigating accidents and circumstances potentially giving rise to accidents. The various aspects relating to the regulatory control of consumer products are explained, including justification, optimization of exposure, safety assessment and authorization. Guidance is also provided on the organization and staffing of regulatory bodies. Contents: 1. Introduction; 2. Legal framework for a regulatory infrastructure; 3. Principal functions and activities of the regulatory body; 4. Regulatory control of the supply of consumer products; 5. Functions of the regulatory body shared with other governmental agencies; 6. Organization and staffing of the regulatory body; 7. Documentation of the functions and activities of the regulatory body; 8. Support services; 9. Quality management for the regulatory system.

  8. Regulatory control of nuclear power plants

    International Nuclear Information System (INIS)

    2002-01-01

    The purpose of this book is to support IAEA training courses and workshops in the field of regulatory control of nuclear power plants as well as to support the regulatory bodies of Member States in their own training activities. The target group is the professional staff members of nuclear safety regulatory bodies supervising nuclear power plants and having duties and responsibilities in the following regulatory fields: regulatory framework; regulatory organization; regulatory guidance; licensing and licensing documents; assessment of safety; and regulatory inspection and enforcement. Important topics such as regulatory competence and quality of regulatory work as well as emergency preparedness and public communication are also covered. The book also presents the key issues of nuclear safety such as 'defence-in-depth' and safety culture and explains how these should be taken into account in regulatory work, e.g. during safety assessment and regulatory inspection. The book also reflects how nuclear safety has been developed during the years on the basis of operating experience feedback and results of safety research by giving topical examples. The examples cover development of operating procedures and accident management to cope with complicated incidents and severe accidents to stress the importance of regulatory role in nuclear safety research. The main target group is new staff members of regulatory bodies, but the book also offers good examples for more experienced inspectors to be used as comparison and discussion basis in internal workshops organized by the regulatory bodies for refreshing and continuing training. The book was originally compiled on the basis of presentations provided during the two regulatory control training courses in 1997 and 1998. The textbook was reviewed at the beginning of the years 2000 and 2002 by IAEA staff members and consistency with the latest revisions of safety standards have been ensured. The textbook was completed in the

  9. In Search of the 'New Informal Legitimacy' of Médecins Sans Frontières.

    Science.gov (United States)

    Calain, Philippe

    2012-04-01

    FOR MEDICAL HUMANITARIAN ORGANIZATIONS, MAKING THEIR SOURCES OF LEGITIMACY EXPLICIT IS A USEFUL EXERCISE, IN RESPONSE TO: misperceptions, concerns over the 'humanitarian space', controversies about specific humanitarian actions, challenges about resources allocation and moral suffering among humanitarian workers. This is also a difficult exercise, where normative criteria such as international law or humanitarian principles are often misrepresented as primary sources of legitimacy. This essay first argues for a morally principled definition of humanitarian medicine, based on the selfless intention of individual humanitarian actors. Taking Médecins Sans Frontières (MSF) as a case in point, a common source of moral legitimacy for medical humanitarian organizations is their cosmopolitan appeal to distributive justice and collective responsibility. More informally, their legitimacy is grounded in the rightfulness of specific actions and choices. This implies a constant commitment to publicity and accountability. Legitimacy is also generated by tangible support from the public to individual organizations, by commitments to professional integrity, and by academic alliances to support evidence-based practice and operational research.

  10. Meeting the regulatory information needs of users of radioactive materials

    International Nuclear Information System (INIS)

    MacDurmon, G.W.

    1996-01-01

    The use of radioactive materials is one of the most regulated areas of research. Researchers face ever increasing regulatory requirements and issues involving the disposal of radioactive material, while meeting the demands of higher productivity. Radiation safety programs must maximize regulatory compliance, minimize barriers, provide services and solutions, and effectively communicate with users of radioactive materials. This talk will discuss methods by which a radiation safety program can meet the needs of both the research staff and regulatory compliance staff

  11. Meeting the regulatory information needs of users of radioactive materials

    Energy Technology Data Exchange (ETDEWEB)

    MacDurmon, G.W. [American Cyanamid Company, Princeton, NJ (United States)

    1996-10-01

    The use of radioactive materials is one of the most regulated areas of research. Researchers face ever increasing regulatory requirements and issues involving the disposal of radioactive material, while meeting the demands of higher productivity. Radiation safety programs must maximize regulatory compliance, minimize barriers, provide services and solutions, and effectively communicate with users of radioactive materials. This talk will discuss methods by which a radiation safety program can meet the needs of both the research staff and regulatory compliance staff.

  12. Information resources in state regulatory agencies-a California perspective

    Energy Technology Data Exchange (ETDEWEB)

    DiZio, S.M. [California Environmental Protection Agency, Sacramento (United States)

    1990-12-31

    Various state regulatory agencies have expressed a need for networking with information gatherers/researchers to produce a concise compilation of primary information so that the basis for regulatory standards can be scientifically referenced. California has instituted several programs to retrieve primary information, generate primary information through research, and generate unique regulatory standards by integrating the primary literature and the products of research. This paper describes these programs.

  13. Regulatory Commission of Alaska

    Science.gov (United States)

    Map Help Regulatory Commission of Alaska Login Forgot Password Arrow Image Forgot password? View Cart login Procedures for Requesting Login For Consumers General Information Telephone Electric Natural Gas

  14. Regulatory aspects of emergency planning

    International Nuclear Information System (INIS)

    Jamgochian, M.T.

    1986-01-01

    The paper discusses the advances that have been made in the USA in the field of emergency planning over the past several years and considers regulatory changes that may be on the horizon. The paper examines the importance of severe accident source terms and their relationship to emergency preparedness, recent research results of work on source terms, and the experience gained from evaluation of licensee performance during annual emergency preparedness exercises. (author)

  15. Regulatory and institutional challenges of corporate governance in ...

    African Journals Online (AJOL)

    Regulatory and institutional challenges of corporate governance in post banking consolidation Nigeria. ... PROMOTING ACCESS TO AFRICAN RESEARCH ... From a banking industry perspective, good corporate governance demands

  16. United States Nuclear Regulatory Commission research program on core debris/concrete interactions and ex-vessel fission-product release

    International Nuclear Information System (INIS)

    Burson, S.B.

    1987-01-01

    The study of core debris/concrete interaction phenomena has been a significant element of the NRC's Severe Accident Research Program for a number of years. The CORCON and VANESA codes used to predict the consequences of high-temperature debris attack on concrete and fission-product aerosol release are state-of-the-art computational tools. The major thrust of current NRC sponsored research focuses on the refinement, verification, and validation of these codes. An overview of the analytical and experimental aspects of the NRC research program is presented

  17. Legal principles of regulatory administration and nuclear safety regulation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyeong Hui; Cheong, Sang Kee [Hannam Univ., Taejon (Korea, Republic of)

    2000-12-15

    This research presents a critical analysis and evaluation of principles of administrative laws in order to provide framework of structural reform on the nuclear safety regulation system. The focus of this analysis and evaluation is centered around the area of origin of regulatory administrative laws; authorities of regulation; procedures of regulatory actions; regulatory enforcement; and administrative relief system. In chapter 2 the concept of regulatory administration is analysed. Chapter 3 identifies the origin of regulatory administration and the principles of administration laws. It also examines legal nature of the nuclear safety standard. In relation to regulatory authorities. Chapter 4 identifies role and responsibility of administration authorities and institutions. It also examines fundamental principles of delegation of power. Then the chapter discusses the nuclear safety regulation authorities and their roles and responsibilities. Chapter 5 classifies and examines regulatory administration actions. Chapter 6 evaluates enforcement measure for effectiveness of regulation. Finally, chapter 7 discusses the administrative relief system for reviewing unreasonable regulatory acts.

  18. Communication Regulatory Science: Mapping a New Field.

    Science.gov (United States)

    Noar, Seth M; Cappella, Joseph N; Price, Simani

    2017-12-13

    Communication regulatory science is an emerging field that uses validated techniques, tools, and models to inform regulatory actions that promote optimal communication outcomes and benefit the public. In the opening article to this special issue on communication and tobacco regulatory science, we 1) describe Food and Drug Administration (FDA) regulation of tobacco products in the US; 2) introduce communication regulatory science and provide examples in the tobacco regulatory science realm; and 3) describe the special issue process and final set of articles. Communication research on tobacco regulatory science is a burgeoning area of inquiry, and this work advances communication science, informs and potentially guides the FDA, and may help to withstand legal challenges brought by the tobacco industry. This research has the potential to have a major impact on the tobacco epidemic and population health by helping implement the most effective communications to prevent tobacco initiation and increase cessation. This special issue provides an example of 10 studies that exemplify tobacco regulatory science and demonstrate how the health communication field can affect regulation and benefit public health.

  19. Regulatory governance of telecommunications liberalisation in Taiwan

    International Nuclear Information System (INIS)

    Cheng, Kuo-Tai; Hebenton, Bill

    2008-01-01

    This paper examines the changing role of government and market in regulating the telecommunications sector from since 1996 in Taiwan. It contextualises the theoretical aspects of regulatory governance for institutional design and practices, and reviews the concepts and mechanisms for appraising privatisation and regulatory systems. Using a conceptual framework for researching privatisation and regulation, it describes the process and issues pertinent to telecommunications liberalisation and privatisation in Taiwan, supported by a brief presentation of theoretical points of view as well as practitioners' views. The paper presents results concerning criteria for appraising privatisation and regulatory governance and considers policy lessons that can be learned from the experiences of the Taiwanese telecommunications sector's liberalisation. (author)

  20. Unraveling the Raman Enhancement Mechanism on 1T'-Phase ReS2 Nanosheets.

    Science.gov (United States)

    Miao, Peng; Qin, Jing-Kai; Shen, Yunfeng; Su, Huimin; Dai, Junfeng; Song, Bo; Du, Yunchen; Sun, Mengtao; Zhang, Wei; Wang, Hsing-Lin; Xu, Cheng-Yan; Xu, Ping

    2018-04-01

    2D transition metal dichalcogenides materials are explored as potential surface-enhanced Raman spectroscopy substrates. Herein, a systematic study of the Raman enhancement mechanism on distorted 1T (1T') rhenium disulfide (ReS 2 ) nanosheets is demonstrated. Combined Raman and photoluminescence studies with the introduction of an Al 2 O 3 dielectric layer unambiguously reveal that Raman enhancement on ReS 2 materials is from a charge transfer process rather than from an energy transfer process, and Raman enhancement is inversely proportional while the photoluminescence quenching effect is proportional to the layer number (thickness) of ReS 2 nanosheets. On monolayer ReS 2 film, a strong resonance-enhanced Raman scattering effect dependent on the laser excitation energy is detected, and a detection limit as low as 10 -9 m can be reached from the studied dye molecules such as rhodamine 6G and methylene blue. Such a high enhancement factor achieved through enhanced charge interaction between target molecule and substrate suggests that with careful consideration of the layer-number-dependent feature and excitation-energy-related resonance effect, ReS 2 is a promising Raman enhancement platform for sensing applications. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. A study on the electronic and interfacial structures of monolayer ReS2-metal contacts.

