WorldWideScience

Sample records for regulation contract management

  1. 76 FR 14543 - Federal Acquisition Regulation; Proper Use and Management of Cost-Reimbursement Contracts

    Science.gov (United States)

    2011-03-16

    ..., Sequence 1] RIN 9000-AL78 Federal Acquisition Regulation; Proper Use and Management of Cost-Reimbursement... other than firm-fixed-price contracts (e.g., cost-reimbursement, time-and-material, and labor-hour...-reimbursement contracts and identifies the following three areas that the Defense Acquisition Regulation Council...

  2. 77 FR 12925 - Federal Acquisition Regulation; Proper Use and Management of Cost-Reimbursement Contracts

    Science.gov (United States)

    2012-03-02

    ...-Reimbursement Contracts AGENCIES: Department of Defense (DoD), General Services Administration (GSA), and... addresses the use and management of cost- reimbursement contracts. DATES: Effective Date: April 2, 2012 FOR...-reimbursement contracts in the following three areas: 1. Circumstances when cost-reimbursement contracts are...

  3. A Story of Three Bank-Regulatory Legal Systems: Contract, Financial Management Regulation and Fiduciary Law

    Directory of Open Access Journals (Sweden)

    Tamar Frankel

    2016-08-01

    Full Text Available How should banks be regulated to avoid their failure? Banks must control the risks they take with depositors' money. If depositors lose their trust in their banks, and demand their money, the banks will fail. This article describes three legal bank regulatory systems: Contract with depositors (U.S.; a mix of contract and trust law, but going towards trust (Japan and a full trust-fiduciary law regulating banks (Israel. The article concludes that bank regulation, which limits the banks' risks and conflicts of interest, helps create trustworthy banks that serve their country best.

  4. Options analysis of managed care contracting and regulation: theory and evidence.

    Science.gov (United States)

    McLean, R A; Magiera, F T

    2000-08-01

    Managed care contracts can be represented as bundles of options. In particular, the managed care provider is short a call option. To hedge the risk involved in such contracts, managed care contractors can construct several types of virtual put options, among them the ownership of facilities. Agency theory and options theory suggest that for-profit managed care plans, in the presence of debt, will engage in less hedging activity than will other managed care plans. Here, the authors test that hypothesis, using data for Florida HMOs in 1995, and they reject the null hypothesis. That managed care organizations act as if they are short a call option raises interesting regulatory issues, including the possibility of using a hedge-based regulatory scheme in place of a net-worth-based scheme.

  5. Contract management survey 2002.

    Science.gov (United States)

    Hoppszallern, Suzanna

    2002-10-01

    Spending on clinical contracts continues to outpace spending on business services, but may be leveling off. The 12th annual Contract Management Survey shows that the performance of clinical vendors is now comparable to business service vendors in meeting savings targets. Both business and clinical vendors are receiving higher marks from hospital leaders, but execs quickly respond to low marks by bringing the service back in-house of changing vendors. This report examines trends in outsourcing, satisfaction levels, the decision-making process, contract features and performance, and spending.

  6. PROCUREMENT AND CONTRACT MANAGEMENT

    CERN Multimedia

    Training & Development Group; Linda Orr-Easo; Tel. 72460; Nathalie Dumeaux; Tel. 78144

    2001-01-01

    We are pleased to announce the launch of a new training on: Procurement and Contract Management (This seminar will be run by CERN experts in French or in English) Level 1 The aim is to raise awareness of the key issues involved. Date : 8 June 2001 This level is open to everyone. Participants should register via our Web page as soon as possible. Level 2 To develop the skills needed to effectively manage contracts, from the Technical, Commercial and Legal aspects. Dates : Three days, Autumn 2001 This Level is open to those who are/will be more directly responsible for procurement and contract management. Participants should have followed Level 1. For a description of the seminar, please consult:   Level 1: http://training.web.cern.ch/Training/MANCO/P9798/9-cm_e.htm Level 2: http://training.web.cern.ch/Training/MANCO/P9798/9-cm2_e.htm

  7. 48 CFR 2452.242-71 - Contract management system.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract management system... 2452.242-71 Contract management system. As prescribed in 2442.1107, insert the following clause: Contract Management System (FEB 2006) (a) The contractor shall use contract management baseline planning...

  8. Contract & agency labour: beyond self-regulation?

    OpenAIRE

    Cotton, Elizabeth

    2010-01-01

    A paper about the regulation of contract labour. Academic and legal aspects as well as case studies of global union federation work to organise and regulate contract labour in Thailand, Pakistan, Colombia, South Korea and at international level.

  9. 6th Workshop on waste management contracts

    International Nuclear Information System (INIS)

    2000-01-01

    The workshop was intended for participants from industry and the service sector and municipalities responsible in particular for the legal aspects involved in the waste management business, namely for concluding the contracts with customers and contractors and for contract management in compliance with the laws and regulations of Germany and the European Union, including the relevant pollution control and monitoring obligations. Participants of the workshop received in-depth information and guidance through discussion of contracts and document types of relevance in this context. (orig./CB) [de

  10. 2001 contract management survey.

    Science.gov (United States)

    2001-10-01

    For the second year running, hospitals are spending more on clinical outsourcing than on business services. The Eleventh Annual Contract Services Survey shows that, in clinical areas, executives use outsourcing to acquire specialized expertise with cost savings secondary. Reducing costs and FTEs are the primary reasons for outsourcing business operations. Business service contracts are more likely to meet expectations for cost savings. Overall, satisfaction levels are up, but in some areas there's still a lot of room for improvement. This report examines current trends in outsourcing, strategies for the future, satisfaction levels, the decisionmaking process, contract features, and costs.

  11. Construction contracts law and management

    CERN Document Server

    Hughes, Will; Murdoch, John

    2015-01-01

    The fifth edition of this bestselling textbook has been thoroughly revised to provide the most up-to-date and comprehensive coverage of the legislation, administration and management of construction contracts. It now includes comparisons of working with JCT, NEC3, and FIDIC contracts throughout. Introducing this topic at the core of construction law and management, this book provides students with a one-stop reference on construction contracts. Significant new material covers: procurement tendering developments in dispute settlement commentary on all key legislation, case law and contract amendments In line with new thinking in construction management research, this authoritative guide is essential reading for every construction undergraduate and an extremely useful source of reference for practitioners.

  12. Dynamics of risk management in the regulated contracting environment of the Brazilian electrical sector; Dinamica da gestao de riscos no ambiente de contratacao regulada do setor eletrico brasileiro

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Fabio Cavaliere de

    2008-11-15

    This thesis analyses the dynamics of risk management in the regulated contracting environment of the Brazilian electrical sector. As in the new model the distribution utilities are obliged to ensure energy contracting to supply their whole markets, these companies became exposed to volume risks related to the demand uncertainties. So the new model following similar directives from the first phase developed management tools to mitigate the new risks mentioned above. As in a well structured market it is expected that the risks should be evenly shared or that risk management tools should be provided for all, this work intended to analyze the dynamics of the designed mechanisms and their impacts over the regulated market. In this work the risks of the electricity markets are studied and the management tools devised for the Brazilian market are identified. Finally for understanding the dynamics a thorough analysis of the auctions, of the mechanism for compensation of surplus and deficits and tariffs are carried on. The results show that the management tools were regularly employed by distribution companies, but the risks were merely transferred to the captive customers leading to distortions and asymmetries that conflict with the basis that guided the second phase of the reform. The work proposes remedial actions to mitigate the observed impacts and to provide risk management tools to the captive customer. (author)

  13. Invalidity of contract: legislative regulation and types

    Directory of Open Access Journals (Sweden)

    Василь Іванович Крат

    2017-09-01

    Full Text Available Invalidity contracts always attracted attention researchers. Without regard to it, in modern conditions there is an enormous layer of the problems related to invalidity contract, that to require a doctrine and utilitarian comprehension. The article is sanctified to research invalidity contract. In the article analyses problems of the legislative regulation and types of invalidity contract through the prism of judicial practice. In the Civil code of Ukraine, a voidable contract sets as a common rule. A voidable of the contract is incarnated in the so-called «virtual» invalidity when only the most typical grounds are enumerated. However, even such approach does not allow to overcome all possible cases that arise up in practice. Such situation touches possibility of voidable contracts concluded with the purpose of to shut out the appeal of claim to the property of the debtor. Therefore it follows to set general rules in relation to voidable contracts of the debtor. A nullity of the contract takes place only in the case when there is the direct pointing of law on the qualification of that or another contract as the nullity. The nullity of contract in the Civil code of Ukraine is constructed by means of «textual» invalidity. There are no single attempts to use the construction of «virtual» invalidity in judicial practice when there is the direct pointing of law on the qualification of that or another contract as the nullity, that is impermissible. Methodologically incorrectly to carry out identifying of invalidity contract and obligation with the aim of providing of application of different after the rich in content filling norms.

  14. Price management mechanisms and the gas contract

    International Nuclear Information System (INIS)

    Dickson, D.J.

    1996-01-01

    Pricing objectives and risk management strategies that can be achieved through the proper use of the standard gas contract, were discussed. Main topics of discussion were: (1) gas sales contract and convertible pricing, (2) gas contract and imbedded hedging, gas contracts and exchange traded instruments, (4) gas contracts fixed for floating swaps, and OTC options and exotics, (5) options and exotic price structures, and (6) advantages and disadvantages of using the gas contract versus the swap agreement

  15. R and D contract management systems in the USA (Attachment); Beikoku ni okeru R and D contract kanri system (tenpu shiryohen)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-01

    Presented herein is the attachment for 'R and D contract management systems in the USA'. The major contents include regulations governing the R and D contracts, procedures for the R and D contracts, financial procedures for the R and D contracts, procedures for the alternative R and D contracts, financial management of the R and D contracts, and activities for the management of the contract processes by electronic systems. (NEDO)

  16. R and D contract management systems in the USA (Attachment); Beikoku ni okeru R and D contract kanri system (tenpu shiryohen)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-01

    Presented herein is the attachment for 'R and D contract management systems in the USA'. The major contents include regulations governing the R and D contracts, procedures for the R and D contracts, financial procedures for the R and D contracts, procedures for the alternative R and D contracts, financial management of the R and D contracts, and activities for the management of the contract processes by electronic systems. (NEDO)

  17. Analysis of the 314th Contracting Squadrons Contract Management Capability Using the Contract Management Maturity Model (CMMM)

    National Research Council Canada - National Science Library

    Jackson, Jr, Carl J

    2007-01-01

    .... The purpose of this research project is to analyze the 314th Contracting Squadron contracting processes and requirement target areas for improvement efforts by the application of the Contract Management Maturity Model (CMMM...

  18. Towards Certified Management of Financial Contracts

    DEFF Research Database (Denmark)

    Bahr, Patrick; Berthold, Jost; Elsman, Martin

    2014-01-01

    . The seminal work by Peyton-Jones and Eber on financial contracts shows how an algebraic approach to contract specification can be used for valuation of contracts (when combined with a model of the underlying observables) and for managing how contracts evolve under so-called fixings and decision......-taking, with the contracts eventually evaporating into the empty contract, for which no party have further obligations. The ideas have emerged into Eber's company LexiFi, which has become a leading software provider for a range of financial institutions, with all contract management operations centralised around a domain......Banks and financial institutions nowadays often use domain-specific languages (DSLs) for describing complex financial contracts, in particular, for specifying how asset transfers for a specific contract depend on underlying observables, such as interest rates, currency rates, and stock prices...

  19. 41 CFR 101-1.102 - Federal Property Management Regulations.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Federal Property Management Regulations. 101-1.102 Section 101-1.102 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation...

  20. 76 FR 7522 - Federal Acquisition Regulation; Enhancing Contract Transparency

    Science.gov (United States)

    2011-02-10

    ... transparency while retaining the protection of information that should be considered in the contracting process... the need for transparency in Government contracting information and believe these recommendations... Regulation; Enhancing Contract Transparency AGENCY: Department of Defense (DoD), General Services...

  1. Management of transport and handling contracts

    CERN Document Server

    Rühl, I

    2004-01-01

    This paper shall outline the content, application and management strategies for the various contracts related to transport and handling activities. In total, the two sections Logistics and Handling Maintenance are in charge of 27 (!) contracts ranging from small supply contracts to big industrial support contracts. The activities as well as the contracts can generally be divided into four main topics "Vehicle Fleet Management"; "Supply, Installation and Commissioning of Lifting and Hoisting Equipment"; "Equipment Maintenance" and "Industrial Support for Transport and Handling". Each activity and contract requires different approaches and permanent adaptation to the often changing CERN's requirements. In particular, the management and the difficulties experienced with the contracts E072 "Maintenance of lifting and hoisting equipment", F420 "Supply of seven overhead traveling cranes for LHC" and S090/S103 "Industrial support for transport and handling" will be explained in detail.

  2. Career Management and the Changing Psychological Contract.

    Science.gov (United States)

    Atkinson, Carol

    2002-01-01

    A 1993 survey in a British bank revealed a lack of strategic approaches to career management and a negative psychological contract. A 2000 follow-up showed that employees viewed the new contract as a regression from a relational to a transactional approach. They had increased responsibility for career development, but management failed to provide…

  3. Assessment of Navy Contract Management Processes

    Science.gov (United States)

    2016-04-30

    capability? • 85% of quality problems are related to processes, while only 15% of problems are controlled by individual workers ( Deming , 1986...eligible participants: 369 • Total surveys completed: 185 • Response rate: 50% CONTRACT MANAGEMENT MATURITY MODEL© MATURITY LEVEL 5...Measurement – Organizations systematically use performance metrics to measure the quality and evaluate the effectiveness of the contract management

  4. Quality management and quality assurance contracts

    International Nuclear Information System (INIS)

    Teichler, M.

    1991-01-01

    Quality assurance contracts belong to the most important instruments of quality management systems. As a result of such contracts, quality control is to be done not only by the buyer, but is made a task to be fulfilled by the manufacturer. The author of the article shows that quality assurance contracts do change the contractual relationship between supplier and buyer, but have no effect on economic and practical conditions. This is so because quality assurance contracts apply only to warranty claims, which play a subordinate role in the legal relationship between producer and buyer, or producer and consumer, as compared to the claims for damages arising out of the contracts. (orig.) [de

  5. 41 CFR 128-1.101 - Justice Property Management Regulations.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Justice Property Management Regulations. 128-1.101 Section 128-1.101 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF JUSTICE 1-INTRODUCTION 1.1-Regulation System § 128-1...

  6. Defense Contract Management Command Support to System Acquisition Program Managers

    National Research Council Canada - National Science Library

    1999-01-01

    .... This report discusses the planning of contract administration office support to system acquisition program managers through the program integration process and the customer support outreach program...

  7. Contract Design: Risk Management and Evaluation.

    Science.gov (United States)

    Mühlbacher, Axel C; Amelung, Volker E; Juhnke, Christin

    2018-01-12

    accuracy. For this reason, it is necessary to clearly regulate the method of risk adjustment in the integrated care contract. The series of three articles on contract design has shown that coordination and motivation problems in designing healthcare contracts cannot be solved at no-costs. Moreover, it became clear, that complete contracts in healthcare are unrealistic and that contracts do always include certain uncertainties. These are based on the risk of random, and no contracting party can control these risks completely. It is also not possible to fully integrate these risks in the contract or to eliminate these risks by the parties.

  8. Contract Design: Risk Management and Evaluation

    Directory of Open Access Journals (Sweden)

    Axel C. Mühlbacher

    2018-01-01

    of risk adjustment have widely differing model and forecast accuracy. For this reason, it is necessary to clearly regulate the method of risk adjustment in the integrated care contract.  Conclusions and discussion: The series of three articles on contract design has shown that coordination and motivation problems in designing healthcare contracts cannot be solved at no-costs. Moreover, it became clear, that complete contracts in healthcare are unrealistic and that contracts do always include certain uncertainties. These are based on the risk of random, and no contracting party can control these risks completely. It is also not possible to fully integrate these risks in the contract or to eliminate these risks by the parties.

  9. Financial Management: Reopening of Contracts in the Mechanization of Contract Administration Services System

    National Research Council Canada - National Science Library

    Granetto, Paul

    2003-01-01

    .... In anticipation of transitioning to the new contract payment system, the Defense Finance and Accounting Service and the Defense Contract Management Agency were attempting to close out as many contracts as possible...

  10. 78 FR 41331 - Federal Acquisition Regulation; Publicizing Contract Actions; Contracting by Negotiation

    Science.gov (United States)

    2013-07-10

    ... DEPARTMENT OF DEFENSE GENERAL SERVICES ADMINISTRATION NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 48 CFR Parts 5 and 15 Federal Acquisition Regulation; Publicizing Contract Actions; Contracting by Negotiation CFR Correction In Title 48 of the Code of Federal Regulations, Chapter 1 (Parts 1 to 51), revised as of October 1, 2012, on page 115, in...

  11. Integrated project management type contracts

    International Nuclear Information System (INIS)

    Heisler, S.I.

    1975-01-01

    The concept of integrated project management represents a single source to which the owner can turn for all project management functions excepting for those relating to outside parties such as site purchase, personnel selection etc. Other functions such as design, procurement, construction management, schedule and cost control, quality assurance/quality control are usually handled by the integrated project manager as the agent of the owner. The arrangement is flexible and the responsibilities can be varied to suit the size and experience of the owner. Past experience in the United States indicates an increase in the trend toward IPM work and it appears that overseas this trend is developing also. (orig./RW) [de

  12. Information technology: management issues in outsource contracts.

    OpenAIRE

    2008-01-01

    This study concerns the investigation of management issues within information technology outsourcing contracts. The information technology outsourcing life cycle is used as the flow structure for the investigation. The associated user expectations that occur in each of the phases of the information technology outsourcing life cycle are identified. Following the identification of the management and user expectation issues in each phase of the outsource life cycle, the “Coetzee solution framewo...

  13. The regulation of peculiarities of electronic contracting: comparative analysis

    Directory of Open Access Journals (Sweden)

    Наталія Юліївна Філатова

    2017-12-01

    Full Text Available Contract formation by electronic means nowadays is a widespread phenomenon. Nevertheless electronic contracting has been thoroughly explored by scholars all over the world and regulated both internationally and domestically, there still remain some issues which need to be carefully analyzed. In our view, the most essential question raised by electronic contracting is whether there is a need to amend substantial contract law provisions with regard to peculiarities of contracts concluded by electronic means. Seeking the answer to this question several approaches have been formulated, but none of them seems to be completely appropriate. In this paper the answer is also attempted to be found. For this purpose a comparative analysis of doctrine, legislation and judicial practice of certain states is performed. Particularly, offer, acceptance and moment of electronic contract formation are explored. On the basis of this research the following conclusion is done: amendments to substantial contract law provisions are not always necessary to improve the regulation of electronic contracting. Nevertheless the provisions of law should be applied correctly to the disputes arising from electronic contract formation taking into account the peculiarities of such contracts.

  14. 41 CFR 102-2.5 - What is the Federal Management Regulation (FMR)?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is the Federal Management Regulation (FMR)? 102-2.5 Section 102-2.5 Public Contracts and Property Management Federal... MANAGEMENT REGULATION SYSTEM Regulation System General § 102-2.5 What is the Federal Management Regulation...

  15. AGENCY CONTRACTS – EXISTING REGULATIONS IN ROMANIAN LAWS

    Directory of Open Access Journals (Sweden)

    Cristina Cojocaru

    2012-11-01

    Full Text Available Agency contracts are created as legal instruments with a highly important role for the business activity, given that they are the basis for professional intermediation. Regulations have changed in time, in an attempt to offer a better apprehension of the notion and applicability of this type of contract through the legislative framework. In Romanian law, this type of contract was regulated for the first time by Law no. 509 in 2002 on permanent commercial agents, law that was repealed when the new Civil Code came into force on October 1, 2011.

  16. The missing link between maintenance contracts and flexible asset management

    OpenAIRE

    Marttonen-Arola, Salla; Viskari, Sari; Kärri, Timo

    2013-01-01

    The paper shows how additional value can be created in maintenance collaboration through integrating the features of flexible asset management into maintenance contracts. We expand the traditional typology of maintenance contracts and introduce a new contract type, flexible asset management contracts. Also value sharing in the new contract type is discussed. Our logic for sharing the value is based on reaching for win-win situations in industrial maintenance collaboration. Finally, we present...

  17. 48 CFR 915.404-4-71 - Profit and fee-system for construction and construction management contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Profit and fee-system for construction and construction management contracts. 915.404-4-71 Section 915.404-4-71 Federal Acquisition... Contract Pricing 915.404-4-71 Profit and fee-system for construction and construction management contracts. ...

  18. Self-regulation in dentistry and the social contract.

    Science.gov (United States)

    Holden, A C L

    2016-10-21

    This article looks at the General Dental Council (GDC) and dental regulation from the perspective of social contract theory. Self-regulation is a requirement for the dental profession to exist within such a contract with society and this article seeks to examine the effects of the GDC upon the social contract. The GDC maintains that it is independent of the dental profession and while this may be true when discussing impartiality, the existence and purpose of the GDC is intrinsically intertwined with the dental profession. This article will show that the GDC has acted in a manner that has a negative impact upon the social contract between the dental profession and society and that for the dental profession to maintain its status and ability to place patients first, the GDC needs to re-evaluate its role and attitudes.

  19. Multiple Challenges of Flexible Workforce Management: the contract managers experience

    Directory of Open Access Journals (Sweden)

    Yana Torres de Magalhães

    2010-07-01

    Full Text Available This article presents the results of a survey that had the purpose to evaluate the human resources (HR practices adopted by a Brazilian industrial corporation from the viewpoint of contracting out managers to deal with four flexible workforce management challenges: qualification; quality; commitment; standardization of outsourcing services. These HR practices are still little discussed by scholars. So, this is the main contribution of this article. It is also virtually nonexistent in the literature studies that encompass analysis about HR practices to deal with major challenges of outsourcing throughout the viewpoint of contracting out managers. We performed 15 semi-structured interviews with contracting out managers. It was also performed a documental analysis about the rules of outsourcing practices of the corporation. We found management practices to deal with each of the four challenges presented. The management of contracts and the provision of training programs were the most prominent of the related practices. The results show that Brazillian labor laws contribute to the segregation of temporary workers, because the companies avoid a more direct relationship fearing legal constraints. Although several efforts were put to improve the work conditions of the flexible workforce, these workers are still stigmatized, seen and treated as less important than direct employers; this causes negative impacts on commitment. The decision to use flexible workforce by companies is still mainly due to cost savings. Therefore, there is still a long way to improve HR practices related to temporary workers in order to avoid losses for all the social actors envolved.

  20. LEGAL REGULATION OF ADMINISTRATIVE CONTRACTS IN BOSNIA AND HERZEGOVINA

    Directory of Open Access Journals (Sweden)

    Edina Šehrić

    2016-09-01

    Full Text Available The institute of administrative contract was mentioned for the first time in the legislation of our country in the Preliminary Draft to the Law on Amandments of the Law on Administrative Procedure of Bosnia and Herzegovina from 2012. Although insufficiently, the first step is made towards fullfillment of the reform requirements in the area of admisitrative procedure on the way to the European integration and in accordance with the changed role of administration and the need for improvement of cooperation between the administration and citizens, or legal entities. In Bosnia and Herzegovina there is still no general legal regulation of administrative contracts, but administrative contracts are subjects to specific laws and as such already exist in the legal system. After some introductory remarks, the paper deals with the concept and characteristics of administrative contracts, and also presents legal regulation of administrative contracts highlighting their specificities and differences in relation to private law contracts. The importance of general legal norm governing administrative contracts is especially emphasized, as well as their importance for reform processes in our country. Accordingly, the importance of introducing a complaint as a legal remedy that a client can use if the public authority fails to meet contractual obligations is pointed out, but also the possibility of judicial protection in case of legal dispute.

  1. Risk management and oil trading contracts

    International Nuclear Information System (INIS)

    Sas, B.

    1992-01-01

    The oil market provides an excellent case study for an analysis of the commodity trading risks and the development of contractual instruments and market structures to meet these risks. The paper identifies the main risks, namely performance, credit/payment, price, regulatory, fiscal, and ''trading'' risk. A conceptual framework provides the basis to trace the evolution of the risk management instruments from relational (e.g. long-term), through ''transactional'' (e.g. spot and forwards) to ''institutional'' (e.g. futures and options) and finally ''pricing'' (e.g. swaps and trigger pricing) contracts. (author)

  2. 78 FR 68829 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Contract...

    Science.gov (United States)

    2013-11-15

    ... DFARS 252.232-7007, Limitation of Government's Obligation. DFARS subpart 232.7, Contract [[Page 68830...; Defense Federal Acquisition Regulation Supplement; Contract Financing AGENCY: Defense Acquisition... and OMB Number: Defense Federal Acquisition Regulation Supplement (DFARS) Part 232, Contract Financing...

  3. 41 CFR 101-1.101 - Federal Property Management Regulations System.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Federal Property Management Regulations System. 101-1.101 Section 101-1.101 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1...

  4. Why Training for Service Contract Management is Mission Essential

    National Research Council Canada - National Science Library

    Friar, Allen

    2005-01-01

    ... Programs provide vital services and act as force multipliers for forward deployment units. Consequently, a transformation in contracting and acquisition leadership along with proper planning is necessary to manage contracts...

  5. The Contract Management Body of Knowledge: A Comparison of Contracting Competencies

    Science.gov (United States)

    2013-12-01

    and supply chain management policies in an effort to deliver higher returns for their companies ( KPMG , 2012). As purchasing becomes increasingly more...conservation, hazardous materials , and ozone-depleting substances (NCMA, 2011). Contract Structures (1.5) has to do with identifying specific contract types...discusses time and material contracts as well as cost, performance, and delivery incentives. Incentive and award-fee contracts pertaining to fixed-price

  6. Outsourcing Contract Success: A Quality Management Perspective

    OpenAIRE

    Vanita Yadav; B.A. Metri

    2010-01-01

    Despite the phenomenal growth in outsourcing of various business functions like Enterprise Systems outsourcing, IT outsourcing, and Business Process outsourcing, there has been relatively less attention given to the high-risk area of outsourcing contracts. In this regard, contract has been the conventional medium for governing outsourcing relationships. This study aims to bring forward the importance of quality in the entire contracting process, involving contract planning, pre-contract negot...

  7. Measuring Satisfaction in the Program Manager, Procuring Contracting Officer Relationship

    Science.gov (United States)

    1997-12-01

    Contracting Officer) and one of her customers (a U. S. Navy Program Manager ). From an examination of this relationship , the most appropriate criteria... Customer Satisfaction, Performance Measurement, Metrics, Contracting, Program Management 17. SECURITY CLASSIFICATION OF REPORT Unclassified...methodology for developing an instrument to measure the satisfaction of their customers , Navy Program Managers . The purpose of this thesis was to develop

  8. Dynamic contracting mechanism for pavement maintenance management

    NARCIS (Netherlands)

    Demirel, H.C.; De Ridder, H.A.J.

    2013-01-01

    Technological advances, financial possibilities and changes of demands have increasingly affected the pavement maintenance environment for outsourcing in recent years. This induces complexity in the contracting methods of pavement maintenance activities. Despite the fact that current contracting

  9. Measuring Satisfaction in the Program Manager, Procuring Contracting Officer Relationship

    National Research Council Canada - National Science Library

    Gray, John

    1997-01-01

    .... To comply with this Executive Order, Navy contracting offices require an effective methodology for developing an instrument to measure the satisfaction of their customers, Navy Program Managers...

  10. Certified symbolic management of financial multi-party contracts

    DEFF Research Database (Denmark)

    Bahr, Patrick; Berthold, Jost; Elsman, Martin

    2015-01-01

    Domain-specific languages (DSLs) for complex financial contracts are in practical use in many banks and financial institutions today. Given the level of automation and pervasiveness of software in the sector, the financial domain is immensely sensitive to software bugs. At the same time...... automatically extract a Haskell implementation of an embedded contract DSL along with the formally verified contract management functionality. This approach opens a road map towards more reliable contract management software, including the possibility of analysing contracts based on symbolic instead of numeric...

  11. Managing the financial cost of exception to contracting standards

    DEFF Research Database (Denmark)

    Henschel, Rene Franz

    2008-01-01

    In managing financial cost of exception to contracting standards, the first step is to put up an intelligent contract standards exception monitoring system The next step is to maintain tailor-made, fair and transparent contracting standards The third step is to eliminate unnecessary information...... and repetitiveness in contracting standards The fourth step is to enable your organization and the customers or suppliers to handle the necessary exceptions themselves Finally you should consider the use of independent contracting standards and elimination of your own standards as a tool in managing the cost...

  12. Trust-based or performance-based management: a study of employment contracting in hospitals.

    Science.gov (United States)

    Pettersen, Inger Johanne

    2011-01-01

    Hospitals are frequently changing managerial practices due to numerous public sector reforms taking place. In general, these reforms include the making and monitoring of contracts that regulate relations between the hospitals and their professional staffs. The aim of this paper is to discuss some main characteristics of the contracts that regulate the perceived relations between physicians as employees and the public hospital as employer. The theoretical framework is based on a contract theory approach. The empirical data is based on survey data from full-time employed physicians in the medical and surgical divisions in one of the largest university hospitals in Norway. This study shows that perceived obligations and psychological contracts indicate high degree of relational contracts between the hospital and the physicians. These socio-cultural elements should be recognized as important mechanisms of coordination and communication when policy makers and hospital managers are designing hospital management control systems. Copyright © 2009 John Wiley & Sons, Ltd.

  13. R and D contract management systems in the USA; Beikoku ni okeru R and D contract kanri system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-01

    Outlined herein are the US Government's R and D contract management, which is considered to have greatly contributed to promotion of innovation in the USA. The procedures for the R and D contracts are managed through the mechanisms of the (government procurement), following the FAR (Federal Acquisition Regulations) that govern the government procurement rules. The procedural flow includes planning, public announcement of inviting the application documents, examination of the applications, negotiations, granting the fund, project management, suspension of the project and completion of the project. The audition sometimes takes several years to complete. The staff managing the individual contract is fairly specialized, and a team consisting of several professionals is responsible for each project. The substantial lifetime training systems the contract officers can receive are established. The alternative contract system encourages the applications from consortiums, and private enterprises frequently tie up with academic organizations to apply for the funds. Granting the funds to consortiums have many advantages, e.g., cost sharing and technological transfer. (NEDO)

  14. Project Hanford management contract quality improvement project management plan; TOPICAL

    International Nuclear Information System (INIS)

    ADAMS, D.E.

    1999-01-01

    On July 13, 1998, the U.S. Department of Energy, Richland Operations Office (DOE-RL) Manager transmitted a letter to Fluor Daniel Hanford, Inc. (FDH) describing several DOE-RL identified failed opportunities for FDH to improve the Quality Assurance (QA) Program and its implementation. In addition, DOE-RL identified specific Quality Program performance deficiencies. FDH was requested to establish a periodic reporting mechanism for the corrective action program. In a July 17, 1998 response to DOE-RL, FDH agreed with the DOE concerns and committed to perform a comprehensive review of the Project Hanford Management Contract (PHMC) QA Program during July and August, 1998. As a result, the Project Hanford Management Contract Quality Improvement Plan (QIP) (FDH-3508) was issued on October 21, 1998. The plan identified corrective actions based upon the results of an in-depth Quality Program Assessment. Immediately following the scheduled October 22, 1998, DOE Office of Enforcement and Investigation (EH-10) Enforcement Conference, FDH initiated efforts to effectively implement the QIP corrective actions. A Quality Improvement Project (QI Project) leadership team was assembled to prepare a Project Management Plan for this project. The management plan was specifically designed to engage a core team and the support of representatives from FDH and the major subcontractors (MSCs) to implement the QIP initiatives; identify, correct, and provide feedback as to the root cause for deficiency; and close out the corrective actions. The QI Project will manage and communicate progress of the process

  15. 41 CFR 105-1.101 - General Services Administration Property Management Regulations.

    Science.gov (United States)

    2010-07-01

    ...-INTRODUCTION 1.1-Regulations System § 105-1.101 General Services Administration Property Management Regulations... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false General Services Administration Property Management Regulations. 105-1.101 Section 105-1.101 Public Contracts and Property...

  16. Post contract / Project management in Nuclear Malaysia

    International Nuclear Information System (INIS)

    Mohd Jamil Hashim

    2010-01-01

    Full-text: Post contract is a period from issuance certificate of practical completion until final statement of account of the project. If this procedure not completed the whole project will at large, create customers un-satisfaction, contractual obligation not complied, record not completed and financial setback. With the usage terms of contract, standard JKR circulars, treasury circulars and JKR quality manual BKJ will produce new Standard operating procedure, SOP with regards to these matters. In doing so it shall increase customer satisfaction and reduce time to finalise project and provide good record system. Keywords: Post contract, certificate of practical completion, final account, customer satisfaction, Standard operating procedure. (author)

  17. Asset Allocation and Optimal Contract for Delegated Portfolio Management

    Science.gov (United States)

    Liu, Jingjun; Liang, Jianfeng

    This article studies the portfolio selection and the contracting problems between an individual investor and a professional portfolio manager in a discrete-time principal-agent framework. Portfolio selection and optimal contracts are obtained in closed form. The optimal contract was composed with the fixed fee, the cost, and the fraction of excess expected return. The optimal portfolio is similar to the classical two-fund separation theorem.

  18. An Analysis of Category Management of Service Contracts

    Science.gov (United States)

    2017-12-01

    comprised of four steps to guide future category management teams in analyzing data and applying Category Management principles through the use of...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT AN ANALYSIS OF CATEGORY MANAGEMENT OF SERVICE CONTRACTS December 2017...Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302, and to the Office of Management and Budget, Paperwork Reduction Project

  19. Managing the relational character of public-private partnership contracts

    Directory of Open Access Journals (Sweden)

    Cvetković Predrag

    2015-01-01

    Full Text Available A public-private partnership contract has the character of a relational contract. Relational contracts are incomplete agreements governing transactions where the contracting parties have mutually agreed that it is impossible or economically inefficient to contractually define ex ante possible difficulties and contingencies in the contract implementation, nor the difficulties and contingencies underlying the ex post control of contract performance by a third entity (court or arbitration. Considering the methodology of managing relational contracts, it is essential that the theory of relational contracts does not advocate for the establishment of relational contracts as a separate category of contracts, with specifically designated contractual instruments. This theory defines the relational contract as a category which legitimizes 'the relational mode' of a particular contract. The methodology of relational contracts is important for contracts on public-private partnership as it ensures that the contractual relationship is aligned with the changes in the immediate environment where the PPP contract operates. The aforementioned alignment has two aspects. The first one is the ex ante aspect of the alignment which is primarily aimed at preventing the detrimental effect of such alignment to the public partner's interests. Therefore, the intent to prevent such an effect shall be taken into account when defining the criteria for the selection of the most favorable private partner and the best offer. At the same time, it is essential to establish verifiable standards for measuring the private partner performance in the phase of contract implementation. For this goal to be achieved, it is crucial to specify the subject matter of the private partner's obligations, to establish the priority rank of PPP project objectives, to elaborate on the specific requirements governing the eligibility of private partners to participate in the bidding process, to specify

  20. Taboos and social contracts: Tools for ecosystem management ...

    African Journals Online (AJOL)

    Traditional taboos and social contracts played an important role in managing the Manambolomaty RAMSAR site. Taboos are defined as a prohibition imposed by social custom as a protective measure' and social contracts are – in conservation sense – a common agreement for achieving conservation, sustainable ...

  1. 48 CFR 301.607-78 - Contracting Officer designation of a Program/Project Manager as the Contracting Officer's...

    Science.gov (United States)

    2010-10-01

    ... designation of a Program/Project Manager as the Contracting Officer's Technical Representative. 301.607-78... Contracting Officer designation of a Program/Project Manager as the Contracting Officer's Technical... acquisition. However, for those individuals serving as a Program or Project Manager under a FAC-P/PM...

  2. Organization and management of the LHC civil-engineering contracts

    CERN Document Server

    Watson, T

    1999-01-01

    Since July 1994, the CERN Civil Engineering group within the ST division has been preparing and engaging contracts related to the Large Hadron Collider (LHC) project. Several of these contracts have values in excess of 10 MCHF and will be executed over a number of years; as such they represent an important part of the infrastructure works required for the LHC. To date, in excess of two hundred and fifty companies have been consulted in relation to these contracts. Contracts or orders have been placed with over thirty companies or joint ventures of companies from nearly all the CERN Member States. This paper aims to show the inter-relationships between these contracts and how the Civil Engineering group is carrying out the management of these important LHC contracts. The organization of the group will be explained along with the roles of individual members within the group.

  3. Management of Contract Waivers and Deviations for Defense Systems

    National Research Council Canada - National Science Library

    1998-01-01

    This report is the fourth and final in a series of reports resulting from our audit of management of contract waivers and deviations for Defense systems and summarizes our overall evaluation. Report...

  4. Privacy Impact Assessment for the Integrated Contracts Management System

    Science.gov (United States)

    The Integrated Contracts Management System collects contact information and other Personally Identifiable Information (PII). Learn how this data will be collected in the system, how it will be used, access to the data, and the purpose of data collection.

  5. 14 CFR 91.1003 - Management contract between owner and program manager.

    Science.gov (United States)

    2010-01-01

    ... program manager. 91.1003 Section 91.1003 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... RULES Fractional Ownership Operations § 91.1003 Management contract between owner and program manager. Each owner must have a contract with the program manager that— (a) Requires the program manager to...

  6. Italy. Electrical contract management in local government

    International Nuclear Information System (INIS)

    Carsana, C.

    1999-01-01

    The technical and economical assessment of electric energy consumption of a public administration body (province) shows remarkable opportunities of reducing energy costs. This calls for a continuous monitoring of the supply contract parameters. It is also discussed the solution concerning the transparency in supplier-customer relationship [it

  7. Contract en conflict : Strategisch Management van Inkooptransacties

    NARCIS (Netherlands)

    Rooks, Gerrit

    2002-01-01

    Dissertation of the University of Utrecht The reality of business relations is opposed to the assumptions commonly held by legal experts on the role of contract law in society, or so Macaulay (see his classic 1963 study) would have us believe. Empirical studies Macaulay conducted in the United

  8. Contract Management: Organisational and Legal Form of Hotel Networks

    OpenAIRE

    Burak Tatyana V.

    2013-01-01

    Hotel business has been the most dynamic and profitable segment of economy, which is characterised with a high degree of internationalisation of capital and international character, during the recent decades. We clearly observe development of national and international hotel networks at this stage. Management contract is one of the methods of development and creation of hotel networks. The article describes theoretical basis of introduction of the contract management into the hotel business, ...

  9. Financial Management: Contracts Classified as Unreconcilable by the Defense Finance and Accounting Service Columbus (Contract DAAA09-81-G-2008-0031)

    National Research Council Canada - National Science Library

    Granetto, Paul J; Kornides, James L; Issel, John K; Knight, Clarence E., III; Frawley, John; Bennett, Karen M

    2005-01-01

    .... Defense Contract Management Agency (DCMA), Pittsburgh, Pennsylvania, personnel stated that the former Defense Contract Administration Services Region Philadelphia initially paid the contract until the payment function was transferred...

  10. Comparative analysis between the manager contract and the administrator contract in the activity of hotel services from Romania

    Directory of Open Access Journals (Sweden)

    Neacșu, A.

    2012-01-01

    Full Text Available In the activity of any hotel company, the manager or the administrator plays an important role; that is why the relationships of the hotel units with managers and administrators must be well defined and assumed by both sides by means of specific contracts. Between the manager contract and the administrator contract there are similarities, but also differences. This paper analyzes the advantages and disadvantages that the two contracts present and also the situations in which they are recommended.

  11. Contract Management Process Maturity: Empirical Analysis of Organizational Assessments

    Science.gov (United States)

    2009-08-27

    with the National Contract Management Association (NCMA), a Certified Purchasing Manager ( CPM ) with the Institute for Supply Management (ISM), and a...include advertising procurement opportunities, conducting industry and pre-proposal conferences, and amending solicitation documents as required. 4...with organizational core processes include advertising procurement opportunities, conducting solicitation and pre-proposal conferences, and amending

  12. Raise the management level of EPC contracting in six aspects

    International Nuclear Information System (INIS)

    Wang Baowei; Feng Shoujia

    2010-01-01

    Nuclear power construction develops rapidly today and EPC contracting for nuclear power projects, as a strategic decision of CNNC, has become a tendency. The target of engineering management can be smoothly realized or achieved by doing a good job in the following six aspects: effective communication between divisions of project department, high-degree consistency of managerial concepts for project management staff, clear objective for different divisions in the project department, presence of rules to be observed in construction management work, avoidance of human-initiated errors in the project, and clear distinction of management control concept. It is hoped that, through exchange and practice, management procedures and consciousness for EPC contracting can be further standardized and thus the level of management for EPC contracting will be raised finally. (authors)

  13. Raise the management level of EPC contracting in six aspects

    International Nuclear Information System (INIS)

    Wang Baowei; Feng Shoujia

    2010-01-01

    Nuclear power construction develops rapidly today and EPC contracting for nuclear power projects, as a strategic decision of CNNC, has become a tendency. The target of engineering management can be smoothly realized or achieved by doing a good job in the following six aspects:effective communication between divisions of project department, high-degree consistency of managerial concepts for project management staff, clear objective for different divisions in the project department, presence of rules to be observed in construction management work, avoidance of human-initiated errors in the project, and clear distinction of management control concept. It is hoped that, through exchange and practice, management procedures and consciousness for EPC contracting can be further standardized and thus the level of management for EPC contracting will be raised finally. (authors)

  14. 75 FR 29547 - Federal Acquisition Regulation; Information Collection; Contract Financing

    Science.gov (United States)

    2010-05-26

    ...; Information Collection; Contract Financing AGENCIES: Department of Defense (DoD), General Services... previously approved information collection requirement concerning contract financing. Public comments are... substantially changed the statutory authorities for Government financing of contracts. Sections 2001(f) and 2051...

  15. 25 CFR 900.216 - What other statutes and regulations apply to contract disputes?

    Science.gov (United States)

    2010-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Post-Award Contract Disputes § 900.216 What other statutes and regulations apply to... 25 Indians 2 2010-04-01 2010-04-01 false What other statutes and regulations apply to contract...

  16. Providing Technical Expertise for Effective Contract Management

    Science.gov (United States)

    2011-04-12

    back to both the finance leg and the contracting leg . In order to avoid a conflict of interest or give the impression of 4 any improprieties...each leg of this triad is separate. It is this reason and those already mentioned that the COR is the responsibility of the requiring activity and...A. Fulghum, DoD Logistician Optimistic About Afghanistan (Aviation Week’s DTI , January 27, 2010) as reported on military.com, accessed on 15 February

  17. A 'new' psychological contract for nurses: some management implications.

    Science.gov (United States)

    Cavanagh, S J

    1996-03-01

    Changes within the health services are raising a number of employment issues for nurses. The idea that a professional qualification and a job will lead to security of employment and career development is rapidly changing. These assumptions, the 'old' psychological contract, is giving way to new expectations from employers and employees; the emergence of a 'new' psychological contract. A psychological contract is an implicit agreement between employer and employee that each party will treat the other fairly. Such contracts are maintained by virtue of all parties wanting to seek agreement on issues where possible and to maintain trust. While such a contract is not a legally binding agreement it is nonetheless a binding understanding between people. Changes to this psychological contract can have important implications for individuals and their employer in terms of work and organizational commitment. This paper will discuss some of the issues surrounding psychological contracts and the impact of violating them. It will also discuss, from a management perspective, how psychological contracts develop between employer and employee, and how to form a 'new' psychological contract based upon mutual benefit and shared values.

  18. Final Report on the Audit of the Administration of the Contract Closeout Process at the Defense Contract Management Region, Dallas

    Science.gov (United States)

    1990-09-18

    This is our final report on the Audit of the Administration of the Contract Closeout Process at the Defense Contract Management Region, Dallas (DCMR... audit was made from January to October 1989. The objectives of the audit were to determine the timeliness of the contract closeout process, the validity...As part of the audit , we also evaluated internal controls over the contract closeout process. As of December 31, 1988, the Contract Administration

  19. Effect of demand management on regulated and deregulated electricity sectors

    International Nuclear Information System (INIS)

    Fahrioglu, Murat

    2016-01-01

    Our society derives a quantifiable benefit from electric power. In particular, forced outages or blackouts have enormous consequences on society, one of which is loss of economic surplus. The society relies on having a continuous supply of electrical energy. Some customers may willingly risk this continuous supply and participate in demand management programs for electrical power. If the power system grid is in trouble, electric utilities need to have demand relief. Customers willing to reduce their demand to help the system can receive an incentive fee for helping the utilities. Demand relief can be system wide or location specific. Sometimes it can be more effective to fix the electrical demand vs. supply imbalance from the demand side. The value of demand management contracts is greatly affected by customer location. Inclusion of locational attributes into the contract design procedure increases the effectiveness of the contracts by helping a utility get more value from its demand management programs. Independent System Operators and regulators, among others, can also benefit from effective demand management. This paper will investigate how this type of demand management contracts can help the electricity sector both in regulated and deregulated environments. - Highlights: • Demand management can help prevent forced electricity outages. • Both electric utilities and ISOs can use demand management. • Regulated and deregulated electricity sectors can benefit from demand management. • Demand management contracts can be effectively used in power system grids.

  20. Regulatory body core competencies: when should a regulator contract a TSO?

    International Nuclear Information System (INIS)

    Wieland, Patricia; Salati de Almeida, Ivan P.; Almeida, Claudio U.; Costa, Eduardo M.

    2008-01-01

    The main nuclear regulatory functions are authorization, safety review and assessment, inspection and enforcement and development of regulations and guides. Additionally, the following supplementary functions may be executed by the regulatory body: research and development, emergency response and international cooperation. In order to function properly, the regulatory body should also have the following support functions: general management, logistics, training, communication and information, information technology support, institutional relationship, internal controls and audits, ombudsman and legal support. Technical Support Organizations (TSOs) may assist the regulatory body in meeting the challenges in a rapid growing and changing environment. Specially when there is a temporary need for a wider technical expertise diversity, short time to finish a project or when the cost of developing and maintaining infrastructure of their own laboratories for analysis and research is too high and may deviate the focus on the regulator's mission. Decision on the 'size' of the regulatory body and on what can be contracted to a Technical Support Organization (TSO) depends on the resources and capabilities needed to fulfil the regulatory functions efficiently. It is important to establish the core competencies that must be at the regulatory body, keeping the focus on the regulatory goals and define the real need to contract a TSO, weighting the benefits and disadvantages. As a contribution to the definition of the regulatory core competencies, the paper discusses what is essential to be kept at the regulatory body and what can be delegated to a TSO; how to manage and control the work of the TSO; the cost effectiveness of contracting, sharing of tacit knowledge; how to handle eventual conflicts between the parties involved in the licensing process; contract types and risk evaluation, concerning the dependence on a TSO, eventual change of partners and the intellectual capital

  1. Department of Energy contract/business management initiatives

    International Nuclear Information System (INIS)

    Fisher, S.B.

    1992-01-01

    More than 40 years ago the Department of Energy (DOE) developed a unique contractual instrument called a management and operating contract, to be used for the operation of our weapons production plants and the national laboratories. The contracts are very broad in scope. There is no output objective set forth in the contract. There are no cost targets, nor any contractually motivated cost objectives. Performance is measured against criteria which is often subjective. The time has come to make changes in the structure of these contracts to reflect changes in the work being performed and to make the contractors more accountable. DOE's work now, at these sites, and for years to come, consists largely of major project-type work such as environmental restoration which lends itself to a more definitized structure. DOE is in the process of implementing a work order authorization control system (task order contracting) under its management and operating contracts. Target date for implementation for our for-profit contractors is FY 1992, and for the non-profit contractors is FY 1993. Under this system, requirements will be contracted for as entities of work and contractors will be held accountable for performance, schedules and costs. Billings, payments and award fee will be tied to the specific planning objectives set forth in the tasks, including costs and schedules. Incentives will be provided for outstanding performance, fee may be withheld if performance is unacceptable. These changes will necessitate more DOE oversight of contractor operations and sound business support systems, as well as effective management disciplines. US DOE will perform business management reviews to assure contractors' systems are adequate and to support this form of contracting. The Contractor Procurement Systems Review Program will be enhanced to assure good subcontractor procurement practices

  2. Incentive Contracts and Hedge Fund Management

    OpenAIRE

    Jens Carsten Jackwerth; James E. Hodder

    2005-01-01

    This paper investigates dynamically optimal risk-taking by an expected-utility maximizing manager of a hedge fund. We examine the effects of variations on a compensation structure that includes a percentage management fee, a performance incentive for exceeding a specified highwater mark, and managerial ownership of fund shares. In our basic model, there is an exogenous liquidation barrier where the fund is shut down due to poor performance. We also consider extensions where the manager can vo...

  3. 25 CFR 533.2 - Time for submitting management contracts and amendments.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Time for submitting management contracts and amendments. 533.2 Section 533.2 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR MANAGEMENT CONTRACT PROVISIONS APPROVAL OF MANAGEMENT CONTRACTS § 533.2 Time for submitting management contracts and...

  4. 75 FR 50950 - Federal Speculative Position Limits for Referenced Energy Contracts and Associated Regulations

    Science.gov (United States)

    2010-08-18

    ..., section 4a(a) of the Act authorized the Commission to establish position limits for contracts traded on or... Position Limits for Referenced Energy Contracts and Associated Regulations AGENCY: Commodity Futures... and option contracts based on a limited set of exempt commodities,\\1\\ namely certain energy...

  5. 78 FR 48404 - Defense Federal Acquisition Regulation Supplement: Clauses With Alternates-Contract Financing...

    Science.gov (United States)

    2013-08-08

    ...-AI02 Defense Federal Acquisition Regulation Supplement: Clauses With Alternates--Contract Financing... Supplement (DFARS) to create an overarching prescription for the set of contract financing related clauses... amend the DFARS to create an overarching prescription for the contract financing clause with one...

  6. The Nuclear Regulator's Role in Assessing Licensee. Oversight of Vendor and Other Contracted Services

    International Nuclear Information System (INIS)

    2011-01-01

    Contracted services are an integral part of the design, construction and operation of a nuclear facility. Changes in the nuclear industry sector, including varied availability of nuclear expertise, the expansion of the international supply market and the introduction of new technologies, have tended to increase licensees' use of contracted services. These changes have created challenges for licensees and regulators related to the retention of nuclear expertise, the effective management of the interfaces between the licensees and contractors, and the oversight of contractor manufacturing quality in the context of greater multinational diversity. The regulatory body must address these challenges to provide assurance that the licensees maintain their responsibility for the safety of the facilities, regardless of who provides goods and services or where the activities involved in the supply chain take place. This report is intended to assist regulatory bodies in assessing their current practices for the regulatory oversight of licensees' use of contractors, and adapting them where necessary to meet the evolving situation

  7. Program management: The keys to a successful ERWM contract

    International Nuclear Information System (INIS)

    Lenyk, R.G.; Cusack, J.G.

    1995-01-01

    Program management for a large Environmental Restoration and Waste Management (ERWM) task order contract is both a skill and an art. Unlike project management, program management deals with global and political issues, with both client and home organizations, as well as with day-to-day operations. Program management requires up-front planning and nurturing, for no contract matures successfully by itself. This paper identifies the many opportunities presented in the planning and initial implementation of the contract. Potential traps are identified so that they can be recognized and avoided or mitigated. Teaming and subcontracting are also addressed. The authors rely on years of program management experience to explore such questions as the following: Can you have an integrated team? What needs to be done before you sign Your contract? Do you know who your client(s) is(are)? Have you incorporated the relevant, especially any new, procurement strategies? The US Department of Energy-Oak Ridge Operations (DOE-ORO) ERWM Remedial Design Contract with Foster Wheeler Environmental Corporation is used as a model for exploring these topics. This ERWM Program-which focuses on the Oak Ridge National Laboratory, the Y-12 Weapons Plant, and the K-25 Site in Oak Ridge, Tennessee; the Paducah Gaseous Diffusion Plant in Paducah, Kentucky; and the Portsmouth Gaseous Diffusion Plant in Portsmouth, Ohio-is in its fifth year with over 225 task orders. The program has been highly successful and has obtained from DOE outstanding marks for achieving quality, responsiveness, timeliness, and subcontracting goals

  8. Reengineering and health physics within the project Hanford management contract

    International Nuclear Information System (INIS)

    Atencio, E.M.

    1997-01-01

    The impending transition of the Hartford Site management and operations (M ampersand O) contract to a management and integrating (M ampersand I) contract format, together with weak radiological performance assessments by external organizations and reduced financial budgets prompted the 're-engineering' of the previous Hanford prime contractor Radiological Control (Rad Con) organization. This paper presents the methodology, identified areas of improvements, and results of the re-engineering process. The conversion from the M ampersand O to the M ampersand I contract concept resulted in multiple independent Rad Con organizations reporting to separate major contractors who are managed by an integrating contractor. This brought significant challenges when establishing minimum site standards for sitewide consistency, developing roles and responsibilities, and maintaining site Rad Con goals. Championed by the previous contractor's Rad Con Director, Denny Newland, a five month planning effort was executed to address the challenges of the M ampersand I and to address identified weaknesses. Fluor Daniel Hanford assumed the responsibility as integrator of the Project Hanford Management Contract on October 1, 1996. The Fluor Daniel Hanford Radiation Protection Director Jeff Foster presents the results of the re-engineering effort, including the significant cost savings, process improvements, field support improvements, and clarification of roles and responsibilities that have been achieved

  9. Management of Liquidity Risk Using Foreign Exchange Swap Contracts

    Directory of Open Access Journals (Sweden)

    Ivica Prga

    2009-12-01

    Full Text Available Croatian banks, like the other world banks, are exposed to liquidity risk. This is very significant question to them, particularly in this complex and crisis time. Therefore, the Croatian banks pay much attention to the management of liquidity. In these attempts, the banks use various derivative financial instruments of which the foreign exchange swap contracts are particularly remarkable.

  10. The older, the better! Age-related differences in emotion regulation after psychological contract breach.

    NARCIS (Netherlands)

    Bal, P.M.; Smit, P.

    2012-01-01

    The aim of this paper was to investigate the role of emotion regulation and age in reactions to psychological contract breach towards positive and negative affect. The authors expected that in the context of contract breach, reappraisal emotion regulation mitigate the negative relation with affect.

  11. Rac1 is a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

    DEFF Research Database (Denmark)

    Sylow, Lykke; Jensen, Thomas Elbenhardt; Kleinert, Maximilian

    2013-01-01

    In skeletal muscle, the actin cytoskeleton-regulating GTPase, Rac1, is necessary for insulin-dependent GLUT4 translocation. Muscle contraction increases glucose transport and represents an alternative signaling pathway to insulin. Whether Rac1 is activated by muscle contraction and regulates...

  12. The design of optimal electric power demand management contracts

    Science.gov (United States)

    Fahrioglu, Murat

    1999-11-01

    Our society derives a quantifiable benefit from electric power. In particular, forced outages or blackouts have enormous consequences on society, one of which is loss of economic surplus. Electric utilities try to provide reliable supply of electric power to their customers. Maximum customer benefit derives from minimum cost and sufficient supply availability. Customers willing to share in "availability risk" can derive further benefit by participating in controlled outage programs. Specifically, whenever utilities foresee dangerous loading patterns, there is a need for a rapid reduction in demand either system-wide or at specific locations. The utility needs to get relief in order to solve its problems quickly and efficiently. This relief can come from customers who agree to curtail their loads upon request in exchange for an incentive fee. This thesis shows how utilities can get efficient load relief while maximizing their economic benefit. This work also shows how estimated customer cost functions can be calibrated, using existing utility data, to help in designing efficient demand management contracts. In order to design such contracts, optimal mechanism design is adopted from "Game Theory" and applied to the interaction between a utility and its customers. The idea behind mechanism design is to design an incentive structure that encourages customers to sign up for the right contract and reveal their true value of power. If a utility has demand management contracts with customers at critical locations, most operational problems can be solved efficiently. This thesis illustrates how locational attributes of customers incorporated into demand management contract design can have a significant impact in solving system problems. This kind of demand management contracts can also be used by an Independent System Operator (ISO). During times of congestion a loss of economic surplus occurs. When the market is too slow or cannot help relieve congestion, demand management

  13. 78 FR 80369 - Federal Acquisition Regulation; Service Contracts Reporting Requirements

    Science.gov (United States)

    2013-12-31

    ... (e.g., cost-reimbursement, time-and- materials, and labor-hour contracts), which already require... contract costs and labor can significantly fluctuate each year or how this type of labor can be comingled... of direct labor hours expended on the services performed is extremely concerning, particularly in a...

  14. Electricity market risk management using forward contracts with bilateral options

    International Nuclear Information System (INIS)

    Chung, T.S.; Yu, C.W.; Wong, K.P.; Zhang, S.H.

    2003-01-01

    Extreme short-term price volatility in competitive electricity markets creates the need for risk management arrangements. A new electricity forward contract with bilateral financial options is introduced, which allows both seller and buyer to take advantage of flexibility in generation and consumption to obtain monetary benefits while simultaneously removing the risk of market price fluctuations. The option theory is incorporated to formulate the contract price. The strike prices of options are derived from solving an equilibrium model in which both the buyer and the seller aim to maximise their own profit. Theoretical analysis shows that the proposed optional forward contract presents a more equitable and reasonable payoff structure that allows the buyer and seller to earn a larger overall expected benefit, and the contractual arrangement supports efficiency in economic dispatch of electricity production and consumption. The insights obtained from these results will be helpful to participants in the contractual decision-making process. (Author)

  15. 48 CFR 935.071 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 935.071... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 935.071 Contract clause. The contracting officer must insert the clause at 952.235-71, Research Misconduct, in contracts, including management and operating...

  16. A Contract That Manages Itself: The Time Has Arrived

    Science.gov (United States)

    2015-02-01

    technology inspires contracting. The Smart Contract The paradigm of a contract as a static document is about to change. The days of a contract being read...efficiency is of paramount importance in order for an organization to perform its mission. The Smart Contract as an Object In discussions about...the contract object ( smart contract ) exists, the contract will be able to interact with other objects. That will enable the contract to know how

  17. Chloride regulates afferent arteriolar contraction in response to depolarization

    DEFF Research Database (Denmark)

    Hansen, P B; Jensen, B L; Skott, O

    1998-01-01

    -Renal vascular reactivity is influenced by the level of dietary salt intake. Recent in vitro data suggest that afferent arteriolar contractility is modulated by extracellular chloride. In the present study, we assessed the influence of chloride on K+-induced contraction in isolated perfused rabbit...... afferent arterioles. In 70% of vessels examined, K+-induced contraction was abolished by acute substitution of bath chloride. Consecutive addition of Cl- (30, 60, 80, 100, 110, and 117 mmol/L) restored the sensitivity to K+, and half-maximal response was observed at 82 mmol/L chloride. The calcium channel...... antagonist diltiazem (10(-6) mol/L) abolished K+-induced contractions. Bicarbonate did not modify the sensitivity to chloride. Norepinephrine (10(-6) mol/L) induced full contraction in depolarized vessels even in the absence of chloride. Iodide and nitrate were substituted for chloride with no inhibitory...

  18. 48 CFR 970.1504 - Contract pricing.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract pricing. 970.1504 Section 970.1504 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Contracting by Negotiation 970.1504 Contract pricing. ...

  19. Financial Management: Contracts Classified as Unreconcilable by the Defense Finance and Accounting Service Columbus (Contract No. F30602-81-C-0153)

    National Research Council Canada - National Science Library

    Granetto, Paul J; Kornides, James L; Issel, John K; Knight, Clarence E., III; Bennett, Karen M

    2005-01-01

    .... The Defense Contract Management Agency (DCMA) office in Orlando, Florida, administered the contract until October 7, 1985, when the responsibility for contract administration was transferred to the DCMA office in Palm Bay, Florida...

  20. Development of waste management regulations

    International Nuclear Information System (INIS)

    Elnour, E.G.

    2012-04-01

    Radioactive wastes are generated during nuclear fuel cycle operation, production and application of radioisotope in medicine, industry, research, and agriculture, and as a by product of natural resource exploitation, which includes mining and processing of ores. To ensure the protection of human health and the environment from the hazard of these wastes, a planned integrated radioactive waste management practice should be applied. The purpose of this study is to develop regulations for radioactive waste management for low and intermediate radioactive level waste (LILW), and other purpose of regulations is to establish requirements with which all organizations must comply in Sudan from LILW in particular disused/spent sources, not including radioactive waste for milling and mining practices. The national regulations regarding the radioactive waste management, should prescribe the allocation of responsibilities and roles of the Country, the regulatory body, user/owner, waste management organization, including regulations on transport packaging of waste and applied a quality assurance programme, to ensure that radioactive waste management is done safely and securely. (author)

  1. Rac1 is a novel regulator of contraction-stimulated glucose uptake in skeletal muscle.

    Science.gov (United States)

    Sylow, Lykke; Jensen, Thomas E; Kleinert, Maximilian; Mouatt, Joshua R; Maarbjerg, Stine J; Jeppesen, Jacob; Prats, Clara; Chiu, Tim T; Boguslavsky, Shlomit; Klip, Amira; Schjerling, Peter; Richter, Erik A

    2013-04-01

    In skeletal muscle, the actin cytoskeleton-regulating GTPase, Rac1, is necessary for insulin-dependent GLUT4 translocation. Muscle contraction increases glucose transport and represents an alternative signaling pathway to insulin. Whether Rac1 is activated by muscle contraction and regulates contraction-induced glucose uptake is unknown. Therefore, we studied the effects of in vivo exercise and ex vivo muscle contractions on Rac1 signaling and its regulatory role in glucose uptake in mice and humans. Muscle Rac1-GTP binding was increased after exercise in mice (~60-100%) and humans (~40%), and this activation was AMP-activated protein kinase independent. Rac1 inhibition reduced contraction-stimulated glucose uptake in mouse muscle by 55% in soleus and by 20-58% in extensor digitorum longus (EDL; P contraction-stimulated increment in glucose uptake was decreased by 27% (P = 0.1) and 40% (P muscles, respectively, of muscle-specific inducible Rac1 knockout mice. Furthermore, depolymerization of the actin cytoskeleton decreased contraction-stimulated glucose uptake by 100% and 62% (P muscles, respectively. These are the first data to show that Rac1 is activated during muscle contraction in murine and human skeletal muscle and suggest that Rac1 and possibly the actin cytoskeleton are novel regulators of contraction-stimulated glucose uptake.

  2. Radioactive waste management and regulation

    International Nuclear Information System (INIS)

    Willrich, M.

    1976-12-01

    The following conclusions are reached: (1) safe management of post-fission radioactive waste is already a present necessity and an irreversible long-term commitment; (2) basic goals of U.S. radioactive waste policy are unclear; (3) the existing organization for radioactive waste management is likely to be unworkable if left unchanged; and (4) the existing framework for radioactive waste regulation is likely to be ineffective if left unchanged

  3. Regulation of GPCR-mediated smooth muscle contraction : implications for asthma and pulmonary hypertension

    NARCIS (Netherlands)

    Wright, D B; Tripathi, S; Sikarwar, A; Santosh, K T; Perez-Zoghbi, J; Ojo, O O; Irechukwu, N; Ward, J P T; Schaafsma, D

    Contractile G-protein-coupled receptors (GPCRs) have emerged as key regulators of smooth muscle contraction, both under healthy and diseased conditions. This brief review will discuss some key topics and novel insights regarding GPCR-mediated airway and vascular smooth muscle contraction as

  4. 48 CFR 970.2210 - Service Contract Act.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Service Contract Act. 970... REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Application of Labor Policies 970.2210 Service Contract Act. The Service Contract Act of 1965 is not applicable to contracts for the management and operation of...

  5. Defense Contract Management: DOD's Lack of Adherence to Key Contracting Principles on Iraq Oil Contract Put Government Interests at Risk

    National Research Council Canada - National Science Library

    Hutton, John P; Ahearn, Marie; Augustine, Penny B; Campbell, Greg; James, Jr., Arthur; Lesonsky, Eric; Lord, Stephen; McDonough-Hughes, Anne; McKelvey, Janet; Patton, Kenneth

    2007-01-01

    .... The contract was also used to ensure adequate fuel supplies inside Iraq. RIO I was a cost-plus-award-fee type contract that provided for payment of the contractor's costs, a fixed fee determined at inception of the contract, and a potential award fee...

  6. Life-Cycle Based Climate Regulation Through Supply Chain Contracts

    DEFF Research Database (Denmark)

    Mitkidis, Katerina

    question thus arises what can we do to reduce emissions in global supply chains without having a clear knowledge on their distribution among the supply chain tiers. The paper proposes that commercial contracting can be a viable tool. It provides a brief theoretical account for, some empirical evidence...

  7. Debt Contracts, Collapse and Regulation as Competition Phenomena

    NARCIS (Netherlands)

    Gersbach, H.; Uhlig, H.F.H.V.S.

    1998-01-01

    We study a credit market with adverse selection and moral hazard where sufficient sorting is impossible. The crucial novel feature is the competition between lenders in their choice of contracts offered. Qualities of investment projects are not observable by banks and investment decisions of

  8. 76 FR 73564 - Federal Acquisition Regulation; Updates to Contract Reporting and Central Contractor Registration

    Science.gov (United States)

    2011-11-29

    ... Federal Acquisition Regulation; Updates to Contract Reporting and Central Contractor Registration AGENCIES... Procurement Data System (FPDS). Additionally, changes are proposed for the clauses requiring contractor registration in the Central Contractor Registration (CCR) database and DUNS number reporting. DATES: Interested...

  9. Contract Management of LHC Civil Engineering at Point 5

    CERN Document Server

    Osborne, J A

    1999-01-01

    Civil engineering work commenced in August 1998 at LEP Point 5 for the underground and surface works necessary to accommodate the CMS detector for the LHC project. The principal underground works consist of two parallel caverns, separated by a support pillar, two new shafts, a number of smaller connection and service galleries and tunnel enlargements on the existing LEP tunnel. The surface works consist of the 140 m long SX building for the detector assembly and numerous other steel and concrete structures necessary for the installation and operation of CMS. The civil engineering design and supervision has been awarded to a joint venture of Gibb (UK), SGI (Switzerland) and Geoconsult (Austria), and the contracting to a joint venture of Dragados (Spain) and Seli (Italy) for 112 MCHF. The aim of this paper is to discuss the management of this contract and in particular how the various parties interact in order to work most efficiently.

  10. Managing Reputation in Contract-Based Distributed Systems

    Science.gov (United States)

    Baldoni, Roberto; Doria, Luca; Lodi, Giorgia; Querzoni, Leonardo

    In industry practice, bilateral agreements are established between providers and consumers of services in order to regulate their business relationships. In particular, Quality of Service (QoS) requirements are specified in those agreements in the form of legally binding contracts named Service Level Agreements (SLA). Meeting SLAs allows providers to be seen in the eyes of their clients, credible, reliable, and trustworthy. This contributes to augment their reputation that can be considered an important and competitive advantage for creating potentially new business opportunities.

  11. Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle

    Science.gov (United States)

    Sylow, Lykke; Jensen, Thomas E.; Kleinert, Maximilian; Mouatt, Joshua R.; Maarbjerg, Stine J.; Jeppesen, Jacob; Prats, Clara; Chiu, Tim T.; Boguslavsky, Shlomit; Klip, Amira; Schjerling, Peter; Richter, Erik A.

    2013-01-01

    In skeletal muscle, the actin cytoskeleton-regulating GTPase, Rac1, is necessary for insulin-dependent GLUT4 translocation. Muscle contraction increases glucose transport and represents an alternative signaling pathway to insulin. Whether Rac1 is activated by muscle contraction and regulates contraction-induced glucose uptake is unknown. Therefore, we studied the effects of in vivo exercise and ex vivo muscle contractions on Rac1 signaling and its regulatory role in glucose uptake in mice and humans. Muscle Rac1-GTP binding was increased after exercise in mice (∼60–100%) and humans (∼40%), and this activation was AMP-activated protein kinase independent. Rac1 inhibition reduced contraction-stimulated glucose uptake in mouse muscle by 55% in soleus and by 20–58% in extensor digitorum longus (EDL; P Rac1 knockout mice. Furthermore, depolymerization of the actin cytoskeleton decreased contraction-stimulated glucose uptake by 100% and 62% (P Rac1 is activated during muscle contraction in murine and human skeletal muscle and suggest that Rac1 and possibly the actin cytoskeleton are novel regulators of contraction-stimulated glucose uptake. PMID:23274900

  12. 3-OST-7 regulates BMP-dependent cardiac contraction.

    Directory of Open Access Journals (Sweden)

    Shiela C Samson

    2013-12-01

    Full Text Available The 3-O-sulfotransferase (3-OST family catalyzes rare modifications of glycosaminoglycan chains on heparan sulfate proteoglycans, yet their biological functions are largely unknown. Knockdown of 3-OST-7 in zebrafish uncouples cardiac ventricular contraction from normal calcium cycling and electrophysiology by reducing tropomyosin4 (tpm4 expression. Normal 3-OST-7 activity prevents the expansion of BMP signaling into ventricular myocytes, and ectopic activation of BMP mimics the ventricular noncontraction phenotype seen in 3-OST-7 depleted embryos. In 3-OST-7 morphants, ventricular contraction can be rescued by overexpression of tropomyosin tpm4 but not by troponin tnnt2, indicating that tpm4 serves as a lynchpin for ventricular sarcomere organization downstream of 3-OST-7. Contraction can be rescued by expression of 3-OST-7 in endocardium, or by genetic loss of bmp4. Strikingly, BMP misregulation seen in 3-OST-7 morphants also occurs in multiple cardiac noncontraction models, including potassium voltage-gated channel gene, kcnh2, affected in Romano-Ward syndrome and long-QT syndrome, and cardiac troponin T gene, tnnt2, affected in human cardiomyopathies. Together these results reveal 3-OST-7 as a key component of a novel pathway that constrains BMP signaling from ventricular myocytes, coordinates sarcomere assembly, and promotes cardiac contractile function.

  13. Contract Labour (Regulation and Abolition) Act 1970 and labour market flexibility: An exploratory assessment of contract labour use in India's formal manufacturing

    OpenAIRE

    Das, Deb Kusum; Choudhury, Homagni; Singh, Jaivir

    2015-01-01

    One particularly significant piece of labour legislation in India is the Contract Labour (Regulation and Abolition) Act, 1970 (CLA,1970), which regulates labour hired by firms through the offices of a labour contractor - such labour being referred to as 'contract' labour in India. This paper seeks to examine this Act and its implication for manufacturing employment in India. While empirical evidence seems to indicate the presence of large number of 'contract' workers in the Indian manufacturi...

  14. Managing the relational character of public-private partnership contracts

    OpenAIRE

    Cvetković, Predrag

    2015-01-01

    A public-private partnership contract has the character of a relational contract. Relational contracts are incomplete agreements governing transactions where the contracting parties have mutually agreed that it is impossible or economically inefficient to contractually define ex ante possible difficulties and contingencies in the contract implementation, nor the difficulties and contingencies underlying the ex post control of contract performance by a third entity (court or arbitration). Cons...

  15. Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK.

    Science.gov (United States)

    Merry, Troy L; Steinberg, Gregory R; Lynch, Gordon S; McConell, Glenn K

    2010-03-01

    Reactive oxygen species (ROS) and nitric oxide (NO) have been implicated in the regulation of skeletal muscle glucose uptake during contraction, and there is evidence that they do so via interaction with AMP-activated protein kinase (AMPK). In this study, we tested the hypothesis that ROS and NO regulate skeletal muscle glucose uptake during contraction via an AMPK-independent mechanism. Isolated extensor digitorum longus (EDL) and soleus muscles from mice that expressed a muscle-specific kinase dead AMPKalpha2 isoform (AMPK-KD) and wild-type litter mates (WT) were stimulated to contract, and glucose uptake was measured in the presence or absence of the antioxidant N-acetyl-l-cysteine (NAC) or the nitric oxide synthase (NOS) inhibitor N(G)-monomethyl-l-arginine (l-NMMA). Contraction increased AMPKalpha2 activity in WT but not AMPK-KD EDL muscles. However, contraction increased glucose uptake in the EDL and soleus muscles of AMPK-KD and WT mice to a similar extent. In EDL muscles, NAC and l-NMMA prevented contraction-stimulated increases in oxidant levels (dichloroflourescein fluorescence) and NOS activity, respectively, and attenuated contraction-stimulated glucose uptake in both genotypes to a similar extent. In soleus muscles of AMPK-KD and WT mice, NAC prevented contraction-stimulated glucose uptake and l-NMMA had no effect. This is likely attributed to the relative lack of neuronal NOS in the soleus muscles compared with EDL muscles. Contraction increased AMPKalpha Thr(172) phosphorylation in EDL and soleus muscles of WT but not AMPK-KD mice, and this was not affected by NAC or l-NMMA treatment. In conclusion, ROS and NO are involved in regulating skeletal muscle glucose uptake during contraction via an AMPK-independent mechanism.

  16. Government Health Care Contract Incentives: Making Managed Health Care Work in Federal Government Procurements

    National Research Council Canada - National Science Library

    Teskey, Mark S

    1999-01-01

    Contracting for managed health care systems is a complex undertaking. The current TRICARE contracts captured all the important parts of the system and ensured detailed compliance with the many system requirements...

  17. 48 CFR 46.314 - Transportation contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Transportation contracts... MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.314 Transportation contracts. The contracting officer shall insert the clause at 52.246-14, Inspection of Transportation, in solicitations and contracts for freight...

  18. Regulation of radioactive waste management

    International Nuclear Information System (INIS)

    2002-01-01

    This bulletin contains information about activities of the Nuclear Regulatory Authority of the Slovak Republic (UJD). In this leaflet the regulation of radioactive waste management of the UJD are presented. Radioactive waste (RAW) is the gaseous, liquid or solid material that contains or is contaminated with radionuclides at concentrations or activities greater than clearance levels and for which no use is foreseen. The classification of radioactive waste on the basis of type and activity level is: - transition waste; - short lived low and intermediate level waste (LlLW-SL); - long lived low and intermediate level waste (LlLW-LL); - high level waste. Waste management (in accordance with Act 130/98 Coll.) involves collection, sorting, treatment, conditioning, transport and disposal of radioactive waste originated by nuclear facilities and conditioning, transport to repository and disposal of other radioactive waste (originated during medical, research and industrial use of radioactive sources). The final goal of radioactive waste management is RAW isolation using a system of engineered and natural barriers to protect population and environment. Nuclear Regulatory Authority of the Slovak Republic regulates radioactive waste management in accordance with Act 130/98 Coll. Inspectors regularly inspect and evaluate how the requirements for nuclear safety at nuclear facilities are fulfilled. On the basis of safety documentation evaluation, UJD issued permission for operation of four radioactive waste management facilities. Nuclear facility 'Technologies for treatment and conditioning contains bituminization plants and Bohunice conditioning centre with sorting, fragmentation, evaporation, incineration, supercompaction and cementation. Final product is waste package (Fibre reinforced container with solidified waste) acceptable for near surface repository in Mochovce. Republic repository in Mochovce is built for disposal of short lived low and intermediate level waste. Next

  19. Managing the training process: contracting for training services

    International Nuclear Information System (INIS)

    Carlson, E.R.

    1985-01-01

    The need for using consultants and contracting for training services should be based on one or more of these three major reasons: the need to expand capability on a crash basis, the need for specialized expertise, and the need for objectivity, and independence. When the need for using a consultant exists, the training manager must first define the scope of work or services the consultant is to provide and how the consultant will interface with the training staff. The next step will be to develop a Request for Proposal which involves management, training staff, and contract services organizations. The critical parts of an RFP are scope and schedule. Consideration would be given to determining which consultant organizations should receive the RFP, and specifying who is on the bidders list. The third step will consist of evaluating the proposals and awarding the work. This step needs to be objective, defendable, and repeatable. The final phase will be the performance of the work. The activities included are project initiation, monitoring contractor performance, and formal conclusion

  20. Rac1--a novel regulator of contraction-stimulated glucose uptake in skeletal muscle.

    Science.gov (United States)

    Sylow, Lykke; Møller, Lisbeth L V; Kleinert, Maximilian; Richter, Erik A; Jensen, Thomas E

    2014-12-01

    Muscle contraction stimulates muscle glucose uptake by facilitating translocation of glucose transporter 4 from intracellular locations to the cell surface, which allows for diffusion of glucose into the myofibres. The intracellular mechanisms regulating this process are not well understood. The GTPase Rac1 has, until recently, been investigated only with regard to its involvement in insulin-stimulated glucose uptake. However, we recently found that Rac1 is activated during muscle contraction and exercise in mice and humans. Remarkably, Rac1 seems to be necessary for exercise and contraction-stimulated glucose uptake in skeletal muscle, because muscle-specific Rac1 knockout mice display reduced ex vivo contraction- and in vivo exercise-stimulated glucose uptake. The molecular mechanism by which Rac1 regulates glucose uptake is presently unknown. However, recent studies link Rac1 to the actin cytoskeleton, the small GTPase RalA and/or free radical production, which have previously been shown to be regulators of glucose uptake in muscle. We propose a model in which Rac1 is activated by contraction- and exercise-induced mechanical stress signals and that Rac1 in conjunction with other signalling regulates glucose uptake during muscle contraction and exercise. © 2014 The Authors. Experimental Physiology © 2014 The Physiological Society.

  1. Standard contract terms regulation in the proposal for a common European sales law

    NARCIS (Netherlands)

    Loos, M.B.M.

    2012-01-01

    In this paper, the regulation in standard contract terms in the proposal for a Commono European Sales Law (CESL) is compared with the regulation in the Unfair Terms Directive, the Draft Common Frame of Reference (DCFR) and the Vienna Sales Convention (CISG). The paper starts with an overview of the

  2. 48 CFR 745.106 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 745.106 Section 745.106 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 745.106 Contract clauses. (a) The contracting officer shall insert the...

  3. 48 CFR 846.710 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 846.710 Section 846.710 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 846.710 Contract clauses. The contracting officer shall insert the clause at...

  4. 48 CFR 747.507 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 747.507 Section 747.507 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT TRANSPORTATION Ocean Transportation by U.S.-Flag Vessels 747.507 Contract clauses. Contracting...

  5. 48 CFR 947.7002 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 947.7002 Section 947.7002 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACT MANAGEMENT TRANSPORTATION Foreign Travel 947.7002 Contract clause. When foreign travel may be required under the contract...

  6. Regulation of Blood Flow in Contracting Skeletal Muscle in Aging

    DEFF Research Database (Denmark)

    Piil, Peter Bergmann

    Oxygen delivery to skeletal muscle is regulated precisely to match the oxygen demand; however, with aging the regulation of oxygen delivery during exercise is impaired. The present thesis investigated mechanisms underlying the age-related impairment in regulation of blood flow and oxygen delivery......GMP) was used as intervention, and skeletal muscle blood flow, oxygen delivery, and functional sympatholysis was examined. The two studies included 53 healthy, habitually active, male subjects. All subjects participated in an experimental day in which femoral arterial blood flow and blood pressure were assessed...... that improving sympatholytic capacity by training may be a slower process in older than in young men. In conclusion, this thesis provides new important knowledge related to the regulation of skeletal muscle blood flow in aging. Specifically, it demonstrates that changes in cGMP signaling is an underlying cause...

  7. Effects of adenosine triphosphate concentration on motor force regulation during skeletal muscle contraction

    Science.gov (United States)

    Wei, J.; Dong, C.; Chen, B.

    2017-04-01

    We employ a mechanical model of sarcomere to quantitatively investigate how adenosine triphosphate (ATP) concentration affects motor force regulation during skeletal muscle contraction. Our simulation indicates that there can be negative cross-bridges resisting contraction within the sarcomere and higher ATP concentration would decrease the resistance force from negative cross-bridges by promoting their timely detachment. It is revealed that the motor force is well regulated only when ATP concentration is above a certain level. These predictions may provide insights into the role of ATP in regulating coordination among multiple motors.

  8. THE REGULATION OF THE BANKING CONTRACTS IN THE NEW CIVIL CODE

    Directory of Open Access Journals (Sweden)

    George Chiocaru

    2012-11-01

    Full Text Available Starting with the enactment of the New Civil Code have been regulated for the first time contracts and legal institutions specific to the banking activity. The new regulation even if they brought important solutions for certain problems regarded in the commercial activity and especially in the banking sector, have also raised new questions regarding especially their domain of applicability, their imperative or dispositive character or the possibility for the parties to conclude contract other than those expressly regulated. By taking into consideration the special character of the operations involving the administration of money as well as the sensitivity from a legal and especially social perspective of the ownership relation regarding money, we have focused in our analysis on the relations resulting from the contracts regulated by the chapter “the bank account and other banking contracts”

  9. Committing to coal and gas: Long-term contracts, regulation, and fuel switching in power generation

    Science.gov (United States)

    Rice, Michael

    Fuel switching in the electricity sector has important economic and environmental consequences. In the United States, the increased supply of gas during the last decade has led to substantial switching in the short term. Fuel switching is constrained, however, by the existing infrastructure. The power generation infrastructure, in turn, represents commitments to specific sources of energy over the long term. This dissertation explores fuel contracts as the link between short-term price response and long-term plant investments. Contracting choices enable power plant investments that are relationship-specific, often regulated, and face uncertainty. Many power plants are subject to both hold-up in investment and cost-of-service regulation. I find that capital bias is robust when considering either irreversibility or hold-up due to the uncertain arrival of an outside option. For sunk capital, the rental rate is inappropriate for determining capital bias. Instead, capital bias depends on the regulated rate of return, discount rate, and depreciation schedule. If policies such as emissions regulations increase fuel-switching flexibility, this can lead to capital bias. Cost-of-service regulation can shorten the duration of a long-term contract. From the firm's perspective, the existing literature provides limited guidance when bargaining and writing contracts for fuel procurement. I develop a stochastic programming framework to optimize long-term contracting decisions under both endogenous and exogenous sources of hold-up risk. These typically include policy changes, price shocks, availability of fuel, and volatility in derived demand. For price risks, the optimal contract duration is the moment when the expected benefits of the contract are just outweighed by the expected opportunity costs of remaining in the contract. I prove that imposing early renegotiation costs decreases contract duration. Finally, I provide an empirical approach to show how coal contracts can limit

  10. Integrin and GPCR Crosstalk in the Regulation of ASM Contraction Signaling in Asthma.

    Science.gov (United States)

    Teoh, Chun Ming; Tam, John Kit Chung; Tran, Thai

    2012-01-01

    Airway hyperresponsiveness (AHR) is one of the cardinal features of asthma. Contraction of airway smooth muscle (ASM) cells that line the airway wall is thought to influence aspects of AHR, resulting in excessive narrowing or occlusion of the airway. ASM contraction is primarily controlled by agonists that bind G protein-coupled receptor (GPCR), which are expressed on ASM. Integrins also play a role in regulating ASM contraction signaling. As therapies for asthma are based on symptom relief, better understanding of the crosstalk between GPCRs and integrins holds good promise for the design of more effective therapies that target the underlying cellular and molecular mechanism that governs AHR. In this paper, we will review current knowledge about integrins and GPCRs in their regulation of ASM contraction signaling and discuss the emerging concept of crosstalk between the two and the implication of this crosstalk on the development of agents that target AHR.

  11. Rac1- a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

    DEFF Research Database (Denmark)

    Sylow, Lykke; Møller, Lisbeth L V; Kleinert, Maximilian

    2014-01-01

    -stimulated glucose uptake in skeletal muscle, since muscle-specific Rac1 knockout mice display reduced ex vivo contraction- and in vivo exercise-stimulated glucose uptake in skeletal muscle. The molecular mechanisms by which Rac1 regulate glucose uptake is presently unknown. However, recent studies link Rac1......Muscle contraction stimulates muscle glucose uptake by facilitating translocation of the glucose transporter 4 from intracellular locations to the cell surface, which allows for diffusion of glucose into the myofibers. However, the intracellular mechanisms regulating this process are not well...... understood. The GTPase, Rac1 has, until recently, only been investigated with regards to its involvement in insulin-stimulated glucose uptake. However, we recently found that Rac1 is activated during muscle contraction and exercise in mice and humans. Remarkably, Rac1 seems to be necessary for exercise/contraction...

  12. Managing the risks associated with natural gas purchase contracts

    International Nuclear Information System (INIS)

    Brett, T.

    2003-01-01

    This presentation described different styles of gas contracts. When markets opened in 1986, many contracts were between end users and producers, and a few marketers. Typically, contracts were for a fixed price and term. In 1990, when gas futures contracts began trading on NYMEX, contracts began to have floating prices, and prices linked to NYMEX prices. Standard gas contracts were developed in the mid-late 1990s. This paper described the differences between plain retail gas contracts, retail gas contracts between mass marketers and end users, wholesale contracts, contracts between producers and marketers, transportation contracts and domestic contracts. Both contracting parties obtain business and legal advice from consultants and lawyers with knowledge in energy transactions. Master agreement contracts were also described with reference to the Gas EDI contract. Examples of changing regulatory requirements were also outlined along with some traps to avoid. Bundled transportation agreements are standard documents that can be negotiated in special circumstances to charge customers who fail to deliver. They should be considered as tariffs

  13. 77 FR 63805 - Federal Acquisition Regulation; Information Collection; Service Contracting

    Science.gov (United States)

    2012-10-17

    ... use of appropriate technological collection techniques or other forms of information technology. DATES... all correspondence related to this collection. All comments received will be posted without change to http://www.regulations.gov , including any personal and/or business confidential information provided...

  14. 48 CFR 970.1706-2 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.1706... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Special Contracting Methods 970.1706-2 Contract clause. The contracting officer shall insert the clause at 48 CFR 52.217-9, Option to Extend the Term of...

  15. 48 CFR 970.1707-4 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.1707... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Special Contracting Methods 970.1707-4 Contract clause. Insert the clause at 970.5217-1, Work for Others Program (Non-DOE Funded Work), in any contract...

  16. 48 CFR 942.270-2 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 942.270-2 Section 942.270-2 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Contract Administration Services 942.270-2 Contract clause. The clause at 952...

  17. 48 CFR 1631.205-74 - FEHBP losses on other contracts.

    Science.gov (United States)

    2010-10-01

    ... carry forward” principle that is fundamental to continuing insurance contracts that are based on... MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Commercial Organizations 1631.205-74 FEHBP losses on...

  18. Radioactive waste management and regulation

    International Nuclear Information System (INIS)

    Willrich, M.; Lester, R.K.; Greenberg, S.C.; Mitchell, H.C.; Walker, D.A.

    1977-01-01

    Purpose of this book is to assist in developing public policy and institutions for the safe management of radioactive waste, currently and long term. Both high-level waste and low-level waste containing transuranium elements are covered. The following conclusions are drawn: the safe management of post-fission radioactive waste is already a present necessity and an irreversible long-term commitment; the basic goals of U.S. radioactive waste policy are unclear; the existing organization for radioactive waste management is likely to be unworkable if left unchanged; and the existing framework for radioactive waste regulation is likely to be ineffective if left unchanged. The following recommendations are made: a national Radioactive Waste Authority should be established as a federally chartered public corporation; with NRC as the primary agency, a comprehensive regulatory framework should be established to assure the safety of all radioactive waste management operations under U.S. jurisdiction or control; ERDA should continue to have primary government responsibility for R and D and demonstration of radioactive waste technology; and the U.S. government should propose that an international Radioactive Waste Commission be established under the IAEA

  19. Best in Class Project Management and Contract Management Initiative at the Department of Energy's Office of Environmental Management

    International Nuclear Information System (INIS)

    Van Camp, S.G.; Stevenson, J.S.; Deiters, M.G.