    Science.gov (United States)

    Wang, Jin; Yang, Guofeng; Sun, Rui; Yan, Pengfei; Lu, Yanan; Xue, Junjun; Chen, Guoqing

    2017-10-11

    In this paper, we perform a systematic and rigorous study to evaluate the Ohmic nature of the top-contact formed by the monolayer ReS 2 (mReS 2 ) and metals (gold, silver, platinum, nickel, titanium, and scandium) by means of first-principles density functional theory calculations. We investigate the potential barrier, charge transfer and atomic orbital overlap at the mReS 2 -metal interface in consideration of van der Waals forces to understand how efficiently carriers could be injected from the metal contact to the mReS 2 channel. ReS 2 is physisorbed on Au and Ag, which leads to little perturbation of its electronic structures and forms a larger Schottky contact and a higher tunnel barrier at the interface. ReS 2 is chemisorbed on Ti and Sc, where the bonding strongly perturbs the electronic structures and is found to be purely Ohmic. The bonding of ReS 2 on Pt and Ni lies between these two extreme cases, demonstrating an intermediate behavior. These findings not only provide an insight into the mReS 2 -metal interfaces but may also prove to be instrumental in the future design of ReS 2 -based devices with good performance.

  2. NRC Regulatory Agenda

    International Nuclear Information System (INIS)

    1991-10-01

    The NRC Regulatory Agenda is a compilation of all rules on which the NRC has recently completed action, or has proposed action, or is considering action, and all petitions for rulemaking which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  3. NRC regulatory agenda

    International Nuclear Information System (INIS)

    1993-04-01

    The NRC Regulatory Agenda is a compilation of all rules on which the NRC has recently completed action, or has proposed action, or is considering action, and all petitions for rulemaking which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  4. NRC regulatory agenda

    International Nuclear Information System (INIS)

    1990-01-01

    The NRC Regulatory Agenda is a compilation of all rules on which the NRC has proposed or is considering action and all petitions for rulemaking which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  5. NRC regulatory agenda

    International Nuclear Information System (INIS)

    1991-04-01

    The NRC Regulatory Agenda is a compilation of all rules on which the NRC has recently completed action or has proposed, or is considering action and all petitions for rulemaking which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  6. NRC Regulatory Agenda

    International Nuclear Information System (INIS)

    1991-08-01

    The NRC Regulatory Agenda is a compilation of all rules on which the NRC has recently completed action or has proposed, or is considering action and all petitions for rulemaking which have been received by the commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  7. Trust in regulatory regimes

    NARCIS (Netherlands)

    Six, Frédérique; Verhoest, Koen

    2017-01-01

    Within political and administrative sciences generally, trust as a concept is contested, especially in the field of regulatory governance. This groundbreaking book is the first to systematically explore the role and dynamics of trust within regulatory regimes. Conceptualizing, mapping and analyzing

  8. Nuclear Regulatory legislation

    International Nuclear Information System (INIS)

    1984-06-01

    This compilation of statutes and material pertaining to nuclear regulatory legislation through the 97th Congress, 2nd Session, has been prepared by the Office of the Executive Legal Director, U.S. Nuclear Regulatory Commission, with the assistance of staff, for use as an internal resource document

  9. Improving nuclear regulatory effectiveness

    International Nuclear Information System (INIS)

    2001-01-01

    Ensuring that nuclear installations are operated and maintained in such a way that their impact on public health and safety is as low as reasonably practicable has been and will continue to be the cornerstone of nuclear regulation. In the past, nuclear incidents provided the main impetus for regulatory change. Today, economic factors, deregulation, technological advancements, government oversight and the general requirements for openness and accountability are leading regulatory bodies to review their effectiveness. In addition, seeking to enhance the present level of nuclear safety by continuously improving the effectiveness of regulatory bodies is seen as one of the ways to strengthen public confidence in the regulatory systems. This report covers the basic concepts underlying nuclear regulatory effectiveness, advances being made and future requirements. The intended audience is primarily nuclear safety regulators, but government authorities, nuclear power plant operators and the general public may also be interested. (author)

  10. Netzwerk-Broker als interdisziplinäres Forschungsthema

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Leick, Birgit

    2018-01-01

    Sandelowski 2000 and 1997, and Howell Major and Savin-Baden 2010). This book chapter is introducing into the method based on an example - the support of brokerage of governance in company networks - from the entrepreneurship-research. Meta-synthesis is suited to synthesize and aggregate case......-based, qualitative empirical research, aggregate that needs interpretation on the meta-level and contributes to theory-building....

  11. Development of regulatory policy for SMART-P

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S. H.; Lee, Y. H.; Moo, Philip; Koh, B. J.; Son, M. K.; Han, G. H.; Kim, D. H. [Korea Association for Nuclear Technology, Daejeon (Korea, Republic of)

    2004-06-15

    KAERI promoted the construction of a research reactor, SMART-P, the reduced scale of SMART, with intent to demonstrate the safety and performance of SMART. According to this progress, the development of regulatory process for SMART-P became necessary. The establishment of regulatory policy, based on the current regulatory guidelines as well as technical aspect, became essential matters. Considering the on-going small and medium size reactors in near future, the selection of the appropriate measure in the existing regulatory process to SMART-P is very important. Thus the schematic study for the applicable licensing procedure and regulatory requirements suitable for SMART-P is required.

  12. Development of regulatory policy for SMART-P

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S. H.; Moon, S. H.; Lee, Y. H.; Son, M. K.; Han, K. H.; Kim, D. H. [Korea Association for Nuclear Technology, Taejon (Korea, Republic of)

    2003-06-15

    KAERI promoted the construction of a research reactor, SMART-P, the reduced scale of SMART, with intent to demonstrate the safety and performance of SMART. According to this progress, the development of regulatory process for SMART-P became necessary. The establishment of regulatory policy, based on the current regulatory guidelines as well as technical aspect, became essential matters. Considering the on-going small and medium size reactors m near future, the selection of the appropriate measure in the existing regulatory process to SMART-P is very important. Thus the schematic study for the applicable licensing procedure and regulatory requirements suitable for SMART-P is required.

  13. Room temperature synthesis of ReS2 through aqueous perrhenate sulfidation

    Science.gov (United States)

    Borowiec, Joanna; Gillin, William P.; Willis, Maureen A. C.; Boi, Filippo S.; He, Y.; Wen, J. Q.; Wang, S. L.; Schulz, Leander

    2018-02-01

    In this study, a direct sulfidation reaction of ammonium perrhenate (NH4ReO4) leading to a synthesis of rhenium disulfide (ReS2) is demonstrated. These findings reveal the first example of a simplistic bottom-up approach to the chemical synthesis of crystalline ReS2. The reaction presented here takes place at room temperature, in an ambient and solvent-free environment and without the necessity of a catalyst. The atomic composition and structure of the as-synthesized product were characterized using several analysis techniques including energy dispersive x-ray spectroscopy, x-ray photoelectron spectroscopy, x-ray diffraction, transmission electron microscopy, Raman spectroscopy, thermogravimetric analysis and differential scanning calorimetry. The results indicated the formation of a lower symmetry (1Tʹ) ReS2 with a low degree of layer stacking.

  14. Automatic white blood cell classification using pre-trained deep learning models: ResNet and Inception

    Science.gov (United States)

    Habibzadeh, Mehdi; Jannesari, Mahboobeh; Rezaei, Zahra; Baharvand, Hossein; Totonchi, Mehdi

    2018-04-01

    This works gives an account of evaluation of white blood cell differential counts via computer aided diagnosis (CAD) system and hematology rules. Leukocytes, also called white blood cells (WBCs) play main role of the immune system. Leukocyte is responsible for phagocytosis and immunity and therefore in defense against infection involving the fatal diseases incidence and mortality related issues. Admittedly, microscopic examination of blood samples is a time consuming, expensive and error-prone task. A manual diagnosis would search for specific Leukocytes and number abnormalities in the blood slides while complete blood count (CBC) examination is performed. Complications may arise from the large number of varying samples including different types of Leukocytes, related sub-types and concentration in blood, which makes the analysis prone to human error. This process can be automated by computerized techniques which are more reliable and economical. In essence, we seek to determine a fast, accurate mechanism for classification and gather information about distribution of white blood evidences which may help to diagnose the degree of any abnormalities during CBC test. In this work, we consider the problem of pre-processing and supervised classification of white blood cells into their four primary types including Neutrophils, Eosinophils, Lymphocytes, and Monocytes using a consecutive proposed deep learning framework. For first step, this research proposes three consecutive pre-processing calculations namely are color distortion; bounding box distortion (crop) and image flipping mirroring. In second phase, white blood cell recognition performed with hierarchy topological feature extraction using Inception and ResNet architectures. Finally, the results obtained from the preliminary analysis of cell classification with (11200) training samples and 1244 white blood cells evaluation data set are presented in confusion matrices and interpreted using accuracy rate, and false

  15. Valorisation par voie hydrométallurgique de Matières Premières Secondaires Valorization of Secondary Raw Materials by hydrometallurgical way

    Directory of Open Access Journals (Sweden)

    Meux Eric

    2013-11-01

    Full Text Available Cet exposé s'intéressera à la récupération par voie hydrométallurgique de métaux contenus dans les Matières Premières Secondaires. Dans un premier temps seront abordées des généralités sur les Métaux Critiques, leur taux de recyclage et les gisements identifiés. Deux exemples de traitement seront ensuite développés : le traitement de catalyseurs d'hydrotraitement et le traitement de poudres métallifères issues de broyats d'accumulateurs par couplage électrolixiviation/électrodéposition. This talk will focus on the hydrometallurgical recovery of metals contained in secondary raw materials. At first, generalities about critical metals, their recycling rate and their identified supply will be addressed. Two examples of hydrometallurgical treatment will be then developed: the treatment of spent hydrotreating catalysts and the treatment of electrodes powders coming from grinding of spent batteries by coupling electroleaching/electrodeposition.

  16. Revisiting support policies for RES-E adulthood: Towards market compatible schemes

    International Nuclear Information System (INIS)

    Huntington, Samuel C.; Rodilla, Pablo; Herrero, Ignacio; Batlle, Carlos

    2017-01-01

    The past two decades of growth in renewable energy sources of electricity (RES-E) have been largely driven by out-of-market support policies. These schemes were designed to drive deployment on the basis of specific subsidies sustained in time to allow for the larger costs as well as to limit investor risk. While these policies have proven to be effective, the way they have been designed to date has led to costly market distortions that are becoming more difficult to ignore as penetrations reach unpreceded levels. In the context of this growing concern, we provide a critical analysis of the design elements of RES-E support schemes, focusing on how they affect this trade-off between promoting and efficiently integrating RES-E. The emphasis is on the structure of the incentive payment, which in the end turns to be the cornerstone for an efficient integration. We conclude that, while needed, a well-designed and further developed capacity-based support mechanism complemented with ex-post compensations defined for reference benchmark plants, such as the mechanism currently implemented in Spain, is an alternative with good properties if the major goal is truly market integration. The approach is robust to future developments in technology cost, performance and market penetration of RES-E. - Highlights: • Market distortions due to RES support mechanisms are becoming difficult to ignore. • This paper provides a critical analysis of the design elements of RES support schemes. • The emphasis is on the structure of the incentive, key for an efficient integration. • We argue in favor of a further developed capacity-based support mechanism. • The incentive should be combined with the design of a set of reference plants.