    2009-01-01

    Since its founding in 1989, the U.S. Department of Energy (DOE), Office of Environmental Management (EM) has struggled with a legacy of inadequate project and contract management. This has been manifested in recurring scope changes, cost overruns and schedule delays, and has been documented in multiple internal and external reviews. To address this issue, EM has developed a vision for building a 'Best in Class' Project Management and Contract Management (BICPM) organization. To develop the strategy and implement the process to accomplish this vision, EM contracted with the U.S. Army Corps of Engineers (USACE) and their support contractors. EM and the USACE Team developed a five-phased approach to implement the BICPM Initiative: (I) develop assessment criteria, (II) assess existing project and contract management capabilities, (III) develop an implementation plan, (IV) implement corrective actions, and (V) institutionalize BICPM. Under Phases I and II, the USACE Team assessed the status of project and contract management capabilities at 16 EM offices. These assessments evaluated strengths and weaknesses in 12 key project management capabilities and benchmarks and three contract management benchmarks. Under Phase III, EM and the USACE Team developed the Corporate Implementation Plan which identified the key challenges and provided a road-map to address these challenges and to implement BICPM. These challenges included: Federal staffing shortages; integration of project and contract management; further development of project-oriented culture; project baseline maintenance; consistent implementation of the DOE order for project management, 413.3A; and role of EM Headquarters in BICPM. The shortage of qualified resources dedicated to supporting Federal project and contract management functions was identified as a primary cause for project and contract management difficulties within EM. The Corporate Implementation Plan outlined a set of 18 specific Recommended Priority

  20. Management of Contracts for F110 Engine Procurements

    National Research Council Canada - National Science Library

    Granetto, Paul

    2001-01-01

    This audit was performed in response to an allegation to the Defense Hotline that the Wright-Patterson Air Force Base Procurement Contracting Office made poor procurement decisions on F110 aircraft engine contracts...

  1. CaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle.

    Science.gov (United States)

    Witczak, Carol A; Jessen, Niels; Warro, Daniel M; Toyoda, Taro; Fujii, Nobuharu; Anderson, Mark E; Hirshman, Michael F; Goodyear, Laurie J

    2010-06-01

    Studies using chemical inhibitors have suggested that the Ca(2+)-sensitive serine/threonine kinase Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a key regulator of both insulin- and contraction-stimulated glucose uptake in skeletal muscle. However, due to nonspecificity of these inhibitors, the specific role that CaMKII may play in the regulation of glucose uptake is not known. We sought to determine whether specific inhibition of CaMKII impairs insulin- and/or contraction-induced glucose uptake in mouse skeletal muscle. Expression vectors containing green fluorescent protein conjugated to a CaMKII inhibitory (KKALHRQEAVDCL) or control (KKALHAQERVDCL) peptide were transfected into tibialis anterior muscles by in vivo electroporation. After 1 wk, muscles were assessed for peptide expression, CaMK activity, insulin- and contraction-induced 2-[(3)H]deoxyglucose uptake, glycogen concentrations, and changes in intracellular signaling proteins. Expression of the CaMKII inhibitory peptide decreased muscle CaMK activity approximately 35% compared with control peptide. Insulin-induced glucose uptake was not changed in muscles expressing the inhibitory peptide. In contrast, expression of the inhibitory peptide significantly decreased contraction-induced muscle glucose uptake (approximately 30%). Contraction-induced decreases in muscle glycogen were not altered by the inhibitory peptide. The CaMKII inhibitory peptide did not alter expression of the glucose transporter GLUT4 and did not impair contraction-induced increases in the phosphorylation of AMP-activated protein kinase (Thr(172)) or TBC1D1/TBC1D4 on phospho-Akt substrate sites. These results demonstrate that CaMKII does not regulate insulin-stimulated glucose uptake in skeletal muscle. However, CaMKII plays a critical role in the regulation of contraction-induced glucose uptake in mouse skeletal muscle.

  2. Differences in Services and Fees for Management and Administration of Iraq Reconstruction Contracts

    National Research Council Canada - National Science Library

    Warren, David; Childress, David; Salvatierra, George; Thompson, Chuck; Williams, Roger M

    2008-01-01

    ...), a field operating agency of the Air Force Civil Engineer, are two primary organizations providing project management and contract administration services for major Iraq reconstruction projects...

  3. Tank Operations Contract Construction Management Methodology. Utilizing The Agency Method Of Construction Management

    International Nuclear Information System (INIS)

    Lesko, K.F.; Berriochoa, M.V.

    2010-01-01

    Washington River Protection Solutions, LLC (WRPS) has faced significant project management challenges in managing Davis-Bacon construction work that meets contractually required small business goals. The unique challenge is to provide contracting opportunities to multiple small business constructioin subcontractors while performing high hazard work in a safe and productive manner. Previous to the WRPS contract, construction work at the Hanford Tank Farms was contracted to large companies, while current Department of Energy (DOE) Contracts typically emphasize small business awards. As an integral part of Nuclear Project Management at Hanford Tank Farms, construction involves removal of old equipment and structures and installation of new infrastructure to support waste retrieval and waste feed delivery to the Waste Treatment Plant. Utilizing the optimum construction approach ensures that the contractors responsible for this work are successful in meeting safety, quality, cost and schedule objectives while working in a very hazardous environment. This paper descirbes the successful transition from a traditional project delivery method that utilized a large business general contractor and subcontractors to a new project construction management model that is more oriented to small businesses. Construction has selected the Agency Construction Management Method (John E Schaufelberger, Len Holm, 'Management of Construction Projects, A Constructor's Perspective', University of Washington, Prentice Hall 2002). This method was implemented in the first quarter of Fiscal Year 2009 (FY2009), where Construction Management is performed by substantially home office resources from the URS Northwest Office in Richland, Washington. The Agency Method has allowed WRPS to provide proven Construction Managers and Field Leads to mentor and direct small business contractors, thus providing expertise and assurance of a successful project. Construction execution contracts are subcontracted

  4. TANK OPERATIONS CONTRACT CONSTRUCTION MANAGEMENT METHODOLOGY UTILIZING THE AGENCY METHOD OF CONSTRUCTION MANAGEMENT

    Energy Technology Data Exchange (ETDEWEB)

    LESKO KF; BERRIOCHOA MV

    2010-02-26

    Washington River Protection Solutions, LLC (WRPS) has faced significant project management challenges in managing Davis-Bacon construction work that meets contractually required small business goals. The unique challenge is to provide contracting opportunities to multiple small business constructioin subcontractors while performing high hazard work in a safe and productive manner. Previous to the WRPS contract, construction work at the Hanford Tank Farms was contracted to large companies, while current Department of Energy (DOE) Contracts typically emphasize small business awards. As an integral part of Nuclear Project Management at Hanford Tank Farms, construction involves removal of old equipment and structures and installation of new infrastructure to support waste retrieval and waste feed delivery to the Waste Treatment Plant. Utilizing the optimum construction approach ensures that the contractors responsible for this work are successful in meeting safety, quality, cost and schedule objectives while working in a very hazardous environment. This paper descirbes the successful transition from a traditional project delivery method that utilized a large business general contractor and subcontractors to a new project construction management model that is more oriented to small businesses. Construction has selected the Agency Construction Management Method (John E Schaufelberger, Len Holm, "Management of Construction Projects, A Constructor's Perspective", University of Washington, Prentice Hall 2002). This method was implemented in the first quarter of Fiscal Year 2009 (FY2009), where Construction Management is performed by substantially home office resources from the URS Northwest Office in Richland, Washington. The Agency Method has allowed WRPS to provide proven Construction Managers and Field Leads to mentor and direct small business contractors, thus providing expertise and assurance of a successful project. Construction execution contracts are

  5. 48 CFR 970.0470-2 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.0470... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Administrative Matters 970.0470-2 Contract clause. The contracting officer shall insert the clause at 970.5204-2, Laws, Regulations, and DOE...

  6. Contract Audit Followup: Defense Contract Management Agency Santa Ana Office's Actions on Incurred Cost Audits

    National Research Council Canada - National Science Library

    2005-01-01

    This report addresses the DCMA Santa Ana District Office. DoD Directive 7640.2, "Policy for Follow-up on Contract Audit Reports," February 12, 1988, as amended August 16, 1995, implements OMB Circular A-50...

  7. Financial Management: Reopening of Contracts in the Mechanization of Contract Administration Services System

    National Research Council Canada - National Science Library

    Granetto, Paul

    2003-01-01

    The Defense Finance and Accounting Service planned to replace the payment and entitlement function performed by the Mechanization of Contract Administration Services system with a new or modified system...

  8. 75 FR 26916 - Federal Acquisition Regulation: FAR Case 2009-004, Enhancing Contract Transparency

    Science.gov (United States)

    2010-05-13

    ... Regulation: FAR Case 2009-004, Enhancing Contract Transparency AGENCY: Department of Defense (DoD), General... commercial or financial information. This transparency effort is intended to promote efficiency in Government... the Administration's memorandum entitled Transparency and Open Government (January 21, 2009...

  9. 78 FR 37692 - Federal Acquisition Regulation; Contracting With Women-Owned Small Business Concerns

    Science.gov (United States)

    2013-06-21

    ...-AM59 Federal Acquisition Regulation; Contracting With Women-Owned Small Business Concerns AGENCY... disadvantaged women-owned small business concerns and to women-owned small business concerns eligible under the Women-owned Small Business Program. DATES: Effective Date: June 21, 2013. Comment Date: Interested...

  10. 77 FR 47797 - Federal Acquisition Regulation; Small Business Set Asides for Research and Development Contracts

    Science.gov (United States)

    2012-08-10

    ... Acquisition Regulation; Small Business Set Asides for Research and Development Contracts AGENCY: Department of... when the market research conducted in accordance with FAR part 10 indicates there are small businesses... officer can proceed with a small business set-aside for research and development. FAR 19.502-2(b...

  11. 75 FR 65566 - Revised Regulations Concerning Section 403(b) Tax-Sheltered Annuity Contracts; Correction

    Science.gov (United States)

    2010-10-26

    ... DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 [TD 9340] RIN 1545-BB64 Revised Regulations Concerning Section 403(b) Tax-Sheltered Annuity Contracts; Correction AGENCY: Internal Revenue... additional rules relating to annuities payable from a retirement income account. * * * * * 0 Par. 4. Section...

  12. 76 FR 76622 - Federal Management Regulation; Motor Vehicle Management

    Science.gov (United States)

    2011-12-08

    ...; Docket 2011-0011; Sequence 2] RIN 3090-AJ14 Federal Management Regulation; Motor Vehicle Management... Administration is amending the Federal Management Regulation (FMR) by revising current policy on the definitions... CONTACT: For clarification of content, contact Mr. James Vogelsinger, Director, Motor Vehicle Management...

  13. 76 FR 31545 - Federal Management Regulation; Motor Vehicle Management

    Science.gov (United States)

    2011-06-01

    ...; Sequence 1] RIN 3090-AJ14 Federal Management Regulation; Motor Vehicle Management AGENCY: Office of... Services Administration is proposing to amend the Federal Management Regulation (FMR) by revising current....C. 553(a)(2) because it applies to agency management. However, this proposed rule is being published...

  14. MANAGING ENGINEERING ACTIVITIES FOR THE PLATEAU REMEDIATION CONTRACT - HANFORD

    Energy Technology Data Exchange (ETDEWEB)

    KRONVALL CM

    2011-01-14

    In 2008, the primary Hanford clean-up contract transitioned to the CH2MHill Plateau Remediation Company (CHPRC). Prior to transition, Engineering resources assigned to remediation/Decontamination and Decommissioning (D&D) activities were a part of a centralized engineering organization and matrixed to the performing projects. Following transition, these resources were reassigned directly to the performing project, with a loose matrix through a smaller Central Engineering (CE) organization. The smaller (10 FTE) central organization has retained responsibility for the overall technical quality of engineering for the CHPRC, but no longer performs staffing and personnel functions. As the organization has matured, there are lessons learned that can be shared with other organizations going through or contemplating performing a similar change. Benefits that have been seen from the CHPRC CE organization structure include the following: (1) Staff are closely aligned with the 'Project/facility' that they are assigned to support; (2) Engineering priorities are managed to be consistent with the 'Project/facility' priorities; (3) Individual Engineering managers are accountable for identifying staffing needs and the filling of staffing positions; (4) Budget priorities are managed within the local organization structure; (5) Rather than being considered a 'functional' organization, engineering is considered a part of a line, direct funded organization; (6) The central engineering organization is able to provide 'overview' activities and maintain independence from the engineering organizations in the field; and (7) The central engineering organization is able to maintain a stable of specialized experts that are able to provide independent reviews of field projects and day-to-day activities.

  15. MANAGING ENGINEERING ACTIVITIES FOR THE PLATEAU REMEDIATION CONTRACT - HANFORD

    International Nuclear Information System (INIS)

    Kronvall, C.M.

    2011-01-01

    In 2008, the primary Hanford clean-up contract transitioned to the CH2MHill Plateau Remediation Company (CHPRC). Prior to transition, Engineering resources assigned to remediation/Decontamination and Decommissioning (D and D) activities were a part of a centralized engineering organization and matrixed to the performing projects. Following transition, these resources were reassigned directly to the performing project, with a loose matrix through a smaller Central Engineering (CE) organization. The smaller (10 FTE) central organization has retained responsibility for the overall technical quality of engineering for the CHPRC, but no longer performs staffing and personnel functions. As the organization has matured, there are lessons learned that can be shared with other organizations going through or contemplating performing a similar change. Benefits that have been seen from the CHPRC CE organization structure include the following: (1) Staff are closely aligned with the 'Project/facility' that they are assigned to support; (2) Engineering priorities are managed to be consistent with the 'Project/facility' priorities; (3) Individual Engineering managers are accountable for identifying staffing needs and the filling of staffing positions; (4) Budget priorities are managed within the local organization structure; (5) Rather than being considered a 'functional' organization, engineering is considered a part of a line, direct funded organization; (6) The central engineering organization is able to provide 'overview' activities and maintain independence from the engineering organizations in the field; and (7) The central engineering organization is able to maintain a stable of specialized experts that are able to provide independent reviews of field projects and day-to-day activities.

  16. Academic Health Systems Management: The Rationale Behind Capitated Contracts

    Science.gov (United States)

    Taheri, Paul A.; Butz, David A.; Greenfield, Lazar J.

    2000-01-01

    Objective To determine why hospitals enter into “capitated” contracts, which often generate accounting losses. The authors’ hypothesis is that hospitals coordinate contracts to keep beds full and that in principal, capitated contracts reflect sound capacity management. Summary Background Data In high-overhead industries, different consumers pay different prices for similar services (e.g., full-fare vs. advanced-purchase plane tickets, full tuition vs. financial aid). Some consumers gain access by paying less than total cost. Hospitals, like other high-overhead business enterprises, must optimize the use of their capacity, amortizing overhead over as many patients as possible. This necessity for enhanced throughput forces hospitals and health systems to discount empty beds, sometimes to the point where they incur accounting losses serving some payors. Methods The authors analyzed the cost accounting system at their university teaching hospital to compare hospital and intensive care unit (ICU) lengths of stay (LOS), variable direct costs (VDC), overhead of capitated patients, and reimbursement versus other payors for all hospital discharges (n = 29,036) in fiscal year 1998. The data were analyzed by diagnosis-related groups (DRGs), length of stay (LOS), insurance carrier, proximity to hospital, and discharge disposition. Patients were then distinguished across payor categories based on their resource utilization, proximity to the hospital, DRG, LOS, and discharge status. Results The mean cost for capitated patients was $4,887, less than half of the mean cost of $10,394 for the entire hospitalized population. The mean capitated reimbursement was $928/day, exceeding the mean daily VDC of $616 but not the total cost of $1,445/day. Moreover, the mean total cost per patient day of treating a capitated patient was $400 less than the mean total cost per day for noncapitated patients. The hospital’s capitated health maintenance organization (HMO) patients made up 16

  17. Academic health systems management: the rationale behind capitated contracts.

    Science.gov (United States)

    Taheri, P A; Butz, D A; Greenfield, L J

    2000-06-01

    To determine why hospitals enter into "capitated" contracts, which often generate accounting losses. The authors' hypothesis is that hospitals coordinate contracts to keep beds full and that in principal, capitated contracts reflect sound capacity management. In high-overhead industries, different consumers pay different prices for similar services (e.g., full-fare vs. advanced-purchase plane tickets, full tuition vs. financial aid). Some consumers gain access by paying less than total cost. Hospitals, like other high-overhead business enterprises, must optimize the use of their capacity, amortizing overhead over as many patients as possible. This necessity for enhanced throughput forces hospitals and health systems to discount empty beds, sometimes to the point where they incur accounting losses serving some payors. The authors analyzed the cost accounting system at their university teaching hospital to compare hospital and intensive care unit (ICU) lengths of stay (LOS), variable direct costs (VDC), overhead of capitated patients, and reimbursement versus other payors for all hospital discharges (n = 29,036) in fiscal year 1998. The data were analyzed by diagnosis-related groups (DRGs), length of stay (LOS), insurance carrier, proximity to hospital, and discharge disposition. Patients were then distinguished across payor categories based on their resource utilization, proximity to the hospital, DRG, LOS, and discharge status. The mean cost for capitated patients was $4,887, less than half of the mean cost of $10,394 for the entire hospitalized population. The mean capitated reimbursement was $928/day, exceeding the mean daily VDC of $616 but not the total cost of $1,445/day. Moreover, the mean total cost per patient day of treating a capitated patient was $400 less than the mean total cost per day for noncapitated patients. The hospital's capitated health maintenance organization (HMO) patients made up 16. 0% of the total admissions but only 9.4% of the total

  18. Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle.

    Science.gov (United States)

    Vichaiwong, Kanokwan; Purohit, Suneet; An, Ding; Toyoda, Taro; Jessen, Niels; Hirshman, Michael F; Goodyear, Laurie J

    2010-10-15

    TBC1D1 (tre-2/USP6, BUB2, cdc16 domain family member 1) is a Rab-GAP (GTPase-activating protein) that is highly expressed in skeletal muscle, but little is known about TBC1D1 regulation and function. We studied TBC1D1 phosphorylation on three predicted AMPK (AMP-activated protein kinase) phosphorylation sites (Ser231, Ser660 and Ser700) and one predicted Akt phosphorylation site (Thr590) in control mice, AMPKα2 inactive transgenic mice (AMPKα2i TG) and Akt2-knockout mice (Akt2 KO). Muscle contraction significantly increased TBC1D1 phosphorylation on Ser231 and Ser660, tended to increase Ser700 phosphorylation, but had no effect on Thr590. AICAR (5-aminoimidazole-4-carboxyamide ribonucleoside) also increased phosphorylation on Ser231, Ser660 and Ser700, but not Thr590, whereas insulin only increased Thr590 phosphorylation. Basal and contraction-stimulated TBC1D1 Ser231, Ser660 and Ser700 phosphorylation were greatly reduced in AMPKα2i TG mice, although contraction still elicited a small increase in phosphorylation. Akt2 KO mice had blunted insulin-stimulated TBC1D1 Thr590 phosphorylation. Contraction-stimulated TBC1D1 Ser231 and Ser660 phosphorylation were normal in high-fat-fed mice. Glucose uptake in vivo was significantly decreased in tibialis anterior muscles overexpressing TBC1D1 mutated on four predicted AMPK phosphorylation sites. In conclusion, contraction causes site-specific phosphorylation of TBC1D1 in skeletal muscle, and TBC1D1 phosphorylation on AMPK sites regulates contraction-stimulated glucose uptake. AMPK and Akt regulate TBC1D1 phosphorylation, but there must be additional upstream kinases that mediate TBC1D1 phosphorylation in skeletal muscle.

  19. Workup and management of patients with frequent premature ventricular contractions.

    Science.gov (United States)

    Giles, Katie; Green, Martin S

    2013-11-01

    Premature ventricular contractions (PVCs) are a frequently encountered entity in clinical cardiology. They rarely affect prognosis or management. However, they might produce bothersome symptoms and, in select individuals with a high PVC burden, they might contribute to left ventricular (LV) dysfunction. Workup of patients with very frequent PVCs consists of a thorough history and physical examination to screen for underlying cardiac disease and potential triggers. Routine investigations include a standard 12-lead electrocardiogram, as well as an echocardiogram. A Holter monitor should be performed in those with severe symptoms, a history of syncope, or a malignant family history. Exercise stress testing has a role in evaluating for ischemia and in the assessment of patients with exertional symptoms. More advanced testing is not warranted if these initial investigations are reassuring. Referral to an arrhythmia specialist should be considered in patients with LV dysfunction whose PVC burden exceeds 15%. Frequent ventricular ectopy represents a rare, but reversible cause of LV dysfunction and these patients should be further evaluated for possible catheter ablation. Copyright © 2013 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  20. 48 CFR 237.102-72 - Contracts for management services.

    Science.gov (United States)

    2010-10-01

    ... development or production of the major system ensures that Federal employees are responsible for determining— (1) Courses of action to be taken in the best interest of the Government; and (2) Best technical performance for the warfighter; and (c) The contract requires that the prime contractor for the contract may...

  1. 78 FR 34266 - Acquisition Regulations; Buy Indian Act; Procedures for Contracting

    Science.gov (United States)

    2013-06-07

    ... Indian ownership of business enterprises from a mandatory 100 percent to minimum 51 percent. In addition... earnings from the contract, and control management and daily business operations. To ensure actual control... primary industry in which the enterprise conducts business. b. Self-Certification Comment: A commenter...

  2. Rho Kinase (ROCK) collaborates with Pak to Regulate Actin Polymerization and Contraction in Airway Smooth Muscle.

    Science.gov (United States)

    Zhang, Wenwu; Bhetwal, Bhupal P; Gunst, Susan J

    2018-05-10

    The mechanisms by which Rho kinase (ROCK) regulates airway smooth muscle contraction were determined in tracheal smooth muscle tissues. ROCK may mediate smooth muscle contraction by inhibiting myosin regulatory light chain (RLC) phosphatase. ROCK can also regulate F-actin dynamics during cell migration, and actin polymerization is critical for airway smooth muscle contraction. Our results show that ROCK does not regulate airway smooth muscle contraction by inhibiting myosin RLC phosphatase or by stimulating myosin RLC phosphorylation. We find that ROCK regulates airway smooth muscle contraction by activating the serine-threonine kinase Pak, which mediates the activation of Cdc42 and Neuronal-Wiskott-Aldrich Syndrome protein (N-WASp). N-WASP transmits signals from cdc42 to the Arp2/3 complex for the nucleation of actin filaments. These results demonstrate a novel molecular function for ROCK in the regulation of Pak and cdc42 activation that is critical for the processes of actin polymerization and contractility in airway smooth muscle. Rho kinase (ROCK), a RhoA GTPase effector, can regulate the contraction of airway and other smooth muscle tissues. In some tissues, ROCK can inhibit myosin regulatory light chain (RLC) phosphatase, which increases the phosphorylation of myosin RLC and promotes smooth muscle contraction. ROCK can also regulate cell motility and migration by affecting F-actin dynamics. Actin polymerization is stimulated by contractile agonists in airway smooth muscle tissues and is required for contractile tension development in addition to myosin RLC phosphorylation. We investigated the mechanisms by which ROCK regulates the contractility of tracheal smooth muscle tissues by expressing a kinase inactive mutant of ROCK, ROCK-K121G, in the tissues or by treating them with the ROCK inhibitor, H-1152P. Our results show no role for ROCK in the regulation of non-muscle or smooth muscle myosin RLC phosphorylation during contractile stimulation in this tissue

  3. 48 CFR 970.35 - Research and development contracting.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Research and development... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Major System Acquisition 970.35 Research and development contracting. ...

  4. Is contraction-stimulated glucose transport feedforward regulated by Ca2+?

    DEFF Research Database (Denmark)

    Jensen, Thomas Elbenhardt; Angin, Yeliz; Sylow, Lykke

    2014-01-01

    cell types. The literature is contrasted against our recent findings suggesting that SR Ca(2+) release is neither essential nor adequate to stimulate glucose transport in muscle. Instead, feedback signals through AMPK and mechanical stress are likely to account for most of contraction......In many cell types, Ca(2+) signals to increase the movement and surface membrane insertion of vesicles. In skeletal muscle, Ca(2+) is predominantly released from the sarcoplasmic reticulum (SR) to initiate contraction. Sarcoplasmic reticulum Ca(2+) release is widely believed to be a direct......-stimulated glucose transport. A revised working model is proposed, in which muscle glucose transport during contraction is not directly regulated by SR Ca(2+) release but rather responds exclusively to feedback signals activated secondary to cross-bridge cycling and tension development....

  5. 75 FR 51392 - Federal Management Regulation; Transportation Management

    Science.gov (United States)

    2010-08-20

    ...; Docket Number 2010-0011, sequence 1] RIN 3090-AJ03 Federal Management Regulation; Transportation Management AGENCY: Office of Governmentwide Policy, General Services Administration (GSA). ACTION: Final rule. SUMMARY: The General Services Administration (GSA) is amending the Federal Management Regulation (FMR) by...

  6. 77 FR 5750 - Office of Procurement and Property Management; Agriculture Acquisition Regulation, Labor Law...

    Science.gov (United States)

    2012-02-06

    ... Management; Agriculture Acquisition Regulation, Labor Law Violations; Withdrawal AGENCY: Office of... Agriculture Acquisition Regulation at subpart 422.70 entitled ``Labor Law Violations'' that would have a contractor certify upon accepting a contract that it is in compliance with all applicable labor laws and that...

  7. An Analysis of Internal Controls for DoD Contract Management

    Science.gov (United States)

    2015-12-01

    alternative control activities to reduce the risk of fraud ( COSO , 2013; GAO, 2014). Also, the Office of Management and Budget (OMB), which contains an...force. Since 1992, the Government Accountability Office (GAO) has identified contract management within the DOD as an area for high risk in fraud...force. Since 1992, the Government Accountability Office (GAO) has identified contract management within the DOD as an area for high risk in fraud

  8. Complexity, Contract Design and Incentive Design in the Construction Management Industry

    OpenAIRE

    Beg, Zeshawn Afsari

    2015-01-01

    In this paper I examine how one construction management company uses contract design and incentive design to respond to aspects of task complexity and relationship complexity present in its construction projects. In terms of contract design, I find that the company is unable to increase its use of cost-plus pricing when faced with technically complex projects. Instead, the company uses increased pre-execution design modification and price markups when technically complex projects are contract...

  9. Contracts and management services site support program plan WBS 6.10.14

    Energy Technology Data Exchange (ETDEWEB)

    Knoll, J.M. Jr.

    1994-09-01

    Contracts and Management Services is recognized as the central focal point for programs having company or sitewide application in pursuit of the Hanford Missions`s financial and operational objectives. Contracts and Management Services actively pursues cost savings and operational efficiencies through: Management Standards by ensuring all employees have an accessible, integrated system of clear, complete, accurate, timely, and useful management control policies and procedures; Contract Reform by restructuring the contract, organization, and cost accounting systems to refocus Hanford contract activities on output products; Systems and Operations Evaluation by directing the Cost Reduction program, Great Ideas, and Span of Management activities; Program Administration by enforcing conditions of Accountability (whether DEAR-based or FAR-based) for WHC, BCSR, ICF KH, and BHI; Contract Performance activities; chairing the WHC Cost Reduction Review Board; and analyzing companywide Performance Measures; Data Standards and Administration by establishing and directing the company data management program; giving direction to the major RL programs and mission areas for implementation of cost-effective and efficient data management practices; directing all operations, application, and interfaces contained within the Hanford PeopleCore System; directing accomplishment and delivery of TPA data management milestones; and directing the sitewide data management processes for Data Standards and the Data Directory.

  10. 48 CFR 1646.201 - Contract Quality Policy.

    Science.gov (United States)

    2010-10-01

    ... EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality... ensure that services acquired under the FEHB contract conform to the contract's quality and audit... assurance program required by the contract and will acknowledge in writing whether or not the system is...

  11. Psychological contracts and commitment amongst nurses and nurse managers: a discourse analysis.

    Science.gov (United States)

    McCabe, T J; Sambrook, Sally

    2013-07-01

    Few studies explore the link between the psychological contracts and the commitment of nursing professionals in the healthcare sector, and how perceived breaches of the psychological contract can impact on nurses' commitment levels. This study explores the connections between the psychological contracts and organisational and professional commitment of nurses and nurse managers. Semi-structured interviews were conducted with nurses and nurse managers, to explore the connections between their psychological contracts and organisational and professional commitment. Large acute and small community organisation within the British National Health Service. 28 nurses and 11 nurse managers working within an acute and a community sector organisation - 20 and 19 in each organisation. Participants were selected through a process of purposive sampling, reflecting variations in terms of age, grade, ward and tenure. A discourse analysis was conducted on the qualitative data from the thirty nine semi-structured interviews. Two overall themes emerged, professional and managerial values. Professional values included the sub-themes: professional recognition; immediate work environment - leadership and peer support; professional development and progression. Sub-themes under managerial values included: involvement; general management; resource management. The findings suggest that nurses and nurse managers are governed by relational psychological contracts, underpinned by an affective and to a lesser extent normative commitment towards the nursing profession. They emphasise 'professional values', and professional commitment, as the basis for positive psychological contracts amongst nursing professionals. There was anecdotal evidence of relational psychological contract breach, with decreasing job satisfaction as the outcome of perceived psychological contract breach. Positive psychological contracts and commitment levels amongst nursing professionals can be supported by managers been

  12. Performance Contracting as a Performance Management Tool in the Public Sector in Kenya: Lessons of learning

    Science.gov (United States)

    Hope, Kempe Ronald, Sr.

    2013-01-01

    The purpose of this article is to provide an assessment and analysis of public sector performance contracting as a performance management tool in Kenya. It aims to demonstrate that performance contracting remains a viable and important tool for improving public sector performance as a key element of the on-going public sector transformation…

  13. 25 CFR 533.3 - Submission of management contract for approval.

    Science.gov (United States)

    2010-04-01

    ...) For new contracts and new operations, a three (3)-year business plan which sets forth the parties... operations, a three (3)-year business plan which sets forth the parties' goals, objectives, budgets... 25 Indians 2 2010-04-01 2010-04-01 false Submission of management contract for approval. 533.3...

  14. A comparative analysis of quality management standards for contract research organisations in clinical trials.

    Science.gov (United States)

    Murray, Elizabeth; McAdam, Rodney

    2007-01-01

    This article compares and contrasts the main quality standards in the highly regulated pharmaceutical industry with specific focus on Good Clinical Practice (GCP), the standard for designing, conducting, recording and reporting clinical trials involving human participants. Comparison is made to ISO quality standards, which can be applied to all industries and types of organisation. The study is then narrowed to that of contract research organisations (CROs) involved in the conduct of clinical trials. The paper concludes that the ISO 9000 series of quality standards can act as a company-wide framework for quality management within such organisations by helping to direct quality efforts on a long-term basis without any loss of compliance. This study is valuable because comparative analysis in this domain is uncommon.

  15. 48 CFR 970.0407-1-3 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.0407... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Administrative Matters 970.0407-1-3 Contract clause. The contracting officer shall insert the clause at 970.5204-3, Access to and Ownership of Records...

  16. 48 CFR 970.0371-9 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.0371... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Improper Business Practices and Personal Conflicts of Interest 970.0371-9 Contract clause. The contracting officer shall insert the clause at 970...

  17. 48 CFR 970.1103-4 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.1103... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Describing Agency Needs 970.1103-4 Contract clause. Insert the clause at 48 CFR 52.211-5, Material Requirements, in solicitations and contracts. ...

  18. 48 CFR 970.0808-3 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.0808... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Required sources of supplies and services 970.0808-3 Contract clause. The contracting officer shall insert the clause at 970.5208-1, Printing, in all...

  19. 48 CFR 970.0370-2 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.0370... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Improper Business Practices and Personal Conflicts of Interest 970.0370-2 Contract clause. (a) The contracting officer shall insert the clause at 970...

  20. 48 CFR 970.1170-2 - Contract provision.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract provision. 970... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Describing Agency Needs 970.1170-2 Contract provision. The Contracting Officer shall insert the clause at 970.5211-1, Work authorization, in each...

  1. Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction.

    Science.gov (United States)

    Kanai, Stanley M; Edwards, Alethia J; Rurik, Joel G; Osei-Owusu, Patrick; Blumer, Kendall J

    2017-11-24

    Regulator of G protein signaling 2 (RGS2) controls signaling by receptors coupled to the G q/11 class heterotrimeric G proteins. RGS2 deficiency causes several phenotypes in mice and occurs in several diseases, including hypertension in which a proteolytically unstable RGS2 mutant has been reported. However, the mechanisms and functions of RGS2 proteolysis remain poorly understood. Here we addressed these questions by identifying degradation signals in RGS2, and studying dynamic regulation of G q/11 -evoked Ca 2+ signaling and vascular contraction. We identified a novel bipartite degradation signal in the N-terminal domain of RGS2. Mutations disrupting this signal blunted proteolytic degradation downstream of E3 ubiquitin ligase binding to RGS2. Analysis of RGS2 mutants proteolyzed at various rates and the effects of proteasome inhibition indicated that proteolytic degradation controls agonist efficacy by setting RGS2 protein expression levels, and affecting the rate at which cells regain agonist responsiveness as synthesis of RGS2 stops. Analyzing contraction of mesenteric resistance arteries supported the biological relevance of this mechanism. Because RGS2 mRNA expression often is strikingly and transiently up-regulated and then down-regulated upon cell stimulation, our findings indicate that proteolytic degradation tightly couples RGS2 transcription, protein levels, and function. Together these mechanisms provide tight temporal control of G q/11 -coupled receptor signaling in the cardiovascular, immune, and nervous systems. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  2. Assessing Contract Management Maturity: U.S. Army Joint Munitions and Lethality Contracting Center, Army Contracting Command, Picatinny Arsenal

    Science.gov (United States)

    2009-09-01

    demonstrate competence” ( Jones , 2006). Most organizations conduct performance management for their employees with actions such as, setting goals...take the 14 form of comprehensive questionnaires, SWOT analyses or diagnostic models and include a comparison of results to various best practices...procnet.pica.army.mil/ Jones , R. (2006). CIDA Organizational Assessment Guide. Retrieved on March 1, 2009 from: http://www.acdi-cida.gc.ca/CIDAWEB

  3. 48 CFR 970.3770 - Facilities management.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Facilities management. 970... REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Facilities Management Contracting 970.3770 Facilities management. ...

  4. 25 CFR 900.118 - Do these “construction contract” regulations apply to construction management services?

    Science.gov (United States)

    2010-04-01

    ... construction management services? 900.118 Section 900.118 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE...” regulations apply to construction management services? No. Construction management services may be contracted separately under section 108 of the Act. Construction management services consultants and/or Indian tribe or...

  5. Behavioural changes experienced by contract managers while working on remote project sites

    OpenAIRE

    2012-01-01

    M.B.A. This research project is concerned with the behavioural changes of contract managers while working on 'remote' project sites. While working on such a project, the researcher became aware that the behaviour of certain contract managers changed over the course of the project, and that this behaviour was not the same as they demonstrated when at home or in the office environment. In many instances these behavioural changes were of a negative nature, the consequences of which often resu...

  6. Customer relationship management in the contract pharmaceutical industry: an exploratory study for measuring success.

    Science.gov (United States)

    Kros, John F; Nadler, Scott; Molis, Justin

    2007-01-01

    Managing customer relationships is a very important issue in business-to-business markets. This research investigates the growing number of available resources defining Customer Relationship Management (CRM) efforts, and how they are being applied within the Contract Pharmaceutical Manufacturing industry. Exploratory study results using face-to-face and telephone questionnaires based on four criteria for rating a company's CRM efforts are presented. Data was collected from large Contract Pharmaceutical Manufacturing companies in the US market. The results and conclusions are discussed relating how the Contract Pharmaceutical Manufacturing industry is implementing CRM including some potential steps to take when considering a CRM initiative.

  7. Vascular Function and Regulation of Blood Flow in Resting and Contracting Skeletal Muscle

    DEFF Research Database (Denmark)

    Nyberg, Michael Permin

    importance. The present work provides new insight in to vasodilator interactions important for exercise hyperemia and sheds light on mechanisms important for vascular function and regulation of skeletal muscle blood flow in essential hypertension (high blood pressure) and aging and identifies mechanisms......The precise matching of blood flow, oxygen delivery and metabolism is essential as it ensures that any increase in muscle work is precisely matched by increases in oxygen delivery. Therefore, understanding the control mechanisms of skeletal muscle blood flow regulation is of great biological...... in the regulation of exercise hyperemia. Furthermore, blood flow to contracting leg skeletal muscles is reduced both in essential hypertension and with aging. The potential difference in vasoactive system(s) responsible for the reduction in blood flow in the two conditions is in agreement with the suggestion...

  8. Defense Procurement: An Analysis of Contract Management Internal Controls

    Science.gov (United States)

    2015-03-22

    management to discuss what could go wrong within the organization and how to best mitigate any potential risks , including fraud risks ( COSO , 2013...knowledge management system supporting its governance of processes and practices (Power, 1996, p. 289). Organizations’ increased concern for risk ...meeting the organizational goals set by management ( COSO , 2013). If any controls need to be updated, changed, removed, or added, management can

  9. Contracting for Public Services

    DEFF Research Database (Denmark)

    Greve, Carsten

    strategic purchasing understanding markets communicating the contracting decision designing and drafting the contract the role of the consumer the regulation of service provision Illustrated throughout with practitioner case-studies from a range of OECD countries, this book presents an important new......Insightful and comprehensive and covering new subjects like globalization and IT, this text, international in its approach, provides a thorough introduction to the key phases of the contracting process and the skills required by managers in its implementation. These include: policy for contracting...

  10. French regulations and waste management

    International Nuclear Information System (INIS)

    Sousselier, Y.

    1985-01-01

    The authors describe the organization and the role of safety authorities in France in matter of waste management. They precise the French policy in waste storage and treatment: basic objectives, optimization of waste management. The safety requirements are based upon the barrier principle. Safety requirements about waste conditioning and waste disposal are mentioned. In addition to the safety analysis and studies described above, the Protection and Nuclear Safety Institute assists the ministerial authorities in the drafting of ''basic safety rules (RFS)'', laying down safety objectives. Appendix 1 and Appendix 2 deal with safety aspects in spent fuel storage and in transportation of radioactive materials [fr

  11. French regulation and waste management

    International Nuclear Information System (INIS)

    1984-08-01

    The organization and the role played by French safety authorities for waste management are described. The French policy for storage and conditioning: basic objectives and waste management optimization are specified. Safety requirements are based on the barrier principle, they are mentioned for packaging and storage. The ''Institut de Protection et Surete Nucleaire'' deals not only with safety analysis but also help the ''autorites ministerielles'' for the development of fundamental safety rules. Examples for spent fuel storage and radioactive materials transport are treated in appendixes [fr

  12. 48 CFR 1851.205 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract clause. 1851.205 Section 1851.205 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACT MANAGEMENT USE OF GOVERNMENT SOURCES BY CONTRACTORS Contractor Use of Interagency Fleet Management...

  13. Regulation on radioactive waste management

    International Nuclear Information System (INIS)

    1999-01-01

    A national calculator control system for the metropolitan radioactive waste banks was developed in 1999. The NNSA reviewed by the regulations the feasibility of some rectification projects for uranium ore decommissioning and conducted field inspections on waste treating systems and radioactive waste banks at the 821 plant. The NNSA realized in 1999 the calculator control for the disposal sites of low and medium radioactive waste. 3 routine inspections were organized on the reinforced concrete structures for disposal units and their pouring of concrete at waste disposal site and specific requirements were put forth

  14. Recent trends in selenium regulation and management

    International Nuclear Information System (INIS)

    Sobolewski, A.

    2010-01-01

    Selenium is a contaminant encountered at uranium mines. When discharged into water, it can build up in the food chain and become toxic to egg-laying fish and shorebirds. This presentation reviews recent developments in its regulation, management and treatment. Selenium will soon be regulated on the basis of its concentration in fish or bird eggs, not its dissolved concentrations, which challenges managers trying to establish acceptable discharge limits. Information supporting this change will be discussed. Recent developments to manage and treat selenium will also be reviewed, emphasizing new chemical and biological treatment processes applicable at uranium mines and mill sites. (author)

  15. Gas contract portfolio management: a stochastic programming approach

    International Nuclear Information System (INIS)

    Haurie, A.; Smeers, Y.; Zaccour, G.

    1991-01-01

    This paper deals with a stochastic programming model which complements long range market simulation models generating scenarios concerning the evolution of demand and prices for gas in different market segments. Agas company has to negociate contracts with lengths going from one to twenty years. This stochastic model is designed to assess the risk associated with committing the gas production capacity of the company to these market segments. Different approaches are presented to overcome the difficulties associated with the very large size of the resulting optimization problem

  16. Cutting out the middleman: physicians can contract directly with employers--a viable alternative to adversarial managed care agreements.

    Science.gov (United States)

    Lester, Howard

    2002-01-01

    HMOs, PPOs, and other managed care "middlemen" control the means by which most physicians do business with employers. As physicians face dwindling reimbursements, greater practice restrictions, and increased pressure to sign adversarial middleman contracts, interest in direct contracting has grown. This article introduces direct contracting as an important alternative to commercial managed care agreements; cites the key advantages and process of direct contracting; and offers practical recommendations for helping physician practices successfully negotiate direct physician/employer agreements.

  17. Facilitating major additions to gas pipeline capacity: innovative approaches to financing, contracting, and regulation

    International Nuclear Information System (INIS)

    Schlesinger, B.; George, R.

    1997-01-01

    The North American gas pipeline industry is in the process of changing from a highly regulated merchant business to a less-regulated, more competitive, transportation industry. This has changed the risk profiles of many companies. This study examined various innovative approaches to successfully financing major pipeline projects emphasizing pipeline capacity financing, contractual terms between shippers and pipelines, and regulatory developments. Besides suggesting options to enhance prospects for financing major pipeline expansion projects, the study also aimed at creating a better understanding of the regulatory market and commercial changes in the pipeline industry and their financing implications. The study also includes a review of the evolution in gas markets and a record of consultations with lenders, producers, marketers and users. Innovative financing, contracting and regulatory solutions are identified and assessed. 25 refs., 17 tabs., 16 figs

  18. The economical contracting management in Agricultural Cooperatives: tools for evaluating their performance.

    Directory of Open Access Journals (Sweden)

    Rafael Enrique Viña Echevarría

    2014-06-01

    Full Text Available The economic and management contracts involve strategic actions, legal and operational purposes that make possible to convert the goal of an organization on results that express the fulfillment of the mandates and satisfies customers on the basis of the duties and obligations set out in the negotiating document. This article aims to get inside into the performance evaluation of the management of the recruitment of Agricultural Cooperatives and to reflex about the insufficiencies evidenced in this process. To which we developed a theoretical valuation and economic procurement praxiological showing a group of deficiencies that have impacted in the contracts management The study was able to obtain, process, analyze, interpret and argue the problems associated with economic contracting and justify the need to propose a system of indicators to assess recruitment management Agricultural Cooperatives in the province of Sancti Spiritus, the results revealed the ineffectiveness of the process and the negative impact on the productive base.

  19. Sustainable Regulation of Information Sharing with Electronic Data Interchange by a Trust-Embedded Contract

    Directory of Open Access Journals (Sweden)

    Guanghua Han

    2017-06-01

    Full Text Available This paper studies the risks in demand information sharing applications by electronic soft-orders using electronic data interchange (EDI systems in e-commerce and aims to suggest a sustainable regulation mechanism with a trust-embedded contract. In a supply chain with one retailer and one supplier, the retailer solicits private forecasted demand and places soft-orders via EDI to the supplier. To ensure abundant supply, the retailer has an incentive to inflate her soft-orders, which potentially harms the credible information sharing and sustainability of business cooperation. Normally, the degree to which the supplier relies on the retailer’s order information is specified by trust, which is evaluated according to the retailer’s reputation and supplier’s intuition in this study. Based on standard game theory, we find that both the retailer’s order and the quantity of supplier prepared materials are independent of the retailer’s forecast. Therefore, EDI based information sharing in e-commerce without a regulation mechanism leads to inefficient demand information sharing. Since both the supplier and retailer are proved to faces huge of potential profit losses due to the failure of information sharing, the commerce by EDI based information sharing is full of risk and unsustainable. Therefore, a regulation mechanism that leaded by the retailer is proposed to establish ‘win-win’ sustainable cooperation. Numerical experiments highlight the value of trust, the impact of reputation and intuition in decisions, and the effectiveness of the regulation mechanism by a cost-sharing contract.

  20. Exploration and practice on contract management of Daya Bay Nuclear Power Station

    International Nuclear Information System (INIS)

    Wang Yonggang

    2002-01-01

    In the market economy, Daya Bay Nuclear Power Station needs to out source or allow to suppliers among industries, while concentrating its core competitive capability, for safely and stable operation. By evaluating the features of contract management in Daya Bay Nuclear Power Station, set up the organization and process of the supply management

  1. Implementation guide for Hanford Tanks Initiative C-106 heel retrieval contract management HNF-2511

    International Nuclear Information System (INIS)

    McDaniel, L.B.

    1998-01-01

    This report is an Implementation Guide for Hanford Tanks Initiative C-106 heel retrieval contract management HNF-2511 to provide a set of uniform instructions for managing the two contractors selected. The primary objective is to produce the necessary deliverables and services for the HTI project within schedule and budget

  2. Optimal contract for a fund manager, with capital injections and endogenous trading constraints

    OpenAIRE

    Nadtochiy, Sergey; Zariphopoulou, Thaleia

    2018-01-01

    In this paper, we construct a solution to the optimal contract problem for delegated portfolio management of the fist-best (risk-sharing) type. The novelty of our result is (i) in the robustness of the optimal contract with respect to perturbations of the wealth process (interpreted as capital injections), and (ii) in the more general form of principals objective function, which is allowed to depend directly on the agents strategy, as opposed to being a function of the generated wealth only. ...

  3. Defense Contract Management Command Capitalization of Fixed Assets

    National Research Council Canada - National Science Library

    Young, Shelton

    1997-01-01

    The audit objective was to determine whether the Defense Logistics Agency and the Defense Finance and Accounting Service had implemented effective management control procedures and complied with laws...

  4. Unaccustomed eccentric contractions impair plasma K+ regulation in the absence of changes in muscle Na+,K+-ATPase content.

    Directory of Open Access Journals (Sweden)

    Craig A Goodman

    Full Text Available The Na+,K+-ATPase (NKA plays a fundamental role in the regulation of skeletal muscle membrane Na+ and K+ gradients, excitability and fatigue during repeated intense contractions. Many studies have investigated the effects of acute concentric exercise on K+ regulation and skeletal muscle NKA, but almost nothing is known about the effects of repeated eccentric contractions. We therefore investigated the effects of unaccustomed maximal eccentric knee extensor contractions on K+ regulation during exercise, peak knee extensor muscle torque, and vastus lateralis muscle NKA content and 3-O-MFPase activity. Torque measurements, muscle biopsies, and venous blood samples were taken before, during and up to 7 days following the contractions in six healthy adults. Eccentric contractions reduced peak isometric muscle torque immediately post-exercise by 26±11% and serum creatine kinase concentration peaked 24 h post-exercise at 339±90 IU/L. During eccentric contractions, plasma [K+] rose during Set 1 and remained elevated at ∼4.9 mM during sets 4-10; this was despite a decline in work output by Set 4, which fell by 18.9% at set 10. The rise in plasma [K+] x work(-1 ratio was elevated over Set 2 from Set 4- Set 10. Eccentric contractions had no effect on muscle NKA content or maximal in-vitro 3-O-MFPase activity immediately post- or up to 7 d post-exercise. The sustained elevation in plasma [K+] despite a decrease in work performed by the knee extensor muscles suggests an impairment in K+ regulation during maximal eccentric contractions, possibly due to increased plasma membrane permeability or to excitation-contraction uncoupling.

  5. 77 FR 5714 - Office of Procurement and Property Management; Agriculture Acquisition Regulation, Labor Law...

    Science.gov (United States)

    2012-02-06

    ... Management; Agriculture Acquisition Regulation, Labor Law Violations; Withdrawal AGENCY: Office of... 422.70 entitled ``Labor Law Violations'' that would have a contractor certify upon accepting a contract that it is in compliance with all applicable labor laws and that, to the best of its knowledge...

  6. Privacy Management Contracts And Economics, Using Service Level Agreements (Sla)

    NARCIS (Netherlands)

    L-F. Pau (Louis-François)

    2005-01-01

    textabstractRecognizing the importance of privacy management as a business process and a business support process, this paper proposes the use of service level agreements around privacy features, including qualitative and quantitative ones. It also casts privacy management into a business

  7. Management in general practice: the challenge of the new General Medical Services contract.

    Science.gov (United States)

    Checkland, Kath

    2004-10-01

    Managers in general practice perform a variety of roles, from purely administrative to higher-level strategic planning. There has been little research investigating in detail how they perform these roles and the problems that they encounter. The new General Medical Services (GMS) contract contains new management challenges and it is not clear how practices will meet these. To improve understanding of the roles performed by managers in general practice and to consider the implications of this for the implementation of the new GMS contract. In-depth qualitative case studies covering the period before and immediately after the vote in favour of the new GMS contract. Three general practices in England, chosen using purposeful sampling. Semi-structured interviews with all clinical and managerial personnel in each practice, participant and non-participant observation, and examination of documents. Understanding about what constitutes the legitimate role of managers in general practice varies both within and between practices. Those practices in the study that employed a manager to work at a strategic level with input into the direction of the organisation demonstrated significant problems with this in practice. These included lack of clarity about what the legitimate role of the manager involved, problems relating to the authority of managers in the context of a partnership, and lack of time available to them to do higher-level work. In addition, general practitioners (GPs) were not confident about their ability to manage their managers' performance. The new GMS contract will place significant demands on practice management. These results suggest that it cannot be assumed that simply employing a manager with high-level skills will enable these demands to be met; there must first be clarity about what the manager should be doing, and attention must be directed at questions about the legitimacy enjoyed by such a manager, the limits of his or her authority, and the

  8. Memories of early work on muscle contraction and regulation in the 1950's and 1960's

    International Nuclear Information System (INIS)

    Huxley, Hugh E.

    2008-01-01

    Professor Ebashi's epic work on the biochemistry of the regulation of muscle contraction began in the early 1950's, during the same period that work on the molecular basis of force production in muscle was also beginning. The latter work started in two MRC Research Units in the UK, and was continued jointly by the two workers from those Units who had, independently, gone to MIT to learn the new techniques of electron microscopy and to apply them to muscle. In a somewhat similar fashion, Professor Ebashi also spent one or two years in the USA, continuing his work on the role of calcium in muscle regulation in Lippman's laboratory, before returning to Japan to achieve the great breakthroughs in this work during the 1960's. Hanson and Huxley, after putting forward the overlapping actin and myosin filament arrays model for the striated muscle sarcomere, and subsequently the sliding filament model of muscle contraction (simultaneously with A.F Huxley and R. Niedergerke), returned to the UK to pursue detailed structural studies in separate Research Units, in a mixture of consultation, collaboration, and competition, during the later 1950's and throughout the 1960's. However, the path to enlightenment described here in some detail was somewhat more tortuous than the standard literature perhaps reveals. Nevertheless, by the time of the Cold Spring Harbor Symposium on Muscle Contraction in 1972, the two lines of enquiry on regulation itself, and on the tilting cross-bridge model of force production, had arrived at a good deal of common ground, and indeed the identification of troponin and its periodic distribution along the actin filaments had helped resolve a long-standing puzzle in the interpretation of the low angle X-ray diagram. Since then, an enormous amount of remarkable new work has been necessary to establish troponin regulation and the tilting cross-bridge mechanism in molecular detail, but the work in the 1950's and 1960's has provided a firm and accurate basis

  9. The Evolving Contingency Contracting Market: Private Sector Self regulation and United States Government Monitoring of Procurement of Stability Operations Services

    Science.gov (United States)

    2016-01-01

    statements of work would be useful in ensuring ethical govern- ment procurement practices. Conclusions The United States conducts diplomatic, defense...THE EVOLVING CONTINGENCY CONTRACTING MARKET: PRIVATE SECTOR SELF-REGULATION AND UNITED STATES GOVERNMENT MONITORING OF PROCUREMENT OF STABILITY...MARKET: PRIVATE SECTOR SELF-REGULATION AND UNITED STATES GOVERNMENT MONITORING OF PROCUREMENT OF STABILITY OPERATIONS SERVICES Whitney Grespin January

  10. 25 CFR 900.114 - Why is there a separate subpart in these regulations for construction contracts and grants?

    Science.gov (United States)

    2010-04-01

    ... SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Construction § 900.114 Why is there a separate subpart in these regulations for construction contracts and grants? There is a separate subpart because the... 25 Indians 2 2010-04-01 2010-04-01 false Why is there a separate subpart in these regulations for...

  11. WasteWise Resource Management: Innovative Solid Waste Contracting Methods

    Science.gov (United States)

    Resource management is an innovative contractual partnership between a waste-generating organization and a qualified contractor that changes the nature of current disposal services to support waste minimization and recycling.

  12. SEVERAL OBSERVATIONS REGARDING THE REGULATION OF THE CONTRACT OF PARTNERSHIP IN THE NEW CIVIL CODE

    Directory of Open Access Journals (Sweden)

    IOLANDA-ELENA CADARIU-LUNGU

    2012-05-01

    Full Text Available Following the model of the Italian Civil Code, of the Civil Code from Quebec, the Swiss and the Dutch ones, the new Romanian Civil Code has adopted the monist conception of regulating the private law relationships, gathering in the same normative act traditional civil law dispositions as well as dispositions that are specific to the commercial relationships among professionals. In this regulating context, one of the fundamental changes the new Civil Code brings is the unification of the legal regime applicable to civil and commercial contracts, with all the consequences that derive from this new legislative approach. This fundamental modification is first determined by the profound change of the character of social, economic and juridical relationships, by the change of the cultural level of the Romanian society, by the closeness of the two branches of civil and commercial law and, last but not least, by the evolution of the business environment. In this line of thought, we can identify important changes in the matter of the contract of partnership which, as regulated by the new Civil Code, constitutes the common law both for the simple partnerships (former civil societies as well as for the commercial companies, to which the special legislation still in force in the matter still applies. In this study we aimed at analyzing the general common features of all associative forms listed by art. 1.888 Civil Code and the new elements in the matter, with critical observations where needed, which take the form of a comparison with the specific legislation in the field from the Civil Codes that served as a source of inspiration for the Romanian legislator.

  13. Risk Taking and Optimal Contracts for Money Managers

    OpenAIRE

    Palomino, Frédéric; Prat, Andrea

    1999-01-01

    Recent empirical work suggests a strong connection between the incentives money managers are offered and their risk-taking behavior. We develop a general model of delegated portfolio management, with the feature that the agent can control the riskiness of the portfolio. This represents a departure from the existing literature on agency theory in that moral hazard is not only effort exertion but also risk taking behavior. The moral hazard problem with risk taking involves an incentive-compatib...

  14. [The use of management contracts and professional incentives in the public health sector].

    Science.gov (United States)

    Ditterich, Rafael Gomes; Moysés, Simone Tetu; Moysés, Samuel Jorge

    2012-04-01

    Results-based management is a cornerstone of reform in public administration, including the health field, and has become the basis for other innovations such as the institutionalization of management contracts and the use of professional incentives. This review article aims to introduce and discuss the use of such management contracts in the public health sector. Management by results has developed means and tools that highlight the importance of shared responsibility and mutual commitment between workers and management-level directors. Thus, preset goals are negotiated among all the stakeholders and are evaluated periodically in order to grant professional incentives. It is necessary to improve the mechanisms for control and observation, to more precisely determine the healthcare and management indicators and their patterns, to train stakeholders in designing the plan, and to improve the use of professional incentives in order to effectively increase accountability vis-à-vis the desired results.

  15. Dependence on Supplier, Supplier Trust and Green Supplier Integration: The Moderating Role of Contract Management Difficulty

    Directory of Open Access Journals (Sweden)

    Xuesong Zhao

    2018-05-01

    Full Text Available This study aims to investigate the impacts of dependence on supplier and supplier trust on green supplier integration, and the moderating role of contract management difficulty. In this study, we develop a dependence-trust-integration model based on resource dependence theory, social capital theory and transaction cost theory. We examine the hypothesized relationships using hierarchical regression analyses based on data collected from 187 Chinese firms. Our findings suggest that dependence on supplier has positive impacts on green supplier integration and supplier trust. Supplier trust partially mediates the relationship between dependence on supplier and green supplier integration. In addition, contract management difficulty negatively moderates the relationship between supplier trust and green supplier integration. This research contributes to the literature by offering empirical evidence concerning the indirect relationship between dependence on supplier and green supplier integration via supplier trust, and the trust-integration link depends on the level of contract management difficulty.

  16. 48 CFR 244.403 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract clause. 244.403... OF DEFENSE CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND PROCEDURES Subcontracts for Commercial Items and Commercial Components 244.403 Contract clause. (1) 252.225-7009, Restriction on Acquisition of...

  17. Reduction of construction wastes by improving construction contract management: a multinational evaluation.

    Science.gov (United States)

    Mendis, Daylath; Hewage, Kasun N; Wrzesniewski, Joanna

    2013-10-01

    The Canadian construction industry generates 30% of the total municipal solid waste deposited in landfills. Ample evidence can be found in the published literature about rework and waste generation due to ambiguity and errors in contract documents. Also, the literature quotes that disclaimer clauses in contract documents are included in the contractual agreements to prevent contractor claims, which often cause rework. Our professional practice has also noted that there are several disclaimer clauses in standard contract documents which have the potential to cause rework (and associated waste). This article illustrates a comparative study of standard contractual documents and their potential to create rework (and associated waste) in different regions of the world. The objectives of this study are (1) to analyse standard contractual documents in Canada, the USA and Australia in terms of their potential to generate rework and waste, and (2) to propose changes/amendments to the existing standard contract documents to minimise/avoid rework. In terms of construction waste management, all the reviewed standard contract documents have deficiencies. The parties that produce the contract documents include exculpatory clauses to avoid the other party's claims. This approach tends to result in rework and construction waste. The contractual agreements/contract documents should be free from errors, deficiencies, ambiguity and unfair risk transfers to minimise/avoid potential to generate rework and waste.

  18. 75 FR 2463 - Continuing Contract for Civil Works Project Managed by the United States Army Corps of Engineers...

    Science.gov (United States)

    2010-01-15

    ... be considered a breach of contract and shall not entitle the Contractor to a price adjustment under... constitute a breach of this contract and shall not entitle the Contractor to any price adjustment under the... Continuing Contract for Civil Works Project Managed by the United States Army Corps of Engineers Clauses...

  19. Shadow management applied in the first AP1000 project under the islands contract condition

    International Nuclear Information System (INIS)

    Liu Xiao

    2010-01-01

    As the global first AP1000 nuclear project, Sanmen phase I nuclear project itself has many challenges from design, procurement to construction managements for non practical nuclear project and experience can be referenced. Islands contract pattern was adopted by this project and this contract pattern has its own strength and weakness. Considering the negative influence result from the first unit, this project has the great postpone risk. Shadow management here tries to reduce these risks and enhance the project surveillance and control by the owner to promote the final goal of this project. (authors)

  20. Project brief of pre-contract in project management

    International Nuclear Information System (INIS)

    Mohd Jamil Hashim; Mohd Azmi Sidid Omar; Abdul Rahman Norazumin; Zakaria Dris; Abdul Murad Abu Bakar; Alwi Othman

    2010-01-01

    Project brief is a comprehensive document used in translating the user needs and requirement for the project implementation. This document is important for the designer as a main guidance towards establishing project details. Research shown that problem usually arises from not well-defined scope and needs by the user. With lack of information the designer tend to assume and interprets wrong translation. Other issues arise from project management are time, cost, budgetary, lack of communication and establishing quality management. Some ideas of improvement were gain by doing cross reference with JKR quality system management, workshop and brainstorming. It shows that an improvement of data collection system has to be integrating with some basic format details, drawings and declaration forms to be established. (author)

  1. 48 CFR 46.202-1 - Contracts for commercial items.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contracts for commercial... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 46.202-1 Contracts for commercial items. When acquiring commercial items (see part 12), the Government shall rely on contractors' existing...

  2. 48 CFR 46.305 - Cost-reimbursement service contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cost-reimbursement service... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.305 Cost-reimbursement service contracts. The contracting officer shall insert the clause at 52.246-5, Inspection of Services—Cost Reimbursement, in...

  3. 48 CFR 46.303 - Cost-reimbursement supply contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cost-reimbursement supply... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.303 Cost-reimbursement supply contracts. The contracting officer shall insert the clause at 52.246-3, Inspection of Supplies—Cost-Reimbursement, in...

  4. Final Report on the Audit of the Administration of the Contract Closeout Process at the Defense Contract Management Region, Dallas

    National Research Council Canada - National Science Library

    1990-01-01

    .... The audit was made from January to October 1989. The objectives of the audit were to determine the timeliness of the contract closeout process, the validity of unliquidated obligations on contracts awaiting closeout, and the timeliness...

  5. School Building Projects: Managing Insurance and Contracts during Construction

    Science.gov (United States)

    Shands, Richard

    2011-01-01

    Managing the risks inherent in a building project presents a challenge and opportunities not often encountered in the ordinary affairs of a school district. A building project brings the district, its staff, and students, as well as the community, in close contact with architects and engineers and a number of contractors for a period of time often…

  6. Beyond the contract: managing risk in supply chain relations

    NARCIS (Netherlands)

    Dekker, H.C.; Sakaguchi, J.; Kawai, T.

    2013-01-01

    As a consequence of the development of intensified relations with suppliers, for many firms the supply chain has become a significant source of risk exposure. In this paper we examine firms' use of control practices to manage risks associated with intensified collaboration with supply chain

  7. Interleukin-6 receptor expression in contracting human skeletal muscle: regulating role of IL-6

    DEFF Research Database (Denmark)

    Keller, Pernille; Penkowa, Milena; Keller, Charlotte

    2005-01-01

    Contracting muscle fibers produce and release IL-6, and plasma levels of this cytokine are markedly elevated in response to physical exercise. We recently showed autocrine regulation of IL-6 in human skeletal muscle in vivo and hypothesized that this may involve up-regulation of the IL-6 receptor....... Infusion of rhIL-6 to humans had no effect on the mRNA level of the IL-6 receptor, whereas there was an increase at the protein level. IL-6 receptor mRNA increased similarly in muscle of both IL-6 KO mice and wild-type mice in response to exercise. In conclusion, exercise increases IL-6 receptor production....... Therefore, we investigated IL-6 receptor regulation in response to exercise and IL-6 infusion in humans. Furthermore, using IL-6-deficient mice, we investigated the role of IL-6 in the IL-6 receptor response to exercise. Human skeletal muscle biopsies were obtained in relation to: 3 h of bicycle exercise...

  8. Governance of nanotechnology and nanomaterials: principles, regulation, and renegotiating the social contract.

    Science.gov (United States)

    Kimbrell, George A

    2009-01-01

    Good governance for nanotechnology and nanomaterials is predicated on principles of general good governance. This paper discusses on what lessons we can learn from the oversight of past emerging technologies in formulating these principles. Nanotechnology provides us a valuable opportunity to apply these lessons and a duty to avoid repeating past mistakes. To do that will require mandatory regulation, grounded in precaution, that takes into account the uniqueness of nanomaterials. Moreover, this policy dialogue is not taking place in a vacuum. In applying the lessons of the past, nanotechnology provides a window to renegotiate our public's social contract on chemicals, health, the environment, and risks. Emerging technologies illuminate structural weaknesses, providing a crucial chance to ameliorate lingering regulatory inadequacies and provide much needed updates of existing laws.

  9. Further Improvements Needed in Navy’s Oversight and Management of Contracting for Facilities Construction on Diego Garcia.

    Science.gov (United States)

    1984-05-23

    1981, the Navy awarded a cost reimbursable contract to a joint venture to construct facility projects for fiscal years 1981 and 1982 with an estimated...through fiscal year 1986. In July 1981, the Navy awarded a cost reimburs - able contract (cost plus award fee) to Raymond, Brown & Root, Molem, a joint...Navy’s oversight and management of the acquisition of these facilities. A COST REIMBURSABLE CONTRACT MAKES STRONG CONTRACT ADMINISTRATION VITAL Under

  10. Using Blockchain and smart contracts for secure data provenance management

    OpenAIRE

    Ramachandran, Aravind; Kantarcioglu, Dr. Murat

    2017-01-01

    Blockchain technology has evolved from being an immutable ledger of transactions for cryptocurrencies to a programmable interactive the environment for building distributed reliable applications. Although, blockchain technology has been used to address various challenges, to our knowledge none of the previous work focused on using blockchain to develop a secure and immutable scientific data provenance management framework that automatically verifies the provenance records. In this work, we le...

  11. Usage of Option Contracts for Foreign Exchange Risk Management

    Directory of Open Access Journals (Sweden)

    Daniel Armeanu

    2007-06-01

    Full Text Available Today in Romania, in the context of the liberalization of the capital account and under a floating exchange rate (official is a managed floating currency regime established by National Bank of Romania the foreign exchange rate is very volatile. In consequence the financial institutions, corporations and, especially, the importers and exporters have to deal with a big exposition of currency risk related with their activities. Financial institutions and corporations today must adopt new roles in order to compete successfully in the explosively evolving foreign exchange markets. The methods, instruments and techniques used to manage foreign exchange risk are more complex than ever before. The objective of our paper is to provide the techniques and insights needed to pinpoint opportunities and control risks. We will present the most modern practical methods for managing the currency risk: option strategies (spread, strangle, straddle, etc. Also we will present the advantage, the disadvantage and our opinions related with the use of currency derivatives instruments (especially currency strategies options, making a comparative analysis.

  12. The new Facilities Management contract at CERN from 1st July 2002

    CERN Document Server

    Mauro Nonis

    2002-01-01

    Within the ST Division, all the Facilities Management activities have been under the ST/TFM group responsibility until the 30th June 2002, who has performed them using around 20 industrial support contracts. Starting from the 1st July 2002 a new unit, ST/FM, will take over these activities that will be unified into one single contract that has been adjudicated to the company Facilities Management Network SA. This contract will be in charge of the maintenance and minor works on tertiary installations (i.e. all structures and installations that have no direct relation to the running of the accelerators) for the following trades: - Technical: heating, ventilation, air conditioning, plumbing, electricity, civil engineering (painting, roofing, glazing, blinds, fencing, masonry etc.), passenger and goods lifts, automatic and powered doors, kitchen equipment, roads, signs, keys and locks, office furniture, - Services: waste collection, security, green areas, cleaning and sanitary supplies, disinfection, rodent cont...

  13. THE NEW FACILITIES MANAGEMENT CONTRACT AT CERN FROM 1st JULY 2002

    CERN Multimedia

    Mauro Nonis

    2002-01-01

    Within the ST Division, all the Facilities Management activities have been under the ST/TFM group responsibility until the 30th June 2002, who has performed them using around 20 industrial support contracts. Starting from the 1st July 2002 a new unit, ST/FM, will take over these activities that will be unified into one single contract that has been adjudicated to the company Facilities Management Network SA. This contract will be in charge of the maintenance and minor works on tertiary installations (i.e. all structures and installations that have no direct relation to the running of the accelerators) for the following trades: Technical: heating, ventilation, air conditioning, plumbing, electricity, civil engineering (painting, roofing, glazing, blinds, fencing, masonry etc.), passenger and goods lifts, automatic and powered doors, kitchen equipment, roads, signs, keys and locks, office furniture, Services: waste collection, security, green areas, cleaning and sanitary supplies, disinfection, rodent contro...

  14. Super Energy Savings Performance Contracts: Federal Energy Management Program (FEMP) Program Overview (revision)

    International Nuclear Information System (INIS)

    Pitchford, P.

    2001-01-01

    This four-page publication describes the U.S. Department of Energy's (DOE's) streamlined energy savings performance contracting, or ''Super ESPC,'' process, which is managed by DOE's Federal Energy Management Program (FEMP). Under a Super ESPC, a qualifying energy service company (ESCO) from the private sector pays for energy efficiency improvements or advanced renewable energy technologies (e.g., photovoltaic systems, wind turbines, or geothermal heat pumps, among others) for a facility of a government agency. The ESCO is then repaid over time from the agency's resulting energy cost savings. Delivery orders under these contracts specify the level of performance (energy savings) and the repayment schedule; the contract term can be up to 25 years, although many Super ESPCs are for about 10 years or less

  15. Regulation, control, tele-management; Regulation, commande, telegestion

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    In 1998, the French public authorities have started an ambitious energy mastery policy under the auspices of the Agency of environment and energy mastery (Ademe). One aspect of this policy concerns the R and D, industrial development and applications of automation and computerized control to the energy systems of buildings. This RCT 2000 seminar takes stock of the recent advances in this domain 7 years after the previous RCT issue. The first day of the seminar was devoted to new developments in regulation and control (ergonomics aspects, lighting systems, air conditioning in accommodations, solar systems etc..). Stress was put on the revolution expected with the introduction of domestic computer applications and Internet. This first day ended with a precise status of the standardization and future regulatory aspects. The second day was dealing with tele-management and technical management systems for buildings with an analysis of the impact of Internet and of the sensors and actuators capacity in information processing. The consequences and new requirements of the thermal regulation 2000 and the factors of success of a new start-up of the tele-management market in local authorities and social accommodations were analyzed too. (J.S.)

  16. 48 CFR 970.2201-1-3 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 970.2201... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Application of Labor Policies 970.2201-1-3 Contract clause. In addition to the clause at 48 CFR 52.222-1, Notice to the Government of Labor Disputes...

  17. 75 FR 59195 - Federal Acquisition Regulation; Time-and-Materials (T&M) and Labor-Hour (LH) Contracts for...

    Science.gov (United States)

    2010-09-27

    ... audit revealed that, Governmentwide, contracting officers had the mistaken impression that the fixed... FAR. There was a failure of management to detect the lack of compliance with these safeguards. GAO... Office of Management and Budget under 44 U.S.C. Chapter 35, et seq. [[Page 59197

  18. A survey of innovative contracting for quality jobs and ecosystem management.

    Science.gov (United States)

    Cassandra Moseley

    2002-01-01

    This survey identifies and defines innovative contracting mechanisms developed in the Forest Service Pacific Northwest Region and northern California. A survey of nine case studies reveals that several new mechanisms have facilitated ecosystem management, quality jobs, and administrative efficiencies, but at times innovation was hampered by Forest Service institutional...

  19. Review of the Literature on the Changing Psychological Contract: Implications on Career Management and Organizations

    Science.gov (United States)

    Lessner, Ryan; Akdere, Mesut

    2008-01-01

    The changing psychological contract has become a focus for organizational development, especially as job roles within organizations continue to change. This literature review examines the evolving employee-employer relationship and how this relationship has impacted career management and organizations for over the past century. The paper…

  20. 76 FR 76811 - Stakeholders Meeting Regarding Ready Reserve Force (RRF) Ship Manager Contract Program

    Science.gov (United States)

    2011-12-08

    ... Owner/Operator requirement. 12-ship award limit. Definition of Ship Manager ``business entity..., Maritime Security Program, or Tanker Emergency Preparedness Agreement. Small business, sub-contracting vs... affiliation to Rilla Gaither at [email protected] by close of business Monday, December 5, 2011. DATES...

  1. 48 CFR 46.309 - Research and development contracts (short form).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Research and development... REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.309 Research and development contracts... Development (Short Form), in solicitations and contracts for research and development when the clause...

  2. 76 FR 11411 - Defense Federal Acquisition Regulation Supplement; Multiyear Contracting (DFARS Case 2009-D026)

    Science.gov (United States)

    2011-03-02

    ... economic order quantity procurement, are merged into 217.170, General, and 217.172, Multiyear contracts for... guided by the following principles when entering into a multiyear contract for services: (1) The portion... authorized by law (10 U.S.C. 2306b and 10 U.S.C. 2306c). A multiyear supply contract may be authorized by an...

  3. 77 FR 23369 - Federal Acquisition Regulation; Justification and Approval of Sole-Source 8(a) Contracts

    Science.gov (United States)

    2012-04-18

    ... Business Administration (SBA) may not accept a sole- source 8(a) contract in excess of $20 million for... is no conflict with the law. Execution of the J&A prior to the SBA's initiation of contract... small number of businesses that have been awarded 8(a) contracts over the $20 million threshold may be...

  4. 76 FR 4112 - Federal Acquisition Regulation; Submission for OMB Review; Contract Financing

    Science.gov (United States)

    2011-01-24

    ...; Submission for OMB Review; Contract Financing AGENCIES: Department of Defense (DOD), General Services... approved information collection requirement concerning contract financing. A notice was published in the... substantially changed the statutory authorities for Government financing of contracts. Sections 2001(f) and 2051...

  5. Report of the advisory committee on the management and disposition of Ontario Hydro's contracts with non-utility generators

    International Nuclear Information System (INIS)

    Anon.

    1999-01-01

    The report from the advisory committee on the management and disposition of Ontario Hydro's contracts with non-utility generators on the future management and disposition of the power purchase agreements entered into by Ontario Hydro with each non-utility generator (a NUG) is discussed. The integration of NUG contracts into a restructured competitive electricity market, the complexity of the contracts and the disparity of size, resources and approach to the integration exercise of the NUGs produces to an array of challenging issues. The committee identified three alternative strategies for dealing with NUG contracts in Ontario. The first is to use the independent Electricity Market Operator as a purely passive contract holder and above-market cost collection agent. The second is to make the Ontario Electricity Financial Corporation (OEFC) the contract holder and use a commercially oriented manager to administer the NUG contracts. This would minimize above-market costs and to advise on buyouts, compute above-market costs as an amount based on the difference between estimated future contract payments and estimated future market revenues for NUG power and recover them from domestic customers as a part of a single pooled Competition Transfer Charge. The third is to make the OEFC the contract holder, use a commercially oriented manager to administer the NUG contracts, to minimize above-market costs and to advise on buyouts. The OEFC would compute above-market costs as an amount based on the difference between estimated future contract payments and estimated future market revenues for NUG power and recover them from domestic customers as a part of a pooled CTC. The IMO would be used to collect the above-market NUG contract part of the pooled CTC as agent of the contract holder, in a contract uplift that would, like the levy in the first strategy, be charged to wholesale market participants and be included in rates paid by domestic end-use customers.1

  6. Report on Allegation of Unsatisfactory Conditions Regarding Actions by the Defense Contract Management Agency, Earned Value Management Center

    Science.gov (United States)

    2010-07-28

    object ivity of Defen se Contract Management Agency to carry ou t its ea rn ed va lue managemen t oversight responsibilities; and DCMA Response: Non...Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302...Earned Value Management Center Director advised us that the 2-week time frame was “standard operating procedure” for performing compliance reviews at

  7. 77 FR 44059 - Federal Acquisition Regulation; Payments Under Time-and-Materials and Labor-Hour Contracts

    Science.gov (United States)

    2012-07-26

    ... receive more frequent payments than every two weeks. The Contractor shall substantiate vouchers (including...] RIN 9000-AM01 Federal Acquisition Regulation; Payments Under Time-and-Materials and Labor-Hour... the authorization to use time-and-materials and labor-hour contract payment requirements. DATES...

  8. Health, safety, and environmental management system operation in contracting companies: A case study.

    Science.gov (United States)

    Nassiri, Parvin; Yarahmadi, Rasoul; Gholami, Pari Shafaei; Hamidi, Abdolamir; Mirkazemi, Roksana

    2016-05-03

    Systematic and cooperative interactions among parent industry and contractors are necessary for a successful health, safety, and environmental management system (HSE-MS). This study was conducted to evaluate the HSE-MS performance in contracting companies in one of the petrochemical industries in Iran during 2013. Managers of parent and contracting companies participated in this study. The data collection forms included 7 elements of an integrated HSE-MS (leadership and commitment; policy and strategic objectives; organization, resources, and documentation; evaluation and risk management; planning; implementation and monitoring; auditing and reviewing). The results showed that mean percentage of the total scores in seven elements of HSE-MS was 85.7% and 87.0% based on self-report and report of parent company, respectively. In conclusion, this study showed that HSE-MS was desirably functioning; however, improvement to ensure health and safety of workers is still required.

  9. [The Brazilian National Health Surveillance Agency performance evaluation at the management contract model].

    Science.gov (United States)

    Moreira, Elka Maltez de Miranda; Costa, Ediná Alves

    2010-11-01

    The Brazilian National Health Surveillance Agency (Anvisa) is supervised by the Ministry of Health by means of a management contract, a performance evaluation tool. This case study was aimed at describing and analyzing Anvisa's performance evaluation model based on the agency's institutional purpose, according to the following analytical categories: the management contract formalization, evaluation tools, evaluators and institutional performance. Semi-structured interviews and document analysis revealed that Anvisa signed only one management contract with the Ministry of Health in 1999, updated by four additive terms. The Collegiate Board of Directors and the Advisory Center for Strategic Management play the role of Anvisa's internal evaluators and an Assessing Committee, comprising the Ministry of Health, constitutes its external evaluator. Three phases were identified in the evaluation model: the structuring of the new management model (1999-2000), legitimation regarding the productive segment (2001-2004) and widespread legitimation (2005). The best performance was presented in 2000 (86.05%) and the worst in 2004 (40.00%). The evaluation model was shown to have contributed little towards the agency's institutional purpose and the effectiveness measurement of the implemented actions.

  10. The integrated supplier: key to cost management and multi-franchise capitation contracting.

    Science.gov (United States)

    Schuweiler, R C

    1996-05-01

    Capitation...most healthcare providers do not work under it, comprehend it, or even want it, yet supply capitation contracting seminars are popping up everywhere creating the feeling that the bandwagon is leaving, and it might be time to get on board. Not true. Supply capitation is not for all organizations. Capitation contracting is not easy and there are not many successful models to help the uninitiated. If a panacea is sought for reducing supply costs, capitation is only one component of a systematic strategy to reduce materiel costs. This article suggests a direction using the Group Health Materiel Management (Group Health Cooperative of Puget Sound, WA) experience as a point of reference. It advocates a systematic approach that focuses on expense reduction in: cost of goods, holding cost of inventory, labor cost associated with all materiel processes, distribution cost (transportation and par stock pick, pack, and replenishment), product utilization, variation in product standards, and waste stream byproducts. At Group Health (GH) these issues are primarily addressed through the use of: information systems, supplier certification/selection processes, group purchasing compliance, supply channel management, supply capitation contracting programs, standardization, and utilization management. Because of managed care organizational structure, Group Health Cooperative supply capitation contracting, as performed at GH, is discussed not as a quick fix solution but in the spirit of sharing our experience with others who may be considering it as a cost savings tactic in the context of a broad-based materiel management strategy. This article highlights the experiences of GH beginning with materiel management's business process assumptions toward multiple-franchise supply capitation.

  11. The contracting risks of nuclear power engineering and the risk management strategies

    International Nuclear Information System (INIS)

    Ding Shuying

    2010-01-01

    With the trend of professional operation on the nuclear power engineering (thereafter using NPE for short) construction, the companies specialized on NPE whole-contracting are established one after the other, the mode of NPE whole-contracting has been wide adopted domestically. As people always concern for the safety of nuclear power, the risks exposed to NPE contractors are also concerned with the operator, the NPE corporations and the society. Therefore, it is very meaningful to analyze on the risks exposed to NPE contractors and the strategies they should take, for it not only determines whether the NPE construction will be finished on time, but also related to sustainable development of the NPE contracting corporations. The main content of this paper includes the analysis on the features and advantages of NPE whole contracting, the major NPE contracting risks, such as nuclear safety risks, strategic risks, market risks, legal risks, financial risks and operation risks, and the strategies to prevent or to control these risks. The paper focuses on identifying those business processes which risks may frequently take place, and how to manage them, illustrating practice cases to explain the theory, in order to make reference to NPE corporations. (author)

  12. Contract Management Monitoring And Evaluation Of Ghana School Feeding Programme At Atwima Kwanwoma District

    Directory of Open Access Journals (Sweden)

    Andrews Osei Mensah

    2015-08-01

    Full Text Available Ghana School Feeding Programme was introduced at Atwima Kwanwoma District and other parts of the country in 2008 to alleviate hunger and to provide good nutrition for pupils in the public basic schools. Caterers were given contract to provide food to the school pupils on every school-going day under Ghana school feeding programme. Some years have lapsed and there is the need to look back and evaluate this programme taking into consideration the award and management of those contracts. The study also examined how the programme is monitored and evaluated. Data was collected from 80 respondents comprising 29 school pupils and 51 other actors through the use of questionnaire and interview guide It was realised that caterers who are well experience in catering services were awarded contracts based on their past experience and financial abilities through submission of their certificates but not necessarily through bidding. The main component of managing the caterers contract included monitoring payment of debt and problems solving as well as supervision through visiting the schools on quarterly basis. The programme has helped to increase enrolment and retaining pupils in school. It was found out that food giving to the pupils was not served on time not regularly bases and was not sufficient to the pupils as well. The health component of the programme has not been successful as expected. It is recommended that fruits and variety of foods need to be introduced together with de-worming the pupils.

  13. Using SCOR as a Supply Chain Management Framework for Government Agency Contract Requirements

    Science.gov (United States)

    Paxton, Joseph; Tucker, Brian

    2010-01-01

    This paper will present a model that uses the Supply-Chain Operations Reference (SCOR) model as a foundation for a framework to illustrate the information needed throughout a product lifecycle to support a healthy supply chain management function and the subsequent contract requirements to enable it. It will also show where in the supply chain the information must be extracted. The ongoing case study used to exemplify the model is NASA's (National Aeronautics and Space Administration) Ares I program for human spaceflight. Effective supply chain management and contract requirements are ongoing opportunities for continuous improvement within government agencies, specifically development of systems for human spaceflight operations. Multiple reports from the Government Accountability Office (GAO) reinforce this importance. The SCOR model is a framework for describing a supply chain with process building blocks and business activities. It provides a set of metrics for measuring supply chain performance and best practices for continuously improving. This paper expands the application of the SCOR to also provide the framework for defining information needed from different levels of the supply chain and at different phases of the lifecycle. These needs can be incorporated into contracts to enable more effective supply chain management. Depending on the phase of the lifecycle, effective supply chain management will require involvement from different levels of the organization and different levels of the supply chain.

  14. Distinct Skeletal Muscle Gene Regulation from Active Contraction, Passive Vibration, and Whole Body Heat Stress in Humans.

    Science.gov (United States)

    Petrie, Michael A; Kimball, Amy L; McHenry, Colleen L; Suneja, Manish; Yen, Chu-Ling; Sharma, Arpit; Shields, Richard K

    2016-01-01

    Skeletal muscle exercise regulates several important metabolic genes in humans. We know little about the effects of environmental stress (heat) and mechanical stress (vibration) on skeletal muscle. Passive mechanical stress or systemic heat stress are often used in combination with many active exercise programs. We designed a method to deliver a vibration stress and systemic heat stress to compare the effects with active skeletal muscle contraction. The purpose of this study is to examine whether active mechanical stress (muscle contraction), passive mechanical stress (vibration), or systemic whole body heat stress regulates key gene signatures associated with muscle metabolism, hypertrophy/atrophy, and inflammation/repair. Eleven subjects, six able-bodied and five with chronic spinal cord injury (SCI) participated in the study. The six able-bodied subjects sat in a heat stress chamber for 30 minutes. Five subjects with SCI received a single dose of limb-segment vibration or a dose of repetitive electrically induced muscle contractions. Three hours after the completion of each stress, we performed a muscle biopsy (vastus lateralis or soleus) to analyze mRNA gene expression. We discovered repetitive active muscle contractions up regulated metabolic transcription factors NR4A3 (12.45 fold), PGC-1α (5.46 fold), and ABRA (5.98 fold); and repressed MSTN (0.56 fold). Heat stress repressed PGC-1α (0.74 fold change; p muscle contraction. Vibration induced FOXK2 (p muscle contractions. Understanding these responses may assist in developing regenerative rehabilitation interventions to improve muscle cell development, growth, and repair.

  15. Operational Management System for Regulated Water Systems

    Science.gov (United States)

    van Loenen, A.; van Dijk, M.; van Verseveld, W.; Berger, H.

    2012-04-01

    Most of the Dutch large rivers, canals and lakes are controlled by the Dutch water authorities. The main reasons concern safety, navigation and fresh water supply. Historically the separate water bodies have been controlled locally. For optimizating management of these water systems an integrated approach was required. Presented is a platform which integrates data from all control objects for monitoring and control purposes. The Operational Management System for Regulated Water Systems (IWP) is an implementation of Delft-FEWS which supports operational control of water systems and actively gives advice. One of the main characteristics of IWP is that is real-time collects, transforms and presents different types of data, which all add to the operational water management. Next to that, hydrodynamic models and intelligent decision support tools are added to support the water managers during their daily control activities. An important advantage of IWP is that it uses the Delft-FEWS framework, therefore processes like central data collection, transformations, data processing and presentation are simply configured. At all control locations the same information is readily available. The operational water management itself gains from this information, but it can also contribute to cost efficiency (no unnecessary pumping), better use of available storage and advise during (water polution) calamities.

  16. Optimal Management of Supply Disruptions when Contracting with Unreliable, Risk-averse, Suppliers

    OpenAIRE

    Parlane, Sarah; Tsai, Ying-Yi

    2017-01-01

    This paper investigates the optimal management of supply disruptions by a manufacturer who uses order inflation and/or investments in process reliability when contracting two risk-averse suppliers. We consider that these investments can be subject to moral hazard. Technically we solve a newsvendor optimization problem using a random capacity model of disruption. In such a model, the order size does not affect the average production but impacts the probability of disruption. When investments a...

  17. Commitments of Psychological Contracts and Diagnostic Use of Management Control Systems

    OpenAIRE

    Ivan Canan; Gilberto de Andrade Martins; Patrícia Oda

    2016-01-01

    Investigating the commitments the Surveillance Agents from the National Telecommunications Agency (Anatel) made in their psychological contracts and the diagnostic use of the management control system of the entity, this study tested the hypothesis that individuals tend to be more committed to aspects they are charged for within organizations. This is a theoretical and empirical study that assumed that the commitments comprise the part of the belief that individuals develop on reciprocal rela...

  18. 41 CFR 101-1.103 - FPMR temporary regulations.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true FPMR temporary regulations. 101-1.103 Section 101-1.103 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation System § 101...

  19. Pan-European management of electricity portfolios: Risks and opportunities of contract bundling

    International Nuclear Information System (INIS)

    Gampert, Markus; Madlener, Reinhard

    2011-01-01

    Due to the liberalization of energy markets in the European Union, today's European utilities not only focus on electricity supply, but also offer exchange-traded 'structured products' or portfolio management for unbundling financial and physical risk positions. Many utilities are only able to provide these services in their domestic markets. In a globalized economy, the need for a centrally organized pan-European portfolio management has arisen, as it allows a simplified commodity sourcing in combination with an optimized risk management. In this paper, we examine the challenges to be overcome for establishing a European-wide bundling of electricity contracts. For this purpose, a case study based on the business perspective of RWE Supply and Trading in Central and Eastern Europe is carried out. In a first step, we analyze general requirements for a pan-European bundling of electricity contracts. Then, RWE's situation in Europe is examined, based on which we finally propose a concept to meet customer demands in Central and Eastern Europe. - Research highlights: → Analysis of electricity market liberalization in Central and Eastern Europe. → Identification of requirements and problems for pan-European bundling of contracts. → Case study based on RWE Supply and Trading perspective in Central and Eastern Europe. → Model development for pan-European unbundling of financial/physical risk positions.

  20. 77 FR 26232 - Federal Acquisition Regulation; Nondisplacement of Qualified Workers Under Service Contracts

    Science.gov (United States)

    2012-05-03

    ... role. H. Contract clause: The sources of this coverage are section 5 of E.O. 13495 and Appendix A of 29... successor contractor and its subcontractors are required to offer those employees (other than managerial and... managerial and supervisory employees) employed under the predecessor contract whose employment will be...

  1. 75 FR 77733 - Federal Acquisition Regulation; Preventing Abuse of Interagency Contracts

    Science.gov (United States)

    2010-12-13

    ..., including economies and efficiencies and the ability to leverage resources. This interim rule, which...) Describe the impact such contract will have on the ability of the Government to leverage its purchasing power, e.g., will it have a negative effect because it dilutes other existing contracts; (4) Include an...

  2. Implementation of the best in class project management and contract management initiative at the Department Of Energy's Office Of Environmental Management - 16062

    International Nuclear Information System (INIS)

    Van Camp, Scott G.; Stevenson, Jeremy S.; Deiters, Michael G.; Jamison, Timothy P.