  17. Verborgen carrières; oudere kunstenaars en een leven lang leren : een narratief PhD-onderzoek naar levenslang en levensbreed leren binnen de gevorderde beroepspraktijk van beeldende kunstenaars

    NARCIS (Netherlands)

    Delfgaauw, Leo

    2014-01-01

    Oudere Kunstenaars en een leven lang leren. ​Verborgen carrières: oudere kunstenaars en een leven lang leren. Een narratief-biografisch onderzoek naar levenslang en levensbreed leren binnen de gevorderde beroepspraktijk van beeldende kunstenaars. PhD-research Leo Delfgaauw. Promotoren: prof. dr.

  18. Organization of nuclear regulatory activities

    International Nuclear Information System (INIS)

    Blidaru, Valentin

    2008-01-01

    facilities; - Accident analyses; - Criticality calculations; - Licensing process for TRIGA research reactor; - Application of RESP code for CANDU type power reactors. The main tasks, objectives and methodologies applied by the Regulatory Authority are presented. The main nuclear facilities to which specific regulatory approaches are applied are: - Cernavoda Nuclear Power Plant Unit 1; - Cernavoda NPP Unit 2; - TRIGA Research reactor; - WWR-S research reactor (in conservation); - Specific installations related to the nuclear safety area of licensing, namely; - devices as C-2, C-5, C-6, by the TRIGA research reactor; - criticality aspects relating to transportation and storage of the fresh and spent fuels; - CANDU6 fuel plant; - dry storage facilities for spent fuel. The second half of the paper deals with specific aspects concerning the TRIGA research reactors. There are described the regulatory approaches and the licensing process, it is given a presentation of the configuration of the reactor, the operation of replacing the HEU fuel by LEU fuel, operation and applications of the reactor and finally specific aspects of the licensing process. These aspects concern the following issues: - reactivity accidents; - core interaction; - fuel temperature; prompt negative temperature coefficient. The regulatory approach for further licensing process deals with the following aspects: - nuclear safety documentation assessment for the reactor and each experimental device; - the operational licence to be issued for the whole nuclear unit; - technical nuclear safety documentation to be revised by the licensee and additional safety assessment to be performed for the reactor itself and also for the experimental devices in order to establish the concordance with the design changes (conversion to LEU from HEU fuel, 6 control rods in the reactor control system); - technical limits and conditions to be well established according to the tests conclusions or independent calculations and safety

  19. Regulatory guidance document

    International Nuclear Information System (INIS)

    1994-05-01

    The Office of Civilian Radioactive Waste Management (OCRWM) Program Management System Manual requires preparation of the OCRWM Regulatory Guidance Document (RGD) that addresses licensing, environmental compliance, and safety and health compliance. The document provides: regulatory compliance policy; guidance to OCRWM organizational elements to ensure a consistent approach when complying with regulatory requirements; strategies to achieve policy objectives; organizational responsibilities for regulatory compliance; guidance with regard to Program compliance oversight; and guidance on the contents of a project-level Regulatory Compliance Plan. The scope of the RGD includes site suitability evaluation, licensing, environmental compliance, and safety and health compliance, in accordance with the direction provided by Section 4.6.3 of the PMS Manual. Site suitability evaluation and regulatory compliance during site characterization are significant activities, particularly with regard to the YW MSA. OCRWM's evaluation of whether the Yucca Mountain site is suitable for repository development must precede its submittal of a license application to the Nuclear Regulatory Commission (NRC). Accordingly, site suitability evaluation is discussed in Chapter 4, and the general statements of policy regarding site suitability evaluation are discussed in Section 2.1. Although much of the data and analyses may initially be similar, the licensing process is discussed separately in Chapter 5. Environmental compliance is discussed in Chapter 6. Safety and Health compliance is discussed in Chapter 7

  20. Energy and climate hand-in-hand: Financing RES-E support with carbon revenues

    International Nuclear Information System (INIS)

    Verde, Stefano F.; Pazienza, Maria Grazia

    2016-01-01

    In Italy, the cost of support for renewable electricity (RES-E) is largely recovered through the “A3 surcharge”, which weighs heavily on electricity bills. Using household survey data, we show the A3 surcharge is markedly regressive. Carbon taxation in the non-ETS sector is envisaged as a means to reduce CO_2 emissions cost-effectively and generate revenue to lower the A3 surcharge. A non-ETS carbon tax would be less regressive than the A3 surcharge and its cost would be more evenly distributed across households. We calculate the revenue of a €20/tCO_2 non-ETS carbon tax would have allowed a cut in the A3 surcharge of about 68% in 2011, and 39% in 2012. The impact of the carbon tax plus the reduced A3 surcharge would have been less regressive, but the cost higher for most households. The restrictions imposed in the simulations mean the results are only appropriate to render first-round effects of the reform. Policy relevance: In the vast majority of the EU Member States, the cost of RES-E support is largely paid by electricity consumers, most often through specific surcharges. Rising electricity prices are a common concern given the implications for competitiveness and equity. The Member States facing this issue could conveniently address it through environmental tax reforms consistent with the Climate and Energy Package. Replacing RES-E surcharges with carbon taxes in the non-ETS sector would permit cost-effective reduction of CO_2 emissions while allocating the cost of RES-E support more equitably. The difference in regressivity would stem from the different consumption patterns of home fuels (including electricity) and motor fuels across income distribution. A cross-country comparison of energy household budget shares proves the structural nature of this difference between home fuels and motor fuels. Moreover, the notion that electricity consumers should pay for RES-E support is questioned on the grounds that electricity is a basic necessity good and RES

  1. Managing Regulatory Body Competence

    International Nuclear Information System (INIS)

    2013-01-01

    In 2001, the IAEA published TECDOC 1254, which examined the way in which the recognized functions of a regulatory body for nuclear facilities results in competence needs. Using the systematic approach to training (SAT), TECDOC 1254 provided a framework for regulatory bodies for managing training and developing and their maintaining their competence. It has been successfully used by many regulators. The IAEA has also introduced a methodology and an assessment tool - Guidelines for Systematic Assessment of Regulatory Competence Needs (SARCoN) - which provides practical guidance on analysing the training and development needs of a regulatory body and, through a gap analysis, guidance on establishing competence needs and how to meet them. In 2009, the IAEA established a steering committee (supported by a bureau) with the mission to advise the IAEA on how it could best assist Member States to develop suitable competence management systems for their regulatory bodies. The committee recommended the development of a safety report on managing staff competence as an integral part of a regulatory body's management system. This Safety Report was developed in response to this request. It supersedes TECDOC 1254, broadens its application to regulatory bodies for all facilities and activities, and builds upon the experience gained through the application of TECDOC 1254 and SARCoN and the feedback received from Member States. This Safety Report applies to the management of adequate competence as needs change, and as such is equally applicable to the needs of States 'embarking' on a nuclear power programme. It also deals with the special case of building up the competence of regulatory bodies as part of the overall process of establishing an 'embarking' State's regulatory system

  2. kmer-SVM: a web server for identifying predictive regulatory sequence features in genomic data sets

    Science.gov (United States)

    Fletez-Brant, Christopher; Lee, Dongwon; McCallion, Andrew S.; Beer, Michael A.

    2013-01-01

    Massively parallel sequencing technologies have made the generation of genomic data sets a routine component of many biological investigations. For example, Chromatin immunoprecipitation followed by sequence assays detect genomic regions bound (directly or indirectly) by specific factors, and DNase-seq identifies regions of open chromatin. A major bottleneck in the interpretation of these data is the identification of the underlying DNA sequence code that defines, and ultimately facilitates prediction of, these transcription factor (TF) bound or open chromatin regions. We have recently developed a novel computational methodology, which uses a support vector machine (SVM) with kmer sequence features (kmer-SVM) to identify predictive combinations of short transcription factor-binding sites, which determine the tissue specificity of these genomic assays (Lee, Karchin and Beer, Discriminative prediction of mammalian enhancers from DNA sequence. Genome Res. 2011; 21:2167–80). This regulatory information can (i) give confidence in genomic experiments by recovering previously known binding sites, and (ii) reveal novel sequence features for subsequent experimental testing of cooperative mechanisms. Here, we describe the development and implementation of a web server to allow the broader research community to independently apply our kmer-SVM to analyze and interpret their genomic datasets. We analyze five recently published data sets and demonstrate how this tool identifies accessory factors and repressive sequence elements. kmer-SVM is available at http://kmersvm.beerlab.org. PMID:23771147

  3. Regulatory Improvements for Effective Integration of Distributed Generation into Electricity Distribution Networks

    International Nuclear Information System (INIS)

    Scheepers, M.J.J.; Jansen, J.C.; De Joode, J.; Bauknecht, D.; Gomez, T.; Pudjianto, D.; Strbac, G.; Ropenus, S.

    2007-11-01

    The growth of distributed electricity supply of renewable energy sources (RES-E) and combined heat and power (CHP) - so called distributed generation (DG) - can cause technical problems for electricity distribution networks. These integration problems can be overcome by reinforcing the network. Many European Member States apply network regulation that does not account for the impact of DG growth on the network costs. Passing on network integration costs to the DG-operator who is responsible for these extra costs may result in discrimination between different DG plants and between DG and large power generation. Therefore, in many regulatory systems distribution system operators (DSOs) are not being compensated for the DG integration costs. The DG-GRID project analysed technical and economical barriers for integration of distributed generation into electricity distribution networks. The project looked into the impact of a high DG deployment on the electricity distribution system costs and the impact on the financial position of the DSO. Several ways for improving network regulation in order to compensate DSOs for the increasing DG penetration were identified and tested. The DG-GRID project looked also into stimulating network innovations through economic regulation. The project was co-financed by the European Commission and carried out by nine European universities and research institutes. This report summarises the project results and is based on a number of DG-GRID reports that describe the conducted analyses and their results

  4. Full Len gth Res earc h Arti cle Full Length Research Article

    African Journals Online (AJOL)

    functioning of adults as well as children, often with significant ... learning disability particularly in children (Albert,. 1999 ... Signs and Symptoms of this infection include, mild to ..... Isolation and Antimicrobial ... Bayesian Statistics for Social.

  5. ResDAC - Intro to the Use of Medicare Data for Research

    Data.gov (United States)

    U.S. Department of Health & Human Services — This brief presentation outlines the educational objectives for the Introduction to Medicare workshop. Objectives of the workshop which are found in the various...

  6. 77 FR 8020 - Semiannual Regulatory Agenda

    Science.gov (United States)

    2012-02-13

    ... (Reg Plan Seq No. 148). 452 Small Business Innovation 3245-AF84 Research (SBIR) Program Policy... Business Innovation Research (SBIR) Program Policy Directive Regulatory Plan: This entry is Seq. No. 149 in... proposal for a contract and that if the percentage is not met, the large business prime contractor must...

  7. ABSTRACTS: HortFlora Res. Spectrum, Vol. 4, 2015

    OpenAIRE

    Umrao, Dr. V.K.

    2017-01-01

    The HortFlora Research Spectrum (HRS), Website: www.hortflorajournal.com, is an international-peer reviewed, open access journal that serves as a forum for the exchange and dissemination of R & D advances and innovations in all facets of Horticultural Science (Pomology, Olericulture, Floriculture, Post Harvest Technology, Plant Biotechnology, and Medicinal & Aromatic Plants etc.) and its allied branches on an international level. HRS is officially published quarterly (March, June, Septemb...