    2009-01-01

    Since its creation in 1989, the Department of Energy (DOE), Office of Environmental Management (EM) has struggled with a legacy of inadequate project management and contract management. This has been manifested in recurring scope changes, cost overruns and schedule delays, and has been documented in multiple internal and external reviews. EM has committed itself to improving project performance and undertaken a number of proactive management initiatives including the development of a 'Best in Class' Project Management and Contract Management organization (i.e., the BICPM Initiative). During 2007, EM assessed the status of project management and contract management at 15 EM sites. These assessments evaluated strengths and weaknesses in 12 key project management capabilities and three contract management benchmarks. The January 2008 Compilation Assessment Report showed that EM faces significant challenges in its mission execution due to staffing shortages, project and contract management integration, insufficient project-oriented culture, and lack of a clear role for Headquarters in BICPM. EM then formulated a strategy to meet their objectives in the March 2008 Corporate Implementation Plan. It summarizes BICPM efforts, introduces the vision for BICPM, identifies the strategy for achieving BICPM, and describes a process for implementing BICPM. That is, it acts as a road-map to address EM's challenges. It also documents 18 Recommended Priority Actions (RPAs) that are the key to correcting these challenges. These RPAs provide a clear path forward that can be communicated to the entire EM organization and provide the foundation upon which a BICPM culture can be built. EM has since gained considerable momentum and progress towards institutionalizing BICPM. This paper provides a discussion of the BICPM Initiative and its implementation. (authors)

  3. The Analysis of the Pre-Emption Right under the Contract of Sale in the Regulation of New Civil Code

    Directory of Open Access Journals (Sweden)

    Mirela Costache

    2011-05-01

    Full Text Available In this paper we will keep under review the specificity of the reported pre-emption right to the sale contract, according to the article 1730-1740 of the New Civil Code. With the entry into force of the new future regulation, the pre-emption right will acquire a separate status, being currently known that the legal status of the right under the review is diverse; there are many legal provisions which provide this right in various areas, being excedentary to the sale contract, such as culture, privatization, franchising, intellectual property. According to the analysis of the future legal deposition, it shows that pre-emption right may have as a source both the law and the contract, in this case it is referred to the legal and conventional right of pre-emption. We note also that, in light of the new regulations, the mechanism for exercising the right of pre-emption is similar to the one applicable to the right of preference. Objectives: The purpose of this paper is to focus on the usefulness of this new legislative measure designed to establish a proper legal support specific to the holder of this right in the conclusion of a contract in relation to third parties. Approach: This topic emphasizes the use of the following methods: observation, comparison and interpretation of laws.

  4. Skeletal myofiber VEGF regulates contraction-induced perfusion and exercise capacity but not muscle capillarity in adult mice.

    Science.gov (United States)

    Knapp, Amy E; Goldberg, Daniel; Delavar, Hamid; Trisko, Breanna M; Tang, Kechun; Hogan, Michael C; Wagner, Peter D; Breen, Ellen C

    2016-07-01

    A single bout of exhaustive exercise signals expression of vascular endothelial growth factor (VEGF) in the exercising muscle. Previous studies have reported that mice with life-long deletion of skeletal myofiber VEGF have fewer capillaries and a severe reduction in endurance exercise. However, in adult mice, VEGF gene deletion conditionally targeted to skeletal myofibers limits exercise capacity without evidence of capillary regression. To explain this, we hypothesized that adult skeletal myofiber VEGF acutely regulates skeletal muscle perfusion during muscle contraction. A tamoxifen-inducible skeletal myofiber-specific VEGF gene deletion mouse (skmVEGF-/-) was used to reduce skeletal muscle VEGF protein by 90% in adult mice. Three weeks after inducing deletion of the skeletal myofiber VEGF gene, skmVEGF-/- mice exhibited diminished maximum running speed (-10%, P Contraction-induced perfusion measured by optical imaging during a period of electrically stimulated muscle contraction was 85% lower in skmVEGF-/- than control mice. No evidence of capillary rarefication was detected in the soleus, gastrocnemius, and extensor digitorum longus (EDL) up to 8 wk after tamoxifen-induced VEGF ablation, and contractility and fatigue resistance of the soleus measured ex vivo were also unchanged. The force-frequency of the EDL showed a small right shift, but fatigue resistance did not differ between EDL from control and skmVEGF-/- mice. These data suggest myofiber VEGF is required for regulating perfusion during periods of contraction and may in this manner affect endurance capacity. Copyright © 2016 the American Physiological Society.

  5. Two staged incentive contract focused on efficiency and innovation matching in critical chain project management

    Directory of Open Access Journals (Sweden)

    Min Zhang

    2014-09-01

    Full Text Available Purpose: The purpose of this paper is to define the relative optimal incentive contract to effectively encourage employees to improve work efficiency while actively implementing innovative behavior. Design/methodology/approach: This paper analyzes a two staged incentive contract coordinated with efficiency and innovation in Critical Chain Project Management using learning real options, based on principle-agent theory. The situational experiment is used to analyze the validity of the basic model. Finding: The two staged incentive scheme is more suitable for employees to create and implement learning real options, which will throw themselves into innovation process efficiently in Critical Chain Project Management. We prove that the combination of tolerance for early failure and reward for long-term success is effective in motivating innovation. Research limitations/implications: We do not include the individual characteristics of uncertain perception, which might affect the consistency of external validity. The basic model and the experiment design need to improve. Practical Implications: The project managers should pay closer attention to early innovation behavior and monitoring feedback of competition time in the implementation of Critical Chain Project Management. Originality/value: The central contribution of this paper is the theoretical and experimental analysis of incentive schemes for innovation in Critical Chain Project Management using the principal-agent theory, to encourage the completion of CCPM methods as well as imitative free-riding on the creative ideas of other members in the team.

  6. Frontiers of environmental regulation: environmental management systems: a regulator`s perspective

    Energy Technology Data Exchange (ETDEWEB)

    Stone, M.J. [South Australian Dept. of Mines and Energy, Adelaide, SA (Australia)

    1996-12-31

    Leading edge companies throughout the world have embraced management systems to achieve optimal sustainable performance in the ever changing business environment of the 1990s. Given that the natural environment and environmental performance have become major issues affecting organizations, the need for integrating environmental management with all the other components of an organization`s overall management approach is now widely recognized. This paper is organized in five parts. The first explores recently released environmental standards, the interim environmental management systems (EMS) general guidelines standard AS/NZS ISO 14004 (Int) and identifies how this has dealt with the regulator/community/company interface. The second identifies company requirements for addressing environmental issues. The third, considers regulatory theory to identify current requirements for an effective regulatory system and how this can interface with a company`s EMS. These form the basis in the fourth section for identifying some opportunities which occur at the company/ regulator interface. The fifth and final section draws a number of conclusions about the current frontiers of environmental regulation. The coincidence of the requirements of a regulatory framework with the areas of interface between what is referred to in the draft International Standard for EMS as `Interested Parties`, the regulators and community, are identified. (author). 1 tab., 2 figs., 20 refs.

  7. Distinct Skeletal Muscle Gene Regulation from Active Contraction, Passive Vibration, and Whole Body Heat Stress in Humans.

    Directory of Open Access Journals (Sweden)

    Michael A Petrie

    Full Text Available Skeletal muscle exercise regulates several important metabolic genes in humans. We know little about the effects of environmental stress (heat and mechanical stress (vibration on skeletal muscle. Passive mechanical stress or systemic heat stress are often used in combination with many active exercise programs. We designed a method to deliver a vibration stress and systemic heat stress to compare the effects with active skeletal muscle contraction.The purpose of this study is to examine whether active mechanical stress (muscle contraction, passive mechanical stress (vibration, or systemic whole body heat stress regulates key gene signatures associated with muscle metabolism, hypertrophy/atrophy, and inflammation/repair.Eleven subjects, six able-bodied and five with chronic spinal cord injury (SCI participated in the study. The six able-bodied subjects sat in a heat stress chamber for 30 minutes. Five subjects with SCI received a single dose of limb-segment vibration or a dose of repetitive electrically induced muscle contractions. Three hours after the completion of each stress, we performed a muscle biopsy (vastus lateralis or soleus to analyze mRNA gene expression.We discovered repetitive active muscle contractions up regulated metabolic transcription factors NR4A3 (12.45 fold, PGC-1α (5.46 fold, and ABRA (5.98 fold; and repressed MSTN (0.56 fold. Heat stress repressed PGC-1α (0.74 fold change; p < 0.05; while vibration induced FOXK2 (2.36 fold change; p < 0.05. Vibration similarly caused a down regulation of MSTN (0.74 fold change; p < 0.05, but to a lesser extent than active muscle contraction. Vibration induced FOXK2 (p < 0.05 while heat stress repressed PGC-1α (0.74 fold and ANKRD1 genes (0.51 fold; p < 0.05.These findings support a distinct gene regulation in response to heat stress, vibration, and muscle contractions. Understanding these responses may assist in developing regenerative rehabilitation interventions to improve muscle cell

  8. Audit Report on Management Controls over the Use of Service Contracts at the Office of River Protection

    International Nuclear Information System (INIS)

    2009-01-01

    . Specifically, ORP allowed PAC employees to perform work that was inherently governmental and created situations where a potential conflict of interest occurred. Specifically: (1) ORP assigned PAC employees responsibility for providing information and responses to Congressional inquiries and reports issued by the GAO and the Department of Energy's Office of Inspector General (OIG); and (2) PAC employees were also allowed to perform functions that created potential conflicts of interest. ORP permitted PAC employees, for example, to develop statements of work and approve funding of work to be performed under PAC's own contract. We concluded that these problems occurred, at least in part, because ORP had not established controls necessary to effectively administer the PAC contract. Federal procurement regulations recommended that agencies provide additional management controls over contractors whose work has the potential to influence the action of government officials. ORP, however, had not implemented the controls specifically recommended in Federal policy guidance for administering contracts, including: (1) Performing conflict of interest reviews; and (2) Separating contractor and Department employees either physically or organizationally. By not effectively administering its contract with PAC, ORP increased the risk that decisions based on work performed by the contractor may not have been made in the best interests of the Department. For example, ORP increased the risk that approved work would be unnecessary or too costly. As we also recently noted in our report on 'Management Challenges at the Department of Energy' (DOE/IG-0808, December 2008), contract administration issues such as those discussed in this report remain a significant vulnerability. Continued efforts to improve this area are vitally important since the risk that contractors receive payments for unallowable costs could also increase as the Department expands its contracting activities under the American

  9. Development of regulations and trading practices relating to fuel supply contracts

    International Nuclear Information System (INIS)

    Poggi, C.; Paoletti Gualandi, M.; Sartorelli, C.

    1983-01-01

    This paper recalls that the construction of new nuclear plants is undergoing substantial delays in many countries as compared with initial programmes, thus resulting in an excess of enriched uranium and enrichment services on the world market. This has compelled operators to take action to reduce, at least in part, the costs incurred by large financial lockups. The only feasible solution regarding enrichment contracts has been to assign those contracts to other operators or enter into a second contract to have the latter utilize such enrichment services. (NEA) [fr

  10. AMP-activated protein kinase in contraction regulation of skeletal muscle metabolism: necessary and/or sufficient?

    DEFF Research Database (Denmark)

    Jensen, Thomas Elbenhardt; Wojtaszewski, Jørgen; Richter, Erik

    2009-01-01

    In skeletal muscle, the contraction-activated heterotrimeric 5'-AMP-activated protein kinase (AMPK) protein is proposed to regulate the balance between anabolic and catabolic processes by increasing substrate uptake and turnover in addition to regulating the transcription of proteins involved...... in mitochondrial biogenesis and other aspects of promoting an oxidative muscle phenotype. Here, the current knowledge on the expression of AMPK subunits in human quadriceps muscle and evidence from rodent studies suggesting distinct AMPK subunit expression pattern in different muscle types is reviewed. Then......, the intensity and time dependence of AMPK activation in human quadriceps and rodent muscle are evaluated. Subsequently, a major part of this review critically examines the evidence supporting a necessary and/or sufficient role of AMPK in a broad spectrum of skeletal muscle contraction-relevant processes...

  11. The regulation of transportation contracts for natural gas: the issue of contractual dirigisme; A regulacao dos contratos de transporte de gas natural: a questao do dirigismo contratual

    Energy Technology Data Exchange (ETDEWEB)

    Queiroz, Lizziane Souza; Siqueira, Mariana; Vasconcellos, Mariana Vannucci [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil)

    2004-07-01

    The old principals that that rules the liberal idea of contract are replaced for a new Theory that allows the State to interfere in the private sector to please the public interest. The Gas Transport Contract has the influence of open access and its public regulation is necessary to provide the most important needs of Brazilian market. After this word about the problem, we realize the meaning of the public intervention on the Transport Contracts to protect the nation's interests and to limit the private power. This paper try to clear the meaning of the contracts regulation to the gas natural market and its influence in a Brazilian interests. (author)

  12. A decision-making framework to integrate maintenance contract conditions with critical spares management

    International Nuclear Information System (INIS)

    Godoy, David R.; Pascual, Rodrigo; Knights, Peter

    2014-01-01

    Maintenance outsourcing is a strategic driver for asset intensive industries pursuing to enhance supply chain performance. Spare parts management plays a relevant role in this premise since its significant impact on equipment availability, and hence on business success. Designing critical spares policies might therefore seriously affect maintenance contracts profitability, yet service receivers and external providers traditionally attempt to benefit separately. To coordinate both chain parties, we investigated whether the spare components pool should be managed in-house or contracted out. This paper provides a decision-making framework to efficiently integrate contractual conditions with critical spares stockholding. Using an imperfect maintenance strategy over a finite horizon, the scheme maximizes chain returns whilst evaluating the impact of an additional part to stock. As result, an original joint value – preventive interval and stock level – sets the optimal agreement to profitably allocate the components pool within the service contract. Subsidization bonuses on preventive interventions and pooling costs are also estimated to induce the service provider to adjust its policy when needed. The proposed contractual conditions motivate stakeholders to continuously improve maintenance performance and supply practices, thus obtaining higher joint benefits

  13. 77 FR 75766 - Federal Acquisition Regulation; Nondisplacement of Qualified Workers Under Service Contracts

    Science.gov (United States)

    2012-12-21

    ... invention, imagination, originality or talent in a recognized field of artistic or creative endeavor'' (29... recommended the final rule include language allowing contracting officers to submit a negative performance...

  14. Use of Federal Acquisition Regulation. Part 12. Contracts for Applied Research

    National Research Council Canada - National Science Library

    2001-01-01

    ...) Part 12, "Acquisition of Commercial Items,"contracts for acquiring applied research. Applied research involves the scientific efforts to translate basic research into solutions for broadly defined military needs...

  15. Administrative contracts

    Directory of Open Access Journals (Sweden)

    Vukićević-Petković Milica

    2015-01-01

    Full Text Available Administrative contracts are a special type of contract where usually one of the contracting parties is a public law body and which is concluded for the performance of public service and the realization of a public interest. They go a long way since its inception to its eventual final acceptance of all the legal systems. One of the enduring characteristics of this type of contract is their disquised or unnoticed existence. This is why only monitoring their development may lead to a complete understanding of the importance and essence of this institution as well as the need for its complete legal regulation.

  16. Electrical contracting

    CERN Document Server

    Neidle, Michael

    2013-01-01

    Electrical Contracting, Second Edition is a nine-chapter text guide for the greater efficiency in planning and completing installations for the design, installation and control of electrical contracts. This book starts with a general overview of the efficient cabling and techniques that must be employed for safe wiring design, as well as the cost estimation of the complete electrical contract. The subsequent chapters are devoted to other electrical contracting requirements, including electronic motor control, lighting, and electricity tariffs. A chapter focuses on the IEE Wiring Regulations an

  17. Report: Policies Needed for Proper Use and Management of Cost-Reimbursement Contracts Based on Duncan Hunter Act

    Science.gov (United States)

    Report #12-P-0320, March 6, 2012. EPA did not comply with several key revisions to the FAR as amended by the interim rule, Proper Use and Management of Cost Reimbursement Contracts (FAR Case 2008-030).

  18. Metabolic regulation of collagen gel contraction by porcine aortic valvular interstitial cells

    Science.gov (United States)

    Kamel, Peter I.; Qu, Xin; Geiszler, Andrew M.; Nagrath, Deepak; Harmancey, Romain; Taegtmeyer, Heinrich; Grande-Allen, K. Jane

    2014-01-01

    Despite a high incidence of calcific aortic valve disease in metabolic syndrome, there is little information about the fundamental metabolism of heart valves. Cell metabolism is a first responder to chemical and mechanical stimuli, but it is unknown how such signals employed in valve tissue engineering impact valvular interstitial cell (VIC) biology and valvular disease pathogenesis. In this study porcine aortic VICs were seeded into three-dimensional collagen gels and analysed for gel contraction, lactate production and glucose consumption in response to manipulation of metabolic substrates, including glucose, galactose, pyruvate and glutamine. Cell viability was also assessed in two-dimensional culture. We found that gel contraction was sensitive to metabolic manipulation, particularly in nutrient-depleted medium. Contraction was optimal at an intermediate glucose concentration (2 g l−1) with less contraction with excess (4.5 g l−1) or reduced glucose (1 g l−1). Substitution with galactose delayed contraction and decreased lactate production. In low sugar concentrations, pyruvate depletion reduced contraction. Glutamine depletion reduced cell metabolism and viability. Our results suggest that nutrient depletion and manipulation of metabolic substrates impacts the viability, metabolism and contractile behaviour of VICs. Particularly, hyperglycaemic conditions can reduce VIC interaction with and remodelling of the extracellular matrix. These results begin to link VIC metabolism and macroscopic behaviour such as cell–matrix interaction. PMID:25320066

  19. Low-level radioactive waste management: French and foreign regulations

    International Nuclear Information System (INIS)

    Coulon, R.

    1991-01-01

    This paper describes radioactive waste management regulations applied in USA, CANADA, SCANDINAVIA and FRANCE. For low level radioactive wastes, it is necessary to adapt waste management regulations which were firt definite for high level radioactive wastes. So the exemption concept is a simplification method of regulations applied to low radiation sources

  20. 48 CFR 970.2307-2 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... Vehicle Fleet Fuel Efficiency, in all management contracts providing for Contractor management of the motor vehicle fleet. [68 FR 52131, Sept. 2, 2003] Effective Date Note: At 75 FR 57695, Sept. 22, 2010... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Environment, Energy and Water Efficiency...

  1. 76 FR 81408 - Contractor Legal Management Requirements; Acquisition Regulations

    Science.gov (United States)

    2011-12-28

    ... DEPARTMENT OF ENERGY 10 CFR Part 719 48 CFR Parts 931, 952 and 970 RIN 1990-AA37 Contractor Legal... Energy (DOE or Department) is proposing to revise existing regulations covering contractor legal... costs by certain contractors whose contracts exceed $100,000,000 as well as legal counsel retained...

  2. 78 FR 25795 - Contractor Legal Management Requirements; Acquisition Regulations

    Science.gov (United States)

    2013-05-03

    ... DEPARTMENT OF ENERGY 10 CFR Part 719 48 CFR Parts 931, 952, and 970 RIN 1990-AA37 Contractor Legal.... ACTION: Final rule. SUMMARY: The Department of Energy revises existing regulations covering contractor... costs by certain contractors whose contracts exceed $100,000,000 as well as legal counsel retained...

  3. Regulation of Contraction by the Thick Filaments in Skeletal Muscle.

    Science.gov (United States)

    Irving, Malcolm

    2017-12-19

    Contraction of skeletal muscle cells is initiated by a well-known signaling pathway. An action potential in a motor nerve triggers an action potential in a muscle cell membrane, a transient increase of intracellular calcium concentration, binding of calcium to troponin in the actin-containing thin filaments, and a structural change in the thin filaments that allows myosin motors from the thick filaments to bind to actin and generate force. This calcium/thin filament mediated pathway provides the "START" signal for contraction, but it is argued that the functional response of the muscle cell, including the speed of its contraction and relaxation, adaptation to the external load, and the metabolic cost of contraction is largely determined by additional mechanisms. This review considers the role of the thick filaments in those mechanisms, and puts forward a paradigm for the control of contraction in skeletal muscle in which both the thick and thin filaments have a regulatory function. The OFF state of the thick filament is characterized by helical packing of most of the myosin head or motor domains on the thick filament surface in a conformation that makes them unavailable for actin binding or ATP hydrolysis, although a small fraction of the myosin heads are constitutively ON. The availability of the majority fraction of the myosin heads for contraction is controlled in part by the external load on the muscle, so that these heads only attach to actin and hydrolyze ATP when they are required. This phenomenon seems to be the major determinant of the well-known force-velocity relationship of muscle, and controls the metabolic cost of contraction. The regulatory state of the thick filament also seems to control the dynamics of both muscle activation and relaxation. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  4. Managing water utility financial risks through third-party index insurance contracts

    Science.gov (United States)

    Zeff, Harrison B.; Characklis, Gregory W.

    2013-08-01

    As developing new supply capacity has become increasingly expensive and difficult to permit (i.e., regulatory approval), utilities have become more reliant on temporary demand management programs, such as outdoor water use restrictions, for ensuring reliability during drought. However, a significant fraction of water utility income is often derived from the volumetric sale of water, and such restrictions can lead to substantial revenue losses. Given that many utilities set prices at levels commensurate with recovering costs, these revenue losses can leave them financially vulnerable to budgetary shortfalls. This work explores approaches for mitigating drought-related revenue losses through the use of third-party financial insurance contracts based on streamflow indices. Two different types of contracts are developed, and their efficacy is compared against two more traditional forms of financial hedging used by water utilities: Drought surcharges and contingency funds (i.e., self-insurance). Strategies involving each of these approaches, as well as their use in combination, are applied under conditions facing the water utility serving Durham, North Carolina. A multireservoir model provides information on the scale and timing of droughts, and the financial effects of these events are simulated using detailed data derived from utility billing records. Results suggest that third-party index insurance contracts, either independently or in combination with more traditional hedging tools, can provide an effective means of reducing a utility's financial vulnerability to drought.

  5. Coalition contract management as a systems change strategy for HIV prevention.

    Science.gov (United States)

    Darrow, William W; Montanea, Julie E; Sánchez-Braña, Elizabeth

    2010-11-01

    Racial and Ethnic Approaches to Community Health (REACH) 2010 provided a unique opportunity for minority community-based organizations (CBOs) to work together to eliminate disparities in HIV disease. A coalition was formed in Broward County to respond to the REACH 2010 program announcement, a university was chosen to coordinate efforts, and contracts were negotiated with CBO partners to develop, implement, and evaluate a community action plan. Contract management provided stability, focus, and a mechanism for coalition partners to measure progress toward achieving project objectives. By emphasizing documentation as well as the delivery of services, however, contract conditions also placed a heavy burden on educational outreach workers, restricted the reimbursable activities of member organizations, and created friction between minority agencies and university staff. Although the coalition met many of its objectives, the introduction and enforcement of a mutually agreed on set of rules and obligations as a way of promoting systems change in Broward County failed to make a lasting impact among community partners. CBOs continued to compete with one another for HIV prevention project funding and stopped collaborating as closely with another when federal support for our REACH 2010 community demonstration project ran out.

  6. River Protection Project: Interface Management in the Multi Contract Project Environment at Hanford

    International Nuclear Information System (INIS)

    SHIKASHIO, L.A.

    2000-01-01

    The Office of River Protection (ORP) is implementing the River Protection Project (RPP) using two prime contractors. CH2M Hill Hanford Group, Inc. (CHG) is responsible for operating the existing tank system, delivering the waste feed to the waste treatment plant, and managing the resulting low- and high-level glass waste ''product'' through a performance-based fee type contract. A separate prime contractor will be responsible for designing, constructing and commissioning of a new Waste Treatment and Immobilization Plant (WTP), and preparing the waste for ultimate disposal. In addition to the prime contractors and their interfaces, the River Protection Project is being conducted on the Hanford Site, which is under the management of another DOE organization, DOE Richland Field Office (DOE-RL). The infrastructure and utilities are provided by DOE-RL, for example. In addition, there are multiple other technical interfaces with federal, state and other regulatory agencies that influence the management of the activities. This paper provides an overview of the approach employed by ORP to identify, coordinate, and manage the technical interfaces of RPP. In addition, this paper describes the approach and methodologies used to: Establish an overall framework for interface management. Establish the requirements for defining and managing interfaces for the prime contractors and DOE. Contractually requiring the prime contractors to control and manage the interfaces

  7. Tools for Closure Project and Contract Management: Development of the Rocky Flats Integrated Closure Project Baseline

    International Nuclear Information System (INIS)

    Gelles, C. M.; Sheppard, F. R.

    2002-01-01

    This paper details the development of the Rocky Flats Integrated Closure Project Baseline - an innovative project management effort undertaken to ensure proactive management of the Rocky Flats Closure Contract in support of the Department's goal for achieving the safe closure of the Rocky Flats Environmental Technology Site (RFETS) in December 2006. The accelerated closure of RFETS is one of the most prominent projects within the Department of Energy (DOE) Environmental Management program. As the first major former weapons plant to be remediated and closed, it is a first-of-kind effort requiring the resolution of multiple complex technical and institutional challenges. Most significantly, the closure of RFETS is dependent upon the shipment of all special nuclear material and wastes to other DOE sites. The Department is actively working to strengthen project management across programs, and there is increasing external interest in this progress. The development of the Rocky Flats Integrated Closure Project Baseline represents a groundbreaking and cooperative effort to formalize the management of such a complex project across multiple sites and organizations. It is original in both scope and process, however it provides a useful precedent for the other ongoing project management efforts within the Environmental Management program

  8. Managing in the Regulatory Thicket : Regulation Legitimacy and Expertise

    NARCIS (Netherlands)

    Amirkhanyan, Anna A.; Meier, Kenneth J.; O'Toole, Laurence J.

    Although the influence of government regulation on organizations is undeniable, empirical research in this field is scarce. This article investigates how the understanding of and attitudes toward government regulation among public, nonprofit, and for-profit managers affect organizational

  9. State health managers' perceptions of the Public Health Action Organizational Contract in the State of Ceará, Brazil.

    Science.gov (United States)

    Goya, Neusa; Andrade, Luiz Odorico Monteiro de; Pontes, Ricardo José Soares; Tajra, Fábio Solon; Barreto, Ivana Cristina de Holanda Cunha

    2017-04-01

    The Public Health Action Organizational Contract (COAP) / Decree 7.508/2011 aimed to seal health agreements made between federated entities to promote the cooperative governance and management of Health Regions. A qualitative study was carried out adopting a hermeneutic approach to understand state health managers' perceptions of the elaboration and effects of the COAP in the State of Ceará. Open-ended interviewees and documental analysis were conducted. It was observed that the COAP led to the strengthening of regionalization in the government sphere; institutional gains through the implementation of ombudsmen and the National System of Pharmaceutical Care Management; increased information about the state health system's workforce; and health budget transparency. The following problems were (re)visited: institutional weakness in the operation of the network; limited state capacity for regulation of care; and underfunding. Regional governance was restricted to the government sphere, coordinated by the state, and was characterized by a predominantly bureaucratic and hierarchical governance structure. The COAP inaugurated a contractual interfederative model of regionalization, but revealed the institutional weaknesses of the SUS and its lacks of capacity to fulfill its principles as the structural problems of the three-tiered model go unaddressed.

  10. Long-term contract auctions and market power in regulated power industries

    International Nuclear Information System (INIS)

    Soledad Arellano, M.; Serra, Pablo

    2010-01-01

    A number of countries with oligopolistic power industries have used marginal cost pricing to set the price of energy for small customers. This course of action, however, does not necessarily ensure an efficient outcome when competition is imperfect. The purpose of this paper is to study how the auction of long-term contracts could reduce market power. We do so in a two-firm, two-technology, linear-cost, static model where demand is summarized by a price inelastic load curve. In this context we show that the larger the proportion of total demand auctioned in advance, the lower are both the contract and the average spot price of energy.

  11. Contract-Based Transaction Management in Cross-Organizational Workflow Management

    NARCIS (Netherlands)

    Grefen, P.W.P.J.

    Cross-organizational workflow management is an essential ingredient for process integration in virtual enterprises. To obtain cross-organizational workflow processes with robust semantics, these processes should be supported by highlevel cross-organizational transaction management. In this context,

  12. Learning in a self-managed management career : the relation between managers' HRD-patterns, psychological career contracts and mobility perpectives

    NARCIS (Netherlands)

    Lankhuijzen, E.S.K.

    2002-01-01

    This thesis focuses on the significance of managers HRD-activities (learning activities) in modern career contexts. Based on literature study and several pre-studies, a conceptual research model was developed containing three main elements: HRD-pattern, psychological career contract and mobility

  13. 76 FR 31410 - Federal Acquisition Regulation; Prohibition on Contracting With Inverted Domestic Corporations

    Science.gov (United States)

    2011-05-31

    ... with the tax code. The respondent cites both 6 U.S.C. 395 and 26 U.S.C. 7874, because they both require... offshore and also risked contracting officers reaching disparate conclusions. For these reasons, and the..., Regulatory Planning and Review dated September 30, 1993. This rule is not a major rule under 5 U.S.C. 804. IV...

  14. 75 FR 18034 - Defense Federal Acquisition Regulation Supplement; Research and Development Contract Type...

    Science.gov (United States)

    2010-04-08

    ... Budget under 44 U.S.C. 3501, et seq. List of Subjects in 48 CFR Parts 234 and 235 Government procurement...). ACTION: Final rule. SUMMARY: DoD is adopting as final, without change, an interim rule that requires the Milestone Decision Authority (MDA) for a major defense acquisition program (MDAP) to select the contract...

  15. 76 FR 14587 - Defense Federal Acquisition Regulation Supplement; Multiyear Contract Authority for Electricity...

    Science.gov (United States)

    2011-03-17

    ... cost effectiveness of the proposed purchase has been made based upon a business case analysis, and (2... determined, on the basis of a business case analysis prepared by DoD, that-- (1) The proposed purchase of electricity under such contract is cost effective; and (2) It would not be possible to purchase electricity...

  16. Quality management in the regulation of radioactive material transport

    International Nuclear Information System (INIS)

    Barenghi, Leonardo; Capadona, Nancy M.; Lopez Vietri, Jorge R.; Panzino, Marina; Ceballos, Jorge

    2006-01-01

    The paper describes the quality management procedure used by the Argentine Nuclear Regulatory Authority to establish the regulations concerning the safe transport of radioactive materials. The quality management system is based on the family of the ISO 9000 norms [es

  17. Managing and regulating organisational change in nuclear installations

    International Nuclear Information System (INIS)

    Pyy, P.; Reiersen, C.

    2004-01-01

    To the extent that organisational change in nuclear installations can potentially impact nuclear safety, it is imperative to ensure that such change is property managed and regulated. A number of key elements can help achieve successful management of change. (author)

  18. The evolving local social contract for managing climate and disaster risk in Vietnam.

    Science.gov (United States)

    Christoplos, Ian; Ngoan, Le Duc; Sen, Le Thi Hoa; Huong, Nguyen Thi Thanh; Lindegaard, Lily Salloum

    2017-07-01

    How do disasters shape local government legitimacy in relation to managing climate- and disaster-related risks? This paper looks at how local authorities in Central Vietnam perceive their social contract for risk reduction, including the partial merging of responsibilities for disaster risk management with new plans for and investments in climate change adaptation and broader socioeconomic development. The findings indicate that extreme floods and storms constitute critical junctures that stimulate genuine institutional change. Local officials are proud of their strengthened role in disaster response and they are eager to boost investment in infrastructure. They have struggled to reinforce their legitimacy among their constituents, but given the shifting roles of the state, private sector, and civil society, and the undiminished emphasis on high-risk development models, their responsibilities for responding to emerging climate change scenarios are increasingly nebulous. The past basis for legitimacy is no longer valid, but tomorrow's social contract is not yet defined. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

  19. 48 CFR 46.307 - Fixed-price research and development contracts.

    Science.gov (United States)

    2010-10-01

    ... REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.307 Fixed-price research and development... Development—Fixed-Price, in solicitations and contracts for research and development when (1) the primary... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Fixed-price research and...

  20. 48 CFR 46.308 - Cost-reimbursement research and development contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cost-reimbursement... ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.308 Cost-reimbursement... of Research and Development—Cost-Reimbursement, in solicitations and contracts for research and...

  1. Tetraspanin CD9 regulates cell contraction and actin arrangement via RhoA in human vascular smooth muscle cells.

    Directory of Open Access Journals (Sweden)

    Michael J Herr

    Full Text Available The most prevalent cardiovascular diseases arise from alterations in vascular smooth muscle cell (VSMC morphology and function. Tetraspanin CD9 has been previously implicated in regulating vascular pathologies; however, insight into how CD9 may regulate adverse VSMC phenotypes has not been provided. We utilized a human model of aortic smooth muscle cells to understand the consequences of CD9 deficiency on VSMC phenotypes. Upon knocking down CD9, the cells developed an abnormally small and rounded morphology. We determined that this morphological change was due to a lack of typical parallel actin arrangement. We also found similar total RhoA but decreased GTP-bound (active RhoA levels in CD9 deficient cells. As a result, cells lacking a full complement of CD9 were less contractile than their control treated counterparts. Upon restoration of RhoA activity in the CD9 deficient cells, the phenotype was reversed and cell contraction was restored. Conversely, inhibition of RhoA activity in the control cells mimicked the CD9-deficient cell phenotype. Thus, alteration in CD9 expression was sufficient to profoundly disrupt cellular actin arrangement and endogenous cell contraction by interfering with RhoA signaling. This study provides insight into how CD9 may regulate previously described vascular smooth muscle cell pathophysiology.

  2. 41 CFR 101-26.508-1 - Requisitioning data processing tape available through Federal Supply Schedule contracts.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Requisitioning data... Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26-PROCUREMENT SOURCES AND PROGRAM 26.5-GSA Procurement Programs § 101-26...

  3. 41 CFR 101-26.508-2 - Requisitioning data processing tape not available from Federal Supply Schedule contracts.

    Science.gov (United States)

    2010-07-01

    ... Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26-PROCUREMENT SOURCES AND PROGRAM 26.5-GSA Procurement... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Requisitioning data...

  4. Brief considerations on the acquisition of works of art in the European regulation of public contracts

    Directory of Open Access Journals (Sweden)

    Pierpaolo Forte

    2017-11-01

    Full Text Available The work, renouncing to a precise definition of art, acknowledges that there are art objects and cultural objects, which, in this way, are relevant also in legal terms, and try to advance some reflections on the relevance of art in relation to the European discipline of public contracts and, in particular, what can be deduced from Directive 2014/24 / EU, which can well be understood as a sort of cultural sign that can provide insights into how art is perceived in Europe, even in political terms, in this historical phase. The paper therefore examines the use of negotiated procedures without prior publication of a contract notice, for the «creation or acquisition of a unique work of art or artistic performance», and to do so faces the problem of the object of the procurement by “contracting authorities” which deals with things or performances (works, supplies or services relating to artistic products, by examining the needs which a public administration may have in relation to obtaining the availability of a work of art, and the different modes of this type of acquisition. Finally, the study examines the theme of «art exhibitions», trying to prove that they are autonomous objects, which are represented in the European directive under the diction «artistic performance».

  5. 78 FR 29247 - Contractor Legal Management Requirements; Acquisition Regulations; Correction

    Science.gov (United States)

    2013-05-20

    ... DEPARTMENT OF ENERGY 48 CFR Part 952 RIN 1990-AA37 Contractor Legal Management Requirements; Acquisition Regulations; Correction AGENCY: Department of Energy. ACTION: Final rule; correction. SUMMARY: The... (78 FR 25795). In this document, DOE revised existing regulations covering contractor legal management...

  6. Regulation of basal tone, relaxation and contraction of the lower oesophageal sphincter. Relevance to drug discovery for oesophageal disorders.

    Science.gov (United States)

    Farré, R; Sifrim, D

    2008-03-01

    The lower oesophageal sphincter (LOS) is a specialized region of the oesophageal circular smooth muscle that allows the passage of a swallowed bolus to the stomach and prevents the reflux of gastric contents into the oesophagus. The anatomical arrangement of the LOS includes semicircular clasp fibres adjacent to the lesser gastric curvature and sling fibres following the greater gastric curvature. Such anatomical arrangement together with an asymmetric intrinsic innervation and distinct proportion of neurotransmitters in both regions produces an asymmetric pressure profile. The LOS tone is myogenic in origin and depends on smooth muscle properties that lead to opening of L-type Ca(2+) channels; however it can be modulated by enteric motor neurons, the parasympathetic and sympathetic extrinsic nervous system and several neurohumoral substances. Nitric oxide synthesized by neuronal NOS is the main inhibitory neurotransmitter involved in LOS relaxation. Different putative neurotransmitters have been proposed to play a role together with NO. So far, only ATP or related purines have shown to be co-transmitters with NO. Acetylcholine and tachykinins are involved in the LOS contraction acting through acetylcholine M(3) and tachykinin NK(2) receptors. Nitric oxide can also be involved in the regulation of LOS contraction. The understanding of the mechanisms that originate and modulate LOS tone, relaxation and contraction and the characterization of neurotransmitters and receptors involved in LOS function are important to develop new pharmacological tools to treat primary oesophageal motor disorders and gastro-oesophageal reflux disease.

  7. Management practices and performance of mergers and acquisitions in Pakistan: mediating role of psychological contract.

    Science.gov (United States)

    Bari, Muhammad Waseem; Fanchen, Meng; Baloch, Muhammad Awais

    2016-01-01

    The objective of this study is to examine the direct and indirect effect of management practices (procedural justice, coordination approach, communication system, integration strategy, and coping programs) on merger and acquisition (M&A) performance in the Pakistan banking industry. Psychological contract (PC) acts as a mediator between Management practices and M&A performance. The Present study distributes a structured questionnaire to 700 bank employees of different management cadres. The useful response rate is 76 % (536 employees). It uses PLS-SEM technique for data analysis. (1) procedural justice is a key strategy which has highly significant direct and indirect effect on M&A performance; however integration strategy and the communication system have an only direct effect. (2) PC performs partial mediation at different levels between management practices and M&A financial and non-financial performance. This study provides an effective solution to solve the soft issues during and post-M&A process. This is one of the few studies which effectively integrate the five constructs into a single framework to study their effects on M&A performance. Limitations and future research directions are presented in the last section of the study.

  8. 48 CFR 970.5222-2 - Overtime management.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Overtime management. 970... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Solicitation Provisions and Contract Clauses for Management and Operating Contracts 970.5222-2 Overtime management. As prescribed in 970.2201-2-2...

  9. Harvest Regulations and Implementation Uncertainty in Small Game Harvest Management

    Directory of Open Access Journals (Sweden)

    Pål F. Moa

    2017-09-01

    Full Text Available A main challenge in harvest management is to set policies that maximize the probability that management goals are met. While the management cycle includes multiple sources of uncertainty, only some of these has received considerable attention. Currently, there is a large gap in our knowledge about implemention of harvest regulations, and to which extent indirect control methods such as harvest regulations are actually able to regulate harvest in accordance with intended management objectives. In this perspective article, we first summarize and discuss hunting regulations currently used in management of grouse species (Tetraonidae in Europe and North America. Management models suggested for grouse are most often based on proportional harvest or threshold harvest principles. These models are all built on theoretical principles for sustainable harvesting, and provide in the end an estimate on a total allowable catch. However, implementation uncertainty is rarely examined in empirical or theoretical harvest studies, and few general findings have been reported. Nevertheless, circumstantial evidence suggest that many of the most popular regulations are acting depensatory so that harvest bag sizes is more limited in years (or areas where game density is high, contrary to general recommendations. A better understanding of the implementation uncertainty related to harvest regulations is crucial in order to establish sustainable management systems. We suggest that scenario tools like Management System Evaluation (MSE should be more frequently used to examine robustness of currently applied harvest regulations to such implementation uncertainty until more empirical evidence is available.

  10. 77 FR 76938 - Defense Federal Acquisition Regulation Supplement: Contracting Activity Updates (DFARS Case 2012...

    Science.gov (United States)

    2012-12-31

    ... Security Cooperation Agency, the Defense Security Service, the Defense Threat Reduction Agency, the Missile... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 202 RIN 0750-AH81 Defense...: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Final rule. SUMMARY: DoD is...

  11. Nutrient management regulations in The Netherlands

    NARCIS (Netherlands)

    Schröder, J.J.; Neeteson, J.J.

    2008-01-01

    The application of nutrients affect the quality of the environment which justifies the consideration of regulations regarding their use in agriculture. In the early 1990s The Netherlands decided to use the indicator `nutrient surplus at farm level¿ as the basis for a regulation which was called the

  12. Change management of mergers: the impact on NHS staff and their psychological contracts.

    Science.gov (United States)

    Cortvriend, Penny

    2004-08-01

    The NHS has experienced a significant amount of organisational change and restructuring, which has included numerous mergers and de-mergers, since the Labour party came to power in the UK in 1997. However, to date there has been little in the way of evaluation of such changes, particularly the impact of organisational restructuring on the staff involved. This paper examines the human aspect of a merger, and subsequent de-merger, within a primary care trust (PCT) in the North of England, using a focus group methodology. The findings demonstrate that leadership and management styles have a significant impact on staff experiencing such changes. In addition, the psychological contract can be damaged due to the impact of several factors, inducing exit or intention to leave. Employees experienced a constant cycle of change with little time for stabilisation or adjustment, leading to negativity and lowered motivation at times.

  13. Managing Projects with the Public, -bringing Partnering, Contracts and Financing together in Building Public Services

    DEFF Research Database (Denmark)

    Koch, Christian

    2004-01-01

    of opportunity shows that on the operational level the contractual, financial and skill basis for the project has to be mobilized, negotiated, partly stabilized and renegotiated. The participating actors thus have to develop a new set of skills in dealing with municipalities and managing operations in PPPs....... of projects have had trouble to develop. The paper views PPP as an interaction between an emergent governance frame and operational activities in the project. PPP is an element of a networked public sector and the paper takes a network and political process approach to the shaping of PPP in Denmark....... It is analysed how the governance frame for these type of projects constituted a window of opportunity in the late nineties for “sale and lease back” arrangements, combined with partnering and more traditional design-build contracts. A case of a municipality renewing its school services, exploiting this window...

  14. Effect of Contract Research Organization Bureaucracy in Clinical Trial Management: A Model From Lung Cancer.

    Science.gov (United States)

    Gobbini, Elisa; Pilotto, Sara; Pasello, Giulia; Polo, Valentina; Di Maio, Massimo; Arizio, Francesca; Galetta, Domenico; Petrillo, Patrizia; Chiari, Rita; Matocci, Roberta; Di Costanzo, Alessandro; Di Stefano, Teresa Severina; Aglietta, Massimo; Cagnazzo, Celeste; Sperduti, Isabella; Bria, Emilio; Novello, Silvia

    2018-03-01

    Contract research organization (CRO) support is largely included in clinical trial management, although its effect in terms of time savings and benefit has not yet been quantified. We performed a retrospective multicenter analysis of lung cancer trials to explore differences in term of trial activation timelines and accrual for studies with and without CRO involvement. Results regarding study timelines from feasibility data to first patient enrollment were collected from 7 Italian thoracic oncology departments. The final accruals (screened/enrolled patients) are reported. We considered CRO/sponsor-administered and CRO-free trials according to who was responsible for the management of the crucial setup phases. Of 113 trials, 62 (54.9%) were CRO-administered, 34 (30.1%) were sponsor-administered, and 17 (15.0%) were CRO-free. The median time from feasibility invitation to documentation obtainment was 151 days in the CRO-administered trials versus 128 in the sponsor-administered and 120 in the CRO-free trials. The time from document submission to contract signature was 142 days in the CRO-administered versus 128 in the sponsor-administered and 132 in the CRO-free trials. The time from global accrual opening to first patient enrollment was 247 days for the CRO-administered versus 194 in the sponsor-administered and 151 in the CRO-free trials. No significant differences were observed in terms of the median overall timeline: 21 months in the CRO-administered, 15 in the sponsor-administered, and 18 months in the CRO-free studies (P = .29). Although no statistically significant differences were identified, the results of our analysis support the idea that bureaucratic procedures might require more time in CRO-administered trials than in sponsor-administered and CRO-free studies. This bureaucratic delay could negatively affect Italian patients' screening and enrollment compared with other countries. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Myofilament calcium sensitivity: Role in regulation of in vivo cardiac contraction and relaxation

    Directory of Open Access Journals (Sweden)

    Jae-Hoon Chung

    2016-12-01

    Full Text Available Myofilament calcium sensitivity is an often-used indicator of cardiac muscle function, often assessed in disease states such as hypertrophic cardiomyopathy (HCM and dilated cardiomyopathy (DCM. While calcium sensitivity measurement provides important insights into the mechanical force-generating capability of a muscle at steady-state, the dynamic behavior of the muscle cannot be sufficiently assessed with a force-pCa curve alone. The dissociation constant (Kd of the force-pCa curve depends on the ratio of the apparent on-rate (kon and apparent off-rate (koff of calcium on TnC and as a stand-alone parameter cannot provide an accurate depiction of the dynamic contraction and relaxation behavior without the additional quantification of kon or koff, or actually measuring dynamic twitch kinetics in an intact muscle. In this review, we examine the effect of length, frequency, and beta-adrenergic stimulation on myofilament calcium sensitivity and dynamic contraction, the effect of membrane permeabilization on calcium sensitivity, and the dynamic consequences of various myofilament protein mutations with potential implications in contractile and relaxation behavior.

  16. TVA nuclear power: Management of the nuclear program through personal services contracts

    International Nuclear Information System (INIS)

    1987-01-01

    Mr. Steven White, a retired admiral, is serving as manager of the TVA Office of Nuclear Power. GAO previously concluded that Mr. White's retention under contractual arrangements constituted the improper use of a personal services contract and represented a circumvention of the statutory ceiling on salary payments to TVA employees. This report finds that Mr. White's rate of pay is within the range of the salaries paid by a sample of nonfederal utilities to their top executives and is over two and a half times the average salary paid to executives who hold positions which appear to have responsibility for managing the utilities' power or nuclear power operations. GAO also found that (1) TVA's Office of Nuclear Power has employed an additional 25 persons since 1986 under arrangements similar to the employing arrangements of Mr. White and (2) TVA's Nuclear Safety Review staff no longer reports directly to the TVA Board of Directors and General Manager. It has relocated from Knoxville, Tennessee to Chattanooga, Tennessee

  17. FIDIC contracts: analysis of the impact of general and particular conditions on the financial risk management in Romanian infrastructure projects

    Directory of Open Access Journals (Sweden)

    Constanţa-Nicoleta Bodea

    2016-12-01

    Full Text Available Construction projects are characterized by risks and uncertainties mainly due to technical and economic complexity. Risk management is an important tool in making decisions involving the identification and reduction, avoidance or transfer risk and uncertainties consequences of events that occurs during project implementation. For this reason, the objective of the contract between the beneficiary and the contractor is the allocation of risk. The distribution of risk in contracts for the execution of construction works was and is an ongoing challenge faced by parties having a significant impact on the type of contract is used. On the one hand, the beneficiaries tend to transfer to the contractors as many of the project risks and uncertainties, on the other hand, the contractors look to exploit any weakness contract, so as to reduce their impact on the expected profit. One of the most important risks assumed by the contractor by signing the contract which is also increasingly common in the current economic situation is the reduced financial capacity to support the project. A purely legal or purely technical interpretation is not meant to describe the complexity of issues related to implementation of construction projects. For this reason the authors have adopted a multi-disciplinary approach, which includes the legal issues related to the nature of the contract, but also the financial and technical aspects of construction projects. The paper aims to analyze how special contract clauses can influence the implementation of construction projects and in particular the financial management of contractors. The authors propose a model for analyzing the impact of FIDIC contract conditions applied on a case study of five transport infrastructure projects.

  18. Managing urban wastewater in China: a survey of build-operate-transfer contracts

    NARCIS (Netherlands)

    Braadbaart, O.D.; Zhang, M.S.; Wang, Y.

    2009-01-01

    This paper reports on a nationwide field survey of wastewater plants under build-operate-transfer ( BOT) contracts in China. The survey yielded information on contracting parties, size, duration and location of 37 BOT contracts. The key findings are that municipal governments feature as first

  19. β-Arrestin regulation of myosin light chain phosphorylation promotes AT1aR-mediated cell contraction and migration.

    Directory of Open Access Journals (Sweden)

    Elie Simard

    Full Text Available Over the last decade, it has been established that G-protein-coupled receptors (GPCRs signal not only through canonical G-protein-mediated mechanisms, but also through the ubiquitous cellular scaffolds β-arrestin-1 and β-arrestin-2. Previous studies have implicated β-arrestins as regulators of actin reorganization in response to GPCR stimulation while also being required for membrane protrusion events that accompany cellular motility. One of the most critical events in the active movement of cells is the cyclic phosphorylation and activation of myosin light chain (MLC, which is required for cellular contraction and movement. We have identified the myosin light chain phosphatase Targeting Subunit (MYPT-1 as a binding partner of the β-arrestins and found that β-arrestins play a role in regulating the turnover of phosphorylated myosin light chain. In response to stimulation of the angiotensin Type 1a Receptor (AT1aR, MLC phosphorylation is induced quickly and potently. We have found that β-arrestin-2 facilitates dephosphorylation of MLC, while, in a reciprocal fashion, β-arrestin 1 limits dephosphorylation of MLC. Intriguingly, loss of either β-arrestin-1 or 2 blocks phospho-MLC turnover and causes a decrease in the contraction of cells as monitored by atomic force microscopy (AFM. Furthermore, by employing the β-arrestin biased ligand [Sar(1,Ile(4,Ile(8]-Ang, we demonstrate that AT1aR-mediated cellular motility involves a β-arrestin dependent component. This suggests that the reciprocal regulation of MLC phosphorylation status by β-arrestins-1 and 2 causes turnover in the phosphorylation status of MLC that is required for cell contractility and subsequent chemotaxic motility.

  20. 77 FR 43782 - Acquisition Regulations; Buy Indian Act; Procedures for Contracting

    Science.gov (United States)

    2012-07-26

    ... participation in the daily business management of the enterprise. Response: The proposed rule defines Indian... (iii) the management and daily business operations of an Indian economic enterprise must be controlled... percentage of Indian ownership of business enterprises from a mandatory 100 percent to minimum 51 percent. In...

  1. Catch-slip bonds can be dispensable for motor force regulation during skeletal muscle contraction

    Science.gov (United States)

    Dong, Chenling; Chen, Bin

    2015-07-01

    It is intriguing how multiple molecular motors can perform coordinated and synchronous functions, which is essential in various cellular processes. Recent studies on skeletal muscle might have shed light on this issue, where rather precise motor force regulation was partly attributed to the specific stochastic features of a single attached myosin motor. Though attached motors can randomly detach from actin filaments either through an adenosine triphosphate (ATP) hydrolysis cycle or through "catch-slip bond" breaking, their respective contribution in motor force regulation has not been clarified. Here, through simulating a mechanical model of sarcomere with a coupled Monte Carlo method and finite element method, we find that the stochastic features of an ATP hydrolysis cycle can be sufficient while those of catch-slip bonds can be dispensable for motor force regulation.

  2. Payment contracts in a preventive health care system: a perspective from operations management.

    Science.gov (United States)

    Yaesoubi, Reza; Roberts, Stephen D

    2011-12-01

    We consider a health care system consisting of two noncooperative parties: a health purchaser (payer) and a health provider, where the interaction between the two parties is governed by a payment contract. We determine the contracts that coordinate the health purchaser-health provider relationship; i.e. the contracts that maximize the population's welfare while allowing each entity to optimize its own objective function. We show that under certain conditions (1) when the number of customers for a preventive medical intervention is verifiable, there exists a gate-keeping contract and a set of concave piecewise linear contracts that coordinate the system, and (2) when the number of customers is not verifiable, there exists a contract of bounded linear form and a set of incentive-feasible concave piecewise linear contracts that coordinate the system. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. Management of Arrhythmias in Athletes: Atrial Fibrillation, Premature Ventricular Contractions, and Ventricular Tachycardia.

    Science.gov (United States)

    Lai, Ernest; Chung, Eugene H

    2017-10-09

    Management of atrial fibrillation, premature ventricular contractions, and ventricular tachycardia without underlying cardiac disease or arrhythmogenic conditions differs in athletes from the general population. Athletes tend to be younger, healthier individuals with few comorbidities. Therapies that work well in the general population may not be appropriate or preferable for athletes. Management strategies include deconditioning, pharmacologic therapy, such as rate control with β-blockers or non-dihydropyridine calcium channel blockers and rhythm control with class I or class III antiarrhythmic drugs, and catheter ablation. Deconditioning is not preferred by athletes because of lost playing time. Pharmacologic therapy is well tolerated among most individuals, but is not as favorable in athletes. Rate control medications can reduce performance and β-blockers, in particular, are prohibited in many sports. Antiarrhythmic drugs are preferred over rate control with athletes, but many, especially younger athletes, may not like the idea of long-term medical therapy. Catheter ablation has been proven to be safe and efficacious, may eliminate the need for long-term medical therapy, and is supported by the major societies (AHA, ACC, ESC).

  4. Maintenance and operations contractor plan for transition to the project Hanford management contract (PHMC)

    Energy Technology Data Exchange (ETDEWEB)

    Waite, J.L.

    1996-04-12

    This plan has been developed by Westinghouse Hanford Company (WHC), and its subcontractors ICF Kaiser Hanford (ICF KH) and BCS Richland, Inc. (BCSR), at the direction of the US Department of Energy (DOE), Richland Operations Office (RL). WHC and its subcontractors are hereafter referred to as the Maintenance and Operations (M and O) Contractor. The plan identifies actions involving the M and O Contractor that are critical to (1) prepare for a smooth transition to the Project Hanford Management Contractor (PHMC), and (2) support and assist the PHMC and RL in achieving transition as planned, with no or minimal impact to ongoing baseline activities. The plan is structured around two primary phases. The first is the pre-award phase, which started in mid-February 1996 and is currently scheduled to be completed on June 1, 1996, at which time the contract is currently planned to be awarded. The second is the follow-on four-month post-award phase from June 1, 1996, until October 1, 1996. Considering the magnitude and complexity of the scope of work being transitioned, completion in four months will require significant effort by all parties. To better ensure success, the M and O Contractor has developed a pre-award phase that is intended to maximize readiness for transition. Priority is given to preparation for facility assessments and processing of personnel, as these areas are determined to be on the critical path for transition. In addition, the M and O Contractor will put emphasis during the pre-award phase to close out open items prior to contract award, to include grievances, employee concerns, audit findings, compliance issues, etc.

  5. 77 FR 27547 - Federal Acquisition Regulation; Prohibition on Contracting With Inverted Domestic Corporations

    Science.gov (United States)

    2012-05-10

    ... concerns are unlikely to have been incorporated in the United States and then reincorporated in a tax haven... assess all costs and benefits of available regulatory alternatives and, if regulation is necessary, to select regulatory approaches that maximize net benefits (including potential economic, environmental...

  6. 77 FR 20598 - Defense Federal Acquisition Regulation Supplement: Solicitation Provisions and Contract Clauses...

    Science.gov (United States)

    2012-04-05

    ... commercial items, that includes the clause at 252.225-7001, Buy American Act and Balance of Payments Program... Acquisitions of Commercial Items AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD... acquisition of commercial items and to specify flowdown of clauses to commercial subcontracts. DATES: Comments...

  7. 78 FR 27968 - Federal Management Regulation; Redesignations of Federal Buildings

    Science.gov (United States)

    2013-05-13

    ... Management Regulation; Redesignations of Federal Buildings AGENCY: Public Buildings Service (PBS), General... designation and redesignation of six Federal buildings. DATES: Expiration Date: This bulletin announcement expires July 30, 2013. The building designations and redesignations remains in effect until canceled or...

  8. Virtual Leadership: The Influence of Transformational Leadership Style on Employee Satisfaction at the Defense Contract Management Agency

    Science.gov (United States)

    Johnson, Kevin A.

    2012-01-01

    The purpose of this quantitative correlational study was to examine the possible relationship between transformational leadership style behaviors and the influence it had on employee satisfaction. The information presented in this study involved virtual team members at the Defense Contract Management Agency, Navy Special Emphasis Operations. The…

  9. Suicide Prevention: Critical Elements for Managing Suicidal Clients and Counselor Liability Without the Use of a No-Suicide Contract

    Science.gov (United States)

    Lee, Jeane B.; Bartlett, Mary L.

    2005-01-01

    Despite its entrenchment as a standard of practice, no-suicide contracts fail to achieve their purpose as an effective part of treatment or as an effective method of inoculating counselors against potential lawsuits should a client commit suicide. Critical elements for managing suicidal clients and counselor liability without reliance on the…

  10. 48 CFR 1642.7001 - Management agreement.

    Science.gov (United States)

    2010-10-01

    ... EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Management Agreement (in Lieu of Novation Agreement) 1642.7001 Management agreement. When it is in the best interest of... day-to-day performance of the contract. Examples of situations in which a Management Agreement may be...

  11. 48 CFR 46.707 - Pricing aspects of fixed-price incentive contract warranties.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Pricing aspects of fixed-price incentive contract warranties. 46.707 Section 46.707 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 46.707 Pricing aspects of...

  12. Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle.

    Science.gov (United States)

    Zhuge, Ronghua; Bao, Rongfeng; Fogarty, Kevin E; Lifshitz, Lawrence M

    2010-01-15

    Ca2+ sparks are short lived and localized Ca2+ transients resulting from the opening of ryanodine receptors in sarcoplasmic reticulum. These events relax certain types of smooth muscle by activating big conductance Ca2+-activated K+ channels to produce spontaneous transient outward currents (STOCs) and the resultant closure of voltage-dependent Ca2+ channels. But in many smooth muscles from a variety of organs, Ca2+ sparks can additionally activate Ca2+-activated Cl(-) channels to generate spontaneous transient inward current (STICs). To date, the physiological roles of Ca2+ sparks in this latter group of smooth muscle remain elusive. Here, we show that in airway smooth muscle, Ca2+ sparks under physiological conditions, activating STOCs and STICs, induce biphasic membrane potential transients (BiMPTs), leading to membrane potential oscillations. Paradoxically, BiMPTs stabilize the membrane potential by clamping it within a negative range and prevent the generation of action potentials. Moreover, blocking either Ca2+ sparks or hyperpolarization components of BiMPTs activates voltage-dependent Ca2+ channels, resulting in an increase in global [Ca2+](i) and cell contraction. Therefore, Ca2+ sparks in smooth muscle presenting both STICs and STOCs act as a stabilizer of membrane potential, and altering the balance can profoundly alter the status of excitability and contractility. These results reveal a novel mechanism underlying the control of excitability and contractility in smooth muscle.

  13. 77 FR 12754 - Contractor Legal Management Requirements; Acquisition Regulations

    Science.gov (United States)

    2012-03-02

    ... DEPARTMENT OF ENERGY 10 CFR Part 719 48 Parts 931, 952 and 970 RIN 1990-AA37 Contractor Legal... rulemaking (NOPR) to revise existing regulations covering contractor legal management requirements and make... relating to the DOE notice of proposed rulemaking to revise existing regulations covering contractor legal...

  14. The management and regulation of decommissioning wastes

    International Nuclear Information System (INIS)

    Berkhout, F.

    1990-01-01

    Radioactive waste management is an inevitable consequence of nuclear technology. In the past it was often regarded as a peripheral matter, easily dealt with, and having little impact on the economics of the fuel cycle. Gradually, over the last two decades, waste management has asserted itself as one of nuclear power's most intractable problems. First, it is a problem of trying to understand through science the effects of discharging and disposing of man-made radioactivity to the general environment. Second, technologies for treating and disposing of the wastes, as well as techniques to verify their safety, must be developed. Third, and most problematically, a wide spread of public trust in the techniques of management must be nurtured. Disputes over each of these dimensions of the question exist in nearly all countries with nuclear programmes. Some of them may be near resolution, but many others are far from closure. Decommissioning, because it comes last in the nuclear life-cycle, is also the last important aspect of the technology to be considered seriously. In Britain, wastes arising from decommissioning, whether it is done slowly or quickly, are projected to have an important impact on the scale of radioactive waste management programmes, beginning in the mid-1990s. It follows that decommissioning, contentious in itself, is likely to exacerbate the difficulties of waste management. (author)

  15. 76 FR 23504 - Defense Federal Acquisition Regulation Supplement; Definition of Multiple-Award Contract (DFARS...

    Science.gov (United States)

    2011-04-27

    ... Order 13563 emphasizes the importance of quantifying both costs and benefits, of reducing costs, of..., was not subject to review under Section 6(b) of Executive Order 12866, Regulatory Planning and Review... collection requirements that require the approval of the Office of Management and Budget under the Paperwork...

  16. The current state of Contract Law in Australia and why it is important for rural managers to understand it

    OpenAIRE

    Smith, Tony

    2011-01-01

    Farmers are business managers and as such they must understand the law or they are likely to fall foul of it. This especially applies to contract law, with which they deal constantly. Contract law is made up of the common law – as the courts have decided it – and statute law- as the state and federal parliaments have enacted statutes which modify the common law. The most important and most recent of the latter is the new Australian Consumer Law.

  17. 41 CFR 301-53.5 - Are there exceptions to the mandatory use of contract city-pair fares and an agency's travel...

    Science.gov (United States)

    2010-07-01

    ... the mandatory use of contract city-pair fares and an agency's travel management service? 301-53.5 Section 301-53.5 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY... the mandatory use of contract city-pair fares and an agency's travel management service? Yes, the...

  18. The evolution of electricity prices in an uncertain world. Contracting and managing the price risk

    International Nuclear Information System (INIS)

    Vassilopoulos, Ph.; Rapin, D.

    2004-01-01

    With the liberalization of the electricity market, the large industrial consumers saw their electric bill changing nature. Before, this price reflected a long term negotiation with the monopoly, now it is established in a free way via wholesale markets. This evolution marks a transfer of the management of price risk from the producer towards the consumer. This change is not in itself a problem if the hedging instruments are adapted. We note a contamination of the price of the derivative products by the spot while at the same time the traditional relation between cash and term is not always valid for electricity because of its non storability. When well even the price of the derivative products would be formed in an autonomous way, it poses a second problem: that of their indexing on price references like Platt's whose result is assimilated more to a survey of large producers than a true confrontation of supply and demand. This article proposes to examine this change of nature and behaviour of electricity prices. After having explained the intrinsically volatile characteristic of spot prices, we will recall that the products in the long term are not always optimal solutions to decrease this price risk. Lastly, we will highlight a solution of skirting at the risks mentioned above: contracting between producers and consumers. (authors)

  19. Transitioning from operations to environmental restoration: Startup of the Fernald Environmental Restoration Management Contract

    International Nuclear Information System (INIS)

    Little, C.C.; Kozlowski, D.R.

    1993-10-01

    This paper will present a description of the program undertaken by the Fernald Environmental Restoration Management Contractor (ERMC) to effect a transition from operation of the Fernald site by the past M ampersand O contractor, WEMCO, to DOE's new mission and contractual approach focussed on site remediation. This transition, on a first of its kind contract, represented a significant, proactive approach on the part of DOE to pursue the clean up of its weapon's production facilities in a faster, more cost-effective manner. The paper will discuss the formal transition readiness review process and the lessons teamed by DOE and the contractor during transition. The oral presentation will be shared by both authors with one half of the time allocated to the transition readiness demonstration process and one half to the lessons learned. The objective of having a Department of Energy (DOE) Headquarters representative participate in the transition to the first ERMC was to develop a handbook to assist other sites proceeding with the ERMC concept, such as the Richland Operations Office, and to develop a lessons learned document. Because a lessons learned report is available separately, only those more significant lessons learned are highlighted in this paper

  20. Commitments of Psychological Contracts and Diagnostic Use of Management Control Systems

    Directory of Open Access Journals (Sweden)

    Ivan Canan

    2016-06-01

    Full Text Available Investigating the commitments the Surveillance Agents from the National Telecommunications Agency (Anatel made in their psychological contracts and the diagnostic use of the management control system of the entity, this study tested the hypothesis that individuals tend to be more committed to aspects they are charged for within organizations. This is a theoretical and empirical study that assumed that the commitments comprise the part of the belief that individuals develop on reciprocal relations of exchange between themselves and their contractors, in line with the model by Rousseau (1989; 1995. It was also assumed that the extent to which aspects are charged from the members of an organization matches their perception of the diagnostic use of formal and informal control systems. Methodologically, the research was developed in two phases, the first qualitative, involving documentary analysis and content analysis of organizational documents; and the second quantitative, with the application of questionnaires answered by individuals who occupy the individual position referred to in the organization, who evaluated behavioral parameters that act on them and that were identified in the first phase. The data showed that 42 respondents tend to maintain high levels of commitment to the rules and standards proposed for their function. Statistical results also suggest that there is a significant positive correlation between the commitments assumed and the perceived diagnostic use of control systems for the surveillance agents who answered the questionnaire.

  1. The many outcomes from contracting out: The voice of public managers

    DEFF Research Database (Denmark)

    Lindholst, Andrej Christian; Hansen, Morten Balle; Randrup, Thomas Barfoed

    2018-01-01

    perspective is summarised in a best-case, worst-case and complex-case scenario highlighting the mix, complexities and trade-offs in a composite set of contracting outcomes. The nature of contracting outcomes as complex and composite rather than unidimensional is one key finding. Furthermore, the importance...

  2. Role of Active Contraction and Tropomodulins in Regulating Actin Filament Length and Sarcomere Structure in Developing Zebrafish Skeletal Muscle.

    Science.gov (United States)

    Mazelet, Lise; Parker, Matthew O; Li, Mei; Arner, Anders; Ashworth, Rachel

    2016-01-01

    Whilst it is recognized that contraction plays an important part in maintaining the structure and function of mature skeletal muscle, its role during development remains undefined. In this study the role of movement in skeletal muscle maturation was investigated in intact zebrafish embryos using a combination of genetic and pharmacological approaches. An immotile mutant line (cacnb1 (ts25) ) which lacks functional voltage-gated calcium channels (dihydropyridine receptors) in the muscle and pharmacological immobilization of embryos with a reversible anesthetic (Tricaine), allowed the study of paralysis (in mutants and anesthetized fish) and recovery of movement (reversal of anesthetic treatment). The effect of paralysis in early embryos (aged between 17 and 24 hours post-fertilization, hpf) on skeletal muscle structure at both myofibrillar and myofilament level was determined using both immunostaining with confocal microscopy and small angle X-ray diffraction. The consequences of paralysis and subsequent recovery on the localization of the actin capping proteins Tropomodulin 1 & 4 (Tmod) in fish aged from 17 hpf until 42 hpf was also assessed. The functional consequences of early paralysis were investigated by examining the mechanical properties of the larval muscle. The length-force relationship, active and passive tension, was measured in immotile, recovered and control skeletal muscle at 5 and 7 day post-fertilization (dpf). Recovery of muscle function was also assessed by examining swimming patterns in recovered and control fish. Inhibition of the initial embryonic movements (up to 24 hpf) resulted in an increase in myofibril length and a decrease in width followed by almost complete recovery in both moving and paralyzed fish by 42 hpf. In conclusion, myofibril organization is regulated by a dual mechanism involving movement-dependent and movement-independent processes. The initial contractile event itself drives the localization of Tmod1 to its sarcomeric

  3. Role of active contraction and tropomodulins in regulating actin filament length and sarcomere structure in developing zebrafish skeletal muscle

    Directory of Open Access Journals (Sweden)

    Lise eMazelet

    2016-03-01

    Full Text Available Whilst it is recognised that contraction plays an important part in maintaining the structure and function of mature skeletal muscle, its role during development remains undefined. In this study the role of movement in skeletal muscle maturation was investigated in intact zebrafish embryos using a combination of genetic and pharmacological approaches. An immotile mutant line (cacnb1ts25 which lacks functional voltage-gated calcium channels (dihydropyridine receptors in the muscle and pharmacological immobilisation of embryos with a reversible anaesthetic (Tricaine, allowed the study of paralysis (in mutants and anaesthetised fish and recovery of movement (reversal of anaesthetic treatment. The effect of paralysis in early embryos (aged between 17-24 hours post fertilisation, hpf on skeletal muscle structure at both myofibrillar and myofilament level was determined using both immunostaining with confocal microscopy and small angle X-ray diffraction. The consequences of paralysis and subsequent recovery on the localisation of the actin capping proteins Tropomodulin 1 &4 (Tmod in fish aged from 17hpf until 42hpf was also assessed. The functional consequences of early paralysis were investigated by examining the mechanical properties of the larval muscle. The length-force relationship, active and passive tension, was measured in immotile, recovered and control skeletal muscle at 5 and 7 day post fertilisation (dpf. Recovery of muscle function was also assessed by examining swimming patterns in recovered and control fish. Inhibition of the initial embryonic movements (up to 24 hpf resulted in an increase in myofibril length and a decrease in width followed by almost complete recovery in both moving and paralysed fish by 42hpf. In conclusion, myofibril organisation is regulated by a dual mechanism involving movement-dependent and movement-independent processes. The initial contractile event itself drives the localisation of Tmod1 to its sarcomeric

  4. 48 CFR 1316.406 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 1316.406 Section 1316.406 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 1316.406 Contract clauses. Insert a clause...

  5. 48 CFR 716.406 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 716.406 Section 716.406 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Cost Reimbursement Contracts 716.406 Contract clauses. The...

  6. 48 CFR 916.307 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 916.307 Section 916.307 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Cost-Reimbursement Contracts 916.307 Contract clauses. (g) Insert the...

  7. 76 FR 44884 - Federal Acquisition Regulation; Payments Under Time-and-Materials and Labor-Hour Contracts

    Science.gov (United States)

    2011-07-27

    ... under revised Alternate I. (b) Completion Voucher. The Allowable Cost and Payment, FAR clause 52.216-7.... * * * * * Payments Under Time-and-Material and Labor-Hour Contracts (Date) * * * * * (a) * * * (5) Vouchers may be... final payment under this contract, the Contracting Officer may request audit of the vouchers and...

  8. Tank Operations Contract Construction Management Methodology. Utilizing The Agency Method Of Construction Management To Safely And Effectively Complete Nuclear Construction Work

    International Nuclear Information System (INIS)

    Leso, K.F.; Hamilton, H.M.; Farner, M.; Heath, T.

    2010-01-01

    Washington River Protection Solutions, LLC (WRPS) has faced significant project management challenges in managing Davis-Bacon construction work that meets contractually required small business goals. The unique challenge is to provide contracting opportunities to multiple small business construction subcontractors while performing high hazard work in a safe and productive manner. Previous to the Washington River Protection Solutions, LLC contract, Construction work at the Hanford Tank Farms was contracted to large companies, while current Department of Energy (DOE) Contracts typically emphasize small business awards. As an integral part of Nuclear Project Management at Hanford Tank Farms, construction involves removal of old equipment and structures and installation of new infrastructure to support waste retrieval and waste feed delivery to the Waste Treatment Plant. Utilizing the optimum construction approach ensures that the contractors responsible for this work are successful in meeting safety, quality, cost and schedule objectives while working in a very hazardous environment. This paper describes the successful transition from a traditional project delivery method that utilized a large business general contractor and subcontractors to a new project construction management model that is more oriented to small businesses. Construction has selected the Agency Construction Management Method. This method was implemented in the first quarter of Fiscal Year (FY) 2009, where Construction Management is performed by substantially home office resources from the URS Northwest Office in Richland, Washington. The Agency Method has allowed WRPS to provide proven Construction Managers and Field Leads to mentor and direct small business contractors, thus providing expertise and assurance of a successful project. Construction execution contracts are subcontracted directly by WRPS to small or disadvantaged contractors that are mentored and supported by DRS personnel. Each small

  9. TANK OPERATIONS CONTRACT CONSTRUCTION MANAGEMENT METHODOLOGY UTILIZING THE AGENCY METHOD OF CONSTRUCTION MANAGEMENT TO SAFELY AND EFFECTIVELY COMPLETE NUCLEAR CONSTRUCTION WORK

    Energy Technology Data Exchange (ETDEWEB)

    LESO KF; HAMILTON HM; FARNER M; HEATH T

    2010-01-14

    Washington River Protection Solutions, LLC (WRPS) has faced significant project management challenges in managing Davis-Bacon construction work that meets contractually required small business goals. The unique challenge is to provide contracting opportunities to multiple small business construction subcontractors while performing high hazard work in a safe and productive manner. Previous to the Washington River Protection Solutions, LLC contract, Construction work at the Hanford Tank Farms was contracted to large companies, while current Department of Energy (DOE) Contracts typically emphasize small business awards. As an integral part of Nuclear Project Management at Hanford Tank Farms, construction involves removal of old equipment and structures and installation of new infrastructure to support waste retrieval and waste feed delivery to the Waste Treatment Plant. Utilizing the optimum construction approach ensures that the contractors responsible for this work are successful in meeting safety, quality, cost and schedule objectives while working in a very hazardous environment. This paper describes the successful transition from a traditional project delivery method that utilized a large business general contractor and subcontractors to a new project construction management model that is more oriented to small businesses. Construction has selected the Agency Construction Management Method. This method was implemented in the first quarter of Fiscal Year (FY) 2009, where Construction Management is performed by substantially home office resources from the URS Northwest Office in Richland, Washington. The Agency Method has allowed WRPS to provide proven Construction Managers and Field Leads to mentor and direct small business contractors, thus providing expertise and assurance of a successful project. Construction execution contracts are subcontracted directly by WRPS to small or disadvantaged contractors that are mentored and supported by DRS personnel. Each small

  10. 48 CFR 937.7040 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 937.7040... CONTRACTING SERVICE CONTRACTING Protective Services Contracting 937.7040 Contract clauses. The contracting... services” in all protective services solicitations and contracts involving DOE-owned facilities requiring...

  11. 48 CFR 47.104-3 - Cost-reimbursement contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cost-reimbursement... CONTRACT MANAGEMENT TRANSPORTATION General 47.104-3 Cost-reimbursement contracts. (a) 49 U.S.C. 10721 and... accrues to the Government, i.e., the Government shall pay the charges or directly and completely reimburse...

  12. Professional services contract manager development and certification strategy : spr 696 : final report.

    Science.gov (United States)

    2013-02-27

    SCDOT hires many consultants to provide professional services in support of its planning, design, construction and : maintenance projects. SCDOT personnel responsible for procuring and administering these professional service : contracts, especially ...

  13. Managing hydroclimatological risk to water supply with option contracts and reservoir index insurance

    Science.gov (United States)

    Brown, Casey; Carriquiry, Miguel

    2007-11-01

    This paper explores the performance of a system of economic instruments designed to facilitate the reduction of hydroclimatologic variability-induced impacts on stakeholders of shared water supply. The system is composed of bulk water option contracts between urban water suppliers and agricultural users and insurance indexed on reservoir inflows. The insurance is designed to cover the financial needs of the water supplier in situations where the option is likely to be exercised. Insurance provides the irregularly needed funds for exercising the water options. The combined option contract - reservoir index insurance system creates risk sharing between sectors that is currently lacking in many shared water situations. Contracts are designed for a shared agriculture - urban water system in Metro Manila, Philippines, using optimization and Monte Carlo analysis. Observed reservoir inflows are used to simulate contract performance. Results indicate the option - insurance design effectively smooths water supply costs of hydrologic variability for both agriculture and urban water.

  14. Cannabinoid signalling inhibits sarcoplasmic Ca2+ release and regulates excitation–contraction coupling in mammalian skeletal muscle

    Science.gov (United States)

    Oláh, Tamás; Bodnár, Dóra; Tóth, Adrienn; Vincze, János; Fodor, János; Reischl, Barbara; Kovács, Adrienn; Ruzsnavszky, Olga; Dienes, Beatrix; Szentesi, Péter; Friedrich, Oliver

    2016-01-01

    Key points Marijuana was found to cause muscle weakness, although the exact regulatory role of its receptors (CB1 cannabinoid receptor; CB1R) in the excitation–contraction coupling (ECC) of mammalian skeletal muscle remains unknown.We found that CB1R activation or its knockout did not affect muscle force directly, whereas its activation decreased the Ca2+‐sensitivity of the contractile apparatus and made the muscle fibres more prone to fatigue.We demonstrate that CB1Rs are not connected to the inositol 1,4,5‐trisphosphate pathway either in myotubes or in adult muscle fibres.By contrast, CB1Rs constitutively inhibit sarcoplasmic Ca2+ release and sarcoplasmic reticulum Ca2+ ATPase during ECC in a Gi/o protein‐mediated way in adult skeletal muscle fibres but not in myotubes.These results help with our understanding of the physiological effects and pathological consequences of CB1R activation in skeletal muscle and may be useful in the development of new cannabinoid drugs. Abstract Marijuana was found to cause muscle weakness, although it is unknown whether it affects the muscles directly or modulates only the motor control of the central nervous system. Although the presence of CB1 cannabinoid receptors (CB1R), which are responsible for the psychoactive effects of the drug in the brain, have recently been demonstrated in skeletal muscle, it is unclear how CB1R‐mediated signalling affects the contraction and Ca²⁺ homeostasis of mammalian skeletal muscle. In the present study, we demonstrate that in vitro CB1R activation increased muscle fatigability and decreased the Ca2+‐sensitivity of the contractile apparatus, whereas it did not alter the amplitude of single twitch contractions. In myotubes, CB1R agonists neither evoked, nor influenced inositol 1,4,5‐trisphosphate (IP3)‐mediated Ca2+ transients, nor did they alter excitation–contraction coupling. By contrast, in isolated muscle fibres of wild‐type mice, although CB1R agonists did not evoke IP3

  15. Cannabinoid signalling inhibits sarcoplasmic Ca2+ release and regulates excitation-contraction coupling in mammalian skeletal muscle.

    Science.gov (United States)

    Oláh, Tamás; Bodnár, Dóra; Tóth, Adrienn; Vincze, János; Fodor, János; Reischl, Barbara; Kovács, Adrienn; Ruzsnavszky, Olga; Dienes, Beatrix; Szentesi, Péter; Friedrich, Oliver; Csernoch, László

    2016-12-15

    Marijuana was found to cause muscle weakness, although the exact regulatory role of its receptors (CB1 cannabinoid receptor; CB1R) in the excitation-contraction coupling (ECC) of mammalian skeletal muscle remains unknown. We found that CB1R activation or its knockout did not affect muscle force directly, whereas its activation decreased the Ca 2+ -sensitivity of the contractile apparatus and made the muscle fibres more prone to fatigue. We demonstrate that CB1Rs are not connected to the inositol 1,4,5-trisphosphate pathway either in myotubes or in adult muscle fibres. By contrast, CB1Rs constitutively inhibit sarcoplasmic Ca 2+ release and sarcoplasmic reticulum Ca 2+ ATPase during ECC in a G i/o protein-mediated way in adult skeletal muscle fibres but not in myotubes. These results help with our understanding of the physiological effects and pathological consequences of CB1R activation in skeletal muscle and may be useful in the development of new cannabinoid drugs. Marijuana was found to cause muscle weakness, although it is unknown whether it affects the muscles directly or modulates only the motor control of the central nervous system. Although the presence of CB1 cannabinoid receptors (CB1R), which are responsible for the psychoactive effects of the drug in the brain, have recently been demonstrated in skeletal muscle, it is unclear how CB1R-mediated signalling affects the contraction and Ca²⁺ homeostasis of mammalian skeletal muscle. In the present study, we demonstrate that in vitro CB1R activation increased muscle fatigability and decreased the Ca 2+ -sensitivity of the contractile apparatus, whereas it did not alter the amplitude of single twitch contractions. In myotubes, CB1R agonists neither evoked, nor influenced inositol 1,4,5-trisphosphate (IP 3 )-mediated Ca 2+ transients, nor did they alter excitation-contraction coupling. By contrast, in isolated muscle fibres of wild-type mice, although CB1R agonists did not evoke IP 3 -mediated Ca 2

  16. 48 CFR 970.2201-2 - Overtime management.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Overtime management. 970... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Application of Labor Policies 970.2201-2 Overtime management. ...

  17. 48 CFR 970.0370 - Management Controls and Improvements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Management Controls and... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Improper Business Practices and Personal Conflicts of Interest 970.0370 Management Controls and Improvements. ...

  18. The effect of manure management regulations on competitiveness

    DEFF Research Database (Denmark)

    Andersen, Mikael Skou

    2003-01-01

    Significant differences in the competitiveness of pig production along with growing international competition in the pigmeat market have raised concerns about the cost impact of environmental regulations on producers, particularly those regarding the management of manure. There appears to be a U...

  19. Store-Assistance Management for a Supply Chain with Consumer Return under Consignment Contract

    Directory of Open Access Journals (Sweden)

    Zhihui Wu

    2017-01-01

    Full Text Available In this paper, the strategy problems of pricing and store-assistance service investment are investigated for a supply chain with consumer return, where the considered supply chain under consignment contract consists of a single manufacturer and a single retailer. Firstly, we use differential equation to model the evolution of store-assistance service level and depict the effect of store-assistance service level on the return rate. By applying two-stage game, both optimal pricing and store-assistance service strategies are obtained based on the presented optimal control model. Subsequently, the committed dynamic consignment price contract is designed to coordinate and improve the performance of supply chain. Finally, a numerical example is provided to illustrate the impacts of the effectiveness of store-assistance service level and decay rate on the feasible region of corresponding contract.

  20. Cogeneration new electric power purchase contract. What is the impact of the new regulation framework approved in december 2002

    International Nuclear Information System (INIS)

    Loffler, P.; Guenaire, M.; Balaguier, Ph.; Haushalter, J.; Fraisse, J.L.; Bernard, L.; Gauthier, J.M.; Tronche, D.; Ravetto, P.

    2003-06-01

    This conference deals with the following topics: the new legal framework and the future contracts evolution, is it possible and interesting to take advantage of the new purchase contract, energy efficiency and technical innovation, the problems of the electric power network integration, the organization of a cogeneration project, experiences examples. (A.L.B.)

  1. 77 FR 194 - Federal Acquisition Regulation; Time-and-Materials and Labor-Hour Contracts for Commercial Items

    Science.gov (United States)

    2012-01-03

    ..., or a cost-plus term. Otherwise, the respondent thinks contracting officers are likely to read the... target cost), or both. Unless otherwise specified in the contract, the ceiling price or target price is... not possible to accurately estimate the extent or duration of the work or anticipated costs with any...

  2. Concept of contracting authority

    OpenAIRE

    Kasiliauskaitė, Vitalija

    2016-01-01

    Concept of Contracting Authority Law on Public Procurement the procurement concept implies the conclusion that public procurement be declared only such purchases are carried out by the contracting authority. The contracting authorities can be a subject of state and municipal management institutes, whose assignment authority is determined by a functional approach. Also, contracting authorities may be public and legal entities, but that the public interest and operates non-commercial activities...

  3. Management Control of Market Transactions: The Relation Between Transaction Characteristics, Incomplete Contract Design and Subsequent Performance

    NARCIS (Netherlands)

    Anderson, S.W.; Dekker, H.C.

    2005-01-01

    Using an unusually comprehensive database on 858 transactions for information technology products and accompanying services, we study how close partners who are exposed to opportunistic hazards structure and control a significant transaction. We analyze data on the terms of contracting to determine

  4. Understanding micro-processes of institutionalization: stewardship contracting and national forest management

    Science.gov (United States)

    Cassandra Moseley; Susan Charnley

    2014-01-01

    This paper examines micro-processes of institutionalization, using the case of stewardship contracting within the US Forest Service. Our basic premise is that, until a new policy becomes an everyday practice among local actors, it will not become institutionalized at the macro-scale. We find that micro-processes of institutionalization are driven by a mixture of large-...

  5. 48 CFR 732.111 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 732.111... CONTRACTING REQUIREMENTS CONTRACT FINANCING General 732.111 Contract clauses. (a) [Reserved] (b) USAID may... Agency-specific indefinite quantity contracts that are a combination of contract types. Rather than using...

  6. Muscle Contraction.

    Science.gov (United States)

    Sweeney, H Lee; Hammers, David W

    2018-02-01

    SUMMARYMuscle cells are designed to generate force and movement. There are three types of mammalian muscles-skeletal, cardiac, and smooth. Skeletal muscles are attached to bones and move them relative to each other. Cardiac muscle comprises the heart, which pumps blood through the vasculature. Skeletal and cardiac muscles are known as striated muscles, because the filaments of actin and myosin that power their contraction are organized into repeating arrays, called sarcomeres, that have a striated microscopic appearance. Smooth muscle does not contain sarcomeres but uses the contraction of filaments of actin and myosin to constrict blood vessels and move the contents of hollow organs in the body. Here, we review the principal molecular organization of the three types of muscle and their contractile regulation through signaling mechanisms and discuss their major structural and functional similarities that hint at the possible evolutionary relationships between the cell types. Copyright © 2018 Cold Spring Harbor Laboratory Press; all rights reserved.

  7. Nuclear Regulator Knowledge Management in a Dynamic Nuclear Industry Environment

    International Nuclear Information System (INIS)

    Turner, J.

    2016-01-01

    Full text: The paper outlines the experiences to date in developing mature knowledge management within the UK’s nuclear regulatory body The Office for Nuclear Regulation (ONR). In 2010 concerns over the loss of knowledge due to the age profile within the organization instigated a review of knowledge management and the development of a knowledge management initiative. Initially activities focused on knowledge capture but in order to move to through life knowledge transfer, knowledge management was then aligned with organizational resilience initiatives. A review of progress highlighted the need to better engage the whole organization to achieve the desired level of maturity for knowledge management. Knowledge management activities now cover organizational culture and environment and all aspects of organizational resilience. Benefits to date include clear understanding of core knowledge requirements, better specifications for recruitment and training and the ability to deploy new regulatory approaches. During the period of implementing the knowledge management programme ONR undertook several organizational changes in moving to become a separate statutory body. The UK nuclear industry was in a period of increased activity including the planning of new nuclear reactors. This dynamic environment caused challenges for embedding knowledge management within ONR which are discussed in the paper. (author

  8. Networks and informal contract law

    NARCIS (Netherlands)

    Tjong Tjin Tai, Eric; Brownsword, Roger; van Gestel, Rob A.J.; Micklitz, Hans-W.

    2017-01-01

    It is often argued that formal contract law cannot treat networks correctly. An analysis of networks in an informal contract law system shows that informal contract law is no panacea. Remaining problems require a different approach to legal regulation and contract practice.

  9. Are Management-Based Regulations Effective? Evidence from State Pollution Prevention Programs

    Science.gov (United States)

    Bennear, Lori Snyder

    2007-01-01

    This paper evaluates a recent innovation in regulating risk called management-based regulation. Traditionally, risk regulation has either specified a particular means of achieving a risk-reduction goal or specified the goal and left the means of achieving that goal up to the regulated entity. In contrast, management-based regulation neither…

  10. PROJECT HANFORD MANAGEMENT CONTRACT (PHMC) PERFORMANCE REPORT 05/2004 (WWW.HANFORD.GOV/EMPR.INDEX.CFM)

    International Nuclear Information System (INIS)

    PIELSTICK, R.M.

    2004-01-01

    This report is the monthly performance summary of the Central Plateau Contractors. FH work scope responsibilities are described, and other contractor/RL-managed work is excluded. Section A, Overview, provides a summary of the cost, schedule, and technical performance described in this report. It summarizes performance for the period covered, highlights areas worthy of management attention, and provides key performance activities as extracted from the contractor baseline. Subsequent sections of this report provide detailed performance data relative to contract sections (e.g., Project Hanford Cleanup Work Summary, Waste and Spent Nuclear Fuel Management Operations, Infrastructure and Hanford Site Services, and other Work Scope). All information is as of the end of May 2004 unless otherwise noted

  11. An Agile Enterprise Regulation Architecture for Health Information Security Management

    Science.gov (United States)

    Chen, Ying-Pei; Hsieh, Sung-Huai; Chien, Tsan-Nan; Chen, Heng-Shuen; Luh, Jer-Junn; Lai, Jin-Shin; Lai, Feipei; Chen, Sao-Jie

    2010-01-01

    Abstract Information security management for healthcare enterprises is complex as well as mission critical. Information technology requests from clinical users are of such urgency that the information office should do its best to achieve as many user requests as possible at a high service level using swift security policies. This research proposes the Agile Enterprise Regulation Architecture (AERA) of information security management for healthcare enterprises to implement as part of the electronic health record process. Survey outcomes and evidential experiences from a sample of medical center users proved that AERA encourages the information officials and enterprise administrators to overcome the challenges faced within an electronically equipped hospital. PMID:20815748

  12. An agile enterprise regulation architecture for health information security management.

    Science.gov (United States)

    Chen, Ying-Pei; Hsieh, Sung-Huai; Cheng, Po-Hsun; Chien, Tsan-Nan; Chen, Heng-Shuen; Luh, Jer-Junn; Lai, Jin-Shin; Lai, Feipei; Chen, Sao-Jie

    2010-09-01

    Information security management for healthcare enterprises is complex as well as mission critical. Information technology requests from clinical users are of such urgency that the information office should do its best to achieve as many user requests as possible at a high service level using swift security policies. This research proposes the Agile Enterprise Regulation Architecture (AERA) of information security management for healthcare enterprises to implement as part of the electronic health record process. Survey outcomes and evidential experiences from a sample of medical center users proved that AERA encourages the information officials and enterprise administrators to overcome the challenges faced within an electronically equipped hospital.