  8. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Joseph Daniels1,&, Ruth Nduati1,2, James Kiarie1,3, Carey Farquhar1,4,5 .... or basic science research career (Socio-Behavioral Research, .... a research environment that supports knowledge sharing to develop research ...

  9. NRC regulatory agenda

    International Nuclear Information System (INIS)

    1990-10-01

    The Regulatory Agenda is a quarterly compilation of all rules on which the NRC has recently completed action or has proposed, or is considering action and of all petitions for rulemaking that the NRC has received that are pending disposition

  10. NRC regulatory agenda

    International Nuclear Information System (INIS)

    1990-04-01

    The Regulatory Agenda is a quarterly compilation of all rules on which the NRC has recently completed action or has proposed, or is considering action and of all petitions for rulemaking that the NRC has received that are pending disposition

  11. Through the regulatory hoop

    International Nuclear Information System (INIS)

    Kirner, N.P.

    1985-01-01

    There are many regulatory hoops through which waste generators, brokers, and disposal site operators must jump to dispose of waste safely. As the proposed exclusionary date of January 1, 1986, approaches, these regulatory hoops have the distinct possibility of multiplying or at least changing shape. The state of Washington, in its role as an Agreement State with the US Nuclear Regulatory Commission, licenses and inspects the commercial operator of the Northwest Compact's low-level radioactive waste disposal site on the Hanford Reservation. Washington has received as much as 53%, or 1.4 million cubic feet per year, of the nation's total volume of waste disposed. To control such a large volume of waste, a regulatory program involving six agencies has developed over the years in Washington

  12. Quarterly technical progress report on water reactor safety programs sponsored by the Nuclear Regulatory Commission's Division of Reactor Safety Research, October--December 1976

    International Nuclear Information System (INIS)

    Ferguson, J.B.

    1977-04-01

    Light water reactor safety research performed October through December 1976 is discussed. An analysis to determine the effect of emergency core coolant (ECC) injection location and pump speed on system response characteristics was performed. An analysis to evaluate the capability of commonly used critical heat flux (CHF) correlations to calculate the time of the first CHF in the Semiscale core during a loss-of-coolant experiment (LOCE) was performed. A test program and study to determine the effect thermocouples mounted on the outside fuel rod surfaces would have on the departure from nucleate boiling (DNB) phenomena in the LOFT core during steady state operation were completed. A correlation for use in predicting DNB heat fluxes in the LOFT core was developed. Tests of an experimental transit time flowmeter were completed. A nuclear test was performed to obtain fuel rod behavior data from four PWR-type rods during film boiling operation representative of PWR conditions. Preliminary results from the postirradiation examination of Test IE-1 fuel rods are given. Results of Irradiation Effects Tests IE-2 and IE-3 are given. Gap Conductance Test GC 2-1 was performed to evaluate the effects of fuel density, initial gap width, and fill gas composition on the pellet-cladding gap conductance

  13. Quarterly technical progress report on water reactor safety programs sponsored by the Nuclear Regulatory Commission's Division of Reactor Safety Research, October--December 1976

    Energy Technology Data Exchange (ETDEWEB)

    Ferguson, J. B. [ed.

    1977-04-01

    Light water reactor safety research performed October through December 1976 is discussed. An analysis to determine the effect of emergency core coolant (ECC) injection location and pump speed on system response characteristics was performed. An analysis to evaluate the capability of commonly used critical heat flux (CHF) correlations to calculate the time of the first CHF in the Semiscale core during a loss-of-coolant experiment (LOCE) was performed. A test program and study to determine the effect thermocouples mounted on the outside fuel rod surfaces would have on the departure from nucleate boiling (DNB) phenomena in the LOFT core during steady state operation were completed. A correlation for use in predicting DNB heat fluxes in the LOFT core was developed. Tests of an experimental transit time flowmeter were completed. A nuclear test was performed to obtain fuel rod behavior data from four PWR-type rods during film boiling operation representative of PWR conditions. Preliminary results from the postirradiation examination of Test IE-1 fuel rods are given. Results of Irradiation Effects Tests IE-2 and IE-3 are given. Gap Conductance Test GC 2-1 was performed to evaluate the effects of fuel density, initial gap width, and fill gas composition on the pellet-cladding gap conductance.

  14. Quarterly technical progress report on water reactor safety programs sponsored by the Nuclear Regulatory Commission's Division of Reactor Safety Research, January--March 1976

    Energy Technology Data Exchange (ETDEWEB)

    Zane, J. O.; Farman, R. F.; Hanson, D. J.; Peterson, A. C.; Ybarrondo, L. J.; Berta, V. T.; Naff, S. A.; Crocker, J. G.; Martinson, Z. R.; Smolik, G. R.; Cawood, G. W.; Quapp, W. J.; Ramsthaler, J. H.; Ransom, V. H.; Scofield, M. P.; Dearien, J. A.; Bohn, M. P.; Burnham, B. W.; James, S. W.; Lee, W. H.; Lime, J. F.; Nalezny, C. L.; MacDonald, P. E.; Thompson, L. B.; Domenico, W. F.; Rice, R. E.; Hendrix, C. E.; Davis, C. B.

    1976-06-01

    Light water reactor sfaety research performed January through March 1976 is summarized. Results of the Semiscale Mod-1 blowdown heat transfer test series relating to those phenomena that influence core fluid and heat transfer effects are analyzed, and preliminary analyses of the recently completed reflood heat transfer test series are summarized for the forced and gravity feed reflood tests. The first nonnuclear LOCE in the LOFT program was successfully completed and preliminary results are presented. Preliminary results are given for the PCM 8-1 RF Test, the PCM-2A Test, and the Irradiation Effects Scoping Test 2 in the Thermal Fuel Behavior Program. Model development and verification efforts reported in the Reactor Behavior Program include checkout of RELAP4/MOD5 Update 1, development of a new hydrodynamic model for two-phase separated flows, development of the RACHET code to assess the assumptions in current fuel behavior codes of uniform stress and strain in the cladding, modifications of the containment code BEACON, analysis of results from the Halden Assembly IFA-429 helium sorption experiment, development of correlations for the thermal conductivity of UO/sub 2/ and (U,Pu)O/sub 2/, and evaluation of RALAP4 through comparison of calculated results with data from the GE Blowdown Heat Transfer and Semiscale experiments.

  15. Annual report to the Atomic Energy Control Board on the regulatory research and support program April 1, 1993 - March 31, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    This report presents information on the scope of RSP activities during the year and describes how the program was managed, organized and implemented. Overviews are presented of research and support work undertaken in each field of activity and some highlights of results obtained and included. More detailed information has been compiled into six appendices which are being issued as a separate document. The membership of active review panels is given in Appendix A. Appendix B contains summary descriptions and information on the status of individual projects. Appendix C presents a list of those projects which were within the overall RSP but were not active during the year. Appendix D lists the projects which were complete but for which the post project evaluation had as yet to be completed. All projects which were worked on during the year are listed in Appendix E. Specific objectives set for the RSP for Fiscal Year 1993/94 and the degree to which the objectives were achieved are outlined in Appendix F. 3 tabs.

  16. Annual report to the Atomic Energy Control Board on the regulatory research and support program April 1, 1993 - March 31, 1994

    International Nuclear Information System (INIS)

    1995-05-01

    This report presents information on the scope of RSP activities during the year and describes how the program was managed, organized and implemented. Overviews are presented of research and support work undertaken in each field of activity and some highlights of results obtained and included. More detailed information has been compiled into six appendices which are being issued as a separate document. The membership of active review panels is given in Appendix A. Appendix B contains summary descriptions and information on the status of individual projects. Appendix C presents a list of those projects which were within the overall RSP but were not active during the year. Appendix D lists the projects which were complete but for which the post project evaluation had as yet to be completed. All projects which were worked on during the year are listed in Appendix E. Specific objectives set for the RSP for Fiscal Year 1993/94 and the degree to which the objectives were achieved are outlined in Appendix F. 3 tabs

  17. Electronic and optoelectronic device applications based on ReS2

    Science.gov (United States)

    Liu, Erfu; Long, Mingsheng; Wang, Yaojia; Pan, Yiming; Ho, Chinghwa; Wang, Baigeng; Miao, Feng

    Rhenium disulfide (ReS2) is a unique semiconducting TMD with distorted 1T structure and weak interlayer coupling. We have previously investigated its in-plane anisotropic property and electronic applications on FET and digital inverters. In this talk, we will present high responsivity phototransistors based on few-layer ReS2. Depending on the back gate voltage, source drain bias and incident optical light intensity, the maximum attainable photoresponsivity can reach as high as 88,600 A W-1, which is one of the highest value among individual two-dimensional materials with similar device structures. Such high photoresponsivity is attributed to the increased light absorption as well as the gain enhancement due to the existence of trap states in the few-layer ReS2 flakes. The existence of trap states is proved by temperature dependent transport measurements. It further enables the detection of weak signals. Our studies underscore ReS2 as a promising material for future electronic and sensitive optoelectronic applications.

  18. Modèles de gestion des ressources forestières du massif ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Expérimentation Participative et Adaptative de Modèles de Gestion des Ressources Forestières dans la Chaine Montagneuse de l'Atlas (Algérie, Maroc, Tunisie) : rapport final (17 mars 2009 au 18 septembre 2012). Download PDF. Reports. Unité de transformation de cire d'abeille (Commune de M'Sara). Download PDF ...

  19. Res, aliquid and nihil in Suárez and modern philosophy

    Directory of Open Access Journals (Sweden)

    Leopoldo Prieto López

    2013-07-01

    Full Text Available the main relevant philosophical aspect in Suárez’s interpretation of the transcendentals is his doctrine of the notions res and aliquid. therefore, after analyzing the nature and the number of the transcendentals, as well as the relationship between them and the first principles, the article goes into a detailed historical analysis of the notions res and aliquid. With precedents in Avicenna and Duns Scotus, the ens is understood according to Suarez, negatively, as it is not nothing and, in such sense, it is something (aliquid and, positively, as it has got a quidditas and, therefore, it is res. the question of nothing (nihil is thus introduced into modern metaphysics. What’s more, the said interpretation is one of the fundamental conditions of the transformation of metaphysics in modern ontology. thus, in the post- Cartesian context of Schulmetaphysik, and its aliquitas (as non-nihil and its quiditative character (as res being presumed, the ens will be understood as an intelligible. through that, a Copernican revolution commenced that anticipated Kant himself.

  20. Res Publica murrab läbi / Urmo Kübar

    Index Scriptorium Estoniae

    Kübar, Urmo, 1978-

    2004-01-01

    Ilmunud ka: Võta Võim : na russkom jazõke, 28. apr. 2004, lk. 1. 18. aprillil 2004 Tallinnas toimunud Res Publica valimiskonverentsist, kus kinnitati programm ja kandidaadid Euroopa Parlamendi valimisteks. Esinesid Urmas Reinsalu ja Juhan Parts. Vt. samas: Kust tuli 'Murrame läbi'?