  13. 76 FR 8303 - Defense Federal Acquisition Regulation Supplement; Award-Fee Contracts (DFARS Case 2006-D021)

    Science.gov (United States)

    2011-02-14

    ... event a contractor fails to meet contractual obligations. Assuming the contract is properly structured... meet contractual performance requirements will maximize the amount of award fee earned, there is no...

  14. [Problems of safety regulation under radioactive waste management in Russia].

    Science.gov (United States)

    Monastyrskaia, S G; Kochetkov, O A; Barchukov, V G; Kuznetsova, L I

    2012-01-01

    Analysis of the requirements of Federal Law N 190 "About radioactive waste management and incorporation of changes into some legislative acts of the Russian Federation", as well as normative-legislative documents actual and planned to be published related to provision of radiation protection of the workers and the public have been done. Problems of safety regulation raised due to different approaches of Rospotrebnadzor, FMBA of Russia, Rostekhnadzor and Minprirody with respect to classification and categorization of the radioactive wastes, disposal, exemption from regulatory control, etc. have been discussed in the paper. Proposals regarding improvement of the system of safety regulation under radioactive waste management and of cooperation of various regulatory bodies have been formulated.

  15. Managing wind turbine reliability and maintenance via performance-based contract

    DEFF Research Database (Denmark)

    Jin, Tongdan; Ding, Yi; Guo, Huairui

    2012-01-01

    between system cost, reliability and spare parts stocking. This analytical insight into the system performance allows the turbine manufacturer to optimize design, production, and after-sales services. The study aims to create a theoretical basis to facilitate the transition of the maintenance paradigm......Performance-based contracting (PBC) is reshaping the acquisition, operation, and maintenance of capital equipment. Under the PBC scheme, we propose a holistic approach for lowering the cost of wind turbine ownership while meeting the availability requirement. Our effects are focused on integrated...... firms who design and market wind turbines, and also provide maintenance and repair service. PBC differs from conventional service contracts in that the wind farmers compensate the service provider for the system performance, not the spare parts and repair labor. We explore the analytical relationship...

  16. Characteristics of nuclear contracts. Pt. 1

    International Nuclear Information System (INIS)

    Blanchard, R.

    1976-01-01

    While the object of nuclear contracts is specific, these contracts are concluded according to proven techniques based on general regulations on contracts. Following a review of contract classification, they are differentiated according to the nature of the co-contracting parties, the purpose of the contract itself, the procedure for drawing up the contracts, and payment. The operations prior to the contract vary in that they may include a call for tenders, an option for delays or a letter of intent. (NEA) [fr

  17. A Classification and Analysis of National Contract Management Journal Articles from 1966 Through 1989

    Science.gov (United States)

    1991-06-01

    author examined profitability in terms of the Capital Asset Pricing Model ( CAPM ) . This is a model designed by investment analysts to determine required...weapon systems are substituted for assets . The authors first examine the limitations of constrained optimization models , then describe the Portfolio...contracts. Other sections discuss warranty definition, approval, limitations on use, preparation, pricing aspects, and technical data. The new clauses are

  18. Formation of modern theoretical regulations about organization concerning management development

    Directory of Open Access Journals (Sweden)

    Zhalinska I.V.

    2017-03-01

    Full Text Available The article deals with the scientific concepts about an organization as the entity of management concerning management development. The author studies the principal theoretical regulations about an organization within the most spread schools of management and context of development of other managerial concepts in particular, strategic management. It is found out that an organization and its development had not considered as the factor of an effective activity before. Researches paid their attention to single aspects of organization activity where the aspects allowed to increase economic efficiency. However, the objective complication of conditions of enterprises’ activities caused the necessity of scientific research of adequate models of functioning and development of organizations, which currently cannot be provided by traditional management concepts. Thus, theoretical and practical prerequisites arise for a separate scientific set of researches within the science of management such as the theory of an organization. The article describes the main classified approaches to the models of an organization. The paper researches the challenges in present management, and those ones, which have caused the crisis in modern management. It is singled out the following actual aspects of modern organizational processes as the all-round use of modern information and computer systems, the development of integration and in cooperation in management, the appearance of new management technologies, the use of new assessment criteria for organization activity, striving for organizational shifts and innovations. Due to the generalization of the study results, the authors single out such key aspects in the development of the science of management, as the crisis of traditional management influences upon practical activity of modern organizations; the achievements of traditional management schools are becoming necessary, but not determinant factors of organization

  19. 48 CFR 19.808 - Contract negotiation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract negotiation. 19.808 Section 19.808 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC....808 Contract negotiation. ...

  20. Banking contracts

    OpenAIRE

    Durčáková, Klára

    2010-01-01

    Resumé - Bank Contracts Bank Contracts are an integral part of our everyday lives. Citizen and bussines entities used bank contracts very often. Despite this fact we can't find legal definition in the Czech law. Banking contracts understand contracts that are signed by banks in their business activities and obligations under these contracts arise. While the banking contracts have been widely used, in Czech law there is not too much literature and judgements abou this issue. Lack of legislatio...

  1. 41 CFR 102-193.10 - What are the goals of the Federal Records Management Program?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are the goals of the Federal Records Management Program? 102-193.10 Section 102-193.10 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION...

  2. The Secret to Legal Foretelling: Generic and Inter-Generic Aspects of Vagueness in Contracts, Patents and Regulations

    Directory of Open Access Journals (Sweden)

    Ismael Arinas Pellón

    2011-06-01

    Full Text Available In this genre analysis research paper, we compare U.S. patents, contracts, and regulations on technical matters with a focus upon the relation between vagueness and communicative purposes and subpurposes of these three genres. Our main interest is the investigation of intergeneric conventions across the three genres, based on the software analysis of three corpora (one for each genre, 1 million words per corpus. The result of the investigation is that intergeneric conventions are found at the level of types of expressed linguistic vagueness, but that intergeneric conventions at the level of actual formulations are rare. The conclusion is that at this latter level the influence from the situation type underlying the individual genre is more important than the overarching legal character of the genres, when we talk about introducing explicit vagueness in the text.El propósito de este artículo es comparar mediante herramientas de lingüística de corpus el uso de la vaguedad en contratos, legislación y patentes de los EE.UU. La comparación se centra en valorar hasta qué punto estos tres géneros comparten las mismas estrategias de vaguedad lingüística para lograr sus objetivos y sub-objetivos comunicativos. Los tres corpus compilados para este estudio comparten una combinación, tanto de lenguaje legal, como tecnológico y cada uno de ellos consta de algo más de un millón de tokens. El resultado de nuestra investigación apunta a que estos tres géneros comparten convenciones en el uso deliberado de tipos de vaguedad lingüística, pero la fraseología concreta de la vaguedad aplicada no es normalmente la misma. La conclusión es que, en este último nivel fraseológico, la situación subyacente en cada género es más importante que el común carácter legal de los géneros cuando se trata de introducir la vaguedad de forma explícita en el texto.

  3. 78 FR 37676 - Federal Acquisition Regulation; System for Award Management Name Change, Phase 1 Implementation

    Science.gov (United States)

    2013-06-21

    ... Services Administration (GSA)-- (1) Operates the web-based System for Award Management (SAM) Exclusions... System for Award Management (SAM) database for contracts awarded to support unusual and compelling needs... Representations and Certifications section of the System for Award Management (SAM) and its other data in SAM, as...

  4. 75 FR 48276 - Defense Federal Acquisition Regulation Supplement; Management of Unpriced Change Orders

    Science.gov (United States)

    2010-08-10

    ... to make requirements for DoD management and oversight of unpriced change orders consistent with those... management and oversight of undefinitized contract actions (UCAs). In the current DFARS, unpriced change... procedures. The rule makes requirements for DoD management and oversight of unpriced change orders consistent...

  5. Blockchain-based Smart Contracts in Waste Management : A Silver Bullet?

    NARCIS (Netherlands)

    G. (Guido) Ongena; Koen Smit; Jarno Boksebeld; Gerben Adams; Yorin Roelofs; Pascal Ravesteijn

    2018-01-01

    From the article: Blockchain technology may have the potential to fundamentally change society and we might currently witness the dawn of a cryptographically secured trust-free transactions economy. One relatively unexplored application domain is waste management. Incorrect waste management

  6. The use of Osseointegration and Orbital Implants in the Management of Orbital Exenteration or Severe Contracted Sockets

    Directory of Open Access Journals (Sweden)

    Emine Esra Karaca

    2014-03-01

    Full Text Available Objectives: To evaluate the results of bony integrated implants used in the management of exenterated or contracted sockets. Materials and Methods: Ten eyes of 10 cases underwent bony integrated implants for the management of exenterated (7 eyes or contracted (3 eyes sockets. The procedure was performed in two steps in a two-month period. The first step included placement of screws by preparing the osteotomy site, whereas the second step included implantation of magnetic implants over these screws that will adhere to the orbital implant. The patients were retrospectively evaluated for age, gender, etiology, surgical timing, history of radiotherapy, and time of application of epithesis. The presence of infection at the surgical site, implant loss, functional or cosmetic problems at the perisurgical area, the usage of epithesis during the social life were evaluated. Results: There were 7 female and 3 male patients. The mean age was 34 (5-75 years. The indications for enucleation or exenteration were: retinoblastoma (4 cases, malignant melanoma (2 cases, basal cell carcinoma (1 case, squamous cell carcinoma (1 case, rhabdomyosarcoma (1 case and sinoorbital mucormycosis (1 case. The epitheses were applied 3 to 156 months (mean 51 months following the intervention. All of the implantations were performed successfully. During follow-up, one case had lost the implant and one case had local infection that responded to antibiotic treatment. Three cases were reoperated and the implants were replaced after a 2-year follow-up time due to the deterioration of the magnetic effect of the implants. Conclusion: Bony integrated orbital implants have an important role in solution of esthetic problems encountered in the exenterated orbit and severe contracted socket. (Turk J Ophthalmol 2014; 44: 127-31

  7. The Potential Role of Contraction-Induced Myokines in the Regulation of Metabolic Function for the Prevention and Treatment of Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Brian P. Carson

    2017-05-01

    Full Text Available Skeletal muscle represents the largest organ in the body, comprises 36–42% of body weight, and has recently been recognized as having an endocrine function. Proteins expressed and released by muscle that have autocrine, paracrine, and endocrine bioactivities have been termed myokines. It is likely that muscle contraction represents the primary stimulus for the synthesis and secretion of myokines to enable communication with other organs such as the liver, adipose tissue, brain, and auto-regulation of muscle metabolism. To date, several hundred myokines in the muscle secretome have been identified, a sub-population of which are specifically induced by skeletal muscle contraction. However, the bioactivity of many of these myokines and the mechanism through which they act has either not yet been characterized or remains poorly understood. Physical activity and exercise are recognized as a central tenet in both the prevention and treatment of type 2 diabetes (T2D. Recent data suggest humoral factors such as muscle-derived secretory proteins may mediate the beneficial effects of exercise in the treatment of metabolic diseases. This mini-review aims to summarize our current knowledge on the role of contraction-induced myokines in mediating the beneficial effects of physical activity and exercise in the prevention and treatment of T2D, specifically glucose and lipid metabolism. Future directions as to how we can optimize contraction-induced myokine secretion to inform exercise protocols for the prevention and treatment of T2D will also be discussed.

  8. 41 CFR 101-1.4902-2053 - GSA Form 2053, Agency Consolidated Requirements for GSA Regulations and Other External Issuances.

    Science.gov (United States)

    2010-07-01

    ...-2053 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.49-Illustrations of Forms § 101-1.4902-2053 GSA... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true GSA Form 2053, Agency...

  9. The Role of a Human Factor and Psychological Contract in Managing the Knowledge in Conditions of Globalization

    Directory of Open Access Journals (Sweden)

    Joanna Rębisz

    2008-07-01

    Full Text Available The modern business world is characterized by dynamic, changing markets and continuous technological advance. This article focuses on an issue related to a definition of the meaning of a man and his location in an organization that works in conditions of globalization. Certainly, the meaning of human as the source of knowledge in the development of organization is not a new subject. Knowledge is intrinsically linked to people and enables them to act. Modern organizations base their theory on the knowledge they can exploit to improve the competence of the employee, his loyalty and commitment to the company which aims at the competitive predominance. The identification of knowledge is necessary for the effective implementation of knowledge management system. Above all, presented theoretical analysis pinpoints mainly on discussing a mans role and psychological contract in managing the knowledge.

  10. Managing Distrust-Induced Risk with Deposit in Supply Chain Contract Decisions

    Science.gov (United States)

    Han, Guanghua; Dong, Ming; Sun, Qi

    2014-01-01

    This paper studies the trust issue in a two-echelon supply chain information sharing process. In a supply chain, the retailer reports the forecasted demand to the supplier. Traditionally, the supplier's trust in the retailer's reported information is based on the retailer's reputation. However, this paper considers that trust is random and is also affected by the reputation and the demand gap. The supplier and retailer have been shown to have different evaluations regarding the degree of trust. Furthermore, distrust is inherently linked to perceived risk. To mitigate perceived risk, a two-stage decision process with an unpayback deposit contract is proposed. At the first stage, the supplier and the retailer negotiate the deposit contract. At the second stage, a Stackelberg game is used to determine the retailer's reported demand and the supplier's production quantity. We show that the deposits from the retailer's and supplier's perspectives are different. When the retailer's reported demand is equal to the supplier's forecasted demand, the retailer's evaluation of the deposit is more than that of supplier's. When the retailer's reported demand is equal to the retailer's forecasted demand, the deposit from the retailer's perspective is at the lowest level. PMID:25054190

  11. Managing Distrust-Induced Risk with Deposit in Supply Chain Contract Decisions

    Directory of Open Access Journals (Sweden)

    Guanghua Han

    2014-01-01

    Full Text Available This paper studies the trust issue in a two-echelon supply chain information sharing process. In a supply chain, the retailer reports the forecasted demand to the supplier. Traditionally, the supplier’s trust in the retailer’s reported information is based on the retailer’s reputation. However, this paper considers that trust is random and is also affected by the reputation and the demand gap. The supplier and retailer have been shown to have different evaluations regarding the degree of trust. Furthermore, distrust is inherently linked to perceived risk. To mitigate perceived risk, a two-stage decision process with an unpayback deposit contract is proposed. At the first stage, the supplier and the retailer negotiate the deposit contract. At the second stage, a Stackelberg game is used to determine the retailer’s reported demand and the supplier’s production quantity. We show that the deposits from the retailer’s and supplier’s perspectives are different. When the retailer’s reported demand is equal to the supplier’s forecasted demand, the retailer’s evaluation of the deposit is more than that of supplier’s. When the retailer’s reported demand is equal to the retailer’s forecasted demand, the deposit from the retailer’s perspective is at the lowest level.

  12. Public Internal Performance Contracting - Managing and financing energy-efficiency measures in public administrations

    International Nuclear Information System (INIS)

    Irrek, Wolfgang; Thomas, Stefan; Attali, Sophie; Benke, Georg; Borg, Nils; Figorski, Arkadiusz; Filipowicz, Mariusz; Labanca, Nicola; Pindar, Andrew; Ochoa, Amalia

    2005-01-01

    Public Internal Performance Contracting (PICO) is a type of in-house 'third-party' financing or energy performance contracting scheme. In theory, once triggered, PICO provides a 'perpetual motion' finance mechanism for public authorities by which energy efficiency savings fund new investments in an upward virtuous cycle. One unit of the public authority, e.g. the technical department, delivers the financial and technical energy efficiency service to another unit of the same public administration. Remuneration takes place through cross payments between these units, according savings made in energy costs. The initial investments require 'seed funds' to kick start the process, after which the cross payments provide sufficient means to fund further measures. How can the PICO mechanism be initiated in times of tight public budgets? What difficulties are faced during the implementation process and how can these be overcome? What kind of energy-efficiency measures is PICO best suited to? And what role can national and European policy play to facilitate implementation? These are the key questions that the EU-funded PICOLight project aimed to tackle. This was done through testing and disseminating the PICO schemes, first used in Germany, in six European countries, developing these further and making the necessary adaptations. PICO schemes were piloted in seven public administrations with the technical focus on energy-efficient lighting retrofits. The experiences gathered in these pilot projects should help to introduce PICO schemes on a larger scale in public administrations in Europe. The paper presents the preliminary results from these pilot projects

  13. Managing distrust-induced risk with deposit in supply chain contract decisions.

    Science.gov (United States)

    Han, Guanghua; Dong, Ming; Sun, Qi

    2014-01-01

    This paper studies the trust issue in a two-echelon supply chain information sharing process. In a supply chain, the retailer reports the forecasted demand to the supplier. Traditionally, the supplier's trust in the retailer's reported information is based on the retailer's reputation. However, this paper considers that trust is random and is also affected by the reputation and the demand gap. The supplier and retailer have been shown to have different evaluations regarding the degree of trust. Furthermore, distrust is inherently linked to perceived risk. To mitigate perceived risk, a two-stage decision process with an unpayback deposit contract is proposed. At the first stage, the supplier and the retailer negotiate the deposit contract. At the second stage, a Stackelberg game is used to determine the retailer's reported demand and the supplier's production quantity. We show that the deposits from the retailer's and supplier's perspectives are different. When the retailer's reported demand is equal to the supplier's forecasted demand, the retailer's evaluation of the deposit is more than that of supplier's. When the retailer's reported demand is equal to the retailer's forecasted demand, the deposit from the retailer's perspective is at the lowest level.

  14. Safety Culture for Regulator Competence Management in Embarking States

    International Nuclear Information System (INIS)

    Kandil, M.

    2016-01-01

    Full text: Safety is based on preventive actions where the ability of a regulatory body to fulfill its responsibilities depends largely on the competence of its staff. Building employees’ skills and knowledge is an investment for each employee and in the future of the organization. This building must be the competence of its staff integration with their safety culture, the essential to ensure competent human resources as required in the IAEA safety standards and other documents, in which the need and importance of ensuring regulatory competence is emphasized. As it involves both operational and management issues, safety culture is a sensitive topic for regulators whose role is to ensure compliance with safety requirements and not to intervene in management decisions. A number of embarking States are aspiring to develop nuclear power generation and this means that, among other things, regulatory bodies have to be established and rapidly expanded. This paper reports major considerations on the integration of safety culture with an adequate competence management system for regulators in embarking states. (author

  15. The role of psychological contract on employee commitment and organisational citizenship behaviour: A study of Indonesian young entrepreneurs in management action

    OpenAIRE

    Anggraeni, Ade I.; Dwiatmadja, Christantius; Yuniawan, Ahyar

    2017-01-01

    Orientation: This study aims to analyse the entrepreneurship-driven reasons and characteristics of employee management of the young generation, by analysing the role of psychological contract on employee commitment and organisational citizenship behaviour in the light of the characteristics of the millennial generation as the owners of small and medium-sized enterprises. Research purpose: The main objective of this study was to empirically analyse the effect of the psychological contract ...

  16. 48 CFR 970.5227-10 - Patent rights-management and operating contracts, nonprofit organization or small business firm...

    Science.gov (United States)

    2010-10-01

    ... exceptional circumstance subject inventions. (3) Treaties and international agreements. Any rights acquired by..., or public use. The Contractor will file patent applications in additional countries or international... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Patent rights-management...

  17. Infectious waste management in Japan: A revised regulation and a management process in medical institutions

    International Nuclear Information System (INIS)

    Miyazaki, M.; Une, H.

    2005-01-01

    In Japan, the waste management practice is carried out in accordance with the Waste Disposal Law of 1970. The first rule of infectious waste management was regulated in 1992, and infectious wastes are defined as the waste materials generated in medical institutions as a result of medical care or research which contain pathogens that have the potential to transmit infectious diseases. Revised criteria for infectious waste management were promulgated by the Ministry of Environment in 2004. Infectious waste materials are divided into three categories: the form of waste; the place of waste generation; the kind of infectious diseases. A reduction of infectious waste is expected. We introduce a summary of the revised regulation of infectious waste management in this article

  18. Dynamic contracting : An asset management tool in controlling infrastructure maintenance activities

    NARCIS (Netherlands)

    Demirel, H.C.; de Ridder, H.A.J.; Hertogh, M.J.C.M.

    2013-01-01

    Infrastructure road network is a complex system in a fast changing complicated environment and therefore subject to change. The changes refer to demands, requirements, regulations and financial possibilities as well as advanced technologies. Therefore outsourcing maintenance activities are rather

  19. Management councils and regulation: public assistance in times of transition

    Directory of Open Access Journals (Sweden)

    Carla Cecília Rodrigues Almeida

    2009-10-01

    Full Text Available This article analyzes the role of municipal public assistance councils in the regulation of civil society organizations classified as social welfare organizations. We draw attention to the importance that these councils have for the operationalization of the more general principles governing the country’s social welfare/public assistance policies. Focusing on the regulatory role that management councils’ take on, we seek to understand, on the one hand, the wider institutional environment to which they belong and, on the other, their power to remodel a particular type of associativism which until very recently was identified and identified itself as philanthropical. Keywords: municipal councils, social welfare, Sistema Único de Assistência Social, regulation, public assistance entities.

  20. 78 FR 36723 - Federal Management Regulation (FMR); Restrictions on International Transportation of Freight and...

    Science.gov (United States)

    2013-06-19

    ..., Sequence 1] RIN 3090-AJ34 Federal Management Regulation (FMR); Restrictions on International Transportation... Administration (GSA). ACTION: Proposed rule. SUMMARY: GSA is proposing to amend the Federal Management Regulation... Federal Management Regulation (FMR) to state clearly that this part applies to all agencies and wholly...

  1. Review and Necessity of Recognizing Risk Management in Civil Projects and Contracts

    OpenAIRE

    VOSOUGHI, Pouyan; VOSOUGHI, Vandad

    2015-01-01

    Proper risk management is the reason for which risk (and its various types) is assigned to that section that is able to manage it in the best way but is the section which is able to manage the risk in the best way the same party that has the most effect on the probability of an adverse occurrence or is the section that is able to manage the results in the best way after the adverse occurrence. Now by considering the size, nature and complexity of the projects, the necessity of having the tech...

  2. Contract design

    International Nuclear Information System (INIS)

    Bradley, P.

    2006-01-01

    The current state of the electric power industry in Ontario was discussed with particular reference to the procurement of contracts and why the Ontario Power Authority (OPA) must be contracting to resolve many of Ontario's electricity issues. As Ontario increasingly relies on imports and natural gas-fired generation, the price of electricity continues to rise given that supply is at a low level. In addition to the generation gap, there are also several transmission constrained areas in Ontario, particularly in the Greater Toronto Area (GTA). The OPA announced 2 projects totalling 1900 MW to relieve congestion. According to the Independent Electricity System Operator (IESO), the total potential opportunity for new generation by 2015 is about 5,000 to 7,000 megawatts. OPA is expected to launch procurement processes for up to 1000 MW of cogeneration, 250 MW of province-wide conservation initiatives, 1900 MW of generation in the western part of the GTA, and 600 MW of generation in downtown Toronto. New nuclear capacity is also anticipated in addition to renewables and conservation/demand management (CDM) initiatives. The OPA's competitive procurement processes will include requests for expressions of interest, requests for qualifications and requests for proposals. The challenge of balancing the technical complexities and realities of procuring generation assets with the need for a fair procurement process was discussed. Contracts will be designed to react to market signals and will include 3 styles: tariff style, tolling style and standard offer contract. OPA will make every effort to balance generator and ratepayer interests. 6 figs

  3. Effective management of regulator RI/FS comments

    International Nuclear Information System (INIS)

    Wolinsky, S.M.; Lojek, D.; George, R.D.; Houser, S.M.; Strimbu, M.J.

    1995-01-01

    This paper describes a successful strategy that facilitates regulatory approval of CERCLA documents required by compliance agreement and CERCLA, based on the experience of Operable Unit 1, Waste Storage Area, of the Fernald Environmental Management Project (FEMP). This strategy, which has become the site standard at the FEMP, was instrumental in obtaining regulator approval of the OU1 RI and FS, and early approval of the Record of Decision during a very tight compliance agreement-driven schedule. This strategy can be applied at any DOE Superfund site, especially where there is need to recover lost schedule, an incentive to meet milestones early, a need to improve the relationship between the DOE and the regulators, or where the regulatory agencies have historically provided a large volume of comments on CERCLA documents. The strategy focuses on early identification and resolution of issues relating to draft RI/FS documents, as raised in regulatory agency review comments. This pro-active strategy has the potential for schedule and cost savings, as well as for improved communication between DOE and the regulators. The strategy includes preparation of a separate comment response document, integration of comment responses with RI/FS documents, development of a database of agency comments and their resolution, and sharing lessons learned with preparers of subsequent RI/FS documents. The paper provides background on the FEMP and describes the FEMP comment response strategy; DOE and regulator interface; the Sitewide Comment Database; networked electronic file management; the process for classifying, analyzing, and responding to comments; integration with base RI/FS documents; and a conclusion

  4. Effective management of regulator RI/FS comments

    Energy Technology Data Exchange (ETDEWEB)

    Wolinsky, S.M.; Lojek, D.; George, R.D.; Houser, S.M.; Strimbu, M.J.

    1995-12-31

    This paper describes a successful strategy that facilitates regulatory approval of CERCLA documents required by compliance agreement and CERCLA, based on the experience of Operable Unit 1, Waste Storage Area, of the Fernald Environmental Management Project (FEMP). This strategy, which has become the site standard at the FEMP, was instrumental in obtaining regulator approval of the OU1 RI and FS, and early approval of the Record of Decision during a very tight compliance agreement-driven schedule. This strategy can be applied at any DOE Superfund site, especially where there is need to recover lost schedule, an incentive to meet milestones early, a need to improve the relationship between the DOE and the regulators, or where the regulatory agencies have historically provided a large volume of comments on CERCLA documents. The strategy focuses on early identification and resolution of issues relating to draft RI/FS documents, as raised in regulatory agency review comments. This pro-active strategy has the potential for schedule and cost savings, as well as for improved communication between DOE and the regulators. The strategy includes preparation of a separate comment response document, integration of comment responses with RI/FS documents, development of a database of agency comments and their resolution, and sharing lessons learned with preparers of subsequent RI/FS documents. The paper provides background on the FEMP and describes the FEMP comment response strategy; DOE and regulator interface; the Sitewide Comment Database; networked electronic file management; the process for classifying, analyzing, and responding to comments; integration with base RI/FS documents; and a conclusion.

  5. 41 CFR 301-73.202 - Can contract fares be used for personal travel?

    Science.gov (United States)

    2010-07-01

    ... used for personal travel? 301-73.202 Section 301-73.202 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 73-TRAVEL... travel? No. ...

  6. Some points in legal regulation of radioactive waste management

    International Nuclear Information System (INIS)

    Tikhankin, Anatoly; Levin, Alexander

    1999-01-01

    In Russia, the system of the legal acts regulating radioactive waste management is now in progress. Development of the federal norms and regulations on the use of atomic energy is a responsibility of Gosatomnazdor. This presentation describes in detail the work done by Gosatomnadzor in 1997/1998 on the development of the legal documents regulating the management of radioactive waste and spent nuclear material. A document of special importance is ''Burial of Radioactive Wastes. Principles, Criteria and Basic Safety Requirements''. This is discussed in some detail. For all stages of radioactive waste management, safety criteria for population and personnel are set up in strict analogy with current legislation for any other type of radiological hazard. A combined, or hybrid, safety criterion is suggested for estimation of long-term safety of radioactive waste repository systems, for the period upon termination of the established administrative monitoring after closing the repository. A dose criterion is accepted for normal radiation exposure and a risk criterion for potential radiation exposure. The safety of radioactive waste repository should be ensured by means of graded safeguard throughout the entire period of burial. Graded safeguard is based on independent barriers on the way of ionising radiation and emission of radioactive substances into the environment and protection and maintenance of these barriers. Examples show how the provisions of the document are applied in practice in the permafrost area of Russia. Permafrost soil has low water permeability, which is significant because underground water is the main transport medium in case of a leakage from a repository

  7. Regulatory control, nuclear safety regulation and waste management in Spain

    International Nuclear Information System (INIS)

    Martin, A.

    2000-01-01

    This article presents the challenges that faces the spanish regulatory authority. The deregulation of electricity industry imposes severe changes in nuclear power economics and forces nuclear power to compete with other sources of electricity. A pressure is perceived for regulatory effectiveness primarily since the cost of regulation is a component of the cost of the product. This effectiveness gain in regulatory control will be reached through systematic strategic analysis, formulation and implementation. The regulatory aspects of plant life extension and of waste management are examined

  8. Contract Design: Financial Options and Risk.

    Science.gov (United States)

    Mühlbacher, Axel C; Amelung, Volker E; Juhnke, Christin

    2018-01-12

    Integrated care systems as well as accountable care organisations (ACOs) in the US and similar concepts in other countries are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. By this the total costs of care shall be reduced. When designing healthcare options contractors are faced with a variety of financial options. The costs of market utilisation are highly relevant for the conception of healthcare contracts; furthermore contract-specific investments are an obstacle to the efficient operation of ACOs. A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. This article is the second in a row of three that are all published in this issue and contribute to a specific issue in designing healthcare contracts. The first dealt with the organisation of contracts and information asymmetries, while part 3 concludes with the question of risk management and evaluation. The specific research question of this second article focusses on the financial options and reimbursement schemes that are available to define healthcare contracts. A healthcare contract is a relational contract, which determines the level of reimbursement, the scope of services and the quality between service providers and payers, taking account of the risks relating to population and performance. A relational contract is an agreement based upon assumption of a longer timeframe. A major obstacle to the practical implementation of healthcare contracts is the prognosis of the inflows and outflows due to the actuarial risks of the insured population. Financing conditions and reimbursement arrangements that are based on a prospectively determined fixed price, have a significant drawback: it is very difficult to take the differences in health status and the utilisation of distinct insured clientele

  9. Perceived barriers to utilizing maternal and neonatal health services in contracted-out versus government-managed health facilities in the rural districts of Pakistan.

    Science.gov (United States)

    Riaz, Atif; Zaidi, Shehla; Khowaja, Asif Raza

    2015-03-06

    A number of developing countries have contracted out public health facilities to the Non-Government Organizations (NGOs) in order to improve service utilization. However, there is a paucity of in-depth qualitative information on barriers to access services as a result of contracting from service users' perspective. The objective of this study was to explore perceived barriers to utilizing Maternal and Neonatal Health (MNH) services, in health facilities contracted out by government to NGO for service provision versus in those which are managed by government (non-contracted). A community-based qualitative exploratory study was conducted between April to September 2012 at two contracted-out and four matched non-contracted primary healthcare facilities in Thatta and Chitral, rural districts of Pakistan. Using semi-structured guide, the data were collected through thirty-six Focus Group Discussions (FGDs) conducted with mothers and their spouses in the catchment areas of selected facilities. Thematic analysis was performed using NVivo version 10.0 in which themes and sub-themes emerged. Key barriers reported in contracted sites included physical distance, user charges and familial influences. Whereas, poor functionality of health centres was the main barrier for non-contracted sites with other issues being comparatively less salient. Decision-making patterns for participants of both catchments were largely similar. Spouses and mother-in-laws particularly influenced the decision to utilize health facilities. Contracting out of health facility reduces supply side barriers to MNH services for the community served but distance, user charges and low awareness remain significant barriers. Contracting needs to be accompanied by measures for transportation in remote settings, oversight on user fee charges by contractor, and strong community-based behavior change strategies. © 2015 by Kerman University of Medical Sciences.

  10. Perceived Barriers to Utilizing Maternal and Neonatal Health Services in Contracted-Out Versus Government-Managed Health Facilities in the Rural Districts of Pakistan

    Directory of Open Access Journals (Sweden)

    Atif Riaz

    2015-05-01

    Full Text Available Background A number of developing countries have contracted out public health facilities to the Non-Government Organizations (NGOs in order to improve service utilization. However, there is a paucity of in-depth qualitative information on barriers to access services as a result of contracting from service users’ perspective. The objective of this study was to explore perceived barriers to utilizing Maternal and Neonatal Health (MNH services, in health facilities contracted out by government to NGO for service provision versus in those which are managed by government (non-contracted. Methods A community-based qualitative exploratory study was conducted between April to September 2012 at two contracted-out and four matched non-contracted primary healthcare facilities in Thatta and Chitral, rural districts of Pakistan. Using semi-structured guide, the data were collected through thirty-six Focus Group Discussions (FGDs conducted with mothers and their spouses in the catchment areas of selected facilities. Thematic analysis was performed using NVivo version 10.0 in which themes and sub-themes emerged. Results Key barriers reported in contracted sites included physical distance, user charges and familial influences. Whereas, poor functionality of health centres was the main barrier for non-contracted sites with other issues being comparatively less salient. Decision-making patterns for participants of both catchments were largely similar. Spouses and mother-in-laws particularly influenced the decision to utilize health facilities. Conclusion Contracting out of health facility reduces supply side barriers to MNH services for the community served but distance, user charges and low awareness remain significant barriers. Contracting needs to be accompanied by measures for transportation in remote settings, oversight on user fee charges by contractor, and strong communitybased behavior change strategies.

  11. Challenges in Regulating Radiation Sources and Associated Waste Management

    International Nuclear Information System (INIS)

    Shehzad, A.

    2016-01-01

    Radiation sources are widely used in the fields of medical, industry, agriculture, research, etc. Owing to the inherent risk of exposure to ionizing radiations while using the radiation sources and management of associated waste, safety measures are of utmost importance including robust regulatory control. Pakistan Nuclear Regulatory Authority (PNRA) is responsible for supervising all matters pertaining to nuclear safety and radiation protection in the country. Since its inception, PNRA has made rigorous efforts to regulate the radiation facilities for which regulatory framework was further strengthened by taking into account international norms/practices and implemented afterwards. However, due to vibrant use of these facilities, there are numerous challenges being faced while implementing the regulatory framework. These challenges pertains to shielding design of some facilities, control over service provider for QC/repair maintenance of radiation equipment, assessment of patient doses, and establishment of national diagnostic reference levels for radiological procedures. Further, the regulatory framework also delineate requirements to minimize the generation of associated radioactive waste as low as practicable. The requirements also necessitates that certain sealed radioactive sources (SRS) are returned to the supplier upon completion of their useful life, while other radioactive sources are required to be transported for storage at designated radioactive waste storage facilities in the country, which requires commitment from the licensee. This paper will briefly describe the challenges in regulating the radiation sources and issues related to the waste management associated with these facilities. (author)

  12. Sustainability Reporting in Fishing Industry Management - Regulation versus Voluntarism

    Directory of Open Access Journals (Sweden)

    Susan Wild

    2008-09-01

    Full Text Available A growing number of major corporations and industry organizations now overtly advocate thegeneral concept of corporate social and environmental responsibility, commonly emphasising the‘business case’ for such behaviour on the basis that it is ‘good for business’. Many now report totheir stakeholders on a voluntaristic basis a range of information regarding their impacts on thesocial and physical environment in which they operate.Intrinsic to the business case model is the argument that an optimal balance between the needs ofeconomic growth and the sustainable management of natural resources can best be attainedthrough the conventional mechanisms of corporate governance and voluntary corporate activity,rather than by imposition of governmental regulation. This view implies, however, that wherethe exigencies of environmental sustainability conflict with those of economic imperatives, thelatter must take precedence.A view oppositional to that of the business case instead promotes an intensified interventionistapproach towards natural resource management, advocating increased governmental regulationand control, including the mandating, standardization and independent verification of corporatesustainability reporting. This view gives precedence to public good concepts of natural resourcemanagement, prioritising intra- and inter-generational equity and human rights theories as tonatural resource distribution, and challenges traditional economic approaches to the relationalintersects of business, politics and environment science.This paper considers the relative claims for efficacy in achieving desirable corporateenvironmental behaviours of the business case and voluntary self-regulation model, vis-à-visthose for extended mandatory governmental control, utilizing the exemplar of voluntarysustainability reporting in the New Zealand fishing industry.

  13. Management Earnings Forecasts as a Performance Target in Executive Compensation Contracts

    OpenAIRE

    Shota Otomasa; Atsushi Shiiba; Akinobu Shuto

    2015-01-01

    This paper investigates whether and how Japanese firms use management earnings forecasts as a performance target for determining executive cash compensation. Consistent with the implications of the principal-agent theory, we find that the sensitivity of executive cash compensation varies with the extent to which realized earnings exceed initial management forecasts. In particular, we find that, for a sample of Japanese firms comprising 14,899 firm-year observations from 2005 to 2012, the exec...

  14. 48 CFR 926.7104 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 926.7104... 1993. 926.7104 Contract clause. The contracting officer shall insert the clause at 48 CFR (DEAR) 952.226-74, Displaced Employee Hiring Preference, in contracts (except for contracts for commercial items...

  15. 48 CFR 837.403 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 837.403... OF CONTRACTING SERVICE CONTRACTING Nonpersonal Health Care Services 837.403 Contract clause. The contracting officer shall insert the clause at 852.237-7, Indemnification and medical liability insurance, in...

  16. 48 CFR 822.305 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 822.305... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Contract Work Hours and Safety Standards Act 822.305 Contract clause. The contracting officer shall insert the clause at 852.222-70, Contract Work...

  17. 48 CFR 811.503 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 811.503... ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Liquidated Damages 811.503 Contract clause. When the contracting... contracting officer must include the clause in 852.211-74, Liquidated damages, in the contract. ...

  18. 48 CFR 916.203-4 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 916.203-4 Section 916.203-4 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 916.203-4 Contract clauses. (d)(2) The...

  19. Legal Regulations for Surrogacy Contract%浅谈代孕合同之法律规制问题

    Institute of Scientific and Technical Information of China (English)

    陈爱玲

    2012-01-01

    With the development of artificial reproductive technology,surrogacy has caused lot of legal problems when it benefits human being,which has become a new issue in legal field.Although there exist practices and agencies of surrogacy,the legislative blank cannot meet the need of our time.This paper,starting from the conception of surrogacy contract,analyses the legalization of surrogacy contract and raises the thought of legalizing the surrogacy contract.%随着人工生殖技术的发展,代孕在造福人类的同时也带来一系列法律上的问题,成为法学界一个崭新的研究课题。现实社会中已经大量存在着代孕行为及一些中介机构,然而我国对代孕合同的立法空白显然不符合时代需求,本文从代孕合同的概念入手,首先分析了代孕合同的合法化,之后提出了对代孕合同进行法律规制的构想。

  20. 48 CFR 833.215 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 833.215 Section 833.215 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 833.215 Contract clause. The contracting...

  1. 48 CFR 432.412 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contract clause. 432.412 Section 432.412 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.412 Contract clause. The decision...

  2. Management system for regulating transport of radioactive material

    International Nuclear Information System (INIS)

    Lopez Vietri, Jorge; Capadona, Nancy; Barenghi, Leonardo

    2008-01-01

    Full text: The objective of this paper is to describe the main characteristics and fundamentals of the Nuclear regulatory Authority's (Autoridad Regulatoria Nuclear, ARN) management system applied to the regulation of transport of radioactive material, in Argentina. In the frame of ARN's quality policy, 'Protection against ionizing radiation on transport of radioactive materials' was selected as one of the regulatory processes, named TRM process from now on. ARN's quality management system is integrally based on ISO 9000 system addressed to help organizations in designing and implementing their quality management systems. TRM process was split into five sub processes in order to facilitate the implementation of quality system. Such sub processes were defined taking account of the main functions developed by ARN in the branch of safe transport of radioactive materials and are listed below: 1) Development and updating of standards and regulatory guides; 2) Licensing of packages, special radioactive materials and consignments of radioactive materials; 3) Compliance assurance during the transport of radioactive materials, and 4) Training, advising and communications. For each of these sub processes were specified their objectives, inputs, activities and outputs, the clients and stakeholders, responsibilities, supporting documents, control of documents and records, control of non-conformances, monitoring and measurements, audits, feedback and improvement. It was decided to develop a quality plan to organize and manage activities to meet quality requirements, to optimize the use of limited resources of the organization and to be used as a basis for monitoring and assessing compliance with the requirements, both internal and external. Supporting documents for sub processes were issued, validated, reviewed and improved as an essential point to implement continuous improving. Simultaneously, some indexes were defined to monitor and measure the sub processes as a way to show

  3. 48 CFR 970.1504-1-3 - Special considerations: Laboratory management and operation.

    Science.gov (United States)

    2010-10-01

    ...: Laboratory management and operation. 970.1504-1-3 Section 970.1504-1-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Contracting by Negotiation 970.1504-1-3 Special considerations: Laboratory management and operation. (a) For the management...

  4. Aligning drivers, contract, and management of IT-outsourcing relationships: a type-dependent model

    DEFF Research Database (Denmark)

    Arenfeldt, Katrine; Corty Dam, Amalie; Fenger, Kim Harder

    2017-01-01

    In today’s competitive business environment, information technology outsourcing has become a wide-spread reality across all industries and sectors. Researchers have investigated this complex phenomenon from various angles, and established a sound knowledge base regarding the drivers, management, ...

  5. DCASR (Defense Contract Administration Service Region), Boston Is the Customer’s Voice. Total Quality Management

    Science.gov (United States)

    1989-10-01

    been Hoshin Kanri , the Japanese term for Management by Planning, which loosely translates as "compass" and "sextant". When we initially began the...commitment empowered us to develop a plan which would clearly point the direction ( Hoshin ), as well as provide the structure for getting there ( Kanri

  6. Privacy Management Service Contracts as a New Business Opportunity for Operators

    NARCIS (Netherlands)

    L-F. Pau (Louis-François)

    2006-01-01

    textabstractRecognizing the importance of privacy management as a business process and a business support process, this paper proposes the use of service level agreements (SLA’s) around privacy features, including qualitative and quantitative ones. Privacy metrics are defined by both parties with

  7. Integral Risk Management for DBFM Tenders and Contracts in the Netherlands

    NARCIS (Netherlands)

    Wong, J.; Berkelaar, R.; Pekelharing, H.

    2015-01-01

    This paper presents an overview of an integral risk management approach with emphasis on the relationships with the costing and scheduling processes. Forms of uncertainty related to project planning are classified and implemented in the probabilistic costing and scheduling processes. Furthermore,

  8. 48 CFR 16.202 - Firm-fixed-price contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Firm-fixed-price contracts. 16.202 Section 16.202 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 16.202 Firm-fixed-price...

  9. Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI.

    Science.gov (United States)

    Hurtado, Erica; Cilleros, Víctor; Nadal, Laura; Simó, Anna; Obis, Teresa; Garcia, Neus; Santafé, Manel M; Tomàs, Marta; Halievski, Katherine; Jordan, Cynthia L; Lanuza, Maria A; Tomàs, Josep

    2017-01-01

    The neurotrophin brain-derived neurotrophic factor (BDNF) acts via tropomyosin-related kinase B receptor (TrkB) to regulate synapse maintenance and function in the neuromuscular system. The potentiation of acetylcholine (ACh) release by BDNF requires TrkB phosphorylation and Protein Kinase C (PKC) activation. BDNF is secreted in an activity-dependent manner but it is not known if pre- and/or postsynaptic activities enhance BDNF expression in vivo at the neuromuscular junction (NMJ). Here, we investigated whether nerve and muscle cell activities regulate presynaptic conventional PKC (cPKCα and βI) via BDNF/TrkB signaling to modulate synaptic strength at the NMJ. To differentiate the effects of presynaptic activity from that of muscle contraction, we stimulated the phrenic nerve of rat diaphragms (1 Hz, 30 min) with or without contraction (abolished by μ-conotoxin GIIIB). Then, we performed ELISA, Western blotting, qRT-PCR, immunofluorescence and electrophysiological techniques. We found that nerve-induced muscle contraction: (1) increases the levels of mature BDNF protein without affecting pro-BDNF protein or BDNF mRNA levels; (2) downregulates TrkB.T1 without affecting TrkB.FL or p75 neurotrophin receptor (p75) levels; (3) increases presynaptic cPKCα and cPKCβI protein level through TrkB signaling; and (4) enhances phosphorylation of cPKCα and cPKCβI. Furthermore, we demonstrate that cPKCβI, which is exclusively located in the motor nerve terminals, increases activity-induced acetylcholine release. Together, these results show that nerve-induced muscle contraction is a key regulator of BDNF/TrkB signaling pathway, retrogradely activating presynaptic cPKC isoforms (in particular cPKCβI) to modulate synaptic function. These results indicate that a decrease in neuromuscular activity, as occurs in several neuromuscular disorders, could affect the BDNF/TrkB/PKC pathway that links pre- and postsynaptic activity to maintain neuromuscular function.