  1. Res Publica alustas Tallinnas koostööd Keskerakonnaga / Siim Männik

    Index Scriptorium Estoniae

    Männik, Siim

    2005-01-01

    Ilmunud ka: Vabariik (venek.) 18. apr. lk. 2. Koalitsioonivahetusest Tallinnas. Linnavolikogu Res Publica fraktsiooni esimehe Andres Korgi, linnapea Tõnis Paltsi nõuniku Jaano Martin Otsa kommentaare. Tallinna linnapea hinnangul on sügisel koalitsiooni asudes seatud eesmärgid praeguseks peaaegu saavutatud

  2. Médecins Sans Frontières moves to protect refugee healthcare

    African Journals Online (AJOL)

    As Médecins Sans Frontières (MSF) spurned all European Union (EU) fund ing for its projects worldwide after a series of cynical EUcountry moves to choke inward refugee flow, South African. (SA) activists in Johannesburg this June protes ted the proposed stiffening of local refugee laws. The People's Coalition Against ...

  3. Dynamique de fréquentation des grands mammifères dans une ...

    African Journals Online (AJOL)

    SARAH

    31 juil. 2016 ... 2016 Dynamique de fréquentation des grands mammifères dans une clairière ... 2Ecole Régionale Post-Universitaire d'Aménagement et de gestion Intégrés des Forêts et ..... épidémiologique et contrôle des stomoxes à la.

  4. Distribution of costs induced by the integration of RES-E power

    International Nuclear Information System (INIS)

    Barth, Ruediger; Weber, Christoph; Swider, Derk J.

    2008-01-01

    This article focuses on the distribution of costs induced by the integration of electricity generation from renewable energy sources (RES-E). The treatment to distribute these costs on different market actors is crucial for its development. For this purpose, individual actors of electricity markets and several cost categories are identified. According to the defined cost structure, possible treatments to distribute the individual cost categories on different relevant actors are described. Finally, an evaluation of the cost distribution treatments based on an economic analysis is given. Economic efficiency recommends that clearly attributable (shallow) grid connection as well as (deep) grid costs are charged to the corresponding RES-E producer and that the RES-E producers are also charged the regulating power costs. However, deep grid integration costs should be updated to reflect evolving scarcities. Also regulating power costs should reflect actual scarcity and thus be symmetric and based on real-time prices, taking into account the overall system imbalance. Moreover, the time span between the closure of the spot market and actual delivery should be chosen as short as possible to enable accurate RES-E production forecasts

  5. Res-Parity: Parity Violation in Inelastic scattering at Low Q2

    International Nuclear Information System (INIS)

    Paul Reimer; Peter Bosted; John Arrington; Hamlet Mkrtchyan; Xiaochao Zheng

    2006-01-01

    Parity violating electron scattering has become a well established tool which has been used, for example, to probe the Standard Model and the strange-quark contribution to the nucleon. While much of this work has focused on elastic scattering, the RES-Parity experiment, which has been proposed to take place at Jefferson Laboratory, would focus on inelastic scattering in the low-Q 2 , low-W domain. RES-Parity would search for evidence of quark-hadron duality and resonance structure with parity violation in the resonance region. In terms of parity violation, this region is essentially unexplored, but the interpretation of other high-precision electron scattering experiments will rely on a reasonable understanding of scattering at lower energy and low-W through the effects of radiative corrections. RES-Parity would also study nuclear effects with the weak current. Because of the intrinsic broad band energy spectrum of neutrino beams, neutrino experiments are necessarily dependent on an untested, implicit assumption that these effects are identical to electromagnetic nuclear effects. RES-Parity is a relatively straight forward experiment. With a large expected asymmetry (∼ 0.5 x 10 -4 ) these studies may be completed with in a relatively brief period

  6. Taani ristisõjad Läänemere ääres / Linda Kaljundi

    Index Scriptorium Estoniae

    Kaljundi, Linda

    2007-01-01

    Raamatututvustus: Taani ristisõjad - sõda ja misjon Läänemere ääres / John H. Lind, Carsten Selch Jensen, Kurt Villads Jensen, Ane L. Bysted ; tõlkijad Ivar Rüütli ja Kalle Kroon ; teaduslik toimetaja ja järelsõna: Linda Kaljundi. Tallinn : Argo, 2007

  7. Proposta de um desenho da cadeia reversa para resíduos eletroeletrônicos

    Directory of Open Access Journals (Sweden)

    Reinaldo Alves de Sá Ferreira Júnior

    2016-12-01

    Full Text Available Com o crescimento da demanda dos equipamentos eletroeletrônicos e de sua rápida obsolescência, gera-se grande volume de resíduos, os quais possuem metais pesados altamente tóxicos, como o mercúrio, cobre, chumbo, arsênio, entre outros. A implantação da Logística Reversa (LR tem sido uma forma de gestão de grande sucesso, tanto no contexto internacional como nacional, e aliada a Politica Nacional de Resíduos Sólidos (PNRS tornou-se uma forma mais eficaz para o gerenciamento desses resíduos. Este artigo teve como objetivo, a partir da revisão na literatura referente à LR, PNRS e REEE apresentar atores, atribuições e processos associados, propondo, desta forma, uma estrutura geral para a cadeia de suprimentos reversa de pós-consumo associada aos REEE. A principal contribuição do artigo é proposição de um desenho da cadeia reversa para resíduos Eletroeletrônicos.

  8. Res Publica nõuab rea võimulubaduste täitmist / Rasmus Kagge

    Index Scriptorium Estoniae

    Kagge, Rasmus, 1977-

    2005-01-01

    Res Publica lubas koalitsioonipartneritele mitte minna koalitsioonileppe kallale, kui nad toetavad toppama jäänud lubaduste täitmist - haridusreformi, presidendi otsevalimiste seadustamist, riigikontrollile ka omavalitsuste kontrollimiseks õiguse andmist ja lapsevanema tulumaksuvaba miinimumi kahekordistamist alates pere teisest lapsest. Lisa: Võimuliitlaste soovid

  9. Aging research

    International Nuclear Information System (INIS)

    Ross, D.F. Jr.

    1988-01-01

    The USNRC Office of Nuclear Regulatory Research has developed a program for nuclear plant aging research (NPAR) to achieve an understanding of nuclear plant aging, its potential effects on safety, and methods for its detection and mitigation, sufficient for addressing safety and regulatory issues and supporting regulatory decisions on issues. Specifically, the NRC has aggressive research and regulatory programs associated with aging effects on piping, steam generators, containments, structures, and electrical and mechanical systems and components. In addition to safety assessment for the original license period for nuclear power plants, this aging information will be extremely useful in providing technical bases for efficient and effective regulation associated with possible license extension. This paper discusses the major activities of USNRC sponsored aging research program and recommends an approach to manage and handle aging at nuclear power plants

  10. Research

    African Journals Online (AJOL)

    A descriptive qualitative research design was used to determine whether participants ... simulation as a teaching method; a manikin offering effective learning; confidence ..... Tesch R. Qualitative Research: Analysis Types and Software Tools.

  11. Defining Tobacco Regulatory Science Competencies.

    Science.gov (United States)

    Wipfli, Heather L; Berman, Micah; Hanson, Kacey; Kelder, Steven; Solis, Amy; Villanti, Andrea C; Ribeiro, Carla M P; Meissner, Helen I; Anderson, Roger

    2017-02-01

    In 2013, the National Institutes of Health and the Food and Drug Administration funded a network of 14 Tobacco Centers of Regulatory Science (TCORS) with a mission that included research and training. A cross-TCORS Panel was established to define tobacco regulatory science (TRS) competencies to help harmonize and guide their emerging educational programs. The purpose of this paper is to describe the Panel's work to develop core TRS domains and competencies. The Panel developed the list of domains and competencies using a semistructured Delphi method divided into four phases occurring between November 2013 and August 2015. The final proposed list included a total of 51 competencies across six core domains and 28 competencies across five specialized domains. There is a need for continued discussion to establish the utility of the proposed set of competencies for emerging TRS curricula and to identify the best strategies for incorporating these competencies into TRS training programs. Given the field's broad multidisciplinary nature, further experience is needed to refine the core domains that should be covered in TRS training programs versus knowledge obtained in more specialized programs. Regulatory science to inform the regulation of tobacco products is an emerging field. The paper provides an initial list of core and specialized domains and competencies to be used in developing curricula for new and emerging training programs aimed at preparing a new cohort of scientists to conduct critical TRS research. © The Author 2016. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Res Publica soovib riigikogulaste kuluhüvitiste korra muutmist / Siim-Valmar Kiisler ; interv. Kalle Muuli

    Index Scriptorium Estoniae

    Kiisler, Siim, 1965-

    2003-01-01

    Res Publica saadikud teevad Riigikogu juhatusele ettepaneku muuta kuluhüvitiste korda, teatas intervjuus Res Publica saadikurühma esimees Siim-Valmar Kiisler. Kommenteerivad: Jaanus Männik, Toomas Varek. Vt. samas: Riigikogu liikmete vastuseid küsimustele tööga seotud kulude kohta: Robert Lepikson, Reet Roos, Janno Reiljan

  13. Experience of the Canary Islands in the development of insular 100% RES systems and micro-grids

    Energy Technology Data Exchange (ETDEWEB)

    Piernavieja, Gonzalo; Suarez, Salvador; Henriquez, Daniel [Instituto Tecnologico de Canarias (Canary Islands Institute of Technology - ITC), Las Palmas, Gran Canaria (Spain). RandD Div.

    2010-07-01

    Given the mentioned circumstances, conventional energy planning in the Canary Islands is a very complex task. The Regional Energy Plan PECAN (2007-2015) tries to correct the existing critical situation setting, among others, the ambitious goal of >25% electricity from RES (mostly wind) for 2015. In parallel to this conventional energy planning, outstanding initiatives in the distributed generation field are underway. ITC vision is that the Canarian Archipelago, given its particular characteristics (insular systems of different sizes, abundant RES potential -different sources-, important natural and biodiversity heritage, etc.), are a laboratory for testing and demonstrating new energy technologies in real conditions, as well as their commercial implementation. These new technologies include energy storage (particularly for excess RES that cannot be absorbed by the grids), development of 100% energy self- sufficiency models (with exclusive use of RES) and micro-/minigrids with high RES penetration and RES forecasting, including advanced ICTs and sustainable mobility concepts (e.g. V2G technologies). Given the high conventional generation costs and the relatively low RES costs (wind electricity production cost is less than 0.03 Euro/kWh), the Canary Islands could in the short term achieve grid parity, and in this sense pioneer the change to a RES based energy system. Models tested on the islands could be exported or extrapolated to our islands, regions of developing countries and even other regions in continental Europe. (orig.)

  14. Analüütikud ennustavad Res Publicale mõõnast pääsu / Rasmus Kagge

    Index Scriptorium Estoniae

    Kagge, Rasmus, 1977-

    2005-01-01

    Poliitikavaatlejate hinnangul ületab Res Publica mõõna ja saab järgmistel parlamendivalimistel kuni 12 kohta, kui nad loobuvad "uue poliitika" stiilis loosungitest ja kõrkusest. Lisa: Mõõna põhjusi. Vt. samas: Taavi Veskimägi lubas lõpetada Res Publica peataoleku

  15. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  16. Institutional review board and regulatory solutions in the dental PBRN

    DEFF Research Database (Denmark)

    Gilbert, Gregg H; Qvist, Vibeke; Moore, Sheila D

    2010-01-01

    Effectively addressing regulatory and human participant protection issues with Institutional Review Boards (IRBs, or ethics committees) and grants administration entities is an important component of conducting research in large collaborative networks. A dental practice-based research network...

  17. Perceptions of regulatory approaches

    International Nuclear Information System (INIS)

    Halin, Magnus; Leinonen, Ruusaliisa

    2012-01-01

    Ms. Ruusaliisa Leinonen and Mr. Magnus Halin from Fortum gave a joint presentation on industry perceptions of regulatory oversight of LMfS/SC. It was concluded that an open culture of discussion exists between the regulator (STUK) and the licensee, based on the common goal of nuclear safety. An example was provided of on how regulatory interventions helped foster improvements to individual and collective dose rate trends, which had remained static. Regulatory interventions included discussions on the ALARA concept to reinforce the requirement to continuously strive for improvements in safety performance. Safety culture has also been built into regulatory inspections in recent years. Training days have also been organised by the regulatory body to help develop a shared understanding of safety culture between licensee and regulatory personnel. Fortum has also developed their own training for managers and supervisors. Training and ongoing discussion on LMfS/SC safety culture is considered particularly important because both Fortum and the regulatory body are experiencing an influx of new staff due to the demographic profile of their organisations. It was noted that further work is needed to reach a common understanding of safety culture on a practical level (e.g., for a mechanic setting to work), and in relation to the inspection criteria used by the regulator. The challenges associated with companies with a mix of energy types were also discussed. This can make it more difficult to understand responsibilities and decision making processes, including the role of the parent body organisation. It also makes communication more challenging due to increased complexity and a larger number of stakeholders

  18. Typologie et dynamique forestières: Un exemple en Barousse (Hautes Pyrénées

    Directory of Open Access Journals (Sweden)

    Mazars, Jacqueline

    1996-12-01

    Full Text Available An ecological analysis of the Pyrenean beech groves (Barousse points to hydric conditions as the main factor determining different ecological units on a same geological substratum. This approach, completed by the historical research that brings to light the manmade actions in the fir elimination of this area, can in part generate the knowledge of the real potential forestry (Fir-Beech, Fir. The structural analysis of stands, disturbed in the past by overexploitation, indicates that the upper stratum has closed, and that, often through pioneer phases, these woods have extended their area.

    [fr] L'analyse phytoécologique de hêtraies des Pyrénées Centrales (Barousse montre que ce sont surtout les variations des conditions hydriques qui déterminent, sur un même substrat colluvial, les différentes unités stationnelles observées. Cette approche, complétée par des études historiques 'mettant en lumière le déterminisme anthropique de la disparition presque totale du Sapin de cette région, permet, en partie, de connaître les potentialités forestières réelles (hêtraiesapinière, sapinière. L'analyse structurale des peuplements, anciennement ouverts par surexploitation, indique une fermeture généralisée du couvert et une dynamique d'extension de ces formations souvent par l'intermédiaire de phases pionnières.

  19. Prédiction du comportement à long terme des matériaux polymères

    Science.gov (United States)

    Lemaire, J.

    1998-06-01

    Most of the world activity on research, development and control of polymer durability is still based on empirical techniques developed in the early ages of polymer uses. Those techniques should be critically analysed considering the state of the art in the fundamental understanding of these complex phenomena. A more rational approach is described, especially to predict the lifetime of polymeric materials in environmental conditions. That approach is based on the recognition of the chemical evolution mechanisms. Les activités de recherche, développement et contrôle de durabilité des matériaux polymères sont encore, pour une part très importante, basées sur l'emploi de techniques empiriques dont les principes ont été énoncés dès le début de l'exploitation de ces matériaux. Une analyse critique de ces méthodes s'impose aujourd'hui en tenant compte de l'avancement des connaissances. Une approche plus rationnelle est décrite, approche basée sur la reconnaissance des mécanismes d'évolution chimique. A titre d'exemple, le mécanisme d'évolution du PVC sous contraintes conjuguées de l'UV, de la chaleur et de l'oxygène, est décrit. Des études récentes de photooxydation de polymères conducteurs au sein de polyéthylène sont également succinctement rapportées.

  20. Copépodes, Cladocères et Rotifères du lac Sidi M'hamed Benali (Algérie Nord-Occidentale

    Directory of Open Access Journals (Sweden)

    Mohamed Ali Bouzidi

    2010-03-01

    Full Text Available En 2008, 33 espèces de Cladocères, Copépodes et Rotifères ont été observées dans le lac Sidi M'hamed Benali (contre 12 seulement en 1992.Les Copépodes dominent en mars, avril, juillet, août et septembre, avec respectivement des dominances (Do égales à : 56,6 %, 55,0 %, 55,0 %, 46,4 % et 90,0 %. Les Cladocères dominent en février (Do = 37,2 %, mai (Do = 47,4 % et décembre (Do = 48,6 %. Les Rotifères sont extrêmement abondants et présentent une large dominance en janvier (Do = 95,3 %. La population zooplanctonique est très faible en juillet et en août. Au cours de l'année le peuplement varie en fonction de la température, des conditions hydrologiques, de l'abondance de la nourriture et de la prédation par les poissons.In 2008, 33 species of Cladocers, Copepods and Rotifers have been observed in Sidi M’hamed Benali Lake (against only 12 species in 1992. The Copepods dominate in March, April, July, August and September, respectively with dominance (Do equal to 56.6 %, 55.0 %, 55.0 %, 46.4 % and 90.0 %. Cladocers dominated in February (Do = 37.2 %, May (Do = 47.4 % and December (Do = 48.6 %. The rotifers are extremely abundant and have a wide dominance in January (Do = 95.3%. The zooplankton population is very low in July and August. During the year, the population varies with temperature, water conditions, abundance of food and predation by fishes.

  1. Les manières de salle de garde, un patrimoine menacé

    Directory of Open Access Journals (Sweden)

    Docteur Emmanuelle Godeau

    2011-12-01

    Full Text Available La recherche sur laquelle repose cet article analyse la place des coutumes des marges de l’apprentissage universitaire dans la construction du personnage du médecin spécialiste français, dans lequel l’internat et les manières à y apprendre sont centrales. Environ cent entretiens ethnographiques avec des spécialistes d’âges et d’exercices variés ont été menés. L’internat concerne les futurs spécialistes, reçus au concours de l’internat qui donne accès, après 6 années d’étude communes à tous les médecins, à une formation propre de 4-6 années supplémentaires, pendant laquelle ils apprennent non seulement leur profession auprès de malades et de patrons, mais aussi les manières constitutives du personnage du spécialiste, en fréquentant internes et internats. Chaque midi à table, les internes acquièrent ces manières de salle de garde. À travers l’apprentissage de règles contraignantes et souvent paradoxales, de savoir-dire et de savoir-faire, autrement dit de savoir-être propres au groupe, ils vont acquérir une compétence spécifique : nouveau calendrier, nouvelle langue, nouveau code comportemental, nouvelle hiérarchie, nouveaux devoirs… dont le non-respect est sanctionné par des gages codifiés. La mise en place de rituels collectifs fondant la communauté, l’application de codes précis, la valorisation de modèles identificatoires permettent à chacun de prendre place, de s’impliquer selon une organisation concentrique, de donner sens aux expériences en cours en les intégrant dans une logique initiatique. Cet apprentissage se singularise par le fait qu’il coexiste avec celui d’un langage médical parfois complexe, d’attitudes professionnelles codifiées, d’un sens de la hiérarchie aiguisé, d’un code de déontologie rigoureux… autant de caractéristiques propres au monde hospitalo-universitaire.This paper is based on a research on the importance of customs learned in the

  2. Nuclear regulatory decision making

    International Nuclear Information System (INIS)

    2005-01-01

    The fundamental objective of all nuclear safety regulatory bodies is to ensure that nuclear utilities operate their plants at all times in an acceptably safe manner. In meeting this objective, the regulatory body should strive to ensure that its regulatory decisions are technically sound, consistent from case to case, and timely. In addition, the regulator must be aware that its decisions and the circumstances surrounding those decisions can affect how its stakeholders, such as government policy makers, the industry it regulates, and the public, view it as an effective and credible regulator. In order to maintain the confidence of those stakeholders, the regulator should make sure that its decisions are transparent, have a clear basis in law and regulations, and are seen by impartial observers to be fair to all parties. Based on the work of a Nuclear Energy Agency (NEA) expert group, this report discusses some of the basic principles and criteria that a regulatory body should consider in making decisions and describes the elements of an integrated framework for regulatory decision making. (author)

  3. Knowledge Translation to Advance the Nurse Practitioner Role in British Columbia: Researchers and decision-makers conduct policy-relevant research to guide legislative and regulatory development and the design of a nurse practitioner education program.

    OpenAIRE

    MacDonald, Marjorie; Regan, Sandra; Davidson, Heather; Schreiber, Rita; Crickmore, Jane; Moss, Lesley; Pinelli, Janet; Pauly, Bernadette

    2006-01-01

    This project brought together a team of researchers and decision-makers to conduct policy-relevant research to support the introduction of advanced nursing practice roles in British Columbia. All team members, including decision-makers, were actively involved in the conceptualization, design, data collection, analysis and interpretation of the study. This level of engagement, coupled with ongoing knowledge translation (KT) activities, led to the implementation by stakeholders of a majority of...

  4. Development of multipurpose regulatory PSA model

    International Nuclear Information System (INIS)

    Lee, Chang Ju; Sung, Key Yong; Kim, Hho Jung; Yang, Joon Eon; Ha, Jae Joo

    2004-01-01

    Generally, risk information for nuclear facilities comes from the results of Probabilistic safety assessment (PSA). PSA is a systematic tool to ensure the safety of nuclear facilities, since it is based on thorough and consistent application of probability models. In particular, the PSA has been widely utilized for risk-informed regulation (RIR), including various licensee-initiated risk-informed applications (RIA). In any regulatory decision, the main goal is to make a sound safety decision based on technically defensible information. Also, due to the increased public requests for giving a safety guarantee, the regulator should provide the visible means of safety. The use of PSA by the regulator can give the answer on this problem. Therefore, in order to study the applicability of risk information for regulatory safety management, it is a demanding task to prepare a well-established regulatory PSA model and tool. In 2002, KINS and KAERI together made a research cooperation to form a working group to develop the regulatory PSA model - so-called MPAS model. The MPAS stands for multipurpose probabilistic analysis of safety. For instance, a role of the MPAS model is to give some risk insights in the preparation of various regulatory programs. Another role of this model is to provide an independent risk information to the regulator during regulatory decision-making, not depending on the licensee's information

  5. Impact of regulatory science on global public health

    OpenAIRE

    Meghal Patel; Margaret Ann Miller

    2012-01-01

    Regulatory science plays a vital role in protecting and promoting global public health by providing the scientific basis for ensuring that food and medical products are safe, properly labeled, and effective. Regulatory science research was first developed for the determination of product safety in the early part of the 20th Century, and continues to support innovation of the processes needed for regulatory policy decisions. Historically, public health laws and regulations were enacted followi...

  6. Policy and Regulatory Roadmaps for the Integration of Distributed Generation and the Development of Sustainable Electricity Networks. Final Report of the SUSTELNET project

    International Nuclear Information System (INIS)

    Scheepers, M.J.J.