  10. Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI

    Directory of Open Access Journals (Sweden)

    Erica Hurtado

    2017-05-01

    Full Text Available The neurotrophin brain-derived neurotrophic factor (BDNF acts via tropomyosin-related kinase B receptor (TrkB to regulate synapse maintenance and function in the neuromuscular system. The potentiation of acetylcholine (ACh release by BDNF requires TrkB phosphorylation and Protein Kinase C (PKC activation. BDNF is secreted in an activity-dependent manner but it is not known if pre- and/or postsynaptic activities enhance BDNF expression in vivo at the neuromuscular junction (NMJ. Here, we investigated whether nerve and muscle cell activities regulate presynaptic conventional PKC (cPKCα and βI via BDNF/TrkB signaling to modulate synaptic strength at the NMJ. To differentiate the effects of presynaptic activity from that of muscle contraction, we stimulated the phrenic nerve of rat diaphragms (1 Hz, 30 min with or without contraction (abolished by μ-conotoxin GIIIB. Then, we performed ELISA, Western blotting, qRT-PCR, immunofluorescence and electrophysiological techniques. We found that nerve-induced muscle contraction: (1 increases the levels of mature BDNF protein without affecting pro-BDNF protein or BDNF mRNA levels; (2 downregulates TrkB.T1 without affecting TrkB.FL or p75 neurotrophin receptor (p75 levels; (3 increases presynaptic cPKCα and cPKCβI protein level through TrkB signaling; and (4 enhances phosphorylation of cPKCα and cPKCβI. Furthermore, we demonstrate that cPKCβI, which is exclusively located in the motor nerve terminals, increases activity-induced acetylcholine release. Together, these results show that nerve-induced muscle contraction is a key regulator of BDNF/TrkB signaling pathway, retrogradely activating presynaptic cPKC isoforms (in particular cPKCβI to modulate synaptic function. These results indicate that a decrease in neuromuscular activity, as occurs in several neuromuscular disorders, could affect the BDNF/TrkB/PKC pathway that links pre- and postsynaptic activity to maintain neuromuscular function.

  11. 48 CFR 542.1107 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Production Surveillance and Reporting 542.1107 Contract... clause may be used in indefinite-delivery definite-quantity contracts for Stock or Special Order Program...

  12. 42 CFR 422.504 - Contract provisions.

    Science.gov (United States)

    2010-10-01

    ...) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Application Procedures and Contracts for Medicare Advantage... determinations of amounts payable under the contract. (iv) Properly reflect all direct and indirect costs claimed..., contracts, and subcontracts. (vi) Franchise, marketing, and management agreements. (vii) Schedules of...

  13. Aligning drivers, contract, and management of IT-outsourcing relationships: a type-dependent model

    DEFF Research Database (Denmark)

    Arenfeldt, Katrine; Corty Dam, Amalie; Fenger, Kim Harder

    2017-01-01

    In today’s competitive business environment, information technology outsourcing has become a wide-spread reality across all industries and sectors. Researchers have investigated this complex phenomenon from various angles, and established a sound knowledge base regarding the drivers, management......, and success factors related to IT outsourcing. However, little is known about the relationship between outsourcing drivers and goals on the one hand, and contractual and managerial aspects on the other hand. To overcome this gap, this study presents a synthesized conceptual model of existing literature...... that relates aspects of contractual governance and relationship management to three generic types of IT outsourcing, based on their underlying drivers: task-based, process-based, and partnership-based outsourcing. Our model identifies the specific contractual and managerial factors relevant for each type...

  14. Avoiding dual regulation of the Civilian Radioactive Waste Management Program

    International Nuclear Information System (INIS)

    Vlahakis, J.G.; Palabrica, R.J.

    1994-01-01

    The Office of Civilian Radioactive Waste Management (RW) has successfully negotiated the issuance of a Department of Energy (DOE) Headquarters Order that provides for exemption of RW from certain DOE directives. This exemption assures precedence of Nuclear Regulatory Commission (NRC) requirements in radiation protection, nuclear safety (including quality assurance), and safeguards and security of nuclear materials. This Order is necessary to avoid the unwarranted cost and potential confusion resulting from dual regulation of RW facilities and activities by DOE and NRC. Development of this Order involved a systematic review of applicable DOE directives and NRC requirements to identify potential overlaps and duplication when applied to the RW program. Following this review and extensive negotiations with appropriate DOE organizations responsible for directives development, this Order was issued as HQ 1321.1 on December 22, 1993

  15. The regulation of radioactive waste management in Canada

    International Nuclear Information System (INIS)

    1978-01-01

    Radioactive waste management facilities are subject to the Atomic Energy Control Regulations under jurisdiction of the Atomic Energy Control Board. Before such a facility can be constructed and permitted to operate, the applicant must obtain from the AECB in turn, site approval, a construction approval, and an operating licence, different considerations (e.g. geological, security) being given priority at each stage. Operating licences are normally valid for one year only, their renewal being dependent on observance, by the applicant, of the procedures and conditions laid down by the Board. Licensing document No.23 offers guidance on the requirements involved both generally and in relation to specific methods of waste storage and disposal. A copy of this document is attached to the present paper. (NEA) [fr

  16. Using Blockchain Technology and Smart Contracts for Access Management in IoT devices

    OpenAIRE

    Bagchi, Rupsha

    2017-01-01

    The Internet of Things is a proliferating industry, which is transforming many homes and businesses, making them smart. However, the rapid growth of these devices and the interactions between these devices, introduces many challenges including that of a secure management system for the identities and interactions of the devices. While the centralized model has worked well for many years, there is a risk of the servers becoming bottlenecks and a single point of failure, thereby making them vul...

  17. 14 CFR 1310.11 - Regulations of the Office of Management and Budget.

    Science.gov (United States)

    2010-01-01

    ... Budget. (a) The regulations in this part supplement the regulations of the Office of Management and... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Regulations of the Office of Management and Budget. 1310.11 Section 1310.11 Aeronautics and Space AIR TRANSPORTATION SYSTEM STABILIZATION AIR...

  18. 78 FR 29245 - U.S. General Services Administration Federal Property Management Regulations; Administrative Wage...

    Science.gov (United States)

    2013-05-20

    ... Federal Property Management Regulations; Administrative Wage Garnishment AGENCY: Office of the Chief... the U.S. General Services Administration Property Management Regulation (GSPMR) to remove information... Administrative Wage Garnishment Code of Federal Regulations (CFR) Parts affected are as follows: 41 CFR part 105...

  19. Mosquito population regulation and larval source management in heterogeneous environments.

    Directory of Open Access Journals (Sweden)

    David L Smith

    Full Text Available An important question for mosquito population dynamics, mosquito-borne pathogen transmission and vector control is how mosquito populations are regulated. Here we develop simple models with heterogeneity in egg laying patterns and in the responses of larval populations to crowding in aquatic habitats. We use the models to evaluate how such heterogeneity affects mosquito population regulation and the effects of larval source management (LSM. We revisit the notion of a carrying capacity and show how heterogeneity changes our understanding of density dependence and the outcome of LSM. Crowding in and productivity of aquatic habitats is highly uneven unless egg-laying distributions are fine-tuned to match the distribution of habitats' carrying capacities. LSM reduces mosquito population density linearly with coverage if adult mosquitoes avoid laying eggs in treated habitats, but quadratically if eggs are laid in treated habitats and the effort is therefore wasted (i.e., treating 50% of habitat reduces mosquito density by approximately 75%. Unsurprisingly, targeting (i.e. treating a subset of the most productive pools gives much larger reductions for similar coverage, but with poor targeting, increasing coverage could increase adult mosquito population densities if eggs are laid in higher capacity habitats. Our analysis suggests that, in some contexts, LSM models that accounts for heterogeneity in production of adult mosquitoes provide theoretical support for pursuing mosquito-borne disease prevention through strategic and repeated application of modern larvicides.

  20. 41 CFR 109-27.102-50 - Systems contracting.

    Science.gov (United States)

    2010-07-01

    ...-INVENTORY MANAGEMENT 27.1-Stock Replenishment § 109-27.102-50 Systems contracting. Systems contracting may... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Systems contracting. 109-27.102-50 Section 109-27.102-50 Public Contracts and Property Management Federal Property Management...

  1. Using SCOR as a Supply Chain Management Framework for Government Agency Contract Requirements

    Science.gov (United States)

    Paxton, Joe

    2010-01-01

    Enterprise Supply Chain Management consists of: Specifying suppliers to support inter-program and inter-agency efforts. Optimizing inventory levels and locations throughout the supply chain. Executing corrective actions to improve quality and lead time issues throughout the supply chain. Processing reported data to calculate and make visible supply chain performance (provide information for decisions and actions). Ensuring the right hardware and information is provided at the right time and in the right place. Monitoring the industrial base while developing, producing, operating and retiring a system. Seeing performance deep in the supply chain that could indicate issues affecting system availability and readiness.

  2. 76 FR 67370 - Federal Property Management Regulation (FPMR); Procurement Sources and Programs

    Science.gov (United States)

    2011-11-01

    ... to agency management and personnel. List of Subjects in 41 CFR Part 101-26 Procurement sources and... MANAGEMENT REGULATIONS PART 101-26--PROCUREMENT SOURCES AND PROGRAMS 0 1. The authority for 41 CFR part 101...; Docket Number 2011-017; Sequence 1] RIN 3090-AJ19 Federal Property Management Regulation (FPMR...

  3. Development of project management data calculation models relating to dismantling of nuclear facilities. Contract research

    Energy Technology Data Exchange (ETDEWEB)

    Sukegawa, Takenori; Ohshima, Soichiro; Shiraishi, Kunio; Yanagihara, Satoshi [Department of Decommissioning and Waste Management, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai Ibaraki (Japan)

    1999-02-01

    Labor-hours necessary for dismantling activities are generally estimated based on experience, for example, as a form of unit productivity factors such as the relationship between labor-hours and weight of components dismantled which were obtained by actual dismantling activities. The project management data calculation models together with unit productivity factors for basic dismantling work activities were developed by analyzing the data obtained from the Japan Power Demonstration Reactor (JPDR) dismantling project, which will be applicable to estimation of labor-hours in various dismantling conditions. Typical work breakdown structures were also prepared by categorizing repeatable basic dismantling work activities for effective planning of dismantling activities. The labor-hours for dismantling the JPDR components and structures were calculated by using the code system for management of reactor decommissioning (COSMARD), in which the work breakdown structures and the calculation models were contained. It was confirmed that the labor-hours could be easily estimated by COSMARD through the calculations. This report describes the labor-hour calculation models and application of these models to COSMARD. (author)

  4. Pricing Policies in Managing Water Resources in Agriculture: An Application of Contract Theory to Unmetered Water

    Directory of Open Access Journals (Sweden)

    Davide Viaggi

    2013-09-01

    Full Text Available The paper explores how agricultural water pricing could contribute to lowering water demand when uses are unobserved (asymmetric information. The topic of the paper is justified by the fact that most water authorities worldwide do not control water uses at the farm scale. The study draws inspiration from the pricing policies of a Reclamation and Irrigation Board in Northern Italy. It analyses the optimal design of current tariff strategies with respect both to the actual regulator’s goals and the cost recovery objective of an ideal regulator driven by European Water Framework Directive principles and having full information. The analysis is based on the logic of a Principal-Agent model implemented as a mathematical non-linear programming model. Given the current pricing structure and assuming zero transaction costs, the results show a relevant increase in net benefits for the ideal scenario with respect to the actual one as water use costs increase. Benefits differences between the two scenarios mark a limit in value below which mechanisms able to solve the existing asymmetries between the principal and the agents are economically desirable. The study concludes by showing that the current regulator’s discriminatory strategy (pricing structure would be better justified with higher levels of cost for water use. However, the existence of non-zero transaction costs related to the control of water uses points to the need for further research in order to analyze incentive mechanisms in the absence of water metering.

  5. A stepwise approach for the management of capsular contraction syndrome in hinge-based accommodative intraocular lenses.

    Science.gov (United States)

    Page, Timothy P; Whitman, Jeffrey

    2016-01-01

    The aims of this study are to define the various stages of capsular contraction syndrome (CCS) and its effect on refractive error with hinge-based accommodating intraocular lenses (IOLs) and to describe a systematic approach for the management of the different stages of CCS. Hinge-based accommodative IOLs function via flexible hinges that vault the optic forward during accommodation. However, it is the flexibility of the IOL that makes it prone to deformation in the event of CCS. The signs of CCS are identified and described as posterior capsular striae, fibrotic bands across the anterior or posterior capsule, and capsule opacification. Various degrees of CCS may affect hinge-based accommodating IOLs in a spectrum from subtle changes in IOL appearance to significant increases in refractive error and loss of uncorrected visual acuity. The signs of CCS and its effect on IOL position and the resulting changes in refractive error are matched to appropriate treatment plans. A surgeon can avoid CCS and manage the condition if familiar with the early signs of CCS. If CCS is identified, yttrium-aluminum-garnet laser capsulotomy should be considered. If moderate CCS occurs, it may be effectively treated with insertion of a capsular tension ring. If CCS is allowed to progress to advanced stages, an IOL exchange may be necessary. Surgeons should be familiar with the stages of CCS and subsequent interventions. The steps outlined in this article help to guide surgeons in the prevention and management of CCS with hinge-based accommodative IOLs in order to provide improved refractive outcomes for patients.

  6. A stepwise approach for the management of capsular contraction syndrome in hinge-based accommodative intraocular lenses

    Directory of Open Access Journals (Sweden)

    Page TP

    2016-06-01

    Full Text Available Timothy P Page,1 Jeffrey Whitman2 1Department of Ophthalmology, Oakland University William Beaumont School of Medicine, Royal Oak, MI, 2Key-Whitman Eye Center, Dallas, TX, USA Purpose: The aims of this study are to define the various stages of capsular contraction syndrome (CCS and its effect on refractive error with hinge-based accommodating intraocular lenses (IOLs and to describe a systematic approach for the management of the different stages of CCS. Methods: Hinge-based accommodative IOLs function via flexible hinges that vault the optic forward during accommodation. However, it is the flexibility of the IOL that makes it prone to deformation in the event of CCS. The signs of CCS are identified and described as posterior capsular striae, fibrotic bands across the anterior or posterior capsule, and capsule opacification. Various degrees of CCS may affect hinge-based accommodating IOLs in a spectrum from subtle changes in IOL appearance to significant increases in refractive error and loss of uncorrected visual acuity. The signs of CCS and its effect on IOL position and the resulting changes in refractive error are matched to appropriate treatment plans. Results: A surgeon can avoid CCS and manage the condition if familiar with the early signs of CCS. If CCS is identified, yttrium–aluminum–garnet laser capsulotomy should be considered. If moderate CCS occurs, it may be effectively treated with insertion of a capsular tension ring. If CCS is allowed to progress to advanced stages, an IOL exchange may be necessary. Conclusion: Surgeons should be familiar with the stages of CCS and subsequent interventions. The steps outlined in this article help to guide surgeons in the prevention and management of CCS with hinge-based accommodative IOLs in order to provide improved refractive outcomes for patients. Keywords: z-syndrome, pseudophakic tilt, IOL subluxation, CTR, capsular tension ring, capsular fibrosis

  7. Decree 182/013 It would regulate the management of industrial solid waste and similar expenses

    International Nuclear Information System (INIS)

    2013-01-01

    It regulate of industrial solid waste management and similar expenses activities covered, exclusions, categorization, requirements, transportation, recycling and treatment, incineration, use as alternative fuel

  8. Optimal Coordinated Management of a Plug-In Electric Vehicle Charging Station under a Flexible Penalty Contract for Voltage Security

    Directory of Open Access Journals (Sweden)

    Jip Kim

    2016-07-01

    Full Text Available The increasing penetration of plug-in electric vehicles (PEVs may cause a low-voltage problem in the distribution network. In particular, the introduction of charging stations where multiple PEVs are simultaneously charged at the same bus can aggravate the low-voltage problem. Unlike a distribution network operator (DNO who has the overall responsibility for stable and reliable network operation, a charging station operator (CSO may schedule PEV charging without consideration for the resulting severe voltage drop. Therefore, there is a need for the DNO to impose a coordination measure to induce the CSO to adjust its charging schedule to help mitigate the voltage problem. Although the current time-of-use (TOU tariff is an indirect coordination measure that can motivate the CSO to shift its charging demand to off-peak time by imposing a high rate at the peak time, it is limited by its rigidity in that the network voltage condition cannot be flexibly reflected in the tariff. Therefore, a flexible penalty contract (FPC for voltage security to be used as a direct coordination measure is proposed. In addition, the optimal coordinated management is formulated. Using the Pacific Gas and Electric Company (PG&E 69-bus test distribution network, the effectiveness of the coordination was verified by comparison with the current TOU tariff.

  9. 41 CFR 102-193.20 - What are the specific agency responsibilities for records management?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are the specific agency responsibilities for records management? 102-193.20 Section 102-193.20 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT...

  10. 41 CFR 105-74.115 - Does this part affect the Federal contracts that I receive?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Does this part affect... Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services Administration 74-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE...

  11. Managing Contract Training Programs: Progress and Proposals. Institute for Studies in Higher Education Policy Paper No. 2.

    Science.gov (United States)

    Deegan, William L.

    An overview is provided of community college involvement in providing job training for industry on a contract basis. Part 1 provides background on the changing role of community colleges and the introduction of contract training as a means of addressing the growing need of organizations to train and retrain staff. Part 2 offers a national…

  12. 75 FR 391 - Medical Device Quality System Regulation Educational Forum on Risk Management Through the Product...

    Science.gov (United States)

    2010-01-05

    ...] Medical Device Quality System Regulation Educational Forum on Risk Management Through the Product Life... on Risk Management through the Product Life Cycle.'' This public workshop is intended to provide... discussed at the workshop: (1) Standards and guidance, (2) risk management in design, (3) risk management in...

  13. Joint Convention on the safety of spent fuel management and on the safety of radioactive waste management. France's answers to questions and comments received from other Contracting Parties on its second report for the JC

    International Nuclear Information System (INIS)

    2009-01-01

    The Joint Convention on the Safety of Spent Fuel Management and the Safety of Radioactive Waste Management, referred to as the 'Joint Convention', is the result of international discussions that followed the adoption of the Convention on Nuclear Safety, in 1994. France signed the Joint Convention at the General Conference of the International Atomic Energy Agency (IAEA) held on 29 September 1997, the very first day the Joint Convention was opened for signature. She approved it on 22 February 2000 and filed the corresponding instruments with the IAEA on 27 April 2000. The Joint Convention entered into force on 18 June 2001. For many years, France has been taking an active part in the pursuit of international actions to reinforce nuclear safety and considers the Joint Convention to be a key step in that direction. The fields covered by the Joint Convention have long been part of the French approach to nuclear safety. For his second report, France presented a document reflecting the viewpoints of the various stakeholders (regulatory authorities and operators). Thus, for each of the chapters in which the regulatory authority is not the only party to express its point of view, a three-stage structure was adopted: first of all a description by the regulatory authority of the regulations, followed by a presentation by the operators of the steps taken to meet the regulations and finally, an analysis by the regulatory authority of the steps taken by the operators. France received questions and comments from the other contracting parties of the joint convention and answered them in the present document

  14. Drilling contracts and incentives

    International Nuclear Information System (INIS)

    Osmundsen, Petter; Sorenes, Terje; Toft, Anders

    2008-01-01

    Shortages of rigs and personnel have encouraged discussion of designing incentive contracts in the drilling sector. However, for the drilling contracts, there are not a large variety of contract types in use. This article describes and analyses incentives for drilling contractors. These are directly represented by the compensation formats utilised in the present and in the consecutive drilling contracts. Indirectly, incentives are also provided by the evaluation criteria that oil companies use for awarding drilling assignments. Changes in contract format pose a number of relevant questions relating to resource management, and the article takes an in-depth look at some of these. Do evaluation criteria for awarding drilling assignments encourage the development of new technology and solutions? How will a stronger focus on drilling efficiency influence reservoir utilisation?

  15. 48 CFR 1816.202 - Firm-fixed-price contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Firm-fixed-price contracts. 1816.202 Section 1816.202 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 1816.202 Firm...

  16. 48 CFR 32.005 - Consideration for contract financing.

    Science.gov (United States)

    2010-10-01

    ... financing. 32.005 Section 32.005 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING 32.005 Consideration for contract financing. (a) Requirement. When a contract financing clause is included at the inception of a contract, there shall be no...

  17. 48 CFR 1316.405 - Cost-reimbursement incentive contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Cost-reimbursement incentive contracts. 1316.405 Section 1316.405 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 1316.405 Cost-reimbursement...

  18. 48 CFR 916.405 - Cost-reimbursement incentive contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Cost-reimbursement incentive contracts. 916.405 Section 916.405 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 916.405 Cost-reimbursement...

  19. 48 CFR 916.504 - Indefinite-quantity contracts.

    Science.gov (United States)

    2010-10-01

    ... indefinite-quantity, multiple award contracts to ensure that adequate consideration exists to contractually... contracts. 916.504 Section 916.504 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Indefinite-Delivery Contracts 916.504 Indefinite-quantity...

  20. 48 CFR 232.501-3 - Contract price.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract price. 232.501-3... 232.501-3 Contract price. (b) The contracting officer may approve progress payments when the contract price exceeds the funds obligated under the contract, provided the contract limits the Government's...

  1. 29 CFR 4.145 - Extended term contracts.

    Science.gov (United States)

    2010-07-01

    ...'Hara Service Contract Act Changes in Contract Coverage § 4.145 Extended term contracts. (a) Sometimes... purposes of this Act, a contract shall be deemed entered into upon the contract anniversary date which... period is a wholly new contract with respect to application of the Act's provisions and the regulations...

  2. 48 CFR 32.114 - Unusual contract financing.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Unusual contract financing... CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 32.114 Unusual contract financing. Any contract financing arrangement that deviates from this part is unusual contract financing...

  3. 48 CFR 904.7201 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 904.7201... MATTERS Public Affairs 904.7201 Contract clause. The contracting officer shall insert the clause at 952.204-75, Public Affairs, in solicitations and contracts that require the contractor to release...

  4. 48 CFR 803.7001 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 803.7001... Practices 803.7001 Contract clause. The contracting officer shall insert the clause at 852.203-71, Display of Department of Veterans Affairs Hotline poster, in solicitations and contracts expected to equal or...

  5. 48 CFR 819.7009 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 819.7009... Acquisition Program 819.7009 Contract clauses. The contracting officer shall insert VAAR clause 852.219-10... Veteran-Owned Small Business Set-Aside in solicitations and contracts for acquisitions under this subpart. ...

  6. 48 CFR 903.971 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 903.971... Contract clause. The contracting officer shall insert the clause at 952.203-70, Whistleblower Protection for Contractor Employees, in contracts that involve work to be done on behalf of DOE directly related...

  7. 48 CFR 871.212 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 871.212... Rehabilitation and Employment Service 871.212 Contract clauses. Contracting officers must use the following clauses, as appropriate, in solicitations and contracts for vocational rehabilitation and employment...

  8. 48 CFR 53.111 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contract clause. 53.111... AND FORMS FORMS General 53.111 Contract clause. Contracting officers shall insert the clause at 52.253-1, Computer Generated Forms, in solicitations and contracts that require the contractor to submit...

  9. 48 CFR 811.404 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 811.404... ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Delivery or Performance Schedules 811.404 Contract clause. When delivery is required by or on a particular date for f.o.b. destination contracts, the contracting officer...

  10. 48 CFR 925.7004 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 925.7004... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7004 Contract clause. The contracting... solicitations and contracts involving nuclear hot cell services. This clause does not flow down to second-tier...

  11. 48 CFR 22.610 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Walsh-Healey Public Contracts Act 22.610... Contracts Act, in solicitations and contracts covered by the Act (see 22.603, 22.604, and 22.605). [61 FR... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract clause. 22.610...

  12. Polymorphic Contracts

    Science.gov (United States)

    Belo, João Filipe; Greenberg, Michael; Igarashi, Atsushi; Pierce, Benjamin C.

    Manifest contracts track precise properties by refining types with predicates - e.g., {x : Int |x > 0 } denotes the positive integers. Contracts and polymorphism make a natural combination: programmers can give strong contracts to abstract types, precisely stating pre- and post-conditions while hiding implementation details - for example, an abstract type of stacks might specify that the pop operation has input type {x :α Stack |not ( empty x )} . We formalize this combination by defining FH, a polymorphic calculus with manifest contracts, and establishing fundamental properties including type soundness and relational parametricity. Our development relies on a significant technical improvement over earlier presentations of contracts: instead of introducing a denotational model to break a problematic circularity between typing, subtyping, and evaluation, we develop the metatheory of contracts in a completely syntactic fashion, omitting subtyping from the core system and recovering it post facto as a derived property.

  13. How Do Motivational Regulation Strategies Affect Achievement: Mediated by Effort Management and Moderated by Intelligence

    Science.gov (United States)

    Schwinger, Malte; Steinmayr, Ricarda; Spinath, Birgit

    2009-01-01

    It was assumed that the effect of motivational regulation strategies on achievement is mediated by effort management and moderated by intelligence. A sample of 231 11th and 12th grade German high-school students provided self-reports on their use of motivational regulation strategies and effort management and completed an intelligence test.…

  14. 48 CFR 232.704-70 - Incrementally funded fixed-price contracts.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING...'s decision and terminate for the convenience of the Government. (c) The contracting officer shall...

  15. Administrative contracts

    OpenAIRE

    Vukićević-Petković Milica

    2015-01-01

    Administrative contracts are a special type of contract where usually one of the contracting parties is a public law body and which is concluded for the performance of public service and the realization of a public interest. They go a long way since its inception to its eventual final acceptance of all the legal systems. One of the enduring characteristics of this type of contract is their disquised or unnoticed existence. This is why only monitoring their development may lead to a complete u...

  16. Statutes and contracts

    DEFF Research Database (Denmark)

    Trosborg, Anna

    1995-01-01

    and commissive acts. The findings show that the language of the law characteristically selects patterns of regulative distinct from, for example, the patterns typically selected in everyday conversational English. The characteristics of the language of the law can be interpreted within the adherence to legal......This paper is concerned with the language used in legal speech acts in legislative texts and contracts in the field of English Contract Law. The central objects of study are regulative functions with a particular view to establishing realization patterns of the rhetorical functions of directive...

  17. Contracting as a Science

    Science.gov (United States)

    2012-04-30

    disconfirmation of expectations theory to examine customer satisfaction in the procuring contracting officer (PCO)–program manager (PM) relationship in...marketing terms, finding that disconfirmed expectations lead to consumer satisfaction or dissatisfaction. The former approach presents the idea that if an...individual exerts effort, the expectation is that successful performance will occur leading to a desired result. In contracting, the theory might be

  18. 48 CFR 242.302 - Contract administration functions.

    Science.gov (United States)

    2010-10-01

    ...) Contractor estimating systems (see FAR 15.407-5); and (B) Contractor material management and accounting... report identifying significant accounting system or related internal control deficiencies. (9) For... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Contract...

  19. Maximizing Operational Efficiencies in Waste Management on the Hanford Plateau Remediation Contract in a Down-turned Market - 13484

    Energy Technology Data Exchange (ETDEWEB)

    Simiele, Connie J.; Blackford, L. Ty [CH2M HILL Plateau Remediation Contract - CHPRC (United States); West, Lori D. [East Tennessee Materials and Energy Corporation - M and EC (United States)

    2013-07-01

    Recent changes in DOE priorities and funding have pressed DOE and its contractors to look for innovative methods to sustain critical operations at sites across the Complex. At the Hanford Site, DOE Richland Operations and its prime contractor, CH2M Hill Plateau Remediation Company (CHPRC), have completed in-depth assessments of the Plateau Remediation Contract (PRC) operations that compared available funding to mission and operational objectives in an effort to maintain requisite safety and compliance margins while realizing cost savings that meet funding profiles. These assessments included confirmation of current baseline activities, identification of potential efficiencies, barriers to implementation, and potential increased risks associated with implementation. Six operating PRC waste management facilities were evaluated against three possible end-states: complete facility closure, maintaining base operations, and performing minimum safe surveillance and maintenance activities. The costs to completely close evaluated facilities were determined to be prohibitively high and this end-state was quickly dropped from consideration. A summary of the analysis of remaining options by facility, efficiencies identified, impact to risk profiles, and expected cost savings is provided in Table I. The expected cost savings are a result of: - right-sizing and cross-training work crews to address maintenance activities across facilities; - combining and sequencing 'like-moded' operational processes; - cross-cutting emergency planning and preparedness staffing; - resource redistribution and optimization; - reducing areas requiring routine surveillance and inspection. For the efficiencies identified, there are corresponding increases in risk, including a loss of breadth and depth of available resources; lengthened response time to emergent issues; inability to invest in opportunities for improvement (OFIs); potential single-point failures or non-compliancies due to

  20. Maximizing Operational Efficiencies in Waste Management on the Hanford Plateau Remediation Contract in a Down-turned Market - 13484

    International Nuclear Information System (INIS)

    Simiele, Connie J.; Blackford, L. Ty; West, Lori D.

    2013-01-01

    Recent changes in DOE priorities and funding have pressed DOE and its contractors to look for innovative methods to sustain critical operations at sites across the Complex. At the Hanford Site, DOE Richland Operations and its prime contractor, CH2M Hill Plateau Remediation Company (CHPRC), have completed in-depth assessments of the Plateau Remediation Contract (PRC) operations that compared available funding to mission and operational objectives in an effort to maintain requisite safety and compliance margins while realizing cost savings that meet funding profiles. These assessments included confirmation of current baseline activities, identification of potential efficiencies, barriers to implementation, and potential increased risks associated with implementation. Six operating PRC waste management facilities were evaluated against three possible end-states: complete facility closure, maintaining base operations, and performing minimum safe surveillance and maintenance activities. The costs to completely close evaluated facilities were determined to be prohibitively high and this end-state was quickly dropped from consideration. A summary of the analysis of remaining options by facility, efficiencies identified, impact to risk profiles, and expected cost savings is provided in Table I. The expected cost savings are a result of: - right-sizing and cross-training work crews to address maintenance activities across facilities; - combining and sequencing 'like-moded' operational processes; - cross-cutting emergency planning and preparedness staffing; - resource redistribution and optimization; - reducing areas requiring routine surveillance and inspection. For the efficiencies identified, there are corresponding increases in risk, including a loss of breadth and depth of available resources; lengthened response time to emergent issues; inability to invest in opportunities for improvement (OFIs); potential single-point failures or non-compliancies due to resource

  1. 48 CFR 619.808 - Contract negotiation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contract negotiation. 619.808 Section 619.808 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration (The 8(a) Program) 619.808 Contract negotiation...

  2. 48 CFR 4.101 - Contracting officer's signature.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contracting officer's signature. 4.101 Section 4.101 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL ADMINISTRATIVE MATTERS Contract Execution 4.101 Contracting officer's signature. Only contracting officers shall...

  3. 41 CFR 301-73.201 - What method of payment may be used for contract passenger transportation service?

    Science.gov (United States)

    2010-07-01

    ... Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 73-TRAVEL PROGRAMS Contract Passenger Transportation Services § 301-73.201 What... contractor-issued travel charge card(s), or your agency centrally billed or other established account, or a...

  4. Contingency Contracting within the Department of Defense: A Comparative Analysis

    National Research Council Canada - National Science Library

    McMillion, Chester

    2000-01-01

    .... The thesis compares and contrasts the regulations governing the contingency contracting operations, the organization structure, contingency contracting support plans, and the training requirements...

  5. Army Contract Writing System (ACWS)

    Science.gov (United States)

    2016-03-01

    2016 Major Automated Information System Annual Report Army Contract Writing System (ACWS) Defense Acquisition Management Information Retrieval...Information 4 Responsible Office 4 References 4 Program Description 5 Business Case 5 Program Status 6 Schedule 7 Performance...Program Information Program Name Army Contract Writing System (ACWS) DoD Component Army Responsible Office Program Manager References MAIS

  6. Application of machine learning methods in big data analytics at management of contracts in the construction industry

    Directory of Open Access Journals (Sweden)

    Valpeters Marina

    2018-01-01

    Full Text Available The number of experts who realize the importance of big data continues to increase in various fields of the economy. Experts begin to use big data more frequently for the solution of their specific objectives. One of the probable big data tasks in the construction industry is the determination of the probability of contract execution at a stage of its establishment. The contract holder cannot guarantee execution of the contract. Therefore it leads to a lot of risks for the customer. This article is devoted to the applicability of machine learning methods to the task of determination of the probability of a successful contract execution. Authors try to reveal the factors influencing the possibility of contract default and then try to define the following corrective actions for a customer. In the problem analysis, authors used the linear and non-linear algorithms, feature extraction, feature transformation and feature selection. The results of investigation include the prognostic models with a predictive force based on the machine learning algorithms such as logistic regression, decision tree, randomize forest. Authors have validated models on available historical data. The developed models have the potential for practical use in the construction organizations while making new contracts.

  7. Dynamic Management of Mutual Fund Advisory Contracts = Yatırım Fonu Anlaşmalarının Dinamik Yönetimi

    Directory of Open Access Journals (Sweden)

    Yaman Ö. ERZURUMLU

    2006-06-01

    Full Text Available The price of professional portfolio management provided by the mutual fund adviser depends not only on the fund characteristics but also on the fund objective, the adviser's portfolio related and management based decisions, and the portfolio performance. I analyze the advisory fee, using a survivorship bias free data set of 176 equity funds managed by 125 different advisers. Advisers benchmark the objective average but this benefit the shareholders only when the objective trend is descending. Advisers tend to reduce the cost of their marginal product through the use of derivatives or manipulate by engaging in soft dollar agreements. I find that the advisers actively manage the advisory fee contracts responding to the outcome of their management decisions. The advisory fee increases after voluntary fee reimbursement or if the adviser is not fully reimbursed for the compensation of independent directors and officers.

  8. 24 CFR 242.52 - Construction contracts.

    Science.gov (United States)

    2010-04-01

    ...; a construction management contract with a guaranteed maximum price, the final costs of which are... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Construction contracts. 242.52... MORTGAGE INSURANCE FOR HOSPITALS Construction § 242.52 Construction contracts. (a) Awarding of contract. A...

  9. Self- and Social-Regulation in Type 1 Diabetes Management During Late Adolescence and Emerging Adulthood.

    Science.gov (United States)

    Wiebe, Deborah J; Berg, Cynthia A; Mello, Daniel; Kelly, Caitlin S

    2018-03-21

    This paper aims to examine how self-regulation (i.e., cognition, emotion) and social-regulation (i.e., parents, friends, romantic partners) are interrelated risk and protective factors for type 1 diabetes management during late adolescence and emerging adulthood. Problems in cognitive (e.g., executive function) and emotional (e.g., depressive symptoms) self-regulation are associated with poorer management, both at the between- and within-person levels. Better management occurs when parents are supportive and when individuals actively regulate the involvement of others (e.g., seek help, minimize interference). Friends both help and hinder self-regulation, while research on romantic partners is limited. Facets of self- and social-regulation are important risk and protective factors for diabetes management during emerging adulthood. At this time when relationships are changing, the social context of diabetes may need to be regulated to support diabetes management. Interventions targeting those with self-regulation problems and facilitating self- and social-regulation in daily life may be useful.

  10. 41 CFR 102-74.10 - What is the basic facility management policy?

    Science.gov (United States)

    2010-07-01

    ... facility management policy? 102-74.10 Section 102-74.10 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT General Provisions § 102-74.10 What is the basic facility management policy? Executive agencies...

  11. A Classification and Analysis of National Contract Management Journal Articles from 1990 to 1999 and Journal of Supply Chain Management Articles from 1987 to 2000

    National Research Council Canada - National Science Library

    Browne, Forrest

    2001-01-01

    .... A secondary objective of this thesis was to assess the differences in subject matter between the two journals and by extension, the differences between Government contracting literature and commercial purchasing literature. The final objective of this thesis was to compile an annotated bibliography of articles primed in the contracting journal that have not been previously annotated.

  12. An Analysis of Contract Management Processes at the Space and Missile Systems Center and the Air Force Life Cycle Management Center (Wright-Patterson) Using the Contract Management Maturity Model

    Science.gov (United States)

    2012-11-28

    graduation, Capt Chang’s next assignment is at Los Angeles Air Force Base in the Space and Missile Systems Center (SMC). Capt Chang is unmarried with... married to the former Ms. Laura Hazzard, and they have three children, Madden, and twins Aubrey and Tyler. Captain Keith V. Philaphandeth is an Air...2012 SPONSORED RESEARCH TOPICS Acquisition Management  Acquiring Combat Capability via Public-Private Partnerships (PPPs)  BCA: Contractor vs

  13. Making sense of the disclosure of latent defects in financial statements and company acquisition contracts

    Directory of Open Access Journals (Sweden)

    Cornelius Killian

    2011-05-01

    Full Text Available This paper analyses the statement made by the South African Appeal Court Judge Holmes in the Phame v Paizes (1973 case and, using economic and unique South African legal principles, it examines the true legal nature of a contract to regulate company acquisitions.1 Two solutions are offered for financial managers in South Africa: (1 the contract to regulate company acquisitions is a forward contract and (2 the difficulty in identifying latent defects should not be grounds for reducing the price paid for a company or enterprise in the South African legal system.

  14. Flood Risk Management In Europe: European flood regulation

    NARCIS (Netherlands)

    Hegger, D.L.T.; Bakker, M.H.; Green, C.; Driessen, Peter; Delvaux, B.; Rijswick, H.F.M.W. van; Suykens, C.; Beyers, J-C.; Deketelaere, K.; Doorn-Hoekveld, W. van; Dieperink, C.

    2013-01-01

    In Europe, water management is moving from flood defense to a risk management approach, which takes both the probability and the potential consequences of flooding into account. In this report, we will look at Directives and (non-)EU- initiatives in place to deal with flood risk in Europe indirectly

  15. The science of laboratory and project management in regulated bioanalysis.

    Science.gov (United States)

    Unger, Steve; Lloyd, Thomas; Tan, Melvin; Hou, Jingguo; Wells, Edward

    2014-05-01

    Pharmaceutical drug development is a complex and lengthy process, requiring excellent project and laboratory management skills. Bioanalysis anchors drug safety and efficacy with systemic and site of action exposures. Development of scientific talent and a willingness to innovate or adopt new technology is essential. Taking unnecessary risks, however, should be avoided. Scientists must strategically assess all risks and find means to minimize or negate them. Laboratory Managers must keep abreast of ever-changing technology. Investments in instrumentation and laboratory design are critical catalysts to efficiency and safety. Matrix management requires regular communication between Project Managers and Laboratory Managers. When properly executed, it aligns the best resources at the right times for a successful outcome. Attention to detail is a critical aspect that separates excellent laboratories. Each assay is unique and requires attention in its development, validation and execution. Methods, training and facilities are the foundation of a bioanalytical laboratory.

  16. Service quality in contracted facilities.

    Science.gov (United States)

    Rabbani, Fauziah; Pradhan, Nousheen Akber; Zaidi, Shehla; Azam, Syed Iqbal; Yousuf, Farheen

    2015-01-01

    The purpose of this paper is to explore the readiness of contracted and non-contracted first-level healthcare facilities in Pakistan to deliver quality maternal and neonatal health (MNH) care. A balanced scorecard (BSC) was used as the assessment framework. Using a cross-sectional study design, two rural health centers (RHCs) contracted out to Aga Khan Health Service, Pakistan were compared with four government managed RHCs. A BSC was designed to assess RHC readiness to deliver good quality MNH care. In total 20 indicators were developed, representing five BSC domains: health facility functionality, service provision, staff capacity, staff and patient satisfaction. Validated data collection tools were used to collect information. Pearson χ2, Fisher's Exact and the Mann-Whitney tests were applied as appropriate to detect significant service quality differences among the two facilities. Contracted facilities were generally found to be better than non-contracted facilities in all five BSC domains. Patients' inclination for facility-based delivery at contracted facilities was, however, significantly higher than non-contracted facilities (80 percent contracted vs 43 percent non-contracted, p=0.006). The study shows that contracting out initiatives have the potential to improve MNH care. This is the first study to compare MNH service delivery quality across contracted and non-contracted facilities using BSC as the assessment framework.

  17. Skeletal muscle cell contraction reduces a novel myokine, chemokine (C-X-C motif) ligand 10 (CXCL10): potential roles in exercise-regulated angiogenesis.

    Science.gov (United States)

    Ishiuchi, Yuri; Sato, Hitoshi; Tsujimura, Kazuki; Kawaguchi, Hideo; Matsuwaki, Takashi; Yamanouchi, Keitaro; Nishihara, Masugi; Nedachi, Taku

    2018-01-01

    Accumulating evidence indicates that skeletal muscle secrets proteins referred to as myokines and that exercise contributes to their regulation. In this study, we propose that chemokine (C-X-C motif) ligand 10 (CXCL10) functions as a novel myokine. Initially, we stimulated differentiated C2C12 myotubes with or without electrical pulse stimulation (EPS) to identify novel myokines. Cytokine array analysis revealed that CXCL10 secretion was significantly reduced by EPS, which was further confirmed by enzyme-linked immunosorbent assay and quantitative polymerase chain reaction analysis. Treadmill experiments in mice identified significant reduction of Cxcl10 gene expression in the soleus muscle. Additionally, contraction-dependent p38 MAPK activation appeared to be involved in this reduction. Furthermore, C2C12 conditioned medium obtained after applying EPS could induce survival of MSS31, a vascular endothelial cell model, which was partially attenuated by the addition of recombinant CXCL10. Overall, our findings suggest CXCL10 as a novel exercise-reducible myokine, to control endothelial cell viability.

  18. 48 CFR 227.7009-3 - Additional clauses-contracts except running royalty contracts.

    Science.gov (United States)

    2010-10-01

    ...-contracts except running royalty contracts. 227.7009-3 Section 227.7009-3 Federal Acquisition Regulations...—contracts except running royalty contracts. The following clauses are examples for use in patent release and settlement agreements, and license agreements not providing for payment by the Government of a running...

  19. INDEFINITE CONTRACT REVIEW 2000

    CERN Multimedia

    Division des ressources humaines

    2000-01-01

    The Director-General has decided to review staff members in professional categories 2 to 5 satisfying the criteria for consideration for the award of an indefinite contract, in accordance with Article R II 1.20 of the Staff Regulations. Staff members holding a fixed-term contract which it has been decided not to renew will not be considered. The following stages are foreseen:1.\tCandidates qualifying for review in accordance with Article R II 1.20 of the Staff Regulations and the Administrative Circular N° 9 will be contacted by Human Resources Division. 2.\tThe criteria as to when staff members qualify for review are described in Administrative Circular N° 9. These include the following:staff members who are in their fourth year of service on a fixed-term contract;in addition, for staff members having three years or more of previous relevant service in the Organization on a contract of limited duration (or term-contract) and upon proposal by the division leader concerned, consid...

  20. INDEFINITE CONTRACT REVIEW 2001

    CERN Multimedia

    Human Resources Division

    2001-01-01

    The Director-General has decided to review staff members in professional categories 2 to 5 satisfying the criteria for consideration for the award of an indefinite contract, in accordance with Article R II 1.20 of the Staff Regulations. Staff members holding a fixed-term contract which it has been decided not to renew will not be considered. The following stages are foreseen: 1. Candidates qualifying for review in accordance with Article R II 1.20 of the Staff Regulations and the Administrative Circular N° 9 will be contacted by Human Resources Division. 2. The criteria as to when staff members qualify for review are described in Administrative Circular N° 9. These include the following: staff members who are in their fourth year of service on a fixed-term contract; in addition, for staff members having three years or more of previous relevant service in the Organization on a contract of limited duration (or term-contract) and upon proposal by the division leader concerned, consideration fo...