    2004-08-01

    The SUSTELNET project has been created to identify criteria for a regulatory framework for future electricity markets and network structures that create a level playing field between centralised and decentralised generation and facilitate the integration of renewable energy sources (RES). Furthermore, the objective of the project was to develop regulatory roadmaps for the transition to a sustainable electricity market and network structure. This report summarizes the results of the project. These results consist of: criteria, guidelines and rationales for a future electricity policy and regulatory framework, an outline for the development of regulatory roadmaps and nine national regulatory roadmaps (for Denmark, Germany, Italy, the Netherlands, United Kingdom, Czech Republic, Poland, Hungary and Slovakia), recommendations for a European regulatory policy on distributed generation and a benchmark study of current Member States policies towards distributed generation

  7. Mission Risk Reduction Regulatory Change Management

    Science.gov (United States)

    Scroggins, Sharon

    2007-01-01

    NASA Headquarters Environmental Management Division supports NASA's mission to pioneer the future in space exploration, scientific discovery, and aeronautics research by integrating environmental considerations into programs and projects early-on, thereby proactively reducing NASA's exposure to institutional, programmatic and operational risk. As part of this effort, NASA established the Principal Center for Regulatory Risk Analysis and Communication (RRAC PC) as a resource for detecting, analyzing, and communicating environmental regulatory risks to the NASA stakeholder community. The RRAC PC focuses on detecting emerging environmental regulations and other operational change drivers that may pose risks to NASA programs and facilities, and effectively communicating the potential risks. For example, regulatory change may restrict how and where certain activities or operations may be conducted. Regulatory change can also directly affect the ability to use certain materials by mandating a production phase-out or restricting usage applications of certain materials. Regulatory change can result in significant adverse impacts to NASA programs and facilities due to NASA's stringent performance requirements for materials and components related to human-rated space vehicles. Even if a regulation does not directly affect NASA operations, U.S. and international regulations can pose program risks indirectly through requirements levied on manufacturers and vendors of components and materials. For example, manufacturers can change their formulations to comply with new regulatory requirements. Such changes can require time-consuming and costly requalification certification for use in human spaceflight programs. The RRAC PC has implemented a system for proactively managing regulatory change to minimize potential adverse impacts to NASA programs and facilities. This presentation highlights the process utilized by the RRACPC to communicate regulatory change and the associated

  8. Estudo da durabilidade de argamassas alternativas contendo resíduos Durability study of alternative mortars containing wastes

    Directory of Open Access Journals (Sweden)

    J. Farias Filho

    2011-12-01

    Full Text Available O interesse pela preservação dos recursos naturais e a busca pelo desenvolvimento sustentável tem despertado interesse de um grande número de pesquisadores visando obter materiais de construção não convencionais. Dentre essas possibilidades, destacam-se os resíduos produzidos pela construção civil e pela indústria de beneficiamento de granito, em virtude do volume gerado e os impactos ambientais do seu descarte inadequado. Este trabalho tem como objetivo estudar a durabilidade das argamassas alternativas incorporadas com resíduos de construção civil e da serragem do granito. Para quantificar a durabilidade dos materiais estudados, foram realizados ensaios de envelhecimento natural e ensaios de envelhecimento acelerado através de ciclos de molhagem e secagem, visando simular condições de utilização e avaliar sua degradação. Nos estudos da durabilidade foram utilizados traços de argamassas para alvenaria de elevação, com percentagens de substituição, em peso, da cal por resíduo de 30% e 50%. Os resultados para o envelhecimento natural evidenciaram o comprometimento da durabilidade do material após 60 dias com redução no comportamento mecânico, sendo os melhores resultados para os corpos-de-prova com 30% e 50% de resíduo de construção. No envelhecimento acelerado, para os tratamentos adotados, os resultados evidenciaram a ação da formação de silicoaluminatos de cálcio e potássio que favoreceram um aumento do comportamento mecânico e, além disso, não foi observado o comprometimento da sua durabilidade.The preservation of natural resources and search for sustainable development are increase in interest by the researchers with the aim to obtain knowledge of non conventional materials. Among these possibilities stand out the recycling of residues from civil construction and from granite industry, which are producers of large amount of residues and causing great environmental impacts. The aim of this work is to

  9. Nuclear Regulatory Legislation

    International Nuclear Information System (INIS)

    1989-08-01

    This compilation of statutes and material pertaining to nuclear regulatory legislation through the 100th Congress, 2nd Session, has been prepared by the Office of the General Counsel, US Nuclear Regulatory Commission, with the assistance of staff, for use as an internal resource document. Persons using this document are placed on notice that it may not be used as an authoritative citation in lieu of the primary legislative sources. Furthermore, while every effort has been made to ensure the completeness and accuracy of this material, neither the United States Government, the Nuclear Regulatory Commission, nor any of their employees makes any expressed or implied warranty or assumes liability for the accuracy or completeness of the material presented in this compilation

  10. Regulatory and licensee surveys

    International Nuclear Information System (INIS)

    2009-01-01

    Prior to the workshop two CSNI/WGHOF surveys were distributed. One survey was directed at regulatory bodies and the other was directed at plant licensees. The surveys were: 1 - Regulatory Expectations of Licensees' Arrangements to Ensure Suitable Organisational Structure, Resources and Competencies to Manage Safety (sent to WGHOF regulatory members). The survey requested that the respondents provide a brief overview of the situation related to plant organisations in their country, their regulatory expectations and their formal requirements. The survey addressed three subjects: the demonstration and documentation of organisational structures, resources and competencies, organisational changes, issues for improvement (for both current and new plants). Responses were received from eleven regulatory bodies. 2 - Approaches to Justify Organisational Suitability (sent to selected licensees). The purpose of the survey to was to gain an understanding of how licensees ensure organisational suitability, resources and competencies. This information was used to assist in the development of the issues and subjects that were addressed at the group discussion sessions. Responses were received from over fifteen licensees from nine countries. The survey requested that the licensees provide information on how they ensure effective organisational structures at their plants. The survey grouped the questions into the following four categories: organisational safety functions, resource and competence, decision-making and communication, good examples and improvement needs. The findings from these surveys were used in conjunction with other factors to identify the key issues for the workshop discussion sessions. The responses from these two surveys are discussed briefly in Sections 4 and 5 of this report. More extensive reviews of the regulatory and licensee responses are provided in Appendix 1

  11. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... facilitate and support articulation between the ECT mid-level worker qualification and the professional B EMC degree. Methods. The researchers used an exploratory, sequential mixed-method design, which is characterised by a qualitative phase of research followed by a quantitative phase. This design is ...

  12. Research

    African Journals Online (AJOL)

    supports medical education and research at institutions in 12 ... (CBE). CapacityPlus, led by IntraHealth International, is the USAID-funded ... acquire public health, clinical, and/or research skills, usually through applied learning in a .... If students were evaluated, indicate the type of student (i.e. medical, dental, nursing, etc.) ...

  13. Research

    African Journals Online (AJOL)

    abp

    2017-01-24

    Jan 24, 2017 ... and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined. Results: The .... Centre for Virus Research (CVR) of the Kenya Medical Research. Institute (KEMRI) ... rotavirus dsRNA was run on 10% polyacrylamide resolving gels using a large format .... What is known about this topic. •. Rotavirus is ...

  14. Rationales for regulatory activity

    Energy Technology Data Exchange (ETDEWEB)

    Perhac, R.M. [Univ. of Tennessee, Knoxville, TN (United States)

    1997-02-01

    The author provides an outline which touches on the types of concerns about risk evaluation which are addressed in the process of establishing regulatory guides. Broadly he says regulatory activity serves three broad constituents: (1) Paternalism (private risk); (2) Promotion of social welfare (public risks); (3) Protection of individual rights (public risks). He then discusses some of the major issues encountered in reaching a decision on what is an acceptable level of risk within each of these areas, and how one establishes such a level.

  15. Blocos solo-cal utilizando resíduo da construção civil Soil-lime bricks using building waste

    Directory of Open Access Journals (Sweden)

    S. M. R. Patricio

    2013-03-01

    Full Text Available Novas técnicas vêm sendo desenvolvidas com o objetivo de incentivar o desenvolvimento sustentável e tentar minimizar a degradação ambiental causada pela extração indiscriminada de recursos naturais além da constante geração de resíduos de construção e demolição. Esta pesquisa objetiva avaliar a utilização de resíduos da construção civil, oriundos de demolição, como agente pozolânico na fabricação de blocos solo-cal. As matérias primas convencionais e alternativas (resíduos foram caracterizados por meio dos seguintes ensaios: massa especifica real, área específica, análise granulométrica por peneiramento e por difração á laser,limites de liquidez e plasticidade, análise química e difração de raios X. Para os ensaios tecnológicos foram confeccionados corpos de prova solo-cal no traço 1:10 em peso, com substituição da cal por resíduos nas seguintes proporções: 0, 10, 20, 25, 30, 40, 50 e 75%. Os corpos de prova foram curados por períodos de 28, 60 e 90 dias, em câmara úmida com 100% de umidade relativa, em seguida determinada sua resistência à compressão simples e absorção de água. Com os melhores resultados de resistência a compressão simples, foram moldados blocos solo-cal e solo-cal-resíduo. Os resultados obtidos com os blocos solo-cal incorporados com resíduo evidenciaram valores dentro das especificações das normas da ABNT, apontando que existe viabilidade técnica no aproveitamento de resíduos de demolição para uso na fabricação de blocos solo-cal sem função estrutural.New techniques have been developed with the aim of encouraging sustainable development and try to minimize the environmental degradation caused by indiscriminate extraction of natural resources and the constant generation of building waste. This research aims to evaluate the use building waste, as pozzolanic agent in the soil-lime bricks manufacture. Raw materials conventional and alternatives (waste were

  16. Research

    African Journals Online (AJOL)

    abp

    2017-10-25

    Oct 25, 2017 ... stigma and superstition are known to lead to frequent presentation .... The limited documented research on challenges to help-seeking behaviour for cancer ..... to touch your breast [16] that breast self-examination may cause.

  17. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-10-02

    Oct 2, 2015 ... thought to prevent infection, but recent research has proven otherwise. In addition ... One patient had ophthalmalgia and was exposed to. Kaiy for one year and ... migraine, ear infections, tuberculosis, bone fractures, epilepsy,.

  18. Research

    African Journals Online (AJOL)

    abp

    2016-07-12

    Jul 12, 2016 ... multiple risk factors provides support for multiple-behavior interventions as ... consumption) with smoking therefore needs further research. As such this study .... restaurants, in bars, and on a statewide basis. They preferred to.

  19. Research

    African Journals Online (AJOL)

    The mini-clinical-evaluation exercise (mini-CEX) is a way of assessing the clinical ... Ethical approval for this study was obtained from the Medical Health. Research ..... mini-CEX assessment and feedback session, the greater the likelihood of.

  20. Research

    African Journals Online (AJOL)

    abp

    2016-04-14

    Apr 14, 2016 ... Qualitative data, content analysis approach was used. Results: Overall 422 .... Study design: A mixed method cross-sectional design using both quantitative and qualitative research methods as described by. Hanson et al [33] ...

  1. Research

    International Nuclear Information System (INIS)

    1999-01-01

    Subjects covered in this section are: (1) PCAST panel promotes energy research cooperation; (2) Letter issued by ANS urges funding balance in FFTF restart consideration and (3) FESAC panel releases report on priorities and balance

  2. Research

    African Journals Online (AJOL)

    Research. December 2017, Vol. 9, No. 4 AJHPE 171. During curriculum development, teachers ... Ideally, examiners need an educational method to determine ..... A major focus of this study was addressing the human resource gap when.

  3. Developing regulatory approaches

    International Nuclear Information System (INIS)

    Axelsson, Lars

    2012-01-01

    Lars Axelsson presented SSM progress on oversight of LMfS/SC since the Chester 1 Workshop in 2007. Current SSM approaches for safety culture oversight include targeted safety management and safety culture inspections, compliance inspections which cover aspects of safety management/safety culture and multi-disciplinary team inspections. Examples of themes for targeted inspections include management of ambiguous operational situations or other weak signals, understanding of and attitudes to Human Performance tools, the Safety Department's role and authority and Leadership for safety. All regulatory activities provide inputs for the SSM yearly safety evaluation of each licensee. A form has been developed to capture safety culture observations from inspections and other interactions with licensees. Analysis will be performed to identify patterns and provide information to support planning of specific Safety Culture activities. Training has been developed for regulatory staff to enhance the quality of regulatory interventions on safety culture. This includes a half-day seminar to provide an overview of safety culture, and a workshop which provides more in-depth discussion on cultural issues and how to capture those during regulatory activities. Future plans include guidance for inspectors, and informal seminars on safety culture with licensees

  4. NRC Regulatory Agenda

    International Nuclear Information System (INIS)

    1992-07-01

    This document compilation of all rules on which the NRC has recently completed action, or has proposed action, or is considering action, and all petitions for rule making which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  5. NRC regulatory agenda

    International Nuclear Information System (INIS)

    1993-02-01

    This document is a compilation of all rules on which the NRC has recently completed action, or has proposed action, or is considered action, and all petitions for rulemaking which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  6. NRC Regulatory Agenda

    International Nuclear Information System (INIS)

    1989-07-01

    This document is a compilation of all rules on which the NRC has proposed or is considering action and all petitions for rulemaking which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  7. NRC regulatory agenda

    International Nuclear Information System (INIS)

    1992-11-01

    This document provides a compilation of all rules on which the NRC has recently completed action, or has proposed action, or is considering action, and all petitions for rulemaking which have been received by the Commission and are pending disposition by the Commission. The Regulatory Agenda is updated and issued each quarter

  8. Comments on regulatory reform

    International Nuclear Information System (INIS)

    Hendrie, J.M.

    1982-01-01

    Nuclear regulatory reform is divided into two parts. The first part contains all those matters for which new legislation is required. The second part concerns all those matters that are within the power of the Commission under existing statutes. Recommendations are presented

  9. Comments on regulatory reform

    Energy Technology Data Exchange (ETDEWEB)

    Hendrie, J.M.

    1982-01-01

    Nuclear regulatory reform is divided into two parts. The first part contains all those matters for which new legislation is required. The second part concerns all those matters that are within the power of the Commission under existing statutes. Recommendations are presented.

  10. 3 CFR - Regulatory Review

    Science.gov (United States)

    2010-01-01

    ... as a means of promoting regulatory goals. The fundamental principles and structures governing... review. In this time of fundamental transformation, that process—and the principles governing regulation... the Office of Management and Budget (OMB) has reviewed Federal regulations. The purposes of such...

  11. Code of Conduct on the Safety of Research Reactors

    International Nuclear Information System (INIS)

    2006-09-01

    with the advice of an expert Working Group. The revised draft was again circulated to all Member States for comment, along with the report of the Chairman of the expert Working Group. In March 2004, a final draft of the Code was submitted to the Board of Governors for adoption. When the Board of Governors adopted the Code of Conduct, it requested the Director General to circulate the approved Code of Conduct to all Member States and relevant international organizations and transmit it to the General Conference with a recommendation that the Conference endorse it and call for its wide application. In resolution GC(48)/RES/10.A.8, the 2004 General Conference welcomed the adoption of the Code by the Board, and endorsed the guidance for the safe operation of research reactors set out in the Code. It also encouraged Member States to apply the guidance in the Code to the management of research reactors. Finally, it requested the Secretariat to continue to assist Member States in the implementation of the Code and associated safety guidance within available resources. While the Code of Conduct on the Safety of Research Reactors is non-binding, it should serve as guidance on the development and harmonization of laws, regulations and policies on the safety of research reactors. It provides ''best practice'' guidance to the State, the regulatory body and the operating organization for management of research reactor safety. In accordance with resolution GC(48)/RES/10, Member States are encouraged to use this Code of Conduct as the basis upon which to regulate and conduct research reactor activities.

  12. Gerenciamento de resíduos odontológicos no serviço público

    Directory of Open Access Journals (Sweden)

    Lídia Regina da Costa Hidalgo

    Full Text Available OBJETIVO: Verificar o processo de gerenciamento dos resíduos odontológicos do serviço público de saúde em 11 municípios brasileiros. MATERIAL E MÉTODO: Uma única pesquisadora realizou as visitas e as observações foram anotadas em um roteiro previamente elaborado e testado. RESULTADO: Foram visitadas 50 unidades de saúde, sendo que nenhuma apresentou cópia do plano de gerenciamento de resíduos. Do total de estabelecimentos, 62% realizavam a correta segregação dos resíduos no momento da sua geração. A presença de recipientes adequados a cada tipo de resíduo gerado no consultório odontológico foi observada em 74% dos estabelecimentos e, destes, 94% apresentavam capacidade adequada ao tipo de resíduo gerado. A identificação do tipo de resíduo nas embalagens plásticas bem como anotações identificando o estabelecimento gerador dos resíduos foram encontradas em 8% e 6%, respectivamente. Somente 21% dos estabelecimentos apresentavam locais apropriados, de acordo com as normas vigentes, para o armazenamento dos resíduos até que fosse feita a coleta externa. CONCLUSÃO: Constatou-se na presente pesquisa que a rotina adotada pela rede pública de saúde bucal, no que tange ao gerenciamento de resíduos de saúde, apresentou falhas.

  13. US Nuclear Regulatory Commission 1983 annual report

    International Nuclear Information System (INIS)

    1984-01-01

    The thirteen chapters of this annual report are titled: 1983 highlights/1984 planning; reactor regulation; cleanup at TMI-2; operational experience; nuclear materials; safeguards; waste management; inspection, enforcement and emergency preparedness; cooperation with the states; international programs; nuclear regulatory research; proceedings and litigation; and management and communication

  14. Pre-commercial procurement : regulatory effectiveness?

    NARCIS (Netherlands)

    Apostol, Anca Ramona

    2014-01-01

    Is public procurement of research and development (‘R&D’) services the key to European Union (‘EU’)’s sustainable welfare? Is it being regulated in accordance with economic prescripts for effectiveness? Is the regulatory and policy setting clear and comprehensive in order to stimulate a widespread

  15. US Nuclear Regulatory Commission annual report, 1985. Volume 2

    International Nuclear Information System (INIS)

    1986-01-01

    The decisions and actions of the Nuclear Regulatory Commission (NRC) during fiscal year 1985 are reported. Areas covered include reactor regulation, cleanup at Three Mile Island, analysis and evaluation of operational experience, nuclear materials, waste management, safeguards, inspection, enforcement, quality assurance, emergency preparedness, and nuclear regulatory research. Also, cooperation with the states, international programs, proceedings and litigation, and management are discussed

  16. 76 FR 28102 - Notice of Issuance of Regulatory Guide

    Science.gov (United States)

    2011-05-13

    ... Analysis, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555... qualitative, traditional or probabilistic), data, and criteria for considering risk are appropriate for making... 10 CFR part 52, ``Licenses, Certifications, and Approvals for Nuclear Power Plants.'' Other types of...

  17. The future has come: the 100% RES driven power system is reality

    International Nuclear Information System (INIS)

    Orths, Antje; Borre Eriksen, Peter

    2016-01-01

    The Danish political energy and climate targets fixed in the RES (Renewable Energy Sources) directive require Denmark to reach a 30 % RES share of its total energy consumption in 2020. Besides, Danish national targets aim at wind power production to correspond to 50 % of domestic gross electricity consumption (status in 2015: 42 %). For 2050, the political target is to be free of fossil fuels in the whole energy sector - i.e. including transportation. The major part of variable RES in Denmark is wind energy, the remaining power consumption mainly based on biomass, gas and coal fired central power stations and local CHP plants. Some key figures: at the end of 2015, 5,076 MW wind power capacity and 783 MW of solar power capacity were installed in Denmark, with Danish peak load at ∼6.400 MW and the total electricity consumption at 33.6 TWh. Wind power is split into 3,805 MW onshore and 1.272 MW offshore installations. In 2015, wind power produced 14.1 TWh electricity (9.3 TWh onshore, 4.8 TWh offshore), which made a ∼42 % share of the Danish electricity consumption, while solar power produced 0.6 TWh. The high RES level is already today challenging the system e.g. concerning the need for flexibility on the one hand, or by pushing power plants delivering important system services out of the market on the other hand. To fulfill the political ambitions, new arrangements concerning the technical and market design incentivizing flexibility or ancillary services, such as frequency control and voltage control, are needed and currently under development. This article gives examples and illustrates the urgency by showing a real dispatch in a windy week. (authors)

  18. Les Dynamiques Transfrontalières En Afrique De L'ouest

    International Development Research Centre (IDRC) Digital Library (Canada)

    Si l'approche « classique » de l'intégration régionale, qui a jusqu'à ... mettre en exergue une réalité territoriale matérialisée par l'existence d'une frontière ...... La demande alimentaire des métropoles côtières stimule ainsi la production des ...

  19. Resíduos de aves e suínos: Potencialidades

    Directory of Open Access Journals (Sweden)

    Tiago Luan Hachmann

    2014-05-01

    Full Text Available O crescimento intenso da população mundial aumenta a demanda por alimentos. As carnes de frango e de suíno são as fontes mais exploradas de proteína na alimentação humana. Porém, com os métodos intensivos de produção, esses sistemas tem gerado insatisfação quanto ao aspecto ambiental e tem sido questionados quanto à sua sustentabilidade. A disposição inadequada dos resíduos gerados nos criatórios de suínos e aves afeta diretamente a qualidade do meio ambiente e a saúde pública. Assim deve-se buscar alternativas para minimizar os impactos causados ao meio, melhorando o aproveitamento e destinação desses resíduos. A aplicação desses resíduos nas áreas de produção agrícola é favorável à, tendo em vista que são uma fonte de nutrientes de grande demanda pelas culturas. Além disso é uma forma sustentável para destinação dos resíduos, já que promove seu reaproveitamento de forma a não poluir o ambiente e com alto retorno econômico. Dessa forma é possível aliar preservação ambiental com progresso econômico, promovendo uma produção sustentável.

  20. Bajenu Gox : une approche communautaire pour la santé des mères ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    initiative de Bajenu Gox à l'amélioration de la santé des mères et des enfants dans tout le Sénégal. L'ancien président Abdoulye Wade a fondé ce programme communautaire destiné aux travailleurs de la santé en vue de donner à des femmes ...